Science.gov

Sample records for correlation length measurements

  1. Measurement of surface roughness and correlation length using dichromatic speckle

    NASA Astrophysics Data System (ADS)

    Deka, M.

    1980-03-01

    A computer simulation study of the dichromatic speckle was conducted and the surface roughness and correlation length of sample surfaces were measured using a stylus instrument and similar measurements with dichromatic speckle. The rms difference of the two speckle intensities was analyzed for spot sizes smaller than, comparable and larger than the correlation length of the surface. The rms roughness of the sample ground glasses was calculated from the data obtained from the stylus instrument. The correlation length was obtained from an online multichannel FFT processor connected to the stylus instrument. The correlation length was estimated from the correlation function. The rms difference between the speckle intensities of two different wavelengths were measured for various spot sizes. For each intensity 64 K data samples was collected and processed in a PDP 11/40 computer. These data were used to calculate the second moment of the monochromatic speckle, the cross correlation of these and the rms difference. The roughness and the correlation length of the surface were estimated from these results. The results obtained from the dichromatic speckle are in good agreement with the values obtained from the stylus instrument.

  2. Bunch Length Measurements With Laser/SR Cross-Correlation

    SciTech Connect

    Miller, Timothy; Daranciang, Dan; Lindenberg, Aaron; Corbett, Jeff; Fisher, Alan; Goodfellow, John; Huang, Xiaobiao; Mok, Walter; Safranek, James; Wen, Haidan; /SLAC

    2012-07-06

    By operating SPEAR3 in low-{alpha} mode the storage ring can generate synchrotron radiation pulses of order 1ps. Applications include pump-probe x-ray science and the production of THz radiation in the CSR regime. Measurements of the bunch length are difficult, however, because the light intensity is low and streak cameras typically provide resolution of only a few ps. Tests are now underway to resolve the short bunch length using cross-correlation between a 60-fs Ti:Sapphire laser and the visible SR beam in a BBO crystal. In this paper we report on the experimental setup, preliminary measurements and prospects for further improvement.

  3. Measurement of the Correlation and Coherence Lengths in Boundary Layer Flight Data

    NASA Technical Reports Server (NTRS)

    Palumbo, Daniel L.

    2011-01-01

    Wall pressure data acquired during flight tests at several flight conditions are analyzed and the correlation and coherence lengths of the data reported. It is shown how the frequency bandwidth of the analysis biases the correlation length and how the convection of the flow acts to reduce the coherence length. Coherence lengths measured in the streamwise direction appear much longer than would be expected based on classical results for flow over a flat plat.

  4. Light-scattering measurement of the nematic correlation length in a liquid crystal with quenched disorder

    NASA Astrophysics Data System (ADS)

    Bellini, Tommaso; Clark, Noel A.; Degiorgio, Vittorio; Mantegazza, Francesco; Natale, Giorgio

    1998-03-01

    We have studied a composite system formed by a nematic thermotropic liquid crystal in which small silica particles have been dispersed. The colloids are aggregated and exert a randomizing effect on the nematic structure. The distorted pattern of the optical axis gives rise to a strong optical turbidity τ. We have measured τ as a function of the silica concentration Φ and of the temperature T in both the isotropic and nematic phase. We have found that, at fixed T, τ has a maximum as a function of Φ, and that, upon changing Φ, the whole shape of τ(T) drastically transforms. We have devised a model to describe the scattering of light from a distorted uniaxial system. The model has been developed both in the Born approximation and in the anomalous diffraction approximation, the two regimes which cover the broad range of experimental conditions. The family of τ(T) curves experimentally obtained at different Φ's is remarkably well described by the theoretical model, using as the only fitting parameter the correlation length ζ. We have found that, upon decreasing Φ, the nematic correlation length diverges as a power law of Φ. We compare the exponent of the power law with the prediction of the Imry-Ma theory of phase behavior in disordered systems, and we discuss the connection between ζ and the fractal correlation length of the silica aggregates.

  5. Generating synthetic 3D density fluctuation data to verify two-point measurement of parallel correlation length

    NASA Astrophysics Data System (ADS)

    Kim, Jaewook; Ghim, Young-Chul; Nuclear Fusion and Plasma Lab Team

    2014-10-01

    A BES (beam emission spectroscopy) system and an MIR (Microwave Imaging Reflectometer) system installed in KSTAR measure 2D (radial and poloidal) density fluctuations at two different toroidal locations. This gives a possibility of measuring the parallel correlation length of ion-scale turbulence in KSTAR. Due to lack of measurement points in toroidal direction and shorter separation distance between the diagnostics compared to an expected parallel correlation length, it is necessary to confirm whether a conventional statistical method, i.e., using a cross-correlation function, is valid for measuring the parallel correlation length. For this reason, we generated synthetic 3D density fluctuation data following Gaussian random field in a toroidal coordinate system that mimic real density fluctuation data. We measure the correlation length of the synthetic data by fitting a Gaussian function to the cross-correlation function. We observe that there is disagreement between the measured and actual correlation lengths, and the degree of disagreement is a function of at least, correlation length, correlation time and advection velocity of synthetic data. We identify the cause of disagreement and propose an appropriate method to measure correct correlation length.

  6. Combined measurements of modulus and length and their correlation for different amorphous alloys

    SciTech Connect

    Porscha, B.; Neuhaeuser, H.

    1995-03-15

    Combined measurements of length and modulus change on the same specimen of Ni{sub 78}Si{sub 8}B{sub 14}, Cu{sub 64}Ti{sub 36} and Co{sub 66}Fe{sub 4}(MoSiB){sub 30} are presented. These properties are sensitive to different aspects of structural changes during relaxation in the amorphous state. The change of length is mainly sensitive to the topological long range relaxation. The change of the eigenfrequency is mainly sensitive to atomic rearrangements changing the chemical short range order. The results of the correlation between the effect of relaxation of frequency versus that of length can be described as follows: the observed structural relaxation in the amorphous states of each material can be divided up into two regimes. The first regime (I) with a prevailing change of eigenfrequency is attributed to short range rearrangements of the chemically different atomic species in the material; the second regime (II) with a larger amount of length change is interpreted as a long range topological relaxation with enhanced loss of free volume. This interpretation is supported by a comparison of the diffusion coefficients at the characteristic transition temperature {Tc} between the regimes I and II. It shows that the average diffusion path lengths of the possible diffusors below the characteristic temperature are in the order of 2 to 5 next neighbor distances, i.e., diffusion is only possible in a short range changing the species of neighboring atoms. Above {Tc}, the average diffusion path lengths are in the order of 5 to 50 next neighbor distances suggesting long range relaxation rearrangements by a diffusion process preferentially connected with the annihilation of free volume.

  7. Picosecond Bunch length and Energy-z correlation measurements at SLAC's A-Line and End Station A

    SciTech Connect

    Molloy, Stephen; Emma, P.; Frisch, J.C.; Iverson, R.H.; Ross, M.; McCormick, D.J.; Ross, Marc C.; Walston, S.; Blackmore, V.; /Oxford U.

    2007-06-27

    We report on measurements of picosecond bunch lengths and the energy-z correlation of the bunch with a high energy electron test beam to the A-line and End Station A (ESA) facilities at SLAC. The bunch length and the energy-z correlation of the bunch are measured at the end of the linac using a synchrotron light monitor diagnostic at a high dispersion point in the A-line and a transverse RF deflecting cavity at the end of the linac. Measurements of the bunch length in ESA were made using high frequency diodes (up to 100 GHz) and pyroelectric detectors at a ceramic gap in the beamline. Modeling of the beam's longitudinal phase space through the linac and A-line to ESA is done using the 2-dimensional tracking program LiTrack, and LiTrack simulation results are compared with data. High frequency diode and pyroelectric detectors are planned to be used as part of a bunch length feedback system for the LCLS FEL at SLAC. The LCLS also plans precise bunch length and energy-z correlation measurements using transverse RF deflecting cavities.

  8. Large-amplitude magnetic variations in quasi-parallel shocks - Correlation lengths measured by ISEE 1 and 2

    NASA Technical Reports Server (NTRS)

    Greenstadt, E. W.; Hoppe, M. M.; Russell, C. T.

    1982-01-01

    Wide separations up to more than 1 earth radius between ISEE 1 and 2 during the second half of 1978 have been used to measure the correlation length of magnetic pulsations in quasiparallel shocks. When the two spacecraft were less than a few hundred km apart, magnetic oscillations measured by magnetometers on both spacecraft exhibited virtually identical waveforms, but at distances of several thousand km, the two time series of field variation showed no detailed similarily at all. The correlation coefficients of the pulsations dropped from close to 1.0 for spacecraft separations of less than 100 km to 0.2 for separations of greater than 800 km. A correlation length of several hundred km may be related to the gyroradius of return protons with energy typical of the peaks of diffuse and beam ion distributions.

  9. Measuring Thermodynamic Length

    SciTech Connect

    Crooks, Gavin E

    2007-09-07

    Thermodynamic length is a metric distance between equilibrium thermodynamic states. Among other interesting properties, this metric asymptotically bounds the dissipation induced by a finite time transformation of a thermodynamic system. It is also connected to the Jensen-Shannon divergence, Fisher information, and Rao's entropy differential metric. Therefore, thermodynamic length is of central interestin understanding matter out of equilibrium. In this Letter, we will consider how to denethermodynamic length for a small system described by equilibrium statistical mechanics and how to measure thermodynamic length within a computer simulation. Surprisingly, Bennett's classic acceptance ratio method for measuring free energy differences also measures thermodynamic length.

  10. Spatial and temporal correlation length as a measure for the stationarity of atmospheric dust aerosol distribution

    NASA Astrophysics Data System (ADS)

    Schepanski, Kerstin; Klüser, Lars; Heinold, Bernd; Tegen, Ina

    2015-12-01

    Fields of dust aerosol optical depth (AOD) from numerical models and satellite observations are widely used data sets for evaluating the actual distribution of atmospheric dust aerosol. In this study we investigate the use of estimates of spatial and temporal correlation lengths (CLs) calculated from simulations using the regional model system COSMO-MUSCAT (COSMO: Consortium for Small-scale Modelling; MUSCAT: MUltiScale Chemistry Aerosol Transport Model) to characterize the spatial and temporal variability of atmospheric aerosol distribution, here mineral dust, and to provide an estimate on the temporal model output interval required in order to represent the local evolution of atmospheric dustiness. The CLs indicate the scales of variability for dust and thus provide an estimate for the stationarity of dust conditions in space and time. Additionally, CLs can be an estimate for the required resolution in time and space of observational systems to observe changes in atmospheric dust conditions that would be relevant for dust forecasts. Here, two years of dust simulations using COSMO-MUSCAT are analyzed. CLs for the individual years 2007 and 2008 are compared to the entire two-year period illustrating the impact of the length of time series on statistical analysis. The two years are chosen as they are contrasting with regard to mineral dust loads and thus provide additional information on the representativeness of the statistical analysis. Results from the COSMO-MUSCAT CL analysis are compared against CL estimates from satellite observations, here dust AOD inferred from IASI (Infrared Atmospheric Sounding Interferometer), which provides bi-daily information of atmospheric dust loading over desert land and ocean. Although CLs estimated from the satellite observations are at a generally lower level of values, the results demonstrate the applicability of daily observations for assessing the atmospheric dust distribution. Main outcomes of this study illustrate the

  11. [Sonographic leg length measurement].

    PubMed

    Holst, A; Thomas, W

    1989-03-01

    After brief presentation of the clinical and radiological methods to measure the leg length and the leg length difference the authors outline the new diagnostic method for measuring the leg length and the leg length difference by means of real time sonography. Postmortem tests and clinical examples show that ultrasound is ideal to determine exactly the length of femur and tibia. The joint gaps on the hip, knee and upper ankle joint can be demonstrated by means of a 5 MHz linear scanner. A 1 mm strong metal bar on the skin and under the scanner is placed at right angles to the longitudinal axis of the body so that the bar can be seen in the centre. A measuring device gives the distances of the joint gaps in cm so that the difference correspond to the real length of femur and tibia. This standardised measuring is done by a particularly developed bearing and measuring device. The results of the sonographical measurements on 20 corpses and checking after consecutive dissections showed in 75% of cases a 100% sonographic measuring accuracy of the total leg length. The separately considered results for femur (85%) and tibia (90) were even better. The maximum sonographic measuring fault was 1.0 cm for the femur (in one case) and 0.5 cm for the tibia, respectively. All sonographic measurements were performed with the Sonoline SL-1 of the Siemens Company (Erlangen, W-Germany). Thus, sonographical measuring of the leg length offers a reliable, non-invasive method that can be repeated as often as necessary and is simply executed.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2652268

  12. Softness Correlations Across Length Scales

    NASA Astrophysics Data System (ADS)

    Ivancic, Robert; Shavit, Amit; Rieser, Jennifer; Schoenholz, Samuel; Cubuk, Ekin; Durian, Douglas; Liu, Andrea; Riggleman, Robert

    In disordered systems, it is believed that mechanical failure begins with localized particle rearrangements. Recently, a machine learning method has been introduced to identify how likely a particle is to rearrange given its local structural environment, quantified by softness. We calculate the softness of particles in simulations of atomic Lennard-Jones mixtures, molecular Lennard-Jones oligomers, colloidal systems and granular systems. In each case, we find that the length scale characterizing spatial correlations of softness is approximately a particle diameter. These results provide a rationale for why localized rearrangements--whose size is presumably set by the scale of softness correlations--might occur in disordered systems across many length scales. Supported by DOE DE-FG02-05ER46199.

  13. Measuring Crack Length in Coarse Grain Ceramics

    NASA Technical Reports Server (NTRS)

    Salem, Jonathan A.; Ghosn, Louis J.

    2010-01-01

    Due to a coarse grain structure, crack lengths in precracked spinel specimens could not be measured optically, so the crack lengths and fracture toughness were estimated by strain gage measurements. An expression was developed via finite element analysis to correlate the measured strain with crack length in four-point flexure. The fracture toughness estimated by the strain gaged samples and another standardized method were in agreement.

  14. Correlation between the forearm plus little finger length and the femoral length.

    PubMed

    Naik, Monappa A; Sujir, Premjit; Tripathy, Sujit Kumar; Goyal, Tarun; Rao, Sharath K

    2013-08-01

    PURPOSE. To assess the correlation between the forearm plus little finger length and the femoral length in 100 volunteers. METHODS. The forearm plus little finger length and the ipsilateral femoral length of 68 male and 32 female volunteers aged 19 to 55 (mean, 35.8) years were measured using a measuring tape. The forearm plus litter finger length was measured from the tip of the olecranon to the tip of the little finger, whereas the femoral length was measured from the tip of the greater trochanter to the level of proximal pole of the patella over the outer aspect of thigh. Two observers made the measurements on 2 separate occasions. Intra- and inter-observer variations were calculated. A value of 0.75 or greater indicated excellent agreement. RESULTS. The mean forearm plus little finger length and femoral length were 39.87 (SD, 2.73) and 39.85 (SD, 2.44) cm, respectively. The mean difference between these 2 measurements was 0.028 (95% CI, -0.109 to 0.165) cm. The correlation between these 2 measurements was 0.861 (p<0.001). Patient age, sex, and body mass index did not affect this correlation. The intra- and inter-observer reliability was excellent. CONCLUSION. The forearm plus little finger length correlated with the femoral length. This method is simple, radiation-free, and can be applied in day-today practice. PMID:24014776

  15. Correlation length for interplanetary magnetic field fluctuations.

    NASA Technical Reports Server (NTRS)

    Fisk, L. A.; Sari, J. W.

    1973-01-01

    It is argued that it is necessary to consider two correlation lengths for interplanetary magnetic field fluctuations. For particles with gyroradii large enough to encounter and be scattered by large-scale tangential discontinuities in the field (particles with energies of above several GeV/nucleon) the appropriate correlation length is simply the mean spatial separation between the discontinuities. Particles with gyroradii much less than this mean separation appear to be unaffected by the discontinuities and respond only to smaller-scale field fluctuations. With this system of two correlation lengths the cosmic ray diffusion tensor may be altered from what was predicted by, for example, Jokipii and Coleman, and the objections raised recently by Klimas and Sandri to the diffusion analysis of Jokipii may apply only at relatively low energies (about 50 MeV/nucleon).

  16. Overview of bunch length measurements.

    SciTech Connect

    Lumpkin, A. H.

    1999-02-19

    An overview of particle and photon beam bunch length measurements is presented in the context of free-electron laser (FEL) challenges. Particle-beam peak current is a critical factor in obtaining adequate FEL gain for both oscillators and self-amplified spontaneous emission (SASE) devices. Since measurement of charge is a standard measurement, the bunch length becomes the key issue for ultrashort bunches. Both time-domain and frequency-domain techniques are presented in the context of using electromagnetic radiation over eight orders of magnitude in wavelength. In addition, the measurement of microbunching in a micropulse is addressed.

  17. Quark ensembles with the infinite correlation length

    SciTech Connect

    Zinov’ev, G. M.; Molodtsov, S. V.

    2015-01-15

    A number of exactly integrable (quark) models of quantum field theory with the infinite correlation length have been considered. It has been shown that the standard vacuum quark ensemble—Dirac sea (in the case of the space-time dimension higher than three)—is unstable because of the strong degeneracy of a state, which is due to the character of the energy distribution. When the momentum cutoff parameter tends to infinity, the distribution becomes infinitely narrow, leading to large (unlimited) fluctuations. Various vacuum ensembles—Dirac sea, neutral ensemble, color superconductor, and BCS state—have been compared. In the case of the color interaction between quarks, the BCS state has been certainly chosen as the ground state of the quark ensemble.

  18. Precise Measurement of Effective Focal Length

    NASA Technical Reports Server (NTRS)

    Wise, T. D.; Young, J. B.

    1983-01-01

    Computerized instrument measures effective focal lengths to 0.01 percent accuracy. Laser interferometers measure mirror angle and stage coordinate y in instrument for accurate measurment of focal properties of optical systems. Operates under computer control to measure effective focal length, focal surface shape, modulation transfer function, and astigmatism.

  19. Clinical evaluation of five electronic root canal length measuring instruments.

    PubMed

    Fouad, A F; Krell, K V; McKendry, D J; Koorbusch, G F; Olson, R A

    1990-09-01

    A previous in vitro study has shown high accuracy, but no clinically significant differences in a group of five electronic root canal length measuring instruments. The purpose of this study was to evaluate and compare the performance of the same group of instruments under clinical conditions and to correlate their accuracy to radiographic estimates of canal length. Five electronic root canal length measuring instruments were used to measure the working length to the "apex" in 20 single-rooted teeth scheduled for extraction. After extraction, the actual canal length was measured visually to a point just within the apical foramen. This length was compared with instrument length as determined electronically. The accuracy of the instruments in determining canal measurement within +/- 0.5 mm from the apical foramen varied from 55 to 75%. The differences between the instruments were not statistically significant. On average, all of the instruments except for the Endocater gave canal length measurements that were beyond the apical foramen. The variability of the measurements, which was comparable to that of estimates of canal length from preoperative radiographs, indicated that radiographic verification of the working length is still desirable. PMID:2098464

  20. Acyl Chain Length of Phosphatidylserine Is Correlated with Plant Lifespan

    PubMed Central

    Tian, Xuejun; Li, Weiqi

    2014-01-01

    Plant lifespan is affected by factors with genetic and environmental bases. The laws governing these two factors and how they affect plant lifespan are unclear. Here we show that the acyl chain length (ACL) of phosphatidylserine (PS) is correlated with plant lifespan. Among the detected eight head-group classes of membrane lipids with lipidomics based on triple quadrupole tandem mass spectrometry, the ACL of PS showed high diversity, in contrast to the ACLs of the other seven classes, which were highly conserved over all stages of development in all plant species and organs and under all conditions that we studied. Further investigation found that acyl chains of PS lengthened during development, senescence, and under environmental stresses and that increasing length was accelerated by promoted- senescence. The acyl chains of PS were limited to a certain carbon number and ceased to increase in length when plants were close to death. These findings suggest that the ACL of PS can count plant lifespan and could be a molecular scale ruler for measuring plant development and senescence. PMID:25058060

  1. Drift wave transport scalings introduced by varying correlation length

    SciTech Connect

    Weiland, J.; Holod, I.

    2005-01-01

    Scalings of the correlation length of drift wave turbulence with magnetic current q, shear, elongation, and temperature ratio have been introduced into a drift wave transport model. The correlation length is calculated from linear scaling of the fastest growing mode. Such a procedure is supported by previous turbulence simulations with absorbing boundaries for short and long wavelengths. The resulting q and s scalings are now in better agreement with experimental scalings. In particular, the simulation results for transport barrier shots improve.

  2. Carbon Nanotubes: Measuring Dispersion and Length

    SciTech Connect

    Fagan, Jeffrey A.; Bauer, Barry J.; Hobbie, Erik K.; Becker, Matthew L.; Hight-Walker, Angela; Simpson, Jeffrey R.; Chun, Jaehun; Obrzut, Jan; Bajpai, Vardhan; Phelan, Fred R.; Simien, Daneesh; Yeon Huh, Ji; Migler, Kalman B.

    2011-03-01

    Advanced technological uses of single-wall carbon nanotubes (SWCNTs) rely on the production of single length and chirality populations that are currently only available through liquid phase post processing. The foundation of all of these processing steps is the attainment of individualized nanotube dispersion in solution; an understanding of the collodial properties of the dispersed SWCNTs can then be used to designed appropriate conditions for separations. In many instances nanotube size, particularly length, is especially active in determining the achievable properties from a given population, and thus there is a critical need for measurement technologies for both length distribution and effective separation techniques. In this Progress Report, we document the current state of the art for measuring dispersion and length populations, including separations, and use examples to demonstrate the desirability of addressing these parameters.

  3. Bunch length measurements using synchrotron ligth monitor

    SciTech Connect

    Ahmad, Mahmoud; Tiefenback, Michael G.

    2015-09-01

    The bunch length is measured at CEBAF using an invasive technique. The technique depends on applying an energy chirp for the electron bunch and imaging it through a dispersive region. The measurements are taken through Arc1 and Arc2 at CEBAF. The fundamental equations, procedure and the latest results are given.

  4. Telomere length correlates with life span of dog breeds.

    PubMed

    Fick, Laura J; Fick, Gordon H; Li, Zichen; Cao, Eric; Bao, Bo; Heffelfinger, Doug; Parker, Heidi G; Ostrander, Elaine A; Riabowol, Karl

    2012-12-27

    Telomeric DNA repeats are lost as normal somatic cells replicate. When telomeres reach a critically short length, a DNA damage signal is initiated, inducing cell senescence. Some studies have indicated that telomere length correlates with mortality, suggesting that telomere length contributes to human life span; however, other studies report no correlation, and thus the issue remains controversial. Domestic dogs show parallels in telomere biology to humans, with similar telomere length, telomere attrition, and absence of somatic cell telomerase activity. Using this model, we find that peripheral blood mononuclear cell (PBMC) telomere length is a strong predictor of average life span among 15 different breeds (p < 0.0001), consistent with telomeres playing a role in life span determination. Dogs lose telomeric DNA ~10-fold faster than humans, which is similar to the ratio of average life spans between these species. Breeds with shorter mean telomere lengths show an increased probability of death from cardiovascular disease, which was previously correlated with short telomere length in humans. PMID:23260664

  5. Distance and Cable Length Measurement System

    PubMed Central

    Hernández, Sergio Elias; Acosta, Leopoldo; Toledo, Jonay

    2009-01-01

    A simple, economic and successful design for distance and cable length detection is presented. The measurement system is based on the continuous repetition of a pulse that endlessly travels along the distance to be detected. There is a pulse repeater at both ends of the distance or cable to be measured. The endless repetition of the pulse generates a frequency that varies almost inversely with the distance to be measured. The resolution and distance or cable length range could be adjusted by varying the repetition time delay introduced at both ends and the measurement time. With this design a distance can be measured with centimeter resolution using electronic system with microsecond resolution, simplifying classical time of flight designs which require electronics with picosecond resolution. This design was also applied to position measurement. PMID:22303169

  6. Length and Dimensional Measurements at NIST

    PubMed Central

    Swyt, Dennis A.

    2001-01-01

    This paper discusses the past, present, and future of length and dimensional measurements at NIST. It covers the evolution of the SI unit of length through its three definitions and the evolution of NBS-NIST dimensional measurement from early linescales and gage blocks to a future of atom-based dimensional standards. Current capabilities include dimensional measurements over a range of fourteen orders of magnitude. Uncertainties of measurements on different types of material artifacts range down to 7×10−8 m at 1 m and 8 picometers (pm) at 300 pm. Current work deals with a broad range of areas of dimensional metrology. These include: large-scale coordinate systems; complex form; microform; surface finish; two-dimensional grids; optical, scanning-electron, atomic-force, and scanning-tunneling microscopies; atomic-scale displacement; and atom-based artifacts.

  7. How Cells Measure Length on Subcellular Scales.

    PubMed

    Marshall, Wallace F

    2015-12-01

    Cells are not just amorphous bags of enzymes, but precise and complex machines. With any machine, it is important that the parts be of the right size, yet our understanding of the mechanisms that control size of cellular structures remains at a rudimentary level in most cases. One problem with studying size control is that many cellular organelles have complex 3D structures that make their size hard to measure. Here we focus on linear structures within cells, for which the problem of size control reduces to the problem of length control. We compare and contrast potential mechanisms for length control to understand how cells solve simple geometry problems. PMID:26437596

  8. Determining Correlation and Coherence Lengths in Turbulent Boundary Layer Flight Data

    NASA Technical Reports Server (NTRS)

    Palumbo, Dan

    2012-01-01

    Wall pressure data acquired during flight tests at several flight conditions are analysed and the correlation and coherence lengths of the data reported. It is found that the correlation and coherence lengths are influenced by the origin of the structure producing the pressure and the frequency bandwidth over which the analyses are performed. It is shown how the frequency bandwidth biases the correlation length and how the convection of the pressure field might reduce the coherence measured between sensors. A convected form of the cross correlation and cross spectrum is introduced to compensate for the effects of convection. Coherence lengths measured in the streamwise direction appear much longer than expected. Coherent structures detected using the convected cross correlation do not exhibit an exponential coherent power decay.

  9. The correlation length for interplanetary magnetic field fluctuations

    NASA Technical Reports Server (NTRS)

    Fisk, L. A.; Sari, J. W.

    1972-01-01

    It is argued that it is appropriate to consider two correlation lengths for interplanetary magnetic field fluctuations. For particles with gyro-radii large enough to encounter and be scattered by large-scale tangential discontinuities in the field (particles with energies greater than or approximately equal to several GeV/nucleon) the appropriate correlation length is simply the mean spatial separation between the discontinuities, L approximately 2 x 10 to the 11th power. Particles with gyro-radii much less than this mean separation (energies less than or approximately equal to 100 MeV/nucleon) appear to be unaffected by the discontinuities and respond only to smaller-scale field fluctuations. For these particles the correlation length is shown to be L approximately 10 to the 10th power cm. With this system of two correlation lengths the cosmic-ray diffusion tensor may be altered from what was predicted by, for example, Jokipii and Coleman, and the objections raised recently by Klimas and Sandri to the diffusion analysis of Jokipii may apply only at relatively low energies (approximately 50 MeV/nucleon).

  10. Measuring scattering lengths of gaseous samples

    NASA Astrophysics Data System (ADS)

    Huber, M. G.; Black, T. C.; Haun, R.; Pushin, D. A.; Shahi, C. B.; Weitfeldt, F. E.

    2016-03-01

    Neutron interferometry represents one of the most precise techniques for measuring the coherent scattering lengths (bc) of particular nuclear isotopes. Currently bc for helium-4 is known only to 1% relative uncertainty; a factor of ten higher than precision measurements of other light isotopes. Scattering lengths are measured using a neutron interferometer and by comparing the phase shift a neutron acquires as it passes through a gaseous sample relative to that of a neutron passing through vacuum. The density of the gas is determined by continuous monitoring of the sample's temperature and pressure. Challenges for these types of experiments include achieving the necessary long-term phase stability and accurate determination of the phase shift caused by the aluminum cell used to hold the gas; a phase shift many times greater than that of the sample. The present status on the effort to measure the n-4He scattering length at the NIST center for Neutron Research will be given. Financial support provided by the NSERC `Create' and `Discovery' programs, CERC, NIST and NSF Grant PHY-1205342.

  11. Ultrasound velocities for axial eye length measurement.

    PubMed

    Hoffer, K J

    1994-09-01

    Since 1974, I have used individual sound velocities for each eye condition encountered for axial length measurement. The calculation results in 1,555 M/sec for the average phakic eye. A slower speed of 1,549 M/sec was found for an extremely long (30 mm) eye and a higher speed of 1,561 M/sec was noted for an extremely short (20 mm) eye. This inversely proportional velocity change can best be adjusted for by measuring the phakic eye at 1,532 M/sec and correcting the result by dividing the square of the measured axial length (AL1,532)2 by the difference of the measured axial length (AL1,532) minus 0.35 mm. A velocity of 1,534 M/sec was found for all aphakic eyes regardless of their length, and correction is clinically significant. The velocity of an eye containing a poly(methyl methacrylate) intraocular lens is not different from an average phakic eye but it does magnify the effect of axial length change. I recommend measuring the pseudophakic eye at 1,532 M/sec and adding to the result (AL1,532), + 0.04 + 44% of the IOL thickness. The speed for an eye with a silicone IOL was found to be 1,476 M/sec (or AL1,532 + 0.04 - 56% of IOL thickness) and for glass, 1,549 M/sec (or AL1,532 + 0.04 + 75% of IOL thickness). A speed of 1,139 M/sec was found for a phakic eye with silicone oil filling most of the vitreous cavity and 1,052 M/sec for an aphakic eye filled with oil. For varying volumes of oil, each eye should be calculated individually. The speed was 534 M/sec for phakic eyes filled with gas. Eyes containing a silicone IOL or oil or gas will create clinically significant errors (3 to 10 diopters) if the sound velocity is not corrected. PMID:7996413

  12. Slip length measurement of gas flow.

    PubMed

    Maali, Abdelhamid; Colin, Stéphane; Bhushan, Bharat

    2016-09-16

    In this paper, we present a review of the most important techniques used to measure the slip length of gas flow on isothermal surfaces. First, we present the famous Millikan experiment and then the rotating cylinder and spinning rotor gauge methods. Then, we describe the gas flow rate experiment, which is the most widely used technique to probe a confined gas and measure the slip. Finally, we present a promising technique using an atomic force microscope introduced recently to study the behavior of nanoscale confined gas. PMID:27505860

  13. Slip length measurement of gas flow

    NASA Astrophysics Data System (ADS)

    Maali, Abdelhamid; Colin, Stéphane; Bhushan, Bharat

    2016-09-01

    In this paper, we present a review of the most important techniques used to measure the slip length of gas flow on isothermal surfaces. First, we present the famous Millikan experiment and then the rotating cylinder and spinning rotor gauge methods. Then, we describe the gas flow rate experiment, which is the most widely used technique to probe a confined gas and measure the slip. Finally, we present a promising technique using an atomic force microscope introduced recently to study the behavior of nanoscale confined gas.

  14. Torque correlation length and stochastic twist dynamics of DNA.

    PubMed

    Banigan, Edward J; Marko, John F

    2014-06-01

    We introduce a short correlation length for torque in twisting-stiff biomolecules, which is necessary for the physical property that torque fluctuations be finite in amplitude. We develop a nonequilibrium theory of dynamics of DNA twisting which predicts two crossover time scales for temporal torque correlations in single-molecule experiments. Bending fluctuations can be included, and at linear order we find that they do not affect the twist dynamics. However, twist fluctuations affect bending, and we predict the spatial inhomogeneity of twist, torque, and buckling arising in nonequilibrium "rotor-bead" experiments. PMID:25019813

  15. Correlative Measurements Program

    NASA Technical Reports Server (NTRS)

    Parsons, C. L.

    1988-01-01

    The GSFC Correlative Measurements Program at the Wallops Flight Facility was represented on the Satellite/Satellite Intercomparisons Working Group. The Correlative Measurements Program uses the Rocket Ozonesonde (ROCOZ-A) and the Electrochemical Concentration Cell (ECC) balloon borne ozonesonde to measure the vertical profile of ozone amount in the atmosphere. The balloon work is described in a separate report. The ROCOZ-A instrument was used for many years to provide in situ truth data for various satellite ozone measuring systems, such as SBUV on Nimbus-7, SAGE-II, SBUV-II on the NOAA series of polar orbiting satellites, SME, LIMS, etc. The particular data sets of interest to the Ozone Trends Panel Working Group were collected at Natal, Brazil. The major results produced for and used by the Ozone Trends Panel are shown. The ROCOZ-A average ozone density profile is plotted versus altitude on the left. ECC ozonesondes were used for the portion of the profile below 20 km, the lower limit for ROCOZ-A. The difference between SAGE-II and ROCOZ-A average density profiles is shown.

  16. Cross correlation and length scales in turbulent flows near surfaces

    NASA Technical Reports Server (NTRS)

    Hunt, J. C. R.; Moin, P.; Lee, M.; Moser, R. D.; Spalart, P.; Mansour, N. N.; Kaimal, J. C.; Gaynor, E.

    1989-01-01

    Two kinds of length scales are used in turbulent flows; 'functional length scales' such as mixing length, dissipation length L(sub epsilon), etc., and 'flow-field length scales' derived from cross correlations of velocity, pressure, etc. in the flow. Some connection between these scales are derived here. We first consider the cross correlation R(sub vv)(y,y(sub 1)) of the normal components u at two heights y, y(sub 1) above a rigid surface, normalized by the velocity y(sub 1) (greater than y). For shear-free boundary layers it is found theoretically, and in field and numerical experiments that R(sub vv) approximately equals y/y(sub 1). For shear layers it is also found that R(sub vv) approximately equals f(y/y(sub 1)) less than or equal to y,y(sub 1). This function f differs slightly between low Reynolds number numerical simulations and field experiments. The lateral structure defined by R(sub vv)(y,r(sub 3); y(sub 1),0) is also self similar and shows that the eddies centered at about y(sub 1) appear to have constant lateral width a(sub 3) above and below y(sub 1), where a(sub 3, sup +) approximately equals 7+1/(1.4dU(sup +)/dy(sup +)), when normalized on u(sub *) and v, where U is the mean velocity. Results for L(sub epsilon, sup -1) from direct numerical simulation are found to compare well with the formula L(sub epsilon, sup -1) = A(sub B)/y + A(sub S)dU/dy/v, for unidirectional and reversing turbulent boundary layers and channel flow, except near where dU/dy approximately equals 0. The conclusion is that the large-scale eddy structure and length scales in these flows are determined by a combination of shear and blocking, and that the vertical component of turbulence has a self-similar structure in both kinds of boundary layer.

  17. Standardisation of crown-rump length measurement.

    PubMed

    Ioannou, C; Sarris, I; Hoch, L; Salomon, L J; Papageorghiou, A T

    2013-09-01

    Correct estimation of gestational age is essential for any study of ultrasound biometry and for everyday clinical practice. However, inconsistency in pregnancy dating may occur through differences in measurement methods or errors during measurement. In the INTERGROWTH-21(st) Project, pregnancies are dated by the last menstrual period, provided that it is certain and associated with a regular menstrual cycle, and the gestational age by dates concurs with a first-trimester ultrasound crown-rump length (CRL) estimation. Hence, there was a need to standardise CRL measurement methodology across the study sites in this international, multicentre project to avoid systematic differences in dating. To achieve uniformity we undertook the following steps: the ultrasound technique was standardised by disseminating an illustrated, operating manual describing CRL plane landmarks and calliper application, and posters describing the correct acquisition technique were disseminated for quick reference. To ensure that all ultrasonographers understood the methodology, they forwarded a log-book to the INTERGROWTH-21(st) Ultrasound Coordinating Unit, containing the answers to a written test on the manual material and five images of a correctly acquired CRL. Interpretation of CRL was also standardised by ensuring that the same CRL regression formula was used across all study sites. These methods should minimise potential systematic errors in dating associated with pooling data from different health institutions, and represent a model for standardising CRL measurement in future studies. PMID:23678951

  18. Local-hybrid functional based on the correlation length

    SciTech Connect

    Johnson, Erin R.

    2014-09-28

    Local-hybrid functionals involve position-dependent mixing of Hartree-Fock and density-functional exchange, which should allow improved performance relative to conventional hybrids by reducing the inherent delocalization error and improving the long-range behaviour. Herein, the same-spin correlation length, obtained from the Fermi-hole radius, is used as the mixing parameter. The performance of the resulting local-hybrid functional is assessed for standard thermochemical and kinetics benchmarks. The local hybrid is shown to perform significantly better than the corresponding global hybrid in almost all cases.

  19. Intraoperative small bowel length measurements and analysis of demographic predictors of increased length.

    PubMed

    Teitelbaum, Ezra N; Vaziri, Khashayar; Zettervall, Sara; Amdur, Richard L; Orkin, Bruce A

    2013-10-01

    Few studies have measured small bowel length (SBL) in live humans and many textbooks base their "normal" SBL values on cadaver data. Here, we present a series of intraoperative SBL measurements and analyze predictors of increased length. SBL from ligament of Treitz to ileocecal valve was measured in patients undergoing laparotomy for colorectal resection. Patients with Crohn's disease and those who had undergone prior bowel resections were excluded. In the 240 patients studied, mean SBL was 506 ± 105 (285-845) cm. Height was positively associated with increased SBL (P < 0.001) and men had longer SBL than women (533 vs. 482 cm, P < 0.001). A multivariate linear regression model using patient sex, age, height and weight was significant (P = 0.001) and the predictors explained 8% of the variance in SBL. In this model, only height was independently predictive of increased SBL (P = 0.03). Correlation results differed between sexes. In men, height correlated with increased SBL (r = 0.20; P = 0.03), whereas in women it did not. In men, age had a positive correlation with SBL at a trend level (r = 0.17; P = 0.08), whereas in women age had a negative correlation with SBL (r = -0.18; P = 0.04). The mean SBL was 506 cm in live patients, as compared with the 600-700 cm range derived from prior cadaver studies. Male sex and height had positive correlations with SBL. SBL may decrease with age in women but not in men. PMID:23519889

  20. Relating Vegetation Aerodynamic Roughness Length to Interferometric SAR Measurements

    NASA Technical Reports Server (NTRS)

    Saatchi, Sassan; Rodriquez, Ernesto

    1998-01-01

    In this paper, we investigate the feasibility of estimating aerodynamic roughness parameter from interferometric SAR (INSAR) measurements. The relation between the interferometric correlation and the rms height of the surface is presented analytically. Model simulations performed over realistic canopy parameters obtained from field measurements in boreal forest environment demonstrate the capability of the INSAR measurements for estimating and mapping surface roughness lengths over forests and/or other vegetation types. The procedure for estimating this parameter over boreal forests using the INSAR data is discussed and the possibility of extending the methodology over tropical forests is examined.

  1. Mask roughness induced LER: geometric model at long correlation lengths

    SciTech Connect

    McClinton, Brittany M.; Naulleau, Patrick P.

    2011-02-11

    Collective understanding of how both the resist and line-edge roughness (LER) on the mask affect the final printed LER has made significant advances. What is poorly understood, however, is the extent to which mask surface roughness couples to image plane LER as a function of illumination conditions, NA, and defocus. Recently, progress has been made in formulating a simplified solution for mask roughness induced LER. Here, we investigate the LER behavior at long correlation lengths of surface roughness on the mask. We find that for correlation lengths greater than 3/NA in wafer dimensions and CDs greater than approximately 0.75/NA, the previously described simplified model, which remains based on physical optics, converges to a 'geometric regime' which is based on ray optics and is independent of partial coherence. In this 'geometric regime', the LER is proportional to the mask slope error as it propagates through focus, and provides a faster alternative to calculating LER in contrast to either full 2D aerial image simulation modeling or the newly proposed physical optics model. Data is presented for both an NA = 0.32 and an NA = 0.5 imaging system for CDs of 22-nm and 50-nm horizontal-line-dense structures.

  2. Automatic detection and measurement of femur length from fetal ultrasonography

    NASA Astrophysics Data System (ADS)

    Mukherjee, Prateep; Swamy, Gokul; Gupta, Madhumita; Patil, Uday; Krishnan, Kajoli Banerjee

    2010-03-01

    Femur bone length is used in the assessment of fetal development and in the prediction of gestational age (GA). In this paper, we present a completely automated two-step method for identifying fetal femur and measuring its length from 2D ultrasound images. The detection algorithm uses a normalized score premised on the distribution of anatomical shape, size and presentation of the femur bone in clinically acceptable scans. The measurement process utilizes a polynomial curve fitting technique to determine the end-points of the bone from a 1D profile that is most distal from the transducer surface. The method has been tested with manual measurements made on 90 third trimester femur images by two radiologists. The measurements made by the experts are strongly correlated (Pearson's coefficient = 0.95). Likewise, the algorithm estimate is strongly correlated with expert measurements (Pearson's coefficient = 0.92 and 0.94). Based on GA estimates and their bounds specified in Standard Obstetric Tables, the GA predictions from automated measurements are found to be within +/-2SD of GA estimates from both manual measurements in 89/90 cases and within +/-3SD in all 90 cases. The method presented in this paper can be adapted to perform automatic measurement of other fetal limbs.

  3. Near-infrared digital photography to estimate snow correlation length for microwave emission modeling.

    PubMed

    Toure, Ally Mounirou; Goïta, Kalifa; Royer, Alain; Mätzler, Christian; Schneebeli, Martin

    2008-12-20

    The study is based on experimental work conducted in alpine snow. We made microwave radiometric and near-infrared reflectance measurements of snow slabs under different experimental conditions. We used an empirical relation to link near-infrared reflectance of snow to the specific surface area (SSA), and converted the SSA into the correlation length. From the measurements of snow radiances at 21 and 35 GHz, we derived the microwave scattering coefficient by inverting two coupled radiative transfer models (the sandwich and six-flux model). The correlation lengths found are in the same range as those determined in the literature using cold laboratory work. The technique shows great potential in the determination of the snow correlation length under field conditions. PMID:19104524

  4. Reversal modes in FeCoNi nanowire arrays: Correlation between magnetostatic interactions and nanowires length

    NASA Astrophysics Data System (ADS)

    Samanifar, S.; Almasi Kashi, M.; Ramazani, A.; Alikhani, M.

    2015-03-01

    FeCoNi nanowire arrays (175 nm in diameter and lengths ranging from 5 to 40 μm) were fabricated into nanopores of hard-anodized aluminum oxide templates using pulsed ac electrodeposition technique. Increasing the length had no considerable effect on the composition and crystalline characteristics of Fe47Co38Ni15 nanowires (NWs). By eliminating the dendrites formed at the bottom of the pores, we report a careful investigation on the effect of magnetostatic interactions on magnetic properties and the effect of nanowire length on reversal modes. Hysteresis loop measurements indicated that increasing the length decreases coercivity and squareness values. On the other hand, first-order reversal curve measurements show a linear correlation between the magnetostatic interactions and length of NWs. Comparing reversal modes of the NWs both experimentally and theoretically using angular dependence of coercivity, we find that when L≤22 μm, a vortex domain wall mode is only occurred. When L>22 μm, a non-monotonic behavior indicates a transition from the vortex to transverse domain wall propagation. As a result, a critical length was found above which the transition between the reversal modes is occurred due the enhanced interactions. The transition angle also shifts toward a lower angle as the length increases. Moreover, with increasing length from 22 to 31 μm, the single domain structure of NWs changes to a pseudo single domain state. A multidomain-like behavior is also found for the longest NWs length.

  5. Evaluation of the normal fetal kidney length and its correlation with gestational age.

    PubMed

    Seilanian Toosi, Farrokh; Rezaie-Delui, Hossein

    2013-01-01

    A true estimation of gestational age (GA) plays an important role in quality maternity care and scheduling the labor date. This study aimed to evaluate the normal fetal kidney length (KL) and its correlation with GA. A cross-sectional study on 92 pregnant women between 8th and 10th week of gestation with normal singleton pregnancy underwent standard ultrasound fetal biometry and kidney length measurement. univariate and multivariate linear regression analysis was used to create a predictive equation to estimate GA on the KL and fetobiometry parameters. A significant correlation was found between GA and KL (r=0.83, P<0.002). The best GA predictor was obtained by combining head circumference, fetal biparietal diameter, femur length and KL with a standard error (SE) about 14.2 days. Our findings showed that KL measurements combination with other fetal biometric parameters could predict age of pregnancy with a better precision. PMID:23737313

  6. 50 CFR Appendix C to Part 622 - Fish Length Measurements

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 12 2012-10-01 2012-10-01 false Fish Length Measurements C Appendix C to... Appendix C to Part 622—Fish Length Measurements ER03JY96.000 Figure 1 of Appendix C to Part 622—Carapace Length ER25JA99.001 Figure 2 of Appendix C to Part 622—Illustration of Length Measurements...

  7. Direct measure of quantum correlation

    SciTech Connect

    Yu, Chang-shui; Zhao, Haiqing

    2011-12-15

    The quantumness of the correlation known as quantum correlation is usually measured by quantum discord. So far various quantum discords can be roughly understood as indirect measure by some special discrepancy of two quantities. We present a direct measure of quantum correlation by revealing the difference between the structures of classically and quantum correlated states. Our measure explicitly includes the contributions of the inseparability and local nonorthogonality of the eigenvectors of a density matrix. Besides its relatively easy computability, our measure can provide a unified understanding of quantum correlation of all the present versions.

  8. Correlation of the hand length and stature in adult Musahar females of Nepal; an anthropometric study.

    PubMed

    Basnet, K S; Dhungel, S; Panta, P P

    2012-03-01

    Stature of a person is one of the most important and useful anthropometric parameter for establishing identification of unknown living or a dead person. A descriptive cross sectional study was done on 165 Nepalese adult Musahar females of Aurahi Village of Mahottari district, Nepal to predict the stature from their hand length. Measurement of stature and the length of both right and left hands taken with a standard standing height measuring instrument and a slide caliper respectively showed significant (p<0.001) positive correlation between the stature and hand lengths. The multiplication factor which was obtained by dividing the height of the subject by the respective hand lengths was found appropriate parameter to calculate the stature of a questioned person. The importance of the hand length alone will be of a great value for anthropologists and forensic experts. As an alternative method, the coefficient of regression and intercept which were obtained from the measured height and hand length were also proved to be equally valuable to estimate the height of a questioned person. PMID:23441496

  9. [Measuring leg length and leg length difference with the method of real time sonography].

    PubMed

    Holst, A; Thomas, W

    1988-06-01

    A brief presentation of the clinical and radiological methods to measure the leg length and the leg length difference is followed by an outline of the new diagnostic method for measuring the leg length and the leg length difference by means of real-time sonography. Tests conducted on corpses, as well as clinical examples, show that sonography is an ideal method for determining the exact lengths of the femur and tibia. The joint gaps on the hip joint, knee joint and upper ankle joint can be visualised by means of a 5 MHz linear scanner. A 1 mm strong metal bar on the skin and under the scanner are positioned at a right angle to the longitudinal axis of the body so that the bar can be seen in the centre of each joint gap by means of real-time sonography. A measuring device gives the distances of the joint gaps in cm so that the differences correspond to the real length of femur and tibia. This standardised measuring procedure is done by a specially developed bearing and measuring device. The results of the sonographical measurings on 20 corpses and checking after consecutive dissections showed in 75% of the cases a 100% sonographic measuring accuracy of the total leg length. The separately considered results for femur (85%) and tibia (90%) were even better. The maximum sonographic measuring fault was 1.0 cm for the femur (in one case) and 0.5 cm for the tibia, respectively. Thus, sonographic measuring of the leg length offers a reliable, non-invasive and easily performed new method that can be repeated any number of times. It is ideal for the development control of therapeutically influenced as well as spontaneous transformations of leg length differences. PMID:3071879

  10. Accurate Fiber Length Measurement Using Time-of-Flight Technique

    NASA Astrophysics Data System (ADS)

    Terra, Osama; Hussein, Hatem

    2016-06-01

    Fiber artifacts of very well-measured length are required for the calibration of optical time domain reflectometers (OTDR). In this paper accurate length measurement of different fiber lengths using the time-of-flight technique is performed. A setup is proposed to measure accurately lengths from 1 to 40 km at 1,550 and 1,310 nm using high-speed electro-optic modulator and photodetector. This setup offers traceability to the SI unit of time, the second (and hence to meter by definition), by locking the time interval counter to the Global Positioning System (GPS)-disciplined quartz oscillator. Additionally, the length of a recirculating loop artifact is measured and compared with the measurement made for the same fiber by the National Physical Laboratory of United Kingdom (NPL). Finally, a method is proposed to relatively correct the fiber refractive index to allow accurate fiber length measurement.

  11. Measurements of Newton's gravitational constant and the length of day

    NASA Astrophysics Data System (ADS)

    Anderson, J. D.; Schubert, G.; Trimble, V.; Feldman, M. R.

    2015-04-01

    About a dozen measurements of Newton's gravitational constant, G, since 1962 have yielded values that differ by far more than their reported random plus systematic errors. We find that these values for G are oscillatory in nature, with a period of P = 5.899 +/- 0.062 \\text{yr} , an amplitude of (1.619 +/- 0.103) × 10-14 \\text{m}3 \\text{kg}-1 \\text{s}-2 , and mean-value crossings in 1994 and 1997. However, we do not suggest that G is actually varying by this much, this quickly, but instead that something in the measurement process varies. Of other recently reported results, to the best of our knowledge, the only measurement with the same period and phase is the Length of Day (LOD —defined as a frequency measurement such that a positive increase in LOD values means slower Earth rotation rates and therefore longer days). The aforementioned period is also about half of a solar activity cycle, but the correlation is far less convincing. The 5.9 year periodic signal in LOD has previously been interpreted as due to fluid core motions and inner-core coupling. We report the G/LOD correlation, whose statistical significance is 0.99764 assuming no difference in phase, without claiming to have any satisfactory explanation for it. Least unlikely, perhaps, are currents in the Earth's fluid core that change both its moment of inertia (affecting LOD) and the circumstances in which the Earth-based experiments measure G. In this case, there might be correlations with terrestrial-magnetic-field measurements.

  12. 50 CFR Appendix C to Part 622 - Fish Length Measurements

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Fish Length Measurements C Appendix C to Part 622 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC... Appendix C to Part 622—Fish Length Measurements ER03JY96.000 Figure 1 of Appendix C to Part...

  13. 50 CFR Appendix C to Part 622 - Fish Length Measurements

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Fish Length Measurements C Appendix C to Part 622 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC... Appendix C to Part 622—Fish Length Measurements ER03JY96.000 Figure 1 of Appendix C to Part...

  14. 50 CFR Appendix C to Part 622 - Fish Length Measurements

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Fish Length Measurements C Appendix C to Part 622 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC..., App. C Appendix C to Part 622—Fish Length Measurements ER17AP13.000 ER17AP13.001...

  15. 50 CFR Appendix C to Part 622 - Fish Length Measurements

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false Fish Length Measurements C Appendix C to Part 622 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC..., App. C Appendix C to Part 622—Fish Length Measurements ER17AP13.000 ER17AP13.001...

  16. From Concrete to Abstract in the Measurement of Length

    NASA Astrophysics Data System (ADS)

    Stephanou, Andreas; Fisher, William P., Jr.

    2013-09-01

    The concatenation of units of length is widely viewed as the paradigmatic expression of fundamental measurement. Survey, assessment, and test scores in educational and psychological measurement are often interpreted in ways that assume a concatenation of units to have been established, even though these assumptions are rarely stated or tested. A concatenation model for measurement is shown to be equivalent to a Rasch model: any two units of measurement placed end to end must together be of the same length as either one of them added to itself. This additive principle and a concatenation model of measurement together serve as a heuristic guide for organizing two experimental approaches to calibrating instruments for measuring length. The capacity to reproduce the unit of measurement from theory with no need for repeated empirical calibration experiments, as in the geometrical bisection of the line and the resultant halving of the length measure, is highlighted as essential to demonstrating a thorough understanding of the construct.

  17. New transducers for measuring muscle length in unrestrained animals.

    PubMed

    Weytjens, J L; Viberg, D A; Caputi, A A; Kallesøe, K; Hoffer, J A

    1992-12-01

    Muscle length in unrestrained, chronically implanted animals is conventionally measured with gauges consisting of a compliant silicone rubber tube filled with either hypertonic saline or mercury, the measurement principle being a continuous change in the electrical resistance of the fluid column inside the tubing with stretch. These gauges have two major disadvantages: (1) changes in resistance that are not related to changes in length, such as those produced by changes in temperature or osmotic dilution of the hypertonic saline, cause the measurements to drift, and (2) there is no direct and accurate way to calibrate the measurements. In this communication two new types of muscle length gauge are described that eliminate both problems. Both types make use of the principle of sonomicrometry, i.e., the measurement of distances with pulsed ultrasound. Both types have been successfully used to measure the length of the medial gastrocnemius muscle in chronically implanted cats during treadmill locomotion. PMID:1294854

  18. Statistical length measurement method by direct imaging of carbon nanotubes.

    PubMed

    Bengio, E Amram; Tsentalovich, Dmitri E; Behabtu, Natnael; Kleinerman, Olga; Kesselman, Ellina; Schmidt, Judith; Talmon, Yeshayahu; Pasquali, Matteo

    2014-05-14

    The influence of carbon nanotube (CNT) length on their macroscopic properties requires an accurate methodology for CNT length measurement. So far, existing techniques are limited to short (less than a few micrometers) CNTs and sample preparation methods that bias the measured values. Here, we show that the average length of carbon nanotubes (CNTs) can be measured by cryogenic transmission electron microscopy (cryo-TEM) of CNTs in chlorosulfonic acid. The method consists of dissolving at low concentration CNTs in chlorosulfonic acid (a true solvent), imaging the individual CNTs by cryo-TEM, and processing and analyzing the images to determine CNT length. By measuring the total CNT contour length and number of CNT ends in each image, and by applying statistical analysis, we extend the method to cases where each CNT is long enough to span many cryo-TEM images, making the direct length measurement of an entire CNT impractical. Hence, this new technique can be used effectively to estimate samples in a wide range of CNT lengths, although we find that cryo-TEM imaging may bias the measurement towards longer CNTs, which are easier to detect. Our statistical method is also applied to AFM images of CNTs to show that, by using only a few AFM images, it yields estimates that are consistent with literature techniques, based on individually measuring a higher number of CNTs. PMID:24773046

  19. Correlation of Retinal Nerve Fiber Layer Thickness and Axial Length on Fourier Domain Optical Coherence Tomography

    PubMed Central

    Dhasmana, Renu; Nagpal, R.C.

    2016-01-01

    Introduction The assessment of the peripapillary Retinal Nerve Fiber Layer (RNFL) thickness has been an important tool for evaluating and diagnosing glaucoma and its progression. Literature suggests that myopic eyes are at an increased risk for developing glaucoma. This study gives an insight into the relationship of RNFL thickness to the axial length in normal population. Aim To correlate the RNFL thickness and the axial length in normal individuals with Fourier domain Optical Coherence Tomography (OCT). Materials and Methods In the current study, 298 eyes of 149 normal individuals (10 years or older) with or without refractive error were recruited. The RNFL thickness was measured using Optovue (RTVue) three-dimensional Fourier domain OCT. Results We observed an inverse relationship between average RNFL thickness and increasing axial length(p=0.003). Maximum RNFL thickness was seen in the Infero-Temporal (IT) quadrant and minimum in the Supero-Nasal (SN) quadrant. RNFL thickness did not show any tendency to decline with age using the Pearsons correlation (r=0.07). Females had an increased RNFL thickness in the Supero-Temporal (ST) and Infero-Nasal (IN) quadrant (p-value 0.046 and 0.02) in comparison to males. There was a statistically significant thinning in Ganglion Cell Complex (GCC) with increasing axial length (p-value 0.000) Conclusion The current study suggests that the average RNFL thickness does not decrease with age. The RNFL and GCC thickness shows an inverse correlation with axial length of the eyeball hence observations have to be carefully interpreted in myopic eyes. Clinicians need to keep the anatomical variations in RNFL for better patient management. PMID:27190850

  20. Mapping correlation lengths of lower crustal heterogeneities together with their maximum-likelihood uncertainties

    NASA Astrophysics Data System (ADS)

    Carpentier, S. F. A.; Roy-Chowdhury, K.; Hurich, C. A.

    2011-07-01

    A novel statistical technique has been applied to the AG-48 seismic line from the LITHOPROBE dataset, passing through the Abitibi-Grenville Province, Canada. The method maps lateral stochastic parameters, representing von Karman heterogeneity distributions in the crust, estimated from migrated deep reflection data. Together with these parameters, viz. lateral correlation length and power-law exponent, we also compute their associated maximum-likelihood uncertainties. Combining normalised measurements of lateral correlation and their uncertainties, objective profiles of crustal fabric can be made. These profiles indicate significant spatial variations in macro-scale petrofabric. Correlation length, which carries useful information about structural scale lengths of heterogeneous bodies, is an especially robust parameter with moderate associated uncertainties. Although the general outline of the profiles conforms to the earlier tectonic interpretations (based on line-drawings), new features are visible too. The macro-scale petrofabric is seen to vary significantly within the tectonic terrains identified earlier — in depth as well as laterally. A consequence of this additional delineation is that we can explain an existing part of the AG-48 line equally well in terms of collisional deformation and in terms of the effects of a major shear zone projected onto a parallel segment of the line.

  1. Correlation between length and tilt of lipid tails

    SciTech Connect

    Kopelevich, Dmitry I.; Nagle, John F.

    2015-10-21

    It is becoming recognized from simulations, and to a lesser extent from experiment, that the classical Helfrich-Canham membrane continuum mechanics model can be fruitfully enriched by the inclusion of molecular tilt, even in the fluid, chain disordered, biologically relevant phase of lipid bilayers. Enriched continuum theories then add a tilt modulus κ{sub θ} to accompany the well recognized bending modulus κ. Different enrichment theories largely agree for many properties, but it has been noticed that there is considerable disagreement in one prediction; one theory postulates that the average length of the hydrocarbon chain tails increases strongly with increasing tilt and another predicts no increase. Our analysis of an all-atom simulation favors the latter theory, but it also shows that the overall tail length decreases slightly with increasing tilt. We show that this deviation from continuum theory can be reconciled by consideration of the average shape of the tails, which is a descriptor not obviously includable in continuum theory.

  2. Far-from-equilibrium measurements of thermodynamic length

    SciTech Connect

    Feng, Edward H.; Crooks, Gavin E.

    2008-11-05

    Thermodynamic length is a path function that generalizes the notion of length to the surface of thermodynamic states. Here, we show how to measure thermodynamic length in far-from-equilibrium experiments using the work fluctuation relations. For these microscopic systems, it proves necessary to define the thermodynamic length in terms of the Fisher information. Consequently, the thermodynamic length can be directly related to the magnitude of fluctuations about equilibrium. The work fluctuation relations link the work and the free energy change during an external perturbation on a system. We use this result to determine equilibrium averages at intermediate points of the protocol in which the system is out-of-equilibrium. This allows us to extend Bennett's method to determine the potential of mean force, as well as the thermodynamic length, in single molecule experiments.

  3. Time correlators from deferred measurements

    NASA Astrophysics Data System (ADS)

    Oehri, D.; Lebedev, A. V.; Lesovik, G. B.; Blatter, G.

    2016-01-01

    Repeated measurements that typically occur in two-time or multitime correlators rely on von Neumann's projection postulate, telling how to restart the system after an intermediate measurement. We invoke the principle of deferred measurement to describe an alternative procedure in which coevolving quantum memories extract system information through entanglement, combined with a final readout of the memories described by Born's rule. Our approach to repeated quantum measurements respects the unitary evolution of quantum mechanics during intermediate times, unifies the treatment of strong and weak measurements, and reproduces the projected and (anti)symmetrized correlators in the two limits. As an illustration, we apply our formalism to the calculation of the electron charge correlator in a mesoscopic physics setting, where single electron pulses assume the role of flying memory qubits. We propose an experimental setup that reduces the measurement of the time correlator to the measurement of currents and noise, exploiting the (pulsed) injection of electrons to cope with the challenge of performing short-time measurements.

  4. Length measurements of mid-latitude scintillation irregularities

    SciTech Connect

    Macdougall, J.W. )

    1992-04-01

    The lengths of irregularities which produce 150-MHz amplitude scintillations have been measured at 43 deg N, 81 deg W (geographic) using arrays of receivers with large spacings. The average length (major axis radius) of the irregularities was 6.1 km. This is much shorter than expected and implies that the measurements are of 'young' irregularities, less than 1 minute old. These irregularities appear to be a large, 25-50-percent perturbation of the background density. 8 refs.

  5. Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients.

    PubMed

    Squassina, Alessio; Pisanu, Claudia; Congiu, Donatella; Caria, Paola; Frau, Daniela; Niola, Paola; Melis, Carla; Baggiani, Gioia; Lopez, Juan Pablo; Cruceanu, Cristiana; Turecki, Gustavo; Severino, Giovanni; Bocchetta, Alberto; Vanni, Roberta; Chillotti, Caterina; Del Zompo, Maria

    2016-07-01

    Bipolar disorder (BD) has been suggested to be associated with accelerated aging and premature cell senescence. While findings on shorter telomeres in BD are controversial, a recent study showed that long-term lithium treatment correlates with longer telomeres in BD. In our study, we sought to investigate the correlation between leukocyte telomere length (LTL) and long-term lithium treatment in a sample of 200 BD patients characterized for lithium response. We also compared data from two different methods commonly used to measure telomere length, quantitative PCR (qPCR) and quantitative fluorescence in situ hybridization (Q-FISH). We also measured, for the first time, the effect of lithium in vitro on the expression of the telomerase gene in human-derived neural progenitor cells (NPCs). Our findings showed that LTL correlated negatively with age (p=0.0002) and was independent of sex, diagnosis, age at onset, suicidal behavior, number of mood episodes, response to lithium and use of other psychotropic medications. After correcting for age, LTL was positively correlated with lithium treatment duration in patients treated for more than two years (n=150, R=0.17, p=0.037). There was a significant correlation between data measured with qPCR and Q-FISH (p=0.012, R=0.826). Lithium treatment increased telomerase expression in NPCs, though this effect was not statistically significant. Our data support previous findings showing that long-term lithium treatment associates with longer telomeres in BD, though this effect appeared to be independent from clinical response to the treatment. Moreover, we suggested for the first time that lithium increases the expression of telomerase gene in human neural progenitor cells. PMID:27084304

  6. Significant correlation of species longevity with DNA double strand break recognition but not with telomere length.

    PubMed

    Lorenzini, Antonello; Johnson, F Brad; Oliver, Anthony; Tresini, Maria; Smith, Jasmine S; Hdeib, Mona; Sell, Christian; Cristofalo, Vincent J; Stamato, Thomas D

    2009-01-01

    The identification of the cellular mechanisms responsible for the wide differences in species lifespan remains one of the major unsolved problems of the biology of aging. We measured the capacity of nuclear protein to recognize DNA double strand breaks (DSBs) and telomere length of skin fibroblasts derived from mammalian species that exhibit wide differences in longevity. Our results indicate DNA DSB recognition increases exponentially with longevity. Further, an analysis of the level of Ku80 protein in human, cow, and mouse suggests that Ku levels vary dramatically between species and these levels are strongly correlated with longevity. In contrast mean telomere length appears to decrease with increasing longevity of the species, although not significantly. These findings suggest that an enhanced ability to bind to DNA ends may be important for longevity. A number of possible roles for increased levels of Ku and DNA-PKcs are discussed. PMID:19896964

  7. Correlations between Muscle Activities and Strap Length and Types of School Bag during Walking.

    PubMed

    Yoon, Jung-Gyu

    2014-12-01

    [Purpose] The purpose of this study was to examine correlations between muscle activities and strap length and type of the school bag during walking. [Subjects and Methods] The subjects of this study were 20 healthy students. An 8-channel electromyograph (8-EMG) (Pocket EMG, BTS, Italy) was used to measure the muscle activities of the right upper trapezius, left upper trapezius, right erector spinae and left erector spinae during walking with the bag. The collected data were analyzed using Kendall's coefficient of concordance. [Results] The muscle activities of the right upper trapezius, left upper trapezius, right erector spinae and left erector spinae were significantly higher when walking with a shoulder bag than when walking with a backpack. No significant correlations were found between muscle activities and strap lengths of the bag. [Conclusion] While carrying a bag, the activities of the trunk muscles were influenced more by the type of the bag than by the strap length. These results indicate that a backpack is a better method of carrying a load than a shoulder bag. PMID:25540502

  8. Correlations between Muscle Activities and Strap Length and Types of School Bag during Walking

    PubMed Central

    Yoon, Jung-Gyu

    2014-01-01

    [Purpose] The purpose of this study was to examine correlations between muscle activities and strap length and type of the school bag during walking. [Subjects and Methods] The subjects of this study were 20 healthy students. An 8-channel electromyograph (8-EMG) (Pocket EMG, BTS, Italy) was used to measure the muscle activities of the right upper trapezius, left upper trapezius, right erector spinae and left erector spinae during walking with the bag. The collected data were analyzed using Kendall’s coefficient of concordance. [Results] The muscle activities of the right upper trapezius, left upper trapezius, right erector spinae and left erector spinae were significantly higher when walking with a shoulder bag than when walking with a backpack. No significant correlations were found between muscle activities and strap lengths of the bag. [Conclusion] While carrying a bag, the activities of the trunk muscles were influenced more by the type of the bag than by the strap length. These results indicate that a backpack is a better method of carrying a load than a shoulder bag. PMID:25540502

  9. Effective length measurements of prototype Main Injector Dipole endpacks

    SciTech Connect

    Glass, H.D.; Brown, B.C.; Harding, D.J.

    1993-03-03

    An endpack design has been developed for the Fermilab Main Injector Dipole. A major part of the design process was the testing of a series of prototype removable endpacks. The magnetic parameters that were tested included the effective length and the field shape variation. This report presents a description of the measurement techniques and the results for the effective length. The final endpack has an effective length at 1500 A (0.29T) of 2.6 {plus_minus} 0.3 mm greater than the steel length, and the change in effective length from 1500 A to maximum current of 9500 A (1.74T) is {minus}1.88 {plus_minus} 0.05 mm.

  10. Laser multi-reflection confocal long focal-length measurement

    NASA Astrophysics Data System (ADS)

    Li, Zhigang; Qiu, Lirong; Zhao, Weiqian; Xiao, Yang

    2016-06-01

    We propose a new laser multi-reflection confocal focal-length measurement (MCFM) method to meet the requirements of a high-precision measurement for a long focal-length more than 2 m. It places an optical flat and a reflector behind the test lens for reflecting the measuring beam repeatedly, and then, uses the property that the peak points of confocal response curves precisely corresponds to the convergence points of a multi-reflected measuring beam to exactly identify the positions of the convergence points. Subsequently, it obtains the position variation of the reflector with a different number of reflections by a distance measuring instrument, and thereby achieving the high precise long focal-length measurement. The theoretical analyses and preliminary experimental results indicate that MCFM has a relative standard uncertainty of 0.066% for a test lens with the focal-length of 9.76 m. MCFM can provide a novel approach for the high-precision focal-length measurement.

  11. Automated Defect and Correlation Length Analysis of Block Copolymer Thin Film Nanopatterns

    PubMed Central

    Murphy, Jeffrey N.; Harris, Kenneth D.; Buriak, Jillian M.

    2015-01-01

    Line patterns produced by lamellae- and cylinder-forming block copolymer (BCP) thin films are of widespread interest for their potential to enable nanoscale patterning over large areas. In order for such patterning methods to effectively integrate with current technologies, the resulting patterns need to have low defect densities, and be produced in a short timescale. To understand whether a given polymer or annealing method might potentially meet such challenges, it is necessary to examine the evolution of defects. Unfortunately, few tools are readily available to researchers, particularly those engaged in the synthesis and design of new polymeric systems with the potential for patterning, to measure defects in such line patterns. To this end, we present an image analysis tool, which we have developed and made available, to measure the characteristics of such patterns in an automated fashion. Additionally we apply the tool to six cylinder-forming polystyrene-block-poly(2-vinylpyridine) polymers thermally annealed to explore the relationship between the size of each polymer and measured characteristics including line period, line-width, defect density, line-edge roughness (LER), line-width roughness (LWR), and correlation length. Finally, we explore the line-edge roughness, line-width roughness, defect density, and correlation length as a function of the image area sampled to determine each in a more rigorous fashion. PMID:26207990

  12. Telomere Length: A Review of Methods for Measurement

    PubMed Central

    Montpetit, Alison J.; Alhareeri, Areej A.; Montpetit, Marty; Starkweather, Angela R.; Elmore, Lynne W.; Filler, Kristin; Mohanraj, Lathika; Burton, Candace W.; Menzies, Victoria S.; Lyon, Debra E.; Collins, Judith B.; Teefey, Joseph M.; Jackson-Cook, Colleen K.

    2014-01-01

    Background The exciting discovery that telomere shortening is associated with many health conditions, and that telomere lengths can be altered in response to social and environmental exposures, has underscored the need for methods to accurately and consistently quantify telomere length. Objectives The purpose of this paper is to provide a comprehensive summary that compares and contrasts the current technologies used to assess telomere length. Discussion Multiple methods have been developed for the study of telomeres. These techniques include quantification of telomere length by terminal restriction fragmentation—which was one of the earliest tools used for length assessment—making it the gold standard in telomere biology. Quantitative-PCR provides the advantage of being able to use smaller amounts of DNA, thereby making it amenable to epidemiology studies involving large numbers of people. An alternative method uses fluorescent probes to quantify not only mean telomere lengths, but also chromosome-specific telomere lengths; however, the downside of this approach is that it can only be used on mitotically active cells. Additional methods that permit assessment of the length of a subset of chromosome-specific telomeres, or the subset of telomeres that demonstrate shortening, are also reviewed. Conclusion Given the increased utility for telomere assessments as a biomarker in physiological, psychological and biobehavioral research, it is important that investigators become familiar with the methodological nuances of the various procedures used for measuring telomere length. This will ensure that they are empowered to select an optimal assessment approach to meet the needs of their study designs. Gaining a better understanding of the benefits and drawbacks of various measurement techniques is important not only in individual studies, but also to further establish the science of telomere associations with biobehavioral phenomena. PMID:24977726

  13. Measurement of Debye length in laser-produced plasma.

    NASA Technical Reports Server (NTRS)

    Ehler, W.

    1973-01-01

    The Debye length of an expanded plasma created by placing an evacuated chamber with an entrance slit in the path of a freely expanding laser produced plasma was measured, using the slab geometry. An independent measurement of electron density together with the observed value for the Debye length also provided a means for evaluating the plasma electron temperature. This temperature has applications in ascertaining plasma conductivity and magnetic field necessary for confinement of the laser produced plasma. Also, the temperature obtained would be useful in analyzing electron-ion recombination rates in the expanded plasma and the dynamics of the cooling process of the plasma expansion.

  14. Evaluation of correlation property of linear-frequency-modulated signals coded by maximum-length sequences

    NASA Astrophysics Data System (ADS)

    Yamanaka, Kota; Hirata, Shinnosuke; Hachiya, Hiroyuki

    2016-07-01

    Ultrasonic distance measurement for obstacles has been recently applied in automobiles. The pulse–echo method based on the transmission of an ultrasonic pulse and time-of-flight (TOF) determination of the reflected echo is one of the typical methods of ultrasonic distance measurement. Improvement of the signal-to-noise ratio (SNR) of the echo and the avoidance of crosstalk between ultrasonic sensors in the pulse–echo method are required in automotive measurement. The SNR of the reflected echo and the resolution of the TOF are improved by the employment of pulse compression using a maximum-length sequence (M-sequence), which is one of the binary pseudorandom sequences generated from a linear feedback shift register (LFSR). Crosstalk is avoided by using transmitted signals coded by different M-sequences generated from different LFSRs. In the case of lower-order M-sequences, however, the number of measurement channels corresponding to the pattern of the LFSR is not enough. In this paper, pulse compression using linear-frequency-modulated (LFM) signals coded by M-sequences has been proposed. The coding of LFM signals by the same M-sequence can produce different transmitted signals and increase the number of measurement channels. In the proposed method, however, the truncation noise in autocorrelation functions and the interference noise in cross-correlation functions degrade the SNRs of received echoes. Therefore, autocorrelation properties and cross-correlation properties in all patterns of combinations of coded LFM signals are evaluated.

  15. Measurement of Trap Length for an Optical Trap

    NASA Technical Reports Server (NTRS)

    Wrbanek, Susan Y.

    2009-01-01

    The trap length along the beam axis for an optical trap formed with an upright, oil-immersion microscope was measured. The goals for this effort were twofold. It was deemed useful to understand the depth to which an optical trap can reach for purposes of developing a tool to assist in the fabrication of miniature devices. Additionally, it was desired to know whether the measured trap length favored one or the other of two competing theories to model an optical trap. The approach was to trap a microsphere of known size and mass and raise it from its initial trap position. The microsphere was then dropped by blocking the laser beam for a pre-determined amount of time. Dropping the microsphere in a free-fall mode from various heights relative to the coverslip provides an estimate of how the trapping length changes with depth in water in a sample chamber on a microscope slide. While it was not possible to measure the trap length with sufficient precision to support any particular theory of optical trap formation, it was possible to find regions where the presence of physical boundaries influenced optical traps, and determine that the trap length, for the apparatus studied, is between 6 and 7 m. These results allow more precise control using optical micromanipulation to assemble miniature devices by providing information about the distance over which an optical trap is effective.

  16. CORRELATION OF H-MODE BARRIER WIDTH AND NEUTRAL PENETRATION LENGTH

    SciTech Connect

    GROEBNER,RJ; MAHDAVI,MA; LEONARD,AW; OSBORNE,TH; WOLF,NS; PORTER,GD; STANGEBY,PC; BROOKS,NH; COLCHIN,RJ; HEIDBRINK,WW; LUCE,TC; MCKEE,GR; OWEN,LW; WANG,G; WHYTE,DG

    2002-09-01

    OAK A271 CORRELATION OF H-MODE BARRIER WIDTH AND NEUTRAL PENETRATION LENGTH. Pedestal studies in DIII-D find a good correlation between the width of the H-mode density barrier and the neutral penetration length. These results are obtained by comparing experimental density profiles to the predictions of an analytic model for the profile, obtained from the particle continuity equations for electrons and deuterium atoms. In its range of validity (edge temperature between 40-500 eV), the analytic model quantitatively predicts the observed decrease of the width as the pedestal density increases, the observed strong increase of the gradient of the density as the pedestal density increases and the observation that L-mode and H-mode profiles with the same pedestal density have very similar shapes. The width of the density barrier, measured from the edge of the electron temperature barrier, is the lower limit for the observed width of the temperature barrier. These results support the hypothesis that particle fueling provides the dominant control for the size of the H-mode transport barrier.

  17. What can we learn about a dynamical length scale in glasses from measurements of surface mobility?

    NASA Astrophysics Data System (ADS)

    Forrest, J. A.

    2013-08-01

    We consider the ability of recent measurements on the size of a liquid-like mobile surface region in glasses to provide direct information on the length scale of enhanced surface mobility. While these quantities are strongly related there are important distinctions that limit the ability of measurements to quantify the actual length over which the surface properties change from surface to bulk-like. In particular, we show that for temperatures near the bulk glass transition, measurements of a liquid-like mobile layer may have very limited predictive power when it comes to determining the temperature dependent length scale of enhanced surface mobility near the glass transition temperature. This places important limitations on the ability of measurements of such enhanced surface dynamics to contribute to discussion on the length scale for dynamical correlation in glassy materials.

  18. A Systematic Comparison of Mathematical Models for Inherent Measurement of Ciliary Length: How a Cell Can Measure Length and Volume

    PubMed Central

    Ludington, William B.; Ishikawa, Hiroaki; Serebrenik, Yevgeniy V.; Ritter, Alex; Hernandez-Lopez, Rogelio A.; Gunzenhauser, Julia; Kannegaard, Elisa; Marshall, Wallace F.

    2015-01-01

    Cells control organelle size with great precision and accuracy to maintain optimal physiology, but the mechanisms by which they do so are largely unknown. Cilia and flagella are simple organelles in which a single measurement, length, can represent size. Maintenance of flagellar length requires an active transport process known as intraflagellar transport, and previous measurements suggest that a length-dependent feedback regulates intraflagellar transport. But the question remains: how is a length-dependent signal produced to regulate intraflagellar transport appropriately? Several conceptual models have been suggested, but testing these models quantitatively requires that they be cast in mathematical form. Here, we derive a set of mathematical models that represent the main broad classes of hypothetical size-control mechanisms currently under consideration. We use these models to predict the relation between length and intraflagellar transport, and then compare the predicted relations for each model with experimental data. We find that three models—an initial bolus formation model, an ion current model, and a diffusion-based model—show particularly good agreement with available experimental data. The initial bolus and ion current models give mathematically equivalent predictions for length control, but fluorescence recovery after photobleaching experiments rule out the initial bolus model, suggesting that either the ion current model or a diffusion-based model is more likely correct. The general biophysical principles of the ion current and diffusion-based models presented here to measure cilia and flagellar length can be generalized to measure any membrane-bound organelle volume, such as the nucleus and endoplasmic reticulum. PMID:25809250

  19. Developing Measurement Concepts within Context: Children's Representations of Length

    ERIC Educational Resources Information Center

    MacDonald, Amy; Lowrie, Tom

    2011-01-01

    This article presents data gathered from an investigation which focused on the experiences children have with measurement in the early years of schooling. The focus of this article is children's understandings of length at this early stage. 32 children aged 4-6 years at an Australian primary school were asked to draw a ruler and describe their…

  20. Measurement accuracy and reliability of tooth length on conventional and CBCT reconstructed panoramic radiographs

    PubMed Central

    Flores-Mir, Carlos; Rosenblatt, Mark R; Major, Paul W.; Carey, Jason P.; Heo, Giseon

    2014-01-01

    INTRODUCTION: This in vivo study assessed accuracy and reliability of tooth length measurements obtained from conventional panoramic radiographs and CBCT panoramic reconstructions to that of a digital caliper (gold standard). METHODS: The sample consisted of subjects who had CBCT and conventional panoramic radiographic imaging and who required maxillary premolar extraction for routine orthodontic treatment. A total of 48 teeth extracted from 26 subjects were measured directly with digital calipers. Radiographic images were scanned and digitally measured in Dolphin 3D software. Accuracy of tooth length measurements made by CBCT panoramic reconstructions, conventional panoramic radiographs and digital caliper (gold standard) were compared to each other by repeated measures one-way ANOVA with Bonferroni correction and by single measures intraclass correlation coefficient. RESULTS: Repeated root length measures with digital calipers, panoramic radiographs and CBCT constructed panoramic-like images were all individually highly reliable. Compared to the caliper (gold standard), tooth measurements obtained from conventional panoramic radiographs were on average 6.3 mm (SD = 2.0 mm) longer, while tooth measurements from CBCT panoramic reconstructions were an average of 1.7 mm (SD = 1.2 mm) shorter. CONCLUSIONS: In comparison to actual tooth lengths, conventional panoramic radiographs were relatively inaccurate, overestimating the lengths by 29%, while CBCT panoramic reconstructions underestimated the lengths by 4%. PMID:25715716

  1. Alignment techniques required by precise measurement of effective focal length

    NASA Technical Reports Server (NTRS)

    Wise, T. D.

    1980-01-01

    The characteristics of false color imagery produced by instrumentation on earth resource mapping satellites are examined. The spatial fidelity of the imagery is dependent upon the geometric accuracy (GA) and the band-to-band registration (BBR) with which the telescope instrument is assembled. BBR and GA require knowledge of telescope effective focal length (EFL) to one part in 10,000 in order that the next generation of earth mappers be able to carry out their missions. The basis for this level of precision is briefly considered, and a description is given of the means by which such precise EFL measurements have been carried out. Attention is given to accuracy requirements, the technique used to measure effective focal length, possible sources of error in the EFL measurement, approaches for eliminating errors, and the results of the efforts to control measurement errors in EFL determinations.

  2. Minimal length in quantum gravity and gravitational measurements

    NASA Astrophysics Data System (ADS)

    Farag Ali, Ahmed; Khalil, Mohammed M.; Vagenas, Elias C.

    2015-10-01

    The existence of a minimal length is a common prediction of various theories of quantum gravity. This minimal length leads to a modification of the Heisenberg uncertainty principle to a Generalized Uncertainty Principle (GUP). Various studies showed that a GUP modifies the Hawking radiation of black holes. In this paper, we propose a modification of the Schwarzschild metric based on the modified Hawking temperature derived from the GUP. Based on this modified metric, we calculate corrections to the deflection of light, time delay of light, perihelion precession, and gravitational redshift. We compare our results with gravitational measurements to set an upper bound on the GUP parameter.

  3. Effective crack lengths by compliance measurement for ARALL-2 laminates

    NASA Technical Reports Server (NTRS)

    Wilson, Christopher D.; Wilson, Dale A.

    1991-01-01

    As a means of determining a stress intensity factor solution, the compliance properties of an ARALL-2 laminated-sheet composite were investigated. Fatigue crack growth rate (FCGR) tests were conducted on middle crack tension (MT) specimens fabricated from a layup consisting of three sheets of 2024-T3 aluminum bonded together with unidirectional aramid fibers embedded in epoxy. Excellent fatigue crack growth properties are obtained by the presence of unbroken aramid fibers in the wake of the crack tip. These unbroken fibers act as a bridging mechanism to inhibit further crack growth. To quantify the effect of maximum fatigue load on compliance, a series of FCGR tests were performed. Effective crack lengths were determined to be at least 10 mm shorter than surface measured crack lengths for a 76-mm-wide specimen. The bridging zone was estimated to be at least 5 mm. Compliance and stress intensity factor as functions of effective crack length were determined.

  4. Reducing trial length in force platform posturographic sleep deprivation measurements

    NASA Astrophysics Data System (ADS)

    Forsman, P.; Hæggström, E.; Wallin, A.

    2007-09-01

    Sleepiness correlates with sleep-related accidents, but convenient tests for sleepiness monitoring are scarce. The posturographic test is a method to assess balance, and this paper describes one phase of the development of a posturographic sleepiness monitoring method. We investigated the relationship between trial length and accuracy of the posturographic time-awake (TA) estimate. Twenty-one healthy adults were kept awake for 32 h and their balance was recorded, 16 times with 30 s trials, as a function of TA. The balance was analysed with regards to fractal dimension, most common sway amplitude and time interval for open-loop stance control. While a 30 s trial allows estimating the TA of individual subjects with better than 5 h accuracy, repeating the analysis using shorter trial lengths showed that 18 s sufficed to achieve the targeted 5 h accuracy. Moreover, it was found that with increasing TA, the posturographic parameters estimated the subjects' TA more accurately.

  5. Developing measurement concepts within context: Children's representations of length

    NASA Astrophysics Data System (ADS)

    MacDonald, Amy; Lowrie, Tom

    2011-03-01

    This article presents data gathered from an investigation which focused on the experiences children have with measurement in the early years of schooling. The focus of this article is children's understandings of length at this early stage. 32 children aged 4-6 years at an Australian primary school were asked to draw a ruler and describe their drawing, once in February at the beginning of school, and again in November towards the end of their first year of school. The drawings and their accompanying descriptions are classified within a matrix which, informed by Bronfenbrenner's ecological theory and literature regarding the development of length concepts, considers conceptual understanding and contextual richness. The responses revealed that children have a good understanding of length at the start of school, but that as their ability to contextualise develops so too does their conceptual understanding. This article suggests that participation in tasks such as these allows children to create their own understandings of length in meaningful ways. Additionally, the task and its matrix of analysis provide an assessment strategy for identifying children's understandings about length and the contexts in which these understandings develop.

  6. Length Scale Correlations of Cellular Microstructures in Directionally Solidified Binary System

    SciTech Connect

    Yunxue Shen

    2002-06-27

    In a cellular array, a range of primary spacing is found to be stable under given growth conditions. Since a strong coupling of solute field exists between the neighboring cells, primary spacing variation should also influence other microstructure features such as cell shape and cell length. The existence of multiple solutions is examined in this study both theoretically as well as experimentally. A theoretical model is developed that identifies and relates four important microstructural lengths, which are found to be primary spacing, tip radius, cell width and cell length. This general microstructural relationship is shown to be valid for different cells in an array as well as for other cellular patterns obtained under different growth conditions. The unique feature of the model is that the microstructure correlation does not depend on composition or growth conditions since these variables scale microstructural lengths to satisfy the relationship obtained in this study. Detailed directional solidification experimental studies have been carried out in the succinonitrile-salol system to characterize and measure these four length scales. Besides the validation of the model, experimental results showed additional scaling laws to be present. In the regime where only a cellular structure is formed, the shape of the cell, the cell tip radius and the length of the cell are all found to scale individually with the local primary spacing. The presence of multiple solutions of primary spacing is also shown to influence the cell-dendrite transition that is controlled not only by the processing variables (growth velocity, thermal gradient and composition) but also by the local cell spacing. The cell-dendrite transition was found not to be sharp, but occurred over a range of processing conditions. Two critical conditions have been identified such that only cells are present below lower critics condition, and only dendrites are formed above the upper critics condition. Between

  7. Length Scale Correlations of Cellular Microstructures in Directionally Solidified Binary System

    SciTech Connect

    Yunxue Shen

    2002-08-01

    In a cellular array, a range of primary spacing is found to be stable under given growth conditions. Since a strong coupling of solute field exists between the neighboring cells, primary spacing variation should also influence other microstructure features such as cell shape and cell length. The existence of multiple solutions is examined in this study both theoretically as well as experimentally. A theoretical model is developed that identifies and relates four important microstructural lengths, which are found to be primary spacing, tip radius, cell width and cell length. This general microstructural relationship is shown to be valid for different cells in an array as well as for other cellular patterns obtained under different growth conditions. The unique feature of the model is that the microstructure correlation does not depend on composition or growth conditions since these variables scale microstructural lengths to satisfy the relationship obtained in this study. Detailed directional solidification experimental studies have been carried out in the succinonitrile-salol system to characterize and measure these four length scales. Besides the validation of the model, experimental results showed additional scaling laws to be present. In the regime where only a cellular structure is formed, the shape of the cell, the cell tip radius and the length of the cell are all found to scale individually with the local primary spacing. The presence of multiple solutions of primary spacing is also shown to influence the cell-dendrite transition that is controlled not only by the processing variables (growth velocity, thermal gradient and composition) but also by the local cell spacing. The cell-dendrite transition was found not to be sharp, but occurred over a range of processing conditions. Two critical conditions have been identified such that only cells are present below lower critics condition, and only dendrites are formed above the upper critics condition. Between

  8. Electron Bunch Length Measurement for LCLS at SLAC

    SciTech Connect

    Zelazny, M.; Allison, S.; Chevtsov, Sergei; Emma, P.; Kotturi, K.d.; Loos, H.; Peng, S.; Rogind, D.; Straumann, T.; /SLAC

    2007-10-04

    At Stanford Linear Accelerator Center (SLAC) a Bunch Length Measurement system has been developed to measure the length of the electron bunch for its new Linac Coherent Light Source (LCLS). This destructive measurement uses a transverse-mounted RF deflector (TCAV) to vertically streak the electron beam and an image taken with an insertable screen and a camera. The device control software was implemented with the Experimental Physics and Industrial Control System (EPICS) toolkit. The analysis software was implemented in Matlab{trademark} using the EPICS/Channel Access Interface for Scilab{trademark} and Matlab{trademark} (labCA). This architecture allowed engineers and physicists to develop and integrate their control and analysis without duplication of effort.

  9. Repeat Measurement of Cervical Length in Women with Threatened Preterm Labor

    PubMed Central

    Wagner, P.; Sonek, J.; Heidemeyer, M.; Schmid, M.; Abele, H.; Hoopmann, M.; Kagan, K. O.

    2016-01-01

    Objective: To examine the value of a repeat measurement some days after the first cervical length measurement done at the time of preterm contractions. Study Design: Retrospective study involving women with singleton pregnancies who presented with preterm contractions at 24 to 33 + 6 weeks of gestation. The cervical length was measured at the time of presentation and some days afterwards. Results: The study population consisted of 17 cases with a preterm delivery within 14 days and 288 uneventful pregnancies. Univariate logistic regression analysis indicated a significant correlation between delivery within 14 days and both, the first and second cervical length measurements as well as the difference between the two measurements. Up to a false positive rate of 20 %, ROC curve analysis showed an improved detection rate for preterm delivery by inluding both measurements. At a false positive rate of 10 % – which corresponds to a first and second cervical length of 10 and 9 mm – the detection rate was 17.6 % with the first cervical length measurement, 47.0 % with the second and 52.9 % if the difference between both measurements was added. Conclusion: Our results indicate that in women with symptoms of preterm labor it is worth to repeat the measurement some days later and to take into account the difference between both measurements.

  10. Negative correlation between age of subjects and length of the appendix in Bangladeshi males

    PubMed Central

    Bakar, Sheikh Muhammad Abu; Shamim, Manjare; Alam, Gazi Mahabubul

    2013-01-01

    Introduction The anatomy of the vermiform appendix shows variations in its macroscopic dimensions some of which have potential to influence the clinical aspects of the appendix. Anatomical studies on the appendix using people in Bangladesh as a sample are limited and fall short of producing any standardized anthropometric data. This study is predominantly a cross-sectional observational study which also uses some statistical analysis to understand the relationships amongst variables. Material and methods Fifty-six adult male postmortem appendices and adnexa were examined for macroscopic features. Possible interrelationships among the variables were assessed through statistical analysis. The age of the samples ranged from 18 to 67 years. The most common position of the appendix was retrocolic (53.57%) followed by pelvic (30.35%), postileal (12.5%), and subcaecal (3.5%). Results In most cases (62.5%) the mesoappendix did not reach the tip of the appendix. The appendicular length varied from 6.00 cm to 16.30 cm with mean (± SD) and median value of 10.21 ±2.50 cm and 10.00 cm respectively. The base of the appendix was 1.90 to 3.80 cm away from the ileocaecal junction. The other macroscopic measurements of the appendix were taken at the base, at the midzone and at the tip of the appendix and the mean of the three measurements was considered as the overall value. Thus, the overall external diameter varied between 0.32 cm and 0.83 cm. Assessment of possible correlations amongst different variables revealed a significant negative correlation between the age of the subjects and the length of the appendix. Conclusions The data of the present study may provide a baseline along with some previous data in the standardization of the anthropometric information regarding the vermiform appendix of Bangladeshi males. PMID:23515519

  11. Absolute length measurement using manually decided stereo correspondence for endoscopy

    NASA Astrophysics Data System (ADS)

    Sasaki, M.; Koishi, T.; Nakaguchi, T.; Tsumura, N.; Miyake, Y.

    2009-02-01

    In recent years, various kinds of endoscope have been developed and widely used to endoscopic biopsy, endoscopic operation and endoscopy. The size of the inflammatory part is important to determine a method of medical treatment. However, it is not easy to measure absolute size of inflammatory part such as ulcer, cancer and polyp from the endoscopic image. Therefore, it is required measuring the size of those part in endoscopy. In this paper, we propose a new method to measure the absolute length in a straight line between arbitrary two points based on the photogrammetry using endoscope with magnetic tracking sensor which gives camera position and angle. In this method, the stereo-corresponding points between two endoscopic images are determined by the endoscopist without any apparatus of projection and calculation to find the stereo correspondences, then the absolute length can be calculated on the basis of the photogrammetry. The evaluation experiment using a checkerboard showed that the errors of the measurements are less than 2% of the target length when the baseline is sufficiently-long.

  12. Vibration transfer mobility measurements using maximum length sequences

    NASA Astrophysics Data System (ADS)

    Singleton, Herbert L.

    2005-09-01

    Vibration transfer mobility measurements are required under Federal Transit Administration guidelines when developing detailed predictions of ground-borne vibration for rail transit systems. These measurements typically use a large instrumented hammer to generate impulses in the soil. These impulses are measured by an array of accelerometers to characterize the transfer mobility of the ground in a localized area. While effective, these measurements often make use of heavy, custom-engineered equipment to produce the impulse signal. To obtain satisfactory signal-to-noise ratios, it is necessary to generate multiple impulses to generate an average value, but this process involves considerable physical labor in the field. To address these shortcomings, a transfer mobility measurement system utilizing a tactile transducer and maximum length sequences (MLS) was developed. This system uses lightweight off-the-shelf components to significantly reduce the weight and cost of the system. The use of MLS allows for adequate signal-to-noise ratio from the tactile transducer, while minimizing the length of the measurement. Tests of the MLS system show good agreement with the impulse-based method. The combination of the cost savings and reduced weight of this new system facilitates transfer mobility measurements that are less physically demanding, and more economical when compared with current methods.

  13. Distribution of the lateral correlation length in GaN epitaxial layers

    NASA Astrophysics Data System (ADS)

    Kozlowski, J.; Paszkiewicz, R.; Korbutowicz, R.; Tlaczala, M.

    2001-12-01

    GaN structures belong to the most popular wide-bandgap semiconductors. Large lattice mismatch existing between the layer and substrates (3.5% for SiC and even 16% in the case of sapphire substrate) results in structures with a large number of defects. The typical GaN epitaxial layer consists of dislocation-free regions with lateral dimensions equal to a few hundred nanometers. The dislocation density changes from 10 8 cm -2 inside the grains to 10 10 cm -2 in the grain boundaries. The average value of the lateral correlation lengths (coherence wavelength) seems to be not quite satisfactory. Particularly, it is connected with lateral direction, because the vertical length is approximately equal to the thickness of the epitaxial layer. This paper presents the new approach for the determination of GaN crystallites dislocation-free block size distributions. This method is based on the X-ray peak profile analysis and solution of the Fredholm integral equation. The necessary peaks are obtained from the high-resolution X-ray diffractometry measurements. The obtained results have been shown for the various samples: GaN layers grown on low temperature buffer layer (GaN or AlN). Very interesting results were obtained in the first case, where two different sizes of the blocks appear.

  14. Electron bunch length measurement at the Vanderbilt FEL

    SciTech Connect

    Amirmadhi, F.; Brau, C.A.; Mendenhall, M.

    1995-12-31

    During the past few years, a number of experiments have been performed to demonstrate the possibility to extract the longitudinal charge distribution from spectroscopic measurements of the coherent far-infrared radiation emitted as transition radiation or synchrotron radiation. Coherent emission occurs in a spectral region where the wavelength is comparable to or longer than the bunch length, leading to an enhancement of the radiation intensity that is on the order of the number of particles per bunch, as compared to incoherent radiation. This technique is particularly useful in the region of mm and sub-mm bunch lengths, a range where streak-cameras cannot be used for beam diagnostics due to their limited time resolution. Here we report on experiments that go beyond the proof of principle of this technique by applying it to the study and optimization of FEL performance. We investigated the longitudinal bunch length of the Vanderbilt FEL by analyzing the spectrum of coherent transition radiation emitted by the electron bunches. By monitoring the bunch length while applying a bunch-compression technique, the amount of the compression could be easily observed. This enabled us to perform a systematic study of the FEL performance, especially gain and optical pulse width, as a function of the longitudinal electron distribution in the bunch. The results of this study will be presented and discussed.

  15. The correlation between intron length and recombination in drosophila. Dynamic equilibrium between mutational and selective forces.

    PubMed

    Comeron, J M; Kreitman, M

    2000-11-01

    Intron length is negatively correlated with recombination in both Drosophila melanogaster and humans. This correlation is not likely to be the result of mutational processes alone: evolutionary analysis of intron length polymorphism in D. melanogaster reveals equivalent ratios of deletion to insertion in regions of high and low recombination. The polymorphism data do reveal, however, an excess of deletions relative to insertions (i.e., a deletion bias), with an overall deletion-to-insertion events ratio of 1.35. We propose two types of selection favoring longer intron lengths. First, the natural mutational bias toward deletion must be opposed by strong selection in very short introns to maintain the minimum intron length needed for the intron splicing reaction. Second, selection will favor insertions in introns that increase recombination between mutations under the influence of selection in adjacent exons. Mutations that increase recombination, even slightly, will be selectively favored because they reduce interference among selected mutations. Interference selection acting on intron length mutations must be very weak, as indicated by frequency spectrum analysis of Drosophila intron length polymorphism, making the equilibrium for intron length sensitive to changes in the recombinational environment and population size. One consequence of this sensitivity is that the advantage of longer introns is expected to decrease inversely with the rate of recombination, thus leading to a negative correlation between intron length and recombination rate. Also in accord with this model, intron length differs between closely related Drosophila species, with the longest variant present more often in D. melanogaster than in D. simulans. We suggest that the study of the proposed dynamic model, taking into account interference among selected sites, might shed light on many aspects of the comparative biology of genome sizes including the C value paradox. PMID:11063693

  16. Interaural correlations in normal and traumatized cochleas: length and sensory cell loss

    SciTech Connect

    Bohne, B.A.; Bozzay, D.G.; Harding, G.W.

    1986-12-01

    Sizable intraspecies variations have been found in both the length of the organ of Corti (OC) and the amount of damage resulting from exposure to a particular ototraumatic agent. These variations have made it difficult to address certain research questions such as the susceptibility of the previously injured ear to further damage. If intra-animal correlation is high, the variability problem could be circumvented by using the two ears from a given animal for different aspects of the same study. Therefore, correlation coefficients were calculated for OC length and for percentage of missing inner (IHCs) and outer hair cells (OHCs) in a large sample of chinchillas which included controls and animals which had been exposed to noise or treated with ionizing radiation. The correlation coefficients were +0.96 for OC length, +0.93 for IHC loss, and +0.97 for OHC loss.

  17. Measurement of the hot electron attenuation length of copper

    NASA Astrophysics Data System (ADS)

    Garramone, J. J.; Abel, J. R.; Sitnitsky, I. L.; Zhao, L.; Appelbaum, I.; LaBella, V. P.

    2010-02-01

    Ballistic electron emission microscopy is utilized to investigate the hot-electron scattering properties of Cu through Cu/Si(001) Schottky diodes. A Schottky barrier height of 0.64±0.02 eV and a hot-electron attenuation length of 33.4±2.9 nm are measured at a tip bias of 1.0 eV and a temperature of 80 K. The dependence of the attenuation length with tip bias is fit to a Fermi liquid model that allows extraction of the inelastic and elastic scattering components. This modeling indicates that elastic scattering due to defects, grain boundaries, and interfaces is the dominant scattering mechanism in this energy range.

  18. Measurement of radon diffusion length in thin membranes.

    PubMed

    Malki, A; Lavi, N; Moinester, M; Nassar, H; Neeman, E; Piasetzky, E; Steiner, V

    2012-07-01

    Building regulations in Israel require the insulating of buildings against radon (222)Rn penetration from soil. In radon-prone areas membranes stretched between the soil and the building foundation are used, together with sealing other possible penetration routes. Designing the radon mitigation procedure requires checking that all sealing materials are practically, radon tight, having a thickness of at least three times the radon diffusion length. In this work, a very simple technique to evaluate the radon diffusion length in thin membranes, using a radon source of known activity and an activated charcoal canister as radon detector is presented. The theoretical formalism and measurement results for polyethylene membranes of different densities obtained in a recent comparison exercise are presented. PMID:22232779

  19. Real time bunch length measurements in the SLC linac

    SciTech Connect

    Sheppard, J.C.; Clendenin, J.E.; James, M.B.; Miller, R.H.; Ross, M.C.

    1985-02-01

    The longitudinal charge distribution of bunches accelerated in the Stanford Linear Collider (SLC) linac will strongly affect the performance of the Collider. Bunch lengths are chosen in a balance between the deleterious effects of longitudinal and transverse wakefields. The former impacts on the beam energy spread whereas the latter is important to the transverse emittance. Two bunch length measurement ports have been installed in the SLC linac: one in the injector region and one after the emittance damping ring to linac reinjection point. These ports utilize a fused quartz Cerenkov radiator in conjunction with an electrooptic streak camera to permit real time monitoring of single s-band buckets with a resolution of several picoseconds. The design of the radiators and light collection optics is discussed with an emphasis on those issues important to high resolution. Experimental results are presented. 7 refs., 4 figs.

  20. Direct calculation of correlation length based on quasi-cumulant method

    NASA Astrophysics Data System (ADS)

    Fukushima, Noboru

    2014-03-01

    We formulate a method of directly obtaining a correlation length without full calculation of correlation functions, as a high-temperature series. The method is based on the quasi-cumulant method, which was formulated by the author in J. Stat. Phys. 111, 1049-1090 (2003) as a complementary method for the high-temperature series expansion originally for an SU(n) Heisenberg model, but is applicable to general spin models according to our recent reformulation. A correlation function divided by its lowest-order nonzero contribution has properties very similar to a generating function of some kind of moments, which we call quasi-moments. Their corresponding quasi-cumulants can be also derived, whose generating function is related to the correlation length. In addition, applications to other numerical methods such as the quantum Monte Carlo method are also discussed. JSPS KAKENHI Grant Number 25914008.

  1. The Effect of Age, Gender, Refractive Status and Axial Length on the Measurements of Hertel Exophthalmometry

    PubMed Central

    Karti, Omer; Selver, Ozlem B; Karahan, Eyyup; Zengin, Mehmet O; Uyar, Murat

    2015-01-01

    Purpose : To evaluate the normal distribution of exophthalmometric values in Turkish adult population and the effect of age, gender, refractive status and axial length on globe position. Methods : One hundred and twenty-two males and 114 healthy females with age ranging from 18 to 87 years were included in the study. The study population was recruited from patients presenting to our institution for routine refractive examination. Hertel exophthalmometer was used to measure the degree of ocular protrusion. Effect of age, refractive error, interpupillary distance, and axial length on globe position was detected with linear regression analyses. Results : The mean Hertel exophthalmometric size was 15.7+2.6 mm (range; 11 to 21 mm). The mean value for males was 16.1±2.6 mm (range; 11 to 21 mm), and for females 15.5±2.6 mm (range; 11 to 20 mm). The mean distance between the lateral rims of the orbit was 102 + 5.1 mm (range; 88 to 111mm). The mean exophthalmometric values were not statistically different in males and females. Age and mean spherical equivalents were negatively correlated with exophthalmometric measurements. Axial length was positively correlated with exophthalmometric measurements. Conclusion : The exophthalmometric measurement of the eye is affected by the age, spherical equivalent and the axial length. Standard normative values of the Hertel exophthalmometric measurements should be reevaluated with larger samples. PMID:26089994

  2. Diffusion length measurements of thin amorphous silicon layers

    NASA Astrophysics Data System (ADS)

    van den Heuvel, J. C.; van Oort, R. C.; Geerts, M. J.

    1989-02-01

    A new method for the analysis of diffusion length measurements by the Surface Photovoltage (SPV) method is presented. It takes into account the effect of the reflection of light from the back contact in thin layers and the effect of a finite bandwidth of the used interference filters. The model was found to agree with experiments on thin amorphous silicon (a-Si:H) layers. It is shown that in the region were these effects are negligible this method is equivalent to the standard method.

  3. Complex transition metal hydrides: linear correlation of countercation electronegativity versus T-D bond lengths.

    PubMed

    Humphries, T D; Sheppard, D A; Buckley, C E

    2015-06-30

    For homoleptic 18-electron complex hydrides, an inverse linear correlation has been established between the T-deuterium bond length (T = Fe, Co, Ni) and the average electronegativity of the metal countercations. This relationship can be further employed towards aiding structural solutions and predicting physical properties of novel complex transition metal hydrides. PMID:26077621

  4. Measurement of the Coherent Neutron Scattering Length of 3He

    PubMed Central

    Ketter, W.; Heil, W.; Badurek, G.; Baron, M.; Loidl, R.; Rauch, H.

    2005-01-01

    By means of neutron interferometry the s-wave neutron scattering length of the 3He nucleus was re-measured at the Institut Laue-Langevin (ILL). Using a skew symmetrical perfect crystal Si-interferometer and a linear twin chamber cell, false phase shifts due to sample misalignment were reduced to a negligible level. Simulation calculations suggest an asymmetrically alternating measuring sequence in order to compensate for systematic errors caused by thermal phase drifts. There is evidence in the experiment’s data that this procedure is indeed effective. The neutron refractive index in terms of Sears’ exact expression for the scattering amplitude has been analyzed in order to evaluate the measured phase shifts. The result of our measurement, b′c = (6.000 ± 0.009) fm, shows a deviation towards a greater value compared to the presently accepted value of b′c = (5.74 ± 0.07) fm, confirming the observation of the partner experiment at NIST. On the other hand, the results of both precision measurements at NIST and ILL exhibit a serious 12σ (12 standard uncertainties) deviation, the reason for which is not clear yet.

  5. Comparison of three methods of measuring the atmospheric coherence length

    NASA Astrophysics Data System (ADS)

    Slavin, Ann C.; Wells, Ann L.; Fugate, Robert Q.; Fried, David L.; Drexler, James J.

    1997-09-01

    In the fall of 1996, we had the opportunity to mneasure the atmospheric coherence length (Fried's r0 parameter) at the STarfire Optical Range using three instruments. Each instrument measured r0 using a different theory and technique. The first instrument, designed and built by Dr. Donald Walters of the Naval Postgraduate School, is based on measuring the MTF of the atmosphere using a stellar image on a one dimensional detector. The second instrument, designed and built by Lockheed Martin engineers at White Sands Missile Range, is based on measuring the differential motion of stellar images. The third technique in this study used short exposure star images taken through the 1.5m telescope and processed by matching the images to shrot exposure theory values of r0. All of the instruments were located at the STarfire Optical Range and data were collected during both day and night hours. This paper presents the results of these measurements and discusses the different techniques in terms of the results obtained.

  6. SAGE II aerosol correlative observations - Profile measurements

    NASA Technical Reports Server (NTRS)

    Osborn, M. T.; Rosen, J. M.; Mccormick, M. P.; Wang, Pi-Huan; Livinfston, J. M.

    1989-01-01

    Profiles of the aerosol extinction measurements from the Stratospheric Aerosol and Gas Experiment (SAGE) II are compared with profiles from five correlative experiments between November 1984 and July 1986. The correlative profiles were derived from six-channel dustsonde measurements and two-wavelength lidar backscatter data. The correlation between the dustsonde- and lidar-derived measurements and the SAGE II data is good, validating the SAGE II lower stratospheric aerosol extinction measurements.

  7. Leukocyte Telomere Length in Major Depression: Correlations with Chronicity, Inflammation and Oxidative Stress - Preliminary Findings

    PubMed Central

    Wolkowitz, Owen M.; Mellon, Synthia H.; Epel, Elissa S.; Lin, Jue; Dhabhar, Firdaus S.; Su, Yali; Reus, Victor I.; Rosser, Rebecca; Burke, Heather M.; Kupferman, Eve; Compagnone, Mariana; Nelson, J. Craig; Blackburn, Elizabeth H.

    2011-01-01

    Background Depression is associated with an unusually high rate of aging-related illnesses and early mortality. One aspect of “accelerated aging” in depression may be shortened leukocyte telomeres. When telomeres critically shorten, as often occurs with repeated mitoses or in response to oxidation and inflammation, cells may die. Indeed, leukocyte telomere shortening predicts early mortality and medical illnesses in non-depressed populations. We sought to determine if leukocyte telomeres are shortened in Major Depressive Disorder (MDD), whether this is a function of lifetime depression exposure and whether this is related to putative mediators, oxidation and inflammation. Methodology Leukocyte telomere length was compared between 18 unmedicated MDD subjects and 17 controls and was correlated with lifetime depression chronicity and peripheral markers of oxidation (F2-isoprostane/Vitamin C ratio) and inflammation (IL-6). Analyses were controlled for age and sex. Principal Findings The depressed group, as a whole, did not differ from the controls in telomere length. However, telomere length was significantly inversely correlated with lifetime depression exposure, even after controlling for age (p<0.05). Average telomere length in the depressed subjects who were above the median of lifetime depression exposure (≥9.2 years' cumulative duration) was 281 base pairs shorter than that in controls (p<0.05), corresponding to approximately seven years of “accelerated cell aging.” Telomere length was inversely correlated with oxidative stress in the depressed subjects (p<0.01) and in the controls (p<0.05) and with inflammation in the depressed subjects (p<0.05). Conclusions These preliminary data indicate that accelerated aging at the level of leukocyte telomeres is proportional to lifetime exposure to MDD. This might be related to cumulative exposure to oxidative stress and inflammation in MDD. This suggest that telomere shortening does not antedate depression and is

  8. Total diesel exhaust particulate length measurements using a modified household smoke alarm ionization chamber.

    PubMed

    Vojtisek-Lom, Michal

    2011-02-01

    To evaluate the effectiveness of various means to combat the negative health effects of ultrafine particles emitted by internal combustion engines, a reliable, low-cost instrument for dynamic measurements of the exhaust emissions of ultrafine particulate matter (PM) is needed. In this study, an ordinary ionization-type building smoke detector was modified to serve as a measuring ionization chamber and utilized for dynamic measurements of PM emissions from diesel engines. When used with diluted exhaust, the readings show an excellent correlation with total particulate length. The instrument worked well with raw and diluted exhaust and with varying emission levels and is well suitable for on-board use. PMID:21387930

  9. Neutron depolarization study on the magnetic correlation length of nickel ferrite with different packing densities

    NASA Astrophysics Data System (ADS)

    Lee, Chih-Hao; Chang, Hsin-Ho; Su, Hui-Chia; Wu, Yu-Han; Hu, Chih-Wei; Chang, L. J.; Ioffe, A.; Bussmann, K.; Brückel, Th.

    2009-09-01

    The magnetic correlation length of a mixed nickel ferrite powder was studied by a newly commissioned depolarized neutron beamline at the W3 port of Tsing Hua Open Pool Reactor (THOR). In this work, Ni ferrite powder samples with different packing densities were studied. The magnetic correlation lengths of the sample were observed to be 2 μm at virgin state and about 3.1 μm at remanent state from the packing density of 20-60%. This magnetic domain size is smaller than particle size. No significant change of domain size at this packing density implies the domain wall motion is hindered by the porosity effectively up to at least 60% of packing density.

  10. Correlation between weighted spectral distribution and average path length in evolving networks.

    PubMed

    Jiao, Bo; Shi, Jianmai; Wu, Xiaoqun; Nie, Yuanping; Huang, Chengdong; Du, Jing; Zhou, Ying; Guo, Ronghua; Tao, Yerong

    2016-02-01

    The weighted spectral distribution (WSD) is a metric defined on the normalized Laplacian spectrum. In this study, synchronic random graphs are first used to rigorously analyze the metric's scaling feature, which indicates that the metric grows sublinearly as the network size increases, and the metric's scaling feature is demonstrated to be common in networks with Gaussian, exponential, and power-law degree distributions. Furthermore, a deterministic model of diachronic graphs is developed to illustrate the correlation between the slope coefficient of the metric's asymptotic line and the average path length, and the similarities and differences between synchronic and diachronic random graphs are investigated to better understand the correlation. Finally, numerical analysis is presented based on simulated and real-world data of evolving networks, which shows that the ratio of the WSD to the network size is a good indicator of the average path length. PMID:26931591

  11. Correlation between weighted spectral distribution and average path length in evolving networks

    NASA Astrophysics Data System (ADS)

    Jiao, Bo; Shi, Jianmai; Wu, Xiaoqun; Nie, Yuanping; Huang, Chengdong; Du, Jing; Zhou, Ying; Guo, Ronghua; Tao, Yerong

    2016-02-01

    The weighted spectral distribution (WSD) is a metric defined on the normalized Laplacian spectrum. In this study, synchronic random graphs are first used to rigorously analyze the metric's scaling feature, which indicates that the metric grows sublinearly as the network size increases, and the metric's scaling feature is demonstrated to be common in networks with Gaussian, exponential, and power-law degree distributions. Furthermore, a deterministic model of diachronic graphs is developed to illustrate the correlation between the slope coefficient of the metric's asymptotic line and the average path length, and the similarities and differences between synchronic and diachronic random graphs are investigated to better understand the correlation. Finally, numerical analysis is presented based on simulated and real-world data of evolving networks, which shows that the ratio of the WSD to the network size is a good indicator of the average path length.

  12. Decadal correlation between crustal deformation and variation in length of day of the Earth

    NASA Astrophysics Data System (ADS)

    Wang, Qing-Liang; Chen, Yun-Tai; Cui, Du-Xin; Wang, Wen-Ping; Liang, Wei-Feng

    2000-11-01

    Recently, in comparing with Earth rotation data, we found some exciting correlation phenomena between length-of-day (LOD) and crustal deformations as well as stress observations in China, the correlation appears most typically on decade time scales and seems to be direction-dependent. As LOD variation induced stress and deformation is far less than the observed ones, we infer that decade variations in crustal deformation and stress are very possibly attributed to the core-mantle coupling process, just like LOD decade variations are attributed to core-mantle coupling. More detailed and extended investigations are going on, and we believe that the similar correlation phenomena should also exist in other part of the world. The LOD-correlated crustal deformations are expected to provide a better constraint on verifying the real core-mantle coupling mechanism, topographic, electromagnetic or gravitational coupling.

  13. Measurement of the Length of an Optical Trap

    NASA Technical Reports Server (NTRS)

    Wrbanek, Susan Y.

    2010-01-01

    NASA Glenn has been involved in developing optical trapping and optical micromanipulation techniques in order to develop a tool that can be used to probe, characterize, and assemble nano and microscale materials to create microscale sensors for harsh flight environments. In order to be able to assemble a sensor or probe candidate sensor material, it is useful to know how far an optical trap can reach; that is, the distance beyond/below the stable trapping point through which an object will be drawn into the optical trap. Typically, to measure the distance over which an optical trap would influence matter in a horizontal (perpendicular to beam propagation) direction, it was common to hold an object in one optical trap, place a second optical trap a known distance away, turn off the first optical trap, and note if the object was moved into the second trap when it was turned on. The disadvantage of this technique is that it only gives information of trap influence distance in horizontal (x y) directions. No information about the distance of the influence of the trap is gained in the direction of propagation of the beam (the z direction). A method was developed to use a time-of-flight technique to determine the length along the propagation direction of an optical trap beam over which an object may be drawn into the optical trap. Test objects (polystyrene microspheres) were held in an optical trap in a water-filled sample chamber and raised to a pre-determined position near the top of the sample chamber. Next, the test objects were released by blocking the optical trap beam. The test objects were allowed to fall through the water for predetermined periods of time, at the end of which the trapping beam was unblocked. It was noted whether or not the test object returned to the optical trap or continued to fall. This determination of the length of an optical trap's influence by this manner assumes that the test object falls through the water in the sample chamber at

  14. Audiogram, body mass, and basilar papilla length: correlations in birds and predictions for extinct archosaurs

    NASA Astrophysics Data System (ADS)

    Gleich, Otto; Dooling, Robert J.; Manley, Geoffrey A.

    2005-12-01

    The inner ear in the group of archosaurs (birds, crocodilians, and extinct dinosaurs) shows a high degree of structural similarity, enabling predictions of their function in extinct species based on relationships among similar variables in living birds. Behavioral audiograms and morphological data on the length of the auditory sensory epithelium (the basilar papilla) are available for many avian species. By bringing different data sets together, we show that body mass and the size of the basilar papilla are significantly correlated, and the most sensitive frequency in a given species is inversely related to the body mass and the length of the basilar papilla. We also demonstrate that the frequency of best hearing is correlated with the high-frequency limit of hearing. Small species with a short basilar papilla hear higher frequencies compared with larger species with a longer basilar papilla. Based on the regression analysis of two significant correlations in living archosaurs (best audiogram frequency vs body mass and best audiogram frequency vs papillar length), we suggest that hearing in large dinosaurs was restricted to low frequencies with a high-frequency limit below 3 kHz.

  15. Cavity length measurement: bias from misalignment and mismatching.

    PubMed

    Reasenberg, Robert D

    2013-11-20

    SR-POEM, the sounding rocket principle of equivalence measurement, uses a set of six tracking-frequency laser gauges operating in Fabry-Perot cavities to determine the relative acceleration of two test masses (TMs) that are chemically different. One end of each cavity is a flat mirror on a TM; the other end is a concave coupling mirror mounted to a common reference plate. The tracking-frequency laser gauges work by locking a variable frequency laser to the cavity by the method of Pound, Drever, and Hall. Because the TMs are unconstrained, they are expected to rotate slightly during measurement. Although the distance measurements are intended to be based on the TEM₀₀ cavity mode, any misalignment will couple into higher-order transverse modes, particularly the TEM₁₀ and TEM₀₁. Light thus coupled will contribute a spurious signal to the cavity locking servo that causes a bias (i.e., a systematic error) in the length determination. The spurious signal proportional to the misalignment has an antisymmetric distribution at the detector and thus has a zero average, but causes a distance bias because of the inhomogeneity of the detector responsivity. To prevent such bias, SR-POEM includes a servo to keep the incoming laser beam aligned with the cavity. The required performance of that alignment servo is less stringent than has already been achieved by other projects. There is also a spurious signal proportional to the square of the misalignment that produces a symmetric distribution at the detector. This signal is also made unimportant by the operation of an alignment servo, even when operating well above the shot noise limit. We also look at the locking of a laser to a high finesse cavity and conclude that the alignment quality sets a bound on the ratio of measurement accuracy to cavity linewidth. PMID:24513772

  16. Urethral length measurement in women during sonographic urethrocystography – an analysis of repeatability and reproducibility

    PubMed Central

    Kociszewski, Jacek; Suzin, Jacek; Dresler, Maria; Surkont, Grzegorz

    2016-01-01

    There has been a rise in the use of sonographic urethrocystography in patients with a full bladder. So far, no publications have been made on the analysis of repeatability and reproducibility of the measurements performed during this procedure. Aim An assessment of repeatability and reproducibility of urethral length measurements during sonographic urethrocystography in females with a full bladder in the introital approach, using real-time two-dimensional transvaginal ultrasound. Material and methods The ultrasound was performed in accordance with a standardized technique in female patients with a full bladder containing 200–300 mL of liquid. A total of 92 patients were included in the analysis. Results The Intraclass Correlation Coefficient for repeatability and reproducibility of urethral length measurements in sonographic urethrocystography ranged between 0.9217 and 0.9873 (p = 0.0000). The analysis of ultrasound urethral length measurements taken by two different physicians at an interval of several months confirmed their very high compatibility (ICC = 0.81, p = 0.000). Conclusions Very good repeatability and reproducibility of urethral length findings during sonographic urethrocystography performed in accordance with the presented technique support the possible use of this type of examination in both clinical practice and research. PMID:27104000

  17. Variability of interconnected wind plants: correlation length and its dependence on variability time scale

    NASA Astrophysics Data System (ADS)

    St. Martin, Clara M.; Lundquist, Julie K.; Handschy, Mark A.

    2015-04-01

    The variability in wind-generated electricity complicates the integration of this electricity into the electrical grid. This challenge steepens as the percentage of renewably-generated electricity on the grid grows, but variability can be reduced by exploiting geographic diversity: correlations between wind farms decrease as the separation between wind farms increases. But how far is far enough to reduce variability? Grid management requires balancing production on various timescales, and so consideration of correlations reflective of those timescales can guide the appropriate spatial scales of geographic diversity grid integration. To answer ‘how far is far enough,’ we investigate the universal behavior of geographic diversity by exploring wind-speed correlations using three extensive datasets spanning continents, durations and time resolution. First, one year of five-minute wind power generation data from 29 wind farms span 1270 km across Southeastern Australia (Australian Energy Market Operator). Second, 45 years of hourly 10 m wind-speeds from 117 stations span 5000 km across Canada (National Climate Data Archive of Environment Canada). Finally, four years of five-minute wind-speeds from 14 meteorological towers span 350 km of the Northwestern US (Bonneville Power Administration). After removing diurnal cycles and seasonal trends from all datasets, we investigate dependence of correlation length on time scale by digitally high-pass filtering the data on 0.25-2000 h timescales and calculating correlations between sites for each high-pass filter cut-off. Correlations fall to zero with increasing station separation distance, but the characteristic correlation length varies with the high-pass filter applied: the higher the cut-off frequency, the smaller the station separation required to achieve de-correlation. Remarkable similarities between these three datasets reveal behavior that, if universal, could be particularly useful for grid management. For high

  18. Variability of interconnected wind plants: correlation length and its dependence on variability time scale

    SciTech Connect

    St. Martin, Clara M.; Lundquist, Julie K.; Handschy, Mark A.

    2015-04-02

    The variability in wind-generated electricity complicates the integration of this electricity into the electrical grid. This challenge steepens as the percentage of renewably-generated electricity on the grid grows, but variability can be reduced by exploiting geographic diversity: correlations between wind farms decrease as the separation between wind farms increases. However, how far is far enough to reduce variability? Grid management requires balancing production on various timescales, and so consideration of correlations reflective of those timescales can guide the appropriate spatial scales of geographic diversity grid integration. To answer 'how far is far enough,' we investigate the universal behavior of geographic diversity by exploring wind-speed correlations using three extensive datasets spanning continents, durations and time resolution. First, one year of five-minute wind power generation data from 29 wind farms span 1270 km across Southeastern Australia (Australian Energy Market Operator). Second, 45 years of hourly 10 m wind-speeds from 117 stations span 5000 km across Canada (National Climate Data Archive of Environment Canada). Finally, four years of five-minute wind-speeds from 14 meteorological towers span 350 km of the Northwestern US (Bonneville Power Administration). After removing diurnal cycles and seasonal trends from all datasets, we investigate dependence of correlation length on time scale by digitally high-pass filtering the data on 0.25–2000 h timescales and calculating correlations between sites for each high-pass filter cut-off. Correlations fall to zero with increasing station separation distance, but the characteristic correlation length varies with the high-pass filter applied: the higher the cut-off frequency, the smaller the station separation required to achieve de-correlation. Remarkable similarities between these three datasets reveal behavior that, if universal, could be particularly useful for grid management. For high

  19. Measurements of the Influence of Integral Length Scale on Stagnation Region Heat Transfer

    NASA Technical Reports Server (NTRS)

    Vanfossen, G. James; Ching, Chang Y.

    1994-01-01

    The purpose was twofold: first, to determine if a length scale existed that would cause the greatest augmentation in stagnation region heat transfer for a given turbulence intensity and second, to develop a prediction tool for stagnation heat transfer in the presence of free stream turbulence. Toward this end, a model with a circular leading edge was fabricated with heat transfer gages in the stagnation region. The model was qualified in a low turbulence wind tunnel by comparing measurements with Frossling's solution for stagnation region heat transfer in a laminar free stream. Five turbulence generating grids were fabricated; four were square mesh, biplane grids made from square bars. Each had identical mesh to bar width ratio but different bar widths. The fifth grid was an array of fine parallel wires that were perpendicular to the axis of the cylindrical leading edge. Turbulence intensity and integral length scale were measured as a function of distance from the grids. Stagnation region heat transfer was measured at various distances downstream of each grid. Data were taken at cylinder Reynolds numbers ranging from 42,000 to 193,000. Turbulence intensities were in the range 1.1 to 15.9 percent while the ratio of integral length scale to cylinder diameter ranged from 0.05 to 0.30. Stagnation region heat transfer augmentation increased with decreasing length scale. An optimum scale was not found. A correlation was developed that fit heat transfer data for the square bar grids to within +4 percent. The data from the array of wires were not predicted by the correlation; augmentation was higher for this case indicating that the degree of isotropy in the turbulent flow field has a large effect on stagnation heat transfer. The data of other researchers are also compared with the correlation.

  20. Postulates for measures of genuine multipartite correlations

    SciTech Connect

    Bennett, Charles H.; Grudka, Andrzej; Horodecki, Michal; Horodecki, Ryszard; Horodecki, Pawel

    2011-01-15

    A lot of research has been done on multipartite correlations, but the problem of satisfactorily defining genuine multipartite correlations--those not trivially reducible to lower partite correlations--remains unsolved. In this paper we propose three reasonable postulates which each measure or indicator of genuine multipartite correlations (or genuine multipartite entanglement) should satisfy. We also introduce the concept of degree of correlations, which gives partial characterization of multipartite correlations. Then, we show that covariance does not satisfy two postulates and hence it cannot be used as an indicator of genuine multipartite correlations. Finally, we propose a candidate for a measure of genuine multipartite correlations based on the work that can be drawn from a local heat bath by means of a multipartite state.

  1. Correlations between psychometric schizotypy, scan path length, fixations on the eyes and face recognition.

    PubMed

    Hills, Peter J; Eaton, Elizabeth; Pake, J Michael

    2016-01-01

    Psychometric schizotypy in the general population correlates negatively with face recognition accuracy, potentially due to deficits in inhibition, social withdrawal, or eye-movement abnormalities. We report an eye-tracking face recognition study in which participants were required to match one of two faces (target and distractor) to a cue face presented immediately before. All faces could be presented with or without paraphernalia (e.g., hats, glasses, facial hair). Results showed that paraphernalia distracted participants, and that the most distracting condition was when the cue and the distractor face had paraphernalia but the target face did not, while there was no correlation between distractibility and participants' scores on the Schizotypal Personality Questionnaire (SPQ). Schizotypy was negatively correlated with proportion of time fixating on the eyes and positively correlated with not fixating on a feature. It was negatively correlated with scan path length and this variable correlated with face recognition accuracy. These results are interpreted as schizotypal traits being associated with a restricted scan path leading to face recognition deficits. PMID:25835241

  2. Variability of interconnected wind plants: correlation length and its dependence on variability time scale

    DOE PAGESBeta

    St. Martin, Clara M.; Lundquist, Julie K.; Handschy, Mark A.

    2015-04-02

    The variability in wind-generated electricity complicates the integration of this electricity into the electrical grid. This challenge steepens as the percentage of renewably-generated electricity on the grid grows, but variability can be reduced by exploiting geographic diversity: correlations between wind farms decrease as the separation between wind farms increases. However, how far is far enough to reduce variability? Grid management requires balancing production on various timescales, and so consideration of correlations reflective of those timescales can guide the appropriate spatial scales of geographic diversity grid integration. To answer 'how far is far enough,' we investigate the universal behavior of geographic diversity by exploring wind-speed correlations using three extensive datasets spanning continents, durations and time resolution. First, one year of five-minute wind power generation data from 29 wind farms span 1270 km across Southeastern Australia (Australian Energy Market Operator). Second, 45 years of hourly 10 m wind-speeds from 117 stations span 5000 km across Canada (National Climate Data Archive of Environment Canada). Finally, four years of five-minute wind-speeds from 14 meteorological towers span 350 km of the Northwestern US (Bonneville Power Administration). After removing diurnal cycles and seasonal trends from all datasets, we investigate dependence of correlation length on time scale by digitally high-pass filtering the data on 0.25–2000 h timescales and calculating correlations between sites for each high-pass filter cut-off. Correlations fall to zero with increasing station separation distance, but the characteristic correlation length varies with the high-pass filter applied: the higher the cut-off frequency, the smaller the station separation required to achieve de-correlation. Remarkable similarities between these three datasets reveal behavior that, if universal, could be particularly useful for grid management. For high

  3. Transfer-matrix scaling from disorder-averaged correlation lengths for diluted Ising systems

    NASA Astrophysics Data System (ADS)

    de Queiroz, S. L. A.; Stinchcombe, R. B.

    1994-10-01

    A transfer-matrix-scaling technique is developed for randomly diluted systems, and applied to the site-diluted Ising model on a square lattice in two dimensions. For each allowed disorder configuration between two adjacent columns, the contribution of the respective transfer matrix to the decay of correlations is considered only as far as the ratio of its two largest eigenvalues, allowing an economical calculation of a configuration-averaged correlation length. Standard phenomenological-renormalization procedures are then used to analyze aspects of the phase boundary which are difficult to assess accurately by alternative methods. For magnetic site concentration p close to pc, the extent of exponential behavior of the Tc×p curve is clearly seen for over two decades of variation of p-pc. Close to the pure-system limit, the exactly known reduced slope is reproduced to a very good approximation, though with nonmonotonic convergence. The averaged correlation lengths are inserted into the exponent-amplitude relationship predicted by conformal invariance to hold at criticality. The resulting exponent η remains near the pure value (1/4) for all intermediate concentrations until it crosses over to the percolation value at the threshold.

  4. Scale and time dependence of serial correlations in word-length time series of written texts

    NASA Astrophysics Data System (ADS)

    Rodriguez, E.; Aguilar-Cornejo, M.; Femat, R.; Alvarez-Ramirez, J.

    2014-11-01

    This work considered the quantitative analysis of large written texts. To this end, the text was converted into a time series by taking the sequence of word lengths. The detrended fluctuation analysis (DFA) was used for characterizing long-range serial correlations of the time series. To this end, the DFA was implemented within a rolling window framework for estimating the variations of correlations, quantified in terms of the scaling exponent, strength along the text. Also, a filtering derivative was used to compute the dependence of the scaling exponent relative to the scale. The analysis was applied to three famous English-written literary narrations; namely, Alice in Wonderland (by Lewis Carrol), Dracula (by Bram Stoker) and Sense and Sensibility (by Jane Austen). The results showed that high correlations appear for scales of about 50-200 words, suggesting that at these scales the text contains the stronger coherence. The scaling exponent was not constant along the text, showing important variations with apparent cyclical behavior. An interesting coincidence between the scaling exponent variations and changes in narrative units (e.g., chapters) was found. This suggests that the scaling exponent obtained from the DFA is able to detect changes in narration structure as expressed by the usage of words of different lengths.

  5. Weak Measurements Destroy Too Much Quantum Correlation

    NASA Astrophysics Data System (ADS)

    Wu, Shao-xiong; Zhang, Jun; Yu, Chang-shui; Song, He-shan

    2016-01-01

    The quantum correlation under weak measurements is studied via skew information. For 2 × d-dimensional states, it can be given by a closed form which linearly depends on the quantum correlation [EPL. 107 (2014) 10007] determined by the strength of the weak measurement. It is found that the quantum correlation under weak measurements only captures partial quantumness of the state. In particular, the extraction of the residual quantumness by the latter measurements will inevitably destroy too much quantumness. To demonstration, the Werner state is given as an example.

  6. Significant Correlation of Species Longevity with DNA Double Strand Break-Recognition but not with Telomere Length

    PubMed Central

    Lorenzini, Antonello; Johnson, F. Brad; Oliver, Anthony; Tresini, Maria; Smith, Jasmine S.; Hdeib, Mona; Sell, Christian; Cristofalo, Vincent J.; Stamato, Thomas D.

    2009-01-01

    Summary The identification of the cellular mechanisms responsible for the wide differences in species lifespan remains one of the major unsolved problems of the biology of aging. We measured the capacity of nuclear protein to recognize DNA double strand breaks (DSB) and telomere length of skin fibroblasts derived from mammalian species that exhibit wide differences in longevity. Our results indicate DNA DSB recognition increases exponentially with longevity. Further, an analysis of the level of Ku80 protein in human, cow, and mouse suggests that Ku levels vary dramatically between species and these levels are strongly correlated with longevity. In contrast mean telomere length appears to decrease with increasing longevity of the species, although not significantly. These findings suggest that an enhanced ability to bind to DNA-ends may be important for longevity. A number of possible roles for increased levels of Ku and DNA-PKcs are discussed. PMID:19896964

  7. Donor site wound protein synthesis correlates with length of acute hospitalization in severely burned children: a pilot study

    PubMed Central

    Tuvdendorj, Demidmaa; Chinkes, David L.; Zhang, Xiao-Jun; Aarsland, Asle; Herndon, David N.

    2014-01-01

    Autografting of burn wounds results in generation of donor site wounds. Here we measured donor site wound protein Fractional Synthesis Rate (FSR) in a burn pediatric population and showed that FSR increases over time postsurgery and correlates with the length of hospital stay (LOS) normalized for total body surface area (TBSA) burn size. 3.9±1.1 days after the grafting surgery patients participated in a metabolic study consisting of continuous infusion of L-[ring-2H5]-phenylalanine and donor site wound punch biopsies. Donor site wound protein FSR was 10.4±7.5 %/day. Wound FSR demonstrated linear correlation with the time postsurgery (p < 0.05). Multiple regression analysis showed that LOS/TBSA correlated with donor site wound protein FSR and time postsurgery (p < 0.001) and the following equation describes the relationship: Estimated LOS/TBSA = (FSR - 12.95 – 1.414 × Postsurgery day)/(−17.8). This equation predicted that FSR corrected for the postsurgery day when the metabolic study was conducted accounted for 67 % of the variability (r2 = 0.673) in the LOS/TBSA. Donor site wound protein FSR correlated to LOS/TBSA of burn patients admitted to the intensive care unit. Measurement of protein deposition in regenerating donor site wound using stable isotope technique provides a quantitative measure of wound healing. PMID:20412556

  8. Topological phases and topological entropy of two-dimensional systems with finite correlation length

    SciTech Connect

    Papanikolaou, Stefanos; Fradkin, Eduardo; Raman, Kumar S.

    2007-12-01

    We elucidate the topological features of the entanglement entropy of a region in two-dimensional quantum systems in a topological phase with a finite correlation length {xi}. First, we suggest that simpler reduced quantities, related to the von Neumann entropy, could be defined to compute the topological entropy. We use our methods to compute the entanglement entropy for the ground-state wave function of a quantum eight-vertex model in its topological phase and show that a finite correlation length adds corrections of the same order as the topological entropy which come from sharp features of the boundary of the region under study. We also calculate the topological entropy for the ground state of the quantum dimer model on a triangular lattice by using a mapping to a loop model. The topological entropy of the state is determined by loop configurations with a nontrivial winding number around the region under study. Finally, we consider extensions of the Kitaev wave function, which incorporate the effects of electric and magnetic charge fluctuations, and use it to investigate the stability of the topological phase by calculating the topological entropy.

  9. Norm-based measurement of quantum correlation

    SciTech Connect

    Wu Yuchun; Guo Guangcan

    2011-06-15

    In this paper we derived a necessary and sufficient condition for classical correlated states and proposed a norm-based measurement Q of quantum correlation. Using the max norm of operators, we gave the expression of the quantum correlation measurement Q and investigated the dynamics of Q in Markovian and non-Markovian cases, respectively. Q decays exponentially and vanishes only asymptotically in the Markovian case and causes periodical death and rebirth in the non-Markovian case. In the pure state, the quantum correlation Q is always larger than the entanglement, which was different from other known measurements. In addition, we showed that locally broadcastable and broadcastable are equivalent and reproved the density of quantum correlated states.

  10. Complexity measures, emergence, and multiparticle correlations.

    PubMed

    Galla, Tobias; Gühne, Otfried

    2012-04-01

    We study correlation measures for complex systems. First, we investigate some recently proposed measures based on information geometry. We show that these measures can increase under local transformations as well as under discarding particles, thereby questioning their interpretation as a quantifier for complexity or correlations. We then propose a refined definition of these measures, investigate its properties, and discuss its numerical evaluation. As an example, we study coupled logistic maps and study the behavior of the different measures for that case. Finally, we investigate other local effects during the coarse graining of the complex system. PMID:22680558

  11. Complexity measures, emergence, and multiparticle correlations

    NASA Astrophysics Data System (ADS)

    Galla, Tobias; Gühne, Otfried

    2012-04-01

    We study correlation measures for complex systems. First, we investigate some recently proposed measures based on information geometry. We show that these measures can increase under local transformations as well as under discarding particles, thereby questioning their interpretation as a quantifier for complexity or correlations. We then propose a refined definition of these measures, investigate its properties, and discuss its numerical evaluation. As an example, we study coupled logistic maps and study the behavior of the different measures for that case. Finally, we investigate other local effects during the coarse graining of the complex system.

  12. Instrument for measuring thin-film belt lengths

    NASA Technical Reports Server (NTRS)

    Casad, T. A.; Piggott, H.; Hoffman, J. K.

    1974-01-01

    Instrument consists of base, vernier height gauge, sliding block, and balance-beam assembly with tension weight. Pulley bracket is provided with three pulley mounting holes, 4 inches apart, to accommodate widely different belt lengths. Instrument is accurate to within 0.001 inch and is suitable for commercial production.

  13. Telomere length measurement by a novel Luminex-based assay: a blinded comparison to Southern blot.

    PubMed

    Pierce, Brandon L; Jasmine, Farzana; Roy, Shantanu; Zhang, Chenan; Aviv, Abraham; Hunt, Steven C; Ahsan, Habibul; Kibriya, Muhammad G

    2016-01-01

    Telomere length (TL) is a potential biomarker of aging and age-related disease risk. We recently published a novel Luminex-based method for high-throughput, low-cost TL measurement. Here we describe a blinded comparison of the Luminex method to Southern blot, the most precise TL measurement method. Luminex and Southern blot measurements for the same 50 DNA samples were taken in two independent laboratories; each sample was measured twice, several months apart. The inter-assay CV for Luminex ranged from 5.5 to 9.1 (depending on CV estimation method), and Southern blot CV from 1.0 to 1.7. Both measures were inversely associated with age. The correlation between the repeated measurements was 0.66 for Luminex and 0.97 for Southern blot. The correlation between Southern blot and Luminex was 0.65 in round 1 and 0.75 in round 2, and the relationship showed no evidence of non-linearity. Our results demonstrate that the Luminex assay is a valid and reproducible method for high-throughput TL measurement. The Luminex assay involves no DNA amplification, which may make Luminex an attractive alternative to PCR-based TL measurement. PMID:27186324

  14. Telomere length measurement by a novel Luminex-based assay: a blinded comparison to Southern blot

    PubMed Central

    Pierce, Brandon L; Jasmine, Farzana; Roy, Shantanu; Zhang, Chenan; Aviv, Abraham; Hunt, Steven C; Ahsan, Habibul; Kibriya, Muhammad G

    2016-01-01

    Telomere length (TL) is a potential biomarker of aging and age-related disease risk. We recently published a novel Luminex-based method for high-throughput, low-cost TL measurement. Here we describe a blinded comparison of the Luminex method to Southern blot, the most precise TL measurement method. Luminex and Southern blot measurements for the same 50 DNA samples were taken in two independent laboratories; each sample was measured twice, several months apart. The inter-assay CV for Luminex ranged from 5.5 to 9.1 (depending on CV estimation method), and Southern blot CV from 1.0 to 1.7. Both measures were inversely associated with age. The correlation between the repeated measurements was 0.66 for Luminex and 0.97 for Southern blot. The correlation between Southern blot and Luminex was 0.65 in round 1 and 0.75 in round 2, and the relationship showed no evidence of non-linearity. Our results demonstrate that the Luminex assay is a valid and reproducible method for high-throughput TL measurement. The Luminex assay involves no DNA amplification, which may make Luminex an attractive alternative to PCR-based TL measurement. PMID:27186324

  15. On the measurability of quantum correlation functions

    SciTech Connect

    Lima Bernardo, Bertúlio de Azevedo, Sérgio; Rosas, Alexandre

    2015-05-15

    The concept of correlation function is widely used in classical statistical mechanics to characterize how two or more variables depend on each other. In quantum mechanics, on the other hand, there are observables that cannot be measured at the same time; the so-called incompatible observables. This prospect imposes a limitation on the definition of a quantum analog for the correlation function in terms of a sequence of measurements. Here, based on the notion of sequential weak measurements, we circumvent this limitation by introducing a framework to measure general quantum correlation functions, in principle, independently of the state of the system and the operators involved. To illustrate, we propose an experimental configuration to obtain explicitly the quantum correlation function between two Pauli operators, in which the input state is an arbitrary mixed qubit state encoded on the polarization of photons.

  16. Heritabilities and genetic correlations of body weights and feather length in growing Muscovy selected in Taiwan.

    PubMed

    Hu, Y H; Poivey, J P; Rouvier, R; Wang, C T; Tai, C

    1999-12-01

    1. Heritabilities and genetic correlations in the base population of a closed strain of Muscovy duck, moderately selected for body weight at 10 weeks of age, have been estimated from the data of 9 successive generations for the following traits: male and female body weight at 10 and 18 weeks of age (BW10m, BW18m, BW10f, BW18f) and length of the 8th primary feather at 10 weeks of age (F110m, F110f). 2. Multivariate REML with an animal model was used, pooling data from the 9 generations (3283 and 3289 male and female offspring respectively). The same trait expressed in male and female was considered as 2 different traits. 3. The 8th primary feather was longer in females than in males by 6% to 22% at 10 weeks of age. Body weight was heavier in males than in females by 42% to 58% at 10 weeks of age and by 57% to 75% at 18 weeks of age. 3. The heritability estimates for body weight traits showed moderate values, being a little higher for females than for males at the same age, increasing with age from h2=0.24 at BW10m to h2=0.43 at BW18f. 4. The heritability estimates for feather length showed that a greater response would be obtained in selection for male feather length (h2=0.37) than for female length (h2=0.14). Both have high genetic correlations with body weight so they could be indirectly improved. 5. Heritabilities of the difference in body weights between males and females at 10 weeks (h2=0.07) and 18 weeks of age (h2=0.10) were small, as well as for feather length (h2=0.10). It would probably be difficult to modify sexual dimorphism in body weight through selection. 6. Genetic correlations between BW10m, BW18m and BW10f, BW18f were respectively r(g)=0.77 and r(g)=0.80. They were larger for body weight at the same ages between males and females, r(g)=0.90 (r(g)=0.88 between F110m and F110f). Body weight in males and females at the same age should be better considered as 2 different traits in a selection programme. 7. The cumulated predicted genetic gains

  17. Knemometry in childhood: accuracy and standardization of a new technique of lower leg length measurement.

    PubMed

    Hermanussen, M; Geiger-Benoit, K; Burmeister, J; Sippell, W G

    1988-01-01

    Recently, a new anthropometric method of accurate lower leg length measurement (knemometry) was introduced. The present study was performed to investigate rigorously its strengths and weaknesses for auxological purposes, and to promote a standardized method of use. The data are based on 6 x 2200 single estimations of the lower leg length in 90 children of both sexes with normal, tall or short stature aged between 2.4 and 17.1 years. The overall technical error of this measurement was found to be 0.16 mm, which is reduced to 0.13 mm if the first estimation within each series of six is ignored. The following sources of systematic error could be detected: intra-daily variation, dependency on physical pressure put on or removed from the leg, vigorous physical activity prior to the measuring procedure, and a slow but significant correlation between day-to-day variation of lower leg length and body weight (r = 0.299, b = 0.372 mm/kg). There was no covariation with atmospheric parameters such as outside temperature, barometric pressure and others. After elimination of a linear trend from the individual growth curves, there was a remaining day-to-day variation of SD = 0.697 mm. This represents real changes of lower leg length and cannot be explained by the technical error of measurement which contributes to less than 10% of the total variation. Some of this day-to-day variation may be explained by non-linearity of growth. Knemometry appears to be a robust and precise new tool for the investigation of short term kinetics of longitudinal growth. Proposals for a standardized use of this technique are given. PMID:3348587

  18. Measuring and modeling correlations in multiplex networks.

    PubMed

    Nicosia, Vincenzo; Latora, Vito

    2015-09-01

    The interactions among the elementary components of many complex systems can be qualitatively different. Such systems are therefore naturally described in terms of multiplex or multilayer networks, i.e., networks where each layer stands for a different type of interaction between the same set of nodes. There is today a growing interest in understanding when and why a description in terms of a multiplex network is necessary and more informative than a single-layer projection. Here we contribute to this debate by presenting a comprehensive study of correlations in multiplex networks. Correlations in node properties, especially degree-degree correlations, have been thoroughly studied in single-layer networks. Here we extend this idea to investigate and characterize correlations between the different layers of a multiplex network. Such correlations are intrinsically multiplex, and we first study them empirically by constructing and analyzing several multiplex networks from the real world. In particular, we introduce various measures to characterize correlations in the activity of the nodes and in their degree at the different layers and between activities and degrees. We show that real-world networks exhibit indeed nontrivial multiplex correlations. For instance, we find cases where two layers of the same multiplex network are positively correlated in terms of node degrees, while other two layers are negatively correlated. We then focus on constructing synthetic multiplex networks, proposing a series of models to reproduce the correlations observed empirically and/or to assess their relevance. PMID:26465526

  19. Measuring and modeling correlations in multiplex networks

    NASA Astrophysics Data System (ADS)

    Nicosia, Vincenzo; Latora, Vito

    2015-09-01

    The interactions among the elementary components of many complex systems can be qualitatively different. Such systems are therefore naturally described in terms of multiplex or multilayer networks, i.e., networks where each layer stands for a different type of interaction between the same set of nodes. There is today a growing interest in understanding when and why a description in terms of a multiplex network is necessary and more informative than a single-layer projection. Here we contribute to this debate by presenting a comprehensive study of correlations in multiplex networks. Correlations in node properties, especially degree-degree correlations, have been thoroughly studied in single-layer networks. Here we extend this idea to investigate and characterize correlations between the different layers of a multiplex network. Such correlations are intrinsically multiplex, and we first study them empirically by constructing and analyzing several multiplex networks from the real world. In particular, we introduce various measures to characterize correlations in the activity of the nodes and in their degree at the different layers and between activities and degrees. We show that real-world networks exhibit indeed nontrivial multiplex correlations. For instance, we find cases where two layers of the same multiplex network are positively correlated in terms of node degrees, while other two layers are negatively correlated. We then focus on constructing synthetic multiplex networks, proposing a series of models to reproduce the correlations observed empirically and/or to assess their relevance.

  20. Single-shot electron bunch length measurements using a spatial electro-optical autocorrelation interferometer

    NASA Astrophysics Data System (ADS)

    Sütterlin, Daniel; Erni, Daniel; Schlott, Volker; Sigg, Hans; Jäckel, Heinz; Murk, Axel

    2010-10-01

    A spatial, electro-optical autocorrelation (EOA) interferometer using the vertically polarized lobes of coherent transition radiation (CTR) has been developed as a single-shot electron bunch length monitor at an optical beam port downstream the 100 MeV preinjector LINAC of the Swiss Light Source. This EOA monitor combines the advantages of step-scan interferometers (high temporal resolution) [D. Mihalcea et al., Phys. Rev. ST Accel. Beams 9, 082801 (2006) and T. Takahashi and K. Takami, Infrared Phys. Technol. 51, 363 (2008)] and terahertz-gating technologies [U. Schmidhammer et al., Appl. Phys. B: Lasers Opt. 94, 95 (2009) and B. Steffen et al., Phys. Rev. ST Accel. Beams 12, 032802 (2009)] (fast response), providing the possibility to tune the accelerator with an online bunch length diagnostics. While a proof of principle of the spatial interferometer was achieved by step-scan measurements with far-infrared detectors, the single-shot capability of the monitor has been demonstrated by electro-optical correlation of the spatial CTR interference pattern with fairly long (500 ps) neodymium-doped yttrium aluminum garnet (Nd:YAG) laser pulses in a ZnTe crystal. In single-shot operation, variations of the bunch length between 1.5 and 4 ps due to different phase settings of the LINAC bunching cavities have been measured with subpicosecond time resolution.

  1. Single-shot electron bunch length measurements using a spatial electro-optical autocorrelation interferometer

    SciTech Connect

    Suetterlin, Daniel; Erni, Daniel; Schlott, Volker; Sigg, Hans; Jaeckel, Heinz; Murk, Axel

    2010-10-15

    A spatial, electro-optical autocorrelation (EOA) interferometer using the vertically polarized lobes of coherent transition radiation (CTR) has been developed as a single-shot electron bunch length monitor at an optical beam port downstream the 100 MeV preinjector LINAC of the Swiss Light Source. This EOA monitor combines the advantages of step-scan interferometers (high temporal resolution) [D. Mihalcea et al., Phys. Rev. ST Accel. Beams 9, 082801 (2006) and T. Takahashi and K. Takami, Infrared Phys. Technol. 51, 363 (2008)] and terahertz-gating technologies [U. Schmidhammer et al., Appl. Phys. B: Lasers Opt. 94, 95 (2009) and B. Steffen et al., Phys. Rev. ST Accel. Beams 12, 032802 (2009)] (fast response), providing the possibility to tune the accelerator with an online bunch length diagnostics. While a proof of principle of the spatial interferometer was achieved by step-scan measurements with far-infrared detectors, the single-shot capability of the monitor has been demonstrated by electro-optical correlation of the spatial CTR interference pattern with fairly long (500 ps) neodymium-doped yttrium aluminum garnet (Nd:YAG) laser pulses in a ZnTe crystal. In single-shot operation, variations of the bunch length between 1.5 and 4 ps due to different phase settings of the LINAC bunching cavities have been measured with subpicosecond time resolution.

  2. Noise probes of underlying static correlation lengths in the superconducting peak effect

    SciTech Connect

    Rabin, M.W.; Merithew, R.D.; Weissman, M.B.; Higgins, M.J.; Bhattacharya, S.

    1998-01-01

    The sensitivity of low-frequency noise to ac magnetic-field perturbations is explored in the plastic flow regime near the {open_quotes}peak effect{close_quotes} in the clean type-II superconductor NbSe{sub 2}. Very small ac magnetic fields (on the order of 1 Oe in a dc field of about 20000 Oe) substantially reduce the low-frequency spectral density by inducing rapid switching among metastable configurations present in the pinned state. This sensitivity to ac fields shrinks rapidly as H increases in the peak-effect regime, indicating reduced static correlation lengths as the peak is approached. {copyright} {ital 1998} {ital The American Physical Society}

  3. Fitness correlates of spur length and spur asymmetry in male wild turkeys.

    PubMed

    Badyaev, A V; Etges, W J; Faust, J D; Martin, T E

    1998-11-01

    Tarsal spurs play an important role in intrasexual competition for females among male wild turkeys (Meleagris gallopavo). Thus variation in spur development may have important fitness consequences. Fitness correlates of spur development were studied in a free-living population of wild turkeys and it was found that heavier males and males with longer beards had longer spurs. Males that had longer spurs spent more time on display areas during the breeding season and less time moving among these areas compared to males with shorter spurs, independently of their body mass. Otherwise ideally symmetrical spurs showed fluctuating asymmetry between left and right tarsi, the degree of absolute asymmetry decreased with spur length in adults, but not in subadults, and males that survived at least one winter had more symmetrical spurs compared to males that did not. We conclude that if the ability to produce symmetrical spurs has a genetic basis, then spur length and spur asymmetry could reliably indicate individual quality and that these traits are under directional selection for increased size and symmetry in wild turkeys. PMID:26412365

  4. Error analysis and modeling for the time grating length measurement system

    NASA Astrophysics Data System (ADS)

    Gao, Zhonghua; Fen, Jiqin; Zheng, Fangyan; Chen, Ziran; Peng, Donglin; Liu, Xiaokang

    2013-10-01

    Through analyzing errors of the length measurement system in which a linear time grating was the principal measuring component, we found that the study on the error law was very important to reduce system errors and optimize the system structure. Mainly error sources in the length measuring system, including the time grating sensor, slide way, and cantilever, were studied; and therefore total errors were obtained. Meanwhile we erected the mathematic model of errors of the length measurement system. Using the error model, we calibrated system errors being in the length measurement system. Also, we developed a set of experimental devices in which a laser interferometer was used to calibrate the length measurement system errors. After error calibrating, the accuracy of the measurement system was improved from original 36um/m to 14um/m. The fact that experiment results are consistent with the simulation results shows that the error mathematic model is suitable for the length measuring system.

  5. Hepcidin and Iron Metabolism in Pregnancy: Correlation with Smoking and Birth Weight and Length.

    PubMed

    Chełchowska, Magdalena; Ambroszkiewicz, Jadwiga; Gajewska, Joanna; Jabłońska-Głąb, Ewa; Maciejewski, Tomasz M; Ołtarzewski, Mariusz

    2016-09-01

    To estimate the effect of tobacco smoking on iron homeostasis and the possible association between hepcidin and the neonatal birth weight and length, concentrations of serum hepcidin and selected iron markers were measured in 81 healthy pregnant women (41 smokers and 40 nonsmokers). The smoking mothers had significantly lower concentrations of serum hepcidin (p < 0.001), iron (p < 0.001), and hemoglobin (p < 0.05), but higher erythropoietin (p < 0.05) levels compared with non-smoking pregnant women. Logistic regression analysis showed the highest negative impact of the number of cigarettes smoked per day (β = -0.46; p < 0.01) and positive impact of ferritin level (β = 0.47; p < 0.001) on serum hepcidin concentration. The birth weight and the body length of smoking mothers' infants were significantly lower than in tobacco abstinent group (p < 0.001). In multiple regression analysis, birth body weight (β = 0.56; p < 0.001) and length (β = 0.50; p < 0.001) were significantly related to maternal hepcidin values. Tobacco smoking affected hepcidin level in serum of pregnant women in a dose-dependent manner. Low concentrations of iron and hemoglobin in maternal serum coexisting with high level of erythropoietin suggest that smoking could lead to subclinical iron deficiency and chronic hypoxia not only in mothers but also in fetus. Low serum hepcidin concentration in smoking pregnant women might be associated with lower fetal birth weight and length. PMID:26785641

  6. In vivo measurements of biceps brachii and triceps brachii fascicle lengths using extended field-of-view ultrasound.

    PubMed

    Nelson, Christa M; Dewald, Julius P A; Murray, Wendy M

    2016-06-14

    Muscle fascicle lengths are commonly measured in vivo using static 2D ultrasound. However, static ultrasound is best suited for muscles with shorter, pennate fascicles, in which entire fascicles can be viewed in one static image. An informal review of data from cadaver dissections suggests that over 60% of muscles in the upper and lower limbs have optimal lengths longer than the field-of-view of standard ultrasound transducers. Extended field-of-view ultrasound (EFOV) has been validated for measurement of fascicle lengths, but has yet to be implemented in the upper extremity in humans. In this study, EFOV ultrasound was used to measure the lengths of fascicles sampled from the anterior portion of the biceps brachii (long head) and the distal half of the triceps brachii (lateral head). Data were collected from both limbs of eleven healthy subjects in three elbow postures under passive conditions. Image analysis was completed via Image J. Fascicle length measurements were highly reliable, with intra-class correlations ranging from .92 to .95 for biceps and .81-.92 for triceps (p<.001). Systematic, significant differences in measured lengths, consistent with muscle function, were observed between elbow positions. In vivo measurements for both muscles in this study were within the range of cadaver data. This work establishes the feasibility and reliability of EFOV ultrasound for measurement of the long fascicles of muscles in the upper limb. PMID:27083062

  7. Correlation of interannual length-of-day variation with El Nino/Southern Oscillation, 1972-1986

    NASA Technical Reports Server (NTRS)

    Chao, B. Fong

    1988-01-01

    Correlation between interannual length-of-day (LOD) changes and an index representation of El Nino/Southern Oscillation (ENSO) for the period of 1972-1986 was examined in two ways: as the cross-correlation function in the time domain and as the complex coherence spectrum in the frequency domain. The ENSO representation was derived from barometric measurements from the Tahiti and Darwin, Australia, meteorological stations, as the difference of the sea-level pressure between the two locations. The cross correlation between this ENSO representation and LOD variation on the interannual time scale was found to have a maximum value of 0.68 and the LOD phase lag of 2 months, indicating that most of the interannual LOD variation is caused by ENSO, and that the transfer of ENSO's axial angular momentum to the solid earth lags behind the Tahiti-Darwin pressure variation by about 2 months. The corresponding coherence spectrum showed minimum correlation around biennial periods, indicating an influence of the stratospheric quasi-biennial oscillation on LOD variations.

  8. Understanding the amplitudes of noise correlation measurements

    USGS Publications Warehouse

    Tsai, Victor C.

    2011-01-01

    Cross correlation of ambient seismic noise is known to result in time series from which station-station travel-time measurements can be made. Part of the reason that these cross-correlation travel-time measurements are reliable is that there exists a theoretical framework that quantifies how these travel times depend on the features of the ambient noise. However, corresponding theoretical results do not currently exist to describe how the amplitudes of the cross correlation depend on such features. For example, currently it is not possible to take a given distribution of noise sources and calculate the cross correlation amplitudes one would expect from such a distribution. Here, we provide a ray-theoretical framework for calculating cross correlations. This framework differs from previous work in that it explicitly accounts for attenuation as well as the spatial distribution of sources and therefore can address the issue of quantifying amplitudes in noise correlation measurements. After introducing the general framework, we apply it to two specific problems. First, we show that we can quantify the amplitudes of coherency measurements, and find that the decay of coherency with station-station spacing depends crucially on the distribution of noise sources. We suggest that researchers interested in performing attenuation measurements from noise coherency should first determine how the dominant sources of noise are distributed. Second, we show that we can quantify the signal-to-noise ratio of noise correlations more precisely than previous work, and that these signal-to-noise ratios can be estimated for given situations prior to the deployment of seismometers. It is expected that there are applications of the theoretical framework beyond the two specific cases considered, but these applications await future work.

  9. Correlation Length Scales of Isotopic Variations Along Mid-Ocean Ridges and Upper Mantle Dynamics

    NASA Astrophysics Data System (ADS)

    Graham, D. W.; Spera, F. J.

    2003-12-01

    How isotopic variations in basalts erupted at the Earth's surface are linked to convective mixing in the underlying mantle is a central problem in geodynamics. The objective of this study is to quantify the length scales of upper mantle heterogeneity through spatial statistical analysis of MORB. We define a characteristic length scale, the scale of segregation L, computed from the spatial self-correlations for 3He/4He, 87Sr/86Sr, 143Nd/144Nd and 206,207,208Pb/204Pb in "zero age" lavas from mid-ocean ridges. Our working hypothesis is that small scale convection in the upper mantle controls dispersion of geochemical tracers. Differences in L between ocean basins may then be quantitatively related to unsteadiness in this convection, due to thickening of the lithosphere, plume impingement, or lateral temperature/compositional differences between continental and oceanic lithosphere induced by batholith formation. The correlation coefficient R, and the separation distance r, are calculated for every i,j pair of points. Ri,j is given by the product of the deviations in isotope composition from the population mean, normalized to the population variance, and R(r) is computed as an ensemble average. The total number of point pairs (N) for n sample locations is given by N=n(n-1)/2. For the global MORB data set (n=1265 and 735 for Sr and He, respectively), N exceeds 105 (799480 and 269745, respectively). A value of R(r) close to 1 indicates that an isotope ratio above (or below) the population average is likely to be associated with an above (or below) average value at a distance r away. A value of R(r) close to zero implies a random relationship, and a value close to -1 implies an anti-correlation. R(r) approaches unity at small r by definition, as points close together are from the same "clump" of mantle. The value of r at which R first goes to zero is denoted as r*. On a diagram of R(r) vs. r (the correlogram), the integral of R(r) from r=0 to r=r* is the scale of

  10. Automated path length and M{sub 56} measurements at Jefferson Lab

    SciTech Connect

    Hardy, D.; Tang, J.; Legg, R.

    1997-08-01

    Accurate measurement of path length and path length changes versus momentum (M{sub 56}) are critical for maintaining minimum beam energy spread in the CEBAF (Continuous Electron Beam Accelerator Facility) accelerator at the Thomas Jefferson National Accelerator Facility (Jefferson Lab). The relative path length for each circuit of the beam (1256m) must be equal within 1.5 degrees of 1497 MHz RF phase. A relative path length measurement is made by measuring the relative phases of RF signals from a cavity that is separately excited for each pass of a 4.2 {mu}s pulsed beam. This method distinguishes the path length to less than 0.5 path length error. The development of a VME based automated measurement system for path length and M{sub 56} has contributed to faster machine setup time and has the potential for use as a feedback parameter for automated control.

  11. A Comparison of the Use of Radar Images and Neutron Probe Data to Determine the Horizontal Correlation Length of Water Content

    SciTech Connect

    Knight, Rosemary J.; Irving, James D.; Tercier, Paulette; Freeman, Eugene J.; Murray, Christopher J.; Rockhold, Mark L.

    2007-11-08

    Surface-based ground-penetrating radar data were collected at the Hanford Site in Washington, U.S.A. to assess the use of radar reflection images as a means of quantifying the spatial variability of subsurface water content. Available at the selected test site were two sets of water content data derived from neutron probe measurements that had been made to a depth of ~18 m in 32 wells. The comparison of probe-derived water content data, synthetic radar data, and the acquired radar data indicated a good correspondence between the changes in probe-derived water content and the location of reflections in the radar data. Geostatistical analysis was conducted on the two sets of probe-derived water content values and the amplitudes of the reflections in the radar reflection image to determine the horizontal correlation length of water content. The experimental semivariograms for the water content data were fit with a single exponential model with a correlation length of 10 m. The semivariogram for the radar data was fit with a nested structure containing a dominant long-range structure with a correlation length of 14 m, and a smaller-scale structure with a correlation length of 0.3 m. Quantifying the scale triplet – the spacing, extent, and support – for the two forms of measurement provided a framework for comparing and assessing the derived correlation structures.

  12. Eddy Correlation Flux Measurement System (ECOR) Handbook

    SciTech Connect

    Cook, DR

    2011-01-31

    The eddy correlation (ECOR) flux measurement system provides in situ, half-hour measurements of the surface turbulent fluxes of momentum, sensible heat, latent heat, and carbon dioxide (CO2) (and methane at one Southern Great Plains extended facility (SGP EF) and the North Slope of Alaska Central Facility (NSA CF). The fluxes are obtained with the eddy covariance technique, which involves correlation of the vertical wind component with the horizontal wind component, the air temperature, the water vapor density, and the CO2 concentration.

  13. Cerebrospinal Fluid Hypocretin-1 (Orexin-A) Level Fluctuates with Season and Correlates with Day Length.

    PubMed

    Boddum, Kim; Hansen, Mathias Hvidtfelt; Jennum, Poul Jørgen; Kornum, Birgitte Rahbek

    2016-01-01

    The hypocretin/orexin neuropeptides (hcrt) are key players in the control of sleep and wakefulness evidenced by the fact that lack of hcrt leads to the sleep disorder Narcolepsy Type 1. Sleep disturbances are common in mood disorders, and hcrt has been suggested to be poorly regulated in depressed subjects. To study seasonal variation in hcrt levels, we obtained data on hcrt-1 levels in the cerebrospinal fluid (CSF) from 227 human individuals evaluated for central hypersomnias at a Danish sleep center. The samples were taken over a 4 year timespan, and obtained in the morning hours, thus avoiding impact of the diurnal hcrt variation. Hcrt-1 concentration was determined in a standardized radioimmunoassay. Using biometric data and sleep parameters, a multivariate regression analysis was performed. We found that the average monthly CSF hcrt-1 levels varied significantly across the seasons following a sine wave with its peak in the summer (June-July). The amplitude was 19.9 pg hcrt/mL [12.8-26.9] corresponding to a 10.6% increase in midsummer compared to winter. Factors found to significantly predict the hcrt-1 values were day length, presence of snow, and proximity to the Christmas holiday season. The hcrt-1 values from January were much higher than predicted from the model, suggestive of additional factors influencing the CSF hcrt-1 levels such as social interaction. This study provides evidence that human CSF hcrt-1 levels vary with season, correlating with day length. This finding could have implications for the understanding of winter tiredness, fatigue, and seasonal affective disorder. This is the first time a seasonal variation of hcrt-1 levels has been shown, demonstrating that the hcrt system is, like other neurotransmitter systems, subjected to long term modulation. PMID:27008404

  14. Cerebrospinal Fluid Hypocretin-1 (Orexin-A) Level Fluctuates with Season and Correlates with Day Length

    PubMed Central

    Boddum, Kim; Hansen, Mathias Hvidtfelt; Jennum, Poul Jørgen; Kornum, Birgitte Rahbek

    2016-01-01

    The hypocretin/orexin neuropeptides (hcrt) are key players in the control of sleep and wakefulness evidenced by the fact that lack of hcrt leads to the sleep disorder Narcolepsy Type 1. Sleep disturbances are common in mood disorders, and hcrt has been suggested to be poorly regulated in depressed subjects. To study seasonal variation in hcrt levels, we obtained data on hcrt-1 levels in the cerebrospinal fluid (CSF) from 227 human individuals evaluated for central hypersomnias at a Danish sleep center. The samples were taken over a 4 year timespan, and obtained in the morning hours, thus avoiding impact of the diurnal hcrt variation. Hcrt-1 concentration was determined in a standardized radioimmunoassay. Using biometric data and sleep parameters, a multivariate regression analysis was performed. We found that the average monthly CSF hcrt-1 levels varied significantly across the seasons following a sine wave with its peak in the summer (June—July). The amplitude was 19.9 pg hcrt/mL [12.8–26.9] corresponding to a 10.6% increase in midsummer compared to winter. Factors found to significantly predict the hcrt-1 values were day length, presence of snow, and proximity to the Christmas holiday season. The hcrt-1 values from January were much higher than predicted from the model, suggestive of additional factors influencing the CSF hcrt-1 levels such as social interaction. This study provides evidence that human CSF hcrt-1 levels vary with season, correlating with day length. This finding could have implications for the understanding of winter tiredness, fatigue, and seasonal affective disorder. This is the first time a seasonal variation of hcrt-1 levels has been shown, demonstrating that the hcrt system is, like other neurotransmitter systems, subjected to long term modulation. PMID:27008404

  15. Correlates of implicit cognitive line length representation in two-dimensional space.

    PubMed

    Doty, Richard L; Koti, Ajay; O'Hara, Thomas A; Landy, Jeffrey; Shin, Christina; Silas, Jonathan

    2014-10-01

    Twenty-eight sex- and age-matched participants, half dextrals and half sinstrals, were instructed to move a pen-sized planometer three inches (7.6 cm) while blindfolded. Under separate trials, movements were made at four angles, towards and away from the body, and at two distances from the body (30 cm, 53 cm). Half were made with the right hand and half with the left hand. Line estimates increased in length across blocks of trials in a linear fashion and progressively overestimated the three-inch imagined criterion. Lines made moving towards the body were longer than those made moving away from the body, implying an egocentric frame of reference in making the estimates. Line estimates made at an oblique angle differed significantly from estimates made at other angles. No influences of sex, handedness, or the hand used in making the estimates were observed. The findings suggest that motoric estimates of line lengths made without visual cues-a unique measure of an implicit cognitive concept-are significantly altered by temporal and spatial factors, but not by sex or hemispheric laterality. PMID:25244556

  16. On the saturation of the refractive index structure function. II - Influence of the correlation length on astronomical 'seeing'

    NASA Technical Reports Server (NTRS)

    Venkatakrishnan, P.

    1987-01-01

    A physical length scale in the wavefront corresponding to the parameter (r sub 0) characterizing the loss in detail in a long exposure image is identified, and the influence of the correlation scale of turbulence as r sub 0 approaches this scale is shown. Allowing for the effect of 2-point correlations in the fluctuations of the refractive index, Venkatakrishnan and Chatterjee (1987) proposed a modified law for the phase structure function. It is suggested that the departure of the phase structure function from the 5/3 power law for length scales in the wavefront approaching the correlation scale of turbulence may lead to better 'seeing' at longer wavelengths.

  17. Generating nonclassical correlations without fully aligning measurements

    SciTech Connect

    Wallman, Joel J.; Bartlett, Stephen D.; Liang, Yeong-Cherng

    2011-02-15

    We investigate the scenario where spatially separated parties perform measurements in randomly chosen bases on an N-partite Greenberger-Horne-Zeilinger state. We show that without any alignment of the measurements, the observers will obtain correlations that violate a Bell inequality with a probability that rapidly approaches 1 as N increases and that this probability is robust against noise. We also prove that restricting these randomly chosen measurements to a plane perpendicular to a common direction will always generate correlations that violate some Bell inequality. Specifically, if each observer chooses their two measurements to be locally orthogonal, then the N observers will violate one of two Bell inequalities by an amount that increases exponentially with N. These results are also robust against noise and perturbations of each observer's reference direction from the common direction.

  18. Computer Anxiety: Definition, Measurement, and Correlates.

    ERIC Educational Resources Information Center

    Cambre, Marjorie A.; Cook, Desmond L.

    This review examines the definition, measurement, and correlates of computer anxiety as provided in available research. The concept of computer anxiety reflects an anxiety state, rather than an anxiety trait, thus rendering it susceptible to change over time. Computer anxiety is similar in nature to math anxiety and test anxiety. Two approaches to…

  19. PHENIX Measurements of Correlations at RHIC

    NASA Astrophysics Data System (ADS)

    Taranenko, Arkadiy

    2016-01-01

    Relativistic heavy-ion collisions provide a unique opportunity to study the expansion dynamics and the transport properties of the produced strongly interacting quark gluon plasma (QGP). This article reviews the recent soft physics results obtained via correlation measurements from the PHENIX experiment at RHIC: space-time extent of the pion emission source and azimuthal anisotropy of the particle production.

  20. Quantum Correlations and the Measurement Problem

    NASA Astrophysics Data System (ADS)

    Bub, Jeffrey

    2014-10-01

    The transition from classical to quantum mechanics rests on the recognition that the structure of information is not what we thought it was: there are operational, i.e., phenomenal, probabilistic correlations that lie outside the polytope of local correlations. Such correlations cannot be simulated with classical resources, which generate classical correlations represented by the points in a simplex, where the vertices of the simplex represent joint deterministic states that are the common causes of the correlations. The `no go' hidden variable theorems tell us that we can't shoe-horn phenomenal correlations outside the local polytope into a classical simplex by supposing that something has been left out of the story. The replacement of the classical simplex by the quantum convex set as the structure representing probabilistic correlations is the analogue for quantum mechanics of the replacement of Newton's Euclidean space and time by Minkowski spacetime in special relativity. The nonclassical features of quantum mechanics, including the irreducible information loss on measurement, are generic features of correlations that lie outside the classical simplex. This paper is an elaboration of these ideas, which have their source in work by Pitowsky (J. Math. Phys. 27:1556, 1986; Math. Program. 50:395, 1991; Phys. Rev. A 77:062109, 2008), Garg and Mermin (Found. Phys. 14:1-39, 1984), Barrett (Phys. Rev. A 75:032304, 2007; Phys. Rev. A 7:022101, 2005) and others, e.g., Brunner et al. (arXiv:1303.2849, 2013), but the literature goes back to Boole (An Investigation of the Laws of Thought, Dover, New York, 1951). The final section looks at the measurement problem of quantum mechanics in this context. A large part of the problem is removed by seeing that the inconsistency in reconciling the entangled state at the end of a quantum measurement process with the definiteness of the macroscopic pointer reading and the definiteness of the correlated value of the measured micro

  1. Precise estimate of correlation length exponents from simple real-space renormalization group analysis

    NASA Astrophysics Data System (ADS)

    Kubica, Aleksander; Yoshida, Beni

    2014-03-01

    We invent a novel real-space renormalization group (RG) scheme which accurately estimates correlation length exponents ν near criticality of quantum Ising and clock models in higher dimensions. The method, based on a recent proposal by Miyazaki et al., Phys. Rev. E 83, 051103 (2011), is remarkably simple (often analytical), grouping only a few spins into a block spin so that renormalized Hamiltonian has a closed form. A previous difficulty of spatial anisotropy and unwanted terms arising in higher-dimensional RG schemes is avoided by incorporating rotational invariance and internal Zq symmetries of the Hamiltonian. By applying this scheme to (2+1)-dim Ising model on a triangular lattice, we obtained ν = 0 . 6300 which is within statistical error of the current best Monte-Carlo result and ϕ4 theory estimation with seven-loop corrections. We also apply the scheme to higher-dimensional clock (Potts) models for which ordinary Monte-Carlo methods are not efficient due to suppression of quantum fluctuation in first-order phase transition.

  2. Correlation between CAG repeat length and clinical features in Machado-Joseph disease

    SciTech Connect

    Maciel, P.; Gaspar, C.; Silveira, I.

    1995-07-01

    Machado-Joseph disease (MJD) is associated with the expansion of a CAG trinucleotide repeat in a novel gene on 14q32.1. We confirmed the presence of this expansion in 156 MJD patients from 33 families of different geographic origins: 15 Portuguese Azorean, 2 Brazilian, and 16 North American of Portuguese Azorean descent. Normal chromosomes contain between 12 and 37 CAG repeats in the MJD gene, whereas MJD gene carriers have alleles within the expanded range of 62-84 CAG units. The distribution of expanded alleles and the gap between normal and expanded allele sizes is either inconsistent with a premutation hypothesis or most (if not all) of the alleles we studied descend from a common ancestor. There is a strong correlation between the expanded repeat size and the age at onset of the disease as well as the clinical presentation. There is mild instability of the CAG tract length with transmission of the expanded alleles; both increase and decrease in size between parents and progeny occur, with larger variations in male than in female transmissions. Together, these effects can partly explain the variability of age at onset and of phenotypic features in MJD; however, other modifying factors must exist. 37 refs., 6 figs.

  3. Correlation between CAG Repeat Length and Clinical Features in Machado-Joseph Disease

    PubMed Central

    Maciel, Patrícia; Gaspar, Claudia; DeStefano, Anita L.; Silveira, Isabel; Coutinho, Paula; Radvany, João; Dawson, David M.; Sudarsky, Lewis; Guimarães, João; Loureiro, Jose E. L.; Nezarati, Marjan M.; Corwin, Lee I.; Lopes-Cendes, Iscia; Rooke, Karen; Rosenberg, Roger; MacLeod, Patrick; Farrer, Lindsay A.; Sequeiros, Jorge; Rouleau, Guy A.

    1995-01-01

    Machado-Joseph disease (MJD) is associated with the expansion of a CAG trinucleotide repeat in a novel gene on 14q32.1. We confirmed the presence of this expansion in 156 MJD patients from 33 families of different geographic origins: 15 Portuguese Azorean, 2 Brazilian, and 16 North American of Portuguese Azorean descent. Normal chromosomes contain between 12 and 37 CAG repeats in the MJD gene, whereas MJD gene carriers have alleles within the expanded range of 62–84 CAG units. The distribution of expanded alleles and the gap between normal and expanded allele sizes is either inconsistent with a premutation hypothesis or most (if not all) of the alleles we studied descend from a common ancestor. There is a strong correlation between the expanded repeat size and the age at onset of the disease as well as the clinical presentation. There is mild instability of the CAG tract length with transmission of the expanded alleles; both increase and decrease in size between parents and progeny occur, with larger variations in male than in female transmissions. Together, these effects can partly explain the variability of age at onset and of phenotypic features in MJD; however, other modifying factors must exist. ImagesFigure 3 PMID:7611296

  4. Extinction measurement with open-path cavity ring-down technique of variable cavity length.

    PubMed

    Cui, Hao; Li, Bincheng; Han, Yanling; Wang, Jing; Gao, Chunming; Wang, Yafei

    2016-06-13

    Open-path cavity ring down (OPCRD) technique with variable cavity length was developed to measure optical extinction including scattering and absorption of air in laboratory environment at 635 nm wavelength. By moving the rear cavity mirror of the ring-down cavity to change cavity length, ring-down time with different cavity lengths was experimentally obtained and the dependence of total cavity loss on cavity length was determined. The extinction coefficient of air was determined by the slope of linear dependence of total cavity loss on cavity length. The extinction coefficients of air with different particle concentrations at 635 nm wavelength were measured to be from 10.46 to 84.19 Mm-1 (ppm/m) in a normal laboratory environment. This variable-cavity-length OPCRD technique can be used for absolute extinction measurement and real-time environmental monitoring without closed-path sample cells and background measurements. PMID:27410351

  5. Measurement and analysis of sarcomere length in rat cardiomyocytes in situ and in vitro

    PubMed Central

    Camelliti, P.; Bollensdorff, C.; Stuckey, D. J.; Picton, G.; Burton, R. A. B.; Clarke, K.; Kohl, P.

    2010-01-01

    Sarcomere length (SL) is an important determinant and indicator of cardiac mechanical function; however, techniques for measuring SL in living, intact tissue are limited. Here, we present a technique that uses two-photon microscopy to directly image striations of living cells in cardioplegic conditions, both in situ (Langendorff-perfused rat hearts and ventricular tissue slices, stained with the fluorescent marker di-4-ANEPPS) and in vitro (acutely isolated rat ventricular myocytes). Software was developed to extract SL from two-photon fluorescence image sets while accounting for measurement errors associated with motion artifact in raster-scanned images and uncertainty of the cell angle relative to the imaging plane. Monte-Carlo simulations were used to guide analysis of SL measurements by determining error bounds as a function of measurement path length. The mode of the distribution of SL measurements in resting Langendorff-perfused heart is 1.95 μm (n = 167 measurements from N = 11 hearts) after correction for tissue orientation, which was significantly greater than that in isolated cells (1.71 μm, n = 346, N = 9 isolations) or ventricular slice preparations (1.79 μm, n = 79, N = 3 hearts) under our experimental conditions. Furthermore, we find that edema in arrested Langendorff-perfused heart is associated with a mean SL increase; this occurs as a function of time ex vivo and correlates with tissue volume changes determined by magnetic resonance imaging. Our results highlight that the proposed method can be used to monitor SL in living cells and that different experimental models from the same species may display significantly different SL values under otherwise comparable conditions, which has implications for experiment design, as well as comparison and interpretation of data. PMID:20228259

  6. Diffraction effects in length measurements by laser interferometry.

    PubMed

    Sasso, C P; Massa, E; Mana, G

    2016-03-21

    High-accuracy dimensional measurements by laser interferometers require corrections because of diffraction, which makes the effective fringe-period different from the wavelength of a plane (or spherical) wave λ0. By using a combined X-ray and optical interferometer as a tool to investigate diffraction across a laser beam, we observed wavelength variations as large as 10-8λ0. We show that they originate from the wavefront evolution under paraxial propagation in the presence of wavefront- and intensity-profile perturbations. PMID:27136842

  7. Subpicometer Length Measurement Using Semiconductor Laser Tracking Frequency Gauge

    NASA Technical Reports Server (NTRS)

    Thapa, Rajesh; Phillips, James D.; Rocco, Emanuele; Reasenburg, Robert D.

    2011-01-01

    We have demonstrated heretofore unattained distance precision of 0:14pm (2pm) incremental and 14nm (2.9 micrometers) absolute in a resonant (nonresonant) interferometer at an averaging time of 1 s, using inexpensive telecommunications diode lasers. We have controlled the main source of error, that due to spurious reflection and the resulting amplitude modulation. In the resonant interferometer, absolute distance precision is well under lambda/6. Therefore, after an interruption, an absolute distance measurement can be used to return to the same interferometer order.

  8. Bunch Length and Impedance Measurements at SPEAR3

    SciTech Connect

    Corbett, W.J.; Cheng, W.X.; Fisher, A.S.; Huang, X.; /SLAC

    2011-11-02

    Streak camera measurements were made at SPEAR3 to characterize longitudinal coupling impedance. For the nominal optics, data was taken at three rf voltages and a single-bunch current range of 0-20mA. Both bunchcentroid phase shift and bunch lengthening were recorded to extract values for resistive and reactive impedance. An (R+L) and a Q=1 model were then back-substituted into the Haissinski equation and compared with raw profile data. In the short bunch (low-{alpha}) mode, distribution 'bursting' was observed.

  9. FIBER LENGTH DISTRIBUTION MEASUREMENT FOR LONG GLASS AND CARBON FIBER REINFORCED INJECTION MOLDED THERMOPLASTICS

    SciTech Connect

    Kunc, Vlastimil; Frame, Barbara J; Nguyen, Ba N.; TuckerIII, Charles L.; Velez-Garcia, Gregorio

    2007-01-01

    Procedures for fiber length distribution (FLD) measurement of long fiber reinforced injection molded thermoplastics were refined for glass and carbon fibers. Techniques for sample selection, fiber separation, digitization and length measurement for both fiber types are described in detail. Quantitative FLD results are provided for glass and carbon reinforced polypropylene samples molded with a nominal original fiber length of 12.7 mm (1/2 in.) using equipment optimized for molding short fiber reinforced thermoplastics.

  10. Measurement of focal length using phase shifted moiré deflectometry

    NASA Astrophysics Data System (ADS)

    Trivedi, Satyaprakash; Dhanotia, Jitendra; Prakash, Shashi

    2013-06-01

    In present communication, a simple technique for determining the focal length using moiré deflectometry has been proposed. Necessary mathematical premise expressing the focal length of lens in terms of defocusing distance and the slope of wavefront phase has been deduced. Using a four-step phase shifting technique the testing procedure for determining the focal length has been demonstrated. Uncertainty in measurement has been estimated. Good co-relation between the measured value and the standard value has been obtained.

  11. Evolution equation for geometric quantum correlation measures

    NASA Astrophysics Data System (ADS)

    Hu, Ming-Liang; Fan, Heng

    2015-05-01

    A simple relation is established for the evolution equation of quantum-information-processing protocols such as quantum teleportation, remote state preparation, Bell-inequality violation, and particularly the dynamics of geometric quantum correlation measures. This relation shows that when the system traverses the local quantum channel, various figures of merit of the quantum correlations for different protocols demonstrate a factorization decay behavior for dynamics. We identified the family of quantum states for different kinds of quantum channels under the action of which the relation holds. This relation simplifies the assessment of many quantum tasks.

  12. Young Children's Understandings of Length Measurement: Evaluating a Learning Trajectory

    ERIC Educational Resources Information Center

    Szilagyi, Janka; Clements, Douglas H.; Sarama, Julie

    2013-01-01

    This study investigated the development of length measurement ideas in students from prekindergarten through 2nd grade. The main purpose was to evaluate and elaborate the developmental progression, or levels of thinking, of a hypothesized learning trajectory for length measurement to ensure that the sequence of levels of thinking is consistent…

  13. Monitoring quantum transport: Backaction and measurement correlations

    NASA Astrophysics Data System (ADS)

    Hussein, Robert; Gómez-García, Jorge; Kohler, Sigmund

    2014-10-01

    We investigate a tunnel contact coupled to a double quantum dot (DQD) and employed as a charge monitor for the latter. We consider both the classical limit and the quantum regime. In the classical case, we derive measurement correlations from conditional probabilities, yielding quantitative statements about the parameter regime in which the detection scheme works well. Moreover, we demonstrate that not only the DQD occupation but also the corresponding current may strongly correlate with the detector current. The quantum-mechanical solution, obtained with a Bloch-Redfield master equation, shows that the backaction of the measurement tends to localize the DQD electrons, and thus significantly reduces the DQD current. Moreover, it provides the effective parameters of the classical treatment. It turns out that already the classical description is adequate for most operating regimes.

  14. High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria.

    PubMed

    Tutterrow, Yeung Lo; Salanti, Ali; Avril, Marion; Smith, Joseph D; Pagano, Ian S; Ako, Simon; Fogako, Josephine; Leke, Rose G F; Taylor, Diane Wallace

    2012-01-01

    VAR2CSA mediates sequestration of Plasmodium falciparum-infected erythrocytes in the placenta, increasing the risk of poor pregnancy outcomes. Naturally acquired antibodies (Ab) to placental parasites at delivery have been associated with improved pregnancy outcomes, but Ab levels and how early in pregnancy Ab must be present in order to eliminate placental parasites before delivery remains unknown. Antibodies to individual Duffy-binding like domains of VAR2CSA have been studied, but the domains lack many of the conformational epitopes present in full-length VAR2CSA (FV2). Thus, the purpose of this study was to describe the acquisition of Ab to FV2 in women residing in high and low transmission areas and determine how Ab levels during pregnancy correlate with clearance of placental parasites. Plasma samples collected monthly throughout pregnancy from pregnant women living in high and low transmission areas in Cameroon were evaluated for Ab to FV2 and the proportion of high avidity Ab (i.e., Ab that remain bound in the presence of 3M NH(4)SCN) was assessed. Ab levels and proportion of high avidity Ab were compared between women with placental malaria (PM(+)) and those without (PM(-)) at delivery. Results showed that PM(-) women had significantly higher Ab levels (p = 0.0047) and proportion of high avidity Ab (p = 0.0009) than PM(+) women throughout pregnancy. Specifically, women with moderate to high Ab levels (>5,000 MFI) and those with ≥ 35% high avidity Ab at 5-6 months were found to have 2.3 (95% CI, 1.0-4.9) and 7.6-fold (p = 0.0013, 95% CI: 1.2-50.0) reduced risk of placental malaria, respectively. These data show that high levels of Ab to FV2, particularly those with high avidity for FV2, produced by mid-pregnancy are important in clearing parasites from the placenta. Both high Ab levels and proportion of high avidity Ab to FV2 may serve as correlates of protection for assessing immunity against placental malaria. PMID:22761948

  15. Focal length measurement based on the wavefront difference method by a Fizeau interferometer.

    PubMed

    Yang, Zhongming; Gao, Zhishan; Dou, Jiantai; Wang, Xinxing

    2014-09-01

    A method for measuring the focal length of the lens by a Fizeau interferometer is proposed. Based on the Gaussian imaging equation and the longitudinal displacements of the object point and image point, a precise formula for focal length calculation is deduced. The longitudinal displacement of the object points is determined by the wavefront difference method with a subnanometer resolution. An experimental system for focal length measurements is set up to verify the principle. The sources of uncertainty in measurement are discussed. Both the positive and negative lens experimental results indicate that the measurement accuracy is less than 0.16% under normal experimental environment. PMID:25321352

  16. Nonsymmetrized correlations in quantum noninvasive measurements.

    PubMed

    Bednorz, Adam; Bruder, Christoph; Reulet, Bertrand; Belzig, Wolfgang

    2013-06-21

    A long-standing problem in quantum mesoscopic physics is which operator order corresponds to noise expressions like , where I(ω) is the measured current at frequency ω. Symmetrized order describes a classical measurement while nonsymmetrized order corresponds to a quantum detector, e.g., one sensitive to either emission or absorption of photons. We show that both order schemes can be embedded in quantum weak-measurement theory taking into account measurements with memory, characterized by a memory function which is independent of a particular experimental detection scheme. We discuss the resulting quasiprobabilities for different detector temperatures and how their negativity can be tested on the level of second-order correlation functions already. Experimentally, this negativity can be related to the squeezing of the many-body state of the transported electrons in an ac-driven tunnel junction. PMID:23829718

  17. Nonsymmetrized Correlations in Mesoscopic Current Measurements

    NASA Astrophysics Data System (ADS)

    Belzig, Wolfgang; Bednorz, Adam; Bruder, Christoph; Reulet, Bertrand

    2014-03-01

    A long-standing problem in quantum mesoscopic physics is which operator order corresponds to noise expressions like < I(ω) I(- ω) > , where I(ω) is the measured current at frequency ω. Symmetrized order describes a classical measurement while nonsymmetrized order corresponds to a quantum detector, e.g., one sensitive to either emission or absorption of photons. We show that both order schemes can be embedded in quantum weak-measurement theory taking into account measurements with memory, characterized by a memory function which is independent of a particular experimental detection scheme [A. Bednorz, C. Bruder, B. Reulet, and W. Belzig, Phys. Rev. Lett. 110, 250404 (2013)]. We discuss the resulting quasiprobabilities for different detector temperatures and how their negativity can be tested on the level of second-order correlation functions already. Experimentally, this negativity can be related to the squeezing of the many-body state of the transported electrons in an ac-driven tunnel junction.

  18. Modeling the Length Effect: Specifying the Relation with Visual and Phonological Correlates of Reading

    ERIC Educational Resources Information Center

    van den Boer, Madelon; de Jong, Peter F.; Haentjens-van Meeteren, Marleen M.

    2013-01-01

    Beginning readers' reading latencies increase as words become longer. This length effect is believed to be a marker of a serial reading process. We examined the effects of visual and phonological skills on the length effect. Participants were 184 second-grade children who read 3- to 5-letter words and nonwords. Results indicated that reading…

  19. Correlating the internal length in strain gradient plasticity theory with the microstructure of material

    NASA Astrophysics Data System (ADS)

    Zhao, Jianfeng; Zhang, Xu; Konstantinidis, Avraam A.; Kang, Guozheng

    2015-06-01

    The internal length is the governing parameter in strain gradient theories which among other things have been used successfully to interpret size effects at the microscale. Physically, the internal length is supposed to be related with the microstructure of the material and evolves during the deformation. Based on Taylor hardening law, we propose a power-law relationship to describe the evolution of the variable internal length with strain. Then, the classical Fleck-Hutchinson strain gradient theory is extended with a strain-dependent internal length, and the generalized Fleck-Hutchinson theory is confirmed here, by comparing our model predictions to recent experimental data on tension and torsion of thin wires with varying diameter and grain size. Our work suggests that the internal length is a configuration-dependent parameter, closely related to dislocation characteristics and grain size, as well as sample geometry when this affects either the underlying microstructure or the ductility of the material.

  20. Exciton diffusion lengths of organic semiconductor thin films measured by spectrally resolved photoluminescence quenching

    NASA Astrophysics Data System (ADS)

    Lunt, Richard R.; Giebink, Noel C.; Belak, Anna A.; Benziger, Jay B.; Forrest, Stephen R.

    2009-03-01

    We demonstrate spectrally resolved photoluminescence quenching as a means to determine the exciton diffusion length of several archetype organic semiconductors used in thin film devices. We show that aggregation and crystal orientation influence the anisotropy of the diffusion length for vacuum-deposited polycrystalline films. The measurement of the singlet diffusion lengths is found to be in agreement with diffusion by Förster transfer, whereas triplet diffusion occurs primarily via Dexter transfer.

  1. Investigating the accuracy of parentally reported weights and lengths at 12 months of age as compared to measured weights and lengths in a longitudinal childhood genome study

    PubMed Central

    Hazrati, Sahel; Hourigan, Suchitra K; Waller, Allison; Yui, Yvonne; Gilchrist, Nancy; Huddleston, Kathi; Niederhuber, John

    2016-01-01

    Background Childhood obesity studies rely on parentally reported anthropometrics. However, the accuracy of such data has not been evaluated for 12-month-old children. Moreover, methods to improve the accuracy of reported data have not been assessed in prior studies. Methods A total of 185 children enrolled in a northern Virginia childhood longitudinal cohort genomic study had parentally completed surveys at 12 months. Measured weights and lengths were recorded for the same children from their 12-month paediatrician visit. Weight for length percentiles were calculated using World Health Organization gender-specific growth charts. The agreement between reported and measured values was examined using Pearson's correlation, paired t-test and κ statistics. The interquartile outlier rule was used to detect and remove outliers. Results Parentally reported weight was strongly associated with measured weight at 12 months (r=0.90). There was only a moderate correlation between parentally reported and measured lengths (r=0.52) and calculated weight for length percentiles (r=0.65). After removing outliers from parentally reported data, there was an increase in correlation between parentally reported and measured data for weight (r=0.93), length (r=0.69) and weight for length percentiles (r=0.76). Outliers removed compared to all children included were more likely to have maternal education less than a bachelor's degree (p=0.007). Conclusions After removal of outliers from reported data, there is a strong correlation between calculated reported and measured weight for length percentiles suggesting that this may be an effective method to increase accuracy when conducting large-scale obesity studies in young children where study costs benefit from using parentally reported data. PMID:27491670

  2. Measuring system for cable length and diameter based on photoelectric technology

    NASA Astrophysics Data System (ADS)

    Zhu, WeiMin; Zhou, Zhou; Wei, Ping; Qi, Fang

    2012-10-01

    Precise online measurement of cable diameter and length will ensure stability of quality production and production speed. This paper describes a measuring device to measure cable length and diameter simultaneously, accomplish online production process control. The device consists mainly of a synchronous sampling part, calculation and control part. The synchronous sampling part consists of two parallel rollers one meter far from each other. A measuring band cinctures the rollers and move together with them. There are two electromagnetic chucks on the measuring band which are controlled by two photoelectric position switches to hold or release a cable, in order to make the cable move with measuring system synchronously. An optical encoder is connected to one of the rollers coaxially to measure cable length. For cable diameter measurement, two orthogonal CCD sensors are used. Accuracy of online diameter measurement is mainly affected by vibration of cable movement. In order to reduce the cable diameter measurement error caused by vibration, measuring system uses a mechanical damping device and high-speed CCD sensors which exposure time is up to microseconds. The calculation and control part of measuring device can filter, amplify and binarizate electrical signals from synchronous sampling part, then they are processed by microcontroller 8051 to complete cable length and diameter measurement. As well, the measuring device can set error limits and detect online whether cable length and diameter size are in default range , if not it would give corresponding alarm.

  3. Eddy Correlation Flux Measurement System Handbook

    SciTech Connect

    Cook, D. R.

    2016-01-01

    The eddy correlation (ECOR) flux measurement system provides in situ, half-hour measurements of the surface turbulent fluxes of momentum, sensible heat, latent heat, and carbon dioxide (CO2) (and methane at one Southern Great Plains extended facility (SGP EF) and the North Slope of Alaska Central Facility (NSA CF). The fluxes are obtained with the eddy covariance technique, which involves correlation of the vertical wind component with the horizontal wind component, the air temperature, the water vapor density, and the CO2 concentration. The instruments used are: • a fast-response, three-dimensional (3D) wind sensor (sonic anemometer) to obtain the orthogonal wind components and the speed of sound (SOS) (used to derive the air temperature) • an open-path infrared gas analyzer (IRGA) to obtain the water vapor density and the CO2 concentration, and • an open-path infrared gas analyzer (IRGA) to obtain methane density and methane flux at one SGP EF and at the NSA CF. The ECOR systems are deployed at the locations where other methods for surface flux measurements (e.g., energy balance Bowen ratio [EBBR] systems) are difficult to employ, primarily at the north edge of a field of crops. A Surface Energy Balance System (SEBS) has been installed collocated with each deployed ECOR system in SGP, NSA, Tropical Western Pacific (TWP), ARM Mobile Facility 1 (AMF1), and ARM Mobile Facility 2 (AMF2). The surface energy balance system consists of upwelling and downwelling solar and infrared radiometers within one net radiometer, a wetness sensor, and soil measurements. The SEBS measurements allow the comparison of ECOR sensible and latent heat fluxes with the energy balance determined from the SEBS and provide information on wetting of the sensors for data quality purposes. The SEBS at one SGP and one NSA site also support upwelling and downwelling PAR measurements to qualify those two locations as Ameriflux sites.

  4. Experience of the fibrotest for measuring cotton fiber length and strength properties

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Fibrotest is a device developed by Textechno for measuring cotton fiber length and strength properties. The Fibrotest provides abundant information, including more than 20 length and strength parameters in absolute and relative modes, and displays fibrogram, load-elongation curve, and fiber bea...

  5. Quantifying precision of in situ length and weight measurements of fish

    USGS Publications Warehouse

    Gutreuter, S.; Krzoska, D.J.

    1994-01-01

    We estimated and compared errors in field-made (in situ) measurements of lengths and weights of fish. We made three measurements of length and weight on each of 33 common carp Cyprinus carpio, and on each of a total of 34 bluegills Lepomis macrochirus and black crappies Pomoxis nigromaculatus. Maximum total lengths of all fish were measured to the nearest 1 mm on a conventional measuring board. The bluegills and black crappies (85–282 mm maximum total length) were weighed to the nearest 1 g on a 1,000-g spring-loaded scale. The common carp (415–600 mm maximum total length) were weighed to the nearest 0.05 kg on a 20-kg spring-loaded scale. We present a statistical model for comparison of coefficients of variation of length (Cl ) and weight (Cw ). Expected Cl was near zero and constant across mean length, indicating that length can be measured with good precision in the field. Expected Cw decreased with increasing mean length, and was larger than expected Cl by 5.8 to over 100 times for the bluegills and black crappies, and by 3 to over 20 times for the common carp. Unrecognized in situ weighing errors bias the apparent content of unique information in weight, which is the information not explained by either length or measurement error. We recommend procedures to circumvent effects of weighing errors, including elimination of unnecessary weighing from routine monitoring programs. In situ weighing must be conducted with greater care than is common if the content of unique and nontrivial information in weight is to be correctly identified.

  6. Analysis on the Time-Lag Correlation for the Changes of the Length of the Day and Geomagnetic Field

    NASA Astrophysics Data System (ADS)

    Gao, Guo-Ming; Kang, Guo-Fa; Bai, Chun-Hua; Li, Wei

    2007-06-01

    Two data sets including the historical geomagnetic field model and the length of the day are used to analyze the correlation characteristics of the geomagnetic field variation and the changes in the length of the day from 1840-2000. The results show that a lag correlation is available in the changes of geomagnetic field and the length od the day. The geomagnetic intensity parameter is approximately exceeding LOD by 7.5-10 year. However the geomagnetic western drift parameters lag behind LOD variation, the western drift components lag behind LOD by 7.5 years, the average drifting speed and the latitudinal drifting components of the geomagnetic filed lag behind LOD by 20-22.5 years.

  7. Direct measurement of the plasma screening length and surface potential near the lunar terminator

    NASA Technical Reports Server (NTRS)

    Benson, J.

    1977-01-01

    Direct measurement of the lunar dayside surface potential and screening length has been made by the suprathermal ion detector experiment (Side) near the terminator. In a region 20-30 deg from the terminator at the Apollo 14 and 15 sites the surface potential is found to be approximately 50 V negative, and the screening length to be about 1 km. This value of the screening length is more than 2 orders of magnitude greater than the solar wind 'Debye' length. The strong negative surface potential in this region may be due to enhanced temperature and density of the solar wind plasma.

  8. ATLAS-3 correlative measurement opportunities with UARS and surface observations

    NASA Technical Reports Server (NTRS)

    Harrison, Edwin F.; Denn, Fred M.; Gibson, Gary G.

    1995-01-01

    The third ATmospheric Laboratory for Applications and Science (ATLAS-3) mission was flown aboard the Space Shuttle launched on November 3, 1994. The mission length was approximately 10 days and 22 hours. The ATLAS-3 Earth-viewing instruments provided a large number of measurements which were nearly coincident with observations from experiments on the Upper Atmosphere Research Satellite (UARS). Based on ATLAS-3 instrument operating schedules, simulations were performed to determine when and where correlative measurements occurred between ATLAS and UARS instruments, and between ATLAS and surface observations. Results of these orbital and instrument simulations provide valuable information for scientists to compare measurements between various instruments on the two satellites and at selected surface sites.

  9. Cosmological measurements with general relativistic galaxy correlations

    NASA Astrophysics Data System (ADS)

    Raccanelli, Alvise; Montanari, Francesco; Bertacca, Daniele; Doré, Olivier; Durrer, Ruth

    2016-05-01

    We investigate the cosmological dependence and the constraining power of large-scale galaxy correlations, including all redshift-distortions, wide-angle, lensing and gravitational potential effects on linear scales. We analyze the cosmological information present in the lensing convergence and in the gravitational potential terms describing the so-called ``relativistic effects'', and we find that, while smaller than the information contained in intrinsic galaxy clustering, it is not negligible. We investigate how neglecting them does bias cosmological measurements performed by future spectroscopic and photometric large-scale surveys such as SKA and Euclid. We perform a Fisher analysis using the CLASS code, modified to include scale-dependent galaxy bias and redshift-dependent magnification and evolution bias. Our results show that neglecting relativistic terms, especially lensing convergence, introduces an error in the forecasted precision in measuring cosmological parameters of the order of a few tens of percent, in particular when measuring the matter content of the Universe and primordial non-Gaussianity parameters. The analysis suggests a possible substantial systematic error in cosmological parameter constraints. Therefore, we argue that radial correlations and integrated relativistic terms need to be taken into account when forecasting the constraining power of future large-scale number counts of galaxy surveys.

  10. d + Au hadron correlation measurements from PHENIX

    NASA Astrophysics Data System (ADS)

    Sickles, Anne M.

    2015-01-01

    Recent observations of extended pseudorapidity correlations at the LHC in p+p and p+Pb collisions are of great interest. Here we present related results from d+Au collisions at PHENIX. We present the observed v2 and discuss the possible origin in the geometry of the collision region. We also present new measurements of the pseudorapidity dependence of the ridge in d+Au collision. Future plans to clarify the role of geometry in small collision systems using 3 He + Au collisions are discussed.

  11. Importance of the Correlation between Width and Length in the Shape Analysis of Nanorods: Use of a 2D Size Plot To Probe Such a Correlation.

    PubMed

    Zhao, Zhihua; Zheng, Zhiqin; Roux, Clément; Delmas, Céline; Marty, Jean-Daniel; Kahn, Myrtil L; Mingotaud, Christophe

    2016-08-22

    Analysis of nanoparticle size through a simple 2D plot is proposed in order to extract the correlation between length and width in a collection or a mixture of anisotropic particles. Compared to the usual statistics on the length associated with a second and independent statistical analysis of the width, this simple plot easily points out the various types of nanoparticles and their (an)isotropy. For each class of nano-objects, the relationship between width and length (i.e., the strong or weak correlations between these two parameters) may suggest information concerning the nucleation/growth processes. It allows one to follow the effect on the shape and size distribution of physical or chemical processes such as simple ripening. Various electron microscopy pictures from the literature or from the authors' own syntheses are used as examples to demonstrate the efficiency and simplicity of the proposed 2D plot combined with a multivariate analysis. PMID:27460632

  12. Cesium oscillator strengths measured with a multiple-path-length absorption cell

    NASA Technical Reports Server (NTRS)

    Exton, R. J.

    1976-01-01

    Absorption-oscillator-strength measurements for the principal series in cesium were measured using a multiple-path-length cell. The optical arrangement included a movable transverse path for checking the uniformity of the alkali density along the length of the cell and which also allowed strength measurements to be made simultaneously on both strong and weak lines. The strengths measured on the first 10 doublets indicate an increasing trend in the doublet ratio. The individual line strengths are in close agreement with the high resolution measurements of Pichler (1974) and with the calculations of Norcross (1973).

  13. A comparison of two methods for measuring vessel length in woody plants.

    PubMed

    Pan, Ruihua; Geng, Jing; Cai, Jing; Tyree, Melvin T

    2015-12-01

    Vessel lengths are important to plant hydraulic studies, but are not often reported because of the time required to obtain measurements. This paper compares the fast dynamic method (air injection method) with the slower but traditional static method (rubber injection method). Our hypothesis was that the dynamic method should yield a larger mean vessel length than the static method. Vessel length was measured by both methods in current year stems of Acer, Populus, Vitis and Quercus representing short- to long-vessel species. The hypothesis was verified. The reason for the consistently larger values of vessel length is because the dynamic method measures air flow rates in cut open vessels. The Hagen-Poiseuille law predicts that the air flow rate should depend on the product of number of cut open vessels times the fourth power of vessel diameter. An argument is advanced that the dynamic method is more appropriate because it measures the length of the vessels that contribute most to hydraulic flow. If all vessels had the same vessel length distribution regardless of diameter, then both methods should yield the same average length. This supports the hypothesis that large-diameter vessels might be longer than short-diameter vessels in most species. PMID:26084355

  14. [Shushu (ancient Chinese numerology) in Lingshu: Gudu (Miraculous Pivot: Bone-Length Measurement)].

    PubMed

    Zhuo, Lian-Shi

    2010-10-01

    Lingshu: Gudu (Miraculous Pivot: Bone-Length Measurement) is compared with literatures concerning the Shushu (ancient Chinese numerology) of the Qin Dynasty (221 B. C. - 206 B. C. ) and the Han Dynasty (206 B. C.-220 A. D.) in this article. And it is discovered that "the number of heaven and earth" in Yijing (The Book of Change) was implied in the bone-length measurement. The theory of Shushu is hidden in the sized of head, neck, chest, abdomen, back and 4 extremities according to the measurement. The meaning of establishment of bone-length measurement, which is found to have universality, laid in setting down the measurement of meridians. And it is the origin of the proportional measurement of locating acupoints. Checked with the theory of Shushu, errors in the description of bone-length measurement could also be found in Lingshu: Gudu (Miraculous Pivot: Bone-Length Measurement) of the present edition, which is helpful for the modern study on the measurement. PMID:21058490

  15. Modified Sagnac interferometer for contact-free length measurement of a direct absorption cell.

    PubMed

    Elandaloussi, Hadj; Rouillé, Christian; Marie-Jeanne, Patrick; Janssen, Christof

    2016-03-10

    Accurate path length measurements in absorption cells are recurrent requirements in quantitative molecular absorption spectroscopy. A new twin path laser interferometer for length measurements in a simple direct path absorption geometry is presented, along with a full uncertainty budget. The path in an absorption cell is determined by measuring the optical path length change due to the diminution of the refractive index when the cell originally filled with nitrogen gas is evacuated. The performance of the instrument based on a stabilized HeNe laser is verified by comparison with the results of direct mechanical length measurements of a roughly 45 mm long, specially designed absorption cell. Due to a resolution of about 1/300 of a HeNe fringe, an expanded (coverage factor k=2) uncertainty of 16 μm in the length measurement is achieved, providing an expanded relative uncertainty of 3.6·10⁻⁴ for the length of our test absorption cell. This value is about 8 times lower than what has been reported previously. The instrument will be useful for precision measurements of absorption cross sections of strong absorbers which require short light paths, such as ozone, halogen oxides, sulfur dioxide, and volatile organic compounds in the UV. PMID:26974791

  16. Polarization gating enables sarcomere length measurements by laser diffraction in fibrotic muscle

    NASA Astrophysics Data System (ADS)

    Young, Kevin W.; Dayanidhi, Sudarshan; Lieber, Richard L.

    2014-11-01

    Sarcomere length is a key parameter commonly measured in muscle physiology since it dictates striated muscle active force. Laser diffraction (LD)-based measurements of sarcomere length are time-efficient and sample a greater number of sarcomeres compared with traditional microscopy-based techniques. However, a limitation to LD techniques is that signal quality is severely degraded by scattering events as photons propagate through tissue. Consequently, sarcomere length measurements are unattainable when the number of scattering events is sufficiently large in muscle tissue with a high scattering probability. This occurs in fibrotic skeletal muscle seen in muscular dystrophies and secondary to tissue trauma, thus eliminating the use of LD to study these skeletal muscle ailments. Here, we utilize polarization gating to extract diffracted signals that are buried in noise created by scattering. Importantly, we demonstrate that polarization-gated laser diffraction (PGLD) enables sarcomere length measurements in muscles from chronically immobilized mice hind limbs; these muscles have a substantial increase of intramuscular connective tissue that scatter light and disable sarcomere length measurements by traditional LD. Further, we compare PGLD sarcomere lengths to those measured by bright field (BF) and confocal microscopy as positive controls and reveal a significant bias of BF but not of confocal microscopy.

  17. Reliability of measuring pectoralis minor muscle resting length in subjects with and without signs of shoulder impingement

    PubMed Central

    Rosa, Dayana P.; Borstad, John D.; Pires, Elisa D.; Camargo, Paula R.

    2016-01-01

    Background: Pectoralis minor adaptive shortening may change scapula resting position and scapular kinematics during arm elevation. A reliable and clinically feasible method for measuring pectoralis minor length will be useful for clinical decision making when evaluating and treating individuals with shoulder pain and dysfunction. Objectives: To evaluate intrarater, interrater, and between-day reliability of a pectoralis minor (PM) muscle length measurement in subjects with and without signs of shoulder impingement. Method: A convenience sample of 100 individuals (50 asymptomatic and 50 symptomatic) participated in this study. Intra- and interrater reliability of the measurement was estimated in 50 individuals (25 asymptomatic and 25 symptomatic), and between-day reliability of the measurement repeated over an interval of 7 days was estimated in an independent sample of 50 additional participants. Pectoralis minor length was measured using a flexible tape measure with subjects standing. Results: Intraclass correlation coefficients (ICC3,k) for intrarater and interrater reliability ranged from 0.86-0.97 and 0.95 for between-day reliability in both groups. Standard error of measurements (SEM) ranged from 0.30-0.42 cm, 0.70-0.84 cm, and 0.40-0.41 cm for intrarater, interrater, and between-day reliability, respectively, across the sample. The minimal detectable change (MDC) for between-day measurements ranged from 1.13-1.14 cm for both groups. Conclusions: In asymptomatic individuals and in those with signs of shoulder impingement, a single rater or pair of raters can measure pectoralis minor muscle length using a tape measure with very good reliability. This measurement can also be reliably used by the same rater over a seven day interval. PMID:26982455

  18. Focal length and radius of curvature measurement using wavefront difference method

    NASA Astrophysics Data System (ADS)

    Yang, Zhongming; Gao, Zhishan; Wang, Shuai; Cheng, Jinlong; Yuan, Qun

    2015-10-01

    A method for measuring the focal length of the lens and the radius of curvature of the spherical surface using wavefront difference method is proposed. Based on Fizeau interferometer, an experimental system for focal length measurements is set up to verify the principle. Based on the point diffraction interferometer, an experimental system for radius of curvature measurements is proposed to verify the proposed method. With the focal length testing system, both the positive and negative lens experimental results indicate that the measurement accuracy is less than 0.16%under normal experimental environment. With the radius of curvature testing system, the radius of curvature of spherical mirrors and the surface figure can be measured in a higher precision simultaneously. The experimental results indicate that the measurement accuracy is in the order of 10-4 .

  19. Automatic interface measurement and analysis. [shoreline length of Alabama using LANDSAT imagery

    NASA Technical Reports Server (NTRS)

    Faller, K. H.

    1975-01-01

    A technique for detecting and measuring the interface between two categories in classified scanner data is described together with two application demonstrations. Measurements were found to be accurate to 1.5% root mean square error on features of known length while comparison of measurements made using the technique on LANDSAT data to opisometer measurements on 1:24,000 scale maps shows excellent agreement. Application of the technique to two frames of LANDSAT data classified using a two channel, two class classifier resulted in a computation of 64 km annual decrease in shoreline length. The tidal shoreline of a portion of Alabama was measured using LANDSAT data. Based on the measurement of this portion, the total tidal shoreline length of Alabama is estimated to be 1313 kilometers.

  20. Prospective Secondary Mathematics Teachers' Pedagogical Knowledge for Teaching the Estimation of Length Measurements

    ERIC Educational Resources Information Center

    Subramaniam, Karthigeyan

    2014-01-01

    Prospective secondary mathematics teachers' pedagogical knowledge for teaching the estimation of length measurements was investigated by examining their personal benchmarks for measurement estimation. Benchmarks for measurement estimation are the meaningful representations of units that serve to increase one's understanding of…

  1. Laser multi-reflection differential confocal long focal-length measurement.

    PubMed

    Li, Zhigang; Qiu, Lirong; Zhao, Weiqian; Zhao, Qi

    2016-06-20

    We propose a new laser multi-reflection differential confocal focal-length measurement (LDCFM) method to meet the requirements of high-precision measurements of long focal lengths. An optical flat and a reflector are placed behind a test lens for reflecting the measuring beam repeatedly. Then, LDCFM uses the property that the null points of differential confocal response curves precisely correspond to the convergence points of the multi-reflected measuring beam to exactly determine the positions of the convergence points accurately. Subsequently, the position variation of the reflector is measured with different reflection times by using a distance-measuring instrument, and thereby the long focal length is measured precisely. Theoretical analyses and preliminary experimental results indicate that the LDCFM method has a relative expanded standard uncertainty (k=2) of 0.04% for the test lens with a focal length of 9.76 m. The LDCFM method can provide a novel approach for high-precision focal-length measurements. PMID:27409117

  2. Significant Enhancement of the Chiral Correlation Length in Nematic Liquid Crystals by Gold Nanoparticle Surfaces Featuring Axially Chiral Binaphthyl Ligands.

    PubMed

    Mori, Taizo; Sharma, Anshul; Hegmann, Torsten

    2016-01-26

    surface is diminished as the size of the particle is reduced. However, in comparison to the free ligands, per chiral molecule all tested gold nanoparticles induce helical distortions in a 10- to 50-fold larger number of liquid crystal host molecules surrounding each particle, indicating a significantly enhanced chiral correlation length. We propose that both the helicity and the chirality transfer efficiency of axially chiral binaphthyl derivatives can be controlled at metal nanoparticle surfaces by adjusting the particle size and curvature as well as the number and density of the chiral ligands to ultimately measure and tune the chiral correlation length. PMID:26735843

  3. Divergent selection for fiber length and bundle strength and correlated responses in cotton

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cotton breeders must develop cultivars to meet the demand for longer, stronger, and more uniform fibers. In the current study, two cycles of divergent selection for fiber upper-half mean length (UHML) and bundle strength (Str) were conducted within five diverse parental combinations selected based o...

  4. Exploring the spatial heterogeneity of terraced landscapes using LiDAR: the Slope Local Length of Auto-Correlation (SLLAC).

    NASA Astrophysics Data System (ADS)

    Sofia, Giulia; Marinello, Francesco; Tarolli, Paolo

    2014-05-01

    Length of Auto-Correlation", or SLLAC map. The SLLAC map texture is characterized by the presence of peculiar elongated fibers that change depending on the landscape morphology, and on the type of terracing system. The differences in texture can be measured, and they can be used to discriminate terraced areas from more natural ones. Given the raising importance of these landscapes, the proposed procedure can offer an important and promising tool to explore the spatial heterogeneity of terraced sites.

  5. In-process Measuring of Capacitance Per Unit Length for Single-core Electric Wires

    NASA Astrophysics Data System (ADS)

    Goldshtein, A. E.; Vavilova, G. V.; Mazikov, S. V.

    2016-01-01

    The paper describes technical in-process implementation of the electrical method to measure the electrical capacitance per unit length of a single core electric wire. The basic design values of the electro-capacitive measuring transducer are determined. The impact of changes in water conductivity on measurement results is analyzed. Techniques to offset from the impact of changes in water conductivity on the results of the electrical capacitance per unit length control based on indirect electrical conductivity measurement are considered. An appropriate correction of the conversion function is made.

  6. Tyre contact length on dry and wet road surfaces measured by three-axial accelerometer

    NASA Astrophysics Data System (ADS)

    Matilainen, Mika; Tuononen, Ari

    2015-02-01

    We determined the tyre contact length on dry and wet roads by measuring the accelerations of the inner liner with a three-axial accelerometer. The influence of the tyre pressure, driving velocity, and tread depth on the contact length was studied in both types of road surface conditions. On dry asphalt the contact length was almost constant, regardless of the driving velocity. On wet asphalt the presence of water could be detected even at low driving velocities (e.g. 20 km/h for a worn tyre) as the contact length began to decrease from that found in the dry asphalt situation. In addition to improving the performance of active safety systems and driver warning systems, the contact length information could be beneficial for classifying and studying the aquaplaning behaviour of tyres.

  7. Length Dependent Thermal Conductivity Measurements Yield Phonon Mean Free Path Spectra in Nanostructures

    PubMed Central

    Zhang, Hang; Hua, Chengyun; Ding, Ding; Minnich, Austin J.

    2015-01-01

    Thermal conductivity measurements over variable lengths on nanostructures such as nanowires provide important information about the mean free paths (MFPs) of the phonons responsible for heat conduction. However, nearly all of these measurements have been interpreted using an average MFP even though phonons in many crystals possess a broad MFP spectrum. Here, we present a reconstruction method to obtain MFP spectra of nanostructures from variable-length thermal conductivity measurements. Using this method, we investigate recently reported length-dependent thermal conductivity measurements on SiGe alloy nanowires and suspended graphene ribbons. We find that the recent measurements on graphene imply that 70% of the heat in graphene is carried by phonons with MFPs longer than 1 micron. PMID:25764977

  8. Length dependent thermal conductivity measurements yield phonon mean free path spectra in nanostructures.

    PubMed

    Zhang, Hang; Hua, Chengyun; Ding, Ding; Minnich, Austin J

    2015-01-01

    Thermal conductivity measurements over variable lengths on nanostructures such as nanowires provide important information about the mean free paths (MFPs) of the phonons responsible for heat conduction. However, nearly all of these measurements have been interpreted using an average MFP even though phonons in many crystals possess a broad MFP spectrum. Here, we present a reconstruction method to obtain MFP spectra of nanostructures from variable-length thermal conductivity measurements. Using this method, we investigate recently reported length-dependent thermal conductivity measurements on SiGe alloy nanowires and suspended graphene ribbons. We find that the recent measurements on graphene imply that 70% of the heat in graphene is carried by phonons with MFPs longer than 1 micron. PMID:25764977

  9. Correlation between anthropometric data and length and thickness of the tendons of the semitendinosus and gracilis muscles used for grafts in reconstruction of the anterior cruciate ligament☆

    PubMed Central

    Pereira, Rafael Noschang; Karam, Francisco Consoli; Schwanke, Roberto Luís; Millman, Rubens; Foletto, Zilmar Minetto; Schwanke, Carla Helena Augustin

    2016-01-01

    Objective Preoperative estimation of the length and diameter of the semitendinosus (ST) and gracilis (G) tendons can assist surgeons and allow them to have the opportunity to choose alternative grafts. The aim of this study was to investigate whether anthropometric measurements such as height, weight and body mass index (BMI) or the patient's age and sex have any correlation with the thickness and the length of ST and G tendons. Methods Data were gathered from 64 patients who underwent the surgical procedure of anterior cruciate ligament reconstruction using the tendons of the ST and G muscles as grafts, between June 2012 and August 2013. Variables such as age, sex, weight, height, body mass index (BMI) and length and diameter of the tendons of the ST and G muscles were analyzed. Results There was a positive correlation between the height and total diameter of the quadruple graft (r = 0.254; p = 0.043), total length of the ST tendon (r = 0.450; p < 0.01), diameter of the double ST (r = 0.270; p = 0.031), triple ST (r = 0.347; p = 0.005), length of G tendon (r = 0.249; p = 0.047) and diameter of the double-G (r = 0.258; p = 0.039). However, age (r = -0.015; p = 0.908), weight (r = 0.165; p = 0.193) and body mass index (r = 0.012; p = 0.926) showed no correlation. Conclusion Our results show that age, weight and BMI did not correlate with the diameter and length of the graft, while the height had a positive correlation with the total length of the flexor tendons and the diameter of the graft from the flexors (ST and G). PMID:27069886

  10. PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability.

    PubMed

    Godinho, Bruno M D C; Ogier, Julien R; Quinlan, Aoife; Darcy, Raphael; Griffin, Brendan T; Cryan, John F; O'Driscoll, Caitriona M

    2014-10-01

    Silencing disease-related genes in the central nervous system (CNS) using short interfering RNA (siRNA) holds great promise for treating neurological disorders. Yet, delivery of RNAi therapeutics to the brain poses major challenges to non-viral systems, especially when considering systemic administration. Cationic nanoparticles have been widely investigated for siRNA delivery, but the tendency of these to aggregate in physiological environments limits their intravenous application. Thus, strategies to increase the stability of nanoparticles have been developed. Here, we investigated the ability of modified cationic amphiphilic or PEGylated amphiphilic cyclodextrins (CD) to formulate stable CD.siRNA nanoparticles. To this end, we describe a simple method for post-modification of pre-formed cationic CD.siRNA nanoparticles at their surface using PEGylated CDs of different PEG lengths. PEGylated CD.siRNA nanoparticles presented reduced surface charges and increased stability in physiological salt conditions. Stability of PEGylated CD.siRNA nanoparticles in vitro increased with both PEG length and PEG density at the surface. Furthermore, in a comparative pharmacokinetic study, increased systemic exposure and reduced clearance were achieved with CD-formulations when compared to naked siRNAs. However, no significant differences were observed among non-PEGylated and PEGylated CD.siRNAs suggesting that longer PEG lengths might be required for improving stability in vivo. PMID:24992319

  11. Is it True That the Normal Valence-Length Correlation Is Irrelevant for Metal-Metal Bonds?

    PubMed

    Singh, Vijay; Dixit, Mudit; Kosa, Monica; Major, Dan Thomas; Levi, Elena; Aurbach, Doron

    2016-04-01

    The most intriguing feature of metal-metal bonds in inorganic compounds is an apparent lack of correlation between the bond order and the bond length. In this study, we combine a variety of literature data obtained by quantum chemistry and our results based on the empirical bond valence model (BVM), to confirm for the first time the existence of a normal exponential correlation between the effective bond order (EBO) and the length of the metal-metal bonds. The difference between the EBO and the formal bond order is attributed to steric conflict between the (TM)n cluster (TM=transition metal) and its environment. This conflict, affected mainly by structural type, should cause high lattice strains, but electron redistribution around TM atoms, evident from the BVM calculations, results in a full or partial strain relaxation. PMID:26929001

  12. Study on surface photovoltage measurement of long diffusion length silicon: Simulation results

    NASA Astrophysics Data System (ADS)

    Anttila, O. J.; Hahn, S. K.

    1993-07-01

    The limitations of surface photovoltage method (SPV), using the analytical solution for the minority-carrier distribution, are studied in detail. The principal source of error in thin wafers of long diffusion length material is the back surface recombination. The possibility of measuring large diffusion lengths in a reliable manner is discussed. With proper back surface passivation, diffusion lengths as long as several times the sample thickness can be measured. Evaluation of minor amounts of iron contamination in p-type material is possible even if the back surface recombination velocity is high, but a correction factor is required for the traditionally used relationship to convert the observed diffusion length change to iron concentration. The value of the correction factor varies between 1 and 1.5 for high back surface recombination velocity; the magnitude depends on the ratio between wafer thickness and the diffusion length of the minority carriers. The detection limit for iron is in the 109-1011 at/cm3 range, depending on the quality of the instrumentation and on the sample preparation; low back surface recombination gives better sensitivity. The use of SPV to measure the denuded zone width in precipitated material is briefly analyzed. It is shown that in heavily precipitated material an SPV measurement underestimates the denuded zone width, and the result will be very sensitive to the diffusion length in the bulk of the sample. Finally, the sensitivity of the measured diffusion length to different sources of errors and requirements for the sample preparation are discussed. The use of constant-flux method introduces some potential errors, which can be avoided through the use of constant bias illumination during the measurement.

  13. Simultaneous measurement of the root-mean-square roughness and autocorrelation length by optical method

    NASA Astrophysics Data System (ADS)

    Kim, Dalwoo; Oh, Ki-Jang; Lim, Choong-Soo

    1998-12-01

    We developed an on-line measurement system for the simultaneous measurement of the root-mean-square roughness and autocorrelation length which are the parameters of surface roughness. The measurement is based on the scattering theory of light on the rough surface. Computer simulation shows that the measurement range depends on the wavelength of the light source, and this is verified with the experiment. We installed the measurement system at the finishing line of a cold-rolling steel work, and measured the two parameters in situ. The rms roughness and autocorrelation length are measured and transformed in the average surface roughness and then umber of peaks per inch, respectively. The measured data for both of the parameters are compared with those of stylus method, an the optical method is well coincided with the conventional stylus method.

  14. Technique for the focal-length measurement of positive lenses using Fizeau interferometry

    SciTech Connect

    Pavan Kumar, Yeddanapudi; Chatterjee, Sanjib

    2009-02-01

    We present what we believe is a new technique for the focal-length measurement of positive lenses using Fizeau interferometery. The technique utilizes the Gaussian lens equation. The image distance is measured interferometrically in terms of the radius of curvature of the image-forming wavefront emerging from the lens. The radii of curvature of the image-forming wavefronts corresponding to two different axial object positions of known separation are measured. The focal length of the lens is determined by solving the equations obtained using the Gaussian lens equation for the two object positions. Results obtained for a corrected doublet lens of a nominal focal length of 200.0 mm with a measurement uncertainty of {+-}2.5% is presented.

  15. Reliability of linear distance measurement for dental implant length with standardized periapical radiographs.

    PubMed

    Wakoh, Mamoru; Harada, Takuya; Otonari, Takamichi; Otonari-Yamamoto, Mika; Ohkubo, Mai; Kousuge, Yuji; Kobayashi, Norio; Mizuta, Shigeru; Kitagawa, Hiromi; Sano, Tsukasa

    2006-08-01

    The purpose of this study was to investigate the accuracy of distance measurements of implant length based on periapical radiographs compared with that of other modalities. We carried out an experimental trial to compare precision in distance measurement. Dental implant fixtures were buried in the canine and first molar regions. These were then subjected to periapical (PE) radiography, panoramic (PA) radiography, conventional (CV) and medical computed (CT) tomography. The length of the implant fixture on each film was measured by nine observers and degree of precision was statistically analyzed. The precision of both PE radiographs and CT tomograms was closest at the highest level. Standardized PE radiography, in particular, was superior to CT tomography in the first molar region. This suggests that standardized PE radiographs should be utilized as a reliable modality for longitudinal and linear distance measurement, depending on implant length at local implantation site. PMID:17344618

  16. Calibration for the errors resulted from aberration in long focal length measurement

    NASA Astrophysics Data System (ADS)

    Yao, Jiang; Luo, Jia; He, Fan; Bai, Jian; Wang, Kaiwei; Hou, Xiyun; Hou, Changlun

    2014-09-01

    In this paper, a high-accuracy calibration method for errors resulted from aberration in long focal length measurement, is presented. Generally, Gaussian Equation is used for calculation without consideration of the errors caused by aberration. However, the errors are the key factor affecting the accuracy in the measurement system of a large aperture and long focal length lens. We creatively introduce an effective way to calibrate the errors, with detailed analysis of the long focal length measurement based on divergent light and Talbot interferometry. Aberration errors are simulated by Zemax. Then, we achieve auto-correction with the help of Visual C++ software and the experimental results reveal that the relative accuracy is better than 0.01%.By comparing modified values with experimental results obtained in knife-edge testing measurement, the proposed method is proved to be highly effective and reliable.

  17. Utilization of coincidence criteria in absolute length measurements by optical interferometry in vacuum and air

    NASA Astrophysics Data System (ADS)

    Schödel, R.

    2015-08-01

    Traceability of length measurements to the international system of units (SI) can be realized by using optical interferometry making use of well-known frequencies of monochromatic light sources mentioned in the Mise en Pratique for the realization of the metre. At some national metrology institutes, such as Physikalisch-Technische Bundesanstalt (PTB) in Germany, the absolute length of prismatic bodies (e.g. gauge blocks) is realized by so-called gauge-block interference comparators. At PTB, a number of such imaging phase-stepping interference comparators exist, including specialized vacuum interference comparators, each equipped with three highly stabilized laser light sources. The length of a material measure is expressed as a multiple of each wavelength. The large number of integer interference orders can be extracted by the method of exact fractions in which the coincidence of the lengths resulting from the different wavelengths is utilized as a criterion. The unambiguous extraction of the integer interference orders is an essential prerequisite for correct length measurements. This paper critically discusses coincidence criteria and their validity for three modes of absolute length measurements: 1) measurements under vacuum in which the wavelengths can be identified with the vacuum wavelengths, 2) measurements under air in which the air refractive index is obtained from environmental parameters using an empirical equation, and 3) measurements under air in which the air refractive index is obtained interferometrically by utilizing a vacuum cell placed along the measurement pathway. For case 3), which corresponds to PTB’s Kösters-Comparator for long gauge blocks, the unambiguous determination of integer interference orders related to the air refractive index could be improved by about a factor of ten when an ‘overall dispersion value,’ suggested in this paper, is used as coincidence criterion.

  18. 16 CFR 500.12 - Measurement of commodities by length and width, how expressed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... square foot (929 cm2) be expressed in terms of length and width in linear measure. The customary inch... the linear dimensions, the quantity of contents, in addition to being declared in the manner... statement of the linear dimensions of the largest unit of measurement, a parenthetical declaration of...

  19. The measurement of the optical cavity length for the Infrared Free-Electron Laser

    SciTech Connect

    C.J. Curtis; J.C. Dahlberg; W.A. Oren; K.J. Tremblay

    1999-10-01

    One of the final tasks involved in the alignment of the newly constructed Free Electron Laser at the Thomas Jefferson National Accelerator Facility was to accurately measure the length between two mirrors which make up the optical cavity. This presentation examines the survey techniques and equipment assembled in order to complete these measurements, together with the possible sources of error, and the accuracy achieved.

  20. 16 CFR 500.11 - Measurement of commodity length, how expressed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Measurement of commodity length, how expressed. 500.11 Section 500.11 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENT... REGULATIONS UNDER SECTION 4 OF THE FAIR PACKAGING AND LABELING ACT § 500.11 Measurement of commodity...

  1. Effects of Text Length on Lexical Diversity Measures: Using Short Texts with Less than 200 Tokens

    ERIC Educational Resources Information Center

    Koizumi, Rie; In'nami, Yo

    2012-01-01

    Despite the importance of lexical diversity (LD) in L2 speaking and writing performance, LD assessment measures are known to be affected by the number of words analyzed in the text. This study aims to identify LD measures that are least affected by text length and can be used for the analysis of short L2 texts (50-200 tokens). We compared the…

  2. Precision neutron interferometric measurement of the n- 3He coherent neutron scattering length

    NASA Astrophysics Data System (ADS)

    Huffman, P. R.; Jacobson, D. L.; Schoen, K.; Arif, M.; Black, T. C.; Snow, W. M.; Werner, S. A.

    2004-07-01

    A measurement of the n- 3He coherent scattering length using neutron interferometry is reported. The result, bc =(5.8572±0.0072) fm , improves the measured precision of any single measurement of bc by a factor of eight; the previous world average, bc =(5.74±0.04) fm , now becomes bc =(5.853±0.007) fm . Measurements of the n-p , n-d , and n- 3He coherent scattering lengths have now been performed using the same technique, thus allowing one to extract the scattering length ratios: parameters that minimize systematic errors. We obtain values of bn 3He / bnp =(-1.5668±0.0021) and bnd / bnp =(-1.7828±0.0014) . Using the new world average value of bc and recent high-precision spin-dependent scattering length data also determined by neutron optical techniques, we extract new values for the bound singlet and triple scattering lengths of b0 =(9.949±0.027) fm and b1 =(4.488±0.017) fm for the n- 3He system. The free nuclear singlet and triplet scattering lengths are a0 =(7.456±0.020) fm and a1 =(3.363±0.013) fm . The coherent scattering cross section is σc =(4.305±0.007) b and the total scattering cross section is σs =(5.837±0.014) b . Comparisons of a0 and a1 to the only existing high-precision theoretical predictions for the n- 3He system, calculated using a resonating group technique with nucleon-nucleon potentials incorporating three-nucleon forces, have been performed. Neutron scattering length measurements in few-body systems are now sensitive enough to probe small effects not yet adequately treated in present theoretical models.

  3. The Commissioning Of A Three Dimensional Depolarized Neutron Beamline For Studying The Magnetic Correlation Length Of A Magnetic Material At Tsing Hua Open-Pool Reactor

    NASA Astrophysics Data System (ADS)

    Su, Hui-Chia; Lee, Chih-Hao; Chang, Hsin-Ho; Wu, Yu-Han; Hu, Chih-Wei; Chang, L. J.; Ioffe, A.; Kraan, H. T.

    2010-01-01

    A new three dimensional neutron depolarization beamline was commissioning at W3 beam port of Tsing Hua Open Pool Reactor (THOR, 2 MW) located in Hsinchu, Taiwan. The beamline consists of a pair of Heusler crystals as neutron polarizer and analyzer. Two three-dimensional rotators were placed before and after the sample position. The sample chamber was enclosed in a μ-metal enclosure with a gradient field at incident and exit ports. Typically, 0.237 nm of monoenergetic neutron was selected for experiments. A flipping ratio of 23 can be obtained which corresponds to a polarization ratio of 92% of this beamline. The typical intensity is 400 n/cm2s at 1 MW operation. Magnetic correlation lengths of Ni-ferrite powders with different packing densities were measured to understand the characteristics of this beamline. The magnetic correlation lengths were observed to be 2 μm at virgin state and about 3.1 μm at remanent state. This magnetic correlation length in the virgin state is similar than the particle size. No significant change of domain size at packing density up to 60% implies that the domain wall motion is hindered by the porosity of the sample.

  4. Measurement of air refractive index fluctuation based on interferometry with two different reference cavity lengths.

    PubMed

    Chen, Qianghua; Luo, Huifu; Wang, Sumei; Wang, Feng; Chen, Xinhua

    2012-09-01

    A measurement method based on interferometry with two different reference cavity lengths is presented and applied in air refractive index measurement in which the two cavity lengths and a laser wavelength are combined to generate two wavelength equivalents of cavity. Corresponding calculation equations are derived, and the optical path configuration is designed, which is inspired by the traditional synthetic wavelength method. Theoretical analyses indicate that the measurement uncertainty of the determined index of refraction is about 2.3×10(-8), which is mainly affected by the length precision of the long vacuum cavity and the ellipticity of polarization components of the dual-frequency laser, and the range of nonambiguity is 3.0×10(-5), which is decided by the length difference of the two cavities. Experiment results show that the accuracy of air refractive index measurement is better than 5.0×10(-8) when the laboratory conditions changes slowly. The merit of the presented method is that the classical refractometry can be also used without evacuation of the gas cavity during the experiment. Furthermore, the application of the traditional synthetic wavelength method may be extended by using the wavelength equivalents of cavity, any value of which can be easily acquired by changing cavity length rather than using actual wavelengths whose number is limited. PMID:22945157

  5. Comparison of standardized clinical evaluation of wounds using ruler length by width and Scout length by width measure and Scout perimeter trace.

    PubMed

    Langemo, Diane; Spahn, James; Spahn, Thomas; Pinnamaneni, V Chowdry

    2015-03-01

    The study objective was to examine precision in wound measurement using a recently Food and Drug Administration-approved Scout (WoundVision, LLC, Indianapolis, Indiana) device to measure wound length (L) and width (W). Wound perimeter and a ruler measurement of L and W were also made. Images of 40 actual patient wounds were measured using the Scout device. All 3 techniques (length, width, perimeter) demonstrated acceptable within and between reader precision; however, the best precision was in wound perimeter measurement. PMID:25679463

  6. Bunch Length Measurements at the JLab FEL Using Coherent Transition and Synchrotron Radiation

    NASA Astrophysics Data System (ADS)

    Evtushenko, P.; Coleman, J.; Jordan, K.; Klopf, J. Michael; Neil, G.; Williams, G. P.

    2006-11-01

    The JLab FEL is routinely operated with sub-picosecond bunches. The short bunch length is important for high gain of the FEL. Coherent transition radiation has been used for the bunch length measurements for many years. This diagnostic can be used only in the pulsed beam mode. It is our goal to run the FEL with CW beam and a 74.85 MHz micropulse repetition rate, which, with the 135 pC nominal bunch charge corresponds to the beam average current of 10 mA, Hence it is very desirable to have the possibility of making bunch length measurements when running CW beam with any micropulse frequency. We use a Fourier transform infrared (FTIR) interferometer, which is essentially a Michelson interferometer, to measure the spectrum of the coherent synchrotron radiation generated in the last dipole of the magnetic bunch compressor upstream of the FEL wiggler. This noninvasive diagnostic provides bunch length measurements for CW beam operation at any micropulse frequency. We also compare the measurements made with the help of the FTIR interferometer with data obtained using the Martin-Puplett interferometer. Results of the two diagnostics agree within 15 %. Here we present a description of the experimental setup, data evaluation procedure and results of the beam measurements.

  7. Longitudinal-to-Transverse Mapping for Femtosecond Electron Bunch Length Measurement

    SciTech Connect

    Xiang, Dao; Ding, Yuantao; /SLAC

    2010-08-25

    A longitudinal-to-transverse mapping technique is proposed to measure the length and temporal profile of ultrashort electron bunches. In this scheme a special chicane and a radio-frequency deflecting cavity are used to transform the beam's longitudinal distribution into angular distribution which is further converted to transverse distribution after a parallel-to-point imaging beam line. With this technique, the temporal profile of the electron beam is exactly mapped to the transverse profile. This makes it possible to measure ultrashort electron bunch length with a resolution well beyond 1 femtosecond.

  8. Correlation of atmospheric optical turbulence and meteorological measurements

    NASA Astrophysics Data System (ADS)

    Vaucher, Gail M. Tirrell

    1989-06-01

    The correlation of meteorological events such as the jet stream, gravity waves and boundary layer circulation with the optical turbulence parameters, the transverse coherence length r sub o and the isoplanatic angle is essential for interpreting and forecasting imaging and laser systems performance. In support of the United States Air Force Relay Mirror Experiment, the Naval Postgraduate School performed a series of six site characterization measurements near Kihei, Maui, during August 1987 to July 1988. Spatial and temporal summaries of atmospheric events corresponding to the optical remote sensor data are presented using meteorological data from the National Weather Service Radiosonde Observation stations, synoptic charts, GOES-WEST infrared satellite images, and four Kihei, Maui rawinsonde datasets. To quantify the correlation between optical turbulence measurements and meteorological phenomena, four methods of calculating C square (T) from rawinsonde data were investigated. Results show that existing rawinsonde systems are inadequate for direct C square (T) calculation. However, moderate improvements in the vertical resolution, the temperature resolution and probe response time, will allow direct calculations of optical turbulence parameters from rawinsonde data.

  9. An Imaging System for Automated Characteristic Length Measurement of Debrisat Fragments

    NASA Technical Reports Server (NTRS)

    Moraguez, Mathew; Patankar, Kunal; Fitz-Coy, Norman; Liou, J.-C.; Sorge, Marlon; Cowardin, Heather; Opiela, John; Krisko, Paula H.

    2015-01-01

    The debris fragments generated by DebriSat's hypervelocity impact test are currently being processed and characterized through an effort of NASA and USAF. The debris characteristics will be used to update satellite breakup models. In particular, the physical dimensions of the debris fragments must be measured to provide characteristic lengths for use in these models. Calipers and commercial 3D scanners were considered as measurement options, but an automated imaging system was ultimately developed to measure debris fragments. By automating the entire process, the measurement results are made repeatable and the human factor associated with calipers and 3D scanning is eliminated. Unlike using calipers to measure, the imaging system obtains non-contact measurements to avoid damaging delicate fragments. Furthermore, this fully automated measurement system minimizes fragment handling, which reduces the potential for fragment damage during the characterization process. In addition, the imaging system reduces the time required to determine the characteristic length of the debris fragment. In this way, the imaging system can measure the tens of thousands of DebriSat fragments at a rate of about six minutes per fragment, compared to hours per fragment in NASA's current 3D scanning measurement approach. The imaging system utilizes a space carving algorithm to generate a 3D point cloud of the article being measured and a custom developed algorithm then extracts the characteristic length from the point cloud. This paper describes the measurement process, results, challenges, and future work of the imaging system used for automated characteristic length measurement of DebriSat fragments.

  10. Path-length measurement performance evaluation of polarizing laser interferometer prototype

    NASA Astrophysics Data System (ADS)

    Li, Yu-qiong; Luo, Zi-ren; Liu, He-shan; Dong, Yu-hui; Jin, Gang

    2015-02-01

    The space laser interferometer has been considered the most promising means for detecting gravitational waves and improving the accuracy and spatial resolution of the Earth's gravity model. An on-ground polarizing laser interferometer prototype equipped with one reference interferometer and two measurement interferometers having equal-length arms is presented in the paper. The laser interferometer prototype is designed as the demonstration of a Chinese space laser interferometer antenna in the future, of which the path-length measurement performance evaluation and preliminary noise analysis are investigated here. The results show that the path-length measurement sensitivity is better than 200 pm/Hz½ in the frequency band of 10 mHz-1 Hz, and the sensitivity of measuring the motion of a sinusoidally driven testmass is better than 100 pm within the frequency regime of 1 mHz-1 Hz. In this way, laboratory activities have demonstrated the feasibility of this prototype to measure tiny path-length fluctuations of the simulated testmass. As a next step, adopting an integrated design of optics and optical substrate to enhance the stability of the laser interferometer is being planned, and other key techniques included in the space laser interferometer such as laser pointing modulation and laser phase-locking control are to be implanted into this prototype are under consideration.

  11. Comparison of stethoscope bell and diaphragm, and of stethoscope tube length, for clinical blood pressure measurement

    PubMed Central

    Griffiths, Clive; Murray, Alan; Zheng, Dingchang

    2016-01-01

    Objective This study investigated the effect of stethoscope side and tube length on auscultatory blood pressure (BP) measurement. Methods Thirty-two healthy participants were studied. For each participant, four measurements with different combinations of stethoscope characteristics (bell or diaphragm side, standard or short tube length) were each recorded at two repeat sessions, and eight Korotkoff sound recordings were played twice on separate days to one experienced listener to determine the systolic and diastolic BPs (SBP and DBP). Analysis of variance was carried out to study the measurement repeatability between the two repeat sessions and between the two BP determinations on separate days, as well as the effects of stethoscope side and tube length. Results There was no significant paired difference between the repeat sessions and between the repeat determinations for both SBP and DBP (all P-values>0.10, except the repeat session for SBP using short tube and diaphragm). The key result was that there was a small but significantly higher DBP on using the bell in comparison with the diaphragm (0.66 mmHg, P=0.007), and a significantly higher SBP on using the short tube in comparison with the standard length (0.77 mmHg, P=0.008). Conclusion This study shows that stethoscope characteristics have only a small, although statistically significant, influence on clinical BP measurement. Although this helps understand the measurement technique and resolves questions in the published literature, the influence is not clinically significant. PMID:26741415

  12. Lifetime and diffusion length measurements on silicon material and solar cells

    NASA Technical Reports Server (NTRS)

    Othmer, S.; Chen, S. C.

    1978-01-01

    Experimental methods were evaluated for the determination of lifetime and diffusion length in silicon intentionally doped with potentially lifetime-degrading impurities found in metallurgical grade silicon, impurities which may be residual in low-cost silicon intended for use in terrestrial flat-plate arrays. Lifetime measurements were made using a steady-state photoconductivity method. Diffusion length determinations were made using short-circuit current measurements under penetrating illumination. Mutual consistency among all experimental methods was verified, but steady-state photoconductivity was found preferable to photoconductivity decay at short lifetimes and in the presence of traps. The effects of a number of impurities on lifetime in bulk material, and on diffusion length in cells fabricated from this material, were determined. Results are compared with those obtained using different techniques. General agreement was found in terms of the hierarchy of impurities which degrade the lifetime.

  13. Electron beam induced current measurements of minority carrier diffusion length in gallium nitride

    NASA Astrophysics Data System (ADS)

    Chernyak, Leonid; Osinsky, Andrei; Temkin, Henryk; Yang, J. W.; Chen, Q.; Asif Khan, M.

    1996-10-01

    Minority carrier diffusion length in epitaxial GaN layers was measured as a function of majority carrier concentration and temperature. The diffusion length of holes in n-type GaN is found to decrease from 3.4 to 1.2 μm in the doping range of 5×1015-2×1018 cm-3. The experimental results can be fitted by assuming the Einstein relation and by the experimental dependence of hole mobilities on carrier concentration. The low injection carrier lifetime of ˜15 ns, used in the fit, is largely independent of the doping level. The diffusion length, measured for ˜5×1015 and 2×1018 cm-3 dopant concentrations, shows an increase with increasing temperature, characterized by an activation energy Ea of ˜90 meV, independent of the impurity concentration.

  14. Intermediate length scale organisation in tin borophosphate glasses: new insights from high field correlation NMR.

    PubMed

    Tricot, G; Saitoh, A; Takebe, H

    2015-11-28

    The structure of tin borophosphate glasses, considered for the development of low temperature sealing glasses or anode materials for Li-batteries, has been analysed at the intermediate length scale by a combination of high field standard and advanced 1D/2D nuclear magnetic resonance techniques. The nature and extent of B/P mixing were analysed using the (11)B((31)P) dipolar heteronuclear multiple quantum coherence NMR sequence and the data interpretation allowed (i) detecting the presence and analysing the nature of the B-O-P linkages, (ii) re-interpreting the 1D (31)P spectra and (iii) extracting the proportion of P connected to borate species. Interaction between the different borate species was analysed using the (11)B double quantum-simple quantum experiment to (i) investigate the presence and nature of the B-O-B linkage, (ii) assign the different borate species observed all along the composition line and (iii) monitor the borate network formation. In addition, (119)Sn static NMR was used to investigate the evolution of the chemical environment of the tin polyhedra. Altogether, the set of data allowed determining the structural units constituting the glass network and quantifying the extent of B/P mixing. The structural data were then used to explain the non-linear and unusual evolution of the glass transition temperature. PMID:26186677

  15. The Effects of Different Pedagogical Approaches on the Learning of Length Measurement in Kindergarten

    ERIC Educational Resources Information Center

    Kotsopoulos, Donna; Makosz, Samantha; Zambrzycka, Joanna; McCarthy, Katharine

    2015-01-01

    This research investigated the effects of different pedagogical approaches on the learning of length measurement in kindergarten children. Specifically examined were the pedagogical approaches of guided instruction, center-based learning, and free exploration in the context of a play-based learning environment. This mixed design research was…

  16. ESTIMATION OF SOYBEAN ROOT LENGTH DENSITY DISTRIBUTION WITH DIRECT AND SENSOR BASED MEASUREMENTS OF CLAYPAN MORPHOLOGY

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Hydrologic and morphological properties of claypan landscapes cause variability in soybean root and shoot biomass. This study was conducted to develop predictive models of soybean root length density distribution (RLDd) using direct measurements and sensor based estimators of claypan morphology. A c...

  17. Diffusion length measurements in solar cells: An analysis and comparison of techniques

    NASA Technical Reports Server (NTRS)

    Woollam, J. A.; Khan, A. A.; Soukup, R. J.; Hermann, A. M.

    1982-01-01

    A brief review of the major techniques for measuring minority carrier diffusion lengths in solar cells is given. Emphasis is placed on comparing limits of applicability for each method, especially as applied to silicon cells or to gallium arsenide cells, including the effects of radiation damage.

  18. Correlation among DNA Linker Length, Linker Histone Concentration, and Histone Tails in Chromatin.

    PubMed

    Luque, Antoni; Ozer, Gungor; Schlick, Tamar

    2016-06-01

    Eukaryotic cells condense their genetic material in the nucleus in the form of chromatin, a macromolecular complex made of DNA and multiple proteins. The structure of chromatin is intimately connected to the regulation of all eukaryotic organisms, from amoebas to humans, but its organization remains largely unknown. The nucleosome repeat length (NRL) and the concentration of linker histones (ρLH) are two structural parameters that vary among cell types and cell cycles; the NRL is the number of DNA basepairs wound around each nucleosome core plus the number of basepairs linking successive nucleosomes. Recent studies have found a linear empirical relationship between the variation of these two properties for different cells, but its underlying mechanism remains elusive. Here we apply our established mesoscale chromatin model to explore the mechanisms responsible for this relationship, by investigating chromatin fibers as a function of NRL and ρLH combinations. We find that a threshold of linker histone concentration triggers the compaction of chromatin into well-formed 30-nm fibers; this critical value increases linearly with NRL, except for long NRLs, where the fibers remain disorganized. Remarkably, the interaction patterns between core histone tails and chromatin elements are highly sensitive to the NRL and ρLH combination, suggesting a molecular mechanism that could have a key role in regulating the structural state of the fibers in the cell. An estimate of the minimized work and volume associated with storage of chromatin fibers in the nucleus further suggests factors that could spontaneously regulate the NRL as a function of linker histone concentration. Both the tail interaction map and DNA packing considerations support the empirical NRL/ρLH relationship and offer a framework to interpret experiments for different chromatin conditions in the cell. PMID:27276249

  19. Does the orbit-averaged theory require a scale separation between periodic orbit size and perturbation correlation length?

    SciTech Connect

    Zhang, Wenlu; Lin, Zhihong

    2013-10-15

    Using the canonical perturbation theory, we show that the orbit-averaged theory only requires a time-scale separation between equilibrium and perturbed motions and verifies the widely accepted notion that orbit averaging effects greatly reduce the microturbulent transport of energetic particles in a tokamak. Therefore, a recent claim [Hauff and Jenko, Phys. Rev. Lett. 102, 075004 (2009); Jenko et al., ibid. 107, 239502 (2011)] stating that the orbit-averaged theory requires a scale separation between equilibrium orbit size and perturbation correlation length is erroneous.

  20. Focal length measurement of a microlens-array by grating shearing interferometry.

    PubMed

    Zhu, Xianchang; Hu, Song; Zhao, Lixin

    2014-10-10

    Based on grating shearing interferometry, a simple technique is introduced for focal length measurements of a microlens-array (MLA). The measurement system is composed of a He-Ne laser, condenser, collimator, the MLA under testing, a Ronchi grating, and CCD sensor. The plane wavefront from the collimator is transformed to a spherical wavefront by the MLA, while the curvature center is at the focus. Interference stripes appear at the overlap between the zero-order and first-order diffractive patterns of the grating and are detected by the CCD sensor. By analyzing the period change of stripes, the focal length is determined after the defocus of the grating is calculated. To validate the feasibility, an experiment is performed. The measurement uncertainty is discussed and measurement accuracy was determined to be 2%. PMID:25322367

  1. Measurement of leg length inequalities by Micro-Dose digital radiographs

    SciTech Connect

    Altongy, J.F.; Harcke, H.T.; Bowen, J.R.

    1987-05-01

    New technology may, in time, supersede orthoroentgenograms for measurement of leg length inequalities. Micro-Dose digital scans are a new form of radiographs that require 1% of the radiation needed to produce conventional images. The Micro-Dose digital scan and orthoroentgenogram were compared in a clinical series of 25 children and in cadaveric femoral measurements. The accuracy of digital radiographs for this application was confirmed.

  2. Measurement of high-birefringent spun fiber parameters using short-length fiber Bragg gratings.

    PubMed

    Vasiliev, S A; Przhiyalkovsky, Ya V; Gnusin, P I; Medvedkov, O I; Dianov, E M

    2016-05-30

    Spectral polarization characteristics of short-length fiber Bragg gratings UV-written in a highly-birefringent spun-fiber have been investigated. Based on the analysis of the characteristics the technique for measuring the built-in linear phase birefringence as well as the spin period in this fiber type has been suggested. In this method the birefringence dispersion is excluded and therefore the built-in linear phase birefringence can be measured with an improved accuracy. PMID:27410060

  3. Photon path length distributions for cloudy skies  oxygen A-Band measurements and model calculations

    NASA Astrophysics Data System (ADS)

    Funk, O.; Pfeilsticker, K.

    2003-03-01

    This paper addresses the statistics underlying cloudy sky radiative transfer (RT) by inspection of the distribution of the path lengths of solar photons. Recent studies indicate that this approach is promising, since it might reveal characteristics about the diffusion process underlying atmospheric radiative transfer (Pfeilsticker, 1999). Moreover, it uses an observable that is directly related to the atmospheric absorption and, therefore, of climatic relevance. However, these studies are based largely on the accuracy of the measurement of the photon path length distribution (PPD). This paper presents a refined analysis method based on high resolution spectroscopy of the oxygen A-band. The method is validated by Monte Carlo simulation atmospheric spectra. Additionally, a new method to measure the effective optical thickness of cloud layers, based on fitting the measured differential transmissions with a 1-dimensional (discrete ordinate) RT model, is presented. These methods are applied to measurements conducted during the cloud radar inter-comparison campaign CLARE’98, which supplied detailed cloud structure information, required for the further analysis. For some exemplary cases, measured path length distributions and optical thicknesses are presented and backed by detailed RT model calculations. For all cases, reasonable PPDs can be retrieved and the effects of the vertical cloud structure are found. The inferred cloud optical thicknesses are in agreement with liquid water path measurements.

  4. Infrared Spectroscope for Electron Bunch-length Measurement: Heat Sensor Parameters Analysis

    SciTech Connect

    Domgmo-Momo, Gilles; /Towson U. /SLAC

    2012-09-05

    The Linac Coherent Light Source (LCLS) is used for many experiments. Taking advantage of the free electron laser (FEL) process, scientists of various fields perform experiments of all kind. Some for example study protein folding; other experiments are more interested in the way electrons interact with the molecules before they are destroyed. These experiments among many others have very little information about the electrons x-ray produced by the FEL, except that the FEL is using bunches less than 10 femtoseconds long. To be able to interpret the data collected from those experiments, more accurate information is needed about the electron's bunch-length. Existing bunch length measurement techniques are not suitable for the measurement of such small time scales. Hence the need to design a device that will provide more precise information about the electron bunch length. This paper investigates the use of a pyreoelectric heat sensor that has a sensitivity of about 1.34 micro amps per watt for the single cell detector. Such sensitivity, added to the fact that the detector is an array sensor, makes the detector studied the primary candidate to be integrated to an infrared spectrometer designed to better measure the LCLS electron bunch length.

  5. Persistence Length of Titin from Rabbit Skeletal Muscles Measured with Scattering and Microrheology Techniques

    PubMed Central

    Di Cola, Emanuela; Waigh, Thomas A.; Trinick, John; Tskhovrebova, Larissa; Houmeida, Ahmed; Pyckhout-Hintzen, Wim; Dewhurst, Charles

    2005-01-01

    The persistence length of titin from rabbit skeletal muscles was measured using a combination of static and dynamic light scattering, and neutron small angle scattering. Values of persistence length in the range 9–16 nm were found for titin-II, which corresponds to mainly physiologically inelastic A-band part of the protein, and for a proteolytic fragment with 100-nm contour length from the physiologically elastic I-band part. The ratio of the hydrodynamic radius to the static radius of gyration indicates that the proteins obey Gaussian statistics typical of a flexible polymer in a θ-solvent. Furthermore, measurements of the flexibility as a function of temperature demonstrate that titin-II and the I-band titin fragment experience a similar denaturation process; unfolding begins at 318 K and proceeds in two stages: an initial gradual 50% change in persistence length is followed by a sharp unwinding transition at 338 K. Complementary microrheology (video particle tracking) measurements indicate that the viscoelasticity in dilute solution behaves according to the Flory/Fox model, providing a value of the radius of gyration for titin-II (63 ± 1 nm) in agreement with static light scattering and small angle neutron scattering results. PMID:15792980

  6. Correlation of intracystic pressure with cyst volume, length of common channel, biochemical changes in bile and histopathological changes in liver in choledochal cyst

    PubMed Central

    Sharma, Nitin; Bhatnagar, Veereshwar; Srinivas, M.; Agarwala, Sandeep; Singh, Manoj Kumar; Sharma, Raju

    2014-01-01

    Aims: This study was undertaken to establish correlation between intracholedochal cystic pressure (ICCP) with biochemical changes in bile, liver histology, cyst wall histology, length of common channel, and cyst volume. Materials and Methods: In this cross-sectional study, ICCP was measured after surgical access before any mobilization by direct cyst cannulation. Bile was then aspirated for biochemical estimation (bilirubin, amylase, lipase, pH, and electrolytes). Common channel length and cyst volume were determined by preoperative magnetic resonance cholangiopancreatography (MRCP). Liver histology was assessed under parenchymal, bile duct, and portal parameters. Cyst wall was examined for ulceration, inflammation, fibrosis, and metaplasia. Results: ICCP was recorded in 31 patients; mean and median ICCP were 15.64 and 14 mmHg, respectively (range = 6-30 mmHg). Cases with median ICCP < 14 had median cyst volume of 48 cc (range = 36-115) and amylase 2052 IU/L (range = 190-5052) whereas those with ICCP ≥ 15 had volume of 20 cc (range = 10-100) (P = 0.004) and amylase 36 IU/L (range = 0-2806) (P = 0.0004) suggesting inverse correlation. No significant correlation was found with bilirubin and electrolytes. ICCP directly correlated with parenchymal changes like hepatocellular damage (P = 0.002) and cholestasis (P = 0.001). It also correlated with bile duct changes. ICCP inversely correlated with cyst wall changes (P = 0.003, 0.0001, 0.023, 0.0013, respectively). High pressure cysts had normal pancreaticobiliary junction. Conclusion: High-pressure cysts tend to be smaller but have more severe backpressure changes in liver parenchyma. Low-pressure cysts have high volume and higher levels of amylase and lipase and therefore have more severe cyst wall changes. PMID:24604978

  7. Failure of the Cross Correlation Measurement Technique

    NASA Astrophysics Data System (ADS)

    McGill, Ken; Ham, Katie; Schock, Kris

    2014-03-01

    The experiment involves creating a sound wave that propagates down a pipe with 8 transducers attached at equally spaced intervals of 0.01016 meters. The numerical method used to solve for the phase component, the Cross Correlation Method, creates a high correlation value, but the speed of sound varies immensely. The method involves a Fast Fourier Transform of the collected data, which is used to find the phase of the sound wave, and the slope of the position versus time graph, which is used to calculate the speed of sound. This high correlation values shows that the data is correct, but the numerical method for analyzing the data is incorrect. We would like to thank Dr. Ken McGill for all of his time, help, and guidance with this research project. We would also like to thank Georgia College and State University for both the resources and space necessary for this experiment.

  8. Methods and apparatus for measuring a length of cable suspending a well logging tool in a borehole

    SciTech Connect

    Broding, R.A.

    1986-07-01

    A system is described for measuring depth from the mouth of a borehole to a well logging tool connected to one end of an electrically conductive cable suspended in the borehole comprising: means for applying an initial electrical time pulse signal to one end of the cable, whereby the initial electrical time pulse signal propagates the length of the cable to one end of the cable to the well logging tool connected to the other end of the cable; means for detecting at the mouth of the borehole, which is intermediate both ends of the cable, the passage of the initial electrical time pulse signal along the length of the cable; means for detecting at the mouth of the borehole a subsequent electrical time pulse propagating along the length of the cable reflected from the other end of the cable; means for determining a time interval between the detection of the initial electrical time pulse signal at the mouth of the borehole and the detection of the subsequent electrical time pulse signal at the mouth of the borehole; and means for correlating the time interval with the depth to which the well logging tool is suspended in the borehole as measured from the mouth of the borehole.

  9. Direct Comparison of Flow-FISH and qPCR as Diagnostic Tests for Telomere Length Measurement in Humans

    PubMed Central

    Gutierrez-Rodrigues, Fernanda; Santana-Lemos, Bárbara A.; Scheucher, Priscila S.; Alves-Paiva, Raquel M.; Calado, Rodrigo T.

    2014-01-01

    Telomere length measurement is an essential test for the diagnosis of telomeropathies, which are caused by excessive telomere erosion. Commonly used methods are terminal restriction fragment (TRF) analysis by Southern blot, fluorescence in situ hybridization coupled with flow cytometry (flow-FISH), and quantitative PCR (qPCR). Although these methods have been used in the clinic, they have not been comprehensively compared. Here, we directly compared the performance of flow-FISH and qPCR to measure leukocytes' telomere length of healthy individuals and patients evaluated for telomeropathies, using TRF as standard. TRF and flow-FISH showed good agreement and correlation in the analysis of healthy subjects (R2 = 0.60; p<0.0001) and patients (R2 = 0.51; p<0.0001). In contrast, the comparison between TRF and qPCR yielded modest correlation for the analysis of samples of healthy individuals (R2 = 0.35; p<0.0001) and low correlation for patients (R2 = 0.20; p = 0.001); Bland-Altman analysis showed poor agreement between the two methods for both patients and controls. Quantitative PCR and flow-FISH modestly correlated in the analysis of healthy individuals (R2 = 0.33; p<0.0001) and did not correlate in the comparison of patients' samples (R2 = 0.1, p = 0.08). Intra-assay coefficient of variation (CV) was similar for flow-FISH (10.8±7.1%) and qPCR (9.5±7.4%; p = 0.35), but the inter-assay CV was lower for flow-FISH (9.6±7.6% vs. 16±19.5%; p = 0.02). Bland-Altman analysis indicated that flow-FISH was more precise and reproducible than qPCR. Flow-FISH and qPCR were sensitive (both 100%) and specific (93% and 89%, respectively) to distinguish very short telomeres. However, qPCR sensitivity (40%) and specificity (63%) to detect telomeres below the tenth percentile were lower compared to flow-FISH (80% sensitivity and 85% specificity). In the clinical setting, flow-FISH was more accurate, reproducible, sensitive, and specific in the

  10. Morphological features and length measurements of fetal lateral ventricles at 16-25 weeks of gestation by magnetic resonance imaging.

    PubMed

    Taketani, Kaori; Yamada, Shigehito; Uwabe, Chigako; Okada, Tomohisa; Togashi, Kaori; Takakuwa, Tetsuya

    2015-05-01

    Normal growth of the lateral ventricles (LVs) was characterized three-dimensionally using magnetic resonance imaging (MRI) data from 16 human fetuses at 16-25 weeks of gestation. The LV was differentiated into four primary regions, the anterior horn, central parts, posterior horn, and inferior horn, at 16 weeks of gestation. The LV changed shape mainly by elongation and narrowing, which corresponded to the external and internal growth of the surrounding cerebrum. Six length parameters measured in the LV correlated with biparietal diameter by simple regression analysis (R(2) range, 0.56-0.93), which may be valuable for establishing a standardized prenatal protocol to assess fetal well-being and development across intrauterine periods. No correlation was found between biparietal diameter and LV volume (R(2) = 0.13). PMID:25059317

  11. Do male secondary sexual characters correlate with testis size and sperm length in the small hairy maggot blowfly?

    PubMed

    Jones, Stephanie D; Wallman, James F; Byrne, Phillip G

    2015-12-01

    The phenotype-linked fertility hypothesis proposes that secondary sexual characters (SSCs) advertise a male's fertility to prospective mates. However, findings from empirical studies attempting to test this hypothesis are often ambivalent or even contradictory, and few studies have simultaneously evaluated how both morphological and behavioural SSCs relate to ejaculate characteristics. Males of the small hairy maggot blowfly, Chrysomya varipes, possess conspicuous foreleg ornaments and display highly stereotyped courtship behaviour. These traits are favoured by females during pre-copulatory mate choice, but it remains unknown whether they correlate with post-copulatory traits expected to influence male fertility. The aim of this study was to investigate whether male courtship and ornamentation correlate with testis size and sperm length in C. varipes. We found that males investing more in courtship had bigger testes, and males with more extensive foreleg ornamentation released sperm with longer tails. Based on the assumption that larger testes enable males to produce more sperm, and that sperm with longer tails have greater propulsive force, our findings suggest that more vigorous and more ornamented males may be more fertile. These findings lend support to the phenotype-linked fertility hypothesis. However, a complete test of this hypothesis will require evaluating whether testis size and sperm length influence male fertilisation ability, as well as female fecundity and/or fertility. PMID:26297128

  12. Traveling length and minimal traveling time for flow through percolation networks with long-range spatial correlations

    NASA Astrophysics Data System (ADS)

    Araújo, A. D.; Moreira, A. A.; Makse, H. A.; Stanley, H. E.; Andrade, J. S.

    2002-10-01

    We study the distributions of traveling length l and minimal traveling time tmin through two-dimensional percolation porous media characterized by long-range spatial correlations. We model the dynamics of fluid displacement by the convective movement of tracer particles driven by a pressure difference between two fixed sites (``wells'') separated by Euclidean distance r. For strongly correlated pore networks at criticality, we find that the probability distribution functions P(l) and P(tmin) follow the same scaling ansatz originally proposed for the uncorrelated case, but with quite different scaling exponents. We relate these changes in dynamical behavior to the main morphological difference between correlated and uncorrelated clusters, namely, the compactness of their backbones. Our simulations reveal that the dynamical scaling exponents dl and dt for correlated geometries take values intermediate between the uncorrelated and homogeneous limiting cases, where l*~rdl and t*min~rdt, and l* and t*min are the most probable values of l and tmin, respectively.

  13. Statistical processing and convergence of finite-record-length time-series measurements from turbulent flows

    NASA Astrophysics Data System (ADS)

    Papageorge, Michael; Sutton, Jeffrey A.

    2016-08-01

    In this manuscript, we investigate the statistical convergence of turbulent flow statistics from finite-record-length time-series measurements. Analytical solutions of the convergence rate of the mean, variance, and autocorrelation function as a function of record length are presented based on using mean-squared error analysis and the consideration of turbulent flows as random processes. Experimental assessment of the statistical convergence theory is presented using 20-kHz laser Rayleigh scattering measurements of a conserved scalar (ξ) in a turbulent free jet. Excellent agreement between experiments and theory is noted, providing validation of the statistical convergence analysis. To the authors' knowledge, this is the first reported assessment and verification of statistical convergence theory as applied to turbulent flows. The verified theory provides a practitioner a method for a priori determining the necessary temporal record length for a desired statistical accuracy or conversely, accurately estimating the uncertainty of a measurement for a given temporal record length. Furthermore, we propose a new hybrid "multi-burst" data processing scheme based on combined independent ensemble and time-series statistics targeted for shorter-duration time-series measurements. The new methodology is based on taking the ensemble mean of derived statistical moments from many individual finite-duration time-series measurements. This approach is used to systematically converge toward the "expected" value of any statistical moment at a rate of √ M, where M is the number of individual time-series measurements. The proposed multi-burst methodology is assessed experimentally, and excellent agreement between measurements and theory is observed. A key outcome of the implementation of the multi-burst processing method is noted in the estimation of the autocorrelation function. Specifically, an unbiased estimator of the autocorrelation function can be used with much less

  14. Connection between measurement disturbance relation and multipartite quantum correlation

    NASA Astrophysics Data System (ADS)

    Li, Jun-Li; Du, Kun; Qiao, Cong-Feng

    2015-01-01

    It is found that the measurement disturbance relation (MDR) determines the strength of quantum correlation and hence is one of the essential facets of the nature of quantum nonlocality. In reverse, the exact form of MDR may be ascertained through measuring the correlation function. To this aim, an optical experimental scheme is proposed. Moreover, by virtue of the correlation function, we find that the quantum entanglement, the quantum nonlocality, and the uncertainty principle can be explicitly correlated.

  15. Hot Electron Attenuation Length Measurements of Cu and Ag using BEEM

    NASA Astrophysics Data System (ADS)

    Garramone, John; Abel, Joseph; Sitnitsky, Ilona; Zhao, Lai; Appelbaum, Ian; Labella, Vincent

    2010-03-01

    33.4˜2.9 nm 1.0 eV Understanding electron transport and scattering in nanoscale Cu and Ag structures is important for modern integrated circuit technology and futuristic applications such as spintronics and hydrogen sensing footnotetextHuang et al., Rev. Lett. 99 177209 (2007)^,footnotetextNienhaus et at., Appl. Phys. Lett. 74 4046 (1999). In this study we will report on hot electron attenuation length measurements of nanometer thick films of Cu and Ag on the Si substrate utilizing ballistic electron emission microscopy (BEEM). BEEM is a three terminal scanning tunneling microcopy (STM) based technique where electrons are injected from a STM tip into a grounded metal base of a Schottky diode. The electrons that transverse the metal overlayer and surmount the Schottky barrier are measured as the BEEM current by a backside contact to the semiconductor. The attenuation length is extracted by measuring the falloff in BEEM current as a function of metal film thickness. The hot electron attenuation length for Cu of is measured at a tip bias of and a temperature of 80 K. Results for Ag will also be presented as well as models used to extract the relative contribution of elastic and inelastic electron scattering in the metal films as a function of electron energy.

  16. Adherence to Criteria for Transvaginal Ultrasound Imaging and Measurement of Cervical Length

    PubMed Central

    Iams, JD; Grobman, WA; Lozitska, A; Spong, CY; Saade, G; Mercer, BM; Tita, AN; Rouse, DJ; Sorokin, Y; Wapner, RJ; Leveno, KJ; Esplin, MS; Tolosa, JE; Thorp, JM; Caritis, SN; Van Dorsten, JP

    2014-01-01

    Background Adherence to published criteria for transvaginal imaging and measurement of cervical length is uncertain. We sought to assess adherence by evaluating images submitted to certify research sonographers for participation in a clinical trial. Study Design We reviewed qualifying test results of sonographers seeking certification to image and measure cervical length in a clinical trial. Participating sonographers were required to access training materials and submit 15 images, three each from five pregnant women not enrolled in the trial. One of two sonologists reviewed all qualifying images. We recorded the proportion of images that did not meet standard criteria (excess compression, landmarks not seen, improper image size, or full maternal bladder) and the proportion in which the cervical length was measured incorrectly. Failure for a given patient was defined as more than one unacceptable image, or more than two acceptable images with incorrect caliper placement or erroneous choice of the “shortest best” cervical length. Certification required satisfactory images and cervical length measurement from four or more patients. Results 327 sonographers submitted 4905 images. 271 sonographers (83%) were certified on the first, 41 (13%) on the second, and 2 (0.6%) on the third submission. 13 never achieved certification. Of 314 who passed, 196 submitted 15 acceptable images that were appropriately measured for all five women. There were 1277 deficient images: 493 were acceptable but incorrectly measured images from sonographers who passed certification because mis-measurement occurred no more than twice. Of 784 deficient images submitted by sonographers who failed the certification, 471 were rejected because of improper measurement (caliper placement and/or failure to identify the shortest best image), and 313 because of failure to obtain a satisfactory image (excessive compression, required landmarks not visible, incorrect image size, brief examination, and

  17. Dislocation densities and lengths in solid 4He from elasticity measurements

    NASA Astrophysics Data System (ADS)

    Haziot, Ariel; Fefferman, Andrew D.; Beamish, John R.; Balibar, Sébastien

    2013-02-01

    Measurements on solid 4He show large softening of the shear modulus due to dislocations, behavior which has been described as giant plasticity. Dislocation networks may also be responsible for the unusual behavior seen in torsional oscillator and flow experiments. However, previous estimates of dislocation densities vary by many orders of magnitude, even in single crystals grown under similar conditions. By measuring the temperature and frequency dependencies of the elastic dissipation, we have determined dislocation densities and network lengths in 4He single crystals, both in coexistence with liquid and at higher pressures, and in polycrystals grown at constant density. In all cases, dislocation lengths are much longer and the networks are less connected than previous estimates. Even in polycrystals, the dislocation network is far too sparse to explain the torsional oscillator results in terms of superfluidity in a dislocation network.

  18. Diffusion length measurements of thin GaAs solar cells by means of energetic electrons

    NASA Technical Reports Server (NTRS)

    Vonross, O.

    1980-01-01

    A calculation of the short circuit current density (j sub sc) of a thin GaAs solar cell induced by fast electrons is presented. It is shown that in spite of the disparity in thickness between the N-type portion of the junction and the P-type portion of the junction, the measurement of the bulk diffusion length L sub p of the N-type part of the junction is seriously hampered due to the presence of a sizable contribution to the j sub sc from the P-type region of the junction. Corrections of up to 50% had to be made in order to interpret the data correctly. Since these corrections were not amenable to direct measurements it is concluded that the electron beam method for the determination of the bulk minority carrier diffusion length, which works so well for Si solar cells, is a poor method when applied to thin GaAs cells.

  19. Influence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies

    PubMed Central

    Raschenberger, Julia; Lamina, Claudia; Haun, Margot; Kollerits, Barbara; Coassin, Stefan; Boes, Eva; Kedenko, Ludmilla; Köttgen, Anna; Kronenberg, Florian

    2016-01-01

    Measurement of telomere length is widely used in epidemiologic studies. Insufficient standardization of the measurements processes has, however, complicated the comparison of results between studies. We aimed to investigate whether DNA extraction methods have an influence on measured values of relative telomere length (RTL) and whether this has consequences for epidemiological studies. We performed four experiments with RTL measurement in quadruplicate by qPCR using DNA extracted with different methods: 1) a standardized validation experiment including three extraction methods (magnetic-particle-method EZ1, salting-out-method INV, phenol-chloroform-isoamyl-alcohol PCI) each in the same 20 samples demonstrated pronounced differences in RTL with lowest values with EZ1 followed by INV and PCI-isolated DNA; 2) a comparison of 307 samples from an epidemiological study showing EZ1-measurements 40% lower than INV-measurements; 3) a matching-approach of two similar non-diseased control groups including 143 pairs of subjects revealed significantly shorter RTL in EZ1 than INV-extracted DNA (0.844 ± 0.157 vs. 1.357 ± 0.242); 4) an association analysis of RTL with prevalent cardiovascular disease detected a stronger association with INV than with EZ1-extracted DNA. In summary, DNA extraction methods have a pronounced influence on the measured RTL-values. This might result in spurious or lost associations in epidemiological studies under certain circumstances. PMID:27138987

  20. Influence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies.

    PubMed

    Raschenberger, Julia; Lamina, Claudia; Haun, Margot; Kollerits, Barbara; Coassin, Stefan; Boes, Eva; Kedenko, Ludmilla; Köttgen, Anna; Kronenberg, Florian

    2016-01-01

    Measurement of telomere length is widely used in epidemiologic studies. Insufficient standardization of the measurements processes has, however, complicated the comparison of results between studies. We aimed to investigate whether DNA extraction methods have an influence on measured values of relative telomere length (RTL) and whether this has consequences for epidemiological studies. We performed four experiments with RTL measurement in quadruplicate by qPCR using DNA extracted with different methods: 1) a standardized validation experiment including three extraction methods (magnetic-particle-method EZ1, salting-out-method INV, phenol-chloroform-isoamyl-alcohol PCI) each in the same 20 samples demonstrated pronounced differences in RTL with lowest values with EZ1 followed by INV and PCI-isolated DNA; 2) a comparison of 307 samples from an epidemiological study showing EZ1-measurements 40% lower than INV-measurements; 3) a matching-approach of two similar non-diseased control groups including 143 pairs of subjects revealed significantly shorter RTL in EZ1 than INV-extracted DNA (0.844 ± 0.157 vs. 1.357 ± 0.242); 4) an association analysis of RTL with prevalent cardiovascular disease detected a stronger association with INV than with EZ1-extracted DNA. In summary, DNA extraction methods have a pronounced influence on the measured RTL-values. This might result in spurious or lost associations in epidemiological studies under certain circumstances. PMID:27138987

  1. Integrated measurements of acoustical and optical thin layers II: Horizontal length scales

    NASA Astrophysics Data System (ADS)

    Moline, Mark A.; Benoit-Bird, Kelly J.; Robbins, Ian C.; Schroth-Miller, Maddie; Waluk, Chad M.; Zelenke, Brian

    2010-01-01

    The degree of layered organization of planktonic organisms in coastal systems impacts trophic interactions, the vertical availability of nutrients, and many biological rate processes. While there is reasonable characterization of the vertical structure of these phenomena, the extent and horizontal length scale of variation has rarely been addressed. Here we extend the examination of the vertical scale in the first paper of the series to the horizontal scale with combined shipboard acoustic measurements and bio-optic measurements taken on an autonomous underwater vehicle. Measurements were made in Monterey Bay, CA from 2002 to 2008 for the bio-optical parameters and during 2006 for acoustic scattering measurements. The combined data set was used to evaluate the horizontal decorrelation length scales of the bio-optical and acoustic scattering layers themselves. Because biological layers are often decoupled from the physical structure of the water column, assessment of the variance within identified layers was appropriate. This differs from other studies in that physical parameters were not used as a basis for the layer definition. There was a significant diel pattern to the decorrelation length scale for acoustic layers with the more abundant nighttime layers showing less horizontal variability despite their smaller horizontal extent. A significant decrease in the decorrelation length scale was found in bio-optical parameters over six years of study, coinciding with a documented shift in the plankton community. Results highlight the importance of considering plankton behavior and time of day with respect to scale when studying layers, and the challenges of sampling these phenomena.

  2. Measurement of atmospheric coherence length with differential movement of the image sensor

    NASA Astrophysics Data System (ADS)

    Jia, Yu-gang; Tong, Shou-feng

    2013-08-01

    This paper gives the introduction about a new measuring device which is to measure th e atmospheric coherence length by using the differential movement principle.The system can observe the edge of the sun in the day time, and also observe planets at night. This system can measure the atmospheric coherence length in both horizontal and slant directions. The measurement in the day time requests the assistance of the attenuator and beacon beam of the atmospheric coherence length in the direction of the slant path.The working principle is the laser beam scattered by atmospheric turbulence through into the receiving optical system. Because the receiving system which is consists of two completely symmetrical telephoto optical system. Therefore,two optical channels in turbulence device are completely identical. After passing through the optical channels, the beam focusing is finished. By adjusting the optical system manually or automatically, two light point images can be formed on the photosensitive element of the CCD. Atmospheric turbulence can cause phase fluctuation of wave front. After aggregation by the receiving lens, The photosensitive element of CCD can collect the relative jitter of the two imaging optical centroid positions we require, and researchers can obtain relative changes from the two centroid positions by the calculations of computer software, as the result, the atmospheric coherence length is obtained. By means of the simulation of the optical system and the imaging quality optimization by Code V, researchers can rather achieve transfer function diagram, the circle of confusion value in different views and energy distribution. From above, researchers can examine whether the optical system is being qualified, or the method is leading to a better observation effect. At end of this dissertation, the limitations of this system will be analyzed, and the improvement methods and suggestions will be provided.

  3. Depth-resolved photothermal optical coherence tomography by local optical path length change measurement (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Makita, Shuichi; Hong, Young-Joo; Li, En; Yasuno, Yoshiaki

    2016-03-01

    Photothermal OCT has been emerged to contrast absorbers in biological tissues. The tissues response to photothermal excitation as change of thermal strain and refractive index. To resolve the depth of absorption agents, the measurements of the local thermal strain change and local refractive index change due to photothermal effect is required. In this study, we developed photothermal OCT for depth-resolved absorption contrast imaging. The phase-resolved OCT can measure the axial strain change and local refractive index change as local optical path length change. A swept-source OCT system is used with a wavelength swept laser at 1310 nm with a scanning rate of 50 kHz. The sensitivity of 110 dB is achieved. At the sample arm, the excitation beam from a fiber-coupled laser diode of 406 nm wavelength is combined with the OCT probe beam co-linearly. The slowly modulated excitation beam around 300 Hz illuminate biological tissues. M-mode scan is applied during one-period modulation duration. The local optical path length change is measured by temporal and axial phase difference. The theoretical prediction of the photothermal response is derived and in good agreement with experimental results. In the case of slow modulation, the delay of photothermal response can be neglected. The local path length changes are averaged over the half period of the excitation modulation, and then demodulated. This method exhibits 3-dB gain in the sensitivity of the local optical path length change measurement over the direct Fourier transform method. In vivo human skin imaging of endogenous absorption agent will be demonstrated.

  4. Ultrasonic measurement of stress in railroad wheels and in long lengths of welded rail

    NASA Technical Reports Server (NTRS)

    Clotfelter, W. N.; Risch, E. R.

    1974-01-01

    The failure of high speed emergency braking is discussed for railroad wheels and track. It is shown that high compressive residual stresses exist in the rims of new wheels which generate excessive heat, reducing the stress levels. Thermal stresses that build up in continuous lengths of welded track are reported and nondestructive methods of measuring stresses in thick steel are presented for identification, replacement, or adjustment before hazardous failures occur.

  5. Absolute Bunch Length Measurements at the ALS by Incoherent Synchrotron Radiation Fluctuation Analysis

    SciTech Connect

    Filippetto, D.; Sannibale, F.; Zolotorev, Max Samuil; Stupakov, G.V.; /SLAC

    2008-01-24

    By analyzing the pulse to pulse intensity fluctuations of the radiation emitted by a charge particle in the incoherent part of the spectrum, it is possible to extract information about the spatial distribution of the beam. At the Advanced Light Source (ALS) of the Lawrence Berkeley National Laboratory, we have developed and tested a simple scheme based on this principle that allows for the absolute measurement of the bunch length. A description of the method and the experimental results are presented.

  6. Magnetic Field-line Length and Twist Distributions within Interplanetary Flux Fopes from Wind Spacecraft Measurements

    NASA Astrophysics Data System (ADS)

    Hu, Q.; Qiu, J.; Krucker, S.; Wang, L.; Wang, B.; Chen, Y.; Moestl, C.

    2014-12-01

    We report on the detailed and systematic study of field-line twist and length distributions within magnetic flux ropes embedded in Interplanetary Coronal Mass Ejections (ICMEs). In particular we will utilize energetic electron burst observations at 1 AU together with associated type III radio emissions detected by the Wind spacecraft to provide unique measurements of magnetic field-line lengths within selected ICME events. These direct measurements will be compared with flux-rope model calculations to help assess the fidelity of different models and to provide diagnostics of internal structures. The Grad-Shafranov reconstruction method will be utilized together with a constant-twist nonlinear force-free (Gold-Hoyle) flux rope model and the commonly known Lundquist (linear force-free) model to reveal the close relation between the field-line twist and length in cylindrical flux ropes, based on in-situ Wind spacecraft magnetic field and plasma measurements. We show that our initial analysis of field-line twist indicates clear deviation from the Lundquist model, but better consistency with the Gold-Hoyle model. We will also discuss the implications of our analysis of flux-rope structures on the origination and evolution processes in their corresponding solar source regions.

  7. Isotopic fractionation in proteins as a measure of hydrogen bond length

    NASA Astrophysics Data System (ADS)

    McKenzie, Ross H.; Athokpam, Bijyalaxmi; Ramesh, Sai G.

    2015-07-01

    If a deuterated molecule containing strong intramolecular hydrogen bonds is placed in a hydrogenated solvent, it may preferentially exchange deuterium for hydrogen. This preference is due to the difference between the vibrational zero-point energy for hydrogen and deuterium. It is found that the associated fractionation factor Φ is correlated with the strength of the intramolecular hydrogen bonds. This correlation has been used to determine the length of the H-bonds (donor-acceptor separation) in a diverse range of enzymes and has been argued to support the existence of short low-barrier H-bonds. Starting with a potential energy surface based on a simple diabatic state model for H-bonds, we calculate Φ as a function of the proton donor-acceptor distance R. For numerical results, we use a parameterization of the model for symmetric O-H⋯O bonds [R. H. McKenzie, Chem. Phys. Lett. 535, 196 (2012)]. We consider the relative contributions of the O-H stretch vibration, O-H bend vibrations (both in plane and out of plane), tunneling splitting effects at finite temperature, and the secondary geometric isotope effect. We compare our total Φ as a function of R with NMR experimental results for enzymes, and in particular with an earlier model parametrization Φ(R), used previously to determine bond lengths.

  8. Isotopic fractionation in proteins as a measure of hydrogen bond length.

    PubMed

    McKenzie, Ross H; Athokpam, Bijyalaxmi; Ramesh, Sai G

    2015-07-28

    If a deuterated molecule containing strong intramolecular hydrogen bonds is placed in a hydrogenated solvent, it may preferentially exchange deuterium for hydrogen. This preference is due to the difference between the vibrational zero-point energy for hydrogen and deuterium. It is found that the associated fractionation factor Φ is correlated with the strength of the intramolecular hydrogen bonds. This correlation has been used to determine the length of the H-bonds (donor-acceptor separation) in a diverse range of enzymes and has been argued to support the existence of short low-barrier H-bonds. Starting with a potential energy surface based on a simple diabatic state model for H-bonds, we calculate Φ as a function of the proton donor-acceptor distance R. For numerical results, we use a parameterization of the model for symmetric O-H⋯O bonds [R. H. McKenzie, Chem. Phys. Lett. 535, 196 (2012)]. We consider the relative contributions of the O-H stretch vibration, O-H bend vibrations (both in plane and out of plane), tunneling splitting effects at finite temperature, and the secondary geometric isotope effect. We compare our total Φ as a function of R with NMR experimental results for enzymes, and in particular with an earlier model parametrization Φ(R), used previously to determine bond lengths. PMID:26233131

  9. Isotopic fractionation in proteins as a measure of hydrogen bond length

    SciTech Connect

    McKenzie, Ross H.; Athokpam, Bijyalaxmi; Ramesh, Sai G.

    2015-07-28

    If a deuterated molecule containing strong intramolecular hydrogen bonds is placed in a hydrogenated solvent, it may preferentially exchange deuterium for hydrogen. This preference is due to the difference between the vibrational zero-point energy for hydrogen and deuterium. It is found that the associated fractionation factor Φ is correlated with the strength of the intramolecular hydrogen bonds. This correlation has been used to determine the length of the H-bonds (donor-acceptor separation) in a diverse range of enzymes and has been argued to support the existence of short low-barrier H-bonds. Starting with a potential energy surface based on a simple diabatic state model for H-bonds, we calculate Φ as a function of the proton donor-acceptor distance R. For numerical results, we use a parameterization of the model for symmetric O–H⋯O bonds [R. H. McKenzie, Chem. Phys. Lett. 535, 196 (2012)]. We consider the relative contributions of the O–H stretch vibration, O–H bend vibrations (both in plane and out of plane), tunneling splitting effects at finite temperature, and the secondary geometric isotope effect. We compare our total Φ as a function of R with NMR experimental results for enzymes, and in particular with an earlier model parametrization Φ(R), used previously to determine bond lengths.

  10. Edge Length and Surface Area of a Blank: Experimental Assessment of Measures, Size Predictions and Utility

    PubMed Central

    Dogandžić, Tamara; Braun, David R.; McPherron, Shannon P.

    2015-01-01

    Blank size and form represent one of the main sources of variation in lithic assemblages. They reflect economic properties of blanks and factors such as efficiency and use life. These properties require reliable measures of size, namely edge length and surface area. These measures, however, are not easily captured with calipers. Most attempts to quantify these features employ estimates; however, the efficacy of these estimations for measuring critical features such as blank surface area and edge length has never been properly evaluated. In addition, these parameters are even more difficult to acquire for retouched implements as their original size and hence indication of their previous utility have been lost. It has been suggested, in controlled experimental conditions, that two platform variables, platform thickness and exterior platform angle, are crucial in determining blank size and shape meaning that knappers can control the interaction between size and efficiency by selecting specific core angles and controlling where fracture is initiated. The robustness of these models has rarely been tested and confirmed in context other than controlled experiments. In this paper, we evaluate which currently employed caliper measurement methods result in the highest accuracy of size estimations of blanks, and we evaluate how platform variables can be used to indirectly infer aspects of size on retouched artifacts. Furthermore, we investigate measures of different platform management strategies that control the shape and size of artifacts. To investigate these questions, we created an experimental lithic assemblage, we digitized images to calculate 2D surface area and edge length, which are used as a point of comparison for the caliper measurements and additional analyses. The analysis of aspects of size determinations and the utility of blanks contributes to our understanding of the technological strategies of prehistoric knappers and what economic decisions they made

  11. Bilateral step length estimation using a single inertial measurement unit attached to the pelvis

    PubMed Central

    2012-01-01

    Background The estimation of the spatio-temporal gait parameters is of primary importance in both physical activity monitoring and clinical contexts. A method for estimating step length bilaterally, during level walking, using a single inertial measurement unit (IMU) attached to the pelvis is proposed. In contrast to previous studies, based either on a simplified representation of the human gait mechanics or on a general linear regressive model, the proposed method estimates the step length directly from the integration of the acceleration along the direction of progression. Methods The IMU was placed at pelvis level fixed to the subject's belt on the right side. The method was validated using measurements from a stereo-photogrammetric system as a gold standard on nine subjects walking ten laps along a closed loop track of about 25 m, varying their speed. For each loop, only the IMU data recorded in a 4 m long portion of the track included in the calibrated volume of the SP system, were used for the analysis. The method takes advantage of the cyclic nature of gait and it requires an accurate determination of the foot contact instances. A combination of a Kalman filter and of an optimally filtered direct and reverse integration applied to the IMU signals formed a single novel method (Kalman and Optimally filtered Step length Estimation - KOSE method). A correction of the IMU displacement due to the pelvic rotation occurring in gait was implemented to estimate the step length and the traversed distance. Results The step length was estimated for all subjects with less than 3% error. Traversed distance was assessed with less than 2% error. Conclusions The proposed method provided estimates of step length and traversed distance more accurate than any other method applied to measurements obtained from a single IMU that can be found in the literature. In healthy subjects, it is reasonable to expect that, errors in traversed distance estimation during daily monitoring

  12. Scattering length measurements from radiative pion capture and neutron-deuteron breakup

    SciTech Connect

    Gibson, B.F.; Tornow, W. |; Carman, T.S.

    1997-07-01

    The neutron-neutron and neutron-proton {sup 1}S{sub 0} scattering lengths a{sub nn} and a{sub np}, respectively, were determined simultaneously from the neutron-deuteron breakup reaction. Their comparison with the recommended values obtained from two body reactions gives a measure of the importance of three-nucleon force effects in the three-nucleon continuum. In order to check on the result obtained for a{sub nn} from the two-body {pi}{sup {minus}}-d capture reaction, a new measurement was performed at LANL. Preliminary results of the three experiments are given.

  13. d + Au hadron correlation measurements at PHENIX

    SciTech Connect

    Anne M. Sickles

    2014-05-13

    In these proceedings, we discuss recent results from d + Au collisions in PHENIX ridge related measurements and their possible hydrodynamic origin. We present the v2 at midrapidity and measurements of the pseudorapidity dependence of the ridge, distinguishing between the d-going and Au-going directions. We investigate the possible geometrical origin by comparing v2 in d + Au to that in p + Pb, Au + Au and Pb + Pb collisions. Future plans to clarify the role of geometry in small collision systems at RHIC are discussed.

  14. Attribute-Based Time Series Cross-Correlation Measures

    NASA Astrophysics Data System (ADS)

    Cooper, G. R. J.

    2016-05-01

    Datasets are usually compared using cross-correlation, often using a moving window to calculate the correlation as a function of time or space. However, signals can be considered as being composed of sinusoids which possess amplitudes, frequencies and phases. All these three attributes can be computed at each point in time, and then used as the basis of a cross-correlation method. By using all the three measures of correlation together, their individual disadvantages can be minimised. By combining these measures with the continuous wavelet transform, information on the correlation as a function of wavelength can be obtained.

  15. High precision optical cavity length and width measurements using double modulation.

    PubMed

    Staley, A; Hoak, D; Effler, A; Izumi, K; Dwyer, S; Kawabe, K; King, E J; Rakhmanov, M; Savage, R L; Sigg, D

    2015-07-27

    We use doubly phase modulated light to measure both the length and the linewidth of an optical resonator with high precision. The first modulation is at RF frequencies and is set near a multiple of the free spectral range, whereas the second modulation is at audio frequencies to eliminate offset errors at DC. The light in transmission or in reflection of the optical resonator is demodulated while sweeping the RF frequency over the optical resonance. We derive expressions for the demodulated power in transmission, and show that the zero crossings of the demodulated signal in transmission serve as a precise measure of the cavity linewidth at half maximum intensity. We demonstrate the technique on two resonant cavities, with lengths 16 m and a 4 km, and achieve an absolute length accuracy as low as 70 ppb. The cavity width for the 16 m cavity was determined with an accuracy of approximately 6000 ppm. Through an analysis of the systematic errors we show that this result could be substantially improved with the reduction of technical sources of uncertainty. PMID:26367601

  16. Round-Trip System Available to Measure Path Length Variation in Korea VLBI System for Geodesy

    NASA Technical Reports Server (NTRS)

    Oh, Hongjong; Kondo, Tetsuro; Lee, Jinoo; Kim, Tuhwan; Kim, Myungho; Kim, Suchul; Park, Jinsik; Ju, Hyunhee

    2010-01-01

    The construction project of Korea Geodetic VLBI officially started in October 2008. The construction of all systems will be completed by the end of 2011. The project was named Korea VLBI system for Geodesy (KVG), and its main purpose is to maintain the Korea Geodetic Datum. In case of the KVG system, an observation room with an H-maser frequency standard is located in a building separated from the antenna by several tens of meters. Therefore KVG system will adopt a so-called round-trip system to transmit reference signals to the antenna with reduction of the effect of path length variations. KVG s round-trip system is designed not only to use either metal or optical fiber cables, but also to measure path length variations directly. We present this unique round trip system for KVG.

  17. Force-dependent persistence length of DNA-intercalator complexes measured in single molecule stretching experiments.

    PubMed

    Bazoni, R F; Lima, C H M; Ramos, E B; Rocha, M S

    2015-06-01

    By using optical tweezers with an adjustable trap stiffness, we have performed systematic single molecule stretching experiments with two types of DNA-intercalator complexes, in order to investigate the effects of the maximum applied forces on the mechanical response of such complexes. We have explicitly shown that even in the low-force entropic regime the persistence length of the DNA-intercalator complexes is strongly force-dependent, although such behavior is not exhibited by bare DNA molecules. We discuss the possible physicochemical effects that can lead to such results. In particular, we propose that the stretching force can promote partial denaturation on the highly distorted double-helix of the DNA-intercalator complexes, which interfere strongly in the measured values of the persistence length. PMID:25913936

  18. Ultracold mixtures of metastable He and Rb: Scattering lengths from ab initio calculations and thermalization measurements

    NASA Astrophysics Data System (ADS)

    Knoop, S.; Żuchowski, P. S.; KÈ©dziera, D.; Mentel, Ł.; Puchalski, M.; Mishra, H. P.; Flores, A. S.; Vassen, W.

    2014-08-01

    We have investigated the ultracold interspecies scattering properties of metastable triplet He and Rb. We performed state-of-the-art ab initio calculations of the relevant interaction potential, and measured the interspecies elastic cross section for an ultracold mixture of metastable triplet He4 and Rb87 in a quadrupole magnetic trap at a temperature of 0.5 mK. Our combined theoretical and experimental study gives an interspecies scattering length a4+87=+17-4+1a0, which prior to this work was unknown. More general, our work shows the possibility of obtaining accurate scattering lengths using ab initio calculations for a system containing a heavy, many-electron atom, such as Rb.

  19. Study on the impact of fiber length on the correlation of separation and orientation in flow molded glass fiber-reinforced plastic composites.

    PubMed

    Kim, Jin-Woo; Lee, Dong-Gi

    2014-10-01

    During the compression molding of fiber-reinforced plastic composites, there are two issues: one is separation of fiber and matrix because of the different flow state and fiber orientation. Due to separation and orientation, moldings become nonhomogeneous, and show anisotropy. Therefore, separation and orientation should be closely corresponded to molding condition and fiber structure. If fiber shows strong agglomeration, it increases the separation, but fiber orientation will be limited. That is, separation and orientation of fiber is closely related, and the relationship should be clearly defined. In this study, fiber content and length is varied for stacked laminates, and primary sheet is fabricated with thermal compression press. Primary sheet is heated and molded with 30-ton hydraulic press. Nonhomogeneity, one of indicators for separation, is measured from one-dimensional rectangular plate after compression. Orientation function is calculated using X-ray image on moldings and image scanner for processing imagery data. From the correlation between the separation and the orientation of fiber and matrix, the correlation coefficient is defined, and the impact of fiber length on the coefficient is evaluated. PMID:25942851

  20. Measuring correlations between non-stationary series with DCCA coefficient

    NASA Astrophysics Data System (ADS)

    Kristoufek, Ladislav

    2014-05-01

    In this short report, we investigate the ability of the DCCA coefficient to measure correlation level between non-stationary series. Based on a wide Monte Carlo simulation study, we show that the DCCA coefficient can estimate the correlation coefficient accurately regardless the strength of non-stationarity (measured by the fractional differencing parameter d). For a comparison, we also report the results for the standard Pearson correlation coefficient. The DCCA coefficient dominates the Pearson coefficient for non-stationary series.

  1. Comparison of the measurement standards of the length unit in the field of roundness deviations measurements

    NASA Astrophysics Data System (ADS)

    Lysenko, V. G.; Kupko, V. S.; Makarevich, V. B.

    2016-01-01

    A trilateral comparison has been performed in the subject field of roundness measurement. The comparison was pilot by VNIIMS, Russia and took place between February 2014 and August 2014. The circulated standards were a roundness transfer standard in the form of a glass hemisphere and a magnification standard often referred to as a 'Flick' standard. Data from the roundness standard were processed using a Gaussian filter and a bandpass up to 50 undulations per revolution to provide a measured value of Roundness Deviation (RONt). For the magnification standard, data were also filtered and the fitted element was the circumscribed circle together with the deviation of the valleys (RONv). The results of comparisons show the correspondence of measurement uncertainties to the declared values and the compared measurement standards are equivalent. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCL, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  2. Development of a scanning tunneling potentiometry system for measurement of electronic transport at short length scales

    NASA Astrophysics Data System (ADS)

    Rozler, Michael

    It is clear that complete understanding of macroscopic properties of materials is impossible without a thorough knowledge of behavior at the smallest length scales. While the past 25 years have witnessed major advances in a variety of techniques that probe the nanoscale properties of matter, electrical transport measurements -- the heart of condensed matter research -- have lagged behind, never progressing beyond bulk measurements. This thesis describes a scanning tunneling potentiometry (STP) system developed to simultaneously map the transport-related electrochemical potential distribution of a biased sample along with its surface topography, extending electronic transport measurements to the nanoscale. Combining a novel sample biasing technique with a continuous current-nulling feedback scheme pushes the noise performance of the measurement to its fundamental limit - the Johnson noise of the STM tunnel junction. The resulting 130 nV voltage sensitivity allows us to spatially resolve local potentials at scales down to 2 nm, while maintaining atomic scale STM imaging, all at scan sizes of up to 15 microns. A mm-range two-dimensional coarse positioning stage and the ability to operate from liquid helium to room temperature with a fast turn-around time greatly expand the versatility of the instrument. Use of carefully selected model materials, combined with excellent topographic and voltage resolution has allowed us to distinguish measurement artifacts caused by surface roughness from true potentiometric features, a major problem in previous STP measurements. The measurements demonstrate that STP can produce physically meaningful results for homogeneous transport as well as non-uniform conduction dominated by material microstructures. Measurements of several physically interesting materials systems are presented as well, revealing new behaviors at the smallest length sales. The results establish scanning tunneling potentiometry as a useful tool for physics and

  3. Correlation of Chromosomal Instability, Telomere Length and Telomere Maintenance in Microsatellite Stable Rectal Cancer: A Molecular Subclass of Rectal Cancer

    PubMed Central

    Boardman, Lisa A.; Johnson, Ruth A.; Viker, Kimberly B.; Hafner, Kari A.; Jenkins, Robert B.; Riegert-Johnson, Douglas L.; Smyrk, Thomas C.; Litzelman, Kristin; Seo, Songwon; Gangnon, Ronald E.; Engelman, Corinne D.; Rider, David N.; Vanderboom, Russell J.; Thibodeau, Stephen N.; Petersen, Gloria M.; Skinner, Halcyon G.

    2013-01-01

    Introduction Colorectal cancer (CRC) tumor DNA is characterized by chromosomal damage termed chromosomal instability (CIN) and excessively shortened telomeres. Up to 80% of CRC is microsatellite stable (MSS) and is historically considered to be chromosomally unstable (CIN+). However, tumor phenotyping depicts some MSS CRC with little or no genetic changes, thus being chromosomally stable (CIN-). MSS CIN- tumors have not been assessed for telomere attrition. Experimental Design MSS rectal cancers from patients ≤50 years old with Stage II (B2 or higher) or Stage III disease were assessed for CIN, telomere length and telomere maintenance mechanism (telomerase activation [TA]; alternative lengthening of telomeres [ALT]). Relative telomere length was measured by qPCR in somatic epithelial and cancer DNA. TA was measured with the TRAPeze assay, and tumors were evaluated for the presence of C-circles indicative of ALT. p53 mutation status was assessed in all available samples. DNA copy number changes were evaluated with Spectral Genomics aCGH. Results Tumors were classified as chromosomally stable (CIN-) and chromosomally instable (CIN+) by degree of DNA copy number changes. CIN- tumors (35%; n=6) had fewer copy number changes (<17% of their clones with DNA copy number changes) than CIN+ tumors (65%; n=13) which had high levels of copy number changes in 20% to 49% of clones. Telomere lengths were longer in CIN- compared to CIN+ tumors (p=0.0066) and in those in which telomerase was not activated (p=0.004). Tumors exhibiting activation of telomerase had shorter tumor telomeres (p=0.0040); and tended to be CIN+ (p=0.0949). Conclusions MSS rectal cancer appears to represent a heterogeneous group of tumors that may be categorized both on the basis of CIN status and telomere maintenance mechanism. MSS CIN- rectal cancers appear to have longer telomeres than those of MSS CIN+ rectal cancers and to utilize ALT rather than activation of telomerase. PMID:24278232

  4. Measurement of Two-Plasmon-Decay Dependence on Plasma Density Scale Length

    NASA Astrophysics Data System (ADS)

    Haberberger, D.

    2013-10-01

    An accurate understanding of the plasma scale-length (Lq) conditions near quarter-critical density is important in quantifying the hot electrons generated by the two-plasmon-decay (TPD) instability in long-scale-length plasmas. A novel target platform was developed to vary the density scale length and an innovative diagnostic was implemented to measure the density profiles above 1021 cm-3 where TPD is expected to have the largest growth. A series of experiments was performed using the four UV (351-nm) beams on OMEGA EP that varied the Lq by changing the radius of curvature of the target while maintaining a constant Iq/Tq. The fraction of laser energy converted to hot electrons (fhot) was observed to increase rapidly from 0.005% to 1% by increasing the plasma scale length from 130 μm to 300 μm, corresponding to target diameters of 0.4 mm to 8 mm. A new diagnostic was developed based on refractometry using angular spectral filters to overcome the large phase accumulation in standard interferometric techniques. The angular filter refractometer measures the refraction angles of a 10-ps, 263-nm probe laser after propagating through the plasma. An angular spectral filter is used in the Fourier plane of the probe beam, where the refractive angles of the rays are mapped to space. The edges of the filter are present in the image plane and represent contours of constant refraction angle. These contours are used to infer the phase of the probe beam, which are used to calculate the plasma density profile. In long-scale-length plasmas, the diagnostic currently measures plasma densities from ~1019 cm-3 to ~2 × 1021 cm-3. This material is based upon work supported by the Department of Energy National Nuclear Security Administration under Award Number DE-NA0001944. In collaboration with D. H. Edgell, S. X. Hu, S. Ivancic, R. Boni, C. Dorrer, and D. H. Froula (Laboratory for Laser Energetics, U. of Rochester).

  5. The fundamental operating principles of electronic root canal length measurement devices.

    PubMed

    Nekoofar, M H; Ghandi, M M; Hayes, S J; Dummer, P M H

    2006-08-01

    It is generally accepted that root canal treatment procedures should be confined within the root canal system. To achieve this objective the canal terminus must be detected accurately during canal preparation and precise control of working length during the process must be maintained. Several techniques have been used for determining the apical canal terminus including electronic methods. However, the fundamental electronic operating principles and classification of the electronic devices used in this method are often unknown and a matter of controversy. The basic assumption with all electronic length measuring devices is that human tissues have certain characteristics that can be modelled by a combination of electrical components. Therefore, by measuring the electrical properties of the model, such as resistance and impedance, it should be possible to detect the canal terminus. The root canal system is surrounded by dentine and cementum that are insulators to electrical current. At the minor apical foramen, however, there is a small hole in which conductive materials within the canal space (tissue, fluid) are electrically connected to the periodontal ligament that is itself a conductor of electric current. Thus, dentine, along with tissue and fluid inside the canal, forms a resistor, the value of which depends on their dimensions, and their inherent resistivity. When an endodontic file penetrates inside the canal and approaches the minor apical foramen, the resistance between the endodontic file and the foramen decreases, because the effective length of the resistive material (dentine, tissue, fluid) decreases. As well as resistive properties, the structure of the tooth root has capacitive characteristics. Therefore, various electronic methods have been developed that use a variety of other principles to detect the canal terminus. Whilst the simplest devices measure resistance, other devices measure impedance using either high frequency, two frequencies, or

  6. Single Molecule Bioelectronics and Their Application to Amplification-Free Measurement of DNA Lengths.

    PubMed

    Gül, O Tolga; Pugliese, Kaitlin M; Choi, Yongki; Sims, Patrick C; Pan, Deng; Rajapakse, Arith J; Weiss, Gregory A; Collins, Philip G

    2016-01-01

    As biosensing devices shrink smaller and smaller, they approach a scale in which single molecule electronic sensing becomes possible. Here, we review the operation of single-enzyme transistors made using single-walled carbon nanotubes. These novel hybrid devices transduce the motions and catalytic activity of a single protein into an electronic signal for real-time monitoring of the protein's activity. Analysis of these electronic signals reveals new insights into enzyme function and proves the electronic technique to be complementary to other single-molecule methods based on fluorescence. As one example of the nanocircuit technique, we have studied the Klenow Fragment (KF) of DNA polymerase I as it catalytically processes single-stranded DNA templates. The fidelity of DNA polymerases makes them a key component in many DNA sequencing techniques, and here we demonstrate that KF nanocircuits readily resolve DNA polymerization with single-base sensitivity. Consequently, template lengths can be directly counted from electronic recordings of KF's base-by-base activity. After measuring as few as 20 copies, the template length can be determined with <1 base pair resolution, and different template lengths can be identified and enumerated in solutions containing template mixtures. PMID:27348011

  7. Identification of source of oscillations in apparent sarcomere length measured by laser diffraction.

    PubMed Central

    Burton, K; Huxley, A F

    1995-01-01

    The most widely used technique for dynamic estimates of sarcomere length in muscle is laser light diffraction. We have identified conditions under which artifactual oscillations can arise in apparent sarcomere length measured by this technique and report methods to reduce the effect. Altringham et al. (1984) first reported that the diffraction angle can exhibit one cycle of oscillation for each sarcomere length displacement of the illuminated portion of the fiber. We find that the amplitude of similar oscillations is strongly dependent on the intensity of light scattered from objects near the fiber and on the spacing between fiber and scatterer. The oscillations can be eliminated by minimizing scattered light and positioning the fiber a few millimeters from sources of scattering. A theoretical description shows that oscillations of this kind are expected from interference of scattered and diffracted light. Interference fringes were observed along the meridian of the pattern, and these moved during translation of either a fiber or a grating. The movement of fringes across the diffraction order shifts the centroid back and forth and, when associated with steady shortening, can give rise to "steps" and "pauses" in apparent striation spacing. Images FIGURE 1 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 PMID:7647247

  8. Microlenses focal length measurement using Z-scan and parallel moiré deflectometry

    NASA Astrophysics Data System (ADS)

    Rasouli, Saifollah; Rajabi, Y.; Sarabi, H.

    2013-12-01

    In this paper, a simple and accurate method based on Z-scan and parallel moiré deflectometry for measuring the focal length of microlenses is reported. A laser beam is focused by one lens and is re-collimated by another lens, and then strikes a parallel moiré deflectometer. In the presence of a microlens near the focal point of the first lens, the radius of curvature of the beam is changed; the parallel moiré fringes are formed only due to the beam divergence or convergence. The focal length of the microlens is obtained from the moiré fringe period graph without the need to know the position of the principal planes. This method is simple, more reliable, and completely automated. The implementation of the method is straightforward. Since a focused laser beam and Z-scan in free space are used, it can be employed for determining small focal lengths of small size microlenses without serious limitation on their size.

  9. Measurement and Correlation of Ice Accretion Roughness

    NASA Technical Reports Server (NTRS)

    Anderson, David N.; Hentschel, Daniel B.; Ruff, Gary A.

    2003-01-01

    Measurements were taken of the roughness characteristics of ice accreted on NACA 0012 airfoils in the NASA Glenn Icing Research Tunnel (IRT). Tests were conducted with size scaled, using models with chords of 26.7, 53.3, and 80.0 cm, and with liquid-water content scaled, both according to previously-tested scaling methods. The width of the smooth zone which forms on either side of the leading edge of the airfoil and the diameter of the roughness elements are presented in non-dimensional form as functions of the accumulation parameter. The smooth-zone width was found to decrease with increasing accumulation parameter. The roughness-element diameter increased with accumulation parameter until a plateau was reached. This maximum diameter was about 0.06 times twice the model leading-edge radius. Neither smooth-zone width nor element diameter were affected by a change in freezing fraction from 0.2 to 0.4. Both roughness characteristics appeared to scale with model size and with liquid-water content.

  10. Acoustic method for measuring the sound speed of gases over small path lengths.

    PubMed

    Olfert, J S; Checkel, M D; Koch, C R

    2007-05-01

    Acoustic "phase shift" methods have been used in the past to accurately measure the sound speed of gases. In this work, a phase shift method for measuring the sound speed of gases over small path lengths is presented. We have called this method the discrete acoustic wave and phase detection (DAWPD) method. Experimental results show that the DAWPD method gives accurate (+/-3.2 ms) and predictable measurements that closely match theory. The sources of uncertainty in the DAWPD method are examined and it is found that ultrasonic reflections and changes in the frequency ratio of the transducers (the ratio of driving frequency to resonant frequency) can be major sources of error. Experimentally, it is shown how these sources of uncertainty can be minimized. PMID:17552851

  11. Measurements of the effect of free-stream turbulence length scale on heat transfer

    NASA Astrophysics Data System (ADS)

    Moss, R. W.; Oldfield, M. L. G.

    1992-06-01

    The effects of free-stream turbulence scale on heat transfer through a turbulent flat plate boundary layer have been measured. A variety of turbulence spectra were produced by parallel bar grids. The design of these was guided by previous measurements of combustion chamber turbulence. Heat transfer was measured transiently using thin film gauges. The heat transfer to the plate was found to be a function of turbulence integral length scale as well as intensity, and is of relevance to gas turbine heat transfer where airfoils are subject to high turbulence levels from the combustor. Enhancement factors of up to 40 percent were experienced and the results extend conclusions drawn by other workers to higher turbulence levels and scales.

  12. Inlet Turbulence and Length Scale Measurements in a Large Scale Transonic Turbine Cascade

    NASA Technical Reports Server (NTRS)

    Thurman, Douglas; Flegel, Ashlie; Giel, Paul

    2014-01-01

    Constant temperature hotwire anemometry data were acquired to determine the inlet turbulence conditions of a transonic turbine blade linear cascade. Flow conditions and angles were investigated that corresponded to the take-off and cruise conditions of the Variable Speed Power Turbine (VSPT) project and to an Energy Efficient Engine (EEE) scaled rotor blade tip section. Mean and turbulent flowfield measurements including intensity, length scale, turbulence decay, and power spectra were determined for high and low turbulence intensity flows at various Reynolds numbers and spanwise locations. The experimental data will be useful for establishing the inlet boundary conditions needed to validate turbulence models in CFD codes.

  13. Direct Measurement of Sub-Debye-Length Attraction between Oppositely Charged Surfaces

    NASA Astrophysics Data System (ADS)

    Kampf, Nir; Ben-Yaakov, Dan; Andelman, David; Safran, S. A.; Klein, Jacob

    2009-09-01

    Using a surface force balance with fast video analysis, we have measured directly the attractive forces between oppositely charged solid surfaces (charge densities σ+, σ-) across water over the entire range of interaction, in particular, at surface separations D below the Debye screening length λS. At very low salt concentration we find a long-ranged attraction between the surfaces (onset ca. 100 nm), whose variation at D<λS agrees well with predictions based on solving the Poisson-Boltzmann theory, when due account is taken of the independently-determined surface charge asymmetry (σ+≠|σ-|).

  14. Diffusion length measurement using the scanning electron microscope. [for silicon solar cell

    NASA Technical Reports Server (NTRS)

    Weizer, V. G.

    1975-01-01

    The present work describes a measuring technique employing the scanning electron microscope in which values of the true bulk diffusion length are obtained. It is shown that surface recombination effects can be eliminated through application of highly doped surface field layers. The effects of high injection level and low-high junction current generation are investigated. Results obtained with this technique are compared to those obtained by a penetrating radiation (X-ray) method, and a close agreement is found. The SEM technique is limited to cells that contain a back surface field layer.

  15. Method for high-accuracy multiplicity-correlation measurements

    NASA Astrophysics Data System (ADS)

    Gulbrandsen, K.; Søgaard, C.

    2016-04-01

    Multiplicity-correlation measurements provide insight into the dynamics of high-energy collisions. Models describing these collisions need these correlation measurements to tune the strengths of the underlying QCD processes which influence all observables. Detectors, however, often possess limited coverage or reduced efficiency that influence correlation measurements in obscure ways. In this paper, the effects of nonuniform detection acceptance and efficiency on the measurement of multiplicity correlations between two distinct detector regions (termed forward-backward correlations) are derived. An analysis method with such effects built in is developed and subsequently verified using different event generators. The resulting method accounts for acceptance and efficiency in a model-independent manner with high accuracy, thereby shedding light on the relative contributions of the underlying processes to particle production.

  16. Monotonic correlation analysis of image quality measures for image fusion

    NASA Astrophysics Data System (ADS)

    Kaplan, Lance M.; Burks, Stephen D.; Moore, Richard K.; Nguyen, Quang

    2008-04-01

    The next generation of night vision goggles will fuse image intensified and long wave infra-red to create a hybrid image that will enable soldiers to better interpret their surroundings during nighttime missions. Paramount to the development of such goggles is the exploitation of image quality (IQ) measures to automatically determine the best image fusion algorithm for a particular task. This work introduces a novel monotonic correlation coefficient to investigate how well possible IQ features correlate to actual human performance, which is measured by a perception study. The paper will demonstrate how monotonic correlation can identify worthy features that could be overlooked by traditional correlation values.

  17. High Frequency Click-Evoked Otoacoustic Emission Measurements Using Maximum Length Sequences

    NASA Astrophysics Data System (ADS)

    Lineton, B.; Sohal, R.; Harvey, E.; Thornton, A. R. D.

    2011-11-01

    The aim of the study was to compare high-frequency components (4-8 kHz) of click-evoked otoacoustic emissions (CEOAEs) recorded using two different stimulus paradigms: the double-evoked (DE) paradigm, which uses two earphones, and the rate-derived nonlinear (RDNL) paradigm, which uses maximum length sequences (MLS) in a single ear-phone. Recordings were made in 20 otologically normal ears, and the results compared in terms of the apparent stimulus artefacts, and the presence of high-frequency CEOAEs. The correlation between CEOAEs amplitudes and DPOAE amplitudes from 4-8 kHz were also calculated. The results showed that, for both paradigms, the stimulus artefacts were of similar amplitudes and had largely decayed by around 1.5-2 ms post stimulus. Though similar in amplitude, the morphology of the artefacts in the two paradigms showed some differences, suggesting a possible means of identification. The CEOAE waveforms (post 2 ms) were very similar in both paradigms, and contained significant energy from 4-8 kHz. The amplitude correlated with the mean DPOAE amplitude from 4-8 kHz (R = 0.7; p<0.001).

  18. Measurement of intact-core length of atomizing liquid jets by image deconvolution

    NASA Astrophysics Data System (ADS)

    Woodward, Roger; Burch, Robert; Kuo, Kenneth; Cheung, Fan-Bill

    1993-11-01

    The investigation of liquid jet breakup and spray development is critical to the understanding of combustion phenomena in liquid propellant rocket engines. Much work has been done to characterize low-speed liquid jet breakup and dilute sprays, but atomizing jets and dense sprays have yielded few quantitative measurements due to their high liquid load fractions and hence their optical opacity. Focus was on a characteristic of the primary breakup process of round liquid jets, namely the length of the intact-liquid core. The specific application considered is that of shear-coaxial-type rocket engine injectors in which liquid oxygen is injected through the center post while high velocity gaseous hydrogen is injected through a concentric annulus, providing a shear force to the liquid jet surface. Real-time x ray radiography, capable of imaging through the dense two-phase region surrounding the liquid core, is used to make the measurements. The intact-liquid-core length data were obtained and interpreted using two conceptually different methods to illustrate the effects of chamber pressure, gas-to-liquid momentum ratio, and cavitation.

  19. Simultaneous measurement of focal length and index of refraction of a microlens using a compound microscope

    NASA Astrophysics Data System (ADS)

    Chollet, Franck; Ashraf, Mohammed

    2009-10-01

    The fabrication of microlenses has spurred a lot of interest and resulted in multiple techniques of fabrication in the past decade. However the metrology of these lenses has received less attention and remains a complex and time-consuming task that does not allow frequent control during development and manufacturing. We propose a simple technique based on a standard compound microscope that would allow measuring the focal length of a plano-convex lens and at the same time obtain a measure of the index of refraction of the lens material. The method relies on observing the different images of an object placed in the illumination path of the microscope. Among these images, some are created by the light going through the lens and others by its reflection on the surface. We show that with the image distance and size it is possible to retrieve the focal length and the average index of refraction of the lens material in the case of quasi-spherical lenses. The accuracy obtained by the technique is better than a few per cent and its cost is negligible as it only uses existing equipment.

  20. Measurement of intact-core length of atomizing liquid jets by image deconvolution

    NASA Technical Reports Server (NTRS)

    Woodward, Roger; Burch, Robert; Kuo, Kenneth; Cheung, Fan-Bill

    1993-01-01

    The investigation of liquid jet breakup and spray development is critical to the understanding of combustion phenomena in liquid propellant rocket engines. Much work has been done to characterize low-speed liquid jet breakup and dilute sprays, but atomizing jets and dense sprays have yielded few quantitative measurements due to their high liquid load fractions and hence their optical opacity. Focus was on a characteristic of the primary breakup process of round liquid jets, namely the length of the intact-liquid core. The specific application considered is that of shear-coaxial-type rocket engine injectors in which liquid oxygen is injected through the center post while high velocity gaseous hydrogen is injected through a concentric annulus, providing a shear force to the liquid jet surface. Real-time x ray radiography, capable of imaging through the dense two-phase region surrounding the liquid core, is used to make the measurements. The intact-liquid-core length data were obtained and interpreted using two conceptually different methods to illustrate the effects of chamber pressure, gas-to-liquid momentum ratio, and cavitation.

  1. Modeling work zone crash frequency by quantifying measurement errors in work zone length.

    PubMed

    Yang, Hong; Ozbay, Kaan; Ozturk, Ozgur; Yildirimoglu, Mehmet

    2013-06-01

    Work zones are temporary traffic control zones that can potentially cause safety problems. Maintaining safety, while implementing necessary changes on roadways, is an important challenge traffic engineers and researchers have to confront. In this study, the risk factors in work zone safety evaluation were identified through the estimation of a crash frequency (CF) model. Measurement errors in explanatory variables of a CF model can lead to unreliable estimates of certain parameters. Among these, work zone length raises a major concern in this analysis because it may change as the construction schedule progresses generally without being properly documented. This paper proposes an improved modeling and estimation approach that involves the use of a measurement error (ME) model integrated with the traditional negative binomial (NB) model. The proposed approach was compared with the traditional NB approach. Both models were estimated using a large dataset that consists of 60 work zones in New Jersey. Results showed that the proposed improved approach outperformed the traditional approach in terms of goodness-of-fit statistics. Moreover it is shown that the use of the traditional NB approach in this context can lead to the overestimation of the effect of work zone length on the crash occurrence. PMID:23563145

  2. Do severity measures explain differences in length of hospital stay? The case of hip fracture.

    PubMed Central

    Shwartz, M; Iezzoni, L I; Ash, A S; Mackiernan, Y D

    1996-01-01

    OBJECTIVE: To examine whether judgments about hospital length of stay (LOS) vary depending on the measure used to adjust for severity differences. DATA SOURCES/STUDY SETTING: Data on admissions to 80 hospitals nationwide in the 1992 MedisGroups Comparative Database. STUDY DESIGN: For each of 14 severity measures, LOS was regressed on patient age/sex, DRG, and severity score. Regressions were performed on trimmed and untrimmed data. R-squared was used to evaluate model performance. For each severity measure for each hospital, we calculated the expected LOS and the z-score, a measure of the deviation of observed from expected LOS. We ranked hospitals by z-scores. DATA EXTRACTION: All patients admitted for initial surgical repair of a hip fracture, defined by DRG, diagnosis, and procedure codes. PRINCIPAL FINDINGS: The 5,664 patients had a mean (s.d.) LOS of 11.9 (8.9) days. Cross-validated R-squared values from the multivariable regressions (trimmed data) ranged from 0.041 (Comorbidity Index) to 0.165 (APR-DRGs). Using untrimmed data, observed average LOS for hospitals ranged from 7.6 to 23.9 days. The 14 severity measures showed excellent agreement in ranking hospitals based on z-scores. No severity measure explained the differences between hospitals with the shortest and longest LOS. CONCLUSIONS: Hospitals differed widely in their mean LOS for hip fracture patients, and severity adjustment did little to explain these differences. PMID:8885854

  3. Measuring Scale Errors in a Laser Tracker's Horizontal Angle Encoder Through Simple Length Measurement and Two-Face System Tests.

    PubMed

    Muralikrishnan, B; Blackburn, C; Sawyer, D; Phillips, S; Bridges, R

    2010-01-01

    We describe a method to estimate the scale errors in the horizontal angle encoder of a laser tracker in this paper. The method does not require expensive instrumentation such as a rotary stage or even a calibrated artifact. An uncalibrated but stable length is realized between two targets mounted on stands that are at tracker height. The tracker measures the distance between these two targets from different azimuthal positions (say, in intervals of 20° over 360°). Each target is measured in both front face and back face. Low order harmonic scale errors can be estimated from this data and may then be used to correct the encoder's error map to improve the tracker's angle measurement accuracy. We have demonstrated this for the second order harmonic in this paper. It is important to compensate for even order harmonics as their influence cannot be removed by averaging front face and back face measurements whereas odd orders can be removed by averaging. We tested six trackers from three different manufacturers. Two of those trackers are newer models introduced at the time of writing of this paper. For older trackers from two manufacturers, the length errors in a 7.75 m horizontal length placed 7 m away from a tracker were of the order of ± 65 μm before correcting the error map. They reduced to less than ± 25 μm after correcting the error map for second order scale errors. Newer trackers from the same manufacturers did not show this error. An older tracker from a third manufacturer also did not show this error. PMID:27134789

  4. Precision measurement of {pi}{pi} scattering lengths at the NA48/2 experiment

    SciTech Connect

    Venditti, Stefano

    2010-12-28

    The NA48/2 experiment at CERN [1] collected {approx}18{center_dot}10{sup 9} charged kaon decays during the years 2003/4. Along with the primary goals of the collaboration, i.e. the measurement of the CP-violating asymmetry in the K{sup {+-}}{yields}{pi}{sup {+-}}{pi}{sup +}{pi}{sup -} and K{sup {+-}}{yields}{pi}{sup {+-}}{pi}{sup 0}{pi}{sup 0} decays thanks to the simultaneous collection of K{sup +} and K{sup -} events, the collected data allowed to perform many other interesting analyses. In this paper two independent measurements of {pi}{pi} scattering lengths will be reviewed, using NA48/2 data from the K{sup {+-}}{yields}e{sup {+-}}{nu}{pi}{sup +}{pi}{sup -} decay and from the cusp effect in K{sup {+-}}{yields}{pi}{sup {+-}}{pi}{sup +}{pi}{sup -} respectively.

  5. Diffusion length measurements in bulk and epitaxially grown 3-5 semiconductors using charge collection microscopy

    NASA Technical Reports Server (NTRS)

    Leon, R. P.

    1987-01-01

    Diffusion lengths and surface recombination velocities were measured in GaAs diodes and InP finished solar cells. The basic techniques used was charge collection microscopy also known as electron beam induced current (EBIC). The normalized currents and distances from the pn junction were read directly from the calibrated curves obtained while using the line scan mode in an SEM. These values were then equated to integral and infinite series expressions resulting from the solution of the diffusion equation with both extended generation and point generation functions. This expands previous work by examining both thin and thick samples. The surface recombination velocity was either treated as an unknown in a system of two equations, or measured directly using low e(-) beam accelerating voltages. These techniques give accurate results by accounting for the effects of surface recombination and the finite size of the generation volume.

  6. Multifunctional optical correlator for picosecond ultraviolet laser pulse measurement

    DOE PAGESBeta

    Rakhman, Abdurahim; Wang, Yang; Garcia, Frances; Long, Cary D.; Huang, Chunning; Takeda, Yasuhiro; Liu, Yun

    2014-01-01

    A compact optical correlator system that measures both the autocorrelation between two infrared (IR) lights and the cross-correlation between an IR and an ultraviolet (UV) light using a single nonlinear optical crystal has been designed and experimentally demonstrated. The rapid scanning of optical delay line, switching between auto and cross-correlations, crystal angle tuning, and data acquisition and processing are all computer controlled. Pulse widths of an IR light from a mode-locked laser are measured by the correlator and the results are compared with a direct measurement using a high-speed photodetector system. The correlator has been used to study the parametermore » dependence of the pulse width of a macropulse UV laser designed for laser-assisted hydrogen ion (H-) beam stripping for the Spallation Neutron Source at Oak Ridge National Laboratory.« less

  7. Multifunctional optical correlator for picosecond ultraviolet laser pulse measurement

    SciTech Connect

    Rakhman, Abdurahim; Wang, Yang; Garcia, Frances; Long, Cary D.; Huang, Chunning; Takeda, Yasuhiro; Liu, Yun

    2014-01-01

    A compact optical correlator system that measures both the autocorrelation between two infrared (IR) lights and the cross-correlation between an IR and an ultraviolet (UV) light using a single nonlinear optical crystal has been designed and experimentally demonstrated. The rapid scanning of optical delay line, switching between auto and cross-correlations, crystal angle tuning, and data acquisition and processing are all computer controlled. Pulse widths of an IR light from a mode-locked laser are measured by the correlator and the results are compared with a direct measurement using a high-speed photodetector system. The correlator has been used to study the parameter dependence of the pulse width of a macropulse UV laser designed for laser-assisted hydrogen ion (H-) beam stripping for the Spallation Neutron Source at Oak Ridge National Laboratory.

  8. Spin–spin correlation length in a two-dimensional frustrated magnet and its relation to doping

    SciTech Connect

    Mikheyenkov, A. V.; Valiullin, V. E.; Shvartsberg, A. V.; Barabanov, A. F.

    2015-09-15

    In a spherically symmetric self-consistent approach (SSSA), the spin-1/2 J{sub 1}–J{sub 2} Heisenberg model on a two-dimensional square lattice is considered for two-time retarded spin–spin Green’s functions. The spin excitation spectrum, ω(q), and spin gaps at symmetric points are obtained for the entire J{sub 1}–J{sub 2} diagram, i.e., for any ϕ, J{sub 1} = cosϕ, and J{sub 2} = sinϕ. The structure factor c{sub q} and the correlation length ξ at finite temperature are calculated in the entire range of parameters. A radical difference in the behavior of the system in the upper, frustrated (0 ⩽ ϕ ⩽ π), and the lower, nonfrustrated (π ⩽ ϕ ⩽ 2π), regions of the diagram is demonstrated. In the latter region, there is a first-order phase transition that is unique on the phase diagram. For a weakly frustrated antiferromagnet (J{sub 1} > J{sub 2} > 0), the results obtained are compared with the experimental dependence of ξ on temperature and doping level. A correspondence rule is proposed between frustration in a spin model and the doping of an antiferromagnet with holes.

  9. Visual Decisions in the Presence of Measurement and Stimulus Correlations

    PubMed Central

    Bhardwaj, Manisha; Carroll, Samuel; Ma, Wei Ji; Josić, Krešimir

    2015-01-01

    Humans and other animals base their decisions on noisy sensory input. Much work has been devoted to understanding the computations that underlie such decisions. The problem has been studied in a variety of tasks and with stimuli of differing complexity. However, how the statistical structure of stimuli, along with perceptual measurement noise, affects perceptual judgments is not well understood. Here we examine how correlations between the components of a stimulus—stimulus correlations—together with correlations in sensory noise, affect decision making. As an example, we consider the task of detecting the presence of a single or multiple targets among distractors. We assume that both the distractors and the observer’s measurements of the stimuli are correlated. The computations of an optimal observer in this task are nontrivial yet can be analyzed and understood intuitively. We find that when distractors are strongly correlated, measurement correlations can have a strong impact on performance. When distractor correlations are weak, measurement correlations have little impact unless the number of stimuli is large. Correlations in neural responses to structured stimuli can therefore have a strong impact on perceptual judgments. PMID:26378875

  10. Enhancing robustness of multiparty quantum correlations using weak measurement

    SciTech Connect

    Singh, Uttam; Mishra, Utkarsh; Dhar, Himadri Shekhar

    2014-11-15

    Multipartite quantum correlations are important resources for the development of quantum information and computation protocols. However, the resourcefulness of multipartite quantum correlations in practical settings is limited by its fragility under decoherence due to environmental interactions. Though there exist protocols to protect bipartite entanglement under decoherence, the implementation of such protocols for multipartite quantum correlations has not been sufficiently explored. Here, we study the effect of local amplitude damping channel on the generalized Greenberger–Horne–Zeilinger state, and use a protocol of optimal reversal quantum weak measurement to protect the multipartite quantum correlations. We observe that the weak measurement reversal protocol enhances the robustness of multipartite quantum correlations. Further it increases the critical damping value that corresponds to entanglement sudden death. To emphasize the efficacy of the technique in protection of multipartite quantum correlation, we investigate two proximately related quantum communication tasks, namely, quantum teleportation in a one sender, many receivers setting and multiparty quantum information splitting, through a local amplitude damping channel. We observe an increase in the average fidelity of both the quantum communication tasks under the weak measurement reversal protocol. The method may prove beneficial, for combating external interactions, in other quantum information tasks using multipartite resources. - Highlights: • Extension of weak measurement reversal scheme to protect multiparty quantum correlations. • Protection of multiparty quantum correlation under local amplitude damping noise. • Enhanced fidelity of quantum teleportation in one sender and many receivers setting. • Enhanced fidelity of quantum information splitting protocol.

  11. Estimators for Two Measures of Association for Set Correlation.

    ERIC Educational Resources Information Center

    Cohen, Jacob; Nee, John C. M.

    1984-01-01

    Two measures of association between sets of variables have been proposed for set correlation: the proportion of generalized variance, and the proportion of additionive variance. Because these measures are strongly positively biased, approximate expected values and estimators of these measures are derived and checked. (Author/BW)

  12. Intra- and inter-observer reliability of combined segmental measurement techniques for predicting immediate post-deployment intraluminal tracheal stent length in dogs.

    PubMed

    Monaco, Thomas A; Taylor, Jim A; Langenbach, Anke; Gordon, Sebastian; Vance, Eric

    2014-05-01

    This study evaluated segmental measurement techniques for predicting immediate post-deployment intraluminal tracheal stent length in dogs with naturally occurring tracheal collapse. Radiographs of 12 client-owned dogs that underwent intraluminal tracheal stent placement were retrospectively reviewed. Tracheal lengths were divided into 1, 2, 3, or 4 equal segments. Stent lengths were predicted using the widest dorsoventral height of each segment, with and without the addition of 10%, and an accompanying foreshortening chart. Techniques were compared for intra- and inter-observer reliability, and post-deployment stent length predictability. There was good to high intra- and inter-observer reliability for all segmental measurements; median intra-class correlation coefficients were 0.98 and 0.92, respectively. Measuring 2 segments without the addition of 10% to the widths was significantly more accurate in predicting immediate post-deployment stent length in terms of percent (P = 0.03) and absolute difference (P = 0.02). Segmental measuring techniques are repeatable amongst observers and may help guide stent selection. PMID:24790228

  13. Effect of a magnetic field on crack length measurement of 9NI steel by unloading compliance method

    NASA Astrophysics Data System (ADS)

    Nagasaki, C.; Matsui, K.; Shibata, K.

    2002-05-01

    In the fracture toughness measurement of ferro-magnetic materials in high magnetic fields, it has not been clarified whether we can use the same formulas as ones used in a non-magnetic field. Therefore, it is necessary to understand the magnetic effect in the fracture toughness measurement of ferro-magnetic materials. As the first step, crack length was measured at 4 K by unloading compliance method in the testing of CT specimen of 9% nickel steel. The same formula was used in the magnetic field of 0 and 8 Tesla. They were compared with the length measured by optical fractography. The magnetic field had little effect on the crack length measurement by the unloading compliance method. The small amount of retained austenite in Q T heat-treated specimen did not exhibit a magnetic effect on the crack length measurement by the unloading compliance method.

  14. Correlation of anterior segment optical coherence tomography measurements with graft trephine diameter following descemet stripping automated endothelial keratoplasty

    PubMed Central

    2012-01-01

    Background To assess repeatability of the Zhongshan Assessment Program (ZAP) software measurement of Anterior Segment Optical Coherence Tomography (ASOCT) images and correlate with graft trephine diameter following Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) Methods Retrospectively evaluated interventional case series. 121 consecutive eyes undergoing DSAEK over a 26 month period underwent ASOCT imaging 1month after their surgery. ASOCT images were processed using ZAP software which measured the graft and cornea parameters including anterior and posterior graft arc length and cord length, posterior cornea arc length (PCAL) and anterior chamber width. Results The graft measurements showed good repeatability on ASOCT using ZAP with high intra class coefficient and small variation in the coefficient of variation. On ASOCT, the mean recipient PCAL was 12.99+/−0.69mm and the anterior chamber width was 11.16+/−0.57mm. The mean Graft anterior arc length was 9.69+/−0.66mm and the mean Graft anterior cord length was 8.92+/−2.94mm. The mean graft posterior arc length was 9.24+/−0.75mm and the mean graft posterior cord length was 8.15+/−0.57mm. Graft posterior arc length (rho=0.788, p< 0.001) correlated best with intra-operative graft trephine diameter. The mean ratio of posterior graft arc length to PCAL was 0.712 +/− 0.056. Conclusions We have validated the repeatability of the ZAP software for DSAEK graft measurements from ASOCT images and shown that the graft arc length parameters calculated from the ASOCT images correlate well with the intra-operative graft trephine diameter. This software may help surgeons determine the optimal DSAEK graft size based on pre-operative ASOCT measurements of the recipient eye. PMID:22824516

  15. Diffraction effects in coherent transition radiation diagnostics for sub-mm bunch length measurement

    SciTech Connect

    Maxwell, T.J.; Mihalcea, D.; Piot, P.; /Northern Illinois U. /Fermilab

    2008-09-01

    Electrons crossing the boundary between different media generate bursts of transition radiation. In the case of bunches of N electrons, the radiation is coherent and has an N-squared enhancement at wavelengths related to the longitudinal bunch distribution. This coherent transition radiation has therefore attracted attention as an interceptive charged particle beam diagnostic technique. Many analytical descriptions have been devised describing the spectral distribution generated by electron bunches colliding with thin metallic foils making different simplifying assumptions. For typical bunches having lengths in the sub-millimeter range, measurable spectra are generated up into the millimeter range. Analysis of this THz radiation is performed using optical equipment tens of millimeters in size. This gives rise to concern that optical diffraction effects may spread the wavefront of interest into regions larger than the optical elements and partially escape detection, generating a wavelength-dependent instrument response. In this paper we present a model implementing vector diffraction theory to analyze these effects in bunch length diagnostics based on coherent transition radiation.

  16. Turbulent transport and length scale measurement experiments with comfined coaxial jets

    NASA Technical Reports Server (NTRS)

    Johnson, B. V.; Roback, R.

    1984-01-01

    A three phase experimental study of mixing downstream of swirling and nonswirling confined coaxial jets was conducted to obtain data for the evaluation and improvement of turbulent transport models currently employed in a variety of computational procedures. The present effort was directed toward the acquisition of length scale and dissipation rate data that provide more accurate inlet boundary conditions for the computational procedures and a data base to evaluate the turbulent transport models in the near jet region where recirculation does not occur, and the acquisition of mass and momentum turbulent transport data for a nonswirling flow condition with a blunt inner jet inlet configuration rather than the tapered inner jet inlet. A measurement technique, generally used to obtain approximate integral length and microscales of turbulence and dissipation rates, was computerized. Results showed the dissipation rate varied by 2 1/2 orders of magnitude across the inlet plane, by 2 orders of magnitude 51 mm from the inlet plane, and by 1 order of magnitude at 102 mm from the inlet plane for a nonswirling flow test conditions.

  17. Axial Length Measurement Failure Rates with the IOLMaster and Lenstar LS 900 in Eyes with Cataract

    PubMed Central

    Pesudovs, Konrad; Yang, Xin; Bao, Fangjun; Yu, Ayong; Lin, Shishi; Feng, Yifan; Huang, Jinhai

    2015-01-01

    Purpose To evaluate axial length (AL) measurement failure rate with the IOLMaster (Carl Zeiss AG, Germany) and Lenstar LS 900 (Haag-Streit AG, Switzerland) in eyes with cataract. Methods Two hundred and ninety-six eyes of 170 patients with cataract were enrolled. Cataract type and severity were graded using the Lens Opacities Classification System III (LOCS III) and AL measurements were attempted with IOLMaster (version 5.4) and Lenstar LS 900 (version 1.1). Chi-squared analysis was used to assess if the difference in AL measurement acquisition rate was statistically significant between the two devices. The association of the different cataract types and severity with the AL measurement acquisition rate was evaluated with logistic regression analysis. Results AL measurements were obtained in 184 eyes (62.16%) using the IOLMaster and 191 eyes (64.53%) using the Lenstar, which corresponds to a failure rate of 37.84% and 35.47% respectively. Chi-square analysis indicated no significant difference between the Lenstar and IOLMaster for AL measurement failure rate (x2 = 0.356, P = 0.550). Logistic regression analysis indicated no association between acquisition rates and cortical or nuclear cataracts with either device. There was a statistically significant association between acquisition rates and increasing severity of posterior subcapsular cataracts with the IOLMaster (β = -1.491, P<0.001) and Lenstar LS 900 (β = -1.507, P<0.001). Conclusion The IOLMaster and Lenstar LS 900 have similar AL measurement failure rates (35–38%) for Chinese public hospital cataract patients. Increasing severity of posterior subcapsular cataracts was problematic for both devices. PMID:26061554

  18. Flow rate and slip length measurements of water in single micrometer pipes

    NASA Astrophysics Data System (ADS)

    Taborek, Peter; Kannan, Anerudh; Mallin, David; Velasco, Angel

    2014-11-01

    Measurements of pressure driven water flows in hydrophobic and hydrophilic fused quartz capillaries of 1.8 um diameter are compared. Typical flow rates of 1 picoliter/s and pressure drops up to 25 Atm were used. Water exited the capillaries into an oil reservoir where the volume of the pendant drop could be monitored using time lapse photography. The typical growth rate for the drop diameter was ~300 μm per day. The drop size saturates due to diffusion at the interface. For the untreated quartz capillary the results are consistent with a slip of zero. The hydrophilic capillaries are chemically treated with octadecyltrichlorosilane (OTS) to form hydrophobic surfaces. Successful surface preparation is confirmed with the absence of capillary rise. Our technique can detect slip lengths above 20 nm.

  19. Computable measure of total quantum correlations of multipartite systems

    NASA Astrophysics Data System (ADS)

    Behdani, Javad; Akhtarshenas, Seyed Javad; Sarbishaei, Mohsen

    2016-04-01

    Quantum discord as a measure of the quantum correlations cannot be easily computed for most of density operators. In this paper, we present a measure of the total quantum correlations that is operationally simple and can be computed effectively for an arbitrary mixed state of a multipartite system. The measure is based on the coherence vector of the party whose quantumness is investigated as well as the correlation matrix of this part with the remainder of the system. Being able to detect the quantumness of multipartite systems, such as detecting the quantum critical points in spin chains, alongside with the computability characteristic of the measure, makes it a useful indicator to be exploited in the cases which are out of the scope of the other known measures.

  20. The formation of interstellar molecular lines in a turbulent velocity field with finite correlation length III. Spherical clouds in hydrostatic equilibrium.

    NASA Astrophysics Data System (ADS)

    Piehler, G.; Kegel, W. H.

    1995-05-01

    We investigated the formation of interstellar molecular lines in a turbulent velocity field with finite correlation length, extending previous work (Albrecht & Kegel 1987; Kegel et al. 1992) to isothermal spheres in hydrostatic equilibrium as cloud models with σ>>v_ therm _. For this we use the transformed generalized radiative transfer equation (Kegel et al. 1992). We concentrate our calculations on the CO-molecule with up to 12 energy levels. We give numerical results for models with T_kin_=50K, σ=3.9km/sec (σ/v_ therm _=22), and different values of the central H_2_ density and different values of the correlation length. As our results show, accounting for a velocity field with a finite correlation length affects the line profiles, the center-to-limb variation, and the intensity ratios. We find that the higher transitions are more strongly affected than the J=1-0 transition.

  1. Measurement of the neutron-neutron scattering length using the π-d capture reaction

    NASA Astrophysics Data System (ADS)

    Chen, Q.; Howell, C. R.; Carman, T. S.; Gibbs, W. R.; Gibson, B. F.; Hussein, A.; Kiser, M. R.; Mertens, G.; Moore, C. F.; Morris, C.; Obst, A.; Pasyuk, E.; Roper, C. D.; Salinas, F.; Setze, H. R.; Slaus, I.; Sterbenz, S.; Tornow, W.; Walter, R. L.; Whiteley, C. R.; Whitton, M.

    2008-05-01

    We have determined a value for the 1S0 neutron-neutron scattering length (ann) from high-precision measurements of time-of-flight spectra of neutrons from the H2(π-,nγ)n capture reaction. The measurements were done at the Los Alamos Meson Physics Facility by the E1286 Collaboration. The high spatial resolution of our γ-ray detector enabled us to make a detailed assessment of the systematic uncertainties in our techniques. The value obtained in the present work is ann=-18.63±0.10 (statistical) ± 0.44 (systematic) ± 0.30 (theoretical) fm. This result is consistent with previous determinations of ann from the π-d capture reaction. We found that the analysis of the data with calculations that use a relativistic phase-space factor gives a more negative value for ann by 0.33 fm over the analysis done using a nonrelativistic phase-space factor. Combining the present result with the previous ones from π-d capture gives ann=-18.63±0.27(expt)±0.30 fm (theory). For the first time the combined statistical and systematic experimental uncertainty in ann is smaller than the theoretical uncertainty and comparable to the uncertainty in the proton-proton 1S0 scattering length (app). This average value of ann when corrected for the magnetic-moment interaction of the two neutrons becomes -18.9 ± 0.4 fm, which is 1.6 ± 0.5 fm different from the recommended value of app, thereby confirming charge symmetry breaking at the 1% confidence level.

  2. Contact line extraction and length measurements in model sediments and sedimentary rocks.

    PubMed

    Rodriguez, Elena; Prodanović, Maša; Bryant, Steven L

    2012-02-15

    The mechanisms that govern the transport of colloids in the unsaturated zone of soils are still poorly understood, because of the complexity of processes that occur at pore scale. These mechanisms are of specific interest in quantifying water quality with respect to pathogen transport (e.g. Escherichia coli, Cryptosporidium) between the source (e.g. farms) and human users. Besides straining in pore throats and constrictions of smaller or equivalent size, the colloids can be retained at the interfaces between air, water, and grains. Theories competing to explain this mechanism claim that retention can be caused by adhesion at the air-water-interface (AWI) between sediment grains or by straining at the air-water-solid (AWS) contact line. Currently, there are no established methods for the estimation of pathogen retention in unsaturated media because of the intricate influence of AWI and AWS on transport and retention. What is known is that the geometric configuration and connectivity of the aqueous phase is an important factor in unsaturated transport. In this work we develop a computational method based on level set functions to identify and quantify the AWS contact line (in general the non-wetting-wetting-solid contact line) in any porous material. This is the first comprehensive report on contact line measurement for fluid configurations from both level-set method based fluid displacement simulation and imaged experiments. The method is applicable to any type of porous system, as long as the detailed pore scale geometry is available. We calculated the contact line length in model sediments (packs of spheres) as well as in real porous media, whose geometry is taken from high-resolution images of glass bead packs and sedimentary rocks. We observed a strong dependence of contact line length on the geometry of the sediment grains and the arrangement of the air and water phases. These measurements can help determine the relative contribution of the AWS line to pathogen

  3. Assessing Long-Term Wind Conditions by Combining Different Measure-Correlate-Predict Algorithms: Preprint

    SciTech Connect

    Zhang, J.; Chowdhury, S.; Messac, A.; Hodge, B. M.

    2013-08-01

    This paper significantly advances the hybrid measure-correlate-predict (MCP) methodology, enabling it to account for variations of both wind speed and direction. The advanced hybrid MCP method uses the recorded data of multiple reference stations to estimate the long-term wind condition at a target wind plant site. The results show that the accuracy of the hybrid MCP method is highly sensitive to the combination of the individual MCP algorithms and reference stations. It was also found that the best combination of MCP algorithms varies based on the length of the correlation period.

  4. The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast

    PubMed Central

    2011-01-01

    Background Surprisingly, in several multi-cellular eukaryotes optimal codon use correlates negatively with gene length. This contrasts with the expectation under selection for translational accuracy. While suggested explanations focus on variation in strength and efficiency of translational selection, it has rarely been noticed that the negative correlation is reported only in organisms whose optimal codons are biased towards codons that end with G or C (-GC). This raises the question whether forces that affect base composition - such as GC-biased gene conversion - contribute to the negative correlation between optimal codon use and gene length. Results Yeast is a good organism to study this as equal numbers of optimal codons end in -GC and -AT and one may hence compare frequencies of optimal GC- with optimal AT-ending codons to disentangle the forces. Results of this study demonstrate in yeast frequencies of GC-ending (optimal AND non-optimal) codons decrease with gene length and increase with recombination. A decrease of GC-ending codons along genes contributes to the negative correlation with gene length. Correlations with recombination and gene expression differentiate between GC-ending and optimal codons, and also substitution patterns support effects of GC-biased gene conversion. Conclusion While the general effect of GC-biased gene conversion is well known, the negative correlation of optimal codon use with gene length has not been considered in this context before. Initiation of gene conversion events in promoter regions and the presence of a gene conversion gradient most likely explain the observed decrease of GC-ending codons with gene length and gene position. PMID:21481245

  5. Spontaneous oscillation of tension and sarcomere length in skeletal myofibrils. Microscopic measurement and analysis.

    PubMed Central

    Anazawa, T; Yasuda, K; Ishiwata, S

    1992-01-01

    We have devised a simple method for measuring tension development of single myofibrils by micromanipulation with a pair of glass micro-needles. The tension was estimated from the deflection of a flexible needle under an inverted phase-contrast microscope equipped with an image processor, so that the tension development is always accompanied by the shortening of the myofibril (auxotonic condition) in the present setup. The advantage of this method is that the measurement of tension (1/30 s for time resolution and about 0.05 micrograms for accuracy of tension measurement; 0.05 microns as a spatial resolution for displacement of the micro-needle) and the observation of sarcomere structure are possible at the same time, and the technique to hold myofibrils, even single myofibrils, is very simple. This method has been applied to study the tension development of glycerinated skeletal myofibrils under the condition where spontaneous oscillation of sarcomeres is induced, i.e., the coexistence of MgATP, MgADP and inorganic phosphate without free Ca2+. Under this condition, we found that the tension of myofibrils spontaneously oscillates accompanied by the oscillation of sarcomere length with a main period of a few seconds; the period was lengthened and shortened with stretch and release of myofibrils. A possible mechanism of the oscillation is discussed. Images FIGURE 4 PMID:1600075

  6. Measuring telomere length and telomere dynamics in evolutionary biology and ecology

    PubMed Central

    Nussey, Daniel H; Baird, Duncan; Barrett, Emma; Boner, Winnie; Fairlie, Jennifer; Gemmell, Neil; Hartmann, Nils; Horn, Thorsten; Haussmann, Mark; Olsson, Mats; Turbill, Chris; Verhulst, Simon; Zahn, Sandrine; Monaghan, Pat

    2014-01-01

    Telomeres play a fundamental role in the protection of chromosomal DNA and in the regulation of cellular senescence. Recent work in human epidemiology and evolutionary ecology suggests adult telomere length (TL) may reflect past physiological stress and predict subsequent morbidity and mortality, independent of chronological age. Several different methods have been developed to measure TL, each offering its own technical challenges. The aim of this review is to provide an overview of the advantages and drawbacks of each method for researchers, with a particular focus on issues that are likely to face ecologists and evolutionary biologists collecting samples in the field or in organisms that may never have been studied in this context before. We discuss the key issues to consider and wherever possible try to provide current consensus view regarding best practice with regard to sample collection and storage, DNA extraction and storage, and the five main methods currently available to measure TL. Decisions regarding which tissues to sample, how to store them, how to extract DNA, and which TL measurement method to use cannot be prescribed, and are dependent on the biological question addressed and the constraints imposed by the study system. What is essential for future studies of telomere dynamics in evolution and ecology is that researchers publish full details of their methods and the quality control thresholds they employ. PMID:25834722

  7. Comparison axial length measurements from three biometric instruments in high myopia

    PubMed Central

    Wang, Xiao-Gang; Dong, Jing; Pu, Yu-Lan; Liu, Hui-Jun; Wu, Qiang

    2016-01-01

    AIM To compare the axial lengths (ALs) measured with Lenstar, IOLMaster and A-scan contact ultrasound (Ultrasound) in normal and high myopia (HM). METHODS Eighty-four normal eyes and 49 HM eyes were included. Three consecutive measurements were performed on each eye in the following order: Lenstar, IOLMaster, and Ultrasound. The repeatabilities of the AL measurements for each instrument were assessed by calculating the pooled coefficients of variation (CVs) of 18 eyes in each group. Comparisons between the HM and normal groups were made with independent sample t-tests. The inter-device agreements were evaluated with Bland-Altman analyses and paired two-tailed t-tests. RESULTS For normal group, the CVs of the AL measurements taken with the Lenstar, IOLMaster and Ultrasound were 0.001%, 0.01% and 0.14%, respectively. The corresponding CVs for the HM group were 0.005%, 0.02% and 0.15%, respectively. There was significant difference between the Lenstar and the IOLMaster in normal group (P=0.031) but not in HM group (P=0.100). In the two groups, the Lenstar and the IOLMaster produced higher values than did the Ultrasound (all P<0.001). All three instruments exhibited good agreement in terms of AL values. For the intraocular lens (IOL) power calculation using SRK II formula, the Lenstar and the IOLMaster showed 0.5 D higher than Ultrasound in both groups (all P<0.001). No significant difference existed between the Lenstar and the IOLMaster for the IOL power calculation in both normal (P=0.474) and HM group (P=0.103). CONCLUSION The three devices exhibited excellent intra-visit repeatabilities in the AL measurements. The AL and IOL power difference between partial coherence interferometry and ultrasound instruments should be noticed. PMID:27366691

  8. The Measurement and Correlates of Career Decision Making.

    ERIC Educational Resources Information Center

    Harren, Vincent A.; Kass, Richard A.

    This paper presents a theoretical framework for understanding career decision making (CDM); introduces an instrument, Assessment of Career Decision Making (ACDM) to measure CDM with college students; and presents correlational data on sex role and cognitive style factors hypothesized to influence CDM. The ACDM, designed to measure the Tiedeman and…

  9. Internalized Heterosexism: Measurement, Psychosocial Correlates, and Research Directions

    ERIC Educational Resources Information Center

    Szymanski, Dawn M.; Kashubeck-West, Susan; Meyer, Jill

    2008-01-01

    This article provides an integrated critical review of the literature on internalized heterosexism/internalized homophobia (IH), its measurement, and its psychosocial correlates. It describes the psychometric properties of six published measures used to operationalize the construct of IH. It also critically reviews empirical studies on correlates…

  10. Accuracy of axial length measurements from immersion B-scan ultrasonography in highly myopic eyes

    PubMed Central

    Yang, Qing-Hua; Chen, Bing; Peng, Guang-Hua; Li, Zhao-Hui; Huang, Yi-Fei

    2014-01-01

    AIM To evaluate the accuracy of axial length (AL) measurements obtained from immersion B-scan ultrasonography (immersion B-scan) for intraocular lens (IOL) power calculation in patients with high myopia and cataracts. METHODS Immersion B-scan, contact A-scan ultrasonography (contact A-scan), and the IOLMaster were used to preoperatively measure the AL in 102 eyes from 102 patients who underwent phacoemulsification and IOL implantation. Patients were divided into two groups according to the AL: one containing patients with 22 mm≤AL<26 mm(group A) and the other containing patients with AL≥26 mm (group B). The mean error (ME) was calculated from the difference between the AL measurement methods predicted refractive error and the actual postoperative refractive error. RESULTS In group A, ALs measured by immersion B-scan (23.48±1.15) didn't differ significantly from those measured by the IOLMaster (23.52±1.17) or from those by contact A-scan (23.38±1.20). In the same group, the standard deviation (SD) of the mean error (ME) of immersion B-scan (-0.090±0.397 D) didn't differ significantly from those of IOLMaster (-0.095±0.411 D) and contact A-scan (-0.099±0.425 D). In group B, ALs measured by immersion B-scan (27.97±2.21 mm) didn't differ significantly from those of the IOLMaster (27.86±2.18 mm), but longer than those measured by Contact A-scan (27.75±2.23 mm, P=0.009). In the same group, the standard deviation (SD) of the mean error (ME) of immersion B-scan (-0.635±0.157 D) didn't differ significantly from those of the IOLMaster (-0.679±0.359 D), but differed significantly from those of contact A-scan (-0.953±1.713 D, P=0.028). CONCLUSION Immersion B-scan exhibits measurement accuracy comparable to that of the IOLMaster, and is thus a good alternative in measuring AL in eyes with high myopia when the IOLMaster can't be used, and it is more accurate than the contact A-scan. PMID:24967188

  11. Statistical measures of Planck scale signal correlations in interferometers

    SciTech Connect

    Hogan, Craig J.; Kwon, Ohkyung

    2015-06-22

    A model-independent statistical framework is presented to interpret data from systems where the mean time derivative of positional cross correlation between world lines, a measure of spreading in a quantum geometrical wave function, is measured with a precision smaller than the Planck time. The framework provides a general way to constrain possible departures from perfect independence of classical world lines, associated with Planck scale bounds on positional information. A parametrized candidate set of possible correlation functions is shown to be consistent with the known causal structure of the classical geometry measured by an apparatus, and the holographic scaling of information suggested by gravity. Frequency-domain power spectra are derived that can be compared with interferometer data. As a result, simple projections of sensitivity for specific experimental set-ups suggests that measurements will directly yield constraints on a universal time derivative of the correlation function, and thereby confirm or rule out a class of Planck scale departures from classical geometry.

  12. Data on correlations between T cell subset frequencies and length of partial remission in type 1 diabetes.

    PubMed

    Narsale, Aditi; Moya, Rosita; Robertson, Hannah Kathryn; Davies, Joanna Davida

    2016-09-01

    Partial remission in patients newly diagnosed with type 1 diabetes is a period of good glucose control that can last from several weeks to over a year. The clinical significance of the remission period is that patients might be more responsive to immunotherapy if treated within this period. This article provides clinical data that indicates the level of glucose control and insulin-secreting β-cell function of each patient in the study at baseline (within 3 months of diagnosis), and at 3, 6, 9, 12, 18 and 24 months post-baseline. The relative frequency of immune cell subsets in the PBMC of each patient and the association between the frequency of immune cell subsets measured and length of remission is also shown. These data support the findings reported in the accompanying publication, "A pilot study showing associations between frequency of CD4+ memory cell subsets at diagnosis and duration of partial remission in type 1 diabetes" (Moya et al., 2016) [1], where a full interpretation, including biological relevance of the study can be found. PMID:27579340

  13. Application of Laser Correlation Spectroscopy for Measuring Virus Size.

    PubMed

    Nikiforov, V N; Vinogradov, S E; Ivanov, A V; Efremova, E V; Kalnina, L B; Bychenko, A B; Tentsov, Yu Yu; Manykin, A A

    2016-05-01

    Dynamic light scattering method or laser correlation spectroscopy was applied to evaluation of the size of viruses. We measured correlation functions of the light scattered by human immunodeficiency viruses (HIV) and hepatitis A viruses (HAV) and found that size of HIV-1 (subtype A and B) and HAV virions were 104 nm and 28 nm, respectively. Comparison of these findings with electron microscopy data for fixed samples of the same viruses showed good agreement of the results. PMID:27270934

  14. First Measurements of Pion Correlations by the PHENIX Experiment

    SciTech Connect

    Johnson, S C

    2001-04-11

    First identical-pion correlations measured at RHIC energies by PHENIX are presented. Two analyses with separate detectors, systematics, and statistics provide consistent results. The resulting HBT radii are moderately larger than those measured at lower energies. The k{sub t} dependence of the Bertsch-Pratt HBT radii is also similar to previous measures and is consistent with the conjecture of an expanding source.

  15. Analyzing complex networks through correlations in centrality measurements

    NASA Astrophysics Data System (ADS)

    Furlan Ronqui, José Ricardo; Travieso, Gonzalo

    2015-05-01

    Many real world systems can be expressed as complex networks of interconnected nodes. It is frequently important to be able to quantify the relative importance of the various nodes in the network, a task accomplished by defining some centrality measures, with different centrality definitions stressing different aspects of the network. It is interesting to know to what extent these different centrality definitions are related for different networks. In this work, we study the correlation between pairs of a set of centrality measures for different real world networks and two network models. We show that the centralities are in general correlated, but with stronger correlations for network models than for real networks. We also show that the strength of the correlation of each pair of centralities varies from network to network. Taking this fact into account, we propose the use of a centrality correlation profile, consisting of the values of the correlation coefficients between all pairs of centralities of interest, as a way to characterize networks. Using the yeast protein interaction network as an example we show also that the centrality correlation profile can be used to assess the adequacy of a network model as a representation of a given real network.

  16. Measuring short electron bunch lengths using coherent Smith-Purcell radiation

    DOEpatents

    Nguyen, D.C.

    1999-03-30

    A method is provided for directly determining the length of sub-picosecond electron bunches. A metallic grating is formed with a groove spacing greater than a length expected for the electron bunches. The electron bunches are passed over the metallic grating to generate coherent and incoherent Smith-Purcell radiation. The angular distribution of the coherent Smith-Purcell radiation is then mapped to directly deduce the length of the electron bunches. 8 figs.

  17. Measuring short electron bunch lengths using coherent smith-purcell radiation

    DOEpatents

    Nguyen, Dinh C.

    1999-01-01

    A method is provided for directly determining the length of sub-picosecond electron bunches. A metallic grating is formed with a groove spacing greater than a length expected for the electron bunches. The electron bunches are passed over the metallic grating to generate coherent and incoherent Smith-Purcell radiation. The angular distribution of the coherent Smith-Purcell radiation is then mapped to directly deduce the length of the electron bunches.

  18. Measuring bipartite quantum correlations of an unknown state.

    PubMed

    Silva, I A; Girolami, D; Auccaise, R; Sarthour, R S; Oliveira, I S; Bonagamba, T J; deAzevedo, E R; Soares-Pinto, D O; Adesso, G

    2013-04-01

    We report the experimental measurement of bipartite quantum correlations of an unknown two-qubit state. Using a liquid state Nuclear Magnetic Resonance setup and employing geometric discord, we evaluate the quantum correlations of a state without resorting to prior knowledge of its density matrix. The method is applicable to any 2 ⊗ d system and provides, in terms of number of measurements required, an advantage over full state tomography scaling with the dimension d of the unmeasured subsystem. The negativity of quantumness is measured as well for reference. We also observe the phenomenon of sudden transition of quantum correlations when local phase and amplitude damping channels are applied to the state. PMID:25166969

  19. Entanglement Measures for Single- and Multireference Correlation Effects.

    PubMed

    Boguslawski, Katharina; Tecmer, Pawel̷; Legeza, Örs; Reiher, Markus

    2012-11-01

    Electron correlation effects are essential for an accurate ab initio description of molecules. A quantitative a priori knowledge of the single- or multireference nature of electronic structures as well as of the dominant contributions to the correlation energy can facilitate the decision regarding the optimum quantum chemical method of choice. We propose concepts from quantum information theory as orbital entanglement measures that allow us to evaluate the single- and multireference character of any molecular structure in a given orbital basis set. By studying these measures we can detect possible artifacts of small active spaces. PMID:26296018

  20. Individual differences in allocation of funds in the dictator game associated with length of the arginine vasopressin 1a receptor RS3 promoter region and correlation between RS3 length and hippocampal mRNA.

    PubMed

    Knafo, A; Israel, S; Darvasi, A; Bachner-Melman, R; Uzefovsky, F; Cohen, L; Feldman, E; Lerer, E; Laiba, E; Raz, Y; Nemanov, L; Gritsenko, I; Dina, C; Agam, G; Dean, B; Bornstein, G; Ebstein, R P

    2008-04-01

    Human altruism is a widespread phenomenon that puzzled evolutionary biologists since Darwin. Economic games illustrate human altruism by showing that behavior deviates from economic predictions of profit maximization. A game that most plainly shows this altruistic tendency is the Dictator Game. We hypothesized that human altruistic behavior is to some extent hardwired and that a likely candidate that may contribute to individual differences in altruistic behavior is the arginine vasopressin 1a (AVPR1a) receptor that in some mammals such as the vole has a profound impact on affiliative behaviors. In the current investigation, 203 male and female university students played an online version of the Dictator Game, for real money payoffs. All subjects and their parents were genotyped for AVPR1a RS1 and RS3 promoter-region repeat polymorphisms. Parents did not participate in online game playing. As variation in the length of a repetitive element in the vole AVPR1a promoter region is associated with differences in social behavior, we examined the relationship between RS1 and RS3 repeat length (base pairs) and allocation sums. Participants with short versions (308-325 bp) of the AVPR1a RS3 repeat allocated significantly (likelihood ratio = 14.75, P = 0.001, df = 2) fewer shekels to the 'other' than participants with long versions (327-343 bp). We also implemented a family-based association test, UNPHASED, to confirm and validate the correlation between the AVPR1a RS3 repeat and monetary allocations in the dictator game. Dictator game allocations were significantly associated with the RS3 repeat (global P value: likelihood ratio chi(2) = 11.73, df = 4, P = 0.019). The association between the AVPR1a RS3 repeat and altruism was also confirmed using two self-report scales (the Bardi-Schwartz Universalism and Benevolence Value-expressive Behavior scales). RS3 long alleles were associated with higher scores on both measures. Finally, long AVPR1a RS3 repeats were associated with

  1. The comparison of the lengths and diameters of main bronchi measured from two-dimensional and three-dimensional images in the same patients

    PubMed Central

    Lee, Jeong Woo; Choi, Jin-Wook; Han, Young-Jin; Lee, Jun-Rae

    2014-01-01

    Background Recently, multi-planar reconstruction of the three-dimensional (3D) spiral chest CT scan has demonstrated superiority in the evaluation of the tracheobronchial tree. The goal of this study was to measure the lengths of the right and left main bronchi and their anteroposterior (AP) and transverse (TR) diameters using the 3D and two-dimensional (2D) images in the same adult respectively, and to evaluate the degree of correlation between them. Methods We measured the lengths of the right and left main bronchi from the carina to the first of their branches and the AP and TR diameters at the mid-portion of the right main bronchus and 2 cm below the carina in the left main bronchus. We determined the size of the left-sided double-lumen tube (DLT) based on the measured AP diameter of the left main bronchus from the 3D and 2D images, respectively. Results There was moderate correlation between the lengths of both main bronchi obtained from the 3D images and the 2D images, and between the AP diameter of the left main bronchus obtained from the 3D images and the 2D images. Same sized DLTs were estimated in 69% of the men and 34% of the women. Conclusions The lengths of the right and left main bronchi and their AP and TR diameters obtained from 3D images were not strongly correlated with those from 2D images. Therefore, a further study is needed to verify the superiority of 3D images in selecting the appropriate size of left-sided DLT. PMID:24729839

  2. Measurement of growing dynamical length scales and prediction of the jamming transition in a granular material

    NASA Astrophysics Data System (ADS)

    Keys, Aaron S.; Abate, Adam R.; Glotzer, Sharon C.; Durian, Douglas J.

    2007-04-01

    Supercooled liquids and dense colloidal suspensions exhibit anomalous behaviour known as `spatially heterogeneous dynamics' (SHD), which becomes increasingly pronounced as the system approaches the glass transition. Recently, the observation of SHD in confined granular packings under slow shear near the onset of jamming has bolstered speculation that the two transitions are related. Here, we report measurements of SHD in a system of air-driven granular beads, as a function of both density and effective temperature. On approach to jamming, the dynamics becomes progressively slower and more spatially heterogeneous. The rapid growth of timescales and dynamical length scales characterizing the heterogeneities can be described both by mode-coupling theory and the Vogel-Tammann-Fulcher (VTF) equation, such as in glass-forming liquids. The value of the control variable at the VTF transition coincides with point J (refs 9, 10), the random close-packed jamming density at which all motion ceases, in analogy to a zero-temperature ideal glass transition. Our findings demonstrate further universality of the jamming concept and provide a significant step forward in the quest for a unified theory of jamming in disparate systems.

  3. Constrained tension control of a tethered space-tug system with only length measurement

    NASA Astrophysics Data System (ADS)

    Wen, Hao; Zhu, Zheng H.; Jin, Dongping; Hu, Haiyan

    2016-02-01

    The paper presents a tension control law to stabilize the motions of a Tethered Space-Tug system during its deorbiting process by regulating the tension in the tether. The tension control law is designed on a basis of two straightforward ideas, i.e., the potential energy shaping and the damping injection. The law is expressed in an analytical feedback form in terms of only the tether length without the need of the feedback of full state information. Meanwhile, the requirements of measuring velocities are removed with the aid of a dynamic extension technique based on the feedback interconnection of Euler-Lagrange systems. The positive and bounded tension constraint is taken into consideration explicitly by including a pair of special saturation terms in the feedback control law. The relative motions of the space-tug and the debris are described with respect to a local non-inertial orbital frame of reference, whereas the orbital motion equations of the system are formulated in terms of the modified equinoctial elements of the orbit. Finally, the effectiveness of the proposed scheme is demonstrated via numerical case studies.

  4. Acoustic ship signature measurements by cross-correlation method.

    PubMed

    Fillinger, Laurent; Sutin, Alexander; Sedunov, Alexander

    2011-02-01

    Cross-correlation methods were applied for the estimation of the power spectral density and modulation spectrum of underwater noise generated by moving vessels. The cross-correlation of the signal from two hydrophones allows the separation of vessel acoustic signatures in a busy estuary. Experimental data recorded in the Hudson River are used for demonstration that cross-correlation method measured the same ship noise and ship noise modulation spectra as conventional methods. The cross-correlation method was then applied for the separation of the acoustic signatures of two ships present simultaneously. Presented methods can be useful for ship traffic monitoring and small ship classification, even in noisy harbor environments. PMID:21361436

  5. Non-Markovianity measure using two-time correlation functions

    NASA Astrophysics Data System (ADS)

    Ali, Md. Manirul; Lo, Ping-Yuan; Tu, Matisse Wei-Yuan; Zhang, Wei-Min

    2015-12-01

    We investigate non-Markovianity measure using two-time correlation functions for open quantum systems. We define non-Markovianity measure as the difference between the exact two-time correlation function and the one obtained from quantum regression theorem in the Born-Markov approximation. Such non-Markovianity can easily be measured in experiments. We found that the non-Markovianity dynamics in different time scale crucially depends on the system-environment coupling strength and other physical parameters such as the initial temperature of the environment and the initial state of the system. In particular, we obtain the short-time and long-time behaviors of non-Markovianity for different spectral densities. We find that the thermal fluctuation always reduce the non-Markovian memory effect. Also, the non-Markovianity measure shows nontrivial initial state dependence in different time scales.

  6. Effective lactation yield: A measure to compare milk yield between cows with different dry period lengths.

    PubMed

    Kok, A; van Middelaar, C E; Engel, B; van Knegsel, A T M; Hogeveen, H; Kemp, B; de Boer, I J M

    2016-04-01

    To compare milk yields between cows or management strategies, lactations are traditionally standardized to 305-d yields. The 305-d yield, however, gives no insight into the combined effect of additional milk yield before calving, decreased milk yield after calving, and a possible shorter calving interval in the case of a shortened dry period. We aimed to develop a measure that would enable the comparison of milk yield between cows with different dry period (DP) lengths. We assessed the importance of accounting for additional milk yield before calving and for differences in calving interval. The 305-d yield was compared with a 365-d yield, which included additional milk yield in the 60 d before calving. Next, an effective lactation yield was computed, defined as the daily yield from 60d before calving to 60 d before the next calving, to account for additional milk yield before calving and for differences in calving interval. Test-day records and drying-off dates of 15 commercial farms were used to compute the 305-d, 365-d, and effective lactation yields for individual cows. We analyzed 817 second-parity lactations preceded by no DP, a short DP (20 to 40 d), or a conventional DP (49 to 90 d). Compared with cows with a conventional DP, the 305-d yield of cows with no DP was 7.0 kg of fat- and protein-corrected milk (FPCM) per day lower, and the 305-d yield of cows with a short DP was 2.3 kg of FPCM per day lower. Including additional milk yield before calving in the 365-d yield reduced this difference to 3.4 kg of FPCM per cow per day for cows with no DP and to 0.9 kg of FPCM per cow per day for cows with a short DP. Compared with cows with a conventional DP, median days open were reduced by 25d for cows with no DP and by 18d for cows with a short DP. Accounting for these differences in calving interval in the effective lactation yield further decreased yield reductions for cows with no DP or a short DP by 0.3 kg of FPCM per cow per day. At the herd level, estimated

  7. Measurement of coherence length and incoherent source size of hard x-ray undulator beamline at Pohang Light Source-II

    SciTech Connect

    Park, So Yeong; Hong, Chung Ki; Lim, Jun

    2014-04-15

    We measured the spatial coherence length and incoherent source size of a hard x-ray undulator beamline at Pohang Light Source-II, the stored electron energy of which has been increased from 2.5 GeV to 3 GeV. The coherence length was determined by single-slit measurement of the visibility of the Fresnel diffraction pattern. The correlated incoherent source size was cross-checked for three different optics: the single slit, beryllium parabolic compound refractive lenses, and the Fresnel zone plate. We concluded that the undulator beamline has an effective incoherent source size (FWHM) of 540 μm (horizontal) × 50 μm (vertical)

  8. Measurement of minority carrier diffusion lengths in GaAs nanowires by a nanoprobe technique

    NASA Astrophysics Data System (ADS)

    Darbandi, A.; Watkins, S. P.

    2016-07-01

    Minority carrier diffusion lengths in both p-type and n-type GaAs nanowires were studied using electron beam induced current by means of a nanoprobe technique without lithographic processing. The diffusion lengths were determined for Au/GaAs rectifying junctions as well as axial p-n junctions. By incorporating a thin lattice-matched InGaP passivating shell, a 2-fold enhancement in the minority carrier diffusion lengths and one order of magnitude reduction in the surface recombination velocity were achieved.

  9. Two Point Space-Time Correlation of Density Fluctuations Measured in High Velocity Free Jets

    NASA Technical Reports Server (NTRS)

    Panda, Jayanta

    2006-01-01

    Two-point space-time correlations of air density fluctuations in unheated, fully-expanded free jets at Mach numbers M(sub j) = 0.95, 1.4, and 1.8 were measured using a Rayleigh scattering based diagnostic technique. The molecular scattered light from two small probe volumes of 1.03 mm length was measured for a completely non-intrusive means of determining the turbulent density fluctuations. The time series of density fluctuations were analyzed to estimate the integral length scale L in a moving frame of reference and the convective Mach number M(sub c) at different narrow Strouhal frequency (St) bands. It was observed that M(sub c) and the normalized moving frame length scale L*St/D, where D is the jet diameter, increased with Strouhal frequency before leveling off at the highest resolved frequency. Significant differences were observed between data obtained from the lip shear layer and the centerline of the jet. The wave number frequency transform of the correlation data demonstrated progressive increase in the radiative part of turbulence fluctuations with increasing jet Mach number.

  10. Reliability and accuracy of an automated tracking algorithm to measure controlled passive and active muscle fascicle length changes from ultrasound.

    PubMed

    Gillett, Jarred G; Barrett, Rod S; Lichtwark, Glen A

    2013-01-01

    Manual tracking of muscle fascicle length changes from ultrasound images is a subjective and time-consuming process. The purpose of this study was to assess the repeatability and accuracy of an automated algorithm for tracking fascicle length changes in the medial gastrocnemius (MG) muscle during passive length changes and active contractions (isometric, concentric and eccentric) performed on a dynamometer. The freely available, automated tracking algorithm was based on the Lucas-Kanade optical flow algorithm with an affine optic flow extension, which accounts for image translation, dilation, rotation and shear between consecutive frames of an image sequence. Automated tracking was performed by three experienced assessors, and within- and between-examiner repeatability was computed using the coefficient of multiple determination (CMD). Fascicle tracking data were also compared with manual digitisation of the same image sequences, and the level of agreement between the two methods was calculated using the coefficient of multiple correlation (CMC). The CMDs across all test conditions ranged from 0.50 to 0.93 and were all above 0.98 when recomputed after the systematic error due to the estimate of the initial fascicle length on the first ultrasound frame was removed from the individual fascicle length waveforms. The automated and manual tracking approaches produced similar fascicle length waveforms, with an overall CMC of 0.88, which improved to 0.94 when the initial length offset was removed. Overall results indicate that the automated fascicle tracking algorithm was a repeatable, accurate and time-efficient method for estimating fascicle length changes of the MG muscle in controlled passive and active conditions. PMID:22235878

  11. Recovering refractive index correlation function from measurement of tissue scattering phase function (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Rogers, Jeremy D.

    2016-03-01

    Numerous methods have been developed to quantify the light scattering properties of tissue. These properties are of interest in diagnostic and screening applications due to sensitivity to changes in tissue ultrastructure and changes associated with disease such as cancer. Tissue is considered a weak scatterer because that the mean free path is much larger than the correlation length. When this is the case, all scattering properties can be calculated from the refractive index correlation function Bn(r). Direct measurement of Bn(r) is challenging because it requires refractive index measurement at high resolution over a large tissue volume. Instead, a model is usually assumed. One particularly useful model, the Whittle-Matern function includes several realistic function types such as mass fractal and exponential. Optical scattering properties for weakly scattering media can be determined analytically from Bn(r) by applying the Rayleigh-Gans-Debye (RGD) or Born Approximation, and so measured scattering properties are used to fit parameters of the model function. Direct measurement of Bn(r) would provide confirmation that the function is a good representation of tissue or help in identifying the length scale at which changes occur. The RGD approximation relates the scattering phase function to the refractive index correlation function through a Fourier transform. This can be inverted without approximation, so goniometric measurement of the scattering can be converted to Bn(r). However, geometric constraints of the measurement of the phase function, angular resolution, and wavelength result in a band limited measurement of Bn(r). These limits are discussed and example measurements are described.

  12. Correlation of Spatially Filtered Dynamic Speckles in Distance Measurement Application

    SciTech Connect

    Semenov, Dmitry V.; Nippolainen, Ervin; Kamshilin, Alexei A.; Miridonov, Serguei V.

    2008-04-15

    In this paper statistical properties of spatially filtered dynamic speckles are considered. This phenomenon was not sufficiently studied yet while spatial filtering is an important instrument for speckles velocity measurements. In case of spatial filtering speckle velocity information is derived from the modulation frequency of filtered light power which is measured by photodetector. Typical photodetector output is represented by a narrow-band random noise signal which includes non-informative intervals. Therefore more or less precious frequency measurement requires averaging. In its turn averaging implies uncorrelated samples. However, conducting research we found that correlation is typical property not only of dynamic speckle patterns but also of spatially filtered speckles. Using spatial filtering the correlation is observed as a response of measurements provided to the same part of the object surface or in case of simultaneously using several adjacent photodetectors. Found correlations can not be explained using just properties of unfiltered dynamic speckles. As we demonstrate the subject of this paper is important not only from pure theoretical point but also from the point of applied speckle metrology. E.g. using single spatial filter and an array of photodetector can greatly improve accuracy of speckle velocity measurements.

  13. Rheology of fluids measured by correlation force spectroscopy

    NASA Astrophysics Data System (ADS)

    Radiom, Milad; Robbins, Brian; Honig, Christopher D. F.; Walz, John Y.; Paul, Mark R.; Ducker, William A.

    2012-04-01

    We describe a method, correlation force spectrometry (CFS), which characterizes fluids through measurement of the correlations between the thermally stimulated vibrations of two closely spaced micrometer-scale cantilevers in fluid. We discuss a major application: measurement of the rheological properties of fluids at high frequency and high spatial resolution. Use of CFS as a rheometer is validated by comparison between experimental data and finite element modeling of the deterministic ring-down of cantilevers using the known viscosity of fluids. The data can also be accurately fitted using a harmonic oscillator model, which can be used for rapid rheometric measurements after calibration. The method is non-invasive, uses a very small amount of fluid, and has no actively moving parts. It can also be used to analyze the rheology of complex fluids. We use CFS to show that (non-Newtonian) aqueous polyethylene oxide solution can be modeled approximately by incorporating an elastic spring between the cantilevers.

  14. Measurement of electrostriction in bone using digital image correlation

    NASA Astrophysics Data System (ADS)

    Xu, Lianyun; Hou, Zhende; Fu, Donghui; Yang, Lei; Yi, Weitian; Kang, Huimin

    2015-02-01

    The electromechanical properties of bone may play roles in the growth of bone tissue. The electrostriction effect of bone, which is one of the electromechanical properties of bone, was investigated using the digital image correlation technique (DIC). The advantage of using DIC is that the light beam used for the displacement measurement does not interfere with the electric field exerted on the bone specimen. To measure the bending deflections of a bone cantilever in an electric field, the displacement of the free end surface of the cantilever was measured using the image correlation technique. The experimental results show that the bending direction of the bone cantilevers is independent of the electric field direction and that the bending deflections are proportional to the square of the applied voltages. The attractive force between the charges on the electrode and the unlike charges in the specimen can be equivalent to a uniform distribution load regardless of the thickness of the bone specimen.

  15. Optimizing quantum correlation dynamics by weak measurement in dissipative environment

    NASA Astrophysics Data System (ADS)

    Du, Shao-Jiang; Xia, Yun-Jie; Duan, De-Yang; Zhang, Lu; Gao, Qiang

    2015-04-01

    We investigate the protection of quantum correlations of two qubits in independent vacuum reservoirs by means of weak measurements. It is found that the weak measurement can reduce the amount of quantum correlation for one type of initial state at the beginning in a non-Markovian environment and meanwhile it can reduce the occurrence time of entanglement sudden death (ESD) in the process of time evolution. In a Markovian environment, the quantum entanglements of the two kinds of initial states decay rapidly and the weak measurement can further weaken the quantum entanglement, therefore in this case the entanglement cannot be optimized in the evolution process. Project supported by the National Natural Science Foundation of China (Grant Nos. 61178012 and No.11147019).

  16. Axial length measurements before and after removal of silicone oil: a new method to correct the axial length of silicone-filled eyes for optical biometry.

    PubMed

    Wang, Kai; Yuan, Meng-Ke; Jiang, Yan-Rong; Bao, Yong-Zhen; Li, Xiao-Xin

    2009-07-01

    A total of 67 eyes of 67 patients that have undergone vitrectomy and silicone oil tamponade for rhegmatogenous retinal detachment were included in this prospective clinical study. We measured the axial length (AL) and the anterior chamber depth (ACD) with A-mode ultrasonography and IOL Master before and after removal of silicone oil. Phase refractive indices of silicone oil at different wavelengths from 400 nm to 1000 nm were measured with an Abbe refractometer and a series of equations were derived to adjust the AL values obtained with the IOL Master in silicone-filled eyes. The instruments showed good agreement between the AL values measured before and after removal of silicone oil. The ACD values obtained with A-mode ultrasonography were lower than the values obtained with the IOL Master (p < 0.01). The AL values obtained with the IOL Master after removal of silicone oil were lower than the values obtained preoperatively (p < 0.01). The AL values obtained with the IOL Master after adjustment are more accurate than A-mode ultrasonography in silicone-filled eyes. PMID:19523089

  17. Correlation of chain length compatibility and surface properties of mixed foaming agents with fluid displacement efficiency and effective air mobility in porous media

    SciTech Connect

    Sharma, M.K.; Bringham, W.E.; Shah, D.O.

    1984-05-01

    The effects of chain length compatibility and surface properties of mixed foaming agents on fluid displacement efficiency and effective air mobility in porous media were investigated. Sodium dodecyl sulfate (C/sub 12/H/sub 25/SO/sub 4/Na) and various alkyl alcohols (e.g., C/sub 8/OH,C/sub 10/OH,C/sub 12/OH,C/sub 14/OH, and C/sub 16/OH) were used as mixed foaming agents. It was observed that the surface properties of surfactant solutions and flow behavior of foams through porous media were influenced by the chain length compatibility of the surfactant molecules. The increase in the length of porous media improved fluid displacement efficiency while breakthrough time per unit length decreased slightly with increase in the length of porous media. For mixed surfactant systems, a minimum in surface tension, a maximum in surface viscosity, a minimum in bubble size, a maximum in breakthrough time, a maximum in fluid displacement efficiency, and a minimum in effective air mobility were observed when the two components of the surfactant system had the same chain length. These results indicate that the surface properties of foaming solutions and molecular packing at interfaces exhibit a striking correlation with breakthrough time, fluid displacement efficiency, and effective air mobility in porous media.

  18. Neural Correlates of Temporal Auditory Processing in Developmental Dyslexia during German Vowel Length Discrimination: An fMRI Study

    ERIC Educational Resources Information Center

    Steinbrink, Claudia; Groth, Katarina; Lachmann, Thomas; Riecker, Axel

    2012-01-01

    This fMRI study investigated phonological vs. auditory temporal processing in developmental dyslexia by means of a German vowel length discrimination paradigm (Groth, Lachmann, Riecker, Muthmann, & Steinbrink, 2011). Behavioral and fMRI data were collected from dyslexics and controls while performing same-different judgments of vowel duration in…

  19. Correlation techniques and measurements of wave-height statistics

    NASA Technical Reports Server (NTRS)

    Guthart, H.; Taylor, W. C.; Graf, K. A.; Douglas, D. G.

    1972-01-01

    Statistical measurements of wave height fluctuations have been made in a wind wave tank. The power spectral density function of temporal wave height fluctuations evidenced second-harmonic components and an f to the minus 5th power law decay beyond the second harmonic. The observations of second harmonic effects agreed very well with a theoretical prediction. From the wave statistics, surface drift currents were inferred and compared to experimental measurements with satisfactory agreement. Measurements were made of the two dimensional correlation coefficient at 15 deg increments in angle with respect to the wind vector. An estimate of the two-dimensional spatial power spectral density function was also made.

  20. Correlative measurement opportunities between ATLAS-1 and UARS experiments

    NASA Technical Reports Server (NTRS)

    Harrison, Edwin F.; Denn, Fred M.; Gibson, Gary G.

    1992-01-01

    The first ATmospheric Laboratory for Applications and Science (ATLAS-1) mission was flown aboard the Space Shuttle from March 24 to April 2, 1992. The ATLAS-1 instruments provided a large number of measurements which were coincident with observations from experiments on the Upper Atmosphere Research Satellite (UARS). During the ATLAS-1 mission, simulations were performed to predict when and where coincident measurements between ATLAS and UARS instruments would occur. These predictions were used to develop instrument operation schedules to maximize the correlative opportunities between the two satellites. Results of the simulations provide valuable information for the ATLAS and UARS scientists to compare measurements between various instruments on the two satellites.

  1. Behavioral and neurophysiological correlates of episodic coding, proactive interference, and list length effects in a running span verbal working memory task.

    PubMed

    Postle, B R; Berger, J S; Goldstein, J H; Curtis, C E; D'Esposito, M

    2001-03-01

    Updating refers to (1) discarding items from, (2) repositioning items in, and (3) adding items to a running working memory span. Our behavioral and fMRI experiments varied three factors: trial length, proactive interference (PI), and group integrity. Group integrity reflected whether the grouping of items at the encoding stage was violated at discarding. Behavioral results were consistent with the idea that updating processes have a relatively short refractory period and may not fatigue, and they revealed that episodic information about group context is encoded automatically in working memory stimulus representations. The fMRI results did not show evidence that updating requirements in a task recruit executive control processes other than those supporting performance on nonupdating trials. They did reveal an item-accumulation effect, in which signal increased monotonically with the number of items presented during the trial, despite the insensitivity of behavioral measures to this factor. Behavioral and fMRI correlates of PI extended previous results and rejected an alternative explanation of PI effects in working memory. PMID:12467100

  2. Which Anthropometric Measure Best Correlates with Neonatal Fat Mass at Birth?

    PubMed

    Dubnov-Raz, Gal; Gal, Moran; Landau-Helman, Yeela; Biderman, Lihi; Nir, Romy; Maayan-Metzger, Ayala

    2016-07-01

    Objective Body composition provides additional information than weight alone. There is currently no accepted anthropometric measure of adiposity in infants, yet weight and length data allow calculations of a wide array of indices. The study objective was to identify the anthropometric index which best correlates with neonatal adiposity, by examining the associations between neonatal fat mass and several anthropometric indices of newborn infants. Study Design The sum of skinfolds (SSF), birth weight, and birth length were measured in 94 healthy infants (58% males) born at term to healthy mothers. Several anthropometric indices were calculated, and their relationship with SSF was assessed using linear regression adjusting for gestational age and sex. Results SSF at birth was significantly higher in females compared with males (20.7 ± 3.3 vs. 18.8 ± 4.1 mm, p = 0.019). Birth weight, birth weight-for-gestational-age percentile, birth weight percentile, and weight/length ratio had the highest associations with SSF, yet R (2) values were very low, ranging from 16 to 18%. Body mass index (BMI), BMI percentile, ponderal index, and the symmetry index had even lower associations. Conclusion No anthropometric measure can confidently assess fat mass in infants at birth, in accordance with previous research. When body composition data are needed, they should be directly measured. PMID:26906178

  3. Reliability-guided digital image correlation for image deformation measurement

    SciTech Connect

    Pan Bing

    2009-03-10

    A universally applicable reliability-guided digital image correlation (DIC) method is proposed for reliable image deformation measurement. The zero-mean normalized cross correlation (ZNCC) coefficient is used to identify the reliability of the point computed. The correlation calculation begins with a seed point and is then guided by the ZNCC coefficient. That means the neighbors of the point with the highest ZNCC coefficient in a queue for computed points will be processed first. Thus the calculation path is always along the most reliable direction, and possible error propagation of the conventional DIC method can be avoided. The proposed novel DIC method is universally applicable to the images with shadows, discontinuous areas, and deformation discontinuity. Two image pairs were used to evaluate the performance of the proposed technique, and the successful results clearly demonstrate its robustness and effectiveness.

  4. Shot noise measurement in a strongly correlated material

    NASA Astrophysics Data System (ADS)

    Zhou, Panpan; Hardy, Will; Cho, Ethan; Cybart, Shane; Dynes, Robert; Natelson, Douglas

    In strongly correlated materials, the motion of an electron is strongly affected by interactions with other electrons, leading to many interesting phenomena including metal-insulator transitions, colossal magnetoresistance, and high temperature superconductivity. Shot noise is one experimental probe for electronic correlations beyond simple electronic transport. Shot noise, which originates from the discrete nature of the charge-carrying particles, can be strongly affected by electronic correlations. Here we report initial shot noise measurements in tunnel junctions prepared from a YBa2Cu3O7-x film sample, with nanoscale junctions written by focused helium ion beam. We will discuss a comparison of the shot noise between the YBCO film sample and standard tunnel junctions, as a function of temperature and bias, and the implications of these results.

  5. Correlation Between NDE Measurements and Elongation of Aluminum

    SciTech Connect

    Thompson, R. Bruce; Margetan, Frank J.; Nakagawa, Norio; Haldipur, Pranaam

    2007-03-21

    Complex aluminum forgings can have engineering properties which vary with position due to changes in the underlying local metal microstructure. Consequently, the material properties may be in compliance with production requirements in some regions of the forging, but out of compliance in others. One conical Al-7050 forging of interest was found to have elongation properties which failed required tests in certain regions. NDE measurements sensitive to microstructural changes were carried out to search for correlations with elongation properties. The results of a set of initial feasibility experiments will be reported. Both ultrasonic and eddy current NDE methods were used, with the goal being to determine which properties were sensitive to the elongation. Ultrasonic testing included the measurement of longitudinal and shear-wave velocity, longitudinal wave attenuation, and longitudinal and shear-wave backscattered grain noise. All tests were performed with the sonic beam entering through the coupon face that would be adjacent to the outer surface of the forging. Only modest differences in wave speed and attenuation values were seen among the suite of coupons, but significant differences were seen in backscattered noise levels. These appeared to indicate changes in grain structure but only exhibited partial correlation with elongation. The eddy current measurements were designed to be sensitive to the electrical resistivity. Included were a number of measurement configurations and frequencies. The signals exhibited a significant correlation with elongation.

  6. Non-contact measurement of linear thermal expansion coefficients of solid materials by infrared image correlation

    NASA Astrophysics Data System (ADS)

    Montanini, R.; Freni, F.

    2014-01-01

    A new non-contact optical method (IIC, infrared image correlation) for the determination of the coefficients of thermal expansion of solid materials is presented. The proposed method is based on performing a digital image correlation between thermal images recorded at different temperatures by means of an infrared camera. It allows the coefficient of thermal expansion of both isotropic and anisotropic solid materials to be determined by measuring simultaneously the fractional increase in length and the actual thermal field over a small region of interest in which a dual-emissivity stochastic speckle pattern has been created. The results reported in this paper prove the effectiveness of the proposed method that can be applied either to carry out reference measurements in laboratory or to evaluate thermal stresses and strains on structural components in-field.

  7. Digital correlator for the portable channel prober measurement instrument

    NASA Astrophysics Data System (ADS)

    Peo, George E., Jr.

    1987-12-01

    This document describes a Digital Correlator for the Portable Channel Prober Measurement Instrument being developed by the Naval Research Laboratory for use in experiments designed to characterize high frequency (HF) radio channels. This Digital Correlator is a digital signal processor designed and constructed by Stow Computer, 111 old Bolton Road, Stow, MA 01775, (617/508) 897-6838. Two Digital Correlators are integrated into the existing Digital Pre-processor to make a Portable Wideband HF Channel Analyzer. The Portable Wideband HF Channel Analyzer will be located at the receiving site of the channel probing experiment and is situated between the coherent radio receiver and the microcomputer used for data recording and analysis. The Portable Wideband HF Channel Analyzer computes the delay power spectrum of the received waveform. The in-phase and quadrature outputs of the receiver are sampled and converted to digital values by the Analog to Digital Converter, integrated by the Integrator, and correlated with a stored replica of the transmitted waveform by two Digital Correlators. The resulting tap gains are then read by the system microcomputer using the microcomputer interface.

  8. Correlating Function and Imaging Measures of the Medial Longitudinal Fasciculus

    PubMed Central

    Sakaie, Ken; Takahashi, Masaya; Remington, Gina; Wang, Xiaofeng; Conger, Amy; Conger, Darrel; Dimitrov, Ivan; Jones, Stephen; Frohman, Ashley; Frohman, Teresa; Sagiyama, Koji; Togao, Osamu

    2016-01-01

    Objective To test the validity of diffusion tensor imaging (DTI) measures of tissue injury by examining such measures in a white matter structure with well-defined function, the medial longitudinal fasciculus (MLF). Injury to the MLF underlies internuclear ophthalmoparesis (INO). Methods 40 MS patients with chronic INO and 15 healthy controls were examined under an IRB-approved protocol. Tissue integrity of the MLF was characterized by DTI parameters: longitudinal diffusivity (LD), transverse diffusivity (TD), mean diffusivity (MD) and fractional anisotropy (FA). Severity of INO was quantified by infrared oculography to measure versional disconjugacy index (VDI). Results LD was significantly lower in patients than in controls in the medulla-pons region of the MLF (p < 0.03). FA was also lower in patients in the same region (p < 0.0004). LD of the medulla-pons region correlated with VDI (R = -0.28, p < 0.05) as did FA in the midbrain section (R = 0.31, p < 0.02). Conclusions This study demonstrates that DTI measures of brain tissue injury can detect injury to a functionally relevant white matter pathway, and that such measures correlate with clinically accepted evaluation indices for INO. The results validate DTI as a useful imaging measure of tissue integrity. PMID:26800522

  9. Correlations between LDEX Measurements and the Lunar Plasma Environment

    NASA Astrophysics Data System (ADS)

    Szalay, Jamey; Horanyi, Mihaly; Poppe, Andrew; Halekas, Jasper

    2014-05-01

    The Lunar Dust Experiment (LDEX) aboard the Lunar Atmosphere and Dust Environment Explorer (LADEE) is an impact ionization dust detector capable of measuring the mass of sub-micron sized dust grains above the lunar surface. LDEX can also search for the putative population of grains with radii on the order of ~ 0.1 μm lofted over the terminator regions by measuring the collective current of dust grains that are below the detection threshold for single impacts. This current, intended to measure the collective impact plasma from multiple small grain impacts, has also shown considerable correlations with plasma measurements from the ARTEMIS (Acceleration, Reconnection, Turbulence, & Electrodynamics of Moon's Interaction with the Sun) mission. Through LADEE's many orbits, LDEX sees time periods with very low variability, having almost no activity as well as periods with very high variability. Since this type of high activity is also observed in anti-ram pointing measurements, much of this current cannot be explained by collections of small dust grain impacts. Given this, comparisons to ARTEMIS data provide a promising way to explain such measurements. This presentation will focus on the correlations between LDEX and ARTEMIS data.

  10. Length of psychiatric hospitalization is correlated with CYP2D6 functional status in inpatients with major depressive disorder

    PubMed Central

    Ruaño, Gualberto; Szarek, Bonnie L; Villagra, David; Gorowski, Krystyna; Kocherla, Mohan; Seip, Richard L; Goethe, John W; Schwartz, Harold I

    2016-01-01

    Aim This study aimed to determine the effect of the CYP2D6 genotype on the length of hospitalization stay for patients treated for major depressive disorder. Methods A total of 149 inpatients with a diagnosis of major depressive disorder at the Institute of Living, Hartford Hospital (CT, USA), were genotyped to detect altered alleles in the CYP2D6 gene. Prospectively defined drug metabolism indices (metabolic reserve, metabolic alteration and allele alteration) were determined quantitatively and assessed for their relationship to length of hospitalization stay. Results Hospital stay was significantly longer in deficient CYP2D6 metabolizers (metabolic reserve <2) compared with functional or suprafunctional metabolizers (metabolic reserve ≥2; 7.8 vs 5.7 days, respectively; p = 0.002). Conclusion CYP2D6 enzymatic functional status significantly affected length of hospital stay, perhaps due to reduced efficacy or increased side effects of the medications metabolized by the CYP2D6 isoenzyme. Functional scoring of CYP2D6 alleles may have a substantial impact on the quality of care, patient satisfaction and the economics of psychiatric treatment. PMID:23734807

  11. Measurement and correlation of jet fuel viscosities at low temperatures

    NASA Technical Reports Server (NTRS)

    Schruben, D. L.

    1985-01-01

    Apparatus and procedures were developed to measure jet fuel viscosity for eight current and future jet fuels at temperatures from ambient to near -60 C by shear viscometry. Viscosity data showed good reproducibility even at temperatures a few degrees below the measured freezing point. The viscosity-temperature relationship could be correlated by two linear segments when plotted as a standard log-log type representation (ASTM D 341). At high temperatures, the viscosity-temperature slope is low. At low temperatures, where wax precipitation is significant, the slope is higher. The breakpoint between temperature regions is the filter flow temperature, a fuel characteristic approximated by the freezing point. A generalization of the representation for the eight experimental fuels provided a predictive correlation for low-temperature viscosity, considered sufficiently accurate for many design or performance calculations.

  12. Performance of a correlator filter in betatron tune measurements and damping on the NSLS booster

    SciTech Connect

    Galayda, J.

    1985-01-01

    A ''compensated correlator filter'', described by Kramer, et al. has been used for measurement and damping of betatron oscillations in the NSLS booster. The filter consists of a zero-degree power splitter, a 180-degree splitter, a length of 7/8'' air dielectric coaxial cable, and a short length of RG-58 cable. Connected to a beam position monitor, the output of the filter is proportional to the difference in transverse position of each bunch on subsequent turns. The useful bandwidth of the filter for damping rigid bunch oscillations extends from 10 MHz to 250 MHz, in contrast with the gigahertz bandwidth requirements for stochastic cooling, for which the filter was originally proposed. Attenuation of all rotation harmonics in this bandwidth is 40 to 60 dB.

  13. The role of multiparticle correlations and Cooper pairing in the formation of molecules in an ultracold gas of Fermi atoms with a negative scattering length

    SciTech Connect

    Babichenko, V. S. Kagan, Yu.

    2012-11-15

    The influence of multiparticle correlation effects and Cooper pairing in an ultracold Fermi gas with a negative scattering length on the formation rate of molecules is investigated. Cooper pairing is shown to cause the formation rate of molecules to increase, as distinct from the influence of Bose-Einstein condensation in a Bose gas on this rate. This trend is retained in the entire range of temperatures below the critical one.

  14. A Nondestructive Method for Measuring the RMS Length of Charge Bunches Using the Wake Field Radiation Spectrum

    SciTech Connect

    Shchelkunov, S.V.; Marshall, T.C.; Hirshfield, J.L.; LaPointe, M.A.

    2004-12-07

    We report progress in the development of a nondestructive technique to measure bunch rms-length in the psec range and below, and eventually in the fsec range, by measuring the high-frequency spectrum of wake field radiation which is caused by the passage of a relativistic electron bunch through a channel surrounded by a dielectric. We demonstrate both experimentally and numerically that the generated spectrum is determined by the bunch rms-length, while the choice of the axial and longitudinal charge distribution is not important. Measurement of the millimeter-wave spectrum will determine the bunch rms-length in the psec range. This has been done using a series of calibrated mesh filters and the charge bunches produced by the 50MeV rf linac system at ATF, Brookhaven. We have developed the analysis of the factors crucial for achieving good accuracy in this measurement, and find the experimental data are fully understood by the theory. We point out that this technique also may be used for measuring fsec bunch lengths, using a prepared planar wake field microstructure.

  15. Measuring the Hydrodynamic Size of Nanoparticles Using Fluctuation Correlation Spectroscopy

    NASA Astrophysics Data System (ADS)

    Dominguez-Medina, Sergio; Chen, Sishan; Blankenburg, Jan; Swanglap, Pattanawit; Landes, Christy F.; Link, Stephan

    2016-05-01

    Fluctuation correlation spectroscopy (FCS) is a well-established analytical technique traditionally used to monitor molecular diffusion in dilute solutions, the dynamics of chemical reactions, and molecular processes inside living cells. In this review, we present the recent use of FCS for measuring the size of colloidal nanoparticles in solution. We review the theoretical basis and experimental implementation of this technique and its advantages and limitations. In particular, we show examples of the use of FCS to measure the size of gold nanoparticles, monitor the rotational dynamics of gold nanorods, and investigate the formation of protein coronas on nanoparticles.

  16. Measuring the Hydrodynamic Size of Nanoparticles Using Fluctuation Correlation Spectroscopy.

    PubMed

    Dominguez-Medina, Sergio; Chen, Sishan; Blankenburg, Jan; Swanglap, Pattanawit; Landes, Christy F; Link, Stephan

    2016-05-27

    Fluctuation correlation spectroscopy (FCS) is a well-established analytical technique traditionally used to monitor molecular diffusion in dilute solutions, the dynamics of chemical reactions, and molecular processes inside living cells. In this review, we present the recent use of FCS for measuring the size of colloidal nanoparticles in solution. We review the theoretical basis and experimental implementation of this technique and its advantages and limitations. In particular, we show examples of the use of FCS to measure the size of gold nanoparticles, monitor the rotational dynamics of gold nanorods, and investigate the formation of protein coronas on nanoparticles. PMID:27215820

  17. 16 CFR 500.11 - Measurement of commodity length, how expressed.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., how expressed. Declaration of net quantity in terms of yards, feet, and inches shall be expressed as... terms of the largest whole unit (a yard or foot) with any remainder in terms of inches or common or decimal fractions of the foot or yard, except that it shall be optional to express the length in...

  18. 16 CFR 500.11 - Measurement of commodity length, how expressed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., how expressed. Declaration of net quantity in terms of yards, feet, and inches shall be expressed as... terms of the largest whole unit (a yard or foot) with any remainder in terms of inches or common or decimal fractions of the foot or yard, except that it shall be optional to express the length in...

  19. Prescribing Test Length for Criterion-Referenced Measurement. I. Posttests. ACT Technical Bulletin No. 18.

    ERIC Educational Resources Information Center

    Novick, Melvin R.; Lewis, Charles

    In a program of Individually Prescribed Instruction (IPI), where a student's progress through each level of a program of study is governed by his performance on a test dealing with individual behavioral objectives, there is considerable value in keeping the number of items on each test at a minimum. The specified test length for each objective…

  20. [A path-length correction method on biochemical parameter nondestructive measuring of folium].

    PubMed

    Zhang, Qian-Xuan; Zhang, Guang-Jun; Li, Qing-Bo

    2010-05-01

    Vis/NIR spectroscopy technology is capable of analyzing the content of biochemical parameter in folium rapidly and nondestructively. In the process of spectrum analysis, the variations in path-length between different samples exist, with the random light scattering and leaf thickness perturbations, which influence the precision of quantitative analysis model. In order to resolve this problem, an improved path-length correction method based on Extended Multiplicative Scattering Correction is presented. In this paper, firstly the theory of EMSC algorithm is deduced. EMSC method incorporates both chemical terms and wavelength functions to help realize the efficient separation of path-length and interest concentration. Secondly two experiments were implemented to demonstrate the validity of the method. In Experiment 1, sixteen samples of different thickness but almost the same chlorophyll content were selected, and how the path-length affects the spectrum was compared, after EMSC preprocessing, the variable coefficient of spectrum could approach the repeatability error of spectrometer. In Experiment 2, thirty-two samples of different thickness and chlorophyll content were selected. PLS model established using cross validation was employed to evaluate the efficiency of the presented algorithm. Before the preprocessing, the root mean squared error of prediction is 3.9 SPAD with 5 principal components. After preprocessing, the predicted root mean squared error is 2.2 SPAD with 12 principal components. The results indicate that the improved EMSC preprocessing method could exactly eliminate the spectrum difference caused by the path-length variations between different foliums, enhance the sensitivity of concentration and spectral data, and increase the precision of calibrated model. PMID:20672624

  1. Optomechanical correlations and signal self-amplification in interferometric measurements

    NASA Astrophysics Data System (ADS)

    Cohadon, P.-F.; Verlot, P.; Tavernarakis, A.; Briant, T.; Heidmann, A.

    2010-05-01

    Radiation pressure exerted by light in interferometric measurements is responsible for displacements of mirrors which appear as an additional back-action noise and limit the sensitivity of the measurement. We experimentally study these effects by monitoring in a very high-finesse optical cavity the displacements of a mirror with a sensitivity at the 10-20 m/ level. This very high sensitivity is a step towards the observation of fundamental quantum effects of radiation pressure such as the standard quantum limit in interferometric measurements. We report the observation of optomechanical correlations between two optical beams sent into the same moving mirror cavity. We also observed a self-amplification of a signal, which is a consequence of dynamical back-action of radiation pressure in a detuned cavity, and may improve the interferometric measurement sensitivity beyond the standard quantum limit.

  2. Correlated responses to long-term selection for clutch length in dwarf brown-egg layers carrying or not carrying the naked neck gene.

    PubMed

    Chen, C F; Tixier-Boichard, M

    2003-05-01

    Two dwarf brown-egg layer lines, differing in their genotype for the naked neck gene (NA), line L2 (NA*NA/*NA) and line L1 (NA*N/*N), have been selected for 16 generations for increased average clutch length. A control line from the same base population, dwarf and segregating for the NA gene, was maintained by random mating. Genetic parameters were estimated by a multivariate derivative-free restricted maximum likelihood procedure, and the NA gene effect was estimated within the unselected control line. The studied traits included clutch traits, egg production traits, abnormal eggs, egg weight at 36 wk, and BW at 42 wk. The average clutch length, egg number, and maximum clutch length were normalized using the Box-Cox transformation. In response to 16 generations of direct selection for increased average clutch length, other egg production traits, such as laying rate and total egg number, have been indirectly improved in a dwarf layer genetic background. The estimated heritabilities were 0.406 to 0.424 for transformed average clutch length (TCL), 0.373 to 0.411 for transformed egg number (TEN), 0.529 to 0.559 for age at first egg (AFE), 0.275 to 0.282 for laying rate (LR), 0.455 for dutch number (CN), and 0.319 for the number of double-yolked eggs (DYEN). The TCL had high genetic correlations with TEN (0.777), LR (0.863), maximum clutch length (0.902), and CN (-0.845). Selection for increased average clutch length was an effective method for increasing egg production. Line L2 showed a higher egg weight than L1, which indicates that the combined effect of NA and DW genes was favorable to maintain egg weight when egg number could be improved. Line L1 showed a higher number of DYEN, suggesting that the regulation of follicular maturation was changed in this line. PMID:12762391

  3. Sensor Selection for Estimation with Correlated Measurement Noise

    NASA Astrophysics Data System (ADS)

    Liu, Sijia; Chepuri, Sundeep Prabhakar; Fardad, Makan; Masazade, Engin; Leus, Geert; Varshney, Pramod K.

    2016-07-01

    In this paper, we consider the problem of sensor selection for parameter estimation with correlated measurement noise. We seek optimal sensor activations by formulating an optimization problem, in which the estimation error, given by the trace of the inverse of the Bayesian Fisher information matrix, is minimized subject to energy constraints. Fisher information has been widely used as an effective sensor selection criterion. However, existing information-based sensor selection methods are limited to the case of uncorrelated noise or weakly correlated noise due to the use of approximate metrics. By contrast, here we derive the closed form of the Fisher information matrix with respect to sensor selection variables that is valid for any arbitrary noise correlation regime, and develop both a convex relaxation approach and a greedy algorithm to find near-optimal solutions. We further extend our framework of sensor selection to solve the problem of sensor scheduling, where a greedy algorithm is proposed to determine non-myopic (multi-time step ahead) sensor schedules. Lastly, numerical results are provided to illustrate the effectiveness of our approach, and to reveal the effect of noise correlation on estimation performance.

  4. Measurements of Siple transmitter signals on the DE 1 satellite - Wave normal direction and antenna effective length

    NASA Technical Reports Server (NTRS)

    Sonwalker, V. S.; Inan, U. S.

    1986-01-01

    A new experimental technique is developed to simultaneously measure the wave propagation direction and the effective length of a small (L value much smaller than wavelength) electric dipole antenna on a spin-stabilized satellite in the magnetosphere. The technique relies on the near simultaneous measurement of single components of the electric and magnetic fields of a coherent VLF signal injected into the medium from a ground-based source. The spin fading characteristics of the signal received by the electric dipole and the magnetic loop antenna permit the measurement of the wave normal direction assuming whistler-mode propagation. In-situ and remote measurements of the local cold plasma density are used to determine the refractive index. The wave electric field is then inferred from the wave magnetic field as measured on the loop antenna, the refractive index and the direction of propagation. Comparing this electric field with the measured voltage across the dipole antenna leads to the determination of the effective length of the receiving electric dipole. The technique is applied to data from the Dynamics Explorer 1 satellite observations of whistler mode signals injected into the magnetosphere from the Siple, Antarctica, VLF transmitter. In one case, with the measured background cold plasma density being 15 el/cu cm, the effective length of the 200 m-long electric dipole antenna is found to be 222 + or - 56 m, i.e., about twice the conventional value.

  5. Measuring Fisher Information Accurately in Correlated Neural Populations

    PubMed Central

    Kohn, Adam; Pouget, Alexandre

    2015-01-01

    Neural responses are known to be variable. In order to understand how this neural variability constrains behavioral performance, we need to be able to measure the reliability with which a sensory stimulus is encoded in a given population. However, such measures are challenging for two reasons: First, they must take into account noise correlations which can have a large influence on reliability. Second, they need to be as efficient as possible, since the number of trials available in a set of neural recording is usually limited by experimental constraints. Traditionally, cross-validated decoding has been used as a reliability measure, but it only provides a lower bound on reliability and underestimates reliability substantially in small datasets. We show that, if the number of trials per condition is larger than the number of neurons, there is an alternative, direct estimate of reliability which consistently leads to smaller errors and is much faster to compute. The superior performance of the direct estimator is evident both for simulated data and for neuronal population recordings from macaque primary visual cortex. Furthermore we propose generalizations of the direct estimator which measure changes in stimulus encoding across conditions and the impact of correlations on encoding and decoding, typically denoted by Ishuffle and Idiag respectively. PMID:26030735

  6. Ternary Fission Studies by Correlation Measurements with Ternary Particles

    NASA Astrophysics Data System (ADS)

    Mutterer, Manfred

    2011-10-01

    The rare ternary fission process has been studied mainly by inclusive measurements of the energy distributions and fractional yields of the light charged particles (LCPs) from fission, or by experiments on the angular and energy correlation between LCPs and fission fragments (FFs). The present contribution presents a brief overview of more elaborate correlation measurements that comprise the emission of neutrons and γ rays with LCPs and FFs, or the coincident registration of two LCPs. These measurements have permitted identification of new modes of particle-accompanied fission, such as the population of excited states in LCPs, the formation of neutron-unstable nuclei as short-lived intermediate LCPs, as well as the sequential decay of particle-unstable LCPs and quaternary fission. Furthermore, the neutron multiplicity numbers bar ν (A) and distributions of fragment masses A, measured for the ternary fission modes with various LCP isotopes, give a valuable hint of the role played by nuclear shell structure in the fission process near scission. Finally, two different hitherto unknown asymmetries in ternary α-particle emission with respect to the fission axis, called the TRI and ROT effect, were studied in fission reactions induced by polarised cold neutrons.

  7. Attenuation length measurements of a liquid scintillator with LabVIEW and reliability evaluation of the device

    NASA Astrophysics Data System (ADS)

    Gao, Long; Yu, Bo-Xiang; Ding, Ya-Yun; Zhou, Li; Wen, Liang-Jian; Xie, Yu-Guang; Wang, Zhi-Gang; Cai, Xiao; Sun, Xi-Lei; Fang, Jian; Xue, Zhen; Zhang, Ai-Wu; Lü, Qi-Wen; Sun, Li-Jun; Ge, Yong-Shuai; Liu, Ying-Biao; Niu, Shun-Li; Hu, Tao; Cao, Jun; Lü, Jun-Guang

    2013-07-01

    An attenuation length measurement device was constructed using an oscilloscope and LabVIEW for signal acquisition and processing. The performance of the device has been tested in a variety of ways. The test results show that the set-up has a good stability and high precision (sigma/mean reached 0.4 percent). Besides, the accuracy of the measurement system will decrease by about 17 percent if a filter is used. The attenuation length of a gadolinium-loaded liquid scintillator (Gd-LS) was measured as 15.10±0.35 m where Gd-LS was heavily used in the Daya Bay Neutrino Experiment. In addition, one method based on the Beer-Lambert law was proposed to investigate the reliability of the measurement device, the R-square reached 0.9995. Moreover, three purification methods for Linear Alkyl Benzene (LAB) production were compared in the experiment.

  8. Measurements of 3D slip velocities and plasma column lengths of a gliding arc discharge

    SciTech Connect

    Zhu, Jiajian; Gao, Jinlong; Ehn, Andreas; Aldén, Marcus; Li, Zhongshan E-mail: alpers@ma.tum.de; Moseev, Dmitry; Kusano, Yukihiro; Salewski, Mirko; Alpers, Andreas E-mail: alpers@ma.tum.de; Gritzmann, Peter; Schwenk, Martin

    2015-01-26

    A non-thermal gliding arc discharge was generated at atmospheric pressure in an air flow. The dynamics of the plasma column and tracer particles were recorded using two synchronized high-speed cameras. Whereas the data analysis for such systems has previously been performed in 2D (analyzing the single camera image), we provide here a 3D data analysis that includes 3D reconstructions of the plasma column and 3D particle tracking velocimetry based on discrete tomography methods. The 3D analysis, in particular, the determination of the 3D slip velocity between the plasma column and the gas flow, gives more realistic insight into the convection cooling process. Additionally, with the determination of the 3D slip velocity and the 3D length of the plasma column, we give more accurate estimates for the drag force, the electric field strength, the power per unit length, and the radius of the conducting zone of the plasma column.

  9. Water Velocity Measurement on an Extended-Length Submerged Bar Screen at John Day Dam

    SciTech Connect

    Weiland, Mark A.; Escher, Charles

    2001-04-02

    This report describes a study of water velocity around an extended-length submerged bar screen (ESBS) at John Day Dam. The study was conducted for the U.S. Army Corps of Engineers by AScI Corporation and MEVATEC Corporation in March of 2000. This report was prepared by Pacific Northwest National Laboratory. ESBS are being studied as one method for diverting juvenile migrating fish from the dam's turbine intakes into the gate well and through the juvenile fish bypass channels.

  10. ABSOLUTE BUNCH LENGTH MEASUREMENTS AT THE ALS BY INCOHERENTSYNCHROTRON RADIATION FLUCTUATION ANALYSIS

    SciTech Connect

    Sannibale, Fernando; Zolotorev, Max S.; Filippetto, Daniele; Stupakov, Gennady V.

    2007-06-22

    By analysing the pulse to pulse intensity fluctuations ofthe radiation emitted by a charge particle in the incoherent part of thespectrum, it is possible to extract information about the spatialdistribution of the beam. At the Advanced Light Source (ALS) of theLawrence Berkeley National Laboratory, we have developed and tested asimple scheme based on this principle that allows for the absolutemeasurement of the bunch length. A description of the method and theexperimental results are presented.

  11. The Length Measurement in the Turkish Mathematics Curriculum: Its Potential to Contribute to Students' Learning

    ERIC Educational Resources Information Center

    Tan-Sisman, Gulcin; Aksu, Meral

    2012-01-01

    "Knowing and doing measurement" is a fundamental competency in real life since measuring attributes of objects in appropriate units and using measuring tools assist students to quantify and understand the world. For this reason, the study of measurement has a special place in every mathematics curriculum. Among the domains of measurement, length…

  12. Measurement of diffusion length and surface recombination velocity in Interdigitated Back Contact (IBC) and Front Surface Field (FSF) solar cells

    NASA Astrophysics Data System (ADS)

    Verlinden, Pierre; Van de Wiele, Fernand

    1985-03-01

    A method is proposed for measuring the diffusion length and surface recombination velocity of Interdigitated Back Contact (IBC) solar cells by means of a simple linear regression on experimental quantum efficiency values versus the inverse of the absorption coefficient. This method is extended to the case of Front Surface Field (FSF) solar cells. Under certain conditions, the real or the effective surface recombination velocity may be measured.

  13. Detecting correlated errors in state-preparation-and-measurement tomography

    NASA Astrophysics Data System (ADS)

    Jackson, Christopher; van Enk, S. J.

    2015-10-01

    Whereas in standard quantum-state tomography one estimates an unknown state by performing various measurements with known devices, and whereas in detector tomography one estimates the positive-operator-valued-measurement elements of a measurement device by subjecting to it various known states, we consider here the case of SPAM (state preparation and measurement) tomography where neither the states nor the measurement device are assumed known. For d -dimensional systems measured by d -outcome detectors, we find there are at most d2(d2-1 ) "gauge" parameters that can never be determined by any such experiment, irrespective of the number of unknown states and unknown devices. For the case d =2 we find gauge-invariant quantities that can be accessed directly experimentally and that can be used to detect and describe SPAM errors. In particular, we identify conditions whose violations detect the presence of correlations between SPAM errors. From the perspective of SPAM tomography, standard quantum-state tomography and detector tomography are protocols that fix the gauge parameters through the assumption that some set of fiducial measurements is known or that some set of fiducial states is known, respectively.

  14. Estimating correlation for a real-time measure of connectivity.

    PubMed

    Arunkumar, Akhil; Panday, Ashish; Joshi, Bharat; Ravindran, Arun; Zaveri, Hitten P

    2012-01-01

    There has recently been considerable interest in connectivity analysis of fMRI and scalp and intracranial EEG time-series. The computational requirements of the pair-wise correlation (PWC), the core time-series measure used to estimate connectivity, presents a challenge to the real-time estimation of the PWC between all pairs of multiple time-series. We describe a parallel algorithm for computing PWC in real-time for streaming data from multiple channels. The algorithm was implemented on the Intel Xeon™ and IBM Cell Broadband Engine™ platforms. We evaluated time to estimate correlation for signals recorded with different acquisition parameters as a comparison to real-time constraints. We demonstrate that the execution time of these efficient implementations meet real-time constraints in most instances. PMID:23367098

  15. Quantum dots thermal stability improves simultaneous phenotype-specific telomere length measurement by FISH-flow cytometry.

    PubMed

    Kapoor, Veena; Hakim, Fran T; Rehman, Najibah; Gress, Ronald E; Telford, William G

    2009-05-15

    Telomere length analysis has been greatly simplified by the quantitative flow cytometry technique FISH-flow. In this method, a fluorescein-labeled synthetic oligonucleotide complementary to the telomere terminal repeat sequence is hybridized to the telomere sequence and the resulting fluorescence measured by flow cytometry. This technique has supplanted the traditional laborious Southern blot telomere length measurement techniques in many laboratories, and allows single cell analysis of telomere length in high-throughput sample formats. Nevertheless, the harsh conditions required for telomere probe annealing (82 degrees C) has made it difficult to successfully combine this technique with simultaneous immunolabeling. Most traditional organic fluorescent probes (i.e. fluorescein, phycoerythrin, etc.) have limited thermal stability and do not survive the high temperature annealing process, despite efforts to covalently crosslink the antigen-antibody-fluorophore complex. This loss of probe fluorescence has made it difficult to measure FISH-flow in complex lymphocyte populations, and has generally forced investigators to use fluorescent-activated cell sorting to pre-separate their populations, a laborious technique that requires prohibitively large numbers of cells. In this study, we have substituted quantum dots (nanoparticles) for traditional fluorophores in FISH-flow. Quantum dots were demonstrated to possess much greater thermal stability than traditional low molecular weight and phycobiliprotein fluorophores. Quantum dot antibody conjugates directed against monocyte and T cell antigens were found to retain most of their fluorescence following the high temperature annealing step, allowing simultaneous fluorescent immunophenotyping and telomere length measurement. Since quantum dots have very narrow emission bandwidths, we were able to analyze multiple quantum dot antibody conjugates (Qdot 605, 655 and 705) simultaneously with FISH-flow measurement to assess the age

  16. Measuring capital market efficiency: Global and local correlations structure

    NASA Astrophysics Data System (ADS)

    Kristoufek, Ladislav; Vosvrda, Miloslav

    2013-01-01

    We introduce a new measure for capital market efficiency. The measure takes into consideration the correlation structure of the returns (long-term and short-term memory) and local herding behavior (fractal dimension). The efficiency measure is taken as a distance from an ideal efficient market situation. The proposed methodology is applied to a portfolio of 41 stock indices. We find that the Japanese NIKKEI is the most efficient market. From a geographical point of view, the more efficient markets are dominated by the European stock indices and the less efficient markets cover mainly Latin America, Asia and Oceania. The inefficiency is mainly driven by a local herding, i.e. a low fractal dimension.

  17. Correlation between seismic events and anomalous `VLF day-length' for west-east and east-west propagation paths

    NASA Astrophysics Data System (ADS)

    Ray, Suman; Chakrabarti, Sandip Kumar; Sasmal, Sudipta

    We present results of year-long analysis of VLF signals, both for VTX-Malda (`west-east' propagation path) and VTX-Pune (`east-west' propagation path). We analyzed whole year data of 2008 and 2009 for VTX-Malda and VTX-Pune propagation path, respectively. In both the cases we found that `VLF day-length' (defined as time difference between sunset terminator time and sunrise terminator time) became anomalously high 1-2 days before an earthquake. Besides this year-long study we have also done some case by case analysis. On 9th January, 2009 an earthquake of magnitude 5.5 occurred at Carlsberg Ridge (latitude 10.3(°) N, longitude 57.1(°) E). In a separate incident, on 3rd November, 2009, another earthquake of magnitude 5.4 occurred at Andaman Islands (latitude 14.1(°) N, longitude 93.1(°) E). We analyze VLF signals for VTX-Pune (`east-west’ propagation path) propagation path around these two earthquake days and found that for both of these cases, the `VLF-day-length' became anomalously high two days before the event. This agrees well with statistical analysis based on year-long data for VTX-Pune path. Furthermore, during time period of June, 2010, two major earthquakes of low-depth ( 10Km) and high magnitude (M>5) occurred near NWC-Salt Lake (east-west propagation path) propagation paths. First one occurred on 13th June, 2010 at Nicobar Islands, India (latitude 7.8(°) N, longitude 92.0(°) E). Its magnitude was 5.1 (in Richter scale). The second one of magnitude 6.0 (in Richter Scale) occurred on 19th June, 2010 at Andaman Islands, India (latitude 13.4(°) N, longitude 93.0(°) E). For both of these two earthquakes, we found that VLF-day-length, became anomalously high one day before earthquakes. We claim that these were pre-cursors of the earthquakes which occurred in Andaman and Nicober Islands.

  18. Protecting entanglement from correlated amplitude damping channel using weak measurement and quantum measurement reversal

    NASA Astrophysics Data System (ADS)

    Xiao, Xing; Yao, Yao; Xie, Ying-Mao; Wang, Xing-Hua; Li, Yan-Ling

    2016-06-01

    Based on the quantum technique of weak measurement, we propose a scheme to protect the entanglement from correlated amplitude damping decoherence. In contrast to the results of memoryless amplitude damping channel, we show that the memory effects play a significant role in the suppression of entanglement sudden death and protection of entanglement under severe decoherence. Moreover, we find that the initial entanglement could be drastically amplified by the combination of weak measurement and quantum measurement reversal even under the correlated amplitude damping channel. The underlying mechanism can be attributed to the probabilistic nature of weak measurements.

  19. Measurement of the imaginary part of the I = 1 N-barN S-wave scattering length

    SciTech Connect

    Mutchler, G.S.; Clement, J.; Kruk, J.; Moss, R.; Hungerford, E.; Kishimoto, T.; Mayes, B.; Pinsky, L.; Tang, L.; Xue, Y.; and others

    1988-08-01

    The survival time spectrum of slow antineutrons produced in a liquid-hydrogen target has been measured. From these data the imaginary part of the I = 1 spin-averaged S-wave antineutron proton scattering length has been deduced to be Ima/sub 1/ = -0.83 +- 0.07 fm. The result lies within the range of values calculated from current potential models. In addition, by combining a/sub 1/ with the antiproton-proton scattering length deduced from antiprotonic atoms, the imaginary part of the I = 0 spin-averaged N-barN scattering length was calculated to be Ima/sub 0/ = -1.07 +- 0.16 fm.

  20. Directional correlation measurements for gamma transitions in /sup 127/Te

    SciTech Connect

    de Souza, M.O.M.D.; Saxena, R.N.

    1985-02-01

    The directional correlation of coincident ..gamma.. transitions in /sup 127/Te has been measured following the ..beta../sup -/ decay of /sup 127/Sb (T/sub 1/2/ = 3.9 d) using Ge(Li)-Ge(Li) and Ge(Li)-NaI(T1) gamma spectrometers. Measurements have been carried out for 14 gamma cascades resulting in the determination of multipole mixing ratios delta(E2/M1) for 15 ..gamma.. transitions. The present results permitted a definite spin assignment of (7/2) for the 785 keV level and confirmation of several previous assignments to other levels in /sup 127/Te. The g factor of the 340 keV ((9/2)/sup -/) level has also been measured using the integral perturbed angular correlation method in the hyperfine magnetic field of a Te in Ni matrix. The results of the g factor as well as the mixing ratio for the 252 keV ((9/2)/sup -/..-->..(11/2)/sup -/) transition support the earlier interpretation of this state as an anomalous coupling state.

  1. Correlation of pressure measurements with angiographic characteristics predisposing to hemorrhage and steal in cerebral arteriovenous malformations

    SciTech Connect

    Norbash, A.M.; Marks, M.P.; Lane, B.

    1994-05-01

    To determine whether there is a physiologic explanation for the predisposition of patients with certain angiographic characteristics to symptoms of hemorrhage and steal. Superselective transcatheter feeding arterial pressure and mean arterial pressure measurements were obtained before embolotherapy in 32 patients with cerebral arteriovenous malformations. Pressures were correlated with previously described angioarchitectural characteristics predisposing to hemorrhage and steal. These included size of the arteriovenous malformation, feeding artery length, venous drainage pattern, and angiomatous change. The feeding arterial pressure and feeding arterial pressure/mean arterial pressure ratios were significantly decreased in patients with angiomatous change. Feeding arterial pressure and feeding arterial pressure/mean arterial pressure ratios progressively decreased as lesions went from peripheral, to mixed, to central venous drainage. A trend for lower feeding arterial pressure was also demonstrated with greater feeding pedicle length. A statistically significant correlation could not be demonstrated between feeding arterial pressure or feeding arterial pressure/mean arterial pressure ratios and size of the arteriovenous malformation, hemorrhage, or symptoms of steal. Feeding arterial pressure measurements help provide a physiologic basis for the relationship between certain angiographic characteristics and hemorrhage and steal symptoms in patients with arteriovenous malformation. 27 refs., 1 fig.

  2. Efficient measurement of point-to-set correlations and overlap fluctuations in glass-forming liquids

    NASA Astrophysics Data System (ADS)

    Berthier, Ludovic; Charbonneau, Patrick; Yaida, Sho

    2016-01-01

    Cavity point-to-set correlations are real-space tools to detect the roughening of the free-energy landscape that accompanies the dynamical slowdown of glass-forming liquids. Measuring these correlations in model glass formers remains, however, a major computational challenge. Here, we develop a general parallel-tempering method that provides orders-of-magnitude improvement for sampling and equilibrating configurations within cavities. We apply this improved scheme to the canonical Kob-Andersen binary Lennard-Jones model for temperatures down to the mode-coupling theory crossover. Most significant improvements are noted for small cavities, which have thus far been the most difficult to study. This methodological advance also enables us to study a broader range of physical observables associated with thermodynamic fluctuations. We measure the probability distribution of overlap fluctuations in cavities, which displays a non-trivial temperature evolution. The corresponding overlap susceptibility is found to provide a robust quantitative estimate of the point-to-set length scale requiring no fitting. By resolving spatial fluctuations of the overlap in the cavity, we also obtain quantitative information about the geometry of overlap fluctuations. We can thus examine in detail how the penetration length as well as its fluctuations evolve with temperature and cavity size.

  3. The ground state structures of disilane, methyl silane and the silyl halides, and an SiH bond length correlation with stretching frequency

    NASA Astrophysics Data System (ADS)

    Duncan, J. L.; Harvie, J. L.; McKean, D. C.; Cradock, S.

    1986-07-01

    Infrared spectra of the molecules Si 2HD 5, SiHD 2CH 3, SiH 3CHD 2, SiHD 2X (X = F, Cl, Br, I) have been recorded at 0.05 cm -1 resolution. Analyses of "perpendicular" fundamentals of these very slightly asymmetric top molecules permit the accurate determination of their ground state ( A0— B0) constants, from which the A 0 rotational constants may be obtained. When combined with all known Raman and microwave constants, this enables the ground state structures to be determined with precision, allowance being made for the shortening of SiH(CH) bonds on deuteration. For disilane this work represents the first spectroscopic determination of a complete structure, while for the silyl halides it demonstrates overestimates in the SiH bond length of nearly 1% by previous workers. In the case of methyl silane, comparison with a recent ab initio structure calculation reveals a considerable overestimate of the CSi bond length in the latter. A correlation between isolated SiH stretching frequency and ground state bond length over 15 molecules reveals a somewhat reduced sensitivity compared with the corresponding CH correlation. Nevertheless, a predictive capability of better than ±0.003 Å seems possible from the isolated SiH stretching frequency, at least for molecules with fully saturated bonding.

  4. Atmospheric lateral and longitudinal turbulent length scales (measured at 600 to 800 meters above grade level)

    NASA Technical Reports Server (NTRS)

    Cliff, W. C.; Skarda, J. R.

    1987-01-01

    NASA's Airborne Doppler Lidar System has been used to obtain a detailed 'instantaneous' mapping of horizontal spatial wind fields at 600-800 m elevations on the east side of the San Gorgonio Pass in California, in the form of checkerboard-fashion horizontal wind vectors spaced at 300 m intervals along and normal to the flight path. Spatial autocorrelations for the lateral and longitudinal components are ensemble-averaged, and integral turbulent length scales are computed for the wind fields' longitudinal and lateral directions. The flow in the region studied does not appear to be isotropic.

  5. Determination of Axial Length Requiring Adjustment of Measured Circumpapillary Retinal Nerve Fiber Layer Thickness for Ocular Magnification

    PubMed Central

    Hirasawa, Kazunori; Shoji, Nobuyuki; Yoshii, Yukako; Haraguchi, Shota

    2014-01-01

    Purpose To determine the axial length requiring adjustment of measured circumpapillary retinal nerve fiber layer (cpRNFL) thickness to account for ocular magnification during spectral-domain optical coherence tomography (SD-OCT). Methods In this prospective study, 148 eyes of 148 healthy student volunteers were imaged by two examiners using three-dimensional SD-OCT. In 54 randomly selected eyes, total cpRNFL thickness was measured with and without adjustment for ocular magnification to establish intra-examiner and inter-examiner measurement error. The 148 eyes were then divided into three groups according to the error values: control group (difference in the corrected and uncorrected total cpRNFL thickness was within the measurement error range), thinner group (the corrected total cpRNFL thickness was less than the uncorrected one), and thicker group (the corrected total cpRNFL thickness was more than the uncorrected one). The cutoff values of axial length between the control and the other groups were calculated by receiver operating characteristic analysis. Results Measurement error ranged from 4.2 to 5.3 µm; the threshold value was defined as 5.3 µm. The cutoff values of axial length between the thinner and the control groups and between the control and the thicker groups were 23.60 (area under the curve [AUC] = 0.959) and 25.55 (AUC = 0.944) mm, respectively. Conclusions Axial lengths shorter than 23.60 mm and longer than 25.55 mm require adjustment of measured cpRNFL thickness to account for ocular magnification during SD-OCT. Clinical Trial Registration UMIN Clinical Trials Registry (http://www.umin.ac.jp/) under unique trial number UMIN000013248 (date of registration: 02/24/2014) PMID:25215521

  6. Measurement of laminar burning speeds and Markstein lengths using a novel methodology

    SciTech Connect

    Tahtouh, Toni; Halter, Fabien; Mounaim-Rousselle, Christine

    2009-09-15

    Three different methodologies used for the extraction of laminar information are compared and discussed. Starting from an asymptotic analysis assuming a linear relation between the propagation speed and the stretch acting on the flame front, temporal radius evolutions of spherically expanding laminar flames are postprocessed to obtain laminar burning velocities and Markstein lengths. The first methodology fits the temporal radius evolution with a polynomial function, while the new methodology proposed uses the exact solution of the linear relation linking the flame speed and the stretch as a fit. The last methodology consists in an analytical resolution of the problem. To test the different methodologies, experiments were carried out in a stainless steel combustion chamber with methane/air mixtures at atmospheric pressure and ambient temperature. The equivalence ratio was varied from 0.55 to 1.3. The classical shadowgraph technique was used to detect the reaction zone. The new methodology has proven to be the most robust and provides the most accurate results, while the polynomial methodology induces some errors due to the differentiation process. As original radii are used in the analytical methodology, it is more affected by the experimental radius determination. Finally, laminar burning velocity and Markstein length values determined with the new methodology are compared with results reported in the literature. (author)

  7. A volumetric approach to path-length measurements is essential when treating radiotherapy with modulated beams

    SciTech Connect

    Forde, Elizabeth; Booth, Jeremy; Leech, Michelle

    2014-07-01

    The established dosimetric benefits of intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy have lead to their increased use in prostate radiotherapy. Complimenting these techniques, volumetric image guidance has supported increased positional accuracy. In addition, 3-dimensional image guidance has also allowed for assessment of potential dosimetric variation that can be attributed to a deformation of either internal or external structures, such as rectal distension or body contour. Compounding these issues is the variation of tissue density through which the new field position passes and also the variation of dose across a modulated beam. Despite the growing level of interest in this area, there are only a limited number of articles that examine the effect of a variation in beam path length, particularly across a modulated field. IMRT and volumetric-modulated radiation therapy (VMAT) fields are dynamic in nature, and the dose gradient within these fields is variable. Assessment of variation of path length away from the beam's central axis and across the entire field is vital where there is considerable variation of dose within the field, such as IMRT and VMAT. In these cases, reliance on the traditional central axis to focus skin distances is no longer appropriate. This article discusses these more subtle challenges that may have a significant clinical effect if left unrecognized and undervalued.

  8. Measuring a Kaluza-Klein radius smaller than the Planck length

    NASA Astrophysics Data System (ADS)

    Reifler, Frank; Morris, Randall

    2003-03-01

    Hestenes has shown that a bispinor field on a Minkowski space-time is equivalent to an orthonormal tetrad of one-forms together with a complex scalar field. More recently, the Dirac and Einstein equations were unified in a tetrad formulation of a Kaluza-Klein model which gives precisely the usual Dirac-Einstein Lagrangian. In this model, Dirac’s bispinor equation is obtained in the limit for which the radius of higher compact dimensions of the Kaluza-Klein manifold becomes vanishingly small compared with the Planck length. For a small but finite radius, the Kaluza-Klein model predicts the velocity splitting of single fermion wave packets. That is, the model predicts that a single fermion wave packet will split into two wave packets with slightly different group velocities. The observation of such wave packet splits would determine the size of the Kaluza-Klein radius. If wave packet splits were not observed in experiments with currently achievable accuracies, the Kaluza-Klein radius would be bounded by at most 10-25 times the Planck length.

  9. Lateral acetabular labral length is inversely related to acetabular coverage as measured by lateral center edge angle of Wiberg.

    PubMed

    Petersen, Brian D; Wolf, Bryan; Lambert, Jeffrey R; Clayton, Carolyn W; Glueck, Deborah H; Jesse, Mary Kristen; Mei-Dan, Omer

    2016-08-01

    Patients with developmental dysplasia of the hip often have compensatory labral hypertrophy, which presumably lends stability to an unstable joint. Conversely, patients with acetabular overcoverage may have small or ossified labra. The purpose of this study is to explore the interaction of labral length with the degree of acetabular hip coverage. A retrospective cohort of patients with hip pain presenting to a hip preservation center, who had undergone hip magnetic resonance imaging and AP pelvis radiographs were studied. General linear multivariate models were used to assess the association between three measures of labral length (lateral, anterior and anterior inferior locations along the acetabular rim) and the X-ray derived lateral center edge angle (LCEA) of Wiberg. Of the three acetabular labral locations measured, only the lateral labrum was associated with LCEA Wiberg (P = 0.0008). Lateral labral length increases as LCEA of Wiberg decreases. The anterior and anterior inferior labral locations did not show a predictable increase in labral length as LCEA Wiberg decreased. PMID:27583157

  10. Lateral acetabular labral length is inversely related to acetabular coverage as measured by lateral center edge angle of Wiberg

    PubMed Central

    Petersen, Brian D.; Wolf, Bryan; Lambert, Jeffrey R.; Clayton, Carolyn W.; Glueck, Deborah H.; Jesse, Mary Kristen; Mei-Dan, Omer

    2016-01-01

    Patients with developmental dysplasia of the hip often have compensatory labral hypertrophy, which presumably lends stability to an unstable joint. Conversely, patients with acetabular overcoverage may have small or ossified labra. The purpose of this study is to explore the interaction of labral length with the degree of acetabular hip coverage. A retrospective cohort of patients with hip pain presenting to a hip preservation center, who had undergone hip magnetic resonance imaging and AP pelvis radiographs were studied. General linear multivariate models were used to assess the association between three measures of labral length (lateral, anterior and anterior inferior locations along the acetabular rim) and the X-ray derived lateral center edge angle (LCEA) of Wiberg. Of the three acetabular labral locations measured, only the lateral labrum was associated with LCEA Wiberg (P = 0.0008). Lateral labral length increases as LCEA of Wiberg decreases. The anterior and anterior inferior labral locations did not show a predictable increase in labral length as LCEA Wiberg decreased. PMID:27583157

  11. The Effect of Error Correlation on Interfactor Correlation in Psychometric Measurement

    ERIC Educational Resources Information Center

    Westfall, Peter H.; Henning, Kevin S. S.; Howell, Roy D.

    2012-01-01

    This article shows how interfactor correlation is affected by error correlations. Theoretical and practical justifications for error correlations are given, and a new equivalence class of models is presented to explain the relationship between interfactor correlation and error correlations. The class allows simple, parsimonious modeling of error…

  12. Measures of correlations in infinite-dimensional quantum systems

    NASA Astrophysics Data System (ADS)

    Shirokov, M. E.

    2016-05-01

    Several important measures of correlations of the state of a finite-dimensional composite quantum system are defined as linear combinations of marginal entropies of this state. This paper is devoted to infinite-dimensional generalizations of such quantities and to an analysis of their properties. We introduce the notion of faithful extension of a linear combination of marginal entropies and consider several concrete examples, the simplest of which are quantum mutual information and quantum conditional entropy. Then we show that quantum conditional mutual information can be defined uniquely as a lower semicontinuous function on the set of all states of a tripartite infinite-dimensional system possessing all the basic properties valid in finite dimensions. Infinite-dimensional generalizations of some other measures of correlations in multipartite quantum systems are also considered. Applications of the results to the theory of infinite-dimensional quantum channels and their capacities are considered. The existence of a Fawzi-Renner recovery channel reproducing marginal states for all tripartite states (including states with infinite marginal entropies) is shown. Bibliography: 47 titles.

  13. Correlation spectrum analyzer for direct measurement of device current noise

    NASA Astrophysics Data System (ADS)

    Ferrari, Giorgio; Sampietro, Marco

    2002-07-01

    This article analyzes the realization and the performance of a correlation spectrum analyzer specifically conceived to directly measure the current noise produced by electronic devices with maximum sensitivity. The text describes in detail and gives the design rules of the instrument input amplifiers taking into consideration noise, dynamic range, stability, and bandwidth, together with the effects that a device under test (DUT) having complex impedance introduce. This article shows that the proposed scheme may allow current noise measurements with a sensitivity improved by few orders of magnitude with respect to a standard spectrum analyzer and to a correlation analyzer in voltage scheme whenever the DUT has an impedance larger than few 10 kOmega. Such a sensitivity makes the proposed instrument ideal for the characterization of advanced devices, such as ultrashort channel metal-oxide-semiconductor field effect transistors, mesoscopic junctions, or spin dependent electron transfer devices where it may be necessary to detect noise levels as low as fA/RADICAL:[[RADICAND:[Hz

  14. Correlations of Clinical and Laboratory Measures of Balance in Older Men and Women: The MOBILIZE Boston Study

    PubMed Central

    Nguyen, Uyen-Sa D.T.; Kiel, Douglas P.; Li, Wenjun; Galica, Andrew M.; Kang, Hyun Gu; Casey, Virginia A.; Hannan, Marian T.

    2012-01-01

    Objective Impaired balance is associated with falls in older adults. However, there is no accepted gold standard on how balance should be measured. Few studies have examined measures of postural sway and clinical balance concurrently in large samples of community-dwelling older adults. We examined the associations among four types of measures of laboratory- and clinic-based balance in a large population-based cohort of older adults. Methods We evaluated balance measures in the MOBILIZE Boston Study (276 men, 489 women, 64–97 years). Measures included: (1) laboratory-based anteroposterior (AP) path length and average sway speed, mediolateral (ML) average sway and root-mean-square, and area of ellipse postural sway; (2) Short Physical Performance Battery (SPPB); (3) Berg Balance Scale; and (4) one-leg stand. Spearman Rank Correlation Coefficients (r) were assessed among the balance measures. Results Area of ellipse sway was highly correlated with the ML sway measures (r >0.9, p < 0.0001), and sway speed was highly correlated with AP sway (r=0.97, p < 0.0001). The Berg Balance Scale was highly correlated with SPPB (r=0.7, p<0.001), and one-leg stand (r=0.8, p<0.001). Correlations between the laboratory- and clinic-based balance measures were low but statistically significant (0.2 < r < 0.3, p<0.0001). Conclusion Clinic-based balance measures, and laboratory-based measures comparing area of ellipse with ML sways or sway speed with AP sway, are highly correlated. Clinic- with laboratory-based measures are less correlated. As both laboratory- and clinic-based measures inform balance in older adults but are not highly correlated with each other, future work should investigate the differences. PMID:22745045

  15. Measurements of the Conduction-Zone Length and Mass Ablation Rate in Cryogenic Direct-Drive Implosions on OMEGA

    NASA Astrophysics Data System (ADS)

    Michel, D. T.; Davis, A. K.; Goncharov, V. N.; Sangster, T. C.; Hu, S. X.; Igumenshchev, I. V.; Meyerhofer, D. D.; Seka, W.; Froula, D. H.

    2015-04-01

    Measurements of the conduction-zone length (110 ±20 μ m at t =2.8 ns ), the averaged mass ablation rate of the deuterated plastic (7.95 ±0.3 μ g /ns ), shell trajectory, and laser absorption are made in direct-drive cryogenic implosions and are used to quantify the electron thermal transport through the conduction zone. Hydrodynamic simulations that use nonlocal thermal transport and cross-beam energy transfer models reproduce these experimental observables. Hydrodynamic simulations that use a time-dependent flux-limited model reproduce the measured shell trajectory and the laser absorption but underestimate the mass ablation rate by ˜10 % and the length of the conduction zone by nearly a factor of 2.

  16. Method and apparatus for measuring minority carrier lifetimes and bulk diffusion length in P-N junction solar cells

    NASA Technical Reports Server (NTRS)

    Vonroos, O. H. (Inventor)

    1978-01-01

    Carrier lifetimes and bulk diffusion length are qualitatively measured as a means for qualification of a P-N junction photovoltaic solar cell. High frequency (blue) monochromatic light pulses and low-frequency (red) monochromatic light pulses were alternately applied to the cell while it was irradiated by light from a solar simulator, and synchronously displaying the derivative of the output voltage of the cell on an oscilloscope. The output voltage is a measure of the lifetimes of the minority carriers (holes) in the diffused N layer and majority carriers (electrons) in the bulk P material, and of the diffusion length of the bulk silicon. By connecting a reference cell in this manner with a test cell to be tested in reverse parallel, the display of a test cell that matches the reference cell will be a substantially zero output.

  17. Direct and precise length measurement of single, stretched DNA fragments by dynamic molecular combing and STED nanoscopy.

    PubMed

    Kim, Namdoo; Kim, Hyung Jun; Kim, Younggyu; Min, Kyung Suk; Kim, Seong Keun

    2016-09-01

    A combination of DNA stretching method and super-resolution nanoscopy allows an accurate and precise measurement of the length of DNA fragments ranging widely in size from 117 to 23,130 bp. BstEII- and HindIII-treated λDNA fragments were stained with an intercalating dye and then linearly stretched on a coverslip by dynamic molecular combing. The image of individual DNA fragments was obtained by stimulated emission depletion nanoscopy. For DNA fragments longer than ∼1000 bp, the measured lengths of DNA fragments were consistently within ∼0.5 to 1.0 % of the reference values, raising the possibility of this method in a wide range of applications including facile detection for copy number variations and trinucleotide repeat disorder. PMID:27457103

  18. Measurements of the conduction-zone length and mass ablation rate in cryogenic direct-drive implosions on OMEGA

    SciTech Connect

    Michel, D. T.; Davis, A. K.; Goncharov, V. N.; Sangster, T. C.; Hu, S. X.; Igumenshchev, I. V.; Meyerhofer, D. D.; Seka, W.; Froula, D. H.

    2015-04-14

    Measurements of the conduction-zone length (110 ± 20 μm at t = 2.8 ns), the averaged mass ablation rate of the deuterated plastic (7.95 ± 0.3 μg/ns), shell trajectory, and laser absorption are made in direct-drive cryogenic implosions and are used to quantify the electron thermal transport through the conduction zone. Hydrodynamic simulations that use nonlocal thermal transport and cross-beam energy transfer models reproduce these experimental observables. Hydrodynamic simulations that use a time-dependent flux-limited model reproduce the measured shell trajectory and the laser absorption but underestimate the mass ablation rate by ~10% and the length of the conduction zone by nearly a factor of 2.

  19. Recent results and prospects for correlation ECE measurements on TCV

    NASA Astrophysics Data System (ADS)

    Porte, L.; Coda, S.; Goodman, T. P.; Pochelon, A.; Udintsev, V. S.; Vuille, V.

    2012-09-01

    The Tokamak a Configuration Variable (TCV) has a two channel correlation electron cyclotron emission (CECE) radiometer with a line of sight perpendicular to the magnetic field. The antenna pattern of this radiometer limits resolution to kθ < 112 m-1 or kθρs < 0.3 at 500 kHz. It can access the region with minor radius ρvol < 0.7. A series of measurements has been made of the turbulence spectra at positive and negative triangularity and as a function of collisionality. Also, a series of measurements has been made as a function of poloidal angle, by varying the plasma vertical position with respect to the antenna, the measurements being made on the same flux surface. It is planned to extensively upgrade the diagnostic by integrating four more channels and acquiring a new front-end for the radiometer. This upgrade should reduce the required number of shots for a radial scan by a factor four and improve the signal-to-noise ratio. It is also planned to use a high gain antenna that will extend access to kρ < 174m-1 or kθρs < 0.5 at 500 kHz. The present system, measurements and the upgrade are described in this paper.

  20. Northern San Andreas Earthquake Recurrence: Rupture lengths, Correlations and Constrained OxCal Analysis of Event Ages

    NASA Astrophysics Data System (ADS)

    Morey, A. E.; Goldfinger, C.; Erhardt, M.; Nelson, C. H.; Johnson, J. E.; Gutierrez-Pastor, J.

    2005-12-01

    We are using multiple proxies, including XRF analysis, to determine hemipelagic thickness between turbidite events recorded in cores along the offshore northern San Andreas margin. Inter-event times are calculated from these improved estimates of sediment thickness and regression-determined sedimentation rates, and used along with known stratigraphic information to constrain calibrated radiocarbon age ranges using Bayesian statistical methods within the program OxCal. OxCal can also be used to combine multiple ages for the same event. Multiple ages are given "credit" where age ranges overlap, resulting in reduced 1- or 2-sigma age ranges compared to averaging peak ages and propagating errors. These methods reduce calendar age variability of events along strike that are thought to correlate. We tested three methods of estimating calendar ages, using the most recent events in a Noyo Canyon core. These methods are: 1. unconstrained radiocarbon age calibration, 2. age determination using known dates and inter-event time calculated from hemipelagic thickness and the regression-determined sedimentation rate, and 3. (preferred method) use OxCal's sequence option to calibrate and constrain radiocarbon ages given all available stratigraphic information, including date of collection, historical or geological datums, inter-event times and radiocarbon ages. The upper-most event was chosen for these tests because it is known to be the 1906 earthquake and the 20th century reservoir correction is well known in this area. The penultimate event was chosen because it has been dated at multiple land sites. 1906 event: Unconstrained calibration: calibration of the radiocarbon age of the 1906 event yields an age of ~1913, (1σ: 1898-1940). Sedimentation time: subtracting the time represented by the hemipelagic thickness above the 1906 event from the date of collection (1999) yields an age of ~1904. OxCal sequence: constrained calibration yields an age of ~1902 (1σ: 1880

  1. Experimental evaluation of nonclassical correlations between measurement outcomes and target observable in a quantum measurement

    NASA Astrophysics Data System (ADS)

    Iinuma, Masataka; Suzuki, Yutaro; Nii, Taiki; Kinoshita, Ryuji; Hofmann, Holger F.

    2016-03-01

    In general, it is difficult to evaluate measurement errors when the initial and final conditions of the measurement make it impossible to identify the correct value of the target observable. Ozawa proposed a solution based on the operator algebra of observables which has recently been used in experiments investigating the error-disturbance trade-off of quantum measurements. Importantly, this solution makes surprisingly detailed statements about the relations between measurement outcomes and the unknown target observable. In the present paper, we investigate this relation by performing a sequence of two measurements on the polarization of a photon, so that the first measurement commutes with the target observable and the second measurement is sensitive to a complementary observable. While the initial measurement can be evaluated using classical statistics, the second measurement introduces the effects of quantum correlations between the noncommuting physical properties. By varying the resolution of the initial measurement, we can change the relative contribution of the nonclassical correlations and identify their role in the evaluation of the quantum measurement. It is shown that the most striking deviation from classical expectations is obtained at the transition between weak and strong measurements, where the competition between different statistical effects results in measurement values well outside the range of possible eigenvalues.

  2. Quantifying Path Length: Fourth-Grade Children's Developing Abstractions for Linear Measurement

    ERIC Educational Resources Information Center

    Barrett, Jeffrey E.; Clements, Douglas H.

    2003-01-01

    This article describes how children build increasingly abstract knowledge of linear measurement, emphasizing ways they relate space and number. Assessments indicate children struggle to understand measurement, especially concepts related to complex paths as in perimeter tasks. This article draws on developmental accounts of children's knowledge of…

  3. Outdoor radon concentration measurements: some correlation with major urban pollutants.

    PubMed

    Garbero, V; Dellacasa, G; Bianchi, D; Magnoni, M; Erbetta, L

    2009-12-01

    Air pollutants concentration in the urban air strongly depends on the properties of the planetary boundary layer (the lower region of the atmosphere), roughly up to 1 km from Earth's surface. Radioactive radon gas has been recognised by various authors as a valuable natural tracer of transport and dispersion within this layer. To achieve a better comprehension of the urban pollution dynamic in the town of Alessandria, situated in the Po Valley in the north-west of Italy, a system for continuous measurement of radon concentration in outdoor air was experimented. This paper presents the first results obtained: the hourly trend of radon concentration in the diurnal course during different seasons and its correlation with the concentration of the major urban pollutants. PMID:19906661

  4. Expression of human protection of telomere 1 correlates with telomere length and radiosensitivity in the human laryngeal cancer Hep-2 cell line

    PubMed Central

    LEI, HAN; FENG, DALI; ZHOU, FUXIANG; XU, HUI; TANG, TIAN; YU, HAIJUN; XIE, CONGHUA; ZHOU, YUNFENG

    2015-01-01

    The close association between telomere length and radiosensitivity has been established by several studies. There is also a hypothesis that telomere length may be regulated by human protection of telomere 1 (hPOT1) in human carcinoma cells. In the present study, the hPOT1 level between the radioresistant Hep-2R cells and the wild-type were compared, and the results showed that the hPOT1 gene was upregulated in the radioresistant Hep-2R cell lines compared with the wild-type. This suggested that the expression level of hPOT1 correlates with radiosensitivity. Additionally, an hPOT1-directed short hairpin (sh)RNA plasmid was constructed and transferred into the Hep-2R cells, which lead to telomere shortening, an increase in apoptosis and markedly decreased growth of the RNAi-Hep-2R cell line. These results demonstrate that hPOT1-directed shRNAs are associated with telomere length and radiosensitivity, and maybe a potent sensitizer for laryngeal cancer radiotherapy. PMID:26622642

  5. Measurement and model prediction of proton-recoil track length distributions in NTA film dosimeters for neutron energy spectroscopy and retrospective dose assessment

    NASA Astrophysics Data System (ADS)

    Taulbee, Timothy D.

    The goal of this research was to determine whether neutron dose reconstruction could be improved through re-analysis of historic NTA films worn by workers in the 1950 through the 1970s. To improve neutron dose reconstruction, the underlying neutron energy spectra is critical in determining the organ dose due to energy dependence of the dose conversion factor as well as the application of radiation weighting factors used in epidemiology and probability of causation calculations. Monte Carlo models of proton-recoil track length distributions were developed and benchmarked against measurement data for both NTA and Ilford films. These models, when applied to several NTA film dosimeter configurations, demonstrated that proton-recoil track length distributions change based upon incident neutron energy. The neutron energy spectra changes that result from the general work environment such as source term and shielding can subsequently be modeled to predict the response of the NTA film dosimeter. An Automatic NTA Film Analyzer has been designed and developed to determine if the difference in proton-recoil track length distributions predicted by the Monte Carlo models could be measured and whether these differences could be correlated to the incident neutron energy spectra. The design required the development of a 2D-3D hybrid track recognition algorithm for a three dimensional analysis of the NTA film in order to accurately determine the proton-recoil track length for subsequent neutron energy determination. NTA films exposed to a plutonium fluoride (PuF4) and polonium boron (PoB) calibration sources were measured and compared. The proton-recoil track lengths were used to reconstruct the incident neutron energy spectra demonstrating the functionality of the analyzer and that reconstruction of the neutron energy spectra from NTA films is feasible. These measurements were compared to the Monte Carlo models and confirmed the applicability of using models to determine the NTA

  6. Measurement of the minority carrier diffusion length and edge surface-recombination velocity in InP

    NASA Technical Reports Server (NTRS)

    Bailey, Sheila G.; Hakimzadeh, Roshanak

    1993-01-01

    A scanning electron microscope (SEM) was used to measure the electron (minority carrier) diffusion length (L(sub n)) and the edge surface-recombination velocity (V(sub s)) in zinc-doped Czochralski-grown InP wafers. Electron-beam-induced current (EBIC) profiles were obtained in specimens containing a Schottky barrier perpendicular to the scanned (edge) surface. An independent technique was used to measure V(sub s), and these values were used in a theoretical expression for normalized EBIC. A fit of the experimental data with this expression enabled us to determine L(sub n).

  7. The receptor binding affinity of monocyclic [Ala3,Xaa11]endothelin-1 analogs correlates with inducible helix length.

    PubMed

    Andersen, N H; Harris, S M; Lee, V G; Liu, E C; Moreland, S; Hunt, J T

    1995-02-01

    required side chains optimally for interaction with the ETA receptor. For the 1,15-monocyclic analogs differing only at position 11, ETA binding affinity and vasoconstrictor potency correlate with the facility which a 7-8 residue long helix can be induced. This presumably includes the segment Glu10-->Cys15 in all cases and may represent the full sequence from Lys9-->His16. CD studies also reveal that the C-terminal fragment of endothelins is not a fully disordered 'random coil' either alone or attached to the endothelin core. PMID:7796045

  8. Calculation of Evolutionary Correlation between Individual Genes and Full-Length Genome: A Method Useful for Choosing Phylogenetic Markers for Molecular Epidemiology

    PubMed Central

    Wang, Shuai; Luo, Xuenong; Wei, Wei; Zheng, Yadong; Dou, Yongxi; Cai, Xuepeng

    2013-01-01

    Individual genes or regions are still commonly used to estimate the phylogenetic relationships among viral isolates. The genomic regions that can faithfully provide assessments consistent with those predicted with full-length genome sequences would be preferable to serve as good candidates of the phylogenetic markers for molecular epidemiological studies of many viruses. Here we employed a statistical method to evaluate the evolutionary relationships between individual viral genes and full-length genomes without tree construction as a way to determine which gene can match the genome well in phylogenetic analyses. This method was performed by calculation of linear correlations between the genetic distance matrices of aligned individual gene sequences and aligned genome sequences. We applied this method to the phylogenetic analyses of porcine circovirus 2 (PCV2), measles virus (MV), hepatitis E virus (HEV) and Japanese encephalitis virus (JEV). Phylogenetic trees were constructed for comparisons and the possible factors affecting the method accuracy were also discussed in the calculations. The results revealed that this method could produce results consistent with those of previous studies about the proper consensus sequences that could be successfully used as phylogenetic markers. And our results also suggested that these evolutionary correlations could provide useful information for identifying genes that could be used effectively to infer the genetic relationships. PMID:24312527

  9. The formation of interstellar molecular lines in a turbulent velocity field with finite correlation length. II - The case sigma much greater than v(therm)

    NASA Astrophysics Data System (ADS)

    Kegel, W. H.; Piehler, G.; Albrecht, M. A.

    1993-03-01

    We investigated the formation of interstellar molecular lines in a turbulent velocity field with finite correlation length, extending previous work (Albrecht and Kegel, 1987) to the regime sigma much greater than V(therm). For this we transformed the generalized transfer equation by introducing a new, Delta(nu)-dependent velocity coordinate the origin of which corresponds to the center of the profile of the absorption coefficient. This transformation allows in the case of sigma much greater than V(therm) to reduce the numerical effort considerably. We give numerical results for NLTE-calculations for a 10-level CO molecule for (sigma/v(therm)) = 20 as well as for comparison for sigma = v(therm). Our results show that a finite correlation length affects strongly the line profiles, the line width, and the intensity ratios. At low densities also the excitation conditions are effected, i.e., the NLTE-effects are modified. These effects increase with inceasing ratio sigma/v(therm).

  10. openBEB: open biological experiment browser for correlative measurements

    PubMed Central

    2014-01-01

    Background New experimental methods must be developed to study interaction networks in systems biology. To reduce biological noise, individual subjects, such as single cells, should be analyzed using high throughput approaches. The measurement of several correlative physical properties would further improve data consistency. Accordingly, a considerable quantity of data must be acquired, correlated, catalogued and stored in a database for subsequent analysis. Results We have developed openBEB (open Biological Experiment Browser), a software framework for data acquisition, coordination, annotation and synchronization with database solutions such as openBIS. OpenBEB consists of two main parts: A core program and a plug-in manager. Whereas the data-type independent core of openBEB maintains a local container of raw-data and metadata and provides annotation and data management tools, all data-specific tasks are performed by plug-ins. The open architecture of openBEB enables the fast integration of plug-ins, e.g., for data acquisition or visualization. A macro-interpreter allows the automation and coordination of the different modules. An update and deployment mechanism keeps the core program, the plug-ins and the metadata definition files in sync with a central repository. Conclusions The versatility, the simple deployment and update mechanism, and the scalability in terms of module integration offered by openBEB make this software interesting for a large scientific community. OpenBEB targets three types of researcher, ideally working closely together: (i) Engineers and scientists developing new methods and instruments, e.g., for systems-biology, (ii) scientists performing biological experiments, (iii) theoreticians and mathematicians analyzing data. The design of openBEB enables the rapid development of plug-ins, which will inherently benefit from the “house keeping” abilities of the core program. We report the use of openBEB to combine live cell microscopy

  11. Noise Suppression on the Tunable Laser for Precise Cavity Length Displacement Measurement.

    PubMed

    Šmíd, Radek; Čížek, Martin; Mikel, Břetislav; Hrabina, Jan; Lazar, Josef; Číp, Ondřej

    2016-01-01

    The absolute distance between the mirrors of a Fabry-Perot cavity with a spacer from an ultra low expansion material was measured by an ultra wide tunable laser diode. The DFB laser diode working at 1542 nm with 1.5 MHz linewidth and 2 nm tuning range has been suppressed with an unbalanced heterodyne fiber interferometer. The frequency noise of laser has been suppressed by 40 dB across the Fourier frequency range 30-300 Hz and by 20 dB up to 4 kHz and the linewidth of the laser below 300 kHz. The relative resolution of the measurement was 10 - 9 that corresponds to 0.3 nm (sub-nm) for 0.178 m long cavity with ability of displacement measurement of 0.5 mm. PMID:27608024

  12. Maize Varieties Released in Different Eras Have Similar Root Length Density Distributions in the Soil, Which Are Negatively Correlated with Local Concentrations of Soil Mineral Nitrogen

    PubMed Central

    Ning, Peng; Li, Sa; White, Philip J.; Li, Chunjian

    2015-01-01

    Larger, and deeper, root systems of new maize varieties, compared to older varieties, are thought to have enabled improved acquisition of soil resources and, consequently, greater grain yields. To compare the spatial distributions of the root systems of new and old maize varieties and their relationships with spatial variations in soil concentrations of available nitrogen (N), phosphorus (P) and potassium (K), two years of field experiments were performed using six Chinese maize varieties released in different eras. Vertical distributions of roots, and available N, P and K in the 0–60 cm soil profile were determined in excavated soil monoliths at silking and maturity. The results demonstrated that new maize varieties had larger root dry weight, higher grain yield and greater nutrient accumulation than older varieties. All varieties had similar total root length and vertical root distribution at silking, but newer varieties maintained greater total root length and had more roots in the 30–60 cm soil layers at maturity. The spatial variation of soil mineral N (Nmin) in each soil horizon was larger than that of Olsen-P and ammonium-acetate-extractable K, and was inversely correlated with root length density (RLD), especially in the 0–20 cm soil layer. It was concluded that greater acquisition of mineral nutrients and higher yields of newer varieties were associated with greater total root length at maturity. The negative relationship between RLD and soil Nmin at harvest for all varieties suggests the importance of the spatial distribution of the root system for N uptake by maize. PMID:25799291

  13. Correlation of environmental data measurements with polarimetric LWIR sensor measurements of manmade objects in natural clutter

    NASA Astrophysics Data System (ADS)

    McCarthy, James; Woolley, Mark; Roth, Luz

    2010-04-01

    In recent years there has been an increased interest in using polarimetric imaging sensors for terrestrial remote sensing applications because of their ability to discriminate manmade objects in a natural clutter background. However, adverse weather limits the performance of these sensors. Long Wave Infrared (LWIR) polarimetric sensor data of a scene containing manmade objects in a natural clutter background is compared with simultaneously collected environmental data. In this paper, a metric is constructed from the Stokes parameter S1 and is correlated with some environmental channels. There are differences in the correlation outputs, with the sensor data metric positively correlated with some environmental channels, negatively correlated with some channels and uncorrelated with other channels. Results from real data measurements are presented and interpreted. An uncooled LWIR sensor using an achromatic retarder to capture the polarimetric states performed the data collection. The environmental channels include various meteorological channels, radiation loading and soil properties.

  14. The spin Hall angle and spin diffusion length of Pd measured by spin pumping and microwave photoresistance

    SciTech Connect

    Tao, X. D.; Feng, Z.; Miao, B. F.; Sun, L.; You, B.; Wu, D.; Du, J.; Zhang, W.; Ding, H. F.

    2014-05-07

    We present the experimental study of the spin Hall angle (SHA) and spin diffusion length of Pd with the spin pumping and microwave photoresistance effects. The Py/Pd bilayer stripes are excited with an out-of-plane microwave magnetic field. The pure spin current is thus pumped and transforms into charge current via the inverse spin Hall effect (ISHE) in Pd layer, yielding an ISHE voltage. The ISHE voltage can be distinguished from the unwanted signal caused by the anisotropic magnetoresistance according to their different symmetries. Together with Pd thickness dependent measurements of in and out-of-plane precessing angles and effective spin mixing conductance, the SHA and spin-diffusion length of Pd are quantified as 0.0056 ± 0.0007 and 7.3 ± 0.7 nm, respectively.

  15. 16 CFR 500.12 - Measurement of commodities by length and width, how expressed.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... width, how expressed. 500.12 Section 500.12 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENT OF GENERAL POLICY OR INTERPRETATION AND EXEMPTIONS UNDER THE FAIR PACKAGING AND LABELING ACT REGULATIONS UNDER SECTION 4 OF THE FAIR PACKAGING AND LABELING ACT § 500.12 Measurement...

  16. 16 CFR 500.11 - Measurement of commodity length, how expressed.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... expressed. 500.11 Section 500.11 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENT OF GENERAL POLICY OR INTERPRETATION AND EXEMPTIONS UNDER THE FAIR PACKAGING AND LABELING ACT REGULATIONS UNDER SECTION 4 OF THE FAIR PACKAGING AND LABELING ACT § 500.11 Measurement of commodity...

  17. 16 CFR 500.12 - Measurement of commodities by length and width, how expressed.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... width, how expressed. 500.12 Section 500.12 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENT OF GENERAL POLICY OR INTERPRETATION AND EXEMPTIONS UNDER THE FAIR PACKAGING AND LABELING ACT REGULATIONS UNDER SECTION 4 OF THE FAIR PACKAGING AND LABELING ACT § 500.12 Measurement...

  18. 16 CFR 500.12 - Measurement of commodities by length and width, how expressed.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... dimension of less than 2 feet (60.96 cm) may be stated in inches. (4) For any commodity for which the... LABELING ACT REGULATIONS UNDER SECTION 4 OF THE FAIR PACKAGING AND LABELING ACT § 500.12 Measurement of... a width of more than 4 inches (10.1 cm) shall: (1) When the commodity has an area of less than...

  19. Evaluation of Length-of-Stain Gas Indicator Tubes for Measuring Carbon Monoxide in Air.

    ERIC Educational Resources Information Center

    Klaubert, Earl C.; And Others

    Techniques for detection and measurement of carbon monoxide (CO) in air are of interest and utility in many aspects of automotive safety. CO concentrations may range from less than 100 parts per million (ppm), or 0.01 percent, to about 10 percent by volume. Gas indicator tubes have been used for many years primarily as detectors of hazardous gases…

  20. Correlated Protein Motion Measurements of Dihydrofolate Reductase Crystals

    NASA Astrophysics Data System (ADS)

    Xu, Mengyang; Niessen, Katherine; Pace, James; Cody, Vivian; Markelz, Andrea

    2014-03-01

    We report the first direct measurements of the long range structural vibrational modes in dihydrofolate reductase (DHFR). DHFR is a universal housekeeping enzyme that catalyzes the reduction of 7,8-dihydrofolate to 5,6,7,8-tetra-hydrofolate, with the aid of coenzyme nicotinamide adenine dinucleotide phosphate (NADPH). This crucial enzymatic role as the target for anti-cancer [methotrexate (MTX)], and other clinically useful drugs, has made DHFR a long-standing target of enzymological studies. The terahertz (THz) frequency range (5-100 cm-1), corresponds to global correlated protein motions. In our lab we have developed Crystal Anisotropy Terahertz Microscopy (CATM), which directly measures these large scale intra-molecular protein vibrations, by removing the relaxational background of the solvent and residue side chain librational motions. We demonstrate narrowband features in the anisotropic absorbance for mouse DHFR with the ligand binding of NADPH and MTX single crystals as well as Escherichia coli DHFR with the ligand binding of NADPH and MTX single crystals. This work is supported by NSF grant MRI2 grant DBI2959989.

  1. Flap noise characteristics measured by pressure cross correlation techniques

    NASA Astrophysics Data System (ADS)

    Miller, W. R.

    1980-03-01

    The aerodynamic sound generated by a realistic aircraft flap system was investigated through the use of cross correlations between surface pressure fluctuations and far field sound. Measurements were conducted in two subsonic wind tunnel studies to determine the strength, distribution, and directivity of the major sources of flap noise at speeds up to 79.0 m/sec. A pilot study was performed on a single flap model to test the measurement technique and provide initial data on the characteristics of flap noise. The major portion of this investigation studied the sound radiated by a realistic large scale model of a triple slotted flap system mounted on a sweptback 6.7 meter semispan model wing. The results of this investigation have identified the major sources of flap generated noise and their dependence of flow defining parameters. In addition, a possible avenue toward the reduction of flap generated noise has been identified via the placement of the flap actuator fairings on the flap system.

  2. Theoretical predictions for spatial covariance of the electroencephalographic signal during the anesthetic-induced phase transition: Increased correlation length and emergence of spatial self-organization

    NASA Astrophysics Data System (ADS)

    Steyn-Ross, Moira L.; Steyn-Ross, D. A.; Sleigh, J. W.; Whiting, D. R.

    2003-08-01

    In a recent series of papers, the authors have developed a stochastic theory to describe the electrical response of a spatially homogeneous cerebral cortex to infusion of a general anesthetic agent. We showed that by modeling the GABAergic (propofol-like) drug effect as a prolongation of the inhibitory postsynaptic impulse response, we obtain a prediction that there will be a hysteretically separated pair of first-order phase transitions in the population-average excitatory soma voltage, the first occurring at the point of induction of unconsciousness, and the second at the point of emergence from unconsciousness. In the present paper we generalize our earlier “zero-dimensional” homogeneous cortex to a one-dimensional (1D) line of cortical “mass,” thus allowing for the possibility of spatial inhomogeneities in neural activity. Following the spirit of our earlier adiabatic (“slow membrane”) philosophy, we impose a spatioadiabatic approximation that permits us to compute analytic expressions for changes in EEG (electroencephalographic) correlation length and EEG spatial covariance as a function of anesthetic effect. We establish that the correlation length of the EEG fluctuations is expected to increase at the approach to the transition points, and this finding is consistent with both the homogeneous-cortex prediction of increased correlation time (“critical slowing down”) near transition, and the recent, comprehensive anesthetic study by John et al. [Conscious. Cogn. 10, 165 (2001)] reporting an increase in EEG coherence near the points of loss and recovery of consciousness. In addition, we find that if the long-range (corticocortical) excitatory-to-inhibitory connectivity in the 1D cortex is stronger than the long-range excitatory-to-excitatory connectivity, then the spatioadiabatic system can organize itself into large-amplitude spatial patterns (“dissipative structures”) consisting of giant stationary quasiperiodic voltage fluctuations

  3. Three-dimensional fiber probe based on orthogonal micro focal-length collimation for the measurement of micro parts.

    PubMed

    Cui, Jiwen; Li, Junying; Feng, Kunpeng; Tan, Jiubin

    2015-10-01

    A 3-dimensional fiber probe based on orthogonal micro focal-length collimation (MFL-collimation) is proposed for the measurement of micro parts with high aspect ratios. The probe consists of a fiber stylus which acts as a micro focal-length cylindrical lens (MFLC-lens) of the two orthogonal MFL-collimation optical paths and a probe tip fixed on the free end of the fiber stylus for touching the workpiece. The fiber stylus will deflect (deflection mode) or buckle (buckling mode) under contacts, and the deflection or buckling of the fiber stylus will cause corresponding shifts of the fringe images of the two orthogonal MFL-collimation optical paths. Therefore, the 3-dimensional displacements of the probe tip are transformed into the centroid position shifts of the zero-order fringe images. Experimental results indicate that the fiber probe has a measuring capability in 3-dimensional tactility, and a radial and axial resolution of 5 nm and 3 nm can be obtained respectively. The probe is easily applied in the measurement of micro parts because of its high resolution, low cost, high measurable aspect ratio, low probing forces and capability in three-dimensional tactility. PMID:26480152

  4. Partially correlated azimuthal vortex illumination: coherence and correlation measurements and effects in imaging.

    PubMed

    Brown, Dean P; Brown, Thomas G

    2008-12-01

    Correlations in the illumination field have a profound impact on the image contrast for features near the resolution limit. The pupil polarization affects these correlations. We show that a polarization vortex has a particularly dramatic effect. A theoretical model is given for the correlation matrix of a partially correlated source created by placing an azimuthal polarization vortex mode converter in the pupil plane of a critical illumination system. We then validate this model experimentally using a reversed-wavefront Young interferometer, directly show the impact that the phase of the correlation function has on image contrast. PMID:19065180

  5. LIGHT SOURCE: RF deflecting cavity for bunch length measurement in Tsinghua Thomson scattering X-ray source

    NASA Astrophysics Data System (ADS)

    Shi, Jia-Ru; Chen, Huai-Bi; Tang, Chuan-Xiang; Huang, Wen-Hui; Du, Ying-Chao; Zheng, Shu-Xin; Ren, Li

    2009-06-01

    An RF deflecting cavity used for bunch length measurement has been designed and fabricated at Tsinghua University for the Thomson Scattering X-Ray Source. The cavity is a 2856 MHz, π-mode, 3-cell standing-wave cavity, to diagnose the 3.5 MeV beam produced by photocathode electron gun. With a larger power source, the same cavity will again be used to measure the accelerated beam with energy of 50 MeV before colliding with the laser pulse. The RF design using MAFIA for both the cavity shape and the power coupler is reviewed, followed by presenting the fabrication procedure and bench measurement results of two cavities.

  6. Inter-ELM power decay length for JET and ASDEX upgrade: measurement and comparison with heuristic drift-based model.

    PubMed

    Eich, T; Sieglin, B; Scarabosio, A; Fundamenski, W; Goldston, R J; Herrmann, A

    2011-11-18

    Experimental measurements of the SOL power decay length (λ(q)) estimated from analysis of fully attached divertor heat load profiles from two tokamaks, JET and ASDEX Upgrade, are presented. Data was measured by means of infrared thermography. An empirical scaling reveals parametric dependency λ(q) in mm = 0.73B(T)(-0.78)q(cyl)(1.2)P(SOL)(0.1)R(geo)(0), where B(T)(T) describes the toroidal magnetic field, q(cyl) the cylindrical safety factor, P(SOL)(MW) the power crossing the separatrix and R(geo)(m) the major radius of the device. A comparison of these measurements to a heuristic particle drift-based model shows satisfactory agreement in both absolute magnitude and scaling. Extrapolation to ITER gives λ(q) ≃ 1 mm. PMID:22181888

  7. Effects of parental origins and length of residency on adiposity measures and nutrition in urban middle school students: a cross-sectional study

    PubMed Central

    2013-01-01

    Background The prevalence of obesity in U.S. has been rising at an alarming rate, particularly among Hispanic, African, and Asian minority groups. This trend is due in part to excessive calorie consumption and sedentary lifestyle. We sought to investigate whether parental origins influence eating behaviors in healthy urban middle school students. Methods A multiethnic/racial population of students (N = 182) enrolled in the ROAD (Reduce Obesity and Diabetes) Study, a school-based trial to assess clinical, behavioral, and biochemical risk factors for adiposity and its co-morbidities completed questionnaires regarding parental origins, length of US residency, and food behaviors and preferences. The primary behavioral questionnaire outcome variables were nutrition knowledge, attitude, intention and behavior, which were then related to anthropometric measures of waist circumference, BMI z-scores, and percent body fat. Two-way analysis of variance was used to evaluate the joint effects of number of parents born in the U.S. and ethnicity on food preference and knowledge score. The Tukey-Kramer method was used to compute pairwise comparisons to determine where differences lie. Analysis of covariance (ANCOVA) was used to analyze the joint effects of number of parents born in the US and student ethnicity, along with the interaction term, on each adiposity measure outcome. Pearson correlation coefficients were used to examine the relationships between maternal and paternal length of residency in the US with measures of adiposity, food preference and food knowledge. Results African Americans had significantly higher BMI, waist circumference and body fat percentage compared to other racial and ethnic groups. Neither ethnicity/race nor parental origins had an impact on nutrition behavior. Mothers’ length of US residency positively correlated with students’ nutrition knowledge, but not food attitude, intention or behavior. Conclusions Adiposity measures in children differ

  8. Quantitative measurement of full-length and C-terminal proteolyzed RBP4 in serum of normal and insulin-resistant humans using a novel mass spectrometry immunoassay.

    PubMed

    Yang, Qin; Eskurza, Iratxe; Kiernan, Urban A; Phillips, David A; Blüher, Matthias; Graham, Timothy E; Kahn, Barbara B

    2012-03-01

    Serum retinol-binding protein 4 (RBP4) levels are increased in insulin-resistant humans and correlate with severity of insulin resistance in metabolic syndrome. Quantitative Western blotting (qWestern) has been the most accurate method for serum RBP4 measurements, but qWestern is technically complex and labor intensive. The lack of a reliable, high-throughput method for RBP4 measurements has resulted in variability in findings in insulin-resistant humans. Many commonly used ELISAs have limited dynamic range. Neither the current ELISAs nor qWestern distinguish among full-length and carboxyl terminus proteolyzed forms of circulating RBP4 that are altered in different medical conditions. Here, we report the development of a novel quantitative mass spectrometry immunoaffinity assay (qMSIA) to measure full-length and proteolyzed forms of RBP4. qMSIA and qWestern of RBP4 were performed in identical serum aliquots from insulin-sensitive/normoglycemic or insulin-resistant humans with impaired glucose tolerance or type 2 diabetes. Total RBP4 qMSIA measurements were highly similar to qWestern and correlated equally well with clinical severity of insulin resistance (assessed by clamp glucose disposal rate, r = -0.74), hemoglobin A1c (r = 0.63), triglyceride/high-density lipoprotein (r = 0.55), waist/hip (r = 0.61), and systolic blood pressure (r = 0.53, all P < 0.001). Proteolyzed forms of RBP4 accounted for up to 50% of total RBP4 in insulin-resistant subjects, and des(Leu)-RBP4 (cleavage of last leucine) correlated highly with insulin resistance (assessed by glucose disposal rate, r = -0.69). In multiple regression analysis, insulin resistance but not glomerular filtration rate was the strongest, independent predictor of serum RBP4 levels. Thus, qMSIA provides a novel tool for accurately measuring serum RBP4 levels as a biomarker for severity of insulin resistance and risk for type 2 diabetes and metabolic syndrome. PMID:22253430

  9. Similarity analysis between chromosomes of Homo sapiens and monkeys with correlation coefficient, rank correlation coefficient and cosine similarity measures.

    PubMed

    Someswara Rao, Chinta; Viswanadha Raju, S

    2016-03-01

    In this paper, we consider correlation coefficient, rank correlation coefficient and cosine similarity measures for evaluating similarity between Homo sapiens and monkeys. We used DNA chromosomes of genome wide genes to determine the correlation between the chromosomal content and evolutionary relationship. The similarity among the H. sapiens and monkeys is measured for a total of 210 chromosomes related to 10 species. The similarity measures of these different species show the relationship between the H. sapiens and monkey. This similarity will be helpful at theft identification, maternity identification, disease identification, etc. PMID:26981409

  10. Measuring myosin cross-bridge attachment time in activated muscle fibers using stochastic vs. sinusoidal length perturbation analysis

    PubMed Central

    Wang, Yuan; Maughan, David W.; Palmer, Bradley M.

    2011-01-01

    The average time myosin cross bridges remain bound to actin (ton) can be measured by sinusoidal length perturbations (sinusoidal analysis) of striated muscle fibers using recently developed analytic methods. This approach allows measurements of ton in preparations possessing a physiologically relevant myofilament lattice. In this study, we developed an approach to measure ton in 5–10% of the time required for sinusoidal analysis by using stochastic length perturbations (white noise analysis). To compare these methods, we measured the influence of MgATP concentration ([MgATP]) on ton in demembranated myocardial strips from mice, sampling muscle behavior from 0.125 to 200 Hz with a 20-s burst of white noise vs. a 300-s series of sinusoids. Both methods detected a similar >300% increase in ton as [MgATP] decreased from 5 to 0.25 mM, differing by only 3–14% at any [MgATP]. Additional experiments with Drosophila indirect flight muscle fibers demonstrated that faster cross-bridge cycling kinetics permit further reducing of the perturbation time required to measure ton. This reduced sampling time allowed strain-dependent measurements of ton in flight muscle fibers by combining 10-s bursts of white noise during periods of linear shortening and lengthening. Analyses revealed longer ton values during shortening and shorter ton values during lengthening. This asymmetry may provide a mechanism that contributes to oscillatory energy transfer between the flight muscles and thoracic cuticle to power flight. This study demonstrates that white noise analysis can detect underlying molecular processes associated with dynamic muscle contraction comparable to sinusoidal analysis, but in a fraction of the time. PMID:21233339

  11. Measurement and correlates of empathy among female Japanese physicians

    PubMed Central

    2012-01-01

    Background The measurement of empathy is important in the assessment of physician competence and patient outcomes. The prevailing view is that female physicians have higher empathy scores compared with male physicians. In Japan, the number of female physicians has increased rapidly in the past ten years. In this study, we focused on female Japanese physicians and addressed factors that were associated with their empathic engagement in patient care. Methods The Jefferson Scale of Empathy (JSE) was translated into Japanese by using the back-translation procedure, and was administered to 285 female Japanese physicians. We designed this study to examine the psychometrics of the JSE and group differences among female Japanese physicians. Results The item-total score correlations of the JSE were all positive and statistically significant, ranging from .20 to .54, with a median of .41. The Cronbach’s coefficient alpha was .81. Female physicians who were practicing in “people-oriented” specialties obtained a significantly higher mean empathy score than their counterparts in “procedure-” or “technology-oriented” specialties. In addition, physicians who reported living with their parents in an extended family or living close to their parents, scored higher on the JSE than those who were living alone or in a nuclear family. Conclusions Our results provide support for the measurement property and reliability of the JSE in a sample of female Japanese physicians. The observed group differences associated with specialties and living arrangement may have implications for sustaining empathy. In addition, recognizing these factors that reinforce physicians’ empathy may help physicians to avoid career burnout. PMID:22726449

  12. An Evolutionarily Conserved Family of Virion Tail Needles Related to Bacteriophage P22 gp26: Correlation between Structural Stability and Length of the -Helical Trimeric Coiled Coil

    SciTech Connect

    Bhardwaj, A.; Walker-Kopp, N; Casjens, S; Cingolani, G

    2009-01-01

    Bacteriophages of the Podoviridae family use short noncontractile tails to inject their genetic material into Gram-negative bacteria. In phage P22, the tail contains a thin needle, encoded by the phage gene 26, which is essential both for stabilization and for ejection of the packaged viral genome. Bioinformatic analysis of the N-terminal domain of gp26 (residues 1-60) led us to identify a family of genes encoding putative homologues of the tail needle gp26. To validate this idea experimentally and to explore their diversity, we cloned the gp26-like gene from phages HK620, Sf6 and HS1, and characterized these gene products in solution. All gp26-like factors contain an elongated {alpha}-helical coiled-coil core consisting of repeating, adjacent trimerization heptads and form trimeric fibers with length ranging between about 240 to 300 {angstrom}. gp26 tail needles display a high level of structural stability in solution, with Tm (temperature of melting) between 85 and 95 C. To determine how the structural stability of these phage fibers correlates with the length of the {alpha}-helical core, we investigated the effect of insertions and deletions in the helical core. In the P22 tail needle, we identified an 85-residue-long helical domain, termed MiCRU (minimal coiled-coil repeat unit), that can be inserted in-frame inside the gp26 helical core, preserving the straight morphology of the fiber. Likewise, we were able to remove three quarters of the helical core of the HS1 tail needle, minimally decreasing the stability of the fiber. We conclude that in the gp26 family of tail needles, structural stability increases nonlinearly with the length of the {alpha}-helical core. Thus, the overall stability of these bacteriophage fibers is not solely dependent on the number of trimerization repeats in the {alpha}-helical core.

  13. Spreading lengths of Hermite polynomials

    NASA Astrophysics Data System (ADS)

    Sánchez-Moreno, P.; Dehesa, J. S.; Manzano, D.; Yáñez, R. J.

    2010-03-01

    The Renyi, Shannon and Fisher spreading lengths of the classical or hypergeometric orthogonal polynomials, which are quantifiers of their distribution all over the orthogonality interval, are defined and investigated. These information-theoretic measures of the associated Rakhmanov probability density, which are direct measures of the polynomial spreading in the sense of having the same units as the variable, share interesting properties: invariance under translations and reflections, linear scaling and vanishing in the limit that the variable tends towards a given definite value. The expressions of the Renyi and Fisher lengths for the Hermite polynomials are computed in terms of the polynomial degree. The combinatorial multivariable Bell polynomials, which are shown to characterize the finite power of an arbitrary polynomial, play a relevant role for the computation of these information-theoretic lengths. Indeed these polynomials allow us to design an error-free computing approach for the entropic moments (weighted Lq-norms) of Hermite polynomials and subsequently for the Renyi and Tsallis entropies, as well as for the Renyi spreading lengths. Sharp bounds for the Shannon length of these polynomials are also given by means of an information-theoretic-based optimization procedure. Moreover, the existence of a linear correlation between the Shannon length (as well as the second-order Renyi length) and the standard deviation is computationally proved. Finally, the application to the most popular quantum-mechanical prototype system, the harmonic oscillator, is discussed and some relevant asymptotical open issues related to the entropic moments, mentioned previously, are posed.

  14. PRIOR GENETIC CORRELATIONS AND NON-MEASURED TRAITS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Current international genetic evaluations are based on how related country populations are genetically (across-country genetic correlations). Those correlations may be influenced strongly by prior expectations that were not based on sound scientific principles. Objective methods to predict prior cor...

  15. On-line qualification of a micro probing system for precision length measurement of micro-features on precision parts

    NASA Astrophysics Data System (ADS)

    Chen, Yuan-Liu; Ito, So; Kikuchi, Hirotaka; Kobayashi, Ryo; Shimizu, Yuki; Gao, Wei

    2016-07-01

    This paper presents on-line qualification of the effective diameter of the micro-stylus tip ball of a micro probing system for precision length measurement of micro-features on precision parts by utilizing a set of gauge blocks as the qualification artefact, which is composed by one calibrated gauge block and two supporting gauge blocks that are wrung together for a good mechanical stability. The qualification artefact is aligned side by side with the precision part to be measured for enabling a rapid transfer between the qualification step of the probe two-point tip ball diameter and the length measurement step of the precision part. Based on the proposed setup, on-line qualifications of a micro-stylus with a nominal tip ball diameter of 52.6 μm were carried out by using two methods referred to as Method A and Method B, respectively. Method A is operated by probing the opposite sides of the gap between the two supporting gauge blocks separated by the calibrated gauge block, and Method B is operated by probing the opposite sides of the calibrated gauge block supported by the two supporting gauge blocks. Intensive uncertainty analyses based on the experimental results and the geometrical models were carried out to compare the performances of these two methods. Method A, which was confirmed to be more accurate and faster than Method B, was then employed to measure the width of a micro-gap on a precision part with compensation of the determined effective two-point tip ball diameter.

  16. Measuring Black Smoker Fluid Flow Rates Using Image Correlation Velocimetry

    NASA Astrophysics Data System (ADS)

    Crone, T. J.; Wilcock, W. S.; McDuff, R. E.

    2006-12-01

    Motivated by a desire to find non-invasive methods for obtaining time-series measurements of fluid flow rates through mid-ocean ridge black smokers, we are developing an image-based velocimetry technique that will provide this information through the analysis of video sequences showing the turbulent structures of black smoker effluent jets. Our ultimate goal is to develop an autonomous seafloor instrument suitable for use with a cabled seafloor observatory that can provide extended time-series measurements of black smoker discharge rates with little user intervention. The method we are developing is based on the two-dimensional cross-correlation of an array of overlapping subimages from two sequential image frames within a sequence. For each pair of images this yields a two- dimensional representation of the instantaneous velocity field in the imaged flow. For each video sequence, the set of these "image velocity fields" from all image pairs is temporally averaged to yield a smoothed representation of the time-averaged image flow field. A transformation is then applied to convert the image flow fields into a relative discharge rate. We have developed a computational algorithm to implement this technique and have successfully applied it to video sequences collected in the late 1980s and early 1990s showing the discharge of black smokers in the Main Endeavour field of the Juan de Fuca Ridge over the course of weeks and months. We are able to resolve velocity fields that are qualitatively consistent with those predicted by plume theory from 5 seconds of video (150 image pairs), but it is difficult to calibrate or assess the precision of the technique with field data alone. In order to address these issues, as well as refine the computational algorithm, we have conducted laboratory simulations of black smoker jets with known discharge rates over a range of Reynolds numbers. We have recorded these simulations to obtain video image sequences that are similar to those

  17. Effectively classically correlated state of a measured system and a bosonic measurement apparatus

    SciTech Connect

    Camalet, S.

    2011-04-15

    We consider a multilevel system coupled to a bosonic measurement apparatus. We derive exact expressions for the time-dependent expectation values of a large class of physically relevant observables that depend on degrees of freedom of both systems. We find that, for this class, though the two systems become entangled as a result of their interaction, they appear classically correlated for long enough times. The unique corresponding time-dependent separable state is determined explicitly. To better understand the physical parameters that control the time scale of this effective disentanglement process, we study a one-dimensional measurement apparatus.

  18. Leaf vein length per unit area is not intrinsically dependent on image magnification: avoiding measurement artifacts for accuracy and precision.

    PubMed

    Sack, Lawren; Caringella, Marissa; Scoffoni, Christine; Mason, Chase; Rawls, Michael; Markesteijn, Lars; Poorter, Lourens

    2014-10-01

    Leaf vein length per unit leaf area (VLA; also known as vein density) is an important determinant of water and sugar transport, photosynthetic function, and biomechanical support. A range of software methods are in use to visualize and measure vein systems in cleared leaf images; typically, users locate veins by digital tracing, but recent articles introduced software by which users can locate veins using thresholding (i.e. based on the contrasting of veins in the image). Based on the use of this method, a recent study argued against the existence of a fixed VLA value for a given leaf, proposing instead that VLA increases with the magnification of the image due to intrinsic properties of the vein system, and recommended that future measurements use a common, low image magnification for measurements. We tested these claims with new measurements using the software LEAFGUI in comparison with digital tracing using ImageJ software. We found that the apparent increase of VLA with magnification was an artifact of (1) using low-quality and low-magnification images and (2) errors in the algorithms of LEAFGUI. Given the use of images of sufficient magnification and quality, and analysis with error-free software, the VLA can be measured precisely and accurately. These findings point to important principles for improving the quantity and quality of important information gathered from leaf vein systems. PMID:25096977

  19. Joint radius-length distribution as a measure of anisotropic pore eccentricity: An experimental and analytical framework

    PubMed Central

    Benjamini, Dan; Basser, Peter J.

    2014-01-01

    In this work, we present an experimental design and analytical framework to measure the nonparametric joint radius-length (R-L) distribution of an ensemble of parallel, finite cylindrical pores, and more generally, the eccentricity distribution of anisotropic pores. Employing a novel 3D double pulsed-field gradient acquisition scheme, we first obtain both the marginal radius and length distributions of a population of cylindrical pores and then use these to constrain and stabilize the estimate of the joint radius-length distribution. Using the marginal distributions as constraints allows the joint R-L distribution to be reconstructed from an underdetermined system (i.e., more variables than equations), which requires a relatively small and feasible number of MR acquisitions. Three simulated representative joint R-L distribution phantoms corrupted by different noise levels were reconstructed to demonstrate the process, using this new framework. As expected, the broader the peaks in the joint distribution, the less stable and more sensitive to noise the estimation of the marginal distributions. Nevertheless, the reconstruction of the joint distribution is remarkably robust to increases in noise level; we attribute this characteristic to the use of the marginal distributions as constraints. Axons are known to exhibit local compartment eccentricity variations upon injury; the extent of the variations depends on the severity of the injury. Nonparametric estimation of the eccentricity distribution of injured axonal tissue is of particular interest since generally one cannot assume a parametric distribution a priori. Reconstructing the eccentricity distribution may provide vital information about changes resulting from injury or that occurred during development. PMID:25481136

  20. Measuring spin correlations in optical lattices using superlattice potentials

    SciTech Connect

    Pedersen, K. G. L.; Andersen, B. M.; Soerensen, A. S.; Bruun, G. M.; Syljuaasen, O. F.

    2011-10-15

    We suggest two experimental methods for probing both short- and long-range spin correlations of atoms in optical lattices using superlattice potentials. The first method involves an adiabatic doubling of the periodicity of the underlying lattice to probe neighboring singlet (triplet) correlations for fermions (bosons) by the occupation of the resulting vibrational ground state. The second method utilizes a time-dependent superlattice potential to generate spin-dependent transport by any number of prescribed lattice sites, and probes correlations by the resulting number of doubly occupied sites. For experimentally relevant parameters, we demonstrate how both methods yield large signatures of antiferromagnetic correlations of strongly repulsive fermionic atoms in a single shot of the experiment. Lastly, we show how this method may also be applied to probe d-wave pairing, a possible ground-state candidate for the doped repulsive Hubbard model.

  1. Full field strain measurements of collagenous tissue by tracking fiber alignment through vector correlation.

    PubMed

    Quinn, Kyle P; Winkelstein, Beth A

    2010-09-17

    Full field strain measurements of biological tissue during loading are often limited to the quantification of fiduciary marker displacements on the tissue surface. These marker measurements can lack the necessary spatial resolution to characterize non-uniform deformation and may not represent the deformation of the load-bearing collagen microstructure. To overcome these potential limitations, a method was developed to track the deformation of the collagen fiber microstructure in ligament tissue. Using quantitative polarized light imaging, fiber alignment maps incorporating both direction and alignment strength at each pixel were generated during facet capsular ligament loading. A grid of virtual markers was superimposed over the tissue in the alignment maps, and the maximization of a vector correlation calculation between fiber alignment maps was used to track marker displacement. Tracking error was quantified through comparisons to the displacements of excised ligament tissue (n=3); separate studies applied uniaxial tension to isolated facet capsular ligament tissue (n=4) to evaluate tracking capabilities during large tissue deformations. The average difference between virtual marker and tissue displacements was 0.07+/-0.06pixels. This error in marker location produced principal strain measurements of 1.2+/-1.6% when markers were spaced 4pixels apart. During tensile tissue loading, substantial inhomogeneity was detected in the strain field using vector correlation tracking, and the location of maximum strain differed from that produced by standard tracking techniques using coarser meshes. These findings provide a method to directly measure fiber network strains using quantitative fiber alignment data, enabling a better understanding of structure-function relationships in tissues at different length scales. PMID:20494363

  2. Theory and Measurement of Partially Correlated Persistent Scatterers

    NASA Astrophysics Data System (ADS)

    Lien, J.; Zebker, H. A.

    2011-12-01

    Interferometric synthetic aperture radar (InSAR) time-series methods can effectively estimate temporal surface changes induced by geophysical phenomena. However, such methods are susceptible to decorrelation due to spatial and temporal baselines (radar pass separation), changes in orbital geometries, atmosphere, and noise. These effects limit the number of interferograms that can be used for differential analysis and obscure the deformation signal. InSAR decorrelation effects may be ameliorated by exploiting pixels that exhibit phase stability across the stack of interferograms. These so-called persistent scatterer (PS) pixels are dominated by a single point-like scatterer that remains phase-stable over the spatial and temporal baseline. By identifying a network of PS pixels for use in phase unwrapping, reliable deformation measurements may be obtained even in areas of low correlation, where traditional InSAR techniques fail to produce useful observations. PS identification is challenging in natural terrain, due to low reflectivity and few corner reflectors. Shanker and Zebker [1] proposed a PS pixel selection technique based on maximum-likelihood estimation of the associated signal-to-clutter ratio (SCR). In this study, we further develop the underlying theory for their technique, starting from statistical backscatter characteristics of PS pixels. We derive closed-form expressions for the spatial, rotational, and temporal decorrelation of PS pixels as a function of baseline and signal-to-clutter ratio. We show that previous decorrelation and critical baseline expressions [2] are limiting cases of our result. We then describe a series of radar scattering simulations and show that the simulated decorrelation matches well with our analytic results. Finally, we use our decorrelation expressions with maximum-likelihood SCR estimation to analyze an area of the Hayward Fault Zone in the San Francisco Bay Area. A series of 38 images of the area were obtained from C

  3. Two-dimensional tissue tracking: a novel echocardiographic technique to measure left atrial volume: comparison with biplane area length method and real time three-dimensional echocardiography.

    PubMed

    Li, Shi-Yan; Zhang, Li; Zhao, Bo-Wen; Yu, Chan; Xu, Li-Long; Li, Peng; Xu, Ke; Pan, Mei; Wang, Bei

    2014-07-01

    Enlargement of the left atrium is an independent predictor of adverse cardiovascular outcomes, and an accurate, convenient imaging modality is necessary for clinical practice. The objectives of this study were to evaluate the feasibility of a novel imaging technique, two-dimensional tissue tracking (2DTT), for assessment of left atrial (LA) volume and function and to compare its correlation and agreement with biplane area length (AL) method and real time three-dimensional echocardiography (RT3DE). A total of 105 patients prospectively underwent 2DTT, AL and RT3DE. The LA volume index (LAVI) and emptying fraction were measured. In addition, intra- and inter-observer agreement were calculated by using the intraclass correlation coefficient. There were no significant differences in LAVI and emptying fraction measured by 2DTT in comparison with those made by AL or RT3DE, furthermore Bland-Altman analysis showed that 2DTT had significantly better agreement for LAVI and emptying fraction with AL and RT3DE. 2DTT also exhibited smaller intra- and inter-observer variability as compared with AL or RT3DE. Furthermore, the time to measure LA volume and acquire time-volume curve was significantly less by 2DTT than that by RT3DE (U = 49.00, P < 0.001). These observations suggest that the 2DTT could provide valuable information which is consistent with the standard AL and RT3DE measurements for LAVI and function with potentially lower intra- and inter-observer variability. PMID:24460543

  4. Direct visualization and measurement of the extrapolation length on cooling toward the nematic-smectic-A phase transition temperature.

    PubMed

    Choi, Yoonseuk; Rosenblatt, Charles

    2010-05-01

    A herringbone "easy axis" pattern is scribed into a polyimide alignment layer for liquid-crystal orientation using the stylus of an atomic force microscope. Owing to the liquid crystal's bend elasticity K33 , the nematic director is unable to follow the sharp turn in the scribed easy axis, but instead relaxes over an extrapolation length L=K33/W2φ, where W2φ is the quadratic azimuthal anchoring strength coefficient. By immersing a tapered optical fiber into the liquid crystal, illuminating the fiber with polarized light, and scanning the fiber close to the substrate, a visualization and direct measurement of L are obtained on approaching the nematic-smectic- A phase transition temperature T NA from above. L is found to exhibit a sharp pretransitional increase near T NA, consistent with a diverging bend elastic constant. PMID:20866248

  5. Reexamination of the purity entanglement measure: Peculiarities of a truly thermodynamic quantum correlation measure

    NASA Astrophysics Data System (ADS)

    Batle, J.; Ooi, C. H. Raymond; Abdalla, S.

    2015-12-01

    The purity entanglement measure introduced by Los Alamos group a decade ago is reexamined in the light of interesting features. The role played by purity, reaching a real thermodynamic limit, in detecting quantum phase transitions is studied with a different system, the bond-alternating X Y model in an external magnetic field. The properties of this system are described as well. By considering the dynamics of the original X Y model, we observe that nonergodicity is also grasped by the purity measure, in accordance with other quantum correlation measures that have no common physical or mathematical relation. Adiabaticity is not recovered from the dynamic to the static case, in accordance with one of the consequences of the celebrated Kibble-Zurek mechanism.

  6. Non-Markovianity: initial correlations and nonlinear optical measurements

    PubMed Central

    Dijkstra, Arend G.; Tanimura, Yoshitaka

    2012-01-01

    By extending the response function approach developed in nonlinear optics, we analytically derive an expression for the non-Markovianity in the time evolution of a system in contact with a quantum mechanical bath, and find a close connection with the directly observable nonlinear optical response. The result indicates that memory in the bath-induced fluctuations rather than in the dissipation causes non-Markovianity. Initial correlations between states of the system and the bath are shown to be essential for a correct understanding of the non-Markovianity. These correlations are included in our treatment through a preparation function. PMID:22753819

  7. Measurements of neutron effective doses and attenuation lengths for shielding materials at the heavy-ion medical accelerator in Chiba.

    PubMed

    Kumamoto, Yoshikazu; Noda, Yutaka; Sato, Yukio; Kanai, Tatsuaki; Murakami, Takeshi

    2005-05-01

    The effective doses and attenuation lengths for concrete and iron were measured for the design of heavy ion facilities. Neutrons were produced through the reaction of copper, carbon, and lead bombarded by carbon ions at 230 and 400 MeV.A, neon ions at 400 and 600 MeV.A, and silicon ions at 600 and 800 MeV.A. The detectors used were a Linus and a Andersson-Braun-type rem counter and a detector based on the activation of a plastic scintillator. Representative effective dose rates (in units of 10(-8) microSv h(-1) pps(-1) at 1 m from the incident target surface, where pps means particles per second) and the attenuation lengths (in units of m) were 9.4 x 10(4), 0.46 for carbon ions at 230 MeV.A; 8.9 x 10(5), 0.48 for carbon ions at 400 MeV.A; 9.3 x 10(5), 0.48 for neon ions at 400 MeV.A; 3.8 x 10(6), 0.50 for neon ions at 600 MeV.A; 3.9 x 10(6), 0.50 for silicon ions at 600 MeV.A; and 1.1 x 10(7), 0.51 for silicon ions at 800 MeV.A. The attenuation provided by an iron plate approximately 20 cm thick (nearly equal to the attenuation length) corresponded to that of a 50-cm block of concrete in the present energy range. Miscellaneous results, such as the angular distributions of the neutron effective dose, narrow beam attenuation experiments, decay of gamma-ray doses after the bombardment of targets, doses around an irradiation room, order effects in the multi-layer (concrete and iron) shielding, the doses from different targets, the doses measured with a scintillator activation detector, the gamma-ray doses out of walls and the ratio of the response between the Andersson-Braun-type and the Linus rem counters are also reported. PMID:15824595

  8. Potential for measurement of the distribution of DNA folds in complex environments using Correlated X-ray Scattering

    NASA Astrophysics Data System (ADS)

    Schenk, Gundolf; Krajina, Brad; Spakowitz, Andrew; Doniach, Sebastian

    2016-12-01

    In vivo chromosomal behavior is dictated by the organization of genomic DNA at length scales ranging from nanometers to microns. At these disparate scales, the DNA conformation is influenced by a range of proteins that package, twist and disentangle the DNA double helix, leading to a complex hierarchical structure that remains undetermined. Thus, there is a critical need for methods of structural characterization of DNA that can accommodate complex environmental conditions over biologically relevant length scales. Based on multiscale molecular simulations, we report on the possibility of measuring supercoiling in complex environments using angular correlations of scattered X-rays resulting from X-ray free electron laser (xFEL) experiments. We recently demonstrated the observation of structural detail for solutions of randomly oriented metallic nanoparticles [D. Mendez et al., Philos. Trans. R. Soc. B 360 (2014) 20130315]. Here, we argue, based on simulations, that correlated X-ray scattering (CXS) has the potential for measuring the distribution of DNA folds in complex environments, on the scale of a few persistence lengths.

  9. Optical Design of a Broadband Infrared Spectrometer for Bunch Length Measurement at the Linac Coherent Light Source

    SciTech Connect

    Williams, Kiel; /SLAC

    2012-09-07

    The electron pulses generated by the Linac Coherent Light Source at the SLAC National Accelerator Laboratory occur on the order of tens of femtoseconds and cannot be directly measured by conventional means. The length of the pulses can instead be reconstructed by measuring the spectrum of optical transition radiation emitted by the electrons as they move toward a conducting foil. Because the emitted radiation occurs in the mid-infrared from 0.6 to 30 microns a novel optical layout is required. Using a helium-neon laser with wavelength 633 nm, a series of gold-coated off-axis parabolic mirrors were positioned to direct a beam through a zinc selenide prism and to a focus at a CCD camera for imaging. Constructing this layout revealed a number of novel techniques for reducing the aberrations introduced into the system by the off-axis parabolic mirrors. The beam had a recorded radius of less than a millimeter at its final focus on the CCD imager. This preliminary setup serves as a model for the spectrometer that will ultimately measure the LCLS electron pulse duration.

  10. Investigating the nematic--smectic-[ital A] transition by capillary-length measurements near an apparent tricritical point

    SciTech Connect

    Tamblyn, N. ); Oswald, P. ); Miele, A. ); Bechhoefer, J. )

    1995-03-01

    What is the order of the nematic--smectic-[ital A] ([ital NA]) transition The answer to this question has flip-flopped over the years as ever more sophisticated theories and ever more careful experiments have addressed the issue. The Landau theory predicts that the transition can be either first or second order, depending on material parameters. de Gennes and McMillan [Solid State Commun. 10, 753 (1972); Phys. Rev. A 14, 1238 (1971)] showed that nematic fluctuations would drive the transition to first order as the temperature of the [ital NA] transition approached that of the nematic-isotropic transition. Halperin, Lubensky, and Ma [Phys. Rev. Lett. 32, 292 (1974)] (HLM) then argued that the effect of nematic fluctuations is more subtle and concluded that the transition is always at least weakly first order. Monte Carlo simulations indicate, however, that for a large enough nematic range, the transition becomes second order. We investigate the order of the [ital NA] transition experimentally by measuring the capillary length (ratio of the surface tension to the latent heat) near an apparent tricritical point in a binary liquid-crystal mixture. Our measurements confirm the existence of the extra free-energy term predicted by the HLM theory and yield, as a by-product, surface-tension measurements of the [ital NA] interface. Although we cannot currently detect the tricritical point suggested by numerical work, we have not approached any fundamental sensitivity limits either.

  11. Benefits of Time Correlation Measurements for Passive Screening

    NASA Astrophysics Data System (ADS)

    Murer, David; Blackie, Douglas; Peerani, Paolo

    2014-02-01

    The “FLASH Portals Project” is a collaboration between Arktis Radiation Detectors Ltd (CH), the Atomic Weapons Establishment (UK), and the Joint Research Centre (European Commission), supported by the Technical Support Working Group (TSWG). The program's goal was to develop and demonstrate a technology to detect shielded special nuclear materials (SNM) more efficiently and less ambiguously by exploiting time correlation. This study presents experimental results of a two-sided portal monitor equipped with in total 16 4He fast neutron detectors as well as four polyvinyltoluene (PVT) plastic scintillators. All detectors have been synchronized to nanosecond precision, thereby allowing the resolution of time correlations from timescales of tens of microseconds (such as (n, γ) reactions) down to prompt fission correlations directly. Our results demonstrate that such correlations can be detected in a typical radiation portal monitor (RPM) geometry and within operationally acceptable time scales, and that exploiting these signatures significantly improves the performance of the RPM compared to neutron counting. Furthermore, the results show that some time structure remains even in the presence of heavy shielding, thus significantly improving the sensitivity of the detection system to shielded SNM.

  12. Atmospheric pollution measurement by optical cross correlation methods - A concept

    NASA Technical Reports Server (NTRS)

    Fisher, M. J.; Krause, F. R.

    1971-01-01

    Method combines standard spectroscopy with statistical cross correlation analysis of two narrow light beams for remote sensing to detect foreign matter of given particulate size and consistency. Method is applicable in studies of generation and motion of clouds, nuclear debris, ozone, and radiation belts.

  13. The Internal Structure and Correlates of Some School Climate Measures.

    ERIC Educational Resources Information Center

    Gottfredson, Gary D.

    J. M. Richards (1989) has demonstrated that when individuals' reports about environments are aggregated to create environmental measures, the use of coefficient alpha to estimate single occasion reliability can be misleadingly elevated and that alpha cannot distinguish an environmental measure from a "disguised measure of individual differences."…

  14. Correlation analysis of optical absorption cross section and rate coefficient measurements in reacting systems

    SciTech Connect

    Hessler, J.P.; Ogren, P.J.

    1992-08-31

    A technique was developed for determining relative importance and correlation between reactions making up a complex kinetic system. This technique was used to investigate measurements of optical absorption cross sections and the correlation between cross sections and measured rate coefficients. It is concluded that (1) species, initial conditions, and temporal regions may be identified where cross sections may be measured without interference from the kinetic behavior of the observed species and (2) experiments designed to measure rate coefficients will always be correlated with the absorption cross section of the observed species. This correlation may reduce the accuracy of rate coefficient measurements.

  15. Characterization of S -T+ transition dynamics via correlation measurements

    NASA Astrophysics Data System (ADS)

    Dickel, Christian; Foletti, Sandra; Umansky, Vladimir; Bluhm, Hendrik

    2015-09-01

    Nuclear spins are an important source of dephasing for electron spin qubits in GaAs quantum dots. Most studies of their dynamics have focused on the relatively slow longitudinal polarization. We present a semiclassical model and experimental data showing that the dynamics of the transverse hyperfine field can be probed by correlating individual Landau-Zener sweeps across the S -T+ transition of a two-electron spin qubit. The relative Larmor precession of different nuclear spin species leads to oscillations in these correlations, which decay due to dephasing of the nuclei. In the presence of spin-orbit coupling, oscillations with the absolute Larmor frequencies whose amplitude depends on the spin-orbit coupling strength are expected. These oscillations reflect rapid dynamics of the transverse hyperfine field, which are relevant for several qubit control schemes.

  16. Correlated optical measurements and plasmon mapping of silver nanorods

    SciTech Connect

    Guiton, Beth S; Iberi, Vighter; Li, Shuzhou; Leonard, Donovan N; Parish, Chad M; Kotula, Paul G; Varela del Arco, Maria; Schatz, George C.; Pennycook, Stephen J; Camden, Jon P

    2011-01-01

    Plasmonics is a rapidly growing field, yet imaging of the plasmonic modes in complex nanoscale architectures is extremely challenging. Here we obtain spatial maps of the localized surface plasmon modes of high-aspect-ratio silver nanorods using electron energy loss spectroscopy (EELS) and correlate to optical data and classical electrodynamics calculations from the exact same particles. EELS mapping is thus demonstrated to be an invaluable technique for elucidating complex and overlapping plasmon modes.

  17. Accuracy of photon correlation measurements on nonergodic samples.

    PubMed

    Schätzel, K

    1993-07-20

    Three different photon correlation methods are used to obtain the dynamic structure factor of nonergodic samples, such as glasses or gels. These methods are compared in terms of their statistical accuracies and applicabilities. The scheme suggested by Pusey and van Megen [Phys. A 157, 705 (1989)] appears to be the most efficient one, but it is restricted to Gaussian light with a completely frozen nonergodic component. PMID:20830020

  18. Reduction of Gun Erosion and Correlation of Gun Erosion Measurements

    NASA Technical Reports Server (NTRS)

    Bogdanoff, Dave; Wercinski, Paul (Technical Monitor)

    1997-01-01

    Gun barrel erosion is serious problem with two-stage light gas guns. Excessive barrel erosion can lead to poor or failed launches and frequent barrel changes, with the corresponding down time. Also, excessive barrel erosion can limit the maximum velocity obtainable by loading down the hydrogen working gas with eroded barrel material. Guided by a CFD code, the operating conditions of the Ames 0.5-inch gun were modified to reduce barrel erosion. The changes implemented included: (1) reduction in the piston mass, powder mass and hydrogen fill pressure; and (2) reduction in pump tube volume, while maintaining hydrogen mass. The latter change was found, in particular, to greatly reduce barrel erosion. For muzzle velocity ranges of 6.1 - 6.9 km/sec, the barrel erosion was reduced by a factor of 10. Even for the higher muzzle velocity range of 7.0 - 8.2 km/sec, the barrel erosion was reduced by a factor of 4. Gun erosion data from the Ames 0.5-inch, 1.0-inch, and 1.5-inch guns operated over a wide variety of launch conditions was examined and it was found that this data could be correlated using four different parameters: normalized powder charge energy, normalized hydrogen energy density, normalized pump tube volume and barrel diameter. The development of the correlation and the steps used to collapse the experimental data are presented. Over a certain parameter range in the correlation developed, the barrel erosion per shot is found to increase very rapidly. The correlation should prove useful in the selection of gun operating conditions and the design of new guns. Representative shapes of eroded gun barrels are also presented.

  19. Effect of Crystal Defects on Minority Carrier Diffusion Length in 6H SiC Measured Using the Electron Beam Induced Current Method

    NASA Technical Reports Server (NTRS)

    Tabib-Azar, Massood

    1997-01-01

    We report values of minority carrier diffusion length in n-type 6H SiC measured using a planar Electron Beam Induced Current (EBIC) method. Values of hole diffusion length in defect free regions of n-type 6H SiC, with a doping concentration of 1.7El7 1/cu cm, ranged from 1.46 microns to 0.68 microns. We next introduce a novel variation of the planar method used above. This 'planar mapping' technique measured diffusion length along a linescan creating a map of diffusion length versus position. This map is then overlaid onto the EBIC image of the corresponding linescan, allowing direct visualization of the effect of defects on minority carrier diffusion length. Measurements of the above n-type 6H SiC resulted in values of hole diffusion length ranging from 1.2 micron in defect free regions to below 0.1 gm at the center of large defects. In addition, measurements on p-type 6H SiC resulted in electron diffusion lengths ranging from 1.42 micron to 0.8 micron.

  20. On using the levelling of the free surface of a Newtonian fluid to measure viscosity and Navier slip length

    PubMed Central

    Gilormini, P.; Teyssèdre, H.

    2013-01-01

    Measuring the relaxation time involved in the levelling of a free surface of a Newtonian fluid laid on a substrate can give access to material parameters. It is shown here how most favourable pattern geometries of the free surface and film thicknesses can be defined for the measures of viscosity and Navier slip length at the fluid–solid interface, respectively. Moreover, we put special emphasis on the conditions required to avoid shear thinning by controlling the maximum shear rate. For initially sinusoidal patterns with infinitesimal amplitudes, an analytical solution including slip at the fluid–solid interface is used, and numerical simulations based on the natural element method allow one to discuss the effect of finite amplitudes. This leads to the definition of a relevance domain for the analytical solution that avoids the need for numerical simulations in practical applications. It is also shown how these results can be applied to crenelated profiles, where Fourier series expansion can be used, but with caution. PMID:24353474

  1. Noninvasive Online Measurement of Genome Lengths of Mammalian Tissues in Bulk by 14 MeV Neutron Atometry

    NASA Astrophysics Data System (ADS)

    Maglich, Bogdan; Radovic, Anna; Druey, Christian

    2012-10-01

    Genome length, L=, no. of DNA nucleotide base pairs in cell of bovine (b) and porcine (p) tissues, closest to human genome, were hitherto measured by genomic sequencing Lb=3, Lp=2.7 Giga base pairs [1,2] (Gbp) errors not given. - We report measurements of Lb/Lp and Lb, Lp without sequencing by atometry [3,4]. No. of O and C atoms, N, in nucleotide molecules, was obtained from prompt γ rate, G, emitted in inel. scatt. 14 MeV neutrons, with nuclei of C, O, in nucleotide molecule. Since G prop. N, Lb/Lp=Gb/Gp. p and b meat was irradiated for 30'. From msd G we obtained Lb /Lp=1.28±0.02 16% greater than [1,2]. We got absolute Lb=1.65/f, Lp=1.28/f Gbp, 0.3

  2. Length Dependence of Tunneling Current Through Single Phenylene Oligomers Measured by Scanning Tunneling Microscopy at Low Temperature

    NASA Astrophysics Data System (ADS)

    Wakamatsu, Satoshi; Fujii, Shintaro; Akiba, Uichi; Fujihira, Masamichi

    2006-04-01

    The length dependence of tunneling current through single phenylene oligomers, i.e., benzenemethanethiol, 4-biphenylmethanethiol and [1,1':4',1''-terphenyl]-4-methanethiol, was determined experimentally by scanning tunneling microscopy (STM). The single phenylene oligomers were isolated in a self-assembled monolayer (SAM) matrix of a disulfide with two spherical bicyclo[2.2.2]octane moieties on Au(111). The STM measurement was conducted at a low temperature to prevent the thermal motions of the isolated molecules that occur at room temperature. The isolated single molecules inserted in the SAM matrix were observed as protrusions in an STM topography using a constant-current mode owing to their higher tunneling ability. The decay constant, β, of the tunneling current through single phenylene oligomers was estimated from the STM heights of the protrusions corresponding to the single phenylene oligomers using a bilayer tunnel junction model. The value of β for tunneling current through single phenylene oligomers was 5.5 ± 0.2 nm-1. In a constant-height mode, we measured the conductance of the isolated single molecules. We estimated an averaged single-molecular conductance of the isolated molecules of a biphenyl derivative to be ca. 2 nS. Here, one side of each isolated molecule was bound via an Au-S bond and the other phenyl end was physically in contact with an Au STM tip.

  3. Safety, Feasibility, and Reliability of the Maximal Step Length, Gait Speed, and Chair Test Measured by Seniors Themselves: The Senior Step Study.

    PubMed

    Bongers, Kim T; Schoon, Yvonne; Graauwmans, Maartje J; Hoogsteen-Ossewaarde, Marlies E; Olde Rikkert, Marcel G M

    2015-07-01

    Self-management of mobility and fall risk might be possible if older adults could use a simple and safe self-test to measure their own mobility, balance, and fall risk at home. The aim of this study was to determine the safety, feasibility, and intraindividual reliability of the maximal step length (MSL), gait speed (GS), and chair test (CT) as potential self-tests for assessing mobility and fall risk. Fifty-six community-dwelling older adults performed MSL, GS, and CT at home once a week during a four-week period, wherein the feasibility, test-retest reliability, coefficients of variation, and linear mixed models with random effects of these three self-tests were determined. Forty-nine subjects (mean age 76.1 years [SD: 4.0], 19 females [42%]) completed the study without adverse effects. Compared with the other self-tests, MSL gave the most often (77.6%) valid measurement results and had the best intraclass correlation coefficients (0.95 [95% confidence interval: 0.91-0.97]). MSL and GS gave no significant training effect, whereas CT did show a significant training effect (p < .01). Community-dwelling older adults can perform MSL safely, correctly, and reliably, and GS safely and reliably. Further research is needed to study the responsiveness and beneficial effects of these self-tests on self-management of mobility and fall risk. PMID:25342646

  4. Accounting for Correlations across Measures of Perspective Taking.

    ERIC Educational Resources Information Center

    Rose, Samuel P.

    This study examined the development of cognitive perspective taking skills and the lack of consistency across perspective taking measures in earlier studies. Four perspective taking measures were administered to 56 children between 4 and 10 years of age under two testing conditions. The high structure condition included multiple presentation of…

  5. Rapid, Accurate, and Non-Invasive Measurement of Zebrafish Axial Length and Other Eye Dimensions Using SD-OCT Allows Longitudinal Analysis of Myopia and Emmetropization

    PubMed Central

    Collery, Ross F.; Veth, Kerry N.; Dubis, Adam M.; Carroll, Joseph; Link, Brian A.

    2014-01-01

    Refractive errors in vision can be caused by aberrant axial length of the eye, irregular corneal shape, or lens abnormalities. Causes of eye length overgrowth include multiple genetic loci, and visual parameters. We evaluate zebrafish as a potential animal model for studies of the genetic, cellular, and signaling basis of emmetropization and myopia. Axial length and other eye dimensions of zebrafish were measured using spectral domain-optical coherence tomography (SD-OCT). We used ocular lens and body metrics to normalize and compare eye size and relative refractive error (difference between observed retinal radial length and controls) in wild-type and lrp2 zebrafish. Zebrafish were dark-reared to assess effects of visual deprivation on eye size. Two relative measurements, ocular axial length to body length and axial length to lens diameter, were found to accurately normalize comparisons of eye sizes between different sized fish (R2 = 0.9548, R2 = 0.9921). Ray-traced focal lengths of wild-type zebrafish lenses were equal to their retinal radii, while lrp2 eyes had longer retinal radii than focal lengths. Both genetic mutation (lrp2) and environmental manipulation (dark-rearing) caused elongated eye axes. lrp2 mutants had relative refractive errors of −0.327 compared to wild-types, and dark-reared wild-type fish had relative refractive errors of −0.132 compared to light-reared siblings. Therefore, zebrafish eye anatomy (axial length, lens radius, retinal radius) can be rapidly and accurately measured by SD-OCT, facilitating longitudinal studies of regulated eye growth and emmetropization. Specifically, genes homologous to human myopia candidates may be modified, inactivated or overexpressed in zebrafish, and myopia-sensitizing conditions used to probe gene-environment interactions. Our studies provide foundation for such investigations into genetic contributions that control eye size and impact refractive errors. PMID:25334040

  6. Predetermination of root canal lengths in molar teeth: A comparison between radiovisiography and two-dimensional and three-dimensional measurements using cone-beam computed tomography

    PubMed Central

    Dhingra, Annil; Dayal, Charu; Singh, Amteshwar; Bhardwaj, Neetika

    2015-01-01

    Introduction: Obtaining a correct working length is critical to the success of endodontic therapy. The aim of this clinical study was to compare the effect of working length determination using radiovisiography (RVG) and two-dimensional (2D) and three-dimensional (3D) measurements using cone-beam computed tomography (CBCT). Materials and Methods: Thirty mandibular teeth were taken and three groups of 10 each were made. Teeth with previous endodontic treatments, metal restorations, resorptions, incomplete apex formations, and multiple visible foramina were excluded. The root canal length was determined using RVG, CBCT measurement method 2D, and CBCT measurement method 3D. The difference between CBCT measurements, RVG, and the actual canal length were compared to evaluate the accuracy of each method. Results: No significant statistically difference was seen with 3D measurements and actual measurements. Measurements with RVG were better than CBCT 2D. Conclusion: Under experimental conditions, CBCT 3D measurements are accurate than RVG and CBCT 2D in the determination of root canal length. PMID:26752880

  7. Column Path Length Measurements Using a Multi-Frequency, Intensity-Modulated Continuous-Wave (IM-CW) Laser Absorption Spectrometer

    NASA Astrophysics Data System (ADS)

    Harrison, F. W.; Lin, B.; Browell, E. V.; Dobler, J.; McGregor, D.; Kooi, S. A.; Collins, J. E.

    2012-12-01

    Accurate understanding of carbon balance in the environment is critical to projections of the future evolution of the Earth's climate. As a result, the NRC Decadal Survey (DS) of Earth Science and Applications from Space identified Active Sensing of CO2 Emissions over Nights, Days, and Seasons (ASCENDS) as a mid-term (Tier II) mission. The active space remote measurement of the column CO2 mixing ratio (XCO2) for the ASCENDS mission requires the simultaneous measurement of the CO2 and O2 number density and the column path length over which they are measured in order to derive the average XCO2 column. This paper presents methods for measuring the path lengths of the CO2 and O2 measurements that are inherent to the Multi-Functional Fiber Laser Lidar (MFLL), a laser absorption spectrometer (LAS) system under development for the ASCENDS mission. The MFLL is a multi-frequency intensity-modulated continuous-wave (IM-CW) LAS operating near 1.57 and 1.26 μm that uses a range-encoded modulation technique to minimize bias from thin clouds in the CO2 and O2 column measurements while simultaneously measuring the path length to the surface and to intervening cloud layers. This paper discusses the latest MFLL ground and flight test results. During these tests, range-encoded modulation techniques were demonstrated for path length measurements and the MFLL remote CO2 column measurements were evaluated against in situ CO2 measurements. This paper describes the encoding techniques employed, presents an approach for obtaining column path length measurements during CO2 retrievals, and presents the accuracy and precision of the technique. Measurement of path length meeting ASCENDS requirements of approximately 2-m precision were obtained in ground testing and demonstrated during flights over Railroad Valley, NV.

  8. Expression of Telomeres in Astrocytoma WHO Grade 2 to 4: TERRA Level Correlates with Telomere Length, Telomerase Activity, and Advanced Clinical Grade12

    PubMed Central

    Sampl, Sandra; Pramhas, Sibylle; Stern, Christian; Preusser, Matthias; Marosi, Christine; Holzmann, Klaus

    2012-01-01

    Cancer cells bypass replicative senescence, the major barrier to tumor progression, by using telomerase or alternative lengthening of telomeres (ALT) as telomere maintenance mechanisms (TMMs). Correlation between ALT and patient survival was demonstrated for high-grade astrocytomas. Transcription from subtelomeres produces telomeric repeat-containing RNA (TERRA), a natural inhibitor of telomerase activity (TA). This led us to evaluate correlations of TERRA and TMM with tumor grade and outcome in astrocytoma patients. SYBR Green real-time reverse transcription-polymerase chain reaction assays for quantitation of total and chromosome 2p and 18p specific TERRA levels were developed. Tumor samples from 46 patients with astrocytoma grade 2 to 4, tissue controls, and cell lines were assessed. TMMs were evaluated by measuring TA and by detecting long telomeres due to ALT. In glioblastoma multiforme (GBM) grade 4, total TERRA levels were similar to cell lines but 14-, 31-, and 313-fold lower compared with grade 3, grade 2, and nonmalignant tissue, respectively. Total TERRA levels differed from chromosomal levels. Low 2p TERRA levels correlated with dense promoter methylation of subtelomeric CpG islands, indicating that TERRA expression in gliomas may be chromosome specific and epigenetically regulated. Total TERRA levels correlated with diagnosis, with low or absent TA and the presence of ALT, and were tentatively associated with favorable patient prognosis in our cohort (P = .06). TA and short telomeres identified a subset of GBM with a median survival of only 14.8 months. TERRA and TA may be prognostic in astrocytic tumors. PMID:22348177

  9. Correlation measurements of light transmittance in polymer dispersed liquid crystals

    NASA Astrophysics Data System (ADS)

    Maksimyak, P. P.; Nehrych, A. L.

    2015-11-01

    The methods of correlation optics are for the first time applied to study structure of liquid crystal (LC) - polymer (P) composites at various concentrations of LC and P. Their phase correlation function (PCF) was obtained considering LC-P composite as a random phase screen. The amplitude of PCF contains information about number of LC domains and structure of LC director inside of them, while a half-width of this function is connected with a size of these domains. We studied unpowered and powered composite layers with a thickness of 5 μm. As liquid crystal and polymer were used nematic LC E7 from Merck and photopolymer composition NOA65 from Norland. Concentration of polymer φP was varied in a range 10-55 vol. %. In good agreement with previous studies by SEM technique we detected monotone decrease of LC domains with concentration of polymer. With application of electric field, amplitude of PCF behaves differently for the samples with different polymer content. For the samples with φP>35 vol. % (samples having morphology of polymer dispersed LC), this dependence is monotonic. In turn, if φP<35 vol. % (samples with polymer network LC morphology), the amplitude of PCF non-monotonically depends on the applied voltage going through a maximum. The latter fact is explained by transformation of orientational defects of LC phase with the applied voltage.

  10. Feasibility of repeated self-measurements of maximum step length and gait speed by community-dwelling older persons

    PubMed Central

    Bongers, Kim T J; Schoon, Yvonne; Olde Rikkert, Marcel G M

    2016-01-01

    Objectives Self-management of mobility and fall risk can be important in fall prevention; however, it remains unstudied. Therefore, the current study assessed whether community-dwelling older persons were able to repeatedly self-assess maximum step length (MSL) and gait speed (GS) in their own home for a 6-month period, how these tests changed during this period and if these changes were related to falling. Design This is a prospective study. Setting This study was conducted at home. Participants A total of 56 community-dwelling older adults (24 women (43%), mean age 76.2 (SD 3.9) years) entered the study; of which, 45 completed the study. Methods Participants performed MSL and GS once a week in their own home during a 6-month period. Primary and secondary outcomes Repeated MSL and GS measurements were the primary outcomes. Falls, self-management and mobility were the secondary outcomes. Results Self-assessment of MSL and GS by older persons is feasible. Compliance of repeatedly self-measuring MSL and GS was good; the median number of weekly measurements was 23.0 (88%) and 21.0 (81%) for MSL and GS, respectively. Drop-outs showed less self-management abilities compared to the participants who completed the study (p=0.049). Linear mixed models showed a small significant improvement in MSL and GS over time (p<0.001), without an influence on falling. Conclusions Most community-dwelling older persons are able and willing to repeatedly assess their MSL and GS. Self-managing mobility and fall risk did not increase fall occurrence. The fact that older persons can be actively involved in their own healthcare is clinically relevant. Further studies are needed to examine the (cost-)effectiveness of self-management in fall prevention interventions. PMID:27496235

  11. Role of Weak Measurements on States Ordering and Monogamy of Quantum Correlation

    NASA Astrophysics Data System (ADS)

    Hu, Ming-Liang; Fan, Heng; Tian, Dong-Ping

    2015-01-01

    The information-theoretic definition of quantum correlation, e.g., quantum discord, is measurement dependent. By considering the more general quantum measurements, weak measurements, which include the projective measurement as a limiting case, we show that while weak measurements can enable one to capture more quantumness of correlation in a state, it can also induce other counterintuitive quantum effects. Specifically, we show that the general measurements with different strengths can impose different orderings for quantum correlations of some states. It can also modify the monogamous character for certain classes of states as well which may diminish the usefulness of quantum correlation as a resource in some protocols. In this sense, we say that the weak measurements play a dual role in defining quantum correlation.

  12. Measurements of the microwave spectrum, Re-H bond length, and Re quadrupole coupling for HRe(CO)5

    NASA Astrophysics Data System (ADS)

    Kukolich, Stephen G.; Sickafoose, Shane M.

    1993-11-01

    Rotational transition frequencies for rhenium pentacarbonyl hydride were measured in the 4-10 GHz range using a Flygare-Balle type microwave spectrometer. The rotational constants and Re nuclear quadrupole coupling constants for the four isotopomers, (1) H187Re(CO)5, (2) H185Re(CO)5, (3) D187Re(CO)5, and (4) D185Re(CO)5, were obtained from the spectra. For the most common isotopomer, B(1)=818.5464(2) MHz and eq Q(187Re)=-900.13(3) MHz. The Re-H bond length (r0) determined by fitting the rotational constants is 1.80(1) Å. Although the Re atom is located at a site of near-octahedral symmetry, the quadrupole coupling is large due to the large Re nuclear moments. A 2.7% increase in Re quadrupole coupling was observed for D-substituted isotopomers, giving a rather large isotope effect on the quadrupole coupling. The Cax-Re-Ceq angle is 96(1)°, when all Re-C-O angles are constrained to 180°.

  13. Efficiency of static and computer adaptive short forms compared to full-length measures of depressive symptoms

    PubMed Central

    Choi, Seung W.; Reise, Steven P.; Pilkonis, Paul A.; Hays, Ron D.; Cella, David

    2010-01-01

    Purpose Short-form patient-reported outcome measures are popular because they minimize patient burden. We assessed the efficiency of static short forms and computer adaptive testing (CAT) using data from the Patient-Reported Outcomes Measurement Information System (PROMIS) project. Methods We evaluated the 28-item PROMIS depressive symptoms bank. We used post hoc simulations based on the PROMIS calibration sample to compare several short-form selection strategies and the PROMIS CAT to the total item bank score. Results Compared with full-bank scores, all short forms and CAT produced highly correlated scores, but CAT outperformed each static short form in almost all criteria. However, short-form selection strategies performed only marginally worse than CAT. The performance gap observed in static forms was reduced by using a two-stage branching test format. Conclusions Using several polytomous items in a calibrated unidimensional bank to measure depressive symptoms yielded a CAT that provided marginally superior efficiency compared to static short forms. The efficiency of a two-stage semi-adaptive testing strategy was so close to CAT that it warrants further consideration and study. PMID:19941077

  14. Weighted network analysis of high-frequency cross-correlation measures.

    PubMed

    Iori, Giulia; Precup, Ovidiu V

    2007-03-01

    In this paper we implement a Fourier method to estimate high-frequency correlation matrices from small data sets. The Fourier estimates are shown to be considerably less noisy than the standard Pearson correlation measures and thus capable of detecting subtle changes in correlation matrices with just a month of data. The evolution of correlation at different time scales is analyzed from the full correlation matrix and its minimum spanning tree representation. The analysis is performed by implementing measures from the theory of random weighted networks. PMID:17500762

  15. Weighted network analysis of high-frequency cross-correlation measures

    NASA Astrophysics Data System (ADS)

    Iori, Giulia; Precup, Ovidiu V.

    2007-03-01

    In this paper we implement a Fourier method to estimate high-frequency correlation matrices from small data sets. The Fourier estimates are shown to be considerably less noisy than the standard Pearson correlation measures and thus capable of detecting subtle changes in correlation matrices with just a month of data. The evolution of correlation at different time scales is analyzed from the full correlation matrix and its minimum spanning tree representation. The analysis is performed by implementing measures from the theory of random weighted networks.

  16. Correlation between precision gravity and subsidence measurements at Cerro Prieto

    SciTech Connect

    Zelwer, R.; Grannell, R.B.

    1982-10-01

    Precision gravity measurements were made in the region of the Cerro Prieto geothermal field at yearly intervals from 1977 to 1981 to assess the feasibility of using gravity to determine subsurface reservoir changes with time. The extent of mass recharge in response to the continued production of fluids from this field was studied. Changes in gravity and ground elevation were observed throughout the region for the period of observation. Results indicate that the largest changes observed were the result of the Magnitude 6.1 (Caltech) Victoria earthquake of 8 June 1980. The epicenter of this earthquake was located 25 km southeast of the field on the Cerro Prieto Fault, which bounds the field on the southwest. Subsidence of up to 55 cm was measured east of the power plant, in the region between the northern end of the Cerro Prieto Fault and the southern end of the Imperial Fault. This area has been postulated to be the site of an active spreading center or pull-apart basin, and has been characterized by a high level of seismic activity during the last 10 years. Minor subsidence and small related gravity changes for the period preceeding the Victoria earthquake suggest that in spite of large fluid production rates, the reservoir is being almost completely recharged and that a measurable increase in subsurface density may be taking place. The results of measurements of horizontal ground motions made in this area are discussed in relation to the gravity and subsidence observations.

  17. Measurement of N-Type 6H SiC Minority-Carrier Diffusion Lengths by Electron Bombardment of Schottky Barriers

    NASA Technical Reports Server (NTRS)

    Hubbard, S. M.; Tabib-Azar, M.; Balley, S.; Rybickid, G.; Neudeck, P.; Raffaelle, R.

    2004-01-01

    Minority-Carrier diffusion lengths of n-type 6H-SiC were measured using the electron-beam induced current (EBIC) technique. Experimental values of primary beam current, EBIC, and beam voltage were obtained for a variety of SIC samples. This data was used to calculate experimental diode efficiency vs. beam voltage curves. These curves were fit to theoretically calculated efficiency curves, and the diffusion length and metal layer thickness were extracted. The hole diffusion length in n-6H SiC ranged from 0.93 +/- 0.15 microns.

  18. TURBULENT DYNAMICS IN SOLAR FLARE SHEET STRUCTURES MEASURED WITH LOCAL CORRELATION TRACKING

    SciTech Connect

    McKenzie, D. E.

    2013-03-20

    High-resolution observations of the Sun's corona in extreme ultraviolet and soft X-rays have revealed a new world of complexity in the sheet-like structures connecting coronal mass ejections (CMEs) to the post-eruption flare arcades. This article presents initial findings from an exploration of dynamic flows in two flares observed with Hinode/XRT and SDO/AIA. The flows are observed in the hot ({approx}> 10 MK) plasma above the post-eruption arcades and measured with local correlation tracking. The observations demonstrate significant shears in velocity, giving the appearance of vortices and stagnations. Plasma diagnostics indicate that the plasma {beta} exceeds unity in at least one of the studied events, suggesting that the coronal magnetic fields may be significantly affected by the turbulent flows. Although reconnection models of eruptive flares tend to predict a macroscopic current sheet in the region between the CME and the flare arcade, it is not yet clear whether the observed sheet-like structures are identifiable as the current sheets or 'thermal halos' surrounding the current sheets. Regardless, the relationship between the turbulent motions and the embedded magnetic field is likely to be complicated, involving dynamic fluid processes that produce small length scales in the current sheet. Such processes may be crucial for triggering, accelerating, and/or prolonging reconnection in the corona.

  19. Cloud Turbulence Correlation Functions and Power Spectra Measured using a Gyroklystron-Powered 94 GHz Radar

    NASA Astrophysics Data System (ADS)

    Fliflet, Arne; Manheimer, Wallace; Linde, George; Cheung, Winjoy; Ngo, Mai; Gregershansen, Vilhelm; Danly, Bruce; St. Germain, Karen

    2003-10-01

    The Naval Research Laboratory (NRL) has recently developed a high power 94 GHz radar called WARLOC. This radar has unique advantages for cloud research stemming from the fact that the return from clouds scales inversely as the fourth power of the wavelength. Clouds are largely invisible to conventional radars and opaque to lidars, whereas millimeter-wave radars produce strong signals from cloud water droplets. Thus W-Band radars can be used to sense the internal structure of clouds. The WARLOC transmitter has about three orders-of-magnitude more average power than the W-Band radars used in previous cloud studies and greatly improved resolution and scanning capability. Here we report initial results on cloud studies. The new capabilities of WARLOC have allowed us to produce high-resolution images of the internal structure of clouds. Regions many square kilometers in area can be scanned with 15 m resolution in about a minute even through intervening cloud layers. The scanned cloud reflectivity yields two-dimensional cloud turbulence correlation functions and power spectra directly from spatial measurements for the first time, and with higher resolution than previously possible. We find that in the inertial range, the Kolmogorov spectral index (-5/3) agrees reasonably well with the data, but the assumption of isotropy does not. Interestingly, in two clouds studied, at longer scale lengths, the fluctuations appear to be wavelike in the vertical direction, but not in the horizontal direction.

  20. Dimension of quantum phase space measured by photon correlations

    NASA Astrophysics Data System (ADS)

    Leuchs, Gerd; Glauber, Roy J.; Schleich, Wolfgang P.

    2015-06-01

    We show that the different values 1, 2 and 3 of the normalized second-order correlation function {g}(2)(0) corresponding to a coherent state, a thermal state and a highly squeezed vacuum originate from the different dimensionality of these states in phase space. In particular, we derive an exact expression for {g}(2)(0) in terms of the ratio of the moments of the classical energy evaluated with the Wigner function of the quantum state of interest and corrections proportional to the reciprocal of powers of the average number of photons. In this way we establish a direct link between {g}(2)(0) and the shape of the state in phase space. Moreover, we illuminate this connection by demonstrating that in the semi-classical limit the familiar photon statistics of a thermal state arise from an area in phase space weighted by a two-dimensional Gaussian, whereas those of a highly squeezed state are governed by a line-integral of a one-dimensional Gaussian. We dedicate this article to Margarita and Vladimir Man’ko on the occasion of their birthdays. The topic of our contribution is deeply rooted in and motivated by their love for non-classical light, quantum mechanical phase space distribution functions and orthogonal polynomials. Indeed, through their articles, talks and most importantly by many stimulating discussions and intensive collaborations with us they have contributed much to our understanding of physics. Happy birthday to you both!