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Sample records for claude amra norbert

  1. Claude Ruggieri

    NASA Technical Reports Server (NTRS)

    2004-01-01

    During the 19th century, rocket enthusiasts and inventors began to appear in almost every country. Some people thought these early rocket pioneers were geniuses, and others thought they were crazy. Claude Ruggieri, an Italian living in Paris, apparently rocketed small animals into space as early as 1806. The payloads were recovered by parachute. As depicted here by artist Larry Toschik, French authorities were not always impressed with rocket research. They halted Ruggieri's plans to launch a small boy using a rocket cluster. (Reproduced from a drawing by Larry Toschik and presented here courtesy of the artist and Motorola Inc.)

  2. On Norbert Wiener on language

    NASA Astrophysics Data System (ADS)

    Julià, Pere

    2001-06-01

    Norbert Wiener (1948, 1950) subscribed to the traditional outlook on language as a formal object (L)—a system of forms and rules that can presumably be described in abstraction from speakers, listeners, and their interaction with the world and with themselves. Information and communication theories, which Wiener also pioneered, similarly reify the object of study in lieu of treating it as the natural phenomenon it obviously is. Terms like `input,' `output,' `message,' `transmission,' `processing,' etc. implicitly legitimize older views as to the use of language as a "tool" or "instrument" for expressing feelings, thoughts, ideas, etc.; more important yet, they stand in the way of a satisfactory account of self-referentiality, which finds its natural place within the broader context of self-regulation. Cybernetics may be said to have lost sight of the "kybernetes," which gave it its name. The ways in which language participates in—or even helps to integrate—the behavior of the total human individual in his/her adaptation to their milieu casts a new light on questions about self-organization, meaning, experience, and creativity.

  3. Pupil-sparing third nerve palsies and hemiataxia: Claude's and reverse Claude's syndrome.

    PubMed

    Bateman, James R; Murty, Pavan; Forbes, Michael; Collier, Kisha Young; Tememe, Danoushka; Marchena, Octavio de; Powers, William J

    2016-06-01

    We report two patients with midbrain infarction with pupil-sparing third nerve palsies and hemiataxia: one with contralateral ataxia (Claude's syndrome) and one with ipsilateral ataxia (which we refer to as reverse Claude's syndrome). We highlight the importance of a thorough neurologic evaluation with partial oculomotor palsies and describe, to our knowledge, the fourth account in the literature of a pupil-sparing third nerve palsy with ipsilateral cerebellar ataxia. PMID:26883351

  4. Rocks at Belle-Isle, Port-Domois, Claude Monet

    ERIC Educational Resources Information Center

    Rauch, Marion Cosgrove

    2004-01-01

    This article is a description of the artist Claude Monet. The article describes the life and art of Claude Monet, focusing in on his work, Rocks at Bell-Isle, Port-Domois. A brief discussion of the significant elements of the painting is provided. The article also includes a list of discussion questions and suggested classroom activities.

  5. Compact Claude cycle refrigerator for laboratory use

    NASA Technical Reports Server (NTRS)

    Hiersaki, Y.; Kaneko, M.; Munekata, T.; Baba, Y.; Matsubara, Y.; Yasukochi, K.

    1983-01-01

    A Claude cycle refrigerator with a three stage reciprocating expansion engine is described. Instead of a cam mechanism, valves are driven directly by magnetic solenoids operated by means of a micro processor control system. A swash plate mechanism is used to convert reciprocating motion of the expander pistons to rotary motion. A refrigeration capacity of 8 watts was achieved at 4.5 K with the operating pressure of 1.1 MPa and flow rate of 2.4 g/sec.. An effect of overintake operation was studied. Experimental results show that the efficiency of the expander has a peak point in the region of overintake operation with constant cycle speed, which agrees with theoretical results. The electrically controlled valve system is useful to vary the valve timing to achieve an optimum condition of operation.

  6. A note about Norbert Wiener and his contribution to Harmonic Analysis and Tauberian Theorems

    NASA Astrophysics Data System (ADS)

    Almira, J. M.; Romero, A. E.

    2009-05-01

    In this note we explain the main motivations Norbert Wiener had for the creation of his Generalized Harmonic Analysis [13] and his Tauberian Theorems [14]. Although these papers belong to the most pure mathematical tradition, they were deeply based on some Engineering and Physics Problems and Wiener was able to use them for such diverse areas as Optics, Brownian motion, Filter Theory, Prediction Theory and Cybernetics.

  7. Variability, Constraints, and Creativity: Shedding Light on Claude Monet.

    ERIC Educational Resources Information Center

    Stokes, Patricia D.

    2001-01-01

    Discusses how creative individuals maintain high levels of variability, examining how Claude Monet's habitually high level of variability in painting was acquired during his childhood and early apprenticeship and maintained throughout his adult career by a continuous series of task constraints imposed by the artist on his own work. For Monet,…

  8. Claude Claremont's Contribution to the History of Science and Engineering.

    ERIC Educational Resources Information Center

    Hallenberg, Harvey R.

    1995-01-01

    Discusses the contributions of Claude Claremont to science education for children and his 1937 book, "Spanning Space," which outlines the building of models of bridges and other structures out of paper. Also describes how children and their teachers can build a model strut tower and a steam engine. (MDM)

  9. Reconsidering Feminisms and the Work of Norbert Elias for Understanding Gender, Sport and Sport-Related Activities

    ERIC Educational Resources Information Center

    Mansfield, Louise

    2008-01-01

    This paper reconsiders the relationships between feminist perspectives and the figurational/process-sociological perspective of Norbert Elias for understanding gender, sport and sport-related activities. The main aim of the article is to respond to Colwell's claim that there are differences between feminist and figurational approaches to…

  10. Variability, constraints, and creativity. Shedding light on Claude Monet.

    PubMed

    Stokes, P D

    2001-04-01

    Recent experimental research suggests 2 things. The first is that along with learning how to do something, people also learn how variably or differently to continue doing it. The second is that high variability is maintained by constraining, precluding a currently successful, often repetitive solution to a problem. In this view, Claude Monet's habitually high level of variability in painting was acquired during his childhood and early apprenticeship and was maintained throughout his adult career by a continuous series of task constraints imposed by the artist on his own work. For Monet, variability was rewarded and rewarding. PMID:11330236

  11. The aesthetics of laboratory inscription: Claude Bernard's Cahier Rouge.

    PubMed

    Sattar, Atia

    2013-03-01

    This essay explores the aesthetic sensibilities of the French physiologist Claude Bernard (1813-1878). In particular, it analyzes the Cahier Rouge (1850-1860), Bernard's acclaimed laboratory notebook. In this notebook, Bernard articulates the range of his experience as an experimental physiologist, juxtaposing without differentiation details of laboratory procedure and more personal queries, doubts, and reflections on experimentation, life, and art. Bernard's insights, it is argued, offer an aesthetic and phenomenological template for considering experimentation. His physiological point of view ranges from his own bodily aesthesis or sensory perception, through personal reflections on scientific discovery as an artistic process, to a broader metaphysical conception of life as an artistic creation. Such an aesthetic approach to physiology enables Bernard to reconcile his empirical methodology and his romantic idealism; it offers the history of laboratory science a framework for considering the individual, bodily, and emotional labor inherent in physiological experimentation. PMID:23789508

  12. Norbert Elias's motion pictures: history, cinema and gestures in the process of civilization.

    PubMed

    Algazi, Gadi

    2008-09-01

    Norbert Elias's project in The process of civilization (1939) involved reconstructing invisible movement--both the slow tempoof long-term historical change and the modification of psychic structures and embodied dispositions. To do this, he resorted to uncommon devices: treating historical texts as constituting a series amenable to a rudimentary discourse analysis, he constructed an imagined 'curve of civilization' serving as an approximation of the hidden process of change. Elias's curve was not supposed to represent single past states, but movement itself, its direction and pace. This novel concept of historical representation was related to the perception of cinema as a new medium making actual movement visible. But beyond making it possible to imagine how one could telescope long-term historical process, cinema also held the promise of serving as a microscope, making the minute movements of the human body, gestures and manners available for close inspection. While anthropologists were devising ways of using the new medium to document fleeting gestures and bodily postures, it was used by popular audiences as a source for remodelling behaviour and acquiring polite manners and body techniques, as noticed by such acute observers as Marcel Mauss and Joseph Roth. Hence, popular appropriation of the cinema gave rise to a heightened awareness of the historicity of gestures and the changing modalities of their transmission. Cinema was itself part of the accelerated motion of history, of a perceived change of pace in the process of civilization, which in its turn shed light on its historical antecedents and played an essential role in rethinking the notion of civilization and culture. PMID:19227624

  13. Claude Lévi-Strauss on Race, History, and Genetics

    PubMed Central

    Müller-Wille, Staffan

    2015-01-01

    In 1952, the French anthropologist Claude Lévi-Strauss published a small booklet titled Race and History. It formed part of a series of pamphlets on the so-called “race-question” by leading anthropologists and geneticists, which UNESCO published as part of its campaign against racism. Roughly twenty years later, in 1971, UNESCO invited Lévi-Strauss to give a lecture to open the International Year of Action to Combat Racism and Racial Discrimination. This time the lecture, titled “Race and culture,” caused a scandal. In 2005, on occasion of the Organisation’s 60th anniversary, Lévi-Strauss was once again invited by UNESCO to give a lecture. It followed the same lines as his 1971 speech, but now met with acclaim. In my paper I will analyze Lévi-Strauss’ interventions with respect to their reliance on contemporary genetics. Lévi-Strauss always saw a close analogy between structuralist anthropology and genetics, and derived his anti-evolutionary stance from the combinatory logic that both disciplines endorsed. I will argue, that it was this combinatory logic which created room for historical contingency and agency in Lévi-Strauss’ understanding of the history of humankind. PMID:25685173

  14. Hyperglycaemia: imitating Claude Bernard's piqûre with drugs.

    PubMed

    Feldberg, W; Pyke, D; Stubbs, W A

    1985-11-01

    Hyperglycaemia lasting for hours, has been produced in unanesthetized cats, rabbits and rats by injection into the cerebral ventricles or the cisterna magna of a variety of drugs (morphine, etorphine, pethidine, beta-endorphin, enkephalin, bombesin, TRH, cholecystokinin, naloxone, propranolol, phentolamine, chloralose, magnesium chloride and GABA). These drugs probably act at the ventral surface of the brainstem and initiate a sympathetic discharge to the adrenals which results in a prolonged release of relatively small amounts of adrenaline. When adrenaline is released in this way hyperglycaemia may be the only effect. The mechanism of the piqûre hyperglycaemia of Claude Bernard may be the same, although Bernard assumed that it resulted from an effect on the floor of the fourth ventricle, i.e. on the dorsal surface of the brainstem. However, it is clear from his description that his trochar not only pricked the floor of the fourth ventricle but penetrated to the ventral surface of the brainstem. Release of adrenaline from the adrenals is usually regarded as a stress response, as in fight, flight, fear or rage when it is suddenly released in large amounts and produces its typical cardiovascular and ocular reactions. The results now obtained with drugs injected intraventricularly or intracisternally suggest an additional physiological role for adrenaline when it is released over prolonged periods and in relatively small amounts producing only hyperglycaemia. Such a release may play a role in the day-to-day control of blood glucose, and its disturbance might underlie non-insulin-dependent diabetes. PMID:2866209

  15. Trochlear nerve palsy associated with claude bernard-horner syndrome after brainstem stroke.

    PubMed

    Bazan, Rodrigo; Braga, Gabriel Pereira; Gomes, Daniela Laranja; Yamashita, Seizo; Betting, Luiz Eduardo; Resende, Luiz Antonio de Lima

    2011-09-01

    The association of unilateral trochlear nerve palsy with Claude Bernard-Horner syndrome represents a rare clinical condition. We present the case of a patient with this unusual presentation. The investigation performed implicated cerebrovascular disease as the underlying cause of the condition in this patient. PMID:22114581

  16. Trochlear Nerve Palsy Associated with Claude Bernard-Horner Syndrome after Brainstem Stroke

    PubMed Central

    Bazan, Rodrigo; Braga, Gabriel Pereira; Gomes, Daniela Laranja; Yamashita, Seizo; Betting, Luiz Eduardo; Resende, Luiz Antonio de Lima

    2011-01-01

    The association of unilateral trochlear nerve palsy with Claude Bernard-Horner syndrome represents a rare clinical condition. We present the case of a patient with this unusual presentation. The investigation performed implicated cerebrovascular disease as the underlying cause of the condition in this patient. PMID:22114581

  17. Children's Invented Notations and Verbal Responses to a Piano Work by Claude Debussy

    ERIC Educational Resources Information Center

    Elkoshi, Rivka

    2015-01-01

    This study considers the way children listen to classical music composed for them and the effect of age on their spontaneous invented notations and verbal responses. The musical selection is a piano piece for children by Claude Debussy:"'Jimbo's Lullaby" from "Children's Corner". Two hundred and nine children 4-9.5-years-old…

  18. Development of small size Claude cycle helium refrigerator with micro turbo-expander

    NASA Astrophysics Data System (ADS)

    Izumi, H.; Harada, S.; Matsubara, K.; Saito, S.

    The present Claude-cycle He refrigerator, developed for design performance of 5 W at 4.5 K, employs two-stage expansion microturbines, perforated plate heat exchangers, and a single-stage, screw-type compressor. Attention is given to design and test results of the major system components, with emphasis on microturbine performance. The performance data obtained lead to a 50-percent estimated efficiency at the design point for both stages of the expander.

  19. [Claude Balme, a caregiver of the Egyptian expedition of Bonaparte (1766-1850)].

    PubMed

    Ségal, Alain

    2014-01-01

    The author explains military surgeon Balme's biograpyhy, especially during Bonaparte's Egyptian campaign (1798-1801). As there is some possible confusion with another Claude Balme, some archives deserve to be closely scrutinized. Through Balme's reports the author insists on his courageous part in several scurvy or plague epidemics. He was himself marked on his face; he ended his life in Lyons as a town-councillor. PMID:25966538

  20. Plant anesthesia supports similarities between animals and plants: Claude Bernard's forgotten studies.

    PubMed

    Grémiaux, Alexandre; Yokawa, Ken; Mancuso, Stefano; Baluška, František

    2014-01-01

    The French scientist Claude Bernard (1813-1878) is famous for his discoveries in physiology and for introducing rigorous experimental methods to medicine and biology. One of his major technical innovations was the use of chemicals in order to disrupt normal physiological function to test hypotheses. But less known is his conviction that the physiological functions of all living organisms rely on the same underlying principles. He hypothesized that similarly to animals, plants are also able to sense changes in their environment. He called this ability "sensitivity." In order to test his ideas, he performed anesthesia on plants and the results of these experiments were presented in 1878 in "Leçonssur les phénomènes de la vie communs aux animaux et aux végétaux." The phenomena described by Claude Bernard more than a century ago are not fully understood yet. Here, we present a short overview of anesthetic effects in animals and we discuss how anesthesia affects plant movements, seed germination, and photosynthesis. Surprisingly, these phenomena may have ecological relevance, since stressed plants generate anesthetics such as ethylene and ether. Finally, we discuss Claude Bernard's interpretations and conclusions in the perspective of modern plant sciences. PMID:24476640

  1. Between the laboratory and the museum: Claude Bernard and the problem of time.

    PubMed

    Schmidgen, Henning

    2013-01-01

    This paper explores the relation between biological and historical time with respect to Claude Bernard's Lectures on the Phenomena of Life Common to Animals and Plants (1878). These lectures mirror Bernard's turn from the experimental physiology of animal organisms to a "general physiology" of elementary organisms, or cells, and discuss the problematic interrelation of science, life, and time. The paper argues that experimental life sciences in Bernard's sense are always also "living sciences," i.e., sciences in dynamic development. The perspectives of this conception are discussed with reference to Hans-Jörg Rheinberger's historical studies concerning the materiality and semiotics of "experimental systems." PMID:23888823

  2. Composite turbine blade design options for Claude (open) cycle OTEC power systems

    SciTech Connect

    Penney, T R

    1985-11-01

    Small-scale turbine rotors made from composites offer several technical advantages for a Claude (open) cycle ocean thermal energy conversion (OTEC) power system. Westinghouse Electric Corporation has designed a composite turbine rotor/disk using state-of-the-art analysis methods for large-scale (100-MW/sub e/) open cycle OTEC applications. Near-term demonstrations using conventional low-pressure turbine blade shapes with composite material would achieve feasibility and modern credibility of the open cycle OTEC power system. Application of composite blades for low-pressure turbo-machinery potentially improves the reliability of conventional metal blades affected by stress corrosion.

  3. From bench to bedside: Claude Bernard, Henry K. Beecher, MD, and science in anesthesia.

    PubMed

    Edwards, Matthew L

    2013-04-01

    Success with the medical management of pain grew tremendously after William Thomas Green Morton's successful demonstration of surgical anesthesia in 1846: Henry K. Beecher's clinical and experimental contributions to anesthesia during and after World War II had a profound impact on how clinicians and experimentalists study human populations in medicine. Beecher found that pain research required human subjects because pain was different for each individual. Nearly 100 years before Beecher, Claude Bernard similarly considered the complexity and uniqueness of human research subjects. Bernard and Beecher both preferred animal subjects in research when appropriate, but suggested that studies involving some mental, bodily, and cognitive processes required human subjects. Although Beecher and Bernard's lives did not overlap, these two men similarly confronted the issues of complexity in human and animal research, particularly in those phenomena involving higher cognitive functions. PMID:24205750

  4. A right to life for the unborn? The current debate on abortion in Germany and Norbert Hoerster's legal-philosophical justification for the right to life.

    PubMed

    Simon, A

    2000-04-01

    Rights to life for unborn humans and to abortion with impunity are incompatible. This observation by the German legal philosopher Norbert Hoerster contains a fundamental criticism of the state regulation on abortion in Germany. The regulation regards abortion as unlawful, but declines to prosecute if the abortion is conducted within the first three months of pregnancy and the pregnant woman received counseling at least three days prior to terminating the pregnancy. In contrast to the German legislature, Hoerster is in favor of setting the beginning of a right to life at birth. With this suggestion and the consequent demand for a general legalization of abortion, Hoerster himself has become the target of harsh criticism. The following article analyzes Hoerster's position and that of his opponents against the background of the current abortion debate in Germany. The consequences for dealing with the handicaps of Hoerster's suggested regulations will also be addressed. PMID:10833137

  5. Claude Bernard and an introduction to the study of experimental medicine: "physical vitalism," dialectic, and epistemology.

    PubMed

    Normandin, Sebastian

    2007-10-01

    This article explores the profound impact of the thought of Claude Bernard (1813-78) and his philosophy of experimentalism elaborated in his masterwork An Introduction to the Study of Experimental Medicine. I argue that Bernard's far-ranging theoretical impact on medicine and biology marks the end of conventional vitalism and the elusive notion of a "vital force" as a legitimate scientific concept. His understanding of medicine is as epistemologically significant in its time as Newton's contribution was to the physical sciences in the seventeenth century. This essay treats Bernard's philosophical ambitions seriously, exploring his important, even central, role in the mental world of nineteenth-century France. This includes his influence on Henri Bergson (1859-1941) and other late-nineteenth century thinkers. The subtext of Bernard's experimental epistemology is also contrasted with a key idealist philosopher of the period, the German Arthur Schopenhauer (1788-1860), and placed in the context of the larger European philosophical sphere. In contrast to much of mid-nineteenth-century philosophy, Bernard, in creating the framework for experimental medicine, argued for an experimental approach in which a priori assumptions were to be strictly constrained. Bernard's thoughts on the nature of experiment put an end to "systems" in medicine, ironically by replacing all previous medical philosophies with the all-embracing "system" of experiment. And yet, while "vital forces" fade after Bernard, a form of vitalism still flourishes. Even in Bernard's own work, in the struggle with concepts like determinism, complexity, and causality, there is a realization of the unique character of living function in a kind of "physical vitalism." PMID:17576723

  6. [Claude Bernard: a personal scientific fame that he probably would have not appreciated].

    PubMed

    Cugini, P

    2004-04-01

    Claude Bernard has been a great medical physiologist of the ninenteenth century, who was able to convince biologists and physicians that the "experimental method" can and must be applied to the phenomena of living matter, as it is applied in physics and chemistry. With the concept of the "universality of the experimental method", the Modern Experimental Medicine begun to exist. However, C. Bernard deserves of further honor, having identified and promulgated a law of the living matter, i.e., the law concerning the "constancy of the interior biological environment". Such a law was later consacrated in 1929 by G.W. Cannon with the term "homeostasis". The homeostatic conception of biological functions had a great epistemological impact in the history of biology and medicine. As a matter of fact, all the modern biologists and physicians are today educated at the light of the homeostatic systems. Accordingly, C. Bernard is celebrated in his fame as the tutor of scientific medicine. Reading, however, what C. Bernard has written on the personalism and the eponimy of scientific ideas, one is prone to think that he would have not appreciated the dogmatic exaltation, the cult of his ideas on the biological constancy. He was aware that "... it is a fundamental rule in science to modify and change the ideas going on". And again "... But, since these ideas are not immutable verities, one must be ready to abandon and modify them when they cease to represent the reality". And again "The systems and doctrines are personal and pretend to be immortal and to preserve their personality. The experimental method, however, is impersonal; it zeroes the individuality and sacrifices the particular ideas of the a single person in favor of a general verity, which is established by means of the experimental criterion". And again "The great persons have never been promoters of absolute ed eternal verities in experimental sciences". And again "Any person who made the science to proceed, never

  7. The Scriptural Cantatas "Esther" and "Jacob, et Rachel" of Elisabeth-Claude Jacquet de La Guerre: Historical Context and Performance Practice

    ERIC Educational Resources Information Center

    Buckley, Elizabeth M.

    2009-01-01

    This project explores two sacred cantatas of Elisabeth-Claude Jacquet de La Guerre, "Esther" and "Jacob, et Rachel". The cultural milieu in which the sacred cantatas of Jacquet de La Guerre were written and performed will be discussed, as well as possible venues for their original performances, including the Parisian salon, and the Royale maison…

  8. [The chief surgeon Claude Louis Sommé (1772-1855) French military physician, surgeon of Antwerp hospital].

    PubMed

    Tricot, Jean-pierre

    2015-01-01

    Claude Louis Sommé was born in Paris in 1772. After surgical studies between 1790 and 1792, he successfully embraced a military career in the armies of Napoleon at different fronts and in several hospitals. In 1806 he submitted his doctoral thesis at the Special Medical School of Strasburg, Dissertation upon Pain. The same year he presented his dismissal from he imperial armies and became chief-surgeon at the St Elisabeth hospital of Antwerp where he stayed on duty until his death in 1855. Sommé wrote a lot of medical books: surgical, anatomical and physiological. After the battle of Waterloo one third of the injured soldiers were transferred to Antwerp and were attended in his department. He also played an important role as a professor at the Primary Medical School of Antwerp. Sommé also created the botanical garden of Antwerp, close to the hospital. PMID:27029134

  9. From Claude Bernard to the Batcave and Beyond: Using Batman as a Hook for Physiology Education

    ERIC Educational Resources Information Center

    Zehr, E. Paul

    2011-01-01

    Communicating physiology to the general public and popularizing science can be tremendously rewarding activities. Providing relevant and compelling points of linkage, however, between the scientific experiences and the interests of the general public can be challenging. One avenue for popularizing science is to link scientific concepts to images,…

  10. Longitudinal Study Year I: Claude Watson School for the Arts, Spring Garden Campus.

    ERIC Educational Resources Information Center

    Turner, Samantha

    A research report on the attitudes of students, parents, and staff of an Ontario school for the arts (grades 4-8) is divided into five sections. The first section details the school's establishment, goals, admissions procedure, core program, faculty, and facilities. The second section describes the evaluation procedure. Areas evaluated were…

  11. The 2014 Claude Bernard Distinguished Lecture: the social contract of learning.

    PubMed

    Carroll, Robert G

    2015-03-01

    The shift to competency-based education expands the role of the teacher from that of a provider of information and into a shaper of knowledge, skills, and attitudes. These roles are facilitated by establishing a social contract between the instructor and learner, a contract that clearly defines the rights and duties of each. Adopting greater responsibility for the development of competencies in our learners allows faculty members to truly have an impact by shaping the behaviors of learners. PMID:25727463

  12. The 2014 Claude Bernard Distinguished Lecture: The Social Contract of Learning

    ERIC Educational Resources Information Center

    Carroll, Robert G.

    2015-01-01

    The shift to competency-based education expands the role of the teacher from that of a provider of information and into a shaper of knowledge, skills, and attitudes. These roles are facilitated by establishing a social contract between the instructor and learner, a contract that clearly defines the rights and duties of each. Adopting greater…

  13. On Agency and Structure: Pierre Bourdieu and Jean-Claude Passeron's Theory of Symbolic Violence.

    ERIC Educational Resources Information Center

    Lakomski, Gabriele

    1984-01-01

    The theory of symbolic violence, a structuralist theory of socialization and reproduction of social inequality, is analyzed and criticized as insinuating a radical stance while hiding its objectivist nature and defeatist assumptions. The central concepts of power, power relations, habitus, and the term "arbitrary" are discussed. (MJL)

  14. From Claude Bernard to the Batcave and beyond: using Batman as a hook for physiology education.

    PubMed

    Zehr, E Paul

    2011-03-01

    Communicating physiology to the general public and popularizing science can be tremendously rewarding activities. Providing relevant and compelling points of linkage, however, between the scientific experiences and the interests of the general public can be challenging. One avenue for popularizing science is to link scientific concepts to images, personalities, and icons in popular culture. Currently, comic book superhero movies and television shows are extremely popular, and Batman was used as the vehicle for popularizing concepts of exercise science, neuroscience, and physiology in my recent book, Becoming Batman: the Possibility of a Superhero. The objective of this book was to bring scientific understanding to the broader public by using the physical image and impression everyone has of Batman and his abilities and then connecting this to the underlying science. The objective of this article is to share some of the details of the process and the positive and negative outcomes of using such an approach with other academics who may be interested in similar activities. It is my goal that by sharing this experience I may stimulate like-minded readers to initiate their own similar projects and to also be emboldened to try and integrate popular culture touchstones in their own teaching practice. PMID:21385994

  15. The Claude Bernard Lecture, 1989 - Deterministic chaos: The science and the fiction

    NASA Astrophysics Data System (ADS)

    Ruelle, D.

    1990-02-01

    A general review of the ideas of chaos is presented. Particular attention is given to the problem of finding out whether or not various time evolutions observed in nature correspond to low-dimensional deterministic dynamics. The 'dimensions' of the order 6 that are obtained are found to be very close to the upper bound 2log(10)N permitted by the Grassberger-Procaccia algorithm (1983).

  16. Obesity and Gestational Diabetes Mellitus Pathways for Programming in Mouse, Monkey, and Man—Where Do We Go Next? The 2014 Norbert Freinkel Award Lecture.

    PubMed

    Friedman, Jacob E

    2015-08-01

    Obesity and gestational diabetes mellitus continue to increase worldwide and span the spectrum of age, race, ethnicity, and socioeconomic status. Alarmingly, 1 in 10 infants and toddlers is obese, and 1 in 5 youths is both obese and at risk for metabolic syndrome prior to puberty. The mechanisms underlying how poor maternal health imparts risk for future metabolic disease in the offspring are beginning to emerge in deeply phenotyped human and nonhuman primate models. Maternal diet and obesity impact fuels, hormones, and inflammation with powerful effects on fetal metabolic systems. These are accompanied by persistent changes in the infant microbiome and epigenome and in offspring behavior. These results suggest that gestational and lactational dietary exposures are driving health risks in the next generation. Whether maternal diet can prevent changes in the womb to alter infant life-course disease risk is still unknown. Controlled, mechanistic studies to identify interventions are sorely needed for a healthier next generation. PMID:26207051

  17. Comment on 'Compositional convection in a reactive crystalline mush and melt differentiation' by Stephen Tait and Claude Jaupart

    NASA Astrophysics Data System (ADS)

    Scoon, Roger N.

    1994-06-01

    At the end of their analysis of convection in magma chambers, Tait and Jaupart (1992) 'speculated' that the platiniferous dunitic pipes in the Bushveld Complex, South Africa, are 'fossil chimney structure', which developed by a process of 'compositional convection.' A hypothesis that accounts for all of the characteristics of the platiniferous dunitis pipes has not been establihsed, bu the evidence against Tait and Jaupart's suggestions is considerable: (1) a two-stage hypotheis should by entrained; (2) the magneusium dunites are primitive rocks that are unlikely to be related to residual liquids; (3) residual liquids evolved from the Lower Zone (LZ) - Lower Critical Zone (LCZ) would not be sufficiently differentiated to account for the iron-rich assemblages; (4) suitably iron-rich residual melts may be derived from the Upper Critical Zone (UCZ), but they would be extremely dense amd liable to drain downward; and (5) the absence of plagioclase is not compatible with 'typical' interstitial liquids.

  18. Perception of the A/H1N1 influenza pandemic and acceptance of influenza vaccination by Université Claude Bernard Lyon 1 staff: A descriptive study

    PubMed Central

    Amour, Sélilah; Djhehiche, Khaled; Zamora, Adeline; Bergeret, Alain; Vanhems, Philippe

    2015-01-01

    We assessed the perception and attitudes of university staff, including medical school and other science specialties, toward the 2009 A/H1N1 influenza pandemic and influenza vaccination program. A cross-sectional online survey was conducted among 4,529 university personnel on October 19–20, 2009. Seven hundred (15%) employees participated in the study. Only 18% were willing to be vaccinated, men more than women (29% versus 9%, P < 0.001), and professors/researchers more than administrative/technical staff (30% vs. 6%, P < 0.001). Intention to be vaccinated was insufficient. Additional efforts are needed to improve information dissemination among university staff. Medical university personnel should receive more information to increase vaccine coverage and protect them as well as patients. PMID:25715115

  19. A Space-Time Adaptive Method for Simulating Complex Cardiac Dynamics

    NASA Astrophysics Data System (ADS)

    Cherry, E. M.; Greenside, H. S.; Henriquez, C. S.

    2000-03-01

    A new space-time adaptive mesh refinement algorithm (AMRA) is presented and analyzed which, by automatically adding and deleting local patches of higher-resolution Cartesian meshes, can simulate quantitatively accurate models of cardiac electrical dynamics efficiently in large domains. We find in two space dimensions that the AMRA is able to achieve a factor of 5 speedup and a factor of 5 reduction in memory while achieving the same accuracy compared to a code based on a uniform space-time mesh at the highest resolution of the AMRA method. We summarize applications of the code to the Luo-Rudy 1 cardiac model in large two- and three-dimensional domains and discuss the implications of our results for understanding the initiation of arrhythmias.

  20. Beyond Compassion: Children of Sex Workers in Kolkata's Sonagachi

    ERIC Educational Resources Information Center

    Sircar, Oishik; Dutta, Debolina

    2011-01-01

    In 2005, children of sex workers from Kolkata's Sonagachi red-light district formed their own collective, Amra Padatik ("We are Foot Soldiers"), to work for gaining dignity for their mothers and claiming their own rights as children of sex workers. In this article the authors speak to AP's founder members to demystify the culture of fear…

  1. Chromosomal and symbiotic relationships of rhizobia nodulating Medicago truncatula and M. laciniata.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    MultiLocus Sequence Typing (MLST) is a sequence-based method used to characterize bacterial genomes. This method was used to examine the genetic structure of Medicago-nodulating rhizobia at the Amra site, which is located in an arid region of Tunisia. Here the annual medics M. laciniata and M. tru...

  2. "Requestioning" AIDS: An Ethical Reflection From 1993 to Today. Reflections on Claude Vandevyer's "Homosexuals and AIDS: A New Approach to the Illness" from Journal of Homosexuality 25(3).

    PubMed

    Lau, Travis

    2016-01-01

    This article serves as one of the supplementary pieces of this special issue on "Mapping Queer Bioethics," in which we take a solipsistic turn to "map" the Journal of Homosexuality itself. Here, the author examines the first feature-length article to address the relationship between HIV status and homosexuality. Lingering on both the temporal gap between the dawn of AIDS in American discourse and its inclusion in this journal, the author asks us to consider (in hindsight) such a delay bearing in mind queer theoretical projects of the present such as gay shame, stigma, and queer biopolitics. PMID:26642922

  3. Teaching and Learning in the Interactive Classroom

    ERIC Educational Resources Information Center

    Silverthorn, D. U.

    2006-01-01

    The Claude Bernard Distinguished Lectureship of the Teaching of Physiology Section is presented annually at the Experimental Biology meeting. The lectureship is named for Prof. Claude Bernard, the experimental physiologist who is credited with introducing the concept of homeostasis. The 2006 Claude Bernard Distinguished Lecture was given by Dr.…

  4. Teaching and learning in the interactive classroom.

    PubMed

    Silverthorn, D U

    2006-12-01

    The Claude Bernard Distinguished Lectureship of the Teaching of Physiology Section is presented annually at the Experimental Biology meeting. The lectureship is named for Prof. Claude Bernard, the experimental physiologist who is credited with introducing the concept of homeostasis. The 2006 Claude Bernard Distinguished Lecture was given by Dr. Dee U. Silverthorn from the University of Texas at Austin, TX. PMID:17108239

  5. Inspector General takes aim at PPS fraud. Interview by Jill Callahan Dennis.

    PubMed

    Kusserow, R

    1986-03-01

    Among the most talked-about sessions at AMRA's 1985 Annual Meeting was a presentation by the Department of Health and Human Services' Inspector General, Richard Kusserow. JAMRA went behind the scenes to talk with the Inspector General. In this interview, he describes his role in guarding against fraud, waste and abuse in HHS programs, and how his duties affect medical record practitioners. PMID:10311443

  6. Found Space in a Courtyard

    ERIC Educational Resources Information Center

    Curley, Kenneth

    1974-01-01

    Skyrocketing interest rates and soaring construction costs are taking their toll on college and university building programs. At St. Norbert College in De Pere, Wisconsin, plans are underway to recycle a residence hall for use as a library. (Author)

  7. Geodiversity characterization and assessment of the Morainic Amphitheatre of Rivoli -Avigliana (NW-Italy)

    NASA Astrophysics Data System (ADS)

    Giordano, Enrico; Lucchesi, Stefania; Perotti, Luigi; Giardino, Marco

    2014-05-01

    The concept of Geodiversity in its wide sense refers specifically to particular geosystems that are in themselves complex (e.g diverse) assemblages of bedrock, landform, and soil features. Therefore, geodiversity assessment is strictly related to landscape structure, whose studies are in the field of complex Physical Geography. Moreover, Geodiversity studies provide a fundamental base for geoconservation and environmental management in a holistic way. This is particularly true within complex geomorphological environments, where many intrinsic and extrinsic factors are interconnected. Various procedures has been already applied for the creation of geodiversity maps in different geomorphological context, but especially in wide areas with a large geodiversity of landforms. Pleistocene morainic amphitheatres of the Alpine piedmont regions are indeed particular and complex environments: not only for the geological and geomorphological points of view, but also for their relationships with biotic components and human life. The aim of this study is to carry out a geodiversity characterization of the Rivoli-Avigliana Morainic Amphitheatre (AMRA; NW Italy). The AMRA separates the lower Susa Valley from the middle course of the Sangone River; it is a set of low hills and depressions related to glacial pulsations aged between 750,000 and 12,000 years ago. Earth Sciences knowledge of the area has been compared to detailed field geomorphological and territorial data in order to determine qualitative and quantitative landscape parameters and to evaluate their validity for geodiversity assessment. A first qualitative characterization of the AMRA and an estimation of its geodiversity have been performed by means of geomorphological mapping and stratigraphic studies, including geomorphosites assessment for the same area. Then, geodiversity characterization and evaluation have been performed through the definition and application of quantitative parameters (landform energy, slope

  8. Chandra Adds to Story of the Way We Were

    NASA Astrophysics Data System (ADS)

    2003-05-01

    consisting of two pairs of stars, called HD 98800A and HD 98800B. These pairs, each of which is about an Earth-Sun distance apart, orbit each other at about the same distance as Pluto orbits the Sun. "Our X-ray results are fully consistent with other observations that show that accretion of matter from a disk in HD 98800A has dropped to a low level," said Kastner. "So Chandra has thrown new weight behind the evidence that any disk in this system has been greatly diminished or destroyed in ten million years, perhaps by the ongoing formation of planets or by the companion stars." The new X-ray technique for studying disks around stars relies on the ability of Chandra's spectrometers to measure the energies of individual X-rays very precisely. By comparing the number of X-rays emitted by hot gas at specific energies from ions such as oxygen and neon, the temperature and density of particles can be determined. This new technique will help astronomers to distinguish between an accretion disk and a stellar corona as the origin of intense X-ray emission from a young star. Other members of the research team are David Huenemoerder, Norbert Schulz, and Claude Canizares from the Massachusetts Institute of Technology, and David Weintraub from Vanderbilt University. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program, and TRW, Inc., Redondo Beach, Calif., is the prime contractor for the spacecraft. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, Mass., for the Office of Space Science at NASA Headquarters, Washington. The image and additional information are available at: http://chandra.harvard.edu and http://chandra.nasa.gov

  9. A brief description about the fathers of computer and information sciences

    NASA Astrophysics Data System (ADS)

    Khan, Majid; Shah, Tariq; Shahab, Ali

    2015-03-01

    In this article, we are mainly presenting a tribute to the fathers of computer and information sciences, George Boole and Claude Elwood Shannon with their hardships and achievements. This piece of writing also elaborates the applications of George Boole's and Claude Shannon's works in different disciplines.

  10. Within the Shadows.

    ERIC Educational Resources Information Center

    Griffin, Noah

    1989-01-01

    Discusses why Black inventors historically were not recognized by society and the consequences of this discrimination. Covers the following inventors who defied the odds and beat the stereotype to invent important items: (1) Norbert Rillieux; (2) Jan Ernst Matzeliger; (3) Granville T. Woods; and (4) Garrett A. Morgan. (JS)

  11. Revista de Documentacao de Estudos em Linguistica Teorica e Aplicada (DELTA): Novos Estudos em Gamatica Gerativa (Journal of Documentary Studies in Theoretical and Applied Linguistics [DELTA]: New Studies in Generative Grammar).

    ERIC Educational Resources Information Center

    Revista de Documentacao de Estudos em Linguistica Teorica e Aplicada, 2000

    2000-01-01

    This issue contains the following articles: "Resumption and Last Resort" (Joseph Aoun); "Existentials, A-Chains, and Reconstruction" (Norbert Hornstein); "How Long Was the Nineteenth Century" (David Lightfoot); "Formal Features and Parameter Setting: A View From Portuguese Past Participles and Romance Future Tenses" (Lucia Lobata); "Revisiting…

  12. "I Couldn't Wait for the Day": Young Workers' Reflections on Education during the Transition to Work in the 1960s. CLMS Working Paper.

    ERIC Educational Resources Information Center

    Goodwin, John; O'Connor, Henrietta

    Researchers analyzed 500 never-before-analyzed interviews from a study conducted by Norbert Elias and other researchers at University of Leicester in 1962, which was one of the first studies of the transition from school to work. The Elias study explored how young people in England experienced work and adjusted their lives to the work role. All of…

  13. Configurations of Activity: From the Coupling of Individual Actions to the Emergence of Collective Activity. A Study of Mathematics Teaching Situation in Primary School

    ERIC Educational Resources Information Center

    Veyrunes, Philippe; Gal-Petitfaux, Nathalie; Durand, Marc

    2009-01-01

    This article presents and uses the notion of configuration of activity, which extends the Norbert Elias's original concept of social configuration based on the study and analysis of individual and collective activity. Although this concept embraces all types of social activities, in the present study the authors used it to describe and analyse…

  14. "Una Communita" Poco Nota della Communicazione non Verbale: Come Communicano il Direttore e l'Orchestra (A Little Known "Community" of Nonverbal Communication: How the Conductor and Orchestra Communicate).

    ERIC Educational Resources Information Center

    Leonardi, Magda Farago

    1992-01-01

    Examines how conductors and orchestras communicate. Communication is essentially nonverbal. Conductors use gestures, gaze, facial expression, nods and posture to deliver their message. Norbert Weiner's Cybernetic Theory of human communication is seen as a means of analyzing precisely how this musical communication takes place. (16 references) (LET)

  15. Identifying Configurations of Higher Education: Reflections on Concepts That Compare Complex Cultural Settings

    ERIC Educational Resources Information Center

    Alheit, Peter

    2013-01-01

    This paper examines the idea of qualitative comparing in order to create a "heuristic concept" that will enable relational structures to be examined, drawing on the sociological tradition founded by Norbert Elias. Subsequently, an empirical research example -- the comparison of three "mentality spaces" in post-socialist…

  16. Bilingual Competence and Bilingual Proficiency in Child Development

    ERIC Educational Resources Information Center

    Francis, Norbert

    2011-01-01

    When two or more languages are part of a child's world, we are presented with a rich opportunity to learn something about language in general and about how the mind works. In this book, Norbert Francis examines the development of bilingual proficiency and the different kinds of competence that come together in making up its component parts. In…

  17. 77 FR 4881 - Commercial Driver's license (CDL) Standards; Rotel North American Tours, LLC; Application for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ... the complete Privacy Act Statement in the Federal Register published on December 29, 2010 (75 FR 82133... drivers with German CDLs (75 FR 45200). Further information about past Rotel exemption requests and..., Karl-Heinz Schmitz, Josef Stockinger, Josef Vogl, Klaus Weber, Markus W lfl, Norbert Zechmesiter...

  18. Great Help for Older Americans | NIH MedlinePlus the Magazine

    MedlinePlus

    ... Falls and Older Adults Great Help for Older Americans Past Issues / Winter 2014 Table of Contents Click ... prevent or delay disability. Claude D. Pepper Older American Independence Centers (OAICs) University of California San Francisco ...

  19. Preventing Falls: Great Help for Older Americans

    MedlinePlus

    ... that may prevent or delay disability. Claude D. Pepper Older American Independence Centers (OAICs) University of California ... Wake Forest University P.I. Stephen Kritchevsky, PhD Pepper Coordinating Center Kevin High, MD University of Florida ...

  20. Libraries in Virginia: MedlinePlus

    MedlinePlus

    ... this page: https://medlineplus.gov/libraries/virginia.html Libraries in Virginia To use the sharing features on ... of Virginia Health System Claude Moore Health Sciences Library 1350 Jefferson Park Avenue, PO Box 800722 Charlottesville, ...

  1. Out of a creative jumble of ideas in the middle of last Century: Wiener, interdisciplinarity, and all that.

    PubMed

    Montagnini, Leone; Tabacchi, Marco Elio; Termini, Settimo

    2016-01-01

    Is Biophysics an interdisciplinary science? In order to answer this rhetorical question, it can be useful to look back at history of disciplines, as well as that of the scientific institutions helping their development. In this contribution some aspects of the unusual hodgepodge of concepts involving Biophysics, the legacy of Cybernetics, cognitive science and the central figure of Norbert Wiener are presented and discussed. PMID:26058742

  2. A Weather Analysis System for the Baja California Peninsula: Tropical Cyclone Season of 2008

    NASA Astrophysics Data System (ADS)

    Farfán, L. M.

    2009-05-01

    General characteristics of tropical weather systems are documented on a real-time basis. This study covers the warm season of 2008, from May through November, and includes observations from satellite imagery as well as reports from a rain-gauge network. During this season, the basin had 16 tropical storms and three of them made landfall in the Baja California peninsula, in northwestern Mexico. Tropical storm Julio developed in August and tropical storm Lowell made landfall in mid-September. Norbert, in early October, was the most intense hurricane of the season with strong winds and heavy rainfall that caused significant damage to the infrastructure in the southern peninsula. By the next day, the system moved over the mainland, causing major flooding in Sinaloa, Sonora, and Chihuahua. By request of the Baja California government, a meteorological perspective associated with the structure, intensity, and motion of Hurricane Norbert was presented. This consisted of high-resolution satellite imagery used to explain the spatial and temporal patterns of convection. This material provided an integral analysis of Norbert's behavior during its approach and passage over land, and it was one element, used by emergency managers, to determine the extent of the affected areas.

  3. Thermodynamic design of natural gas liquefaction cycles for offshore application

    NASA Astrophysics Data System (ADS)

    Chang, Ho-Myung; Lim, Hye Su; Choe, Kun Hyung

    2014-09-01

    A thermodynamic study is carried out for natural gas liquefaction cycles applicable to offshore floating plants, as partial efforts of an ongoing governmental project in Korea. For offshore liquefaction, the most suitable cycle may be different from the on-land LNG processes under operation, because compactness and simple operation are important as well as thermodynamic efficiency. As a turbine-based cycle, closed Claude cycle is proposed to use NG (natural gas) itself as refrigerant. The optimal condition for NG Claude cycle is determined with a process simulator (Aspen HYSYS), and the results are compared with fully-developed C3-MR (propane pre-cooled mixed refrigerant) JT cycles and various N2 (nitrogen) Brayton cycles in terms of efficiency and compactness. The newly proposed NG Claude cycle could be a good candidate for offshore LNG processes.

  4. Simplified Helium Refrigerator Cycle Analysis Using the `Carnot Step'

    SciTech Connect

    P. Knudsen; V. Ganni

    2006-05-01

    An analysis of the Claude form of an idealized helium liquefier for the minimum input work reveals the ''Carnot Step'' for helium refrigerator cycles. As the ''Carnot Step'' for a multi-stage polytropic compression process consists of equal pressure ratio stages; similarly for an idealized helium liquefier the ''Carnot Step'' consists of equal temperature ratio stages for a given number of expansion stages. This paper presents the analytical basis and some useful equations for the preliminary examination of existing and new Claude helium refrigeration cycles.

  5. Federal Drug Law Enforcement and Interdiction. Hearing before the Select Committee on Narcotics Abuse and Control. House of Representatives, Ninety-Eighth Congress, Second Session, May 22, 1984.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Narcotics Abuse and Control.

    This document contains testimony and prepared statements from the Congressional hearing on federal drug law enforcement. Statements are given from Congressman Claude Pepper, the staff director of the National Narcotics Border Interdiction System (NNBIS), an administrator from the Drug Enforcement Administration (DEA), a commissioner from the…

  6. Native Sons: A Critical Study of Twentieth-Century Negro American Authors.

    ERIC Educational Resources Information Center

    Margolies, Edward

    This analysis of 20th-century Negro literature contains chapters discussing 16 authors: (1) "The First Forty Years: 1900-1940," including W. E. B. DuBois, Charles W. Chesnutt, James W. Johnson, Paul L. Dunbar, Langston Hughes, Jean Toomer, Claude McKay, and Countee Cullen; (2) "Migration: William Attaway and 'Blood on the Forge'"; (3) "Richard…

  7. 76 FR 69281 - Notice of Availability of the Record of Decision for the Over The River TM

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... Bureau of Land Management Notice of Availability of the Record of Decision for the Over The River \\TM... construction, display, and removal of the proposed Over The River \\TM\\ Art Project (OTR). The ROD is effective... Jeanne-Claude, proposes to install a work of art, titled Over The River \\TM\\, on Federal, state...

  8. A Monet Garden Installation: A Momentary Gift of Art.

    ERIC Educational Resources Information Center

    McGonigle, Kathleen

    2002-01-01

    Discusses art lessons where students created a three-dimensional rendering of Claude Monet's gardens using the Impressionist style. Focused on teaching students about art history, Impressionistic art, and installation of art. Addresses the goals of the lesson and the process of creating the art. (CMK)

  9. Integrate the Arts. Monet's Garden Pops Up!

    ERIC Educational Resources Information Center

    Parks, Mary

    1996-01-01

    This article outlines the steps in an art activity on the elements of landscapes and touches on the topic of perspective. In the activity students create three-dimensional secret gardens of their own out of construction paper. The activity is based on Claude Monet's painting and his garden in Giverny (Normandy, France). (SM)

  10. Shades of Monet.

    ERIC Educational Resources Information Center

    Baber, Bonnie

    1999-01-01

    Presents an art lesson for elementary students using painter Claude Monet as an introduction to Impressionism. Discusses Monet and his artwork. Explains that the students copy Monet's painting "The House of Parliament, Sunset" in order to draw the contour or outline of the buildings. (CMK)

  11. Monet Flowers: How My Summer Trip Inspired a Garden of Art...

    ERIC Educational Resources Information Center

    Dunay, Cecelia M.

    1998-01-01

    Describes a lesson plan designed for first- through fifth-grade students in which they made their own impressionist-style artworks. Explains that the lesson was introduced with a discussion on Claude Monet, his many art prints, and the impressionist genre. Explores the differences between things of nature and man-made objects. Notes materials and…

  12. Repetition Makes an Impression.

    ERIC Educational Resources Information Center

    Slemmer, Paula M.

    1999-01-01

    Describes two art projects, one for second-grade students and the other for third-grade students, inspired by the artwork of Claude Monet. The second-graders created leaf prints to frame the Impressionist autumn trees they painted, while the third-grade lesson centered around the videotape "Linnea in Monet's Garden." (CMK)

  13. The XIIIth International Physiological Congress in Boston in 1929: American Physiology Comes of Age

    ERIC Educational Resources Information Center

    Rall, Jack A.

    2016-01-01

    In the 19th century, the concept of experimental physiology originated in France with Claude Bernard, evolved in Germany stimulated by the teaching of Carl Ludwig, and later spread to Britain and then to the United States. The goal was to develop a physicochemical understanding of physiological phenomena. The first International Physiological…

  14. Linking Stereotype Threat and Anxiety

    ERIC Educational Resources Information Center

    Osborne, Jason W.

    2007-01-01

    Claude Steele's stereotype threat hypothesis has attracted significant attention in recent years. This study tested one of the main tenets of his theory--that stereotype threat serves to increase individual anxiety levels, thus hurting performance--using real-time measures of physiological arousal. Subjects were randomly assigned to either high or…

  15. Elder Abuse. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains testimony and prepared statements from a Congressional hearing called to examine the issue of elder abuse. Chairman Claude Pepper's opening statement discusses the horror of elder abuse and calls for federal legislation, similar to the child abuse legislation, for combating elder abuse. Elder abuse is defined as physical…

  16. Perfectible Apes in Decadent Cultures: Rousseau's Anthropology Revisited

    ERIC Educational Resources Information Center

    Wokler, Robert

    1978-01-01

    Briefly discusses the views of Claude Levi-Strauss and Robert Ardrey who cite Rousseau as a personal influence even though they hold opposing anthropological ideals. The author claims that this situation is due to misinterpretations of Rousseau's work. An interpretation of Rousseau's anthropology is given reconciling the differences. (BC)

  17. Coding and Quantization in Communications and Microeconomics

    ERIC Educational Resources Information Center

    Xu, Yun

    2013-01-01

    Since information theory was developed by Claude E. Shannon, in addition to its primary role in communications and networking, it has broadened to find applications in many other areas of science and technology, such as microeconomics, statistics, and neuroscience. This thesis investigates the application of information theoretic viewpoints to two…

  18. Gender, Stereotype Threat, and Anxiety: Psychophysiological and Cognitive Evidence

    ERIC Educational Resources Information Center

    Osborne, Jason W.

    2006-01-01

    Introduction: Claude Steele's stereotype threat hypothesis proposed that negative group stereotypes increase individual anxiety levels, hurting performance. However, the role of anxiety in stereotype threat has not been fully explored. This study examined the hypothesis that experimental manipulation of stereotype threat would influence real-time…

  19. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  20. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  1. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  2. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  3. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  4. The Attempted Dismantling of the Medicare Home Care Benefit. A Report by the Chairman of the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session.

    ERIC Educational Resources Information Center

    Pepper, Claude

    This document presents Congressman Claude Pepper's report on the Medicare Home Care Benefit. Section I traces the history of home health care in the United States. Section II offers statistics and general background information about older Americans and Medicare. The beginning of the Medicare home care benefit and its present operation are…

  5. Long-Term Care: Need for a National Policy. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session (December 15, 1983, San Francisco, California).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains transcripts of witness testimony and prepared statements from the Congressional hearing called to review the need for a national health care policy for long-term care. Opening statements are presented from committee chairman Claude Pepper and from Representatives Sala Burton and Barbara Boxer. Testmonies are presented from…

  6. Abuses in Guardianship of the Elderly and Infirm: A National Disgrace. A Briefing by the Chairman of the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, One Hundredth Congress, First Session (September 25, 1987).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document presents a briefing by Representative Claude Pepper on the abuses in guardianship of the elderly and infirm, and testimony from witnesses at the Congressional hearing called to examine the issue of guardianship abuse. The opening statement of Representative Pepper and a prepared statement of Representative Helen Delich Bentley are…

  7. Long-Term Care Insurance: Coverage Varies Widely in a Developing Market. Report to the Chairman, Subcommittee on Health and Long-Term Care, Select Committeee on Aging, House of Representatives.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC. Div. of Human Resources.

    In response to a request by Congressman Claude Pepper, the General Accounting Office (GAO) conducted a study to examine the private long-term care insurance market. The GAO analyzed the premiums, benefits, and limitations of 33 policies offered by 25 insurers in 1986. The GAO assessed the potential for abuse in this market by surveying state…

  8. Alcohol and the Elderly. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session (June 10, 1983, Astoria, N.Y.).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    The proceedings of the Congressional hearing on alcohol and the elderly are presented. Following introductory statements by the committee chairman, Senator Claude Pepper, and Representatives Mario Biaggi and Geraldine Ferraro, the briefing paper, "Crisis in Health Care Part 2: Alcoholism," prepared by the subcommittee staff is presented. Issues…

  9. Ability Is Ageless. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document presents the text of a hearing on the relationship of ability to age, in reference to removing age caps so that age will be irrelevent to getting and keeping a job. Statements by Representatives Ron Wyden, Claude Pepper, Ralph Regula, Bill Schuette, Jim Lightfoot, Ike Skelton, George Wortley, and Don Bonker are included. Testimony by…

  10. HMO's and Medicare: Problems in the Oversight of a Promising Partnership. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains witness testimonies and prepared statements from the Congressional hearing called to examine problems in the partnership of Medicare and Health Maintenance Organizations (HMO's). Opening statements are included from committee chairman Claude Pepper and from Representative Lawrence J. Smith. Two panels of witnesses address…

  11. Catastrophic Health Insurance: The Tennessee Perspective. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session (Chattanooga, Tennessee).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains witnesses' testimonies and prepared statements from the Congressional hearing held in Chattanooga, Tennessee to gain that state's perspective on catastrophic health insurance. Opening statements are included from Representatives Marilyn Lloyd and Claude Pepper. Two panels of witnesses provide testimony. The first panel,…

  12. Hearing on H.R. 670, The School Completion and Incentives Act. Hearing before the Subcommittee on Elementary, Secondary, and Vocational Education of the Committee on Education and Labor. House of Representatives, One Hundred First Congress, First Session (Miami, Florida).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Education and Labor.

    This document presents witness testimony and prepared statements from the Congressional hearing. Statements are included from Representatives Claude Pepper, Carl Perkins, Charles Hayes, and Nick Rahall. Witnesses providing testimony include: (1) Joseph Fernandez, Superintendent of Dade County Public Schools, Florida; (2) Nan Rich, who describes…

  13. A Course Connecting Astronomy to Art, History, and Literature

    ERIC Educational Resources Information Center

    Olson, Don

    2015-01-01

    For the past 20 years the author has taught an Honors College course combining astronomy and the humanities. The purpose of this note is to give examples of methods that can be adapted to classroom use for topics including night sky paintings by Vincent van Gogh, Edvard Munch, and Claude Monet, historical events influenced by astronomical factors,…

  14. 76 FR 11561 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... Schultz No. 127, Colonia San Rafael, Delegacion Cuauhtemoc, Mexico City, Distrito Federal C.P. 06470.... MARTINEZ GOMEZ, Milton Geovany; DOB 11 Jul 1972; POB Muzo, Boyaca, Colombia; Cedula No. 11186154 (Colombia.... LE CLAUDE, S.A. DE C.V., Calle Miguel E. Shultz No. 127, Colonia San Rafael, Delegacion...

  15. Monet's Reflections

    ERIC Educational Resources Information Center

    Petrovich-Cheney, Laura

    2007-01-01

    From 1899 until his death in 1926, Claude Monet painted a series of watercolor landscapes of his water lily garden and Japanese bridge in Giverny, France. Monet eventually abandoned the banks entirely as subject matter and concentrated solely on the water. These paintings, particularly "The Water Lilies," show a surface in which the shimmering…

  16. Haitian Art: Exploring Cultural Identity. Instructional Resources.

    ERIC Educational Resources Information Center

    Hayes, Anne Marie; Robinson, Michelle

    2001-01-01

    Presents an instructional resource on Haitian art and provides historical information on Haiti. Features four artists: (1) Hector Hyppolite; (2) Edouard Duval-Carrie; (3) Paul Claude Gardere; and (4) Bien-Aime Sylvain. Includes background information on each artist, learning activities, and reproductions of their artwork. (CMK)

  17. Kindergarten Monets

    ERIC Educational Resources Information Center

    Dionne, Suzanne

    2012-01-01

    Integrating art with literature and science enhances students' learning and retention. Whenever possible, the introduction of the author's art lessons include a relevant artist, such as Claude Monet. In this article, kindergartners paint a pond and learn how to make water lilies using colored tissue-paper squares. (Contains 4 resources.)

  18. Workers' Attitudes to Technical Change: An Integrated Survey of Research. Industrial Relations Aspects of Manpower Policy 2.

    ERIC Educational Resources Information Center

    Touraine, Alain; And Others

    Methods for encouraging positive worker attitude and behavior toward change were examined to provide a basis for re-evaluation of current policies and programs relating to introduction of technological changes. The literature reviewed is presented in sections of: (1) "The Worker and the Occupational System," by Claude Durand, (2) "The Worker and…

  19. On the Shoulders of Giants: From Boole to Shannon to Taube: The Origins and Development of Computerized Information from the Mid-19th Century to the Present.

    ERIC Educational Resources Information Center

    Smith, Elizabeth S.

    1993-01-01

    Describes the evolution of computerized information storage and retrieval from its mid-nineteenth century beginnings in theoretical works on logic by George Boole, to the applications of Boole's logic to switching circuits by Claude Shannon in the 1930s, to the development of coordinate indexing by Mortimer Taube in the 1940s and 1950s. (Contains…

  20. If Only Clairaut Had Dynamic Geometric Tools

    ERIC Educational Resources Information Center

    Chang, Hyewon; Reys, Barbara J.

    2013-01-01

    Geometry is a major area of study in middle school mathematics, yet middle school and secondary students have difficulty learning important geometric concepts. This article considers Alexis-Claude Clairaut's approach that emphasizes engaging student curiosity about key ideas and theorems instead of directly teaching theorems before their…

  1. Harlem, History, and First-Year Composition: Reconstructing the Harlem of the 1930s through Multiple Research Methods

    ERIC Educational Resources Information Center

    Wilson, James

    2003-01-01

    Describing the Harlem Riot of 1935, black author and poet Claude McKay wrote, "On Tuesday the crowds went crazy like the remnants of a defeated, abandoned, and hungry army. Their rioting was the gesture of despair of a bewildered, baffled, and disillusioned people". By nearly all accounts, the riot marks the historical end of the Harlem…

  2. Observatoire de Lyon

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    The Observatoire de Lyon is a laboratory of Université Claude Bernard Lyon1, under the authority of the INSTITUT NATIONAL DES SCIENCES DE L'UNIVERS. It constitutes the Centre de Recherche astrophysique de Lyon together with the astrophysics group of the École Normale Supérieure de Lyon....

  3. APS at 125: A Look Back at the Founding of the American Physiological Society

    ERIC Educational Resources Information Center

    Ryan, Kathy L.

    2013-01-01

    Early efforts in physiological research in the United States were produced by lone investigators working in laboratories funded by their own medical practices. In Europe, however, Claude Bernard and Carl Ludwig produced a new model of scientific research laboratories funded by the state that sought to develop the pursuit of biomedical research as…

  4. Auf De Suche Nach Der Guten Schule: In Search of a Great School

    ERIC Educational Resources Information Center

    Chirichello, Michael

    2009-01-01

    This module is the result of the author Michael Chirichello's visit to Luxembourg in 2008. He includes the contact information here for the Atert-Lycee Redange principal or director: Claude Boever, Directeur, email: directeur@alr.lu This publication aligns with the Interstate School Leaders Licensure Consortium (ISSLC) Standard 1: "An…

  5. Faith, Friendship and Learning: Intercultural Communication in the Republic of Letters

    ERIC Educational Resources Information Center

    Austin, Kenneth; Anderson, Wendy

    2010-01-01

    This article uses the renowned antiquarian Nicolas-Claude Fabri de Peiresc (1580-1637) as a case study to examine the intellectual and religious culture of the early seventeenth century. In particular, using his extensive correspondence, it investigates the manner in which the exchange of letters could be used to reinforce the identity of one…

  6. Show Me the Monet!...and Other Artists.

    ERIC Educational Resources Information Center

    Roman, Michele

    1999-01-01

    Describes a project designed to advertise art history where eighth-grade students painted the classroom door windows throughout their school recreating famous classic paintings from various artists, such as Claude Monet or Vincent van Gogh. Explains that the students learned about different artistic styles and exhibited a great deal of pride in…

  7. Landscapes. Artists' Workshop Series.

    ERIC Educational Resources Information Center

    King, Penny; Roundhill, Clare

    This instructional resource, designed to be used by and with elementary level students, provides inspiration for landscape painting by presenting the work of six different artists. These include: "Fuji in Clear Weather" (Katsushika Hokusai, 1823-29); "The Tree of Life" (Gustav Klimt, c. 1905-1909); "The Waterlily Pond" (Claude Monet, 1899);…

  8. Safety and Efficacy of Over-the-Counter Drug Use by the Elderly. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains the prepared statements and panel testimony from the Congressional hearing on over-the-counter (OTC) drug use by the elderly. Opening statements are given by Representatives Claude Pepper (chairman), Ralph Regula, Mary Rose Oakar, Michael Bilirakis, Tom Lantos, and Hal Daub. Topics which are covered include the incidence and…

  9. Hearings Before the Select Committee on Nutrition and Human Needs of the United States Senate, Ninety-Second Congress, Second Session on Nutrition and Human Needs. Part 2--Nutritional Needs of Nation's Older Americans. Hearings Held Washington, D.C., June 14, 1972.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Select Committee on Nutrition and Human Needs.

    This hearing before the Senate Select Committee on Nutrition and Human Needs began with opening statements by a number of senators. Following this, statements were made by a number of witnesses, including Hon. Claude Pepper, a U.S. Representative from the Eleventh District of the State of Florida; Dr. Jean Mayer, professor of nutrition, Harvard…

  10. It's a Wrap! A Study of Installations.

    ERIC Educational Resources Information Center

    Buck, Susan

    2002-01-01

    Describes an art project for junior and senior high school students called the wrapped chair project where students wrapped chairs using torn sheets in the style of artists, Christo Javacheff and Jeanne-Claude de-Guillebon. Explains that students created thumbnail sketches and drew their finished drawing in either charcoal or chalk. (CMK)

  11. Papers in Language Policy from the Language Policy Conference (Roskilde, Denmark, January 29, 1996). ROLIG Papir No. 56.

    ERIC Educational Resources Information Center

    Bakmand, Bente, Ed.; And Others

    The papers included in this issue are from a conference on language policy. The papers are: "Why Promote European Multilingualism? French Experience" (Claude Truchot); "German Attitudes to European Language Policy" (Ulrich Ammon); "Minority Language Rights in Contemporary Europe" (Tove Skutnabb-Kangas); "Teacher Identities in Britain and Denmark…

  12. Modern Impressions

    ERIC Educational Resources Information Center

    Simkus, Joyce

    2010-01-01

    Claude Monet and the Impressionists were the forward thinkers and painters of their time. They used quick brushstrokes and a rapid pace to capture lively outdoor scenes. Inspired by the colors and shadows revealed by sunlight, the Impressionists typically worked outside, without many preliminary sketches or drafts. This was in direct contrast to…

  13. [The sense of the senseless, psychoanalytic aspects of delusion in psychosis].

    PubMed

    Chaperot, Christophe

    2011-01-01

    The psychoanalytic approach to delusion in psychosis leads us to examine the function of a "furrow". It is necessary to remain in the furrow in order not to become delusional. References to Sigmund Freud, Jacques Lacan, Mélanie Klein and Jean-Claude Maleval enlighten us as to the origin and the function of delusion as an attempt to give meaning. PMID:21416882

  14. Retreat to Eden: Time and the Cosmos in Monet's Images of Giverny.

    ERIC Educational Resources Information Center

    Call, Michael

    1997-01-01

    Attempts to explain Claude Monet's obsession with water lilies in the last 25 years of his life through an interdisciplinary approach combining ideas from the history of landscape design, social history, and anthropology. Offers Monet's gardens at Giverny (France), his series paintings, and the railroad as some possible influences on his painting.…

  15. Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (13th, Quebec, Canada, March 25-26, 1999).

    ERIC Educational Resources Information Center

    Kavanagh, Eric, Ed.

    Papers on language research in this volume include the following: Pour une comparaison des voyelles nasals du Quebec et du Haut-Jura: observations, methodologie et outils infomatiques (A Comparison of Quebec and Haut-Jura's Nasal Vowels: Observations, Methodologies, and Instrumentation) (Vincent Arnaud and Claude Paradis); Le negociation du sens…

  16. A Physiologist's View of Homeostasis

    ERIC Educational Resources Information Center

    Modell, Harold; Cliff, William; Michael, Joel; McFarland, Jenny; Wenderoth, Mary Pat; Wright, Ann

    2015-01-01

    Homeostasis is a core concept necessary for understanding the many regulatory mechanisms in physiology. Claude Bernard originally proposed the concept of the constancy of the "milieu interieur," but his discussion was rather abstract. Walter Cannon introduced the term "homeostasis" and expanded Bernard's notion of…

  17. Promoting Learning for Culturally and Linguistically Diverse Students. Classroom Applications from Contemporary Research.

    ERIC Educational Resources Information Center

    Gersten, Russell M.; Jimenez, Robert T.

    This collection of essays is designed to help teachers of linguistically and culturally diverse students address their students' needs effectively. Essays include: "A Balanced Approach to Early Spanish Literacy Instruction" (Claude Goldenberg); "Language and Preliteracy Development of English as a Second Language Learners in Early Childhood…

  18. STS-103 crew signs autographs after presentation at KSC

    NASA Technical Reports Server (NTRS)

    2000-01-01

    After a presentation at KSC for employees and VIPs about their mission, STS-103 crew members sign autographs. From left are Mission Specialists Claude Nicollier and Jean-Francois Clervoy, Pilot Scott Kelly, and Mission Specialist Steven Smith. The STS- 103 mission, servicing the Hubble Space Telescope, included three space walks. STS-103 launched Dec. 19, 1999, and landed Dec. 27, 1999.

  19. STS-103 crew signs autographs after presentation at KSC

    NASA Technical Reports Server (NTRS)

    2000-01-01

    After a presentation at KSC for employees and VIPs about their mission, STS-103 crew members sign autographs. From left are Mission Specialist Steven Smith, Pilot Scott Kelly, and Mission Specialists Jean-Francois Clervoy and Claude Nicollier. The STS- 103 mission, servicing the Hubble Space Telescope, included three space walks. STS-103 launched Dec. 19, 1999, and landed Dec. 27, 1999.

  20. Sartre: A Collection of Critical Essays. Twentieth Century Views Series.

    ERIC Educational Resources Information Center

    Kern, Edith, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Edith Kern, Claude-Edmonde Magny, Henri Peyre, Kenneth Douglas, Edmund Wilson, Theophil Spoerri, Jacques Guicharnaud, Eric Bentley, Robert Champigny, Oreste F. Pucciani, Frederic Jameson, Rene Girard, Guido…

  1. Evolution of an Educator: Lessons Learned and Challenges Ahead

    ERIC Educational Resources Information Center

    Modell, Harold I.

    2004-01-01

    In selecting a Claude Bernard Distinguished Lecturer, the Teaching Section looks for an individual who has made major contributions to physiology education. Dr. Harold Modell has certainly earned this honor. Harold has an undergraduate degree from the University of Minnesota, a Masters in biomedical engineering from Iowa State, and, continuing the…

  2. Judge Rules Plagiarism-Detection Tool Falls under "Fair Use"

    ERIC Educational Resources Information Center

    Young, Jeffrey R.

    2008-01-01

    Judge Claude M. Hilton, of the U.S. District Court in Alexandria, Virginia, in March found that scanning the student papers for the purpose of detecting plagiarism is a "highly transformative" use that falls under the fair-use provision of copyright law. He ruled that the company "makes no use of any work's particular expressive or creative…

  3. Travaux Neuchatelois de linguistique (Neuchatel Working Papers in Linguistics).

    ERIC Educational Resources Information Center

    Neuchatel Univ. (Switzerland). Inst. de Linguistique.

    This collection of working papers in linguistics includes four works. "Autour de la racine indo-europeenne 'pet-' ('voler') (pour servir a l'histoire des faits latins)" ("Concerning the Indo-European Root 'Pet-' ('To Fly') (To Serve as an Example of Latin Facts)" by Claude Sandoz looks at the Latin manifestations of the root and illustrates the…

  4. Videotape Recording of Narcotic Addicts in Group Therapy: The Analysis of Communicational and Interactive Behavior.

    ERIC Educational Resources Information Center

    Soloway, Irv

    An approach to the study of drug sub-culture groups and a model for predictive research in the identification and isolation of heroin addicts are developed in this thesis. The basic methodologies employed are the linguistic methods of Kenneth Pike and Claude Levi-Strauss for use in the analysis of social phenomena. Communicative mechanisms by…

  5. Monet's Water Lilies

    ERIC Educational Resources Information Center

    Maroni, Michelle

    2006-01-01

    Students love the colors of Monet prints. The sunny yellows, misty blues, soft lavenders, and outrageous oranges. Using this as inspiration, Michelle Maroni wanted her students to discover new painting techniques and ways of planning a composition with more spontaneity. In this article, she describes how she introduced Claude Monet to her students…

  6. Panning for Gold: Utility of the World Wide Web for Metadata and Authority Control in Special Collections.

    ERIC Educational Resources Information Center

    Ellero, Nadine P.

    2002-01-01

    Describes the use of the World Wide Web as a name authority resource and tool for special collections' analytic-level cataloging, based on experiences at The Claude Moore Health Sciences Library. Highlights include primary documents and metadata; authority control and the Web as authority source information; and future possibilities. (Author/LRW)

  7. Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (12th, Quebec City, Canada, March 26-27, 1998).

    ERIC Educational Resources Information Center

    Boissonneault, Chantal, Ed.

    Papers on language research include: "L'expression de l'opposition en Latin" ("The Expression of Opposition in Latin" (Claude Begin); "Le francais de l'Abitibi: characteristiques phonetiques et origine socio-geographique des locuteurs" ("The French of Abitibi: Phonetic Characteristics and Socio-Geographic Origin of Speakers") (Chantal…

  8. Charting a Global Future for Education in Physiology

    ERIC Educational Resources Information Center

    Sefton, Ann J.

    2005-01-01

    The 2005 Claude Bernard Distinguished Lecture was presented at the XXXV International Congress of Physiological Sciences (IUPS) in San Diego, CA, by Ann J. Sefton. Dr. Sefton is an Emeritus Professor of Physiology of the University of Sydney and co-Chair of the IUPS Education Committee. A full profile of Dr. Sefton is included in this issue's "The…

  9. Structural Reform in Higher Education Collective Bargaining. Proceedings of the Annual Conference of the National Center for the Study of Collective Bargaining in Higher Education and the Professions (12th, New York, New York, April 1984).

    ERIC Educational Resources Information Center

    Douglas, Joel M., Ed.

    Structural reform in higher education collective bargaining is examined in these conference proceedings, along with recent state bargaining legislation, and legal, union, and management views concerning sex discrimination in higher education. The 19 article topics and authors include: the problem of reshaping the fringe package (Claude Campbell);…

  10. Poststructuralism as Theory and Practice in the English Classroom. ERIC Digest.

    ERIC Educational Resources Information Center

    Bush, Harold K., Jr.

    This digest provides a historical review of some current literary theories and practices which developed from contemporary philosophy. Structuralism, associated with Ferdinand de Saussure and Claude Levi-Strauss, with a seemingly scientific view of language and culture posited a systemic "center" that organized and sustained an entire structure.…

  11. Chandra Discovers the X-ray Signature of a Powerful Wind from a Galactic Microquasar

    NASA Astrophysics Data System (ADS)

    2000-11-01

    NASA's Chandra X-ray Observatory has detected, for the first time in X rays, a stellar fingerprint known as a P Cygni profile--the distinctive spectral signature of a powerful wind produced by an object in space. The discovery reveals a 4.5-million-mile-per-hour wind coming from a highly compact pair of stars in our galaxy, report researchers from Penn State and the Massachusetts Institute of Technology in a paper they will present on 8 November 2000 during a meeting of the High-Energy Astrophysics Division of the American Astronomical Society in Honolulu, Hawaii. The paper also has been accepted for publication in The Astrophysical Journal Letters. "To our knowledge, these are the first P Cygni profiles reported in X rays," say researchers Niel Brandt, assistant professor of astronomy and astrophysics at Penn State, and Norbert S. Schulz, research scientist at the Massachusetts Institute of Technology. The team made the discovery during their first observation of a binary-star system with the Chandra X-ray Observatory, which was launched into space in July 1999. The system, known as Circinus X-1, is located about 20,000 light years from Earth in the constellation Circinus near the Southern Cross. It contains a super-dense neutron star in orbit around a normal fusion-burning star like our Sun. Although Circinus X-1 was discovered in 1971, many properties of this system remain mysterious because Circinus X-1 lies in the galactic plane where obscuring dust and gas have blocked its effective study in many wavelengths. The P Cygni spectral profile, previously detected primarily at ultraviolet and optical wavelengths but never before in X rays, is the textbook tool astronomers rely on for probing stellar winds. The profile looks like the outline of a roller coaster, with one really big hill and valley in the middle, on a data plot with velocity on one axis and the flow rate of photons per second on the other. It is named after the famous star P Cygni, in which such

  12. Quantum mechanical coherence, resonance, and mind

    SciTech Connect

    Stapp, H.P.

    1995-03-26

    Norbert Wiener and J.B.S. Haldane suggested during the early thirties that the profound changes in our conception of matter entailed by quantum theory opens the way for our thoughts, and other experiential or mind-like qualities, to play a role in nature that is causally interactive and effective, rather than purely epiphenomenal, as required by classical mechanics. The mathematical basis of this suggestion is described here, and it is then shown how, by giving mind this efficacious role in natural process, the classical character of our perceptions of the quantum universe can be seen to be a consequence of evolutionary pressures for the survival of the species.

  13. A-Train Data Depot (ATDD)

    NASA Technical Reports Server (NTRS)

    Smith, Peter M.; Kempler, Steven; Leptoukh, Gregory; Savtchenko, Andrey; Kummerer, Robert; Gopolan, Arun

    2008-01-01

    ATDD is a web based tool which provides collocated data and display products for a number of A-train instruments Cloudsat, Calipso, OMI, AIRS, MODIS, MLS, POLDER-3, and ECWMF model data. Products provided include Clouds, Aerosols, Water Vapor, Temperatures and trace gases. All input data is online and in HDF4, HDF5 format. Display products include curtain images, horizontal strips, line plot overlays, and GE kmz files. Sample products are shown for two type of events. Hurricane event, Norbert, Oct 8, 2008 and a dust storm event over the Arabian Sea, Nov 13-14, 2008.

  14. [The relationship between Bergson's philosophy and medicine].

    PubMed

    Kulczycki, J

    1994-01-01

    The relationship between Bergson's philosophy and medicine follows an outline of theoretical situation in philosophy in the second half of 19c. The former relationship is evident in Bergson's mind-body considerations and thoughts concerning philosophical importance of Claude Bernard's works and are of bilateral nature. Bergson criticized lokalization theory and psychophysical paralelism on the ground of the contemporary neurology and psychiatry. Conversely his ideas, particularly those concerning the nature of conscioiusness and aphasia were reflected in both psychopathology and neurology. Bergson perceives the philosophical importance of Claude Bernard primarily in his theoretical experimental bases for research in medicine and biology. The paper closes considering the importance of various conceptions of personality (including Bergson's) in philosophy of medicine and medical practice. PMID:11624858

  15. Painting a Data-Rich Picture

    ERIC Educational Resources Information Center

    Earl, Lorna; Katz, Steven

    2005-01-01

    Using data for school reform is like painting a series of pictures--pictures that are subtle and capture the nuances of the subject. This is a far cry from drawing stick figures or paint-by-numbers. Imagine the experiences of the French painter Claude Monet as he wandered through his garden at Giverny at different times of the day and year,…

  16. A Course Connecting Astronomy to Art, History, and Literature

    NASA Astrophysics Data System (ADS)

    Olson, Don

    2015-10-01

    For the past 20 years the author has taught an Honors College course combining astronomy and the humanities. The purpose of this note is to give examples of methods that can be adapted to classroom use for topics including night sky paintings by Vincent van Gogh, Edvard Munch, and Claude Monet, historical events influenced by astronomical factors, and literary references to the sky by authors including Chaucer, Shakespeare, and Walt Whitman.

  17. STS-46 crewmembers participate in Fixed Base (FB) SMS training at JSC

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, Pilot Andrew M. Allen hands Mission Specialist (MS) and Payload Commander (PLC) Jeffrey A. Hoffman checklists from middeck locker MF43E during training session in JSC's fixed base (FB) shuttle mission simulator (SMS) located in Mission Simulation and Training Facility Bldg 5. European Space Agency (ESA) MS Claude Nicollier outfitted with communications kit assembly headset (HDST) and equipment looks beyond Hoffman to the opposite side of the middeck.

  18. European Space Agency (ESA) Mission Specialist Nicollier trains in JSC's WETF

    NASA Technical Reports Server (NTRS)

    1987-01-01

    European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier (left) is briefed by Randall S. McDaniel on Space Shuttle extravehicular activity (EVA) tools and equipment prior to donning an extravehicular mobility unit and participating in an underwater EVA simulation in JSC's Weightless Environment Training Facility (WETF) Bldg 29 pool. Nicollier is holding the EMU mini workstation. Other equipment on the table includes EVA tool caddies and EVA crewmember safety tethers.

  19. Solar Sea Power Plants (SSPP): A critical review and survey

    NASA Technical Reports Server (NTRS)

    Strauss, A. M.

    1974-01-01

    An overview of technical and economic matters relating to the eventual success or failure of the SSPP concept is presented, with emphasis on the pollution and energy problems which the SSPP would serve to eliminate. Factors discussed include cost, mariculture possibilities, siting, legal limitations, design materials, mooring and anchoring, and the human element involved. Several alternative power systems are considered for incorporation into SSPP design, such as Nitinol power, Claude cycle, and closed cycle engine systems.

  20. STS-75 Payload Specialist Umberto Guidoni suits up

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 Payload Specialist Umberto Guidoni (right) chats with fellow crew member Mission Specialist Claude Nicollier during suitup activities in the Operations and Checkout Building. Guidoni represents the Italian Space Agency and is one of three international crew members assigned to STS-75. He and six fellow crew members will depart shortly for Launch Pad 39B, where the Space Shuttle Columbia awaits liftoff during a two-and-a-half- hour launch window opening at 3:18 p.m. EST.

  1. The Gates, 1979-2005

    ERIC Educational Resources Information Center

    School Arts: The Art Education Magazine for Teachers, 2005

    2005-01-01

    One art critic called it pure Despite the mixed reviews of Christo and Jeanne-Claude's temporary art installation in New York's Central Park, the public reaction to The Gates was largely positive.The Gates consisted of 7,500 orange PVC frames straddling the park's walkways that varied in widths from 5 1/2 feet to 18 feet. Eight-foot-long ripstop…

  2. Les etoiles qui ne veulent pas vieillir

    NASA Astrophysics Data System (ADS)

    Bonnet-Bidaud, J. M.

    1995-12-01

    Qu'est-ce qui fait courir Jean-Claude Pecker ? Ses travaux sur les atmospheres stellaires qu'il poursuit aujourd'hui ? Son combat pour les droits de l'homme, ou contre le sceau du secret qui pese encore sur la recherche fondamentale ? Tout a la fois. Pour cette figure emblematique de l'astrophysique francaise, aujourd'hui a la retraite, pas question de raccrocher les armes...

  3. [Hommage to M.L. Girard: gestation and birth of biochemistry in hospitals].

    PubMed

    Dreux, C

    1999-01-01

    Prof Claude Dreux pays hommage to Prof Maurice-Louis Girard and relates the gestation and the birth of biochemistry in hospitals. He successively evokes Hippocrates, Galen, Paracelsius, Robert Boyle, Nicolas Vauquelin, J.J. Von Scherer, J.F. Zeller, G.H. Esbach, Apollinaire Bouchardat, Georges Deniges, Paul Yvon, Ambard, Loiseleur, Leon Grimbert, Paul Fleury, Jean-Emile Courtois and last but not the least Maurice-Louis Girard. PMID:11625655

  4. [Alexis Carrell: the mystification ...].

    PubMed

    Vanderpooten, C

    1996-01-01

    Alexis Carrel is died in 1944. A half-century later, the most we know about his life comes from his widow. Pupil of the Jesuits, faith lost with Claude Bernard, recovered thanks to his wife, papers lefts to the Jesuits ..., all is well. Too beautiful edifying story to be true ... Details show that mystification trouble is in it. Who was, what thought exactly Carrel? Light may be shed only by an exhaustive study of his manuscripts and letters. PMID:11624869

  5. STS-26 Discovery, Orbiter Vehicle (OV) 103, OMS pod leak repair at KSC

    NASA Technical Reports Server (NTRS)

    1988-01-01

    At the Kennedy Space Center (KSC), Rockwell manufacturing engineering specialist Claude Willis (left) and Rockwell manufacturing supervisor George Gallagher begin installation of a 'clamshell' device in the left orbital maneuvering system (OMS) pod reaction control system (RCS) of Discovery, Orbiter Vehicle (OV) 103. Gallagher performed the OMS pod nitric acid oxidizer leak repair operation using the two newly cut access ports in the Orbiter's aft bulkhead.

  6. Overview and FY 1981 progress on open-cycle OTEC power systems

    NASA Astrophysics Data System (ADS)

    Penney, T.; Shelpuk, B.

    1981-08-01

    Progress in an advanced research and development program studying viable alternatives to closed cycle OTEC is reported. Work on a 100 MWe steam turbine, heat exchangers, and deaeration for Claude or open cycle OTEC systems are reported. Capsule descriptions of ocean energy conversion techniques are given, including wave energy conversion, ocean current energy conversion, and salinity gradient energy conversion as well as varieties of ocean thermal energy conversion.

  7. Isolation and characterization of a β-propeller gene containing phosphobacterium Bacillus subtilis strain KPS-11 for growth promotion of potato (Solanum tuberosum L.)

    PubMed Central

    Hanif, Muhammad Kashif; Hameed, Sohail; Imran, Asma; Naqqash, Tahir; Shahid, Muhammad; Van Elsas, Jan D.

    2015-01-01

    Phosphate-solubilizing and phytate-mineralizing bacteria collectively termed as phosphobacteria provide a sustainable approach for managing P-deficiency in agricultural soils by supplying inexpensive phosphate to plants. A phosphobacterium Bacillus subtilis strain KPS-11 (Genbank accession no. KP006655) was isolated from potato (Solanum tuberosum L.) rhizosphere and characterized for potato plant growth promoting potential. The strain utilized both Ca-phosphate and Na-phytate in vitro and produced 6.48 μg mL-1 indole-3-acetic acid in tryptophan supplemented medium. P-solubilization after 240 h was 66.4 μg mL-1 alongwith the production of 19.3 μg mL-1 gluconic acid and 5.3 μg mL-1 malic acid. The extracellular phytase activity was higher (4.3 × 10-10 kat mg-1 protein) than the cell-associated phytase activity (1.6 × 10-10 kat mg-1 protein). B. subtilis strain KPS-11 utilized 40 carbon sources and showed resistance against 20 chemicals in GENIII micro-plate system demonstrating its metabolic potential. Phytase-encoding gene β-propeller (BPP) showed 92% amino acid similarity to BPP from B. subtilis (accession no.WP_014114128.1) and 83% structural similarity to BPP from B. subtilis (accession no 3AMR_A). Potato inoculation with B. subtilis strain KPS-11 increased the root/shoot length and root/shoot weight of potato as compared to non-inoculated control plants. Moreover, rifampicin-resistant derivative of KPS-11 were able to survive in the rhizosphere and on the roots of potato up to 60 days showing its colonization potential. The study indicates that B. subtilis strain KPS-11 can be a potential candidate for development of potato inoculum in P-deficient soils. PMID:26106383

  8. Isolation and characterization of a β-propeller gene containing phosphobacterium Bacillus subtilis strain KPS-11 for growth promotion of potato (Solanum tuberosum L.).

    PubMed

    Hanif, Muhammad Kashif; Hameed, Sohail; Imran, Asma; Naqqash, Tahir; Shahid, Muhammad; Van Elsas, Jan D

    2015-01-01

    Phosphate-solubilizing and phytate-mineralizing bacteria collectively termed as phosphobacteria provide a sustainable approach for managing P-deficiency in agricultural soils by supplying inexpensive phosphate to plants. A phosphobacterium Bacillus subtilis strain KPS-11 (Genbank accession no. KP006655) was isolated from potato (Solanum tuberosum L.) rhizosphere and characterized for potato plant growth promoting potential. The strain utilized both Ca-phosphate and Na-phytate in vitro and produced 6.48 μg mL(-1) indole-3-acetic acid in tryptophan supplemented medium. P-solubilization after 240 h was 66.4 μg mL(-1) alongwith the production of 19.3 μg mL(-1) gluconic acid and 5.3 μg mL(-1) malic acid. The extracellular phytase activity was higher (4.3 × 10(-10) kat mg(-1) protein) than the cell-associated phytase activity (1.6 × 10(-10) kat mg(-1) protein). B. subtilis strain KPS-11 utilized 40 carbon sources and showed resistance against 20 chemicals in GENIII micro-plate system demonstrating its metabolic potential. Phytase-encoding gene β-propeller (BPP) showed 92% amino acid similarity to BPP from B. subtilis (accession no.WP_014114128.1) and 83% structural similarity to BPP from B. subtilis (accession no 3AMR_A). Potato inoculation with B. subtilis strain KPS-11 increased the root/shoot length and root/shoot weight of potato as compared to non-inoculated control plants. Moreover, rifampicin-resistant derivative of KPS-11 were able to survive in the rhizosphere and on the roots of potato up to 60 days showing its colonization potential. The study indicates that B. subtilis strain KPS-11 can be a potential candidate for development of potato inoculum in P-deficient soils. PMID:26106383

  9. Seasonal variability of inflow and outflow regimes in the Gulf of Naples

    NASA Astrophysics Data System (ADS)

    Cianelli, Daniela; Iermano, Ilaria; Mozzillo, Pasquale; Uttieri, Marco; Zambianchi, Enrico; Buonocore, Berardino; Falco, Pierpaolo; De Luca, Luigi; Giordano, Alberto; Zambardino, Giovanni

    2013-04-01

    Since 2004 the Department of Environmental Sciences of the Parthenope University manages, on behalf of AMRA (the former Competence Center for the Analysis of Environmental Risks of the Campania Region), an HF radar system composed of three transceiving stations located along the Gulf's coasts, which provide hourly data of surface currents over the whole Gulf area with 1 km of resolution. The radar system is part of a meteo-marine monitoring network; recently, in the framework of the EU-funded MED TOSCA (Tracking Oil Spills and Coastal Awareness Network) project, a modeling component was added to the network, based on the ROMS (Regional Ocean Modeling System) code. A one year-long HF radar time series and ROMS outputs of surface currents are utilized to look into the seasonal variability of current patterns in the Gulf of Naples. In particular, we focus on the net water inflow and outflow, i.e. on the exchange between the interior of the Gulf and the neighbouring Tyrrhenian Sea. This is done by computing the average surface current on a transect between the islands of Capri in the South and of Nisida in the North, which is considered as the boundary between the inner gulf and the open sea. First, a comparison between wind and HF radar data shows the crucial importance of the surface forcing on the upper circulation, dominated by breeze in late spring and summer and by more stable, offshore-oriented winds in fall and winter. Then, the analysis of the zonal component of currents allows to assess the existence of two different in-/outflow regimes associated with the above wind seasons: spring and summer show a tendency to stagnation inside the Gulf, whereas winter is characterized by a very effective water renewal mechanism. Results of ROMS simulations show a good agreement with such patterns.

  10. Cascade Models of Turbulence and Mixing

    NASA Astrophysics Data System (ADS)

    Kadanoff, Leo P.

    1997-01-01

    This note describes two kinds of work on turbulence. First it describes a simplified model of turbulent energy-cascades called the GOY model. Second it mentions work on a model of mixing in fluids. In addition to a brief historical discussion, I include some mention of our own work carried on at the University of Chicago by Jane Wang, Detlef Lohse, Roberto Benzi, Norbert Schörghofer, Scott Wunsch, Tong Zhou and myself. Our own studies are in large measure the outgrowth of a paper by M. H. Jensen, G. Paladin, and A. Vulpiani [1]. I mention this connection with some sadness because I recall Paladin's recent death in a mountain accident.

  11. Felt stigma and obesity: introducing the generalized other.

    PubMed

    Barlösius, Eva; Philipps, Axel

    2015-04-01

    People with a big body are tainted in western societies. Although most research on obesity occurs in the medical context, few studies investigate characteristics and effects of feelings and fears related to the fat stigma in the absence of overt discrimination. By linking Norbert Elias's and George H. Mead's theoretical frameworks, this paper offers a different approach to understanding and investigating felt stigma. The study is based on secondary data (25 semistructured interviews with children and adolescents). It explores internalized societal perspectives on overweight and obesity and inquires into the way in which interviewees handle the blame frame of personal responsibility during their interview. The preliminary findings suggest that specific forms of managing one's self-presentation in interviews indicate felt stigma. Consequently, the paper argues for an analytical approach that extends the focus on the content of interviews to include its dynamics. PMID:25658623

  12. Remembering antibodies coming of age.

    PubMed

    Melchers, Fritz

    2016-01-01

    Fifty years ago, Norbert Hilschmann discovered that antibodies have variable immunoglobulin domains to bind antigens, and constant domains to carry out effector functions in the immune system. Just as this happened, the author of this perspective entered the field of immunology. Ten years later, the genetic basis of antibody variability was discovered by Susumu Tonegawa and his colleagues at the Basel Institute for Immunology, where the author had become a scientific member. At the same time, Georges Köhler, a former graduate student of the author's at the Basel Institute, invented with Cesar Milstein at the Laboratory of Molecular Biology in Cambridge, England, the method to produce monoclonal antibodies. The author describes here his memories connected to these three monumental, paradigm-changing discoveries, which he observed in close proximity. PMID:27144253

  13. [Project HOPE contribution to the setting up of the professional identity of the first nurses from Alagoas, 1973-1977].

    PubMed

    Costa, Laís de Miranda Crispim; dos Santos, Regina Maria; Santos, Tânia Cristina Franco; Trezza, Maria Cristina Soares Figueiredo; Leite, Josete Luzia

    2014-01-01

    Social-historical study conducted to examine the contribution of the American Nurses of Project HOPE to the configuration of the professional identity of the first trained nurses in Alagoas, in the period of 1973-1977. The theoretical framework was the "Civilizing Process" of Norbert Elias. Primary sources were official documents and personal files of 13 respondents by oral history; the secondary sources were authors of the History of Brazil/Alagoas. Data analysis showed that the configuration of the professional identity of the first trained nurses in Alagoas was a civilizing process, with all the nuances that make up the power relations. There was a significant contribution of American Nursing. However the movement of resistance to this domination was very strong, resulting in a Course that could take advantage of technological advancement and prestige brought by the United States, to build a unique Nursing from the social fabric embroidery at this meeting with so many different cultures. PMID:25271576

  14. Kybernetische probleme in der raumfahrt

    NASA Astrophysics Data System (ADS)

    Hirzinger, G.

    The paper tries to summarize actual cybernetical problems by hand of published literature especially from NASA. After a definition given by Norbert Wiener 1960, "cybernetics is the science of control and information, no matter whether it deals with human beings or machines". In the following a special aspect is illuminated which completely stays within this definition, i.e. in how the function of man can be replaced partly or fully by machines, or in other words the question of automation. As completeness is not achievable anyhow, the remarks here concentrate on the use of robotics in space as well as on questions of navigation; two areas, which are well suited for the representation of automation topics. It is intended here to show up the state of the art in this field, to prove the necessity for more automation in space, and to make some comments on the historical development.

  15. Philosophical Approaches towards Sciences of Life in Early Cybernetics

    NASA Astrophysics Data System (ADS)

    Montagnini, Leone

    2008-07-01

    The article focuses on the different conceptual and philosophical approaches towards the sciences of life operating in the backstage of Early Cybernetics. After a short reconstruction of the main steps characterizing the origins of Cybernetics, from 1940 until 1948, the paper examines the complementary conceptual views between Norbert Wiener and John von Neumann, as a "fuzzy thinking" versus a "logical thinking", and the marked difference between the "methodological individualism" shared by both of them versus the "methodological collectivism" of most of the numerous scientists of life and society attending the Macy Conferences on Cybernetics. The main thesis sustained here is that these different approaches, quite invisible to the participants, were different, maybe even opposite, but they could provoke clashes, as well as cooperate in a synergic way.

  16. Novel procedure for characterizing nonlinear systems with memory and combating the curse of dimensionality

    NASA Astrophysics Data System (ADS)

    Nuttall, A. H.; Katz, R. A.; Hughes, D. R.; Koch, R. M.

    2015-10-01

    A well-known mathematical model for characterizing nonlinear systems was originally proposed by Vito Volterra (1860-1940) and later developed by Norbert Wiener (1894-1964). More recently, Albert Nuttall, working with coauthors, has made substantial improvements to Wiener's approach, in which kernel estimates are modeled directly rather than computed from Wiener functionals. Other enhancements made include kernel estimation using a least-square approach for obtaining a best fit to the measured system response, and procedural methods to obtain uncorrelated column-wise basis vectors in the design matrix. These techniques, among others, include: maximally-sparse sampling of the kernels (for first-, second- and third-order), combatting ill-conditioning on its own terms, and realizing an exponential decrease of the growth of the number of kernel coefficients.

  17. Control of defect localization in crystalline wrinkling by curvature and topology

    NASA Astrophysics Data System (ADS)

    Lopez Jimenez, Francisco

    We investigate the influence of curvature and topology on crystalline wrinkling patterns in generic elastic bilayers. Our numerical analysis predicts that the total number of defects created by adiabatic compression exhibits universal quadratic scaling for spherical, ellipsoidal and toroidal surfaces over a wide range of system sizes. However, both the localization of individual defects and the orientation of defect chains depend strongly on the local Gaussian curvature and its gradients across a surface. Our results imply that curvature and topology can be utilized to pattern defects in elastic materials, thus promising improved control over hierarchical bending, buckling or folding processes. Generally, this study suggests that bilayer systems provide an inexpensive yet valuable experimental test-bed for exploring the effects of geometrically induced forces on assemblies of topological charges. Joint work with Norbert Stoop, Romain Lagrange, Jorn Dunkel and Pedro M. Reis.

  18. Physics in the Art Museum

    NASA Astrophysics Data System (ADS)

    Dale, Daniel A.; Bailey, Brenae L.

    2003-02-01

    Parisian artist Paul Signac met the impressionists Claude Monet and Georges Seurat in 1884. Their influence spurred his work in pointillism (or, where the juxtaposition of small dots of color in conjunction with the limited resolving power of the human eye lead to the impression of color coalescence).1-4 To stimulate a cross-disciplinary appreciation of science and art, we used the University of Wyoming Art Museum's Signac painting "Barques de Pêche à Marseilles" (see Fig. 1) to explore diffraction theory and the anatomical limitations to our vision during an optics exercise done in the museum.

  19. STS-46 crewmembers handle water hoses during fire training at JSC's Fire Pit

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, crewmembers, directing the spray of two water hoses, approach a blaze in JSC's Fire Training Pit located across from the Gilruth Center Bldg 207. Manning the hose in the foreground are Commander Loren J. Shriver (left) and Italian Payload Specialist Franco Malerba. Holding a second hose are European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier and MS Franklin R. Chang-Diaz who is aiming nozzle at the fire. Between the water hoses is a fire fighting training instructor. In the distance JSC's water tower and building facilities can be seen.

  20. Taking a geometric look at the socio-political functioning schemes of the living. Catastrophe theory and theoretical sociology.

    PubMed

    Morier, Clément

    2013-09-01

    The aim of this communication is to consider morphological processes in sociology, mainly through the study of the stability of forms of sociality. At the same time, it aims to study the regulation of constraints, related to an increasingly conflictual environment, through political organization. We use a specific theoretical framework: the catastrophe theory developed by René Thom in topology, further developed by Claude Bruter from a physics point of view, and reworked by Jacques Viret in biology. The idea is to show the existence of archetypal processes organizing social forms. PMID:23943093

  1. STS-46 Onboard Photo:Scientist Supports the TOP Activities on Flight Deck

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This Space Shuttle Orbiter Atlantis (STS-46) onboard photo shows Swiss scientist Claude Nicollier of the European Space Agency (ESA) supporting the Tether Opitical Phenomena (TOP) activities on the flight deck. The Tethered Satellite System (TSS) was a cooperative development effort by the Italian Space Agency (ASI) and NASA made capable of deploying and retrieving a satellite which is attached by a wire tether from distances up to 100 km from the Orbiter. These free-flying satellites are used as observation platforms outside of the Orbiter.

  2. The Space Shuttle Columbia clears the tower to begin the mission. The liftoff occurred on schedule

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 LAUNCH VIEW --- The Space Shuttle Columbia clears the tower to begin the mission. The liftoff occurred on schedule at 3:18:00 p.m. (EST), February 22, 1996. Visible at left is the White Room on the orbiter access arm through which the flight crew had entered the orbiter. Onboard Columbia for the scheduled two-week mission were astronauts Andrew M. Allen, commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and astronauts Maurizio Cheli, Jeffrey A. Hoffman and Claude Nicollier, along with payload specialist Umberto Guidioni. Cheli and Nicollier represent the European Space Agency (ESA), while Guidioni represents the Italian Space Agency (ASI).

  3. A remote camera at Launch Pad 39B, at the Kennedy Space Center (KSC), recorded this profile view of

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 LAUNCH VIEW --- A remote camera at Launch Pad 39B, at the Kennedy Space Center (KSC), recorded this profile view of the Space Shuttle Columbia as it cleared the tower to begin the mission. The liftoff occurred on schedule at 3:18:00 p.m. (EST), February 22, 1996. Onboard Columbia for the scheduled two-week mission were astronauts Andrew M. Allen, commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and astronauts Maurizio Cheli, Jeffrey A. Hoffman and Claude Nicollier, along with payload specialist Umberto Guidioni. Cheli and Nicollier represent the European Space Agency (ESA), while Guidioni represents the Italian Space Agency (ASI).

  4. The dawn of open heart surgery: an overview of the symposium that celebrated the 50th anniversary of controlled cross circulation.

    PubMed

    DeWall, Richard

    2005-01-01

    At the 50th Anniversary of Open Heart Surgery symposium sponsored by the Lillehei Heart Institute of the University of Minnesota in October 2004, the following pioneers in open heart surgery development presented papers of historical interest: Drs. Peter Agre, Robert W. Anderson, William Baumgartner, Alain Carpentier, Aldo Casteneda, Randolph Chitwood, Jr., Denton Cooley, Fred Crawford, Michael DeBakey, Richard DeWall, Vincent Gott, Claude Lenfant, Floyd Loop, James Holler, Glen Nelson, Norman Shumway, Manny Villafana, Richard Weisel, and Sir Magdi Yacoub. PMID:16106145

  5. STS-46 ESA MS Nicollier conducts IFM on OV-104's waste collection system

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier, wearing goggles, face mask, and rubber gloves, reviews inflight maintenance (IFM) checklist procedures before starting waste collection system (WCS) fan separator repair. One of two fan separators used to transfer waster water from the waste management compartment (WMC) to the waste water tank has failed. The suspected accumulation of water in the separator was believed to have occurred during a test dumping of waste water at a lower than normal pressure to evaluate the performance of new nozzles. The WMC is located on the middeck of Atlantis, Orbiter Vehicle (OV) 104.

  6. STS-46 crew, wearing LESs, prepares for deorbit on OV-104's flight deck

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 crewmembers, wearing launch and entry suits (LESs) and launch and entry helmets (LEHs), are seated on the flight deck of Atlantis, Orbiter Vehicle (OV) 104. They review checklist procedures as they prepare for deorbit sequence and landing. At the far left, at the pilots station is Pilot Andrew M. Allen. Behind Allen is European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier in a mission specialists seat on the aft flight deck. Next to Nicollier is MS Marsha S. Ivins. Just out of the frame at left is Commander Loren J. Shriver who guided OV-104 in for its Florida landing.

  7. F.S.V.B. Volleyball

    ScienceCinema

    None

    2011-04-25

    22me assemblée des délégués de la Fédération Suisse de Volley Ball (F.S.V.B.), en présence entre autres de Claude Delay, représentant de la société fédérale de gymnastique et Hans Gauer, représentant de l'association suisse de gymnastique féminine. Annonce d'une démonstration d'un mini match de volley ball à Meyrin dans l'après-midi.

  8. STS-103 Crew Activity Report/Flight Day 1 Highlights

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Live footage of the astronauts sitting around the table with the traditional cake is presented. The crew of Discovery, Mission Commander Curtis L. Brown, Pilot Scott J. Kelly, Mission Specialists Steven L. Smith, C. Michael Foale, John M. Grunsfeld, Claude Nicollier, and Jean-Francois Clervoy are seen executing various activities including suit-up, walkout to the Astro-Van, and strap-in into the shuttle. Also presented are beautiful panoramic views of the shuttle on the pad. During this night launch, footage of the main engine start, ignition of the boosters, liftoff of Discovery, and separation of the solid rocket boosters are seen.

  9. STS-46 ESA MS Nicollier and PLC Hoffman pose on OV-104's aft flight deck

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier (left) and MS and Payload Commander (PLC) Jeffrey A. Hoffman pose in front of the onorbit station controls on the aft flight deck of Atlantis, Orbiter Vehicle (OV) 104. The overhead windows W7 and W8 appear above their heads and the aft flight deck viewing windows W9 and W10 behind them. Hoffman and Nicollier have been training together for a dozen years at JSC. Hoffman was an astronaut candidate in 1978 and Nicollier accompanied a group of trainees in 1980. Note the partially devoured chocolate Space Shuttle floating near the two.

  10. Payload specialist Umberto Guidioni, wearing the partial pressure launch and entry garment, prepares

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 ONBOARD VIEW --- Payload specialist Umberto Guidioni, wearing the partial pressure launch and entry garment, prepares for the de-orbit phase of the 16-day flight. Guidioni represents the Italian Space Agency (ASI). The seven member crew was launched aboard the Space Shuttle Columbia on February 22, 1996, and landed on March 9, 1996. Crew members were Andrew M. Allen, mission commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and Maurizio Cheli, European Space Agency (ESA); Jeffrey A. Hoffman and Claude Nicollier, (ESA), all mission specialists; along with Guidioni.

  11. F.S.V.B. Volleyball

    SciTech Connect

    2006-06-07

    22me assemblée des délégués de la Fédération Suisse de Volley Ball (F.S.V.B.), en présence entre autres de Claude Delay, représentant de la société fédérale de gymnastique et Hans Gauer, représentant de l'association suisse de gymnastique féminine. Annonce d'une démonstration d'un mini match de volley ball à Meyrin dans l'après-midi.

  12. STS-46 MS Nicollier and Payload Specialist Malerba during JSC egress training

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier (left) and Italian Payload Specialist Franco Malerba, wearing launch and entry suits (LESs) and launch and entry helmets (LEHs), pose on the poolside of JSC's Weightless Environment Training Facility (WETF) Bldg 29. The two crewmembers are preparing for a launch emergency egress (bailout) simulation during which they will be dropped into the WETF pool. After landing in the water they will test crew escape system (CES) equipment and flotation devices.

  13. Understanding computers or some of the things you always wanted to know about computers ... but were afraid to ask.

    PubMed

    Duffy, P; McLendon, K

    1991-08-01

    Criteria for computer systems evaluation are changing. No longer can we rely on an evaluation based solely on what the combination of hardware and software does for the user (functional criteria). Significant improvements in software productivity have occurred in recent years as a result of the availability of tools such as relational database management systems and fourth-generation languages. Meanwhile new technologies such as image processing and graphical user interfaces, e.g. MS-Windows and X Window, are coming onstream. Most of these technologies and capabilities require substantially more computing resources than traditional character-based systems. Fortunately, the open systems revolution is creating a more competitive marketplace and computer price/performance ratios are soaring, making the additional computing resources readily available at reasonable prices. But the opportunities of the future will not be for everyone. They will exist only for those medical record practitioners who recognize that a shift away from purely functional evaluation is necessary. Those that make the shift successfully will not become computer technicians, but they will understand the few technical criteria that are truly essential in systems evaluation. They will, in short, apply the 80/20 principle successfully to make future system selections. Medical record professionals must take steps to upgrade their computer system knowledge in order to accommodate the needs of technical criteria evaluation. For the active practitioner this means taking the time to learn from the many sources available in print, educational programs, and knowledgeable persons. Students should seek out courses that will give them a balanced view of the computer sciences, without being overloaded with specifics. AMRA should look for ways to augment the computer sciences requirements in the student's curriculum. Development of study tracks that concentrate on combining standard curricula with computer

  14. Physiological regulation through learnt control of appetites by contingencies among signals from external and internal environments.

    PubMed

    Booth, David A

    2008-11-01

    As reviewed by [Cooper, S. J. (2008). From Claude Bernard to Walter Cannon: emergence of the concept of homeostasis. Appetite 51, 419-27.] Claude Bernard's idea of stabilisation of bodily states, as realised in Walter B. Cannon's conception of homeostasis, took mathematical form during the 1940s in the principle that externally originating disturbance of a physiological parameter can feed an informative signal around the brain to trigger counteractive processes--a corrective mechanism known as negative feedback, in practice reliant on feedforward. Three decades later, enough was known of the physiology and psychology of eating and drinking for calculations to show how experimentally demonstrated mechanisms of feedforward that had been learnt from negative feedback combine to regulate exchanges of water and energy between the body and the surroundings. Subsequent systemic physiology, molecular neuroscience and experimental psychology, however, have been traduced by a misconception that learnt controls of intake are 'non-homeostatic', the myth of biological 'set points' and an historic failure to address evidence for the ingestion-adapting information-processing mechanisms on which an operationally integrative theory of eating and drinking relies. PMID:18640162

  15. New Revolutionary Possibilities in Geodesy Providing the Discoveries Awarded for Physics in 2005 and 1997

    NASA Astrophysics Data System (ADS)

    Solaric, N.; Solaric, M.; Svehla, D.

    2012-03-01

    Nobel Prize for Physics in the year 2005 was awarded to Roy J. Glauber, John L. Hall and Theodor W. Hänsch in recognition of their contribution in the field of optics. Nobel Prize for physics in 1997 was awarded to Steven Chu, Claude Cohen-Tannoudji and William D. Phillips for the discovery and development of the method by means of which the atoms are cooled down and trapped by laser light. The improvements that were suggested by Theodor W. Hänsch and John L. Hall supported by the discoveries made by Steven Chu, Claude Cohen-Tannoudji and William Phillips offer new revolutionary possibilities for significant improvement of measuring accuracy in geodesy and also in many other fields of science and application. By means of optical clocks it will be possible to measure time even more precisely than by atomic clocks, providing thus more precise determination of navigational satellite orbits, and consequently the positions of points on the Earth's surface. It also opens the possibility of determining the difference of gravitational potential between the points on the Earth's surface applying thereby the theory of relativity by Einstein. In this way it will be possible to connect the heights between the continents by means of direct measurements, and also to improve the connection of levelling networks between individual countries on the continents. More precise distance measurements will also bi provided.

  16. Direct Measurements of Electrical Transport Through Single DNA Molecules of Complex Sequence

    NASA Astrophysics Data System (ADS)

    Cohen, Hezy; Nogues, Claude

    2005-03-01

    Seemingly contradicting results raised a debate over the ability of DNA to transport charge and the nature of the conduction mechanisms through it. We developed an experimental approach for measuring current through DNA molecules, chemically connected on opposite ends to a metal substrate and to a gold nanoparticle, using a conductive atomic force microscope.^1 Many samples could be made due to the experimental approach adopted here that enabled obtaining reproducible results in various samples, conditions and measurement methods. We present multileveled evidence for charge transport through 26 base-pairs long dsDNA of a complex sequence, characterized by S-shaped I-V curves that show currents higher than 220 nA at 2 V.^2 This significant observation implies that a coherent or band transport mechanism takes over for the high currents (> 1 nA). 1. Claude Nogues, Sidney R. Cohen, Shirley S. Daube, and Ron Naaman, ``Electrical properties of short DNA oligomers characterized by conducting atomic force microscopy,'' PCCP, 2004, 18. 2. Hezy Cohen, Claude Nogues Ron Naaman and Danny Porath. ``Direct Measurement of Electrical Transport Through Single DNA Molecules,'' submitted.

  17. Operational experience of the OC-OTEC experiments at NELH

    SciTech Connect

    Link, H

    1989-02-01

    The Solar Energy Research Institute, under funding and program direction from the US Department of Energy, has been operating a small-scale test apparatus to investigate key components of open- cycle ocean thermal energy conversion (OC-OTEC). The apparatus started operations in October 1987 and continues to provide valuable information on heat-and mass-transfer processes in evaporators and condensers, gas sorption processes as seawater is depressurized and repressurized, and control and instrumentation characteristics of open-cycle systems. Although other test facilities have been used to study some of these interactions, this is the largest apparatus of its kind to use seawater since Georges Claude`s efforts in 1926. The information obtained from experiments conducted in this apparatus is being used to design a larger scale experiment in which a positive net power production is expected to be demonstrated for the first time with OC-OTEC. This paper describes the apparatus, the major tests conducted during its first 18 months of operation, and the experience gained in OC-OTEC system operation. 13 refs., 8 figs.

  18. [Genealogical study of the Pijart dynasty, goldsmiths or apothecaries in Paris in the 16th and 17th centuries].

    PubMed

    Warolin, Christian

    2007-10-01

    The Pijart dynasty, established in Paris during the 16th and 17th centuries, included apothecaries and goldsmiths who had a common ancestor, Michel Pijart, warden of the goldsmith's guild (garde de l'orfèvrerie) in 1507. He was married to Jehanne Daumont and died 23rd July 1524. This couple had four sons, all goldsmiths, Pierre, Michel, Jehan and Nicolas. Pierre married twice. His first wife, Philippe Dusseau, was the sister of a famous apothecary. Only their eldest son, François, chose the profession of apothecary; the other three, Jacques, Jehan and Philibert, all followed their father's profession. By his second marriage to Marie de Mézières, Pierre had two sons, Claude the elder and Claude the younger, who both became goldsmiths. Thus, the goldsmith's trade became the favoured profession of the Pijart family. Professional endogamy prevailed in this dynasty, after the fashion of merchants belonging to the six most prestigious guilds (Six-Corps de métiers). Goldsmiths and apothecaries retained strong family ties, demonstrated by family reunions (baptisms, betrothals, etc.). It is undisputable that the renown of this dynasty is based on the fame of its goldsmiths. However, through marriage, the Pijart's developed links with other families of apothecaries, of which the most outstanding were the Boulduc's. PMID:18348497

  19. STS-103 Flight Day 5 Highlights and Crew Activities Report

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Highlights of the fifth day of the STS-103 mission on board the space shuttle Discovery are shown in this videotape. The mission was led by Commander Curtis L. Brown, with Pilot Scott J Kelly, and Mission Specialists Steven L. Smith, Jean-Francois Clervoy, John M. Grunsfeld, Michael Foale, and Claude Nicollier. The main purpose of the mission was to service the Hubble Space Telescope (HST). The primary objective of the mission was to replace all six of the gyroscopes that make up the three Rate Sensor Units. In addition the Astronauts installed a new computer. During the 5th day Michael Foale and Claude Nicollier performed the servicing of the HST in an 8 hour 10 minute Extravehicular Activity (EVA). The servicing included the removal of the old computer and the installation of a new, faster computer with more memory. They also installed a new outer thermal layer to protect the computer. After this was finished the astronauts replaced one of the Fine Guidance Sensors (FGS), an optical sensor which allows NASA to point the telescope in the desired direction. The video includes actual live views of the HST in the shuttle's service bay, and footage of the repair and servicing EVA.

  20. Review of the recording and age of the Mono Lake Excursion

    NASA Astrophysics Data System (ADS)

    Coe, R.; Liddicoat, J.

    2009-04-01

    Among the brief departures from gradual, long-term behaviour of the palaeomagnetic field in the Brunhes Normal Chron that reached opposite polarity or have a Virtual Geomagnetic Pole deep in the southern hemisphere, the first to be reported is the Laschamp Excursion (LE) in volcanic rocks in the Massif Central in France (Bonhommet and Zahringer, 1969). They originally believed it occurred between about 9,000 to 20,000 years before present, but it is now assigned an age of about 40,000 years B.P. (Guillou et al., 2004). Denham and Cox (1971) unsuccessfully sought the LE in exposed lake sediments that seemed to span that interval in the Mono Basin in the western Great Basin of the U.S., but instead encountered anomalous field behaviour that is called the Mono Lake Excursion (MLE)(Liddicoat and Coe, 1979). As a tribute to Norbert Bonhommet, who assisted us in our initial field work in the Mono Basin and shared a long-standing interest in the LE and MLE, we will review the palaeomagnetic behaviour and age of the MLE in the Mono Basin and elsewhere, for which there are nearly 20 reports of its occurrence globally, and evaluate the recent suggestion that the excursion at Mono Lake and the LE are the same.

  1. Gregory Bateson and the mathematicians: from interdisciplinary interaction to societal functions.

    PubMed

    Heims, S P

    1977-04-01

    An instance of fruitful cross-disciplinary contacts is examined in detail. The ideas involved include (1) the double-blind hypothesis for schizophrenia, (2) the critique of game theory from the viewpoint of anthropology and psychiatry, and (3) the application of concepts of communication theory and theory of logical types to an interpretation of psychoanalytic practice. The protagonists of the interchange are Gregory Bateson and the two mathematicians Norbert Wiener and John von Neumann; the date, March 1946. This interchange and its sequels are described. While the interchanges between Bateson and Wiener were fruitful, those between Bateson and von Neumann were much less so. The latter two held conflicting premises concerning what is significant in science; Bateson's and Wiener's were compatible. In 1946, Wiener suggested that information and communication might be appropriate central concepts for psychoanalytic theory--a vague general idea which Bateson (with Ruesch) related to contemporary clinical practice. For Bateson, Wiener, and von Neumann, the cross-disciplinary interactions foreshadowed a shift in activities and new roles in society, to which the post World War II period was conducive. Von Neumann became a high-level government advisor; Wiener, an interpreter of science and technology for the general public; and Bateson a counter-culture figure. PMID:325068

  2. Quantum Error Correction: Optimal, Robust, or Adaptive? Or, Where is The Quantum Flyball Governor?

    NASA Astrophysics Data System (ADS)

    Kosut, Robert; Grace, Matthew

    2012-02-01

    In The Human Use of Human Beings: Cybernetics and Society (1950), Norbert Wiener introduces feedback control in this way: ``This control of a machine on the basis of its actual performance rather than its expected performance is known as feedback ... It is the function of control ... to produce a temporary and local reversal of the normal direction of entropy.'' The classic classroom example of feedback control is the all-mechanical flyball governor used by James Watt in the 18th century to regulate the speed of rotating steam engines. What is it that is so compelling about this apparatus? First, it is easy to understand how it regulates the speed of a rotating steam engine. Secondly, and perhaps more importantly, it is a part of the device itself. A naive observer would not distinguish this mechanical piece from all the rest. So it is natural to ask, where is the all-quantum device which is self regulating, ie, the Quantum Flyball Governor? Is the goal of quantum error correction (QEC) to design such a device? Devloping the computational and mathematical tools to design this device is the topic of this talk.

  3. British Muslims and the UK government's 'war on terror' within: evidence of a clash of civilizations or emergent de-civilizing processes?

    PubMed

    Vertigans, Stephen

    2010-03-01

    In the immediate aftermath of the September 2001 attacks on America, defending civilization was quickly established at the core of the 'war on terror'. Unintentionally or otherwise this incorporation of civilization connected with Samuel Huntington's 'Clash of Civilizations' thesis. Within the 'war on terror' the dark side of counterterrorism has become apparent through international practices like extrajudicial killing, extraordinary rendition and torture. The impact of Western governments' policies upon their indigenous Muslim populations has also been problematic but social and political analysis has been relatively limited. This paper seeks to help address the scarcity of sociological contributions. Hidden costs of the UK government's attempts to utilize violence and enhance social constraints within the nation-state are identified. It is argued that although counterterrorism strategies are contributing to a self-fulfilling spiral of hatred that could be considered evidence in support of the 'Clash of Civilizations', the thesis is unhelpful when trying to grasp the underlying processes. Instead the paper draws upon Norbert Elias's application of the concepts of 'civilizing' and 'de-civilizing' to help improve levels of understanding about the processes and consequences of particular Muslim communities being targeted by security forces. The paper concludes with an exploration of the majority of the population's acquiescence and willingness to accept restraints upon Muslims in order to safeguard their own security. PMID:20377595

  4. Nurses' daily life: gender relations from the time spent in hospital1

    PubMed Central

    Pereira, Audrey Vidal

    2015-01-01

    Objective: to analyze the everyday life of nurses through the sexual work division as well as through interdependence relations and the time in hospital. Method: quanti-qualitative study, based on the Time Use Survey and in Norbert Elias's Configuration Theory of Interdependencies. Daily shifts distribution record, directed by 42 participants - with self-confrontation - by interviews which drew dialogues on subjective aspects of the everyday experiences related to use of time, based on a job at a university hospital. The theoretical intake that founded data analysis was based on concepts of conflicts of interest, power struggles, sexual work division and polychronic-monochronic concepts - whether the work environment demands multitasking nurses or not. Results: time records allowed to observe differences between the groups studied, useful to identify conflicts, tensions, power struggles and gender inequalities in interviewees' everyday affairs that do not only affect physical and mental health, but also their way of life. Conclusion: the analytical path pointed out the need for public policies that promote equity in gender relations, keeping at sight the exercise of plural discourses and tolerant stances capable to respect differences between individual and collective time. PMID:26487146

  5. Zeit im Wandel der Zeit.

    NASA Astrophysics Data System (ADS)

    Aichelburg, P. C.

    Contents: Einleitung(P. C. Aichelburg). 1. Über Zeit, Bewegung und Veränderung (Aristoteles). 2. Ewigkeit und Zeit (Plotin). 3. Was ist die Zeit? (Augustinus). 4. Von der Zeit (Immanuel Kant). 5. Newtons Ansichten über Zeit, Raum und Bewegung (Ernst Mach). 6. Über die mechanische Erklärung irreversibler Vorgänge (Ludwig Boltzmann). 7. Das Maß der Zeit (Henri Poincaré). 8. Dauer und Intuition (Henri Bergson). 9. Die Geschichte des Unendlichkeitsproblems (Bertrand Russell). 10. Raum und Zeit (Hermann Minkowski). 11. Der Unterschied von Zeit und Raum (Hans Reichenbach). 12. Newtonscher und Bergsonscher Zeitbegriff (Norbert Wiener). 13. Die Bildung des Zeitbegriffs beim Kinde (JeanPiaget).14. Eine Bemerkung über die Beziehungen zwischen Relativitätstheorie und der idealistischen Philosophie (Kurt Gödel). 15. Der zweite Hauptsatz und der Unterschied von Vergangenheit und Zukunft (Carl Friedrich v. Weizsäcker). 16. Zeit als physikalischer Begriff (Friedrich Hund). 17. Zeitmessung und Zeitbegriff in der Astronomie (Otto Heckmann). 18. Kann die Zeit rückwärts gehen? (Martin Gardner). 19. Zeit und Zeiten (Ilya Prigogine, Isabelle Stengers). 20. Zeit als dynamische Größe in der Relativitätstheorie (P. C. Aichelburg).

  6. Transcending disciplines: Scientific styles in studies of the brain in mid-twentieth century America.

    PubMed

    Abraham, Tara H

    2012-06-01

    Much scholarship in the history of cybernetics has focused on the far-reaching cultural dimensions of the movement. What has garnered less attention are efforts by cyberneticians such as Warren McCulloch and Norbert Wiener to transform scientific practice in an array of disciplines in the biomedical sciences, and the complex ways these efforts were received by members of traditional disciplines. In a quest for scientific unity that had a decidedly imperialistic flavour, cyberneticians sought to apply practices common in the exact sciences-mainly theoretical modeling-to problems in disciplines that were traditionally defined by highly empirical practices, such as neurophysiology and neuroanatomy. Their efforts were met with mixed, often critical responses. This paper attempts to make sense of such dynamics by exploring the notion of a scientific style and its usefulness in accounting for the contrasts in scientific practice in brain research and in cybernetics during the 1940s. Focusing on two key institutional contexts of brain research and the role of the Rockefeller and Macy Foundations in directing brain research and cybernetics, the paper argues that the conflicts between these fields were not simply about experiment vs. theory but turned more closely on the questions that defined each area and the language used to elaborate answers. PMID:22520204

  7. Nervous system in the fibrillar theory of Giorgio Baglivi.

    PubMed

    Zurak, N

    2000-01-01

    The drafts, epistles, headwords, and conceptual basis known as the fibrillar theory of Giorgio Baglivi, published in his book entitled De fibra motrice et morbosa, were analyzed in an attempt to re-evaluate Baglivi's contribution, generally considered quite modest, to the development of scientific thought on the nervous system functions. The analysis revealed Baglivi's identification of the reflex organization, vegetative nervous system function, and neural aspect of the vasomotor function to be surprisingly valuable. I believe that the lucidity and genuine contemporariness of Baglivi's standpoints arise the question of the historical precedence in the discovery of these functions (it is usually attributed to F.X. Bichat for vegetative nervous system, and to Claude Bernard for vasomotor nerves). In the light of these facts, the need of an expert revision of the history of discovering nervous system functions is suggested. PMID:11624709

  8. Shock at the millennium II. Walter B. Cannon and Lawrence J. Henderson.

    PubMed

    Chambers, N K; Buchman, T G

    2001-10-01

    Walter B. Cannon and Lawrence J. Henderson, students of shock in the early twentieth century, were contemporaries for four decades in the Harvard Department of Physiology. While their discoveries continue to have important clinical applications, both men established complementary methods of scientific investigation and description. Both men were inspired by Claude Bernard, hewing to his principle of the stability of the milieu intérieur. Cannon, the traditional experimentalist, employed a reductionist approach by holding constant the confounding variables of his experiments; in contrast, Henderson, the strategist of theoretical analysis, deduced patterns and relationships from less constrained models, focusing on complexity using mathematics and graphs. In delineation, Cannon described mechanisms; Henderson described the organization of systems. Cannon's emphasis on homeostasis with the identification of feedback arcs dominated shock research for the balance of the twentieth century. Henderson's perspective designating the importance of organization to those restorative mechanisms could well reemerge to dominate the twenty-first. PMID:11580110

  9. Whether weather affects music

    NASA Astrophysics Data System (ADS)

    Aplin, Karen L.; Williams, Paul D.

    2012-09-01

    The creative output of composers, writers, and artists is often influenced by their surroundings. To give a literary example, it has been claimed recently that some of the characters in Oliver Twist and A Christmas Carol were based on real-life people who lived near Charles Dickens in London [Richardson, 2012]. Of course, an important part of what we see and hear is not only the people with whom we interact but also our geophysical surroundings. Of all the geophysical phenomena to influence us, the weather is arguably the most significant because we are exposed to it directly and daily. The weather was a great source of inspiration for artists Claude Monet, John Constable, and William Turner, who are known for their scientifically accurate paintings of the skies [e.g., Baker and Thornes, 2006].

  10. The STS-103 crew address family and friends at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew address family and friends at Launch Pad 39B. From left to right are Pilot Scott J. Kelly, Commander Curtis L. Brown Jr., and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Frangois Clervoy of France , Claude Nicollier of Switzerland and Steven L. Smith. Nicollier and Clervoy are with the European Space Agency. In the background is Space Shuttle Discovery, alongside the lighted Fixed Service Structure. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. The mission is expected to last about 8 days and 21 hours. Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:25 p.m. EST.

  11. [Adélaïde Hautval (1906-1988): An exemplary medical personality].

    PubMed

    Halioua, Bruno; Hauptmann, Georges

    2015-12-01

    Adélaïde Hautval (1906-1988), psychiatrist, was arrested in April 1942 having defended a Jewish family abused by German soldiers. She was imprisoned in Bourges and in several camps in France (Pithiviers, Beaune-la-Rolande, Orléans, Romainville) before being deported as a "Friend of the Jews" at Auschwitz in the convoy of 23 January 1943, said 31,000 convoy with 229 other resistant women, Marie-Claude Vaillant-Couturier, Charlotte Delbo, Danielle Casanova. She refused to participate in the "medical" experience of Nazi doctors Clauberg, Schumann, Wirths and Mengele at Birkenau. She was then deported to Ravensbrück. During her deportation, she illustrated her dedication in the medical management of the deportees. She testified repeatedly on her experience of remote doctor. Hautval Adélaïde was the first French woman doctor named Righteous among the Nations in 1965. PMID:26411305

  12. Na(+)/H(+) antiporter (NHE1) and lactate/H(+) symporters (MCTs) in pH homeostasis and cancer metabolism.

    PubMed

    Counillon, Laurent; Bouret, Yann; Marchiq, Ibtissam; Pouysségur, Jacques

    2016-10-01

    The Na(+)/H(+)-exchanger NHE1 and the monocarboxylate transporters MCT1 and MCT4 are crucial for intracellular pH regulation, particularly under active metabolism. NHE1, a reversible antiporter, uses the energy provided by the Na(+) gradient to expel H(+) ions generated in the cytosol. The reversible H(+)/lactate(-) symporters MCT1 and 4 cotransport lactate and proton, leading to the net extrusion of lactic acid in glycolytic tumors. In the first two sections of this article we review important features and remaining questions on the structure, biochemical function and cellular roles of these transporters. We then use a fully-coupled mathematical model to simulate their relative contribution to pH regulation in response to lactate production, as it occurs in highly hypoxic and glycolytic tumor cells. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26944480

  13. STS-46 crewmembers and backup payload specialist in JSC WETF egress training

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, Pilot Andrew M. Allen, wearing launch and entry suit (LES) and launch and entry helment (LEH), is assisted by training support personnel as he prepares to simulate a parachute glide into water (the pool) during a launch emergency egress (bailout) simulation in JSC's Weightless Environment Training Facility Bldg 29. Allen holds onto the parachute straps before he is hoisted over the pool. Also in LES gear and waiting along the poolside are (left to right) backup Italian Payload Specialist Umberto Guidoni, Italian Payload Specialist Franco Malerba, and European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier. SCUBA-equipped divers in the pool are seen at the bottom of the frame listening to instructions.

  14. French work on ocean thermal energy conversion

    NASA Astrophysics Data System (ADS)

    Marchand, P.

    The ocean is discussed as a world-wide potential source of renewable energy, with special attention given to the 'deposit' of ocean thermal energy, which is determined by the temperature difference existing between surface water and that at a depth of 1000 m. A brief history of work done in France is presented, and mention is made of the work of d'Arsonval (1881), Claude and Boucherot (1926), and of projects, such as those at Abidjan and Guadeloupe. Attention is given to the French ocean thermal energy sites, to the Empain-Schneider closed-cycle studies, and the open-cycle floating ocean thermal energy station, with a discussion of thermodynamic considerations and cold water pipes. Problems and prospects are reviewed.

  15. Cavernous sinus thrombosis secondary to aspergillus granuloma: A case report and review of the literature.

    PubMed

    Brenet, Esteban; Boulagnon-Rombi, Camille; N'guyen, Yohan; Litré, Claude-Fabien

    2016-10-01

    Cavernous sinus thrombosis is a rare but serious complication of sphenoid aspergillosis. The rarity of this pathology makes its diagnostic very difficult on a clinical, biological and radiological sense. The authors present a case of cavernous sinus thrombosis with ipsilateral internal carotid artery thrombosis secondary to a non-invasive sphenoid aspergillosis in an immunocompetent host, responsible of a cavernous syndrome associated to a Claude Bernard Horner syndrome. One year after surgery, the patient is still asymptomatic without recurrence. Diagnostic modalities are detailed and several management of this pathology are compared. Surgery is essential in a diagnostic and therapeutic sense. There is no evidence of the interest of adjuvant therapies such as antibiotic and anticoagulation. Concerning the antifungal treatment, the attitude towards a non-invasive sphenoid aspergillosis in an immunocompetent host is unclear. PMID:26860234

  16. Bruner's Search for Meaning: A Conversation between Psychology and Anthropology

    PubMed Central

    Mattingly, Cheryl; Lutkehaus, Nancy C.; Throop, C. Jason

    2010-01-01

    We introduce a special issue of Ethos devoted to the work of Jerome Bruner and his careerlong attempts to seek innovative ways to foster a dialogue between psychology and anthropology. The articles in this special issue situate Bruner's meaning-centered approach to psychology and his groundbreaking work on narrative in the broader context of the developmental trajectory of both of fields of inquiry. Bruner's work has been enormously influential in the subfields of cultural psychology and psychological anthropology, especially because of his important contributions to our understanding of the intimate relationship between culture and mind. We examine Bruner's past and ongoing engagement with such luminary figures as Lev Vygotsky, Jean Piaget, Alfred Kroeber, Claude Lévi-Strauss, and Clifford Geertz to highlight points of convergence and tension between his version of cultural psychology and contemporary theorizing and practice in psychological anthropology. We also review his practical and theoretical contributions to the fields of medicine, law, and education. PMID:20706551

  17. Beautiful Surfaces. Style and Substance in Florentius Schuyl's Illustrations for Descartes' Treatise on Man.

    PubMed

    Chan, Eleanor

    2016-01-01

    The assumption that the Cartesian bête-machine is the invention of René Descartes (1596-1650) is rarely contested. Close examination of Descartes' texts proves that this is a concept founded not on the basis of his own writings, but a subsequent critical interpretation, which developed and began to dominate his work after his death. Descartes' Treatise on Man, published posthumously in two rival editions, Florentius Schuyl's Latin translation De Homine (1662), and Claude Clerselier's Traité de l'homme, has proved particularly problematic. The surviving manuscript copies of the Treatise on Man left no illustrations, leaving both editors the daunting task of producing a set of images to accompany and clarify the fragmented text. In this intriguing case, the images can be seen to have spoken louder than the text which they illustrated. This paper assesses Schuyl's choice to represent Descartes' Man in a highly stylized manner, without superimposing Clerselier's intentions onto De Homine. PMID:27356337

  18. Mendelevium: The Way It Was

    ScienceCinema

    None

    2014-10-28

    A reel of black & white film shot nearly 60 years ago has surfaced at Berkeley Lab, depicting the discovery of Mendelevium - or Element 101 - as reenacted by some of the legendary scientists who did the actual work at that time. Since the 1940s, Berkeley Lab scientists were locked in a race to synthesize new elements, and more often than not, they came out winners. Sixteen elements, most of them in the actinide series at the bottom of the periodic table, were discovered and synthesized by its researchers. Retired Berkeley Lab physicist Claude Lyneis found the reel in a box of dusty and deteriorating films slated for disposal. Using digital editing skills he acquired to make videos of his son's lacrosse team, Lyneis has produced and narrated an excerpt of this nearly-lost footage. It is an entertaining and informative look at the pioneering physics performed at UC Berkeley and Lawrence Berkeley National Laboratory's hillside campus.

  19. STS-46 Atlantis, OV-104, crew participates in fire training at JSC

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, crewmembers participate in fire fighting and fire training exercises in JSC's Fire Training Pit located across from the Gilruth Center Bldg 207. Lined up along fire hoses and spraying water at the blazing fire pit are: (front to back in the foreground) European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier, directing the hose nozzle, MS and Payload Commander (PLC) Jeffrey A. Hoffman, MS Marsha S. Ivins (pink cap), and MS Franklin R. Chang-Diaz; and (front to back in the background) Commander Loren J. Shriver, Pilot Andrew M. Allen, backup Italian Payload Specialist Umberto Guidoni, and Italian Payload Specialist Franco Malerba. A fire fighter training instructor stands between the two lines of crewmembers and the two hoses.

  20. Bruner's Search for Meaning: A Conversation between Psychology and Anthropology.

    PubMed

    Mattingly, Cheryl; Lutkehaus, Nancy C; Throop, C Jason

    2008-03-01

    We introduce a special issue of Ethos devoted to the work of Jerome Bruner and his careerlong attempts to seek innovative ways to foster a dialogue between psychology and anthropology. The articles in this special issue situate Bruner's meaning-centered approach to psychology and his groundbreaking work on narrative in the broader context of the developmental trajectory of both of fields of inquiry. Bruner's work has been enormously influential in the subfields of cultural psychology and psychological anthropology, especially because of his important contributions to our understanding of the intimate relationship between culture and mind. We examine Bruner's past and ongoing engagement with such luminary figures as Lev Vygotsky, Jean Piaget, Alfred Kroeber, Claude Lévi-Strauss, and Clifford Geertz to highlight points of convergence and tension between his version of cultural psychology and contemporary theorizing and practice in psychological anthropology. We also review his practical and theoretical contributions to the fields of medicine, law, and education. PMID:20706551

  1. Cosmic Perspectives

    NASA Astrophysics Data System (ADS)

    Biswas, S. K.; Mallik, D. C. V.; Vishveshwara, C. V.

    2008-07-01

    1. Astronomy in ancient and medieval China Joseph Needham; 2. Indian astronomy: an historical perspective B. V. Subbarayappa; 3. Making of astronomy in ancient India Debiprasad Chattopadhyaya; 4. The impact of astronomy on the development of western science Jean-Claude Pecker; 5. Man and the Universe Hubert Reeves; 6. Understanding the Universe - challenges and directions in modern observational astronomy Harlan Smith, Jr: 7. Frontiers in cosmology Fred Hoyle; 8. Did the Universe originate in a big bang? Jayant Narlikar; 9. The dark matter problem Bernard Carr; 10. Geometry and the Universe C. V. Vishveshwara; 11. The origin and evolution of life Cyril Ponnamperuma; 12. The anthropic principle: self selection as an adjunct to natural selection Brandon Carter; 13. Astrology and science: an examination of the evidence Ivan Kelly, Roger Culver and Peter Loptson; 14. Astronomy and science fiction Allen Janis.

  2. An Englishman abroad: Charles Blagden's visit to Paris in 1783.

    PubMed

    Fauque, Danielle M E

    2008-12-20

    Once the preliminaries of peace had been signed in January 1783, after the war of American independence, exchanges between British and French men of science resumed their normal course. On a visit to Paris in 1783, the francophile Charles Blagden (with the encouragement of Joseph Banks) made a number of contacts that fostered relations between the Royal Society and the Académie royale des sciences. In the course of this and several subsequent visits to France, Blagden became especially intimate with the chemist Claude-Louis Berthollet. His correspondence, now in the Royal Society, is a rich source for our understanding of some of the leading scientific debates of the day, in particular concerning the nature of water, which forms the main subject of this article. PMID:19244920

  3. [Hatred of foreigners and purity--current aspects of an illusion. Social psychological and psychoanalytic considerations].

    PubMed

    Heim, R

    1992-08-01

    This study draws upon both Carlo Ginzburg's procedures for establishing and preserving (historical) evidence and Claude Lévi-Strauss' structuralist approach with its analysis of "primitive" mythologies to demonstrate that binary coding of the social domain is an all-pervasive structural principle. Heim's intention in this is to show that (present-day) xenophobia and racism are the products of a phantasm centering around the division of the world into pure and impure. The author brings into alignment collective fantasies about the homogeneity of the "body politic" with a form of primary narcissism which, if it is to preserve the illusion of original purity, is forced to externalize instinctual urges experienced as heterogeneous and unpleasurable and project them onto "foreigners" and things foreign. PMID:1509096

  4. The New Physics

    NASA Astrophysics Data System (ADS)

    Fraser, Gordon

    2009-08-01

    Introduction Gordon Fraser; Part I. Matter and the Universe: 1. Cosmology Wendy Freedman and Rocky Kolb; 2. Gravity Ronald Adler; 3. Astrophysics Arnon Dar; 4. Particles and the standard model Chris Quigg; 5. Superstrings Michael Green; Part II. Quantum Matter: 6. Atoms and photons Claude Cohen-Tannoudji and Jean Dalibard; 7. The quantum world of ultra-cold atoms Christopher Foot and William Phillips; 8. Superfluidity Henry Hall; 9. Quantum phase transitions Subir Sachdev; Part III. Quanta in Action: 10. Quantum entanglement Anton Zeilinger; 11. Quanta, ciphers and computers Artur Ekert; 12. Small-scale structure and nanoscience Yoseph Imry; Part IV. Calculation and Computation: 13. Nonlinearity Henry Abarbanel; 14. Complexity Antonio Politi; 15. Collaborative physics, e-science and the grid Tony Hey and Anne Trefethen; Part V. Science in Action: 16. Biophysics Cyrus Safinya; 17. Medical physics Nicolaj Pavel; 18. Physics and materials Robert Cahn; 19. Physics and society Ugo Amaldi.

  5. The New Physics

    NASA Astrophysics Data System (ADS)

    Fraser, Gordon

    2006-04-01

    Introduction Gordon Fraser; Part I. Matter and the Universe: 1. Cosmology Wendy Freedman and Rocky Kolb; 2. Gravity Ronald Adler; 3. Astrophysics Arnon Dar; 4. Particles and the standard model Chris Quigg; 5. Superstrings Michael Green; Part II. Quantum Matter: 6. Atoms and photons Claude Cohen-Tannoudji and Jean Dalibard; 7. The quantum world of ultra-cold atoms Christopher Foot and William Phillips; 8. Superfluidity Henry Hall; 9. Quantum phase transitions Subir Sachdev; Part III. Quanta in Action: 10. Quantum entanglement Anton Zeilinger; 11. Quanta, ciphers and computers Artur Ekert; 12. Small-scale structure and nanoscience Yoseph Imry; Part IV. Calculation and Computation: 13. Nonlinearity Henry Abarbanel; 14. Complexity Antonio Politi; 15. Collaborative physics, e-science and the grid Tony Hey and Anne Trefethen; Part V. Science in Action: 16. Biophysics Cyrus Safinya; 17. Medical physics Nicolaj Pavel; 18. Physics and materials Robert Cahn; 19. Physics and society Ugo Amaldi.

  6. RETRACTED: Impacts of past climate variability on marine ecosystems: Lessons from sediment records

    NASA Astrophysics Data System (ADS)

    Emeis, Kay-Christian; Finney, Bruce P.; Ganeshram, Raja; Gutiérrez, Dimitri; Poulsen, Bo; Struck, Ulrich

    2010-02-01

    This article has been retracted at the request of the Editor-in-Chief and Author. Please see Elsevier Policy on Article Withdrawal ( http://www.elsevier.com/locate/withdrawalpolicy). Reason: Paragraph 3.3 of this article contains text (verbatim) that had already appeared in a book chapter "Variability from scales in marine sediments and other historical records" by David B. Field, Tim R. Baumgartner, Vicente Ferreira, Dimitri Gutierrez, Hector Lozano-Montes, Renato Salvatteci and Andy Soutar. The book is entitled "Climate Change and Small Pelagic Fish", 2009, edited by Dave Checkley, Claude Roy, Jurgen Alheit, and Yoshioki Oozeki (Cambridge University Press; 2009).The authors would like to apologize for this administrative error on their part.

  7. [How to become a pharmacist via the medical juries, during the Consulate and the Empire].

    PubMed

    Lafont, Olivier

    2015-09-01

    The law of Germinal an XI organized the education of pharmacists. It offered two different pathways to become a pharmacist. The first one needed three years in a pharmacy followed by three years of courses in a School of Pharmacy (located in Paris, Montpellier or Strasbourg) and the examination had to be passed in the School. The second one needed eight years in a pharmacy followed by an examination in front of a Medical jury. Medical juries were organized in every department and were composed by three physicians and four pharmacists. An interesting document, a book gathering together all the preparations realized during years 1811, 1812, 1813, collected by Claude Duméril in many departments, will allow to study what had been asked to the candidates in Rouen, in 1813, and what were reference pharmacopoeias used. PMID:26529887

  8. Bandwidth efficient coding: Theoretical limits and real achievements. Error control techniques for satellite and space communications

    NASA Technical Reports Server (NTRS)

    Costello, Daniel J., Jr.; Courturier, Servanne; Levy, Yannick; Mills, Diane G.; Perez, Lance C.; Wang, Fu-Quan

    1993-01-01

    In his seminal 1948 paper 'The Mathematical Theory of Communication,' Claude E. Shannon derived the 'channel coding theorem' which has an explicit upper bound, called the channel capacity, on the rate at which 'information' could be transmitted reliably on a given communication channel. Shannon's result was an existence theorem and did not give specific codes to achieve the bound. Some skeptics have claimed that the dramatic performance improvements predicted by Shannon are not achievable in practice. The advances made in the area of coded modulation in the past decade have made communications engineers optimistic about the possibility of achieving or at least coming close to channel capacity. Here we consider the possibility in the light of current research results.

  9. Potential of proposed open-cycle OTEC experiments to achieve net power

    SciTech Connect

    Link, H F; Parsons, B K

    1986-06-01

    Researchers at the Solar Energy Research Institute (SERI) conducted systems analysis studies to determine the potential of various experiments to produce net power using the Claude open-cycle ocean thermal energy conversion (OTEC) power system. The proposed experiment test site is to be the Natural Energy Laboratory of Hawaii at Keahole Point. We found that net power is unlikely to be produced in experiment sizes that use less than about 195 kg/s (3000 gpm) of cold water, and that flow rates of 420 kg/s (6500 gpm) are necessary to achieve a net-power production of at least one-half the gross-power output of the experiment.

  10. Dempster-Shafer theory and connections to information theory

    NASA Astrophysics Data System (ADS)

    Peri, Joseph S. J.

    2013-05-01

    The Dempster-Shafer theory is founded on probability theory. The entire machinery of probability theory, and that of measure theory, is at one's disposal for the understanding and the extension of the Dempster-Shafer theory. It is well known that information theory is also founded on probability theory. Claude Shannon developed, in the 1940's, the basic concepts of the theory and demonstrated their utility in communications and coding. Shannonian information theory is not, however, the only type of information theory. In the 1960's and 1970's, further developments in this field were made by French and Italian mathematicians. They developed information theory axiomatically, and discovered not only the Wiener- Shannon composition law, but also the hyperbolic law and the Inf-law. The objective of this paper is to demonstrate the mathematical connections between the Dempster Shafer theory and the various types of information theory. A simple engineering example will be used to demonstrate the utility of the concepts.

  11. STS-103 Mission Highlights Resource Tape (2 of 2)

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The STS-103 flight crew, Commander Curtis L. Brown, Pilot Scott J. Kelly, Mission Specialists Steven L. Smith, C. Michael Foale, John M. Grunsfeld, Claude Nicollier, and Jean-Francois Clervoy, are seen passing over the Yucatan and Florida Peninsulas. Smith and Grunsfeld replace and change the S-band single transmission cables during the third and final space walk of this mission. Crewmembers are also seen taking video documentation of the solar arrays. Footage presented includes the release of the Hubble Space Telescope, thruster firing and orbit adjust burn over the Central Indian Ocean and Australia. Also shown is the night landing of Discovery at Kennedy Space Center, crew departure from the vehicle, and short statements made by the crew. This is tape 2 of 2; tape 1 has a report number of NONP-NASA-VT-2000036030.

  12. Thermodynamic aspects of small 4.2-K cryocoolers

    NASA Astrophysics Data System (ADS)

    Pirtle, F. W.; Lessard, P. A.; Kaufman, J. M.; Kerney, P. J.

    Advantages regarding a use of superconducting electronic devices are related to potential benefits in size, weight, accuracy, sensitivity, and reproducibility. For the employment of such devices, suitable cryogenic systems are needed. As closed cycle coolers have advantages with respect to potential size, weight, and longevity, an investigation has been performed for the evaluation of different closed cycle system options from a thermodynamic point of view. A survey of available technology is provided, and aspects of thermodynamic optimization are explored, taking into account the single engine Claude cycle, regenerative cycles with J-T loops, and a comparison of the total power requirements for the three cycles. A study is conducted of wet (two-phase) expanders, cold gas compressors, and ejectors to determine potential improvements to the J-T sections of the various cycles.

  13. STS-103 Commander Brown arrives at KSC for launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Commander Curtis L. Brown Jr. smiles on his arrival at the Shuttle Landing Facility aboard a T-38 jet aircraft. He joins other crew members Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, for pre-launch preparations on mission STS-103 aboard Space Shuttle Discovery. Nicollier and Clervoy are with the European Space Agency. The mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 11 at 12:13 a.m. EST from Launch Pad 39B. Discovery is expected to land at KSC Monday, Dec. 20, at 9:21 p.m. EST.

  14. STS-103 Commander Brown suits up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. is suited up and ready to go for the second launch attempt of Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Brown and fellow crew members Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  15. STS-103 Commander Brown arrives at SLF aboard a T-38 jet for TCDT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. is happy to arrive at Kennedy Space Center to begin Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Also participating are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, with the European Space Agency, and Jean-Frangois Clervoy of France, also with the European Space Agency. The mission, to service the Hubble Space Telescope, is targeted for launch Dec. 6 at 2:37 a.m. EST aboard Space Shuttle Discovery.

  16. [Glorification of forgotten famous chemists: the medals of the Stanislas Limousin Committee].

    PubMed

    Dillemann, G

    1996-01-01

    A Committee created in 1938 by Pr Goris decided to honour Stanislas Limousin--a dispensing chemist who invented, among other things, medicinal Cachets and pharmaceutical vials--by placing a medallion bearing his effigy upon the house where he was born in Ardentes. Ten years later, this Committee considered that quite a few other dispensing chemists deserved the same honour and selected four of them: Eugène Choay, Charles Tanret, Emile Boudier and Claude Nativelle: the aim of the author was find out whether those medallions had really been affixed on the respective birth places of these pharmacists and if they were still in place. It is the case for the first two of them. Concerning Boudier, his medallion was affixed on his pharmacy in Montmorency and is still there. As for Nativelle, his medallion, if ever affixed, was laid down and recently found again an attic of the faculty of pharmacy. PMID:8734335

  17. Hearing Science in Mid-Eighteenth-Century Britain and France

    PubMed Central

    Gouk, Penelope; Sykes, Ingrid

    2011-01-01

    Benjamin Martin, the English natural philosopher, and Claude-Nicolas Le Cat, the French surgeon, both published important work on auditory physiology and function in the mid-eighteenth century. Despite their different backgrounds, there was consensus between the two scholars on key principles of hearing research, most notably the importance of the inner ear in relation to auditory perception. Martin's work (1755 [1763?]) drew directly on the surgical work of Le Cat (1741) to demonstrate the importance of the auditory mechanism in listening processes. Le Cat's interest in the ear, however, came in turn from his interest in surgical anatomy. Martin used Le Cat's elegant designs as a tool for the vivid communication of auditory function to a popular, fee-paying audience. The meeting of two very different minds through intellectual agreement and material transfer demonstrates the way in which principles of hearing science were established in the Enlightenment period. PMID:20634220

  18. Evolution of biological information.

    PubMed

    Schneider, T D

    2000-07-15

    How do genetic systems gain information by evolutionary processes? Answering this question precisely requires a robust, quantitative measure of information. Fortunately, 50 years ago Claude Shannon defined information as a decrease in the uncertainty of a receiver. For molecular systems, uncertainty is closely related to entropy and hence has clear connections to the Second Law of Thermodynamics. These aspects of information theory have allowed the development of a straightforward and practical method of measuring information in genetic control systems. Here this method is used to observe information gain in the binding sites for an artificial 'protein' in a computer simulation of evolution. The simulation begins with zero information and, as in naturally occurring genetic systems, the information measured in the fully evolved binding sites is close to that needed to locate the sites in the genome. The transition is rapid, demonstrating that information gain can occur by punctuated equilibrium. PMID:10908337

  19. Forces and Motion: Dynamics of the Tethered Satellite

    NASA Technical Reports Server (NTRS)

    1994-01-01

    In this 'Lift off to Learning' series, Loren Shriver, commander of STS 46, and the other members of the mission (Claude Nicollier, Marsha Ivins, Andrew Allen, Jeffrey Hoffman, Franklin Chiang-Diaz, and Franco Maerba) use computer graphics, and physical experiments to explain how the tethered satellite to be deployed during their mission will be raised, how it works, the influence of the Shuttle on the satellite and the satellite's influence on the Shuttle's orbit, the gravitational effects, and other effects concerning the Theoretical Physics used to plan this mission (gravity gradient force, center of mass, angular momentum, centrifugal force, and coriolis effect). This video ends with a discussion of the technology transfer and utilization of this tethered satellite concept and design.

  20. Mission Specialist Smith is suited and ready for launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Operations and Checkout Building, STS-103 Mission Specialist Steven L. Smith signals he is suited up and ready for launch. Other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists C. Michel Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 8-day, 21-hour mission, Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:30 p.m. EST.

  1. [THE SCIENTIFIC REVOLUTION IN MEDICINE OF THE LAST QUARTER OF XIX-FIRST HALF OF XX CENTURIES. REPORT II. THE OUTSET OF REVISION OF MEDICAL SCIENCE].

    PubMed

    Stochik, A M; Zatravkin, S N

    2015-01-01

    The article affirms that onset of revision of picture of analyzed reality, methodological approaches to studying of vital activity of human organism and philosophical basics of medical science refers to 1878 and is related to publishing of "The course of general physiology" by French physiologist Claude Bernard. The implemented analysis of the text of this work permit to establish that C. Bernard undertook an attempt to introduce conception of human organism as a processing system being self-reproduced as. a result of interaction with environment due to mechanisms of self-regulation. The necessity was substantiated to make experiment the leading method of cognition of vital activity. The living wholeness (organism, cell) was proposed to be an object of experimentation. In this living wholeness its natural capacities to self-regulation of main vital processes can be preserved at its maximum. The new senses were introduced into ontological categories of thing, process, causality, portion and whole. PMID:26399073

  2. Messier, Copernicus, Flamsteed: The SAF Rare-Book Collection in Paris

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.

    2014-01-01

    The historic books belonging to the Société Astronomique de France, founded by Camille Flammarion in 1887, are located partly in Paris and partly at the Flammarion site in Juvisy, a Paris suburb. Their holdings include first editions of Copernicus's De Revolutionibus and of Flamsteed's star atlas, as well as Messier's own copy of his 1783 and 1784 papers with his handwritten comments and additions. I will describe the fruitless search for a Bevis atlas and the circumstances that led me to inspect these treasures. I thank David Valls-Gabaud and Philippe Morel of the Société Astronomique de France for their hospitality in Paris, Jean-Claude Pecker, and Owen Gingerich for his prior work on Messier's catalogue.

  3. Growing Evidence about the Relationship between Vessel Dissection and Scuba Diving.

    PubMed

    Brajkovic, Simona; Riboldi, Giulietta; Govoni, Alessandra; Corti, Stefania; Bresolin, Nereo; Comi, Giacomo Pietro

    2013-01-01

    Carotid and vertebral artery dissection are relatively frequent and risky conditions. In the last decade, different patients with extracranial (and in 1 case also intracranial) dissections associated with the practice of scuba diving were reported. The connection between the two conditions has not been fully explained so far. In the present article, we report the case of a patient presenting with Claude Bernard-Horner syndrome and homolateral XII cranial nerve palsy, manifesting a few days after diving in the cold water of a lake. The patient ended up having internal carotid artery dissection associated with the formation of a pseudoaneurysm. Here, we offer a summary of all cases reported in the literature about scuba diving and arterial dissection, and provide a critical discussion about which scuba diving-related factors can trigger the dissection of cervical vessels. PMID:24163671

  4. STS-61 crewmembers training with the Remote Manipulator System

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Remote Manipulator System (RMS) eases a mannequin representing an astronaut into position for an STS-61 Hubble Space Telescope (HST) servicing task in the Space Shuttle mockup and integration laboratory at JSC (35699, 35703); Wide-angle view of the RMS easing a mannequin into position for work on the HST mock-up in bldg 9N (35700-1); Swiss scientist Claude Nicollier, mission specialist, works the control of the RMS during a training session in the manipulator development facility (MDF) in JSC's Shuttle mock-up and integration laboratory. Astronaut Kenneth D. Bowersox (left), pilot, is among the other crewmembers in training for the STS-61 HST servicing mission (35702).

  5. Molecular structure and pathophysiological roles of the Mitochondrial Calcium Uniporter.

    PubMed

    Mammucari, Cristina; Raffaello, Anna; Vecellio Reane, Denis; Rizzuto, Rosario

    2016-10-01

    Mitochondrial Ca(2+) uptake regulates a wide array of cell functions, from stimulation of aerobic metabolism and ATP production in physiological settings, to induction of cell death in pathological conditions. The molecular identity of the Mitochondrial Calcium Uniporter (MCU), the highly selective channel responsible for Ca(2+) entry through the IMM, has been described less than five years ago. Since then, research has been conducted to clarify the modulation of its activity, which relies on the dynamic interaction with regulatory proteins, and its contribution to the pathophysiology of organs and tissues. Particular attention has been placed on characterizing the role of MCU in cardiac and skeletal muscles. In this review we summarize the molecular structure and regulation of the MCU complex in addition to its pathophysiological role, with particular attention to striated muscle tissues. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26968367

  6. Mendelevium: The Way It Was

    SciTech Connect

    2013-11-05

    A reel of black & white film shot nearly 60 years ago has surfaced at Berkeley Lab, depicting the discovery of Mendelevium - or Element 101 - as reenacted by some of the legendary scientists who did the actual work at that time. Since the 1940s, Berkeley Lab scientists were locked in a race to synthesize new elements, and more often than not, they came out winners. Sixteen elements, most of them in the actinide series at the bottom of the periodic table, were discovered and synthesized by its researchers. Retired Berkeley Lab physicist Claude Lyneis found the reel in a box of dusty and deteriorating films slated for disposal. Using digital editing skills he acquired to make videos of his son's lacrosse team, Lyneis has produced and narrated an excerpt of this nearly-lost footage. It is an entertaining and informative look at the pioneering physics performed at UC Berkeley and Lawrence Berkeley National Laboratory's hillside campus.

  7. Let it burn: distinguishing inflammable airs 1766-1790.

    PubMed

    Tomory, Leslie

    2009-11-01

    The issue of the number of species of inflammable air was debated particularly in the period 1777-1786. The work of Henry Cavendish in 1766 and Alessandro Volta in 1777 in characterising two species of inflammable air set the stage for the work of other chemists, particularly in Paris, as they debated this question, mostly concerning heavy inflammable air. Different ways of generating gases were discovered up to 1783, when the synthesis of water and the proposal of carbon as an element created a framework for the question to be answered. In 1785-1786, Claude-Louis Berthollet reported the composition of heavy inflammable air and volatile alkali, while Philippe Gengembre analysed phosphorated hydrogen and hepatic air. In the end, it was the new chemical nomenclature of 1787 that spread their results widely. PMID:20506705

  8. An analysis of concert saxophone vibrato through the examination of recordings by eight prominent soloists

    NASA Astrophysics Data System (ADS)

    Zinninger, Thomas

    This study examines concert saxophone vibrato through the analysis of several recordings of standard repertoire by prominent soloists. The vibrato of Vincent Abato, Arno Bornkamp, Claude Delangle, Jean-Marie Londeix, Marcel Mule, Otis Murphy, Sigurd Rascher, and Eugene Rousseau is analyzed with regards to rate, extent, shape, and discretionary use. Examination of these parameters was conducted through both general observation and precise measurements with the aid of a spectrogram. Statistical analyses of the results provide tendencies for overall vibrato use, as well as the effects of certain musical attributes (note length, tempo, dynamic, range) on vibrato. The results of this analysis are also compared among each soloist and against pre-existing theories or findings in vibrato research.

  9. Information theory in systems biology. Part II: protein-protein interaction and signaling networks.

    PubMed

    Mousavian, Zaynab; Díaz, José; Masoudi-Nejad, Ali

    2016-03-01

    By the development of information theory in 1948 by Claude Shannon to address the problems in the field of data storage and data communication over (noisy) communication channel, it has been successfully applied in many other research areas such as bioinformatics and systems biology. In this manuscript, we attempt to review some of the existing literatures in systems biology, which are using the information theory measures in their calculations. As we have reviewed most of the existing information-theoretic methods in gene regulatory and metabolic networks in the first part of the review, so in the second part of our study, the application of information theory in other types of biological networks including protein-protein interaction and signaling networks will be surveyed. PMID:26691180

  10. Information theory in systems biology. Part I: Gene regulatory and metabolic networks.

    PubMed

    Mousavian, Zaynab; Kavousi, Kaveh; Masoudi-Nejad, Ali

    2016-03-01

    "A Mathematical Theory of Communication", was published in 1948 by Claude Shannon to establish a framework that is now known as information theory. In recent decades, information theory has gained much attention in the area of systems biology. The aim of this paper is to provide a systematic review of those contributions that have applied information theory in inferring or understanding of biological systems. Based on the type of system components and the interactions between them, we classify the biological systems into 4 main classes: gene regulatory, metabolic, protein-protein interaction and signaling networks. In the first part of this review, we attempt to introduce most of the existing studies on two types of biological networks, including gene regulatory and metabolic networks, which are founded on the concepts of information theory. PMID:26701126

  11. Noteworthy Chemistry of Chloroform.

    PubMed

    Alston, Theodore A

    2016-07-01

    Inhaled chloroform anesthesia was introduced in 1847. Soon thereafter, the chemical reactivity of aerobically heated chloroform permitted John Snow and Claude Bernard to do seminal experiments in the assay of drug levels and drug metabolism. However, it was not widely appreciated until a clinical mishap in 1899 that thermal decomposition generated significant levels of toxic phosgene from air-polluting quantities of chloroform in poorly ventilated operating rooms that were illuminated by flames. Phosgene is also generated metabolically from chloroform. A clue appeared in the 1950s when subanesthetic traces of inhaled chloroform proved accidentally lethal to strains of male mice spontaneously expressing high levels of chloroform-metabolizing enzymes. Furthermore, in microbial experiments of 1967, the reactive chloroform molecule was inadvertently discovered to selectively inactivate vitamin B12-dependent enzymes. Chloroform can also activate enzymes. As a solvent, it was serendipitously found in 1903 to activate what is now known as plasminogen to plasmin. PMID:27480474

  12. STS-103 Crew at Breakfast, Suiting, Departing O&C

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The Hubble Space Telescope (HST) team is preparing for NASA's third scheduled service call to Hubble. This mission, STS-103, will launch from Kennedy Space Center aboard the Space Shuttle Discovery. The seven flight crew members for STS-103 are: Commander Curtis L. Brown (his sixth flight), Pilot Scott J. Kelly and European Space Agency (ESA) astronaut Jean-Francois Clervoy (his third flight) will join space walkers Steven L. Smith (his third flight), C. Michael Foale (his fifth flight), John M. Grunsfeld (his third flight) and ESA astronaut Claude Nicollier (his fourth flight). This current video presents a live footage of the seven STS-103 crewmembers eating breakfast, suiting, and departing the O&C (Operations and Checkout) before the 6:50 p.m. lift-off.

  13. Mission Specialist Nicollier gets help suiting up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Operations and Checkout Building, STS-103 Mission Specialist Claude Nicollier of Switzerland waves while having his launch and entry suit checked by a suit techician during final launch preparations. Other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 8-day, 21-hour mission, Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:30 p.m. EST.

  14. Mission Specialist Foale gets help suiting up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Operations and Checkout Building, STS-103 Mission Specialist C. Michel Foale (Ph.D.) smiles as his launch and entry suit is checked by a suit techician during final launch preparations. Other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 8-day, 21-hour mission, Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:30 p.m. EST.

  15. Mission Specialist Grunsfeld gets help suiting up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Operations and Checkout Building, STS-103 Mission Specialist John M. Grunsfeld (Ph.D.) is assisted by a suit technician in donning his launch and entry suit during final launch preparations. Other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 8-day, 21-hour mission, Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:30 p.m. EST.

  16. Cosmic Perspectives

    NASA Astrophysics Data System (ADS)

    Biswas, S. K.; Mallik, D. C. V.; Vishveshwara, C. V.

    1989-09-01

    1. Astronomy in ancient and medieval China Joseph Needham; 2. Indian astronomy: an historical perspective B. V. Subbarayappa; 3. Making of astronomy in ancient India Debiprasad Chattopadhyaya; 4. The impact of astronomy on the development of western science Jean-Claude Pecker; 5. Man and the Universe Hubert Reeves; 6. Understanding the Universe - challenges and directions in modern observational astronomy Harlan Smith, Jr: 7. Frontiers in cosmology Fred Hoyle; 8. Did the Universe originate in a big bang? Jayant Narlikar; 9. The dark matter problem Bernard Carr; 10. Geometry and the Universe C. V. Vishveshwara; 11. The origin and evolution of life Cyril Ponnamperuma; 12. The anthropic principle: self selection as an adjunct to natural selection Brandon Carter; 13. Astrology and science: an examination of the evidence Ivan Kelly, Roger Culver and Peter Loptson; 14. Astronomy and science fiction Allen Janis.

  17. List of participants at SIDE IV meeting, Tokyo, 27 November--1 December 2000

    NASA Astrophysics Data System (ADS)

    2001-12-01

    Mark J Ablowitz, Vsevolod Adler, Mark Alber, Said Belmehdi, Marco Boiti, Claude Brezinski, R Bullough, Y M Chiang, Theodore Chihara, Peter A Clarkson, Robert Conte, Adam Doliwa, Vladimir Dorodnitsyn, Mitsuaki Eguchi, Claire Gilson, Basil Grammaticos, Valeri Gromak, Rod Halburd, Koji Hasegawa, Jarmo Hietarinta, Ryogo Hirota, Xing Biao Hu, M Idzumi, J Inoguchi, Hiroya Ishikara, Mourad Ismail, Shin Isojima, Kenichi Ito, Yoshiaki Itoh, Masashi Iwasaki, Klara Janglajew, Michio Jimbo, Nalini Joshi, Kenji Kajiwara, Saburo Kakei, Masaru Kamata, Satoshi Kamei, Rinat Kashaev, Shingo Kawai, Taeko Kimijima, K Kimura, Anatol Kirillov, Koichi Kondo, Boris Konopelchenko, Martin Kruskal, Atsuo Kuniba, Wataru Kunishima, Franklin Lambert, Serguei Leble, Decio Levi, Shigeru Maeda, Manuel Manas, Ken-Ichi Maruno, Tetsu Masuda, J Matsukidaira, Atsushi Matsumiya, Shigeki Matsutani, Yukitaka Minesaki, Mikio Murata, Micheline Musette, Atsushi Nagai, Katsuya Nakagawa, Atsushi Nakamula, Akira Nakamura, Yoshimasa Nakamura, Frank Nijhoff, J J C Nimmo, Katsuhiro Nishinari, Michitomo Nishizawa, A Nobe, Masatoshi Noumi, Yaeko Ohsaki, Yasuhiro Ohta, Kazuo Okamoto, Alexandre Orlov, Naoki Osada, Flora Pempinelli, Spiro Pyrlis, Reinout Quispel, Orlando Ragnisco, Alfred Ramani, Jean-Pierre Ramis, Andreas Ruffing, Simon Ruijsenaars, Satoru Saito, Noriko Saitoh, Hidetaka Sakai, Paulo Santini, Narimasa Sasa, Ryu Sasaki, Yoshikatsu Sasaki, Junkichi Satsuma, Sergei Sergeev, Nobuhiko Shinzawa, Evgueni Sklyanin, Juris Suris, Norio Suzuki, Yukiko Tagami, Katsuaki Takahashi, Daisuke Takahashi, Tomoyuki Takenawa, Yoshiro Takeyama, K M Tamizhmani, T Tamizhmani, Kouichi Toda, Morikatsu Toda, Tetsuji Tokihiro, Takayuki Tsuchida, Yohei Tsuchiya, Teruhisa Tsuda, Satoru Tsujimoto, Walter Van Assche, Claude Viallet, Luc Vinet, Shinsuke Watanabe, Yoshihida Watanabe, Ralph Willox, Pavel Winternitz, Yasuhiko Yamada, Yuji Yamada, Jin Yoneda, Haruo Yoshida, Katsuhiko Yoshida, Daisuke Yoshihara, Fumitaka Yura, J

  18. Assessment of prognostic scores in brain metastases from breast cancer

    PubMed Central

    Tabouret, Emeline; Metellus, Philippe; Gonçalves, Anthony; Esterni, Benjamin; Charaffe-Jauffret, Emmanuelle; Viens, Patrice; Tallet, Agnés

    2014-01-01

    Background Breast cancer (BC) is the second most common cause of brain metastases (BM). Optimal management of BM from BC is still debated. In an attempt to provide appropriate treatment and to assist with optimal patient selection, several specific prognostic classifications for BM from BC have been established. We evaluated the prognostic value and validity of the 6 proposed scoring systems in an independent population of BC patients with BM. Methods We retrospectively reviewed all consecutive BC patients referred to our institution for newly diagnosed BM between October 1995 and July 2011 (n = 149). Each of the 6 scores proposed for BM from BC (Sperduto, Niwinska, Park, Nieder, Le Scodan, and Claude) was applied to this population. The discriminative ability of each score was assessed using the Brier score and the C-index. Individual prognostic values of clinical and histological factors were analyzed using uni- and multivariate analyses. Results Median overall survival was 15.1 months (95% CI,11.5–18.7). Sperduto-GPA (P < .001), Nieder (P < .001), Park (P < .001), Claude (P < .001), Niwinska (P < .001), and Le Scodan (P = .034) scores all showed significant prognostic value. The Nieder score showed the best discriminative ability (C-index, 0.672; Brier score error reduction, 16.1%). Conclusion The majority of prognostic scores were relevant for patients with BM from BC in our independent population, and the Nieder score seems to present the best predictive value but showed a relatively low positive predictive value. Thus, these results remain insufficient and challenge the routine use of these scoring systems. PMID:24311640

  19. Feasibility study on earthquake early warning application to schools: the example of the ITIS 'E. Majorana', Somma Vesuviana, Naples (Italy)

    NASA Astrophysics Data System (ADS)

    Emolo, Antonio; Zollo, Aldo; Picozzi, Matteo; Martino, Claudio; Elia, Luca; Verderame, Gerardo; De Risi, Maria Teresa; Ricci, Paolo; Lombardi, Anna; Bindi, Dino; Parolai, Stefano; Boxberger, Tobias; Miranda, Nicola

    2014-05-01

    One of the main objective of the WP7 (Strategic Applications and Capacity Building) in the framework of the REAKT-Strategies and tools for Real Time Earthquake RisK ReducTion FP7 European project, is to evaluate the effectiveness of EEW and real-time risk assessment procedures in reducing seismic risk to various industrial partners and end-users. In the context of the REAKT project, the AMRA-RISSCLab group is engaged in a feasibility study on the application of earthquake early-warning procedures in two high schools located in the Irpinia region (South Italy), an area that in the 1980 was struck by a magnitude 6.9 earthquake. In this work we report on the activities carried out during the last 24 Months at the school ITIS 'E. Majorana', located in Somma Vesuviana, a village in the neighbourhood of Naples. In order to perform a continuous seismic monitoring of the site, which includes a rather complex structure building, 5 accelerometric stations have been installed in different part of the school. In particular, a 24-bit ADC (Sigma/Delta) Agecodagis-Kefren data-logger has been installed with a Guralp CMG-5TC accelerometer with a 0.25g full-scale in the school courtyard, while 4 SOSEWIN sensors have been also installed at different locations within the building. Commercial ADSL lines provide transmission of real-time data to the EEW centre. Data streams are now acquired in real-time in the PRESToPlus (regional and on-site, threshold-based early-warning) software platform [1]. The recent December 29, 2013 M 5.1 Monti del Matese Earthquake, gave us the unique opportunity to use real strong motion data to test the performance of threshold-based early warning method at the school. The on-site method [2] aims to define alert levels at the monitored site. In particular, at each station the characteristic P-waves period (τc) and the peak displacement (Pd) are measured on the initial P-wave signal. They are compared with threshold values, previously established through an

  20. Feasibility study of a nation-wide Early Warning System: the application of the EEW software PRESTo on the Italian Strong Motion Network (RAN)

    NASA Astrophysics Data System (ADS)

    Zollo, Aldo; Picozzi, Matteo; Elia, Luca; Martino, Claudio; Brondi, Piero; Colombelli, Simona; Emolo, Antonio; Festa, Gaetano; Marcucci, Sandro

    2014-05-01

    The past two decades have witnessed a huge progress in the development, implementation and testing of Earthquakes Early Warning Systems (EEWS) worldwide, as the result of a joint effort of the seismological and earthquake engineering communities to set up robust and efficient methodologies for the real-time seismic risk mitigation. The leading experience of the operational early warning system implemented by the Japan Meteorological Agency showed the effectiveness of a combined onsite and network-based approach to rapidly broadcast the rapid warning after a potential damaging earthquake. At the nation-wide scale, the Japanese system makes use of real-time data streamed by the extremely dense accelerograph array (about 1000 seismic instruments) deployed across Japan. With more than 750 accelerometric stations installed over all the active seismic zones, target cities and strategic infrastructures, Italy has the potential for a nation-wide early warning system, although the communication network and data sharing must be expanded and improved. A significant number of these stations are nodes of the RAN (Italian Accelerometric Network) managed by the Italian national emergency management department (Dipartimento della Protezione Civile, DPC), whose data are used for emergency response services. In the framework of the REAKT-Strategies and tools for Real Time Earthquake RisK ReducTion FP7 European project, the AMRA-RISSCLab group is engaged in a feasibility study on the implementation of the EEW software PRESTo earthquake early warning platforms on the Italian accelerometric network (RAN) PRESTo (PRobabilistic and Evolutionary early warning SysTem) is a highly configurable and easily portable platform for Earthquake Early Warning. The system processes the live accelerometric streams from the stations of a seismic network to promptly provide probabilistic and evolutionary estimates of location and magnitude of detected earthquakes while they are occurring, as well as

  1. Interrelationships between information and energy using knowledge management tools

    SciTech Connect

    Lizcano, D. E-mail: mariaaurora.martinez@udima.es; Martínez, A. María E-mail: mariaaurora.martinez@udima.es

    2014-10-06

    Edward Fredkin was an enthusiastic advocate of information-based theoretical physics, who, in the early 1980s, proposed a new theory of physics based on the idea that the universe is ultimately composed of software. According to Fredkin, reality should be considered as being composed not of particles, matter and forces or energy but of bits of data or information modified according to computational rules. Fredkin went on to demonstrate that, while energy is necessary for storing and retrieving information, it can be arbitrarily reduced in order to carry out any particular instance of information processing, and this operation does not have a lower bound. This implies that it is information rather than matter or energy that should be considered at the ultimate fundamental constituent of reality. This possibility had already been suggested by other scientists. Norbert Wiener heralded a fundamental shift from energy to information and suggested that the universe was founded essentially on the transformation of information, not energy. However, Konrad Zuse was the first, back in 1967, to defend the idea that a digital computer is computing the universe. Richard P. Feynman showed this possibility in a similar light in his reflections on how information related to matter and energy. Other pioneering research on the theory of digital physics was published by Kantor in 1977 and more recently by Stephen Wolfram in 2002, who thereby joined the host of voices upholding that it is patterns of information, not matter and energy, that constitute the cornerstones of reality. In this paper, we introduce the use of knowledge management tools for the purpose of analysing this topic.

  2. Galileo In-Situ Dust Measurements and the Physics of Jupiter's Gossamer Rings

    NASA Astrophysics Data System (ADS)

    Krueger, H.; Hamilton, D. P.; Moissl, R.; Gruen, E.

    2007-12-01

    During its late orbital mission about Jupiter, the Galileo spacecraft flew twice through the giant planet's gossamer ring system. The dusty ring material is produced when interplanetary impactors collide with embedded moonlets. Optical images imply that the rings are constrained both horizontally and vertically by the orbits of the moons Amalthea and Thebe with the exception of a faint outward protrusion called the Thebe Extension. During the ring passages, the Galileo impact-ionization dust detector counted a few thousand impacts but only about 100 complete data sets of dust impacts (i.e. impact time, impact speed, mass, impact direction, etc.) were successfully transmitted to Earth. The instrument verified the outward extension of the gossamer ring beyond Thebe's orbit and measured a major reduction in particle ring material interior to Thebe's orbit. The existence of this partially evacuated gap in ring material is also indirectly confirmed by Galileo in-situ energetic particle measurements (Norbert Krupp, priv. comm.). Detected particle sizes range from about 0.2 to 4 micron, extending the size distribution by an order of magnitude towards smaller particles than previously derived from optical imaging (Showalter et al., Icarus 2007). The grain size distribution increases towards smaller grains, showing a much higher proportion of small particles in the Amalthea gossamer ring than in the Thebe ring and the Thebe Extension. Our analysis shows that particles contributing most to the optical cross-section are about 4 micron in radius, in agreement with imaging results. Finally, Galileo also detected some micron and sub-micron grains on highly inclined orbits with inclinations up to 20 degrees. Recent modelling (Hamilton & Krueger, Nature, submitted) shows that time variable electromagnetic effects can account for all of these surprising results. In particular, when the ring particles travel through Jupiter's shadow, dust grain electric charges vary systematically

  3. Interrelationships between information and energy using knowledge management tools

    NASA Astrophysics Data System (ADS)

    Lizcano, D.; Martínez, A. María

    2014-10-01

    Edward Fredkin was an enthusiastic advocate of information-based theoretical physics, who, in the early 1980s, proposed a new theory of physics based on the idea that the universe is ultimately composed of software. According to Fredkin, reality should be considered as being composed not of particles, matter and forces or energy but of bits of data or information modified according to computational rules. Fredkin went on to demonstrate that, while energy is necessary for storing and retrieving information, it can be arbitrarily reduced in order to carry out any particular instance of information processing, and this operation does not have a lower bound. This implies that it is information rather than matter or energy that should be considered at the ultimate fundamental constituent of reality. This possibility had already been suggested by other scientists. Norbert Wiener heralded a fundamental shift from energy to information and suggested that the universe was founded essentially on the transformation of information, not energy. However, Konrad Zuse was the first, back in 1967, to defend the idea that a digital computer is computing the universe. Richard P. Feynman showed this possibility in a similar light in his reflections on how information related to matter and energy. Other pioneering research on the theory of digital physics was published by Kantor in 1977 and more recently by Stephen Wolfram in 2002, who thereby joined the host of voices upholding that it is patterns of information, not matter and energy, that constitute the cornerstones of reality. In this paper, we introduce the use of knowledge management tools for the purpose of analysing this topic.

  4. Water security and societal impacts of tropical cyclones in northwestern Mexico, 1970-2010

    NASA Astrophysics Data System (ADS)

    Scott, C. A.; Farfan, L.

    2012-12-01

    Mexico.Norbert Impacts in Alamos, Sonora, 12 Oct. 2008

  5. Signal processing with neural networks: throwing off the yoke of linearity

    NASA Astrophysics Data System (ADS)

    Hecht-Nielsen, Robert

    1991-11-01

    During the 1930s and 1940s Norbert Wiener and others invented the core concepts of linear signal processing. These ideas quickly became popular and played a significant role in the Allies' victory in World War II. During and after the war, linear signal processing theory was greatly expanded and began to take on the character of an imposing monolith. By the mid- 1940s, Wiener (and others, such as Dennis Gabor) came to recognize that linear signal processing theory, while interesting and very useful, was only a piece of a much larger picture. In 1946 and 1958 Gabor and Wiener, respectively, attempted to address the whole picture. While they were not completely successful, they did implicitly set an agenda for a more general approach to signal processing. Although a few others have, from time to time, addressed this agenda; in terms of the signal processing community as a whole it still remains lost in the shadow of the ever-growing monolith of linear signal processing theory. The thesis of this paper is that it is now time to get on with the Wiener and Gabor agenda. It is time to make general signal processing the mainstream focus of the subject. It is argued here that the best way to do this is to abandon the transfer function/Fourier analysis/z-transform approach of the current linear signal processing regime and replace it with a much more natural intellectual framework for general signal processing--the framework offered by neurocomputing. A potential benefit of this refocusing of the field is that the detailed engineering might soon be left to machines, while human technologists will be able to concentrate on the art of signal sculpting.

  6. On small things in water moving around: Purcell's contributions to biology

    NASA Astrophysics Data System (ADS)

    Berg, Howard

    2012-02-01

    I went to see Purcell after finishing my course work for the Ph.D. (1961) to ask whether I might join his group. ``But I don't have any graduate students,`` he said. ``Why is that?'' I asked. ``I can't think of anything to do,'' he replied. That was a wipe out. After I had finished my Ph.D. with Ramsey on the hydrogen maser (1964), Ed and I came up with an idea that led to work on sedimentation field-flow fractionation (PNAS 1967). We had hoped this method would be useful for biology, but problems of adsorption of proteins to surfaces stood in the way. Then I moved over to the biology department and got interested in the motile behavior of bacteria (1968). Here was a subject that I thought Ed would really enjoy. There were wonderful movies made by Norbert Pfennig of experiments done by Theodor Engelmann in the 1880's. We found a 16-mm projector and looked at these movies on Ed's office wall. Ed's first comment proved seminal, ''How can such a small cell swim in a straight line?'' We thought about how cells count molecules in their environment and wrote ``Physics of chemoreception,'' (Biophys. J.,1977). In the meantime, Ed gave a memorable lecture at Viki Weisskopf's retirement symposium, his classic ``Life at low Reynolds number'' (Am. J. Phys. 1977). Ed really wanted to understand what it would be like to swim like a bacterium! He wasn't very interested in what the literature had to say about such a problem, he wanted to think it through for himself. My role was straight man. I very much enjoyed the ride.

  7. Radio Telescopes Reveal Youngest Stellar Corpse

    NASA Astrophysics Data System (ADS)

    2004-06-01

    Astronomers using a global combination of radio telescopes to study a stellar explosion some 30 million light-years from Earth have likely discovered either the youngest black hole or the youngest neutron star known in the Universe. Their discovery also marks the first time that a black hole or neutron star has been found associated with a supernova that has been seen to explode since the invention of the telescope nearly 400 years ago. M51 An artist's impression of Supernova 1986J. The newly discovered nebula around the black hole or neutron star in the center is shown in blue, and is in the center of the expanding, fragmented shell of material thrown off in the supernova explosion, which is shown in red. CREDIT: Norbert Bartel and Michael F. Bietenholz, York University; Artist: G. Arguner (Click on image for larger version) Image Files Artist's Conception (above image, 836K) Galaxy and Supernova (47K) A VLA image (left) of the galaxy NGC 891, showing the bright supernova explosion below the galaxy's center. At right, a closer view of the supernova, made with a global array of radio telescopes. CREDIT: Miguel A. Perez-Torres, Antxon Alberdi and Lucas Lara, Instituto de Astrofisica de Andalucia - CSIC, Spain, Jon Marcaide and Jose C. Guirado, Universidad de Valencia, Spain Franco Mantovani, IRA-CNR, Italy, Eduardo Ros, MPIfR, Germany, and Kurt W. Weiler, Naval Research Laboratory, USA Multi-Frequency Closeup View (201K) Blue and white area shows the nebula surrounding the black hole or neutron star lurking in the center of the supernova. This nebula is apparent at a higher radio frequency (15 GHz). The red and also the contours show the distorted, expanding shell of material thrown off in the supernova explosion. This shell is seen at a lower radio frequency (5 GHz). CREDIT: Michael F. Bietenholz and Norbert Bartel, York University, Michael Rupen, NRAO, NRAO/AUI/NSF A supernova is the explosion of a massive star after it exhausts its supply of nuclear fuel and

  8. Cato Guldberg and Peter Waage, the history of the Law of Mass Action, and its relevance to clinical pharmacology.

    PubMed

    Ferner, Robin E; Aronson, Jeffrey K

    2016-01-01

    We have traced the historical link between the Law of Mass Action and clinical pharmacology. The Law evolved from the work of the French chemist Claude Louis Berthollet, was first formulated by Cato Guldberg and Peter Waage in 1864 and later clarified by the Dutch chemist Jacobus van 't Hoff in 1877. It has profoundly influenced our qualitative and quantitative understanding of a number of physiological and pharmacological phenomena. According to the Law of Mass Action, the velocity of a chemical reaction depends on the concentrations of the reactants. At equilibrium the concentrations of the chemicals involved bear a constant relation to each other, described by the equilibrium constant, K. The Law of Mass Action is relevant to various physiological and pharmacological concepts, including concentration-effect curves, dose-response curves, and ligand-receptor binding curves, all of which are important in describing the pharmacological actions of medications, the Langmuir adsorption isotherm, which describes the binding of medications to proteins, activation curves for transmembrane ion transport, enzyme inhibition and the Henderson-Hasselbalch equation, which describes the relation between pH, as a measure of acidity and the concentrations of the contributory acids and bases. Guldberg and Waage recognized the importance of dynamic equilibrium, while others failed to do so. Their ideas, over 150 years old, are embedded in and still relevant to clinical pharmacology. Here we explain the ideas and in a subsequent paper show how they are relevant to understanding adverse drug reactions. PMID:26174880

  9. The mitochondrial permeability transition pore in AD 2016: An update.

    PubMed

    Biasutto, Lucia; Azzolini, Michele; Szabò, Ildikò; Zoratti, Mario

    2016-10-01

    Over the past 30years the mitochondrial permeability transition - the permeabilization of the inner mitochondrial membrane due to the opening of a wide pore - has progressed from being considered a curious artifact induced in isolated mitochondria by Ca(2+) and phosphate to a key cell-death-inducing process in several major pathologies. Its relevance is by now universally acknowledged and a pharmacology targeting the phenomenon is being developed. The molecular nature of the pore remains to this day uncertain, but progress has recently been made with the identification of the FOF1 ATP synthase as the probable proteic substrate. Researchers sharing this conviction are however divided into two camps: these believing that only the ATP synthase dimers or oligomers can form the pore, presumably in the contact region between monomers, and those who consider that the ring-forming c subunits in the FO sector actually constitute the walls of the pore. The latest development is the emergence of a new candidate: Spastic Paraplegia 7 (SPG7), a mitochondrial AAA-type membrane protease which forms a 6-stave barrel. This review summarizes recent developments of research on the pathophysiological relevance and on the molecular nature of the mitochondrial permeability transition pore. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26902508

  10. Color consilience: color through the lens of art practice, history, philosophy, and neuroscience.

    PubMed

    Conway, Bevil R

    2012-03-01

    Paintings can be interpreted as the product of the complex neural machinery that translates physical light signals into behavior, experience, and emotion. The brain mechanisms responsible for vision and perception have been sculpted during evolution and further modified by cultural exposure and development. By closely examining artists' paintings and practices, we can discover hints to how the brain works, and achieve insight into the discoveries and inventions of artists and their impact on culture. Here, I focus on an integral aspect of color, color contrast, which poses a challenge for artists: a mark situated on an otherwise blank canvas will appear a different color in the context of the finished painting. How do artists account for this change in color during the production of a painting? In the broader context of neural and philosophical considerations of color, I discuss the practices of three modern masters, Henri Matisse, Paul Cézanne, and Claude Monet, and suggest that the strategies they developed not only capitalized on the neural mechanisms of color, but also influenced the trajectory of western art history. PMID:22429199

  11. Monet's painting under the microscope.

    PubMed

    Dredge, Paula; Wuhrer, Richard; Phillips, Matthew R

    2003-04-01

    An oil painting by Claude Monet, Port-Goulphar, Belle-Ile 1887 (collection of the Art Gallery of New South Wales), was examined to determine both the identity of the pigments used by the artist in this painting and his technique of mixing colors and laying paint on the canvas. The extremely complex construction of the painting was revealed by optical microscopy, scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDS), and X-ray mapping (XRM) analysis of cross sections of paint flakes excised from damaged regions of Port-Goulphar, Belle-Ile. Nine different pigments were found on the painting. Many of the identified colors were modern pigments that became available only late in the 19th century as a result of scientific advances in pigment chemistry. Although similar colors were available in a natural mineral form, they lacked the vivid color of their manufactured counterparts. The use of these new synthetic metallic oxide colors by Monet accounts for the brilliance of his paintings. In addition, a separation between successive paint layers was observed in some areas of paint chip cross sections, indicating that oil-based paint was applied to paint that had dried, and consequently, Port-Goulphar, Belle-Ile was painted over a long period of time. This observation is contrary to the general perception of Monet's technique of painting freely and quickly. PMID:12639239

  12. Monet's Painting under the Microscope

    NASA Astrophysics Data System (ADS)

    Dredge, Paula; Wuhrer, Richard; Phillips, Matthew R.

    2003-04-01

    An oil painting by Claude Monet, Port-Goulphar, Belle-Ile 1887 (collection of the Art Gallery of New South Wales), was examined to determine both the identity of the pigments used by the artist in this painting and his technique of mixing colors and laying paint on the canvas. The extremely complex construction of the painting was revealed by optical microscopy, scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDS), and X-ray mapping (XRM) analysis of cross sections of paint flakes excised from damaged regions of Port-Goulphar, Belle-Ile. Nine different pigments were found on the painting. Many of the identified colors were modern pigments that became available only late in the 19th century as a result of scientific advances in pigment chemistry. Although similar colors were available in a natural mineral form, they lacked the vivid color of their manufactured counterparts. The use of these new synthetic metallic oxide colors by Monet accounts for the brilliance of his paintings. In addition, a separation between successive paint layers was observed in some areas of paint chip cross sections, indicating that oil-based paint was applied to paint that had dried, and consequently, Port-Goulphar, Belle-Ile was painted over a long period of time. This observation is contrary to the general perception of Monet's technique of painting freely and quickly.

  13. [Influence of disease on Matisse and Monet painting].

    PubMed

    Castillo-Ojugas, Antonio

    2003-01-01

    Henri Matisse (1869-1954) "Fauvisme", radically changed as for 1941, when he endured a severe surgery due to intestinal cancer. The resulting wound got necrosis, leading to a deficit at his abdominal muscles that impeached him to remain standing and paint. Sitting on his wheelchair, he started to cut out pieces of papers with which we created artistic collages. He died in 1954, aged 84, almost 13 years after his surgery. Claude Monet (1840-1926). After a journey to Venice in 1908, when he was 68 years old, cataracts were detected in Monet's both eyes, leading to the loss of his sight on his left eye and to an abnormal perception of colours on his right one. These alterations can be detected at his pieces of work. The surgery on his right eye en 1923, evoluted to a rare complication, know as "Xantopsia", that is, yellow-coloured sight, which was partially corrected through "Zeiss" linses. He died on lung cancer on 5th December 1926, aged 86. PMID:15147054

  14. The renaissance of Peiresc: Aubin-Louis Millin and the postrevolutionary republic of letters.

    PubMed

    Adkins, G Matthew

    2008-12-01

    This essay argues for the emergence of a cultural and epistemological divide between amateur savants and members of the Royal Academy of the Sciences in late Old Regime and revolutionary France and suggests that the amateur ideal rose in significance even as intellectual activity came to be increasingly centralized in the postrevolutionary era. At the crux of the tensions between the amateur ideal and the professionalizing reality in the immediate postrevolutionary period stood Aubin-Louis Millin and his journal, the Magasin Encyclopédique. The essay examines, in particular, the revival in the pages of the Magasin Encyclopédique of interest in Nicolas-Claude Fabri de Peiresc, the seventeenth-century icon of an amateur ideal in which investigations in the natural sciences and scholarship were private, decentralized, often provincial activities. Although the sciences in the revolutionary and Napoleonic eras were often perceived as forward looking and dismissive of the past, this essay finds that a sentimental and nostalgic attachment to the past-to a myth of Peiresc-continued to play an important role in the identity of postrevolutionary men of letters. PMID:19334517

  15. Milestones in the history of diabetes mellitus: The main contributors

    PubMed Central

    Karamanou, Marianna; Protogerou, Athanase; Tsoucalas, Gregory; Androutsos, George; Poulakou-Rebelakou, Effie

    2016-01-01

    Diabetes mellitus is a group of metabolic diseases involving carbohydrate, lipid, and protein metabolism. It is characterized by persistent hyperglycemia which results from defects in insulin secretion, or action or both. Diabetes mellitus has been known since antiquity. Descriptions have been found in the Egyptian papyri, in ancient Indian and Chinese medical literature, as well as, in the work of ancient Greek and Arab physicians. In the 2nd century AD Aretaeus of Cappadocia provided the first accurate description of diabetes, coining the term diabetes, while in 17th century Thomas Willis added the term mellitus to the disease, in an attempt to describe the extremely sweet taste of the urine. The important work of the 19th century French physiologist Claude Bernard, on the glycogenic action of the liver, paved the way for further progress in the study of the disease. In 1889, Oskar Minkowski and Joseph von Mering performed their famous experiment of removing the pancreas from a dog and producing severe and fatal diabetes. In 1921, Frederick Banting and Charles Best extended Minkowski’s and Mering’s experiment. They isolated insulin from pancreatic islets and administrated to patients suffering from type 1 diabetes, saving thus the lives of millions and inaugurating a new era in diabetes treatment. PMID:26788261

  16. Evolution of concepts of stress.

    PubMed

    Goldstein, David S; Kopin, Irwin J

    2007-06-01

    This essay describes the evolution of stress as a medical scientific idea. Claude Bernard, Walter B. Cannon and Hans Selye provided key founding concepts for the current view. Bernard introduced the idea of the internal environment bathing cells - the milieu intérieur - maintained by continual compensatory changes of bodily functions. Cannon coined the word, "homeostasis," referring to a set of acceptable ranges of values for internal variables. Cannon taught that threats to homeostasis evoke activation of the sympathoadrenal system as a functional unit. Selye defined stress as a state characterized by a uniform response pattern, regardless of the particular stressor, that could lead to long-term pathologic changes. "Allostasis" was introduced as a concept in recognition that there is no single ideal set of steady-state conditions in life; instead, setpoints and other response criteria change continuously. Stress is now viewed neither as a perturbation nor a stereotyped response pattern but as a condition characterized by a perceived discrepancy between information about a monitored variable and criteria for eliciting patterned effector responses. Different stressors elicit different patterns of activation of the sympathetic nervous, adrenomedullary hormonal, hypothalamic-pituitary-adrenocortical and other effectors, closing negative feedback loops. This systems concept of stress yields predictions that observation or experimentation can test and that are applicable to normal physiology and to a variety of acute and chronic disorders. PMID:17514579

  17. STS-103 Mission Specialist Grunsfeld and his family DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist John M. Grunsfeld (Ph.D.), with his wife, Carol, and their children, smiles for the camera on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  18. STS-103 Mission Specialist Foale and his family DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist C. Michael Foale (Ph.D.) holds one of his children on the runway at Patrick Air Force Base in Cocoa Beach, Fla., as his wife, Rhonda, looks on. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists Steven L. Smith, John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  19. STS-103 crew members and their families pose for a portrait before DEPARTing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew pose for a group portrait with their families and loved ones on the runway at Patrick Air Force Base in Cocoa Beach, Fla. They are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. From left to right, the crew members are Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland, Jean-Frangois Clervoy of France, and Steven L. Smith; Pilot Scott J. Kelly; and Commander Curtis L. Brown Jr. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  20. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, the STS-103 crew look over equipment to be used during their mission. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  1. [On the evolution of scientific thought].

    PubMed

    de Micheli, Alfredo; Iturralde Torres, Pedro

    2015-01-01

    The Nominalists of the XIV century, precursors of modern science, thought that science's object was not the general, vague and indeterminate but the particular, which is real and can be known directly. About the middle of the XVII Century the bases of the modern science became established thanks to a revolution fomented essentially by Galileo, Bacon and Descartes. During the XVIII Century, parallel to the development of the great current of English Empiricism, a movement of scientific renewal also arose in continental Europe following the discipline of the Dutch Physicians and of Boerhaave. In the XIX Century, Claude Bernard dominated the scientific medicine but his rigorous determinism impeded him from taking into account the immense and unforeseeable field of the random. Nowadays, we approach natural science and medicine, from particular groups of facts; that is, from the responses of Nature to specific questions, but not from the general laws. Furthermore, in recent epistemology, the concept that experimental data are not pure facts, but rather, facts interpreted within a hermeneutical context has been established. Finally a general tendency to retrieve philosophical questions concerning the understanding of essence and existence can frequently be seen in scientific inquiry. In the light of the evolution of medical thought, it is possible to establish the position of scientific medicine within the movement of ideas dominating in our time. PMID:26296626

  2. Web-based Teaching Radio Interferometer for Africa

    NASA Astrophysics Data System (ADS)

    Carignan, Claude

    2015-08-01

    Practical training for the future use of the African VLBI Network (AVN) or any VLBI experiment starts by understanding the basic principles of radio observations and radio interferometry. The aim of this project is to build a basic interferometer that could be used remotely via a web interface from any country on the African continent. This should turn out as a much less expensive and much more efficient way to train AVN researchers from SKA partner countries to the principles of radio astronomy and to interferometric data analysis. The idea is based on the very successful EUHOU (European Hands-On Universe) already very successful in Europe. The former EUHOU manager, Dr Yannick Liebert, arrived for a 3 years postdoc with Prof Claude Carignan at the University of Cape Town to implement the same project on the African continent (AHI: African Hands-on Interferometry). Besides the use of AHI for the AVN researchers, this web-based system could be used be any undergraduate program on radio astronomical techniques across the African continent as the EUHOU is used all across Europe.

  3. Glycogen branches out: new perspectives on the role of glycogen metabolism in the integration of metabolic pathways.

    PubMed

    Greenberg, Cynthia C; Jurczak, Michael J; Danos, Arpad M; Brady, Matthew J

    2006-07-01

    Glycogen is the storage form of carbohydrate for virtually every organism from yeast to primates. Most mammalian tissues store glucose as glycogen, with the major depots located in muscle and liver. The French physiologist Claude Bernard first identified a starch-like substance in liver and muscle and coined the term glycogen, or "sugar former," in the 1850s. During the 150 years since its identification, researchers in the field of glycogen metabolism have made numerous discoveries that are now recognized as significant milestones in biochemistry and cell signaling. Even so, more questions remain, and studies continue to demonstrate the complexity of the regulation of glycogen metabolism. Under classical definitions, the functions of glycogen seem clear: muscle glycogen is degraded to generate ATP during increased energy demand, whereas hepatic glycogen is broken down for release of glucose into the bloodstream to supply other tissues. However, recent findings demonstrate that the roles of glycogen metabolism in energy sensing, integration of metabolic pathways, and coordination of cellular responses to hormonal stimuli are far more complex. PMID:16478770

  4. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test, STS-103 Commander Curtis L. Brown Jr. (left) and Pilot Scott J. Kelly look at a replacement computer for the Hubble Space Telescope. The payload hardware is in the Payload Hazardous Servicing Facility. Other members of the crew are Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with the new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  5. Cycle design for the ISABELLE helium refrigerator

    SciTech Connect

    Brown, D.P.; Schlafke, A.P.; Wu, K.C.; Moore, R.W.

    1981-01-01

    The superconducting magnets for the ISABELLE storage ring/accelerator are designed to be operated at 3.8/sup 0/K using a forced-flow supercritical helium cooling system. The ISABELLE refrigerator has been designed subject to these special requirements. The design output is 13.65 KW of refrigeration below 4.2/sup 0/K (for cooling the magnet and distribution system), 55 KW at 55/sup 0/K (to cool heat shields for the whole system) and 100 g/s of liquefaction (for magnet power leads cooling). The system incorporates a subcooler section that produces liquid helium at 5.3 atm and 2.6 K and circulates it through the loads, and a Claude-type main refrigerator section. The main refrigerator section has five stages of cooling, with four of them below liquid nitrogen temperature. Liquid nitrogen precooling is not used. With 60% isothermal compressors the efficiency of the refrigerator system will be about 26% of Carnot.

  6. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test, members of the STS-103 crew check out new Multi-Layer Insulation (MLI) for the Hubble Space Telescope. The payload hardware is in the Payload Hazardous Servicing Facility. From left are Mission Specialists Claude Nicollier of Switzerland, Steven L. Smith, C. Michael Foale (Ph.D.), and John M. Grunsfeld (Ph.D.). Other members of the crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialist Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with the MLI. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  7. [Stress and allostasis: problems, outlooks and relationships].

    PubMed

    Kupriianov, R V; Zhdanov, R I

    2014-01-01

    Concepts of stress and allostasis are discussed in the paper in their interrelation and interpenetration. General adaptation syndrome is considered in the historical aspect of Claude Bernard's, William Cannon's and Hans Selye's contributions to the field, and from the standpoint of an interdisciplinary approach. Key challenges and contradictions of the stress concept are disclosed and discussed. First, the terminology ones, since this term might be understood as stress response, stressor, state of the organism and even the consequences of stress itself. Second, it is ambivalent and contradictory nature of the stress response. From the perception of stress as a reaction to the strong negative impact of environment, researchers became to divide stress onto two types: distress as a non-specific basis of disease, and eustress as a favorable factor that extends the adaptability of human organism. The third problem is connected to the interdisciplinary nature of the stress response, the effects of which being manifested in, at least, four areas: physiology, behavior, subjective experience, and cognitive functions. Particularily, physiologists are very often ignored of a role of cognitive factors in their stress research. The authors in terms of the allostasis theory, more complex adaptation process than homeostasis, resolve contradictories of stress conception observed. The paper proposes a model of allostatic states to describe distress and eustress phenomena. PMID:25707255

  8. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, STS-103 Mission Specialist Steven L. Smith (right) and other members of the crew look over new Multi-Layer Insulation (MLI) intended for the Hubble Space Telescope. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with the MLI. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  9. Laws, leaders, and legends of the modern National Library of Medicine

    PubMed Central

    Smith, Kent A.

    2008-01-01

    Purpose: The paper is an expanded version of the 2007 Joseph Leiter National Library of Medicine (NLM)/Medical Library Association Lecture presented at MLA ‘07, the Medical Library Association annual meeting in Philadelphia in May 2007. It presents an historical accounting of four major pieces of legislation, beginning with the NLM Act of 1956 up through the creation of the National Center for Biotechnology Information. Brief Description: The transition from the United States Armed Forces Medical Library to the United States National Library of Medicine in 1956 was a major turning point in NLM's history, scope, and direction. The succeeding landmark legislative achievements—namely, the 1965 Medical Library Assistance Act, the 1968 Joint Resolution forming the Lister Hill National Center for Biomedical Communications, and the 1988 authorization for the National Center for Biotechnology Information— transformed the library into a major biomedical communications institution and a leader and supporter of an effective national network of libraries of medicine. The leaders of the library and its major advocates—including Dr. Michael DeBakey, Senator Lister Hill, and Senator Claude Pepper—together contributed to the creation of the modern NLM. PMID:18379667

  10. Epidemiology: second-rate science?

    PubMed

    Parascandola, M

    1998-01-01

    In recent years epidemiology has come under increasing criticism in regulatory and public arenas for being "unscientific." The tobacco industry has taken advantage of this, insisting for decades that evidence linking cigarettes and lung cancer falls short of proof. Moreover, many epidemiologists remain unduly skeptical and self-conscious about the status of their own causal claims. This situation persists in part because of a widespread belief that only the laboratory can provide evidence sufficient for scientific proof. Adherents of this view erroneously believe that there is no element of uncertainty or inductive inference in the "direct observation" of the laboratory researcher and that epidemiology provides mere "circumstantial" evidence. The historical roots of this attitude can be traced to philosopher John Stuart Mill and physiologist Claude Bernard and their influence on modern experimental thinking. The author uses the debate over cigarettes and lung cancer to examine ideas of proof in medical science and public health, concluding that inductive inference from a limited sample to a larger population is an element in all empirical science. PMID:9672568

  11. Linking Nuclear Reactions and Nuclear Structure on the Way to the Drip Line

    NASA Astrophysics Data System (ADS)

    Dickhoff, Willem

    2012-10-01

    The present understanding of the role of short- and long-range physics in determining proton properties near the Fermi energy for stable closed-shell nuclei has relied on data from the (e,e'p) reaction. Hadronic tools to extract such spectroscopic information have been hampered by the lack of a consistent reaction description that provides unambiguous and undisputed results. The dispersive optical model (DOM), originally conceived by Claude Mahaux, provides a unified description of both elastic nucleon scattering and structure information related to single-particle properties below the Fermi energy. The DOM provides the starting point to provide a framework in which nuclear reactions and structure data can be analyzed consistently to provide unambiguous spectroscopic information including its asymmetry dependence. Recent extensions of this approach include the treatment of non-locality to describe experimental data like the nuclear charge density based on information of the spectral density below the Fermi energy, the application of the DOM ingredients to the description of transfer reactions, a comparison of the microscopic content of the nucleon self-energy based on Faddeev-RPA calculations emphasizing long-range correlations with DOM potentials, and a study of the relation between a self-energy which includes the effect of short-range correlations with DOM potentials. The most recent Dom implementation currently in progress abandons the constraint of local potentials completely to allow an accurate description of various properties of the nuclear ground state.

  12. The French Ambassador in Firing Room to watch launch.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Firing Room (left to right) Joseph Rothenberg, associate administrator, Office of Space Flight; JoAnn Morgan, associate director for Advanced Development and Shuttle Upgrades; and Madam de L'Estang and Francois Bujon de L'Estang, ambassador of France, wait for the launch of STS-103. One of the STS-103 crew, Mission Specialist Jean-Francois Clervoy, is from France, and a member of the European Space Agency (ESA). Other crew members are Commander Curtis L. Brown Jr. , Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Claude Nicollier of Switzerland (also with ESA). The mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 19 at 7:50 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  13. The French Ambassador in Firing Room to watch launch.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On hand in the Firing Room to watch the launch of STS-103 are (left to right) Joseph Rothenberg, associate administrator, Office of Space Flight; JoAnn Morgan, associate director for Advanced Development and Shuttle Upgrades; and Francois Bujon de L'Estang, ambassador of France. Behind the ambassador is his wife, Madam de L'Estang. One of the STS-103 crew, Mission Specialist Jean-Francois Clervoy, is from France, and a member of the European Space Agency (ESA). Other crew members are Commander Curtis L. Brown Jr. , Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Claude Nicollier of Switzerland (also with ESA). The mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 19 at 7:50 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST

  14. The history of cardiac catheterization.

    PubMed

    Bourassa, Martial G

    2005-10-01

    The evolution of cardiac catheterization has occurred over at least four centuries. One of the first major steps was the description of the circulation of the blood by William Harvey in 1628. The next milestone was the measurement of arterial pressure by Stephen Hales, one century later. However, the 19th century represented the golden age of cardiovascular physiology, highlighted by the achievements of Carl Ludwig, Etienne-Jules Marey and Claude Bernard, among others. Human cardiac catheterization developed during the 20th century. The first right heart catheterization in a human was performed by Werner Forssmann on himself in 1929. Diagnostic cardiac catheterization was introduced by André Cournand and Dickinson Richards in the early 1940s, and selective coronary angiography was described by Mason Sones in the early 1960s. More recently, with the advent of catheter-based interventions, pioneered by Andreas Gruentzig in the late 1970s, there has been considerable progress in the refinement and expansion of these techniques. Currently, the Sones technique is used only infrequently, and coronary angiography and percutaneous coronary intervention rely mainly on percutaneous femoral and percutaneous radial artery approaches. On the occasion of the 50th anniversary of the Montreal Heart Institute, it seems appropriate to highlight the contribution of this institution in these two areas. PMID:16234881

  15. Vascular access: an historical perspective from Sir William Harvey to the 1956 Nobel prize to André F. Cournand, Werner Forssmann, and Dickinson W. Richards.

    PubMed

    Sette, Piersandro; Dorizzi, Romolo M; Azzini, Anna M

    2012-01-01

    Sir William Harvey (1578-1657), who had many precursors, discovered blood circulation in 1628 after a significant number of anatomic dissection of cadavers; his studies were continued by Sir Christopher Wren and Daniel Johann Major. The first central vein catheterization was performed on a horse by Stephen Hales, an English Vicar. In 1844, a century later, the French biologist Claude Bernard attempted the first carotid artery cannulation and repeated the procedure in the jugular vein, again on a horse. He was first to report the complications now well known to be associated with this maneuver. In 1929 Werner Forssmann tried cardiac catheterization on himself, but could not investigate the procedure further since his findings were rejected and ridiculed by colleagues. His work was continued by André Frédéric Cournand and Dickinson Woodruff Richards Jr in the United States. In 1956 the three physicians shared the Nobel Prize for Medicine for their studies on vascular and cardiac systems. The genius and the perseverance of the three physicians paved the way towards peripheral and central catheter vein placement, one of the most frequently performed maneuvers in hospitals. Its history still remains unknown to most and deserves a short description. PMID:21983826

  16. STS-46 post flight press conference

    NASA Astrophysics Data System (ADS)

    1992-08-01

    At a post flight press conference, the flight crew of the STS-46 mission (Cmdr. Loren Shriver, Pilot Andrew Allen, Mission Specialists Claude Nicollier (European Space Agency (ESA)), Marsha Ivins (Flight Engineer), Jeff Hoffman (Payload Commander), Franklin Chang-Dias, and Payload Specialist Franco Malerba (Italian Space Agency (ISA))) discussed their roles in and presented video footage, slides and still photographs of the different aspects of their mission. The primary objectives of the mission were the deployment of ESA's European Retrievable Carrier (EURECA) satellite and the joint NASA/ISA deployment and testing of the Tethered Satellite System (TSS). Secondary objectives included the IMAX Camera, the Limited Duration Space Environment Candidate Materials Exposure (LDVE), and the Pituitary Growth Hormone Cell Function (PHCF) experiments. Video footage of the EURECA and TSS deployment procedures are shown. Earth views were extensive and included Javanese volcanoes, Amazon basin forest ground fires, southern Mexico, southern Bolivian volcanoes, south-west Sudan and the Sahara Desert, and Melville Island, Australia. Questions from reporters and journalists from Johnson Space Center and Kennedy Space Center were discussed.

  17. Cryogenics for the MuCool Test Area (MTA)

    SciTech Connect

    Darve, Christine; Norris, Barry; Pei, Liu-Jin; /Fermilab

    2005-09-01

    MuCool Test Area (MTA) is a complex of buildings at Fermi National Accelerator Laboratory, which are dedicated to operate components of a cooling cell to be used for Muon Collider and Neutrino Factory R&D. The long-term goal of this facility is to test ionization cooling principles by operating a 25-liter liquid hydrogen (LH{sub 2}) absorber embedded in a 5 Tesla superconducting solenoid magnet. The MTA solenoid magnet will be used with RF cavities exposed to a high intensity beam. Cryogens used at the MTA include LHe, LN{sub 2} and LH{sub 2}. The latter dictates stringent system design for hazardous locations. The cryogenic plant is a modified Tevatron refrigerator based on the Claude cycle. The implementation of an in-house refrigerator system and two 300 kilowatt screw compressors is under development. The helium refrigeration capacity is 500 W at 14 K. In addition the MTA solenoid magnet will be batch-filled with LHe every 2 days using the same cryo-plant. This paper reviews cryogenic systems used to support the Muon Collider and Neutrino Factory R&D programs and emphasizes the feasibility of handling cryogenic equipment at MTA in a safe manner.

  18. The VDAC channel: Molecular basis for selectivity.

    PubMed

    Colombini, Marco

    2016-10-01

    The voltage dependent anion-selective channel, VDAC, is the major permeability pathway by which molecules and ion cross the mitochondrial outer membrane. This pathway has evolved to optimize the flow of these substances and to control this flow by a gating process that is influenced by a variety of factors including transmembrane voltage. The permeation pathway formed through the membrane by VDAC is complex. Small ion flow is primarily influenced by the charged surface of the inner walls of the channel. Channel closure changes this landscape resulting in a change from a channel that favors anions to one that favors cations. Molecular ions interact more intimately with the inner walls of the channel and are selected by their 3-dimensional structure, not merely by their size and charge. Molecular ions typically found in cells are greatly favored over those that are not. For these larger structures the channel may form a low-energy translocation path that complements the structure of the permeant. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26826035

  19. Active space debris removal by using laser propulsion

    NASA Astrophysics Data System (ADS)

    Rezunkov, Yu. A.

    2013-03-01

    At present, a few projects on the space debris removal by using highpower lasers are developed. One of the established projects is the ORION proposed by Claude Phipps from Photonics Associates Company and supported by NASA (USA) [1]. But the technical feasibility of the concept is limited by sizes of the debris objects (from 1 to 10 cm) because of a small thrust impulse generated at the laser ablation of the debris materials. At the same time, the removal of rocket upper stages and satellites, which have reached the end of their lives, has been carried out only in a very small number of cases and most of them remain on the Low Earth Orbits (LEO). To reduce the amount of these large-size objects, designing of space systems allowing deorbiting upper rocket stages and removing large-size satellite remnants from economically and scientifically useful orbits to disposal ones is considered. The suggested system is based on high-power laser propulsion. Laser-Orbital Transfer Vehicle (LOTV) with the developed aerospace laser propulsion engine is considered as applied to the problem of mitigation of man-made large-size space debris in LEO.

  20. The latest developments and outlook for hydrogen liquefaction technology

    SciTech Connect

    Ohlig, K.; Decker, L.

    2014-01-29

    Liquefied hydrogen is presently mainly used for space applications and the semiconductor industry. While clean energy applications, for e.g. the automotive sector, currently contribute to this demand with a small share only, their demand may see a significant boost in the next years with the need for large scale liquefaction plants exceeding the current plant sizes by far. Hydrogen liquefaction for small scale plants with a maximum capacity of 3 tons per day (tpd) is accomplished with a Brayton refrigeration cycle using helium as refrigerant. This technology is characterized by low investment costs but lower process efficiency and hence higher operating costs. For larger plants, a hydrogen Claude cycle is used, characterized by higher investment but lower operating costs. However, liquefaction plants meeting the potentially high demand in the clean energy sector will need further optimization with regard to energy efficiency and hence operating costs. The present paper gives an overview of the currently applied technologies, including their thermodynamic and technical background. Areas of improvement are identified to derive process concepts for future large scale hydrogen liquefaction plants meeting the needs of clean energy applications with optimized energy efficiency and hence minimized operating costs. Compared to studies in this field, this paper focuses on application of new technology and innovative concepts which are either readily available or will require short qualification procedures. They will hence allow implementation in plants in the close future.

  1. Functions of mature mammalian astrocytes: a current view.

    PubMed

    Kimelberg, Harold K

    2010-02-01

    Before the roles of normal, mature astrocytes in the mammalian CNS can be discussed, we first need to define these cells. A definition proposed here is that such a class is best defined as consisting of the protoplasmic and fibrous astrocytes of the gray and white matter, respectively, the Bergmann glia of the molecular layer of the cerebellum, and the Muller cells of the retina. It is concluded that the established properties and functions of these mature astrocytes are essential support for neuronal activity, in the sense of Claude Bernard's principle of maintaining "la fixité du milieu intérieur." This milieu would be the extracellular space common to astrocytes and neurons. More specialized roles, such as the recently described "light guides" for retinal Muller cells can also be viewed as support and facilitation. The ECS is also, of course, common to all other neural cells, but here, I limit the discussion to perturbations of the ECS caused only by neuronal activities and the resolution of these perturbations by astrocytes, such as control of increases in extracellular K(+), uptake of excitatory amino acids, and alterations in blood vessel diameter and therefore blood flow. It is also proposed how this fits into the current morphological picture for the protoplasmic astrocytes as having small cell bodies with up to 100,000 process endings that occupy separate territories on which the processes of neighboring astrocytes scarcely intrude. PMID:20236950

  2. A curious experiment: the paradigm switch from observation and speculation to experimentation, in the understanding of neuromuscular function and disease.

    PubMed

    Pearn, John

    2002-08-01

    The four-link chain of the motor unit represents the contemporary end-point of some two millennia of evolving knowledge in neuroscience. The paradigm shift in neuromuscular epistemology occurred in the mid-17th century. In 1666, the newly graduated Dutch doctor, Jan Swammerdam (1637-1680) published his former investigations of dissected nerve-muscle preparations. These experiments comprised the quantum leap from observation and speculation, to that of experimentation in the field of neuroanatomy and neurophysiology. In what he termed 'A Curious Experiment' he also described the phenomenon of intrinsic muscle excitability - "I cannot observe that the muscle in the living animal ever absolutely ceases from all motion". Eighty years later (1752), von Haller demonstrated experimentally that irritability (contractility) was an intrinsic property of all muscular tissue; and distinguished between the sensibility of nerve impulses and the irritability of muscular contraction. This experimental progression from Swammerdam to von Haller culminated in 1850, when Claude Bernard's studies in experimental pharmacology confirmed that muscle was a functional unit, independent of any electrical innervation via its supplying nerve. This account comprises an audit of Swammerdam's work in the perspective of neuromuscular knowledge. PMID:12117487

  3. Gerontologic Biostatistics: The Statistical Challenges of Clinical Research with Older Study Participants

    PubMed Central

    Van Ness, Peter H.; Charpentier, Peter A.; Ip, Edward H.; Leng, Xiaoyan; Murphy, Terrence E.; Tooze, Janet A.; Allore, Heather G.

    2010-01-01

    The medical and personal circumstances of older persons present challenges for designing and analyzing clinical research studies in which they participate. These challenges presented by elderly study samples are not unique but they are sufficiently distinctive to warrant deliberate and systematic attention. Their distinctiveness originates in the multifactorial etiologies of geriatric health syndromes and the multiple morbidities accruing with aging at the end of life. The objective of this article is to identify a set of statistical challenges arising in research with older persons that should be considered conjointly in the practice of clinical research and that should be addressed systematically in the training of biostatisticians intending to work with gerontologists, geriatricians, and older study participants. The statistical challenges include design and analytical strategies for multicomponent interventions, multiple outcomes, state transition models, floor and ceiling effects, missing data, and mixed methods. The methodological and pedagogical themes of this article will be integrated by a description of a proposed subdiscipline of “gerontologic biostatistics” and supported by the introduction of new set of statistical resources for researchers working in this area. These conceptual and methodological resources have been developed in the context of several collaborating Claude D. Pepper Older Americans Independence Centers. PMID:20533963

  4. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, members of the STS-103 crew get instructions on use of rib clamps for the Shield Shell Replacement Fabric (SSRF) task on repair of the Hubble Space Telescope. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  5. Ocean thermal energy conversion: Historical highlights, status, and forecast

    SciTech Connect

    Dugger, G.L.; Avery, W.H.; Francis, E.J.; Richards, D.

    1983-07-01

    In 1881, d'Arsonval conceived the closed-Rankine-cycle ocean thermal energy conversion (OTEC) system in which a working fluid is vaporized by heat exchange with cold water drawn from a 700-1200 m depth. In 1930, Claude demonstrated an open-cycle process in Cuba. Surface water was flash-vaporized at 3 kPa to drive a turbine directly (no secondary working fluid) and then was condensed by direct contact with water drawn from a 700-m depth through a 1.6m-diam, 1.75-km-long cold-water pipe (CWP). From a delta T of 14/sup 0/C his undersized turbine generated 22 kW. In 1956 a French team designed a 3.5-MW (net) open-cycle plant for installation off Abidjan on the Ivory Coast of Africa and demonstrated the necessary CWP deployment. The at-sea demonstrations by Mini-OTEC and OTEC-1 and other recent advances in OTEC technology summarized herein represent great progress. All of the types of plants proposed for the DOE's PON program may be worthy of development; certainly work on a grazing plant is needed. Our estimates indicate that the U.S. goals established by Public Law 96-310 leading to 10 GW of OTEC power and energy product equivalents by 1999 are achievable, provided that adequate federal financial incentives are retained to assure the building of the first few plants.

  6. STS-103 crew pose at 195-foot level of Fixed Service Structure

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the 195-foot level of the Fixed Service Structure on Launch Pad 39B, the STS-103 crew take a break from Terminal Countdown Demonstration Test (TCDT) activities. Standing from left to right are Mission Specialists Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency; Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.) and Steven L. Smith. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  7. Transoral Robotic Surgery in Retrostyloid Parapharyngeal Space Schwannomas

    PubMed Central

    Ansarin, Mohssen; Tagliabue, Marta; Chu, Francesco; Zorzi, Stefano; Proh, Michele; Preda, Lorenzo

    2014-01-01

    Parapharyngeal space (PPS) tumors are very rare, representing about 0.5% of head and neck neoplasms. An external surgical approach is mainly used. Several recent papers show how transoral robotic surgery (TORS) excision could be a prospective tool to remove mainly benign lesions in PPS; no cases of neurogenic tumors from the retrostyloid space treated with TORS have been reported. We present two cases which underwent TORS for schwannomas from the retrostyloid compartment of the parapharyngeal space. Clinical diagnosis of schwannoma was performed by magnetic resonance imaging (MRI). In the first case a 6 cm neurogenic tumor arose from the vagus nerve and in the second case a 5 cm mass from the sympathetic chain was observed. Both cases were treated successfully by the TORS approach using a new “J”-shaped incision through the mucosa and superior pharyngeal constrictor muscle. Left vocal cord palsy and the Claude Bernard Horner syndrome, respectively, were observed as expected postsurgical sequelae. In case 1 the first bite syndrome developed after three months, while no complications were observed in case 2. Both patients regained a normal swallowing function. TORS seems to be a feasible mini-invasive procedure for benign PPS masses including masses in the poststyloid space. PMID:25202464

  8. Sir Michael Foster MD FRS (1836-1907): the rise of the British school of physiology.

    PubMed

    Hawgood, Barbara J

    2008-11-01

    In 1867 William Sharpey (1802-80), Professor of General Anatomy and Physiology at University College, London, appointed Michael Foster to the unique post of Teacher of Practical Physiology; in Britain the study of experimental physiology was dormant. In 1870 Foster accepted a Praelectorship in Physiology at Trinity College, Cambridge, and soon established a school of physiology. He was the first Cambridge Professor of Physiology (1883-1903). Foster, a great teacher, had a remarkable ability to attract talented students and to inspire them to undertake research. He himself took inspiration from the scientific philosophy of Thomas Henry Huxley (1825-95) and of Claude Bernard (1813-78). Foster was active in the foundation of the Physiological Society (1876), and founded and edited the Journal of Physiology (1878). He was interested in the scientific training of medical students and wrote a highly lauded Text Book of Physiology (1877). Physiology became a profession in its own right and British physiologists were in the vanguard of research. PMID:18952994

  9. The latest developments and outlook for hydrogen liquefaction technology

    NASA Astrophysics Data System (ADS)

    Ohlig, K.; Decker, L.

    2014-01-01

    Liquefied hydrogen is presently mainly used for space applications and the semiconductor industry. While clean energy applications, for e.g. the automotive sector, currently contribute to this demand with a small share only, their demand may see a significant boost in the next years with the need for large scale liquefaction plants exceeding the current plant sizes by far. Hydrogen liquefaction for small scale plants with a maximum capacity of 3 tons per day (tpd) is accomplished with a Brayton refrigeration cycle using helium as refrigerant. This technology is characterized by low investment costs but lower process efficiency and hence higher operating costs. For larger plants, a hydrogen Claude cycle is used, characterized by higher investment but lower operating costs. However, liquefaction plants meeting the potentially high demand in the clean energy sector will need further optimization with regard to energy efficiency and hence operating costs. The present paper gives an overview of the currently applied technologies, including their thermodynamic and technical background. Areas of improvement are identified to derive process concepts for future large scale hydrogen liquefaction plants meeting the needs of clean energy applications with optimized energy efficiency and hence minimized operating costs. Compared to studies in this field, this paper focuses on application of new technology and innovative concepts which are either readily available or will require short qualification procedures. They will hence allow implementation in plants in the close future.

  10. Beta-cell mitochondrial carriers and the diabetogenic stress response.

    PubMed

    Brun, Thierry; Maechler, Pierre

    2016-10-01

    Mitochondria play a central role in pancreatic beta-cells by coupling metabolism of the secretagogue glucose to distal events of regulated insulin exocytosis. This process requires transports of both metabolites and nucleotides in and out of the mitochondria. The molecular identification of mitochondrial carriers and their respective contribution to beta-cell function have been uncovered only recently. In type 2 diabetes, mitochondrial dysfunction is an early event and may precipitate beta-cell loss. Under diabetogenic conditions, characterized by glucotoxicity and lipotoxicity, the expression profile of mitochondrial carriers is selectively modified. This review describes the role of mitochondrial carriers in beta-cells and the selective changes in response to glucolipotoxicity. In particular, we discuss the importance of the transfer of metabolites (pyruvate, citrate, malate, and glutamate) and nucleotides (ATP, NADH, NADPH) for beta-cell function and dysfunction. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26979549

  11. The mitochondrial pyruvate carrier in health and disease: To carry or not to carry?

    PubMed

    Bender, Tom; Martinou, Jean-Claude

    2016-10-01

    Mitochondria play a key role in energy metabolism, hosting the machinery for oxidative phosphorylation, the most efficient cellular pathway for generating ATP. A major checkpoint in this process is the transport of pyruvate produced by cytosolic glycolysis into the mitochondrial matrix, which is accomplished by the recently identified mitochondrial pyruvate carrier (MPC). As the gatekeeper for pyruvate entry into mitochondria, the MPC is thought to be of fundamental importance in establishing the metabolic programming of a cell. This is especially relevant in the context of the aerobic glycolysis, also known as the Warburg effect, which is a hallmark in many types of cancer, and MPC loss of function promotes cancer growth. Moreover, mitochondrial pyruvate uptake is needed for efficient hepatic gluconeogenesis and the regulation of blood glucose levels. In this review we discuss recent advances in our knowledge of the MPC, and we argue that it may offer a promising target in diseases like cancer and type 2 diabetes. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26826034

  12. Cryogenics for the MuCool Test Area (MTA)

    NASA Astrophysics Data System (ADS)

    Darve, Christine; Norris, Barry; Pei, Liujin

    2006-03-01

    MuCool Test Area (MTA) is a complex of buildings at Fermi National Accelerator Laboratory, which are dedicated to operate components of a cooling cell to be used for Muon Collider and Neutrino Factory R&D. The long-term goal of this facility is to test ionization cooling principles by operating a 25-liter liquid hydrogen (LH2) absorber embedded in a 5 Tesla superconducting solenoid magnet. The MTA solenoid magnet will be used with RF cavities exposed to a high intensity beam. Cryogens used at the MTA include LHe, LN2 and LH2. The latter dictates stringent system design for hazardous locations. The cryogenic plant is a modified Tevatron refrigerator based on the Claude cycle. The implementation of an in-house refrigerator system and two 300 kilowatt screw compressors is under development. The helium refrigeration capacity is 500 W at 14 K. In addition the MTA solenoid magnet will be batch-filled with LHe every 2 days using the same cryo-plant. This paper reviews cryogenic systems used to support the Muon Collider and Neutrino Factory R&D programs and emphasizes the feasibility of handling cryogenic equipment at MTA in a safe manner.

  13. Discoveries, metabolic roles and diseases of mitochondrial carriers: A review.

    PubMed

    Palmieri, Ferdinando; Monné, Magnus

    2016-10-01

    Mitochondrial carriers (MCs) are a superfamily of nuclear-encoded proteins that are mostly localized in the inner mitochondrial membrane and transport numerous metabolites, nucleotides, cofactors and inorganic anions. Their unique sequence features, i.e., a tripartite structure, six transmembrane α-helices and a three-fold repeated signature motif, allow MCs to be easily recognized. This review describes how the functions of MCs from Saccharomyces cerevisiae, Homo sapiens and Arabidopsis thaliana (listed in the first table) were discovered after the genome sequence of S. cerevisiae was determined in 1996. In the genomic era, more than 50 previously unknown MCs from these organisms have been identified and characterized biochemically using a method consisting of gene expression, purification of the recombinant proteins, their reconstitution into liposomes and transport assays (EPRA). Information derived from studies with intact mitochondria, genetic and metabolic evidence, sequence similarity, phylogenetic analysis and complementation of knockout phenotypes have guided the choice of substrates that were tested in the transport assays. In addition, the diseases associated to defects of human MCs have been briefly reviewed. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26968366

  14. [Homage to Pedro Planas].

    PubMed

    Canalda, K

    1990-12-01

    It has been known since the time of Claude Bernard that the "function makes the organ" and ensures its development. However, it took Planas to discover that the masticatory function is the principal factor related to the development of the jaw! Nonetheless, this function only attains its objective if it is physiologically normal, grinding of food taking place by alternative laterality, which can only occur according to Gysi with a balanced occlusion, in conformity with Hanau's rules: opening-closing type mastication as a result of another type of occlusion leads to maxillo-alveolar sub-development and lack of sufficient space. Neuro-Occlusal Rehabilitation (N.O.R.) attempts to detect the type of mastication and occlusion at an early age, to correct it as from the age of 3 years by selective grinding in order to establish alternative laterality: true prophylaxis. If the grinding function is not adequate because it has been corrected too late, Planas appliances are used. Post-orthodontic stability is remarkable as the treatment uses natural and normal means of development. PMID:2077860

  15. Linear and nonlinear dynamics of liquid planetary cores

    NASA Astrophysics Data System (ADS)

    Lathrop, D. P.

    2013-12-01

    This is the 50th anniversary of Ed Lorenz brilliant paper "Deterministic Nonperiodic Flow.'' Lorenz's work, along with many other founders' efforts, gave rise to the study of nonlinear dynamics. That field has allowed us to move beyond simple linear characterizations of nature, and to open up a deeper understanding of the Earth, other planets, and stars. Of the many things that make the Earth a habitable home, one is the existence of a planetary magnetic field generated in our liquid iron outer core. The generation process is known to be strongly nonlinear, and thereby almost certainly turbulent. Yet it is not a simple homogeneous isotropic turbulent flow, but is instead heavily modified by rotation and magnetic forces. We attempt to better understand the Earth's core using a three-meter liquid sodium laboratory model of the core. Our work in sodium in this system has just begun. The system exhibits a variety of behaviors with at least twelve different states, drawing different amounts of power, and causing varying levels of magnetic field amplification. In some states, rotation and magnetic fields cause the dynamics to simplify relative to more general turbulent flows in comparable conditions. Acknowledgements: I gratefully acknowledge my collaborators Daniel Zimmerman, Santiago Triana, Donald Martin, Nolan Balew, Henri-Claude Nataf, and Barbara Brawn-Cinani, and funding from the National Science Foundation Earth Sciences Instrumentation and Geophysics programs.

  16. STS-103 crew take part in CEIT in OPF 1

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility (OPF) bay 1, STS-103 Commander Curtis L. Brown Jr. sits in the command seat of the orbiter Discovery, inspecting the window. Brown and other crew members are at KSC to take part in a Crew Equipment Interface Test. The rest of the crew are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  17. Overview of Air Liquide refrigeration systems between 1.8 K and 200 K

    SciTech Connect

    Gondrand, C.; Durand, F.; Delcayre, F.; Crispel, S.; Baguer, G. M. Gistau

    2014-01-29

    Cryogenic refrigeration systems are necessary for numerous applications. Gas purification and distillation require temperatures between 15 K and 200 K depending on the application, space simulation chambers down to 15 K, superconductivity between 1.8 K and up to 75 K (magnets, cavities or HTS devices like cables, FCL, SMES, etc), Cold Neutron Sources between 15 and 20 K, etc. Air Liquide Advanced Technologies is designing and manufacturing refrigerators since 60 years to satisfy those needs. The step by step developments achieved have led to machines with higher efficiency and reliability. In 1965, reciprocating compressors and Joule Thomson expansion valves were used. In 1969, centripetal expanders began to be used. In 1980, oil lubricated screw compressors took the place of reciprocating compressors and a standard range of Claude cycle refrigerators was developed: the HELIAL series. 1980 was also the time for cryogenic centrifugal compressor development. In 2011, driven by the need for lower operational cost (high efficiency and low maintenance), cycle oil free centrifugal compressors on magnetic bearings were introduced instead of screw compressors. The power extracted by centripetal expanders was recovered. Based on this technology, a range of Turbo-Brayton refrigerators has been designed for temperatures between 40 K and 150 K. On-going development will enable widening the range of Turbo-Brayton refrigerators to cryogenic temperatures down to 15 K.. Cryogenic centrifugal circulators have been developed in order to answer to an increasing demand of 4 K refrigerators able to distribute cold power.

  18. Astronomical Dating of Monet's Paintings on the Normandy Coast

    NASA Astrophysics Data System (ADS)

    Olson, D. W.

    2016-01-01

    Claude Monet (1840-1926) is famous for landscapes accurately capturing the changing nature of seas and skies. Monet created almost two thousand paintings during his long career, and several hundred of these works depict the skies above the spectacular cliffs, arches, rocks, harbors, and beaches on the Normandy coast. Our Texas State University group made a research trip to Normandy in the summer of 2012 and found dozens of the locations where Monet set up his easel. Astronomical considerations of daylight, twilight, night skies, and tides can be used to enhance our understanding of the artist's creative process. Monet himself said, “I need the Sun or the cloudy weather to coincide again with the tide, which must be low or high in accordance with my motifs.” Astronomical methods can be used to help in dating these works, many of which have uncertain dates in the existing catalogues and literature about Monet in Normandy. Analysis using the direction of sunlight and the direction of shadows, combined with calculations of lunar phases and tide levels, meteorological records, and the artist's letters, enables us to determine the exact date and the precise time, accurate to the minute, when Monet observed the sky that inspired a painting.

  19. Chess as a Behavioral Model for Cognitive Skill Research: Review of Blindfold Chess by Eliot Hearst and John Knott

    PubMed Central

    Mechner, Francis

    2010-01-01

    This multifaceted work on chess played without sight of the pieces is a sophisticated psychologist's examination of this topic and of chess skill in general, including a detailed and comprehensive historical account. This review builds on Hearst and Knott's assertion that chess can provide a uniquely useful model for research on several issues in the area of cognitive skill and imagery. A key issue is the relationship between viewing a stimulus and mental imagery in the light of blindfold chess masters' consistent reports that they do not use or have images. This review also proposes a methodology for measuring and quantifying an individual's skill shortfall from a theoretical maximum. This methodology, based on a 1951 proposal by Claude Shannon, is applicable to any choice situation in which all the available choices are known. The proposed “Proficiency” measure reflects the equivalent number of “yes–no” questions that would have been required to arrive at a best choice, considering also the time consumed. As the measure provides a valid and nonarbitrary way to compare different skills and the effects of different independent variables on a given skill, it may have a wide range of applications in cognitive skill research, skill training, and education.

  20. STS-42 Preflight Background Briefing Life Sciences (MSFC)

    NASA Technical Reports Server (NTRS)

    1992-01-01

    A panel of scientists give an overview of the experiments that are to take place on-board the STS-42 Discovery mission. Ronald J. White, International Microgravity Laboratory (IML) Program Scientist, gives a general description of why going into space with IML is so important. Robert Snyder, IML Mission Scientist, describes other aspects of the microgravity environment. Millard Reschke, Principal Investigator (PI) Microgravity Vestibular Investigation (MVI), explains what MVI is and the effects of space on the vestibular system. David Heathcote, PI for the Gravitational Plant Physiology Facility (GPPF), describes the GPPF's on-board experiment involving the effects of light and gravity on plants. Claude Brillouet, Program Scientist of the Biorack Facility, gives an overview of the Biorack equipment and experiment. Alan Mortimer, Chief Life Sciences for the Canadian Space Agency (CSA), describes the on-board experiments for the long- and short-term effects of microgravity on humans and biotechnology (cell separation techniques). The men then answer questions from the press and NASA centers.

  1. Monocarboxylate transporters in the brain and in cancer.

    PubMed

    Pérez-Escuredo, Jhudit; Van Hée, Vincent F; Sboarina, Martina; Falces, Jorge; Payen, Valéry L; Pellerin, Luc; Sonveaux, Pierre

    2016-10-01

    Monocarboxylate transporters (MCTs) constitute a family of 14 members among which MCT1-4 facilitate the passive transport of monocarboxylates such as lactate, pyruvate and ketone bodies together with protons across cell membranes. Their anchorage and activity at the plasma membrane requires interaction with chaperon protein such as basigin/CD147 and embigin/gp70. MCT1-4 are expressed in different tissues where they play important roles in physiological and pathological processes. This review focuses on the brain and on cancer. In the brain, MCTs control the delivery of lactate, produced by astrocytes, to neurons, where it is used as an oxidative fuel. Consequently, MCT dysfunctions are associated with pathologies of the central nervous system encompassing neurodegeneration and cognitive defects, epilepsy and metabolic disorders. In tumors, MCTs control the exchange of lactate and other monocarboxylates between glycolytic and oxidative cancer cells, between stromal and cancer cells and between glycolytic cells and endothelial cells. Lactate is not only a metabolic waste for glycolytic cells and a metabolic fuel for oxidative cells, but it also behaves as a signaling agent that promotes angiogenesis and as an immunosuppressive metabolite. Because MCTs gate the activities of lactate, drugs targeting these transporters have been developed that could constitute new anticancer treatments. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26993058

  2. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, members of the STS-103 crew look at some of the equipment to be used during their mission. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  3. Disaster mythology and fact: Hurricane Katrina and social attachment.

    PubMed

    Jacob, Binu; Mawson, Anthony R; Payton, Marinelle; Guignard, John C

    2008-01-01

    Misconceptions about disasters and their social and health consequences remain prevalent despite considerable research evidence to the contrary. Eight such myths and their factual counterparts were reviewed in a classic report on the public health impact of disasters by Claude de Ville de Goyet entitled, The Role of WHO in Disaster Management: Relief, Rehabilitation, and Reconstruction (Geneva, World Health Organization, 1991), and two additional myths and facts were added by Pan American Health Organization. In this article, we reconsider these myths and facts in relation to Hurricane Katrina, with particular emphasis on psychosocial needs and behaviors, based on data gleaned from scientific sources as well as printed and electronic media reports. The review suggests that preparedness plans for disasters involving forced mass evacuation and resettlement should place a high priority on keeping families together--and even entire neighborhoods, where possible--so as to preserve the familiar and thereby minimize the adverse effects of separation and major dislocation on mental and physical health. PMID:18828410

  4. Space polypropulsion

    NASA Astrophysics Data System (ADS)

    Kellett, B. J.; Griffin, D. K.; Bingham, R.; Campbell, R. N.; Forbes, A.; Michaelis, M. M.

    2008-05-01

    Hybrid space propulsion has been a feature of most space missions. Only the very early rocket propulsion experiments like the V2, employed a single form of propulsion. By the late fifties multi-staging was routine and the Space Shuttle employs three different kinds of fuel and rocket engines. During the development of chemical rockets, other forms of propulsion were being slowly tested, both theoretically and, relatively slowly, in practice. Rail and gas guns, ion engines, "slingshot" gravity assist, nuclear and solar power, tethers, solar sails have all seen some real applications. Yet the earliest type of non-chemical space propulsion to be thought of has never been attempted in space: laser and photon propulsion. The ideas of Eugen Saenger, Georgii Marx, Arthur Kantrowitz, Leik Myrabo, Claude Phipps and Robert Forward remain Earth-bound. In this paper we summarize the various forms of nonchemical propulsion and their results. We point out that missions beyond Saturn would benefit from a change of attitude to laser-propulsion as well as consideration of hybrid "polypropulsion" - which is to say using all the rocket "tools" available rather than possibly not the most appropriate. We conclude with three practical examples, two for the next decades and one for the next century; disposal of nuclear waste in space; a grand tour of the Jovian and Saturnian moons - with Huygens or Lunoxod type, landers; and eventually mankind's greatest space dream: robotic exploration of neighbouring planetary systems.

  5. STS-103 Commander Brown introduces crew during interview at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Launch Pad 39B, STS-103 Commander Curtis L. Brown Jr. introduces the rest of the crew: (left to right) Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), and Claude Nicollier of Switzerland, who is also with ESA. As a preparation for launch, they have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  6. STS-103 Pilot Kelly and Commander Brown look over Discovery after landing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After landing at the Shuttle Landing Facility, STS-103 Pilot Scott J. Kelly (left) and Commander Curtis L. Brown Jr. (right) look at the tiles on orbiter Discovery. They and other crew members Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  7. STS-103 Commander Brown and his fiancee DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. and his fiancee, Ann Brickert, smile for the camera on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  8. STS-103 MS Clervoy and Commander Brown look over Discovery after landing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After landing at the Shuttle Landing Facility, STS-103 Mission Specialist Jean-Frangois Clervoy of France (left), with the European Space Agency (ESA), and Commander Curtis L. Brown Jr. (right) look over the orbiter Discovery. They and other crew members Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Claude Nicollier of Switzerland (also with ESA), completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  9. STS-103 MS Clervoy and Nicollier and Commander Brown look over Discovery after landing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After landing at the Shuttle Landing Facility, STS-103 Mission Specialists Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency, listen to a comment by Commander Curtis L. Brown Jr. while looking over the orbiter Discovery. Other members of the crew are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and John M. Grunsfeld (Ph.D.). The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  10. STS-103 Commander Brown answers question during interview at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. answers a question from the media about the mission. As a preparation for launch, the crew have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), and Claude Nicollier of Switzerland, who is also with ESA. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  11. STS-103 Commander Curtis Brown during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. gets ready to take the helm of a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith , C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), plus Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  12. STS-103 Commander Brown DEPARTs PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Amidst a flurry of activity, STS-103 Commander Curtis L. Brown Jr. disembarks from the bus which brought him to the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  13. VDAC2-specific cellular functions and the underlying structure.

    PubMed

    Naghdi, Shamim; Hajnóczky, György

    2016-10-01

    Voltage Dependent Anion-selective Channel 2 (VDAC2) contributes to oxidative metabolism by sharing a role in solute transport across the outer mitochondrial membrane (OMM) with other isoforms of the VDAC family, VDAC1 and VDAC3. Recent studies revealed that VDAC2 also has a distinctive role in mediating sarcoplasmic reticulum to mitochondria local Ca(2+) transport at least in cardiomyocytes, which is unlikely to be explained simply by the expression level of VDAC2. Furthermore, a strictly isoform-dependent VDAC2 function was revealed in the mitochondrial import and OMM-permeabilizing function of pro-apoptotic Bcl-2 family proteins, primarily Bak in many cell types. In addition, emerging evidence indicates a variety of other isoform-specific engagements for VDAC2. Since VDAC isoforms display 75% sequence similarity, the distinctive structure underlying VDAC2-specific functions is an intriguing problem. In this paper we summarize studies of VDAC2 structure and functions, which suggest a fundamental and exclusive role for VDAC2 in health and disease. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:27116927

  14. STS-61 crew utilizing Virtual Reality in training for HST repair mission

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut Jeffrey A. Hoffman, one of four crewmembers for STS-61 that will conduct scheduled spacewalks during the flight, wears a special helmet and gloves designed to assist in proper positioning near the telescope while on the end of the robot arm. Crewmembers are utilizing a new virtual reality training aid which assists in refining positioning patterns for Space Shuttle Endeavour's Remote Manipulator System (RMS) (36890); Astronaut Claude Nicollier looks at a computer display of the Shuttle's robot arm movements as Thomas D. Akers and Kathryn C. Thornton, mission specialists look on. Nicollier will be responsible for maneuvering the astronauts while they stand in a foot restraint on the end of the RMS arm (36891,36894); Hoffman wears a special helmet and gloves designed to assist in proper positioning near the telescope while on the end of the robot arm (35892); Nicollier looks at a computer display of the Shuttle's robot arm movements as Akers looks on (36893); While (l-r) Astron

  15. The XIIIth International Physiological Congress in Boston in 1929: American physiology comes of age.

    PubMed

    Rall, Jack A

    2016-03-01

    In the 19th century, the concept of experimental physiology originated in France with Claude Bernard, evolved in Germany stimulated by the teaching of Carl Ludwig, and later spread to Britain and then to the United States. The goal was to develop a physicochemical understanding of physiological phenomena. The first International Physiological Congress occurred in 1889 in Switzerland with an emphasis on experimental demonstrations. The XIIIth Congress, the first to be held outside of Europe, took place in Boston, MA, in 1929. It was a watershed meeting and indicated that American physiology had come of age. Meticulously organized, it was the largest congress to date, with over 1,200 participants from more than 40 countries. Getting to the congress was a cultural adventure, especially for the 400 scientists and their families from over 20 European countries, who sailed for 10 days on the S.S. Minnekahda. Many of the great physiologists of the world were in attendance, including 22 scientists who were either or would become Nobel Laureates. There were hundreds of platform presentations and many experimental demonstrations. The meeting was not without controversy as a conflict, still not completely settled, arose over the discovery of ATP. After the meeting, hundreds of participants made a memorable trip to the Marine Biological Laboratory at Woods Hole, MA, which culminated in a "good old fashioned Cape Cod Clambake." Although not as spectacular as the 1929 congress, the physiological congresses have continued with goals similar to those established more than a century ago. PMID:26847252

  16. Vision loss and hearing loss in painting and musical composition.

    PubMed

    Marmor, Michael F

    2014-07-01

    This article considers the impact of vision and hearing loss on great painters and musical composers. The visual work of Mary Cassatt, Georgia O'Keeffe, Edgar Degas, and Claude Monet all showed alterations as their vision failed. In contrast, Gabriel Fauré, Bedřich Smetana, and Ludwig von Beethoven wrote many of their best compositions while totally deaf, and Georg Friedrich Handel and Frederick Delius struggled to compose late in life when they lost their vision (although their hearing remained excellent). There are 2 major distinctions between the role of vision and hearing for these artistic disciplines. First, there is a surrogate means of "hearing" music, through the musical score, which allows composers to write and edit music while totally deaf. The greatest problem with deafness for a skilled composer is interference from internal noise (tinnitus). There is no surrogate for vision to allow a painter to work when the subject is a blur or the colors on the canvas cannot be distinguished. Second, although the appreciation of art is visual and that of music is auditory, the transcription of both art and musical composition is visual. Thus, visual loss does pose a problem for a composer accustomed to working with good sight, because it disrupts habitual methods of writing and editing music. PMID:24565744

  17. Stress in biology and medicine, role in aging.

    PubMed

    Robert, L; Labat-Robert, J

    2015-09-01

    In this review, we present a short description of the history of stress in the medical literature followed by a recapitulation of its mechanisms, from the cellular to the organismal level and its role in aging. The medical importance of stress was first taken up as a subject of experimental medicine by physiologists, starting from Claude Bernard's concept of the stability of the "milieu intérieur", altered by stress, followed by others, culminating recently by the elucidation of its mechanisms at the cellular and molecular level. These studies showed that oxidative stress is one of the most important and most frequent form of biological aggression. Its accumulation over time is important for the burnout syndrome and for neuronal aging. There is however a positive side to it also, redox signaling plays an important role in the functional coordination of cellular activities. These mechanisms, still to be more completely evaluated, have to be taken in account for planning efficient protective therapeutic interventions. PMID:26321500

  18. STS-103 Payload Commander Smith and his wife DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Payload Commander Steven L. Smith and his wife, Peggy, smile for the camera on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  19. STS-103 M.S. Steven Smith during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist Steven L. Smith gets ready to practice driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  20. STS-103 Pilot Kelly and MS Clervoy and Smith DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Pilot Scott J. Kelly holds his daughter as he talks to Mission Specialists and fellow crew members Jean-Frangois Clervoy of France and Steven L. Smith on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr. and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  1. STS-103 Mission Specialist Smith suits up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After donning his launch and entry suit, sts-103 Mission Specialist Steven L. Smith shows a positive attitude over the second launch attempt for Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Smith and other crew members Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  2. STS-103 M.S. John Grunsfeld during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist John M. Grunsfeld (Ph.D.) gets ready to take the wheel of a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  3. STS-103 Pilot Scott Kelly and MS John Grunsfeld try on oxygen masks

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the bunker at Launch Pad 39B, STS-103 Pilot Scott J. Kelly (left) and Mission Specialist John M. Grunsfeld (Ph.D.) (right) try on oxygen masks during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  4. Ocean energy conversion systems annual research report

    SciTech Connect

    Not Available

    1981-03-01

    Alternative power cycle concepts to the closed-cycle Rankine are evaluated and those that show potential for delivering power in a cost-effective and environmentally acceptable fashion are explored. Concepts are classified according to the ocean energy resource: thermal, waves, currents, and salinity gradient. Research projects have been funded and reported in each of these areas. The lift of seawater entrained in a vertical steam flow can provide potential energy for a conventional hydraulic turbine conversion system. Quantification of the process and assessment of potential costs must be completed to support concept evaluation. Exploratory development is being completed in thermoelectricity and 2-phase nozzles for other thermal concepts. Wave energy concepts are being evaluated by analysis and model testing with present emphasis on pneumatic turbines and wave focussing. Likewise, several conversion approaches to ocean current energy are being evaluated. The use of salinity resources requires further research in membranes or the development of membraneless processes. Using the thermal resource in a Claude cycle process as a power converter is promising, and a program of R and D and subsystem development has been initiated to provide confirmation of the preliminary conclusion.

  5. "The Civil Rights Movement of the 1990s?": The anti-abortion movement and the struggle for racial justice.

    PubMed

    Hughes, Richard L

    2006-01-01

    In 1964, Claude and Jeanne Nolen, who were white, joined an interracial NAACP team intent on desegregating local restaurants in Austin, Texas as a test of the recently passed Civil Rights ACt. Twenty-five years later, the Nolens pleaded "no contest" in a courtroom for their continued social activism. This time the issue was not racial segregation, but rather criminal trespassing for blockading abortion clinics with Operation Rescue. The Nolens served prison sentences for direct action protests that they believe stemmed from the same commitment to Christianity and social justice as the civil rights movements. Despite its relationship to political and cultural conservatism, the anti-abortion movement since Roe v. Wade (1973) was also a product of the progressive social movements of the turbulent sixties. Utilizing oral history interviews and organizational literature, the article explores the historical context of the anti-abortion movement, specifically how the lengthy struggle for racial justice shaped the rhetoric, tactics, and ideology of the anti-abortion activists. Even after political conservatives dominated the movement in the 1980s, the successes and failures of the sixties provided a cultural lens through which grassroots anti-abortion activists forged what was arguably the largest movement of civil disobedience in American history. PMID:17115517

  6. Cryogenics for the MuCool Test Area (MTA)

    SciTech Connect

    Darve, Christine; Norris, Barry; Pei, Liujin

    2006-03-20

    MuCool Test Area (MTA) is a complex of buildings at Fermi National Accelerator Laboratory, which are dedicated to operate components of a cooling cell to be used for Muon Collider and Neutrino Factory R and D. The long-term goal of this facility is to test ionization cooling principles by operating a 25-liter liquid hydrogen (LH2) absorber embedded in a 5 Tesla superconducting solenoid magnet. The MTA solenoid magnet will be used with RF cavities exposed to a high intensity beam. Cryogens used at the MTA include LHe, LN2 and LH2. The latter dictates stringent system design for hazardous locations. The cryogenic plant is a modified Tevatron refrigerator based on the Claude cycle. The implementation of an in-house refrigerator system and two 300 kilowatt screw compressors is under development. The helium refrigeration capacity is 500 W at 14 K. In addition the MTA solenoid magnet will be batch-filled with LHe every 2 days using the same cryo-plant. This paper reviews cryogenic systems used to support the Muon Collider and Neutrino Factory R and D programs and emphasizes the feasibility of handling cryogenic equipment at MTA in a safe manner.

  7. Overview of Air Liquide refrigeration systems between 1.8 K and 200 K

    NASA Astrophysics Data System (ADS)

    Gondrand, C.; Durand, F.; Delcayre, F.; Crispel, S.; Baguer, G. M. Gistau

    2014-01-01

    Cryogenic refrigeration systems are necessary for numerous applications. Gas purification and distillation require temperatures between 15 K and 200 K depending on the application, space simulation chambers down to 15 K, superconductivity between 1.8 K and up to 75 K (magnets, cavities or HTS devices like cables, FCL, SMES, etc), Cold Neutron Sources between 15 and 20 K, etc. Air Liquide Advanced Technologies is designing and manufacturing refrigerators since 60 years to satisfy those needs. The step by step developments achieved have led to machines with higher efficiency and reliability. In 1965, reciprocating compressors and Joule Thomson expansion valves were used. In 1969, centripetal expanders began to be used. In 1980, oil lubricated screw compressors took the place of reciprocating compressors and a standard range of Claude cycle refrigerators was developed: the HELIAL series. 1980 was also the time for cryogenic centrifugal compressor development. In 2011, driven by the need for lower operational cost (high efficiency and low maintenance), cycle oil free centrifugal compressors on magnetic bearings were introduced instead of screw compressors. The power extracted by centripetal expanders was recovered. Based on this technology, a range of Turbo-Brayton refrigerators has been designed for temperatures between 40 K and 150 K. On-going development will enable widening the range of Turbo-Brayton refrigerators to cryogenic temperatures down to 15 K.. Cryogenic centrifugal circulators have been developed in order to answer to an increasing demand of 4 K refrigerators able to distribute cold power.

  8. STS-103 M.S. Michael Foale during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist C. Michael Foale (Ph.D.) is ready to take his turn at driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith , John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  9. Developing computer-based training programs for basic mammalian histology: Didactic versus discovery-based design

    NASA Astrophysics Data System (ADS)

    Fabian, Henry Joel

    Educators have long tried to understand what stimulates students to learn. The Swiss psychologist and zoologist, Jean Claude Piaget, suggested that students are stimulated to learn when they attempt to resolve confusion. He reasoned that students try to explain the world with the knowledge they have acquired in life. When they find their own explanations to be inadequate to explain phenomena, students find themselves in a temporary state of confusion. This prompts students to seek more plausible explanations. At this point, students are primed for learning (Piaget 1964). The Piagetian approach described above is called learning by discovery. To promote discovery learning, a teacher must first allow the student to recognize his misconception and then provide a plausible explanation to replace that misconception (Chinn and Brewer 1993). One application of this method is found in the various learning cycles, which have been demonstrated to be effective means for teaching science (Renner and Lawson 1973, Lawson 1986, Marek and Methven 1991, and Glasson & Lalik 1993). In contrast to the learning cycle, tutorial computer programs are generally not designed to correct student misconceptions, but rather follow a passive, didactic method of teaching. In the didactic or expositional method, the student is told about a phenomenon, but is neither encouraged to explore it, nor explain it in his own terms (Schneider and Renner 1980).

  10. UCPs, at the interface between bioenergetics and metabolism.

    PubMed

    Bouillaud, Frédéric; Alves-Guerra, Marie-Clotilde; Ricquier, Daniel

    2016-10-01

    The first member of the uncoupling protein (UCP) family, brown adipose tissue uncoupling protein 1 (UCP1), was identified in 1976. Twenty years later, two closely related proteins, UCP2 and UCP3, were described in mammals. Homologs of these proteins exist in other organisms, including plants. Uncoupling refers to a deterioration of energy conservation between substrate oxidation and ADP phosphorylation. Complete energy conservation loss would be fatal but fine-tuning can be beneficial for processes such as thermogenesis, redox control, and prevention of mitochondrial ROS release. The coupled/uncoupled state of mitochondria is related to the permeability of the inner membrane and the proton transport mediated by activated UCPs underlies the uncoupling activity of these proteins. Proton transport by UCP1 is activated by fatty acids and this ensures thermogenesis. In vivo in absence of this activation UCP1 remains inhibited with no transport activity. A similar situation now seems unlikely for UCP2 and UCP3 and while activation of their proton transport has been described its physiological relevance remains uncertain and their influence can be envisaged as a result of another transport pathway that takes place in the absence of activation. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:27091404

  11. STS-103 crew take part in CEIT in PHSF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, four STS-103 crew members check the Flight Support System avionics to be used for repair and upgrade of the Hubble Space Telescope. The crew are at KSC to take part in a Crew Equipment Interface Test. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  12. Living Together Apart in France and the United States

    PubMed Central

    Martin, Claude; Cherlin, Andrew; Cross-Barnet, Caitlin

    2014-01-01

    Union formation involves a number of stages, as does union dissolution, and new couples often spend an initial period in a non-cohabiting intimate relationship. Yet while certain couples never share the same dwelling, “living apart together”1 has not developed widely as a long-term lifestyle option. Claude Martin in France, and Andrew Cherlin and Caitlin Cross-Barnet in the United States have studied a symmetrical phenomenon, that of couples who continue to live together while considering themselves to be separated. In this article, they draw together their analyses to describe an arrangement which, while marginal, reveals situations where residential separation is not possible, either because of the need to keep up appearances, often for the children’s sake, or because total separation is too frightening or living in separate homes is unaffordable. Beyond the differences between the two countries and the two survey fields, the authors analyse the ways in which persons who “live together apart” describe their loveless relationship that has led to explicit conjugal separation within a shared home. PMID:25170338

  13. Gay re-readings of the Harlem Renaissance poets.

    PubMed

    Woods, G

    1993-01-01

    In the light of the long-established fact of their homosexuality or bisexuality, it is high time for the cluster of "Negro Renaissance" poets, Countee Cullen, Langston Hughes, Claude McKay, and Richard Bruce Nugent, to be reappraised by and for gay readers. This paper seeks to develop gay reading strategies in relation to the poems of these writers, in order to reveal for contemporary readers likely subtexts which, at the time of their writing, were publicly read as bearing on race alone. It is often possible to read a particular poem as referring (in images such as that of the social outcast) to either racial or sexual oppression, interchangeably; and possibly, therefore, to both at once, by way of an implicit comparison. Likewise, poems on miscegenation can just as well be read, via the theme of forbidden love, as referring to homosexuality. The fact that most published critical readings deal only with the racial issue does not invalidate the likelihood that the poem can be, and indeed requires to be, read as referring, also, to sexuality. Gay readings emerge, then, not merely from these writers' representations of attractive men and boys, but also in the midst of their most famously anti-racist themes. PMID:8113612

  14. STS-103 perfect night-time landing for Space Shuttle Discovery

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The orbiter Discovery looks like a blue ghost as it drops from the darkness onto lighted runway 33 at KSC's Shuttle Landing Facility. After traveling more than 3,267,000 miles on a successful eight-day mission to service the Hubble Space Telescope, the orbiter touches down at 7:00:47 p.m. EST. Aboard are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who spent the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  15. Biochemistry and physiology within the framework of the extended synthesis of evolutionary biology.

    PubMed

    Vianello, Angelo; Passamonti, Sabina

    2016-01-01

    Functional biologists, like Claude Bernard, ask "How?", meaning that they investigate the mechanisms underlying the emergence of biological functions (proximal causes), while evolutionary biologists, like Charles Darwin, asks "Why?", meaning that they search the causes of adaptation, survival and evolution (remote causes). Are these divergent views on what is life? The epistemological role of functional biology (molecular biology, but also biochemistry, physiology, cell biology and so forth) appears essential, for its capacity to identify several mechanisms of natural selection of new characters, individuals and populations. Nevertheless, several issues remain unsolved, such as orphan metabolic activities, i.e., adaptive functions still missing the identification of the underlying genes and proteins, and orphan genes, i.e., genes that bear no signature of evolutionary history, yet provide an organism with improved adaptation to environmental changes. In the framework of the Extended Synthesis, we suggest that the adaptive roles of any known function/structure are reappraised in terms of their capacity to warrant constancy of the internal environment (homeostasis), a concept that encompasses both proximal and remote causes. PMID:26861860

  16. [Ethical principles in human scientific research].

    PubMed

    Cruz-Coke, R

    1994-07-01

    Hippocrates was the first physician to use the scientific method to find rational and not religious or mythic causes, for the etiology of diseases. Hippocrates and Aristoteles did not dare to dissect the human body. Afterwards however, many scientists such as Herophilus, Erasitastrus, Vesalus and Fallopio, performed experiments in human beings using vivisection. According to that age's ideas, there was no cruelty in performing vivisection in criminals, since useful knowledge for the progress of medicine and relief of diseases was obtained. Only during the nineteenth century and with Claude Bernard (1865), the ethical principles of systematic scientific research in humans were defined. These principles were violated by nazi physicians during Hitler's dictatorship in Germany (1933-1945). As a response to these horrors, the Ethical Codes of Nuremberg (1947) and Geneva (1948), that reestablished all the strength of Hippocratic principles, were dictated. The Nuremberg rules enact that a research subject must give a voluntary consent, that the experiment must by necessary and exempt of death risk, that the research must be qualified and that the experiment must be discontinued if there is a risk for the subject. The Geneva statement is a modernized hippocratic oath that protects patient's life above all. These classical rules, in force at the present time, are the essential guides that must be applied by physicians and researchers. PMID:7732235

  17. Adaptive homeostasis.

    PubMed

    Davies, Kelvin J A

    2016-06-01

    Homeostasis is a central pillar of modern Physiology. The term homeostasis was invented by Walter Bradford Cannon in an attempt to extend and codify the principle of 'milieu intérieur,' or a constant interior bodily environment, that had previously been postulated by Claude Bernard. Clearly, 'milieu intérieur' and homeostasis have served us well for over a century. Nevertheless, research on signal transduction systems that regulate gene expression, or that cause biochemical alterations to existing enzymes, in response to external and internal stimuli, makes it clear that biological systems are continuously making short-term adaptations both to set-points, and to the range of 'normal' capacity. These transient adaptations typically occur in response to relatively mild changes in conditions, to programs of exercise training, or to sub-toxic, non-damaging levels of chemical agents; thus, the terms hormesis, heterostasis, and allostasis are not accurate descriptors. Therefore, an operational adjustment to our understanding of homeostasis suggests that the modified term, Adaptive Homeostasis, may be useful especially in studies of stress, toxicology, disease, and aging. Adaptive Homeostasis may be defined as follows: 'The transient expansion or contraction of the homeostatic range in response to exposure to sub-toxic, non-damaging, signaling molecules or events, or the removal or cessation of such molecules or events.' PMID:27112802

  18. Dynamical systems theory and applications

    NASA Astrophysics Data System (ADS)

    Awrejcewicz, Jan

    2006-08-01

    The 7th International Conference devoted to "Dynamical Systems-Theory and Applications" hold in 8-11 December, 2003 in Łódź, Poland, and it was organized by the staff of Department of Automatics and Biomechanics of the Technical University of Łódź. It was financially supported by the Rector of the Technical University of Łódź and the Department of Education and Physical Culture of the Łódź City Hall. The members of the International Scientific Committee included: Igor V. Andrianov (Dniepropetrovsk), Jan Awrejcewicz (Łódź), Iliya Blekhman (Sankt Petersburg), Roman Bogacz (Warszawa), Dick van Campen (Eindhoven), Zbigniew Engel (Kraków), Lothar Gaul (Stuttgart), Józef Giergiel (Kraków), Michał Kleiber (Warszawa), Vadim A. Krysko (Saratov), Włodzimierz Kurnik (Warszawa), Claude-Henri Lamarque (Lyon), Leonid I. Manevitch (Moscow), Jan Osiecki (Warszawa), Wiesaw Ostachowicz (Gdańsk), Ladislav Pust (Prague), Giuseppe Rega (Rome), Tsuneo Someya (Tokyo), Zbigniew Starczewski (Warszawa), Eugeniusz Świtoński (Gliwice), Andrzej Tylikowski (Warszawa), Tadeusz Uhl (Kraków), Aleksander F. Vakakis (Illinois), Józef Wojnarowski (Gliwice).

  19. A physiologist's view of homeostasis.

    PubMed

    Modell, Harold; Cliff, William; Michael, Joel; McFarland, Jenny; Wenderoth, Mary Pat; Wright, Ann

    2015-12-01

    Homeostasis is a core concept necessary for understanding the many regulatory mechanisms in physiology. Claude Bernard originally proposed the concept of the constancy of the "milieu interieur," but his discussion was rather abstract. Walter Cannon introduced the term "homeostasis" and expanded Bernard's notion of "constancy" of the internal environment in an explicit and concrete way. In the 1960s, homeostatic regulatory mechanisms in physiology began to be described as discrete processes following the application of engineering control system analysis to physiological systems. Unfortunately, many undergraduate texts continue to highlight abstract aspects of the concept rather than emphasizing a general model that can be specifically and comprehensively applied to all homeostatic mechanisms. As a result, students and instructors alike often fail to develop a clear, concise model with which to think about such systems. In this article, we present a standard model for homeostatic mechanisms to be used at the undergraduate level. We discuss common sources of confusion ("sticky points") that arise from inconsistencies in vocabulary and illustrations found in popular undergraduate texts. Finally, we propose a simplified model and vocabulary set for helping undergraduate students build effective mental models of homeostatic regulation in physiological systems. PMID:26628646

  20. Does Stereotype Threat Affect Post-Course Scores on the Astronomy Diagnostic Test?

    NASA Astrophysics Data System (ADS)

    Deming, G. L.; Hufnagel, B.; Landato, J. M.; Hodari, A. K.

    2003-12-01

    During the 1990s, Claude Steele and others demonstrated that women mathematics students under-performed while men over-performed on selected GRE questions when told that the exam could differentiate by gender. Stereotype threat is triggered for these women when they fear someone else may negatively stereotype them, and therefore, their performance is affected. In a limited study involving 229 students, we investigated the effect of stereotype threat on performance on the Astronomy Diagnostic Test (ADT). The ADT was administered as a pre-test in four introductory astronomy classes intended for non-science majors. The same professors taught pairs of classes at the University of Maryland, a large research institution, and W. R. Harper College, a small liberal arts school. The classes were treated the same until the final day before the post-course ADT was given. One "threatened" class at each campus was told that gender mattered so they should be sure to include it on the ADT. The "control" classes were told that gender does not matter. The results show no stereotype threat effect on the women in these introductory classes. The university men did slightly over-perform at low statistical significance. As Steele suggested, students must identify with a subject in order to strongly invoke a stereotype threat. This research was supported in part by the National Science Foundation through grants REC-0089239 to GLD, DGE-97014489 to BH, and DGE-9714452 for AKH.

  1. The discovery and rediscovery of oxygen.

    PubMed

    Sternbach, George L; Varon, Joseph

    2005-02-01

    The therapeutic use of oxygen was pioneered in the early 20(th) century by the respiratory physiologist John Scott Haldane. His work followed Claude Bernard's description of the toxic effects of carbon monoxide. Haldane, having also observed the effects of carbon monoxide poisoning, became aware of the therapeutic benefits of oxygen in this condition. He was also an advocate of oxygen as a therapeutic agent in other respiratory illness, and made efforts to define how the gas could best be administered. The history of identification of oxygen as a chemical element is convoluted. In the 17(th) century, the controversial John Mayow suggested that only a portion of air was necessary for sustaining life. Mayow's work was largely overlooked during his lifetime, and his insight was subsequently eclipsed by the phlogiston theory, an erroneous concept widely believed for nearly a century after his death. This theory was ultimately disproved by Joseph Priestley in 1774. Although the point of primacy is somewhat contentious, Priestley shares the distinction of discovering elemental oxygen with Antoine-Laurent Lavoisier, the French chemist, and Carl Wilhelm Scheele, the Swedish apothecary. PMID:15707822

  2. STS-103 Mission Highlights Resource Tape (1 of 2)

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The STS-103 flight crew, Commander Curtis L. Brown, Pilot Scott J. Kelly, Mission Specialists Steven L. Smith, C. Michael Foale, John M. Grunsfeld, Claude Nicollier, and Jean-Francois Clervoy, are seen performing pre-launch activities such as crew suit-up, and ride out to the launch pad for a night launch. Also, included are various panoramic views of the shuttle on the pad. The crew is readied in the White Room for their mission. After the closing of the hatch and arm retraction, launch activities are shown including countdown, engine ignition, launch, and the separation of the Solid Rocket Boosters. Once on-orbit the primary objective is to capture and service the Hubble Space Telescope. Included are various live shots of the payload bay showing the flight support system, the orbiter replacement unit carrier and the forward fixture that house the new Fine Guidance System (FGS). Smith and Grunsfeld replaces and changes the sensor units during the first space walk of this mission. The second space walk by Nicollier and Foale includes the changing of the computer and installation of the FGS. This is tape 1 of 2, tape 2 has a report number of NONP-NASA-VT-2000036031.

  3. PREFACE: 28th Winter Workshop on Nuclear Dynamics (WWND-28)

    NASA Astrophysics Data System (ADS)

    Bellwied, Rene; Pruneau, Claude A.

    2012-11-01

    These are the proceedings of the 28th Winter Workshop on Nuclear Dynamics, which was held in Dorado Del Mar, Puerto Rico. As in previous years the unique character of this conference series has allowed us to bring together nuclear scientists from very different fields to discuss recent progress and scientific achievements. At the high-energy frontier very exciting results from heavy-ion collisions at the LHC were shown. At the lower energies the RHIC beam energy scan is underway to span the gap between the SPS and RHIC and search for the QCD phase transition and critical phenomena in the nuclear matter phase diagram. The nuclear structure and astrophysics communities have started to construct dedicated facilities at Michigan State University (F-RIB) and the GSI in Germany (FAIR). Theory progress is made across all these different energy regimes, and the new data, in particular from the LHC and RHIC, are motivating more detailed modeling and a deeper understanding of the underlying physics. These proceedings of the 28th Winter Workshop on Nuclear Dynamics again provide a snapshot of the status of the field. The articles, many of which are written by some of the most promising young scientists in the field, are documenting the excitement and achievements that are characteristic for all subfields of nuclear science. Rene Bellwied (University of Houston) Claude Pruneau (Wayne State University)

  4. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, a member of the STS-103 crew checks out rib clamp to be used on the Shield Shell Replacement Fabric (SSRF) task on repair of the Hubble Space Telescope. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  5. STS-103 Flight Day 3 Highlights and Crew Activities Report

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Highlights of the third day of the STS-103 mission on board the space shuttle Discovery are shown in this videotape. The mission was led by Commander Curtis L. Brown, with Pilot Scott J Kelly, and Mission Specialists Steven L. Smith, Jean-Francois Clervoy, John M. Grunsfeld, Michael Foale, and Claude Nicollier. The main purpose of the mission was to service the Hubble Space Telescope (HST). The primary objective of the mission was to replace all six of the gyroscopes that make up the three Rate Sensor Units. In addition the Astronauts installed a new computer. During the third day when Discovery reached a point about 35 feet from Hubble, astronaut Jean-Francois Clervoy used the robot arm to capture the telescope's grapple fixture located midway up the HST structure. The approach to the HST is described and the actual maneuver aimed at retrieving the telescope is also described. The video includes actual live views of the HST in the shuttle's service bay, the shuttle, and shots of Johnson mission control. .

  6. Mathematical modeling of a Fermilab helium liquefier coldbox

    SciTech Connect

    Geynisman, M.G.; Walker, R.J.

    1995-12-01

    Fermilab Central Helium Liquefier (CHL) facility is operated 24 hours-a-day to supply 4.6{degrees}K for the Fermilab Tevatron superconducting proton-antiproton collider Ring and to recover warm return gases. The centerpieces of the CHL are two independent cold boxes rated at 4000 and 5400 liters/hour with LN{sub 2} precool. These coldboxes are Claude cycle and have identical heat exchangers trains, but different turbo-expanders. The Tevatron cryogenics demand for higher helium supply from CHL was the driving force to investigate an installation of an expansion engine in place of the Joule-Thompson valve. A mathematical model was developed to describe the thermo- and gas-dynamic processes for the equipment included in the helium coldbox. The model is based on a finite element approach, opposite to a global variables approach, thus providing for higher accuracy and conversion stability. Though the coefficients used in thermo- and gas-dynamic equations are unique for a given coldbox, the general approach, the equations, the methods of computations, and most of the subroutines written in FORTRAN can be readily applied to different coldboxes. The simulation results are compared against actual operating data to demonstrate applicability of the model.

  7. Farmed deer: a large animal model for stress.

    PubMed

    Griffin, J F; Thomson, A J

    1998-09-01

    In the early classic period it was suggested by Heracleitus that a static unchanged state was not the natural condition, but rather that the capacity to undergo constant change was intrinsic to all living things. After that, Empedoeles, circa 500 BC, proposed that for living organisms to survive they require a harmonious mixture of elements. Hippocrates, around 400 BC, developed this concept further by suggesting that health is a state of harmonious balance of these elements, equating disease to a state of disharmony and introducing the concept that nature heals disease (Noysvn Fyseiw/atrui). Soon after, Epicurus extended these ideas to include among these healing forces, the mind, writing that imperturbability of mind is desirable. Claude Bernard introduced the concept of the milieu interieur or the internal physiologic environment, describing its constancy as essential in an external environment typified by its variability. Walter Cannon described Bernard's constancy as Homeostasis and identified the "fight or flight reflex," linking the adaptive response and catecholamine secretion, with extreme levels of activation-producing pathology. Selye outlined four stages of the stress response: 1) the "alarm reaction" characterized by an immediate activation of the sympathetic-adrenomedullary axis (SA); 2) a "resistance phase" characterized by hypothalamic pituitary-adrenal axis (HPA) activation; 3) a stage of adrenal hypertrophy, gastrointestinal ulceration, along with thymic and lymphoid atrophy; and 4) an exhaustion phase and finally death (1). PMID:9785049

  8. The history of stress hyperglycaemia.

    PubMed

    Balasanthiran, A; Shotliff, K

    2015-01-01

    Stress hyperglycaemia, is a common phenomenon, frequently associated with adverse outcomes in a number of prevalent conditions including myocardial infarction and stroke. Knowledge on stress hyperglycaemia evolved in tandem with knowledge relating to homeostasis, stress and disease and involved some of the world's most eminent thinkers. Despite this, it still remains under-recognised. This paper illustrates significant points in the history of stress hyperglycaemia, from antiquity through to the present day, as well as the challenges faced in translating research into clinical benefit for patients. Profiles of significant protagonists including Claude Bernard, Walter Cannon and Hans Seyle are presented, as well their roles in the emergence of modern-day terminology and pathophysiological models. Major themes such as 'fight or flight' and homeostasis are central to this discussion. Closer to the present day, the role of stress hyperglycaemia in a number of common medical conditions is explored in more detail. Contention around evidence for treatment and the future risk of diabetes mellitus are also discussed. PMID:26517107

  9. Determinism and probability in the development of the cell theory.

    PubMed

    Duchesneau, François

    2012-09-01

    A return to Claude Bernard's original use of the concept of 'determinism' displays the fact that natural laws were presumed to rule over all natural processes. In a more restricted sense, the term boiled down to a mere presupposition of constant determinant causes for those processes, leaving aside any particular ontological principle, even stochastic. The history of the cell theory until around 1900 was dominated by a twofold conception of determinant causes. Along a reductionist trend, cells' structures and processes were supposed to be accounted for through their analysis into detailed partial mechanisms. But a more holistic approach tended to subsume those analytic means and the mechanism involved under a program of global functional determinations. When mitotic and meiotic sequences in nuclear replication were being unveiled and that neo-Mendelian genetics was being grafted onto cytology and embryology, a conception of strict determinism at the nuclear level, principally represented by Wilhelm Roux and August Weismann, would seem to rule unilaterally over the mosaic interpretation of the cleavage of blastomeres. But, as shown by E.B. Wilson, in developmental processes there occur contingent outcomes of cell division which observations and experiments reveal. This induces the need to admit 'epigenetic' determinants and relativize the presumed 'preformation' of thedevelopmental phases by making room for an emergent order which the accidental circumstances of gene replication would trigger on. PMID:22542690

  10. [Protoplasm, coagulation and colloids : Forgotten chapter in the research history of anesthesia between Zeitgeist and paradigm].

    PubMed

    Perouansky, M

    2015-05-01

    The historically most important mechanistic theories attributed the fundamental cause of anesthesia to interactions betweeen anesthetics and proteins as early as the 1870s. According to the underlying thought, the resulting changes in the consistency of cellular protoplasm were the cause of the anesthetized state of the whole organism.These protoplasm coagulation theories, as they were collectively referred to, brought the contemporary enthusiasm for protoplasm, the rapid advances in colloid chemistry and the unified theory of narcosis proclamed by Claude Bernard under a unified mechanistic theory that reflected the Zeitgeist of the epoch.This research effort, on the intersection of the developing disciplines of cellular biology and colloid chemistry, lasted for almost a century. It involved scientists of worldwide reputation and resulted in a number of elegant theories. Contrary to widespread opinion, proteins and not lipids were recognized and investigated first as the critical molecular target of anesthetics more than a century prior to their much publicized rediscovery in 1984.The protoplasm coagulation theories of anesthesia were pursued after the First World War across ideological trenches by scientists in Europe, the Soviet Union and the United States. They united research in anesthesia with research of fundamental cell biology.In contrast to the much less fruitful lipid theories, protoplasm coagulation theories are largely forgotten without leaving a trace in contemporary discussions of the history of anesthesia. For many tyears, however, they constituted an essential part of fundamental anesthetic research and must therefore be mentioned in any historical review. PMID:25776209

  11. STS-103 crew take part in CEIT in PHSF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test in the Payload Hazardous Servicing Facility, members of the STS-103 crew check out the Flight Support System (FSS)from above and below. The FSS is part of the primary payload on the mission to repair the Hubble Space Telescope. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  12. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, some of the STS-103 crew look over lubrication devices to be used during their mission. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  13. Radiative transfer and type Ia supernovae spectra analysis in the context of supernovae factory

    NASA Astrophysics Data System (ADS)

    Bongard, Sebastien

    This co-supervised dissertation was conducted in collaboration between The University of Oklahoma City (USA) and University Claude Bernard of Lyon (France). It addresses the radiative transfer issue in type Ia supernovae expanding envelopes, in the context of the SupernovaFactory. We used the multi-purpose radiative transfer code phoenix, developed by P. Hauschildt, F. Allard and E. Baron to produce a grid of synthetic spectra sampling dates from 10 to 25 days after explosion and bolometric magnitudes from -18.0 to -19.7. We also developed an adaptive grid scheme in order to stabilize phoenix convergence. We showed the spectrum formation in SNeIa around maximum light to be a multi- layered process involving regions from 5000 km per s to 20000 km per s, interacting not only through scattering but also through pure emission. This new understanding allowed us to introduce a new spectral indicators we called RSiSu, which can be used to measure SNeIa blue magnitudes with a precision comparable to the stretch factor. This makes it possible to independently constraint the evolutionary effect on SNeIa that are of crucial importance for high z surveys.

  14. A Analytical and a Numerical Study in Field Theory.

    NASA Astrophysics Data System (ADS)

    Olynyk, Kirk Oliver

    In Chapter I. the low-energy sensitivity of the Weinberg-Salem model to a strongly interacting Higgs-boson sector is investigated. In order to catalog all possible heavy Higgs boson effects, a gauged nonlinear (sigma)-model is used, in which the Higgs mass of the linear theory (M(,H)), assumes the role of a cutoff. Radiative corrections to several experimental observables are calculated. However, the effects are small; the leading sensitivities are proportional to g('2)ln(M(,H)). Chapter II. is a report on a collaboration with Claude Bernard and Terry Draper, in which we calculate hadron masses and magnetic moments in the quenched approximation to lattice QCD, using Monte Carlo and Gauss-Seidel methods. For the mass computation, we have quite good statistics; in addition, our lattice is long enough in the "time" direction to make a rather clear separation of the lowest lying hadrons from their radial excitations. We find mass ratios which are far from experimental values; there is evidence that this may be due to the small spatial size of the lattice (which, however, is as large or larger than that used in most previous computations). Semi-quantitative explanations of spatial volume and time-length effects are given. For the magnetic moments, the situation is somewhat better, presumably because the moment calculation is really a qualitative test of the constituent quark model.

  15. ESPAS: the European e-science platform to access near-Earth space data (Invited)

    NASA Astrophysics Data System (ADS)

    Belehaki, A.; Hapgood, M. A.; Ritschel, B.; Manola, N.

    2013-12-01

    Lebesis, Bruno Zolesi, Tatjana Gerzen, Ingemar Häggström, Anna Charisi, Ivan Galkin, Jurgen Watermann, Matthew Angling, Timo Asikainen, Alan Aylward, Henrike Barkmann, Peter Bergqvist, Andrew Bushell, Fabien Darrouzet, Dimitris Dialetis, Carl-Fredrik Enell, Daniel Heynderickx, Norbert Jakowski, Magnar Johnsen, Jean Lilensten, Ian McCrea, Kalevi Mursula, Bogdan Nicula, Michael Pezzopane, Viviane Pierrard, Bodo Reinisch, Bernd Ritschel, Luca Spogli, Iwona Stanislawska, Claudia Stolle, Eija Tanskanen, Ioanna Tsagouri, Esa Turunen, Thomas Ulich, Matthew Wild, Tim Yeoman

  16. Galileo in-situ dust measurements and the significance of planetary shadowing in shaping Jupiter's gossamer ring structure

    NASA Astrophysics Data System (ADS)

    Krueger, Harald; Hamilton, Douglas P.; Moissl, Richard; Gruen, Eberhard

    particle ring material interior to Thebe's orbit. The existence of this partially evacuated gap in ring is also indirectly confirmed by Galileo in-situ energetic particle measurements (Norbert Krupp, priv. comm.). Recent modelling (Hamilton & Kr¨ger, u Nature, submitted) shows that time variable electromagnetic effects can account for all of these surprising results. In particular, when the ring particles travel through Jupiter's shadow, dust grain electric charges vary systematically, driving grains out into the Thebe Extension and matching the Galileo in-situ dust measurements.

  17. A high-resolution spectral analysis of three carbon-enhanced metal-poor stars

    NASA Astrophysics Data System (ADS)

    Goswami, Aruna; Aoki, Wako; Beers, Timothy C.; Christlieb, Norbert; Norris, John E.; Ryan, Sean G.; Tsangarides, Stelios

    2006-10-01

    of Japan, and at HCT, IAO, Hanle, India. E-mail: aruna@iiap.res.in (AG); aoki.wako@nao.ac.jp (WA); beers@pa.msu.edu (TCB); norbert@astro.uu.se (NC); jen@mso.anu.edu.au (JEN); s.g.ryan@herts.ac.uk (SGR); s.tsangarides@open.ac.uk (ST)

  18. Current Events via Electronic Media: An Instructional Tool in a General Education Geology Course

    NASA Astrophysics Data System (ADS)

    Flood, T. P.

    2008-12-01

    St. Norbert College (SNC) is a liberal arts college in the Green Bay Metropolitan area with an enrollment of approximately 2100 students. All students are required to take one science course with a laboratory component as part of the general education program. Approximately 40% of all SNC students take introductory geology. Class size for this course is approximately 35 students. Each faculty member teaches one section per semester in a smart classroom A synthesis of current events via electronic media is an excellent pedagogical tool for the introductory geology course. An on-going informal survey of my introductory geology class indicates that between 75- 85% of all students in the class, mostly freshman and sophomores, do not follow the news on a regular basis in any format, i.e. print, internet, or television. Consequently, most are unaware of current scientific topics, events, trends, and relevancy. To address this issue, and develop a positive habit of the mind, a technique called In-the-News-Making-News (INMN) is employed. Each class period begins with a scientifically-related (mostly geology) online news article displayed on an overhead screen. The articles are drawn from a variety of sources that include international sites such as the BBC and CBC; national sites such as PBS, New York Times, and CNN; and local sites such as the Milwaukee Journal Sentinel and the Green Bay Press Gazette. After perusing the article, additional information is often acquired by "Google" to help supplement and clarify the original article. An interactive discussion follows. Topics that are typically covered include: global climate change, basic scientific and technological discoveries, paleontology/evolution, natural disasters, mineral/ energy/ water resources, funding for science, space exploration, and other. Ancillary areas that are often touched on in the conversation include ethics, politics, economics, philosophy, education, geography, culture, or other. INMN addresses

  19. A distributed control approach for power and energy management in a notional shipboard power system

    NASA Astrophysics Data System (ADS)

    Shen, Qunying

    The main goal of this thesis is to present a power control module (PCON) based approach for power and energy management and to examine its control capability in shipboard power system (SPS). The proposed control scheme is implemented in a notional medium voltage direct current (MVDC) integrated power system (IPS) for electric ship. To realize the control functions such as ship mode selection, generator launch schedule, blackout monitoring, and fault ride-through, a PCON based distributed power and energy management system (PEMS) is developed. The control scheme is proposed as two-layer hierarchical architecture with system level on the top as the supervisory control and zonal level on the bottom as the decentralized control, which is based on the zonal distribution characteristic of the notional MVDC IPS that was proposed as one of the approaches for Next Generation Integrated Power System (NGIPS) by Norbert Doerry. Several types of modules with different functionalities are used to derive the control scheme in detail for the notional MVDC IPS. Those modules include the power generation module (PGM) that controls the function of generators, the power conversion module (PCM) that controls the functions of DC/DC or DC/AC converters, etc. Among them, the power control module (PCON) plays a critical role in the PEMS. It is the core of the control process. PCONs in the PEMS interact with all the other modules, such as power propulsion module (PPM), energy storage module (ESM), load shedding module (LSHED), and human machine interface (HMI) to realize the control algorithm in PEMS. The proposed control scheme is implemented in real time using the real time digital simulator (RTDS) to verify its validity. To achieve this, a system level energy storage module (SESM) and a zonal level energy storage module (ZESM) are developed in RTDS to cooperate with PCONs to realize the control functionalities. In addition, a load shedding module which takes into account the reliability

  20. Astrometry and early astrophysics at Kuffner Observatory in the late 19th century

    NASA Astrophysics Data System (ADS)

    Habison, Peter

    The astronomer and mathematician Norbert Herz encouraged Moriz von Kuffner, owner of the beer brewery in Ottakring, to finance a private scientific observatory in the western parts of Vienna. In the years 1884-87 the Kuffner Observatory was built at the Gallitzinberg in Wien-Ottakring. It was an example of enlighted patronage and noted at the time for its rapid acquisition of new instruments and by increasing international recognition. It contained the largest heliometer in the world and the largest meridian circle in the Austrian-Hungarian Empire. Of the many scientists who worked here we mention Leo de Ball, Gustav Eberhard, Johannes Hartmann and we should not forget Karl Schwarzschild. Here in Vienna he published papers on celestial mechanics, measuring techniques, optics and his fundamental papers concerning photographic photometry, in particular the quantitative determination of the departure of the reciprocity law. The telescope and the associated camera with which he carried out his measurements are still in existence at the observatory. The observatory houses important astronomical instruments from the 19th century. All telescopes were made by Repsold und Söhne in Hamburg, and Steinheil in Munich. These two German companies were best renowned for quality and precision in high standard astronomical instruments. The Great Refractor (270/3500 mm) is still the third largest refractor in Austria. It was installed at the observatory in 1886 and was used together with the Schwarzschild Refractor for early astrophysical work including photography. It is this double refractor, where Schwarzschild carried out his measurements on photographic photometry. The Meridian Circle (132/1500 mm) was the largest meridian passage instrument of the Austro-Hungarian Empire. Today it is the largest meridian circle in Austria and still one of the largest in Europe. The telescope is equipped with one of the first impersonal micrometers of that time. First observations were carried

  1. A Galactic Fossil

    NASA Astrophysics Data System (ADS)

    2007-05-01

    How old are the oldest stars? Using ESO's VLT, astronomers recently measured the age of a star located in our Galaxy. The star, a real fossil, is found to be 13.2 billion years old, not very far from the 13.7 billion years age of the Universe. The star, HE 1523-0901, was clearly born at the dawn of time. "Surprisingly, it is very hard to pin down the age of a star", the lead author of the paper reporting the results, Anna Frebel, explains. "This requires measuring very precisely the abundance of the radioactive elements thorium or uranium, a feat only the largest telescopes such as ESO's VLT can achieve." ESO PR Photo 23a/07 ESO PR Photo 23a/07 The 'Cosmic Clock' This technique is analogous to the carbon-14 dating method that has been so successful in archaeology over time spans of up to a few tens of thousands of years. In astronomy, however, this technique must obviously be applied to vastly longer timescales. For the method to work well, the right choice of radioactive isotope is critical. Unlike other, stable elements that formed at the same time, the abundance of a radioactive (unstable) isotope decreases all the time. The faster the decay, the less there will be left of the radioactive isotope after a certain time, so the greater will be the abundance difference when compared to a stable isotope, and the more accurate is the resulting age. Yet, for the clock to remain useful, the radioactive element must not decay too fast - there must still be enough left of it to allow an accurate measurement, even after several billion years. "Actual age measurements are restricted to the very rare objects that display huge amounts of the radioactive elements thorium or uranium," says Norbert Christlieb, co-author of the report. ESO PR Photo 23b/07 ESO PR Photo 23b/07 Uranium Line in the Spectrum of an Old Star Large amounts of these elements have been found in the star HE 1523-0901, an old, relatively bright star that was discovered within the Hamburg/ESO survey [1]. The

  2. A Glimpse of the Young Milky Way

    NASA Astrophysics Data System (ADS)

    2002-10-01

    metal-deficient stars that is currently being carried out at Hamburger Sternwarte [4]. Over a period of more than 10 years, a large collection of photographic pictures of the southern sky were obtained with the ESO 1-m Schmidt Telescope, a wide-angle telescope at the La Silla observatory in Chile that has now been decommissioned. Thanks to a large glass prism in the front of the telescope, every object in the observed sky field - stars as well as galaxies - was imaged as a small spectrum, providing a first rough idea about its type and composition. The main aim of this "Hamburg/ESO survey" (with Dieter Reimers , Associate Director of the Hamburger Sternwarte, as Principal Investigator and Lutz Wisotzki , now at Astrophysikalisches Institut Potsdam, Germany, as Project Scientist) was to find quasars (particularly active centres of galaxies), a task that was accomplished most successfully, cf. e.g., ESO PR 10/97 and ESO PR 08/00 (Report F). A very welcome by-product of this survey has been a rich harvest of very metal-poor stars . This part of the project is led by Norbert Christlieb , also from the Hamburg Observatory, and now on sabbatical leave at the Research School of Astronomy and Astrophysics of the Australian National University (Canberra, Australia). Using fast computers and advanced pattern-recognition software to analyze the photographic exposures and thus to sift through millions of registered stellar spectra, about 8000 candidates for very metal-poor stars were found. These stars are now being scrutinized spectroscopically one-by-one with many medium-sized telescopes all over the world. Confirmed candidates are then observed with the largest telescopes in the world in order to obtain very detailed spectra (of high spectral resolution), which allow the astronomers to determine their chemical composition accurately. The very metal-deficient star HE 0107-5240 ESO PR Photo 25a/02 ESO PR Photo 25a/02 [Preview - JPEG: 400 x 458 pix - 86k [Normal - JPEG: 800 x 915

  3. Hubble refurbished and ready for release

    NASA Astrophysics Data System (ADS)

    1993-12-01

    ) tomorrow morning. The telescope's aperture door will open just prior to the release. ESA astronaut Claude Nicollier will operate the shuttle's robot arm during the deployment, as he has throughout the lengthy spacewalks and the retrieval of the telescope. This mission has seen more arm operations than any other. Milt Heflin, NASA's lead flight director for the mission, paid tribute to Nicollier at a news conference today. "Claude was magnificent arm driver" he said. "The arm was surgically put in place every time. Folks can be very proud of him". Endeavour is scheduled to return to Earth Monday 13 December.

  4. The surprising magnetic topology of τ Sco: fossil remnant or dynamo output?

    NASA Astrophysics Data System (ADS)

    Donati, J.-F.; Howarth, I. D.; Jardine, M. M.; Petit, P.; Catala, C.; Landstreet, J. D.; Bouret, J.-C.; Alecian, E.; Barnes, J. R.; Forveille, T.; Paletou, F.; Manset, N.

    2006-08-01

    conclude that its magnetic field is most probably a fossil remnant from the star formation stage. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Science de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii. E-mail: donati@ast.obs-mip.fr (J-FD); idh@star.ucl.ac.uk (IDH); mmj@st-andrews.ac.uk (MMJ); petit@ast.obs-mip.fr (PP); claude.catala@obspm.fr (CC); jlandstr@uwo.ca (JDL); jean-claude.bouret@oamp.fr (J-CB); evelyne.alecian@obspm.fr (EA); jrb3@st-andrews.ac.uk (JRB); forveill@cfht.hawaii.edu (TF); fpaletou@ast.obs-mip.fr (FP); manset@cfht.hawaii.edu (NM)

  5. Hubble Space Telescope Servicing begins.

    NASA Astrophysics Data System (ADS)

    1993-12-01

    The day's work began when astronauts Story Musgrave and Jeff Hoffman stepped out into the cargo bay at 9h41 pm CST, Saturday (4h41 am CET, Sunday). They immediately set to work replacing two gyroscope assemblies, known as the Rate Sensor Units, two associated electronics boxes, called Electronic Control Units, and eight electrical fuse plugs. The work was completed ahead of schedule, but the astronauts had trouble closing the doors of the compartment housing the gyros and took over an hour to get them shut. The astronauts also prepared equipment for the replacement of the solar arrays. "The feeling down here is one of great satisfaction for a tremendous job today" said spacecraft communicator Greg Harbaugh in mission control. "We are very proud of the work that you all did and we are very confident in the continued success of the mission. Everything is going great and tomorrow is going to be another great day". ESA astronaut Claude Nicollier played a vital role during the spacewalk moving the astronauts and their equipment around the cargo bay with the shuttle's robot arm. The Hubble Space Telescope servicing mission features more robot arm operations than any other shuttle flight. The telescope's left-hand solar array was rolled up successfully at 6h24 am CST (1h24 pm CET). The 11-tonne observatory was rotated 180 degrees on its turntable before commands were sent to retract the second array at 8h23 am CST (3h23 pm CET). The crew stopped the retraction when it appeared the system may have jammed. Mission control instructed the crew to jettison the array, a procedure that they have trained for. Tomorrow astronauts Kathy Thornton and Tom Akers will make a six-hour spacewalk to jettison the troublesome wing, store the other in the cargo bay, and install two new panels supplied by ESA. The second set of arrays feature thermal shields and a modified thermal compensation system to prevent the flexing that affected the first pair. The Hubble Space Telescope was plucked

  6. HST's 10th anniversary, ESA and Hubble : changing our vision

    NASA Astrophysics Data System (ADS)

    2000-04-01

    With the astronauts who took part in the most recent Servicing Mission (SM3A) in attendance, ESA is taking the opportunity to give a - first - complete overview of Europe's major contribution to the HST mission. It will also review the first ten years of operations and the outstanding results that have "changed our vision" of the cosmos. A new fully European outreach initiative - the "European Space Agency Hubble Information Centre" - will be presented and officially launched; it has been set up by ESA to provide information on Hubble from a European perspective. A public conference will take place in the afternoon to celebrate Hubble's achievements midway through its life. Ten years of outstanding performance Launched on 24 April 1990, Hubble is now midway through its operating life and it is considered one of the most successful space science missions ever. So far more than 10,000 scientific papers based on Hubble results have been published and European scientists have contributed to more than 25% of these. Not only has Hubble produced a rich harvest of scientific results, it has impressed the man in the street with its beautiful images of the sky. Thousands of headlines all over the world have given direct proof of the public's great interest in the mission - 'The deepest images ever', 'The sharpest view of the Universe', 'Measurements of the earliest galaxies' and many others, all reflecting Hubble's performance as a top-class observatory. The Servicing Missions that keep the observatory and its instruments in prime condition are one of the innovative ideas behind Hubble. Astronauts have serviced Hubble three times, and ESA astronauts have taken part in two of these missions. Claude Nicollier (CH) worked with American colleagues on the First Servicing Mission, when Hubble's initial optical problems were repaired. On the latest, Servicing Mission 3A, both Claude Nicollier and Jean-François Clervoy (F) were members of the crew. Over the next 10 years European

  7. STS-103 crew take part in CEIT in PHSF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test in the Payload Hazardous Servicing Facility, members of the STS-103 crew check out the top of the Flight Support System (FSS) for the mission, the repair and upgrade of the Hubble Space Telescope. The number one in the foreground refers to one of the berthing latches on the FSS. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  8. STS-103 crew pose in front of Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During Terminal Countdown Demonstration Test (TDCT) activities at Launch Pad 39B, the STS-103 crew pose in front of the flame trench, which is situated underneath the Mobile Launcher Platform holding Space Shuttle Discovery. Standing left to right are Mission Specialists Claude Nicollier of Switzerland, who is with the European Space Agency (ESA), C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Pilot Scott J. Kelly, Commander Curtis L. Brown Jr., and Mission Specialists Jean-Frangois Clervoy of France, also with ESA, and Steven L. Smith. One of the solid rocket boosters and the external tank that are attached to Discovery can be seen in the photo. The flame trench is made of concrete and refractory brick, and contains an orbiter flame deflector on one side and solid rocket booster flame deflector on the other. The deflectors protect the flame trench floor and pad surface from the intense heat of launch. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  9. Hα kinematics of the Spitzer Infrared Nearby Galaxies Survey - II

    NASA Astrophysics Data System (ADS)

    Dicaire, I.; Carignan, C.; Amram, P.; Hernandez, O.; Chemin, L.; Daigle, O.; de Denus-Baillargeon, M.-M.; Balkowski, C.; Boselli, A.; Fathi, K.; Kennicutt, R. C.

    2008-04-01

    This is the second part of an Hα kinematics follow-up survey of the Spitzer Infrared Nearby Galaxies Survey (SINGS) sample. The aim of this paper is to shed new light on the role of baryons and their kinematics and on the dark/luminous matter relation in the star-forming regions of galaxies, in relation with studies at other wavelengths. The data for 37 galaxies are presented. The observations were made using Fabry-Perot interferometry with the photon-counting camera FaNTOmM on four different telescopes, namely the Canada-France-Hawaii 3.6-m, the ESO La Silla 3.6-m, the William Herschel 4.2-m and the Observatoire du mont Mégantic 1.6-m telescopes. The velocity fields are computed using custom IDL routines designed for an optimal use of the data. The kinematical parameters and rotation curves are derived using the GIPSY software. It is shown that non-circular motions associated with galactic bars affect the kinematical parameters fitting and the velocity gradient of the rotation curves. This leads to incorrect determinations of the baryonic and dark matter distributions in the mass models derived from those rotation curves. Based on observations made with the ESO 3.60-m telescope at La Silla Observatories under programme ID 076.B-0859 and on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France and the University of Hawaii. E-mail: isabelle@astro.umontreal.ca (ID);claude.carignan@umontreal.ca (CC) ‡ Visiting Astronomer, Canada-France-Hawaii Telescope, operated by the National Research Council of Canada, the Centre National de la Recherche Scientifique de France and the University of Hawaii.

  10. STS-103 crew practice emergency egress in the slidewire basket

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the slidewire basket on Launch Pad 39B, STS-103 Mission Specialist C. Michael Foale (Ph.D.) gets ready to pull the lever, which will release the basket. With Foale are fellow crew members Mission Specialists Claude Nicollier of Switzerland and John M. Grunsfeld (Ph.D.). The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The STS-103 crew are taking part in Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The other crew members taking part are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, and Jean-Frangois Clervoy of France. Clervoy and Nicollier are with the European Space Agency. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  11. STS-103 crew practice emergency egress in the slidewire basket

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the slidewire basket on Launch Pad 39B, STS-103 Mission Specialist Steven L. Smith reaches for the lever that will release the basket. With Smith is fellow crew member Mission Specialist Jean-Frangois Clervoy of France. The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The STS-103 crew are taking part in Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  12. STS-103 crew exit O&C Building to head for launch pad

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Wearing their launch suits, the STS-103 crew exit the Operations and Checkout Building at KSC, heading for the Astrovan that will take them to Launch Pad 39B and more Terminal Countdown Demonstration Test (TCDT) actvities. In front (left to right) are Pilot Scott J. Kelly and Commander Curtis L. Brown Jr.; in the second row are Mission Specialists John M. Grunsfeld (Ph.D.) and Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA); in the third row are C. Michael Foale (Ph.D.) and Claude Nicollier of Switzerland, also with ESA; and at the rear is Mission Specialist Steven L. Smith. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  13. Forging the link between nuclear reactions and nuclear structure

    NASA Astrophysics Data System (ADS)

    Dickhoff, W. H.

    2016-06-01

    A review of the recent applications of the dispersive optical model (DOM) is presented. Emphasis is on the nonlocal implementation of the DOM that is capable of describing ground-state properties accurately when data like the nuclear charge density are available. The present understanding of the role of short- and long-range physics in determining proton properties near the Fermi energy for stable closed-shell nuclei has relied mostly on data from the (e, e' p) reaction. Hadronic tools to extract such spectroscopic information have been hampered by the lack of a consistent reaction description that provides unambiguous and undisputed results. The DOM, conceived by Claude Mahaux, provides a unified description of both elastic nucleon scattering and structure information related to single-particle properties below the Fermi energy. We have recently introduced a nonlocal dispersive optical potential for both the real and imaginary part. Nonlocal absorptive potentials yield equivalent elastic differential cross sections for 40Ca as compared to local ones but change the l-dependent absorption profile suggesting important consequences for the analysis of nuclear reactions. Below the Fermi energy, nonlocality is essential for an accurate representation of particle number and the nuclear charge density. Spectral properties implied by (e, e' p) and (p, 2p) reactions are correctly described, including the energy distribution of about 10% high-momentum protons obtained at Jefferson Lab. The nonlocal DOM allows a complete description of experimental data both above (up to 200 MeV) and below the Fermi energy in 40Ca. It is further demonstrated that elastic nucleon-nucleus scattering data constrain the spectral strength in the continuum of orbits that are nominally bound in the independent-particle model. Extension of this analysis to 48Ca allows a prediction of the neutron skin of this nucleus that is larger than most predictions made so far.

  14. Galileo and Music: A Family Affair

    NASA Astrophysics Data System (ADS)

    Fabris, D.

    2011-06-01

    According to Viviani, Galileo's first biographer, the scientist was an excellent keyboard and lute player. In turn Vincenzo Galilei, father of the illustrious scientist, had been one of the most influential music theorist of his age and also a great composer and virtuoso of the lute. Galileo and his brother Michelangelo, born in 1575, inherited Vincenzo's duel skills, both in theory and practical music: Galileo's correspondences show indeed his competence in the music and in the lute playing; Michelagnolo, after being educated in part in Galileo's house in Padua, transferred to Germany in Munich, where he became a court lute player. Nevertheless, Galileo helped for the rest of his life not only his brother but also his nephews, as documented in dozen of family letters quite important to establish the central role of the music in Galileo's everyday life, a fact almost ignored by most modern biographers. The importance of music in Galileo's output and life has been first outlined by the historian of sciences Stillman Drake and by the musicologist Claude Palisca. After their studies starting in the 1960s there is a great belief that Vincenzo influenced his son Galileo, directing him towards experimentation. The aim of this paper, following the reconstruction of Galileo's soundscape proposed by Pierluigi Petrobelli, is to reexamine the surviving historical accounts on the musical passion and talent of Galileo and his family in the several houses where they performed music (in Florence, Padua, Munich, etc.) in particular on the lute, the instrument that was an important experimental tool for the scientist.

  15. Ocean thermal energy conversion: Perspective and status

    NASA Astrophysics Data System (ADS)

    Thomas, Anthony; Hillis, David L.

    The use of the thermal gradient between the warm surface waters and the deep cold waters of tropical oceans was first proposed by J. A. d'Arsonval in 1881 and tried unsuccessfully by George Claude in 1930. Interest in Ocean Thermal Energy Conversion (OTEC) and other renewable energy sources revived in the 1970s as a result of oil embargoes. At that time, the emphasis was on large floating plants miles from shore producing 250 to 400 MW for maintained grids. When the problems of such plants became better understood and the price of oil reversed its upward trend, the emphasis shifted to smaller (10 MW) shore based plants on tropical islands. Such plants would be especially attractive if they produce fresh water as a by-product. During the past 15 years, major progress has been made in converting OTEC unknowns into knowns. Mini-OTEC proved the closed cycle concept. Cost effective heat exchanger concepts were identified. An effective biofouling control technique was discovered. Aluminum was determined to be promising for OTEC heat exchangers. Heat transfer augmentation techniques were identified, which promised a reduction on heat exchanger size and cost. Fresh water was produced by an OTEC open cycle flash evaporator, using the heat energy in the seawater itself. The current R and D emphasis is on the design and construction of a test facility to demonstrate the technical feasibility of the open cycle process. The 10 MW shore-based, closed cycle plant can be built with today's technology; with the incorporation of a flash evaporator, it will produce fresh water as well as electrical power; both valuable commodities on many tropical islands. The open cycle process has unknowns that require solution before the technical feasibility can be demonstrated. The economic viability of either cycle depends on reducing the capital costs of OTEC plants and on future trends in the costs of conventional energy sources.

  16. One of the origins of modernity and naturalism of French literature in the 19th century.

    PubMed

    Lee, Chan-Kyu; Lee, Na-Mi

    2013-04-01

    Authors studied how Claude Bernard, the first founder of experimental medicine, contributed significantly to establishment of modernism and influenced European modern culture. Authors first studied his views on modernity, comparing with Descartes and Magendie, and on the similarity between "Experimental medicine" and the European literature in the 19th century. Bernard was not exclusively against vitalism, but the dogmatic misuse of vitalism. His objective thinking could be a useful model for the authors, who considered science to be an origin of modernity in literature of naturalism. Especially, Emile Zola was strongly influenced by Bernard's "An introduction to the study of Experimental medicine" and published "Experimental novel," a manifesto of naturalism. Although Bernard's experimental methodology and determinism deeply influenced modern European culture, the relationship between his Experimental medicine and modernism have not been fully investigated yet. His experimental medicine also needs to be discussed from the ecological viewpoints. His anthropo-centrism was unique since he emphasized any human theory could not surpass the principle of nature. Conventional anthropo-centrism claims that human beings are superior enough to own and govern the nature. And Bernard's the necessary determinism contains the ecological principle that all life forms and inanimate objects are organically related and intertwined to each other, irrespectively of their usefulness for the human beings. Although there were some ethical debates related to his medical experiments on living bodies of animal, his strict principle to perform experiments only after animal or human body died was worth considering as an effort to sustain ecological viewpoints. He was also unique in terms of being realistic and candid about his situation which was limited by the 19th century's scientific and medical development. In conclusion, the significance of convergence of literature and medical science

  17. Multimedia Bootcamp: a health sciences library provides basic training to promote faculty technology integration

    PubMed Central

    Ramsey, Ellen C

    2006-01-01

    Background Recent research has shown a backlash against the enthusiastic promotion of technological solutions as replacements for traditional educational content delivery. Many institutions, including the University of Virginia, have committed staff and resources to supporting state-of-the-art, showpiece educational technology projects. However, the Claude Moore Health Sciences Library has taken the approach of helping Health Sciences faculty be more comfortable using technology in incremental ways for instruction and research presentations. In July 2004, to raise awareness of self-service multimedia resources for instructional and professional development needs, the Library conducted a "Multimedia Bootcamp" for nine Health Sciences faculty and fellows. Methods Case study. Results Program stewardship by a single Library faculty member contributed to the delivery of an integrated learning experience. The amount of time required to attend the sessions and complete homework was the maximum fellows had to devote to such pursuits. The benefit of introducing technology unfamiliar to most fellows allowed program instructors to start everyone at the same baseline while not appearing to pass judgment on the technology literacy skills of faculty. The combination of wrapping the program in the trappings of a fellowship and selecting fellows who could commit to a majority of scheduled sessions yielded strong commitment from participants as evidenced by high attendance and a 100% rate of assignment completion. Response rates to follow-up evaluation requests, as well as continued use of Media Studio resources and Library expertise for projects begun or conceived during Bootcamp, bode well for the long-term success of this program. Conclusion An incremental approach to integrating technology with current practices in instruction and presentation provided a supportive yet energizing environment for Health Sciences faculty. Keys to this program were its faculty focus, traditional

  18. Anatomist and the pioneer of radiology Étienne Destot--95th anniversary of his death.

    PubMed

    Báča, Václav; Kachlík, David; Báčová, Tereza; Bartoška, Radek; Marvan, Jiří; Douša, Pavel; Secrest, Thomas; Džupa, Valér

    2014-04-01

    Destot was a leading pioneer in radiology, a pupil of Ollier, an anatomist, and researcher who followed in the experimental medicine tradition of Claude Bérnard. This work is an extensive, in depth, look at the life and work of Étienne Destot. On February 5, 1896, he began performing X-ray examinations, less than two months after Roentgen's discovery! His pioneering work described a space bordered by the hamate, capitate, triquetrum, and lunate; this space is now known as Destot's space. Tanton stated that Destot was the first to reveal the mechanism of fractures of the posterior margin of the distal tibia and to emphasize their clinical relevance; in honor of this contribution, Tanton named such a fracture the “fracture of Destot.” Moreover, Destot is credited with being the first physician to use the term “pilon” in the orthopedic literature. He first described fractures of the scaphoid in 1905. He also described superficial hematomas, Destot's sign, located above the inguinal ligament or in the scrotum or thigh. Such hematomas are indicative of pelvic fractures. Destot is credited with inventing or improving many pieces of medical equipment (e.g., Lambotte's screw plates, anastomotic boutons for the digestive tube, monopolar endocavital radiological tubes). He was also active in developing technical aspects of equipment (e.g., radioscopic examination of the heart, a prototype of the mobile radiological laboratory). Étienne Destot is best known as a radiologist; however, his influence extends well beyond this field. He was an anatomist and surgeon, the founder of radiology in Lyon, prosector, physician, electrician, researcher, and artist. PMID:24772482

  19. Laboratory investigations of the response of Brewer-Mast ozonesondes to tropospheric ozone

    NASA Astrophysics Data System (ADS)

    Tarasick, David W.; Davies, Jonathan; Anlauf, Kurt; Watt, Maurice; Steinbrecht, Wolfgang; Claude, Hans J.

    2002-08-01

    The Brewer-Mast ozonesonde was used at Canadian stations from 1966 until 1980, when the Canadian network switched to the electrochemical concentration cell sonde. While the sondes appear to agree relatively well in the stratosphere, there is an evident discrepancy of 10-20% in tropospheric measurements [e.g., Tarasick et al., 1995, Figure 4]. Comparison of Brewer-Mast sondes with a calibrated ozone source yields some interesting insight into this discrepancy. Sonde response is strongly dependent on the preflight preparation procedures employed. Although sondes prepared via procedures introduced in the 1980s [Claude et al., 1987] perform quite well, when prepared according to the procedures used in Canada in the 1970s, Brewer-Mast sondes indicate 10-30% lower ozone than the calibrator. The following points are noted in particular: (1) a new Brewer-Mast sonde shows a large (~15%) increase in sensitivity between successive experiments; (2) especially at low (<100 ppb) O3 levels, the response even of previously flown sondes increases slowly with time; and (3) sondes show an additional slow increase of response with time that is apparently caused by ozone reactions with the phosphate buffer. The overall response curve indicated by 1, 2, and 3 implies that after correction to the observed total ozone, the earlier part of a flight would yield values that are too low, while the latter part would be too high. By applying a varying ozone input, simulating the typical variation in absolute ozone concentration experienced by a sonde in flight, we show that this can explain both the average correction factor (1.255) for the Canadian Brewer-Mast record and the 10-20% discrepancy in tropospheric measurements.

  20. STS-103 crew are interviewed by media at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Launch Pad 39B, Lisa Malone, chief, Media Services at KSC introduces the STS-103 crew standing ready to answer questions from the media. From left are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), and Claude Nicollier of Switzerland, who is also with ESA. As a preparation for launch, the crew have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  1. [The Vitruvian Man: an anatomical drawing for proportions by Leonardo Da Vinci].

    PubMed

    Le Floch-Prigent, P

    2008-12-01

    The aim of the study was to find out and to analyse the text by Vitruvius which inspired the famous drawing by Leonardo da Vinci (circa 1490) kept in the Galleria dell'Accademia, in Venezia, Italy: the man inscribed in one circle and in one square. The book "de Architectura" by Vitruvius Marcus Pollio was printed several times since the Renaissance when both the roman architecture of antiquity and this text became very popular. From a French translation by Claude Perrault in 1864, it became easy to find a French translation with the original text in Latin (Paris, 2003, Les Belles Lettres, French text by Pierre Gros). The drawing by Leonardo da Vinci illustrates with great accuracy and fidelity the quotation of Vitruvius (with the exception of two of the 12 main relationships). The genius of Leonardo da Vinci was to keep only one trunk, head and neck for two pairs of limbs: scapular and pelvic; to make the circle tangent to the lower edge of the square; to adjust a few features of the quotation for the equilibrium of the whole figure; and of course to bring his incredible skill as a drawer (one of the best of his century). The drawing was made on a sheet of paper 344x245mm, in black ink which became dark brown with time; several lines complete the figure above and below; a short caption and a horizontal scale appear just under the drawing. The celebrity of the drawing, a symbol of the Renaissance, of the equilibrium of man and mankind, of the universality of the artists and intellectuals of the time (Humanism) made it iconic and it has been constantly reproduced and adapted especially for advertisement and logos, not only in the medical field. PMID:18951824

  2. STS-103 crew is greeted after exiting the Crew Hatch Access Vehicle

    NASA Technical Reports Server (NTRS)

    1999-01-01

    As he exits the Crew Hatch Access Vehicle, STS-103 Commander Curtis L. Brown Jr. is greeted with a handshake by Joseph Rothenberg, associate administrator, Office of Space Flight. Descending the stairs behind Brown are (left to right) Mission Specialists C. Michael Foale (Ph.D.) and John M. Grunsfeld (Ph.D.) and Pilot Scott J. Kelly. At right, applauding the astronauts return are Earle Huckins, deputy associate administrator, Office of Space Science, and Roy Bridges, director, Kennedy Space Center. Others in the crew (not shown) are Mission Specialists Steven L. Smith, and Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency. The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  3. STS-103 crew take part in CEIT in OPF 1

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility (OPF) bay 1, STS-103 crew members check out equipment to be used on planned Extravehicular Activities (EVAs) on the mission for repair of the Hubble Space Telescope. They are taking part in a Crew Equipment Interface Test (CEIT) at KSC. From left are Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Steven L. Smith. Other crew members at KSC for the CEIT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  4. STS-103 Crew Training

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The Hubble Space Telescope (HST) team is preparing for NASA's third scheduled service call to Hubble. This mission, STS-103, will launch from Kennedy Space Center aboard the Space Shuttle Discovery. The seven flight crew members are Commander Curtis L. Brown, Pilot Scott J. Kelly, European Space Agency (ESA) astronaut Jean-Francois Clervoy who will join space walkers Steven L. Smith, C. Michael Foale, John M. Grunsfeld, and ESA astronaut Claude Nicollier. The objectives of the HST Third Servicing Mission (SM3A) are to replace the telescope's six gyroscopes, a Fine-Guidance Sensor, an S-Band Single Access Transmitter, a spare solid-state recorder and a high-voltage/temperature kit for protecting the batteries from overheating. In addition, the crew plans to install an advanced computer that is 20 times faster and has six times the memory of the current Hubble Space Telescope computer. To prepare for these extravehicular activities (EVAs), the SM3A astronauts participated in Crew Familiarization sessions with the actual SM3A flight hardware. During these sessions the crew spent long hours rehearsing their space walks in the Guidance Navigation Simulator and NBL (Neutral Buoyancy Laboratory). Using space gloves, flight Space Support Equipment (SSE), and Crew Aids and Tools (CATs), the astronauts trained with and verified flight orbital replacement unit (ORU) hardware. The crew worked with a number of trainers and simulators, such as the High Fidelity Mechanical Simulator, Guidance Navigation Simulator, System Engineering Simulator, the Aft Shroud Door Trainer, the Forward Shell/Light Shield Simulator, and the Support Systems Module Bay Doors Simulator. They also trained and verified the flight Orbital Replacement Unit Carrier (ORUC) and its ancillary hardware. Discovery's planned 10-day flight is scheduled to end with a night landing at Kennedy.

  5. STS-103 crew take part in CEIT in the orbiter Discovery

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the payload bay of the orbiter Discovery, STS-103 Mission Specialists John M. Grunsfeld (Ph.D.), left, and Claude Nicollier of Switzerland, right, are briefed on part of the equipment they will use on their mission by a worker from Johnson Space Center, center. The mission involves the repair and upgrade of the Hubble Space Telescope. The crew, who are at KSC to take part in a Crew Equipment Interface Test, also includes Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and Jean-Fran'''ois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS- 103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  6. Stephen Hales: the contributions of an Enlightenment physiologist to the study of the kidney in health and disease.

    PubMed

    Eknoyan, Garabed

    2016-02-01

    Stephen Hales (1677-1761) was an English clergyman who made major contributions to a wide range of scientific topics such as botany, chemistry, pneumatics, and physiology. Early in his career he developed a keen interest in medicine through his association with his younger physician friend at Cambridge, William Stukeley (1687-1765), with whom he dissected animals and attended experiments in the laboratory of Isaac Newton. His fame as a scientist grew and by the end of his life he had achieved an international reputation as a major scientist of the Enlightenment. He is best known for his 1733 Statical Essays, in the second part of which he describes his studies in animal physiology. Most famous amongst those are his assessments of the force of the blood, which he measured in horses and dogs. Less well known and often unrecognized are his studies on the kidney in health and disease, which are the focus of this review. Amongst others Hales described the effects of hemorrhagic shock which he observed as he bled his animals while measuring their blood pressure; he then studied the effect of increasing saline perfusion pressures on the renal secretion of urine; and delved into biochemistry in exploring the composition of and solutions to dissolve bladder stones. His 1733 statement in the introduction to his hemodynamic studies that the healthy State of the Animal principally consists, in the maintaining of a due Equilibrium between the body solids and fluids literally predicts the milieu intrieur that would ultimately be formulated in 1854 by Claude Bernard (1813-1878). PMID:26913873

  7. AGC1/2, the mitochondrial aspartate-glutamate carriers.

    PubMed

    Amoedo, N D; Punzi, G; Obre, E; Lacombe, D; De Grassi, A; Pierri, C L; Rossignol, R

    2016-10-01

    In this review we discuss the structure and functions of the aspartate/glutamate carriers (AGC1-aralar and AGC2-citrin). Those proteins supply the aspartate synthesized within mitochondrial matrix to the cytosol in exchange for glutamate and a proton. A structure of an AGC carrier is not available yet but comparative 3D models were proposed. Moreover, transport assays performed by using the recombinant AGC1 and AGC2, reconstituted into liposome vesicles, allowed to explore the kinetics of those carriers and to reveal their specific transport properties. AGCs participate to a wide range of cellular functions, as the control of mitochondrial respiration, calcium signaling and antioxydant defenses. AGC1 might also play peculiar tissue-specific functions, as it was found to participate to cell-to-cell metabolic symbiosis in the retina. On the other hand, AGC1 is involved in the glutamate-mediated excitotoxicity in neurons and AGC gene or protein alterations were discovered in rare human diseases. Accordingly, a mice model of AGC1 gene knock-out presented with growth delay and generalized tremor, with myelinisation defects. More recently, AGC was proposed to play a crucial role in tumor metabolism as observed from metabolomic studies showing that the asparate exported from the mitochondrion by AGC1 is employed in the regeneration of cytosolic glutathione. Therefore, given the central role of AGCs in cell metabolism and human pathology, drug screening are now being developed to identify pharmacological modulators of those carriers. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:27132995

  8. What do we do, if some of the MICE magnets can't be kept cold using the two-stage coolers?

    SciTech Connect

    Green, Michael A.

    2011-01-26

    Tests of the spectrometer solenoids have not been encouraging in terms of keeping the magnets cold using three 1.5 W (at 4.2 K) coolers. The spectrometer solenoids are being rebuilt with additional cooling capacity at 4.2 K. It is hoped that there will be sufficient 4.2 K cooling to keep the magnets cold. The spectrometer solenoids can be kept cold using liquid helium (up to a boil-off of 20 liters per day). This option does not apply for the other magnets in the MICE cooling channel, because there is not enough liquid helium storage within the magnet cold mass. It is important that the MICE collaboration ask the question, “How do we keep the MICE cooling channel magnets cold, if there isn’t sufficient cooling from the 4.2 K coolers?” This report discusses the cooling requirements at both 40 K and 4.2 K for all three types of MICE cooling channel magnets. This report discusses the steps that must be taken in the magnet fabrication to permit the magnets to be cooled using a small (20 to 40 W) external 4.2 K Claude cycle refrigerator. One must also ask the question as to whether there is enough excess capacity in the decay solenoid refrigerator to cool some of the MICE magnets. A plan for cooling the magnets using a Linde 1400 series refrigerator is presented. A plan for increasing the 4.4 K refrigeration from the existing decay solenoid refrigerator is also presented.

  9. [By way of a synthesis of its conceptual evolution towards scientific medicine].

    PubMed

    de Micheli-Serra, A

    1999-01-01

    A historic outline of the evolution of medical thought toward scientific medicine is presented. Galen from Pergamon, one of science's first philosophers, wrote an Institutio logica, which can be considered as an introduction to the scientific method. Later, the Nominalists of the XIV century, precursors of modern science, thought that science's object was not the general, vague and indeterminate, but the particular, which is real and can be known directly. About the middle of the XVII Century the bases of the modern science became established thanks to a revolution formented essentially by Galileo, Bacon and Descartes. During the XVIII Century, parallel to the development of the great current of English Empiricism, a movement of scientific renewal also arose in continental Europe following the discipline of the Dutch Physicians and of Boerhaave. In the last century, Claude Bernard dominated scientific medicine, but his rigorous determinism impeded him from taking into account the immense and unforeseeable field of the random. Nowadays, we approach natural science and medicine from particular groups of facts, that is, from the responses of Nature to specific questions, but not from general laws. Furthermore, in recent epistemology, the concept that experimental data are not pure facts, but rather, facts interpreted within a hermeneutical context has been established. Finally, a general tendency to retrieve philosophical questions concerning the understanding of essence and existence can frequently be seen in scientific inquiry. In the light of the evolution of medical thought, it is possible to establish the position of scientific medicine within the movement of ideas dominating in our time. PMID:10204312

  10. The short history of gastroenterology.

    PubMed

    Sródka, A

    2003-12-01

    In this paper research on the stomach and bowel physiology is presented in a historical perspective. The author tries to show how digestive processes were interpreted by the ancients and how they tried to adjust them to the dominating humoral theory of disease. It is pointed out that the breakthrough which created a new way of understanding of the function of the digestive system was made by Andreas Vesalius and his modern model of anatomy. The meaning of acceptance of chemical processes in digestion by iatrochemics representatives in XVII century is shown. Physiological research in XIX century, which decided about a rapid development of physiology, especially the physiology of the gastrointestinal tract, is discussed. Experiments were performed by all main representatives of this discipline: Claude Bernard, Jan Ewangelista Purkyne, Rudolph Heidenhain and especially Ivan Pavlov, who, thanks to the discoveries in the secretion physiology, explained basic functions of the central nervous system. The XX century was dominated by the research showing the important role of the endocrine system and biological agents in the regulation of secretion and motility of the digestive system. The following discoveries are discussed: Ernest Sterling (secretin), John Edkins (gastrin) and André Latarjet and Lester Dragstedt (acetylcholine). It is underlined that Polish scientists play an important role in the development of the gastroenterological science--among others, Walery Jaworski, who made a historical suggestion about the role of the spiral bacteria in etiopathogenesis of the peptic ulcer, Leon Popielski, who stated the stimulating influence of histamine on the stomach acid secretion, Julian Walawski, who discovered enterogastrons--hormones decreasing secretion. As a supplement, there is the list of achievements in the field of the physiology and pathology of the gastrointestinal tract awarded with Nobel Prize and the list of most important Polish papers in this field. PMID

  11. [From Nebuchadnezzar to the randomized controlled trial--milestones in the development of clinical research].

    PubMed

    Oberbaum, Menachem; Lysy, Joseph; Gropp, Cornelius

    2011-08-01

    The first clinical experiment is described in the bible: The prophet Daniel is reported being nourished during ten days by seeds and water only, in order to check if his physical state would deteriorate as a result of this minimal nutrition. In the 15th century, French surgeon Ambroise Parí experimented with a mixture of turpentine, egg protein and rose oil to treat combat wounds, which is thought to be the first clinical study to be reported. In the 19th century British scientist James Lind designed the first controlled prospective study with parallel groups, proving that ingesting citrus fruit prevents scurvy. A short time afterwards British scientist John Haygarth was the first to use a placebo drug in a clinical study. Important work on placebo was conducted by the American scientists Austin Flint and later by Henry K. Beecher, who showed that placebo itself has biological properties. The importance of comparative studies was first understood by French psychologist CLaude Bernard. He is considered the founder of the modern scientific method based on observation, analysis of data and examination of hypotheses. Bernard's work was based on the work of fellow Frenchman Pierre Charles Alexandre Louis, who is justly considered a founding father of modern epidemiology, and who was the first to use statistics in clinical experiments. Random distributions in clinical studies were reported even before this time, for instance in the work of the Flemish physician Johannes Baptista van Helmont. Danish Nobel prize winner Johannes Fibiger pioneered the use of selection bias in his work with diphtheria serum. PMID:21939122

  12. Chapter 40: history of neurology in France.

    PubMed

    Clarac, François; Boller, François

    2010-01-01

    The history of neurology in France is characterized by the very high degree of centralization in that country where "everything seems to happen in Paris," and yet the considerable degree of autonomous diversity in the evolution of some other medical schools such as Montpellier and Strasbourg. It could be argued that France saw the birth of clinical neurology as a separate discipline since Jean Martin Charcot at the Salpêtrière Hospital obtained a chair of diseases of the nervous system in 1892, a first in the history of the academic world. The chapter shows, however, that the work of Charcot was preceded by a long evolution in medical thinking, which culminated with the introduction of experimental medicine developed by Claude Bernard and François Magendie, and by the study of aphasia by Paul Broca and its localization of language in a specific area of the brain. Many of the great neurologists of France like Duchenne de Boulogne, Gilles de la Tourette, Joseph Babinski and Pierre Marie gravitated around Charcot while others like Charles-Edward Brown-Sequard and Jules Dejerine developed their talents independently. The history of Sainte-Anne Hospital further illustrates this independence. It also shows the relation between neurology and psychiatry with Henri Ey, Jean Delay and Pierre Deniker, who collaborated with Henri Laborit in the clinical development of chlorpromazine. Sainte Anne also saw the birth of modern neuropsychology with Henry Hécaen. Jean Talairach and his group developed human stereotaxic neurosurgery and a 3-dimensional brain atlas that is used around the world. The chapter also mentions institutions (the CNRS and INSERM) that have contributed to developments partially independently from medical schools. It concludes with a presentation of schools located outside of Paris that have played a significant role in the development of neurology. Six of the most important ones are described: Montpellier, Toulouse, Bordeaux, Strasbourg, Lyon, and

  13. Birth of modern psychiatry and the death of alienism: the legacy of Jean-Martin Charcot.

    PubMed

    Bogousslavsky, Julien; Moulin, Thierry

    2011-01-01

    At the time of Jean-Martin Charcot, Paris--the main center for studies on the nervous system and its disorders--was home to critical exchanges between the developing discipline of neurology and psychiatry. Contrary to the commonly held view, and in spite of an established tradition concerning mental diseases, emerging neurology had a much stronger influence on psychiatry ('alienism') than the reverse. This was largely due to the school built up by Jean-Martin Charcot himself, which was organized around the study and management of hysteria. Although Charcot always claimed to be uninterested in mental medicine, he stimulated the development of an original scientific approach to nervous system conditions, based on Claude Bernard's method, along with structured academic teaching. Conversely, alienism paradoxically remained stuck in organicism, after Antoine Bayle's report in 1822 of 'arachnitis' as the substratum of general paresis of the insane. Contrary to alienism, the young neurological school was capable of self-criticism, and progressively highlighted mental factors in hysteria. This led to the paradox that neurologists were active in a disease with no organic cerebral lesion, while alienists were postulating brain lesions in all mental disorders. Pushed by Charcot, the academic evolution led to the launch of a faculty chair of mental and brain diseases in 1875, which was taken over for nearly half a century by his direct pupils Benjamin Ball, Alix Joffroy and Gilbert Ballet, who held the position until 1916, supporting the development of modern psychiatry in general hospitals, while alienism progressively disappeared at the turn of the century. PMID:20938143

  14. Calcium regulation of mitochondrial carriers.

    PubMed

    Del Arco, Araceli; Contreras, Laura; Pardo, Beatriz; Satrustegui, Jorgina

    2016-10-01

    Mitochondrial function is regulated by calcium. In addition to the long known effects of matrix Ca(2+), regulation of metabolite transport by extramitochondrial Ca(2+) represents an alternative Ca(2+)-dependent mechanism to regulate mitochondrial function. The Ca(2+) regulated mitochondrial transporters (CaMCs) are well suited for that role, as they contain long N-terminal extensions harboring EF-hand Ca(2+) binding domains facing the intermembrane space. They fall in two groups, the aspartate/glutamate exchangers, AGCs, major components of the NADH malate aspartate shuttle (MAS) and urea cycle, and the ATP-Mg(2+)/Pi exchangers or short CaMCs (APCs or SCaMCs). The AGCs are activated by relatively low Ca(2+) levels only slightly higher than resting Ca(2+), whereas all SCaMCs studied so far require strong Ca(2+) signals, above micromolar, for activation. In addition, AGCs are not strictly Ca(2+) dependent, being active even in Ca(2+)-free conditions. Thus, AGCs are well suited to respond to small Ca(2+) signals and that do not reach mitochondria. In contrast, ATP-Mg(2+)/Pi carriers are inactive in Ca(2+) free conditions and activation requires Ca(2+) signals that will also activate the calcium uniporter (MCU). By changing the net content of adenine nucleotides of the matrix upon activation, SCaMCs regulate the activity of the permeability transition pore, and the Ca(2+) retention capacity of mitochondria (CRC), two functions synergizing with those of the MCU. The different Ca(2+) activation properties of the two CaMCs are discussed in relation to their newly obtained structures. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:27033520

  15. The transport mechanism of the mitochondrial ADP/ATP carrier.

    PubMed

    Kunji, Edmund R S; Aleksandrova, Antoniya; King, Martin S; Majd, Homa; Ashton, Valerie L; Cerson, Elizabeth; Springett, Roger; Kibalchenko, Mikhail; Tavoulari, Sotiria; Crichton, Paul G; Ruprecht, Jonathan J

    2016-10-01

    The mitochondrial ADP/ATP carrier imports ADP from the cytosol and exports ATP from the mitochondrial matrix, which are key transport steps for oxidative phosphorylation in eukaryotic organisms. The transport protein belongs to the mitochondrial carrier family, a large transporter family in the inner membrane of mitochondria. It is one of the best studied members of the family and serves as a paradigm for the molecular mechanism of mitochondrial carriers. Structurally, the carrier consists of three homologous domains, each composed of two transmembrane α-helices linked with a loop and short α-helix on the matrix side. The transporter cycles between a cytoplasmic and matrix state in which a central substrate binding site is alternately accessible to these compartments for binding of ADP or ATP. On both the cytoplasmic and matrix side of the carrier are networks consisting of three salt bridges each. In the cytoplasmic state, the matrix salt bridge network is formed and the cytoplasmic network is disrupted, opening the central substrate binding site to the intermembrane space and cytosol, whereas the converse occurs in the matrix state. In the transport cycle, tighter substrate binding in the intermediate states allows the interconversion of conformations by lowering the energy barrier for disruption and formation of these networks, opening and closing the carrier to either side of the membrane in an alternating way. Conversion between cytoplasmic and matrix states might require the simultaneous rotation of three domains around a central translocation pathway, constituting a unique mechanism among transport proteins. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:27001633

  16. STS-103 crew learn about use of slideware basket at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the slidewire area of Launch Pad 39B, the STS-103 crew listen to use of the emergency egress equipment. From left are the trainer, with crew members Mission Specialists Steven L. Smith, Jean-Frangois Clervoy of France, Claude Nicollier of Switzerland, John M. Grunsfeld (Ph.D.), Pilot Steven J. Kelly, C. Michael Foale (Ph.D.), and (kneeling) Commander Curtis L. Brown Jr. Clervoy and Nicollier are both with the European Space Agency. As a preparation for launch, the crew have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  17. Glutamine transporters in mammalian cells and their functions in physiology and cancer.

    PubMed

    Bhutia, Yangzom D; Ganapathy, Vadivel

    2016-10-01

    The SLC (solute carrier)-type transporters (~400 in number) in mammalian cells consist of 52 distinct gene families, grouped solely based on the amino acid sequence (primary structure) of the transporter proteins and not on their transport function. Among them are the transporters for amino acids. Fourteen of them, capable of transporting glutamine across the plasma membrane, are found in four families: SLC1, SLC6, SLC7, and SLC38. However, it is generally thought that the members of the SLC38 family are the principal transporters for glutamine. Some of the glutamine transporters are obligatory exchangers whereas some function as active transporters in one direction. While most glutamine transporters mediate the influx of the amino acid into cells, some actually mediate the efflux of the amino acid out of the cells. Glutamine transporters play important roles in a variety of tissues, including the liver, brain, kidney, and placenta, as clearly evident from the biological and biochemical phenotypes resulting from the deletion of specific glutamine transporters in mice. Owing to the obligatory role of glutamine in growth and proliferation of tumor cells, there is increasing attention on glutamine transporters in cancer biology as potential drug targets for cancer treatment. Selective blockers of certain glutamine transporters might be effective in preventing the entry of glutamine and other important amino acids into tumor cells, thus essentially starving these cells to death. This could represent the beginning of a new era in the discovery of novel anticancer drugs with a previously unexplored mode of action. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. PMID:26724577

  18. Carnitine transport and fatty acid oxidation.

    PubMed

    Longo, Nicola; Frigeni, Marta; Pasquali, Marzia

    2016-10-01

    and Jean-Claude Martinou. PMID:26828774

  19. An evolution in student-centered teaching.

    PubMed

    Goodman, Barbara E

    2016-09-01

    The American Physiological Society (APS) Teaching Section annually honors an educator through its Claude Bernard Distinguished Lecture at the Experimental Biology meeting. Since I knew about my selection for almost a year, I had a long time to think about what I wanted to say and how I wanted to say it. The theme of my presentation was "nothing in education makes sense except in the light of student learning." My presentation began with a video of my "And, But, Therefore" description of my educational scholarship (see Randy Olson Great Challenges Day at TEDMED 2013, Ref. 10). "Physiology is the basic foundation of all the health professions AND physiology can be hard for students to figure out BUT many physiology courses expect students to memorize a large number of facts; THEREFORE, my scholarship is to help students learn physiology better for the long-term with various types of student-centered learning opportunities." To stress the goal of student-centered learning, my brief video was followed by a 2-min video of one of my students describing her experiences with student-centered learning in one of my two-semester Advanced Human Physiology classes. Since I have been convinced that Randy Olson is an expert on science communication (11), the rest of my presentation was the story about how I have evolved from a sage-on-the-stage lecturer into a student-centered learning facilitator. I have chosen Olson's "And, But, Therefore" approach to narrative for this written version of key aspects of the presentation. PMID:27445274

  20. Le Laboratoire de Mécanique Appliquée Raymond Chaléat a 40 ans !

    NASA Astrophysics Data System (ADS)

    Comité D'Organisation Du Colloque Ime 2002, Le

    2002-12-01

    Le LMARC a été créé par Raymond Chaléat dans les locaux de l'École Nationale d'Horlogerie (a présent Lycée Technique Jules Haag).L'équipe de recherche était alors constituée de 2 enseignants-chercheurs (Raymond Chaléat et Gérard Lallement) et d'un technicien (Bernard Prêtre). Les travaux de recherche se situaient naturellement dans le domaine de la chronométrie et en particulier dans la mécanique non linéaire analytique inhérente à la montre en fonctionnement. En effet, Raymond Chaléat fut l'élève, puis le collaborateur du Professeur Jules Haag, mathématicien et mécanicien, lui-même élève de Poincarré.Le LMARC a étendu ses activités avec l'arrivée de Claude Oudet, puis de Claude Oytana à la rhéologie des matériaux solides qui est devenue plus tard l'Équipe Propriétés Mécaniques des Matériaux. En parallèle, G. Lallement a créé une équipe Vibrations devenue à ce jour Dynamique des Structures. À ce jour, le Laboratoire compte plus de 110 personnes dont 40 doctorants.Il a depuis diversifié ses activités avec 3 nouvelles équipes tournées vers la Modélisation et la Mise en Forme des Matériaux, les Micromachines et la Biomécanique et les Mécanismes. Il a su également prendre toute sa place au sein de l'Institut des Microtechniques de Franche-Comté en contribuant à plusieurs thèmes.Notre Laboratoire a été l'un des premiers laboratoires associé au CNRS (4ème) et a toujours été rattaché à l'Université de Franche-Comté (Présidence par C. Oytana de 1996 a 2001) par l'entremise de I'UFR Sciences et Techniques. Il a toujours maintenu des liens forts avec I'ENSMM (École Nationale Supérieure de Mécanique et des Microtechniques) d'une part par ses enseignants-chercheurs et d'autre part deux de ses directeurs, Raymond Chaléat et actuellement Jean-Claude Gelin.En plus de ses relations constantes avec l'industrie régionale, le LMARC a développé des actions contractuelles avec de grands groupes tels que EDF

  1. PREFACE: Loops 11: Non-Perturbative / Background Independent Quantum Gravity

    NASA Astrophysics Data System (ADS)

    Mena Marugán, Guillermo A.; Barbero G, J. Fernando; Garay, Luis J.; Villaseñor, Eduardo J. S.; Olmedo, Javier

    2012-05-01

    only was it a showroom for the research currently being carried out by many groups throughout the world, but there was also a permanent look towards the future. During these days, the CSIC Campus witnessed many scientific conversations triggered by the interaction amongst the people and groups that participated in LOOPS'11 Madrid and which, in many cases, will crystallise into new results and advances in the field. The conference would not have been possible without the generous help of a number of national and international institutions. The organizers would like to acknowledge the financial support provided by the Spanish Ministry of Science and Innovation (Ministerio de Ciencia e Innovación), the Spanish Research Council, CSIC (Consejo Superior de Investigaciones Cientĺficas), The BBVA Foundation (Fundación BBVA), The CONSOLIDER-CPAN project, the Spanish Society for Gravitation and Relativity (SEGRE), The Universidad Carlos III of Madrid (UC3M), and the European Science Foundation (ESF). The ESF, through the Quantum Gravity and Quantum Geometry network, provided full support for a number of young participants that have contributed to these proceedings: Dario Benedetti (Albert Einstein Institute, Potsdam, Germany), Norbert Bodendorfer (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Mariam Bouhmadi López (CENTRA, Centro Multidisciplinar de Astrofĺsica, Lisbon), Timothy Budd (Institute for Theoretical Physics, Utrecht University, The Netherlands), Miguel Campiglia (Institute for Gravitation and the Cosmos, Penn State University, USA), Gianluca Delfino (School of Mathematical Sciences, University of Nottingham, UK), Maite Dupuis (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Michał Dziendzikowski (Institute of Theoretical Physics, Warsaw University, Poland), Muxin Han (Centre de Physique Théorique de Luminy, Marseille, France), Philipp Höhn (Institute for Theoretical Physics, Utrecht University, The

  2. IN MEMORIAM: Hermann Anton Haus, 1925 2003

    NASA Astrophysics Data System (ADS)

    2004-08-01

    Photograph Hermann Anton Haus, an Institute Professor at the Massachusetts Institute of Technology (MIT), was to have been a Keynote Speaker at the Fluctuations and Noise in Photonics and Quantum Optics Conference, from which the papers in this special issue derive. Sadly, on May 21, 2003 - less than two weeks before the conference - Professor Haus succumbed to a heart attack after arriving home in Lexington, Massachusetts, from his regular, 15-mile commute by bicycle from MIT. He was 77. Throughout his lengthy and illustrious career, Professor Haus had repeatedly and very successfully addressed problems of fluctuations and noise, with special focus on the fundamental issues that arise in quantum optics. To honour Professor Haus' legacy to our technical community, this special issue of Journal of Optics B: Quantum and Semiclassical Optics is dedicated to his memory. Professor Haus was born in Ljubljana, Slovenia, in the former Yugoslavia, on 8 August 1925. After attending the Technische Hochschule, Graz, and the Technische Hochschule, Wien, in Austria, he received his Bachelor of Science degree from Union College in Schenectady, New York in 1949. In 1951, he graduated from Rensselaer Polytechnic Institute with a Master of Science in Electrical Engineering, and came to MIT, where he earned his Doctorate of Science and joined the faculty in 1954. He was promoted to Associate Professor in 1958, to Professor in 1962, and to Elihu Thomson Professor in 1973. In 1986, he was conferred the honour of Institute Professor. Professor Haus had a lifelong fascination with noise. While still an undergraduate at Union College, he became aware of Norbert Wiener's theories of statistical phenomena - the new mathematics needed to understand and quantify the random fluctuations we refer to as noise. So it was that noise theory formed the core of Professor Haus' research during the 1950s: noise in electron beams, noise in microwave amplifiers, and noise in amplifier cascades. Two of

  3. Argonne National Laboratory summary site environmental report for calendar year 2006.

    SciTech Connect

    Golchert, N. W.; ESH /QA Oversight

    2008-03-27

    This booklet is designed to inform the public about what Argonne National Laboratory is doing to monitor its environment and to protect its employees and neighbors from any adverse environmental impacts from Argonne research. The Downers Grove South Biology II class was selected to write this booklet, which summarizes Argonne's environmental monitoring programs for 2006. Writing this booklet also satisfies the Illinois State Education Standard, which requires that students need to know and apply scientific concepts to graduate from high school. This project not only provides information to the public, it will help students become better learners. The Biology II class was assigned to condense Argonne's 300-page, highly technical Site Environmental Report into a 16-page plain-English booklet. The site assessment relates to the class because the primary focus of the Biology II class is ecology and the environment. Students developed better learning skills by working together cooperatively, writing and researching more effectively. Students used the Argonne Site Environmental Report, the Internet, text books and information from Argonne scientists to help with their research on their topics. The topics covered in this booklet are the history of Argonne, groundwater, habitat management, air quality, Argonne research, Argonne's environmental non-radiological program, radiation, and compliance. The students first had to read and discuss the Site Environmental Report and then assign topics to focus on. Dr. Norbert Golchert and Mr. David Baurac, both from Argonne, came into the class to help teach the topics more in depth. The class then prepared drafts and wrote a final copy. Ashley Vizek, a student in the Biology class stated, 'I reviewed my material and read it over and over. I then took time to plan my paper out and think about what I wanted to write about, put it into foundation questions and started to write my paper. I rewrote and revised so I think the amount of

  4. How Much Mass Makes a Black Hole? - Astronomers Challenge Current Theories

    NASA Astrophysics Data System (ADS)

    2010-08-01

    exploded and left a magnetar remnant must have had a shorter life than the surviving stars in the cluster. "Because the lifespan of a star is directly linked to its mass - the heavier a star, the shorter its life - if we can measure the mass of any one surviving star, we know for sure that the shorter-lived star that became the magnetar must have been even more massive," says co-author and team leader Simon Clark. "This is of great significance since there is no accepted theory for how such extremely magnetic objects are formed." The astronomers therefore studied the stars that belong to the eclipsing double system W13 in Westerlund 1 using the fact that, in such a system, masses can be directly determined from the motions of the stars. By comparison with these stars, they found that the star that became the magnetar must have been at least 40 times the mass of the Sun. This proves for the first time that magnetars can evolve from stars so massive we would normally expect them to form black holes. The previous assumption was that stars with initial masses between about 10 and 25 solar masses would form neutron stars and those above 25 solar masses would produce black holes. "These stars must get rid of more than nine tenths of their mass before exploding as a supernova, or they would otherwise have created a black hole instead," says co-author Ignacio Negueruela. "Such huge mass losses before the explosion present great challenges to current theories of stellar evolution." "This therefore raises the thorny question of just how massive a star has to be to collapse to form a black hole if stars over 40 times as heavy as our Sun cannot manage this feat," concludes co-author Norbert Langer. The formation mechanism preferred by the astronomers postulates that the star that became the magnetar - the progenitor - was born with a stellar companion. As both stars evolved they would begin to interact, with energy derived from their orbital motion expended in ejecting the requisite

  5. Surgery of the head and 70-day brain surgeons.

    PubMed

    Hanigan, William C

    2003-09-01

    In 1917, the Sugeon General of the United States Army, William Gorgas, learned that almost 15% of the casualties on the Western Front sustained intracranial injuries. Soon after the United States declared war in April 1917, the Council of National Defense established a General Medical Board and attached a brain surgery subsection to its Committee of Ophthalmology. Postcards were sent to experts around the country, asking for the names of individuals who had specialty training or practice in brain surgery. In August, Gorgas assumed control of this subsection and created a Division of Surgery of the Head in the American Army Medical Department, with additional sections for plastic surgery, ophthalmology, and otolaryngology. He needed almost 300 brain surgeons; he received 50 names. As Harvey Cushing, Gilbert Horrax, and others went to France, neurosurgeons at home trained student officers. Schools were established in Philadelphia (Charles Frazier), Chicago (Dean Lewis), New York City (Charles Elsberg), St. Louis (Ernest Sachs), and Camp Greenleaf in Georgia (Claude Coleman), with 10-week intensive courses for selected candidates. Basic science and x-ray classes and operative clinics addressed most aspects of neurosurgical care. An army manual outlined clinical diagnoses and surgical techniques. Lewis H. Weed established a laboratory at Johns Hopkins Hospital, staffed by volunteers such as K.D. Blackfan and W.E. Dandy, to investigate infections of the central nervous system. By the time of the armistice, Gorgas had his complement of brain surgeons. The newly trained brain surgeons and their mentors gradually made their way to the Western Front during the summer of 1918. Plans for a neurosurgical school in France were quickly discarded as the American Army Medical Department changed the specialized assignments to front-line general surgical care. Some of the 190 brain surgeons in the American Expeditionary Forces, notably Gilbert Horrax, Charles E. Dowman, and Charles

  6. SIMMAX: A modern analog technique to deduce Atlantic sea surface temperatures from planktonic foraminifera in deep-sea sediments

    NASA Astrophysics Data System (ADS)

    Pflaumann, Uwe; Duprat, Josette; Pujol, Claude; Labeyrie, Laurent D.

    1996-02-01

    leave the system.) (Paper 95PA01743,SIMMAX: A modern analog technique to deduce Atlantic sea surfacetemperatures from planktonic foraminifera in deep-sea sediments, UwePflaumann, Josette Duprat, Claude Pujol, and Laurent D. Labeyrie).Diskette may be ordered from American Geophysical Union, 2000Florida Avenue, N.W., Washington, DC 20009; Payment mustaccompany order.

  7. Crew of Hubble Space Telescope servicing mission visits Europe

    NASA Astrophysics Data System (ADS)

    1994-01-01

    The Hubble Space telescope servicing mission in December (STS-61) was a great success and the fully refurbished orbiting telescope produced absolutely remarkable first results just two weeks ago. The 7-member crew who carried out the mission will soon be in Europe to share their experience with the Press, ESA space specialists and the European space community. Public conferences will also be held in Switzerland, the home country of ESA astronaut Claude Nicollier. The visit of the STS-61 crew is scheduled as follows: Friday 11 February, 1994 - ESA Paris, France Presentation and Press Conference Location: ESA, 8/10 Rue Mario Nikis, 75015 Paris time: 16:00 hrs - 17:30 hrs contact: ESA, Public Relations Office Tel. (+33) 1 42 73 71 55 Fax. (+33) 1 42 73 76 90 Monday 14 February, 1994 - British Aerospace, Bristol, United Kingdom Presentation and Press Conference Location: British Aerospace, FPC 333, Filton, Bristol BS12 7QW time: 10:00 hrs - 12:00 hrs contact: BAe, Public Relations Tel. (+44) 272 36 33 69 Tel. (+44) 272 36 33 68 Tuesday 15 February, 1994 - ESA/ESTEC, Noordwijk, the Netherlands Presentation and Press Conference Location: Noordwijk Space Expo, Keplerlaan 3, 2201 AZ Noordwijk, the Netherlands time: 09:30 hrs - 12:00 hrs contact: ESTEC Public Relations Office Tel. (+31) 1719 8 3006 Fax. (+31) 1719 17 400 Wednesday 16 February, 1944 - ESO, Garching - Munich, Germany Presentation and Press Conference Location: European Southern Observatory, Karl- Schwarzschild-Str. 2, 85748 Garching -Munich, Germany time: to be decided contact: ESO Information Service Tel. (+49) 89 32 006 276 Fax. (+49) 89 320 23 62 Thursday 17 February, 1994 - Bern, Switzerland a. Presentation and Press Conference Location: Hotel Bern, Zeughausgasse 9, 3001 Bern, Switzerland time: 09:30 hrs contact: Press & Information Service of the Federal Dept. for Education & Sciences Tel. (+41) 31 322 80 34 Fax. (+41) 31 312 30 15 b. Public conference Location: University of Bern, Institute of Physics

  8. The MIT Program, Competition, and Ethics

    NASA Astrophysics Data System (ADS)

    Bradt, Hale V.

    2013-01-01

    The MIT program in x-ray astronomy was, and still is, diverse and productive. Bruno Rossi and later George Clark, as the nominal leaders of the “x-ray astronomy group” created a “hands-off” culture wherein individual researchers could develop their own independent programs. Walter Lewin, Claude Canizares, and I as well as those in the next academic generations, e.g., Saul Rappaport and George Ricker, were able to thrive in this environment. MIT researchers were principal investigators or providers of x-ray instruments on sounding rockets and balloons in the 1960s and then in later years on nine satellite missions, OSO-7, SAS-3, HEAO-1, Einstein, ASCA, RXTE, Chandra, HETE-2, and Suzaku. Such a diverse program involved collaborations with other institutions and of course striving for primacy in discovery and competition for NASA resources. Looking back, I see a high degree of ethical behavior among the observational x-ray community during those years. In competition, we remembered that we might well be collaborating the following year and behaved accordingly. Many of us in the x-ray community had been friends since graduate school days and did not want to lose those relationships. Am I viewing the past through rose colored glasses? I think not. A vignette on this topic: In 1967, I was debating vigorously with Herb Gursky of AS&E about which institution, MIT or AS&E, should be the lead on the fourth paper (Oda et al. 1967, ApJ 148, L5) based on data from the 1966 AS&E rocket flight which had led to Allan Sandage’s (and Japanese) identification of Sco X-1 (Sandage, et al. 1966, ApJ. 146, 316). I and my Italian colleague, Gianfranco Spada, and our Japanese colleague, Minoru Oda, both then visiting MIT, had actively supported that flight. After one rather heated discussion with Herb about this, - I was the heated one; he always remained calm - he left my office saying: “Hale, however this comes out, let’s remain friends.” I treasured that comment and

  9. Listening to the Shepard-Risset Glissando: the Relationship between Emotional Response, Disruption of Equilibrium, and Personality

    PubMed Central

    Vernooij, Eveline; Orcalli, Angelo; Fabbro, Franco; Crescentini, Cristiano

    2016-01-01

    The endless scale illusion, obtained by cyclically repeating a chromatic scale made up of Shepard tones, has been used in a variety of musical works. Music psychology and neuroscience has been interested in this particular psychoacoustic phenomenon mainly for studying the cognitive processes of pitch perception involved. In the present study, we investigated the emotional states induced by the Shepard-Risset glissando, a variant of the Shepard scale. For this purpose we chose three musical stimuli: a Matlab-generated Shepard Risset glissando, Jean-Claude Risset's Computer Suite from Little Boy, which presents a Shepard-Risset glissando integrated in the aesthetic context of a composition, and an ordinary orchestral glissando taken from the opening of Iannis Xenakis's Metastasis. Seventy-three volunteers completed a listening experiment during which they rated their emotional response to these stimuli on a seven-point Likert scale and indicated whether they had experienced a disruption of equilibrium. Personality was also measured with the Five-Factor Model of personality traits. The results show that negative emotions were most strongly evoked during listening to each of the stimuli. We also found that the Shepard-Risset glissando illusion, both within the aesthetic context of a musical composition and on its own, was capable of evoking disruption of equilibrium, frequently leading to the associated feeling of falling. Moreover, generally for the Shepard-Risset glissando illusion, higher negative emotional ratings were given by individuals who had experienced a feeling of disturbance of equilibrium relative to those who had not had this experience. Finally, we found a complex pattern of relationships between personality and the subjective experience of the glissando. Openness to experience correlated positively with positive emotion ratings for the Computer Suite, while agreeableness correlated negatively with positive emotion ratings for the Matlab stimulus

  10. Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment

    PubMed Central

    Foroulis, Christophoros N.; Darwiche, Kaid; Katsikogiannis, Nikolaos; Machairiotis, Nikolaos; Karapantzos, Ilias; Tsakiridis, Kosmas; Huang, Haidong; Zarogoulidis, Konstantinos

    2013-01-01

    Pancoast tumors account for less than 5% of all bronchogenic carcinomas. These tumors are located in the apex of the lung and involve through tissue contiguity the apical chest wall and/or the structures of the thoracic inlet. The tumors become clinically evident with the characteristic symptoms of the “Pancoast-Tobias syndrome” which includes Claude-Bernard-Horner syndrome, severe pain in the shoulder radiating toward the axilla and/or scapula and along the ulnar distribution of the upper arm, atrophy of hand and arm muscles and obstruction of the subclavian vein resulting in edema of the upper arm. The diagnosis will be made by the combination of the characteristic clinical symptoms with the radiographic findings of a mass or opacity in the apex of the lung infiltrating the 1st and/or 2nd ribs. A tissue diagnosis of the tumor via CT-guided FNA/B should always be available before the initiation of treatment. Bronchoscopy, thoracoscopy and biopsy of palpable supraclavicular nodes are alternative ways to obtain a tissue diagnosis. Adenocarcinomas account for 2/3 of all Pancoast tumors, while the rest of the tumors are squamous cell and large cell carcinomas. Magnetic resonance imaging of the thoracic inlet is always recommended to define the exact extent of tumor invasion within the thoracic inlet before surgical intervention. Pancoast tumors are by definition T3 or T4 tumors. Induction chemo-radiotherapy is the standard of care for any potentially resectable Pancoast tumor followed by an attempt to achieve a complete tumor resection. Resection can be made through a variety of anterior and posterior approaches to the thoracic inlet. The choice of the approach depends on the location of the tumor (posterior - middle - anterior compartment of the thoracic inlet) and the depth/extent of invasion. Prognosis depends mainly on T stage of tumor, response to preoperative chemo-radiotherapy and completeness of resection. Resection of the invaded strictures of the

  11. Listening to the Shepard-Risset Glissando: the Relationship between Emotional Response, Disruption of Equilibrium, and Personality.

    PubMed

    Vernooij, Eveline; Orcalli, Angelo; Fabbro, Franco; Crescentini, Cristiano

    2016-01-01

    The endless scale illusion, obtained by cyclically repeating a chromatic scale made up of Shepard tones, has been used in a variety of musical works. Music psychology and neuroscience has been interested in this particular psychoacoustic phenomenon mainly for studying the cognitive processes of pitch perception involved. In the present study, we investigated the emotional states induced by the Shepard-Risset glissando, a variant of the Shepard scale. For this purpose we chose three musical stimuli: a Matlab-generated Shepard Risset glissando, Jean-Claude Risset's Computer Suite from Little Boy, which presents a Shepard-Risset glissando integrated in the aesthetic context of a composition, and an ordinary orchestral glissando taken from the opening of Iannis Xenakis's Metastasis. Seventy-three volunteers completed a listening experiment during which they rated their emotional response to these stimuli on a seven-point Likert scale and indicated whether they had experienced a disruption of equilibrium. Personality was also measured with the Five-Factor Model of personality traits. The results show that negative emotions were most strongly evoked during listening to each of the stimuli. We also found that the Shepard-Risset glissando illusion, both within the aesthetic context of a musical composition and on its own, was capable of evoking disruption of equilibrium, frequently leading to the associated feeling of falling. Moreover, generally for the Shepard-Risset glissando illusion, higher negative emotional ratings were given by individuals who had experienced a feeling of disturbance of equilibrium relative to those who had not had this experience. Finally, we found a complex pattern of relationships between personality and the subjective experience of the glissando. Openness to experience correlated positively with positive emotion ratings for the Computer Suite, while agreeableness correlated negatively with positive emotion ratings for the Matlab stimulus

  12. Endeavour blasts-off on ambitious mission

    NASA Astrophysics Data System (ADS)

    1993-12-01

    "I am delighted to see the servicing mission off to such a beautiful start", said Roger Bonnet, ESA's Director of Science, who watched the launch from the Kennedy Space Center, Florida. "We are anxious to see the Hubble Space Telescope restored to its full capability so astronomers world- wide can take advantage of this unique observatory". During the eight and a half minute climb to orbit ESA astronaut Claude Nicollier helped the shuttle commander and pilot monitor the cockpit displays. Nicollier is the first international astronaut to serve as a shuttle's flight engineer. He will perform the same task at the end of the mission for reentry and landing. The European Space Agency has a major role in the telescope servicing mission. In addition to the presence of its astronaut, the agency is supplying new, improved power generating solar arrays and helped NASA test the Costar system of corrective optics. Nicollier will be responsible for operation of the shuttle's robot arm during the 11-day mission. He will use the arm to pluck the telescope from orbit and move astronauts and equipment around the payload bay during the mission's five spacewalks. The astronauts are spending their first hours in space setting up equipment in the orbiter's crew cabin. They will fire the shuttle's manoeuvring jets before going to bed to begin the two-day pursuit of the orbiting telescope. There will be three orbital manoeuvres tomorrow to further close the gap. The shuttle is due to reach the telescope Saturday and repair work will begin Sunday. Checkouts of the four space suits and the robot arm will occupy the crew tomorrow. Nicollier will use the arm to inspect the equipment in the cargo bay and later practise the manoeuvre he will use on Saturday to capture the telescope. Hubble Space Telescope science operations will be suspended at midnight tonight EST (06h00 a.m. CET tomorrow) and the HST aperture door closed at 07h30 a.m. EST (01h30 p.m. CET).

  13. PREFACE: Preface

    NASA Astrophysics Data System (ADS)

    Takahashi, Masahiko; Ueda, Kiyoshi

    2011-03-01

    the conference. Finally, the chairs would like to express their thanks to all the participants for contributing to lively and fruitful discussions throughout the conference. Masahiko Takahashi and Kiyoshi Ueda International Advisory Board Lorenzo Avaldi (Italy)Klaus Bartschat (USA) Azzedine Lahmam-Bennani (France)Jamal Berakdar (Germany) Nora Berrah (USA)Igor Bray (Australia) XiangJun Chen (China)Claude Dal Cappello (France) Reinhard Dörner (Germany)Alexander Dorn (Germany) Danielle Dowek (France)Alexey Grum-Grzhimailo (Russia) Noriyuki Kouchi (Japan)Birgit Lohmann (Australia) Don Madison (USA)Fernando Martin (Spain) Andrew Murray (England)Bernard Piraux (Belgium) Roberto Rivarola (Argentina)Emma Sokell (Ireland) Giovanni Stefani (Italy) Conference photograph

  14. From tangles to tau protein.

    PubMed

    Iqbal, K; Novak, M

    2006-01-01

    Alois Alzheimer couldn't have chosen a name more appropriate than neurofibrillary tangles when one hundred years ago (Alzheimer, 1906) he presented this histopathological hallmark of the progressive dementing disorder, which got named after him as Alzheimer disease. Both, the structure and as well as the molecular composition of neurofibrillary tangles have baffled neuroscientists for many years. It was not till 1963 when with the help of the electron microscope the tangles were found to be made up of paired helical filaments (PHF). It took another 23 years before microtubule associated protein tau was immunohistochemically identified as the part of neurofibrillary tangles (Grundke-lqbal, 1986 a). The same year it was shown that tau protein in Alzheimer disease brain was abnormally hyperphosphorylated (Grundke-Iqbal, 1986 b). In 1988 Michal Novak, Cesar Milstein and Claude Wischik produced monoclonal antibody that was able to recognize then unknown protein in PHF. The antibody (MN423) allowed its isolation and let to full molecular characterization as protein tau. These studies provided molecular proof that tau protein was the major and an integral component of the PHF (Wischik et al, 1988 a, b, Goedert et al, 1988, Novak et al, 1989, 1991). Over the years the significance of tau pathology for the neurodegenerative diseases was discussed and often questioned. However, detailed studies of the maturation and distribution of NFTs, showing correlation with degree of cognitive decline and memory impairment in Alzheimer's disease (Braak and Braak, 1991), together with discovery of tau gene mutations causing fronto-temporal dementia in many families (Hutton et al, 1998) promoted tau as the major pathogenic force in neurodegenerative cascade. Further studies focused on tau dysfunctions revealed truncation and phosphorylation as two major posttranslational modifications responsible for toxic gain of function as an underlying cause of tauopathies including Alzheimer

  15. The Protein 4.1 family: hub proteins in animals for organizing membrane proteins.

    PubMed

    Baines, Anthony J; Lu, Hui-Chun; Bennett, Pauline M

    2014-02-01

    differential mRNA splicing. Finally, the spectrum of interactions of the 4.1 proteins overlaps with that of another membrane-cytoskeleton linker, ankyrin. Both ankyrin and 4.1 link to the actin cytoskeleton via spectrin, and we hypothesize that differential regulation of 4.1 proteins and ankyrins allows highly selective control of cell surface protein accumulation and, hence, function. This article is part of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. Guest Editor: Jean Claude Hervé PMID:23747363

  16. Memories of Maurice Jacob (1933-2007) Proceedings of the Maurice Jacob Memorial Meeting (CERN, 11 September 2007) Memories of Maurice Jacob (1933-2007) Proceedings of the Maurice Jacob Memorial Meeting (CERN, 11 September 2007)

    NASA Astrophysics Data System (ADS)

    Alvarez-Gaume, Luis; Heinz, Ulrich

    2008-07-01

    Maurice Jacob passed away unexpectedly on 2 May 2007. Soon after the terrible news arrived, it was thought appropriate to organize a memorial meeting at CERN. The meeting took place on 11 September 2007, and a large number of friends and colleagues participated in the event. The idea was to have brief presentations on the many scientific activities in which Maurice had been engaged, to provide a sketch of his personal trajectory. We also had spontaneous anecdotes and recollections from the audience which, unfortunately, did not make it into this special issue but enriched all of us present. The meeting took place in an afternoon, hence we were faced with the difficult task of selecting from the many presentations that could have been made by his colleagues and collaborators. The end results are the papers contained in this special issue. They provide a short overview of the breadth and depth of Maurice's physics, on the one hand, and of his deep commitment to European and world physics and to the interface between science and society, on the other hand. The first two talks were given by his fellow students and life-long friends Claude Cohen-Tannoudji and Robert Pick. These were mostly personal recollections, less focussed on scientific issues per se but reminding us how Maurice grew into the renowned scientist he later became. Cecilia Jarlskog, a longtime collaborator and friend, provided us with a beautiful view of the wonderfully multifaceted activities Maurice was able to accomplish. Peter Landshoff also spoke about his more than 35 years of personal and scientific interaction with Maurice. The talks presented during the second part of the meeting went a bit more into the technical details of the wide spectrum of scientific activities pursued by Maurice. We had contributions by Helmut Satz (whose transparencies were kindly presented by Urs Wiedemann) and Ulrich Heinz, with the closing talk presented by John Ellis. We have lost a great friend and an excellent

  17. The magnetic field of the planet-hosting star τ Bootis

    NASA Astrophysics Data System (ADS)

    Catala, C.; Donati, J.-F.; Shkolnik, E.; Bohlender, D.; Alecian, E.

    2007-01-01

    We have obtained high-resolution spectropolarimetric data for the planet-hosting star τ Bootis, using the ESPaDOnS spectropolarimeter at the Canada-France-Hawaii Telescope (CFHT). A weak but clear Stokes V signature is detected on three of the four nights of 2006 June during which we have recorded data. This polarimetric signature indicates with no ambiguity the presence of a magnetic field at the star's surface, with intensity of just a few gauss. The analysis of the photospheric lines of τ Boo at ultra-high signal-to-noise ratio reveals the presence of an 18 per cent relative differential rotation. Tentative Zeeman-Doppler imaging, using our spectropolarimetric observations covering only a fraction of the star's rotational phase, indicates a magnetic field with a dominant potential field component. The data are best fitted when a 3.1-d period of modulation and an intermediate inclination are assumed. Considering the level of differential rotation of τ Boo, this implies a rotation period of 3.0 d at the equator and of 3.7 d at the pole, and a topology of the magnetic field where its main non-axisymmetric part is located at low latitudes. The planet is probably synchronized with the star's rotation at intermediate latitudes, while the non-axisymmetric part of the magnetic field seems located at lower latitudes. Our limited data do not provide sufficient constraints on the magnetic field to study a possible interaction of the planet with the star's magnetosphere. Investigating this issue will require data with much better phase coverage. Similar studies should also be performed for other stars hosting close-in giant planets. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii. E-mail: Claude.Catala@obspm.fr (CC); Jean

  18. PREFACE: Nanosafe 2012: International Conferences on Safe Production and Use of Nanomaterials

    NASA Astrophysics Data System (ADS)

    Tardif, François

    2013-04-01

    , FR) Co-chair: Georgios KATALAGARIANAKIS (EC, BE) Mélanie AUFFAN (CEREGE, FR) Jorge BOCZKOWSKI (INSERM, FR) Jean-Yves BOTTERO (CEREGE, FR) Jacques BOUILLARD (INERIS, FR) Derk BROUWER (TNO, NL) Marie CARRIERE (CEA, FR) Claude EMOND (U. MONTREAL, CA) Cassandra ENGEMAN (UCSB, USA) Eric GAFFET (CNRS, FR) François GENSDARMES (IRSN, FR) Alexei GRINBAUM (CEA, FR) Antje GROBE (U.STUTTGART, DE) Peter HOET (KUL, BE) Eric QUEMENEUR (CEA, FR) Olivier LE BIHAN (INERIS, FR) Robert MUIR (NANEUM, UK) Tinh NGUYEN (NIST, USA) Bernd NOWACK (EMPA, CH) Günter OBERDÖRSTER (U. ROCHESTER, USA) David PUI (U. MINNESOTA, USA) Michael RIEDIKER (IST, CH) Yves SAMSON (CEA, FR) Ken TAKEDA (U. TOKYO, JP) Olivier WITSCHGER (INRS, FR) The PDF contains a list of sponsor logos, the conference programme and planning documents.

  19. ARC+(Registered Trademark) and ARC PC Welding Simulators: Teach Welders with Virtual Interactive 3D Technologies

    NASA Technical Reports Server (NTRS)

    Choquet, Claude

    2011-01-01

    123 Certification Inc., a Montreal based company, has developed an innovative hands-on welding simulator solution to help build the welding workforce in the most simple way. The solution lies in virtual reality technology, which has been fully tested since the early 90's. President and founder of 123 Certification Inc., Mr. Claude Choquet Ing. Msc. IWE. acts as a bridge between the welding and the programming world. Working in these fields for more than 20 years. he has filed 12 patents world-wide for a gesture control platform with leading edge hardware related to simulation. In the summer of 2006. Mr Choquet was proud to be invited to the annual IIW International Weld ing Congress in Quebec City to launch the ARC+ welding simulator. A 100% virtual reality system and web based training center was developed to simulate multi process. multi-materiaL multi-position and multi pass welding. The simulator is intended to train welding students and apprentices in schools or industries. The welding simulator is composed of a real welding e[eetrode holder (SMAW-GTAW) and gun (GMAW-FCAW). a head mounted display (HMD), a 6 degrees of freedom tracking system for interaction between the user's hands and head. as well as external audio speakers. Both guns and HMD are interacting online and simultaneously. The welding simulation is based on the law of physics and empirical results from detailed analysis of a series of welding tests based on industrial applications tested over the last 20 years. The simulation runs in real-time, using a local logic network to determine the quality and shape of the created weld. These results are based on the orientation distance. and speed of the welding torch and depth of penetration. The welding process and resulting weld bc.1d are displayed in a virtual environment with screenplay interactive training modules. For review. weld quality and recorded process values can be displayed and diagnosed after welding. To help in the le.tming process, a

  20. [Marcus Aurelius Antonius (121-180AD), philosopher and Roman emperor, and Galen's plague].

    PubMed

    Muñoz-Sanz, Agustín

    2012-11-01

    The study of the aetiologies of diseases in Ancient Times is usually a speculative intellectual exercise. When some authors attribute a specific aetiology to an old disease, there is a great risk of committing a methodological error, known as presentism by the modern historiography. The authority of the investigator, more than the weight of the scientific truth, is usually the reason why the diagnosis has remained over the years. The great epidemic of the years 164-165AD and afterwards, could have been smallpox (haemorrhagic form). Claude Galen, the famous doctor, described the symptoms in several books of his great Opera Omnia. For this reason, it is currently known among the scholars as Galen's plague. The epidemic was described for the first time in Seleucia (Mesopotamia). Until now, the actual geographic origin is unknown. We propose here that the beginning might be the kingdom of the old Han dynasty (now the Chinese Popular Republic). The epidemic swept the Roman Empire, from the east to the west, and from the southern to the northern borders. An immediate consequence of the infection was a high morbidity and mortality. In this sense, Galen's epidemic was one of the many factors that caused the fall and destruction of the Roman Empire. On the other hand, there is a general agreement among historians, biographers and researchers that the philosopher emperor Marcus Aurelius Antoninus (121-180AD was affected by the infection in the epidemic wave of 164-165AD. The death of Marcus Aurelius occurred on March 17 in the year 180AD, in Vindobonne, or perhaps Sirminium (near to Vienna). Many authors propose that the cause of the emperor's death was the same epidemic. We consider that it is not possible to demonstrate any of those speculative diagnoses. Finally, the epidemic of 189-190AD, that we have named of Commodus, was probably a different disease to the Galen's plague. There were several kinds of animals affected (anthropozoonoses). In this sense, this infection

  1. Foreword

    NASA Astrophysics Data System (ADS)

    Boutron, Claude

    2002-11-01

    Earlier this year, with the opening of the 2002 session of the European Research Course on Atmospheres (“ERCA") we celebrated the occasion of the tenth anniversary of ERCA, in the presence of Hubert Curien, President of the French Academy of Sciences and former Minister of Research, Paul Crutzen (1995 Nobel Laureate for Chemistry), Claude Feuerstein (President of University Joseph Fourier of Grenoble) and Philippe Gillet (Director of the National Institute for Universe Sciences). More than 450 participants from 40 different countries in Europe, Asia, America and Africa attended the ten organized sessions, confirming the success of this interdisciplinary course whose characteristics still remain rather unique. Of particular importance for this success, was the publication of a series of books which are the tangible products of the course material. Four books were published in 1994, 1996, 1998 and 2000. They are made up of chapters which present up to date overviews of our present knowledge in a wide range of topics, written by ERCA lecturers who are recognized specialists in these different fields. This volume is the fifth in the series. After an introductory chapter in which Paul Crutzen propounds to name “anthropocene" the present period characterized by the ever increasing impacts of human activities on our environment, it contains nineteen chapters surveying various topics “From the impacts of human activities on our climate and environment to the mysteries of Titan". Particular emphasis is given to the origin of life on Earth, climate change, atmosphere modelling, climate-vegetation interaction, deep sea records of past climate variability, the last glacial maximum, halogen chemistry in the marine boundary layer, the role and fate of trace elements in the environment, mercury as a global pollutant, atmospheric aerosols, emissions of pollutants in Europe, the effect of atmospheric pollution on building materials, air quality assessment, transport phenomena

  2. CONCEPTUAL DESIGN REPORT FOR A FAST MUON TRIGGER

    SciTech Connect

    OBRIEN,E.; BASYE, A.; ISENHOWER, D.; JUMPER, D.; SPARKS, N.; TOWELL, R.; WATTS, C.; WOOD, J.; WRIGHT, R.; HAGGERTY, J.; LYNCH, D.; BARISH, K.; EYSER, K.O.; SETO, R.; HU, S.; LI, X.; ZHOU, S.; GLENN, A.; KINNEY, E.; KIRILUK, K.; NAGLE, J.; CHI, C.Y.; SIPPACH, W.; ZAJC. W.; BUTLER, C.; HE, X.; OAKLEY, C.; YING, J.; BLACKBURN, J.; CHIU, M.; PERDEKAMP, M.G.; KIM, Y.J.; KOSTER, J.; LAYTON, D.; MAKINS, N.; MEREDITH, B.; NORTHACKER, D.; PENG, J.-C.; SEIDL, R.; THORSLAND, E.; WADHAMS, S.; WILLIAMSON, S.; YANG, R.; HILL, J.; KEMPEL, T.; LAJOIE, J.; SLEEGE, G.; VALE, C.; WEI, F.; SAITO, N.; HONG, B.; KIM, B.; LEE, K.; LEE, K.S.; PARK, S.; SIM, K.-S.; AOKI, K.; DAIRAKU, S.; IMAI, K.; KARATSU, K.; MURAKAMI, T.; SATO, A.; SENZAKA, K.; SHOJI, K.; TANIDA, K.; BROOKS, M.; LEITCH, M.; ADAMS, J.; CARINGI, A.; FADEM, B.; IDE, J.; LICHTENWALNER, P.; FIELDS, D.; MAO, Y.; HAN, R.; BUNCE, G.; XIE, W.; FUKAO, Y.; TAKETANI, A.; KURITA, K.; MURATA, J.

    2007-08-01

    This document is a Conceptual Design Report for a fast muon trigger for the PHENIX experiment that will enable the study of flavor separated quark and anti-quark spin polarizations in the proton. A powerful way of measuring these polarizations is via single spin asymmetries for W boson production in polarized proton-proton reactions. The measurement is done by tagging W{sup +} and W{sup -} via their decay into high transverse momentum leptons in the forward directions. The PHENIX experiment is capable of measuring high momentum muons at forward rapidity, but the current online trigger does not have sufficient rejection to sample the rare leptons fromW decay at the highest luminosities at the Relativistic Heavy Ion Collider (RHIC). This Report details the goals, design, R&D, and schedule for building new detectors and trigger electronics to use the full RHIC luminosity to make this critical measurement. The idea for W boson measurements in polarized proton-proton collisions at RHIC was first suggested by Jacques Soffer and Claude Bourrely in 1995. This prompted the RIKEN institute in Japan to supply funds to build a second muon arm for PHENIX (south muon arm). The existence of both a north and south muon arm makes it possible to utilize a Z{sup 0} sample to study and control systematic uncertainties which arise in the reconstruction of high momentum muons. This document has its origins in recommendations made by a NSAC Subcommittee that reviewed the U.S. Heavy Ion Physics Program in June 2004. Part of their Recommendation 1 was to 'Invest in near-term detector upgrades of the two large experiments, PHENIX and STAR'. In Recommendation 2 the subcommittee stated '- detector improvements proceed at a rate that allows a timely determination of the flavor dependence of the quark-antiquark sea polarization through W-asymmetry measurements' as we are proposing here. On September 13, 2004 DOE requested from BNL a report articulating a research plan for the RHIC spin physics

  3. FILAMENT FORMATION BY ESCHERICHIA COLI AT INCREASED HYDROSTATIC PRESSURES1

    PubMed Central

    Zobell, Claude E.; Cobet, Andre B.

    1964-01-01

    ZoBell, Claude E. (University of California, La Jolla), and Andre B. Cobet. Filament formation by Escherichia coli at increased hydrostatic pressures. J. Bacteriol. 87:710–719. 1964.—The reproduction as well as the growth of Escherichia coli is retarded by hydrostatic pressures ranging from 200 to 500 atm. Reproduction was indicated by an increase in the number of cells determined by plating on EMB Agar as well as by direct microscopic counts. Growth, which is not necessarily synonymous with reproduction, was indicated by increase in dry weight and protein content of the bacterial biomass. At increased pressures, cells of three different strains of E. coli tended to form long filaments. Whereas most normal cells of E. coli that developed at 1 atm were only about 2 μ long, the mean length of those that developed at 475 atm was 2.93 μ for strain R4, 3.99 μ for strain S, and 5.82 μ for strain B cells. Nearly 90% of the bacterial biomass produced at 475 atm by strain B was found in filaments exceeding 5 μ in length; 74.7 and 16.4% of the biomass produced at 475 atm by strains S and R4, respectively, occurred in such filaments. Strain R4 formed fewer and shorter (5 to 35 μ) filaments than did the other two strains, whose filaments ranged in length from 5 to >100 μ. The bacterial biomass produced at all pressures had approximately the same content of protein and nucleic acids. But at increased pressures appreciably more ribonucleic acid (RNA) and proportionately less deoxyribonucleic acid (DNA) was found per unit of biomass. Whereas the RNA content per cell increased with cell length, the amount of DNA was nearly the same in long filaments formed at increased pressure as in cells of normal length formed at 1 atm. The inverse relationship between the concentration of DNA and cell length in all three strains of E. coli suggests that the failure of DNA to replicate at increased pressure may be responsible for a repression of cell division and consequent filament

  4. Growth, ion homeostasis, photosynthesis and photosystem II efficiency of an obligate halophyte, Salicornia brachiata, under increasing salinity.

    PubMed

    Parida, A K; Hari Kishore, C M; Jha, B

    2010-04-01

    The following article from Plant Biology, "Growth, ion homeostasis, photosynthesis and photosystem II efficiency of an obligate halophyte, Salicornia brachiata, under increasing salinity (p)" by A. K. Parida, C. M. Hari Kishore & B. Jha, published online on 1 April 2010 (DOI: 10.1111/j.1438-8677.2010.00336.x) in Wiley InterScience (http://www.interscience.wiley.com), has been retracted by agreement between the authors, the journal Editor-in-Chief, Heinz Rennenberg and Blackwell Publishing Ltd. The retraction has been agreed due to concern about overlap with the article "Relationship between the photosynthetic activity and the performance of Cakile maritima after long-term salt treatment" by Ahmed Debez, Hans-Werner Koyro, Claude Grignon, Chedly Abdelly, Bernhard Huchzermeyer published in Physiologia Plantarum (2008) vol. 133, 373-385. ABSTRACT: We examined the effects of salinity (0-600 mm NaCl) on growth, photosynthesis, photosystem II (PSII) efficiency, ion relations and photosynthetic pigment content in Salicornia brachiata. Relative growth rate (RGR) was optimum at 200 mm NaCl and was inhibited at higher salt concentrations; however, relative water content (RWC) of shoots was unaffected by salinity. Accumulation of Na(+) increased with the increase in salinity of shoots, with a concomitant decrease of K(+) and Ca(2+) . Despite the large amount of Na(+) accumulated in shoots of salt-treated plants, neither leaf dehydration nor symptoms of severe shoot injury were noticed, indicating no osmotic or toxic effects of salt because of effective compartmentation of salt in vacuoles. Chlorophyll and carotenoid concentrations increased at optimal salinity and decreased at extreme salinities. Although reduced in the presence of high salt concentrations, chlorophyll and carotenoid content remained relatively high. Net photosynthesis (A), stomatal conductance (g(s) ), intercellular CO(2) concentration (C(i) ), maximum quantum efficiency of PSII (F(v) /F(m) ) and quantum

  5. Radically Different Kinetics at Low Temperatures

    NASA Astrophysics Data System (ADS)

    Sims, Ian

    2014-06-01

    The use of the CRESU (Cinétique de Réaction en Ecoulement Supersonique Uniforme, or Reaction Kinetics in Uniform Supersonic Flow) technique coupled with pulsed laser photochemical kinetics methods has shown that reactions involving radicals can be very rapid at temperatures down to 10 K or below. The results have had a major impact in astrochemistry and planetology, as well as proving an exacting test for theory. The technique has also been applied to the formation of transient complexes of interest both in atmospheric chemistry and combustion. Until now, all of the chemical reactions studied in this way have taken place on attractive potential energy surfaces with no overall barrier to reaction. The F + H2 {→} HF + H reaction does possess a substantial energetic barrier ({\\cong} 800 K), and might therefore be expected to slow to a negligible rate at very low temperatures. In fact, this H-atom abstraction reaction does take place efficiently at low temperatures due entirely to tunneling. I will report direct experimental measurements of the rate of this reaction down to a temperature of 11 K, in remarkable agreement with state-of-the-art quantum reactive scattering calculations by François Lique (Université du Havre) and Millard Alexander (University of Maryland). It is thought that long chain cyanopolyyne molecules H(C2)nCN may play an important role in the formation of the orange haze layer in Titan's atmosphere. The longest carbon chain molecule observed in interstellar space, HC11N, is also a member of this series. I will present new results, obtained in collaboration with Jean-Claude Guillemin (Ecole de Chimie de Rennes) and Stephen Klippenstein (Argonne National Labs), on reactions of C2H, CN and C3N radicals (using a new LIF scheme by Hoshina and Endo which contribute to the low temperature formation of (cyano)polyynes. H. Sabbah, L. Biennier, I. R. Sims, Y. Georgievskii, S. J. Klippenstein, I. W. M. Smith, Science 317, 102 (2007). S. D. Le Picard, M

  6. Reconstruction of the Abdominal Wall in Anatomical Plans. Pre- and Postoperative Keys in Repairing “Cold” Incisional Hernias

    PubMed Central

    POPA, FLORINA; ROSCA, OANA; GEORGESCU, ALEXANDRU; CANNISTRA, CLAUDIO

    2016-01-01

    Background and aims The clinical results of the vertical “vest-over-pants” Mayo repair were evaluated, and the risk factors for incisional hernia recurrence were studied. The purpose of this study is to point out the importance of reducing pre and post operative risk factors in the incisional hernia repair process in order to achieve a physiologically normal abdominal wall. Methods Twenty patients diagnosed with incisional hernia underwent an abdominal reconstruction procedure using the Mayo (Paletot) technique at Bichat Claude Bernard Hospital between 2005 and 2015. All procedures were performed by a single surgeon and all patients were pre-operatively prepared, identifying all coexisting conditions and treating them accordingly before undergoing surgery. Results All patients underwent at least one surgical operation before the hernia repair procedure and a quarter had experienced at least three, prior to this one. Nine patients had a body mass index of >30 kg/m2. Additional risk factors and comorbidities included obesity in 45%, diabetes mellitus in 10%, smoking in 55%, and high blood pressure in 40%. Hernia defect width was from 3 cm (25% F) to 15 cm (5% M) of which nine patients (45%) had a 10 cm defect. Most of the patients had an average hospitalization of 7 days. The patients were carefully monitored and were called on periodic consultations after 3, 6, and 12 months from the moment of the procedure. Patient feedback regarding hernia recurrence and complaints about the scar were noted. Physical examination is essential in determining the hernia recurrence therefore the scar was examined for any abnormalities that may have occurred, which was defined as any palpable or detected fascial defect located within seven centimeters of the hernia repair. Post-operative complications: seroma formation, wound hematoma, superficial and deep wound infection, recurrences and chronic pain were followed and no complications were registered during the follow-up period

  7. Édouard Manet's Tabes Dorsalis: From Painful Ataxia to Phantom Limb.

    PubMed

    Bogousslavsky, Julien; Tatu, Laurent

    2016-01-01

    . Having become bedridden, he had to be amputated of one leg, which was developing gangrene probably associated with ergot overuse. While he died shortly thereafter, we have some witness anecdotes suggesting that he experienced a phantom limb: when Claude Monet (1840-1926) visited him and sat down on his bed, Manet violently shouted at him that he was just sitting on his (absent) leg, which provoked terrible pains. With its facts and mysteries, the subtle interaction between Manet's illness and his work output remains one of the most intriguing stories in neurology of art. PMID:27434214

  8. The study of tropospheric ozone column enhancements over North America using a regional model and the current versions of the Aura satelite data

    NASA Astrophysics Data System (ADS)

    Yang, Q.; Cunnold, D.; Choi, Y.; Wang, Y.

    2008-05-01

    behavior in this region in spring 2006. References: Yang, Q., D. M. Cunnold, H.-J. Wang, L. Froidevaux, H. Claude, J. Merrill, M. Newchurch, and S. J. Oltmans (2007), Midlatitude tropospheric ozone columns derived from the Aura Ozone Monitoring Instrument and Microwave Limb Sounder measurements, J. Geophys. Res., 112, D20305, doi:10.1029/2007JD008528.

  9. Elaboration d'un composite conducteur a base de polypyrrole et de nanofibres de cellulose

    NASA Astrophysics Data System (ADS)

    Bideau, Benoit

    Le projet de production de nanocellulose à grande échelle par l'équipe de recherche du professeur Claude Daneault, ne pourra se faire sans avoir démontré sa quelconque utilité sur le marché économique. C'est dans cette optique que s'est articulé mon travail afin de mettre en avant une des voix de valorisation de ces nanocelluloses. Nous avons travaillé plus précisément sur le développement d'un nanocomposite conducteur biodégradable. Nous nous sommes proposé dans ce travail de développer une technique simple et écologique permettant la conception d'un matériau composite conducteur. Nous avons étudié l'influence des nanofibres de cellulose, du pyrrole, de la température, de la durée de polymérisation et l'ajout d'additifs dans le matériau composite. L'étude de ces paramètres nous a permis de déterminer les meilleures conditions pour le développement d'un film composite conducteur avec des propriétés mécaniques acceptables. L'ajout de ce renfort (nanofibres), au sein de la matrice de polypyrrole a permis d'obtenir des films intéressants, de part leurs propriétés mécaniques, électriques et de leur caractère biodégradable. Des comparaisons ont été effectuées avec des fibres oxydées, afin d'étudier l'apport des nanofibres de cellulose au composite. Notre étude a ensuite été élargie à l'ajout d'additifs dans les matériaux conducteurs afin d'améliorer certaines propriétés du composite. L'objectif de ce travail visait l'étude de l'incorporation des nanofibres de cellulose dans une matrice de polypyrrole en vue de son utilisation en tant que matériau conducteur biodégradable pour des applications dans le domaine énergétique. Mots Clés: Nanocellulose, polypyrrole, composite, conducteur, biodégradable, propriétés mécaniques, additifs.

  10. European astronaut selected for the third Hubble Space Telescope

    NASA Astrophysics Data System (ADS)

    1998-08-01

    The STS-104 crew will rendezvous with the orbiting Hubble Space Telescope, which is the size of a city bus, capture it using the Shuttle's Canadian robot arm and secure it in Columbia's payload bay. Then, working in teams of two, the four astronauts will leave the Shuttle's pressurised cabin and venture into the payload bay, performing a variety of tasks that will improve the productivity and reliability of the telescope. The four astronauts will perform a series of six "extravehicular" activities in the open space environment. Such activities are commonly called spacewalks, but this term does little justice to the considerable physical and mental efforts that astronauts need to make in doing the very demanding work involved. The Shuttle commander and pilot for this flight have not yet been appointed, but the four designated mission specialists begin training for the STS-104 mission immediately. "The ambitious nature of this mission, with its six spacewalks, made it important for the payload crew to begin training as early as possible," said David C. Leestma, NASA Director of Flight Crew Operations at the Johnson Space Center in Houston, to which Claude Nicollier is on resident assignment from ESA's European Astronaut Centre in Cologne, Germany, the home base of the European astronaut corps. The Hubble Space Telescope was launched into orbit in April 1990. It is one of the most capable optical telescopes available to astronomers today, producing images and spectral observations at the forefront of astronomy. The European Space Agency contributed a 15 share to the development of Hubble. One of the five scientific instruments on board, the Faint Object Camera, was built by a European industrial consortium made up of British Aerospace, Dornier and Matra under a contract with the European Space Agency. The solar arrays which provide Hubble with electrical power were manufactured by British Aerospace and Dornier. In its eight years of operation, the telescope has not

  11. The weak magnetic field of the O9.7 supergiant ζOrionisA

    NASA Astrophysics Data System (ADS)

    Bouret, J.-C.; Donati, J.-F.; Martins, F.; Escolano, C.; Marcolino, W.; Lanz, T.; Howarth, I. D.

    2008-09-01

    . E-mail: jean-claude.bouret@oamp.fr

  12. PREFACE: 17th International Conference on Textures of Materials (ICOTOM 17)

    NASA Astrophysics Data System (ADS)

    Skrotzki, Werner; Oertel, Carl-Georg

    2015-04-01

    ceremony honoring Prof. Dr. Claude Esling with the Bunge Award for his distinguished contributions to the field of Textures of Materials and his continuous effort to pass on his knowledge to future generations of texture experts. The Bunge Award is named after Professor Hans Bunge († 2004), to whom the world's texture community is very much indebted not only for his magisterial work on the Mathematical Theory of Texture, but also for his lifelong promotion of the field of Textures of Materials. To the great delight of all participants, Helga Bunge and her son Prof. Hans-Peter Bunge, to whom many of the older generation have a personal relationship, attended the ceremony (see Fig. 1 in the PDF). Following the award ceremony Prof. Dr. Claude Esling gave an in memoriam tribute to Prof. Dr. Richard Penelle, who was an internationally recognized texture specialist. Details can be found in the proceedings paper by Esling et al. [this issue]. During the conference the International ICSMA Committee decided to convene the next conference in St. George, USA, in 2017. We wish the organizers of ICOTOM 18 great success and look forward to meeting you in St. George. Werner Skrotzki* (Chairman of ICOTOM 17, Dresden University of Technology) Carl-Georg Oertel (Dresden University of Technology) Guest Editors Dresden, March, 2015 (* Corresponding author; e-mail address: werner.skrotzki@tu-dresden.de)

  13. Foreword

    NASA Astrophysics Data System (ADS)

    Aime, C.; Soummer, R.

    very short explanation of how the reports are ordered is given here. The Journées of 2003 started with the delocalized lectures (delocalized means here “not in Paris”!) of the Collège de France, of Antoine Labeyrie who wrote a report on Removal of coronagraphy residues with an adaptive hologram. Three invited seminars follow: Olivier Guyon (Pupil remapping techniques), Daniel Rouan (Ultra-nulling interferometers), and Kjetil Dohlen (Phase masks in astronomy). An illustration from Daniel Rouan's talk on the properties of Prouhet-Thué-Morse series was also selected for the cover figure of this edition. These papers are followed by the courses and communications given during the 4 days of the school, in a slightly different order of their presentation. The first two days were on atmospheric turbulence and adaptive optics for coronagraphy, and also coronagraphic space projects. Steve Ridgway gives a general introduction to the problem (Astronomy with high contrast imaging). This is followed by a presentation on Fourier and Statistical Optics: Shaped and Apodized apertures (Claude Aime), The effect of a coronagraph on the statistics of adaptive optics pinned speckles (Claude Aime and Rémi Soummer). A general introduction to the problem of atmospheric turbulence is made by Julien Borgnino. A presentation of the Concordia site with emphasis on its advantages for high contrast imaging is given by Eric Fossat. Several presentations relative to numerical simulations of Adaptive Optics and coronagraphy follow: Marcel Carbillet (AO for very high contrast imaging), Lyu Abe and Anthony Boccaletti share two presentations on Numerical simulations for coronagraphy. These presentations are followed by reports on experiments: Sandrine Thomas (SAM-the SOAR adaptive module), Pierre Baudoz (Cryogenic IR test of the 4QPM coronagraph), Anthony Boccaletti (Coronagraphy with JWST in the thermal IR). Pierre Bourget (Hg-Mask Coronagraph) ends this part with a coronagraph using a mercury

  14. PREFACE: XII Latin American workshop on plasma physics (17-21 September 2007, Caracas, Venezuela)

    NASA Astrophysics Data System (ADS)

    Puerta, Julio

    2008-10-01

    Some years ago a group of Latin American physicists took the initiative to consult about the viability of organizing a meeting on plasma physics for researchers and students of the region. The result was that it was not only a good idea, but a necessity in order to show and share everyone's work, and to keep updated on latest advances and technologies on plasma physics. It was decided that for new researchers as well as students of Physics, it would prove to be the best way to keep them posted on such matters. This was the birth of a series of meetings known as Latin American workshops on plasma physics that take place every two years in a different Latin American country. In Venezuela we have had the opportunity to organize two editions of this interesting and important reunion of physicists. The first of these Latin American workshops on plasma physics was held in Cambuquira (Brazil) in 1982. After organizing the first six editions of the workshop, the VII LAWPP meeting was realized in Caracas in January 1997. It was designed with a structure similar to the first edition. It developed in two stages, a first week devoted to short courses with lecturers in different fields of plasma physics and a second week for contributed and invited presentations. Participants from sixteen different countries were present, half of them from this continent and the other half from overseas, demonstrating the international character of this meeting. There have been four more editions of the workshop and once again, we have had the opportunity to organize this latest edition of the series: the XII Latin American workshop on plasma physics, which took place in Caracas, Venezuela from the 17th to the 21st of September 2007. The structure was modified, because contributed and review papers were together during the first stage, with short courses realized during the second one, called mini-courses, and given by several high level contributors such as José Boedo, Leopoldo Soto, Claude

  15. Galactic Super-volcano in Action

    NASA Astrophysics Data System (ADS)

    2010-08-01

    A galactic "super-volcano" in the massive galaxy M87 is erupting and blasting gas outwards, as witnessed by NASA's Chandra X-ray Observatory and NSF's Very Large Array. The cosmic volcano is being driven by a giant black hole in the galaxy's center and preventing hundreds of millions of new stars from forming. Astronomers studying this black hole and its effects have been struck by the remarkable similarities between it and a volcano in Iceland that made headlines earlier this year. At a distance of about 50 million light years, M87 is relatively close to Earth and lies at the center of the Virgo cluster, which contains thousands of galaxies. M87's location, coupled with long observations over Chandra's lifetime, has made it an excellent subject for investigations of how a massive black hole impacts its environment. "Our results show in great detail that supermassive black holes have a surprisingly good control over the evolution of the galaxies in which they live," said Norbert Werner of the Kavli Institute for Particle Astrophysics and Cosmology at Stanford University and the SLAC National Accelerator Laboratory, who led one of two papers describing the study. "And it doesn't stop there. The black hole's reach extends ever farther into the entire cluster, similar to how one small volcano can affect practically an entire hemisphere on Earth." The cluster surrounding M87 is filled with hot gas glowing in X-ray light, which is detected by Chandra. As this gas cools, it can fall toward the galaxy's center where it should continue to cool even faster and form new stars. However, radio observations with the Very Large Array suggest that in M87 jets of very energetic particles produced by the black hole interrupt this process. These jets lift up the relatively cool gas near the center of the galaxy and produce shock waves in the galaxy's atmosphere because of their supersonic speed. The scientists involved in this research have found the interaction of this cosmic

  16. EDITORIAL Proceedings of the XIV International Conference on Small-Angle Scattering, SAS-2009

    NASA Astrophysics Data System (ADS)

    Ungar, Goran; Heenan, Richard

    2010-10-01

    papers by Felisa Berenguer and the Diamond/UCL team (012004) and by Birgit Fischer and the DESY/Rostock team (012026). The former describe their effort to reconstruct the image of wet collagen tissue from the speckled pattern of a narrow transmitted beam and complement the results of imaging by scanning SAXS. Fischer et al. utilize the coherence of the X-ray beam in the photon correlation spectroscopy mode to determine the dynamic structure factor, from which the q-dependence of the relaxation times was determined for solutions of charged colloidal particles. The nature of particle motion was thus determined, i.e. ballistic at lower concentrations vs. restricted by 'caging' at higher concentrations. The use of scanning microbeam diffraction was also described in the paper by the group of Peter Fratzl (012031), who combined it with tilting the sample in order to obtain what is referred to as 3D SAXS. In this way the orientation distribution of crystallites in callus tissue during bone fracture healing can be explored. Naoto Yagi et al. (012024) used microbeam SAXS and WAXS to study dental enamel crystals in a caries lesion. Anomalous, or resonant, X-ray scattering at low angles (ASAXS) was employed by Guenter Goerigk and Norbert Mattern (Jülich/Dresden) (012022) to study phase separation in the ternary alloy Ni-Nb-Y. Experiments were performed near the K-absorption edges of the three elements and the authors describe how they determined quantitatively the chemical composition of the different separate phases as well as short-range concentration fluctuations during spinodal decomposition. For organic materials, where heavy atoms are not present, typically sulphur would be replaced by Se, so ASAXS could be performed near the Se K-edge. However, Masashi Handa et al. from the University of Tokyo report in paper 012006 a feasibility study of using sulphur itself as the label. They deal with the challenging task of using low-energy X-rays at the sulphur K-edge. Alexandra

  17. Powerful Nearby Supernova Caught By Web

    NASA Astrophysics Data System (ADS)

    2008-09-01

    previously thought, but it also teaches us more about the tremendous upheavals that massive stars can undergo during their lifetime," said co-author Vikram Dwarkadas of the University of Chicago. SN 1996cr, at a distance of about 12 million light years, will be a compelling target for future work because it is nearby and so much brighter than a typical supernova. These results will appear in an upcoming issue of The Astrophysical Journal. Other co-authors on this paper include Niel Brandt (Penn State), Stefan Immler (NASA Goddard Space Flight Center), Norbert Bartel (York University, Canada), and Michael Bietenholz (York University and Hartebeesthoek Radio Observatory, South Africa). NASA's Marshall Space Flight Center, Huntsville, Ala., manages the Chandra program for the agency's Science Mission Directorate. The Smithsonian Astrophysical Observatory controls science and flight operations from the Chandra X-ray Center in Cambridge, Mass.

  18. Chandra Discovers the X-ray Signature of a Powerful Wind from a Galactic Microquasar

    NASA Astrophysics Data System (ADS)

    2000-11-01

    NASA's Chandra X-ray Observatory has detected, for the first time in X rays, a stellar fingerprint known as a P Cygni profile--the distinctive spectral signature of a powerful wind produced by an object in space. The discovery reveals a 4.5-million-mile-per-hour wind coming from a highly compact pair of stars in our galaxy, report researchers from Penn State and the Massachusetts Institute of Technology in a paper they will present on 8 November 2000 during a meeting of the High-Energy Astrophysics Division of the American Astronomical Society in Honolulu, Hawaii. The paper also has been accepted for publication in The Astrophysical Journal Letters. "To our knowledge, these are the first P Cygni profiles reported in X rays," say researchers Niel Brandt, assistant professor of astronomy and astrophysics at Penn State, and Norbert S. Schulz, research scientist at the Massachusetts Institute of Technology. The team made the discovery during their first observation of a binary-star system with the Chandra X-ray Observatory, which was launched into space in July 1999. The system, known as Circinus X-1, is located about 20,000 light years from Earth in the constellation Circinus near the Southern Cross. It contains a super-dense neutron star in orbit around a normal fusion-burning star like our Sun. Although Circinus X-1 was discovered in 1971, many properties of this system remain mysterious because Circinus X-1 lies in the galactic plane where obscuring dust and gas have blocked its effective study in many wavelengths. The P Cygni spectral profile, previously detected primarily at ultraviolet and optical wavelengths but never before in X rays, is the textbook tool astronomers rely on for probing stellar winds. The profile looks like the outline of a roller coaster, with one really big hill and valley in the middle, on a data plot with velocity on one axis and the flow rate of photons per second on the other. It is named after the famous star P Cygni, in which such

  19. World's fastest and most sensitive astronomical camera

    NASA Astrophysics Data System (ADS)

    2009-06-01

    The next generation of instruments for ground-based telescopes took a leap forward with the development of a new ultra-fast camera that can take 1500 finely exposed images per second even when observing extremely faint objects. The first 240x240 pixel images with the world's fastest high precision faint light camera were obtained through a collaborative effort between ESO and three French laboratories from the French Centre National de la Recherche Scientifique/Institut National des Sciences de l'Univers (CNRS/INSU). Cameras such as this are key components of the next generation of adaptive optics instruments of Europe's ground-based astronomy flagship facility, the ESO Very Large Telescope (VLT). ESO PR Photo 22a/09 The CCD220 detector ESO PR Photo 22b/09 The OCam camera ESO PR Video 22a/09 OCam images "The performance of this breakthrough camera is without an equivalent anywhere in the world. The camera will enable great leaps forward in many areas of the study of the Universe," says Norbert Hubin, head of the Adaptive Optics department at ESO. OCam will be part of the second-generation VLT instrument SPHERE. To be installed in 2011, SPHERE will take images of giant exoplanets orbiting nearby stars. A fast camera such as this is needed as an essential component for the modern adaptive optics instruments used on the largest ground-based telescopes. Telescopes on the ground suffer from the blurring effect induced by atmospheric turbulence. This turbulence causes the stars to twinkle in a way that delights poets, but frustrates astronomers, since it blurs the finest details of the images. Adaptive optics techniques overcome this major drawback, so that ground-based telescopes can produce images that are as sharp as if taken from space. Adaptive optics is based on real-time corrections computed from images obtained by a special camera working at very high speeds. Nowadays, this means many hundreds of times each second. The new generation instruments require these

  20. Galactic Super-volcano in Action

    NASA Astrophysics Data System (ADS)

    2010-08-01

    A galactic "super-volcano" in the massive galaxy M87 is erupting and blasting gas outwards, as witnessed by NASA's Chandra X-ray Observatory and NSF's Very Large Array. The cosmic volcano is being driven by a giant black hole in the galaxy's center and preventing hundreds of millions of new stars from forming. Astronomers studying this black hole and its effects have been struck by the remarkable similarities between it and a volcano in Iceland that made headlines earlier this year. At a distance of about 50 million light years, M87 is relatively close to Earth and lies at the center of the Virgo cluster, which contains thousands of galaxies. M87's location, coupled with long observations over Chandra's lifetime, has made it an excellent subject for investigations of how a massive black hole impacts its environment. "Our results show in great detail that supermassive black holes have a surprisingly good control over the evolution of the galaxies in which they live," said Norbert Werner of the Kavli Institute for Particle Astrophysics and Cosmology at Stanford University and the SLAC National Accelerator Laboratory, who led one of two papers describing the study. "And it doesn't stop there. The black hole's reach extends ever farther into the entire cluster, similar to how one small volcano can affect practically an entire hemisphere on Earth." The cluster surrounding M87 is filled with hot gas glowing in X-ray light, which is detected by Chandra. As this gas cools, it can fall toward the galaxy's center where it should continue to cool even faster and form new stars. However, radio observations with the Very Large Array suggest that in M87 jets of very energetic particles produced by the black hole interrupt this process. These jets lift up the relatively cool gas near the center of the galaxy and produce shock waves in the galaxy's atmosphere because of their supersonic speed. The scientists involved in this research have found the interaction of this cosmic

  1. PREFACE: Loops 11: Non-Perturbative / Background Independent Quantum Gravity

    NASA Astrophysics Data System (ADS)

    Mena Marugán, Guillermo A.; Barbero G, J. Fernando; Garay, Luis J.; Villaseñor, Eduardo J. S.; Olmedo, Javier

    2012-05-01

    only was it a showroom for the research currently being carried out by many groups throughout the world, but there was also a permanent look towards the future. During these days, the CSIC Campus witnessed many scientific conversations triggered by the interaction amongst the people and groups that participated in LOOPS'11 Madrid and which, in many cases, will crystallise into new results and advances in the field. The conference would not have been possible without the generous help of a number of national and international institutions. The organizers would like to acknowledge the financial support provided by the Spanish Ministry of Science and Innovation (Ministerio de Ciencia e Innovación), the Spanish Research Council, CSIC (Consejo Superior de Investigaciones Cientĺficas), The BBVA Foundation (Fundación BBVA), The CONSOLIDER-CPAN project, the Spanish Society for Gravitation and Relativity (SEGRE), The Universidad Carlos III of Madrid (UC3M), and the European Science Foundation (ESF). The ESF, through the Quantum Gravity and Quantum Geometry network, provided full support for a number of young participants that have contributed to these proceedings: Dario Benedetti (Albert Einstein Institute, Potsdam, Germany), Norbert Bodendorfer (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Mariam Bouhmadi López (CENTRA, Centro Multidisciplinar de Astrofĺsica, Lisbon), Timothy Budd (Institute for Theoretical Physics, Utrecht University, The Netherlands), Miguel Campiglia (Institute for Gravitation and the Cosmos, Penn State University, USA), Gianluca Delfino (School of Mathematical Sciences, University of Nottingham, UK), Maite Dupuis (Institute for Theoretical Physics III, FAU Erlangen Nürnberg, Germany), Michał Dziendzikowski (Institute of Theoretical Physics, Warsaw University, Poland), Muxin Han (Centre de Physique Théorique de Luminy, Marseille, France), Philipp Höhn (Institute for Theoretical Physics, Utrecht University, The

  2. Argonne National Laboratory summary site environmental report for calendar year 2007.

    SciTech Connect

    Golchert, N. W.

    2009-05-22

    same standard requires that Illinois students examine the impact of diminishing biodiversity due to human activity. An example of this would be the Argonne Restoration Prairie, which is discussed within the report. Because humans had to destroy part of a natural prairie in order to build, they must also plant an equivalent amount of prairie to make up for what was destroyed. The summary project perfectly meets Illinois State Learning Standard 13B section 5b, which requires students to be able to design and conduct an environmental impact study, analyze findings, and justify recommendations. Students volunteered for the project for two main reasons: We would become published authors, and could include that fact on important documents, like college applications, and we felt we were doing a good deed for the public, considering that without our summary the public may have no real idea how Argonne complies with various environmental protection acts and programs within the state. The summarization process was not easy, considering that we had never seen much of this kind of information before, especially in such detail. The project required a high level of commitment from all involved. This commitment ensured that the summary would be done on time and would be available to the public in the shortest time possible. Argonne representatives Norbert Golchert and Dave Baurac met with students and gave background information on Argonne and explained the importance of the research being done. In addition, they explained in-depth how the public benefits from the summarization. At the end of the presentation, students asked some questions, which were answered in specifics. The Report was divided into 10 sections, with groups of two students covering each section. The groups were eager to begin work on their assigned sections. After reading the complete report each group focused on a particular section. After much careful reading and analysis, we produced an outline. From the outline

  3. Chandra Observatory Uncovers Hot Stars In The Making

    NASA Astrophysics Data System (ADS)

    2000-11-01

    their type," said Norbert S. Schulz, MIT research scientist at the Chandra X-ray Center, who leads the Orion Project. "And by extreme, we mean temperatures which are in some cases well above 60 million degrees." The hottest massive star known so far has been around 25 million degrees. The great Orion Nebula harbors the Orion Nebula Cluster (ONC), a loose association of around 2,000 mostly very young stars of a wide range of mass confined within a radius of less than 10 light years. The Orion Trapezium Cluster is a younger subgroup of stars at the core of the ONC confined within a radius of about 1.5 light years. Its median age is around 300,000 years. The constant bright light of the Trapezium and its surrounding stars at the heart of the Orion nebula (M42) are visible to the naked eye on clear nights. In X-rays, these young stars are constantly active and changing in brightness, sometimes within half a day, sometimes over weeks. "Never before Chandra have we seen images of stellar activity with such brilliance," said Joel Kastner, professor at the Chester F. Carlson Center for Imaging Science at the Rochester Institute of Technology. "Here the combination of very high angular resolution, with high quality spectra that Chandra offers, clearly pays off." The observation was performed using the High Energy Transmission Grating Spectrometer (HETGS) and the X-ray spectra were recorded with the spectroscopic array of the Advanced CCD Imaging Spectrometer (ACIS). The ACIS detector is a sophisticated version of the CCD detectors commonly used in video cameras or digital cameras. The orion stars are so bright in X-rays that they easily saturate the ccds. Here the team used the gratings as a blocking filter. Orion Trapezium - X-ray & Optical JPEG, TIFF, PS X-ray contours of the Chandra observation overlaid onto the optical Hubble image (courtesy of J. Bally, CASA Colorado). The field of view is 30"x30". Besides the bright main Trapezium stars, which were found to be extremely

  4. How Much Mass Makes a Black Hole? - Astronomers Challenge Current Theories

    NASA Astrophysics Data System (ADS)

    2010-08-01

    exploded and left a magnetar remnant must have had a shorter life than the surviving stars in the cluster. "Because the lifespan of a star is directly linked to its mass - the heavier a star, the shorter its life - if we can measure the mass of any one surviving star, we know for sure that the shorter-lived star that became the magnetar must have been even more massive," says co-author and team leader Simon Clark. "This is of great significance since there is no accepted theory for how such extremely magnetic objects are formed." The astronomers therefore studied the stars that belong to the eclipsing double system W13 in Westerlund 1 using the fact that, in such a system, masses can be directly determined from the motions of the stars. By comparison with these stars, they found that the star that became the magnetar must have been at least 40 times the mass of the Sun. This proves for the first time that magnetars can evolve from stars so massive we would normally expect them to form black holes. The previous assumption was that stars with initial masses between about 10 and 25 solar masses would form neutron stars and those above 25 solar masses would produce black holes. "These stars must get rid of more than nine tenths of their mass before exploding as a supernova, or they would otherwise have created a black hole instead," says co-author Ignacio Negueruela. "Such huge mass losses before the explosion present great challenges to current theories of stellar evolution." "This therefore raises the thorny question of just how massive a star has to be to collapse to form a black hole if stars over 40 times as heavy as our Sun cannot manage this feat," concludes co-author Norbert Langer. The formation mechanism preferred by the astronomers postulates that the star that became the magnetar - the progenitor - was born with a stellar companion. As both stars evolved they would begin to interact, with energy derived from their orbital motion expended in ejecting the requisite

  5. PREFACE: A Stellar Journey A Stellar Journey

    NASA Astrophysics Data System (ADS)

    Asplund, M.

    2008-10-01

    appreciated non-astronomical session on Tuesday afternoon; Sigbritt Ernald provided a rich source of suggestions for suitable interesting persons to invite for the stimulating and highly enjoyable oral and musical presentations. While the responsibilities of the SOC are quite pleasant and frankly not particularly demanding, the heavy burden with organizing a conference falls squarely with the Local Organizing Committee, which has to deal with a seemingly never-ending stream of practicalities and more mundane chores. The main reason the Stellar Journey conference was such an astounding success and ran so smoothly is the tireless work by the whole LOC. All of us owe a great deal of gratitude to Paul Barklem, Nils Bergvall, Norbert Christlieb, Bengt Edvardsson (Chair), Kjell Eriksson, Ulrike Heiter, Susanne Höfner, Andreas Korn, Nikolai Piskunov, Bertrand Plez and Astrid Wachter for their extensive efforts. I'd like to also extend a special acknowledgement to all of the Uppsala students who helped out during the reception, registration and various sessions. Last but not the least, I'd like to thank all of the conference participants for giving such excellent talks and for providing stimulating discussions throughout the week. It is telling that essentially everyone invited to participate in the conference almost immediately accepted while the very few who declined did so only reluctantly due to other prior commitments. Bengt is a highly regarded colleague and friend, whom we all wished to celebrate this special occasion with. This conference represented merely one brief stop on a marvellous and truly stellar journey. I dare say that without exception we are all deeply thankful for having been able to join Bengt Gustafsson on at least some of his many cosmic adventures during the past decades. We trust that this exciting odyssey will continue for many years.

  6. The history of British gynaecological pathology.

    PubMed

    Young, Robert H

    2009-01-01

    for the acceptance in Britain of the concepts of trophoblastic disease espoused by the German investigator Felix Marchand. Wallace Park of Dundee also contributed significantly on trophoblastic disease in later years. The years following the death of Dr Teacher were largely dominated by three individuals, Magnus Haines working in London, Claud Taylor in Birmingham, and Frederick Langley in Manchester. The first two individuals wrote an excellent textbook and Langley brought great fame to the Manchester School, ably assisted by Harold Fox, the latter being the doyen of British gynaecologic pathologists throughout the latter decades of the 20th century. With Langley he wrote an important book on ovarian tumours, an equally influential book on the placenta, and with Dr Hilary Buckley he authored a book on endometrial biopsy interpretation. Additionally, his countless entertaining and instructive lectures throughout the world represented a remarkable educational experience. PMID:19207941

  7. PREFACE: 17th International Conference on Textures of Materials (ICOTOM 17)

    NASA Astrophysics Data System (ADS)

    Skrotzki, Werner; Oertel, Carl-Georg

    2015-04-01

    ceremony honoring Prof. Dr. Claude Esling with the Bunge Award for his distinguish

  8. PREFACE: Peyresq Physics Workshops 11 and 12—'Micro and Macro Structure of Spacetime', Peyresq, Alpes de Haute Provence, France (17 23 June 2006 and 16 22 June 2007)

    NASA Astrophysics Data System (ADS)

    Arteaga, D.; Verdaguer, E.

    2008-08-01

    -optical and condensed matter physics. The richness of this theme spans a diverse spectrum of current topics which can be gleaned from the titles of the talks presented in these two meetings. Peyresq is a medieval Provençal village situated 100km from Nice at an altitude of 1528m. The village was founded in the early 13th century. At the beginning of the 17th century there were around 50 houses and by 1851 the village counted 208 inhabitants distributed among 53 families. Like many other villages of Haute Provence, it was almost completely deserted after the Second World War. During the 1950s the village was progressively entirely rebuilt in its original spirit and style by students of Belgian universities, mainly the Université Libre de Bruxelles, under the guidance of Mady and Toine Smets. The aim was to create a 'Foyer d'Humanisme', an international humanistic center for cultural, artistic, and scientific pursuits. The workshops were financed by the Fondation Peyresq, Foyer d'Humanisme, the Fondation Nicolas Claude Fabri de Peyresq, and OLAM (Association pour la Recherche Fondamentale, Brussels). We would like to thank all these institutions for their help and financial support. We extend our warm appreciation to Madame Mady Smets without whom none of this work could have come to light. We would like to thank all the participants for the many lively discussions that we have enjoyed and for their effort in preparing written contributions. We would also like to thank the editorial staff of Classical and Quantum Gravity, especially Tom Spicer, Joseph Tennant and Eirini Messaritaki, for their support and efficiency in preparing this volume. Finally, we thank Edgar Gunzig and Bei-Lok Hu as the main driving forces behind the organization of these workshops.

  9. PREFACE: Strongly Coupled Coulomb Systems

    NASA Astrophysics Data System (ADS)

    Fortov, Vladimir E.; Golden, Kenneth I.; Norman, Genri E.

    2006-04-01

    This special issue contains papers presented at the International Conference on Strongly Coupled Coulomb Systems (SCCS) which was held during the week of 20 24 June 2005 in Moscow, Russia. The Moscow conference was the tenth in a series of conferences. The previous conferences were organized as follows. 1977: Orleans-la-Source, France, as a NATO Advanced Study Institute on Strongly Coupled Plasmas (organized by Marc Feix and Gabor J Kalman) 1982: Les Houches, France (organized by Marc Baus and Jean-Pierre Hansen) 1986: Santa Cruz, California, USA (hosted by Forrest J Rogers and Hugh E DeWitt) 1989: Tokyo, Japan (hosted by Setsuo Ichimaru) 1992: Rochester, NY, USA (hosted by Hugh M Van Horn and Setsuo Ichimaru) 1995: Binz, Germany (hosted by Wolf Dietrich Kraeft and Manfred Schlanges) 1997: Boston, Massachusetts, USA (hosted by Gabor J Kalman) 1999: St Malo, France (hosted by Claude Deutsch and Bernard Jancovici) 2002: Santa Fe, New Mexico, USA (hosted by John F Benage and Michael S Murillo) After 1995 the name of the series was changed from `Strongly Coupled Plasmas' to the present name in order to extend the topics of the conferences. The planned frequency for the future is once every three years. The purpose of these conferences is to provide an international forum for the presentation and discussion of research accomplishments and ideas relating to a variety of plasma liquid and condensed matter systems, dominated by strong Coulomb interactions between their constituents. Strongly coupled Coulomb systems encompass diverse many-body systems and physical conditions. Each meeting has seen an evolution of topics and emphasis as new discoveries and new methods appear. This year, sessions were organized for invited presentations and posters on dense plasmas and warm matter, astrophysics and dense hydrogen, non-neutral and ultracold plasmas, dusty plasmas, condensed matter 2D and layered charged-particle systems, Coulomb liquids, and statistical theory of SCCS. Within

  10. PREFACE: Strongly Coupled Coulomb Systems Strongly Coupled Coulomb Systems

    NASA Astrophysics Data System (ADS)

    Neilson, David; Senatore, Gaetano

    2009-05-01

    This special issue contains papers presented at the International Conference on Strongly Coupled Coulomb Systems (SCCS), held from 29 July-2 August 2008 at the University of Camerino. Camerino is an ancient hill-top town located in the Apennine mountains of Italy, 200 kilometres northeast of Rome, with a university dating back to 1336. The Camerino conference was the 11th in a series which started in 1977: 1977: Orleans-la-Source, France, as a NATO Advanced Study Institute on Strongly Coupled Plasmas (hosted by Marc Feix and Gabor J Kalman) 1982: Les Houches, France (hosted by Marc Baus and Jean-Pierre Hansen) 1986: Santa Cruz, California, USA (hosted by Forrest J Rogers and Hugh E DeWitt) 1989: Tokyo, Japan (hosted by Setsuo Ichimaru) 1992: Rochester, New York, USA (hosted by Hugh M Van Horn and Setsuo Ichimaru) 1995: Binz, Germany (hosted by Wolf Dietrich Kraeft and Manfred Schlanges) 1997: Boston, Massachusetts, USA (hosted by Gabor J Kalman) 1999: St Malo, France (hosted by Claude Deutsch and Bernard Jancovici) 2002: Santa Fe, New Mexico, USA (hosted by John F Benage and Michael S Murillo) 2005: Moscow, Russia (hosted by Vladimir E Fortov and Vladimir Vorob'ev). The name of the series was changed in 1996 from Strongly Coupled Plasmas to Strongly Coupled Coulomb Systems to reflect a wider range of topics. 'Strongly Coupled Coulomb Systems' encompasses diverse many-body systems and physical conditions. The purpose of the conferences is to provide a regular international forum for the presentation and discussion of research achievements and ideas relating to a variety of plasma, liquid and condensed matter systems that are dominated by strong Coulomb interactions between their constituents. Each meeting has seen an evolution of topics and emphases that have followed new discoveries and new techniques. The field has continued to see new experimental tools and access to new strongly coupled conditions, most recently in the areas of warm matter, dusty plasmas

  11. Chandra Observes Cloud Powered by Black Hole in Distant Galaxy

    NASA Astrophysics Data System (ADS)

    2000-06-01

    NASA's Chandra X-ray Observatory has shown that a large gas cloud is being blasted by X rays from the vicinity of a giant black hole which lurks in its center. The observation is of special interest because it shows the disruptive effects that a massive black hole can have over thousands of light years. The results are being presented today by Drs. Patrick M. Ogle, Herman L. Marshall, Julia C. Lee, and Claude Canizares of the Massachusetts Institute of Technology (MIT), Cambridge, at the 196th national meeting of the American Astronomical Society in Rochester, NY. The observation also demonstrates that the searchlight beam of X rays from the black hole can be used to probe the environment around a black hole. The galaxy NGC 4151 is located at a distance of 50 million light years in a direction just south of the Big Dipper. It is a prominent example of a class of galaxies that show unusual energetic activity in their nucleus. This activity is now known to be due to the presence of a giant black hole in the nucleus with an estimated mass 10 million times that of the Sun. As matter swirls toward the black hole, it releases a prodigious amount of energy, much of it in X rays. Previous observations showed that X rays are also coming from an enormous cloud 3000 light years across that surrounds the black hole. The precise mirrors of Chandra allowed astronomers to make an X-ray image showing unprecedented detail of the massive cloud in the center of NGC 4151. The brightest regions in the cloud correspond to wisps that were previously observed in visible light by the Hubble Space Telescope. The shape of the cloud confirms that X rays from the black hole are collimated into a narrow beam, and illuminate only certain quadrants of the galaxy. "The black hole is shining an X-ray searchlight which illuminates the clouds in the night sky of NGC 4151" said Ogle. By using the High Energy Transmission Grating (HETG), astronomers were able to resolve the X-ray spectrum from the

  12. Map of critical raw material deposits in Europe

    NASA Astrophysics Data System (ADS)

    Guillaume, Bertrand

    2016-04-01

    Map of critical raw material deposits in Europe Guillaume BERTRAND1, Daniel CASSARD1, Nikolaos ARVANITIDIS2, Gerry STANLEY3 and the EuroGeoSurvey Mineral Resources Expert Group4. 1 - Bureau de Recherches Géologiques et Minières (BRGM), Georesources Divison, 3 avenue Claude Guillemin, 45060 Orléans cedex 2, FRANCE. 2 - Sveriges Geologiska Undersökning (SGU), Box 670, SE-751 28, Uppsala, SWEDEN 3 - Geological Survey of Ireland (GSI), Beggars Bush, Haddington Road, Dublin D04 K7X4, IRELAND 4 - EuroGeoSurveys, Rue Joseph II 36-38, 1000 Brussels, BELGIUM The Critical Raw Material (CRM) Deposit Map of Europe, prepared by EuroGeoSurvey's Mineral Resources Expert Group (MREG), shows European mineral deposits from the ProMine Mineral Deposit database containing critical commodities, according to the 2014 list of critical raw materials of the European Commission. EuroGeoSurveys (EGS), The Geological Surveys of Europe, is a not-for-profit organization representing 37 National Geological Surveys and some regional Geological Surveys in Europe. It provides the European Institutions with expert, independent, balanced and practical pan-European advice and information as an aid to problem-solving, policy development, regulatory and programme formulation in areas such as natural resources, energy and geo-hazards. The EGS MREG is actively involved in contributing to policy and strategy-making processes aimed at identifying, characterizing and safeguarding resource potential, especially for critical raw materials through data provision, research, technological development and innovation. The European Union aspires to reducing the import dependency of raw materials, especially CRM, that are essential to Europe's industries. In this respect, mineral resource information, data sharing and networking by European Geological Surveys is crucial. The Strategic Implementation Plan of the European Innovation Partnership on Raw Materials highlights the need for establishing and maintaining a

  13. PREFACE: 13th International Conference on Muon Spin Rotation, Relaxation and Resonance

    NASA Astrophysics Data System (ADS)

    2014-12-01

    submitted 227 contributions, which were intensively discussed during day and evening sessions. The scientific program was centered around invited talks from speakers outside the μSR community, who presented lectures on topics where μSR is giving or expected to give significant contributions. The invited speakers, covering various fields of interest, included Radu Coldea (Oxford, Quantum Magnetism), Claude- Henri Delmas (Bordeaux, Electro- and Solid State Chemistry), Dirk Johrendt (Munich, Iron Based Materials), Marc-Henri Julien (Grenoble, Cuprate Superconductors), Manfred Fiebig (Zürich, Multiferroics), Allan MacDonald (Austin, Topological Electronic States), Hidenori Takagi (Stuttgart and Tokyo, Transition Metal Oxides), and Jean-Marc Triscone (Geneva, Oxide Heterostructures). In addition to an overview about status and progress of the existing facilities in Europe, Canada and Japan, future projects and new ideas for μSR facilities in South Korea, China and the USA were presented. A special evening session was held to discuss about muon site and muon states calculations by DFT and other techniques. Several talks and posters can be found on the conference web page www.psi.ch/muSR2014. In a ceremony at the beginning of the conference, Roberto De Renzi from the University of Parma was awarded the 2014 Yamazaki Prize for muon science by the International Society for Muon Spin Spectroscopy (ISMS) for his sustained and exceptional contributions to the development of the muon spin relaxation technique to investigate magnetism and superconductivity and for promoting synergies between μSR and NMR. In the closing session Rob Kie (UBC Vancouver and TRIUMF) very effectively summarized the five days of meeting, while giving an enlightening personal impression. In the same session five best poster prizes were awarded and ISMS gave two prizes to young researchers presenting outstanding work at the conference. The conference organizers also on behalf of the entire μSR community are

  14. Comparison of 36Cl and 3He measurements in glacial surfaces on the tropical Altiplano (Cerro Tunupa volcano, 20°S)

    NASA Astrophysics Data System (ADS)

    Schimmelpfennig, Irene; Blard, Pierre-Henri; Lavé, Jérôme; Benedetti, Lucilla; Aster Team

    2016-04-01

    age is overestimated due to analytical complications. The results of this study show that combined 3He and 36Cl measurements are useful to detect geomorphological or analytical biases, and that they represent a high potential for the investigation of complex exposure histories in lithologies that lack quartz. Blard, P.-H., Lavé, J., Farley, K.A., Fornari, M., Jiménez, N., Ramirez, V., 2009. Late local glacial maximum in the Central Altiplano triggered by cold and locally-wet conditions during the paleolake Tauca episode (17-15 ka, Heinrich 1). Quat. Sci. Rev. 28, 3414-3427. Blard, P.-H., Lavé, J., Sylvestre, F., Placzek, C.J., Claude, C., Galy, V., Condom, T., Tibari, B., 2013. Cosmogenic 3He production rate in the high tropical Andes (3800 m, 20◦S): Implications for the local last glacial maximum. Earth Planet. Sci. Lett. 377-378, 260-275.

  15. Experience with Space Forums and Engineering Courses Organized for the Broad Dissemination of Space-related Information

    NASA Astrophysics Data System (ADS)

    Dessimoz, J.-D.; D'Aquino, U.; Gander, J.-G.; Sekler, J.

    2002-01-01

    Space technologies have been recognised as being of major importance for the welfare of our civilisation, not only in our industrially developed countries, but also for the world at large. Dating back to 1959, the Swiss Association for Astronautics (SRV; see http://srv-ch.org) has a long tradition of public communication in view of fostering support for space activities on a national scale. In recent years, the SRV has notably organised (or contributed for) about a dozen of Introductory Courses into Space Technology at different Swiss Universities of Applied Sciences (UAS), as well as set-up four Space Forums for reaching young people and the public at large. Space Forums are organised for younger students and the public at large. They have been so far organised at Zurich, with increasing impact. In 2002 the Space Forum is located at the "Technopark", a structure aiming at fostering technology transfers between universities and business, as well as to help creating start-up's. Contributions come from highly qualified speakers, such as "our" ESA astronaut Claude Nicollier, or scientists from leading research organisations. An exhibition is also organised, which presents space projects and material with very positive impact on the audience. As favourable by-product, the event tends to trigger further echoes in media (e.g. major press representatives and local radios). A good place is also made for outstanding contributions from young teenagers / enthusiastic supporters, which brings additional fresh views and effective communication channels for reaching the younger public. The Space techniques courses aim at a different public: engineering students and graduates. They are organised on a semester basis, with a frequency of about 1 or 2 courses per year; they are nearly always offered at different locations (most of the time at UAS) and can also be viewed as continuing education initiatives. Topics typically include a historical overview of space-related developments

  16. Ancient views on the hypothalamic-pituitary-thyroid axis: an historical and epistemological perspective.

    PubMed

    Toni, R

    2000-10-01

    The modern views on the anatomical and physiological interactions between the hypothalamus, pituitary and thyroid gland have emerged only in the last fifty years, although their historical roots may be found in a number of ancient and still not widely known ideas and observations. The regulation of energy body stores and temperature by the hypothalamic-pituitary-thyroid axis, for example, is a classical case of "fixitè du mileu interieur" in the sense originally suggested by Claude Bernard in the late 1800s, i.e. a homeostatic mechanism, but already 2100 year previously Aristotle had stated that the brain was necessary for the maintenance of body integrity by regulating food intake and behavior in relation to body temperature, the latter primarily determined by the heat of the blood. Five hundred years later Galen of Pergamon reported fundamental discoveries in the anatomy of the third ventricle region, including the location of the pituitary gland inside the sella turcica embodied in a vascular network, the rete mirabilis, and observed nerves adjoining the "soft flesh" in the neck, i.e. the thyroid gland. He first proposed that the energy of the body (the vital spirit) was carried through the arteries at the level of the rete mirabilis, where it was transformed into nerve impulse (the animal spirit), eventually transferred by the nerves to the periphery of the body, "glands" included, raising implicitly the possibility for a nervous influence over the thyroid activity. The Galenic model remained virtually unaltered up to the beginning of the 14th century, when the mediaeval anatomist Mondino de' Liuzzi put forth the idea that the thyroid gland interacted with the heat of the blood present in the internal carotid arteries due to their anatomical relation with the thyroid. This interaction enriched the vital spirit, i.e. the energy of the body, prior to its transformation into animal spirit, i.e. to nerve impulse directed to the periphery of the body. In addition

  17. Genetic risk profiles for cancer susceptibility and therapy response.

    PubMed

    Bartsch, Helmut; Dally, Heike; Popanda, Odilia; Risch, Angela; Schmezer, Peter

    2007-01-01

    beneficial effects were seen in non-small cell lung cancer (NSCLC) patients following gemcitabine and in SCLC patients following etoposide-based treatment. Several DNA repair parameters (polymorphisms, RNA expression, and DNA repair capacity) were measured in vitro in lymphocytes of patients before radiotherapy and correlated with the occurrence of acute side effects (radio-hypersensitivity). Our initial analysis of several repair gene variants in breast cancer patients (n = 446) who received radiotherapy revealed no association of single polymorphisms and the development of side effects (moist desquamation of the irradiated normal skin). The risk for this side effect was, however, strongly reduced in normal weight women carrying a combination of XRCC1 399Gln and APE1 148Glu alleles, indicating that these variants afford some protection against radio-hypersensitivity (Chang-Claude et al. 2005). Based on these data we conclude that specific metabolic and DNA repair gene variants can affect cancer risk and therapy outcome. Predisposition to hereditary cancer syndromes is dominated by the strong effects of some high-penetrance tumor susceptibility genes, while predisposition to sporadic cancer is influenced by the combination of multiple low-penetrance genes, of which as a major challenge, many disease-relevant combinations remain to be identified. Before translating these findings into clinical use and application for public health measures, large population-based studies and validation of the results will be required. PMID:17302182

  18. Hubble Space Telescope: The Telescope, the Observations & the Servicing Mission

    NASA Astrophysics Data System (ADS)

    1999-11-01

    Hubble's success is the advantage of being in orbit, beyond the Earth's atmosphere. From there it enjoys a crystal-clear view of the universe - without clouds and atmospheric disturbances to blur its vision. European astronomer Guido De Marchi from ESO in Munich has been using Hubble since the early days of the project. He explains: "HST can see the faintest and smallest details and lets us study the stars with great accuracy, even where they are packed together - just as with those in the centre of our Galaxy". Dieter Reimers from Hamburg Observatory adds: "HST has capabilities to see ultraviolet light, which is not possible from the ground due to the blocking effect of the atmosphere. And this is really vital to our work, the main aim of which is to discover the chemical composition of the Universe." The Servicing Missions In the early plans for telescope operations, maintenance visits were to have been made every 2.5 years. And every five years HST should have been transported back to the ground for thorough overhaul. This plan has changed somewhat over time and a servicing scheme, which includes Space Shuttle Servicing Missions every three years, was decided upon. The two first Servicing Missions, in December 1993 (STS-61) and February 1997 (STS-82) respectively, were very successful. In the first three years of operations HST did not meet expectations because its primary mirror was 2 microns too flat at the edge. The first Servicing Mission in 1993 (on which the European astronaut Claude Nicollier flew) dealt with this problem by installing a new instrument with corrective optics (COSTAR - Corrective Optics Space Telescope Axial Replacement). With this pair of "glasses" HST's golden age began. The images were as sharp as originally hoped and astonishing new results started to emerge on a regular basis. The first Servicing Mission also replaced the solar panels and installed a new camera (Wide Field and Planetary Camera 2 - WFPC2). The High-Speed Photometer (HSP) was

  19. Fluvial depositional environment evolving into deltaic setting with marine influences in the buntsandstein of northern vosges (France)

    NASA Astrophysics Data System (ADS)

    Gall, Jean-Claude

    supersaturation of stagnant waters with time. The fluvial environment persists up to the lower part of the Grès à Voltzia where the progression of the sea towards the west gives rise to a close intertonguing of fluvial and marine influences in a deltaic setting. Lenticular sandstone bodies are laid down as stream mouth bars at the end of the distributary channels and as river bars in the watercourses during both normal and flood discharge. Silty-clayey sediments settle out in stagnant water in restricted ponds, pools and puddles as well as in extensive veneers of shallow water in the overbank plain between the streams. Carbonate-bearing deposits originate in the coastal littoral mud flat, marsh seam, beach belt and tidal flat. The Grès à Voltzia has the greatest palaeoenvironmental and palaeoecological significance in the Buntsandstein of the Northern Vosges due to the occurrence of a wealth of extraordinarily well-preserved plant and animal fossils (having been recovered by Louis Grauvogel during almost 50 years and since abt. 25 years by Jean-Claude Gall). The rich suite of faunal and floral elements includes aquatic invertebrates, terrestrial animals and continental plants. The aquatic invertebrate fauna lives in fresh lakes and brackish ponds in the overbank plain and in brackish lagoons in the coastal seam as well as in hypersaline and euhaline marginal marine waters. The terrestrial plants colonize both dry and wet substrates, and the continental fauna consists of mainly arthropods, amphibians and reptiles inhabiting the levee zones of standing and flowing waters and strolling across the desiccated flats. The marine euryhaline association of invertebrates is with time replaced by a stenohaline community, and the deltaic plain of the Grès à Voltzia is finally inundated by a pellicular transgression representing the first stage of the Muschelkalk sea setting an end to Buntsandstein continental deposition.

  20. [Man and his fellow-creatures under ethical aspects].

    PubMed

    Teutsch, Gotthard M

    2005-01-01

    It is for reasons of age I will have to terminate my work at the Literary Review in the form developed since 1995. The report is being reduced to a concentration of ethically relevant reviews as exemplified in the fourth-quarter issue of ALTEX. This is to ascertain that essential developments in this field will not be overlooked. Insofar, the Literary Review will be continued under the heading "New literature concerning topics of animal ethics". The more central topics of animal ethics are being "used up" the more new questions are being formulated. Thus it was that during the last few years the plant-world, long neglected, was rediscovered and received attention through the publication of important works. Another recent discovery concerns itself with "cognitive ethology" which developed out of the critique of behaviourism and which is dealt with in a separate chapter in this issue. But there is also a "classic" of ethics who has been reviewed and interpreted anew repeatedly. In her book "Albert Schweitzer, a prophet of medical ethics", Heike Baranzke describes Schweitzer's ethics as not sentimental or nostalgic but rather as a radically modern stance, committed to the enlightenment. Manuel Schneider, also, conveys a comprehensive view of Albert Schweitzer's ethics in "Life in the middle of life - the relevance of the ethics of Albert Schweitzer", a book edited by Altner, Frambach, Gottwald and himself in 2005. For this, in particular, he derives a possibility of a physiocentric ethics. By contrast, Beate Weinzierl approaches Schweitzer on a complete personal and human level in "Yearning for nature - access to inner and outer nature with Albert Schweitzer". Wolfgang Senz is undertaking a critical appreciation of Albert Schweitzer's concept of "life" and this, foremost, in the light of Schweitzer's rejection of the Cartesian "I am". In the end, Jean Claude Wolf cannot manage without citing Schweitzer either, referring to him in his not accepting the (western) world

  1. BepiColombo mission to be presented to the media

    NASA Astrophysics Data System (ADS)

    2008-01-01

    After a competitive phase started in 2001, ESA has awarded Astrium the prime contract to build BepiColombo. The contract signature ceremony will take place in presence of the Prime Minister of Baden Württemberg (Germany), Dr. Guenther Oettinger, and will mark the kick-off of the industrial development of the spacecraft. BepiColombo will be launched in 2013. It consists of two spacecraft - an orbiter for planetary investigation, led by ESA, and one for magnetospheric studies, led by the Japan Aerospace Exploration Agency (JAXA). The satellite duo will reach Mercury in 2019 after a six-year journey towards the inner Solar System, to make the most extensive and detailed study of Mercury ever attempted. The press event will feature a thorough presentation of the mission and its objectives, as well as the technical challenges that Astrium will have to address. Such challenges derive from the difficulty of reaching, surviving and operating in the harsh environment of a planet so close to Sun, making of BepiColombo one of the most complex long-term planetary projects undertaken by ESA so far. Media interested to attend are invited to register by the reply form attached below. Visit of Prime Minister Guenther Oettinger and BepiColombo Contract Signature Event programme 18 January 2008, h 10:30 Astrium Friedrichshafen, Germany Claude-Dornier-Straße, 88090 Immenstaad Building 8, Room "Meersburg" 10:30 Check-in 11:00 Welcome and introduction, Uwe Minne, Astrium, Director of Earth Observation and Science, Head of Friedrichshafen Site 11:05 BepiColombo in the context of the ESA Science Programme, Jacques Louet, ESA Head of Science Projects Departments 11:10 BepiColombo's scientific objectives, Johannes Benkhoff, ESA, BepiColombo Project Scientist 11:20 The BepiColombo mission, Jan van Casteren, ESA, BepiColombo Project Manager 11:30 BepiColombo's technical challenges, Rainer Best, Astrium, BepiColombo Project Manager 11:40 Q&A 12:00 Buffet lunch 13:00 Arrival of Prime

  2. Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial

    PubMed Central

    Sagara, Issaka; Beavogui, Abdoul Habib; Zongo, Issaka; Soulama, Issiaka; Borghini-Fuhrer, Isabelle; Fofana, Bakary; Camara, Daouda; Somé, Anyirékun F; Coulibaly, Aboubacar S; Traore, Oumar B; Dara, Niawanlou; Kabore, Moïse J T; Thera, Ismaila; Compaore, Yves D; Sylla, Malick Minkael; Nikiema, Frederic; Diallo, Mamadou Saliou; Dicko, Alassane; Gil, Jose Pedro; Borrmann, Steffen; Duparc, Stephan; Miller, Robert M; Doumbo, Ogobara K; Shin, Jangsik; Bjorkman, Anders; Ouedraogo, Jean-Bosco; Sirima, Sodiomon B; Djimdé, Abdoulaye A

    2016-01-01

    with PCR-confirmed new infections, ACPR was similar on treatment and re-treatment and greater than 95% at day 28 and greater than 91% at day 42 in both treatment groups. Interpretation The findings that pyronaridine-artesunate safety and efficacy were similar on first malaria treatment versus re-treatment of subsequent episodes lend support for the wider access to pyronaridine-artesunate as an alternative artemisinin-based combination treatment for malaria in sub-Saharan Africa. Funding European and Developing Countries Clinical Trial Partnership, Medicines for Malaria Venture (Geneva, Switzerland), UK Medical Research Council, Swedish International Development Cooperation Agency, German Ministry for Education and Research, University Claude Bernard (Lyon, France), Malaria Research and Training Centre (Bamako, Mali), Centre National de Recherche et de Formation sur le Paludisme (Burkina Faso), Institut de Recherche en Sciences de la Santé (Bobo-Dioulasso, Burkina Faso), and Centre National de Formation et de Recherche en Santé Rurale (Republic of Guinea). PMID:26601738

  3. PREFACE: Symmetries and integrability of difference equations Symmetries and integrability of difference equations

    NASA Astrophysics Data System (ADS)

    Levi, Decio; Olver, Peter; Thomova, Zora; Winternitz, Pavel

    2009-11-01

    meeting with the name `Symmetries and Integrability of Discrete Equations (SIDE)' was held in Estérel, Québec, Canada. This was organized by D Levi, P Winternitz and L Vinet. After the success of the first meeting the scientific community decided to hold bi-annual SIDE meetings. They were held in 1996 at the University of Kent (UK), 1998 in Sabaudia (Italy), 2000 at the University of Tokyo (Japan), 2002 in Giens (France), 2004 in Helsinki (Finland) and in 2006 at the University of Melbourne (Australia). In 2008 the SIDE 8 meeting was again organized near Montreal, in Ste-Adèle, Québec, Canada. The SIDE 8 International Advisory Committee (also the SIDE steering committee) consisted of Frank Nijhoff, Alexander Bobenko, Basil Grammaticos, Jarmo Hietarinta, Nalini Joshi, Decio Levi, Vassilis Papageorgiou, Junkichi Satsuma, Yuri Suris, Claude Vialet and Pavel Winternitz. The local organizing committee consisted of Pavel Winternitz, John Harnad, Véronique Hussin, Decio Levi, Peter Olver and Luc Vinet. Financial support came from the Centre de Recherches Mathématiques in Montreal and the National Science Foundation (through the University of Minnesota). Proceedings of the first three SIDE meetings were published in the LMS Lecture Note series. Since 2000 the emphasis has been on publishing selected refereed articles in response to a general call for papers issued after the conference. This allows for a wider author base, since the call for papers is not restricted to conference participants. The SIDE topics thus are represented in special issues of Journal of Physics A: Mathematical and General 34 (48) and Journal of Physics A: Mathematical and Theoretical, 40 (42) (SIDE 4 and SIDE 7, respectively), Journal of Nonlinear Mathematical Physics 10 (Suppl. 2) and 12 (Suppl. 2) (SIDE 5 and SIDE 6 respectively). The SIDE 8 meeting was organized around several topics and the contributions to this special issue reflect the diversity presented during the meeting. The papers

  4. Dark Matter Reality Check: Chandra Casts Cloud On Alternative Theory

    NASA Astrophysics Data System (ADS)

    2002-10-01

    has successfully distinguished dark matter from MOND. The researchers also found that the Chandra data fit predictions of the cold dark matter theories, according to which dark matter consists of slowly moving particles, which interact with each other and "normal" matter only through gravity. Other forms of dark matter, such as self-interacting dark matter, and cold molecular dark matter, are not consistent with the observation in that they require a dark matter halo that is too round or too flat, respectively. "Chandra's ability to precisely identify and locate the point-like sources contaminating the diffuse emission in the X-ray image was absolutely essential," said Buote. "Only then could we make accurate measurements of the shape and orientation of the X-ray image contours." The conclusion from the Chandra data that NGC 720 possesses a dark matter halo assumes that the hot gas cloud has not been unduly disturbed by collisions or mergers with other galaxies in the last 100 million years. The lack of evidence of such activity indicates that this assumption is valid. Chandra observed NGC 720, which is about 80 million light years from Earth, for 11 hours with the Advanced CCD Imaging Spectrometer (ACIS). Other members of the team include Tesla Jeltema and Claude Canizares of Massachusetts Institute of Technology (MIT) in Cambridge, and Gordon Garmire of Pennsylvania State University in University Park. Penn State and MIT developed the instrument for NASA. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program, and TRW, Inc., Redondo Beach, Calif., is the prime contractor for the spacecraft. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, Mass.

  5. PREFACE: International Conference on Many Particle Spectroscopy of Atoms, Molecules, Clusters and Surfaces

    NASA Astrophysics Data System (ADS)

    Dowek, Danielle; Bennani, Azzedine; Lablanquie, Pascal; Maquet, Alfred

    2008-12-01

    The 2008 edition of the International Conference on Many Particle Spectroscopy of Atoms, Molecules, Clusters and Surfaces was held in Paris from 30 June to 2 July 2008. This biennial conference alternates with the International Symposium on (e,2e), Double Photoionization and Related Topics which is a satellite of the International Conference on Photonic, Electronic and Atomic Collisions (ICPEAC) conference. Over 110 participants from 20 countries gathered to examine the latest developments in the field of radiation interactions with matter. These include electron-electron correlation effects in excitation and in single and multiple ionization of atoms, molecules, clusters and surfaces with various projectiles: electrons, photons and ions. The present proceedings gathers the contributions of invited speakers and is intended to provide a detailed state-of-the-art account of the various facets of the field. Special thanks are due to Université Paris Sud XI, CNRS, and the laboratories LCAM, LIXAM and LCPMR which provided financial support for the organization of the conference. We are also grateful to the contribution of the companies Varian and RoentDek Handels GmbH. Guest Editors: Danielle Dowek and Azzedine Bennani LCAM, Université Paris Sud XI, France Pascal Lablanquie and Alfred Maquet LCPMR, Université Pierre et Marie Curie, Paris, France INTERNATIONAL SCIENTIFIC COMMITTEE Lorenzo Avaldi, (Italy) Alexei Grum Grzhimailo, (Russia) Klaus Bartschat, (USA) Nikolai Kabachnik, (Russia) Jamal Berakdar, (Germany) Birgit Lohmann, (Australia) Nora Berrah, (USA) Don H Madison, (USA) Michael Brunger, (Australia) Francis Penent, (France) Albert Crowe, (UK) Bernard Piraux, (Belgium) Claude Dal Cappello, (France) Roberto Rivarola, (Argentina) JingKang Deng, (China) Emma Sokkel, (Ireland) Alexander Dorn, (Germany) Giovanni Stefani, (Italy) Reinhardt Dorner, (Germany) Noboru Watanabe, (Japan) François Frémont, (France) LOCAL ORGANIZING COMMITTEE Azzedine BENNANI (Chair

  6. [The vitalism of Paul-Joseph Barthez (1734-1806)].

    PubMed

    Han, Hee Jin

    2010-06-30

    In The Logic of Life (1970), Francois Jacob (1920- ), Nobel Prize laureate in Physiology or Medicine (1965), proclaimed the end of vitalism based on the concept of life. More than two decades before this capital sentence condemning vitalism was pronounced, Georges Canguilhem (1904-1995), a French philosopher of medicine, already acknowledged that eighteenth-century vitalism was scientifically retrograde and politically reactionary or counter-revolutionary insofar as it was rooted in the animism of Georg Ernst Stahl (1660-1734). The negative preconception of the term 'vitalism' came to be established as an orthodox view, since Claude Bernard (1813-1878) unfairly criticized contemporary vitalism in order to propagate his idea of experimental medicine. An eminent evolutionary biologist like Ernst Mayr (1904-2005) still defended similar views in This is Biology (1997), arguing that if vitalists were decisive and convincing in their rejection of the Cartesian model (negative heuristics), however they were equally indecisive and unconvincing in their own explanatory endeavors (positive heuristics). Historically speaking, vitalists came to the forefront for their outstanding criticism of Cartesian mechanism and physicochemical reductionism, while their innovative concepts and theories were underestimated and received much less attention. Is it true that vitalism was merely a pseudo-science, representing a kind of romanticism or mysticism in biomedical science? Did vitalists lack any positive heuristics in their biomedical research? Above all, what was actually the so.called 'vitalism'? This paper aims to reveal the positive heuristics of vitalism defined by Paul.Joseph Barthez (1734-1806) who was the founder of the vitalist school of Montpellier. To this end, his work and idea are introduced with regard to the vying doctrines in physiology and medicine. At the moment when he taught at the medical school of Montpellier, his colleagues advocated the mechanism of Rene

  7. Climatic versus topographic forcing on the extend of major Alpine ice-caps

    NASA Astrophysics Data System (ADS)

    Salcher, Bernhard; Sternai, Pietro

    2015-04-01

    .e. after the mid-Pleistocene transition) show similar extensions. These new observations conflict with older stratigraphic models and no profound explanations have been found yet. Our aim is to explore these first-order feedback mechanisms impacting the growth and extend of Alpine ice shields through time and evolving topography by taking advantage of the comprehensive records and time constraints of glacial history available from the European Alps. Akçar, N., Ivy-Ochs, S., Alfimov, V., Claude, A., Graf, H.R., Dehnert, A., Kubik, P.W., Rahn, M., Kuhlemann, J., Schlüchter, C. (2014): The first major incision of the Swiss Deckenschotter landscape. Swiss J Geosci. DOI 10.1007/s00015-014-0176-6. Pedersen, V., Egholm, D.L. (2013): Glaciations in response to climate variations preconditioned by evolving topography. Nature, 493, 207-210. Preusser, F. (2004): Towards a chronology of the Late Pleistocene in the northern Alpine Foreland. Boreas 33, 195-210.

  8. Animal models for human diseases.

    PubMed

    Rust, J H

    1982-01-01

    proposed that an aggressive invasive cancer of the dog that he had observed be used to study cancer in a generic sense. Other researchers who recognized the value of animals in medical research were Jenner, Claude Bernard, and Pasteur. The human can also serve as an animal model. Some of those situations are presented, and in all a common theme exists. There was no known animal model that could be used, and in some cases the situation has not changed today. In all cases the discoveries must be regarded as serendipitous. The state of the art of the pathology of laboratory animal diseases and neoplasia is unsatisfactory. There is much empirical speculation and little substance. Cancer studies with mice and rats as now conducted are of minimal value. Although a tradition of excellence in the use of animal models to help understand human disease has been established, much remains to be learned. PMID:7167364

  9. [The discovery of hypoglycemic sulfonamides].

    PubMed

    Loubatières-Mariani, Marie-Madeleine

    2007-01-01

    and structural analogs and investigated the mechanism involved in the hypoglycemia. These results are reported in his "Doctorat ès-Sciences" thesis (1946). He observed that 2254 RP was ineffective on glycemia in totally pancreatectomized dogs but was effective in partially pancreatectomized ones. The hypoglycemic effect in normal dog was dependent on the plasma sulfonamide concentration; this effect appeared whatever the route of administration and was unaffected by vagotomy. Furthermore, Loubatières performed cross-circulation experiments. In these experiments, the pancreatico-duodenal vein of a normal dog was anastomosed to the jugular vein of a receiver dog made diabetic by alloxan; in this case, the injection of 2254 RP into the donor induced a decrease in blood glucose levels in the receiver. In early 1946, Auguste Loubatières proposed that the hypoglycemic property of 2254 RP was due to its ability to stimulate insulin secretion through a direct action on pancreatic islets; he wrote in his thesis "A notre avis, le para-amino-benzène-sulfamido-isopropylthiodiazol (2254 RP) est donc un corps essentiellement insulino-sécréteur; son action s'exerce directement sur les îlots de Langerhans". He also proposed to use such hypoglycemic sulfonamides in certain forms of diabetes "que l'on peut qualifier de fonctionnels et qui sont la conséquence d'une paresse des mécanismes insulino-sécréteurs". In 1992, Jean-Claude Henquin demonstrated that the sequence of events triggered by 2254 RP at the level of islet beta-cells was similar to that induced by sulfonylureas of the first or second generation. Thus, the 2254 RP, proposed by Auguste Loubatières in the treatment of certain forms of diabetes, was the first of oral hypoglycemic sulfonamides currently used in the treatment of type 2 diabetes mellitus. PMID:17978743

  10. European astronaut selected for the third Hubble Space Telescope

    NASA Astrophysics Data System (ADS)

    1998-08-01

    The STS-104 crew will rendezvous with the orbiting Hubble Space Telescope, which is the size of a city bus, capture it using the Shuttle's Canadian robot arm and secure it in Columbia's payload bay. Then, working in teams of two, the four astronauts will leave the Shuttle's pressurised cabin and venture into the payload bay, performing a variety of tasks that will improve the productivity and reliability of the telescope. The four astronauts will perform a series of six "extravehicular" activities in the open space environment. Such activities are commonly called spacewalks, but this term does little justice to the considerable physical and mental efforts that astronauts need to make in doing the very demanding work involved. The Shuttle commander and pilot for this flight have not yet been appointed, but the four designated mission specialists begin training for the STS-104 mission immediately. "The ambitious nature of this mission, with its six spacewalks, made it important for the payload crew to begin training as early as possible," said David C. Leestma, NASA Director of Flight Crew Operations at the Johnson Space Center in Houston, to which Claude Nicollier is on resident assignment from ESA's European Astronaut Centre in Cologne, Germany, the home base of the European astronaut corps. The Hubble Space Telescope was launched into orbit in April 1990. It is one of the most capable optical telescopes available to astronomers today, producing images and spectral observations at the forefront of astronomy. The European Space Agency contributed a 15 share to the development of Hubble. One of the five scientific instruments on board, the Faint Object Camera, was built by a European industrial consortium made up of British Aerospace, Dornier and Matra under a contract with the European Space Agency. The solar arrays which provide Hubble with electrical power were manufactured by British Aerospace and Dornier. In its eight years of operation, the telescope has not

  11. PREFACE Preface

    NASA Astrophysics Data System (ADS)

    Bachor, Hans; Drummond, Peter; Hannaford, Peter

    2011-01-01

    The 22nd International Conference on Atomic Physics (ICAP 2010) was held from 25 to 30 July, 2010 in Cairns, Tropical North Queensland, Australia. This conference followed on from the series of highly successful biennial ICAP conferences held in Storrs, Innsbruck, Rio, Cambridge MA, Florence, Windsor, Amsterdam, Boulder, Munich, Ann Arbor, Paris, Tokyo, Seattle, Göteborg, Cambridge MA, Riga, Berkeley, Heidelberg, Boulder, Oxford and New York. ICAP 2010 was attended by 630 participants from 37 countries. The conference presented an outstanding program of papers covering the most recent advances in atomic physics, including atomic tests of fundamental physics and basic symmetries; precision measurements, including atomic clocks, atom interferometers and fundamental constants; ultracold gases and Bose-Einstein condensates; ultracold Fermi gases; ultracold molecules; quantum simulators with atoms and ions; few-body systems; ultrafast phenomena and free electron lasers; quantum information with atoms and ions; quantum optics and cavity QED with atoms; and hybrid and optomechanical systems. The papers in this Proceedings represent a collection of the invited talks. The conference program consisted of 48 invited talks presented in plenary sessions, including 10 'hot topic' talks highlighting the most recent advances in the field, and about 490 poster papers presented in three afternoon sessions. The program included talks by Nobel Laureates Claude Cohen-Tannoudji, Wolfgang Ketterle and Bill Phillips, a memorium talk commemorating the scientific life of Vladilen Letokhov, and an evening lecture by Alain Aspect on 'Wave particle duality for a single photon: quantum weirdness brought to light'. The conference was preceded by a two-day workshop in Cairns on Variation of Fundamental Constants and Violation of Fundamental Symmetries P, T(EDM), CPT, Lorentz Invariance, organised by the University of New South Wales; and three-day Student Workshop at Cape Tribulation, organized

  12. NSLS-II: Nonlinear Model Calibration for Synchrotrons

    SciTech Connect

    Bengtsson, J.

    2010-10-08

    This tech note is essentially a summary of a lecture we delivered to the Acc. Phys. Journal Club Apr, 2010. However, since the estimated accuracy of these methods has been naive and misleading in the field of particle accelerators, i.e., ignores the impact of noise, we will elaborate on this in some detail. A prerequisite for a calibration of the nonlinear Hamiltonian is that the quadratic part has been understood, i.e., that the linear optics for the real accelerator has been calibrated. For synchrotron light source operations, this problem has been solved by the interactive LOCO technique/tool (Linear Optics from Closed Orbits). Before that, in the context of hadron accelerators, it has been done by signal processing of turn-by-turn BPM data. We have outlined how to make a basic calibration of the nonlinear model for synchrotrons. In particular, we have shown how this was done for LEAR, CERN (antiprotons) in the mid-80s. Specifically, our accuracy for frequency estimation was {approx} 1 x 10{sup -5} for 1024 turns (to calibrate the linear optics) and {approx} 1 x 10{sup -4} for 256 turns for tune footprint and betatron spectrum. For a comparison, the estimated tune footprint for stable beam for NSLS-II is {approx}0.1. Since the transverse damping time is {approx}20 msec, i.e., {approx}4,000 turns. There is no fundamental difference for: antiprotons, protons, and electrons in this case. Because the estimated accuracy for these methods in the field of particle accelerators has been naive, i.e., ignoring the impact of noise, we have also derived explicit formula, from first principles, for a quantitative statement. For e.g. N = 256 and 5% noise we obtain {delta}{nu} {approx} 1 x 10{sup -5}. A comparison with the state-of-the-arts in e.g. telecomm and electrical engineering since the 60s is quite revealing. For example, Kalman filter (1960), crucial for the: Ranger, Mariner, and Apollo (including the Lunar Module) missions during the 60s. Or Claude Shannon et al

  13. Is these a link between eustatic variations, platform drowning, oceanic anoxic events, and ammonite faunal turnovers ? Case study of the Aptian sediments along the northern Tethyan margin

    NASA Astrophysics Data System (ADS)

    Pictet, Antoine; Föllmi, Karl; Spangenberg, Jorge

    2014-05-01

    appearance of Dufrenoyia, Eotetragonites, Aconoceras, Colombiceras, and other genera (Daupin, 2002; Dutour, 2005). A third drowning phase, reported from the latest early Aptian (late D. furcata zone), occurred with the establishment of a second emersion phase, characterised by a significant karstified discontinuity. Just above, organic-rich sediments were deposited. This third phase is marked by the complete disappearance of platforms in favour of marl deposits, and coincides with the emergence of the anoxic 'Niveau Noir level' which is considered as a document of an important phase of widespread dys- to anaerobic conditions within the Selli Episode (Föllmi, 2012). The ammonite fauna is marked by a second turnover with the replacement of Dufrenoyia, Cheloniceras, and Pseudohaploceras, by Epicheloniceras, Zucherella, Gabbioceras, and other genera (Daupin, 2002; Dutour, 2005). In conclusion, the combined effect of sea-level change and subsequent oceanic anoxia as the consequence of climatic change is a key element in the platform crises and associated important faunal turnover. References DAUPHIN L. (2002) Litho-, bio-, et chronostratigraphie comparées dans le bassin vocontien à l'Aptien. Phd Univ. des sciences et technologies - Lille I. DUTOUR, Y. (2005).- Biostratigraphie, évolution et renouvellements des ammonites de l'Aptien supérieur (Gargasien) du bassin vocontien (Sud-Est de la France).- Thèse Université Claude Bernard-Lyon 1, 302 p. (inedit) FÖLLMI, K.B. (2012).- Early Cretaceous life, climate and anoxia.- Cretaceous Research (2012), doi:10.1016/ j.cretres.2011.12.005 LARSON, R.L., ERBA, E., 1999. Onset of the mid-Cretaceous greenhouse in the BarremianeAptian: igneous events and the biological, sedimentary, and geochemical responses. Paleoceanography 14, 663-678.

  14. Magnetospheric accretion on the T Tauri star BP Tauri

    NASA Astrophysics Data System (ADS)

    Donati, J.-F.; Jardine, M. M.; Gregory, S. G.; Petit, P.; Paletou, F.; Bouvier, J.; Dougados, C.; Ménard, F.; Collier Cameron, A.; Harries, T. J.; Hussain, G. A. J.; Unruh, Y.; Morin, J.; Marsden, S. C.; Manset, N.; Aurière, M.; Catala, C.; Alecian, E.

    2008-05-01

    'Univers of the Centre National de la Recherche Scientifique of France (INSU/CNRS) and the University of Hawaii, while TBL is operated by CNRS/INSU. E-mail: donati@ast.obs-mip.fr (J-FD); mmj@st-andrews.ac.uk (MMJ); sg64@st-andrews.ac.uk (SGG); petit@ast.obs-mip.fr (PP); fpaletou@ast.obs-mip.fr (FP); jerome.bouvier@obs.ujf-grenoble.fr (JB); catherine.dougados@obs.ujf-grenoble.fr (CD); francois.menard@obs.ujf-grenoble.fr (FM); acc4@st-andrews.ac.uk (ACC); th@astro.ex.ac.uk (TJH); ghussain@eso.org (GAJH); y.unruh@imperial.ac.uk (YU); jmorin@ast.obs-mip.fr (JM); scm@aao.gov.au (SCM); manset@cfht.hawaii.edu (NM); auriere@ast.obs-mip.fr (MA); claude.catala@obspm.fr (CC); evelyne.alecian@obspm.fr (EA)

  15. Foreword

    NASA Astrophysics Data System (ADS)

    Boutron, Claude; Ferrari, Christophe

    2003-05-01

    thank the members of the organising committee and Jerome Nriagu (chairman of the 11th Conference) for helping us to put together the program of this conference. Also, very special thanks are due to Christine Echevet for her continuous and expert efforts to make the Grenoble Conference a success, and to various members of the Laboratoire de Glaciologie et Géophysique de l'Environnement, especially Jocelyne Roquemora. Special thanks are also due to the President of Grenoble Alpes Métropole and the Mayor of the City of Grenoble. Finally, we are very grateful to the various co-sponsors of the conference, especially the Centre National de la Recherche Scientifique (CNRS), the University Joseph Fourier of Grenoble, the Ministère des Affaires Étrangères, the Ministère de l'Écologie et du Développement Durable, the Agence de l'Environnement et de la Maîtrise de l'Énergie (ADEME), Grenoble Alpes Métropole (La Métro), the City of Grenoble, the Region Rhône-Alpes, the Conseil Général de l'Isère, the Association Minéraux, Métaux non ferreux, Santé, Environnement (AMSE), the University of Michigan and the Société Hydrotechnique de France (SHF). Claude BOUTRON and Christophe FERRARI - Conference Co-Chairmen 12th International Conference on Heavy Metals in the Environment, Grenoble, France, 26-30 May 2003 Préface C'est un grand plaisir pour nous d'accueillir la “12e Conférence Internationale sur les Métaux Lourds dans l'Environnement en France Grenoble, au coeur des Alpes. Cette conférence est la 12e du nom, après celles qui ont eu lieu avec beaucoup de succès à Toronto (1975), Londres (1979), Amsterdam (1981), Heidelberg (1983), Athènes (1985), La Nouvelle Orléans (1987), Genève (1989), Edimbourg (1991), Hambourg (1995) et Ann Arbor (2000). Grenoble est l'une des principales ville d'Europe pour la recherche scientifique avec un très grand nombre de chercheurs dans des domaines trés variés, notamment en Physique et Chimie, Mathématiques et

  16. New Adaptive Optics Technique Demonstrated

    NASA Astrophysics Data System (ADS)

    2007-03-01

    four AO systems for the interferometric mode of the VLT). ESO PR Photo 19b/07 ESO PR Photo 19b/07 The Globular Cluster Omega Centauri (MAD/VLT) Present AO systems can only correct the effect of atmospheric turbulence in a relative small region of the sky - typically 15 arcseconds, the correction degrading very quickly when moving away from the central axis. Engineers have therefore developed new techniques to overcome this limitation, one of which is multi-conjugate adaptive optics (MCAO). At the end of 2003, ESO, together with partners in Italy and Portugal, started the development of a MCAO Demonstrator, named MAD. "The aim of MAD is to prove the feasibility and performances of new adaptive optics techniques, such as MCAO, meant to work on large fields of view and to serve as a very powerful test tool in understanding some of the critical issues that will determine the development of future instruments, for both the VLT and the Extremely Large Telescopes," said Norbert Hubin, head of the AO group at ESO. MAD is an advanced generation adaptive optics system, capable of compensating for the atmospheric turbulence disturbance on a large field of view (FoV) on the sky. It can successfully correct a 1-2 arcmin FoV, much larger than the ~15 arcsec typically provided by the existing adaptive optics facilities. MAD was fully developed and extensively characterized by ESO using a dedicated turbulence generator (MAPS, Multi Atmospheric Phase screens and Stars) able to reproduce in the laboratory the temporal evolution and the vertical structure of the turbulence observed at the Observatory. ESO PR Photo 19c/07 ESO PR Photo 19c/07 The MCAO Concept MAD was then disassembled and shipped to Paranal for re-integration at the Nasmyth Visitor focus of UT3. The integration took about 1 month, after which the system was ready for daylight testing and further characterization. "On the night of 25 March, we could successfully close the first MCAO loop on the open cluster NGC 3293," said

  17. EDITORIAL Proceedings of the XIV International Conference on Small-Angle Scattering, SAS-2009

    NASA Astrophysics Data System (ADS)

    Ungar, Goran; Heenan, Richard

    2010-10-01

    papers by Felisa Berenguer and the Diamond/UCL team (012004) and by Birgit Fischer and the DESY/Rostock team (012026). The former describe their effort to reconstruct the image of wet collagen tissue from the speckled pattern of a narrow transmitted beam and complement the results of imaging by scanning SAXS. Fischer et al. utilize the coherence of the X-ray beam in the photon correlation spectroscopy mode to determine the dynamic structure factor, from which the q-dependence of the relaxation times was determined for solutions of charged colloidal particles. The nature of particle motion was thus determined, i.e. ballistic at lower concentrations vs. restricted by 'caging' at higher concentrations. The use of scanning microbeam diffraction was also described in the paper by the group of Peter Fratzl (012031), who combined it with tilting the sample in order to obtain what is referred to as 3D SAXS. In this way the orientation distribution of crystallites in callus tissue during bone fracture healing can be explored. Naoto Yagi et al. (012024) used microbeam SAXS and WAXS to study dental enamel crystals in a caries lesion. Anomalous, or resonant, X-ray scattering at low angles (ASAXS) was employed by Guenter Goerigk and Norbert Mattern (Jülich/Dresden) (012022) to study phase separation in the ternary alloy Ni-Nb-Y. Experiments were performed near the K-absorption edges of the three elements and the authors describe how they determined quantitatively the chemical composition of the different separate phases as well as short-range concentration fluctuations during spinodal decomposition. For organic materials, where heavy atoms are not present, typically sulphur would be replaced by Se, so ASAXS could be performed near the Se K-edge. However, Masashi Handa et al. from the University of Tokyo report in paper 012006 a feasibility study of using sulphur itself as the label. They deal with the challenging task of using low-energy X-rays at the sulphur K-edge. Alexandra

  18. PREFACE: XXXth International Colloquium on Group Theoretical Methods in Physics (ICGTMP) (Group30)

    NASA Astrophysics Data System (ADS)

    Brackx, Fred; De Schepper, Hennie; Van der Jeugt, Joris

    2015-04-01

    panel discussion on recent advances and future challenges in group theoretical methods in physics was held on Wednesday morning. The panel members were: Maia Angelova, Heinz-Dietrich Doebner, Jean-Pierre Gazeau, Norbert Hounkonnou, Peter Olver and Luc Vinet, with Willard Miller Jr. as moderator. In this discussion, the importance of "symmetry" in physics (and other sciences) was emphasized, and some challenges were made explicit. On Wednesday evening there was a separate ceremony in the Aula Academica (the "University Palace") of Ghent University, for the presentation of the 2014 Wigner Medal and Hermann Weyl Prize. The Hermann Weyl Prize was established in 2000 to provide recognition for young scientists having performed original work of significant scientific quality in the area of the understanding of physics through symmetries. The 2014 Hermann Weyl Prize was awarded to Yuji Tachikawa (Tokyo University). He is praised for his outstanding contributions to the understanding of supersymmetric quantum field theories and in particular, to the discovery of the Alday-Gaiotto-Tachikawa correspondence that has led to spectacular advances in both mathematics and quantum physics. The Wigner Medal, established in 1978, is an award designed "to recognize outstanding contributions to the understanding of physics through Group Theory", and can be considered as a "lifetime achievement award". It was awarded to Joshua Zak (Technion, Haifa, Israel) for his discovery of the magnetic translation group and the phase and transform that bear his name. In his work, the relationship between mathematics and physics could hardly be closer, with mathematicians being familiar with the "Zak transform" and physicists with the "Zak phase", both concepts originating in group theory. The ceremony was graced by a saxophone quintet, "Sax Obsession", and followed by a reception in the adjacent Peristylium. The social programme included a variety of events. On Monday evening, the welcome address by

  19. The Coming of Age of Adaptive Optics

    NASA Astrophysics Data System (ADS)

    1995-10-01

    hundred times per second, allowing to achieve very nearly the theoretical image sharpness in the mid-infrared wavelength region. Closer to the visible spectral region, images have been obtained at wavelength 1.5 microns which are only 0.12 arcseconds wide. Under the leadership of Norbert Hubin at the ESO Headquarters in Garching, a team of astronomers and engineers is now in the process of designing the Nasmyth Adaptive Optics System (NAOS) that will be used at the Very Large Telescope (VLT). It will use a mirror with about 250 supports. Following testing in the second half of 1998, it is expected that the first NAOS device will be mounted on the first 8.2-metre VLT unit telescope in early 1999. Notes: [1] The Topical Meeting on Adaptive Optics sponsored by the Optical Society of America and the European Southern Observatory was held on the premises of the Munich Technical University in Garching, on October 2--6, 1995. [2] See ESO Press Releases 06/89 of 24 October 1989 and 05/90 of 25 May 1990.

  20. Back on Track

    NASA Astrophysics Data System (ADS)

    2007-06-01

    An artificial, laser-fed star now shines regularly over the sky of Paranal, home of ESO's Very Large Telescope, one of the world's most advanced large ground-based telescopes. This system provides assistance for the adaptive optics instruments on the VLT and so allows astronomers to obtain images free from the blurring effect of the atmosphere, regardless of the brightness and the location on the sky of the observed target. Now that it is routinely offered by the observatory, the skies seem much sharper to astronomers. In order to counteract the blurring effect of Earth's atmosphere, astronomers use the adaptive optics technique. This requires, however, a nearby reference star that has to be relatively bright, thereby limiting the area of the sky that can be surveyed. To surmount this limitation, astronomers now use at Paranal a powerful laser that creates an artificial star, where and when they need it. Two of the Adaptive Optics (AO) science instruments at the Paranal observatory, NACO and SINFONI, have been upgraded to work with the recently installed Laser Guide Star (LGS; see ESO 07/06) and have delivered their first scientific results. This achievement opens astronomers' access to a wealth of new targets to be studied under the sharp eyes of AO. "These unique results underline the advantage of using a Laser Guide Star with Adaptive Optics instruments, since they could not be obtained with Natural Guide Stars," says Norbert Hubin, head of the Adaptive Optics group at ESO. "This is also a crucial milestone towards the multi-laser systems ESO is designing for the VLT and the future E-ELT" (see e.g. ESO 19/07). ESO PR Photo 27a/07 ESO PR Photo 27a/07 An Ultra Luminous Merger (NACO-LGS/VLT) The Laser Guide Star System installed at Paranal uses the PARSEC dye laser developed by MPE-Garching and MPIA-Heidelberg, while the launch telescope and the laser laboratory was developed by ESO. "It is great to see the whole system working so well together," emphasises Richard

  1. Free from the Atmosphere

    NASA Astrophysics Data System (ADS)

    2007-06-01

    An artificial, laser-fed star now shines regularly over the sky of Paranal, home of ESO's Very Large Telescope, one of the world's most advanced large ground-based telescopes. This system provides assistance for the adaptive optics instruments on the VLT and so allows astronomers to obtain images free from the blurring effect of the atmosphere, regardless of the brightness and the location on the sky of the observed target. Now that it is routinely offered by the observatory, the skies seem much sharper to astronomers. In order to counteract the blurring effect of Earth's atmosphere, astronomers use the adaptive optics technique. This requires, however, a nearby reference star that has to be relatively bright, thereby limiting the area of the sky that can be surveyed. To surmount this limitation, astronomers now use at Paranal a powerful laser that creates an artificial star, where and when they need it. Two of the Adaptive Optics (AO) science instruments at the Paranal observatory, NACO and SINFONI, have been upgraded to work with the recently installed Laser Guide Star (LGS; see ESO 07/06) and have delivered their first scientific results. This achievement opens astronomers' access to a wealth of new targets to be studied under the sharp eyes of AO. "These unique results underline the advantage of using a Laser Guide Star with Adaptive Optics instruments, since they could not be obtained with Natural Guide Stars," says Norbert Hubin, head of the Adaptive Optics group at ESO. "This is also a crucial milestone towards the multi-laser systems ESO is designing for the VLT and the future E-ELT" (see e.g. ESO 19/07). ESO PR Photo 27a/07 ESO PR Photo 27a/07 An Ultra Luminous Merger (NACO-LGS/VLT) The Laser Guide Star System installed at Paranal uses the PARSEC dye laser developed by MPE-Garching and MPIA-Heidelberg, while the launch telescope and the laser laboratory was developed by ESO. "It is great to see the whole system working so well together," emphasises Richard

  2. PREFACE: Eighth International Conference on Dissociative Recombination (DR2010)

    NASA Astrophysics Data System (ADS)

    Guberman, Steven L.; Orel, Ann E.

    2011-07-01

    Lake Louise, Alberta, Canada in May, 1988 [2] and was followed in May 1992 [3] at L'Abbaye de Saint Jacut de la Mer, Brittany, France, in May, 1995 [4] at Ein Gedi, Israel, in June 1999 [5] on the island of Nässlingen in the Stockholm archipelago, Sweden, in August, 2001 [6] at Chicago, USA, in July, 2004 [7] at the Alte Mälzerei, Mosbach, Germany and in July, 2007 [8] at the Resort d'Amelander Kaap on the island of Ameland, The Netherlands. All papers from the last two conferences and this conference are freely available at http://iopscience.iop.org/1742-6596. In keeping with the tradition of prior DR conferences, all papers in this volume have been refereed. Our thanks go to the referees for their efforts. Travel support for conference participants was provided by NSF grant ATM-0838061 and NASA grant NNX09AQ73G to SLG. We thank Priscilla Kujawski for proofreading the Dedication. Steven L GubermanAnn E OrelEditors Conference photograph Participants of the 8th International Conference on Dissociative Recombination: Theory, Experiments and Applications. 1. Stephen Pratt18. Randy Vane35. Robert Continetti 2. Chris Greene19. Claude Krantz36. Henrik Buhr 3. Bastiaan Braams20. Xavier Urbain37. Mats Larsson 4. Ed Grant21. Hidekazu Takagi38. Dirk Schwalm 5. Christian Nordhorn22. Brian Mitchell39. Evelyne Roueff 6. Steen Brønsted Nielsen23. Andreas Wolf40. Pascal Pernot 7. Dermot Madden24. Daren Stotler41. Stefan Rosén 8. Radek Plašil25. Slava Kokoouline42. Rainer Johnsen 9. Daniel Savin26. David Schultz43. Xiaohong Cai 10. Jonathan Tennyson27. Mourad Telmini44. Dan Haxton 11. Peet Hickman28. Ruth Malenda45. Åsa Larson 12. Michael Fogle29. Slim Chourou46. Dahbia Talbi 13. Waffeu Tamo Francois Oliver30. Petr Dohnal47. Ann Orel 14. Christian Jungen31. Julia Stützel48. Steven Guberman 15. Ilya Fabrikant32. Ioan Schneider49. Jane Fox 16. Wolf Geppert33. Nicholas Shuman50. Richard Thomas 17. Oldřich Novotný34. Holger Kreckel51. Fangfang Ruan

  3. Preface

    NASA Astrophysics Data System (ADS)

    Aspect, Alain

    2002-06-01

    é des conférences invitées et des communications par affiches. Pour la première fois, un forum pour l'emploi a été mis en place afin de permettre aux doctorants et post-doctorants de nouer des premiers contacts avec leurs futurs employeurs. Enfin, COLOQ 7 a été clôturé par une conférence de Claude Cohen-Tannoudji, ouverte au public, qui a enthousiasmé non seulement les participants du colloque, mais aussi les étudiants et les lycéens de Rennes, qui avaient été conviés avec leurs enseignants. La réussite de cette manifestation est due, avant tout, à la qualité scientifique des présentations, mais elle repose aussi sur l'action conjuguée des comités d'organisation national et local, au généreux soutien des diverses instances publiques nationales, régionales, locales, et à la forte participation des sociétés industrielles du secteur optoélectronique et laser qui nous ont permis de maintenir les frais d'inscription à un niveau particulièrement raisonnable ; en particulier pour les jeunes. Que tous soient ici remerciés, en particulier le comité local qui a su, au delà d'une organisation impeccable, nous faire apprécier la chaleur de l'accueil breton !

  4. List of Participants

    NASA Astrophysics Data System (ADS)

    2011-09-01

    AbeTakashiUniversity of Tokyotabe@nt.phys.s.u-tokyo.ac.jp AmusiaMironRacah Institute of Physics, Jerusalemamusia@vms.huji.ac.il BaldoMarcelloINFN Cataniabaldo@ct.infn.it BansalManiePanjab University, Chandigarhbansalmanni@gmail.com BarrancoFranciscoUniversity of Sevillebarranco@us.es BertschGeorgeUniversity of Washington, Seattlebertsch@u.washington.edu BhagwatAmeeyaCBS Mumbaiameeya@kth.se BorderieBernardIPN Orsayborderie@ipno.in2p3.fr CarbonellJaumeLPSC Grenoblejaume.carbonell@lpsc.in2p3.fr CarlsonJoeLos Alamos National Laboratorycarlson@lanl.gov ColòGianlucaINFN - Università degli Studi di Milanocolo@mi.infn.it DanielewiczPawelNSCL, Michigan State Universitydanielewicz@nscl.msu.edu DescouvemontPierreUniversité Libre de Bruxellespdesc@ulb.ac.be Dohet-EralyJérémyUniversité Libre de Bruxellesjdoheter@ulb.ac.be DraayerJerryLouisiana State Universitydraayer@lsu.edu DufourMarianneIPHC, Université de Strasbourgmarianne.dufour@ires.in2p3.fr DuguetThomasCEA Saclaythomas.duguet@cea.fr DukelskyJorgeCSIC Madriddukelsky@iem.cfmac.csic.es EbranJean-PaulCEA-DAM, Arpajonebran@ipno.in2p3.fr FreerMartinUniversity of Birminghamm.freer@bham.ac.uk FujiiShinichiroUniversity of Tokyosfujii@cns.s.u-tokyo.ac.jp FunakiYasuroRIKEN Nishina Center, Wakofunaki@riken.jp GrassoMarcellaIPN Orsaygrasso@ipno.in2p3.fr HaginoKouichiTohoku Universityhagino@nucl.phys.tohoku.ac.jp HansenHubertUniversité Claude Bernard Lyon 1hansen@ipnl.in2p3.fr HolzmannMarkusLPMMC Grenoblemarkus@lptl.jussieu.fr HoriuchiHisashiRCNP, Osaka Universityhoriuchi@rcnp.osaka-u.ac.jp HoriuchiWataruGSI Darmstadtw.horiuchi@gsi.de HupinGuillaumeGANIL, Caenhupin@ganil.fr JinMengHuazhong Normal University, Wuhanjinm@iopp.ccnu.edu.cn KamimuraMasayasuRIKEN Nishina Center, Wakomkamimura@riken.jp Kanada-En'yoYoshikoKyoto Universityyenyo@ruby.scphys.kyoto-u.ac.jp KatoKiyoshiHokkaido University, Sapporokato@nucl.sci.hokudai.ac.jp KawabataTakahiroKyoto Universitykawabata@scphys.kyoto-u.ac.jp KhanEliasIPN Orsaykhan@ipno.in2p3.fr

  5. PREFACE: Nanosafe2010: International Conference on Safe Production and Use of Nanomaterials

    NASA Astrophysics Data System (ADS)

    Sentein, Carole; Schuster, Frédéric; Tardif, François

    2011-07-01

    matters of interest to the NanoSafety community have been debated. The success of the conference confirms the need of such a global meeting with the aim of bridging the gap between the best scientists, engineers, exhibitors and participants from countries concerned with safe and responsible nanomaterial activities. Therefore, the third edition of the International NanoSafe Conference "NanoSafe2012" will be held in Grenoble at Minatec, 13-15 November 2012. The meeting was financially supported by generous contributions from the European Commission, La Région Rhône Alpes, la Ville de Grenoble, la Metro, and partners such as CEA, INERIS, Philips, Cordouan Technologies, Nanosight, TSI, Ecomesure, GRIMM Aerosol Technik, Particle Measuring Systems, Respirex, Lux Research, Dekati, Malvern Instruments, TSE Systems, INTERTEK ICS, NANO magazine and IOP Publishing. We would like to express our thanks to all the authors for their time and genuine efforts and to the reviewers for their fruitful comments during the preparation of this volume. The Conference OrganizersCarole SenteinFrédéric SchusterFrançois Tardif Conference photographs Local Organising CommitteeCarole SENTEIN (CEA)Dominique BAGUET (CEA)Didier MOLKO (MINATEC)Audrey SCARINGELLA (MINATEC)Frédéric SCHUSTER (CEA)François TARDIF (CEA) International Advisory CommitteeChair: Frédéric SCHUSTER (CEA, FR), François TARDIF (CEA, FR)Co-chair: Georgios KATALAGARIANAKIS (EC, BE)Paul AMYOTTE (Dalhousie U., CA)Mélanie AUFFAN (CEREGE, FR)Daniel BERNARD (ARKEMA, FR)Jorge BOCZKOWSKI (INSERM, FR)Jean-Yves BOTTERO (CEREGE, FR)Jacques BOUILLARD (INERIS, FR)Jean-Philippe BOURGOIN (CEA, FR)Marie CARRIERE (CEA, FR)Krunal CHOPRA (LSFI, IN)Rolf ECKHOFF (U. Bergen, NO)Michael ELLENBECKER (U. Massachusetts, USA)Claude EMOND (U. Montréal, CA)François GENDARMES (IRSN, FR)Peter HATTO (ISO, UK)Peter HOET (KUL, BE)Jean-Pierre KAISER (Empa, CH)Olivier LE BIHAN (INERIS, FR)Tinh NGUYEN (NIST, USA)Bernd NOWACK (Empa, CH)Günter OBERDÖRSTER (U

  6. PREFACE: Seventh International Conference on Dissociative Recombination: Theory, Experiments and Applications

    NASA Astrophysics Data System (ADS)

    van der Zande, Wim J.

    2009-09-01

    possible by generous sponsors, whom we thank wholeheartedly: The Radboud University Nijmegen, The Institute for Molecules and Materials of the Radboud University Nijmegen, The Foundation for Fundamental Research on Matter (Stichting FOM), The Foundation PHYSICA (Stichting Physica), and The Netherlands Royal Academy of Sciences (KNAW). The organisational support by Erna Gouwens van Oss before and during the conference was essential for its success. The help of Thanja Lambrechts and Vitali Zhaunerchyk during the preparation of the proceedings is greatly appreciated. The delay in the publication of these proceedings is entirely caused by the editor. The authors of the contributions are thanked for the quality of their contributions, Wim J van der Zande, Editor Institute for Molecules and Materials, Radboud University Nijmegen, PO Box 9010, NL-6500 GL Nijmegen, The Netherlands Email: w.vanderzande@science.ru.nl Conference photograph Participants of the 7th International Conference on Dissociative Recombination: Theory, Experiments and Applications, taken in front of d'Amelander Kaap, the conference venue in Ameland, one of the Wadden Islands in the North of the Netherlands. 1. Dror Shafir21. Annemieke Petrignani41. Oumanou Motopan 2. Ioan Scheider22. Johanna Roos42. Max Berg 3. Nigel Adams23. Erna Gouwens van Oss43. Henrik Buhr 4. Hajime Tanuma24. Natalie de Ruette44. Ilya Fabrikant 5. Jonathan Tennyson25. Francois Wameu Tamo45. Claude Krantz 6. Vitali Zhaunerchyk26. Rainer Johnsen46. Michael Stenrup 7. Robert Continetti27. Viatcheslav Kokoouline47. Xavier Urbain 8. Stefan Rosén28. Hidekazu Takagi48. Evelyne Roueff 9. Erik Vigren29. Hans-Jakob Wörner49. Dirk Schwalm 10. Magdalena Kaminska30. Oskar Asvany50. Valery Ngassam 11. Chris Greene31. Lutz Lammich51. Julien Lecointre 12. Steffen Novotny32. Brandon Jordon-Thaden52. Ann Orel 13. Amy Schumak33. Wolf Diettrich Geppert53. Ihor Korolov 14. Gerard van Rooij34. Alexander Faure54. Romain Guerot 15. Wim van der Zande35. Mathias

  7. Geological investigation for CO2 storage: from seismic and well data to storage design

    NASA Astrophysics Data System (ADS)

    Chapuis, Flavie; Bauer, Hugues; Grataloup, Sandrine; Leynet, Aurélien; Bourgine, Bernard; Castagnac, Claire; Fillacier, Simon; Lecomte, Antony; Le Gallo, Yann; Bonijoly, Didier

    2010-05-01

    Geological investigation for CO2 storage: from seismic and well data to storage design Chapuis F.1, Bauer H.1, Grataloup S.1, Leynet A.1, Bourgine B.1, Castagnac C.1, Fillacier, S.2, Lecomte A.2, Le Gallo Y.2, Bonijoly D.1. 1 BRGM, 3 av Claude Guillemin, 45060 Orléans Cedex, France, f.chapuis@brgm.fr, d.bonijoly@brgm.fr 2 Geogreen, 7, rue E. et A. Peugeot, 92563 Rueil-Malmaison Cedex, France, ylg@greogreen.fr The main purpose of this study is to evaluate the techno-economical potential of storing 200 000 tCO2 per year produced by a sugar beat distillery. To reach this goal, an accurate hydro-geological characterisation of a CO2 injection site is of primary importance because it will strongly influence the site selection, the storage design and the risk management. Geological investigation for CO2 storage is usually set in the center or deepest part of sedimentary basins. However, CO2 producers do not always match with the geological settings, and so other geological configurations have to be studied. This is the aim of this project, which is located near the South-West border of the Paris Basin, in the Orléans region. Special geometries such as onlaps and pinch out of formation against the basement are likely to be observed and so have to be taken into account. Two deep saline aquifers are potentially good candidates for CO2 storage. The Triassic continental deposits capped by the Upper Triassic/Lower Jurassic continental shales and the Dogger carbonate deposits capped by the Callovian and Oxfordian shales. First, a data review was undertaken, to provide the palaeogeographical settings and ideas about the facies, thicknesses and depth of the targeted formations. It was followed by a seismic interpretation. Three hundred kilometres of seismic lines were reprocessed and interpreted to characterize the geometry of the studied area. The main structure identified is the Étampes fault that affects all the formations. Apart from the vicinity of the fault where drag

  8. Second Chandra Instrument Activated August 28

    NASA Astrophysics Data System (ADS)

    1999-08-01

    Cambridge, MA--NASA's Chandra X-ray Observatory opened a new era in astronomy Saturday, August 28, by making the most precise measurements ever recorded of the energy output from the 10 million degree corona of a star. Last weekend's observations came after the successful activation of an instrument developed by MIT that will allow a one-thousand-fold improvement in the capability to measure X-ray spectra from space. The new measurements, made with the High Energy Transmission Grating Spectrometer, join spectacular images taken last week by Chandra of the aftermath of a gigantic stellar explosion. The spectrometer is one of four key instruments aboard Chandra, and the second to be activated. The others will be turned on over the next two weeks. The spectrometer activated yesterday spreads the X-rays from Chandra's mirrors into a spectrum, much as a prism spreads light into its colors. The spectrum then can be read by Chandra's imaging detectors like a kind of cosmic bar code from which scientists can deduce the chemical composition and temperature of the corona. A corona is a region of hot gas and magnetic loops that extend hundreds of thousands of miles above the star's visible surface and is best studied with X-rays. "The success of the new spectrometer is definitely a major milestone for modern astronomy," said MIT Professor Claude R. Canizares, principal investigator for the instrument and associate director of the Chandra X-ray Observatory Center (CXC). "Within the first hour we had obtained the best X-ray spectrum ever recorded for a celestial source. We can already see unexpected features that will teach us new things about stars and about matter at high temperatures." The spectrometer measured X-rays from the star Capella, which is 40 light years away in the constellation Auriga. Capella is actually two stars orbiting one another and possibly interacting in ways that pump extra heat into the corona, which appears more active than that of the Sun. How a star

  9. "Heart" of Herschel to be presented to media

    NASA Astrophysics Data System (ADS)

    2007-09-01

    instruments were designed and built by consortia of scientists and institutes, with their own national funding. The Photodetector Array Camera and Spectrometer (PACS) was developed under the coordination of the MPE, Germany; the Spectral and Photometric Imaging Receiver (SPIRE) was developed under the coordination of the Cardiff University (United Kingdom); the Heterodyne Instrument for the Far Infrared (HIFI) was developed under the coordination of the SRON institute (The Netherlands). For more information ESA Media Relations Office Tel: +33(0)1.53.69.7299 Fax: +33(0)1.53.69.7690 Herschel Press Day at Astrium, Friedrichshafen, Germany 19 September 2007 Claude-Dornier-Strasse 88090 Immenstaad 09:00 h Arrival at Astrium /Check-in / Transfer to Building 8 / Room Meersburg (5 th floor) 09:30 h Welcome, by Uwe Minne, Director of Earth Observation and Science, Astrium 09:35 h ESA and Astronomy: looking forward, by Jacques Louet, Head of Scientific Projects Department, ESA 09:45 h Herschel/Planck mission overview, by Thomas Passvogel, ESA Herschel/Planck Project Manager 09:55 h The Herschel scientific mission, by Göran Pilbratt, ESA Herschel Project Scientist 10:05 h Q & A followed by coffee break 10:30 h Herschel spacecraft overview, by Jean-Jacques Julliet, Director of European Science and Optical Observation Programmes, Thales Alenia Space 10:40 h The ‘cool’ heart of Herschel, by Wolfgang Fricke, Herschel Project Manager, Astrium 10:50 h The PACS instrument, by Albrecht Poglitsch, Principal Investigator, Max-Planck-Institut für extraterrestrische Physik (MPE) 11:00 h The SPIRE instrument, by Matthew Griffin, Principal Investigator, Cardiff University 11:10 h The HIFI instrument, by Thijs de Graauw, Principal Investigator, Netherlands Institute for Space Research (SRON) 11:20 h Q & A, Individual Interviews 12:15 h Transfer to Integration Centre 12:30 h Warm / Cold Buffet on Visitoŕs Galaxy Build up of three different visitor groups Check-in into cleanroom Photo

  10. Original sounding and drifting balloon-borne measurements in the western Mediterranean with the aerosol counter/sizer LOAC during summer ChArMEx campaigns, with a focus on desert dust events

    NASA Astrophysics Data System (ADS)

    Renard, Jean-Baptiste; Dulac, François; Vignelles, Damien; Jeannot, Matthieu; Verdier, Nicolas; Chazette, Patrick; Crenn, Vincent; Sciare, Jean; Totems, Julien; Durand, Pierre; Barret, Brice; Jambert, Corinne; Mallet, Marc; Menut, Laurent; Mailler, Sylvain; Basart, Sara; Baldasano, José Maria

    2015-04-01

    ) in late July and early August . A number of the 2013 flights were coupled with ozone concentration measurements (see presentation of Gheusi et al. in the same session). LOAC balloons were especially, but not only, dedicated to study the various Saharan dust events that occurred during the campaign. In particular, a series of flights were conducted every 12 hours during the 15-19 June dust event. Forest fire smoke from North America was also sampled in late June over Minorca, as well as anthropogenic polluted layers in various occasions. LOAC data (available from ChArMEx database http://mistrals.sedoo.fr/ChArMEx) are interpreted with the help of coincident lidar, sun photometer remote sensing measurements available in Menorca, and satellite products and air mass trajectories. The sounding flights allow us to determine the vertical extent of the various aerosol layers, and to follow the particle size distribution and the concentration evolution along the vertical. The low altitude drifting balloons, which stayed roughly at constant altitude between 350 and 3330 m up to more than 25 h, allow us to study the time-evolution of the aerosol concentrations in the same air mass. Under both balloon types, LOAC has detected larges particles up to ~30 µm in diameter. The flights drifting within dust layers indicate that there is a relatively stable particle size distribution during transport over the sea, with no clear sedimentation loss of large particles. Aerosol simulations with the CHIMERE and NMMB/§BSC chemistry-transport models are compared to LOAC measurements. Acknowledgements: LOAC was developed with support of the French ANR. Balloon operations were performed by CNES and special acknowledgements are addressed to Gilles Dupouy, Françoise Douchin and collaborators for field operations. Alexis Doerenbacher from Météo-France and Claude Basdevant from Ecole Polytechnique are also acknowledged for their helpful contribution in providing balloon-related forecasts

  11. Chandra Finds Oxygen and Neon Ring in Ashes of Exploded Star

    NASA Astrophysics Data System (ADS)

    2000-01-01

    NASA's Chandra X-ray Observatory has revealed an expanding ring-like structure of oxygen and neon that was hurled into space by the explosion of a massive star. The image of E0102-72 provides unprecedented details about the creation and dispersal of heavy elements necessary to form planets like Earth. The results were reported by Professor Claude Canizares of the Massachusetts Institute of Technology (MIT), Cambridge, at the 195th national meeting of the American Astronomical Society in Atlanta, Ga. Drs. Kathryn Flanagan, David Davis, and John Houck of MIT collaborated with Canizares in this investigation. E0102-72 is the remnant of a supernova explosion located in our neighbor galaxy, the Small Magellanic Cloud, nearly 200,000 light years away. It was created by the explosion of a star that was more than ten times as massive as our Sun. We are seeing the aftermath of the explosion a thousand or more years after the outburst. Shock waves are heating gas to temperatures of nearly 10 million degrees, so it glows with X-rays that are detected by Chandra's instruments. By using the High Energy Transmission Grating Spectrometer (HETG), astronomers were able to pinpoint the distribution of each chemical element individually and measure the velocities of different parts of the expanding ring. They also show the shock wave in a kind of "freeze-frame," revealing the progressive heating of the stellar matter as it plows into the surrounding gas. This is the first time such detailed X-ray information has ever been obtained for a supernova remnant, and should provide critical clues to the nature of supernovas. The grating spectrometer, which was built by an MIT team led by Canizares, spreads the X-rays according to their wavelength, giving distinct images of the object at specific wavelengths characteristic of each chemical element. Small wavelength shifts caused by the Doppler effect are used to measure the expansion velocities of each element independently. "We've been

  12. Second Chandra Instrument Activated August 28

    NASA Astrophysics Data System (ADS)

    1999-08-01

    Cambridge, MA--NASA's Chandra X-ray Observatory opened a new era in astronomy Saturday, August 28, by making the most precise measurements ever recorded of the energy output from the 10 million degree corona of a star. Last weekend's observations came after the successful activation of an instrument developed by MIT that will allow a one-thousand-fold improvement in the capability to measure X-ray spectra from space. The new measurements, made with the High Energy Transmission Grating Spectrometer, join spectacular images taken last week by Chandra of the aftermath of a gigantic stellar explosion. The spectrometer is one of four key instruments aboard Chandra, and the second to be activated. The others will be turned on over the next two weeks. The spectrometer activated yesterday spreads the X-rays from Chandra's mirrors into a spectrum, much as a prism spreads light into its colors. The spectrum then can be read by Chandra's imaging detectors like a kind of cosmic bar code from which scientists can deduce the chemical composition and temperature of the corona. A corona is a region of hot gas and magnetic loops that extend hundreds of thousands of miles above the star's visible surface and is best studied with X-rays. "The success of the new spectrometer is definitely a major milestone for modern astronomy," said MIT Professor Claude R. Canizares, principal investigator for the instrument and associate director of the Chandra X-ray Observatory Center (CXC). "Within the first hour we had obtained the best X-ray spectrum ever recorded for a celestial source. We can already see unexpected features that will teach us new things about stars and about matter at high temperatures." The spectrometer measured X-rays from the star Capella, which is 40 light years away in the constellation Auriga. Capella is actually two stars orbiting one another and possibly interacting in ways that pump extra heat into the corona, which appears more active than that of the Sun. How a star

  13. XMM telescope goes on show for the first time

    NASA Astrophysics Data System (ADS)

    1997-05-01

    formed in an electrochemical bath. As each finished mirror was only about a millimetre thick, the Medio Lario team had to handle it with great care to avoid flexing, until it was glued into position among all the other mirrors, between wheel-like "spiders" fabricated by APCO in Switzerland. If the telescope is correctly made, all X-rays coming from a certain direction, and entering any part of any of the mirrors, should go to the same focus. The specification requires that any spread at the focus should be less than a millimetre. The optical quality is tested first in a special apparatus at LiŠge called FOCAL X, and then at the Panter X-ray facility at Neuried in Germany. "We take pride and satisfaction in helping to develop such remarkable telescopes," says Claude Jamar, director of CSL. "While others pioneered the methods of fabrication, here in LiŠge we had to invent novel ways of checking the performance. We use a wide beam of very short ultraviolet wavelengths to simulate X-rays, and verify the focus of each part of each XMM telescope." About the Centre Spatial de Liège As a laboratory unique in western Europe, CSL is run by the Université de Liège as one of ESA's coordinated test facilities.Optical instruments for space missions can be checked with high accuracy, under a high vacuum that simulates the airless conditions in space. ESA relies upon CSL for testing important optical components for many spacecraft. The long list includes the radiometer of the Meteosat weather satellite, the camera for Giotto which obtained unique pictures of Halley's Comet, and the telescopes of the Hipparcos star-fixing mission and the Infrared Space Observatory ISO. CSL was an early recruit to the Europe-wide teams of scientists and engineers who are creating the XMM spacecraft and its instruments. Other optical devices currently under evaluation by CSL include the experimental laser system SILEX for communication between satellites, and the ozone-monitoring GOMOS instrument for

  14. 1992 WAMET/EUROMET Joint Expedition to Search for Meteorites in the Nullarbor Region, Western Australia

    NASA Astrophysics Data System (ADS)

    Bevan, A.

    1992-07-01

    The Nullarbor Region is a limestone desert in the south of Australia. It forms part of the larger Eucla Basin, which straddles the border between South Australia and Western Australia. The portion of the Eucla Basin lying in Westem Australia covers an area of about 104,000 km^2 (Bevan and Binns, 1989) and meteorites have been recovered from this region since 1971, new material being deposited at the Western Australia Museum. Between 21/3/92 and 6/4/92 a joint expedition between the Western Australia Museum and EUROMET recovered approximately 440 specimens of meteorites (total mass 13206 g) and 297 tektites. The expedition, whose members were Claude Perron (Paris), Christian Koeberl (Vienna), Georg Delisle (BGR Hannover), Gian- Paolo Sighinolfi (Modena), and Andrew Morse (OU) for Euromet, together with Wayne Smith (Australian Army) and Tom Smith (Perth Astronomical Observatory), was led by Dr Alex Bevan of the Western Australia Museum. Searching was carried out on foot with the participants spread out in a line with a 10-m spacing, walking along a compass bearing for approximately 10 km and back each day. Eight collecting regions were used, with a stop of about 2 days at each camp. Half of the searching was done near known strewn fields in order that the team become practised. Thus the expedition collected material at the following known sites. Camel Donga, Eucrite: The initial recovery was made in 1984 (Cleverly et al., 1986). The strewn field is about 8 km by 2-3 km at coordinates 30 degrees 19'S, 126 degrees 37'E. This expedition recovered 65 stones weighing a total of 2456 g, plus one stone of 4.8 g that was clearly chondritic in hand specimen. Mulga (north), H6: The initial recovery was made in 1964 (McCall, 1968). The strewn field is 8 km by 2 km at coordinates 30 degrees 11'S, 126 degrees 22'E and on this expedition 5 stones were recovered with a weight of 548 g. Also 110 stones (total mass 1535 g) that are certainly not H6 were found within a 100-m radius of

  15. The Project Serapis: High Resolution Seismic Imagingof The Campi Flegrei Caldera Structure

    NASA Astrophysics Data System (ADS)

    Zollo, A.; Virieux, J.; Capuano, P.; Chiarabba, C.; de Franco, R.; Makris, J.; Michelini, A.; Musacchio, G.; Serapis Group

    , Iannaccone Giovanni, La Rocca Mario, Saccorotti Gilberto, Cattaneo Marco, De Mar- tin Martina , Colasanti Gianfranco, Moretti Milena, Marcello Silvestri, Edoardo Gian- domenico, Raffaele Stefano, Graziano Boniolo, Maria Rosaria Tondi, Maistrello Mar- iano, Gomez Antonio, Piccareda Carlo, Paolo Di Bartolomeo, Marco Romanelli, So- phie Peyrat, Christophe Larroque, Claude Pambrun, Tony Monfret, Stephane Gaffet, Mark Noble, Sylvain Nguyen 2

  16. Original sounding and drifting balloon-borne measurements in the western Mediterranean with the aerosol counter/sizer LOAC during summer ChArMEx campaigns, with a focus on desert dust events

    NASA Astrophysics Data System (ADS)

    Renard, Jean-Baptiste; Dulac, François; Vignelles, Damien; Jeannot, Matthieu; Verdier, Nicolas; Chazette, Patrick; Crenn, Vincent; Sciare, Jean; Totems, Julien; Durand, Pierre; Barret, Brice; Jambert, Corinne; Mallet, Marc; Menut, Laurent; Mailler, Sylvain; Basart, Sara; Baldasano, José Maria

    2015-04-01

    ) in late July and early August . A number of the 2013 flights were coupled with ozone concentration measurements (see presentation of Gheusi et al. in the same session). LOAC balloons were especially, but not only, dedicated to study the various Saharan dust events that occurred during the campaign. In particular, a series of flights were conducted every 12 hours during the 15-19 June dust event. Forest fire smoke from North America was also sampled in late June over Minorca, as well as anthropogenic polluted layers in various occasions. LOAC data (available from ChArMEx database http://mistrals.sedoo.fr/ChArMEx) are interpreted with the help of coincident lidar, sun photometer remote sensing measurements available in Menorca, and satellite products and air mass trajectories. The sounding flights allow us to determine the vertical extent of the various aerosol layers, and to follow the particle size distribution and the concentration evolution along the vertical. The low altitude drifting balloons, which stayed roughly at constant altitude between 350 and 3330 m up to more than 25 h, allow us to study the time-evolution of the aerosol concentrations in the same air mass. Under both balloon types, LOAC has detected larges particles up to ~30 µm in diameter. The flights drifting within dust layers indicate that there is a relatively stable particle size distribution during transport over the sea, with no clear sedimentation loss of large particles. Aerosol simulations with the CHIMERE and NMMB/§BSC chemistry-transport models are compared to LOAC measurements. Acknowledgements: LOAC was developed with support of the French ANR. Balloon operations were performed by CNES and special acknowledgements are addressed to Gilles Dupouy, Françoise Douchin and collaborators for field operations. Alexis Doerenbacher from Météo-France and Claude Basdevant from Ecole Polytechnique are also acknowledged for their helpful contribution in providing balloon-related forecasts

  17. List of Posters

    NASA Astrophysics Data System (ADS)

    . Saturation effects in diffractive scattering at LHC By Oleg Selugin. A nonperturbative expansion method in QCD and R-related quantities By Igor Solovtsov. Z-scaling and high multiplicity particle Production in bar pp/pp & AA collisions at Tevatron and RHIC By Mikhail Tokarev. Scaling behaviour of the reactionsdd - > p↑ /3H and pd - > pd with pT at energy I-2 GeV By Yuri Uzikov. [ADS Note: Title formula can not be rendered correctly in ASCII.] CP violation, rare decays, CKM: Precision Measurements of the Mass of the Top Quark at CDF (Precision Top Mass Measurements at CDF) By Daniel Whiteson. Measurement of the Bs Oscillation at CDF By Luciano Ristori. The Bs mixing phase at LHCb By J. J. van Hunen. ATLAS preparations for precise measurements of semileptonic rare B decays By K. Toms. Hadron spectroscopy & exotics: Searches for radial excited states of charmonium in experiments using cooled antiproton beams By M. Yu. Barabanov. Retardation effects in the rotating string model By Fabien Buisseret and Claude Semay. Final results from VEPP-2M (CMD-2 and SND) By G. V. Fedotovich. Heavy Quark Physics: Prospects for B physics measurements using the CMS detector at the LHC By Andreev Valery. Heavy flavour production at HERA-B By Andrey Bogatyrev. B-Meson subleading form factors in the Heavy Quark Effective Theory (HQET) By Frederic Jugeau. Beyond the Standard Model: Monopole Decay in a Variable External Field By Andrey Zayakin. Two-Loop matching coefficients for the strong coupling in the MSSM By Mihaila Luminita. Test of lepton flavour violation at LHC By Hidaka Keisho. Looking at New Physics through 4 jets and no ET By Maity Manas. Are Preons Dyons? Naturalness of Three Generations By Das Chitta Ranjan. SUSY Dark Matter at Linear Collider By Sezen Sekmen, Mehmet Zeyrek. MSSM light Higgs boson scenario and its test at hadron colliders By Alexander Belyaev. Antiscalar Approach to Gravity and Standard Model By E. Mychelkin. GRID distributed analysis in high energy physics: PAX

  18. HUBBLE PROVIDES COMPLETE VIEW OF JUPITER'S AURORAS

    NASA Technical Reports Server (NTRS)

    2002-01-01

    's Goddard Space Flight Center) Jean-Claude Gerard (University of Liege, Belgium) Randy Gladstone and Hunter Waite (Southwest Research Institute) Wayne Pryor (University of Colorado) Daniel Rego (University College, London)

  19. PREFACE: Ocean and climate changes in polar and sub-polar environments: proceedings from the 2010 IODP-Canada/ECORD summer school

    NASA Astrophysics Data System (ADS)

    St-Onge, Guillaume; Veiga-Pires, Cristina; Solignac, Sandrine

    2011-05-01

    /GEOTOP, Canada) Mathieu Duchesne (Geological Survey of Canada-Québec, Canada) Frédérique Eynaud (EPOC/Universite Bordeaux I, France) Pierre Francus (INRS-ETE/GEOTOP, Canada) Martin Frank (IFM-GEOMAR, Germany) Yves Gélinas (Concordia/GEOTOP, Canada) Joël Guiot (CEREGE, France) Claude Hillaire-Marcel (UQAM/GEOTOP, Canada) Patrick Lajeunesse (University Laval, Canada) Jean-François Lemieux (Courant Institute of Mathematical Sciences, New York University, USA) Guillaume Massé (LOCEAN/Institut Pierre-Simon Laplace, France) Matt O'Regan (Cardiff University, UK) Joseph Ortiz (Kent State University, USA) Frank Rack (University Nebraska-Lincoln, USA/ANDRILL Science Management Office) Taoufik Radi (UQAM/GEOTOP, Canada) André Rochon (ISMER-UQAR/GEOTOP, Canada) Ruediger Stein (Alfred Wegener Institute, Germany) Guillaume St-Onge (ISMER-UQAR/GEOTOP, Canada) Bjorn Sundby (ISMER-UQAR, Canada) GEOTOP logoUQAM UQAR logoINRS logo Universite de Quebec logoGeological Survey of Canada logo

  20. PREFACE: International Conference on the Applications of the Mössbauer Effect (ICAME 2009)

    NASA Astrophysics Data System (ADS)

    Müller, Herbert; Reissner, Michael; Steiner, Walter; Wiesinger, Günter

    2010-04-01

    . The positive atmosphere, the high attendance in the sessions and the lively discussions made the conference a great success and a memorable event. It was pointed out, that Mössbauer spectroscopy is still an interesting and powerful method with great opportunities in the future. Herbert Müller (Secretary) Michael Reissner (Chairman) This book is dedicated to our colleagues Nicol Malcom, who could not come, because he suddenly died a few weeks in advance to the conference and Hercilio Rechenberg, who died on his way home from Vienna. Conference photograph Conference Organisation Local Organizing Committee Reissner Michael (Chairman)Müller Herbert (Conference Secretary) Amthauer Georg Lottermoser WernerSteiner Walter Bauer Ernst Michor Herwig Vogl Gero Bühler-Paschen Silke Müller Martin Waas Monika Grodzicki Michael Redhammer Günther Wiesinger Günter Grössinger Roland Sassik Herbert Hilscher Gerfried Sepiol Bogdan International Programme Committee Amthauer Georg Gütlich Philipp Steiner Walter Baggio-Saitovich Elisa Litterst Fred Jochen Trautwein Alfred Xaver Berry Frank Long Gary Vogl Gero Felner Israel Nagy Denes Lajos Yoshida Yutaka Greneche Jean-Marc Rüffer Rudolf International Advisory Board Alp E ErcanGénin Jean-Marie Baggio-Saitovitch Elisa Greneche Jean-Marc Miglierini Marcel Balogh Judit Grodzicki Michael Musić Svetozar Bender Koch Christian Gütlich Philipp Nagy Dénes Lajos Berry Frank Häggström Lennart Nishida Tetsuaki Brown Dennis Hanzel Darko Pérez Alcázar German Campbell Stewart Hassaan Mohamed Yousri Rüffer Rudolf Carbucicchio Massimo Jumas Jean-Claude Ryan Dominic H Croci Simonetta Kadyrzhanov Kariat Sanchez Francisco Di Naili Katila Toivo Schünemann Volker Elzain Mohamed Kim Chul Sung Stanek Jan Fabris José Domingos Klingelhöfer Göstar Stevens John Felner Israel Langouche Guido Suzdalev Igor P Fern George R Lyubutin Igor S Szymanski Krzysztof Forder Sue D Marco Jose F Waanders Frans Gajbhiye Nandeo Mašlaň Miroslav Yoshida Yutaka