Science.gov

Sample records for concept refinement plan

  1. The psychometric refinement of the Materials Concept Inventory (MCI)

    NASA Astrophysics Data System (ADS)

    Corkins, James

    The purpose of this study was to evaluate the psychometric properties of the Materials Concept Inventory (MCI) and then recommend revisions. The MCI was administered to a sample of 303 undergraduate engineering students enrolled in a materials engineering course taught by an instructor unrelated to this study. The MCI demonstrated adequate reliability (Cronbach's alpha was .73) and strong discriminatory power (Ferguson's delta was 0.96). A pretest MCI was given only two days into the course and was able to predict the final course grade (r = .30, p < .001). Convergent validity was also established by significantly correlating a post-test version of the MCI with the final course grade (r = .50, p < .001). Nineteen of the thirty items on the MCI met the criterion for index of item congruency, demonstrating somewhat mixed reviews by content experts. A confirmatory factor analysis conducted on the initial MCI structure failed to support a six-factor model. A revision was made to the structure of the MCI, whereby an exploratory and subsequent confirmatory factor analysis yielded a refined six-factor structure that did provide a strong fit by the empirical data [chi-squared (194) = 196.03, p = .426; and root mean square error approximation (RMSEA) was .007; and comparative fit index (CFI) was .996]. The Cronbach's alpha of the refined-MCI was 0.75, suggesting 'good' reliability. The six factors could only be interpreted by an integration of cognitive processes with content. Those six factors were labeled: (1) compare and contrast ductile and brittle material, (2) analyze structure and how it changes due to defects arising from stretching, (3) understand and analyze the structure and properties of glass, (4) analyze structure and how it changes due to defects arising from bending, (5) understand and analyze the structure and properties of metals, and (6) synthesize and apply graphs and proportions with relation to various materials engineering concepts. Results related to

  2. Proof of concept test and evaluation, Lasentec refining sensor

    SciTech Connect

    Anderson, J.E.

    1991-07-01

    The Scanning Laser Microscopes (SLM) LAB-TEC 150 and PAR-TEC 200, were evaluated as instruments for monitoring fiber development during refining. The LAB-TEC 150 did not produce repeatable results which could be related to fiber development, as measured by Canadian Standard Freeness or hand sheet physical strength properties. The PAR-TEC 200 was found to correlate to strength development (Burst and Tensile Indices) during the first stages of laboratory Valley beating of bleached hardwood and softwood pulps. Preliminary testing of the PAR-TEC 200 in a pilot scale refining circuit was inconclusive. The influence of several process variables on instrument readings was investigated including flow rate, probe position and consistency. It is likely that a dual sensor system would be required in a commercial mill environment, to eliminate the effect of process variables. The next phase of the evaluation and development program will include two investigations: (1) A more scientific evaluation of which changes in fiber morphology the sensor is detecting during refining, and (2) a continuation of the in-line development; with a goal of eliminating process flow variables, and more accurately monitoring fiber development, by the use of two sensors, one before and after refining.

  3. Commentary--Enlarging Concepts, Refining Methods, Improving Interventions

    ERIC Educational Resources Information Center

    Palacios, Jesús

    2015-01-01

    As illustrated by the articles in this special issue, the research into ethnic identity in adoption is making significant progress. At the same time, it faces new challenges in the definition of concepts, the use of appropriate methods of study, and the consideration of implications for professional interventions. This commentary offers additional…

  4. Proof of concept test and evaluation, Lasentec refining sensor

    SciTech Connect

    Anderson, J.E.

    1991-05-01

    The PAR-TEC 100, a particle size analyzer manufactured by Lasentec, Inc., is being evaluated as a sensor for in-line monitoring of fiber development during refining. The approach used is to beat softwood pulp in a Valley beater to produce a three point beater curve and to compare PAR-TEC measurements on those samples with Canadian Standard Freeness, Kajaani fiber length and coarseness, as well as tensile, wet tensile and tear strength. There is a very good positive correlation between PAR-TEC 100 scan counts mean size and tensile index; and a strong negative correlation to Canadian standard freeness, and Kajaani fiber length when evaluating Valley beater fiber development. There is a positive relation between the results of analyzing the individual Bauer-McNett fiber fractions with both the Kajaani 100 and PAR-TEC 100. These results indicate that the PAR-TEC 100 measures a complex value of fiber size, which under the correct circumstances is directly related to Kajaani arithmetic average fiber length. 16 figs.

  5. Observation Plan for Refining Shape Model of (6) HEBE

    NASA Astrophysics Data System (ADS)

    Lu, Xiaoping; Zhao, Haibin; You, Zhong

    2013-02-01

    As the number of observatories located on the surface of Earth is increasing largely in decades more and more photometric data of asteroids is observed to make the research about their various physical and chemical characteristics. Compared with hundreds of thousands of asteroids found up to now, rare hundreds of three-dimensional shape models of asteroids have been built from the tremendous photometric data with incessant observations, i.e. lightcurves. For some specific asteroid already with many observed lightcurves, the unceasing observation is not too much valuable, nevertheless an additional lightcurve observed in a request viewing aspect can refine the shape model and other related parameters. This article taking the asteroid (6) HEBE for example, attempts to introduce a method to make the observation plan by combining the request of the shape model and the orbital limitation of asteroids. Through analyzing the distribution of lightcurves of (6) HEBE, small cabins without any lightcurve data are found, which can be filled by new observations at some specified dates when the positions of Asteroid, Sun, Earth are limited as the request geometry.

  6. Energy Planning: A Total Concept.

    ERIC Educational Resources Information Center

    Hall, Stephen S. J.

    1975-01-01

    Harvard's energy conservation plan is presented in detail with the hope that it will suggest practical, cost-effective energy-saving ideas to other institutions, and to dispel frequently-expressed fears concerning the feasibility and acceptance problems of this type of program. The total energy plan incorporates numerous specific elements that…

  7. Alternative Training Using Selected Program Planning Concepts.

    ERIC Educational Resources Information Center

    Zappala, John

    1996-01-01

    Discusses a study to determine the extent that Michigan Adult Education Alternative Training (AEAT) providers used selected concepts of systematic planning in developing training programs. Finds that 55.6% of 65 responding AEAT planners utilized the concepts. Suggests that planners should also incorporate political and practical considerations.…

  8. Improving IMRT-plan quality with MLC leaf position refinement post plan optimization

    PubMed Central

    Niu, Ying; Zhang, Guowei; Berman, Barry L.; Parke, William C.; Yi, Byongyong; Yu, Cedric X.

    2012-01-01

    Purpose: In intensity-modulated radiation therapy (IMRT) planning, reducing the pencil-beam size may lead to a significant improvement in dose conformity, but also increase the time needed for the dose calculation and plan optimization. The authors develop and evaluate a postoptimization refinement (POpR) method, which makes fine adjustments to the multileaf collimator (MLC) leaf positions after plan optimization, enhancing the spatial precision and improving the plan quality without a significant impact on the computational burden. Methods: The authors’ POpR method is implemented using a commercial treatment planning system based on direct aperture optimization. After an IMRT plan is optimized using pencil beams with regular pencil-beam step size, a greedy search is conducted by looping through all of the involved MLC leaves to see if moving the MLC leaf in or out by half of a pencil-beam step size will improve the objective function value. The half-sized pencil beams, which are used for updating dose distribution in the greedy search, are derived from the existing full-sized pencil beams without need for further pencil-beam dose calculations. A benchmark phantom case and a head-and-neck (HN) case are studied for testing the authors’ POpR method. Results: Using a benchmark phantom and a HN case, the authors have verified that their POpR method can be an efficient technique in the IMRT planning process. Effectiveness of POpR is confirmed by noting significant improvements in objective function values. Dosimetric benefits of POpR are comparable to those of using a finer pencil-beam size from the optimization start, but with far less computation and time. Conclusions: The POpR is a feasible and practical method to significantly improve IMRT-plan quality without compromising the planning efficiency. PMID:22894437

  9. Learning and plan refinement in a knowledge-based system for automatic speech recognition

    SciTech Connect

    De Mori, R.; Lam, L.; Gilloux, M.

    1987-03-01

    This paper shows how a semiautomatic design of a speech recognition system can be done as a planning activity. Recognition performances are used for deciding plan refinement. Inductive learning is performed for setting action preconditions. Experimental results in the recognition of connected letters spoken by 100 speakers are presented.

  10. A mission planning concept and mission planning system for future manned space missions

    NASA Technical Reports Server (NTRS)

    Wickler, Martin

    1994-01-01

    The international character of future manned space missions will compel the involvement of several international space agencies in mission planning tasks. Additionally, the community of users requires a higher degree of freedom for experiment planning. Both of these problems can be solved by a decentralized mission planning concept using the so-called 'envelope method,' by which resources are allocated to users by distributing resource profiles ('envelopes') which define resource availabilities at specified times. The users are essentially free to plan their activities independently of each other, provided that they stay within their envelopes. The new developments were aimed at refining the existing vague envelope concept into a practical method for decentralized planning. Selected critical functions were exercised by planning an example, founded on experience acquired by the MSCC during the Spacelab missions D-1 and D-2. The main activity regarding future mission planning tasks was to improve the existing MSCC mission planning system, using new techniques. An electronic interface was developed to collect all formalized user inputs more effectively, along with an 'envelope generator' for generation and manipulation of the resource envelopes. The existing scheduler and its data base were successfully replaced by an artificial intelligence scheduler. This scheduler is not only capable of handling resource envelopes, but also uses a new technology based on neuronal networks. Therefore, it is very well suited to solve the future scheduling problems more efficiently. This prototype mission planning system was used to gain new practical experience with decentralized mission planning, using the envelope method. In future steps, software tools will be optimized, and all data management planning activities will be embedded into the scheduler.

  11. A formal concept analysis and semantic query expansion cooperation to refine health outcomes of interest

    PubMed Central

    2015-01-01

    Background Electronic Health Records (EHRs) are frequently used by clinicians and researchers to search for, extract, and analyze groups of patients by defining Health Outcome of Interests (HOI). The definition of an HOI is generally considered a complex and time consuming task for health care professionals. Methods In our clinical note-based pharmacovigilance research, we often operate upon potentially hundreds of ontologies at once, expand query inputs, and we also increase the search space over clinical text as well as structured data. Such a method implies to specify an initial set of seed concepts, which are based on concept unique identifiers. This paper presents a novel method based on Formal Concept Analysis (FCA) and Semantic Query Expansion (SQE) to assist the end-user in defining their seed queries and in refining the expanded search space that it encompasses. Results We evaluate our method over a gold-standard corpus from the 2008 i2b2 Obesity Challenge. This experimentation emphasizes positive results for sensitivity and specificity measures. Our new approach provides better recall with high precision of the obtained results. The most promising aspect of this approach consists in the discovery of positive results not present our Obesity NLP reference set. Conclusions Together with a Web graphical user interface, our FCA and SQE cooperation end up being an efficient approach for refining health outcome of interest using plain terms. We consider that this approach can be extended to support other domains such as cohort building tools. PMID:26043839

  12. Life cycle planning: An evolving concept

    SciTech Connect

    Moore, P.J.R.; Gorman, I.G.

    1994-12-31

    Life-cycle planning is an evolving concept in the management of oil and gas projects. BHP Petroleum now interprets this idea to include all development planning from discovery and field appraisal to final abandonment and includes safety, environmental, technical, plant, regulatory, and staffing issues. This article describes in the context of the Timor Sea, how despite initial successes and continuing facilities upgrades, BHPP came to perceive that current operations could be the victim of early development successes, particularly in the areas of corrosion and maintenance. The search for analogies elsewhere lead to the UK North Sea, including the experiences of Britoil and BP, both of which performed detailed Life of Field studies in the later eighties. These materials have been used to construct a format and content for total Life-cycle plans in general and the social changes required to ensure their successful application in Timor Sea operations and deployment throughout Australia.

  13. Treatment planning concepts for the ageing patient.

    PubMed

    Ettinger, R L

    2015-03-01

    There is an ageing imperative in Australia as in many other industrialized nations, and these populations are extremely heterogeneous. In young adults, the factors which influence decision making for oral health care are whether the patient has the will, the time or the finances to pay for care, while for clinicians, the decisions are whether they have the skill and the resources to carry out the treatment plan. For older adults, the decision making includes all of the previous identified factors, but they are now complicated by the patient's medical and medication problems, the side effects of the medications they are taking, their cognitive status as well as the cumulative effects of a lifetime of physiological, traumatic and iatrogenic effects on the dentition and the oral cavity. The decision-making process which has evolved has been called many names, from cost-effective care to minimal invasive dentistry to rational dental care. Fundamentally, they are similar. Rational dental care has been defined as the process of decision making, which develops a treatment plan that is in the best interest of the patient after evaluating all of the modifying factors. This article will discuss the various concepts, and the strengths and weaknesses of some of these systems. It will also illustrate some of the clinical problems as there is very little evidence-based data to support any of these concepts. However, treatment planning is still an art, which can only be carried out for an individual and not a group, and the result must serve the needs of the patient and enhance the quality of his or her life. PMID:25762044

  14. Mesh generation/refinement using fractal concepts and iterated function systems

    NASA Technical Reports Server (NTRS)

    Bova, S. W.; Carey, G. F.

    1992-01-01

    A novel method of mesh generation is proposed which is based on the use of fractal concepts to derive contractive, affine transformations. The transformations are constructed in such a manner that the attractors of the resulting maps are a union of the points, lines and surfaces in the domain. In particular, the mesh nodes may be generated recursively as a sequence of points which are obtained by applying the transformations to a coarse background mesh constructed from the given boundary data. A Delaunay triangulation or similar edge connection approach can then be performed on the resulting set of nodes in order to generate the mesh. Local refinement of an existing mesh can also be performed using the procedure. The method is easily extended to three dimensions, in which case the Delaunay triangulation is replaced by an analogous 3D tesselation.

  15. Program Planning Concepts in Solid Waste Management

    ERIC Educational Resources Information Center

    Brown, Sanford M., Jr.

    1972-01-01

    Presents a brief review of the program planning process, and uses the example of a solid waste program to illustrate what has or has not been accomplished through the use of the planning process. (LK)

  16. [Evolution and discrimination of ecological planning and its related conceptions].

    PubMed

    He, Xuan; Mao, Hui-ping; Niu, Dong-jie; Bao, Cun-kuan

    2013-08-01

    Ecological planning is one of the most important tools in realizing city's sustainable development. The ecological planning in China was started in the 1980s, and on the basis of assimilating the existing theoretical and practical experiences from western countries, basically formed a theoretical system in accordance with the Chinese characteristics and acquired a series of practical results. This paper reviewed the research and development processes of China' s ecological planning. It is considered that the study of our ecological planning was derived from the geographical principles of land resources ecological utilization, the ecological principles of complex ecological system theory, and the combination of these two principles. The ecological planning has experienced three research stages, i. e., single-disciplinary exploration, multi-disciplinary and multi-perspective study (including landscape ecology, ecology and urban planning), and interdisciplinary and multidisciplinary collaboration research. The ecological planning and the related conceptions, primary principles, main academic points, and representatives at each research stage were summarized, and through the discrimination of the basic conceptions of ecological planning and other related plans, it was pointed out that ecological planning is an general conception which includes land ecological planning, urban ecological planning, and eco-city planning, and the principles and theories of ecological planning should be integrated into, led and restricted the present planning system to promote the city's and regional sustainable development. PMID:24380360

  17. JWST planning and scheduling operations and concepts

    NASA Astrophysics Data System (ADS)

    Kinzel, Wayne M.

    2010-07-01

    The James Webb Space Telescope (JWST) will be a large infrared space observatory in orbit about the Sun-Earth second Lagrange Point. This paper provides an overview of the expected operational requirements imposed by the observatory's basic science activities (imaging, spectroscopy, coronography) and the operational issues associated with interleaving periodic engineering activities (Wave Front Sensing & Control activities, Momentum Unloads, and orbit Station Keeping) with the science observations. The planning and scheduling operations must maximize the overall science integration time while meeting the mission and observer specified constraints. The "Observation," "Visit," and Observation Template constructs are explained in the context of providing an interface to the Observer that provides the ability to specify complex observations, such as mosaics and cluster targets, while also minimizing specification errors and allowing planning and scheduling flexibility of the observations. The expected nominal planning and scheduling process including the creation and maintenance of the Long Range Plan (~1.25 year duration), the Short Term Schedules (~ three weeks), and the on-board Observation Plan (< 10 days) is described. The event-driven on-board operations of JWST and how the planning and scheduling process monitors and reacts to the onboard execution of the Observation Plan are described. Finally, the methods employed to allow for robust interfacing of scheduled real-time operations (for example, Station Keeping) with the Observation Plan and unplanned, but expected, modifications to the Observation Plan (for example, Target of Opportunity) are described.

  18. Proof of concept test and evaluation (pilot/mill testing) of Lasentec refining sensor. Final report

    SciTech Connect

    Anderson, J.E.

    1994-06-03

    On-line measurement of refining development is of vital concern to the papermaker since its control directly affects the uniformity of the product, drainage, drying and energy consumption. The current methods of monitoring fiber development during refining rely on secondary measures such as: Drainage rate, either measured off-line as Canadian standard freeness, or on-line with a number of commercial sample and test devices; energy consumption at the refiner; or changes in vacuum on the paper machine. To overcome these limitations of the existing technology, this project was designed to evaluate the use of a new type of sensor to monitor fiber development during refining. This sensor, a Lasentec Scanning Laser Microscope (SLM), is currently used as a particle size analyzer for slurries. The sensor will be described in more detail later. The use of this sensor had been successful in the laboratory. This project, was to establish this instrument as an in-line means to directly monitor refining.

  19. Productivity enhancement planning using participative management concepts

    NASA Technical Reports Server (NTRS)

    White, M. E.; Kukla, J. C.

    1985-01-01

    A productivity enhancement project which used participative management for both planning and implementation is described. The process and results associated with using participative management to plan and implement a computer terminal upgrade project where the computer terminals are used by research and development (R&D) personnel are reported. The upgrade improved the productivity of R&D personnel substantially, and their commitment of the implementation is high. Successful utilization of participative management for this project has laid a foundation for continued style shift toward participation within the organization.

  20. Concept mapping: reducing clinical care plan paperwork and increasing learning.

    PubMed

    Schuster, P M

    2000-01-01

    The author describes how concept maps were used in place of nursing care plans to reduce care planning paperwork in fundamentals and medical-surgical clinical courses in acute care facilities. In addition to less paperwork, clinical concept mapping enhances students' critical thinking skills and clinical reasoning because students and faculty can clearly and succinctly visualize priorities and identify relationships in clinical patient data. PMID:11052005

  1. 18 CFR 401.2 - Concept of the plan.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Concept of the plan. 401.2 Section 401.2 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION.... It is the Commission's responsibility to adopt the Comprehensive Plan, after consultation with...

  2. 18 CFR 401.2 - Concept of the plan.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Concept of the plan. 401.2 Section 401.2 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION.... It is the Commission's responsibility to adopt the Comprehensive Plan, after consultation with...

  3. 18 CFR 401.2 - Concept of the plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Concept of the plan. 401.2 Section 401.2 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION.... It is the Commission's responsibility to adopt the Comprehensive Plan, after consultation with...

  4. 18 CFR 401.2 - Concept of the plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Concept of the plan. 401.2 Section 401.2 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION.... It is the Commission's responsibility to adopt the Comprehensive Plan, after consultation with...

  5. 18 CFR 401.2 - Concept of the plan.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Concept of the plan. 401.2 Section 401.2 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION.... It is the Commission's responsibility to adopt the Comprehensive Plan, after consultation with...

  6. Resource envelope concepts for mission planning

    NASA Technical Reports Server (NTRS)

    Ibrahim, K. Y.; Weiler, J. D.; Tokaz, J. C.

    1991-01-01

    Seven proposed methods for creating resource envelopes for Space Station Freedom mission planning are detailed. Four reference science activity models are used to illustrate the effect of adding operational flexibility to mission timelines. For each method, a brief explanation is given along with graphs to illustrate the application of the envelopes to the power and crew resources. The benefits and costs of each method are analyzed in terms of resource utilization. In addition to the effect on individual activities, resource envelopes are analyzed at the experiment level.

  7. Enroute flight planning: Evaluating design concepts for the development of cooperative problem-solving concepts

    NASA Technical Reports Server (NTRS)

    Smith, Philip J.; Mccoy, C. Elaine

    1991-01-01

    The goals of this research were to develop design concepts to support the task of enroute flight planning. And within this context, to explore and evaluate general design concepts and principles to guide the development of cooperative problem solving systems. A detailed model is to be developed of the cognitive processes involved in flight planning. Included in this model will be the identification of individual differences of subjects. Of particular interest will be differences between pilots and dispatchers. The effect will be studied of the effect on performance of tools that support planning at different levels of abstraction. In order to conduct this research, the Flight Planning Testbed (FPT) was developed, a fully functional testbed environment for studying advanced design concepts for tools to aid in flight planning.

  8. Auditing complex concepts of SNOMED using a refined hierarchical abstraction network.

    PubMed

    Wang, Yue; Halper, Michael; Wei, Duo; Gu, Huanying; Perl, Yehoshua; Xu, Junchuan; Elhanan, Gai; Chen, Yan; Spackman, Kent A; Case, James T; Hripcsak, George

    2012-02-01

    Auditors of a large terminology, such as SNOMED CT, face a daunting challenge. To aid them in their efforts, it is essential to devise techniques that can automatically identify concepts warranting special attention. "Complex" concepts, which by their very nature are more difficult to model, fall neatly into this category. A special kind of grouping, called a partial-area, is utilized in the characterization of complex concepts. In particular, the complex concepts that are the focus of this work are those appearing in intersections of multiple partial-areas and are thus referred to as overlapping concepts. In a companion paper, an automatic methodology for identifying and partitioning the entire collection of overlapping concepts into disjoint, singly-rooted groups, that are more manageable to work with and comprehend, has been presented. The partitioning methodology formed the foundation for the development of an abstraction network for the overlapping concepts called a disjoint partial-area taxonomy. This new disjoint partial-area taxonomy offers a collection of semantically uniform partial-areas and is exploited herein as the basis for a novel auditing methodology. The review of the overlapping concepts is done in a top-down order within semantically uniform groups. These groups are themselves reviewed in a top-down order, which proceeds from the less complex to the more complex overlapping concepts. The results of applying the methodology to SNOMED's Specimen hierarchy are presented. Hypotheses regarding error ratios for overlapping concepts and between different kinds of overlapping concepts are formulated. Two phases of auditing the Specimen hierarchy for two releases of SNOMED are reported on. With the use of the double bootstrap and Fisher's exact test (two-tailed), the auditing of concepts and especially roots of overlapping partial-areas is shown to yield a statistically significant higher proportion of errors. PMID:21907827

  9. Auditing Complex Concepts of SNOMED using a Refined Hierarchical Abstraction Network

    PubMed Central

    Wang, Yue; Halper, Michael; Wei, Duo; Gu, Huanying; Perl, Yehoshua; Xu, Junchuan; Elhanan, Gai; Chen, Yan; Spackman, Kent A.; Case, James T.; Hripcsak, George

    2012-01-01

    Auditors of a large terminology, such as SNOMED CT, face a daunting challenge. To aid them in their efforts, it is essential to devise techniques that can automatically identify concepts warranting special attention. “Complex” concepts, which by their very nature are more difficult to model, fall neatly into this category. A special kind of grouping, called a partial-area, is utilized in the characterization of complex concepts. In particular, the complex concepts that are the focus of this work are those appearing in intersections of multiple partial-areas and are thus referred to as overlapping concepts. In a companion paper, an automatic methodology for identifying and partitioning the entire collection of overlapping concepts into disjoint, singly-rooted groups, that are more manageable to work with and comprehend, has been presented. The partitioning methodology formed the foundation for the development of an abstraction network for the overlapping concepts called a disjoint partial-area taxonomy. This new disjoint partial-area taxonomy offers a collection of semantically uniform partial-areas and is exploited herein as the basis for a novel auditing methodology. The review of the overlapping concepts is done in a top-down order within semantically uniform groups. These groups are themselves reviewed in a top-down order, which proceeds from the less complex to the more complex overlapping concepts. The results of applying the methodology to SNOMED’s Specimen hierarchy are presented. Hypotheses regarding error ratios for overlapping concepts and between different kinds of overlapping concepts are formulated. Two phases of auditing the Specimen hierarchy for two releases of SNOMED are reported on. With the use of the double bootstrap and Fisher’s exact test (two-tailed), the auditing of concepts and especially roots of overlapping partial-areas is shown to yield a statistically significant higher proportion of errors. PMID:21907827

  10. A distributed planning concept for Space Station payload operations

    NASA Technical Reports Server (NTRS)

    Hagopian, Jeff; Maxwell, Theresa; Reed, Tracey

    1994-01-01

    The complex and diverse nature of the payload operations to be performed on the Space Station requires a robust and flexible planning approach. The planning approach for Space Station payload operations must support the phased development of the Space Station, as well as the geographically distributed users of the Space Station. To date, the planning approach for manned operations in space has been one of centralized planning to the n-th degree of detail. This approach, while valid for short duration flights, incurs high operations costs and is not conducive to long duration Space Station operations. The Space Station payload operations planning concept must reduce operations costs, accommodate phased station development, support distributed users, and provide flexibility. One way to meet these objectives is to distribute the planning functions across a hierarchy of payload planning organizations based on their particular needs and expertise. This paper presents a planning concept which satisfies all phases of the development of the Space Station (manned Shuttle flights, unmanned Station operations, and permanent manned operations), and the migration from centralized to distributed planning functions. Identified in this paper are the payload planning functions which can be distributed and the process by which these functions are performed.

  11. Conservation plan based on the concept of integrity

    NASA Astrophysics Data System (ADS)

    Yen, Y. N.; Cheng, C. F.

    2015-08-01

    Value based concept has been accepted as a universal principle for the conservation of Cultural Heritage. Authenticity and integrity are two main issues protecting those values. Authenticity is the major tool in the value assessment and integrity plays an important role in the procedure of conservation plan. From the perspective of integrity, this research explores the principle of conservation plan and discusses its relation with the restoration plan and urban plan. A conservation plan in Quing-Lin village, Kinmen, will be taken as an example for implementation. The research shows that a conservation plan with integrity in mind helps to clarify the conservation target areas and their buffer zones. It also serves as a tool for developing control and risk management. Cultural mapping is an efficient tool for the communication with stakeholders in the process of the conservation plan.

  12. Design and analysis of advanced flight planning concepts

    NASA Technical Reports Server (NTRS)

    Sorensen, John A.

    1987-01-01

    The objectives of this continuing effort are to develop and evaluate new algorithms and advanced concepts for flight management and flight planning. This includes the minimization of fuel or direct operating costs, the integration of the airborne flight management and ground-based flight planning processes, and the enhancement of future traffic management systems design. Flight management (FMS) concepts are for on-board profile computation and steering of transport aircraft in the vertical plane between a city pair and along a given horizontal path. Flight planning (FPS) concepts are for the pre-flight ground based computation of the three-dimensional reference trajectory that connects the city pair and specifies the horizontal path, fuel load, and weather profiles for initializing the FMS. As part of these objectives, a new computer program called EFPLAN has been developed and utilized to study advanced flight planning concepts. EFPLAN represents an experimental version of an FPS. It has been developed to generate reference flight plans compatible as input to an FMS and to provide various options for flight planning research. This report describes EFPLAN and the associated research conducted in its development.

  13. Thirty Meter Telescope: current operations concepts and plans

    NASA Astrophysics Data System (ADS)

    Silva, David R.

    2008-07-01

    The Thirty Meter Telescope (TMT) will be a ground-based, 30-m optical-IR telescope with a highly segmented primary mirror located in a remote location. From the start of operations, TMT will provide a rich and diverse mix of seeing-limited and diffraction-limited instrumentation. Initially, only classical observing will be supported, although remote observing will follow almost immediately. Queue (or service) observing may be supported at a later date. TMT users will expect high facility uptime and observing efficiency as well as effective user support for planning and execution of observations. Those expectations are captured in the high-level Operations Concept Definition (OCD) document. The services and staffing needed to implement those concepts are described in the TMT Operations Plan. In this paper, high-level TMT operational concepts are summarized followed by a description of the current operations plan, including staffing model.

  14. Generic mission planning concepts for space astronomy missions

    NASA Technical Reports Server (NTRS)

    Guffin, O. T.; Onken, J. F.

    1993-01-01

    The past two decades have seen the rapid development of space astronomy, both manned and unmanned, and the concurrent proliferation of the operational concepts and software that have been produced to support each individual project. Having been involved in four of these missions since the '70's and three yet to fly in the present decade, the authors believe it is time to step back and evaluate this body of experience from a macro-systems point of view to determine the potential for generic mission planning concepts that could be applied to future missions. This paper presents an organized evaluation of astronomy mission planning functions, functional flows, iteration cycles, replanning activities, and the requirements that drive individual concepts to specific solutions. The conclusions drawn from this exercise are then used to propose a generic concept that could support multiple missions.

  15. The 3D Recognition, Generation, Fusion, Update and Refinement (RG4) Concept

    NASA Technical Reports Server (NTRS)

    Maluf, David A.; Cheeseman, Peter; Smelyanskyi, Vadim N.; Kuehnel, Frank; Morris, Robin D.; Norvig, Peter (Technical Monitor)

    2001-01-01

    This paper describes an active (real time) recognition strategy whereby information is inferred iteratively across several viewpoints in descent imagery. We will show how we use inverse theory within the context of parametric model generation, namely height and spectral reflection functions, to generate model assertions. Using this strategy in an active context implies that, from every viewpoint, the proposed system must refine its hypotheses taking into account the image and the effect of uncertainties as well. The proposed system employs probabilistic solutions to the problem of iteratively merging information (images) from several viewpoints. This involves feeding the posterior distribution from all previous images as a prior for the next view. Novel approaches will be developed to accelerate the inversion search using novel statistic implementations and reducing the model complexity using foveated vision. Foveated vision refers to imagery where the resolution varies across the image. In this paper, we allow the model to be foveated where the highest resolution region is called the foveation region. Typically, the images will have dynamic control of the location of the foveation region. For descent imagery in the Entry, Descent, and Landing (EDL) process, it is possible to have more than one foveation region. This research initiative is directed towards descent imagery in connection with NASA's EDL applications. Three-Dimensional Model Recognition, Generation, Fusion, Update, and Refinement (RGFUR or RG4) for height and the spectral reflection characteristics are in focus for various reasons, one of which is the prospect that their interpretation will provide for real time active vision for automated EDL.

  16. Investigating Further Preservice Teachers' Conceptions of Multidigit Whole Numbers: Refining a Framework

    ERIC Educational Resources Information Center

    Thanheiser, Eva

    2010-01-01

    This study was designed to investigate preservice elementary school teachers' (PSTs') responses to written standard place-value-operation tasks (addition and subtraction). Previous research established that PSTs can often perform but not explain algorithms and provided a four-category framework for PSTs' conceptions, two correct and two incorrect.…

  17. Integrating Strategic Planning Concepts into the Negotiating Process.

    ERIC Educational Resources Information Center

    Winer, Toby R.; Winer, Russell S.

    1987-01-01

    The purchase of a new telecommunications system at Vanderbilt University is described. By understanding conditions in which buyers generally obtain leverage over sellers in industries, it was possible to improve negotiating power. Strategic-planning concepts developed by Michael Porter in his book "Competitive Strategy" were used as a guide. (MLW)

  18. Dependence of Achievable Plan Quality on Treatment Technique and Planning Goal Refinement: A Head-and-Neck Intensity Modulated Radiation Therapy Application

    SciTech Connect

    Qi, X. Sharon Ruan, Dan; Lee, Steve P.; Pham, Andrew; Kupelian, Patrick; Low, Daniel A.; Steinberg, Michael; Demarco, John

    2015-03-15

    Purpose: To develop a practical workflow for retrospectively analyzing target and normal tissue dose–volume endpoints for various intensity modulated radiation therapy (IMRT) delivery techniques; to develop technique-specific planning goals to improve plan consistency and quality when feasible. Methods and Materials: A total of 165 consecutive head-and-neck patients from our patient registry were selected and retrospectively analyzed. All IMRT plans were generated using the same dose–volume guidelines for TomoTherapy (Tomo, Accuray), TrueBeam (TB, Varian) using fixed-field IMRT (TB-IMRT) or RAPIDARC (TB-RAPIDARC), or Siemens Oncor (Siemens-IMRT, Siemens). A MATLAB-based dose–volume extraction and analysis tool was developed to export dosimetric endpoints for each patient. With a fair stratification of patient cohort, the variation of achieved dosimetric endpoints was analyzed among different treatment techniques. Upon identification of statistically significant variations, technique-specific planning goals were derived from dynamically accumulated institutional data. Results: Retrospective analysis showed that although all techniques yielded comparable target coverage, the doses to the critical structures differed. The maximum cord doses were 34.1 ± 2.6, 42.7 ± 2.1, 43.3 ± 2.0, and 45.1 ± 1.6 Gy for Tomo, TB-IMRT, TB-RAPIDARC, and Siemens-IMRT plans, respectively. Analyses of variance showed significant differences for the maximum cord doses but no significant differences for other selected structures among the investigated IMRT delivery techniques. Subsequently, a refined technique-specific dose–volume guideline for maximum cord dose was derived at a confidence level of 95%. The dosimetric plans that failed the refined technique-specific planning goals were reoptimized according to the refined constraints. We observed better cord sparing with minimal variations for the target coverage and other organ at risk sparing for the Tomo cases, and higher

  19. New Concepts for Refinement of Cumulus Parameterization in GCM's the Arakawa-Schubert Framework

    NASA Technical Reports Server (NTRS)

    Sud, Y. C.; Walker, G. K.; Lau, William (Technical Monitor)

    2002-01-01

    Several state-of-the-art models including the one employed in this study use the Arakawa-Schubert framework for moist convection, and Sundqvist formulation of stratiform. clouds, for moist physics, in-cloud condensation, and precipitation. Despite a variety of cloud parameterization methodologies developed by several modelers including the authors, most of the parameterized cloud-models have similar deficiencies. These consist of: (a) not enough shallow clouds, (b) too many deep clouds; (c) several layers of clouds in a vertically demoralized model as opposed to only a few levels of observed clouds, and (d) higher than normal incidence of double ITCZ (Inter-tropical Convergence Zone). Even after several upgrades consisting of a sophisticated cloud-microphysics and sub-grid scale orographic precipitation into the Data Assimilation Office (DAO)'s atmospheric model (called GEOS-2 GCM) at two different resolutions, we found that the above deficiencies remained persistent. The two empirical solutions often used to counter the aforestated deficiencies consist of a) diffusion of moisture and heat within the lower troposphere to artificially force the shallow clouds; and b) arbitrarily invoke evaporation of in-cloud water for low-level clouds. Even though helpful, these implementations lack a strong physical rationale. Our research shows that two missing physical conditions can ameliorate the aforestated cloud-parameterization deficiencies. First, requiring an ascending cloud airmass to be saturated at its starting point will not only make the cloud instantly buoyant all through its ascent, but also provide the essential work function (buoyancy energy) that would promote more shallow clouds. Second, we argue that training clouds that are unstable to a finite vertical displacement, even if neutrally buoyant in their ambient environment, must continue to rise and entrain causing evaporation of in-cloud water. These concepts have not been invoked in any of the cloud

  20. Integrated Workforce Planning Model: A Proof of Concept

    NASA Technical Reports Server (NTRS)

    Guruvadoo, Eranna K.

    2001-01-01

    Recently, the Workforce and Diversity Management Office at KSC have launched a major initiative to develop and implement a competency/skill approach to Human Resource management. As the competency/skill dictionary is being elaborated, the need for a competency-based workforce-planning model is recognized. A proof of concept for such a model is presented using a multidimensional data model that can provide the data infrastructure necessary to drive intelligent decision support systems for workforce planing. The components of competency-driven workforce planning model are explained. The data model is presented and several schemes that would support the workforce-planning model are presented. Some directions and recommendations for future work are given.

  1. Limitations of the planning organ at risk volume (PRV) concept

    SciTech Connect

    Stroom, Joep C. . E-mail: j.stroom@nki.nl; Heijmen, Ben J.M.

    2006-09-01

    Purpose: Previously, we determined a planning target volume (PTV) margin recipe for geometrical errors in radiotherapy equal to M{sub T} = 2{sigma} + 0.7{sigma}, with {sigma} and {sigma} standard deviations describing systematic and random errors, respectively. In this paper, we investigated margins for organs at risk (OAR), yielding the so-called planning organ at risk volume (PRV). Methods and Materials: For critical organs with a maximum dose (D{sub max}) constraint, we calculated margins such that D{sub max} in the PRV is equal to the motion averaged D{sub max} in the (moving) clinical target volume (CTV). We studied margins for the spinal cord in 10 head-and-neck cases and 10 lung cases, each with two different clinical plans. For critical organs with a dose-volume constraint, we also investigated whether a margin recipe was feasible. Results: For the 20 spinal cords considered, the average margin recipe found was: M{sub R} = 1.6{sigma} + 0.2{sigma} with variations for systematic and random errors of 1.2{sigma} to 1.8{sigma} and -0.2{sigma} to 0.6{sigma}, respectively. The variations were due to differences in shape and position of the dose distributions with respect to the cords. The recipe also depended significantly on the volume definition of D{sub max}. For critical organs with a dose-volume constraint, the PRV concept appears even less useful because a margin around, e.g., the rectum changes the volume in such a manner that dose-volume constraints stop making sense. Conclusion: The concept of PRV for planning of radiotherapy is of limited use. Therefore, alternative ways should be developed to include geometric uncertainties of OARs in radiotherapy planning.

  2. Use Dose Bricks Concept to Implement Nasopharyngeal Carcinoma Treatment Planning

    PubMed Central

    Wu, Jia-Ming; Yu, Tsan-Jung; Yeh, Shyh-An; Chao, Pei-Ju; Huang, Chih-Jou

    2014-01-01

    Purpose. A “dose bricks” concept has been used to implement nasopharyngeal carcinoma treatment plan; this method specializes particularly in the case with bell shape nasopharyngeal carcinoma case. Materials and Methods. Five noncoplanar fields were used to accomplish the dose bricks technique treatment plan. These five fields include (a) right superior anterior oblique (RSAO), (b) left superior anterior oblique (LSAO), (c) right anterior oblique (RAO), (d) left anterior oblique (LAO), and (e) superior inferior vertex (SIV). Nondivergence collimator central axis planes were used to create different abutting field edge while normal organs were blocked by multileaf collimators in this technique. Results. The resulting 92% isodose curves encompassed the CTV, while maximum dose was about 115%. Approximately 50% volume of parotid glands obtained 10–15% of total dose and 50% volume of brain obtained less than 20% of total dose. Spinal cord receives only 5% from the scatter dose. Conclusions. Compared with IMRT, the expenditure of planning time and costing, “dose bricks” may after all be accepted as an optional implementation in nasopharyngeal carcinoma conformal treatment plan; furthermore, this method also fits the need of other nonhead and neck lesions if organ sparing and noncoplanar technique can be executed. PMID:24967395

  3. Core concepts of spatial prioritisation in systematic conservation planning.

    PubMed

    Kukkala, Aija S; Moilanen, Atte

    2013-05-01

    Systematic conservation planning (SCP) is a field of conservation biology concerned with delivering on-the-ground actions that achieve conservation goals. It describes a set of operational models that cover both design and implementation of conservation, with a strong focus on mobilising the collective action typically required to implement conservation. SCP, as it was originally described, was composed of six different stages: collection of data, identification of conservation goals, evaluation of the existing protected area network, design of expansions, implementation of conservation action, and long-term maintenance of biodiversity in the network. Since then, the operational model has been expanded into several different variants. Conservation actions applied inside SCP include establishment and expansion of reserve networks and allocation of habitat restoration and management. Within the broader context of SCP, there is a fundamental biogeographic-economic analysis frequently called spatial conservation prioritisation or conservation assessment, which is used for identifying where important areas for biodiversity are and how conservation goals might be achieved efficiently. Here, we review the usage and meaning of the 12 biogeographic-economic core concepts of SCP: adequacy, complementarity, comprehensiveness, effectiveness, efficiency, flexibility, irreplaceability, replacement cost, representation, representativeness, threat, and vulnerability. Some of the concepts have clear definitions whereas others may have alternative and possibly conflicting definitions. With a comprehensive literature review literature, we elucidate the historical backgrounds of these concepts, the first definitions and usages, alternative later definitions, key applications, and prior reviews. This review reduces linguistic uncertainty in the application of SCP. Since SCP is a global activity with a multitude of different stakeholders involved, it is vital that those involved can

  4. Core concepts of spatial prioritisation in systematic conservation planning

    PubMed Central

    Kukkala, Aija S; Moilanen, Atte

    2013-01-01

    Systematic conservation planning (SCP) is a field of conservation biology concerned with delivering on-the-ground actions that achieve conservation goals. It describes a set of operational models that cover both design and implementation of conservation, with a strong focus on mobilising the collective action typically required to implement conservation. SCP, as it was originally described, was composed of six different stages: collection of data, identification of conservation goals, evaluation of the existing protected area network, design of expansions, implementation of conservation action, and long-term maintenance of biodiversity in the network. Since then, the operational model has been expanded into several different variants. Conservation actions applied inside SCP include establishment and expansion of reserve networks and allocation of habitat restoration and management. Within the broader context of SCP, there is a fundamental biogeographic-economic analysis frequently called spatial conservation prioritisation or conservation assessment, which is used for identifying where important areas for biodiversity are and how conservation goals might be achieved efficiently. Here, we review the usage and meaning of the 12 biogeographic-economic core concepts of SCP: adequacy, complementarity, comprehensiveness, effectiveness, efficiency, flexibility, irreplaceability, replacement cost, representation, representativeness, threat, and vulnerability. Some of the concepts have clear definitions whereas others may have alternative and possibly conflicting definitions. With a comprehensive literature review literature, we elucidate the historical backgrounds of these concepts, the first definitions and usages, alternative later definitions, key applications, and prior reviews. This review reduces linguistic uncertainty in the application of SCP. Since SCP is a global activity with a multitude of different stakeholders involved, it is vital that those involved can

  5. Refining the Commission's Work Plan on Student Success: A Progress Report. Report 10-23

    ERIC Educational Resources Information Center

    Wilson, Stacy; Fuller, Ryan; Trott, Marcia

    2010-01-01

    Among its planning and coordinating responsibilities, the California Postsecondary Education Commission is required by state law to assess the ongoing effectiveness of postsecondary education in meeting societal, educational, and workforce needs. At its September 28-29 meeting, the Commission supported staff's proposed work plan to transition from…

  6. A packet-based concept for spacecraft command planning

    NASA Technical Reports Server (NTRS)

    Barnes, Valerie B.

    1993-01-01

    The current generation of spacecraft being developed and operated by the Applied Physics Laboratory provides users with access to a broad spectrum of scientific instruments on maneuverable platforms that can be oriented for observation of both moving and stationary targets of interest. The capability of these increasingly complex spacecraft to perform data collection operations is approaching one observation per orbit. To enable both rapid configuration and generation of complex spacecraft command sequences, as well as reusability of command sequences among data collection operations, a packet-based concept for spacecraft command planning has been developed. The configuration of the spacecraft for any operation is designed using 'packets' where a packet represents a set of commands that is reusable. The packets can be combined in varying levels of functionality, and in varying time relationships, to create an observation timeline. At the lowest packet level are primitives. Primitives relate the details of command generation for a particular spacecraft to a 'message template.' Thus the packet concept itself is reusable from one spacecraft to the next.

  7. Emergency response concept plan for Tooele Army Depot and vicinity

    SciTech Connect

    Carnes, S.A.; Sorensen, J.H.; Rogers, G.O.; Shumpert, B.L.; Miller, R.L.; Watson, A.P.; Chester, C.V.

    1989-10-01

    The continued storage and disposal of the United States' unitary chemical stockpile, including that portion stored at Tooele Army Depot (TEAD) near Tooele, Utah, have the potential for accidental releases that could escape installation boundaries and pose a threat to civilian populations. The US Army, in conjunction with the Federal Emergency Management Agency and other federal agencies, is committed to implement an emergency preparedness program that will significantly reduce the probability of adverse effects from such releases. This concept plan, which is but a part of a comprehensive ongoing effort, provides a framework for initiating such a program for the TEAD stockpile. This report develops information and methodologies that bear on two major decisions for such a program -- determining emergency planning zones and selecting protective action strategies. These decisions are based on the hazards posed by the TEAD stockpile and its disposal. These hazards, in turn, are based largely on the distribution of potential accidental releases associated with interim storage and disposal activities and associated external events (e.g., earthquakes and airplane crashes), the distribution of natural features that can affect an agent release (topographical features and meteorological characteristics), and the distribution of people and resources (e.g., homes, schools, and hospitals) potentially affected by an accidental release. 22 refs., 9 figs., 12 tabs.

  8. The Planning Unit Concept: An Alternative Approach to Program-Budgeting in Public Service Agencies.

    ERIC Educational Resources Information Center

    Weiss, Edmond; And Others

    The Planning Unit is a concept employed in resource requirements forecasting for the public service agencies, as an alternative to the conventional hierarchical program-structure used in PPB systems. The planning unit concept allows analysts to generate cost analyses by several simultaneous program-structures, not all of which need be in a…

  9. Implementation of contemporary radiation therapy planning concepts for pediatric Hodgkin lymphoma: Guidelines from the International Lymphoma Radiation Oncology Group.

    PubMed

    Hodgson, David C; Dieckmann, Karin; Terezakis, Stephanie; Constine, Louis

    2015-01-01

    The optimal management of children with Hodgkin lymphoma (HL) should limit the risk of treatment-related toxicity without compromising disease control. Consequently, increasing effort is being directed to retaining the demonstrated efficacy of radiation therapy (RT) in maximizing the cure of HL while reducing the radiation exposure of normal tissues. Historically, guidelines for RT volume definition used in pediatric HL trials have referenced 2-dimensional imaging and bony landmarks to define classical involved field RT. With recognition of the efficacy of chemotherapy, the data on the adverse late effects of radiation, and the evolution of advanced imaging techniques that reveal the location of both tumor and normal tissues, it is necessary that radiation techniques for children and adolescents be refined. The concepts described by the International Commission on Radiation Units provide a common approach for field definition using 3-dimensional computed tomographic--based RT planning and volumetric image guidance. Here we describe the application of these concepts in the planning of RT for pediatric HL. This will be increasingly important as current and upcoming pediatric HL trials will employ these concepts to deliver RT. PMID:25413415

  10. An allotment planning concept and related computer software for planning the fixed satellite service at the 1988 space WARC

    NASA Technical Reports Server (NTRS)

    Miller, Edward F.; Heyward, Ann O.; Ponchak, Denise S.; Spence, Rodney L.; Whyte, Wayne A., Jr.

    1987-01-01

    The authors describe a two-phase approach to allotment planning suitable for use in planning the fixed satellite service at the 1988 Space World Administrative radio Conference (ORB-88). The two phases are (1) the identification of predetermined geostationary arc segments common to groups of administrations and (2) the use of a synthesis program to identify example scenarios of space station placements. The planning approach is described in detail and is related to the objectives of the conference. Computer software has been developed to implement the concepts, and the logic and rationale for identifying predetermined arc segments is discussed. Example scenarios are evaluated to give guidance in the selection of the technical characteristics of space communications systems to be planned. The allotment planning concept described guarantees equitable access to the geostationary orbit, provides flexibility in implementation, and reduces the need for coordination among administrations.

  11. Control Concepts in Educational Planning. Bulletin No. 5.

    ERIC Educational Resources Information Center

    Francis, N. D.

    The educational system is characterized by a vector matrix differential equation, and it is shown that the concepts of modern control theory such as observability, controllability, and optimal control can give deeper insight into the behavior of the educational system. The identification of the system dynamics and the definition of a realistic…

  12. View planning and mesh refinement effects on a semi-automatic three-dimensional photorealistic texture mapping procedure

    NASA Astrophysics Data System (ADS)

    Shih, Chihhsiong; Yang, Yuanfan

    2012-02-01

    A novel three-dimensional (3-D) photorealistic texturing process is presented that applies a view-planning and view-sequencing algorithm to the 3-D coarse model to determine a set of best viewing angles for capturing the individual real-world objects/building's images. The best sequence of views will generate sets of visible edges in each view to serve as a guide for camera field shots by either manual adjustment or equipment alignment. The best view tries to cover as many objects/building surfaces as possible in one shot. This will lead to a smaller total number of shots taken for a complete model reconstruction requiring texturing with photo-realistic effects. The direct linear transformation method (DLT) is used for reprojection of 3-D model vertices onto a two-dimensional (2-D) images plane for actual texture mapping. Given this method, the actual camera orientations do not have to be unique and can be set arbitrarily without heavy and expensive positioning equipment. We also present results of a study on the texture-mapping precision as a function of the level of visible mesh subdivision. In addition, the control points selection for the DLT method used for reprojection of 3-D model vertices onto 2-D textured images is also investigated for its effects on mapping precision. By using DLT and perspective projection theories on a coarse model feature points, this technique will allow accurate 3-D texture mapping of refined model meshes of real-world buildings. The novel integration flow of this research not only greatly reduces the human labor and intensive equipment requirements of traditional methods, but also generates a more appealing photo-realistic appearance of reconstructed models, which is useful in many multimedia applications. The roles of view planning (VP) are multifold. VP can (1) reduce the repetitive texture-mapping computation load, (2) can present a set of visible model wireframe edges that can serve as a guide for images with sharp edges and

  13. New Concepts in Vocational-Technical Programs and Planning.

    ERIC Educational Resources Information Center

    Mochon, Clint

    The latest principle behind designing and planning vocational-technical school is "built-in-pride", which must be motivated in both student and surrounding community. We are at last emerging from the dark tunnel of the "trade school", away from the cold institutional look, the clamor of shop classrooms, echoing corridors, and the invisible tattoo…

  14. American History: The Multi-Concept Plan for High School.

    ERIC Educational Resources Information Center

    Nicolosi, Louis J.; And Others

    Providing a basic framework for a one year American history course for secondary students, this curriculum guide offers help for teachers in planning, organizing, and teaching social studies. Designed to cover the whole panorama of history (1450 through 1969) in sequence, the course aims to help students understand early events and how they are…

  15. New Concept in Architectural Planning for Schools of Dentistry.

    ERIC Educational Resources Information Center

    Myrick, Richard

    1965-01-01

    Analysis of the architectural requirements for schools of dentistry emphasizes conceptual categorization. Physical design needs are determined through procedures of primary functional analysis and operations research. Psychological needs, although less often considered in facility planning, are shown to be critical in terms of student, teacher,…

  16. Planning for Long-Term Care: Concept, Definition, and Measurement

    ERIC Educational Resources Information Center

    Friedemann, Marie-Luise; Newman, Frederick L.; Seff, Laura R.; Dunlop, Burton D.

    2004-01-01

    Purpose: This study explores the development and testing of an instrument to measure long-term-care planning behavior. Design and Methods: Researchers operationalized proposed constructs and response styles as statements in a questionnaire. A telephone survey involved 150 randomly selected residents of Miami-Dade County, Florida who were between…

  17. Re-analysis of narcotic critical body residue data using the equilibrium distribution concept and refined partition coefficients.

    PubMed

    Endo, Satoshi

    2016-08-10

    Narcosis occurs as a result of the accumulation of chemicals in the phospholipid membrane. The toxic threshold concentration in the membrane is thought to be relatively constant across different chemicals and species. Hence, estimating chemical concentrations in the membrane is expected to reduce the variability of narcotic critical body residue (CBR) data. In this study, a high quality CBR dataset for three aquatic species reported recently in the literature was evaluated with the internal equilibrium distribution concept. The raw wet-weight-based CBR values were converted to membrane-weight-based CBR values by assuming that the chemical is distributed in storage lipids, membranes, proteins, and water according to the respective equilibrium partition coefficients. Several sets of partition coefficients were compared for this analysis. The results were consistent with the notion that the use of a structural protein instead of serum albumin as a surrogate for the body protein fraction could reduce the variability of CBRs. Partition coefficients predicted by polyparameter linear free energy relationships (PP-LFERs) reduced the variability of CBRs as much as or even more than experimental partition coefficients did. It is suggested that CBR data for chemicals with larger structural diversity and biological species with more distinct compositions are needed to evaluate further the equilibrium distribution concept and the constant membrane threshold hypothesis. PMID:27136717

  18. An allotment planning concept and related computer software for planning the fixed satellite service at the 1988 space WARC

    NASA Technical Reports Server (NTRS)

    Miller, Edward F.; Heyward, Ann O.; Ponchak, Denise S.; Spence, Rodney L.; Whyte, Wayne A., Jr.; Zuzek, John E.

    1987-01-01

    Described is a two-phase approach to allotment planning suitable for use in establishing the fixed satellite service at the 1988 Space World Administrative Radio Conference (ORB-88). The two phases are (1) the identification of predetermined geostationary arc segments common togroups of administrations, and (2) the use of a synthesis program to identify example scenarios of space station placements. The planning approach is described in detail and is related to the objectives of the confernece. Computer software has been developed to implement the concepts, and a complete discussion on the logic and rationale for identifying predetermined arc segments is given. Example scenarios are evaluated to give guidance in the selection of the technical characteristics of space communications systems to be planned. The allotment planning concept described guarantees in practice equitable access to the geostationary orbit, provides flexibility in implementation, and reduces the need for coordination among administrations.

  19. An allotment planning concept and related computer software for planning the fixed satellite service at the 1988 space WARC

    NASA Astrophysics Data System (ADS)

    Miller, Edward F.; Heyward, Ann O.; Ponchak, Denise S.; Spence, Rodney L.; Whyte, Wayne A., Jr.; Zuzek, John E.

    1987-11-01

    Described is a two-phase approach to allotment planning suitable for use in establishing the fixed satellite service at the 1988 Space World Administrative Radio Conference (ORB-88). The two phases are (1) the identification of predetermined geostationary arc segments common togroups of administrations, and (2) the use of a synthesis program to identify example scenarios of space station placements. The planning approach is described in detail and is related to the objectives of the confernece. Computer software has been developed to implement the concepts, and a complete discussion on the logic and rationale for identifying predetermined arc segments is given. Example scenarios are evaluated to give guidance in the selection of the technical characteristics of space communications systems to be planned. The allotment planning concept described guarantees in practice equitable access to the geostationary orbit, provides flexibility in implementation, and reduces the need for coordination among administrations.

  20. A Case Study in Master Planning the Learning Landscape Hub Concepts for the University at Buffalo

    ERIC Educational Resources Information Center

    Dugdale, Shirley; Torino, Roger; Felix, Elliot

    2009-01-01

    This case study describes concepts for three types of learning spaces that grew out of a Learning Landscape planning process. The process was part of a master plan study for the three campuses of the University at Buffalo. It involved research into user needs and aspirations about future pedagogy, development of learning space strategy,…

  1. Simulation of flow in the Edwards Aquifer, San Antonio region, Texas, and refinement of storage and flow concepts

    USGS Publications Warehouse

    Maclay, R.W.; Land, L.F.

    1987-01-01

    The Edwards aquifer is a complexly faulted, carbonate aquifer lying within the Balcones fault zone of south-central Texas. The aquifer is recharged mainly by streamflow losses in the outcrop area of the Edwards aquifer and is discharged by major springs located at considerable distances, as much as 150 mi, from the areas of recharge, and by wells. Groundwater flow within the Edwards aquifer of the San Antonio region was simulated to investigate concepts relating to the storage and flow characteristics. A general purpose, finite difference model, modified to provide the capability of representing barrier faults, was used to simulate groundwater flow and storage in the aquifer. The simulations investigated the effects of complex geologic structures and significant changes in transmissivity, anisotropy, and storage coefficient, with initial values based on concepts developed in previous studies. Results of the simulations confirmed the original estimates of transmissivity values (> 100 sq ft/sec) in the confined zone of the aquifer between San Antonio and Comal Springs. A storage coefficient of 0.05 in the unconfined zone of the aquifer produced the best simulation of water levels and springflow. A major interpretation resulting from the simulations is that two essentially independent areas of regional flow were identified in the west and central part of the study area. Flow from the two areas converges at Comal Springs. The directions of computed flux vectors reflected the presence of major barrier faults which locally deflect patterns of groundwater movement. The most noticeable deflection is the convergence of flow through the geologic structural opening, the Knippa gap, in eastern Uvalde County. A second significant interpretation is that groundwater flow in northeastern Bexar, Comal, and Hays Counties is diverted by barrier faults toward San Marcos Springs, a regional discharge point. (Lantz-PTT)

  2. The 'People Plan' Concept for Contract Closure - 12432

    SciTech Connect

    Diaz, Peter

    2012-07-01

    The U.S. Department of Energy's (DOE) first-of-a-kind closure project at the Hanford Site in Richland, Washington, still has more than 3 years to run, but its contractor, Washington Closure Hanford (WCH), has already started its plans for going out of business. It will be the first contract that closes in increments and, paramount to its success, will be its ability to provide a disciplined and positive approach to release personnel while at the same time retaining personnel critical to timely and safe completion of the work scope. In May 2011, WCH produced the people plan, a program that maximizes communication and support for employees being released, provides an incentivization strategy to retain personnel to the end of their assignments, and reflects a sensitivity to the long-term goals of the contract and WCH's parent companies. The combination of all of these efforts equal one thing: treating employees with respect by providing specific information in a timely manner; respecting employees by sharing as much information as possible, as soon as possible, with as much detail as possible; and respecting each individual's ability to be in control of their next step in their life or career. The project is only in the second ORW and has 13 more before the end of the contract. That time remaining will continue to bring new challenges and unknowns, but the confidence and trust of the employees is proving to be solid. This is largely as a result of the stability provided by the people plan program. A success that can only truly be measured by the continued positive response it has already received from WCH's employees. (authors)

  3. Simulation of flow in the Edwards Aquifer, San Antonio region, Texas, and refinement of storage and flow concepts

    USGS Publications Warehouse

    Maclay, Robert W.; Land, Larry F.

    1988-01-01

    The Edwards aquifer is a complexly faulted, carbonate aquifer lying within the Balcones fault zone of south-central Texas. The aquifer consists of thin- to massive-bedded limestone and dolomite, most of which is in the form of mudstones and wackestones. Well-developed secondary porosity has formed in association with former erosional surfaces within the carbonate rocks, within dolomitized-burrowed tidal and evaporitic deposits, and along inclined fractures to produce an aquifer with transmissivities greater than 100 ft2/s. The aquifer is recharged mainly by streamflow losses in the outcrop area of the Edwards aquifer and is discharged by major springs located at considerable distances, as much as 150 mi, from the areas of recharge and by wells. Ground-water flow within the Edwards aquifer of the San Antonio region was simulated to investigate concepts relating to the storage and flow characteristics. The concepts of major interest were the effects of barrier faults on flow direction, water levels, springflow, and storage within the aquifer. A general-purpose, finite-difference model, modified to provide the capability of representing barrier faults, was used to simulate ground-water flow and storage in the aquifer. The approach in model development was to conduct a series of simulations beginning with a simple representation of the aquifer framework and then proceeding to subsequent representations of increasing complexity. The simulations investigated the effects of complex geologic structures and of significant changes in transmissivity, anisotropy, and storage coefficient. Initial values of transmissivity, anisotropy, and storage coefficient were estimated based on concepts developed in previous studies. Results of the simulations confirmed the original estimates of transmissivity values (greater than 100 square feet/s) in the confined zone of the aquifer between San Antonio and Comal Springs. A storage coefficient of 0.05 in the unconfined zone of the aquifer

  4. Student learning with concept mapping of care plans in community-based education.

    PubMed

    Hinck, Susan M; Webb, Patricia; Sims-Giddens, Susan; Helton, Caroline; Hope, Kathryn L; Utley, Rose; Savinske, Deborah; Fahey, Elizabeth M; Yarbrough, Sue

    2006-01-01

    Concept mapping, a learning strategy used to understand key concepts and relationships between concepts, has been suggested as a method to plan and evaluate nursing care. The purpose of this study was to empirically test the effectiveness of concept mapping for student learning and the students' satisfaction with the strategy. A quasi-experimental pre- and posttest design was used to examine the content of concept maps of care plans constructed by junior-level baccalaureate students (n = 23) at the beginning and end of a community-based mental health course. Additionally, students completed a questionnaire to self-evaluate their learning and report their satisfaction with concept mapping. Findings indicated that concept mapping significantly improved students' abilities to see patterns and relationships to plan and evaluate nursing care, and most students (21/23) expressed satisfaction in using the strategy. This study supported concept mapping as an additional learning strategy and has extended knowledge in community-based nursing education. PMID:16459286

  5. Manned orbital systems concepts study. Book 3: Configurations for extended duration missions. [mission planning and project planning for space missions

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Mission planning, systems analysis, and design concepts for the Space Shuttle/Spacelab system for extended manned operations are described. Topics discussed are: (1) payloads, (2) spacecraft docking, (3) structural design criteria, (4) life support systems, (5) power supplies, and (6) the role of man in long duration orbital operations. Also discussed are the assembling of large structures in space. Engineering drawings are included.

  6. Refining small intestinal bacterial overgrowth diagnosis by means of carbohydrate specificity: a proof-of-concept study

    PubMed Central

    Enko, Dietmar; Halwachs-Baumann, Gabriele; Stolba, Robert; Mangge, Harald; Kriegshäuser, Gernot

    2015-01-01

    Background: Diagnosis of small intestinal bacterial overgrowth (SIBO) remains challenging. This study aimed at proving the diagnostic concept of carbohydrate-specific SIBO (cs-SIBO) using glucose, fructose and sorbitol hydrogen (H2)/methane (CH4) breath testing (HMBT). Methods: In this study 125 patients referred to our outpatient clinic for SIBO testing were included. All individuals underwent glucose (50 g), fructose (25 g) and sorbitol (12.5 g) HMBT at 3 consecutive days. Patients with cs-SIBO (i.e. early H2/CH4 peak) were given rifaximin (600 mg/day) in a 10-day treatment. HMBT results were reassessed in a subset of patients 3–6 months after antibiotic therapy. In view of cs-SIBO diagnosis, agreements between HMBT results obtained for different sugars were calculated using Cohen’s kappa (κ) with 95% confidence intervals (CIs). Results: A total of 59 (47.2%) patients presented an early H2/CH4 peak with one or more sugars. Among these, 21 (16.8%), 10 (8.0%) and 7 (5.6%) individuals had a positive HMBT result with either glucose, fructose or sorbitol, respectively. Another 21 (16.8%) patients with a positive glucose HMBT result were also found positive with an early H2/CH4 peak obtained after ingestion of fructose and/or sorbitol. Fair agreement was observed between glucose and fructose (κ = 0.26, p = 0.0018) and between glucose and sorbitol (κ = 0.18, p = 0.0178) HMBT results. Slight agreement was observed between fructose and sorbitol (κ = 0.03, p = 0.6955) HMBT results only. Successful antibiotic therapy with rifaximin could be demonstrated in 26/30 (86.7%) of patients as indicated by normal HMBT results and symptom remission. Conclusions: Combined glucose, fructose and sorbitol HMBT has the potential to optimize cs-SIBO diagnosis. Furthermore, the majority of patients with cs-SIBO seem to benefit from rifaximin therapy regardless of its carbohydrate specificity. PMID:27134657

  7. Level 5: user refinement to aid the fusion process

    NASA Astrophysics Data System (ADS)

    Blasch, Erik P.; Plano, Susan

    2003-04-01

    The revised JDL Fusion model Level 4 process refinement covers a broad spectrum of actions such as sensor management and control. A limitation of Level 4 is the purpose of control - whether it be for user needs or system operation. Level 5, User Refinement, is a modification to the Revised JDL model that distinguishes between machine process refinement and user refinement. User refinement can either be human control actions or refinement of the user's cognitive model. In many cases, fusion research concentrates on the machine and does not take full advantage of the human as not only a qualified expert to refine the fusion process, but also as customer for whom the fusion system is designed. Without user refinement, sensor fusion is incomplete, inadequate, and the user neglects its worthiness. To capture user capabilities, we explore the concept of user refinement through decision and action based on situational leadership models. We develop a Fuse-Act Situational User Refinement (FASUR) model that details four refinement behaviors: Neglect, Consult, Rely, and Interact and five refinement functions: Planning, Organizing, Coordinating, Directing, and Controlling. Process refinement varies for different systems and different user information needs. By designing a fusion system with a specific user in mind, vis Level 5, a fusion architecture can meet user's information needs for varying situations, extend user sensing capabilities for action, and increase the human-machine interaction.

  8. Operations and Maintenance Concept Plan for the Immobilized High Level Waste (IHLW) Interim Storage Facility

    SciTech Connect

    JANIN, L.F.

    2000-08-30

    This O&M Concept looks at the future operations and maintenance of the IHLW/CSB interim storage facility. It defines the overall strategy, objectives, and functional requirements for the portion of the building to be utilized by Project W-464. The concept supports the tasks of safety basis planning, risk mitigation, alternative analysis, decision making, etc. and will be updated as required to support the evolving design.

  9. The Single Habitat Module Concept for Exploration - Mission Planning and Mass Estimates

    NASA Technical Reports Server (NTRS)

    Chambliss, Joe

    2013-01-01

    The Single Habitat Module (SHM) concept approach to the infrastructure and conduct of exploration missions combines many of the new promising technologies with a central concept of mission architectures that use a single habitat module for all phases of an exploration mission. Integrating mission elements near Earth and fully fueling them prior to departure of the vicinity of Earth provides the capability of using the single habitat both in transit to an exploration destination and while exploring the destination. The concept employs the capability to return the habitat and interplanetary propulsion system to Earth vicinity so that those elements can be reused on subsequent exploration missions. This paper provides a review of the SHM concept, the advantages it provides, trajectory assessments related to use of a high specific impulse space based propulsion system, advances in mission planning and new mass estimates.

  10. The Single Habitat Module Concept for Exploration - Mission Planning and Mass Estimates

    NASA Technical Reports Server (NTRS)

    Chambliss, Joe

    2012-01-01

    The Single Habitat Module (SHM) concept approach to the infrastructure and conduct of exploration missions combines many of the new promising technologies with a central concept of mission architectures that use a single habitat module for all phases of an exploration mission. Integrating mission elements near Earth and fully fueling them prior to departure of the vicinity of Earth provides the capability of using the single habitat both in transit to an exploration destination and while exploring the destination. The concept employs the capability to return the habitat and interplanetary propulsion system to Earth vicinity so that those elements can be reused on subsequent exploration missions. This paper provides a review of the SHM concept, the advantages it provides, trajectory assessments related to use of a high specific impulse space based propulsion system, advances in mission planning and new mass estimates.

  11. Exploiting Variations in Concept Map Morphology as a Lesson-Planning Tool for Trainee Teachers in Higher Education

    ERIC Educational Resources Information Center

    Kinchin, I. M.; Alias, M.

    2005-01-01

    Consideration of variations in the gross morphology of concept maps can be helpful in the context of lesson planning by promoting the consideration of the multiple perspectives held by students. The three basic concept map structures are described as having particular utility at different stages of the planning process: (a) chain-type maps…

  12. Applying Comprehensive Environmental Assessment to Research Planning for Multiwalled Carbon Nanotubes: Refinements to Inform Future Stakeholder Engagement

    EPA Science Inventory

    We previously described our collective judgment methods to engage expert stakeholders in the Comprehensive Environmental Assessment (CEA) workshop process applied to nano-TiO2 and nano-Ag research planning. We identified several lessons learned in engaging stakeholders to identif...

  13. Summary of US Fusion Program Planning Documents Relating to Innovative Confinement Concepts (1992-2005)

    NASA Astrophysics Data System (ADS)

    Woodruff, S.

    2007-06-01

    During the 1990's approximately 15 planning documents were produced by community consensus and by panels of experts. These documents lead to the restructuring of the Office of Fusion Energy (OFE). The OFE adopted joint goals of science and performance and opened a solicitation for Innovative Confinement Concept (ICC) experiments. This paper summarizes the documents that appeared during this time that relate to the ICCs.

  14. Higher Education Planning for a Strategic Goal with a Concept Mapping Process at a Small Private College

    ERIC Educational Resources Information Center

    Driscoll, Deborah P.

    2010-01-01

    Faculty, staff, and administrators at a small independent college determined that planning with a Concept Mapping process efficiently produced strategic thinking and action plans for the accomplishment of a strategic goal to expand experiential learning within the curriculum. One year into a new strategic plan, the college enjoyed enrollment…

  15. Rethinking gender planning: a critical discussion of the use of the concept of gender.

    PubMed

    Wieringa, S E

    1998-01-01

    The introduction of the concept of gender in planning circles has allowed gender planners and feminist social scientists to concentrate on social relations and power structures underlying women's subordination. Since then, the 'gender analysis in development' has gradually replaced the 'women in development' approach. This approach has been accepted by mainstream development sectors, and the price of acceptance has been the depoliticization and desexualizations of gender planning. This paper discusses the origins of the concept of gender and emphasizes its radical and comprehensive elements. It then reviews three textbooks of major theorists on gender and development issues--Kabeer¿s, Moser¿s, and Young¿s, criticizing more extensively the problematic areas in Moser's conceptualization of the distinction between practical and strategic gender needs. The concluding page presents some recommendations on how to avoid the problems previously identified. It was argued that by narrowing gender down to socioeconomic issues, gender analysis loses its critical edge, its political, symbolic and sexual content. Finally, it is suggested that feminism should be viewed as the driving force behind gender planning, and planning initiatives should aim at maximizing the transformative potential of any program or project. PMID:12179943

  16. Using concept mapping as a planning tool: Child welfare citizen review panels.

    PubMed

    Miller, J Jay; Jones, Blake

    2015-12-01

    Citizen Review Panels (CRPs) are groups of citizen volunteers authorized by U.S. federal law to examine state child welfare agencies. These groups inspect policies and practices related to child protection responsibilities and are tasked with making recommendations for systemic improvement. Despite the federal mandate for each state to develop a CRP and the potential of these groups to positively impact child welfare practices, there is a dearth in the literature related to CRPs. Consequently, planning and evaluation processes of these groups vary widely. This study reports on the use of concept mapping (CM) to outline a framework for planning and subsequently evaluating the CRP in one southeastern state. CM is a mixed-method research approach that uses multi-dimensional scaling and hierarchical cluster analyses to explore an area of study. Through these analyses, the method creates visual depictions of conceptual relationships between ideas. Data yielded a seven cluster concept map that CRP members (N=36) utilized for planning processes, and subsequently for developing an internal evaluation tool. Results from this study offer a unifying framework by which CRPs, and similar groups in other areas can utilize for planning and evaluation purposes. After a review of pertinent literature on CRPs, this article explicates CM processes utilized in this study, describes results, discusses lessons learned, and outlines apposite areas for future CRP research. PMID:26343491

  17. Yakima/Klickitat Production Project Preliminary Design Report, Appendix A: Refined Project Goals and Harvest Managment Plan : Experimental Design Plan : Genetic Risk Assessment.

    SciTech Connect

    Yakima Indian Nation; Pacific Northwest Laboratory; Washington Department of Fisheries

    1990-03-01

    The purpose of the project as stated by the Northwest Power Planning Council is 'to test the assumption that new artificial production in the Yakima and Klickitat subbasins can be used to increase harvest and enhance natural production while maintaining genetic resources.'

  18. Revolutionary Aerospace Systems Concepts - Planning for the Future of Technology Investments

    NASA Technical Reports Server (NTRS)

    Ferebee, Melvin J., Jr.; Breckenridge, Roger A.; Hall, John B., Jr.

    2002-01-01

    In January, 2000, the NASA Administrator gave the following directions to Langley: "We will create a new role for Langley as a leader for the assessment of revolutionary aerospace system concepts and architectures, and provide resources needed to assure technology breakthroughs will be there to support these advanced concepts. This is critical in determining how NASA can best invest its resources to enable future missions." The key objective of the RASC team is to look beyond current research and technology (R&T) programs and missions and evolutionary technology development approaches with a "top-down" perspective to explore possible new mission capabilities. The accomplishment of this objective will allow NASA to provide the ability to go anywhere, anytime - safely, and affordably- to meet its strategic goals for exploration, science, and commercialization. The RASC Team will seek to maximize the cross-Enterprise benefits of these revolutionary capabilities as it defines the revolutionary enabling technology areas and performance levels needed. The product of the RASC Team studies will be revolutionary systems concepts along with enabling technologies and payoffs in new mission capabilities, which these concepts can provide. These results will be delivered to the NASA Enterprises and the NASA Chief Technologist for use in planning revolutionary future NASA R&T program investments.

  19. Enroute flight planning: Evaluating design concepts for the development of cooperative problem-solving systems

    NASA Technical Reports Server (NTRS)

    Smith, Philip J.

    1995-01-01

    There are many problem-solving tasks that are too complex to fully automate given the current state of technology. Nevertheless, significant improvements in overall system performance could result from the introduction of well-designed computer aids. We have been studying the development of cognitive tools for one such problem-solving task, enroute flight path planning for commercial airlines. Our goal has been two-fold. First, we have been developing specific system designs to help with this important practical problem. Second, we have been using this context to explore general design concepts to guide in the development of cooperative problem-solving systems. These design concepts are described below, along with illustrations of their application.

  20. CONTRASTING CONCEPTS IN CAMPUS PLANNING. SELECTED PAPERS FROM THE FIRST ANNUAL CONFERENCE, SOCIETY FOR COLLEGE AND UNIVERSITY PLANNING (PORTLAND STATE COLLEGE, PORTLAND, OREGON, AUGUST 13-14, 1966.)

    ERIC Educational Resources Information Center

    MAYER, FREDERICK W.

    THE PAPERS SUMMARIZED IN THIS DOCUMENT WERE GIVEN AT A S.C.U.P. CONFERENCE AND WERE BASED UPON EXPERIENCES AT COLLEGES IN SANTA CRUZ, CALIFORNIA, CHICAGO, ILLINOIS, AND PORTLAND, OREGON. CENTRAL TO ALL THE CONCEPTS OF PLANNING WAS THE LOCATION OF THE INSTITUTION, WITH THE ENSUING GEOPOLITICAL RESTRICTIONS. OTHER PLANNING CONSIDERATIONS VARIED IN…

  1. Front end evaluation research results. Communications and concept planning: Hatfield Marine Science Center

    NASA Technical Reports Server (NTRS)

    Falk, John H.; Holland, Dana

    1994-01-01

    An evaluation for the renovation of the existing visitor center at the Hatfield Marine Sciences Center (HMSC) was undertaken, in conjunction with the communications planning phase of the project. The outcome is expected to be the development of a communications plan and selection of concepts for visitors' interpretive experience. In the course of the evaluation, data were collected from 140 visitors to HMSC using both a questionnaire and face to face semi-structured interviews. Major results of the evaluation covered: 1, reasons for attending the HMSC; 2, visitor expectations; 3, visitors's knowledge of general science and of marine life and environments; 4, visitors' level of interest and attitudes toward exhibit themes; 5, issue areas of greatest interest; and 6, research areas of greatest interest.Visitors to t he HMSC had a strong orientation toward seeing and closely interacting with marine life and environments.

  2. Concepts, requirements, and design approaches for building successful planning and scheduling systems

    NASA Technical Reports Server (NTRS)

    Hornstein, Rhoda Shaller; Willoughby, John K.

    1991-01-01

    Traditional practice of systems engineering management assumes requirements can be precisely determined and unambiguously defined prior to system design and implementation; practice further assumes requirements are held static during implementation. Human-computer decision support systems for service planning and scheduling applications do not conform well to these assumptions. Adaptation to the traditional practice of systems engineering management are required. Basic technology exists to support these adaptations. Additional innovations must be encouraged and nutured. Continued partnership between the programmatic and technical perspective assures proper balance of the impossible with the possible. Past problems have the following origins: not recognizing the unusual and perverse nature of the requirements for planning and scheduling; not recognizing the best starting point assumptions for the design; not understanding the type of system that being built; and not understanding the design consequences of the operations concept selected.

  3. Breast cancer therapy planning - a novel support concept for a sequential decision making problem.

    PubMed

    Scherrer, Alexander; Schwidde, Ilka; Dinges, Andreas; Rüdiger, Patrick; Kümmel, Sherko; Küfer, Karl-Heinz

    2015-09-01

    Breast cancer is the most common carcinosis with the largest number of mortalities in women. Its therapy comprises a wide spectrum of different treatment modalities a breast oncologist decides about for the individual patient case. These decisions happen according to medical guide lines, current scientific publications and experiences acquired in former cases. Clinical decision making therefore involves the time-consuming search for possible therapy options and their thorough testing for applicability to the current patient case.This research work addresses breast cancer therapy planning as a multi-criteria sequential decision making problem. The approach is based on a data model for patient cases with therapy descriptions and a mathematical notion for therapeutic relevance of medical information. This formulation allows for a novel decision support concept, which targets at eliminating observed weaknesses in clinical routine of breast cancer therapy planning. PMID:25315184

  4. Site-specific emergency response concept plans for the Chemical Stockpile Disposal Program

    SciTech Connect

    Carnes, S.A.

    1989-12-01

    Site-specific emergency response concept plans were developed to help initiate enhanced emergency preparedness for continued storage of the stockpile and the Chemical Stockpile Disposal Program (CSDP) at the eight army installations storing the unitary chemical stockpile -- Aberdeen Proving Ground, Anniston Army Depot, Lexington-Blue Grass Army Depot, Newport Army Ammunition Plant, Pine Bluff Arsenal, Pueblo Depot Activity, Tooele Army Depot, and Umatilla Depot Activity. This document summarizes the emergency response plans for all the sites and highlights similarities and differences among them. Section 2 summarizes site-specific differences in stockpile hazard and risk by showing differences in planning-basis accident categories and distributions of topographical features, meteorological conditions, and populations at risk. Section 3 presents a summary of the methodology used to identify the emergency planning zones for each site and the actual recommended boundaries of those zones for the eight sites. Section 4 identifies feasible and recommended protective actions for the sites and explains reasons for differences in them. Finally, Section 5 notes the dependence of protective action effectiveness on the development and implementation of command and control and warning systems that can be implemented in a timely manner, it also identifies the differences in recommended lead times (i.e., from the onset of an accidental release) needed at the sites for effective implementation of protective actions. 17 refs., 11 figs. , 12 tabs.

  5. Mission planning and scheduling concept for the Advanced X-ray Astrophysics Facility (AXAF)

    NASA Technical Reports Server (NTRS)

    Newhouse, M.; Guffin, O. T.

    1994-01-01

    Projected for launch in the latter part of 1998, the Advanced X-ray Astrophysics Facility (AXAF), the third satellite in the Great Observatory series, promises to dramatically open the x-ray sky as the Hubble and Compton observatories have done in their respective realms. Unlike its companions, however, AXAF will be placed in a high altitude, highly elliptical orbit (10,000 x 100,000 km), and will therefore be subject to its own unique environment, spacecraft and science instrument constraints and communication network interactions. In support of this mission, ground operations personnel have embarked on the development of the AXAF Offline System (OFLS), a body of software divided into four basic functional elements: (1) Mission Planning and Scheduling, (2) Command Management, (3) Altitude Determination and Sensor Calibration and (4) Spacecraft Support and Engineering Analysis. This paper presents an overview concept for one of these major elements, the Mission Planning and Scheduling subsystem (MPS). The derivation of this concept is described in terms of requirements driven by spacecraft and science instrument characteristics, orbital environment and ground system capabilities. The flowdown of these requirements through the systems analysis process and the definition of MPS interfaces has resulted in the modular grouping of functional subelements depicted in the design implementation approach. The rationale for this design solution is explained and capabilities for the initial prototype system are proposed from the user perspective.

  6. Library Spaces for 21st-Century Learners: A Planning Guide for Creating New School Library Concepts

    ERIC Educational Resources Information Center

    Sullivan, Margaret

    2013-01-01

    "Library Spaces for 21st-Century Learners: A Planning Guide for Creating New School Library Concepts" focuses on planning contemporary school library spaces with user-based design strategies. The book walks school librarians and administrators through the process of gathering information from students and other stakeholders involved in…

  7. Successful Proof of Concept of Family Planning and Immunization Integration in Liberia

    PubMed Central

    Cooper, Chelsea M; Fields, Rebecca; Mazzeo, Corinne I; Taylor, Nyapu; Pfitzer, Anne; Momolu, Mary; Jabbeh-Howe, Cuallau

    2015-01-01

    ABSTRACT Globally, unmet need for postpartum family planning remains high, while immunization services are among the most wide-reaching and equitable interventions. Given overlapping time frames, integrating these services provides an opportunity to leverage existing health visits to offer women more comprehensive services. From March through November 2012, Liberia's government, with support from the Maternal and Child Health Integrated Program (MCHIP), piloted an integrated family planning and immunization model at 10 health facilities in Bong and Lofa counties. Vaccinators provided mothers bringing infants for routine immunization with targeted family planning and immunization messages and same-day referrals to co-located family planning services. In February 2013, we compared service statistics for family planning and immunization during the pilot against the previous year's statistics. We also conducted in-depth interviews with service providers and other personnel and focus group discussions with clients. Results showed that referral acceptance across the facilities varied from 10% to 45% per month, on average. Over 80% of referral acceptors completed the family planning visit that day, of whom over 90% accepted a contraceptive method that day. The total number of new contraceptive users at participating facilities increased by 73% in Bong and by 90% in Lofa. Women referred from immunization who accepted family planning that day accounted for 44% and 34% of total new contraceptive users in Bong and Lofa, respectively. In Lofa, pilot sites administered 35% more Penta 1 and 21% more Penta 3 doses during the pilot period compared with the same period of the previous year, while Penta 1 and Penta 3 administration decreased in non-pilot facilities. In Bong, there was little difference in the number of Penta 1 and Penta 3 doses administered between pilot and non-pilot facilities. In both counties, Penta 1 to Penta 3 dropout rates increased at pilot sites but not in

  8. Successful proof of concept of family planning and immunization integration in Liberia.

    PubMed

    Cooper, Chelsea M; Fields, Rebecca; Mazzeo, Corinne I; Taylor, Nyapu; Pfitzer, Anne; Momolu, Mary; Jabbeh-Howe, Cuallau

    2015-03-01

    Globally, unmet need for postpartum family planning remains high, while immunization services are among the most wide-reaching and equitable interventions. Given overlapping time frames, integrating these services provides an opportunity to leverage existing health visits to offer women more comprehensive services. From March through November 2012, Liberia's government, with support from the Maternal and Child Health Integrated Program (MCHIP), piloted an integrated family planning and immunization model at 10 health facilities in Bong and Lofa counties. Vaccinators provided mothers bringing infants for routine immunization with targeted family planning and immunization messages and same-day referrals to co-located family planning services. In February 2013, we compared service statistics for family planning and immunization during the pilot against the previous year's statistics. We also conducted in-depth interviews with service providers and other personnel and focus group discussions with clients. Results showed that referral acceptance across the facilities varied from 10% to 45% per month, on average. Over 80% of referral acceptors completed the family planning visit that day, of whom over 90% accepted a contraceptive method that day. The total number of new contraceptive users at participating facilities increased by 73% in Bong and by 90% in Lofa. Women referred from immunization who accepted family planning that day accounted for 44% and 34% of total new contraceptive users in Bong and Lofa, respectively. In Lofa, pilot sites administered 35% more Penta 1 and 21% more Penta 3 doses during the pilot period compared with the same period of the previous year, while Penta 1 and Penta 3 administration decreased in non-pilot facilities. In Bong, there was little difference in the number of Penta 1 and Penta 3 doses administered between pilot and non-pilot facilities. In both counties, Penta 1 to Penta 3 dropout rates increased at pilot sites but not in non

  9. Ubiquitous geospatial concept in evolution of the macro and micro spatial planning

    NASA Astrophysics Data System (ADS)

    Sabri, S.; Ludin, A. N. M.; Majid, M. R.

    2014-02-01

    There are many examples of GIS application in planning such as urban land-use planning, cultural heritage conservation, coastal zone management, and the design of structure plans for sustainable economic development. All these applications are dealing with systems in which natural and human factors are interconnected. But an issue that should be addressed is to what extent the current information technology is able to connect all these parts together? Contemporary improvement in information technology made the computer so imbedded in our everyday practices that we use it without having to think about it. Thus, computing is becoming truly ubiquitous and is available anywhere anytime. Advances in the internet facilities and devices, such as high speed wireless networks, mobile middleware, and smart technologies, has pushed the concept of ubiquitous computing to the forefront of GIS research and development. There are developments in this regards, these are such as GeoWeb 2.0, voluntarily geographic Information (VGI), and Mashups, whereby the application of cloud computing was possible in visualizing urban air pollution and emergency responses to ensure the safety and security. These advancements therefore, have changed the conventional facet of macro and micro spatial planning. Every possible information system such as residential, medical, business, environmental, governmental, and the like can be linked through ubiquitous computing technologies and acts as a virtually one system which works for society. However, the journey to achieve a true ubiquitous GIS is not without challenges. Despite the current potentials there are many issues and obstacles need to be addressed before GIS can to be truly ubiquitous in planning context. Perhaps four criteria as explained by Goodchild et al (1997) can be applied to ubiquitous GIS in planning very well: the system must be distributed (data storage, processing and user interaction can occur at locations that are potentially

  10. Whole Brain Irradiation With Hippocampal Sparing and Dose Escalation on Multiple Brain Metastases: A Planning Study on Treatment Concepts

    SciTech Connect

    Prokic, Vesna; Wiedenmann, Nicole; Fels, Franziska; Schmucker, Marianne; Nieder, Carsten; Grosu, Anca-Ligia

    2013-01-01

    Purpose: To develop a new treatment planning strategy in patients with multiple brain metastases. The goal was to perform whole brain irradiation (WBI) with hippocampal sparing and dose escalation on multiple brain metastases. Two treatment concepts were investigated: simultaneously integrated boost (SIB) and WBI followed by stereotactic fractionated radiation therapy sequential concept (SC). Methods and Materials: Treatment plans for both concepts were calculated for 10 patients with 2-8 brain metastases using volumetric modulated arc therapy. In the SIB concept, the prescribed dose was 30 Gy in 12 fractions to the whole brain and 51 Gy in 12 fractions to individual brain metastases. In the SC concept, the prescription was 30 Gy in 12 fractions to the whole brain followed by 18 Gy in 2 fractions to brain metastases. All plans were optimized for dose coverage of whole brain and lesions, simultaneously minimizing dose to the hippocampus. The treatment plans were evaluated on target coverage, homogeneity, and minimal dose to the hippocampus and organs at risk. Results: The SIB concept enabled more successful sparing of the hippocampus; the mean dose to the hippocampus was 7.55 {+-} 0.62 Gy and 6.29 {+-} 0.62 Gy, respectively, when 5-mm and 10-mm avoidance regions around the hippocampus were used, normalized to 2-Gy fractions. In the SC concept, the mean dose to hippocampus was 9.8 {+-} 1.75 Gy. The mean dose to the whole brain (excluding metastases) was 33.2 {+-} 0.7 Gy and 32.7 {+-} 0.96 Gy, respectively, in the SIB concept, for 5-mm and 10-mm hippocampus avoidance regions, and 37.23 {+-} 1.42 Gy in SC. Conclusions: Both concepts, SIB and SC, were able to achieve adequate whole brain coverage and radiosurgery-equivalent dose distributions to individual brain metastases. The SIB technique achieved better sparing of the hippocampus, especially when a10-mm hippocampal avoidance region was used.

  11. The role of the concept of biologically effective dose (BED) in treatment planning in radiosurgery.

    PubMed

    Millar, William T; Hopewell, John W; Paddick, Ian; Lindquist, Christer; Nordströn, Håkan; Lidberg, Pär; Gårding, Jonas

    2015-09-01

    Radiosurgery (RS) treatment times vary, even for the same prescription dose, due to variations in the collimator size, the number of iso-centres/beams/arcs used and the time gap between each of these exposures. The biologically effective dose (BED) concept, incorporating fast and slow components of repair, was used to show the likely influence of these variables for Gamma Knife patients with Vestibular Schwannomas. Two patients plans were selected, treated with the Model B Gamma Knife, these representing the widest range of treatment variables; iso-centre numbers 3 and 13, overall treatment times 25.4 and 129.6 min, prescription dose 14 Gy. These were compared with 3 cases treated with the Perfexion(®) Gamma Knife. The iso-centre number varied between 11 and 18, treatment time 35.7 - 74.4 min, prescription dose 13 Gy. In the longer Model B Gamma Knife treatment plan the 14 Gy iso-dose was best matched by the 58 Gy2.47 iso-BED line, although higher and lower BED values were associated with regions on the prescription iso-dose. The equivalent value for the shorter treatment was 85 Gy2.47. BED volume histograms showed that a BED of 85 Gy2.47 only covered ∼65% of the target in the plan with the longer overall treatment time. The corresponding BED values for the 3 cases, treated with the Perfexion(®) Gamma Knife, were 59.5, 68.5 and 71.5 Gy2.47. In conclusion BED calculations, taking account of the repair of sublethal damage, may indicate the importance of reporting overall time to reflect the biological effectiveness of the total physical dose applied. PMID:25982304

  12. Confocal microscopy refines generic concept of a problematic taxon: rediagnosis of the genus Neoprothrix and remarks on female anatomy of eriophyoids (Acari: Eriophyoidea).

    PubMed

    Chetverikov, Philipp E; Desnitskiy, Alexey G; Navia, Denise

    2015-01-01

    Due to the higher resolution, confocal microscopy (CLSM) can be applied to refine the origin of tiny structures of the autofluorescent exoskeletons of microarthropods (mites in particular) which are hard to visualize using traditional differential interference contract light microscopy (DIC LM) and phase contrast light microscopy (PC LM). Three-dimensional (3D) reconstructions of the prodorsal shield topography of eriophyoid mites using Neoprothrix hibiscus Reis and Navia as a model, suggest that the structures originally treated as paired setae vi are two internal rod-like apodemes. Based on this, the genus Neoprothrix is excluded from the subfamily Prothricinae Amrine and transferred to the subfamily Sierraphytoptinae Keifer. Observations on partially cleared specimens of N. hibiscus showed that remnants of the central nervous system, paired glands and developing oocytes can be visualized using DIC LM and CLSM methods. New high quality microscope images are provided of recently described "flower-shaped" structures and two main components of yolk inclusions of the mature eggs inside the oviduct. PMID:25781123

  13. A Title I Refinement: Alaska.

    ERIC Educational Resources Information Center

    Hazelton, Alexander E.; And Others

    Through joint planning with a number of school districts and the Region X Title I Technical Assistance Center, and with the help of a Title I Refinement grant, Alaska has developed a system of data storage and retrieval using microcomputers that assists small school districts in the evaluation and reporting of their Title I programs. Although this…

  14. National cyber defense high performance computing and analysis : concepts, planning and roadmap.

    SciTech Connect

    Hamlet, Jason R.; Keliiaa, Curtis M.

    2010-09-01

    There is a national cyber dilemma that threatens the very fabric of government, commercial and private use operations worldwide. Much is written about 'what' the problem is, and though the basis for this paper is an assessment of the problem space, we target the 'how' solution space of the wide-area national information infrastructure through the advancement of science, technology, evaluation and analysis with actionable results intended to produce a more secure national information infrastructure and a comprehensive national cyber defense capability. This cybersecurity High Performance Computing (HPC) analysis concepts, planning and roadmap activity was conducted as an assessment of cybersecurity analysis as a fertile area of research and investment for high value cybersecurity wide-area solutions. This report and a related SAND2010-4765 Assessment of Current Cybersecurity Practices in the Public Domain: Cyber Indications and Warnings Domain report are intended to provoke discussion throughout a broad audience about developing a cohesive HPC centric solution to wide-area cybersecurity problems.

  15. New Concepts in Planning and Funding Athletic, Physical Education, and Recreational Facilities.

    ERIC Educational Resources Information Center

    Bronzan, Robert T.

    The major purpose of this book is to provide information needed to plan, design, equip, and finance a sports-related facility. Planning and financing are discussed and guidelines offered for securing and compiling data for analysis in justifying new facilities. Other chapters discuss determining facility needs and eventual plans, selection of the…

  16. From Concept to Commissioning: Planning, Design, and Construction of Campus Facilities.

    ERIC Educational Resources Information Center

    Guckert, Donald, Ed.

    To address the growing interest in campus planning, design, and construction projects, this anthology compiles articles previously published in "Facilities Manager." The beginning chapters focus on campus architecture, master planning, and project planning. The mid-section of the book offers information on the critical issues of time management,…

  17. Short Lesson Plan Associated with Increased Acceptance of Evolutionary Theory and Potential Change in Three Alternate Conceptions of Macroevolution in Undergraduate Students

    ERIC Educational Resources Information Center

    Abraham, Joel K.; Perez, Kathryn E.; Downey, Nicholas; Herron, Jon C.; Meir, Eli

    2012-01-01

    Undergraduates commonly harbor alternate conceptions about evolutionary biology; these alternate conceptions often persist, even after intensive instruction, and may influence acceptance of evolution. We interviewed undergraduates to explore their alternate conceptions about macroevolutionary patterns and designed a 2-h lesson plan to present…

  18. Refines Efficiency Improvement

    SciTech Connect

    WRI

    2002-05-15

    Refinery processes that convert heavy oils to lighter distillate fuels require heating for distillation, hydrogen addition or carbon rejection (coking). Efficiency is limited by the formation of insoluble carbon-rich coke deposits. Heat exchangers and other refinery units must be shut down for mechanical coke removal, resulting in a significant loss of output and revenue. When a residuum is heated above the temperature at which pyrolysis occurs (340 C, 650 F), there is typically an induction period before coke formation begins (Magaril and Aksenova 1968, Wiehe 1993). To avoid fouling, refiners often stop heating a residuum before coke formation begins, using arbitrary criteria. In many cases, this heating is stopped sooner than need be, resulting in less than maximum product yield. Western Research Institute (WRI) has developed innovative Coking Index concepts (patent pending) which can be used for process control by refiners to heat residua to the threshold, but not beyond the point at which coke formation begins when petroleum residua materials are heated at pyrolysis temperatures (Schabron et al. 2001). The development of this universal predictor solves a long standing problem in petroleum refining. These Coking Indexes have great potential value in improving the efficiency of distillation processes. The Coking Indexes were found to apply to residua in a universal manner, and the theoretical basis for the indexes has been established (Schabron et al. 2001a, 2001b, 2001c). For the first time, a few simple measurements indicates how close undesired coke formation is on the coke formation induction time line. The Coking Indexes can lead to new process controls that can improve refinery distillation efficiency by several percentage points. Petroleum residua consist of an ordered continuum of solvated polar materials usually referred to as asphaltenes dispersed in a lower polarity solvent phase held together by intermediate polarity materials usually referred to as

  19. Curriculum Planning and the Concept of Participation in the Reggio Emilia Pedagogical Approach

    ERIC Educational Resources Information Center

    Hocevar, Andreja; Šebart, Mojca Kovac; Štefanc, Damijan

    2013-01-01

    The article analyses two defining assumptions about the Reggio Emilia (RE) approach: the absence of a planned curriculum designed in advance as a basis for educational work and children's participation in preschools. The authors demonstrate that different approaches to planning preschool education have advantages and disadvantages, which we…

  20. Developing an Institutional Knowledge Bank at Ohio State University: From Concept to Action Plan.

    ERIC Educational Resources Information Center

    Rogers, Sally A.

    2003-01-01

    There is a growing interest among academic institutions in collecting, preserving, and creating value-added services from digital content produced in teaching and research. Ohio State University plans to build on existing initiatives to create an institutional repository called the Knowledge Bank. An implementation plan and cost assessment are in…

  1. Educational Planning and Management in Small States: Concepts and Experiences. Challenge of Scale Series.

    ERIC Educational Resources Information Center

    Baldacchino, Godfrey, Ed.; Farrugia, Charles J., Ed.

    This collection of papers presents the critical reflections on the management and planning of education of 18 senior officials working in 12 small island nations. The papers are a result of their participation in the Postgraduate Diploma in Educational Planning and Management in Small States program at the University of Malta. The book is divided…

  2. Six Basic Plan Concepts Used for California School Housing. A Sequential Development from 1900 to Today.

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento. Bureau of School Planning.

    A floor plan accompanies each of six chronologically arranged schemes for housing educational programs. Scheme A represents the in-line corridor plan whose main characteristics are--(1) double loaded corridors with fixed bearing walls, (2) single window walls providing minimal light and ventilation, and (3) small classrooms with fixed desks and…

  3. Satellite Power System (SPS) concept development and evaluation program plan, July 1977 - August 1980

    NASA Technical Reports Server (NTRS)

    1978-01-01

    An overview of the program to evaluate the solar satellite power system concept is presented. Environmental, health, and safety factors are examined along with economic, international, and institutional issues.

  4. Satellite power systems (SPS) concept definition study. Volume 7: SPS program plan and economic analysis, appendixes

    NASA Technical Reports Server (NTRS)

    Hanley, G.

    1978-01-01

    Three appendixes in support of Volume 7 are contained in this document. The three appendixes are: (1) Satellite Power System Work Breakdown Structure Dictionary; (2) SPS cost Estimating Relationships; and (3) Financial and Operational Concept. Other volumes of the final report that provide additional detail are: Executive Summary; SPS Systems Requirements; SPS Concept Evolution; SPS Point Design Definition; Transportation and Operations Analysis; and SPS Technology Requirements and Verification.

  5. Planned updates and refinements to the Central Valley hydrologic model with an emphasis on improving the simulation of land subsidence in the San Joaquin Valley

    USGS Publications Warehouse

    Faunt, Claudia C.; Hanson, Randall T.; Martin, Peter; Schmid, Wolfgang

    2011-01-01

    California's Central Valley has been one of the most productive agricultural regions in the world for more than 50 years. To better understand the groundwater availability in the valley, the U.S. Geological Survey (USGS) developed the Central Valley hydrologic model (CVHM). Because of recent water-level declines and renewed subsidence, the CVHM is being updated to better simulate the geohydrologic system. The CVHM updates and refinements can be grouped into two general categories: (1) model code changes and (2) data updates. The CVHM updates and refinements will require that the model be recalibrated. The updated CVHM will provide a detailed transient analysis of changes in groundwater availability and flow paths in relation to climatic variability, urbanization, stream flow, and changes in irrigated agricultural practices and crops. The updated CVHM is particularly focused on more accurately simulating the locations and magnitudes of land subsidence. The intent of the updated CVHM is to help scientists better understand the availability and sustainability of water resources and the interaction of groundwater levels with land subsidence.

  6. Recovery from a chemical weapons accident or incident: A concept paper on planning

    SciTech Connect

    Herzenberg, C.L.; Haffenden, R.; Lerner, K.; Meleski, S.A.; Tanzman, E.A.; Lewis, L.M.; Hemphill, R.C.; Adams, J.D.

    1994-04-01

    Emergency planning for an unintended release of chemical agent from the nation`s chemical weapons stockpile should include preparation for. the period following implementation of immediate emergency response. That period -- the recovery, reentry, and restoration stage -- is the subject of this report. The report provides an overview of the role of recovery, reentry, and restoration planning in the Chemical Stockpile Emergency Preparedness Program (CSEPP), describes the transition from immediate emergency response to restoration, and analyzes the legal framework that would govern restoration activities. Social, economic, and administrative issues, as well as technical ones, need to be considered in the planning effort. Because of possible jurisdictional conflicts, appropriate federal, state, and local agencies need to be included in a coordinated planning process. Advance consideration should be given to the pertinent federal and state statutes and regulations. On the federal level, the principal statutes and regulations to be considered are those associated with the Comprehensive Environmental Response, Compensation, and Liability Act; the Resource Conservation and Recovery Act; and the National Environmental Policy Act. This report recommends that extensive preaccident planning be undertaken for the recovery, reentry, and restoration stage and outlines several key issues that should be considered in that planning. The need for interagency cooperation and coordination at all levels of the planning process is emphasized.

  7. Personalized Medicine: how to Switch from the Concept to the Integration into the Clinical Development Plan to Obtain Marketing Authorization.

    PubMed

    Becquemont, Laurent; Bordet, Régis; Cellier, Dominic

    2012-01-01

    One of the challenges of the coming years is to personalize medicine in order to provide each patient with an individualized treatment plan. The three objectives of personalized medicine are to refine diagnosis, rationalize treatment and engage patients in a preventive approach. Personalization can be characterized by various descriptors whether related to the field, biology, imaging, type of lesion of the entity to be treated, comorbidity factors, coprescriptions or the environment As part of personalized medicine focused on biological markers including genetics or genomics, the integration of the clinical development plan to obtain marketing authorization may be segmented in 3 stages with a known descriptor identified before clinical development, a known descriptor discovered during clinical development or a known descriptor known after clinical development. For each stage, it is important to clearly define the technical optimization elements, to specify the expectations and objectives, to examine the methodological aspects of each clinical development phase and finally to consider the fast changing regulatory requirements in view of the few registered therapeutics complying with the definition of personalized medicine as well as the significant technological breakthroughs according to the screened and selected biomarkers. These considerations should be integrated in view of the time required for clinical development from early phase to MA, i.e. more than 10 years. Moreover, business models related to the economic environment should be taken into account when deciding whether or not to retain a biomarker allowing the selection of target populations in a general population. PMID:23110835

  8. Capricious Cables: Understanding the Key Concepts in Transmission Expansion Planning and Its Models

    SciTech Connect

    Donohoo, P.; Milligan, M.

    2014-06-01

    The extra-high-voltage transmission network is the bulk transport network of the electric power system. To understand how the future power system may react to planning decisions today, wide-area transmission models are increasingly used to aid decision makers and stakeholders. The goal of this work is to illuminate these models for a broader audience that may include policy makers or relative newcomers to the field of transmission planning. This paper explains the basic transmission expansion planning model formulation. It highlights six of the major simplifications made in transmission expansion planning models and the resulting need to contextualize model results using knowledge from other models and knowledge not captured in the modeling process.

  9. The Single Habitat Module Concept for Exploration - Mission Planning and Mass Estimates

    NASA Technical Reports Server (NTRS)

    Chambliss, Joe; Studak, J. W.

    2013-01-01

    The Single Habitat Module (SHM) concept approach to the infrastructure and conduct of exploration missions combines many new promising technologies with a central concept of mission architectures that use a single habitat module for all phases of an exploration mission. Integrating mission elements near Earth and fully fueling them prior to departure of the vicinity of Earth provides the capability of using the single habitat both in transit to/from an exploration destination and while exploring the destination. The concept employs the capability to return the habitat and interplanetary propulsion system to Earth vicinity so that those elements can be reused on subsequent exploration missions. This paper provides an overview of the SHM concept and the advantages it provides. The paper also provides a summary of calculations of the mass of the Habitat Propulsion System (HPS) needed to get the habitat from low-Mars orbit (LMO) to the surface and back to LMO, and an overview of trajectory and mission mass assessments related to use of a high specific impulse space-based propulsion system. Those calculations led to the conclusion that the SHM concept results in low total mass required and streamlines mission operations to explore Mars (or other exploration destinations).

  10. The Single Habitat Module Concept for Exploration - Mission Planning and Mass Estimates

    NASA Technical Reports Server (NTRS)

    Chambliss, Joe; Studak, J. W.

    2013-01-01

    The Single Habitat Module (SHM) concept approach to the infrastructure and conduct of exploration missions combines many of new promising technologies with a central concept of mission architectures that use a single habitat module for all phases of an exploration mission. Integrating mission elements near Earth and fully fueling them prior to departure of the vicinity of Earth provides the capability of using the single habitat both in transit to/from an exploration destination and while exploring the destination. The concept employs the capability to return the habitat and interplanetary propulsion system to Earth vicinity so that those elements can be reused on subsequent exploration missions. This paper provides an overview of the SHM concept and the advantages it provides. A summary of calculations of the mass of the habitat propulsion system (HPS) needed to get the habitat from Low Mars Orbit (LMO) to the surface and back to LMO and an overview of trajectory and mission mass assessments related to use of a high specific impulse space based propulsion system is provided. Those calculations lead to the conclusion that the SHM concept can significantly reduce the mass required and streamline mission operations to explore Mars (and thus all exploration destinations).

  11. Preservice Teachers' Exploration of Children's Alternative Conceptions: Cornerstone for Planning to Teach Science

    NASA Astrophysics Data System (ADS)

    Pringle, Rose M.

    2006-09-01

    Investigation involving children’s understandings of scientific concepts have been a dominant area of research in science education over the last 2 1/2 decades. One fruitful outcome of these studies is to alert teachers to difficulties in learning science. Although this information is commendable in highlighting their existence, not much is presented on how to deal with the alternative conceptions. It is generally believed that teachers tend to teach the way they were taught, and breaking this cycle requires different emphasis on pedagogy in teacher education. The focus of this article is on preservice teachers’ experiences in a science education course as they explore the importance of children’s alternative conceptions and in using such knowledge to make decisions about teaching.

  12. Large Deployable Reflector (LDR) system concept and technology definition study. Volume 2: Technology assessment and technology development plan

    NASA Technical Reports Server (NTRS)

    Agnew, Donald L.; Jones, Peter A.

    1989-01-01

    A study was conducted to define reasonable and representative LDR system concepts for the purpose of defining a technology development program aimed at providing the requisite technological capability necessary to start LDR development by the end of 1991. This volume presents thirteen technology assessments and technology development plans, as well as an overview and summary of the LDR concepts. Twenty-two proposed augmentation projects are described (selected from more than 30 candidates). The five LDR technology areas most in need of supplementary support are: cryogenic cooling; astronaut assembly of the optically precise LDR in space; active segmented primary mirror; dynamic structural control; and primary mirror contamination control. Three broad, time-phased, five-year programs were synthesized from the 22 projects, scheduled, and funding requirements estimated.

  13. Satellite Power Systems (SPS) concept definition study. Volume 7: SPS program plan and economic analysis

    NASA Technical Reports Server (NTRS)

    Hanley, G.

    1978-01-01

    The economic and programmatic requirements for a recommended SPS solar photovoltaic baseline concept were analyzed. Costs are determined for the DDT&E; initial capital investment (covers initial procurement and emplacement of each SPS plant and equipment); replacement capital investment (capital asset replacement over the SPS operating life); operations and maintenance (expendables, minor maintenance, repair crews); and taxes/insurance.

  14. Using the Force Concept Inventory To Monitor Student Learning and to Plan Teaching.

    ERIC Educational Resources Information Center

    Savinainen, Antti; Scott, Philip

    2002-01-01

    The Force Concept Inventory (FCI) is a multiple-choice test designed to monitor students' understanding of force and related kinematics. Outlines how the FCI was used to evaluate student learning following a newly developed approach to teaching mechanics in a Finnish upper secondary school. Offers an example of the benefits that can follow from…

  15. Refining of metallurgical-grade silicon

    NASA Technical Reports Server (NTRS)

    Dietl, J.

    1986-01-01

    A basic requirement of large scale solar cell fabrication is to provide low cost base material. Unconventional refining of metallurical grade silicon represents one of the most promising ways of silicon meltstock processing. The refining concept is based on an optimized combination of metallurgical treatments. Commercially available crude silicon, in this sequence, requires a first pyrometallurgical step by slagging, or, alternatively, solvent extraction by aluminum. After grinding and leaching, high purity qualtiy is gained as an advanced stage of refinement. To reach solar grade quality a final pyrometallurgical step is needed: liquid-gas extraction.

  16. Setting objectives for community and systems change: an application of concept mapping for planning a statewide health improvement initiative.

    PubMed

    Trochim, William M K; Milstein, Bobby; Wood, Betty J; Jackson, Susan; Pressler, Virginia

    2004-01-01

    The Hawaii Department of Health (HDOH) used concept mapping techniques to engage local stakeholders and national subject area experts in defining the community and system factors that affect individuals' behaviors related to tobacco, nutrition, and physical activity. Over eight working days, project participants brainstormed 496 statements (edited to a final set of 90), which were then sorted and rated for their importance and feasibility. A sequence of multivariate statistical analyses, including multidimensional scaling and hierarchical cluster analysis, generated maps and figures that were then interpreted by project stakeholders. The results were immediately incorporated into an official plan, approved by the governor and state legislature, recommending how Hawaii's tobacco settlement resources could be used to create sustainable changes in population health. The results also provide empirical support for the premise that both community and systems factors ought to be considered when planning comprehensive health improvement initiatives. PMID:14965431

  17. Solvent refining process

    SciTech Connect

    Mead, T.C.; Sequeira, A.J.; Smith, B.F.

    1981-10-13

    An improved process is described for solvent refining lubricating oil base stocks from petroleum fractions containing both aromatic and nonaromatic constituents. The process utilizes n-methyl-2-pyrrolidone as a selective solvent for aromatic hydrocarbons wherein the refined oil fraction and the extract fraction are freed of final traces of solvent by stripping with gaseous ammonia. The process has several advantages over conventional processes including a savings in energy required for the solvent refining process, and reduced corrosion of the process equipment.

  18. Using the Concept of "Population Dose" in Planning and Evaluating Community-Level Obesity Prevention Initiatives

    ERIC Educational Resources Information Center

    Cheadle, Allen; Schwartz, Pamela M.; Rauzon, Suzanne; Bourcier, Emily; Senter, Sandra; Spring, Rebecca; Beery, William L.

    2013-01-01

    When planning and evaluating community-level initiatives focused on policy and environment change, it is useful to have estimates of the impact on behavioral outcomes of particular strategies (e.g., building a new walking trail to promote physical activity). We have created a measure of estimated strategy-level impact--"population dose"--based on…

  19. Parametric Rietveld refinement

    PubMed Central

    Stinton, Graham W.; Evans, John S. O.

    2007-01-01

    In this paper the method of parametric Rietveld refinement is described, in which an ensemble of diffraction data collected as a function of time, temperature, pressure or any other variable are fitted to a single evolving structural model. Parametric refinement offers a number of potential benefits over independent or sequential analysis. It can lead to higher precision of refined parameters, offers the possibility of applying physically realistic models during data analysis, allows the refinement of ‘non-crystallographic’ quantities such as temperature or rate constants directly from diffraction data, and can help avoid false minima. PMID:19461841

  20. [Oncologic after-care--a patient-oriented concept. Basic diagnostic plan for pediatric oncology patients].

    PubMed

    Duffner, U; Sauter, S; Bergsträsser, E; Brandis, M; Niemeyer, C

    1995-01-01

    With intensive treatment many children and young adults with cancer can be cured of their disease. Therefore, the recognition of late effects of therapy will become increasingly important. Future concepts of follow-up care in pediatric oncology will have to serve two purposes: First, to determine the status of the malignant disease with early diagnosis of relapse and second, to recognize relevant side effects of treatment. We present a comprehensive approach of follow-up care which is primarily based on the definition of risk criteria for the development of relevant organ toxicity after different treatment modalities. For each patient a standardized summary of therapy delivered is documented. According to the definition of the risk criteria an individualized schedule for follow-up is decided upon. We hope that this structured concept will result in appropriate patient care while keeping the diagnostic efforts and costs limited. PMID:7564151

  1. Planned neck dissection for patients with complete response to chemoradiotherapy: a concept approaching obsolescence.

    PubMed

    Ferlito, Alfio; Corry, June; Silver, Carl E; Shaha, Ashok R; Thomas Robbins, K; Rinaldo, Alessandra

    2010-02-01

    The question of efficacy of "planned" neck dissection following complete response to chemoradiation of head and neck cancer is discussed. There is general agreement that preemptive neck dissection in patients who present initially with low volume (N1) neck disease is not necessary. However, routine performance of planned neck dissection for patients who present initially with high volume (> or =N2) disease remains controversial. The authors reviewed a large number of studies reported in the recent literature and discuss how they affect this debate.Twenty-four of the reviewed studies indicate a benefit in regional control obtained by "planned" neck dissection among patients who had bulky neck disease pretreatment. All these studies are retrospective, they do not assess treatment response prior to surgery, although they do show very good regional control rates. Twenty-six studies demonstrate no benefit from "planned" neck dissection after complete clinical response. The reasons for these different conclusions include the development of more effective chemoradiation regimens which have improved the initial locoregional control rates of patients undergoing primary chemoradiation treatment, and improvements in diagnostic technology which have increased ability to detect low volume persistent tumor in the post treatment period. When neck dissection is necessary for persistent or recurrent disease, recent studies have shown that selective or superselective neck dissection may produce results therapeutically equivalent to those obtained with more extensive procedures, with less morbidity.There is now a large body of evidence, based on long-term clinical outcomes, that patients who have achieved a complete clinical (including radiologic) response to chemoradiation have a low rate of isolated neck failure, and the continued use of planned neck dissection for these patients cannot be justified. PMID:19572281

  2. Project plan for joint FAA/NASA head-up display concept evaluation

    NASA Technical Reports Server (NTRS)

    Haines, R. F.

    1978-01-01

    Head-Up Display (HUD) concept for large commercial turbojet transport aircraft is considered for the its contribution to aviation safety in the form of improved performance during the approach and landing phase flight. The basic reearch areas represent fundamental questions that are still unresolved and which were considered important to the effective use of the HUD by pilots. Project documentation and management responsibilities are outlined.

  3. Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 5: Nuclear electric propulsion vehicle

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The nuclear electric propulsion (NEP) concept design developed in support of the Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) study is presented. The evolution of the NEP concept is described along with the requirements, guidelines, and assumptions for the design. Operating modes and options are defined and a systems description of the vehicle is presented. Artificial gravity configuration options and space and ground support systems are discussed. Finally, an implementation plan is presented which addresses technology needs, schedules, facilities and costs.

  4. Dose refinement. ARAC's role

    SciTech Connect

    Ellis, J. S.; Sullivan, T. J.; Baskett, R. L.

    1998-06-01

    The Atmospheric Release Advisory Capability (ARAC), located at the Lawrence Livermore National Laboratory, since the late 1970's has been involved in assessing consequences from nuclear and other hazardous material releases into the atmosphere. ARAC's primary role has been emergency response. However, after the emergency phase, there is still a significant role for dispersion modeling. This work usually involves refining the source term and, hence, the dose to the populations affected as additional information becomes available in the form of source term estimates release rates, mix of material, and release geometry and any measurements from passage of the plume and deposition on the ground. Many of the ARAC responses have been documented elsewhere. 1 Some of the more notable radiological releases that ARAC has participated in the post-emergency phase have been the 1979 Three Mile Island nuclear power plant (NPP) accident outside Harrisburg, PA, the 1986 Chernobyl NPP accident in the Ukraine, and the 1996 Japan Tokai nuclear processing plant explosion. ARAC has also done post-emergency phase analyses for the 1978 Russian satellite COSMOS 954 reentry and subsequent partial burn up of its on board nuclear reactor depositing radioactive materials on the ground in Canada, the 1986 uranium hexafluoride spill in Gore, OK, the 1993 Russian Tomsk-7 nuclear waste tank explosion, and lesser releases of mostly tritium. In addition, ARAC has performed a key role in the contingency planning for possible accidental releases during the launch of spacecraft with radioisotope thermoelectric generators (RTGs) on board (i.e. Galileo, Ulysses, Mars-Pathfinder, and Cassini), and routinely exercises with the Federal Radiological Monitoring and Assessment Center (FRMAC) in preparation for offsite consequences of radiological releases from NPPs and nuclear weapon accidents or incidents. Several accident post-emergency phase assessments are discussed in this paper in order to illustrate

  5. Using the Force Concept Inventory to monitor student learning and to plan teaching

    NASA Astrophysics Data System (ADS)

    Savinainen, Antti; Scott, Philip

    2002-01-01

    This is the second of two papers focusing on the Force Concept Inventory, a multiple-choice test designed to monitor students' understanding of force and related kinematics. In this paper we outline how the FCI was used to evaluate student learning following a newly developed approach to teaching mechanics in a Finnish upper secondary school. We believe that this case offers a compelling example of the benefits (in terms of enhanced student learning) that can follow from research- or evidence-based approaches to teaching.

  6. Airspace Systems Program: Next Generation Air Transportation System Concepts and Technology Development FY2010 Project Plan Version 3.0

    NASA Technical Reports Server (NTRS)

    Kopardekar, Parimal H.

    2010-01-01

    This document describes the FY2010 plan for the management and execution of the Next Generation Air Transportation System (NextGen) Concepts and Technology Development (CTD) Project. The document was developed in response to guidance from the Airspace Systems Program (ASP), as approved by the Associate Administrator of the Aeronautics Research Mission Directorate (ARMD), and from guidelines in the Airspace Systems Program Plan. Congress established the multi-agency Joint Planning and Development Office (JPDO) in 2003 to develop a vision for the 2025 Next Generation Air Transportation System (NextGen) and to define the research required to enable it. NASA is one of seven agency partners contributing to the effort. Accordingly, NASA's ARMD realigned the Airspace Systems Program in 2007 to "directly address the fundamental research needs of the Next Generation Air Transportation System...in partnership with the member agencies of the JPDO." The Program subsequently established two new projects to meet this objective: the NextGen-Airspace Project and the NextGen-Airportal Project. Together, the projects will also focus NASA s technical expertise and world-class facilities to address the question of where, when, how and the extent to which automation can be applied to moving aircraft safely and efficiently through the NAS and technologies that address optimal allocation of ground and air technologies necessary for NextGen. Additionally, the roles and responsibilities of humans and automation influence in the NAS will be addressed by both projects. Foundational concept and technology research and development begun under the NextGen-Airspace and NextGen-Airportal projects will continue. There will be no change in NASA Research Announcement (NRA) strategy, nor will there be any change to NASA interfaces with the JPDO, Federal Aviation Administration (FAA), Research Transition Teams (RTTs), or other stakeholders

  7. LST: The National Space Observatory concept - An observatory for future astronomer involvement in planning and use

    NASA Technical Reports Server (NTRS)

    Roman, N. G.

    1974-01-01

    The Large Space Telescope (LST) will be a unique facility which must be designed to serve the needs of all potential users throughout the world. This requires that a representative group of astronomers work intimately with the engineers in the early design of the telescope and that astronomers continue to be closely involved in the planning throughout the life of the project. Forty scientists are now defining the auxiliary instruments and their operation. Later, others will build instruments and participate in assigning observing time on the telescope, on the basis of the scientific merit of the proposed observation.

  8. Trajectory planning method for reduced patient risk in image-guided neurosurgery: concept and preliminary results

    NASA Astrophysics Data System (ADS)

    Shamir, Reuben R.; Joskowicz, Leo; Antiga, Luca; Foroni, Roberto I.; Shoshan, Yigal

    2010-02-01

    We present a new preoperative planning method to quantify and help reduce the risk associated with needle and tool insertion trajectories in image-guided keyhole neurosurgery. The goal is to quantify the risk of a proposed straight trajectory, and/or to find the trajectory with the lowest risk to nearby brain structures based on pre-operative CT/MRI images. The method automatically computes the risk associated with a given trajectory, or finds the trajectory with the lowest risk to nearby brain structures based on preoperative image segmentation and on a risk volume map. The surgeon can revise the suggested trajectory, add a new one using interactive 3D visualization, and obtain a quantitative risk measure. The trajectory risk is evaluated based on the tool placement uncertainty, on the proximity of critical brain structures, and on a predefined table of quantitative geometric risk measures. Our preliminary results on a clinical dataset with eight targets show a significant reduction in trajectory risk and a shortening of the preoperative planning time as compared to the conventional method.

  9. Remedial measures plan for a spill of solvent refined coal liquid at the SRC pilot plant, Ft. Lewis, Washington. Final Report

    SciTech Connect

    Grimshaw, T.W.; Little, W.M.

    1980-08-22

    On December 19, 1979, a spill of SRC liquid occurred during transfer of the liquid from a storage tank to sample drums. Approximately 2,300 gallons of fluid flowed into the floor of the tank farm and infiltrated into the porous and permeable gravels at the site. Because of concern for the possible impact of the SRC fluid on the quality of ground water, surface water, and water supply sources at and near the site, GMRC commissioned Radian to evaluate the problem and recommend specific measures to mitigate any known or anticipated impacts. This report presents the results of Radian's investigations. Although ground-water contamination apparently has occurred as a result of the December 19 spill, the contamination plume is localized to the vicinity of the SRC plant and Lake Sequalitchew. A contamination plume apparently is presently moving toward Lake Sequalitchew, but the two pump wells included in the Remedial Measures Plan will arrest this movement. These wells will be pumped until phenol concentrations in the groundwater fall to acceptable levels. The source of contamination at the spill is being cut off by excavation of the contaminated soil and sealing of the floor of the tank farm. No public water supplies are appreciably endangered by the December 19 spill. A long-term ground-water monitoring plan is being implemented to ensure early discovery of any unanticipated impacts of the spill. If further water quality problems are disclosed, additional remedial measures will be undertaken as necessary.

  10. Mission to Mars: Plans and concepts for the first manned landing

    NASA Astrophysics Data System (ADS)

    Oberg, J. E.

    The manned exploration and settlement of Mars is discussed. The topics considered include: the rationale for a manned landing; spaceships and propulsion for getting to Mars; human factors such as psychological stress, the effects of prolonged weightlessness, and radiation dangers; the return from Mars; site selection and relevant criteria; scientific problems that can be studied by landing men on Mars. Also addressed are economic resources of air and water on Mars and their relevance for transportation and mission planning; the exploration and utilization of Phobos and Deimos; cost factors; the possibilities of the Russians' going to Mars; political and social issues; colonies on Mars; and manipulation of the Martian environment to make it more habitable.

  11. The quality of family planning programs: concepts, measurements, interventions, and effects.

    PubMed

    RamaRao, Saumya; Mohanam, Raji

    2003-12-01

    This study reviews the major research and interventions concerning readiness and quality of care in family planning programs. It has three aims: to identify and describe the principal methodological research including conceptual frameworks, perspectives, and tools for measuring and improving quality; to describe the results from various intervention studies; and to assess what is known about the effect of such interventions. The review suggests that interventions that improve client-provider interactions show the greatest promise. Good quality of care results in such positive outcomes as clients' satisfaction, increased knowledge, and more effective and longer use of contraceptives. Rigorously documented evidence of the effects of interventions is sorely needed. The review indicates areas requiring additional research. PMID:14758606

  12. Concepts and Plans towards fast large scale Monte Carlo production for the ATLAS Experiment

    NASA Astrophysics Data System (ADS)

    Ritsch, E.; Atlas Collaboration

    2014-06-01

    The huge success of the physics program of the ATLAS experiment at the Large Hadron Collider (LHC) during Run 1 relies upon a great number of simulated Monte Carlo events. This Monte Carlo production takes the biggest part of the computing resources being in use by ATLAS as of now. In this document we describe the plans to overcome the computing resource limitations for large scale Monte Carlo production in the ATLAS Experiment for Run 2, and beyond. A number of fast detector simulation, digitization and reconstruction techniques are being discussed, based upon a new flexible detector simulation framework. To optimally benefit from these developments, a redesigned ATLAS MC production chain is presented at the end of this document.

  13. Dual solvent refining process

    SciTech Connect

    Woodle, R.A.

    1982-04-20

    A dual solvent refining process is claimed for solvent refining petroleum based lubricating oil stocks with n-methyl-2-pyrrolidone as selective solvent for aromatic oils wherein a highly paraffinic oil having a narrow boiling range approximating the boiling point of n-methyl-2-pyrrolidone is employed as a backwash solvent. The process of the invention results in an increased yield of refined lubricating oil stock of a predetermined quality and simplifies separation of the solvents from the extract and raffinate oil fractions.

  14. Unravelling the concept of consumer preference: implications for health policy and optimal planning in primary care.

    PubMed

    Foster, Michele M; Earl, Peter E; Haines, Terry P; Mitchell, Geoffrey K

    2010-10-01

    Accounting for consumer preference in health policy and delivery system design makes good economic sense since this is linked to outcomes, quality of care and cost control. Probability trade-off methods are commonly used in policy evaluation, marketing and economics. Increasingly applied to health matters, the trade-off preference model has indicated that consumers of health care discriminate between different attributes of care. However, the complexities of the health decision-making environment raise questions about the inherent assumptions concerning choice and decision-making behavior which frame this view of consumer preference. In this article, we use the example of primary care in Australia as a vehicle to examine the concept of 'consumer preference' from different perspectives within economics and discuss the significance of how we model preferences for health policy makers. In doing so, we question whether mainstream thinking, namely that consumers are capable of deliberating between rival strategies and are willing to make trade-offs, is a reliable way of thinking about preferences given the complexities of the health decision-making environment. Alternative perspectives on preference can assist health policy makers and health providers by generating more precise information about the important attributes of care that are likely to enhance consumer engagement and optimise acceptability of health care. PMID:20466449

  15. The NASA VLBI2010 Proof-of-Concept Demonstration and Future Plans

    NASA Technical Reports Server (NTRS)

    Niell, Arthur

    2010-01-01

    The next generation geodetic VLBI instrument is being developed with a goal of 1 mm position uncertainty in twenty-four hours. We have implemented a proof-of-concept system for a possible VLBI2010 signal chain, from feed through recorder, on the Westford (Massachusetts, USA) 18-m and MV-3 (Maryland, USA) 5-m antennas. Data have been obtained in four 512 MHz bands spanning the range 3.5 to 11 GHz to investigate the sensitivity and phase delay capability of the system. Using a new phase cal design, the phases have been aligned across four bands spanning 2 GHz with an RMS deviation of approximately eight degrees. Several components of the system will be improved for the prototype version of VLBI2010, including the feed, digital backend, and recorder, and these will be installed on a 12-m antenna that has been purchased and is ready for installation at the Goddard Space Flight Center outside of Washington, D.C., USA, site of the MV-3 antenna.

  16. Remedial measures plan for a spill of solvent refined coal liquid at the SRC Pilot Plant, Ft. Lewis, Washington. Final report

    SciTech Connect

    Grimshaw, T.W.; Little, W.M.

    1980-08-22

    On 19 December 1979, a spill of SRC liquid occurred during transfer of the liquid from a storage tank to sample drums. Approximately 2300 gallons of fluid flowed into the floor of the tank farm and infiltrated into the porous and permeable gravels at the site. Because of concern for the possible impact of the SRC fluid on the quality of ground water, surface water, and water supply sources at and near the site, GMRC commissioned Radian to evaluate the problem and recommend specific measures to mitigate any known or anticipated impacts. This report presents the results of Radian's investigations. Although ground-water contamination apparently has occurred as a result of the 19 December spill, the contamination plume is localized to the vicinity of the SRC plant and Lake Sequalitchew. A contamination plume apparently is presently moving toward Lake Sequalitchew, but the two pump wells included in the Remedial Mesures Plan will arrest this movement. These wells will be pumped until phenol concentrations in the groundwater fall to acceptable levels. The source of contamination at the spill is being cut off by excavation of the contaminated soil and sealing of the floor of the tank farm. No public water supplies are appreciably endangered by the 19 December spill. Most public wells are upgradient from the spill and are thus in no danger. The downgradient wells are protected by the fact that they tap deeper aquifers than the upper aquifer at the SRC plant site and by the buffering effect of Lake Sequalitchew. The upper aquifer in the vicinity of the spill site probably should not be considered for use as a public or private water supply for the foreseeable future.

  17. Short Lesson Plan Associated with Increased Acceptance of Evolutionary Theory and Potential Change in Three Alternate Conceptions of Macroevolution in Undergraduate Students

    PubMed Central

    Abraham, Joel K.; Perez, Kathryn E.; Downey, Nicholas; Herron, Jon C.; Meir, Eli

    2012-01-01

    Undergraduates commonly harbor alternate conceptions about evolutionary biology; these alternate conceptions often persist, even after intensive instruction, and may influence acceptance of evolution. We interviewed undergraduates to explore their alternate conceptions about macroevolutionary patterns and designed a 2-h lesson plan to present evidence that life has evolved. We identified three alternate conceptions during our interviews: that newly derived traits would be more widespread in extant species than would be ancestral traits, that evolution proceeds solely by anagenesis, and that lineages must become more complex over time. We also attempted to measure changes in the alternate conceptions and levels of acceptance of evolutionary theory in biology majors and nonmajors after exposure to the lesson plan. The instrument used to assess understanding had flaws, but our results are suggestive of mixed effects: we found a reduction in the first alternate conception, no change in the second, and reinforcement of the third. We found a small, but significant, increase in undergraduate acceptance of evolutionary theory in two trials of the lesson plan (Cohen's d effect sizes of 0.51 and 0.19). These mixed results offer guidance on how to improve the lesson and show the potential of instructional approaches for influencing acceptance of evolution. PMID:22665588

  18. Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 3: Nuclear thermal rocket vehicle

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This document presents the nuclear thermal rocket (NTR) concept design developed in support of the Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) study. The evolution of the NTR concept is described along with the requirements, guidelines and assumptions for the design. Operating modes and options are defined and a systems description of the vehicle is presented. Artificial gravity configuration options and space and ground support systems are discussed. Finally, an implementation plan is presented which addresses technology needs, schedules, facilities and costs.

  19. Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 4: Solar electric propulsion vehicle

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This document presents the solar electric propulsion (SEP) concept design developed as part of the Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) study. The evolution of the SEP concept is described along with the requirements, guidelines and assumptions for the design. Operating modes and options are defined and a systems description of the vehicle is presented. Artificial gravity configuration options and space and ground support systems are discussed. Finally, an implementation plan is presented which addresses technology needs, schedules, facilities, and costs.

  20. Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 2: Cryo/aerobrake vehicle

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The cryogenic/aerobrake (CAB) and the cryogenic all-propulsive (CAP) concept designs developed in support of the Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) study are presented. The evolution of the CAB and CAP concepts is described along with the requirements, guidelines and assumptions for the designs. Operating modes and options are defined and systems descriptions of the vehicles are presented. Artificial gravity configuration options and space and ground support systems are discussed. Finally, an implementation plan is presented which addresses technology needs, schedules, facilities, and costs.

  1. Definitions and Basic Concepts of Supply and Demand Analysis Used to Determine Market Equilibrium. Principles of Economics II (Microeconomics), Lesson Plan No. 6.

    ERIC Educational Resources Information Center

    Chiu-Irion, Vicky

    Developed as part of a 37.5-hour microeconomics course, this lesson plan focuses on the concepts of supply and demand analysis used to determine market equilibrium. The objectives of the 50-minute lesson are to enable the student to: (1) explain how a demand schedule is derived from raw data; (2) graph a demand curve from the demand schedule; (3)…

  2. ThermoData Engine (TDE): software implementation of the dynamic data evaluation concept. 5. Experiment planning and product design.

    PubMed

    Diky, Vladimir; Chirico, Robert D; Kazakov, Andrei F; Muzny, Chris D; Magee, Joseph W; Abdulagatov, Ilmutdin; Kang, Jeong Won; Kroenlein, Kenneth; Frenkel, Michael

    2011-01-24

    ThermoData Engine (TDE) is the first full-scale software implementation of the dynamic data evaluation concept, as reported recently in this journal. In the present paper, we describe development of an algorithmic approach to assist experiment planning through assessment of the existing body of knowledge, including availability of experimental thermophysical property data, variable ranges studied, associated uncertainties, state of prediction methods, and parameters for deployment of prediction methods and how these parameters can be obtained using targeted measurements, etc., and, indeed, how the intended measurement may address the underlying scientific or engineering problem under consideration. A second new feature described here is the application of the software capabilities for aid in the design of chemical products through identification of chemical systems possessing desired values of thermophysical properties within defined ranges of tolerance. The algorithms and their software implementation to achieve this are described. Finally, implementation of a new data validation and weighting system is described for vapor-liquid equilibrium (VLE) data, and directions for future enhancements are outlined. PMID:21166466

  3. REFINE WETLAND REGULATORY PROGRAM

    EPA Science Inventory

    The Tribes will work toward refining a regulatory program by taking a draft wetland conservation code with permitting incorporated to TEB for review. Progress will then proceed in developing a permit tracking system that will track both Tribal and fee land sites within reservati...

  4. Refining of Polysulfide Pulps

    NASA Astrophysics Data System (ADS)

    Copur, Yalcin

    This study compares the modified kraft process, polysulfide pulping, one of the methods to obtain higher pulp yield, with conventional kraft method. More specifically, the study focuses on the refining effects of polysulfide pulp, which is an area with limited literature. Physical, mechanical and chemical properties of kraft and polysulfide pulps (4% elemental sulfur addition to cooking digester) cooked under the same conditions were studied as regards to their behavior under various PFI refining (0, 3000, 6000, 9000 revs.). Polysulfide (PS) pulping, compared to the kraft method, resulted in higher pulp yield and higher pulp kappa number. Polysulfide also gave pulp having higher tensile and burst index. However, the strength of polysulfide pulp, tear index at a constant tensile index, was found to be 15% lower as compared to the kraft pulp. Refining studies showed that moisture holding ability of chemical pulps mostly depends on the chemical nature of the pulp. Refining effects such as fibrillation and fine content did not have a significant effect on the hygroscopic behavior of chemical pulp.

  5. Choices, Frameworks and Refinement

    NASA Technical Reports Server (NTRS)

    Campbell, Roy H.; Islam, Nayeem; Johnson, Ralph; Kougiouris, Panos; Madany, Peter

    1991-01-01

    In this paper we present a method for designing operating systems using object-oriented frameworks. A framework can be refined into subframeworks. Constraints specify the interactions between the subframeworks. We describe how we used object-oriented frameworks to design Choices, an object-oriented operating system.

  6. Equipment concept design and development plans for microgravity science and applications research on space station: Combustion tunnel, laser diagnostic system, advanced modular furnace, integrated electronics laboratory

    NASA Technical Reports Server (NTRS)

    Uhran, M. L.; Youngblood, W. W.; Georgekutty, T.; Fiske, M. R.; Wear, W. O.

    1986-01-01

    Taking advantage of the microgravity environment of space NASA has initiated the preliminary design of a permanently manned space station that will support technological advances in process science and stimulate the development of new and improved materials having applications across the commercial spectrum. Previous studies have been performed to define from the researcher's perspective, the requirements for laboratory equipment to accommodate microgravity experiments on the space station. Functional requirements for the identified experimental apparatus and support equipment were determined. From these hardware requirements, several items were selected for concept designs and subsequent formulation of development plans. This report documents the concept designs and development plans for two items of experiment apparatus - the Combustion Tunnel and the Advanced Modular Furnace, and two items of support equipment the Laser Diagnostic System and the Integrated Electronics Laboratory. For each concept design, key technology developments were identified that are required to enable or enhance the development of the respective hardware.

  7. Nursing care plans versus concept maps in the enhancement of critical thinking skills in nursing students enrolled in a baccalaureate nursing program.

    PubMed

    Sinatra-Wilhelm, Tina

    2012-01-01

    Appropriate and effective critical thinking and problem solving is necessary for all nurses in order to make complex decisions that improve patient outcomes, safety, and quality of nursing care. With the current emphasis on quality improvement, critical thinking ability is a noteworthy concern within the nursing profession. An in-depth review of literature related to critical thinking was performed. The use of nursing care plans and concept mapping to improve critical thinking skills was among the recommendations identified. This study compares the use of nursing care plans and concept mapping as a teaching strategy for the enhancement of critical thinking skills in baccalaureate level nursing students. The California Critical Thinking Skills Test was used as a method of comparison and evaluation. Results indicate that concept mapping enhances critical thinking skills in baccalaureate nursing students. PMID:22856062

  8. Zone refining of plutonium metal

    SciTech Connect

    1997-05-01

    The purpose of this study was to investigate zone refining techniques for the purification of plutonium metal. The redistribution of 10 impurity elements from zone melting was examined. Four tantalum boats were loaded with plutonium impurity alloy, placed in a vacuum furnace, heated to 700{degrees}C, and held at temperature for one hour. Ten passes were made with each boat. Metallographic and chemical analyses performed on the plutonium rods showed that, after 10 passes, moderate movement of certain elements were achieved. Molten zone speeds of 1 or 2 inches per hour had no effect on impurity element movement. Likewise, the application of constant or variable power had no effect on impurity movement. The study implies that development of a zone refining process to purify plutonium is feasible. Development of a process will be hampered by two factors: (1) the effect on impurity element redistribution of the oxide layer formed on the exposed surface of the material is not understood, and (2) the tantalum container material is not inert in the presence of plutonium. Cold boat studies are planned, with higher temperature and vacuum levels, to determine the effect on these factors. 5 refs., 1 tab., 5 figs.

  9. Strategic planning for the International Space Station

    NASA Technical Reports Server (NTRS)

    Griner, Carolyn S.

    1990-01-01

    The concept for utilization and operations planning for the International Space Station Freedom was developed in a NASA Space Station Operations Task Force in 1986. Since that time the concept has been further refined to definitize the process and products required to integrate the needs of the international user community with the operational capabilities of the Station in its evolving configuration. The keystone to the process is the development of individual plans by the partners, with the parameters and formats common to the degree that electronic communications techniques can be effectively utilized, while maintaining the proper level and location of configuration control. The integration, evaluation, and verification of the integrated plan, called the Consolidated Operations and Utilization Plan (COUP), is being tested in a multilateral environment to prove out the parameters, interfaces, and process details necessary to produce the first COUP for Space Station in 1991. This paper will describe the concept, process, and the status of the multilateral test case.

  10. Issues in adaptive mesh refinement

    SciTech Connect

    Dai, William Wenlong

    2009-01-01

    In this paper, we present an approach for a patch-based adaptive mesh refinement (AMR) for multi-physics simulations. The approach consists of clustering, symmetry preserving, mesh continuity, flux correction, communications, and management of patches. Among the special features of this patch-based AMR are symmetry preserving, efficiency of refinement, special implementation offlux correction, and patch management in parallel computing environments. Here, higher efficiency of refinement means less unnecessarily refined cells for a given set of cells to be refined. To demonstrate the capability of the AMR framework, hydrodynamics simulations with many levels of refinement are shown in both two- and three-dimensions.

  11. Worldwide refining and gas processing directory

    SciTech Connect

    1999-11-01

    Statistics are presented on the following: US refining; Canada refining; Europe refining; Africa refining; Asia refining; Latin American refining; Middle East refining; catalyst manufacturers; consulting firms; engineering and construction; US gas processing; international gas processing; plant maintenance providers; process control and simulation systems; and trade associations.

  12. Minimally refined biomass fuel

    DOEpatents

    Pearson, Richard K.; Hirschfeld, Tomas B.

    1984-01-01

    A minimally refined fluid composition, suitable as a fuel mixture and derived from biomass material, is comprised of one or more water-soluble carbohydrates such as sucrose, one or more alcohols having less than four carbons, and water. The carbohydrate provides the fuel source; water solubilizes the carbohydrates; and the alcohol aids in the combustion of the carbohydrate and reduces the vicosity of the carbohydrate/water solution. Because less energy is required to obtain the carbohydrate from the raw biomass than alcohol, an overall energy savings is realized compared to fuels employing alcohol as the primary fuel.

  13. Research on Curriculum Plan and Learning Achievement for Aromatherapy with the Concept of the Chinese Five Elements

    ERIC Educational Resources Information Center

    Hsu, Pei-Ching

    2012-01-01

    In Taiwan, people are getting more aware of beauty treatments and the concept of health care. This study hopes to bring all relevant concepts such as Aromatherapy, essential scented oils, medical foods, human meridians, Chinese five elements therapy, and beauty business management into the curriculum design, and seriously considered many factors…

  14. Double Stimulation in Strategic Concept Formation: An Activity-Theoretical Analysis of Business Planning in a Small Technology Firm

    ERIC Educational Resources Information Center

    Virkkunen, Jaakko; Ristimaki, Paivi

    2012-01-01

    In this article, we study the relationships between culturally existing general strategy concepts and a small information and communication technology firm's specific strategic challenge in its management team's search for a new strategy concept. We apply three theoretical ideas of cultural historical activity theory: (a) the idea of double…

  15. Refining primary lead by granulation-leaching-electrowinning

    NASA Astrophysics Data System (ADS)

    Ojebuoboh, F.; Wang, S.; Maccagni, M.

    2003-04-01

    This article describes the development of a new process in which lead bullion obtained from smelting concentrates is refined by leaching-electrowinning. In the last half century, the challenge to treat and refine lead in order to minimize emissions of lead and lead compounds has intensified. Within the primary lead industry, the treatment aspect has transformed from the sinter-blast furnace model to direct smelting, creating gains in hygiene, environmental control, and efficiency. The refining aspect has remained based on kettle refining, or to a lesser extent, the Betts electrolytic refining. In the mid-1990s, Asarco investigated a concept based on granulating the lead bullion from the blast furnace. The granular material was fed into the Engitec Fluobor process. This work resulted in the operation of a 45 kg/d pilot plant that could produce lead sheets of 99.9% purity.

  16. Hirshfeld atom refinement

    PubMed Central

    Capelli, Silvia C.; Bürgi, Hans-Beat; Dittrich, Birger; Grabowsky, Simon; Jayatilaka, Dylan

    2014-01-01

    Hirshfeld atom refinement (HAR) is a method which determines structural parameters from single-crystal X-ray diffraction data by using an aspherical atom partitioning of tailor-made ab initio quantum mechanical molecular electron densities without any further approximation. Here the original HAR method is extended by implementing an iterative procedure of successive cycles of electron density calculations, Hirshfeld atom scattering factor calculations and structural least-squares refinements, repeated until convergence. The importance of this iterative procedure is illustrated via the example of crystalline ammonia. The new HAR method is then applied to X-ray diffraction data of the dipeptide Gly–l-Ala measured at 12, 50, 100, 150, 220 and 295 K, using Hartree–Fock and BLYP density functional theory electron densities and three different basis sets. All positions and anisotropic displacement parameters (ADPs) are freely refined without constraints or restraints – even those for hydrogen atoms. The results are systematically compared with those from neutron diffraction experiments at the temperatures 12, 50, 150 and 295 K. Although non-hydrogen-atom ADPs differ by up to three combined standard uncertainties (csu’s), all other structural parameters agree within less than 2 csu’s. Using our best calculations (BLYP/cc-pVTZ, recommended for organic molecules), the accuracy of determining bond lengths involving hydrogen atoms from HAR is better than 0.009 Å for temperatures of 150 K or below; for hydrogen-atom ADPs it is better than 0.006 Å2 as judged from the mean absolute X-ray minus neutron differences. These results are among the best ever obtained. Remarkably, the precision of determining bond lengths and ADPs for the hydrogen atoms from the HAR procedure is comparable with that from the neutron measurements – an outcome which is obtained with a routinely achievable resolution of the X-ray data of 0.65 Å. PMID:25295177

  17. Applying Marketing Concepts to Higher Education: Development of an Enrollment Management Plan for the Off-Campus Program.

    ERIC Educational Resources Information Center

    Blanchard, Bryan

    The Enrollment Management Plan proposed in this report was developed in an effort to provide a comprehensive framework for organizational analysis, planning, and evaluation for the Off-Campus Program of the Community College of Rhode Island. The introductory sections of the report offer background information, define enrollment management, and…

  18. Thailand: refining cultural values.

    PubMed

    Ratanakul, P

    1990-01-01

    In the second of a set of three articles concerned with "bioethics on the Pacific Rim," Ratanakul, director of a research center for Southeast Asian cultures in Thailand, provides an overview of bioethical issues in his country. He focuses on four issues: health care allocation, AIDS, determination of death, and euthanasia. The introduction of Western medicine into Thailand has brought with it a multitude of ethical problems created in part by tension between Western and Buddhist values. For this reason, Ratanakul concludes that "bioethical enquiry in Thailand must not only examine ethical dilemmas that arise in the actual practice of medicine and research in the life sciences, but must also deal with the refinement and clarification of applicable Thai cultural and moral values." PMID:2318624

  19. Replacement, reduction and refinement.

    PubMed

    Flecknell, Paul

    2002-01-01

    In 1959, William Russell and Rex Burch published "The Principles of Humane Experimental Technique". They proposed that if animals were to be used in experiments, every effort should be made to Replace them with non-sentient alternatives, to Reduce to a minimum the number of animals used, and to Refine experiments which used animals so that they caused the minimum pain and distress. These guiding principles, the "3 Rs" of animal research, were initially given little attention. Gradually, however, they have become established as essential considerations when animals are used in research. They have influenced new legislation aimed at controlling the use of experimental animals, and in the United Kingdom they have become formally incorporated into the Animal (Scientific) Procedures Act. The three principles, of Replacement, Reduction and Refinement, have also proven to be an area of common ground for research workers who use animals, and those who oppose their use. Scientists, who accept the need to use animals in some experiments, would also agree that it would be preferable not to use animals. If animals were to be used, as few as possible should be used and they should experience a minimum of pain or distress. Many of those who oppose animal experimentation, would also agree that until animal experimentation is stopped, Russell and Burch's 3Rs provide a means to improve animal welfare. It has also been recognised that adoption of the 3Rs can improve the quality of science. Appropriately designed experiments that minimise variation, provide standardised optimum conditions of animals care and minimise unnecessary stress or pain, often yield better more reliable data. Despite the progress made as a result of attention to these principles, several major problems have been identified. When replacing animals with alternative methods, it has often proven difficult to formally validate the alternative. This has proven a particular problem in regulatory toxicology

  20. Towards automated crystallographic structure refinement with phenix.refine.

    PubMed

    Afonine, Pavel V; Grosse-Kunstleve, Ralf W; Echols, Nathaniel; Headd, Jeffrey J; Moriarty, Nigel W; Mustyakimov, Marat; Terwilliger, Thomas C; Urzhumtsev, Alexandre; Zwart, Peter H; Adams, Paul D

    2012-04-01

    phenix.refine is a program within the PHENIX package that supports crystallographic structure refinement against experimental data with a wide range of upper resolution limits using a large repertoire of model parameterizations. It has several automation features and is also highly flexible. Several hundred parameters enable extensive customizations for complex use cases. Multiple user-defined refinement strategies can be applied to specific parts of the model in a single refinement run. An intuitive graphical user interface is available to guide novice users and to assist advanced users in managing refinement projects. X-ray or neutron diffraction data can be used separately or jointly in refinement. phenix.refine is tightly integrated into the PHENIX suite, where it serves as a critical component in automated model building, final structure refinement, structure validation and deposition to the wwPDB. This paper presents an overview of the major phenix.refine features, with extensive literature references for readers interested in more detailed discussions of the methods. PMID:22505256

  1. Towards automated crystallographic structure refinement with phenix.refine

    PubMed Central

    Afonine, Pavel V.; Grosse-Kunstleve, Ralf W.; Echols, Nathaniel; Headd, Jeffrey J.; Moriarty, Nigel W.; Mustyakimov, Marat; Terwilliger, Thomas C.; Urzhumtsev, Alexandre; Zwart, Peter H.; Adams, Paul D.

    2012-01-01

    phenix.refine is a program within the PHENIX package that supports crystallographic structure refinement against experimental data with a wide range of upper resolution limits using a large repertoire of model parameterizations. It has several automation features and is also highly flexible. Several hundred parameters enable extensive customizations for complex use cases. Multiple user-defined refinement strategies can be applied to specific parts of the model in a single refinement run. An intuitive graphical user interface is available to guide novice users and to assist advanced users in managing refinement projects. X-ray or neutron diffraction data can be used separately or jointly in refinement. phenix.refine is tightly integrated into the PHENIX suite, where it serves as a critical component in automated model building, final structure refinement, structure validation and deposition to the wwPDB. This paper presents an overview of the major phenix.refine features, with extensive literature references for readers interested in more detailed discussions of the methods. PMID:22505256

  2. Virtual 3D planning and patient specific surgical guides for osteotomies around the knee: a feasibility and proof-of-concept study.

    PubMed

    Victor, J; Premanathan, A

    2013-11-01

    We have investigated the benefits of patient specific instrument guides, applied to osteotomies around the knee. Single, dual and triple planar osteotomies were performed on tibias or femurs in 14 subjects. In all patients, a detailed pre-operative plan was prepared based upon full leg standing radiographic and CT scan information. The planned level of the osteotomy and open wedge resection was relayed to the surgery by virtue of a patient specific guide developed from the images. The mean deviation between the planned wedge angle and the executed wedge angle was 0° (-1 to 1, sd 0.71) in the coronal plane and 0.3° (-0.9 to 3, sd 1.14) in the sagittal plane. The mean deviation between the planned hip, knee, ankle angle (HKA) on full leg standing radiograph and the post-operative HKA was 0.3° (-1 to 2, sd 0.75). It is concluded that this is a feasible and valuable concept from the standpoint of pre-operative software based planning, surgical application and geometrical accuracy of outcome. PMID:24187376

  3. Refinement of protein dynamic structure: normal mode refinement.

    PubMed Central

    Kidera, A; Go, N

    1990-01-01

    An x-ray crystallographic refinement method, referred to as the normal mode refinement, is proposed. The Debye-Waller factor is expanded in terms of the effective normal modes whose amplitudes and eigenvectors are experimentally determined by the crystallographic refinement. In contrast to the conventional method, the atomic motions are treated generally as anisotropic and concerted. This method is assessed by using the simulated x-ray data given by a Monte Carlo simulation of human lysozyme. In this article, we refine the dynamic structure by fixing the average static structure to exact coordinates. It is found that the normal mode refinement, using a smaller number of variables, gives a better R factor and more information on the dynamics (anisotropy and collectivity in the motion). Images PMID:2339115

  4. Gradualness facilitates knowledge refinement.

    PubMed

    Rada, R

    1985-05-01

    To facilitate knowledge refinement, a system should be designed so that small changes in the knowledge correspond to small changes in the function or performance of the system. Two sets of experiments show the value of small, heuristically guided changes in a weighted rule base. In the first set, the ordering among numbers (reflecting certainties) makes their manipulation more straightforward than the manipulation of relationships. A simple credit assignment and weight adjustment strategy for improving numbers in a weighted, rule-based expert system is presented. In the second set, the rearrangement of predicates benefits from additional knowledge about the ``ordering'' among predicates. A third set of experiments indicates the importance of the proper level of granularity when augmenting a knowledge base. Augmentation of one knowledge base by analogical reasoning from another knowledge base did not work with only binary relationships, but did succeed with ternary relationships. To obtain a small improvement in the knowledge base, a substantial amount of structure had to be treated as a unit. PMID:21869290

  5. Study and Demonstration of Planning and Scheduling Concepts for the Earth Observing System Data and Information System

    NASA Technical Reports Server (NTRS)

    Davis, Randal; Thalman, Nancy

    1993-01-01

    The University of Colorado's Laboratory for Atmospheric and Space Physics (CU/LASP) along with the Goddard Space Flight Center (GSFC) and the Jet Propulsion Laboratory (JPL) designed, implemented, tested, and demonstrated a prototype of the distributed, hierarchical planning and scheduling system comtemplated for the Earth Observing System (EOS) project. The planning and scheduling prototype made use of existing systems: CU/LASP's Operations and Science Instrument Support Planning and Scheduling (OASIS-PS) software package; GSFC's Request Oriented Scheduling Engine (ROSE); and JPL's Plan Integrated Timeliner 2 (Plan-It-2). Using these tools, four scheduling nodes were implemented and tied together using a new communications protocol for scheduling applications called the Scheduling Applications Interface Language (SAIL). An extensive and realistic scenario of EOS satellite operations was then developed and the prototype scheduling system was tested and demonstrated using the scenario. Two demonstrations of the system were given to NASA personnel and EOS core system (ECS) contractor personnel. A comprehensive volume of lessons learned was generated and a meeting was held with NASA and ECS representatives to review these lessons learned. A paper and presentation on the project's final results was given at the American Institute of Aeronautics and Astronautics Computing in Aerospace 9 conference.

  6. Post LANDSAT D Advanced Concept Evaluation (PLACE). [with emphasis on mission planning, technological forecasting, and user requirements

    NASA Technical Reports Server (NTRS)

    1977-01-01

    An outline is given of the mission objectives and requirements, system elements, system concepts, technology requirements and forecasting, and priority analysis for LANDSAT D. User requirements and mission analysis and technological forecasting are emphasized. Mission areas considered include agriculture, range management, forestry, geology, land use, water resources, environmental quality, and disaster assessment.

  7. Fertility Decision-Making Among Kenyan HIV-Serodiscordant Couples Who Recently Conceived: Implications for Safer Conception Planning.

    PubMed

    Pintye, Jillian; Ngure, Kenneth; Curran, Kathryn; Vusha, Sophie; Mugo, Nelly; Celum, Connie; Baeten, Jared M; Heffron, Renee

    2015-09-01

    HIV-serodiscordant couples often choose to attempt pregnancy despite their HIV transmission risk. Optimizing delivery of HIV risk reduction strategies during peri-conception periods (i.e., safer conception) requires understanding how HIV-serodiscordant couples approach fertility decisions. We conducted 36 in-depth individual interviews with male and female partners of Kenyan heterosexual HIV-serodiscordant couples who recently conceived. Transcripts were analyzed by gender and HIV serostatus using open coding. Matrices were used to identify patterns and emerging themes. Most participants expressed acceptance of being in an HIV-serodiscordant couple and affirmed their resilience to live with serodiscordance and achieve their fertility goals. Overall, while the goal for childbearing was unchanged, conception became an urgent desire so that both partners could experience childrearing together while the HIV-infected partner was still healthy. Children also add value to the relationship, and multiple children were a commonly expressed desire. Couples' desires dominated those of individual partners in fertility decision-making, but male preferences were more influential when the individual desires differed. Values and preferences of the couple as a unit may mediate fertility decision-making in HIV-discordant couples. Thus, it is important that safer conception programs include both partners when appropriate and consider the relationship context during risk reduction counseling and when recommending risk reduction interventions. PMID:26301703

  8. Integrating management tools and concepts to develop an estuarine planning support system: A case study of the Humber Estuary, Eastern England.

    PubMed

    Lonsdale, Jemma-Anne; Weston, Keith; Barnard, Steve; Boyes, Suzanne J; Elliott, Michael

    2015-11-15

    Estuaries are important because of their multiple uses and users which often makes them challenging to manage since management must strike a balance between the needs of users, the estuaries' ecological and economic value and the context of multiple legislative drivers. To facilitate management we have therefore developed an Estuarine Planning Support System (EPSS) framework using the Humber Estuary, Eastern England, as a case study which integrates the current legislation tools and concepts. This integrated EPSS framework is an improvement on previous approaches for assessing cumulative impacts as it takes into account legislative drivers, management tools and other mechanisms for controlling plans/projects specific to the estuary. It therefore enables managers and users to assess and address both the current state and the way in which a new industrial, port or urban development could impact an estuary in an accessible and understandable framework. PMID:26342391

  9. Creative Concept Mapping.

    ERIC Educational Resources Information Center

    Brown, David S.

    2002-01-01

    Recommends the use of concept mapping in science teaching and proposes that it be presented as a creative activity. Includes a sample lesson plan of a potato stamp concept mapping activity for astronomy. (DDR)

  10. Crystal structure refinement with SHELXL

    SciTech Connect

    Sheldrick, George M.

    2015-01-01

    New features added to the refinement program SHELXL since 2008 are described and explained. The improvements in the crystal structure refinement program SHELXL have been closely coupled with the development and increasing importance of the CIF (Crystallographic Information Framework) format for validating and archiving crystal structures. An important simplification is that now only one file in CIF format (for convenience, referred to simply as ‘a CIF’) containing embedded reflection data and SHELXL instructions is needed for a complete structure archive; the program SHREDCIF can be used to extract the .hkl and .ins files required for further refinement with SHELXL. Recent developments in SHELXL facilitate refinement against neutron diffraction data, the treatment of H atoms, the determination of absolute structure, the input of partial structure factors and the refinement of twinned and disordered structures. SHELXL is available free to academics for the Windows, Linux and Mac OS X operating systems, and is particularly suitable for multiple-core processors.

  11. Increasing Student Interest and Comprehension of Production Planning and Control and Operations Performance Measurement Concepts Using a Production Line Game

    ERIC Educational Resources Information Center

    Cox, James F., III; Walker, Edward D., II

    2005-01-01

    Production planning and control (PPC) systems and operations performance measures are topics that students generally find both boring and difficult to understand. In the article, the authors present a production line game that they have found to be an effective tool to increase student interest in the topics as well as student comprehension. The…

  12. Parallel Adaptive Mesh Refinement

    SciTech Connect

    Diachin, L; Hornung, R; Plassmann, P; WIssink, A

    2005-03-04

    As large-scale, parallel computers have become more widely available and numerical models and algorithms have advanced, the range of physical phenomena that can be simulated has expanded dramatically. Many important science and engineering problems exhibit solutions with localized behavior where highly-detailed salient features or large gradients appear in certain regions which are separated by much larger regions where the solution is smooth. Examples include chemically-reacting flows with radiative heat transfer, high Reynolds number flows interacting with solid objects, and combustion problems where the flame front is essentially a two-dimensional sheet occupying a small part of a three-dimensional domain. Modeling such problems numerically requires approximating the governing partial differential equations on a discrete domain, or grid. Grid spacing is an important factor in determining the accuracy and cost of a computation. A fine grid may be needed to resolve key local features while a much coarser grid may suffice elsewhere. Employing a fine grid everywhere may be inefficient at best and, at worst, may make an adequately resolved simulation impractical. Moreover, the location and resolution of fine grid required for an accurate solution is a dynamic property of a problem's transient features and may not be known a priori. Adaptive mesh refinement (AMR) is a technique that can be used with both structured and unstructured meshes to adjust local grid spacing dynamically to capture solution features with an appropriate degree of resolution. Thus, computational resources can be focused where and when they are needed most to efficiently achieve an accurate solution without incurring the cost of a globally-fine grid. Figure 1.1 shows two example computations using AMR; on the left is a structured mesh calculation of a impulsively-sheared contact surface and on the right is the fuselage and volume discretization of an RAH-66 Comanche helicopter [35]. Note the

  13. Disaster planning: the past, present, and future concepts and principles of managing a surge of burn injured patients for those involved in hospital facility planning and preparedness.

    PubMed

    Kearns, Randy D; Holmes, James H; Alson, Roy L; Cairns, Bruce A

    2014-01-01

    The 9/11 attacks reframed the narrative regarding disaster medicine. Bypass strategies have been replaced with absorption strategies and are more specifically described as "surge capacity." In the succeeding years, a consensus has coalesced around stratifying the surge capacity into three distinct tiers: conventional, contingency, and crisis surge capacities. For the purpose of this work, these three distinct tiers were adapted specifically to burn surge for disaster planning activities at hospitals where burn centers are not located. A review was conducted involving published plans, other related academic works, and findings from actual disasters as well as modeling. The aim was to create burn-specific definitions for surge capacity for hospitals where a burn center is not located. The three-tier consensus description of surge capacity is delineated in their respective stratifications by what will hereinafter be referred to as the three "S's"; staff, space, and supplies (also referred to as supplies, pharmaceuticals, and equipment). This effort also included the creation of a checklist for nonburn center hospitals to assist in their development of a burn surge plan. Patients with serious burn injuries should always be moved to and managed at burn centers, but during a medical disaster with significant numbers of burn injured patients, there may be impediments to meeting this goal. It may be necessary for burn injured patients to remain for hours in an outlying hospital until being moved to a burn center. This work was aimed at aiding local and regional hospitals in developing an extemporizing measure until their burn injured patients can be moved to and managed at a burn center(s). PMID:23817001

  14. Solar High-energy Astrophysical Plasmas Explorer (SHAPE). Volume 1: Proposed concept, statement of work and cost plan

    NASA Technical Reports Server (NTRS)

    Dennis, Brian R.; Martin, Franklin D.; Prince, T.; Lin, R.; Bruner, M.; Culhane, L.; Ramaty, R.; Doschek, G.; Emslie, G.; Lingenfelter, R.

    1986-01-01

    The concept of the Solar High-Energy Astrophysical Plasmas Explorer (SHAPE) is studied. The primary goal is to understand the impulsive release of energy, efficient acceleration of particles to high energies, and rapid transport of energy. Solar flare studies are the centerpieces of the investigation because in flares these high energy processes can be studied in unmatched detail at most wavelenth regions of the electromagnetic spectrum as well as in energetic charged particles and neutrons.

  15. The new concept of hospital--the strategic plan of the "Policlinico A. Gemelli" and positioning of the reengineering project.

    PubMed

    Cicchetti, A

    1998-01-01

    The innovations introduced in the Italian Health Care System by the legislative decrees No. 502/92 and 517/93 are remarkable, drawing on managerial methods and organizational structure of hospitals. To face this kind of change, in 1995 the "Policlinico A. Gemelli" prepared a five-year Strategic Plan that gave strategical lines and targets to be pursued. This plan has isolated 3 main strategical projects to be implemented with the participation of all medical and managerial professionals operating in the "Policlinico". The most complex project is that of the reengineering of management processes, we expect to end during 1998. The main target is to check the fundamental factors involved with the aim of achieving patient satisfaction as well as a cost-effective management. PMID:9689846

  16. Language and Tool Support for Class and State Machine Refinement in UML-B

    NASA Astrophysics Data System (ADS)

    Said, Mar Yah; Butler, Michael; Snook, Colin

    UML-B is a ‘UML-like’ graphical front end for Event-B that provides support for object-oriented modelling concepts. In particular, UML-B supports class diagrams and state machines, concepts that are not explicitly supported in plain Event-B. In Event-B, refinement is used to relate system models at different abstraction levels. The same abstraction-refinement concepts can also be applied in UML-B. This paper introduces the notions of refined classes and refined state machines to enable refinement of classes and state machines in UML-B. Together with these notions, a technique for moving an event between classes to facilitate abstraction is also introduced. Our work makes explicit the structures of class and state machine refinement in UML-B. The UML-B drawing tool and Event-B translator are extended to support the new refinement concepts. A case study of an auto teller machine (ATM) is presented to demonstrate application and effectiveness of refined classes and refined state machines.

  17. Concept of Operations for Data Fusion Visualization

    SciTech Connect

    T.R. McJunkin; R.L. Boring; M.A. McQueen; L.P. Shunn; J.L. Wright; D.I. Gertman; O. Linda; K. McCarty; M. Manic

    2011-09-01

    Situational awareness in the operations and supervision of a industrial system means that decision making entity, whether machine or human, have the important data presented in a timely manner. An optimal presentation of information such that the operator has the best opportunity accurately interpret and react to anomalies due to system degradation, failures or adversaries. Anticipated problems are a matter for system design; however, the paper will focus on concepts for situational awareness enhancement for a human operator when the unanticipated or unaddressed event types occur. Methodology for human machine interface development and refinement strategy is described for a synthetic fuels plant model. A novel concept for adaptively highlighting the most interesting information in the system and a plan for testing the methodology is described.

  18. Space transfer concepts and analysis for exploration missions. Implementation plan and element description document (draft final). Volume 6: Lunar systems

    NASA Technical Reports Server (NTRS)

    1991-01-01

    NASA's two Office of Space Flight (Code M) Space Transfer Vehicle (STV) contractors supported development of Space Exploration Initiative (SEI) lunar transportation concepts. This work treated lunar SEI missions as the far end of a more near-term STV program, most of whose missions were satellite delivery and servicing requirements derived from Civil Needs Data Base (CNDB) projections. Space Transfer Concepts and Analysis for Exploration Missions (STCAEM) began to address the complete design of a lunar transportation system. The following challenges were addressed: (1) the geometry of aerobraking; (2) accommodation of mixed payloads; (3) cryogenic propellant transfer in Low Lunar Orbit (LLO); (4) fully re-usable design; and (5) growth capability. The leveled requirements, derived requirements, and assumptions applied to the lunar transportation system design are discussed. The mission operations section includes data on mission analysis studies and performance parametrics as well as the operating modes and performance evaluations which include the STCAEM recommendations. Element descriptions for the lunar transportation family included are a listing of the lunar transfer vehicle/lunar excursion vehicle (LTV/LEV) components; trade studies and mass analyses of the transfer and excursion modules; advanced crew recovery vehicle (ACRV) (modified crew recovery vehicle (MCRV)) modifications required to fulfill lunar operations; the aerobrake shape and L/D to be used; and some costing methods and results. Commonality and evolution issues are also discussed.

  19. A Key Concept: Spatial Organization

    ERIC Educational Resources Information Center

    Kostrowicki, Jerzy

    1975-01-01

    The application of geography to spatial planning is discussed. Concepts presented include the regional concept, the typological concept, and spatial structure, spatial processes, and spatial organization. For address of journal see SO 504 028. (Author/RM)

  20. Crystal structure refinement with SHELXL

    PubMed Central

    Sheldrick, George M.

    2015-01-01

    The improvements in the crystal structure refinement program SHELXL have been closely coupled with the development and increasing importance of the CIF (Crystallographic Information Framework) format for validating and archiving crystal structures. An important simplification is that now only one file in CIF format (for convenience, referred to simply as ‘a CIF’) containing embedded reflection data and SHELXL instructions is needed for a complete structure archive; the program SHREDCIF can be used to extract the .hkl and .ins files required for further refinement with SHELXL. Recent developments in SHELXL facilitate refinement against neutron diffraction data, the treatment of H atoms, the determination of absolute structure, the input of partial structure factors and the refinement of twinned and disordered structures. SHELXL is available free to academics for the Windows, Linux and Mac OS X operating systems, and is particularly suitable for multiple-core processors. PMID:25567568

  1. A Refined Item Digraph Analysis of a Proportional Reasoning Test.

    ERIC Educational Resources Information Center

    Bart, William M.; Williams-Morris, Ruth

    1990-01-01

    Refined item digraph analysis (RIDA) is a way of studying diagnostic and prescriptive testing. It permits assessment of a test item's diagnostic value by examining the extent to which the item has properties of ideal items. RIDA is illustrated with the Orange Juice Test, which assesses the proportionality concept. (TJH)

  2. Adaptive Mesh Refinement in CTH

    SciTech Connect

    Crawford, David

    1999-05-04

    This paper reports progress on implementing a new capability of adaptive mesh refinement into the Eulerian multimaterial shock- physics code CTH. The adaptivity is block-based with refinement and unrefinement occurring in an isotropic 2:1 manner. The code is designed to run on serial, multiprocessor and massive parallel platforms. An approximate factor of three in memory and performance improvements over comparable resolution non-adaptive calculations has-been demonstrated for a number of problems.

  3. Refining the shifted topological vertex

    SciTech Connect

    Drissi, L. B.; Jehjouh, H.; Saidi, E. H.

    2009-01-15

    We study aspects of the refining and shifting properties of the 3d MacMahon function C{sub 3}(q) used in topological string theory and BKP hierarchy. We derive the explicit expressions of the shifted topological vertex S{sub {lambda}}{sub {mu}}{sub {nu}}(q) and its refined version T{sub {lambda}}{sub {mu}}{sub {nu}}(q,t). These vertices complete results in literature.

  4. Applying the theory of planned behaviour to multiple sclerosis patients’ decisions on disease modifying therapy – questionnaire concept and validation

    PubMed Central

    2012-01-01

    Background Patients making important medical decisions need to evaluate complex information in the light of their own beliefs, attitudes and priorities. The process can be considered in terms of the theory of planned behaviour. Decision support technologies aim at helping patients making informed treatment choices. Instruments assessing informed choices need to include risk knowledge, attitude (towards therapy) and actual uptake. However, mechanisms by which decision support achieves its goals are poorly understood. Our aim was therefore to develop and validate an instrument modeling the process of multiple sclerosis (MS) patients’ decision making about whether to undergo disease modifying (immuno-)therapies (DMT). Methods We constructed a 30-item patient administered questionnaire to access the elaboration of decisions about DMT in MS according to the theory of planned behaviour. MS-patients’ belief composites regarding immunotherapy were classified according to the domains “attitude”, “subjective social norm” and “control beliefs” and within each domain to either “expectations” or “values” yielding 6 sub-domains. A randomized controlled trial (n = 192) evaluating an evidence based educational intervention tested the instrument’s predictive power regarding intention to use immunotherapy and its sensitivity to the intervention. Results The psychometric properties of the questionnaire were satisfactory (mean item difficulty 62, mean SD 0.9, range 0–3). Responses explain up to 68% of the variability in the intention to use DMT was explained by up to 68% in the total sample. Four weeks after an educational intervention, predictive power was higher in the intervention (IG) compared to the control group (CG) (intention estimate: CG 56% / IG 69%, p = .179; three domains CG 56% / IG 74%, p = .047; six sub-domains CG 64% / IG 78%, p = .073). The IG held more critical beliefs towards immunotherapy (p = .002) and were less

  5. Whole-body hybrid imaging concept for the integration of PET/MR into radiation therapy treatment planning.

    PubMed

    Paulus, Daniel H; Oehmigen, Mark; Grüneisen, Johannes; Umutlu, Lale; Quick, Harald H

    2016-05-01

    Modern radiation therapy (RT) treatment planning is based on multimodality imaging. With the recent availability of whole-body PET/MR hybrid imaging new opportunities arise to improve target volume delineation in RT treatment planning. This, however, requires dedicated RT equipment for reproducible patient positioning on the PET/MR system, which has to be compatible with MR and PET imaging. A prototype flat RT table overlay, radiofrequency (RF) coil holders for head imaging, and RF body bridges for body imaging were developed and tested towards PET/MR system integration. Attenuation correction (AC) of all individual RT components was performed by generating 3D CT-based template models. A custom-built program for μ-map generation assembles all AC templates depending on the presence and position of each RT component. All RT devices were evaluated in phantom experiments with regards to MR and PET imaging compatibility, attenuation correction, PET quantification, and position accuracy. The entire RT setup was then evaluated in a first PET/MR patient study on five patients at different body regions. All tested devices are PET/MR compatible and do not produce visible artifacts or disturb image quality. The RT components showed a repositioning accuracy of better than 2 mm. Photon attenuation of  -11.8% in the top part of the phantom was observable, which was reduced to  -1.7% with AC using the μ-map generator. Active lesions of 3 subjects were evaluated in terms of SUVmean and an underestimation of  -10.0% and  -2.4% was calculated without and with AC of the RF body bridges, respectively. The new dedicated RT equipment for hybrid PET/MR imaging enables acquisitions in all body regions. It is compatible with PET/MR imaging and all hardware components can be corrected in hardware AC by using the suggested μ-map generator. These developments provide the technical and methodological basis for integration of PET/MR hybrid imaging into RT planning. PMID

  6. Whole-body hybrid imaging concept for the integration of PET/MR into radiation therapy treatment planning

    NASA Astrophysics Data System (ADS)

    Paulus, Daniel H.; Oehmigen, Mark; Grueneisen, Johannes; Umutlu, Lale; Quick, Harald H.

    2016-05-01

    Modern radiation therapy (RT) treatment planning is based on multimodality imaging. With the recent availability of whole-body PET/MR hybrid imaging new opportunities arise to improve target volume delineation in RT treatment planning. This, however, requires dedicated RT equipment for reproducible patient positioning on the PET/MR system, which has to be compatible with MR and PET imaging. A prototype flat RT table overlay, radiofrequency (RF) coil holders for head imaging, and RF body bridges for body imaging were developed and tested towards PET/MR system integration. Attenuation correction (AC) of all individual RT components was performed by generating 3D CT-based template models. A custom-built program for μ-map generation assembles all AC templates depending on the presence and position of each RT component. All RT devices were evaluated in phantom experiments with regards to MR and PET imaging compatibility, attenuation correction, PET quantification, and position accuracy. The entire RT setup was then evaluated in a first PET/MR patient study on five patients at different body regions. All tested devices are PET/MR compatible and do not produce visible artifacts or disturb image quality. The RT components showed a repositioning accuracy of better than 2 mm. Photon attenuation of  ‑11.8% in the top part of the phantom was observable, which was reduced to  ‑1.7% with AC using the μ-map generator. Active lesions of 3 subjects were evaluated in terms of SUVmean and an underestimation of  ‑10.0% and  ‑2.4% was calculated without and with AC of the RF body bridges, respectively. The new dedicated RT equipment for hybrid PET/MR imaging enables acquisitions in all body regions. It is compatible with PET/MR imaging and all hardware components can be corrected in hardware AC by using the suggested μ-map generator. These developments provide the technical and methodological basis for integration of PET/MR hybrid imaging into RT planning.

  7. Preparing for new business directions in competitive markets. The concept phase of an integrated business planning process

    SciTech Connect

    Norton, G.; Wahlin, D.

    1997-09-01

    With deregulation, electric utilities face previously unknown threats as their franchise markets have been opened to competitors such as power marketers who want to wheel power into distribution grids, independent power producers, co-generation firms who want to take the biggest customers off the grid, and many others (including hostile utilities eyeing value in under-performing stocks). On the other hand, firms are now presented with opportunities they have not had in decades, if ever, to sell to customers in other, formerly protected franchise territories, invest in new businesses, or use internal expertise and experience to create new products and services for existing customers or entirely new customers and markets. Utilities are entering businesses as diverse as maintenance services, retail appliance stores, and telecommunications. This paper will discuss how to evaluate and plan for some of the opportunities available to the electric utilities as the result of changes in FERC, state utility regulations, and proposed legislation.

  8. Ultrasonic sensor to characterize wood pulp during refining.

    PubMed

    Greenwood, M S; Panetta, P D; Bond, L J; McCaw, M W

    2006-12-22

    A novel sensor concept has been developed for measuring the degree of refining, the water retention value (WRV), and the weight percentage of wood pulp during the refining process. The measurement time is less than 5 min and the sensor can operate in a slip-stream of the process line or as an at-line instrument. The degree of refining and the WRV are determined from settling measurements. The settling of a pulp suspension (with a weight percentage less than 0.5 wt%) is observed, after the mixer, which keeps the pulp uniformly distributed, is turned off. The attenuation of ultrasound as a function of time is recorded and these data show a peak at a time designated as the "peak time." The peak time T increases with the degree of refining, as demonstrated by measuring pulp samples with known degrees of refining. The WRV can be determined using the relative peak time, defined as the ratio T(2)/T(1), where T(1) is an initial peak time and T(2) is the value after additional refining. This method offers an alternative WRV test for the industry to the current time-consuming method. PMID:16920173

  9. Ultrasonic Sensor to Characterize Wood Pulp During Refining

    SciTech Connect

    Greenwood, Margaret S.; Panetta, Paul D.; Bond, Leonard J.; McCaw, M. W.

    2006-12-22

    A novel sensor concept has been developed for measuring the consistency, the degree of refining, the water retention value (WRV), and the consistency of wood pulp during the refining process. The measurement time is less than 5 minutes and the sensor can operate in a slip-stream of the process line or as an at-line instrument. The consistency is obtained from a calibration, in which the attenuation of ultrasound through the pulp suspension is measured as a function of the solids weight percentage. The degree of refining and the WRV are determined from settling measurements. The settling of a pulp suspension (consistency less than 0.5 Wt%) is observed, after the mixer that keeps the pulp uniformly distributed is turned off. The attenuation of ultrasound as a function of time is recorded and these data show a peak, after a certain delay, defined as the “peak time.” The degree of refining increases with the peak time, as demonstrated by measuring pulp samples with different degrees of refining. The WRV can be determined using the relative peak time, defined as the ratio T2/T1, where T1 is an initial value of the peak time and T2 is the value after additional refining. This method offers an additional WRV test for the industry, because the freeness test is not specific for the WRV.

  10. Model Refinement Using Eigensystem Assignment

    NASA Technical Reports Server (NTRS)

    Maghami, Peiman G.

    2000-01-01

    IA novel approach for the refinement of finite-element-based analytical models of flexible structures is presented. The proposed approach models the possible refinements in the mass, damping, and stiffness matrices of the finite element model in the form of a constant gain feedback with acceleration, velocity, and displacement measurements, respectively. Once the free elements of the structural matrices have been defined, the problem of model refinement reduces to obtaining position, velocity, and acceleration gain matrices with appropriate sparsity that reassign a desired subset of the eigenvalues of the model, along with partial mode shapes, from their baseline values to those obtained from system identification test data. A sequential procedure is used to assign one conjugate pair of eigenvalues at each step using symmetric output feedback gain matrices, and the eigenvectors are partially assigned, while ensuring that the eigenvalues assigned in the previous steps are not disturbed. The procedure can also impose that gain matrices be dissipative to guarantee the stability of the refined model. A numerical example, involving finite element model refinement for a structural testbed at NASA Langley Research Center (Controls-Structures-Interaction Evolutionary model) is presented to demonstrate the feasibility of the proposed approach.

  11. Zone refining of plutonium metal

    SciTech Connect

    Blau, M.S.

    1994-08-01

    The zone refining process was applied to Pu metal containing known amounts of impurities. Rod specimens of plutonium metal were melted into and contained in tantalum boats, each of which was passed horizontally through a three-turn, high-frequency coil in such a manner as to cause a narrow molten zone to pass through the Pu metal rod 10 times. The impurity elements Co, Cr, Fe, Ni, Np, U were found to move in the same direction as the molten zone as predicted by binary phase diagrams. The elements Al, Am, and Ga moved in the opposite direction of the molten zone as predicted by binary phase diagrams. As the impurity alloy was zone refined, {delta}-phase plutonium metal crystals were produced. The first few zone refining passes were more effective than each later pass because an oxide layer formed on the rod surface. There was no clear evidence of better impurity movement at the slower zone refining speed. Also, constant or variable coil power appeared to have no effect on impurity movement during a single run (10 passes). This experiment was the first step to developing a zone refining process for plutonium metal.

  12. Nuclear electric propulsion for planetary science missions: NASA technology program planning

    NASA Technical Reports Server (NTRS)

    Doherty, Michael P.

    1993-01-01

    This paper presents the status of technology program planning to develop those Nuclear Electric Propulsion technologies needed to meet the advanced propulsion system requirements for planetary science missions in the next century. The technology program planning is based upon technologies with significant development heritage: ion electric propulsion and the SP-100 space nuclear power technologies. Detailed plans are presented for the required ion electric propulsion technology development and demonstration. Closer coordination between space nuclear power and space electric propulsion technology programs is a necessity as technology plans are being further refined in light of NEP concept definition and possible early NEP flight activities.

  13. Ideal Downward Refinement in the EL Description Logic

    NASA Astrophysics Data System (ADS)

    Lehmann, Jens; Haase, Christoph

    With the proliferation of the Semantic Web, there has been a rapidly rising interest in description logics, which form the logical foundation of the W3C standard ontology language OWL. While the number of OWL knowledge bases grows, there is an increasing demand for tools assisting knowledge engineers in building up and maintaining their structure. For this purpose, concept learning algorithms based on refinement operators have been investigated. In this paper, we provide an ideal refinement operator for the description logic EL and show that it is computationally feasible on large knowledge bases.

  14. Bauxite Mining and Alumina Refining

    PubMed Central

    Frisch, Neale; Olney, David

    2014-01-01

    Objective: To describe bauxite mining and alumina refining processes and to outline the relevant physical, chemical, biological, ergonomic, and psychosocial health risks. Methods: Review article. Results: The most important risks relate to noise, ergonomics, trauma, and caustic soda splashes of the skin/eyes. Other risks of note relate to fatigue, heat, and solar ultraviolet and for some operations tropical diseases, venomous/dangerous animals, and remote locations. Exposures to bauxite dust, alumina dust, and caustic mist in contemporary best-practice bauxite mining and alumina refining operations have not been demonstrated to be associated with clinically significant decrements in lung function. Exposures to bauxite dust and alumina dust at such operations are also not associated with the incidence of cancer. Conclusions: A range of occupational health risks in bauxite mining and alumina refining require the maintenance of effective control measures. PMID:24806720

  15. The Empathy Cycle: Refinement of a Nuclear Concept.

    ERIC Educational Resources Information Center

    Barrett-Lennard, G.T.

    1981-01-01

    Delineates a sequence of distinct stages involved in empathic interaction. There is room for considerable slippage between the inner resonation, communication, and reception levels, and measures based on data from different phases would at best be moderately associated. Principal existing (state) scales are located in reference to the model.…

  16. Refining the Instructional Systems Concept: Some Experiences from Military Training.

    ERIC Educational Resources Information Center

    Renckly, Thomas

    1980-01-01

    The systems approach to instruction is studied through an analysis of the use of this approach by the U.S. Air Force's Air Training Command. An explanation of the USAF Instructional Systems Development (ISD) model is given. (RAO)

  17. Multigrid for locally refined meshes

    SciTech Connect

    Shapira, Y.

    1999-12-01

    A multilevel method for the solution of finite element schemes on locally refined meshes is introduced. For isotropic diffusion problems, the condition number of the two-level method is bounded independently of the mesh size and the discontinuities in the diffusion coefficient. The curves of discontinuity need not be aligned with the coarse mesh. Indeed, numerical applications with 10 levels of local refinement yield a rapid convergence of the corresponding 10-level, multigrid V-cycle and other multigrid cycles which are more suitable for parallelism even when the discontinuities are invisible on most of the coarse meshes.

  18. Conformal refinement of unstructured quadrilateral meshes

    SciTech Connect

    Garmella, Rao

    2009-01-01

    We present a multilevel adaptive refinement technique for unstructured quadrilateral meshes in which the mesh is kept conformal at all times. This means that the refined mesh, like the original, is formed of only quadrilateral elements that intersect strictly along edges or at vertices, i.e., vertices of one quadrilateral element do not lie in an edge of another quadrilateral. Elements are refined using templates based on 1:3 refinement of edges. We demonstrate that by careful design of the refinement and coarsening strategy, we can maintain high quality elements in the refined mesh. We demonstrate the method on a number of examples with dynamically changing refinement regions.

  19. Fully implicit adaptive mesh refinement MHD algorithm

    NASA Astrophysics Data System (ADS)

    Philip, Bobby

    2005-10-01

    In the macroscopic simulation of plasmas, the numerical modeler is faced with the challenge of dealing with multiple time and length scales. The former results in stiffness due to the presence of very fast waves. The latter requires one to resolve the localized features that the system develops. Traditional approaches based on explicit time integration techniques and fixed meshes are not suitable for this challenge, as such approaches prevent the modeler from using realistic plasma parameters to keep the computation feasible. We propose here a novel approach, based on implicit methods and structured adaptive mesh refinement (SAMR). Our emphasis is on both accuracy and scalability with the number of degrees of freedom. To our knowledge, a scalable, fully implicit AMR algorithm has not been accomplished before for MHD. As a proof-of-principle, we focus on the reduced resistive MHD model as a basic MHD model paradigm, which is truly multiscale. The approach taken here is to adapt mature physics-based technologyootnotetextL. Chac'on et al., J. Comput. Phys. 178 (1), 15- 36 (2002) to AMR grids, and employ AMR-aware multilevel techniques (such as fast adaptive composite --FAC-- algorithms) for scalability. We will demonstrate that the concept is indeed feasible, featuring optimal scalability under grid refinement. Results of fully-implicit, dynamically-adaptive AMR simulations will be presented on a variety of problems.

  20. Method for refining contaminated iridium

    DOEpatents

    Heshmatpour, B.; Heestand, R.L.

    1982-08-31

    Contaminated iridium is refined by alloying it with an alloying agent selected from the group consisting of manganese and an alloy of manganese and copper, and then dissolving the alloying agent from the formed alloy to provide a purified iridium powder.

  1. Method for refining contaminated iridium

    DOEpatents

    Heshmatpour, Bahman; Heestand, Richard L.

    1983-01-01

    Contaminated iridium is refined by alloying it with an alloying agent selected from the group consisting of manganese and an alloy of manganese and copper, and then dissolving the alloying agent from the formed alloy to provide a purified iridium powder.

  2. Multigrid for refined triangle meshes

    SciTech Connect

    Shapira, Yair

    1997-02-01

    A two-level preconditioning method for the solution of (locally) refined finite element schemes using triangle meshes is introduced. In the isotropic SPD case, it is shown that the condition number of the preconditioned stiffness matrix is bounded uniformly for all sufficiently regular triangulations. This is also verified numerically for an isotropic diffusion problem with highly discontinuous coefficients.

  3. Vacuum Refining of Molten Silicon

    NASA Astrophysics Data System (ADS)

    Safarian, Jafar; Tangstad, Merete

    2012-12-01

    Metallurgical fundamentals for vacuum refining of molten silicon and the behavior of different impurities in this process are studied. A novel mass transfer model for the removal of volatile impurities from silicon in vacuum induction refining is developed. The boundary conditions for vacuum refining system—the equilibrium partial pressures of the dissolved elements and their actual partial pressures under vacuum—are determined through thermodynamic and kinetic approaches. It is indicated that the vacuum removal kinetics of the impurities is different, and it is controlled by one, two, or all the three subsequent reaction mechanisms—mass transfer in a melt boundary layer, chemical evaporation on the melt surface, and mass transfer in the gas phase. Vacuum refining experimental results of this study and literature data are used to study the model validation. The model provides reliable results and shows correlation with the experimental data for many volatile elements. Kinetics of phosphorus removal, which is an important impurity in the production of solar grade silicon, is properly predicted by the model, and it is observed that phosphorus elimination from silicon is significantly increased with increasing process temperature.

  4. GRAIN REFINEMENT OF URANIUM BILLETS

    DOEpatents

    Lewis, L.

    1964-02-25

    A method of refining the grain structure of massive uranium billets without resort to forging is described. The method consists in the steps of beta- quenching the billets, annealing the quenched billets in the upper alpha temperature range, and extrusion upset of the billets to an extent sufficient to increase the cross sectional area by at least 5 per cent. (AEC)

  5. Construction and Application of a Refined Hospital Management Chain.

    PubMed

    Lihua, Yi

    2016-01-01

    Large scale development was quite common in the later period of hospital industrialization in China. Today, Chinese hospital management faces such problems as service inefficiency, high human resources cost, and low rate of capital use. This study analyzes the refined management chain of Wuxi No.2 People's Hospital. This consists of six gears namely, "organizational structure, clinical practice, outpatient service, medical technology, and nursing care and logistics." The gears are based on "flat management system targets, chief of medical staff, centralized outpatient service, intensified medical examinations, vertical nursing management and socialized logistics." The core concepts of refined hospital management are optimizing flow process, reducing waste, improving efficiency, saving costs, and taking good care of patients as most important. Keywords: Hospital, Refined, Management chain PMID:27180468

  6. 40 CFR 80.235 - How does a refiner obtain approval as a small refiner?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... a small refiner? 80.235 Section 80.235 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Provisions § 80.235 How does a refiner obtain approval as a small refiner? (a) Applications for small refiner....225(d), which must be submitted by June 1, 2002. (b) Applications for small refiner status must...

  7. 40 CFR 80.235 - How does a refiner obtain approval as a small refiner?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... a small refiner? 80.235 Section 80.235 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Provisions § 80.235 How does a refiner obtain approval as a small refiner? (a) Applications for small refiner....225(d), which must be submitted by June 1, 2002. (b) Applications for small refiner status must...

  8. Technology Alignment and Portfolio Prioritization (TAPP): Advanced Methods in Strategic Analysis, Technology Forecasting and Long Term Planning for Human Exploration and Operations, Advanced Exploration Systems and Advanced Concepts

    NASA Technical Reports Server (NTRS)

    Funaro, Gregory V.; Alexander, Reginald A.

    2015-01-01

    The Advanced Concepts Office (ACO) at NASA, Marshall Space Flight Center is expanding its current technology assessment methodologies. ACO is developing a framework called TAPP that uses a variety of methods, such as association mining and rule learning from data mining, structure development using a Technological Innovation System (TIS), and social network modeling to measure structural relationships. The role of ACO is to 1) produce a broad spectrum of ideas and alternatives for a variety of NASA's missions, 2) determine mission architecture feasibility and appropriateness to NASA's strategic plans, and 3) define a project in enough detail to establish an initial baseline capable of meeting mission objectives ACO's role supports the decision­-making process associated with the maturation of concepts for traveling through, living in, and understanding space. ACO performs concept studies and technology assessments to determine the degree of alignment between mission objectives and new technologies. The first step in technology assessment is to identify the current technology maturity in terms of a technology readiness level (TRL). The second step is to determine the difficulty associated with advancing a technology from one state to the next state. NASA has used TRLs since 1970 and ACO formalized them in 1995. The DoD, ESA, Oil & Gas, and DoE have adopted TRLs as a means to assess technology maturity. However, "with the emergence of more complex systems and system of systems, it has been increasingly recognized that TRL assessments have limitations, especially when considering [the] integration of complex systems." When performing the second step in a technology assessment, NASA requires that an Advancement Degree of Difficulty (AD2) method be utilized. NASA has used and developed or used a variety of methods to perform this step: Expert Opinion or Delphi Approach, Value Engineering or Value Stream, Analytical Hierarchy Process (AHP), Technique for the Order of

  9. Personnel Development. A Plan to Produce and Distribute an Instructional Package for Teaching the Concepts of Competency-Based Instruction in Home Economics Pre-service Teacher Education Programs. Final Report.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg.

    Described in this final report is the development of a plan to produce and distribute an instructional package for teaching the concepts of competency-based instruction in home economics pre-service education programs in the state of Virginia. Nine Virginia Universities (Virginia Polytechnic Institution and State University, Radford College, James…

  10. Parallel Adaptive Mesh Refinement Library

    NASA Technical Reports Server (NTRS)

    Mac-Neice, Peter; Olson, Kevin

    2005-01-01

    Parallel Adaptive Mesh Refinement Library (PARAMESH) is a package of Fortran 90 subroutines designed to provide a computer programmer with an easy route to extension of (1) a previously written serial code that uses a logically Cartesian structured mesh into (2) a parallel code with adaptive mesh refinement (AMR). Alternatively, in its simplest use, and with minimal effort, PARAMESH can operate as a domain-decomposition tool for users who want to parallelize their serial codes but who do not wish to utilize adaptivity. The package builds a hierarchy of sub-grids to cover the computational domain of a given application program, with spatial resolution varying to satisfy the demands of the application. The sub-grid blocks form the nodes of a tree data structure (a quad-tree in two or an oct-tree in three dimensions). Each grid block has a logically Cartesian mesh. The package supports one-, two- and three-dimensional models.

  11. Entitlements exemptions for new refiners

    SciTech Connect

    Not Available

    1980-02-29

    The practice of exempting start-up inventories from entitlement requirements for new refiners has been called into question by the Office of Hearings and Appeals and other responsible Departmental officials. ERA with the assistance of the Office of General Counsel considering resolving the matter through rulemaking; however, by October 26, 1979 no rulemaking had been published. Because of the absence of published standards for use in granting these entitlements to new refineries, undue reliance was placed on individual judgements that could result in inequities to applicants and increase the potential for fraud and abuse. Recommendations are given as follows: (1) if the program for granting entitlements exemptions to new refiners is continued, the Administrator, ERA should promptly take action to adopt an appropriate regulation to formalize the program by establishing standards and controls that will assure consistent and equitable application; in addition, files containing adjustments given to new refiners should be made complete to support benefits already allowed; and (2) whether the program is continued or discontinued, the General Counsel and the Administrator, ERA, should coordiate on how to evaluate the propriety of inventory adjustments previously granted to new refineries.

  12. Reformulated Gasoline Market Affected Refiners Differently, 1995

    EIA Publications

    1996-01-01

    This article focuses on the costs of producing reformulated gasoline (RFG) as experienced by different types of refiners and on how these refiners fared this past summer, given the prices for RFG at the refinery gate.

  13. A Refined Cauchy-Schwarz Inequality

    ERIC Educational Resources Information Center

    Mercer, Peter R.

    2007-01-01

    The author presents a refinement of the Cauchy-Schwarz inequality. He shows his computations in which refinements of the triangle inequality and its reverse inequality are obtained for nonzero x and y in a normed linear space.

  14. Firing of pulverized solvent refined coal

    DOEpatents

    Derbidge, T. Craig; Mulholland, James A.; Foster, Edward P.

    1986-01-01

    An air-purged burner for the firing of pulverized solvent refined coal is constructed and operated such that the solvent refined coal can be fired without the coking thereof on the burner components. The air-purged burner is designed for the firing of pulverized solvent refined coal in a tangentially fired boiler.

  15. Grain Refinement of Deoxidized Copper

    NASA Astrophysics Data System (ADS)

    Balart, María José; Patel, Jayesh B.; Gao, Feng; Fan, Zhongyun

    2016-08-01

    This study reports the current status of grain refinement of copper accompanied in particular by a critical appraisal of grain refinement of phosphorus-deoxidized, high residual P (DHP) copper microalloyed with 150 ppm Ag. Some deviations exist in terms of the growth restriction factor (Q) framework, on the basis of empirical evidence reported in the literature for grain size measurements of copper with individual additions of 0.05, 0.1, and 0.5 wt pct of Mo, In, Sn, Bi, Sb, Pb, and Se, cast under a protective atmosphere of pure Ar and water quenching. The columnar-to-equiaxed transition (CET) has been observed in copper, with an individual addition of 0.4B and with combined additions of 0.4Zr-0.04P and 0.4Zr-0.04P-0.015Ag and, in a previous study, with combined additions of 0.1Ag-0.069P (in wt pct). CETs in these B- and Zr-treated casts have been ascribed to changes in the morphology and chemistry of particles, concurrently in association with free solute type and availability. No further grain-refining action was observed due to microalloying additions of B, Mg, Ca, Zr, Ti, Mn, In, Fe, and Zn (~0.1 wt pct) with respect to DHP-Cu microalloyed with Ag, and therefore are no longer relevant for the casting conditions studied. The critical microalloying element for grain size control in deoxidized copper and in particular DHP-Cu is Ag.

  16. Risk-based system refinement

    SciTech Connect

    Winter, V.L.; Berg, R.S.; Dalton, L.J.

    1998-06-01

    When designing a high consequence system, considerable care should be taken to ensure that the system can not easily be placed into a high consequence failure state. A formal system design process should include a model that explicitly shows the complete state space of the system (including failure states) as well as those events (e.g., abnormal environmental conditions, component failures, etc.) that can cause a system to enter a failure state. In this paper the authors present such a model and formally develop a notion of risk-based refinement with respect to the model.

  17. Solvent refined coal (SRC) process

    SciTech Connect

    Not Available

    1980-12-01

    This report summarizes the progress of the Solvent Refined Coal (SRC) project by The Pittsburg and Midway Coal Mining Co. at the SRC Pilot Plant in Fort Lewis, Washington and the Gulf Science and Technology Company Process Development Unit (P-99) in Harmarville, Pennsylvania, for the Department of Energy during the month of October, 1980. The Fort Lewis Pilot Plant was shut down the entire month of October, 1980 for inspection and maintenance. PDU P-99 completed two runs during October investigating potential start-up modes for the Demonstration Plant.

  18. Consumers' salient beliefs regarding dairy products in the functional food era: a qualitative study using concepts from the theory of planned behaviour

    PubMed Central

    2011-01-01

    Background Inadequate consumption of dairy products without appropriate dietary substitution may have deleterious health consequences. Social research reveals the factors that may impede compliance with dietary recommendations. This is particularly important given the recent introduction of functional dairy products. One of the challenges for public health professionals is to demonstrate the efficacy of nutrition education in improving attitudes toward nutrient rich foods. The aim of this study was to explore the salient beliefs of adult weight loss trial participants regarding both traditional and functional dairy products and to compare these with a control group not exposed to nutrition education. Methods Six focus groups were conducted, three with weight loss trial completers (n = 15) that had received nutrition education and three with individuals from the same region (n = 14) to act as controls. Transcribed focus groups were coded using the Theory of Planned Behaviour theoretical framework. Results Non-trial participants perceived dairy foods as weight inducing and were sceptical of functional dairy products. A lack of time/ability to decipher dairy food labels was also discussed by these individuals. In contrast trial participants discussed several health benefits related to dairy foods, practised label reading and were confident in their ability to incorporate dairy foods into their diet. Normative beliefs expressed were similar for both groups indicating that these were more static and less amenable to change through nutrition education than control and behavioural beliefs. Conclusions Nutrition education provided as a result of weight loss trial participation influenced behavioural and control beliefs relating to dairy products. This study provides a proof of concept indication that nutrition education may improve attitudes towards dairy products and may thus be an important target for public health campaigns seeking to increase intake of this food group

  19. 40 CFR 80.1340 - How does a refiner obtain approval as a small refiner?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... a small refiner? 80.1340 Section 80.1340 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Small Refiner Provisions § 80.1340 How does a refiner obtain approval as a small refiner? (a) Applications for...

  20. 40 CFR 80.1340 - How does a refiner obtain approval as a small refiner?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... a small refiner? 80.1340 Section 80.1340 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Small Refiner Provisions § 80.1340 How does a refiner obtain approval as a small refiner? (a) Applications for...

  1. Materials refining on the Moon

    NASA Astrophysics Data System (ADS)

    Landis, Geoffrey A.

    2007-05-01

    Oxygen, metals, silicon, and glass are raw materials that will be required for long-term habitation and production of structural materials and solar arrays on the Moon. A process sequence is proposed for refining these materials from lunar regolith, consisting of separating the required materials from lunar rock with fluorine. The fluorine is brought to the Moon in the form of potassium fluoride, and is liberated from the salt by electrolysis in a eutectic salt melt. Tetrafluorosilane produced by this process is reduced to silicon by a plasma reduction stage; the fluorine salts are reduced to metals by reaction with metallic potassium. Fluorine is recovered from residual MgF and CaF2 by reaction with K2O.

  2. Adaptive mesh refinement in titanium

    SciTech Connect

    Colella, Phillip; Wen, Tong

    2005-01-21

    In this paper, we evaluate Titanium's usability as a high-level parallel programming language through a case study, where we implement a subset of Chombo's functionality in Titanium. Chombo is a software package applying the Adaptive Mesh Refinement methodology to numerical Partial Differential Equations at the production level. In Chombo, the library approach is used to parallel programming (C++ and Fortran, with MPI), whereas Titanium is a Java dialect designed for high-performance scientific computing. The performance of our implementation is studied and compared with that of Chombo in solving Poisson's equation based on two grid configurations from a real application. Also provided are the counts of lines of code from both sides.

  3. Algorithm refinement for fluctuating hydrodynamics

    SciTech Connect

    Williams, Sarah A.; Bell, John B.; Garcia, Alejandro L.

    2007-07-03

    This paper introduces an adaptive mesh and algorithmrefinement method for fluctuating hydrodynamics. This particle-continuumhybrid simulates the dynamics of a compressible fluid with thermalfluctuations. The particle algorithm is direct simulation Monte Carlo(DSMC), a molecular-level scheme based on the Boltzmann equation. Thecontinuum algorithm is based on the Landau-Lifshitz Navier-Stokes (LLNS)equations, which incorporate thermal fluctuations into macroscopichydrodynamics by using stochastic fluxes. It uses a recently-developedsolver for LLNS, based on third-order Runge-Kutta. We present numericaltests of systems in and out of equilibrium, including time-dependentsystems, and demonstrate dynamic adaptive refinement by the computationof a moving shock wave. Mean system behavior and second moment statisticsof our simulations match theoretical values and benchmarks well. We findthat particular attention should be paid to the spectrum of the flux atthe interface between the particle and continuum methods, specificallyfor the non-hydrodynamic (kinetic) time scales.

  4. A novel application of theory refinement to student modeling

    SciTech Connect

    Baffes, P.T.; Mooney, R.J.

    1996-12-31

    Theory refinement systems developed in machine learning automatically modify a knowledge base to render it consistent with a set of classified training examples. We illustrate a novel application of these techniques to the problem of constructing a student model for an intelligent tutoring system (ITS). Our approach is implemented in an ITS authoring system called ASSERT which uses theory refinement to introduce errors into an initially correct knowledge base so that it models incorrect student behavior. The efficacy of the approach has been demonstrated by evaluating a tutor developed with ASSERT with 75 students tested on a classification task covering concepts from an introductory course on the C{sup ++} programming language. The system produced reasonably accurate models and students who received feedback based on these models performed significantly better on a post test than students who received simple reteaching.

  5. Concept Formation.

    ERIC Educational Resources Information Center

    Vaidya, Narendera

    This document, published in India by the Regional College of Education, deals with 13 subjects: the tough context (thinking), definitions of concept, functions of concept, the process of concept formation, discriminant learning, mediation process, second signalling system, factors affecting concept formation, studies in concept formation, the…

  6. Silicon refinement by chemical vapor transport

    NASA Technical Reports Server (NTRS)

    Olson, J.

    1984-01-01

    Silicon refinement by chemical vapor transport is discussed. The operating characteristics of the purification process, including factors affecting the rate, purification efficiency and photovoltaic quality of the refined silicon were studied. The casting of large alloy plates was accomplished. A larger research scale reactor is characterized, and it is shown that a refined silicon product yields solar cells with near state of the art conversion efficiencies.

  7. Refining the shallow slip deficit

    NASA Astrophysics Data System (ADS)

    Xu, Xiaohua; Tong, Xiaopeng; Sandwell, David T.; Milliner, Christopher W. D.; Dolan, James F.; Hollingsworth, James; Leprince, Sebastien; Ayoub, Francois

    2016-03-01

    Geodetic slip inversions for three major (Mw > 7) strike-slip earthquakes (1992 Landers, 1999 Hector Mine and 2010 El Mayor-Cucapah) show a 15-60 per cent reduction in slip near the surface (depth < 2 km) relative to the slip at deeper depths (4-6 km). This significant difference between surface coseismic slip and slip at depth has been termed the shallow slip deficit (SSD). The large magnitude of this deficit has been an enigma since it cannot be explained by shallow creep during the interseismic period or by triggered slip from nearby earthquakes. One potential explanation for the SSD is that the previous geodetic inversions lack data coverage close to surface rupture such that the shallow portions of the slip models are poorly resolved and generally underestimated. In this study, we improve the static coseismic slip inversion for these three earthquakes, especially at shallow depths, by: (1) including data capturing the near-fault deformation from optical imagery and SAR azimuth offsets; (2) refining the interferometric synthetic aperture radar processing with non-boxcar phase filtering, model-dependent range corrections, more complete phase unwrapping by SNAPHU (Statistical Non-linear Approach for Phase Unwrapping) assuming a maximum discontinuity and an on-fault correlation mask; (3) using more detailed, geologically constrained fault geometries and (4) incorporating additional campaign global positioning system (GPS) data. The refined slip models result in much smaller SSDs of 3-19 per cent. We suspect that the remaining minor SSD for these earthquakes likely reflects a combination of our elastic model's inability to fully account for near-surface deformation, which will render our estimates of shallow slip minima, and potentially small amounts of interseismic fault creep or triggered slip, which could `make up' a small percentages of the coseismic SSD during the interseismic period. Our results indicate that it is imperative that slip inversions include

  8. Facade model refinement by fusing terrestrial laser data and image

    NASA Astrophysics Data System (ADS)

    Liu, Yawen; Qin, Sushun

    2015-12-01

    The building facade model is one of main landscapes of a city and basic data of city geographic information. It is widely useful in accurate path planning, real navigation through the urban environment, location-based application, etc. In this paper, a method of facade model refinement by fusing terrestrial laser data and image is presented. It uses the matching of model edge and image line combined with laser data verification and effectively refines facade geometry model that reconstructed from laser data. The laser data of geometric structures on building facade such as window, balcony and door are segmented, and used as a constraint for further selecting the optical model edges that are located at the cross-line of point data and no data. The results demonstrate the deviation of model edges caused by laser sampling interval can be removed in the proposed method.

  9. Teachers' Conceptions of Tangent Line

    ERIC Educational Resources Information Center

    Paez Murillo, Rosa Elvira; Vivier, Laurent

    2013-01-01

    In order to study the conceptions, and their evolutions, of the tangent line to a curve an updating workshop which took place in Mexico was designed for upper secondary school teachers. This workshop was planned using the methodology of cooperative learning, scientific debate and auto reflection (ACODESA) and the conception-knowing-concept model…

  10. Adaptive Mesh Refinement for Microelectronic Device Design

    NASA Technical Reports Server (NTRS)

    Cwik, Tom; Lou, John; Norton, Charles

    1999-01-01

    Finite element and finite volume methods are used in a variety of design simulations when it is necessary to compute fields throughout regions that contain varying materials or geometry. Convergence of the simulation can be assessed by uniformly increasing the mesh density until an observable quantity stabilizes. Depending on the electrical size of the problem, uniform refinement of the mesh may be computationally infeasible due to memory limitations. Similarly, depending on the geometric complexity of the object being modeled, uniform refinement can be inefficient since regions that do not need refinement add to the computational expense. In either case, convergence to the correct (measured) solution is not guaranteed. Adaptive mesh refinement methods attempt to selectively refine the region of the mesh that is estimated to contain proportionally higher solution errors. The refinement may be obtained by decreasing the element size (h-refinement), by increasing the order of the element (p-refinement) or by a combination of the two (h-p refinement). A successful adaptive strategy refines the mesh to produce an accurate solution measured against the correct fields without undue computational expense. This is accomplished by the use of a) reliable a posteriori error estimates, b) hierarchal elements, and c) automatic adaptive mesh generation. Adaptive methods are also useful when problems with multi-scale field variations are encountered. These occur in active electronic devices that have thin doped layers and also when mixed physics is used in the calculation. The mesh needs to be fine at and near the thin layer to capture rapid field or charge variations, but can coarsen away from these layers where field variations smoothen and charge densities are uniform. This poster will present an adaptive mesh refinement package that runs on parallel computers and is applied to specific microelectronic device simulations. Passive sensors that operate in the infrared portion of

  11. Automated knowledge-base refinement

    NASA Technical Reports Server (NTRS)

    Mooney, Raymond J.

    1994-01-01

    Over the last several years, we have developed several systems for automatically refining incomplete and incorrect knowledge bases. These systems are given an imperfect rule base and a set of training examples and minimally modify the knowledge base to make it consistent with the examples. One of our most recent systems, FORTE, revises first-order Horn-clause knowledge bases. This system can be viewed as automatically debugging Prolog programs based on examples of correct and incorrect I/O pairs. In fact, we have already used the system to debug simple Prolog programs written by students in a programming language course. FORTE has also been used to automatically induce and revise qualitative models of several continuous dynamic devices from qualitative behavior traces. For example, it has been used to induce and revise a qualitative model of a portion of the Reaction Control System (RCS) of the NASA Space Shuttle. By fitting a correct model of this portion of the RCS to simulated qualitative data from a faulty system, FORTE was also able to correctly diagnose simple faults in this system.

  12. Pneumatic conveying of pulverized solvent refined coal

    DOEpatents

    Lennon, Dennis R.

    1984-11-06

    A method for pneumatically conveying solvent refined coal to a burner under conditions of dilute phase pneumatic flow so as to prevent saltation of the solvent refined coal in the transport line by maintaining the transport fluid velocity above approximately 95 ft/sec.

  13. Anomalies in the refinement of isoleucine

    SciTech Connect

    Berntsen, Karen R. M.; Vriend, Gert

    2014-04-01

    The side-chain torsion angles of isoleucines in X-ray protein structures are a function of resolution, secondary structure and refinement software. Detailing the standard torsion angles used in refinement software can improve protein structure refinement. A study of isoleucines in protein structures solved using X-ray crystallography revealed a series of systematic trends for the two side-chain torsion angles χ{sub 1} and χ{sub 2} dependent on the resolution, secondary structure and refinement software used. The average torsion angles for the nine rotamers were similar in high-resolution structures solved using either the REFMAC, CNS or PHENIX software. However, at low resolution these programs often refine towards somewhat different χ{sub 1} and χ{sub 2} values. Small systematic differences can be observed between refinement software that uses molecular dynamics-type energy terms (for example CNS) and software that does not use these terms (for example REFMAC). Detailing the standard torsion angles used in refinement software can improve the refinement of protein structures. The target values in the molecular dynamics-type energy functions can also be improved.

  14. Concept Mapping

    PubMed Central

    Brennan, Laura K.; Brownson, Ross C.; Kelly, Cheryl; Ivey, Melissa K.; Leviton, Laura C.

    2016-01-01

    Background From 2003 to 2008, 25 cross-sector, multidisciplinary community partnerships funded through the Active Living by Design (ALbD) national program designed, planned, and implemented policy and environmental changes, with complementary programs and promotions. This paper describes the use of concept-mapping methods to gain insights into promising active living intervention strategies based on the collective experience of community representatives implementing ALbD initiatives. Methods Using Concept Systems software, community representatives (n=43) anonymously generated actions and changes in their communities to support active living (183 original statements, 79 condensed statements). Next, respondents (n=26, from 23 partnerships) sorted the 79 statements into self-created categories, or active living intervention approaches. Respondents then rated statements based on their perceptions of the most important strategies for creating community changes (n=25, from 22 partnerships) and increasing community rates of physical activity (n=23, from 20 partnerships). Cluster analysis and multidimensional scaling were used to describe data patterns. Results ALbD community partnerships identified three active living intervention approaches with the greatest perceived importance to create community change and increase population levels of physical activity: changes to the built and natural environment, partnership and collaboration efforts, and land-use and transportation policies. The relative importance of intervention approaches varied according to subgroups of partnerships working with different populations. Conclusions Decision makers, practitioners, and community residents can incorporate what has been learned from the 25 community partnerships to prioritize active living policy, physical project, promotional, and programmatic strategies for work in different populations and settings. PMID:23079266

  15. Anomalies in the refinement of isoleucine

    PubMed Central

    Berntsen, Karen R. M.; Vriend, Gert

    2014-01-01

    A study of isoleucines in protein structures solved using X-ray crystallography revealed a series of systematic trends for the two side-chain torsion angles χ1 and χ2 dependent on the resolution, secondary structure and refinement software used. The average torsion angles for the nine rotamers were similar in high-resolution structures solved using either the REFMAC, CNS or PHENIX software. However, at low resolution these programs often refine towards somewhat different χ1 and χ2 values. Small systematic differences can be observed between refinement software that uses molecular dynamics-type energy terms (for example CNS) and software that does not use these terms (for example REFMAC). Detailing the standard torsion angles used in refinement software can improve the refinement of protein structures. The target values in the molecular dynamics-type energy functions can also be improved. PMID:24699648

  16. Advanced space system concepts and their orbital support needs (1980 - 2000). Volume 4: Detailed data. Part 2: Program plans and common support needs (a study of the commonality of space vehicle applications to future national needs

    NASA Technical Reports Server (NTRS)

    Bekey, I.; Mayer, H. L.; Wolfe, M. G.

    1976-01-01

    The methodology of alternate world future scenarios is utilized for selecting a plausible, though not advocated, set of future scenarios each of which results in a program plan appropriate for the respective environment. Each such program plan gives rise to different building block and technology requirements, which are analyzed for common need between the NASA and the DoD for each of the alternate world scenarios. An essentially invariant set of system, building block, and technology development plans is presented at the conclusion, intended to allow protection of most of the options for system concepts regardless of what the actual future world environment turns out to be. Thus, building block and technology needs are derived which support: (1) each specific world scenario; (2) all the world scenarios identified in this study; or (3) generalized scenarios applicable to almost any future environment. The output included in this volume consists of the building blocks, i.e.: transportation vehicles, orbital support vehicles, and orbital support facilities; the technology required to support the program plans; identification of their features which could support the DoD and NASA in common; and a complete discussion of the planning methodology.

  17. Refinement of boards' role required.

    PubMed

    Umbdenstock, R J

    1987-01-01

    The governing board's role in health care is not changing, but new competitive forces necessitate a refinement of the board's approach to fulfilling its role. In a free-standing, community, not-for-profit hospital, the board functions as though it were the "owner." Although it does not truly own the facility in the legal sense, the board does have legal, fiduciary, and financial responsibilities conferred on it by the state. In a religious-sponsored facility, the board fulfills these same obligations on behalf of the sponsoring institute, subject to the institute's reserved powers. In multi-institutional systems, the hospital board's power and authority depend on the role granted it by the system. Boards in all types of facilities are currently faced with the following challenges: Fulfilling their basic responsibilities, such as legal requirements, financial duties, and obligations for the quality of care. Encouraging management and the board itself to "think strategically" in attacking new competitive market forces while protecting the organization's traditional mission and values. Assessing recommended strategies in light of consequences if constituencies think the organization is abandoning its commitments. Boards can take several steps to match their mode of operation with the challenges of the new environment. Boards must rededicate themselves to the hospital's mission. Trustees must expand their understanding of health care trends and issues and their effect on the organization. Boards must evaluate and help strengthen management's performance, rather than acting as a "watchdog" in an adversarial position. Boards must think strategically, rather than focusing solely on operational details. Boards must evaluate the methods they use for conducting business. PMID:10280356

  18. North Dakota Refining Capacity Study

    SciTech Connect

    Dennis Hill; Kurt Swenson; Carl Tuura; Jim Simon; Robert Vermette; Gilberto Marcha; Steve Kelly; David Wells; Ed Palmer; Kuo Yu; Tram Nguyen; Juliam Migliavacca

    2011-01-05

    According to a 2008 report issued by the United States Geological Survey, North Dakota and Montana have an estimated 3.0 to 4.3 billion barrels of undiscovered, technically recoverable oil in an area known as the Bakken Formation. With the size and remoteness of the discovery, the question became 'can a business case be made for increasing refining capacity in North Dakota?' And, if so what is the impact to existing players in the region. To answer the question, a study committee comprised of leaders in the region's petroleum industry were brought together to define the scope of the study, hire a consulting firm and oversee the study. The study committee met frequently to provide input on the findings and modify the course of the study, as needed. The study concluded that the Petroleum Area Defense District II (PADD II) has an oversupply of gasoline. With that in mind, a niche market, naphtha, was identified. Naphtha is used as a diluent used for pipelining the bitumen (heavy crude) from Canada to crude markets. The study predicted there will continue to be an increase in the demand for naphtha through 2030. The study estimated the optimal configuration for the refinery at 34,000 barrels per day (BPD) producing 15,000 BPD of naphtha and a 52 percent refinery charge for jet and diesel yield. The financial modeling assumed the sponsor of a refinery would invest its own capital to pay for construction costs. With this assumption, the internal rate of return is 9.2 percent which is not sufficient to attract traditional investment given the risk factor of the project. With that in mind, those interested in pursuing this niche market will need to identify incentives to improve the rate of return.

  19. Space transfer concepts and analysis for exploration missions. Implementation plan and element description document. Volume 1: Major trades. Book 1: Draft final

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This document presents trade studies and reference concept designs accomplished during a study of Space Transfer Concepts and Analyses for Exploration Missions (STCAEM). This volume contains the major top level trades, level 2 trades conducted in support of NASA's Lunar/Mars Exploration Program Office, and a synopsis of the vehicles for different propulsion systems under trade consideration. The vehicles are presented in more detail in other volumes of this report. Book 1 of Volume 1 covers the following analyses: lunar/Mars commonality trades, lunar/Mars mission operations, and Mars transfer systems.

  20. Planned orphanhood.

    PubMed

    Landau, R

    1999-07-01

    Medical technology, which today makes it possible to bear a child after death, enables planned orphanhood. The first part of this paper will discuss the medical innovations in human conception, the psycho-social aspects of the wish for children from the genes of someone who is no longer alive, and the ensuing orphanhood and its implications. The second part will discuss the ethical issues relating to planned orphanhood: Who are involved in the matter of planned orphanhood? Is the decision to produce a planned orphan a private or public matter? Whose responsibility is the birth and bringing up of the planned orphan? To whom does society have more responsibility - the children who already exist or future children? And can planned orphanhood be regarded as a justification for wrongful conception? The last part of the paper will examine the judicial aspects of planned orphanhood in Israel and elsewhere and discuss the application of the principles of human dignity, human welfare, and justice. The paper argues for discouraging planned orphanhood so as to avoid violating the principles of human dignity and liberty, human welfare, and human justice, from the perspectives of both those who are involved in the process in general and the orphan who is the target of the medical intervention in particular. Its aim is to encourage deep and comprehensive public discussion of this issue in all its aspects. PMID:10414828

  1. Using a conformation-dependent stereochemical library improves crystallographic refinement of proteins

    SciTech Connect

    Tronrud, Dale E.; Berkholz, Donald S.; Karplus, P. Andrew

    2010-07-02

    The major macromolecular crystallographic refinement packages restrain models to ideal geometry targets defined as single values that are independent of molecular conformation. However, ultrahigh-resolution X-ray models of proteins are not consistent with this concept of ideality and have been used to develop a library of ideal main-chain bond lengths and angles that are parameterized by the {phi}/{psi} angle of the residue [Berkholz et al. (2009), Structure, 17, 1316-1325]. Here, it is first shown that the new conformation-dependent library does not suffer from poor agreement with ultrahigh-resolution structures, whereas current libraries have this problem. Using the TNT refinement package, it is then shown that protein structure refinement using this conformation-dependent library results in models that have much better agreement with library values of bond angles with little change in the R values. These tests support the value of revising refinement software to account for this new paradigm.

  2. A Journey through Time: From the Present Value to the Future Value and Back Or: Retirement Planning: A Comprehensible Application of the Time Value of Money Concept

    ERIC Educational Resources Information Center

    Schmidt, Carolin E.

    2016-01-01

    Real-life applications of financial concepts are a valuable method to get students engaged in financial topics. While especially non-finance majors often struggle to understand the importance of financial topics for their personal lives, applying these theories to real-life examples can significantly improve their learning experience and increase…

  3. Strategies for hp-adaptive Refinement

    SciTech Connect

    Mitchell, William F.

    2008-09-01

    In the hp-adaptive version of the finite element method for solving partial differential equations, the grid is adaptively refined in both h, the size of the elements, and p, the degree of the piecewise polynomial approximation over the element. The selection of which elements to refine is determined by a local a posteriori error indicator, and is well established. But the determination of whether the element should be refined by h or p is still open. In this paper, we describe several strategies that have been proposed for making this determination. A numerical example to illustrate the effectiveness of these strategies will be presented.

  4. Firing of pulverized solvent refined coal

    DOEpatents

    Lennon, Dennis R.; Snedden, Richard B.; Foster, Edward P.; Bellas, George T.

    1990-05-15

    A burner for the firing of pulverized solvent refined coal is constructed and operated such that the solvent refined coal can be fired successfully without any performance limitations and without the coking of the solvent refined coal on the burner components. The burner is provided with a tangential inlet of primary air and pulverized fuel, a vaned diffusion swirler for the mixture of primary air and fuel, a center water-cooled conical diffuser shielding the incoming fuel from the heat radiation from the flame and deflecting the primary air and fuel steam into the secondary air, and a watercooled annulus located between the primary air and secondary air flows.

  5. Space Operations Center: A concept analysis

    NASA Technical Reports Server (NTRS)

    Livingston, L. E.

    1979-01-01

    The Space Operations Center is a concept for a shuttle-service, permanent, manned facility in low Earth orbit. An analysis of this concept was conducted and the results are reported. It is noted that there are no NASA plans at present to implement such a concept. The results are intended for consideration in future planning.

  6. Application of Digital Logic Based on the Concept of Green Building--Taking Xuzhou Fenghua Garden Residential Planning as an Example

    NASA Astrophysics Data System (ADS)

    Feng, J. H.; Zhu, D. D.

    Because the low carbon and sustainable development becomes more and more important in Chinese even in all over the world, author sorted out the logic of green building technology with the logic of digital technology by generalizing the development and type of modern green building technology. As the specific experiment object, Xuzhou Fenghua garden residential district was planned and designed though green digital design means. The reasonable general plan was designed scientifically and efficiently though the immediate colorful chill sunshine time map and repeated adjusted design. The above is to prove the efficiency and possibility of green digital design and bring inspiration to a deeper level of advanced algorithm.

  7. Refining Gold from Existing Data

    PubMed Central

    Wade, Ted D.

    2014-01-01

    Purpose of review The purpose is to review the arguments for increasing use of existing data in health research. Recent Findings The reuse of data in observational, exploratory and outcome studies, as well as in confirming other findings, is being justified on epistemological grounds as the major path to new knowledge and to the generalizing of findings to “real world” populations. It is also justified on grounds of cost, power and efficiency, even though data reuse comes with real informatics, scientific culture, societal and regulatory issues. Summary Data reuse is becoming more compelling. When contemplating new research for any purpose other than RCTs for efficacy, it is prudent to consider whether partnership with existing data holders should be part of the optimal research plan. PMID:24625777

  8. Financial Planning Models: Concepts and Case Studies in Colleges and Universities. Proceedings of a Workshop (Indianapolis, IN, August 27-29, 1978).

    ERIC Educational Resources Information Center

    Wyatt, Joe B., Ed.; And Others

    The development and use of financial planning models, with a focus on the Stanford University financial tradeoff (TRADES) methodology, are covered in conference papers, along with the application of the Stanford conceptual framework in five institutional settings. Additional papers consider an experimental modeling language that was developed to…

  9. Refined Phenotyping of Modic Changes

    PubMed Central

    Määttä, Juhani H.; Karppinen, Jaro; Paananen, Markus; Bow, Cora; Luk, Keith D.K.; Cheung, Kenneth M.C.; Samartzis, Dino

    2016-01-01

    . The strength of the associations increased with the number of MC. This large-scale study is the first to definitively note MC types and specific morphologies to be independently associated with prolonged severe LBP and back-related disability. This proposed refined MC phenotype may have direct implications in clinical decision-making as to the development and management of LBP. Understanding of these imaging biomarkers can lead to new preventative and personalized therapeutics related to LBP. PMID:27258491

  10. Orthogonal polynomials for refinable linear functionals

    NASA Astrophysics Data System (ADS)

    Laurie, Dirk; de Villiers, Johan

    2006-12-01

    A refinable linear functional is one that can be expressed as a convex combination and defined by a finite number of mask coefficients of certain stretched and shifted replicas of itself. The notion generalizes an integral weighted by a refinable function. The key to calculating a Gaussian quadrature formula for such a functional is to find the three-term recursion coefficients for the polynomials orthogonal with respect to that functional. We show how to obtain the recursion coefficients by using only the mask coefficients, and without the aid of modified moments. Our result implies the existence of the corresponding refinable functional whenever the mask coefficients are nonnegative, even when the same mask does not define a refinable function. The algorithm requires O(n^2) rational operations and, thus, can in principle deliver exact results. Numerical evidence suggests that it is also effective in floating-point arithmetic.