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Sample records for condilomatosis vulvoperineal gigante

  1. Vulvoperineal Crohn's disease responsive to metronidazole*

    PubMed Central

    Rosmaninho, Aristóteles; Sanches, Madalena; Salgado, Marta; Alves, Rosário; Selores, Manuela

    2013-01-01

    Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological lesions are the inaugural event and may constitute the only sign of the disease. Vulvoperineal involvement is rare, may precede bowel symptoms by months to years and may go unrecognized. Due to the paucity of reports of Crohn's disease at this location and in the absence of randomized trials, there are no standard treatments for the cutaneous disease. We describe the case of a 47 year-old woman with vulvoperineal Crohn's disease without digestive involvement, that was successfully managed with metronidazole. PMID:24346884

  2. End-Guadalupian extinction of the Permian gigantic bivalve Alatoconchidae: End of gigantism in tropical seas by cooling

    E-print Network

    Ikegami, Takashi

    End-Guadalupian extinction of the Permian gigantic bivalve Alatoconchidae: End of gigantism 2009 Keywords: Gigantism Capitanian Permian Mass extinction photosymbiosis Eutrophication The unique, Verbeekinidae, and Waagenophyllidae) became extinct either during the Late Guadalupian or around the Guadalupian

  3. Dwarfism and gigantism in historical picture postcards.

    PubMed Central

    Enderle, A

    1998-01-01

    A collection of 893 historical picture postcards from 1900 to 1935, depicting dwarfs and giants, was analysed from medical and psychosocial viewpoints. In conditions such as 'bird headed dwarfism', achondroplasia, cretinism, so-called Aztecs or pinheads, Grebe chondrodysplasia, and acromegalic gigantism, the disorder could be diagnosed easily. In hypopituitary dwarfism, exact diagnosis was more difficult because of heterogeneity. The most common conditions depicted were pituitary dwarfism and achondroplasia. Most of those with gigantism had pituitary gigantism and acromegaly. Brothers and sisters or parents and their children provided evidence of mendelian inheritance of some of these disorders. The cards suggest that being put on show provided, at least in some cases, social benefits. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 PMID:9764085

  4. Evolution of gigantism in amphiumid salamanders.

    PubMed

    Bonett, Ronald M; Chippindale, Paul T; Moler, Paul E; Van Devender, R Wayne; Wake, David B

    2009-01-01

    The Amphiumidae contains three species of elongate, permanently aquatic salamanders with four diminutive limbs that append one, two, or three toes. Two of the species, Amphiuma means and A. tridactylum, are among the largest salamanders in the world, reaching lengths of more than one meter, whereas the third species (A. pholeter), extinct amphiumids, and closely related salamander families are relatively small. Amphiuma means and A. tridactylum are widespread species and live in a wide range of lowland aquatic habitats on the Coastal Plain of the southeastern United States, whereas A. pholeter is restricted to very specialized organic muck habitats and is syntopic with A. means. Here we present analyses of sequences of mitochondrial and nuclear loci from across the distribution of the three taxa to assess lineage diversity, relationships, and relative timing of divergence in amphiumid salamanders. In addition we analyze the evolution of gigantism in the clade. Our analyses indicate three lineages that have diverged since the late Miocene, that correspond to the three currently recognized species, but the two gigantic species are not each other's closest relatives. Given that the most closely related salamander families and fossil amphiumids from the Upper Cretaceous and Paleocene are relatively small, our results suggest at least two extreme changes in body size within the Amphuimidae. Gigantic body size either evolved once as the ancestral condition of modern amphiumas, with a subsequent strong size reduction in A. pholeter, or gigantism independently evolved twice in the modern species, A. means and A. tridactylum. These patterns are concordant with differences in habitat breadth and range size among lineages, and have implications for reproductive isolation and diversification of amphiumid salamanders. PMID:19461997

  5. Formación y evolución de planetas gigantes

    NASA Astrophysics Data System (ADS)

    Benvenuto, O. G.; Brunini, A.

    Presentamos el estado actual del trabajo que estamos realizando en el estudio de la formación de planetas gigantes. Detallamos los algoritmos numéricos necesarios para realizar este tipo de cálculo. Presentamos algunos resultados de la formación de objetos con masas de hasta una docena de veces la del planeta Júpiter, resaltando las principales caracteríticas. Finalmente detallamos los problemas que pensamos abordar en un futuro cercano en este tema de investigación.

  6. Fungal Cell Gigantism during Mammalian Infection

    PubMed Central

    Zaragoza, Oscar; García-Rodas, Rocío; Nosanchuk, Joshua D.; Cuenca-Estrella, Manuel; Rodríguez-Tudela, Juan Luis; Casadevall, Arturo

    2010-01-01

    The interaction between fungal pathogens with the host frequently results in morphological changes, such as hyphae formation. The encapsulated pathogenic fungus Cryptococcus neoformans is not considered a dimorphic fungus, and is predominantly found in host tissues as round yeast cells. However, there is a specific morphological change associated with cryptococcal infection that involves an increase in capsule volume. We now report another morphological change whereby gigantic cells are formed in tissue. The paper reports the phenotypic characterization of giant cells isolated from infected mice and the cellular changes associated with giant cell formation. C. neoformans infection in mice resulted in the appearance of giant cells with cell bodies up to 30 µm in diameter and capsules resistant to stripping with ?-radiation and organic solvents. The proportion of giant cells ranged from 10 to 80% of the total lung fungal burden, depending on infection time, individual mice, and correlated with the type of immune response. When placed on agar, giant cells budded to produce small daughter cells that traversed the capsule of the mother cell at the speed of 20–50 m/h. Giant cells with dimensions that approximated those in vivo were observed in vitro after prolonged culture in minimal media, and were the oldest in the culture, suggesting that giant cell formation is an aging-dependent phenomenon. Giant cells recovered from mice displayed polyploidy, suggesting a mechanism by which gigantism results from cell cycle progression without cell fission. Giant cell formation was dependent on cAMP, but not on Ras1. Real-time imaging showed that giant cells were engaged, but not engulfed by phagocytic cells. We describe a remarkable new strategy for C. neoformans to evade the immune response by enlarging cell size, and suggest that gigantism results from replication without fission, a phenomenon that may also occur with other fungal pathogens. PMID:20585557

  7. Ependimoma myxopapilar sacro gigante con osteolisis

    PubMed Central

    Ajler, Pablo; Landriel, Federico; Goldschmidt, Ezequiel; Campero, Álvaro; Yampolsky, Claudio

    2014-01-01

    Objetivo: la presentación de un caso de una paciente con un ependimoma sacro con extensa infiltración y destrucción ósea local. Descripción del caso: una mujer de 53 años acudió a la consulta por dolor lumbosacro y alteraciones sensitivas perineales y esfinterianas. La imágenes por Resonancia Magnética (IRM) y la Tomografía Axial Computada (TAC) mostraron una lesión expansiva gigante a nivel S2-S4 con extensa osteólisis e invasión de tejidos adyacentes. Se realizó una exéresis tumoral completa con mejoría del estatus funcional. La anatomía patológica informó ependimoma mixopapilar. Discusión: la extensión de la resección quirúrgica es el mejor predictor de buen pronóstico. El tratamiento radiante se reserva como opción adyuvante para las resecciones incompletas y recidiva tumoral. La quimioterapia sólo debería utilizarse en casos en que la cirugía y la radioterapia estén contraindicadas. Conclusión: Los ependimomas mixopapilares sacros con destrucción ósea y presentación intra y extradural son muy infrecuentes y deben ser tenidos en cuenta entre los diagnósticos diferenciales preoperatorios. Su resección total, siempre que sea posible, es la mejor alternativa terapéutica. PMID:25165615

  8. On the Vertical Structuring of Gigantic Jets

    NASA Astrophysics Data System (ADS)

    Da Silva, C.; Pasko, V. P.

    2013-12-01

    Gigantic Jets (GJs) are large-scale electrical discharges between the thundercloud tops and the lower ionosphere. It is estimated that an individual GJ can contribute as much as cloud-to-ground lightning in discharging a thunderstorm system, transferring hundreds of coulombs from thundercloud to the ionosphere [Cummer et al., Nat. Geosci., 2, 617-620, 2009]. GJs are initiated deep inside the thundercloud as intracloud lightning discharges. Owing to a charge imbalance, meaning the upper charge center is depleted with respect to the midlevel charge center, the upward-directed lightning leaders manage to escape through the thundercloud top to form GJs [Krehbiel et al., Nat. Geosci., 1, 233-237, 2008]. As a GJ leader crosses the stratosphere its streamer zone becomes longer and longer, due to the dynamics of streamer growth in a medium with exponentially-decreasing air density, such as in the Earth's atmosphere [Raizer et al., GRL, 33, L23801, 2006]. The speed at which a leader propagates is limited by the air heating of every newly formed leader section, rate of which is slower at upper altitudes in the Earth's atmosphere [da Silva and Pasko, GRL, 39, L13805, 2012]. Despite the expected deceleration of an upward-directed leader, GJs are observed to accelerate as they approach the ionosphere. To address this issue, we propose a simple time-dynamic model for GJ propagation that simulates the upward propagation of a leader discharge accounting for the effects of the expansion of its streamer zone. We propose that the GJ acceleration is a consequence of its vertical structuring and, therefore, can be used to trace the transition altitude between the leader and streamer zone sections of GJs [da Silva and Pasko, GRL, 40, 12, 3315-3319, 2013]. Leaders and streamers are very different electrical discharges in terms of the degree of ionization, temperature, and composition of the plasma inside their channels. A correct description of the vertical structuring of GJs is of fundamental importance for evaluation of their effects in the stratosphere and mesosphere.

  9. Assembly of the Gigantic Hemoglobin of the Earthworm Lumbricus terrestris

    E-print Network

    Riggs, Austen

    Assembly of the Gigantic Hemoglobin of the Earthworm Lumbricus terrestris ROLES OF SUBUNIT 77030 The extracellular hemoglobin of the earthworm Lum- bricus terrestris has four major kinds of O2 not only by direct quantita- tive analysis of the intact hemoglobin but also by the fact that the addition

  10. Glassy protein dynamics and gigantic solvent reorganization energy of plastocyanin

    E-print Network

    Matyushov, Dmitry

    Glassy protein dynamics and gigantic solvent reorganization energy of plastocyanin David N. Le that is small. #12;Solution Electron Transfer Protein Electron Transfer Y = X + q Proteins have glassy site: 1 copper ion, 4 ligands * 2 oxidation states: red, ox * 2 temperatures: 285K, 310K * TIP3P water

  11. Management of type 2 diabetes mellitus associated with pituitary gigantism.

    PubMed

    Ali, Omar; Banerjee, Swati; Kelly, Daniel F; Lee, Phillip D K

    2007-01-01

    Pituitary gigantism, a condition of endogenous growth hormone (GH) hypersecretion prior to epiphyseal closure, is a rare condition. In the adult condition of GH excess, acromegaly, the occurrence of type 2 diabetes mellitus (T2DM) and diabetic ketoacidosis (DKA) have been reported, with resolution following normalization of GH levels. We report the case of a 16-year-old male with pituitary gigantism due to a large invasive suprasellar adenoma who presented with T2DM and DKA. Despite surgical de-bulking, radiotherapy and medical treatment with cabergoline and pegvisomant, GH and insulin-like growth factor-I (IGF-I) levels remained elevated. However, the T2DM and recurrent DKA were successfully managed with metformin and low-dose glargine insulin, respectively. We review the pathophysiology of T2DM and DKA in growth hormone excess and available treatment options. PMID:17629784

  12. Proteus syndrome: A rare cause of gigantic limb

    PubMed Central

    Chakrabarti, Nandini; Chattopadhyay, Chandan; Bhuban, Majhi; Pal, Salil Kumar

    2014-01-01

    A congenital disorder with variable manifestations, including partial gigantism of the hands and feet with hypertrophy of soles, nevi, hemihypertrophy, gynecomastia, macrocephaly and other skull abnormalities, and abdominal lipomatosis. The cause is unknown, although a genetic origin, generally of autosomal-dominant transmission, has been conjectured. Symptoms can be treated, but there is no known cure. We present the case of a young male with grotesque overgrowth of the right lower limb, splenomegaly and multiple nevi. Angiography revealed venous malformation within the limb. The findings are in conformity to the criteria for the Proteus syndrome. PMID:24860761

  13. Proteus syndrome: A rare cause of gigantic limb.

    PubMed

    Chakrabarti, Nandini; Chattopadhyay, Chandan; Bhuban, Majhi; Pal, Salil Kumar

    2014-04-01

    A congenital disorder with variable manifestations, including partial gigantism of the hands and feet with hypertrophy of soles, nevi, hemihypertrophy, gynecomastia, macrocephaly and other skull abnormalities, and abdominal lipomatosis. The cause is unknown, although a genetic origin, generally of autosomal-dominant transmission, has been conjectured. Symptoms can be treated, but there is no known cure. We present the case of a young male with grotesque overgrowth of the right lower limb, splenomegaly and multiple nevi. Angiography revealed venous malformation within the limb. The findings are in conformity to the criteria for the Proteus syndrome. PMID:24860761

  14. Gigantic jets between a thundercloud and the ionosphere.

    PubMed

    Su, H T; Hsu, R R; Chen, A B; Wang, Y C; Hsiao, W S; Lai, W C; Lee, L C; Sato, M; Fukunishi, H

    2003-06-26

    Transient luminous events in the atmosphere, such as lighting-induced sprites and upwardly discharging blue jets, were discovered recently in the region between thunderclouds and the ionosphere. In the conventional picture, the main components of Earth's global electric circuit include thunderstorms, the conducting ionosphere, the downward fair-weather currents and the conducting Earth. Thunderstorms serve as one of the generators that drive current upward from cloud tops to the ionosphere, where the electric potential is hundreds of kilovolts higher than Earth's surface. It has not been clear, however, whether all the important components of the global circuit have even been identified. Here we report observations of five gigantic jets that establish a direct link between a thundercloud (altitude approximately 16 km) and the ionosphere at 90 km elevation. Extremely-low-frequency radio waves in four events were detected, while no cloud-to-ground lightning was observed to trigger these events. Our result indicates that the extremely-low-frequency waves were generated by negative cloud-to-ionosphere discharges, which would reduce the electrical potential between ionosphere and ground. Therefore, the conventional picture of the global electric circuit needs to be modified to include the contributions of gigantic jets and possibly sprites. PMID:12827198

  15. Gigantic Surface Lifetime of an Intrinsic Topological Insulator

    NASA Astrophysics Data System (ADS)

    Neupane, Madhab; Xu, Su-Yang; Ishida, Yukiaki; Jia, Shuang; Fregoso, Benjamin M.; Liu, Chang; Belopolski, Ilya; Bian, Guang; Alidoust, Nasser; Durakiewicz, Tomasz; Galitski, Victor; Shin, Shik; Cava, Robert J.; Hasan, M. Zahid

    2015-09-01

    The interaction between light and novel two-dimensional electronic states holds promise to realize new fundamental physics and optical devices. Here, we use pump-probe photoemission spectroscopy to study the optically excited Dirac surface states in the bulk-insulating topological insulator Bi2Te2Se and reveal optical properties that are in sharp contrast to those of bulk-metallic topological insulators. We observe a gigantic optical lifetime exceeding 4 ? s (1 ? s =10-6 s ) for the surface states in Bi2Te2Se , whereas the lifetime in most topological insulators, such as Bi2Se3 , has been limited to a few picoseconds (1 ps =10-12 s ). Moreover, we discover a surface photovoltage, a shift of the chemical potential of the Dirac surface states, as large as 100 mV. Our results demonstrate a rare platform to study charge excitation and relaxation in energy and momentum space in a two-dimensional system.

  16. Gigantism and comparative life-history parameters of tyrannosaurid dinosaurs.

    PubMed

    Erickson, Gregory M; Makovicky, Peter J; Currie, Philip J; Norell, Mark A; Yerby, Scott A; Brochu, Christopher A

    2004-08-12

    How evolutionary changes in body size are brought about by variance in developmental timing and/or growth rates (also known as heterochrony) is a topic of considerable interest in evolutionary biology. In particular, extreme size change leading to gigantism occurred within the dinosaurs on multiple occasions. Whether this change was brought about by accelerated growth, delayed maturity or a combination of both processes is unknown. A better understanding of relationships between non-avian dinosaur groups and the newfound capacity to reconstruct their growth curves make it possible to address these questions quantitatively. Here we study growth patterns within the Tyrannosauridae, the best known group of large carnivorous dinosaurs, and determine the developmental means by which Tyrannosaurus rex, weighing 5,000 kg and more, grew to be one of the most enormous terrestrial carnivorous animals ever. T. rex had a maximal growth rate of 2.1 kg d(-1), reached skeletal maturity in two decades and lived for up to 28 years. T. rex's great stature was primarily attained by accelerating growth rates beyond that of its closest relatives. PMID:15306807

  17. Gigantic surface lifetime of an intrinsic topological insulator.

    PubMed

    Neupane, Madhab; Xu, Su-Yang; Ishida, Yukiaki; Jia, Shuang; Fregoso, Benjamin M; Liu, Chang; Belopolski, Ilya; Bian, Guang; Alidoust, Nasser; Durakiewicz, Tomasz; Galitski, Victor; Shin, Shik; Cava, Robert J; Hasan, M Zahid

    2015-09-11

    The interaction between light and novel two-dimensional electronic states holds promise to realize new fundamental physics and optical devices. Here, we use pump-probe photoemission spectroscopy to study the optically excited Dirac surface states in the bulk-insulating topological insulator Bi_{2}Te_{2}Se and reveal optical properties that are in sharp contrast to those of bulk-metallic topological insulators. We observe a gigantic optical lifetime exceeding 4???s (1???s=10^{-6}??s) for the surface states in Bi_{2}Te_{2}Se, whereas the lifetime in most topological insulators, such as Bi_{2}Se_{3}, has been limited to a few picoseconds (1??ps=10^{-12}??s). Moreover, we discover a surface photovoltage, a shift of the chemical potential of the Dirac surface states, as large as 100 mV. Our results demonstrate a rare platform to study charge excitation and relaxation in energy and momentum space in a two-dimensional system. PMID:26406846

  18. Why might they be giants? Towards an understanding of polar gigantism.

    PubMed

    Moran, Amy L; Woods, H Arthur

    2012-06-15

    Beginning with the earliest expeditions to the poles, over 100 years ago, scientists have compiled an impressive list of polar taxa whose body sizes are unusually large. This phenomenon has become known as 'polar gigantism'. In the intervening years, biologists have proposed a multitude of hypotheses to explain polar gigantism. These hypotheses run the gamut from invoking release from physical and physiological constraints, to systematic changes in developmental trajectories, to community-level outcomes of broader ecological and evolutionary processes. Here we review polar gigantism and emphasize two main problems. The first is to determine the true strength and generality of this pattern: how prevalent is polar gigantism across taxonomic units? Despite many published descriptions of polar giants, we still have a poor grasp of whether these species are unusual outliers or represent more systematic shifts in distributions of body size. Indeed, current data indicate that some groups show gigantism at the poles whereas others show nanism. The second problem is to identify underlying mechanisms or processes that could drive taxa, or even just allow them, to evolve especially large body size. The contenders are diverse and no clear winner has yet emerged. Distinguishing among the contenders will require better sampling of taxa in both temperate and polar waters and sustained efforts by comparative physiologists and evolutionary ecologists in a strongly comparative framework. PMID:22623187

  19. Biology of the sauropod dinosaurs: the evolution of gigantism

    PubMed Central

    Sander, P Martin; Christian, Andreas; Clauss, Marcus; Fechner, Regina; Gee, Carole T; Griebeler, Eva-Maria; Gunga, Hanns-Christian; Hummel, Jürgen; Mallison, Heinrich; Perry, Steven F; Preuschoft, Holger; Rauhut, Oliver W M; Remes, Kristian; Tütken, Thomas; Wings, Oliver; Witzel, Ulrich

    2011-01-01

    The herbivorous sauropod dinosaurs of the Jurassic and Cretaceous periods were the largest terrestrial animals ever, surpassing the largest herbivorous mammals by an order of magnitude in body mass. Several evolutionary lineages among Sauropoda produced giants with body masses in excess of 50 metric tonnes by conservative estimates. With body mass increase driven by the selective advantages of large body size, animal lineages will increase in body size until they reach the limit determined by the interplay of bauplan, biology, and resource availability. There is no evidence, however, that resource availability and global physicochemical parameters were different enough in the Mesozoic to have led to sauropod gigantism. We review the biology of sauropod dinosaurs in detail and posit that sauropod gigantism was made possible by a specific combination of plesiomorphic characters (phylogenetic heritage) and evolutionary innovations at different levels which triggered a remarkable evolutionary cascade. Of these key innovations, the most important probably was the very long neck, the most conspicuous feature of the sauropod bauplan. Compared to other herbivores, the long neck allowed more efficient food uptake than in other large herbivores by covering a much larger feeding envelope and making food accessible that was out of the reach of other herbivores. Sauropods thus must have been able to take up more energy from their environment than other herbivores. The long neck, in turn, could only evolve because of the small head and the extensive pneumatization of the sauropod axial skeleton, lightening the neck. The small head was possible because food was ingested without mastication. Both mastication and a gastric mill would have limited food uptake rate. Scaling relationships between gastrointestinal tract size and basal metabolic rate (BMR) suggest that sauropods compensated for the lack of particle reduction with long retention times, even at high uptake rates. The extensive pneumatization of the axial skeleton resulted from the evolution of an avian-style respiratory system, presumably at the base of Saurischia. An avian-style respiratory system would also have lowered the cost of breathing, reduced specific gravity, and may have been important in removing excess body heat. Another crucial innovation inherited from basal dinosaurs was a high BMR. This is required for fueling the high growth rate necessary for a multi-tonne animal to survive to reproductive maturity. The retention of the plesiomorphic oviparous mode of reproduction appears to have been critical as well, allowing much faster population recovery than in megaherbivore mammals. Sauropods produced numerous but small offspring each season while land mammals show a negative correlation of reproductive output to body size. This permitted lower population densities in sauropods than in megaherbivore mammals but larger individuals. Our work on sauropod dinosaurs thus informs us about evolutionary limits to body size in other groups of herbivorous terrestrial tetrapods. Ectothermic reptiles are strongly limited by their low BMR, remaining small. Mammals are limited by their extensive mastication and their vivipary, while ornithsichian dinosaurs were only limited by their extensive mastication, having greater average body sizes than mammals. PMID:21251189

  20. An Evolutionary Cascade Model for Sauropod Dinosaur Gigantism - Overview, Update and Tests

    PubMed Central

    Sander, P. Martin

    2013-01-01

    Sauropod dinosaurs are a group of herbivorous dinosaurs which exceeded all other terrestrial vertebrates in mean and maximal body size. Sauropod dinosaurs were also the most successful and long-lived herbivorous tetrapod clade, but no abiological factors such as global environmental parameters conducive to their gigantism can be identified. These facts justify major efforts by evolutionary biologists and paleontologists to understand sauropods as living animals and to explain their evolutionary success and uniquely gigantic body size. Contributions to this research program have come from many fields and can be synthesized into a biological evolutionary cascade model of sauropod dinosaur gigantism (sauropod gigantism ECM). This review focuses on the sauropod gigantism ECM, providing an updated version based on the contributions to the PLoS ONE sauropod gigantism collection and on other very recent published evidence. The model consist of five separate evolutionary cascades (“Reproduction”, “Feeding”, “Head and neck”, “Avian-style lung”, and “Metabolism”). Each cascade starts with observed or inferred basal traits that either may be plesiomorphic or derived at the level of Sauropoda. Each trait confers hypothetical selective advantages which permit the evolution of the next trait. Feedback loops in the ECM consist of selective advantages originating from traits higher in the cascades but affecting lower traits. All cascades end in the trait “Very high body mass”. Each cascade is linked to at least one other cascade. Important plesiomorphic traits of sauropod dinosaurs that entered the model were ovipary as well as no mastication of food. Important evolutionary innovations (derived traits) were an avian-style respiratory system and an elevated basal metabolic rate. Comparison with other tetrapod lineages identifies factors limiting body size. PMID:24205267

  1. Oxygen hypothesis of polar gigantism not supported by performance of Antarctic

    E-print Network

    in hypoxia H. Arthur Woods1,*, Amy L. Moran2 , Claudia P. Arango3 , Lindy Mullen1 and Chris Shields2 1 conditions (K1.8­08C) for several million years and contain spectacular examples of gigantism. Pycnogonids, which have been evolving in very cold conditions (K1.8­08C) for several million years (Peck et al. 2006

  2. Lightning development associated with two negative gigantic jets Gaopeng Lu,1

    E-print Network

    Cummer, Steven A.

    Lightning development associated with two negative gigantic jets Gaopeng Lu,1 Steven A. Cummer,1 very highfrequency (VHF) lightning mapping networks that the associated lightning character- istics intracloud lightning with upper level channels attempting to exit the cloud, and then produced the upward

  3. Radar and lightning analyses of gigantic jet-producing storms Tiffany C. Meyer,1,2

    E-print Network

    Collett Jr., Jeffrey L.

    Radar and lightning analyses of gigantic jet-producing storms Tiffany C. Meyer,1,2 Timothy J. Lang range of very high frequency lightning mapping networks. All six were within range of operational radars and two-dimensional lightning network coverage: five within the National Lightning Detection Network

  4. Radar and lightning analyses of gigantic jet-producing storms Tiffany C. Meyer,1,2

    E-print Network

    Cummer, Steven A.

    Radar and lightning analyses of gigantic jet-producing storms Tiffany C. Meyer,1,2 Timothy J. Lang high frequency lightning mapping networks. All six were within range of operational radars and two-dimensional lightning network coverage: five within the National Lightning Detection Network and one within the Global

  5. Discovery of the Largest Orbweaving Spider Species: The Evolution of Gigantism in Nephila

    E-print Network

    Miller, Scott

    Discovery of the Largest Orbweaving Spider Species: The Evolution of Gigantism in Nephila Matjaz than 41,000 spider species are known with about 400­500 added each year, but for some well-known groups are renowned for being the largest web-spinning spiders, making the largest orb webs, and are model organisms

  6. Multiinstrumental observations of a positive gigantic jet produced by a winter thunderstorm in Europe

    E-print Network

    Cummer, Steven A.

    Multiinstrumental observations of a positive gigantic jet produced by a winter thunderstorm was short at 120­160 ms. This is the first documented GJ which emerged from a maritime winter thunderstorm and winter thunderstorms in the Mediterranean. During the trailing jet phase of the GJ, a sprite with halo

  7. Gigantic clavicle osteochondroma with carotid compression as a rare cause of stroke.

    PubMed

    Gouicem, Djelloul; Palcau, Laura; Hello, Claire Le; Coffin, Olivier; Maiza, Dominique; Berger, Ludovic

    2013-03-01

    We report the case of a 26-year-old woman who presented with embolic stroke from left common carotid artery compression by a gigantic clavicular osteochondroma. To our knowledge, this is the only such case described in the literature. The other particularity of this case is the delayed appearance of this childhood tumor. Surgery was successful, with a satisfying outcome. PMID:23446126

  8. Respiratory Evolution Facilitated the Origin of Pterosaur Flight and Aerial Gigantism

    E-print Network

    Claessens, Leon

    Respiratory Evolution Facilitated the Origin of Pterosaur Flight and Aerial Gigantism Leon P. A. M of the pulmonary system that powered flight in pterosaurs. We investigated the structure and function of the pterosaurian breathing apparatus through a broad scale comparative study of respiratory structure and function

  9. Analysis of the first gigantic jet recorded over continental North America

    NASA Astrophysics Data System (ADS)

    van der Velde, Oscar A.; Lyons, Walter A.; Nelson, Thomas E.; Cummer, Steven A.; Li, Jingbo; Bunnell, James

    2007-10-01

    Two low-light cameras near Marfa, Texas, recorded a gigantic jet over northern Mexico on 13 May 2005 at approximately 0423:50 UTC. Assuming that the farthest of two candidate storm systems was its source, the bright lower channel ended in a fork at around 50-59 km height with the very dim upper branches extended to 69-80 km altitude. During the time window containing the jet, extremely low frequency magnetic field recordings show that there was no fast charge moment change larger than 50 coulomb times kilometers (C km) but there was a larger and slower charge moment change of 520 C km over 70 ms. The likely parent thunderstorm was a high-precipitation supercell cluster containing a persistent mesocyclone, with radar echo tops of at least 17 km. However, photogrammetric analysis suggests that the gigantic jet occurred over the forward flank downdraft region with echo tops of 14 km. This part of the supercell may have had an inverted-polarity charge configuration as evidenced by positive cloud-to-ground lightning flashes (+CG) dominating over negative flashes (-CG), while -CGs occurred under the downwind anvil. Four minutes before the gigantic jet, -CG activity practically ceased in this area, while +CG rates increased, culminating during the 20 s leading up to the gigantic jet with four National Lightning Detection Network-detected +CGs. A relative lull in lightning activity of both polarities was observed for up to 1.5 min after the gigantic jet. The maturing storm subsequently produced 30 sprites between 0454 and 0820 UTC, some associated with extremely large impulse charge moment change values.

  10. Gigantic self-confined pahoehoe inflated lava flows in Argentina

    NASA Astrophysics Data System (ADS)

    Pasquare', G.; Bistacchi, A.

    2007-05-01

    The largest lava flows on Earth are pahoehoe basalts emplaced by inflation, a process which can change lava lobes initially a few decimetres thick into large lava sheets several metres thick. Inflation involves the initial formation of a thin, solidified, viscoelastic crust, under which liquid lava is continually added. This thermally efficient endogenous growth process explains the spread of huge volumes of lava over large, almost flat areas, as in the sheet flows which characterise the distal portions of Hawaiian volcanoes or some continental flood basalt provinces. Long, narrow, inflated pahoehoe flows have occasionally been described, either emplaced along pre-existing river channels or confined within topographic barriers. In this contribution we present previously unknown inflated pahoehoe lava flows following very long, narrow pathways over an almost flat surface, with no topographic confinement. Lava, which erupted in Late Quaternary times from the eastern tip of a 60 km long volcanic fissure in Argentina, formed several discrete flows extending as far as 180 km from the source. This fissure was characterized by a long-lasting and complex activity. Alkali-basaltic lava flows were emitted at the two extremities of the fissure system. In the intermediate section of the fissure, the Payun Matru, a great trachitic composite volcano, developed, giving rise to a large caldera which produced large pyroclastic flows. Alkali-basalts predate and postdate the trachitic activity, in fact at the end of the trachitic activity, new basaltic lava flows (mainly aa) were emitted from both ends of the fissure. We studied in details the youngest of the gigantic flows (Pampas Onduladas lava flow), which progressively develops through differing thermally-efficient flow mechanisms. The flow created a large shield volcanic structure at the eastern tip of the E-W fissure and spread to the E forming a very large and thick inflated pahoehoe sheet flow. Leaving the flanks of the volcano, the flow spreads all over a large tectonic depression, forming a large inflated pahoehoe sheet flow. The flow continues downstream, always showing typical inflation features, forming a very long and narrow tongue, developed over the nearly flat Pampa plain (gradient 0.5%) with an average width of 3 km and a length of 120 km. A peculiar feature of this portion of the flow, apart from its exceptional length, is the very low width-to-length ratio. This is even more surprising if we consider that no pre-existing topographic feature (e.g. river channel, etc.) is responsible for this behaviour, which appears to be only the result of some kind of self-confinement mechanism. The structural, morphological and eruptive complexities of this volcanic structure are exceptional by themselves since there are no similar features both in the Andes calcalkaline volcanism or in the Patagonian basaltic plateaus and they pose problems even in the nomenclatural definition of the Payun Matru as an individual volcanic construct. Moreover, understanding the mechanisms responsible for the exceptional behaviour of this lava flow may provide new constraints on the physics of inflated pahoehoe flow emplacement. Results in this direction may also offer useful proxies for interpreting volcanic processes on terrestrial planets such as Mars and Venus, on which individual lava flows of similar shape and dimensions have been observed.

  11. A gigantic nothosaur (Reptilia: Sauropterygia) from the Middle Triassic of SW China and its implication for the Triassic biotic recovery

    NASA Astrophysics Data System (ADS)

    Liu, Jun; Hu, Shi-Xue; Rieppel, Olivier; Jiang, Da-Yong; Benton, Michael J.; Kelley, Neil P.; Aitchison, Jonathan C.; Zhou, Chang-Yong; Wen, Wen; Huang, Jin-Yuan; Xie, Tao; Lv, Tao

    2014-11-01

    The presence of gigantic apex predators in the eastern Panthalassic and western Tethyan oceans suggests that complex ecosystems in the sea had become re-established in these regions at least by the early Middle Triassic, after the Permian-Triassic mass extinction (PTME). However, it is not clear whether oceanic ecosystem recovery from the PTME was globally synchronous because of the apparent lack of such predators in the eastern Tethyan/western Panthalassic region prior to the Late Triassic. Here we report a gigantic nothosaur from the lower Middle Triassic of Luoping in southwest China (eastern Tethyan ocean), which possesses the largest known lower jaw among Triassic sauropterygians. Phylogenetic analysis suggests parallel evolution of gigantism in Triassic sauropterygians. Discovery of this gigantic apex predator, together with associated diverse marine reptiles and the complex food web, indicates global recovery of shallow marine ecosystems from PTME by the early Middle Triassic.

  12. A gigantic nothosaur (Reptilia: Sauropterygia) from the Middle Triassic of SW China and its implication for the Triassic biotic recovery

    PubMed Central

    Liu, Jun; Hu, Shi-xue; Rieppel, Olivier; Jiang, Da-yong; Benton, Michael J.; Kelley, Neil P.; Aitchison, Jonathan C.; Zhou, Chang-yong; Wen, Wen; Huang, Jin-yuan; Xie, Tao; Lv, Tao

    2014-01-01

    The presence of gigantic apex predators in the eastern Panthalassic and western Tethyan oceans suggests that complex ecosystems in the sea had become re-established in these regions at least by the early Middle Triassic, after the Permian-Triassic mass extinction (PTME). However, it is not clear whether oceanic ecosystem recovery from the PTME was globally synchronous because of the apparent lack of such predators in the eastern Tethyan/western Panthalassic region prior to the Late Triassic. Here we report a gigantic nothosaur from the lower Middle Triassic of Luoping in southwest China (eastern Tethyan ocean), which possesses the largest known lower jaw among Triassic sauropterygians. Phylogenetic analysis suggests parallel evolution of gigantism in Triassic sauropterygians. Discovery of this gigantic apex predator, together with associated diverse marine reptiles and the complex food web, indicates global recovery of shallow marine ecosystems from PTME by the early Middle Triassic. PMID:25429609

  13. Gigantic Cosmic Corkscrew Reveals New Details About Mysterious Microquasar

    NASA Astrophysics Data System (ADS)

    2004-10-01

    Making an extra effort to image a faint, gigantic corkscrew traced by fast protons and electrons shot out from a mysterious microquasar paid off for a pair of astrophysicists who gained new insights into the beast's inner workings and also resolved a longstanding dispute over the object's distance. Microquasar SS 433 VLA Image of Microquasar SS 433 CREDIT: Blundell & Bowler, NRAO/AUI/NSF (Click on Image for Larger Version) The astrophysicists used the National Science Foundation's Very Large Array (VLA) radio telescope to capture the faintest details yet seen in the plasma jets emerging from the microquasar SS 433, an object once dubbed the "enigma of the century." As a result, they have changed scientists' understanding of the jets and settled the controversy over its distance "beyond all reasonable doubt," they said. SS 433 is a neutron star or black hole orbited by a "normal" companion star. The powerful gravity of the neutron star or black hole draws material from the stellar wind of its companion into an accretion disk of material tightly circling the dense central object prior to being pulled onto it. This disk propels jets of fast protons and electrons outward from its poles at about a quarter of the speed of light. The disk in SS 433 wobbles like a child's top, causing its jets to trace a corkscrew in the sky every 162 days. The new VLA study indicates that the speed of the ejected particles varies over time, contrary to the traditional model for SS 433. "We found that the actual speed varies between 24 percent to 28 percent of light speed, as opposed to staying constant," said Katherine Blundell, of the University of Oxford in the United Kingdom. "Amazingly, the jets going in both directions change their speeds simultaneously, producing identical speeds in both directions at any given time," Blundell added. Blundell worked with Michael Bowler, also of Oxford. The scientists' findings have been accepted by the Astrophysical Journal Letters. SS 433 New VLA Image of SS 433: Red-and-Blue Line Shows Path of Constant-Speed Jets. Note Poor Match of Path to Image. CREDIT: Blundell & Bowler, NRAO/AUI/NSF SS 433 Same Image, With Colored Beads Representing Particle Ejections at Different Speeds. Particle Path Now Matches. CREDIT: Blundell & Bowler, NRAO/AUI/NSF Click Here for Page of Full-Sized Graphics The new VLA image shows two full turns of the jets' corkscrew on both sides of the core. Analyzing the image showed that if material came from the core at a constant speed, the jet paths would not accurately match the details of the image. "By simulating ejections at varying speeds, we were able to produce an exact match to the observed structure," Blundell explained. The scientists first did their match to one of the jets. "We then were stunned to see that the varying speeds that matched the structure of one jet also exactly reproduced the other jet's path," Blundell said. Matching the speeds in the two jets reproduced the observed structure even allowing for the fact that, because one jet is moving more nearly away from us than the other, it takes light longer to reach us from it, she added. The astrophysicists speculate that the changes in ejection speed may be caused by changes in the rate at which material is transferred from the companion star onto the accretion disk. The detailed new VLA image also allowed the astrophysicists to determine that SS 433 is nearly 18,000 light-years distant from Earth. Earlier estimates had the object, in the constellation Aquila, as near as 10,000 light-years. An accurate distance, the scientists said, now allows them to better determine the age of the shell of debris blown out by the supernova explosion that created the dense, compact object in the microquasar. Knowing the distance accurately also allows them to measure the actual brightness of the microquasar's components, and this, they said, improves their understanding of the physical processes at work in the system. The breakthrough image was made us

  14. The evolution of island gigantism and body size variation in tortoises and turtles

    PubMed Central

    Jaffe, Alexander L.; Slater, Graham J.; Alfaro, Michael E.

    2011-01-01

    Extant chelonians (turtles and tortoises) span almost four orders of magnitude of body size, including the startling examples of gigantism seen in the tortoises of the Galapagos and Seychelles islands. However, the evolutionary determinants of size diversity in chelonians are poorly understood. We present a comparative analysis of body size evolution in turtles and tortoises within a phylogenetic framework. Our results reveal a pronounced relationship between habitat and optimal body size in chelonians. We found strong evidence for separate, larger optimal body sizes for sea turtles and island tortoises, the latter showing support for the rule of island gigantism in non-mammalian amniotes. Optimal sizes for freshwater and mainland terrestrial turtles are similar and smaller, although the range of body size variation in these forms is qualitatively greater. The greater number of potential niches in freshwater and terrestrial environments may mean that body size relationships are more complicated in these habitats. PMID:21270022

  15. Cope's Rule and Romer's theory: patterns of diversity and gigantism in eurypterids and Palaeozoic vertebrates.

    PubMed

    Lamsdell, James C; Braddy, Simon J

    2010-04-23

    Gigantism is widespread among Palaeozoic arthropods, yet causal mechanisms, particularly the role of (abiotic) environmental factors versus (biotic) competition, remain unknown. The eurypterids (Arthropoda: Chelicerata) include the largest arthropods; gigantic predatory pterygotids (Eurypterina) during the Siluro-Devonian and bizarre sweep-feeding hibbertopterids (Stylonurina) from the Carboniferous to end-Permian. Analysis of family-level originations and extinctions among eurypterids and Palaeozoic vertebrates show that the diversity of Eurypterina waned during the Devonian, while the Placodermi radiated, yet Stylonurina remained relatively unaffected; adopting a sweep-feeding strategy they maintained their large body size by avoiding competition, and persisted throughout the Late Palaeozoic while the predatory nektonic Eurypterina (including the giant pterygotids) declined during the Devonian, possibly out-competed by other predators including jawed vertebrates. PMID:19828493

  16. Starvation reveals the cause of infection-induced castration and gigantism

    PubMed Central

    Cressler, Clayton E.; Nelson, William A.; Day, Troy; McCauley, Edward

    2014-01-01

    Parasites often induce life-history changes in their hosts. In many cases, these infection-induced life-history changes are driven by changes in the pattern of energy allocation and utilization within the host. Because these processes will affect both host and parasite fitness, it can be challenging to determine who benefits from them. Determining the causes and consequences of infection-induced life-history changes requires the ability to experimentally manipulate life history and a framework for connecting life history to host and parasite fitness. Here, we combine a novel starvation manipulation with energy budget models to provide new insights into castration and gigantism in the Daphnia magna–Pasteuria ramosa host–parasite system. Our results show that starvation primarily affects investment in reproduction, and increasing starvation stress reduces gigantism and parasite fitness without affecting castration. These results are consistent with an energetic structure where the parasite uses growth energy as a resource. This finding gives us new understanding of the role of castration and gigantism in this system, and how life-history variation will affect infection outcome and epidemiological dynamics. The approach of combining targeted life-history manipulations with energy budget models can be adapted to understand life-history changes in other disease systems. PMID:25143034

  17. Starvation reveals the cause of infection-induced castration and gigantism.

    PubMed

    Cressler, Clayton E; Nelson, William A; Day, Troy; McCauley, Edward

    2014-10-01

    Parasites often induce life-history changes in their hosts. In many cases, these infection-induced life-history changes are driven by changes in the pattern of energy allocation and utilization within the host. Because these processes will affect both host and parasite fitness, it can be challenging to determine who benefits from them. Determining the causes and consequences of infection-induced life-history changes requires the ability to experimentally manipulate life history and a framework for connecting life history to host and parasite fitness. Here, we combine a novel starvation manipulation with energy budget models to provide new insights into castration and gigantism in the Daphnia magna-Pasteuria ramosa host-parasite system. Our results show that starvation primarily affects investment in reproduction, and increasing starvation stress reduces gigantism and parasite fitness without affecting castration. These results are consistent with an energetic structure where the parasite uses growth energy as a resource. This finding gives us new understanding of the role of castration and gigantism in this system, and how life-history variation will affect infection outcome and epidemiological dynamics. The approach of combining targeted life-history manipulations with energy budget models can be adapted to understand life-history changes in other disease systems. PMID:25143034

  18. The triangulation of the gigantic jets observed by the optical observation network in Taiwan

    NASA Astrophysics Data System (ADS)

    Chen, Alfred B.; Huang, Chien-Fong; Peng, Kang-Ming; Su, Han-Tzong; Hsu, Rue-Ron

    2015-04-01

    The optical triangulation of sprites and elves by the multiple sites has been done in the past decades, but the similar observation on gigantic jets has never been reported yet. A ground optical observation network consisting of four stations at Kimen, Penghu, Tainan, and Taitung (from west to east) has been established in Taiwan since 2012. Each station equipped with two sets of Watec low-light sensitivity cameras, and the elevation and azimuth of the observation can be fully remote controlled to point toward the on-going convection system in the vicinity of Taiwan. In summer 2014, more than 6 gigantic jets were captured by at least two stations successfully. The triangulation and ULF sferics of these interesting events provides an excellent chance to explore the spatial and temporal evolution of the jets in different phases. In this presentation, this ground observation network will be introduced, the detail evolution of the recorded gigantic jets is presented. The preliminary result implies that the jets may not pop from the cloudtop straightforwardly, and some twists occur during the propagation of the jets. A more complicated analysis of the tomography for the advanced triangulation will be mentioned, too.

  19. Clinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients.

    PubMed

    Rostomyan, Liliya; Daly, Adrian F; Petrossians, Patrick; Nachev, Emil; Lila, Anurag R; Lecoq, Anne-Lise; Lecumberri, Beatriz; Trivellin, Giampaolo; Salvatori, Roberto; Moraitis, Andreas G; Holdaway, Ian; Kranenburg-van Klaveren, Dianne J; Chiara Zatelli, Maria; Palacios, Nuria; Nozieres, Cecile; Zacharin, Margaret; Ebeling, Tapani; Ojaniemi, Marja; Rozhinskaya, Liudmila; Verrua, Elisa; Jaffrain-Rea, Marie-Lise; Filipponi, Silvia; Gusakova, Daria; Pronin, Vyacheslav; Bertherat, Jerome; Belaya, Zhanna; Ilovayskaya, Irena; Sahnoun-Fathallah, Mona; Sievers, Caroline; Stalla, Gunter K; Castermans, Emilie; Caberg, Jean-Hubert; Sorkina, Ekaterina; Auriemma, Renata Simona; Mittal, Sachin; Kareva, Maria; Lysy, Philippe A; Emy, Philippe; De Menis, Ernesto; Choong, Catherine S; Mantovani, Giovanna; Bours, Vincent; De Herder, Wouter; Brue, Thierry; Barlier, Anne; Neggers, Sebastian J C M M; Zacharieva, Sabina; Chanson, Philippe; Shah, Nalini Samir; Stratakis, Constantine A; Naves, Luciana A; Beckers, Albert

    2015-10-01

    Despite being a classical growth disorder, pituitary gigantism has not been studied previously in a standardized way. We performed a retrospective, multicenter, international study to characterize a large series of pituitary gigantism patients. We included 208 patients (163 males; 78.4%) with growth hormone excess and a current/previous abnormal growth velocity for age or final height >2 s.d. above country normal means. The median onset of rapid growth was 13 years and occurred significantly earlier in females than in males; pituitary adenomas were diagnosed earlier in females than males (15.8 vs 21.5 years respectively). Adenomas were ?10?mm (i.e., macroadenomas) in 84%, of which extrasellar extension occurred in 77% and invasion in 54%. GH/IGF1 control was achieved in 39% during long-term follow-up. Final height was greater in younger onset patients, with larger tumors and higher GH levels. Later disease control was associated with a greater difference from mid-parental height (r=0.23, P=0.02). AIP mutations occurred in 29%; microduplication at Xq26.3 - X-linked acrogigantism (X-LAG) - occurred in two familial isolated pituitary adenoma kindreds and in ten sporadic patients. Tumor size was not different in X-LAG, AIP mutated and genetically negative patient groups. AIP-mutated and X-LAG patients were significantly younger at onset and diagnosis, but disease control was worse in genetically negative cases. Pituitary gigantism patients are characterized by male predominance and large tumors that are difficult to control. Treatment delay increases final height and symptom burden. AIP mutations and X-LAG explain many cases, but no genetic etiology is seen in >50% of cases. PMID:26187128

  20. Pituitary gigantism presenting with depressive mood disorder and diabetic ketoacidosis in an Asian adolescent.

    PubMed

    Kuo, Sheng-Fong; Chuang, Wen-Yu; Ng, Sohching; Chen, Chih-Hung; Chang, Chen-Nen; Chou, Chi-Hsiang; Weng, Wei-Chieh; Yeh, Chih-Hua; Lin, Jen-Der

    2013-01-01

    Hyperglycemia is seldom described in young patients with pituitary gigantism. Here, we describe the case of a 17-year-old Taiwanese boy who developed depressive mood disorder and diabetic ketoacidosis (DKA) at the presentation of pituitary gigantism. The boy complained of lethargy and dysphoric mood in June 2008. He presented at the emergency department with epigastralgia and dyspnea in January 2009. Results of laboratory tests suggested type 1 diabetes mellitus with DKA. However, serum C-peptide level was normal on follow-up. Although he had no obvious features of acral enlargement, a high level of insulin-like growth factor 1 was detected, and a 75 g oral glucose suppression test showed no suppression of serum growth hormone levels. A pituitary macroadenoma was found on subsequent magnetic resonance imaging. The pituitary adenoma was surgically removed, followed by gamma-knife radiosurgery, and Sandostatin long-acting release treatment. He was then administered metformin, 500 mg twice daily, and to date, his serum glycohemoglobin has been <7%. PMID:23729615

  1. Are Sick Individuals Weak Competitors? Competitive Ability of Snails Parasitized by a Gigantism-Inducing Trematode

    PubMed Central

    Seppälä, Otto; Karvonen, Anssi; Kuosa, Marja; Haataja, Maarit; Jokela, Jukka

    2013-01-01

    Parasitized individuals are often expected to be poor competitors because they are weakened by infections. Many trematode species, however, although extensively exploiting their mollusc hosts, also induce gigantism (increased host size) by diverting host resources towards growth instead of reproduction. In such systems, alternatively to reduced competitive ability due to negative effects of parasitism on host performance, larger size could allow more efficient resource acquisition and thus increase the relative competitive ability of host individuals. We addressed this hypothesis by testing the effect of a trematode parasite Diplostomum pseudospathaceum on the competitive ability of its snail host Lymnaea stagnalis. We experimentally examined the growth of snails kept in pairs in relation to their infection status and intensity of resource competition (i.e. food availability). We found that parasitized snails grew faster and their reproduction was reduced compared to unparasitized individuals indicating parasite-induced gigantism. However, growth of the snails was faster when competing with parasitized individuals compared to unparasitized snails indicating reduced competitive ability due to parasitism. The latter effect, however, was relatively weak suggesting that the effects of the parasite on snail physiology may partly override each other in determining competitive ability. PMID:24205383

  2. GaAs-oxide interface states - Gigantic photoionization via Auger-like process

    NASA Technical Reports Server (NTRS)

    Lagowski, J.; Kazior, T. E.; Gatos, H. C.; Walukiewicz, W.; Siejka, J.

    1981-01-01

    Spectral and transient responses of photostimulated current in MOS structures were employed for the study of GaAs-anodic oxide interface states. Discrete deep traps at 0.7 and 0.85 eV below the conduction band were found with concentrations of 5 x 10 to the 12th/sq cm and 7 x 10 to the 11th/sq cm, respectively. These traps coincide with interface states induced on clean GaAs surfaces by oxygen and/or metal adatoms (submonolayer coverage). In contrast to surfaces with low oxygen coverage, the GaAs-thick oxide interfaces exhibited a high density (about 10 to the 14th/sq cm) of shallow donors and acceptors. Photoexcitation of these donor-acceptor pairs led to a gigantic photoionization of deep interface states with rates 1000 times greater than direct transitions into the conduction band. The gigantic photoionization is explained on the basis of energy transfer from excited donor-acceptor pairs to deep states.

  3. Facile Synthesis of Monodisperse Microspheres and Gigantic Hollow Shells of Mesoporous Silica in Mixed Water-Ethanol Solvents

    E-print Network

    Qi, Limin

    , a variety of spherical templates, such as polymer latex particles,17 emulsions,18-25 vesicles,26 process of gigantic hollow shells of mesoporous silica through templating emulsion droplets of TEOS-28 and polymer aggregates,29 have been employed in combination with surfactant templates for the dual

  4. Web gigantism in Darwin's bark spider, a new species from Madagascar (Araneidae: Caerostris) Matjaz Kuntner1,2

    E-print Network

    Agnarsson, Ingi

    Web gigantism in Darwin's bark spider, a new species from Madagascar (Araneidae: Caerostris) Matjaz, is grossly underestimated. Most species build large webs at forest edges, clearings, and gardens niche: casting its web across streams, rivers and lakes, so that the orb is suspended above water

  5. Familial gigantism.

    PubMed

    Herder, Wouter W de

    2012-01-01

    Familial GH-secreting tumors are seen in association with three separate hereditary clinical syndromes: multiple endocrine neoplasia type 1, Carney complex, and familial isolated pituitary adenomas. PMID:22584702

  6. A gigantic, exceptionally complete titanosaurian sauropod dinosaur from southern Patagonia, Argentina.

    PubMed

    Lacovara, Kenneth J; Lamanna, Matthew C; Ibiricu, Lucio M; Poole, Jason C; Schroeter, Elena R; Ullmann, Paul V; Voegele, Kristyn K; Boles, Zachary M; Carter, Aja M; Fowler, Emma K; Egerton, Victoria M; Moyer, Alison E; Coughenour, Christopher L; Schein, Jason P; Harris, Jerald D; Martínez, Rubén D; Novas, Fernando E

    2014-01-01

    Titanosaurian sauropod dinosaurs were the most diverse and abundant large-bodied herbivores in the southern continents during the final 30 million years of the Mesozoic Era. Several titanosaur species are regarded as the most massive land-living animals yet discovered; nevertheless, nearly all of these giant titanosaurs are known only from very incomplete fossils, hindering a detailed understanding of their anatomy. Here we describe a new and gigantic titanosaur, Dreadnoughtus schrani, from Upper Cretaceous sediments in southern Patagonia, Argentina. Represented by approximately 70% of the postcranial skeleton, plus craniodental remains, Dreadnoughtus is the most complete giant titanosaur yet discovered, and provides new insight into the morphology and evolutionary history of these colossal animals. Furthermore, despite its estimated mass of about 59.3 metric tons, the bone histology of the Dreadnoughtus type specimen reveals that this individual was still growing at the time of death. PMID:25186586

  7. Pituitary tumor with gigantism, acromegaly and preclinical Cushing's disease diagnosed from the 10th row.

    PubMed

    Tourtelot, John B; Vesely, David L

    2013-08-01

    A 7'3" basketball player was noted to have 2 to 3 times thicker tissue in his hands than 6'10" players by an endocrinologist sitting 10 rows above the player in a basketball arena. This led to the diagnosis of pituitary gigantism where the history revealed that he was 7'3" at 15 years of age. At age 19 when the acryl enlargement was noted, a diagnostic workup revealed elevated growth hormones and insulin-like growth factor 1 (IGF-1) with a 2 × 1.3 cm pituitary tumor. His history suggested that his epiphyseal plates had closed at age 15, and because he continued to produce IGF-1, he now has acromegaly. His elevated adrenocorticotropic hormone (ACTH) before surgery suggests that he also had preclinical Cushing's disease. After pituitary transsphenoidal surgery, all acryl enlargement in hands and ligaments disappeared. His growth hormone, IGF-1 and ACTH returned to normal 2 weeks after surgery. PMID:23462247

  8. Early descriptions of acromegaly and gigantism and their historical evolution as clinical entities.

    PubMed

    Mammis, Antonios; Eloy, Jean Anderson; Liu, James K

    2010-10-01

    Giants have been a subject of fascination throughout history. Whereas descriptions of giants have existed in the lay literature for millennia, the first attempt at a medical description was published by Johannes Wier in 1567. However, it was Pierre Marie, in 1886, who established the term "acromegaly" for the first time and established a distinct clinical diagnosis with clear clinical descriptions in 2 patients with the characteristic presentation. Multiple autopsy findings revealed a consistent correlation between acromegaly and pituitary enlargement. In 1909, Harvey Cushing postulated a “hormone of growth" as the underlying pathophysiological trigger involved in pituitary hypersecretion in patients with acromegaly. This theory was supported by his observations of clinical remission in patients with acromegaly in whom he had performed hypophysectomy. In this paper, the authors present some of the early accounts of acromegaly and gigantism, and describe its historical evolution as a medical and surgical entity. PMID:20887119

  9. Intraspecific competition and high food availability are associated with insular gigantism in a lizard

    NASA Astrophysics Data System (ADS)

    Pafilis, Panayiotis; Meiri, Shai; Foufopoulos, Johannes; Valakos, Efstratios

    2009-09-01

    Resource availability, competition, and predation commonly drive body size evolution. We assess the impact of high food availability and the consequent increased intraspecific competition, as expressed by tail injuries and cannibalism, on body size in Skyros wall lizards ( Podarcis gaigeae). Lizard populations on islets surrounding Skyros (Aegean Sea) all have fewer predators and competitors than on Skyros but differ in the numbers of nesting seabirds. We predicted the following: (1) the presence of breeding seabirds (providing nutrients) will increase lizard population densities; (2) dense lizard populations will experience stronger intraspecific competition; and (3) such aggression, will be associated with larger average body size. We found a positive correlation between seabird and lizard densities. Cannibalism and tail injuries were considerably higher in dense populations. Increases in cannibalism and tail loss were associated with large body sizes. Adult cannibalism on juveniles may select for rapid growth, fuelled by high food abundance, setting thus the stage for the evolution of gigantism.

  10. Gate-tunable gigantic lattice deformation in VO{sub 2}

    SciTech Connect

    Okuyama, D. E-mail: nakano@imr.tohoku.ac.jp Hatano, T.; Nakano, M. E-mail: nakano@imr.tohoku.ac.jp; Takeshita, S.; Ohsumi, H.; Tardif, S.; Shibuya, K.; Yumoto, H.; Koyama, T.; Ohashi, H.; Takata, M.; Kawasaki, M.; Tokura, Y.; Iwasa, Y. E-mail: nakano@imr.tohoku.ac.jp; Arima, T.

    2014-01-13

    We examined the impact of electric field on crystal lattice of vanadium dioxide (VO{sub 2}) in a field-effect transistor geometry by in-situ synchrotron x-ray diffraction measurements. Whereas the c-axis lattice parameter of VO{sub 2} decreases through the thermally induced insulator-to-metal phase transition, the gate-induced metallization was found to result in a significant increase of the c-axis length by almost 1% from that of the thermally stabilized insulating state. We also found that this gate-induced gigantic lattice deformation occurs even at the thermally stabilized metallic state, enabling dynamic control of c-axis lattice parameter by more than 1% at room temperature.

  11. The Early ULF Signal of the Gigantic Jets Revealed By Hilbert-Huang Transform

    NASA Astrophysics Data System (ADS)

    Huang, Po-Hsun; Bing-Chih Chen, Alfred

    2015-04-01

    The conventional Fourier analysis on the sferics in ULF and VLF bandpasses has been done for years. Several phenomena e.g. whistler and Schumann resonance have been well studied by the Fourier spectrum comprehensively. But the Fourier analysis is computed by an integration over time, therefore, the temporal resolution is smoothed, and limited not only by the sampling rate but also the size of the integration window. The instantaneous frequency can't be obtained through this conventional approach. We introduce the Hilbert-Huang transform (HHT) instead of Fourier transform to analyze the sferics of TLEs recorded at Lulin observatory. The Hilbert-Huang transform decomposes a signal into so-called intrinsic mode functions (IMF), and derive instantaneous frequency data by differentiating the phase angle yielded by Hilbert transform. Our analysis of HHT on several gigantic jets recorded by ground observation surprisingly revealed an early signal of frequency-change during the phase of the leading jet, and this early signal can not be identified by Fourier analysis. In the phase of leading jet, the amplitude of the sferics remains a constant and no significant features are recognized in the recorded waveform, but an obvious frequency change about 100-200 millisecond prior to the main discharge of the full development jets (FDJs), which can be clearly recognized in the HHT spectra of all observed gigantic jets. From a further simulation, this frequency change is confirmed to come from the nature of the discharge, not an alias or a false signal generated by the analysis method. This early signal may implies an in-cloud discharge process which is suggested by Krehbiel et al. [2008

  12. A Gray-purple Mass on the Floor of the Mouth: Gigantic Mucogingival Pyogenic Granuloma in a Teenage Patient

    PubMed Central

    Brunet-LLobet, Lluís; Miranda-Rius, Jaume; Lahor-Soler, Eduard; Mrina, Ombeni; Nadal, Alfons

    2014-01-01

    Pyogenic granuloma is defined as a benign neoplasm of vascular phenotype. This case describes the clinical and histopathological features of a gigantic mucogingival pyogenic granuloma, in a 14-year-old healthy black boy. This exophytic gray-purple mass, related to a toothpick injury, had more than twelve-month evolution on the anterior mandible involving lingual area besides to the floor of the mouth pressing the right salivary duct. Conservative excision was performed, followed by uncomplicated healing with no recurrence in two years. The histopathological examination reported a pyogenic granuloma (lobular capillary haemangioma). The authors provide a discussion of the presurgical differential diagnosis of the lesion. This case report presents an extremely uncommon location of a gigantic pyogenic granuloma, involving mucogingival complex and affecting the salivary outflow. This clinical manuscript may shed light on the controversies about possible mechanisms inducing oral pyogenic granuloma. PMID:24987485

  13. GaAs-oxide interface states - A gigantic photoionization effect and its implications to the origin of these states

    NASA Technical Reports Server (NTRS)

    Lagowski, J.; Walukiewicz, W.; Kazior, T. E.; Gatos, H. C.; Siejka, J.

    1981-01-01

    Gigantic photoionization was discovered on GaAs-oxide interfaces leading to the discharge of deep surface states with rates exceeding 1000 times those of photoionization transitions to the conduction band. It exhibits a peak similar to acceptor-donor transitions and is explained as due to energy transfer from photo-excited donor-acceptor pairs to deep surface states. This new process indicates the presence of significant concentrations of shallow donor and acceptor levels not recognized in previous interface models.

  14. Peculiarities of the geologic structure of gigantic gas fields of the western Siberian oil and gas province

    SciTech Connect

    Belyi, N.

    1991-03-01

    The Western Siberian Oil and Gas Province is a unique one regarding the concentration of natural gas resources in Mesozoic terrigenous formations. Discovery of gigantic natural gas fields makes it possible to provide high level of gas production for future prospects. The USSR has enormous potential possibilities for discoveries of new natural gas fields onshore, as well as offshore. At present, three gigantic gas fields have been developed, namely Medvezhie, Urongoi, and Yamburg. The first one has been in operation for 18 years. In the Mesozoic section, three productive complexes can be noticed: Upper Cretaceous, Lower Cretaceous, and Jurassic. The Upper Cretaceous production complex is mostly explored, with unique gas resources containing mainly methane having been discovered. The Lower Cretaceous production complex is characterized by considerable lithofaceous uniformity of reservoirs. Gas pools of this complex contain considerable quantities of condensate quite often having oil rims. The Jurassic production complex, which is characterized by its complicated structure and considerable changeability of the filtration properties, is less studied. Study of the geological structural peculiarities of the gigantic gas fields of Western Siberia gives us the possibility to find new approval for the development and exploration of gas fields.

  15. Respiratory evolution facilitated the origin of pterosaur flight and aerial gigantism.

    PubMed

    Claessens, Leon P A M; O'Connor, Patrick M; Unwin, David M

    2009-01-01

    Pterosaurs, enigmatic extinct Mesozoic reptiles, were the first vertebrates to achieve true flapping flight. Various lines of evidence provide strong support for highly efficient wing design, control, and flight capabilities. However, little is known of the pulmonary system that powered flight in pterosaurs. We investigated the structure and function of the pterosaurian breathing apparatus through a broad scale comparative study of respiratory structure and function in living and extinct archosaurs, using computer-assisted tomographic (CT) scanning of pterosaur and bird skeletal remains, cineradiographic (X-ray film) studies of the skeletal breathing pump in extant birds and alligators, and study of skeletal structure in historic fossil specimens. In this report we present various lines of skeletal evidence that indicate that pterosaurs had a highly effective flow-through respiratory system, capable of sustaining powered flight, predating the appearance of an analogous breathing system in birds by approximately seventy million years. Convergent evolution of gigantism in several Cretaceous pterosaur lineages was made possible through body density reduction by expansion of the pulmonary air sac system throughout the trunk and the distal limb girdle skeleton, highlighting the importance of respiratory adaptations in pterosaur evolution, and the dramatic effect of the release of physical constraints on morphological diversification and evolutionary radiation. PMID:19223979

  16. A Thermodynamic, kinematic and microphysical analysis of a jet and gigantic jet-producing Florida thunderstorm

    NASA Astrophysics Data System (ADS)

    Lazarus, S. M.; Splitt, M. E.; Brownlee, James; Spiva, Nicholas; Liu, Ningyu

    2015-08-01

    This paper presents a meteorological analysis of a storm that produced two jets, four gigantic jets (GJ), and a starter, which were observed by two radars as well as the Kennedy Space Center 4-Dimensional Lightning Surveillance System on 3 August 2013 in Central Florida. The work is the first application of dual polarization data to a jet-producing storm and is the fifth case related to a tropical disturbance. The storm environment is consistent with the moist tropical paradigm that characterizes about three quarters of the surface and aircraft observed jet and GJ events. The most unstable (MU) convective available potential energy is not unusual for Florida summer convection and is below the climatological mean for these events. An unusual speed shear layer is located near the storm equilibrium level (EL) and the storm exhibits a tilted structure with CGs displaced upshear. The turbulence, as measured by the eddy dissipation rate, is extreme near the storm top during the event window, consistent with the GJ mixing hypothesis. The individual events are collocated with, and track along, the center axis of the divergent outflow at the EL and occur within the region of the coldest GOES IR temperatures—placing the events within the overshoot. The dual polarization data indicate a deep graupel column, extending above the mixed phase layer, to a 13 km altitude.

  17. Lower limb gigantism, lymphedema, and painful varicosities following a thigh vascular access graft.

    PubMed

    Thompson, Michael; Mathuram Thiyagarajan, Umasankar; Akoh, Jacob A

    2014-07-01

    Prosthetic arteriovenous grafts (AVGs) are associated with greater morbidity than autogenous arteriovenous fistulas (AVFs), but their use is indicated when AVF formation is not possible. This report adds to the literature a case of lower limb gigantism, painful varicosities, and lymphedema following long-term use of AVG in the upper thigh. The patient's past medical history included renal transplantation on the same side well before the AVG was inserted and right leg deep vein thrombosis. Suspicion of AVG thrombosis was excluded by Doppler ultrasound, which demonstrated an access flow of 1700?mL/min. A computed tomography (CT) scan of the abdomen and pelvis did not identify the cause of her symptoms. Whereas functional incompetence of the iliac vein valve might be responsible for the varicosities, the extent of hypertrophy in this case raises the suspicion of lymphatic blockage possibly secondary to groin dissection undertaken at the time of graft insertion, in addition to the previous dissection at the time of transplantation. This case highlights the need for minimal groin dissection during AVG insertion, particularly in patients with a history of previous abdominopelvic surgery. PMID:24467313

  18. Discovery of gigantic molecular nanostructures using a flow reaction array as a search engine

    PubMed Central

    Zang, Hong-Ying; de la Oliva, Andreu Ruiz; Miras, Haralampos N.; Long, De-Liang; McBurney, Roy T.; Cronin, Leroy

    2014-01-01

    The discovery of gigantic molecular nanostructures like coordination and polyoxometalate clusters is extremely time-consuming since a vast combinatorial space needs to be searched, and even a systematic and exhaustive exploration of the available synthetic parameters relies on a great deal of serendipity. Here we present a synthetic methodology that combines a flow reaction array and algorithmic control to give a chemical ‘real-space’ search engine leading to the discovery and isolation of a range of new molecular nanoclusters based on [Mo2O2S2]2+-based building blocks with either fourfold (C4) or fivefold (C5) symmetry templates and linkers. This engine leads us to isolate six new nanoscale cluster compounds: 1, {Mo10(C5)}; 2, {Mo14(C4)4(C5)2}; 3, {Mo60(C4)10}; 4, {Mo48(C4)6}; 5, {Mo34(C4)4}; 6, {Mo18(C4)9}; in only 200 automated experiments from a parameter space spanning ~5 million possible combinations. PMID:24770632

  19. Respiratory Evolution Facilitated the Origin of Pterosaur Flight and Aerial Gigantism

    PubMed Central

    Claessens, Leon P. A. M.; O'Connor, Patrick M.; Unwin, David M.

    2009-01-01

    Pterosaurs, enigmatic extinct Mesozoic reptiles, were the first vertebrates to achieve true flapping flight. Various lines of evidence provide strong support for highly efficient wing design, control, and flight capabilities. However, little is known of the pulmonary system that powered flight in pterosaurs. We investigated the structure and function of the pterosaurian breathing apparatus through a broad scale comparative study of respiratory structure and function in living and extinct archosaurs, using computer-assisted tomographic (CT) scanning of pterosaur and bird skeletal remains, cineradiographic (X-ray film) studies of the skeletal breathing pump in extant birds and alligators, and study of skeletal structure in historic fossil specimens. In this report we present various lines of skeletal evidence that indicate that pterosaurs had a highly effective flow-through respiratory system, capable of sustaining powered flight, predating the appearance of an analogous breathing system in birds by approximately seventy million years. Convergent evolution of gigantism in several Cretaceous pterosaur lineages was made possible through body density reduction by expansion of the pulmonary air sac system throughout the trunk and the distal limb girdle skeleton, highlighting the importance of respiratory adaptations in pterosaur evolution, and the dramatic effect of the release of physical constraints on morphological diversification and evolutionary radiation. PMID:19223979

  20. Acromegaly and gigantism in the medical literature. Case descriptions in the era before and the early years after the initial publication of Pierre Marie (1886).

    PubMed

    de Herder, Wouter W

    2009-01-01

    In 1886 Pierre Marie used the term "acromegaly" for the first time and gave a full description of the characteristic clinical picture. However several others had already given clear clinical descriptions before him and sometimes had given the disease other names. After 1886, it gradually became clear that pituitary enlargement (caused by a pituitary adenoma) was the cause and not the consequence of acromegaly, as initially thought. Pituitary adenomas could be found in the great majority of cases. It also became clear that acromegaly and gigantism were the same disease but occurring at different stages of life and not different diseases as initially thought. At the end of the 19th and beginning of the 20th century most information was derived from case descriptions and post-mortem examinations of patients with acromegaly or (famous) patients with gigantism. The stage was set for further research into the pathogenesis, diagnosis and therapy of acromegaly and gigantism. PMID:18683056

  1. Increase in tracheal investment with beetle size supports hypothesis of oxygen limitation on insect gigantism.

    PubMed

    Kaiser, Alexander; Klok, C Jaco; Socha, John J; Lee, Wah-Keat; Quinlan, Michael C; Harrison, Jon F

    2007-08-01

    Recent studies have suggested that Paleozoic hyperoxia enabled animal gigantism, and the subsequent hypoxia drove a reduction in animal size. This evolutionary hypothesis depends on the argument that gas exchange in many invertebrates and skin-breathing vertebrates becomes compromised at large sizes because of distance effects on diffusion. In contrast to vertebrates, which use respiratory and circulatory systems in series, gas exchange in insects is almost exclusively determined by the tracheal system, providing a particularly suitable model to investigate possible limitations of oxygen delivery on size. In this study, we used synchrotron x-ray phase-contrast imaging to visualize the tracheal system and quantify its dimensions in four species of darkling beetles varying in mass by 3 orders of magnitude. We document that, in striking contrast to the pattern observed in vertebrates, larger insects devote a greater fraction of their body to the respiratory system, as tracheal volume scaled with mass1.29. The trend is greatest in the legs; the cross-sectional area of the trachea penetrating the leg orifice scaled with mass1.02, whereas the cross-sectional area of the leg orifice scaled with mass0.77. These trends suggest the space available for tracheae within the leg may ultimately limit the maximum size of extant beetles. Because the size of the tracheal system can be reduced when oxygen supply is increased, hyperoxia, as occurred during late Carboniferous and early Permian, may have facilitated the evolution of giant insects by allowing limbs to reach larger sizes before the tracheal system became limited by spatial constraints. PMID:17666530

  2. Optical and radio signatures of negative gigantic jets: Cases from Typhoon Lionrock (2010)

    NASA Astrophysics Data System (ADS)

    Huang, Sung-Ming; Hsu, Rue-Rou; Lee, Li-Jou; Su, Han-Tzong; Kuo, Cheng-Ling; Wu, Chun-Chieh; Chou, Jung-Kuang; Chang, Shu-Chun; Wu, Yen-Jung; Chen, Alfred B.

    2012-08-01

    On 31 August 2010, more than 100 transient luminous events were observed to occur over Typhoon Lionrock when it passed at ˜210 km to the southwest of the NCKU site in Taiwan. Among them, 14 negative gigantic jets (GJs) with clear recognizable morphologies and radio frequency signals are analyzed. These GJs are all found to have negative discharge polarity and thus are type I GJs. Morphologically, they are grouped into three forms: tree-like, carrot-like, and a new intermediate type called tree-carrot-like GJs. The ULF and ELF/VLF band signals of these events contain clear signatures associated with GJ development stages, including the initiating lightning, the leading jet, the fully developed jet, and the trailing jet. Though the radio waveform for each group of GJs always contains a fast descending pulse linked with the surge current upon the GJ-ionosphere contact, the detailed waveforms actually vary substantially. Cross analysis of the optical and radio frequency signals for these GJs indicates that a large surge current moment (CM) (>60 kA-km) appears to be essentially associated with the tree-like GJs. In contrast, the carrot-like and the tree-carrot-like GJs are both related to a surge CM less than 36 kA-km, and a continuing CM less than 27 kA-km further separates the carrot-like GJs from the tree-carrot-like GJs. Furthermore, on the peak CM versus charge moment change diagram for the initiating lightning, different groups of GJs seem to exhibit different trends. This feature suggests that the eventual forms of negative GJs may have been determined at the initiating lightning stage.

  3. Gigantic jets produced by an isolated tropical thunderstorm near Réunion Island

    NASA Astrophysics Data System (ADS)

    Soula, Serge; van der Velde, Oscar; Montanya, Joan; Huet, Patrice; Barthe, Christelle; Bór, József

    2011-10-01

    Five gigantic jets (GJs) have been recorded with video and photograph cameras on 7 March 2010 above an isolated tropical storm east of Réunion Island. Three of them were produced before the storm reached its coldest cloud top temperature (approximately -81°C), and two others occurred during the cloud extension. Thanks to the close distance of observation (˜50 km), the luminosity within the cloud was recorded, and the events are analyzed in unprecedented detail. The tops of the GJs are estimated between 80 and 90 km. All these GJs are accompanied by long, continuous cloud illumination, and they are preceded and followed by intermittent optical flashes from the cloud, most of time without any cloud-to-ground (CG) flash simultaneously detected, which suggests they originated mainly as intracloud discharges and without any charge transfer to Earth. The CG lightning activity is observed to cease a few tens of seconds before the jets. According to ELF data recorded at Nagycenk, Hungary, the five GJs serve to raise negative charge. Their duration ranges from 333 to 850 ms. The leading jet has the most variable duration (33-167 ms) and propagates faster at higher altitudes. The trailing jet exhibits a continuous decrease of luminosity in different parts of the jet (lower channel, transition zone and, for most events, carrot sprite-like top) and in the cloud, with possible rebrightening. The lower channels (˜20-40 km altitude) produce blue luminosity which decreases with altitude and become more and more diffuse with time. The transition zone (around 40-65 km) consists of bright red, luminous beads slowly going up (˜104 m s-1), retracing the initial leading jet channels.

  4. Gigantic landslides versus glacial deposits: on origin of large hummock deposits in Alai Valley, Northern Pamir

    NASA Astrophysics Data System (ADS)

    Reznichenko, Natalya

    2015-04-01

    As glaciers are sensitive to local climate, their moraines position and ages are used to infer past climates and glacier dynamics. These chronologies are only valid if all dated moraines are formed as the result of climatically driven advance and subsequent retreat. Hence, any accurate palaeoenvironmental reconstruction requires thorough identification of the landform genesis by complex approach including geomorphological, sedimentological and structural landform investigation. Here are presented the implication of such approach for the reconstruction of the mega-hummocky deposits formation both of glacial and landslide origin in the glaciated Alai Valley of the Northern Pamir with further discussion on these and similar deposits validity for palaeoclimatic reconstructions. The Tibetan Plateau valleys are the largest glaciated regions beyond the ice sheets with high potential to provide the best geological record of glacial chronologies and, however, with higher probabilities of the numerous rock avalanche deposits including those that were initially considered of glacial origin (Hewitt, 1999). The Alai Valley is the largest intermountain depression in the upper reaches of the Amudarja River basin that has captured numerous unidentified extensive hummocky deposits descending from the Zaalai Range of Northern Pamir, covering area in more than 800 km2. Such vast hummocky deposits are usually could be formed either: 1) glacially by rapid glacial retreat due to the climate signal or triggered a-climatically glacial changes, such as glacial surge or landslide impact, or 2) during the landslide emplacement. Combination of sediment tests on agglomerates forming only in rock avalanche material (Reznichenko et al., 2012) and detailed geomorphological and sedimentological descriptions of these deposits allowed reconstructing the glacial deposition in the Koman and Lenin glacial catchments with identification of two gigantic rock avalanches and their relation to this glacial deposits. Here are presented a new data on: parameters, extent and probable source for Lenin rock avalanche, travelled 24 km from the back wall of the Lenin Glacier over the glacial Achiktash hummock deposit covering more than 35 km2; updated data on Koman rock avalanche deposit, such as its extend and source; the first reconstruction of the Achiktash glacial material deposition with proposed landscape evolution during recent Quaternary in respect to the large landslide in the catchment. Hewitt, K., 1999. Quaternary moraines vs. catastrophic rock avalanches in the Karakoram Himalaya, Northern Pakistan. Quaternary Research, v. 51, p. 220-237. Reznichenko, N.V., Davies, T.R.H., Shulmeister, J. and Larsen S.H, 2012. A new technique for identifying rock-avalanche-sourced sediment in moraines and some paleoclimatic implications. Geology, v. 40, p. 319-322.

  5. System of gigantic valleys northwest of Tharsis, Mars: Latent catastrophic flooding, northwest watershed, and implications for northern plains ocean

    USGS Publications Warehouse

    Dohm, J.M.; Anderson, R.C.; Baker, V.R.; Ferris, J.C.; Hare, T.M.; Strom, R.G.; Rudd, L.P.; Rice, J.W., Jr.; Casavant, R.R.; Scott, D.H.

    2000-01-01

    Mars Orbiter Laser Altimeter (MOLA) reveals a system of gigantic valleys to the northwest of the huge martian shield volcano, Arsia Mons, in the western hemisphere of Mars. These newly identified northwestern slope valleys (NSVs) potentially signify previously undocumented martian catastrophic floods and may corroborate the northern ocean hypotheses. These features, which generally correspond spatially to gravity lows, were previously obscurred in Mariner and Viking Orbiter imagery by veneers of materials, including volcanic lava flows and air fall deposits. Geologic investigations of the Tharsis region suggest that the NSVs were mainly carved prior to the construction of Arsia Mons and its associated Late Hesperian and Amazonian age lava flows, concurrent with the early development of the outflow channels that debouch into Chryse Planitia.

  6. Galls and gall makers in plants from the Pé-de-Gigante Cerrado Reserve, Santa Rita do Passa Quatro, SP, Brazil.

    PubMed

    Urso-Guimarães, M V; Scareli-Santos, C

    2006-02-01

    Thirty-six morphologically different types of galls were obtained in leaves, leaflets, veins, petioles, stems, tendrils and flower buds from twenty-five species of plants in the Pé-de-Gigante Reserve, municipality of Santa Rita do Passa Quatro, state of São Paulo, Brazil. The host plant species belong to the closely related families Anacardiaceae, Annonaceae, Asteraceae, Bignoniaceae, Caryocaraceae, Erythroxylaceae, Fabaceae, Malpighiaceae, Melastomataceae, Myrtaceae, Ochnaceae, Polygalaceae, Sapindaceae, Sapotaceae, and Smilacaceae. The most common gall makers included Cecidomyiidae (Diptera), Pteromalidae (Hymenoptera) and Diaspididae (Sternorrhyncha-Hemiptera). This is the first report of galls found in the following plant genera: Gochnatia (Asteraceae), Distictela (Bignoniaceae), Banisteriopsis (Malpighiaceae), Ouratea (Ochnaceae), and Bredemeyera (Polygalaceae). The results of this work contribute to the body of knowledge about the relationship among host plants, gall makers, and the gall morphology of Pé-de-Gigante Cerrado Reserve. PMID:16710528

  7. Ultrafast gigantic photo-response in charge-ordered organic salt (EDO-TTF)2PF6 on 10-fs time scales

    SciTech Connect

    Itatani, J.; Rini, M.; Cavalleri, A.; Onda, K.; Ishikawa, T.; Ogihara, S.; Koshihara, S.; Shao, X.; Nakano, Y.; Yamochi, H.; Saito, G.; Schoenlein, R.W.

    2008-08-01

    The initial dynamics of photo-induced phase transition in charge-ordered organic salt (EDO-TTF){sub 2}PF{sub 6} was investigated using 10-fs near-infrared laser pulses. We observed sub-20-fs gigantic photo-responses (|{Delta}R/R|>100%) due to intra-molecular vibration and a clear signature of a structural bottleneck ({approx}50 fs) for the first time.

  8. Dust distribution in disks supplied by small bodies: Is the Beta Pictoris disk a gigantic multi-cometary tail?

    E-print Network

    A. Lecavelier des Etangs; A. Vidal-Madjar; R. Ferlet

    1995-08-08

    We have evaluated the spatial distribution of dust in disks supplied by colliding or evaporating bodies spread in a small belt. The gradient of the distribution of dust expelled by radiation pressure is generally steeper than the one observed around \\bp. It follows that, to generate the \\bp\\ disk distribution in such a way, one should extract relatively more small particles in the production process: thanks to radiation forces, these smaller particles have large eccentricities and thus could be seen at very large distances from their injection place. The evaporation process of comet-like bodies moving slowly inwards may yield the necessary particle size distribution. It is interesting to note that this dynamical description is able to account for the main observational properties of the \\bp\\ disk, such as the power law distribution with possibly a change in slope, the asymmetry at large distances, and the total mass, all of which have remained unexplained up to now. If confirmed, this scenario may indicate that the \\bp\\ disk could be looked on as a gigantic multi-cometary tail with its natural constituents: gas and dust.

  9. Gigantic enhancement in the dielectric properties of polymer-based composites using core/shell MWCNT/amorphous carbon nanohybrids

    NASA Astrophysics Data System (ADS)

    Guo, Qikai; Xue, Qingzhong; Sun, Jin; Dong, Mingdong; Xia, Fujun; Zhang, Zhongyang

    2015-02-01

    Novel core/shell structured multi-walled carbon nanotube/amorphous carbon (MWCNT@AC) nanohybrids were successfully prepared using a simple and novel method. Subsequently, the MWCNT@AC nanohybrids were used as fillers to enhance the dielectric properties of poly(vinylidene fluoride) (PVDF) based composites. It is found that the dielectric constant of the MWCNT@AC/PVDF composites can reach 5910 (the dielectric loss is ~2), which is considerably better than that of MWCNT/PVDF composites. The uniform amorphous carbon shell provides an insulative layer between adjacent MWCNTs in the polymer matrix, which not only prevents the direct contact of MWCNTs but also improves the dispersibility of the MWCNTs. Therefore, a surprising number of microcapacitors could be formed in the composites before the formation of a conductive network, leading to a gigantic enhancement in the dielectric properties. Our strategy provides a new approach to fabricate excellent dielectric materials for energy storage capacitors. In addition, the design concept used in this work can be extended to other carbon materials.

  10. Herbivory and Body Size: Allometries of Diet Quality and Gastrointestinal Physiology, and Implications for Herbivore Ecology and Dinosaur Gigantism

    PubMed Central

    Clauss, Marcus; Steuer, Patrick; Müller, Dennis W. H.; Codron, Daryl; Hummel, Jürgen

    2013-01-01

    Digestive physiology has played a prominent role in explanations for terrestrial herbivore body size evolution and size-driven diversification and niche differentiation. This is based on the association of increasing body mass (BM) with diets of lower quality, and with putative mechanisms by which a higher BM could translate into a higher digestive efficiency. Such concepts, however, often do not match empirical data. Here, we review concepts and data on terrestrial herbivore BM, diet quality, digestive physiology and metabolism, and in doing so give examples for problems in using allometric analyses and extrapolations. A digestive advantage of larger BM is not corroborated by conceptual or empirical approaches. We suggest that explanatory models should shift from physiological to ecological scenarios based on the association of forage quality and biomass availability, and the association between BM and feeding selectivity. These associations mostly (but not exclusively) allow large herbivores to use low quality forage only, whereas they allow small herbivores the use of any forage they can physically manage. Examples of small herbivores able to subsist on lower quality diets are rare but exist. We speculate that this could be explained by evolutionary adaptations to the ecological opportunity of selective feeding in smaller animals, rather than by a physiologic or metabolic necessity linked to BM. For gigantic herbivores such as sauropod dinosaurs, other factors than digestive physiology appear more promising candidates to explain evolutionary drives towards extreme BM. PMID:24204552

  11. What lies beneath: sub-articular long bone shape scaling in eutherian mammals and saurischian dinosaurs suggests different locomotor adaptations for gigantism.

    PubMed

    Bonnan, Matthew F; Wilhite, D Ray; Masters, Simon L; Yates, Adam M; Gardner, Christine K; Aguiar, Adam

    2013-01-01

    Eutherian mammals and saurischian dinosaurs both evolved lineages of huge terrestrial herbivores. Although significantly more saurischian dinosaurs were giants than eutherians, the long bones of both taxa scale similarly and suggest that locomotion was dynamically similar. However, articular cartilage is thin in eutherian mammals but thick in saurischian dinosaurs, differences that could have contributed to, or limited, how frequently gigantism evolved. Therefore, we tested the hypothesis that sub-articular bone, which supports the articular cartilage, changes shape in different ways between terrestrial mammals and dinosaurs with increasing size. Our sample consisted of giant mammal and reptile taxa (i.e., elephants, rhinos, sauropods) plus erect and non-erect outgroups with thin and thick articular cartilage. Our results show that eutherian mammal sub-articular shape becomes narrow with well-defined surface features as size increases. In contrast, this region in saurischian dinosaurs expands and remains gently convex with increasing size. Similar trends were observed in non-erect outgroup taxa (monotremes, alligators), showing that the trends we report are posture-independent. These differences support our hypothesis that sub-articular shape scales differently between eutherian mammals and saurischian dinosaurs. Our results show that articular cartilage thickness and sub-articular shape are correlated. In mammals, joints become ever more congruent and thinner with increasing size, whereas archosaur joints remained both congruent and thick, especially in sauropods. We suggest that gigantism occurs less frequently in mammals, in part, because joints composed of thin articular cartilage can only become so congruent before stress cannot be effectively alleviated. In contrast, frequent gigantism in saurischian dinosaurs may be explained, in part, by joints with thick articular cartilage that can deform across large areas with increasing load. PMID:24130690

  12. Darwin's "Gigantic Blunder."

    ERIC Educational Resources Information Center

    Barrett, Paul H.

    1973-01-01

    Darwin's attempt at unraveling the Glen Roy parallel road mystery is discussed. He admitted that Louis Agassiz's glacier theory seemed reasonable but he was reluctant to give up on his own marine theory. (DF)

  13. No More Gigantism

    ERIC Educational Resources Information Center

    Vohra, B. B.

    1975-01-01

    The food situation in India is critical. It requires the development of both land and water resources, both of which are largely untapped. Ground water is one undeveloped resource that can help alleviate the irrigation problems facing agriculture. More efficient utilization could free millions of hectares of land for cultivation. (MA)

  14. A probable case of gigantism/acromegaly in skeletal remains from the Jewish necropolis of "Ronda Sur" (Lucena, Córdoba, Spain; VIII-XII centuries CE).

    PubMed

    Viciano, Joan; De Luca, Stefano; López-Lázaro, Sandra; Botella, Daniel; Diéguez-Ramírez, Juan Pablo

    2015-01-01

    Pituitary gigantism is a rare endocrine disorder caused by hypersecretion of growth hormone during growing period. Individuals with this disorder have an enormous growth in height and associated degenerative changes. The continued hypersecretion of growth hormone during adulthood leads to acromegaly, a condition related to the disproportionate bone growth of the skull, hands and feet. The skeletal remains studied belong to a young adult male from the Jewish necropolis of "Ronda Sur" in Lucena (Córdoba, Spain, VIII-XII centuries CE). The individual shows a very large and thick neurocranium, pronounced supraorbital ridges, an extremely prominent occipital protuberance, and an extremely large and massive mandible. Additional pathologies include enlargement of the vertebral bodies with degenerative changes, thickened ribs, and a slight increased length of the diaphysis with an increased cortical bone thickness of lower limbs. Comparative metric analysis of the mandible with other individuals from the same population and a contemporary Mediterranean population shows a trend toward acromegalic morphology. This case is an important contribution in paleopathological literature because it is a rare condition that has not been widely documented in ancient skeletal remains. PMID:25776010

  15. Gigantism treated by pure endoscopic endonasal approach in a case of McCune-Albright syndrome with sphenoid fibrous dysplasia: a case report.

    PubMed

    Sharifi, Guive; Jalessi, Maryam; Sarvghadi, Farzaneh; Farhadi, Mohammad

    2013-12-01

    McCune-Albright syndrome (MAS) is an uncommon polyostotic manifestation of fibrous dysplasia in association with at least one endocrinopathy that is mostly associated with precocious puberty and hyperpigmented skin macules named café-au-lait spots. We present an atypical manifestation of McCune-Albright syndrome in a 19-year-old man with the uncommon association of polyostotic fibrous dysplasia and gigantism in the absence of café-au-lait spots and precocious puberty. He presented with a height increase to 202 cm in the previous 3 years, which had become more progressive in the few months prior. Physical examination revealed only a mild facial asymmetry; however, a computed tomography (CT) scan discovered vast areas of voluminous bones with ground-glass density and thickening involving the craniofacial bones and skull base. Magnetic resonance imaging (MRI) found a right stalk shift of the pituitary with a 20 mm pituitary adenoma. We describe the diagnostic and endoscopic endonasal transsphenoidal approach for excision of the tumor. PMID:23307306

  16. Gigantic maximum of nanoscale noncontact friction.

    PubMed

    Saitoh, Kohta; Hayashi, Kenichi; Shibayama, Yoshiyuki; Shirahama, Keiya

    2010-12-01

    We report measurements of noncontact friction between surfaces of NbSe2 and SrTiO3 and a sharp Pt-Ir tip that is oscillated laterally by a quartz tuning fork cantilever. At 4.2 K, the friction coefficients on both the metallic and insulating materials show a giant maximum at the tip-surface distance of several nanometers. The maximum is strongly correlated with an increase in the spring constant of the cantilever. These features can be understood phenomenologically by a distance-dependent relaxation mechanism with distributed time scales. PMID:21231483

  17. Gigantic macroautophagy in programmed nuclear death of Tetrahymena thermophila.

    PubMed

    Akematsu, Takahiko; Pearlman, Ronald E; Endoh, Hiroshi

    2010-10-01

    Programmed nuclear death (PND) in Tetrahymena is a unique process during conjugation, in which only the parental macronucleus is degraded and then eliminated from the progeny cytoplasm, but other co-existing nuclei such as new micro- and macronuclei are unaffected. PND through autophagic elimination is expected to be strictly controlled, considering the significant roles in ciliates such as turnover of disused organelles and production of the next generation. Here we demonstrate that PND in Tetrahymena involves peculiar aspects of autophagy, which differ from mammalian or yeast macroautophagy. Drastic change of the parental macronucleus occurs when differentiation of new macronuclei is initiated. Combined use of monodansylcadaverine and a lysosome indicator LysoTracker Red showed that prior to nuclear condensation, the envelope of the parental macronucleus changed its nature as if it is an autophagic membrane, without the accumulation of a pre-autophagosomal structure from the cytoplasm. Subsequently, lysosomes approached only to the parental macronucleus and localized at the envelope until a final resorption stage. In addition, we found that the parental macronucleus exhibits certain sugars and phosphatidylserine on the envelope, which are possible "attack me" signals, that are not found on other types of nuclei. These findings suggest that PND is a highly elaborated process, different from the typical macroautophagy seen in other systems, and is executed through interaction between specific molecular signals on the parental macronuclear envelope and autophagic/lysosomal machineries. PMID:20798592

  18. A gigantic bird from the Upper Cretaceous of Central Asia

    PubMed Central

    Naish, Darren; Dyke, Gareth; Cau, Andrea; Escuillié, François; Godefroit, Pascal

    2012-01-01

    We describe an enormous Late Cretaceous fossil bird from Kazakhstan, known from a pair of edentulous mandibular rami (greater than 275 mm long), which adds significantly to our knowledge of Mesozoic avian morphological and ecological diversity. A suite of autapomorphies lead us to recognize the specimen as a new taxon. Phylogenetic analysis resolves this giant bird deep within Aves as a basal member of Ornithuromorpha. This Kazakh fossil demonstrates that large body size evolved at least once outside modern birds (Neornithes) and reveals hitherto unexpected trophic diversity within Cretaceous Aves. PMID:21835881

  19. A gigantic nothosaur (Reptilia: Sauropterygia) from the Middle Triassic

    E-print Network

    Benton, Michael

    at least by the early Middle Triassic, after the Permian-Triassic mass extinction (PTME). However, indicates global recovery of shallow marine ecosystems from PTME by the early Middle Triassic. T he Permian as extrinsic causes, primarily repeated periods of global warming, ocean acidification and anoxia linked

  20. Glassy protein dynamics and gigantic solvent reorganization energy of plastocyanin

    NASA Astrophysics Data System (ADS)

    Lebard, David; Matyushov, Dmitry

    2008-03-01

    This work focuses on the results of extensive explicit solvent Molecular Dynamics simulations of plastocyanin, a blue copper electron transfer protein involved in natural photosynthesis. Simulation data indicate that low-frequency non-ergodic fluctuations of the protein matrix tethered to the hydrating water are responsible for a very broad distribution of the vertical energy gaps of one-electron protein reduction/oxidation. The width of the corresponding free energy surfaces yields a reorganization free energy far larger than previously reported for any organic, inorganic, or biological chromophores. However, the Stokes shift is not affected by these slow motions and can be calculated from the polarization response function of the dipolar solvent using microscopic solvation models. The glassy nature of the protein-water interface breaks the direct link between the Stokes shift and the reorganization energy from equilibrium (ergodic) electron transfer theories. This suggests a mechanism that accounts for electron transfer in natural proteins, which are characterized by a low reaction free energy combined with a low activation barrier.

  1. Natural Disasters: Explosive Volcanic Eruptions and Gigantic Landslides

    NASA Astrophysics Data System (ADS)

    Huppert, Herbert E.; Brian Dade, W.

    The 1990s have been designated the International Decade of Natural Disaster Reduction; and this paper discusses two natural disasters. In the first we show how to model massive, ground-hugging ash flows, known as pyroclastic flows by geologists, in terms of particle-driven, turbulent gravity currents. A framework for solving forward problems is set up so that, for different geometries, all the flow and deposit properties can be predicted given the initial conditions of the flow following a volcanic eruption. This is then used to discuss inverse problems, for which only the details of the deposit are provided and the initial conditions of the flow are to be calculated. This method of approach is applied to analysing the eruption of Taupo, New Zealand, about 1800 years ago. We demonstrate that the ash-laden flow travelled over the ground in a current of order 1 km high travelling at a typical speed of 200 m s-1. The second study concerns the runout of massive landslides. A model employing the concepts of the flow of granular materials is presented in which the interior of the rockfall propagates uniformly above a thin shear layer of rocks through which all the rocks eventually fall, to leave the flow and add to its deposit. Quantitative predictions from this theoretical model are shown to agree well with observations from about 50 rockslides on Earth, the Moon and Mars. Our model suggests that simulation of such granular flows would be extremely difficult, if not impossible, to achieve in the laboratory.

  2. Acromegalic gigantism, physicians and body snatching. Past or present?

    PubMed

    de Herder, Wouter W

    2012-09-01

    The skeletons of 2 famous acromegalic giants: Charles Byrne (1761-1783) and Henri Cot = Joseph Dusorc (1883-1912) and the embalmed body of the famous acromegalic giant Édouard Beaupré (1881-1904) all ended up in the medical collections of museums despite the fact that these patients had never donated or even refused to donate their corpses, nor had their relatives given permission. The corpse of the acromegalic giant John Aasen (1890-1938) was voluntarily donated to a physician annex collector of trivia from acromegalic giants. The autopsy on the acromegalic giant John Turner (1874-1911) was performed during his funeral ceremony without the relatives being informed. Only recently, the acromegalic giant Alexander Sizonenko (1959-2012) was made a financial offer during his life in exchange for his body after his death. The case-histories of these 6 patients and also the circumstances that led to the (in-) voluntary donation of their bodies are reviewed. PMID:22481633

  3. Gigantic macroautophagy in programmed nuclear death of Tetrahymena thermophila

    PubMed Central

    Pearlman, Ronald E; Endoh, Hiroshi

    2010-01-01

    Programmed nuclear death (PND) in Tetrahymena is a unique process during conjugation, in which only the parental macronucleus is degraded and then eliminated from the progeny cytoplasm, but other co-existing nuclei such as new micro- and macronuclei are unaffected. PND through autophagic elimination is expected to be strictly controlled, considering the significant roles in ciliates such as turnover of disused organelles and production of the next generation. Here we demonstrate that PND in Tetrahymena involves peculiar aspects of autophagy, which differ from mammalian or yeast macroautophagy. Drastic change of the parental macronucleus occurs when differentiation of new macronuclei is initiated. Combined use of monodansylcadaverine and a lysosome indicator LysoTracker Red showed that prior to nuclear condensation, the envelope of the parental macronucleus changed its nature as if it is an autophagic membrane, without the accumulation of a pre-autophagosomal structure from the cytoplasm. Subsequently, lysosomes approached only to the parental macronucleus and localized at the envelope until a final resorption stage. In addition, we found that the parental macronucleus exhibits certain sugars and phosphatidylserine on the envelope, which are possible “attack me” signals, that are not found on other types of nuclei. These findings suggest that PND is a highly elaborated process, different from the typical macroautophagy seen in other systems, and is executed through interaction between specific molecular signals on the parental macronuclear envelope and autophagic/lysosomal machineries. PMID:20798592

  4. Evolutionary adaptations of birds to gigantism Student project category: master project

    E-print Network

    Uppsala Universitet

    occurred in the avian phylogeny independently and many times, the origin of giant birds rarely broke maximus) from Madagascar. The evolutionary pathway of these flightless birds was terminated by humans several centuries ago, but the story "where did they come from? and "how did they turn into giants

  5. Gigantism in honeybees: Apis cerana queens reared in mixed-species colonies

    NASA Astrophysics Data System (ADS)

    Tan, Ken; Hepburn, H. R.; He, Shaoyu; Radloff, S. E.; Neumann, P.; Fang, Xiang

    2006-07-01

    The development of animals depends on both genetic and environmental effects to a varying extent. Their relative influences can be evaluated in the social insects by raising the intracolonial diversity to an extreme in nests consisting of workers from more than one species. In this study, we studied the effects of mixed honeybee colonies of Apis mellifera and Apis cerana on the rearing of grafted queen larvae of A. cerana. A. mellifera sealed worker brood was introduced into A. cerana colonies and on emergence, the adults were accepted. Then, A. cerana larvae were grafted for queen rearing into two of these mixed-species colonies. Similarly, A. cerana larvae and A. mellifera larvae were also grafted conspecifically as controls. The success rate of A. cerana queen rearing in the test colonies was 64.5%, surpassing all previous attempts at interspecific queen rearing. After emergence, all virgin queens obtained from the three groups ( N=90) were measured morphometrically. The A. cerana queens from the mixed-species colonies differed significantly in size and pigmentation from the A. cerana control queens and closely approximated the A. mellifera queens. It is inferred that these changes in the A. cerana queens reared in the mixed-species colonies can be attributed to feeding by heterospecific nurse bees and/or chemical differences in royal jelly. Our data show a strong impact of environment on the development of queens. The results further suggest that in honeybees the cues for brood recognition can be learned by heterospecific workers after eclosion, thereby providing a novel analogy to slave making in ants.

  6. Parallel gigantism and complex colonization patterns in the Cape Verde scincid lizards Mabuya and

    E-print Network

    Carranza, Salvador

    not developed earlier or because colonization cut across the path of the Canary Current and the Northeast Trade-living animals formally reported being seen by Alexander (1898) and Fea (1898). On present evidence Mabuya has

  7. Linker Chains of the Gigantic Hemoglobin of the Earthworm Lumbricus terrestris: Primary Structures of

    E-print Network

    Riggs, Austen

    with the seven ligand-binding repeats of the human low-density lipoprotein recep- tor (LDLR). Analysis of linker L1 shows that the connectivity of the three disulfide bonds is exactly the same as in the LDLR residues in both the LDLR repeats and in the linkers supports the sugges- tion that calcium is required

  8. Molecular systematics and phylogeography of the gigantic earthworms of the Metaphire formosae species group (Clitellata, Megascolecidae).

    PubMed

    Chang, Chih-Han; Lin, Si-Min; Chen, Jiun-Hong

    2008-12-01

    The earthworms of the Metaphire formosae species group distributed in Taiwan are members of the Pheretima complex within the Megascolecidae. In this study, the systematics and phylogeography of this species group were investigated using DNA sequences of mitochondrial cytochrome c oxidase subunit I (COI), 16S ribosomal (r)RNA, and NADH dehydrogenase subunit 1 (ND1). The results indicated that the 13 taxa of the M. formosae species group form a clade, including a cryptic species discovered in this study. In addition, Metaphire hengchunensis (James, S.W., Shih, H.-T., Chang, H.-W., 2005. Seven new species of Amynthas (Clitellata: Megascolecidae) and new earthworm records from Taiwan. J. Nat. Hist. 39, 1007-1028) should be regarded as a subspecies of Metaphire paiwanna Tsai, C.-F., Shen, H.-P., Tsai, S.-C., 2000a. Native and exotic species of terrestrial earthworm (Oligochaeta) in Taiwan with reference to Northeast Asia. Zool. Stud. 39, 285-294, Tsai, C.-F., Tsai, S.-C., Liaw, G.-J., 2000b. Two new species of pontandric pheretimoid earthworms belonging to the genus Metaphire (Megascolecidae: Oligochaeta) from Taiwan. J. Nat. Hist. 34, 1731-1741, and Metaphire bununa glareosa Tsai et al. 2000 should be elevated to specific status. Phylogeographical inferences showed that allopatric speciation occurred in this species group during the rapid uplift of the main island of Taiwan between 5.0 and 2.5 million years ago. Our analysis exposes non-monophyly within each of the genera Amynthas and Metaphire, and more generally within the Pheretima complex. Further revisions of this speciose complex are urgently needed. PMID:18809504

  9. Gigantic unruptured sinus of Valsalva aneurysm presenting as an incidental murmur.

    PubMed

    Yagoub, Hatim; Srinivas, Bhanu Prakash; McCarthy, James; Kiernan, Thomas John

    2012-01-01

    We report a case of a 56-year-old man referred by his family physician with an asymptomatic cardiac murmur. Trans-thoracic echocardiography (TTE) suggested an unruptured right sinus of Valsalva aneurysm (SVA) causing extrinsic compression of the right ventricular outflow tract. This was confirmed with an ECG-gated cardiac CT showing a large right SVA measuring 35×37×42 mm in size. Coronary angiography demonstrated non-obstructive coronary artery disease. Ascending thoracic anterior in the right anterior oblique view delineated the right SVA. The patient underwent aortic valve sparing surgical repair of the aneurysm with an excellent result. Echocardiography confirmed obliteration of the aneurysm and normal aortic valve function postoperatively. PMID:23008378

  10. The Battle of the Pronouns: Gigantic Clashes in a Book of Dinasaur Riddles.

    ERIC Educational Resources Information Center

    Sterne, Noelle

    1981-01-01

    The author of "Tyrannosaurus Wrecks: A Book of Dinosaur Riddles" discusses her difficulties in choosing appropriate male-female pronouns for the subjects of her riddles. The problems consisted of the necessity of using entrenched male stereotypes, avoiding damaging female stereotypes, and breaking through stereotypes. (KC)

  11. Occurrence of gigantic biogenic magnetite during the Paleocene-Eocene Thermal Maximum

    NASA Astrophysics Data System (ADS)

    Schumann, D.; Raub, T. D.; Kopp, R. E.; Guerquin-Kern, J. L.; Wu, T. D.; Rouiller, I.; Smirnov, A. V.; Sears, S. K.; Lücken, U.; Tikoo, S. M.; Hesse, R.; Kirschvink, J. L.; Vali, H.

    2009-04-01

    The Paleocene-Eocene Thermal Maximum (PETM) is one of the most severe climatic events of the Cenozoic Era. A massive injection of light carbon into the oceans and atmosphere over a few thousand of years triggered drastic perturbation of Earth's climate resulting in abrupt global warming of ~5-9oC [Sluijs et al., 2007] that persisted for ~180,000 years. This episode is marked by the diversification and radiation of terrestrial plants and mammals while in the marine realm numerous deep-sea benthic foraminifera species disappeared and new forms evolved. Sediments deposited during the PETM are clay-rich and contain distinct evidence of these climatic changes. Kopp et al., (2007) and Lippert & Zachos (2007) report an extraordinary magnetofossil ‘Lagerstätte' in lowermost Eocene kaolinite-rich clay sediments deposited at subtropical paleolatitude in the Atlantic Coastal Plain of New Jersey, USA. Magnetofossils are magnetic particles produced most abundantly by magnetotactic bacteria. Kopp et al. (2007) and Lippert & Zachos (2007) used ferromagnetic resonance (FMR) spectroscopy, other rock magnetic methods, and transmission electron microscopy (TEM) of magnetic separates to characterize sediments from boreholes at Ancora (ODP Leg 174AX) and Wilson Lake, NJ, respectively. These sediments contain abundant ~40- to 300-nm cuboidal, elongate-prismatic and bullet-shaped magnetofossils, sometimes arranged in short chains, resembling crystals in living magnetotactic bacteria. Despite the scarcity of intact magnetofossil chains, the asymmetry ratios of the FMR spectra reflects a profusion of elongate single domain (SD) crystals and/or chains. Here we address both conundrums by reporting the discovery from these same sediments of exceptionally large and novel biogenic magnetite crystals unlike any previously reported from living organisms or from sediments. Aside from abundant bacterial magnetofossils, electron microscopy reveals novel spearhead-like and spindle-like magnetite crystals up to 4 ?m long (eight times larger than magnetite produced by magnetotactic bacteria) and elongated hexaoctahedra up to 1.4 ?m long. Similar to magnetite produced by magnetotactic bacteria, these single-crystal particles exhibit chemical composition and lattice perfection consistent with a biogenic origin. The oxygen isotopic composition of indiviual particles supports a low temperature aquatic origin. Electron holography indicates single-domain magnetization despite the large crystal size. In a few cases, we observed apparently intact, tip-outward spherical assemblages of spearhead-like particles that possibly represent the preserved original biological arrangement of these crystals in a hitherto unknown magnetite producing organism. The discovery of these exceptionally large biogenic magnetite crystals that possibly represent the remains of a new microorganism that appeared and disappeared with the PETM sheds some light upon the ecological response to biogeochemical changes that occurred during this warming event. The abundance of fossil magnetotactic bacteria on the Atlantic Coastal Plain during the PETM could be explained by enhanced production, enhanced preservation, or both. The presence of novel magnetofossils, however, argues that changes in growth conditions are a major part of the explanation. Considering that other bacterial magnetofossils are present (although less abundant) and well-preserved in sediments below and above the PETM clay, as well as in a sand lens within the PETM clay [Kopp et al., 2007], suggests that the new magnetofossils are unlikely to be a preservation artefact. We conclude, therefore, that the development of a thick suboxic zone with high iron bioavailability - a product of dramatic changes in weathering and sedimentation patterns driven by severe global warming - resulted in diversification of magnetite-forming organisms, likely including eukaryotes. In this study we extended the search for these new magnetofossils [Schumann et al. 2008] to other PETM locations of the Atlantic margin and to a possible modern

  12. Great Earthquakes, Gigantic Landslides, and the Continuing Enigma of the April Fool's Tsunami of 1946

    NASA Astrophysics Data System (ADS)

    Fryer, G. J.; Tryon, M. D.

    2005-12-01

    Paleotsunami studies can extend the record of great earthquakes back into prehistory, but what if the historical record itself is ambiguous? There is growing controversy about whether great earthquakes really occur along the Shumagin and Unimak segments of the Alaska-Aleutian system. The last great tsunami there was April 1, 1946, initiated by an earthquake whose magnitude has variously been reported from 7.1 to 8.5. Okal et al (BSSA, 2003) surveyed the near-field runup and concluded there were two sources: a magnitude 8.5 earthquake, which generated a Pacific-wide tsunami but which produced near-field runups no more than 18 m, and an earthquake-triggered slump whose tsunami reached 42 m at Scotch Cap Light near the western end of Unimak Island, but with runup rapidly decaying eastwards. An M8.5 earthquake, however, is incompatible with GPS strain measurements, which indicate that the maximum earthquake size off Unimak is M7.5. We have long contended that near- and far-field tsunamis were the result of a single earthquake-triggered debris avalanche down the Aleutian slope. In 2004 we were part of an expedition to map and explore the landslide, whose location seemed to be very tightly constrained by the known tsunami travel time to Scotch Cap Light. We found that neither our giant landslide nor Okal et al's smaller slump exist within 100 km of the presumed location. The explanation is obvious in retrospect: the tsunami was so large that it crossed the shallow Aleutian shelf as a bore travelling faster than the theoretical long-wave speed (which we had used to fix the location). Any landslide could only have occurred in an unsurveyed area farther east, off Unimak Bight, the central coast of Unimak Island. That location, however, conflicts with Okal et al's measurements of smaller runup along the Bight. We are now convinced that Okal et al confused the 1946 debris line with the lower line left by the 1957 tsunami. They were apparently unaware that the 1946 tsunami also destroyed an unmanned light on the rocky promontary of Cape Pankof, the eastern tip of Unimak Island. From photographs and pre-1946 charts, we have determined that the 1946 runup at Cape Pankof must have exceeded 25 m, a value that is incompatible with Okal et al's field measurements. We cannot avoid the conclusion that both near-field and far-field tsunamis had the same source. If the source was a great M8.5 earthquake, then the geodetic measurements from one earthquake cycle cannot be applied to another. In light of the Indian Ocean Tsunami, however, the huge runup at Scotch Cap can no longer be regarded as a problem for an earthquake source, since runups in Sumatra last December were also far larger than expected. If, on the other hand, the source was a debris avalanche, it can only have occurred in the unsurveyed region. To satisfy the timing constraints, the tsunami had to be so large that the leading bore crossed the shelf with a Froude number of at least 2. The only way to make such a large tsunami is with an immense debris avalanche of over 200 km3. Such an avalanche is quite capable of explaining the far-field observations. To solve the enigma we shall have to complete the mapping of the upper Aleutian forearc, resurvey the near-field runup knowing that the area was also affected by the 1957 tsunami, and run push-core transects across the lowlands of Unimak Bight.

  13. Gigantism in unique biogenic magnetite at the Paleocene–Eocene Thermal Maximum

    PubMed Central

    Schumann, Dirk; Raub, Timothy D.; Kopp, Robert E.; Guerquin-Kern, Jean-Luc; Wu, Ting-Di; Rouiller, Isabelle; Smirnov, Aleksey V.; Sears, S. Kelly; Lücken, Uwe; Tikoo, Sonia M.; Hesse, Reinhard; Kirschvink, Joseph L.; Vali, Hojatollah

    2008-01-01

    We report the discovery of exceptionally large biogenic magnetite crystals in clay-rich sediments spanning the Paleocene–Eocene Thermal Maximum (PETM) in a borehole at Ancora, NJ. Aside from previously described abundant bacterial magnetofossils, electron microscopy reveals novel spearhead-like and spindle-like magnetite up to 4 ?m long and hexaoctahedral prisms up to 1.4 ?m long. Similar to magnetite produced by magnetotactic bacteria, these single-crystal particles exhibit chemical composition, lattice perfection, and oxygen isotopes consistent with an aquatic origin. Electron holography indicates single-domain magnetization despite their large crystal size. We suggest that the development of a thick suboxic zone with high iron bioavailability—a product of dramatic changes in weathering and sedimentation patterns driven by severe global warming—drove diversification of magnetite-forming organisms, likely including eukaryotes. PMID:18936486

  14. Gigantism in unique biogenic magnetite at the PaleoceneEocene Thermal Maximum

    E-print Network

    Kirschvink, Joseph L.

    Boulevard, Pasadena, CA 91125; dDepartment of Geosciences and Woodrow Wilson School of Public,b , Timothy D. Raubc , Robert E. Koppd , Jean-Luc Guerquin-Kerne,f , Ting-Di Wue,f , Isabelle Rouillerb sediments from boreholes at Ancora (ODP Leg 174AX) (Fig. 1) and Wilson Lake, NJ, respectively

  15. Cryptococcus neoformans Capsular Enlargement and Cellular Gigantism during Galleria mellonella Infection

    PubMed Central

    García-Rodas, Rocío; Casadevall, Arturo; Rodríguez-Tudela, Juan Luís; Cuenca-Estrella, Manuel; Zaragoza, Oscar

    2011-01-01

    We have studied infection of Cryptococcus neoformans in the non-vertebrate host Galleria mellonella with particular interest in the morphological response of the yeast. Inoculation of C. neoformans in caterpillars induced a capsule-independent increase in haemocyte density 2 h after infection. C. neoformans manifested a significant increase in capsule size after inoculation into the caterpillar. The magnitude of capsule increase depended on the temperature, being more pronounced at 37°C than at 30°C, which correlated with an increased virulence of the fungus and reduced phagocytosis at 37°C. Capsule enlargement impaired phagocytosis by haemocytes. Incubation of the yeast in G. mellonella extracts also resulted in capsule enlargement, with the polar lipidic fraction having a prominent role in this effect. During infection, the capsule decreased in permeability. A low proportion of the cells (<5%) recovered from caterpillars measured more than 30 µm and were considered giant cells. Giant cells recovered from mice were able to kill the caterpillars in a manner similar to regular cells obtained from in vivo or grown in vitro, establishing their capacity to cause disease. Our results indicate that the morphological transitions exhibited by C. neoformans in mammals also occur in a non-vertebrate host system. The similarities in morphological transitions observed in different animal hosts and in their triggers are consistent with the hypothesis that the cell body and capsular responses represent an adaptation of environmental survival strategies to pathogenesis. PMID:21915338

  16. Maintaining epithelial integrity: a function for gigantic spectraplakin isoforms in adherens junctions.

    PubMed

    Röper, Katja; Brown, Nicholas H

    2003-09-29

    The Short stop (Shot/Kakapo) spectraplakin is a giant cytoskeletal protein, which exists in multiple isoforms with characteristics of both spectrin and plakin superfamilies. Previously characterized Shot isoforms are similar to spectrin and dystrophin, with an actin-binding domain followed by spectrin repeats. We describe a new large exon within the shot locus, which encodes a series of plakin repeats similar to the COOH terminus of plakins such as plectin and BPAG1e. We find that the plakin repeats are inserted between the actin-binding domain and spectrin repeats, generating isoforms as large as 8,846 residues, which could span 400 nm. These novel isoforms localized to adherens junctions of embryonic and follicular epithelia. Loss of Shot within the follicle epithelium leads to double layering and accumulation of actin and ZO-1 in between, and a reduction of Armadillo and Discs lost within, mutant cells, indicative of a disruption of adherens junction integrity. Thus, we identify a new role for spectraplakins in mediating cell-cell adhesion. PMID:14517208

  17. Unigas readies for motor fuel surge with supplies from gigantic plant

    SciTech Connect

    Not Available

    1992-10-01

    Nestled away a short distance from the smog and congestion of Mexico City is a sprawling LP-gas plant from which 72 million gallons of propane are shipped annually. Boasting a storage capacity of 865,000 gal. in 19 tanks, this plant is believed to possess the largest total reserve capacity of any such facility south of the border and in all of Latin America. This paper reports on a tour of the Unigas plant in Ixhuatepec, hosted by general director Carlos Venegas Baeza, which provides insight into three major areas: the operations and plans of one of the largest LP-gas companies in Mexico, the booming market in carburetion, and most noteworthy, the technologically advanced safety/security system that has been installed at this point.

  18. Low levels of LTR retrotransposon deletion by ectopic recombination in the gigantic genomes of salamanders.

    PubMed

    Frahry, Matthew Blake; Sun, Cheng; Chong, Rebecca A; Mueller, Rachel Lockridge

    2015-02-01

    Across the tree of life, species vary dramatically in nuclear genome size. Mutations that add or remove sequences from genomes-insertions or deletions, or indels-are the ultimate source of this variation. Differences in the tempo and mode of insertion and deletion across taxa have been proposed to contribute to evolutionary diversity in genome size. Among vertebrates, most of the largest genomes are found within the salamanders, an amphibian clade with genome sizes ranging from ~14 to ~120 Gb. Salamander genomes have been shown to experience slower rates of DNA loss through small (i.e., <30 bp) deletions than do other vertebrate genomes. However, no studies have addressed DNA loss from salamander genomes resulting from larger deletions. Here, we focus on one type of large deletion-ectopic-recombination-mediated removal of LTR retrotransposon sequences. In ectopic recombination, double-strand breaks are repaired using a "wrong" (i.e., ectopic, or non-allelic) template sequence-typically another locus of similar sequence. When breaks occur within the LTR portions of LTR retrotransposons, ectopic-recombination-mediated repair can produce deletions that remove the internal transposon sequence and the equivalent of one of the two LTR sequences. These deletions leave a signature in the genome-a solo LTR sequence. We compared levels of solo LTRs in the genomes of four salamander species with levels present in five vertebrates with smaller genomes. Our results demonstrate that salamanders have low levels of solo LTRs, suggesting that ectopic-recombination-mediated deletion of LTR retrotransposons occurs more slowly than in other vertebrates with smaller genomes. PMID:25608479

  19. A Gigantic Shark from the Lower Cretaceous Duck Creek Formation of Texas

    PubMed Central

    Frederickson, Joseph A.; Schaefer, Scott N.; Doucette-Frederickson, Janessa A.

    2015-01-01

    Three large lamniform shark vertebrae are described from the Lower Cretaceous of Texas. We interpret these fossils as belonging to a single individual with a calculated total body length of 6.3 m. This large individual compares favorably to another shark specimen from the roughly contemporaneous Kiowa Shale of Kansas. Neither specimen was recovered with associated teeth, making confident identification of the species impossible. However, both formations share a similar shark fauna, with Leptostyrax macrorhiza being the largest of the common lamniform sharks. Regardless of its actual identification, this new specimen provides further evidence that large-bodied lamniform sharks had evolved prior to the Late Cretaceous. PMID:26039066

  20. Vulvar defect after pelvic trauma and its repair with reverse TRAM flap: report of a case.

    PubMed

    Mousavi, S R; Mahdikhah, Z

    2014-01-01

    Vulvar defect and soft tissue loss secondary to pelvic trauma is rare. Many reconstructive procedures for large vulvoperineal defects have been described. The case of a woman with severe vulvar defect following a previous pelvic trauma and treatment with reverse TRAM flap is reported. PMID:25073216

  1. Swift follow-up of the gigantic TeV outburst of PKS 2155-304 in 2006

    E-print Network

    Foschini, L; Tavecchio, F; Treves, A; Maraschi, L; Gliozzi, M; Raiteri, C M; Villata, M; Pian, E; Tagliaferri, G; Tosti, G; Sambruna, R M; Malaguti, G; Di Cocco, G; Giommi, P

    2007-01-01

    At the end of July 2006, the blazar PKS 2155-304 (z=0.116) underwent a strong outburst observed at TeV energies by HESS (up to 17 Crab flux level at E > 200 GeV). The Swift satellite followed the evolution of the source for about one month. The data analysis - reported in another paper - has shown that, despite the violent activity at TeV energies, the synchrotron energy distribution increased in normalization, but only with a small shift in frequency. In the present work, we fit the broad-band spectrum with a log-parabolic model, to search for indications of intrinsic curvature, which in turn is usually interpreted as a signature of energy-dependent acceleration mechanisms of electrons.

  2. "A Gigantic Pedagogical Leap": The Process of Shifts during Three Learning Study Projects in Swedish Early Childhood Education

    ERIC Educational Resources Information Center

    Ljung-Djärf, Agneta; Wennås Brante, Eva; Holmqvist Olander, Mona

    2014-01-01

    Swedish early childhood education (ECE) offers a curriculum-based preschool for children aged one to five, and a preschool class for children aged six years. Activities in these programs have traditionally been based on play and having fun, avoiding structured activities with formal learning objectives. Due to indications that Swedish ECE has…

  3. Oceanic ecosystem dynamics during gigantic volcanic episodes: the Ontong Java and Manihiki Plateaus recorded by calcareous nannoplankton. (Invited)

    NASA Astrophysics Data System (ADS)

    Erba, E.

    2010-12-01

    Earth's volcanic activity introduces environmental stress that biota are forced to survive. There is a general consensus on the role of volcanogenic carbon dioxide increases, and implicit tectonic-igneous events, triggering major climate changes and profound variations in chemical, physical and trophic characteristics of the oceans through the Phanerozoic. Cretaceous geological records indicate conditions of excess atmCO2 (up to 2000-3000 ppm) derived from construction of Large Igneous Provinces (LIPs). In such “high CO2 world” and greenhouse conditions, the deep ocean became depleted of oxygen promoting the accumulation and burial of massive amounts of organic matter; such episodes are recognized as Oceanic Anoxic Events (OAEs) and their geological records merit careful examination of how the Earth system, and Life in particular, can overcome extreme experiments of global change. The Early Aptian (˜ 120 million years ago) OAE1a is a complex example of volcanicCO2-induced environmental stress. There is a general consensus on the causes of this case-history, namely excess CO2 derived from the construction of the Ontong Java-Manihiki LIP. Multi- and inter-disciplinary studies of the OAE1a have pointed out C, O, Os, Sr isotopic anomalies, a biocalcification crisis in pelagic and neritic settings, enhanced fertility and primary productivity, as well as ocean acidification. Available cyclochronology allows high-resolution dating of biotic and environmental fluctuations, providing the precision necessary for understanding the role of volcanogenic CO2 on nannoplankton biocalcification, adaptations, evolutionary innovation and/or extinctions. The reconstructed sequence of volcanogenic CO2 pulses, and perhaps some clathrate melting, triggered a climate change to supergreenhouse conditions, anoxia and ocean acidification. The demise of heavily calcified nannoconids and reduced calcite paleofluxes marks beginning of the pre-OAE1a calcification crisis. Ephemeral coccolith dwarfism and malformation represent adjustments to survive lower pH. Deep-water acidification occurs with a delay of 25-30 thousand years: a dissolution event recording 1 to 2km shallowing of the Calcite Compensation Depth anticipated the onset of anoxic sedimentation. A major acceleration in weathering has been identified in the lowermost part of OAE1a. After acidification-dissolution climax, nannoplankton and carbonate recovery developed over ~160 kyr, under persisting global dysoxia-anoxia. This recovery presumably implies a stasis of the LIP activity and gradual buffering of ocean acidification or a decrease in volcanogenic CO2 emissions and consistently higher CO2 drawdown through Corg burial and/or weathering. Rising CO2 and surface-ocean acidification during OAE1a triggered false extinctions among calcareous nannoplankton. Conversely, a major origination episode starts approximately 1 My before global anoxia and persists through OAE1a and associated acidification. Increasing pCO2 caused complex and species-specific reactions, including production of r-strategist taxa, which, however, secreted dwarf and malformed coccoliths as a strategy to overcome acidification.

  4. A gigantic X-ray flare from the star Trumpler 14 Y442 in the Carina star forming complex

    NASA Astrophysics Data System (ADS)

    Hamaguchi, Kenji; Drake, Stephen A.; Corcoran, Michael F.; Richardson, Noel; Teodoro, Mairan

    2015-09-01

    XMM-Newton, NuSTAR and Swift observations of the Carina star forming complex on 2015 July 16 (ObsID - XMM:0762910401, NuSTAR:30101005002, Swift:00081578001) detected an X-ray flare at the coordinates (R.A., Dec)[J2000] = (10 44 02.80, -59 39 46.7).

  5. Climate warming and stability of cold hanging glaciers: Lessons from the gigantic 1895 Altels break-off

    E-print Network

    Faillettaz, Jerome; Funk, Martin

    2011-01-01

    The Altels hanging glacier broke off on September 11, 1895. The ice volume of this catastrophic rupture was estimated at $\\rm 4.10^6$ cubic meters and is the largest ever observed ice fall event in the Alps. The causes of this collapse are however not entirely clear. Based on previous studies, we reanalyzed this break-off event, with the help of a new numerical model, initially developed by Faillettaz and others (2010) for gravity-driven instabilities. The simulations indicate that a break-off event is only possible when the basal friction at the bedrock is reduced in a restricted area, possibly induced by the storage of infiltrated water within the glacier. Moreover, our simulations reveal a two-step behavior: (i) A first quiescent phase, without visible changes, with a duration depending on the rate of basal changes; (ii) An active phase with a rapid increase of basal motion over a few days. The general lesson obtained from the comparison between the simulations and the available evidence is that visible si...

  6. Inteligncia Artificial Gigantes tecnolgicos como a Google e o Facebook apostam tudo na criao de programas que consigam aprender, conversar

    E-print Network

    Instituto de Sistemas e Robotica

    - tha, dotado de inteligência e capaz de aprender com a experiência, dialogar, dizer piadas e até a ficção, com siste- mas operativos dotados não apenas de inteligência e voz, mas também de uma "presença

  7. A gigantic sarcopterygian (tetrapodomorph lobe-finned fish) from the upper Devonian of Gondwana (Eden, New South Wales, Australia).

    PubMed

    Young, Ben; Dunstone, Robert L; Senden, Timothy J; Young, Gavin C

    2013-01-01

    Edenopteron keithcrooki gen. et sp. nov. is described from the Famennian Worange Point Formation; the holotype is amongst the largest tristichopterids and sarcopterygians documented by semi-articulated remains from the Devonian Period. The new taxon has dentary fangs and premaxillary tusks, features assumed to be derived for large Northern Hemisphere tristichopterids (Eusthenodon, Hyneria, Langlieria). It resembles Eusthenodon in ornament, but is distinguished by longer proportions of the parietal compared to the post-parietal shield, and numerous differences in shape and proportions of other bones. Several characters (accessory vomers in the palate, submandibulars overlapping ventral jaw margin, scales ornamented with widely-spaced deep grooves) are recorded only in tristichopterids from East Gondwana (Australia-Antarctica). On this evidence Edenopteron gen. nov. is placed in an endemic Gondwanan subfamily Mandageriinae within the Tristichopteridae; it differs from the nominal genotype Mandageria in its larger size, less pointed skull, shape of the orbits and other skull characters. The hypothesis that tristichopterids evolved in Laurussia and later dispersed into Gondwana, and a derived subgroup of large Late Devonian genera dispersed from Gondwana, is inconsistent with the evidence of the new taxon. Using oldest fossil and most primitive clade criteria the most recent phylogeny resolves South China and Gondwana as areas of origin for all tetrapodomorphs. The immediate outgroup to tristichopterids remains unresolved - either Spodichthys from Greenland as recently proposed, or Marsdenichthys from Gondwana, earlier suggested to be the sister group to all tristichopterids. Both taxa combine two characters that do not co-occur in other tetrapodomorphs (extratemporal bone in the skull; non-cosmoid round scales with an internal boss). Recently both 'primitive' and 'derived' tristichopterids have been discovered in the late Middle Devonian of both hemispheres, implying extensive ghost lineages within the group. Resolving their phylogeny and biogeography will depend on a comprehensive new phylogenetic analysis. PMID:23483884

  8. Gigantic Ordovician volcanic ash fall in North America and Europe: Biological, tectonomagmatic, and event-stratigraphic significance

    SciTech Connect

    Huff, W.D. ); Bergstroem, S.M. ); Kolata, D.R. )

    1992-10-01

    Biostratigraphical, geochemical, isotopic, and paleogeographic data suggest that the Millbrig K-bentonite, one of the thickest and most widespread Ordovician volcanic ash beds in eastern North America, is the same as the so-called 'Big Bentonite' in Baltoscandia. This is the first time that the same K-bentonite has been identified in both North America and Europe, and it serves as a unique event-stratigraphic marker over a large portion of the Northern Hemisphere. This eruption produced at least 340 km[sup 3] of dense-rock-equivalent ash that was deposited in a layer up to 1-2 m thick over several million square kilometers. As much as 800 km[sup 3] of additional ash may have fallen into the Iapetus Ocean, for a total of 1,140 km[sup 3]. Trace element geochemistry shows that the ash was derived from a felsic calc-alkalic magmatic source characteristic of volcanism in a continental crust-based, destructive plate-margin setting. This is one of the largest, if not the largest, ash falls recorded in Earth's Phanerozoic stratigraphic record, but its recognizable effect on faunas and floras was minimal, and it did not result in a global extinction event. The Millbrig-Big Bentonite bed provides accurate time control for sedimentologic, paleoecologic, and paleogeographic reconstructions across plates positioned in tropical (Laurentia) and temperate (Baltica) latitudes during Middle Ordovician time.

  9. Gigantism in a Bacterium, Epulopiscium fishelsoni, Correlates with Complex Patterns in Arrangement, Quantity, and Segregation of DNA

    PubMed Central

    Bresler, V.; Montgomery, W. L.; Fishelson, L.; Pollak, P. E.

    1998-01-01

    Epulopiscium fishelsoni, gut symbiont of the brown surgeonfish (Acanthurus nigrofuscus) in the Red Sea, attains a larger size than any other eubacterium, varies 10- to 20-fold in length (and >2,000-fold in volume), and undergoes a complex daily life cycle. In early morning, nucleoids contain highly condensed DNA in elongate, chromosome-like structures which are physically separated from the general cytoplasm. Cell division involves production of two (rarely three) nucleoids within a cell, deposition of cell walls around expanded nucleoids, and emergence of daughter cells from the parent cell. Fluorescence measurements of DNA, RNA, and other cell components indicate the following. DNA quantity is proportional to cell volume over cell lengths of ?30 ?m to >500 ?m. For cells of a given size, nucleoids of cells with two nucleoids (binucleoid) contain approximately equal amounts of DNA. And each nucleoid of a binucleoid cell contains one-half the DNA of the single nucleoid in a uninucleoid cell of the same size. The life cycle involves approximately equal subdivision of DNA among daughter cells, formation of apical caps of condensed DNA from previously decondensed and diffusely distributed DNA, and “pinching” of DNA near the middle of the cell in the absence of new wall formation. Mechanisms underlying these patterns remain unclear, but formation of daughter nucleoids and cells occurs both during diurnal periods of host feeding and bacterial cell growth and during nocturnal periods of host inactivity when mean bacterial cell size declines. PMID:9791108

  10. Dual electron-phonon coupling model for gigantic photoenhancement of the dielectric constant and electronic conductivity in SrTi O3

    NASA Astrophysics Data System (ADS)

    Qiu, Y.; Wu, C. Q.; Nasu, K.

    2005-12-01

    In connection with the recent experimental discovery on photoenhancements of the electronic conductivity and the quasi-static electric susceptibility in SrTiO3 , we theoretically study a photogeneration mechanism of charged and conductive ferroelectric domains in this perovskite type quantum dielectric. The photo-generated electron, being quite itinerant in the 3d band of Ti4+ , is assumed to couple weakly but quadratically with soft-anharmonic T1u phonons in this quantum dielectric, in view of the parity of this lattice vibration. The photo-generated electron is also assumed to couple strongly but linearly with the breathing type high energy phonons. Using a tight-binding model for electrons, we will show that this dual electron-phonon coupling results in two types of polarons, a “super-para-electric (SPE) large polaron” with a quasi-globle parity violation, and an “off-center type self-trapped polaron” with only a local parity violation. This SPE large polaron is shown to be equal to a singly charged (e-) and conductive ferroelectric domain with a quasi-macroscopic range. Two of such large polarons are shown to aggregate and form an SPE large bipolaron, which is still conductive. Various other bipolaron clusters are also shown to be formed in this electron-phonon coupled system. These large polarons have a high mobility and an enhanced quasi-static dielectric susceptibility. Effect of adulteration is also discussed.

  11. Replacement of wheat bran with spineless cactus (Opuntia ficus indica Mill cv Gigante) and urea in the diets of Holstein x Gyr heifers.

    PubMed

    de Figueiredo Monteiro, Carolina Corrêa; Silva de Melo, Airon Aparecido; Ferreira, Marcelo Andrade; de Souza Campos, José Mauricio; Rodrigues Souza, Julyana Sena; Dos Santos Silva, Evannielly Thuanny; de Paula Xavier de Andrade, Rafael; da Silva, Emmanuelle Cordeiro

    2014-10-01

    The aim of this study was to evaluate the replacement effect of wheat bran with spineless cactus and urea in heifers. Twenty-four heifers with an average initial weight of 185?±?13 kg were used in this experiment. Four levels of spineless cactus corrected with urea and ammonium sulfate (9:1) were studied: 0, 33, 66, and 100 % replacement with wheat bran. Samples of feed, orts, and feces were analyzed to estimate the intake and digestibility of dry matter (DM) and nutrients. Indigestible neutral detergent fiber was used as an internal marker. The experiment was conducted in a completely randomized design. Dry matter, neutral detergent fiber, and total digestible nutrient intake demonstrated a quadratic effect (P?

  12. The electromagnetic ram action of the plasma focus as a paradigm for the generation of cosmic rays and the gigantic jets in active galaxies

    NASA Technical Reports Server (NTRS)

    Bostick, W. H.; Nardi, V.

    1985-01-01

    Recent measurements of the energy spectrum of the plasma-focus-generated deuteron beam yield as spectrum of the form N(E)=(approx.) E to the -2.7 for 1MeV E 13 MeV. Other measurements show that the beta 1 electron beam which is generated simultaneously with the deuteron beam is interrupted into segments of spacing 25ps and duration approximately 4ps. A stuttering-electro-magnetic-ram (ser) model of the plasma focus in proposed which is similar to Raudorf's electronic ram which produces a similar spectrum for an electron beam for 1Mev E 10MeV. It is proposed that the cosmic ray spectrum and the giganic galactic jets are both generated by ser action near the centers of active galaxies.

  13. The electromagnetic Ram action of the plasma focus as a paradigm for the generation of cosmic rays and the gigantic jets in active galaxies

    NASA Astrophysics Data System (ADS)

    Bostick, W. H.; Nardi, V.

    1985-08-01

    Recent measurements of the energy spectrum of the plasma-focus-generated deuteron beam yield as spectrum of the form N(E)=(approx.) E to the -2.7 for 1MeV E 13 MeV. Other measurements show that the beta 1 electron beam which is generated simultaneously with the deuteron beam is interrupted into segments of spacing 25ps and duration approximately 4ps. A stuttering-electro-magnetic-ram (ser) model of the plasma focus in proposed which is similar to Raudorf's electronic ram which produces a similar spectrum for an electron beam for 1Mev E 10MeV. It is proposed that the cosmic ray spectrum and the giganic galactic jets are both generated by ser action near the centers of active galaxies.

  14. McCune-Albright syndrome

    MedlinePLUS

    ... the face Gigantism Irregular, large patchy cafe-au-lait spots , especially on the back ... abnormalities Gigantism Hyperparathyroidism Hyperthyroidism Hypophosphatemia Large cafe-au-lait spots on the skin Liver disease, jaundice, fatty ...

  15. Evolutionary size changes in plants of the south-west Pacificgeb_730 819..828

    E-print Network

    their respective subgenera on the mainland. Results Although some evidence of dwarfism was observed, most insular intra-specific competition. Keywords Biogeography, dwarfism, gigantism, island, island rule, leaf

  16. Evolution on a desert island: body size divergence between the reptiles of Nevada's Anaho Island and the mainland

    E-print Network

    Feldman, Chris R

    , Austin Peay State University, Clarksville, TN, USA Keywords resource availability; competition; dwarfism on islands, with celebrated cases of both dwarfism and gigantism (Lomolino, 2005; but see Meiri, Raia

  17. Endocrine glands

    MedlinePLUS

    ... Langerhans in the pancreas Ovaries Parathyroid Pineal Pituitary Testes Thyroid ... Growth hormone deficiency Acromegaly Diabetes Gigantism Diabetes insipidus Testes and ovaries: Lack of sex development (unclear genitalia) ...

  18. Fermi discovers giant bubbles in Milky Way - Duration: 93 seconds.

    NASA Video Gallery

    Using data from NASA's Fermi Gamma-ray Space Telescope, scientists have recently discovered a gigantic, mysterious structure in our galaxy. This feature looks like a pair of bubbles extending above...

  19. SYNTHESIS Of mice and mammoths: generality and antiquity of the island rule

    E-print Network

    Sax, Dov

    to influence body size evolution in general. The more pronounced gigan- tism and dwarfism of palaeo but absent species. Keywords Body size, dwarfism, evolution, fossils, gigantism, island rule, islands

  20. Rivaling the World's Smallest Reptiles: Discovery of Miniaturized and Microendemic New Species of Leaf

    E-print Network

    limited to a very small islet, this species may represent an extreme case of island dwarfism. Citation such as gigantism and dwarfism in organisms attract considerable attention from the general public, but also allow

  1. Plant and AnimalPlant and Animal Domestication as HumanDomestication as Human--

    E-print Network

    Gepts, Paul

    , pearl millet, cowpea, melon, coffee, oil palm Maize, bean, squash, pepper, cotton, cacao Potato, cassava and Animals under Domestication (1868) #12;· Evidence for selection and inheritance? ­ Gigantism of harvested

  2. Pressure variation of Rashba spin splitting toward topological transition in the polar semiconductor BiTeI

    E-print Network

    Ideue, T.

    BiTeI is a polar semiconductor with gigantic Rashba spin-split bands in bulk. We have investigated the effect of pressure on the electronic structure of this material via magnetotransport. Periods of Shubunikov–de Haas ...

  3. the evolution of one of the most efficient biological sys-tems in the cell. They also have immense potential to be

    E-print Network

    Riggs, Austen

    , Royer et al. (2006) report the structure of the 3.6 MDa, 180-mer of Lumbricus (earthworm) hemo- globin that the extracellular hemoglobins of the earthworm, Lumbricus terrestris (LtHb), and related annelids are gigantic

  4. Plume formation in strongly temperature-dependent viscosity fluids over a very hot surface

    E-print Network

    - nificant role in global climate and mass extinctions.3,5 Although plume dynamics has been extensively to be responsible for volcanic ``hotspots'' such as Hawaii and Yellowstone and for gigantic flood basalt events

  5. Pelvic Congestion Syndrome

    PubMed Central

    Durham, Janette D.; Machan, Lindsay

    2013-01-01

    Patients with pelvic congestion syndrome present with otherwise unexplained chronic pelvic pain that has been present for greater than 6 months, and anatomic findings that include pelvic venous insufficiency and pelvic varicosities. It remains an underdiagnosed explanation for pelvic pain in young, premenopausal, usually multiparous females. Symptoms include noncyclical, positional lower back, pelvic and upper thigh pain, dyspareunia, and prolonged postcoital discomfort. Symptoms worsen throughout the day and are exacerbated by activity or prolonged standing. Examination may reveal ovarian tenderness and unusual varicosities—vulvoperineal, posterior thigh, and gluteal. Diagnosis is suspected by clinical history and imaging that demonstrates pelvic varicosities. Venography is usually necessary to confirm ovarian vein reflux, although transvaginal ultrasound may be useful in documenting this finding. Endovascular therapy has been validated by several large patient series with long-term follow-up using standardized pain assessment surveys. Embolization has been shown to be significantly more effective than surgical therapy in improving symptoms in patients who fail hormonal therapy. Although there has been variation in approaches between investigators, the goal is elimination of ovarian vein reflux with or without direct sclerosis of enlarged pelvic varicosities. Symptom reduction is seen in 70 to 90% of the treated females despite technical variation. PMID:24436564

  6. Zoropelecinus zigrasi, a pelecinid wasp in mid-Cretaceous amber from Myanmar (Hymenoptera: Pelecinidae)

    E-print Network

    Engel, Michael S.; Grimaldi, David A.; Ortega-Blanco, Jaime

    2013-09-06

    Fadden. 2004. Gigantism, dwarfism, and Cope’s rule: “Nothing in evolu- tion makes sense without a phylogeny”. Bulletin of the American Museum of Natural History 285: 219–237. Haliday, A.H. 1839. Hymenopterorum synopsis ad methodum clm. Fallenii utplurimum...Fadden. 2004. Gigantism, dwarfism, and Cope’s rule: “Nothing in evolu- tion makes sense without a phylogeny”. Bulletin of the American Museum of Natural History 285: 219–237. Haliday, A.H. 1839. Hymenopterorum synopsis ad methodum clm. Fallenii utplurimum...

  7. AIP mutation in pituitary adenomas in the 18th century and today.

    PubMed

    Chahal, Harvinder S; Stals, Karen; Unterländer, Martina; Balding, David J; Thomas, Mark G; Kumar, Ajith V; Besser, G Michael; Atkinson, A Brew; Morrison, Patrick J; Howlett, Trevor A; Levy, Miles J; Orme, Steve M; Akker, Scott A; Abel, Richard L; Grossman, Ashley B; Burger, Joachim; Ellard, Sian; Korbonits, Márta

    2011-01-01

    Gigantism results when a growth hormone-secreting pituitary adenoma is present before epiphyseal fusion. In 1909, when Harvey Cushing examined the skeleton of an Irish patient who lived from 1761 to 1783, he noted an enlarged pituitary fossa. We extracted DNA from the patient's teeth and identified a germline mutation in the aryl hydrocarbon-interacting protein gene (AIP). Four contemporary Northern Irish families who presented with gigantism, acromegaly, or prolactinoma have the same mutation and haplotype associated with the mutated gene. Using coalescent theory, we infer that these persons share a common ancestor who lived about 57 to 66 generations earlier. PMID:21208107

  8. Mol. Biol. Evol. 18(2):246253. 2001 2001 by the Society for Molecular Biology and Evolution. ISSN: 0737-4038

    E-print Network

    Hartl, Daniel L.

    . ISSN: 0737-4038 Genomic Gigantism: DNA Loss Is Slow in Mountain Grasshoppers Douda Bensasson,* Dmitri A pedestris, the brown mountain grasshopper, has a genome over 100 times as large as that of Drosophila and 10 lower in the grasshoppers studied than in Drosophila or Laupala. This suggests that the inverse

  9. Developments in South American Squid Fisheries

    E-print Network

    Developments in South American Squid Fisheries Marcelo Juanico is with the Museo Nacional deI., 1975). Up to now squids have been only a minor and scarce resource in the Chilean fisheries, recorded gigante," Humboldt squid) with a man- tle length of up to I m and a weight of 35 kg. It is fished mainly

  10. Not Your Parents' Marching Bands: The History of HONK!, Pedagogy and Music Education

    ERIC Educational Resources Information Center

    Garofalo, Reebee

    2011-01-01

    The HONK! Festival of Activist Street Bands (honkfest.org) is an independent, grassroots, non-commercial weekend festival held each autumn in Somerville, Massachusetts. It is a moving spectacle of colourful marching bands, gigantic puppets, creative bikers, jugglers, hoopers, flag twirlers and stilt walkers, interspersed with unions, activist…

  11. The atoms may be charged or neutral (how?) mass range: 1.67 10-27

    E-print Network

    and fission "The sun is a mass of incandescent gas A gigantic nuclear furnace Where hydrogen is built ­ Why does the Sun shine (pictures not to scale) http://www.johnharveyphoto.com/RoadTrip/NuclearReactor.html Your local (still active) G star SUN; Orion Arm, MW X ray picture Your local (retired) nuclear plant

  12. The island rule and the evolution of body size in the deep sea

    E-print Network

    Boyer, Alison G.

    , 2002; Palkovacs, 2003). Typically small-bodied vertebrates exhibit gigantism on islands, while dwarfism to survive and reproduce. The resulting tendency toward insular dwarfism should be most prevalent in species-bodied species to dwarfism in large-bodied species ­ in the deep sea, a non-insular but potentially analogous

  13. COMMUNICATION 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim (1 of 8) 1500076wileyonlinelibrary.com

    E-print Network

    Wang, Wei Hua

    in which magnetostructural coupling can occur will be expanded largely. As a rising family of FMMT materials, the hexagonal MMX (M, M = transition metals, X = carbon or boron group ele- ments) compounds have by small thermal hysteresis, high temperature-sensitivity, high Curie-temperatures, gigantic anisotropic

  14. Riding the Dinosaur Wave.

    ERIC Educational Resources Information Center

    Girod, Mark

    1998-01-01

    As his geology students' specialized knowledge of the Mesozoic era increased, a high school teacher realized he needed a way to showcase their work. The Mesozoic Resource Center's biggest hit was a walk-through diorama showing how life might have been during each of three Mesozoic periods. Highlights included two gigantic student-built dinosaur…

  15. Energetics of protein charge transfer and photosynthesis

    E-print Network

    Matyushov, Dmitry

    from redox chemistry: = 1 eV Do molecules present a dead case for solar energy conversion? Why does+ Electrostatics facts: Dipole moment ~ 2400 D Observables: #12; Gigantic reorganization energy of electron electron hops! #12; Energy loss to the phonon bath Moving electron with zero activation barrier requires

  16. Rock "n" Roll Presidents on Mount Rushmore. Second Grade Activity. Schools of California Online Resources for Education (SCORE): Connecting California's Classrooms to the World.

    ERIC Educational Resources Information Center

    Sawyer, Debbie

    A historian, Doane Robinson, and a sculptor, Gutzon Borglum, worked together to build a gigantic monument in South Dakota that honored four of the greatest U.S. presidents: George Washington, Abraham Lincoln, Theodore Roosevelt, and Thomas Jefferson. Robinson and Borglum wanted the monument to represent U.S. ideals. To celebrate the anniversary of…

  17. Variations on a Theme: Fourth Annual Review, 1969-70.

    ERIC Educational Resources Information Center

    Committee of Presidents of Universities of Ontario, Toronto.

    Over the past several years the universities of Ontario have made a gigantic effort under the direction of the Committee of Presidents of Universities of Ontario to provide quality higher education for all qualified students. Inter institutional cooperation and coordination has been a must in this effort, and maximum utilization of available…

  18. Oxygen from the lunar soil by molten silicate electrolysis

    NASA Technical Reports Server (NTRS)

    Colson, Russell O.; Haskin, Larry A.

    1992-01-01

    Accepting that oxygen, rather than gigantic gems or gold, is likely to make the Moon's Klondike, the extraction of oxygen from the lunar soil by molten silicate electrolysis has chosen to be investigated. Process theory and proposed lunar factory are addressed.

  19. Superiority, Competition, and Opportunism in the Evolutionary

    E-print Network

    Benton, Michael

    of character evolution from body plan variety. The results strongly suggest that historical contingency, rather dinosaurian body plans (large terrestrial predators; small swift predators; mid- to large-bodied low, and the range of body sizes ex- panded to include truly gigantic forms (1, 2). Through this expansion

  20. Biology 495: Monster Biology Syllabus, Spring 2002

    E-print Network

    Warrick, Douglas R.

    Mothra, 1962 ) Feb. 26, 28 Aquatic animals: Diving Physiology, Reynolds number, flow, and locomotion. (It 1998) Mar. 5, 7 Fossorial critters: Biomechanics, scaling, and physiology (Tremors ; The Mole People The physiology of gigantism: scaling of the cardiovascular and nervous systems (King Kong, 1932 ) Mar. 26, 28

  1. Coral Reefs: A Gallery Program, Grades 7-12.

    ERIC Educational Resources Information Center

    National Aquarium in Baltimore, MD. Dept. of Education.

    Gallery classes at the National Aquarium in Baltimore give the opportunity to study specific aquarium exhibits which demonstrate entire natural habitats. The coral reef gallery class features the gigantic western Atlantic coral reef (325,000 gallons) with over 1,000 fish. The exhibit simulates a typical Caribbean coral reef and nearby sandy…

  2. Molecular Clouds, Star Formation and Galactic Structure.

    ERIC Educational Resources Information Center

    Scoville, Nick; Young, Judith S.

    1984-01-01

    Radio observations show that the gigantic clouds of molecules where stars are born are distributed in various ways in spiral galaxies, perhaps accounting for the variation in their optical appearance. Research studies and findings in this area are reported and discussed. (JN)

  3. Hermann Friedberg's case report: an early description of CLOVES syndrome.

    PubMed

    Alomari, A I; Thiex, R; Mulliken, J B

    2010-10-01

    CLOVES syndrome is a recently described overgrowth disorder with complex vascular anomalies. Careful analysis of the case report by the German physician Hermann Friedberg "gigantism of the right lower limb" published in 1867 revealed that the report probably represents one of the first written accounts of CLOVES syndrome. PMID:21050185

  4. [Acromegaly--from myths to facts].

    PubMed

    Ka?uzny, Marcin; Bolanowski, Marek

    2008-01-01

    The authors present numerous historical descriptions of persons who might suffered from gigantism or acromegaly. The oldest medical data of patients, initial attempts of causal neurosurgical treatment, history of growth hormone, insulin-like growth factor-1, growth hormone releasing hormone and somatostatin discovery is reported. The highest contemporary living persons are also listed. PMID:18615400

  5. PUBLISHED ONLINE: 23 AUGUST 2009 | DOI: 10.1038/NGEO607 Quantification of the troposphere-to-ionosphere

    E-print Network

    Cummer, Steven A.

    suggested4 . Radar reflectivity measured two minutes before the event (Fig. 1b) shows the captured sequence. b, Radar reflectivity measured two minutes before the gigantic jet occurred in strong cloud-to-ground lightning strokes. At a field site near Duke University, we routinely monitor

  6. 12 DECEMBER 2014 VOL 346 ISSUE 6215 1341SCIENCE sciencemag.org BACKGROUND: The origin of birds is one

    E-print Network

    Chuong, Cheng-Ming

    early in dinosaur evolution, with some approaching modern conditions well before the origin of birds small-sized birds are nested within a theropod dinosaur group that in- cludes the gigantic Tyrannosaurus history of selected bird features inferred from multidisciplinary data. Recent studies demonstrate

  7. National High Magnetic Field Laboratory Pulsed Field Facility Los Alamos National Laboratory is home to the National High

    E-print Network

    magnetic fields and then controllably shut off before the gigantic electromagnetic forces and temperatures equivalent to about 85 sticks of dynamite). As well, capacitor banks power a wide range of magnets to organic-based magnets, arrive at the NHMFL-PFF to unlock the fundamental physics behind the material

  8. Gender, Education and Child Labour: A Sociological Perspective

    ERIC Educational Resources Information Center

    Bhat, Bilal Ahmad

    2010-01-01

    In all societies, boys and girls are assigned different societal roles and experience different perspectives of life as a result of their being male or female. Such differences have a gigantic impact on their lives. The importance of gender perspective is very important in understanding the convolution of child labour. Gender, as opposed to sex,…

  9. Exponential growth, energetic Hubbert cycles, and the advancement of technology

    E-print Network

    Patzek, Tadeusz W.

    supply of the Unites States. 1 Introduction Just like bacteria, fungi, and higher animals, humans continued until whales neared extinction. Fast forward 150 years. By 2008, the gigantic agrofuel plantations Fair on April 20, 1861, were thankful to Seneca Oil for saving them from extinction. 1.2 Resources

  10. Shake It up

    ERIC Educational Resources Information Center

    Gilstrap, Tatiana; Sheldon, Peter; Schimmoeller, Peggy

    2010-01-01

    If scientists know where earthquakes are most likely to occur, then architects and engineers can design safer buildings for such areas and potentially prevent some of the devastating aftereffects. Engineers have met this challenge through the design and use of gigantic shake tables to evaluate the stability of various structures. In this 45-minute…

  11. by Kamini Singha, Geological and Environmental Sciences Approximately

    E-print Network

    Singha, Kamini

    on using methods that allow us to "see" into the Earth, similar to a medical CAT scan, to help determine to collecting gigantic CAT scans. CAT scans produce high energy electromagnetic waves, similar to visible light, but with higher energy that allows them to pass through our bodies. The resultant scan is basically a record

  12. Gadsby Gadsby: a story of over 50,000 words without using the letter ...

    E-print Network

    Go to Indo-China and visit its gigantic Ankhor Vat; call at Damascus, Baghdad and ...... such prolific flows of high-sounding words as his antagonists had in stock. ..... girls brought in willow twigs, ivy roots, bulbs of canna, dahlia, calladium, tulip, ...

  13. Abrupt changes in defence and trophic morphology of the giant threespine stickleback (Gasterosteus sp.)

    E-print Network

    Reimchen, Thomas E.

    -plated adult threespine stickleback (Gasterosteus aculeatus) exhibiting gigantism in body size and robustAbrupt changes in defence and trophic morphology of the giant threespine stickleback (Gasterosteus spines were transferred in 1993 from a large dystrophic lake (Mayer Lake, Haida Gwaii, British Columbia

  14. Quicksilver/OCaml: A Poor Man's TypeSafe and AbstractionSecure Communication Library

    E-print Network

    Sumii, Eijiro

    and safety''). 2 See, for instance, the gigantic thread in the TYPES mailing list, start­ ing at http://www.seas.upenn.edu/~sweirich/types/archive network environment without losing type safety or abstraction. It is entirely implemented at user level, i safety, but also security against malicious attackers is required. 1. Introduction Safety and security

  15. Quicksilver/OCaml: A Poor Man's Type-Safe and Abstraction-Secure Communication Library

    E-print Network

    Sumii, Eijiro

    and safety"). 2 See, for instance, the gigantic thread in the TYPES mailing list, start- ing at http://www.seas.upenn.edu/~sweirich/types/archive network environment without losing type safety or abstraction. It is entirely implemented at user level, i safety, but also security against malicious attackers is required. 1. Introduction Safety and security

  16. The Story of Semco: The Company that Humanized Work

    ERIC Educational Resources Information Center

    Vanderburg, David

    2004-01-01

    This article examines and analyzes Semco, a company that changed the way it viewed and treated its workers for the better. It is the contention of Semco's CEO, that at most large corporations "everyone is part of a gigantic, impersonal machine, and it is impossible to feel motivated when you feel you are just another cog. Human nature demands…

  17. Vida Nocturna | Vias Chilenas | Hoteles | Rent a Car | Turismo Aventura | A Domicilio | Inmobiliarias | Restaurantes Cosas de la Gentica

    E-print Network

    Lummaa, Virpi

    prolongada a las hormonas del sexo opuesto. Para investigar los efectos de la testosterona en la fertilidad que Reconoce su Habla Gusano Se Oculta en Video de YouTube En Cerro Paranal Descubren Estrella Gigante Chile RESERVA TU HOTEL videos de Chile vinos de Chile SERVICIOS a domicilio aerolíneas agencias de

  18. The Experience of External Studies. Occasional Papers No. 4.

    ERIC Educational Resources Information Center

    Riverina Coll. of Advanced Education, Wagga Wagga, New South Wales (Australia).

    This document brings together four invited papers by external students who have graduated from Riverina College: (1) "The External Student: One Profile" (Christine Del Gigante); (2) "Managing Life as a External Student" (Robert Landow); (3) "The Computerised Student" (John Chant); and (4) "The Right to Study" (Coral Davidson). Topics covered…

  19. snRNAs as the catalysts of pre-mRNA splicing Saba Valadkhan

    E-print Network

    Valadkhan, Saba

    snRNAs as the catalysts of pre-mRNA splicing Saba Valadkhan The spliceosome, the gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and five RNA U1 at the 50 splice site, and forms a base-pairing interaction with U2 snRNA that juxtaposes the 50

  20. J. Zoo/., Lond (2000) 251, 369-375 2000 The Zoological Society of London Printed in the United Kingdom The relationship of neonate mass and incubation temperature

    E-print Network

    Gillooly, Jamie

    2000-01-01

    defined such as the 'mouse to elephant curve' for metabolic rate. In endotherms, embryonic develop ment of animals, ectothermic and endothermic, invertebrate and vertebrate, microscopic and gigantic. We begin) and endotherms (birds and mammals) in terms of degree-days. The similar nature of these relationships allows us

  1. This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon.

    E-print Network

    Lazzaro, Brian

    host sexes, the parasite causes a similar reduction in longevity and leads to some level of castration. However, only in females does parasite-induced castration result in the gigantism that increases represent different environments and reveal one parasite-induced symptom (host castration), which leads

  2. Mathematics in Use: Suspension Bridges.

    ERIC Educational Resources Information Center

    Ginther, John L.

    1992-01-01

    Reviews the mathematics utilized in the design and construction of suspension bridges, in general, then illustrates these mathematical concepts by examining data associated with the Mackinac Bridge, which connects the two peninsulas of Michigan. Emphasizes the strong interest factor these gigantic structures have for students by attaching a sense…

  3. Call for Applications for a Tenure-Track Position at Chiba University 2015 We are inviting applications for a tenure-track position (at the rank of assistant professor) for a

    E-print Network

    Sakurai, Takafumi

    to become a future leader in earth science areas. Both research and educational abilities (planning skills tenure-track faculty will become a tenured position at the Department of Earth Sciences, Chiba University. 2. Research and Education area: Earth sciences related to gigantic earthquakes along and around

  4. Fossils and Dinosaurs--A Fully Integrated Instructional Unit.

    ERIC Educational Resources Information Center

    Kuehl, Matt; And Others

    This lesson plan for the second and third grades uses information on dinosaurs, their adaptations and survival, to provide science education for limited-English-proficient (LEP) students in San Diego, California. The primary text is "Los Dinosaurios Gigantes," a core literature book used in the school district. Lessons are based on the whole…

  5. Kuba, Kids, and an Airport: How One Community Celebrates Art and Imagination.

    ERIC Educational Resources Information Center

    Eller, Lennee; Grigsby, Eugene, Jr.

    2003-01-01

    Describes "The Kuba Project: An Exhibit of Gigantic Proportions" in which high school students learned about the Kuba people of the Congo and created monumental ceramic works of art. Explains that the student artwork was exhibited at the Phoenix Sky Harbor International Airport in Phoenix (Arizona) as part of the Sky Harbor Art Program. (CMK)

  6. A lopsided planet Photolibrary

    E-print Network

    Nimmo, Francis

    by an asteroid. Nothing surprising in that: one look at the Red Planet's crater- pocked surface is enough planet. the IDea that the northern lowlands might be a humongous impact crater isn't new. American right. Craters are usually circular. The basin isn't. Partly that's because a group of gigantic

  7. Macrodystrophia lipomatosa of the foot: A case report

    PubMed Central

    ÇELEBI, FILIZ; KARAGULLE, KAGAN; ONER, ALI YUSUF

    2015-01-01

    Macrodystrophia lipomatosa is a sporadic, nonhereditary developmental anomaly and a rare form of congenital localized gigantism. It is characterized by the proliferation of all the mesenchymal elements of a digit or digits, and a disproportionate increase of fibroadipose tissue involving the nerve sheath, muscle, periosteum and bone marrow. In the present study, a 9-month-old boy was referred to Gazi University Hospital (Ankara, Turkey) with congenital unilateral enlargement of the right forefoot, particularly involving the second and third toes. X-ray and magnetic resonance imaging (MRI) scans were performed in order to assess the skeletal structures. The present study described the characteristic imaging features, with an emphasis on the MRI findings, of this rare congenital form of gigantism. PMID:26622602

  8. A giant phyllodes tumor causing ulceration and severe breast disfigurement: case report and review of giant phyllodes

    PubMed Central

    Sbeih, Mohammed A.; Engdahl, Ryan; Landa, Marina; Ojutiku, Oreoluwa; Morrison, Norman; Depaz, Hector

    2015-01-01

    Phyllodes tumors are rare fibroepithelial tumors that account for <1% of the breast tumors in women. These tumors are often benign unilateral lesions of the female breast (70%). Less common are malignant phyllodes, which have the potential for hematogenous spread. Phyllodes tumors can be seen in all age groups, and the median age of presentation is 45 years. Surgery is the main form of treatment. Wide excisions with margins of 1cm are suggested. While smaller and moderate size phyllodes may typically be seen, gigantic ones are very rare. These may be seen in neglected tumors. By definition, a giant phyllodes tumor is one larger than 10 cm in diameter. We report a gigantic phyllodes tumor that grew over 7 years period causing significant ulceration and disfigurement and review features of these tumors and management. PMID:26703928

  9. High-altitude electrical discharges associated with thunderstorms and lightning

    NASA Astrophysics Data System (ADS)

    Liu, Ningyu; McHarg, Matthew G.; Stenbaek-Nielsen, Hans C.

    2015-12-01

    The purpose of this paper is to introduce electrical discharge phenomena known as transient luminous events above thunderstorms to the lightning protection community. Transient luminous events include the upward electrical discharges from thunderstorms known as starters, jets, and gigantic jets, and electrical discharges initiated in the lower ionosphere such as sprites, halos, and elves. We give an overview of these phenomena with a focus on starters, jets, gigantic jets, and sprites, because similar to ordinary lightning, streamers and leaders are basic components of these four types of transient luminous events. We present a few recent observations to illustrate their main properties and briefly review the theories. The research in transient luminous events has not only advanced our understanding of the effects of thunderstorms and lightning in the middle and upper atmosphere, but also improved our knowledge of basic electrical discharge processes critical for sparks and lightning.

  10. Latent outflow activity for western Tharsis, Mars: Significant flood record exposed

    USGS Publications Warehouse

    Dohm, J.M.; Anderson, R.C.; Baker, V.R.; Ferris, J.C.; Rudd, L.P.; Hare, T.M.; Rice, J.W., Jr.; Casavant, R.R.; Strom, R.G.; Zimbelman, J.R.; Scott, D.H.

    2001-01-01

    Observations permitted by the newly acquired Mars Observer Laser Altimeter data have revealed a system of gigantic valleys northwest of the huge Martian shield volcano, Arsia Mons, in the western hemisphere of Mars (northwestern slope valleys (NSVs)). These features, which generally correspond spatially to gravity lows, are obscured by veneers of materials including volcanic lava flows, air fall deposits, and eolian materials. Geologic investigations of the Tharsis region suggest that the system of gigantic valleys predates the construction of Arsia Mons and its extensive associated lava flows of mainly late Hesperian and Amazonian age and coincides stratigraphically with the early development of the outflow channels that debouch into Chryse Planitia. Similar to the previously identified outflow channels, which issued tremendous volumes of water into topographic lows such as Chryse Planitia, the NSVs potentially represent flooding of immense magnitude and, as such, a source of water for a northern plains ocean.

  11. Proteus syndrome: A rare case report

    PubMed Central

    Talari, Keerthi; Subbanna, Praveen Kumar Arinaganhalli; Amalnath, Deepak; Suri, Subrahmanyam Dharanitragada Krishna

    2012-01-01

    Proteus syndrome (PS) is a rare hamartomatous disorder characterized by various cutaneous and subcutaneous lesions, including vascular malformations, lipomas, hyperpigmentation, and several types of nevi. Partial gigantism with limb or digital overgrowth is pathognomonic of PS. We report a rare case of PS in a 50-year-old man who presented with inferior wall myocardial infarction and was incidentally detected to have hypertrophy of index and middle fingers of both the hands. PMID:23716948

  12. Four new bat species (Rhinolophus hildebrandtii complex) reflect Plio-Pleistocene divergence of dwarfs and giants across an Afromontane archipelago.

    PubMed

    Taylor, Peter J; Stoffberg, Samantha; Monadjem, Ara; Schoeman, Martinus Corrie; Bayliss, Julian; Cotterill, Fenton P D

    2012-01-01

    Gigantism and dwarfism evolve in vertebrates restricted to islands. We describe four new species in the Rhinolophus hildebrandtii species-complex of horseshoe bats, whose evolution has entailed adaptive shifts in body size. We postulate that vicissitudes of palaeoenvironments resulted in gigantism and dwarfism in habitat islands fragmented across eastern and southern Africa. Mitochondrial and nuclear DNA sequences recovered two clades of R. hildebrandtii senso lato which are paraphyletic with respect to a third lineage (R. eloquens). Lineages differ by 7.7 to 9.0% in cytochrome b sequences. Clade 1 includes R. hildebrandtii sensu stricto from the east African highlands and three additional vicariants that speciated across an Afromontane archipelago through the Plio-Pleistocene, extending from the Kenyan Highlands through the Eastern Arc, northern Mozambique and the Zambezi Escarpment to the eastern Great Escarpment of South Africa. Clade 2 comprises one species confined to lowland savanna habitats (Mozambique and Zimbabwe). A third clade comprises R. eloquens from East Africa. Speciation within Clade 1 is associated with fixed differences in echolocation call frequency, and cranial shape and size in populations isolated since the late Pliocene (ca 3.74 Mya). Relative to the intermediate-sized savanna population (Clade 2), these island-populations within Clade 1 are characterised by either gigantism (South African eastern Great Escarpment and Mts Mabu and Inago in Mozambique) or dwarfism (Lutope-Ngolangola Gorge, Zimbabwe and Soutpansberg Mountains, South Africa). Sympatry between divergent clades (Clade 1 and Clade 2) at Lutope-Ngolangola Gorge (NW Zimbabwe) is attributed to recent range expansions. We propose an "Allometric Speciation Hypothesis", which attributes the evolution of this species complex of bats to divergence in constant frequency (CF) sonar calls. The origin of species-specific peak frequencies (overall range = 32 to 46 kHz) represents the allometric effect of adaptive divergence in skull size, represented in the evolution of gigantism and dwarfism in habitat islands. PMID:22984399

  13. Four New Bat Species (Rhinolophus hildebrandtii Complex) Reflect Plio-Pleistocene Divergence of Dwarfs and Giants across an Afromontane Archipelago

    PubMed Central

    Taylor, Peter J.; Stoffberg, Samantha; Monadjem, Ara; Schoeman, Martinus Corrie; Bayliss, Julian; Cotterill, Fenton P. D.

    2012-01-01

    Gigantism and dwarfism evolve in vertebrates restricted to islands. We describe four new species in the Rhinolophus hildebrandtii species-complex of horseshoe bats, whose evolution has entailed adaptive shifts in body size. We postulate that vicissitudes of palaeoenvironments resulted in gigantism and dwarfism in habitat islands fragmented across eastern and southern Africa. Mitochondrial and nuclear DNA sequences recovered two clades of R. hildebrandtii senso lato which are paraphyletic with respect to a third lineage (R. eloquens). Lineages differ by 7.7 to 9.0% in cytochrome b sequences. Clade 1 includes R. hildebrandtii sensu stricto from the east African highlands and three additional vicariants that speciated across an Afromontane archipelago through the Plio-Pleistocene, extending from the Kenyan Highlands through the Eastern Arc, northern Mozambique and the Zambezi Escarpment to the eastern Great Escarpment of South Africa. Clade 2 comprises one species confined to lowland savanna habitats (Mozambique and Zimbabwe). A third clade comprises R. eloquens from East Africa. Speciation within Clade 1 is associated with fixed differences in echolocation call frequency, and cranial shape and size in populations isolated since the late Pliocene (ca 3.74 Mya). Relative to the intermediate-sized savanna population (Clade 2), these island-populations within Clade 1 are characterised by either gigantism (South African eastern Great Escarpment and Mts Mabu and Inago in Mozambique) or dwarfism (Lutope-Ngolangola Gorge, Zimbabwe and Soutpansberg Mountains, South Africa). Sympatry between divergent clades (Clade 1 and Clade 2) at Lutope-Ngolangola Gorge (NW Zimbabwe) is attributed to recent range expansions. We propose an “Allometric Speciation Hypothesis”, which attributes the evolution of this species complex of bats to divergence in constant frequency (CF) sonar calls. The origin of species-specific peak frequencies (overall range?=?32 to 46 kHz) represents the allometric effect of adaptive divergence in skull size, represented in the evolution of gigantism and dwarfism in habitat islands. PMID:22984399

  14. Tidal Effects of Passing Planets and Mass Extinctions

    E-print Network

    Daniele Fargion; Arnon Dar

    1998-02-20

    Recent observations suggest that many planetary-mass objects may be present in the outer solar system between the Kuiper belt and the Oort cloud. Gravitational perturbations may occasionally bring them into the inner solar system. Their passage near Earth could have generated gigantic tidal waves, large volcanic eruptions, sea regressions, large meteoritic impacts and drastic changes in global climate. They could have caused the major biological mass extinctions in the past 600 My as documented in the geological records.

  15. Structural advances on titin: towards an atomic understanding of multi-domain functions in myofilament mechanics and scaffolding.

    PubMed

    Zacharchenko, Thomas; von Castelmur, Eleonore; Rigden, Daniel J; Mayans, Olga

    2015-10-01

    Titin is a gigantic filamentous protein of the muscle sarcomere that plays roles in myofibril mechanics and homoeostasis. 3D-structures of multi-domain fragments of titin are now available that start revealing the molecular mechanisms governing its mechanical and scaffolding functions. This knowledge is now being translated into the fabrication of self-assembling biopolymers. Here we review the structural advances on titin, the novel concepts derived from these and the emerging translational avenues. PMID:26517893

  16. Low H/L of initial and secondary landslides on Mars Valles Marineris floor

    NASA Astrophysics Data System (ADS)

    Sagi, H.; Fukuoka, H.

    2012-12-01

    The Mars Global Surveyer (MGS) has investigated the almost whole Martian topography with high resolution and its products are reflected in the Google Earth's martian option. This digital service provide huge opportunities to public to view the preserved landslide topography as well as to measure the parameters for landslide mobility such as average coefficient of friction (H/L), and apparent friction angle. Among those views, the Valles Marineris is the most landslide prone area and a lot of long runout gigantic landslides can be extracted along the tectonic cliff. Authors encouraged undergraduate students to measure this parameter as an exercise of introductory course of planetary science, especially of the gigantic initial landslides to compare with those of secondary landslides which looks like induced by subsequent triggers such as earthquake or metor impact. Preliminary results show that (1) The H/L values of the gigantic initial landslides are dependent on landslide volume as reported by previous studies; (2) secondary landslides of much less volumes generally have wide and thin spread features but much smaller friction like debris flows. Those characters imply that those landslides might have been induced in the landslide deposits of higher moisture content and/or runout on valley floor of highly saturated or shallow ground water table.

  17. Discos de acreción circumplanares: Modelo de Co-acreción

    NASA Astrophysics Data System (ADS)

    Parisi, M. G.; de Elía, G.

    Los discos de acreción circumplanetarios precursores de los satélites regulares de los planetas gigantes, se pueden formar por cuatro mecanismos (Pollack y otros, 1991, In Uranus, Bergtralh, Miner y Mattews, Eds., p. 469, Univ. de Arizona Press, Tucson). En este trabajo estudiamos uno de tales mecanismos: el Modelo de Co-acreción. En dicho modelo, el disco circumplanetario se forma a partir de las colisiones mutuas entre planetesimales dentro de la esfera de Hill del planeta durante el proceso de formación planetaria. Realizamos un modelo semi-analítico para calcular la masa del disco y compararla con la masa requerida para formar los satélites regulares de los planetas gigantes. Hemos obtenido una cota superior para la masa del disco que resulta inferior a la masa de los satélites más grandes de los planetas gigantes. En principio, estos resultados permitirían descartar el modelo de co-acreción como uno de los procesos que podrían dar lugar a la formación de los satélites regulares. Estos resultados permiten obtener restricciones en el escenario de formación planetaria y en los mecanismos de formación de sistemas de satélites.

  18. The Giant Jet

    NASA Astrophysics Data System (ADS)

    Neubert, T.; Chanrion, O.; Arnone, E.; Zanotti, F.; Cummer, S.; Li, J.; Füllekrug, M.; van der Velde, O.

    2012-04-01

    Thunderstorm clouds may discharge directly to the ionosphere in spectacular luminous jets - the longest electric discharges on our planet. The electric properties of jets, such as their polarity, conductivity, and currents, have been predicted by models, but are poorly characterized by measurements. Here we present an analysis of the first gigantic jet that with certainty has a positive polarity. The jet region in the mesosphere was illuminated by an unusual sprite discharge generated by a positive cloud-to-ground lightning flash shortly after the onset of the jet. The sprite appeared with elements in a ring at ~40 km distance around the jet, the elements pointing curving away from the jet. This suggests that the field close the jet partially cancels the field driving the sprite. From a simple model of the event we conclude that a substantial portion of the positive cloud potential must be carried to ~50 km altitude, which is also consistent with the observed channel expansion and the electromagnetic radiation associated with the jet. It is further shown that blue jets are likely to substantially modify the free electron content in the lower ionosphere because of increased electron attachment driven by the jet electric field. The model further makes clear the relationship between jets, gigantic jets, and sprites. This is the first time that sprites are used for sounding the properties of the mesosphere. The observations presented here will allow evaluation of theories for jet and gigantic jet generation and of their influence on the atmosphere-ionosphere system.

  19. A unified model with a generalized gauge symmetry and its cosmological implications

    NASA Astrophysics Data System (ADS)

    Jong-Ping, Hsu; Kazuo, O. Cottrell

    2015-10-01

    A unified model is based on a generalized gauge symmetry with groups [SU3c]color×(SU2×U1)× [U1b×U1l]. It implies that all interactions should preserve conservation laws of baryon number, lepton number, and electric charge, etc. The baryonic U1b, leptonic U1l and color SU3c gauge transformations are generalized to involve nonintegrable phase factors. One has gauge invariant fourth-order equations for massless gauge fields, which leads to linear potentials in the [U1b×U1l] and color [SU3c] sectors. We discuss possible cosmological implications of the new baryonic gauge field. It can produce a very small constant repulsive force between two baryon galaxies (or between two anti-baryon galaxies), where the baryon force can overcome the gravitational force at very large distances and leads to an accelerated cosmic expansion. Based on conservation laws in the unified model, we discuss a simple rotating dumbbell universe with equal amounts of matter and anti-matter, which may be pictured as two gigantic rotating clusters of galaxies. Within the gigantic baryonic cluster, a galaxy will have an approximately linearly accelerated expansion due to the effective force of constant density of all baryonic matter. The same expansion happens in the gigantic anti-baryonic cluster. Physical implications of the generalized gauge symmetry on charmonium confining potentials due to new SU3c field equations, frequency shift of distant supernovae Ia and their experimental tests are discussed.

  20. X-linked Acrogigantism (X-LAG) Syndrome: Clinical Profile and Therapeutic Responses

    PubMed Central

    Beckers, Albert; Lodish, Maya Beth; Trivellin, Giampaolo; Rostomyan, Liliya; Lee, Misu; Faucz, Fabio R; Yuan, Bo; Choong, Catherine S; Caberg, Jean-Hubert; Verrua, Elisa; Naves, Luciana Ansaneli; Cheetham, Tim D; Young, Jacques; Lysy, Philippe A; Petrossians, Patrick; Cotterill, Andrew; Shah, Nalini Samir; Metzger, Daniel; Castermans, Emilie; Ambrosio, Maria Rosaria; Villa, Chiara; Strebkova, Natalia; Mazerkina, Nadia; Gaillard, Stéphan; Barra, Gustavo Barcelos; Casulari, Luis Augusto; Neggers, Sebastian J.; Salvatori, Roberto; Jaffrain-Rea, Marie-Lise; Zacharin, Margaret; Santamaria, Beatriz Lecumberri; Zacharieva, Sabina; Lim, Ee Mun; Mantovani, Giovanna; Zatelli, Maria Chaira; Collins, Michael T; Bonneville, Jean-François; Quezado, Martha; Chittiboina, Prashant; Oldfield, Edward H.; Bours, Vincent; Liu, Pengfei; De Herder, Wouter; Pellegata, Natalia; Lupski, James R.; Daly, Adrian F.; Stratakis, Constantine A.

    2015-01-01

    X-linked acro-gigantism (X-LAG) is a new syndrome of pituitary gigantism, caused by microduplications on chromosome Xq26.3, encompassing the gene GPR101, which is highly upregulated in pituitary tumors. We conducted this study to explore the clinical, radiological and hormonal phenotype and responses to therapy in patients with X-LAG syndrome. The study included 18 patients (13 sporadic) with X-LAG and a microduplication in chromosome Xq26.3. All sporadic cases had unique duplications and the inheritance pattern in 2 families was dominant with all Xq26.3 duplication carriers being affected. Patients began to grow rapidly as early as 2–3 months of age (median 12 months). At diagnosis (median delay 27 months), patients had a median height and weight SDS score of >+3.9 SDS. Apart from the increased overall body size, the children had acromegalic symptoms including acral enlargement and facial coarsening. More than a third of cases had increased appetite. Patients had marked hypersecretion of GH/IGF-1 and prolactin, usually due to a pituitary macroadenoma or hyperplasia. Primary neurosurgical control was achieved with extensive anterior pituitary resection but postoperative hypopituitarism was frequent. Control with somatostatin analogs was not readily achieved despite moderate to high somatostatin receptor subtype-2 expression in tumor tissue. Postoperative adjuvant pegvisomant achieved control of IGF-1 all 5 cases in which it was employed. X-LAG is a new infant-onset gigantism syndrome that has a severe clinical phenotype leading to challenging disease management. PMID:25712922

  1. A minimal form of Proteus syndrome presenting with macrodactyly and hand hyperplasia.

    PubMed

    Morelli, Federica; Feliciani, Claudio; Toto, Paola; De Benedetto, Anna; Tulli, Antonello

    2003-01-01

    Proteus syndrome is a rare congenital disorder characterized by progressive course and great variability of clinical presentation with partial gigantism of extremities, hemihyperplasia with macrocephaly, epidermal nevus, mesodermal hamartomas and the presence of peculiar cerebriform masses on the palms/soles. Many atypical cases have been reported and this is probably due to the mosaicism of the genetic disorder displaying different clinical features. We describe a patient with an extremely mild form of Proteus syndrome presenting macrodactyly and hyperplasia of one hand which was misdiagnosed until the age of 33 years. PMID:12695139

  2. Molarization of Mandibular Second Premolar

    PubMed Central

    Singh Khinda, Vineet Inder; Kallar, Shiminder; Singh Brar, Gurlal

    2014-01-01

    ABSTRACT Macrodontia (megadontia, megalodontia, mac rodontism) is a rare shape anomaly that has been used to describe dental gigantism. Mandibular second premolars show an elevated variability of crown morphology, as are its eruptive potential and final position in the dental arch. To date, only eight cases of isolated macrodontia of second premolars have been reported in the literature. This case report presents clinical and radiographic findings of unusual and rare case of isolated unilateral molarization of left mandibular second premolar. How to cite this article: Mangla N, Khinda VIS, Kallar S, Brar GS. Molarization of Mandibular Second Premolar. Int J Clin Pediatr Dent 2014;7(2):137-139. PMID:25356014

  3. Slimeware: engineering devices with slime mold.

    PubMed

    Adamatzky, Andrew

    2013-01-01

    The plasmodium of the acellular slime mold Physarum polycephalum is a gigantic single cell visible to the unaided eye. The cell shows a rich spectrum of behavioral patterns in response to environmental conditions. In a series of simple experiments we demonstrate how to make computing, sensing, and actuating devices from the slime mold. We show how to program living slime mold machines by configurations of repelling and attracting gradients and demonstrate the workability of the living machines on tasks of computational geometry, logic, and arithmetic. PMID:23834592

  4. Re-ordering a Border Space: Relief, Rehabilitation, and Nation-Building in North- Eastern India after the 1950 Assam Earthquake

    E-print Network

    Guyot-Réchard, Bérénice

    2015-04-08

    to be aseismic.7 Yet if the 1897 disaster was bad enough, the 1950 earthquake was a cataclysm of even greater proportions. At the time, the latter ranked as the fifth biggest tremor ever recorded.8 Newspapers likened it to a gigantic atomic bomb.9... ://earthquake.usgs.gov/earthquakes/world/10_largest_world.php [accessed 18 March 2014]. 9 'Assam earthquake released 1,000,000 times more energy than atom bomb', The Assam Tribune (28 April 1951). 3 come. When these natural dams burst, the water engulfed the countryside, and rivers...

  5. Microwave Magnetochiral Effect in Cu2OSeO3

    NASA Astrophysics Data System (ADS)

    Mochizuki, Masahito

    2015-05-01

    We theoretically find that in the multiferroic chiral magnet Cu2OSeO3 resonant magnetic excitations are coupled to the collective oscillation of the electric polarization, and thereby attain simultaneous activity to the ac magnetic field and ac electric field. Because of the interference between these magnetic and electric activation processes, this material hosts a gigantic magnetochiral dichroism for microwaves, that is, a directional dichroism at gigahertz frequencies in the Faraday geometry. The absorption intensity of a microwave differs by as much as ˜30 % depending on whether its propagation direction is parallel or antiparallel to the external magnetic field.

  6. MACRODYSTROPHIA LIPOMATOSA WITH ULNAR DISTRIBUTION IN HAND: MR EVALUATION OF A RARE DISORDER.

    PubMed

    Siddiqui, M Azfar; Ahmad, M; Redhu, N; Ahmad, I; Ullah, E

    2015-01-01

    Macrodystrophia lipomatosa is a rare, non-hereditary congenital anomaly characterized by localised gigantism in the form of macrodactyly affecting a part of limb and rarely entire limb due to overgrowth of all mesenchymal elements. Radiological and pathological hallmark is the disproportionate fibroadipose tissue proliferation in subcutaneous tissue, nerve sheaths, and periosteum that lead to soft tissue and bony enlargement. We present the case of a twenty years old female who presented with history of gradual enlargement of the medial aspect of right hand along ulnar nerve distribution since birth. MRI showed hypertrophy of bones and soft tissue with fatty proliferation, leading to the diagnosis of macrodystrophia lipomatosa. PMID:26223066

  7. Beckwith-Wiedemann syndrome with overlapping Perlman syndrome manifestation.

    PubMed

    Ferianec, Vladimír; Bartova, Michaela

    2014-10-01

    Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome known as exomphalos-macroglossia - gigantism syndrome. Prognosis is good, prenatal diagnosis is important for pregnancy management but might be difficult due to clinical overlap with other syndromes. Perlman syndrome is an overgrowth syndrome with high perinatal mortality, most frequent antenatal findings include polyhydramnios, macrosomia, visceromegaly, nephromegaly and foetal ascites. Authors present a case of prenatally diagnosed BWS with severe ascites as first antenatal finding and lethal course, signs more typical of Perlman syndrome. This combination of clinical signs has not been published yet and may contribute to specification of possible prenatal manifestation of BWS. PMID:24215131

  8. Vignettes from the history of overgrowth and related syndromes.

    PubMed

    Beckwith, J B

    1998-10-01

    Vignettes of several stages in the evolution of present concepts of overgrowth and related syndromes are presented. The scientific study of this topic did not begin until the 18th century because of its delayed emergence from superstition and fallacy. Examples of early superstitions concerning gigantism are presented, with some historical comments on infant giants. The pioneering contributions of Isodore Geoffroy Saint-Hilaire to the scientific analysis of overgrowth are emphasized. Details concerning the early history of the growth syndrome associated with the names of Wiedemann and Beckwith is presented, with emphasis on cases reported prior to ours. PMID:9781902

  9. Bursting money bins, the ice and water structure

    NASA Astrophysics Data System (ADS)

    Bagnoli, Franco

    2015-05-01

    In the classic comics by Carl Barks, "The Big Bin on Killmotor Hill" [1], Uncle Scrooge, trying to defend his money bin from the Beagle Boys, follows a suggestion by Donald Duck, and fills the bin with water. Unfortunately, that night is going be the coldest one in the history of Ducksburg. The water freezes, bursting the "ten-foot walls'' of the money bin, and finally the gigantic cube of ice and dollars slips down the hill up to the Beagle Boys lot.

  10. Controls on size and occurrence of the largest sub-aerial landslide on Earth: Seymareh (Saidmarreh) landslide, Zagros fold-thrust belt, Iran

    NASA Astrophysics Data System (ADS)

    Roberts, N. J.; Evans, S. G.

    2009-12-01

    Gigantic (> 1 Gm3) landslides are high-magnitude, low-frequency extremes of mass movements. They are important factors in topographic evolution and hazard in mountain regions due to their magnitude. However, few examples exist for study because of their infrequency. Consequently, controls on the location and size gigantic landslides remain poorly understood. Re-examination of the Seymareh (Saidmarreh) rock avalanche, Zagros fold-thrust belt, shows it to be the largest sub-aerial landslide on Earth (initial failure volume 38 Gm3), thus representing the upper magnitude limit for terrestrial landslides. Detailed examination of the source area (including orbital remote sensing, geotechnical investigation and structural mapping) provides new insights into controls on the size and mobility of gigantic landslides. The gigantic Early Holocene rockslide initiated on the northeast limb of Kabir Kuh, the largest anticline in the Zagros fold-thrust belt, and involved the simultaneous failure of a rock mass measuring 15 km along strike. The rockslide transformed into a rock avalanche that ran-out 19.0 km, filling two adjacent valleys and overtopping an intervening low mountain ridge. The failure involved 220 m of competent jointed limestone (Asmari Formation) underlain by 580 m of weaker mudrock-dominated units. Geologic structure, geomechanical strength and topography of the source slope strongly controlled failure initiation. Extreme landslide dimensions resulted in part from extensive uniform pre-failure stability, produced by structural and topographic features related to the large scale of the Kabir Kuh anticline. High continuity bedding planes determined the large lateral extent along strike. Bedding normal joints, the breached nature of the anticline and fluvial undercutting at the slope toe accommodated expansive lateral, headscarp and toe release, respectively, necessary for extensive failure. Geomechanically weak units at depth aided the penetration of the failure surface into the source slope while low bedding dip (ca. 19°) allowed kinematic freedom of a particularly thick sequence to move downslope. Prevention of gradual rockmass removal by smaller-magnitude, more frequent denudation ensured its preservation for later simultaneous failure. The overall failure surface (11°) cut across weaker beds and finally breached the Asmari carapace by break-out at the base of the source slope. Relative relief of the source slope on Kabir Kuh was modest (1350 m on average) indicating that uniform structural and topographic conditions along strike, shallow bedding dips, and the geomechnical properties of the source rock mass were more important in determining the magnitude of the landslide that forms the upper magnitude limit for subaerial landslides.

  11. Ar-40 to Ar-39 dating of pseudotachylites from the Witwatersrand basin, South Africa, with implications for the formation of the Vredefort Dome

    NASA Technical Reports Server (NTRS)

    Trieloff, M.; Kunz, J.; Jessberger, E. K.; Reimold, W. U.; Boer, R. H.; Jackson, M. C.

    1992-01-01

    The formation of the Vredefort Dome, a structure in excess of 100 km in diameter and located in the approximate center of the Witwatersrand basin, is still the subject of lively geological controversy. It is widely accepted that its formation seems to have taken place in a single sudden event, herein referred to as the Vredefort event, accompanied by the release of gigantic amounts of energy. It is debated, however, whether this central event was an internal one, i.e., a cryptoexplosion triggered by volcanic or tectonic processes, or the impact of an extraterrestrial body. The results of this debate are presented.

  12. Far-Infrared Optical Response of Neutral-Ionic Phase Transition in an Organic Charge-Transfer Complex

    NASA Astrophysics Data System (ADS)

    Okimoto, Y.; Horiuchi, S.; Saitoh, E.; Kumai, R.; Tokura, Y.

    2001-10-01

    Infrared optical spectra have been investigated for a charge-transfer complex of tetrathiafulvalene and 2-bromo-3,5,6-trichloro- p-benzoquinone, which undergoes a neutral-ionic ( N-I) transition at Tc = 68 K. With the decrease of temperature toward Tc, the far-infrared reflectivity spectrum is gradually transformed into a Drude-like high reflectance band edging around 100 cm-1, and the optical conductivity shows an anomalous peak around 10 cm-1. The far-infrared anomaly is related to the gigantic dielectric response just above Tc, which are both discussed in terms of dynamics of N-I domain walls with fractional charge.

  13. Design of a Template for Handwriting Based Hindi Text Entry in Handheld Devices

    NASA Astrophysics Data System (ADS)

    Gangopadhyay, Diya; Vasal, Ityam; Yammiyavar, Pradeep

    Mobile phones, in the recent times, have become affordable and accessible to a wider range of users including the hitherto technologically and economically under-represented segments. Indian users are a gigantic consumer base for mobile phones. With Hindi being one of the most widely spoken languages in the country and the primary tool of communication for about a third of its population, an effective solution for Hindi text entry in mobile devices is expected to be immensely useful to the non English speaking users. This paper proposes a mobile phone handwriting based text entry solution for Hindi language, which allows for an easy text entry method, while facilitating better recognition accuracy.

  14. Generation-X Mission Technology Drivers

    NASA Technical Reports Server (NTRS)

    Zhang, Will

    2004-01-01

    Gen-X is envisioned to be an observatory with a gigantic X-ray collection area and exquisite angular resolution and energy spectral resolution. As such it presents a number of technological challenges: extremely lightweight X-ray optics, large area and fast readout imaging detectors with excellent energy resolution, and efficient gratings. These challenges call for development of both the basic technologies and large-scale precision manufacture techniques. In this paper we present and discuss these challenges and outline a plan that will address these challenges in the next two decades.

  15. The Final Proceedings of the DOE/NASA Solar Power Satellite Program Review

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The solar power satellite (SPS) concept defined as 'placing gigantic satellites in geosynchronous orbit to capture sunlight, changing the energy into an appropriate form for transmission to Earth, and introducing the energy into the electric power grid' is evaluated in terms of costs and benefits. The concept development and evaluation program is reviewed in four general areas: systems definition; environmental; societal; and comparative assessments. Specific factors addressed include: transportation, construction in space, methods of conversion of sunlight into energy, transmission to Earth, maintenance in orbit and decommissioning of satellites; environmental, political, and economic effects; and comparison of SPS to other forms of power generation, both terrestrial and in space.

  16. Large space structures - Fantasies and facts

    NASA Technical Reports Server (NTRS)

    Card, M. F.; Boyer, W. J.

    1980-01-01

    A review of large space structures activities from 1973 to 1979 is presented. Long-range studies of space colonies, gigantic solar power stations and projected earth applications revived interest in space activities. Studies suggest opportunities for advanced antenna and platform applications. Matching low-thrust propulsion to large flexible vehicles will be a key technology. Current structures technology investigations include deployable and erectable structures and assembly techniques. Based on orbited structures experience, deployment reliability is a critical issue for deployable structures. For erectable structures, concepts for earth-fabricated and space-fabricated memb

  17. Collagen fibre implant for tendon and ligament biological augmentation. In vivo study in an ovine model

    E-print Network

    Enea, D.; Gwynne, J.; Kew, S.; Arumugam, M.; Shepherd, J.; Brooks, R.; Ghose, S.; Best, Serena Michelle; Cameron, Ruth Elizabeth; Rushton, N.

    2012-06-20

    between the fibres appeared more cel- lular and more vascular (Fig. 5g, j) than the normal tendon tissue. It was mainly composed of tendon fibroblasts, with a few polymorphonuclear cells and multinuclear cells adhering on the fibres (Fig. 5k). In both... properties. J Mater Sci Mater Med 22:1569–1578 11. Fan H, Liu H, Toh SL, Goh JC (2009) Anterior cruciate ligament regeneration using mesenchymal stem cells and silk scaffold in large animal model. Biomaterials 30:4967–4977 12. Gigante A, Cesari E, Busilacchi...

  18. The cosmic origin of supersymmetry and internal symmetry

    E-print Network

    Ding-Yu Chung

    2001-02-06

    The cosmic vacuum is the wavefunction of the eleven dimensional Planck supermembrane. The Planck wavefunction is the superposition of dimensions from eleven to four dimensional spacetime with decreasing energy and increasing size. The cosmic vacuum is a gigantic cosmic particle-wave. It undergoes a gigantic slow cosmic oscillation between the high-energy eleven dimensional spacetime and the low-energy four dimensional spacetime. The origin of ordinary (baryonic) matter in the big bang universe is the collapsed Planck wavefunction due to the lepton-quark entangled state with two unequal sets of spacetime as the quantum system-measurement entangled state in Hilbert space. The collapsed Planck wavefunction has four dimensional spacetime and seven dimensional internal space (non-spacetime) with seven gauge bosons. The remnants of the cosmic oscillation are cosmic radiation, gravity, and microscopic particle-wave in the four dimensional spacetime. Internal symmetries for gauge bosons, leptons, quarks, and black holes are in the seven dimensional internal space. The result is the big bang universe with the cosmic vacuum. The cosmic vacuum has the four-to-eleven dimensional spacetime supersymmetry, while the big bang universe has the four dimensional spacetime and the seven dimensional internal space. The masses of elementary particles can be calculated with only four known constants: the number of the extra spatial dimensions in the supermembrane, the mass of electron, the mass of Z, and the fine structure constant for the magnetic field.

  19. View of Jupiter

    NASA Technical Reports Server (NTRS)

    1975-01-01

    This view of Jupiter shows the giant planet's cloud tops taken by the Pioneer 10 spacecraft as it flew past Jupiter last December. This view was taken from 2,695,000 kilometers (1,842,451 miles) away. It shows the 25,000 mile long Great Red Spot, which is large enough to swallow up several Earths. Individual cloud formations are visible in some detail. The bright zones appear to become split up into the detailed flow patterns of Jupiter's atmosphere and clouds. The area surrounding the Spot in the bright South Tropical Zone, suggests a flow pattern about the Spot which is bulged toward the north by the Spot. The Spot may be a gigantic 'permanent hurricane.' The gigantic cloud swirls are thousands or more miles across. Pioneer 10 flew past Jupiter in December 1974 and flew past the orbit of Pluto in 1987. A sister spacecraft, Pioneer 11 reached Jupiter in December 1975. The Pioneer Project was managed by NASA's Ames Research Center, Mountain View, Calafornia. The spacecraft was built by TRW Systems.

  20. Saturn's north temperate region

    NASA Technical Reports Server (NTRS)

    1981-01-01

    This comparison shows Saturn's north temperate region as viewed Nov. 5, 1980, by Voyager 1 (left) and Aug. 21 by its sister craft, Voyager 2, from a range of 5 million kilometers (3.1 million miles). The large bright oval feature in the lower right of each frame measures about 2,500 km. (1,550 mi.) across. This feature, a gigantic storm system in the planet's atmosphere, was first observed by Voyager 1 almost exactly one year ago. Thus, as on Jupiter, some storms in Saturn's atmosphere are quite long-lived compared to their smaller terrestrial counterparts. By contrast, the pattern of convective disturbances to the north (upper right) undergoes rapid changes in a matter of even a few days. In some respects, these features resemble gigantic thunderstorms. The largest bright feature in the Voyager 1 photograph extends about 7,500 km. (4,650 mi.) from north to south. These giant storms lie within one of the strongest westward-flowing currents observed in the atmosphere, with wind speeds of about 20 meters-per-second (45 mph). The smallest visible features here are about 100 km. (62 mi.) across. The Voyager project is managed for NASA by the Jet Propulsion Laboratory, Pasadena, Calif.

  1. Genomic comparison of closely related Giant Viruses supports an accordion-like model of evolution

    PubMed Central

    Filée, Jonathan

    2015-01-01

    Genome gigantism occurs so far in Phycodnaviridae and Mimiviridae (order Megavirales). Origin and evolution of these Giant Viruses (GVs) remain open questions. Interestingly, availability of a collection of closely related GV genomes enabling genomic comparisons offer the opportunity to better understand the different evolutionary forces acting on these genomes. Whole genome alignment for five groups of viruses belonging to the Mimiviridae and Phycodnaviridae families show that there is no trend of genome expansion or general tendency of genome contraction. Instead, GV genomes accumulated genomic mutations over the time with gene gains compensating the different losses. In addition, each lineage displays specific patterns of genome evolution. Mimiviridae (megaviruses and mimiviruses) and Chlorella Phycodnaviruses evolved mainly by duplications and losses of genes belonging to large paralogous families (including movements of diverse mobiles genetic elements), whereas Micromonas and Ostreococcus Phycodnaviruses derive most of their genetic novelties thought lateral gene transfers. Taken together, these data support an accordion-like model of evolution in which GV genomes have undergone successive steps of gene gain and gene loss, accrediting the hypothesis that genome gigantism appears early, before the diversification of the different GV lineages. PMID:26136734

  2. Adaptation to long sperm in Drosophila: correlated development of the sperm roller and sperm packaging.

    PubMed

    Joly, Dominique; Luck, Nathalie; Dejonghe, Béatrice

    2008-03-15

    Sperm are generally small and produced in huge numbers, but some species combine exaggerated sperm length with extremely limited numbers of sperm, an evolutionary trend that deviates from the theory of anisogamy. Sperm gigantism has arisen recurrently in various species, but insects exhibit the longest sperm, with some species of the Drosophilidae family producing sperm up to 6 cm in length. The anatomical, cytological, and physiological requirements for males to cope with these giant sperm were hitherto poorly understood. In this paper, we investigate the internal morphology of the male reproductive tract, and highlight specific features that may be linked to this increase in sperm size. We focus on species in the repleta group, within which sperm length varies by a factor of 35. An associated development of the sperm roller, a special twisting device inserted between the testis and the seminal vesicle, is demonstrated. Its length and the number of coils involved increase with sperm size, and it allows individual sperm to swell and roll into a spermatic pellet before reaching the seminal vesicle. This process occurs independently of and in addition to the sperm bundle coiling that takes place at the base of the testis. It is suggested that the emergence and development of the sperm roller may be a male adaptation to sperm gigantism. PMID:17377954

  3. Chromosome evolution with naked eye: Palindromic context of the life origin

    NASA Astrophysics Data System (ADS)

    Larionov, Sergei; Loskutov, Alexander; Ryadchenko, Eugeny

    2008-03-01

    Based on the representation of the DNA sequence as a two-dimensional (2D) plane walk, we consider the problem of identification and comparison of functional and structural organizations of chromosomes of different organisms. According to the characteristic design of 2D walks we identify telomere sites, palindromes of various sizes and complexity, areas of ribosomal RNA, transposons, as well as diverse satellite sequences. As an interesting result of the application of the 2D walk method, a new duplicated gigantic palindrome in the X human chromosome is detected. A schematic mechanism leading to the formation of such a duplicated palindrome is proposed. Analysis of a large number of the different genomes shows that some chromosomes (or their fragments) of various species appear as imperfect gigantic palindromes, which are disintegrated by many inversions and the mutation drift on different scales. A spread occurrence of these types of sequences in the numerous chromosomes allows us to develop a new insight of some accepted points of the genome evolution in the prebiotic phase.

  4. ["Die grosse Barb" in the museum of the University of Marburg. An early documentation of acromegaly].

    PubMed

    Krause, W; Rassner, G; Happle, R

    2009-06-01

    The university museum for cultural history in the castle of Marburg has a portrait "Die grosse Barb", which represents a women suffering from acromegaly. She shows the typical pathologic alterations: thickening of the skin folds, thickening of the lips and the eyelids, growth of bones and cartilages, lengthening of the nose, enlargement of the ears, protrusion of the zygoma, mandible and the chin. Acromegaly is a consequence of enhanced secretion of growth hormone, which occurs also as a symptom of several syndromes, such as multiple endocrine neoplasia type 1, McCune-Albright-syndrome, and NAME syndrome (Carney complex type I). The most remarkable symptom of acromegaly is the gigantism. This occurs also in androgen-deficient states, such as the Klinefelter syndrome and some more genetic syndromes, of which the Simpson-Golabi-Behmel syndrome, the Sotos syndrome, the Marfan syndrome, the homocystinuria, and the fragile X-syndrome may be mentioned. Nothing is known on the further fate of the patient shown in the portrait. It is also unknown, whether she owes her position as a chambermaid to her gigantism, for it was a common use in courts to have people with abnormal body shapes in attendance. PMID:19543868

  5. The maintenance of hybrids by parasitism in a freshwater snail.

    PubMed

    Guttel, Yonathan; Ben-Ami, Frida

    2014-11-01

    Hybrids have often been labelled evolutionary dead-ends due to their lower fertility and viability. However, there is growing awareness that hybridisation between different species may play a constructive role in animal evolution as a means to create variability. Thus, hybridisation and introgression may contribute to adaptive evolution, for example with regards to natural antagonists (parasites, predators, competitors) and adaptation to local environmental conditions. Here we investigated whether parasite intensity contributes to the continuous recreation of hybrids in 74 natural populations of Melanopsis, a complex of freshwater snails with three species. We also examined, under laboratory conditions, whether hybrids and their parental taxa differ in their tolerance of low and high temperatures and salinity levels. Infections were consistently less prevalent in males than in females, and lower in snails from deeper habitats. Infection prevalence in hybrids was significantly lower than in the parental taxa. Low hybrid infection rates could not be explained by sediment type, snail density or geographic distribution of the sampling sites. Interestingly, infected hybrid snails did not show signs of parasite-induced gigantism, whereas all parental taxa did. We found that hybrids mostly coped with extreme temperatures and salinity levels as well as their parental taxa did. Taken together, our results suggest that Melanopsis hybrids perform better in the presence of parasites and environmental stress. This may explain the widespread and long-term occurrence of Melanopsis hybrids as evidenced by paleontological and biogeographic data. Hybridisation may be an adaptive host strategy, reducing infection rates and resisting gigantism. PMID:25173837

  6. Upward electrical discharges observed above Tropical Depression Dorian

    PubMed Central

    Liu, Ningyu; Spiva, Nicholas; Dwyer, Joseph R.; Rassoul, Hamid K.; Free, Dwayne; Cummer, Steven A.

    2015-01-01

    Observation of upward electrical discharges from thunderstorms has been sporadically reported in the scientific literature. According to their terminal altitudes, they are classified as starters (20–30?km), jets (40–50?km) and gigantic jets (70–90?km). They not only have a significant impact on the occupied atmospheric volumes but also electrically couple different atmospheric regions. However, as they are rare and unpredictable, our knowledge of them has been built on observations that typically record only one type of such discharges. Here we report a close-distance observation of seven upward discharges including one starter, two jets and four gigantic jets above Tropical Depression Dorian. Our optical and electromagnetic data indicate that all events are of negative polarity, suggesting they are initiated in the same thundercloud charge region. The data also indicate that the lightning-like discharge channel can extend above thunderclouds by about 30?km, but the discharge does not emit low-frequency electromagnetic radiation as normal lightning. PMID:25607345

  7. Permittivity spectroscopy - an insight into materials properties.

    PubMed

    Stoynov, Zdravko; Mladenova, Emiliya; Levi, Daniela; Vladikova, Daria

    2014-01-01

    Permittivity Spectroscopy is a branch of the Impedance Spectroscopy specially tuned for measurements and analyses of dielectrics permittivity properties. The present paper presents experimental results on permittivity properties of composite objects in which a polarizable dielectric is distributed in a fine non-polarizable matrix (solid or liquid) measured in frequency range 1 MHz down to 0.01 Hz. Two types of objects are studied - water in porous functional ceramics and lubricating oils. In both systems gigantic enhancement of the effective capacitance is observed. The first series of experiments was performed on porous membranes of yttrium doped barium cerate, which is a proton conducting ceramics with hydrophilic properties. At a given level of watering the measured capacitance is sharply increasing (3 to 5 orders of magnitude) in the lower frequency range. The second example covers permittivity study of lubricating oils, where the increase is 2-3 orders of magnitude. The phenomenon of gigantic enhancement of the effective capacitance could be related to a formation of dipole volume structures induced by the external alternating electrical field. PMID:25125108

  8. Upward electrical discharges observed above Tropical Depression Dorian.

    PubMed

    Liu, Ningyu; Spiva, Nicholas; Dwyer, Joseph R; Rassoul, Hamid K; Free, Dwayne; Cummer, Steven A

    2015-01-01

    Observation of upward electrical discharges from thunderstorms has been sporadically reported in the scientific literature. According to their terminal altitudes, they are classified as starters (20-30?km), jets (40-50?km) and gigantic jets (70-90?km). They not only have a significant impact on the occupied atmospheric volumes but also electrically couple different atmospheric regions. However, as they are rare and unpredictable, our knowledge of them has been built on observations that typically record only one type of such discharges. Here we report a close-distance observation of seven upward discharges including one starter, two jets and four gigantic jets above Tropical Depression Dorian. Our optical and electromagnetic data indicate that all events are of negative polarity, suggesting they are initiated in the same thundercloud charge region. The data also indicate that the lightning-like discharge channel can extend above thunderclouds by about 30?km, but the discharge does not emit low-frequency electromagnetic radiation as normal lightning. PMID:25607345

  9. Development of high purity large forgings for nuclear power plants

    NASA Astrophysics Data System (ADS)

    Tanaka, Yasuhiko; Sato, Ikuo

    2011-10-01

    The recent increase in the size of energy plants has been supported by the development of manufacturing technology for high purity large forgings for the key components of the plant. To assure the reliability and performance of the large forgings, refining technology to make high purity steels, casting technology for gigantic ingots, forging technology to homogenize the material and consolidate porosity are essential, together with the required heat treatment and machining technologies. To meet these needs, the double degassing method to reduce impurities, multi-pouring methods to cast the gigantic ingots, vacuum carbon deoxidization, the warm forging process and related technologies have been developed and further improved. Furthermore, melting facilities including vacuum induction melting and electro slag re-melting furnaces have been installed. By using these technologies and equipment, large forgings have been manufactured and shipped to customers. These technologies have also been applied to the manufacture of austenitic steel vessel components of the fast breeder reactors and components for fusion experiments.

  10. Heat storage in Asian elephants during submaximal exercise: behavioral regulation of thermoregulatory constraints on activity in endothermic gigantotherms.

    PubMed

    Rowe, M F; Bakken, G S; Ratliff, J J; Langman, V A

    2013-05-15

    Gigantic size presents both opportunities and challenges in thermoregulation. Allometric scaling relationships suggest that gigantic animals have difficulty dissipating metabolic heat. Large body size permits the maintenance of fairly constant core body temperatures in ectothermic animals by means of gigantothermy. Conversely, gigantothermy combined with endothermic metabolic rate and activity likely results in heat production rates that exceed heat loss rates. In tropical environments, it has been suggested that a substantial rate of heat storage might result in a potentially lethal rise in core body temperature in both elephants and endothermic dinosaurs. However, the behavioral choice of nocturnal activity might reduce heat storage. We sought to test the hypothesis that there is a functionally significant relationship between heat storage and locomotion in Asian elephants (Elephas maximus), and model the thermoregulatory constraints on activity in elephants and a similarly sized migratory dinosaur, Edmontosaurus. Pre- and post-exercise (N=37 trials) measurements of core body temperature and skin temperature, using thermography were made in two adult female Asian elephants at the Audubon Zoo in New Orleans, LA, USA. Over ambient air temperatures ranging from 8 to 34.5°C, when elephants exercised in full sun, ~56 to 100% of active metabolic heat production was stored in core body tissues. We estimate that during nocturnal activity, in the absence of solar radiation, between 5 and 64% of metabolic heat production would be stored in core tissues. Potentially lethal rates of heat storage in active elephants and Edmontosaurus could be behaviorally regulated by nocturnal activity. PMID:23785105

  11. The Climatic Observatory of the Karst (O.C.C.), a scientific facility within an important tourist framework

    NASA Astrophysics Data System (ADS)

    Colucci, R. R.; Micheletti, S.; Fabbo, R.

    2009-09-01

    The Climatic Observatory of the Karst, officially inaugurated on 2nd October, 2008, is born in the same place of the historical headquarter of the Borgo Grotta Gigante Meteorological Office, which was set up in 1966 and has been officially operating since 1st January, 1967. The meteorological facilities and the weather office are located on the premises of the visitor centre of "Grotta Gigante”, which is a very popular karstic cave of Trieste, visited each year by at least 70k people. The privileged position induced the promoters of this initiative to think about an integrated meteorological multilanguages system for the visitors. This system provides in real time weather forecasts and meteorological data and, at the same time, general tourist information as well. The synergic cooperation of various Scientific Organizations, which are involved in climatic research at the Borgo Grotta Gigante Climatic Observatory of the Karst, makes possible the realization of this project: "E.Boegan” Cave Commission of S.A.G. (the administrative body); ARPA-OSMER, the Friuli Venezia-Giulia Meteorological Observatory of the Regional Agency of the Environmental Protection, (which manages the automatic station, broadcasts and publishes data in real time and forecasts in the visitors waiting room); C.N.R.-I.S.M.A.R., the Marine Science Institute in Trieste of the National Research Council of Italy (which manages and maintains mechanical instruments, publishes data and carries out checks, files data and publishes reports); U.M.F.V.G., the Friuli Venezia Giulia Meteorological Union (which is involved in scientific dissemination activity and web sharing of information); the Environmental and Public Works Section and Water Service of the Friuli Venezia Giulia Region (water resources monitoring). Moreover one of the main characteristic of the Observatory, also because of didactic reasons, is to maintain the traditional mechanical-analogue part of data collection, carried out by observers, alongside the electronic sensors. This factor is essential for the continuity and the homogeneity of historical series and it distinguishes the observatory from a normal weather station. The data collected is published annually in the "Osservazioni meteoriche" magazine, a publication edited by CGEB as a supplement to the scientific journal "Atti e memorie", which is sent to various Public Authorities, Scientific Organizations, libraries and anyone who applies for it.

  12. Hypomethylation of the H19 Gene Causes Not Only Silver-Russell Syndrome (SRS) but Also Isolated Asymmetry or an SRS-Like Phenotype

    PubMed Central

    Bliek, Jet; Terhal, Paulien; van den Bogaard, Marie-José; Maas, Saskia; Hamel, Ben; Salieb-Beugelaar, Georgette; Simon, Marleen; Letteboer, Tom; van der Smagt, Jasper; Kroes, Hester; Mannens, Marcel

    2006-01-01

    The H19 differentially methylated region (DMR) controls the allele-specific expression of both the imprinted H19 tumor-suppressor gene and the IGF2 growth factor. Hypermethylation of this DMR—and subsequently of the H19 promoter region—is a major cause of the clinical features of gigantism and/or asymmetry seen in Beckwith-Wiedemann syndrome or in isolated hemihypertrophy. Here, we report a series of patients with hypomethylation of the H19 locus. Their main clinical features of asymmetry and growth retardation are the opposite of those seen in patients with hypermethylation of this region. In addition, we show that complete hypomethylation of the H19 promoter is found in two of three patients with the full clinical spectrum of Silver-Russell syndrome. This syndrome is also characterized by growth retardation and asymmetry, among other clinical features. We conclude that patients with these clinical features should be analyzed for H19 hypomethylation. PMID:16532391

  13. Bilateral Renal Dysplasia, Nephroblastomatosis, and Bronchial Stenosis. A New Syndrome?

    PubMed Central

    Rodriguez, Maria Matilde; Correa-Medina, Mayrin; Whittington, Elizabeth E.

    2015-01-01

    Bilateral nephroblastomatosis (NB) is an uncommon renal anomaly characterized by multiple confluent nephrogenic rests scattered through both kidneys, with only a limited number of cases reported in the medical literature. Some of these children may have associated either Perlman or Beckwith–Wiedemann syndrome and others do not demonstrate syndromic features. We report a full-term boy with anteverted nose, bilateral bronchial stenosis due to lack of cartilage, bilateral obstructive renal dysplasia and NB with glomeruloid features. The infant had visceromegaly, but neither gigantism nor hemihypertrophy. Immunohistochemistry for PAX2 (Paired box gene-2) and WT-1 (Wilms Tumor 1) were strongly positive in the areas of NB. GLEPP-1 (Glomerular Epithelial Protein) did not stain the areas of NB with a glomeruloid appearance, but was positive in the renal glomeruli as expected. We found neither associated bronchial stenosis nor the histology of NB resembling giant glomeruli in any of the reported cases of NB. PMID:25871299

  14. Bilateral renal dysplasia, nephroblastomatosis, and bronchial stenosis. A new syndrome?

    PubMed

    Rodriguez, Maria Matilde; Correa-Medina, Mayrin; Whittington, Elizabeth E

    2015-06-01

    Bilateral nephroblastomatosis (NB) is an uncommon renal anomaly characterized by multiple confluent nephrogenic rests scattered through both kidneys, with only a limited number of cases reported in the medical literature. Some of these children may have associated either Perlman or Beckwith-Wiedemann syndrome and others do not demonstrate syndromic features. We report a full-term boy with anteverted nose, bilateral bronchial stenosis due to lack of cartilage, bilateral obstructive renal dysplasia and NB with glomeruloid features. The infant had visceromegaly, but neither gigantism nor hemihypertrophy. Immunohistochemistry for PAX2 (Paired box gene-2) and WT-1 (Wilms Tumor 1) were strongly positive in the areas of NB. GLEPP-1 (Glomerular Epithelial Protein) did not stain the areas of NB with a glomeruloid appearance, but was positive in the renal glomeruli as expected. We found neither associated bronchial stenosis nor the histology of NB resembling giant glomeruli in any of the reported cases of NB. PMID:25871299

  15. Being, space and time in the Web

    E-print Network

    Vafopoulos, Michalis

    2011-01-01

    The Web emerged as the antidote to rapidly increasing quantity of accumulated knowledge because it successfully enables massive representation and communication with minimum costs. Despite the fact that its gigantic scale and impact make difficult to anticipate the effects in humans, we claim from it to be fast, secure, reliable, all-inclusive and trustworthy. It is time for science to compensate and provide an epistemological "antidote" to these issues. On this campaign, Philosophy should be in the front line by forming the relevant questions. We initiate the dialogue for a theory about being in the Web that will serve as a bridge between philosophical thinking and engineering. We analyze existence and spatiotemporality in the Web, as a closed techno-social system, and how it transforms the traditional conceptions about actuality. Location in the Web space is specified by the Web being's URI and the URI's of incoming and outgoing links. The primer role of visiting durations is best approximated by Bergsonian...

  16. [Indications for surgical treatment of hard scarring gastric ulcers].

    PubMed

    Durleshter, V M; Korochanskaia, N V; Serikova, S N

    2014-01-01

    It was done the comparative analysis of the morphofunctional state of the upper gastrointestinal tract between 350 patients with effective conservative treatment and 104 patients with hard scarring gastric ulcers. The analysis identified the predictors of ineffective medical treatment and led to deliver the indications for timely surgical treatment. It was identified the next indications for planned organ-preserving surgical treatment of patients with hard scarring gastric ulcers: penetrating and non-healing ulcers with large or gigantic size in case of the adequate medical therapy, high-grade dysplasia and colonic metaplasia of the gastric epithelium in the borders or fundus of the ulcer,ulcers combination with fixed cardio-fundal or fundo-corporal hiatal hernias; hypotonic-hypokinetic type of the gastric and duodenal activity with the development of gastrostasis and pronounced duodenogastric reflux. PMID:24781063

  17. How hottest geometries and adsorptive parameters influence the SER(R)S spectra of Methylene Blue molecules adsorbed on nanocolloidal gold particles of varied sizes?

    PubMed

    Roy, Sannak Dutta; Ghosh, Manash; Chowdhury, Joydeep

    2015-12-01

    The SER(R)S spectra of Methylene Blue (MB) molecule adsorbed on gold nanocolloidal particles (AuNCs) have been investigated. The adsorptive parameters of the molecule adsorbed on AuNCs have been evaluated with the aid of Fluorescence Spectroscopy study. Fluorescence spectroscopic studies have been further applied to understand the concentration of probe molecule actually adsorbed on AuNC surfaces. Gigantic enhancements ?10(6)-10(16) orders of magnitude have been recorded for the enhanced Raman bands in the SER(R)S spectra. Three-dimensional Finite Difference Time Domain (3D-FDTD) simulations studies have been carried out to predict the distributions of electric fields around the possible nanoaggregated hot geometries considered to be responsible for the huge enhancements of SER(R)S bands of the MB molecule. PMID:26172467

  18. Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

    PubMed Central

    Lawrence, Sara L.; Feil, Susanne C.; Morton, Craig J.; Farrand, Allison J.; Mulhern, Terrence D.; Gorman, Michael A.; Wade, Kristin R.; Tweten, Rodney K.; Parker, Michael W.

    2015-01-01

    Pore-forming proteins are weapons often used by bacterial pathogens to breach the membrane barrier of target cells. Despite their critical role in infection important structural aspects of the mechanism of how these proteins assemble into pores remain unknown. Streptococcus pneumoniae is the world’s leading cause of pneumonia, meningitis, bacteremia and otitis media. Pneumolysin (PLY) is a major virulence factor of S. pneumoniae and a target for both small molecule drug development and vaccines. PLY is a member of the cholesterol-dependent cytolysins (CDCs), a family of pore-forming toxins that form gigantic pores in cell membranes. Here we present the structure of PLY determined by X-ray crystallography and, in solution, by small-angle X-ray scattering. The crystal structure reveals PLY assembles as a linear oligomer that provides key structural insights into the poorly understood early monomer-monomer interactions of CDCs at the membrane surface. PMID:26403197

  19. Competition and constraint drove Cope's rule in the evolution of giant flying reptiles.

    PubMed

    Benson, Roger B J; Frigot, Rachel A; Goswami, Anjali; Andres, Brian; Butler, Richard J

    2014-01-01

    The pterosaurs, Mesozoic flying reptiles, attained wingspans of more than 10 m that greatly exceed the largest birds and challenge our understanding of size limits in flying animals. Pterosaurs have been used to illustrate Cope's rule, the influential generalization that evolutionary lineages trend to increasingly large body sizes. However, unambiguous examples of Cope's rule operating on extended timescales in large clades remain elusive, and the phylogenetic pattern and possible drivers of pterosaur gigantism are uncertain. Here we show 70 million years of highly constrained early evolution, followed by almost 80 million years of sustained, multi-lineage body size increases in pterosaurs. These results are supported by maximum-likelihood modelling of a comprehensive new pterosaur data set. The transition between these macroevolutionary regimes is coincident with the Early Cretaceous adaptive radiation of birds, supporting controversial hypotheses of bird-pterosaur competition, and suggesting that evolutionary competition can act as a macroevolutionary driver on extended geological timescales. PMID:24694584

  20. Introduction to Plasma Dynamo, Reconnection and Shocks

    SciTech Connect

    Intrator, Thomas P.

    2012-08-30

    In our plasma universe, most of what we can observe is composed of ionized gas, or plasma. This plasma is a conducting fluid, which advects magnetic fields when it flows. Magnetic structure occurs from the smallest planetary to the largest cosmic scales. We introduce at a basic level some interesting features of non linear magnetohydrodynamics (MHD). For example, in our plasma universe, dynamo creates magnetic fields from gravitationally driven flow energy in an electrically conducting medium, and conversely magnetic reconnection annihilates magnetic field and accelerates particles. Shocks occur when flows move faster than the local velocity (sonic or Alfven speed) for the propagation of information. Both reconnection and shocks can accelerate particles, perhaps to gigantic energies, for example as observed with 10{sup 20} eV cosmic rays.

  1. Tetradecacobalt(II)-containing 36-niobate [Co14(OH)16(H2O)8Nb36O106]20- and its photocatalytic H2 evolution activity.

    PubMed

    Niu, Jingyang; Li, Fang; Zhao, Junwei; Ma, Pengtao; Zhang, Dongdi; Bassil, Bassem; Kortz, Ulrich; Wang, Jingping

    2014-08-01

    A gigantic Co14-containing 36-niobate, Na12K8[Co14(OH)16(H2O)8Nb36O106]?71H2O (1), has been prepared by the hydrothermal method and structurally characterized. Polyanion [Co14(OH)16(H2O)8Nb36O106](20-) (1?a) comprises a central Co7 core, surrounded by another seven isolated Co(2+) ions and six Lindqvist-type (Nb6O19) hexaniobate fragments. This is the first example of a high-nuclear cobalt-cluster-containing polyoxoniobate. The photocatalytic H2 evolution activity of Pt-loaded 1 was observed in methanol solution under irradiation using a 300?W Xe lamp. PMID:25043175

  2. Neutrino Radiation Showing a Christodoulou Memory Effect in General Relativity

    E-print Network

    Lydia Bieri; David Garfinkle

    2013-08-14

    We describe neutrino radiation in general relativity by introducing the energy-momentum tensor of a null fluid into the Einstein equations. Investigating the geometry and analysis at null infinity, we prove that a component of the null fluid enlarges the Christodoulou memory effect of gravitational waves. The description of neutrinos in general relativity as a null fluid can be regarded as a limiting case of a more general description using the massless limit of the Einstein-Vlasov system. The present authors with co-authors have work in progress to generalize the results of this paper using this more general description. Gigantic neutrino bursts occur in our universe in core-collapse supernovae and in the mergers of neutron star binaries.

  3. Mainland size variation informs predictive models of exceptional insular body size change in rodents.

    PubMed

    Durst, Paul A P; Roth, V Louise

    2015-07-01

    The tendency for island populations of mammalian taxa to diverge in body size from their mainland counterparts consistently in particular directions is both impressive for its regularity and, especially among rodents, troublesome for its exceptions. However, previous studies have largely ignored mainland body size variation, treating size differences of any magnitude as equally noteworthy. Here, we use distributions of mainland population body sizes to identify island populations as 'extremely' big or small, and we compare traits of extreme populations and their islands with those of island populations more typical in body size. We find that although insular rodents vary in the directions of body size change, 'extreme' populations tend towards gigantism. With classification tree methods, we develop a predictive model, which points to resource limitations as major drivers in the few cases of insular dwarfism. Highly successful in classifying our dataset, our model also successfully predicts change in untested cases. PMID:26085585

  4. On the fate of pumice rafts formed during the 2012 Havre submarine eruption

    PubMed Central

    Jutzeler, Martin; Marsh, Robert; Carey, Rebecca J.; White, James D. L.; Talling, Peter J.; Karlstrom, Leif

    2014-01-01

    Pumice rafts are floating mobile accumulations of low-density pumice clasts generated by silicic volcanic eruptions. Pumice in rafts can drift for years, become waterlogged and sink, or become stranded on shorelines. Here we show that the pumice raft formed by the impressive, deep submarine eruption of the Havre caldera volcano (Southwest Pacific) in July 2012 can be mapped by satellite imagery augmented by sailing crew observations. Far from coastal interference, the eruption produced a single >400?km2 raft in 1 day, thus initiating a gigantic, high-precision, natural experiment relevant to both modern and prehistoric oceanic surface dispersal dynamics. Observed raft dispersal can be accurately reproduced by simulating drift and dispersal patterns using currents from an eddy-resolving ocean model hindcast. For future eruptions that produce potentially hazardous pumice rafts, our technique allows real-time forecasts of dispersal routes, in addition to inference of ash/pumice deposit distribution in the deep ocean. PMID:24755668

  5. Slow and Steady: Ocean Circulation. The Influence of Sea Surface Height on Ocean Currents

    NASA Technical Reports Server (NTRS)

    Haekkinen, Sirpa

    2000-01-01

    The study of ocean circulation is vital to understanding how our climate works. The movement of the ocean is closely linked to the progression of atmospheric motion. Winds close to sea level add momentum to ocean surface currents. At the same time, heat that is stored and transported by the ocean warms the atmosphere above and alters air pressure distribution. Therefore, any attempt to model climate variation accurately must include reliable calculations of ocean circulation. Unlike movement of the atmosphere, movement of the ocean's waters takes place mostly near the surface. The major patterns of surface circulation form gigantic circular cells known as gyres. They are categorized according to their general location-equatorial, subtropical, subpolar, and polar-and may run across an entire ocean. The smaller-scale cell of ocean circulation is known' as an eddy. Eddies are much more common than gyres and much more difficult to track in computer simulations of ocean currents.

  6. Competition and constraint drove Cope's rule in the evolution of giant flying reptiles

    PubMed Central

    Benson, Roger B. J.; Frigot, Rachel A.; Goswami, Anjali; Andres, Brian; Butler, Richard J.

    2014-01-01

    The pterosaurs, Mesozoic flying reptiles, attained wingspans of more than 10?m that greatly exceed the largest birds and challenge our understanding of size limits in flying animals. Pterosaurs have been used to illustrate Cope’s rule, the influential generalization that evolutionary lineages trend to increasingly large body sizes. However, unambiguous examples of Cope’s rule operating on extended timescales in large clades remain elusive, and the phylogenetic pattern and possible drivers of pterosaur gigantism are uncertain. Here we show 70 million years of highly constrained early evolution, followed by almost 80 million years of sustained, multi-lineage body size increases in pterosaurs. These results are supported by maximum-likelihood modelling of a comprehensive new pterosaur data set. The transition between these macroevolutionary regimes is coincident with the Early Cretaceous adaptive radiation of birds, supporting controversial hypotheses of bird–pterosaur competition, and suggesting that evolutionary competition can act as a macroevolutionary driver on extended geological timescales. PMID:24694584

  7. Cloud Formation and Water Transport on Mars after Major Outflow Events

    NASA Technical Reports Server (NTRS)

    Santiago, D. L.; Colaprete, A.; Kreslavsky, M.; Kahre, M. A.; Asphaug, E.

    2012-01-01

    The triggering of a robust water cycle on Mars might have been caused by the gigantic flooding events evidenced by outflow channels. We use the Ames Mars General Circulation Model (MGCM) to test this hypothesis, studying how these presumably abrupt eruptions of water might have affected the climate of Mars in the past. We model where the water ultimately went as part of a transient atmospheric water cycle, to answer questions including: (1) Can sudden introductions of large amounts of water on the Martian surface lead to a new equilibrated water cycle? (2) What are the roles of water vapor and water ice clouds to sudden changes in the water cycle on Mars? (3) How are radiative feedbacks involved with this? (4) What is the ultimate fate of the outflow water? (5) Can we tie certain geological features to outflow water redistributed by the atmosphere?

  8. Control of Dzyaloshinskii-Moriya interaction in Mn(1-x)Fe(x)Ge: a first-principles study.

    PubMed

    Koretsune, Takashi; Nagaosa, Naoto; Arita, Ryotaro

    2015-01-01

    Motivated by the recent experiment on the size and helicity control of skyrmions in Mn(1-x)Fe(x)Ge, we study how the Dzyaloshinskii-Moriya (DM) interaction changes its size and sign in metallic helimagnets. By means of first-principles calculations, we successfully reproduce the non-trivial sign change of the DM interaction observed in the experiment. While the DM interaction sensitively depends on the carrier density or the detail of the electronic structure such as the size of the exchange splitting, its behavior can be systematically understood in terms of the distribution of anticrossing points in the band structure. By following this guiding principle, we can even induce gigantic anisotropy in the DM interaction by applying a strain to the system. These results pave the new way for skyrmion crystal engineering in metallic helimagnets. PMID:26304817

  9. Control of Dzyaloshinskii-Moriya interaction in Mn1?xFexGe: a first-principles study

    PubMed Central

    Koretsune, Takashi; Nagaosa, Naoto; Arita, Ryotaro

    2015-01-01

    Motivated by the recent experiment on the size and helicity control of skyrmions in Mn1?xFexGe, we study how the Dzyaloshinskii-Moriya (DM) interaction changes its size and sign in metallic helimagnets. By means of first-principles calculations, we successfully reproduce the non-trivial sign change of the DM interaction observed in the experiment. While the DM interaction sensitively depends on the carrier density or the detail of the electronic structure such as the size of the exchange splitting, its behavior can be systematically understood in terms of the distribution of anticrossing points in the band structure. By following this guiding principle, we can even induce gigantic anisotropy in the DM interaction by applying a strain to the system. These results pave the new way for skyrmion crystal engineering in metallic helimagnets. PMID:26304817

  10. Quantized topological Hall effect in skyrmion crystal

    NASA Astrophysics Data System (ADS)

    Hamamoto, Keita; Ezawa, Motohiko; Nagaosa, Naoto

    2015-09-01

    We theoretically study the quantized topological Hall effect (QTHE) in skyrmion crystal (SkX) without external magnetic field. The emergent magnetic field in SkX could be gigantic, as much as 4000 T , when its lattice constant is 1 nm . The band structure is not flat but has a finite gap in the low electron-density regime. We also study the conditions to realize the QTHE for the skyrmion size, carrier density, disorder strength, and temperature. Comparing the SkX and the system under the corresponding uniform magnetic field, the former is more fragile against the temperature compared with the latter since the gap is reduced by a factor of 1/5, while they are almost equally robust against the disorder. Therefore, it is expected that the QTHE of the SkX system is realized even with strong disorder at room temperature when the electron density is of the order of 1 per skyrmion.

  11. Saddlebags, Paperbacks and Mobile Media

    NASA Astrophysics Data System (ADS)

    Zwick, Carola

    Information is shaped by its format. The printing press with its repeatable layout laid ground for footnotes and references from other sources, and thus can be seen as the technology that initially generated the concept of hyperlinks. In the fifteenth century, printed matter quickly developed other formats like the paperback book or the flyer. These formats changed the content in almost every aspect significantly: books that fit in a saddlebag are mobile media and thus not as precious as the gigantic and prestigious folio placed on a lectern stand in a monastery. So books became a widespread, "ordinary" mobile medium and developed a multitude of purposes, aimed at different audiences, and generated a wide range of ideas for adequate content. The flyer in its limited size and public nature generated other forms of organizing and designing content: in order to fit the format and draw attention it uses a condensed form of messaging and an exaggerated typography.

  12. Petroleum, alcohol, and energy substitution in Brazil: Theoretical and empirical issues

    SciTech Connect

    Biller, D.

    1991-01-01

    As in other Latin American nations, the petroleum industry has always been surrounded by controversy in Brazil. Issues related to exploration, exploitation, and import of crude have received special attention by Brazilian decision makers. In the past decade, an additional relevant issue was brought into play by the oil crisis. An import substitution program for energy was implemented by the development of alternative indigenous energy sources. Among these sources, sugarcane was viewed as a reliable renewable resource for the production of fuel alcohol and, very recently, of electricity. Brazil engaged in a gigantic program of fuel substitution, which is now facing severe problems due to the fall of petroleum prices. This study analyzes the recent energy import substitution program in Brazil, specifically concentrating on microeconomic and environmental aspects of fuel substitution.

  13. Morphological divergence in a continental adaptive radiation: South American ovenbirds of the genus Cinclodes

    USGS Publications Warehouse

    Rader, Jonathan A.; Dillon, Michael E.; Chesser, Terry; Sabat, Pablo; Martinez del Rio, Carlos

    2015-01-01

    Cinclodes is an ecologically diverse genus of South American passerine birds and represents a case of continental adaptive radiation along multiple axes. We investigated morphological diversification in Cinclodes using a comprehensive set of morphometric measurements of study skins. Principal component analysis identified 2 primary axes of morphological variation: one describing body size and a second capturing differences in wing-tip shape and toe length. Phylogenetic analyses of the first principal component suggest an early divergence ofCinclodes into 2 main clades characterized by large and small body sizes. We suggest that 2 morphological outliers within these main clades (C. antarcticus and C. palliatus) may be cases of island gigantism and that a third (C. patagonicus) may reflect ecological character displacement. Despite its ecological and physiological diversity, the genus Cinclodes does not appear to show morphological diversity beyond what is typical of other avian genera.

  14. Calcium Imaging in Pluripotent Stem Cell-Derived Cardiac Myocytes.

    PubMed

    Walter, Anna; Šari?, Tomo; Hescheler, Jürgen; Papadopoulos, Symeon

    2016-01-01

    The possibility to generate cardiomyocytes (CMs) from disease-specific induced pluripotent stem cells (iPSCs) is a powerful tool for the investigation of various cardiac diseases in vitro. The pathological course of various cardiac conditions, causatively heterogeneous, often converges into disturbed cellular Ca(2+) cycling. The gigantic Ca(2+) channel of the intracellular Ca(2+) store of CMs, the ryanodine receptor type 2 (RyR2), controls Ca(2+) release and therefore plays a crucial role in Ca(2+) cycling of CMs. In the present protocol we describe ways to measure and analyze global as well as local cellular Ca(2+) release events in CMs derived from a patient carrying a CPVT-causing RyR2 mutation. PMID:26025623

  15. Ancient DNA reveals elephant birds and kiwi are sister taxa and clarifies ratite bird evolution.

    PubMed

    Mitchell, Kieren J; Llamas, Bastien; Soubrier, Julien; Rawlence, Nicolas J; Worthy, Trevor H; Wood, Jamie; Lee, Michael S Y; Cooper, Alan

    2014-05-23

    The evolution of the ratite birds has been widely attributed to vicariant speciation, driven by the Cretaceous breakup of the supercontinent Gondwana. The early isolation of Africa and Madagascar implies that the ostrich and extinct Madagascan elephant birds (Aepyornithidae) should be the oldest ratite lineages. We sequenced the mitochondrial genomes of two elephant birds and performed phylogenetic analyses, which revealed that these birds are the closest relatives of the New Zealand kiwi and are distant from the basal ratite lineage of ostriches. This unexpected result strongly contradicts continental vicariance and instead supports flighted dispersal in all major ratite lineages. We suggest that convergence toward gigantism and flightlessness was facilitated by early Tertiary expansion into the diurnal herbivory niche after the extinction of the dinosaurs. PMID:24855267

  16. Mechanism of enhanced optical second-harmonic generation in the conducting pyrochlore-type Pb2Ir2O7-x oxide compound.

    PubMed

    Hirata, Yasuyuki; Nakajima, Makoto; Nomura, Yusuke; Tajima, Hiroyuki; Matsushita, Yoshitaka; Asoh, Keiko; Kiuchi, Yoko; Eguiluz, Adolfo G; Arita, Ryotaro; Suemoto, Tohru; Ohgushi, Kenya

    2013-05-01

    The structural, electronic, and optical properties of pyrochlore-type Pb(2)Ir(2)O(6)O(0.55)('), which is a metal without spatial inversion symmetry at room temperature, were investigated. Structural analysis revealed that the structural distortion relevant to the breakdown of the inversion symmetry is dominated by the Pb-O' network but is very small in the Ir-O network. At the same time, gigantic second-harmonic generation signals were observed, which can only occur if the local environment of the Ir 5d electrons features broken inversion symmetry. First-principles electronic structure calculations reveal that the underlying mechanism for this phenomenon is the induction of the noncentrosymmetricity in the Ir 5d bands by the strong hybridization with O' 2p orbitals. Our results stimulate theoretical study of inversion-broken iridates, where exotic quantum states such as a topological insulator and Dirac semimetal are anticipated. PMID:23683242

  17. Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation.

    PubMed

    Lawrence, Sara L; Feil, Susanne C; Morton, Craig J; Farrand, Allison J; Mulhern, Terrence D; Gorman, Michael A; Wade, Kristin R; Tweten, Rodney K; Parker, Michael W

    2015-01-01

    Pore-forming proteins are weapons often used by bacterial pathogens to breach the membrane barrier of target cells. Despite their critical role in infection important structural aspects of the mechanism of how these proteins assemble into pores remain unknown. Streptococcus pneumoniae is the world's leading cause of pneumonia, meningitis, bacteremia and otitis media. Pneumolysin (PLY) is a major virulence factor of S. pneumoniae and a target for both small molecule drug development and vaccines. PLY is a member of the cholesterol-dependent cytolysins (CDCs), a family of pore-forming toxins that form gigantic pores in cell membranes. Here we present the structure of PLY determined by X-ray crystallography and, in solution, by small-angle X-ray scattering. The crystal structure reveals PLY assembles as a linear oligomer that provides key structural insights into the poorly understood early monomer-monomer interactions of CDCs at the membrane surface. PMID:26403197

  18. Chandra X-Ray Observatory Image of Cassiopeia A

    NASA Technical Reports Server (NTRS)

    1999-01-01

    This is an extraordinary first image from the Chandra X-Ray Observatory (CXO), the supernova remnant Cassiopeia A, tracing the aftermath of a gigantic stellar explosion in such sturning detail that scientists can see evidence of what may be a neutron star or black hole near the center. The red, green, and blue regions in this image of the supernova remnant Cassiopeia A show where the intensity of low, medium, and high energy X-rays, respectively, is greatest. The red material on the left outer edge is enriched in iron, whereas the bright greenish white region on the low left is enriched in silicon and sulfur. In the blue region on the right edge, low and medium energy X-rays have been filtered out by a cloud of dust and gas in the remnant . The image was made with the CXO's Advanced Charged-Coupled Device (CCD) Imaging Spectrometer (ACIS). Photo credit: NASA/CXC/SAO/Rutgers/J.Hughes

  19. Fates of the most massive primordial stars

    NASA Astrophysics Data System (ADS)

    Chen, Ke-Jung; Heger, Alexander; Almgren, Ann; Woosley, Stan

    2012-09-01

    We present our results of numerical simulations of the most massive primordial stars. For the extremely massive non-rotating Pop III stars over 300Msolar, they would simply die as black holes. But the Pop III stars with initial masses 140 - 260Msolar may have died as gigantic explosions called pair-instability supernovae (PSNe). We use a new radiation-hydrodynamics code CASTRO to study evolution of PSNe. Our models follow the entire explosive burning and the explosion until the shock breaks out from the stellar surface. In our simulations, we find that fluid instabilities occurred during the explosion. These instabilities are driven by both nuclear burning and hydrodynamical instability. In the red supergiant models, fluid instabilities can lead to significant mixing of supernova ejecta and alter the observational signature.

  20. Impact of Parallel Computing on Large Scale Aeroelastic Computations

    NASA Technical Reports Server (NTRS)

    Guruswamy, Guru P.; Kwak, Dochan (Technical Monitor)

    2000-01-01

    Aeroelasticity is computationally one of the most intensive fields in aerospace engineering. Though over the last three decades the computational speed of supercomputers have substantially increased, they are still inadequate for large scale aeroelastic computations using high fidelity flow and structural equations. In addition to reaching a saturation in computational speed because of changes in economics, computer manufactures are stopping the manufacturing of mainframe type supercomputers. This has led computational aeroelasticians to face the gigantic task of finding alternate approaches for fulfilling their needs. The alternate path to over come speed and availability limitations of mainframe type supercomputers is to use parallel computers. During this decade several different architectures have evolved. In FY92 the US Government started the High Performance Computing and Communication (HPCC) program. As a participant in this program NASA developed several parallel computational tools for aeroelastic applications. This talk describes the impact of those application tools on high fidelity based multidisciplinary analysis.

  1. Imaging features of macrodystrophia lipomatosa: an unusual cause of a brawny arm.

    PubMed

    Dhanasekaran, Jagadeesan; Reddy, Ajit Kumar; Sarawagi, Radha; Lakshmanan, Prakash Manikka

    2014-01-01

    Macrodystrophia lipomatosa (MDL), a rare non-hereditary congenital disorder of localised gigantism, is characterised by progressive proliferation of all mesenchymal elements, with a disproportionate increase in fibroadipose tissue. We report a case of a 19-year-old man who presented with a history of painless enlargement of the left upper limb since childhood, which was gradually increasing in size and predominantly involving the radial aspect of the upper limb with relative sparing of the ulnar aspect. The patient was imaged with X-ray and MRI. Imaging and clinical features were classical of MDL. The patient underwent stage 1 reduction plasty of the left forearm; preoperative and histopathological findings confirmed the preoperative diagnosis. PMID:25406225

  2. A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout mice.

    PubMed

    Acs, Peter; Bauer, Peter O; Mayer, Balazs; Bera, Tapan; Macallister, Rhonda; Mezey, Eva; Pastan, Ira

    2015-05-01

    Human ciliopathies are genetic disorders caused by mutations in genes responsible for the formation and function of primary cilia. Some are associated with hyperphagia and obesity (e.g., Bardet-Biedl Syndrome, Alström Syndrome), but the mechanisms underlying these problems are not fully understood. The human gene ANKRD26 is located on 10p12, a locus that is associated with some forms of hereditary obesity. Previously, we reported that disruption of this gene causes hyperphagia, obesity and gigantism in mice. In the present study, we looked for the mechanisms that induce hyperphagia in the Ankrd26-/- mice and found defects in primary cilia in regions of the central nervous system that control appetite and energy homeostasis. PMID:24633808

  3. Macrodystrophia lipomatosa of foot involving great toe.

    PubMed

    Gaur, A K; Mhambre, A S; Popalwar, H; Sharma, R

    2014-06-01

    Macrodystrophia lipomatosa is a rare form of congenital disorder in which there is localized gigantism characterized by progressive overgrowth of all mesenchymal elements with a disproportionate increase in the fibroadipose tissues. The adipose tissue infiltration involves subcutaneous tissue, periosteum, nerves and bone marrow. Most of the cases reported have hand or foot involvement. Patient seeks medical help for improving cosmesis or to get the size of the involved part reduced in order to reduce mechanical problems. We report a case of macrodystrophia lipomatosa involving medial side of foot with significant enlargement of great toe causing concern for cosmesis and inconvenience due to mechanical problems. The X-rays showed increased soft tissue with more of adipose tissue and increased size of involved digits with widening of ends. Since the patient's mother did not want any surgical intervention he was educated about foot care and proper footwear design was suggested. PMID:24703060

  4. Pituitary adenomas in childhood and adolescence.

    PubMed

    Jackman, Suzanne; Diamond, Frank

    2013-07-01

    Scientific advances are revealing the complexity of pituitary development, which is controlled by multiple transcription factors and signaling molecules. Unregulated pituitary cell growth, resulting in pituitary adenoma, is usually sporadic and results from monoclonal expansion of a single mutated cell. However, some adenomas develop as part of a genetic syndrome. Prolactinoma is the most common hormonally active pituitary adenoma in children. The non-functioning (non-secreting) pituitary adenoma is the second most common and often stains positive for GH, PRL, and/or TSH. While Cushing disease, resulting from an ACTH-secreting adenoma, commonly manifests as weight gain with growth deceleration in children, GH excess causes gigantism with rapid, accelerated growth inappropriate for the height of the family. TSH secreting pituitary adenomas are rare, and biochemical analysis will show an elevated thyroxine level with a non-suppressed or high TSH. Though the natural history of pituitary incidentalomas in children is unknown, adult practice guidelines are established. PMID:23957196

  5. Evaluation of geometrical contributions to the spread of the Compton-scatter energy distribution

    NASA Astrophysics Data System (ADS)

    Hanson, A. L.; Gigante, G. E.

    1989-07-01

    The spectrum from Compton-scattered x rays is an inherently broad distribution. This distribution is the sum of several Gaussian-like distributions, which gives the sum its unique shape. The Gaussian-like distributions are the result of convoluting the so-called Compton profile, the spread in the scattered-x-ray energies due to the momentum distributions of the target electrons, with the detector response and the geometrical effects. The distribution is then further modified by the absorption within the sample. A formulation for both qualitatively and quantitatively determining the magnitude of the geometrical contributions is presented. This formulation is based on a recently devised approach to the scattering geometry [Hanson, Gigante, Meron, Phys. Rev. Lett. 61, 135 (1988)]. A methodology for determining the geometrical spread in the energy of the scattered x rays is presented. The results can be conveniently used to optimize scattering geometries for the reduction of the geometry-caused spread.

  6. The skull of the giant predatory pliosaur Rhomaleosaurus cramptoni: implications for plesiosaur phylogenetics

    NASA Astrophysics Data System (ADS)

    Smith, Adam S.; Dyke, Gareth J.

    2008-10-01

    The predatory pliosaurs were among the largest creatures ever to inhabit the oceans, some reaching gigantic proportions greater than 15 m in length. Fossils of this subclade of plesiosaurs are known from sediments all over the world, ranging in age from the Hettangian (approximately 198 Myr) to the Turonian (approximately 92 Myr). However, due to a lack of detailed studies and because only incomplete specimens are usually reported, pliosaur evolution remains poorly understood. In this paper, we describe the three dimensionally preserved skull of the giant Jurassic pliosaur Rhomaleosaurus cramptoni. The first phylogenetic analysis dedicated to in-group relationships of pliosaurs allows us to hypothesise a number of well-supported lineages that correlate with marine biogeography and the palaeoecology of these reptiles. Rhomaleosaurids comprised a short-lived and early diverging lineage within pliosaurs, whose open-water top-predator niche was filled by other pliosaur taxa by the mid-late Jurassic.

  7. Fraud in the acid rain debate

    SciTech Connect

    Bagge, C.

    1984-06-01

    Electric utility executives, according to the author, and millions of other Americans are the victims of a gigantic fraud being carried on in the name of controlling acid rain. This fraud, states the author, involves the distorted, dire image of acidity in nature being created by environmental groups, politicians and others - to gain public sympathy for their legislative goals. The alleged fraud involves the very nature of the legislation being promoted as a low-cost cure for acid rain. On the basis of scientific evidence to date there is no assurance it will reduce acidity by any appreciable amount, but on the other hand it most certainly will cost users of electricity hundreds of billions of dollars in new costs. What has already happened to the nuclear industry is also meant for coal.

  8. Magnetic biasing of a ferroelectric hysteresis loop in a multiferroic orthoferrite.

    PubMed

    Tokunaga, Y; Taguchi, Y; Arima, T; Tokura, Y

    2014-01-24

    In a multiferroic orthoferrite Dy0.7Tb0.3FeO3, which shows electric-field-(E-)driven magnetization (M) reversal due to a tight clamping between polarization (P) and M, a gigantic effect of magnetic-field (H) biasing on P-E hysteresis loops is observed in the case of rapid E sweeping. The magnitude of the bias E field can be controlled by varying the magnitude of H, and its sign can be reversed by changing the sign of H or the relative clamping direction between P and M. The origin of this unconventional biasing effect is ascribed to the difference in the Zeeman energy between the +P and -P states coupled with the M states with opposite sign. PMID:24484164

  9. Lead in ancient Rome’s city waters

    PubMed Central

    Delile, Hugo; Blichert-Toft, Janne; Goiran, Jean-Philippe; Keay, Simon; Albarède, Francis

    2014-01-01

    It is now universally accepted that utilization of lead for domestic purposes and water distribution presents a major health hazard. The ancient Roman world was unaware of these risks. How far the gigantic network of lead pipes used in ancient Rome compromised public health in the city is unknown. Lead isotopes in sediments from the harbor of Imperial Rome register the presence of a strong anthropogenic component during the beginning of the Common Era and the Early Middle Ages. They demonstrate that the lead pipes of the water distribution system increased Pb contents in drinking water of the capital city by up to two orders of magnitude over the natural background. The Pb isotope record shows that the discontinuities in the pollution of the Tiber by lead are intimately entwined with the major issues affecting Late Antique Rome and its water distribution system. PMID:24753588

  10. Lead in ancient Rome's city waters.

    PubMed

    Delile, Hugo; Blichert-Toft, Janne; Goiran, Jean-Philippe; Keay, Simon; Albarède, Francis

    2014-05-01

    It is now universally accepted that utilization of lead for domestic purposes and water distribution presents a major health hazard. The ancient Roman world was unaware of these risks. How far the gigantic network of lead pipes used in ancient Rome compromised public health in the city is unknown. Lead isotopes in sediments from the harbor of Imperial Rome register the presence of a strong anthropogenic component during the beginning of the Common Era and the Early Middle Ages. They demonstrate that the lead pipes of the water distribution system increased Pb contents in drinking water of the capital city by up to two orders of magnitude over the natural background. The Pb isotope record shows that the discontinuities in the pollution of the Tiber by lead are intimately entwined with the major issues affecting Late Antique Rome and its water distribution system. PMID:24753588

  11. The supergiant amphipod Alicella gigantea (Crustacea: Alicellidae) from hadal depths in the Kermadec Trench, SW Pacific Ocean

    NASA Astrophysics Data System (ADS)

    Jamieson, A. J.; Lacey, N. C.; Lörz, A.-N.; Rowden, A. A.; Piertney, S. B.

    2013-08-01

    Here we provide the first record of the 'supergiant' amphipod Alicella gigantea Chevreux, 1899 (Alicellidae) from the Southern Hemisphere, and extend the known bathymetric range by over 1000 m to 7000 m. An estimated nine individuals were observed across 1500 photographs taken in situ by baited camera at 6979 m in the Kermadec Trench, SW Pacific Ocean. Nine specimens, ranging in length from 102 to 290 mm were recovered by baited trap at depths of 6265 m and 7000 m. Mitochondrial and nuclear DNA sequences obtained indicate a cosmopolitan distribution for the species. Data and observations from the study are used to discuss the reason for gigantism in this species, and its apparently disjunct geographical distribution.

  12. Dynamics of the Earth's Inner Magnetosphere and its Connection to the Ionosphere: Current Understanding and Challenges

    NASA Technical Reports Server (NTRS)

    Zheng, Yihua

    2010-01-01

    The Earth's inner magnetosphere, a vast volume in space spanning from 1.5 Re (Earth radii) to 10 Re, is a host to a variety of plasma populations (with energy from 1 eV to few MeV) and physical processes where most of which involve plasma and field coupling. As a gigantic particle accelerator, the inner magnetosphere includes three overlapping regions: the plasmasphere, the ring current, and the Van Allen radiation belt. The complex structures and dynamics of these regions are externally driven by solar activities and internally modulated by intricate interactions and coupling. As a major constituent of Space Weather, the inner magnetosphere is both scientifically intriguing and practically important to our society. In this presentation, I will discuss our recent results from the Comprehensive Ring Current Model, in the context of our current understanding of the inner magnetosphere in general and challenges ahead in making further progresses.

  13. Dynamics of the Earth's Inner Magnetosphere and Its Connection to the Ionosphere: Current Understanding and Challenges

    NASA Technical Reports Server (NTRS)

    Zheng, Yihua

    2011-01-01

    The Earth's inner magnetosphere, a vast volume in space spanning from 1.5 Re (Earth radii) to 10 Re, is a host to a variety of plasma populations (with energy from 1 eV to few MeV) and physical processes where most of which involve plasma and field coupling. As a gigantic particle accelerator, the inner magnetosphere includes three overlapping regions: the plasmasphere, the ring current, and the Van Allen radiation belt. The complex structures and dynamics of these regions are externally driven by solar activities and internally modulated by intricate interactions and coupling. As a major constituent of Space Weather, the inner magnetosphere is both scientifically intriguing and practically important to our society. In this presentation, I will discuss our recent results from the Comprehensive Ring Current Model, in the context of our current understanding of the inner magnetosphere in general and challenges ahead in making further progresses.

  14. Surgical Treatment of an Immature Short-Rooted Traumatized Incisor with an Extensive Apical Lesion Using CEM Cement

    PubMed Central

    Asgary, Saeed; Fazlyab, Mahta

    2015-01-01

    Severe traumatic injuries to immature teeth often cause damage to periodontal ligament as well as dental pulp; pulp necrosis, root resorption and subsequent apical lesion are common consequences. This article reports the surgical management of an infected immature maxillary central incisor associated with a gigantic periradicular lesion and severe root resorption. The tooth had a history of trauma and the patient suffered from purulent sinus tract and tooth mobility. After unsuccessful multi-session disinfection with calcium hydroxide, root end surgery was planned. During flap surgery and lesion enucleation, the root end was cleaned and filled with calcium-enriched mixture (CEM) cement. After one year, the radiographic examination revealed that the lesion was almost completely replaced with newly formed bone. In addition, clinical examination showed favorable outcomes; the tooth was symptom-free and in function. Due to chemical, physical and biological properties of CEM cement, this biomaterial might be considered as the root-end filling material of choice. PMID:25834603

  15. The potassium-argon age of the Kara craters and their relation to the Cretaceous-Paleogene impact event

    NASA Astrophysics Data System (ADS)

    Kolesnikov, E. M.; Nazarov, M. A.; Badiukov, D. D.; Korina, M. I.; Smoliar, M. I.

    1990-04-01

    Results are presented of the potassium-argon dating of glass and rock samples from the Kara and the Us't'-Kara craters (believed to be connected with the catastrophic collision of the earth with a gigantic meteorite, believed by some to have caused a major biological catastrophe in the late Mesozoic period), showing that the ages obtained depend upon the structure of samples and, thus, can be inaccurate. No difference was found for the times of origin estimated for the Kara and the Us't'-Kara craters. Their isochrone age is about 66.1 + or - 0.8 years, corresponding to the present estimates of the boundary between the Cretaceous and Paleogene periods.

  16. Millimeter Radio Astronomy and the Solar Convection Zone

    NASA Astrophysics Data System (ADS)

    Arkhypov, O. V.; Antonov, O. V.; Khodachenko, M. L.

    The global distribution of solar surface activity (active regions) is connected with processes in the convection zone. To extract the information on large-scale motions in the convection zone, we study the solar synoptic charts (Mount Wilson 1998-2004, Fe I, 525.02 nm). The clear indication of large-scale ( ? 18 degree) turbulence is found. This may be a manifestations of the deep convection because there is no such global turbulent eddies in the solar photosphere. The preferred scales of longitudinal variations in surface solar activity are revealed. These correspond to about 15 degree to 51 degree (gigantic convection cells), 90 degree, 180 degree and 360 degree. Similar scales (e.g., 40 degree and 90 degree) are found in the millimeter radio-images (Metsahovi Radio Observatory 1994-1998, 37 and 87 GHz). Hence, the millimeter radio astronomy could prove useful for remote sensing of the solar convection zone.

  17. Ancient drainage basin of the Tharsis region, Mars: Potential source for outflow channel systems and putative oceans or paleolakes

    USGS Publications Warehouse

    Dohm, J.M.; Ferris, J.C.; Baker, V.R.; Anderson, R.C.; Hare, T.M.; Strom, R.G.; Barlow, N.G.; Tanaka, K.L.; Klemaszewski, J.E.; Scott, D.H.

    2001-01-01

    Paleotopographic reconstructions based on a synthesis of published geologic information and high-resolution topography, including topographic profiles, reveal the potential existence of an enormous drainage basin/aquifer system in the eastern part of the Tharsis region during the Noachian Period. Large topographic highs formed the margin of the gigantic drainage basin. Subsequently, lavas, sediments, and volatiles partly infilled the basin, resulting in an enormous and productive regional aquifer. The stacked sequences of water-bearing strata were then deformed locally and, in places, exposed by magmatic-driven uplifts, tectonic deformation, and erosion. This basin model provides a potential source of water necessary to carve the large outflow channel systems of the Tharsis and surrounding regions and to contribute to the formation of putative northern-plains ocean(s) and/or paleolakes. Copyright 2001 by the American Geophysical Union.

  18. The intersection of urban planning, art, and public health: the Sunnyside Piazza.

    PubMed

    Semenza, Jan C

    2003-09-01

    Deteriorating physical features of urban environments can negatively influence public health. Dilapidated environments and urban blight tend to promote alienation and can be associated with social disorder, vandalism, crime, drug abuse, traffic violations, and littering, which in turn affects health and well-being. In the late 1990s, the Sunnyside neighborhood in Portland, Ore, was plagued by many of these problems. In an attempt to invigorate neighborhood stewardship, the community organized and created a public gathering place; together, they painted a gigantic sunflower in the middle of an intersection and installed several interactive art features. As a result of these collective actions of "place-making," social capital has increased, thus revitalizing the community, and expanded social networks among residents have stimulated a sense of well-being. PMID:12948959

  19. The Intersection of Urban Planning, Art, and Public Health: The Sunnyside Piazza

    PubMed Central

    Semenza, Jan C.

    2003-01-01

    Deteriorating physical features of urban environments can negatively influence public health. Dilapidated environments and urban blight tend to promote alienation and can be associated with social disorder, vandalism, crime, drug abuse, traffic violations, and littering, which in turn affects health and well-being. In the late 1990s, the Sunnyside neighborhood in Portland, Ore, was plagued by many of these problems. In an attempt to invigorate neighborhood stewardship, the community organized and created a public gathering place; together, they painted a gigantic sunflower in the middle of an intersection and installed several interactive art features. As a result of these collective actions of “place-making,” social capital has increased, thus revitalizing the community, and expanded social networks among residents have stimulated a sense of well-being. PMID:12948959

  20. Lightning and middle atmospheric discharges in the atmosphere

    NASA Astrophysics Data System (ADS)

    Siingh, Devendraa; Singh, R. P.; Kumar, Sarvan; Dharmaraj, T.; Singh, Abhay K.; Singh, Ashok K.; Patil, M. N.; Singh, Shubha

    2015-11-01

    Recent development in lightning discharges including transient luminous events (TLEs) and global electric circuit are discussed. Role of solar activity, convective available potential energy, surface temperature and difference of land-ocean surfaces on convection process are discussed. Different processes of discharge initiation are discussed. Events like sprites and halos are caused by the upward quasi-electrostatic fields associated with intense cloud-to-ground discharges while jets (blue starter, blue jet, gigantic jet) are caused by charge imbalance in thunderstorm during lightning discharges but they are not associated with a particular discharge flash. Elves are generated by the electromagnetic pulse radiated during lightning discharges. The present understanding of global electric circuit is also reviewed. Relation between lightning activity/global electric circuit and climate is discussed.

  1. Groundwater formation of martian valleys

    USGS Publications Warehouse

    Malin, M.C.; Carr, M.H.

    1999-01-01

    The martian surface shows large outflow channels, widely accepted as having been formed by gigantic floods that could have occurred under climatic conditions like those seen today. Also present are branching valley networks that commonly have tributaries. These valleys are much smaller than the outflow channels and their origins and ages have been controversial. For example, they might have formed through slow erosion by water running across the surface, either early or late in Mars' history, possibly protected from harsh conditions by ice cover. Alternatively, they might have formed through groundwater or ground-ice processes that undermine the surface and cause collapse, again either early or late in Mars' history. Long-duration surface runoff would imply climatic conditions quite different from the present environment. Here we present high-resolution images of martian valleys that support the view that ground water played an important role in their formation, although we are unable as yet to establish when this occurred.

  2. Quantum renormalization of the spin Hall effect.

    PubMed

    Gu, Bo; Gan, Jing-Yu; Bulut, Nejat; Ziman, Timothy; Guo, Guang-Yu; Nagaosa, Naoto; Maekawa, Sadamichi

    2010-08-20

    By quantum Monte Carlo simulation of a realistic multiorbital Anderson impurity model, we study the spin-orbit interaction (SOI) of an Fe impurity in Au host metal. We show, for the first time, that the SOI is strongly renormalized by the quantum spin fluctuation. Based on this mechanism, we can explain why the gigantic spin Hall effect in Au with Fe impurities was observed in recent experiments, while it is not visible in the anomalous Hall effect. In addition, we show that the SOI is strongly renormalized by the Coulomb correlation U. Based on this picture, we can explain past discrepancies in the calculated orbital angular momenta for an Fe impurity in an Au host. PMID:20868117

  3. Visualizing a Complete Siphoviridae Member by Single-Particle Electron Microscopy: the Structure of Lactococcal Phage TP901-1

    PubMed Central

    Bebeacua, Cecilia; Lai, Livia; Vegge, Christina Skovgaard; Brøndsted, Lone; van Heel, Marin

    2013-01-01

    Tailed phages are genome delivery machines exhibiting unequaled efficiency acquired over more than 3 billion years of evolution. Siphophages from the P335 and 936 families infect the Gram-positive bacterium Lactococcus lactis using receptor-binding proteins anchored to the host adsorption apparatus (baseplate). Crystallographic and electron microscopy (EM) studies have shed light on the distinct adsorption strategies used by phages of these two families, suggesting that they might also rely on different infection mechanisms. Here, we report electron microscopy reconstructions of the whole phage TP901-1 (P335 species) and propose a composite EM model of this gigantic molecular machine. Our results suggest conservation of structural proteins among tailed phages and add to the growing body of evidence pointing to a common evolutionary origin for these virions. Finally, we propose that host adsorption apparatus architectures have evolved in correlation with the nature of the receptors used during infection. PMID:23135714

  4. On the fate of pumice rafts formed during the 2012 Havre submarine eruption.

    PubMed

    Jutzeler, Martin; Marsh, Robert; Carey, Rebecca J; White, James D L; Talling, Peter J; Karlstrom, Leif

    2014-01-01

    Pumice rafts are floating mobile accumulations of low-density pumice clasts generated by silicic volcanic eruptions. Pumice in rafts can drift for years, become waterlogged and sink, or become stranded on shorelines. Here we show that the pumice raft formed by the impressive, deep submarine eruption of the Havre caldera volcano (Southwest Pacific) in July 2012 can be mapped by satellite imagery augmented by sailing crew observations. Far from coastal interference, the eruption produced a single >400 km(2) raft in 1 day, thus initiating a gigantic, high-precision, natural experiment relevant to both modern and prehistoric oceanic surface dispersal dynamics. Observed raft dispersal can be accurately reproduced by simulating drift and dispersal patterns using currents from an eddy-resolving ocean model hindcast. For future eruptions that produce potentially hazardous pumice rafts, our technique allows real-time forecasts of dispersal routes, in addition to inference of ash/pumice deposit distribution in the deep ocean. PMID:24755668

  5. Armageddon, oil, and the Middle East crisis

    SciTech Connect

    Walvoord, J.F.; Walvoord, J.E.

    1980-01-01

    This book relates the intricate subject of biblical prophecy to the current crisis in the Middle East. With the development of oil politics, Dr. Walvoord believes a new world government will emerge, centered in the Middle East, which will eclipse the United States and Russia as world powers. The world government will be subjected to catastrophic, divine judgments which precipitate a gigantic world war culminating in Armageddon. Each chapter is devoted to the scriptural explanations of events leading to the second coming of Christ. The result is a prophetic calendar summing up to the countdown to Armageddon. Some of the chapter titles include: the Arab oil blackmail; watch Jerusalen; the rising tide of world religion; the coming Middle East peace; the coming world dictator; and Armageddon: the world's death struggle.

  6. A Graph Summarization Algorithm Based on RFID Logistics

    NASA Astrophysics Data System (ADS)

    Sun, Yan; Hu, Kongfa; Lu, Zhipeng; Zhao, Li; Chen, Ling

    Radio Frequency Identification (RFID) applications are set to play an essential role in object tracking and supply chain management systems. The volume of data generated by a typical RFID application will be enormous as each item will generate a complete history of all the individual locations that it occupied at every point in time. The movement trails of such RFID data form gigantic commodity flowgraph representing the locations and durations of the path stages traversed by each item. In this paper, we use graph to construct a warehouse of RFID commodity flows, and introduce a database-style operation to summarize graphs, which produces a summary graph by grouping nodes based on user-selected node attributes, further allows users to control the hierarchy of summaries. It can cut down the size of graphs, and provide convenience for users to study just on the shrunk graph which they interested. Through extensive experiments, we demonstrate the effectiveness and efficiency of the proposed method.

  7. Molecular Donor-Acceptor Compounds as Prospective Organic Electronics Materials

    NASA Astrophysics Data System (ADS)

    Horiuchi, Sachio; Hasegawa, Tatsuo; Tokura, Yoshinori

    2006-05-01

    The ?-electronic functionalities of molecular donor (D)-acceptor (A) compounds have been attracting subjects for the solid state science as well as for the prospective technological exploitation in organic electronics. In this review, it is shown that the novel neutral-ionic valence instability in the charge-transfer (CT) complexes is closely related to valuable electric properties such as the current-induced resistance switching, quantum phase transition, gigantic dielectric response, and relaxor ferroelectricity. Furthermore, the displacive-type ferroelectricity has recently been developed on the DA combinations in the hydrogen-bonded co-crystals. It is also discussed that the intermolecular CT mechanism in the molecular DA compounds is promising to advance the potential of organic field-effect transistors (FETs) that are envisioned as key components in future organic electronics.

  8. [Relationship between disaster stress and peptic ulcers].

    PubMed

    Kanno, Takeshi; Iijima, Katsunori; Koike, Tomoyuki; Shimosegawa, Tooru

    2015-07-01

    There had been several reports about the increasing of peptic ulcers under a large-scale disaster or a war. But in human, it was still unclear that a severe psychological stress itself cause peptic ulcer independently of two major causes (Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs). After Great East Japan earthquake in March 11th, 2011, one of the five most powerful earthquakes in the world since modern record keeping began in 1900, we also noticed remarkable increasing of patients with peptic ulcer in wide stricken area. Reports after this gigantic earthquake gave us two new important viewpoints. Disaster (psychological) stress possibly induce peptic ulcer independently of two major causes. And, people living in refugee shelter immediately after a disaster are strong risk group of peptic ulcer bleeding as well as an intake of anti-thrombotic agents. PMID:26165082

  9. 6Li-loaded directionally sensitive anti-neutrino detector for possible geo-neutrinographic imaging applications

    PubMed Central

    Tanaka, H. K. M.; Watanabe, H.

    2014-01-01

    Despite the latent and unique benefits of imaging uranium and thorium's distribution in the earth's interior, previously proposed experimental techniques used to identify the incoming geo-neutrino's direction are not applicable to practical imaging due to the high miss-identification in a neutrino's track reconstruction. After performing experimental studies and Monte-Carlo simulations, we confirmed that a significant improvement is possible in neutrino tracking identification with a 6Li-loaded neutrino detector. For possible imaging applications, we also explore the feasibility of producing geo-neutrinographic images of gigantic magmatic reservoirs and deep structure in the mantle. We anticipate and plan to apply these newly designed detectors to radiographic imaging of the Earth's interior, monitoring of nuclear reactors, and tracking astrophysical sources of neutrinos. PMID:24759616

  10. Wigner Crystal and Colossal Magnetoresistance in InSb Doped with Mn

    PubMed Central

    Obukhov, S. A.; Tozer, S. W.; Coniglio, W. A.

    2015-01-01

    We report magnetotransport investigation of nonmagnetic InSb single crystal doped with manganese at Mn concentration NMn?~?1,5?×?1017?cm?3 in the temperature range T?=?300?K–40?mK, magnetic field B?=?0–25T and hydrostatic pressure P?=?0–17?kbar. Resistivity saturation was observed in the absence of magnetic field at temperatures below 200?mK while applied increasing external magnetic field induced colossal drop of resistivity (by factor 104) at B?~?4T with further gigantic resistivity increase (by factor 104) at 15T. Under pressure, P?=?17?kbar, resistivity saturation temperature increased up to 1,2?K. Existing models are discussed in attempt to explain resistivity saturation, dramatic influence of magnetic field and pressure on resistivity with the focus on possible manifestation of three dimensional Wigner crystal formed in InSb by light electrons and heavy holes. PMID:26307952

  11. ?Li-loaded directionally sensitive anti-neutrino detector for possible geo-neutrinographic imaging applications.

    PubMed

    Tanaka, H K M; Watanabe, H

    2014-01-01

    Despite the latent and unique benefits of imaging uranium and thorium's distribution in the earth's interior, previously proposed experimental techniques used to identify the incoming geo-neutrino's direction are not applicable to practical imaging due to the high miss-identification in a neutrino's track reconstruction. After performing experimental studies and Monte-Carlo simulations, we confirmed that a significant improvement is possible in neutrino tracking identification with a (6)Li-loaded neutrino detector. For possible imaging applications, we also explore the feasibility of producing geo-neutrinographic images of gigantic magmatic reservoirs and deep structure in the mantle. We anticipate and plan to apply these newly designed detectors to radiographic imaging of the Earth's interior, monitoring of nuclear reactors, and tracking astrophysical sources of neutrinos. PMID:24759616

  12. Is IGSF1 involved in human pituitary tumor formation?

    PubMed

    Faucz, Fabio R; Horvath, Anelia D; Azevedo, Monalisa F; Levy, Isaac; Bak, Beata; Wang, Ying; Xekouki, Paraskevi; Szarek, Eva; Gourgari, Evgenia; Manning, Allison D; de Alexandre, Rodrigo Bertollo; Saloustros, Emmanouil; Trivellin, Giampaolo; Lodish, Maya; Hofman, Paul; Anderson, Yvonne C; Holdaway, Ian; Oldfield, Edward; Chittiboina, Prashant; Nesterova, Maria; Biermasz, Nienke R; Wit, Jan M; Bernard, Daniel J; Stratakis, Constantine A

    2015-02-01

    IGSF1 is a membrane glycoprotein highly expressed in the anterior pituitary. Pathogenic mutations in the IGSF1 gene (on Xq26.2) are associated with X-linked central hypothyroidism and testicular enlargement in males. In this study, we tested the hypothesis that IGSF1 is involved in the development of pituitary tumors, especially those that produce growth hormone (GH). IGSF1 was sequenced in 21 patients with gigantism or acromegaly and 92 healthy individuals. Expression studies with a candidate pathogenic IGSF1 variant were carried out in transfected cells and immunohistochemistry for IGSF1 was performed in the sections of GH-producing adenomas, familial somatomammotroph hyperplasia, and in normal pituitary. We identified the sequence variant p.N604T, which in silico analysis suggested could affect IGSF1 function, in two male patients and one female with somatomammotroph hyperplasia from the same family. Of 60 female controls, two carried the same variant and seven were heterozygous for other variants. Immunohistochemistry showed increased IGSF1 staining in the GH-producing tumor from the patient with the IGSF1 p.N604T variant compared with a GH-producing adenoma from a patient negative for any IGSF1 variants and with normal control pituitary tissue. The IGSF1 gene appears polymorphic in the general population. A potentially pathogenic variant identified in the germline of three patients with gigantism from the same family (segregating with the disease) was also detected in two healthy female controls. Variations in IGSF1 expression in pituitary tissue in patients with or without IGSF1 germline mutations point to the need for further studies of IGSF1 action in pituitary adenoma formation. PMID:25527509

  13. Physical characteristics of TLEs inferred from ISUAL observations (Invited)

    NASA Astrophysics Data System (ADS)

    Kuo, C.; Chen, A. B.; Su, H.; Hsu, R.; Frey, H. U.; Mende, S. B.; Takahashi, Y.; Lee, L.

    2010-12-01

    ISUAL/FORMOSAT-2 is the first satellite mission for the long term survey of upper atmospheric transient luminous phenomena/events (TLEs). The payload consists of three sensor packages including an intensified CCD imager, a six-channel spectrophotometer and a dual-band array photometer. Hence ISUAL experiment could provide information to understand the spatial and the temporal evolutions of TLEs. In this presentation, we will review the important findings of the ISUAL mission in the first five years of operation; mainly on the electric field of sprites streamers [Pasko, 2004; Kuo et al., 2005; Liu et al., 2006; Adachi et al., 2006; Liu et al, 2010; Celestin and Pasko, 2010], the FUV emissions of elves [Mende et al., 2005; Chang et al., 2010], the luminous and electric properties of gigantic jets [Su et al., 2005; Kuo et al., 2009; Chou et al., 2010], and the high-altitude sprite current and the lightning continuing current [Cummer et al, 2006; Adachi et al, 2009]. ISUAL has carried out 762 nm-filtered, 557.7 nm-filtered and 427.8 nm-filtered imager campaigns, besides the regular 1PN2 emission survey. For the 762 nm-filtered imager campaign, a weak but detectable O2 Atmospheric band emission (~1 kR) was predicted based on a plasma chemistry model [Sentman et al., 2008], and the image data may have confirmed the existence of this band emission. While, no significant 557.7 nm emissions were detected from the ISUAL recorded elves. In the 427.8 nm campaign, altitudinal ionization profile of sprites was inferred. The ionization structure of elves and the leader structure of gigantic jets will also be discussed.

  14. Measuring the vertical electrical field above an oceanic convection system using a meteorological sounding balloon

    NASA Astrophysics Data System (ADS)

    Chen, A. B.; Chiu, C.; Lai, S.; Chen, C.; Kuo, C.; Su, H.; Hsu, R.

    2012-12-01

    The vertical electric field above thundercloud plays an important role in the generation and modeling of transient luminous events. For example, Pasko [1995] proposed that the high quasi-static E-field following the positive cloud-to-ground lightning could accelerate and input energy to ambient electrons; as they collide and excite nitrogen and oxygen molecules in upper atmosphere, sprites may be induced. A series of balloon experiments led by Holzworth have investigated the temporal and spatial fluctuations of the electric field and conductivity in the upper atmosphere at different sites [Holzworth 2005, and references in]. But the strength and variation of the vertical electric field above thundercloud, especially oceanic ones, are not well documented so far. A lightweight, low-cost measurement system including an electric field meter and the associated aviation electronics are developed to carry out the in-situ measurement of the vertical electric field and the inter-cloud charge distribution. Our measuring system was first deployed using a meteorological sounding balloon from Taitung, Taiwan in May 2012. The measured electric field below 3km height shows an exponential decay and it is consistent with the expected potential gradient variation between ionosphere and the Earth surface. But the background strength of the measured E-field grows up exponentially and a violent fluctuations is also observed when the balloon flew over a developing oceanic convection cell. The preliminary results from this flight will be reported and discussed. This low-cost electric field meter is developed within one year. In the coming months, more flights will be performed with the aim to measure the rapid variation of the electric field above thundercloud as well as the E-field that may induce transient luminous events. Our ground campaigns show that the occurrence rates of blue and gigantic jet are relatively high in the vicinity of Taiwan. Our experiment can be used to diagnose the dynamics of the E-field associated with blue and gigantic jets.

  15. X-linked acrogigantism syndrome: clinical profile and therapeutic responses.

    PubMed

    Beckers, Albert; Lodish, Maya Beth; Trivellin, Giampaolo; Rostomyan, Liliya; Lee, Misu; Faucz, Fabio R; Yuan, Bo; Choong, Catherine S; Caberg, Jean-Hubert; Verrua, Elisa; Naves, Luciana Ansaneli; Cheetham, Tim D; Young, Jacques; Lysy, Philippe A; Petrossians, Patrick; Cotterill, Andrew; Shah, Nalini Samir; Metzger, Daniel; Castermans, Emilie; Ambrosio, Maria Rosaria; Villa, Chiara; Strebkova, Natalia; Mazerkina, Nadia; Gaillard, Stéphan; Barra, Gustavo Barcelos; Casulari, Luis Augusto; Neggers, Sebastian J; Salvatori, Roberto; Jaffrain-Rea, Marie-Lise; Zacharin, Margaret; Santamaria, Beatriz Lecumberri; Zacharieva, Sabina; Lim, Ee Mun; Mantovani, Giovanna; Zatelli, Maria Chaira; Collins, Michael T; Bonneville, Jean-François; Quezado, Martha; Chittiboina, Prashant; Oldfield, Edward H; Bours, Vincent; Liu, Pengfei; W de Herder, Wouter; Pellegata, Natalia; Lupski, James R; Daly, Adrian F; Stratakis, Constantine A

    2015-06-01

    X-linked acrogigantism (X-LAG) is a new syndrome of pituitary gigantism, caused by microduplications on chromosome Xq26.3, encompassing the gene GPR101, which is highly upregulated in pituitary tumors. We conducted this study to explore the clinical, radiological, and hormonal phenotype and responses to therapy in patients with X-LAG syndrome. The study included 18 patients (13 sporadic) with X-LAG and microduplication of chromosome Xq26.3. All sporadic cases had unique duplications and the inheritance pattern in two families was dominant, with all Xq26.3 duplication carriers being affected. Patients began to grow rapidly as early as 2-3 months of age (median 12 months). At diagnosis (median delay 27 months), patients had a median height and weight standard deviation scores (SDS) of >+3.9 SDS. Apart from the increased overall body size, the children had acromegalic symptoms including acral enlargement and facial coarsening. More than a third of cases had increased appetite. Patients had marked hypersecretion of GH/IGF1 and usually prolactin, due to a pituitary macroadenoma or hyperplasia. Primary neurosurgical control was achieved with extensive anterior pituitary resection, but postoperative hypopituitarism was frequent. Control with somatostatin analogs was not readily achieved despite moderate to high levels of expression of somatostatin receptor subtype-2 in tumor tissue. Postoperative use of adjuvant pegvisomant resulted in control of IGF1 in all five cases where it was employed. X-LAG is a new infant-onset gigantism syndrome that has a severe clinical phenotype leading to challenging disease management. PMID:25712922

  16. Is IGSF1 involved in human pituitary tumor formation?

    PubMed Central

    Faucz, Fabio R.; Horvath, Anelia D.; Azevedo, Monalisa F.; Levy, Isaac; Bak, Beata; Wang, Ying; Xekouki, Paraskevi; Szarek, Eva; Gourgari, Evgenia; Manning, Allison D.; de Alexandre, Rodrigo Bertollo; Saloustros, Emmanouil; Trivellin, Giampaolo; Lodish, Maya; Hofman, Paul; Anderson, Yvonne C; Holdaway, Ian; Oldfield, Edward; Chittiboina, Prashant; Nesterova, Maria; Biermasz, Nienke R.; Wit, Jan M.; Bernard, Daniel J.; Stratakis, Constantine A.

    2014-01-01

    IGSF1 is a membrane glycoprotein highly expressed in the anterior pituitary. Pathogenic mutations in the IGSF1 gene (on Xq26.2) are associated with X-linked central hypothyroidism and testicular enlargement in males. In this study we tested the hypothesis that IGSF1 is involved in the development of pituitary tumors, especially those that produce growth hormone (GH). IGSF1 was sequenced in 21 patients with gigantism or acromegaly and 92 healthy individuals. Expression studies with a candidate pathogenic IGSF1 variant were carried out in transfected cells and immunohistochemistry for IGSF1 was performed in sections from GH-producing adenomas, familial somatomammotroph hyperplasia and in normal pituitary. In two male patients, and in one female, with somatomammotroph hyperplasia from the same family, we identified the sequence variant p.N604T, which in silico analysis suggested could affect IGSF1 function. Of 60 female controls, two carried the same variant, and seven were heterozygous for other variants. Immunohistochemistry showed increase IGSF1 staining in the GH-producing tumor from the patient with the IGSF1 p.N604T variant compared to a GH-producing adenoma from a patient negative for any IGSF1 variants and to normal control pituitary tissue. The IGSF1 gene appears polymorphic in the general population. A potentially pathogenic variant identified in the germline of three patients with gigantism from the same family (segregating with the disease) was also detected in two healthy female controls. Variations in IGSF1 expression in pituitary tissue in patients with or without IGSF1 germline mutations point to the need for further studies of IGSF1 action in pituitary adenoma formation. PMID:25527509

  17. Earliest Example of a Giant Monitor Lizard (Varanus, Varanidae, Squamata)

    PubMed Central

    Conrad, Jack L.; Balcarcel, Ana M.; Mehling, Carl M.

    2012-01-01

    Background Varanidae is a clade of tiny (<20 mm pre-caudal length [PCL]) to giant (>600 mm PCL) lizards first appearing in the Cretaceous. True monitor lizards (Varanus) are known from diagnostic remains beginning in the early Miocene (Varanus rusingensis), although extremely fragmentary remains have been suggested as indicating earlier Varanus. The paleobiogeographic history of Varanus and timing for origin of its gigantism remain uncertain. Methodology/Principal Findings A new Varanus from the Mytilini Formation (Turolian, Miocene) of Samos, Greece is described. The holotype consists of a partial skull roof, right side of a braincase, partial posterior mandible, fragment of clavicle, and parts of six vertebrae. A cladistic analysis including 83 taxa coded for 5733 molecular and 489 morphological characters (71 previously unincluded) demonstrates that the new fossil is a nested member of an otherwise exclusively East Asian Varanus clade. The new species is the earliest-known giant (>600 mm PCL) terrestrial lizard. Importantly, this species co-existed with a diverse continental mammalian fauna. Conclusions/Significance The new monitor is larger (longer) than 99% of known fossil and living lizards. Varanus includes, by far, the largest limbed squamates today. The only extant non-snake squamates that approach monitors in maximum size are the glass-snake Pseudopus and the worm-lizard Amphisbaena. Mosasauroids were larger, but exclusively marine, and occurred only during the Late Cretaceous. Large, extant, non-Varanus, lizards are limbless and/or largely isolated from mammalian competitors. By contrast, our new Varanus achieved gigantism in a continental environment populated by diverse eutherian mammal competitors. PMID:22900001

  18. Bone deformities and skeletal malformations in the Roman Imperial Age.

    PubMed

    Minozzi, Simona; Catalano, Paola; Pantano, Walter; Caldarini, Carla; Fornaciari, Gino

    2014-01-01

    This paper describes some cases of individuals affected by skeletal deformities resulting in "freak" appearance. The skeletal remains were found during large archaeological excavations in the Roman territory, carried out by the Special Superintendence to the Archeological Heritage of Rome in the last years, dated back to the Imperial Age. The first cases reported are referred to two growth disorders with opposite effects: a case of dwarfism and another of gigantism. The former concerns a young man from the Collatina necropolis with very short and malformed limbs, which allowed a diagnosis of acondroplasic dwarfism, a rare congenital disorder that limits height below 130 cm. The latter case comes from the necropolis of Torre Serpentana in Fidenae, and is instead referred to a young person of very high stature, about 204 cm, suffering from Gigantism, a rare condition which in this case seems to have been linked to a hormonal dysfunction due to a pituitary adenoma. A third case regards a joint disease affecting the vertebral column and causing severe deformities. The skeleton was found in the Collatina necropolis and belongs to an old woman, suffering from ankylosing spondylitis. Finally, the last and very peculiar case is related to an individual recovered in the necropolis of Castel Malnome. The skeletal remains belong to an adult man with a complete fusion of the temporo-mandibular joint, which compromised mastication and caused severe deformation of the maxillofacial complex. These cases are described in detail together with the possible implications that these deformities could have on in the social context. PMID:25702379

  19. Atmospheric oxygen concentration controls the size history of foraminifers

    NASA Astrophysics Data System (ADS)

    Payne, J.; Jost, A. B.; Ouyang, X.; Skotheim, J. M.; Wang, S. C.

    2010-12-01

    Body size correlates with numerous physiological traits and thus influences organism fitness. However, long-term controls on size evolution remain poorly understood because few datasets spans sufficiently long intervals. One proposed controlling factor is variation in atmospheric oxygen, which is widely argued to have influenced size evolution in numerous taxa, notably gigantism in arthropods during the late Paleozoic. In this study, we compiled a comprehensive genus- and species-level size database of foraminifers (marine protists) to enable an extensive analysis of factors influencing size evolution. Foraminifers are an ideal study group because they are present in all Phanerozoic periods and have been diverse and abundant in shallow-marine habitats since Devonian time. We observe significant correlation between foraminiferan size and atmospheric oxygen concentration in foraminifers as a whole and in half of the major subclades. Larger size is associated with higher oxygen concentrations, as predicted by simple physiological models based on changes in the ratio of surface area to volume. Because the oxygen content ocean waters is controlled in part by atmospheric pO2, we interpret the association between foraminiferan size and pO2 to result from a direct physiological effect of oxygen availability. Atmospheric oxygen concentration predicts foraminiferan size better than six other Phanerozoic time series (pCO2, sea level, number of named geological formations, ?18O, ?13C, 87Sr/86Sr), further suggesting the correlation between oxygen and size does not occur simply through some common geological cause that influences many aspects of Earth system history. These findings support the hypothesis that widespread Permo-Carboniferous gigantism was enabled by high pO2 and suggest that oxygen availability has been among the most important influences on size evolution through Phanerozoic time.

  20. Dinámica y crecimiento de los granos de polvo en la nebulosa protoplanetaria

    NASA Astrophysics Data System (ADS)

    de La Fuente Marcos, Carlos

    2001-06-01

    En el escenario estándar de la formación planetaria, los planetesimales (cuerpos de tamaño kilométrico) crecen a partir de granos de polvo, similares a los interestelares, embebidos en un disco gaseoso denominado nebulosa protoplanetaria. Durante esta etapa, los movimientos del gas pueden tener gran influencia en la dinámica y el crecimiento de los granos de polvo, dado que el flujo kepleriano del gas frena el movimiento de los mismos haciendo que caigan hacia el Sol, y la turbulencia inhibe la inestabilidad gravitacional de la capa de polvo. Aunque se acepta que los planetesimales fueron los elementos constituyentes de los planetas, todavía se desconoce cómo se produjo la formación de los mismos. Por esta razón, en los estudios más recientes, existe un renovado interés por comprender mejor la evolución de la capa de polvo inmersa en el disco gaseoso de la Nebulosa. El gas que fluye en el disco puede engendrar estructuras carentes de simetría axial, como por ejemplo ondas espirales y vórtices, a partir de gran variedad de mecanismos de excitación e inestabilidad. En 1995, Barge y Sommeria pusieron de manifiesto que la existencia de vórtices gaseosos persistentes en la nebulosa solar tendría importantes consecuencias sobre la formación de los planetesimales y el posterior crecimiento de los planetas gigantes. La investigación desarrollada en esta Tesis analiza la relación entre el polvo y el gas debida al acoplamiento por fricción dinámica entre ambos; en concreto, se estudia el efecto del flujo medio del gas sobre la dinámica de las partículas de polvo. El primer objetivo es investigar en profundidad los procesos de captura y crecimiento de los granos de polvo dentro de un vórtice y su posible relevancia en cuanto a la formación de los planetesimales. El segundo objetivo es la exploración de los efectos de ondas espirales propagándose en el disco gaseoso sobre la dinámica y el crecimiento de las partículas. La presencia de líneas de corriente no circulares perturba significativamente el movimiento de las partículas alrededor del Sol e incrementa su vida media en la Nebulosa. El flujo medio del gas se modela de forma simple, analizándose la dinámica y el crecimiento de las partículas mediante simulaciones numéricas. Al incrementarse la vida media y la densidad superficial de las partículas sólidas, los mecanismos de confinamiento derivados de la presencia de vórtices y ondas espirales actuan sobre el material sólido de la Nebulosa (mediante agregación colisional o inestabilidades gravitacionales) de manera mucho más eficiente que la previamente considerada. Esto ofrece nuevas posibilidades para la formación de planetesimales y núcleos de planetas gigantes, y puede explicar la formación rápida de planetas extrasolares gigantes. Además, esta Tesis analiza la respuesta de las partículas, en un disco protoplanetario con un radio de 100 UA en torno a una estrella de tipo solar, al campo gravitatorio derivado de la presencia de dos estrellas compañeras ligadas en una órbita relativamente elongada (300-1600 UA). Para llevar a cabo este análisis, se han realizado una serie de simulaciones numéricas de configuraciones jerárquicas coplanares utilizando un programa FORTRAN que integra directamente las ecuaciones del movimiento con el objeto de modelar la presencia de las fuerzas gravitacionales y viscosas. El disco protoplanetario masivo se encuentra en torno a una de las componentes de la binaria. La evolución temporal del subdisco de polvo depende directamente de la naturaleza (directa o retrógrada) de la revolución relativa de la compañera estelar, y de la temperatura y la masa del disco circunestelar.

  1. The Geometric Characteristics and Initiation Mechanisms of the Earthquake- Triggered Daguangbao Landslide

    NASA Astrophysics Data System (ADS)

    Dong, J. J.; Tsao, C. C.; Yang, C. M.; Wu, W. J.; Lee, C. T.; Lin, M. L.; Zhang, W. F.; Pei, X. J.; Wang, G. H.; Huang, R.

    2014-12-01

    Recently, catastrophic landslides are getting considerable attentions not only from natural hazard but also from geo-material science. In the past century, the Daguangbao (DGB) landslide which triggered by the Wenchuan earthquake is one of the largest earthquake- triggered landslides. Our main goal is to characterize the geometry of DGB landslide to better determine the initiation mechanisms. Based on the remote sensing images analysis and field investigation, we proposed an atypical wedge model of DGB landslide compose of a folded strata and a zigzag stepping-out joint system, which outcropped at the south and north of the landslide site, respectively. The intersection line of wedge is curved, counterclockwise rotated and daylighted, which fit the pre- and post- position of the mining tent with 1.9 km displacements. The volume of sliding mass was evaluated to 10.51×108 m3 by the atypical wedge model. The identified slip zone of DGB landslide consists of the breccia and gouge layers in the dolomite strata. The rotary-shear tests were performed with the intact dolomite rocks near the slip zone and the gouges in the slip zone to determine the strength of slip surface. The peak and the steady-state friction coefficient of the tested dry dolomite discontinuities, wet gouges are 0.52~0.96, 0.73~0.86 and 0.1~0.57, 0.16~0.63, respectively. Although the result of static wedge stability analysis shows that the slope is quite stable (F.S. = 4), but the result of pseudo-static wedge stability analysis with seismic coefficient will trigger the gigantic wedge by the Wenchuan earthquake. Moreover, the friction coefficient of the tested gouges after long slip displacements as shear velocity exceeds 1.3 m/s will lower than 0.25 (=tan(14°); the intersection line plunged 14°). Therefore, the gigantic wedge can be accelerated by the inertial force and keep moving rapidly with long run-out. According to the calculations of simple one dimensional particle motion model, DGB landslide traveled 52~68 seconds with a maximum velocity of 58~75 m/sec.

  2. The kinematics and initiation mechanisms of the earthquake-triggered Daguangbao landslide

    NASA Astrophysics Data System (ADS)

    Yang, Che-Ming; Cheng, Hui-Yun; Tsao, Chia-Che; Wu, Wen-Jie; Dong, Jia-Jyun; Lee, Chyi-Tyi; Lin, Ming-Lang; Zhang, Wei-Fong; Pei, Xiang-Jun; Wang, Gong-Hui; Huang, Run-Qiu

    2015-04-01

    The Daguangbao (DGB) landslide is one of the largest earthquake-triggered landslides induced by the 2008 Wenchuan earthquake in the world over the past century. Based on remote sensing images, topography analysis and field investigation, this landslide was speculated a gigantic atypical wedge failure with the folded bedding plane and a zigzag stepping-out joint system, which outcropped at the south and north, respectively. With the inferred failure surfaces, the volume of the DGB landslide is about 1,051 Mm3. The frequently adopted Rigid Wedge Method (RWM), which assumed zero shear stress on the sliding surface along the vectors perpendicular to the intersection line when evaluating the wedge stability, could not be valid for this super large DGB wedge. Under an assumption that the shear strength is fully mobilized on the sliding surface along the vectors perpendicular to the intersection line, this study proposed to use a Maximum Shear Stress Method (MSSM) to calculate the factor of safety (FOS) of the DGB wedge. Based on the assumptions of the two methods, the FOS of the RWM and MSSM are the upper and lower bounds for the wedge stability analysis. Based on the rotary shear tests, the averaged friction coefficients of the representative materials of the two sliding surfaces are 0.79 (bedding parallel fault gauges) and 0.71 (dolomite joints). Without external force, the FOSs of the DGB landslide are 4.14 and 2.51 by the RWM and MSSM, respectively. Restate, the wedge is stable before the 2008 Wenchuan earthquake. However, DGB landslide can be triggered at 35.7 sec based on the ground acceleration records of strong motion station MZQP during the 2008 Wenchuan earthquake and the pseudo-static stability analysis incorporated into MSSM (Acceleration: EW=0.272g, NS=0.152g, Vertical=0.244g). Moreover, using the friction coefficient of the representative materials under large shear displacement under shear velocity of 1.3 m/s (0.16 for bedding parallel fault gouges and 0.1 for dolomite joints), the gigantic wedge can be speeded up to a maximum velocity of 54 m/sec. The traveled time will be 70 seconds with a travel distance of 1.9 km.

  3. Dynamics of Positive and Negative Streamers in Weak Uniform Electric Fields Between Thunderstorm Tops and the Lower Ionosphere

    NASA Astrophysics Data System (ADS)

    Liu, N.; Pasko, V. P.

    2003-12-01

    It is well established by now that transient luminous events (TLEs) observed at different altitudes above thunderstorms commonly consist of large numbers of needle-shaped filaments of ionization, called streamers [e.g., Gerken and Inan, JASTP, 65, 567, 2003; Su et al., Nature, 423, 974, 2003; Pasko, Nature, 423, 927, 2003; and references cited therein]. One of the important questions of the current TLEs research, which directly relates to the evaluation of the total volumes of atmosphere affected by these phenomena and possible role of some of the TLEs (i.e., sprites, jets and gigantic jets) in establishing a direct path of electrical contact between the tropospheric and mesospheric/lower ionospheric regions, is related to the determination of the minimum electric fields required for the propagation of streamers in air at different pressures [Pasko and George, JGR, 107, 1458, 2002]. The minimum field required for the propagation of positive streamers in air at ground pressure has been extensively documented experimentally and usually stays close to the value 4.4 kV/cm [Allen and Ghaffar, J. Phys. D Appl. Phys., 28, 331, 1995], in agreement with recent results of numerical simulations of positive streamers [Babaeva and Naidis, IEEE Trans. Plasma Sci., 25, 375, 1997; Morrow and Lowke, J. Phys. D Appl. Phys., 30, 614, 1997]. The information about the absolute value of the similar field for the negative streamers at present is very limited. The existing sources indicate that this field is a factor of 2-3 higher than the corresponding field for the positive streamers [e.g., Raizer, Gas Discharge Physics, 1991, p. 361; Babaeva and Naidis, 1997]. We note that although from the streamer similarity laws one generally would expect the minimum fields required for streamer propagation to scale with altitude proportionally to the air neutral density N, the actual scaling for the altitude range of sprites, jets and gigantic jets has not yet been verified experimentally, and a limited amount of data currently available in the literature [Griffiths and Phelps, Q.J.R. Meteorol. Soc., 102, 419, 1976; Bazelyan and Raizer, Spark Discharge, 1998, p. 216] indicate possible deviations from the N scaling. In this talk we will discuss conditions required for the propagation of streamers in air at different pressures and will present corresponding results from a new two-dimensional model, which has recently been developed at Penn State for studies of dynamics of streamers in weak uniform electric fields, documenting the minimum electric field magnitudes required for the propagation of positive and negative streamers at TLE altitudes.

  4. McCune Albright syndrome in association with excessive GH secretion: case report

    PubMed Central

    Özsu, Elif; Mutlu, Gül Ye?iltepe; Çizmecio?lu, Filiz Mine; Hatun, ?ükrü

    2015-01-01

    McCune-Albright Syndrome is a rare syndrome characterized with excessive function of peripheral endocrine organs and activating mutations of the stimulatory G protein alpha subunit are involved in the pathogenesis. The three main findings of the disease include hyperpigmented café au lait spots, fibrous dysplasia and increased endocrine functions and excessive secretion of growth hormone is observed in 21% of the patients. Clinical signs may be missed in these patients because of precocious puberty and craniofacial fibrous dysplasia. Since radiotherapy causes to sarcomatous changes and transsphenoidal surgery may cause to severe thickening in the cranial bones, they are not appropriate treatment options and medical treatment is recommended. Bromocriptine, cabergoline and octreotide or different combinations of these drugs are used in treatment and pegvisomant has also been used in recent years. Here, we present a male patient aged 12 years and 7 months to show gigantism as a rare clinical reflection of McCune-Albright Syndrome with an excessive height (197 cm), café au lait spots, growht hormone levels which could not be supressed with oral glucose tolerance test and increased prolactin levels. PMID:26265896

  5. McCune Albright syndrome in association with excessive GH secretion: case report.

    PubMed

    Özsu, Elif; Mutlu, Gül Ye?iltepe; Çizmecio?lu, Filiz Mine; Hatun, ?ükrü

    2015-06-01

    McCune-Albright Syndrome is a rare syndrome characterized with excessive function of peripheral endocrine organs and activating mutations of the stimulatory G protein alpha subunit are involved in the pathogenesis. The three main findings of the disease include hyperpigmented café au lait spots, fibrous dysplasia and increased endocrine functions and excessive secretion of growth hormone is observed in 21% of the patients. Clinical signs may be missed in these patients because of precocious puberty and craniofacial fibrous dysplasia. Since radiotherapy causes to sarcomatous changes and transsphenoidal surgery may cause to severe thickening in the cranial bones, they are not appropriate treatment options and medical treatment is recommended. Bromocriptine, cabergoline and octreotide or different combinations of these drugs are used in treatment and pegvisomant has also been used in recent years. Here, we present a male patient aged 12 years and 7 months to show gigantism as a rare clinical reflection of McCune-Albright Syndrome with an excessive height (197 cm), café au lait spots, growht hormone levels which could not be supressed with oral glucose tolerance test and increased prolactin levels. PMID:26265896

  6. The aureole of Olympus Mons (Mars) as the compound deposit of submarine landslides

    NASA Astrophysics Data System (ADS)

    De Blasio, Fabio Vittorio

    2011-12-01

    The enigmatic deposits building up the Olympus Mons aureole on Mars are likely among the largest landslide remnants in the Solar System. These deposits exhibit an extraordinary run-out distance (up to nearly 700 km), in spite of a fall height some 100 times smaller. After quantifying the mobility of the Olympus Mons aureole lobes it is suggested, based on dynamical considerations and morphological analysis, that the aureole could be the consequence of a series of gigantic subaqueous landslides. In order to bring evidence in favor of this interpretation, comparisons are drawn between the different landslide deposits on Earth and Mars, emphasizing the similarity with the rock avalanches of the Canary Islands and the Hawaii. The results of experimental subaqueous debris flows are also analyzed, and numerical calculations are introduced to simulate the dynamics of flow. In analogy with certain subaqueous landslides on Earth, it is possible that the outstanding run-out of the aureole lobes was a consequence of hydroplaning, a natural lubrication by water during flow.

  7. Planet Mars: Story of Another World

    NASA Astrophysics Data System (ADS)

    Leatherland, Alex

    2009-05-01

    Mars has captured the imagination of people throughout the ages, inspiring many stories. Remarkably, though, little was known about the red planet until recently. Through a great deal of exploration and theory, planetary scientists have striven to correct this situation. Over the course of the past half century, since the first flyby of Mars by NASA's Mariner 4 spacecraft in 1967, a multitude of probes have landed on, orbited, and flown past the planet. From these missions, a great deal has been learned about Mars. Its surface has now been studied to a respectable level of detail, revealing an astonishing amount of information about volcanoes such as Olympus Mons in Mars's Tharsis region; about the gigantic Valles Marineris (Valley of Wonder), the largest known canyon in the solar system; and about lava flows, outflow channels, and the Martian regolith, among many other aspects of the planet. This level of detail is made more incredible because of the difficulty in gathering such information. And there is still a staggering wealth of learning left to do. This book provides an overview of the current understanding of the past and present state of Mars, and a brief introduction to the planet.

  8. "So it really does exist-the sea-Serpent we've never believed in!" Ferenczi's influence on Freud revisited.

    PubMed

    Bonomi, Carlo

    2013-12-01

    In the last phase of his work, Ferenczi created a new language for trauma, based on the fragmentation of mental life. In the paper on "The principles of relaxation and neocatharsis," Ferenczi reformulated the goal of analysis by proposing that "no analysis can be regarded … as complete unless we have succeed in penetrating the traumatic material", where the "traumatic material" was not to be sought in the neurotic reactions and adaptive solutions of the ego but in more primitive reactions, such as the psychotic turning away from reality, splitting, and fragmentation. This was exactly the material that Freud assimilated in the essay "A disturbance of memory on the Acropolis", after the death of Ferenczi. Freud visited Athens in 1904, and the walk up to the Parthenon represented the successful coronation of his self-analysis. Actually, the hallucination turned out to be so uncanny that he never again visited Athens. In a letter to Fliess, written shortly before the meeting in Nuremberg, on January 24, 1897, Freud reported on a case history turning on a "scene about the circumcision of a girl," who later was convincingly identified by Schur as Emma Eckstein. Did Freud have the germinal idea that Emma Eckstein's hallucination of the penis contained the wish to overcome her trauma and the hope to have a restored genital? Is this the holy visitation, which haunted him on the Acropolis? Why did he give up the profound insight that the dreams of gigantic snakes had a traumatic origin? PMID:24309686

  9. Two sun-like superflare stars rotating as slow as the Sun*

    NASA Astrophysics Data System (ADS)

    Nogami, Daisaku; Notsu, Yuta; Honda, Satoshi; Maehara, Hiroyuki; Notsu, Shota; Shibayama, Takuya; Shibata, Kazunari

    2014-04-01

    We report on the results of high dispersion spectroscopy of two "superflare stars," KIC 9766237 and KIC 9944137 with Subaru/HDS. Superflare stars are G-type main sequence stars, but show gigantic flares compared to the Sun, which have recently been discovered in the data obtained with the Kepler spacecraft. Though most of these stars are thought to have a rotation period shorter than 10 d on the basis of photometric variabilities, the two targets of the present paper are estimated to have rotation periods of 21.8 d and 25.3 d. Our spectroscopic results clarified that these stars have stellar parameters similar to those of the Sun in terms of the effective temperature, surface gravity, and metallicity. The projected rotational velocities derived by us are consistent with the photometric rotation period, indicating a fairly high inclination angle. The average strength of the magnetic field on the surface of these stars are estimated to be 1-20 G, by using the absorption line of Ca II 8542. We could not detect any hint of binarity in our spectra, although more data are needed to firmly rule out the presence of an unseen low-mass companion. These results claim that the spectroscopic properties of these superflare stars are very close to those of the Sun, and support the hypothesis that the Sun might cause a superflare.

  10. Origin and evolution of marginal basins of the NW Pacific: Diffuse-plate tectonic reconstructions

    E-print Network

    Xu, Junyuan; Ben-Avraham, Zvi; Yu, Ho-Shing

    2012-01-01

    Formation of the gigantic linked dextral pull-apart basin system in the NW Pacific is due to NNE- to ENE-ward motion of east Eurasia. This mainly was a response to the Indo-Asia collision which started about 50 Ma ago. The displacement of east Eurasia can be estimated using three aspects: (1) the magnitude of pull-apart of the dextral pull-apart basin system, (2) paleomagnetic data from eastern Eurasia and the region around the Arctic, and (3) the shortening deficits in the Large Tibetan Plateau. All the three aspects indicate that there was a large amount (about 1200 km) of northward motion of the South China block and compatible movements of other blocks in eastern Eurasia during the rifting period of the basin system. Such large motion of the eastern Eurasia region contradicts any traditional rigid plate tectonic reconstruction, but agrees with the more recent concepts of non-rigidity of both continental and oceanic lithosphere over geological times. Based on these estimates, the method developed for resto...

  11. Wireless Transfer of Electricity in Outer Space

    E-print Network

    Alexander Bolonkin

    2008-05-07

    Author offers conclusions from his research of a revolutionary new idea - transferring electric energy in the hard vacuum of outer space wirelessly, using a plasma power cord as an electric cable (wire). He shows that a certain minimal electric currency creates a compressed force that supports the plasma cable in the compacted form. A large energy can be transferred hundreds of millions of kilometers by this method. The required mass of the plasma cable is only hundreds of grams. He computed the macroprojects: transference of hundreds kilowatts of energy to Earth Space Station, transferring energy to the Moon or back, transferring energy to a spaceship at distance 100 million of kilometers, the transfer energy to Mars when one is located at opposed side of the distant Sun, transfer colossal energy from one of Earth's continents to another continent (for example, between Europe-USA) wirelessly-using Earth ionosphere as cable, using Earth as gigantic storage of electric energy, using the plasma ring as huge MagSail for moving of spaceships. He also demonstrates that electric currency in a plasma cord can accelerate or brake spacecraft and space apparatus.

  12. Giant lizards occupied herbivorous mammalian ecospace during the Paleogene greenhouse in Southeast Asia

    PubMed Central

    Head, Jason J.; Gunnell, Gregg F.; Holroyd, Patricia A.; Hutchison, J. Howard; Ciochon, Russell L.

    2013-01-01

    Mammals dominate modern terrestrial herbivore ecosystems, whereas extant herbivorous reptiles are limited in diversity and body size. The evolution of reptile herbivory and its relationship to mammalian diversification is poorly understood with respect to climate and the roles of predation pressure and competition for food resources. Here, we describe a giant fossil acrodontan lizard recovered with a diverse mammal assemblage from the late middle Eocene Pondaung Formation of Myanmar, which provides a historical test of factors controlling body size in herbivorous squamates. We infer a predominately herbivorous feeding ecology for the new acrodontan based on dental anatomy, phylogenetic relationships and body size. Ranking body masses for Pondaung Formation vertebrates indicates that the lizard occupied a size niche among the larger herbivores and was larger than most carnivorous mammals. Paleotemperature estimates of Pondaung Formation environments based on the body size of the new lizard are approximately 2–5°C higher than modern. These results indicate that competitive exclusion and predation by mammals did not restrict body size evolution in these herbivorous squamates, and elevated temperatures relative to modern climates during the Paleogene greenhouse may have resulted in the evolution of gigantism through elevated poikilothermic metabolic rates and in response to increases in floral productivity. PMID:23740779

  13. Measuring engagement effectiveness in social media

    NASA Astrophysics Data System (ADS)

    Li, Lei; Sun, Tong; Peng, Wei; Li, Tao

    2012-03-01

    Social media is becoming increasingly prevalent with the advent of web 2.0 technologies. Popular social media websites, such as Twitter and Facebook, are attracting a gigantic number of online users to post and share information. An interesting phenomenon under this trend involves that more and more users share their experiences or issues with regard to a product, and then the product service agents use commercial social media listening and engagement tools (e.g. Radian6, Sysomos, etc.) to response to users' complaints or issues and help them tackle their problems. This is often called customer care in social media or social customer relationship management (CRM). However, all these existing commercial social media tools only provide an aggregated level of trends, patterns and sentiment analysis based on the keyword-centric brand relevant data, which have little insights for answering one of the key questions in social CRM system: how effective is our social customer care engagement? In this paper, we focus on addressing the problem of how to measure the effectiveness of engagement for service agents in customer care. Traditional CRM effectiveness measurements are defined under the scenario of the call center, where the effectiveness is mostly based on the duration time per call and/or number of answered calls per day. Different from customer care in a call center, we can obtain detailed conversations between agents and customers in social media, and therefore the effectiveness can be measured by analyzing the content of conversations and the sentiment of customers.

  14. Discovery of a rare arboreal forest-dwelling flying reptile (Pterosauria, Pterodactyloidea) from China.

    PubMed

    Wang, Xiaolin; Kellner, Alexander W A; Zhou, Zhonghe; Campos, Diogenes de Almeida

    2008-02-12

    A previously undescribed toothless flying reptile from northeastern China, Nemicolopterus crypticus gen. et sp. nov., was discovered in the lacustrine sediments of the Early Cretaceous Jiufotang Formation, western Liaoning, China. The specimen consists of an almost complete articulated skeleton (IVPP V14377) and, despite representing an immature individual, based on the ossification of the skeleton, it is not a hatchling or newborn, making it one of the smallest pterosaurs known so far (wing span approximately 250 mm). It can be distinguished from all other pterosaurs by the presence of a short medial nasal process, an inverted "knife-shaped" deltopectoral crest of the humerus, and the presence of a well developed posterior process on the femur above the articulation with the tibia. It further shows the penultimate phalanges of the foot curved in a degree not reported in any pterosaur before, strongly indicating that it had an arboreal lifestyle, more than any other pterodactyloid pterosaur known so far. It is the sister-group of the Ornithocheiroidea and indicates that derived pterosaurs, including some gigantic forms of the Late Cretaceous with wingspans of >6 m, are closely related to small arboreal toothless creatures that likely were living in the canopies of the ancient forests feeding on insects. PMID:18268340

  15. A new azhdarchid pterosaur from the Late Cretaceous of the Transylvanian Basin, Romania: implications for azhdarchid diversity and distribution.

    PubMed

    Vremir, Mátyás; Kellner, Alexander W A; Naish, Darren; Dyke, Gareth J

    2013-01-01

    We describe a new taxon of medium-sized (wing span ca. 3 m) azhdarchid pterosaur from the Upper Cretaceous Transylvanian Basin (Sebe? Formation) of Romania. This specimen is the most complete European azhdarchid yet reported, comprising a partially articulated series of vertebrae and associated forelimb bones. The new taxon is most similar to the Central Asian Azhdarcho lancicollis Nessov but possesses a suite of autapomorphies in its vertebrae that include the relative proportions of cervicals three and four and the presence of elongated prezygapophyseal pedicles. The new taxon is interesting in that it lived contemporaneously with gigantic forms, comparable in size to the famous Romanian Hatzegopteryx thambema. The presence of two distinct azhdarchid size classes in a continental depositional environment further strengthens suggestions that these pterosaurs were strongly linked to terrestrial floodplain and wooded environments. To support this discussion, we outline the geological context and taphonomy of our new specimen and place it in context with other known records for this widespread and important Late Cretaceous pterosaurian lineage. PMID:23382886

  16. Micromechanics of the pericellular matrix

    NASA Astrophysics Data System (ADS)

    Curtis, J. E.; Boehm, H.; Schmitz, C. H. J.; Spatz, J. P.

    2006-03-01

    In recent years, much attention has been directed towards the properties and activities of the cell surface. In particular, the coupling of the membrane to the underlying protein polymer network called the actin cortex plays an important role in many events. The other side of the cell surface is less studied, although it too has a bound polymer network comprised of gigantic cross-linked polysaccharides (sugars). Called the pericellular matrix (PCM), it is associated with many cells including fibroblasts, chondrocytes, endothelial and smooth muscle cells. Its thickness can vary from 10's of nanometers to 10 microns and it is associated with adhesion dependent events like migration and mitosis. Biologists often hypothesize that its viscoelastic properties are responsible for the modulation of cell adhesion activities. To investigate this proposal, we measure the PCM's viscoelasticity using microrheology and probe the sharpness of its edge and its mesh size. The elastic modulus of the PCM under different condition is determined, and we characterize the long, elastic cables that can be pulled from the PCM. These results are compared with an externally reconstituted model PCM on the cell surface.

  17. Circumstellar Disks and Outer Planet Formation

    E-print Network

    A. Lecavelier Des Etangs

    1998-06-16

    The dust disk around Beta Pic must be produced by collision or by evaporation of orbiting Kuiper belt-like objects. Here we present the Orbiting-Evaporating-Bodies scenario in which the disk is a gigantic multi-cometary tail supplied by slowly evaporating bodies like Chiron. If dust is produced by evaporation, a planet with an eccentric orbit can explain the observed asymmetry of the disk, because the periastron distribution of the parent bodies are then expected to be non-axisymmetric. We investigate the consequence for the Kuiper belt-like objects of the formation and the migration of an outer planet like Neptune in Fernandez's scheme (1982). We find that bodies trapped in resonance with a migrating planet can significantly evaporate, producing a Beta Pic-like disk with similar characteristics like opening angle and asymmetry. We thus show that the Beta Pic disk can be a transient phenomenon. The circumstellar disks around main sequence stars can be the signature of the present formation and migration of outer planets.

  18. Planetary migration and sources of dust in the Beta Pic disk

    E-print Network

    A. Lecavelier des Etangs

    1998-06-22

    The dust disk around Beta Pictoris must be produced by collision or by evaporation of orbiting Kuiper belt-like objects. Here we extend the already proposed Orbiting-Evaporating-Bodies (OEB) scenario in which the disk is a gigantic multi-cometary tail supplied by slowly evaporating bodies like Chiron. We show that the number of these OEBs must be several tens of millions, and that this is consistent with the number of bodies needed to explain the presence of CO and CI in the gaseous disk. We explore some possible origin of the required perturbation on the OEBs. If dust is produced by evaporation, a planet with an eccentric orbit can explain the observed asymmetry of the disk, because the periastron distribution of the parent bodies are then expected to be non-axisymmetric. Following Malhotra (1995), we investigate the consequence for the Kuiper belt-like objects of the formation and the migration of an outer planet like Neptune in Fernandez's scheme (Fernandez 1982). We find that bodies trapped in resonance with a migrating planet can significantly evaporate, producing a Beta Pictoris-like disk with similar characteristics like opening angle and asymmetry. We thus show that the Beta Pictoris disk can be a transient phenomenon. The circumstellar disks around main sequence stars can be the signature of the present formation and migration of outer planets.

  19. Catastrophic flood origin, little Missouri River valley, Montana, South Dakota, and North Dakota

    SciTech Connect

    Clausen, E.N.

    1988-07-01

    Mosaics of photographically reduced topographic maps demonstrate the Little Missouri River valley was developed by gigantic floods. Catastrophic flood landforms, oriented in a northwest-southeast direction, cross the entire Little Missouri drainage basin. Field evidence, consisting of abundant flood-deposited alluvium, supports map evidence. Flood-produced landforms, cut in easily eroded claystone bedrock, appear fresh, suggesting that floods occurred late during the last glacial cycle. Sheets of water, several hundred kilometers wide, flowed in a southeast direction, parallel with a continental ice margin. Erosion lowered the regional surface from a level corresponding to the tops of the highest present-day buttes to the surface now crossed by the headwaters of the Moreau, Grand, Cannonball, Heart, and Green Rivers. Spillway trenches served to channel flow and rapidly cut headward into easily eroded claystone. These trenches include the Moreau, Grand, Cannonball, Heart, and Missouri valleys. The Missouri valley in western North Dakota became the dominant spillway as tributary trenches systematically cut off flow feeding competing spillways. Formation of the Little Missouri spillway, first as a north-trending valley, progressively cut off floodwaters flowing into the Heart, Cannonball, Grand, and Moreau spillways. The north end of the Little Missouri spillway also was cut off by a deeper east-trending spillway. Huge sheets of floodwater continued to pour across the divide west of the Little Missouri continuing to lower that surface. These floodwaters were cut off by development of the Yellowstone spillway in eastern Montana.

  20. Constraints on early events in Martian history as derived from the cratering record

    SciTech Connect

    Barlow, N.G. )

    1990-08-30

    The shapes and densities of crater size-frequency distribution curves are used to constrain two major events early in Martian history: termination of high obliteration rates and viability of the multiple impact origin of the crustal dichotomy. Distribution curves of fresh craters superposed on uplands, intercrater plains, and ridged plains display shapes and densities indicative of formation prior to the end of heavy bombardment. This observation correlates with other geologic evidence, suggesting a major change in the erosional regime following the last major basin size impact (i.e., Argrye). In addition, the multisloped nature of the curves supports the idea that the downturn in the crater size-frequency distribution curves reflects the size-frequency distribution of the impactors rather than being the result of erosion. The crustal dichotomy formed prior to the heavy bombardment intermediate epoch based on distribution curves of knobby terrain; if the dichotomy resulted from a single gigantic impact, this observation places constraints on when this event happened. An alternate theory for dichotomy formation, the multiple-impact basin idea, is questioned: since distribution curves of large basins as well as heavy bombardment era units are not represented by a {minus}3 differential power law function, this study finds fewer basins missing on Mars compare to the Moon and Mercury than previously reported. The area covered by these missing basins is less than that covered the northern plains.

  1. A transparently scalable visualization architecture for exploring the universe.

    PubMed

    Fu, Chi-Wing; Hanson, Andrew J

    2007-01-01

    Modern astronomical instruments produce enormous amounts of three-dimensional data describing the physical Universe. The currently available data sets range from the solar system to nearby stars and portions of the Milky Way Galaxy, including the interstellar medium and some extrasolar planets, and extend out to include galaxies billions of light years away. Because of its gigantic scale and the fact that it is dominated by empty space, modeling and rendering the Universe is very different from modeling and rendering ordinary three-dimensional virtual worlds at human scales. Our purpose is to introduce a comprehensive approach to an architecture solving this visualization problem that encompasses the entire Universe while seeking to be as scale-neutral as possible. One key element is the representation of model-rendering procedures using power scaled coordinates (PSC), along with various PSC-based techniques that we have devised to generalize and optimize the conventional graphics framework to the scale domains of astronomical visualization. Employing this architecture, we have developed an assortment of scale-independent modeling and rendering methods for a large variety of astronomical models, and have demonstrated scale-insensitive interactive visualizations of the physical Universe covering scales ranging from human scale to the Earth, to the solar system, to the Milky Way Galaxy, and to the entire observable Universe. PMID:17093340

  2. Ultrafast observation of critical nematic fluctuations and giant magnetoelastic coupling in iron pnictides

    SciTech Connect

    Patz, Aaron; Li, Tianqi; ran, Sheng; Fernandes, Rafael M.; Schmalian, Joerg; Budko, Sergey L.; Canfield, Paul C.; Perakis, Ilias E.; Wang, Jigang

    2014-02-06

    Many of the iron pnictides have strongly anisotropic normal-state characteristics, important for the exotic magnetic and superconducting behaviour these materials exhibit. Y et, the origin of the observed anisotropy is unclear. Electronically driven nematicity has been suggested, but distinguishing this as an independent degree of freedom from magnetic and structural orders is dif?cult, as these couple together to break the same tetragonal symmetry. Here we use time-resolved polarimetry to reveal critical nematic ?uctuations in unstrained Ba(Fe1 À xCox)2As2. The femtosecond anisotropic response, which arises from the two-fold in-plane anisotropy of the complex refractive index, displays a characteristic two-step recovery absent in the isotropic response. The fast recovery appears only in the magnetically ordered state, whereas the slow one persists in the paramagnetic phase with a critical divergence approaching the structural transition temperature. The dynamics also reveal a gigantic magnetoelastic coupling that far exceeds electron–spin and electron–phonon couplings, opposite to conventional magnetic metals.

  3. Saving a life but losing the patient.

    PubMed

    Greene, Mark

    2013-12-01

    Gregor Samsa awakes to find himself transformed into a gigantic bug. The creature's inchoate flailing leads Gregor's sister to conclude that Gregor is no more, having been replaced by a brute beast lacking any vestige of human understanding. Sadly, real cases of brain injury and disease can lead to psychological metamorphoses so profound that we cannot easily think that the survivor is the person we knew. I argue that there can be cases in which statements like, "It's just not Gregor anymore," are not merely figures of speech. With this in mind, I consider three possible results of saving a biological life: (1) ordinary cases where saving the life will save the person, with strong duties to save the life; (2) cases where the intervention needed to save the life will replace the person, with strong duties not to save the life; (3) cases in which it is indeterminate whether the person will be saved or replaced. How should we think about indeterminate cases? Impersonal ethical considerations miss the point, while standard person-affecting considerations are inapplicable. I suggest turning attention away from survival towards a richer focus on what I call "personal concern." I show how considerations of personal concern, unlike those of self-interest, need not be tied to survival and how this allows personal concern to provide a basis for ethically substantive discussion of cases where saving a life might result in losing the patient. PMID:24293085

  4. Giant lizards occupied herbivorous mammalian ecospace during the Paleogene greenhouse in Southeast Asia.

    PubMed

    Head, Jason J; Gunnell, Gregg F; Holroyd, Patricia A; Hutchison, J Howard; Ciochon, Russell L

    2013-07-22

    Mammals dominate modern terrestrial herbivore ecosystems, whereas extant herbivorous reptiles are limited in diversity and body size. The evolution of reptile herbivory and its relationship to mammalian diversification is poorly understood with respect to climate and the roles of predation pressure and competition for food resources. Here, we describe a giant fossil acrodontan lizard recovered with a diverse mammal assemblage from the late middle Eocene Pondaung Formation of Myanmar, which provides a historical test of factors controlling body size in herbivorous squamates. We infer a predominately herbivorous feeding ecology for the new acrodontan based on dental anatomy, phylogenetic relationships and body size. Ranking body masses for Pondaung Formation vertebrates indicates that the lizard occupied a size niche among the larger herbivores and was larger than most carnivorous mammals. Paleotemperature estimates of Pondaung Formation environments based on the body size of the new lizard are approximately 2-5°C higher than modern. These results indicate that competitive exclusion and predation by mammals did not restrict body size evolution in these herbivorous squamates, and elevated temperatures relative to modern climates during the Paleogene greenhouse may have resulted in the evolution of gigantism through elevated poikilothermic metabolic rates and in response to increases in floral productivity. PMID:23740779

  5. Before the Giants: APASS Support to Ambitious Ground-based Galaxy Investigations and Space Missions Serching for Exo-Earths (Abstract)

    NASA Astrophysics Data System (ADS)

    Munari, U.

    2015-06-01

    (Abstract only) A huge, worldwide effort is underway to reconstruct the structure, kinematics and evolution of our Galaxy with optical spectroscopic techniques, which provide radial velocities and individual chemical abundances in addition to derive fundamental stellar parameters like surface temperature and gravity. RAVE has used for ten years (2003-2013) the 6dF 150-fiber positioner at the 1.3-meter UK Schmidt telescope in Siding Spring, ESO-Gaia has hundreds of nights allocated at the VLT telescopes in Chile with UVES and GIRAFFE multi-fiber instruments, GALAH has been allocated 400 nights in five years with the 400-fiber HERMES spectrograph at the 4-meter Australian telescope. Common to the millions of stars targeted by these surveys (over the range 10 < V < 16 mag) is the lack of suitable, multi-band, accurate optical photometry. In this talk, I review the fundamental role played by APASS in providing such missing photometric information for the stars targeted by these gigantic spectroscopic surveys. The APASS BVgri data are fundamental to support the spectroscopic effort, for example to constrain (when modelled together with 2MASS infrared JHK photometry) the stellar temperature. The APASS data are also crucial in fixing the interstellar reddening and the distance to the target stars, and their importance will be further expanded when APASS ultraviolet (u) and far red (z,Y) magnitudes will become available, as well the unsaturated APASS extension to brighter stars so that most of the bright spectroscopic standards will become within photometric reach.

  6. Fusion: A true challenge for an enormous reward

    NASA Astrophysics Data System (ADS)

    Ongena, J.

    2015-08-01

    From nuclear physics we know that energy can be released not only from the fission of heavy nuclei but also from the fusion of light nuclei. Steady progress shows that fusion—one of the few possible options for the future—can be a clean and safe solution for mankind's long-term energy needs, with minimal environmental impact. A source of energy which would be inexhaustible, inherently safe and environmentally friendly, is this not a marvellous prospect? Nuclear fusion has been the energy source of our Sun and the stars in the universe for billions of years. This process requires temperatures of tens of millions of degrees, so extremely high and foreign to our daily experience as to seem out of reach. Nevertheless, these extremely high temperatures are routinely realised in several laboratories all over the world, and since the early 1990s, large amounts of energy have been released in a controlled way from fusion reactions. We are witnessing the birth of a new technology destined to meet the gigantic future energy needs of mankind with minimal impact on the environment.

  7. Creating the brain and interacting with the brain: an integrated approach to understanding the brain.

    PubMed

    Morimoto, Jun; Kawato, Mitsuo

    2015-03-01

    In the past two decades, brain science and robotics have made gigantic advances in their own fields, and their interactions have generated several interdisciplinary research fields. First, in the 'understanding the brain by creating the brain' approach, computational neuroscience models have been applied to many robotics problems. Second, such brain-motivated fields as cognitive robotics and developmental robotics have emerged as interdisciplinary areas among robotics, neuroscience and cognitive science with special emphasis on humanoid robots. Third, in brain-machine interface research, a brain and a robot are mutually connected within a closed loop. In this paper, we review the theoretical backgrounds of these three interdisciplinary fields and their recent progress. Then, we introduce recent efforts to reintegrate these research fields into a coherent perspective and propose a new direction that integrates brain science and robotics where the decoding of information from the brain, robot control based on the decoded information and multimodal feedback to the brain from the robot are carried out in real time and in a closed loop. PMID:25589568

  8. Creating the brain and interacting with the brain: an integrated approach to understanding the brain

    PubMed Central

    Morimoto, Jun; Kawato, Mitsuo

    2015-01-01

    In the past two decades, brain science and robotics have made gigantic advances in their own fields, and their interactions have generated several interdisciplinary research fields. First, in the ‘understanding the brain by creating the brain’ approach, computational neuroscience models have been applied to many robotics problems. Second, such brain-motivated fields as cognitive robotics and developmental robotics have emerged as interdisciplinary areas among robotics, neuroscience and cognitive science with special emphasis on humanoid robots. Third, in brain–machine interface research, a brain and a robot are mutually connected within a closed loop. In this paper, we review the theoretical backgrounds of these three interdisciplinary fields and their recent progress. Then, we introduce recent efforts to reintegrate these research fields into a coherent perspective and propose a new direction that integrates brain science and robotics where the decoding of information from the brain, robot control based on the decoded information and multimodal feedback to the brain from the robot are carried out in real time and in a closed loop. PMID:25589568

  9. Space weather modeling using artificial neural network. (Slovak Title: Modelovanie kozmického po?asia umelou neurónovou sietou)

    NASA Astrophysics Data System (ADS)

    Valach, F.; Revallo, M.; Hejda, P.; Bochní?ek, J.

    2010-12-01

    Our modern society with its advanced technology is becoming increasingly vulnerable to the Earth's system disorders originating in explosive processes on the Sun. Coronal mass ejections (CMEs) blasted into interplanetary space as gigantic clouds of ionized gas can hit Earth within a few hours or days and cause, among other effects, geomagnetic storms - perhaps the best known manifestation of solar wind interaction with Earth's magnetosphere. Solar energetic particles (SEP), accelerated to near relativistic energy during large solar storms, arrive at the Earth's orbit even in few minutes and pose serious risk to astronauts traveling through the interplanetary space. These and many other threats are the reason why experts pay increasing attention to space weather and its predictability. For research on space weather, it is typically necessary to examine a large number of parameters which are interrelated in a complex non-linear way. One way to cope with such a task is to use an artificial neural network for space weather modeling, a tool originally developed for artificial intelligence. In our contribution, we focus on practical aspects of the neural networks application to modeling and forecasting selected space weather parameters.

  10. Theory of supercoupling, squeezing wave energy, and field confinement in narrow channels and tight bends using {epsilon} near-zero metamaterials

    SciTech Connect

    Silveirinha, Mario G.; Engheta, Nader

    2007-12-15

    In this work, we investigate the detailed theory of the supercoupling, anomalous tunneling effect, and field confinement originally identified by Silveirinha and Engheta [Phys. Rev. Lett. 97, 157403 (2006)], where we demonstrated the possibility of using materials with permittivity {epsilon} near zero to drastically improve the transmission of electromagnetic energy through a narrow irregular channel with very subwavelength transverse cross section. Here, we present additional physical insights, describe applications of the tunneling effect in relevant waveguide scenarios (e.g., the 'perfect' or 'super' waveguide coupling), and study the effect of metal losses in the metallic walls and the possibility of using near-zero {epsilon} materials to confine energy in a subwavelength cavity with gigantic field enhancement. In addition, we systematically study the propagation of electromagnetic waves through narrow channels filled with anisotropic near-zero {epsilon} materials. It is demonstrated that these materials may have interesting potentials, and that for some particular geometries, the reflectivity of the channel is independent of the specific dimensions or parameters of near-zero {epsilon} transition. We also describe several realistic metamaterial implementations of the studied problems, based on standard metallic waveguides, microstrip line configurations, and wire media.

  11. The evolutionary physiology of animal flight: paleobiological and present perspectives.

    PubMed

    Dudley, R

    2000-01-01

    Recent geophysical analyses suggest the presence of a late Paleozoic oxygen pulse beginning in the late Devonian and continuing through to the late Carboniferous. During this period, plant terrestrialization and global carbon deposition resulted in a dramatic increase in atmospheric oxygen levels, ultimately yielding concentrations potentially as high as 35% relative to the contemporary value of 21%. Such hyperoxia of the late Paleozoic atmosphere may have physiologically facilitated the initial evolution of insect flight metabolism. Widespread gigantism in late Paleozoic insects and other arthropods is also consistent with enhanced oxygen flux within diffusion-limited tracheal systems. Because total atmospheric pressure increases with increased oxygen partial pressure, concurrently hyperdense conditions would have augmented aerodynamic force production in early forms of flying insects. By the late Permian, evolution of decompositional microbial and fungal communities, together with disequilibrium in rates of carbon deposition, gradually reduced oxygen concentrations to values possibly as low as 15%. The disappearance of giant insects by the end of the Permian is consistent with extinction of these taxa for reasons of asphyxiation on a geological time scale. As with winged insects, the multiple historical origins of vertebrate flight in the late Jurassic and Cretaceous correlate temporally with periods of elevated atmospheric oxygen. Much discussion of flight performance in Archaeopteryx assumes a contemporary atmospheric composition. Elevated oxygen levels in the mid- to late Mesozoic would, however, have facilitated aerodynamic force production and enhanced muscle power output for ancestral birds, as well as for precursors to bats and pterosaurs. PMID:10845087

  12. Reduced genetic variation in the Japanese giant salamander, Andrias japonicus (Amphibia: Caudata).

    PubMed

    Matsui, Masafumi; Tominaga, Atsushi; Liu, Wan-zhao; Tanaka-Ueno, Tomoko

    2008-10-01

    The phylogenetic relationships among 46 samples from 27 populations of the Japanese giant salamander, Andriasjaponicus and its congener, A. davidianus from China was investigated, using 3664 bp sequences of the mitochondrial genes NADH1, NADH3, cyt b and CR, partial NADH6 and intervening genes. In phylogenetic trees constructed by MP, ML, and Bayesian methods, the family Cryptobranchidae and the genus Andrias both form monophyletic groups. Japanese A. japonicus and Chinese A. davidianus are sister taxa and can be regarded as separate species despite a small degree of genetic differentiation. Andriasjaponicus is divided into central and western clades, but the phylogenetic relationships within the latter clade are unresolved. As previously reported from allozyme analyses, A. japonicus exhibits little genetic differentiation, in strong contrast to salamanders of the genus Hynobius with which their distributions overlap. This reduced genetic variability in A. japonicus is attributable to a unique mating system of polygyny, delayed sexual maturity, notable longevity, life in a stable aquatic environment, and gigantism, as well as bottleneck effects following habitat fragmentation and extinction of local populations during Quaternary glaciations. The species is thus susceptible to extinction by potential environmental fluctuations, and requires extensive conservation measures. PMID:18723097

  13. A New Azhdarchid Pterosaur from the Late Cretaceous of the Transylvanian Basin, Romania: Implications for Azhdarchid Diversity and Distribution

    PubMed Central

    Vremir, Mátyás; Kellner, Alexander W. A.; Naish, Darren; Dyke, Gareth J.

    2013-01-01

    We describe a new taxon of medium-sized (wing span ca. 3 m) azhdarchid pterosaur from the Upper Cretaceous Transylvanian Basin (Sebe? Formation) of Romania. This specimen is the most complete European azhdarchid yet reported, comprising a partially articulated series of vertebrae and associated forelimb bones. The new taxon is most similar to the Central Asian Azhdarcho lancicollis Nessov but possesses a suite of autapomorphies in its vertebrae that include the relative proportions of cervicals three and four and the presence of elongated prezygapophyseal pedicles. The new taxon is interesting in that it lived contemporaneously with gigantic forms, comparable in size to the famous Romanian Hatzegopteryx thambema. The presence of two distinct azhdarchid size classes in a continental depositional environment further strengthens suggestions that these pterosaurs were strongly linked to terrestrial floodplain and wooded environments. To support this discussion, we outline the geological context and taphonomy of our new specimen and place it in context with other known records for this widespread and important Late Cretaceous pterosaurian lineage. PMID:23382886

  14. Landslides in Valles Marineris, Mars

    NASA Technical Reports Server (NTRS)

    Lucchitta, B. K.

    1979-01-01

    The morphology of the landslides in the Martian equatorial troughs, the geologic structure of the troughs, the time of emplacement, the similarity to terrestrial landslides, and the origin and mechanism of transport are analyzed. About 35 large landslides well-resolved on Viking images were examined, and it is found that the major landslides cover 31,000 sq km of the trough floors, and individual slides range in area from 40 to 7000 sq km. The morphologic variations of the landslides can be attributed mainly to their degree of confinement on trough floors. Many prominent landslides appear to be of similar age and were emplaced after a major faulting that dropped the trough floors. Most sliding occurred after the created scarps were dissected into spurs, gullies, and tributary canyons. Emplacement of the landslides approximately coincided with a late episode of major eruptive activity of the Tharsis volcanoes, and it is suggested that the slides may have originated as gigantic mudflows with slump blocks at their heads. The large size of many landslides is due to the fault scarps as high as 7 km on which they formed in the absence of vigorous fluvial erosion. The landslides suggest that Mars is earthlike in some respects, which may be important for further evaluations.

  15. Developmental palaeontology in synapsids: the fossil record of ontogeny in mammals and their closest relatives

    PubMed Central

    Sánchez-Villagra, Marcelo R.

    2010-01-01

    The study of fossilized ontogenies in mammals is mostly restricted to postnatal and late stages of growth, but nevertheless can deliver great insights into life history and evolutionary mechanisms affecting all aspects of development. Fossils provide evidence of developmental plasticity determined by ecological factors, as when allometric relations are modified in species which invaded a new space with a very different selection regime. This is the case of dwarfing and gigantism evolution in islands. Skeletochronological studies are restricted to the examination of growth marks mostly in the cement and dentine of teeth and can provide absolute age estimates. These, together with dental replacement data considered in a phylogenetic context, provide life-history information such as maturation time and longevity. Palaeohistology and dental replacement data document the more or less gradual but also convergent evolution of mammalian growth features during early synapsid evolution. Adult phenotypes of extinct mammals can inform developmental processes by showing a combination of features or levels of integration unrecorded in living species. Some adult features such as vertebral number, easily recorded in fossils, provide indirect information about somitogenesis and hox-gene expression boundaries. Developmental palaeontology is relevant for the discourse of ecological developmental biology, an area of research where features of growth and variation are fundamental and accessible among fossil mammals. PMID:20071389

  16. Why did not the Ontong Java Plateau form subaerially? [rapid communication

    NASA Astrophysics Data System (ADS)

    Korenaga, Jun

    2005-06-01

    A recent drilling leg on the Ontong Java Plateau and subsequent studies have consolidated the following observation for this gigantic oceanic plateau: The bulk of the plateau was formed at ˜ 120 Ma in a submarine environment. This rapid construction of a massive igneous body below sea level is impossible to explain with the popular plume head hypothesis. Though the bolide impact hypothesis for oceanic plateaus has recently been resurrected to offer an alternative, it is shown here that it fails to explain submarine eruption for exactly the same reason why the plume hypothesis fails. As a more dynamically promising model, the entrainment of dense fertile mantle by rapid seafloor spreading is proposed to account for voluminous magmatism in the submarine environment. It is also suggested that this chemically dense source mantle may naturally explain the anomalous subsidence history of this plateau as well as minor magmatism observed at ˜ 90 Ma. Modeling the dynamics of compositionally heterogeneous mantle and its geochemical consequences remains as a challenging yet rewarding problem in mantle dynamics and igneous petrology.

  17. Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly.

    PubMed

    Martín-Rodríguez, Juan F; Muñoz-Bravo, Jose L; Ibañez-Costa, Alejandro; Fernandez-Maza, Laura; Balcerzyk, Marcin; Leal-Campanario, Rocío; Luque, Raúl M; Castaño, Justo P; Venegas-Moreno, Eva; Soto-Moreno, Alfonso; Leal-Cerro, Alfonso; Cano, David A

    2015-01-01

    Acromegaly is a disorder resulting from excessive production of growth hormone (GH) and consequent increase of insulin-like growth factor 1 (IGF-I), most frequently caused by pituitary adenomas. Elevated GH and IGF-I levels results in wide range of somatic, cardiovascular, endocrine, metabolic, and gastrointestinal morbidities. Subcutaneous implantation of the GH-secreting GC cell line in rats leads to the formation of tumors. GC tumor-bearing rats develop characteristics that resemble human acromegaly including gigantism and visceromegaly. However, GC tumors remain poorly characterized at a molecular level. In the present work, we report a detailed histological and molecular characterization of GC tumors using immunohistochemistry, molecular biology and imaging techniques. GC tumors display histopathological and molecular features of human GH-producing tumors, including hormone production, cell architecture, senescence activation and alterations in cell cycle gene expression. Furthermore, GC tumors cells displayed sensitivity to somatostatin analogues, drugs that are currently used in the treatment of human GH-producing adenomas, thus supporting the GC tumor model as a translational tool to evaluate therapeutic agents. The information obtained would help to maximize the usefulness of the GC rat model for research and preclinical studies in GH-secreting tumors. PMID:26549306

  18. Using a smart phone application to measure high-energy radiation from thunderstorms

    NASA Astrophysics Data System (ADS)

    Bowers, G. S.; Smith, D. M.; Rexroad, W. Z.; Kelley, N. A.; Martinez-Mckinney, F.; Rubenstein, E. P.; Drukier, G.; Benes, G. N.

    2013-12-01

    Commercial airline flights and developing cell phone technologies present a burgeoning opportunity for the public to help investigate radiation from thunderstorms, including terrestrial gamma-ray flashes (TGFs), longer-lived gamma-ray glows, x-rays from lightning stepped leaders, and possible high-energy radiation, never yet observed, from blue jets, gigantic jets, and blue starters. GammaPix is a smartphone application from Image Insight, Inc. that uses the camera's CCD or CMOS sensor to identify and qualitatively assess threats related to gamma radioactivity, e.g., those caused by accidental exposure to radioactive material, high-altitude air travel, or acts of terrorism. A science-oriented version of the app is under development that will be publicized for use aboard commercial airline flights and on the ground in regions (like Japan in the wintertime) where thunderstorm charge centers come close to the ground. The primary goal of the project is to learn whether TGFs close to passenger aircraft and population centers on the ground occur often enough to create concern about radiation risk.

  19. Revolutionising landscapes: Hydroelectricity and the heavy industrialisation of society and environment in the Comte de Beauharnois, 1927--1948

    NASA Astrophysics Data System (ADS)

    Pelletier, Louis-Raphael

    This dissertation analyses the rapid industrialisation of the rural Comte de Beauharnois and the adjacent stretch of the Fleuve Saint-Laurent owing to the construction, between 1929 and 1948, of a gigantic canal for hydroelectricity production and navigation by an electricity corporation called the Beauharnois Light Heat and Power (BLH&P). Using principally the archives of the BLH&P---especially its complaints files and its rich photographic record---this thesis argues that this process exemplifies the finance capitalist reorganisation of the society and ecosystems of the Canadian province of Quebec from the 19th century to the Great Depression. In keeping with recent work in environmental history, the transformation of rural landscapes and a river for heavy industry is described as an important dimension of a revolution in modes of production. More specifically, I argue that, in the case under study, the finance-capitalist reorganisation of Quebec revolved around two central and explicit projects, one social and the other environmental: the grouping of most individuals in an industrial working class without control over the means of production and the reorganisation of rural landscapes into reservoirs of modern energy and industrial natural resources.

  20. Giant blocks in the South Kona landslide, Hawaii

    USGS Publications Warehouse

    Moore, J.G.; Bryan, W.B.; Beeson, M.H.; Normark, W.R.

    1995-01-01

    A large field of blocky sea-floor hills, up to 10km long and 500 high, are gigantic slide blocks derived from the west flank of Mauna Loa volcano on the island of Hawaii. These megablocks are embedded in the toe of the south Kona landslide, which extends ~80km seaward from the present coastline to depths of nearly 5km. A 10-15km-wide belt of numerous, smaller, 1-3 km-long slide blocks separates the area of giant blocks from two submarine benches at depths of 2600 and 3700m depth that terminate seaward 20 to 30km from the shoreline. Similar giant blocks are found on several other major submarine Hawaiian landslides, including those north of Oahu and Molokai, but the South Kona blocks are the first to be examined in detail using high-resolution bathymetry, dredging, and submersible diving. Dredging of two of the giant blocks brought up pillowed tholeiitic lava. Megablocks were carried by a late Pleistocene giant landslide 40-80km west from the ancestral shoreline of Mauna Loa volcano before growth of the midslope benches by later slump movement. -from Authors

  1. Sex-specific effects of a parasite evolving in a female-biased host population

    PubMed Central

    2012-01-01

    Background Males and females differ in many ways and might present different opportunities and challenges to their parasites. In the same way that parasites adapt to the most common host type, they may adapt to the characteristics of the host sex they encounter most often. To explore this hypothesis, we characterized host sex-specific effects of the parasite Pasteuria ramosa, a bacterium evolving in naturally, strongly, female-biased populations of its host Daphnia magna. Results We show that the parasite proliferates more successfully in female hosts than in male hosts, even though males and females are genetically identical. In addition, when exposure occurred when hosts expressed a sexual dimorphism, females were more infected. In both host sexes, the parasite causes a similar reduction in longevity and leads to some level of castration. However, only in females does parasite-induced castration result in the gigantism that increases the carrying capacity for the proliferating parasite. Conclusions We show that mature male and female Daphnia represent different environments and reveal one parasite-induced symptom (host castration), which leads to increased carrying capacity for parasite proliferation in female but not male hosts. We propose that parasite induced host castration is a property of parasites that evolved as an adaptation to specifically exploit female hosts. PMID:23249484

  2. The change of amyloplasts structure and composition of storage starch in potato minitubers during imitated microgravity

    NASA Astrophysics Data System (ADS)

    Nedukha, O. M.; Kordyum, E. L.; Martyn, G. M.; Schnyukova, E. I.

    Potato was designated for food production in the controlled ecological life-support system CELSS because its tubers as it is known contain starch and significant protein content and are edible food after the long-term storage We used the cultivation of potato miniplants under influence of long-term horizontal clinorotation 2 rev min which imitated microgravity as a model for the technology of potato food production in the CELSS The aim of our work was to determine content and composition storage starch as well as amyloplast ultrastructure of storage parenchyma cells in potato minitubers formed under long-term to 6 weeks slow horizontal clinorotation 2 rpm Minitubers developed from axillary buds of potato miniplants growing in the aseptic stationary conditions and under clinorotation Methods of scanning and transmission electron microscopy were used for the study of surface and ultrastructure of amyloplasts the biochemical method by Hovenkamp-Hermelink et al 1988 - for study of starch composition Some differences were observed in amyloplast structure under clinorotation namely increased volume of starch grains in plastid decreased stroma volume changed structure of envelope membranes in comparison with the stationary control Besides an appearance of fraction of gigantic amyloplasts in central layers of parenchyma was observed under clinorotation after 4 weeks of growth The total starch content increased and reached to 219 5 - 4 1 mg g FW at 6 weeks of clinorotation it was 167 5 - 5 6 mg g FW in the control minitubers A ratio of

  3. The First Freshwater Mosasauroid (Upper Cretaceous, Hungary) and a New Clade of Basal Mosasauroids

    PubMed Central

    Makádi, László; Caldwell, Michael W.; ?si, Attila

    2012-01-01

    Mosasauroids are conventionally conceived of as gigantic, obligatorily aquatic marine lizards (1000s of specimens from marine deposited rocks) with a cosmopolitan distribution in the Late Cretaceous (90–65 million years ago [mya]) oceans and seas of the world. Here we report on the fossilized remains of numerous individuals (small juveniles to large adults) of a new taxon, Pannoniasaurus inexpectatus gen. et sp. nov. from the Csehbánya Formation, Hungary (Santonian, Upper Cretaceous, 85.3–83.5 mya) that represent the first known mosasauroid that lived in freshwater environments. Previous to this find, only one specimen of a marine mosasauroid, cf. Plioplatecarpus sp., is known from non-marine rocks in Western Canada. Pannoniasaurus inexpectatus gen. et sp. nov. uniquely possesses a plesiomorphic pelvic anatomy, a non-mosasauroid but pontosaur-like tail osteology, possibly limbs like a terrestrial lizard, and a flattened, crocodile-like skull. Cladistic analysis reconstructs P. inexpectatus in a new clade of mosasauroids: (Pannoniasaurus (Tethysaurus (Yaguarasaurus, Russellosaurus))). P. inexpectatus is part of a mixed terrestrial and freshwater faunal assemblage that includes fishes, amphibians turtles, terrestrial lizards, crocodiles, pterosaurs, dinosaurs and birds. PMID:23284766

  4. Undulatory Locomotion

    E-print Network

    Cohen, Netta

    2009-01-01

    Undulatory locomotion is a means of self-propulsion that relies on the generation and propagation of waves along a body. As a mode of locomotion it is primitive and relatively simple, yet can be remarkably robust. No wonder then, that it is so prevalent across a range of biological scales from motile bacteria to gigantic prehistoric snakes. Key to understanding undulatory locomotion is the body's interplay with the physical environment, which the swimmer or crawler will exploit to generate propulsion, and in some cases, even to generate the underlying undulations. This review focuses by and large on undulators in the low Reynolds numbers regime, where the physics of the environment can be much more tractable. We review some key concepts and theoretical advances, as well as simulation tools and results applied to selected examples of biological swimmers. In particular, we extend the discussion to some simple cases of locomotion in non-Newtonian media as well as to small animals, in which the nervous system, mo...

  5. Sale of US military aircraft to Saudi Arabia. Master`s thesis

    SciTech Connect

    Bents, E.R.

    1995-05-01

    The end of the Cold War in the late 1980s resulted in a gigantic downsizing and consolidation of America`s defense industries, as domestic demand plummeted and the volume of international arms trading fell. However, in total world arms exports the United States exports more arms than any other nation. The country of Saudi Arabia has been the destination of a disproportionate amount of these weapons. The following account is an examination of the US military aerospace industry, the world military aerospace market, US government policy concerning arms exports, and the Saudi aerospace market. Each of these entities profoundly impacts US-Saudi military aerospace commerce. By individually analyzing the above factors, it will be demonstrated that the supply relationship between the US and Saudi Arabia is dependent on the convergence of several long standing and deep seated aspirations on the part of the three major players: the US Aerospace Industry, the US Government, and the Saudi Government. The US military aerospace industry`s exports are critical to ensure its independent survival, help fund crucial RD programs, and maintain a viable defense high tech industrial base in the U.S. In addition, it wishes to exert a military presence in the Gulf area and nurture relations with Saudi Arabia in particular, as the world`s leading oil producer. The Saudi government requires a military defense anchored in high tech aerospace systems, as well as a dependable and capable military ally such as the US.

  6. Thermal expansion anomaly regulated by entropy.

    PubMed

    Liu, Zi-Kui; Wang, Yi; Shang, ShunLi

    2014-01-01

    Thermal expansion, defined as the temperature dependence of volume under constant pressure, is a common phenomenon in nature and originates from anharmonic lattice dynamics. However, it has been poorly understood how thermal expansion can show anomalies such as colossal positive, zero, or negative thermal expansion (CPTE, ZTE, or NTE), especially in quantitative terms. Here we show that changes in configurational entropy due to metastable micro(scopic)states can lead to quantitative prediction of these anomalies. We integrate the Maxwell relation, statistic mechanics, and first-principles calculations to demonstrate that when the entropy is increased by pressure, NTE occurs such as in Invar alloy (Fe3Pt, for example), silicon, ice, and water, and when the entropy is decreased dramatically by pressure, CPTE is expected such as in anti-Invar cerium, ice and water. Our findings provide a theoretic framework to understand and predict a broad range of anomalies in nature in addition to thermal expansion, which may include gigantic electrocaloric and electromechanical responses, anomalously reduced thermal conductivity, and spin distributions. PMID:25391631

  7. Metal enrichment in the Fermi bubbles as a probe of their origin

    NASA Astrophysics Data System (ADS)

    Inoue, Yoshiyuki; Nakashima, Shinya; Tahara, Masaya; Kataoka, Jun; Totani, Tomonori; Fujita, Yutaka; Sofue, Yoshiaki

    2015-06-01

    The Fermi bubbles are gigantic gamma-ray structures in our Galaxy. The physical origin of the bubbles is still under debate. The leading scenarios can be divided into two categories. One is nuclear star-forming activity similar to extragalactic starburst galaxies and the other is past active galactic nucleus (AGN)-like activity of the Galactic center supermassive black hole. In this letter, we propose that metal abundance measurements will provide an important clue to probe their origin. Based on a simple spherically symmetric bubble model, we find that the generated metallicity and abundance patterns of the bubbles' gas strongly depend on assumed star formation or AGN activities. Star formation scenarios predict higher metallicities and abundance ratios of [O/Fe] and [Ne/Fe] than AGN scenarios do because of supernovae ejecta. Furthermore, the resultant abundance depends on the gamma-ray emission process because different mass injection histories are required for the different gamma-ray emission processes due to the acceleration and cooling time scales of non-thermal particles. Future X-ray missions such as ASTRO-H and Athena will give a clue to probe the origin of the bubbles through abundance measurements with their high energy resolution instruments.

  8. Mutation Update: The Spectra of Nebulin Variants and Associated Myopathies

    PubMed Central

    Lehtokari, Vilma-Lotta; Kiiski, Kirsi; Sandaradura, Sarah A.; Laporte, Jocelyn; Repo, Pauliina; Frey, Jennifer A.; Donner, Kati; Marttila, Minttu; Saunders, Carol; Barth, Peter G.; den Dunnen, Johan T.; Beggs, Alan H.; Clarke, Nigel F.; North, Kathryn N.; Laing, Nigel G.; Romero, Norma B.; Winder, Thomas L.; Pelin, Katarina; Wallgren-Pettersson, Carina

    2015-01-01

    A mutation update on the nebulin gene (NEB) is necessary because of recent developments in analysis methodology, the identification of increasing numbers and novel types of variants, and a widening in the spectrum of clinical and histological phenotypes associated with this gigantic, 183 exons containing gene. Recessive pathogenic variants in NEB are the major cause of nemaline myopathy (NM), one of the most common congenital myopathies. Moreover, pathogenic NEB variants have been identified in core-rod myopathy and in distal myopathies. In this update, we present the disease-causing variants in NEB in 159 families, 143 families with NM, and 16 families with NM-related myopathies. Eighty-eight families are presented here for the first time. We summarize 86 previously published and 126 unpublished variants identified in NEB. Furthermore, we have analyzed the NEB variants deposited in the Exome Variant Server (http://evs.gs.washington.edu/EVS/), identifying that pathogenic variants are a minor fraction of all coding variants (~7%). This indicates that nebulin tolerates substantial changes in its amino acid sequence, providing an explanation as to why variants in such a large gene result in relatively rare disorders. Lastly, we discuss the difficulties of drawing reliable genotype–phenotype correlations in NEB-associated disease. PMID:25205138

  9. The Revival of White Holes as Small Bangs

    E-print Network

    Alon Retter; Shlomo Heller

    2011-07-17

    Black holes are extremely dense and compact objects from which light cannot escape. There is an overall consensus that black holes exist and many astronomical objects are identified with black holes. White holes were understood as the exact time reversal of black holes, therefore they should continuously throw away material. It is accepted, however, that a persistent ejection of mass leads to gravitational pressure, the formation of a black hole and thus to the "death of while holes". So far, no astronomical source has been successfully tagged a white hole. The only known white hole is the Big Bang which was instantaneous rather than continuous or long-lasting. We thus suggest that the emergence of a white hole, which we name a 'Small Bang', is spontaneous - all the matter is ejected at a single pulse. Unlike black holes, white holes cannot be continuously observed rather their effect can only be detected around the event itself. Gamma ray bursts are the most energetic explosions in the universe. Long gamma-ray bursts were connected with supernova eruptions. There is a new group of gamma-ray bursts, which are relatively close to Earth, but surprisingly lack any supernova emission. We propose identifying these bursts with white holes. White holes seem like the best explanation of gamma-ray bursts that appear in voids. We also predict the detection of rare gigantic gamma-ray bursts with energies much higher than typically observed.

  10. Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly

    PubMed Central

    Martín-Rodríguez, Juan F.; Muñoz-Bravo, Jose L.; Ibañez-Costa, Alejandro; Fernandez-Maza, Laura; Balcerzyk, Marcin; Leal-Campanario, Rocío; Luque, Raúl M.; Castaño, Justo P.; Venegas-Moreno, Eva; Soto-Moreno, Alfonso; Leal-Cerro, Alfonso; Cano, David A.

    2015-01-01

    Acromegaly is a disorder resulting from excessive production of growth hormone (GH) and consequent increase of insulin-like growth factor 1 (IGF-I), most frequently caused by pituitary adenomas. Elevated GH and IGF-I levels results in wide range of somatic, cardiovascular, endocrine, metabolic, and gastrointestinal morbidities. Subcutaneous implantation of the GH-secreting GC cell line in rats leads to the formation of tumors. GC tumor-bearing rats develop characteristics that resemble human acromegaly including gigantism and visceromegaly. However, GC tumors remain poorly characterized at a molecular level. In the present work, we report a detailed histological and molecular characterization of GC tumors using immunohistochemistry, molecular biology and imaging techniques. GC tumors display histopathological and molecular features of human GH-producing tumors, including hormone production, cell architecture, senescence activation and alterations in cell cycle gene expression. Furthermore, GC tumors cells displayed sensitivity to somatostatin analogues, drugs that are currently used in the treatment of human GH-producing adenomas, thus supporting the GC tumor model as a translational tool to evaluate therapeutic agents. The information obtained would help to maximize the usefulness of the GC rat model for research and preclinical studies in GH-secreting tumors. PMID:26549306

  11. Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax.

    PubMed

    Prasad, R; Zhadanov, A B; Sedkov, Y; Bullrich, F; Druck, T; Rallapalli, R; Yano, T; Alder, H; Croce, C M; Huebner, K; Mazo, A; Canaani, E

    1997-07-31

    The ALL-1 gene is involved in human acute leukemia through chromosome translocations or internal rearrangements. ALL-1 is the human homologue of Drosophila trithorax. The latter is a member of the trithorax group (trx-G) genes which together with the Polycomb group (Pc-G) genes act as positive and negative regulators, respectively, to determine the body structure of Drosophila. We have cloned a novel human gene, ALR, which encodes a gigantic 5262 amino acid long protein containing a SET domain, five PHD fingers, potential zinc fingers, and a very long run of glutamines interrupted by hydrophobic residues, mostly leucine. The SET motif, PDH fingers, zinc fingers and two other regions are most similar to domains of ALL-1 and TRX. The first two motifs are also found in other trx-G and Pc-G proteins. The ALR gene was mapped to chromosome band 12q12-13, adjacent to the VDR gene. This region is involved in duplications and translocations associated with cancer. The analysis of ALR expression showed that its approximately 18 kb long mRNA is expressed, like ALL-1, in most adult tissues, including a variety of hematopoietic cells, with the exception of the liver. Whole mount in situ hybridization to early mouse embryos indicates expression in multiple tissues. Based on similarities in structure and expression pattern, ALR is likely to play a similar role to ALL-1 and trx, although its target genes have yet to be identified. PMID:9247308

  12. Semiconductor electronics and the birth of the modern science of surfaces

    NASA Astrophysics Data System (ADS)

    Gatos, Harry C.

    1994-01-01

    Semiconductor surfaces were the launching platform for the solid state electronic revolution. The brilliant concept of surface states led directly to the discovery of the transistor in 1947. The chemical instability of the Ge surfaces, however, rendered the new devices irreproducible and unstable. This threat to the viability of semiconductor electronics, precipitated an international search, of a magnitude unparalleled in the history of science and technology, directed at the understanding and controlling of semiconductor surfaces. The roots of all of today's powerful experimental tools, techniques, procedures and fundamental concepts at the disposal of surface science and engineering can be traced to that gigantic effort on the study of semiconductor surfaces. Clearly, solid state electronics, born and nurtured on semiconductor surfaces, gave, in turn, birth to the modern science of all surfaces. In this article, I attempt to convey a general impression of the mutually constructive interplay between the evolution of solid state electronics on the one hand and surface science and engineering on the other. I take this opportunity to highlight my own experiences and research involvement with semiconductor surfaces.

  13. New Indivisible Planetary Science Paradigm

    E-print Network

    J. Marvin Herndon

    2013-06-17

    I present here a new, indivisible planetary science paradigm, a wholly self-consistent vision of the nature of matter in the Solar System, and dynamics and energy sources of planets. Massive-core planets formed by condensing and raining-out from within giant gaseous protoplanets at high pressures and high temperatures. Earth's complete condensation included a 300 Earth-mass gigantic gas/ice shell that compressed the rocky kernel to about 66% of Earth's present diameter. T-Tauri eruptions stripped the gases away from the inner planets and stripped a portion of Mercury's incompletely condensed protoplanet, and transported it to the region between Mars and Jupiter where it fused with in-falling oxidized condensate from the outer regions of the Solar System and formed the parent matter of ordinary chondrite meteorites, the main-Belt asteroids, and veneer for the inner planets, especially Mars. In response to decompression-driven planetary volume increases, cracks form to increase surface area and mountain ranges characterized by folding form to accommodate changes in curvature. The differences between the inner planets are primarily the consequence of different degrees of protoplanetary compression. The internal composition of Mercury is calculated by analogy with the Earth. The rationale is provided for Mars potentially having a greater subsurface water reservoir capacity than before realized.

  14. Ultrafast Critical Nematic Fluctuations and Giant Magnetoelastic Coupling in Iron Pnictide

    NASA Astrophysics Data System (ADS)

    Patz, Aaron; Li, Tianqi; Ran, Sheng; Fernandes, Rafael; Schmalian, Joerg; Bud'Ko, Sergey; Canfield, Paul; Perakis, Ilias; Wang, Jigang

    2014-03-01

    A ubiquitous anisotropy in the normal state properties of many of the iron pnictides presents a crosscutting challenge important for understanding quantum magnetism and high-temperature superconductivity. Although an electronically-driven nematicity has been invoked, distinguishing this from spin and structural orders is challenging because they all couple together to break the same tetragonal symmetry. Here we use femtosecond-resolved polarimetry to reveal critical fluctuations of nematic correlation in unstrained Ba(Fe1-xCox)2As2. The ultrafast anisotropic response, which arises from the two-fold in-plane anisotropy of the refractive index, displays a characteristic two-step recovery absent in the isotropic response. The fast recovery appears only in the magnetically ordered state, whereas the slow one persists in the paramagnetic phase, with increasing relaxation time, indicative of critical nematic fluctuations approaching the structural transition temperature. The dynamics reveal a gigantic magnetoelastic coupling that far exceeds electron-spin and electron-phonon couplings, opposite to conventional magnetic metals. Supported by the NSF and THALES program NANOPHOS.

  15. The Interstellar Medium in the Small Magellanic Cloud: Results from MCELS

    NASA Astrophysics Data System (ADS)

    Winkler, P. F.; Smith, R. C.; Points, S. D.; MCELS Team

    2015-05-01

    The interstellar medium (ISM) provides the playing field where gas and dust are cycled into and out of stars through dynamic and complex interactions, including H II regions, planetary nebulae, supernovae and their remnants, superbubbles, and gigantic supershells. The relative proximity and low extinction make the Large and Small Magellanic Clouds ideal venues for studying the ISM: its constituents, energetics, and interaction with the underlying stellar populations. The Magellanic Cloud Emission Line Survey (MCELS) surveyed both the LMC and SMC over six years using the Curtis Schmidt Telescope at CTIO to produce deep images in H?, [S II] and [O III] lines, plus matched red and green continuum bands for star subtraction. The survey covers the central 8×8 degrees of the LMC and 4.5× 3.5 degrees of the SMC—most of the gaseous extent of both galaxies—at a resolution of 5? or better. This enables us to identify and study structures on scales ranging from 1 pc to global. In this paper we highlight some of the results from MCELS, concentrating on the SMC. These include deep inventories of PNe and SNRs, analysis of H II regions and their optical depth, and extended structures on the scale of the entire galaxy. We also include some brief historical anecdotes.

  16. Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint.

    PubMed

    Mossaid, Ikram; Fahrenkrog, Birthe

    2015-01-01

    The segregation of the chromosomes during mitosis is an important process, in which the replicated DNA content is properly allocated into two daughter cells. To ensure their genomic integrity, cells present an essential surveillance mechanism known as the spindle assembly checkpoint (SAC), which monitors the bipolar attachment of the mitotic spindle to chromosomes to prevent errors that would result in chromosome mis-segregation and aneuploidy. Multiple components of the nuclear pore complex (NPC), a gigantic protein complex that forms a channel through the nuclear envelope to allow nucleocytoplasmic exchange of macromolecules, were shown to be critical for faithful cell division and implicated in the regulation of different steps of the mitotic process, including kinetochore and spindle assembly as well as the SAC. In this review, we will describe current knowledge about the interconnection between the NPC and the SAC in an evolutional perspective, which primarily relies on the two mitotic checkpoint regulators, Mad1 and Mad2. We will further discuss the role of NPC constituents, the nucleoporins, in kinetochore and spindle assembly and the formation of the mitotic checkpoint complex during mitosis and interphase. PMID:26540075

  17. Land subsidence of clay deposits after the Tohoku-Pacific Ocean Earthquake

    NASA Astrophysics Data System (ADS)

    Yasuhara, K.; Kazama, M.

    2015-11-01

    Extensive infrastructure collapse resulted from the cataclysmic earthquake that struck off the eastern coast of Japan on 11 March 2011 and from its consequent gigantic tsunami, affecting not only the Tohoku region but also the Kanto region. Among the geological and geotechnical processes observed, land subsidence occurring in both coastal and inland areas and from Tohoku to Kanto is an extremely important issue that must be examined carefully. This land subsidence is classifiable into three categories: (i) land sinking along the coastal areas because of tectonic movements, (ii) settlement of sandy deposits followed by liquefaction, and (iii) long-term post-earthquake recompression settlement in soft clay caused by dissipation of excess pore pressure. This paper describes two case histories of post-earthquake settlement of clay deposits from among the three categories of ground sinking and land subsidence because such settlement has been frequently overlooked in numerous earlier earthquakes. Particularly, an attempt is made to propose a methodology for predicting such settlement and for formulating remedial or responsive measures to mitigate damage from such settlement.

  18. [Gender in view].

    PubMed

    1998-03-01

    A manual recently published by Mexico¿s National System for Integral Development of the Family, ¿The gender perspective: a tool for constructing equity between men and women¿, is intended to put into practice the Cairo accords. The gender perspective has been applied in recent years to interpretation of the situation of women in past and present societies. Gender is not sex; it is the manner in which societies have symbolized and understood relations between men and women. The manual concludes that the main difference between the sexes beyond the obvious genital differences is in the greater musculature and strength of males. In contemporary societies, these attributes are less needed than technical knowledge and skills, which may be obtained by either sex. Economic evolution has led increasing numbers of women to work outside their homes. The gender roles assigned for millennia, and accepted as the natural order, are no longer adequate. The power of men has been preserved by attributing the gigantic cultural differences resulting from specialization into male and female roles to the small physical differences between the sexes. Governments have slowly established legal equity, but discrimination against women has not disappeared in the workplace, public offices, or any other social sphere, and their incorporation into the work force has left them with the double workday as they continue to perform the great bulk of domestic work. It is therefore necessary to seek equity as well as equality, understood as the creation of equivalent opportunities for men and women. PMID:12349308

  19. The effect of albumin fusion structure on the production and bioactivity of the somatostatin-28 fusion protein in Pichia pastoris.

    PubMed

    Ding, Yuedi; Fan, Jun; Li, Wenxin; Peng, Ying; Yang, Runlin; Deng, Lili; Fu, Qiang

    2014-06-01

    Somatostatin, a natural inhibitor of growth hormone (GH), and its analogs have been used in clinical settings for the treatment of acromegaly, gigantism, thyrotropinoma, and other carcinoid syndromes. However, natural somatostatin is limited for clinical usage because of its short half-life in vivo. Albumin fusion technology was used to construct long-acting fusion proteins and Pichia pastoris was used as an expression system. Three fusion proteins (SS28)(2)-HSA, (SS28)(3)-HSA, and HSA-(SS28)(2), were constructed with different fusion copies of somatostatin-28 and fusion orientations. The expression level of (SS28)(3)-HSA was much lower than (SS28)(2)-HSA and HSA-(SS28)(2) due to the additional fusion of the somatostatin-28 molecule. MALDI-TOF mass spectrometry revealed that severe degradation occurred in the fermentation process. Similar to the standard, somatostatin-14, all three fusion proteins were able to inhibit GH secretion in blood, with (SS28)(2)-HSA being the most effective one. A pharmacokinetics study showed that (SS28)(2)-HSA had a prolonged half-life of 2 h. These results showed that increasing the number of small protein copies fused to HSA may not be a suitable method for improving protein bioactivity. PMID:24752560

  20. Genetic characterization of four native Italian shepherd dog breeds and analysis of their relationship to cosmopolitan dog breeds using microsatellite markers.

    PubMed

    Bigi, D; Marelli, S P; Randi, E; Polli, M

    2015-12-01

    Very little research into genetic diversity of Italian native dog breeds has been carried out so far. In this study we aimed to estimate and compare the genetic diversity of four native Italian shepherd dog breeds: the Maremma, Bergamasco, Lupino del Gigante and Oropa shepherds. Therefore, some cosmopolitan dog breeds, which have been widely raised in Italy for a long time past, have also been considered to check possible influence of these dog populations on the Italian autochthonous breeds considered here. A total of 212 individuals, belonging to 10 different dog breeds, were sampled and genotyped using 18 autosomal microsatellite loci. We analyzed the genetic diversity of these breeds, within breed diversity, breed relationship and population structure. The 10 breeds considered in this study were clearly genetically differentiated from each other, regardless of current population sizes and the onset of separate breeding history. The level of genetic diversity explained 20% of the total genetic variation. The level of H E found here is in agreement with that found by other studies. The native Italian breeds showed generally higher genetic diversity compared with the long established, well-defined cosmopolitan dog breeds. As the Border Collie seems closer to the Italian breeds than the other cosmopolitan shepherd dogs considered here, a possible utilization of this breed to improve working performance in Italian traditional working shepherd dogs cannot be ignored. The data and information found here can be utilized in the organization of conservation programs planned to reduce inbreeding and to minimize loss of genetic variability. PMID:26245492

  1. A giant crocodile in the Dubois Collection from the Pleistocene of Kali Gedeh (Java).

    PubMed

    Delfino, Massimo; De Vos, John

    2014-03-01

    The fauna of the Pleistocene Homo-bearing sites of Java has been well known for more than a century. A recent revision of the crocodylian remains confirmed both the validity of Gavialis bengawanicus and the synonymization of Crocodylus ossifragus with C. siamensis. Here we report on a still unpublished crocodylian specimen collected by Eugene Dubois in the latest Early Pleistocene of Kali Gedeh that can be tentatively referred to the genus Crocodylus. The size of the specimen, the approximately 1 m long lower jaw in particular, indicated that this crocodile attained a total length of approximately 6 or 7 m. Along with specimens from the Plio-Pleistocene of Africa, this material provides evidence for gigantism in Crocodylus. It is not clear whether or not the 'temperature-size rule' applies to fossil crocodylians, but due to the growing interest in predicting future temperature-related size changes of the extant organisms, it would be interesting to study in detail the past reaction to temperature changes of crocodylians and other terrestrial ectothermic animals. PMID:24673759

  2. History of rocketry in India

    NASA Astrophysics Data System (ADS)

    Vasant, Gowarikar; Suresh, B. N.

    2009-12-01

    The Indian Space programme took birth on November 21, 1963, with the launch of Nike-Apache, an American sounding rocket from the shores of Thumba near Thiruvananthapuram on the west coast of India. From a family of operational sounding rockets known as the Rohini Sounding Rockets, India's launch vehicles have now grown up through SLV-3 and Augmented Satellite Launch Vehicle (ASLV) to the current gigantic satellite launchers, PSLV and Geosynchronous Satellite Launch Vehicle (GSLV). Though we had failures in the initial launches of SLV-3, ASLV and PSLV, these failures gave Indian Space Research Organisation (ISRO) a thorough and in depth understanding of the nuances of launch vehicle technology that later led to successful missions. An entirely new dimension was added to the Indian space programme when a space capsule was recovered very precisely after it had orbited the Earth for 12 days. The future for launch vehicles in ISRO looks bright with the GSLV MKIII, which is currently under development and the pursuit of cutting edge technologies such as reusable launch vehicles and air-breathing propulsion.

  3. Genome Evolution by Matrix Algorithms: Cellular Automata Approach to Population Genetics

    PubMed Central

    Qiu, Shuhao; McSweeny, Andrew; Choulet, Samuel; Saha-Mandal, Arnab; Fedorova, Larisa; Fedorov, Alexei

    2014-01-01

    Mammalian genomes are replete with millions of polymorphic sites, among which those genetic variants that are colocated on the same chromosome and exist close to one another form blocks of closely linked mutations known as haplotypes. The linkage within haplotypes is constantly disrupted due to meiotic recombination events. Whole ensembles of such numerous haplotypes are subjected to evolutionary pressure, where mutations influence each other and should be considered as a whole entity—a gigantic matrix, unique for each individual genome. This idea was implemented into a computational approach, named Genome Evolution by Matrix Algorithms (GEMA) to model genomic changes taking into account all mutations in a population. GEMA has been tested for modeling of entire human chromosomes. The program can precisely mimic real biological processes that have influence on genome evolution such as: 1) Authentic arrangements of genes and functional genomic elements, 2) frequencies of various types of mutations in different nucleotide contexts, and 3) nonrandom distribution of meiotic recombination events along chromosomes. Computer modeling with GEMA has demonstrated that the number of meiotic recombination events per gamete is among the most crucial factors influencing population fitness. In humans, these recombinations create a gamete genome consisting on an average of 48 pieces of corresponding parental chromosomes. Such highly mosaic gamete structure allows preserving fitness of population under the intense influx of novel mutations (40 per individual) even when the number of mutations with deleterious effects is up to ten times more abundant than those with beneficial effects. PMID:24723728

  4. 3D reconstruction of the source and scale of buried young flood channels on Mars.

    PubMed

    Morgan, Gareth A; Campbell, Bruce A; Carter, Lynn M; Plaut, Jeffrey J; Phillips, Roger J

    2013-05-01

    Outflow channels on Mars are interpreted as the product of gigantic floods due to the catastrophic eruption of groundwater that may also have initiated episodes of climate change. Marte Vallis, the largest of the young martian outflow channels (<500 million years old), is embayed by lava flows that hinder detailed studies and comparisons with older channel systems. Understanding Marte Vallis is essential to our assessment of recent Mars hydrologic activity during a period otherwise considered to be cold and dry. Using data from the Shallow Radar sounder on the Mars Reconnaissance Orbiter, we present a three-dimensional (3D) reconstruction of buried channels on Mars and provide estimates of paleohydrologic parameters. Our work shows that Cerberus Fossae provided the waters that carved Marte Vallis, and it extended an additional 180 kilometers to the east before the emplacement of the younger lava flows. We identified two stages of channel incision and determined that channel depths were more than twice those of previous estimates. PMID:23470730

  5. When did Carcharocles megalodon become extinct? A new analysis of the fossil record.

    PubMed

    Pimiento, Catalina; Clements, Christopher F

    2014-01-01

    Carcharocles megalodon ("Megalodon") is the largest shark that ever lived. Based on its distribution, dental morphology, and associated fauna, it has been suggested that this species was a cosmopolitan apex predator that fed on marine mammals from the middle Miocene to the Pliocene (15.9-2.6 Ma). Prevailing theory suggests that the extinction of apex predators affects ecosystem dynamics. Accordingly, knowing the time of extinction of C. megalodon is a fundamental step towards understanding the effects of such an event in ancient communities. However, the time of extinction of this important species has never been quantitatively assessed. Here, we synthesize the most recent records of C. megalodon from the literature and scientific collections and infer the date of its extinction by making a novel use of the Optimal Linear Estimation (OLE) model. Our results suggest that C. megalodon went extinct around 2.6 Ma. Furthermore, when contrasting our results with known ecological and macroevolutionary trends in marine mammals, it became evident that the modern composition and function of modern gigantic filter-feeding whales was established after the extinction of C. megalodon. Consequently, the study of the time of extinction of C. megalodon provides the basis to improve our understanding of the responses of marine species to the removal of apex predators, presenting a deep-time perspective for the conservation of modern ecosystems. PMID:25338197

  6. Choosing Between Yeast and Bacterial Expression Systems: Yield Dependent

    NASA Technical Reports Server (NTRS)

    Miller, Rebecca S.; Malone, Christine C.; Moore, Blake P.; Burk, Melissa; Crawford, Lisa; Karr, Laurel J.; Curreri, Peter A. (Technical Monitor)

    2002-01-01

    Green fluorescent protein (GFP) is a naturally occurring fluorescent protein isolated from the jellyfish Aequorea victoria. The intrinsic fluorescence of the protein is due to a chromophore located in the center of the molecule. Its usefulness has been established as a marker for gene expression and localization of gene products. GFP has recently been utilized as a model protein for crystallization studies at NASA/MSFC, both in earth-based and in microgravity experiments. Because large quantities of purified protein were needed, the cDNA of GFP was cloned into the Pichia pastoris pPICZ(alpha) C strain, with very little protein secreted into the media. Microscopic analysis prior to harvest showed gigantic green fluorescent yeast, but upon harvesting most protein was degraded. Trial fermentations of GFP cloned into pPICZ A for intracellular expression provided unsatisfactory yield. GFP cloned into E, coli was overexpressed at greater than 150 mg/liter, with purification yields at greater than 100mg/liter.

  7. Cell size versus body size in geophilomorph centipedes.

    PubMed

    Moretto, Marco; Minelli, Alessandro; Fusco, Giuseppe

    2015-04-01

    Variation in animal body size is the result of a complex interplay between variation in cell number and cell size, but the latter has seldom been considered in wide-ranging comparative studies, although distinct patterns of variation have been described in the evolution of different lineages. We investigated the correlation between epidermal cell size and body size in a sample of 29 geophilomorph centipede species, representative of a wide range of body sizes, from 6 mm dwarf species to gigantic species more than 200 mm long, exploiting the marks of epidermal cells on the overlying cuticle in the form of micro-sculptures called scutes. We found conspicuous and significant variation in average scute area, both between suprageneric taxa and between genera, while the within-species range of variation is comparatively small. This supports the view that the average epidermal cell size is to some extent taxon specific. However, regression analyses show that neither body size nor the number of leg-bearing segments explain this variation, which suggests that cell size is not an usual target of change for body size evolution in this group of arthropods, although there is evidence of its correlation with other morphological variables, like cuticle thickness. Scute sizes of miniaturized geophilomorph species are well within the range of the lineage to which the species belong, suggesting recent evolutionary transitions to smaller body size. PMID:25809818

  8. Highly viscous liquid crystalline mixtures: the alternative to liquid crystalline elastomers

    NASA Astrophysics Data System (ADS)

    Shibaev, Petr; Schlesier, Cristina; Newman, Leah; McDonald, Scott

    2012-02-01

    Novel highly viscous liquid crystalline materials based on mixtures of glass forming oligomers and low molar mass liquid crystals were recently designed [1, 2] and studied. In this communication the novel data are presented, the analysis and discussion are extended. It is shown that viscoelastic properties of the materials are due to the physical entanglements between cyclic oligomers and low molar mass mesogens, not due to the chemical crosslinks between molecular moities. However, the mechanical properties of these viscoelastic materials resemble those of chemically crosslinked elastomers (elasticity and reversibility of deformations). The properties of chiral and non-chiral materials loaded with ferromagnetic nanoparticles are discussed in detail. Cholesteric materials undergo gigantic color changes in the wide spectral range under the deformation that allows distant detection of deformation and determination the anisotropy of deformation and its type. The materials doped with laser dyes become mechanically tunable lasers themselves and emit coherent light while pumped by external laser. A simple model is suggested to account for the observed effects; physical properties of the novel materials and liquid crystalline elastomers are compared and discussed. [4pt] [1] P.V. Shibaev, C. Schlesier, R. Uhrlass, S. Woodward, E. Hanelt, Liquid Crystals, 37:12, 1601-1604 [0pt] [2] P.V. Shibaev, P. Riverra, D. Teter, S. Marsico, M. Sanzari, V. Ramakrishnan, E. Hanelt, Optics Express, 16, 2965 (2008)

  9. Martian outflow channels: How did their source aquifers form, and why did they drain so rapidly?

    NASA Astrophysics Data System (ADS)

    Rodriguez, J. Alexis P.; Kargel, Jeffrey S.; Baker, Victor R.; Gulick, Virginia C.; Berman, Daniel C.; Fairén, Alberto G.; Linares, Rogelio; Zarroca, Mario; Yan, Jianguo; Miyamoto, Hideaki; Glines, Natalie

    2015-09-01

    Catastrophic floods generated ~3.2 Ga by rapid groundwater evacuation scoured the Solar System’s most voluminous channels, the southern circum-Chryse outflow channels. Based on Viking Orbiter data analysis, it was hypothesized that these outflows emanated from a global Hesperian cryosphere-confined aquifer that was infused by south polar meltwater infiltration into the planet’s upper crust. In this model, the outflow channels formed along zones of superlithostatic pressure generated by pronounced elevation differences around the Highland-Lowland Dichotomy Boundary. However, the restricted geographic location of the channels indicates that these conditions were not uniform Boundary. Furthermore, some outflow channel sources are too high to have been fed by south polar basal melting. Using more recent mission data, we argue that during the Late Noachian fluvial and glacial sediments were deposited into a clastic wedge within a paleo-basin located in the southern circum-Chryse region, which was then completely submerged under a primordial northern plains ocean. Subsequent Late Hesperian outflow channels were sourced from within these geologic materials and formed by gigantic groundwater outbursts driven by an elevated hydraulic head from the Valles Marineris region. Thus, our findings link the formation of the southern circum-Chryse outflow channels to ancient marine, glacial, and fluvial erosion and sedimentation.

  10. Interplay between superconductivity and magnetism in Fe1?xPdxTe

    PubMed Central

    Karki, Amar B.; Garlea, V. Ovidiu; Custelcean, Radu; Stadler, Shane; Plummer, E. W.; Jin, Rongying

    2013-01-01

    The attractive/repulsive relationship between superconductivity and magnetic ordering has fascinated the condensed matter physics community for a century. In the early days, magnetic impurities doped into a superconductor were found to quickly suppress superconductivity. Later, a variety of systems, such as cuprates, heavy fermions, and Fe pnictides, showed superconductivity in a narrow region near the border to antiferromagnetism (AFM) as a function of pressure or doping. However, the coexistence of superconductivity and ferromagnetic (FM) or AFM ordering is found in a few compounds [RRh4B4 (R = Nd, Sm, Tm, Er), R?Mo6X8 (R? = Tb, Dy, Er, Ho, and X = S, Se), UMGe (M = Ge, Rh, Co), CeCoIn5, EuFe2(As1?xPx)2, etc.], providing evidence for their compatibility. Here, we present a third situation, where superconductivity coexists with FM and near the border of AFM in Fe1?xPdxTe. The doping of Pd for Fe gradually suppresses the first-order AFM ordering at temperature TN/S, and turns into short-range AFM correlation with a characteristic peak in magnetic susceptibility at T?N. Superconductivity sets in when T?N reaches zero. However, there is a gigantic ferromagnetic dome imposed in the superconducting-AFM (short-range) cross-over regime. Such a system is ideal for studying the interplay between superconductivity and two types of magnetic (FM and AFM) interactions. PMID:23690601

  11. What big eyes you have: the ecological role of giant pterygotid eurypterids

    PubMed Central

    Anderson, Ross P.; McCoy, Victoria E.; McNamara, Maria E.; Briggs, Derek E. G.

    2014-01-01

    Eurypterids are a group of extinct chelicerates that ranged for over 200 Myr from the Ordovician to the Permian. Gigantism is common in the group; about 50% of families include taxa over 0.8 m in length. Among these were the pterygotids (Pterygotidae), which reached lengths of over 2 m and were the largest arthropods that ever lived. They have been interpreted as highly mobile visual predators on the basis of their large size, enlarged, robust chelicerae and forward-facing compound eyes. Here, we test this interpretation by reconstructing the visual capability of Acutiramus cummingsi (Pterygotidae) and comparing it with that of the smaller Eurypterus sp. (Eurypteridae), which lacked enlarged chelicerae, and other arthropods of similar geologic age. In A. cummingsi, there is no area of lenses differentiated to provide increased visual acuity, and the interommatidial angles (IOA) do not fall within the range of high-level modern arthropod predators. Our results show that the visual acuity of A. cummingsi is poor compared with that of co-occurring Eurypterus sp. The ecological role of pterygotids may have been as predators on thin-shelled and soft-bodied prey, perhaps in low-light conditions or at night. PMID:25009243

  12. Rb-Sr, Sm-Nd, K-Ca, O, and H isotopic study of Cretaceous-Tertiary boundary sediments, Caravaca, Spain Evidence for an oceanic impact site

    NASA Technical Reports Server (NTRS)

    Depaolo, D. J.; Kyte, F. T.; Marshall, B. D.; Oneil, J. R.; Smit, J.

    1983-01-01

    The results of isotopic and trace-element-abundance analyses of Ir-enriched Cretaceous-Tertiary-boundary clay sediments from Caravaca, Spain, and of adjacent carbonate and marl layers, are presented. Acetic-acid and HCl leachates and residues were analyzed by isotope dilution to determine K, Rb, Sr, Sm, and Nd concentrations and Sr-87/Sr-86 and Nd-143/Nd-144 ratios. The stable isotope ratios delta-D, delta-(C-13), and delta-(0-18) were also determined. The results are presented in tables and graphs and compared with published data on the Caravaca sediments and on samples from other locations. The boundary clay is found to be distinguished from the adjacent layers by its isotopic ratios and to be of mainly terrestrial, lithospheric (deeper than 3-km) origin. Although submarine-weathering effects are evident and difficult to quantify, the degree of variation in Ni, Ir, Sr, and REE concentrations is considered too large to be attributed to postdepositional processes alone. These findings are seen as evidence for the ocean impact of a large single asteroid producing a worldwide blanket of ejecta, a large injection of water vapor into the atmosphere, and perhaps a gigantic tsunami, at the end of the Cretaceous period.

  13. D.O.T. requirements for transportation of sample containers

    SciTech Connect

    Welker, T.F.

    1995-12-01

    During my travels around the United States talking about sampling and sample containers, it has come to my attention that the oil and gas industry in the U.S. needs to be a little better informed on proper handling, shipping and transportation of sample containers of all types. Since everybody in the oil, gas and chemical industry seems to be involved in taking samples and handling sample containers, it behooves us to understand the laws and rules that govern their transportation. The Department of Transportation (D.O.T.) Title 49 covers the rules and regulations for the manufacture, handling and transportation of sample containers of all types. Whether you use specially-built sample containers, old homemade sample containers, old World War II oxygen bottles, gigantic sample containers, or very small cylinders, if you are transporting those sample containers in your vehicles or you are shipping them by common carrier and they have hazardous materials in them, you must be aware of the rules that govern the handling of those cylinders.

  14. Parasitism and phenotypic change in colonial hosts.

    PubMed

    Hartikainen, Hanna; Fontes, Inês; Okamura, Beth

    2013-09-01

    Changes in host phenotype are often attributed to manipulation that enables parasites to complete trophic transmission cycles. We characterized changes in host phenotype in a colonial host–endoparasite system that lacks trophic transmission (the freshwater bryozoan Fredericella sultana and myxozoan parasite Tetracapsuloides bryosalmonae). We show that parasitism exerts opposing phenotypic effects at the colony and module levels. Thus, overt infection (the development of infectious spores in the host body cavity) was linked to a reduction in colony size and growth rate, while colony modules exhibited a form of gigantism. Larger modules may support larger parasite sacs and increase metabolite availability to the parasite. Host metabolic rates were lower in overtly infected relative to uninfected hosts that were not investing in propagule production. This suggests a role for direct resource competition and active parasite manipulation (castration) in driving the expression of the infected phenotype. The malformed offspring (statoblasts) of infected colonies had greatly reduced hatching success. Coupled with the severe reduction in statoblast production this suggests that vertical transmission is rare in overtly infected modules. We show that although the parasite can occasionally infect statoblasts during overt infections, no infections were detected in the surviving mature offspring, suggesting that during overt infections, horizontal transmission incurs a trade-off with vertical transmission. PMID:23965820

  15. Wafer-scale metasurface for total power absorption, local field enhancement and single molecule Raman spectroscopy

    PubMed Central

    Wang, Dongxing; Zhu, Wenqi; Best, Michael D.; Camden, Jon P.; Crozier, Kenneth B.

    2013-01-01

    The ability to detect molecules at low concentrations is highly desired for applications that range from basic science to healthcare. Considerable interest also exists for ultrathin materials with high optical absorption, e.g. for microbolometers and thermal emitters. Metal nanostructures present opportunities to achieve both purposes. Metal nanoparticles can generate gigantic field enhancements, sufficient for the Raman spectroscopy of single molecules. Thin layers containing metal nanostructures (“metasurfaces”) can achieve near-total power absorption at visible and near-infrared wavelengths. Thus far, however, both aims (i.e. single molecule Raman and total power absorption) have only been achieved using metal nanostructures produced by techniques (high resolution lithography or colloidal synthesis) that are complex and/or difficult to implement over large areas. Here, we demonstrate a metasurface that achieves the near-perfect absorption of visible-wavelength light and enables the Raman spectroscopy of single molecules. Our metasurface is fabricated using thin film depositions, and is of unprecedented (wafer-scale) extent. PMID:24091825

  16. Linquistic geometry: new technology for decision support

    NASA Astrophysics Data System (ADS)

    Stilman, Boris; Yakhnis, Vladimir

    2003-09-01

    Linguistic Geometry (LG) is a revolutionary gaming approach which is ideally suited for military decision aids for Air, Ground, Naval, and Space-based operations, as well guiding robotic vehicles and traditional entertainment games. When thinking about modern or future military operations, the game metaphor comes to mind right away. Indeed, the air space together with the ground and seas may be viewed as a gigantic three-dimensional game board. Refining this picture, the LG approach is capable of providing an LG hypergame, that is, a system of multiple concurrent interconnected multi-player abstract board games (ABG) of various resolutions and time frames reflecting various kinds of hardware and effects involved in the battlespace and the solution space. By providing a hypergame representation of the battlespace, LG already provides a significant advance in situational awareness. However, the greatest advantage of the LG approach is an ability to provide commanders of campaigns and missions with decision options resulting in attainment of the commander's intent. At each game turn, an LG decision support tool assigns the best actions to each of the multitude of battlespace actors (UAVs, bombers, cruise missiles, etc.). This is done through utilization of algorithms finding winning strategies and tactics, which are the core of the LG approach.

  17. The Magellanic Stream System: I. Ram-pressure tails and the relics of the collision between the Magellanic Clouds

    E-print Network

    Hammer, F; Flores, H; Puech, M; Fouquet, S

    2015-01-01

    We have analyzed the Magellanic Stream (MS) using the deepest and the most resolved HI survey of the Southern Hemisphere (GASS). The overall Stream is structured into two filaments suggesting two ram-pressure tails lagging behind the Magellanic Clouds (MCs), and resembling two close, transonic, von Karman vortex streets. The past motions of the Clouds appear imprinted in them, implying almost parallel initial orbits, and then a radical change after their passage near the N(HI) peak of the MS. This is consistent with a recent collision between the MCs, 200-300 Myr ago, which has stripped further their gas into small clouds, spreading them out along a gigantic bow-shock, perpendicular to the MS. The Stream is formed by the interplay between stellar feedback and the ram-pressure exerted by Milky Way (MW) halo hot gas with $n_h$= $10^{-4}$ $cm^{-3}$ at 50-70 kpc, a value necessary for explaining the MS multiphase high-velocity clouds. The corresponding hydrodynamical modeling provides the currently most accurate ...

  18. ADELE sensitivity to high-energy radiation from transient luminous events during the Hurricane and Severe Storm Sentinels campaigns

    NASA Astrophysics Data System (ADS)

    Bowers, G.; Smith, D. M.; Dwyer, J. R.; Cummer, S. A.; Martinez-Mckinney, F.; Kelley, N. A.; Harris, C. B.; Buzbee, P.

    2012-12-01

    In the summers of 2013 and 2014, UCSC will fly the Airborne Detector for Energetic Lightning Emissions (ADELE) instrument on board one of the Global Hawk aircraft of the NASA Hurricane and Severe Storm Sentinels (HS3) campaign over storms in the Atlantic. In addition to Terrestrial Gamma-ray Flashes (TGFs), which have been observed at gamma-ray energies by satellites such as RHESSI and FERMI, ADELE will also search for high-energy radiation from Transient Luminous Events (TLEs, i.e. elves, gigantic jets, blue jets, sprites, and sprite halos). High-energy radiation is plausible as a byproduct of stepped leaders in jets, streamers in sprites, and acceleration of electrons in the electromagnetic pulse (EMP) that produces elves. Because ADELE will fly at low altitudes, the intensity of radiation from these events could be orders of magnitude higher at ADELE than at satellites in low earth orbit. We will consider the high energy spectra that might be produced by TLEs and estimate to what extent these phenomena can be observed by ADELE on HS3.

  19. A visualization framework for large-scale virtual astronomy

    NASA Astrophysics Data System (ADS)

    Fu, Chi-Wing

    Motivated by advances in modern positional astronomy, this research attempts to digitally model the entire Universe through computer graphics technology. Our first challenge is space itself. The gigantic size of the Universe makes it impossible to put everything into a typical graphics system at its own scale. The graphics rendering process can easily fail because of limited computational precision, The second challenge is that the enormous amount of data could slow down the graphics; we need clever techniques to speed up the rendering. Third, since the Universe is dominated by empty space, objects are widely separated; this makes navigation difficult. We attempt to tackle these problems through various techniques designed to extend and optimize the conventional graphics framework, including the following: power homogeneous coordinates for large-scale spatial representations, generalized large-scale spatial transformations, and rendering acceleration via environment caching and object disappearance criteria. Moreover, we implemented an assortment of techniques for modeling and rendering a variety of astronomical bodies, ranging from the Earth up to faraway galaxies, and attempted to visualize cosmological time; a method we call the Lightcone representation was introduced to visualize the whole space-time of the Universe at a single glance. In addition, several navigation models were developed to handle the large-scale navigation problem. Our final results include a collection of visualization tools, two educational animations appropriate for planetarium audiences, and state-of-the-art-advancing rendering techniques that can be transferred to practice in digital planetarium systems.

  20. Interplay between Superconductivity and Magnetism in Fe1-xPdxTe

    SciTech Connect

    Karki, A B; Garlea, Vasile O; Custelcean, Radu; Stadler, S.; Plummer, E. W.; Jin, Rongying

    2013-01-01

    The love/hate relationship between superconductivity and magnetic ordering has fascinated the condensed matter physics community for a century. In the early days, magnetic impurities doped into a superconductor were found to quickly suppress superconductivity. Later, a variety of systems, such as cuprates, heavy fermions and Fe pnictides, show superconductivity in a narrow region near the border to antiferromagnetism (AFM) as a function of pressure or doping. On the other hand, the coexistence of superconductivity and ferromagnetic (FM) or AFM ordering is found in a few compounds (RRh4B4 (R = Nd, Sm, Tm, Er), R'Mo6X8 (R' = Tb, Dy, Er, Ho, and X = S, Se), UMGe (M = Ge, Rh, Co), CeCoIn5, EuFe2(As1-xPx)2 etc.), providing evidence for their compatibility. Here, we present a third situation, where superconductivity coexists with FM and near the border of AFM in Fe1-xPdxTe. The doping of Pd for Fe gradually suppresses the first-order AFM ordering at temperature TN/S, and turns into short-range (SR) AFM correlation with a characteristic peak in magnetic susceptibility at T'N. Superconductivity sets in when T'N reaches zero. However, there is a gigantic ferromagnetic dome imposed in the superconducting-AFM (SR) crossover regime. Such a system is ideal for studying the interplay between superconductivity and two types of magnetic interactions (FM and AFM).

  1. No evidence for directional evolution of body mass in herbivorous theropod dinosaurs.

    PubMed

    Zanno, Lindsay E; Makovicky, Peter J

    2013-01-22

    The correlation between large body size and digestive efficiency has been hypothesized to have driven trends of increasing mass in herbivorous clades by means of directional selection. Yet, to date, few studies have investigated this relationship from a phylogenetic perspective, and none, to our knowledge, with regard to trophic shifts. Here, we reconstruct body mass in the three major subclades of non-avian theropod dinosaurs whose ecomorphology is correlated with extrinsic evidence of at least facultative herbivory in the fossil record--all of which also achieve relative gigantism (more than 3000 kg). Ordinary least-squares regressions on natural log-transformed mean mass recover significant correlations between increasing mass and geological time. However, tests for directional evolution in body mass find no support for a phylogenetic trend, instead favouring passive models of trait evolution. Cross-correlation of sympatric taxa from five localities in Asia reveals that environmental influences such as differential habitat sampling and/or taphonomic filtering affect the preserved record of dinosaurian body mass in the Cretaceous. Our results are congruent with studies documenting that behavioural and/or ecological factors may mitigate the benefit of increasing mass in extant taxa, and suggest that the hypothesis can be extrapolated to herbivorous lineages across geological time scales. PMID:23193135

  2. Martian outflow channels: How did their source aquifers form, and why did they drain so rapidly?

    PubMed

    Rodriguez, J Alexis P; Kargel, Jeffrey S; Baker, Victor R; Gulick, Virginia C; Berman, Daniel C; Fairén, Alberto G; Linares, Rogelio; Zarroca, Mario; Yan, Jianguo; Miyamoto, Hideaki; Glines, Natalie

    2015-01-01

    Catastrophic floods generated ~3.2 Ga by rapid groundwater evacuation scoured the Solar System's most voluminous channels, the southern circum-Chryse outflow channels. Based on Viking Orbiter data analysis, it was hypothesized that these outflows emanated from a global Hesperian cryosphere-confined aquifer that was infused by south polar meltwater infiltration into the planet's upper crust. In this model, the outflow channels formed along zones of superlithostatic pressure generated by pronounced elevation differences around the Highland-Lowland Dichotomy Boundary. However, the restricted geographic location of the channels indicates that these conditions were not uniform Boundary. Furthermore, some outflow channel sources are too high to have been fed by south polar basal melting. Using more recent mission data, we argue that during the Late Noachian fluvial and glacial sediments were deposited into a clastic wedge within a paleo-basin located in the southern circum-Chryse region, which was then completely submerged under a primordial northern plains ocean. Subsequent Late Hesperian outflow channels were sourced from within these geologic materials and formed by gigantic groundwater outbursts driven by an elevated hydraulic head from the Valles Marineris region. Thus, our findings link the formation of the southern circum-Chryse outflow channels to ancient marine, glacial, and fluvial erosion and sedimentation. PMID:26346067

  3. Energy and globalization

    NASA Astrophysics Data System (ADS)

    Birjandi, Hossein Saremi

    Before the Industrial Revolution, nations required no energy fuel. People relied on human, animal, and wind and waterpower for energy need. Energy (oil) has resettled populations, elected officials in the free world, or changed the governments of the energy rich countries by force. Energy fueled wars, played the major factor in the might of those who have it or more importantly the abilities to acquire it by force. This dissertation researches the primacy of oil as an energy source from the time of oil's discovery to the present times. Between 1945 and 1960, the use of oil and gas doubled as power was generated for industries as steel, cement, metalworking and more important of all filling station hoses into automobiles gas tanks, thus energy swept people and societies quite literally off their feet. One in every six jobs in the industrial world hired by the giant automotive industries. The big five American oil companies spurred on by special tax benefit, these companies grew to gigantic sizes by taking out the best part of the nation's oil. Then, for greater growth, they leaped overseas and built up an immensely profitable system, in alliance with Anglo-Dutch Shell and British Petroleum, known as seven sisters. On the other side of the world, the energy producing nations form an alliance mainly to protect themselves from downward price fluctuations of oil. The struggle for survival in the global energy market forced those countries to get together and form OPEC, which is referred as an "oil cartel".

  4. Northwestern Tharsis Latent Outflow Activity Mars

    NASA Technical Reports Server (NTRS)

    Dohm, J. M.; Anderson, R. C.; Baker, V. R.; Ferris, J. C.; Hare, T. M.; Strom, R. G.; Rudd, L.; Rice, J. W., Jr.; Scott, D. H.

    2000-01-01

    Previously defined outflow channels, which are indicated by relict landforms similar to those observed on Earth, signify ancient catastrophic flood events on Mars. These conspicuous geomorphic features are some of the most remarkable yet profound discoveries made by geologists to date. These outflow channels, which debouched tremendous volumes of water into topographic lows such as Chryse, Utopia, Elysium, and Hellas Planitiae, may represent the beginning of warmer and wetter climatic periods unlike the present-day cold and dry Mars. In addition to the previously identified outflow channels, observations permitted by the newly acquired Mars Orbiter Laser Altimeter (MOLA) data have revealed a system of gigantic valleys, referred to as the northwestern slope valleys (NSV), that are located to the northwest of a huge shield volcano, Arsia Mons, western hemisphere of Mars. These features generally correspond spatially to gravity lows similar to the easternmost, circum-Chryse outflow channel systems. Geologic investigations of the Tharsis region suggest that the large valley system pre-dates the construction of Arsia Mons and its extensive associated lava flows of mainly Late Hesperian and Amazonian age and coincides stratigraphically with the early development of the circum-Chryse outflow channel systems that debouch into Chryse Planitia. This newly identified system, the NSV, potentially signifies the largest flood event(s) ever recorded for the solar system. Additional information is contained in original extended abstract.

  5. The potential of THEMIS satellite and ground-based measurements for data mining

    NASA Astrophysics Data System (ADS)

    Frey, S.; Angelopoulos, V.; Sibeck, D. G.; Phan, T.; Eastwood, J. P.; Runov, A.; Frey, H. U.

    2009-12-01

    Launched on February 17, 2007 on a DELTA II rocket, NASA's Time History of Events and Macroscale Interactions during Substorms (THEMIS) mission is a Medium-class Explorer project and the first space mission to study the sequence of magnetospheric events that trigger gigantic auroral displays in the polar regions using a macro-scale constellation of spacecraft. THEMIS is composed of a space segment of 5 identical probes equipped with particle and field instruments and a ground segment of about 20 Ground-Based Observatories with all-sky cameras and magnetometers. During its nominal mission THEMIS has observed over 20 substorm events, measured radial profiles of high energy particles through the radiation belts year-round, and provided numerous multi-point measurements across the magnetopause and bow shock with upstream monitoring. THEMIS data as well as the methods developed to simultaneously detect magnetospheric processes or structures are ideal for the development of software tools to efficiently extract data. We will present the potential of the THEMIS data to catalog magnetospheric events, define search patterns for event detection as well standardized interfaces with models.

  6. Atmospheric oxygen, giant Paleozoic insects and the evolution of aerial locomotor performance.

    PubMed

    Dudley, R

    1998-04-01

    Uniformitarian approaches to the evolution of terrestrial locomotor physiology and animal flight performance have generally presupposed the constancy of atmospheric composition. Recent geophysical data as well as theoretical models suggest that, to the contrary, both oxygen and carbon dioxide concentrations have changed dramatically during defining periods of metazoan evolution. Hyperoxia in the late Paleozoic atmosphere may have physiologically enhanced the initial evolution of tetrapod locomotor energetics; a concurrently hyperdense atmosphere would have augmented aerodynamic force production in early flying insects. Multiple historical origins of vertebrate flight also correlate temporally with geological periods of increased oxygen concentration and atmospheric density. Arthropod as well as amphibian gigantism appear to have been facilitated by a hyperoxic Carboniferous atmosphere and were subsequently eliminated by a late Permian transition to hypoxia. For extant organisms, the transient, chronic and ontogenetic effects of exposure to hyperoxic gas mixtures are poorly understood relative to contemporary understanding of the physiology of oxygen deprivation. Experimentally, the biomechanical and physiological effects of hyperoxia on animal flight performance can be decoupled through the use of gas mixtures that vary in density and oxygen concentration. Such manipulations permit both paleophysiological simulation of ancestral locomotor performance and an analysis of maximal flight capacity in extant forms. PMID:9510518

  7. Environmental and biotic controls on the evolutionary history of insect body size.

    PubMed

    Clapham, Matthew E; Karr, Jered A

    2012-07-01

    Giant insects, with wingspans as large as 70 cm, ruled the Carboniferous and Permian skies. Gigantism has been linked to hyperoxic conditions because oxygen concentration is a key physiological control on body size, particularly in groups like flying insects that have high metabolic oxygen demands. Here we show, using a dataset of more than 10,500 fossil insect wing lengths, that size tracked atmospheric oxygen concentrations only for the first 150 Myr of insect evolution. The data are best explained by a model relating maximum size to atmospheric environmental oxygen concentration (pO(2)) until the end of the Jurassic, and then at constant sizes, independent of oxygen fluctuations, during the Cretaceous and, at a smaller size, the Cenozoic. Maximum insect size decreased even as atmospheric pO(2) rose in the Early Cretaceous following the evolution and radiation of early birds, particularly as birds acquired adaptations that allowed more agile flight. A further decrease in maximum size during the Cenozoic may relate to the evolution of bats, the Cretaceous mass extinction, or further specialization of flying birds. The decoupling of insect size and atmospheric pO(2) coincident with the radiation of birds suggests that biotic interactions, such as predation and competition, superseded oxygen as the most important constraint on maximum body size of the largest insects. PMID:22665762

  8. What big eyes you have: the ecological role of giant pterygotid eurypterids.

    PubMed

    Anderson, Ross P; McCoy, Victoria E; McNamara, Maria E; Briggs, Derek E G

    2014-07-01

    Eurypterids are a group of extinct chelicerates that ranged for over 200 Myr from the Ordovician to the Permian. Gigantism is common in the group; about 50% of families include taxa over 0.8 m in length. Among these were the pterygotids (Pterygotidae), which reached lengths of over 2 m and were the largest arthropods that ever lived. They have been interpreted as highly mobile visual predators on the basis of their large size, enlarged, robust chelicerae and forward-facing compound eyes. Here, we test this interpretation by reconstructing the visual capability of Acutiramus cummingsi (Pterygotidae) and comparing it with that of the smaller Eurypterus sp. (Eurypteridae), which lacked enlarged chelicerae, and other arthropods of similar geologic age. In A. cummingsi, there is no area of lenses differentiated to provide increased visual acuity, and the interommatidial angles (IOA) do not fall within the range of high-level modern arthropod predators. Our results show that the visual acuity of A. cummingsi is poor compared with that of co-occurring Eurypterus sp. The ecological role of pterygotids may have been as predators on thin-shelled and soft-bodied prey, perhaps in low-light conditions or at night. PMID:25009243

  9. Superbubbles, Galactic Dynamos and the Spike Instability

    E-print Network

    Kulsrud, Russell M

    2015-01-01

    We draw attention to a problem with the alpha-Omega dynamo when it is applied to the origin of the galactic magnetic field under the assumption of perfect flux freezing. The standard theory involves the expulsion of undesirable flux and, because of flux freezing, the mass anchored on this flux also must be expelled. The strong galactic gravitational field makes this impossible on energetic grounds. It is shown that if only short pieces of the undesirable field lines are expelled, then mass can flow down along these field lines without requiring much energy. This expulsion of only short lines of force can be accomplished by a spike instability associated with gigantic astrophysical superbubbles. The physics of this instability is discussed and the results enable an estimate to be made of the number of spikes in the galaxy. It appears that there are probably enough spikes to cut all the undesirable lines into pieces as short as a couple of kiloparsecs during a dynamo time of a billion years. These cut pieces th...

  10. Geology and geochemistry of giant quartz veins from the Bundelkhand Craton, central India and their implications

    NASA Astrophysics Data System (ADS)

    Pati, J. K.; Patel, S. C.; Pruseth, K. L.; Malviya, V. P.; Arima, M.; Raju, S.; Pati, P.; Prakash, K.

    2007-12-01

    Giant quartz veins (GQVs; earlier referred to as ‘quartz reefs’) occurring in the Archean Bundelkhand Craton (29,000 km2) represent a gigantic Precambrian (˜2.15 Ga) silica-rich fluid activity in the central Indian shield. These veins form a striking curvilinear feature with positive relief having a preferred orientation NE-SW to NNE-SSW in the Bundelkhand Craton. Their outcrop widths vary from ?1 to 70m and pervasively extend over tens of kilometers along the strike over the entire craton. Numerous younger thin quartz veins with somewhat similar orientation cut across the giant quartz veins. They show imprints of strong brittle to ductile-brittle deformation, and in places are associated with base metal and gold incidences, and pyrophyllite-diaspore mineralization. The geochemistry of giant quartz veins were studied. Apart from presenting new data on the geology and geochemistry of these veins, an attempt has been made to resolve the long standing debate on their origin, in favour of an emplacement due to tectonically controlled polyphase hydrothermal fluid activity.

  11. When Did Carcharocles megalodon Become Extinct? A New Analysis of the Fossil Record

    PubMed Central

    Pimiento, Catalina; Clements, Christopher F.

    2014-01-01

    Carcharocles megalodon (“Megalodon”) is the largest shark that ever lived. Based on its distribution, dental morphology, and associated fauna, it has been suggested that this species was a cosmopolitan apex predator that fed on marine mammals from the middle Miocene to the Pliocene (15.9–2.6 Ma). Prevailing theory suggests that the extinction of apex predators affects ecosystem dynamics. Accordingly, knowing the time of extinction of C. megalodon is a fundamental step towards understanding the effects of such an event in ancient communities. However, the time of extinction of this important species has never been quantitatively assessed. Here, we synthesize the most recent records of C. megalodon from the literature and scientific collections and infer the date of its extinction by making a novel use of the Optimal Linear Estimation (OLE) model. Our results suggest that C. megalodon went extinct around 2.6 Ma. Furthermore, when contrasting our results with known ecological and macroevolutionary trends in marine mammals, it became evident that the modern composition and function of modern gigantic filter-feeding whales was established after the extinction of C. megalodon. Consequently, the study of the time of extinction of C. megalodon provides the basis to improve our understanding of the responses of marine species to the removal of apex predators, presenting a deep-time perspective for the conservation of modern ecosystems.

  12. The giant of Oxytricha bifaria: A peculiar cell differentiation triggered and controlled by cell to cell contacts.

    PubMed

    Ricci, N; Grandini, G; Bravi, A; Banchetti, R

    1991-06-21

    The heteromorphic life cycle of the freshwater hypotrich Oxytricha bifaria comprehends at least 3 phases: conjugating pairs, resting cysts and carnivorous giants. The gigantic forms represent unique adaptive devices which enable the species to survive in a certain environment when the normal bacterial food is exhausted. In this report several results are described which deal with the nature of the mechanisms underlying giant formation: (a) only cell to cell contacts (not species-specific) occurring among living specimens trigger this differentiation; (b) the higher the number of cells per ml, the shorter the "induction period", namely the time lag between the onset of the inducing conditions and the formation of the first giant; (c) it is now possible to separate and to distinguish experimentally, within the "induction period", two successive steps, namely "activation" and "predation"; (d) also the already-differentiated-giants (the so-called steadystate-giants) need cell to cell contacts to maintain their cell differentiation. The "Labile Memory Counter" hypothesis is proposed and discussed. PMID:23194704

  13. The changing pace of insular life: 5000 years of microevolution in the Orkney vole (Microtus arvalis orcadensis).

    PubMed

    Cucchi, Thomas; Barnett, Ross; Martínková, Natália; Renaud, Sabrina; Renvoisé, Elodie; Evin, Allowen; Sheridan, Alison; Mainland, Ingrid; Wickham-Jones, Caroline; Tougard, Christelle; Quéré, Jean Pierre; Pascal, Michel; Pascal, Marine; Heckel, Gerald; O'Higgins, Paul; Searle, Jeremy B; Dobney, Keith M

    2014-10-01

    Island evolution may be expected to involve fast initial morphological divergence followed by stasis. We tested this model using the dental phenotype of modern and ancient common voles (Microtus arvalis), introduced onto the Orkney archipelago (Scotland) from continental Europe some 5000 years ago. First, we investigated phenotypic divergence of Orkney and continental European populations and assessed climatic influences. Second, phenotypic differentiation among Orkney populations was tested against geography, time, and neutral genetic patterns. Finally, we examined evolutionary change along a time series for the Orkney Mainland. Molar gigantism and anterior-lobe hypertrophy evolved rapidly in Orkney voles following introduction, without any transitional forms detected. Founder events and adaptation appear to explain this initial rapid evolution. Idiosyncrasy in dental features among different island populations of Orkney voles is also likely the result of local founder events following Neolithic translocation around the archipelago. However, against our initial expectations, a second marked phenotypic shift occurred between the 4th and 12th centuries AD, associated with increased pastoral farming and introduction of competitors (mice and rats) and terrestrial predators (foxes and cats). These results indicate that human agency can generate a more complex pattern of morphological evolution than might be expected in island rodents. PMID:24957579

  14. Martian outflow channels: How did their source aquifers form, and why did they drain so rapidly?

    PubMed Central

    Rodriguez, J. Alexis P.; Kargel, Jeffrey S.; Baker, Victor R.; Gulick, Virginia C.; Berman, Daniel C.; Fairén, Alberto G.; Linares, Rogelio; Zarroca, Mario; Yan, Jianguo; Miyamoto, Hideaki; Glines, Natalie

    2015-01-01

    Catastrophic floods generated ~3.2 Ga by rapid groundwater evacuation scoured the Solar System’s most voluminous channels, the southern circum-Chryse outflow channels. Based on Viking Orbiter data analysis, it was hypothesized that these outflows emanated from a global Hesperian cryosphere-confined aquifer that was infused by south polar meltwater infiltration into the planet’s upper crust. In this model, the outflow channels formed along zones of superlithostatic pressure generated by pronounced elevation differences around the Highland-Lowland Dichotomy Boundary. However, the restricted geographic location of the channels indicates that these conditions were not uniform Boundary. Furthermore, some outflow channel sources are too high to have been fed by south polar basal melting. Using more recent mission data, we argue that during the Late Noachian fluvial and glacial sediments were deposited into a clastic wedge within a paleo-basin located in the southern circum-Chryse region, which was then completely submerged under a primordial northern plains ocean. Subsequent Late Hesperian outflow channels were sourced from within these geologic materials and formed by gigantic groundwater outbursts driven by an elevated hydraulic head from the Valles Marineris region. Thus, our findings link the formation of the southern circum-Chryse outflow channels to ancient marine, glacial, and fluvial erosion and sedimentation. PMID:26346067

  15. AB Blanket for Cities (for continual pleasant weather and protection from chemical, biological and radioactive weapons)

    E-print Network

    Alexander Bolonkin

    2009-02-04

    In a series of previous articles (see references) the author offered to cover a city or other important large installations or subregions by a transparent thin film supported by a small additional air overpressure under the form of an AB Dome. The building of a gigantic inflatable AB Dome over an empty flat surface is not difficult. However, if we want to cover a city, garden, forest or other obstacle course we cannot easily deploy the thin film over building or trees. In this article is suggested a new method which solves this problem. The idea is to design a double film blanket filled by light gas (for example, methane, hydrogen, or helium). Sections of this AB Blanket are lighter then air and fly in atmosphere. They can be made on a flat area (serving as an assembly area) and delivered by dirigible or helicopter to station at altitude over the city. Here they connect to the already assembled AB Blanket subassemblies, cover the city in an AB Dome and protect it from bad weather, chemical, biological and radioactive fallout or particulates. After finish of dome building the light gas can be changed by air. Two projects for Manhattan (NY, USA) and Moscow (Russia) are targets for a sample computation.

  16. AB Blanket for Cities (for continual pleasant weather and protection from chemical, biological and radioactive weapons)

    E-print Network

    Bolonkin, Alexander

    2009-01-01

    In a series of previous articles (see references) the author offered to cover a city or other important large installations or subregions by a transparent thin film supported by a small additional air overpressure under the form of an AB Dome. The building of a gigantic inflatable AB Dome over an empty flat surface is not difficult. However, if we want to cover a city, garden, forest or other obstacle course we cannot easily deploy the thin film over building or trees. In this article is suggested a new method which solves this problem. The idea is to design a double film blanket filled by light gas (for example, methane, hydrogen, or helium). Sections of this AB Blanket are lighter then air and fly in atmosphere. They can be made on a flat area (serving as an assembly area) and delivered by dirigible or helicopter to station at altitude over the city. Here they connect to the already assembled AB Blanket subassemblies, cover the city in an AB Dome and protect it from bad weather, chemical, biological and rad...

  17. Baleen boom and bust: a synthesis of mysticete phylogeny, diversity and disparity

    PubMed Central

    Marx, Felix G.; Fordyce, R. Ewan

    2015-01-01

    A new, fully dated total-evidence phylogeny of baleen whales (Mysticeti) shows that evolutionary phases correlate strongly with Caenozoic modernization of the oceans and climates, implying a major role for bottom-up physical drivers. The phylogeny of 90 modern and dated fossil species suggests three major phases in baleen whale history: an early adaptive radiation (36–30?Ma), a shift towards bulk filter-feeding (30–23?Ma) and a climate-driven diversity loss around 3?Ma. Evolutionary rates and disparity were high following the origin of mysticetes around 38?Ma, coincident with global cooling, abrupt Southern Ocean eutrophication and the development of the Antarctic Circumpolar Current (ACC). Subsequently, evolutionary rates and disparity fell, becoming nearly constant after approximately 23?Ma as the ACC reached its full strength. By contrast, species diversity rose until 15?Ma and then remained stable, before dropping sharply with the onset of Northern Hemisphere glaciation. This decline coincided with the final establishment of modern mysticete gigantism and may be linked to glacially driven variability in the distribution of shallow habitats or an increased need for long-distance migration related to iron-mediated changes in glacial marine productivity. PMID:26064636

  18. No evidence for directional evolution of body mass in herbivorous theropod dinosaurs

    PubMed Central

    Zanno, Lindsay E.; Makovicky, Peter J.

    2013-01-01

    The correlation between large body size and digestive efficiency has been hypothesized to have driven trends of increasing mass in herbivorous clades by means of directional selection. Yet, to date, few studies have investigated this relationship from a phylogenetic perspective, and none, to our knowledge, with regard to trophic shifts. Here, we reconstruct body mass in the three major subclades of non-avian theropod dinosaurs whose ecomorphology is correlated with extrinsic evidence of at least facultative herbivory in the fossil record—all of which also achieve relative gigantism (more than 3000 kg). Ordinary least-squares regressions on natural log-transformed mean mass recover significant correlations between increasing mass and geological time. However, tests for directional evolution in body mass find no support for a phylogenetic trend, instead favouring passive models of trait evolution. Cross-correlation of sympatric taxa from five localities in Asia reveals that environmental influences such as differential habitat sampling and/or taphonomic filtering affect the preserved record of dinosaurian body mass in the Cretaceous. Our results are congruent with studies documenting that behavioural and/or ecological factors may mitigate the benefit of increasing mass in extant taxa, and suggest that the hypothesis can be extrapolated to herbivorous lineages across geological time scales. PMID:23193135

  19. Overview of laser-driven generation of electron-positron beams

    NASA Astrophysics Data System (ADS)

    Sarri, G.; Dieckmann, M. E.; Kourakis, I.; di Piazza, A.; Reville, B.; Keitel, C. H.; Zepf, M.

    2015-08-01

    Electron-positron (e-p) plasmas are widely thought to be emitted, in the form of ultra-relativistic winds or collimated jets, by some of the most energetic or powerful objects in the Universe, such as black-holes, pulsars, and quasars. These phenomena represent an unmatched astrophysical laboratory to test physics at its limit and, given their immense distance from Earth (some even farther than several billion light years), they also provide a unique window on the very early stages of our Universe. However, due to such gigantic distances, their properties are only inferred from the indirect interpretation of their radiative signatures and from matching numerical models: their generation mechanism and dynamics still pose complicated enigmas to the scientific community. Small-scale reproductions in the laboratory would represent a fundamental step towards a deeper understanding of this exotic state of matter. Here we present recent experimental results concerning the laser-driven production of ultra-relativistic e-p beams. In particular, we focus on the possibility of generating beams that present charge neutrality and that allow for collective effects in their dynamics, necessary ingredients for the testing pair-plasma physics in the laboratory. A brief discussion of the analytical and numerical modelling of the dynamics of these plasmas is also presented in order to provide a summary of the novel plasma physics that can be accessed with these objects. Finally, general considerations on the scalability of laboratory plasmas up to astrophysical scenarios are given.

  20. Study of Historical 4B/X17 Mega Flare on 28 October 2003 (P58)

    NASA Astrophysics Data System (ADS)

    Uddin, W.; Chandra, R.; Ali, S. S.

    2006-11-01

    wuddin_99@yahoo.com We analysed multi-wavelength data of 28 October 2003 4B/X17.2 class extremely energetic parallel ribbon solar flare, which occurred in NOAA 10486. The flare was well observed in H-alpha at ARIES, Nainital and various space (SOHO, TRACE, RHESSI, WIND etc.) and ground based Observatories. The H-alpha observations show the stretching/detwisting and eruption of helically twisted S shaped (sigmoid) filament in the South-West direction of the active region with bright shock front followed by rapid increase in intensity and area of the gigantic flare. The flare is associated with a bright/fast full halo earth directed CME, strong type II, III and IV radio bursts, an intense proton event and GLE. It seems that the filament eruption triggered the halo CME because the helical structure is clearly visible in the SOHO/LASCO C2, C3 images. This indicates helicity transfer from chromosphere to corona and interplanetary medium. The magnetic field of the flaring region was most complex with high magnetic shear. From the above analysis we feel that the energy buildup/release process of this unique flare support helically twisted magnetic flux rope model.

  1. Advanced Materials for Sustainable, Clean Energy Future

    SciTech Connect

    Yang, Zhenguo

    2009-04-01

    The current annual worldwide energy consumption stands at about 15 terawatts (TW, x1012 watts). Approximately 80% of it is supplied from fossil fuels: oil (34 %), coal (25 %), and natural gas (21 %). Biomass makes up 8% of the energy supply, nuclear energy accounts for 6.5 %, hydropower has a 2% share and other technologies such as wind and solar make up the rest. Even with aggressive conservation and new higher efficiency technology development, worldwide energy demand is predicted to double to 30 TW by 2050 and triple to 46 TW by the end of the century. Meanwhile oil and natural gas production is predicted to peak over the next few decades. Abundant coal reserves may maintain the current consumption level for longer period of time than the oil and gas. However, burning the fossil fuels leads to a serious environmental consequence by emitting gigantic amount of green house gases, particularly CO2 emissions which are widely considered as the primary contributor to global warming. Because of the concerns over the greenhouse gas emission, many countries, and even some states and cities in the US, have adopted regulations for limiting CO2 emissions. Along with increased CO2 regulations, is an emerging trend toward carbon “trading,” giving benefits to low “carbon footprint” industries, while making higher emitting industries purchase carbon “allowances”. There have been an increasing number of countries and states adopting the trade and cap systems.

  2. Control of Regional and Global Weather

    E-print Network

    Alexander Bolonkin

    2007-01-09

    Author suggests and researches a new revolutionary idea for regional and global weather control. He offers to cover cities, bad regions of country, full country or a continent by a thin closed film with control clarity located at a top limit of the Earth troposphere (4 - 6 km). The film is supported at altitude by small additional atmospheric pressure and connected to ground by thin cables. It is known, the troposphere defines the Earth weather. Authors show this closed dome allows to do a full control of the weather in a given region (the day is always fine, the rain is only in night, no strong wind). The average Earth (white cloudy) reflectance equal 0.3 - 0.5. That means the Earth losses about 0.3 - 0.5 of a solar energy. The dome controls the clarity of film and converts the cold regions to subtropics and creates the hot deserts, desolate wildernesses to the prosperous regions with temperate climate. That is a realistic and the cheapest method of the weather control in the Earth at the current time. Key words: Global weather control, gigantic film dome, converting a cold region to subtropics, converting desolate wilderness to a prosperous region.

  3. A soft magnetic material for power supply systems of high energy physics experiments

    NASA Astrophysics Data System (ADS)

    Baccaro, S.; Cova, P.; Delmonte, N.; Ghisolfi, E.; Lanza, A.

    2013-01-01

    Most of the high energy physics experiments require their detectors to be embedded in a high intensity magnetic field. In particular the biggest of them, ATLAS, running in the CERN Large Hadron Collider (LHC) particle accelerator, generates a field of 2 T by means of a gigantic toroidal magnet working in open air. Its future phase 2 upgrade plans to move the DC/DC power supplies from the present positions on the external balconies directly on the detectors, where the field is of the order of 1 T. This presentation describes the development of samples made of special magnetic material for inductor cores suitable to work in such an environment. Starting from iron-silicon powders, at FN plant a plastic forming process, based on powder extrusion, injection moulding and sintering, was developed. To get the best compromise between the forming process requirements (good coupling among the metallic powder and the organic components to assure the right mouldability) and the debinding and sintering conditions, several mixtures (with different percentages and kind of organic additives) were experimented. A proper mould was designed and realized to get torous-shaped prototypes. The preliminary results of the physical-microstructural characterization performed on the first prototypes made will be shown.

  4. A rapid hydrolysis method and DABS-Cl derivatization for complete amino acid analysis of octreotide acetate by reversed phase HPLC.

    PubMed

    Akhlaghi, Yousef; Ghaffari, Solmaz; Attar, Hossein; Alamir Hoor, Amir

    2015-11-01

    Octreotide as a synthetic cyclic octapeptide is a somatostatin analog with longer half-life and more selectivity for inhibition of the growth hormone. The acetate salt of octreotide is currently used for medical treatment of somatostatin-related disorders such as endocrine and carcinoid tumors, acromegaly, and gigantism. Octreotide contains both cysteine and tryptophan residues which make the hydrolysis part of its amino acid analysis procedure very challenging. The current paper introduces a fast and additive-free method which preserves tryptophan and cysteine residues during the hydrolysis. Using only 6 M HCl, this hydrolysis process is completed in 30 min at 150 °C. This fast hydrolysis method followed by pre-column derivatization of the released amino acids with 4-N,N-dimethylaminoazobenzene-4'-sulfonyl chloride (DABS-Cl) which takes only 20 min, makes it possible to do the complete amino acid analysis of an octreotide sample in a few hours. The highly stable-colored DABS-Cl derivatives can be detected in 436 nm in a reversed phase chromatographic system, which eliminates spectral interferences to a great extent. The amino acid analysis of octreotide acetate including hydrolysis, derivatization, and reversed phase HPLC determination was validated according to International Conference of Harmonization (ICH) guidelines. PMID:26002809

  5. Interaction of the Ultra Relativistic Pulsar Plasma with the Upper Atmosphere of the Star-Companion

    SciTech Connect

    Ulyanov, Oleg M.

    2010-08-12

    The basic types of losses of the ultra relativistic electron-positron pulsar plasma in the upper atmosphere of a star-companion are considered. These types include: ionization losses of the medium atoms, their excitation losses, the losses connected with the energies transferred to the particles of plasma, the formation losses of the recoil {delta} electrons and Cherenkov radiation losses of moving particles, bremsstrahlung losses, the synchrotron radiation losses and the losses, connected with the inverse Compton emission. It is shown that the most rapid component of pulsar plasma can reach the top of convective zone. The range of kinetic energies of the plasma particles that reach the upper boundary of the convection zone will correspond to the range of the gigantic dipole resonance (GDR). The result of interaction of the pulsar plasma and of the upper atmosphere of examined star-companion will be the non-homogeneous heating of the local zones of photosphere and boundary between the photosphere and zone of convection on the different depths.

  6. Building logical qubits in a superconducting quantum computing system

    E-print Network

    Jay M. Gambetta; Jerry M. Chow; Matthias Steffen

    2015-10-15

    The technological world is in the midst of a quantum computing and quantum information revolution. Since Richard Feynman's famous "plenty of room at the bottom" lecture, hinting at the notion of novel devices employing quantum mechanics, the quantum information community has taken gigantic strides in understanding the potential applications of a quantum computer and laid the foundational requirements for building one. We believe that the next significant step will be to demonstrate a quantum memory, in which a system of interacting qubits stores an encoded logical qubit state longer than the incorporated parts. Here, we describe the important route towards a logical memory with superconducting qubits, employing a rotated version of the surface code. The current status of technology with regards to interconnected superconducting-qubit networks will be described and near-term areas of focus to improve devices will be identified. Overall, the progress in this exciting field has been astounding, but we are at an important turning point where it will be critical to incorporate engineering solutions with quantum architectural considerations, laying the foundation towards scalable fault-tolerant quantum computers in the near future.

  7. Energy expenditure in Crocidurinae shrews (Insectivora): is metabolism a key component of the insular syndrome?

    PubMed

    Magnanou, Elodie; Fons, Roger; Blondel, Jacques; Morand, Serge

    2005-11-01

    A cascade of morphological, ecological, demographical and behavioural changes operates within island communities compared to mainland. We tested whether metabolic rates change on islands. Using a closed circuit respirometer, we investigated resting metabolic rate (RMR) of three species of Crocidurinae shrews: Suncus etruscus, Crocidura russula, and C. suaveolens. For the latter, we compared energy expenditure of mainland and island populations. Our measurements agree with those previously reported for others Crocidurinae: the interspecific comparison (ANCOVA) demonstrated an allometric relation between energy requirements and body mass. Energy expenditure also scaled with temperature. Island populations (Corsica and Porquerolles) of C. suaveolens differed in size from mainland (gigantism). A GLM showed a significant relationship between energy expenditure, temperature, body mass and locality. Mass specific RMR allometrically scales body mass, but total RMR does not significantly differ between mainland and island, although island shrews are giant. Our results are consistent with other studies: that demonstrated that the evolution of mammalian metabolism on islands is partially independent of body mass. In relation to the insular syndrome, we discuss how island selective forces (changes in resource availability, decrease in competition and predation pressures) can operate in size and physiological adjustments. PMID:16154371

  8. Thermal Expansion Anomaly Regulated by Entropy

    PubMed Central

    Liu, Zi-Kui; Wang, Yi; Shang, ShunLi

    2014-01-01

    Thermal expansion, defined as the temperature dependence of volume under constant pressure, is a common phenomenon in nature and originates from anharmonic lattice dynamics. However, it has been poorly understood how thermal expansion can show anomalies such as colossal positive, zero, or negative thermal expansion (CPTE, ZTE, or NTE), especially in quantitative terms. Here we show that changes in configurational entropy due to metastable micro(scopic)states can lead to quantitative prediction of these anomalies. We integrate the Maxwell relation, statistic mechanics, and first-principles calculations to demonstrate that when the entropy is increased by pressure, NTE occurs such as in Invar alloy (Fe3Pt, for example), silicon, ice, and water, and when the entropy is decreased dramatically by pressure, CPTE is expected such as in anti-Invar cerium, ice and water. Our findings provide a theoretic framework to understand and predict a broad range of anomalies in nature in addition to thermal expansion, which may include gigantic electrocaloric and electromechanical responses, anomalously reduced thermal conductivity, and spin distributions. PMID:25391631

  9. Emissions of VOCs at urban petrol retail distribution centres in India (Delhi and Mumbai).

    PubMed

    Srivastava, Anjali; Joseph, A E; More, Ajit; Patil, Sunil

    2005-10-01

    Air pollution has assumed gigantic proportion killing almost half a million Asians every year. Urban pollution mainly comprises of emissions from buses, trucks, motorcycle other forms of motorized transport and its supporting activities. As Asia's cities continue to expand the number of vehicles have risen resulting in greater pollution. Fugitive emissions from retail distribution center in urban area constitute a major source. Petrol vapours escape during refueling adding pollutants like benzene, toluene, ethylbenzene and xylene to ambient air. This paper discusses a study on fugitive emissions of Volatile Organic Compounds (VOC) at some refueling station in two metropolitan cities of India, i.e., Mumbai and Delhi. Concentration of VOCs in ambient air at petrol retail distribution center is estimated by using TO-17 method. Concentration of benzene in ambient air in Delhi clearly shows the effect of intervention in use of petroleum and diesel fuel and shift to CNG. Chemical Mass Balance (CMB) model is used to estimate source contributions. At Delhi besides diesel combustion engines, refueling emissions are also major sources. At Mumbai evaporative emissions are found to contribute maximum to Total VOC (TVOC) concentration in ambient air. PMID:16240200

  10. Cell size versus body size in geophilomorph centipedes

    NASA Astrophysics Data System (ADS)

    Moretto, Marco; Minelli, Alessandro; Fusco, Giuseppe

    2015-04-01

    Variation in animal body size is the result of a complex interplay between variation in cell number and cell size, but the latter has seldom been considered in wide-ranging comparative studies, although distinct patterns of variation have been described in the evolution of different lineages. We investigated the correlation between epidermal cell size and body size in a sample of 29 geophilomorph centipede species, representative of a wide range of body sizes, from 6 mm dwarf species to gigantic species more than 200 mm long, exploiting the marks of epidermal cells on the overlying cuticle in the form of micro-sculptures called scutes. We found conspicuous and significant variation in average scute area, both between suprageneric taxa and between genera, while the within-species range of variation is comparatively small. This supports the view that the average epidermal cell size is to some extent taxon specific. However, regression analyses show that neither body size nor the number of leg-bearing segments explain this variation, which suggests that cell size is not an usual target of change for body size evolution in this group of arthropods, although there is evidence of its correlation with other morphological variables, like cuticle thickness. Scute sizes of miniaturized geophilomorph species are well within the range of the lineage to which the species belong, suggesting recent evolutionary transitions to smaller body size.

  11. The Kunlun Fault

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The Kunlun fault is one of the gigantic strike-slip faults that bound the north side of Tibet. Left-lateral motion along the 1,500-kilometer (932-mile) length of the Kunlun has occurred uniformly for the last 40,000 years at a rate of 1.1 centimeter per year, creating a cumulative offset of more than 400 meters. In this image, two splays of the fault are clearly seen crossing from east to west. The northern fault juxtaposes sedimentary rocks of the mountains against alluvial fans. Its trace is also marked by lines of vegetation, which appear red in the image. The southern, younger fault cuts through the alluvium. A dark linear area in the center of the image is wet ground where groundwater has ponded against the fault. Measurements from the image of displacements of young streams that cross the fault show 15 to 75 meters (16 to 82 yards) of left-lateral offset. The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) acquired the visible light and near infrared scene on July 20, 2000. Image courtesy NASA/GSFC/MITI/ERSDAC/JAROS, and the U.S./Japan ASTER Science Team

  12. Protection of Cities from Small Rockets, Missiles, Projectiles and Mortar Shells

    E-print Network

    Bolonkin, Alexander

    2008-01-01

    The authors suggest a low cost closed AB-Dome, which may protect small cities such as Sederot from rockets, mortar shells, chemical and biological weapons. The offered AB-Dome is also very useful in peacetime because it protects the city from outside weather (violent storms, hail) and creates a fine climate within the Dome. The roughly hemispherical AB-Dome is a gigantic inflated thin transparent film, located at altitude up to 1 - 5 kilometers, which converts the city into a closed-loop air system. The film may be armored with a basalt or steel grille or cloth pocket-retained stones that destroy (by collision or detonation) incoming rockets, shells and other projectiles. Such an AB-Dome would even protect the city in case of a third-party nuclear war involving temporary poisoning of the Earth atmosphere by radioactive dust. The building of the offered dome is easy; the film spreads on the ground, the fan engines turn on and the cover rises to the needed altitude and is supported there by a small internal ove...

  13. Resonances and Tides in Natural Satellites Systems. (Breton Title: Ressonâncias e Marés em Sistemas de Satélites Naturais.) Resonancias y Mareas en Sistemas de Satélites Naturales

    NASA Astrophysics Data System (ADS)

    Callegari, Nelson, Jr.

    2006-12-01

    In this work we describe some aspects of the dynamics of the mean-motion resonances. Emphasis to the case of resonances between regular satellites of the giant planets will be given, even so some aspects of the physics of the resonances in extra-solar planetary systems are also briefly treated. The role of the resonances in satellites systems is discussed through examples, showing how certain resonances, and its relations with the tidal dissipation effects, can be the key of the explanation of some phenomena still not explained in the Solar System. Amongst some examples we highlight the problem of the resurfacing of Enceladus, the existence of active volcanoes in Io, and the possible existence of the subsurface ocean in Europe. This work has as objective the divulgation of some topics in Celestial Mechanics and Planetary Sciences for an undergraduate public in exact sciences, as Astronomy and Physics, and not their detailed description. Neste trabalho descrevemos alguns aspectos da dinâmica de ressonâncias de movimentos médios. Será dada ênfase maior ao caso de ressonâncias entre satélites regulares dos planetas gigantes, embora alguns aspectos da física das ressonâncias em sistemas planetários extra-solares também sejam discutidos brevemente. A importância do estudo de ressonâncias em sistemas de satélites é discutida mais detalhadamente através de exemplos, mostrando como certas ressonâncias e suas relações com efeitos de dissipação de maré podem ser a chave de parte da explicação de alguns fenômenos ainda não explicados no Sistema Solar. Dentre vários exemplos destacamos o problema da remodelagem da superfície do satélite Enceladus, a existência de vulcões ativos em Io, e a possível existência do oceano subterrâneo em Europa. Este trabalho tem como objetivo a divulgação de alguns tópicos de Mecânica Celeste e Planetologia para um público de nível de graduação em disciplinas na área de exatas, em especial Astronomia e Física, e não a descrição detalhada dos conceitos aqui discutidos. Describimos en este trabajo algunos aspectos de la dinámica de resonancias de movimientos promedio. Será dado un énfasis mayor al caso de las resonancias entre satélites regulares de los planetas gigantes, aunque también son discutidos brevemente algunos aspectos de la física de resonancias en sistemas panetarios extrasolares. La importancia del estudio de las resonancias en sistemas de satélites es discutida más detalladamente através de ejemplos, mostrando cómo ciertas resonancias y los efectos de disipación por mareas pueden ser la clave de parte de la explicación de algunos fenómenos aún no comprendidos en el Sistema Solar. Entre varios ejemplos se destacan el problema de la superficie remodelada del satélite Enceladus, la existencia de volcanes activos en Io y la posible existencia de un océano subterráneo en Europa. Este trabajo tiene como objetivo la divulgación de algunos tópicos en Mecánica Celeste y Planetología para un público universitario de ciencias exactas, en particular Astronomía y Física, y no la descripción detallada de los conceptos aquí discutidos.

  14. Rare normal faulting earthquake induced by subduction megaquake: example from 2011 Tohoku-oki earthquake

    NASA Astrophysics Data System (ADS)

    Ishiyama, T.; Sugito, N.; Echigo, T.; Sato, H.; Suzuki, T.

    2012-04-01

    A month after March 11 gigantic M9.0 Tohoku-oki earthquake, M7.0 intraplate earthquake occurred at a depth of 5 km on April 11 beneath coastal area of near Iwaki city, Fukushima prefecture. Focal mechanism of the mainshock indicates that this earthquake is a normal faulting event. Based on field reconnaissance and LIDAR mapping by Geospatial Information Authority of Japan, we recognized coseismic surface ruptures, presumably associated with the main shock. Coseismic surface ruptures extend NNW for about 11 km in a right-stepping en echelon manner. Geomorphic expressions of these ruptures commonly include WWS-facing normal fault scarps and/or drape fold scarp with open cracks on their crests, on the hanging wall sides of steeply west-dipping normal fault planes subparallel to Cretaceous metamorphic rocks. Highest topographic scarp height is about 2.3 m. In this study we introduce preliminary results of a trenching survey across the coseismic surface ruptures at Shionohira site, to resolve timing of paleoseismic events along the Shionohira fault. Trench excavations were carried out at two sites (Ichinokura and Shionohira sites) in Iwaki, Fukushima. At Shionohira site a 2-m-deep trench was excavated across the coseismic fault scarp emerged on the alluvial plain on the eastern flank of the Abukuma Mountains. On the trench walls we observed pairs of steeply dipping normal faults that deform Neogene to Paleogene conglomerates and unconformably overlying, late Quaternary to Holocene fluvial units. Sense of fault slip observed on the trench walls (large dip-slip with small sinistral component) is consistent with that estimated from coseismic surface ruptures. Fault throw estimated from separation of piercing points on lower Unit I and vertical structural relief on folded upper Unit I is consistent with topographic height of the coseismic fault scarp at the trench site. In contrast, vertical separation of Unit II, unconformably overlain by Unit I, is measured as about 1.5 m, twice as large as coseismic vertical component of slip, indicative of penultimate seismic event prior to the 2011 earthquake. Abrupt thickening of overlying Unit I may also suggest preexisting topographic relief prior to its deposition. Radiocarbon dating of charred materials included in event horizons and tephrostratigraphy at two sites indicate that penultimate event prior to the 2011 event might occurred at about 40 ka. This normal fault earthquake is in contrast to compressional or neutral stress regimes in Tohoku region before the 2011 megaquake and rarity of the normal faulting earthquake inferred from these paleoseismic studies may reflect its mechanical relation to the gigantic megathrust earthquakes, such as unusual, enhanced extensional stress on the hangingwall block induced by mainshock and/or postseismic creep after the M~9 earthquake.

  15. HUBBLE VIEWS A STARRY RING WORLD BORN IN A HEAD-ON COLLISION

    NASA Technical Reports Server (NTRS)

    2002-01-01

    [Right] - A rare and spectacular head-on collision between two galaxies appears in this NASA Hubble Space Telescope true-color image of the Cartwheel Galaxy, located 500 million light-years away in the constellation Sculptor. The new details of star birth resolved by Hubble provide an opportunity to study how extremely massive stars are born in large fragmented gas clouds. The striking ring-like feature is a direct result of a smaller intruder galaxy -- possibly one of two objects to the right of the ring -- that careened through the core of the host galaxy. Like a rock tossed into a lake, the collision sent a ripple of energy into space, plowing gas and dust in front of it. Expanding at 200,000 miles per hour, this cosmic tsunami leaves in its wake a firestorm of new star creation. Hubble resolves bright blue knots that are gigantic clusters of newborn stars and immense loops and bubbles blown into space by exploding stars (supernovae) going off like a string of firecrackers. The Cartwheel Galaxy presumably was a normal spiral galaxy like our Milky Way before the collision. This spiral structure is beginning to re-emerge, as seen in the faint arms or spokes between the outer ring and bulls-eye shaped nucleus. The ring contains at least several billion new stars that would not normally have been created in such a short time span and is so large (150,000 light-years across) our entire Milky Way Galaxy would fit inside. Hubble's new view does not solve the mystery as to which of the two small galaxies might have been the intruder. The blue galaxy is disrupted and has new star formation which strongly suggests it is the interloper. However, the smoother-looking companion has no gas, which is consistent with the idea that gas was stripped out of it during passage through the Cartwheel Galaxy. [Top Left] - Hubble's detailed view shows the knot-like structure of the ring, produced by large clusters of new star formation. Hubble also resolves the effects of thousands of supernovae on the ring structure. One flurry of explosions blew a hole in the ring and formed a giant bubble of hot gas. Secondary star formation on the edge of this bubble appears as an arc extending beyond the ring. [Bottom Left] - Hubble resolves remarkable new detail in the galaxy's core. The reddish color of this region indicates that it contains a tremendous amount of dust and embedded star formation. Bright pinpoints of light are gigantic young star clusters. The picture was taken with the Wide Field Planetary Camera-2 on October 16, 1994. It is a combination of two images, taken in blue and near-infrared light. Credit: Kirk Borne (ST ScI), and NASA

  16. Shedding Light on the Cosmic Skeleton

    NASA Astrophysics Data System (ADS)

    2009-11-01

    Astronomers have tracked down a gigantic, previously unknown assembly of galaxies located almost seven billion light-years away from us. The discovery, made possible by combining two of the most powerful ground-based telescopes in the world, is the first observation of such a prominent galaxy structure in the distant Universe, providing further insight into the cosmic web and how it formed. "Matter is not distributed uniformly in the Universe," says Masayuki Tanaka from ESO, who led the new study. "In our cosmic vicinity, stars form in galaxies and galaxies usually form groups and clusters of galaxies. The most widely accepted cosmological theories predict that matter also clumps on a larger scale in the so-called 'cosmic web', in which galaxies, embedded in filaments stretching between voids, create a gigantic wispy structure." These filaments are millions of light years long and constitute the skeleton of the Universe: galaxies gather around them, and immense galaxy clusters form at their intersections, lurking like giant spiders waiting for more matter to digest. Scientists are struggling to determine how they swirl into existence. Although massive filamentary structures have been often observed at relatively small distances from us, solid proof of their existence in the more distant Universe has been lacking until now. The team led by Tanaka discovered a large structure around a distant cluster of galaxies in images they obtained earlier. They have now used two major ground-based telescopes to study this structure in greater detail, measuring the distances from Earth of over 150 galaxies, and, hence, obtaining a three-dimensional view of the structure. The spectroscopic observations were performed using the VIMOS instrument on ESO's Very Large Telescope and FOCAS on the Subaru Telescope, operated by the National Astronomical Observatory of Japan. Thanks to these and other observations, the astronomers were able to make a real demographic study of this structure, and have identified several groups of galaxies surrounding the main galaxy cluster. They could distinguish tens of such clumps, each typically ten times as massive as our own Milky Way galaxy - and some as much as a thousand times more massive - while they estimate that the mass of the cluster amounts to at least ten thousand times the mass of the Milky Way. Some of the clumps are feeling the fatal gravitational pull of the cluster, and will eventually fall into it. "This is the first time that we have observed such a rich and prominent structure in the distant Universe," says Tanaka. "We can now move from demography to sociology and study how the properties of galaxies depend on their environment, at a time when the Universe was only two thirds of its present age." The filament is located about 6.7 billion light-years away from us and extends over at least 60 million light-years. The newly uncovered structure does probably extend further, beyond the field probed by the team, and hence future observations have already been planned to obtain a definite measure of its size. More information This research was presented in a paper published as a letter in the Astronomy & Astrophysics Journal: The spectroscopically confirmed huge cosmic structure at z = 0.55, by Tanaka et al. The team is composed of Masayuki Tanaka (ESO), Alexis Finoguenov (Max-Planck-Institute for Extraterrestrial Physics, Garching, Germany and University of Maryland, Baltimore, USA), Tadayuki Kodama (National Astronomical Observatory of Japan, Tokyo, Japan), Yusei Koyama (Department of Astronomy, University of Tokyo, Japan), Ben Maughan (H.H. Wills Physics Laboratory, University of Bristol, UK) and Fumiaki Nakata (Subaru Telescope, National Astronomical Observatory of Japan). ESO, the European Southern Observatory, is the foremost intergovernmental astronomy organisation in Europe and the world's most productive astronomical observatory. It is supported by 14 countries: Austria, Belgium, the Czech Republic, Denmark, France, Finland, Germany, Italy, the

  17. Transregional lineament of Central Asia, its magmatism, metallogeny and seismicity

    NASA Astrophysics Data System (ADS)

    Sidorova, I.

    2004-12-01

    The analysis of the place and role of such large fault as Central Kyzylkum, North Nurata and South Ferghana, Atbashin, which were regarded earlier as separate independent structures led us to the idea that they are parts of a single global structure. We suggest that it should be called "Transregional lineament of Central Asia". Transregional lineament of Central Asia is multisutured long-term, and in the nodal points of some parts it is complicated by deep fault zones of «Anti Tien-Shan» trend.There are large gold ore deposits (Muruntau, Kokpatas, Kumtor) in the intersection of some of these faults. Within the lineament there are 4 mafite - ultramafite associations of different age, that are presented as isolated or combined blocks, zones and regions. The most ancient is ophiolite one (I association). Best of all it is developed in Sultanuvais and Northern Tamdytau, Uzbekistan. The second, rift association of this belt is picrite-gabbro-diabase-alkali-olivine-basalt is widespread within the belt (northern Bukantau, northern Nuratau, northern slope of the Altay ridge).The third association is peridotite-gabbroic. It is represented by the Tebinbulak intrusive of Sultanuvais. Coverings, small stocks, dikes and explosion tubes formed by potassic mafite-ultramafites ore related to much later inter-plate (P-T) occurrences of mafite-ultramafite magmatism (IY association). On Kyrgyzstan's territory the studied lineament is observed as a system of regional deep faults -Atbashi-Inylchek and Southern Ferghana, with which the ophiolite ultramafite-mafite formation is associated. The rocks have the traces of tectonic movements, which can be the ground to regard them as protrusions. Tectonically, the vast territory of Mongolia is divided into two large blocks: northern and southern. This part of the lineament called Transmongolian. This part is week studied-a special investigation was only carried out in its western part - Bulgan fault. Thus, in the presence of linear-stretched sublatitudinal metallogenic belts within the area of the studied transregional lineament in the Central Asian region, the most prospective ore deposits'assemblages are located in the intersection of these belts as deep faults of meridional, north-eastern and north-western trend. The following deposits are situated in such intersection zones: the largest in Eurasia Muruntau gold deposit, a large deposit Kumtor, Kyrgyzstan; and the gigantic class deposit - Ashi in China.Anomalously increased heat flow density (HFD) values both Muruntau deposit (according to our data- up to 85 mW/m2), and for Kumtor deposit (according to E.A.Ljubimova data - up to 130 mW/m2 ) indicate the deep character of dislocations. Interpretation of seismic observations revealed a transregional zone with the width of up to 80 km in the upper part of Kyzylkums crust. The strip is located in the relief of Moho surface, and is discordant to the general trend of premesozoic structures. Abrupt variations of the Moho boundary with vertical movement of up to 10 km are observed in the eastern end of the Issyk-Kul valley and at the boundary of Northern and Middle Tien Shan, along the Nikolaev line. In conclusion we'd like to note that such structures are well-known in American, Australian and other continents.They are recognized as deep structures and served as channels for the heat energy, magmas and fluids to come out of the core and mantle of the Earth. In this connection, activity of these structures are accompanied by the presence of various magamatic, endogenous as well as gigantic ore deposits.

  18. Gigas Meets Ulysses

    NASA Technical Reports Server (NTRS)

    2003-01-01

    [figure removed for brevity, see original site]

    Released 9 July 2003

    Roughly halfway between the great volcanoes of Olympus Mons and Pavonis Mons, the graben (troughs) of Ulysses Fossae intersect with the furrows of Gigas (gigantic) Sulci. A clear time sequence is evident: first came the formation of the sulci terrain (to the left), which then was fractured by graben radial to Olympus Mons, followed by flooding of lava. All but the deepest graben are filled by lava in the topographic low between the two volcanic rises.

    Image information: VIS instrument. Latitude 11.8, Longitude 234.3 East (125.7 West). 19 meter/pixel resolution.

    Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.

    NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena.

  19. Combining ECS Exploration and Scientific Interest: The Case of the Demarara Plateau Offshore French Guiana (Invited)

    NASA Astrophysics Data System (ADS)

    Roest, W. R.; Loncke, L.; Loubrieu, B.

    2013-12-01

    The French national program for the extension of the continental shelf, EXTRAPLAC, started in 2002 with funding from the French Government. It is let by Ifremer, with as principle partners the SHOM (Hydrographic and Oceanographic Service of the Navy), IPEV (French Polar Institute) and IFP Energies Nouvelles. Its aim is to make submissions for extended continental shelf beyond 200 nm to the Commission on the Limits of the Continental Shelf under the UN Convention on the Law of the Sea. Nine submissions, of which 3 are joint with neighboring states, have been made thus far, concerning areas off metropolitan France and its overseas territories. In total, over 360 days of ship time was needed to explore these vast and dispersed areas, in the Atlantic, Pacific and Indian Oceans. The data collected include multibeam bathymetry, seismic reflection and some rock sampling. In this presentation we will describe how the EXTRAPLAC cruise offshore French Guiana (GUYAPLAC, R/V L'Atalante, 2003) let to new scientific results for this transform type margin, in particular in the area of the Demerara Plateau. These include the discovery of gigantic submarine land slides in the subsurface, and associated fluid escape features on the seafloor. A scientific collaboration between the EXTRAPLAC team and academia let to a follow-up cruise proposal to further explore this unique continental margin: The IGUANES cruise, let by the University of Perpignan, took place in April/May 2013, using a higher resolution multibeam echosounder, high resolution seismic reflection and sediment cores. In particular we were able to confirm and better map significant submarine landslide scarps, aligned pockmark fields and sediment waves that likely associated with strong bottom currents and/or the submarine landslides. We will also briefly describe some of the highlight results of other ECS related cruises to show how the EXTRAPLAC program has resulted in new knowledge in remote frontier areas that had very little modern data coverage.

  20. Thermal and electrical conductivity of iron at Earth's core conditions.

    PubMed

    Pozzo, Monica; Davies, Chris; Gubbins, David; Alfè, Dario

    2012-05-17

    The Earth acts as a gigantic heat engine driven by the decay of radiogenic isotopes and slow cooling, which gives rise to plate tectonics, volcanoes and mountain building. Another key product is the geomagnetic field, generated in the liquid iron core by a dynamo running on heat released by cooling and freezing (as the solid inner core grows), and on chemical convection (due to light elements expelled from the liquid on freezing). The power supplied to the geodynamo, measured by the heat flux across the core-mantle boundary (CMB), places constraints on Earth's evolution. Estimates of CMB heat flux depend on properties of iron mixtures under the extreme pressure and temperature conditions in the core, most critically on the thermal and electrical conductivities. These quantities remain poorly known because of inherent experimental and theoretical difficulties. Here we use density functional theory to compute these conductivities in liquid iron mixtures at core conditions from first principles--unlike previous estimates, which relied on extrapolations. The mixtures of iron, oxygen, sulphur and silicon are taken from earlier work and fit the seismologically determined core density and inner-core boundary density jump. We find both conductivities to be two to three times higher than estimates in current use. The changes are so large that core thermal histories and power requirements need to be reassessed. New estimates indicate that the adiabatic heat flux is 15 to 16 terawatts at the CMB, higher than present estimates of CMB heat flux based on mantle convection; the top of the core must be thermally stratified and any convection in the upper core must be driven by chemical convection against the adverse thermal buoyancy or lateral variations in CMB heat flow. Power for the geodynamo is greatly restricted, and future models of mantle evolution will need to incorporate a high CMB heat flux and explain the recent formation of the inner core. PMID:22495307

  1. The evolving science of detection of ‘blood doping’

    PubMed Central

    Lundby, Carsten; Robach, Paul; Saltin, Bengt

    2012-01-01

    Blood doping practices in sports have been around for at least half a century and will likely remain for several years to come. The main reason for the various forms of blood doping to be common is that they are easy to perform, and the effects on exercise performance are gigantic. Yet another reason for blood doping to be a popular illicit practice is that detection is difficult. For autologous blood transfusions, for example, no direct test exists, and the direct testing of misuse with recombinant human erythropoietin (rhEpo) has proven very difficult despite a test exists. Future blood doping practice will likely include the stabilization of the transcription factor hypoxia-inducible factor which leads to an increased endogenous erythropoietin synthesis. It seems unrealistic to develop specific test against such drugs (and the copies hereof originating from illegal laboratories). In an attempt to detect and limit blood doping, the World Anti-Doping Agency (WADA) has launched the Athlete Biological Passport where indirect markers for all types of blood doping are evaluated on an individual level. The approach seemed promising, but a recent publication demonstrates the system to be incapable of detecting even a single subject as ‘suspicious’ while treated with rhEpo for 10–12 weeks. Sad to say, the hope that the 2012 London Olympics should be cleaner in regard to blood doping seems faint. We propose that WADA strengthens the quality and capacities of the National Anti-Doping Agencies and that they work more efficiently with the international sports federations in an attempt to limit blood doping. PMID:22225538

  2. Convective storms in planetary atmospheres

    NASA Astrophysics Data System (ADS)

    Hueso, R.; Sánchez-Lavega, A.

    2013-05-01

    The atmospheres of the planets in the Solar System have different physical properties that in some cases can be considered as extreme when compared with our own planet's more familiar atmosphere. From the tenuous and cold atmosphere of Mars to the dense and warm atmosphere of Venus in the case of the terrestrial planets, to the gigantic atmospheres of the outer planets, or the nitrogen and methane atmosphere of Saturn's moon Titan, we can find a large variety of physical environments. The comparative study of these atmospheres provides a better understanding of the physics of a geophysical fluid. In many of these worlds convective storms of different intensity appear. They are analogous to terrestrial atmospheres fed by the release of latent heat when one of the gases in the atmosphere condenses and they are therefore called moist convective storms. In many of these planets they can produce severe meteorological phenomena and by studying them in a comparative way we can aspire to get a further insight in the dynamics of these atmospheres even beyond the scope of moist convection. A classical example is the structure of the complex systems of winds in the giant planets Jupiter and Saturn. These winds are zonal and alternate in latitude but their deep structure is not accessible to direct observation. However the behaviour of large--scale convective storms vertically extending over the "weather layer" allows to study the buried roots of these winds. Another interesting atmosphere with a rather different structure of convection is Titan, a world where methane is close to its triple point in the atmosphere and can condense in bright clouds with large precipitation fluxes that may model part of the orography of the surface making Titan a world with a methane cycle similar to the hydrological cycle of Earth's atmosphere.

  3. Earth after the Moon-forming Impact

    NASA Technical Reports Server (NTRS)

    Zahnle, K. J.

    2006-01-01

    The Hadean Earth is widely and enduringly pictured as a world of exuberant volcanism, exploding meteors, huge craters, infernal heat, and billowing sulfurous steams; i.e., a world of fire and brimstone punctuated with blows to the head. In the background the Moon looms gigantic in the sky. The popular image has given it a name that celebrates our mythic roots. A hot early Earth is an inevitable consequence of accretion. The Moon-forming impact ensured that Earth as we know it emerged from a fog of silicate vapor. The impact separated the volatiles from the silicates. It took approx. 100 years to condense and rain out the bulk of the vaporized silicates, although relatively volatile elements may have remained present in the atmosphere throughout the magma ocena stage. The magma ocean lasted approx. 2 Myr, its lifetime prolonged by tidal heating and thermal blanketing by a thick CO2-rich steam atmosphere. Water oceans condensed quickly after the mantle solidified, but for some 10-100 Myr the surface would have stayed warm (approx. 500 K) until the CO2 was removed into the mantle. Thereafter the faint young Sun suggests that a lifeless Earth would always have been evolving toward a bitterly cold ice world, but the cooling trend was fiequently interrupted by volcanic or impact induced thaws. A cartoon history of water, temperature, and carbon dioxide in the aftermath of the moon-formining-impact is shown. How long it stays hot depends on how long it takes to scrub the C02 out of the atmosphere.

  4. Rhodolith beds are major CaCO3 bio-factories in the tropical South West Atlantic.

    PubMed

    Amado-Filho, Gilberto M; Moura, Rodrigo L; Bastos, Alex C; Salgado, Leonardo T; Sumida, Paulo Y; Guth, Arthur Z; Francini-Filho, Ronaldo B; Pereira-Filho, Guilherme H; Abrantes, Douglas P; Brasileiro, Poliana S; Bahia, Ricardo G; Leal, Rachel N; Kaufman, Les; Kleypas, Joanie A; Farina, Marcos; Thompson, Fabiano L

    2012-01-01

    Rhodoliths are nodules of non-geniculate coralline algae that occur in shallow waters (<150 m depth) subjected to episodic disturbance. Rhodolith beds stand with kelp beds, seagrass meadows, and coralline algal reefs as one of the world's four largest macrophyte-dominated benthic communities. Geographic distribution of rhodolith beds is discontinuous, with large concentrations off Japan, Australia and the Gulf of California, as well as in the Mediterranean, North Atlantic, eastern Caribbean and Brazil. Although there are major gaps in terms of seabed habitat mapping, the largest rhodolith beds are purported to occur off Brazil, where these communities are recorded across a wide latitudinal range (2°N-27°S). To quantify their extent, we carried out an inter-reefal seabed habitat survey on the Abrolhos Shelf (16°50'-19°45'S) off eastern Brazil, and confirmed the most expansive and contiguous rhodolith bed in the world, covering about 20,900 km(2). Distribution, extent, composition and structure of this bed were assessed with side scan sonar, remotely operated vehicles, and SCUBA. The mean rate of CaCO(3) production was estimated from in situ growth assays at 1.07 kg m(-2) yr(-1), with a total production rate of 0.025 Gt yr(-1), comparable to those of the world's largest biogenic CaCO(3) deposits. These gigantic rhodolith beds, of areal extent equivalent to the Great Barrier Reef, Australia, are a critical, yet poorly understood component of the tropical South Atlantic Ocean. Based on the relatively high vulnerability of coralline algae to ocean acidification, these beds are likely to experience a profound restructuring in the coming decades. PMID:22536356

  5. Rhodolith Beds Are Major CaCO3 Bio-Factories in the Tropical South West Atlantic

    PubMed Central

    Amado-Filho, Gilberto M.; Moura, Rodrigo L.; Bastos, Alex C.; Salgado, Leonardo T.; Sumida, Paulo Y.; Guth, Arthur Z.; Francini-Filho, Ronaldo B.; Pereira-Filho, Guilherme H.; Abrantes, Douglas P.; Brasileiro, Poliana S.; Bahia, Ricardo G.; Leal, Rachel N.; Kaufman, Les; Kleypas, Joanie A.; Farina, Marcos; Thompson, Fabiano L.

    2012-01-01

    Rhodoliths are nodules of non-geniculate coralline algae that occur in shallow waters (<150 m depth) subjected to episodic disturbance. Rhodolith beds stand with kelp beds, seagrass meadows, and coralline algal reefs as one of the world's four largest macrophyte-dominated benthic communities. Geographic distribution of rhodolith beds is discontinuous, with large concentrations off Japan, Australia and the Gulf of California, as well as in the Mediterranean, North Atlantic, eastern Caribbean and Brazil. Although there are major gaps in terms of seabed habitat mapping, the largest rhodolith beds are purported to occur off Brazil, where these communities are recorded across a wide latitudinal range (2°N - 27°S). To quantify their extent, we carried out an inter-reefal seabed habitat survey on the Abrolhos Shelf (16°50? - 19°45?S) off eastern Brazil, and confirmed the most expansive and contiguous rhodolith bed in the world, covering about 20,900 km2. Distribution, extent, composition and structure of this bed were assessed with side scan sonar, remotely operated vehicles, and SCUBA. The mean rate of CaCO3 production was estimated from in situ growth assays at 1.07 kg m?2 yr?1, with a total production rate of 0.025 Gt yr?1, comparable to those of the world's largest biogenic CaCO3 deposits. These gigantic rhodolith beds, of areal extent equivalent to the Great Barrier Reef, Australia, are a critical, yet poorly understood component of the tropical South Atlantic Ocean. Based on the relatively high vulnerability of coralline algae to ocean acidification, these beds are likely to experience a profound restructuring in the coming decades. PMID:22536356

  6. Towards to Creation Unit Theory Oil Generation

    NASA Astrophysics Data System (ADS)

    Galant, Yuri

    2014-05-01

    Creating a unified theory of the genesis of oil encompasses all aspects of oil's life beginning from the formation the chemical elements. Globally, in the spatio-temporal aspect oil's life covers a Cosmic (pre geological) stage and geologically stage of formation of the planet Earth. In conces of spatio-temporal aspect unified theory of oil formation is based on the sequence of occurrences of chemical elements from which to create the Planet Earth and its Granite and Basalt Domains. From this standpoint is an independent Oil Domain along with Granite and Basalt. Sequence analysis of the appearance of chemical elements (H, C, N, O, Na, Mg, Al, Si, K, Ca, Ti, Fe, etc.) reveals the genesis of oil at a very early stage of the creation of Earth according appearance first of H and C. Next, according to the sequence of appearance (creation) of the elements are formed of Granite and Basalt Domain. The appearance of: (chemical element - serial number of) H 1, O 8 corresponds to the appearance of the aqueous layer. The appearance of Na 11, Al 13, Si 14 corresponds to the appearance of the Granite layer. The appearance of Ca 20, Fe 26 corresponds to the appearance of the Basalt layer. The process of formation of domains continues to today. Currently, Oil Domain encircles Globe on the south and north and manifests itself from micro quantities to gigantic clusters. In the formation of unit oil involves various methods involving initial elements C and H of various geneses. A unity of theory of oil generation in her polygenic !

  7. Hellbender Genome Sequences Shed Light on Genomic Expansion at the Base of Crown Salamanders

    PubMed Central

    Sun, Cheng; Mueller, Rachel Lockridge

    2014-01-01

    Among animals, genome sizes range from 20 Mb to 130 Gb, with 380-fold variation across vertebrates. Most of the largest vertebrate genomes are found in salamanders, an amphibian clade of 660 species. Thus, salamanders are an important system for studying causes and consequences of genomic gigantism. Previously, we showed that plethodontid salamander genomes accumulate higher levels of long terminal repeat (LTR) retrotransposons than do other vertebrates, although the evolutionary origins of such sequences remained unexplored. We also showed that some salamanders in the family Plethodontidae have relatively slow rates of DNA loss through small insertions and deletions. Here, we present new data from Cryptobranchus alleganiensis, the hellbender. Cryptobranchus and Plethodontidae span the basal phylogenetic split within salamanders; thus, analyses incorporating these taxa can shed light on the genome of the ancestral crown salamander lineage, which underwent expansion. We show that high levels of LTR retrotransposons likely characterize all crown salamanders, suggesting that disproportionate expansion of this transposable element (TE) class contributed to genomic expansion. Phylogenetic and age distribution analyses of salamander LTR retrotransposons indicate that salamanders’ high TE levels reflect persistence and diversification of ancestral TEs rather than horizontal transfer events. Finally, we show that relatively slow DNA loss rates through small indels likely characterize all crown salamanders, suggesting that a decreased DNA loss rate contributed to genomic expansion at the clade’s base. Our identification of shared genomic features across phylogenetically distant salamanders is a first step toward identifying the evolutionary processes underlying accumulation and persistence of high levels of repetitive sequence in salamander genomes. PMID:25115007

  8. New insights into regional tectonics of the Indochina Peninsula inferred from Lower-Middle Jurassic paleomagnetic data of the Sibumasu Terrane

    NASA Astrophysics Data System (ADS)

    Fujiwara, Katsuya P.; Zaman, Haider; Surinkum, Adichat; Chaiwong, Nikhom; Fujihara, Makoto; Ahn, Hyeon-Seon; Otofuji, Yo-ichiro

    2014-11-01

    The post-Jurassic occurrence of differential tectonic rotation between the Indochina and South Sundaland blocks remains an issue to be properly investigated. New paleomagnetic study is used here to find the role of Sibumasu Terrane in this rotation, which is located between a clockwise rotated Indochina Block and a counter-clockwise rotated South Sundaland Block. For this purpose, lower to middle Jurassic red sandstones of the Umphang Group in the Sibumasu Terrane were sampled at 21 sites in the Ratchaburi area (13.6°E, 99.6°E), Thailand. Stepwise thermal demagnetization by 680 °C unblocked a pre-folding characteristic remanent magnetization. A mean direction of this component at 100% unfolding is Ds = 348.5°, Is = 24.7°, ?95 = 10.5°, k = 10.7, N = 20, corresponding to an Early-Middle Jurassic pole of ? = 78.6°N, ? = 10.6°E (A95 = 9.3). Comparison of this direction with those reported from other localities of the Umphang Group (Kalaw, Mae Sot and North Trang Syncline localities) reveal variable declinations (between 348.5° and 44.7°) for the Sibumasu Terrane. We ascribe this variation to differential tectonic deformation in the Sibumasu Terrane, as reflected from sinusoidal shaped structural features in the study area. The presence of such features in the granitic rocks indicates the occurrences of deformational activities after their intrusion, which took place in the period between 130 Ma and 51 Ma. The Sibumasu Terrane behaved as an independent fragment at a time when Indochina was undergoing a clockwise rotation and southward displacement, as a result of extrusion tectonics after the gigantic India-Asia collision. Taking into consideration a westerly deflected declination (D = 342.8°) from the West Trang area in Peninsular Thailand, a counterclockwise rotation of 15° is estimated for the Sibumasu Terrane, as a result of continuous northward indentation of the Australian Plate into South Sundaland Block.

  9. Familial Isolated Pituitary Adenomas (FIPA) and the Pituitary Adenoma Predisposition due to Mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene

    PubMed Central

    Aaltonen, Lauri A.; Daly, Adrian F.

    2013-01-01

    Pituitary adenomas are one of the most frequent intracranial tumors and occur with a prevalence of approximately 1:1000 in the developed world. Pituitary adenomas have a serious disease burden, and their management involves neurosurgery, biological therapies, and radiotherapy. Early diagnosis of pituitary tumors while they are smaller may help increase cure rates. Few genetic predictors of pituitary adenoma development exist. Recent years have seen two separate, complimentary advances in inherited pituitary tumor research. The clinical condition of familial isolated pituitary adenomas (FIPA) has been described, which encompasses the familial occurrence of isolated pituitary adenomas outside of the setting of syndromic conditions like multiple endocrine neoplasia type 1 and Carney complex. FIPA families comprise approximately 2% of pituitary adenomas and represent a clinical entity with homogeneous or heterogeneous pituitary adenoma types occurring within the same kindred. The aryl hydrocarbon receptor interacting protein (AIP) gene has been identified as causing a pituitary adenoma predisposition of variable penetrance that accounts for 20% of FIPA families. Germline AIP mutations have been shown to associate with the occurrence of large pituitary adenomas that occur at a young age, predominantly in children/adolescents and young adults. AIP mutations are usually associated with somatotropinomas, but prolactinomas, nonfunctioning pituitary adenomas, Cushing disease, and other infrequent clinical adenoma types can also occur. Gigantism is a particular feature of AIP mutations and occurs in more than one third of affected somatotropinoma patients. Study of pituitary adenoma patients with AIP mutations has demonstrated that these cases raise clinical challenges to successful treatment. Extensive research on the biology of AIP and new advances in mouse Aip knockout models demonstrate multiple pathways by which AIP may contribute to tumorigenesis. This review assesses the current clinical and therapeutic characteristics of more than 200 FIPA families and addresses research findings among AIP mutation-bearing patients in different populations with pituitary adenomas. PMID:23371967

  10. Protection of Cities from Small Rockets, Missiles, Projectiles and Mortar Shells

    E-print Network

    Alexander Bolonkin; Joseph Friedlander

    2008-02-03

    The authors suggest a low cost closed AB-Dome, which may protect small cities such as Sederot from rockets, mortar shells, chemical and biological weapons. The offered AB-Dome is also very useful in peacetime because it protects the city from outside weather (violent storms, hail) and creates a fine climate within the Dome. The roughly hemispherical AB-Dome is a gigantic inflated thin transparent film, located at altitude up to 1 - 5 kilometers, which converts the city into a closed-loop air system. The film may be armored with a basalt or steel grille or cloth pocket-retained stones that destroy (by collision or detonation) incoming rockets, shells and other projectiles. Such an AB-Dome would even protect the city in case of a third-party nuclear war involving temporary poisoning of the Earth atmosphere by radioactive dust. The building of the offered dome is easy; the film spreads on the ground, the fan engines turn on and the cover rises to the needed altitude and is supported there by a small internal overpressure. The offered method is cheaper by thousands of times than protection of a city by current anti-rocket systems. The AB-Dome may be also used (height is up to 1-5 and more kilometers) for TV, communication, long distance location, tourism, suspended high speed and altitude windmills (energy), illumination and entertainment (projected messages and pictures). The authors developed the theory of AB-Dome, made estimations, computations and computed a typical project. Discussion and results are at the end of the article.

  11. Nitrogen in Solar System Minor Bodies: Delivery Pathways to Primeval Earth

    NASA Astrophysics Data System (ADS)

    Trigo-Rodríguez, Josep M.

    Oxygen isotope data point towards enstatite and ordinary chondrites as presumable building blocks of primordial Earth. Nitrogen was incorporated as nitrides to these first building blocks and was outgassed in the early stages of chemical segregation. However, giant impacts with planetesimals played an important role in partially eroding the atmosphere of Earth, and promoting thermal escape of diverse components. As a consequence, the Earth's atmospheric composition could have been subjected to important changes along the eons. A last, and probably less massive, delivery of volatiles took place at the time of a gigantic cataclysm known as Late Heavy Bombardment. During a short interval roughly between 3.9 and 3.8 Gyr ago, a gravitational migration inwards of Jupiter and Saturn occurred, that perturbed hundreds of small bodies rich in water, ammonia, methane and organic compounds that were stored until then in the outer regions. Current atmospheric signatures suggest that by that mechanism a continuous shower of outer-disk primordial components enriched the volatile inventory of terrestrial planets. The relevance of such contribution is still debated, but significant progress has been made in the last decades from the study of undifferentiated bodies. Consequently, planetary scattering of undifferentiated bodies delivered to Earth a significant fraction of minerals, and light elements that could have played a key role in the volatile enrichment the terrestrial crust. I suggest some unexplored pathways to allow a safe delivery of organics to Earth's surface, following recent evidence on meteoroid fragmentation, fireball spectra and Antarctic micrometeorite discoveries. Recent compositional studies of asteroids, comets and meteorites corroborate the need of having more precise data on the abundance and isotopic ratios of N in these minor bodies. Future space missions to primitive bodies like Rosetta, OSIRIS-Rex, Hayabusa II, or Marco Polo-R could help us to complete the big picture, and this chapter tries to compile our present knowledge of its delivery to Earth along the eons.

  12. The Magellanic Stream System. I. Ram-Pressure Tails and the Relics of the Collision Between the Magellanic Clouds

    NASA Astrophysics Data System (ADS)

    Hammer, F.; Yang, Y. B.; Flores, H.; Puech, M.; Fouquet, S.

    2015-11-01

    We have analyzed the Magellanic Stream (MS) using the deepest and the most resolved H i survey of the Southern Hemisphere (the Galactic All-Sky Survey). The overall Stream is structured into two filaments, suggesting two ram-pressure tails lagging behind the Magellanic Clouds (MCs), and resembling two close, transonic, von Karman vortex streets. The past motions of the Clouds appear imprinted in them, implying almost parallel initial orbits, and then a radical change after their passage near the N(H i) peak of the MS. This is consistent with a recent collision between the MCs, 200–300 Myr ago, which has stripped their gas further into small clouds, spreading them out along a gigantic bow shock, perpendicular to the MS. The Stream is formed by the interplay between stellar feedback and the ram pressure exerted by hot gas in the Milky Way (MW) halo with nh = 10?4 cm?3 at 50–70 kpc, a value necessary to explain the MS multiphase high-velocity clouds. The corresponding hydrodynamic modeling provides the currently most accurate reproduction of the whole H i Stream morphology, of its velocity, and column density profiles along LMS. The “ram pressure plus collision” scenario requires tidal dwarf galaxies, which are assumed to be the Cloud and dSph progenitors, to have left imprints in the MS and the Leading Arm, respectively. The simulated LMC and SMC have baryonic mass, kinematics, and proper motions consistent with observations. This supports a novel paradigm for the MS System, which could have its origin in material expelled toward the MW by the ancient gas-rich merger that formed M31.

  13. Testing the 'island rule' for a tenebrionid beetle (Coleoptera, Tenebrionidae)

    NASA Astrophysics Data System (ADS)

    Palmer, Miquel

    2002-05-01

    Insular populations and their closest mainland counterparts commonly display body size differences that are considered to fit the island rule, a theoretical framework to explain both dwarfism and gigantism in isolated animal populations. The island rule is used to explain the pattern of change of body size at the inter-specific level. But the model implicitly makes also a prediction for the body size of isolated populations of a single species. It suggests that, for a hypothetical species covering a wide range of island sizes, there exists a specific island size where this species reaches the largest body size. Body size would be small (in relative terms) in the smallest islets of the species range. It would increase with island size, and reach a maximum at some specific island size. However, additional increases from such a specific island size would instead promote body size reduction, and small (in relative terms) body sizes would be found again on the largest islands. The biogeographical patterns predicted by the island rule have been described and analysed for vertebrates only (mainly mammals), but remain largely untested for insects or other invertebrates. I analyse here the pattern of body size variation between seven isolated insular populations of a flightless beetle, Asida planipennis (Coleoptera, Tenebrionidae). This is an endemic species of Mallorca, Menorca and a number of islands and islets in the Balearic archipelago (western Mediterranean). The study covers seven of the 15 known populations (i.e., there are only 15 islands or islets inhabited by the species). The populations studied fit the pattern advanced above and we could, therefore, extrapolate the island rule to a very different kind of organism. However, the small sample size of some of the populations invites some caution at this early stage.

  14. Prevalence and Risk Factors for Depressive Reaction among Resident Survivors after the Tsunami following the Great East Japan Earthquake, March 11, 2011

    PubMed Central

    Matsubara, Chieko; Murakami, Hitoshi; Imai, Koubun; Mizoue, Tetsuya; Akashi, Hidechika; Miyoshi, Chiaki; Nakasa, Tamotsu

    2014-01-01

    Objectives The Great East Japan Earthquake caused a gigantic tsunami which devastated coastal areas of northern Japan on 11 March 2011. Despite the large number of ‘resident survivors’ who continued to reside in their damaged houses on the second or upper floors, research on the mental health of these individuals has been limited. This study explored the prevalence of depressive reaction and risk factors for depressive reaction among these resident survivors. Methods A cross-sectional household health support needs screening was conducted for resident survivors in Higashi-Matsushima city, Miyagi prefecture, two to four months after the tsunami. The health interview that was conducted including mental status, assessed by the Patient Health Questionnaire-2 (PHQ-2). Results Of 5,454 respondents, 8.1% had depressive reaction. After adjustment by the number of weeks from the tsunami and the mortality rate at each respondent's place of residence, depressive reaction was significantly associated with house flooding below or above the ground floor (odds ratios of 1.92, 2.36, respectively), the unavailability of gas supply (odds ratio, 1.67), being female (odds ratio, 1.47), middle aged or elderly (odds ratios of 2.41, 2.42, respectively), regular intake of psychotropic medicine(s) since before the tsunami (odds ratio, 2.53) and the presence of one to five or more than six cohabiters (odds ratios of 0.61, 0.52, respectively). Conclusions The results suggest a considerable psychological burden (depressive reaction) following the tsunami among resident survivors. Special supports for families with psychiatric problems need to be considered among resident survivors. Restoration of lifeline utilities and the strengthening of social ties of persons living alone may help prevent depressive reaction among resident survivors after a tsunami. PMID:25279563

  15. Twisting Tourniquet(©) Technique: introducing Schnogh, a novel device and its effectiveness in treating primary and secondary lymphedema of extremities.

    PubMed

    Chanwimalueang, Narumon; Ekataksin, Wichai; Piyaman, Parkpoom; Pattanapen, Gedsuda; Hanboon, Borimas K

    2015-10-01

    Twisting Tourniquet(©) or in Thai "Schnogh" is a new invention for compression therapy of lymphedema. Twisting Tourniquet(©) Technique (TTT) is totally noninvasive for lymphedema management. After the amazing successful evidence in the first series of 28 patients, we have conducted preliminary studies in lymphedema clinics. It was found that the combination of gradually increasing constriction force by Schnogh until desired pressure was reached and maintained for 15 min, followed by a 5-min release, doing repeatedly this compression-decompression for at least 10 sessions a day, can generate acceptable results. The aim of the study was to evaluate the scientific effectiveness and establish a treatment protocol of TTT proposed as a therapeutic approach for clinical management of lymphedema. During 2006-2013, from over 3500 patients, 647 with primary/secondary lymphedema passed inclusion criteria, 307 for upper, and 340 for lower extremity. In the 5-day course of TTT, each day patients underwent 10 sessions of a 15-min compression followed by a 5-min decompression. Vegan diet was encouraged as an adjuvant therapy. Among lymphedema patients whose spectrum of edema severity ranged from mild to gigantic, TTT yielded an average volume reduction rate (VR) at 50.2% and 55.6%, making the average edema reduction volume attained at 463 and 1856 mL for upper and lower limb, respectively. The uniformed practice by Schnogh which supports a continual compression-decompression maneuver over 3.5 h daily for five consecutive days could induce an average VR at above half of the swelling in extremities of 647 patients. Schnogh is therefore effective in clinical management of lymphedema under TTT treatment of fibroblastic interstitium. PMID:26247407

  16. [IT network establishment for neuropatients].

    PubMed

    Abe, Koji; Uchiyama, Shinichiro; Matsubara, Etsuro; Muramatsu, Shin-Ichi; Atsuta, Naoki; Kitagawa, Kazuo; Iguchi, Yasuyuki; Ooboshi, Hiroaki; Kaji, Ryuji; Terao, Yasuo

    2013-01-01

    On March 11, 2011, big earthquake and subsequent gigantic tsunami killed more than 20,000 peoples in Tohoku area of Japan. Neurological patients were one such victim because they are usually very vulnerable to such a huge tragedy due to their physical disability including artificial ventilator-support. On occasion of the last tsunami, most cases showed "all or nothing" to lose life or to survive, and there were only a little cases who needed emergency surgical treatment. In the very early period, some neurological patients required electric power to keep their lifesupportive ventilator at evacuation house or even at home. In a week to a couple of months, many neurological patients needed continuous supply of their daily drugs which are essential to keep themselves in steady physical conditions and even for keeping their life.Japanese Neurological Society (JNS) began to establish an emergent assistant network system from January 2012 in an attempt of supplying materials, drugs and energy power to neurological patients who require both under a very early period after any natural or political disaster and a later period. For example, JNS is going to apply IT system to connect distant but safer hospitals which accept emergent patients from the center of disastrous place. JNS may also send emergency medical team to the disastrous place to save neurological patients by passing necessary medicine and materials or moving patients to safer hospitals. JNS will make such a tentative program public on our website to collect many other constructive opinions from general member of the society and neurological patients. After getting those opinions, JNS made up the exact team for this purpose after general meeting of JNS on this May 2012.Based on this team, disaster-mimic trial will be performed in Tokyo, Shizuoka, and Kochi where the next big disaster is going to hit the cities. PMID:24291913

  17. [Rescue system establishment for neurological patients in case of natural disastrous emergency].

    PubMed

    Abe, Koji

    2012-01-01

    Big earthquake and subsequent gigantic tsunami killed more than 20,000 peoples in Tohoku area of Japan on March 11, 2011. Neurological patients were one such victim because they are usually very vulnerable to such a huge tragedy due to their physical disability including artificial ventilator-support. On occasion of the last tsunami, most cases showed "all or nothing" to lose life or to survive, and there were only a little cases who needed emergency surgical treatment. In the very early period, some neurological patients required electric power to keep their life-supportive ventilator at evacuation house or even at home. In a week to a couple of months, many neurological patients needed continuous supply of their daily drugs which are essential to keep themselves in steady physical conditions and even for keeping their life. Based on such a background, Japanese Neurological Society (JNS) began to establish an emergent assistant network system from January 2012 in an attempt of supplying materials, drugs and energy power to neurological patients who require both under a very early period after any natural or political disaster and a later period. For example, JNS is going to apply IT system to connect distant but safer hospitals which accept emergent patients from the center of disastrous place. JNS may also send emergency medical team to the disastrous place to save neurological patients by passing necessary medicine and materials or moving patients to safer hospitals. JNS will make such a tentative program public on our website to collect many other constructive opinions from general member of the society and neurological patients. After getting those opinions, JNS will work to make the exact team for this purpose after general meeting of JNS on this May 2012. PMID:23196614

  18. The mystical effects of dermatological vehicles.

    PubMed

    Surber, Christian; Smith, Eric W

    2005-01-01

    Topical treatment of the skin is as old as the evolution of man. Instinctively, we try to treat a skin injury or irritation with cooling or soothing substances. Even animals lick their wounds, trusting instinctively in the healing power of saliva. When did this archaic pattern of treatment take the gigantic leap from folk medicine to modern drug therapy? This text illustrates the evolution of topical dermatological vehicles, their application (guidelines) and future use. In particular, a phenomenon that has so far been ignored in product development and clinical testing is the vehicle metamorphosis. In clinical and experimental situations, most dermatological vehicles undergo considerable changes after they have been removed from the primary container and are applied to the skin. Subsequently, the initial structural matrix, and the quantitative composition of the vehicle, will most likely change during and after the mechanical shear associated with application of the product and/or evaporation of ingredients. This natural, but highly dynamic process will generate mini-environments for the active moiety that are difficult to predict and that are crucial to the fate of the active moiety. Despite the reasonable wishes of formulators, clinicians, patients and customers, there are still no universal vehicles. Each drug, at each concentration, requires a different vehicle for optimized therapy. Stability and compatibility of excipients and active moiety are crucial for any commercially available pharmaceutical or cosmetic formulation, together with local and systemic safety of all components. Nonetheless, more diverse and molecularly complex classes of new dermatological vehicles are continuously being researched and refined. The scientific progress has been remarkable when one considers the simple emulsion mixtures that were commonplace in dermatological therapy and still persist to this day in commercial products. It is to be hoped that the result of these research endeavors will be the emergence of more innovative topical formulations, applying engineered bioavailability control systems, with broader applications in topical therapeutic and cosmetic vehicles. PMID:15724099

  19. Status of Solar Sail Propulsion Within NASA - Moving Toward Interstellar Travel

    NASA Technical Reports Server (NTRS)

    Johnson, Les

    2015-01-01

    NASA is developing solar sail propulsion for two near-term missions and laying the groundwork for their future use in deep space and interstellar precursor missions. Solar sails use sunlight to propel vehicles through space by reflecting solar photons from a large, mirror-like sail made of a lightweight, highly reflective material. This continuous photon pressure provides propellantless thrust, allowing for very high (Delta)V maneuvers on long-duration, deep space exploration. Since reflected light produces thrust, solar sails require no onboard propellant. The Near Earth Asteroid (NEA) Scout mission, managed by MSFC, will use the sail as primary propulsion allowing it to survey and image one or more NEA's of interest for possible future human exploration. Lunar Flashlight, managed by JPL, will search for and map volatiles in permanently shadowed Lunar craters using a solar sail as a gigantic mirror to steer sunlight into the shaded craters. The Lunar Flashlight spacecraft will also use the propulsive solar sail to maneuver into a lunar polar orbit. Both missions use a 6U cubesat architecture, a common an 85 sq m solar sail, and will weigh less than 12 kilograms. Both missions will be launched on the first flight of the Space Launch System in 2018. NEA Scout and Lunar Flashlight will serve as important milestones in the development of solar sail propulsion technology for future, more ambitious missions including the Interstellar Probe - a mission long desired by the space science community which would send a robotic probe beyond the edge of the solar system to a distance of 250 Astronomical Units or more. This paper will summarize the development status of NEA Scout and Lunar Flashlight and describe the next steps required to enable an interstellar solar sail capability.

  20. Comparative Transcriptome Profiling of the Early Response to Magnaporthe oryzae in Durable Resistant vs Susceptible Rice (Oryza sativa L.) Genotypes

    PubMed Central

    Bagnaresi, Paolo; Biselli, Chiara; Orrù, Luigi; Urso, Simona; Crispino, Laura; Abbruscato, Pamela; Piffanelli, Pietro; Lupotto, Elisabetta; Cattivelli, Luigi; Valè, Giampiero

    2012-01-01

    Durable resistance to blast, the most significant fungal disease of rice, represents an agronomically relevant character. Gigante Vercelli (GV) and Vialone Nano (VN) are two old temperate japonica Italian rice cultivars with contrasting response to blast infection: GV displays durable and broad resistance while VN is highly susceptible. RNA-seq was used to dissect the early molecular processes deployed during the resistance response of GV at 24 h after blast inoculation. Differential gene expression analysis identified 1,070 and 1,484 modulated genes, of which 726 and 699 were up regulated in response to infection in GV and VN, respectively. Gene ontology (GO) enrichment analyses revealed a set of GO terms enriched in both varieties but, despite this commonality, the gene sets contributing to common GO enriched terms were dissimilar. The expression patterns of genes grouped in GV-specific enriched GO terms were examined in detail including at the transcript isoform level. GV exhibited a dramatic up-regulation of genes encoding diterpene phytoalexin biosynthetic enzymes, flavin-containing monooxygenase, class I chitinase and glycosyl hydrolase 17. The sensitivity and high dynamic range of RNA-seq allowed the identification of genes critically involved in conferring GV resistance during the early steps of defence perception-signalling. These included chitin oligosaccharides sensing factors, wall associated kinases, MAPK cascades and WRKY transcription factors. Candidate genes with expression patterns consistent with a potential role as GV-specific functional resistance (R) gene(s) were also identified. This first application of RNA-seq to dissect durable blast resistance supports a crucial role of the prompt induction of a battery of responses including defence-related genes as well as members of gene families involved in signalling and pathogen-related gene expression regulation. PMID:23251593

  1. The water balance components of undisturbed tropical woodlands in the Brazilian cerrado

    NASA Astrophysics Data System (ADS)

    Oliveira, P. T. S.; Wendland, E.; Nearing, M. A.; Scott, R. L.; Rosolem, R.; da Rocha, H. R.

    2015-06-01

    Deforestation of the Brazilian cerrado region has caused major changes in hydrological processes. These changes in water balance components are still poorly understood but are important for making land management decisions in this region. To better understand pre-deforestation conditions, we determined the main components of the water balance for an undisturbed tropical woodland classified as "cerrado sensu stricto denso". We developed an empirical model to estimate actual evapotranspiration (ET) by using flux tower measurements and vegetation conditions inferred from the enhanced vegetation index and reference evapotranspiration. Canopy interception, throughfall, stemflow, surface runoff, and water table level were assessed from ground measurements. We used data from two cerrado sites, Pé de Gigante (PDG) and Instituto Arruda Botelho (IAB). Flux tower data from the PDG site collected from 2001 to 2003 were used to develop the empirical model to estimate ET. The other hydrological processes were measured at the field scale between 2011 and 2014 at the IAB site. The empirical model showed significant agreement (R2 = 0.73) with observed ET at the daily timescale. The average values of estimated ET at the IAB site ranged from 1.91 to 2.60 mm day-1 for the dry and wet seasons, respectively. Canopy interception ranged from 4 to 20 % and stemflow values were approximately 1 % of the gross precipitation. The average runoff coefficient was less than 1 %, while cerrado deforestation has the potential to increase that amount up to 20-fold. As relatively little excess water runs off (either by surface water or groundwater), the water storage may be estimated by the difference between precipitation and evapotranspiration. Our results provide benchmark values of water balance dynamics in the undisturbed cerrado that will be useful to evaluate past and future land-cover and land-use changes for this region.

  2. A Diminutive Volcano

    NASA Technical Reports Server (NTRS)

    2003-01-01

    [figure removed for brevity, see original site]

    Released 15 October 2003

    The small Tharsis volcano called Biblis Patera is nearly lost amongst its gigantic neighbors. With a height of less than 10,000 feet, it is even dwarfed by many volcanoes on Earth. The gaping caldera of Biblis Patera shows evidence for multiple episodes of collapse, producing the concentric topography seen in the image. Several slope streaks are visible, indicators of a more recent and much smaller form of collapse: avalanches of the dust that thickly mantles the terrain.

    Image information: VIS instrument. Latitude 2.3, Longitude 236.4 East (123.6 West). 19 meter/pixel resolution.

    Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.

    NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena.

  3. Late Palaeozoic to Triassic evolution of the Turan and Scythian platforms: The pre-history of the Palaeo-Tethyan closure

    NASA Astrophysics Data System (ADS)

    Natal'in, Boris A.; ?engör, A. M. Celâl

    2005-08-01

    A number of en échelon-arranged, southwest-facing arc fragments of Palaeozoic to Jurassic ages, sandwiched between two fairly straight east-northeast trending boundaries, constitute the basement of the Scythian and the Turan platforms located between the Laurasian and Tethyside units. They have until now largely escaped detection owing to extensive Jurassic and younger cover and the inaccessibility of the subsurface data to the international geological community. These units are separated from one another by linear/gently-curved faults of great length and steep dip. Those that are exposed show evidence of strike-slip motion. The arc units originally constituted parts of a single "Silk Road Arc" located somewhere south of the present-day central Asia for much of the Palaeozoic, although by the late Carboniferous they had been united into a continental margin arc south of the Tarim basin and equivalent units to the west and east. They were stacked into their present places in northern Afghanistan, Turkmenistan, Caucasus and the northern Black Sea by large-scale, right-lateral strike-slip coastwise transport along arc-slicing and arc-shaving strike-slip faults in the Triassic and medial Jurassic simultaneously with the subductive elimination of Palaeo-Tethys. This gigantic dextral zone ("the Silk Road transpression") was a trans-Eurasian structure and was active simultaneously with another, similar system, the Gornostaev keirogen and greatly distorted Eurasia. The late Palaeozoic to Jurassic internal deformation of the Dniepr-Donets aulacogen was also a part of the dextral strain in southern Europe. When the emplacement of the Scythian and Turan units was completed, the elimination of Palaeo-Tethys had also ended and Neo-Tethyan arcs were constructed atop their ruins, mostly across their southern parts. The western end of the great dextral zone that emplaced the Turan and Scythian units horsetails just east of north Dobrudja and a small component goes along the Tornquist-Teisseyre lineament.

  4. Familial acromegaly due to aryl hydrocarbon receptor-interacting protein (AIP) gene mutation in a Turkish cohort.

    PubMed

    Niyazoglu, Mutlu; Sayitoglu, Muge; Firtina, Sinem; Hatipoglu, Esra; Gazioglu, Nurperi; Kadioglu, Pinar

    2014-06-01

    Aryl hydrocarbon receptor-interacting protein (AIP) is associated with 15-20% of familial isolated pituitary adenomas and 50-80% of cases with AIP mutation exhibit a somatotropinoma. Herein we report clinical characteristics of a large family where AIP R304X variants have been identified. AIP mutation analysis was performed on a large (n = 52) Turkish family across six generations. Sella MRIs of 30 family members were obtained. Basal pituitary hormone levels were evaluated in 13 family members harboring an AIP mutation. Thirteen of 52 family members (25%) were found to have a heterozygous nonsense germline R304X mutation in the AIP gene. Seven of the 13 mutation carriers (53.8%) had current or previous history of pituitary adenoma. Of these 7 mutation carriers, all but one had somatotropinoma/somatolactotropinoma (85.7% of the pituitary adenomas). Of the 6 acromegaly patients with AIP mutation (F/M: 3/3) the mean age at diagnosis of acromegaly was 32 ± 10.3 years while the mean age of symptom onset was 24.8 ± 9.9 years. Three of the six (50%) acromegaly cases with AIP mutation within the family presented with a macroadenoma and none presented with gigantism. Biochemical disease control was achieved in 66.6% (4/6) of the mutation carriers with acromegaly after a mean follow-up period of 18.6 ± 17.6 years. Common phenotypic characteristics of familial pituitary adenoma or somatotropinoma due to AIP mutation vary between families or even between individuals within a family. PMID:23743763

  5. Phase transition transistors based on strongly-correlated materials

    NASA Astrophysics Data System (ADS)

    Nakano, Masaki

    2013-03-01

    The field-effect transistor (FET) provides electrical switching functions through linear control of the number of charges at a channel surface by external voltage. Controlling electronic phases of condensed matters in a FET geometry has long been a central issue of physical science. In particular, FET based on a strongly correlated material, namely ``Mott transistor,'' has attracted considerable interest, because it potentially provides gigantic and diverse electronic responses due to a strong interplay between charge, spin, orbital and lattice. We have investigated electric-field effects on such materials aiming at novel physical phenomena and electronic functions originating from strong correlation effects. Here we demonstrate electrical switching of bulk state of matter over the first-order metal-insulator transition. We fabricated FETs based on VO2 with use of a recently developed electric-double-layer transistor technique, and found that the electrostatically induced carriers at a channel surface drive all preexisting localized carriers of 1022 cm-3 even inside a bulk to motion, leading to bulk carrier delocalization beyond the electrostatic screening length. This non-local switching of bulk phases is achieved with just around 1 V, and moreover, a novel non-volatile memory like character emerges in a voltage-sweep measurement. These observations are apparently distinct from those of conventional FETs based on band insulators, capturing the essential feature of collective interactions in strongly correlated materials. This work was done in collaboration with K. Shibuya, D. Okuyama, T. Hatano, S. Ono, M. Kawasaki, Y. Iwasa, and Y. Tokura. This work was supported by the Japan Society for the Promotion of Science (JSAP) through its ``Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program).''

  6. Adaptive semi-supervised recursive tree partitioning: The ART towards large scale patient indexing in personalized healthcare.

    PubMed

    Wang, Fei

    2015-06-01

    With the rapid development of information technologies, tremendous amount of data became readily available in various application domains. This big data era presents challenges to many conventional data analytics research directions including data capture, storage, search, sharing, analysis, and visualization. It is no surprise to see that the success of next-generation healthcare systems heavily relies on the effective utilization of gigantic amounts of medical data. The ability of analyzing big data in modern healthcare systems plays a vital role in the improvement of the quality of care delivery. Specifically, patient similarity evaluation aims at estimating the clinical affinity and diagnostic proximity of patients. As one of the successful data driven techniques adopted in healthcare systems, patient similarity evaluation plays a fundamental role in many healthcare research areas such as prognosis, risk assessment, and comparative effectiveness analysis. However, existing algorithms for patient similarity evaluation are inefficient in handling massive patient data. In this paper, we propose an Adaptive Semi-Supervised Recursive Tree Partitioning (ART) framework for large scale patient indexing such that the patients with similar clinical or diagnostic patterns can be correctly and efficiently retrieved. The framework is designed for semi-supervised settings since it is crucial to leverage experts' supervision knowledge in medical scenario, which are fairly limited compared to the available data. Starting from the proposed ART framework, we will discuss several specific instantiations and validate them on both benchmark and real world healthcare data. Our results show that with the ART framework, the patients can be efficiently and effectively indexed in the sense that (1) similarity patients can be retrieved in a very short time; (2) the retrieval performance can beat the state-of-the art indexing methods. PMID:25656756

  7. Ten-year transient luminous events and Earth observations of FORMOSAT-2

    NASA Astrophysics Data System (ADS)

    Chern, Rock Jeng-Shing; Lin, Shin-Fa; Wu, An-Ming

    2015-07-01

    The purpose of this paper is to summarize the enormous contributions of FS2 (FORMOSAT-2 or Formosa satellite #2) in both Earth and transient luminous events (TLEs) observations in 10 years. As a small satellite operated for 10 years (20 May 2004 to 20 May 2014) in orbit, FS2 keeps its two unique characteristics: (1) to orbit 14 revolutions around the Earth per day with daily revisit capability, and (2) to provide the capabilities of Earth observation in sunlight time and TLEs observation in eclipsed time every day. It carries two payloads: the remote sensing instrument (RSI) for Earth imaging in satellite's day time and the imager of sprites and upper atmospheric lightning instrument (ISUAL) for scientific observations in satellite's night time, respectively. Daily revisit capability provides changes of events on Earth in either short time (several days) or long term (several years). Examples include: Indian Ocean earthquake and tsunami (December 2004), disintegration of Wilkins Ice Shelf in Antarctica region (2006-2014, long term), Sichuan earthquake (May 2008), Tohoku earthquake and tsunami (March 2011), polar regions (2006-2014, long term), etc. In the TLEs observation, ISUAL had recorded more than 35,000 events in 10 years with 73.93% elves, 6.54% red sprites, 5.81% halos, 13.42% blue jets and 0.30% gigantic jets. Major contributions of FS2 in this specific scientific area are presented. In particular, current and future research topics on TLEs are discussed. Also, major contributions of FS2's RSI to the United Nations Institute for Training and Research (UNITAR) Operational Satellite Applications Programme (UNOSAT) and Group of Earth Observation System of Systems (GEOSS) are summarized. This paper also addresses briefly the health status of FS2 after working 10 years in orbit.

  8. Inferences of Diplodocoid (Sauropoda: Dinosauria) Feeding Behavior from Snout Shape and Microwear Analyses

    PubMed Central

    Whitlock, John A.

    2011-01-01

    Background As gigantic herbivores, sauropod dinosaurs were among the most important members of Mesozoic communities. Understanding their ecology is fundamental to developing a complete picture of Jurassic and Cretaceous food webs. One group of sauropods in particular, Diplodocoidea, has long been a source of debate with regard to what and how they ate. Because of their long lineage duration (Late Jurassic-Late Cretaceous) and cosmopolitan distribution, diplodocoids formed important parts of multiple ecosystems. Additionally, fortuitous preservation of a large proportion of cranial elements makes them an ideal clade in which to examine feeding behavior. Methodology/Principal Findings Hypotheses of various browsing behaviors (selective and nonselective browsing at ground-height, mid-height, or in the upper canopy) were examined using snout shape (square vs. round) and dental microwear. The square snouts, large proportion of pits, and fine subparallel scratches in Apatosaurus, Diplodocus, Nigersaurus, and Rebbachisaurus suggest ground-height nonselective browsing; the narrow snouts of Dicraeosaurus, Suuwassea, and Tornieria and the coarse scratches and gouges on the teeth of Dicraeosaurus suggest mid-height selective browsing in those taxa. Comparison with outgroups (Camarasaurus and Brachiosaurus) reinforces the inferences of ground- and mid-height browsing and the existence of both non-selective and selective browsing behaviors in diplodocoids. Conclusions/Significance These results reaffirm previous work suggesting the presence of diverse feeding strategies in sauropods and provide solid evidence for two different feeding behaviors in Diplodocoidea. These feeding behaviors can subsequently be tied to paleoecology, such that non-selective, ground-height behaviors are restricted to open, savanna-type environments. Selective browsing behaviors are known from multiple sauropod clades and were practiced in multiple environments. PMID:21494685

  9. The giant bite of a new raptorial sperm whale from the Miocene epoch of Peru.

    PubMed

    Lambert, Olivier; Bianucci, Giovanni; Post, Klaas; de Muizon, Christian; Salas-Gismondi, Rodolfo; Urbina, Mario; Reumer, Jelle

    2010-07-01

    The modern giant sperm whale Physeter macrocephalus, one of the largest known predators, preys upon cephalopods at great depths. Lacking a functional upper dentition, it relies on suction for catching its prey; in contrast, several smaller Miocene sperm whales (Physeteroidea) have been interpreted as raptorial (versus suction) feeders, analogous to the modern killer whale Orcinus orca. Whereas very large physeteroid teeth have been discovered in various Miocene localities, associated diagnostic cranial remains have not been found so far. Here we report the discovery of a new giant sperm whale from the Middle Miocene of Peru (approximately 12-13 million years ago), Leviathan melvillei, described on the basis of a skull with teeth and mandible. With a 3-m-long head, very large upper and lower teeth (maximum diameter and length of 12 cm and greater than 36 cm, respectively), robust jaws and a temporal fossa considerably larger than in Physeter, this stem physeteroid represents one of the largest raptorial predators and, to our knowledge, the biggest tetrapod bite ever found. The appearance of gigantic raptorial sperm whales in the fossil record coincides with a phase of diversification and size-range increase of the baleen-bearing mysticetes in the Miocene. We propose that Leviathan fed mostly on high-energy content medium-size baleen whales. As a top predator, together with the contemporaneous giant shark Carcharocles megalodon, it probably had a profound impact on the structuring of Miocene marine communities. The development of a vast supracranial basin in Leviathan, extending on the rostrum as in Physeter, might indicate the presence of an enlarged spermaceti organ in the former that is not associated with deep diving or obligatory suction feeding. PMID:20596020

  10. Reproductive Biology and Its Impact on Body Size: Comparative Analysis of Mammalian, Avian and Dinosaurian Reproduction

    PubMed Central

    Werner, Jan; Griebeler, Eva Maria

    2011-01-01

    Janis and Carrano (1992) suggested that large dinosaurs might have faced a lower risk of extinction under ecological changes than similar-sized mammals because large dinosaurs had a higher potential reproductive output than similar-sized mammals (JC hypothesis). First, we tested the assumption underlying the JC hypothesis. We therefore analysed the potential reproductive output (reflected in clutch/litter size and annual offspring number) of extant terrestrial mammals and birds (as “dinosaur analogs”) and of extinct dinosaurs. With the exception of rodents, the differences in the reproductive output of similar-sized birds and mammals proposed by Janis and Carrano (1992) existed even at the level of single orders. Fossil dinosaur clutches were larger than litters of similar-sized mammals, and dinosaur clutch sizes were comparable to those of similar-sized birds. Because the extinction risk of extant species often correlates with a low reproductive output, the latter difference suggests a lower risk of population extinction in dinosaurs than in mammals. Second, we present a very simple, mathematical model that demonstrates the advantage of a high reproductive output underlying the JC hypothesis. It predicts that a species with a high reproductive output that usually faces very high juvenile mortalities will benefit more strongly in terms of population size from reduced juvenile mortalities (e.g., resulting from a stochastic reduction in population size) than a species with a low reproductive output that usually comprises low juvenile mortalities. Based on our results, we suggest that reproductive strategy could have contributed to the evolution of the exceptional gigantism seen in dinosaurs that does not exist in extant terrestrial mammals. Large dinosaurs, e.g., the sauropods, may have easily sustained populations of very large-bodied species over evolutionary time. PMID:22194835

  11. Over the limit.

    PubMed

    Qu, G

    1989-01-01

    With over 1 billion population, China is adding some 15 million to that total each year. And in the 18 years from 1982 to 2000, the net increase of Chinese population is expected to exceed 200 million. Because of the gigantic pressure from population and some mistakes in policies, the levels of ecological destruction and environment pollution are both serious. This includes deforestation, grassland degradation, desert encroachment, water resources shortage, and waste of mineral resources. Natural disasters including floods and droughts caused by those problems happen more and more frequently. If development damages the resource base, it can only result in a false prosperity, the so-called hollow economy. A large number of environmental problems result directly or indirectly from the pressure of population growth. Studies show that the appropriate number of people that can be supported by China's 9.6 million sq. km is about 700 million. However, this limit is now exceeded by over 300 million people, and will be exceeded by 500 million by the end of this century. Therefore, the task is to implement a birth control policy. At present, in urban areas, the goal of family planning has been reached, but in rural areas hard work is needed. Population control in urban areas, especially in big and medium-sized cities, includes dealing with the inflow of migrants from the countryside. There are 13 cities with a population above 2 million, 37 cities above 1-2 million, and 75 cities above 0.5-1 million. A lot of cities are very crowded, exerting great pressure on the environment. The booming of rural enterprises could provide a good solution to control the flow of rural people into big and medium-sized cities. The relationship between population, resources, environment, and development should be managed properly. PMID:12291350

  12. Earthquake calamity warning from space station: orbital dynamics coupling geology mantle convection

    NASA Astrophysics Data System (ADS)

    Szu, Harold H.; Liu, Han-Shou

    2009-04-01

    It is not surprising that the earthquakes happened among clashing tectonic plate boundaries where numerous earthquake stations exist. Then, why do we need more? The significance of Sichuan and Tongshan earthquakes of China is a wakeup call that major earthquakes of logarithmic Richter scales beyond 7 could happen exactly within a single tectonic plate surprisingly. Thus, the previous border surveillance is broadened to areas coverage. Judging the success of archival survey of NASA with the gravitational potential by Liu et al., we review a unified earthquakes theory covering both the peripheral and the central plate in this paper, so that we can take seriously the need of a comprehensive global surveillance of natural calamity in the Space. The earth surface crust, like a kitchen kettle lid, covers tightly the melted mantle rock layer, like a pea soup cooking in the kettle. Given the time they will all become bubbling, rattling & shaking, known as the Bernard instability. This instability is ubiquitous for any liquid state matter being heated from below, if and only if it has a real positive thermal expansion coefficient. Likewise, the earth mantle is being cooked from below by an enormously hot fireball of the size of a moon. The heat comes from the radioactive decay confined within the core over eon's age. Due to the enormous gravitation attraction being always real positive and additive, the inner core is bifurcated into 2 regimes, a heat-melted liquid metal regime, where the earth magnetic field is produced and predicted by Faraday induction law. And further inside there exists a tightly squeezed solid metal ball regime, due to the gigantic weight compression, as confirmed by sonar experiments. The complexity of earth Bernard instability is due to the extra rotational Coriolis force that makes the up-down thermal convection side-way, creating the mass imbalance and permitting in-situ measurements feasible at a distance.

  13. Investigating onychophoran gas exchange and water balance as a means to inform current controversies in arthropod physiology.

    PubMed

    Clusella-Trullas, Susana; Chown, Steven L

    2008-10-01

    Several controversies currently dominate the fields of arthropod metabolic rate, gas exchange and water balance, including the extent to which modulation of gas exchange reduces water loss, the origins of discontinuous gas exchange, the relationship between metabolic rate and life-history strategies, and the causes of Palaeozoic gigantism. In all of these areas, repeated calls have been made for the investigation of groups that might most inform the debates, especially of taxa in key phylogenetic positions. Here we respond to this call by investigating metabolic rate, respiratory water loss and critical oxygen partial pressure (Pc) in the onychophoran Peripatopsis capensis, a member of a group basal to the arthropods, and by synthesizing the available data on the Onychophora. The rate of carbon dioxide release (VCO2) at 20 degrees C in P. capensis is 0.043 ml CO2 h(-1), in keeping with other onychophoran species; suggesting that low metabolic rates in some arthropod groups are derived. Continuous gas exchange suggests that more complex gas exchange patterns are also derived. Total water loss in P. capensis is 57 mg H2O h(-1) at 20 degrees C, similar to modern estimates for another onychophoran species. High relative respiratory water loss rates ( approximately 34%; estimated using a regression technique) suggest that the basal condition in arthropods may be a high respiratory water loss rate. Relatively high Pc values (5-10% O2) suggest that substantial safety margins in insects are also a derived condition. Curling behaviour in P. capensis appears to be a strategy to lower energetic costs when resting, and the concomitant depression of water loss is a proximate consequence of this behaviour. PMID:18805813

  14. Simulação de ejeções de massa coronal

    NASA Astrophysics Data System (ADS)

    Corsini, M. A.; Silva, A. V. R.

    2003-08-01

    Ejeções de massa coronal (EMC) são bolhas gigantes de gás permeadas por campos magnéticos que são ejetadas do Sol durante um período de várias horas. Caso estas ejeções atinjam a Terra, geralmente, causam uma série de distúrbios às comunicações de longa distância e navegação, além de danos a satélites e transformadores. Portanto, é desejável que sejamos capazes de prever quando estas ejeções atingirão a Terra. Para tanto, é necessário um bom entendimento dos mecanismos causadores das ejeções e, principalmente, de como se dá a propagação das EMC e sua interação com o vento solar que permeia o meio interplanetário. Nesse sentido foi desenvolvido um programa computacional para resolver as equações MHD (Magneto-Hidro-Dinâmica) que regem a evolução das EMC. Primeiramente foram estabelecidas as condições necessárias para descrever o vento solar, no estado estacionário, que permeia todo o meio interplanetário. Num primeiro momento, resolveu-se o sistema de equações para o caso do vento isotérmico, conhecida como a solução de Parker, a fim de testarmos o modelo. Então, foi considerado o caso do vento solar com temperatura variável no meio interplanetário. Este resultado foi utilizado como a base de nosso sistema em seu instante inicial. Posteriormente foram feitas as considerações necessárias para descrever a propagação da Ejeção de Massa Coronal. As EMC foram simuladas como um aumento de densidade e temperatura local na coroa solar. A órbita e a posição da Terra foram incluídas no sistema. Os dados gerados possibilitaram uma análise da evolução da EMC pelo meio interplanetário até encontrar-se com a Terra. Os perfis de densidade e temperatura a 1 Unidade Astronômica são comparados com os dados de satélites reportados na literatura.

  15. A New Sauropodomorph Dinosaur from the Early Jurassic of Patagonia and the Origin and Evolution of the Sauropod-type Sacrum

    PubMed Central

    Pol, Diego; Garrido, Alberto; Cerda, Ignacio A.

    2011-01-01

    Background The origin of sauropod dinosaurs is one of the major landmarks of dinosaur evolution but is still poorly understood. This drastic transformation involved major skeletal modifications, including a shift from the small and gracile condition of primitive sauropodomorphs to the gigantic and quadrupedal condition of sauropods. Recent findings in the Late Triassic–Early Jurassic of Gondwana provide critical evidence to understand the origin and early evolution of sauropods. Methodology/Principal Findings A new sauropodomorph dinosaur, Leonerasaurus taquetrensis gen. et sp. nov., is described from the Las Leoneras Formation of Central Patagonia (Argentina). The new taxon is diagnosed by the presence of anterior unserrated teeth with a low spoon-shaped crown, amphicoelous and acamerate vertebral centra, four sacral vertebrae, and humeral deltopectoral crest low and medially deflected along its distal half. The phylogenetic analysis depicts Leonerasaurus as one of the closest outgroups of Sauropoda, being the sister taxon of a clade of large bodied taxa composed of Melanorosaurus and Sauropoda. Conclusions/Significance The dental and postcranial anatomy of Leonerasaurus supports its close affinities with basal sauropods. Despite the small size and plesiomorphic skeletal anatomy of Leonerasaurus, the four vertebrae that compose its sacrum resemble that of the large-bodied primitive sauropods. This shows that the appearance of the sauropod-type of sacrum predated the marked increase in body size that characterizes the origins of sauropods, rejecting a causal explanation and evolutionary linkage between this sacral configuration and body size. Alternative phylogenetic placements of Leonerasaurus as a basal anchisaurian imply a convergent acquisition of the sauropod-type sacrum in the new small-bodied taxon, also rejecting an evolutionary dependence of sacral configuration and body size in sauropodomorphs. This and other recent discoveries are showing that the characteristic sauropod body plan evolved gradually, with a step-wise pattern of character appearance. PMID:21298087

  16. The evolution of high energy accelerators

    SciTech Connect

    Courant, E.D.

    1994-08-01

    Accelerators have been devised and built for two reasons: In the first place, by physicists who needed high energy particles in order to have a means to explore the interactions between particles that probe the fundamental elementary forces of nature. And conversely, sometimes accelerator builders produce new machines for higher energy than ever before just because it can be done, and then challenge potential users to make new discoveries with the new means at hand. These two approaches or motivations have gone hand in hand. This lecture traces how high energy particle accelerators have grown from tools used for esoteric small-scale experiments to the gigantic projects of today. So far all the really high-energy machines built and planned in the world--except the SLC--have been ring accelerators and storage rings using the strong-focusing method. But this method has not removed the energy limit, it has only pushed it higher. It would seem unlikely that one can go beyond the Large Hadron Collider (LHC)--but in fact a workshop was held in Sicily in November 1991, concerned with the question of extrapolating to 100 TeV. Other acceleration and beam-forming methods are now being discussed--collective fields, laser acceleration, wake-field accelerators etc., all aimed primarily at making linear colliders possible and more attractive than with present radiofrequency methods. So far it is not entirely clear which of these schemes will dominate particle physics in the future--maybe something that has not been thought of as yet.

  17. Gravity for Detecting Caves: Airborne and Terrestrial Simulations Based on a Comprehensive Karstic Cave Benchmark

    NASA Astrophysics Data System (ADS)

    Braitenberg, Carla; Sampietro, Daniele; Pivetta, Tommaso; Zuliani, David; Barbagallo, Alfio; Fabris, Paolo; Rossi, Lorenzo; Fabbri, Julius; Mansi, Ahmed Hamdi

    2015-10-01

    Underground caves bear a natural hazard due to their possible evolution into a sink hole. Mapping of all existing caves could be useful for general civil usages as natural deposits or tourism and sports. Natural caves exist globally and are typical in karst areas. We investigate the resolution power of modern gravity campaigns to systematically detect all void caves of a minimum size in a given area. Both aerogravity and terrestrial acquisitions are considered. Positioning of the gravity station is fastest with GNSS methods the performance of which is investigated. The estimates are based on a benchmark cave of which the geometry is known precisely through a laser-scan survey. The cave is the Grotta Gigante cave in NE Italy in the classic karst. The gravity acquisition is discussed, where heights have been acquired with dual-frequency geodetic GNSS receivers and Total Station. Height acquisitions with non-geodetic low-cost receivers are shown to be useful, although the error on the gravity field is larger. The cave produces a signal of -1.5 × 10-5 m/s2, with a clear elliptic geometry. We analyze feasibility of airborne gravity acquisitions for the purpose of systematically mapping void caves. It is found that observations from fixed wing aircraft cannot resolve the caves, but observations from slower and low-flying helicopters or drones do. In order to detect the presence of caves the size of the benchmark cave, systematic terrestrial acquisitions require a density of three stations on square 500 by 500 m2 tiles. The question has a large impact on civil and environmental purposes, since it will allow planning of urban development at a safe distance from subsurface caves. The survey shows that a systematic coverage of the karst would have the benefit to recover the position of all of the greater existing void caves.

  18. Change in and long-term investigation of neuro-otologic disorders in disaster-stricken Fukushima prefecture: retrospective cohort study before and after the Great East Japan Earthquake.

    PubMed

    Hasegawa, Jun; Hidaka, Hiroshi; Kuriyama, Shinichi; Obara, Taku; Hashimoto, Ken; Tateda, Yutaka; Okumura, Yuri; Kobayashi, Toshimitsu; Katori, Yukio

    2015-01-01

    On March 11, 2011, Japan's northeast Pacific coast was hit by a gigantic earthquake and subsequent tsunami. Soma City in Fukushima Prefecture is situated approximately 44 km north of Fukushima Daiichi Nuclear Power Plant. Soma General Hospital is the only hospital in Soma City that provides full-time otolaryngological medical care. We investigated the changes in new patients from one year before to three years after the disaster. We investigated 18,167 new patients treated at our department during the four years from April 1, 2010 to March 31, 2014. Of the new patients, we categorized the diagnoses into Meniere's disease, acute low-tone sensorineural hearing loss, vertigo, sudden deafness, tinnitus, and facial palsy as neuro-otologic symptoms. We also investigated the changes in the numbers of patients whom we examined at that time concerning other otolaryngological disorders, including epistaxis, infectious diseases of the laryngopharynx, and allergic rhinitis. The total number of new patients did not change remarkably on a year-to-year basis. Conversely, cases of vertigo, Meniere's disease, and acute low-tone sensorineural hearing loss increased in number immediately after the disaster, reaching a plateau in the second year and slightly decreasing in the third year. Specifically, 4.8% of patients suffering from these neuro-otologic diseases had complications from depression and other mental diseases. With regard to new patients in our department, there was no apparent increase in the number of patients suffering from diseases other than neuro-otologic diseases, including epistaxis, and allergic rhinitis. Patients suffering from vertigo and/or dizziness increased during the first few years after the disaster. These results are attributed to the continuing stress and tension of the inhabitants. This investigation of those living in the disaster area highlights the need for long-term support. PMID:25849607

  19. Visions of our Planet's Atmosphere, Land and Oceans: NASA/NOAA Electronic Theater 2002

    NASA Technical Reports Server (NTRS)

    Haser, Fritz; Starr, David (Technical Monitor)

    2002-01-01

    The NASA/NOAA Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to the 2002 Winter Olympic Stadium Site of the Olympic Opening and Closing Ceremonies in Salt Lake City. Fly in and through Olympic Alpine Venues using 1 m IKONOS "Spy Satellite" data. Go back to the early weather satellite images from the 1960s and see them contrasted with the latest US and international global satellite weather movies including hurricanes and "tornadoes". See the latest visualizations of spectacular images from NASA/NOAA remote sensing missions like Terra, GOES, TRMM, SeaWiFS, Landsat 7 including new 1 - min GOES rapid scan image sequences of Nov 9th 2001 Midwest tornadic thunderstorms and have them explained. See how High-Definition Television (HDTV) is revolutionizing the way we communicate science. (In cooperation with the American Museum of Natural History in NYC) See dust storms in Africa and smoke plumes from fires in Mexico. See visualizations featured on the covers of Newsweek, TIME, National Geographic, Popular Science and on National and International Network TV. New computer software tools allow us to roam and zoom through massive global images e.g. Landsat tours of the US, and Africa, showing desert and mountain geology as well as seasonal changes in vegetation. See animations of the polar ice packs and the motion of gigantic Antarctic Icebergs from SeaWinds. data. Spectacular new visualizations of the global atmosphere and oceans are shown. See vortexes and currents in the global oceans that bring up the nutrients to feed tiny algae and draw the fish, whales and fisherman. See the how the ocean blooms in response to these currents and El Nino/La Nina climate changes. See the city lights, fishing fleets, gas flares and bio-mass burning of the Earth at night observed by the "night-vision" DMSP military satellite.

  20. Visions of our Planet's Atmosphere, Land and Oceans: NASA/NOAA Electronic-Theater 2002. Spectacular Visualizations of our Blue Marble

    NASA Technical Reports Server (NTRS)

    Hasler, A. F.; Starr, David (Technical Monitor)

    2002-01-01

    Spectacular Visualizations of our Blue Marble The NASA/NOAA Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to the 2002 Winter Olympic Stadium Site of the Olympic Opening and Closing Ceremonies in Salt Lake City. Fly in and through Olympic Alpine Venues using 1 m IKONOS "Spy Satellite" data. Go back to the early weather satellite images from the 1960s and see them contrasted with the latest US and international global satellite weather movies including hurricanes & "tornadoes". See the latest visualizations of spectacular images from NASA/NOAA remote sensing missions like Terra, GOES, TRMM, SeaWiFS, Landsat 7 including new 1 - min GOES rapid scan image sequences of Nov 9th 2001 Midwest tornadic thunderstorms and have them explained. See how High-Definition Television (HDTV) is revolutionizing the way we communicate science. (In cooperation with the American Museum of Natural History in NYC). See dust storms in Africa and smoke plumes from fires in Mexico. See visualizations featured on the covers of Newsweek, TIME, National Geographic, Popular Science & on National & International Network TV. New computer software tools allow us to roam & zoom through massive global images e.g. Landsat tours of the US, and Africa, showing desert and mountain geology as well as seasonal changes in vegetation. See animations of the polar ice packs and the motion of gigantic Antarctic Icebergs from SeaWinds data. Spectacular new visualizations of the global atmosphere & oceans are shown. See vertexes and currents in the global oceans that bring up the nutrients to feed tiny algae and draw the fish, whales and fisherman. See the how the ocean blooms in response to these currents and El Nicola Nina climate changes. See the city lights, fishing fleets, gas flares and biomass burning of the Earth at night observed by the "night-vision" DMSP military satellite.

  1. Visions of Our Planet's Atmosphere, Land and Oceans Electronic-Theater 2001

    NASA Technical Reports Server (NTRS)

    Hasler, A. F.; Einaudi, Franco (Technical Monitor)

    2001-01-01

    The NASA/NOAA/AMS Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to Fredericton New Brunswick. Drop in on the Kennedy Space Center and Park City Utah, site of the 2002 Olympics using 1 m IKONOS "Spy Satellite" data. Go back to the early weather satellite images from the 1960s and see them contrasted with the latest US and International global satellite weather movies including hurricanes & tornadoes. See the latest spectacular images from NASA/NOAA and Canadian remote sensing missions like Terra GOES, TRMM, SeaWiFS, Landsat 7, and Radarsat that are visualized & explained. See how High Definition Television (HDTV) is revolutionizing the way we communicate science in cooperation with the American Museum of Natural History in NYC. See dust storms in Africa and smoke plumes from fires in Mexico. See visualizations featured on Newsweek, TIME, National Geographic, Popular Science covers & National & International Network TV. New visualization tools allow us to roam & zoom through massive global images eg Landsat tours of the US, Africa, & New Zealand showing desert and mountain geology as well as seasonal changes in vegetation. See animations of the polar ice packs and the motion of gigantic Antarctic Icebergs from SeaWinds data. Spectacular new visualizations of the global atmosphere & oceans are shown. See massive dust storms sweeping across Africa. See vortexes and currents in the global oceans that bring up the nutrients to feed tiny plankton and draw the fish, whales and fisherman. See the how the ocean blooms in response to these currents and El Nino/La Nina climate changes. The demonstration is interactively driven by a SGI Onyx II Graphics Supercomputer with four CPUs, 8 Gigabytes of RAM and Terabyte of disk. With multiple projectors on a giant screen. See the city lights, fishing fleets, gas flares and bio-mass burning of the Earth at night observed by the "night-vision" DMSP military satellite.

  2. Change in and Long-Term Investigation of Neuro-Otologic Disorders in Disaster-Stricken Fukushima Prefecture: Retrospective Cohort Study before and after the Great East Japan Earthquake

    PubMed Central

    Kuriyama, Shinichi; Obara, Taku; Hashimoto, Ken; Tateda, Yutaka; Okumura, Yuri; Kobayashi, Toshimitsu; Katori, Yukio

    2015-01-01

    On March 11, 2011, Japan’s northeast Pacific coast was hit by a gigantic earthquake and subsequent tsunami. Soma City in Fukushima Prefecture is situated approximately 44 km north of Fukushima Daiichi Nuclear Power Plant. Soma General Hospital is the only hospital in Soma City that provides full-time otolaryngological medical care. We investigated the changes in new patients from one year before to three years after the disaster. We investigated 18,167 new patients treated at our department during the four years from April 1, 2010 to March 31, 2014. Of the new patients, we categorized the diagnoses into Meniere’s disease, acute low-tone sensorineural hearing loss, vertigo, sudden deafness, tinnitus, and facial palsy as neuro-otologic symptoms. We also investigated the changes in the numbers of patients whom we examined at that time concerning other otolaryngological disorders, including epistaxis, infectious diseases of the laryngopharynx, and allergic rhinitis. The total number of new patients did not change remarkably on a year-to-year basis. Conversely, cases of vertigo, Meniere’s disease, and acute low-tone sensorineural hearing loss increased in number immediately after the disaster, reaching a plateau in the second year and slightly decreasing in the third year. Specifically, 4.8% of patients suffering from these neuro-otologic diseases had complications from depression and other mental diseases. With regard to new patients in our department, there was no apparent increase in the number of patients suffering from diseases other than neuro-otologic diseases, including epistaxis, and allergic rhinitis. Patients suffering from vertigo and/or dizziness increased during the first few years after the disaster. These results are attributed to the continuing stress and tension of the inhabitants. This investigation of those living in the disaster area highlights the need for long-term support. PMID:25849607

  3. Mechanical Analysis of Feeding Behavior in the Extinct “Terror Bird” Andalgalornis steulleti (Gruiformes: Phorusrhacidae)

    PubMed Central

    Degrange, Federico J.; Tambussi, Claudia P.; Moreno, Karen; Witmer, Lawrence M.; Wroe, Stephen

    2010-01-01

    The South American phorusrhacid bird radiation comprised at least 18 species of small to gigantic terrestrial predators for which there are no close modern analogs. Here we perform functional analyses of the skull of the medium-sized (?40 kg) patagornithine phorusrhacid Andalgalornis steulleti (upper Miocene–lower Pliocene, Andalgalá Formation, Catamarca, Argentina) to assess its mechanical performance in a comparative context. Based on computed tomographic (CT) scanning and morphological analysis, the skull of Andalgalornis steulleti is interpreted as showing features reflecting loss of intracranial immobility. Discrete anatomical attributes permitting such cranial kinesis are widespread phorusrhacids outgroups, but this is the first clear evidence of loss of cranial kinesis in a gruiform bird and may be among the best documented cases among all birds. This apomorphic loss is interpreted as an adaptation for enhanced craniofacial rigidity, particularly with regard to sagittal loading. We apply a Finite Element approach to a three-dimensional (3D) model of the skull. Based on regression analysis we estimate the bite force of Andalgalornis at the bill tip to be 133 N. Relative to results obtained from Finite Element Analysis of one of its closest living relatives (seriema) and a large predatory bird (eagle), the phorusrhacid's skull shows relatively high stress under lateral loadings, but low stress where force is applied dorsoventrally (sagittally) and in “pullback” simulations. Given the relative weakness of the skull mediolaterally, it seems unlikely that Andalgalornis engaged in potentially risky behaviors that involved subduing large, struggling prey with its beak. We suggest that it either consumed smaller prey that could be killed and consumed more safely (e.g., swallowed whole) or that it used multiple well-targeted sagittal strikes with the beak in a repetitive attack-and-retreat strategy. PMID:20805872

  4. The Liang Bua faunal remains: a 95k.yr. sequence from Flores, East Indonesia.

    PubMed

    van den Bergh, G D; Meijer, H J M; Due Awe, Rokhus; Morwood, M J; Szabó, K; van den Hoek Ostende, L W; Sutikna, T; Saptomo, E W; Piper, P J; Dobney, K M

    2009-11-01

    Excavations at Liang Bua, a limestone cave on the island of Flores, East Indonesia, have yielded a well-dated archaeological and faunal sequence spanning the last 95k.yr., major climatic fluctuations, and two human species -H. floresiensis from 95 to 17k.yr.(1), and modern humans from 11k.yr. to the present. The faunal assemblage comprises well-preserved mammal, bird, reptile and mollusc remains, including examples of island gigantism in small mammals and the dwarfing of large taxa. Together with evidence from Early-Middle Pleistocene sites in the Soa Basin, it confirms the long-term isolation, impoverishment, and phylogenetic continuity of the Flores faunal community. The accumulation of Stegodon and Komodo dragon remains at the site in the Pleistocene is attributed to Homo floresiensis, while predatory birds, including an extinct species of owl, were largely responsible for the accumulation of the small vertebrates. The disappearance from the sequence of the two large-bodied, endemic mammals, Stegodon florensis insularis and Homo floresiensis, was associated with a volcanic eruption at 17 ka and precedes the earliest evidence for modern humans, who initiated use of mollusc and shell working, and began to introduce a range of exotic animals to the island. Faunal introductions during the Holocene included the Sulawesi warty pig (Sus celebensis) at about 7ka, followed by the Eurasian pig (Sus scrofa), Long-tailed macaque, Javanese porcupine, and Masked palm civet at about 4ka, and cattle, deer, and horse - possibly by the Portuguese within historic times. The Holocene sequence at the site also documents local faunal extinctions - a result of accelerating human population growth, habitat loss, and over-exploitation. PMID:19058833

  5. The 1963 Vajont landslide (Italy) simulated through a numerical 2D code

    NASA Astrophysics Data System (ADS)

    Zaniboni, Filippo; Ausilia Paparo, Maria; Elsen, Katharina; Tinti, Stefano

    2013-04-01

    On October 9th, 1963, a huge mass of about 260 million m3 collapsed along Mt. Toc flank into the artificial lake called Vajont and generated a gigantic wave that invested the town of Longarone (North-East Italy, about 100 km north of Venice), provoking about 2000 casualties. The event started a public debate on the responsibilities for the disaster, and also raised crucial issues for the scientific and engineering community, regarding reservoir flank instability and safety of the hydroelectric plant. The peculiar features of the event were immediately evident. The clay layers remained uncovered in the upper part of the detachment niche, supporting the hypothesis of a well-defined pre-existing sliding surface, that could explain the high falling velocity (around 20 m/s as a maximum) and the compactness of the deposit layers that were found to sit almost unperturbed on the bottom of the valley. The numerical study presented here contributes to the understanding of dynamics of the Vajont landslide. It is found that the accurate knowledge of the pre- and post-slide morphology provides tight constraints on the parameters of the numerical model, that are tuned to fit the observed deposit. Numerical simulations are carried out by means of the in-house built code UBO-BLOCK2. The initial sliding body is divided into a mesh of interacting volume-conserving blocks, whose motion is computed numerically. The friction coefficient at the base of the landslide is determined through a best fit search by maximizing the degree of overlapping between the calculated and observed deposits. Our best solution is also able to account for the observed slight easterly rotation of the mass, the different behaviors of the eastern and western part of the sliding surface and the retrogressive motion of the slide that after climbing up the opposite flank of the valley reverted velocity to settle down on the bottom of the valley.

  6. The 1994 EUROMET collection of micrometeorites at Cap-Prudhomme, Antarctica

    NASA Astrophysics Data System (ADS)

    Maurette, M.; Immel, G.; Engrand, C.; Kurat, G.; Pillinger, C. T.

    1994-07-01

    Advance funding from IFRTP (Institut Francais pour la Recherche et pour la Technique Polaire) for micrometeorite collection at Cap-Prudhomme has allowed construction of a new micrometeorite 'factory,' conceived to greatly reduce contamination of the ultraclean ice by our activities. The potential problems include fly ash, rust grains, fuel spills 'sticking to the shoes,' and trace elements from the plasticizers used in plastic tubing. In the new factory, intended to produce and then cycle 10-15 tons of melt ice water per day, all parts exposed to water were replaced by either stainless steel or teflon. After examination with a microscope and their transfer into teflon and or glass vials, all samples were frozen the day of their collection. The factory operated from December 15, 1993, through February 6, 1994. Problems included injuries as well as very bad weather conditions, characterized by both the heaviest snow falls observed and unexpected gusts from a blizzard. Also, several new components of the factory did not function properly under the extreme conditions of Antarctica. Our major objective was to obtain the 'cleanest' and 'purest' 25-50 microns micrometeorites ever collected in Antarctica, for comparison with stratospheric Interplanetary Dust Particles (IDPs). We could not fulfill this premise, but we recovered the best 100-400-micron-size fraction of 'giant' micrometeorites ever collected on Earth. Our 26 daily collections are listed,refering to an 'index of quality.' Aliquots of these daily collections will be distributed to major institutions in Austria, England, the U.S.A., and Japan, to be preserved for future generations. The Antarctica ice sheet is truly a gigantic, ultraclean, and inexhaustible micrometeorite collector, but it is very tricky to recover 'ultraclean' micrometeorites from it.

  7. Twisting Tourniquet© Technique: introducing Schnogh, a novel device and its effectiveness in treating primary and secondary lymphedema of extremities

    PubMed Central

    Chanwimalueang, Narumon; Ekataksin, Wichai; Piyaman, Parkpoom; Pattanapen, Gedsuda; Hanboon, Borimas K

    2015-01-01

    Twisting Tourniquet© or in Thai “Schnogh” is a new invention for compression therapy of lymphedema. Twisting Tourniquet© Technique (TTT) is totally noninvasive for lymphedema management. After the amazing successful evidence in the first series of 28 patients, we have conducted preliminary studies in lymphedema clinics. It was found that the combination of gradually increasing constriction force by Schnogh until desired pressure was reached and maintained for 15 min, followed by a 5-min release, doing repeatedly this compression-decompression for at least 10 sessions a day, can generate acceptable results. The aim of the study was to evaluate the scientific effectiveness and establish a treatment protocol of TTT proposed as a therapeutic approach for clinical management of lymphedema. During 2006–2013, from over 3500 patients, 647 with primary/secondary lymphedema passed inclusion criteria, 307 for upper, and 340 for lower extremity. In the 5-day course of TTT, each day patients underwent 10 sessions of a 15-min compression followed by a 5-min decompression. Vegan diet was encouraged as an adjuvant therapy. Among lymphedema patients whose spectrum of edema severity ranged from mild to gigantic, TTT yielded an average volume reduction rate (VR) at 50.2% and 55.6%, making the average edema reduction volume attained at 463 and 1856 mL for upper and lower limb, respectively. The uniformed practice by Schnogh which supports a continual compression–decompression maneuver over 3.5 h daily for five consecutive days could induce an average VR at above half of the swelling in extremities of 647 patients. Schnogh is therefore effective in clinical management of lymphedema under TTT treatment of fibroblastic interstitium. PMID:26247407

  8. Cometary Knots Around A Dying Star

    NASA Technical Reports Server (NTRS)

    1994-01-01

    These gigantic, tadpole-shaped objects are probably the result of a dying star's last gasps. Dubbed 'cometary knots' because their glowing heads and gossamer tails resemble comets, the gaseous objects probably were formed during a star's final stages of life. Hubble astronomer C. Robert O'Dell and graduate student Kerry P. Handron of Rice University in Houston, Texas discovered thousands of these knots with the Hubble Space Telescope while exploring the Helix nebula, the closest planetary nebula to Earth at 450 light-years away in the constellation Aquarius. Although ground-based telescopes have revealed such objects, astronomers have never seen so many of them. The most visible knots all lie along the inner edge of the doomed star's ring, trillions of miles away from the star's nucleus. Although these gaseous knots appear small, they're actually huge. Each gaseous head is at least twice the size of our solar system; each tail stretches for 100 billion miles, about 1,000 times the distance between the Earth and the Sun. Astronomers theorize that the doomed star spews hot, lower-density gas from its surface, which collides with cooler, higher-density gas that had been ejected 10,000 years before. The crash fragments the smooth cloud surrounding the star into smaller, denser finger-like droplets, like dripping paint. This image was taken in August, 1994 with Hubble's Wide Field Planetary Camera 2. The red light depicts nitrogen emission ([NII] 6584A); green, hydrogen (H-alpha, 6563A); and blue, oxygen (5007A).

  9. First Direct Dating for the Construction and Modification of the Baphuon Temple Mountain in Angkor, Cambodia.

    PubMed

    Leroy, Stéphanie; Hendrickson, Mitch; Delqué-Kolic, Emmanuelle; Vega, Enrique; Dillmann, Philippe

    2015-01-01

    Architecture represents key evidence of dynastic practice and change in the archaeological world. Chronologies for many important buildings and sequences, including the iconic temples of medieval Angkor in Cambodia, are based solely on indirect associations from inscriptions and architectural styles. The Baphuon temple, one of the last major buildings in Angkor without textual or scientifically-derived chronological evidence, is crucial both for the context and date of its construction and the period when its western façade was modified into a unique, gigantic Reclining Buddha. Its construction was part of a major dynastic change and florescence of the Hindu-Mahayana Buddhist state and the modification is the key evidence of Theravada Buddhist power after Angkor's decline in the 15th century. Using a newly-developed approach based on AMS radiocarbon dating to directly date four iron crampons integrated into the structure we present the first direct evidence for the history of the Baphuon. Comprehensive study of ferrous elements shows that both construction and modification were critically earlier than expected. The Baphuon can now be considered as the major temple associated with the imperial reformations and territorial consolidation of Suryavarman I (1010-1050 AD) for whom no previous building to legitimize his reign could be identified. The Theravada Buddhist modification is a hundred years prior to the conventional 16th century estimation and is not associated with renewed use of Angkor. Instead it relates to the enigmatic Ayutthayan occupation of Angkor in the 1430s and 40s during a major period of climatic instability. Accurately dating iron with relatively low carbon content is a decisive step to test long-standing assumptions about architectural histories and political processes for states that incorporated iron into buildings (e.g., Ancient Greece, medieval India). Furthermore, this new approach has the potential to revise chronologies related to iron consumption practices since the origins of ferrous metallurgy three millennia ago. PMID:26535895

  10. Muzzle of South American Pleistocene ground sloths (Xenarthra, Tardigrada).

    PubMed

    Bargo, M Susana; Toledo, Néstor; Vizcaíno, Sergio F

    2006-02-01

    Sloths are among the most characteristic elements of the Cainozoic of South America and are represented, during the Pleistocene, by approximately nine genera of gigantic ground sloths (Megatheriidae and Mylodontidae). A few contributions have described their masticatory apparatus, but almost no attention has been paid to the reconstruction of the muzzle, an important feature to consider in relation to food intake, and particularly relevant in sloths because of the edentulous nature of the muzzle and its varied morphology. The relationship between dietary habits and shape and width of the muzzle is well documented in living herbivores and has been considered an important feature for the inference of alimentary styles in fossils, providing an interesting methodological tool that deserves to be considered for xenarthrans. The goal of this study was to examine models of food intake by reconstructing the appearance and shape of the muzzle in five species of Pleistocene ground sloths (Megatherium americanum, Glossotherium robustum, Lestodon armatus, Mylodon darwini, and Scelidotherium leptocephalum) using reconstructions of the nasal cartilages and facial muscles involved in food intake. The preservation of the nasal septum, and the scars for muscular attachment in the rostral part of the skulls, allow making a conservative reconstruction of muzzle anatomy in fossil sloths. Wide-muzzled ground sloths (Glossotherium and Lestodon) had a square, nonprehensile upper lip and were mostly bulk-feeders. The lips, coupled with the tongue, were used to pull out grass and herbaceous plants. Narrow-muzzled sloths (Mylodon, Scelidotherium, and Megatherium) had a cone-shaped and prehensile lip and were mixed or selective feeders. The prehensile lip was used to select particular plants or plant parts. PMID:16315216

  11. Testing for intraspecific postzygotic isolation between cryptic lineages of Pseudacris crucifer

    PubMed Central

    Stewart, Kathryn A; Lougheed, Stephen C

    2013-01-01

    Phenotypically cryptic lineages appear common in nature, yet little is known about the mechanisms that initiate and/or maintain barriers to gene flow, or how secondary contact between them might influence evolutionary trajectories. The consequences of such contact between diverging lineages depend on hybrid fitness, highlighting the potential for postzygotic isolating barriers to play a role in the origins of biological species. Previous research shows that two cryptic, deeply diverged intraspecific mitochondrial lineages of a North American chorus frog, the spring peeper (Pseudacris crucifer), meet in secondary contact in Southwestern Ontario, Canada. Our study quantified hatching success, tadpole survival, size at metamorphosis, and development time for experimentally generated pure lineage and hybrid tadpoles. Results suggest that lineages differ in tadpole survival and that F1 hybrids may have equal fitness and higher than average mass at metamorphosis compared with pure parental crosses. These findings imply hybrid early life viability may not be the pivotal reproductive isolation barrier helping to maintain lineage boundaries. However, we observed instances of tadpole gigantism, failure to metamorphose, and bent tails in some tadpoles from hybrid families. We also speculate and provide some evidence that apparent advantages or similarities of hybrids compared with pure lineage tadpoles may disappear when tadpoles are raised with competitors of different genetic makeup. This pilot study implies that ecological context and consideration of extrinsic factors may be a key to revealing mechanisms causing negative hybrid fitness during early life stages, a provocative avenue for future investigations on barriers to gene flow among these intraspecific lineages. PMID:24363891

  12. First Direct Dating for the Construction and Modification of the Baphuon Temple Mountain in Angkor, Cambodia

    PubMed Central

    Leroy, Stéphanie; Hendrickson, Mitch; Delqué-Kolic, Emmanuelle; Vega, Enrique; Dillmann, Philippe

    2015-01-01

    Architecture represents key evidence of dynastic practice and change in the archaeological world. Chronologies for many important buildings and sequences, including the iconic temples of medieval Angkor in Cambodia, are based solely on indirect associations from inscriptions and architectural styles. The Baphuon temple, one of the last major buildings in Angkor without textual or scientifically-derived chronological evidence, is crucial both for the context and date of its construction and the period when its western façade was modified into a unique, gigantic Reclining Buddha. Its construction was part of a major dynastic change and florescence of the Hindu-Mahayana Buddhist state and the modification is the key evidence of Theravada Buddhist power after Angkor's decline in the 15th century. Using a newly-developed approach based on AMS radiocarbon dating to directly date four iron crampons integrated into the structure we present the first direct evidence for the history of the Baphuon. Comprehensive study of ferrous elements shows that both construction and modification were critically earlier than expected. The Baphuon can now be considered as the major temple associated with the imperial reformations and territorial consolidation of Suryavarman I (1010–1050 AD) for whom no previous building to legitimize his reign could be identified. The Theravada Buddhist modification is a hundred years prior to the conventional 16th century estimation and is not associated with renewed use of Angkor. Instead it relates to the enigmatic Ayutthayan occupation of Angkor in the 1430s and 40s during a major period of climatic instability. Accurately dating iron with relatively low carbon content is a decisive step to test long-standing assumptions about architectural histories and political processes for states that incorporated iron into buildings (e.g., Ancient Greece, medieval India). Furthermore, this new approach has the potential to revise chronologies related to iron consumption practices since the origins of ferrous metallurgy three millennia ago. PMID:26535895

  13. West-Antarctic Ice Streams: Analog to Ice Flow in Channels on Mars

    NASA Technical Reports Server (NTRS)

    Lucchitta, B. K.

    1997-01-01

    Sounding of the sea floor in front of the Ross Ice Shelf in Antarctica recently revealed large persistent patterns of longitudinal megaflutes and drumlinoid forms, which are interpreted to have formed at the base of ice streams during the list glacial advance. The flutes bear remarkable resemblance to longitudinal grooves and highly elongated streamlined islands found on the floors of some large martian channels, called outflow channels. ln addition, other similarities exist between Antarctic ice streams and outflow channels. Ice streams are 30 to 80 km wide and hundreds of kilometers long, as are the martian channels. Ice stream beds are below sea level. Floors of many martian outflow channels lie below martian datum, which may have been close to or below past martian sea levels. The Antarctic ice stream bed gradient is flat and locally may go uphill, and surface slopes are exceptionally low. So are gradients of martian channels. The depth to the bed in ice streams is 1 to 1.5 km. At bankful stage, the depth of the fluid in outflow channels would have been 1 to 2 km. These similarities suggest that the martian outflow channels, whose origin is commonly attributed to gigantic catastrophic floods, were locally filled by ice that left a conspicuous morphologic imprint. Unlike the West-Antarctic-ice streams, which discharge ice from an ice sheet, ice in the martian channels came from water erupting from the ground. In the cold martian environment, this water, if of moderate volume, would eventually freeze. Thus it may have formed icings on springs, ice dams and jams on constrictions in the channel path, or frozen pools. Given sufficient thickness and downhill surface gradient, these ice masses would have moved; and given the right conditions, they could have moved like Antarctic ice streams.

  14. August 2014 Hiroshima landslide disaster and its societal impact

    NASA Astrophysics Data System (ADS)

    Fukuoka, Hiroshi; Sassa, Kyoji; Wang, Chunxiang

    2015-04-01

    In the early morning of August 20, 2014, Hiroshima city was hit by a number of debris flows along a linear rain band which caused extreme downpour. This disaster claimed 74 death, although this city experienced very similar disaster in 1999, claiming more than 30 residents lives. In the most severely affected debris flow torrent, more than 50 residents were killed. Most of the casualties arose in the wooden, vulnerable houses constructed in front of the exit of torrents. Points and lessons learnt from the disaster are as follows: 1. Extreme rainfall events : geology and geomorphology does not much affect the distribution of landslides initiation sites. 2. Area of causative extreme rainfall is localized in 2 km x 10 km along the rain band. 3. Authors collected two types of sands from the source scar of the initial debris slides which induced debris flows. Tested by the ring shear apparatus under pore-pressure control condition, clear "Sliding surface liquefaction" was confirmed for both samples even under small normal stress, representing the small thickness of the slides. These results shows even instant excess pore pressure could initiate the slides and trigger slide-induced debris flow by undrained loading onto the torrent deposits. 4. Apparently long-term land-use change affected the vulnerability of the community. Residential area had expanded into hill-slope (mountainous / semi-mountainous area) especially along the torrents. Those communities were developed on the past debris flow fan. 5. As the devastated area is very close to downtown of Hiroshima city, it gave gigantic societal impact to the Japanese citizens. After 1999 Hiroshima debris flow disaster, the Landslide disaster reduction law which intends to promote designation of landslide potential risk zones, was adopted in 2000. Immediately after 2014 disaster, national diet approved revision of the bill.

  15. Building Baluchitherium and Indricotherium: imperial and international networks in early-twentieth century paleontology.

    PubMed

    Manias, Chris

    2015-01-01

    Over the first decades of the twentieth century, the fragmentary remains of a huge prehistoric ungulate were unearthed in scientific expeditions in India, Turkestan and Mongolia. Following channels of formal and informal empire, these were transported to collections in Britain, Russia and the United States. While striking and of immense size, the bones proved extremely difficult to interpret. Alternately naming the creature Paraceratherium, Baluchitherium and Indricotherium, paleontologists Clive Forster-Cooper, Alexei Borissiak and Henry Fairfield Osborn struggled over the reconstruction of this gigantic fossil mammal. However, despite these problems, shared work on the creature served as a focus for collaboration and exchange rather than rivalry between these three scientific communities. Not only did the initial interpretation and analysis depend on pre-existing connections between British and American paleontological institutions, but the need for comparative material, recognition and contacts brought British and American scholars into communication and exchange with their counterparts in the Soviet Union. This article examines these processes. It first uses these excavations as a comparative case-study of different manifestations of colonial science in this period, examining how scholars in the Britain, the Russian Empire and the United States used formal and informal colonial links to Asia to pursue new research. It then moves to examine how the common problem of reconstructing this giant animal drew metropolitan scientific communities together, at least for a time. The construction of the Baluchitherium and Indricotherium illustrates the drives to expand research both imperially and internationally in the early-twentieth century, but also the continual problems in resources, institutionalization, transport and communication that could run up against scientific work. PMID:25537636

  16. Cosmic Spider is Good Mother

    NASA Astrophysics Data System (ADS)

    2006-04-01

    Hanging above the Large Magellanic Cloud (LMC) - one of our closest galaxies - in what some describe as a frightening sight, the Tarantula nebula is worth looking at in detail. Also designated 30 Doradus or NGC 2070, the nebula owes its name to the arrangement of its brightest patches of nebulosity that somewhat resemble the legs of a spider. This name, of the biggest spiders on Earth, is also very fitting in view of the gigantic proportions of the celestial nebula - it measures nearly 1,000 light years across! ESO PR Photo 11/06 ESO PR Photo 13b/06 Tarantula's Central Cluster, R136 The Tarantula nebula is the largest emission nebula in the sky and also one of the largest known star-forming regions in all the Milky Way's neighbouring galaxies. Located about 170,000 light-years away, in the southern constellation Dorado (The Swordfish), it can be seen with the unaided eye. As shown in this image obtained with the FORS1 multi-mode instrument on ESO's Very Large Telescope, its structure is fascinatingly complex, with a large number of bright arcs and apparently dark areas in between. Inside the giant emission nebula lies a cluster of young, massive and hot stars, denoted R 136, whose intense radiation and strong winds make the nebula glow, shaping it into the form of a giant arachnid. The cluster is about 2 to 3 million years old, that is, almost from 'yesterday' in the 13.7 billion year history of the Universe. Several of the brighter members in the immediate surroundings of the dense cluster are among the most massive stars known, with masses well above 50 times the mass of our Sun. The cluster itself contains more than 200 massive stars. ESO PR Photo 11/06 ESO PR Photo 13c/06 The Stellar Cluster Hodge 301 In the upper right of the image, another cluster of bright, massive stars is seen. Known to astronomers as Hodge 301, it is about 20 million years old, or about 10 times older than R136. The more massive stars of Hodge 301 have therefore already exploded as supernovae, blasting material away at tremendous speed and creating a web of entangled filaments. More explosions will come soon - in astronomical terms - as three red supergiants are indeed present in Hodge 301 that will end their life in the gigantic firework of a supernova within the next million years. ESO PR Photo 13d/06 ESO PR Photo 13d/06 Gas Pillars in Tarantula Nebula While some stars are dying in this spidery cosmic inferno, others are yet to be born. Some structures, seen in the lower part of the image, have the appearance of elephant trunks, not unlike the famous and fertile "Pillars of Creation" at the top of which stars are forming. In fact, it seems that stars form all over the place in this gigantic stellar nursery and in all possible masses, at least down to the mass of our Sun. In some places, in a marvellous recycling process, it is the extreme radiation from the hot and massive stars and the shocks created by the supernova explosions that has compressed the gas to such extent to allow stars to form. To the right and slightly below the central cluster, a red bubble is visible. The star that blows the material making this bubble is thought to be 20 times more massive, 130 000 times more luminous, 10 times larger and 6 times hotter than our Sun. A possible fainter example of such a bubble is also visible just above the large red bubble in the image. ESO PR Photo 13e/06 ESO PR Photo 13e/06 Red Bubbles in Tarantula Nebula Earlier colour composite images of the Tarantula nebula have been made with other instruments and/or filters at ESO's telescopes, e.g. PR Photo 05a/00 in visual light with FORS2 at the VLT at Paranal, and PR Photos 14a-g/02 and 34a-h/04 with the Wide-Field Imager at the ESO/MPG 2.2-m telescope at La Silla.

  17. India's population--what is being done?

    PubMed

    Maloney, C

    1986-01-01

    Thus far, India's efforts to curtail population growth have consistently failed to meet official targets. The crude birthrate (per 1000 population per year) is highest in the belt of 6 Hindi-speaking states, which include Rajasthan (40), Madhya Pradesh (38.5), Uttar Pradesh (38.4), Bihar (37.2), and Haryana (35.9). The rates are slightly lower in the other large North Indian States. The rate is 33.6 for India as a whole according to 1983 data. 3 of the South Indian states have the lowest crude birthrates: Kamataka (28.7), Tamil Nadu (27.8), and Kerata (24.9). Each of India's successive Five Year Plans gave increasingly more emphasis to population control, but the key tactical features have stayed the same. Population control comes under the Ministry of Health and Family Welfare, with family planning services provided through the free health delivery system. The main strategy continues to be to persuade people on an individual basis to accept the small family norm by a wide range of advertising and educational efforts. As of 1986, the family planning establishment had grown to gigantic proportions, employing half a million people in the family planning and health services. The Five Year Plan initiated in July 1985 continues the same approach but with added features. "Green cards" are given to those who accept sterilization after 2 children, allowing them a wide range of benefits such as low interest housing loans, preference in getting housing plots and enterprise loans, and salary increases for government employees. Health workers and other government employees have quotas of persons to motivate for contraceptive acceptance. They receive a small monetary incentive, which they often give to the acceptors so they can maintain their quotas and keep their jobs. The 1986 Revised Strategy for Family Planning is essentially more of the same with family planning more integrated with the health delivery system. Foreign and international donor agencies frequently have placed contradictory pressures on the Indian government, according to their own ideological tendencies. The family planning program is essential despite its faults, which are: bypassing of the natural community; and excessive medicalization and linkage with the health delivery system. In India there is an increasing realization that the achievements of the rural development and family planning programs are marginal relative to the amount of resources committed to them. This is because of the bureaucratic, from-the-top-down bias in which the physical community is neglected. PMID:12315281

  18. Anti-inflammatory, antioxidant, and antimicrobial activities of Cocos nucifera var. typica

    PubMed Central

    2013-01-01

    Background Teas from the husk fiber of Cocos nucifera are used in the folk medicine to treat arthritis and other inflammatory processes. Some works show that some varieties have biological activities. However, one of the main variety of the species, C. nucifera var. typica, known in Brazil as “gigante”, was not studied yet. Thus, this study evaluates if this variety has the anti-inflammatory and antimicrobial activities already reported in other varieties. Methods C. nucifera aqueous crude extract (10, 50, and 100 mg/kg) and the reference drugs morphine (1 mg/kg) and acetylsalicylic acid (100 mg/kg) were evaluated in models of inflammation (formalin-induced licking and subcutaneous air pouch). The antioxidant activity was evaluated by 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) photometric assay and compared with those of the standards (quercetin, rutin, and ascorbic acid). The extract was also screened against Candida albicans, Escherichia coli, Staphylococcus aureus, and methicillin-resistant Staphylococcus aureus (MRSA), in the agar diffusion method. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were determined by the broth micro-dilution assay. Activities of combinations of the extract and antibiotics (methicillin or vancomycin) against MRSA were evaluated using checkerboard assays. Results The extract significantly inhibited the time that the animals spent licking the formalin-injected paws (second phase). The extract also inhibited the inflammatory process induced by subcutaneous carrageenan injection by reducing cell migration, protein extravasation, and TNF-? production. Additionally, the extract showed an antioxidant potential in vitro as good as standards in their antioxidant activity. The extract was active only against S. aureus and MRSA. MIC and the bactericidal concentrations were identical (1,024 ?g/ml). The extract and methicillin acted synergistically against the clinical MRSA isolate, whereas an indifferent effect was detected when the extract was combined with vancomycin. Conclusions The extract exhibits anti-inflammatory activity through the inhibition of the cell migration. The mixture of extract constituents and methicillin could lead to the development of a new combination antibiotic against MRSA infections. PMID:23680079

  19. Why is the Sun Active?

    NASA Astrophysics Data System (ADS)

    Harvey, J.

    1999-05-01

    This fundamental, centuries-old astrophysics question prompted G. E. Hale to create modern solar research. The question (of practical importance to humans) endures and motivates most solar work. What would we tell Hale about recent work if he reappeared among us? Great progress is being made in three areas, all of which he either initiated or strongly influenced. First, Hale would probably be surprised that we can now `look' at activity beneath the surface by studying the oscillations discovered in 1959 using the 60-foot tower telescope that he built in 1907. Such helioseismology research points to the interface between the differentially-rotating convection zone and the almost-uniformly-rotating radiative interior as the nursery of solar activity. Next, Hale's discovery of magnetic fields at the surface of the Sun has led to today's idea that magnetism is at the root of virtually all solar activity phenomena. His interest in vortical (or helical) patterns associated with magnetic fields has recently been reawakened and is now a vigorous area of solar research. The twist of a magnetic field may be almost as important as the field itself in producing violent solar activity. Finally, The study of the solar atmosphere against the solar disk, initiated in Chicago by Hale in 1891, has allowed us to observe the interactions of mass motions and magnetic fields that produce gigantic explosions such as solar flares and coronal mass ejections. These observations strongly suggest that magnetic reconnection is a fundamental and nearly ubiquitous process associated with the activity of the solar atmosphere. Hale vigorously promoted simultaneous advances in observation and theory. Today, a detailed answer to the title of this talk is probably in the literature, but we lack adequate observational tools to test the many published theories and ideas. Hale made revolutionary breakthroughs by applying the latest technology to make new observations that were stimulated by theory and conjecture. We are in a position to apply modern technology, as Hale did a century ago, to make breakthrough observations again. Two exciting next-millennium examples, in the tradition of Hale, are the use of space to get steady, sub-arc-second image quality (the Solar-B mission), and a large-aperture, adaptive-optics-equipped, ground-based telescope for detailed studies of solar MHD phenomena (the Advanced Solar Telescope).

  20. Ductile Faults Control Seismogenic Movement on Oceanic Transforms

    NASA Astrophysics Data System (ADS)

    Lister, G. S.; Tkalcic, H.; Forster, M. A.; McClusky, S.

    2014-12-01

    Structural Geology is about 3D geometry and the symphony of kinematically-coordinated movement. In this case we discuss patterns of violent relative displacement inferred from focal plane data for earthquakes. Systematic stereographic analysis of centroid moment tensor data often shows well-defined orientation groups in scatterplots of fault plane normals and associated slip line vectors. These allow important geodynamic inferences, e.g., we can show that ductile faults control the geometry of oceanic transforms, and that normal fault earthquakes on spreading ridges are usually skewed with respect to adjacent transform faults. To explain this asymmetry requires finite rock strength, but it also means that it is not brittle failure that controls the orientation of oceanic transforms. This asymmetry also requires formation of tilt block geometries reminiscent of Basin-and-Range-style continental extension, systematic offset of earthquake hypocentres from the spreading ridge, and a general complexity in magma-fault interactions that is far beyond what might be expected if ocean-floor spreading is the result of dilating tension-mode fractures in dyke swarms. The role of ductile faulting should be given special mention because mostly it is argued that brittle faults are responsible for earthquakes. Yet many other examples of ductile faults in operation can be inferred, e.g., ductile faults associated with slab drop-off, where slab boudinage leads to extensional ductile faults and seismic activity driven by the pulling away of a relict slab, e.g., beneath the Hindu Kush. Another example might be found by close examination of the tectonic significance of the lowermost of the double (or paired) seismic zones such as can be seen in cross-sections of the subducting slab beneath Japan. The lowermost of the paired seismic zones may mark the locus of aseismic ductile shears or detachments formed by slumping of gigantic sheets of rock attempting to slide down the face of actively subducting slabs. Seismogenic activity may be driven by ductile faulting (again related to boudinage) of the relatively strong sheet of the subducting slab overlying this movement zone. The role of ductile faulting has been undervalued in earthquake generation, and this data suggests revision of seismotectonic doctrines may be necessary.

  1. Solar and Drag Sail Propulsion: From Theory to Mission Implementation

    NASA Technical Reports Server (NTRS)

    Johnson, Les; Alhorn, Dean; Boudreaux, Mark; Casas, Joe; Stetson, Doug; Young, Roy

    2014-01-01

    Solar and drag sail technology is entering the mainstream for space propulsion applications within NASA and around the world. Solar sails derive propulsion by reflecting sunlight from a large, mirror- like sail made of a lightweight, reflective material. The continuous sunlight pressure provides efficient primary propulsion without the expenditure of propellant or any other consumable, allowing for very high V maneuvers and long-duration deep space exploration. Drag sails increase the aerodynamic drag on Low Earth Orbit (LEO) spacecraft, providing a lightweight and relatively inexpensive approach for end-of-life deorbit and reentry. Since NASA began investing in the technology in the late 1990's, significant progress has been made toward their demonstration and implementation in space. NASA's Marshall Space Flight Center (MSFC) managed the development and testing of two different 20-m solar sail systems and rigorously tested them under simulated space conditions in the Glenn Research Center's Space Power Facility at Plum Brook Station, Ohio. One of these systems, developed by L'Garde, Inc., is planned for flight in 2015. Called Sunjammer, the 38m sailcraft will unfurl in deep space and demonstrate solar sail propulsion and navigation as it flies to Earth-Sun L1. In the interim, NASA MSFC funded the NanoSail-D, a subscale drag sail system designed for small spacecraft applications. The NanoSail-D flew aboard the Fast Affordable Science and Technology SATellite (FASTSAT) in 2010, also developed by MSFC, and began its mission after it was was ejected from the FASTSAT into Earth orbit, where it remained for several weeks before deorbiting as planned. NASA recently selected two small satellite missions as part of the Advanced Exploration Systems (AES) Program, both of which will use solar sails to enable their scientific objectives. Lunar Flashlight, managed by JPL, will search for and map volatiles in permanently shadowed Lunar craters using a solar sail as a gigantic mirror to steer sunlight into the shaded craters. The Near Earth Asteroid (NEA) Scout mission will use the sail as primary propulsion allowing it to survey and image one or more NEA's of interest for possible future human exploration. Both are planned for launch in 2017. As the technology matures, solar sails will increasingly be used to enable science and exploration missions that are currently impossible or prohibitively expensive using traditional chemical and electric rockets. For example, the NASA Heliophysics Decadal Survey identifies no less than three such missions for possible flight before the mid-2020's. Solar sail propulsion technology is no longer an intesting theoretical possibility; it has been demonstrated in space and is now a critical technology for science and solar system exploration.

  2. The distribution of an illustrated timeline wall chart and teacher's guide of 20th century physics

    SciTech Connect

    Schwartz, Brian

    2000-12-26

    The American Physical Society's part of its centennial celebration in March of 1999 decided to develop a timeline wall chart on the history of 20th century physics. This resulted in eleven consecutive posters, which when mounted side by side, create a 23-foot mural. The timeline exhibits and describes the millstones of physics in images and words. The timeline functions as a chronology, a work of art, a permanent open textbook, and a gigantic photo album covering a hundred years in the life of the community of physicists and the existence of the American Physical Society. Each of the eleven posters begins with a brief essay that places a major scientific achievement of the decade in its historical context. Large portraits of the essays' subjects include youthful photographs of Marie Curie, Albert Einstein, and Richard Feynman among others, to help put a face on science. Below the essays, a total of over 130 individual discoveries and inventions, explained in dated text boxes with accompanying images, form the backbone of the timeline. For ease of comprehension, this wealth of material is organized into five color-coded story lines the stretch horizontally across the hundred years of the 20th century. The five story lines are: Cosmic Scale, relate the story of astrophysics and cosmology; Human Scale, refers to the physics of the more familiar distances from the global to the microscopic; Atomic Scale, focuses on the submicroscopic world of atoms, nuclei and quarks; Living World, chronicles the interaction of physics with biology and medicine; Technology, traces the applications of physic to everyday living. Woven into the bottom border of the timeline are period images of significant works of art, architecture, and technological artifacts such as telephones, automobiles, aircraft, computers, and appliances. The last poster, covering the years since 1995, differs from the others. Its essay concerns the prospect for physics into the next century, and is illustrated with pictures of promising award winning high school students who, it is hoped, will be the leading researchers of physics in the decades ahead. Appropriately the last entries in the timeline are not achievements but open questions to be answered in the future.

  3. Deterministic Tectonic Origin Tsunami Hazard Analysis for the Eastern Mediterranean and its Connected Seas

    NASA Astrophysics Data System (ADS)

    Necmioglu, O.; Meral Ozel, N.

    2014-12-01

    Accurate earthquake source parameters are essential for any tsunami hazard assessment and mitigation, including early warning systems. Complex tectonic setting makes the a priori accurate assumptions of earthquake source parameters difficult and characterization of the faulting type is a challenge. Information on tsunamigenic sources is of crucial importance in the Eastern Mediterranean and its Connected Seas, especially considering the short arrival times and lack of offshore sea-level measurements. In addition, the scientific community have had to abandon the paradigm of a ''maximum earthquake'' predictable from simple tectonic parameters (Ruff and Kanamori, 1980) in the wake of the 2004 Sumatra event (Okal, 2010) and one of the lessons learnt from the 2011 Tohoku event was that tsunami hazard maps may need to be prepared for infrequent gigantic earthquakes as well as more frequent smaller-sized earthquakes (Satake, 2011). We have initiated an extensive modeling study to perform a deterministic Tsunami Hazard Analysis for the Eastern Mediterranean and its Connected Seas. Characteristic earthquake source parameters (strike, dip, rake, depth, Mwmax) at each 0.5° x 0.5° size bin for 0-40 km depth (total of 310 bins) and for 40-100 km depth (total of 92 bins) in the Eastern Mediterranean, Aegean and Black Sea region (30°N-48°N and 22°E-44°E) have been assigned from the harmonization of the available databases and previous studies. These parameters have been used as input parameters for the deterministic tsunami hazard modeling. Nested Tsunami simulations of 6h duration with a coarse (2 arc-min) and medium (1 arc-min) grid resolution have been simulated at EC-JRC premises for Black Sea and Eastern and Central Mediterranean (30°N-41.5°N and 8°E-37°E) for each source defined using shallow water finite-difference SWAN code (Mader, 2004) for the magnitude range of 6.5 - Mwmax defined for that bin with a Mw increment of 0.1. Results show that not only the earthquakes resembling the well-known historical earthquakes such as AD 365 or AD 1303 in the Hellenic Arc, but also earthquakes with lower magnitudes do constitute to the tsunami hazard in the study area.

  4. G. Marconi: A Data Relay Satellite for Mars Communications

    NASA Astrophysics Data System (ADS)

    Dionisio, C.; Marcozzi, M.; Landriani, C.

    2002-01-01

    Mars has always been a source of intrigue and fascination. Recent scientific discoveries have stimulated this longstanding interest, leading to a renaissance in Mars exploration. Future missions to Mars will be capable of long-distance surface mobility, hyperspectral imaging, subsurface exploration, and even life-detection. Manned missions and, eventually, colonies may follow. No mission to the Red Planet stands alone. New scientific and technological knowledge is passed on from one mission to the next, not only improving the journey into space, but also providing benefits here on Earth. The Mars Relay Network, an international constellation of Mars orbiters with relay radios, directly supports other Mars missions by relaying communications between robotic vehicles at Mars and ground stations on Earth. The ability of robotic visitors from Earth to explore Mars will take a gigantic leap forward in 2007 with the launch of the Guglielmo Marconi Orbiter (GMO), the first spacecraft primarily dedicated to providing communication relay, navigation and timing services at Mars. GMO will be the preeminent node of the Mars Relay Network. GMO will relay communications between Earth and robotic vehicles near Mars. GMO will also provide navigation services to spacecraft approaching Mars. GMO will receive transmissions from ground stations on Earth at X-band and will transmit to ground stations on Earth at X- and Ka-bands. GMO will transmit to robotic vehicles at Mars at UHF and receive from these vehicles at UHF and X-band. GMO's baseline 4450 km circular orbit provides complete coverage of the planet for telecommunication and navigation support. GMO will arrive at Mars in mid-2008, just before the NetLander and Mars Scout missions that will be its first users. GMO is designed for a nominal operating lifetime of 10 years and will support nominal commanding and data acquisition, as well as mission critical events such as Mars Orbit Insertion, Entry, Descent and Landing, and Mars Ascent Vehicle launch and Orbiting Sample Canister detection for the Mars Sample Return mission. The GMO mission is a close collaboration between the Italian and American national space agencies and two implementing organizations: Alenia Spazio in Italy and JPL in the United States. As the Italian prime contractor, Alenia Spazio is to design and fabricate the spacecraft bus, integrate the Italian and JPL payloads, support integration of the spacecraft with the launch vehicle, support launch, and conduct mission operations. GMO will use Alenia' s PRIMA spacecraft bus in a deep space configuration. The PRIMA bus is a new design concept, developed under ASI funding, that combines flexibility, low cost and high efficiency. Its modular design makes it adaptable for several classes of missions, including interplanetary.

  5. Genesis and formation oil and gas fields (Azerbaijan)

    NASA Astrophysics Data System (ADS)

    Poletayev, Alexander

    2010-05-01

    The large amount of material of HC isotope composition of over 330 samples allow to restore the history of oil and gas deposits formation within the South-Caspian Depression. Maps of isotope composition changes according to area extent, as well as graphs of HC distribution depending upon stratigraphic age, including rocks, graphs of isotope composition change on sampling depth were compiled for HC study and oil-gas deposits formation. Comparison of mud volcanoes gases, oil and gas fields, gas-hydrates and bottom sediments were conducted. Gases genesis according to M. Shoelle and A. James methodic were studied. Model of area paleoconstruction was studied. Two stages of formation were distinguished as a result of gases study of various forms of their manifestation (gases of mud volcanoes, oil and gas fields, gas hydrate, bottom sediments) as well as isotope gases composition distribution in area of extent including stratigraphic age of deposits, depth of sampling and application of M. Shoelle and A. James. There were determined basic ways of HC migration as well as estimated oil-gas content prospective. The first stage has begun in the underlying PS deposits and continued up to PS deposits. At this stage one various kind of tectonic fluctuations can observed. The second stage of HC formation has started from PS and characterised with a change of geodynamic conditions in region. Avalanche sedimentation, predominance of descending movements over ascending ones promoted the accumulation of thick sediments in PS age. As a result of sediments accumulation and tectonic processes (down warping) in the deep-seated basin led to the complication of thermobaric conditions in the sedimentary series. The studied chemical and HC gases isotope composition showed that basic source of oil and gas formation is located in the deep areas of central and near-flank parts of depression. HC migration has mainly occurred upward. Study of HC migration trend in time and area as well as areas of generation etc. allows to reveal some structures where there is evidence of HC accumulation with large and gigantic reserves.

  6. The origins of dragon-kings and their occurrence in society

    NASA Astrophysics Data System (ADS)

    Malkov, Artemy; Zinkina, Julia; Korotayev, Andrey

    2012-11-01

    A society is a medium with a complex structure of one-to-one relations between people. Those could be relations between friends, wife-husband relationships, relations between business partners, and so on. At a certain level of analysis, a society can be regarded as a gigantic maze constituted of one-to-one relationships between people. From a physical standpoint it can be considered as a highly porous medium. Such media are widely known for their outstanding properties and effects like self-organized criticality, percolation, power-law distribution of network cluster sizes, etc. In these media supercritical events, referred to as dragon-kings, may occur in two cases: when increasing stress is applied to a system (self-organized criticality scenario) or when increasing conductivity of a system is observed (percolation scenario). In social applications the first scenario is typical for negative effects: crises, wars, revolutions, financial breakdowns, state collapses, etc. The second scenario is more typical for positive effects like emergence of cities, growth of firms, population blow-ups, economic miracles, technology diffusion, social network formation, etc. If both conditions (increasing stress and increasing conductivity) are observed together, then absolutely miraculous dragon-king effects can occur that involve most human society. Historical examples of this effect are the emergence of the Mongol Empire, world religions, World War II, and the explosive proliferation of global internet services. This article describes these two scenarios in detail beginning with an overview of historical dragon-king events and phenomena starting from the early human history till the last decades and concluding with an analysis of their possible near future consequences on our global society. Thus we demonstrate that in social systems dragon-king is not a random outlier unexplainable by power-law statistics, but a natural effect. It is a very large cluster in a porous percolation medium. It occurs as a result of changes in external conditions, such as supercritical load, increase in system elements’ sensitivity, or system connectivity growth.

  7. Nanotechnology in agriculture: prospects and constraints

    PubMed Central

    Mukhopadhyay, Siddhartha S

    2014-01-01

    Attempts to apply nanotechnology in agriculture began with the growing realization that conventional farming technologies would neither be able to increase productivity any further nor restore ecosystems damaged by existing technologies back to their pristine state; in particular because the long-term effects of farming with “miracle seeds”, in conjunction with irrigation, fertilizers, and pesticides, have been questioned both at the scientific and policy levels, and must be gradually phased out. Nanotechnology in agriculture has gained momentum in the last decade with an abundance of public funding, but the pace of development is modest, even though many disciplines come under the umbrella of agriculture. This could be attributed to: a unique nature of farm production, which functions as an open system whereby energy and matter are exchanged freely; the scale of demand of input materials always being gigantic in contrast with industrial nanoproducts; an absence of control over the input nanomaterials in contrast with industrial nanoproducts (eg, the cell phone) and because their fate has to be conceived on the geosphere (pedosphere)-biosphere-hydrosphere-atmosphere continuum; the time lag of emerging technologies reaching the farmers’ field, especially given that many emerging economies are unwilling to spend on innovation; and the lack of foresight resulting from agricultural education not having attracted a sufficient number of brilliant minds the world over, while personnel from kindred disciplines might lack an understanding of agricultural production systems. If these issues are taken care of, nanotechnologic intervention in farming has bright prospects for improving the efficiency of nutrient use through nanoformulations of fertilizers, breaking yield barriers through bionanotechnology, surveillance and control of pests and diseases, understanding mechanisms of host-parasite interactions at the molecular level, development of new-generation pesticides and their carriers, preservation and packaging of food and food additives, strengthening of natural fibers, removal of contaminants from soil and water, improving the shelf-life of vegetables and flowers, clay-based nanoresources for precision water management, reclamation of salt-affected soils, and stabilization of erosion-prone surfaces, to name a few. PMID:25187699

  8. The effect of volume exclusion on the formation of DNA minicircle networks: implications to kinetoplast DNA

    NASA Astrophysics Data System (ADS)

    Diao, Y.; Hinson, K.; Sun, Y.; Arsuaga, J.

    2015-10-01

    Kinetoplast DNA (kDNA) is the mitochondrial of DNA of disease causing organisms such as Trypanosoma Brucei (T. Brucei) and Trypanosoma Cruzi (T. Cruzi). In most organisms, KDNA is made of thousands of small circular DNA molecules that are highly condensed and topologically linked forming a gigantic planar network. In our previous work we have developed mathematical and computational models to test the confinement hypothesis, that is that the formation of kDNA minicircle networks is a product of the high DNA condensation achieved in the mitochondrion of these organisms. In these studies we studied three parameters that characterize the growth of the network topology upon confinement: the critical percolation density, the mean saturation density and the mean valence (i.e. the number of mini circles topologically linked to any chosen minicircle). Experimental results on insect-infecting organisms showed that the mean valence is equal to three, forming a structure similar to those found in medieval chain-mails. These same studies hypothesized that this value of the mean valence was driven by the DNA excluded volume. Here we extend our previous work on kDNA by characterizing the effects of DNA excluded volume on the three descriptive parameters. Using computer simulations of polymer swelling we found that (1) in agreement with previous studies the linking probability of two minicircles does not decrease linearly with the distance between the two minicircles, (2) the mean valence grows linearly with the density of minicircles and decreases with the thickness of the excluded volume, (3) the critical percolation and mean saturation densities grow linearly with the thickness of the excluded volume. Our results therefore suggest that the swelling of the DNA molecule, due to electrostatic interactions, has relatively mild implications on the overall topology of the network. Our results also validate our topological descriptors since they appear to reflect the changes in the physical properties of the polymeric chains and at the same time remain faithful to their description of kDNA.

  9. The propagation of the shock wave from a strong explosion in a plane-parallel stratified medium: the Kompaneets approximation

    NASA Astrophysics Data System (ADS)

    Olano, C. A.

    2009-11-01

    Context: Using certain simplifications, Kompaneets derived a partial differential equation that states the local geometrical and kinematical conditions that each surface element of a shock wave, created by a point blast in a stratified gaseous medium, must satisfy. Kompaneets could solve his equation analytically for the case of a wave propagating in an exponentially stratified medium, obtaining the form of the shock front at progressive evolutionary stages. Complete analytical solutions of the Kompaneets equation for shock wave motion in further plane-parallel stratified media were not found, except for radially stratified media. Aims: We aim to analytically solve the Kompaneets equation for the motion of a shock wave in different plane-parallel stratified media that can reflect a wide variety of astrophysical contexts. We were particularly interested in solving the Kompaneets equation for a strong explosion in the interstellar medium of the Galactic disk, in which, due to intense winds and explosions of stars, gigantic gaseous structures known as superbubbles and supershells are formed. Methods: Using the Kompaneets approximation, we derived a pair of equations that we call adapted Kompaneets equations, that govern the propagation of a shock wave in a stratified medium and that permit us to obtain solutions in parametric form. The solutions provided by the system of adapted Kompaneets equations are equivalent to those of the Kompaneets equation. We solved the adapted Kompaneets equations for shock wave propagation in a generic stratified medium by means of a power-series method. Results: Using the series solution for a shock wave in a generic medium, we obtained the series solutions for four specific media whose respective density distributions in the direction perpendicular to the stratification plane are of an exponential, power-law type (one with exponent k=-1 and the other with k =-2) and a quadratic hyperbolic-secant. From these series solutions, we deduced exact solutions for the four media in terms of elemental functions. The exact solution for shock wave propagation in a medium of quadratic hyperbolic-secant density distribution is very appropriate to describe the growth of superbubbles in the Galactic disk. Member of the Carrera del Investigador Científico del CONICET, Argentina.

  10. Accretion Disks around Young Stars: An Observational Perspective

    NASA Astrophysics Data System (ADS)

    Ménard, F.; Bertout, C.

    Accretion disks are pivotal elements in the formation and early evolution of solar-like stars. On top of supplying the raw material, their internal conditions also regulate the formation of planets. Their study therefore holds the key to solve this long standing mystery: how did our Solar System form? This chapter focuses on observational studies of the circumstellar environment, and in particular of circumstellar disks, associated with pre-main sequence solar-like stars. The direct measurement of disk parameters poses an obvious challenge: at the distance of the typical star forming regions ( e.g. 140 pc for Taurus), a planetary system like ours (with diameter simeq50 AU out to Pluto, but excluding the Kuiper belt which could extend much farther out) subtends only 0.35''. Yet its surface brightness is low in comparison to the bright central star and high angular and high contrast imaging techniques are required if one hopes to resolve and measure these protoplanetary disks. Fortunately, capable instruments providing 0.1'' resolution or better and high contrast have been available for just about 10 years now. They are covering a large part of the electromagnetic spectrum, from the UV/Optical with HST and the near-infrared from ground-based adaptive optics systems, to the millimetric range with long-baseline radio interferometers. It is therefore not surprising that our knowledge of the structure of the disks surrounding low-mass stars has made a gigantic leap forward in the last decade. In the following pages we will attempt to describe, in a historical perpective, the road that led to the idea that most solar-like stars are surrounded by an accretion disk at one point in their early life and how, nowadays, their structural and physical parameters can be estimated from direct observations. We will follow by a short discussion of a few of the constraints available regarding the evolution and dissipation of these disks. This last topic is particularly relevant today to understand the mechanism leading to the formation of planets.

  11. Attitude Determination and Control Systems

    NASA Technical Reports Server (NTRS)

    Starin, Scott R.; Eterno, John

    2011-01-01

    In the year 1900, Galveston, Texas, was a bustling community of approximately 40,000 people. The former capital of the Republic of Texas remained a trade center for the state and was one of the largest cotton ports in the United States. On September 8 of that year, however, a powerful hurricane struck Galveston island, tearing the Weather Bureau wind gauge away as the winds exceeded 100 mph and bringing a storm surge that flooded the entire city. The worst natural disaster in United States history even today the hurricane caused the deaths of between 6000 and 8000 people. Critical in the events that led to such a terrible loss of life was the lack of precise knowledge of the strength of the storm before it hit. In 2008, Hurricane Ike, the third costliest hurricane ever to hit the United States coast, traveled through the Gulf of Mexico. Ike was gigantic, and the devastation in its path included the Turk and Caicos Islands, Haiti, and huge swaths of the coast of the Gulf of Mexico. Once again, Galveston, now a city of nearly 60,000, took the direct hit as Ike came ashore. Almost 200 people in the Caribbean and the United States lost their lives; a tragedy to be sure, but far less deadly than the 1900 storm. This time, people were prepared, having received excellent warning from the GOES satellite network. The Geostationary Operational Environmental Satellites have been a continuous monitor of the world's weather since 1975, and they have since been joined by other Earth-observing satellites. This weather surveillance to which so many now owe their lives is possible in part because of the ability to point accurately and steadily at the Earth below. The importance of accurately pointing spacecraft to our daily lives is pervasive, yet somehow escapes the notice of most people. But the example of the lives saved from Hurricane Ike as compared to the 1900 storm is something no one should ignore. In this section, we will summarize the processes and technologies used in designing and operating spacecraft pointing (i.e. attitude) systems.

  12. Leveraging the International Polar Year Legacy: Providing Historical Perspective for IPY Education, Outreach and Communication Efforts

    NASA Astrophysics Data System (ADS)

    Tsukernik, M.; McCaffrey, M. S.

    2006-12-01

    As the International Polar Year 2007-2008 (IPY) is fast approaching, it is important to look back and learn from the previous experience. Over 125 years ago, when an Austrian explorer and naval officer Lt. Karl Weyprecht called for an international yearlong intensive effort to study the Polar Regions, he probably never imagined that his model for international collaboration would become so widely popular. Frustrated by the lack of coordinated, international collaboration in research activities, Weyprecht proposed an intensive burst of research activity over the course of at least a year. The first IPY began in 1882 with 12 nations establishing 13 stations in the Arctic and 2 in the Southern Hemisphere. The initial yearlong plan did not go beyond data collection. However, the idea lived in the minds of scientists worldwide and the second IPY followed the first one 50 years later. By 1932, technology evolved significantly, and on top of ground-based meteorological and geophysical measurements, data collection also included radiosonde and acoustic atmospheric measurements. Occurring during a global economic depression, and between world wars, the second IPY faced many challenges. However, 40 permanent stations were established, some of which are still active. Scientific exploration also reached remote frontiers from Antarctica to the Earth's ionosphere. Less than a decade after the WWII, the idea of the next IPY started to circulate in scientific circles. The world was focused on space exploration and the word "polar" seemed too narrow for the gigantic projects planned for the 1957. That is why the initial idea of the third IPY evolved into the International Geophysical Year (IGY), although polar regions were still a major focus. The success of the IGY is almost overwhelming the first Earth orbiting satellites, a traverse of Antarctica, a discovery of the Radiation Belt, a series of science education films about IGY activities and research themes are just a few examples. In addition to the scientific breakthroughs, the IGY was an extremely successful political event. In the middle of the Cold War, scientists from competing countries had a unique chance to meet and share their research ideas. This peaceful collaboration resulted in 1961 signing of the Antarctic Treaty, protecting the sixth continent for scientific, non-military research. Many AGU scientists indicate that the IGY educational programs, along with the rapid development of science and technology following the IGY inspired their career choice.

  13. Green Lake Landslide and other giant and very large postglacial landslides in Fiordland, New Zealand

    NASA Astrophysics Data System (ADS)

    Hancox, Graham T.; Perrin, Nick D.

    2009-06-01

    Green Lake Landslide is an ancient giant rock slide in gneiss and granodiorite located in the deeply glaciated Fiordland region of New Zealand. The landslide covers an area of 45 km 2 and has a volume of about 27 km 3. It is believed to be New Zealand's largest landslide, and possibly the largest landslide of its type on Earth. It is one of 39 known very large (10 6-10 7 m 3) and giant (?10 8 m 3) postglacial landslides in Fiordland discussed in the paper. Green Lake Landslide resulted in the collapse of a 9 km segment of the southern Hunter Mountains. Slide debris moved up to 2.5 km laterally and 700 m vertically, and formed a landslide dam about 800 m high, impounding a lake about 11 km long that was eventually infilled with sediments. Geomorphic evidence supported by radiocarbon dating indicates that Green Lake Landslide probably occurred 12?000-13?000 years ago, near the end of the last (Otira) glaciation. The landslide is described, and its geomorphic significance, age, failure mechanism, cause, and relevance in the region are discussed, in relation to other large landslides and recent earthquake-induced landslides in Fiordland. The slope failure occurred on a low-angle fault zone undercut by glacial erosion, and was probably triggered by strong shaking (MM IX-X) associated with a large (? M 7.5-8) earthquake, on the Alpine Fault c. 80 km to the northwest. Geology was a major factor that controlled the style and size of Green Lake landslide, and in that respect it is significantly different from most other gigantic landslides. Future large earthquakes on the Alpine Fault in Fiordland are likely to trigger more very large and giant landslides across the region, causing ground damage and devastation on a scale that has not occurred during the last 160 years, with potentially disastrous effects on towns, tourist centres, roads, and infrastructure. The probability of such an event occurring within the next 50 years may be as high as 45%.

  14. Immune Defenses of the Invasive Apple Snail Pomacea canaliculata (Caenogastropoda, Ampullariidae): Phagocytic Hemocytes in the Circulation and the Kidney

    PubMed Central

    Vega, Israel A.; Castro-Vazquez, Alfredo

    2015-01-01

    Hemocytes in the circulation and kidney islets, as well as their phagocytic responses to microorganisms and fluorescent beads, have been studied in Pomacea canaliculata, using flow cytometry, light microscopy (including confocal laser scanning microscopy) and transmission electron microscopy (TEM). Three circulating hemocyte types (hyalinocytes, agranulocytes and granulocytes) were distinguished by phase contrast microscopy of living cells and after light and electron microscopy of fixed material. Also, three different populations of circulating hemocytes were separated by flow cytometry, which corresponded to the three hemocyte types. Hyalinocytes showed a low nucleus/cytoplasm ratio, and no apparent granules in stained material, but showed granules of moderate electron density under TEM (L granules) and at least some L granules appear acidic when labeled with LysoTracker Red. Both phagocytic and non-phagocytic hyalinocytes lose most (if not all) L granules when exposed to microorganisms in vitro. The phagosomes formed differed whether hyalinocytes were exposed to yeasts or to Gram positive or Gram negative bacteria. Agranulocytes showed a large nucleus/cytoplasm ratio and few or no granules. Granulocytes showed a low nucleus/cytoplasm ratio and numerous eosinophilic granules after staining. These granules are electron dense and rod-shaped under TEM (R granules). Granulocytes may show merging of R granules into gigantic ones, particularly when exposed to microorganisms. Fluorescent bead exposure of sorted hemocytes showed phagocytic activity in hyalinocytes, agranulocytes and granulocytes, but the phagocytic index was significantly higher in hyalinocytes. Extensive hemocyte aggregates ('islets') occupy most renal hemocoelic spaces and hyalinocyte-like cells are the most frequent component in them. Presumptive glycogen deposits were observed in most hyalinocytes in renal islets (they also occur in the circulation but less frequently) and may mean that hyalinocytes participate in the storage and circulation of this compound. Injection of microorganisms in the foot results in phagocytosis by hemocytes in the islets, and the different phagosomes formed are similar to those in circulating hyalinocytes. Dispersed hemocytes were obtained after kidney collagenase digestion and cell sorting, and they were able to phagocytize fluorescent beads. A role for the kidney as an immune barrier is proposed for this snail. PMID:25893243

  15. Model of explosive eruptions of water vapor and dust on icy satellites

    NASA Astrophysics Data System (ADS)

    Fateev, E. G.

    2008-04-01

    The possibility of generating water vapor and other gaseous products during nonvolcanic explosive eruptions in lithospheres of icy satellites is discussed. Explosive eruptions of ice, with its fragmentation into micro-and nanofragments, can occur in the extensive deep layers of such icy satellites as Europa, Ganymede, Enceladus, etc., if giant cracks are episodically formed in the lithospheres of these satellites. Such cracks can be produced by tidal forces, synchronous resonances of satellites, or especially powerful impacts. The model is based on the recently obtained experimental evidence that explosive ice instability (Bridgman effect) is formed at a strong nonuniform compression in the regions of high pressures and low temperatures. Water films, the thicknesses of which reach several microns, can be formed during the process of the mutual friction of ice fragments during their quasi-liquid flow at the instant of an explosive eruption. About 1-10 dm3 of a water film can be produced in 1 m3 of erupted ice fragments. Water vapor can be formed from a water film when this water boils up after a rapid pressure drop as a result of an ice-water mixture eruption from cracks. A certain amount of gaseous products in the form of hydrogen, oxygen, and ammonia molecules and radicals on their basis can be generated during the sputtering induced by electrons and ions and the dissociation of nanofragments of ice during the process of ice explosive fragmentation as a result of fracto-, tribo-, and secondary emission. The estimates indicate that the volume of water vapor erupted on satellites can be larger than that of discharged ionized gases by a factor of not less than 105-107. Water vapor and microscopic ice fragments can be erupted from cracks in the lithospheres of small Enceladus-type satellites at velocities higher than the second cosmic velocity. Gaseous products generated in such episodic processes can, most probably, substantially contribute to the density of the atmosphere that exists on small icy satellites, but can only insignificantly contribute to this density on large satellites. The stick-slip motions of the most condensed plumes of water vapor and dust, normal to the satellite surface, along the mouths of gigantic cracks may indicate that the proposed model is realistic. Such wanderings of water vapor plumes can result in the synchronous motions of thermal patches on the satellite surface along crack mouths at velocities of about 10 km/h.

  16. Energetic runaway electrons emitted from streamers

    NASA Astrophysics Data System (ADS)

    Celestin, S. J.; Pasko, V. P.

    2010-12-01

    Streamers are filamentary plasmas, which are driven by highly nonlinear space charge waves. In tips of streamers, intense electric fields are produced, and the generation of runaway electrons in these discharges has been identified and discussed in the literature for more than two decades [Babich, Sov. Phys. Dokl., 263, 76, 1982, and references therein]. It has been proposed that with total potential differences on the order of tens of MV available in streamer zones of lightning leaders, during a highly transient negative corona flash stage of the development of negative stepped leader, electrons with energies 2-8 keV ejected from streamer tips near the leader head can be further accelerated to energies of hundreds of keV and possibly to several tens of MeV [Moss et al., JGR, 111, A02307, 2006]. It has been proposed that these energetic electrons may be responsible, through the bremsstrahlung process, for the generation of hard X-rays observed from ground and satellites [e.g., Fishman et al., Science, 264, 1313, 1994; Inan et al., GRL, 23, 1017, 1996; Moore et al., GRL, 28, 2141, 2001; Dwyer et al., GRL, 32, L01803, 2005; Smith et al., Science, 307, 1085, 2005; Cummer et al., GRL, 32, L08811, 2005; and references therein]. The current observations and theories of transient luminous events occurring above cloud tops and termed blue and gigantic jets are converging towards a clear connection between jet discharges and streamer zones of lightning leaders [Krehbiel et al., Nature Geosci., 1, 233, 2008; and references therein] and it has been suggested that the thermal runaway electron process operating in leaders may contribute to production of terrestrial gamma ray flashes from the jet discharges [Moss et al., 2006]. In the present work, we combine our recently developed Monte Carlo code simulating the propagation of electrons in air with energies varying from sub-eV to MeV [Celestin and Pasko, CEDAR Workshop, Boulder, CO, W2 ECCR245, 20-25 June, 2010] with streamer fluid models [e.g., Bourdon et al., PSST, 16, 656, 2007] in order to demonstrate the strong impact of the ambient conditions and dynamical features of the streamer discharges on the emission of high energy electrons eventually leading to X-ray emissions. We describe a mechanism in which electrons with energies 10 times higher than those obtained in [Moss et al., 2006] are ejected from tips of streamers and are directly capable of further acceleration in streamer zone of negative leaders.

  17. Europe's battery: The making of the Alpine energy landscape, 1870-1955

    NASA Astrophysics Data System (ADS)

    Landry, Marc D., II

    This study examines the environmental history of hydropower development in the Alps from the mid-nineteenth to the mid-twentieth centuries. Analyzing government archival files, associational journals, conference proceedings, and published contemporary material from several Alpine countries, it seeks to determine how and why Europeans modified the Alpine landscape to generate hydropower, and to explore the consequences of these decisions. I argue that during this time period, Europeans thoroughly transformed the Alpine environment, creating what I call "Europe's Battery": a gigantic system for storing hydropower and distributing it on a continental scale. This study shows how nineteenth-century innovations in energy technology contributed to a dramatic shift in the perception of the Alps as a landscape of "white coal." It demonstrates how at the outset of electrification, Europeans modified Alpine waterways on an unprecedented scale in order to tap into the power of flowing Alpine water. I show how after the turn of the twentieth century, Europeans took advantage of the unique mountain environment to store water, first by converting existing lakes into reservoirs. The practice countered what was perceived to be the greatest disadvantage of white coal: its climate-influenced inconstancy. This study shows the importance of war, and especially the First World War, in the forging of the new Alpine landscape. Finally, this study illustrates how from the interwar period to the aftermath of the Second World War, Europeans put the finishing touches on the new Alpine energy landscape by creating large reservoirs behind dams and feeding Alpine hydroelectricity into a burgeoning European electricity grid. By 1955 the Alps had become one of the most important energy landscapes in Europe. This history of the Alpine energy landscape contributes to a number of historiographical fields. It represents an important chapter in the environmental history of one of the world's most iconic landscapes. It sheds light on the hydroelectric energy transition and shows the environmental impacts of electrification. Finally the history of Europe's Battery illuminates an alternative regional history of energy development and industrialization in Europe, one based on water and electricity and not coal.

  18. The Italian drilling project of the Mont Blanc road tunnel in the late fifties: an example of no geological care and lack of ethics in carrying out a big work.

    NASA Astrophysics Data System (ADS)

    Gosso, Guido; Croce, Giuseppe; Matteucci, Ruggero; Peppoloni, Silvia; Piacente, Sandra; Wasowski, Janusz

    2013-04-01

    In the first decade after the Second World War Italy was rushing to recover a positive role among European countries; basic needs as road communications with European neighbours became main priorities. The necessity of a rapid connection with South-eastern France, a subject already debated between the two nations over more than 50 years, appeared then on first line; the two countries convened on a joint investment for the construction of a tunnel across the international border of Mont Blanc, along the shortest track between Courmayeur and Chamonix. The political agreements were in favour of the quickest start of the drilling operations and such obligation imposed on the Italian side an impoverishment of the project content, specially concerning geological issues. No surveys were performed on fracture systems, cataclastic zones and faults, on the few rock ridges standing above the tunnel line and outcropping through thick talus cones, moraines, ice tongues and their related ice plateaus. Metasediments, migmatites and poorly foliated granites were to be drilled. Three Italian academics were allowed by the drilling company to track the working progress and collect rocks for comparison with other Alpine types; they mapped the lithology and the fault zonesall along the freshly excavated tunnel; the results of such survey appeared after the end of works. Geologists from Florence University published the surface granite faulting pattern 20 years after the road tunnel became operative. Such geological cares could have located the risky zones in time for the tunnel project, mitigating the catastrophic effects of sudden drainage of subglacial water from the Vallée Blanche ice plateau (Ghiacciaio del Gigante) at progression 3800m, that caused dramatic accidents and affected negatively the economy of the drilling. Also the wallrock temperature drops, measured during the drill, should have warned the company management on the location of dangerous fracture zones. Anxiety of national renaissance probably committed the Italian team to a fast conclusion, skipping attention from geological urgencies. But did attitudes change since then? This late episode gives us the opportunity to reflect on the necessity of making politicians seriously aware of the importance of geology when carrying out big works, to impose by law more effective policies and make interrelations between the involved professionals mandatory. Firm geoethic principles should guide choices and decisions in projects of great environmental impact.

  19. The Impossible cave in the Classical Karst

    NASA Astrophysics Data System (ADS)

    Cucchi, F.; Boschin, W.; Visintin, L.; Zini, L.

    2009-04-01

    The Impossible Cave has been discovered, near Trieste (Classical Karst, northern Italy) in the year 2004 during road construction and up to today has been explored for more than 3 km. This cave opens in Paleocene - Eocene pure limestones, similarly to the ones situated in Rosandra Valley (placed a few hundreds meters from the entrance of this cave) that is the better developed cave system in the Karst of Trieste. In the area where the Impossible Cave has been found, the calcareous strata form a knee fold and overtrusts the marly arenaceous strata of the Eocene Flysch of Trieste with a large NW-SE fault. The cave is situated approximately 500 m from the contact between the limestones and the Flysch. The large galleries that form the Impossible Cave are better developed in an E-W general direction but that is the result of an alternate conditioning by dinaric and anti-dinaric structures; in the other side, the smaller galleries are orientated NW-SE, parallel to Flysch and limestones contact and to the direction of the strata. The most particular feature of the Impossible Cave is the great underground karst forms development, which is better represented by a large cavern that for size is close to the one of the Grotta Gigante that is the bigger tourist cave worldwide. A peculiar aspect of the Impossible Cave is that the surface where the cave has been discovered is characterized by the absence of well developed dolines or sinkholes and the classical karst morphologies are very few or poorly developed. On the surface it is impossible to recognize the main structural features which interest the rock massif; however, hypogean voids show clearly that structural rock mass trim is the main factor which due the speleogenesis. In the mean time the Impossible Cave differs from theoretical cave models for the Classical Karst and that's the reason of the nickname of impossible. By comparing it to the main caves in the areas it seems developed in a direction and at an altitude not related to the previously known hydrogeological evolution of this region. Explorations of this cave have indicated that signs of the Messinian crisis are not found or limited to few caverns that in the terminal parts have sub vertical walls; different structural features drove the formation of main and secondary galleries and it probably occurred at different times.

  20. Landslide disaster avoidance: learning from Leyte

    NASA Astrophysics Data System (ADS)

    Davies, T. R.

    2006-12-01

    On 17 February 2006 a gigantic rockslide triggered a debris avalanche that overran the barangay Guinsaugon, St. Bernard in Southern Leyte Province, Philippines, burying 154 victims, with 990 missing including 246 school children. Even with satellite imagery, GIS-based landslide susceptibility modelling and real-time meteorological and seismic data analysis, scientific prediction of every potentially fatal landslide is not possible in most parts of the world. This is particular the case in steep, unstable, densely-populated country in which heavy rain is common. So how can further events of this type be prevented from turning into disasters? A number of precursory phenomena were noted by local inhabitants at Guinsaugon: a crack around the slope that failed was noticed in May 2005; coconut trees near the northern foot of the landslide scarp began to lean increasingly in the down-slope direction in December 2005; a slope around the northern edge of the 17 February 2006 landslide scarp failed on December 17, 2005; in the 9 days prior to the rockslide, 640 mm of rain fell; 450 mm in a 3-day period. Such phenomena are commonly reported by local inhabitants before large landslides (e.g. Elm, Mayunmarca, and many others). In many cases, therefore, it is in principle possible for local people to avoid the consequences of the landslide if they know enough to act appropriately in response to the precursory phenomena. For this possibility to be realized, appropriate information must be provided to and assimilated by the local population. Useful ways of achieving this include pamphlets, video, TV and radio programs and visits from civil defence personnel. The information must be properly presented; scientific language will be ineffective. A communication pyramid, leading from government agencies to local leaders, can facilitate the rapid availability of the information to all potentially susceptible communities. If science can determine those areas not vulnerable to landslide disasters, that is potentially advantageous. However the next landslide may be next week, so the information initiative cannot wait for science: lives will not be saved while the pamphlets are in a box. Keywords: Leyte landslide; precursory phenomena; disaster avoidance; community awareness.

  1. Brazilian and Mexican experiences in the study of incipient domestication

    PubMed Central

    2014-01-01

    Background Studies of domestication enables a better understanding of human cultures, landscape changes according to peoples’ purposes, and evolutionary consequences of human actions on biodiversity. This review aimed at discussing concepts, hypotheses, and current trends in studies of domestication of plants, using examples of cases studied in regions of Mesoamerica and Brazil. We analyzed trends of ethnobiological studies contributing to document processes of domestication and to establish criteria for biodiversity conservation based on traditional ecological knowledge. Methods Based on reviewing our own and other authors’ studies we analyzed management patterns and evolutionary trends associated to domestication occurring at plant populations and landscape levels. Particularly, we systematized information documenting: ethnobotanical aspects about plant management and artificial selection mechanisms, morphological consequences of plant management, population genetics of wild and managed plant populations, trends of change in reproduction systems of plants associated to management, and other ecological and physiological aspects influenced by management and domestication. Results Based on the analysis of study cases of 20 native species of herbs, shrubs and trees we identified similar criteria of artificial selection in different cultural contexts of Mexico and Brazil. Similar evolutionary trends were also identified in morphology (selection in favor of gigantism of useful and correlated parts); organoleptic characteristics such as taste, toxicity, color, texture; reproductive biology, mainly breeding system, phenological changes, and population genetics aspects, maintenance or increasing of genetic diversity in managed populations, high gene flow with wild relatives and low structure maintained by artificial selection. Our review is a first attempt to unify research methods for analyzing a high diversity of processes. Further research should emphasize deeper analyses of contrasting and diverse cultural and ecological contexts for a better understanding of evolution under incipient processes of domestication. Conclusion Higher research effort is particularly required in Brazil, where studies on this topic are scarcer than in Mexico but where diversity of human cultures managing their also high plant resources diversity offer high potential for documenting the diversity of mechanisms of artificial selection and evolutionary trends. Comparisons and evaluations of incipient domestication in the regions studied as well as the Andean area would significantly contribute to understanding origins and diffusion of the experience of managing and domesticating plants. PMID:24694009

  2. A review on anthropogenic impact to the Micro Prespa lake and its damages

    NASA Astrophysics Data System (ADS)

    Frasheri, N.; Pano, N.; Frasheri, A.; Beqiraj, G.; Bushati, S.; Taska, E.

    2012-04-01

    Paper presents the results of the integrated and multidisciplinary studies for investigation of the anthropogenic damages to Albanian part of the transborder Micro Prespa Lake. Remote sensing with Landsat images was used for identification of environmental changes in time for the period 1970 - 2010. Micro Prespa Lake is lake with international status, as Ramsar Convection, International Park and Special Protection Area-79/409/EEC. According to the studies, investigations and analyses, the following were concluded: Devolli River- Micro Prespa Lake irrigation system was not scientifically supported by environmental engineering, hydroeconomy and International Rights principles. It does work according to the projected parameters, and also, doesn't supply the agricultural needs. About of 10 % of the water volume, discharges by Devolli River in Micro Prespa Lake during the winter, is taken from this lake for the irrigation in summer. Great surface of Albanian part of Micro Prespa Lake is destroyed. The other part of the lake is atrophied and the habitat and biodiversity are damaged. Important and unique species of fish, birds and plants of national and international values are risked. The underground karstic connection ways for water circulation are blocked. There are ruining the historic values of the area, such the encient Treni cave from the Bronze Age. The Albanian part of the Micro Prespa Lake has been damaged by the human activities. A huge amount of 1,2 million cubic meters alluvium has been deposited on the lake bottom and lakeshore, which was transported by the Devolli River waters, since 1974. This river waters, rich in alluvium and organic coal material from outcropped geological formations, also absorbed free chemical toxic remains by the drainage of Devolli farm ground, which have changed the chemical features of the lake water and degrading it. Micro Prespa Lake communicates with Macro Prespa Lake, and together with Ohrid Lake. Blockage of underground karstic connection ways has diminished not only the components of the lake water balance, but also the decreasing yield of the underground springs, that supply the Ohrid lake and drinkable water springs. The Albanian part of the Micro Prespa Lake plays the role of a gigantic decanter. This is an unprecedented case, not only in Albanian but also in Balkan and World hydrography. Devolli river alluvium deposited in Micro Prespa Lake caused the otherwise of territory of Republic of Albania in this area. Albania will not have any part in this lake after some years. The social and public opinion in Albania, must be conscious for the otherwise of Albanian territory, which in the case of Micro Prespa Lake has a national and international negative effect on destructions of a transborder lake, defendey by Europian Convents.

  3. Global Monitoring RSEM System for Crop Production by Incorporating Satellite-based Photosynthesis Rates and Anomaly Data of Sea Surface Temperature

    NASA Astrophysics Data System (ADS)

    Kaneko, D.; Sakuma, H.

    2014-12-01

    The first author has been developing RSEM crop-monitoring system using satellite-based assessment of photosynthesis, incorporating meteorological conditions. Crop production comprises of several stages and plural mechanisms based on leaf photosynthesis, surface energy balance, and the maturing of grains after fixation of CO2, along with water exchange through soil vegetation-atmosphere transfer. Grain production in prime countries appears to be randomly perturbed regionally and globally. Weather for crop plants reflects turbulent phenomena of convective and advection flows in atmosphere and surface boundary layer. It has been difficult for scientists to simulate and forecast weather correctly for sufficiently long terms to crop harvesting. However, severely poor harvests related to continental events must originate from a consistent mechanism of abnormal energetic flow in the atmosphere through both land and oceans. It should be remembered that oceans have more than 100 times of energy storage compared to atmosphere and ocean currents represent gigantic energy flows, strongly affecting climate. Anomalies of Sea Surface Temperature (SST), globally known as El Niño, Indian Ocean dipole, and Atlantic Niño etc., affect the seasonal climate on a continental scale. The authors aim to combine monitoring and seasonal forecasting, considering such mechanisms through land-ocean biosphere transfer. The present system produces assessments for all continents, specifically monitoring agricultural fields of main crops. Historical regions of poor and good harvests are compared with distributions of SST anomalies, which are provided by NASA GSFC. Those comparisons fairly suggest that the Worst harvest in 1993 and the Best in 1994 relate to the offshore distribution of low temperature anomalies and high gaps in ocean surface temperatures. However, high-temperature anomalies supported good harvests because of sufficient solar radiation for photosynthesis, and poor harvests because of insufficient precipitation. Integrated rates of photosynthesis on prime grains with planted areas were compared with the SST anomalies in poor and good harvests years. Other factors for poor harvest such as rainfall, solar radiation in addition to the intensity of winds as a measure of pressure perturbations need to be studied.

  4. Sprite-producing Convective Storms within the Colorado Lightning Mapping Array

    NASA Astrophysics Data System (ADS)

    Lyons, W. A.; Cummer, S. A.; Rison, W.; Krehbiel, P. R.; Lang, T. J.; Rutledge, S. A.; Lu, G.; Stanley, M. A.; Ashcraft, T.; Nelson, T. E.

    2012-12-01

    The multi-year, multi-institution effort entitled Physical Origins of Coupling to the Upper Atmosphere from Lightning (PhOCAL), has among its goals to qualitatively understand the meteorology and lightning flash characteristics that produce the unusual and/or very energetic lightning responsible for phenomena such as sprites, halos, elves, blue jets and gigantic jets, collectively known as Transient Luminous Events (TLEs). A key task is to obtain simultaneous video, ideally with a high-speed imager (HSI), of both a TLE and its parent lightning discharge, within the domain of a 3-D Lightning Mapping Array (LMA). While conceptually simple, this task is logistically quite complicated. In 2012, a new 15-station Colorado LMA (COLMA) became operational, covering northeastern Colorado, with the Yucca Ridge Field Station (YRFS) near its western edge. The National Charge Moment Change Network (CMCN), which since 2007 has been documenting sprite-class +CGs (those with impulse change moment changes >100 C km), indicates that a strong gradient of energetic +CGs exists west-to-east through the COLMA, with the most likely region for sprite-producing storms being in the COLMA eastern fringes (western Kansas and Nebraska). Yet, on 8 and 25 June, 2012, intense convective systems formed in the COLMA along and just east of the Front Range, producing severe weather and intense lightning. On the 8th, four sprite parent +CGs were captured at 3000 fps from YRFS with the sprites confirmed by dual (conventional speed) cameras in New Mexico. In a second storm on the 25th, viewing conditions prevented +CG video acquisition, but sprites were logged over the COLMA and detailed reconstructions of the discharges are being made. The parent discharges often began as upward negative leaders propagating into a mid-level positive charge layer at 8-10 km. They often originated within or near the convective core before expanding outward into a stratiform region and involving several hundred square kilometers, to be followed by +CG and strong continuing currents. LMA indications of recoil leaders appear confirmed by some high-speed video. These storms were somewhat smaller than the typical sprite-bearing MCS. The storm structures will be categorized using GOES IR, NEXRAD reflectivity, NLDN lightning data, CMCN impulse charge moment data, and full charge moment charge retrievals. The sprite parent CG discharges will be cataloged along with their points of origin, the height and volume from which charge is removed, the charge lowered to ground, and the continuing current characteristics. These CGs will be placed in the context of the storms' meteorological structure and evolution.

  5. Lymnaea palustris and Lymnaea fuscus are potential but uncommon intermediate hosts of Fasciola hepatica in Sweden

    PubMed Central

    2013-01-01

    Background Lymnaea palustris and L. fuscus are members of the European stagnicolines (Gastropoda: Lymnaeidae). The role of stagnicolines in transmission of Fasciola hepatica has been often proposed. To assess the possible relationship between these two stagnicolines and F. hepatica in Sweden, field monitoring in parallel with experimental infections of L. palustris and L. fuscus were conducted. Methods Stagnicoline snails were collected and identified on pastures grazed by either sheep or cattle on four farms suffering from fasciolosis in Sweden during 2011–2012. Field-collected L. palustris and L. fuscus were examined for F. hepatica DNA by PCR. In the laboratory, different age groups of L. palustris, L. fuscus and G. truncatula were each exposed to two F. hepatica miracidia and main infection characteristics were obtained. Results One field-collected L. palustris (out of n?=?668) contained F. hepatica as determined by PCR. On the other hand, stagnicolines artificially exposed to F. hepatica miracidia resulted in successful infection with fully differentiated cercariae, but only in juvenile snails (size, 1–2 mm at exposure) and with a prevalence of 51% and 13% in L. palustris and L. fuscus, respectively. In contrast, 90% of juvenile (size, 1–2 mm) and 92% of preadult G. truncatula (size, ? 2-4 mm), respectively, were successfully infected. Delayed, reduced and/or no spontaneous cercarial shedding was observed in the two stagnicolines when compared to G. truncatula. However, at snail dissection most cercariae from L. fuscus and L. palustris were able to encyst similarly to those from G. truncatula. Conclusion Both L. fuscus and L. palustris can sustain larval development of F. hepatica but with an apparent level of age resistance. The finding of a single F. hepatica positive specimen of L. palustris, together with infection characteristics from the experimental infection, suggest that L. palustris is a more suitable snail vector of F. hepatica than L. fuscus. The reduced growth observed in both stagnicolines was contrary to the ‘parasitic gigantism’ theory. Overall, it seems that the epidemiological role of L. palustris in transmission of F. hepatica in Sweden is likely to be much lower than for G. truncatula. PMID:23985077

  6. Assessing Glacier Hazards At Ghiacciaio Del Belvedere, Macugnaga, Italian Alps

    NASA Astrophysics Data System (ADS)

    Haeberli, W.; Chiarle, M.; Mortara, G.; Mazza, A.

    The uppermost section of the Valle Anzasca behind and above the community of Macugnaga in the Italian Alps is one of the most spectacular high-mountain land- scapes in Europe, with gigantic rock walls and numerous steep hanging glaciers. Its main glacier, Ghiacciaio del Belvedere at the foot of the huge Monte Rosa east face, is a heavily debris-covered glacier flowing on a thick sediment bed. Problems with floods, avalanches and debris flows from this ice body have been known for extended time periods. Most recently, however, the evolution of this highly dynamic environ- ment has become more dramatic. An outburst of Lago delle Locce, an ice-dammed lake at the confluenec of the tributary Ghiacciaio delle Locce with Ghiacciaio del Belvedere, caused heavy damage in 1979 and necessitated site investigation and con- struction work to be done for flood protection. The intermittent glacier growth ten- dency in the 1970es induced strong bulging of the glacier surface and, in places, caused the glacier tongue to override historical morains and to destroy newly-grown forest stands. A surge-type flow acceleration started in the lower parts of the Monte- Rosa east face during summer 2000, leading to strong crevassing and deformation of Ghiacciaio del Belvedere and extreme bulging of its orographic right margin. High water pressure and accelerated movement lasted into winter 2001/2002: the ice now started overriding the LIA moraine near Rifugio Zamboni of the CAI. In addition but rather independently, a most active detachment zone for rock falls and debris flows developed for several years now in the east face of Monte Rosa, somewhat more to the south of the accelerated glacier movement and at an altitude where relatively warm permafrost must be expected. Besides the scientific interest in these phenomena, the growing hazard potential to the local infrastructure must be considered seriously. Es- pecially potentials for the destabilization of large rock and ice masses in the east face of Monte Rosa, for interruption of the access trail to the Rifugio Zamboni by overrid- ing and/or collapse of the lateral moraine, for impacts by ice invading various instal- lations (cable car, restaurant, ski runs, trails) near the moraine hill of Belvedere, and for sudden outbursts of pressurized subglacial water or the newly formed supraglacial lake must be envisaged.

  7. Volcanic eruptions, global change and evolution of species

    NASA Astrophysics Data System (ADS)

    Courtillot, V.

    2007-12-01

    Our group proposed in 1986 that the Deccan traps of India had been co-eval with the Cretaceous-Tertiary mass extinction, had lasted less than 800 kyears, straddling the KT. In 1995, Bhandari and colleagues showed that the iridium level marking the Chicxulub impact could be found in the Deccan and was sandwiched between flows, demonstrating that they were co-eval events but that volcanism had started first and could not be a consequence of impact. Since then, many groups have contributed to dating more precisely continental flood basalts around the world and found that there was almost a one to one correspondance between flood basalts and mass extinctions (but not impacts, except for the KT) : for a recent review see Courtillot and Renne (2003). In recent years, a number of significant advances have been made. It has been shown in the case of the historically large but geologically very small Icelandic Laki eruption of 1783 that such eruptions could inject large amounts of sulfate aerosols all the way to the stratosphere and have a global impact on climate : therefore, effusive basaltic volcanism on a large scale could alter climate (our group with Frédéric Fluteau and Anne-Lise Chenet and Steve Self with Thor Thordarson). Petrologic, volcanological, paleomagnetic, paleontological and geochronologic studies of the entire 3000m thick Deccan pile have been resumed (mainly our group, that of Self with Mike Widdowson and Anne Jay, and that of Gerta Keller). The result is that the thick lava pile actually erupted in a relatively small number of gigantic pulses (with mega-flows up to 10000 km3 in volume having erupted in decades !). Field evidence has been given that flows could extend over almost 1000km, and paleontological and K-Ar dating now reveals a history of mainly two mega-pulses having occurred, one just prior to the KT the second somewhat afterwards explaining the long delay of recovery of species from the catastrophe. There is little doubt now that the KT catastrophe would have occurred even if the impact (which did have a significant additionnal effect) had not struck, and that the impact could not have generated a mass extinction if volcanism had not already been going on. Finally, global change during these periods of anomalous volcanism may provide interesting benchmarks for modelling of more current potential global change, and geologists be a major help to climate modelers.

  8. Maximum Earthquake Magnitude Assessments by Japanese Government Committees (Invited)

    NASA Astrophysics Data System (ADS)

    Satake, K.

    2013-12-01

    The 2011 Tohoku earthquake (M 9.0) was the largest earthquake in Japanese history and such a gigantic earthquake was not foreseen around Japan. After the 2011 disaster, various government committees in Japan have discussed and assessed the maximum credible earthquake size around Japan, but their values vary without definite consensus. I will review them with earthquakes along the Nankai Trough as an example. The Central Disaster Management Council, under Cabinet Office, set up a policy for the future tsunami disaster mitigation. The possible future tsunamis are classified into two levels: L1 and L2. The L2 tsunamis are the largest possible tsunamis with low frequency of occurrence, for which saving people's lives is the first priority with soft measures such as tsunami hazard maps, evacuation facilities or disaster education. The L1 tsunamis are expected to occur more frequently, typically once in a few decades, for which hard countermeasures such as breakwater must be prepared. The assessments of L1 and L2 events are left to local governments. The CDMC also assigned M 9.1 as the maximum size of earthquake along the Nankai trough, then computed the ground shaking and tsunami inundation for several scenario earthquakes. The estimated loss is about ten times the 2011 disaster, with maximum casualties of 320,000 and economic loss of 2 trillion dollars. The Headquarters of Earthquake Research Promotion, under MEXT, was set up after the 1995 Kobe earthquake and has made long-term forecast of large earthquakes and published national seismic hazard maps. The future probability of earthquake occurrence, for example in the next 30 years, was calculated from the past data of large earthquakes, on the basis of characteristic earthquake model. The HERP recently revised the long-term forecast of Naknai trough earthquake; while the 30 year probability (60 - 70 %) is similar to the previous estimate, they noted the size can be M 8 to 9, considering the variability of past earthquakes. The Nuclear Regulation Authority, established in 2012, makes independent decisions based on the latest scientific knowledge. They assigned maximum credible earthquake magnitude of 9.6 for Nankai an Ryukyu troughs, 9.6 for Kuirl-Japan trench, and 9.2 for Izu-Bonin trench.

  9. Condiciones Físicas en Nebulosas Gaseosas

    NASA Astrophysics Data System (ADS)

    Luridiana, V.

    1999-03-01

    El presente trabajo se ha enfocado a determinar y entender las condiciones físicas en una variedad de objetos nebulares, prestando particular atención al problema de la determinación de las abundancias químicas. Para este fin, hemos utilizado métodos analíticos en algunos casos, y modelos numéricos de fotoionización en otros. El objetivo general del trabajo es proveer de una visión amplia de las herramientas teórico-observacionales que se utilizan para la determinación de la estructura de temperatura y densidad de las regiones fotoionizadas, poniendo en evidencia posibles fuentes de errores sistemáticos y sus consecuencias para la determinación de las abundancias químicas, y proponiendo métodos para corregirlos. Los resultados principales de este trabajo est´n listados a continuación: a) Se discute el problema de la discrepancia entre T(C III) y T(O III) en las nebulosas planetarias, y se muestra como tal discrepancia implica probablemente la presencia de fluctuaciones de temperatura. Debido a que la temperatura de O++ es muy afectada por fluctuaciones de temperatura, se recomienda usar la temperatura de C++ para determinar la abundancia de carbono. b) Presentamos dos nuevos métodos para determinar la temperatura electrónica en nebulosas planetarias, basados en la medición de las intensidades de las líneas de He I. Las temperaturas que se obtienen a partir de estos métodos son menores que aquellas que se obtienen a partir de las líneas de [O III], implicando la presencia de fluctuaciones espaciales de temperatura. Despreciando las fluctuaciones de temperatura, se obtienen valores sesgados de las abundancias químicas. Determinamos las abundancias en las nebulosas planetarias de tipo I de algunos de los elementos más importantes, tomando en cuenta las fluctuaciones de temperatura. c) Presentamos modelos numéricos de las dos regiones H II extragalácticas gigantes NGC 2363 y NGC 5461. Con el modelaje numérico, pretendemos acotar las carácteristicas principales de las nubes ionizadas (distribución espacial del gas, estructura de ionización y de temperatura) y de los cúmulos ionizantes (función inicial de masa, historia de formación estelar, edad). En ambos casos, mostramos que con modelos numéricos calculados para el valor de metalicidad que se determina a partir de la temperatura de [O III], no es posible reproducir el espectro de emisión observado, y que para reproducir las restricciones más robustas es necesario subir la metalicidad de los modelos por un factor de 2. Esto constituye una fuerte indicación en favor de la presencia de fluctuaciones de temperatura. d) Para poder comparar los modelos numéricos con los datos observacionales. mostramos la importancia de corregir las predicciones de los modelos por el sesgo introducido por el tamaío finito de la rendija.

  10. Effects of probiotic administration on zebrafish development and reproduction.

    PubMed

    Carnevali, O; Avella, M A; Gioacchini, G

    2013-07-01

    As the consumption of probiotics increases worldwide, scientists focus on identifying bacterial strains able to improve human life quality and evidence the biological pathways affected by probiotic treatment. In this review, some recent observations on the effects of changes of microbiota on zebrafish metabolism were discussed. In addition, the effects of Lactobacillus rhamnosus - a component of the human gut microflora - as a diet supplement on Danio rerio were presented. When administered chronically, L. rhamnosus may affect larval development and the physiology of reproductive system in the zebrafish model. It was hypothesized exogenous L. rhamnosus accelerates larval growth and backbone development by acting on insulin-like growth factors-I (igfI) and -II (igfII), peroxisome proliferator activated receptors-? and -?, (ppar?,?) vitamin D receptor-? (vdr?) and retinoic acid receptor-? (rar?). Gonadal differentiation was anticipated at 6weeks together with a higher expression of gnrh3 at the larval stage when L. rhamnosus was administered throughout development. Moreover, brood stock alimented with a L. rhamnosus-supplemented diet showed better reproductive performances as per follicles development, ovulated oocytes quantification and embryos quality. A plausible involvement of factors such as leptin, and kiss1 and 2 in the improvements was concluded. The observations made on the physiology of female reproduction were correlated with the gene expression of a gigantic number of factors as the aromatase cytochrome p 19 (cyp19a), the vitellogenin (vtg) and the ? isoform of the E2 receptor (er?), luteinizing hormone receptor (lhr), 20-? hydroxysteroid dehydrogenase (20?-hsd), membrane progesterone receptors ? and ?, cyclin B, activin?A1, smad2, transforming growth factor ?1 (tgf?1), growth differentiation factor9 (gdf9) and bone morphogenetic protein15 (bmp15.) A model in which the exogenous L. rhamnosus in the digestive tract of zebrafish from the first days of life through sexual maturation positively influences the physiological performances of zebrafish was evidenced and a number of pathways that might be influenced by the presence of this human probiotic strain were proposed. PMID:23500006

  11. Sadness, tragedy and mass disaster in Oklahoma City: providing critical incident stress debriefings to a community in crisis.

    PubMed

    Davis, J A

    1996-04-01

    Shortly after 09:00 h on 19 April 1995, the Alfred P. Murrah Federal Building, located in downtown Oklahoma City, was devastated with a bomb blast of such gigantic proportions that it was heard 60 miles away in neighbouring Norman, Oklahoma. Oklahomans routinely commuting to work on that sunny Wednesday morning went about their business as usual. A crude bomb chemically comprised of various organic compounds, chemical fertilizer, ammonium nitrate and diesel fuel, weighing an estimated 4800 pounds or more, was transported in a vehicle the size of a truck. It blew open a crater 6-8 ft deep in the street floor. The Murrah Federal Building was impacted immediately; floors, windows, communication equipment and almost all the innocent victims inside were razed to the ground. Outside the building, as far as 10 blocks away or more, hundreds of victims lay hurt, seriously injured or dead from shards of glass that flew from office windows hundreds of feet above the street floor. Without warning, the initial impact of the bomb immediately devastated the entire city. People were in a state of shock, disbelief and denial; acute symptoms of post traumatic stress disorder (PTSD) were commonplace. Oklahomans, 'numb' from the impact of the critical incident and ill-equipped to handle the chaos of such catastrophic proportions, struggled to regain control of their lives as friends, family and loved ones went unaccounted for or were found critically injured, dying or already dead. The critical incident on 19 April demanded the immediate attention of the nation, to come to the aid of the Oklahomans who were in desperate need. By 1 June, the exhaustive investigations revealed that 30 office buildings in downtown Oklahoma City had to be condemned, and as many as 300 others were damaged. In addition, 168 people had been found dead including 19 children and one nurse working as an emergency services rescue worker. Approximately 490 other victims had been reported injured from the blast. Countless others have been traumatised by the critical event and will need professional attention and care for weeks, months and years to come. The final extent of the impact on Oklahoma City is yet unknown and may never realistically be estimated in terms of personal trauma, loss and grief. PMID:8716419

  12. NEA Scout and Lunar Flashlight: Two NearTerm Interplanetary CubeSat Missions

    NASA Technical Reports Server (NTRS)

    Johnson, Les

    2015-01-01

    NASA is developing two small satellite missions as part of the Advanced Exploration Systems (AES) Program, both of which will use a solar sail to enable their scientific objectives. Solar sails reflect sunlight from a large, mirror-like sail made of a lightweight, highly reflective material to provide thrust. This continuous photon pressure provides propellantless thrust, allowing for very high delta V maneuvers in space. Lunar Flashlight, managed by the NASA Jet Propulsion Laboratory, will search for and map volatiles in permanently shadowed lunar craters using a solar sail as a gigantic mirror to steer sunlight into them, then examine the reflected light with a spectrometer. The Lunar Flashlight spacecraft will also use the solar sail to maneuver into a lunar polar orbit. The mission will demonstrate a low-cost capability to explore, locate and estimate the size and composition of ice deposits on the Moon. The Near Earth Asteroid (NEA) Scout mission, managed by the NASA Marshall Space Flight Center will survey and image a Near Earth Asteroid for possible future human exploration using a smallsat propelled by a solar sail. Detections of NEAs are expected to grow in the near future, offering increasing target opportunities. Obtaining and analyzing relevant data about these bodies via robotic precursors before committing a crew to visit them is essential. The NEA Scout spacecraft is nearly identical to the one being developed for Lunar Flashlight, with the science instrument package being the primary difference. The NEA Scout solar sail will provide the primary propulsion taking the 6U cubesat from near the Earth to its final asteroid destination and the Lunar Flashlight sail will provide the propulsion necessary for its spacecraft to enter lunar orbit. Both projects will use an 85 m2 solar sail developed by NASA MSFC. The NEA Scout and Lunar Flashlight flight systems are based on a 6U cubesat form factor, with a stowed envelope of 10 x 20 x 30 cm and a mass of less than 12 kg. The solar sail for NEA Scout and Lunar Flashlight will be based on the technology developed and flown by the NASA NanoSail-D and The Planetary Society's Lightsail-A. Four 7 m stainless steel booms wrapped on two spools (two overlapping booms per spool) will be motor deployed and pull the sail from its stowed volume. The sail material will be 3 micron CP1, an aluminized polyimide that was extensively tested for solar sail applications. The sail will spooled rather than Z-folded. This paper will describe both the Lunar Flashlight and NEA Scout missions and their solar sails.

  13. Larger than life: billboard communication in Southeast Asia.

    PubMed

    Barnard, B

    1983-01-01

    Billboards are widely used in Southeast Asia, and especially in Malaysia, Singapore, Indonesia, and Thailand, for delivering persuasive political and commercial messages and for advertising the cinema. Billboards are a cost effective way of communicating with all segments of society including illiterate persons, poor people who cannot afford television sets and radios, rural populations, and diverse ethnic and linguistic groups. Billboards are a form of applied art and are used to deliver temporary messages. Each country has its own billboard traditions and styles, and within each country, commercial, cinema, and political boards also have their own styles. In Indonesia and Thailand, almost all billboards are hand painted and gigantic in size. The paintings are highly realistic and detailed. In Thailand billboards are produced in large studios employing many artists, and the boards cost about US$9.00/square meter or more. The Four Art Studio in Bankok produces commercial boards in Renaissance, Impressionistic, Pop, and Op art styles. Both Indonesia and Thailand were early centers of artistic and cultural influence in Asia, and each country has highly developed art traditions. In Indonesia, the Japanese occupation led to the development of propaganda and nationalistic art. After independence nationalistic art was developed still further. At the present time, socialist-realistism predominates as an art style, and large air brushed political billboards are prominantly displayed throughout the country. In Malaysia and Singapore billboards are small in size. Most of the boards, except those used to advertise the cinema, are printed rather than painted. Neither country has a strong tradition of art. Realism is not stressed in their fine arts nor in their art training. The lack of a realistic art tradition probably accounts for the emphasis placed on printed billboards. Cinema boards are painted but they are not produced by applied artists and are generally mediocre in quality. Political boards in Malaysia generally contain only verbal messages. In Singapore there are few political billboards. In Japan billboards are also widely used. They are sophisticated and usually printed with advanced technological methods. An innovative form of billboard, a 20 meter audiovisual screen, is appearing more and more frequently in Japanese cities. PMID:12339664

  14. Visions of our Planet's Atmosphere, Land and Oceans: NASA/NOAA Electronic Theater 2002

    NASA Technical Reports Server (NTRS)

    Hasler, A. F.; Starr, David (Technical Monitor)

    2002-01-01

    The NASA/NOAA Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to the Olympic Medals Plaza, the new Gateway Center, and the University of Utah Stadium Site of the Olympic Opening and Closing Ceremonies in Salt Lake City. Fly in and through the Park City, and Snow Basin sites of the 2002 Winter Olympic Alpine Venues using 1 m IKONOS "Spy Satellite" data. See the four seasons of the Wasatch Front as observed by Landsat 7 at 15m resolution and watch the trees turn color in the Fall, snow come and go in the mountains and the reservoirs freeze and melt. Go back to the early weather satellite images from the 1960s and see them contrasted with the latest US and international global satellite weather movies Including hurricanes & "tornadoes". See the latest visualizations of spectacular images from NASA/NOAA remote sensing missions like Terra, GOES, TRMM, SeaWiFS, Landsat 7 including new 1 - min GOES rapid scan image sequences of Nov 9th 2001 Midwest tornadic thunderstorms and have them explained. See how High-Definition Television (HDTV) is revolutionizing the way we communicate science. (In cooperation with the American Museum of Natural History in NYC) See dust storms in Africa and smoke plumes from fires in Mexico. See visualizations featured on the covers Of Newsweek, TIME, National Geographic, Popular Science & on National & International Network TV. New computer software. tools allow us to roam & zoom through massive global images e.g. Landsat tours of the US, and Africa, showing desert and mountain geology as well as seasonal changes in vegetation. See animations of the polar ice packs and the motion of gigantic Antarctic Icebergs from SeaWinds data. Spectacular new visualizations of the global atmosphere & oceans are shown. See vertexes and currents in the global oceans that bring up the nutrients to feed tin) algae and draw the fish, whales and fisherman. See the how the ocean blooms in response to these currents and El Nino/La Nina climate changes. See the city lights, fishing fleets, gas flares and biomass burning of the Earth at night observed by the "night-vision" DMSP military satellite. The demonstration is interactively driven by a SGI Octane Graphics Supercomputer with two CPUs, 4 Gigabytes of RAM and 0.5 Terabyte of disk using two projectors across a super sized panoramic 48 foot screen. In addition new HDTV technology will be demonstrated from a portable computer server.

  15. Electronic-Theater 2001: Visions of Our Planet's Atmosphere, Land and Oceans

    NASA Technical Reports Server (NTRS)

    Hasler, Authur; Starr, David OC. (Technical Monitor)

    2001-01-01

    The NASA/NOAA/AMS Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to Wisconsin, Madison and the Monona Terrace Center. Drop in on the Kennedy Space Center and Park City Utah, site of the 2002 Olympics using I m IKONOS "Spy Satellite" data. Go back to the early weather satellite images from the 1960s pioneered by UW. Scientists and see them contrasted with the latest US and International global satellite weather movies including hurricanes & tornadoes. See the latest spectacular images from NASA/NOAA remote sensing missions like Terra GOES, TRMM, SeaWiFS, Landsat 7 that are visualized & explained. See how High Definition Television (HDTV) is revolutionizing the way we communicate science in cooperation with the American Museum of Natural History in NYC. See dust storms in Africa and smoke plumes from fires in Mexico. See visualizations featured on Newsweek, TIME, National Geographic, Popular Science covers & National & International Network TV. New visualization tools allow us to roam & zoom through massive global images eg Landsat tours of the US, Africa, & New Zealand showing desert and mountain geology as well as seasonal changes in vegetation. See animations of the polar ice packs and the motion of gigantic Antarctic Icebergs from SeaWinds data. Spectacular new visualizations of the global atmosphere & oceans are shown. See massive dust storms sweeping across Africa. See vortices and currents in the global oceans that bring up the nutrients to feed tiny plankton and draw the fish, whales and fisherman. See the how the ocean blooms in response to these currents and El Nina/La Nina climate changes. The demonstration is interactively driven by a SGI Onyx 11 Graphics Supercomputer with four CPUs, 8 Gigabytes of RAM and Terabyte of disk. With five projectors on a giant IMAX sized 18 x 72 ft screen. See the city lights, fishing fleets, gas flares and bio-mass burning of the Earth at night observed by the "nightvision" DMSP military satellite.

  16. Visions of our Planet's Atmosphere, Land and Oceans: NASA/NOAA Electronic Theater 2002

    NASA Technical Reports Server (NTRS)

    Hasler, A. F.; Starr, David (Technical Monitor)

    2001-01-01

    The NASA/NOAA Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to the Olympic Medals Plaza, the new Gateway Center, and the University of Utah Stadium Site of the Olympic Opening and Closing Ceremonies in Salt Lake City. Fly in and through the Park City, and Snow Basin sites of the 2002 Winter Olympic Alpine Venues using 1 m IKONOS "Spy Satellite" data. See the four seasons of the Wasatch Front as observed by Landsat 7 at 15m resolution and watch the trees turn color in the Fall, snow come and go in the mountains and the reservoirs freeze and melt. Go back to the early weather satellite images from the 1960s and see them contrasted with the latest US and international global satellite weather movies including hurricanes & "tornadoes". See the latest visualizations of spectacular images from NASA/NOAA remote sensing missions like Terra, GOES, TRMM, SeaWiFS, Landsat 7 including new 1 - min GOES rapid scan image sequences of Nov 9th 2001 Midwest tornadic thunderstorms and have them explained. See how High-Definition Television (HDTV) is revolutionizing the way we communicate science. (In cooperation with the American Museum of Natural History in NYC) See dust storms in Africa and smoke plumes from fires in Mexico. See visualizations featured on the covers of Newsweek, TIME, National Geographic, Popular Science & on National & International Network TV. New computer software tools allow us to roam & zoom through massive global images e.g. Landsat tours of the US, and Africa, showing desert and mountain geology as well as seasonal changes in vegetation. See animations of the polar ice packs and the motion of gigantic Antarctic Icebergs from SeaWinds data. Spectacular new visualizations of the global atmosphere & oceans are shown. See vortexes and currents in the global oceans that bring up the nutrients to feed tiny algae and draw the fish, whales and fisherman. See the how the ocean blooms in response to these currents and El Nino/La Nina climate changes. See the city lights, fishing fleets, gas flares and bio-mass burning of the Earth at night observed by the "night-vision" DMSP military satellite. The demonstration is interactively driven by a SGI Octane Graphics Supercomputer with two CPUs, 4 Gigabytes of RAM and 0.5 Terabyte of disk using two projectors across a super sized panoramic 48 foot screen. In addition new HDTV technology will be demonstrated from a portable computer server.

  17. Olivine in the Southern Isidis Basin

    NASA Technical Reports Server (NTRS)

    2007-01-01

    The Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) took this observation of the transition region between Libya Montes and the Isidis Basin on Mars at 17:16 UTC (12:16 p.m. EST) on January 2, 2007, near 3.6 degrees north latitude, 84.1 degrees east longitude. The image was taken in 544 colors covering 0.36-3.92 micrometers, and shows features as small as 18 meters (60 feet) across. The image is about 11 kilometers (7 miles) wide at its narrowest point.

    The Isidis Basin resulted from of a gigantic impact on the surface of Mars early in the planet's history. The southern rim, where this target is located, is a region of complex geology and part of the planetary dichotomy boundary that separates the older southern highlands from the lower, younger northern plains. The image on the left was constructed from three visible wavelengths (RGB: 0.71, 0.60, 0.53 microns) and is a close approximation of how the surface would appear to the human eye. The image on the right was constructed from three infrared wavelengths (RGB: 2.49, 1.52, 1.08 microns) chosen to highlight variations in the mineralogy of the area. Of interest is that features in this image not only differ in color, but also in texture and morphology. The gray areas absorb similarly at all wavelengths used in this image, but display absorptions at other wavelengths related to the iron- and magesium-rich mineral pyroxene. The reddest areas absorb strongly at the wavelengths used for green and blue, which is attributable to another iron- and magesium-rich mineral, olivine. The brownish areas show subdued mineral absorptions and could represent some type of mixture between the other two materials. The presence of the mineral olivine is particularly interesting because olivine easily weathers to other minerals; thus, its presence indicates either the lack of weathering in this region or relatively recent exposure.

    CRISM's mission: Find the spectral fingerprints of aqueous and hydrothermal deposits and map the geology, composition and stratigraphy of surface features. The instrument will also watch the seasonal variations in Martian dust and ice aerosols, and water content in surface materials -- leading to new understanding of the climate.

    The Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) is one of six science instruments on NASA's Mars Reconnaissance Orbiter. Led by The Johns Hopkins University Applied Physics Laboratory, the CRISM team includes expertise from universities, government agencies and small businesses in the United States and abroad.

  18. Tvashtar in Motion

    NASA Technical Reports Server (NTRS)

    2007-01-01

    This five-frame sequence of New Horizons images captures the giant plume from Io's Tvashtar volcano. Snapped by the probe's Long Range Reconnaissance Imager (LORRI) as the spacecraft flew past Jupiter earlier this year, this first-ever 'movie' of an Io plume clearly shows motion in the cloud of volcanic debris, which extends 330 kilometers (200 miles) above the moon's surface. Only the upper part of the plume is visible from this vantage point -- the plume's source is 130 kilometers (80 miles) below the edge of Io's disk, on the far side of the moon.

    The appearance and motion of the plume is remarkably similar to an ornamental fountain on Earth, replicated on a gigantic scale. The knots and filaments that allow us to track the plume's motion are still mysterious, but this movie is likely to help scientists understand their origin, as well as provide unique information on the plume dynamics.

    Io's hyperactive nature is emphasized by the fact that two other volcanic plumes are also visible off the edge of Io's disk: Masubi at the 7 o'clock position, and a very faint plume, possibly from the volcano Zal, at the 10 o'clock position. Jupiter illuminates the night side of Io, and the most prominent feature visible on the disk is the dark horseshoe shape of the volcano Loki, likely an enormous lava lake. Boosaule Mons, which at 18 kilometers (11 miles) is the highest mountain on Io and one of the highest mountains in the solar system, pokes above the edge of the disk on the right side.

    The five images were obtained over an 8-minute span, with two minutes between frames, from 23:50 to 23:58 Universal Time on March 1, 2007. Io was 3.8 million kilometers (2.4 million miles) from New Horizons; the image is centered at Io coordinates 0 degrees north, 342 degrees west.

    The pictures were part of a sequence designed to look at Jupiter's rings, but planners included Io in the sequence because the moon was passing behind Jupiter's rings at the time.

  19. Tsunami Hazard Analysis for the Eastern Mediterranean and its Connected Seas

    NASA Astrophysics Data System (ADS)

    Necmioglu, Ocal; Meral Ozel, Nurcan

    2015-04-01

    Accurate earthquake source parameters are essential for any tsunami hazard assessment and mitigation, including early warning systems. Complex tectonic setting makes the a priori accurate assumptions of earthquake source parameters difficult and characterization of the faulting type is a challenge. Information on tsunamigenic sources is of crucial importance in the Eastern Mediterranean and its Connected Seas, especially considering the short arrival times and lack of offshore sea-level measurements. In addition, the scientific community have had to abandon the paradigm of a ''maximum earthquake'' predictable from simple tectonic parameters (Ruff and Kanamori, 1980) in the wake of the 2004 Sumatra event (Okal, 2010) and one of the lessons learnt from the 2011 Tohoku event was that tsunami hazard maps may need to be prepared for infrequent gigantic earthquakes as well as more frequent smaller-sized earthquakes (Satake, 2011). We have initiated an extensive modeling study to perform a deterministic Tsunami Hazard Analysis for the Eastern Mediterranean and its Connected Seas. Characteristic earthquake source parameters (strike, dip, rake, depth, Mwmax) at each 0.5° x 0.5° size bin for 0-40 km depth (total of 310 bins) and for 40-100 km depth (total of 92 bins) in the Eastern Mediterranean, Aegean and Black Sea region (30°N-48°N and 22°E-44°E) have been assigned from the harmonization of the available databases and previous studies. These parameters have been used as input parameters for the deterministic tsunami hazard modeling. Nested Tsunami simulations of 6h duration with a coarse (2 arc-min) grid resolution have been simulated at EC-JRC premises for Black Sea and Eastern and Central Mediterranean (30°N-41.5°N and 8°E-37°E) for each source defined using shallow water finite-difference SWAN code (Mader, 2004) for the magnitude range of 6.5 - Mwmax defined for that bin with a Mw increment of 0.1. Results show that not only the earthquakes resembling the well-known historical earthquakes such as AD 365 or AD 1303 in the Hellenic Arc, but also earthquakes with lower magnitudes do constitute to the tsunami hazard in the study area, as indicated also by historical information. A simplified tsunami hazard map is also presented. This work is partially funded by project ASTARTE - Assessment, Strategy And Risk Reduction for Tsunamis in Europe - FP7-ENV2013 6.4-3, Grant 603839.

  20. The interactive sky: a browsable allsky image

    NASA Astrophysics Data System (ADS)

    Tancredi, Gonzalo; Da Rosa, Fernando; Roland, Santiago; Almenares, Luciano; Gomez, Fernando

    2015-08-01

    We are conducting a project to make available panoramas of the night sky of the southern hemisphere, based on a mosaic of hundred of photographs. Each allsky panorama is a giant image composed by hundreds of high-resolution photos taken in the course of one night. The panoramas are accessible with a web-browser and the public is able to zoom on them and to see the sky with better quality than the naked eye. We are preparing 4 sets of panoramas corresponding to the four seasons.The individual images are taken with a 16 Mpixels DLSR camera with a 50 mm lens mounted on a Gigapan EPIC robotic camera mounts. These devices and a autoguiding telescope are mounted in a equatorial telescope mount, which allows us to have exposure of several tens seconds. The images are then processed and stitched to create the gigantic panorama, with typical weight of several GBytes.The limiting magnitude is V~8. The panoramas include more than 50 times more stars those detected with the naked eye.In addition to the allsky panoramas, we embedded higher resolution images of specific regions of interest such as: emission nebulae and dark, open and globular clusters and galaxies; which can be zoomed.The photographs have been acquiring since December 2014 in a dark place with low light pollution in the countryside of Uruguay; which allows us to achieve deep sky objects.These panoramas will be available on a website and can be accessed with any browser.This tool will be available for teaching purposes, astronomy popularization or introductory research. Teacher guides will be developed for educational activities at different educational levels.While there are similar projects like Google Sky, the methodology used to generate the giant panoramas allows a much more realistic view, with a background of continuous sky without sharp edges. Furthermore, while the planetarium software is based on drawings of the stars, our panoramas are based on real images.This is the first project with these characteristics; we hope it will become a reference for browsable allsky images with many web visitors.The project is supported by a grant from the Agencia Nacional de Investigación e Innovación ANII (Uruguay).