21 CFR 610.18 - Cultures.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Cultures. 610.18 Section 610.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS GENERAL... biological products shall be: (i) Identified by history; (ii) Described with respect to cytogenetic...

21 CFR 610.18 - Cultures.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Cultures. 610.18 Section 610.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS GENERAL... biological products shall be: (i) Identified by history; (ii) Described with respect to cytogenetic...

21 CFR 610.18 - Cultures.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Cultures. 610.18 Section 610.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS GENERAL... biological products shall be: (i) Identified by history; (ii) Described with respect to cytogenetic...

21 CFR 610.18 - Cultures.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Cultures. 610.18 Section 610.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS GENERAL... contamination and deterioration. (b) Identity and verification. Each culture shall be clearly identified as to...

18 CFR 5.21 - Additional information.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Additional information. 5.21 Section 5.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE APPLICATION PROCESS § 5.21...

18 CFR 5.21 - Additional information.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Additional information. 5.21 Section 5.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT INTEGRATED LICENSE APPLICATION PROCESS § 5.21...

21 CFR 26.18 - Regulatory collaboration.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Regulatory collaboration. 26.18 Section 26.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL MUTUAL... Specific Sector Provisions for Pharmaceutical Good Manufacturing Practices § 26.18 Regulatory collaboration...

18 CFR 1301.21 - Fees.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Fees. 1301.21 Section... § 1301.21 Fees. (a) Fees to be charged, if any, to any individual for making copies of his or her record exclude the cost of any search and review of the record. The following fees are applicable: (1) For...

27 CFR 21.43 - Formula No. 18.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Formula No. 18. 21.43... OF THE TREASURY LIQUORS FORMULAS FOR DENATURED ALCOHOL AND RUM Specially Denatured Spirits Formulas and Authorized Uses § 21.43 Formula No. 18. (a) Formula. To every 100 gallons of alcohol of not less...

27 CFR 21.43 - Formula No. 18.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Formula No. 18. 21.43... OF THE TREASURY LIQUORS FORMULAS FOR DENATURED ALCOHOL AND RUM Specially Denatured Spirits Formulas and Authorized Uses § 21.43 Formula No. 18. (a) Formula. To every 100 gallons of alcohol of not less...

27 CFR 21.43 - Formula No. 18.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Formula No. 18. 21.43... OF THE TREASURY ALCOHOL FORMULAS FOR DENATURED ALCOHOL AND RUM Specially Denatured Spirits Formulas and Authorized Uses § 21.43 Formula No. 18. (a) Formula. To every 100 gallons of alcohol of not less...

27 CFR 21.43 - Formula No. 18.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Formula No. 18. 21.43... OF THE TREASURY ALCOHOL FORMULAS FOR DENATURED ALCOHOL AND RUM Specially Denatured Spirits Formulas and Authorized Uses § 21.43 Formula No. 18. (a) Formula. To every 100 gallons of alcohol of not less...

21 CFR 1301.18 - Research protocols.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Research protocols. 1301.18 Section 1301.18 Food..., DISTRIBUTORS, AND DISPENSERS OF CONTROLLED SUBSTANCES Registration § 1301.18 Research protocols. (a) A protocol to conduct research with controlled substances listed in Schedule I shall be in the following form...

21 CFR 1301.18 - Research protocols.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Research protocols. 1301.18 Section 1301.18 Food..., DISTRIBUTORS, AND DISPENSERS OF CONTROLLED SUBSTANCES Registration § 1301.18 Research protocols. (a) A protocol to conduct research with controlled substances listed in Schedule I shall be in the following form...

21 CFR 1301.18 - Research protocols.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Research protocols. 1301.18 Section 1301.18 Food..., DISTRIBUTORS, AND DISPENSERS OF CONTROLLED SUBSTANCES Registration § 1301.18 Research protocols. (a) A protocol to conduct research with controlled substances listed in Schedule I shall be in the following form...

21 CFR 1301.18 - Research protocols.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Research protocols. 1301.18 Section 1301.18 Food..., DISTRIBUTORS, AND DISPENSERS OF CONTROLLED SUBSTANCES Registration § 1301.18 Research protocols. (a) A protocol to conduct research with controlled substances listed in Schedule I shall be in the following form...

21 CFR 1301.18 - Research protocols.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Research protocols. 1301.18 Section 1301.18 Food..., DISTRIBUTORS, AND DISPENSERS OF CONTROLLED SUBSTANCES Registration § 1301.18 Research protocols. (a) A protocol to conduct research with controlled substances listed in Schedule I shall be in the following form...

New constraints shed light on strike-slip faulting beneath the southern Apennines (Italy): The 21 August 1962 Irpinia multiple earthquake

NASA Astrophysics Data System (ADS)

Vannoli, Paola; Bernardi, Fabrizio; Palombo, Barbara; Vannucci, Gianfranco; Console, Rodolfo; Ferrari, Graziano

2016-11-01

On 21 August 1962 an earthquake sequence set off near the city of Benevento, in Italy's southern Apennines. Three earthquakes, the largest having Mw 6.1, struck virtually the same area in less than 40 min (at 18:09, 18:19 and 18:44 UTC, respectively). Several historical earthquakes hit this region, and its seismic hazard is accordingly among the highest countrywide. Although poorly understood in the past, the seismotectonics of this region can be revealed by the 1962 sequence, being the only significant earthquake in the area for which modern seismograms are available. We determine location, magnitude, and nodal planes of the first event (18:09 UTC) of the sequence. The focal mechanism exhibits dominant strike-slip rupture along a north-dipping, E-W striking plane or along a west-dipping, N-S striking plane. Either of these solutions is significantly different from the kinematics of the typical large earthquakes occurring along the crest of the Southern Apennines, such as the 23 November 1980 Irpinia earthquake (Mw 6.9), caused by predominant normal faulting along NW-SE-striking planes. The epicentre of the 21 August 1962, 18:09 event is located immediately east of the chain axis, near one of the three north-dipping, E-W striking oblique-slip sources thought to have caused one of the three main events of the December 1456 sequence (Io XI MCS), the most destructive events in the southern Apennines known to date. We maintain that the 21 August 1962, 18:09 earthquake occurred along the E-W striking fault system responsible for the southernmost event of the 1456 sequence and for two smaller but instrumentally documented events that occurred on 6 May 1971 (Mw 5.0) and 27 September 2012 (Mw 4.6), further suggesting that normal faulting is not the dominant tectonic style in this portion of the Italian peninsula.

The new Zintl phases Eu{sub 21}Cd{sub 4}Sb{sub 18} and Eu{sub 21}Mn{sub 4}Sb{sub 18}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Yi; Darone, Gregory M.; Bobev, Svilen, E-mail: bobev@udel.edu

Crystals of two new Zintl compounds, Eu{sub 21}Mn{sub 4}Sb{sub 18} and Eu{sub 21}Cd{sub 4}Sb{sub 18} have been synthesized using the molten metal flux method, and their structures have been established by single-crystal X-ray diffraction. Both compounds are isotypic and crystallize in the monoclinic space group C2/m (No. 12, Z=4). The structures are based on edge- and corner-shared MnSb{sub 4} or CdSb{sub 4} tetrahedra, which make octameric [Mn{sub 8}Sb{sub 22}] or [Cd{sub 8}Sb{sub 22}] polyanions. Homoatomic Sb–Sb bonds are present in both structures. The Eu atoms take the role of Eu{sup 2+}cations with seven unpaired 4f electrons, as suggested by themore » temperature-dependent magnetization measurements. The magnetic susceptibilities of Eu{sub 21}Mn{sub 4}Sb{sub 18} and Eu{sub 21}Cd{sub 4}Sb{sub 18} indicate that both phases order anti-ferromagnetically with Néel temperatures of ca. 7 K and ca. 10 K, respectively. The unpaired 3d electrons of the Mn atoms in Eu{sub 21}Mn{sub 4}Sb{sub 18} do contribute to the magnetic response, however, the bulk magnetization measurements do not provide evidence for long-range ordering of the Mn spins down to 5 K. Electrical resistivity measurements suggest that both compounds are narrow band gap semiconductors. - Graphical abstract: Eu{sub 21}Mn{sub 4}Sb{sub 18} and Eu{sub 21}Cd{sub 4}Sb{sub 18} have complex monoclinic structures, based on MnSb{sub 4} and CdSb{sub 4} tetrahedra, both edge- and corner-shared. A perspective of the crystal structure is shown, as viewed along the b axis. Display Omitted - Highlights: • Eu{sub 21}Mn{sub 4}Sb{sub 18} and Eu{sub 21}Cd{sub 4}Sb{sub 18} are novel compounds in the respective ternary phase diagrams. • For both structures, the Zintl-Klemm rules are followed, and both are small gap semiconductors. • Eu{sub 21}Mn{sub 4}Sb{sub 18} and Eu{sub 21}Cd{sub 4}Sb{sub 18} are air-stable Zintl phases and could be new thermoelectric materials.« less

A rare case of monosomy 18p: translocation between chromosomes 18 and 21.

PubMed

Tos, T; Karaman, A; Aycan, Z; Tükün, A

2011-01-01

A rare case of monosomy 18p with molecular cytogenetic characterization of 18;21 whole arm translocation is presented. An 8-year-old gril with mental deficiency and growth deficiency was the child of a 45-year-old healthy mother and 50-year-old nonconsanguineous father with unremarkable prenatal history. She had a round face, flat nasal bridge, micrognathia and hypotonia. Cytogenetic studies revealed de novo 45,XX,del(18)t(18;21) karyotype, which was confirmed by fluorescence in situ hybridization (FISH).

21 CFR 26.18 - Regulatory collaboration.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Regulatory collaboration. 26.18 Section 26.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL MUTUAL RECOGNITION OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS...

18 CFR 415.21 - Class II projects.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Class II projects. 415.21 Section 415.21 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL BASIN REGULATIONS-FLOOD PLAIN REGULATIONS Types of Projects and Jurisdiction § 415.21 Class...

Late Glacial to Holocene environmental variabilities: A new multi-proxy paleolimnological study of sedimentary sequences from Como (northern Italy)

NASA Astrophysics Data System (ADS)

Höbig, N.; Martinelli, E.; Motella, S.; Michetti, A. M.; Livio, F.; Tinner, W.; Reicherter, K.; Castelletti, L.

2012-04-01

Lake Como (northern Italy) is the deepest Italian lake, reaching a depth of about 425 m. The lambda-shaped lake expands about 45 km in NE-SW direction. Southwards of the hydrologically closed western branch, two sediment cores of 70 m (S1) and 65 m length (S2) were taken in the year 2005 close to the cathedral of Como (Piazza Verdi). The drilling sites are located in the middle of the Southern Alps, some 300 m from the present-day lakeshore. The cores provide the first detailed Late Glacial to Holocene multi-proxy record for the Lake Como basin. Our research is aimed at investigating the environmental and geological evolution of the Insubria Region. The multi-proxy study of the stratigraphic sequences contain geophysical, geotechnical, sedimentological, paleobotanical, and radiocarbon analyses. They have been performed for core S1 and are still in progress on core S2. With this data the working group focuses on two main issues. The first topic is the reconstruction of the natural and anthropogenic processes controlling the ground subsidence in the Como urban area (e.g., Comerci et al., 2007) and another aim is to reconstruct vegetation and land-use dynamics. In particular, 150 samples of vegetal macroremains have been collected in the palustrine deposits along S1 core, down to 31,00 m. Below this depth (dated 14C 12,496 ± 55 yr BP - 15,050 - 14,250 cal yr BP), the amount of plant macroremains in the sediment drops dramatically. The taxonomic determination was carried out on more than 800 macroremains. They are represented by fragments of wood, leaves, needles, seeds, fruits, mosses and tiny charcoals (Motella, 2009, unpublished PhD Thesis). Picea/Larix, Pinus sp., Juniperus with Betula, found in the deeper levels (30.80 - 30.00 m), are the first arboreal taxa that colonized the shores of Lake Como, and show that the reforestation began in this area about 16,000 years ago. During the early Holocene (25.10 m) Abies alba expanded and further upwards the sequence

18 CFR 1b.21 - Enforcement hotline.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Enforcement hotline. 1b.21 Section 1b.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.21 Enforcement hotline. (a) The...

18 CFR 1b.21 - Enforcement hotline.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Enforcement hotline. 1b.21 Section 1b.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.21 Enforcement hotline. (a) The...

18 CFR 1b.21 - Enforcement hotline.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Enforcement hotline. 1b.21 Section 1b.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.21 Enforcement hotline. (a) The...

18 CFR 1b.21 - Enforcement hotline.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Enforcement hotline. 1b.21 Section 1b.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.21 Enforcement hotline. (a) The...

21 CFR 101.18 - Misbranding of food.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Misbranding of food. 101.18 Section 101.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FOOD LABELING General Provisions § 101.18 Misbranding of food. (a) Among...

21 CFR 101.18 - Misbranding of food.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Misbranding of food. 101.18 Section 101.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FOOD LABELING General Provisions § 101.18 Misbranding of food. (a) Among...

21 CFR 101.18 - Misbranding of food.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Misbranding of food. 101.18 Section 101.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FOOD LABELING General Provisions § 101.18 Misbranding of food. (a) Among...

21 CFR 101.18 - Misbranding of food.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Misbranding of food. 101.18 Section 101.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FOOD LABELING General Provisions § 101.18 Misbranding of food. (a) Among...

21 CFR 101.18 - Misbranding of food.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Misbranding of food. 101.18 Section 101.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FOOD LABELING General Provisions § 101.18 Misbranding of food. (a) Among...

21 CFR 341.18 - Expectorant active ingredient.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Expectorant active ingredient. 341.18 Section 341.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...-COUNTER HUMAN USE Active Ingredients § 341.18 Expectorant active ingredient. The active ingredient of the...

21 CFR 341.18 - Expectorant active ingredient.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Expectorant active ingredient. 341.18 Section 341.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...-COUNTER HUMAN USE Active Ingredients § 341.18 Expectorant active ingredient. The active ingredient of the...

21 CFR 341.18 - Expectorant active ingredient.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Expectorant active ingredient. 341.18 Section 341.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...-COUNTER HUMAN USE Active Ingredients § 341.18 Expectorant active ingredient. The active ingredient of the...

21 CFR 341.18 - Expectorant active ingredient.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Expectorant active ingredient. 341.18 Section 341.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...-COUNTER HUMAN USE Active Ingredients § 341.18 Expectorant active ingredient. The active ingredient of the...

18 CFR 2.21 - Regional Transmission Groups.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Regional Transmission Groups. 2.21 Section 2.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

18 CFR 2.21 - Regional Transmission Groups.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Regional Transmission Groups. 2.21 Section 2.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

18 CFR 2.21 - Regional Transmission Groups.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Regional Transmission Groups. 2.21 Section 2.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

18 CFR 2.21 - Regional Transmission Groups.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Regional Transmission Groups. 2.21 Section 2.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

27 CFR 21.43 - Formula No. 18.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Formula No. 18. 21.43 Section 21.43 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS FORMULAS FOR DENATURED ALCOHOL AND RUM Specially Denatured Spirits Formulas...

18 CFR 4.21 - Reports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Reports. 4.21 Section 4... Reports. Representatives of the Commission will inspect the project works, engineering reports, and other..., records, and accounts of the licensee relating to the property under license, and prepare a report of...

18 CFR 4.21 - Reports.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Reports. 4.21 Section 4... Reports. Representatives of the Commission will inspect the project works, engineering reports, and other..., records, and accounts of the licensee relating to the property under license, and prepare a report of...

18 CFR 4.21 - Reports.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Reports. 4.21 Section 4... Reports. Representatives of the Commission will inspect the project works, engineering reports, and other..., records, and accounts of the licensee relating to the property under license, and prepare a report of...

AMP-18 Targets p21 to Maintain Epithelial Homeostasis.

PubMed

Chen, Peili; Li, Yan Chun; Toback, F Gary

2015-01-01

Dysregulated homeostasis of epithelial cells resulting in disruption of mucosal barrier function is an important pathogenic mechanism in inflammatory bowel diseases (IBD). We have characterized a novel gastric protein, Antrum Mucosal Protein (AMP)-18, that has pleiotropic properties; it is mitogenic, anti-apoptotic and can stimulate formation of tight junctions. A 21-mer synthetic peptide derived from AMP-18 exhibits the same biological functions as the full-length protein and is an effective therapeutic agent in mouse models of IBD. In this study we set out to characterize therapeutic mechanisms and identify molecular targets by which AMP-18 maintains and restores disrupted epithelial homeostasis in cultured intestinal epithelial cells and a mouse model of IBD. Tumor necrosis factor (TNF)-α, a pro-inflammatory cytokine known to mediate gastrointestinal (GI) mucosal injury in IBD, was used to induce intestinal epithelial cell injury, and study the effects of AMP-18 on apoptosis and the cell cycle. An apoptosis array used to search for targets of AMP-18 in cells exposed to TNF-α identified the cyclin-dependent kinase inhibitor p21 WAF1/CIP1. Treatment with AMP-18 blunted increases in p21 expression and apoptosis, while reversing disturbed cell cycle kinetics induced by TNF-α. AMP-18 appears to act through PI3K/AKT pathways to increase p21 phosphorylation, thereby reducing its nuclear accumulation to overcome the antiproliferative effects of TNF-α. In vitamin D receptor-deficient mice with TNBS-induced IBD, the observed increase in p21 expression in colonic epithelial cells was suppressed by treatment with AMP peptide. The results indicate that AMP-18 can maintain and/or restore the homeostatic balance between proliferation and apoptosis in intestinal epithelial cells to protect and repair mucosal barrier homeostasis and function, suggesting a therapeutic role in IBD.

18 CFR 415.21 - Class II projects.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Class II projects. 415.21 Section 415.21 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION... flooded, would pollute the waters of the basin or threaten damage to off-site areas, including, without...

21 CFR 341.18 - Expectorant active ingredient.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Expectorant active ingredient. 341.18 Section 341.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE COLD, COUGH, ALLERGY, BRONCHODILATOR, AND ANTIASTHMATIC DRUG PRODUCTS FOR OVER-THE...

21 CFR 346.18 - Astringent active ingredients.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Astringent active ingredients. 346.18 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.18 Astringent active ingredients. The active ingredient of the product consists of any of the following when...

21 CFR 346.18 - Astringent active ingredients.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Astringent active ingredients. 346.18 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.18 Astringent active ingredients. The active ingredient of the product consists of any of the following when...

21 CFR 346.18 - Astringent active ingredients.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Astringent active ingredients. 346.18 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.18 Astringent active ingredients. The active ingredient of the product consists of any of the following when...

21 CFR 346.18 - Astringent active ingredients.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Astringent active ingredients. 346.18 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.18 Astringent active ingredients. The active ingredient of the product consists of any of the following when...

21 CFR 346.18 - Astringent active ingredients.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Astringent active ingredients. 346.18 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.18 Astringent active ingredients. The active ingredient of the product consists of any of the following when...

21 CFR 501.18 - Misbranding of animal food.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Misbranding of animal food. 501.18 Section 501.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ANIMAL FOOD LABELING General Provisions § 501.18 Misbranding of...

21 CFR 501.18 - Misbranding of animal food.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Misbranding of animal food. 501.18 Section 501.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ANIMAL FOOD LABELING General Provisions § 501.18 Misbranding of...

21 CFR 501.18 - Misbranding of animal food.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Misbranding of animal food. 501.18 Section 501.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ANIMAL FOOD LABELING General Provisions § 501.18 Misbranding of...

21 CFR 501.18 - Misbranding of animal food.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Misbranding of animal food. 501.18 Section 501.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ANIMAL FOOD LABELING General Provisions § 501.18 Misbranding of...

21 CFR 501.18 - Misbranding of animal food.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Misbranding of animal food. 501.18 Section 501.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ANIMAL FOOD LABELING General Provisions § 501.18 Misbranding of...

18 CFR 1b.21 - Enforcement hotline.

Code of Federal Regulations, 2011 CFR

2011-04-01

... by calling (202) 502-8390 or 1-888-889-8030 (toll free), by e-mail at [email protected], or writing to... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Enforcement hotline. 1b.21 Section 1b.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION...

30 CFR 18.21 - Machines equipped with powered dust collectors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Machines equipped with powered dust collectors. 18.21 Section 18.21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT AND ACCESSORIES...

18 CFR 300.21 - Final confirmation and approval.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Final confirmation and approval. 300.21 Section 300.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... reasonable number of years after first meeting the Administrator's other costs. (ii) The rates must be based...

18 CFR 300.21 - Final confirmation and approval.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Final confirmation and approval. 300.21 Section 300.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... reasonable number of years after first meeting the Administrator's other costs. (ii) The rates must be based...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 201.18 - Drugs; significance of control numbers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Drugs; significance of control numbers. 201.18 Section 201.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING General Labeling Provisions § 201.18 Drugs; significance of control...

21 CFR 71.18 - Petition for exemption from certification.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Petition for exemption from certification. 71.18 Section 71.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVE PETITIONS General Provisions § 71.18 Petition for exemption from certification. A...

21 CFR 71.18 - Petition for exemption from certification.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Petition for exemption from certification. 71.18 Section 71.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVE PETITIONS General Provisions § 71.18 Petition for exemption from certification. A...

21 CFR 71.18 - Petition for exemption from certification.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Petition for exemption from certification. 71.18 Section 71.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVE PETITIONS General Provisions § 71.18 Petition for exemption from certification. A...

21 CFR 71.18 - Petition for exemption from certification.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Petition for exemption from certification. 71.18 Section 71.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVE PETITIONS General Provisions § 71.18 Petition for exemption from certification. A...

Measurement of the reaction 18O(α,n)21Ne

NASA Astrophysics Data System (ADS)

Best, A.; Falahat, S.; Görres, J.; Couder, M.; deBoer, R.; Güray, R. T.; Kontos, A.; Kratz, K.-L.; LeBlanc, P. J.; Li, Q.; O'Brien, S.; Özkan, N.; Sonnabend, K.; Talwar, R.; Uberseder, E.; Wiescher, M.

2013-04-01

Background: The reaction 18O(α,n)21Ne is a part of the reaction chains leading to the production of 19F and 22Ne during He burning in low-mass and massive AGB stars, respectively. Additionally, it has been observed as a strong background source in the measurement of other (α,n) reactions.Purpose: Previously low-energy 18O(α,n)21Ne cross section data have only been available in a non-peer-reviewed form. An improved measurement of this reaction has been done to both clarify its astrophysical influence as well as to provide background yield data for future (α,n) experiments.Method: The 18O(α,n(0+1)) reaction has been measured with a moderating neutron detector. In addition the (α,n1γ) channel has been measured independently by observation of the characteristic 350.7 keV γ transition in 21Ne. The reaction cross section at energies above Eα=1100 keV was determined by a simultaneous R-matrix fit to both channels. The strengths of the two lowest-energy resonances at Eα=959 keV and Eα=1066 keV were analyzed separately using individual Breit-Wigner fits.Results: The cross section of both reaction channels, 18O(α,n0)21Ne and 18O(α,n1γ)21Ne, was determined from the threshold energies at 851 keV and 1280 keV, respectively, to 2300 keV. A new reaction rate has been deduced for the temperature range of 0.1 GK to 10 GK. A previously reported resonance at Eα=888 keV is explained as background from the contaminant reaction 17O(α,n)20Ne.Conclusions: In general, our reaction rate is slightly lower than the reaction rates in recent compilations. At temperatures below 0.2 GK the present rate is significantly lower because it could be shown that the lowest reported resonance is background from the reaction 17O(α,n)20Ne that has been wrongly assigned to 18O(α,n)21Ne.

18 CFR 1312.21 - Surveys and schedules.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Surveys and schedules... OF ARCHAEOLOGICAL RESOURCES: UNIFORM REGULATIONS § 1312.21 Surveys and schedules. (a) The Secretaries... Authority will develop plans for surveying lands under each agency's control to determine the nature and...

18 CFR 1312.21 - Surveys and schedules.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Surveys and schedules... OF ARCHAEOLOGICAL RESOURCES: UNIFORM REGULATIONS § 1312.21 Surveys and schedules. (a) The Secretaries... Authority will develop plans for surveying lands under each agency's control to determine the nature and...

18 CFR 1312.21 - Surveys and schedules.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Surveys and schedules... OF ARCHAEOLOGICAL RESOURCES: UNIFORM REGULATIONS § 1312.21 Surveys and schedules. (a) The Secretaries... Authority will develop plans for surveying lands under each agency's control to determine the nature and...

18 CFR 1312.21 - Surveys and schedules.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Surveys and schedules... OF ARCHAEOLOGICAL RESOURCES: UNIFORM REGULATIONS § 1312.21 Surveys and schedules. (a) The Secretaries... Authority will develop plans for surveying lands under each agency's control to determine the nature and...

18 CFR 1312.21 - Surveys and schedules.

Code of Federal Regulations, 2011 CFR

2011-04-01

... required by 16 U.S.C. 470 et seq. Survey plans prepared under this section will be designed to comply with... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Surveys and schedules... OF ARCHAEOLOGICAL RESOURCES: UNIFORM REGULATIONS § 1312.21 Surveys and schedules. (a) The Secretaries...

18 CFR 3a.21 - Authority to downgrade and declassify.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Authority to downgrade and declassify. 3a.21 Section 3a.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION Declassification and...

18 CFR 3a.21 - Authority to downgrade and declassify.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Authority to downgrade and declassify. 3a.21 Section 3a.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION Declassification and...

18 CFR 3a.21 - Authority to downgrade and declassify.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Authority to downgrade and declassify. 3a.21 Section 3a.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION Declassification and...

18 CFR 3a.21 - Authority to downgrade and declassify.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Authority to downgrade and declassify. 3a.21 Section 3a.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION Declassification and...

18 CFR 366.21 - Accounts and records of holding companies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Accounts and records of holding companies. 366.21 Section 366.21 Conservation of Power and Water Resources FEDERAL ENERGY..., FEDERAL POWER ACT AND NATURAL GAS ACT BOOKS AND RECORDS Accounting and Recordkeeping Under PUHCA 2005, the...

(Tenth symposium on microdosimetry, Rome, Italy; Department of Energy/Commission of European Communities workshop, Rome, Italy; and visit to Neuherberg, W. Germany, May 21--June 3, 1989): Foreign trip report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wright, H.A.

1989-06-15

Report of Harvel A. Wright, to participate in the Tenth Symposium on Microdosimetry in Rome, Italy, May 21-26, 1989; to participate in a Department of Energy/Commission of European Communities (DOE/CEC) Workshop on Long-Term Research Needs and Priorities in Microdosimetry, held in Rome following the microdosimetry symposium; and to visit the Gesellschaft fur Strahlen- and Umweltforschung (GSF) in Neuherberg, FRG, to carry out collaborative research with Dr. H.G. Paretzke.

21 CFR 1305.18 - Return of unused DEA Forms 222.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Return of unused DEA Forms 222. 1305.18 Section... II CONTROLLED SUBSTANCES DEA Form 222 § 1305.18 Return of unused DEA Forms 222. If the registration... business or professional practice, or changes the name or address as shown on the purchaser's registration...

21 CFR 1305.18 - Return of unused DEA Forms 222.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Return of unused DEA Forms 222. 1305.18 Section... II CONTROLLED SUBSTANCES DEA Form 222 § 1305.18 Return of unused DEA Forms 222. If the registration... substances for which the purchaser is registered, the purchaser must return all unused DEA Forms 222 to the...

18 CFR 2.1 - Initial notice; service; and information copies of formal documents.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Initial notice; service; and information copies of formal documents. 2.1 Section 2.1 Conservation of Power and Water Resources... Order 463, 37 FR 28054, Dec. 20, 1972; 38 FR 3192, Feb. 2, 1973; 44 FR 34941, June 18, 1979; 45 FR 21224...

18 CFR 2.1 - Initial notice; service; and information copies of formal documents.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Initial notice; service; and information copies of formal documents. 2.1 Section 2.1 Conservation of Power and Water Resources...; 38 FR 3192, Feb. 2, 1973; 44 FR 34941, June 18, 1979; 45 FR 21224, Apr. 1, 1980; Order 541, 57 FR...

18 CFR 2.1 - Initial notice; service; and information copies of formal documents.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Initial notice; service; and information copies of formal documents. 2.1 Section 2.1 Conservation of Power and Water Resources...; 38 FR 3192, Feb. 2, 1973; 44 FR 34941, June 18, 1979; 45 FR 21224, Apr. 1, 1980; Order 541, 57 FR...

18 CFR 2.1 - Initial notice; service; and information copies of formal documents.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Initial notice; service; and information copies of formal documents. 2.1 Section 2.1 Conservation of Power and Water Resources...; 38 FR 3192, Feb. 2, 1973; 44 FR 34941, June 18, 1979; 45 FR 21224, Apr. 1, 1980; Order 541, 57 FR...

18. CABLE CAR #21, DETAIL OF CAR COMING OUT OF ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. CABLE CAR #21, DETAIL OF CAR COMING OUT OF LOADING AREA OF CAR DUMP BUILDING - Pennsylvania Railroad, Canton Coal Pier, Clinton Street at Keith Avenue (Canton area), Baltimore, Independent City, MD

Mapping the origins of Imperial Roman workers (1st-4th century CE) at Vagnari, Southern Italy, using 87 Sr/86 Sr and δ18 O variability.

PubMed

Emery, Matthew V; Stark, Robert J; Murchie, Tyler J; Elford, Spencer; Schwarcz, Henry P; Prowse, Tracy L

2018-04-18

We obtained the oxygen and strontium isotope composition of teeth from Roman period (1st to 4th century CE) inhabitants buried in the Vagnari cemetery (Southern Italy), and present the first strontium isotope variation map of the Italian peninsula using previously published data sets and new strontium data. We test the hypothesis that the Vagnari population was predominantly composed of local individuals, instead of migrants originating from abroad. We analyzed the oxygen ( 18 O/ 16 O) and strontium ( 87 Sr/ 86 Sr) isotope composition of 43 teeth. We also report the 87 Sr/ 86 Sr composition of an additional 13 molars, 87 Sr/ 86 Sr values from fauna (n = 10), and soil (n = 5) samples local to the area around Vagnari. The 87 Sr/ 86 Sr variation map of Italy uses 87 Sr/ 86 Sr values obtained from previously published data sources from across Italy (n = 199). Converted tooth carbonate (δ 18 O DW ) and 87 Sr/ 86 Sr data indicate that the majority of individuals buried at Vagnari were local to the region. ArcGIS bounded Inverse Distance Weighting (IDW) interpolation of the pan-Italian 87 Sr/ 86 Sr data set approximates the expected 87 Sr/ 86 Sr range of Italy's geological substratum, producing the first strontium map of the Italian peninsula. Results suggest that only 7% of individuals buried at Vagnari were born elsewhere and migrated to Vagnari, while the remaining individuals were either local to Vagnari (58%), or from the southern Italian peninsula (34%). Our results are consistent with the suggestion that Roman Imperial lower-class populations in southern Italy sustained their numbers through local reproduction measures, and not through large-scale immigration from outside the Italian peninsula. © 2018 Wiley Periodicals, Inc.

21 CFR 822.18 - How will I be notified of your decision?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false How will I be notified of your decision? 822.18 Section 822.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES POSTMARKET SURVEILLANCE FDA Review and Action § 822.18 How will I be notified of...

21 CFR 822.18 - How will I be notified of your decision?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false How will I be notified of your decision? 822.18 Section 822.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES POSTMARKET SURVEILLANCE FDA Review and Action § 822.18 How will I be notified of...

21 CFR 822.18 - How will I be notified of your decision?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false How will I be notified of your decision? 822.18 Section 822.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES POSTMARKET SURVEILLANCE FDA Review and Action § 822.18 How will I be notified of...

21 CFR 822.18 - How will I be notified of your decision?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false How will I be notified of your decision? 822.18 Section 822.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES POSTMARKET SURVEILLANCE FDA Review and Action § 822.18 How will I be notified of...

21 CFR 822.18 - How will I be notified of your decision?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false How will I be notified of your decision? 822.18 Section 822.18 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES POSTMARKET SURVEILLANCE FDA Review and Action § 822.18 How will I be notified of...

Trophic transfer of persistent organic pollutants through a pelagic food web: The case of Lake Como (Northern Italy).

PubMed

Mazzoni, Michela; Boggio, Emanuela; Manca, Marina; Piscia, Roberta; Quadroni, Silvia; Bellasi, Arianna; Bettinetti, Roberta

2018-05-30

Despite DDT and PCB having been banned for about 40 years, they are still detectable in the environment. In the present research we specifically investigated the trophic transfer of these organochlorine contaminants (OC) through a pelagic food web of a deep lake in Northern Italy (Lake Como) over time. Zooplankton and fish were sampled each season of a year and OC concentrations and the carbon and nitrogen isotopic ratios were measured. By using stable isotopes, the direct trophic relationship between pelagic zooplankton and zooplanktivorous fish was confirmed for Alosa agone only in summer. Based on this result, the biomagnification factor normalized on the trophic level (BMF TL ) for organic contaminants was calculated. BMF TL values were within the range 0.9-1.9 for DDT isomers and 1.6-4.9 for some PCB congeners (PCB 95, PCB 101, PCB 149, PCB 153, PCB 138 - present both in zooplankton and in fish and representing >60% of the PCB contamination), confirming the biomagnification of these compounds in one of the two zooplanktivorous fish species of the lake. Copyright © 2018. Published by Elsevier B.V.

Epidemiology of human toxocariasis in northern Italy.

PubMed

Genchi, C; Di Sacco, B; Gatti, S; Sangalli, G; Scaglia, M

1990-12-01

Sera from both clinically healthy adults (2112) and adult patients (471) were tested to assess the main risk factors for Toxocara infection in humans in Northern Italy. The patient group included 257 adult epileptics, 76 Strongyloides stercoralis-infected adult patients and 142 institutionalized mentally retarded adult patients. The overall seroprevalence in healthy population was 3.98%. No significant differences in seroprevalence were observed for sex, residence (urban or rural) or dog ownership, while seroprevalence significantly increased with age (18- greater than 51 years). Highest seroprevalence values were found in outdoor or soil-related workers. The seroprevalence was 4.35% in adult epileptics, 9.21% in Strongyloides stercoralis-infected patients and 14.47%-10.61% among institutionalized mentally retarded patients. These findings suggest that the prevalent source of human toxocariasis is the environmental contamination by infectious eggs of the parasite.

A foetus with 18p11.32-q21.2 duplication and Xp22.33-p11.1 deletion derived from a maternal reciprocal translocation t(X;18)(q13;q21.3).

PubMed

Chen, Jun-Kun; Liu, Ping; Hu, Li-Qin; Xie, Qing; Huang, Quan-Fei; Liu, Hai-Liang

2018-01-01

Non-invasive prenatal testing (NIPT) evaluates circulating cell-free DNA (cfDNA) and has been widely applied, with highly accurate results for detecting foetal trisomies 21, 18 and 13. Recently, increasing attention has been paid to the clinical application of the non-invasive detection of foetal sub-chromosomal duplications and deletions beyond common aneuploidies. A 32-year-old healthy pregnant woman was referred to the Medical Genetic Centre of Ganzhou Maternal and Child Health Care Hospital. As routine practice, ultrasound examination at a gestational age of 16 weeks showed that the foetus is normal. To avoid invasive prenatal diagnosis procedures, an NIPT was offered to further screen for common foetal chromosomal abnormalities. The result showed that there was an approximately 50.94 Mb duplication in p11.32-q21.2 of chromosome 18 and an approximately 58.46 Mb deletion in p22.33-p11.1 of chromosome X. In addition, the chromosome karyotypes of the parents and foetus were also analysed. Chromosome karyotype analysis results showed that foetal karyotype was 46,X,der(18), the maternal karyotype was 46,XX,t(X;18)(q13;q21.3), and the paternal karyotype revealed no obvious abnormality. In this case, we successfully detected a healthy pregnant woman with balanced translocation X;18(q13;q21.3) and described the foetal karyotype as 46,X,der(18)t(X;18)(q11;q21.1)mat. Our report illustrated these cases which present complex X;autosome balance translocation and X;autosome unbalance translocation which may contribute to severe clinical phenotypes. In addition, our report also proved that the interruption of genes in the Xq critical region is not only reason of primary infertility. Finally, we prompted that NIPT might play a role in the first trimester screening of sub-chromosomal rearrangement.

18. Historic plan of Building 100 control room. March 21, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Historic plan of Building 100 control room. March 21, 1956. NASA GRC drawing number CE-101736. (On file at NASA Glenn Research Center). - Rocket Engine Testing Facility, GRC Building No. 100, NASA Glenn Research Center, Cleveland, Cuyahoga County, OH

Mt. Vesuvius, Italy

NASA Image and Video Library

2001-10-22

This ASTER image of Mt. Vesuvius Italy was acquired September 26, 2000, and covers an area of 36 by 45 km. Vesuvius overlooks the city of Naples and the Bay of Naples in central Italy. In 79 AD, Vesuvius erupted cataclysmically, burying all of the surrounding cites with up to 30 m of ash. The towns of Pompeii and Herculanaeum were rediscovered in the 18th century, and excavated in the 20th century. They provide a snapshot of Roman life from 2000 years ago: perfectly preserved are wooden objects, food items, and the casts of hundreds of victims. Vesuvius is intensively monitored for potential signs of unrest that could signal the beginning of another eruption. The image is centered at 40.8 degrees north latitude, 14.4 degrees east longitude. http://photojournal.jpl.nasa.gov/catalog/PIA11091

Climatic and anthropogenic forcing of prehistorical vegetation succession and fire dynamics in the Lago di Como area (N-Italy, Insubria)

NASA Astrophysics Data System (ADS)

Martinelli, Elisa; Michetti, Alessandro Maria; Colombaroli, Daniele; Mazzola, Eleonora; Motella De Carlo, Sila; Livio, Franz; Gilli, Adrian; Ferrario, Maria Francesca; Höbig, Nicole; Brunamonte, Fabio; Castelletti, Lanfredo; Tinner, Willy

2017-04-01

Combined pollen, charcoal and modeling evidence from the Insubria Region suggests that fire was a major driver of late Holocene vegetation change. However, the extent and timing of fire response dynamics are not clear yet. We use lacustrine sediments from Lago di Como (N-Italy, S-Alps) to assess if the reconstructed vegetation and fire dynamics were relevant at large scales and if they coincided in time with those observed at smaller sites. The lake, due to its size (142 km2) and economic potential, was very attractive for early land use and human presence in this area is well documented since ca. 10,000 yrs ago (Mesolithic). We used pollen, plant macrofossils and charcoal to reconstruct the vegetation composition and fire activity. During the Younger Dryas and the Early Holocene until ca. 8000 cal BP natural dynamics prevailed. Subsequently, land use and slash-and-burn activities increased at the Mesolithic-Neolithic transition and became widespread around ca. 6500 cal BP. Microscopic charcoal and numerical analyses demonstrate that anthropogenic fires had a determinant influence on long-term vegetation dynamics at regional scales in Insubria. Microscopic charcoal and pollen and spores indicative of land use show that human pressure intensified after ca. 5300 cal yr BP and even more since ca. 4300 cal yr BP. Our results suggest that important species which disappeared or were strongly reduced by land use and fire (e.g. Abies alba, Tilia, Ulmus) will potentially reestablish in the Lago di Como area and elsewhere in Insubria, if land abandonment initiated in the 1950s will continue.

[Prevalence of congenital abnormalities identified in fetuses with 13, 18 and 21 chromosomal trisomy].

PubMed

Emer, Caroline Soares Cristofari; Duque, Julio Alejandro Peña; Müller, Ana Lúcia Letti; Gus, Rejane; Sanseverino, Maria Teresa Vieira; da Silva, André Anjos; Magalhães, José Antonio de Azevedo

2015-07-01

To describe the prevalence of malformations found in fetuses with trisomy of chromosomes 13, 18 and 21 by identifying the most frequent within each condition. A retrospective cross-sectional study with the analysis of trisomy cases of chromosomes 13, 18 and 21 diagnosed through fetal karyotype obtained by amniocentesis/cordocentesis, between October 1994 and May 2014, at a Teaching Hospital in Brazil Southern Region. Malformations identified through morphological ultrasonography were described and, subsequently, confirmed in newborn examinations and/or fetal autopsy. The results were analyzed using Fisher's test and analysis of variance (ANOVA), with a 5% level of significance (p=0.05). Sixty-nine cases of trisomy were diagnosed among 840 exams; nine were excluded due to outcome outside Hospital de Clínicas de Porto Alegre or incomplete records, remaining 60 cases (nine cases of chromosome 13 trisomy, 26 of chromosome 18, and 25 of chromosome 21). In all three groups, heart disease occurred in most cases; the ventricular septal defect was more prevalent and occurred in 66.7% of the trisomy 13 group. Gastrointestinal abnormalities were more prevalent in the trisomy 18 group, especially omphalocele (38.5%; p<0.01). Genitourinary anomalies were more significantly frequent in the trisomy 13 group (pyelectasis, 55.6% - p<0.01; ambiguous genitalia, 33.3% - p=0.01). Central nervous system defects were identified in all cases of trisomy 13. Facial cracks were significantly more prevalent among fetuses with trisomy 13 (66.7%; p<0.01). Hand and feet malformations significantly differed among the trisomy groups. Hand defects occurred in 50% of trisomy 18 cases, and in 44.4% of all trisomy 13 cases (p<0.01); congenital clubfoot was more common in the trisomy 18 group, being detected in 46.2% of fetuses (p<0.01). The abnormalities were found in 50.9, 27.3 and 21.7% of trisomy 18, 13 and 21 cases respectively. Many fetal malformations identified at ultrasound are suggestive of

THE 3rd SCHIZOPHRENIA INTERNATIONAL RESEARCH SOCIETY CONFERENCE, 14-18 APRIL 2012, FLORENCE, ITALY: SUMMARIES OF ORAL SESSIONS

PubMed Central

Abbs, Brandon; Achalia, Rashmin M; Adelufosi, Adegoke O; Aktener, Ahmet Yiğit; Beveridge, Natalie J; Bhakta, Savita G; Blackman, Rachael K; Bora, Emre; Byun, MS; Cabanis, Maurice; Carrion, Ricardo; Castellani, Christina A; Chow, Tze Jen; Dmitrzak-Weglarz, M; Gayer-Anderson, Charlotte; Gomes, Felipe V; Haut, Kristen; Hori, Hiroaki; Kantrowitz, Joshua T; Kishimoto, Taishiro; Lee, Frankie HF; Lin, Ashleigh; Palaniyappan, Lena; Quan, Meina; Rubio, Maria D; Ruiz de Azúa, Sonia; Sahoo, Saddichha; Strauss, Gregory P; Szczepankiewicz, Aleksandra; Thompson, Andrew D; Trotta, Antonella; Tully, Laura M; Uchida, Hiroyuki; Velthorst, Eva; Young, Jared W; O’Shea, Anne; DeLisi, Lynn E.

2013-01-01

The 3rd Schizophrenia International Research Society Conference was held in Florence, Italy, April 14-18, 2012.and this year had as its emphasis, “The Globalization of Research”. Student travel awardees served as rapporteurs for each oral session and focused their summaries on the most significant findings that emerged and the discussions that followed. The following report is a composite of these summaries. We hope that it will provide an overview for those who were present, but could not participate in all sessions, and those who did not have the opportunity to attend, but who would be interested in an update on current investigations ongoing in the field of schizophrenia research. PMID:22910407

30 CFR 18.21 - Machines equipped with powered dust collectors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Machines equipped with powered dust collectors... Construction and Design Requirements § 18.21 Machines equipped with powered dust collectors. Powered dust collectors on machines submitted for approval shall meet the applicable requirements of Part 33 of this...

21. Detail of steel ribs at south wall, T18; Note ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

21. Detail of steel ribs at south wall, T-18; Note composition of ribs--two steel channels welded together - Advance Base Depot Davisville, Building T-17, Ninth Street southeast of Davisville Road, Davisville, Washington County, RI

18 CFR 2.1 - Initial notice; service; and information copies of formal documents.

Code of Federal Regulations, 2011 CFR

2011-04-01

...] (iii) Hydroelectric, Federal Power Act. (A) Applications for preliminary permits pursuant to section 4... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Initial notice; service; and information copies of formal documents. 2.1 Section 2.1 Conservation of Power and Water Resources...

Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer

PubMed Central

Hua, Rui-Xi; Du, Yi-Qun; Huang, Ming-Zhu; Liu, Yong; Cheng, Yu Fang; Guo, Wei-Jian

2016-01-01

Mel-18, a polycomb group protein, has been reported to act as a tumor suppressor and be down-regulated in several human cancers including gastric cancer. It was also found that Mel-18 negatively regulates self-renewal of hematopoietic stem cells and breast cancer stem cells (CSCs). This study aimed to clarify its role in gastric CSCs and explore the mechanisms. We found that low-expression of Mel-18 was correlated with poor prognosis and negatively correlated with overexpression of stem cell markers Oct4, Sox2, and Gli1 in 101 gastric cancer tissues. Mel-18 was down-regulated in cultured spheroid cells, which possess CSCs, and overexpression of Mel-18 inhibits cells sphere-forming ability and tumor growth in vivo. Besides, Mel-18 was lower-expressed in ovary metastatic lesions compared with that in primary lesions of gastric cancer, and Mel-18 overexpression inhibited the migration ability of gastric cancer cells. Interestingly, overexpression of Mel-18 resulted in down-regulation of miR-21 in gastric cancer cells and the expression of Mel-18 was negatively correlated with the expression of miR-21 in gastric cancer tissues. Furthermore, miR-21 overexpression partially restored sphere-forming ability, migration potential and chemo-resistance in Mel-18 overexpressing gastric cancer cells. These results suggests Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer cells. PMID:27542229

Investigation of the thermonuclear 18Ne(α,p)21Na reaction rate via resonant elastic scattering of 21Na + p

NASA Astrophysics Data System (ADS)

Zhang, L. Y.; He, J. J.; Parikh, A.; Xu, S. W.; Yamaguchi, H.; Kahl, D.; Kubono, S.; Mohr, P.; Hu, J.; Ma, P.; Chen, S. Z.; Wakabayashi, Y.; Wang, H. W.; Tian, W. D.; Chen, R. F.; Guo, B.; Hashimoto, T.; Togano, Y.; Hayakawa, S.; Teranishi, T.; Iwasa, N.; Yamada, T.; Komatsubara, T.; Zhang, Y. H.; Zhou, X. H.

2014-01-01

The 18Ne(α,p)21Na reaction is thought to be one of the key breakout reactions from the hot CNO cycles to the rp process in type I x-ray bursts. In this work, the resonant properties of the compound nucleus 22Mg have been investigated by measuring the resonant elastic scattering of 21Na + p. An 89-MeV 21Na radioactive beam delivered from the CNS Radioactive Ion Beam Separator bombarded an 8.8 mg/cm2 thick polyethylene (CH2)n target. The 21Na beam intensity was about 2×105 pps, with a purity of about 70% on target. The recoiled protons were measured at the center-of-mass scattering angles of θc.m.≈175.2∘, 152.2∘, and 150.5∘ by three sets of ΔE-E telescopes, respectively. The excitation function was obtained with the thick-target method over energies Ex(22Mg)=5.5-9.2 MeV. In total, 23 states above the proton-threshold in 22Mg were observed, and their resonant parameters were determined via an R-matrix analysis of the excitation functions. We have made several new Jπ assignments and confirmed some tentative assignments made in previous work. The thermonuclear 18Ne(α,p)21Na rate has been recalculated based on our recommended spin-parity assignments. The astrophysical impact of our new rate has been investigated through one-zone postprocessing x-ray burst calculations. We find that the 18Ne(α,p)21Na rate significantly affects the peak nuclear energy generation rate, reaction fluxes, and onset temperature of this breakout reaction in these astrophysical phenomena.

Italy of censuses.

PubMed

Rey, G M

1983-06-01

To supplement census data on Italy's economy, Istat conducted a sample survey of 2% of households. This paper reports survey findings in 3 areas: age structure of the population, employment and unemployment patterns by region, and structure of the productive system. Those over age 65 years have increased from 11% of the population in 1971 to 13% in 1981 and are forecast to constitute 14.5% in 1991. Women accounted for 51.3% of the total population in 1981 but 58.5% of those over age 65. 12% of households have a member over age 75. The 0-14 year age group has declined from 24.4% of the population in 1971 to 21.5% in 1981 and is projected to comprise 17.4% in 1991. The labor force activity rate was 39.8% in 1981. Unemployment was set at 14.7% in the census sample compared with 9.1% in Istat's quarterly survey of the labor force. 60% of the difference between these 2 figures was accounted for by Campania, Sicily, Puglia, Calabria, and Latium. These 5 regions, which account for only 30% of total employment, are the areas with the most acute employment problems and highest proportions of casual employment in agriculture and traditional services. Agriculture accounted for 22% of total unemployment, construction for 18.5%, and traditional industry for 14%--percentages that are higher than the share of total employment represented by these sectors. In the South, 20.4% of employment is in agriculture, 18.1% in industry, 12.6% in construction, and 48.9% in services. The average worker in the South supports 3.3 persons compared with 2.5 persons in the North. Survey results indicate a substantial shift in the sectoral composition of employment as well as a change in the size of productive units. There has been an increase in the highly specialized components of the economy, including services to firms. The average size of factories has declined, with a proliferation of small and medium sized units. These findings suggest a need to broaden and deepen Italy's industrial base

Fleet Mooring Underwater Inspection Report La Maddalena, Italy.

DTIC Science & Technology

1981-12-01

Peg Top mooring buoys at the bow at the NATO Naval Facility, St. Stefano , Sardinia, Italy. The ship using the mooring is moored at the stern to the...LAT: NSO LA MADDALENA NORTH RISER/MED MOOR LON:SANTO STEFANO ,ISardinia, Italy ii DATE DIVERS U 1WATER DEPTH SUPERVISOR INITIALS 5. INSPECTION 18-25 Sep...0) 0 蟙 W. .-. MOORING INSPECTION REPORT Page 3 of 3 1. FACILITY 2. MOORING NO. 13. TYPE/CLASSMOORING 4. LAT.RISER/MD MOOR SANTO STEFANO , NSO LA

Mt. Vesuvius, Italy

NASA Technical Reports Server (NTRS)

2001-01-01

This ASTER image of Mt. Vesuvius Italy was acquired September 26, 2000, and covers an area of 36 by 45 km. Vesuvius overlooks the city of Naples and the Bay of Naples in central Italy. In 79 AD, Vesuvius erupted cataclysmically, burying all of the surrounding cites with up to 30 m of ash. The towns of Pompeii and Herculanaeum were rediscovered in the 18th century, and excavated in the 20th century. They provide a snapshot of Roman life from 2000 years ago: perfectly preserved are wooden objects, food items, and the casts of hundreds of victims. Vesuvius is intensively monitored for potential signs of unrest that could signal the beginning of another eruption. The image is centered at 40.8 degrees north latitude, 14.4 degrees east longitude.

The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

Mount Vesuvius, Italy

NASA Technical Reports Server (NTRS)

2002-01-01

This Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) image of Mt. Vesuvius, Italy was acquired September 26, 2000. The full-size false-color image covers an area of 36 by 45 km. Vesuvius overlooks the city of Naples and the Bay of Naples in central Italy. (Popocatepetl and Mount Fuji are other volcanos surrounded by dense urban areas.) In 79 AD, Vesuvius erupted cataclysmically, burying all of the surrounding cites with up to 30 m of ash. The towns of Pompeii and Herculanaeum were rediscovered in the 18th century, and excavated in the 20th century. They provide a snapshot of Roman life from 2000 years ago: perfectly preserved are wooden objects, food items, and the casts of hundreds of victims. Vesuvius is intensively monitored for potential signs of unrest that could signal the beginning of another eruption. Image courtesy NASA/GSFC/MITI/ERSDAC/JAROS, and U.S./Japan ASTER Science Team

Noninvasive prenatal testing of trisomies 21 and 18 by massively parallel sequencing of maternal plasma DNA in twin pregnancies.

PubMed

Huang, Xuan; Zheng, Jing; Chen, Min; Zhao, Yangyu; Zhang, Chunlei; Liu, Lifu; Xie, Weiwei; Shi, Shuqiong; Wei, Yuan; Lei, Dongzhu; Xu, Chenming; Wu, Qichang; Guo, Xiaoling; Shi, Xiaomei; Zhou, Yi; Liu, Qiufang; Gao, Ya; Jiang, Fuman; Zhang, Hongyun; Su, Fengxia; Ge, Huijuan; Li, Xuchao; Pan, Xiaoyu; Chen, Shengpei; Chen, Fang; Fang, Qun; Jiang, Hui; Lau, Tze Kin; Wang, Wei

2014-04-01

The objective of this study is to assess the performance of noninvasive prenatal testing for trisomies 21 and 18 on the basis of massively parallel sequencing of cell-free DNA from maternal plasma in twin pregnancies. A double-blind study was performed over 12 months. A total of 189 pregnant women carrying twins were recruited from seven hospitals. Maternal plasma DNA sequencing was performed to detect trisomies 21 and 18. The fetal karyotype was used as gold standard to estimate the sensitivity and specificity of sequencing-based noninvasive prenatal test. There were nine cases of trisomy 21 and two cases of trisomy 18 confirmed by karyotyping. Plasma DNA sequencing correctly identified nine cases of trisomy 21 and one case of trisomy 18. The discordant case of trisomy 18 was an unusual case of monozygotic twin with discordant fetal karyotype (one normal and the other trisomy 18). The sensitivity and specificity of maternal plasma DNA sequencing for fetal trisomy 21 were both 100% and for fetal trisomy 18 were 50% and 100%, respectively. Our study further supported that sequencing-based noninvasive prenatal testing of trisomy 21 in twin pregnancies could be achieved with a high accuracy, which could effectively avoid almost 95% of invasive prenatal diagnosis procedures. © 2013 John Wiley & Sons, Ltd.

Brain energy metabolism and neuroinflammation in ageing APP/PS1-21 mice using longitudinal 18F-FDG and 18F-DPA-714 PET imaging.

PubMed

Takkinen, Jatta S; López-Picón, Francisco R; Al Majidi, Rana; Eskola, Olli; Krzyczmonik, Anna; Keller, Thomas; Löyttyniemi, Eliisa; Solin, Olof; Rinne, Juha O; Haaparanta-Solin, Merja

2017-08-01

Preclinical animal model studies of brain energy metabolism and neuroinflammation in Alzheimer's disease have produced conflicting results, hampering both the elucidation of the underlying disease mechanism and the development of effective Alzheimer's disease therapies. Here, we aimed to quantify the relationship between brain energy metabolism and neuroinflammation in the APP/PS1-21 transgenic mouse model of Alzheimer's disease using longitudinal in vivo 18 F-FDG and 18 F-DPA-714) PET imaging and ex vivo brain autoradiography. APP/PS1-21 (TG, n = 9) and wild type control mice (WT, n = 9) were studied longitudinally every third month from age 6 to 15 months with 18 F-FDG and 18 F-DPA-714 with a one-week interval between the scans. Additional TG (n = 52) and WT (n = 29) mice were used for ex vivo studies. In vivo, the 18 F-FDG SUVs were lower and the 18 F-DPA-714 binding ratios relative to the cerebellum were higher in the TG mouse cortex and hippocampus than in WT mice at age 12 to 15 months ( p < 0.05). The ex vivo cerebellum binding ratios supported the results of the in vivo 18 F-DPA-714 studies but not the 18 F-FDG studies. This longitudinal PET study demonstrated decreased energy metabolism and increased inflammation in the brains of APP/PS1-21 mice compared to WT mice.

21 CFR 740.18 - Coal tar hair dyes posing a risk of cancer.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Coal tar hair dyes posing a risk of cancer. 740.18... (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.18 Coal tar hair dyes... coal tar hair dye containing any ingredient listed in paragraph (b) of this section shall bear, in...

Persistent monoclonality after histological remission in gastric mucosa-associated lymphoid tissue lymphoma treated with chemotherapy and/or surgery: influence of t(11;18)(q21;q21).

PubMed

Santón, Almudena; García-Cosio, Mónica; Bellosillo, Beatriz; Rodríguez, Patricia; Cristóbal, Eva; Serrano, Sergio; Besses, Carlos; Abraira, Victor; Salar, Antonio; Montalbán, Carlos

2008-08-01

The purpose of this work was to study retrospectively the molecular response and outcome of 19 gastric mucosa associated lymphoid tissue (MALT) lymphoma patients achieving histological remission after chemotherapy or surgery. Immunoglobulin heavy chain variable (IgV(H)) gene rearrangements were studied by PCR in biopsies obtained at diagnosis and follow-up. Presence of t(11;18)(q21;q21) was studied by FISH or RT-PCR. Sequencing analysis of three t(11;18)(q21;q21) positive and two negative lymphomas with persistent monoclonal IgV(H) rearrangements was also performed. Long-term IgV(H) monoclonality was demonstrated in 11/19 patients (58%); in five of them monoclonal rearrangements were present in all samples throughout the follow-up. Persistent IgV(H) monoclonality was detected a median of 49 months after the achievement of histological response and did not condition histological relapse in most cases. All three t(11;18)(q21;q21) positive patients had maintained IgV(H) monoclonality and sequencing analyses revealed the same mutated IgV(H) alleles in the diagnostic and the follow-up samples. Over half of the patients with gastric MALT lymphoma with histological response after chemotherapy and/or surgery have long-term persistent monoclonality. The presence of t(11;18)(q21;q21) seems to condition long-term persistence of the initial lymphoma clone.trade mark.

Stable isotopes of pedogenic carbonates from the Somma-Vesuvius area, southern Italy, over the past 18 kyr: palaeoclimatic implications

NASA Astrophysics Data System (ADS)

Zanchetta, G.; di Vito, M.; Fallick, A. E.; Sulpizio, R.

2000-12-01

Stable isotopes were measured in the carbonate and organic matter of palaeosols in the Somma-Vesuvius area, southern Italy in order to test whether they are suitable proxy records for climatic and ecological changes in this area during the past 18000 yr. The ages of the soils span from ca. 18 to ca. 3 kyr BP. Surprisingly, the Last Glacial to Holocene climate transition was not accompanied by significant change in 18O of pedogenic carbonate. This could be explained by changes in evaporation rate and in isotope fractionation between water and precipitated carbonate with temperature, which counterbalanced the expected change in isotope composition of meteoric water. Because of the rise in temperature and humidity and the progressive increase in tree cover during the Holocene, the Holocene soil carbonates closely reflect the isotopic composition of meteoric water. A cooling of about 2°C after the Avellino eruption (3.8 ka) accounts for a sudden decrease of about 1 in 18O of pedogenic carbonate recorded after this eruption. The 13C values of organic matter and pedogenic carbonate covary, indicating an effective isotope equilibrium between the organic matter, as the source of CO2, and the pedogenic carbonate. Carbon isotopes suggest prevailing C3 vegetation and negligible mixing with volcanogenic or atmospheric CO2.

Aichivirus in Children with Diarrhea in Northern Italy.

PubMed

Bergallo, Massimiliano; Galliano, Ilaria; Montanari, Paola; Rassu, Marco; Daprà, Valentina

2017-01-01

Since its discovery, Aichivirus (AiV) A has been detected, with an incidence of 0.9-4.1%, primarily when studying outbreaks of diarrhea in children or young adults. In this paper, we report the first detection of AiV in Piedmont, Italy, in pediatric patients. A total of 159 fecal specimens (from 96 males and 63 females) previously screened for rotaviruses, adenoviruses, noroviruses, human parechoviruses, saliviruses, and sapoviruses were collected from infants and children with acute gastroenteritis. The most commonly detected virus was norovirus GII (33.80%), fol lowed by rotavirus (21.30%), astrovirus (18.87%), boca virus (13.92%), sapovirus (10.90%), parechovirus (8%), norovirus GI (6.70%), adenovirus (1%), and salivirus (0.52%). Real-time polymerase chain reaction detected AiV A in 1 (0.62%) case subjects. AiV A was detected in monoinfection only in January. Our results indicate that AiV may be associated with a limited number of diarrhea cases in pediatric patients. © 2018 S. Karger AG, Basel.

Role of congenital rubella reference laboratory: 21-months-surveillance in Liguria, Italy.

PubMed

Canepa, P; Valle, L; Cristina, E; De Florentiis, D; Parodi, V; Banfi, F; Zancolli, M; Durando, P; Icardi, G; Ansaldi, F

2009-12-01

Rubella is generally a mild rush fever disease when acquired in childhood, but when infection occurs during the first months of pregnancy, high risk of trans-placental transmission to the foetus and of congenital anomalies exists. In November 2003, a National Plan for measles and congenital rubella elimination was approved in Italy. The aim was to reduce and maintain Congenital Rubella Syndrome incidence lower than 1 case per 100,000 live births/year by 2007. Since June 2006, Liguria Administrative Region recognized U.O. Hygiene, "San Martino" University Hospital, Genoa, as regional reference laboratory for diagnosis of rubella infection during pregnancy and post-partum. Twenty-one-month virological-surveillance results between April 2007 and December 2008 were reported in terms of demographic data, risk factors, access reasons, clinical picture, vaccination, previous rubella disease, laboratory results of pregnant women and newborns. Since the beginning of surveillance, 65 pregnant women with suspected virus infection and 18 newborns with suspected congenital rubella were followed up. The results of laboratory surveillance highlighted (i) the importance of an early screening, (ii) the suboptimal specificity of chemiluminescent assays, that often yield false positive IgM results and (iii) the fundamental role of second-level laboratory to confirm the serological diagnosis and to detect the virus by molecular techniques.

Italy's Treasures Are in Their Hands

ERIC Educational Resources Information Center

Rocca, Francis X.

2007-01-01

Each year more than 300 applicants vie for 18 slots at the Central Institute of Restoration, the program responsible for the restoration of many of Italy's greatest works of art, and the training of experts in the repair of objects of artistic and/or cultural significance. Successful candidates must demonstrate knowledge of art history, chemistry,…

7 CFR 319.8-21 - Release of cotton and covers after 18 months' storage.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 5 2013-01-01 2013-01-01 false Release of cotton and covers after 18 months' storage... Cotton and Covers Miscellaneous Provisions § 319.8-21 Release of cotton and covers after 18 months' storage. Cotton and covers, the entry of which has been authorized subject to vacuum fumigation or other...

7 CFR 319.8-21 - Release of cotton and covers after 18 months' storage.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 5 2014-01-01 2014-01-01 false Release of cotton and covers after 18 months' storage... Cotton and Covers Miscellaneous Provisions § 319.8-21 Release of cotton and covers after 18 months' storage. Cotton and covers, the entry of which has been authorized subject to vacuum fumigation or other...

7 CFR 319.8-21 - Release of cotton and covers after 18 months' storage.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 5 2011-01-01 2011-01-01 false Release of cotton and covers after 18 months' storage... Cotton and Covers Miscellaneous Provisions § 319.8-21 Release of cotton and covers after 18 months' storage. Cotton and covers, the entry of which has been authorized subject to vacuum fumigation or other...

7 CFR 319.8-21 - Release of cotton and covers after 18 months' storage.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Release of cotton and covers after 18 months' storage... Cotton and Covers Miscellaneous Provisions § 319.8-21 Release of cotton and covers after 18 months' storage. Cotton and covers, the entry of which has been authorized subject to vacuum fumigation or other...

7 CFR 319.8-21 - Release of cotton and covers after 18 months' storage.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 5 2012-01-01 2012-01-01 false Release of cotton and covers after 18 months' storage... Cotton and Covers Miscellaneous Provisions § 319.8-21 Release of cotton and covers after 18 months' storage. Cotton and covers, the entry of which has been authorized subject to vacuum fumigation or other...

18 CFR 2.1b - Availability in contested cases of information acquired by staff investigation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Availability in contested cases of information acquired by staff investigation. 2.1b Section 2.1b Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

18 CFR 2.1b - Availability in contested cases of information acquired by staff investigation.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Availability in contested cases of information acquired by staff investigation. 2.1b Section 2.1b Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

18 CFR 2.1b - Availability in contested cases of information acquired by staff investigation.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Availability in contested cases of information acquired by staff investigation. 2.1b Section 2.1b Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

18 CFR 2.1b - Availability in contested cases of information acquired by staff investigation.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Availability in contested cases of information acquired by staff investigation. 2.1b Section 2.1b Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

Identification and characterisation of TLR18-21 genes in Atlantic salmon (Salmo salar).

PubMed

Lee, P T; Zou, J; Holland, J W; Martin, S A M; Collet, B; Kanellos, T; Secombes, C J

2014-12-01

Teleost fish possess many types of toll-like receptor (TLR) some of which exist in other vertebrate groups and some that do not (ie so-called "fish-specific" TLRs). In this study, we identified in Atlantic salmon (Salmo salar) whole-genome shotgun (WGS) contigs seven TLRs that are not found in mammals, including six types of fish-specific TLRs (one TLR18, one TLR19, and four TLR20 members (two of which are putative soluble forms (s)) and one TLR21. Phylogenetic analysis revealed that teleost TLR19-21 are closely related with murine TLR11-TLR13, whilst teleost TLR18 groups with mammalian TLR1, 2, 6 and 10. A typical TLR protein domain structure was found in all these TLRs with the exception of TLR20b(s) and TLR20c(s). TLR-GFP expression plasmids transfected into SHK-1 cells showed that salmon TLR19, TLR20a and TLR20d were preferentially localised to the intracellular compartment. Real time PCR analysis suggested that salmon TLR19-TLR21 are mainly expressed in immune related organs, such as spleen, head kidney and gills, while TLR18 transcripts are more abundant in muscle. In vitro stimulation of primary head kidney cells with type I IFN, IFNγ and IL-1β had no impact on TLR expression. Infectious salmon anaemia virus (ISAV) infection, in vivo, down-regulated TLR20a, TLR20b(s), TLR20d and TLR21 in infected salmon kidney tissue. In contrast, up-regulation of TLR19 and TLR20a expression was found in posterior kidney in rainbow trout with clinical proliferative kidney disease (PKD). Copyright © 2014 Elsevier Ltd. All rights reserved.

Lake Garda, Italy

NASA Image and Video Library

2001-07-21

This ASTER image was acquired on July 29, 2000 and covers an area of 30 by 57 km in northern Italy. Lake Garda was formed by glaciers during the last Ice Age, and is Italy's largest lake. Lago di Garda lies in the provinces of Verona, Brescia, and Trento, and is 51 kilometers (32 miles) long and from 3 to 18 kilometers (2 to 11 miles) wide. The Sarca is its chief affluent, and the lake is drained southward by the Mincio, which discharges into the Po River. Many villas are situated on its shores. On the peninsula of Sirmione, at the southern end of the lake, are the ruins of a Roman villa and a castle of the Scaligers, an Italian family of the 16th century. The RIGHT image has the land area masked out, and a harsh stretch was applied to the lake values to display variations in sediment load. Also visible are hundreds of boats and their wakes, criss-crossing the lake. The image is centered at 45.6 degrees north latitude, 10.6 degrees east longitude. http://photojournal.jpl.nasa.gov/catalog/PIA02671

Study of Ordering and Properties in Fe-Ga Alloys With 18 and 21 at. pct Ga

NASA Astrophysics Data System (ADS)

Golovin, Igor S.; Dubov, L. Yu.; Funtikov, Yu. V.; Palacheva, V. V.; Cifre, J.; Hamana, D.

2015-03-01

Dynamical mechanical and positron annihilation spectroscopies were applied to study the structure of two Fe-Ga alloys with 18 and 21 at. pct Ga after quenching and subsequent annealing. It was found that the alloy with 18 pct Ga has much better damping capacity (Ψ ≈ 30 pct) than the alloy with 21 pct Ga (Ψ ≈ 5 pct). The reason for that is the ordering of the Ga atoms in Fe-21Ga alloy. Ordering processes in both alloys are studied at heating by differential scanning calorimetry, dilatometry, and internal friction or by step-by-step annealing using positron annihilation spectroscopy and hardness tests. Experimental results are explained by sequence of ordering transitions: A2 → D03 → L12.

18 CFR 2.1a - Public suggestions, comments, proposals on substantial prospective regulatory issues and problems.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Public suggestions, comments, proposals on substantial prospective regulatory issues and problems. 2.1a Section 2.1a Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL...

18 CFR 2.1a - Public suggestions, comments, proposals on substantial prospective regulatory issues and problems.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Public suggestions, comments, proposals on substantial prospective regulatory issues and problems. 2.1a Section 2.1a Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL...

18 CFR 2.1a - Public suggestions, comments, proposals on substantial prospective regulatory issues and problems.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Public suggestions, comments, proposals on substantial prospective regulatory issues and problems. 2.1a Section 2.1a Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL...

18 CFR 2.1a - Public suggestions, comments, proposals on substantial prospective regulatory issues and problems.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Public suggestions, comments, proposals on substantial prospective regulatory issues and problems. 2.1a Section 2.1a Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL...

Prevalence of prelingual deafness in Italy

PubMed Central

Bubbico, L; Rosano, A; Spagnolo, A

2007-01-01

Summary Neonatal hearing loss is the most frequent sensorial congenital defect in newborns. No data are available on worldwide prevalence of congenital deafness. World Health Organization (WHO) data indicate 1-4 cases per 1,000 individuals, with a considerable increase in developing countries. A prevalence exceeding 1 per 1,000 however, indicates a serious public health problem calling for urgent attention. Aim of the study was the evaluate the prevalence of prelingual deafness in the Italian population and determine the socio-demographic characteristics of the condition. Data were provided by the National Institute of Social Insurance (INPS) and the Italian Central Statistics Institute (ISTAT) and were collected in 18 out of the 20 Italian regions (98.2% of total population). All subjects recognized as deaf-mute by a special medical committee were included. According to law No. 509/1988, they had to present a mean bilateral sensorineural-hearing impairment, detected in neonatal age, which caused the damage in speech development and equal to 60 dB or more for 500-, 1,000- and 2,000-Hz frequency tones in the better ear. Prevalence rates were calculated according to region and age bracket using updated population data from census 2001. Statistical analyses were performed using the SPSS statistical software package. A total of 40,887 cases of prelingual profound sensorineural hearing loss ≥ 60 dB were detected in Italy in 2003, for a total prevalence rate of 0.72 per 1,000. The hearing impairment prevalence differs according to sex. The overall prevalence is 0.78 per 1,000 for males and 0.69 per 1,000 for females (p < 0.001). The hearing impairment prevalence differs according to region of residence (p < 0.001). The geographic distribution of prelingual deafness was found to be: North 15,644 cases (0.63 per 1,000), Central Italy 7,111 cases (0.64 per 1,000), South and Islands 18,132 (0.87 per 1,000). The prelingual hearing loss is highly prevalent in South Italy

A travelling standard for radiopharmaceutical production centres in Italy

NASA Astrophysics Data System (ADS)

Capogni, M.; de Felice, P.; Fazio, A.

Short-lived radionuclides, γ, β+ and/or β- emitters, such as 18F, and 99mTc, particularly useful for nuclear medicine applications, both diagnostic and in radiotherapy, can be produced with high-specific activity in a small biomedical cyclotron or by a radionuclide generator. While [18F]Fludeoxyglucose ([18F]FDG) is a widely used radiopharmaceutical for positron emission tomography, the development of innovative diagnostic techniques and therapies involves the use of new radio-labelled molecules and emerging radionuclides, such as 64Cu and 124I. During the last 3 years, an extensive supply of [18F]FDG was started by many production sites in Italy, and new radiopharmaceuticals are being studied for future nuclear medical applications. Therefore, a special nuclear medicine research programme for primary standard development and transferral to the end-users has been carried out by the ENEA-INMRI. Because of the short half-lives of these nuclides, a portable well-type ionisation chamber was established as a secondary travelling standard. This device has been calibrated and transported to the radiopharmaceutical production centres in Italy where the local instrumentation, typically radionuclide calibrators, has been calibrated by a simple comparison, with an uncertainty level lower than 2%.

Induced abortion and contraception in Italy.

PubMed

Spinelli, A; Grandolfo, M E

1991-09-01

This article discusses the legal and epidemiologic status of abortion in Italy, and its relationship to fertility and contraception. Enacted in May 1978, Italy's abortion law allows the operation to be performed during the 1st 90 days of gestation for a broad range of health, social, and psychological reasons. Women under 18 must receive written permission from a parent, guardian, or judge in order to undergo an abortion. The operation is free of charge. Health workers who object to abortion because of religious or moral reasons are exempt from participating. Regional differences exist concerning the availability of abortion, easy to procure in some places and difficult to obtain in others. After an initial increase following legalization, the abortion rate was 13.5/1000 women aged 15-44 and the abortion ratio was 309/1000 live births -- an intermediate rate and ratio compared to other countries. By the time the Abortion Act of 1978 was adopted, Italy already had one of the lowest fertility levels in Europe. Thus, the legalization of abortion has had no impact on fertility trends. Contrary to initial fears that the legalization of abortion would make abortion a method of family planning, 80% of the women who sought an abortion in 1983-88 were using birth control at the time (withdrawal being the most common method used by this group). In fact, most women who undergo abortions are married, between the ages of 25-34, and with at least one child. Evidence indicates widespread ignorance concerning reproduction. In a 1989 survey, only 65% of women could identify the fertile period of the menstrual cycle. Italy has no sex education in schools or national family planning programs. Compared to most of Europe, Italy still has low levels of reliable contraceptive usage. This points to the need to guarantee the availability of abortion.

Seasonal variations of NO and O3 at altitudes of 18.3 and 21.3 km

NASA Technical Reports Server (NTRS)

Loewenstein, M.; Savage, H. F.; Whitten, R. C.

1975-01-01

Nitric oxide and ozone concentrations have been measured in situ from a high-altitude research aircraft. Data which show the variations of NO and O3 with the time of year are presented for altitudes of 18.3 and 21.3 km. The extreme values of the observed NO concentrations at 21.3 km are 1.2 billion per cu cm in summer and 0.2 billion per cu cm in winter. At 18.3 km the extreme values are 1.6 billion per cu cm in summer and 0.1 billion per cu cm in winter. The smoothed NO seasonal data show a variation of about a factor of 2.5 at 21.3 km and a factor of 4 at 18.3 km. The ozone data show the generally expected magnitude and seasonal variation. We have used a photochemical model employing the measured ozone concentrations, the mean solar zenith angle, and seasonal HNO3 data reported by others to predict the seasonal NO variation at 20 km. The result is a summer-to-winter NO ratio of 2.5 which is in fair agreement with the observed ratios.

Venice, Italy

NASA Technical Reports Server (NTRS)

2002-01-01

Four hundred bridges cross the labyrinth of canals that form the 120 islands of Venice, situated in a saltwater lagoon between the mouths of the Po and Piave rivers in northeast Italy. All traffic in the city moves by boat. Venice is connected to the mainland, 4 kilometers (2.5 miles) away, by ferries as well as a causeway for road and rail traffic. The Grand Canal winds through the city for about 3 kilometers (about 2 miles), dividing it into two nearly equal sections. According to tradition, Venice was founded in 452, when the inhabitants of Aquileia, Padua, and several other northern Italian cities took refuge on the islands of the lagoon from the Teutonic tribes invading Italy at that time.

This image was acquired on December 9, 2001 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER will image Earth for the next 6 years to map and monitor the changing surface of our planet.

ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with critical information for surface mapping, and monitoring dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

Dr. Anne

[Survey on computerized immunization registries in Italy].

PubMed

Alfonsi, V; D'Ancona, F; Ciofi degli Atti, M L

2008-01-01

Computerized immunization registries are essential for conducting and monitoring vaccination programs. In fact, they enable to improve vaccine offering to target population, generating needed-immunization lists and assessing levels of vaccination coverage. In 2007, a national survey on immunization registries was conducted in Italy. In February 2007, all the 21 Regional Health Authorities (RHAs) completed and returned an ad hoc questionnaire. In June 2007, RHAs were further contacted by telephone in order to verify and update the information provided in questionnaires. In 9 Italian Regions (42.8%), vaccination registries are computerized in all Local Health Units (LHUs). In five of these Regions, all LHUs use the same software, while in the remaining four Regions, different softwares are in use. In six additional Regions (28.6%), only some LHUs use computerized immunization registries (range 61.5%-95%). In the remaining 6 Regions (28.6%), which are all in Southern Italy, there are no computerised immunization registries at all. In total, computerised immunization registries cover 126/180 Italian LHUs (70%); in 76/126 (60%) of these LUHs, immunization registries are linked with population registries. This survey shows the need to improve the implementation of computerised immunization registries in Italy, especially in Southern Regions.

Molecular and serological detection of tick-borne pathogens in donkeys (Equus asinus) in Italy.

PubMed

Veronesi, Fabrizia; Morganti, Giulia; Ravagnan, Silvia; Laus, Fulvio; Spaterna, Andrea; Diaferia, Manuela; Moretti, Annabella; Fioretti, Daniela Piergili; Capelli, Gioia

2014-10-10

Donkeys, owing to the frequent outdoor activity, are exposed to a high risk of infection with tick-borne pathogens. This work aimed to detect exposure to Theileria equi, Babesia caballi, Anaplasma phagocytophilum and Borrelia burgdorferi s.l. of donkeys reared in Central Italy. For this purpose 122 adult donkeys were selected within 11 herds and submitted to blood collection. IgG antibodies to T. equi, B. caballi, A. phagocytophilum and B. burgdorferi s.l. were detected by IFAT. Conventional PCRs targeting the genes MSP2 and the flagellin were used for the detection of A. phagocytophilum and B. burgdorferi s.l. respectively and a Real Time PCR Sybr Green was used to detect Babesia/Theileria spp…. The species identity was determined by amplicons sequencing. Forty eight (39.3%) and 58 (47.5%) animals tested positive for T. equi and B. caballi antibodies, respectively; nine animals (7.4%) were found positive for antibodies against A. phagocytophilum whereas negative results were obtained for B. burgdorferi s.l. Twenty-six (21.3%) animals showed antibodies for both T. equi and B. caballi. Twenty-three (18.8%) donkeys were positive to Babesia/Theileria spp. PCR assay. Out of 21 sequenced amplicons, 20 were identified as T. equi, belonging to three main groups designated A, B and D and one as B. caballi group A. Neither A. phagocytophilum nor B. burgdorferi PCR results were positive. The study showed a high exposure of donkeys to tick-borne pathogens and provides information on the genetic identity of the T. equi strains circulating in Central Italy. Copyright © 2014 Elsevier B.V. All rights reserved.

21 CFR 740.18 - Coal tar hair dyes posing a risk of cancer.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Coal tar hair dyes posing a risk of cancer. 740.18... posing a risk of cancer. (a) The principal display panel of the label and any labeling accompanying a... your skin and has been determined to cause cancer in laboratory animals. (b) Hair dyes containing any...

21 CFR 740.18 - Coal tar hair dyes posing a risk of cancer.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Coal tar hair dyes posing a risk of cancer. 740.18... posing a risk of cancer. (a) The principal display panel of the label and any labeling accompanying a... your skin and has been determined to cause cancer in laboratory animals. (b) Hair dyes containing any...

21 CFR 740.18 - Coal tar hair dyes posing a risk of cancer.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Coal tar hair dyes posing a risk of cancer. 740.18... posing a risk of cancer. (a) The principal display panel of the label and any labeling accompanying a... your skin and has been determined to cause cancer in laboratory animals. (b) Hair dyes containing any...

21 CFR 740.18 - Coal tar hair dyes posing a risk of cancer.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Coal tar hair dyes posing a risk of cancer. 740.18... posing a risk of cancer. (a) The principal display panel of the label and any labeling accompanying a... your skin and has been determined to cause cancer in laboratory animals. (b) Hair dyes containing any...

Autosomal Dominant Nonsyndromic Cleft Lip and Palate: Significant Evidence of Linkage at 18q21.1

PubMed Central

Beiraghi, Soraya ; Nath, Swapan K. ; Gaines, Matthew ; Mandhyan, Desh D. ; Hutchings, David ; Ratnamala, Uppala ; McElreavey, Ken ; Bartoloni, Lucia ; Antonarakis, Gregory S. ; Antonarakis, Stylianos E. ; Radhakrishna, Uppala 

2007-01-01

Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common congenital facial defects, with an incidence of 1 in 700–1,000 live births among individuals of European descent. Several linkage and association studies of NSCL/P have suggested numerous candidate genes and genomic regions. A genomewide linkage analysis of a large multigenerational family (UR410) with NSCL/P was performed using a single-nucleotide–polymorphism array. Nonparametric linkage (NPL) analysis provided significant evidence of linkage for marker rs728683 on chromosome 18q21.1 (NPL=43.33 and P=.000061; nonparametric LOD=3.97 and P=.00001). Parametric linkage analysis with a dominant mode of inheritance and reduced penetrance resulted in a maximum LOD score of 3.61 at position 47.4 Mb on chromosome 18q21.1. Haplotype analysis with informative crossovers defined a 5.7-Mb genomic region spanned by proximal marker rs1824683 (42,403,918 bp) and distal marker rs768206 (48,132,862 bp). Thus, a novel genomic region on 18q21.1 was identified that most likely harbors a high-risk variant for NSCL/P in this family; we propose to name this locus “OFC11” (orofacial cleft 11). PMID:17564975

Italy Country Analysis Brief

EIA Publications

2016-01-01

Italy is the fourth largest energy consumer in Europe, after Germany, France, and United Kingdom. Italy's primary energy consumption is driven by oil and gas, which contributed to over three-quarters of Italy's total consumption. The remaining portion is made up of coal, hydro, and other renewable energy sources. Renewable energy sources, excluding hydroelectricity, have increased their share in Italy's energy consumption from less than 2% in 2005 to nearly 10% in 2015. As a net importer of crude oil and natural gas, Italy is heavily dependent on imports to meet about 90% of its oil and gas needs and to maintain its exports of refined petroleum products.

Familial ring (18) mosaicism in a 23-year-old young adult with 46,XY,r(18) (::p11→q21::)/46,XY karyotype, intellectual disability, motor retardation and single maxillary incisor and in his phenotypically normal mother, karyotype 47,XX,+r(18)(::p11→q21::)/46,XX.

PubMed

Balci, Sevim; Tümer, Celal; Karaca, Ciğdem; Bartsch, Oliver

2011-05-01

We report on a 23-year-old man with craniofacial findings of the holoprosencephaly spectrum disorder (microcephaly, hypotelorism, depressed nasal bridge, single median maxillary central incisor), fusion of C2-C3 vertebrae, intellectual disability, and severe sleep apnea. Chromosome analysis of blood lymphocytes showed 75% ring (18) cells and 25% normal cells, karyotype mos 46,XY,r(18)(::p11→q21::)[75]/46,XY[25]. His mother was phenotypically normal except for a double ureter and bifid renal pelvis as in his son. She had a supernumerary ring (18) in 10% of blood lymphocytes, karyotype mos 47,XX,+r(18)(::p11→q21::)[10]/46,XX[90]. Familial ring (18) is a rare cytogenetic abnormality. This is the first report of a mother with a supernumerary ring (18) and a son with ring (18) mosaicism. Interestingly, the son showed a true mosaicism (mixoploidy) of ring (18) and normal cells. The mother's 46,XX cells could be easily explained by mitotic instability and ring loss during cell division. However, the coexistence of ring (18) and normal cells in the son is unusual. Possibly, during early postzygotic divisions of a 47,XY,+r(18) zygote, two (possibly subsequent) genetic events could have occurred, one when one normal chromosome 18 was lost (resulting in a cell line with ring 18), and one when the ring 18 was lost (resulting in a cell line without ring, "escape to normal"). Alternatively, the zygote of the son could have been 46,XY,r(18), and postzygotic loss of the ring 18 could have resulted in monosomy 18 cells followed by duplication of chromosome 18 in these cells (a rare mechanism for cell survival previously described as "compensatory" isodisomy). Copyright © 2011 Wiley-Liss, Inc.

Chapter 44: history of neurology in Italy.

PubMed

Bentivoglio, Marina; Mazzarello, Paolo

2010-01-01

The chapter starts from the Renaissance (although the origins of Italian neurology can be traced back to the Middle Ages), when treatises of nervous system physiopathology still followed Hippocratic and Galenic "humoral" theories. In Italy, as elsewhere in Europe, the concepts of humoral pathology were abandoned in the 18th century, when neurology was influenced by novel trends. Neurology acquired the status of clinical discipline (as "clinic of mental diseases") after national reunification (declared in 1861 but completed much later). At the end of the 19th and first decades of the 20th century, eminent Italian "neuropsychiatrists" (including, among many others, Ugo Cerletti, who introduced electroconvulsive shock therapy in 1938) stimulated novel knowledge and approaches, "centers of excellence" flourished, and "Neurological Institutes" were founded. In the first half of the 20th century, the history of Italian neurology was dominated by World Wars I and II (which stimulated studies on the wounded) and the fascist regime in-between the Wars (when the flow of information was instead very limited). Italy became a republic in 1946, and modern neurology and its distinction from psychiatry were finally promoted. The chapter also provides detailed accounts of scientific societies and journals dedicated to the neurological sciences in Italy.

Serological survey on Leptospira infection in slaughtered swine in North-Central Italy.

PubMed

Bertelloni, F; Turchi, B; Vattiata, E; Viola, P; Pardini, S; Cerri, D; Fratini, F

2018-05-30

Swine can act as asymptomatic carriers of some Leptospira serovars. In this study, 1194 sera from 61 farms located in five different Regions of North-West Italy were collected from slaughtered healthy pigs. Presence of antibody against four Leptospira serovars was evaluated. Overall, 52.5% of analysed farms presented at least one positive animal and 34.4% presented at least one positive swine with titre ⩾1:400. A percentage of 16.6% sera was positive and 5.9% samples presented a positive titre ⩾1:400. Tuscany and Lombardy showed the highest percentage of positive farms (64.3% and 54.6%, respectively) and sera (28.5% and 13.3%, respectively), probably due to environmental conditions and potential risk factors, which promote maintenance and spreading of Leptospira in these areas. The main represented serogroups were Australis (21.3% positive farms, 8.2% positive sera) and Pomona (18.0% positive farms, 8.1% positive sera). In swine, these serogroups are the most detected worldwide; however, our results seem to highlight a reemerging of serogroup Pomona in pigs in investigated areas. A low percentage of sera (0.6%) scored positive to Canicola, leaving an open question on the role of pigs in the epidemiology of this serovar. Higher antibody titres were detected for serogroups Australis and Pomona. Swine leptospirosis is probably underestimated in Italy and could represent a potential risk for animal and human health.

18 CFR 157.21 - Pre-filing procedures and review process for LNG terminal facilities and other natural gas...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Pre-filing procedures... applications. 157.21 Section 157.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY...) A description of a Public Participation Plan which identifies specific tools and actions to...

18 CFR 157.21 - Pre-filing procedures and review process for LNG terminal facilities and other natural gas...

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Pre-filing procedures... applications. 157.21 Section 157.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY...) A description of a Public Participation Plan which identifies specific tools and actions to...

18 CFR 157.21 - Pre-filing procedures and review process for LNG terminal facilities and other natural gas...

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Pre-filing procedures... applications. 157.21 Section 157.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY...) A description of a Public Participation Plan which identifies specific tools and actions to...

Chromosomal imbalances are associated with outcome of Helicobacter pylori eradication in t(11;18)(q21;q21) negative gastric mucosa-associated lymphoid tissue lymphomas.

PubMed

Fukuhara, Noriko; Nakamura, Tsuneya; Nakagawa, Masao; Tagawa, Hiroyuki; Takeuchi, Ichiro; Yatabe, Yasushi; Morishima, Yasuo; Nakamura, Shigeo; Seto, Masao

2007-08-01

Approximately 70% of gastric mucosa-associated lymphoid tissue (MALT) lymphomas can be successfully treated with H. pylori eradication. The translocation t(11;18)(q21;q21) characteristic of MALT lymphoma is recognized as a marker for H. pylori independency, but this marker is found in only a half of the MALT lymphomas resistant to H. pylori eradication. Detailed analyses of the genomic features of eradication resistant as well as responsive groups are important for understanding their molecular basis. We performed array-based comparative genomic hybridization (array-CGH) for 29 gastric MALT lymphomas treated with H. pylori eradication. These comprised ten cases of t(11;18) positive MALT, nine cases of t(11;18) negative MALT with H. pylori dependency, and ten cases of t(11;18) negative MALT with H. pylori independency. Array-CGH analysis demonstrated that no significant genetic alterations were found in t(11;18) positive MALT lymphomas, but numerous genomic alterations were detected in t(11;18) negative MALT lymphomas. Many of these alterations were similar to those found in diffuse large B-cell lymphoma with trisomy 3 being the most recurrent alteration. Within the t(11;18) negative MALT lymphoma without large cell components group, genomic imbalances occurred more frequently in the H. pylori independent than in the H. pylori dependent group (P = 0.02). Genomic imbalances are associated with H. pylori independency in t(11;18) negative gastric MALT lymphomas. They may thus play an important role in the development of H. pylori independency.

21st International Seapower Symposium

DTIC Science & Technology

2015-02-01

frequency ] radio on channel ten. • AV17-8 T2000: I intend to conduct vertical replenishment operations at 2000. • X Corpen Port 000: I intend to alter...welcome you to Newport, Rhode Island, for the 21st International Seapower Symposium (ISS-21). The International Naval Community is well-represented...Italy .......................... 173 Chapter 11 Closing Remarks Rear Admiral P. Gardener Howe III and Admiral Jonathan W. Greenert, U.S. Navy

Prevalence of previously undiagnosed abdominal aortic aneurysms in the area of Como: the ComoCuore "looking for AAA" ultrasonography screening.

PubMed

Corrado, Giovanni; Durante, Alessandro; Genchi, Vincenzo; Trabattoni, Loris; Beretta, Sandro; Rovelli, Enza; Foglia-Manzillo, Giovanni; Ferrari, Giovanni

2016-08-01

The prognosis for abdominal aortic aneurysm (AAA) rupture is poor. Long-term follow-up of population-based randomized trials has demonstrated that ultrasound (US) screening for abdominal aortic aneurysms (AAAs) measuring 3 cm or greater decreases AAA-related mortality rates and is cost-effective. We though to prospectively perform during a 26-month period a limited US examination of the infrarenal aorta in volunteers of both gender aged 60-85 years without history of AAA living in the area of Como, Italy. From September 2010 to November 2013 ComoCuore, a no-profit nongovernmental association, enrolled 1555 people (aged 68.8 ± 6.8 years; 48.6 % males). Clinical data and a US imaging of the aorta were collected for each participant. AAA was found in 22 volunteers (1.4 %) mainly males (2.5 % in males vs. 0.4 % in females p = 0.005). Overall, the prevalence of cardiovascular risk factors was higher in patients with vs. without AAA (mean 2.9 ± 3.0 vs. 1.4 ± 1.0 respectively, p < 0.0001). Independent predictors of AAA on multivariate analysis were age (OR 1.14, 1.06-1.22; p < 0.0001), male gender (OR 8.23, 1.79-37.91; p = 0.007), and both current (OR 4.98, 1.57-15.79; p = 0.007) and previous smoking (OR 2.76, 1.12-8.94; p = 0.03). Our study confirms the feasibility of one time US screening for AAA in a large cohort of asymptomatic people. Independent predictors of AAA were male sex, older age and a history of smoking. Accordingly to recent data the prevalence of AAA seems to be declining, maybe due to a reduction of smoking in Italy.

Preliminary study of plants used in ethnoveterinary medicine in Tunisia and in Italy.

PubMed

Viegi, Lucia; Ghedira, Kamel

2014-01-01

A survey relative to the use of plants for the cure of animals in Tunisia was conducted in order to make a comparison with the same species (or similar ones) in central and southern Italy. available bibliographical data both for Italy and for Tunisia were consulted. Thirty-nine plants, representing 22 families, used in Tunisia in ethnoveterinary medicine were reported, and comparisons made with close species used in Central and Southern Italy. Seven of the 39 species (about the 18% of the total) are not present in Italian flora. Fourteen of the 39 species (35% of the total) are also used in Italy. Camelidae (dromedaries and camels) are the most valuable types of domestic animals cured in Tunisia, but ovines, horses, bulls, dogs are also treated. Some uses coincide with those existing in different Italian regions. The plants used are the most common and most easily found in these areas. The present study confirms the convergence in ethnoveterinary medicine between Tunisia and Italy, even if it appears less significant than in human ethnobotany. Further studies are required in areas of Tunisia that have not yet been studied, in order to get the possibility of an evaluation of active compounds.

18 CFR 2.21 - Regional Transmission Groups.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Groups. 2.21 Section 2.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION... Interpretations Under the Federal Power Act § 2.21 Regional Transmission Groups. (a) General policy. The Commission encourages Regional Transmission Groups (RTGs) as a means of enabling the market for electric...

Spatial frequency-dependent feedback of visual cortical area 21a modulating functional orientation column maps in areas 17 and 18 of the cat.

PubMed

Huang, Luoxiu; Chen, Xin; Shou, Tiande

2004-02-20

The feedback effect of activity of area 21a on orientation maps of areas 17 and 18 was investigated in cats using intrinsic signal optical imaging. A spatial frequency-dependent decrease in response amplitude of orientation maps to grating stimuli was observed in areas 17 and 18 when area 21a was inactivated by local injection of GABA, or by a lesion induced by liquid nitrogen freezing. The decrease in response amplitude of orientation maps of areas 17 and 18 after the area 21a inactivation paralleled the normal response without the inactivation. Application in area 21a of bicuculline, a GABAa receptor antagonist caused an increase in response amplitude of orientation maps of area 17. The results indicate a positive feedback from high-order visual cortical area 21a to lower-order areas underlying a spatial frequency-dependent mechanism.

Computational Methods for Predictive Simulation of Stochastic Turbulence Systems

DTIC Science & Technology

2015-11-05

Science and Engineering, Venice , Italy, May 18-20, 2015, pp. 1261-1272. [21] Yong Li and P.D. Williams Analysis of the RAW Filter in Composite-Tendency...leapfrog scheme, Proceedings of the VI Conference on Computational Methods for Coupled Problems in Science and Engineering, Venice , Italy, May 18-20

Evidence for bovine besnoitiosis being endemic in Italy--first in vitro isolation of Besnoitia besnoiti from cattle born in Italy.

PubMed

Gentile, A; Militerno, G; Schares, G; Nanni, A; Testoni, S; Bassi, P; Gollnick, N S

2012-03-23

Until 2009, bovine besnoitiosis had never been considered endemic in Italy and the only report on the disease in this country referred to animals imported from France shortly before. However, recently, an autochthonous outbreak of bovine besnoitiosis was reported in four herds located at the intersection of the borders between Emilia-Romagna, Toscana and Marche (Northern Apennine Mountains), which has led to an increased awareness concerning this disease. The present study describes a further outbreak of bovine besnoitiosis in Italy. The afflicted herd was a dairy herd with no evidence for contact with cattle from regions known to be endemic for bovine besnoitiosis. The farm investigation was initiated after a three-year old Holstein Friesian dairy cow with generalized thickening and lichenification of the skin was diagnosed with bovine besnoitiosis. The clinical diagnosis was confirmed by gross pathology, histopathology, serology and PCR. Bradyzoites released from tissue cysts obtained from the skin of this animal enabled the first in vitro isolation of Besnoitia besnoiti in Italy. This isolate was named Bb-Italy1. Sequencing of a 2118 bp spanning region including the complete internal transcribed spacer 1 and parts of the 18S and the 5.8S rRNA gene from DNA extracted from skin-derived zoites revealed a 99.9% identity to sequences known for other B. besnoiti isolated from cattle in Europe. Two GKO mice which had been inoculated intraperitoneally with bovine skin-derived bradyzoites became ill 7 days post inoculation. Parasitophorous vacuoles with multiplying zoites were observed in the cell culture inoculated with peritoneal fluids of these mice and a B. besnoiti infection in the mice and in the cell culture could be confirmed by real-time PCR. A serological investigation in the afflicted herd using immunoblots and an immunofluorescent antibody test (IFAT) revealed an overall herd seroprevalence of 9.7% (31/321), whereas within the female animals older than 2

Mdm-2 binding and TAF(II)31 recruitment is regulated by hydrogen bond disruption between the p53 residues Thr18 and Asp21.

PubMed

Jabbur, James R; Tabor, Amy D; Cheng, Xiaodong; Wang, Hua; Uesugi, Motonari; Lozano, Guillermina; Zhang, Wei

2002-10-10

Analyses of five wild-type p53 containing cell lines revealed lineage specific differences in phosphorylation of Thr18 after treatment with ionizing (IR) or ultraviolet (UV) radiation. Importantly, Thr18 phosphorylation correlated with induction of the p53 downstream targets p21(Waf1/Cip1) (p21) and Mdm-2, suggesting a transactivation enhancing role. Thr18 phosphorylation has been shown to abolish side-chain hydrogen bonding between Thr18 and Asp21, an interaction necessary for stabilizing alpha-helical conformation within the transactivation domain. Mutagenesis-derived hydrogen bond disruption attenuated the interaction of p53 with the transactivation repressor Mdm-2 but had no direct effect on the interaction of p53 with the basal transcription factor TAF(II)31. However, prior incubation of p53 mutants with Mdm-2 modulated TAF(II)31 interaction with p53, suggesting Mdm-2 blocks the accessibility of p53 to TAF(II)31. Consistently, p53-null cells transfected with hydrogen bond disrupting p53 mutants demonstrated enhanced endogenous p21 expression, whereas p53/Mdm-2-double null cells exhibited no discernible differences in p21 expression. We conclude disruption of intramolecular hydrogen bonding between Thr18 and Asp21 enhances p53 transactivation by modulating Mdm-2 binding, facilitating TAF(II)31 recruitment.

Early pregnancy diagnosis on days 18 to 21 postinsemination using high-resolution imaging in lactating dairy cows.

PubMed

Scully, S; Butler, S T; Kelly, A K; Evans, A C O; Lonergan, P; Crowe, M A

2014-01-01

The aim was to assess the ability of corpus luteum (CL) and uterine ultrasound characteristics on d 18 to 21 to predict pregnancy status in lactating dairy cows. Ultrasound examinations were carried out on cows (n = 164) on d 18 to 21 following artificial insemination (AI). Images of the uterus and CL were captured using a Voluson i ultrasound device (General Electric Healthcare Systems, Vienna, Austria) equipped with a 12-MHz, multi frequency, linear array probe. Serum concentrations of progesterone were determined from blood samples collected at each ultrasound examination. Images of the CL were captured and stored for calculation of CL tissue area and echotexture. Images of the CL and associated blood flow area were captured and stored for analysis of luteal blood flow ratio. Longitudinal B-mode images of the uterine horns were stored for analysis of echotexture. Diagnosis of pregnancy was made at each ultrasound examination based on CL blood flow, CL size, and uterine echotexture. Pregnancy was confirmed by ultrasonography on d 30 after AI. The relationship between ultrasound measures and pregnancy outcome, as well as the accuracy of the pregnancy diagnosis made at each ultrasound examination was assessed. Progesterone concentrations and CL tissue area were greater in pregnant compared with nonpregnant cows on all days. The CL blood flow ratio was higher in pregnant compared with nonpregnant cows on d 20 and 21 after AI. Echotexture measures of the CL and uterus were not different between pregnant and nonpregnant cows on any day of examination. The best logistic regression model to predict pregnancy included scores for CL blood flow, CL size, and uterine echotexture on d 21 following AI. Accuracy of pregnancy diagnosis was highest on d 21, with sensitivity and specificity being 97.6 and 97.5%, respectively. Uterine echotexture scores were similar for pregnant and nonpregnant cows from d 18 to 20. On d 21, pregnant cows had higher uterine echotexture scores

Helicobacter pylori and the t(11;18)(q21;q21) translocation in gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type.

PubMed

Nakamura, T; Nakamura, S; Yonezumi, M; Suzuki, T; Matsuura, A; Yatabe, Y; Yokoi, T; Ohashi, K; Seto, M

2000-03-01

The reported regression of mucosa-associated lymphoid tissue (MALT) type gastric low-grade B-cell lymphoma following treatment for Helicobacter pylori (H. pylori) infection has not yet been comprehensively analyzed, especially in relation to the recently identified c-IAP2-MALT1 / MLT gene alteration resulting from the t(11;18)(q21;q21) chromosomal translocation found in MALT lymphoma. The relationship between MALT lymphomas and H. pylori was investigated in 30 patients who received an antibacterial treatment. Patients were followed up by means of endoscopy and biopsy. Molecular genetic analyses focused on the presence or absence of the immunoglobulin heavy chain (IgH) gene and / or MALT1 / MLT gene alteration resulting from t(11;18)(q21;q21) translocation. H. pylori was positive in 26 of the 30 patients. The overall success rate of cure of H. pylori infection was 96% (25 / 26). Thirteen patients (52%) showed complete remission (CR) of lymphoma, nine (36%) partial remission (PR), and three (12%) registered no change (NC). Statistical analysis revealed significant differences between CR and PR / NC patients in age ( < 60 or 60), in lymphoma location (single or multiple sites) and in the presence or absence of gene rearrangement before eradication (P < 0.05). Endoscopy showed a cobblestone appearance only in PR cases and polypoid features predominantly in NC cases. Two NC patients with polypoid gross appearance showed rearrangements involving either c-IAP2 or MALT1 gene in Southern blot analysis, while none of seven other resected patients with non-polypoid superficial gross appearance showed rearrangement. Gastric MALT lymphoma could be pragmatically subdivided into three groups, CR (MALT-A), PR (MALT-B), and NC (MALT-C) on the basis of the reaction to eradication of H. pylori. We speculate that MALT-A may represent an incipient neoplasm or dysplasia, MALT-B a neoplasm activated by antigenic stimulation of H. pylori, and MALT-C a lymphoma independent of H. pylori

Synthesis of 18,19-dihydroxycorticosterone.

PubMed

Harnik, M; Carmely, S; Cojocaru, M; Kashman, Y

1986-01-01

A four-step synthesis of 18,19-dihydroxycorticosterone 5c, starting with 19,21-dihydroxy-3,20-dioxopregn-5-ene-18,11 beta-lactone-di-(ethylene ketal) 2, is presented. Reduction of 2 with sodium aluminum bis-(methoxyethoxy)hydride gave 11 beta,18,19,21-tetrahydroxy-pregn-5-ene-3,20-dione-di-(ethylene ketal) 3a. Acetylation furnished the corresponding 18,19,21-triacetate 3b, which on treatment with a mixture of perchloric and acetic acids gave 18,19-dihydroxycorticosterone 18,19,21-triacetate 4b. Mild saponification yielded the title compound which, on the basis of ir and nmr spectra, exists as one C-20 isomer of the hemiacetal structure 5c. Periodate oxidation of 5c gave the expected 11 beta, 19-dihydroxy-3-oxoandrost-4-ene-17 beta, 18-carbolactone 6b.

Culture and the environment in Italy

NASA Astrophysics Data System (ADS)

Alexander, David

1985-03-01

This essay evaluates the historical development and current background of human-environment relationships in Italy. The Italian landscape consists of very varied terrain, and periodically suffers from all kinds of natural hazard, especially earthquakes, landslides, floods, and accelerated soil erosion. Some measure of environmental conservation was achieved by the Etruscans and Romans, but the Classical period also marked the beginning of serious lowland waterlogging, malarial infestation, upland soil erosion, and deforestation, which all increased during the Middle Ages. From the Renaissance to the 18th century, there was a diffusion of planned landscapes and carefully managed estates; but by the 20th century, many rural areas could not support growing populations and much land was in need of improvement. Underdevelopment and latifundium agriculture increased the vulnerability to environmental hazards of the Mezzogiorno (Italian South), while the subsequent disappearance of the peasant culture seems not to have led to greatly improved conservation or land management. Poorly farmed or managed landscapes and poorly maintained historic towns have undergone some virtually irreversible degradation, especially with respect to landslides and earthquake damage. Elsewhere in Italy, unchecked urbanization, weak planning laws, and their inadequate enforcement have helped both to reduce environmental quality, by overdevelopment of valued landscapes, and to increase natural disaster vulnerability, by encouraging occupance of natural hazard zones. Although there are signs that the government is beginning to respond to the cumulative effect of environmental degradation, the measures are insufficient to reverse the overall trend toward decadence that characterizes human-land relationships in Italy.

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 1 2014-04-01 2014-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 1 2012-04-01 2012-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 1 2013-04-01 2013-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 1 2011-04-01 2011-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

Synthesis of 3,4-dihydro-1,8-naphthyridin-2(1H)-ones via microwave-activated inverse electron-demand Diels-Alder reactions.

PubMed

Fadel, Salah; Hajbi, Youssef; Khouili, Mostafa; Lazar, Said; Suzenet, Franck; Guillaumet, Gérald

2014-01-01

Substituted 3,4-dihydro-1,8-naphthyridin-2(1H)-ones have been synthesized with the inverse electron-demand Diels-Alder reaction from 1,2,4-triazines bearing an acylamino group with a terminal alkyne side chain. Alkynes were first subjected to the Sonogashira cross-coupling reaction with aryl halides, the product of which then underwent an intramolecular inverse electron-demand Diels-Alder reaction to yield 5-aryl-3,4-dihydro-1,8-naphthyridin-2(1H)-ones by an efficient synthetic route.

18 CFR 12.21 - Exemptions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... from the requirements of § 12.22(c) for a radiological response plan. (c) Conditions of exemptions. (1... Section 12.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS AND PROJECT WORKS...

18 CFR 12.21 - Exemptions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... from the requirements of § 12.22(c) for a radiological response plan. (c) Conditions of exemptions. (1... Section 12.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS AND PROJECT WORKS...

18 CFR 12.21 - Exemptions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... from the requirements of § 12.22(c) for a radiological response plan. (c) Conditions of exemptions. (1... Section 12.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS AND PROJECT WORKS...

18 CFR 12.21 - Exemptions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... from the requirements of § 12.22(c) for a radiological response plan. (c) Conditions of exemptions. (1... Section 12.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS AND PROJECT WORKS...

18 CFR 4.21 - Reports.

Code of Federal Regulations, 2014 CFR

2014-04-01

... PROJECT COSTS Determination of Cost of Constructed Projects not Subject to Section 23(a) of the Act § 4.21 Reports. Representatives of the Commission will inspect the project works, engineering reports, and other records of the project, check the inventory and estimated depreciation, make an audit of the books...

18 CFR 4.21 - Reports.

Code of Federal Regulations, 2011 CFR

2011-04-01

... PROJECT COSTS Determination of Cost of Constructed Projects not Subject to Section 23(a) of the Act § 4.21 Reports. Representatives of the Commission will inspect the project works, engineering reports, and other records of the project, check the inventory and estimated depreciation, make an audit of the books...

Synthesis of 3,4-dihydro-1,8-naphthyridin-2(1H)-ones via microwave-activated inverse electron-demand Diels–Alder reactions

PubMed Central

Fadel, Salah; Hajbi, Youssef; Khouili, Mostafa; Lazar, Said

2014-01-01

Summary Substituted 3,4-dihydro-1,8-naphthyridin-2(1H)-ones have been synthesized with the inverse electron-demand Diels–Alder reaction from 1,2,4-triazines bearing an acylamino group with a terminal alkyne side chain. Alkynes were first subjected to the Sonogashira cross-coupling reaction with aryl halides, the product of which then underwent an intramolecular inverse electron-demand Diels–Alder reaction to yield 5-aryl-3,4-dihydro-1,8-naphthyridin-2(1H)-ones by an efficient synthetic route. PMID:24605148

18 CFR 153.21 - Conformity with requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Energy Projects may reject the application within 10 days of filing as provided by § 385.2001(b) of this... requirements. 153.21 Section 153.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER NATURAL GAS ACT APPLICATIONS FOR AUTHORIZATION TO...

18 CFR 153.21 - Conformity with requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Energy Projects may reject the application within 10 days of filing as provided by § 385.2001(b) of this... requirements. 153.21 Section 153.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER NATURAL GAS ACT APPLICATIONS FOR AUTHORIZATION TO...

18 CFR 153.21 - Conformity with requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Energy Projects may reject the application within 10 days of filing as provided by § 385.2001(b) of this... requirements. 153.21 Section 153.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER NATURAL GAS ACT APPLICATIONS FOR AUTHORIZATION TO...

18 CFR 35.21 - Applicability to licensees and others subject to section 19 or 20 of the Federal Power Act.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Applicability to licensees and others subject to section 19 or 20 of the Federal Power Act. 35.21 Section 35.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS...

5-Gb/s 0.18-μm CMOS 2:1 multiplexer with integrated clock extraction

NASA Astrophysics Data System (ADS)

Changchun, Zhang; Zhigong, Wang; Si, Shi; Peng, Miao; Ling, Tian

2009-09-01

A 5-Gb/s 2:1 MUX (multiplexer) with an on-chip integrated clock extraction circuit which possesses the function of automatic phase alignment (APA), has been designed and fabricated in SMIC's 0.18 μm CMOS technology. The chip area is 670 × 780 μm2. At a single supply voltage of 1.8 V, the total power consumption is 112 mW with an input sensitivity of less than 50 mV and an output single-ended swing of above 300 mV. The measurement results show that the IC can work reliably at any input data rate between 1.8 and 2.6 Gb/s with no need for external components, reference clock, or phase alignment between data and clock. It can be used in a parallel optic-fiber data interconnecting system.

Text neck and neck pain in 18-21-year-old young adults.

PubMed

Damasceno, Gerson Moreira; Ferreira, Arthur Sá; Nogueira, Leandro Alberto Calazans; Reis, Felipe José Jandre; Andrade, Igor Caio Santana; Meziat-Filho, Ney

2018-06-01

The aim of this study was to investigate whether there is an association between text neck and neck pain in young adults. Observational cross-sectional study with 150 18-21-year-old young adults from a public high school in the state of Rio de Janeiro was performed. In the self-report questionnaire, the participants answered questions on sociodemographic factors, anthropometric factors, time spent texting or playing on a mobile phone, visual impairments, and concern with the body posture. The neck posture was assessed by participants' self-perception and physiotherapists' judgment during a mobile phone texting message task. The Young Spine Questionnaire was used to evaluate the neck pain. Four multivariate logistic regression models were fitted to investigate the association between neck posture during mobile phone texting and neck pain, considering potential confounding factors. There is no association between neck posture, assessed by self-perception, and neck pain (OR = 1.66, p = 0.29), nor between neck posture, assessed by physiotherapists' judgment, and neck pain (OR = 1.23, p = 0.61). There was also no association between neck posture, assessed by self-perception, and frequency of neck pain (OR = 2.19, p = 0.09), nor between neck posture, assessed by physiotherapists' judgment, and frequency of neck pain (OR = 1.17, p = 0.68). This study did not show an association between text neck and neck pain in 18-21-year-old young adults. The findings challenge the belief that neck posture during mobile phone texting is associated to the growing prevalence of neck pain.

Replacing the combined test by cell-free DNA testing in screening for trisomies 21, 18 and 13: impact on the diagnosis of other chromosomal abnormalities.

PubMed

Syngelaki, Argyro; Pergament, Eugene; Homfray, Tessa; Akolekar, Ranjit; Nicolaides, Kypros H

2014-01-01

To estimate the proportion of other chromosomal abnormalities that could be missed if combined testing was replaced by cell-free (cf) DNA testing as the method of screening for trisomies 21, 18 and 13. The prevalence of trisomies 21, 18 or 13, sex chromosome aneuploidies, triploidy and other chromosomal abnormalities was examined in pregnancies undergoing first-trimester combined screening and chorionic villus sampling (CVS). In 1,831 clinically significant chromosomal abnormalities in pregnancies with combined risk for trisomies 21, 18 and 13≥1:100, the contribution of trisomies 21, 18 or 13, sex chromosome aneuploidies, triploidy and other chromosomal abnormalities at high risk of adverse outcome was 82.9, 8.2, 3.9 and 5.0%, respectively. Combined screening followed by CVS for risk≥1:10 and cfDNA testing for risk 1:11-1:2,500 could detect 97% of trisomy 21 and 98% of trisomies 18 and 13. Additionally, 86% of monosomy X, half of 47,XXY, 47,XYY or 47,XXX, half of other chromosomal abnormalities and one third of triploidies, which are currently detected by combined screening and CVS for risk≥1:100, could be detected. Screening by cfDNA testing, contingent on results of combined testing, improves detection of trisomies, but misses a few of the other chromosomal abnormalities detected by screening with the combined test. © 2014 S. Karger AG, Basel.

Impariamo Insieme in Italia (Learning Together in Italy) via "Scambio Di Instruzione--Through Instructional Exchange"

ERIC Educational Resources Information Center

Veltri, Barbara Torre

2015-01-01

Preparing teacher candidates for their roles in 21st century schools calls for direct experiences with inquisitive, linguistically diverse, and often technologically savvy students across global and economic contexts. This article presents the lessons learned from a practicum experience during a semester abroad in Italy, where faculty, teacher…

Patterns of adjuvant chemotherapy for stage II and III colon cancer in France and Italy.

PubMed

Bouvier, Anne-Marie; Minicozzi, Pamela; Grosclaude, Pascale; Bouvier, Véronique; Faivre, Jean; Sant, Milena

2013-08-01

European guidelines recommend adjuvant chemotherapy for stage III colon cancer but not for stage II. To determine the extent to which adjuvant chemotherapy was used in Italy and France. A common retrospective database of 2186 colon cancers diagnosed between 2003 and 2005 was analysed according to age, stage and presenting features. 38.9% of patients with stage II and 64.6% with stage III received chemotherapy in Italy, 21.7% and 65.1% in France. For stage II, the association between country and chemotherapy was only significant in patients diagnosed out of emergency (ORItaly/France: 3.05 [2.12-4.37], p<0.001) whereas patients diagnosed in emergency were as likely to receive chemotherapy in both countries. For stage III, there was a trend to a higher administration of chemotherapy for elderly patients in France compared to Italy. French patients were more likely than Italian to receive chemotherapy (OR: 1.91[1.32-2.78], p=0.001). Chemotherapy for stage III colon cancer was as extensively used in Italy as in France for young patients. Its administration could be increased in patients over 75. Stage II patients with a lower risk of relapse received chemotherapy more often in Italy than in France. Copyright © 2013 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Synthesis, crystal structures, and physical properties of the new Zintl phases A{sub 21}Zn{sub 4}Pn{sub 18} (A=Ca, Eu; Pn=As, Sb)—Versatile arrangements of [ZnPn{sub 4}] tetrahedra

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suen, Nian-Tzu; Wang, Yi; Bobev, Svilen, E-mail: bobev@udel.edu

Four new Zintl phases, Ca{sub 21}Zn{sub 4}As{sub 18}, Ca{sub 21}Zn{sub 4}Sb{sub 18}, Eu{sub 21}Zn{sub 4}As{sub 18} and Eu{sub 21}Zn{sub 4}Sb{sub 18} have been synthesized by metal flux reactions. Their structures have been established from single-crystal X-ray diffraction. Despite the similar chemical makeup and the identical formulae, the structures of the four compounds are not the same—Ca{sub 21}Zn{sub 4}As{sub 18}, Ca{sub 21}Zn{sub 4}Sb{sub 18} and Eu{sub 21}Zn{sub 4}As{sub 18} crystallize in the monoclinic space group C2/m (No. 12, Z=4) with the β-Ca{sub 21}Mn{sub 4}Sb{sub 18} structure type, while Eu{sub 21}Zn{sub 4}Sb{sub 18} adopts the Ba{sub 21}Cd{sub 4}Sb{sub 18} structure type withmore » the orthorhombic space group Cmce (No. 64, Z=8). Both structures are based on ZnAs{sub 4} or ZnSb{sub 4} tetrahedra, linked in slightly different ways, and Ca{sup 2+} and Eu{sup 2+} cations that fill the space between them. The structural relationships between the title compounds and other known ternary phases with intricate structures are discussed. Electrical resistivity measurement on single-crystalline Eu{sub 21}Zn{sub 4}Sb{sub 18} suggests an intrinsic semiconductor behavior with a band gap of ca. 0.2 eV. The temperature dependent DC magnetization measurement on the same material indicates Curie–Weiss paramagnetism in the high-temperature regime, and a spontaneous antiferromagnetic ordering below 8 K. The calculated effective moments of Eu confirm the divalent Eu{sup 2+} ground state, as expected from the Zintl–Klemm concept. - Graphical abstract: The four new Zintl phases—Ca{sub 21}Zn{sub 4}As{sub 18}, Ca{sub 21}Zn{sub 4}Sb{sub 18}, Eu{sub 21}Zn{sub 4}As{sub 18}, and Eu{sub 21}Zn{sub 4}Sb{sub 18}—crystallize in two structure types, showing the versatility in the arrangements of ZnAs{sub 4} and ZnSb{sub 4} tetrahedra. - Highlights: • Ca{sub 21}Zn{sub 4}As{sub 18}, Ca{sub 21}Zn{sub 4}Sb{sub 18}, Eu{sub 21}Zn{sub 4}As{sub 18}, and Eu{sub 21}Zn{sub 4}Sb

Incidence of rheumatoid arthritis, psoriatic arthritis and polymyalgia rheumatica in an inland area of central Italy: results of the CAMPO-RHE study.

PubMed

De Socio, Antonia; Perrotta, Fabio Massimo; Grasso, Guido Maria; Lubrano, Ennio

2018-01-01

The aim of the CAMPO-RHE study was to determine the incidence of rheumatoid arthritis (RA), psoriatic arthritis (PsA) and polymyalgia rheumatica (PMR) in patients attending a rheumatologic outpatient's clinic of a new institution in Campobasso, Italy. Campobasso is a small town of approximately 50,000 inhabitants located in the inland territory of central Italy (Molise), and Public Health is managed from a single health authority. In Italy, all citizens are registered with a National Health System of General Practitioner (GP) Physicians. Between the 1 st of June 2014 and the 31 st of May 2016, all consecutive adult patients, sent by a GP, of Campobasso with any diagnosis of musculoskeletal symptoms/signs/complaints were evaluated in a single rheumatology outpatient clinic of our Academic Unit. The clinic represents the first and unique reference for GPs about rheumatic diseases in the territory. Subjects were classified using the 2010 EULAR criteria for RA, the CASPAR criteria for PsA and the 2012 ACR classification criteria for PMR. 1003 adult patients, sent by GPs, with articular or musculoskeletal complaints visited our clinic. Of these, 409 inhabitants of the municipality of Campobasso were evaluated for the study. During the 2-year study period we diagnosed 18, 19 and 12 new cases of RA, PsA and PMR respectively, with a new incident cases rate of 21.4, 22.59 and 27.43/100,000/year on the population at risk. The results of our study could contribute to better define the incidence of these rheumatic diseases classified with the new classification criteria.

Volatile components of horsetail (Hippuris vulgaris L.) growing in central Italy.

PubMed

Cianfaglione, Kevin; Papa, Fabrizio; Maggi, Filippo

2017-10-01

Hippuris vulgaris, also known as horsetail or marestail, is a freshwater macrophyte occurring in lakes, rivers, ponds and marshes. According to 'The IUCN Red List of Threatened Species', H. vulgaris is at a high risk of extinction in Italy in the medium-term future. In the present study, we analysed for the first time the volatile composition of H. vulgaris growing in central Italy. For the purpose, the essential oil was obtained by hydrodistillation and analysed by GC-MS. The chemical composition was dominated by aliphatic compounds such as fatty acids (26.0%), ketones (18.7%) and alkanes (11.4%), whereas terpenoids were poorer and mostly represented by diterpenes (7.4%). n-Hexadecanoic acid (25.5%), hexahydrofarnesyl acetone (17.5%) and trans-phytol (7.4%) were the major volatile constituents. These compounds are here proposed as chemotaxonomic markers of the species.

The 18Ne(α,p)21Na breakout reaction in x-ray bursts: Experimental determination of spin-parities for α resonances in 22Mg via resonant elastic scattering of 21Na+p

NASA Astrophysics Data System (ADS)

He, J. J.; Zhang, L. Y.; Parikh, A.; Xu, S. W.; Yamaguchi, H.; Kahl, D.; Kubono, S.; Hu, J.; Ma, P.; Chen, S. Z.; Wakabayashi, Y.; Sun, B. H.; Wang, H. W.; Tian, W. D.; Chen, R. F.; Guo, B.; Hashimoto, T.; Togano, Y.; Hayakawa, S.; Teranishi, T.; Iwasa, N.; Yamada, T.; Komatsubara, T.

2013-07-01

The 18Ne(α,p)21Na reaction provides a pathway for breakout from the hot CNO cycles to the rp process in type-I x-ray bursts. To better determine this astrophysical reaction rate, the resonance parameters of the compound nucleus 22Mg have been investigated by measuring the resonant elastic scattering of 21Na+p. An 89 MeV 21Na radioactive ion beam was produced at the CNS Radioactive Ion Beam Separator and bombarded an 8.8 mg/cm2 thick polyethylene target. The recoiled protons were measured at scattering angles of θc.m.≈175∘ and 152∘ by three ΔE-E silicon telescopes. The excitation function was obtained with a thick-target method over energies Ex(22Mg) = 5.5-9.2 MeV. The resonance parameters have been determined through an R-matrix analysis. For the first time, the Jπ values for ten states above the α threshold in 22Mg have been experimentally determined in a single consistent measurement. We have made three new Jπ assignments and confirmed seven of the ten tentative assignments in the previous work. The 18Ne(α,p)21Na reaction rate has been recalculated, and the astrophysical impact of our new rate has been investigated through one-zone postprocessing x-ray burst calculations. We find that the 18Ne(α,p)21Na rate significantly affects the peak nuclear energy generation rate and the onset temperature of this breakout reaction in these phenomena.

Estimates of cancer deaths attributable to behavioural risk factors in Italy, 2013.

PubMed

Battisti, Francesca; Carreras, Giulia; Grassi, Tommaso; Chellini, Elisabetta; Gorini, Giuseppe

2017-01-01

"Non-communicable diseases cause more than 80% of deaths in europe and, among these, 20% are caused by cancer. Modifiable lifestyle factors considered in the italian national programme "Guadagnare salute" (Gaining health), such as tobacco smoking, unhealthy diet, physical inactivity, overweight, and excessive alcohol use, are amongst the major causes of cancer deaths. The aims of this study was to estimate the number of deaths attributable to lifestyle factors for italy and for italian regions in 2013 and to describe its variation in relation to the regional prevalence of risk factors exposure. For Italy and for each italian region, deaths attributable to lifestyle factors were estimated using the methodology of the Global Burden of disease (GBd) study. italian mortality data of 2013 and risks attributable to these lifestyle factors for each cancer site for italy from the GBd study were used. Prevalence of exposure to lifestyles in Italy and in each Italian Region was collected for the period 2008-2013. In 2013, at least 66,605 cancer deaths in italy were attributable to lifestyle factors, accounting for 37.9% of all cancer deaths: 34.1% of cancer deaths in men and 9.0% in women were attributable to smoking; in men and women, respectively, 3.3% and 2.8% were attributable to excessive alcohol consumption; 5.3 % and 6.7% to overweight; 10.1% and 7.1% to dietary risk factors; 1.9% and 4.2% to physical inactivity. A moderate variability of percentage of deaths attributable to modifi able lifestyle factors by region was also detected due to different prevalence values of exposure to lifestyles occurred in last decades. At least 45,000 cancer deaths in men and 21,000 in women occurred in 2013 were attributable to modifi able risk factors, whose prevalence varied by region and which could be averted through the implementation of primary prevention interventions."

Noninvasive prenatal screening for fetal trisomies 21, 18, 13 and the common sex chromosome aneuploidies from maternal blood using massively parallel genomic sequencing of DNA.

PubMed

Porreco, Richard P; Garite, Thomas J; Maurel, Kimberly; Marusiak, Barbara; Ehrich, Mathias; van den Boom, Dirk; Deciu, Cosmin; Bombard, Allan

2014-10-01

The objective of this study was to validate the clinical performance of massively parallel genomic sequencing of cell-free deoxyribonucleic acid contained in specimens from pregnant women at high risk for fetal aneuploidy to test fetuses for trisomies 21, 18, and 13; fetal sex; and the common sex chromosome aneuploidies (45, X; 47, XXX; 47, XXY; 47, XYY). This was a prospective multicenter observational study of pregnant women at high risk for fetal aneuploidy who had made the decision to pursue invasive testing for prenatal diagnosis. Massively parallel single-read multiplexed sequencing of cell-free deoxyribonucleic acid was performed in maternal blood for aneuploidy detection. Data analysis was completed using sequence reads unique to the chromosomes of interest. A total of 3430 patients were analyzed for demographic characteristics and medical history. There were 137 fetuses with trisomy 21, 39 with trisomy 18, and 16 with trisomy 13 for a prevalence rate of the common autosomal trisomies of 5.8%. There were no false-negative results for trisomy 21, 3 for trisomy 18, and 2 for trisomy 13; all 3 false-positive results were for trisomy 21. The positive predictive values for trisomies 18 and 13 were 100% and 97.9% for trisomy 21. A total of 8.6% of the pregnancies were 21 weeks or beyond; there were no aneuploid fetuses in this group. All 15 of the common sex chromosome aneuploidies in this population were identified, although there were 11 false-positive results for 45,X. Taken together, the positive predictive value for the sex chromosome aneuploidies was 48.4% and the negative predictive value was 100%. Our prospective study demonstrates that noninvasive prenatal analysis of cell-free deoxyribonucleic acid from maternal plasma is an accurate advanced screening test with extremely high sensitivity and specificity for trisomy 21 (>99%) but with less sensitivity for trisomies 18 and 13. Despite high sensitivity, there was modest positive predictive value for the

Gypsum karst in Italy: a review

NASA Astrophysics Data System (ADS)

De Waele, Jo; Chiarini, Veronica; Columbu, Andrea; D'Angeli, Ilenia M.; Madonia, Giuliana; Parise, Mario; Piccini, Leonardo; Vattano, Marco; Vigna, Bartolomeo; Zini, Luca; Forti, Paolo

2016-04-01

Although outcropping only rarely in Italy, gypsum karst has been described in detail since the early XXth century (Marinelli, 1917). Gypsum caves are now known from almost all Italian regions (Madonia & Forti, 2003), but are mainly localised along the northern border of the Apennine chain (Emilia Romagna and Marche regions), Calabria, and Sicily, where the major outcrops occur. Recently, important caves have also been discovered in the underground gypsum quarries in Piedmont (Vigna et al., 2010). During the late 80s and 90s several multidisciplinary studies have been carried out in many gypsum areas. All this work converged into a comprehensive overview in 2003 (Madonia & Forti, 2003). Further detailed studies focused on the gypsum areas of Emilia Romagna (Chiesi et al., 2010; Forti & Lucci, 2010; Demaria et al., 2012; De Waele & Pasini, 2013; Ercolani et al., 2013; Columbu et al., 2015; Lucci & Piastra, 2015; Tedeschi et al., 2015) and of Sicily (Madonia & Vattano, 2011). Sinkholes related to Permo-Triassic gypsum have been studied in Friuli Venezia Giulia (Zini et al., 2015). This presentation will review the state of the art regarding different aspects of evaporite karst in Italy focusing on the main new results. References Chiesi M., et al. (2010) - Origin and evolution of a salty gypsum/anhydrite karst spring: the case of Poiano (Northern Apennines, Italy). Hydrogeology Journal, 18, pp. 1111-1124. Columbu A. et al. (2015) - Gypsum caves as indicators of climate-driven river incision and aggradation in a rapidly uplifting region. Geology, 43(6), 539-542. Demaria D. et al. (Eds.) (2012), Le Grotte Bolognesi, GSB-USB, 431 p. De Waele J., Pasini G. (2013) - Intra-messinian gypsum palaeokarst in the northern Apennines and its palaeogeographic implications. Terra Nova 25, pp. 199-205. Ercolani M., et al. (Eds.) (2013), I Gessi e la Cave i Monte Tondo. Studio multidisciplinare di un'area carsica nella Vena del Gesso Romagnola. Memorie Ist. It. Spel. II(26), 559 p

Epidemiology of clinical trials of medicines in respiratory diseases in Europe and Italy.

PubMed

Bodini, Roberta; Santus, Pierachille; Di Marco, Fabiano; Aliberti, Stefano; Centanni, Stefano; Blasi, Francesco; Rizzi, Andrea; Recchia, Giuseppe

2017-04-01

Clinical trials play a key role in advancing medical knowledge, improving patient care and promoting economic growth in Europe. We have assessed the clinical trial activity in any respiratory diseases in Europe, with a specific focus on Italy. Information from public sources (EFPIA, clinicaltrials.gov, clinicaltrialsregister. eu, AIFA) was used to describe clinical trial activity of in respiratory diseases in Europe and by country. In 2015, 3908 clinical trials were reported in Europe, 386 in respiratory diseases (9.9%). Germany was the first country both as absolute number (76 trials) and as percentage within country trials (14%), followed by Poland. Spain, Italy and France were the countries with the lowest number and percentage of trials in respiratory diseases. In 2013, the Italian Drug Agency reported 9 trials with respiratory compounds in Italy (2.1% of overall trials, 12ˆ position in the therapeutic area rank), 33% in phase 2 and 66% in phase 3. No phase 1 or phase 4 trials were reported for respiratory trials. Prevalence of respiratory trials by non-profit sponsors (28.3%) was below the average for the country (38.3%). Europe has a greater potential for clinical research on drugs for respiratory diseases, particularly in countries with less activity, such as Spain, France and Italy, that should identify and implement actions to increase attractiveness for clinical trials of drugs. Copyright © 2017 Elsevier Ltd. All rights reserved.

Vitamin D deficiency in refugees in Italy.

PubMed

De Filippis, L G; Trombetta, I; Novella, T; Alampi, M

2017-09-21

The objective of the research is to determine 25[OH]D serum levels in refugees in Italy. In the following research we have taken into consideration the results of the monitoring of Vitamin D levels in 46 refugees of the Italian Service for protection of refugees and asylum seekers (SPRAR) system. The indicator of overall vitamin D status used was the circulating serum level of 25(OH)D. Data was analyzed using Microsoft Excel. In the refugees tested, the mean level of 25(OH)D resulted 9.18 ng/mL. The standard deviation was 4.8, with a minimal level of 4.3 and a maximum of 27.4. This figure indicates a clear condition of hypovitaminosis in refugees. While it is general assumption that migratory phenomena may induce the spread of tropical or infectious diseases, widely attested literature demonstrates how chronic pathologies and diseases related to altered lifestyles are the most relevant for Italian case records. Indeed, among the aforementioned diseases, Vitamin D deficiency so far lacks acknowledgement at a national level. Considering the results of lower-than-desirable vitamin D levels found in refugees in Italy, it is necessary to take this parameter into consideration when analyzing individuals who have faced migratory phenomena in order to mitigate the effects of hypovitaminosis D.

Bladder cancer and occupation: a case-control study in northern Italy.

PubMed Central

Porru, S; Aulenti, V; Donato, F; Boffetta, P; Fazioli, R; Cosciani Cunico, S; Alessio, L

1996-01-01

OBJECTIVES--A hospital based case-control study was conducted between 1992 and 1993 in the province of Brescia, a highly industrialised area in northern Italy, to evaluate occupational risk factors of bladder cancer. METHODS--The study evaluated 355 histologically confirmed cases of bladder cancer (275 men, 80 women) and 579 controls affected by urological non-neoplastic diseases (397 men, 182 women). Lifetime occupational history, smoking and drinking habits, and sociodemographic characteristics were recorded by means of a structured questionnaire. Odds ratios (ORs) were computed with adjustment for age, smoking, alcohol and coffee consumption, education, and place of residence. RESULTS--A significant (P < 0.05) increase of risk of bladder cancer were found in men for labourers in the construction industry (OR 2.1, 95% confidence interval (95% CI) 1.1-3.9) and for recreational and cultural services (OR 5.0, 95% CI 1.3-18.9). Increased risks, although not significant, were found for various other occupations and industries such as machinery mechanics, metal processers and polishers, blacksmiths, gunsmiths, painters; for transport workers, an increased risk with increasing duration of employment was found. CONCLUSIONS--Occupational exposures seem to contribute to bladder cancer risk in the area under study. PMID:8563860

Nardo Ring, Italy

NASA Technical Reports Server (NTRS)

2008-01-01

The Nardo Ring is a striking visual feature from space, and astronauts have photographed it several times. The Ring is a race car test track; it is 12.5 kilometers long and steeply banked to reduce the amount of active steering needed by drivers. The Nardo Ring lies in a remote area on the heel of Italy's 'boot,' 50 kilometers east of the naval port of Taranto. The Ring encompasses a number of active (green) and fallow (brown to dark brown) agricultural fields. In this zone of intensive agriculture, farmers gain access to their fields through the Ring via a series of underpasses. Winding features within the southern section of the Ring appear to be smaller, unused race tracks.

The image covers an area of 18.8 x 16.4 km, was acquired on August 17. 2007, and is located at 49.3 degrees north latitude, 17.8 degrees east longitude.

The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

Radiolabeling and in vitro and in vivo characterization of [18F]FB-[R(8,15,21), L17]-VIP as a PET imaging agent for tumor overexpressed VIP receptors.

PubMed

Cheng, Dengfeng; Yin, Duanzhi; Li, Gucai; Wang, Mingwei; Li, Shiqiang; Zheng, Mingqiang; Cai, Hancheng; Wang, Yongxian

2006-12-01

In an effort to develop a peptide-based radiopharmaceutical for the detection of tumors overexpressed vasoactive intestinal peptide receptors with positron emission tomography, we have prepared a novel [R(8,15,21), L17]-VIP peptide for 18F-labeling. This peptide inhibited 125I-VIP binding to rats lung membranes with high affinity [half-maximal inhibitory concentrations (IC50) of 0.12 nm]. Additionally, [R(8,15,21), L17]-VIP showed higher stability than native vasoactive intestinal peptide in vivo of mice. With N-succinimidyl 4-[18F] fluorobenzoate as labeling prosthetic group, [18F]FB-[R(8,15,21), L17]-VIP was obtained in >99% radiochemical purity within 100 min in decay-for-corrected radiochemical yield of 33.6 +/- 3% (n = 5) and a specific radioactivity 255 GBq/micromol at the end of synthesis. Stability of [18F]FB-[R(8,15,21), L17]-VIP in vitro and in vivo were investigated. Biodistribution of this trace was carried out in mice with induced C26 colorectal tumor. Fast clearance of [18F]FB-[R(8,15,21), L17]-VIP from non-target tissues and specific uptakes by tumors realized higher tumor-to-muscle ratio (3.55) and tumor-to-blood ratio (2.37) 60 min postinjection. Clear difference was observed between the blocking and unblocking experiments in biodistribution and whole body radioautography. [18F]FB-[R(8,15,21), L17]-VIP has demonstrated its potential for diagnosing tumors overexpressed vasoactive intestinal peptide receptors both in vitro and in vivo.

Foreign children with cancer in Italy

PubMed Central

2011-01-01

Background There has been a noticeable annual increase in the number of children coming to Italy for medical treatment, just like it has happened in the rest of the European Union. In Italy, the assistance to children suffering from cancer is assured by the current network of 54 centres members of the Italian Association of Paediatric Haematology and Oncology (AIEOP), which has kept records of all demographic and clinical data in the database of Mod.1.01 Registry since 1989. Methods We used the information stored in the already mentioned database to assess the impact of immigration of foreign children with cancer on centres' activity, with the scope of drawing a map of the assistance to these cases. Results Out of 14,738 cases recorded by all centres in the period from 1999 to 2008, 92.2% were born and resident in Italy, 4.1% (608) were born abroad and living abroad and 3.7% (538) were born abroad and living in Italy. Foreign children cases have increased over the years from 2.5% in 1999 to. 8.1% in 2008. Most immigrant children came from Europe (65.7%), whereas patients who came from America, Asia and Oceania amounted to 13.2%, 10.1%, 0.2%, respectively. The immigrant survival rate was lower compared to that of children who were born in Italy. This is especially true for acute lymphoblastic leukaemia patients entered an AIEOP protocol, who showed a 10-years survival rate of 71.0% vs. 80.7% (p < 0.001) for immigrants and patients born in Italy, respectively. Conclusions Children and adolescents are an increasingly important part of the immigration phenomenon, which occurs in many parts of the world. In Italy the vast majority of children affected by malignancies are treated in AIEOP centres. Since immigrant children are predominantly treated in northern Italy, these centres have developed a special expertise in treating immigrant patients, which is certainly very useful for the entire AIEOP network. PMID:21923939

Changing Dietary Habits of Alberta Nutrition Students Enrolled in a Travel Study Program in Italy.

PubMed

Strawson, Cynthia; Bell, Rhonda C; Farmer, Anna; Downs, Shauna M; Olstad, Dana L; Willows, Noreen D

2015-06-01

This study describes dietary changes among university students who completed a travel study program. Seventeen undergraduate nutrition students travelled from Edmonton to Italy for 6 weeks to take 2 courses on the Mediterranean diet. In both locations students completed a 24-h dietary recall and a Food Frequency Questionnaire to assess their Mediterranean Diet Quality Index Score (MDQIS). A MDQIS of 48 indicates perfect adherence to eating patterns of the Traditional Healthy Mediterranean Diet Pyramid (THMDP). While in Italy students altered their diets in positive ways (increased consumption of fish and seafood (P = 0.002), wine (P < 0.0001), and olive oil (P = 0.001)) and negative ways (increased consumption of sweets (P = 0.027), poultry (P = 0.001), and meat (P = 0.049)) relative to the THMDP. Students had a significant increase in the percentage of energy from polyunsaturated and monounsaturated fatty acids and alcohol. The MDQIS was low in Edmonton (21.9 ± 3.7) and Italy (22.9 ± 3.9). The overall dietary pattern of students did not adhere to the THMDP. Education about the THMDP and living in Italy for 6 weeks was insufficient to change students' dietary patterns to one characterized as traditional Mediterranean. The findings highlight the challenges of implementing dietary changes even with nutrition education and increased food access.

The Bologna Process in Italy

ERIC Educational Resources Information Center

Ballarino, Gabriele; Perotti, Loris

2012-01-01

Italy was among the promoters of the Bologna Process and the early adopters of the reform. If one looks at its impact on the formal structure of curricula and study programmes, the reform undertaken under the Bologna banner seems to have been one of the major educational reforms ever achieved in Italy. This article describes how the Bologna…

[Reduction of meat consumption and greenhouse gas emissions associated with health benefits in Italy].

PubMed

Farchi, Sara; Lapucci, Enrica; Michelozzi, Paola

2015-01-01

the reduction in red meat consumption has been proposed as one of the climate change mitigation policies associated to health benefits. In the developed world, red meat consumption is above the recommended intake level. the aim is to evaluate health benefits, in term of mortality decline, associated to different bovine meat consumption reduction scenarios and the potential reduction in greenhouse gas (GHG) emissions. meat consumption in Italy has been estimated using the Italian National Food Consumption Survey INRAN-SCAI (2005-2006) and the Multipurpose survey on household (2012) of the Italian National Institute for Statistics. Colorectal cancer and stoke mortality data are derived from the national survey on causes of death in 2012. Bovine meat consumption risk function has been retrieved from systematic literature reviews. Mean meat consumption in Italy is equal to 770 grams/week; gender and geographical variations exist: 69 per cent of the adult population are habitual bovine meat consumers; males have an average intake of over 400 grams/week in all areas of Italy (with the exception of the South), while females have lower intakes (360 grams per week), with higher consumption in the North-West (427 gr) and lower in the South of Italy. Four scenarios of reduction of bovine meat consumption (20%, 40%, 50% e 70%, respectively) have been evaluated and the number of avoidable deaths by gender and area of residence have been estimated. GHG emissions attributed to bovine meat adult consumption have been estimated to be to 10 gigagrams CO2-eq. from low to high reduction scenario, the percentage of avoidable deaths ranged from 2.1% to 6.5% for colorectal cancer and from 1.6% to 5.6% for stroke. Health benefits were greatest for males and for people living in the North-Western regions of Italy. in Italy, in order to adhere to bovine meat consumption recommendations and to respect EU GHG emission reduction targets, scenarios between 50% and 70% need to be adopted.

Communication strategies to address geohydrological risks: the POLARIS web initiative in Italy

NASA Astrophysics Data System (ADS)

Salvati, Paola; Pernice, Umberto; Bianchi, Cinzia; Marchesini, Ivan; Fiorucci, Federica; Guzzetti, Fausto

2016-06-01

Floods and landslides are common phenomena that cause serious damage and pose a severe threat to the population of Italy. The social and economic impact of floods and landslides in Italy is severe, and strategies to target the mitigation of the effects of these phenomena are needed. In the last few years, the scientific community has started to use web technology to communicate information on geohydrological hazards and the associated risks. However, the communication is often targeted at technical experts. In the attempt to communicate relevant information on geohydrological hazards with potential human consequences to a broader audience, we designed the POpoLazione A RISchio (POLARIS) website. POLARIS publishes accurate information on geohydrological risk to the population of Italy, including periodic reports on landslide and flood risk, analyses of specific damaging events and blog posts on landslide and flood events. By monitoring the access to POLARIS in the 21-month period between January 2014 and October 2015, we found that access increased during particularly damaging geohydrological events and immediately after the website was advertised by press releases. POLARIS demonstrates that the scientific community can implement suitable communication strategies that address different societal audiences, exploiting the role of mass media and social media. The strategies can help multiple audiences understand how risks can be reduced through appropriate measures and behaviours, contributing to increasing the resilience of the population to geohydrological risk.

Three different Hepatozoon species in domestic cats from southern Italy.

PubMed

Giannelli, Alessio; Latrofa, Maria Stefania; Nachum-Biala, Yaarit; Hodžić, Adnan; Greco, Grazia; Attanasi, Anna; Annoscia, Giada; Otranto, Domenico; Baneth, Gad

2017-08-01

Three species of Hepatozoon, namely, Hepatozoon felis, Hepatozoon canis and Hepatozoon silvestris may affect domestic and/or wild felids. Although hepatozoonosis has been documented in a wide range of mammal species, data on cats are limited. To investigate the occurrence of these pathogens in cats, blood samples were collected from animals living in three provinces of southern Italy (Bari, Lecce, and Matera), and molecularly analysed by PCR amplification and sequencing of segments of the 18S rRNA gene. Out of 196 blood samples collected, Hepatozoon spp. DNA was amplified in ten cats (5.1%, CI: 3%-9%), with the majority of infected animals from Matera (8/34, 23.5%) and one each from the other two provinces. BLAST analysis revealed the highest nucleotide identity with sequences of H. canis, H. felis and H. silvestris deposited in GenBank. Results of this study indicate that these three species of Hepatozoon infect domestic cats in Italy. This is the first report of H. silvestris infection in a domestic cat. Copyright © 2017 Elsevier GmbH. All rights reserved.

The direct and indirect cost of diabetes in Italy: a prevalence probabilistic approach.

PubMed

Marcellusi, A; Viti, R; Mecozzi, A; Mennini, F S

2016-03-01

Diabetes mellitus is a chronic degenerative disease associated with a high risk of chronic complications and comorbidities. However, very few data are available on the associated cost. The objective of this study is to identify the available information on the epidemiology of the disease and estimate the average annual cost incurred by the National Health Service and Society for the Treatment of Diabetes in Italy. A probabilistic prevalence cost of illness model was developed to calculate an aggregate measure of the economic burden associated with the disease, in terms of direct medical costs (drugs, hospitalizations, monitoring and adverse events) and indirect costs (absenteeism and early retirement). A systematic review of the literature was conducted to determine both the epidemiological and economic data. Furthermore, a one-way and probabilistic sensitivity analysis with 5,000 Monte Carlo simulations was performed to test the robustness of the results and define a 95% CI. The model estimated a prevalence of 2.6 million patients under drug therapies in Italy. The total economic burden of diabetic patients in Italy amounted to €20.3 billion/year (95% CI €18.61 to €22.29 billion), 54% of which are associated with indirect costs (95% CI €10.10 to €11.62 billion) and 46% with direct costs only (95% CI €8.11 to €11.06 billion). This is the first study conducted in Italy aimed at estimating the direct and indirect cost of diabetes with a probabilistic prevalence approach. As might be expected, the lack of information means that the real burden of diabetes is partly underestimated, especially with regard to indirect costs. However, this is a useful approach for policy makers to understand the economic implications of diabetes treatment in Italy.

48 CFR 252.229-7003 - Tax Exemptions (Italy).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Tax Exemptions (Italy... of Provisions And Clauses 252.229-7003 Tax Exemptions (Italy). As prescribed in 229.402-70(c), use the following clause: Tax Exemptions (Italy) (JAN 2002) (a) The Contractor represents that the...

Religious slaughter in Italy.

PubMed

Cenci-Goga, B T; Mattiacci, C; De Angelis, G; Marini, P; Cuccurese, A; Rossi, R; Catanese, B

2010-06-01

This research aims to understand the prevalence of religious slaughter practices in Italy. Two different ways of slaughtering animals are identified. Conventional slaughter is performed with prior stunning; kosher slaughter is practiced without stunning. Halal slaughter is performed for most animals without stunning. Halal slaughter with prior stunning is acceptable for 5.90% of small ruminants. For Halal slaughter in Italy, the terms "religious slaughter with stunning" and "religious slaughter without stunning" should be used to differentiate religious slaughter practices, keeping animal welfare in perspective.

Spirits and liqueurs in European traditional medicine: Their history and ethnobotany in Tuscany and Bologna (Italy).

PubMed

Egea, Teresa; Signorini, Maria Adele; Bruschi, Piero; Rivera, Diego; Obón, Concepción; Alcaraz, Francisco; Palazón, José Antonio

2015-12-04

Fermented drinks, often alcoholic, are relevant in many nutritional, medicinal, social, ritual and religious aspects of numerous traditional societies. The use of alcoholic drinks of herbal extracts is documented in classical pharmacy since the 1st century CE and it is often recorded in ethnobotanical studies in Europe, particularly in Italy, where are used for a wide range of medicinal purposes. Formulations and uses represent a singular tradition which responds to a wide range of environmental and cultural factors. This research has two overarching aims To determine how long ancient uses, recipes and formulas for medicinal liqueurs from the pharmacopoeias and herbals of the 18th century persisted in later periods and their role in present ethnobotanical knowledge in areas of Tuscany and Emilia-Romagna (Italy). To trace other possible relationships among ancient and recent recipes of alcoholic beverages, from both popular and 'classic' (learned) sources in N-C Italy and neighboring areas. The review of herbals and classical pharmacopoeias, and ethnobotanical field work in Alta Valle del Reno (Tuscany and Emilia Romagna, Italy) were followed of a systematic study of ingredients and medicinal uses with multivariate analysis techniques. The multivariate analysis clearly shows six different styles of preparing medicinal alcoholic beverages: 1. The medicinal wine formulae by Dioscorides (1st century CE). 2. The pharmacopoeias of Florence and Bologna in the 18th century CE. 3. The formularies of Santa Maria Novella and Castiglione (19th and early 20th centuries CE). 4. The ethnobotanical data from Appennino Tosco-Emiliano; home-made formulations based almost exclusively on the use of local resources. 5. Traditional recipes from NE Italy and Austria. 6. Traditional recipes from NW Italy, Emilia, and Provence (France). A total of 54 ingredients (29 fruits) from 48 species are used in different combinations and proportions in Alta Valle del Reno (Italy) to produce

Occupational cancer in Italy.

PubMed Central

Merler, E; Vineis, P; Alhaique, D; Miligi, L

1999-01-01

This article is a discussion of occupational cancer in Italy. The introduction provides the necessary context of Italian industrialization and occupational health regulation. This is followed by a review of Italian epidemiologic studies of occupational cancer risks considered in terms of relative measures of risk and attributable risk of carcinogenic agents or exposure circumstances. We attempt to establish the number of workers exposed to carcinogens in Italy and the intensity of their exposures. Finally, the Italian system of compensation for occupational cancer is discussed. Several cohort and case-control studies have addressed the issue of occupational risks, mostly among male workers. The results of these studies suggest that the growing incidence of and mortality by mesothelioma is explained by the widespread and intense exposure to asbestos in some Italian industrial settings. A high attributable risk of lung tumors among male populations in industrial areas of northern Italy is explained by occupational exposures. However, insufficient data are available for clear definition of the extent and intensity of occupational exposure to carcinogenic substances. In Italy, we must prioritize and maximize resources in occupational cancer epidemiology and revitalize the role of national institutions. Recent legislation has established new regulations on the handling of carcinogenic substances in industrial settings, a new list of occupational diseases, and a national registry of mesothelioma linked to asbestos exposure. These legislative changes are expected to have positive effects. PMID:10350509

Further circulation of West Nile and Usutu viruses in wild birds in Italy.

PubMed

Llopis, Isis Victoriano; Rossi, Luca; Di Gennaro, Annapia; Mosca, Andrea; Teodori, Liana; Tomassone, Laura; Grego, Elena; Monaco, Federica; Lorusso, Alessio; Savini, Giovanni

2015-06-01

Usutu virus (USUV) and West Nile virus (WNV) are emerging pathogens that can cause neurological disease in humans. From March 2012 to June 2013, a sero-survey on wild birds was carried out to investigate the circulation of both viruses in Northwest (NW) Italy. Samples belonging to 47 different bird species have been collected using a volunteer based network and a wildlife rehabilitation center. Four of 297 serum samples had neutralizing antibodies against USUV (P=1.34%, IC 95% 0.36-3.4), while 10 of 233 samples tested positive for WNV (P=4.29%, IC 95% 2.07-7.75). Neutralizing antibodies for WNV were significantly more prevalent (p<0.001) in trans-Saharan migrants (P=21%, IC 95% 9.55-37.3) than in resident and short-distance birds, but no migratory habit-related differences were found for USUV. Antibodies in resident bird species suggest that both viruses are circulating in NW Italy. Copyright © 2015 Elsevier B.V. All rights reserved.

[Human Papilloma Virus (HPV), cervical cancer incidence and screening uptake: differences among Northern, Central and Southern Italy].

PubMed

Giorgi Rossi, Paolo; Chini, Francesco; Borgia, Piero; Guasticchi, Gabriella; Carozzi, Francesca Maria; Confortini, Massimo; Angeloni, Claudio; Buzzoni, Carlotta; Buonaguro, Franco Maria

2012-01-01

this article presents a review of evidences about Human Papillomavirus (HPV) and cervical cancer in Italy, highlighting geographical differences. two systematic reviews recently published were updated, one collecting studies on the prevalence of HPV types in Italy in the general population and the other collecting prevalence of HPV types in cervical pathologic samples.The search was updated to 31.10.2010 and performed exclusively in MedLine and references in retrieved papers. the prevalence of HPV types has been related with the incidence of cervical cancer and the spread of Pap tests and screening programs. the prevalence high risk HPV types is 8%in studies with population-based random sample, with no significant difference between Centre-North and South-Islands, however, the prevalence is slightly higher in the South than the Centre-North for women up to 54 years of age, whereas in older women the ratio is reversed. HPV 16 is the most common type, while HPV 18 is less frequent, 5% and 1% respectively. The average of HPV 16 positivity is 64% and 68% in CIN2/3 and invasive cancer respectively, while the average of HPV 18 is 7% and 11% in CIN2/3 and invasive cancer respectively. There are no significant differences by geographical area.The incidence of invasive cervical cancer in Italy has been decreasing in recent years changing from 9.2 to 7.7 per 100,000 inhabitants in 10 years. The incidence is lower in South-Islands. Pap test coverage is over 80% in Centre-North and less than 60%in South-Islands. cervical cancer incidence is lower in Southern Italy, while the Pap test coverage is much higher in Centre-Northern Italy. This paradox, until now, has been interpreted as a consequence of a lower HPV prevalence in Southern than Northern regions. Recent studies on HPV prevalence do not confirm this hypothesis. Our interpretation is that in Southern Italy we are facing an epidemiologic scenario in transition where the low cancer incidence is the consequence of a low HPV

Snow in Italy

NASA Image and Video Library

2012-02-24

NASA image acquired February 24, 2012 By late February, 2012, the great European cold wave had begun to loosen its frigid grip, but significant snow still remained in the region. The Moderate Resolution Imaging Spectroradiometer (MODIS) aboard the Aqua satellite captured this true-color image of snow in Italy on February 24 at 12:35 UTC (1:30 p.m. local time). In the north of the image, bright white clouds blanket the region in a broad arc. Snow, which tends to be generally less bright that clouds, covers the Alps in the north of Italy. The Apennine Mountains, which form the backbone of the Italian peninsula, also carry a blanket of snow. Although clouds and snow can, at times, be distinguished visually in a true-color image, sometimes they can appear very similar. When it is important to clearly define snow from cloud, false color images are often helpful. Rome, which can be seen as a gray smudge on the southwestern coast of the peninsula, recorded highs of a spring-like 50°F the day this image was captured, but earlier in the month the temperatures dove as low as 26°F on February 5. During that cold snap a rare intense snowfall blanketed Rome, causing the closure of the Colosseum, the Roman Forum and the Palatine Hill due to concerns of the risk of icy footing for tourists, and roads became impassible. Further north, temperatures plummeted to −21 °C (−6 °F) on 7 February. On February 11, news media reported over 2 meters (6.5 feet) of snow had fallen in Urbino, a walled town situated on a high sloping hillside on the eastern side of the Apennine Mountains. That same snowfall cut access to many remote towns in the Apennines, blocking roads and trapping some people in the homes. Credit: NASA/GSFC/Jeff Schmaltz/MODIS Land Rapid Response Team NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA�

Veneto Region, Italy. Health system review.

PubMed

Toniolo, Franco; Mantoan, Domenico; Maresso, Anna

2012-01-01

The Health Systems in Transition (HiT) profiles are country-based reports that provide a detailed description of a health system and of policy initiatives in progress or under development. This HiT is one of the first to be written on a subnational level of government and focuses on the Veneto Region of northern Italy. HiTs examine different approaches to the organization, financing and delivery of health services and the role of the main actors in health systems; describe the institutional framework, process, content and implementation of health and health care policies; and highlight challenges and areas that require more in-depth analysis. The Veneto Region is one of Italy's richest regions and the health of its resident population compares favourably with other regions in Italy. Life expectancy for both men and women, now at 79.1 and 85.2 years, respectively, is slightly higher than the national average, while mortality rates are comparable to national ones. The major causes of death are tumours and cardiovascular diseases. Under Italy's National Health Service, the organization and provision of health care is a regional responsibility and regions must provide a nationally defined (with regional input) basic health benefit package to all of their citizens; extra services may be provided if budgets allow. Health care is mainly financed by earmarked central and regional taxes, with regions receiving their allocated share of resources from the National Health Fund. Historically, health budget deficits have been a major problem in most Italian regions, but since the early 2000s the introduction of efficiency measures and tighter procedures on financial management have contributed to a significant decrease in the Veneto Regions health budget deficit.The health system is governed by the Veneto Region government (Giunta) via the Departments of Health and Social Services, which receive technical support from a single General Management Secretariat. Health care is

Group Psychotherapy in Italy.

PubMed

Giannone, Francesca; Giordano, Cecilia; Di Blasi, Maria

2015-10-01

This article describes the history and the prevailing orientations of group psychotherapy in Italy (psychoanalytically oriented, psychodrama, CBT groups) and particularly group analysis. Provided free of charge by the Italian health system, group psychotherapy is growing, but its expansion is patchy. The main pathways of Italian training in the different group psychotherapy orientations are also presented. Clinical-theoretical elaboration on self development, psychopathology related to group experiences, and the methodological attention paid to objectives and methods in different clinical groups are issues related to group therapy in Italy. Difficulties in the relationship between research and clinical practice are discussed, as well as the empirical research network that tries to bridge the gap between research and clinical work in group psychotherapy. The economic crisis in Italy has led to massive cuts in health care and to an increasing demand for some forms of psychological treatment. For these reasons, and because of its positive cost-benefit ratio, group psychotherapy is now considered an important tool in the national health care system to expand the clinical response to different forms of psychological distress.

Vegetation history and palaeoclimate of the last glacial period at Lago Grande di Monticchio, Southern Italy

NASA Astrophysics Data System (ADS)

Watts, W. A.; Allen, J. R. M.; Huntley, B.

A high-resolution palynological study of a 51 m core from Lago Grande di Monticchio, southern Italy, has provided a palaeonvironmental record for the last glacill. A annual lamination based chronology, supported by radiometric and tephrochronological dates, provides an absolute timescale for this record that spans 76,300 years. Correlations are established between the pollen stratigraphy, the GRIP ice core δ18O record and foraminiferal assemblages from Atlantic core V23-81. Both Dansgaard-Oeschger and Heinrich events are reflected by changes in the pollen stratigraphy. Revised dates are estimated for Heinrich events H1-H6. A quantitative palaeoclimate reconstruction based upon the pollen data provides evidence of the climate changes in southern Italy associated with these and other fluctuations during the last glacial.

Detection and Genotyping of Human Papillomavirus in Urine Samples from Unvaccinated Male and Female Adolescents in Italy

PubMed Central

Bianchi, Silvia; Frati, Elena Rosanna; Panatto, Donatella; Martinelli, Marianna; Amicizia, Daniela; Zotti, Carla Maria; Martinese, Morena; Bonanni, Paolo; Boccalini, Sara; Coppola, Rosa Cristina; Masia, Giuseppina; Meloni, Angelo; Castiglia, Paolo; Piana, Andrea; Gasparini, Roberto; Tanzi, Elisabetta

2013-01-01

The introduction of vaccination against Human Papillomavirus (HPV) in adolescent girls in 2006 has focused virological surveillance on this age group. As few studies have evaluated HPV infections in young populations, further data are needed in order to improve and extend prophylactic policy and to monitor epidemiological changes. The present study aimed at evaluating overall and type-specific HPV prevalence in both female and male adolescents in Italy. HPV DNA detection and genotyping was performed on urine samples collected from 870 unvaccinated adolescents (369 females, 501 males, 11-18 years of age) in five cities in Italy. Following DNA extraction by means of a commercial kit (NucliSENS®-miniMAG®, bioMérieux), the L1 gene fragment was PCR amplified and genotyped by restriction fragment length polymorphism analysis. HPV DNA was detected in 1.5% of all samples, and in 3% and 0.4% of samples from females and males, respectively. In approximately 70% of HPV DNA positive adolescents, the infection was due to a single genotype, with 88.9% of genotypes belonging to the HR-clade. The only two HPV-positive boys (14 and 18 years old) had HPV-70 genotype. Only one of the 11 HPV-infected girls was in the 11-14 age-group. HPV prevalence was 4.2% in girls aged 15-18 years and 60% of infections were due to vaccine types HPV-16 or HPV-6/-11. This is one of the few studies, the first conducted in Italy, on HPV infection in adolescents. Urine testing is the easier way of detecting HPV infection in younger populations. Our data revealed a very low HPV prevalence, and no infections were observed in the 12-year-old vaccine target population. The majority of infections were seen in females aged 15-18 years. Overall, more than 50% and 30% of the potentially persistent HPV infections detected in this group could have been prevented by the quadrivalent and the bivalent vaccines, respectively. PMID:24255711

Detection and genotyping of human papillomavirus in urine samples from unvaccinated male and female adolescents in Italy.

PubMed

Bianchi, Silvia; Frati, Elena Rosanna; Panatto, Donatella; Martinelli, Marianna; Amicizia, Daniela; Zotti, Carla Maria; Martinese, Morena; Bonanni, Paolo; Boccalini, Sara; Coppola, Rosa Cristina; Masia, Giuseppina; Meloni, Angelo; Castiglia, Paolo; Piana, Andrea; Gasparini, Roberto; Tanzi, Elisabetta

2013-01-01

The introduction of vaccination against Human Papillomavirus (HPV) in adolescent girls in 2006 has focused virological surveillance on this age group. As few studies have evaluated HPV infections in young populations, further data are needed in order to improve and extend prophylactic policy and to monitor epidemiological changes. The present study aimed at evaluating overall and type-specific HPV prevalence in both female and male adolescents in Italy. HPV DNA detection and genotyping was performed on urine samples collected from 870 unvaccinated adolescents (369 females, 501 males, 11-18 years of age) in five cities in Italy. Following DNA extraction by means of a commercial kit (NucliSENS(®)-miniMAG(®), bioMérieux), the L1 gene fragment was PCR amplified and genotyped by restriction fragment length polymorphism analysis. HPV DNA was detected in 1.5% of all samples, and in 3% and 0.4% of samples from females and males, respectively. In approximately 70% of HPV DNA positive adolescents, the infection was due to a single genotype, with 88.9% of genotypes belonging to the HR-clade. The only two HPV-positive boys (14 and 18 years old) had HPV-70 genotype. Only one of the 11 HPV-infected girls was in the 11-14 age-group. HPV prevalence was 4.2% in girls aged 15-18 years and 60% of infections were due to vaccine types HPV-16 or HPV-6/-11. This is one of the few studies, the first conducted in Italy, on HPV infection in adolescents. Urine testing is the easier way of detecting HPV infection in younger populations. Our data revealed a very low HPV prevalence, and no infections were observed in the 12-year-old vaccine target population. The majority of infections were seen in females aged 15-18 years. Overall, more than 50% and 30% of the potentially persistent HPV infections detected in this group could have been prevented by the quadrivalent and the bivalent vaccines, respectively.

Epidemiology and costs of cervical cancer screening and cervical dysplasia in Italy

PubMed Central

Rossi, Paolo Giorgi; Ricciardi, Alessandro; Cohet, Catherine; Palazzo, Fabio; Furnari, Giacomo; Valle, Sabrina; Largeron, Nathalie; Federici, Antonio

2009-01-01

Background We estimated the number of women undergoing cervical cancer screening annually in Italy, the rates of cervical abnormalities detected, and the costs of screening and management of abnormalities. Methods The annual number of screened women was estimated from National Health Interview data. Data from the Italian Group for Cervical Cancer Screening were used to estimate the number of positive, negative and unsatisfactory Pap smears. The incidence of CIN (cervical intra-epithelial neoplasia) was estimated from the Emilia Romagna Cancer Registry. Patterns of follow-up and treatment costs were estimated using a typical disease management approach based on national guidelines and data from the Italian Group for Cervical Cancer Screening. Treatment unit costs were obtained from Italian National Health Service and Hospital Information System of the Lazio Region. Results An estimated 6.4 million women aged 25–69 years undergo screening annually in Italy (1.2 million and 5.2 million through organized and opportunistic screening programs, respectively). Approximately 2.4% of tests have positive findings. There are approximately 21,000 cases of CIN1 and 7,000–17,000 cases of CIN2/3. Estimated costs to the healthcare service amount to €158.5 million for screening and €22.9 million for the management of cervical abnormalities. Conclusion Although some cervical abnormalities might have been underestimated, the total annual cost of cervical cancer prevention in Italy is approximately €181.5 million, of which 87% is attributable to screening. PMID:19243586

Direct reconstruction of p-p elastic scattering amplitudes at 1.8 and 2.1 GeV

NASA Astrophysics Data System (ADS)

Ghahramany, Nader; Forozani, Ghasem

2000-06-01

The direct reconstruction of the proton-proton elastic-scattering complex amplitudes is carried out at 1.8 and 2.1 GeV. Five independent amplitudes both in helicity and transversity frame were obtained by using an extensive set of data measured recently at SATURNE II and by the EDDA (COSY) Collaboration. The real and imaginary parts of the amplitudes are plotted versus different interpolated c.m. angles for both frames. Four distinct sets of solutions exist, one of which is chosen on the basis of minimum χ2.

Robotic surgery in Italy national survey (2011).

PubMed

Santoro, Eugenio; Pansadoro, Vito

2013-03-01

Robotic surgery in Italy has become a clinical reality that is gaining increasing acceptance. As of 2011 after the United States, Italy together with Germany is the country with the largest number of active Robotic centers, 46, and da Vinci Robots installed, with at least 116 operators already trained. The number of interventions performed in Italy in 2011 exceeded 6,000 and in 2010 were 4,784, with prevalence for urology, general surgery and gynecology, however these interventions have also begun to be applied in other fields such as cervicofacial, cardiothoracic and pediatric surgery. In Italy Robotic centers are mostly located in Northern Italy, while in the South there are only a few centers, and four regions are lacking altogether. Of the 46 centers which were started in 1999, the vast majority is still operational and almost half handle over 200 cases a year. The quality of the work is also especially high with large diffusion of radical prostatectomy in urology and liver resection and colic in general surgery. The method is very well accepted among operators, over 80 %, and among patients, over 95 %. From the analysis of world literature and a survey carried out in Italy, Robotic surgery, which at the moment could be better defined as telesurgery, represents a significant advantage for operators and a consistent gain for the patient. However, it still has important limits such as high cost and non-structured training of operators.

The burden of rare cancers in Italy: the surveillance of rare cancers in Italy (RITA) project.

PubMed

Trama, Annalisa; Mallone, Sandra; Ferretti, Stefano; Meduri, Francesca; Capocaccia, Riccardo; Gatta, Gemma

2012-01-01

The project Surveillance of rare cancers in Italy (RITA) provides, for the first time, estimates of the burden of rare cancers in Italy based on the list of rare cancers proposed in collaboration with the European project Surveillance of Rare Cancers in Europe (RARECARE). RITA analyzed data from Italian population-based cancer registries (CR). The period of diagnosis was 1988 to 2002, and vital status information was available up to December 31, 2003. Incidence rates were estimated for the period 1995-2002, survival for the years 2000-2002 (with the period method of Brenner), and complete prevalence at January 1, 2003. Rare cancers are those with an incidence <6/100,000/year. In Italy, every year there are 60,000 new diagnoses of rare cancers corresponding to 15% of all new cancer diagnoses. Five-year relative survival was on the average worse for rare cancers (53%) than for common cancers (73%). A total of 770,000 patients were living in Italy in 2008 with a diagnosis of a rare cancer, 22% of the total cancer prevalence. Our estimates constitute a useful base for further research and support the idea that rare cancers are a public health problem that deserves attention. Centers of expertise for rare cancers that pool cases, expertise and resources could ensure an adequate clinical management for these diseases. Our data also showed that cancer registries are suitable sources of data to estimate incidence, prevalence and survival for rare cancers and should continue to monitoring rare cancers in Italy.

Characteristics of Young Adult (Aged 18-25) and Youth (Aged 12-17) Admissions: 2004. The DASIS Report. Issue 21

ERIC Educational Resources Information Center

Substance Abuse and Mental Health Services Administration, 2006

2006-01-01

This report compares young adult admissions to admissions of youths aged 12 to 17, who accounted for 8 percent of Treatment Episode Data Set (TEDS) admissions in 2004. The report further breaks down the young adult admissions into two subgroups: those aged 18 to 21 (9 percent of all admissions); and those aged 22 to 25 (12 percent of all…

Feeding practices of infants through the first year of life in Italy.

PubMed

Giovannini, M; Riva, E; Banderali, G; Scaglioni, S; Veehof, S H E; Sala, M; Radaelli, G; Agostoni, C

2004-04-01

To investigate infant feeding practices through the first year of life in Italy, and to identify factors associated with the duration of breastfeeding and early introduction of solid foods. Structured phone interviews on feeding practices were conducted with 2450 Italian-speaking mothers randomly selected among women who delivered a healthy-term singleton infant in November 1999 in Italy. Interviews were performed 30 d after delivery and when the infants were aged 3, 6, 9 and 12 mo. Type of breastfeeding was classified according to the WHO criteria. Breastfeeding started in 91.1% of infants. At the age of 6 and 12 mo, respectively, 46.8% and 11.8% of the infants was still breastfed, 68.4% and 27.7% received formula, and 18.3% and 65.2% were given cow's milk. Solids were introduced at the mean age of 4.3 mo (range 1.6-6.5 mo). Introduction of solids occurred before age 3 and 4 mo in 5.6% and 34.2% of infants, respectively. The first solids introduced were fruit (73.1%) and cereals (63.9%). The main factors (negatively) associated with the duration of breastfeeding were pacifier use (p < 0.0001), early introduction of formula (p < 0.0001), lower mother's age (p < 0.01) and early introduction of solids (p = 0.05). Factors (negatively) associated with the introduction of solids foods before the age of 3 mo were mother not having breastfed (p < 0.01), early introduction of formula (p < 0.01), lower infant bodyweight at the age of 1 mo (p = 0.05) and mother smoking (p = 0.05). The duration of breastfeeding in Italy is still inadequate, as well as compliance with international recommendations for timing of introduction of complementary foods. National guidelines, public messages and educational campaigns should be promoted in Italy.

[Petechial typhus in Napoleonic Italy. Scientific debate and the role of Giovanni Rasori].

PubMed

Sabbatani, Sergio

2006-12-01

During the Napoleonic wars, an epidemic recrudescence of petechial typhus was observed throughout Europe. In Italy, the epidemic first broke out in Genoa, in 1799, coming from southern France, during the sieges of the Austro-Hungarian army. Giovanni Rasori, a young Republican physician and man of the sciences, supported the besieged and contributed to defend the city. From the beginning, Rasori identified the cause of the epidemic in petechial typhus, being able to evaluate its clinical presentation, and developed a pathogenetic theory, known as contrastimulus. At that time, this theory obtained some success, though opposed by the academic establishment in Lombardy. In this article, we present the medical and philosophical ideas which, in the period between the 18th and 19th century, pervaded medical Italian culture. Furthermore, a biographic profile of Giovanni Rasori is described, a courageous scientist who did not disdain to take part in political and cultural Italian life during a historical period that was to become important for the future fortunes of Italy.

Tobacco sales to minors in Italy.

PubMed

Gallus, Silvano; Tramacere, Irene; Zuccaro, Piergiorgio; Colombo, Paolo; La Vecchia, Carlo

2009-01-01

One of the strategies to control tobacco is to limit purchase of cigarettes to minors. To understand the attitudes of Italian adults towards regulations to prevent minors from purchasing tobacco products, we added specific questions to the annual survey on smoking in Italy. During March-April 2007, we conducted a survey on smoking on 3,057 subjects representative of the Italian population aged > or = 15 years. Two specific questions were included, one investigating the attitudes towards the proposed legislation prohibiting purchase of tobacco to individuals under 18 years of age (instead of 16 years) as a policy to reduce smoking prevalence and consumption. The second question asked whether the current tobacco sales-to-minors law was observed. Overall, 78% of Italians believed that a restriction of the current tobacco sales-to-minors law could be moderately to extremely effective as a strategy to decrease smoking prevalence and consumption. More than 90% of Italians reported that they had never seen in their lifetime a retailer refusing to sell cigarettes to an adolescent or requesting the minor's identification or age. A restriction of the legislation, increasing to 18 years the minimum age for purchasing tobacco, would limit access to tobacco products by minors, only if adopted together with systematic and effective enforcement measures.

Socioeconomic status and biomedical risk factors in migrants and native tuberculosis patients in Italy

PubMed Central

Pittalis, Silvia; Contini, Silvia; Gualano, Gina; Alma, Mario Giuseppe; Tadolini, Marina; Piccioni, Pavilio; Bocchino, Marialuisa; Matteelli, Alberto; Bonora, Stefano; Di Biagio, Antonio; Franzetti, Fabio; Carbonara, Sergio; Gori, Andrea; Sotgiu, Giovanni; Palmieri, Fabrizio; Ippolito, Giuseppe; Girardi, Enrico

2017-01-01

Action on social determinants is a main component of the World Health Organization End Tuberculosis (TB) Strategy. The aim of the study was to collect information on socioeconomic characteristics and biomedical risk factors in migrant TB patients in Italy and compare it with data collected among Italian TB patients. A cross-sectional study was conducted among TB patients aged ≥18 years over a 12-months enrolment period in 12 major Italian hospitals. Information on education, employment, housing and income was collected, and European Union Statistics on Income and Living Conditions index was used to assess material deprivation. Among migrants, we also analyzed factors associated with severe material deprivation. Migrants were compared with younger (18–64 years) and older (65+ years) Italians patients. Out of 755 patients enrolled (with a median age of 42 years, interquartile range: 31–53), 65% were migrants. Pulmonary, microbiologically confirmed, and new cases were 80%, 73%, and 87% respectively. Prevalence of co-morbidities (i.e. diabetes, chronic kidney disease, neoplastic diseases and use of immunosuppressive drugs) was lower among migrants compared to Italian TB patients, while indicators of socioeconomic status, income and housing conditions were worst in migrants. Forty-six percent of migrants were severely deprived vs. 9% of Italians (p<0.0001, 11.3% and 5.5% among younger and older Italians, respectively). Among migrants, being male, older, irregular, unemployed, with a shorter time spent in Italy, a lower education level, and without a co-morbidity diagnosis were factors associated with severe material deprivation at multi-variable logistic regression. Moreover, socioeconomic indicators for Italian patients did not differ from those reported for the general Italian population, while migrant TB patients seem to have a higher prevalence of severe material deprivation than other migrants residing in Italy. Intervention to address the needs of this

Seismic risk perception in Italy

NASA Astrophysics Data System (ADS)

Crescimbene, Massimo; La Longa, Federica; Camassi, Romano; Pino, Nicola Alessandro; Peruzza, Laura

2014-05-01

Risk perception is a fundamental element in the definition and the adoption of preventive counter-measures. In order to develop effective information and risk communication strategies, the perception of risks and the influencing factors should be known. This paper presents results of a survey on seismic risk perception in Italy conducted from January 2013 to present . The research design combines a psychometric and a cultural theoretic approach. More than 7,000 on-line tests have been compiled. The data collected show that in Italy seismic risk perception is strongly underestimated; 86 on 100 Italian citizens, living in the most dangerous zone (namely Zone 1), do not have a correct perception of seismic hazard. From these observations we deem that extremely urgent measures are required in Italy to reach an effective way to communicate seismic risk. Finally, the research presents a comparison between groups on seismic risk perception: a group involved in campaigns of information and education on seismic risk and a control group.

Assessing chronological age of unaccompanied minors in southern Italy.

PubMed

Nuzzolese, Emilio; Solarino, Biagio; Liuzzi, Claudia; Di Vella, Giancarlo

2011-09-01

The increasing volume of, and subsequent complexities resulting from, migratory flows in the broader context of globalization has led to a range of problems, not only the protection of human rights and disease control but also the identification of those with the right to apply for refugee status and the age assessment of unaccompanied minors. Italy is a magnet for immigration from other countries bordering the Mediterranean Sea because the Italian coasts are within easy reach. In Italy, as in other western countries, unaccompanied asylum seekers deemed to be younger than 18 years face a very different path through the immigration system from that experienced by adults. Generally, adults are subject to immediate deportation or detention in jail. Minors are processed through the juvenile system, where detection is not mandatory; they will often have access to educational programs and may be granted a residency permit. The Section of Legal Medicine of the University of Bari was approached by immigration police authorities and judges to explore the possibility of examining unaccompanied asylum seekers, who claim do be younger than 18 years, to assess their age. A group of forensic pathologists and odontologists performed this evaluation relying on the skeletal maturation as seen on radiographs of the wrist and the pelvis for iliac crests and on an orthopantomograph, together with background information and clinical examination of each individual. Case studies are presented. This article does not attempt to give a definitive account of the different scientific methods for the assessment of age. It is important to understand some of the methods that may be used in an attempt to assess developmental maturity and from which it may be possible to "read off" an approximate chronological age.

Update on the epidemiology of tuberculosis in Italy.

PubMed

Conversano, Michele

2014-05-01

As in many countries in Western Europe, in Italy tuberculosis (TB) is a relatively rare disease. In the last decade its incidence has remained constant at under 10 cases/100,000 inhabitants, the threshold considered to define a country as low prevalence. The epidemiological picture, however, is very different in the countries of Eastern Europe and in Africa, Asia, and Latin America, where the incidence of TB continues to increase and in some cases is accompanied by the emergence and spread of multidrug-resistant TB. The present review describes the epidemiology of TB in Italy. In 2008, the incidence rate was 3.8 cases per 100,000 for people born in Italy, and 50-60 cases per 100,000 for those born abroad. There was an increase in cases from Eastern Europe. The crude mortality rate for TB in 2006 was 0.7 deaths per 100,000 residents. Although TB is a low-prevalence disease in Italy, its epidemiology is changing. Since 1955, more than 160,000 people in Italy have died from this potentially preventable and curable disease.

75 FR 14628 - Pressure Sensitive Plastic Tape From Italy; Determination

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-26

... Plastic Tape From Italy; Determination On the basis of the record \\1\\ developed in the subject five-year... pressure sensitive plastic tape from Italy would be likely to lead to continuation or recurrence of... Publication 4128 (March 2010), entitled Pressure Sensitive Plastic Tape from Italy: Investigation No. AA1921...

Myelin management by the 18.5–kDa and 21.5–kDa classic myelin basic protein isoforms

PubMed Central

Harauz, George; Boggs, Joan M.

2013-01-01

The classic myelin basic protein (MBP) splice isoforms range in nominal molecular mass from 14 to 21.5 kDa, and arise from the gene in the oligodendrocyte lineage (Golli) in maturing oligodendrocytes. The 18.5-kDa isoform that predominates in adult myelin adheres the cytosolic surfaces of oligodendrocyte membranes together, and forms a two-dimensional molecular sieve restricting protein diffusion into compact myelin. However, this protein has additional roles including cytoskeletal assembly and membrane extension, binding to SH3-domains, participation in Fyn-mediated signaling pathways, sequestration of phosphoinositides, and maintenance of calcium homeostasis. Of the diverse post-translational modifications of this isoform, phosphorylation is the most dynamic, and modulates 18.5-kDa MBP’s protein-membrane and protein-protein interactions, indicative of a rich repertoire of functions. In developing and mature myelin, phosphorylation can result in microdomain or even nuclear targeting of the protein, supporting the conclusion that 18.5-kDa MBP has significant roles beyond membrane adhesion. The full-length, early-developmental 21.5-kDa splice isoform is predominantly karyophilic due to a non-traditional P-Y nuclear localization signal, with effects such as promotion of oligodendrocyte proliferation. We discuss in vitro and recent in vivo evidence for multifunctionality of these classic basic proteins of myelin, and argue for a systematic evaluation of the temporal and spatial distributions of these protein isoforms, and their modified variants, during oligodendrocyte differentiation. PMID:23398367

Health websites in Italy: use, classification and international policy.

PubMed

Di Giacomo, Paola; Maceratini, Riccardo

2002-09-01

In this paper, we discuss international policy in relation to the use of health websites and we describe the results obtained from application of a search engine to the recognition and classification of health websites in Italy. We then compare the results with health websites in other countries. Effective use of technology has led to medical advances that have not only extended life expectancy, but also fuelled an increasingly well-informed public to expect more and more from today's healthcare providers. As a consequence of the Web's rapid, chaotic growth, the resulting network of information lacks organization and structure and the quest for a method of quickly finding relevant and reliable information is spawning the growth of Internet portal sites. The US and the European Union and now Italy, have established the importance of rules to check the quality of health sites both for the non-professional users (citizens), mainly for privacy and security (for example, of medical records); and for health operators (physicians and others), where the most important thing is to evaluate the quality of content. In June 2001, the search engine used here found 2627 Italian health sites, of which only 46 exhibited the HON Code, and they can be classified into: 1% personal medical sites, 17% health portals, 18%, metasites, 27% documental sites and 37% information sites for health operators and/or for citizens.

A comparison of survey techniques on sensitive sexual behavior in Italy.

PubMed

Caltabiano, Marcantonio; Dalla-Zuanna, Gianpiero

2013-01-01

This article compares two national surveys carried out through the most commonly used procedures in Italy: CATI (computer-assisted telephone interviews) and SAQ-FI (self-answered questionnaires following interviews). Both surveys ask two identical questions concerning sensitive sexual behavior: early age at first intercourse and same-sex attraction. The SAQ-FI survey had both unit non-response and item non-response rates much lower than the CATI survey. Moreover, in the CATI survey, the groups with highest item non-response rates were also the groups with the lowest proportions of early intercourse and homosexual attraction. In addition, a differential analysis of the respondents produced diverse results for the two surveys. This is especially true of results by gender for same-sex attraction: Such behavior is more common among men (3.1%) than women (2.9%), according to the CATI survey, whereas the opposite is true of the SAQ-FI survey (6.1% of men vs. 7.7% women). In Italy at the beginning of the 21st century, CATI surveys reveal a lower level of early intercourse and same-sex attraction than SAQ-FI surveys. This article argues that the CATI survey underestimates the true level of these sensitive sexual behaviors in the Italian population.

Resilience and Adaptation of Cultural Heritage to Climate Change; International Workshop in Ravello (Italy) 18-19 May 2017

NASA Astrophysics Data System (ADS)

Lefèvre, Roger-Alexandre

2017-04-01

Cultural Heritage is the core of civilization and mankind and contributes substantially to quality of life. Its preservation for its historical value and aesthetics, for its conservation and transmission, must be one of the paramount preoccupations of each citizen and institution. It is therefore fundamental to guard against a major evolution of our planet that is increasing and harmful for all the materials: climate imbalance. The tangible Cultural Heritage, often in an urban environment, is threatened both by extreme climate events, relatively short but recurrent, and by slow, insidious and continuous ones, often in relationship with pollution. The main climate factor at global scale - a general increase of mean temperatures leading to sea level rise - will have direct and indirect consequences on Cultural Heritage. The other climate threats (rain, relative humidity, solar radiation, drought, wind, floods…) and pollution (by gases and particles) will have specific effects on materials of Cultural Heritage, both outdoors (façades of monuments, historical centres of cities, open-air statues, cultural landscapes…) and indoors (museums, libraries, reserves, collections…). Since the 1st International Workshop on « Climate Change and Cultural Heritage » held at the European University Centre for Cultural Heritage in Ravello in May 2009, three important events appeared: • The publication in 2014 of the 5th IPCC Assessment Report. For the first time the Cultural Heritage was cited in an IPCC Report. • The holding in 2015 in Paris of the COP21. Some round-tables were organised during this conference concerning the Cultural Heritage. • The holding the same year in Paris of the International Scientific Conference "Our Common Future under Climate Change" in the frame and ahead of the COP21. Cultural Heritage was the topic of a special session at this important conference. During the last decade, the European scientific community was focused on the Threats and

Knowledge and Attitudes Toward Organ Donation in Health Care Undergraduate Students in Italy.

PubMed

Fontana, F; Massari, M; Giovannini, L; Alfano, G; Cappelli, G

2017-11-01

The number of organ donors in Italy is increasing, but with still disappointing living donation activity and relatively frequent objection by potential deceased donors' relatives to organ recovery. Few studies have assessed health care students' knowledge and attitude on donation. We administered a questionnaire to medical (MS) and nursing students (NS) at University of Modena and Reggio Emilia, Italy, and 749 students (406 MS and 343 NS) completed the questionnaire. Although 95% of students were in favor of donation, only 21.9% of NS and 24.9% of MS were registered as donors. One quarter of students reported family disagreement. MS appeared more confident with personnel involved in donation. Overall, 60% of students knew the term donation after brain death but only 40% were aware of the criteria used to define it. Barely 27.1% of NS and 15.3% of MS believed they had received sufficient information in lessons. Backward logistic regression demonstrated that students whose families agree with them and who knew the definition of donation after brain death were more likely to express the disposition of registering, and those who showed distrust in the declaration of brain death were half as likely to register as donors. Students expressed a lack of knowledge, controversial attitudes on donation, and strong need for education; increased awareness may help increase donation rates. The majority of educational institutions in Italy do not directly address training on organ donation and transplantation for health care students; an integrated curriculum favoring interpersonal discussion including practical aspects is urgently required. Copyright © 2017 Elsevier Inc. All rights reserved.

Large-Scale Assessments and Educational Policies in Italy

ERIC Educational Resources Information Center

Damiani, Valeria

2016-01-01

Despite Italy's extensive participation in most large-scale assessments, their actual influence on Italian educational policies is less easy to identify. The present contribution aims at highlighting and explaining reasons for the weak and often inconsistent relationship between international surveys and policy-making processes in Italy.…

78 FR 36163 - Bitterroot National Forest, Darby Ranger District, Como Forest Health Project

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-17

... Lake Como and Lost Horse Roads, about XX miles northwest of Darby in Ravalli County, Montana. The... Lost Horse Road, about three miles northwest of Darby, Montana (R22W,T4N, Sec. 13, 24, 25, 36; R21W,T4N...

Prevalence of Verocytotoxigenic Escherichia coli strains isolated from raw beef in southern Italy.

PubMed

Nobili, Gaia; Franconieri, Ilenia; La Bella, Gianfranco; Basanisi, Maria Grazia; La Salandra, Giovanna

2017-09-18

Verocytotoxin (VT)-producing Escherichia coli (VTEC) are a significant foodborne public health hazard, where most human infections are associated with six serogroups (O157, O26, O103, O145, O111 and O104). VTEC was the fourth most commonly reported zoonosis in the EU in 2015, with 5901 confirmed human cases. Ruminant animals, including cattle, are a major reservoir of VTEC. The consumption of VTEC-contaminated animal-derived foodstuffs, especially undercooked ground beef, is an important transmission route. To the best of our knowledge, there are few data available on the contamination of VTEC in meat products in Italy. During 2015 and 2016, 250 raw meat samples were collected from retail markets in southern Italy (Apulia) and analysed for the occurrence of vtx genes (vtx1/vtx2) at the Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata (IZS PB, Italy). In addition, the isolates were characterized by determining the presence of VTEC main virulence factors, the antimicrobial resistance profiles and the genetic relatedness by pulsed-field gel electrophoresis (PFGE). The results have shown that 8.4% (21/250) of the samples were positive for vtx genes in the preliminary screening step but VTEC strains were isolated from only 2% (5/250) of overall meat analysed samples, including raw ground beef, beef hamburger and beef carpaccio. 5 isolates displayed a multi-drug resistance phenotype. All VTEC strains were analysed by XbaI-PFGE and dendrogram revealed 5 distinct restriction profiles, indicating their relatively high genetic diversity. Although this study demonstrates a low prevalence of VTEC in raw beef marketed in southern Italy, the presence of potentially pathogenic E. coli strains points to the need for proper hygiene during meat production to reduce the risk of foodborne illness and transmission of multi-drug resistant organisms via foods to humans. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

Perinatal outcomes among immigrant mothers over two periods in a region of central Italy

PubMed Central

2011-01-01

Background The number of immigrants has increased in Italy in the last twenty years (7.2% of the Italian population), as have infants of foreign-born parents, but scanty evidence on perinatal outcomes is available. The aim of this study was to investigate whether infants of foreign-born mothers living in Italy have different odds of adverse perinatal outcomes compared to those of native-born mothers, and if such measures changed over two periods. Methods The source of this area-based study was the regional hospital discharge database that records perinatal information on all births in the Lazio region. We analysed 296,739 singleton births born between 1996-1998 and 2006-2008. The exposure variable was the mother's region of birth. We considered five outcomes of perinatal health. We estimated crude and adjusted odds ratios and 95% confidence intervals (CIs) to evaluate the association between mother's region of birth and perinatal outcomes. Results Perinatal outcomes were worse among infants of immigrant compared to Italian mothers, especially for sub-Saharan and west Africans, with the following crude ORs (in 1996-1998 and 2006-2008 respectively): 1.80 (95%CI:1.44-2.28) and 1.95 (95%CI:1.72-2.21) for very preterm births, and 1.32 (95%CI:1.16-1.50) and 1.32 (95%CI:1.25-1.39) for preterm births; 1.18 (95%CI:0.99-1.40) and 1.17 (95%CI:1.03-1.34) for a low Apgar score; 1.22 (95%CI:1.15-1.31) and 1.24 (95%CI:1.17-1.32) for the presence of respiratory diseases; 1.47 (95%CI:1.30-1.66) and 1.45 (95%CI:1.34-1.57) for the need for special or intensive neonatal care/in-hospital deaths; and 1.03 (95%CI:0.93-1.15) and 1.07 (95%CI:1.00-1.15) for congenital malformations. Overall, time did not affect the odds of outcomes differently between immigrant and Italian mothers and most outcomes improved over time among all infants. None of the risk factors considered confounded the associations. Conclusion Our findings suggest that migrant status is a risk factor for adverse perinatal

Venice, Italy

NASA Image and Video Library

2002-09-24

Four hundred bridges cross the labyrinth of canals that form the 120 islands of Venice, situated in a saltwater lagoon between the mouths of the Po and Piave rivers in northeast Italy. All traffic in the city moves by boat. Venice is connected to the mainland, 4 kilometers (2.5 miles) away, by ferries as well as a causeway for road and rail traffic. The Grand Canal winds through the city for about 3 kilometers (about 2 miles), dividing it into two nearly equal sections. According to tradition, Venice was founded in 452, when the inhabitants of Aquileia, Padua, and several other northern Italian cities took refuge on the islands of the lagoon from the Teutonic tribes invading Italy at that time. This image was acquired on December 9, 2001 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER will image Earth for the next 6 years to map and monitor the changing surface of our planet. http://photojournal.jpl.nasa.gov/catalog/PIA03860

Turin, Italy 2006

NASA Image and Video Library

2014-02-06

City lights at night along the France-Italy border, Europe are featured in this image photographed by an Expedition 23 crew member on the International Space Station (ISS). The brightly lit metropolitan areas of Torino (Italy), Lyon, and Marseille (both in France) stand out amidst numerous smaller urban areas in this dramatic photograph. The image captures the night time appearance of the France-Italy border area between the mountainous Alps to the north (not shown) and the island of Corsica in the Ligurian Sea to the south (top). The full moon reflects brightly on the water surface and also illuminates the tops of low patchy clouds over the border (center). This image was taken by an ISS crew member at approximately 11:55 p.m. local time when the station was located over the France-Belgium border near Luxembourg. Crew members orbiting Earth frequently collect images that include sunglint, or sunlight that reflects off a water surface at such an angle that it travels directly back towards the observer. Sunglint typically lends a mirror-like appearance to the water surface. During clear sky conditions reflected light from the moon can produce the same effect (moon glint) as illustrated in this view. The observer was looking towards the southeast at an oblique viewing angle at the time the image was taken; in other words, looking outwards from the ISS, not straight down towards Earth. Credit: NASA NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Enterovirus D68-associated community-acquired pneumonia in children living in Milan, Italy.

PubMed

Esposito, Susanna; Zampiero, Alberto; Ruggiero, Luca; Madini, Barbara; Niesters, Hubert; Principi, Nicola

2015-07-01

An increasing number of children infected by enterovirus D68 (EV-D68) and affected by severe respiratory illness, muscle weakness and paralysis were described in the USA and Canada in 2014 OBJECTIVES: To investigate the potential involvement of EV-D68 in determining community-acquired pneumonia (CAP) in hospitalised children in order to acquire information concerning the clinical problems associated with EV-D68 in Italy. This prospective study of children hospitalised for CAP in the largest Pediatric Department in Milan, Italy, was carried out between 1 June and 31 December 2014. All of the children's admission nasopharyngeal swabs were investigated for the presence of EV-D68. One hundred and seventy-six children with radiographically confirmed CAP were hospitalised during the 7-month study period: 97 (55.1%) had enterovirus/rhinovirus-positive nasopharyngeal samples, including four (2.3%) positive for EV-D68. These four samples were collected between 9 and 21 October, a month in which 21 cases of CAP were recorded. Phylogenetic analysis showed that all of the sequences fell into clade B. The most severe case was diagnosed in a 14-year-old girl with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS syndrome), who died after 12 days of hospitalisation. EV-D68 was detected in few children with usually mild-to-moderate lower respiratory tract infection, although the disease lead to the death of a girl with a severe chronic underlying disease. Further studies capable of better defining the epidemiological, genetic and pathogenetic characteristics of the virus are required in order to be able to prepare appropriate preventive and therapeutic measures. Copyright © 2015 Elsevier B.V. All rights reserved.

Earthquake-induced ground failures in Italy from a reviewed database

NASA Astrophysics Data System (ADS)

Martino, S.; Prestininzi, A.; Romeo, R. W.

2013-05-01

A database (Italian acronym CEDIT) of earthquake-induced ground failures in Italy is presented, and the related content is analysed. The catalogue collects data regarding landslides, liquefaction, ground cracks, surface faulting and ground-level changes triggered by earthquakes of Mercalli intensity 8 or greater that occurred in the last millennium in Italy. As of January 2013, the CEDIT database has been available online for public use (URL: http://www.ceri.uniroma1.it/cn/index.do?id=230&page=55) and is presently hosted by the website of the Research Centre for Geological Risks (CERI) of the "Sapienza" University of Rome. Summary statistics of the database content indicate that 14% of the Italian municipalities have experienced at least one earthquake-induced ground failure and that landslides are the most common ground effects (approximately 45%), followed by ground cracks (32%) and liquefaction (18%). The relationships between ground effects and earthquake parameters such as seismic source energy (earthquake magnitude and epicentral intensity), local conditions (site intensity) and source-to-site distances are also analysed. The analysis indicates that liquefaction, surface faulting and ground-level changes are much more dependent on the earthquake source energy (i.e. magnitude) than landslides and ground cracks. In contrast, the latter effects are triggered at lower site intensities and greater epicentral distances than the other environmental effects.

Earthquake-induced ground failures in Italy from a reviewed database

NASA Astrophysics Data System (ADS)

Martino, S.; Prestininzi, A.; Romeo, R. W.

2014-04-01

A database (Italian acronym CEDIT) of earthquake-induced ground failures in Italy is presented, and the related content is analysed. The catalogue collects data regarding landslides, liquefaction, ground cracks, surface faulting and ground changes triggered by earthquakes of Mercalli epicentral intensity 8 or greater that occurred in the last millennium in Italy. As of January 2013, the CEDIT database has been available online for public use (http://www.ceri.uniroma1.it/cn/gis.jsp ) and is presently hosted by the website of the Research Centre for Geological Risks (CERI) of the Sapienza University of Rome. Summary statistics of the database content indicate that 14% of the Italian municipalities have experienced at least one earthquake-induced ground failure and that landslides are the most common ground effects (approximately 45%), followed by ground cracks (32%) and liquefaction (18%). The relationships between ground effects and earthquake parameters such as seismic source energy (earthquake magnitude and epicentral intensity), local conditions (site intensity) and source-to-site distances are also analysed. The analysis indicates that liquefaction, surface faulting and ground changes are much more dependent on the earthquake source energy (i.e. magnitude) than landslides and ground cracks. In contrast, the latter effects are triggered at lower site intensities and greater epicentral distances than the other environmental effects.

Reflections of a Lifelong Learner Teaching in Italy

ERIC Educational Resources Information Center

Kroth, Michael

2014-01-01

This article describes and summarizes the author's experience of teaching in Italy for three months and the impact it had on him and his learning. The author, at the age of 61, lived in Italy for three months and here he reflects on what he learned and how it relates to adult learning theory concepts.

Toscana Virus Epidemiology: From Italy to Beyond

PubMed Central

Cusi, Maria G; Savellini, Gianni G; Zanelli, Giacomo

2010-01-01

Toscana virus (TOSV) is an arthropod-borne virus which is transmitted to humans by Phlebotomus spp sandflies. Infection is the cause of brain injuries, such as aseptic meningitis and meningoencephalitis, in Italy mainly during the summer. More recently some unusual clinical manifestations due to TOSV with severe sequelae, such as ischemic complications and hydrocephalus, have been reported. TOSV represents an important emerging pathogen and its presence is being investigated in several European countries on the Mediterranean basin, including Italy, France, Spain, Portugal and Cyprus. Phylogenetic analysis has distinguished two genotypes of TOSV, A and B; the first is circulating mainly in Italy and the second in Spain, indicating a different geographic distribution possibly related to the vector. This distribution, evolving with the climate, globalization and habitat modification, has implications for the epidemiology of TOSV. PMID:20517492

Nardò Ring, Italy

NASA Image and Video Library

2008-04-08

The Nardò Ring is a striking visual feature from space, and astronauts have photographed it several times. The Ring is a race car test track in Italy. This image was acquired by NASA Terra satellite on August 17. 2007.

Suicidal ideation among surgeons in Italy and Sweden - a cross-sectional study.

PubMed

Wall, Maja; Schenck-Gustafsson, Karin; Minucci, Daria; Sendén, Marie Gustafsson; Løvseth, Lise Tevik; Fridner, Ann

2014-01-01

Suicidal ideation is more prevalent among physicians, compared to the population in general, but little is known about the factors behind surgeons' suicidal ideation. A surgeon's work environment can be competitive and characterised by degrading experiences, which could contribute to burnout, depression and even thoughts of suicide. Being a surgeon has been reported to be predictor for not seeking help when psychological distressed. The aim of the present study was to investigate to what extent surgeons in Italy and Sweden are affected by suicidal ideation, and how suicidal ideation can be associated with psychosocial work conditions. A cross-sectional study of surgeons was performed in Italy (N = 149) and Sweden (N = 272), where having suicidal ideation was the outcome variable. Work-related factors, such as harassment, depression and social support, were also measured. Suicidal ideation within the previous twelve months was affirmatively reported by 18% of the Italian surgeons, and by 12% of the Swedish surgeons in the present study. The strongest association with having recent suicidal ideation for both countries was being subjected to degrading experiences/harassment at work by a senior physician. Sickness presenteeism, exhaustion and disengagement were related to recent suicidal ideation among Italian surgeons, while role conflicts and sickness presenteeism were associated with recent suicidal ideation in the Swedish group. For both countries, regular meetings to discuss situations at work were found to be protective. A high percentage of surgeons at two university hospitals in Italy and Sweden reported suicidal ideation during the year before the investigation. This reflects a tough workload, including sickness presenteeism, harassment at work, exhaustion/disengagement and role conflicts. Regular meetings to discuss work situations might be protective.

Hepatitis E Virus Genotype 4 Outbreak, Italy, 2011

PubMed Central

Garbuglia, Anna R.; Scognamiglio, Paola; Petrosillo, Nicola; Mastroianni, Claudio Maria; Sordillo, Pasquale; Gentile, Daniele; La Scala, Patrizia; Girardi, Enrico

2013-01-01

During 2011, 5 persons in the area of Lazio, Italy were infected with a monophyletic strain of hepatitis E virus that showed high sequence homology with isolates from swine in China. Detection of this genotype in Italy parallels findings in other countries in Europe, signaling the possible spread of strains new to Western countries. PMID:23260079

Malaria in Italy - Migrants Are Not the Cause.

PubMed

Benelli, Giovanni; Pombi, Marco; Otranto, Domenico

2018-05-01

Recently, five cases of malaria were reported in Italy. These people had not travelled abroad, prompting some media and political organizations to fuel a climate of fear by connecting the cases with migrants coming into the country. Here, we discuss scientific data highlighting the limited risk of malaria reintroduction in Italy. Copyright © 2018 Elsevier Ltd. All rights reserved.

Rainfall thresholds for possible landslide occurrence in Italy

NASA Astrophysics Data System (ADS)

Peruccacci, Silvia; Brunetti, Maria Teresa; Gariano, Stefano Luigi; Melillo, Massimo; Rossi, Mauro; Guzzetti, Fausto

2017-08-01

The large physiographic variability and the abundance of landslide and rainfall data make Italy an ideal site to investigate variations in the rainfall conditions that can result in rainfall-induced landslides. We used landslide information obtained from multiple sources and rainfall data captured by 2228 rain gauges to build a catalogue of 2309 rainfall events with - mostly shallow - landslides in Italy between January 1996 and February 2014. For each rainfall event with landslides, we reconstructed the rainfall history that presumably caused the slope failure, and we determined the corresponding rainfall duration D (in hours) and cumulated event rainfall E (in mm). Adopting a power law threshold model, we determined cumulated event rainfall-rainfall duration (ED) thresholds, at 5% exceedance probability, and their uncertainty. We defined a new national threshold for Italy, and 26 regional thresholds for environmental subdivisions based on topography, lithology, land-use, land cover, climate, and meteorology, and we used the thresholds to study the variations of the rainfall conditions that can result in landslides in different environments, in Italy. We found that the national and the environmental thresholds cover a small part of the possible DE domain. The finding supports the use of empirical rainfall thresholds for landslide forecasting in Italy, but poses an empirical limitation to the possibility of defining thresholds for small geographical areas. We observed differences between some of the thresholds. With increasing mean annual precipitation (MAP), the thresholds become higher and steeper, indicating that more rainfall is needed to trigger landslides where the MAP is high than where it is low. This suggests that the landscape adjusts to the regional meteorological conditions. We also observed that the thresholds are higher for stronger rocks, and that forested areas require more rainfall than agricultural areas to initiate landslides. Finally, we

Concentrating Solar Power Projects in Italy | Concentrating Solar Power |

Science.gov Websites

;alphabetical by project name. You can browse a project profile by clicking on the project name. Archimede ASE NREL Italy Concentrating solar power (CSP) projects in Italy are listed belowâ€"

Sensitization to Rubber Accelerators in Northeastern Italy: The Triveneto Patch Test Database.

PubMed

Buttazzo, Silvia; Prodi, Andrea; Fortina, Anna Belloni; Corradin, Maria Teresa; Larese Filon, Francesca

2016-01-01

Natural and synthetic rubbers containing rubber accelerators are well-known causes of occupational skin disease. Allergic contact dermatitis caused by rubber gloves is frequent and has almost exclusively been attributed to contact sensitization to accelerators. This study aimed to evaluate the frequency of rubber accelerators sensitization in the population living in northeastern Italy, to find time trend and a correlation with occupations, and to investigate co-sensitization between rubber accelerators. A population of 23,774 subjects was patch tested in 6 cities in northeastern Italy in the years 1996 to 2012 using carba mix 3%, thiuram mix 1%, benzothiazole (MBT) mix 1%, and isopropyl phenyl paraphenylamine diamine (IPPD) mix 0.6%. The overall frequency of carbamates, MBT, thiurams, and IPPD mix sensitization was 3.4%, 0.65%, 1.75%, and 0.83%, respectively. On a logistic regression analysis (control group: white-collar workers), we found a statistically significant association to carbamates (odds ratio [OR], 1.3; 95% confidence interval [CI], 1.03-1.7) and thiurams (OR, 1.6; 95% CI, 1.1-2.3) for health care workers. Thiuram sensitivity was also significantly associated with dermatitis in maids and restaurant workers (OR, 2.2; 95% CI, 1.4-3.6), hairdressers (OR, 3.6; 95% CI, 1.8-7.1), shop assistants (OR, 2.9; 95% CI, 1.2-6.8), construction workers (OR, 2.7; 95% CI, 1.7-4.1), mechanics (OR, 2.1; 95% CI, 1.3-3.4), and professional drivers (OR, 2.6; 95% CI, 1.2-5.9). In conclusion, our results demonstrated that rubber accelerators have an important role in allergic contact dermatitis in the northeast of Italy and their sensitization is associated significantly with occupations that wear gloves or use chemical substances. Between rubber accelerators tested, carbamates sensitization is prevalent and increasing during considered years.

SELF and VLF electromagnetic emissions that preceded the M6.2 Central Italy earthquake occurred on August 24, 2016

NASA Astrophysics Data System (ADS)

Cataldi, Daniele; Cataldi, Gabriele; Straser, Valentino

2017-04-01

On August 24, 2016 at 01:36:32 UTC a destructive earthquake hit Central Italy with a magnitude of M6.2. The authors of this study have recorded some electromagnetic signals that have preceded this strong earthquake. These signals were recorded through two electromagnetic monitoring stations realized by Gabriele Cataldi and Daniele Cataldi, located near the town of Albano Laziale (Rome, Italy) and near the city of Lariano (Rome, Italy) and can monitor the radio spectrum 24h7 between 0.001 Hz and 96 kHz (SELF-LF band). The electromagnetic monitoring allowed to identify two interesting types of electromagnetic anomalies: the first electromagnetic anomaly was recorded on August 18, 2016 between 02:47 UTC and 06:21 UTC, in the VLF band prevalently between 18kHz and 26kHz; the second electromagnetic anomaly was registered between 08:00 UTC on August 23, 2016 and 05:00 UTC on August 24, 2016, prevalently between 0.01 and 0.7Hz: the most intense signals were recorded at 08:50 UTC on August 23, 2016 and approximately 1 hour before the strong earthquake. The Earth's electromagnetic background monitoring in the SELF-VLF band (0Hz

Proceedings of the Annual International Conference of the Association for the Education of Teachers in Science (Costa Mesa, California, January 18-21, 2001).

ERIC Educational Resources Information Center

Rubba, Peter A., Ed.; Rye, James A., Ed.; DiBiase, Warren J., Ed.; Crawford, Barbara A., Ed.

This document contains the proceedings of the 2001 Annual International Conference of the Association for the Education of Teachers in Science which was held in Costa Mesa, California, January 18-21, 2001. Papers include: (1) "An Elementary Preservice Teacher's Search for Solutions about the Evolution-Divine Creation Question: The Story of Tracy"…

A review of insect parasitoids associated with Lobesia botrana (Denis & Schiffermüller, 1775) in Italy. 1. DipteraTachinidae and HymenopteraBraconidae (Lepidoptera, Tortricidae).

PubMed

Scaramozzino, Pier Luigi; Loni, Augusto; Lucchi, Andrea

2017-01-01

This paper is aimed to summarize the information available on the parasitoid complex of the European Grapevine Moth (EGVM), Lobesia botrana (Denis & Schiffermüller, 1775) (Lepidoptera Tortricidae) in Italy. The list is the result of the consultation of a vast bibliography published in Italy for almost two hundred years, from 1828 to date. This allowed the clarification and correction of misunderstandings and mistakes on the taxonomic position of each species listed. In Italy the complex of parasitoids detected on EGVM includes approximately 90 species belonging to ten families of Hymenoptera (Braconidae, Ichneumonidae, Chalcididae, Eulophidae, Eupelmidae, Eurytomidae, Pteromalidae, Torymidae, Trichogrammatidae, and Bethylidae) and one family of Diptera (Tachinidae). This paper deals with EGVM parasitoids of the families Tachinidae (Diptera) and Braconidae (Hymenoptera). Only two species of Tachinidae are associated to EGVM larvae in Italy, Actia pilipennis (Fallen) and Phytomyptera nigrina (Meigen), whereas the record of Eurysthaea scutellaris (Robineau-Desvoidy) is doubtful. Moreover, 21 species of Braconidae are reported to live on EGVM, but, unfortunately, eight of them were identified only at generic level. Bracon mellitor Say has been incorrectly listed among the parasitoids of Lobesia botrana . Records concerning Ascogaster rufidens Wesmael, Meteorus sp., Microgaster rufipes Nees, and Microplitis tuberculifer (Wesmael) are uncertain.

A review of insect parasitoids associated with Lobesia botrana (Denis & Schiffermüller, 1775) in Italy. 1. Diptera Tachinidae and Hymenoptera Braconidae (Lepidoptera, Tortricidae)

PubMed Central

Scaramozzino, Pier Luigi; Loni, Augusto; Lucchi, Andrea

2017-01-01

Abstract This paper is aimed to summarize the information available on the parasitoid complex of the European Grapevine Moth (EGVM), Lobesia botrana (Denis & Schiffermüller, 1775) (Lepidoptera Tortricidae) in Italy. The list is the result of the consultation of a vast bibliography published in Italy for almost two hundred years, from 1828 to date. This allowed the clarification and correction of misunderstandings and mistakes on the taxonomic position of each species listed. In Italy the complex of parasitoids detected on EGVM includes approximately 90 species belonging to ten families of Hymenoptera (Braconidae, Ichneumonidae, Chalcididae, Eulophidae, Eupelmidae, Eurytomidae, Pteromalidae, Torymidae, Trichogrammatidae, and Bethylidae) and one family of Diptera (Tachinidae). This paper deals with EGVM parasitoids of the families Tachinidae (Diptera) and Braconidae (Hymenoptera). Only two species of Tachinidae are associated to EGVM larvae in Italy, Actia pilipennis (Fallen) and Phytomyptera nigrina (Meigen), whereas the record of Eurysthaea scutellaris (Robineau-Desvoidy) is doubtful. Moreover, 21 species of Braconidae are reported to live on EGVM, but, unfortunately, eight of them were identified only at generic level. Bracon mellitor Say has been incorrectly listed among the parasitoids of Lobesia botrana. Records concerning Ascogaster rufidens Wesmael, Meteorus sp., Microgaster rufipes Nees, and Microplitis tuberculifer (Wesmael) are uncertain. PMID:28325964

The disease burden of human cystic echinococcosis based on HDRs from 2001 to 2014 in Italy

PubMed Central

Brundu, Diego; Stegel, Giovanni; Loi, Federica; Rolesu, Sandro; Masu, Gabriella; Ledda, Salvatore; Masala, Giovanna

2017-01-01

Background Cystic echinococcosis (CE) is an important neglected zoonotic parasitic infection belonging to the subgroup of seven Neglected Zoonotic Disease (NZDs) included in the World Health Organization’s official list of 18 Neglected Tropical Diseases (NTDs). CE causes serious global human health concerns and leads to significant economic losses arising from the costs of medical treatment, morbidity, life impairments and fatality rates in human cases. Moreover, CE is endemic in several Italian Regions. The aim of this study is to perform a detailed analysis of the economic burden of hospitalization and treatment costs and to estimate the Disability Adjusted Life Years (DALYs) of CE in Italy. Methods and findings In the period from 2001 to 2014, the direct costs of 21,050 Hospital Discharge Records (HDRs) belonging to 12,619 patients with at least one CE-related diagnosis codes were analyzed in order to quantify the economic burden of CE. CE cases average per annum are 901 (min—max = 480–1,583). Direct costs include expenses for hospitalizations, medical and surgical treatment incurred by public and private hospitals and were computed on an individual basis according to Italian Health Ministry legislation. Moreover, we estimated the DALYs for each patient. The Italian financial burden of CE is around € 53 million; the national average economic burden per annum is around € 4 million; the DALYs of the population from 2001 to 2014 are 223.35 annually and 5.26 DALYs per 105 inhabitants. Conclusion In Italy, human CE is responsible for significant economic losses in the public health sector. In humans, costs associated with CE have been shown to have a great impact on affected individuals, their families and the community as a whole. This study could be used as a tool to prioritize and make decisions with regard to a surveillance system for this largely preventable yet neglected disease. It demonstrates the need of implementing a CE control program aimed at

Italy’s Carabinieri and Contemporary Security Challenges

DTIC Science & Technology

2017-12-01

the meantime, organized crime in Italy has grown to epic proportions, encompassing money laundering, counterfeiting, corruption, and drug trafficking...arrests.93 Organized crime involves international activities, including drug and human trafficking, illegal weapons, and money laundering. The...decades developed broad areas of cooperation, such as being trade partners. According to Nadezhda Arbatova, Italy supports “a visa- free travel regime

Active deformation and seismicity in the Southern Alps (Italy): The Montello hill as a case study

NASA Astrophysics Data System (ADS)

Danesi, Stefania; Pondrelli, Silvia; Salimbeni, Simone; Cavaliere, Adriano; Serpelloni, Enrico; Danecek, Peter; Lovati, Sara; Massa, Marco

2015-06-01

The Montello anticline is a morphotectonic feature of the east pede-mountain of the South Alpine Chain in northern Italy, which lies ca. 40 km northwest of Venice, Italy. The purpose of this study is to characterize the present-day crustal deformation and seismotectonics of the Montello area through multi-parametric geophysical observations. We used new data obtained from the installation of a temporary network of 12 seismic stations and 6 GPS sites. The GPS observations indicate that there is ~ 1 mm/yr shortening across the Montello thrust. Sites located north of the Montello thrust front deviate from the ~ NNW-ward Adria-Eurasia convergence direction, as they are constrained by a relative rotation pole in northwestern Italy that has a NNE-ward motion trend. Over 18 months, seismographic recordings allowed us to locate 142 local seismic events with Ml 0.5-3.5 with good reliability (rms < 0.5). After cross-correlation analysis, we classified 42 of these events into six clusters, with cross-correlation thresholds > 0.80. The source focal solutions indicate that: (i) there is thrusting seismic activity on the basal, sub-horizontal, portion of the Montello structure; and (ii) strike-slip source kinematics prevail on the western edge of the Montello hill. Our observations on the source mechanisms and the measured crustal deformation confirm that the Montello thrust is tectonically active.

[Aedes albopictus in Italy: an underestimated health problem].

PubMed

Romi, R

2001-01-01

Since 1990, Ae. albopictus has spread in 9 regions and 30 provinces of the country. This species was introduced in Italy in shipments of scrap tires form the USA. In Italy, Ae. albopictus is the major biting pest throughout much of its range and, although there is no evidence that this mosquito is the vector of human disease in the country, the species might be involved in the transmission of some arboviruses which have been reported in the Mediterranean Basin. Aim of this paper is to provide an update on the distribution of Ae. albopictus in Italy and to renew the interest in a problem frequently underestimated. Public health implications after a ten-year presence of the species are also discussed.

First-trimester contingent screening for trisomies 21, 18 and 13 by biomarkers and maternal blood cell-free DNA testing.

PubMed

Nicolaides, K H; Syngelaki, A; Poon, L C; Gil, M M; Wright, D

2014-01-01

To examine potential performance of screening for trisomies by cell-free (cf) DNA testing in maternal blood contingent on results of first-line testing by combinations of fetal translucency thickness (NT), fetal heart rate (FHR), ductus venosus pulsatility index (DV PIV), and serum-free β-human chorionic gonadotropin (β-hCG), pregnancy-associated plasma protein-A (PAPP-A), placental growth factor (PLGF) and α-fetoprotein (AFP). Performance was estimated for firstly, screening by cfDNA in all pregnancies and secondly, cfDNA testing contingent on results of first-line testing by combinations of ultrasound and biochemical markers. In first-line screening by cfDNA testing, the detection rate for trisomy 21 and trisomies 18 or 13 would be 99 and 96%, respectively, after invasive testing in 1% of the population. In contingent screening, a detection rate of 98% for trisomy 21 and 96% for trisomy 18 or 13, at an invasive testing rate of 0.7%, can be achieved by carrying out cfDNA testing in about 35, 20 and 11% of cases identified by first-line screening with the combined test alone (age, NT, FHR, β-hCG, PAPP-A), the combined test plus PLGF and AFP and the combined test plus PLGF, AFP and DV PIV, respectively. Effective first-trimester screening for trisomies can be achieved by contingent screening incorporating biomarkers and cfDNA testing. © 2013 S. Karger AG, Basel.

Lake Geneva, France/Italy/Switzerland

NASA Image and Video Library

1994-09-30

STS068-243-076 (30 September-11 October 1994) --- Parts of the Swiss Cantons of Vaud and Valois, the French province of Chablis and parts of northwestern Italy are seen in this widely stretching image photographed from the Space Shuttle Endeavour. Pennine Alps, said to have been created 50 million years ago, have been reshaped by glaciers during Pleistocene. The glaciers created the wide valley of the Rhone River by scourting a pre-existing seam. The fertile Swiss Plateau runs northwest from the shore of Lake Geneva and is visible in lower left. The Franco-Swiss border is located in the center of the lake and follows a mountain divide east of Rhone Valley. Italy lies south of the Rhone.

Personal Identity in Italy

ERIC Educational Resources Information Center

Crocetti, Elisabetta; Rabaglietti, Emanuela; Sica, Luigia Simona

2012-01-01

This chapter discusses specifics of identity formation in Italian adolescents and emerging adults. We review consistent evidence illustrating that, in Italy, a progressive deferral of transition to adulthood strongly impacts youth identity development by stimulating identity exploration and postponement of identity commitments. We also consider…

Italy SimSmoke: the effect of tobacco control policies on smoking prevalence and smoking attributable deaths in Italy

PubMed Central

2012-01-01

Background While Italy has implemented some tobacco control policies over the last few decades, which resulted in a decreased smoking prevalence, there is still considerable scope to strengthen tobacco control policies consistent with the World Health Organization (WHO) policy guidelines. The present study aims to evaluate the effect of past and project the effect of future tobacco control policies on smoking prevalence and associated premature mortality in Italy. Methods To assess, individually and in combination, the effect of seven types of policies, we used the SimSmoke simulation model of tobacco control policy. The model uses population, smoking rates and tobacco control policy data for Italy. Results Significant reductions of smoking prevalence and premature mortality can be achieved through tobacco price increases, high intensity media campaigns, comprehensive cessation treatment program, strong health warnings, stricter smoke-free air regulations and advertising bans, and youth access laws. With a comprehensive approach, the smoking prevalence can be decreased by as much as 12% soon after the policies are in place, increasing to a 30% reduction in the next twenty years and a 34% reduction by 30 years in 2040. Without effective tobacco control policies, a total of almost 300 thousand lives will be prematurely lost due to smoking by the year 2040. Conclusion Besides presenting the benefits of a comprehensive tobacco control strategy, the model helps identify information gaps in surveillance and evaluation schemes that will promote the effectiveness of future tobacco control policy in Italy. PMID:22931428

Mazzini and the Radical Movement in Nineteenth-Century Italy.

ERIC Educational Resources Information Center

Noether, Emiliana P.

1988-01-01

Discusses the origins of radicalism in Italy, specifically the emergence in 1831 of Giuseppe Mazzini as the advocate of Italian nationalism and radicalism. Examines Mazzini's role in Italy and among European revolutionaries, concluding that his legacy led to the establishment of the Italian republic in the twentieth century. (GEA)

Young People and Alcohol in Italy: An Evolving Relationship

ERIC Educational Resources Information Center

Beccaria, Franca; Prina, Franco

2010-01-01

In Italy, commonly held opinions and interpretations about the relationship between young people and alcohol are often expressed as generalizations and approximations. In order to further understanding of the relationship between young people and alcohol in contemporary Italy, we have gathered, compared and discussed all the available data, both…

Historical hydrology and database on flood events (Apulia, southern Italy)

NASA Astrophysics Data System (ADS)

Lonigro, Teresa; Basso, Alessia; Gentile, Francesco; Polemio, Maurizio

2014-05-01

. More details on previous results of this research activity were recently published (Polemio, 2010; Basso et al., 2012; Lonigro et al., 2013) References Basso A., Lonigro T. and Polemio M. (2012) "The improvement of historical database on damaging hydrogeological events in the case of Apulia (Southern Italy)". Rendiconti online della Società Geologica Italiana, 21: 379-380; Lonigro T., Basso A. and Polemio M. (2013) "Historical database on damaging hydrogeological events in Apulia region (Southern Italy)". Rendiconti online della Società Geologica Italiana, 24: 196-198; Polemio M. (2010) "Historical floods and a recent extreme rainfall event in the Murgia karstic environment (Southern Italy)". Zeitschrift für Geomorphologie, 54(2): 195-219.

Implementation of cardiovascular secondary prevention guidelines in clinical practice: a nationwide survey in Italy.

PubMed

Perrone-Filardi, P; Poli, A; Ambrosio, G; Proto, C; Chimini, C; Chiariello, M

2012-02-01

To report the implementation of cardiovascular secondary prevention guidelines following a cardiovascular event in Italy. Data were collected from 878 consecutive patients, who had suffered a cardiovascular event requiring hospitalisation in the preceding 12-24 months and who presented at 49 outpatient clinics across Italy. Cardiovascular risk markers were assessed through clinical examination, interview and reviewing of patients' charts; in addition, we collected information on changes in prevalence of selected risk factors that occurred since the time of index event. At the time of evaluation, increased body mass index (BMI) was observed in 35% of patients, with 20% being obese; 26% had diabetes and 21% uncontrolled hypertension. Although 91% of patients were on statins, no measurement of low-density lipoprotein (LDL)-cholesterol was available in the previous 6 months in 27% of patients and 16% had no knowledge of any lipid parameter in the same period. In the remaining patients, LDL was <100 mg dl(-1) in 57% and <70 mg dl(-1) in 20% of them. From the time of index event to interview, prevalence of uncontrolled hypertension remained stable, from 24% to 21% of patients; according to the patients' self-reporting, smoking had declined from 32% to 13% of patients and physical inactivity from 43% to 33% of patients. This survey shows, in a large national cohort, a suboptimal implementation of lifestyle changes and inadequate lipid control in patients at high cardiovascular risk after a cardiovascular event. Reinforcement of patients and physicians, implementation and adherence to guidelines is needed to reduce the burden of cardiovascular disease. Copyright © 2010 Elsevier B.V. All rights reserved.

78 FR 55095 - Certain Pasta From Italy and Turkey

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-09

...)] Certain Pasta From Italy and Turkey Determinations On the basis of the record \\1\\ developed in the subject... countervailing and antidumping duty orders on certain pasta from Italy and Turkey would be likely to lead to... respect to imports of certain pasta from Turkey. Background The Commission instituted these reviews on...

OGS improvements in 2012 in running the Northeastern Italy Seismic Network: the Ferrara VBB borehole seismic station

NASA Astrophysics Data System (ADS)

Pesaresi, Damiano; Romanelli, Marco; Barnaba, Carla; Bragato, Pier Luigi; Durì, Giorgio

2013-04-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Center) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 17 very sensitive broad band and 18 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data center in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of Northeastern Italy. The southwestern edge of the OGS seismic network stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. OGS ha already experience in running a local seismic network in high noise conditions making use of borehole installations in the case of the micro-seismicity monitoring of a local gas storage site for a private company. Following the ML=5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on May 20, 2012 at 02:03:53 UTC, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate the seismic response at the site. We will describe improvements in running the Northeastern Italy Seismic Network, including details of the Ferrara VBB

Impact of the economic crisis on health-related behaviors in Italy.

PubMed

Mattei, Giorgio; De Vogli, Roberto; Ferrari, Silvia; Pingani, Luca; Rigatelli, Marco; Galeazzi, Gian Maria

2017-11-01

Evidence exists supporting the impact of the Great Recession on health-related behaviors internationally, though few studies are available concerning the Italian population. To assess the impact of the late 2000s economic crisis on health-related behaviors linked to population mental health in Italy. Descriptive study. Health indicators came from the Italian Institute of Statistics database (years 2000-2015). Statistics performed by means of linear regression models. Increased smokers (β = 1.68, p = .03), heavy smokers, that is, people smoking 11-20 cigarettes per day (β = 2.18, p = .04) or more than 20 cigarettes per day (β = 1.04, p < .01) and mean number of smoked cigarettes per day (β = 0.56, p = .02) were noticeable. Also, prevalence of overweight increased (β = 0.91, p = .04), while the Italian families' expenditure for alcoholic beverages decreased (β = -812.80, p = .01). Alcohol consumption decreased (β = -0.60, p < .01), especially in men (β = -0.95, p < .01); binge drinking increased in years 2009-2010. No change was noticeable in the diet indicators collected. The economic crisis may have increased smoking, overweight and binge drinking in Italy (though data on the latter phenomenon are not conclusive), and reduced overall alcohol consumption.

Survey on the treatment of non-small-cell lung cancer in Italy.

PubMed

Alexanian, A; Torri, V

2000-07-01

The results of the Italian part of an international survey on therapeutic preferences and opinions about prognosis of patients affected by non-small-cell lung cancer (NSCLC) are shown. The investigation was conducted by the means of a postal questionnaire aiming to gather information on preferences about treatment and beliefs about survival of three hypothetical patients affected by NSCLC in different stages (T2N1M0, T2N3M0, M1); three sources of Italian physicians potentially treating patients affected by NSCLC were the target population: participants in the Adjuvant Lung Project Italy (Alpi) trial, a 20% random sample of the Italian Medical Oncology Association (AIOM) and representatives of almost all the pneumology wards in Italy. Overall, there were 287 evaluable responses, 89% of respondents were males, mean age was 46 years, years from graduation 21 and charge of patients per clinician 82. The most important result is the wide variation of answers both about therapy and prognosis. Expectations about size of prognosis improvement with a new chemotherapy seem to be excessive. The results are discussed in relation to the twin surveys of Canada and England and Wales and to the meta-analyses on the efficacy of chemotherapy as an adjunct to primary treatment and on postoperative radiotherapy in non-small-cell lung cancer.

Tetanus immunity in construction workers in Italy.

PubMed

Rapisarda, V; Bracci, M; Nunnari, G; Ferrante, M; Ledda, C

2014-04-01

Tetanus is a serious vaccine-preventable disease that remains a significant health risk in certain occupations. Since 2006, Italy has reported the highest number of cases in Europe. Some professions, such as construction workers, are more exposed to tetanus. To evaluate tetanus immunity status and associated factors in construction workers in Italy. A cross-sectional study of construction workers attending for periodic occupational health surveillance at one site in Italy between September 2011 and January 2013. Serum tetanus antitoxin levels were measured and analysed according to demographic and clinical variables. All 5275 workers attending for health surveillance between September 2011 and January 2013 agreed to participate. Protective tetanus antitoxin levels (>0.1 IU/ml) were found in 4116 workers (78%). Multivariate logistic regression analysis suggested that the following risk factors were significantly associated with inadequate immunization status: older age (age >58 years, odds ratio [OR] 1.78, 95% confidence intervals [CIs] 1.76-1.84), poor education (no formal education: OR 3.74, 95% CI: 3.69-3.78), unskilled work tasks (OR 2.71, 95% CI: 2.67-2.77) and country of origin (Egypt: OR 1.72, 95% CI: 1.67-1.77; Morocco: OR 1.69, 95% CI: 1.62-1.76). In this study, a significant proportion of construction workers in Italy were not adequately immunized against tetanus, as required by Italian law. Occupational health professionals should promote and implement vaccination campaigns, especially among migrant workers, for public health and legal reasons.

Proceedings of the symposium on research and management of annosus root disease (Heterobasidion annosum) in western North America; April 18-21, 1989; Monterey, CA.

Treesearch

William J. Otrosina; Robert F. Scharpf

1989-01-01

The proceedings is a collection of papers presented at the Symposium on Research and Management of Annosus Root Disease (Heterobasidion annosum) in Western North America held in Monterey, California, April 18-21, 1989. As the first symposium dealing with this subject in the western United States, the papers presented address current research and...

Quaternary fluvial terraces of the Tiber Valley: geochronologic and geometric constraints on the back-arc magmatism-related uplift in central Italy.

PubMed

Marra, Fabrizio; Florindo, Fabio; Petronio, Carmelo

2017-05-31

Through a geomorphological study relying on statistically assessed classes of hilltop elevations, we reconstruct a suite of paleo-surfaces along the Tiber River Valley north of Rome that we identify as fluvial terraces formed by interplay between global sea-level fluctuations and regional upift. Using biostratigraphic constraints provided by marine through continental deposits of Santernian age, we recognize the oldest terrace in this area, corresponding to an early coastal plain of late Santernian-Emilian age. By assuming the simple chronological principle of a staircase geometry we correlate the sea-level highstands of MIS 21 through MIS 5 with the lowest eight paleo-surfaces. By plotting against time the cumulated terrace elevations and the average elevation of the Santernian coastline in the investigated area, we detect rates of uplift during the last 1.8 Ma. Two major pulses of uplift are recognized 0.86 through 0.5 Ma, and 0.25 Ma through the Present, which are interpreted as driven by the subduction process and uprising of metasomatized magma bodies on the Tyrrhenian Sea Margin of central Italy, superimposied on a smaller isostatic component of uplift.

From Rome to Como: 20 years of active research on carbon-based electrodes for lithium batteries at INP-Grenoble

NASA Astrophysics Data System (ADS)

Yazami, Rachid

This paper reviews the main areas of research performed at different Laboratories of the Institut National Polytechnique de Grenoble (INPG) over the past 20 years, specifically on cabonaceous materials for electrode applications in lithium batteries. The most significant event was the discovery in the early 1980s of reversible lithium intercalation into graphite in polymer electrolytes, which led to the use of this material in today's lithium-ion batteries. Important work was also carried out on positive electrode for primary and secondary batteries, especially graphite oxide and graphite fluoride. Most of these results were presented at the 10 IMLB series Symposia, which started in Rome in 1982 and were back to Como, Italy, in 2000.

Campania Preventability Assessment Committee (Italy): A Focus on the Preventability of Non-steroidal Anti-inflammatory Drugs' Adverse Drug Reactions.

PubMed

Sessa, Maurizio; Sportiello, Liberata; Mascolo, Annamaria; Scavone, Cristina; Gallipoli, Silvia; di Mauro, Gabriella; Cimmaruta, Daniela; Rafaniello, Concetta; Capuano, Annalisa

2017-01-01

Purpose: This study aims to investigate preventability criteria of adverse drug reactions (ADRs) involving non-steroidal anti-inflammatory drugs (NSAIDs) by analyzing individual case safety reports (ICSRs) sent through Campania region (Italy) spontaneous reporting system from July 2012 to October 2016. Methods: For all the ICSRs that reported NSAIDs as suspected drug, a trained multidisciplinary team of Campania Pharmacovigilance Regional Centre composed of clinical pharmacologists and pharmacists with pluriannual experience in Pharmacovigilance assessed preventability by using the P-method. Results: In all 19,039 ICSRs were sent to Campania Pharmacovigilance Regional Centre, of which 550 reported NSAIDs as suspected drug. In total, 94 cases (17.1%) out of 550 ICSRs were preventable. In the 94 preventable cases, 201 critical criteria were detected of which 182/201 (90.5%) related to healthcare professionals' practices, 0/201 (0.0%) to drug quality, and 19/201 (9.5%) to patient behavior. The most detected critical criteria were the necessary medication not given (52/182; 28.6%), labeled drug-drug interaction (36/182; 19.7%), incorrect drug administration duration (31/182; 16.9%), wrong indication (26/182; 14.2%), therapeutic duplication (18/182; 10.0%), and documented hypersensitivity to administered drug or drug class (10/182; 5.6%). In seventeen (18.1%) preventable cases, there were 19 critical criteria involving non-compliance (15/19 critical criteria; 78.9%) and self-medication with the non-over-the-counter drugs (4/19 critical criteria; 21.1%). In all, 17 out 94 (18.1%) preventable cases involved over-the-counter drugs. Conclusion: A call for action for Campania Pharmacovigilance Regional Centre is necessary in order to promote initiatives to increase the awareness of healthcare professionals and citizens on the risk associated with inappropriate use of NSAIDs.

Campania Preventability Assessment Committee (Italy): A Focus on the Preventability of Non-steroidal Anti-inflammatory Drugs' Adverse Drug Reactions

PubMed Central

Sessa, Maurizio; Sportiello, Liberata; Mascolo, Annamaria; Scavone, Cristina; Gallipoli, Silvia; di Mauro, Gabriella; Cimmaruta, Daniela; Rafaniello, Concetta; Capuano, Annalisa

2017-01-01

Purpose: This study aims to investigate preventability criteria of adverse drug reactions (ADRs) involving non-steroidal anti-inflammatory drugs (NSAIDs) by analyzing individual case safety reports (ICSRs) sent through Campania region (Italy) spontaneous reporting system from July 2012 to October 2016. Methods: For all the ICSRs that reported NSAIDs as suspected drug, a trained multidisciplinary team of Campania Pharmacovigilance Regional Centre composed of clinical pharmacologists and pharmacists with pluriannual experience in Pharmacovigilance assessed preventability by using the P-method. Results: In all 19,039 ICSRs were sent to Campania Pharmacovigilance Regional Centre, of which 550 reported NSAIDs as suspected drug. In total, 94 cases (17.1%) out of 550 ICSRs were preventable. In the 94 preventable cases, 201 critical criteria were detected of which 182/201 (90.5%) related to healthcare professionals' practices, 0/201 (0.0%) to drug quality, and 19/201 (9.5%) to patient behavior. The most detected critical criteria were the necessary medication not given (52/182; 28.6%), labeled drug–drug interaction (36/182; 19.7%), incorrect drug administration duration (31/182; 16.9%), wrong indication (26/182; 14.2%), therapeutic duplication (18/182; 10.0%), and documented hypersensitivity to administered drug or drug class (10/182; 5.6%). In seventeen (18.1%) preventable cases, there were 19 critical criteria involving non-compliance (15/19 critical criteria; 78.9%) and self-medication with the non-over-the-counter drugs (4/19 critical criteria; 21.1%). In all, 17 out 94 (18.1%) preventable cases involved over-the-counter drugs. Conclusion: A call for action for Campania Pharmacovigilance Regional Centre is necessary in order to promote initiatives to increase the awareness of healthcare professionals and citizens on the risk associated with inappropriate use of NSAIDs. PMID:28603499

Italy INAF Data Center Report

NASA Technical Reports Server (NTRS)

Negusini, M.; Sarti, P.

2013-01-01

This report summarizes the activities of the Italian INAF VLBI Data Center. Our Data Center is located in Bologna, Italy and belongs to the Institute of Radioastronomy, which is part of the National Institute of Astrophysics.

John Ray in Italy: lost manuscripts rediscovered

PubMed Central

Hunter, Michael

2014-01-01

This paper discloses the content of two manuscripts of John Ray that have hitherto been unknown to Ray scholars. The manuscripts survive in the Hampshire Record Office, having descended through the Prideaux-Brune family. They record information about Ray's tour of Italy in the 1660s that does not appear in his Observations … made in a journey through … the Low-countries, Germany, Italy and France (1673), including a visit to the museum of Athanasius Kircher in Rome, and provide clues concerning the composition of Ray's 1673 book. PMID:24921104

Global alliance against chronic respiratory diseases in Italy (GARD-Italy): strategy and activities.

PubMed

Laurendi, Giovanna; Mele, Sonia; Centanni, Stefano; Donner, Claudio F; Falcone, Franco; Frateiacci, Sandra; Lazzeri, Marta; Mangiacavallo, Antonino; Indinnimeo, Luciana; Viegi, Giovanni; Pisanti, Paola; Filippetti, Giuseppe

2012-01-01

The steady increase in incidence of chronic respiratory disease (CRD) now constitutes a serious public health problem. CRDs are often underdiagnosed and many patients are not diagnosed until the CRD is too severe to prevent normal daily activities. The prevention of CRDs and reducing their social and individual impacts means modifying environmental and social factors and improving diagnosis and treatment. Prevention of risk factors (tobacco smoke, allergens, occupational agents, indoor/outdoor air pollution) will significantly impact on morbidity and mortality. The Italian Ministry of Health (MoH) has made respiratory disease prevention a top priority and is implementing a comprehensive strategy with policies against tobacco smoking, indoor/outdoor pollution, obesity, and communicable diseases. Presently these actions are not well coordinated. The Global Alliance against Chronic Respiratory Diseases (GARD), set up by the World Health Organization, envisages national bodies; the GARD initiative in Italy, launched 11/6/2009, represents a great opportunity for the MoH. Its main objective is to promote the development of a coordinated CRD program in Italy. Effective prevention implies setting up a health policy with the support of healthcare professionals and citizen associations at national, regional, and district levels. What is required is a true inter-institutional synergy: respiratory diseases prevention cannot and should not be the responsibility of doctors alone, but must involve politicians/policymakers, as well as the media, local institutions, and schools, etc. GARD could be a significant experience and a great opportunity for Italy to share the GARD vision of a world where all people can breathe freely. Copyright © 2011 Elsevier Ltd. All rights reserved.

[Social cooperatives in Italy].

PubMed

Villotti, P; Zaniboni, S; Fraccaroli, F

2014-06-01

This paper describes the role of social cooperatives in Italy as a type of economic, non-profit organization and their role in contributing to the economic and social growth of the country. The purpose of this paper is to learn more about the experience of the Italian social cooperatives in promoting the work integration process of disadvantaged workers, especially those suffering from mental disorders, from a theoretical and an empirical point of view. Social enterprise is the most popular and consolidated legal and organizational model for social enterprises in Italy, introduced by Law 381/91. Developed during the early 1980s, and formally recognized by law in the early 1990s, social cooperatives aim at pursuing the general interest of the community to promote the human needs and social inclusion of citizens. They are orientated towards aims that go beyond the interest of the business owners, the primary beneficiary of their activities is the community, or groups of disadvantaged people. In Italy, Law 381/91 distinguishes between two categories of social cooperatives, those producing goods of social utility, such as culture, welfare and educational services (A-type), and those providing economic activities for the integration of disadvantaged people into employment (B-type). The main purpose of B-type social cooperatives is to integrate disadvantaged people into the open labour market. This goal is reached after a period of training and working experience inside the firm, during which the staff works to improve both the social and professional abilities of disadvantaged people. During the years, B-type social co-ops acquired a particular relevance in the care of people with mental disorders by offering them with job opportunities. Having a job is central in the recovery process of people suffering from mental diseases, meaning that B-type social co-ops in Italy play an important rehabilitative and integrative role for this vulnerable population of workers. The

Recurrent proximal 18p monosomy and 18q trisomy in a family due to a pericentric inversion.

PubMed

Zamani, Ayse Gul; Acar, Aynur; Durakbasi-Dursun, Gul; Yildirim, M Selman; Ceylaner, Serdar; Tuncez, Ebru

2014-05-01

Here, we report on a family with pericentric inversion of chromosome 18 [inv(18)(p11.2q21)] and two recombinants with a duplication of q21 → qter and a deletion of p11.2 → pter regions in a four-generation family. This chromosomal abnormality was inherited in our first patient from the father, while it was transmitted to the second patient from the mother. Array-CGH analysis were used to better characterize duplicated and deleted chromosomal regions and showed no genomic copy number variation (CNV) differences between these two relatives. We discussed genotype-phenotype correlations including previously reported. © 2014 Wiley Periodicals, Inc.

Human papillomavirus genotypes and phylogenetic analysis of HPV-16 variants in HIV-1 infected subjects in Italy.

PubMed

Tanzi, Elisabetta; Amendola, Antonella; Bianchi, Silvia; Fasolo, M Michela; Beretta, Rosangela; Pariani, Elena; Zappa, Alessandra; Frati, Elena; Orlando, Giovanna

2009-05-29

A cross-sectional study was carried out to improve the state of evidence regarding the spectrum of HPV types and HPV-16 LCR variants circulating among men and women infected with HIV-1 in Italy. This study, conducted in 518 HIV-positive subjects (346 males and 172 females), showed a high prevalence of HPV anal infections (88.7%) in men and of cervical infections (65.1%) in women. A wide spectrum of HPV genotypes has been observed, as both single and multiple infections. Low-risk HPV types 6, 11 and 61 were frequently detected. HPV-16 was the prevalent high-risk type. Fourteen different HPV-16 LCR variants were found. Ten belonged to the European lineage (78.7% were detected in Italian subjects and 21.3% in foreign-born, all homo/bisexual men), two to the Asiatic lineage and two to the African-2 lineage. This study underlines the great genotypic heterogeneity characterizing anal and cervical HPV infections and the marked polymorphism of the predominant HPV-16 in this high-risk population in Italy.

Hepatitis A and E Viruses in Wastewaters, in River Waters, and in Bivalve Molluscs in Italy.

PubMed

Iaconelli, M; Purpari, G; Della Libera, S; Petricca, S; Guercio, A; Ciccaglione, A R; Bruni, R; Taffon, S; Equestre, M; Fratini, M; Muscillo, M; La Rosa, Giuseppina

2015-12-01

Several studies have reported the detection of hepatitis A (HAV) and E (HEV) virus in sewage waters, indicating a possibility of contamination of aquatic environments. The objective of the present study was to assess the occurrence of HAV and HEV in different water environments, following the route of contamination from raw sewage through treated effluent to the surface waters receiving wastewater discharges . Bivalve molluscan shellfish samples were also analyzed, as sentinel of marine pollution. Samples were tested by RT-PCR nested type in the VP1/2A junction for HAV, and in the ORF1 and ORF2 regions for HEV. Hepatitis A RNA was detected in 12 water samples: 7/21 (33.3%) raw sewage samples, 3/21 (14.3%) treated sewage samples, and 2/27 (7.4%) river water samples. Five sequences were classified as genotype IA, while the remaining 7 sequences belonged to genotype IB. In bivalves, HAV was detected in 13/56 samples (23.2%), 12 genotype IB and one genotype IA. Whether the presence of HAV in the matrices tested indicates the potential for waterborne and foodborne transmission is unknown, since infectivity of the virus was not demonstrated. HEV was detected in one raw sewage sample and in one river sample, both belonging to genotype 3. Sequences were similar to sequences detected previously in Italy in patients with autochthonous HEV (no travel history) and in animals (swine). To our knowledge, this is the first detection of HEV in river waters in Italy, suggesting that surface water can be a potential source for exposure .

[Self-perceived health status among immigrants in Italy].

PubMed

Petrelli, Alessio; Di Napoli, Anteo; Rossi, Alessandra; Gargiulo, Lidia; Mirisola, Concetta; Costanzo, Gianfranco

2017-01-01

to evaluate self-perceived health status of immigrants in Italy. cross-sectional study based on the representative national samples of the multipurpose surveys "Health conditions and use of health services" conducted in 2005 and 2013 by the Italian National Institute of Statistics (Istat). the study was conducted on the age group of 18-64: No. 80,661 in 2005, among which 3.2% were immigrants, and No. 72,476 in 2013, among which 7.1% were immigrants. prevalence rate ratios (PRR) calculated through log-binomial regression models, stratified by survey edition and gender, by evaluating the association between the Physical Component Score (PCS), the Mental Component Score (MCS), and the overall health index and citizenship. Adjustment for the following confounding factors was performed: age, educational level, working condition, perceived economic resources, body mass index (BMI). in 2005, immigrants had a lower probability of poor-perceived physical health, both among men (PRR: 0.79; 95%CI 0.70-0.89) and women (PRR: 0.89; 95%CI 0.82- 0.97), compared to Italians. In 2013, the perceived health advantage of immigrants was reduced for both genders (PRR males: 0.87; 95%CI 0.80-0.95; PRR females: 0.94; 95%CI 0.88-0.99). In the considered period, the prevalence of people with worse mental health conditions increases, with lower PRR among immigrants, compared to Italians. Higher probability of «NOT good» overall perceived health was also observed among immigrants residing in Italy for at least 10 years (PRR men: 1.24; PRR women: 1.15) and among immigrants men from America (PRR: 1.35). from 2005 to 2013, immigrants seemed to maintain a better perception of health status than Italians. Nevertheless, study results show a decrease in self-perceived health, particularly mental health, in the considered period - apart from demographic, socioeconomic, and lifestyle factors - as well as a worse overall self-perceived health status among immigrants who stayed in Italy longer. Such

Getting Skills Right: Italy

ERIC Educational Resources Information Center

OECD Publishing, 2017

2017-01-01

This report identifies effective strategies to tackle skills imbalances in Italy. It provides an assessment of practices and policies in the following areas: the collection and use of information on skill needs to foster a better alignment of skills acquisitions with labour market needs; the design of education and training systems and their…

A socioeconomic profile of vulnerable land to desertification in Italy.

PubMed

Salvati, Luca

2014-01-01

Climate changes, soil vulnerability, loss in biodiversity, and growing human pressure are threatening Mediterranean-type ecosystems which are increasingly considered as a desertification hotspot. In this region, land vulnerability to desertification strongly depends on the interplay between natural and anthropogenic factors. The present study proposes a multivariate exploratory analysis of the relationship between the spatial distribution of land vulnerability to desertification and the socioeconomic contexts found in three geographical divisions of Italy (north, center and south) based on statistical indicators. A total of 111 indicators describing different themes (demography, human settlements, labor market and human capital, rural development, income and wealth) were used to discriminate vulnerable from non-vulnerable areas. The resulting socioeconomic profile of vulnerable areas in northern and southern Italy diverged significantly, the importance of demographic and economic indicators being higher in southern Italy than in northern Italy. On the contrary, human settlement indicators were found more important to discriminate vulnerable and non-vulnerable areas in northern Italy, suggesting a role for peri-urbanization in shaping the future vulnerable areas. An in-depth knowledge of the socioeconomic characteristics of vulnerable land may contribute to scenarios' modeling and the development of more effective policies to combat desertification. © 2013 Elsevier B.V. All rights reserved.

Morphology and evolution of sulphuric acid caves in South Italy

NASA Astrophysics Data System (ADS)

D'Angeli, Ilenia M.; De Waele, Jo; Galdenzi, Sandro; Madonia, Giuliana; Parise, Mario; Vattano, Marco

2016-04-01

speleogenesis. Geology, 32: 369-372. De Waele J., Audra P., Madonia G., Vattano M., Plan L., D'Angeli I.M., Bigot J.-Y., Nobécourt J.-C., 2016 - Sulfuric acid speleogenesis (SAS) close to the water table: examples from southern France, Austria, and Sicily. Geomorphology, 253: 452-467. Furlani S., Cucchi F., Odorico R., 2010 - A new method to study micro-topographical changes in the intertidal zone: one year of TMEM measurements on a limestone removable slab (RRS). Z. Geomorph., 54(2): 137-151. Galdenzi S., 1997 - Initial geological observations in caves bordering the Sibari plain (southern Italy). J. Cave Karst Stud., 59: 81-86. Galdenzi S., 2012 - Corrosion of limestone tablets in sulfidic ground-water: measurements and speleogenetic implications. Int. J. Spel., 41(2): 149-159. Galdenzi S., Menichetti M., 1995 - Occurrence of hypogenic caves in a karst region: examples from central Italy. Environmental Geology, 26: 39-47. Galdenzi S., Cocchioni F., Filipponi G., Selvaggio R., Scuri S., Morichetti L., Cocchioni M., 2010 - The sulfidic thermal caves of Acquasanta Terme (central Italy). J. Cave Karst Stud. 72(1): 43-58. Jones, D.S., Polerecky, L., Galdenzi, S., Dempsey, B.A., Macalady, J.L., 2015 - Fate of sulfide in the Frasassi cave system and implications for sulfuric acid speleogenesis. Chemical Geology, 410: 21-27.

OGS improvements in 2012 in running the North-eastern Italy Seismic Network: the Ferrara VBB borehole seismic station

NASA Astrophysics Data System (ADS)

Pesaresi, D.; Romanelli, M.; Barnaba, C.; Bragato, P. L.; Durì, G.

2014-07-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Centre) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the North-eastern Italy Seismic Network: it currently consists of 17 very sensitive broad band and 18 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data centre in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of North-eastern Italy. The south-western edge of the OGS seismic network (Fig. 1) stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. OGS ha already experience in running a local seismic network in high noise conditions making use of borehole installations in the case of the micro-seismicity monitoring of a local gas storage site for a private company. Following the ML = 5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on 20 May 2012 at 02:03:53 UTC, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate the seismic response at the site. We will describe improvements in running the North-eastern Italy Seismic Network, including details of

The state of art of shotcrete in Italy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pelizza, S.; Tesio, G.G.

1995-12-31

The paper reports the large experience of use of shotcrete in Italy, both in tunnels and above ground. In tunnelling, for more than 30 years, shotcrete has been used for many hundreds of kilometers of tunnel construction. Technical rules for shotcrete use in Italy do not yet exist. SIG-Italian Tunnelling Society- has formed the Working Group Use of Shotcrete. This working group, operating since 1988, has the specific task to adapt the use of shotcrete to international standards.

[Tobacco cultivationin Salento (Apulia Region, Southern Italy) from 1929 to 1993: possible health implications].

PubMed

Montinari, Maria Rosa; Minelli, Pierluca; Gianicolo, Emilio Antonio Luca

2018-01-01

The Province of Lecce (Apulia Region, Southern Italy) is one of the Italian areas where the prevalence of respiratory disease and cancer of the respitartory tract is very high. Through a descriptive analysis of the historical series of tobacco culture indicators, a historical reconstruction of the development of tobacco cultivation in Salento (the area where the Province of Lecce is located) is here presented, in order to provide an additional element of knowledge on potential risk factors for respiratory diseases and cancers. Data regarding extensions in hectares and crop productions in the province of Lecce, in Apulia, and in Italy are from the Chamber of commerce of Lecce province and from the Italian National Institute of Statistics (Istat). From 1929 to 1993, the province of Lecce provided between 75% and 94% of the tobacco cultivated in Apulia Region and 25% of the national tobacco until 1945. Since the late Sixties, a growing increase in annual average production was observed, reaching 21.5 quintals per hectare in 1991 in Salento. This large tobacco production, associated with intensive use of pesticides, could be an element to be observed in analytical studies as a determining potential for the high prevalence of respiratory diseases and pulmonary cancers in the male population of the province of Lecce.

77 FR 23508 - Brass Sheet and Strip From France, Germany, Italy, and Japan

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-19

...)] Brass Sheet and Strip From France, Germany, Italy, and Japan Determination On the basis of the record \\1... antidumping duty orders on brass sheet and strip from France, Germany, Italy, and Japan would be likely to... from France, Germany, Italy, and Japan: Investigation Nos. 731-TA-313, 314, 317, and 379 (Third Review...

Attitudes and preferences for the clinical management of patients with hypertension and hypertension with chronic obstructive pulmonary disease in Italy: main results of a survey questionnaire.

PubMed

Tocci, Giuliano; Cicero, Arrigo F; Salvetti, Massimo; Passerini, Jasmine; Musumeci, Maria Beatrice; Ferrucci, Andrea; Borghi, Claudio; Volpe, Massimo

2015-12-01

Hypertension treatment and control represent a clinical challenge, particularly in case of concomitant risk factors and comorbidities, including chronic obstructive pulmonary disease (COPD). To evaluate attitudes and preferences for the clinical management of hypertension and hypertension associated with COPD by a large community sample of physicians in Italy. A predefined 18-item survey questionnaire was anonymously administered to both specialised physicians (SPs) and general practitioners (GPs), who have been included in an educational programme, performed between January and June 2014. A total of 1181 physicians (767 males, mean age 55.8 ± 7.3 years, average age of medical activity 27.6 ± 8.3 years), among whom 64 (5.4 %) SPs and 1117 (94.6 %) GPs, provided 21,809 valid answers to the survey questionnaire. Concomitant presence of hypertension and COPD was frequently associated (21-40 %) with hypertension-related organ damage and comorbidities. Concomitant presence of hypertension and COPD was able to affect physicians' ability to achieve the recommended therapeutic targets. To achieve the recommended BP goals, ACE inhibitors or ARBs were considered the most effective antihypertensive strategies, both in monotherapies and in combination therapies with either diuretics or calcium-channel blockers. This observational, cross-sectional survey provides useful information on physicians' attitudes and preferences for the clinical management of patients with hypertension and hypertension associated with COPD.

Bay of Naples, Italy

NASA Technical Reports Server (NTRS)

1981-01-01

The modern city of Naples (41.0N, 14.5E) and the ancient volcano of Mount Vesuvius on the shores of the Bay of Naples, Italy are the most striking features in this scene. The Roman city of Pompei, buried in the AD 79 volcano eruption can be seen on the coast just to the south of Vesuvius.

An autochthonous sexually transmitted Zika virus infection in Italy 2016.

PubMed

Grossi, Paolo Antonio; Percivalle, Elena; Campanini, Giulia; Sarasini, Antonella; Premoli, Marta; Zavattoni, Maurizio; Girello, Alessia; Dalla Gasperina, Daniela; Balsamo, Maria Luisa; Baldanti, Fausto; Rovida, Francesca

2018-01-01

We describe two cases of Zika virus infection involving an Italian patient returning from the Dominican Republic and his wife, who remained in Italy and had not travelled to Zika virus endemic areas in the previous months. The infection was transmitted through unprotected sexual intercourse after the man's return to Italy.

Use of molecular approaches in hydrogeological studies: the case of carbonate aquifers in southern Italy

NASA Astrophysics Data System (ADS)

Bucci, Antonio; Petrella, Emma; Celico, Fulvio; Naclerio, Gino

2017-06-01

Waterborne pathogens represent a significant health risk in both developed and developing countries with sensitive sub-populations including children, the elderly, neonates, and immune-compromised people, who are particularly susceptible to enteric infections. Annually, approximately 1.8 billion people utilize a faecally contaminated water source, and waterborne diseases are resulting in up to 2.1 million human mortalities globally. Although groundwater has traditionally been considered less susceptible to contamination by enteric pathogens than surface water due to natural attenuation by overlying strata, the degree of microbial removal attributable to soils and aquifers can vary significantly depending on several factors. Thus, accurate assessment of the variable presence and concentration of microbial contaminants, and the relative importance of potentially causative factors affecting contaminant ingress, is critical in order to develop effective source (well) and resource (aquifer) protection strategies. "Traditional" and molecular microbiological study designs, when coupled with hydrogeological, hydrochemical, isotopic, and geophysical methods, have proven useful for analysis of numerous aspects of subsurface microbial dynamics. Accordingly, this overview paper presents the principal microbial techniques currently being employed (1) to predict and identify sources of faecal contamination in groundwater, (2) to elucidate the dynamics of contaminant migration, and (3) to refine knowledge about the hydrogeological characteristics and behaviours of aquifer systems affected by microbial contamination with an emphasis on carbonate aquifers, which represent an important global water supply. Previous investigations carried out in carbonate aquifers in southern Italy are discussed.

TUBERCULOSIS COMO ENFERMEDAD OCUPACIONAL

PubMed Central

Mendoza-Ticona, Alberto

2014-01-01

Existe evidencia suficiente para declarar a la tuberculosis como enfermedad ocupacional en diversos profesionales especialmente entre los trabajadores de salud. En el Perú están normados y reglamentados los derechos laborales inherentes a la tuberculosis como enfermedad ocupacional, como la cobertura por discapacidad temporal o permanente. Sin embargo, estos derechos aún no han sido suficientemente socializados. En este trabajo se presenta información sobre el riesgo de adquirir tuberculosis en el lugar de trabajo, se revisan las evidencias para declarar a la tuberculosis como enfermedad ocupacional en trabajadores de salud y se presenta la legislación peruana vigente al respecto. PMID:22858771

Cell-Free DNA Analysis of Targeted Genomic Regions in Maternal Plasma for Non-Invasive Prenatal Testing of Trisomy 21, Trisomy 18, Trisomy 13, and Fetal Sex.

PubMed

Koumbaris, George; Kypri, Elena; Tsangaras, Kyriakos; Achilleos, Achilleas; Mina, Petros; Neofytou, Maria; Velissariou, Voula; Christopoulou, Georgia; Kallikas, Ioannis; González-Liñán, Alicia; Benusiene, Egle; Latos-Bielenska, Anna; Marek, Pietryga; Santana, Alfredo; Nagy, Nikoletta; Széll, Márta; Laudanski, Piotr; Papageorgiou, Elisavet A; Ioannides, Marios; Patsalis, Philippos C

2016-06-01

There is great need for the development of highly accurate cost effective technologies that could facilitate the widespread adoption of noninvasive prenatal testing (NIPT). We developed an assay based on the targeted analysis of cell-free DNA for the detection of fetal aneuploidies of chromosomes 21, 18, and 13. This method enabled the capture and analysis of selected genomic regions of interest. An advanced fetal fraction estimation and aneuploidy determination algorithm was also developed. This assay allowed for accurate counting and assessment of chromosomal regions of interest. The analytical performance of the assay was evaluated in a blind study of 631 samples derived from pregnancies of at least 10 weeks of gestation that had also undergone invasive testing. Our blind study exhibited 100% diagnostic sensitivity and specificity and correctly classified 52/52 (95% CI, 93.2%-100%) cases of trisomy 21, 16/16 (95% CI, 79.4%-100%) cases of trisomy 18, 5/5 (95% CI, 47.8%-100%) cases of trisomy 13, and 538/538 (95% CI, 99.3%-100%) normal cases. The test also correctly identified fetal sex in all cases (95% CI, 99.4%-100%). One sample failed prespecified assay quality control criteria, and 19 samples were nonreportable because of low fetal fraction. The extent to which free fetal DNA testing can be applied as a universal screening tool for trisomy 21, 18, and 13 depends mainly on assay accuracy and cost. Cell-free DNA analysis of targeted genomic regions in maternal plasma enables accurate and cost-effective noninvasive fetal aneuploidy detection, which is critical for widespread adoption of NIPT. © 2016 American Association for Clinical Chemistry.

Digital Mapping Techniques '08—Workshop Proceedings, Moscow, Idaho, May 18–21, 2008

USGS Publications Warehouse

Soller, David R.

2009-01-01

The Digital Mapping Techniques '08 (DMT'08) workshop was attended by more than 100 technical experts from 40 agencies, universities, and private companies, including representatives from 24 State geological surveys. This year's meeting, the twelfth in the annual series, was hosted by the Idaho Geological Survey, from May 18-21, 2008, on the University of Idaho campus in Moscow, Idaho. Each DMT workshop has been coordinated by the U.S. Geological Survey's National Geologic Map Database Project and the Association of American State Geologists (AASG). As in previous years' meetings, the objective was to foster informal discussion and exchange of technical information, principally in order to develop more efficient methods for digital mapping, cartography, GIS analysis, and information management. At this meeting, oral and poster presentations and special discussion sessions emphasized (1) methods for creating and publishing map products (here, "publishing" includes Web-based release); (2) field data capture software and techniques, including the use of LiDAR; (3) digital cartographic techniques; (4) migration of digital maps into ArcGIS Geodatabase format; (5) analytical GIS techniques; and (6) continued development of the National Geologic Map Database.

Hepatitis E virus and hepatitis A virus exposures in an apparently healthy high-risk population in Italy.

PubMed

Rapicetta, M; Monarca, R; Kondili, L A; Chionne, P; Madonna, E; Madeddu, G; Soddu, A; Candido, A; Carbonara, S; Mura, M S; Starnini, G; Babudieri, S

2013-02-01

The prevalence of anti-hepatitis E virus (HEV) and anti-hepatitis A virus (HAV), as well as the possible links with socio-demographic and other viral risks factors, were evaluated in an inmates population. The study population consisted of 973 consecutively recruited inmates of eight Italian prisons. The anti-HEV prevalence was 11.6 % (113/973). It increased significantly by age (χ(2) for linear trend: p = 0.001) and was significantly higher among non-Italian compared to Italian inmates (15.3 vs. 10.7 %, respectively). Age >40 years [odds ratio (OR) 2.1; 95 % confidence interval (CI) 1.4-3.1], non-Italian citizenship (OR 1.8; 95 % CI 1.1-2.9) and anti-HIV seropositivity (OR 2.2; 95 % CI 1.2-4.2) were the only factors independently associated to anti-HEV positivity by logistic regression analysis. The overall anti-HAV prevalence was 86.4 %, and was significantly higher in non-Italian compared to Italian prisoners (92.6 vs. 84.9 %, respectively; p = 0.02). Age older than 40 years (OR 3.6; 95 % CI 2.2-5.9), <5 years formal education (OR 2.1; 95 % CI 1.3-3.2) and non-Italian nationality (OR 2.7; 95 % CI 1.5-4.8) were factors independently associated to anti-HAV positivity by the logistic regression analysis. Compared to the general population, significantly higher anti-HEV and anti-HAV prevalences were observed in an inmates population in Italy. Old age and non-Italian nationality were factors independently related to both HEV and HAV exposures. This data suggest the important role of low socio-economic factors in the transmission of both infections in high-risk populations. The possible epidemiological and/or pathogenetic links between HEV and HIV exposures need to be studied further.

Synthesis of 18-hydroxy-19-norcorticosterone and 18-deoxy-19-noraldosterone. Structure determination of related 19-nor steroids by means of 2-D 1H nmr.

PubMed

Harnik, M; Kashman, Y; Carmely, S; Cojocaru, M; Dale, S L; Holbrook, M M; Melby, J C

1986-01-01

The compounds named in the title have been synthesized from the di-(ethylene ketal) of 21-hydroxy-3,20-dioxo-19-norpregn-5-ene-18, 11 beta-lactone and its 5(10)-ene isomer. Reduction of this mixture 1 with sodium aluminum bis-(methoxyethoxy)hydride furnished the 11 beta, 18, 21-triol 2a. Conversion to the 18,21-diacetate 2b, followed by deketalization to the free dione 3 and hydrolysis, afforded 18-hydroxy-19-norcorticosterone 4a which, in the solid state and probably in solution, has the 18,20-hemiacetal structure. Periodate oxidation of 4a gave 11 beta-hydroxy-3-oxo-19-norandrost-4-ene-17 beta, 18-carbolactone 5a, and acid treatment of 4a or its precursor 2a yielded 18-deoxy-19-noraldosterone 6a. The structure of 5a was confirmed by mass spectrometry and 1H nmr, and compared with that of its C-19 methyl homolog 5b and 19-noraldosterone-gamma-etiolactone 8. In particular, 2-D nmr COSY 45 experiments, affording full 1H line assignments, have rigorously established the "natural" beta (axial) configuration of the C-10 hydrogen in the 19-nor lactones 5a and 8, and therefore also in the related 4a, 6a and 19-noraldosterone 7.

Renaissance Neurosurgery: Italy's Iconic Contributions.

PubMed

Nanda, Anil; Khan, Imad Saeed; Apuzzo, Michael L

2016-03-01

Various changes in the sociopolitical milieu of Italy led to the increasing tolerance of the study of cadavers in the late Middle Ages. The efforts of Mondino de Liuzzi (1276-1326) and Guido da Vigevano (1280-1349) led to an explosion of cadaver-centric studies in centers such as Bologna, Florence, and Padua during the Renaissance period. Legendary scientists from this era, including Leonardo Da Vinci, Andreas Vesalius, Bartolomeo Eustachio, and Costanzo Varolio, furthered the study of neuroanatomy. The various texts produced during this period not only helped increase the understanding of neuroanatomy and neurophysiology but also led to the formalization of medical education. With increased understanding came new techniques to address various neurosurgical problems from skull fractures to severed peripheral nerves. The present study aims to review the major developments in Italy during the vibrant Renaissance period that led to major progress in the field of neurosurgery. Published by Elsevier Inc.

75 FR 32503 - Stainless Steel Wire Rod From Italy, Japan, Korea, Spain, and Taiwan

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

...)] Stainless Steel Wire Rod From Italy, Japan, Korea, Spain, and Taiwan Determinations On the basis of the... revocation of the antidumping duty orders on stainless steel wire rod from Italy, Japan, Korea, Spain, and... USITC Publication 4154 (May 2010), entitled Stainless Steel Wire Rod from Italy, Japan, Korea, Spain...

Combat Identification Systems COMO Integrated Air Defense Model Evaluation (CISE) Study

DTIC Science & Technology

1989-02-01

use K or IR , whichever one applies) E-6 CAA-SR-89- 3 Subroutine PDECLR 1/21/88 Before label 1000 Insert: IF (IR.GT.10) IR a 10 These changes were made...Internal Distribution: Unclassified Library 2 F-2 CAA-SR-89- 3 GLOSSARY 1. ABBREVIATIONS, ACRONYMS, AND SHORT TERMS ADM2 Air Defense Models Modification...STUDY REPORT ’ , CAA-Sn-89- 3 i , .- CD o COMBAT IDENTIFICATION SYSTEMS N COMO INTEGRATED AIR DEFENSE MODEL EVALUATION (CISE) STUDY FEBRUARY 1989

NASA Dryden research pilot Gordon Fullerton flies his final mission in NASA F/A-18B #852 in formation with NASA F/A-18A #850 on Dec. 21, 2007.

NASA Image and Video Library

2007-12-21

Long-time NASA Dryden research pilot and former astronaut C. Gordon Fullerton capped an almost 50-year flying career, including more than 38 years with NASA, with a final flight in a NASA F/A-18 on Dec. 21, 2007. Fullerton and Dryden research pilot Jim Smolka flew a 90-minute pilot proficiency formation aerobatics flight with another Dryden F/A-18 and a Dryden T-38 before concluding with two low-level formation flyovers of Dryden before landing. Fullerton was honored with a water-cannon spray arch provided by two fire trucks from the Edwards Air Force Base fire department as he taxied the F/A-18 up to the Dryden ramp, and was then greeted by his wife Marie and several hundred Dryden staff after his final flight. Fullerton began his flying career with the U.S. Air Force in 1958 after earning bachelor's and master's degrees in mechanical engineering from the California Institute of Technology. Initially trained as a fighter pilot, he later transitioned to multi-engine bombers and became a bomber operations test pilot after attending the Air Force Aerospace Research Pilot School at Edwards Air Force Base, Calif. He then was assigned to the flight crew for the planned Air Force Manned Orbital Laboratory in 1966. Upon cancellation of that program, the Air Force assigned Fullerton to NASA's astronaut corps in 1969. He served on the support crews for the Apollo 14, 15, 16 and 17 lunar missions, and was later assigned to one of the two flight crews that piloted the space shuttle prototype Enterprise during the Approach and Landing Test program at Dryden. He then logged some 382 hours in space when he flew on two early space shuttle missions, STS-3 on Columbia in 1982 and STS-51F on Challenger in 1985. He joined the flight crew branch at NASA Dryden after leaving the astronaut corps in 1986. During his 21 years at Dryden, Fullerton was project pilot on a number of high-profile research efforts, including the Propulsion Controlled Aircraft, the high-speed landing tests of sp

Non-classic 21-hydroxylase deficiency in an 18-year-old female athlete. A case report

PubMed

Silverman; Coupey; Muram

2000-05-01

Background: In non-classic 21-hydroxylase deficiency, age at presentation and genital findings are variable. Late diagnosis with dramatic signs of virilization precludes early treatment and thus prevention of anatomic and psychosocial consequences. The following case illustrates the complexity of late diagnosis.Case: An 18-year-old West Indian female was seen for evaluation of clitoromegaly and hirsutism discovered in the emergency department when she presented after sexual assault. She had allegedly been drugged and raped in her dorm room. She was a college student with an athletic scholarship and had a striking masculinized, broad-shouldered appearance. She denied any use of anabolic steroids or other drugs. Menarche was at age 16 with infrequent menses. She was sexually active with 4 life-time partners, all male. On physical exam, her height was 152 cm, weight 50 kg, blood pressure 110/70 mm Hg. Breasts were hypoplastic with hyperpigmented nipples. She was hirsute with a Ferriman-Gallwey score of 14. Genitalia were abnormal with clitoris measuring 5.5 x 1.5 cm and posterior labial fusion. Initial non-fasting serum 17-hydroxyprogesterone level was 2890 ng/dL, testosterone was 274 ng/dL, and cortisol was 9 &mgr;g/dL. Chromosome analysis was 46, XX and ACTH stimulation test confirmed the diagnosis of 21-hydroxylase deficiency. The patient was initially reluctant to begin glucocorticoid treatment because of concern that it would decrease her muscle mass and negatively impact on her athletic performance and scholarship support. One year after diagnosis and 10 months after beginning treatment, she elected surgical correction of her clitoromegaly because of extreme embarrassment over having erections during sex. She underwent excision of most of the corpus cavernosum with repositioning of the glans. The neurovascular elements were preserved. The patient is pleased with the cosmetic result and reports no change in achieving orgasm. She has not notices any change in

Microbiological survey of raw and ready-to-eat leafy green vegetables marketed in Italy.

PubMed

Losio, M N; Pavoni, E; Bilei, S; Bertasi, B; Bove, D; Capuano, F; Farneti, S; Blasi, G; Comin, D; Cardamone, C; Decastelli, L; Delibato, E; De Santis, P; Di Pasquale, S; Gattuso, A; Goffredo, E; Fadda, A; Pisanu, M; De Medici, D

2015-10-01

The presence of foodborne pathogens (Salmonella spp., Listeria monocytogenes, Escherichia coli O157:H7, thermotolerant Campylobacter, Yersinia enterocolitica and norovirus) in fresh leafy (FL) and ready-to-eat (RTE) vegetable products, sampled at random on the Italian market, was investigated to evaluate the level of risk to consumers. Nine regional laboratories, representing 18 of the 20 regions of Italy and in which 97.7% of the country's population resides, were involved in this study. All laboratories used the same sampling procedures and analytical methods. The vegetable samples were screened using validated real-time PCR (RT-PCR) methods and standardized reference ISO culturing methods. The results show that 3.7% of 1372 fresh leafy vegetable products and 1.8% of 1160 "fresh-cut" or "ready-to-eat" (RTE) vegetable retailed in supermarkets or farm markets, were contaminated with one or more foodborne pathogens harmful to human health. Copyright © 2015 Elsevier B.V. All rights reserved.

Economic Burden of Human Papillomavirus-Related Diseases in Italy

PubMed Central

Baio, Gianluca; Capone, Alessandro; Marcellusi, Andrea; Mennini, Francesco Saverio; Favato, Giampiero

2012-01-01

Introduction Human papilloma virus (HPV) genotypes 6, 11, 16, and 18 impose a substantial burden of direct costs on the Italian National Health Service that has never been quantified fully. The main objective of the present study was to address this gap: (1) by estimating the total direct medical costs associated with nine major HPV-related diseases, namely invasive cervical cancer, cervical dysplasia, cancer of the vulva, vagina, anus, penis, and head and neck, anogenital warts, and recurrent respiratory papillomatosis, and (2) by providing an aggregate measure of the total economic burden attributable to HPV 6, 11, 16, and 18 infection. Methods For each of the nine conditions, we used available Italian secondary data to estimate the lifetime cost per case, the number of incident cases of each disease, the total economic burden, and the relative prevalence of HPV types 6, 11, 16, and 18, in order to estimate the aggregate fraction of the total economic burden attributable to HPV infection. Results The total direct costs (expressed in 2011 Euro) associated with the annual incident cases of the nine HPV-related conditions included in the analysis were estimated to be €528.6 million, with a plausible range of €480.1–686.2 million. The fraction attributable to HPV 6, 11, 16, and 18 was €291.0 (range €274.5–315.7 million), accounting for approximately 55% of the total annual burden of HPV-related disease in Italy. Conclusions The results provided a plausible estimate of the significant economic burden imposed by the most prevalent HPV-related diseases on the Italian welfare system. The fraction of the total direct lifetime costs attributable to HPV 6, 11, 16, and 18 infections, and the economic burden of noncervical HPV-related diseases carried by men, were found to be cost drivers relevant to the making of informed decisions about future investments in programmes of HPV prevention. PMID:23185412

Juvenile firesetting in Italy: relationship to aggression, psychopathology, personality, self-efficacy, and school functioning.

PubMed

Del Bove, Giannetta; Caprara, Gian Vittorio; Pastorelli, Concetta; Paciello, Marinella

2008-06-01

Despite the fact that juvenile fire involvement is associated with significant injuries and is highly correlated with diverse maladjustment characteristics, firesetting has never been empirically evaluated in Italy. Participants included 567 youth between 11 and 18 years of age. This investigation attempted to address four gaps in the literature. The first objective was to examine how common firesetting behavior is among Italian youth. The second goal was to explore whether in Italy firesetting is associated with other types of psychopathology and later maladjustment. Thirdly, this study sought to extend our knowledge of the personal characteristics of firesetters. Finally, the relationship between firesetting and aggression remains an empirical question. Results suggested that almost one in three Italian youth reported engaging in fire involvement. Moreover, firesetting in Italian youth is associated with significant levels of antisocial behavior and psychopathology. In fact, firesetters-only demonstrated higher levels of most measures of maladjustment than did aggressive-only youth. Finally, the findings of this study suggest that aggressive firesetters are not at higher risk than nonaggressive firesetters. Instead, fire involvement appears to be the most important variable when predicting serious behavioral difficulties and anti-sociality. This highlights the importance of fire involvement in both the assessment and prediction of antisocial behavior and psychosocial adjustment in adolescence.

First detection of anti-Besnoitia spp. specific antibodies in horses and donkeys in Italy.

PubMed

Villa, Luca; Gazzonis, Alessia Libera; Álvarez-García, Gema; Diezma-Díaz, Carlos; Zanzani, Sergio Aurelio; Manfredi, Maria Teresa

2018-06-20

Among Apicomplexa protozoa infecting equids, Besnoitia spp., Toxoplasma gondii and Neospora spp. represent important issues from a sanitary and zootechnical viewpoint. However, only scarce epidemiological data are available on the spread of the infections in horses and donkeys in Europe. Therefore, a serosurvey was planned to estimate the prevalence of these Sarcocystidae species in Italian equids. Serum samples from 268 horses and 18 donkeys raised in Italy were collected and serologically analyzed to detect anti-Besnoitia spp., anti-T. gondii and anti-Neospora spp. antibodies: an approach based on an initial screening by in-house ELISA followed by a confirmatory WB was used. Two horses (0.7%) and four donkeys (22.2%), showed antibodies anti-Besnoitia spp. Ten horses (3.7%) resulted positive to T. gondii and one of these (0.4%) was seropositive also to Neospora spp. This is the first detection of anti-Besnoitia spp. specific antibodies in Italian horses and donkeys. The study confirmed the circulation of Besnoitia spp. among equids in Europe. Low prevalence of T. gondii and Neospora spp. in horses raised in Italy was reported. Nevertheless, it is noteworthy to consider that consumption of horse meat could represent a source for human toxoplasmosis. Copyright © 2018. Published by Elsevier B.V.

Population exposed to landslide risk in Italy

NASA Astrophysics Data System (ADS)

Trigila, Alessandro; Iadanza, Carla; Munafò, Michele; Baiocco, Fabio; Marinosci, Ines; Chiocchini, Raffaella; Mugnoli, Stefano

2013-04-01

Italy is one of the European countries most affected by landslides counting over 486,000 mass movements with a total area of 20,700 square kilometres equal to 6.9% of the national territory. Moreover Italy is a densely urbanized country: 8101 municipalities, about 200 inhabitants per sq. km, 16,000 km of rail network and 180,000 km of road network. Landslides caused more than 5000 fatalities in the last century and considerable damage to urban areas, transport infrastructure and facilities, environmental and cultural heritage. The aim of this work is to estimate the population exposed to landslide risk in Italy. The input data are: the Italian Landslide Inventory, the Italian Population Census data and the high-resolution Artificial surfaces-Imperviousness Layer (Geoland2). The Italian Landslide Inventory (Progetto IFFI) realised by ISPRA (Italian National Institute for Environmental Protection and Research) and the Regions and Self-governing Provinces, identifies landslides occurred in the national territory in accordance with standardized methods and using a detailed landslide mapping (1:10,000 scale). The 14th Population Census, made by ISTAT (Italian National Institute of Statistics) in 2001, contains data of resident population for the 382,534 census tracts in which Italy is divided. The pan-European high-resolution (HR) Artificial surfaces-Imperviousness Layer, realized using remote sensing data within the GMES initiative (Global Monitoring for Environment and Security) by European Commission and European Space Agency, contains the degree of imperviousness (between 0 and 100%). GIS overlay of this information layer (20 x 20 m grid) with census tracts has allowed the spatialization of population within urban settlements of each census tract. This methodology has been particularly useful in the case of rural census tracts characterized by large surface area and low population density. The methodology could be also applied to estimate the population exposed to

Geo-climatic heterogeneity in self-reported asthma, allergic rhinitis and chronic bronchitis in Italy.

PubMed

Pesce, G; Bugiani, M; Marcon, A; Marchetti, P; Carosso, A; Accordini, S; Antonicelli, L; Cogliani, E; Pirina, P; Pocetta, G; Spinelli, F; Villani, S; de Marco, R

2016-02-15

Several studies highlighted a great variability, both between and within countries, in the prevalence of asthma and chronic airways diseases. To evaluate if geo-climatic variations can explain the heterogeneity in the prevalence of asthma and respiratory diseases in Italy. Between 2006 and 2010, a postal screening questionnaire on respiratory health was administered to 18,357 randomly selected subjects, aged 20-44, living in 7 centers in northern, central, and southern Italy. A random-effects meta-analysis was fitted to evaluate the between-centers heterogeneity in the prevalence of asthma, asthma-like symptoms, allergic rhinitis, and chronic bronchitis (CB). A principal component analysis (PCA) was performed to synthetize the geo-climatic information (annual mean temperature, range of temperature, annual rainfalls, global solar radiations, altitude, distance from the sea) of all the 110 Italian province capital towns. The associations between these geo-climatic components obtained with PCA and the prevalence of respiratory diseases were analyzed through meta-regression models. 10,464 (57%) subjects responded to the questionnaire. There was a significant between-centers heterogeneity in the prevalence of asthma (I(2)=59.5%, p=0.022) and CB (I(2)=60.5%, p=0.019), but not in that of asthma-like symptoms or allergic rhinitis. Two independent geo-climatic components explaining together about 80% of the overall geo-climatic variability were identified: the first principally summarized the climatic variables; the second the topographic ones. Variations in the prevalence of asthma across centers were significantly associated with differences in the climatic component (p=0.017), but not with differences in the topographic one. Our findings suggest that climate play a role in determining the between-center heterogeneity in the prevalence of asthma in Italy, with higher prevalence in dry-hot Mediterranean climates, and lower in rainy-cold northern climates. Copyright © 2015

Exploring the variability in antibiotic prescribing profiles among paediatricians from two different areas of Italy.

PubMed

Cucinotta, Giovanni; Mazzaglia, Giampiero; Toscano, Maria A; Arcoraci, Vincenzo; Tempera, Gianna; Salmeri, Mario; Rosignoli, Mario; Bottaro, Gaetano; Boccazzi, Antonio; Nicoletti, Giuseppe; Caputi, Achille P

2002-05-01

We carried out a multicentre community-based study in order to describe the antibiotic therapeutic approach of paediatricians from two different areas of Italy in the treatment of respiratory tract infection (RTIs), and to assess which factors are involved in a possible variability of prescribing habits. Forty paediatricians participated in the study between October 1998 and April 1999. They had to complete a questionnaire for each therapeutic intervention resulting in an antibiotic prescription. A logistic regression model was used to identify possible predictors in choosing parenteral antibiotics for the treatment of RTIs. In 2 975 questionnaires of antibiotic treatment, RTIs represented 90.2% of the total antibiotics used. Upper respiratory tract infections were the most commonly treated diagnostic group (59.6%), followed by lower respiratory tract infections (20.4%), and middle ear infections (19.8%). Statistically significant differences between northern and southern Italy were reported in the antibiotic prescription profile and the duration of the therapy. Another marked difference was reported in the frequency of laboratory analysis requests. The logistic regression model indicated that the use of parenteral antibiotics appears significantly related to the type of infections [lower RTIs: (OR: 3.99; 95% CI: 2.49-6.37)], the geographic location [northern Italy: (OR: 0.20; 95% CI: 0.20-0.39)], and the presence of concurrent diseases (OR: 3.21; 95% CI: 1.46-7.02). The lack of adherence to clinical guidelines and the marked variability of antibiotic prescription rates between different areas of the country appear to be related to factors other than bacterial resistance, and highlight the importance of carrying out educational programmes targeted at the national level for improving the antibiotic prescription habits for the treatment of RTIs.

The social cost of rheumatoid arthritis in Italy: the results of an estimation exercise.

PubMed

Turchetti, G; Bellelli, S; Mosca, M

2014-03-14

The objective of this study is to estimate the mean annual social cost per adult person and the total social cost of rheumatoid arthritis (RA) in Italy. A literature review was performed by searching primary economic studies on adults in order to collect cost data of RA in Italy in the last decade. The review results were merged with data of institutional sources for estimating - following the methodological steps of the cost of illness analysis - the social cost of RA in Italy. The mean annual social cost of RA was € 13,595 per adult patient in Italy. Affecting 259,795 persons, RA determines a social cost of € 3.5 billions in Italy. Non-medical direct cost and indirect cost represent the main cost items (48% and 31%) of the total social cost of RA in Italy. Based on these results, it appears evident that the assessment of the economic burden of RA solely based on direct medical costs evaluation gives a limited view of the phenomenon.

Report on religious slaughter practices in Italy.

PubMed

Novelli, Sara

2016-01-01

The term 'religious slaughter' commonly refers to the practice of killing animals without stunning, according to the precepts of Jewish and Muslim religions. The aim of this paper is to assess the situation concerning ritual slaughtering in not-stun bovines, small ruminants, and poultry in Italy in 2012. The study was divided into 2 phases. During the rst phase, preliminary data about all slaughterhouses authorized for ritual slaughter in Italy in 2012 are collected through the compilation of a questionnaire sent to each plants. The second step involved a sampling of not-stun animals religiously slaughtered in 5 selected plants. Authors collected and compiled all informations about management, restrain system and rite taking into account in particular animal welfare.

75 FR 78223 - Certain Pasta From Italy: Preliminary Results of Countervailing Duty Changed Circumstances Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-15

... DEPARTMENT OF COMMERCE International Trade Administration [C-475-819] Certain Pasta From Italy... certain pasta from Italy. See Certain Pasta From Italy: Notice of Initiation of Changed Circumstances... Notice''). The Department confirmed that New World Pasta Company, Dakota Growers Pasta Company, and...

Biodiversity of entomopathogenic nematodes in Italy.

PubMed

Tarasco, E; Clausi, M; Rappazzo, G; Panzavolta, T; Curto, G; Sorino, R; Oreste, M; Longo, A; Leone, D; Tiberi, R; Vinciguerra, M T; Triggiani, O

2015-05-01

An investigation was carried out on the distribution and biodiversity of steinernematid and heterorhabdtid entomopathogenic nematodes (EPN) in nine regions of Italy in the period 1990-2010. More than 2000 samples were collected from 580 localities and 133 of them yielded EPN specimens. A mapping of EPN distribution in Italy showed 133 indigenous EPN strains belonging to 12 species: 43 isolates of Heterorhabditis bacteriophora, 1 of H. downesi, 1 of H. megidis, 51 of Steinernema feltiae, 12 of S. affine, 4 of S. kraussei, 8 of S. apuliae, 5 of S. ichnusae, 3 of S. carpocapsae, 1 of S. vulcanicum, 3 of Steinernema 'isolate S.sp.MY7' of 'S. intermedium group' and 1 of S. arenarium. Steinernematids are more widespread than heterorhabditids and S. feltiae and H. bacteriophora are the most commonly encountered species. Sampling sites were grouped into 11 habitats: uncultivated land, orchard, field, sea coast, pinewood, broadleaf wood, grasslands, river and lake borders, caves, salt pan and moist zones; the soil texture of each site was defined and the preferences of habitat and soil texture of each species was assessed. Except for the two dominant species, S. feltiae and H. bacteriophora, EPN occurrence tends to be correlated with a specific vegetation habitat. Steinernema kraussei, H. downesi and H. megidis were collected only in Sicily and three of the species recently described - S. apuliae, S. ichnusae and S. vulcanicum - are known only from Italy and seem to be endemic.

Epidemiology of breast-feeding in Italy.

PubMed

Giovannini, M; Banderali, G; Agostoni, C; Riva, E

2001-01-01

To evaluate the prevalence of breast-feeding in Italy and to describe the social and environmental factors associated with its practice, 1601 mothers were systematically recruited as representative of deliveries across all regions of Italy during November 1995. They were interviewed in March, June, and September of 1996. Interviews were conducted by telephone using a standardized questionnaire designed for computer scanning. The results indicated that 85% of mothers breast-fed their infants. The rates of breast-feeding at 3, 6, and 9 months were, respectively, 51%, 32%, and 19%. Among the 830 lactating mothers at 3 months, 72% practiced breast-feeding "on demand." Pediatricians, midwives, and gynecologists were the main sources of information about breast-feeding, but 43% of the mothers did not receive any information. Media (radio, TV) were mentioned as sources of information by only 2% of the mothers. Maternal factors significantly associated with breast-feeding and its duration were: a) having been breast-fed as infants, b) being nonsmokers, and c) being given information about lactation at the time of discharge from their hospital ward. Maternal characteristics (age, weight, and height), parental socioeconomic indicators (profession and education), and neonatal care (rooming-in practice) were not significantly associated with breast-feeding. Our results show that in Italy a fairly high percentage of mothers start breast-feeding and that both maternal factors (history and habits) and good information may support its duration.

Italy seeks geothermal renaissance

NASA Astrophysics Data System (ADS)

Cartlidge, Edwin

2009-03-01

Scientists in Italy are hoping to once again put their country at the forefront of geothermal energy research, by extracting power from one of the Earth's most explosive volcanic areas. Later this year they will drill a well 4 km deep into Campi Flegrei, a geological formation lying just to the west of Naples known as a caldera, which formed from the collapse of several volcanoes over thousands of years.

7 CFR 6.21 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

.... EC 12. Belgium, Denmark, the Federal Republic of Germany, France, Greece, Ireland, Italy, Luxembourg... Federal Republic of Germany, Finland, France, Greece, Ireland, Italy, Luxembourg, the Netherlands...

7 CFR 6.21 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

.... EC 12. Belgium, Denmark, the Federal Republic of Germany, France, Greece, Ireland, Italy, Luxembourg... Federal Republic of Germany, Finland, France, Greece, Ireland, Italy, Luxembourg, the Netherlands...

7 CFR 6.21 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

.... EC 12. Belgium, Denmark, the Federal Republic of Germany, France, Greece, Ireland, Italy, Luxembourg... Federal Republic of Germany, Finland, France, Greece, Ireland, Italy, Luxembourg, the Netherlands...

7 CFR 6.21 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

.... EC 12. Belgium, Denmark, the Federal Republic of Germany, France, Greece, Ireland, Italy, Luxembourg... Federal Republic of Germany, Finland, France, Greece, Ireland, Italy, Luxembourg, the Netherlands...

7 CFR 6.21 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

.... EC 12. Belgium, Denmark, the Federal Republic of Germany, France, Greece, Ireland, Italy, Luxembourg... Federal Republic of Germany, Finland, France, Greece, Ireland, Italy, Luxembourg, the Netherlands...

Prevalence and cardiovascular risk profile of chronic kidney disease in Italy: results of the 2008-12 National Health Examination Survey.

PubMed

De Nicola, Luca; Donfrancesco, Chiara; Minutolo, Roberto; Lo Noce, Cinzia; Palmieri, Luigi; De Curtis, Amalia; Iacoviello, Licia; Zoccali, Carmine; Gesualdo, Loreto; Conte, Giuseppe; Vanuzzo, Diego; Giampaoli, Simona

2015-05-01

National surveys in countries outside Europe have reported a high prevalence (11-13%) of chronic kidney disease (CKD). Studies in Europe have provided a variable prevalence likely due to differences in study design, including age and extent of geographic areas, equation used to evaluate estimated glomerular filtration rate (eGFR) and CKD stages examined. The 2008-12 National Health Examination Survey in Italy randomly extracted samples from the general population aged 35-79 years, stratified by age and gender, from the resident list of each Italian region (440 persons/1.5 million of residents). We estimated the prevalence of CKD by means of urinary albumin : creatinine ratio and eGFR (CKD-EPI equation-enzymatic assay of serum creatinine). Cardiovascular (CV) risk profile was also evaluated. Three thousand eight hundred and forty-eight men and 3704 women were examined. In the whole population, mean age was 57 ± 12 and 56 ± 12 years in men and women, respectively; hypertension was prevalent in men and women, respectively (56 and 43%) and the same held true for overweight (48 and 33%), obesity (26 and 27%), diabetes (14 and 9%) and smoking (21 and 18%), whereas CV disease was less frequent (9 and 6%). Overall, the prevalence of CKD (95% confidence interval) was 7.05% (6.48-7.65). Early stages constituted 59% of the CKD population [Stage G1-2 A2-3: 4.16% (3.71-4.61) and Stage G3-5: 2.89% (2.51-3.26)]. At multivariate regression analysis, age, obesity, hypertension, diabetes, CV disease and smoking were all independent correlates of CKD. CKD has a relatively lower prevalence in Italy, in particular for advanced stages, when compared with similar national surveys outside Europe. This occurs despite older age and unfavourable CV risk profile of the whole population. © The Author 2014. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Aging in Italy: The Need for New Welfare Strategies in an Old Country.

PubMed

Mazzola, Paolo; Rimoldi, Stefania Maria Lorenza; Rossi, Paolo; Noale, Marianna; Rea, Federico; Facchini, Carla; Maggi, Stefania; Corrao, Giovanni; Annoni, Giorgio

2016-06-01

Italy, a Southern European country with 60.8 million inhabitants, has the largest proportion of elderly citizens (aged ≥65) in Europe of 21.4%. The aging of the population is due to a number of reasons, such as baby boomers growing old, an increase in longevity, and low birth rate. Although international migration has increased in recent years, the addition of a foreign segment of the population has neither compensated for nor significantly curtailed the aging phenomenon. The impact of aging on the economic sustainability concerns the progressive reduction of the workforce, high incidence of pension spending in the overall resources allocated to welfare, recent reform of the pension system, and the growing issue of "non-self-sufficiency" in the elderly. Despite limited financial measures dedicated to research, Italy is conducting important studies on aging, both at the national and international level. Physicians and researchers in the field of geriatrics and gerontology are not only promoting quality of life in the elderly, and healthy-active aging, but also contributing to economic stability and social organization. Finally, nutritional and lifestyle habits-and their role in preventing chronic diseases-are the focus of the current international event EXPO 2015, with many sections dedicated to the elderly. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Provision of mental health care in general practice in Italy.

PubMed Central

Tansella, M; Bellantuono, C

1991-01-01

The main features of the psychiatric system and of the general practice system in Italy since the psychiatric reform and the introduction of a national health service are briefly described. Research conducted in Italy confirms that a large proportion of patients seen by general practitioners have psychological disorders and that only some of those patients whose psychological problems are identified by general practitioners are referred to specialist psychiatric care. Thus, the need to identify the best model of collaboration between psychiatric services and general practice services is becoming increasingly urgent. The chances of improving links between the two services and of developing a satisfactory liaison model are probably greater in countries such as Italy where psychiatric services are highly decentralized and community-based, than in countries where the psychiatric services are hospital-based. PMID:1807308

A foetal tile from an archaeological site: anthropological investigation of human remains recovered in a medieval cemetery in Northern Italy.

PubMed

Licata, Marta; Rossetti, Chiara; Tosi, Adelaide; Badino, Paola

2018-06-01

The recovery of foetal remains is very sporadic in archaeology, especially due the scarce degree of bone mineralisation. This paper presents the singular archaeological discovery of a foetal tile preserving the bone remains, object of our anthropological examination. The foetal tile was discovered during an archaeological excavation in a medieval site (Northern Italy). The tile was analysed by CT scan and later, human remains were anthropologically examined. The archaeological investigation revealed a special ritual destined to foetuses while forensic anthropological analysis allowed estimating the gestational age near to 21-24 weeks.

Immunisation registers in Italy: a patchwork of computerisation.

PubMed

Alfonsi, V; D'Ancona, F; Rota, M C; Giambi, C; Ranghiasci, A; Iannazzo, S

2012-04-26

In Italy, the 21 regional health authorities are in charge of organising and implementing their own vaccination strategy, based on the national vaccine plan. Immunisation coverage varies greatly among the regions for certain vaccines. Efforts to increase childhood immunisation coverage have included initiatives to develop and implement computerised immunisation registers in as many regions as possible. We undertook a cross-sectional online survey in July 2011 to provide an updated picture of the use, heterogeneity and main functions of different computerised immunisation registers used in the Italian regions and to understand the flow of information from local health units to the regional authorities and to the Ministry of Health. Comparing current data with those obtained in 2007, a substantial improvement is evident. A total of 15 regions are fully computerised (previously nine), with 83% of local health units equipped with a computerised register (previously 70%). Eight of the 15 fully computerised regions use the same software, simplifying data sharing. Only four regions are able to obtain data in real time from local health units. Despite the progress made, the capacity to monitor vaccination coverage and to exchange data appears still limited.

Italy: An Open Air Museum

NASA Astrophysics Data System (ADS)

Pizzorusso, Ann

2016-04-01

Imagine if you could see the River Styx, bathe in the Fountain of Youth, collect water which enhances fertility, wear a gem that heals bodily ailments, understand how our health is affected by geomagnetic fields, venture close to the flames of Hell on Earth and much, much, more. Know something? These things exist - on Earth - today - in Italy and you can visit them because Italy is an open air museum. Ann C. Pizzorusso, in her recent book, reveals how Italy's geology has affected its art, literature, architecture, religion, medicine and just about everything else. She explores the geologic birth of the land, describing the formation of the Alps and Apennines, romantic bays of Tuscany and Lazio, volcanoes of the south and Caribbean-like beaches of Puglia. But that's not all, from the first pages of this visually stunning book, the reader has the impression of being in an art museum, where one can wander from page to page to satisfy one's curiosity-- guided from time to time by the Etruscan priests, Virgil, Dante, Goethe or Leonardo da Vinci himself. Pizzorusso stitches together widely diverse topics - such as gemology, folk remedies, grottoes, painting, literature, physics and religion - using geology as a thread. Quoting everyone from Pliny the Elder to NASA physicist Friedemann Freund, the work is solidly backed scholarship that reads as easily as a summer novel. Wonderfully illustrated with many photos licensed from Italian museums, HRH Elizabeth II and the Ministero Beni Culturali the book highlights the best works in Italian museums and those outside in the "open air museums." This approach can be used in any other country in the world and can be used for cultural tourism (a tour following the book has been organized for cultural and university groups), an ideal way of linking museums to the surrounding landscape.

Southern Italy, Instrument Pointing Subsystem

NASA Image and Video Library

1985-08-06

51F-32-024 (29 July - 6 August 1985) --- Italy's “boot heel" surrounded by waters of the Ionian Sea/Golfo di Taranto and the Adriatic Sea is very clearly visible in this scene made with a handheld 70mm camera. Spacelab 2's versatile instrument pointing system (IPS) protrudes from the cargo bay.

Discourses of Merit. The Hot Potato of Teacher Evaluation in Italy

ERIC Educational Resources Information Center

Barzanò, Giovanna; Grimaldi, Emiliano

2013-01-01

Italy is well known for its difficulty in introducing any educational evaluation system. This paper explores the dynamics which occurred in Italy in 2010-2011, within the context of the umpteenth national pilot of school and staff evaluation. Our research object is an unfinished project, observed in its development. We get close to the struggles…

In A Queer Place in Time: Fictions of Belonging in Italy 1890-2010

NASA Astrophysics Data System (ADS)

Atwood, Christopher Burke

In a Queer Place in Time: Fictions of Belonging in Italy 1890-2010 maps the "elsewheres"---spatial, temporal and intertextual--- that authorize same-sex desire in modern Italy. Tracing a genealogy that spans from nineteenth century travel writing about Italy to contemporary Italian novels, I argue that texts exported from the Northern Europe and the U.S. function as vital site of affiliation and vexing points of discrepancy for Italy's queers. Pier Vittorio Tondelli's Camere separate (1989), for instance, cites the British novelist Christopher Isherwood as proof that -- somewhere else -- silence did not yoke homosexuality. Rather than defining sexuality as a constant set of desires, I demonstrate it to be a retroactive fiction. It is the fleeting affinity that the reading of inherited texts can evoke. In examining the reception of transnational gay narratives in the national context of Italy, this dissertation argues that the concept of "Western" homosexuality is internally riven. Ultimately, In a Queer Place in Time illuminates how local histories -- including affective differences like shame, estrangement and backwardness -- continue to haunt gay culture's global fictions. !

Estimates of the Number of People Living with HIV in Italy

PubMed Central

Regine, Vincenza; Stanecki, Karen; Salfa, Maria Cristina; Raimondo, Mariangela; Suligoi, Barbara

2014-01-01

Objective. To estimate the HIV prevalence and the number of people living with HIV (PLHIV) in Italy with a projection for 2020. Methods. Two methods elaborated by Joint United Nations Programme on HIV/AIDS (UNAIDS) were used: Estimate and Projection Package and Spectrum. Results. A total of 123,000 (115,000–145,000) individuals aged 15 or more were estimated to be living with HIV in Italy at the end of 2012 and the estimated HIV prevalence was 0.28 (0.24–0.32) per 100 residents aged 15 or more. In 2012, the estimated number of new HIV infections among adults was 3,000 (2,700–4,000), and the number of adults in need for ART was 93,000 (80,000–110,000). The projection estimates that 130,000 (110,000–150,000) adults will live with HIV/AIDS in 2020 in Italy. Conclusion. Estimates of PLHIV in Italy stress the high number of PLHIV in need of care and treatment, as well as the need for more information and prevention campaigns. PMID:25136562

Investigation of VLF and LF transmitter signals prior to earthquakes in Italy and in Greece recorded in the year 2016

NASA Astrophysics Data System (ADS)

Boudjada, Mohammed Y.; Schwingenschuh, Konrad; Eichelberger, Hans; Rozhnoi, Alexander; Besser, Bruno; Biagi, Pier F.; Magnes, Werner; Lammer, Helmut; Stachel, Manfred

2017-04-01

We analyze the VLF and LF transmitter signals recorded in the year 2016 by the Graz seismo-electromagnetic facility (15.43 E, 47.06 N), as part of the European VLF receiver network. The regular VLF/LF signals received at Graz are from: Germany (DHO, 23.4 kHz), Great Britain (GBS, 19.58 kHz), Island (NRK, 37.5 kHz), Italy (ICV, 20.27 kHz; ITS, 45.9 kHz), Turkey (TBB, 26.7 kHz) and USA (NPM, 21.4; NAA, 24.0 kHz). A first part of our contribution will emphasize on the signal reception conditions and the geomagnetic and solar effects. The amplitude and the phase of the transmitter signals are considered and separated in day- and night-time observations. A second part will be devoted to the investigation of earthquakes events which principally occurred in the Southern Europe, i.e. in Greece and in Italy. In this context the propagation paths between the transmitter and the receiver are taken into consideration. Particular attention is given to the transmitters localized in the surrounding regions where the earthquakes occurred. It is the case of three stations, two in Italy (ICV and ITS) and one in Turkey (TBB). We show that attenuations and/or absences of the VLF/LF intensity signals may be considered. Our main outcomes are discussed and combined to previous investigations in particular those which referred to the L'Aquila earthquakes of April 2009.

A boy with partial dup(18q)/del(18p) due to a maternal pericentric inversion: Genotype-phenotype correlation and risk of recombinant chromosomes based on systematic review of the literature.

PubMed

Lustosa-Mendes, Elaine; Dos Santos, Ana Paula; Viguetti-Campos, Nilma Lúcia; Vieira, Társis Paiva; Gil-da-Silva-Lopes, Vera Lúcia

2017-01-01

We report a boy carrying a recombinant chromosome 18, with terminal deletion of 10.8 Mb from 18p11.32 to 18p11.21 and a terminal duplication of 22.8 Mb from 18q21.31 to 18q23, resulting from a maternal pericentric inversion of the chromosome 18. He presented with poor growth, developmental delay, facial dysmorphisms, surgically repaired left cleft lip and palate, a mild form of holoprosencephaly characterized by single central incisor and agenesis of the septum pellucidum, and body asymmetry. Based on the systematic review of the literature, we discuss genotype-phenotype correlation and the risk for the recombinants of pericentric inversions of chromosome 18. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Agricultural, domestic and handicraft folk uses of plants in the Tyrrhenian sector of Basilicata (Italy)

PubMed Central

Salerno, Giovanni; Guarrera, Paolo Maria; Caneva, Giulia

2005-01-01

Background Research was carried out into agricultural and domestic-handicraft uses in folk traditions in the Tyrrhenian sector of the Basilicata region (southern Italy), as it is typically representative of ethnobotanical applications in the Mediterranean area. From the point of view of furnishing a botanical support for the study of local "material culture" data was collected through field interviews of 49 informants, most of whom were farmers. Results The taxa cited are 60, belonging to 32 botanical families, of which 18 are employed for agricultural uses and 51 for domestic-handicraft folk uses. Data show a diffuse use of plants for many purposes, both in agricultural (present uses 14%; past uses 1%) and for domestic-handicraft use (present uses 40%; past uses 45%); most of the latter are now in decline. Conclusion 60 data look uncommon or typical of the places studied. Some domestic-handicraft folk uses are typical of southern Italy (e.g. the use of Ampelodesmos mauritanicus for making ties, ropes, torches, baskets or that of Acer neapolitanum for several uses). Other uses (e.g. that of Inula viscosa and Calamintha nepeta for peculiar brooms, and of Origanum heracleoticum for dyeing wool red) are previously unpublished. PMID:16270919

Characterization of levofloxacin non-susceptible clinical Streptococcus pyogenes isolated in the central part of Italy.

PubMed

Petrelli, D; Di Luca, M C; Prenna, M; Bernaschi, P; Repetto, A; Vitali, L A

2014-02-01

We investigated the prevalence, genetics, and clonality of fluoroquinolone non-susceptible isolates of Streptococcus pyogenes in the central part of Italy. S. pyogenes strains (n = 197) were isolated during 2012 from patients with tonsillopharyngitis, skin, wound or invasive infections and screened for fluoroquinolone non-susceptibility (resistance to norfloxacin and levofloxacin minimum inhibitory concentration (MIC) = 2 mg/L) following EUCAST guidelines. First-step topoisomerase parC and gyrA substitutions were investigated using sequencing analysis. Clonality was determined by pulsed field gel electrophoresis (PFGE; SmaI digestion) and by emm typing. The fluoroquinolone non-susceptible phenotype was identified in 18 isolates (9.1 %) and correlated with mutations in parC, but not in gyrA, the most frequent leading to substitution of the serine at position 79 with an alanine. Most of the fluoroquinolone non-susceptible isolates belonged to the emm-type 6, even if other emm-types were also represented (emm75, emm89, and emm2). A significant level of association was measured between PFGE and both emm type and substitutions in parC. The prevalence of fluoroquinolone non-susceptible Streptococcus pyogenes isolates in Italy is of concern and, although the well-known emm type 6 is dominant, other types are appearing and spreading.

76 FR 42114 - Granular Polytetrafluoroethylene Resin From Italy: Continuation of Antidumping Duty Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-18

... (``PTFE resin'') from Italy would likely lead to a continuation or recurrence of dumping and material... initiation of the third sunset review of the antidumping duty order on PTFE resin from Italy, pursuant to...

The CARIPANDA project: Climate change and water resources in the Adamello Natural Park of Italy

NASA Astrophysics Data System (ADS)

Bocchiola, D.

2009-04-01

The three years (2007-2009) CARIPANDA project funded by the Cariplo Foundation of Italy is aimed to evaluate scenarios for water resources in the Adamello natural Park of Italy in a window of 50 years or so (until 2050). The project is led by Ente Parco Adamello and involves Politecnico di Milano, Università Statale di Milano, Università di Brescia, and ARPA Lombardia as scientific partners, while ENEL hydropower Company of Italy joins the project as stake holder. The Adamello Natural Park is a noteworthy resource in the Italian Alps. The Adamello Group is made of several glacierized areas (c. 24 km2), of both debris covered and free ice types, including the widest Italian Glacier, named Adamello, spreading on an area of about c. 18 km2. Also the Adamello Natural Reserve, covering 217 km2 inside the Adamello Park and including the Adamello glaciers, hosts a number of high altitude safeguarded vegetal and animal species, the safety of which is a primary task of the Reserve. Project's activity involves analysis of local climate trend, field campaigns on glaciers, hydrological modelling and remote sensing of snow and ice covered areas, aimed to build a consistent model of the present hydrological conditions and of the areas. Then, properly tailored climate change projections for the area, obtained using local data driven downscaling of climate change projections from GCMs model, are used to infer the likely response to expected climate change conditions. With two years in the project now some preliminary findings can be highlighted and some preliminary trend analysis carried out. The proposed poster provides a resume of the main results of the project insofar, of interest as a benchmark for similar ongoing and foregoing projects about climate change impact on European mountainous natural areas.

Agip oil discovery near Milan may fuel Italy's next expansion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-06-20

A promising crude oil discovery by Agip SpA just over 18 miles northwest of Milan could set Italy on course for another substantial expansion in oil production. Flow was boosted last year by the start-up of output from the country's biggest oil deposit, the Vega field offshore Sicily. Vega production is scheduled to reach a peak of 60,000 b/d, but the average production for 1988 is expected to be only 25,000 b/d because of water production problems. Italian crude-oil production averaged 80,137 b/d during 1987 with Agip contributing 47,260 b/d. This year output it projected to rise to more thanmore » 82,000 b/d. Development of Agip's new discovery is likely to be fraught with difficulties. The successful wildcat and the initial appraisal program was in a national park along the River Ticino, a tributary of the River Po.« less

Karst geomorphology and hydrology at the Campania - Basilicata border (southern Apennines of Italy)

NASA Astrophysics Data System (ADS)

Farfan Gonzalez, H.; Parise, M.

2009-04-01

This paper describes the main karst geomorphological and hydrological features of the area at the boundary between the Campania and Basilicata regions, in the southern Apennines of Italy. Even not far from the most important karst area of southern Italy (the Alburni Massif, hosting hundreds of caves, with very complex subterranean systems that have been extensively explored in the last 50 years), this sector has never been object of detailed karstic studies. Geologically, it shows a carbonate bedrock consisting of Cretaceous limestones and dolomites, in tectonic contact with terrigenous deposits of Miocene age. The territory is an active seismogenic zone, as testified by the November 23, 1980, earthquake that hit this part of southern Italy with a 6.8 magnitude, causing over 2,700 victims and destroying several small towns in the two regions. In 2007, within the framework of joint projects between the Italian Speleological Society (SSI) and the Cuban Speleological Society (SEC), a scientific and speleological expedition was carried out in a sector of this area. The efforts produced during the expedition, and in the preceeding phases as well, resulted in discovery, survey and documentation of 62 caves, and in supporting the progresses of the exploration activities in the main karst system in the area, a complex of two caves that reach a maximum depth of 123 meters and an overall length of 1,8 km. At the surface, a variety of karst landforms is recognizable. The main carbonate ridges show several orders of palaeosurfaces, located at different heights above sea level. Bounded by fault lines or fault line scarps, they present variable extension, the highest surfaces showing a much better continuity. On the Campanian side, several sinkholes are also present, some of which opened in the aftermath of the 1980 earthquake. The same event caused in Basilicata the formation of several caves of structural origin, controlled in their development by tectonics and extremely

Polychlorinated biphenyls (PCBs) in the atmosphere of sub-alpine northern Italy.

PubMed

Castro-Jiménez, J; Dueri, S; Eisenreich, S J; Mariani, G; Skejo, H; Umlauf, G; Zaldívar, J M

2009-03-01

The main objective of this work was to assess the atmospheric concentrations and seasonal variations of selected POPs in a sub-alpine location where few data are available. A monitoring and research station was set up at the JRC Ispra EMEP site (Italy). We present and discuss a one-year data set (2005-2006) on PCB air concentrations. Sigma 7PCBs monthly averaged concentration varied from 31 to 76 pgm(-3). Concentrations in the gas phase (21-72 pgm(-3)) were higher than those in the particulate phase (3-10 pgm(-3)). Advection of air masses and re-volatilization from local sources seem to play a dominant role as drivers of PCB atmospheric concentrations in the area. Indications of seasonal variation affecting PCB congener patterns and the gas/particulate partitioning were found. Modeling calculations suggest a predominant importance of the wet deposition in this region (1 microgm(-2)yr(-1) Sigma 7PCBs yearly total wet deposition flux; 650-2400 pgL(-1) rainwater concentrations).

Double-hit lymphoma demonstrating t(6;14;18)(p25;q32;q21), suggesting two independent dual-hit translocations, MYC/BCL-2 and IRF4/BCL-2.

PubMed

Tabata, Rie; Yasumizu, Ryoji; Tabata, Chiharu; Kojima, Masaru

2013-01-01

Here, we report a rare case of double-hit lymphoma, demonstrating t(6;14;18)(p25;q32;q21), suggesting two independent dual-translocations, c-MYC/BCL-2 and IRF4/BCL-2. The present case had a rare abnormal chromosome, t(6;14;18)(p25;q32;q21), independently, in addition to known dual-hit chromosomal abnormalities, t(14;18)(q32;q21) and t(8;22)(q24;q11.2). Lymph node was characterized by a follicular and diffuse growth pattern with variously sized neoplastic follicles. The intrafollicular area was composed of centrocytes with a few centroblasts and the interfollicular area was occupied by uniformly spread medium- to large-sized lymphocytes. CD23 immunostaining demonstrated a disrupted follicular dendritic cell meshwork. The intrafollicular tumor cells had a germinal center phenotype with the expression of surface IgM, CD10, Bcl-2, Bcl-6, and MUM1/IRF4. However, the interfollicular larger cells showed plasmacytic differentiation with diminished CD20, Bcl-2, Bcl-6, and positive intracytoplasmic IgM, and co-expression of MUM1/IRF4 and CD138 with increased Ki-67-positive cells (> 90%). MUM1/IRF4 has been found to induce c-MYC expression, and in turn, MYC transactivates MUM1/IRF4, creating a positive autoregulatory feedback loop. On the other hand, MUM1/IRF4 functions as a tumor suppressor in c-MYC-induced B-cell leukemia. The present rare case arouses interest in view of the possible "dual" activation of both c-MYC and MUM1/IRF4 through two independent dual-translocations, c-MYC/BCL-2 and IRF4/BCL-2.

OGS improvements in the year 2011 in running the Northeastern Italy Seismic Network

NASA Astrophysics Data System (ADS)

Bragato, P. L.; Pesaresi, D.; Saraò, A.; Di Bartolomeo, P.; Durı, G.

2012-04-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Center) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 15 very sensitive broad band and 21 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data center in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of Northeastern Italy. Since 2002 OGS-CRS is using the Antelope software suite on several workstations plus a SUN Cluster as the main tool for collecting, analyzing, archiving and exchanging seismic data, initially in the framework of the EU Interreg IIIA project "Trans-national seismological networks in the South-Eastern Alps". SeisComP is also used as a real time data exchange server tool. In order to improve the seismological monitoring of the Northeastern Italy area, at OGS-CRS we tuned existing programs and created ad hoc ones like: a customized web server named PickServer to manually relocate earthquakes, a script for automatic moment tensor determination, scripts for web publishing of earthquake parametric data, waveforms, state of health parameters and shaking maps, noise characterization by means of automatic spectra analysis, and last but not least scripts for email/SMS/fax alerting. The OGS-CRS Real Time Seismological website (RTS, http://rts.crs.inogs.it/) operative since several years was initially developed in the framework of the Italian DPC-INGV S3 Project: the RTS website shows classic earthquake locations

Retrospective Study of Hemoparasites in Cattle in Southern Italy by Reverse Line Blot Hybridization

PubMed Central

CECI, Luigi; IARUSSI, Fabrizio; GRECO, Beatrice; LACINIO, Rosanna; FORNELLI, Stefania; CARELLI, Grazia

2014-01-01

ABSTRACT Tick-borne diseases are widespread in tropical and temperate regions and are responsible for important economic losses in those areas. In order to assess the presence and prevalence of various pathogens in southern Italy, we retrospectively analyzed cattle blood samples collected for a previous study in 2000 using reverse line blot (RLB) hybridization. The study had been carried out in three regions of southern Italy on 1,500 randomly selected and apparently healthy adult cattle. RLB showed that 43.7% of the cattle were positive for nine different species of hemoparasites with either a single infection or a mixed infection. Theileria buffeli was the most common species found, being present in 27.3% of the animals, followed by Anaplasma marginale in 18.1%, Anaplasma centrale in 13.8%, Babesia bigemina and Anaplasma bovis in 4.2%, Anaplasma phagocytophilum in 1.7%, Babesia bovis in 1.6%, Babesia major in 0.2% and Babesia divergens in 0.1%. Complete blood counts showed different degrees of anemia in 363 animals (24.2%) and of these, 169 were RLB-positive for at least one pathogen. Among the ticks that were collected from the cattle, the following species were identified: Rhipicephalus bursa, Ixodes ricinus, Hyalomma marginatum, Boophilus annulatus, Dermacentor marginatus and Haemaphysalis (sulcata, parva, inermis and punctata). The results obtained confirmed the spread of endemic tick-borne pathogens in the regions studied. PMID:24614604

Retrospective study of hemoparasites in cattle in southern Italy by reverse line blot hybridization.

PubMed

Ceci, Luigi; Iarussi, Fabrizio; Greco, Beatrice; Lacinio, Rosanna; Fornelli, Stefania; Carelli, Grazia

2014-06-01

Tick-borne diseases are widespread in tropical and temperate regions and are responsible for important economic losses in those areas. In order to assess the presence and prevalence of various pathogens in southern Italy, we retrospectively analyzed cattle blood samples collected for a previous study in 2000 using reverse line blot (RLB) hybridization. The study had been carried out in three regions of southern Italy on 1,500 randomly selected and apparently healthy adult cattle. RLB showed that 43.7% of the cattle were positive for nine different species of hemoparasites with either a single infection or a mixed infection. Theileria buffeli was the most common species found, being present in 27.3% of the animals, followed by Anaplasma marginale in 18.1%, Anaplasma centrale in 13.8%, Babesia bigemina and Anaplasma bovis in 4.2%, Anaplasma phagocytophilum in 1.7%, Babesia bovis in 1.6%, Babesia major in 0.2% and Babesia divergens in 0.1%. Complete blood counts showed different degrees of anemia in 363 animals (24.2%) and of these, 169 were RLB-positive for at least one pathogen. Among the ticks that were collected from the cattle, the following species were identified: Rhipicephalus bursa, Ixodes ricinus, Hyalomma marginatum, Boophilus annulatus, Dermacentor marginatus and Haemaphysalis (sulcata, parva, inermis and punctata). The results obtained confirmed the spread of endemic tick-borne pathogens in the regions studied.

The Depression Anxiety Stress Scales-21 (DASS-21): further examination of dimensions, scale reliability, and correlates.

PubMed

Osman, Augustine; Wong, Jane L; Bagge, Courtney L; Freedenthal, Stacey; Gutierrez, Peter M; Lozano, Gregorio

2012-12-01

We conducted two studies to examine the dimensions, internal consistency reliability estimates, and potential correlates of the Depression Anxiety Stress Scales-21 (DASS-21; Lovibond & Lovibond, 1995). Participants in Study 1 included 887 undergraduate students (363 men and 524 women, aged 18 to 35 years; mean [M] age = 19.46, standard deviation [SD] = 2.17) recruited from two public universities to assess the specificity of the individual DASS-21 items and to evaluate estimates of internal consistency reliability. Participants in a follow-up study (Study 2) included 410 students (168 men and 242 women, aged 18 to 47 years; M age = 19.65, SD = 2.88) recruited from the same universities to further assess factorial validity and to evaluate potential correlates of the original DASS-21 total and scale scores. Item bifactor and confirmatory factor analyses revealed that a general factor accounted for the greatest proportion of common variance in the DASS-21 item scores (Study 1). In Study 2, the fit statistics showed good fit for the bifactor model. In addition, the DASS-21 total scale score correlated more highly with scores on a measure of mixed depression and anxiety than with scores on the proposed specific scales of depression or anxiety. Coefficient omega estimates for the DASS-21 scale scores were good. Further investigations of the bifactor structure and psychometric properties of the DASS-21, specifically its incremental and discriminant validity, using known clinical groups are needed. © 2012 Wiley Periodicals, Inc.

77 FR 7129 - Certain Pasta From Italy: Final Results of the 2009 Countervailing Duty Administrative Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-10

... DEPARTMENT OF COMMERCE International Trade Administration [C-475-819] Certain Pasta From Italy... review of the countervailing duty order on certain pasta from Italy for the period January 1, 2009... preliminary results of this review. See Certain Pasta From Italy: Preliminary Results of the 14th (2009...

78 FR 57129 - Certain Pasta From Italy and Turkey: Continuation of Antidumping and Countervailing Duty Orders

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-17

...-806] Certain Pasta From Italy and Turkey: Continuation of Antidumping and Countervailing Duty Orders... antidumping duty (AD) orders on certain pasta from Italy and Turkey would likely lead to continuation or recurrence of dumping, that revocation of the countervailing duty (CVD) orders on certain pasta from Italy...

78 FR 49256 - Certain Pasta From Italy: Preliminary Results of the Countervailing Duty Administrative Review; 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-13

... DEPARTMENT OF COMMERCE International Trade Administration [C-475-819] Certain Pasta From Italy...'') is conducting an administrative review of the countervailing duty order on certain pasta from Italy... The scope of the order consists of certain pasta from Italy. The merchandise subject to the order is...

75 FR 56992 - Certain Pasta From Italy: Notice of Initiation of Changed Circumstances Review and Consideration...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-17

... DEPARTMENT OF COMMERCE International Trade Administration [C-475-819] Certain Pasta From Italy..., in part, the countervailing duty order on certain pasta from Italy with respect to gluten-free pasta... published in the Federal Register the countervailing duty order on pasta from Italy. See Notice of...

The Valle di Manche section (Calabria, Southern Italy): A high resolution record of the Early-Middle Pleistocene transition (MIS 21-MIS 19) in the Central Mediterranean

NASA Astrophysics Data System (ADS)

Capraro, Luca; Ferretti, Patrizia; Macrì, Patrizia; Scarponi, Daniele; Tateo, Fabio; Fornaciari, Eliana; Bellini, Giulia; Dalan, Giorgia

2017-06-01

The on-land marine Valle di Manche section (Crotone Basin, Calabria, Southern Italy), one of the candidates to host the GSSP of the Middle Pleistocene (;Ionian;) Stage, preserves a manifold record of independent chronological, paleoclimatic and stratigraphic proxies that permit a straightforward correlation with marine and terrestrial reference records at the global scale. In particular, the section holds an excellent record of the Matuyama-Brunhes magnetic reversal, which occurs in the midst of Marine Isotope Stage (MIS) 19. We report on a complete revision of the section that improves dramatically the available dataset, especially in the stratigraphic interval straddling the Lower-Middle Pleistocene boundary. Our benthic δ18O record provides evidence that the Matuyama-Brunhes transition, the stratigraphic position of which is marked by a prominent tephra (the ;Pitagora ash;), occurred during full MIS 19, in agreement with many records worldwide. We obtained an age of 786.9 ± 5 ka for the Matuyama-Brunhes magnetic reversal and pinpointed the paleomagnetic transition of to a 3 cm-thick interval, indicating that the event was very fast. Since the section fulfills all the requirements to host the GSSP of the Ionian Stage, we propose that the boundary should be placed at the base of the ;Pitagora ash;, ca. 12.5 cm below the midpoint of the Matuyama-Brunhes reversal.

The Olympus satellite and satellite direct broadcasting in Italy

NASA Astrophysics Data System (ADS)

Castelli, E.; Tirro, S.

Plans for the development of DBS-TV technology in Italy are discussed from the perspective of the Italian electronics industry, with an emphasis on experimental broadcasts using the Olympus satellite channel assigned to Italy by ESA. Consideration is given to the operating characteristics of PAL, MAC-C, MAC-D2, extended-MAC, and MUSE color-TV systems and their compatibility with DBS; the planned availability of TV channels on Olympus-type and Italsat-type satellites; individual, community, and CATV reception of DBS signals; the projected growth of the DBS audience in Italy, the UK, and the FRG by 1999; and the potential Italian market for satellite receivers and antennas. The need for prompt completion and evaluation of the Olympus experiments and antennas. The need for prompt completion and evaluation of the Olympus experiments (beginning in 1987) and selection of the systems to be implemented, so that the industry can supply the home equipment required on time, is stressed. Tables of numerical data and maps of the Olympus coverage areas are provided.

76 FR 76937 - Certain Pasta From Italy: Notice of Final Results of the Fourteenth Antidumping Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-09

... DEPARTMENT OF COMMERCE International Trade Administration [A-475-818] Certain Pasta From Italy... review for the antidumping duty order on certain pasta from Italy.\\1\\ The review covers two manufacturers... (``POR'') is July 1, 2009, through June 30, 2010. \\1\\ See Certain Pasta from Italy: Notice of Preliminary...

77 FR 46377 - Certain Pasta From Italy: Notice of Preliminary Results of Antidumping Duty Administrative Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-03

... DEPARTMENT OF COMMERCE International Trade Administration [A-475-818] Certain Pasta From Italy... certain pasta (``pasta'') from Italy for the period of review (``POR'') July 1, 2010, through June 30... antidumping duty order on pasta from Italy.\\1\\ On July 1, 2011, the Department published a notice of...

75 FR 81308 - Stainless Steel Sheet And Strip From Germany, Italy, Japan, Korea, Mexico, And Taiwan

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-27

...)] Stainless Steel Sheet And Strip From Germany, Italy, Japan, Korea, Mexico, And Taiwan AGENCY: United States... and strip from Germany, Italy, Japan, Korea, Mexico, and Taiwan. SUMMARY: The Commission hereby gives... strip from Germany, Italy, Japan, Korea, Mexico, and Taiwan would be likely to lead to continuation or...

75 FR 59744 - Stainless Steel Sheet and Strip From Germany, Italy, Japan, Korea, Mexico, and Taiwan

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-28

...)] Stainless Steel Sheet and Strip From Germany, Italy, Japan, Korea, Mexico, and Taiwan AGENCY: United States... duty orders on stainless steel sheet and strip from Germany, Italy, Japan, Korea, Mexico, and Taiwan... stainless steel sheet and strip from Germany, Italy, Japan, Korea, Mexico, and Taiwan would be likely to...

Prenatal diagnosis of i(18q) and dup(18q) cases by quantitative fluorescent PCR

PubMed Central

Castro-Volio, Isabel; Ortíz-Morales, Fernando; Valle-Bourrouet, Luisa; Malespín-Bendaña, Wendy

2013-01-01

Particular sonographic fetal malformations are common in chromosome 18 aberrations, requiring invasive prenatal tests to confirm the diagnosis. Karyotyping is the gold standard assay in these cases, although it is a high complexity, expensive and approximately 2 weeks turnaround time test. On the contrary, quantitative fluorescent PCR is considered an accurate, simple, low cost and rapid assay, particularly useful for the diagnosis of aneuploidies of chromosomes 13, 18 and 21 and for the detection of maternal cell contamination of the sample. Clinical presentation of two cases of rare chromosome 18 defects, diagnosed using both techniques. One case was an isochromosome and the other was a partial duplication. Quantitative fluorescent PCR was an invaluable tool for the cytogenetics laboratory PMID:24045756

Italy: A Study of the Educational System of Italy and a Guide to the Academic Placement of Students from Italy in Educational Institutions of the United States.

ERIC Educational Resources Information Center

Capobianco, Joseph P.

The educational system of Italy is described, and placement recommendations concerning students who want to study in the United States are presented. After a description of preschool, elementary, and middle school education, the different types of upper-secondary education system are considered (i.e., the lyceums, teacher training, and technical…

38 CFR 21.7310 - Civil rights.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Civil rights. 21.7310... Bill-Active Duty) Administrative § 21.7310 Civil rights. (a) Delegation of authority concerning Federal... her jurisdiction. See part 18 of this chapter. These equal opportunity laws are: (1) Title VI, Civil...

38 CFR 21.7310 - Civil rights.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Civil rights. 21.7310... Bill-Active Duty) Administrative § 21.7310 Civil rights. (a) Delegation of authority concerning Federal... her jurisdiction. See part 18 of this chapter. These equal opportunity laws are: (1) Title VI, Civil...

38 CFR 21.7310 - Civil rights.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Civil rights. 21.7310... Bill-Active Duty) Administrative § 21.7310 Civil rights. (a) Delegation of authority concerning Federal... her jurisdiction. See part 18 of this chapter. These equal opportunity laws are: (1) Title VI, Civil...

38 CFR 21.7310 - Civil rights.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Civil rights. 21.7310... Bill-Active Duty) Administrative § 21.7310 Civil rights. (a) Delegation of authority concerning Federal... her jurisdiction. See part 18 of this chapter. These equal opportunity laws are: (1) Title VI, Civil...

38 CFR 21.7310 - Civil rights.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Civil rights. 21.7310... Bill-Active Duty) Administrative § 21.7310 Civil rights. (a) Delegation of authority concerning Federal... her jurisdiction. See part 18 of this chapter. These equal opportunity laws are: (1) Title VI, Civil...

Spectroscopic, microchemical and petrographic analyses of plasters from ancient buildings in Lamezia Terme (Calabria, Southern Italy)

NASA Astrophysics Data System (ADS)

De Luca, Raffaella; Gigliotti, Valentina; Panarello, Mario; Bloise, Andrea; Crisci, Gino M.; Miriello, Domenico

2016-01-01

This work shows the results of the spectroscopic, microchemical and petrographic study carried out on six plasters coming from three important residential buildings of the 18th century, located in Lamezia Terme (Catanzaro, Southern Italy). To study the provenance of the raw materials used to make the plasters, one sample of limestone and two samples of sand were also collected from the quarries near Lamezia Terme and compared with the historical plasters. Samples were studied by polarized optical microscopy (OM), X-ray powder diffraction (XRPD), scanning electron microscopy (SEM) with energy dispersive X-ray spectroscopy (EDS) and Raman spectroscopy. The results of these analyses allowed to determine the mineralogical, petrographical and chemical characteristics of the plasters, identify the pigments used for their coloration and provide useful information about the building techniques, the raw materials employed and the production technology of plasters during the 18th century in Lamezia Terme. SEM-EDS microanalysis also revealed the presence of gold and silver on the surface of two samples.

Observation of Quantum Beating in rb at 2.1 THz and 18.2 THz: Long-Range Rb^{*}-Rb Interactions.

NASA Astrophysics Data System (ADS)

Goldshlag, William; Ricconi, Brian J.; Eden, J. Gary

2017-06-01

The interaction of Rb 7s ^{2}S_{1/2}, 5d ^{2}D_{3/2,5/2} and 5p ^{2}P_{3/2} atoms with the background species at long range (100-1000Å) has been observed by pump-probe ultrafast laser spectroscopy. Parametric four-wave mixing in Rb vapor with pairs of 50-70 fs pulses produces coherent Rb 6P-5S emission at 420 nm that is modulated by Rb quantum beating. The two dominant beating frequencies are 18.2 THz and 2.07 THz, corresponding to quantum beating between 7S and 5D states and to the (5D-5P_{3/2})-(5P_{3/2}-5S) defect, respectively. Analysis of Rabi oscillations in these pump-probe experiments allows for the mean interaction energy at long range to be determined. The figure shows Fourier transform spectra of representative Rabi oscillation waveforms. The waveform and spectrum at left illustrate quantum beating in Rb at 2.1 THz. The spectrum at right is dominated by the 18.2 THz frequency component generated by 7S-5D beating in Rb. Insets show respective temporal behaviors of the 6P-5S line near the coherent transient (zero interpulse delay).

The family in Italy: cultural changes and implications for treatment.

PubMed

Luciano, Mario; Sampogna, Gaia; del Vecchio, Valeria; Giacco, Domenico; Mulè, Alice; de Rosa, Corrado; Fiorillo, Andrea; Maj, Mario

2012-04-01

In Italy family is characterized by strong ties and is based on mutual aid of all its members. In the last 20 years, the structure of families has been significantly influenced by demographic, economic and professional changes, determining a transition from a patriarchal to a nuclear family model, with a higher number of single-parent families, single-person households, childless couples, same-sex couples. However, this transition has been slower than that occurring in other countries, probably as an ongoing impact of prevalent Catholic ideology. Major demographic changes in Italian families include, 1) a decrease in the number of marriages, delays in getting married and an high number of civil ceremonies, 2) a reduced birth rate; Italy is becoming one of the European countries with lowest growth rate, and with an increasing number of births out of wedlock, 3) an increased marital instability, with a constantly growing number of legal separations. Like many countries, relatives in Italy are highly involved in the care of patients with physical and mental disorders. There are a number of psychosocial interventions used in Italy including the 'Milan Systemic Approach' and family psycho-educational interventions. However, there are difficulties in implementing these interventions which are highlighted in this paper. We recommend research strategies to identify the best options to involve families in the care of mentally ill patients and to adequately support them.

Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women

PubMed Central

2012-01-01

Background In 2009 the Uterine Bleeding and Pain Women's Research Study (UBP-WRS) was conducted interviewing 21,479 women across 8 countries in order to gain patient-based prevalence data on uterine pain and bleeding indications and investigate uterine symptoms and women's treatment experiences. This article shows relevant results of the study for the indication uterine fibroids providing data on self-reported prevalence, symptomatology and management of uterine fibroids. Methods 2,500 women (USA: 4,500 women) in each country (Brazil, Canada, France, Germany, Italy, South Korea, the UK, the USA) completed an online survey. Women included were in their reproductive age (age group 15-49 years; USA: 18-49 years) and had ever experienced menstrual bleedings. Quotas were applied for age, region, level of education and household income of respondents. Variables have been analyzed descriptively and exploratory statistical tests have been performed. Results The self-reported prevalence of uterine fibroids ranged from 4.5% (UK) to 9.8% (Italy), reaching 9.4% (UK) to 17.8% (Italy) in the age group of 40-49 years. Women with a diagnosis of uterine fibroids reported significantly more often about bleeding symptoms than women without a diagnosis: heavy bleedings (59.8% vs. 37.4%), prolonged bleedings (37.3% vs. 15.6%), bleeding between periods (33.3% vs. 13.5%), frequent periods (28.4% vs. 15.2%), irregular and predictable periods (36.3% vs. 23.9%). Furthermore women with diagnosed uterine fibroids reported significantly more often about the following pain symptoms: pressure on the bladder (32.6% vs. 15.0%), chronic pelvic pain (14.5% vs. 2.9%), painful sexual intercourse (23.5% vs. 9.1%) and pain occurring mid-cycle, after and during menstrual bleeding (31.3%, 16.7%, 59.7%, vs. 17.1%, 6.4%, 52.0%). 53.7% of women reported that their symptoms had a negative impact on their life in the last 12 month, influencing their sexual life (42.9%), performance at work (27.7%) and

Antigenic and molecular characterization of isolates of the Italy 02 infectious bronchitis virus genotype.

PubMed

Dolz, Roser; Pujols, Joan; Ordóñez, German; Porta, Ramon; Majó, Natàlia

2006-04-01

As part of an epidemiological surveillance of infectious bronchitis virus (IBV) in Spain, four Spanish field isolates showed high S1 spike sequence similarities with an IBV sequence from the GenBank database named Italy 02. Given that little was known about this new emergent IBV strain we have characterized the four isolates by sequencing the entire S1 part of the spike protein gene and have compared them with many reference IBV serotypes. In addition, cross-virus neutralization assays were conducted with the main IBV serotypes present in Europe. The four Spanish field strains and the Italy 02 S1 sequence from the NCBI database were established as a new genotype that showed maximum amino acid identities with the 4/91 serotype (81.7% to 83.7%), the D274 group that included D207, D274 and D3896 strains (79.8% to 81.7%), and the B1648 serotype (79.3% to 80%). Furthermore, on the basis of these results, it was demonstrated that the Italy 02 genotype had been circulating in Spain since as early as 1997. Based on the average ratio of synonymous:non-synonymous (dS/dN) amino acid substitutions within Italy 02 sequences, no positive selection pressures were related with changes observed in the S1 gene. Moreover, phylogenetic analysis of the S1 gene suggested that the Italy 02 genotype has undergone a recombination event. Virus neutralization assays demonstrated that little antigenic relatedness (less than 35%) exists between Italy 02 and some of the reference IBV serotypes, and indicated that Italy 02 is likely to be a new serotype.

The Earth's magnetic field in Italy during the Neolithic period: New data from the Early Neolithic site of Portonovo (Marche, Italy)

NASA Astrophysics Data System (ADS)

Tema, Evdokia; Ferrara, Enzo; Camps, Pierre; Conati Barbaro, Cecilia; Spatafora, Simone; Carvallo, Claire; Poidras, Thierry

2016-08-01

We present new, full geomagnetic field vector results from three Neolithic ovens discovered at the archaeological site of Portonovo (Marche, Italy). The discovered structures are a rare example of very well preserved underground ovens from the Early Neolithic period. Standard thermal demagnetization procedures were used to isolate the direction of the Characteristic Remanent Magnetization acquired by the baked clay during the ovens' last firing. The corresponding archaeointensities were determined by the multi-specimen procedure (MSP-DSC) and show a clear intensity low during the Neolithic period. Both directional and intensity results are of high quality, offering the first contribution of full geomagnetic field vector data for this period in Italy. The new data are compared with other contemporaneous data from Europe and with global geomagnetic field models. Independent archaeomagnetic dating of the three ovens was also performed by means of the SCHA.DIF.14k model. The obtained results are in excellent agreement with available radiocarbon dates and confirm that all ovens belong to the Neolithic. These new data importantly enrich our knowledge of the geomagnetic field during the Neolithic period that is poorly documented by data, not only in Italy but also in the whole of Europe and show that archaeomagnetic dating can provide precise results even for prehistoric periods.

CLIL in Italy: A General Overview

ERIC Educational Resources Information Center

Cinganotto, Letizia

2016-01-01

CLIL (Content and Language Integrated Learning) was introduced in the Italian school system in 2003 through a Reform Law, which made it mandatory for upper secondary schools. This paper is aimed at describing the most important steps of this innovation, with the relevant implications for policymakers, teachers and students. Italy's CLIL mandate is…

Education for Older People in Italy

ERIC Educational Resources Information Center

Principi, Andrea; Lamura, Giovanni

2009-01-01

This article provides information on trends in formal and informal adult education in Italy, with a particular focus on the older learners (over 65). Main providers, programs, objectives/motivations, and financial and legal framework are described. In general, over-65-year-old people were found to be underrepresented in participation. They were…

78 FR 48146 - Certain Pasta From Italy: Antidumping Duty Administrative Review; 2011-2012

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-07

... DEPARTMENT OF COMMERCE International Trade Administration [A-475-818] Certain Pasta From Italy... certain pasta (pasta) from Italy,\\1\\ covering the period July 1, 2011, through June 30, 2012. The review... e Pastificio and its affiliates Rummo S.p.A., Lenta Lavorazione, and Pasta Castiglioni (collectively...

Biodistribution and radiation dosimetry of 18F-CP-18, a potential apoptosis imaging agent, as determined from PET/CT scans in healthy volunteers.

PubMed

Doss, Mohan; Kolb, Hartmuth C; Walsh, Joseph C; Mocharla, Vani; Fan, Hong; Chaudhary, Ashok; Zhu, Zhihong; Alpaugh, R Katherine; Lango, Miriam N; Yu, Jian Q

2013-12-01

(18)F-CP-18, or (18S,21S,24S,27S,30S)-27-(2-carboxyethyl)-21-(carboxymethyl)-30-((2S,3R,4R,5R,6S)-6-((2-(4-(3-F18-fluoropropyl)-1H-1,2,3-triazol-1-yl)acetamido)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxamido)-24-isopropyl-18-methyl-17,20,23,26,29-pentaoxo-4,7,10,13-tetraoxa-16,19,22,25,28-pentaazadotriacontane-1,32-dioic acid, is being evaluated as a tissue apoptosis marker for PET imaging. The purpose of this study was to determine the biodistribution and estimate the normal-organ radiation-absorbed doses and effective dose from (18)F-CP-18. Successive whole-body PET/CT scans were obtained at approximately 7, 45, 90, 130, and 170 min after intravenous injection of (18)F-CP-18 in 7 healthy human volunteers. Blood samples and urine were collected between the PET/CT scans, and the biostability of (18)F-CP-18 was assessed using high-performance liquid chromatography. The PET scans were analyzed to determine the radiotracer uptake in different organs. OLINDA/EXM software was used to calculate human radiation doses based on the biodistribution of the tracer. (18)F-CP-18 was 54% intact in human blood at 135 min after injection. The tracer cleared rapidly from the blood pool with a half-life of approximately 30 min. Relatively high (18)F-CP-18 uptake was observed in the kidneys and bladder, with diffuse uptake in the liver and heart. The mean standardized uptake values (SUVs) in the bladder, kidneys, heart, and liver at around 50 min after injection were approximately 65, 6, 1.5, and 1.5, respectively. The calculated effective dose was 38 ± 4 μSv/MBq, with the urinary bladder wall having the highest absorbed dose at 536 ± 61 μGy/MBq using a 4.8-h bladder-voiding interval for the male phantom. For a 1-h voiding interval, these doses were reduced to 15 ± 2 μSv/MBq and 142 ± 15 μGy/MBq, respectively. For a typical injected activity of 555 MBq, the effective dose would be 21.1 ± 2.2 mSv for the 4.8-h interval, reduced to 8.3 ± 1.1 mSv for the 1-h interval

Dispersant approval procedures in France and Italy: A comparative ecotoxicity study.

PubMed

Manfra, Loredana; Tornambè, Andrea; Guyomarch, Julien; Le Guerrogue, Pascale; Kerambrun, Loïc; Rotini, Alice; Savorelli, Federica; Onorati, Fulvio; Magaletti, Erika

2017-09-01

A research project has been performed to the request of the RAMOGE Executive Secretariat to identify differences between dispersant approval procedures in France and Italy and propose ways to harmonize them. A collaborative study has been conducted by CEDRE (Centre of Documentation, Research and Experimentation on Accidental Water Pollution) and ISPRA (Italian Institute for Environmental Protection and Research) to: a) compare current approval procedures in Italy and France with identification of differences and commonalities; b) carry out toxicity tests using both procedures on two selected dispersants; c) propose a common approach between Italy and France. The results showed that, because of the differences in ecotoxicological tests and in the evaluation criteria used, the outcomes on the same products could be different in Italy and in France. Both tested dispersants met the French requirements for approval (LC 50 ≥ 10 times reference toxicant), while only one dispersant met the Italian approval criterion (EC 50 > 10mg/L). A possible way of harmonizing the approval procedures could be to increase the number of test organisms in the French procedure, which currently only uses one crustacean species. Furthermore, a common criterion for toxicity assessment should be discussed and agreed. Copyright © 2017. Published by Elsevier Inc.

Forest fires in Italy: An econometric analysis of major driving factors

NASA Astrophysics Data System (ADS)

Michetti, Melania; Pinar, Mehmet

2013-04-01

Despite the relevant fire risk to which Italy is subject from north to south, very few analysis focus on this area. This article investigates the causes of forest fires frequency and intensity in Italy during the first decade of the XXI century. The dynamical aspects of fire danger are explored through the use of panel data techniques which fully capture the impacts on forest fires of changes in both socio-economic and climatic conditions. Italy is treated as a unique region in a first model specification, while it is then split into 3 geographical areas (north, centre, and south) to capture locally specific aspects. Two different dependent variables are alternatively employed and a number of ad hoc tests are performed to corroborate the robustness of our estimates. Results highlight the importance of considering the fire situation separately for the northern, central, and southern parts of Italy. While the presence of railway networks positively affects fire risk, the impact of livestock depends on its specific composition. Favourable effects in fire reduction are represented by the increase in education levels (north and centre) and touristic flows (north and south), and by the containment of illegal activities (south). Weather patterns appear to be important determinants all over the Italian peninsula.

78 FR 54635 - Notice of Intent To Prepare an Environmental Impact Statement for EA-18G Growler Airfield...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... the potential environmental effects associated with the introduction of two additional EA-18G Growler... CONTACT: EA-18G EIS Project Manager (Code EV21/ SS); Naval Facilities Engineering Command (NAVFAC... request should be submitted to: EA-18G EIS Project Manager (Code EV21/SS); Naval Facilities Engineering...

Primary care units in Emilia-Romagna, Italy: an assessment of organizational culture.

PubMed

Pracilio, Valerie P; Keith, Scott W; McAna, John; Rossi, Giuseppina; Brianti, Ettore; Fabi, Massimo; Maio, Vittorio

2014-01-01

This study investigates the organizational culture and associated characteristics of the newly established primary care units (PCUs)-collaborative teams of general practitioners (GPs) who provide patients with integrated health care services-in the Emilia-Romagna Region (RER), Italy. A survey instrument covering 6 cultural dimensions was administered to all 301 GPs in 21 PCUs in the Local Health Authority (LHA) of Parma, RER; the response rate was 79.1%. Management style, organizational trust, and collegiality proved to be more important aspects of PCU organizational culture than information sharing, quality, and cohesiveness. Cultural dimension scores were positively associated with certain characteristics of the PCUs including larger PCU size and greater proportion of older GPs. The presence of female GPs in the PCUs had a negative impact on collegiality, organizational trust, and quality. Feedback collected through this assessment will be useful to the RER and LHAs for evaluating and guiding improvements in the PCUs. © 2013 by the American College of Medical Quality.

An Italian peculiarity? Psychoanalysis, modernization and the sociology of consumption in 1960s Italy.

PubMed

Pasqualini, Mauro

2017-11-01

Psychoanalysis experienced a remarkable boom in 1960s Italy. One of the areas where psychoanalytic theory disseminated was the world of marketing and the sociology of consumption. Based on the case of the sociologist Francesco Alberoni, we can examine the impact of the theories of Melanie Klein for understanding the behavior of consumers. Similarly, Alberoni's work shows the concerns and uncertainties on the social modernization of Italy, and also raises questions on the specificities of the growing importance of psychoanalysis in Italy in the 1960s.

76 FR 35910 - Brass Sheet and Strip From France, Germany, Italy, and Japan; Notice of Commission Determinations...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

...)] Brass Sheet and Strip From France, Germany, Italy, and Japan; Notice of Commission Determinations To..., Germany, Italy, and Japan AGENCY: United States International Trade Commission. ACTION: Notice. SUMMARY... duty orders on brass sheet and strip from France, Germany, Italy, and Japan would be likely to lead to...

78 FR 9937 - Certain Pasta From Italy and Turkey Scheduling of Full Five-Year Reviews Concerning the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

...)] Certain Pasta From Italy and Turkey Scheduling of Full Five-Year Reviews Concerning the Countervailing and Antidumping Duty Orders on Certain Pasta From Italy and Turkey AGENCY: United States International Trade... whether revocation of the countervailing and antidumping duty orders on certain pasta from Italy and...

78 FR 693 - Certain Pasta From Italy: Final Results of the Expedited Third Sunset Review of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-04

... DEPARTMENT OF COMMERCE International Trade Administration [C-475-819] Certain Pasta From Italy... Sunset Review of the countervailing duty order on certain pasta from Italy. The Department finds that... pasta from Italy was published on July 24, 1996. See Notice of Countervailing Duty Order and Amended...

Astronomical calibration of the middle Eocene Contessa Highway section (Gubbio, Italy)

NASA Astrophysics Data System (ADS)

Jovane, Luigi; Sprovieri, Mario; Coccioni, Rodolfo; Florindo, Fabio; Marsili, Andrea; Laskar, Jacques

2010-09-01

The Eocene climatic system experienced an important transition from warm Paleocene greenhouse to icehouse Oligocene conditions. This transition could first appear as a long-term cooling trend but, at an up-close look, this period is a complex combination of climatic events and, for most of them, causes and consequences are still not fully characterized. In this context, a study has been carried out on the middle Eocene sedimentary succession of the Contessa Highway section, central Italy, which is proposed as the Global Stratotype Section and Point (GSSP) for the Lutetian/Bartonian boundary at the top of the Chron 19n, with an astronomically calibrated age of 41.23 Ma. Through a cyclostratigraphic analysis of the rhythmic sedimentary alternations and combination with the results of time series analysis of the proxy record, we provide an orbital tuning of the middle Eocene and astronomical calibration of the bio-magnetostratigraphic events (particularly for the C19n/C18r Chron boundary) recognized at the Contessa Highway section.

Free-lance nursing in Italy.

PubMed

Galli, E; Lindsay, J S

1993-01-01

In 1987 Registered Nurses Ernesta 'Tina' Galli and Joanne Lindsay embarked on a unique venture--a private agency* organized and run by nurses that engages free-lance nurses to fill the need for nursing assistance both at home and in public and private institutions. The response has been overwhelming. Today they have branches throughout Italy and have expanded their services to include research and primary health care. Below, their story.

Systematic detection and classification of earthquake clusters in Italy

NASA Astrophysics Data System (ADS)

Poli, P.; Ben-Zion, Y.; Zaliapin, I. V.

2017-12-01

We perform a systematic analysis of spatio-temporal clustering of 2007-2017 earthquakes in Italy with magnitudes m>3. The study employs the nearest-neighbor approach of Zaliapin and Ben-Zion [2013a, 2013b] with basic data-driven parameters. The results indicate that seismicity in Italy (an extensional tectonic regime) is dominated by clustered events, with smaller proportion of background events than in California. Evaluation of internal cluster properties allows separation of swarm-like from burst-like seismicity. This classification highlights a strong geographical coherence of cluster properties. Swarm-like seismicity are dominant in regions characterized by relatively slow deformation with possible elevated temperature and/or fluids (e.g. Alto Tiberina, Pollino), while burst-like seismicity are observed in crystalline tectonic regions (Alps and Calabrian Arc) and in Central Italy where moderate to large earthquakes are frequent (e.g. L'Aquila, Amatrice). To better assess the variation of seismicity style across Italy, we also perform a clustering analysis with region-specific parameters. This analysis highlights clear spatial changes of the threshold separating background and clustered seismicity, and permits better resolution of different clusters in specific geological regions. For example, a large proportion of repeaters is found in the Etna region as expected for volcanic-induced seismicity. A similar behavior is observed in the northern Apennines with high pore pressure associated with mantle degassing. The observed variations of earthquakes properties highlight shortcomings of practices using large-scale average seismic properties, and points to connections between seismicity and local properties of the lithosphere. The observations help to improve the understanding of the physics governing the occurrence of earthquakes in different regions.

State of the art of chronic spontaneous urticaria in Italy: a multicentre survey to evaluate physicians’ and patients’ perspectives

PubMed Central

Rimoldi, Marco; Rossi, Oliviero; Rota, Nadia

2016-01-01

Objective To assess the clinical status of chronic spontaneous urticaria (CSU) and understand treatment approaches in Italy through specialists who treat CSU (dermatologists and allergy specialists) and CSU patients' experience. Design Multicentre survey. Setting Online structured questionnaires (one for physicians and one for patients). Participants Physicians and patients with CSU in Italy. Interventions None. Primary/secondary outcomes Physician and patient attitudes/experiences. Results Survey results from 160 allergy and 160 dermatology specialists show that specialists see a median of 40 (IQR 20–80) patients with CSU/year. While most specialists (56%) know the CSU guidelines, only 27% use them regularly (36% of allergy specialists vs 18% of dermatologists). This is reflected in treatment choices with differences between physicians who use guidelines regularly and those who do not: 91.6% vs 71.7% choose standard-dose, non-sedating antihistamines as first-line treatment; 85.9% vs 56.0% select up-dosing for second-line treatment and 65.3% vs 37.2% add leukotriene receptor antagonists or H2-antihistamines as third-line treatment. The diaries from 1385 patients highlight that, regardless of treatment regimen, 29.4% of currently treated patients are refractory to therapy. Specialists aim to resolve symptoms and only 7.8% report improving quality of life (QoL) as a priority. Only 16.6% of specialists are familiar with and use the Urticaria Activity Score while 46.9% do not know it. Overall, 537 patients with CSU were surveyed (median age 37 years, IQR 30–46; 44.3% men; median disease duration 5 years, IQR 3–20). Approximately 62% confirm that CSU negatively impacts their QoL. Patients also complain of difficulties in getting information and support: <5% of medical centres provide patient support services. Conclusions In Italy, the gap between guideline-based care and QoL-related needs in CSU patients affects treatment satisfaction. This information could

State of the art of chronic spontaneous urticaria in Italy: a multicentre survey to evaluate physicians' and patients' perspectives.

PubMed

Rimoldi, Marco; Rossi, Oliviero; Rota, Nadia

2016-10-14

To assess the clinical status of chronic spontaneous urticaria (CSU) and understand treatment approaches in Italy through specialists who treat CSU (dermatologists and allergy specialists) and CSU patients' experience. Multicentre survey. Online structured questionnaires (one for physicians and one for patients). Physicians and patients with CSU in Italy. None. Physician and patient attitudes/experiences. Survey results from 160 allergy and 160 dermatology specialists show that specialists see a median of 40 (IQR 20-80) patients with CSU/year. While most specialists (56%) know the CSU guidelines, only 27% use them regularly (36% of allergy specialists vs 18% of dermatologists). This is reflected in treatment choices with differences between physicians who use guidelines regularly and those who do not: 91.6% vs 71.7% choose standard-dose, non-sedating antihistamines as first-line treatment; 85.9% vs 56.0% select up-dosing for second-line treatment and 65.3% vs 37.2% add leukotriene receptor antagonists or H 2 -antihistamines as third-line treatment. The diaries from 1385 patients highlight that, regardless of treatment regimen, 29.4% of currently treated patients are refractory to therapy. Specialists aim to resolve symptoms and only 7.8% report improving quality of life (QoL) as a priority. Only 16.6% of specialists are familiar with and use the Urticaria Activity Score while 46.9% do not know it. Overall, 537 patients with CSU were surveyed (median age 37 years, IQR 30-46; 44.3% men; median disease duration 5 years, IQR 3-20). Approximately 62% confirm that CSU negatively impacts their QoL. Patients also complain of difficulties in getting information and support: <5% of medical centres provide patient support services. In Italy, the gap between guideline-based care and QoL-related needs in CSU patients affects treatment satisfaction. This information could be used to improve the management of CSU in Italy. Published by the BMJ Publishing Group Limited. For

76 FR 6601 - Certain Pasta From Italy: Notice of Amended Final Results of the Thirteenth Antidumping Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-07

... DEPARTMENT OF COMMERCE International Trade Administration [A-475-818] Certain Pasta From Italy... of the antidumping duty order on certain pasta from Italy for the period of review (POR) of July 1, 2008, through June 30, 2009. See Certain Pasta from Italy: Notice of Final Results of the Thirteenth...

75 FR 11116 - Certain Pasta from Italy: Notice of Amended Final Results of the Twelfth Antidumping Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-10

... DEPARTMENT OF COMMERCE International Trade Administration [A-475-818] Certain Pasta from Italy... certain pasta from Italy for the period of review (POR) of July 1, 2007, through June 30, 2008. See Certain Pasta from Italy: Notice of Final Results of the Twelfth Administrative Review, 75 FR 6352...

Large Human Outbreak of West Nile Virus Infection in North-Eastern Italy in 2012

PubMed Central

Barzon, Luisa; Pacenti, Monia; Franchin, Elisa; Pagni, Silvana; Lavezzo, Enrico; Squarzon, Laura; Martello, Thomas; Russo, Francesca; Nicoletti, Loredana; Rezza, Giovanni; Castilletti, Concetta; Capobianchi, Maria Rosaria; Salcuni, Pasquale; Cattai, Margherita; Cusinato, Riccardo; Palù, Giorgio

2013-01-01

Human cases of West Nile virus (WNV) disease have been reported in Italy since 2008. So far, most cases have been identified in north-eastern Italy, where, in 2012, the largest outbreak of WNV infection ever recorded in Italy occurred. Most cases of the 2012 outbreak were identified in the Veneto region, where a special surveillance plan for West Nile fever was in place. In this outbreak, 25 cases of West Nile neuroinvasive disease and 17 cases of fever were confirmed. In addition, 14 WNV RNA-positive blood donors were identified by screening of blood and organ donations and two cases of asymptomatic infection were diagnosed by active surveillance of subjects at risk of WNV exposure. Two cases of death due to WNND were reported. Molecular testing demonstrated the presence of WNV lineage 1 in all WNV RNA-positive patients and, in 15 cases, infection by the novel Livenza strain was ascertained. Surveillance in other Italian regions notified one case of neuroinvasive disease in the south of Italy and two cases in Sardinia. Integrated surveillance for WNV infection remains a public health priority in Italy and vector control activities have been strengthened in areas of WNV circulation. PMID:24284876

Import risk analysis of fruit from Spain to Italy.

PubMed

Pani, G; Molinu, M G; Venditti, T; Dore, A; Ladu, G; D'Hallewin, G

2012-01-01

The International trade has to ensure food security and preserve both human health and the diffusion of animal and plant diseases among different countries. While organic horticultural production and trade are regulated by global guidelines, no specific restrictions relay to conventional commodities and almost free import-export occurs among UE countries. Consequently, the safety characteristics of imported fresh crops have become an important issue. On the basis of these considerations, the aim of the present study is to monitor the epiphytic microflora (particularly yeasts and fungi) carried by fresh fruit, imported from Spain to Italy. Particular attention was given to pathogenic microrganisms and to natural antagonists. In addition, the resistance to a few postharvest fungicides was determined for the isolated strains and compared to the local ones. Apples, Citrus fruits, stone fruits, and persimmon fruit were sampled at arrival of the container from Spain at the wholesale market in Sassari (Italy), this to prevent fruit contamination by local strains of microrganisms. The isolation was performed by rinsing and shaking (30 min at 100 rpm) the fruit in a beaker with 500 mL of sterile water. After concentration (7.5 mL), 100 microl of the rinse water was plated on potato dextrose agar (PDA). Isolation of pure colonies was performed by multiple streaking on plates, until unicellular cultures were obtained. Fifty three microrganisms, mainly fungi and yeasts, have been isolated and assayed in vitro and in vivo. Pathogenic behavior of isolated fungi was tested on fruits artificially wounded and only 7 strains out of 18 isolates caused decay. The resistance to different concentrations of imazalil (IMZ), tiabendazolo and azoxystrobin were tested in vitro for the pathogenic isolates. All isolates were completely inhibited with 1000 ppm IMZ evidencing that no resistant strains were present on the imported fruit. Since the baseline resistance, found for all isolates, was

Photoemission study of absorption mechanisms in Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ, BaBiO3, and Nd1.85Ce0.15CuO4

NASA Astrophysics Data System (ADS)

Lindberg, P. A. P.; Shen, Z.-X.; Wells, B. O.; Dessau, D. S.; Ellis, W. P.; Borg, A.; Kang, J.-S.; Mitzi, D. B.; Lindau, I.; Spicer, W. E.; Kapitulnik, A.

1989-11-01

Photoemission measurements in the constant-final-state (absorption) mode were performed on three different classes of high-temperature superconductors Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ, BaBiO3, and Nd1.85Ce0.15CuO4 using synchrotron radiation from 20 to 200 eV. Absorption signals from all elements but Ce are identified. The results firmly show that the Bi 6s electrons are more delocalized in BaBiO3 than in Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ, in agreement with the results of band-structure calculations. Differences in the absorption signals due to O and Bi excitations between BaBiO3 and Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ are discussed. Delayed absorption onsets attributed to giant resonances (Ba 4d-->4f, La 4d-->4f, and Nd 4d-->4f transitions) are also reported.

Medical dominance in Italy: a partial decline.

PubMed

Tousijn, Willem

2002-09-01

In the last three decades, a number of changes in health systems has been challenging medical dominance in many countries. It has been widely debated whether the medical profession has been able to cope with these changes and maintain its power or, rather, has been deprofessionalised or proletarianised. In this paper, the effects of these changes in Italy are examined, by using a multi-dimensional concept of medical dominance. As a result of this analysis. medical dominance in Italy is depicted as declining on some dimensions while changing its nature on others. The final part of the paper discusses some current explanations of this trend and suggests that the transition to post-modern society and the "late modernity" argument (Giddens, 1990; The consequences of modernity, Polity Press, Cambridge; Beck, 1992; Risk society: towards a new modernity, Sage, London) may provide an entry into more adequate explanations.

Pericentric inversion of chromosome 18 in parents leading to a phenotypically normal child with segmental uniparental disomy 18.

PubMed

Kariminejad, Ariana; Kariminejad, Roxana; Moshtagh, Azadeh; Zanganeh, Maryam; Kariminejad, Mohammad Hassan; Neuenschwander, Stefan; Okoniewski, Michal; Wey, Eva; Schinzel, Albert; Baumer, Alessandra

2011-05-01

In this study, we report a familial inversion of chromosome 18, inv(18)(p11.31q21.33), in both members of a consanguineous couple. Their first child had inherited one balanced pericentric inversion along with a recombinant chromosome 18 resulting in dup(18q)/del(18p), and had mild dysmorphic features in the absence of mental and developmental retardation. The second child had received two recombinant chromosomes 18, from the mother a derivative chromosome 18 with dup(18p)/del(18q) and from the father a derivative chromosome 18 with dup(18q)/del(18p). The aberration was prenatally detected; however, as the two opposite aneuploidies were thought to compensate each other, the family decided to carry on with the pregnancy, knowing that uniparental disomy for the segments outside the inversion could have an adverse influence on the development of the child. Uniparental disomy was confirmed by SNP arrays. The child, who has been followed up until the age of 20 months, is healthy and normal. It seems to be the first reported case with two opposite recombinant chromosomes that compensate each other and lead to segmental uniparental disomy for two segments on the chromosome, one maternal and the other paternal.

76 FR 9072 - Sunshine Act Meeting Notice; February 18, 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-16

... TENNESSEE VALLEY AUTHORITY [Meeting No. 11-01] Sunshine Act Meeting Notice; February 18, 2011 The TVA Board of Directors will hold a public meeting on February 18, 2011, at the Tri-County Community College, 21 Campus Circle, Murphy, North Carolina, to consider the matters listed below. The public may...

Radioactivity in honey of the central Italy.

PubMed

Meli, Maria Assunta; Desideri, Donatella; Roselli, Carla; Feduzi, Laura; Benedetti, Claudio

2016-07-01

Natural radionuclides and (137)Cs in twenty seven honeys produced in a region of the Central Italy were determined by alpha ((235)U, (238)U, (210)Po, (232)Th and (228)Th) and gamma spectrometry ((137)Cs, (40)K, (226)Ra and (228)Ra). The study was carried out in order to estimate the background levels of natural ((40)K, (238)U and (232)Th and their progeny) and artificial radionuclides ((137)Cs) in various honey samples, as well as to compile a data base for radioactivity levels in that region. (40)K showed a mean activity of 28.1±23.0Bqkg(-1) with a range of 7.28-101Bqkg(-1). The mean of (210)Po activity resulted 0.40±0.46Bqkg(-1) with a range of 0.03-1.98Bqkg(-1). The mean of (238)U activity resulted 0.020±0.010Bqkg(-1). (226)Ra and (228)Ra resulted always <0.34 and <0.57Bqkg(-1) respectively, (235)U, (228)Th and (232)Th were always <0.007Bqkg(-1). (137)Cs resulted <0.10Bqkg(-1) in all samples. The committed effective doses due to (210)Po from ingestion of honey for infants, children and adults account for 0.002-5.13% of the natural radiation exposure in Italy. The honeys produced in Central Italy were of good quality in relation to the studied parameters, confirming the general image of a genuine and healthy food associated to this traditional products. Copyright © 2016 Elsevier Ltd. All rights reserved.

[Report on health status of residents in areas with industrial, mining or military sites in Sardinia, Italy].

PubMed

Biggeri, Annibale; Lagazio, Corrado; Catelan, Dolores; Pirastu, Roberta; Casson, Felice; Terracini, Benedetto

2006-01-01

, Oristano and Sassari) were greater than the difference between Sardinia and Italy. Remarkably enough, also death rates from lymphohaemopoietic tumours were more heterogeneous within Sardinia. Rates of hospital discharges in Sardinia showed a high variability, which is partly attributable to differences in the availability of both hospital beds and alternative forms of care. This heterogeneity must be taken into account in the interpretation of rates of hospital discharge. These were relatively high in some areas (Cagliari, Iglesias, Portoscuso, Tortolì) and low in others (Olbia, Porto Torres, Sassari). All the reported observed/expected ratios were based on material deprivation adjusted figures. All the estimated statistics were reported with 90% Confidence Interval. In 1997-2001, deaths from respiratory diseases were significantly in excess in males in Portoscuso (obs/exp 205/124.77) and in San Gavino (69/46.77). Deaths from pneumoconiosis were recorded sporadically, with the exception of Portoscuso, where the excess was impressive (obs/exp 112/30.46). SMRs for lung cancer in males ranged between 0.62 in Ottana and 1.22 in San Gavino, with statistically significant departure from expected values in Portoscuso and Sarroch (both with SMR significantly in excess in males: 1.24). In Porto Torres mortality from all causes was in significant excess in both sexes (SMRs 1.04 in males and 1.09 in females), for respiratory diseases (1.08 and 1.28), for diseases of the digestive system (1.13 and 1.21), for all cancers (1.04 and 1.09). Liver cancer deaths were also in excess in both sexes (SMRs 1.18 and 1.21). The latter finding is confirmed by incidence rates from the local cancer registry. Among industrial areas, Porto Torres was also the one with a stronger evidence of an excess of deaths from lymphohaemopoietic cancer in males (obs/exp 99/83.60) and females (73/68.20). These areas are characterized by statistically significant excesses of mortality in males, largely caused by

COMO: a numerical model for predicting furnace performance in axisymmetric geometries. Volume 1. Technical summary. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fiveland, W.A.; Oberjohn, W.J.; Cornelius, D.K.

1985-12-01

This report summarizes the work conducted during a 30-month contract with the United States Department of Energy (DOE) Pittsburgh Energy Technology Center (PETC). The general objective is to develop and verify a computer code capable of modeling the major aspects of pulverized coal combustion. Achieving this objective will lead to design methods applicable to industrial and utility furnaces. The combustion model (COMO) is based mainly on an existing Babcock and Wilcox (B and W) computer program. The model consists of a number of relatively independent modules that represent the major processes involved in pulverized coal combustion: flow, heterogeneous and homogeneousmore » chemical reaction, and heat transfer. As models are improved or as new ones are developed, this modular structure allows portions of the COMO model to be updated with minimal impact on the remainder of the program. The report consists of two volumes. This volume (Volume 1) contains a technical summary of the COMO model, results of predictions for gas phase combustion, pulverized coal combustion, and a detailed description of the COMO model. Volume 2 is the Users Guide for COMO and contains detailed instructions for preparing the input data and a description of the program output. Several example cases have been included to aid the user in usage of the computer program for pulverized coal applications. 66 refs., 41 figs., 21 tabs.« less

Accuracy of 18F-FDOPA Positron Emission Tomography and 18F-FET Positron Emission Tomography for Differentiating Radiation Necrosis from Brain Tumor Recurrence.

PubMed

Yu, Jun; Zheng, Jingwei; Xu, Weilin; Weng, Jiaqi; Gao, Liansheng; Tao, Li; Liang, Feng; Zhang, Jianmin

2018-06-01

Distinguishing radiation necrosis from brain tumor recurrence remains challenging. We performed a meta-analysis to assess the diagnostic accuracy of 2 different amino acid tracers used in positron emission tomography/computed tomography scans: 18 F-FDOPA (6-[18F]-fluoro-L-3,4-dihydroxyphenylalanine) and 18 F-FET (O-(2-18F-fluoroethyl)-L-tyrosine). We searched for studies in 3 databases: PubMed, Embase, and Chinese Biomedical databases. The data were extracted from eligible studies and then processed with heterogeneity test, threshold effect test, and calculations of sensitivity, specificity, and area under the summary receiver operating characteristic curve. Meta-regression and subgroup analyses were performed to explore the source of heterogeneity. A total of 48 studies ( 18 F-FDOPA, n = 21; 18 F-FET, n = 27) were included. Quantitative synthesis determined pooled weight values in the 18 F-FDOPA and 18 F-FET groups: sensitivity, 0.85 versus 0.82; specificity, 0.77 versus 0.80; diagnostic odds ratio, 21.7 versus 23.03; area under the curve (AUC) values, 0.8771 versus 0.8976 (P = 0.46). Moreover, the type of tumor was identified as the possible source of the significant heterogeneity (I 2  = 52%; P = 0.003) found in the 18 F-FDOPA group. In meta-regression and subgroup analyses, 18 F-FDOPA showed better diagnostic accuracy in patients with glioma compared with patients with brain metastases (AUC values, 0.9691 vs. 0.837; P < 0.01). 18 F-FDOPA also showed a significant advantage in the diagnosis of glioma recurrence compared with 18 F-FET (AUC values, 0.9691 vs. 0.9124; P = 0.015). Both 18 F-FDOPA and 18 F-FET exhibit moderate overall accuracy in diagnosing brain tumor recurrence from radiation necrosis. However, 18 F-FDOPA is more adept at diagnosing glioma recurrence compared with brain metastases, and it is more effective than 18 F-FET in diagnosing glioma recurrence. Copyright © 2018 Elsevier Inc. All rights reserved.

Urban air pollution and respiratory emergency visits at pediatric unit, Reggio Emilia, Italy.

PubMed

Bedeschi, Emanuela; Campari, Cinzia; Candela, Silvia; Collini, Giorgia; Caranci, Nicola; Frasca, Gabriella; Galassi, Claudia; Francesca, Gabriella; Vigotti, Maria Angela

2007-02-01

Short-term effects of air pollution on daily mortality and hospital admissions for respiratory causes are well documented. Few studies, however, explore the association between exposure to air pollution and daily emergency room visits for respiratory disorders, particularly in Italy and particularly among children as a susceptible population. A time-series analysis was conducted to explore the short-term association between air pollutants (PM10, total suspended particulates [TSP], NO2, SO2, CO, O3) and pediatric emergency room (ER) visits in a small city of northern Italy, Reggio Emilia, during the period 03/01/2001-03/31/2002. There were 1051 ER visits included in the study. Data were analyzed using generalized additive models (GAM), adjusting for various confounding variables, including temperature, humidity, and pollens (Graminaceae). The analyses were also stratified according to the nationality of children (Italians and foreigners). In single-pollutant models, the strongest associations were observed at lag 3 for a 10-microg/m3 increase of TSP (2.7% increase in ER, 95% CI 0.7-4.6) and PM10 (3.0% increase, 95% CI 0.4-5.7), and at lag 4 for a 10-microg/m3 increase of NO2 (11.0% increase in ER, 95% CI 3.6-18.8). At lag 3, the percentage increase in ER visits is similar for the 2 groups of children (Italians and foreigners) for TSP and PM10. The results of the study support the findings that air pollution is a relevant determinant of deterioration of respiratory health among children.

[Ten year cardio-cerebro-vascular mortality and morbidity in a Southern Italy cohort: the VIP Project data].

PubMed

Capuano, Vincenzo; Lamaida, Norman; Torre, Sergio; Capuano, Ernesto; Borrelli, Maria Immacolata; Capuano, Eduardo; Clarizia, Maria Maddalena; Capuano, Rocco; De Rosa, Carmela

2013-03-01

In Italy the mortality data were obtained almost exclusively from the data RENCAM (Name Causes of Death Register), while there are few prospective surveys. In order to assess whether there are particular epidemiological conditions in the geographical area of Mercato S. Severino, in Southern Italy, we have studied, and reassessed at ten years (1998/99 - 2008/09), a cohort of adult general population in a project of cardiovascular epidemiology and prevention. We calculated the rates of mortality and morbidity from cardiovascular events covering the period 1998/99 - 2008/09, in a cohort of 1200 persons (600 men and 600 women) aged 25 to 74 years. Data were standardized using the European standard population. Mortality from cardiovascular causes was 46.5% in men and 48.7% in women; it was mainly concentrated in the age group 65-74 years where it occurred on 62.9% of deaths in men and 66.7% in women. Regarding morbidity, the incidence of events to ten years of non-fatal myocardial infarction was 2.2% in men and of 1.8% in women. PTCA interventions to ten year have been 3.3% in men and 3.4% in women, the interventions of aorto-coronary bypass have been 2.4% and 0.5% for men and women respectively. While all major cardiovascular events have been more frequent in men, in women there was a higher incidence of stroke (1.6% vs 0.9%). Although by comparison with other European countries Italy is among the countries considered at low-risk of coronary heart disease, in Campania cardiovascular diseases reach higher rates than the rest of the country. Our results are in line with the literature data and confirm that cardiovascular diseases are a major public health problem. Local analysis to propose means to provide useful information for planning prevention interventions targeted to their own territory.

Retrospective Evaluation of the Long-Term CSEP-Italy Earthquake Forecasts

NASA Astrophysics Data System (ADS)

Werner, M. J.; Zechar, J. D.; Marzocchi, W.; Wiemer, S.

2010-12-01

On 1 August 2009, the global Collaboratory for the Study of Earthquake Predictability (CSEP) launched a prospective and comparative earthquake predictability experiment in Italy. The goal of the CSEP-Italy experiment is to test earthquake occurrence hypotheses that have been formalized as probabilistic earthquake forecasts over temporal scales that range from days to years. In the first round of forecast submissions, members of the CSEP-Italy Working Group presented eighteen five-year and ten-year earthquake forecasts to the European CSEP Testing Center at ETH Zurich. We considered the twelve time-independent earthquake forecasts among this set and evaluated them with respect to past seismicity data from two Italian earthquake catalogs. Here, we present the results of tests that measure the consistency of the forecasts with the past observations. Besides being an evaluation of the submitted time-independent forecasts, this exercise provided insight into a number of important issues in predictability experiments with regard to the specification of the forecasts, the performance of the tests, and the trade-off between the robustness of results and experiment duration.

Electoral democracy, revolutionary politics and political violence: the emergence of Fascism in Italy, 1920-21.

PubMed

Elazar, D S

2000-09-01

This study examines the determination of the Italian Fascists' extra-parliamentary, para-military, violent strategy. What were the effects of the socialists' political strategy, relying on electoral democracy, on the creation and strategy of the Fascist Action Squads? A comparison among Italy's 69 provinces, based on quantitative and qualitative historical evidence reveals a distinct pattern in the Fascists' violence. They attacked mainly provinces where the Socialists enjoyed the greatest electoral support. This pattern was a product of two historical processes: (a) the threat of the Socialist party to the landlords' economic and political hegemony, and (b) the landlords' tradition of militant anti-worker organization which culminated in their alliance with the Fascists. The Fascists' struggle for, and takeover of, political power was not an immanent historical necessity. It was first and foremost an anti-socialist reaction. It was shaped both 'from below', by the political power and radicalism of the PSI and the para-military capacity of the Fascist Squads; and 'from above', by the active support the Fascists received from the landlords and the state. Supported by organized landlords and blessed with the authorities' benevolence, the Squads were able to destroy - physically and politically - the legitimately constituted provincial governments of the Socialists. The alliance with the landlords determined the Squads' almost exclusive attacks on Socialist provincial strongholds that constituted the greatest threat to the landlords' interests, while provinces dominated by the ruling Liberal party were excluded from the Squads' path of 'punitive expeditions'.

Assessment of the 18-month permanence of onlay tip cartilage grafts following rhinoplasty.

PubMed

Persichetti, Paolo; Simone, Pierfranco; Carusi, Carlo

2013-09-01

Augmentation rhinoplasty requires addition of materials of various natures to reshape the nasal pyramid. Onlay tip grafts are single or multilayered grafts placed horizontally over the alar domes. The aim of the present study was to assess the 18-month permanence of onlay septal cartilage grafts. Twenty-eight patients underwent rhinoplasty with onlay tip cartilage graft, between June 2008 and November 2008 at the Campus Bio-Medico University in Rome, Italy. They were reviewed and photographed 6 months and 18 months postoperatively. Comparison of 6-month and 18-month postoperative pictures was performed with Adobe Photoshop CS. Measurements on pictures were taken with AutoCAD. Comparison of photographs showed no visible difference in nasal tip projection. Comparison of the measurements of tip projection showed a mean reduction of 0.06 mm (0.19%). Considerable stability of nasal tip projection after rhinoplasty with onlay tip grafts was observed postoperatively. Comparison of standardised digital photographs is a valid procedure to assess contour alterations of various anatomical structures after plastic surgery.

Drug prescribing during pregnancy in a central region of Italy, 2008-2012.

PubMed

Ventura, Martina; Maraschini, Alice; D'Aloja, Paola; Kirchmayer, Ursula; Lega, Ilaria; Davoli, Marina; Donati, Serena

2018-05-15

Drug consumption during pregnancy is a matter of concern, especially regarding drugs known or suspected to be teratogens. Little is known about drug use in pregnant women in Italy. The present study is aimed at examining the prevalence, and to detect potential inappropriateness of drug prescribing among pregnant women in Latium, a region of central Italy. This retrospective study was conducted on a cohort of women aged 18-45 years who delivered between 2008 and 2012 in public hospitals. Women were enrolled through the Regional Birth Register. After linking the regional Health Information Systems and the Regional Drug Claims Register, women's clinical data and prescribed medications were analyzed. Italian Medicine Agency (AIFA) and US Food and Drug Administration (FDA) evidence were used to investigate inappropriate prescribing and teratogenic risk. Excluding vitamins and minerals, 80.6% (n = 153,079) of the women were prescribed at least one drug during pregnancy, with an average of 4.6 medications per pregnancy. Drugs for blood and hematopoietic organs were the most commonly prescribed (53.0%,), followed by anti-infectives for systemic use (50.7%). Among the inappropriate prescriptions, progestogen supplementation was given in 20.1% of pregnancies; teratogen drugs were prescribed in 0.8%, mostly angiotensin co-enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) (0.3%). In Latium, drugs are widely used in pregnancy. Prescriptions of inappropriate drugs are observed in more than a fifth of pregnancies, and teratogens are still used, despite their known risk. Continuous updates of information provided to practitioners and an increased availability of information to women might reduce inappropriate prescribing.

Situation Reports--Guadeloupe, Italy, Nigeria, and Norway.

ERIC Educational Resources Information Center

International Planned Parenthood Federation, London (England).

Data relating to population and family planning are presented in these situation reports for four foreign countries: Guadeloupe, Italy, Nigeria, and Norway. Information is provided, where appropriate and available, under two topics, general background and family planning situation. General background covers ethnic groups, language, religion,…

Congenital syphilis in Italy: a multicentre study.

PubMed

Tridapalli, Elisabetta; Capretti, Maria Grazia; Reggiani, Maria Letizia Bacchi; Stronati, Mauro; Faldella, Giacomo

2012-05-01

To study the prevalence of congenital syphilis and its risk factors in Italy. Prospective study from 1 July 2006 to 30 June 2007. Data on mother-child pairs were collected for every syphilis seropositive mother. Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100,000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.

Environmental quality and sustainability in the province of Reggio Emilia (Italy): using multi-criteria analysis to assess and compare municipal performance.

PubMed

Ferrarini, A; Bodini, A; Becchi, M

2001-10-01

Sustainability has become an increasingly significant issue, although practical implementation remains difficult. In Italy, promoting sustainability is particularly problematic at the provincial and municipal level, where the lack of resources and expertise, and the effects of uncoordinated policies make it difficult to achieve minimum requirements to make sustainable policies operational. One essential requirement is knowledge of baseline environmental conditions in each municipality. In the province of Reggio Emilia (Northern Italy) Legambiente, an environmental association, launched an initiative called 'Ecopaese' aimed at gathering data on environmental conditions and stimulating local administrations to implement sustainable policies. To this end, the state of the environment in the 45 municipalities within the province has been monitored using 25 indicators. Their values have been used to rank the municipalities by multiple criteria analysis (MCA). The results of this comparative approach provide information about the level of sustainability attained in the province as a whole as well as in the single municipalities. It is hoped that it will provide the basis for direct action plans at the provincial level by identifying areas for remedial action, as recommended by Agenda 21, the declaration adopted by many countries attending the Rio Summit in 1992.

Fotometria superficial BVRI de 18 galáxias fracas

NASA Astrophysics Data System (ADS)

Saraiva, M. F. O.; Silva, P. R.

2003-08-01

Conhecer as propriedades de galáxias a diferentes redshifts é uma questão fundamental para entender o problema da formação e evolução das galáxias, e desde a década passada tem se intensificado fortemente o estudo de galáxias muito distantes. No entanto parece haver um interesse menor em galáxias a distâncias intermediárias, que aparecem como objetos de fundo em imagens de objetos próximos, e que são igualmente importantes. Examinando imagens BVRI de longa exposição, ótimo sinal/ruído, grande campo (46'x46'), das vizinhanças de NGC 7479, detectamos 18 galáxias fracas (18 < B < 21) nessas imagens. Neste trabalho, apresentamos a fotometria superficial desses objetos. Determinamos coordenadas equatoriais, magnitudes e cores integradas, perfis de brilho e de cor, e parâmetros isofotais calculados por ajuste de ellipses, dentro do limite permitido pela baixa resolução espacial dos dados (1,35 segarc/pixel). Nosso objetivo é procurar correlações entre as propriedades das galáxias e, tentativamente, comparar esses dados com aqueles de galáxias de redshift conhecido, disponíveis na literatura, para estimar suas distâncias (a partir da relação cor x redshift) e suas morfologias. Uma análise preliminar nesse sentido mostrou que as cores aparentes B-V, V-R e V-I dos objetos da nossa amostra, a menos de duas exceções, ocupam regiões bem definidas nos diagramas cor-cor, e não apresentam diferenças notáveis em relação às cores típicas de galáxias próximas.

76 FR 65179 - Certain Pasta From Italy: Extension of Time Limit for the Final Results of the Countervailing...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

... DEPARTMENT OF COMMERCE International Trade Administration [C-475-819] Certain Pasta From Italy... administrative review of the countervailing duty order on certain pasta from Italy, covering the period January 1, 2009, through December 31, 2009. See Certain Pasta from Italy: Preliminary Results of the 14th (2009...

75 FR 37386 - Certain Pasta from Italy: Final Results of the 13th (2008) Countervailing Duty Administrative Review

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-29

... DEPARTMENT OF COMMERCE International Trade Administration [C-475-819] Certain Pasta from Italy... pasta from Italy for the period January 1, 2008, through December 31, 2008. On April 13, 2010, we published the Preliminary Results of this review. See Certain Pasta From Italy: Preliminary Results of the...

76 FR 22725 - Cut-to-Length Carbon Steel Plate From India, Indonesia, Italy, Japan, and Korea; Scheduling of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-22

... Review)] Cut-to-Length Carbon Steel Plate From India, Indonesia, Italy, Japan, and Korea; Scheduling of...-Length Carbon Steel Plate From India, Indonesia, Italy, Japan, and Korea AGENCY: United States... from India, Indonesia, Italy, and Korea and/or therevocation of the antidumping duty orders on cut-to...

The relationship between happiness and health: evidence from Italy.

PubMed

Sabatini, Fabio

2014-08-01

We test the relationship between happiness and self-rated health in Italy. The analysis relies on a unique dataset collected through the administration of a questionnaire to a representative sample (n = 817) of the population of the Italian Province of Trento in March 2011. Based on probit regressions and instrumental variables estimates, we find that happiness is strongly correlated with perceived good health, after controlling for a number of relevant socio-economic phenomena. Health inequalities based on income, work status and education are relatively contained with respect to the rest of Italy. As expected, this scales down the role of social relationships. Copyright © 2014 Elsevier Ltd. All rights reserved.

Impact of a DRG-based hospital financing system on quality and outcomes of care in Italy.

PubMed Central

Louis, D Z; Yuen, E J; Braga, M; Cicchetti, A; Rabinowitz, C; Laine, C; Gonnella, J S

1999-01-01

OBJECTIVE: To examine potential changes in quality of care associated with a recent financing system implementation in Italy: in 1995, hospital financing reform implemented in Italy included the introduction of a DRG-based hospital financing system with the goals of controlling the growth of hospital costs and making hospitals more accountable for their productivity. DATA SOURCES: Hospital discharge abstract data from 1993 through 1996 for all hospitals (N=32) in the Friuli-Venezia-Giulia region of Italy. Regional population data were used to calculate rates. STUDY DESIGN: Changes between 1993 and 1996 in hospital admissions, length of stay, mortality rates, severity of illness, and readmission rates were studied for nine common medical and surgical conditions: appendicitis, diabetes mellitus, colorectal cancer, cholecystitis, bronchitis/chronic obstructive pulmonary disease (COPD), bacterial pneumonia, coronary artery disease, cerebrovascular disease, and hip fracture. PRINCIPAL FINDINGS: The total number of ordinary hospital admissions decreased from 244,581 to 204,054 between 1993 and 1996, a population-based decrease of 17.3 percent (p<.001). The mean length of stay decreased from 9.1 days to 8.8 days, resulting in a 21.1 percent decrease in hospital bed days (p<.001). Day hospital use increased sevenfold from 16,871 encounters in 1993 to 108,517 encounters in 1996. The largest decrease in hospital admissions among study conditions was a 41 percent decrease for diabetes (from 2.25 per 1,000 in 1993 to 1.31 in 1996, p<.001). For eight of the nine conditions, severity of illness increased. Differences between severity-adjusted expected and observed in-hospital mortality rates were small. CONCLUSIONS: Observed trends showed a decrease in ordinary hospital admissions, an increase in day hospital admissions, and a greater severity of illness among hospitalized patients. There was little or no change in mortality and readmission rates. Administrative data can be used

First Rescue Under the Rubble: The Medical Aid in the First Hours After the Earthquake in Amatrice (Italy) on August 24, 2016.

PubMed

Blasetti, Angelo Geremia; Petrucci, Emiliano; Cofini, Vincenza; Pizzi, Barbara; Scimia, Paolo; Pozone, Tullio; Necozione, Stefano; Fusco, Pierfrancesco; Marinangeli, Franco

2018-02-01

Specific Event Identifiers a. Event Type: Earthquake measuring 6.2 (SD=0.016) on the moment magnitude; b. Event Onset: August 24, 2016 - 03:36:32 CEST (01:36 UTC); c. Location of Event: Central Italy, in the town of Amatrice; d. Geographic Coordinates: latitude (DMS): 42°37'45.77″N; longitude (DMS): 13°17'18.14″E; elevation: 955 meters above sea-level; e. Dates: August 24, 2016 at 4:48 AM; f. Response Type: Medical Relief. On August 24, 2016, an earthquake hit the town of Amatrice (Italy). This study aims to document the first medical aid provided to earthquake victims in Amatrice immediately following the earthquake. Patient data were collected and recorded during the first clinical evaluation and before definitive hospitalization. Blood gas tests were performed on survivors extricated from the rubble using the iSTAT (Abbott Point of Care Inc.; Princeton, New Jersey USA) handheld blood analyzer. Performing "victim-side" blood gas tests could provide concrete information to facilitate clinical evaluation and decision making when treating buried victims. After a natural disaster, it is essential to provide effective analgo-sedation to victims. Blasetti AG , Petrucci E , Cofini V , Pizzi B , Scimia P , Pozone T , Necozione S , Fusco P , Marinangeli F . First rescue under the rubble: the medical aid in the first hours after the earthquake in Amatrice (Italy) on August 24, 2016. Prehosp Disaster Med. 2018;33(1):109-113.

A Comparison of Inpatient Adult Psychiatric Services in Italy and Canada.

PubMed

Guaiana, Giuseppe; O'Reilly, Richard; Grassi, Luigi

2018-05-03

We examine the possibility the Organisation for Economic Co-operation and Development (OECD) bed count for Italy may be an underestimation of the actual beds available. We compared bedded services for mental disorders in two regions in Italy and Canada respectively. We found out that if we consider acute psychiatric beds only, the district of Ferrara has 30 beds (8.5 per 100,000) and the Middlesex and Elgin Counties have 89 beds (16.3 beds for 100,000). However, if we include the rehabilitation beds (that are located within a hospital setting in Ontario and in a residential community setting in Ferrara), we find that the district of Ferrara has 95 beds (27.0 per 100,000) and the Middlesex and Elgin Counties have 176 beds (32.3 per 100,000). As a result, the 10/100,000 beds rate for Italy reported by the OECD is an underestimate compared to figures reported for most other countries, as the beds included are hospital beds only.

75 FR 81309 - Stainless Steel Plate from Belgium, Italy, Korea, South Africa, and Taiwan

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-27

... (Second Review)] Stainless Steel Plate from Belgium, Italy, Korea, South Africa, and Taiwan AGENCY: United... countervailing duty orders on stainless steel plate from Belgium and South Africa and the antidumping duty orders on stainless steel plate from Belgium, Italy, Korea, South Africa, and Taiwan. SUMMARY: The...

OECD Skills Strategy Diagnostic Report: Italy 2017

ERIC Educational Resources Information Center

OECD Publishing, 2017

2017-01-01

Skills demands are increasing and changing rapidly everywhere, as advanced economies adapt to globalisation, technological change and ageing. Yet Italy is struggling more than other advanced economies to make the transition towards a thriving and dynamic skills-based society. The Organisation for Economic Cooperation and Development (OECD) Skills…

Actors in Corruption: Business Politicians in Italy.

ERIC Educational Resources Information Center

della Porta, Donatella

1996-01-01

Argues that the development of political corruption brings about important changes in the political system and in the characteristics of the political class. Describes the emergence and activities of a group of "business politicians" in Italy who have transformed political parties into socializing agencies for illicit activities. (MJP)

Italy INAF Analysis Center Report

NASA Technical Reports Server (NTRS)

Negusini, M.; Sarti, P.

2013-01-01

This report summarizes the activity of the Italian INAF VLBI Analysis Center. Our Analysis Center is located in Bologna, Italy and belongs to the Institute of Radioastronomy, which is part of the National Institute of Astrophysics. IRA runs the observatories of Medicina and Noto, where two 32-m VLBI AZ-EL telescopes are situated. This report contains the AC's VLBI data analysis activities and shortly outlines the investigations into the co-locations of space geodetic instruments.

78 FR 9364 - Certain Pasta From Italy: Notice of Final Results of 15th Antidumping Duty Administrative Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-08

... DEPARTMENT OF COMMERCE International Trade Administration [A-475-818] Certain Pasta From Italy... administrative review of the antidumping duty order on certain pasta from Italy. The period of review (POR) is... administrative review of the antidumping duty order on certain pasta from Italy.\\2\\ On October 26, 2012, Rummo...

76 FR 48122 - Certain Pasta From Italy: Notice of Court Decision Not in Harmony With Final Results of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-08

... DEPARTMENT OF COMMERCE International Trade Administration [A-475-818] Certain Pasta From Italy... antidumping duty order on certain pasta from Italy covering the period of review (``POR'') of July 1, 2005... Department published its final results of the administrative review for pasta from Italy for the period from...

76 FR 12702 - Certain Cut-to-Length Carbon-Quality Steel Plate From India, Indonesia, Italy, and the Republic...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-08

...-837] Certain Cut-to-Length Carbon-Quality Steel Plate From India, Indonesia, Italy, and the Republic...-to-length carbon-quality steel plate from India, Indonesia, Italy, and the Republic of Korea (``Korea...-length carbon-quality steel plate from India, Indonesia, Italy, and Korea pursuant to section 751(c) of...

18. Photocopy of Architectural Layout drawing, dated 25 June, 1993 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Photocopy of Architectural Layout drawing, dated 25 June, 1993 by US Air Force Space Command. Original drawing property of United States Air Force, 21' Space Command AL-2 PAVE PAWS SUPPORT SYSTEMS - CAPE COD AFB, MASSACHUSETTS - SITE PLAN. DRAWING NO. AL-2 - SHEET 3 OF 21. - Cape Cod Air Station, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

[Monitoring microbiological safety of small systems of water distribution. Comparison of two sampling programs in a town in central Italy].

PubMed

Papini, Paolo; Faustini, Annunziata; Manganello, Rosa; Borzacchi, Giancarlo; Spera, Domenico; Perucci, Carlo A

2005-01-01

To determine the frequency of sampling in small water distribution systems (<5,000 inhabitants) and compare the results according to different hypotheses in bacteria distribution. We carried out two sampling programs to monitor the water distribution system in a town in Central Italy between July and September 1992; the Poisson distribution assumption implied 4 water samples, the assumption of negative binomial distribution implied 21 samples. Coliform organisms were used as indicators of water safety. The network consisted of two pipe rings and two wells fed by the same water source. The number of summer customers varied considerably from 3,000 to 20,000. The mean density was 2.33 coliforms/100 ml (sd= 5.29) for 21 samples and 3 coliforms/100 ml (sd= 6) for four samples. However the hypothesis of homogeneity was rejected (p-value <0.001) and the probability of II type error with the assumption of heterogeneity was higher with 4 samples (beta= 0.24) than with 21 (beta= 0.05). For this small network, determining the samples' size according to heterogeneity hypothesis strengthens the statement that water is drinkable compared with homogeneity assumption.

Using the Depression Anxiety Stress Scale 21 (DASS-21) across cultures.

PubMed

Oei, Tian P S; Sawang, Sukanlaya; Goh, Yong Wah; Mukhtar, Firdaus

2013-01-01

The DASS-21 is a well-established instrument for measuring depression, anxiety, and stress with good reliability and validity reported from Hispanic American, British, and Australian adults. However, the lack of appropriate validation among Asian populations continues to pose concerns over the use of DASS-21 in Asian samples. Cultural variation may influence the individual's experience and emotional expression. Thus, when researchers and practitioners employ Western-based assessments with Asian populations by directly translating them without an appropriate validation, the process can be challenging. We conducted a series of rigorous statistical tests and minimized any potential confounds from the demographic information. Following factor analyses, we performed multigroup analysis across six nations to demonstrate consistency of our findings. The advantages of this revised DASS-18 stress scale are twofold. First, it possesses fewer items, which results in a cleaner factorial structure. Second, it has a smaller interfactor correlation. With these justifications, the revised DASS-18 stress scale is potentially more suitable for Asian populations. Nonetheless, given limitations, findings should be considered preliminary.

77 FR 48964 - Certain Pasta From Italy: Notice of Court Decision Not in Harmony With Final Results of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-15

... DEPARTMENT OF COMMERCE International Trade Administration [A-475-818] Certain Pasta From Italy... pasta from Italy with respect to the margin assigned to Atar S.r.L. (Atar) covering the period of review... Review of the Antidumping Duty Order on Certain Pasta from Italy, 72 FR 7011 (February 14, 2007) (Final...

75 FR 59744 - Stainless Steel Plate From Belgium, Italy, Korea, South Africa, and Taiwan

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-28

... (Second Review)] Stainless Steel Plate From Belgium, Italy, Korea, South Africa, and Taiwan AGENCY: United... Africa and the antidumping duty orders on stainless steel plate from Belgium, Italy, Korea, South Africa... revocation of the countervailing duty orders on stainless steel plate from Belgium and South Africa and the...

Egg-related Salmonella enteritidis, Italy, 1991

PubMed Central

Binkin, N.; Scuderi, G.; Novaco, F.; Giovanardi, G. L.; Paganelli, G.; Ferrari, G.; Cappelli, O.; Ravaglia, L.; Zilioli, F.; Amadei, V.; Magliani, W.; Viani, I.; Riccò, D.; Borrini, B.; Magri, M.; Alessandrini, A.; Bursi, G.; Barigazzi, G.; Fantasia, M.; Filetici, E.; Salmaso, S.

1993-01-01

In recent years, Salmonella enteritidis has become an increasingly important public health problem in Italy. In some parts of the country, the fraction of total human salmonella isolates accounted for by S. enteritidis has risen from 3-4% in the mid-1980s to more than 30% in 1990. Between 1990 and 1991, the number of reported S. enteritidis outbreaks increased more than sixfold. The 33 outbreaks reported in 1991 occurred in seven contiguous regions in northern and central Italy and were clustered in time between June and October; in the majority, products containing raw or undercooked shell eggs were implicated. Five of the egg-related outbreaks that occurred within a 30 kilometre radius over a 7-week period were investigated in detail. A phage type 1 strain containing a 38·9 MDa plasmid appeared responsible for three of the outbreaks, while in the remaining two a phage type 4 strain, also with a 38·9 MDa plasmid was isolated. Efforts are being made to enhance epidemiological surveillance and laboratory evaluation, and the use of pasteurized eggs has been recommended for high-risk populations. PMID:8472765

Multiple Nonconformities in Ice-Walled Lake Successions Indicate Periods with Cold Summers (24.4 - 22.5 ka, 21.1 - 19.2 ka, 18.5 - 18.1 ka) during the Last Deglaciation in Northeastern Illinois, USA

NASA Astrophysics Data System (ADS)

Curry, B. B.

2014-12-01

Unprecedented age control on many last glacial stratigraphic units and morainal ice-margin positions are interpreted from AMS radiocarbon ages of tundra plant macrofossils archived in low-relief ice-walled lake plain (IWLP) deposits the Lake Michigan Lobe (south-central Laurentide Ice Sheet). IWLPs are periglacial features that formed on morainal dead-ice permafrost. Lacustrine sediment, and the fossils contained therein, had physical and temporal proximity to the glacier which formed the underlying moraine. In modern ice-walled lakes, as the lake's ice cover begins to melt, moats form which allows access of sloughing tundra-mantled active layer sediment (soil) into the lakes. Multiple AMS ages from two sites with proglacial sediment buried by glacial max LIS diamicton, and IWLPs reveal evidence of episodic plant growth and sedimentation including ca. 24.0 to 24.4 ka (post Shelby Phase), 22.5 to 21.1 ka (post Livingston Phase), 18.1 to 17.4 ka (post Woodstock Phase). Although presently based on negative evidence, the associated nonconformities (listed in title) indicate periods when cold conditions did not promote development of the estival moat. Although the evidence does not preclude tundra growth during the cold summers, there was little landscape modification due to limited thawing of the active layer. At approximately the onset of the 19.2-18.5 "warm" period, at least two large deglacial discharge events flooded the Fox and Kankakee tributary valleys of the Illinois River. The latter, known as the Kankakee Torrent, occurred at 19.05 - 18.85 ka (σ1 range) at the Oswego channel complex. The temporal coincidence of the torrents and sedimentation in ice-walled lakes suggests that the post-Livingston Phase nonconformity (21.1 - 19.2 ka) was a period of lessened meltwater discharge through subglacial conduits (tunnel valleys) as the frozen toe promoted formation of subglacial lakes, buildup of pore-water pressures, and the release of subglacial water as "torrents

Trace elements in raw milk of buffaloes (Bubalus bubalis) from Campania, Italy.

PubMed

Esposito, Mauro; Miedico, Oto; Cavallo, Stefania; Pellicanò, Roberta; Rosato, Guido; Baldi, Loredana; Chiaravalle, A Eugenio

2017-10-15

The profile of 18 trace elements was traced in 68 milk samples collected from buffalo farms in the territory known as the "Land of Fires" in the Campania region (Italy). This area has been polluted by the illegal dumping in fields of industrial or domestic waste, wich is sometimes then burned spreading toxic contaminants. Milk from buffaloes raised on rural farms might be a good indicator of environmental contamination risk in the human food chain. Trace element analysis in milk was performed using mass spectrometry. One milk sample was found to be non-compliant due to high Pb concentration. In the absence of threshold values for the elements, established through legislation, the results were compared with similar studies from other countries, and in most cases the content determined in this study was in agreement with values reported elsewhere and do not represent a risk to human health. Copyright © 2017 Elsevier Ltd. All rights reserved.

Hospitalisation among immigrants in Italy

PubMed Central

Cacciani, Laura; Baglio, Giovanni; Rossi, Lorenza; Materia, Enrico; Marceca, Maurizio; Geraci, Salvatore; Spinelli, Angela; Osborn, John; Guasticchi, Gabriella

2006-01-01

Background Immigration is increasing in Italy. In 2003, 2.6 million foreign citizens lived in the country; 52% were men and the majority were young adults who migrated for work. The purpose of this study was to investigate differences in hospitalisation between immigrants and the resident population during the year 2000 in the Lazio region. Methods Hospital admissions of immigrants from Less Developed Countries were compared to those of residents. We measured differences in hospitalisation rates and proportions admitted. Results Adult immigrants have lower hospitalisation rates than residents (134.6 vs. 160.5 per thousand population for acute care; 26.4 vs. 38.3 for day care). However, hospitalisation rates for some specific causes (injuries, particularly for men, infectious diseases, deliveries and induced abortions, ill-defined conditions) were higher for immigrants than for residents. Immigrants under 18 years seem to be generally healthy; causes of admission in this group are similar to those of residents of the same age (respiratory diseases, injuries and poisoning). The only important differences are for infectious and parasitic diseases, with a higher proportion among immigrant youths. Conclusion The low hospitalisation rates for foreigners may suggest that they are a population with good health status. However, critical areas, related to poor living and working conditions and to social vulnerability, have been identified. Under-utilisation of services and low day care rates may be partially due to administrative, linguistic, and cultural barriers. As the presence of foreigners becomes an established phenomenon, it is important to evaluate their epidemiological profile, develop instruments to monitor and fulfil their specific health needs and plan health services for a multi-ethnic population. PMID:16689988

40 CFR 86.007-21 - Application for certification.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Application for certification. 86.007-21 Section 86.007-21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... recirculation, the manufacturer must provide a detailed description of the control system the engine will use to...

Earthquake Forecasting System in Italy

NASA Astrophysics Data System (ADS)

Falcone, G.; Marzocchi, W.; Murru, M.; Taroni, M.; Faenza, L.

2017-12-01

In Italy, after the 2009 L'Aquila earthquake, a procedure was developed for gathering and disseminating authoritative information about the time dependence of seismic hazard to help communities prepare for a potentially destructive earthquake. The most striking time dependency of the earthquake occurrence process is the time clustering, which is particularly pronounced in time windows of days and weeks. The Operational Earthquake Forecasting (OEF) system that is developed at the Seismic Hazard Center (Centro di Pericolosità Sismica, CPS) of the Istituto Nazionale di Geofisica e Vulcanologia (INGV) is the authoritative source of seismic hazard information for Italian Civil Protection. The philosophy of the system rests on a few basic concepts: transparency, reproducibility, and testability. In particular, the transparent, reproducible, and testable earthquake forecasting system developed at CPS is based on ensemble modeling and on a rigorous testing phase. Such phase is carried out according to the guidance proposed by the Collaboratory for the Study of Earthquake Predictability (CSEP, international infrastructure aimed at evaluating quantitatively earthquake prediction and forecast models through purely prospective and reproducible experiments). In the OEF system, the two most popular short-term models were used: the Epidemic-Type Aftershock Sequences (ETAS) and the Short-Term Earthquake Probabilities (STEP). Here, we report the results from OEF's 24hour earthquake forecasting during the main phases of the 2016-2017 sequence occurred in Central Apennines (Italy).

STS map of genes and anonymous DNA fragments on human chromosome 18 using a panel of somatic cell hybrids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Overhauser, J.; Mewar, R.; Rojas, K.

1993-02-01

Somatic cell hybrids containing different deleted regions of chromosome 18 derived form patients with balanced translocations or terminal deletions were used to create a deletion mapping panel. Twenty-four sequence-tagged sites (STSs) for 17 genes and 7 anonymous polymorphic DNA fragments were identified. These STSs were used to map the 24 loci to 18 defined regions of chromosome 18. Both ERV1, previously mapped to 18q22-q23, and YES1, previously mapped to 18q21.3, were found to map to 18p11.21-pter. Several genes previously mapped to 18q21 were found to be in the order cen-SSAV1-DCC-FECH-GRP-BCL2-PLANH2-tel. The precise mapping of genes to chromosome 18 should helpmore » in determining whether these genes may be involved in the etiology of specific chromosomal syndromes associated with chromosome 18. The mapping of the poloymorphic loci will assist in the integration of the physical map with the recombination map of chromosome 18. 43 refs., 2 figs., 1 tab.« less

Governance and Leadership in Public Schools: Opportunities and Challenges Facing School Leaders in Italy

ERIC Educational Resources Information Center

Paletta, Angelo; Bezzina, Christopher

2016-01-01

This article aims to explore the evolution of school leadership in Italy toward a model of leadership for learning. Italy is undergoing radical changes in the governance structures (school autonomy and accountability) affecting schools in general, and school principals in particular, based on the way they promote, manage, and monitor the…

137Cs activity concentration in mosses in the Calabria region, south of Italy

NASA Astrophysics Data System (ADS)

Caridi, F.; Belvedere, A.; D'Agostino, M.; Marguccio, S.

2017-05-01

Many studies carried out after the Chernobyl nuclear accident in 1986 showed that mosses are suitable bioindicators of the radioactive fall-out, given their long life expectancy. 137Cs activity concentration was measured through HPGe gamma spectrometry in different mosses (Hypnum Cupressiforme, Hypnum Andoi, Homalothecium Sericeum, Philonotis Fontana), collected, in 2008 and 2015, from four sampling sites in the Calabria region, south of Italy. Experimental specific activities allowed us to determine the effective and the biological half-time of 137Cs for the investigated plants. The effective half-time was found in the range from (4.2 ± 1.1) to (7.4 ± 1.8) years; the biological half-time varied from (4.9 ± 1.3) to (9.9 ± 2.4) years. Data reported in this article provide useful information on the environmental risk of the studied area and can be further used for a radiological mapping.

Epidemiological study of myasthenia gravis in the province of Reggio Emilia, Italy.

PubMed

Guidetti, D; Sabadini, R; Bondavalli, M; Cavalletti, S; Lodesani, M; Mantegazza, R; Cosi, V; Solime, F

1998-06-01

We carried out a retrospective incidence, prevalence and mortality survey of myasthenia gravis in the province of Reggio Emilia in Northern Italy. Based on 49 patients, the mean incidence per year for the period 1980 through 1994 was 7.8 per 1,000,000. On 31 December 1994 the prevalence rate was 117.5 per 1,000,000 for all patients, either active or recovered (50 cases in a population of 427,493) and 103.4 per 1,000,000 for the active disease. In the 15-year period 1980-1994 the average mortality rate was 1.0 per 1,000,000 per year. The average age at onset was 44.6 +/- 21.0, and the average age at the time of prevalence determination was 51.1 +/- 19.6 for the active disease. At the time of diagnosis, 21 patients (36.8%) were classed in group I according to Osserman's criteria, 31 in group II (54.4%), (19 in group II-A and 12 in group II-B), and the other 5 (8.8%) in group III. Of all the prevalence cases, 6 (12%) were in remission without therapy and 6 with therapy, while most of the others 16 (32%) were classed in group I, 15 (30%) in group II, and 1 (2%) in group III. Thymectomy was performed in 20 patients (35.1%), 12 (21%) had thymoma (malignant in 4 cases), 6 had thymic hyperplasia while in two patients thymic histology was normal. The relation the grade of Osserman's scale at the time of incidence and the presence of thymoma were significant. Higher grades of Osserman's scale were associated were malignant thymoma. Furthermore the relationship between thymectomy and the grade of Osserman's scale at the date of prevalence was significant for the presence of lower grades of Osserman's scale in the patients submitted to thymectomy.

Prevalence of Paget's disease of bone in Italy.

PubMed

Gennari, Luigi; Di Stefano, Marco; Merlotti, Daniela; Giordano, Nicola; Martini, Giuseppe; Tamone, Cristina; Zatteri, Roberto; De Lucchi, Roberto; Baldi, Carlo; Vattimo, Angelo; Capoccia, Silvia; Burroni, Luca; Geraci, Simone; De Paola, Vincenzo; Calabrò, Anna; Avanzati, Annalisa; Isaia, Giancarlo; Nuti, Ranuccio

2005-10-01

We examined the prevalence of PDB in Italy from radiological, scintigraphic, and biochemical surveys in two Italian towns. Prevalence rates varied from 0.7% to 2.4%, were higher in males than in females, and slightly differed between the two towns. Unlike previous studies in populations of British descent, no secular trend for a decreasing prevalence emerged. Clinical, radiological, and necropsy data from different countries suggested pronounced geographical variations in the prevalence of Paget's disease of bone (PDB). Despite the impact of the disease on the population, there are limited data on the prevalence of PDB in Italy. The objective of this study was to estimate the prevalence of PDB in the district of Siena (Central Italy) and Turin (Northern Italy) from radiological, biochemical, and scintigraphic surveys. We examined a sample of 1778 consecutive pelvic radiographs performed between 1999 and 2000 at the Hospital Radiology Unit in Siena and 6609 pelvic radiographs performed in 1986-1987, 1992-1993, and 1999-2002 from the Radiology Department of Molinette Hospital in Turin. In Siena, 7906 consecutive (99m)TC-MDP bone scans performed over a 4-year period (January 2000 to May 2004) were also screened for the presence of PDB, and the prevalence of elevated alkaline phosphatase (ALP) levels (>300 UI/liter) was estimated from 7449 computerized medical records over a 3-year period (January 2000 to February 2003). The finding of PDB on the pelvic radiograph and bone scan was based on standardized radiological criteria. At the end of the radiological surveys, 16/1778 pelvic PDB cases (8 males and 8 females) were observed in Siena and 41/6609 (27 males and 14 females) in Turin. The crude prevalence of the disease was 0.89% in Siena and 0.62% in Turin. Given that pelvic involvement is commonly described in 60-90% of PDB patients, the estimated overall prevalence of PDB ranged from 1.0% to 1.5% in Siena and from 0.7% to 1.0% in Turin. No decrease in the prevalence

Arithmetic Education and Learning Disabilities in Italy

ERIC Educational Resources Information Center

Cornoldi, C.; Lucangeli, D.

2004-01-01

In the first part of this article, we briefly present the context of mathematics education in Italy and its specific programs, teaching and assessment methods, use of psychological concepts, and policies in favor of pupils with difficulties. We illustrate the importance and the role of mathematics teachers' associations. In the second part, we…

[A method for identifying people with a high level of frailty by using a population database, Varese, Italy].

PubMed

Pisani, Salvatore; Gambino, Maria; Balconi, Lorena; Degli Stefani, Cristina; Speziali, Sabina; Bonarrigo, Domenico

2016-01-01

Since over 10 years, the Lombardy Region (Italy) has developed a system for classifying all persons registered with the healthcare system (database of persons registered with a general practitioner), according to their use of major healthcare services (hospitalizations, outpatient consultations, pharmaceutical) and whether they are exempt from copayment fees for disease-specific medications and healthcare services. The present study was conducted by the local health authorities of the province of Varese (Lombardy region, Italy) with 894.039 persons registered in the database of whom 258.770 (28.9%) with at least one chronic condition, 104.731 (11.7%) with multiple chronic conditions and 195.296 (21.8%) elderly persons. The aim was to evaluate death rates in different subgroups of patients entered in the database, including persons with chronic diseases and elderly persons. Standardized mortality rates were calculated for the year 2012. Compared with the general population, relative risk for mortality was 4,1 (95% confidence Intervals 4,0-4,2) in the elderly and 1,3 (95% confidence intervals 1,3-1,4) in chronic patients. This confirms that elderly persons have a higher level of frailty with respect to patients with chronic conditions. Mortality was found to be 28 times higher in elderly persons over 74 years of age, affected by high cost conditions such as cancer and cardiac disease, with respect to the general population.

Summary of the Second International Planetary Dunes Workshop: Planetary Analogs - Integrating Models, Remote Sensing, and Field Data, Alamosa, Colorado, USA, May 18-21, 2010

USGS Publications Warehouse

Fenton, L.K.; Bishop, M.A.; Bourke, M.C.; Bristow, C.S.; Hayward, R.K.; Horgan, B.H.; Lancaster, N.; Michaels, T.I.; Tirsch, D.; Titus, T.N.; Valdez, A.

2010-01-01

The Second International Planetary Dunes Workshop took place in Alamosa, Colorado, USA from May 18-21, 2010. The workshop brought together researchers from diverse backgrounds to foster discussion and collaboration regarding terrestrial and extra-terrestrial dunes and dune systems. Two and a half days were spent on five oral sessions and one poster session, a full-day field trip to Great Sand Dunes National Park, with a great deal of time purposefully left open for discussion. On the last day of the workshop, participants assembled a list of thirteen priorities for future research on planetary dune systems. ?? 2010.

Modelling the resource implications of managing adults with Fabry disease in Italy.

PubMed

Guest, Julian F; Concolino, Daniela; Di Vito, Raffaele; Feliciani, Claudio; Parini, Rossella; Zampetti, Anna

2011-07-01

This study estimated the resource implications and budget impact of managing adults with Fabry disease in Italy, from the perspective of the Servizio Sanitario Nazionale (SSN). A decision model was constructed using published clinical outcomes and clinician-derived resource utilisation estimates depicting the management of adults with Fabry disease in Italy. The expected annual cost of managing 220 existing and 20 new Fabry patients in Italy was estimated to be €28·3 million. In an average year, patients receiving enzyme replacement therapy (ERT) with 0·2 mg kg(-1) agalsidase alfa (Replagal; Shire Human Genetic Therapies, Basingstoke, Hampshire, UK) or 1·0 mg kg(-1) agalsidase beta (Fabrazyme; Genzyme Europe BV, Naarden, The Netherlands) are collectively expected to make 4500 hospital attendances to a day ward for infusions, which equates to 2000 eight-h days on the day ward associated with ERT. If all ERT-treated patients received their infusions at home, there would be a marginal reduction in the annual health care cost to manage these patients, and the total annual number of days on the day ward associated with ERT in the second year could potentially be reduced from a mean 2000 to zero, thereby releasing substantial hospital resources for use by non-Fabry patients. Currently, only agalsidase alfa is licensed for home treatment in Italy; hence, only patients receiving this enzyme could be offered home treatment. Use of agalsidase alfa (0·2 mg kg(-1) ) instead of agalsidase beta (1·0 mg kg(-1)) has the potential to reduce health care costs and release hospital resources in different specialities for alternative use by non-Fabry patients, thereby improving the efficiency of the public health care system in Italy. © 2011 The Authors. European Journal of Clinical Investigation © 2011 Stichting European Society for Clinical Investigation Journal Foundation.

Italian cancer figures--Report 2015: The burden of rare cancers in Italy.

PubMed

Busco, Susanna; Buzzoni, Carlotta; Mallone, Sandra; Trama, Annalisa; Castaing, Marine; Bella, Francesca; Amodio, Rosalba; Bizzoco, Sabrina; Cassetti, Tiziana; Cirilli, Claudia; Cusimano, Rosanna; De Angelis, Roberta; Fusco, Mario; Gatta, Gemma; Gennaro, Valerio; Giacomin, Adriano; Giorgi Rossi, Paolo; Mangone, Lucia; Mannino, Salvatore; Rossi, Silvia; Pierannunzio, Daniela; Tavilla, Andrea; Tognazzo, Sandro; Tumino, Rosario; Vicentini, Massimo; Vitale, Maria Francesca; Crocetti, Emanuele; Dal Maso, Luigino

2016-01-01

2008 in the AIRTUM database, and followed up to 31 December 2009, were calculated using complete cohort survival analysis. To estimate the observed prevalence in Italy, incidence and follow-up data from 11 CRs for the period 1992-2006 were used, with a prevalence index date of 1 January 2007. Observed prevalence in the general population was disentangled by time prior to the reference date (≤2 years, 2-5 years, ≤15 years). To calculate the complete prevalence proportion at 1 January 2007 in Italy, the 15-year observed prevalence was corrected by the completeness index, in order to account for those cancer survivors diagnosed before the cancer registry activity started. The completeness index by cancer and age was obtained by means of statistical regression models, using incidence and survival data available in the European RARECAREnet data. In total, 339,403 tumours were included in the incidence analysis. The annual incidence rate (IR) of all 198 rare cancers in the period 2000-2010 was 147 per 100,000 per year, corresponding to about 89,000 new diagnoses in Italy each year, accounting for 25% of all cancer. Five cancers, rare at European level, were not rare in Italy because their IR was higher than 6 per 100,000; these tumours were: diffuse large B-cell lymphoma and squamous cell carcinoma of larynx (whose IRs in Italy were 7 per 100,000), multiple myeloma (IR: 8 per 100,000), hepatocellular carcinoma (IR: 9 per 100,000) and carcinoma of thyroid gland (IR: 14 per 100,000). Among the remaining 193 rare cancers, more than two thirds (No. 139) had an annual IR <0.5 per 100,000, accounting for about 7,100 new cancers cases; for 25 cancer types, the IR ranged between 0.5 and 1 per 100,000, accounting for about 10,000 new diagnoses; while for 29 cancer types the IR was between 1 and 6 per 100,000, accounting for about 41,000 new cancer cases. Among all rare cancers diagnosed in Italy, 7% were rare haematological diseases (IR: 41 per 100,000), 18% were solid rare

Italy feels the effect of another deadly quake

NASA Astrophysics Data System (ADS)

Banks, Michael

2016-12-01

Using radar data from the Copernicus Sentinel-1 satellites, the European Space Agency has released images showing the devastating effect of the 6.5-magnitude earthquake that struck central Italy on 30 October - the largest in the country for over three decades.

77 FR 39735 - Stainless Steel Butt-Weld Pipe Fittings From Italy, Malaysia, and the Philippines

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-05

... revocation of the antidumping duty orders on stainless steel butt-weld pipe fittings From Italy, Malaysia... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 731-TA-865-867 (Second Review)] Stainless Steel Butt-Weld Pipe Fittings From Italy, Malaysia, and the Philippines Determination On the basis of the...

Organization and regional distribution of centers for the management of children and adolescents with diabetes in Italy.

PubMed

Giorgetti, Chiara; Ferrito, Lucia; Zallocco, Federica; Iannilli, Antonio; Cherubini, Valentino

2015-10-08

The incidence of type 1 diabetes in childhood is increasing by 3 % per year, placing growing demands on healthcare professionals and medical expenditures. Aim of this study wars to assess the organization of care to children with diabetes in Italy. During 2012 a structured questionnaire was sent to all of the members of Italian Society of Paediatric Endocrinology and Diabetology (ISPED). Questions examined organizational structure of Centers, personnel dedicated to the care of children with diabetes, number of subjects followed, local legal legislation supporting centres. A total of 68 centers taking care to 15,563 children and adolescents with diabetes under 18 years of age were identified with a prevalence of 1.4 per 1,000 people. A wide variation in the organizational background was also reported. Fourty-four centers were organized as outpatient departments, 17 as simple units, 5 as complex units and 2 as simple departmental structures. Most centers had a multidisciplinary team. Ten out of twenty Italian regions had introduced supportive regional legislation, but it was fully applied only in six of them. Great differences between regions were found in organizational structures, staffing levels and supportive legislation. The national legislation on diabetes was broadly implemented throughout the country regions. Further efforts are needed to improve standards and consistency of pediatric diabetes care in Italy.

The Evolution of Professional Nursing Culture in Italy

PubMed Central

Rocco, Gennaro; Affonso, Dyanne D.; Mayberry, Linda J.; Stievano, Alessandro; Alvaro, Rosaria; Sabatino, Laura

2014-01-01

We explored the perceptions of Italian nurses regarding their developing culture as a health profession. We sought to understand the ongoing evolution of the nursing profession and the changes that were central to it becoming an intellectual discipline on par with the other health professions in Italy. In 2010, the Regulatory Board of Nursing established a center of excellence to build evidence-based practice, advocate for interdisciplinary health care, and champion health profession reforms for nursing. In this study, focus groups—involving 66 nurse participants from various educational, clinical, and administrative backgrounds—were utilized to better ascertain how the profession has changed. Six themes, three of them metaphors—“vortex,” “leopard spots,” and “deductive jungle”—explain nurses’ experiences of professional change in Italy between 2001 and 2011 and the multiple dimensions that characterize their professional identity and autonomy. PMID:28462290

Clonal Multidrug-Resistant Corynebacterium striatum Strains, Italy

PubMed Central

Campanile, Floriana; Carretto, Edoardo; Barbarini, Daniela; Grigis, Annalisa; Falcone, Marco; Goglio, Antonio; Venditti, Mario

2009-01-01

We assessed the clinical relevance and performed molecular characterization of 36 multidrug-resistant strains of Corynebacterium striatum. Pulsed-field gel electrophoresis confirmed a single clone, possessing erm(X), tetA/B, cmxA/B, and aphA1 genes, but few related subclones. This strain is emerging as a pathogen in Italy. PMID:19116057

The Child Health Care System in Italy.

PubMed

Corsello, Giovanni; Ferrara, Pietro; Chiamenti, Gianpietro; Nigri, Luigi; Campanozzi, Angelo; Pettoello-Mantovani, Massimo

2016-10-01

Pediatric care in Italy has been based during the last 40 years on the increased awareness of the importance of meeting the psychosocial and developmental needs of children and of the role of families in promoting the health and well-being of their children. The pediatric health care system in Italy is part of the national health system. It is made up of 3 main levels of intervention: first access/primary care, secondary care/hospital care, and tertiary care based on specialty hospital care. This overview will also include a brief report on neonatal care, pediatric preventive health care, health service accreditation programs, and postgraduate training in pediatrics. The quality of the Italian child health care system is now considered to be in serious danger because of the restriction of investments in public health caused both by the 2008 global and national economic crisis and by a reduction of the pediatric workforce as a result of progressively insufficient replacement of specialists in pediatrics. Copyright © 2016 Elsevier Inc. All rights reserved.

Boot of Italy taken during Expedition Six

NASA Image and Video Library

2003-02-25

ISS006-E-33736 (25 February 2003) --- The boot of Italy crosses the image in this southwest-looking view taken by an Expedition Six crewmember onboard the International Space Station (ISS). The spine of Italy is highlighted with snow and the largely cloud-covered Mediterranean Sea is at the top. The Adriatic Sea transverses most of the bottom of the image and Sicily appears top left beyond the toe of the boot. The heel lies out of the left side of the image. Corsica and Sardinia appear right of center partly under cloud. The floor of the Po River valley, lower right, is obscured by haze. Experience gained from similar haze events, in which atmospheric pressure, humidity and visibility and atmospheric chemistry were known, suggests that the haze as industrial smog. Industrial haze from the urban region of the central and upper Po valley accumulates to visible concentrations under conditions of high atmospheric pressure and the surrounding mountains prevent easy dispersal. This view illustrates the markedly different color and texture of cloud versus industrial aerosol haze.

History and updating on the spread of Aedes albopictus in Italy.

PubMed

Romi, R

1995-12-01

The present distribution in Italy of Aedes albopictus, the Asian mosquito recently introduced, is described. Until now this mosquito species has been established in 8 regions of our country: Liguria, Veneto, Lazio, Lombardia, Emilia-Romagna, Toscana, Piemonte and recently Sardegna. The established populations have been able to overcome the winter season. These populations, certainly imported from temperate areas, have reconfirmed the great adaptation of the species, reaching the high latitude of 46 degrees North of the Padova area in Northern Italy. The origin of the infestation in Veneto region was shown to be strictly related to the importation of used tires and demonstrated at least for one load of tires from USA. The internal trading of tires from Veneto is the source of infestation of the other Italian regions, with the exception of Liguria and Lazio. Since the introduction and the establishment of Ae. albopictus in Italy represent a new problem of public health, a centre for the surveillance and control of this species has been set up at the Department of Parasitology, Istituto Superiore di Sanità, Roma.

Exposure to vector-borne pathogens in candidate blood donor and free-roaming dogs of northeast Italy.

PubMed

Vascellari, Marta; Ravagnan, Silvia; Carminato, Antonio; Cazzin, Stefania; Carli, Erika; Da Rold, Graziana; Lucchese, Laura; Natale, Alda; Otranto, Domenico; Capelli, Gioia

2016-06-29

Many vector-borne pathogens including viruses, bacteria, protozoa and nematodes occur in northeast Italy, representing a potential threat to animal and human populations. Little information is available on the circulation of the above vector-borne pathogens in dogs. This work aims to (i) assess exposure to and circulation of pathogens transmitted to dogs in northeast Italy by ticks, sandflies, and mosquitoes, and (ii) drive blood donor screening at the newly established canine blood bank of the Istituto Zooprofilattico Sperimentale delle Venezie. Blood samples from 150 privately-owned canine candidate blood donors and 338 free-roaming dogs were screened by serology (IFA for Leishmania infantum, Ehrlichia canis, Anaplasma phagocythophilum, Babesia canis, Rickettsia conorii, R. rickettsii), microscopic blood smear examination, and blood filtration for Dirofilaria spp. All candidate donors and seropositive free-roaming dogs were tested by PCR for L. infantum, E. canis, A. phagocythophilum, Babesia/Theileria and Rickettsia spp. The dogs had no clinical signs at the time of sampling. Overall, 40 candidate donors (26.7 %) and 108 free-roaming dogs (32 %) were seroreactive to at least one vector-borne pathogen. Seroprevalence in candidate donors vs free-roaming dogs was: Leishmania infantum 6.7 vs 7.1 %; Anaplasma phagocytophilum 4.7 vs 3.3 %; Babesia canis 1.3 vs 2.7 %; Ehrlichia canis none vs 0.9 %; Rickettsia conorii 16 vs 21.3 % and R. rickettsii 11 vs 14.3 %. Seroreactivity to R. rickettsii, which is not reported in Italy, is likely a cross-reaction with other rickettsiae. Filariae, as Dirofilaria immitis (n = 19) and D. repens (n = 2), were identified in free-roaming dogs only. No significant differences were observed between candidate donors and free-roaming dogs either in the overall seroprevalence of vector-borne pathogens or for each individual pathogen. All PCRs and smears performed on blood were negative. This study demonstrated that dogs are

34 CFR 694.18 - What requirements must be met by a Partnership or State participating in GEAR UP with respect to...

Code of Federal Regulations, 2014 CFR

2014-07-01

... participating in GEAR UP with respect to 21st Century Scholarship Certificates? 694.18 Section 694.18 Education... to 21st Century Scholarship Certificates? (a) A State or Partnership must provide, in accordance with... GEAR UP project. (b) 21st Century Scholarship Certificates must be personalized and indicate the amount...

34 CFR 694.18 - What requirements must be met by a Partnership or State participating in GEAR UP with respect to...

Code of Federal Regulations, 2012 CFR

2012-07-01

... participating in GEAR UP with respect to 21st Century Scholarship Certificates? 694.18 Section 694.18 Education... to 21st Century Scholarship Certificates? (a) A State or Partnership must provide, in accordance with... GEAR UP project. (b) 21st Century Scholarship Certificates must be personalized and indicate the amount...

34 CFR 694.18 - What requirements must be met by a Partnership or State participating in GEAR UP with respect to...

Code of Federal Regulations, 2013 CFR

2013-07-01

... participating in GEAR UP with respect to 21st Century Scholarship Certificates? 694.18 Section 694.18 Education... to 21st Century Scholarship Certificates? (a) A State or Partnership must provide, in accordance with... GEAR UP project. (b) 21st Century Scholarship Certificates must be personalized and indicate the amount...

34 CFR 694.18 - What requirements must be met by a Partnership or State participating in GEAR UP with respect to...

Code of Federal Regulations, 2011 CFR

2011-07-01

... participating in GEAR UP with respect to 21st Century Scholarship Certificates? 694.18 Section 694.18 Education... to 21st Century Scholarship Certificates? (a) A State or Partnership must provide, in accordance with... GEAR UP project. (b) 21st Century Scholarship Certificates must be personalized and indicate the amount...

Who Cares for Me? Grandparents, Nannies and Babysitters Caring for Children in Contemporary Italy

ERIC Educational Resources Information Center

Sarti, Raffaella

2010-01-01

This paper illustrates the factors and features of the revival of paid care and domestic work in Italy. While Italy is experiencing a boom in the recourse to carers for the elderly, there is not a corresponding expansion in paid private childcare, in spite of growing female employment and limited public services for children. One of the reasons…

{Linking permeability and mechanical damage for basalt from Mt Etna Volcano, Italy}

NASA Astrophysics Data System (ADS)

Faoro, I.; Vinciguerra, S.; Marone, C.; Elsworth, D.

2009-04-01

Volcanic edifices, such as Mt. Etna volcano (Italy), are affected from repeated episodes of pressurisation due to magma emplacement from deep reservoirs to shallow depths. This mechanism pressurizes the large aquifers within the edifice and increases the level of crack damage within the rocks of the edifice over extended periods of times. In order to improve our understanding of the complex coupling between circulating fluids and the development of crack damage, we performed flow-through tests using cylindrical cores of Etna Basalt (Etna, Italy) to evaluate permeabilty changes as a function of approach to failure under non-hydrostatic stresses at confining pressures from 5 to 60 MPa. Samples were loaded to failure by increasing increments of axial stress or by cyclic stresses of increasing amplitude. Both intact samples and pre-drilled samples (1.18mm) were tested. Under hydrostatic stresses, the permeability values of the intact sample decrease linearly with the increments of pressure and range between 5.2*10-17 m2and 1.5*10-17m2Under non-hydrostatic conditions, at low deviatoric stresses from (up to 18 MPa), the permeability values ranged between 5.5*10-17 m2and 4*10-17m2 and tended to completely recover the initial value each time the sample was unloaded, indicating an elastic regime. At higher deviatoric stresses (up to 60 MPa) the permeability values range between 2*10-17 m2 and 0.6*10-17m2. We hypothesize that from 5MPa to 40MPa axial stress, anelastic deformation mechanisms start to occur, with progressive pore collapse and opening of microfractures, resulting in a change of permeability. Under incremental uniaxial cyclic loading up to peak stresses of 160 MPa permeability decreases up to 2 orders of magnitude from initial values of 1*10-15 m2 to 2*10-14m2 Higher initial permeability values are related to the presence of an open fracture in the sample. We interpreted the reduction as a result of progressive closure of the voids space, as the axial load is

76 FR 58299 - Brass Sheet and Strip From France, Germany, Italy, and Japan; Scheduling of a Full Five-Year...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-20

...)] Brass Sheet and Strip From France, Germany, Italy, and Japan; Scheduling of a Full Five-Year Review Concerning the Antidumping Duty Order on Brass Sheet and Strip From France, Germany, Italy, and Japan AGENCY... strip from France, Germany, Italy, and Japan would be likely to lead to continuation or recurrence of...

Epidemiology of malignant mesothelioma in Italy: surveillance systems, territorial clusters and occupations involved

PubMed Central

Binazzi, Alessandra; Bonafede, Michela; Di Marzio, Davide; Scarselli, Alberto

2018-01-01

Background As a legacy of the large asbestos consumption until the definitive ban in 1992, Italy is currently suffering a severe epidemic of asbestos related diseases. The aim of this paper is to describe the surveillance system for mesothelioma incidence and to provide evidences regarding the occurrence of the disease in Italy and the circumstances of asbestos exposure. Methods Italian National Register of Malignant Mesotheliomas (ReNaM) is a permanent surveillance system of mesothelioma incidence, with Regional Operating Centres (CORs) active in each Italian region, identifying incident malignant mesothelioma (MM) cases from health care structures. Occupational history, lifestyle habits and residential history are obtained using a standardised questionnaire, administered by a trained interviewer, to the subject or to the next of kin. Descriptive epidemiological figures, occupations involved in exposures and territorial maps of MM cases have been produced. Results At December 2016, ReNaM has collected 27,356 MM cases for the incidence period between 1993 and 2015. The modalities of exposure to asbestos have been investigated for 21,387 (78%) and an occupational exposure has been defined for around 70% of interviewed cases (14,818). Non-occupational exposure is still relevant with 4.9% and 4.4% of cases for which respectively a familial exposure (due to the cohabitation with an occupational exposed subject) and an environmental exposure (due to the residence near a contaminated site) has been detected. Discussion The epidemiological surveillance of MM incident cases, by the means of a national register for estimating the occurrence of the disease and identifying the circumstances of asbestos exposure, is a relevant tool for preventing asbestos exposure, for supporting the effectiveness of insurance system and for estimating reliable epidemiological figures. PMID:29507789

Dynamic model of Italy`s Progetto Energia cogeneration plants aims to better predict plant performance, cut start-up costs

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-12-31

Over the next four years, the Progetto Energia project will be building several cogeneration plants to help satisfy the increasing demands of Italy`s industrial users and the country`s demand for electrical power. Located at six different sites within Italy, these combined-cycle cogeneration plants will supply a total of 500 MW of electricity and 100 tons/hr of process steam to Italian industries and residences. To ensure project success, a dynamic model of the 50-MW base unit was developed. The goal established for the model was to predict the dynamic behavior of the complex thermodynamic system in order to assess equipment performancemore » and control system effectiveness for normal operation and, more importantly, abrupt load changes. In addition to fulfilling its goals, the dynamic study guided modifications to controller logic that significantly improved steam drum pressure control and bypassed steam desuperheating performance simulations of normal and abrupt transient events allowed engineers to define optimum controller gain coefficients. The dynamic study will undoubtedly reduce the associated plant start-up costs and contribute to a smooth commercial plant acceptance. As a result of the work, the control system has already been through its check-out and performance evaluation, usually performed during the plant start-up phase. Field engineers will directly benefit from this effort to identify and resolve control system {open_quotes}bugs{close_quotes} before the equipment reaches the field. High thermal efficiency, rapid dispatch and high plant availability were key reasons why the natural gas combined-cycle plant was chosen. Other favorable attributes of the combined-cycle plant contributing to the decision were: Minimal environmental impact; a simple and effective process and control philosophy to result in safe and easy plant operation; a choice of technologies and equipment proven in a large number of applications.« less

Bay of Naples, Italy

NASA Image and Video Library

1981-04-14

STS001-13-442 (14 April 1981) --- This photograph showing much of Italy was taken with a handheld 70mm camera from 276 kilometers above Earth as the NASA space shuttle Columbia and its crew were marking their last few hours in space on the historic first space mission utilizing a reusable vehicle. Included in the area of the frame are Golfo de Napoli, Napoli (Naples), Castellammare, Amalfi, Capri, Sorrento, Mt. Vesuvius and the ruins of Pompei. Astronauts John W. Young and Robert L. Crippen exposed eight magazines of color 70mm film during their two and one-third days in Earth orbit. Photo credit: NASA

IL-18 Serum Level in Adult Onset Still's Disease: A Marker of Disease Activity

PubMed Central

Colafrancesco, Serena; Priori, Roberta; Alessandri, Cristiano; Perricone, Carlo; Pendolino, Monica; Picarelli, Giovanna; Valesini, Guido

2012-01-01

Introduction. Immunological factors seem to play a pivotal role in Adult Onset Still's Disease (AOSD). Among all, IL-18 cytokine is overexpressed and drives the inflammatory process. Objective. We aimed to investigate the levels of IL-18 in sera of Italian patients with AOSD and to assess its possible role as a marker of disease activity. Methods. IL-18 serum levels were determined by ELISA in 26 Italian patients with AOSD. Disease activity was assessed using Pouchot's criteria. As controls, 21 patients with Rheumatoid Arthritis (RA), 21 patients with Sjogren's Syndrome (SS), 20 patients with Systemic Lupus Erythematosus (SLE), and 21 healthy subjects (normal human sera, NHS) were evaluated. Results. IL-18 serum levels were significantly higher in patients with active AOSD than in non-active (P = 0.001) and control groups (RA P = 0.0070, SS P = 0.0029, SLE P = 0.0032, NHS P = 0.0004). A significant correlation between IL-18 serum levels and disease activity (P < 0.0001), and laboratory parameters as ferritin (P = 0.0127) and C-reactive protein (P = 0.0032) was demonstrated. Conclusions. Higher levels of IL-18 are detected in active AODS patients and correlate with disease activity and inflammatory laboratory features. ROC-AUC analysis of the serum concentration of IL-18 suggests that it can be considered a diagnostic marker of AOSD. This paper supports the targeting of this cytokine as a possible therapeutic option in AOSD. PMID:22762008