Science.gov

Sample records for construction programs c-1

  1. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Constructive ownership of stock. 1.267(c)-1 Section 1.267(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED... the outstanding stock of the M Corporation. The M Corporation in turn owned 80 percent of...

  2. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 3 2014-04-01 2014-04-01 false Constructive ownership of stock. 1.267(c)-1 Section 1.267(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED... 25 percent, of the outstanding stock of the M Corporation. The M Corporation in turn owned 80...

  3. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 3 2012-04-01 2012-04-01 false Constructive ownership of stock. 1.267(c)-1 Section 1.267(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED... 25 percent, of the outstanding stock of the M Corporation. The M Corporation in turn owned 80...

  4. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 3 2011-04-01 2011-04-01 false Constructive ownership of stock. 1.267(c)-1 Section 1.267(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED... 25 percent, of the outstanding stock of the M Corporation. The M Corporation in turn owned 80...

  5. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 3 2013-04-01 2013-04-01 false Constructive ownership of stock. 1.267(c)-1 Section 1.267(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED... 25 percent, of the outstanding stock of the M Corporation. The M Corporation in turn owned 80...

  6. Computer Programs for Construction

    NASA Technical Reports Server (NTRS)

    1978-01-01

    A NASA computer program aids Hudson Engineering Corporation, Houston, Texas in the design and construction of huge petrochemical processing plants like the one shown, which is located at Ju'aymah, Saud Arabia. The pipes handling the flow of chemicals are subject to a variety of stresses, such as weight and variations in temperature. Hudson Engineering uses a COSMIC piping flexibility analysis computer program to analyze and insure the necessary strength and flexibility of the pipes. This program helps the company realize substantial savings in reduced engineering time.

  7. Constructing Programs from Example Computations.

    ERIC Educational Resources Information Center

    Bierman, A. W.; Krishnaswamy, R.

    This paper describes the construction and implementation of an autoprogramming system. An autoprogrammer is an interactive computer programming system which automatically constructs computer programs from example computations executed by the user. The example calculations are done in a scratch pad fashion at a computer display, and the system…

  8. Language constructs for modular parallel programs

    SciTech Connect

    Foster, I.

    1996-03-01

    We describe programming language constructs that facilitate the application of modular design techniques in parallel programming. These constructs allow us to isolate resource management and processor scheduling decisions from the specification of individual modules, which can themselves encapsulate design decisions concerned with concurrence, communication, process mapping, and data distribution. This approach permits development of libraries of reusable parallel program components and the reuse of these components in different contexts. In particular, alternative mapping strategies can be explored without modifying other aspects of program logic. We describe how these constructs are incorporated in two practical parallel programming languages, PCN and Fortran M. Compilers have been developed for both languages, allowing experimentation in substantial applications.

  9. 40 CFR 265.19 - Construction quality assurance program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... that the liners are constructed to meet the hydraulic conductivity requirements of §§ 264.221(c)(1... conductivity requirements must be verified by using in-situ testing on the constructed test fill. The test fill... conductivity requirements of §§ 264.221(c)(1), 264.251(c)(1), and 264.301(c)(1) of this chapter in the...

  10. Constructing Knowledge in Leadership Training Programs

    ERIC Educational Resources Information Center

    Aalsburg Wiessner, Colleen; Gonzalez Sullivan, Leila

    2007-01-01

    This study examined the new learning that occurred in a professional development program for participants who aspire to the community college presidency. Knowledge construction occurred on three levels: personal, professional, and disciplinary. Reframing, embracing, and embodying activities toward knowledge construction were evident, and new…

  11. FELIX construction status and experimental program

    SciTech Connect

    Turner, L.R.; Praeg, W.F.; Knott, M.J.; Lari, R.J.; McGhee, D.G.; Wehrle, R.B.

    1983-01-01

    FELIX (Fusion Electromagnetic Induction Experiment) is an experimental test facility being constructed at Argonne National Laboratory (ANL) for the study of electromagnetic effects in the first wall/blanket/shield (FWBS) systems of fusion reactors. The facility design, construction status, experimental program, instrumentation, and associated computer-code comparisons are described.

  12. Upgrading Programs for Construction Journeymen. Final Report.

    ERIC Educational Resources Information Center

    Franklin, William S.

    The report describes a study of industry-sponsored upgrading programs for journeymen in construction unions. Interviews with union and training officials, as well as 405 journeymen and 99 contractors, revealed that upgrading activities were concentrated in electrical work, carpentry, and the pipe trades, and that both the number of programs and…

  13. Acceptorless Dehydrogenative Coupling of o-Aminobenzamides with the Activation of Methanol as a C1 Source for the Construction of Quinazolinones.

    PubMed

    Li, Feng; Lu, Lei; Liu, Pengcheng

    2016-06-01

    A strategy for the synthesis of quinazolinones via acceptorless coupling of o-aminobenzamides with methanol has been accomplished in the presence of the metal-ligand bifunctional catalyst [Cp*Ir(2,2'-bpyO)(H2O)]. Notably, this research exhibited the potential of transition-metal-catalyzed activation of methanol as a C1 source for the construction of heterocycles. PMID:27210593

  14. Complement Component C1q Programs a Pro-Efferocytic Phenotype while Limiting TNFα Production in Primary Mouse and Human Macrophages

    PubMed Central

    Hulsebus, Holly J.; O’Conner, Sean D.; Smith, Emily M.; Jie, Chunfa; Bohlson, Suzanne S.

    2016-01-01

    Deficiency in complement component C1q is associated with an inability to clear apoptotic cells (efferocytosis) and aberrant inflammation in lupus, and identification of the pathways involved in these processes should reveal important regulatory mechanisms in lupus and other autoimmune or inflammatory diseases. In this study, C1q-dependent regulation of TNFα/IL-6 expression and efferocytosis was investigated using primary mouse bone marrow-derived macrophages and human monocyte-derived macrophages. C1q downregulated LPS-dependent TNFα production in mouse and human macrophages. While prolonged stimulation with C1q (18 h) was required to elicit a dampening of TNFα production from mouse macrophages, the human macrophages responded to C1q with immediate downregulation of TNFα. IL-6 production was unchanged in mouse and upregulated by human macrophages following prolonged stimulation with C1q. Our previous studies indicated that C1q programmed enhanced efferocytosis in mouse macrophages by enhancing expression of Mer tyrosine kinase and its ligand Gas6, a receptor–ligand pair that also inhibits proinflammatory signaling. Here, we demonstrated that C1q-dependent programming of human macrophage efferocytosis required protein synthesis; however, neither Mer nor the related receptor Axl was upregulated in human cells. In addition, while the C1q-collagen-like tails are sufficient for promoting C1q-dependent phagocytosis of antibody-coated targets, the C1q-tails failed to program enhanced efferocytosis or dampen TNFα production. These data further elucidate the mechanisms by which C1q regulates proinflammatory signaling and efferocytosis in macrophages, functions that are likely to influence the progression of autoimmunity and chronic inflammation. PMID:27379094

  15. 40 CFR 265.19 - Construction quality assurance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Construction quality assurance program..., STORAGE, AND DISPOSAL FACILITIES General Facility Standards § 265.19 Construction quality assurance program. (a) CQA program. (1) A construction quality assurance (CQA) program is required for all...

  16. 40 CFR 264.19 - Construction quality assurance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Construction quality assurance program... FACILITIES General Facility Standards § 264.19 Construction quality assurance program. (a) CQA program. (1) A construction quality assurance (CQA) program is required for all surface impoundment, waste pile, and...

  17. Flexible Language Constructs for Large Parallel Programs

    DOE PAGESBeta

    Rosing, Matt; Schnabel, Robert

    1994-01-01

    The goal of the research described in this article is to develop flexible language constructs for writing large data parallel numerical programs for distributed memory (multiple instruction multiple data [MIMD]) multiprocessors. Previously, several models have been developed to support synchronization and communication. Models for global synchronization include single instruction multiple data (SIMD), single program multiple data (SPMD), and sequential programs annotated with data distribution statements. The two primary models for communication include implicit communication based on shared memory and explicit communication based on messages. None of these models by themselves seem sufficient to permit the natural and efficient expression ofmore » the variety of algorithms that occur in large scientific computations. In this article, we give an overview of a new language that combines many of these programming models in a clean manner. This is done in a modular fashion such that different models can be combined to support large programs. Within a module, the selection of a model depends on the algorithm and its efficiency requirements. In this article, we give an overview of the language and discuss some of the critical implementation details.« less

  18. Flexible language constructs for large parallel programs

    NASA Technical Reports Server (NTRS)

    Rosing, Matthew; Schnabel, Robert

    1993-01-01

    The goal of the research described is to develop flexible language constructs for writing large data parallel numerical programs for distributed memory (MIMD) multiprocessors. Previously, several models have been developed to support synchronization and communication. Models for global synchronization include SIMD (Single Instruction Multiple Data), SPMD (Single Program Multiple Data), and sequential programs annotated with data distribution statements. The two primary models for communication include implicit communication based on shared memory and explicit communication based on messages. None of these models by themselves seem sufficient to permit the natural and efficient expression of the variety of algorithms that occur in large scientific computations. An overview of a new language that combines many of these programming models in a clean manner is given. This is done in a modular fashion such that different models can be combined to support large programs. Within a module, the selection of a model depends on the algorithm and its efficiency requirements. An overview of the language and discussion of some of the critical implementation details is given.

  19. 78 FR 4157 - Manufactured Home Construction and Safety Standards Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Manufactured Home Construction and Safety Standards Program AGENCY: Office of the... information: Title of Proposal: Manufactured Home Construction and Safety Standards Program. OMB...

  20. Epigenetic Regulation of Placental "NR3C1": Mechanism Underlying Prenatal Programming of Infant Neurobehavior by Maternal Smoking?

    ERIC Educational Resources Information Center

    Stroud, Laura R.; Papandonatos, George D.; Salisbury, Amy L.; Phipps, Maureen G.; Huestis, Marilyn A.; Niaura, Raymond; Padbury, James F.; Marsit, Carmen J.; Lester, Barry M.

    2016-01-01

    Epigenetic regulation of the placental glucocorticoid receptor gene ("NR3C1") was investigated as a mechanism underlying links between maternal smoking during pregnancy (MSDP) and infant neurobehavior in 45 mother-infant pairs (49% MSDP-exposed; 52% minorities; ages 18-35). The Neonatal Intensive Care Unit (NICU) Network Neurobehavioral…

  1. Construction safety program for the National Ignition Facility

    SciTech Connect

    Cerruti, S.J.

    1997-06-26

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and initial activation and operation of NIF at LLNL during the construction period of NIF.

  2. Local School Construction Programs. Bulletin, 1957, No. 20

    ERIC Educational Resources Information Center

    Viles, N. E.

    1957-01-01

    This bulletin is designed as an outline to direct the attention of local officials to various features and steps meriting attention in planning and carrying out a school-plant construction program. Planning, administration, and construction practices and procedures may vary with buildings of different sizes or types of construction or with those…

  3. Internal Construct Validity of the Career Skills Assessment Program.

    ERIC Educational Resources Information Center

    Rock, Donald A.

    The primary purpose of this study was to provide evidence for or against the construct validity of the Career Skills Assessment Program (CSAP) instrument. A secondary purpose was to present a systematic procedure for carrying out internal construct validity studies in any testing instrument. Construct validation using confirmatory factor analysis…

  4. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Summary of construction grant program. 35.903 Section 35.903 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.903 Summary of construction grant...

  5. Construction safety program for the National Ignition Facility

    SciTech Connect

    Cerruti, S.J.

    1997-01-01

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and initial activation and operation of NIF at LLNL during the construction period of NIF. During this period, all workers are required to implement measures to create a universal awareness which promotes safe practice at the work site, and which will achieve NIF`s management objectives in preventing accidents and illnesses. Construction safety for NIF is predicated on everyone performing their jobs in a manner which prevents job-related disabling injuries and illnesses. The CSP outlines the minimum environment, safety, and health (ES&H) standards, LLNL policies and the Construction Industry Institute (CII) Zero Injury Techniques requirements that all workers at the NIF construction site shall adhere to during the construction period of NIF. It identifies the safety requirements which the NIF organizational Elements, construction contractors and construction subcontractors must include in their safety plans for the construction period of NIF, and presents safety protocols and guidelines which workers shall follow to assure a safe and healthful work environment. The CSP also identifies the ES&H responsibilities of LLNL employees, non-LLNL employees, construction contractors, construction subcontractors, and various levels of management within the NIF Program at LLNL. In addition, the CSP contains the responsibilities and functions of ES&H support organizations and administrative groups, and describes their interactions with the NIF Program.

  6. 42 CFR 137.275 - May Self-Governance Tribes include IHS construction programs in a construction project agreement...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... programs in a construction project agreement or in a funding agreement? 137.275 Section 137.275 Public...-Governance Tribes include IHS construction programs in a construction project agreement or in a funding agreement? Yes, Self-Governance Tribes may choose to assume construction programs in a construction...

  7. Construction Pre-Apprenticeship Programs: Results from a National Survey

    ERIC Educational Resources Information Center

    Conway, Maureen; Gerber, Allison

    2009-01-01

    This publication shares findings from a WSI-conducted survey of pre-apprenticeship programs in the construction trades. Based on responses from 260 programs nationwide, the report presents information about program size, services offered, populations served, funding sources, and successes and challenges in placing trainees in apprenticeships or…

  8. Constructing Effective Corporate Adventure Training Programs.

    ERIC Educational Resources Information Center

    Gass, Michael; And Others

    1992-01-01

    Effective corporate adventure training programs: (1) develop parallel structures between the adventure experience and the workplace (context); (2) consider how the learning will address a company's future needs (continuity); (3) provide learners with valid information and feedback on their actions (consequences); and (4) create physically and…

  9. Public School Construction Program. Administrative Procedures Guide. Revised.

    ERIC Educational Resources Information Center

    Maryland State Interagency Committee on School Construction, Baltimore.

    The State of Maryland has published this guide that provides State and local personnel, architects, and governmental officials with the method of operation and administration of the State's Public School Construction Program. The material is arranged in sequential order and follows a project from inception through design, construction, and…

  10. Guidelines for Implementing State Skill Standards Certificate Program in Construction.

    ERIC Educational Resources Information Center

    Wisconsin State Dept. of Workforce Development, Madison.

    This packet contains guidelines, a student competency checklist, and student evaluation sheet for use in a Wisconsin school-to-work state skill standards certificate program in construction. The guidelines provide a planning resource for implementing the program, which was created in partnership with unions, employers, the state Department of…

  11. Annual Program: Library Services and Construction Act, 1987-1988.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    This report presents the 1978-1988 annual Library Services and Construction Act (LSCA) program for the South Carolina State Library. This program includes fiscal information and project descriptions for the following LCSA projects under Title I-Library Services: (1) Projects IA-General Administration; (2) IB-Library Interpretation; (3) IIA-General…

  12. Annual Program. Library Services and Construction Act, 1988-1989.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    This report presents the 1988-1989 annual Library Services and Construction Act (LSCA) program for the South Carolina State Library. This program includes fiscal information and project descriptions for the following LSCA projects under Title I Library Services: (1) I-A, General Administration; (2) I-B, Library Interpretation; (3) II-A, General…

  13. The NIOSH Construction Program: research to practice, impact, and developing a National Construction Agenda.

    PubMed

    Gillen, Matt

    2010-06-01

    The U.S. National Institute for Occupational Safety and Health (NIOSH) conducts research to improve and protect the health and safety of workers. This paper describes the experience of the NIOSH Construction Program with two recent program planning initiatives intended to improve the program: (a) an independent external review of work over the past decade and (b) the development of strategic goals organized into a "National Construction Agenda" to guide a decade of future work. These goals, developed with input from construction industry stakeholders and researchers, are a part of the NIOSH National Occupational Research Agenda (NORA) initiative. The NORA goals are intended to provide an ambitious set of goals for all construction stakeholders to work together on. Both efforts relate to insuring the relevance and impact of research, reflecting an emerging policy perspective that research programs should be judged not just by the quality and quantity of science produced, but by the industry impact and tangible benefit resulting from the research. This paper describes how views on research planning have evolved to incorporate lessons learned about how research leads to improved safety and health for workers. It also describes the process used to develop the goals and the resulting strategic and intermediate goals that comprise the National Construction Agenda. PMID:20630280

  14. Development of a safety communication and recognition program for construction.

    PubMed

    Sparer, Emily H; Herrick, Robert F; Dennerlein, Jack T

    2015-05-01

    Leading-indicator-based (e.g., hazard recognition) incentive programs provide an alternative to controversial lagging-indicator-based (e.g., injury rates) programs. We designed a leading-indicator-based safety communication and recognition program that incentivized safe working conditions. The program was piloted for two months on a commercial construction worksite and then redesigned using qualitative interview and focus group data from management and workers. We then ran the redesigned program for six months on the same worksite. Foremen received detailed weekly feedback from safety inspections, and posters displayed worksite and subcontractor safety scores. In the final program design, the whole site, not individual subcontractors, was the unit of analysis and recognition. This received high levels of acceptance from workers, who noted increased levels of site unity and team-building. This pilot program showed that construction workers value solidarity with others on site, demonstrating the importance of health and safety programs that engage all workers through a reliable and consistent communication infrastructure. PMID:25815741

  15. Annual Program: Library Services and Construction Act 1990-1991.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    The 1990-1991 Library Services and Construction Act (LSCA) program is presented in this report for the South Carolina State Library. The document includes fiscal information and project descriptions for the following LSCA Title I projects: (1) General Administration; (2) Library Interpretation; (3) General Operations; (4) Strengthening the State…

  16. Annual Program: Library Services and Construction Act 1991-1992.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    The 1991-1992 Library Services and Construction Act (LSCA) program is presented in this report for the South Carolina State Library. The document includes fiscal information and project descriptions for the following LSCA Title I projects: (1) General Administration; (2) Library Interpretation; (3) General Operations; (4) Strengthening the State…

  17. Annual Program. Library Services and Construction Act, 1989-1990.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    The 1989-1990 Library Services and Construction Act (LSCA) program is presented in this report for the South Carolina State Library. The document includes fiscal information and project descriptions for the following LSCA Title I projects: (1) General Administration; (2) Library Interpretation; (3) General Operations; (4) Strengthening the State…

  18. 40 CFR 265.19 - Construction quality assurance program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Construction quality assurance program. 265.19 Section 265.19 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) INTERIM STATUS STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES General...

  19. 40 CFR 264.19 - Construction quality assurance program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Construction quality assurance program. 264.19 Section 264.19 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES General Facility Standards...

  20. Programmed Instruction: Construction Responding, Discrimination Responding, and Highlighted Keywords

    ERIC Educational Resources Information Center

    Miller, Matthew L.; Malott, Richard W.

    2006-01-01

    Skinner (1958) expressed the need for an increase in the effectiveness and efficiency of education. In particular, he suggested that programmed instruction could provide such efficiency. The present study used a within-subject design to compare the effects of four types of instructional materials; those requiring overt construction responses,…

  1. Language constructs and runtime systems for compositional parallel programming

    SciTech Connect

    Foster, I.; Kesselman, C.

    1995-03-01

    In task-parallel programs, diverse activities can take place concurrently, and communication and synchronization patterns are complex and not easily predictable. Previous work has identified compositionality as an important design principle for task-parallel programs. In this paper, we discuss alternative approaches to the realization of this principle. We first provide a review and critical analysis of Strand, an early compositional programming language. We examine the strengths of the Strand approach and also its weaknesses, which we attribute primarily to the use of a specialized language. Then, we present an alternative programming language framework that overcomes these weaknesses. This framework uses simple extensions to existing sequential languages (C++ and Fortran) and a common runtime system to provide a basis for the construction of large, task-parallel programs. We also discuss the runtime system techniques required to support these languages on parallel and distributed computer systems.

  2. 42 CFR 137.275 - May Self-Governance Tribes include IHS construction programs in a construction project agreement...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... services and construction management services. Construction Definitions ... 42 Public Health 1 2014-10-01 2014-10-01 false May Self-Governance Tribes include IHS construction programs in a construction project agreement or in a funding agreement? 137.275 Section 137.275...

  3. 42 CFR 137.275 - May Self-Governance Tribes include IHS construction programs in a construction project agreement...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... services and construction management services. Construction Definitions ... 42 Public Health 1 2013-10-01 2013-10-01 false May Self-Governance Tribes include IHS construction programs in a construction project agreement or in a funding agreement? 137.275 Section 137.275...

  4. 42 CFR 137.275 - May Self-Governance Tribes include IHS construction programs in a construction project agreement...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... services and construction management services. Construction Definitions ... 42 Public Health 1 2012-10-01 2012-10-01 false May Self-Governance Tribes include IHS construction programs in a construction project agreement or in a funding agreement? 137.275 Section 137.275...

  5. 42 CFR 137.275 - May Self-Governance Tribes include IHS construction programs in a construction project agreement...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false May Self-Governance Tribes include IHS construction... OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Purpose and Scope § 137.275 May Self-Governance Tribes include IHS construction programs in a construction project agreement or in a...

  6. 40 CFR 264.19 - Construction quality assurance program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... conductivity requirements of §§ 264.221(c)(1)(i)(B), 264.251(c)(1)(i)(B), and 264.301(c)(1)(i)(B) in the field. Compliance with the hydraulic conductivity requirements must be verified by using in-situ testing on the... conductivity requirements of §§ 264.221(c)(1)(i)(B), 264.251(c)(1)(i)(B), and 264.301(c)(1)(i)(B) in the...

  7. Automating construction through the use of robotics and Graphical Programming

    SciTech Connect

    McDonald, M.J.; Palmquist, R.D.

    1993-08-01

    Sandia has developed an advanced operational control system approach, called Graphical Programming, to design and operate robot systems in unstructured environments. This Graphical Programming approach produces robot systems that are faster to develop and use, safer in operation, and cheaper overall than altemative teleoperation or autonomous robot control systems. This approach uses 3-D visualization and simulation software with intuitive operator interfaces for the programming and control of complex robotic systems. Supervisor software modules allow an operator to command and simulate complex tasks in a graphic preview mode and, when acceptable, command the actual robots and monitor their motions with the graphic system. Graphical Programming Supervisors maintain registration with the real world and allow the robot to perform tasks that cannot be accurately represented with models alone by using a combination of model and sensor-based control. All of these capabilities when combined result in a flexible system which is readily able to meet the demands called for in construction automation. This paper describes the Graphical Programming approach, several example control systems that use Graphical Programming, key features necessary for implementing successful Graphical Programming systems, and specific examples of applying these systems to robotic operations.

  8. Duct Remediation Program: Engineered access research and construction

    SciTech Connect

    Beckman, T.D.; Davis, M.M.; Karas, T.M.

    1992-11-01

    The Rocky Flats Plant, Duct Remediation mission concentrated on removing Plutonium Oxide from the process ductwork in the primary Plutonium processing facility. When possible, remediation took place from existing process gloveboxes. Fifteen locations were identified, however, that required accessing duct runs where no process gloveboxes existed. The building`s second floor utility areas had many locations where long, inaccessible duct runs were prevalent. Consequently, an extensive program for design, procurement and construction was initiated to contain and isolate ducts for penetration when existing glovebox sites were not present.

  9. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Applicability. 52c.1 Section 52c.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public...

  10. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Applicability. 52c.1 Section 52c.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public...

  11. 77 FR 28573 - Applications for New Awards; Impact Aid Discretionary Construction Grant Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ... Applications for New Awards; Impact Aid Discretionary Construction Grant Program AGENCY: Office of Elementary and Secondary Education, Department of Education ACTION: Notice. Overview Information Impact Aid... Aid Discretionary Construction Grant program provides grants for emergency repairs and...

  12. 78 FR 13646 - Applications for New Awards; Impact Aid Discretionary Construction Grant Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... Applications for New Awards; Impact Aid Discretionary Construction Grant Program AGENCY: Office of Elementary and Secondary Education, Department of Education. ACTION: Notice. Overview Information Impact Aid... Impact Aid Discretionary Construction Grant program provides grants for emergency repairs...

  13. PHRQINPT, an interactive computer program for constructing input data sets to the geochemical simulation program PHREEQE

    USGS Publications Warehouse

    Fleming, G.W.; Plummer, L.N.

    1983-01-01

    PHRQINPT is a FORTRAN 77 program which facilitates formulation of the input data file to PHREEQE (Parkhurst, Thorstenson, and Plummer, 1980). PHRQINPT runs interactively and contains many features to help the user construct the input data set. This report describes these features and gives instructions on the use and implementation of PHRQINPT. A listing of the program and the two accompanying data sets are given in the attachments, along with two examples. (USGS)

  14. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Program; (b) Construction program functions; and, (c) Planning services and construction management... 42 Public Health 1 2011-10-01 2011-10-01 false Does this subpart cover construction programs? 137... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE...

  15. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Program; (b) Construction program functions; and, (c) Planning services and construction management... 42 Public Health 1 2014-10-01 2014-10-01 false Does this subpart cover construction programs? 137... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE...

  16. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Program; (b) Construction program functions; and, (c) Planning services and construction management... 42 Public Health 1 2012-10-01 2012-10-01 false Does this subpart cover construction programs? 137... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE...

  17. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Program; (b) Construction program functions; and, (c) Planning services and construction management... 42 Public Health 1 2013-10-01 2013-10-01 false Does this subpart cover construction programs? 137... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE...

  18. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Restoration Program construction contracts. 228.102-70 Section 228.102-70 Federal Acquisition Regulations... BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction contracts. For Defense Environmental Restoration Program construction contracts entered into pursuant to 10...

  19. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Restoration Program construction contracts. 228.102-70 Section 228.102-70 Federal Acquisition Regulations... BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction contracts. For Defense Environmental Restoration Program construction contracts entered into pursuant to 10...

  20. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Restoration Program construction contracts. 228.102-70 Section 228.102-70 Federal Acquisition Regulations... BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction contracts. For Defense Environmental Restoration Program construction contracts entered into pursuant to 10...

  1. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Restoration Program construction contracts. 228.102-70 Section 228.102-70 Federal Acquisition Regulations... BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction contracts. For Defense Environmental Restoration Program construction contracts entered into pursuant to 10...

  2. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Restoration Program construction contracts. 228.102-70 Section 228.102-70 Federal Acquisition Regulations... BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction contracts. For Defense Environmental Restoration Program construction contracts entered into pursuant to 10...

  3. Genetic programs constructed from layered logic gates in single cells

    PubMed Central

    Moon, Tae Seok; Lou, Chunbo; Tamsir, Alvin; Stanton, Brynne C.; Voigt, Christopher A.

    2014-01-01

    Genetic programs function to integrate environmental sensors, implement signal processing algorithms and control expression dynamics1. These programs consist of integrated genetic circuits that individually implement operations ranging from digital logic to dynamic circuits2–6, and they have been used in various cellular engineering applications, including the implementation of process control in metabolic networks and the coordination of spatial differentiation in artificial tissues. A key limitation is that the circuits are based on biochemical interactions occurring in the confined volume of the cell, so the size of programs has been limited to a few circuits1,7. Here we apply part mining and directed evolution to build a set of transcriptional AND gates in Escherichia coli. Each AND gate integrates two promoter inputs and controls one promoter output. This allows the gates to be layered by having the output promoter of an upstream circuit serve as the input promoter for a downstream circuit. Each gate consists of a transcription factor that requires a second chaperone protein to activate the output promoter. Multiple activator–chaperone pairs are identified from type III secretion pathways in different strains of bacteria. Directed evolution is applied to increase the dynamic range and orthogonality of the circuits. These gates are connected in different permutations to form programs, the largest of which is a 4-input AND gate that consists of 3 circuits that integrate 4 inducible systems, thus requiring 11 regulatory proteins. Measuring the performance of individual gates is sufficient to capture the behaviour of the complete program. Errors in the output due to delays (faults), a common problem for layered circuits, are not observed. This work demonstrates the successful layering of orthogonal logic gates, a design strategy that could enable the construction of large, integrated circuits in single cells. PMID:23041931

  4. Better Space Construction Decisions by Instructional Program Simulation Utilizing the Generalized Academic Simulation Programs.

    ERIC Educational Resources Information Center

    Apker, Wesley

    This school district utilized the generalized academic simulation programs (GASP) to assist in making decisions regarding the kinds of facilities that should be constructed at Pilchuck Senior High School. Modular scheduling was one of the basic educational parameters used in determining the number and type of facilities needed. The objectives of…

  5. Feasibility of home infusion and self-administration of nanofiltered C1 esterase inhibitor for routine prophylaxis in patients with hereditary angioedema and characterization of a training and support program.

    PubMed

    Gregory, Cherylann; Landmesser, Ladonna M; Corrigan, Larry; Mariano, David

    2014-01-01

    Hereditary angioedema (HAE) is a rare, chronic disease of C1 inhibitor deficiency. Study researchers evaluated the prevalence of home and self-administration of nanofiltered, human-derived C1 esterase inhibitor infusions and the implementation of a nursing training and support program. Home administration rate increased from 49.0% to 75.8%. The percentage who self-administered increased from 20.3% to 43.9%. Doses per week averaged 1.85 at home compared with 1.40 in infusion centers and physicians' offices. Patients required an average of 5 visits to be trained. Self-administration is a viable, feasible option in the management of HAE, which is facilitated by a nurse-managed training and support program. PMID:24384882

  6. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... specifications for the construction project, and where applicable, sufficient explanations of technical... for programs which include construction projects. 17.255 Section 17.255 Pensions, Bonuses, and... Applications for grants for programs which include construction projects. In addition to the documents...

  7. Extravehicular Crewman Work System (ECWS) study program. Volume 2: Construction

    NASA Technical Reports Server (NTRS)

    Wilde, R. C.

    1980-01-01

    The construction portion of the Extravehicular Crewman Work System Study defines the requirements and selects the concepts for the crewman work system required to support the construction of large structures in space.

  8. Corporate Mentors and Undergraduate Students: A Qualitative Study of the Advancing Women in Construction Mentorship Program

    ERIC Educational Resources Information Center

    Eicher, Matthew

    2013-01-01

    In a conscious effort to combat the low enrollment of women in construction management, a program was created to retain women through a mentorship program--Advancing Women in Construction. A qualitative analysis, facilitated through a grounded theory approach, sought to understand if the program was indeed successful, and what value did the…

  9. 1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells

    SciTech Connect

    Asare, Nana Landvik, Nina E.; Lagadic-Gossmann, Dominique; Rissel, Mary; Tekpli, Xavier; Ask, Kjetil; Lag, Marit; Holme, Jorn A.

    2008-07-15

    Mechanistic studies of nitro-PAHs (polycyclic aromatic hydrocarbons) of interest might help elucidate which chemical characteristics are most important in eliciting toxic effects. 1-Nitropyrene (1-NP) is the predominant nitrated PAH emitted in diesel exhaust. 1-NP-exposed Hepa1c1c7 cells exhibited marked changes in cellular morphology, decreased proliferation and different forms of cell death. A dramatic increase in cytoplasmic vacuolization was observed already after 6 h of exposure and the cells started to round up at 12 h. The rate of cell proliferation was markedly reduced at 24 h and apoptotic as well as propidium iodide (PI)-positive cells appeared. Electron microscopic examination revealed that the vacuolization was partly due to mitochondria swelling. The caspase inhibitor Z-VAD-FMK inhibited only the apoptotic cell death and Nec-1 (an inhibitor of necroptosis) exhibited no inhibitory effects on either cell death or vacuolization. In contrast, cycloheximide markedly reduced both the number of apoptotic and PI-positive cells as well as the cytoplasmic vacuolization, suggesting that 1-NP induced paraptotic cell death. All the MAPKs; ERK1/2, p38 and JNK, appear to be involved in the death process since marked activation was observed upon 1-NP exposure, and their inhibitors partly reduced the induced cell death. The ERK1/2 inhibitor PD 98057 completely blocked the induced vacuolization, whereas the other MAPKs inhibitors only had minor effects on this process. These findings suggest that 1-NP may cause apoptosis and paraptosis. In contrast, the corresponding amine (1-aminopyrene) elicited only minor apoptotic and necrotic cell death, and cells with characteristics typical of paraptosis were absent.

  10. 1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells.

    PubMed

    Asare, Nana; Landvik, Nina E; Lagadic-Gossmann, Dominique; Rissel, Mary; Tekpli, Xavier; Ask, Kjetil; Låg, Marit; Holme, Jørn A

    2008-07-15

    Mechanistic studies of nitro-PAHs (polycyclic aromatic hydrocarbons) of interest might help elucidate which chemical characteristics are most important in eliciting toxic effects. 1-Nitropyrene (1-NP) is the predominant nitrated PAH emitted in diesel exhaust. 1-NP-exposed Hepa1c1c7 cells exhibited marked changes in cellular morphology, decreased proliferation and different forms of cell death. A dramatic increase in cytoplasmic vacuolization was observed already after 6 h of exposure and the cells started to round up at 12 h. The rate of cell proliferation was markedly reduced at 24 h and apoptotic as well as propidium iodide (PI)-positive cells appeared. Electron microscopic examination revealed that the vacuolization was partly due to mitochondria swelling. The caspase inhibitor Z-VAD-FMK inhibited only the apoptotic cell death and Nec-1 (an inhibitor of necroptosis) exhibited no inhibitory effects on either cell death or vacuolization. In contrast, cycloheximide markedly reduced both the number of apoptotic and PI-positive cells as well as the cytoplasmic vacuolization, suggesting that 1-NP induced paraptotic cell death. All the MAPKs; ERK1/2, p38 and JNK, appear to be involved in the death process since marked activation was observed upon 1-NP exposure, and their inhibitors partly reduced the induced cell death. The ERK1/2 inhibitor PD 98057 completely blocked the induced vacuolization, whereas the other MAPKs inhibitors only had minor effects on this process. These findings suggest that 1-NP may cause apoptosis and paraptosis. In contrast, the corresponding amine (1-aminopyrene) elicited only minor apoptotic and necrotic cell death, and cells with characteristics typical of paraptosis were absent. PMID:18417179

  11. Constructing and Verifying Program Theory Using Source Documentation

    ERIC Educational Resources Information Center

    Renger, Ralph

    2010-01-01

    Making the program theory explicit is an essential first step in Theory Driven Evaluation (TDE). Once explicit, the program logic can be established making necessary links between the program theory, activities, and outcomes. Despite its importance evaluators often encounter situations where the program theory is not explicitly stated. Under such…

  12. 40 CFR 264.19 - Construction quality assurance program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Geomembranes (flexible membrane liners); (v) Leachate collection and removal systems and leak detection systems... section; (ii) Proper construction of all components of the liners, leachate collection and removal...

  13. Construction Management Guidelines for Capital Outlay Program Projects.

    ERIC Educational Resources Information Center

    Georgia State Dept. of Education, Atlanta. Facilities Services Unit.

    The Georgia State Department of Education recognizes two separate methods for utilizing construction management services by local school systems when state capital outlay funds are involved. This report details those two methods. The report first describes the Construction Management (CM)-Agency approach, which allows a CM-Agency manager to enter…

  14. Constructing a Conceptual Framework for Elementary Algebra through Logo Programming.

    ERIC Educational Resources Information Center

    Noss, Richard

    1986-01-01

    This study, part of a longitudinal investigation, examined the kinds of thinking which children aged 10 and 11 could carry over from Logo instruction to an algebraic context. Interviews focused on their ability to construct meaningful symbolization for the concept of variable and to construct formalized algebraic rules. (MNS)

  15. 75 FR 60263 - Federal Acquisition Regulation; Offering a Construction Requirement-8(a) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... Federal Acquisition Regulation; Offering a Construction Requirement--8(a) Program AGENCIES: Department of... submitting offering letters to SBA for a construction requirement for which a specific offeror is nominated... offerings for construction ] requirements be submitted to the SBA District Office for the geographical...

  16. Adults' Perceptions of Knowledge Construction as Participants in Nonformal World Affairs Programs: An Interpretive Study

    ERIC Educational Resources Information Center

    Yelich Biniecki, Susan M.

    2015-01-01

    The purpose of this interpretive research study was to explore how adult learners perceive they construct knowledge in connection to their participation in nonformal world affairs programs. The study context involved the exploration of 12 adult learners' perceptions of their knowledge construction as participants in world affairs programs held in…

  17. A Solid Foundation: Key Capacities of Construction Pre-Apprenticeship Programs

    ERIC Educational Resources Information Center

    Helmer, Matt; Blair, Amy; Gerber, Allison

    2012-01-01

    This publication shares research from site visits conducted to construction pre-apprenticeship programs in Baltimore, Hartford, Milwaukee and Portland (OR). Findings from the site visits, which included interviews and focus groups with pre-apprenticeship program staff, public officials, philanthropic leaders, construction industry leaders and…

  18. New Tactics for Building: Experience/Analysis/Recommendations from the Detroit Public Schools Construction Systems Program.

    ERIC Educational Resources Information Center

    Cleland, Wallace B., Ed.

    This study is focused on organizational and procedural aspects of the Construction Systems Program (CSP), a developmental/demonstration project. The report is derived principally from practical observations by 42 active participants (architects, engineers, contractors, construction managers, owner's staff) in a four-school pilot program. Also…

  19. 78 FR 25062 - Program for Construction, Renovation, Repair or Expansion of Public Schools Located on Military...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-29

    ... of the Secretary Program for Construction, Renovation, Repair or Expansion of Public Schools Located... program to construct, renovate, repair, or expand elementary and ] secondary public schools on military... and secondary public schools on military installations in order to address capacity or...

  20. 7 CFR 15e.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false Program accessibility: New construction and... AGRICULTURE § 15e.151 Program accessibility: New construction and alterations. Each building or part of a... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section....

  1. 7 CFR 15e.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Program accessibility: New construction and... AGRICULTURE § 15e.151 Program accessibility: New construction and alterations. Each building or part of a... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section....

  2. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act... requirement for public participation applies to the development of the State water pollution control...

  3. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act... requirement for public participation applies to the development of the State water pollution control...

  4. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act... requirement for public participation applies to the development of the State water pollution control...

  5. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act... requirement for public participation applies to the development of the State water pollution control...

  6. Labor productivity in heavy construction: impact on synfuels program employment

    SciTech Connect

    Kusterer, K.C.

    1980-06-01

    This study focuses on variations in labor productivity in the heavy construction industry. Productivity is one of a number of factors likely to affect the speed and cost of constructing a synthetic fuels plant. The findings of this study are presented with reference to synthetic fuels plants, but they are relevant to other large energy facilities as well. The data were gathered through a detailed literature search and extensive in-depth interviews with consultants in heavy industrial construction, union officials, and management. In this manner the most important determinants of labor productivity were identified and ranked in terms of relative significance. The type of project under construction is the most important factor affecting the productivity of heavy construction labor. Projects characterized by the utility work syndrome are large, complex, relatively unique, highly regulated, and have cost-plus contracts and tight deadlines. Such projects generally have lower-than-average levels of labor productivity. Labor productivity is also lowered by worker and management morale problems, due to delays and design changes, and by high levels of unemployment among construction workers. Finally, boom town conditions, caused by workers moving to live near large projects located in rural areas, also are likely to result in below-average labor productivity.Synthetic fuels plants are likely to have a number of these identified characteristics. Consequently, the findings suggest that labor productivity may well be a problem for the timely development of an economically competitive synthetic fuels industry.

  7. An Approach to Effortless Construction of Program Animations

    ERIC Educational Resources Information Center

    Velazquez-Iturbide, J. Angel; Pareja-Flores, Cristobal; Urquiza-Fuentes, Jaime

    2008-01-01

    Program animation systems have not been as widely adopted by computer science educators as we might expect from the firm belief that they can help in enhancing computer science education. One of the most notable obstacles to their adoption is the considerable effort that the production of program animations represents for the instructor. We…

  8. Characterizing Building Construction Decision Processes to Enhance DOE Program Design

    SciTech Connect

    Hostick, Donna J.; Slavich, Antoinette L.; Larson, Lars E.; Hostick, Cody J.; Skumanich, Marina; Crawford, Marjorie A.; Weber, Tami M.

    2003-10-01

    There is an established process for the design and construction of buildings. While the particulars will vary greatly from one project to the next, the players (e.g., architects, owners, supplies, builders) and activities (e.g., design, specify, construct) are basically the same, as are the decisions (e.g., which windows where, what type of heating system). The U.S. Department of Energy's (DOEs) Office of Energy Efficiency and Renewable Energy (EERE) tasked Pacific Northwest National Laboratory (PNNL) with the development of a formal framework that could be used to analyze the critical decision path for energy efficient technologies in the construction of buildings. The goal was to demonstrate whether these technologies could be related to decision points in the construction process, the decision makers, and a rudimentary understanding of what helped to form those decisions. The theory to be tested is whether this Critical Path Analysis can enhance project planning and design. A continuous goal of EERE is to increase the effectiveness of its efforts through better targeting of projects. This requires a good understanding of the markets in which EERE technologies and practices, as developed or implemented by those projects, must compete. One significant measure of project success is market adoption of EERE technologies and practices. The goal of this study is to characterize the typical design, construction, and building renovation decision points and decision makers to see if this information could prove useful to DOE Project Managers by helping them understand how market adoption decisions are made. The approach of this study is to develop a framework characterizing decision points, decision makers, and decision influences in the building industry. As many building design and construction decisions are time-sequenced and constrained by earlier decisions, the framework selected is based on a critical path characterization of the design and construction process

  9. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What is the Secretary's role in a construction program in... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.249 What is the Secretary's role in a construction program in an AFA? The Secretary has the following role regarding a construction program...

  10. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What is the Secretary's role in a construction program in... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.249 What is the Secretary's role in a construction program in an AFA? The Secretary has the following role regarding a construction program...

  11. Annual Program: Library Services and Construction Act. 1995-1996.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    This report provides information on South Carolina's Library Services and Construction Act (LSCA) projects for fiscal year 1995. It includes: copies of applications for federal assistance and grant award notifications; a list of LSCA staff and responsibilities; a fiscal breakdown for Titles I and III that itemizes spending on activities within…

  12. Annual Program: Library Services and Construction Act. 1994-1995.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    This report provides information on South Carolina's Library Services and Construction Act (LSCA) projects for fiscal year 1994. It includes: copies of applications for federal assistance and grant award notifications; a list of LSCA staff and responsibilities; a fiscal breakdown for Titles I and III that itemizes spending on activities within…

  13. Annual Program: Library Services and Construction Act. 1996-1997.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    This report provides information on South Carolina's Library Services and Construction Act (LSCA) projects for fiscal year 1996. It includes: copies of applications for federal assistance and grant award notifications; a list of LSCA staff and responsibilities; a fiscal breakdown for Titles I and III that itemizes spending on activities within…

  14. "It's All Up to You": How Welfare-to-Work Educational Programs Construct Workforce Success

    ERIC Educational Resources Information Center

    Sandlin, Jennifer A.

    2004-01-01

    This article discusses how two welfare education programs construct workforce success. Discourse about success in these programs falls into two basic camps: an individual-based self-motivation perspective and an external, structural, socioeconomic perspective. Although the individualistic perspective adhered to by the programs came into conflict…

  15. Financial Awareness Education with Apprentices in the Australian Construction Industry: Program Evaluation

    ERIC Educational Resources Information Center

    Du Plessis, Karin; Green, Emma

    2013-01-01

    A financial awareness education program was implemented with construction industry apprentices in Victoria, Australia. The program included face-to-face delivery of education around a range of financial management issues that apprentices face as they begin their apprenticeship. The paper reports on an evaluation of the program, which included…

  16. Multi-Objective Genetic Programming with Redundancy-Regulations for Automatic Construction of Image Feature Extractors

    NASA Astrophysics Data System (ADS)

    Watchareeruetai, Ukrit; Matsumoto, Tetsuya; Takeuchi, Yoshinori; Kudo, Hiroaki; Ohnishi, Noboru

    We propose a new multi-objective genetic programming (MOGP) for automatic construction of image feature extraction programs (FEPs). The proposed method was originated from a well known multi-objective evolutionary algorithm (MOEA), i.e., NSGA-II. The key differences are that redundancy-regulation mechanisms are applied in three main processes of the MOGP, i.e., population truncation, sampling, and offspring generation, to improve population diversity as well as convergence rate. Experimental results indicate that the proposed MOGP-based FEP construction system outperforms the two conventional MOEAs (i.e., NSGA-II and SPEA2) for a test problem. Moreover, we compared the programs constructed by the proposed MOGP with four human-designed object recognition programs. The results show that the constructed programs are better than two human-designed methods and are comparable with the other two human-designed methods for the test problem.

  17. Utility residential new construction programs: Going beyond the code. A report from the Database on Energy Efficiency Programs (DEEP) Project

    SciTech Connect

    Vine, E.

    1995-08-01

    Based on an evaluation of 10 residential new construction programs, primarily sponsored by investor-owned utilities in the United States, we find that many of these programs are in dire straits and are in danger of being discontinued because current inclusion of only direct program effects leads to the conclusion that they are not cost-effective. We believe that the cost-effectiveness of residential new construction programs can be improved by: (1) promoting technologies and advanced building design practices that significantly exceed state and federal standards; (2) reducing program marketing costs and developing more effective marketing strategies; (3) recognizing the role of these programs in increasing compliance with existing state building codes; and (4) allowing utilities to obtain an ``energy-savings credit`` from utility regulators for program spillover (market transformation) impacts. Utilities can also leverage their resources in seizing these opportunities by forming strong and trusting partnerships with the building community and with local and state government.

  18. Algorithm for constructing the programmed motion of a bounding vehicle for the flight phase

    NASA Technical Reports Server (NTRS)

    Lapshin, V. V.

    1979-01-01

    The construction of the programmed motion of a multileg bounding vehicle in the flight was studied. An algorithm is given for solving the boundary value problem for constructing this programmed motion. If the motion is shown to be symmetrical, a simplified use of the algorithm can be applied. A method is proposed for nonimpact of the legs during lift-off of the vehicle, and for softness at touchdown. Tables are utilized to construct this programmed motion over a broad set of standard motion conditions.

  19. Continuing medical education, needs assessment, and program development: theoretical constructs.

    PubMed

    Aherne, M; Lamble, W; Davis, P

    2001-01-01

    Continuing medical education (CME) program development and needs assessment have historically been practiced within the tradition of Ralph Tyler's education model. In light of transformational social, political, economic, and technical forces that demand greater account-ability and responsiveness from physicians, CME units are challenged to transform their cultures and structures from models that deliver education to models that support the facilitation of learning for enhanced competence and performance. This article describes key change forces for physicians and brings program development and needs assessment into focus for the discussion. The impact of change forces on program development and needs assessment are examined, and some techniques to move beyond the traditional approach of felt needs are presented as a way of enabling strategic administrative planning and change management. PMID:11291588

  20. Construction Management Program Builds Financial Development from the Ground up

    ERIC Educational Resources Information Center

    Nobe, Michael D.; Shuler, Scott; Grosse, Larry

    2007-01-01

    Recent economic and legislative changes have hit higher education hard and threaten the financial viability of many educational programs nationwide. With state support dwindling to less than 10 percent in some cases, institutions across the nation face a financial crisis. Many strategies have been explored and implemented, from campaigns to…

  1. Construction safety program for the National Ignition Facility, Appendix B

    SciTech Connect

    Cerruti, S.J.

    1997-06-26

    This Appendix contains material from the LLNL Health and Safety Manual as listed below. For sections not included in this list, please refer to the Manual itself. The areas covered are: asbestos, lead, fire prevention, lockout, and tag program confined space traffic safety.

  2. 40 CFR 264.19 - Construction quality assurance program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... components, where applicable: (i) Foundations; (ii) Dikes; (iii) Low-permeability soil liners; (iv..., leak detection system, and final cover system, according to permit specifications and good engineering... 264.301. (2) The CQA program shall include test fills for compacted soil liners, using the...

  3. Constructing a conflict resolution program for health care.

    PubMed

    Porter-O'Grady, Tim

    2004-01-01

    Resolving conflict throughout organizations requires a programmatic infrastructure and a committed management team. Leaders must recognize the need to approach conflict by building a format for learning, creating and managing an effective conflict management program. Careful attention to the elements of design and the stages of development can make all the difference in building a sustainable and useful conflict management approach. PMID:15600105

  4. Construction safety program for the National Ignition Facility, Appendix A

    SciTech Connect

    Cerruti, S.J.

    1997-06-26

    Topics covered in this appendix include: General Rules-Code of Safe Practices; 2. Personal Protective Equipment; Hazardous Material Control; Traffic Control; Fire Prevention; Sanitation and First Aid; Confined Space Safety Requirements; Ladders and Stairways; Scaffolding and Lift Safety; Machinery, Vehicles, and Heavy Equipment; Welding and Cutting-General; Arc Welding; Oxygen/Acetylene Welding and Cutting; Excavation, Trenching, and Shoring; Fall Protection; Steel Erection; Working With Asbestos; Radiation Safety; Hand Tools; Electrical Safety; Nonelectrical Work Performed Near Exposed High-Voltage Power-Distribution Equipment; Lockout/Tagout Requirements; Rigging; A-Cranes; Housekeeping; Material Handling and Storage; Lead; Concrete and Masonry Construction.

  5. Construction: Carpentry Concentration. Program CIP: 46.0000 Construction: Carpentry Concentration

    ERIC Educational Resources Information Center

    Agee, Kelly, Ed.

    2008-01-01

    Secondary vocational-technical education programs in Mississippi are faced with many challenges resulting from sweeping educational reforms at the national and state levels. Schools and teachers are increasingly being held accountable for providing true learning activities to every student in the classroom. This accountability is measured through…

  6. 11 CFR 9420.6 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE U.S. ELECTION ASSISTANCE COMMISSION § 9420..., constructed, or altered so as to be readily accessible to and usable by handicapped persons. The...

  7. 42 CFR 137.274 - Does this subpart cover construction programs?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Does this subpart cover construction programs? 137.274 Section 137.274 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Purpose and Scope § 137.274 Does this subpart...

  8. RECOMMENDED FOUNDATION FILL MATERIALS CONSTRUCTION STANDARD OF THE FLORIDA RADON RESEARCH PROGRAM

    EPA Science Inventory

    The report summarizes the technical basis for a recommended foundation fill materials standard for new construction houses in Florida. he radon-control construction standard was developed by the Florida Radon Research Program (FRRP). ill material standards are formulated for: (1)...

  9. Annual Program. Library Services and Construction Act, 1986-1987, and FY 1986 Summary.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    This document comprises the Library Services and Construction Act (LSCA) 1986-1987 annual program and the FY 86 LSCA summary for the South Carolina State Library. The annual program includes fiscal information and project descriptions for the following LSCA projects: (1) Title I--Library Services, including Projects IA--General Administration,…

  10. 10 CFR 4.551 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Program accessibility: New construction and alterations. 4.551 Section 4.551 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE COMMISSION Enforcement of Nondiscrimination on the Basis of Disability in...

  11. Constructing a Self-Funded Program Takes More than Just Dollars and Cents

    ERIC Educational Resources Information Center

    Burke, Scott

    2012-01-01

    With a little ingenuity and a lot of dedication, the author created a self-funded construction program that is weathering the ups and downs of school funding; it enjoys great support from the community, is accomplishing more with less, and collaborative efforts between teachers are paying off. Creating such a program takes time, vision,…

  12. 45 CFR 606.52 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... SCIENCE FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL SCIENCE FOUNDATION § 606.52 Program accessibility: New construction...

  13. 45 CFR 606.52 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... SCIENCE FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL SCIENCE FOUNDATION § 606.52 Program accessibility: New construction...

  14. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Barriers Act of 1968 (42 U.S.C. 4151-4175), as established in 41 CFR 101-19.600 to 101-19-607, apply to... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  15. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Barriers Act of 1968 (42 U.S.C. 4151-4175), as established in 41 CFR 101-19.600 to 101-19-607, apply to... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  16. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Barriers Act of 1968 (42 U.S.C. 4151-4175), as established in 41 CFR 101-19.600 to 101-19-607, apply to... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  17. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Barriers Act of 1968 (42 U.S.C. 4151-4175), as established in 41 CFR 101-19.600 to 101-19-607, apply to... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  18. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Barriers Act of 1968 (42 U.S.C. 4151-4175), as established in 41 CFR 101-19.600 to 101-19-607, apply to... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  19. 45 CFR 606.52 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... SCIENCE FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL SCIENCE FOUNDATION § 606.52 Program accessibility: New construction...

  20. 45 CFR 606.52 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... SCIENCE FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL SCIENCE FOUNDATION § 606.52 Program accessibility: New construction...

  1. 45 CFR 606.52 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... SCIENCE FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL SCIENCE FOUNDATION § 606.52 Program accessibility: New construction...

  2. Creswell's Energy Efficient Construction Program: A Big Project for a Small School.

    ERIC Educational Resources Information Center

    Kelsh, Bruce

    1982-01-01

    In Creswell (Oregon) High School's award winning vocational education program, students study energy efficient construction along with basic building skills. Part of the program has been the active recruitment of female, minority, disadvantaged, and handicapped students into the vocational area. Students have assembled solar hot water collectors,…

  3. Item Pool Construction Using Mixed Integer Quadratic Programming (MIQP). GMAC® Research Report RR-14-01

    ERIC Educational Resources Information Center

    Han, Kyung T.; Rudner, Lawrence M.

    2014-01-01

    This study uses mixed integer quadratic programming (MIQP) to construct multiple highly equivalent item pools simultaneously, and compares the results from mixed integer programming (MIP). Three different MIP/MIQP models were implemented and evaluated using real CAT item pool data with 23 different content areas and a goal of equal information…

  4. Highway Safety Program Manual: Volume 12: Highway Design, Construction and Maintenance.

    ERIC Educational Resources Information Center

    National Highway Traffic Safety Administration (DOT), Washington, DC.

    Volume 12 of the 19-volume Highway Safety Program Manual (which provides guidance to State and local governments on preferred highway safety practices) focuses on highway design, construction and maintenance. The purpose and specific objectives of such a program are described. Federal authority in the area of highway safety and policies regarding…

  5. 45 CFR 2104.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this...) COMMISSION OF FINE ARTS ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE COMMISSION OF FINE ARTS § 2104.151 Program accessibility: New construction and...

  6. 29 CFR 1615.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Program accessibility: New construction and alterations. 1615.151 Section 1615.151 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE EQUAL EMPLOYMENT...

  7. 18 CFR 1313.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... TENNESSEE VALLEY AUTHORITY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE TENNESSEE VALLEY AUTHORITY § 1313.151 Program accessibility: New construction...

  8. MATES in Construction: Impact of a Multimodal, Community-Based Program for Suicide Prevention in the Construction Industry

    PubMed Central

    Gullestrup, Jorgen; Lequertier, Belinda; Martin, Graham

    2011-01-01

    A large-scale workplace-based suicide prevention and early intervention program was delivered to over 9,000 construction workers on building sites across Queensland. Intervention components included universal General Awareness Training (GAT; general mental health with a focus on suicide prevention); gatekeeper training provided to construction worker volunteer ‘Connectors’; Suicide First Aid (ASIST) training offered to key workers; outreach support provided by trained and supervised MIC staff; state-wide suicide prevention hotline; case management service; and postvention support provided in the event of a suicide. Findings from over 7,000 workers (April 2008 to November 2010) are reported, indicating strong construction industry support, with 67% building sites and employers approached agreeing to participate in MIC. GAT participants demonstrated significantly increased suicide prevention awareness compared with a comparison group. Connector training participants rated MIC as helpful and effective, felt prepared to intervene with a suicidal person, and knew where to seek help for a suicidal individual following the training. Workers engaged positively with the after-hours crisis support phone line and case management. MIC provided postvention support to 10 non-MIC sites and sites engaged with MIC, but not yet MIC-compliant. Current findings support the potential effectiveness and social validity of MIC for preventing suicide in construction workers. PMID:22163201

  9. Accurate construction of consensus genetic maps via integer linear programming.

    PubMed

    Wu, Yonghui; Close, Timothy J; Lonardi, Stefano

    2011-01-01

    We study the problem of merging genetic maps, when the individual genetic maps are given as directed acyclic graphs. The computational problem is to build a consensus map, which is a directed graph that includes and is consistent with all (or, the vast majority of) the markers in the input maps. However, when markers in the individual maps have ordering conflicts, the resulting consensus map will contain cycles. Here, we formulate the problem of resolving cycles in the context of a parsimonious paradigm that takes into account two types of errors that may be present in the input maps, namely, local reshuffles and global displacements. The resulting combinatorial optimization problem is, in turn, expressed as an integer linear program. A fast approximation algorithm is proposed, and an additional speedup heuristic is developed. Our algorithms were implemented in a software tool named MERGEMAP which is freely available for academic use. An extensive set of experiments shows that MERGEMAP consistently outperforms JOINMAP, which is the most popular tool currently available for this task, both in terms of accuracy and running time. MERGEMAP is available for download at http://www.cs.ucr.edu/~yonghui/mgmap.html. PMID:20479505

  10. COOPERATIVE RESEARCH IN C1 CHEMISTRY

    SciTech Connect

    Gerald P. Huffman

    2001-04-30

    Faculty and students from five universities (Kentucky, West Virginia, Utah, Pittsburgh and Auburn) are collaborating on a basic research program to develop novel C1 chemistry processes for the production of clean, high quality transportation fuel. An Industrial Advisory Board (IAB) with members from Chevron, Eastman Chemical, Energy International, Teir Associates, and the Department of Defense has been formed to provide practical guidance to the program. The program has two principal objectives. (1) Develop technology for conversion of C1 source materials (natural gas, synthesis gas, carbon dioxide and monoxide, and methanol) into clean, high efficiency transportation fuel. (2) Develop novel processes for producing hydrogen from natural gas and other hydrocarbons. Some of the principal accomplishments of the program in its first two years are: (1) The addition of acetylenic compounds in Fischer-Tropsch synthesis is found to produce significant amounts of oxygenated products in FT diesel fuels. Such oxygenated products should decrease particulate matter (PM) emissions. (2) Nanoscale, binary, Fe-based catalysts supported on alumina have been shown to have significant activity for the decomposition of methane into pure hydrogen and potentially valuable multi-walled carbon nanotubes. (3) Catalytic synthesis processes have been developed for synthesis of diethyl carbonate, higher ethers, and higher alcohols from C1 source materials. Testing of the effect of adding these oxygenates to diesel fuel on PM emissions has begun using a well-equipped small diesel engine test facility. (4) Supercritical fluid (SCF) FT synthesis has been conducted under SCF hexane using both Fe and Co catalysts. There is a marked effect on the hydrocarbon product distribution, with a shift to higher carbon number products. These and other results are summarized.

  11. 25 CFR 170.404 - What happens when a tribe uses its IRR Program construction funds for transportation planning?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... construction funds for transportation planning? 170.404 Section 170.404 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Planning, Design, and Construction... tribe uses its IRR Program construction funds for transportation planning? In order for IRR...

  12. Cooperative Research in C1 Chemistry

    SciTech Connect

    Gerald P. Huffman

    2000-10-27

    C1 chemistry refers to the conversion of simple carbon-containing materials that contain one carbon atom per molecule into valuable products. The feedstocks for C1 chemistry include natural gas, carbon dioxide, carbon monoxide, methanol and synthesis gas (a mixture of carbon monoxide and hydrogen). Synthesis gas, or syngas, is produced primarily by the reaction of natural gas, which is principally methane, with steam. It can also be produced by gasification of coal, petroleum coke, or biomass. The availability of syngas from coal gasification is expected to increase significantly in the future because of increasing development of integrated gasification combined cycle (IGCC) power generation. Because of the abundance of remote natural gas, the advent of IGCC, and environmental advantages, C1 chemistry is expected to become a major area of interest for the transportation fuel and chemical industries in the relatively near future. The CFFLS will therefore perform a valuable national service by providing science and engineering graduates that are trained in this important area. Syngas is the source of most hydrogen. Approximately 10 trillion standard cubic feet (SCF) of hydrogen are manufactured annually in the world. Most of this hydrogen is currently used for the production of ammonia and in a variety of refining and chemical operations. However, utilization of hydrogen in fuel cells is expected to grow significantly in the next century. Syngas is also the feedstock for all methanol and Fischer-Tropsch plants. Currently, world consumption of methanol is over 25 million tons per year. There are many methanol plants in the U.S. and throughout the world. Methanol and oxygenated transportation fuel products play a significant role in the CFFLS C1 program. Currently, the only commercial Fischer-Tropsch plants are overseas, principally in South Africa (SASOL). However, new plants are being built or planned for a number of locations. One possible location for future F

  13. Software for C1 interpolation

    NASA Technical Reports Server (NTRS)

    Lawson, C. L.

    1977-01-01

    The problem of mathematically defining a smooth surface, passing through a finite set of given points is studied. Literature relating to the problem is briefly reviewed. An algorithm is described that first constructs a triangular grid in the (x,y) domain, and first partial derivatives at the modal points are estimated. Interpolation in the triangular cells using a method that gives C sup.1 continuity overall is examined. Performance of software implementing the algorithm is discussed. Theoretical results are presented that provide valuable guidance in the development of algorithms for constructing triangular grids.

  14. State Plan for Library Programs Under Library Services and Construction Act as Amended.

    ERIC Educational Resources Information Center

    Hawaii State Dept. of Education, Honolulu. Office of Library Services.

    Hawaii's State Plan for Library Programs under the Library Services and Construction Act includes the following sections: (1.0) General Provisions; (1.1) State Agency (exhibits are: Executive Order No. 19, and the Constitution of the State of Hawaii); (1.2) Free Library Services; (1.3) Tables of Organization; (1.4) Personnel; (1.5) Custody of…

  15. 5 CFR 723.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Program accessibility: New construction and alterations. 723.151 Section 723.151 Administrative Personnel OFFICE OF PERSONNEL...

  16. Engineering Certification Program Self-Study Course, Construction Inspection - Part II. Engineering Management [Series].

    ERIC Educational Resources Information Center

    Owsley, Fran, Ed.

    This book is a part of a self-study sequence in an engineering certification program. This volume concerns inspection and quality control of concrete structures. Sections titles are Inspection and Quality Control of Concrete; General Guides for Concrete Work; Concrete Floor and Slab Construction; Concrete Formwork; Correct and Incorrect Methods of…

  17. 36 CFR 1208.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... construction and alterations. 1208.151 Section 1208.151 Parks, Forests, and Public Property NATIONAL ARCHIVES... PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL ARCHIVES AND RECORDS ADMINISTRATION § 1208.151...

  18. Library Services and Construction Act (LSCA). South Carolina State-Administration Annual Program, 1992-1993.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    Supporting documentation for the grant and use of Federal Library Services and Construction Act (LSCA) funds in South Carolina is presented in this annual program. Under Title I, Library Services, the bulk of the grant money is planned for the following projects: (1) general administration (Project I-A); (2) library interpretation (Project I-B);…

  19. 44 CFR 16.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Program accessibility: New construction and alterations. 16.151 Section 16.151 Emergency Management and Assistance FEDERAL EMERGENCY... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  20. 44 CFR 16.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Program accessibility: New construction and alterations. 16.151 Section 16.151 Emergency Management and Assistance FEDERAL EMERGENCY... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  1. 5 CFR 723.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Program accessibility: New construction and alterations. 723.151 Section 723.151 Administrative Personnel OFFICE OF PERSONNEL...

  2. 5 CFR 723.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Program accessibility: New construction and alterations. 723.151 Section 723.151 Administrative Personnel OFFICE OF PERSONNEL...

  3. 41 CFR 105-8.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Program accessibility: New construction and alterations. 105-8.151 Section 105-8.151 Public Contracts and Property Management... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section....

  4. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Program accessibility: New construction and alterations. 51-10.151 Section 51-10.151 Public Contracts and Property Management... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  5. 41 CFR 105-8.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Program accessibility: New construction and alterations. 105-8.151 Section 105-8.151 Public Contracts and Property Management... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section....

  6. 41 CFR 105-8.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Program accessibility: New construction and alterations. 105-8.151 Section 105-8.151 Public Contracts and Property Management... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section....

  7. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Program accessibility: New construction and alterations. 51-10.151 Section 51-10.151 Public Contracts and Property Management... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  8. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Program accessibility: New construction and alterations. 51-10.151 Section 51-10.151 Public Contracts and Property Management... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  9. 44 CFR 16.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Program accessibility: New construction and alterations. 16.151 Section 16.151 Emergency Management and Assistance FEDERAL EMERGENCY... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  10. 5 CFR 723.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Program accessibility: New construction and alterations. 723.151 Section 723.151 Administrative Personnel OFFICE OF PERSONNEL...

  11. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false Program accessibility: New construction and alterations. 51-10.151 Section 51-10.151 Public Contracts and Property Management... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  12. 44 CFR 16.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Program accessibility: New construction and alterations. 16.151 Section 16.151 Emergency Management and Assistance FEDERAL EMERGENCY... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  13. 41 CFR 105-8.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Program accessibility: New construction and alterations. 105-8.151 Section 105-8.151 Public Contracts and Property Management... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section....

  14. 44 CFR 16.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Program accessibility: New construction and alterations. 16.151 Section 16.151 Emergency Management and Assistance FEDERAL EMERGENCY... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  15. 5 CFR 723.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Program accessibility: New construction and alterations. 723.151 Section 723.151 Administrative Personnel OFFICE OF PERSONNEL...

  16. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true Program accessibility: New construction and alterations. 51-10.151 Section 51-10.151 Public Contracts and Property Management... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600...

  17. Environmental Assessment for the Construction and Operation of the Constellation Program A-3 Test Stand

    NASA Technical Reports Server (NTRS)

    Kennedy, Carolyn D.

    2007-01-01

    This document is an environmental assessment that examines the environmental impacts of a proposed plan to clear land and to construct a test stand for use in testing the J-2X rocket engine at simulated altitude conditions in support of NASA's Constellation Program.

  18. 45 CFR 1214.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... 45 Public Welfare 4 2014-10-01 2014-10-01 false Program accessibility: New construction and...) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP...

  19. 45 CFR 1214.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... 45 Public Welfare 4 2010-10-01 2010-10-01 false Program accessibility: New construction and...) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP...

  20. 45 CFR 1214.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... 45 Public Welfare 4 2012-10-01 2012-10-01 false Program accessibility: New construction and...) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP...

  1. 45 CFR 1214.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... 45 Public Welfare 4 2013-10-01 2013-10-01 false Program accessibility: New construction and...) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP...

  2. 45 CFR 1214.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings... 45 Public Welfare 4 2011-10-01 2011-10-01 false Program accessibility: New construction and...) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP...

  3. 10 CFR 1041.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Program accessibility: New construction and alterations. 1041.151 Section 1041.151 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) ENFORCEMENT OF..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  4. 10 CFR 4.551 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Program accessibility: New construction and alterations. 4.551 Section 4.551 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  5. 10 CFR 1041.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Program accessibility: New construction and alterations. 1041.151 Section 1041.151 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) ENFORCEMENT OF..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  6. 10 CFR 4.551 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Program accessibility: New construction and alterations. 4.551 Section 4.551 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  7. 10 CFR 1041.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Program accessibility: New construction and alterations. 1041.151 Section 1041.151 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) ENFORCEMENT OF..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  8. 10 CFR 1041.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Program accessibility: New construction and alterations. 1041.151 Section 1041.151 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) ENFORCEMENT OF..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  9. 10 CFR 4.551 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Program accessibility: New construction and alterations. 4.551 Section 4.551 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  10. 10 CFR 1041.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Program accessibility: New construction and alterations. 1041.151 Section 1041.151 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) ENFORCEMENT OF..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  11. 10 CFR 4.551 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Program accessibility: New construction and alterations. 4.551 Section 4.551 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  12. 6 CFR 15.51 - Program accessibility; new construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 through 101-19.607 apply to buildings... alterations. 15.51 Section 15.51 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY... DEPARTMENT OF HOMELAND SECURITY § 15.51 Program accessibility; new construction and alterations....

  13. The Laborers-AGC Construction Skills Training Program. Final Performance Report.

    ERIC Educational Resources Information Center

    Tippie, John L.; Rice, Eric

    Patterned after a previously successful Laborers-Associated General Contractors model named the Construction Skills Training Program, a demonstration project was implemented at five regional training centers. At least eight courses were created, combined, or revised. Four full-length audiovisual support pieces were completed. Three courses were…

  14. 11 CFR 6.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., constructed, or altered so as to be readily accessible to and usable by handicapped persons. The definitions, requirements, and standards of the Architectural Barriers Act, 42 U.S.C. 4151-4157, as established in 41 CFR... NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE FEDERAL ELECTION...

  15. 45 CFR 1803.8 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.... TRUMAN SCHOLARSHIP FOUNDATION NONDISCRIMINATION ON THE BASIS OF HANDICAP § 1803.8 Program accessibility... by, on behalf of, or for the use of the Foundation shall be designed, constructed, or altered so...

  16. 45 CFR 1803.8 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.... TRUMAN SCHOLARSHIP FOUNDATION NONDISCRIMINATION ON THE BASIS OF HANDICAP § 1803.8 Program accessibility... by, on behalf of, or for the use of the Foundation shall be designed, constructed, or altered so...

  17. 45 CFR 1803.8 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.... TRUMAN SCHOLARSHIP FOUNDATION NONDISCRIMINATION ON THE BASIS OF HANDICAP § 1803.8 Program accessibility... by, on behalf of, or for the use of the Foundation shall be designed, constructed, or altered so...

  18. 45 CFR 1803.8 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.... TRUMAN SCHOLARSHIP FOUNDATION NONDISCRIMINATION ON THE BASIS OF HANDICAP § 1803.8 Program accessibility... by, on behalf of, or for the use of the Foundation shall be designed, constructed, or altered so...

  19. 45 CFR 1803.8 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.... TRUMAN SCHOLARSHIP FOUNDATION NONDISCRIMINATION ON THE BASIS OF HANDICAP § 1803.8 Program accessibility... by, on behalf of, or for the use of the Foundation shall be designed, constructed, or altered so...

  20. Constructing Adult Literacies at a Local Literacy Tutor-Training Program

    ERIC Educational Resources Information Center

    Roderick, Ryan

    2013-01-01

    This study investigates how literacy was constructed at an adult literacy organization's volunteer tutor-training program. By drawing on qualitative analysis of training texts used during training, such as training evaluations, and data gathered from interviews with experienced tutors, it is possible to identify the assumptions about literacy…

  1. Planning Construction Projects: An Evaluation Report for the Occupational Exploration Program.

    ERIC Educational Resources Information Center

    Altschuld, James W.; Pritz, Sandra

    The evaluation report is one of seven produced for the Occupational Exploration Program (OEP), a series of simulated occupational experiences designed for junior high school students. Describing the pilot testing of the simulation dealing with construction, the report contains sections describing the simulation context, evaluation procedures,…

  2. A Scientist or Salesman? Identity Construction through Referent Honorifics on a Japanese Shopping Channel Program

    ERIC Educational Resources Information Center

    Cook, Haruko Minegishi

    2013-01-01

    This paper explores how referent honorifics contribute to identity construction on a Japanese TV shopping channel program. Drawing on Ochs' twostep model of indexicality (1993, 1996) and Agah's proposal (1993) that honorifics are not directly linked to social status but index a "relative position within events of discursive…

  3. The Sexual Assault Teach In Program: Building Constructive Campus-Wide Discussions to Inspire Change

    ERIC Educational Resources Information Center

    Katz, Jennifer; DuBois, Melinda

    2013-01-01

    To begin to address the problem of campus sexual assault, we conducted a Teach In, an educational forum used to explore complex social problems. All students, faculty, and staff at our small liberal arts college were invited to participate. This paper summarizes our Teach In program, goals, and methods. By engaging in constructive, informed…

  4. 16 CFR 1034.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Program accessibility: New construction and alterations. 1034.151 Section 1034.151 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION...

  5. How Learners Perceive They Construct Knowledge as Participants in Outreach Programs

    ERIC Educational Resources Information Center

    Yelich Biniecki, Susan

    2010-01-01

    The purpose of this interpretive qualitative research study was to explore how adult learners perceive they construct knowledge in connection to their participation in educational outreach programs, encompassing a continuum of formal, non-formal, and informal learning experiences. The study context involved three world affairs outreach education…

  6. 45 CFR 1181.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section. ...) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES INSTITUTE OF MUSEUM AND LIBRARY SERVICES ENFORCEMENT OF... LIBRARY SERVICES § 1181.151 Program accessibility: New construction and alterations. Each building or...

  7. 45 CFR 1181.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section. ...) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES INSTITUTE OF MUSEUM AND LIBRARY SERVICES ENFORCEMENT OF... LIBRARY SERVICES § 1181.151 Program accessibility: New construction and alterations. Each building or...

  8. Computer program offers new method for constructing periodic orbits in nonlinear dynamical systems

    NASA Technical Reports Server (NTRS)

    Bennett, A. G.; Hanafy, L. M.; Palmore, J. I.

    1968-01-01

    Computer program uses an iterative method to construct precisely periodic orbits which dynamically approximate solutions that converge to precise dynamical solutions in the limit of the sequence. The method used is a modification of the generalized Newton-Raphson algorithm used in analyzing two point boundary problems.

  9. Constructing Reading: Building Conceptions of Literacy in a Volunteer Read-Aloud Program

    ERIC Educational Resources Information Center

    Dawes, Erika Thulin

    2007-01-01

    This study describes the interactions of three adult-child reading partnerships in a program that matches corporate volunteers with "at risk" students for weekly hour-long story reading sessions. Using discourse analysis within a sociocultural framework, the researcher identified variation in the way these partners were constructing the act and…

  10. Dora's Program: A Constructively Marginalized Paraeducator and Her Developmental Biliteracy Program

    ERIC Educational Resources Information Center

    Lucero, Audrey

    2010-01-01

    This article discusses findings from a case study of one elementary bilingual paraeducator, highlighting how the recognition of situated cultural capital enabled her to move from traditional to constructive marginality. I argue that her actions, the actions of others, and conditions within the school enabled her to use culturally relevant funds of…

  11. Military construction program economic analysis manual: Text and appendixes: Hazardous Waste Remedial Actions Program. [Contains glossary

    SciTech Connect

    Not Available

    1987-12-01

    This manual enables the US Air Force to comprehensively and systematically analyze alternative approaches to meeting its military construction requirements. The manual includes step-by-step procedures for completing economic analyses for military construction projects, beginning with determining if an analysis is necessary. Instructions and a checklist of the tasks involved for each step are provided; and examples of calculations and illustrations of completed forms are included. The manual explains the major tasks of an economic analysis, including identifying the problem, selecting realistic alternatives for solving it, formulating appropriate assumptions, determining the costs and benefits of the alternatives, comparing the alternatives, testing the sensitivity of major uncertainties, and ranking the alternatives. Appendixes are included that contain data, indexes, and worksheets to aid in performing the economic analyses. For reference, Volume 2 contains sample economic analyses that illustrate how each form is filled out and that include a complete example of the documentation required. 6 figs., 12 tabs.

  12. Residential building code compliance: Implications for evaluating the performance of utility residential new construction programs

    SciTech Connect

    Vine, E.

    1996-05-01

    Knowing how well builders comply with (or exceed) energy-related building codes is critical for completing a sound evaluation of utility residential new construction programs and for determining the actual cost-effectiveness of these programs. Obtaining credit from utility regulators for additional energy savings from code compliance in participant houses as a result of the utility program is one of the key options available for utilities for improving the cost-effectiveness of these programs. In this paper, the authors examine residential building energy code compliance and specific code violations in three states (California, Oregon and Washington). They then compare residential building energy code compliance for program participants and nonparticipants as well as estimates of the energy savings impacts from noncompliance. The authors also point out some of the methodological limitations of these studies which limit the ability to generalize from these studies.

  13. Concept document of the repository-based software engineering program: A constructive appraisal

    NASA Technical Reports Server (NTRS)

    1992-01-01

    A constructive appraisal of the Concept Document of the Repository-Based Software Engineering Program is provided. The Concept Document is designed to provide an overview of the Repository-Based Software Engineering (RBSE) Program. The Document should be brief and provide the context for reading subsequent requirements and product specifications. That is, all requirements to be developed should be traceable to the Concept Document. Applied Expertise's analysis of the Document was directed toward assuring that: (1) the Executive Summary provides a clear, concise, and comprehensive overview of the Concept (rewrite as necessary); (2) the sections of the Document make best use of the NASA 'Data Item Description' for concept documents; (3) the information contained in the Document provides a foundation for subsequent requirements; and (4) the document adequately: identifies the problem being addressed; articulates RBSE's specific role; specifies the unique aspects of the program; and identifies the nature and extent of the program's users.

  14. A constructive Indian country response to the evidence-based program mandate.

    PubMed

    Walker, R Dale; Bigelow, Douglas A

    2011-01-01

    Over the last 20 years governmental mandates for preferentially funding evidence-based "model" practices and programs has become doctrine in some legislative bodies, federal agencies, and state agencies. It was assumed that what works in small sample, controlled settings would work in all community settings, substantially improving safety, effectiveness, and value-for-money. The evidence-based "model" programs mandate has imposed immutable "core components," fidelity testing, alien programming and program developers, loss of familiar programs, and resource capacity requirements upon tribes, while infringing upon their tribal sovereignty and consultation rights. Tribal response in one state (Oregon) went through three phases: shock and rejection; proposing an alternative approach using criteria of cultural appropriateness, aspiring to evaluability; and adopting logic modeling. The state heard and accepted the argument that the tribal way of knowing is different and valid. Currently, a state-authorized tribal logic model and a review panel process are used to approve tribal best practices for state funding. This constructive response to the evidence-based program mandate elevates tribal practices in the funding and regulatory world, facilitates continuing quality improvement and evaluation, while ensuring that practices and programs remain based on local community context and culture. This article provides details of a model that could well serve tribes facing evidence-based model program mandates throughout the country. PMID:22400457

  15. Community Building Services Training Program: A Model Training Program to Provide Technical Training for Minority Adults in Construction, Building Maintenance,and Property Management. Final Report.

    ERIC Educational Resources Information Center

    Community Building Maintenance Corp., Chicago, IL.

    A demonstration program, administered by a community based building maintenance, management, and construction corporation, was developed to provide technical training for minority adults in construction, building maintenance, and property management in the Chicago area. The program was concerned with seeking solutions to the lack of housing, job…

  16. 25 CFR 1000.240 - What construction programs included in an AFA are subject to this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., coordination, responsibility for the construction project, day-to-day on-site management on site-management and... procurement except that all project design and actual construction activities are subject to all the... 25 Indians 2 2010-04-01 2010-04-01 false What construction programs included in an AFA are...

  17. Evaluating a Teacher Education Program: A Study of the Social and Personal Construction of the Concept "Model-Based Instruction."

    ERIC Educational Resources Information Center

    Steinley, Gary; Penrod, Kathryn; Reisetter, Marcy

    This paper reports the results of a program-evaluation process used by faculty of an undergraduate teacher education department in a mid-sized university; reports findings related to how program participants socially constructed the concept of Model-Based Instruction (MBI) over 9 years; and discusses how individuals constructed the concept of MBI.…

  18. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What is the Tribe's/Consortium's role in a construction program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following...

  19. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What is the Tribe's/Consortium's role in a construction program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following...

  20. Predators of knowledge construction: Interpreting students' metacognition in an amusement park physics program

    NASA Astrophysics Data System (ADS)

    Anderson, David; Nashon, Samson

    2007-03-01

    It is recognized widely that learning is a dynamic and idiosyncratic process of construction and reconstruction of concepts in response to new experiences. It is influenced by the learner's prior knowledge, motivation, and sociocultural context. This study investigated how year 11 and 12 physics students' metacognition influences the development of their conceptual understandings of kinematics. An interpretive case study approach was used to investigate students working in collaborative groups in the context of an amusement park physics program. The metacognitive character of individual learners was demonstrated to have a strong influence on their conceptual development. Moreover, the metacognitive character of individuals within the small group contexts investigated was a key factor influencing the groups' collective knowledge development. A coyote-rabbit metaphor was developed to interpret the resilience and weaknesses of individual and group knowledge construction processes, and elucidates new theoretical understandings regarding metacognition and its influence on knowledge construction.

  1. The Jefferson Lab Quality Assurance Program for the SNS Superconducting Linac Construction Project

    SciTech Connect

    Joseph Ozelis

    2003-05-12

    As part of a multi-laboratory collaboration, Jefferson Lab is currently engaged in the fabrication, assembly, and testing of 23 cryomodules for the superconducting linac portion of the Spallation Neutron Source (SNS) being built at Oak Ridge National Laboratory. As with any large accelerator construction project, it is vitally important that these components be built in a cost effective and timely manner, and that they meet the stringent performance requirements dictated by the project specifications. A comprehensive Quality Assurance (QA) program designed to help accomplish these goals has been implemented as an inherent component of JLab's SNS construction effort. This QA program encompasses the traditional spectrum of component performance, from incoming parts inspection, raw materials testing, through to sub-assembly and finished article performance evaluation.

  2. Fluid-phase interaction of C1 inhibitor (C1 Inh) and the subcomponents C1r and C1s of the first component of complement, C1.

    PubMed

    Chesne, S; Villiers, C L; Arlaud, G J; Lacroix, M B; Colomb, M G

    1982-01-01

    Interactions between proenzymic or activated complement subcomponents of C1 and C1 Inh (C1 inhibitor) were analysed by sucrose-density-gradient ultracentrifugation and sodium dodecyl sulphate/polyacrylamide-gel electrophoresis. The interaction of C1 Inh with dimeric C1r in the presence of EDTA resulted into two bimolecular complexes accounting for a disruption of C1r. The interaction of C1 Inh with the Ca2+-dependent C1r2-C1s2 complex (8.8 S) led to an 8.5 S inhibited C1r-C1s-C1 Inh complex (1:1:2), indicating a disruption of C1r2 and of C1s2 on C1 Inh binding. The 8.5 S inhibited complex was stable in the presence of EDTA; it was also formed from a mixture of C1r, C1s and C1 Inh in the presence of EDTA or from bimolecular complexes of C1r-C1 Inh and C1s-C1 Inh. C1r II, a modified C1r molecule, deprived of a Ca2+-binding site after autoproteolysis, did not lead to an inhibited tetrameric complex on incubation with C1s and C1 Inh. These findings suggest that, when C1 Inh binds to C1r2-C1s2 complex, the intermonomer links inside C1r2 or C1s2 are weakened, whereas the non-covalent Ca2+-independent interaction between C1r2 and C1s2 is strengthened. The nature of the proteinase-C1 Inh link was investigated. Hydroxylamine (1M) was able to dissociate the complexes partially (pH 7.5) or totally (pH 9.0) when the incubation was performed in denaturing conditions. An ester link between a serine residue at the active site of C1r or C1s and C1 Inh is postulated. PMID:6282262

  3. Construction safety program for the National Ignition Facility, July 30, 1999

    SciTech Connect

    Benjamin, D W

    1999-07-30

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and start-up of NIF at LLNL during the construction period of NIF. During this period, all workers are required to implement measures to create a universal awareness which promotes safe practice at the work site, and which will achieve NIF's management objectives in preventing accidents and illnesses. Construction safety for NIF is predicated on everyone performing their jobs in a manner that prevents job-related disabling injuries and illnesses. Integrated Safety Management (ISM) is practiced in the execution of all activities associated with the NIF Project. The seven Principles of ISM are: (1) Line management is responsible for safety. (2) Clear roles and responsibilities are established and maintained. (3) Personnel possess competence commensurate with responsibilities. (4) Resource allocations are balanced, making ES and H a priority in project planning and execution. (5) Safety requirements are identified and implemented. (6) Hazard controls are tailored to the project work. (7) Operations are authorized before work begins.

  4. Psychosocial well-being construct in people with severe mental disorders enrolled in supported employment programs.

    PubMed

    Negrini, Alessia; Corbière, Marc; Fortin, Guillaume; Lecomte, Tania

    2014-11-01

    The main purpose of this prospective study is to validate the construct of psychosocial well-being (PSWB) for people with severe mental disorders enrolled in Supported Employment (SE) programs. This paper also aims to assess the impact of job acquisition on PSWB after obtaining competitive employment. A two-phase study approach was used and 231 individuals with severe mental disorders enrolled in SE programs who took part in both phases. The shortened versions of the Psychological Well-Being Scale (Keyes et al. in J Personal Soc Psychol, 82(6):1007-1022, 2002; Ryff and Keyes in J Personal Soc Psychol 69(4):719-727, 1995) and the Social Well-Being Scale (Keyes in Soc Psychol Q 61(2):121-140, 1998) were used. The PSWB's multidimensionality construct was confirmed. The results of repeated measure ANOVA analyses revealed that job acquisition, as well as, being involved in a work-seeking process increase the PSWB of people with severe mental disorders. Employment specialists might find clinical utility in using this validated tool for assessing PSWB in their clients with severe mental disorders. In a recovery oriented approach to psychiatric services and SE programs, clinicians and employment specialists should continue to encourage their clients in their work integration process even though they may not all obtain competitive employment quickly. PMID:24771294

  5. Northwest Energy Efficient Manufactured Housing Program: High Performance Manufactured Home Prototyping and Construction Development

    SciTech Connect

    Hewes, Tom; Peeks, Brady

    2013-11-01

    The Building America Partnership for Improved Residential Construction, the Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Housing Program (NEEM) administrator, have been collaborating to conduct research on new specifications that would improve on the energy requirements of a NEEM home. In its role as administrator, NEW administers the technical specs, performs research and engineering analysis, implements ongoing construction quality management procedures, and maintains a central database with home tracking. This project prototyped and assessed the performances of cost-effective high performance building assemblies and mechanical systems that are not commonly deployed in the manufacturing setting. The package of measures is able to reduce energy used for space conditioning, water heating and lighting by 50% over typical manufactured homes produced in the northwest.

  6. Northwest Energy Efficient Manufactured Housing Program: High Performance Manufactured Home Prototyping and Construction Development

    SciTech Connect

    Hewes, T.; Peeks, B.

    2013-11-01

    The Building America Partnership for Improved Residential Construction, the Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Housing Program (NEEM) administrator, have been collaborating to conduct research on new specifications that would improve on the energy requirements of a NEEM home. In its role as administrator, NEW administers the technical specs, performs research and engineering analysis, implements ongoing construction quality management procedures, and maintains a central database with home tracking. This project prototyped and assessed the performances of cost-effective high performance building assemblies and mechanical systems that are not commonly deployed in the manufacturing setting. The package of measures is able to reduce energy used for space conditioning, water heating and lighting by 50 percent over typical manufactured homes produced in the northwest.

  7. EPA construction grants: Information on the Milwaukee Area Sewerage System Improvement Program

    SciTech Connect

    Not Available

    1986-01-01

    The Milwaukee Sewerage Water Pollution Abatement Program was initiated in response to federal and state court lawsuits to halt Lake Michigan's pollution. It is about $360 million under budget and on schedule with a 1996 target completion date. GAO found that the district meets the federal criteria for an eligible grantee; federal and Wisconsin regulations permit architect and engineering contracts to be competitively negotiated and do not require advertised competitive bidding; the job site rule, which limits allowable overhead billings, was not applied because it was determined that the operation of the prime contractor responsible for managing the program and its technical integrity did not constitute a job site; no federal funds have been involved in the disposition of rock from the north shore project site; and the total estimated architect and engineering costs $344.7 million represent about 28 percent of total estimated construction costs.

  8. C1q and systemic lupus erythematosus.

    PubMed

    Walport, M J; Davies, K A; Botto, M

    1998-08-01

    In this chapter we review the association between SLE and C1q. In the first part of the chapter we discuss the clinical associations of C1q deficiency, and tabulate the available information in the literature relating to C1q deficiency and autoimmune disease. Other clinical associations of C1q deficiency are then considered, and we mention briefly the association between other genetically determined complement deficiencies and lupus. In the review we explore the relationship between C1q consumption and lupus and we discuss the occurrence of low molecular weight (7S) C1q in lupus, which raises the possibility that increased C1q turnover in the disease may result in unbalanced chain synthesis of the molecule. Anti-C1q antibodies are also strongly associated with severe SLE affecting the kidney, and with hypocomplementaemic urticarial vasculitis, and these associations are also examined. We address the question of how C1q deficiency may cause SLE, discussing the possibility that this may be due to abnormalities of immune complex processing, which have been well characterised in a umber of different human models. There is clear evidence that immune complex processing is abnormal in patients with hypocomplementaemia, and this is compatible with the hypothesis that ineffective immune complex clearance could cause tissue injury, and this may in turn stimulate an autoantibody response. We have also considered the possibility that C1q-C1q receptor interactions are critical in the regulation of apoptosis, and we explore the hypothesis that dysregulation of apoptosis could explain important features in the development of autoimmune disease associated with C1q deficiency. An abnormally high rate of apoptosis, or defective clearance of apoptotic cells, could promote the accumulation of abnormal cellular products that might drive an autoimmune response. Anti-C1q antibodies have been described in a number of murine models of lupus, and these are also briefly discussed. We focus

  9. Autoantibodies against complement C1q specifically target C1q bound on early apoptotic cells.

    PubMed

    Bigler, Cornelia; Schaller, Monica; Perahud, Iryna; Osthoff, Michael; Trendelenburg, Marten

    2009-09-01

    Autoantibodies against complement C1q (anti-C1q) are frequently found in patients with systemic lupus erythematosus (SLE). They strongly correlate with the occurrence of severe lupus nephritis, suggesting a pathogenic role in SLE. Because anti-C1q are known to recognize a neoepitope on bound C1q, but not on fluid-phase C1q, the aim of this study was to clarify the origin of anti-C1q by determining the mechanism that renders C1q antigenic. We investigated anti-C1q from serum and purified total IgG of patients with SLE and hypocomplementemic urticarial vasculitis as well as two monoclonal human anti-C1q Fab from a SLE patient generated by phage display. Binding characteristics, such as their ability to recognize C1q bound on different classes of Igs, on immune complexes, and on cells undergoing apoptosis, were analyzed. Interestingly, anti-C1q did not bind to C1q bound on Igs or immune complexes. Neither did we observe specific binding of anti-C1q to C1q bound on late apoptotic/necrotic cells when compared with binding in the absence of C1q. However, as shown by FACS analysis and confocal microscopy, anti-C1q specifically targeted C1q bound on early apoptotic cells. Anti-C1q were found to specifically target C1q bound on cells undergoing apoptosis. Our observations suggest that early apoptotic cells are a major target of the autoimmune response in SLE and provide a direct link between human SLE, apoptosis, and C1q. PMID:19648280

  10. Scientific program construction principles and time allocation scheme for the World Space Observatory—Ultraviolet mission

    NASA Astrophysics Data System (ADS)

    Malkov, Oleg; Sachkov, Mikhail; Shustov, Boris; Kaigorodov, Pavel; Yáñez, Francisco Javier; Gómez de Castro, Ana Ines

    2011-09-01

    We present scientific program construction principles and a time allocation scheme developed for the World Space Observatory—Ultraviolet (WSO-UV) mission, which is an international space observatory for observation in UV spectral range 100-300 nm. The WSO-UV consists of a 1.7 m aperture telescope with instrumentation designed to carry out high resolution spectroscopy, long-slit low resolution spectroscopy and direct sky imaging. The WSO-UV Ground Segment is under development by Spain and Russia. They will coordinate the Mission and Science Operations and provide the satellite tracking stations for the project. The WSO-UV will work as a targeted scientific observatory. Three scientific programs will be carried out at the observatory. Core Program of scientific observations, which deserves large amounts of observing time, will be defined by the WSO-UV Science Committee to allow the conduction of high impact or legacy scientific projects. Funding Bodies Program is the guaranteed time granted to each one of the national bodies funding the WSO-UV project. Guest observer program for everyone, or Open Program, consists of astronomical observations obtained with the WSO-UV by astronomers who may or may not belong to the WSO-UV international consortium. It is open to excellent scientific projects from the world-wide community and occupies up to 40% of total observational time. Apart from the particularities associated to a science mission, this new mission will be affected by a new concept of observations management, trying to maximize the scientific return of this mission, and the shared operations between the two sites located in Spain and Russia. A brief summary of the algorithmic strategies analyzed for scheduling optimization is also given in the paper.

  11. Employers' Perception of Graduates with Entry-Level Technical Skills from Construction Industry Programs in Ghana and Nigeria

    ERIC Educational Resources Information Center

    Acheampong, Philip

    2013-01-01

    The purpose of this comparative study was to identify the technical skills and abilities needed by prospective employees of construction industries in Ghana and Nigeria. Potential employees were defined here as recent graduates of construction industry programs with entry-level technical skills. The continuous growth in and expansion of these two…

  12. C1 neurons: the body's EMTs.

    PubMed

    Guyenet, Patrice G; Stornetta, Ruth L; Bochorishvili, Genrieta; Depuy, Seth D; Burke, Peter G R; Abbott, Stephen B G

    2013-08-01

    The C1 neurons reside in the rostral and intermediate portions of the ventrolateral medulla (RVLM, IVLM). They use glutamate as a fast transmitter and synthesize catecholamines plus various neuropeptides. These neurons regulate the hypothalamic pituitary axis via direct projections to the paraventricular nucleus and regulate the autonomic nervous system via projections to sympathetic and parasympathetic preganglionic neurons. The presympathetic C1 cells, located in the RVLM, are probably organized in a roughly viscerotopic manner and most of them regulate the circulation. C1 cells are variously activated by hypoglycemia, infection or inflammation, hypoxia, nociception, and hypotension and contribute to most glucoprivic responses. C1 cells also stimulate breathing and activate brain stem noradrenergic neurons including the locus coeruleus. Based on the various effects attributed to the C1 cells, their axonal projections and what is currently known of their synaptic inputs, subsets of C1 cells appear to be differentially recruited by pain, hypoxia, infection/inflammation, hemorrhage, and hypoglycemia to produce a repertoire of stereotyped autonomic, metabolic, and neuroendocrine responses that help the organism survive physical injury and its associated cohort of acute infection, hypoxia, hypotension, and blood loss. C1 cells may also contribute to glucose and cardiovascular homeostasis in the absence of such physical stresses, and C1 cell hyperactivity may contribute to the increase in sympathetic nerve activity associated with diseases such as hypertension. PMID:23697799

  13. C1 neurons: the body's EMTs

    PubMed Central

    Stornetta, Ruth L.; Bochorishvili, Genrieta; DePuy, Seth D.; Burke, Peter G. R.; Abbott, Stephen B. G.

    2013-01-01

    The C1 neurons reside in the rostral and intermediate portions of the ventrolateral medulla (RVLM, IVLM). They use glutamate as a fast transmitter and synthesize catecholamines plus various neuropeptides. These neurons regulate the hypothalamic pituitary axis via direct projections to the paraventricular nucleus and regulate the autonomic nervous system via projections to sympathetic and parasympathetic preganglionic neurons. The presympathetic C1 cells, located in the RVLM, are probably organized in a roughly viscerotopic manner and most of them regulate the circulation. C1 cells are variously activated by hypoglycemia, infection or inflammation, hypoxia, nociception, and hypotension and contribute to most glucoprivic responses. C1 cells also stimulate breathing and activate brain stem noradrenergic neurons including the locus coeruleus. Based on the various effects attributed to the C1 cells, their axonal projections and what is currently known of their synaptic inputs, subsets of C1 cells appear to be differentially recruited by pain, hypoxia, infection/inflammation, hemorrhage, and hypoglycemia to produce a repertoire of stereotyped autonomic, metabolic, and neuroendocrine responses that help the organism survive physical injury and its associated cohort of acute infection, hypoxia, hypotension, and blood loss. C1 cells may also contribute to glucose and cardiovascular homeostasis in the absence of such physical stresses, and C1 cell hyperactivity may contribute to the increase in sympathetic nerve activity associated with diseases such as hypertension. PMID:23697799

  14. Relating Women's Experience and Skills to Competencies Required in Selected Occupations and Vocational Education Programs. Project Report, Task C1, Revised Competency Analysis: Credentialing Women's Life Experiences (Project ACCESS).

    ERIC Educational Resources Information Center

    Ekstrom, Ruth B.; And Others

    Competency scales were developed for 10 direct-entry occupations and 10 vocational education programs as part of Project ACCESS, a project to assess women's life experience learning for entrance into employment and for advanced placement in vocational education programs. Development of the occupational scales involved employer interviews, followed…

  15. 1975-76 Pennsylvania Adult Basic Education Assessment Project: An Examination of the APL Construct and Mezirow's Program Evaluation Model as a Basis for Program Improvement. Final Report.

    ERIC Educational Resources Information Center

    Lindsay, Carl A.; And Others

    A project was conducted in Pennsylvania to determine what changes might improve the effectiveness of the State's adult basic education (ABE) program. Northcutt's construct of functional competency adult performance level (APL) and Mezirow's program evaluation model provided the basis for the project's two components: APL assessment and program…

  16. Twin Falls Public Library, Idaho Final Performance Report for Library Services and Construction Act Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Parkinson, Linda L.; Burton, Annie Laurie

    The grant received for the Literacy Program of the Twin Falls (Idaho) Public Library (approximately $24,000) has contributed to the overall improvement of the library system afforded by construction of a new addition planned for completion in February 1991. Grant funds supporting the literacy program complemented funds from a bond issue for…

  17. The cultural construction of interdisciplinarity: Doctoral student socialization in an interdisciplinary neuroscience program

    NASA Astrophysics Data System (ADS)

    Holley, Karri A.

    Using the methodologies of individual and group interviews, observation, and document analysis, this dissertation examines the experiences of doctoral students enrolled in an interdisciplinary neuroscience program. A framework drawn from theories of organizational socialization is employed to understand the influence of an interdisciplinary program on doctoral student socialization. While abundant previous literature exists in regards to the socialization of doctoral students, such literature largely concentrates the disciplinary experience. The escalating import of globalization and shifting fiscal realities place new demands on Ph.D. programs and doctoral students to work as part of collaborative research teams, produce interdisciplinary knowledge, and integrate theory and practice. The increasing influence of such factors requires a new focus on interdisciplinarity and the changing Ph.D. The goal of this dissertation is to expand the existing framework of socialization by documenting the influence of such obstacles on knowledge acquisition, identity development, and professional investment. This study focuses on how interdisciplinary identities are constructed by doctoral students through individual interaction with the social environment and cultural context. Particular attention is given to the structural and cultural obstacles that doctoral students must negotiate as they navigate an interdisciplinary program. The study expands on the previous literature regarding doctoral student socialization by focusing on identity development, specifically a student's symbolic identity as a neuroscientist, a student's disciplinary identity (related to her professional background and undergraduate experiences), and a multi-disciplinary identity that allows for connections across disciplinary boundaries. In contrast to the traditional concepts of identity which focus on boundaries and differences as an inherent part of self-definition, the structure of identity advanced

  18. Posterior osseous bridging of C1.

    PubMed

    Simsek, Serkan; Yigitkanli, Kazim; Comert, Ayhan; Acar, Halil I; Seckin, Hakan; Er, Uygur; Belen, Deniz; Tekdemir, Ibrahim; Elhan, Alaittin

    2008-06-01

    The sulcus of the vertebral artery is located behind the lateral mass of the atlas and in some cases is converted into a foramen by anomalous ossification known as the posterior ponticulus (osseous bridge). This study involved anatomical observations of 158 isolated anatomical specimens of dry C1 vertebrae. The incidence and types of posterior osseous bridging were identified for the 158 dry samples of atlas vertebrae. In nine (5.6%) dry C1 vertebrae, partial osseous bridging was detected (bilaterally in eight vertebrae and unilaterally on the left in one). Complete osseous bridging (arcuate foramen) was observed in six (3.8%) dry C1 vertebrae (bilaterally in one vertebra, unilaterally on the left in three, and on the right in two). Awareness of the types of posterior osseous bridging of C1 in craniocervical junction surgery is essential, and may be helpful in surgical interventions in this region. PMID:18378457

  19. Anti-C1q autoantibodies.

    PubMed

    Kallenberg, Cees G M

    2008-09-01

    Autoantibodies to complement components are associated with various diseases. Anti-C1q antibodies are present in all patients with hypocomplementemic urticarial vasculitis, but also, with varying prevalence, in other conditions. In SLE, these antibodies are neither sensitive nor specific for this condition. They occur, however, more frequently in (proliferative) lupus nephritis, particularly during active disease. Furthermore, levels of anti-C1q rise, in many cases, prior to a relapse of lupus nephritis, suggesting a pathogenic role for the autoantibodies. Indeed, experimental studies strongly support a pathogenic role for anti-C1q in immune complex-mediated renal disease. In addition, anti-C1q may interfere with the clearance of apoptotic cells, so influencing induction and expression of autoimmunity. PMID:18606253

  20. Career Guidance, Counseling, Placement, and Follow-Through Program for Rural Schools. Career Guidance and Counseling for Groups and Individuals. Career Counseling in the Rural School. Research and Development Series Number 118 C1.

    ERIC Educational Resources Information Center

    Hartz, John D.; Kosmo, Susan J.

    Materials contained in the 16 volumes that make up the Rural America Series suggest practices through which rural schools can meet local community needs and realize their potential for career program delivery. This handbook for rural school counselors, one of five in subset C of the series, provides a basic rationale for career counseling and a…

  1. Construction Technologies.

    ERIC Educational Resources Information Center

    Columbus State Community Coll., OH.

    This document contains materials developed for and about the construction technologies tech prep program of the South-Western City Schools in Ohio. Part 1 begins with a map of the program, which begins with a construction technologies program in grades 11 and 12 that leads to entry-level employment or one of five 2-year programs at a community…

  2. Accurate and interpretable nanoSAR models from genetic programming-based decision tree construction approaches.

    PubMed

    Oksel, Ceyda; Winkler, David A; Ma, Cai Y; Wilkins, Terry; Wang, Xue Z

    2016-09-01

    The number of engineered nanomaterials (ENMs) being exploited commercially is growing rapidly, due to the novel properties they exhibit. Clearly, it is important to understand and minimize any risks to health or the environment posed by the presence of ENMs. Data-driven models that decode the relationships between the biological activities of ENMs and their physicochemical characteristics provide an attractive means of maximizing the value of scarce and expensive experimental data. Although such structure-activity relationship (SAR) methods have become very useful tools for modelling nanotoxicity endpoints (nanoSAR), they have limited robustness and predictivity and, most importantly, interpretation of the models they generate is often very difficult. New computational modelling tools or new ways of using existing tools are required to model the relatively sparse and sometimes lower quality data on the biological effects of ENMs. The most commonly used SAR modelling methods work best with large datasets, are not particularly good at feature selection, can be relatively opaque to interpretation, and may not account for nonlinearity in the structure-property relationships. To overcome these limitations, we describe the application of a novel algorithm, a genetic programming-based decision tree construction tool (GPTree) to nanoSAR modelling. We demonstrate the use of GPTree in the construction of accurate and interpretable nanoSAR models by applying it to four diverse literature datasets. We describe the algorithm and compare model results across the four studies. We show that GPTree generates models with accuracies equivalent to or superior to those of prior modelling studies on the same datasets. GPTree is a robust, automatic method for generation of accurate nanoSAR models with important advantages that it works with small datasets, automatically selects descriptors, and provides significantly improved interpretability of models. PMID:26956430

  3. Satellite Power System. Concept development and evaluation program, volume 6: Construction and operations

    NASA Technical Reports Server (NTRS)

    Benson, H.; Jenkins, L. M.

    1981-01-01

    The construction, operation, and maintenance requirements for a solar power satellite, including the space and ground systems, are reviewed. The basic construction guidelines are explained, and construction location options are discussed. The space construction tasks, equipment, and base configurations are discussed together with the operations required to place a solar power satellite in geosynchronous orbit. A rectenna construction technique is explained, and operation with the grid is defined. Maintenance requirements are summarized for the entire system. Key technology issues required for solar power satellite construction operations are defined.

  4. Hereditary angioedema with normal C1 inhibitor.

    PubMed

    Bork, Konrad

    2013-11-01

    Until recently it was assumed that hereditary angioedema was a disease that results exclusively from a genetic deficiency of the C1 inhibitor. In 2000, families with hereditary angioedema, normal C1 inhibitor activity, and protein in plasma were described. Since then, numerous patients and families with that condition have been reported. Most of the patients were women. In many of the affected women, oral contraceptives, hormone replacement therapy containing estrogens, and pregnancies triggered the clinical symptoms. In some families mutations in the coagulation factor XII (Hageman factor) gene were detected. PMID:24176211

  5. C1 Hermite shape preserving polynomial splines in R3

    NASA Astrophysics Data System (ADS)

    Gabrielides, Nikolaos C.

    2012-06-01

    The C 2 variable degree splines1-3 have been proven to be an efficient tool for solving the curve shape-preserving interpolation problem in two and three dimensions. Based on this representation, the current paper proposes a Hermite interpolation scheme, to construct C 1 shape-preserving splines of variable degree. After this, a slight modification of the method leads to a C 1 shape-preserving Hermite cubic spline. Both methods can easily be developed within a CAD system, since they compute directly (without iterations) the B-spline control polygon. They have been implemented and tested within the DNV Software CAD/CAE system GeniE. [Figure not available: see fulltext.

  6. Construction of an Optimal Background Profile for the Kuramoto-Sivashinsky Equation using Semidefinite Programming

    NASA Astrophysics Data System (ADS)

    Wynn, Andrew; Fantuzzi, Giovanni

    2014-11-01

    The Kuramoto-Sivashinsky (KS) equation has been derived in many physical contexts to describe systems whose dynamics are characterised by long-wavelength instability, for example flame-front instabilities or flow stability for thin liquid films on inclined planes. It is known that the KS equation has chaotic solutions if the governing parameter (typically the length L of the domain) is sufficiently large. Furthermore, numerical evidence suggests that the asymptotic energy of the solution scales according to L1/2 although, despite much effort, it has not yet been possible to prove such a bound analytically. We present a novel method of proving bounds on the asymptotic energy of the KS equation, by constructing a `background profile' using Semidefinite Programming. The advantage of the method is that the background profile may be searched for automatically by solving a standard optimization problem, while coupling the numerics to a careful mathematical analysis of the PDE ensures that the bounds hold analytically. The obtained scaling of L3/2 agrees with the previous best results using the background profile method. Interestingly, the obtained profiles closely resemble the `viscous shock' solutions which are known to exist for destabilized KS equations.

  7. Non-Native English-Speaking Teachers' Negotiations of Program Discourses in Their Construction of Professional Identities within a TESOL Program

    ERIC Educational Resources Information Center

    Ilieva, Roumi

    2010-01-01

    The professional identity of language teachers has gained prominence in research on language instruction in the last decade. This article adds to work by critically exploring how teacher education programs allow non-native English-speaking teachers (NNESTs) to construct positive professional identities and become pro-active educators. It reports…

  8. Library Services for Indian Tribes and Hawaiian Natives Program: Review of Program Activities, 1990. Title IV, Library Services and Construction Act.

    ERIC Educational Resources Information Center

    Fine, Beth, Comp.; Woolen, Viola, Comp.

    THe Library Services for Indian Tribes and Hawaiian natives Program, Title IV of the Library Services and Construction Act (LSCA), supports public library services to Indians and Hawaiian Natives. Two types of grants--Basic Grants and Special Projects--encourage the development and improvement of public library services through selected project…

  9. "The Mall" and "the Plant": Choice and the Classed Construction of Possible Futures in Two Specialized Arts Programs

    ERIC Educational Resources Information Center

    Gaztambide-Fernández, Rubén; VanderDussen, Elena; Cairns, Kate

    2014-01-01

    This article explores how conceptions of choice and visions of the future are constructed within the context of specialized arts programs in two Canadian public high schools. The authors consider how discourses of the arts are implicated in the way that possible futures are envisioned differently, delimiting the range of choices available to…

  10. Construction work practices and conditions improved after 2-years' participation in the HomeSafe pilot program.

    PubMed

    Gilkey, David P; Hautaluoma, Jacob E; Ahmed, Taslim P; Keefe, Thomas J; Herron, Robert E; Bigelow, Philip L

    2003-01-01

    This study reevaluated changes in job-site safety audit scores for a cohort of residential construction workers that had protracted exposure to the HomeSafe pilot program for 2(1/2) years. The investigation was a repeated measure of a cohort study underway in the six-county metro area of Denver, Colo. The larger study was a longitudinal, quasi-experimental design with a cohort of residential construction workers within the HomeSafe strategic partnership between Occupational Safety and Health Administration Region VIII and the Home Builders Association of Metropolitan Denver (HBA). Audits were conducted on residential construction sites. Study subjects were construction workers employed by partner or control companies within the study. Repeated measures of 41 companies showed significant improvement (p=.01) in audit scores, increasing from 71.8 to 76.8 after 2(1/2) years in the program. HomeSafe companies out-performed controls (p=.01) for both the retest group and previously unaudited HomeSafe companies. Prolonged exposure in the HomeSafe pilot program resulted in improved audit scores for companies within the program for at least 2 years. PMID:12809540

  11. A Study of the Construct Validity of Six Vocational Achievement Tests in the Ohio Vocational Education Achievement Test Program.

    ERIC Educational Resources Information Center

    Hines, Constance V.; And Others

    A study examined the construct validity of six vocational achievement tests used in the Ohio Vocational Achievement Testing Program. (Subject areas covered in the tests were agricultural mechanics, carpentry, diesel mechanics, distributive education for food services personnel, fabric services, and home economics/food service.) In order to…

  12. 25 CFR 1000.243 - What special provisions must be included in an AFA that contains a construction program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What special provisions must be included in an AFA that contains a construction program? 1000.243 Section 1000.243 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT...

  13. When the School Bell Rings... Juvenile Crime or Constructive Time? After-School Programs Are the Answer.

    ERIC Educational Resources Information Center

    Carpenter, Tim; Cornelius, Aisha; Francis, Ann Potter; Parsons, Lena

    Noting that the after-school hours are peak hours for Illinois juveniles to be either victims of crime or involved in criminal activity, this report provides evidence that making quality after-school programs available to all youth who need them will reduce crime and provide constructive activities for youth. The report details statistics on…

  14. Program Evaluation Project Report, 1969-1973. Chapter Five: A Construct Validity Overview of Goal Attainment Scaling.

    ERIC Educational Resources Information Center

    Garwick, Geoffrey

    The P.E.P. Report 1969-1973 focuses on the various findings and activities of the Program Evaluation Project. The establishment of validity is one of the major tasks of the developers of a measurement methodology. In this chapter, it is argued that the construct validity approach is essential to an understanding of the validity of Goal Attainment…

  15. Men's Adultery as Sickness: Metaphor, Gender Categories and the Discursive Construction of Gender Differences on Japanese Television Consultation Programs

    ERIC Educational Resources Information Center

    Saft, Scott; Ohara, Yumiko

    2009-01-01

    This article describes how Japanese TV programs adopting a consultation framework construct different realities for women and men concerning a specific social phenomenon, namely adultery. To do so, two perspectives, the theory of metaphor promoted by George Lakoff and membership category analysis, are combined toward a discursive analysis which…

  16. Massachusetts Long-Range Program Under Library Services and Construction Act (P.L. 91-600).

    ERIC Educational Resources Information Center

    Massachusetts State Dept. of Education, Boston. Bureau of Library Extension.

    As required under the Library Services and Construction Act, Massachusetts has developed a long-range program document delineating its goals, sub-goals, and objectives for library services. The overall goal for library service is to provide all residents of the Commonwealth access to those library and information resources which will satisfy their…

  17. Lessons learned from new construction utility demand side management programs and their implications for implementing building energy codes

    SciTech Connect

    Wise, B.K.; Hughes, K.R.; Danko, S.L.; Gilbride, T.L.

    1994-07-01

    This report was prepared for the US Department of Energy (DOE) Office of Codes and Standards by the Pacific Northwest Laboratory (PNL) through its Building Energy Standards Program (BESP). The purpose of this task was to identify demand-side management (DSM) strategies for new construction that utilities have adopted or developed to promote energy-efficient design and construction. PNL conducted a survey of utilities and used the information gathered to extrapolate lessons learned and to identify evolving trends in utility new-construction DSM programs. The ultimate goal of the task is to identify opportunities where states might work collaboratively with utilities to promote the adoption, implementation, and enforcement of energy-efficient building energy codes.

  18. Improving safety climate through a communication and recognition program for construction: a mixed-methods study

    PubMed Central

    Sparer, Emily H; Catalano, Paul J; Herrick, Robert F; Dennerlein, Jack T

    2016-01-01

    Objectives This study aimed to evaluate the efficacy of a safety communication and recognition program (B-SAFE), designed to encourage improvement of physical working conditions and hazard reduction in construction. Methods A matched pair cluster randomized controlled trial was conducted on eight worksites (four received the B-SAFE intervention, four served as control sites) for approximately five months per site. Pre- and post-exposure worker surveys were collected at all sites (N=615, pre-exposure response rate of 74%, post-exposure response rate of 88%). Multi-level mixed-effect regression models evaluated the effect of B-SAFE on safety climate as assessed from surveys. Focus groups (N=6–8 workers/site) were conducted following data collection. Transcripts were coded and analyzed for thematic content using Atlas.ti (version 6). Results The mean safety climate score at intervention sites, as measured on a 0–50 point scale, increased 0.5 points (1%) between pre- and post-B-SAFE exposure, compared to control sites that decreased 0.8 points (1.6%). The intervention effect size was 1.64 (3.28%) (P-value=0.01) when adjusted for month the worker started on-site, total length of time on-site, as well as individual characteristics (trade, title, age, and race/ethnicity). At intervention sites, workers noted increased levels of safety awareness, communication, and teamwork compared to control sites. Conclusions B-SAFE led to many positive changes, including an improvement in safety climate, awareness, teambuilding, and communication. B-SAFE was a simple intervention that engaged workers through effective communication infrastructures and had a significant, positive effect on worksite safety. PMID:27158914

  19. Computer-based construction of gene models using the GRAIL Gene Assembly Program

    SciTech Connect

    Einstein, J.R.; Mural, R.J.; Guan, X.; Uberbacher, E.C.

    1992-09-01

    The Gene Assembly Program (GAP), a module of GRAIL, assembles and scores gene models, given a DNA sequence and the outputs of other GRAIL modules for the sequence. The latter modules determine the positions of coding regions, the positions and scores of possible splice junctions, the positions of possible translation-initiation sites, the coding strand for the gene, and the probable-translation-frame function over the sequence. GAP tests combinations of those splice junctions which are within acceptable distances from the initial estimated edges of the coding regions. Every complete gene model, comprising translation-initiation site, splice junctions and stop codon, which agrees with GAP`s set of rules is scored, and the ten highest-scoring models are saved. Each gene-model score depends on the input scores of splice junctions used in the model, their positions relative to the initial estimated edges of the included coding regions, and the degree of agreement of the entire model with the probable-translation-frame function. If error conditions are detected, the present version of GAP attempts to correct them by the insertion and/or deletion of one or more coding regions. These insertions and deletions have resulted in a net improvement of gene models, and a particularly large improvement in the recognition and characterization of very short coding regions. The results of GRAIL including the GAP module for 26 sequences from GenBank, each with a biochemically characterized single gene, are quite promising and demonstrate the feasibility of constructing largely accurate gene models strictly on the basis of sequence data.

  20. Computer-based construction of gene models using the GRAIL Gene Assembly Program

    SciTech Connect

    Einstein, J.R.; Mural, R.J.; Guan, X.; Uberbacher, E.C.

    1992-09-01

    The Gene Assembly Program (GAP), a module of GRAIL, assembles and scores gene models, given a DNA sequence and the outputs of other GRAIL modules for the sequence. The latter modules determine the positions of coding regions, the positions and scores of possible splice junctions, the positions of possible translation-initiation sites, the coding strand for the gene, and the probable-translation-frame function over the sequence. GAP tests combinations of those splice junctions which are within acceptable distances from the initial estimated edges of the coding regions. Every complete gene model, comprising translation-initiation site, splice junctions and stop codon, which agrees with GAP's set of rules is scored, and the ten highest-scoring models are saved. Each gene-model score depends on the input scores of splice junctions used in the model, their positions relative to the initial estimated edges of the included coding regions, and the degree of agreement of the entire model with the probable-translation-frame function. If error conditions are detected, the present version of GAP attempts to correct them by the insertion and/or deletion of one or more coding regions. These insertions and deletions have resulted in a net improvement of gene models, and a particularly large improvement in the recognition and characterization of very short coding regions. The results of GRAIL including the GAP module for 26 sequences from GenBank, each with a biochemically characterized single gene, are quite promising and demonstrate the feasibility of constructing largely accurate gene models strictly on the basis of sequence data.

  1. Using a commercial CAD system for simultaneous input to theoretical aerodynamic programs and wind-tunnel model construction

    NASA Technical Reports Server (NTRS)

    Enomoto, F.; Keller, P.

    1984-01-01

    The Computer Aided Design (CAD) system's common geometry database was used to generate input for theoretical programs and numerically controlled (NC) tool paths for wind tunnel part fabrication. This eliminates the duplication of work in generating separate geometry databases for each type of analysis. Another advantage is that it reduces the uncertainty due to geometric differences when comparing theoretical aerodynamic data with wind tunnel data. The system was adapted to aerodynamic research by developing programs written in Design Analysis Language (DAL). These programs reduced the amount of time required to construct complex geometries and to generate input for theoretical programs. Certain shortcomings of the Design, Drafting, and Manufacturing (DDM) software limited the effectiveness of these programs and some of the Calma NC software. The complexity of aircraft configurations suggests that more types of surface and curve geometry should be added to the system. Some of these shortcomings may be eliminated as improved versions of DDM are made available.

  2. Libby Mitigation Program, 2007 Annual Progress Report: Mitigation for the Construction and Operation of Libby Dam.

    SciTech Connect

    Dunnigan, James; DeShazer, J.; Garrow, L.

    2009-05-26

    basin streams and lakes. 'Mitigation for the Construction and Operation of Libby Dam' is part of the Northwest Power and Conservation Council's (NPCC) resident fish and wildlife program. The program was mandated by the Northwest Planning Act of 1980, and is responsible for mitigating damages to fish and wildlife caused by hydroelectric development in the Columbia River Basin. The objective of Phase I of the project (1983 through 1987) was to maintain or enhance the Libby Reservoir fishery by quantifying seasonal water levels and developing ecologically sound operational guidelines. The objective of Phase II of the project (1988 through 1996) was to determine the biological effects of reservoir operations combined with biotic changes associated with an aging reservoir. The objectives of Phase III of the project (1996 through present) are to implement habitat enhancement measures to mitigate for dam effects, to provide data for implementation of operational strategies that benefit resident fish, monitor reservoir and river conditions, and monitor mitigation projects for effectiveness. This project completes urgent and high priority mitigation actions as directed by the Kootenai Subbasin Plan.

  3. Evaluation of the Mandatory Construction Induction Training Program in Western Australia: Unanticipated Consequences

    ERIC Educational Resources Information Center

    Bahn, Susanne; Barratt-Pugh, Llandis

    2012-01-01

    Since January 1, 2007, Government legislation in Western Australia required all workers in construction to complete mandatory safety awareness training before they began work on site. During the implementation of this new legislation there was considerable resistance from the construction sector due to the mandatory nature of the training. The…

  4. Paracoccus denitrificans cytochrome c1 gene replacement mutants.

    PubMed Central

    Gerhus, E; Steinrücke, P; Ludwig, B

    1990-01-01

    We describe the construction and characterization of gene replacement mutants for the respiratory chain component cytochrome c1 in the bacterium Paracoccus denitrificans. Its structural gene (fbcC) was inactivated by insertion of the kanamycin resistance gene, introduced into a suicide vector, and conjugated into Paracoccus; chromosomal mutants obtained by homologous recombination were selected by antibiotic resistance screening and further characterized biochemically. They showed the complete spectral, enzymatic, and immunological loss of the fbcC gene product together with a serious defect in the assembly of the two other gene products of the fbc operon, cytochrome b and the FeS protein. A possible role of the cytochrome c1 in the assembly process for the enzyme complex is discussed. A functional restoration to wild-type phenotype was achieved by complementing in trans with a newly constructed broad-host-range vector carrying the fbcC gene cassette. When the complete fbc operon was present on this vector, overexpression of complex III subunits was observed. Apart from their physiological significance, such mutants are a prerequisite for probing structure-function relationships by site-directed mutagenesis in order to understand molecular details of electron transport and energy transduction processes of this respiratory enzyme in bacteria and in mitochondria. Images PMID:2158969

  5. Facility Planning in the Construction Grants Program. Instructor Guide. Working for Clean Water: An Information Program for Advisory Groups.

    ERIC Educational Resources Information Center

    Buskirk, E. Drannon, Jr.; Cole, Charles A.

    Wastewater facility planning is an essential component of the federal construction grants process. Presented in this instructor's guide is a one-hour presentation on facility planning intended for citizen advisory groups. The guide is part of the Working for Clean Water Project, which also includes a supplementary audiovisual presentation.…

  6. C1q protein binds to the apoptotic nucleolus and causes C1 protease degradation of nucleolar proteins.

    PubMed

    Cai, Yitian; Teo, Boon Heng Dennis; Yeo, Joo Guan; Lu, Jinhua

    2015-09-11

    In infection, complement C1q recognizes pathogen-congregated antibodies and elicits complement activation. Among endogenous ligands, C1q binds to DNA and apoptotic cells, but whether C1q binds to nuclear DNA in apoptotic cells remains to be investigated. With UV irradiation-induced apoptosis, C1q initially bound to peripheral cellular regions in early apoptotic cells. By 6 h, binding concentrated in the nuclei to the nucleolus but not the chromatins. When nucleoli were isolated from non-apoptotic cells, C1q also bound to these structures. In vivo, C1q exists as the C1 complex (C1qC1r2C1s2), and C1q binding to ligands activates the C1r/C1s proteases. Incubation of nucleoli with C1 caused degradation of the nucleolar proteins nucleolin and nucleophosmin 1. This was inhibited by the C1 inhibitor. The nucleoli are abundant with autoantigens. C1q binding and C1r/C1s degradation of nucleolar antigens during cell apoptosis potentially reduces autoimmunity. These findings help us to understand why genetic C1q and C1r/C1s deficiencies cause systemic lupus erythematosus. PMID:26231209

  7. Microbial growth on C1 compounds

    PubMed Central

    Kemp, M. B.; Quayle, J. R.

    1967-01-01

    1. A study has been made of the incorporation of carbon from [14C]formaldehyde and [14C]formate by cultures of Pseudomonas methanica growing on methane. 2. The distribution of radioactivity within the non-volatile constituents of the ethanol-soluble fractions of the cells, after incubation with labelled compounds for periods of up to 1min., has been analysed by chromatography and radioautography. 3. Radioactivity was fixed from [14C]formaldehyde mainly into the phosphates of the sugars, glucose, fructose, sedoheptulose and allulose. 4. Very little radioactivity was fixed from [14C]formate; after 1min. the only products identified were serine and malate. 5. The distribution of radioactivity within the carbon skeleton of glucose, obtained from short-term incubations with [14C]methanol of Pseudomonas methanica growing on methane, has been investigated. At the earliest time of sampling over 70% of the radioactivity was located in C-1; as the time increased the radioactivity spread throughout the molecule. 6. The results have been interpreted in terms of a variant of the pentose phosphate cycle, involving the condensation of formaldehyde with C-1 of ribose 5-phosphate to give allulose phosphate. PMID:6030306

  8. Evaluation of the mandatory construction induction training program in Western Australia: unanticipated consequences.

    PubMed

    Bahn, Susanne; Barratt-Pugh, Llandis

    2012-08-01

    Since January 1, 2007, Government legislation in Western Australia required all workers in construction to complete mandatory safety awareness training before they began work on site. During the implementation of this new legislation there was considerable resistance from the construction sector due to the mandatory nature of the training. The construction industry viewed this as an unnecessary impost as they considered that there was already sufficient safety training delivered through individual company and site inductions. In 2010, we evaluated the new Construction Induction Training (CIT) in the commercial construction sector in Western Australia to find that since 2007 there has been an unanticipated change in support for the mandatory training. The 2010 study shows a shift in the values of the safety culture for the commercial sector of the construction industry. In 2010, the industry not only supports the mandatory CIT, but is very vocal in its request to re-institute the refresher courses that were withdrawn in 2009. Indeed, 79% of respondents claimed there were measurable benefits to their business having their employees complete the CIT, while 96% claimed the CIT assisted in reducing accidents/incidents on their worksites. This 2010 study indicates that in this case, mandatory training has had a positive effect on safety culture change and gradually reduced work-related injury in the industry since 2007 to the present. The paper uses data from two studies conducted in 2006 and 2010 to highlight the unanticipated change in perception of the value of mandatory safety training in the WA construction industry to one which is positive and supportive. PMID:22410166

  9. Indigenous Worldviews in Intercultural Education: Teachers' Construction of Interculturalism in a Bilingual Quechua-Spanish Program

    ERIC Educational Resources Information Center

    Valdiviezo, Laura Alicia

    2010-01-01

    This paper examines teachers' implementation of a bilingual intercultural education (BIE) program in Peru. This program is inspired by global policies that promote cultural pluralism and educational access to marginalized indigenous populations. Broadly addressed in policy in Andean countries, interculturalism in Peru has remained a core…

  10. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., requirements, and standards of the Americans with Disabilities Act Accessibility Guidelines, 36 CFR part 1191. ... NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL COUNTERINTELLIGENCE CENTER § 1807.151 Program...

  11. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., requirements, and standards of the Americans with Disabilities Act Accessibility Guidelines, 36 CFR part 1191. ... NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL COUNTERINTELLIGENCE CENTER § 1807.151 Program...

  12. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., requirements, and standards of the Americans with Disabilities Act Accessibility Guidelines, 36 CFR part 1191. ... NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL COUNTERINTELLIGENCE CENTER § 1807.151 Program...

  13. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., requirements, and standards of the Americans with Disabilities Act Accessibility Guidelines, 36 CFR part 1191. ... NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL COUNTERINTELLIGENCE CENTER § 1807.151 Program...

  14. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., requirements, and standards of the Americans with Disabilities Act Accessibility Guidelines, 36 CFR part 1191. ... NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL COUNTERINTELLIGENCE CENTER § 1807.151 Program...

  15. 40 CFR 63.42 - Program requirements governing construction or reconstruction of major sources.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.42 Program requirements governing... cause by EPA to apply the sanctions and remedies set forth in the Clean Air Act section 502(I). (c... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS...

  16. 40 CFR 63.42 - Program requirements governing construction or reconstruction of major sources.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.42 Program requirements governing... cause by EPA to apply the sanctions and remedies set forth in the Clean Air Act section 502(I). (c... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS...

  17. 40 CFR 63.42 - Program requirements governing construction or reconstruction of major sources.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.42 Program requirements governing... cause by EPA to apply the sanctions and remedies set forth in the Clean Air Act section 502(I). (c... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS...

  18. Evaluating the Facilities Planning, Design, and Construction Department: The Capital Programs Management Audit.

    ERIC Educational Resources Information Center

    Kaiser, Harvey H.; Kirkwood, Dennis M.

    2000-01-01

    Presents a diagnostic model for assessing the state of an institution's capital programs management (CPM) by delineating "work processes" which comprise that function. What capital programs management is, its resources, and its phases and work processes are described, followed by case studies of the CPM Process Model as an assessment tool. (GR)

  19. An Evaluation of the Right Choices Program to Determine Effectiveness in Delivering Constructive Interventions and Providing an Early Support Program in Order to Modify Behavior of First-Time Student Offenders Who Commit Drug and Violent Acts

    ERIC Educational Resources Information Center

    Barnes, Lisa B.

    2010-01-01

    The purpose of the study was to perform a program evaluation of the Right Choices Program to determine the program's effectiveness in delivering constructive interventions that modify student behavior once students have left the program and have returned to their regular learning environment. This mixed-method evaluation consisted of an…

  20. Citizen Oversight of Public School Construction Programs: In Search of Promising Practice.

    ERIC Educational Resources Information Center

    2003

    This paper asserts that one part of a comprehensive control system for school construction projects is a citizen oversight committee. It suggests that citizen oversight committees are a cost-effective and politically important method for supplementing a school board in its monitoring and oversight functions. Inaddition, the committee acts as a…

  1. Predators of Knowledge Construction: Interpreting Students' Metacognition in an Amusement Park Physics Program

    ERIC Educational Resources Information Center

    Anderson, David; Nashon, Samson

    2007-01-01

    It is recognized widely that learning is a dynamic and idiosyncratic process of construction and reconstruction of concepts in response to new experiences. It is influenced by the learner's prior knowledge, motivation, and sociocultural context. This study investigated how year 11 and 12 physics students' metacognition influences the development…

  2. Template Construction as a Basis for Error-Analysis Packages in Language Learning Programs.

    ERIC Educational Resources Information Center

    Helmreich, Stephen C.

    1987-01-01

    An "intelligent" system for constructing computer-assisted pattern drills to be used in second language instruction is proposed. First, some of the difficulties in designing intelligent error analysis are discussed briefly. Two major approaches to error analysis in computer-assisted instruction, pattern matching and parsing, are described, and…

  3. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments...

  4. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments...

  5. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (MAY 2012)...

  6. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (NOV 2009)...

  7. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (JUN 2011)...

  8. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments...

  9. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments...

  10. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a), use the following clause: Balance of Payments...

  11. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (OCT 2013)...

  12. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (AUG 2013)...

  13. 36 CFR 1154.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... construction and alterations. 1154.151 Section 1154.151 Parks, Forests, and Public Property ARCHITECTURAL AND... ACTIVITIES CONDUCTED BY THE ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD § 1154.151...

  14. 36 CFR 1154.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... construction and alterations. 1154.151 Section 1154.151 Parks, Forests, and Public Property ARCHITECTURAL AND... ACTIVITIES CONDUCTED BY THE ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD § 1154.151...

  15. 36 CFR 1154.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... construction and alterations. 1154.151 Section 1154.151 Parks, Forests, and Public Property ARCHITECTURAL AND... ACTIVITIES CONDUCTED BY THE ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD § 1154.151...

  16. 36 CFR 1154.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... construction and alterations. 1154.151 Section 1154.151 Parks, Forests, and Public Property ARCHITECTURAL AND... ACTIVITIES CONDUCTED BY THE ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD § 1154.151...

  17. Mid-Atlantic Regional Training Center for Residential Construction Trades. Final Program Evaluation Report.

    ERIC Educational Resources Information Center

    Wasdyke (R. G.) & Associates, Annapolis, MD.

    A group of partners headed by the Home Builders Institute (HBI) created the Mid-Atlantic Regional Training (MART) Center for Residential Construction, with a primary focus on providing education and training services related to the masonry and carpentry trades at existing institutions in the District of Columbia, Maryland, Virginia, and West…

  18. Facility Programming and Construction Criteria [Planning Guide]. 702 KAR 4:170.

    ERIC Educational Resources Information Center

    Kentucky State Dept. of Education, Frankfort. Div. of Facilities Management.

    This facility construction planning guide presents the minimum instructional space standards for Kentucky's public school system. It provides definitions of terms found in the regulations; presents space requirements for every type of instructional space within a public school, including circulation areas, storage, and mechanical/electrical areas;…

  19. Complete cDNA sequence of human complement C1s and close physical linkage of the homologous genes C1s and C1r

    SciTech Connect

    Tosi, M.; Duponchel, C.; Meo, T.; Julier, C.

    1987-12-29

    Overlapping molecular clones encoding the complement subcomponent C1s were isolated from a human liver cDNA library. The nucleotide sequence reconstructed from these clones spans about 85% of the length of the liver C1s messenger RNAs, which occur in three distinct size classes around 3 kilobases in length. Comparisons with the sequence of C1r, the other enzymatic subcomponent of C1, reveal 40% amino acid identity and conservation of all the cysteine residues. Beside the serine protease domain, the following sequence motifs, previously described in C1r, were also found in C1s: (a) two repeats of the type found in the Ba fragment of complement factor B and in several other complement but also noncomplement proteins, (b) a cysteine-rich segment homologous to the repeats of epidermal growth factor precursor, and (c) a duplicated segment found only in C1r and C1s. Differences in each of these structural motifs provide significant clues for the interpretation of the functional divergence of these interacting serine protease zymogens. Hybridizations of C1r and C1s probes to restriction endonuclease fragments of genomic DNA demonstrate close physical linkage of the corresponding genes. The implications of this finding are discussed with respect to the evolution of C1r and C1s after their origin by tandem gene duplication and to the previously observed combined hereditary deficiencies of Clr and Cls.

  20. A Concept of Constructing a Common Information Space for High Tech Programs Using Information Analytical Systems

    NASA Astrophysics Data System (ADS)

    Zakharova, Alexandra A.; Kolegova, Olga A.; Nekrasova, Maria E.

    2016-04-01

    The paper deals with the issues in program management used for engineering innovative products. The existing project management tools were analyzed. The aim is to develop a decision support system that takes into account the features of program management used for high-tech products: research intensity, a high level of technical risks, unpredictable results due to the impact of various external factors, availability of several implementing agencies. The need for involving experts and using intelligent techniques for information processing is demonstrated. A conceptual model of common information space to support communication between members of the collaboration on high-tech programs has been developed. The structure and objectives of the information analysis system “Geokhod” were formulated with the purpose to implement the conceptual model of common information space in the program “Development and production of new class mining equipment – “Geokhod”.

  1. The Effects of "Girl-Friendly" Schools: Evidence from the BRIGHT School Construction Program in Burkina Faso. NBER Working Paper No. 18115

    ERIC Educational Resources Information Center

    Kazianga, Harounan; Levy, Dan; Linden, Leigh L.; Sloan, Matt

    2012-01-01

    We evaluate the causal effects of a program that constructed high quality "girl-friendly" primary schools in Burkina Faso, using a regression discontinuity design 2.5 years after the program started. We find that the program increased enrollment of all children between the ages of 5 and 12 by 20 percentage points and increased their test scores by…

  2. Department of Education's College Construction Loan Programs. Hearing before a Subcommittee of the Committee on Government Operations. House of Representatives, Ninety-Eighth Congress, Second Session.

    ERIC Educational Resources Information Center

    Congress of the U. S., Washington, DC. House Committee on Government Operations.

    This document records the hearing of a Subcommittee of the House on its 3-month investigation of the College Housing Loan Program and the Academic Facilities Loan Program, which are administered by the Department of Education. These programs have awarded about $5 billion in loans to finance the construction of dormitories, dining halls, student…

  3. Automatic planning and programming for robotic construction of planetary/lunar structures

    SciTech Connect

    Boissiere, P.T.

    1997-04-01

    Many difficult material handling needs exist in remote unstructured environments. Currently these operations are accomplished using personnel in direct contact with the hazards. A safe and cost-effective alternative to this approach is the use of intelligent robotic systems for the excavation, handling, transport and manipulation of materials during remote construction operations. A robotic system designed for these tasks has been developed at Sandia National Laboratories which successfully integrates computer controlled manipulation and mobility to deliver these needed robotic capabilities in remote applications such as planetary operations. The mobile robot, RETRVIR, incorporates advanced developments in the integration of sensors, advanced computing environments, and graphical user interfaces. The addition of these elements in the control of remotely operated equipment have shown great promise for reducing the cost of remote construction while providing faster and safer operations.

  4. C1-inhibitor (C1-INH) autoantibodies in hereditary angioedema. Strong correlation with the severity of disease in C1-INH concentrate naïve patients.

    PubMed

    Varga, Lilian; Széplaki, Gábor; Visy, Beáta; Füst, George; Harmat, George; Miklós, Katalin; Németh, Julianna; Cervenak, László; Karádi, István; Farkas, Henriette

    2007-02-01

    The presence of autoantibodies to C1-inhibitor (C1-INH-Abs) is a hallmark of acquired C1-inhibitor deficiency. However, only scarce data are available on their prevalence in hereditary angioedema (HAE). In a prospective study performed between 2001 and 2004 in 95 patients with Type I or II HAE, serum samples were taken one to three times a year and clinical status of the patients was registered. Serum samples were tested for total activity of the classical pathway, C1q, C3, C4 and C1-inhibitor (C1-INH) concentration and activity levels, as well as the presence of IgG, IgA and IgM type anti-C1-inhibitor antibodies (C1-INH-Ab). Fifty-four healthy age and gender matched persons served as control. Significant differences between the patients and controls in the occurrence of elevated (2S.D. higher than mean of control) C1-INH-Abs titers was found only in the case of IgM type C1-INH-Abs. Elevated (>4.22AU/ml) IgM C1-INH-Abs levels were found in 31 and 4% of the patients and controls, respectively (p<0.001). Surprisingly, high titer IgM C1-INH-Abs were present with equal frequency in the 41 HAE patients ever treated with C1-INH concentrate and in the 54 C1-INH treatment naïve patients. In the latter group, strong positive correlation between the levels of the IgM C1-INH-Abs and the most severe disease (score 1) (p=0.0021) and the yearly attack rate (p=0.0173) were obtained. In addition, the levels of the IgM C1-INH-Abs exhibited strong negative correlation to the C1-inhibitor concentration and functional activity, total classical complement pathway activity, and a positive correlation to total IgM concentration. Taken together, these data indicate that IgM type C1-INH-Abs are present with highly elevated frequency in HAE patients irrespectively of the previous treatment with C1-INH concentrate. Most probable production of these autoantibodies is the consequence of the activation of complement and other plasma enzyme systems during HAE attacks. Determination of IgM C1

  5. Characterization of C1 inhibitor binding to neutrophils.

    PubMed Central

    Chang, N S; Boackle, R J; Leu, R W

    1991-01-01

    In a previous study we have isolated neutrophil membrane proteins that non-covalently bind to native C1-INH (105,000 MW) and a non-functional, degraded C1-INH (88,000 MW; C1-INH-88). To further characterize the binding nature, we have designed a novel kinetic C1 titration assay which enables not only a quantification of the removal of fluid-phase C1-INH by neutrophils, but also a concomitant measure of residual C1-INH function. Native C1-INH, when adsorbed to EDTA-pretreated neutrophils, lost its function in the inhibition of fluid-phase C1. The non-functional C1-INH-88, which is probably devoid of a reactive centre, was found to block the binding of native C1-INH to neutrophils. Pretreatment of neutrophils with serine esterase inhibitors did not abrogate binding capacity of the cells for C1-INH, whereas the binding affinity for C1-INH was lost when the cells were pretreated with trypsin. An array of human peripheral blood leucocytes and several lymphoid cell lines has surface binding sites for C1-INH, but not on human erythrocytes and U937 cells. Binding was further confirmed using (i) C1-INH-microsphere beads to neutrophils, in which the binding was blocked when pretreating neutrophils with excess C1-INH or with trypsin, and (ii) radiolabelled C1-INH to neutrophils, which was competitively blocked by unlabelled non-functional C1-INH-88. Desialylation of C1-INH significantly reduced its binding affinity for neutrophils, indicating that the membrane receptor sites on neutrophils could be specific for the binding of sialic acid residues on C1-INH. Overall, our studies indicate that neutrophils or other leucocytes possess specific surface binding sites for the sialic acid-containing portion of C1-INH. PMID:2045131

  6. Program fullerene: a software package for constructing and analyzing structures of regular fullerenes.

    PubMed

    Schwerdtfeger, Peter; Wirz, Lukas; Avery, James

    2013-06-30

    Fullerene (Version 4.4) is a general purpose open-source program that can generate any fullerene isomer, perform topological and graph theoretical analysis, as well as calculate a number of physical and chemical properties. The program creates symmetric planar drawings of the fullerene graph and generates accurate molecular 3D geometries by way of force-field optimization, serving as a good starting point for further quantum theoretical treatments. It includes a number of fullerene-to-fullerene transformations, such as Goldberg-Coxeter transforms, Stone-Wales transforms, Endo-Kroto, Yoshida-Fowler, and Brinkmann-Fowler vertex insertions. The program is written in standard Fortran and C++ and can easily be installed in a Linux or UNIX environment. PMID:23559399

  7. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public Health... investigators engaged in biomedical research, and to broaden the opportunities for participation in...

  8. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public Health... investigators engaged in biomedical research, and to broaden the opportunities for participation in...

  9. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public Health... investigators engaged in biomedical research, and to broaden the opportunities for participation in...

  10. 12 CFR 794.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... alterations. 794.151 Section 794.151 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE NATIONAL CREDIT UNION ADMINISTRATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL CREDIT UNION ADMINISTRATION §...

  11. 12 CFR 794.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... alterations. 794.151 Section 794.151 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE NATIONAL CREDIT UNION ADMINISTRATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL CREDIT UNION ADMINISTRATION §...

  12. 12 CFR 794.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... alterations. 794.151 Section 794.151 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE NATIONAL CREDIT UNION ADMINISTRATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL CREDIT UNION ADMINISTRATION §...

  13. 12 CFR 794.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... alterations. 794.151 Section 794.151 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE NATIONAL CREDIT UNION ADMINISTRATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL CREDIT UNION ADMINISTRATION §...

  14. 12 CFR 794.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... alterations. 794.151 Section 794.151 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING THE OPERATIONS OF THE NATIONAL CREDIT UNION ADMINISTRATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL CREDIT UNION ADMINISTRATION §...

  15. Constructing Coherence: Structural Predictors of Perceptions of Coherence in NYC Teacher Education Programs

    ERIC Educational Resources Information Center

    Grossman, Pam; Hammerness, Karen M.; McDonald, Morva; Ronfeldt, Matt

    2008-01-01

    In this article, the authors focus on the concept of coherence, a relatively underexplored concept in teacher education. They investigate the relationship between students' perceptions of coherence and a number of structural features of teacher education programs to help develop a stronger definition of one important dimension of coherence--the…

  16. Application of Matrix Outcome Mapping to Constructively Align Program Outcomes and Course Outcomes in Higher Education

    ERIC Educational Resources Information Center

    Mazouz, Abdelkader; Crane, Keenan

    2013-01-01

    Establishing a link between Course Learning Outcomes (LOs) and Program Outcomes (POs) while assessing the course contents and delivery are among the most challenging issues in Higher Education. In the present study two forms were generated based on specific Course Learning Outcomes identified in the syllabus at the beginning of the teaching term:…

  17. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41...

  18. 2005 Mississippi Curriculum Framework: Secondary Building Trades. (Program CIP: 46.0000 - Construction Trades, General)

    ERIC Educational Resources Information Center

    Jernigan, Jarvis; Manning, Phillip; Matkins, Billy

    2005-01-01

    Secondary vocational-technical education programs in Mississippi are faced with many challenges resulting from sweeping educational reforms at the national and state levels. Schools and teachers are increasingly being held accountable for providing true learning activities to every student in the classroom. This accountability is measured through…

  19. 22 CFR 1600.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this... alterations. 1600.151 Section 1600.151 Foreign Relations JAPAN-UNITED STATES FRIENDSHIP COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE...

  20. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION...

  1. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES... Activities Conducted by the U.S. International Trade Commission § 201.151 Program accessibility: New... Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply...

  2. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES... Activities Conducted by the U.S. International Trade Commission § 201.151 Program accessibility: New... Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply...

  3. 22 CFR 530.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... alterations. 530.151 Section 530.151 Foreign Relations BROADCASTING BOARD OF GOVERNORS ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE BROADCASTING BOARD...

  4. 5 CFR 1850.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... handicaps. The definitions, requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section. ... ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE OFFICE...

  5. 22 CFR 1005.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... alterations. 1005.151 Section 1005.151 Foreign Relations INTER-AMERICAN FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE INTER-AMERICAN...

  6. 22 CFR 1005.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... alterations. 1005.151 Section 1005.151 Foreign Relations INTER-AMERICAN FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE INTER-AMERICAN...

  7. 22 CFR 1005.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... alterations. 1005.151 Section 1005.151 Foreign Relations INTER-AMERICAN FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE INTER-AMERICAN...

  8. 22 CFR 1005.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... alterations. 1005.151 Section 1005.151 Foreign Relations INTER-AMERICAN FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE INTER-AMERICAN...

  9. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... MADISON MEMORIAL FELLOWSHIP FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151...

  10. 22 CFR 1510.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section. ... alterations. 1510.151 Section 1510.151 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE AFRICAN DEVELOPMENT...

  11. 22 CFR 1510.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section. ... alterations. 1510.151 Section 1510.151 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE AFRICAN DEVELOPMENT...

  12. 22 CFR 1510.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section. ... alterations. 1510.151 Section 1510.151 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE AFRICAN DEVELOPMENT...

  13. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... MADISON MEMORIAL FELLOWSHIP FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151...

  14. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... MADISON MEMORIAL FELLOWSHIP FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151...

  15. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... MADISON MEMORIAL FELLOWSHIP FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151...

  16. 22 CFR 1510.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section. ... alterations. 1510.151 Section 1510.151 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE AFRICAN DEVELOPMENT...

  17. 22 CFR 1005.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... alterations. 1005.151 Section 1005.151 Foreign Relations INTER-AMERICAN FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE INTER-AMERICAN...

  18. 22 CFR 1510.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... established in 41 CFR 101-19.600 to 101-19.607, apply to buildings covered by this section. ... alterations. 1510.151 Section 1510.151 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE AFRICAN DEVELOPMENT...

  19. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... MADISON MEMORIAL FELLOWSHIP FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151...

  20. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE...

  1. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE...

  2. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE...

  3. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE...

  4. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR... and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE...

  5. An Exploratory Study of the Impact of College Student Leadership Programs upon the Construct of Mindfulness

    ERIC Educational Resources Information Center

    Horowitz, Rich

    2012-01-01

    Mindfulness is a key skill that produces the greater psychological awareness identified by most leadership scholars as being essential to effective leadership. This study conducted an exploratory assessment of the effectiveness of mindfulness-based cocurricular collegiate leadership programs through pre- and post-participation application of the…

  6. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION...

  7. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION...

  8. Green Construction and Energy Training Program for At-Risk Individuals: A Case Study

    ERIC Educational Resources Information Center

    del Puerto, Carla Lopez; Crowson, Adrienne

    2013-01-01

    Training individuals who are at risk of unemployment/underemployment to increase their employability is a mission of many nonprofit agencies. These training programs, often supported by government funding, attempt to reduce these individuals' reliance on government assistance. The purpose of this study is to obtain hard data and an in-depth…

  9. 36 CFR 1154.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to... TRANSPORTATION BARRIERS COMPLIANCE BOARD ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD § 1154.151...

  10. Emergent Entities and Emergent Processes: Constructing Emergence through Multi-Agent Programming.

    ERIC Educational Resources Information Center

    Wilensky, Uri

    The use of programming language was studied in an eighth grade science classroom. The goal of the EMERGE curriculum is to enable students to understand the global patterns that they observe. EMERGE was used in an eighth-grade classroom of 12 students, with a range of abilities (3 had learning disabilities), in 21 sessions over 3 months. For the…

  11. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION...

  12. Construction safety program for the National Ignition Facility Appendix A: Safety Requirements

    SciTech Connect

    Cerruti, S.J.

    1997-01-14

    These rules apply to all LLNL employees, non-LLNL employees (including contract labor, supplemental labor, vendors, personnel matrixed/assigned from other National Laboratories, participating guests, visitors and students) and construction contractors/subcontractors. The General Safety and Health rules shall be used by management to promote accident prevention through indoctrination, safety and health training and on-the-job application. As a condition for contracts award, all contractors and subcontractors and their employees must certify on Form S & H A-1 that they have read and understand, or have been briefed and understand, the National Ignition Facility OCIP Project General Safety Rules.

  13. Degradation of C1-inhibitor by plasmin: implications for the control of inflammatory processes.

    PubMed Central

    Wallace, E. M.; Perkins, S. J.; Sim, R. B.; Willis, A. C.; Feighery, C.; Jackson, J.

    1997-01-01

    BACKGROUND: A correct balance between protease and inhibitor activity is critical in the maintenance of homoeostasis; excessive activation of enzyme pathways is frequently associated with inflammatory disorders. Plasmin is an enzyme ubiquitously activated in inflammatory disorder, and C1-inhibitor (C1-Inh) is a pivotal inhibitor of protease activity, which is particularly important in the regulation of enzyme cascades generated in plasma. The nature of the interaction between plasmin and C1-Inh is poorly understood. MATERIALS AND METHODS: C1-Inh was immunoadsorbed from the plasma of normal individuals (n = 21), from that of patients with systemic lupus erythematosus (n = 18) or adult respiratory distress syndrome (n = 9), and from the plasma and synovial fluid of patients with rheumatoid arthritis (n = 18). As plasmin is a putative enzyme responsible for C1-Inh was examined using SDS-PAGE. In addition, peptides cleaved from C1-Inh by plasmin were isolated and sequenced and the precise cleavage sites determined from the known primary sequence of C1-Inh. Homology models of C1-Inh were then constructed. RESULTS: Increased levels of cleaved and inactivated C1-Inh were found in each of the inflammatory disorders examined. Through SDS-PAGE analysis it was shown that plasmin rapidly degraded C1-Inh in vitro. The pattern of C1-Inh cleavage seen in vivo in patients with inflammatory disorders and that produced in vitro following incubation with plasmin were very similar. Homology models of C1-Inh indicate that the majority of the plasmin cleavage sites are adjacent to the reactive site of the inhibitor. CONCLUSIONS: This study suggests that local C1-Inh degradation by plasmin may be a central and critical event in the loss of protease inhibition during inflammation. These findings have important implications for our understanding of pathogenic mechanisms in inflammation and for the development of more effectively targeted therapeutic regimes. These findings may also explain

  14. AIR: A batch-oriented web program package for construction of supermatrices ready for phylogenomic analyses

    PubMed Central

    Kumar, Surendra; Skjæveland, Åsmund; Orr, Russell JS; Enger, Pål; Ruden, Torgeir; Mevik, Bjørn-Helge; Burki, Fabien; Botnen, Andreas; Shalchian-Tabrizi, Kamran

    2009-01-01

    Background Large multigene sequence alignments have over recent years been increasingly employed for phylogenomic reconstruction of the eukaryote tree of life. Such supermatrices of sequence data are preferred over single gene alignments as they contain vastly more information about ancient sequence characteristics, and are thus more suitable for resolving deeply diverging relationships. However, as alignments are expanded, increasingly numbers of sites with misleading phylogenetic information are also added. Therefore, a major goal in phylogenomic analyses is to maximize the ratio of information to noise; this can be achieved by the reduction of fast evolving sites. Results Here we present a batch-oriented web-based program package, named AIR that allows 1) transformation of several single genes to one multigene alignment, 2) identification of evolutionary rates in multigene alignments and 3) removal of fast evolving sites. These three processes can be done with the programs AIR-Appender, AIR-Identifier, and AIR-Remover (AIR), which can be used independently or in a semi-automated pipeline. AIR produces user-friendly output files with filtered and non-filtered alignments where residues are colored according to their evolutionary rates. Other bioinformatics applications linked to the AIR package are available at the Bioportal , University of Oslo; together these greatly improve the flexibility, efficiency and quality of phylogenomic analyses. Conclusion The AIR program package allows for efficient creation of multigene alignments and better assessment of evolutionary rates in sequence alignments. Removing fast evolving sites with the AIR programs has been employed in several recent phylogenomic analyses resulting in improved phylogenetic resolution and increased statistical support for branching patterns among the early diverging eukaryotes. PMID:19863793

  15. [Constructing an ACP Simulation-Situation Communication Training Program for Patients With Chronic Kidney Disease].

    PubMed

    Chen, Jui-O; Lin, Chiu-Chu

    2016-06-01

    The aging population and changing lifestyles have lead to the increased general risk of chronic kidney disease. Taiwan currently has the highest incidence and prevalence of end-stage renal disease (ESRD) of any country or region in the world. Hemodialysis patients must endure comorbidities and face the uncertainties of death. The best way to achieve a good death is for patients to sign advance care planning (ACP). However, the key factors contributing to low ACP signature rates have been the lack of communication skills and related training among medical staffs. This article explores the dilemma of ACP using an example of chronic kidney disease (CKD) and proposes a theory-based approach to develop a theoretical framework for an ACP simulation-situation communication training program that integrates the simulation situation model, PREPARED model, and scaffolding theory. Readers may use this framework to design ACP simulation-situation communication training programs that conform to their own conditions and then test the effectiveness and feasibility of these programs in clinical settings. PMID:27250964

  16. Constructing a resilience index for the Enhanced Critical Infrastructure Protection Program

    SciTech Connect

    Fisher, R. E.; Bassett, G. W.; Buehring, W. A.; Collins, M. J.; Dickinson, D. C.; Eaton, L. K.; Haffenden, R. A.; Hussar, N. E.; Klett, M. S.; Lawlor, M. A.; Millier, D. J.; Petit, F. D.; Peyton, S. M.; Wallace, K. E.; Whitfield, R. G.; Peerenboom, J P

    2010-10-14

    Following recommendations made in Homeland Security Presidential Directive 7, which established a national policy for the identification and increased protection of critical infrastructure and key resources (CIKR) by Federal departments and agencies, the U.S. Department of Homeland Security (DHS) in 2006 developed the Enhanced Critical Infrastructure Protection (ECIP) program. The ECIP program aimed to provide a closer partnership with state, regional, territorial, local, and tribal authorities in fulfilling the national objective to improve CIKR protection. The program was specifically designed to identify protective measures currently in place in CIKR and to inform facility owners/operators of the benefits of new protective measures. The ECIP program also sought to enhance existing relationships between DHS and owners/operators of CIKR and to build relationships where none existed (DHS 2008; DHS 2009). In 2009, DHS and its protective security advisors (PSAs) began assessing CIKR assets using the ECIP program and ultimately produced individual protective measure and vulnerability values through the protective measure and vulnerability indices (PMI/VI). The PMI/VI assess the protective measures posture of individual facilities at their 'weakest link,' allowing for a detailed analysis of the most vulnerable aspects of the facilities (Schneier 2003), while maintaining the ability to produce an overall protective measures picture. The PMI has six main components (physical security, security management, security force, information sharing, protective measures assessments, and dependencies) and focuses on actions taken by a facility to prevent or deter the occurrence of an incident (Argonne National Laboratory 2009). As CIKR continue to be assessed using the PMI/VI and owners/operators better understand how they can prevent or deter incidents, academic research, practitioner emphasis, and public policy formation have increasingly focused on resilience as a necessary

  17. A trial of a job-specific workers' health surveillance program for construction workers: study protocol

    PubMed Central

    2011-01-01

    Background Dutch construction workers are offered periodic health examinations. This care can be improved by tailoring this workers health surveillance (WHS) to the demands of the job and adjust the preventive actions to the specific health risks of a worker in a particular job. To improve the quality of the WHS for construction workers and stimulate relevant job-specific preventive actions by the occupational physician, we have developed a job-specific WHS. The job-specific WHS consists of modules assessing both physical and psychological requirements. The selected measurement instruments chosen, are based on their appropriateness to measure the workers' capacity and health requirements. They include a questionnaire and biometrical tests, and physical performance tests that measure physical functional capabilities. Furthermore, our job-specific WHS provides occupational physicians with a protocol to increase the worker-behavioural effectiveness of their counselling and to stimulate job-specific preventive actions. The objective of this paper is to describe and clarify our study to evaluate the behavioural effects of this job-specific WHS on workers and occupational physicians. Methods/Design The ongoing study of bricklayers and supervisors is a nonrandomised trial to compare the outcome of an intervention (job-specific WHS) group (n = 206) with that of a control (WHS) group (n = 206). The study includes a three-month follow-up. The primary outcome measure is the proportion of participants who have undertaken one or more of the preventive actions advised by their occupational physician in the three months after attending the WHS. A process evaluation will be carried out to determine context, reach, dose delivered, dose received, fidelity, and satisfaction. The present study is in accordance with the TREND Statement. Discussion This study will allow an evaluation of the behaviour of both the workers and occupational physician regarding the preventive actions

  18. Molecular analysis of the maize anthocyanin regulatory locus C1.

    PubMed Central

    Cone, K C; Burr, F A; Burr, B

    1986-01-01

    The C1 gene of maize plays a regulatory role in the production of anthocyanin pigments in the aleurone layer of the endosperm. As an initial step toward understanding the molecular details of how C1 controls pigment biosynthesis, we cloned the C1 gene. This was accomplished by first cloning a mutable allele of C1, c1-m5, which contains the transposable element Spm. A combination of molecular and genetic analysis was used to identify the Spm at the C1 locus. Individual genomic DNAs from a population in which the c1-mutable phenotype was segregating with the recessive c1 phenotype were digested with methyl-sensitive restriction enzymes and probed with a small DNA fragment derived from a defective Spm. One Sal I restriction fragment complementary to the Spm probe was shown to be present in the DNA of individuals with the c1-m5 phenotype but absent from DNA of individuals with a recessive c1 phenotype. Subsequent cloning and restriction analysis of this fragment revealed sequences flanking the Spm that proved to be C1-specific. A DNA fragment derived from the flanking sequences was then used as a probe to clone the wild-type C1 gene and several additional alleles of C1, including one stable recessive, two mutations caused by Ds insertions, one mutation induced by insertion of a defective Spm, and two dominant mutations, C1-S and C1-I. RNA blot hybridization analysis of three C1 alleles indicates that C1 regulation of the Bz1 and A1 structural genes in the anthocyanin biosynthetic pathway is at the transcriptional level. Images PMID:3025847

  19. Nash equilibrium in differential games and the construction of the programmed iteration method

    SciTech Connect

    Averboukh, Yurii V

    2011-05-31

    This work is devoted to the study of nonzero-sum differential games. The set of payoffs in a situation of Nash equilibrium is examined. It is shown that the set of payoffs in a situation of Nash equilibrium coincides with the set of values of consistent functions which are fixed points of the program absorption operator. A condition for functions to be consistent is given in terms of the weak invariance of the graph of the functions under a certain differential inclusion. Bibliography: 18 titles.

  20. Interaction between complement subcomponent C1q and bacterial lipopolysaccharides.

    PubMed

    Zohair, A; Chesne, S; Wade, R H; Colomb, M G

    1989-02-01

    The heptose-less mutant of Escherichia coli, D31m4, bound complement subcomponent C1q and its collagen-like fragments (C1qCLF) with Ka values of 1.4 x 10(8) and 2.0 x 10(8) M-1 respectively. This binding was suppressed by chemical modification of C1q and C1qCLF using diethyl pyrocarbonate (DEPC). To investigate the role of lipopolysaccharides (LPS) in this binding, biosynthetically labelled [14C]LPS were purified from E. coli D31m4 and incorporated into liposomes prepared from phosphatidylcholine (PC) and phosphatidylethanolamine (PE) [PC/PE/LPS, 2:2:1, by wt.]. Binding of C1q or its collagen-like fragments to the liposomes was estimated via a flotation test. These liposomes bound C1q and C1qCLF with Ka values of 8.0 x 10(7) and 2.0 x 10(7) M-1; this binding was totally inhibited after chemical modification of C1q and C1qCLF by DEPC. Liposomes containing LPS purified from the wild-strain E. coli K-12 S also bound C1q and C1qCLF, whereas direct binding of C1q or C1qCLF to the bacteria was negligible. Diamines at concentrations which dissociate C1 into C1q and (C1r, C1s)2, strongly inhibited the interaction of C1q or C1qCLF with LPS. Removal of 3-deoxy-D-manno-octulosonic acid (2-keto-3-deoxyoctonic acid; KDO) from E. coli D31m4 LPS decreases the binding of C1qCLF to the bacteria by 65%. When this purified and modified LPS was incorporated into liposomes, the C1qCLF binding was completely abolished. These results show: (i) the essential role of the collagen-like moiety and probably its histidine residues in the interaction between C1q and the mutant D31m4; (ii) the contribution of LPS, particularly the anionic charges of KDO, to this interaction. PMID:2649081

  1. 26 CFR 1.1092(c)-1 - Qualified covered calls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Qualified covered calls. 1.1092(c)-1 Section 1.1092(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Wash Sales of Stock Or Securities § 1.1092(c)-1 Qualified covered calls. (a)...

  2. 26 CFR 49.4262(c)-1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 16 2010-04-01 2010-04-01 true Definitions. 49.4262(c)-1 Section 49.4262(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) MISCELLANEOUS EXCISE TAXES FACILITIES AND SERVICES EXCISE TAXES Transportation of Persons § 49.4262(c)-1 Definitions. (a) The continental United States. For purposes...

  3. 26 CFR 31.3401(c)-1 - Employee.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Employee. 31.3401(c)-1 Section 31.3401(c)-1... Income Tax at Source § 31.3401(c)-1 Employee. (a) The term employee includes every individual performing... relationship of employer and employee. The term includes officers and employees, whether elected or...

  4. 26 CFR 1.1092(c)-1 - Qualified covered calls.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 11 2012-04-01 2012-04-01 false Qualified covered calls. 1.1092(c)-1 Section 1.1092(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Wash Sales of Stock Or Securities § 1.1092(c)-1 Qualified covered...

  5. A linear semi-infinite programming strategy for constructing optimal wavelet transforms in multivariate calibration problems.

    PubMed

    Coelho, Clarimar José; Galvão, Roberto K H; de Araújo, Mário César U; Pimentel, Maria Fernanda; da Silva, Edvan Cirino

    2003-01-01

    A novel strategy for the optimization of wavelet transforms with respect to the statistics of the data set in multivariate calibration problems is proposed. The optimization follows a linear semi-infinite programming formulation, which does not display local maxima problems and can be reproducibly solved with modest computational effort. After the optimization, a variable selection algorithm is employed to choose a subset of wavelet coefficients with minimal collinearity. The selection allows the building of a calibration model by direct multiple linear regression on the wavelet coefficients. In an illustrative application involving the simultaneous determination of Mn, Mo, Cr, Ni, and Fe in steel samples by ICP-AES, the proposed strategy yielded more accurate predictions than PCR, PLS, and nonoptimized wavelet regression. PMID:12767151

  6. Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: structure of the active catalytic region of C1r.

    PubMed

    Kardos, József; Harmat, Veronika; Palló, Anna; Barabás, Orsolya; Szilágyi, Katalin; Gráf, László; Náray-Szabó, Gábor; Goto, Yuji; Závodszky, Péter; Gál, Péter

    2008-03-01

    C1r is a modular serine protease which is the autoactivating component of the C1 complex of the classical pathway of the complement system. We have determined the first crystal structure of the entire active catalytic region of human C1r. This fragment contains the C-terminal serine protease (SP) domain and the preceding two complement control protein (CCP) modules. The activated CCP1-CCP2-SP fragment makes up a dimer in a head-to-tail fashion similarly to the previously characterized zymogen. The present structure shows an increased number of stabilizing interactions. Moreover, in the crystal lattice there is an enzyme-product relationship between the C1r molecules of neighboring dimers. This enzyme-product complex exhibits the crucial S1-P1 salt bridge between Asp631 and Arg446 residues, and intermolecular interaction between the CCP2 module and the SP domain. Based on these novel structural information we propose a new split-and-reassembly model for the autoactivation of the C1r. This model is consistent with experimental results that have not been explained adequately by previous models. It allows autoactivation of C1r without large-scale, directed movement of C1q arms. The model is concordant with the stability of the C1 complex during activation of the next complement components. PMID:17996945

  7. Shuttle Rocket Motor Program: NASA should delay awarding some construction contracts. Report to the Chair, Subcommittee on Government Activities and Transportation, Committee on Government Operations, House of Representatives

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Even though the executive branch has proposed terminating the Advanced Solid Rocket Motor (ASRM) program, NASA is proceeding with all construction activity planned for FY 1992 to avoid schedule slippage if the program is reinstated by Congress. However, NASA could delay some construction activities for at least a few months without affecting the current launch data schedule. For example, NASA could delay Yellow Creek's motor storage and dock projects, Stennis' dock project, and Kennedy's rotation processing and surge facility and dock projects. Starting all construction activities as originally planned could result in unnecessarily incurring additional costs and termination liability if the funding for FY 1993 is not provided. If Congress decides to continue the program, construction could still be completed in time to avoid schedule slippage.

  8. Installation restoration program, construction report for interim remedial action and treatability study for Indian Mountain Long Range Radar Station, Alaska. Final report, 1 August-8 December 1995

    SciTech Connect

    1995-12-13

    During the summer of 1995, two construction tasks were conducted at Indian Mountain Long Range Radar Station (LRRS). This work was completed under the U.S. Air Force (Air Force) Installation Restoration Program (IRP). The construction tasks included excavation of a water diversion ditch as an interim remedial action (IRA). Also, a biotreatment cell was constructed to conduct a treatability study of contaminated soils excavated during 1994 sampling activities. This report describes the completion of these two construction tasks, analytical results from associate soil and water sampling, and conclusions based on observations and sampling results.

  9. Constructing vulnerabilty and protective measures indices for the enhanced critical infrastructure protection program.

    SciTech Connect

    Fisher, R. E.; Buehring, W. A.; Whitfield, R. G.; Bassett, G. W.; Dickinson, D. C.; Haffenden, R. A.; Klett, M. S.; Lawlor, M. A.; Decision and Information Sciences; LANL

    2009-10-14

    The US Department of Homeland Security (DHS) has directed its Protective Security Advisors (PSAs) to form partnerships with the owners and operators of assets most essential to the Nation's well being - a subclass of critical infrastructure and key resources (CIKR) - and to conduct site visits for these and other high-risk assets as part of the Enhanced Critical Infrastructure Protection (ECIP) Program. During each such visit, the PSA documents information about the facility's current CIKR protection posture and overall security awareness. The primary goals for ECIP site visits (DHS 2009) are to: (1) inform facility owners and operators of the importance of their facilities as an identified high-priority CIKR and the need to be vigilant in light of the ever-present threat of terrorism; (2) identify protective measures currently in place at these facilities, provide comparisons of CIKR protection postures across like assets, and track the implementation of new protective measures; and (3) enhance existing relationships among facility owners and operators; DHS; and various Federal, State, local tribal, and territorial partners. PSAs conduct ECIP visits to assess overall site security; educate facility owners and operators about security; help owners and operators identify gaps and potential improvements; and promote communication and information sharing among facility owners and operators, DHS, State governments, and other security partners. Information collected during ECIP visits is used to develop metrics; conduct sector-by-sector and cross-sector vulnerability comparisons; identify security gaps and trends across CIKR sectors and subsectors; establish sector baseline security survey results; and track progress toward improving CIKR security through activities, programs, outreach, and training (Snyder 2009). The data being collected are used in a framework consistent with the National Infrastructure Protection Plan (NIPP) risk criteria (DHS 2009). The NIPP

  10. Programming Constructs for Exascale Computing in Support of Space Situational Awareness

    NASA Astrophysics Data System (ADS)

    Schmalz, M.; Ranka, S.; Hayden, E.; Chapman, W.; Sahni, S.; Ritter, G.

    2013-09-01

    Increasing image and signal data burden associated with astronomical image processing in support of space situational awareness implies much-needed growth of computational throughput beyond petascale (1015 FLOP/s) to exascale regimes (1018 FLOP/s, 1018 bytes of memory, 1018 disks and Input/Output (I/O) channels, etc.) In addition to growth in applications data burden and diversity, the breadth and diversity of high performance computing architectures and their various organizations have confounded the development of a single, unifying, practicable model of parallel computation. Therefore, models for parallel Exa Scale processing have leveraged architectural and structural idiosyncrasies, yielding potential misapplications. In response to this challenge, we have developed a concise, efficient computational paradigm and software called Parallel Computing with Exascale Mapping (PCEM) to facilitate efficient mapping of annotated application codes to parallel exascale processors. Our theory, algorithms, software, and experimental results support annotation-based parallelization of application codes for envisioned exascale architectures, based on Image Algebra (IA) [Rit01]. Because of the rigor, completeness, conciseness, and layered design of image algebra notation, application-to-architecture mapping is feasible and scalable for exascale architectures. In particular, parallel operations and programs can be categorized in terms of six types of parallel operations - each type is mapped to heterogeneous exascale processors via simple rules in the PCEM annotation language. In this paper, we overview the opportunities and challenges of exascale computing for image and signal computing in support of astronomical image processing in space situational awareness applications. We discuss software interfaces and several demonstration applications, with performance analysis and results in terms of execution time as well as storage, power, and energy consumption for bus

  11. Transcriptional activator elements for curtovirus C1 expression reside in the 3' coding region of ORF C1.

    PubMed

    Hur, Jingyung; Buckley, Kenneth; Lee, Sukchan; Davis, Keith

    2007-02-28

    Beet curly top virus (BCTV) and Beet severe curly top virus (BSCTV), members of curtoviruses, encode seven open reading frames (ORFs) within a approximately 3 kb genome. One of these viral ORFs, C1, is known to play an important role in the early stage of viral infection in plants during initiation of viral DNA replication. We used promoter:: reporter (beta-glucuronidase) gene fusions in transgenic Ara-bidopsis to identify the putative promoter region of BCTV ORF C1. Unlike other geminiviruses, the intergenic region of BCTV was not sufficient to promote C1 expression in transgenic plants. When sequences extending into the coding region of C1 were tested, strong expression of the reporter protein was observed in vascular tissues of transgenic plants. This expression was not dependent on the presence of the intergenic regions or proximal 5' portions of the C1 coding region. Transgenic plants expressing a reporter gene under control of the putative complete C1 promoter were inoculated with virus to determine if any viral transcript affected C1 expression. Virus inoculated plants did not show any altered pattern or change in of reporter gene expression level. These results suggest that (1) important transcriptional activator elements for C1 expression reside in the 3' portion of C1 coding area itself, (2) C1 protein does not auto-regulate its own expression and (3) C1 expression of two curtoviruses is controlled differently compared to other geminiviruses. PMID:17464215

  12. Platelet C1- inhibitor. A secreted alpha-granule protein.

    PubMed Central

    Schmaier, A H; Smith, P M; Colman, R W

    1985-01-01

    In order to characterize which proteins of the contact phase of coagulation interact with platelets, human platelets were studied immunochemically and functionally to determine if they contain C1- inhibitor. By means of monospecific antibody to C1- inhibitor, a competitive enzyme-linked immunosorbent assay (CELISA) was developed to measure directly platelet C1- inhibitor. With the CELISA, from 33 to 115 ng of C1- inhibitor antigen per 10(8) platelets from 15 normal donors was quantified in lysates of washed human platelets solubilized in nonionic detergent. The mean concentration in 10(8) platelets was 62 +/- 33 ng (SD). Plasma C1- inhibitor either in the platelet suspension medium or on the surface of the platelets could account for only from 6.5 to 16% of the total antigen measured in the solubilized platelets. Upon functional studies, platelets contained 84 +/- 36 ng (SD) of C1- inhibitor activity in 10(8) platelets. As assessed by the CELISA, platelet C1- inhibitor antigen was immunochemically identical to plasma and purified C1- inhibitor. In contrast, the mean concentration of platelet C1- inhibitor antigen in platelets from four patients with classical hereditary angioedema was 8.3 ng/10(8) platelets (range, 5.3 to 11.3 ng/10(8) platelets). 25 and 31% of the total platelet C1- inhibitor was secreted without cell lysis from normal platelets after exposure to collagen (20 micrograms/ml) and thrombin (1 U/ml), respectively, and this secretion was blocked by metabolic inhibitors. Platelet subcellular fractionation showed that platelet C1- inhibitor resided mostly in alpha-granules, similar to the location of platelet fibrinogen. Thus, human platelets contained C1- inhibitor, which became available by platelet secretion. The identification of platelet C1- inhibitor suggests that platelets may modulate the activation of the proteins of early blood coagulation and the classical complement pathways. Images PMID:3965505

  13. CpG mutations in the reactive site of human C1 inhibitor.

    PubMed

    Skriver, K; Radziejewska, E; Silbermann, J A; Donaldson, V H; Bock, S C

    1989-02-25

    C1 inhibitor plays an important role in the regulation of vascular permeability through its ability to inactivate enzymes which release polypeptide kinins. Dysfunctional C1 inhibitor molecules are present in the plasma of affected members of the Da and Ri hereditary angioneurotic edema kindreds. We constructed genomic libraries from Da and Ri patient DNAs which had been cleaved with BclI to generate a fragment containing 21 kilobases of the C1 inhibitor locus. C1 inhibitor gene-containing recombinants originating from mutant Da and Ri alleles were differentiated from those derived from normal alleles by linkage analysis using the intragenic HgiAI restriction fragment length polymorphism. Nucleotide sequencing of the complete protein-coding regions of the mutant alleles identified two different mutations in a CpG dinucleotide corresponding to the first two bases of arginine codon 444. These single base mutations changed the identity of the functionally critical P1 reactive site residue from arginine to cysteine (Da) or histidine (Ri). The additional cysteine residue in C1 inhibitor Da suggests how it is covalently bound to albumin in plasma. The presence of CpG dinucleotides in the codons specifying the P1 arginines of C1 inhibitor and antithrombin III explains the high incidence of histidine and cysteine substitutions observed among dysfunctional mutants of these serine protease inhibitors. PMID:2563376

  14. Fundamental role of C1q in autoimmunity and inflammation

    PubMed Central

    Son, Myoungsun; Santiago-Schwarz, Frances

    2016-01-01

    C1q, historically viewed as the initiating component of the classical complement pathway, also exhibits a variety of complement-independent activities in both innate and acquired immunity. Recent studies focusing on C1q’s suppressive role in the immune system have provided new insight into how abnormal C1q expression and bioactivity may contribute to autoimmunity. In particular, molecular networks involving C1q interactions with cell surface receptors and other ligands are emerging as mechanisms involved in C1q’s modulation of immunity. Here, we discuss the role of C1q in controlling immune cell function, including recently elucidated mechanisms of action, and suggest how these processes are critical for maintaining tissue homeostasis under steady-state conditions and in preventing autoimmunity. PMID:26410546

  15. Hereditary angioedema with normal C1-INH (HAE type III).

    PubMed

    Riedl, Marc A

    2013-01-01

    Hereditary angioedema (HAE) with normal C1 inhibitor (C1-INH), also known as HAE type III, is a familial condition only clinically recognized within the past three decades. Similar to HAE from C1-INH deficiency (HAE types I and II), affected individuals experience unpredictable angioedema episodes of the skin, gastrointestinal tract, and airway. Unique clinical features of HAE with normal C1-INH include the predominance of affected women, frequent exacerbation by estrogen, and a prominence of angioedema that involves the face and oropharynx. The underlying pathophysiology of HAE with normal C1-INH is poorly understood, but indirect evidence points to contact pathway dysregulation with bradykinin-mediated angioedema. Currently, evaluation is complicated by a lack of confirmatory laboratory testing such that clinical criteria must often be used to make the diagnosis of HAE with normal C1-INH. Factor XII mutations have been identified in only a minority of persons affected by HAE with normal C1-INH, limiting the utility of such analysis. To date, no controlled clinical studies have examined the efficacy of therapeutic agents for HAE with normal C1-INH, although published evidence supports frequent clinical benefit with medications shown effective in HAE due to C1-INH deficiency. PMID:24565612

  16. 26 CFR 1.661(c)-1 - Limitation on deduction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Limitation on deduction. 1.661(c)-1 Section 1... Corpus § 1.661(c)-1 Limitation on deduction. An estate or trust is not allowed a deduction under section..., a trust, which reports on the calendar year basis, has distributable net income of $20,000, which...

  17. 26 CFR 31.6413(c)-1 - Special refunds.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 15 2011-04-01 2011-04-01 false Special refunds. 31.6413(c)-1 Section 31.6413(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) EMPLOYMENT TAXES... Administrative Provisions of Special Application to Employment Taxes (Selected Provisions of Subtitle F,...

  18. 26 CFR 1.652(c)-1 - Different taxable years.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Different taxable years. 1.652(c)-1 Section 1... (CONTINUED) INCOME TAXES Trusts Which Distribute Current Income Only § 1.652(c)-1 Different taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable...

  19. 26 CFR 1.662(c)-1 - Different taxable years.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Different taxable years. 1.662(c)-1 Section 1... Corpus § 1.662(c)-1 Different taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year of an estate or trust, the amount he is required to include...

  20. Anti-C1q in systemic lupus erythematosus.

    PubMed

    Stojan, G; Petri, M

    2016-07-01

    C1q is the first component of the classical complement pathway. Both clinically validated in-house ELISA assays as well as commercial ELISA kits are used for detection of anti-C1q antibodies. Anti-C1q autoantibodies can be detected in a wide range of autoimmune diseases and are highly sensitive for hypocomplementemic uticarial vasculitis. In SLE, anti-C1q are strongly associated with proliferative lupus nephritis, and their absence carries a negative predictive value for development of lupus nephritis of close to 100%. Anti-C1q in combination with anti-dsDNA and low complement has the strongest serological association with renal involvement. The anti-C1q titers correlate with global disease activity scores in patients with renal involvement, and higher titers seem to precede renal flares. After the successful treatment of a renal flare, anti-C1q has the tendency to decrease or even become undetectable. The main obstacle to the inclusion of anti-C1q in the classification criteria and clinical management of SLE is the lack of standardized laboratory assays. PMID:27252264

  1. 17 CFR 240.14c-1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Definitions. 240.14c-1 Section 240.14c-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL... Exchange Act of 1934 Regulation 14c: Distribution of Information Pursuant to Section 14(c) §...

  2. 17 CFR 240.14c-1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Definitions. 240.14c-1 Section 240.14c-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL... Exchange Act of 1934 Regulation 14c: Distribution of Information Pursuant to Section 14(c) §...

  3. 17 CFR 240.14c-1 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Definitions. 240.14c-1 Section 240.14c-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL... Exchange Act of 1934 Regulation 14c: Distribution of Information Pursuant to Section 14(c) §...

  4. 17 CFR 240.14c-1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Definitions. 240.14c-1 Section 240.14c-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL... Exchange Act of 1934 Regulation 14c: Distribution of Information Pursuant to Section 14(c) §...

  5. 17 CFR 240.14c-1 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Definitions. 240.14c-1 Section 240.14c-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL... Exchange Act of 1934 Regulation 14c: Distribution of Information Pursuant to Section 14(c) §...

  6. 26 CFR 1.662(c)-1 - Different taxable years.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Different taxable years. 1.662(c)-1 Section 1... Corpus § 1.662(c)-1 Different taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year of an estate or trust, the amount he is required to include...

  7. 26 CFR 1.662(c)-1 - Different taxable years.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Different taxable years. 1.662(c)-1 Section 1... Corpus § 1.662(c)-1 Different taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year of an estate or trust, the amount he is required to include...

  8. Self-Help Construction of 1-Story Buildings. Appropriate Technologies for Development. Program & Training Journal Manual Series, Number 6.

    ERIC Educational Resources Information Center

    Gallant, Peter

    This manual is designed to assist Peace Corps field workers who have little or no construction experience in helping communities or families to construct one-story buildings. Discussed in a chapter on basic planning and design are site and position; size, shape, and floor plan; and construction materials. The next chapter is a detailed examination…

  9. C 1 natural element method for strain gradient linear elasticity and its application to microstructures

    NASA Astrophysics Data System (ADS)

    Nie, Zhi-Feng; Zhou, Shen-Jie; Han, Ru-Jun; Xiao, Lin-Jing; Wang, Kai

    2012-02-01

    C 1 natural element method ( C 1 NEM) is applied to strain gradient linear elasticity, and size effects on microstructures are analyzed. The shape functions in C 1 NEM are built upon the natural neighbor interpolation (NNI), with interpolation realized to nodal function and nodal gradient values, so that the essential boundary conditions (EBCs) can be imposed directly in a Galerkin scheme for partial differential equations (PDEs). In the present paper, C 1 NEM for strain gradient linear elasticity is constructed, and several typical examples which have analytical solutions are presented to illustrate the effectiveness of the constructed method. In its application to microstructures, the size effects of bending stiffness and stress concentration factor (SCF) are studied for microspeciem and microgripper, respectively. It is observed that the size effects become rather strong when the width of spring for microgripper, the radius of circular perforation and the long axis of elliptical perforation for microspeciem come close to the material characteristic length scales. For the U-shaped notch, the size effects decline obviously with increasing notch radius, and decline mildly with increasing length of notch.

  10. The South Carolina Program for Library Development, 1987-1990 under the Library Services and Construction Act (P.L. 98-480, FY 1988).

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    Prepared as an outline of the long-range South Carolina Library development program required by the Library Services and Construction Act (LSCA), this document describes: (1) the library public, with emphasis on the disadvantaged, illiterate, blind and physically handicapped, persons with limited English speaking ability, the elderly, and the…

  11. Engagement in a Community of Learners as a Mediating Agent toward the Construction of Technological Pedagogical Content Knowledge (TPACK) in an Online Master's Program

    ERIC Educational Resources Information Center

    Gillow-Wiles, Henry

    2012-01-01

    This study investigates how teachers develop and extend their understanding and knowledge of teaching and learning with digital technologies in a primarily online Master of Science program. The investigation focuses on exploring the relationship between developing an online community of learners and the construction of technological pedagogical…

  12. Report to the Board of Regents State University System of Florida. Review of Programs: Architecture, Architectural Technology, Landscape Architecture, Interior Design, Construction and Construction Technology, Building Construction, Urban and Regional Planning.

    ERIC Educational Resources Information Center

    McMinn, William G.

    An evaluation and report was done on the status of programs in architecture and related fields in the Florida State University System as a follow-up to a 1983 evaluation. The evaluation involved self-studies prepared by each program and a series of site visits to each of seven campuses and two centers with programs under review. These institutions…

  13. Treatment of type I and II hereditary angioedema with Rhucin, a recombinant human C1 inhibitor.

    PubMed

    Varga, Lilian; Farkas, Henriette

    2008-11-01

    Hereditary and acquired angioedema are of outstanding clinical importance, as edematous attacks associated with these conditions can thrust afflicted patients into mortal danger. Currently, C1 inhibitor concentrate - a human blood product - is available as a replacement therapy. In view of the limited number of donors, as well as the risk of transmission of blood-borne infections, it is a reasonable expectation to develop a therapeutic alternative based on recombinant technology, which would eliminate all these shortcomings. Pharming (Leiden, The Netherlands) has developed Rhucin, a recombinant human C1 inhibitor, as a proprietary product, which is currently being evaluated in Phase III clinical trials. Ongoing studies conducted within the framework of the development program are almost complete and their interim findings are reassuring. This should facilitate successful regulatory approval in the near future, which is indispensable in order to make Rhucin available for patients with hereditary angioedema or other disorders amenable to C1 inhibitor replacement. PMID:20477114

  14. Vein formation in the C1 carbonaceous chondrites

    NASA Technical Reports Server (NTRS)

    Richardson, S. M.

    1978-01-01

    Veins in the C1 chondrites Orgueil, Alais, and Ivuna have been deposited during an extended period of impact brecciation and leaching. At least three generations of mineralization, dominated successively by carbonates, calcium sulfate, and magnesium sulfate, can be recognized. Vein minerals are derived locally by closed-system reactions between matrix phyllosilicates and an aqueous fluid, with the result that few, if any, primitive mineral phases still exist in the C1s.

  15. 26 CFR 1.1402(c)-1 - Trade or business.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...)-7, inclusive, the term “trade or business”, for the purpose of the tax on self-employment income... 26 Internal Revenue 12 2010-04-01 2010-04-01 false Trade or business. 1.1402(c)-1 Section 1.1402(c... (CONTINUED) INCOME TAXES Tax on Self-Employment Income § 1.1402(c)-1 Trade or business. In order for...

  16. 26 CFR 1.1402(c)-1 - Trade or business.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 12 2013-04-01 2013-04-01 false Trade or business. 1.1402(c)-1 Section 1.1402(c... (CONTINUED) INCOME TAXES (CONTINUED) Tax on Self-Employment Income § 1.1402(c)-1 Trade or business. In order for an individual to have net earnings from self-employment, he must carry on a trade or...

  17. 26 CFR 1.1402(c)-1 - Trade or business.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 12 2014-04-01 2014-04-01 false Trade or business. 1.1402(c)-1 Section 1.1402(c... (CONTINUED) INCOME TAXES (CONTINUED) Tax on Self-Employment Income § 1.1402(c)-1 Trade or business. In order for an individual to have net earnings from self-employment, he must carry on a trade or...

  18. 26 CFR 1.1402(c)-1 - Trade or business.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 12 2011-04-01 2011-04-01 false Trade or business. 1.1402(c)-1 Section 1.1402(c... (CONTINUED) INCOME TAXES (CONTINUED) Tax on Self-Employment Income § 1.1402(c)-1 Trade or business. In order for an individual to have net earnings from self-employment, he must carry on a trade or...

  19. 26 CFR 1.1402(c)-1 - Trade or business.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 12 2012-04-01 2012-04-01 false Trade or business. 1.1402(c)-1 Section 1.1402(c... (CONTINUED) INCOME TAXES (CONTINUED) Tax on Self-Employment Income § 1.1402(c)-1 Trade or business. In order for an individual to have net earnings from self-employment, he must carry on a trade or...

  20. Influence of C1-inhibitor on inflammation, edema and shock.

    PubMed

    Dickneite, G

    1993-12-01

    C1-Inhibitor (Berinert, C1 INH), a 104 kDa protein, inhibits complement components (C1 esterase) as well as enzymes of the contact phase of coagulation (Factor XII, Factor XI) and kallikrein, thus regulating kinin generation. C1 INH is used for the treatment of the hereditary angioneurotic edema. This paper will give a survey about the evidence in recent literature concerning the potential efficacy of the compound on other diseases associated with shock, capillary leakage and inflammation as well. In our own experiments we evaluated whether the compound could influence acute inflammatory reactions or the severe systemic inflammatory response syndrome (SIRS) as a consequence of an experimental septic shock. To prevent the sepsis-induced DIC we co-infused the thrombin inhibitors AT III or rec. hirudin in combination with C1 INH. Coinfusion of C1-inhibitor (50-200 U/kg x h) with either rec. hirudin or AT III significantly improved survival rate compared to thrombin inhibitor alone. PMID:8172580

  1. Participatory Training to Improve Safety and Health in Small Construction Sites in Some Countries in Asia: Development and Application of the WISCON Training Program.

    PubMed

    Kawakami, Tsuyoshi

    2016-08-01

    A participatory training program, Work Improvement in Small Construction Sites, was developed to provide practical support measures to the small construction sector. Managers and workers from selected small sites were interviewed about their occupational safety and health risks. The Work Improvement in Small Construction Sites training program comprised a 45-item action checklist, photos, and illustrations showing local examples and group work methods. Pilot training workshops were carried out with workers and employers in Cambodia, Laos, Mongolia, Thailand, and Vietnam. Participants subsequently planned, and using locally available low-cost materials, implemented their own improvements such as hand-made hand trucks to carry heavy materials, removal of projecting nails from timber materials, and fences to protect roof workers from falling. Local Work Improvement in Small Construction Sites trainers consisting of government officials, workers, employers, and nongovernment organization representatives were then trained to implement the Work Improvement in Small Construction Sites training widely. Keys to success were easy-to-apply training tools aiming at immediate, low-cost improvements, and collaboration with various local people's networks. PMID:27296976

  2. Project Build: Integrating Technical and Employability Skills in a Construction Industry-Based Welfare-to-Work Training Program.

    ERIC Educational Resources Information Center

    Overtoom, Christine G.

    Project Build is an eight-week course in construction industry basics for unemployed residents of the neighborhoods surrounding The Ohio State University. Developing curriculum for Project Build revealed that existing training materials in the construction industry focus on technical skills. Extensive conversations with industry experts about…

  3. Mapping Surface Accessibility of the C1r/C1s Tetramer by Chemical Modification and Mass Spectrometry Provides New Insights into Assembly of the Human C1 Complex*

    PubMed Central

    Brier, Sébastien; Pflieger, Delphine; Le Mignon, Maxime; Bally, Isabelle; Gaboriaud, Christine; Arlaud, Gérard J.; Daniel, Régis

    2010-01-01

    C1, the complex that triggers the classic pathway of complement, is a 790-kDa assembly resulting from association of a recognition protein C1q with a Ca2+-dependent tetramer comprising two copies of the proteases C1r and C1s. Early structural investigations have shown that the extended C1s-C1r-C1r-C1s tetramer folds into a compact conformation in C1. Recent site-directed mutagenesis studies have identified the C1q-binding sites in C1r and C1s and led to a three-dimensional model of the C1 complex (Bally, I., Rossi, V., Lunardi, T., Thielens, N. M., Gaboriaud, C., and Arlaud, G. J. (2009) J. Biol. Chem. 284, 19340–19348). In this study, we have used a mass spectrometry-based strategy involving a label-free semi-quantitative analysis of protein samples to gain new structural insights into C1 assembly. Using a stable chemical modification, we have compared the accessibility of the lysine residues in the isolated tetramer and in C1. The labeling data account for 51 of the 73 lysine residues of C1r and C1s. They strongly support the hypothesis that both C1s CUB1-EGF-CUB2 interaction domains, which are distant in the free tetramer, associate with each other in the C1 complex. This analysis also provides the first experimental evidence that, in the proenzyme form of C1, the C1s serine protease domain is partly positioned inside the C1q cone and yields precise information about its orientation in the complex. These results provide further structural insights into the architecture of the C1 complex, allowing significant improvement of our current C1 model. PMID:20592021

  4. Project W-320, 241-C-106 sluicing: Construction specification W-320-C1

    SciTech Connect

    Bailey, J.W.

    1998-07-20

    Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits.

  5. Stereoselective synthesis of the C1-C29 part of amphidinol 3.

    PubMed

    Tsuruda, Takeshi; Ebine, Makoto; Umeda, Aya; Oishi, Tohru

    2015-01-16

    Stereoselective synthesis of the C1-C29 part of amphidinol 3 (AM3) was achieved. The C1-C20 part was assembled from three building blocks via regioselective cross metathesis to form the C4-C5 double bond and addition of an alkenyllithium and a lithium acetylide to two Weinreb amides followed by asymmetric reduction to form the C9-C10 and C14-C15 bonds, respectively. The C21-C29 part was synthesized via successive cross metathesis and oxa-Michael addition sequence to construct the 1,3-diol system at C25 and C27 and Brown asymmetric crotylation to introduce the stereogenic centers at C23 and C24. Coupling of the C1-C20 and C21-C29 parts was achieved by Julia-Kocienski olefination and regio- and stereoselective dihydroxylation of the C20-C21 double bond in the presence of the C4-C5 and C8-C9 double bonds to afford the C1-C29 part of AM3. PMID:25517178

  6. Emerging and Novel Functions of Complement Protein C1q

    PubMed Central

    Kouser, Lubna; Madhukaran, Shanmuga Priyaa; Shastri, Abhishek; Saraon, Anuvinder; Ferluga, Janez; Al-Mozaini, Maha; Kishore, Uday

    2015-01-01

    Complement protein C1q, the recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. It can bind various ligands derived from self, non-self, and altered self and modulate the functions of immune and non-immune cells including dendritic cells and microglia. C1q involvement in the clearance of apoptotic cells and subsequent B cell tolerance is more established now. Recent evidence appears to suggest that C1q plays an important role in pregnancy where its deficiency and dysregulation can have adverse effects, leading to preeclampsia, missed abortion, miscarriage or spontaneous loss, and various infections. C1q is also produced locally in the central nervous system, and has a protective role against pathogens and possible inflammatory functions while interacting with aggregated proteins leading to neurodegenerative diseases. C1q role in synaptic pruning, and thus CNS development, its anti-cancer effects as an immune surveillance molecule, and possibly in aging are currently areas of extensive research. PMID:26175731

  7. Spectroscopic study of the C 1Σ+ state of 7LiH

    NASA Astrophysics Data System (ADS)

    Chen, Jye-Jong; Luh, Wei-Tzou; Jeung, Gwang-Hi

    1999-03-01

    Forty-two vibrational (v=2-43) levels of the 7LiH C 1Σ+ excited electronic state have been observed by a pulsed optical-optical double resonance fluorescence depletion spectroscopic technique. The absolute vibrational numbering of the C 1Σ+ state is identified with the measurements of the isotopic shifts between 7LiH and 6LiH among several rotation-vibration bands of the C 1Σ+-A 1Σ+ electronic system, and it is further demonstrated by the consistency between observed spectral intensities and calculated ones. The highest observed quasi bound rotational level for the v=43 level is J=8. The spectral term values for those vibrational levels lying above v=33 occur in an irregular order. The level of v=34 lies mainly in the inner, tiny well. The term values for the observed rovibrational levels (2⩽v⩽32, 0⩽J⩽11) in the outer ionic well are described by a set of Dunham-type coefficients, with which a Rydberg-Klein-Rees (RKR) potential energy curve is constructed. This RKR potential is combined with an ab initio potential to construct an effective hybrid potential. The calculated electronic transition moment function for the C-A transition is also given.

  8. C1 Esterase Inhibitor Reduces Lower Extremity Ischemia/Reperfusion Injury and Associated Lung Damage

    PubMed Central

    Duehrkop, Claudia; Banz, Yara; Spirig, Rolf; Miescher, Sylvia; Nolte, Marc W.; Spycher, Martin; Smith, Richard A. G.; Sacks, Steven H.; Rieben, Robert

    2013-01-01

    Background Ischemia/reperfusion injury of lower extremities and associated lung damage may result from thrombotic occlusion, embolism, trauma, or surgical intervention with prolonged ischemia and subsequent restoration of blood flow. This clinical entity is characterized by high morbidity and mortality. Deprivation of blood supply leads to molecular and structural changes in the affected tissue. Upon reperfusion inflammatory cascades are activated causing tissue injury. We therefore tested preoperative treatment for prevention of reperfusion injury by using C1 esterase inhibitor (C1 INH). Methods and Findings Wistar rats systemically pretreated with C1 INH (n = 6), APT070 (a membrane-targeted myristoylated peptidyl construct derived from human complement receptor 1, n = 4), vehicle (n = 7), or NaCl (n = 8) were subjected to 3h hind limb ischemia and 24h reperfusion. The femoral artery was clamped and a tourniquet placed under maintenance of a venous return. C1 INH treated rats showed significantly less edema in muscle (P<0.001) and lung and improved muscle viability (P<0.001) compared to controls and APT070. C1 INH prevented up-regulation of bradykinin receptor b1 (P<0.05) and VE-cadherin (P<0.01), reduced apoptosis (P<0.001) and fibrin deposition (P<0.01) and decreased plasma levels of pro-inflammatory cytokines, whereas deposition of complement components was not significantly reduced in the reperfused muscle. Conclusions C1 INH reduced edema formation locally in reperfused muscle as well as in lung, and improved muscle viability. C1 INH did not primarily act via inhibition of the complement system, but via the kinin and coagulation cascade. APT070 did not show beneficial effects in this model, despite potent inhibition of complement activation. Taken together, C1 INH might be a promising therapy to reduce peripheral ischemia/reperfusion injury and distant lung damage in complex and prolonged surgical interventions requiring tourniquet application

  9. Workshops and incentive loans program for construction of solar greenhouses, grain dryers, window boxes and food dryers. Final performance report

    SciTech Connect

    Walker, D.H.

    1982-02-01

    A Solar Loan Fund was established to provide low-interest incentive loans to families desiring to construct their own solar devices, the only stipulations being allowance of reasonable public visitation and monitoring and employment of parish-trained construction teams if labor is to be hired. About 30 vocational agriculture students built window box collector units as part of their classroom experience, trying several designs. Later, 12 to 15 families built window box collectors for their use. A week long Energy Responsibility: Today and Tomorrow workshop was held involving construction projects and mini-seminars. Another workshop was held to construct bread box type solar hot water heaters, and yet another to build solar food dryers. (LEW)

  10. Biomechanical characteristics of C1-2 cable fixations.

    PubMed

    Dickman, C A; Crawford, N R; Paramore, C G

    1996-08-01

    The biomechanical characteristics of four different methods of C1-2 cable fixation were studied to assess the effectiveness of each technique in restoring atlantoaxial stability. Biomechanical testing was performed on the upper cervical spines of four human cadaveric specimens. Physiological range loading was applied to the atlantoaxial specimens and three-dimensional motion was analyzed with stereophotogrammetry. The load-deformation relationships and kinematics were measured, including the stiffness, the angular ranges of motion, the linear ranges of motion, and the axes of rotation. Specimens were nondestructively tested in the intact state, after surgical destabilization, and after each of four different methods of cable fixation. Cable fixation techniques included the interspinous technique, the Brooks technique, and two variants of the Gallie technique. All specimens were tested immediately after fixation and again after the specimen was fatigued with 6000 cycles of physiological range torsional loading. All four cable fixation methods were moderately flexible immediately; the different cable fixations allowed between 5 degrees and 40 degrees of rotational motion and between 0.6 and 7 mm of translational motion to occur at C1-2. The Brooks and interspinous methods controlled C1-2 motion significantly better than both of the Gallie techniques. The motion allowed by one of the Gallie techniques did not differ significantly from the motion of the unfixed destabilized specimens. All cable fixation techniques loosened after cyclic loading and demonstrated significant increases in C1-2 rotational and translational motions. The bone grafts shifted during cyclic loading, which reduced the effectiveness of the fixation. The locations of the axes of rotation, which were unconstrained and mobile in the destabilized specimens, became altered with cable fixation. The C1-2 cables constrained motion by shifting the axes of rotation so that C-1 rotated around the fixed cable

  11. 75 FR 57846 - Airworthiness Directives; Robert E. Rust, Jr. Model DeHavilland DH.C1 Chipmunk 21, DH.C1 Chipmunk...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ....gov . SUPPLEMENTARY INFORMATION: Airworthiness Directive 2010-18-12, amendment 39-16426 (75 FR 53861.... Model DeHavilland DH.C1 Chipmunk 21, DH.C1 Chipmunk 22, and DH.C1 Chipmunk 22A Airplanes AGENCY: Federal...Havilland DH.C1 Chipmunk 21, DH.C1 Chipmunk 22, and DH.C1 Chipmunk 22A airplanes. As published, the...

  12. 26 CFR 1.662(c)-1 - Different taxable years.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Different taxable years. 1.662(c)-1 Section 1...)-1 Different taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year of an estate or trust, the amount he is required to include in...

  13. 26 CFR 1.652(c)-1 - Different taxable years.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Different taxable years. 1.652(c)-1 Section 1... taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year of the trust, the amount he is required to include in gross income in accordance with...

  14. C1q Nephropathy: The Unique Underrecognized Pathological Entity.

    PubMed

    Devasahayam, Joe; Erode-Singaravelu, Gowrishankar; Bhat, Zeenat; Oliver, Tony; Chandran, Arul; Zeng, Xu; Dakshinesh, Paramesh; Pillai, Unni

    2015-01-01

    C1q nephropathy is a rare glomerular disease with characteristic mesangial C1q deposition noted on immunofluorescence microscopy. It is histologically defined and poorly understood. Light microscopic features are heterogeneous and comprise minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and proliferative glomerulonephritis. Clinical presentation is also diverse, and ranges from asymptomatic hematuria or proteinuria to frank nephritic or nephrotic syndrome in both children and adults. Hypertension and renal insufficiency at the time of diagnosis are common findings. Optimal treatment is not clear and is usually guided by the underlying light microscopic lesion. Corticosteroids are the mainstay of treatment, with immunosuppressive agents reserved for steroid resistant cases. The presence of nephrotic syndrome and FSGS appear to predict adverse outcomes as opposed to favorable outcomes in those with MCD. Further research is needed to establish C1q nephropathy as a universally recognized distinct clinical entity. In this paper, we discuss the current understanding of pathogenesis, histopathology, clinical features, therapeutic options, and outcomes of C1q nephropathy. PMID:26640759

  15. 26 CFR 1.514(c)-1 - Acquisition indebtedness.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) INCOME TAXES (CONTINUED) Taxation of Business Income of Certain Exempt Organizations § 1.514(c)-1... where State law provides that a tax lien attaches to property prior to the time when such lien becomes... and payable and the organization has had an opportunity to pay such lien in accordance with State...

  16. 26 CFR 53.4941(c)-1 - Special rules.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of private foundation X, lend one of the foundation's paintings to G, a disqualified person, for... EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(c)-1 Special...) (relating to tax on foundation managers). An initial tax is imposed on both A and B with respect to the...

  17. 26 CFR 53.4941(c)-1 - Special rules.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... of private foundation X, lend one of the foundation's paintings to G, a disqualified person, for... EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(c)-1 Special...) (relating to tax on foundation managers). An initial tax is imposed on both A and B with respect to the...

  18. 26 CFR 53.4941(c)-1 - Special rules.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of private foundation X, lend one of the foundation's paintings to G, a disqualified person, for... EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(c)-1 Special...) (relating to tax on foundation managers). An initial tax is imposed on both A and B with respect to the...

  19. 26 CFR 53.4941(c)-1 - Special rules.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... of private foundation X, lend one of the foundation's paintings to G, a disqualified person, for... EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(c)-1 Special...) (relating to tax on foundation managers). An initial tax is imposed on both A and B with respect to the...

  20. 26 CFR 53.4941(c)-1 - Special rules.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... of private foundation X, lend one of the foundation's paintings to G, a disqualified person, for... EXCISE TAXES (CONTINUED) FOUNDATION AND SIMILAR EXCISE TAXES Taxes on Self-Dealing § 53.4941(c)-1 Special...) (relating to tax on foundation managers). An initial tax is imposed on both A and B with respect to the...

  1. Pediatric hereditary angioedema due to C1-inhibitor deficiency

    PubMed Central

    2010-01-01

    Hereditary angioedema (HAE) resulting from the deficiency of the C1 inhibitor (C1-INH) is a rare, life-threatening disorder. It is characterized by attacks of angioedema involving the skin and/or the mucosa of the upper airways, as well as the intestinal mucosa. In approximately 50 per cent of cases, clinical manifestations may appear during childhood. The complex management of HAE in pediatric patients is in many respects different from the management of adults. Establishing the diagnosis early, preferably before the onset of clinical symptoms, is essential in cases with a positive family history. Complement studies usually afford accurate diagnosis, whereas molecular genetics tests may prove helpful in uncertain cases. Appropriate therapy, supported by counselling, suitable modification of lifestyle, and avoidance of triggering factors (which primarily include mechanical trauma, mental stress and airway infections in children) may spare the patient unnecessary surgery and may prevent mortality. Prompt control of edematous attacks, short-term prophylaxis and intermittent therapy are recommended as the primary means for the management of pediatric cases. Medicinal products currently used for the treatment of children with hereditary angioedema include antifibrinolytics, attenuated androgens, and C1-INH replacement therapy. Current guidelines favour antifibrinolytics for long-term prophylaxis because of their favorable safety profile but efficacy may be lacking. Attenuated androgens administered in the lowest effective dose are another option. C1-INH replacement therapy is also an effective and safe agent for children. Regular monitoring and follow-up of patients are necessary. PMID:20667121

  2. 26 CFR 1.652(c)-1 - Different taxable years.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Different taxable years. 1.652(c)-1 Section 1... taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year of the trust, the amount he is required to include in gross income in accordance with...

  3. 26 CFR 1.652(c)-1 - Different taxable years.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Different taxable years. 1.652(c)-1 Section 1... taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year of the trust, the amount he is required to include in gross income in accordance with...

  4. Review of Programs: Architecture; Architectural Technology; Landscape Architecture; Interior Design; Construction and Construction Technology; Building Construction; Urban and Regional Planning. Report to the Board of Regents, State University System of Florida.

    ERIC Educational Resources Information Center

    McMinn, William G.

    This report is an update of a report on the development and status of various programs in architecture and related fields in the State University System of Florida, a report that was submitted to the Board of Regents in May 1983. The objectives of this updated report, like those of the earlier one, are to review the anticipated needs of the…

  5. The Social Construction of "Evidence-Based" Drug Prevention Programs: A Reanalysis of Data from the Drug Abuse Resistance Education (DARE) Program

    ERIC Educational Resources Information Center

    Gorman, Dennis M.; Huber, J. Charles, Jr.

    2009-01-01

    This study explores the possibility that any drug prevention program might be considered "evidence-based" given the use of data analysis procedures that optimize the chance of producing statistically significant results by reanalyzing data from a Drug Abuse Resistance Education (DARE) program evaluation. The analysis produced a number of…

  6. "You Get to Be Yourself": Visual Arts Programs, Identity Construction and Learners of English as an Additional Language

    ERIC Educational Resources Information Center

    Wielgosz, Meg; Molyneux, Paul

    2015-01-01

    Students learning English as an additional language (EAL) in Australian schools frequently struggle with the cultural and linguistic demands of the classroom while concurrently grappling with issues of identity and belonging. This article reports on an investigation of the role primary school visual arts programs, distinct programs with a…

  7. Harlan County Public Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Warren, Carol E.

    The Harlan County Public Library Literacy Project (Kentucky) provided rural-oriented, basic literacy, and oral history programs to a community of 100,000-200,000. The goal of the project was to produce six booklets about local people and issues, to be used as literacy materials in programs with Appalachian students. Students wanted to produce…

  8. Lonesome Pine Regional Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Deel, Rosemary

    This final performance report provides project outcome information and data to the U.S. Department of Education for the federally-funded Library Literacy Program. The Lonesome Pine Regional Library (Wise, Virginia) conducted a project that involved recruitment, retention, public awareness, training, rural oriented programs, basic literacy, and…

  9. Santa Clara County Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Willingham, Taylor; Trajico, Charity A.; Levy, Michael

    This final performance report provides project outcome information and data to the U.S. Department of Education for the federally-funded Library Literacy Program. The Santa Clara County (California) Library Reading Program Computer Aided Literacy (CAL) Project involved recruitment, public awareness, training, basic literacy, collection…

  10. Alameda County Library Workplace Literacy, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Drobner, Sherry

    The Adult Literacy Program at the Alameda County Library provided employment oriented programs. The project served a community of over 200,000 people, and targeted workforce/workplace learners. The project served 578 adult learners and provided 35,904 hours of direct tutoring service. The report provides a comparison of actual accomplishments to…

  11. Creating an Anti-Bullying Culture in Secondary Schools: Characteristics to Consider When Constructing Appropriate Anti-Bullying Programs

    ERIC Educational Resources Information Center

    Jones, Joseph R.; Augustine, Sharon Murphy

    2015-01-01

    Bullying in schools is a tremendous challenge that many secondary educators are attempting to address within their school environments. However, educators are often unsure of the attributes of an effective anti-bullying program; thus, they tend to create programs on a "trial and error" basis. This article provides an overview of the…

  12. A job safety program for construction workers designed to reduce the potential for occupational injury using tool box training sessions and computer-assisted biofeedback stress management techniques.

    PubMed

    Johnson, Kenneth A; Ruppe, Joan

    2002-01-01

    This project was conducted with a multicultural construction company in Hawaii, USA. The job duties performed included drywall and carpentry work. The following objectives were selected for this project: (a) fire prevention training and inspection of first aid equipment; (b) blood-borne pathogen training and risk evaluation; (c) ergonomic and risk evaluation intervention program; (d) electrical safety training and inspection program; (e) slips, trips, and falls safety training; (f) stress assessment and Personal Profile System; (g) safety and health program survey; (h) improving employee relations and morale by emphasizing spirituality; and (i) computer-assisted biofeedback stress management training. Results of the project indicated that observed safety hazards, reported injuries, and levels of perceived stress. were reduced for the majority of the population. PMID:12189103

  13. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.249 What is the Secretary's role in a... AFA; (c) The Secretary may conduct on-site monitoring visits as negotiated in the AFA; (d)...

  14. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.249 What is the Secretary's role in a... AFA; (c) The Secretary may conduct on-site monitoring visits as negotiated in the AFA; (d)...

  15. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.249 What is the Secretary's role in a... AFA; (c) The Secretary may conduct on-site monitoring visits as negotiated in the AFA; (d)...

  16. Isolation and mode of action of bacteriocin BacC1 produced by nonpathogenic Enterococcus faecium C1.

    PubMed

    Goh, H F; Philip, K

    2015-08-01

    Lactic acid bacteria are present in fermented food products and help to improve shelf life and enhance the flavor of the food. They also produce metabolites such as bacteriocins to prevent the growth of undesirable or pathogenic bacteria. In this study, Enterococcus faecium C1 isolated from fermented cow milk was able to produce bacteriocin BacC1 and inhibit the growth of selected food-spoilage bacteria. The bacteriocin was purified through 4 steps: ammonium sulfate precipitation, hydrophobic interaction column, a series of centrifugal steps, and finally reversed-phase HPLC. A membrane permeability test using SYTOX green dye (Invitrogen, Grand Island, NY) showed that the bacteriocin caused significant disruptions to the test bacterial membrane, as shown by transmission electron microscopy. The molecular weight of the BacC1 obtained from SDS-PAGE was around 10kDa, and N-terminal sequencing revealed a partial amino acid sequence of BacC1: GPXGPXGP. The bacterial strain was nonhemolytic and not antibiotic resistant. Therefore, it has high potential for application in the food industry as an antimicrobial agent to extend the shelf life of food products. PMID:26004828

  17. A review of the constructs, curriculum and training data from a workforce development program for recovery support specialists.

    PubMed

    Stoneking, Beth C; McGuffin, Beverly A

    2007-01-01

    The theoretical underpinnings, training content and initial training data of a workforce development program are described. The program was designed for people with psychiatric and/or substance use disorders, and provides skills to improve their employability in the behavioral health system. Trainees rated their knowledge, skills and attitudes as improved after training. Supervisor ratings of participants after three months of employment are consistent with the participant's self-ratings. PMID:18018953

  18. Dr. Wernher von Braun Presents Saturn C-1 Progress for the Senate Committee of Aeronautical and

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Progress in the Saturn program, depicted below, was described by Dr. Wernher von Braun, Marshall Space Flight Center (MSFC) Director, in an appearance before the Senate Committee of Aeronautical and Space Sciences. 'The flight configuration of the giant three-stage Saturn C-1 rocket (later called Saturn I Block I) is seen in the Fabrication and Assembly Engineering Division at MSFC. Dwarfed by the 180-foot C-1 are a Juno II rocket (left rear) and a Mercury-Redstone rocket (front foreground). The C-1 (first version of the Saturn rocket) is composed of an S-1 first stage or booster (rear), powered by eight H-1 engines having a thrust of 1,500,000 pounds, followed by a dummy S-IV second stage and a dummy S-V third stage. The 'live' S-IV for later flights, under development by Douglas Aircraft Co., will be powered by four Pratt Whitney LR-119 engines having 17,500,000 pounds thrust each. The live S-V, under development by Convair Division of General Dynamics Corp., will use two LR-119 engines. With all three stages live, the C-1 will be capable of placing 19,000 pounds into a 300-mile Earth orbit, sending 5,000 pounds to escape velocity, or lofting 2,500 pounds to Mars or Venus. The second version Saturn C-2 (later called Saturn 1 Block II) would double these capabilities. Early C-1 flights will employ a live S-1 with dummy upper stages. The first such flight is scheduled late this year.'

  19. The C1s core line in irradiated graphite

    SciTech Connect

    Speranza, Giorgio; Minati, Luca; Anderle, Mariano

    2007-08-15

    Recently, plasma deposited amorphous carbon films have been the subject of extensive experimental and theoretical investigations aimed at correlating their electronic, structural, and mechanical properties to growth parameters. To investigate these properties, different spectral parameters reflecting the electronic structure of carbon-based materials are proposed in literature. The effects of various electronic configurations on the carbon photoelectron spectra are analyzed here with particular attention to C1s core line with the aim to better interpret its structure. The latter is commonly fitted under the assumption that it can be described by using just two spectral components related to sp{sup 2} and sp{sup 3} hybrids. Their relative intensities are then used to estimate the sp{sup 2} and sp{sup 3} phases. We show that, in the presence of an amorphous network, the C1s line shape is the result of a more complex mixture of electronic states. Ar{sup +} irradiated graphite and successive oxidation was used to identify spectral features to better describe the C1s line shape.

  20. C1 CHEMISTRY FOR THE PRODUCTION OF ULTRA-CLEAN LIQUID TRANSPORTATION FUELS AND HYDROGEN

    SciTech Connect

    Gerald P. Huffman

    2003-03-31

    Faculty and students from five universities--the University of Kentucky, University of Pittsburgh, University of Utah, West Virginia University, and Auburn University--are collaborating in a research program to develop C1 chemistry processes to produce ultra-clean liquid transportation fuels and hydrogen, the zero-emissions transportation fuel of the future. The feedstocks contain one carbon atom per molecular unit. They include synthesis gas (syngas), a mixture of carbon monoxide and hydrogen produced by coal gasification or reforming of natural gas, methane, methanol, carbon dioxide, and carbon monoxide. An important objective is to develop C1 technology for the production of transportation fuel from domestically plentiful resources such as coal, coalbed methane, and natural gas. An Industrial Advisory Board with representatives from Chevron-Texaco, Eastman Chemical, Conoco-Phillips, Energy International, the Department of Defense, and Tier Associates provides guidance on the practicality of the research.

  1. Improvement in the occupational health program in a Finnish construction company by means of systematic workplace investigation of job load and hazard analysis.

    PubMed

    Mattila, M

    1989-01-01

    The aim of the present study was to improve an occupational health program by means of systematic workplace investigations. The 8-month study was done at three building sites of one construction firm. The method for workplace investigations was a simple job hazard analysis of chemical hazards, physical hazards, physical work load, mental stress, and risk of injury, each factor being rated on a three-point scale. Information was gathered by observations, interviews, and a worker questionnaire. Occupational health and safety personnel and worker representatives dealt with problems cooperatively. Together they assessed occupational loads and hazards, whereafter the occupational health and safety personnel devised an occupational health care program and proposed preventive measures. The workplace investigation method proved to function well. It improved the occupational health care program, produced an overall analysis of occupational hazards, and dramatically increased the number and quality of proposed preventive measures. The new method was evaluated to be clearly superior to previous practices and was implemented at moderate cost. The study showed that attention to issues of environmental and occupational health can effectively prevent health impairment even in difficult setting such as construction work. More research is needed for effective utilization of information accumulated by systematic workplace investigations. PMID:2929609

  2. Building Technology: Under Construction.

    ERIC Educational Resources Information Center

    Weltman, June

    2002-01-01

    Discusses a number of community college-based training concepts for the construction trades. These programs integrate classroom, lab, and work experience, and some offer credits toward applied sciences or other degrees. Describes the Florida Construction Institute at Florida Community College, Jacksonville, and other construction education…

  3. Simplifying the construction of domain-specific automatic programming systems: The NASA automated software development workstation project

    NASA Technical Reports Server (NTRS)

    Allen, Bradley P.; Holtzman, Peter L.

    1987-01-01

    An overview is presented of the Automated Software Development Workstation Project, an effort to explore knowledge-based approaches to increasing software productivity. The project focuses on applying the concept of domain specific automatic programming systems (D-SAPSs) to application domains at NASA's Johnson Space Center. A version of a D-SAPS developed in Phase 1 of the project for the domain of space station momentum management is described. How problems encountered during its implementation led researchers to concentrate on simplifying the process of building and extending such systems is discussed. Researchers propose to do this by attacking three observed bottlenecks in the D-SAPS development process through the increased automation of the acquisition of programming knowledge and the use of an object oriented development methodology at all stages of the program design. How these ideas are being implemented in the Bauhaus, a prototype workstation for D-SAPS development is discussed.

  4. Simplifying the construction of domain-specific automatic programming systems: The NASA automated software development workstation project

    NASA Technical Reports Server (NTRS)

    Allen, Bradley P.; Holtzman, Peter L.

    1988-01-01

    An overview is presented of the Automated Software Development Workstation Project, an effort to explore knowledge-based approaches to increasing software productivity. The project focuses on applying the concept of domain specific automatic programming systems (D-SAPSs) to application domains at NASA's Johnson Space Flight Center. A version of a D-SAPS developed in Phase 1 of the project for the domain of space station momentum management is described. How problems encountered during its implementation led researchers to concentrate on simplifying the process of building and extending such systems is discussed. Researchers propose to do this by attacking three observed bottlenecks in the D-SAPS development process through the increased automation of the acquisition of programming knowledge and the use of an object oriented development methodology at all stages of the program design. How these ideas are being implemented in the Bauhaus, a prototype workstation for D-SAPS development is discussed.

  5. Lebanon Community Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Kline, Patricia A.; Long, Sandy

    The Lebanon County Family Literacy Program, a project of the Lebanon Community Library (Pennsylvania), targeted intergenerational/families and focused on coalition building, public awareness, training, and collection development. The Lebanon Community Library serves as: a centralized location for storing and disseminating materials and handouts on…

  6. Measuring the Effectiveness of Transfer of Learning Constructs and Intent to Transfer in a Simulation-Based Leadership Training Program

    ERIC Educational Resources Information Center

    Hix, Joanne W.

    2013-01-01

    The purpose of business training programs is to improve performance, which improved performance changes leadership behaviors based on the knowledge, skills, and abilities (KSAs) learned in training. One of the most common criticisms of leadership training is the tendency to focus on teaching theory but not on applying theory into practice, that…

  7. Pottsville Free Public Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Smink, Nancy J.; Bridal, Wendy

    This final performance report provides project outcome information and data to the U.S. Department of Education for the federally-funded Library Literacy Program. The Pottsville Free Public Library conducted a project that involved recruitment, retention, public awareness, training, basic literacy, collection development, tutoring, other…

  8. West Georgia Regional Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Willis, Roni L.

    This final performance report provides project outcome information and data to the U.S. Department of Education for the federally-funded Library Literacy Program. The West Georgia Regional Library conducted a project from October 1992 until September 1993 that involved collection development and providing tutoring services to adult learners in a…

  9. Onondaga County Public Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Nottingham, Sharon

    A literacy project was a cooperative effort of the Onondaga County (New York) Public Library, Literacy Volunteers of Greater Syracuse, and Aurora (a private non-profit agency for the deaf) to establish a program to teach deaf adults to read. This report, which describes the project, begins with a section that provides quantitative data. The next…

  10. Teacher Candidates Learning from English Learners: Constructing Concepts of Language and Culture in Tuesday's Tutors After-School Program

    ERIC Educational Resources Information Center

    Fitts, Shanan; Gross, Lisa A.

    2012-01-01

    In teacher preparation programs across the United States, early field experiences are considered to be an effective method of providing teacher candidates with opportunities to observe and interact with children (National Council for Accreditation for Teacher Education (NCATE, 2010). These practicum arrangements assist candidates in developing…

  11. Translating Evidence Based Violence and Drug Use Prevention to Obesity Prevention: Development and Construction of the Pathways Program

    ERIC Educational Resources Information Center

    Sakuma, Kari-Lyn K.; Riggs, Nathaniel R.; Pentz, Mary Ann

    2012-01-01

    Effective school-based obesity prevention programs are needed to prevent and reduce the growing obesity risk among youth. Utilizing the evidence-rich areas of violence and substance use prevention, translation science may provide an efficient means for developing curricula across multiple health behaviors. This paper introduces Pathways to Health,…

  12. Pikes Peak Library District, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Hammond, Susan; Maio, Jean

    This final performance report for the Pikes Peak Library District literacy project begins with a section that provides quantitative data. The next section compares actual accomplishments to the project goal and related objectives for 1993: to reduce obstacles to success of students enrolled in the Right To Read program through student…

  13. Multigroup Construct Validity Evidence of the "HOPE Scale": Instrumentation to Identify Low-Income Elementary Students for Gifted Programs

    ERIC Educational Resources Information Center

    Peters, Scott J.; Gentry, Marcia

    2010-01-01

    Students with exceptional academic potential who come from low-income families are frequently not identified for and consequently are underrepresented in gifted and talented programs. Because of this, new means of identifying such children must be developed. This article presents the findings of exploratory and confirmatory factor analyses…

  14. Constructing Knowledge with an Agent-Based Instructional Program: A Comparison of Cooperative and Individual Meaning Making

    ERIC Educational Resources Information Center

    Moreno, Roxana

    2009-01-01

    Participants in the present study were 87 college students who learned about botany using an agent-based instructional program with three different learning approaches: individual, jigsaw, or cooperative learning. Results showed no differences among learning approaches on retention. Students in jigsaw groups reported higher cognitive load during…

  15. Eagle Valley Library District, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Gray, Colleen

    This final performance report for the Eagle Valley Library District literacy project begins with a section that provides quantitative data. The next section compares actual accomplishments to the following objectives for 1992-93: (1) design and implement a literacy program that provides instruction to adults who wish to develop or improve reading,…

  16. Linearization of class C1 for contractions on Banach spaces

    NASA Astrophysics Data System (ADS)

    Rodrigues, Hildebrando M.; Solà-Morales, J.

    In this work we prove a C1-linearization result for contraction diffeomorphisms, near a fixed point, valid in infinite-dimensional Banach spaces. As an intermediate step, we prove a specific result of existence of invariant manifolds, which can be interesting by itself and that was needed on the proof of our main theorem. Our results essentially generalize some classical results by P. Hartman in finite dimensions, and a result of Mora-Sola-Morales in the infinite-dimensional case. It is shown that the result can be applied to some abstract systems of semilinear damped wave equations.

  17. Reduction of CO2 to C1 products and fuel

    USGS Publications Warehouse

    Mill, T.; Ross, D.

    2002-01-01

    Photochemical semiconductor processes readily reduced CO2 to a broad range of C1 products. However the intrinsic and solar efficiencies for the processes were low. Improved quantum efficiencies could be realized utilizing quantum-sized particles, but at the expense of using less of the visible solar spectrum. Conversely, semiconductors with small bandgaps used more of the visible solar spectrum at the expense of quantum efficiency. Thermal reduction of CO2 with Fe(II) was thermodynamically favored for forming many kinds of organic compounds and occurred readily with olivine and other Fe(II) minerals above 200??C to form higher alkanes and alkenes. No added hydrogen was required.

  18. C1-Cx revisited: intramolecular synergism in a cellulase.

    PubMed Central

    Din, N; Damude, H G; Gilkes, N R; Miller, R C; Warren, R A; Kilburn, D G

    1994-01-01

    Endoglucanase A (CenA) from the bacterium Cellulomonas fimi is composed of a catalytic domain and a nonhydrolytic cellulose-binding domain that can function independently. The individual domains interact synergistically in the disruption and hydrolysis of cellulose fibers. This intramolecular synergism is distinct from the well-known intermolecular synergism between individual cellulases. The catalytic domain corresponds to the hydrolytic Cx system and the cellulose-binding domain corresponds to the nonhydrolytic C1 system postulated by Reese et al. [Reese, E. T., Sui, R. G. H. & Levinson, H. S. (1950) J. Bacteriol. 59, 485-497] to be required for the hydrolysis of cellulose. PMID:7972069

  19. Determining the locations of the various CIRC recording format information blocks (user data blocks, C2 and C1 words and EFM frames) on a recorded compact disc

    NASA Technical Reports Server (NTRS)

    Howe, Dennis G.

    1993-01-01

    Just prior to its being EFM modulated (i.e., converted to eight-to-fourteen channel data by the EFM encoder) and written to a Compact Disc (CD), information that passes through the CIRC Block Encoder is grouped into 33-byte blocks referred to as EFM frames. Twenty four of the bytes that make up a given EFM frame are user data that was input into the CIRC encoder at various (different) times, 4 of the bytes of this same EFM frame were created by the C2 ECC encoder (each at a different time), and another 4 were created by the C1 ECC encoder (again, each at a different time). The one remaining byte of the given EFM frame, which is known as the EFM frame C&D (for Control & Display) byte, carries information that identifies which portion of the current disc program track the given EFM frame belongs to and also specifies the location of the given EFM frame on the disc (in terms of a time stamp that has a resolution of l/75th second, or 98 EFM frames). (Note: since the program track and time information is stored as a 98-byte word, a logical group consisting of 98 consecutive EFM frames must be read, and their respective C&D bytes must be catenated and decoded, before the program track identification and time position information that pertains to the entire block of 98 EFM frames can be obtained.) The C&D byte is put at the start (0th byte) of an EFM frame in real time; its placement completes the construction of the EFM frame - it is assigned just before the EFM frame enters the EFM encoder. Four distinct blocks of data are referred to: 24-byte User Input Data Blocks; 28-byte C2 words; 32-byte C1 words; and 33-byte EFM frames.

  20. C1 inhibitor deficiency: 2014 United Kingdom consensus document

    PubMed Central

    Longhurst, H J; Tarzi, M D; Ashworth, F; Bethune, C; Cale, C; Dempster, J; Gompels, M; Jolles, S; Seneviratne, S; Symons, C; Price, A; Edgar, D

    2015-01-01

    C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient patients, representing a joint venture between the United Kingdom Primary Immunodeficiency Network and Hereditary Angioedema UK. To develop the consensus, we assembled a multi-disciplinary steering group of clinicians, nurses and a patient representative. This steering group first met in 2012, developing a total of 48 recommendations across 11 themes. The statements were distributed to relevant clinicians and a representative group of patients to be scored for agreement on a Likert scale. All 48 statements achieved a high degree of consensus, indicating strong alignment of opinion. The recommendations have evolved significantly since the 2005 document, with particularly notable developments including an improved evidence base to guide dosing and indications for acute treatment, greater emphasis on home therapy for acute attacks and a strong focus on service organization. PMID:25605519

  1. C1 inhibitor deficiency: 2014 United Kingdom consensus document.

    PubMed

    Longhurst, H J; Tarzi, M D; Ashworth, F; Bethune, C; Cale, C; Dempster, J; Gompels, M; Jolles, S; Seneviratne, S; Symons, C; Price, A; Edgar, D

    2015-06-01

    C1 inhibitor deficiency is a rare disorder manifesting with recurrent attacks of disabling and potentially life-threatening angioedema. Here we present an updated 2014 United Kingdom consensus document for the management of C1 inhibitor-deficient patients, representing a joint venture between the United Kingdom Primary Immunodeficiency Network and Hereditary Angioedema UK. To develop the consensus, we assembled a multi-disciplinary steering group of clinicians, nurses and a patient representative. This steering group first met in 2012, developing a total of 48 recommendations across 11 themes. The statements were distributed to relevant clinicians and a representative group of patients to be scored for agreement on a Likert scale. All 48 statements achieved a high degree of consensus, indicating strong alignment of opinion. The recommendations have evolved significantly since the 2005 document, with particularly notable developments including an improved evidence base to guide dosing and indications for acute treatment, greater emphasis on home therapy for acute attacks and a strong focus on service organization. PMID:25605519

  2. Land validation for GCOM-C1/SGLI using UAV

    NASA Astrophysics Data System (ADS)

    Honda, Yhosiaki; Kajiwara, Koji; Sharma, Ram; Ono, Akiko; Imaoka, Keiji; Murakami, Hiroshi; Hori, Masahiro; Ono, Yusaku; Rostand, Dim

    2012-09-01

    Japan Aerospace Exploration Agency (JAXA) is going to launch new Earth observation satellite GCOM-C1 in near future. The core sensor of GCOM-C1, Second Generation Global Imager (SGLI) has a set of along track slant viewing Visible and Near Infrared Radiometer (VNR). These multi-angular views aim to detect the structural information from vegetation canopy, especially forest canopy, for estimating productivity of the vegetation. SGLI Land science team has been developing the algorithm for above ground biomass, canopy roughness index, shadow index, etc. In this paper, we introduce the ground observation method developed by using Unmanned Aerial Vehicle (UAV) in order to contribute the algorithm development and its validation. Mainly, multi-angular spectral observation method and simple BRF model have been developed for estimating slant view response of forest canopy. The BRF model developed by using multi-angular measurement has been able to obtain structural information from vegetation canopy. In addition, we have conducted some observation campaigns on typical forest in Japan in collaboration with other science team experienced with vegetation phenology and carbon flux measurement. Primary results of these observations are also be demonstrated.

  3. Prophylaxis in hereditary angioedema (HAE) with C1 inhibitor deficiency.

    PubMed

    Greve, Jens; Strassen, Ulrich; Gorczyza, Marina; Dominas, Nina; Frahm, Uta-Marie; Mühlberg, Heike; Wiednig, Michaela; Zampeli, Vasiliki; Magerl, Markus

    2016-03-01

    Hereditary angioedema (HAE) is a rare congenital disorder characterized by recurrent episodes of subcutaneous or submucosal edema. Laryngeal manifestations can be life-threatening. In the majority of cases, the disease can be adequately treated with an on-demand approach - in some cases, however, short- or long-term prophylaxis is indicated. Attenuated androgens used to be the drugs of choice, but they are associated with considerable side effects and no longer commercially available in the German-speaking countries of the EU. They are currently being replaced by more effective and more tolerable agents such C1-inhibitors, the kallikrein inhibitor ecallantide, and the B2 receptor antagonist icatibant, which have recently obtained market authorization. These new drugs have had a major impact, especially on the indications and procedures for long-term prophylaxis. According to the most recent international consensus papers and our own experience, self-administered C1-inhibitors are now the first option for long-term prophylactic therapy. The decision for prophylaxis should no longer be based on single parameters such as the frequency of attacks but on adequate overall disease control including quality of life. More drugs are currently being developed, which may lead to further changes in the treatment algorithms of HAE. PMID:26972189

  4. Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis

    PubMed Central

    2012-01-01

    Background In invertebrates, the medicinal leech is considered to be an interesting and appropriate model to study neuroimmune mechanisms. Indeed, this non-vertebrate animal can restore normal function of its central nervous system (CNS) after injury. Microglia accumulation at the damage site has been shown to be required for axon sprouting and for efficient regeneration. We characterized HmC1q as a novel chemotactic factor for leech microglial cell recruitment. In mammals, a C1q-binding protein (C1qBP alias gC1qR), which interacts with the globular head of C1q, has been reported to participate in C1q-mediated chemotaxis of blood immune cells. In this study, we evaluated the chemotactic activities of a recombinant form of HmC1q and its interaction with a newly characterized leech C1qBP that acts as its potential ligand. Methods Recombinant HmC1q (rHmC1q) was produced in the yeast Pichia pastoris. Chemotaxis assays were performed to investigate rHmC1q-dependent microglia migration. The involvement of a C1qBP-related molecule in this chemotaxis mechanism was assessed by flow cytometry and with affinity purification experiments. The cellular localization of C1qBP mRNA and protein in leech was investigated using immunohistochemistry and in situ hybridization techniques. Results rHmC1q-stimulated microglia migrate in a dose-dependent manner. This rHmC1q-induced chemotaxis was reduced when cells were preincubated with either anti-HmC1q or anti-human C1qBP antibodies. A C1qBP-related molecule was characterized in leech microglia. Conclusions A previous study showed that recruitment of microglia is observed after HmC1q release at the cut end of axons. Here, we demonstrate that rHmC1q-dependent chemotaxis might be driven via a HmC1q-binding protein located on the microglial cell surface. Taken together, these results highlight the importance of the interaction between C1q and C1qBP in microglial activation leading to nerve repair in the medicinal leech. PMID:22356764

  5. Programs.

    ERIC Educational Resources Information Center

    Community College Journal, 1996

    1996-01-01

    Includes a collection of eight short articles describing model community college programs. Discusses a literacy program, a mobile computer classroom, a support program for at-risk students, a timber-harvesting program, a multimedia presentation on successful women graduates, a career center, a collaboration with NASA, and an Israeli engineering…

  6. C1,1 regularity for degenerate elliptic obstacle problems

    NASA Astrophysics Data System (ADS)

    Daskalopoulos, Panagiota; Feehan, Paul M. N.

    2016-03-01

    The Heston stochastic volatility process is a degenerate diffusion process where the degeneracy in the diffusion coefficient is proportional to the square root of the distance to the boundary of the half-plane. The generator of this process with killing, called the elliptic Heston operator, is a second-order, degenerate-elliptic partial differential operator, where the degeneracy in the operator symbol is proportional to the distance to the boundary of the half-plane. In mathematical finance, solutions to the obstacle problem for the elliptic Heston operator correspond to value functions for perpetual American-style options on the underlying asset. With the aid of weighted Sobolev spaces and weighted Hölder spaces, we establish the optimal C 1 , 1 regularity (up to the boundary of the half-plane) for solutions to obstacle problems for the elliptic Heston operator when the obstacle functions are sufficiently smooth.

  7. [C1Q NEPHROPATHY: CASE REPORTS AND LITERATURE REVIEW].

    PubMed

    Galešić, Krešimir; Horvatić, Ivica; Batinić, Danica; Milošević, Danko; Saraga, Marijan; Durdov, Merica Glavina; Ljubanović, Danica Galešić

    2015-01-01

    C1q nephropathy is considered a form of glomerulonephritis, defined by histological findings of dominant Clq immune deposits in renal biopsy. It is a rare disease, most often manifested in children and young adults. The most common clinical manifestation of the disease is nephrotic syndrome, but other renal syndromes could also be found. The cause of the disease is not known, but the immune pathogenesis could be assumed. Often, resistance to glucocorticoid or other immunosuppressive therapy is present, potentially leading to chronic renal insufficiency. We present ten patients with renal biopsy and clinical findings of Clq nephropathy. None of the patients had clinical or serological manifestations of systemic lupus. All patients had normal findings of C3 and C4 components of complement, as well as normal ANF, anti-dsD-NA and ANCA antibodies. PMID:26749950

  8. A Selection of Recent Advances in C1 Chemistry.

    PubMed

    Mesters, Carl

    2016-06-01

    This review presents a selection of recent publications related to the chemistry and catalysis of C1 molecules, including methane, methanol, carbon monoxide, and carbon dioxide. These molecules play an important role in the current supply of energy and chemicals and will likely become even more relevant because of the need to decarbonize fuels (shift from coal to natural gas) in line with CO2 capture and use to mitigate global warming, as well as a gradual shift on the supply side from crude oil to natural gas. This review includes both recent industrial developments, such as the huge increase in methanol-to-olefins-capacity build in China and the demonstration of oxidative coupling of methane, and scientific developments in these chemistries facilitated by improved capabilities in, for example, analytical tools and computational modeling. PMID:27276549

  9. Plasma enhanced C1 chemistry for green technology

    NASA Astrophysics Data System (ADS)

    Nozaki, Tomohiro

    2013-09-01

    Plasma catalysis is one of the innovative next generation green technologies that meet the needs for energy and materials conservation as well as environmental protection. Non-thermal plasma uniquely generates reactive species independently of reaction temperature, and these species are used to initiate chemical reactions at unexpectedly lower temperatures than normal thermochemical reactions. Non-thermal plasma thus broadens the operation window of existing chemical conversion processes, and ultimately allows modification of the process parameters to minimize energy and material consumption. We have been specifically focusing on dielectric barrier discharge (DBD) as one of the viable non-thermal plasma sources for practical fuel reforming. In the presentation, room temperature one-step conversion of methane to methanol and hydrogen using a miniaturized DBD reactor (microplasma reactor) is highlighted. The practical impact of plasma technology on existing C1-chemistry is introduced, and then unique characteristics of plasma fuel reforming such as non-equilibrium product distribution is discussed.

  10. C(1) metabolism and CVD outcomes in older adults.

    PubMed

    McNulty, Helene; Strain, J J; Pentieva, Kristina; Ward, Mary

    2012-05-01

    CVD is the most common cause of death in people over 65 years. This review considers the latest evidence for a potential protective effect of C(1) donors (folate and the metabolically related B-vitamins) in CVD. Such an effect may or may not be mediated via the role of these nutrients in maintaining plasma homocysteine concentrations within a desirable range. Despite predictions from epidemiological studies that lowering plasma homocysteine would reduce cardiovascular risk, several secondary prevention trials in at-risk patients published since 2004 have failed to demonstrate a benefit of homocysteine-lowering therapy with B-vitamins on CVD events generally. All these trials were performed in CVD patients with advanced disease; thus current evidence suggests that intervention with high-dose folic acid is of no benefit in preventing another event, at least in the case of heart disease. The evidence at this time, however, is stronger for stroke, with meta-analyses of randomised trials showing that folic acid reduces the risk of stroke, particularly in people with no history of stroke. Genetic studies provide convincing evidence to support a causal relationship between sub-optimal B-vitamin status and CVD. People homozygous for the common C677T variant in the gene encoding the folate-metabolising enzyme, methylenetetrahydrofolate reductase (MTHFR), typically have a 14-21% higher risk of CVD. Apart from folate, riboflavin is required as a co-factor for MTHFR. New evidence shows that riboflavin intervention results in marked lowering of blood pressure, specifically in patients with the MTHFR 677TT genotype. This novel gene-nutrient interaction may provide insights as to the mechanism that links C(1) metabolism with CVD outcomes. PMID:22152927

  11. C1 Chemistry for the Production of Ultra-Clean Liquid Transportation Fuels and Hydrogen

    SciTech Connect

    Gerald P. Huffman

    2003-03-31

    Faculty and students from five universities--the University of Kentucky, University of Pittsburgh, University of Utah, West Virginia University, and Auburn University--are collaborating in a research program to develop C1 chemistry processes to produce ultra-clean liquid transportation fuels and hydrogen, the zero-emissions transportation fuel of the future. The feedstocks contain one carbon atom per molecular unit. They include synthesis gas (syngas), a mixture of carbon monoxide and hydrogen produced by coal gasification or reforming of natural gas, methane, methanol, carbon dioxide, and carbon monoxide. An important objective is to develop C1 technology for the production of transportation fuel from domestically plentiful resources such as coal, coalbed methane, and natural gas. An Industrial Advisory Board with representatives from Chevron-Texaco, Eastman Chemical, Conoco-Phillips, Energy International, the Department of Defense, and Tier Associates provides guidance on the practicality of the research. The current report presents results obtained in this research program during the first six months of the subject contract (DE-FC26-02NT-4159), from October 1, 2002 through March 31, 2003.

  12. C1 Chemistry for the Production of Ultra-Clean Liquid Transportation Fuels and Hydrogen

    SciTech Connect

    Gerald P. Huffman

    2005-03-31

    Faculty and students from five universities--the University of Kentucky, University of Pittsburgh, University of Utah, West Virginia University, and Auburn University--are collaborating in a research program to develop C1 chemistry processes to produce ultra-clean liquid transportation fuels and hydrogen, the zero-emissions transportation fuel of the future. The feedstocks contain one carbon atom per molecular unit. They include synthesis gas (syngas), a mixture of carbon monoxide and hydrogen produced by coal gasification or reforming of natural gas, methane, methanol, carbon dioxide, and carbon monoxide. An important objective is to develop C1 technology for the production of liquid transportation fuel and hydrogen from domestically plentiful resources such as coal, coalbed methane, and natural gas. An Industrial Advisory Board with representatives from Chevron-Texaco, Eastman Chemical, Conoco-Phillips, the Air Force Research Laboratory, the U.S. Army National Automotive Center (Tank & Automotive Command--TACOM), and Tier Associates provides guidance on the practicality of the research. The current report presents results obtained in this research program during the six months of the subject contract from October 1, 2002 through March 31, 2003. The results are presented in thirteen detailed reports on research projects headed by various faculty members at each of the five CFFS Universities. Additionally, an Executive Summary has been prepared that summarizes the principal results of all of these projects during the six-month reporting period.

  13. C1 CHEMISTRY FOR THE PRODUCTION OF ULTRA-CLEAN LIQUID TRANSPORTATION FUELS AND HYDROGEN

    SciTech Connect

    Gerald P. Huffman

    2004-03-31

    Faculty and students from five universities--the University of Kentucky, University of Pittsburgh, University of Utah, West Virginia University, and Auburn University--are collaborating in a research program to develop C1 chemistry processes to produce ultra-clean liquid transportation fuels and hydrogen, the zero-emissions transportation fuel of the future. The feedstocks contain one carbon atom per molecular unit. They include synthesis gas (syngas), a mixture of carbon monoxide and hydrogen produced by coal gasification or reforming of natural gas, methane, methanol, carbon dioxide, and carbon monoxide. An important objective is to develop C1 technology for the production of liquid transportation fuel and hydrogen from domestically plentiful resources such as coal, coalbed methane, and natural gas. An Industrial Advisory Board with representatives from Chevron-Texaco, Eastman Chemical, Conoco-Phillips, the Air Force Research Laboratory, the U.S. Army National Automotive Center (Tank & Automotive Command--TACOM), and Tier Associates provides guidance on the practicality of the research. The current report presents results obtained in this research program during the six months of the subject contract from October 1, 2002 through March 31, 2003. The results are presented in thirteen detailed reports on research projects headed by various faculty members at each of the five CFFS Universities. Additionally, an Executive Summary has been prepared that summarizes the principal results of all of these projects during the six-month reporting period.

  14. L-C1qDC-1, a novel C1q domain-containing protein from Lethenteron camtschaticum that is involved in the immune response.

    PubMed

    Pei, Guangying; Liu, Ge; Pan, Xiong; Pang, Yue; Li, Qingwei

    2016-01-01

    The C1q domain-containing (C1qDC) proteins are a family of proteins characterized by a globular C1q (gC1q) domain at their C-terminus. These proteins are involved in various processes in vertebrates and are assumed to serve as important pattern recognition receptors in innate immunity in invertebrates. Here, a novel C1qDC protein from Lethenteron camtschaticum was identified and characterized (designated as L-C1qDC-1). After a partial cDNA sequence of L-C1qDC-1 was identified in a L. camtschaticum liver cDNA library, the full-length cDNA was obtained using 3'- and 5'-rapid amplification of cDNA ends (RACE). L-C1qDC-1 encodes 236 amino acids and contains a signal peptide, a collagen-like sequence with Gly-Xaa-Yaa repeats, and a C-terminal gC1q domain. The L-C1qDC-1 protein was primarily distributed in the gut, liver and supraneural body of L. camtschaticum and was also marginally detectable in leukocytes via real-time PCR and immunofluorescence assays. Furthermore, both immunoprecipitation and immunofluorescence results showed that in L. camtschaticum serum, L-C1qDC-1 could interact with variable lymphocyte receptor (VLR) B and displayed strong colocalization with cancer cell immune responses. These results indicated that the L-C1qDC-1 gene encodes a novel C1qDC protein that may play an important role in the immune responses of L. camtschaticum, providing clues for understanding the universal functions of C1qDC proteins in other species and suggesting that these proteins could serve as pattern recognition molecules in immunotherapy. PMID:26342581

  15. Anatomic Consideration of the C1 Laminar Arch for Lateral Mass Screw Fixation via C1 Lateral Lamina : A Landmark between the Lateral and Posterior Lamina of the C1

    PubMed Central

    Kim, Jung-Hwan; Kwak, Dai-Soon; Han, Seung-Ho; Cho, Sung-Min; You, Seung-Hoon

    2013-01-01

    Objective To clarify the landmark for deciding the entry point for C1 lateral mass screws via the posterior arch by using 3-dimensional (3D) computed images. Methods Resnick insisted that the C1 posterior arch could be divided into pure posterior and lateral lamina (C1 pedicle). Authors studied where this transition point (TP) is located between the posterior lamina and the C1 pedicle and how it can be recognized. The 3D computed images of 86 cadaver C1s (M : F=45 : 41) were used in this study. Results The superior ridge of the C1 posterior arch had 2 types of orientation. One was in the vertical direction in the C1 posterior lamina and the other was in the horizontal direction in the C1 pedicle. The TP was located at the border between the 2 areas, the same site as the posterior end of the groove of the vertebral artery. On posterior-anterior projection, the posterior arch was sharpened abruptly at TP. We were unable to identify the TP in 6.4% of specimens due to complete or partial osseous bridges. A total of 93.8% of the TP were located between the most enlarged point of the spinal canal and the medial wall of the vertebral artery. Conclusion The anatomic entry zone of C1 lateral laminar screws was clarified and identified based on the TP by using preoperative 3D computed images. PMID:24044076

  16. Haploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms.

    PubMed

    Emadali, Anouk; Hoghoughi, Neda; Duley, Samuel; Hajmirza, Azadeh; Verhoeyen, Els; Cosset, Francois-Loic; Bertrand, Philippe; Roumier, Christophe; Roggy, Anne; Suchaud-Martin, Céline; Chauvet, Martine; Bertrand, Sarah; Hamaidia, Sieme; Rousseaux, Sophie; Josserand, Véronique; Charles, Julie; Templier, Isabelle; Maeda, Takahiro; Bruder-Costa, Juliana; Chaperot, Laurence; Plumas, Joel; Jacob, Marie-Christine; Bonnefoix, Thierry; Park, Sophie; Gressin, Remy; Tensen, Cornelis P; Mecucci, Cristina; Macintyre, Elizabeth; Leroux, Dominique; Brambilla, Elisabeth; Nguyen-Khac, Florence; Luquet, Isabelle; Penther, Dominique; Bastard, Christian; Jardin, Fabrice; Lefebvre, Christine; Garnache, Francine; Callanan, Mary B

    2016-06-16

    Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive leukemia for which knowledge on disease mechanisms and effective therapies are currently lacking. Only a handful of recurring genetic mutations have been identified and none is specific to BPDCN. In this study, through molecular cloning in an index case that presented a balanced t(3;5)(q21;q31) and molecular cytogenetic analyses in a further 46 cases, we identify monoallelic deletion of NR3C1 (5q31), encoding the glucocorticoid receptor (GCR), in 13 of 47 (28%) BPDCN patients. Targeted deep sequencing in 36 BPDCN cases, including 10 with NR3C1 deletion, did not reveal NR3C1 point mutations or indels. Haploinsufficiency for NR3C1 defined a subset of BPDCN with lowered GCR expression and extremely poor overall survival (P = .0006). Consistent with a role for GCR in tumor suppression, functional analyses coupled with gene expression profiling identified corticoresistance and loss-of-EZH2 function as major downstream consequences of NR3C1 deletion in BPDCN. Subsequently, more detailed analyses of the t(3;5)(q21;q31) revealed fusion of NR3C1 to a long noncoding RNA (lncRNA) gene (lincRNA-3q) that encodes a novel, nuclear, noncoding RNA involved in the regulation of leukemia stem cell programs and G1/S transition, via E2F. Overexpression of lincRNA-3q was a consistent feature of malignant cells and could be abrogated by bromodomain and extraterminal domain (BET) protein inhibition. Taken together, this work points to NR3C1 as a haploinsufficient tumor suppressor in a subset of BPDCN and identifies BET inhibition, acting at least partially via lncRNA blockade, as a novel treatment option in BPDCN. PMID:27060168

  17. Radiation damage of the HEAO C-1 germanium detectors

    NASA Technical Reports Server (NTRS)

    Mahoney, W. A.; Ling, J. C.; Jacobson, A. S.

    1981-01-01

    The effects of radiation damage from proton bombardment of the four HEAO C-1 high purity germanium detectors have been measured and compared to predictions. Because of the presence of numerous gamma-ray lines in the detector background spectra and because of the relatively long exposure time of the HEAO 3 satellite to cosmic-ray and trapped protons, it has been possible to measure both the energy and time dependence of radiation damage. After 100 d in orbit, each of the four detectors has been exposed to approximately 3 x 10 to the 7th protons/sq cm, and the average energy resolution at 1460 keV had degraded from 3.2 keV fwhm to 8.6 keV fwhm. The lines were all broadened to the low energy side although the line profile was different for each of the four detectors. The damage-related contribution to the degradation in energy resolution was found to be linear in energy and proton influence.

  18. Near-ultraviolet spectroscopy of Comet Austin (1989c1)

    NASA Technical Reports Server (NTRS)

    Valk, Jacobus H.; O'Dell, C. R.; Cochran, Anita L.; Cochran, William D.; Opal, Chet B. S.; Barker, Edwin S.

    1992-01-01

    Comet Austin (1989c1) was observed post-perihelion at a heliocentric distance near 1.25 AU. The wavelength range was from the atmospheric cutoff at 3000 to 4000 A. The coma spectra were calibrated into flux units and the contaminating sky spectrum and solar scattered light continuum were subtracted, leaving an ultraviolet spectrum of about 1.5-A resolution and excellent signal-to-noise ratio. The spectrum is dominated by emissions from OH, NH, CH, C3, and CN, some of the weaker emissions of which are seen here for the first time. More bands of CO(2+) were found than in any previous investigation and several intensity anomalies were noted; H2CO, OH(+), NCN, N(2+), and CN(+) may be present. Several emission features well above the noise level remain unidentified. The relative intensities of the OH and CN bands agree with the predictions of resonance fluorescence when one considers the potential effects of contamination by other molecules. The effects of the ozone absorption spectrum are not fully removed by the data-reduction process, although this does not affect these results.

  19. Structure of human Niemann-Pick C1 protein.

    PubMed

    Li, Xiaochun; Wang, Jiawei; Coutavas, Elias; Shi, Hang; Hao, Qi; Blobel, Günter

    2016-07-19

    Niemann-Pick C1 protein (NPC1) is a late-endosomal membrane protein involved in trafficking of LDL-derived cholesterol, Niemann-Pick disease type C, and Ebola virus infection. NPC1 contains 13 transmembrane segments (TMs), five of which are thought to represent a "sterol-sensing domain" (SSD). Although present also in other key regulatory proteins of cholesterol biosynthesis, uptake, and signaling, the structure and mechanism of action of the SSD are unknown. Here we report a crystal structure of a large fragment of human NPC1 at 3.6 Å resolution, which reveals internal twofold pseudosymmetry along TM 2-13 and two structurally homologous domains that protrude 60 Å into the endosomal lumen. Strikingly, NPC1's SSD forms a cavity that is accessible from both the luminal bilayer leaflet and the endosomal lumen; computational modeling suggests that this cavity is large enough to accommodate one cholesterol molecule. We propose a model for NPC1 function in cholesterol sensing and transport. PMID:27307437

  20. Structure of human Niemann–Pick C1 protein

    PubMed Central

    Li, Xiaochun; Wang, Jiawei; Coutavas, Elias; Shi, Hang; Hao, Qi; Blobel, Günter

    2016-01-01

    Niemann–Pick C1 protein (NPC1) is a late-endosomal membrane protein involved in trafficking of LDL-derived cholesterol, Niemann–Pick disease type C, and Ebola virus infection. NPC1 contains 13 transmembrane segments (TMs), five of which are thought to represent a “sterol-sensing domain” (SSD). Although present also in other key regulatory proteins of cholesterol biosynthesis, uptake, and signaling, the structure and mechanism of action of the SSD are unknown. Here we report a crystal structure of a large fragment of human NPC1 at 3.6 Å resolution, which reveals internal twofold pseudosymmetry along TM 2–13 and two structurally homologous domains that protrude 60 Å into the endosomal lumen. Strikingly, NPC1's SSD forms a cavity that is accessible from both the luminal bilayer leaflet and the endosomal lumen; computational modeling suggests that this cavity is large enough to accommodate one cholesterol molecule. We propose a model for NPC1 function in cholesterol sensing and transport. PMID:27307437

  1. Passageway: A Novel Approach to Success of Conditional Release - Principles and Constructs of the Model Residential Program for the Forensic Mentally III Patient.

    PubMed

    Melnick, Ilan

    2016-03-01

    With the advent of psychotropic medications and with the deinstitutionalization of psychiatry starting in 1968, patients were prematurely discharged from forensic state hospitals. Due to lack of resources, psychiatric forensic patients ended up in the correctional system or homeless with the reduction of psychiatric beds in forensic and civil state hospitals. Lacking proper training and medication management, the recidivism rate of this population was close to 10% for rearrest and about 35% for revocation of conditional release (CR; Manguno-Mire et al., ). A new treatment modality was created to successfully transition patients from the forensic state hospital system to the community. This article describes and analyzes the principles and constructs of Passageway, a model residential program for patients found not guilty by reason of insanity or those incompetent to proceed to CR. The CR allows for a program like Passageway to be successful in transitioning patients back into the community. This is accomplished with minimal government funding, and since 1982 has resulted in a 0% recidivism rate, for any known arrests or convictions and for recommittal of a felony, defined in the state of Florida as, "any criminal offense that is punishable under the laws of this state, or that would be punishable, if committed in this state, by death or imprisonment in a state penitentiary. " (Fla. Stat. § 775.08). Copyright © 2016 John Wiley & Sons, Ltd. PMID:27097984

  2. Preliminary design data package, appendices C1 and C2

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The HYBRID2 program which computes the fuel and energy consumption of a hybrid vehicle with a bi-modal control strategy over specified component driving cycles is described. Fuel and energy consumption are computed separately for the two modes of operation. The program also computes yearly average fuel and energy consumption using a composite driving cycle which varies as a function of daily travel. The modelling techniques are described, and subroutines and their functions are given. The composition of modern automobiles is discussed along with the energy required to manufacture an American automobile. The energy required to scrap and recycle automobiles is also discussed.

  3. Construction & Basic Skills.

    ERIC Educational Resources Information Center

    BCEL Newsletter for the Business and Literacy Communities, 1991

    1991-01-01

    Basic skills education has become a pressing need in the construction industry as jobs become more complex and fewer workers have needed skills. However, the construction industry lags in spending on training for entry-level workers. The Home Builders Institute (HBI) is testing a pilot basic skills program that it hopes will prove useful to the…

  4. Construction Print Reading.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    Developed as part of the Marine Corps Institute (MCI) correspondence training program, this course on construction print reading is designed to provide Marines of all ranks and Military Occupation Specialities with the basic information to recognize the terms and symbols used in construction prints; it is adaptable for nonmilitary instruction.…

  5. THE EFFECTS OF EMBRYONIC KNOCKDOWN OF THE CANDIDATE DYSLEXIA SUSCEPTIBILITY GENE HOMOLOGUE DYX1C1 ON THE DISTRIBUTION OF GABAERGIC NEURONS IN THE CEREBRAL CORTEX

    PubMed Central

    Currier, Timothy A.; Etchegaray, Mikel A.; Haight, Joshua L.; Galaburda, Albert M.; Rosen, Glenn D.

    2010-01-01

    Developmental dyslexia is a language-based learning disability, and a number of candidate dyslexia susceptibility genes have been identified, including DYX1C1, KIAA0319, and DCDC2. Knockdown of function by embryonic transfection of small hairpin RNA (shRNA) of rat homologues of these genes dramatically disrupts neuronal migration to the cerebral cortex by both cell autonomous and non-cell autonomous effects. Here we sought to investigate the extent of non-cell autonomous effects following in utero disruption of the candidate dyslexia susceptibility gene homolog Dyx1c1 by assessing the effects of this disruption on GABAergic neurons. We transfected the ventricular zone of embryonic day (E) 15.5 rat pups with either Dyx1c1 shRNA, DYX1C1 expression construct, both Dyx1c1 shRNA and DYX1C1 expression construct, or a scrambled version of Dyx1c1 shRNA, and sacrificed them at postnatal day 21. The mothers of these rats were injected with BrdU at either E13.5, E15.5, or E17.5. Neurons transfected with Dyx1c1 shRNA were bi-modally distributed in the cerebral cortex with one population in heterotopic locations at the white matter border and another migrating beyond their expected location in the cerebral cortex. In contrast, there was no disruption of migration following transfection with the DYX1C1 expression construct. We found untransfected GABAergic neurons (parvalbumin, calretinin, and neuropeptide Y) in the heterotopic collections of neurons in Dyx1c1 shRNA treated animals, supporting the hypothesis of non-cell autonomous effects. In contrast, we found no evidence that the position of the GABAergic neurons that made it to the cerebral cortex was disrupted by the embryonic transfection with any of the constructs. Taken together, these results support the notion that neurons within heterotopias caused by transfection with Dyx1c1 shRNA result from both cell autonomous and non-cell autonomous effects, but there is no evidence to support non-cell autonomous disruption of

  6. A common neoepitope is created when the reactive center of C1-inhibitor is cleaved by plasma kallikrein, activated factor XII fragment, C1 esterase, or neutrophil elastase.

    PubMed Central

    de Agostini, A; Patston, P A; Marottoli, V; Carrel, S; Harpel, P C; Schapira, M

    1988-01-01

    The reactive center of C1-inhibitor, a plasma protease inhibitor that belongs to the serpin superfamily, is located on a peptide loop which is highly susceptible to proteolytic cleavage. With plasma kallikrein, C1s and beta-Factor XIIa, this cleavage occurs at the reactive site residue P1 (Arg444); with neutrophil elastase, it takes place near P1, probably at residue P3 (Val442). After these cleavages, C1-inhibitor is inactivated and its conformation is modified. Moreover, in vivo, cleaved C1-inhibitor is removed from the blood stream more rapidly than the intact serpin, which suggests that proteolysis unmasks sites responsible for cellular recognition and the uptake of the cleaved inhibitor. In the study reported here, we show, using an MAb, that an identical neoepitope is created on C1-inhibitor after the cleavage of its exposed loop by plasma kallikrein, C1s, beta-Factor XIIa, and by neutrophil elastase. Images PMID:2457036

  7. Self-assembly of Carbon Vacancies in Sub-stoichiometric ZrC1−x

    PubMed Central

    Zhang, Yanhui; Liu, Bin; Wang, Jingyang

    2015-01-01

    Sub-stoichiometric interstitial compounds, including binary transition metal carbides (MC1−x), maintain structural stability even if they accommodate abundant anion vacancies. This unique character endows them with variable-composition, diverse-configuration and controllable-performance through composition and structure design. Herein, the evolution of carbon vacancy (VC) configuration in sub-stoichiometric ZrC1−x is investigated by combining the cluster expansion method and first-principles calculations. We report the interesting self-assembly of VCs and the fingerprint VC configuration (VC triplet constructed by 3rd nearest neighboring vacancies) in all the low energy structures of ZrC1−x. When VC concentration is higher than the critical value of 0.5 (x > 0.5), the 2nd nearest neighboring VC configurations with strongly repulsive interaction inevitably appear, and meanwhile, the system energy (or formation enthalpy) of ZrC1−x increases sharply which suggests the material may lose phase stability. The present results clarify why ZrC1−x bears a huge amount of VCs, tends towards VC ordering, and retains stability up to a stoichiometry of x = 0.5. PMID:26667083

  8. [Hereditary angioneurotic edema: a molecular disease caused by a defect in the O-glycosylation of C1 esterase inhibitor (C1-INH)].

    PubMed

    Ollier-Hartmann, M P; Strecker, G; Montreuil, J; Hartmann, L

    1984-01-01

    A quantitative and qualitative study of neutral and aminosaccharides in C 1-esterase inhibitor (C 1-INH), protein of the complement system, was performed. We observe a mixed glycosylation of the molecule with an N-glycosylated: O-glycosylated chain ratio of 1: 4. The loss of the inhibitory activity of the molecule in hereditary angioedema (O ANH) is associated with an O-glycosylation deficiency which differs according to the two molecular variants: C 1-INH (1 A) and C 1-INH (II) previously described. PMID:6440668

  9. Construction aggregates

    USGS Publications Warehouse

    Tepordei, V.V.

    1995-01-01

    Part of the 1994 Industrial Minerals Review. The production, consumption, and applications of construction aggregates are reviewed. In 1994, the production of construction aggregates, which includes crushed stone and construction sand and gravel combined, increased 7.7 percent to 2.14 Gt compared with the previous year. These record production levels are mostly a result of funding for highway construction work provided by the Intermodal Surface Transportation Efficiency Act of 1991. Demand is expected to increase for construction aggregates in 1995.

  10. In silico structural characteristics and α-amylase inhibitory properties of Ric c 1 and Ric c 3, allergenic 2S albumins from Ricinus communis seeds.

    PubMed

    Do Nascimento, Viviane Veiga; Castro, Helena Carla; Abreu, Paula Alvarez; Oliveira, Antônia Elenir Amâncio; Fernandez, Jorge Hernandez; Araújo, Jucélia Da Silva; Machado, Olga Lima Tavares

    2011-05-11

    The major Ricinus communis allergens are the 2S albumins, Ric c 1 and Ric c 3. These proteins contain a trypsin/α-amylase inhibitor family domain, suggesting that they have a role in insect resistance. In this study, we verified that Ric c 1 and Ric c 3 inhibited the α-amylase activity of Callosobruchus maculatus, Zabrotes subfasciatus, and Tenebrio molitor (TMA) larvae as well as mammalian α-amylase. The toxicity of 2S albumin was determined through its incorporation in C. maculatus larvae as part of an artificial diet. Bioassays revealed that 2S albumin reduced larval growth by 20%. We also analyzed the tridimensional structures of Ric c 1 and Ric c 3 by (a) constructing a comparative model of Ric c 1 based on Ric c 3 NMR structure and (b) constructing the theoretical structure of the Ric c 1-TMA and Ric c 3-TMA complexes. Our biological and theoretical results revealed that Ric c 1 and Ric c 3 are a new class of α-amylase inhibitors. They could potentially be used to help design inhibitors that would be useful in diverse fields, ranging from diabetes treatment to crop protection. PMID:21425874

  11. C1 CHEMISTRY FOR THE PRODUCTION OF ULTRA-CLEAN LIQUID TRANSPORTATION FUELS AND HYDROGEN

    SciTech Connect

    Gerald P. Huffman

    2004-09-30

    The Consortium for Fossil Fuel Science (CFFS) is a research consortium with participants from the University of Kentucky, University of Pittsburgh, West Virginia University, University of Utah, and Auburn University. The CFFS is conducting a research program to develop C1 chemistry technology for the production of clean transportation fuel from resources such as coal and natural gas, which are more plentiful domestically than petroleum. The processes under development will convert feedstocks containing one carbon atom per molecular unit into ultra clean liquid transportation fuels (gasoline, diesel, and jet fuel) and hydrogen, which many believe will be the transportation fuel of the future. Feedstocks include synthesis gas, a mixture of carbon monoxide and hydrogen produced by coal gasification, coalbed methane, light products produced by Fischer-Tropsch (FT) synthesis, methanol, and natural gas.

  12. Human diploid fibroblasts have receptors for the globular domain of C1Q

    SciTech Connect

    Bordin, S.; Page, R.C.

    1986-03-01

    The authors showed that mass cultures of fibroblasts grown from gingival explants in DB medium with 10% human serum are enriched in a phenotype that binds C1q with an affinity much higher than the rest of the population. Because of potential biologic importance of C1q receptors, the authors studied whether the interaction between C1q and this phenotype was mediated by the globular or collagenous domains of the molecule. Globular fragments were prepared by digesting C1q with collagenase, and collagenous fragments obtained after pepsin treatment. C1q binding on cells in suspension was determined by reaction with /sup 125/I-C1q as reported. Competition experiments were performed under conditions in which intact /sup 125/I-C1q binding saturated all available receptors. The results showed that collagenous fragments inhibited 20% of the /sup 125/I-C1q binding to high affinity receptors, whereas inhibition by globular fragments was 70%. Unlabeled intact C1q and collagen type 1 were used as controls, and inhibited 92% and 17% of C1q binding, respectively. These studies show that C1q interacts with the fibroblast phenotype expressing high affinity receptors through its globular domain. The authors suggest that at sites of trauma, native C1 may bind to the surface of these cells via the globular domain of C1q, and that this unique phenotype may play an important role in tissue repair.

  13. Aviation Safety Modeling and Simulation (ASMM) Propulsion Fleet Modeling: A Tool for Semi-Automatic Construction of CORBA-based Applications from Legacy Fortran Programs

    NASA Technical Reports Server (NTRS)

    Sang, Janche

    2003-01-01

    Within NASA's Aviation Safety Program, NASA GRC participates in the Modeling and Simulation Project called ASMM. NASA GRC s focus is to characterize the propulsion systems performance from a fleet management and maintenance perspective by modeling and through simulation predict the characteristics of two classes of commercial engines (CFM56 and GE90). In prior years, the High Performance Computing and Communication (HPCC) program funded, NASA Glenn in developing a large scale, detailed simulations for the analysis and design of aircraft engines called the Numerical Propulsion System Simulation (NPSS). Three major aspects of this modeling included the integration of different engine components, coupling of multiple disciplines, and engine component zooming at appropriate level fidelity, require relatively tight coupling of different analysis codes. Most of these codes in aerodynamics and solid mechanics are written in Fortran. Refitting these legacy Fortran codes with distributed objects can increase these codes reusability. Aviation Safety s modeling and simulation use in characterizing fleet management has similar needs. The modeling and simulation of these propulsion systems use existing Fortran and C codes that are instrumental in determining the performance of the fleet. The research centers on building a CORBA-based development environment for programmers to easily wrap and couple legacy Fortran codes. This environment consists of a C++ wrapper library to hide the details of CORBA and an efficient remote variable scheme to facilitate data exchange between the client and the server model. Additionally, a Web Service model should also be constructed for evaluation of this technology s use over the next two- three years.

  14. Molecular Determinants of the Substrate Specificity of the Complement-initiating Protease, C1r*

    PubMed Central

    Wijeyewickrema, Lakshmi C.; Yongqing, Tang; Tran, Thuy P.; Thompson, Phillip E.; Viljoen, Jacqueline E.; Coetzer, Theresa H.; Duncan, Renee C.; Kass, Itamar; Buckle, Ashley M.; Pike, Robert N.

    2013-01-01

    The serine protease, C1r, initiates activation of the classical pathway of complement, which is a crucial innate defense mechanism against pathogens and altered-self cells. C1r both autoactivates and subsequently cleaves and activates C1s. Because complement is implicated in many inflammatory diseases, an understanding of the interaction between C1r and its target substrates is required for the design of effective inhibitors of complement activation. Examination of the active site specificity of C1r using phage library technology revealed clear specificity for Gln at P2 and Ile at P1′, which are found in these positions in physiological substrates of C1r. Removal of one or both of the Gln at P2 and Ile at P1′ in the C1s substrate reduced the rate of C1r activation. Substituting a Gln residue into the P2 of the activation site of MASP-3, a protein with similar domain structure to C1s that is not normally cleaved by C1r, enabled efficient activation of this enzyme. Molecular dynamics simulations and structural modeling of the interaction of the C1s activation peptide with the active site of C1r revealed the molecular mechanisms that particularly underpin the specificity of the enzyme for the P2 Gln residue. The complement control protein domains of C1r also made important contributions to efficient activation of C1s by this enzyme, indicating that exosite interactions were also important. These data show that C1r specificity is well suited to its cleavage targets and that efficient cleavage of C1s is achieved through both active site and exosite contributions. PMID:23589288

  15. Preface: phys. stat. sol. (c) 1/9

    NASA Astrophysics Data System (ADS)

    Leitch, Andrew; Botha, Reinhardt

    2004-08-01

    The Conference on Photo-responsive Materials took place at the Kariega Game Reserve in the Eastern Cape, South Africa from 25-29 February 2004. More than 60 delegates from 12 different countries participated in the four-day event.The purpose of the conference was to bring together scientists working on various aspects of photo-responsive materials, so as to stimulate this important field of solid state physics in Southern Africa. As may be seen from the list of papers appearing in these proceedings, there was much interest in copper indium diselenide as a thin film material for photovoltaic applications. Also worth mentioning were the valuable contributions on ZnO, GaN and other materials that are currently attracting attention worldwide.The conference program allowed sufficient time for interaction and exchanging of views. Being in a game reserve in the heart of the beautiful Eastern Cape, delegates were also taken on game drives and had the opportunity of taking a river cruise up the Kariega River to view the majestic fish eagle.The members of the academic program committee were: Vivian Alberts (Rand Afrikaans University), Danie Auret (University of Pretoria), Darrell Comins (University of the Witwatersrand), and Reinhardt Botha and Andrew Leitch (University of Port E All papers appearing in these proceedings underwent a strict reviewing process separate from the conference. We express our appreciation to the referees for their diligence in this important task. The conference was organized by the Department of Physics at the University of Port Elizabeth, under the auspices of the Condensed Matter Physics and Materials Science (CMPMS) subgroup of the South African Institute of Physics. It was sponsored by EMF Limited (UK), Sensors Unlimited Inc. (USA), and Carl Zeiss (Pty) Ltd. Special thanks must go to Dr Eunete van Wyk for her professional assistance in the preparation of these proceedings.

  16. Studies on human plasma C1 inactivator-enzyme interactions. I. Mechanisms of interaction with C1s, plasmin, and trypsin.

    PubMed Central

    Harpel, P C; Cooper, N R

    1975-01-01

    This study has explored the nature of the molecular events which occur when C1 inactivator, a human plasma inhibitor of the complement, kinin-forming, coagulation, and fibrinolytic enzyme systems, interacts with C1s, plasmin, and trypsin. Purified inhibitor preparations demonstrated two bands, when examined by acrylamide gel electrophoresis in the presence of sodium dodecyl sulfate (SDS). The molecular weights of the major and minor bands were 105,000 and 96,000 daltons, respectively. The minor component appeared to be immunologically and functionally identical to the main C1 inactivator component. Loss of C1s and plasmin functional activity was associated with the formation of a 1:1 molar complex between the inhibitor and each enzyme. These complexes were stable in the presence of SDS and urea. The light chain of both these enzymes provided the binding site for C1 inactivator. Complex formation and enzyme inhibition occurred only with native and not with an inhibitor preparation denatured by acid treatment, thereby demonstrating the importance of conformational factors in the enzyme-inhibitor reaction. Although peptide bond cleavage of the C1 inactivator molecule by C1s was not documented, plasmin was found to degrade the inhibitor with the production of several characteristic derivatives. At least one of these products retained the ability to complex with C1s and plasmin. Trypsin, which failed to form a complex with C1 inactivator, degraded the inhibitor in a limited and sequential manner with the production of nonfunctional derivatives one of which appeared structurally similar to a plasmin-induced product. These studies therefore, provide new information concerning the molecular interactions between C1 inactivator and several of the proteases which it inhibits. Images PMID:123251

  17. 26 CFR 31.3302(c)-1 - Limit on total credits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 15 2011-04-01 2011-04-01 false Limit on total credits. 31.3302(c)-1 Section 31.3302(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) EMPLOYMENT... Federal Unemployment Tax Act (Chapter 23, Internal Revenue Code of 1954) § 31.3302(c)-1 Limit on...

  18. 26 CFR 1.666(c)-1A - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Pro rata portion of taxes deemed distributed. 1.666(c)-1A Section 1.666(c)-1A Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1A Pro rata portion of taxes deemed...

  19. 26 CFR 1.666(c)-1 - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Pro rata portion of taxes deemed distributed. 1.666(c)-1 Section 1.666(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1 Pro rata portion of taxes deemed...

  20. 17 CFR 270.18c-1 - Exemption of privately held indebtedness.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption of privately held indebtedness. 270.18c-1 Section 270.18c-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) RULES AND REGULATIONS, INVESTMENT COMPANY ACT OF 1940 § 270.18c-1 Exemption of privately held indebtedness. The issuance or...

  1. 26 CFR 1.503(c)-1 - Future status of organizations denied exemption.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 7 2014-04-01 2013-04-01 true Future status of organizations denied exemption. 1.503(c)-1 Section 1.503(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.503(c)-1 Future status of organizations denied exemption. (a)...

  2. 26 CFR 1.666(c)-1 - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ....666(c)-1 Section 1.666(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Applicable to Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1 Pro rata portion of taxes deemed distributed. (a) If an accumulation distribution is deemed under § 1.666(a)-1 to be distributed on the...

  3. 26 CFR 1.666(c)-1A - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ....666(c)-1A Section 1.666(c)-1A Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Applicable to Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1A Pro rata portion of taxes deemed distributed. (a) If an accumulation distribution is deemed under § 1.666(a)-1A to be distributed on the...

  4. 26 CFR 1.673(c)-1 - Reversionary interest after income beneficiary's death.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 8 2012-04-01 2012-04-01 false Reversionary interest after income beneficiary's death. 1.673(c)-1 Section 1.673(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... Substantial Owners § 1.673(c)-1 Reversionary interest after income beneficiary's death. The subject matter...

  5. 26 CFR 1.673(c)-1 - Reversionary interest after income beneficiary's death.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 8 2014-04-01 2014-04-01 false Reversionary interest after income beneficiary's death. 1.673(c)-1 Section 1.673(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... Substantial Owners § 1.673(c)-1 Reversionary interest after income beneficiary's death. The subject matter...

  6. 26 CFR 1.673(c)-1 - Reversionary interest after income beneficiary's death.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Reversionary interest after income beneficiary's death. 1.673(c)-1 Section 1.673(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... Substantial Owners § 1.673(c)-1 Reversionary interest after income beneficiary's death. The subject matter...

  7. 26 CFR 1.509(c)-1 - Status of organization after termination of private foundation status.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... private foundation status. 1.509(c)-1 Section 1.509(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(c)-1 Status of organization after termination of private foundation status. (a) In...

  8. 26 CFR 1.509(c)-1 - Status of organization after termination of private foundation status.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... private foundation status. 1.509(c)-1 Section 1.509(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(c)-1 Status of organization after termination of private foundation status. (a) In...

  9. 26 CFR 1.509(c)-1 - Status of organization after termination of private foundation status.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... private foundation status. 1.509(c)-1 Section 1.509(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(c)-1 Status of organization after termination of private foundation status. (a) In...

  10. 26 CFR 1.509(c)-1 - Status of organization after termination of private foundation status.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... private foundation status. 1.509(c)-1 Section 1.509(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Private Foundations § 1.509(c)-1 Status of organization after termination of private foundation status. (a) In...

  11. 26 CFR 1.1244(c)-1 - Section 1244 stock defined.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 11 2014-04-01 2014-04-01 false Section 1244 stock defined. 1.1244(c)-1 Section 1.1244(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Special Rules for Determining Capital Gains and Losses § 1.1244(c)-1 Section 1244 stock defined. (a)...

  12. 26 CFR 1.503(c)-1 - Future status of organizations denied exemption.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Future status of organizations denied exemption. 1.503(c)-1 Section 1.503(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.503(c)-1 Future...

  13. 26 CFR 1.503(c)-1 - Future status of organizations denied exemption.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 7 2012-04-01 2012-04-01 false Future status of organizations denied exemption. 1.503(c)-1 Section 1.503(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.503(c)-1 Future...

  14. 26 CFR 1.503(c)-1 - Future status of organizations denied exemption.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 7 2013-04-01 2013-04-01 false Future status of organizations denied exemption. 1.503(c)-1 Section 1.503(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.503(c)-1 Future...

  15. 26 CFR 1.860C-1 - Taxation of holders of residual interests.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Taxation of holders of residual interests. 1.860C-1 Section 1.860C-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Real Estate Investment Trusts § 1.860C-1 Taxation of...

  16. 26 CFR 1.666(c)-1A - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....666(c)-1A Section 1.666(c)-1A Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Applicable to Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1A Pro rata portion of taxes deemed distributed. (a) If an accumulation distribution is deemed under § 1.666(a)-1A to be distributed on the...

  17. 26 CFR 1.666(c)-1 - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ....666(c)-1 Section 1.666(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Applicable to Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1 Pro rata portion of taxes deemed distributed. (a) If an accumulation distribution is deemed under § 1.666(a)-1 to be distributed on the...

  18. 26 CFR 1.666(c)-1A - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....666(c)-1A Section 1.666(c)-1A Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Applicable to Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1A Pro rata portion of taxes deemed distributed. (a) If an accumulation distribution is deemed under § 1.666(a)-1A to be distributed on the...

  19. 26 CFR 1.666(c)-1A - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ....666(c)-1A Section 1.666(c)-1A Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Applicable to Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1A Pro rata portion of taxes deemed distributed. (a) If an accumulation distribution is deemed under § 1.666(a)-1A to be distributed on the...

  20. 26 CFR 1.666(c)-1 - Pro rata portion of taxes deemed distributed.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....666(c)-1 Section 1.666(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Applicable to Taxable Years Beginning Before January 1, 1969 § 1.666(c)-1 Pro rata portion of taxes deemed distributed. (a) If an accumulation distribution is deemed under § 1.666(a)-1 to be distributed on the...