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Sample records for cric ancillary study

  1. Aortic PWV in Chronic Kidney Disease: A CRIC Ancillary Study

    PubMed Central

    Townsend, Raymond R.; Wimmer, Neil J.; Chirinos, Julio A.; Parsa, Afshin; Weir, Matthew; Perumal, Kalyani; Lash, James P.; Chen, Jing; Steigerwalt, Susan P.; Flack, John; Go, Alan S.; Rafey, Mohammed; Rahman, Mahboob; Sheridan, Angela; Gadegbeku, Crystal A.; Robinson, Nancy A.; Joffe, Marshall

    2009-01-01

    Background Aortic PWV is a measure of arterial stiffness and has proved useful in predicting cardiovascular morbidity and mortality in several populations of patients, including the healthy elderly, hypertensives and those with end stage renal disease receiving hemodialysis. Little data exist characterizing aortic stiffness in patients with chronic kidney disease who are not receiving dialysis, and in particular the effect of reduced kidney function on aortic PWV. Methods We performed measurements of aortic PWV in a cross-sectional cohort of participants enrolled in the Chronic Renal Insufficiency Cohort (CRIC) study to determine factors which predict increased aortic PWV in chronic kidney disease. Results PWV measurements were obtained in 2564 participants. The tertiles of aortic PWV (adjusted for waist circumference) were < 7.7 m/sec, 7.7–10.2 m/sec and > 10.2 m/sec with an overall mean (± S.D.) value of 9.48 ± 3.03 m/sec [95% CI = 9.35–9.61 m/sec]. Multivariable regression identified significant independent positive associations of age, blood glucose concentrations, race, waist circumference, mean arterial blood pressure, gender, and presence of diabetes with aortic PWV and a significant negative association with the level of kidney function. Conclusions The large size of this unique cohort, and the targeted enrollment of chronic kidney disease participants provides an ideal situation to study the role of reduced kidney function as a determinant of arterial stiffness. Arterial stiffness may be a significant component of the enhanced cardiovascular risk associated with kidney failure. PMID:20019670

  2. CKD in Hispanics: Baseline Characteristics From the CRIC (Chronic Renal Insufficiency Cohort) and Hispanic-CRIC Studies

    PubMed Central

    Fischer, Michael J.; Go, Alan; Lora, Claudia M.; Ackerson, Lynn; Cohan, Janet; Kusek, John; Mercado, Alejandro; Ojo, Akinlolu; Ricardo, Ana C.; Rosen, Leigh; Tao, Kelvin; Xie, Dawei; Feldman, Harold; Lash, James P.

    2012-01-01

    Background Little is known regarding chronic kidney disease (CKD) in Hispanics. We compared baseline characteristics of Hispanic participants in the Chronic Renal Insufficiency Cohort (CRIC) and Hispanic-CRIC (H-CRIC) Studies with non-Hispanic CRIC participants. Study Design Cross-sectional analysis Setting and Participants Participants were aged 21–74 years with CKD using age-based glomerular filtration rate (eGFR) at enrollment into the CRIC/H-CRIC Studies. H-CRIC included Hispanics recruited at the University of Illinois from 2005–2008 while CRIC included Hispanics and non-Hispanics recruited at seven clinical centers from 2003–2007. Factor Race/ethnicity Outcomes Blood pressure, angiotensin-converting enzyme (ACE) inhibitor/angiotensin receptor blocker (ARB) use, CKD-associated complications Measurements Demographic characteristics, laboratory data, blood pressure, and medications were assessed using standard techniques and protocols Results Among H-CRIC/ CRIC participants, 497 were Hispanic, 1650 non-Hispanic Black, and 1638 non-Hispanic White. Low income and educational attainment were nearly twice as prevalent in Hispanics compared with non-Hispanics (p<0.01). Hispanics had self-reported diabetes (67%) more frequently than non-Hispanic Blacks (51%) and Whites (40%) (p<0.01). Blood pressure > 130/80 mmHg was more common in Hispanics (62%) compared with Blacks (57%) and Whites (35%) (p<0.05), and abnormalities in hematologic, metabolic, and bone metabolism parameters were more prevalent in Hispanics (p<0.05), even after stratifying by entry eGFR. Hispanics had the lowest receipt of ACE inhibitor/ARB among high-risk subgroups, including participants with diabetes, proteinuria, and blood pressure > 130/80 mmHg. Mean eGFR (ml/min/m2) was lower in Hispanics (39.6) than in Blacks (43.7) and Whites (46.2), while median proteinuria was higher in Hispanics (0.72 g/d) than in Blacks (0.24 g/d) and Whites (0.12 g/d) (p<0.01). Limitations Generalizability; observed

  3. The Chronic Renal Insufficiency Cohort (CRIC) Study: Design and Methods.

    PubMed

    Feldman, Harold I; Appel, Lawrence J; Chertow, Glenn M; Cifelli, Denise; Cizman, Borut; Daugirdas, John; Fink, Jeffrey C; Franklin-Becker, Eunice D; Go, Alan S; Hamm, L Lee; He, Jiang; Hostetter, Tom; Hsu, Chi-Yuan; Jamerson, Kenneth; Joffe, Marshall; Kusek, John W; Landis, J Richard; Lash, James P; Miller, Edgar R; Mohler, Emile R; Muntner, Paul; Ojo, Akinlolu O; Rahman, Mahboob; Townsend, Raymond R; Wright, Jackson T

    2003-07-01

    Insights into end-stage renal disease have emerged from many investigations but less is known about the epidemiology of chronic renal insufficiency (CRI) and its relationship to cardiovascular disease (CVD). The Chronic Renal Insufficiency Cohort (CRIC) Study was established to examine risk factors for progression of CRI and CVD among CRI patients and develop models to identify high-risk subgroups, informing future treatment trials, and increasing application of preventive therapies. CRIC will enroll approximately 3000 individuals at seven sites and follow participants for up to 5 yr. CRIC will include a racially and ethnically diverse group of adults aged 21 to 74 yr with a broad spectrum of renal disease severity, half of whom have diagnosed diabetes mellitus. CRIC will exclude subjects with polycystic kidney disease and those on active immunosuppression for glomerulonephritis. Subjects will undergo extensive clinical evaluation at baseline and at annual clinic visits and via telephone at 6 mo intervals. Data on quality of life, dietary assessment, physical activity, health behaviors, depression, cognitive function, health care resource utilization, as well as blood and urine specimens will be collected annually. (125)I-iothalamate clearances and CVD evaluations including a 12-lead surface electrocardiogram, an echocardiogram, and coronary electron beam or spiral CT will be performed serially. Analyses planned in CRIC will provide important information on potential risk factors for progressive CRI and CVD. Insights from CRIC should lead to the formulation of hypotheses regarding therapy that will serve as the basis for targeted interventional trials focused on reducing the burden of CRI and CVD. PMID:12819321

  4. Estimating GFR Among Participants in the Chronic Renal Insufficiency Cohort (CRIC) Study

    PubMed Central

    Anderson, Amanda Hyre; Yang, Wei; Hsu, Chi-yuan; Joffe, Marshall M.; Leonard, Mary B.; Xie, Dawei; Chen, Jing; Greene, Tom; Jaar, Bernard G.; Kao, Patricia; Kusek, John W.; Landis, J. Richard; Lash, James P.; Townsend, Raymond R.; Weir, Matthew R.; Feldman, Harold I.

    2012-01-01

    Background Glomerular filtration rate (GFR) is considered the best measure of kidney function, but repeated assessment is not feasible in most research studies. Study Design Cross-sectional study of 1,433 participants from the Chronic Renal Insufficiency Cohort (CRIC) Study (i.e., the GFR subcohort) to derive an internal GFR estimating equation using a split sample approach. Setting & Participants Adults from 7 US metropolitan areas with mild to moderate chronic kidney disease; 48% had diabetes and 37% were black. Index Test CRIC GFR estimating equation Reference Test or Outcome Urinary 125I-iothalamate clearance testing (measured GFR) Other Measurements Laboratory measures including serum creatinine and cystatin C, and anthropometrics Results In the validation dataset, the model that included serum creatinine, serum cystatin C, age, gender, and race was the most parsimonious and similarly predictive of mGFR compared to a model additionally including bioelectrical impedance analysis phase angle, CRIC clinical center, and 24-hour urinary creatinine excretion. Specifically, the root mean square errors for the separate model were 0.207 vs. 0.202, respectively. The performance of the CRIC GFR estimating equation was most accurate among the subgroups of younger participants, men, non-blacks, non-Hispanics, those without diabetes, those with body mass index <30 kg/m2, those with higher 24-hour urine creatinine excretion, those with lower levels of high-sensitivity C-reactive protein, and those with higher mGFR. Limitations Urinary clearance of 125I-iothalamate is an imperfect measure of true GFR; cystatin C is not standardized to certified reference material; lack of external validation; small sample sizes limit analyses of subgroup-specific predictors. Conclusions The CRIC GFR estimating equation predicts measured GFR accurately in the CRIC cohort using serum creatinine and cystatin C, age, gender, and race. Its performance was best among younger and healthier

  5. Factors Associated With Depressive Symptoms and Use of Antidepressant Medications Among Participants in the Chronic Renal Insufficiency Cohort (CRIC) and Hispanic-CRIC Studies

    PubMed Central

    Fischer, Michael J.; Xie, Dawei; Jordan, Neil; Kop, Willem J.; Krousel-Wood, Marie; Tamura, Manjula Kurella; Kusek, John W.; Ford, Virginia; Rosen, Leigh K.; Strauss, Louise; Teal, Valerie L.; Yaffe, Kristine; Powe, Neil R.; Lash, James P.

    2012-01-01

    Background Depressive symptoms are correlated with poor health outcomes in adults with chronic kidney disease (CKD). The prevalence, severity, and treatment of depressive symptoms and potential risk factors, including level of kidney function, in diverse populations with CKD have not been well studied. Study Design Cross-sectional analysis Settings and Participants Participants at enrollment into the Chronic Renal Insufficiency Cohort (CRIC) and Hispanic-CRIC (H-CRIC) Studies. CRIC enrolled Hispanics and non-Hispanics at seven centers from 2003-2007, and H-CRIC enrolled Hispanics at the University of Illinois from 2005-2008. Measurement Depressive symptoms measured by Beck Depression Inventory (BDI) Predictors Demographic and clinical factors Outcomes Elevated depressive symptoms (BDI >= 11) and antidepressant medication use Results Among 3853 participants, 28.5% had evidence of elevated depressive symptoms and 18.2% were using antidepressant medications; 30.8% of persons with elevated depressive symptoms were using antidepressants. The prevalence of elevated depressive symptoms varied by level of kidney function: 25.2% among participants with eGFR ≥ 60 ml/min/1.73m2, and 35.1% of those with eGFR < 30 ml/min/1.73m2. Lower eGFR (OR per 10 ml/min/1.73m2 decrease, 1.09; 95% CI, 1.03-1.16), Hispanic ethnicity (OR, 1.65; 95% CI, 1.12-2.45), and non-Hispanic black race (OR, 1.43; 95% CI, 1.17-1.74) were each associated with increased odds of elevated depressive symptoms after controlling for other factors. In regression analyses incorporating BDI score, while female sex was associated with a greater odds of antidepressant use, Hispanic ethnicity, non-Hispanic black race, and higher levels of urine albumin were associated with decreased odds of antidepressant use (p<0.05 for each). Limitations Absence of clinical diagnosis of depression and use of non-pharmacologic treatments Conclusions Although elevated depressive symptoms were common in individuals with CKD, use of

  6. Urinary Creatinine Excretion, Bioelectrical Impedance Analysis, and Clinical Outcomes in Patients with CKD: The CRIC Study

    PubMed Central

    Xie, Dawei; Anderson, Amanda H.; Leonard, Mary B.; Reese, Peter P.; Delafontaine, Patrice; Horwitz, Edward; Kallem, Radhakrishna; Navaneethan, Sankar; Ojo, Akinlolu; Porter, Anna C.; Sondheimer, James H.; Sweeney, H. Lee; Townsend, Raymond R.; Feldman, Harold I.

    2014-01-01

    Background and objectives Previous studies in chronic disease states have demonstrated an association between lower urinary creatinine excretion (UCr) and increased mortality, a finding presumed to reflect the effect of low muscle mass on clinical outcomes. Little is known about the relationship between UCr and other measures of body composition in terms of the ability to predict outcomes of interest. Design, setting, participants, & measurements Using data from the Chronic Renal Insufficiency Cohort (CRIC), the relationship between UCr, fat free mass (FFM) as estimated by bioelectrical impedance analysis, and (in a subpopulation) whole-body dual-energy x-ray absorptiometry assessment of appendicular lean mass were characterized. The associations of UCr and FFM with mortality and ESRD were compared using Cox proportional hazards models. Results A total of 3604 CRIC participants (91% of the full CRIC cohort) with both a baseline UCr and FFM measurement were included; of these, 232 had contemporaneous dual-energy x-ray absorptiometry measurements. Participants were recruited between July 2003 and March 2007. UCr and FFM were modestly correlated (rho=0.50; P<0.001), while FFM and appendicular lean mass were highly correlated (rho=0.91; P<0.001). Higher urinary urea nitrogen, black race, younger age, and lower serum cystatin C level were all significantly associated with higher UCr. Over a median (interquartile range) of 4.2 (3.1–5.0) years of follow-up, 336 (9.3%) participants died and 510 (14.2%) reached ESRD. Lower UCr was associated with death and ESRD even after adjustment for FFM (adjusted hazard ratio for death per 1 SD higher level of UCr, 0.63 [95% confidence interval, 0.56 to 0.72]; adjusted hazard ratio for ESRD per 1 SD higher level of UCr, 0.70 [95% confidence interval, 0.63 to 0.75]). Conclusions Among a cohort of individuals with CKD, lower UCr is associated with death and ESRD independent of FFM as assessed by bioelectrical impedance analysis. PMID

  7. Cardiovascular Disease Among Hispanics and Non-Hispanics in the Chronic Renal Insufficiency Cohort (CRIC) Study

    PubMed Central

    Ricardo, Ana C.; Fischer, Michael J.; Lora, Claudia M.; Budoff, Matthew; Keane, Martin G.; Kusek, John W.; Martinez, Monica; Nessel, Lisa; Stamos, Thomas; Ojo, Akinlolu; Rahman, Mahboob; Soliman, Elsayed Z.; Yang, Wei; Feldman, Harold I.; Go, Alan S.

    2011-01-01

    Summary Background and objectives Hispanics are the largest minority group in the United States. The leading cause of death in patients with chronic kidney disease (CKD) is cardiovascular disease (CVD), yet little is known about its prevalence among Hispanics with CKD. Design, setting, participants, & measurements We conducted cross-sectional analyses of prevalent self-reported clinical and subclinical measures of CVD among 497 Hispanics, 1638 non-Hispanic Caucasians, and 1650 non-Hispanic African Americans, aged 21 to 74 years, with mild-to-moderate CKD at enrollment in the Chronic Renal Insufficiency Cohort (CRIC) and Hispanic CRIC (HCRIC) studies. Measures of subclinical CVD included left ventricular hypertrophy (LVH), coronary artery calcification (CAC), and ankle-brachial index. Results Self-reported coronary heart disease (CHD) was lower in Hispanics compared with non-Hispanic Caucasians (18% versus 23%, P = 0.02). Compared with non-Hispanic Caucasians, Hispanics had a lower prevalence of CAC >100 (41% versus 34%, P = 0.03) and CAC >400 (26% versus 19%, P = 0.02). However, after adjusting for sociodemographic factors, these differences were no longer significant. In adjusted analyses, Hispanics had a higher odds of LVH compared with non-Hispanic Caucasians (odds ratio 1.97, 95% confidence interval, 1.22 to 3.17, P = 0.005), and a higher odds of CAC >400 compared with non-Hispanic African Americans (odds ratio, 2.49, 95% confidence interval, 1.11 to 5.58, P = 0.03). Hispanic ethnicity was not independently associated with any other CVD measures. Conclusions Prevalent LVH was more common among Hispanics than non-Hispanic Caucasians, and elevated CAC score was more common among Hispanics than non-Hispanic African Americans. Understanding reasons for these racial/ethnic differences and their association with long-term clinical outcomes is needed. PMID:21896829

  8. Prevalence and Correlates of Mitral Annular Calcification in Adults with Chronic Kidney Disease: Results from CRIC Study

    PubMed Central

    Abd alamir, Moshrik; Radulescu, Vlad; Goyfman, Michael; Mohler, Emile R; Gao, Yan Lin; Budoff, Matthew J.

    2015-01-01

    Background Risk factors for mitral annular calcification (MAC) and cardiovascular disease (CVD) demonstrate significant overlap in the general population. The aim of this paper is to determine whether there are independent relationships between MAC and demographics, traditional and novel CVD risk factors using cardiac CT in the Chronic Renal Insufficiency Cohort (CRIC) in a cross-sectional study. Methods A sample of 2070 subjects underwent coronary calcium scanning during the CRIC study. Data were obtained for each participant at time of scan. Subjects were dichotomized into the presence and absence of MAC. Differences in baseline demographic and transitional risk factor data were evaluated across groups. Covariates used in multivariable adjustment were age, gender, BMI, HDL, LDL, lipid lowering medications, smoking status, family history of heart attack, hypertension, diabetes mellitus, phosphate, PTH, albuminuria, and calcium. Results Our study consisted of 2070 subjects, of which 331 had MAC (prevalence of 16.0%). The mean MAC score was 511.98 (SD 1368.76). Age and white race remained independently associated with presence of MAC. Decreased GFR was also a risk factor. African American and Hispanic race, as well as former smoking status were protective against MAC. In multivariable adjusted analyses, the remaining covariates were not significantly associated with MAC. Among renal covariates, elevated phosphate was significant. Conclusion In the CRIC population, presence of MAC was independently associated with age, Caucasian race, decreased GFR, and elevated phosphate. These results are suggested by mechanisms of dysregulation of inflammation, hormones, and electrolytes in subjects with renal disease. PMID:26188533

  9. DNA methylation profile associated with rapid decline in kidney function: findings from the CRIC Study

    PubMed Central

    Wing, Maria R.; Devaney, Joseph M.; Joffe, Marshall M.; Xie, Dawei; Feldman, Harold I.; Dominic, Elizabeth A.; Guzman, Nicolas J.; Ramezani, Ali; Susztak, Katalin; Herman, James G.; Cope, Leslie; Harmon, Brennan; Kwabi-Addo, Bernard; Gordish-Dressman, Heather; Go, Alan S.; He, Jiang; Lash, James P.; Kusek, John W.; Raj, Dominic S.

    2014-01-01

    Background Epigenetic mechanisms may be important in the progression of chronic kidney disease (CKD). Methods We studied the genome-wide DNA methylation pattern associated with rapid loss of kidney function using the Infinium HumanMethylation 450 K BeadChip in 40 Chronic Renal Insufficiency (CRIC) study participants (n = 3939) with the highest and lowest rates of decline in estimated glomerular filtration rate. Results The mean eGFR slope was 2.2 (1.4) and −5.1 (1.2) mL/min/1.73 m2 in the stable kidney function group and the rapid progression group, respectively. CpG islands in NPHP4, IQSEC1 and TCF3 were hypermethylated to a larger extent in subjects with stable kidney function (P-values of 7.8E−05 to 9.5E−05). These genes are involved in pathways known to promote the epithelial to mesenchymal transition and renal fibrosis. Other CKD-related genes that were differentially methylated are NOS3, NFKBIL2, CLU, NFKBIB, TGFB3 and TGFBI, which are involved in oxidative stress and inflammatory pathways (P-values of 4.5E−03 to 0.046). Pathway analysis using Ingenuity Pathway Analysis showed that gene networks related to cell signaling, carbohydrate metabolism and human behavior are epigenetically regulated in CKD. Conclusions Epigenetic modifications may be important in determining the rate of loss of kidney function in patients with established CKD. PMID:24516231

  10. Relationship of Estimated GFR and Coronary Artery Calcification in the (CRIC) Chronic Renal Insufficiency Cohort Study

    PubMed Central

    Budoff, Matthew J; Rader, Daniel J; Reilly, Muredach P.; Mohler, Emile R.; Lash, Jim; Yang, Wei; Rosen, Leigh; Glenn, Melanie; Teal, Valerie; Feldman, Harold I.

    2011-01-01

    Background Coronary artery calcification (CAC) is associated with increased mortality risk in the general population. Although individuals with chronic kidney disease (CKD) are at markedly increased mortality risk, the incidence, prevalence, and prognosis of CAC in CKD is not well-understood. Study Design Cross-sectional observational study. Setting and Participants Analysis of 1,908 participants who underwent coronary calcium scanning as part of the multi-ethnic CRIC (Chronic Renal Insufficiency Cohort) Study. Predictor Estimated glomerular filtration rate (eGFR) computed using the Modification of Diet in Renal Disease (MDRD) Study equation, stratified by race, sex and diabetic status. eGFR was treated as a continous variable and a categorical variable compared to the reference range of >60 ml/min/1.73 m2 Measurements CAC detected using CT scans using either an Imatron C-300 electron beam computed tomography scanner or multi-detector CT scanner. CAC was computed using the Agatston score, as a categorical variable. Analyses were performed using ordinal logistic regression. Results We found a strong and graded relationship between lower eGFR and increasing CAC. In unadjusted models, ORs increased from 1.68 (95% CI, 1.23–2.31) for eGFR from 50–59 to 2.82 (95% CI, 2.06–3.85) for eGFR of <30. Multivariable adjustment only partially attenuated the results (OR, 1.53; 95% CI, 1.07–2.20) for eGFR<30. Limitations Use of eGFR rather than measured GFR. Conclusions We demonstrated a graded relationship between severity of CKD and CAC, independent of traditional risk factors. These findings supports recent guidelines that state that if vascular calcification is present, it should be considered as a complementary component to be included in the decision making required for individualizing treatment of CKD. PMID:21783289

  11. Chronic Renal Insufficiency Cohort (CRIC) Study: Baseline Characteristics and Associations with Kidney Function

    PubMed Central

    Go, Alan S.; Appel, Lawrence J.; He, Jiang; Ojo, Akinlolu; Rahman, Mahboob; Townsend, Raymond R.; Xie, Dawei; Cifelli, Denise; Cohan, Janet; Fink, Jeffrey C.; Fischer, Michael J.; Gadegbeku, Crystal; Hamm, L. Lee; Kusek, John W.; Landis, J. Richard; Narva, Andrew; Robinson, Nancy; Teal, Valerie; Feldman, Harold I.

    2009-01-01

    Background and objectives: The Chronic Renal Insufficiency Cohort (CRIC) Study was established to examine risk factors for the progression of chronic kidney disease (CKD) and cardiovascular disease (CVD) in patients with CKD. We examined baseline demographic and clinical characteristics. Design, setting, participants, & measurements: Seven clinical centers recruited adults who were aged 21 to 74 yr and had CKD using age-based estimated GFR (eGFR) inclusion criteria. At baseline, blood and urine specimens were collected and information regarding health behaviors, diet, quality of life, and functional status was obtained. GFR was measured using radiolabeled iothalamate in one third of participants. Results: A total of 3612 participants were enrolled with mean age ± SD of 58.2 ± 11.0 yr; 46% were women, and 47% had diabetes. Overall, 45% were non-Hispanic white, 46% were non-Hispanic black, and 5% were Hispanic. Eighty-six percent reported hypertension, 22% coronary disease, and 10% heart failure. Mean body mass index was 32.1 ± 7.9 kg/m2, and 47% had a BP >130/80 mmHg. Mean eGFR was 43.4 ± 13.5 ml/min per 1.73 m2, and median (interquartile range) protein excretion was 0.17 g/24 h (0.07 to 0.81 g/24 h). Lower eGFR was associated with older age, lower socioeconomic and educational level, cigarette smoking, self-reported CVD, peripheral arterial disease, and elevated BP. Conclusions: Lower level of eGFR was associated with a greater burden of CVD as well as lower socioeconomic and educational status. Long-term follow-up of participants will provide critical insights into the epidemiology of CKD and its relationship to adverse outcomes. PMID:19541818

  12. Interleukin-6 Is a Risk Factor for Atrial Fibrillation in Chronic Kidney Disease: Findings from the CRIC Study

    PubMed Central

    Amdur, Richard L.; Mukherjee, Monica; Go, Alan; Barrows, Ian R.; Ramezani, Ali; Shoji, Jun; Reilly, Muredach P.; Gnanaraj, Joseph; Deo, Raj; Roas, Sylvia; Keane, Martin; Master, Steve; Teal, Valerie; Soliman, Elsayed Z.; Yang, Peter; Feldman, Harold; Kusek, John W.; Tracy, Cynthia M.; Raj, Dominic S.

    2016-01-01

    Atrial fibrillation (AF) is the most common sustained arrhythmia in patients with chronic kidney disease (CKD). In this study, we examined the association between inflammation and AF in 3,762 adults with CKD, enrolled in the Chronic Renal Insufficiency Cohort (CRIC) study. AF was determined at baseline by self-report and electrocardiogram (ECG). Plasma concentrations of interleukin(IL)-1, IL-1 Receptor antagonist, IL-6, tumor necrosis factor (TNF)-α, transforming growth factor-β, high sensitivity C-Reactive protein, and fibrinogen, measured at baseline. At baseline, 642 subjects had history of AF, but only 44 had AF in ECG recording. During a mean follow-up of 3.7 years, 108 subjects developed new-onset AF. There was no significant association between inflammatory biomarkers and past history of AF. After adjustment for demographic characteristics, comorbid conditions, laboratory values, echocardiographic variables, and medication use, plasma IL-6 level was significantly associated with presence of AF at baseline (Odds ratio [OR], 1.61; 95% confidence interval [CI], 1.21 to 2.14; P = 0.001) and new-onset AF (OR, 1.25; 95% CI, 1.02 to 1.53; P = 0.03). To summarize, plasma IL-6 level is an independent and consistent predictor of AF in patients with CKD. PMID:26840403

  13. Time-updated systolic blood pressure and the progression of chronic kidney disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study

    PubMed Central

    Anderson, Amanda H; Yang, Wei; Townsend, Raymond R; Pan, Qiang; Chertow, Glenn M; Kusek, John W; Charleston, Jeanne; He, Jiang; Kallem, RadhaKrishna; Lash, James P; Miller, Edgar R; Rahman, Mahboob; Steigerwalt, Susan; Weir, Matthew; Wright, Jackson T; Feldman, Harold I

    2015-01-01

    Background Blood pressure (BP) is often inadequately controlled in patients with chronic kidney disease (CKD). Previous reports of the longitudinal association between achieved level of BP and end-stage renal disease (ESRD) have not incorporated time-updated BP with appropriate adjustment for known confounders. Objective To assess the association between baseline and time-updated systolic BP (SBP) with the progression of CKD. Design Observational, prospective cohort study (ClinicalTrials.gov identifier: NCT00304148) Setting Seven US clinical centers Patients Participants of the Chronic Renal Insufficiency Cohort (CRIC) Study (N=3,708) followed for a median (25th, 75th percentiles) of 5.7 (4.6, 6.7) years Measurements The mean of three seated SBP measurements were used as the visit-specific SBP. SBP was time-updated as the mean of that visit and all prior visits. Outcomes were ESRD and the composite renal endpoint of ESRD (dialysis or transplantation) or halving of the estimated glomerular filtration rate (eGFR). Analyses investigating baseline and time-updated SBP utilized traditional Cox proportional hazards models and marginal structural models, respectively. Results SBP was ≥130 mmHg at all study visits in 19.2% of participants, and ≥140 mmHg in 10.6%. The hazard ratio (95% confidence interval) for ESRD among participants with SBP 130–139 mmHg, compared to SBP <120 mmHg, was 1.46 (1.13–1.88) using only baseline data, and was 2.37 (1.48–3.80) using all available time-updated data. Among those with SBP ≥140 mmHg, corresponding hazard ratios were 1.46 (1.18–1.88) and 3.37 (2.26–5.03), respectively. Limitations SBP was measured once annually, and the CRIC Study cohort is not a random sample. Conclusions Among participants in the CRIC Study, time-updated SBP over 130 mmHg was more strongly associated with progression of CKD than analyses based on baseline SBP. Funding The CRIC Study is funded under cooperative agreements from the National Institute of

  14. A Longitudinal Study of Left Ventricular Function and Structure from CKD to ESRD: The CRIC Study

    PubMed Central

    Keane, Martin; Delafontaine, Patrice; Dries, Daniel; Foster, Elyse; Gadegbeku, Crystal A.; Go, Alan S.; Hamm, L. Lee; Kusek, John W.; Ojo, Akinlolu O.; Rahman, Mahboob; Tao, Kaixiang; Wright, Jackson T.; Xie, Dawei; Hsu,, Chi-yuan

    2013-01-01

    Summary Background and objectives Abnormal left ventricular structure and function are associated with increased risk of adverse outcomes among patients with CKD and ESRD. A better understanding of changes in left ventricular mass and ejection fraction during the transition from CKD to ESRD may provide important insights to opportunities to improve cardiac outcomes. Design, setting, participants, & measurements This was a longitudinal study of a subset of participants of the Chronic Renal Insufficiency Cohort who were enrolled from 2003 to 2007 and followed through January of 2011. Participants were included if they had serial echocardiograms performed at advanced CKD (defined as estimated GFR<20 ml/min per 1.73 m2) and again after ESRD (defined as need for hemodialysis or peritoneal dialysis). Results A total of 190 participants (44% female, 66% black) had echocardiograms during advanced CKD and after ESRD. Mean (SD) estimated GFR at advanced CKD was 16.9 (3.5) ml/min per 1.73 m2. Mean (SD) time between the advanced CKD echocardiogram and ESRD echocardiogram was 2.0 (1.0) years. There was no significant change in left ventricular mass index (62.3–59.5 g/m2.7, P=0.10) between advanced CKD and ESRD; however, ejection fraction significantly decreased (53%–50%, P=0.002). Interactions for age, race, dialysis modality, and diabetes status were not significant (P>0.05). Conclusions Mean left ventricular mass index did not change significantly from advanced CKD to ESRD; however, ejection fraction declined during this transition period. Although left ventricular mass index is fixed by advanced stages of CKD, ejection fraction decline during more advanced stages of CKD may be an important contributor to cardiovascular disease and mortality after dialysis. PMID:23411431

  15. Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study

    PubMed Central

    Fink, Jeffrey C.; Ojo, Akinlolu O.; Barrows, Ian R.; Reilly, Muredach P.; Townsend, Raymond R.; Joffe, Marshall M.; Rosas, Sylvia E.; Wolman, Melanie; Patel, Samir S.; Keane, Martin G.; Feldman, Harold I.; Kusek, John W.; Raj, Dominic S.

    2015-01-01

    Background Left ventricular hypertrophy (LVH) and myocardial contractile dysfunction are independent predictors of mortality in patients with chronic kidney disease (CKD). The association between inflammatory biomarkers and cardiac geometry has not yet been studied in a large cohort of CKD patients with a wide range of kidney function. Methods Plasma levels of interleukin (IL)-1β, IL-1 receptor antagonist (IL-1RA), IL-6, tumor necrosis factor (TNF)-α, transforming growth factor (TGF)-β, high-sensitivity C-Reactive protein (hs-CRP), fibrinogen and serum albumin were measured in 3,939 Chronic Renal Insufficiency Cohort study participants. Echocardiography was performed according to the recommendations of the American Society of Echocardiography and interpreted at a centralized core laboratory. Results LVH, systolic dysfunction and diastolic dysfunction were present in 52.3%, 11.8% and 76.3% of the study subjects, respectively. In logistic regression analysis adjusted for age, sex, race/ethnicity, diabetic status, current smoking status, systolic blood pressure, urinary albumin- creatinine ratio and estimated glomerular filtration rate, hs-CRP (OR 1.26 [95% CI 1.16, 1.37], p<0.001), IL-1RA (1.23 [1.13, 1.34], p<0.0001), IL-6 (1.25 [1.14, 1.36], p<0.001) and TNF-α (1.14 [1.04, 1.25], p = 0.004) were associated with LVH. The odds for systolic dysfunction were greater for subjects with elevated levels of hs-CRP (1.32 [1.18, 1.48], p<0.001) and IL-6 (1.34 [1.21, 1.49], p<0.001). Only hs-CRP was associated with diastolic dysfunction (1.14 [1.04, 1.26], p = 0.005). Conclusion In patients with CKD, elevated plasma levels of hs-CRP and IL-6 are associated with LVH and systolic dysfunction. PMID:25909952

  16. STS ancillary equipment study. User reference book

    NASA Technical Reports Server (NTRS)

    Plough, J. A.

    1977-01-01

    A record of what is currently known about STS ancillary equipment is presented in this user-oriented design so that a potential user may evaluate whether he could use the described ancillary equipment or if he would need to design and fabricate a payload-unique item. References that the user can use to obtain additional details and requirements to aid in his evaluation and decision are included.

  17. Ancillary study management systems: a review of needs

    PubMed Central

    2013-01-01

    Background The valuable clinical data, specimens, and assay results collected during a primary clinical trial or observational study can enable researchers to answer additional, pressing questions with relatively small investments in new measurements. However, management of such follow-on, “ancillary” studies is complex. It requires coordinating across institutions, sites, repositories, and approval boards, as well as distributing, integrating, and analyzing diverse data types. General-purpose software systems that simplify the management of ancillary studies have not yet been explored in the research literature. Methods We have identified requirements for ancillary study management primarily as part of our ongoing work with a number of large research consortia. These organizations include the Center for HIV/AIDS Vaccine Immunology (CHAVI), the Immune Tolerance Network (ITN), the HIV Vaccine Trials Network (HVTN), the U.S. Military HIV Research Program (MHRP), and the Network for Pancreatic Organ Donors with Diabetes (nPOD). We also consulted with researchers at a range of other disease research organizations regarding their workflows and data management strategies. Lastly, to enhance breadth, we reviewed process documents for ancillary study management from other organizations. Results By exploring characteristics of ancillary studies, we identify differentiating requirements and scenarios for ancillary study management systems (ASMSs). Distinguishing characteristics of ancillary studies may include the collection of additional measurements (particularly new analyses of existing specimens); the initiation of studies by investigators unaffiliated with the original study; cross-protocol data pooling and analysis; pre-existing participant consent; and pre-existing data context and provenance. For an ASMS to address these characteristics, it would need to address both operational requirements (e.g., allocating existing specimens) and data management requirements

  18. Classroom Utilization of Ancillary Personnel: Delivery Systems for Mainstreaming in Elementary Social Studies.

    ERIC Educational Resources Information Center

    Rockoff, Edward

    1979-01-01

    Proposes in-service training on the utilization of ancillary personnel (special education teacher, school nurse, hearing and speech clinician, guidance counselor) in assisting the social studies teacher with the mainstreamed student. Outlines how ancillary personnel may aid in preparing students for entrance into the regular classroom, developing…

  19. Do Ancillary Studies Aid Detection and Classification of Barrett Esophagus?

    PubMed

    Panarelli, Nicole C; Yantiss, Rhonda K

    2016-08-01

    Barrett esophagus is a preneoplastic condition defined by the presence of intestinal metaplasia (ie, goblet cells) in an endoscopically apparent columnar-lined esophagus. Dysplasia is the most important risk factor for cancer development among patients with Barrett esophagus; approximately 6% of patients with high-grade dysplasia progress to adenocarcinoma within 1 year. Surgical pathologists are generally expected to address 2 clinical concerns when evaluating mucosal biopsy samples from patients with suspected Barrett esophagus; they should note the presence, or absence, of goblet cells and comment on the grade of dysplasia when it is identified. Biopsy samples from patients with Barrett esophagus are categorized as negative for dysplasia, indefinite for dysplasia, or positive for dysplasia; in the latter situation, the severity of dysplasia is classified as low or high grade. Several histochemical stains, immunohistochemical stains, and molecular techniques can be used to facilitate detection of goblet cells and classify dysplasia in patients with Barrett esophagus, although their added value to routine morphologic assessment is not entirely clear. The purpose of this review is to discuss the state of the art regarding application of ancillary studies to esophageal samples from patients with a columnar-lined esophagus. PMID:27096258

  20. The Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study: Sample, Design, and Procedures

    PubMed Central

    Gallo, Linda C.; Penedo, Frank J.; Carnethon, Mercedes; Isasi, Carmen; Sotres-Alvarez, Daniela; Malcarne, Vanessa L.; Roesch, Scott C.; Youngblood, Marston E.; Daviglus, Martha L.; Gonzalez, Patricia; Talavera, Gregory P.

    2014-01-01

    Objectives The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Sociocultural Ancillary Study aims to examine associations between sociocultural and psychosocial factors and cardiovascular disease (CVD) and metabolic syndrome prevalence in Hispanics/Latinos. The conceptual framework is based on the Reserve Capacity and Lifespan Biopsychosocial Models, which emphasize multiple risk and protective pathways underlying socioeconomic and ethnic influences in health. This study describes the rationale, participants, and procedures for the HCHS/SOL Sociocultural Ancillary Study. Design and Setting The Sociocultural Ancillary Study to the HCHS/SOL is a cross-sectional cohort study with future opportunities for prospective investigation. Participants Participants were 5,313 adults, aged 18-74 years, of self-identified Hispanic/Latino descent and representing multiple Hispanic/Latino background groups, recruited from the Bronx, NY, Chicago, IL, Miami, FL, and San Diego, CA. Intervention Participants completed an interview-administered sociocultural assessment battery within 9 months of their HCHS/SOL clinical baseline exam. Outcome Measures The primary outcomes are CVD and the metabolic syndrome and its component risk factors. Results The Sociocultural Ancillary Study sample is broadly representative of the HCHS/SOL cohort. Weighted demographics are: 55% male, 56% 18-44 years, 44% 45 years and older, and 37% Mexican, 20% Cuban, 16% Puerto Rican, 12% Dominican, 8% Central American, and 5% South American descent. Conclusions By testing theoretically driven hypotheses concerning sociocultural and psychosocial factors in CVD, the Sociocultural Ancillary Study seeks to inform future prevention and intervention efforts for U.S. Hispanic/Latinos. PMID:24620452

  1. Manned maneuvering unit mission definition study. Volume 3: MMU ancillary support equipment and attachment concepts

    NASA Technical Reports Server (NTRS)

    1975-01-01

    An analysis of Manned Maneuvering Units (MMU) ancillary support equipment and attachment concepts is presented. The major objectives of the study are defined as: (1) identifying MMU applications which would supplement space shuttle safety and effectiveness, (2) to define general MMU performance and control requirements to satisfy candidate shuttle applications, (3) to develop concepts for attaching MMUs to various worksites and equipment, and (4) to identify requirements and develop concepts for MMU ancillary equipment.

  2. Serum aldosterone and death, end-stage renal disease, and cardiovascular events in blacks and whites: findings from the Chronic Renal Insufficiency Cohort (CRIC) Study.

    PubMed

    Deo, Rajat; Yang, Wei; Khan, Abigail M; Bansal, Nisha; Zhang, Xiaoming; Leonard, Mary B; Keane, Martin G; Soliman, Elsayed Z; Steigerwalt, Susan; Townsend, Raymond R; Shlipak, Michael G; Feldman, Harold I

    2014-07-01

    Prior studies have demonstrated that elevated aldosterone concentrations are an independent risk factor for death in patients with cardiovascular disease. Limited studies, however, have evaluated systematically the association between serum aldosterone and adverse events in the setting of chronic kidney disease. We investigated the association between serum aldosterone and death and end-stage renal disease in 3866 participants from the Chronic Renal Insufficiency Cohort. We also evaluated the association between aldosterone and incident congestive heart failure and atherosclerotic events in participants without baseline cardiovascular disease. Cox proportional hazards models were used to evaluate independent associations between elevated aldosterone concentrations and each outcome. Interactions were hypothesized and explored between aldosterone and sex, race, and the use of loop diuretics and renin-angiotensin-aldosterone system inhibitors. During a median follow-up period of 5.4 years, 587 participants died, 743 developed end-stage renal disease, 187 developed congestive heart failure, and 177 experienced an atherosclerotic event. Aldosterone concentrations (per SD of the log-transformed aldosterone) were not an independent risk factor for death (adjusted hazard ratio, 1.00; 95% confidence interval, 0.93-1.12), end-stage renal disease (adjusted hazard ratio, 1.07; 95% confidence interval, 0.99-1.17), or atherosclerotic events (adjusted hazard ratio, 1.04; 95% confidence interval, 0.85-1.18). Aldosterone was associated with congestive heart failure (adjusted hazard ratio, 1.21; 95% confidence interval, 1.02-1.35). Among participants with chronic kidney disease, higher aldosterone concentrations were independently associated with the development of congestive heart failure but not for death, end-stage renal disease, or atherosclerotic events. Further studies should evaluate whether mineralocorticoid receptor antagonists may reduce adverse events in individuals with

  3. Selected inflammatory imitators of mycosis fungoides: histologic features and utility of ancillary studies.

    PubMed

    Arps, David P; Chen, Stephanie; Fullen, Douglas R; Hristov, Alexandra C

    2014-10-01

    Mycosis fungoides is the most common primary cutaneous lymphoma; however, it remains a significant diagnostic challenge, in part because of the overlap with several inflammatory dermatoses. Despite advances in immunohistochemistry and molecular diagnostics, false-positive, false-negative, and indeterminate diagnoses are not uncommon. In most cases, the overall balance of morphologic, immunophenotypic, and genetic features must be considered carefully because there are few sensitive and specific clues to the diagnosis. Moreover, an appropriate clinical presentation is essential to the diagnosis and helps to favor or exclude inflammatory/reactive processes. Herein, we discuss 3 important inflammatory dermatoses that may closely simulate mycosis fungoides, and we review the use of ancillary studies in these challenging cases. PMID:25268195

  4. Adherence to inhaled corticosteroids: An ancillary study of the Childhood Asthma Management Program clinical trial

    PubMed Central

    Krishnan, Jerry A.; Bender, Bruce G.; Wamboldt, Frederick S.; Szefler, Stanley J.; Adkinson, N. Franklin; Zeiger, Robert S.; Wise, Robert A.; Bilderback, Andrew L.; Rand, Cynthia S.

    2011-01-01

    Background Information comparing subjective and objective measurements of adherence to study medications and the effects of adherence on treatment-related differences in asthma clinical trials are limited. Objective We sought to compare subjective and objective measurements of children’s adherence to inhaled corticosteroids or placebo and to determine whether adherence to study medications modified treatment-related differences in outcomes. Methods In an ancillary study conducted in 3 of 8 Childhood Asthma Management Program Clinical Centers, adherence was assessed by using self-reported and objective data in 5- to 12-year-old children with mild or moderate asthma who were randomly assigned to 200 μg of inhaled budesonide twice per day (n = 84) or placebo (n = 56) for 4 years. The κ statistic was used to evaluate agreement between self-reported adherence (daily diary cards) and objectively measured adherence (number of doses left in study inhalers). Multivariable analyses were used to determine whether adherence to study treatment modified treatment-related differences in outcomes. Results Adherence of less than 80% was seen in 75% of 140 children when adherence was measured objectively but only in 6% of children when measured by means of self-report. There was poor agreement between objective and subjective measurements of adherence of at least 80% (κ = 0.00; 95% CI, −0.05 to 0.04); self-reported adherence over the 4-year period generally overestimated objectively measured adherence (93.6% vs 60.8%, P < .0001). There was little evidence to indicate that adherence modified treatment-related differences in outcomes. Conclusion Researchers should use objective rather than self-reported adherence data to identify clinical trial participants with low levels of adherence to study treatment. PMID:22104610

  5. Cardiovascular Fat, Menopause, and Sex Hormones in Women: The SWAN Cardiovascular Fat Ancillary Study

    PubMed Central

    Shields, Kelly J.; Janssen, Imke; Hanley, Carrie; Budoff, Matthew J.; Barinas-Mitchell, Emma; Everson-Rose, Susan A.; Powell, Lynda H.; Matthews, Karen A.

    2015-01-01

    Context: Cardiovascular risk increases in women after menopause. Mounting evidence demonstrates a role of cardiovascular fat (CF) in the pathogenesis of coronary heart disease, but no research has examined CF in relation to sex hormones or menopausal status in women. Objective: The objective was to determine the relationship between CF depots, menopausal status, and endogenous sex hormones. Design: Cross-sectional and longitudinal study designs were used. Setting: The setting included the Study of Women's Health Across the Nation (SWAN) Heart and Cardiovascular Fat Ancillary Study. Participants: A total of 456 women (mean age, 50.75 y); 62% premenopausal/early perimenopausal, and 38% late peri-/postmenopausal. Intervention: Menopausal status, endogenous sex hormones measured simultaneously with CF volumes, and circulating estradiol available 4.80 years (median) before CF measures. Main Outcome Measures: Volumes of CF (epicardial adipose tissue [EAT], paracardial adipose tissue [PAT], total heart adipose tissue [TAT = EAT + PAT], and aortic perivascular adipose tissue [PVAT]). Results: In final models, late peri-/postmenopausal women had 9.88% more EAT, 20.72% more PAT, and 11.69% more TAT volumes than pre-/early perimenopausal women (P < .05). PVAT was not associated with menopausal status. In final models, lower estradiol concentrations were associated with greater volumes of PAT and TAT (P < .05). Women with the greatest reduction in estradiol since baseline had greater volumes of PAT compared to women with the least reduction (P = .02). Conclusions: Late peri-/postmenopausal women have greater volumes of heart fat compared with pre-/early perimenopausal women independent of age, obesity, and other covariates. Endogenous sex hormones are associated with CF. Perhaps CF plays a role in the higher risk of coronary heart disease reported in women after menopause. PMID:26176800

  6. Prevalence and Correlates of Perceived Ethnic Discrimination in the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study

    PubMed Central

    Arellano-Morales, Leticia; Roesch, Scott C.; Gallo, Linda C.; Emory, Kristen T.; Molina, Kristine M.; Gonzalez, Patricia; Penedo, Frank J.; Navas-Nacher, Elena L.; Teng, Yanping; Deng, Yu; Isasi, Carmen R.; Schneiderman, Neil; Brondolo, Elizabeth

    2015-01-01

    Empirical studies examining perceived ethnic discrimination in Latinos of diverse background groups are limited. This study examined prevalence and correlates of discrimination in a diverse sample of U.S. Latinos (N=5,291) from the multi-site Hispanic Community Health Study/Study of Latinos (HCHS/SOL) and HCHS/SOL Sociocultural Ancillary Study. The sample permitted an examination of differences across seven groups (Central American, Cuban, Dominican, Mexican, Puerto Rican, South American, and Other/Multiple Background). Most participants (79.5%) reported lifetime discrimination exposure and prevalence rates ranged from 64.9% to 98% across groups. Structural Equation Models (SEM) indicated that after adjusting for sociodemographic covariates most group differences in reports of discrimination were eliminated. However, Cubans reported the lowest levels of discrimination, overall among all groups. Furthermore, regional effects were more important than group effects. Participants from Chicago reported the highest levels of discrimination in comparison to other regions. Group differences among Latinos appear to be primarily a function of sociodemographic differences in education, income, and acculturation. In addition, differences in exposure to discrimination may be tied to variables associated with both immigration patterns and integration to U.S. culture. Results highlight the importance of considering historical context and the intersection of discrimination and immigration when evaluating the mental health of Latinos. PMID:26491624

  7. STS users study (study 2.2). Volume 3: Ancillary equipment study

    NASA Technical Reports Server (NTRS)

    Pritchard, E. I.

    1975-01-01

    The multi-mission support equipment (MMSE) applicable to six payloads is studied. Tables indicate individual satellite projects to which each MMSE is applicable, and which equipments are applicable to multiple payload configurations when more than one project's payload would be flown on the STS. An estimate of the first date on which interface definition information needed by a payload project are also shown.

  8. Cell blocks in cytopathology: a review of preparative methods, utility in diagnosis and role in ancillary studies.

    PubMed

    Jain, D; Mathur, S R; Iyer, V K

    2014-12-01

    The cell block (CB) is a routine procedure in cytopathology that has gained importance because of its pivotal role in diagnosis and ancillary studies. There is no precise review in the published literature that deals with the various methods of preparation of CB, its utility in diagnosis, immunocytochemistry (ICC) or molecular testing, and its drawbacks. An extensive literature search on CB in cytology using internet search engines was performed for this review employing the following keywords: cell block, cytoblock, cytology, cytopathology, methods, preparation, fixatives, diagnostic yield, ancillary and molecular studies. Ever since its introduction more than a century ago, the CB technique has undergone numerous modifications to improve the quality of the procedure; however, the overall principle remains the same in each method. CBs can be prepared from virtually all varieties of cytological samples. In today's era of personalized medicine, cytological specimens, including CBs, augment the utility of cytological samples in analysing the molecular alterations as effectively as surgical biopsies or resection specimens. With the availability of molecular targeted therapy for many cancers, a large number of recent studies have used cytological material or CBs for molecular characterization. The various techniques of CB preparation with different fixatives, their advantages and limitations, and issues of diagnostic yield are discussed in this review. PMID:25113785

  9. Demand Response for Ancillary Services

    SciTech Connect

    Alkadi, Nasr E; Starke, Michael R

    2013-01-01

    Many demand response resources are technically capable of providing ancillary services. In some cases, they can provide superior response to generators, as the curtailment of load is typically much faster than ramping thermal and hydropower plants. Analysis and quantification of demand response resources providing ancillary services is necessary to understand the resources economic value and impact on the power system. Methodologies used to study grid integration of variable generation can be adapted to the study of demand response. In the present work, we describe and illustrate a methodology to construct detailed temporal and spatial representations of the demand response resource and to examine how to incorporate those resources into power system models. In addition, the paper outlines ways to evaluate barriers to implementation. We demonstrate how the combination of these three analyses can be used to translate the technical potential for demand response providing ancillary services into a realizable potential.

  10. MSM in HIV-prevention trials are sexual partners with each other: An ancillary study to the EXPLORE intervention.

    PubMed

    Mimiaga, Matthew J; Safren, Steven A; Benet, Dana Jones; Manseau, Marc W; DeSousa, Nancy; Mayer, Kenneth H

    2006-01-01

    The EXPLORE study evaluated a behavioral intervention to prevent HIV seroconversion among men who have sex with men (MSM). The present ancillary study enrolled 345 EXPLORE participants at one study site (Boston) and assessed high-risk sexual behavior with other EXPLORE participants. It also assessed sexual intentions across other EXPLORE participants, HIV-negative individuals, and unknown HIV serostatus partners. Thirty-one percent reported having sex with another EXPLORE participant: 27% unprotected receptive oral sex with ejaculation (UO), 30% unprotected insertive anal sex (UIA), and 34% reported unprotected receptive anal sex (URA). Significant relationships between intentions to engage in UO, UIA, and URA, and type of partner emerged with intentions to engage in UO, UIA, and URA higher in HIV-negative partners, other EXPLORE participants, and unknown-HIV serostatus partners. Future HIV-prevention studies recruiting MSM at increased sexual risk of HIV infection should address participants potentially becoming sexual partners with each other. PMID:16331532

  11. Ancillary Benefits for Caregivers of Children with Asthma Participating in an Environmental Intervention Study to Alleviate Asthma Symptoms

    PubMed Central

    Kubzansky, Laura D.; Spengler, John D.; Levy, Jonathan I.

    2009-01-01

    Providing care for children with asthma can be demanding and time-intensive with far-reaching effects on caregivers’ lives. Studies have documented childhood asthma symptom reductions and improved asthma-related quality of life (AQOL) with indoor allergen-reducing environmental interventions. Few such studies, however, have considered ancillary benefits to caregivers or other family members. Ancillary benefits could be derived from child health improvements and reduced caregiving burden or from factors such as improved living environments or social support that often accompanies intensive residential intervention efforts. As part of the Boston Healthy Public Housing Initiative (HPHI), a longitudinal single-cohort intervention study of asthmatic children, we examined trends in caregivers’ quality of life related to their child’s asthma (caregiver AQOL) using monthly Juniper Caregiver Asthma Quality of Life Questionnaires (AQLQ) for 32 primary caregivers to 42 asthmatic children aged 4 to 17 years. Longitudinal analyses were used to examine caregiver AQOL trends and their relationship to the child’s AQOL, then to consider additional predictors of caregiver AQOL. Caregiver AQLQ improved significantly over the course of the study with overall improvements significantly correlated with child AQOL (p = 0.005). However, caregiver AQOL improved most in the months before environmental interventions, while children’s AQOL improved most in the months following. Time trends in caregiver AQOL, controlling for child AQOL, were not explained by available social support or caregiver stress measures. Our findings suggest potential participation effects not adequately captured by standard measures. Future environmental intervention studies should more formally consider social support and participation effects for both children and caregivers PMID:19184446

  12. Ancillary benefits for caregivers of children with asthma participating in an environmental intervention study to alleviate asthma symptoms.

    PubMed

    Clougherty, Jane E; Kubzansky, Laura D; Spengler, John D; Levy, Jonathan I

    2009-03-01

    Providing care for children with asthma can be demanding and time-intensive with far-reaching effects on caregivers' lives. Studies have documented childhood asthma symptom reductions and improved asthma-related quality of life (AQOL) with indoor allergen-reducing environmental interventions. Few such studies, however, have considered ancillary benefits to caregivers or other family members. Ancillary benefits could be derived from child health improvements and reduced caregiving burden or from factors such as improved living environments or social support that often accompanies intensive residential intervention efforts. As part of the Boston Healthy Public Housing Initiative (HPHI), a longitudinal single-cohort intervention study of asthmatic children, we examined trends in caregivers' quality of life related to their child's asthma (caregiver AQOL) using monthly Juniper Caregiver Asthma Quality of Life Questionnaires (AQLQ) for 32 primary caregivers to 42 asthmatic children aged 4 to 17 years. Longitudinal analyses were used to examine caregiver AQOL trends and their relationship to the child's AQOL, then to consider additional predictors of caregiver AQOL. Caregiver AQLQ improved significantly over the course of the study with overall improvements significantly correlated with child AQOL (p = 0.005). However, caregiver AQOL improved most in the months before environmental interventions, while children's AQOL improved most in the months following. Time trends in caregiver AQOL, controlling for child AQOL, were not explained by available social support or caregiver stress measures. Our findings suggest potential participation effects not adequately captured by standard measures. Future environmental intervention studies should more formally consider social support and participation effects for both children and caregivers. PMID:19184446

  13. Macular Pigment Imaging in AREDS2 Participants: An Ancillary Study of AREDS2 Subjects Enrolled at the Moran Eye Center

    PubMed Central

    Bernstein, Paul S.; Ahmed, Faisal; Liu, Aihua; Allman, Susan; Sheng, Xiaoming; Sharifzadeh, Mohsen; Ermakov, Igor; Gellermann, Werner

    2012-01-01

    Purpose. Age-Related Eye Disease Study 2 (AREDS2) is a randomized, placebo-controlled study designed to determine whether supplementation with 10 mg of lutein and 2 mg of zeaxanthin per day can slow the rate of progression of age-related macular degeneration (AMD). Although some biomarkers of response to carotenoid supplementation such as serum concentrations are part of the AREDS2 protocol, measurement of carotenoid concentrations in the eye and other tissues is not. In this approved ancillary study, macular pigment optical density (MPOD), macular pigment distributions, and skin carotenoid levels at enrollment and at each annual visit were measured to assess baseline carotenoid status and to monitor response to assigned interventions. Methods. All subjects enrolled at the Moran Eye Center had MPOD and macular pigment spatial distributions measured by dual-wavelength autofluorescence imaging and total skin carotenoids measured by resonance Raman spectroscopy. Results. Baseline MPOD in enrolled subjects was unusually high relative to an age-matched control group that did not consume carotenoid supplements regularly, consistent with the high rate of habitual lutein and zeaxanthin consumption in Utah AREDS2 subjects prior to enrollment. MPOD did not correlate with serum or skin carotenoid measurements. Conclusions. Useful information is provided through this ancillary study on the ocular carotenoid status of AREDS2 participants in the target tissue of lutein and zeaxanthin supplementation: The macula. When treatment assignments are unmasked at the conclusion of the study, unique tissue-based insights will be provided on the progression of AMD in response to long-term, high-dose carotenoid supplementation versus diet alone. (ClinicalTrials.gov number, NCT00345176.) PMID:22879423

  14. Finisher hog production in the Southeastern United States: Ancillary measurements derived from the National Air Emissions Monitoring Study (NAEMS)

    NASA Astrophysics Data System (ADS)

    Robarge, W. P.; Lee, S.; Walker, J. T.

    2010-12-01

    Measurements of emissions of gases and fine particulate matter from swine animal feeding operations (AFOs) in the southeastern US have typically been confined to relatively short periods (days to several weeks) and have generally focused on waste lagoons. Access to swine animal housing units and other ancillary information has been limited. The National Air Emissions Monitoring Study (NAEMS) provided a unique opportunity to characterize emissions from swine housing units for an extended period of time (~ 2 years), and allowed access to ancillary measurements regarding nutrient flows (feed amounts and composition), manure dynamics, animal inventories, water usage and farm management. Presented here is a summary of the observations made for a NAEMS finisher site (NC3B) selected as being representative of swine production in the southeastern US. Finisher hogs are raised in rotations (~ 140 days) with a target market weight of 123 kg/hog. Among the population during a rotation (700-800 hogs/barn) the actual growth rate varies with a series of “grade-outs” of market-weight hogs starting ~ 110 days from initial load-in. Derivation of the standing live-weight in the barns during a rotation therefore requires use of a growth model and summation over several different “populations” of hogs within a single barn. Up to 5 different feed formulations are fed during a rotation with %N content ranging from (3.4 to 2.2% N; total feed consumed 181,000 kg/barn). Across 4 complete rotations, N consumed was ~50 g N per hog/day. Of this amount, we estimate ~ 60% is excreted as fecal matter and urine. The TAN (NH3 + NH4+) content of the shallow pits is consistently higher (1880 ±390 mg TAN/L) than that found in the anaerobic lagoon (800 ±70 mg TAN/L), except immediately after recharge following pit-pull (pH of the two liquids was similar). The presence of a recalcitrant layer of sludge in the shallow pits (liquid height = 20 cm; sludge depth = 5-10 cm; TAN = 2500 mg N/L; total

  15. Ancillary services market in California

    SciTech Connect

    Gomez, T.; Marnay, C.; Siddiqui, A.; Liew, L.; Khavkin, M.

    1999-07-01

    This report includes sections on the following topics: (1) California restructured electricity system overview; (2) Reliability criteria; (3) Design of the California ISO ancillary services market; (4) Operation of ancillary services markets; (5) Ancillary services markets redesign; and (6) Conclusions.

  16. Study of Droplet Activation in Thin Clouds Using Ground-Based Raman Lidar and Ancillary Remote Sensors

    NASA Astrophysics Data System (ADS)

    Rosoldi, Marco; Madonna, Fabio; Gumà Claramunt, Pilar; Pappalardo, Gelsomina

    2016-06-01

    A methodology for the study of cloud droplet activation based on the measurements performed with ground-based multi-wavelength Raman lidars and ancillary remote sensors collected at CNR-IMAA observatory, Potenza, South Italy, is presented. The study is focused on the observation of thin warm clouds. Thin clouds are often also optically thin: this allows the cloud top detection and the full profiling of cloud layers using ground-based Raman lidar. Moreover, broken clouds are inspected to take advantage of their discontinuous structure in order to study the variability of optical properties and water vapor content in the transition from cloudy regions to cloudless regions close to the cloud boundaries. A statistical study of this variability leads to identify threshold values for the optical properties, enabling the discrimination between clouds and cloudless regions. These values can be used to evaluate and improve parameterizations of droplet activation within numerical models. A statistical study of the co-located Doppler radar moments allows to retrieve droplet size and vertical velocities close to the cloud base. First evidences of a correlation between droplet vertical velocities measured at the cloud base and the aerosol effective radius observed in the cloud-free regions of the broken clouds are found.

  17. Chronic stress, inflammation, and glucose regulation in U.S. Hispanics from the HCHS/SOL Sociocultural Ancillary Study.

    PubMed

    McCurley, Jessica L; Mills, Paul J; Roesch, Scott C; Carnethon, Mercedes; Giacinto, Rebeca E; Isasi, Carmen R; Teng, Yanping; Sotres-Alvarez, Daniela; Llabre, Maria M; Penedo, Frank J; Schneiderman, Neil; Gallo, Linda C

    2015-08-01

    Diabetes prevalence is rising rapidly, and diabetes disproportionately affects Hispanics and other underserved groups. Chronic stress may contribute to diabetes risk, but few studies have examined this relationship in U.S. Hispanics. We examined associations of chronic stress with fasting glucose, glucose tolerance, and glycosylated hemoglobin (HbA1c) in Hispanics without diabetes, and also assessed indirect effects of stress through inflammation (CRP). Participants were 3,923 men and women, aged 18-74, without diabetes, from the four U.S. field centers (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Sociocultural Ancillary study. Participants completed a measure of chronic life stress and a physical exam with oral glucose tolerance test. In a multivariate regression analysis with adjustment for demographic and health covariates, higher chronic stress was related to higher fasting glucose (standardized regression coefficient: β = .09, p < .01), postload glucose (β = .07, p < .05), and HbA1c levels (β = .08, p < .01). However, there was no indirect effect of stress through inflammation. Findings suggest that higher chronic stress is associated with poorer glucose regulation in Hispanics, prior to the onset of a clinical diabetes diagnosis. PMID:25898909

  18. Chronic Stress, Inflammation, and Glucose Regulation in U.S. Hispanics from the HCHS/SOL Sociocultural Ancillary Study

    PubMed Central

    McCurley, Jessica L.; Mills, Paul J.; Roesch, Scott C.; Carnethon, Mercedes; Giacinto, Rebeca E.; Isasi, Carmen R.; Teng, Yanping; Sotres-Alvarez, Daniela; Llabre, Maria M.; Penedo, Frank J.; Schneiderman, Neil; Gallo, Linda C.

    2015-01-01

    Diabetes prevalence is rising rapidly, and diabetes disproportionately affects Hispanics and other underserved groups. Chronic stress may contribute to diabetes risk, but few studies have examined this relationship in U.S. Hispanics. We examined associations of chronic stress with fasting glucose, glucose tolerance, and glycosylated hemoglobin (HbA1c) in Hispanics without diabetes, and also assessed indirect effects of stress through inflammation (CRP). Participants were 3923 men and women, aged 18-74, without diabetes, from the four U.S. field centers (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)-Sociocultural Ancillary study. Participants completed a measure of chronic life stress and a physical exam with oral glucose tolerance test. In a multivariate regression analysis with adjustment for demographic and health covariates, higher chronic stress was related to higher fasting glucose (standardized regression coefficient: β=.09, p<0.01), post load glucose (β=.07, p<0.05), and HbA1c levels (β=.08, p<0.01). However, there was no indirect effect of stress through inflammation. Findings suggest that higher chronic stress is associated with poorer glucose regulation in Hispanics, prior to the onset of a clinical diabetes diagnosis. PMID:25898909

  19. N-Heterocyclic olefins as ancillary ligands in catalysis: a study of their behaviour in transfer hydrogenation reactions.

    PubMed

    Iturmendi, Amaia; García, Nestor; Jaseer, E A; Munárriz, Julen; Sanz Miguel, Pablo J; Polo, Victor; Iglesias, Manuel; Oro, Luis A

    2016-08-01

    The Ir(i) complexes [Ir(cod)(κP,C,P'-NHO(PPh2))]PF6 and [IrCl(cod)(κC-NHO(OMe))] (cod = 1,5-cyclooctadiene, NHO(PPh2) = 1,3-bis(2-(diphenylphosphanyl)ethyl)-2-methyleneimidazoline) and NHO(OMe) = 1,3-bis(2-(methoxyethyl)-2-methyleneimidazoline), both featuring an N-heterocyclic olefin ligand (NHO), have been tested in the transfer hydrogenation reaction; this representing the first example of the use of NHOs as ancillary ligands in catalysis. The pre-catalyst [Ir(cod)(κP,C,P'-NHO(PPh2))]PF6 has shown excellent activities in the transfer hydrogenation of aldehydes, ketones and imines using (i)PrOH as a hydrogen source, while [IrCl(cod)(κC-NHO(OMe))] decomposes throughout the reaction to give low yields of the hydrogenated product. Addition of one or two equivalents of a phosphine ligand to the latter avoids catalyst decomposition and significantly improves the reaction yields. The reaction mechanism has been investigated by means of stoichiometric studies and theoretical calculations. The formation of the active species ([Ir(κP,C,P'-NHO(PPh2))((i)PrO)]) has been proposed to occur via isopropoxide coordination and concomitant COD dissociation. Moreover, throughout the catalytic cycle the NHO moiety behaves as a hemilabile ligand, thus allowing the catalyst to adopt stable square planar geometries in the transition states, which reduces the energetic barrier of the process. PMID:27472896

  20. Using Dimmable Lighting for Regulation Capacity and Non-Spinning Reserves in the Ancillary Services Market. A Feasibility Study.

    SciTech Connect

    Rubinstein, Francis; Xiaolei, Li; Watson, David S.

    2010-12-03

    The objective of this Feasibility Study was to identify the potential of dimmable lighting for providing regulation capacity and contingency reserves if massively-deployed throughout the State. We found that one half of the total electric lighting load in the California commercial sector is bottled up in larger buildings that are greater an 50,000 square feet. Retrofitting large California buildings with dimmable lighting to enable fast DR lighting would require an investment of about $1.8 billion and a"fleet" of about 56 million dimming ballasts. By upgrading the existing installed base of lighting and controls (primarily in large commercial facilities) a substantial amount of ancillary services could be provided. Though not widely deployed, today's state-of-the art lighting systems, control systems and communication networks could be used for this application. The same lighting control equipment that is appropriate for fast DR is also appropriate for achieving energy efficiency with lighting on a daily basis. Thus fast DR can leverage the capabilities that are provided by a conventional dimming lighting control system. If dimmable lighting were massively deployed throughout large California buildings (because mandated by law, for example) dimmable lighting could realistically supply 380 MW of non-spinning reserve, 47percent of the total non-spinning reserves needed in 2007.

  1. Associations of Structural and Functional Social Support with Diabetes Prevalence in U.S. Hispanics/Latinos: Results from the HCHS/SOL Sociocultural Ancillary Study

    PubMed Central

    Gallo, Linda C.; Fortmann, Addie L.; McCurley, Jessica L.; Isasi, Carmen R.; Penedo, Frank J.; Daviglus, Martha L.; Roesch, Scott C.; Talavera, Gregory A.; Gouskova, Natalia; Gonzalez, Franklyn; Schneiderman, Neil; Carnethon, Mercedes R.

    2015-01-01

    Background Little research has examined associations of social support with diabetes (or other physical health outcomes) in Hispanics, who are at elevated risk. Purpose We examined associations between social support and diabetes prevalence in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Sociocultural Ancillary Study. Methods Participants were 5181 adults, 18–74 years old, representing diverse Hispanic backgrounds, who underwent baseline exam with fasting blood draw, oral glucose tolerance test, medication review, sociodemographic assessment, and sociocultural exam with functional and structural social support measures. Results In adjusted analyses, one standard deviation higher structural and functional social support related to 16% and 15% lower odds, respectively, of having diabetes. Structural and functional support were related to both previously diagnosed diabetes (OR = .84 and .88, respectively) and newly recognized diabetes prevalence (OR = .84 and .83, respectively). Conclusions Higher functional and structural social support are associated with lower diabetes prevalence in Hispanics/Latinos. PMID:25107504

  2. Ancillary effects of selected acid deposition control policies

    SciTech Connect

    Moe, R.J.; Lyke, A.J.; Nesse, R.J.

    1986-08-01

    NAPAP is examining a number of potential ways to reduce the precursors (sulfur dioxide and nitrogen oxides) to acid deposition. However, the policies to reduce acid deposition will have other physical, biological and economic effects unrelated to acid deposition. For example, control policies that reduce sulfur dioxide emissions may also increase visibility. The effects of an acid deposition policy that are unrelated to acid deposition are referred to as ''ancillary'' effects. This reserch identifies and characterizes the principle physical and economic ancillary effects associated with acid deposition control and mitigation policies. In this study the ancillary benefits associated with four specific acid deposition policy options were investigated. The four policy options investigated are: (1) flue gas desulfurization, (2) coal blending or switching, (3) reductions in automobile emissions of NO/sub x/, and (4) lake liming. Potential ancillary benefits of each option were identified and characterized. Particular attention was paid to the literature on economic valuation of potential ancillary effects.

  3. (abstract) Towards Ancillary Data Standards

    NASA Technical Reports Server (NTRS)

    Acton, Charles H.

    1997-01-01

    NASA's SPICE information system for archiving, distributing, and accessing spacecraft navigation, orientation, and other ancillary data is described. A proposal is made for the further evolution of this concept to an internationally useful standard, to be.

  4. Impact of Ancillary Subunits on Ventricular Repolarization

    PubMed Central

    Abbott, Geoffrey W.; Xu, Xianghua; Roepke, Torsten K.

    2007-01-01

    Voltage-gated potassium (Kv) channels generate the outward K+ ion currents that constitute the primary force in ventricular repolarization. Kv channels comprise tetramers of pore-forming α subunits and, in probably the majority of cases in vivo, ancillary or β subunits that help define the properties of the Kv current generated. Ancillary subunits can be broadly categorized as cytoplasmic or transmembrane, and can modify Kv channel trafficking, conductance, gating, ion selectivity, regulation and pharmacology. Because of their often profound effects on Kv channel function, studies of the molecular correlates of ventricular repolarization must take into account ancillary subunits as well as α subunits. Cytoplasmic ancillary subunits include the Kvβ subunits, which regulate a range of Kv channels and may link channel gating to redox potential; and the KChIPs, which appear most often associated with Kv4 subfamily channels that generate the ventricular Ito current. Transmembrane ancillary subunits include the MinK-related proteins (MiRPs) encoded by KCNE genes, which modulate members of most Kv α subunit subfamilies; and the putative 12-transmembrane domain KCR1 protein which modulates hERG. In some cases, such as the ventricular IKs channel complex, it is well-established that the KCNQ1 α subunit must co-assemble with the MinK (KCNE1) single transmembrane domain ancillary subunit for recapitulation of the characteristic, unusually slowly-activating IKs current. In other cases it is not so clear-cut, and in particular the roles of the other MinK-related proteins (MiRPs 1–4) in regulating cardiac Kv channels such as KCNQ1 and hERG in vivo are under debate. MiRP1 alters hERG function and pharmacology, and inherited MiRP1 mutations are associated with inherited and acquired arrhythmias, but controversy exists over the native role of MiRP1 in regulating hERG (and therefore ventricular IKr) in vivo. Some ancillary subunits may exhibit varied expression to shape

  5. The Relationship Between Serum 25-Hydroxyvitamin D Levels and Nuclear Cataract in the Carotenoid Age-Related Eye Study (CAREDS), an Ancillary Study of the Women's Health Initiative

    PubMed Central

    Rao, Prethy; Millen, Amy E.; Meyers, Kristin J.; Liu, Zhe; Voland, Rickie; Sondel, Sheri; Tinker, Lesley; Wallace, Robert B.; Blodi, Barbara A.; Binkley, Neil; Sarto, Gloria; Robinson, Jennifer; LeBlanc, Erin; Mares, Julie A.

    2015-01-01

    Purpose. To investigate the relationship between serum 25-hydroxyvitamin D (25[OH]D) levels and nuclear cataract among participants of the Carotenoids in Age-Related Eye Disease Study (CAREDS), an ancillary study of the Women's Health Initiative (WHI) Observational Study (OS). Methods. Nuclear cataract was assessed from slit lamp photographs (2001–2004) taken 6 years after collecting serum analyzed for 25(OH)D levels at WHI baseline (1994–1998) in 1278 CAREDS participants age 50 to 79 years. Multivariate (age, iris color, smoking, pulse pressure) odds ratios (ORs) for nuclear cataract (nuclear opacities > level 4 or cataract extraction) by quintiles of serum 25(OH)D were estimated using logistic regression. Results. No significant association was observed between serum 25(OH)D and nuclear cataract among women of all ages (age-adjusted OR [95% confidence interval (CI)] 0.97 [0.65–1.45]). However, there was a significant age interaction (P for interaction = 0.04). There were no significant associations in the women 70 years or older. In women younger than 70 years, we observed an inverse association between serum 25(OH)D and nuclear cataract (multivariate adjusted ORs [95% CI] 0.54 [0.29–0.99] and 0.66 [0.36–1.20] for quintiles 4 and 5 vs. 1, respectively; P = 0.03). Further adjustment for 25(OH)D determinants (body mass index, vitamin D intake, and UVB exposure) attenuated this association. Conclusions. Serum 25(OH)D levels were unrelated to nuclear opacities in this study sample. However, exploratory analyses suggest a protective association in women younger than 70 years. Further investigations of the relationship between vitamin D and nuclear lens opacities are warranted. PMID:26132781

  6. 18 CFR 35.40 - Ancillary services.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Ancillary services. 35... Sales of Electric Energy, Capacity and Ancillary Services at Market-Based Rates § 35.40 Ancillary services. A Seller may make sales of ancillary services at market-based rates only if it has...

  7. Glycemic Control among U.S. Hispanics/Latinos with Diabetes from the HCHS/SOL Sociocultural Ancillary Study: Do Structural and Functional Social Support Play a Role?

    PubMed Central

    Fortmann, Addie L.; Roesch, Scott C.; Penedo, Frank J.; Isasi, Carmen R.; Carnethon, Mercedes R.; Corsino, Leonor; Schneiderman, Neil; Daviglus, Martha L.; Teng, Yanping; Giachello, Aida; Gonzalez, Franklyn; Gallo, Linda C.

    2014-01-01

    Background Social support is one potential source of health-related resiliency in Hispanics with diabetes. Purpose This study examined relationships of structural (i.e., social integration) and functional (i.e., perceived) social support with glycemic control (glycosylated hemoglobin; HbA1c) in the Hispanic Community Health Study/Study of Hispanics (HCHS/SOL) Sociocultural Ancillary Study. Methods This study included 766 men and women representing multiple Hispanic ethnic backgrounds, aged 18-74 years, with diagnosed diabetes who completed fasting blood draw, medication review, and measures of sociodemographic factors, medical history, structural support (Cohen Social Network Index), and functional support (Interpersonal Support Evaluation List-12). Results After adjusting for sociodemographic covariates and medication, a one standard deviation increase in functional support was related to an 0.18 % higher HbA1c (p = 0.04). A similar trend was observed for structural support; however, this effect was non-significant in adjusted models. Conclusion Greater functional support was associated with poorer glycemic control in Hispanics. PMID:25107503

  8. Organochlorine compounds and trace elements in fish tissue and ancillary data for the Connecticut, Housatonic, and Thames river basins study unit, 1992-94

    USGS Publications Warehouse

    Coles, J.F.

    1996-01-01

    Concentrations of organochlorine compounds and trace elements were assayed in fish tissue collected from the Connecticut, Housatonic, and Thames River Basins Study Unit, 1992-94. These data were collected to determine the occurrence and distribution of organochlorine compounds and trace elements in the study unit. Ancillary data included are land-use categories by percentage of the sampling-site basins and the size, gender, and age of the individual fish collected for this study. Concentrations of 28 organochlorine compounds in composited whole fish samples were measured at 32 sites, and concentrations of 22 trace elements in composited fish liver samples were measured at 14 of the 32 sites. Most frequently detected organochlorines were DDT related compounds at 31 sites, total PCBs at 28 sites, and chlordane related compounds at 25 sites. Concentrations of total PCBs in fish tissue were generally higher at the large river sites than at the smaller tributary sites. Concentrations of chlordane-related compounds in fish tissue were higher at sites from more urbanized basins than at sites from predominately agriculture and forested basins. Concentrations of the DDT related compounds were undifferentiated among sites comprising different land uses. Trace elements detected at all 14 sites included boron, copper, iron, manganese, molybdenum, selenium, and zinc. Trace elements detected at 10 or more sites included arsenic, mercury, silver, strontium, and vanadium. Antimony, beryllium, and uranium were not detected at any site.

  9. How to perform a feasibility study and market analysis to determine if an ancillary service makes sense.

    PubMed

    Brockman, Ken

    2008-01-01

    A feasibility study, as the name implies, is a study of the viability of a business venture. The study is an analysis of the market potential of the new products or services to be offered and investigates the primary issues related to the new business. This article discusses the elements that are essential for a valid feasibility study. PMID:18061763

  10. Physician ancillary services: fad or fashion? Part 2.

    PubMed

    Reiboldt, John

    2006-01-01

    Ancillary services are quite fashionable in today's medical practice, but perhaps you've wondered if they were only a fad. If you're considering adding services to increase your revenue, you're not too late; this trend seems here to stay. Doing your homework and due diligence is key to the success of your ancillary business. Before introducing a service into your practice or investing in an ancillary venture, make sure that you get off on sound footing. Major investments call for experienced consulting and tapping into financial, operational, and legal specialists to address specific needs. Part 1 defined ancillary services and addressed performing the feasibility study and writing the business plan. In this second part, legal and regulatory issues, financing arrangements, opening, and operational and ongoing management elements critical to success are all explored. PMID:16562521

  11. Physician ancillary services: fad or fashion? Part 1.

    PubMed

    Reiboldt, John

    2005-01-01

    Ancillary services are quite fashionable in today's medical practice, but perhaps you've wondered if they are only a fad. If you're considering adding services to increase your revenue, you're not too late; this trend seems here to stay. Doing your homework and due diligence is key to the success of your ancillary service. Before introducing a service into your practice or investing in an ancillary venture, make sure that you get off on sound footing. Major investments call for experienced consulting and tapping into financial, operational, and legal specialists to address specific needs. Part 1 of this two-part article defines ancillary services and addresses the following topics: performing the feasibility study; writing the business plan; and addressing the legal and regulatory issues. Part 2 will discuss financing arrangements, opening, operational, and ongoing management elements critical to success. PMID:16471393

  12. Validation of interpersonal support evaluation list-12 (ISEL-12) scores among English- and Spanish-speaking Hispanics/Latinos from the HCHS/SOL Sociocultural Ancillary Study.

    PubMed

    Merz, Erin L; Roesch, Scott C; Malcarne, Vanessa L; Penedo, Frank J; Llabre, Maria M; Weitzman, Orit B; Navas-Nacher, Elena L; Perreira, Krista M; Gonzalez, Franklyn; Ponguta, Liliana A; Johnson, Timothy P; Gallo, Linda C

    2014-06-01

    The Interpersonal Support Evaluation List-12 (ISEL-12; Cohen, Mermelstein, Kamarck, & Hoberman, 1985) is broadly employed as a short-form measure of the traditional ISEL, which measures functional (i.e., perceived) social support. The ISEL-12 can be scored by summing the items to create an overall social support score; three subscale scores representing appraisal, belonging, and tangible social support have also been proposed. Despite extensive use, studies of the psychometric properties of ISEL-12 scores have been limited, particularly among Hispanics/Latinos, the largest and fastest growing ethnic group in the United States. The current study investigated the reliability and structural and convergent validity of ISEL-12 scores using data from 5,313 Hispanics/Latinos who participated in the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study. Participants completed measures in English or Spanish and identified their ancestry as Dominican, Central American, Cuban, Mexican, Puerto Rican, or South American. Cronbach's alphas suggested adequate internal consistency for the total score for all languages and ancestry groups; coefficients for the subscale scores were not acceptable. Confirmatory factor analyses revealed that the one-factor and three-factor models fit the data equally well. Results from multigroup confirmatory factor analyses supported a similar one-factor structure with equivalent response patterns and variances between language groups and ancestry groups. Convergent validity analyses suggested that the total social support score related to scores of social network integration, life engagement, perceived stress, and negative affect (depression, anxiety) in the expected directions. PMID:24320763

  13. Options for pricing ancillary services in a deregulated power system

    NASA Astrophysics Data System (ADS)

    Yamin, Hatim Yahya

    2001-07-01

    GENCOs in restructured systems are compensated for selling energy in the market. In a restructured market, a mechanism is required to entice participants in the market to provide ancillary services and to ensure adequate compensation that would guarantee its economic viability. The ISO controls the dispatch of generation, manages the reliability of the transmission grid, provides open access to the transmission, buys and provides ancillary services as required, coordinates day-ahead, hour-ahead schedules and performs real time balancing of load and generation, settles real time imbalances and ancillary services sales and purchases. The ISO, also, administers congestion management protocols for the transmission grid. Since the ISO does not own any generating units it must ensure that there is enough reserves for maintaining reliability according to FERC regulations, and sufficient unloaded generating capacity for balancing services in a real-time market. The ISO could meet these requirements by creating a competitive market for ancillary services, which are metered and remain unbundled to provide an accurate compensation for each supplier and cost to each consumer, In this study, we give an overview for restructuring and ancillary services in a restructured power marketplace. Also, we discuss the effect of GENCOs' actions in the competitive energy and ancillary service markets. In addition, we propose an auction market design for hedging ancillary service costs in California market. Furthermore, we show how to include the n-1 and voltage contingencies in security constrained unit commitment. Finally, we present two approaches for GENCOs' unit commitment in a restructured power market; one is based on game theory and the other is based on market price forecasting. In each of the two GENCOs' unit commitment approaches, we discuss the GENCOs' optimal bidding strategies in energy and ancillary service markets to maximize the GENCOs' profit.

  14. Trajectories of Preparation for Future Care among First-Degree Relatives of Alzheimer's Disease Patients: An Ancillary Study of ADAPT

    ERIC Educational Resources Information Center

    Mak, Wingyun; Sorensen, Silvia

    2012-01-01

    Purpose: This study examines the longitudinal patterns of Preparation for Future Care (PFC), defined as Awareness, Avoidance, Gathering Information, Decision Making, and Concrete Plans, in first-degree relatives of people with Alzheimer's disease (AD). Design and Methods: Eight time points across 6.5 years from a subsample of adults aged 70 years…

  15. Study of Droplet Activation in Thin Clouds Using Ground-based Raman Lidar and Ancillary Remote Sensors

    NASA Astrophysics Data System (ADS)

    Rosoldi, Marco; Madonna, Fabio; Gumà Claramunt, Pilar; Pappalardo, Gelsomina

    2015-04-01

    Studies on global climate change show that the effects of aerosol-cloud interactions (ACI) on the Earth's radiation balance and climate, also known as indirect aerosol effects, are the most uncertain among all the effects involving the atmospheric constituents and processes (Stocker et al., IPCC, 2013). Droplet activation is the most important and challenging process in the understanding of ACI. It represents the direct microphysical link between aerosols and clouds and it is probably the largest source of uncertainty in estimating indirect aerosol effects. An accurate estimation of aerosol-clouds microphysical and optical properties in proximity and within the cloud boundaries represents a good frame for the study of droplet activation. This can be obtained by using ground-based profiling remote sensing techniques. In this work, a methodology for the experimental investigation of droplet activation, based on ground-based multi-wavelength Raman lidar and Doppler radar technique, is presented. The study is focused on the observation of thin liquid water clouds, which are low or midlevel super-cooled clouds characterized by a liquid water path (LWP) lower than about 100 gm-2(Turner et al., 2007). These clouds are often optically thin, which means that ground-based Raman lidar allows the detection of the cloud top and of the cloud structure above. Broken clouds are primarily inspected to take advantage of their discontinuous structure using ground based remote sensing. Observations are performed simultaneously with multi-wavelength Raman lidars, a cloud Doppler radar and a microwave radiometer at CIAO (CNR-IMAA Atmospheric Observatory: www.ciao.imaa.cnr.it), in Potenza, Southern Italy (40.60N, 15.72E, 760 m a.s.l.). A statistical study of the variability of optical properties and humidity in the transition from cloudy regions to cloud-free regions surrounding the clouds leads to the identification of threshold values for the optical properties, enabling the

  16. Association of Childhood Economic Hardship with Adult Height and Adult Adiposity among Hispanics/Latinos. The HCHS/SOL Socio-Cultural Ancillary Study.

    PubMed

    Isasi, Carmen R; Jung, Molly; Parrinello, Christina M; Kaplan, Robert C; Kim, Ryung; Crespo, Noe C; Gonzalez, Patricia; Gouskova, Natalia A; Penedo, Frank J; Perreira, Krista M; Perrino, Tatiana; Sotres-Alvarez, Daniela; Van Horn, Linda; Gallo, Linda C

    2016-01-01

    The study examined the association of childhood and current economic hardship with anthropometric indices in Hispanic/Latino adults, using data from the HCHS/SOL Socio-cultural ancillary study (N = 5,084), a community-based study of Hispanic/Latinos living in four urban areas (Bronx, NY, Chicago, IL, Miami, FL, and San Diego, CA). Childhood economic hardship was defined as having experienced a period of time when one's family had trouble paying for basic needs (e.g., food, housing), and when this economic hardship occurred: between 0-12, 13-18 years old, or throughout both of those times. Current economic hardship was defined as experiencing trouble paying for basic needs during the past 12 months. Anthropometry included height, body mass index (BMI), waist circumference (WC), and percentage body fat (%BF). Complex survey linear regression models were used to test the associations of childhood economic hardship with adult anthropometric indices, adjusting for potential confounders (e.g., age, sex, Hispanic background). Childhood economic hardship varied by Hispanic background, place of birth, and adult socio-economic status. Childhood economic hardship during both periods, childhood and adolescence, was associated with shorter height. Childhood economic hardship was associated with greater adiposity among US born individuals only. Current economic hardship was significantly associated with all three measures of adiposity (BMI, WC, %BF). These findings suggest that previous periods of childhood economic hardship appear to influence adult height more than adiposity, whereas current economic hardship may be a better determinant of adult adiposity in Hispanics. PMID:26919283

  17. Association of Childhood Economic Hardship with Adult Height and Adult Adiposity among Hispanics/Latinos. The HCHS/SOL Socio-Cultural Ancillary Study

    PubMed Central

    Isasi, Carmen R.; Jung, Molly; Parrinello, Christina M.; Kaplan, Robert C.; Kim, Ryung; Crespo, Noe C.; Gonzalez, Patricia; Gouskova, Natalia A.; Penedo, Frank J.; Perreira, Krista M.; Perrino, Tatiana; Sotres-Alvarez, Daniela; Van Horn, Linda; Gallo, Linda C.

    2016-01-01

    The study examined the association of childhood and current economic hardship with anthropometric indices in Hispanic/Latino adults, using data from the HCHS/SOL Socio-cultural ancillary study (N = 5,084), a community-based study of Hispanic/Latinos living in four urban areas (Bronx, NY, Chicago, IL, Miami, FL, and San Diego, CA). Childhood economic hardship was defined as having experienced a period of time when one’s family had trouble paying for basic needs (e.g., food, housing), and when this economic hardship occurred: between 0–12, 13–18 years old, or throughout both of those times. Current economic hardship was defined as experiencing trouble paying for basic needs during the past 12 months. Anthropometry included height, body mass index (BMI), waist circumference (WC), and percentage body fat (%BF). Complex survey linear regression models were used to test the associations of childhood economic hardship with adult anthropometric indices, adjusting for potential confounders (e.g., age, sex, Hispanic background). Childhood economic hardship varied by Hispanic background, place of birth, and adult socio-economic status. Childhood economic hardship during both periods, childhood and adolescence, was associated with shorter height. Childhood economic hardship was associated with greater adiposity among US born individuals only. Current economic hardship was significantly associated with all three measures of adiposity (BMI, WC, %BF). These findings suggest that previous periods of childhood economic hardship appear to influence adult height more than adiposity, whereas current economic hardship may be a better determinant of adult adiposity in Hispanics. PMID:26919283

  18. Donor Age and Corneal Endothelial Cell Loss 5 Years after Successful Corneal Transplantation: Specular Microscopy Ancillary Study Results

    PubMed Central

    2010-01-01

    Objective To determine whether endothelial cell loss 5 years after successful corneal transplantation is related to the age of the donor. Design Multicenter, prospective, double-masked clinical trial. Participants Three hundred forty-seven subjects participating in the Cornea Donor Study who had not experienced graft failure 5 years after corneal transplantation for a moderate-risk condition (principally Fuchs’ dystrophy or pseudophakic corneal edema). Testing Specular microscopic images of donor corneas obtained before surgery and postoperatively at 6 months, 12 months, and then annually through 5 years were submitted to a central reading center to measure endothelial cell density (ECD). Main Outcome Measure Endothelial cell density at 5 years. Results At 5 years, there was a substantial decrease in ECD from baseline for all donor ages. Subjects who received a cornea from a donor 12 to 65 years old experienced a median cell loss of 69% in the study eye, resulting in a 5-year median ECD of 824 cells/mm2 (interquartile range, 613–1342), whereas subjects who received a cornea from a donor 66 to 75 years old experienced a cell loss of 75%, resulting in a median 5-year ECD of 654 cells/mm2 (interquartile range, 538–986) (P [adjusted for baseline ECD] = 0.04). Statistically, there was a weak negative association between ECD and donor age analyzed as a continuous variable (r [adjusted for baseline ECD] = −0.19; 95% confidence interval, −0.29 to −0.08). Conclusions Endothelial cell loss is substantial in the 5 years after corneal transplantation. There is a slight association between cell loss and donor age. This finding emphasizes the importance of longer-term follow-up of this cohort to determine if this relationship affects graft survival. PMID:18387408

  19. Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS)

    PubMed Central

    Crume, Tessa L.; Crandell, Jamie; Norris, Jill M.; Dabelea, Dana; Fangman, Mary T.; Pettitt, David J.; Dolan, Lawrence; Rodriguez, Beatriz L.; O'Connor, Rebecca; Mayer-Davis, Elizabeth J.

    2015-01-01

    The association between timing of complementary food introduction and age at diagnosis of type 1 diabetes was investigated among 1077 children in the SEARCH for Diabetes in Youth study. Age at diagnosis was 5-month earlier for children introduced to sugar-sweetened beverages (SSB) in the first 12 months of life compared to those who were not (9.0 ± 0.2 vs. 9.5 ± 0.1; p=0.02), independent of HLA-risk status. Analyses stratified by HLA-risk status found that children with a high risk HLA genotype had an earlier age at diagnosis if they were introduced to fruit juice in the first year of life (mean age of diagnosis=9.3 ± 0.1, 9.1 ± 0.1 and 9.6 ± 0.2 for introduction at ≤ 6 months, between 7 and 11 months, and ≤12 months, respectively; p=0.04). Introduction of SSB in the first year of life may accelerate onset of type 1 diabetes independent of HLA-risk status. PMID:25117987

  20. Timing of complementary food introduction and age at diagnosis of type 1 diabetes: the SEARCH nutrition ancillary study (SNAS).

    PubMed

    Crume, T L; Crandell, J; Norris, J M; Dabelea, D; Fangman, M T; Pettitt, D J; Dolan, L; Rodriguez, B L; O'Connor, R; Mayer-Davis, E J

    2014-11-01

    The association between timing of complementary food introduction and age at diagnosis of type 1 diabetes was investigated among 1077 children in the SEARCH for Diabetes in Youth study. Age at diagnosis was 5 months earlier for children introduced to sugar-sweetened beverages (SSB) in the first 12 months of life compared with those who were not (9.0±0.2 vs 9.5±0.1; P=0.02) independent of human leukocyte antigen (HLA) risk status. Analyses stratified by HLA risk status found that children with a high-risk HLA genotype had an earlier age at diagnosis if they were introduced to fruit juice in the first year of life (mean age at diagnosis=9.3±0.1, 9.1±0.1 and 9.6±0.2 for introduction at ⩽6 months, between 7 and 11 months and ⩾12 months, respectively; P=0.04). Introduction of SSB in the first year of life may accelerate the onset of type 1 diabetes independent of HLA risk status. PMID:25117987

  1. Cardiovascular Phenotype in Patients with Heart Failure and Preserved Ejection Fraction with or without Diabetes: A RELAX Trial Ancillary Study

    PubMed Central

    Lindman, Brian R.; Dávila-Román, Victor G.; Mann, Douglas L.; McNulty, Steven; Semigran, Marc J.; Lewis, Gregory D.; de las Fuentes, Lisa; Joseph, Susan M.; Vader, Justin; Hernandez, Adrian F.; Redfield, Margaret M.

    2014-01-01

    Background RELAX was a multicenter randomized trial of sildenafil versus placebo in heart failure and preserved ejection fraction (HFpEF) with rigorous entry criteria and extensive phenotypic characterization of participants. Objectives To characterize clinical features, exercise capacity, and outcomes in patients with HFpEF with or without diabetes and gain insight into contributing pathophysiologic mechanisms. Methods RELAX enrolled 216 stable outpatients with heart failure, EF ≥50%, elevated natriuretic peptide or intracardiac pressures, and reduced exercise capacity. Prospectively collected data included echocardiography, cardiac magnetic resonance imaging, a comprehensive biomarker panel, exercise testing, and clinical events over 6 months. Results Compared with non-diabetics (n=123), diabetic (n=93) HFpEF patients were younger, more obese, more often male, and had a higher prevalence of hypertension, renal dysfunction, pulmonary disease, and vascular disease (p<0.05 for all). Uric acid, C-reactive protein, galectin-3, carboxy-terminal telopeptide of collagen type I, and endothelin-1 levels were higher in diabetics (p<0.05 for all). Diabetic patients had more ventricular hypertrophy but systolic and diastolic ventricular function parameters were similar in diabetics and non-diabetics except for a trend toward higher filling pressures (E/e′) in diabetics. Diabetics had worse maximal (peak oxygen uptake) and submaximal (6-minute walk distance) exercise capacity (p<0.01 for both). Diabetic patients were more likely to have been hospitalized for HF in the year prior to study entry (47% vs 28%, p=0.004) and had a higher incidence of cardiac or renal hospitalization at 6 months after enrollment (23.7% vs 4.9%, p<0.001). Conclusions HFpEF patients with diabetes are at increased risk of hospitalization and have reduced exercise capacity. Multi-morbidity, impaired chronotropic reserve, left ventricular hypertrophy and activation of inflammatory, pro

  2. Ancillary Services Provided from DER

    SciTech Connect

    Campbell, J.B.

    2005-12-21

    Distributed energy resources (DER) are quickly making their way to industry primarily as backup generation. They are effective at starting and then producing full-load power within a few seconds. The distribution system is aging and transmission system development has not kept up with the growth in load and generation. The nation's transmission system is stressed with heavy power flows over long distances, and many areas are experiencing problems in providing the power quality needed to satisfy customers. Thus, a new market for DER is beginning to emerge. DER can alleviate the burden on the distribution system by providing ancillary services while providing a cost adjustment for the DER owner. This report describes 10 types of ancillary services that distributed generation (DG) can provide to the distribution system. Of these 10 services the feasibility, control strategy, effectiveness, and cost benefits are all analyzed as in the context of a future utility-power market. In this market, services will be provided at a local level that will benefit the customer, the distribution utility, and the transmission company.

  3. Medical Researchers' Ancillary Care Obligations: The Relationship-Based Approach.

    PubMed

    Olson, Nate W

    2016-06-01

    In this article, I provide a new account of the basis of medical researchers' ancillary care obligations. Ancillary care in medical research, or medical care that research participants need but that is not required for the validity or safety of a study or to redress research injuries, is a topic that has drawn increasing attention in research ethics over the last ten years. My view, the relationship-based approach, improves on the main existing theory, Richardson and Belsky's 'partial-entrustment model', by avoiding its problematic restriction on the scope of health needs for which researchers could be obligated to provide ancillary care. Instead, it grounds ancillary care obligations in a wide range of morally relevant features of the researcher-participant relationship, including the level of engagement between researchers and participants, and weighs these factors against each other. I argue that the level of engagement, that is, the duration and intensity of interactions, between researchers and participants matters for ancillary care because of its connection to the meaningfulness of a relationship, and I suggest that other morally relevant features can be grounded in researchers' role obligations. PMID:26424512

  4. Loads Providing Ancillary Services: Review of International Experience

    SciTech Connect

    Heffner, Grayson; Goldman, Charles; Kintner-Meyer, Michael

    2007-05-01

    In this study, we examine the arrangements for and experiences of end-use loads providing ancillary services (AS) in five electricity markets: Australia, the United Kingdom (UK), the Nordic market, and the ERCOT and PJM markets in the United States. Our objective in undertaking this review of international experience was to identify specific approaches or market designs that have enabled customer loads to effectively deliver various ancillary services (AS) products. We hope that this report will contribute to the ongoing discussion in the U.S. and elsewhere regarding what institutional and technical developments are needed to ensure that customer loads can meaningfully participate in all wholesale electricity markets.

  5. The Role of Stress in Understanding Differences in Sedentary Behavior in Hispanic/Latino Adults: Results From the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study

    PubMed Central

    Vásquez, Elizabeth; Strizich, Garrett; Gallo, Linda; Marshall, Simon J.; Merchant, Gina C.; Murillo, Rosenda; Penedo, Frank J.; Salazar, Christian; Sotres-Alvarez, Daniela; Shaw, Benjamin A.; Isasi, Carmen R.

    2016-01-01

    Background Chronic stress and/or lifetime traumatic stress can create a self-reinforcing cycle of unhealthy behaviors, such as overeating and sedentary behavior, that can lead to further increases in stress. This study examined the relationship between stress and sedentary behavior in a sample of Hispanic/Latino adults (N = 4244) from the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study. Methods Stress was measured as the number of ongoing difficulties lasting 6 months or more and as lifetime exposure to traumatic events. Sedentary behavior was measured by self-report and with accelerometer. Multivariable regression models examined associations of stress measures with time spent in sedentary behaviors adjusting by potential confounders. Results Those who reported more than one chronic stressor spent, on average, 8 to 10 additional minutes per day in objectively measured sedentary activities (P < .05), whereas those with more than one lifetime traumatic stressor spent (after we adjusted for confounders) 10 to 14 additional minutes in sedentary activities (P < .01) compared with those who did not report any stressors. Statistical interactions between the 2 stress measures and age or sex were not significant. Conclusion Interventions aimed at reducing sedentary behaviors might consider incorporating stress reduction into their approaches. PMID:26181079

  6. Comparison of Self-Reported Sleep Duration With Actigraphy: Results From the Hispanic Community Health Study/Study of Latinos Sueño Ancillary Study.

    PubMed

    Cespedes, Elizabeth M; Hu, Frank B; Redline, Susan; Rosner, Bernard; Alcantara, Carmela; Cai, Jianwen; Hall, Martica H; Loredo, Jose S; Mossavar-Rahmani, Yasmin; Ramos, Alberto R; Reid, Kathryn J; Shah, Neomi A; Sotres-Alvarez, Daniela; Zee, Phyllis C; Wang, Rui; Patel, Sanjay R

    2016-03-15

    Most studies of sleep and health outcomes rely on self-reported sleep duration, although correlation with objective measures is poor. In this study, we defined sociodemographic and sleep characteristics associated with misreporting and assessed whether accounting for these factors better explains variation in objective sleep duration among 2,086 participants in the Hispanic Community Health Study/Study of Latinos who completed more than 5 nights of wrist actigraphy and reported habitual bed/wake times from 2010 to 2013. Using linear regression, we examined self-report as a predictor of actigraphy-assessed sleep duration. Mean amount of time spent asleep was 7.85 (standard deviation, 1.12) hours by self-report and 6.74 (standard deviation, 1.02) hours by actigraphy; correlation between them was 0.43. For each additional hour of self-reported sleep, actigraphy time spent asleep increased by 20 minutes (95% confidence interval: 19, 22). Correlations between self-reported and actigraphy-assessed time spent asleep were lower with male sex, younger age, sleep efficiency <85%, and night-to-night variability in sleep duration ≥1.5 hours. Adding sociodemographic and sleep factors to self-reports increased the proportion of variance explained in actigraphy-assessed sleep slightly (18%-32%). In this large validation study including Hispanics/Latinos, we demonstrated a moderate correlation between self-reported and actigraphy-assessed time spent asleep. The performance of self-reports varied by demographic and sleep measures but not by Hispanic subgroup. PMID:26940117

  7. Legal issues affecting ancillaries and orthopedic practice.

    PubMed

    Glaser, David M

    2008-01-01

    The federal and state governments have imposed significant regulations on health care generally and on ancillary services in particular. This article focuses on how state and federal laws shape the ability of an orthopedic physician to offer ancillary services, whether as an individual, through a group practice, or as part of a joint venture. It focuses on how the Stark law, the Medicare anti-kickback statute, state anti-kickback, fee-splitting provisions, certificate of need laws, and various Medicare billing and supervision requirements impact the provision of ancillary services. It also briefly discusses how physicians should prepare for and respond to government investigations. PMID:18061773

  8. 78 FR 41941 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ... Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as... Kidney Diseases Special Emphasis Panel; PAR12-265 Ancillary Studies in Kidney Disease and Complications... Institute of Diabetes and Digestive and Kidney Diseases Special, Emphasis Panel; CRIC Ancillary...

  9. Model-Based Estimation of Forest Canopy Height in Red and Austrian Pine Stands Using Shuttle Radar Topography Mission and Ancillary Data: a Proof-of-Concept Study

    SciTech Connect

    Brown Jr., C G; Sarabandi, K; Pierce, L E

    2007-04-06

    In this paper, accurate tree stand height retrieval is demonstrated using C-band Shuttle Radar Topography Mission (SRTM) height and ancillary data. The tree height retrieval algorithm is based on modeling uniform tree stands with a single layer of randomly oriented vegetation particles. For such scattering media, the scattering phase center height, as measured by SRTM, is a function of tree height, incidence angle, and the extinction coefficient of the medium. The extinction coefficient for uniform tree stands is calculated as a function of tree height and density using allometric equations and a fractal tree model. The accuracy of the proposed algorithm is demonstrated using SRTM and TOPSAR data for 15 red pine and Austrian pine stands (TOPSAR is an airborne interferometric synthetic aperture radar). The algorithm yields root-mean-square (rms) errors of 2.5-3.6 m, which is a substantial improvement over the 6.8-8.3-m rms errors from the raw SRTM minus National Elevation Dataset Heights.

  10. Reconsidering the measurement of ancillary service performance.

    PubMed

    Griffin, D T; Rauscher, J A

    1987-08-01

    Prospective payment reimbursement systems have forced hospitals to review their costs more carefully. The result of the increased emphasis on costs is that many hospitals use costs, rather than margin, to judge the performance of ancillary services. However, arbitrary selection of performance measures for ancillary services can result in managerial decisions contrary to hospital objectives. Managerial accounting systems provide models which assist in the development of performance measures for ancillary services. Selection of appropriate performance measures provides managers with the incentive to pursue goals congruent with those of the hospital overall. This article reviews the design and implementation of managerial accounting systems, and considers the impact of prospective payment systems and proposed changes in capital reimbursement on this process. PMID:10317937

  11. 30 CFR 250.207 - What ancillary activities may I conduct?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Ancillary... surveys; or (c) Studies that model potential oil and hazardous substance spills, drilling muds...

  12. Physician variations and the ancillary costs of neonatal intensive care.

    PubMed Central

    Perlstein, P H; Atherton, H D; Donovan, E F; Richardson, D K; Kotagal, U R

    1997-01-01

    OBJECTIVE: To determine to what degree attending physicians contribute to cost variations in the care of ventilator-dependent newborns. DATA SOURCES: Clinical data were merged with hospital financial data describing daily ancillary care costs during the first two weeks of life for 132 extremely low-birthweight newborns. In addition, each patient's chart was reviewed and illness severity graded using both SNAP and CRIB scores. STUDY DESIGN: This was a retrospective cohort of infants with birth weights of less than 1,001 grams and respiratory distress syndrome requiring mechanical ventilation in the first day of life. From birth up to two weeks of life, each received care directed by only one of 11 faculty neonatologists in a single university hospital. Data were analyzed stratified by these physicians. t-Test, ANOVA, and chi-square were used to assess bivariate data. For continuous data, log linear regressions were used. PRINCIPAL FINDINGS: After controlling for illness severity, when stratified by physicians, there were significant variances in the costs of ancillary resources for the study infants (p < .0001). Twenty-nine percent of the variance was attributable to whether or not the hospital day included the use of a ventilator. Physician identity explained only 5.6 percent (p < .0001). CONCLUSIONS: Physician identity was significant but explained less than 6 percent of the total variance in ancillary costs. Whether or not a ventilator was used during care was far more important. We conclude that for very sick babies during the first two weeks of care, reducing variations in ancillary services utilization among neonatologists will yield only modest savings. PMID:9240282

  13. 18 CFR 35.40 - Ancillary services.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....40 Section 35.40 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT FILING OF RATE SCHEDULES AND TARIFFS Wholesale Sales of Electric Energy, Capacity and Ancillary Services at Market-Based Rates § 35.40...

  14. Optimal generator bidding strategies for power and ancillary services

    NASA Astrophysics Data System (ADS)

    Morinec, Allen G.

    As the electric power industry transitions to a deregulated market, power transactions are made upon price rather than cost. Generator companies are interested in maximizing their profits rather than overall system efficiency. A method to equitably compensate generation providers for real power, and ancillary services such as reactive power and spinning reserve, will ensure a competitive market with an adequate number of suppliers. Optimizing the generation product mix during bidding is necessary to maximize a generator company's profits. The objective of this research work is to determine and formulate appropriate optimal bidding strategies for a generation company in both the energy and ancillary services markets. These strategies should incorporate the capability curves of their generators as constraints to define the optimal product mix and price offered in the day-ahead and real time spot markets. In order to achieve such a goal, a two-player model was composed to simulate market auctions for power generation. A dynamic game methodology was developed to identify Nash Equilibria and Mixed-Strategy Nash Equilibria solutions as optimal generation bidding strategies for two-player non-cooperative variable-sum matrix games with incomplete information. These games integrated the generation product mix of real power, reactive power, and spinning reserve with the generators's capability curves as constraints. The research includes simulations of market auctions, where strategies were tested for generators with different unit constraints, costs, types of competitors, strategies, and demand levels. Studies on the capability of large hydrogen cooled synchronous generators were utilized to derive useful equations that define the exact shape of the capability curve from the intersections of the arcs defined by the centers and radial vectors of the rotor, stator, and steady-state stability limits. The available reactive reserve and spinning reserve were calculated given a

  15. Ocular screening adherence across Hispanic/Latino heritage groups with diabetes: results from the Ocular SOL ancillary to the Miami site of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

    PubMed Central

    Tannenbaum, Stacey L; McClure, Laura A; Zheng, D Diane; Lam, Byron L; Arheart, Kristopher L; Joslin, Charlotte E; Talavera, Gregory A; Lee, David J

    2016-01-01

    Objective The objective of this study was to examine the prevalence and correlates of ocular screening adherence among select Hispanics/Latinos living with diabetes. Research design and methods Data were obtained through an ancillary study of the Hispanic Community Health Study/Study of Latinos (Miami site). Participants included Hispanics/Latinos aged 40+ years who underwent a baseline examination/risk factor assessment (2008–2011) and then completed a survey on vision health/knowledge (conducted October 2011–September 2013; sample n=1235; diabetic subsample=264). The dependent variable was having a dilated eye examination within the past 12 months. Covariate candidate selection for entry into sequential multivariable logistic regression models was guided by Anderson's Behavioral Model of Health Services Use and the Behavioral Model for Vulnerable Populations. Results Participants aged 65+ were more likely to have dilated eye examinations (OR 2.62, 95% CI 1.22 to 5.60) compared with those aged 40–54 years. Participants less likely to have dilated examinations had a high school degree or general educational development (GED) (OR 0.30, 95% CI 0.10 to 0.96, compared to no degree) and those currently uninsured or never insured ((OR 0.34, 95% CI 0.14 to 0.83) and (OR 0.19, 95% CI 0.07 to 0.51)) compared to those currently insured. Participants who heard or saw something about eye health from two or more sources (eg, media outlets, doctor's office, relatives/friends) compared to those who reported no sources in the past 12 months were more likely to have a dilated eye examination (OR 2.82, 95% CI 1.26 to 6.28). Conclusions Lack of health insurance is strongly associated with low screening uptake in Hispanics/Latinos living with diabetes. Health promotion strategies stressing the importance of annual dilated eye examinations and increasing sources of information on eye health are other potential strategies to increase screening uptake in Hispanics

  16. SKIN WRINKLES AND RIGIDITY IN EARLY POSTMENOPAUSAL WOMEN VARY BY RACE/ETHNICITY: BASELINE CHARACTERISTICS OF THE SKIN ANCILLARY STUDY OF THE KEEPS TRIAL

    PubMed Central

    Wolff, Erin; Pal, Lubna; Altun, Tugba; Madankumar, Rajeevi; Freeman, Ruth; Amin, Hussein; Harman, Mitch; Santoro, Nanette; Taylor, Hugh S.

    2010-01-01

    Objective To characterize skin wrinkles and rigidity in recently menopausal women. Design Baseline assessment of participants prior to randomization to study drug. Setting Multicenter trial, university medical centers. Patients Recently menopausal participants enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). Interventions Skin wrinkles were assessed at 11 locations on the face and neck using the Lemperle wrinkle scale. Skin rigidity was assessed at the forehead and cheek using a durometer. Outcome Skin wrinkles and rigidity were compared among race/ethnic groups. Skin wrinkles and rigidity were correlated with age, time since menopause, weight, and BMI. Results In early menopausal women, wrinkles, but not skin rigidity, vary significantly among races (p=0.0003), where Black women have the lowest wrinkle scores. In White women, chronological age was significantly correlated with worsening skin wrinkles, but not with rigidity(p<0.001). Skin rigidity correlated with increasing length of time since menopause, however only in the White subgroup (p<0.01). In the combined study group, increasing weight was associated with less skin wrinkling (p<0.05). Conclusions Skin characteristics of recently menopausal women are not well studied. Ethnic differences in skin characteristics are widely accepted, but poorly described. In recently menopausal women not using hormone therapy (HT), significant racial differences in skin wrinkling and rigidity exist. Continued study of the KEEPS population will provide evidence of the effects of HT on the skin aging process in early menopausal women. PMID:20971461

  17. Perspective: A Critical Look at the Ancillary Age-Related Eye Disease Study 2: Nutrition and Cognitive Function Results in Older Individuals with Age-Related Macular Degeneration.

    PubMed

    Hammond, Billy R; Renzi-Hammond, Lisa M

    2016-05-01

    A large body of literature suggests that the dietary carotenoids lutein and zeaxanthin and long-chain polyunsaturated fatty acids such as docosahexaenoic acid are related to improved cognitive function across the life span. A recent report by the Age-Related Eye Disease Study (AREDS) group appears to contradict the general findings of others in the field. In this review, we look critically at the methods, study designs, and analysis techniques used in the larger body of literature and compare them with the recent AREDS reports. PMID:27184270

  18. ProEx™ C is a useful ancillary study for grading anal intraepithelial neoplasia alone and in combination with other biomarkers.

    PubMed

    Larson, Brent K; Mohanty, Sambit K; Wu, Julie M; Bose, Shikha; Walts, Ann E

    2016-03-01

    Anal intraepithelial neoplasia (AIN) is a precursor to invasive anal squamous cell carcinoma. Histologic evaluation is hampered by intra- and interobserver variability. Various biomarkers have been investigated to improve the accuracy and reproducibility of diagnosis and grading, but interpretation can be challenging. ProEx™ C is an antibody cocktail for proteins upregulated in cervical intraepithelial neoplasia. This study investigated ProEx™ C's role alone and with p16 and Ki-67 in the diagnosis and grading of AIN. Sixty-seven anal tissue samples (22 AIN I, 25 AIN II/III, and 20 non-dysplastic) were stained for ProEx™ C, Ki-67, and p16. Staining patterns were recorded and correlated with morphologic diagnoses. Considering AIN II/III vs I, full-thickness ProEx™ C staining was more frequent in AIN II/III (p = 0.0373), and showed the highest sensitivity of the biomarkers. In combination with Ki-67, sensitivity was lower, but specificity for AIN II/III rose to 83%. For differentiating non-dysplasia from AIN I, negative ProEx™ C staining correlated with non-dysplasia (p < 0.0001) and had the highest sensitivity (90%). In combination with Ki-67, sensitivity dropped to 80%, but specificity was high (96%). ProEx™ C is useful for diagnosing and grading AIN, performing as well or better than other markers at identifying AIN II/III and non-dysplastic epithelium. PMID:26590011

  19. Women's Health Initiative diet intervention did not increase macular pigment optical density in an ancillary study of a subsample of the Women's Health Initiative.

    PubMed

    Moeller, Suzen M; Voland, Rick; Sarto, Gloria E; Gobel, Vicki L; Streicher, Sharyn L; Mares, Julie A

    2009-09-01

    In this study, we examined the impact of long-term (>8 y), low-fat, high-fruit and -vegetable diets on levels of lutein and zeaxanthin in the macula of the retina, as indicated by the OD of macular pigment. Macular pigment OD, measured by heterochromatic flicker photometry, was compared in women aged 60-87 y, who, 7-18 mo earlier (median 12 mo), had been in the dietary modification intervention (n = 158) or comparison (n = 236) groups of the Women's Health Initiative (WHI) at the Madison, WI site for a mean of 8.5 y. Women in the intervention group ate more fruits and vegetables (mean +/- SEM) (6.1 +/- 0.2 vs. 4.6 +/- 0.2 servings/d; P < 0.0001) and had higher intakes of lutein and zeaxanthin from foods and supplements (2.7 +/- 0.2 vs. 2.1 +/- 0.1 mg/d; P = 0.0003) than the comparison group. However, macular pigment density did not differ between the intervention (0.36 +/- 0.02 OD units) and comparison (0.35 +/- 0.01 OD units) groups. It tended to be higher (11%; P = 0.11) in women consuming lutein and zeaxanthin in the highest compared with the lowest quintile (median 6.4 vs. 1.1 mg/d). The increase in fruit and vegetable intake among dietary modification participants of this WHI subsample was not of sufficient magnitude to alter the mean density of retinal carotenoids, given other existing dietary conditions in this sample. PMID:19587126

  20. Agreement of single- and multi-frequency Bioimpedance Measurements in hemodialysis patients: An Ancillary Study of the Frequent Hemodialysis Network (FHN) Daily Trial

    PubMed Central

    Raimann, Jochen G.; Abbas, Samer R.; Liu, Li; Zhu, Fansan; Larive, Brett; Kotanko, Peter; Levin, Nathan W.; Kaysen, George A.

    2015-01-01

    Background Bioimpedance analysis (BIA) is well established to assess body composition. Agreements between single- and multi-frequency bioimpedance (SF-BIA, MF-BIS) assessments in subjects undergoing 6 or 3 times per week hemodialysis (HD) were analyzed. Methods Total body water (TBW), intra- and extracellular fluid (ICF, ECF) of subjects enrolled in the Frequent Hemodialysis Network (FHN) Daily Trial (www.clinicaltrials.gov # NCT00264758) were measured with a Hydra 4200 at baseline (BL) and at 5 months (M5). Volumes were computed using SF (at 50 kHz) and MF approaches. Agreement was assessed by means of Linear Regression and Bland-Altman analysis and treatment effects by T-Test. Results 35 subjects (17 on the more frequent regimen, 26 male, 20 blacks, 48±9 years, pre-HD weight 84±19 kg) were studied. Assessments with SF-BIA and MF-BIS correlated significantly at BL and M5 in both arms. No proportional errors, but systematic biases over the entire range of values were found at BL and M5. Agreement did not differ between subjects randomized to either HD treatment arm at both time points. MF-BIS appears to have better precision than SF-BIA allowing the observation of a significant treatment effect by the intervention [−1.5 (95% CI −2.5 to −0.5) L] on ECF, not found for ECF SF-BIA. Precision also affected the statistical power of the SF-BIA data in the current analysis. Conclusion Both methods showed agreement without significant proportional errors regardless of HD frequency and can be used for longitudinal analyses. SF-BIA has lower precision which needs thorough consideration in the design of future trials with similar outcomes. PMID:25402657

  1. Sexual relationships outside primary partnerships and abstinence are associated with lower adherence and adherence gaps: data from the Partners PrEP Ancillary Adherence Study

    PubMed Central

    Kintu, Alexander; Hankinson, Susan E.; Balasubramanian, Raji; Ertel, Karen; Tumwesigye, Elioda; Bangsberg, David R.; Haberer, Jessica E.

    2015-01-01

    Objective To assess the role of sexual relationships on levels and patterns of adherence to medication for pre-exposure prophylaxis (PrEP) against HIV. Methods We enrolled 1,147 HIV-negative individuals in long-term serodiscordant relationships at three sites in Uganda from the Partners PrEP Study- a randomized placebo-controlled trial of daily oral tenofovir and emtricitabine/tenofovir. We used generalized estimation equations to assess the effects of sexual relationships on low adherence (<80%) and on gaps in adherence. Results Fifty-three percent were male, 51% were 18-34 years and 24% were polygamous. Participants who reported sex in the past month with someone other than their primary partner and with <100% condom use were more than twice as likely to have low adherence (aOR 2.48, 95% CI: 1.70-3.62) compared to those who had sex with only their primary partners and 100% condom use. Using the same reference group, those who abstained from sex in the previous month had 30% increased odds of low adherence (aOR 1.30, 95% CI: 1.05-1.62), and participants in non-polygamous marriages who reported sex with both their primary and other partners and <100% condom use were almost twice as likely to be low adherers (aOR 1.76, 95% CI: 1.01-3.08). At least one 72-hour gap in adherence was seen in 598 participants (54.7%); 23.2% had at least one one-week gap. Conclusions Risk of low overall adherence was higher in participants who reported sex outside primary partnerships and suboptimal condom use, as well as in those who abstained from sex. Adherence gaps were common, potentially creating risk for HIV acquisition. PMID:25942457

  2. Increasing productivity in dental practice: the role of ancillary personnel.

    PubMed

    Guay, Albert H; Lazar, Vickie

    2012-01-01

    Dentistry has achieved substantial improvements in productivity which have the effect of making more care available at reasonable cost. Data are presented documenting trends in productivity. These are analyzed with respect to number of dentists, hours worked by dentists, and the use of ancillary personal in dental offices. There is strong evidence linking increased productivity to the use of ancillary personnel. The history of creation, recognition, and integration of ancillary personnel into dental practice is also presented. PMID:22856048

  3. Loads Providing Ancillary Services: Review of InternationalExperience-- Technical Appendix: Market Descriptions

    SciTech Connect

    Grayson Heffner, Charles Goldman, Kintner-Meyer, M; Kirby, Brendan

    2007-05-01

    In this study, we examine the arrangements for andexperiences of end-use loads providing ancillary services (AS) in fiveelectricity markets: Australia, the United Kingdom (UK), the Nordicmarket, and the ERCOT and PJM markets in the United States. Our objectivein undertaking this review of international experience was to identifyspecific approaches or market designs that have enabled customer loads toeffectively deliver various ancillary services (AS) products. We hopethat this report will contribute to the ongoing discussion in the U.S.and elsewhere regarding what institutional and technical developments areneeded to ensure that customer loads can meaningfully participate in allwholesale electricity markets.

  4. 10 CFR 205.288 - Interim and ancillary orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Interim and ancillary orders. 205.288 Section 205.288 Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS Special Procedures for Distribution of Refunds § 205.288 Interim and ancillary orders. The Director of the Office of Hearings...

  5. 1 CFR 10.12 - Format, indexes, and ancillaries.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 General Provisions 1 2012-01-01 2012-01-01 false Format, indexes, and ancillaries. 10.12 Section 10.12 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.12 Format, indexes, and ancillaries. (a)...

  6. 1 CFR 10.12 - Format, indexes, and ancillaries.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Format, indexes, and ancillaries. 10.12 Section 10.12 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.12 Format, indexes, and ancillaries. (a)...

  7. 1 CFR 10.12 - Format, indexes, and ancillaries.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Format, indexes, and ancillaries. 10.12 Section 10.12 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.12 Format, indexes, and ancillaries. (a)...

  8. 1 CFR 10.12 - Format, indexes, and ancillaries.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 General Provisions 1 2013-01-01 2012-01-01 true Format, indexes, and ancillaries. 10.12 Section 10.12 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.12 Format, indexes, and ancillaries. (a)...

  9. 1 CFR 10.12 - Format, indexes, and ancillaries.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 General Provisions 1 2014-01-01 2012-01-01 true Format, indexes, and ancillaries. 10.12 Section 10.12 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER SPECIAL EDITIONS OF THE FEDERAL REGISTER PRESIDENTIAL PAPERS Annual Publication § 10.12 Format, indexes, and ancillaries. (a)...

  10. An integrated LANDSAT/ancillary data classification of desert rangeland

    NASA Technical Reports Server (NTRS)

    Price, K. P.; Ridd, M. K.; Merola, J. A.

    1984-01-01

    Range inventorying methods using LANDSAT MSS data, coupled with ancillary data were examined. The study area encompassed nearly 20,000 acres in Rush Valley, Utah. The vegetation is predominately desert shrub and annual grasses, with some annual forbs. Three LANDSAT scenes were evaluated using a Kauth-Thomas brightness/greenness data transformation (May, June, and August dates). The data was classified using a four-band maximum-likelihood classifier. A print map was taken into the field to determine the relationship between print symbols and vegetation. It was determined that classification confusion could be greatly reduced by incorporating geomorphic units and soil texture (coarse vs fine) into the classification. Spectral data, geomorphic units, and soil texture were combined in a GIS format to produce a final vegetation map identifying 12 vegetation types.

  11. Comparing Patients’ Opinions on the Hospital Discharge Process Collected With a Self-Reported Questionnaire Completed Via the Internet or Through a Telephone Survey: An Ancillary Study of the SENTIPAT Randomized Controlled Trial

    PubMed Central

    Carrat, Fabrice; Hejblum, Gilles

    2015-01-01

    Background Hospital discharge, a critical stage in the hospital-to-home transition of patient care, is a complex process with potential dysfunctions having an impact on patients’ health on their return home. No study has yet reported the feasibility and usefulness of an information system that would directly collect and transmit, via the Internet, volunteer patients’ opinions on their satisfaction concerning the organization of hospital discharge. Objective Our primary objective was to compare patients’ opinions on the discharge process collected with 2 different methods: self-questionnaire completed on a dedicated website versus a telephone interview. The secondary goal was to estimate patient satisfaction. Methods We created a questionnaire to examine hospital discharge according to 3 dimensions: discharge logistics organization, preplanned posthospital continuity-of-care organization, and patients’ impressions at the time of discharge. A satisfaction score (between 0 and 1) for each of those dimensions and an associated total score were calculated. Taking advantage of the randomized SENTIPAT trial that questioned patients recruited at hospital discharge about the evolution of their health after returning home and randomly assigned them to complete a self-questionnaire directly online or during a telephone interview, we conducted an ancillary study comparing satisfaction with the organization of hospital discharge for these 2 patient groups. The questionnaire was proposed to 1141 patients included in the trial who were hospitalized for ≥2 days, among whom 867 eligible patients had access to the Internet at home and were randomized to the Internet or telephone group. Results Of the 1141 patients included, 755 (66.17%) completed the questionnaire. The response rates for the Internet (39.1%, 168/430) and telephone groups (87.2%, 381/437) differed significantly (P<.001), but their total satisfaction scores did not (P=.08) nor did the satisfaction subscores

  12. Evaluation report: dialysis and ancillary equipment.

    PubMed

    1986-01-01

    As part of the continuing programme of evaluation of medical equipment sponsored by the UK Health Departments, the evaluation of dialysis and ancillary equipment is being carried out within the University of Sheffield, under the direction of Professor M. M. Black. 'Health Equipment Information' Number 148, published in December 1985, carries full reports on the Cobe Centry 2Rx haemodialysis system with double blood pump module (DBPM), the Lucas Medical 2100 haemodialysis system, and the Permutit Series 8 water softener. It also contains summaries of full reports on the Organon-Teknika Sorbsystem and Cordis-Dow Seratron haemodialysis systems, and the Gordonsal RD500 and Elga Mediro D water softeners, which were published in 'HEI' 136. Readers should note that the Cordis Seratron and Lucas 2100 models are no longer available in the UK. Extracts of the evaluations of the Cobe Centry 2Rx + DBPM and the Permutit Series B models, together with summaries and overall comparisons, are given below. 'HEI' (ISSN 0261-0736) is free to NHS staff and 5.00 pounds/copy to others. Editorial enquiries to DHSS Scientific and Technical Branch, 14 Russell Square, London WC1B 5EP. PMID:3735384

  13. ETINDE. Improving the role of a methodological approach and ancillary ethnoarchaeological data application for place vulnerability and resilience to a multi-hazard environment: Mt. Cameroon volcano case study [MIA-VITA project -FP7-ENV-2007-1

    NASA Astrophysics Data System (ADS)

    Ilaria Pannaccione Apa, Maria; Kouokam, Emmanuel; Mbe Akoko, Robert; Peppoloni, Silvia; Fabrizia Buongiorno, Maria; Thierry, Pierre

    2013-04-01

    The FP7 MIA-VITA [Mitigate and assess risk from volcanic impact on terrain and human activities] project has been designed to address multidisciplinary aspects of volcanic threat assessment and management from prevention to crisis management recovery. In the socio-economic analysis carried out at Mt. Cameroon Bakweri and Bakossi ethnic groups, ancillary ethnoarchaeological information has been included to point out the cultural interaction between the volcano and its residents. In 2009-2011, ethnoanthropological surveys and interviews for data collection were carried out at Buea, Limbe, West Coast, Tiko and Muyuka sub-divisions adjacent to Mt. Cameroon. One of the outstanding, results from the Bakweri and Bakossi cultural tradition study: natural hazards are managed and produced by supernatural forces, as: Epasa Moto, God of the Mountain (Mt. Cameroon volcano) and Nyango Na Nwana , Goddess of the sea (Gulf of Guinea). In the case of Mount Cameroon, people may seek the spirit or gods of the mountain before farming, hunting and most recently the undertaking of the Mount Cameroon annual race are done. The spirit of this mountain must be seek to avert or stop a volcanic eruption because the eruption is attributed to the anger of the spirit. Among the Northern Bakweri, the association of spirits with the mountain could also be explained in terms of the importance of the mountain to the people. Most of their farming and hunting is done on the Mountain. Some forest products, for instance, wood for building and furniture is obtained from the forest of the mountain; this implies that the people rely on the Mountain for food, game and architecture/furniture etc. In addition, the eruption of the mountain is something which affects the people. It does not only destroy property, it frustrates people and takes away human lives when it occurs. Because of this economic importance of the Mountain and its unexpected and unwanted eruption, the tendency is to believe that it has some

  14. 1. EXTERIOR VIEW TO THE NORTHWEST OF ANCILLARY STRUCTURES ASSOCIATED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR VIEW TO THE NORTHWEST OF ANCILLARY STRUCTURES ASSOCIATED WITH AND SURROUNDING BUILDING 3210. - Nevada Test Site, Test Cell C Facility, Elevated Water Tower, Area 25, Jackass Flats, Road J, Mercury, Nye County, NV

  15. Load Participation in Ancillary Services System from An Operator Perspective

    SciTech Connect

    Kujawski, Don; Petri, Mark C.

    2011-10-25

    Ancillary services as defined by FERC (Order 888) distinguished by response time, duration, frequency. Met when DR has capability to balance supply and demand; and LMP payment to DR is cost effective.

  16. Level 2 Ancillary Products and Datasets Algorithm Theoretical Basis

    NASA Technical Reports Server (NTRS)

    Diner, D.; Abdou, W.; Gordon, H.; Kahn, R.; Knyazikhin, Y.; Martonchik, J.; McDonald, D.; McMuldroch, S.; Myneni, R.; West, R.

    1999-01-01

    This Algorithm Theoretical Basis (ATB) document describes the algorithms used to generate the parameters of certain ancillary products and datasets used during Level 2 processing of Multi-angle Imaging SpectroRadiometer (MIST) data.

  17. Ancillary Data Services of NASA's Planetary Data System

    NASA Technical Reports Server (NTRS)

    Acton, C.

    1994-01-01

    JPL's Navigation and Ancillary Information Facility (NAIF) has primary responsibility for design and implementation of the SPICE ancillary information system, supporting a wide range of space science mission design, observation planning and data analysis functions/activities. NAIF also serves as the geometry and ancillary data node of the Planetary Data System (PDS). As part of the PDS, NAIF archives SPICE and other ancillary data produced by flight projects. NAIF then distributes these data, and associated data access software and high-level tools, to researchers funded by NASA's Office of Space Science. Support for a broader user community is also offered to the extent resources permit. This paper describes the SPICE system and customer support offered by NAIF.

  18. Ancillary-service details: Dynamic scheduling

    SciTech Connect

    Hirst, E.; Kirby, B.

    1997-01-01

    Dynamic scheduling (DS) is the electronic transfer from one control area to another of the time-varying electricity consumption associated with a load or the time-varying electricity production associated with a generator. Although electric utilities have been using this technique for at least two decades, its use is growing in popularity and importance. This growth is a consequence of the major changes under way in US bulk-power markets, in particular efforts to unbundle generation from transmission and to increase competition among generation providers. DS can promote competition and increase choices. It allows consumers to purchase certain services from entities outside their physical-host area and it allows generators to sell certain services to entities other than their physical host. These services include regulation (following minute-to-minute variations in load) and operating reserves, among others. Such an increase in the number of possible suppliers and customers should encourage innovation and reduce the costs and prices of providing electricity services. The purpose of the project reported here was to collect and analyze data on utility experiences with DS. Chapter 2 provides additional details and examples of the definitions of DS. Chapter 3 explains why DS might be an attractive service that customers and generators, as well as transmission providers, might wan to use. Chapter 4 presents some of the many current DS examples the authors uncovered in their interviews. Chapter 5 discusses the costs and cost-effectiveness of DS. Chapter 6 explains what they believe can and cannot be electronically moved from one control area to another, primarily in terms of the six ancillary services that FERC defined in Order 888. Chapter 7 discusses the need for additional research on DS.

  19. Ancillary human health benefits of improved air quality resulting from climate change mitigation

    PubMed Central

    Bell, Michelle L; Davis, Devra L; Cifuentes, Luis A; Krupnick, Alan J; Morgenstern, Richard D; Thurston, George D

    2008-01-01

    Background Greenhouse gas (GHG) mitigation policies can provide ancillary benefits in terms of short-term improvements in air quality and associated health benefits. Several studies have analyzed the ancillary impacts of GHG policies for a variety of locations, pollutants, and policies. In this paper we review the existing evidence on ancillary health benefits relating to air pollution from various GHG strategies and provide a framework for such analysis. Methods We evaluate techniques used in different stages of such research for estimation of: (1) changes in air pollutant concentrations; (2) avoided adverse health endpoints; and (3) economic valuation of health consequences. The limitations and merits of various methods are examined. Finally, we conclude with recommendations for ancillary benefits analysis and related research gaps in the relevant disciplines. Results We found that to date most assessments have focused their analysis more heavily on one aspect of the framework (e.g., economic analysis). While a wide range of methods was applied to various policies and regions, results from multiple studies provide strong evidence that the short-term public health and economic benefits of ancillary benefits related to GHG mitigation strategies are substantial. Further, results of these analyses are likely to be underestimates because there are a number of important unquantified health and economic endpoints. Conclusion Remaining challenges include integrating the understanding of the relative toxicity of particulate matter by components or sources, developing better estimates of public health and environmental impacts on selected sub-populations, and devising new methods for evaluating heretofore unquantified and non-monetized benefits. PMID:18671873

  20. Survey of U.S. Ancillary Services Markets

    SciTech Connect

    Zhou, Zhi; Levin, Todd; Conzelmann, Guenter

    2016-01-01

    In addition to providing energy to end-consumers, power system operators are also responsible for ensuring system reliability. To this end, power markets maintain an array of ancillary services to ensure it is always possible to balance the supply and demand for energy in real-time. A subset of these ancillary services are commonly procured through market-based mechanisms: namely, Regulation, Spinning, and Non-spinning Reserves.

  1. Influence of Ancillary Ligands in Dye-Sensitized Solar Cells.

    PubMed

    Pashaei, Babak; Shahroosvand, Hashem; Graetzel, Michael; Nazeeruddin, Mohammad Khaja

    2016-08-24

    Dye-sensitized solar cells (DSSCs) have motivated many researchers to develop various sensitizers with tailored properties involving anchoring and ancillary ligands. Ancillary ligands carry favorable light-harvesting abilities and are therefore crucial in determining the overall power conversion efficiencies. The use of ancillary ligands having aliphatic chains and/or π-extended aromatic units decreases charge recombination and permits the collection of a large fraction of sunlight. This review aims to provide insight into the relationship between ancillary ligand structure and DSSC properties, which can further guide the function-oriented design and synthesis of different sensitizers for DSSCs. This review outlines how the new and rapidly expanding class of chelating ancillary ligands bearing 2,2'-bipyridyl, 1,10-phenanthroline, carbene, dipyridylamine, pyridyl-benzimidazole, pyridyl-azolate, and other aromatic ligands provides a conduit for potentially enhancing the performance and stability of DSSCs. Finally, these classes of Ru polypyridyl complexes have gained increasing interest for feasible large-scale commercialization of DSSCs due to their more favorable light-harvesting abilities and long-term thermal and chemical stabilities compared with other conventional sensitizers. Therefore, the main idea is to inspire readers to explore new avenues in the design of new sensitizers for DSSCs based on different ancillary ligands. PMID:27479482

  2. Market and policy barriers for demand response providing ancillary services in U.S. markets

    SciTech Connect

    Cappers, Peter; MacDonald, Jason; Goldman, Charles

    2013-03-01

    This study provides an examination of various market and policy barriers to demand response providing ancillary services in both ISO/RTO and non-ISO/RTO regions, especially at the program provider level. It is useful to classify barriers in order to create a holistic understanding and identify parties that could be responsible for their removal. This study develops a typology of barriers focusing on smaller customers that must rely on a program provider (i.e., electric investor owned utility or IOU, ARC) to create an aggregated DR resource in order to bring ancillary services to the balancing authority. The barriers were identified through examinations of regulatory structures, market environments, and product offerings; and discussions with industry stakeholders and regulators. In order to help illustrate the differences in barriers among various wholesale market designs and their constituent retail environments, four regions were chosen to use as case studies: Colorado, Texas, Wisconsin, and New Jersey.

  3. Commercial Building Loads Providing Ancillary Services in PJM

    SciTech Connect

    MacDonald, Jason; Kiliccote, Sila; Boch, Jim; Chen, Jonathan; Nawy, Robert

    2014-06-27

    The adoption of low carbon energy technologies such as variable renewable energy and electric vehicles, coupled with the efficacy of energy efficiency to reduce traditional base load has increased the uncertainty inherent in the net load shape. Handling this variability with slower, traditional resources leads to inefficient system dispatch, and in some cases may compromise reliability. Grid operators are looking to future energy technologies, such as automated demand response (DR), to provide capacity-based reliability services as the need for these services increase. While DR resources are expected to have the flexibility characteristics operators are looking for, demonstrations are necessary to build confidence in their capabilities. Additionally, building owners are uncertain of the monetary value and operational burden of providing these services. To address this, the present study demonstrates the ability of demand response resources providing two ancillary services in the PJM territory, synchronous reserve and regulation, using an OpenADR 2.0b signaling architecture. The loads under control include HVAC and lighting at a big box retail store and variable frequency fan loads. The study examines performance characteristics of the resource: the speed of response, communications latencies in the architecture, and accuracy of response. It also examines the frequency and duration of events and the value in the marketplace which can be used to examine if the opportunity is sufficient to entice building owners to participate.

  4. Cohort Profile: Longitudinal Investigations into Supportive and Ancillary health services.

    PubMed

    Duncan, Katrina C; Salters, Kate; Forrest, Jamie I; Palmer, Alexis K; Wang, Hong; O'Brien, Nadia; Parashar, Surita; Cescon, Angela M; Samji, Hasina; Montaner, Julio Sg; Hogg, Robert S

    2013-08-01

    The Longitudinal Investigations into Supportive and Ancillary health services (LISA) study is a cohort of people living with HIV/AIDS who have ever accessed anti-retroviral therapy (ART) in British Columbia, Canada. The LISA study was developed to better understand the outcomes of people living with HIV with respect to supportive services use, socio-demographic factors and quality of life. Between July 2007 and January 2010, 1000 participants completed an interviewer-administered questionnaire that included questions concerning medical history, substance use, social and medical support services, food and housing security and other social determinants of health characteristics. Of the 1000 participants, 917 were successfully linked to longitudinal clinical data through the provincial Drug Treatment Program. Within the LISA cohort, 27% of the participants are female, the median age is 39 years and 32% identify as Aboriginal. Knowledge translation activities for LISA include the creation of plain language summaries, internet resources and arts-based engagement activities such as Photovoice. PMID:22461127

  5. Diagnostic Implication and Clinical Relevance of Ancillary Techniques in Clinical Pathology Practice

    PubMed Central

    Makki, Jaafar S.

    2016-01-01

    Hematoxylin–eosin-stained slide preparation is one of the most durable techniques in medicine history, which has remained unchanged since implemented. It allows an accurate microscopic diagnosis of the vast majority of tissue samples. In many circumstances, this technique cannot answer all the questions posed at the initial diagnostic level. The pathologist has always been looking for additional ancillary techniques to answer pending questions. In our daily histopathology practice, we referred to those techniques as special stains, but nowadays, they are more than stains and are collectively called ancillary tests. They include a wide range of techniques starting from histochemical stains and ending in one or more advanced techniques, such as immunohistochemistry, immunofluorescence, molecular studies, cytogenetic studies, electron microscopy, flow cytometry, and polymerase chain reaction. PMID:27042154

  6. Ascent/descent ancillary data production user's guide

    NASA Technical Reports Server (NTRS)

    Brans, H. R.; Seacord, A. W., II; Ulmer, J. W.

    1986-01-01

    The Ascent/Descent Ancillary Data Product, also called the A/D BET because it contains a Best Estimate of the Trajectory (BET), is a collection of trajectory, attitude, and atmospheric related parameters computed for the ascent and descent phases of each Shuttle Mission. These computations are executed shortly after the event in a post-flight environment. A collection of several routines including some stand-alone routines constitute what is called the Ascent/Descent Ancillary Data Production Program. A User's Guide for that program is given. It is intended to provide the reader with all the information necessary to generate an Ascent or a Descent Ancillary Data Product. It includes descriptions of the input data and output data for each routine, and contains explicit instructions on how to run each routine. A description of the final output product is given.

  7. OFT ascent/descent ancillary data requirements document

    NASA Technical Reports Server (NTRS)

    Bond, A. C., Jr.; Abramson, B.

    1978-01-01

    Requirements are presented for the ascent/descent (A/D) navigation and attitude-dependent ancillary data products to be generated for the space shuttle orbiter in support of orbital flight test requirements, MPAD guidance and navigation performance assessment, and the mission evaluation team. It was intended that this document serve as the sole requirements control instrument between MPB/MPAD and the A/D ancillary data users. The requirements are primarily functional in nature, but some detail level requirements are also included.

  8. Shuttle program: OFT ascent/descent ancillary data requirements document

    NASA Technical Reports Server (NTRS)

    Bond, A. C., Jr.; Knoedler, J.

    1980-01-01

    Requirements are presented for the ascent/descent (A/D) navigation and attitude-dependent ancillary data products to be generated for the space shuttle orbiter in support of the orbital flight test (OFT) flight test requirements, MPAD guidance and navigation performance assessment, and the mission evaluation team. The A/D ancillary data support for OFT mission evaluation activities is confined to providing postflight position, velocity, attitude, and associated navigation and attitude derived parameters for the Orbiter over particular flight phases and time intervals.

  9. Weak Ligand-Field Effect from Ancillary Ligands on Enhancing Single-Ion Magnet Performance.

    PubMed

    Meng, Yin-Shan; Zhang, Yi-Quan; Wang, Zhe-Ming; Wang, Bing-Wu; Gao, Song

    2016-08-26

    A series of bis-pentamethylcyclopentadienyl-supported Dy complexes containing different ancillary ligands were synthesized and characterized. Magnetic studies showed that 1 Dy [Cp*2 DyCl(THF)], 1 Dy' [Cp*2 DyCl2 K(THF)]n , 2 Dy [Cp*2 DyBr(THF)], 3 Dy [Cp*2 DyI(THF)] and 4 Dy [Cp*2 DyTp] (Tp=hydrotris(1-pyrazolyl)borate) were single-ion magnets (SIMs). The 1D dysprosium chain 1 Dy' exhibited a hysteresis at up to 5 K. Furthermore, 3 Dy featured the highest energy barrier (419 cm(-1) ) among the complexes. The effects of ancillary ligands on single-ion magnetic properties were studied by experimental, ab initio calculations and electrostatic analysis methods in detail. These results demonstrated that the QTM rate was strongly dependent on the ancillary ligands and that a weak equatorial ligand field could be beneficial for constructing Dy-SIMs. PMID:27417884

  10. Staff working in ancillary departments at a tertiary care hospital in Bengaluru, Karnataka, India: How healthy are they?

    PubMed Central

    Balasubramanya, Bhavya; Nisha, Catherin; Ramesh, Naveen; Joseph, Bobby

    2016-01-01

    Background: Ancillary health services are those supplemental services other than room, board, and medical/nursing services provided to hospital patients in the course of care. Ancillary department staff forms an integral part in the smooth functioning of a hospital. There is a need to focus on the health of these individuals to ensure their well-being and in turn, productivity at the workplace. Objective: To study the morbidity profile of the staff working at ancillary departments of a tertiary care hospital in Bengaluru, Karnataka, India. Materials and Methods: We conducted our study in a 1,200-bedded tertiary care hospital in Bengaluru, Karnataka, India. Annual medical checkup (AMC) for all the staff working at the ancillary departments has been started in recent years and is provided free of cost and during working hours. A total of 150 employees from ancillary departments underwent AMC in the year 2013. Data were analyzed using Statistical Package for the Social Sciences (SPSS) version 20.0. Spearman's correlation and Chi-square test were used. Results: Of the 150 employees, the majority was male (72%); the mean age was 38 ± 11 years. The most common morbidities were diabetes mellitus (11%), hypertension (10.6%), musculoskeletal disorders (9.3%), surgical problems (8.6%, hemorrhoids, varicose veins), and dental caries (6.6%). On stool microscopy, 12% of the dietary workers showed ova/cyst. There was a significant positive correlation between age and the number of chronic morbidities (P < 0.01). Conclusion: Lifestyle disorders such as diabetes mellitus and hypertension were the major morbidities among the staff in the ancillary departments of the hospital. We ensured regular follow-up, adherence to medication, and lifestyle modifications in terms of diet and exercise. PMID:27390479

  11. VITAL-Bone Health: rationale and design of two ancillary studies evaluating the effects of vitamin D and/or omega-3 fatty acid supplements on incident fractures and bone health outcomes in the VITamin D and OmegA-3 TriaL (VITAL)

    PubMed Central

    LeBoff, Meryl S.; Yue, Amy Y.; Copeland, Trisha; Cook, Nancy R.; Buring, Julie E.; Manson, JoAnn E.

    2015-01-01

    Rationale Although vitamin D is widely used to promote skeletal health, definitive data on benefits and risks of supplemental vitamin D alone on bone are lacking. Results from large, randomized controlled trials in the general population are sparse. Data on the effects of supplemental omega-3 fatty acids (FAs) on bone are also limited. Design The VITamin D and OmegA-3 TriaL (VITAL) is a double-blind, placebo-controlled trial assessing the role of vitamin D3 (2000 IU/d) and omega-3 FA (1 g/d) supplements in reducing risks of cancer and cardiovascular disease among U.S. men aged ≥50 and women aged ≥55. To comprehensively test effects of supplemental vitamin D and/or omega-3 FAs on skeletal health, the VITAL: Effects on Fractures ancillary study is determining the effects of these supplements on incident fractures among 25,875 participants enrolled in the parent trial. Study investigators adjudicate fractures through detailed review of medical records and radiological images (hip and femur). In a complementary ancillary, VITAL: Effects on Structure and Architecture is determining the effects of supplemental vitamin D and/or omega-3 FAs on bone with detailed phenotyping during in-person visits. Comprehensive assessments of bone density, turnover, structure/architecture, body composition, and physical performance are being performed at baseline and 2 years post-randomization. Conclusion Results from these studies will clarify the relationship between supplemental vitamin D and/or omega-3 FAs on bone health outcomes, and inform clinical care and public health guidelines on the use of supplemental vitamin D for the primary prevention of fractures in women and men. PMID:25623291

  12. Financial Report of Ontario Universities 1995-96. Ancillary Enterprises.

    ERIC Educational Resources Information Center

    Council of Ontario Universities, Toronto.

    This supplementary volume has been compiled from submissions prepared by each of the provincially assisted universities and federated and affiliated colleges of Ontario (Canada). The information in this volume provides further details concerning sources of revenue and types of expenses as reported for various ancillary operations. These include…

  13. 76 FR 41726 - Reporting Ancillary Airline Passenger Revenues

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... reservations, transportation of unaccompanied minors, pet transportation, third-party services such as hotel..., delay or loss of wheelchairs or scooters transported in the aircraft cargo would be minimal for carriers... and Loss Elements * * * * * Schedule P-9 Statement of Ancillary Revenues (a) Section 24 Profit...

  14. Fundamental design issues in markets for ancillary services

    SciTech Connect

    Rebours, Yann; Kirschen, Daniel; Trotignon, Marc

    2007-07-15

    While ancillary services are an essential feature of electricity markets, the designs of markets for these services have known ad hoc evolutions. A comprehensive approach is needed, requiring the solving of nine fundamental issues to create the most efficient markets. (author)

  15. The Production and Archiving of Navigation and Ancillary Data for the Galileo Mission

    NASA Technical Reports Server (NTRS)

    Miller, J.; Clarke, T.

    1994-01-01

    The Galileo Mission to Jupiter is using the SPICE formats developed by the Navigation and Ancillary Information Facility, a node of the Planetary Data System, to archive its navigation and ancillary data.

  16. Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the Carotenoids in Age-Related Eye Disease Study (CAREDS), an ancillary study of the Women’s Health Initiative

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The purpose of this study was to examine the relationship between lutein and zeaxanthin in the diet and serum and prevalence of age-related nuclear cataract in older women. Women’s Health Initiative Observational Study participants aged 50 y+, at 3 sites, who reported high (above the 78th percentile...

  17. 47 CFR 25.255 - Procedures for resolving harmful interference related to operation of ancillary terrestrial...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... related to operation of ancillary terrestrial components operating in the 1.5/1.6 GHz and 1.6/2.4 GHz... interference related to operation of ancillary terrestrial components operating in the 1.5/1.6 GHz and 1.6/2.4 GHz bands. If harmful interference is caused to other services by ancillary MSS ATC operations,...

  18. 47 CFR 25.255 - Procedures for resolving harmful interference related to operation of ancillary terrestrial...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... harmful interference related to operation of ancillary terrestrial components operating in the 1.5./1.6 GHz, 1.6/2.4 GHz and 2 GHz bands. If harmful interference is caused to other services by ancillary MSS... related to operation of ancillary terrestrial components operating in the 1.5./1.6 GHz, 1.6/2.4 GHz and...

  19. 47 CFR 25.255 - Procedures for resolving harmful interference related to operation of ancillary terrestrial...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... related to operation of ancillary terrestrial components operating in the 1.5/1.6 GHz and 1.6/2.4 GHz... interference related to operation of ancillary terrestrial components operating in the 1.5/1.6 GHz and 1.6/2.4 GHz bands. If harmful interference is caused to other services by ancillary MSS ATC operations,...

  20. Association between dietary fats and age-related macular degeneration (AMD) in the Carotenoids in Age-Related Eye Disease Study (CAREDS), an ancillary study of the Women’s Health Initiative123

    PubMed Central

    Parekh, Niyati; Voland, Rickie P.; Moeller, Suzen M.; Blodi, Barbara A.; Ritenbaugh, Cheryl; Chappell, Richard J.; Wallace, Robert B.; Mares, Julie A.

    2011-01-01

    Objective Evaluating relationships of amount and type of dietary fat to intermediate AMD. Design Women, ages 50–79, from the Women’s Health Initiative-Observational Study, with high and low lutein intakes, were recruited into the Carotenoids in Age-Related Eye Disease Study (CAREDS). Fat intake in 1994–1998 was estimated using food frequency questionnaires. AMD was assessed in 2001–2004 from stereoscopic fundus photographs. Results Intakes of omega-6 and omega-3 polyunsaturated fats (ω-6 and ω-3 PUFA), which were highly correlated (r=0.8), were associated with higher prevalence of intermediate AMD. Significant age-interactions were noted for associations with total fat, monounsaturated and saturated fat (p= 0.01–0.02). In women <75 years (n=1,325), diets high in total fat (% energy) were associated with increased prevalence of AMD (OR (95% CI) for quintile five vs. one = 1.73 (1.02–2.7; p-trend=0.10); the association was reversed in older women. Monounsaturated fat (MUFA) intakes in quintiles three through five vs. one were associated with lower prevalence of AMD in the whole population. Conclusions Overall associations of dietary fat to AMD differed by type of fat and, often, by age in this cohort. These findings contribute insights about sources of inconsistencies of fat to AMD in epidemiological studies. PMID:19901214

  1. Unanticipated Consequences: Thinking About Ancillary Benefits and Costs of Greenhouse Gas Emissions Mitigation

    SciTech Connect

    Edmonds, James A.

    2005-03-31

    Recently there has been interest in the “ancillary benefits” of potential policies to address climate change. Ancillary benefits occur whenever a policy to address climate change also results in a reduction in some conventional pollutant. Framing the problem in terms of ancillary benefits is too narrow. In general implementation of any policy can have consequences for unpriced environmental externalities that extend beyond the original target of the policy. These ancillary consequences can be either positive, negative, or mixed. This is the inevitable implication of undertaking policy in a non-linear world. In this essay we explore some of the ancillary benefits and costs of addressing climate change.

  2. Quantum computation mediated by ancillary qudits and spin coherent states

    NASA Astrophysics Data System (ADS)

    Proctor, Timothy J.; Dooley, Shane; Kendon, Viv

    2015-01-01

    Models of universal quantum computation in which the required interactions between register (computational) qubits are mediated by some ancillary system are highly relevant to experimental realizations of a quantum computer. We introduce such a universal model that employs a d -dimensional ancillary qudit. The ancilla-register interactions take the form of controlled displacements operators, with a displacement operator defined on the periodic and discrete lattice phase space of a qudit. We show that these interactions can implement controlled phase gates on the register by utilizing geometric phases that are created when closed loops are traversed in this phase space. The extra degrees of freedom of the ancilla can be harnessed to reduce the number of operations required for certain gate sequences. In particular, we see that the computational advantages of the quantum bus (qubus) architecture, which employs a field-mode ancilla, are also applicable to this model. We then explore an alternative ancilla-mediated model which employs a spin ensemble as the ancillary system and again the interactions with the register qubits are via controlled displacement operators, with a displacement operator defined on the Bloch sphere phase space of the spin coherent states of the ensemble. We discuss the computational advantages of this model and its relationship with the qubus architecture.

  3. Multi-Ethnic Study of Atherosclerosis (MESA) - Ancillary Eye Study

    ClinicalTrials.gov

    2016-02-05

    Atherosclerosis; Cardiovascular Diseases; Coronary Arteriosclerosis; Coronary Disease; Cerebrovascular Disorders; Heart Failure, Congestive; Myocardial Infarction; Heart Diseases; Diabetes Mellitus, Non-insulin Dependent; Hypertension; Diabetic Retinopathy; Macular Degeneration; Diabetes Mellitus

  4. Inhaled hyaluronic acid as ancillary treatment in children with bacterial acute rhinopharyngitis.

    PubMed

    Varricchio, A; Capasso, M; Avvisati, F; Varricchio, A M; De Lucia, A; Brunese, F P; Ciprandi, G

    2014-01-01

    Acute rhinopharyngitis (ARP) is the most common upper respiratory infection in children and represents a social problem for both the pharmaco-economic impact and a burden for the family. Topical antibiotic therapy is usually effective in bacterial ARP, but ancillary treatment might improve its efficacy. Hyaluronic acid (HA) is a promising molecule that has been recently proposed in upper respiratory disorders. Therefore, the purpose of this study was to evaluate the effects of ancillary HA treatment in children with bacterial ARP. Globally, 51 children (27 males, mean age 5.9 ± 2.1 years) with bacterial ARP were enrolled in the study. At baseline, children were randomly assigned to the treatment with: 125 mg of thiamphenicol diluted in 4 mL of saline isotonic solution twice daily (group A) or with 125 mg of thiamphenicol plus 4 ml of sodium hyaluronate 0.2% plus xylitol 5% (Aluneb, Sakura Italia) twice daily (group B) administered by the nasal device Rinowash (Airliquide Medical System, Italy) and connected to an aerosol nebulizer with pneumatic compressor (1.5 bar per 5 L/min) Nebula (Airliquide Medical System, Italy), for 10 days. sVAS, nasopharyngeal spotting, neutrophils and bacteria were assessed at baseline and after the treatment. Both treatments induced significant reduction of symptom perception, spotting, neutrophil and bacteria count. However, thiamphenicol plus HA was able to significantly induce a greater effect on sVAS (p=0.006), neutrophil count (p=0.01), and bacteria count (p=0.0003) than thiamphenicol alone. In conclusion, this study provides the first evidence that intranasal HA, as ancillary treatment, may be able to improve topical antibiotic efficacy in children with bacterial ARP. PMID:25316142

  5. Identifying children in need of ancillary and enabling services: a population approach.

    PubMed

    Benedict, Ruth E; Farel, Anita M

    2003-12-01

    Children with chronic or disabling conditions use health, education and social services at a higher rate than their healthy peers. Estimates of the number of children in need of these specialized services are widely varied and often depend on categorical definitions that do not account for either the diversity or commonality of their experiences. Developing methods for identifying the population in need of services, particularly children likely to use long-term ancillary (audiology, occupational, physical or speech therapy, or social work) and/or enabling services (special equipment, personal care assistance, respite care, transportation, or environmental modifications), is essential for effective policy and program implementation. This study examines several recent attempts to operationalize definitions of children with chronic conditions using a noncategorical classification approach. Particular emphasis is placed on the subgroup of children identified as having functional limitations. Proposed operational definitions of children with functional limitations are compared using data from the 1994-1995 Disability Supplement to the US National Health Interview Survey. Estimates of the number of children reported to be using ancillary and enabling services are generated and compared across operational definitions of functional limitation as well as by the number, severity, and type (i.e. mobility, self-care, communication/sensory, social cognition/learning ability) of limitation. Depending on the operational definition selected, 9-14% of US community-dwelling children are estimated to have functional limitations. Among children with limitations, 26-30% regularly use ancillary services and 11-14% use enabling services. The strengths, limitations, and potential applications for each operational definition are discussed. PMID:14512235

  6. Ancillary procedures necessary for translational research in experimental craniomaxillofacial surgery

    PubMed Central

    Al Rakan, Mohammed; Shores, Jaimie T.; Bonawitz, Steve; Santiago, Gabriel; Christensen, Joani M.; Grant, Gerald; Murphy, Ryan J.; Basafa, Ehsan; Armand, Mehran; Otovic, Pete; Eller, Sue; Brandacher, Gerald; Gordon, Chad R.

    2014-01-01

    Introduction Swine are often regarded as having analogous facial skeletons to humans and therefore serve as an ideal animal model for translational investigation. However, there's a dearth of literature describing the pertinent ancillary procedures required for craniomaxillofacial research. With this in mind, our objective was to evaluate all necessary procedures required for peri-operative management and animal safety related to experimental craniomaxillofacial surgical procedures such as orthotopic, maxillofacial transplantation. Methods Miniature swine (n=9) were used to investigate peri-operative airway management, methods for providing nutrition, and long-dwelling intravenous access. Flap perfusion using near-infrared laser angiography and facial nerve assessment with EMG were explored. Results Bivona(R) tracheostomy was deemed appropriate versus Shiley since soft, wire-reinforced tubing reduced the incidence of tracheal necrosis. PEG tube, as opposed to esophagostomy, provided a reliable route for post-operative feeding. Femoral venous access with dorsal tunneling proved to be an ideal option being far from pertinent neck vessels. Laser angiography was beneficial for real-time evaluation of graft perfusion. Facial EMG techniques for tracing capture were found most optimal using percutaneous leads near the oral commissure. Experience shows that ancillary procedures are critical and malpositioning of devices may lead to irreversible sequelae with premature animal death. Conclusion Face-jaw-teeth transplantation in swine is a complicated procedure which demands special attention to airway, feeding, and intravascular access. It is critical that each ancillary procedure be performed by a dedicated team familiar with relevant anatomy and protocol. Emphasis should be placed on secure skin-level fixation for all tube/lines to minimize risk of dislodgement. A reliable veterinarian team is invaluable and critical for long-term success. PMID:25377964

  7. Demand Response Resources for Energy and Ancillary Services (Presentation)

    SciTech Connect

    Hummon, M.

    2014-04-01

    Demand response (DR) resources present a potentially important source of grid flexibility particularly on future systems with high penetrations of variable wind an solar power generation. However, DR in grid models is limited by data availability and modeling complexity. This presentation focuses on the co-optimization of DR resources to provide energy and ancillary services in a production cost model of the Colorado test system. We assume each DR resource can provide energy services by either shedding load or shifting its use between different times, as well as operating

  8. 19. VIEW LOOKING SOUTHWEST TOWARDS THE ANCILLARY BUILDINGS. FROM LEFT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. VIEW LOOKING SOUTHWEST TOWARDS THE ANCILLARY BUILDINGS. FROM LEFT TO RIGHT BACKGROUND, RETORT BUILDING, STORAGE, SMELTER BUILDING, GARAGE. THE NORTHWEST CORNER OF THE VANNER ROOM IS IN THE FOREGROUND AND LEFT. A 2000 DODGE GRAND CARAVAN IS IN THE FOREGROUND CENTER. THEIR USE OF THE SHED TO THE REAR OF THE AUTOMOBILE IS UNCERTAIN, ALTHOUGH IT IS CONNECTED TO THE MILL AT THE BASE OF THE WEST SIDE OF THE AMALGAMATING PANS ROOM. - Standard Gold Mill, East of Bodie Creek, Northeast of Bodie, Bodie, Mono County, CA

  9. The APOGEE Low-Mass Star Ancillary Project

    NASA Astrophysics Data System (ADS)

    Blake, Cullen; Mahadevan, Suvrath; Deshpande, Rohit; Bender, Chad F.; Terrien, Ryan; Crepp, Justin R.; Carlberg, Joleen K.; Nidever, David L.; Stassun, Keivan; Hawley, Suzanne L.; Hearty, Fred; Allende-Prieto, Carlos

    2015-01-01

    As a high-resolution, near-infrared, fiber-fed instrument, APOGEE presents a unique opportunity to obtain multi-epoch radial velocity measurements of a large number of low-mass stars. These observations will reveal unseen companions, improving our understanding of stellar multiplicity at the bottom of the Main Sequence, and may even identify candidate sub-stellar companions. These same data contains an unprecedented wealth of information about the kinematics, rotation, and metallicities of these stars. I will describe the status of our Ancillary Science program, and ongoing efforts to get the best possible radial velocity precision from the APOGEE data.

  10. National Ignition Facility sub-system design requirements ancillary systems SSDR 1.5.6

    SciTech Connect

    Spann, J.; Reed, R.; VanArsdall, P.; Bliss, E.

    1996-09-01

    This System Design Requirement document establishes the performance, design, development, and test requirements for the Ancillary Systems, which is part of the NIF Integrated Computer Control System (ICCS).

  11. Immunohistochemistry and other ancillary techniques in the diagnosis of gestational trophoblastic diseases.

    PubMed

    Buza, Natalia; Hui, Pei

    2014-05-01

    Gestational trophoblastic disease (GTD) encompasses entities ranging from ubiquitous hydatidiform moles to rare neoplastic gestational trophoblastic tumors. In practice, the histological diagnosis of GTD continues to have significant diagnostic inaccuracy with marked inter- and intra-observer variability, even among expert pathologists. Studies in correlation with genotypic evidence have confirmed a lack of accuracy in diagnosis of hydatidiform moles using histology alone. Applications of new immunohistochemical markers and molecular techniques have significantly enhanced the diagnostic precision of various GTDs in recent years. p57 Immunohistochemistry is a highly useful marker in confirming complete hydatidiform mole. PCR-based DNA genotyping has emerged as a powerful diagnostic measure to precisely classify both complete and partial hydatidiform moles. With acquisition of molecular diagnostic capabilities at most medical centers, these ancillary techniques have been increasingly integrated into the routine diagnostic workup of GTD. We propose an algorithmic approach combining histology and these ancillary tests to provide the best diagnostic practice possible. Under this algorithm, all cases with histological suspicion for complete mole are subject to p57 immunohistochemical confirmation, and all cases with histological suspicion for partial mole undergo DNA genotyping workup. Beyond hydatidiform mole, recognition of gestational trophoblastic tumors requires a high index of suspicion and application of immunohistochemical markers of trophoblast is helpful to accurately diagnose these rare tumors. PMID:24907943

  12. Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study

    PubMed Central

    Del Brutto, Oscar H.; Sedler, Mark J.; Mera, Robertino M.; Castillo, Pablo R.; Cusick, Elizabeth H.; Gruen, Jadry A.; Phelan, Kelsie J.; Del Brutto, Victor J.; Zambrano, Mauricio; Brown, David L.

    2014-01-01

    Background. Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. Study design. Population-based study in Atahualpa. In Phase I, the Edinburgh claudication questionnaire (ECQ) was used for detection of suspected symptomatic PAD; persons with a negative ECQ but a pulse pressure ≥65 mmHg were suspected of asymptomatic PAD. In Phase II, the ankle-brachial index will be used to test reliability of screening instruments and to determine PAD prevalence. In Phase III, participants will be followed up to estimate the relevance of PAD as a predictor of vascular outcomes. Results. During Phase I, 665 Atahualpa residents aged ≥40 years were enrolled (mean age: 59.5 ± 12.6 years, 58% women). A poor cardiovascular health status was noticed in 464 (70%) persons of which 27 (4%) had a stroke and 14 (2%) had ischemic heart disease. Forty-four subjects (7%) had suspected symptomatic PAD and 170 (26%) had suspected asymptomatic PAD. Individuals with suspected PAD were older, more often women, and had a worse cardiovascular profile than those with nonsuspected PAD. Conclusions. Prevalence of suspected PAD in this underserved population is high. Subsequent phases of this study will determine whether prompt detection of PAD is useful to reduce the incidence of catastrophic vascular diseases in the region. PMID:25389500

  13. 47 CFR 25.255 - Procedures for resolving harmful interference related to operation of ancillary terrestrial...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Procedures for resolving harmful interference related to operation of ancillary terrestrial components operating in the 1.5./1.6 GHz, 1.6/2.4 GHz and 2... harmful interference related to operation of ancillary terrestrial components operating in the...

  14. 47 CFR 25.255 - Procedures for resolving harmful interference related to operation of ancillary terrestrial...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Procedures for resolving harmful interference related to operation of ancillary terrestrial components operating in the 1.5./1.6 GHz, 1.6/2.4 GHz and 2... harmful interference related to operation of ancillary terrestrial components operating in the...

  15. 10 CFR 205.199G - Extension of time; Interim and Ancillary Orders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Extension of time; Interim and Ancillary Orders. 205.199G... Extension of time; Interim and Ancillary Orders. The Director of the Office of Hearings and Appeals or his... to FERC to be amended or withdrawn after it has been filed or to be filed within a time...

  16. 10 CFR 205.199G - Extension of time; Interim and Ancillary Orders.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Extension of time; Interim and Ancillary Orders. 205.199G... Extension of time; Interim and Ancillary Orders. The Director of the Office of Hearings and Appeals or his... to FERC to be amended or withdrawn after it has been filed or to be filed within a time...

  17. 48 CFR 801.670-3 - Medical, dental, and ancillary service.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Medical, dental, and..., Contracting Authority, and Responsibilities 801.670-3 Medical, dental, and ancillary service. (a) When medical, dental, and ancillary services under $10,000 per authorization are not available from an...

  18. 48 CFR 801.670-3 - Medical, dental, and ancillary service.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Medical, dental, and..., Contracting Authority, and Responsibilities 801.670-3 Medical, dental, and ancillary service. (a) When medical, dental, and ancillary services under $10,000 per authorization are not available from an...

  19. 48 CFR 801.670-3 - Medical, dental, and ancillary service.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Medical, dental, and..., Contracting Authority, and Responsibilities 801.670-3 Medical, dental, and ancillary service. (a) When medical, dental, and ancillary services under $10,000 per authorization are not available from an...

  20. 48 CFR 801.670-3 - Medical, dental, and ancillary service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Medical, dental, and..., Contracting Authority, and Responsibilities 801.670-3 Medical, dental, and ancillary service. (a) When medical, dental, and ancillary services under $10,000 per authorization are not available from an...

  1. 48 CFR 801.670-3 - Medical, dental, and ancillary service.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Medical, dental, and..., Contracting Authority, and Responsibilities 801.670-3 Medical, dental, and ancillary service. (a) When medical, dental, and ancillary services under $10,000 per authorization are not available from an...

  2. 47 CFR 1.9049 - Special provisions relating to spectrum leasing arrangements involving the ancillary terrestrial...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... arrangements involving the ancillary terrestrial component of Mobile Satellite Services. 1.9049 Section 1.9049... arrangements involving the ancillary terrestrial component of Mobile Satellite Services. (a) A license issued... Mobile Satellite Service licensee with an ATC authorization may enter into a spectrum manager...

  3. 47 CFR 1.9049 - Special provisions relating to spectrum leasing arrangements involving the ancillary terrestrial...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... arrangements involving the ancillary terrestrial component of Mobile Satellite Services. 1.9049 Section 1.9049... arrangements involving the ancillary terrestrial component of Mobile Satellite Services. (a) A license issued... Mobile Satellite Service licensee with an ATC authorization may enter into a spectrum manager...

  4. 47 CFR 1.9049 - Special provisions relating to spectrum leasing arrangements involving the ancillary terrestrial...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... arrangements involving the ancillary terrestrial component of Mobile Satellite Services. 1.9049 Section 1.9049... arrangements involving the ancillary terrestrial component of Mobile Satellite Services. (a) A license issued... Mobile Satellite Service licensee with an ATC authorization may enter into a spectrum manager...

  5. 47 CFR 1.9049 - Special provisions relating to spectrum leasing arrangements involving the ancillary terrestrial...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... arrangements involving the ancillary terrestrial component of Mobile Satellite Services. 1.9049 Section 1.9049... ancillary terrestrial component of Mobile Satellite Services. (a) A license issued under part 25 of the...” for purpose of this subpart of the rules. (b) For the purpose of this subpart, a Mobile...

  6. 76 FR 55890 - Cancellation of Supplemental Environmental Impact Statement for Ancillary Facilities for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... Record of Decision (ROD) (72 FR 7964; February 22, 2007), DOE announced its selection of Richton... some of the ancillary facilities associated with the Richton site: the raw water intake structure, oil... new locations for the ancillary facilities associated with the Richton site (73 FR 11895; March...

  7. 30 CFR 550.207 - What ancillary activities may I conduct?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What ancillary activities may I conduct? 550.207 Section 550.207 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Ancillary Activities § 550.207 What...

  8. Analysis of wind power ancillary services characteristics with German 250-MW wind data

    SciTech Connect

    Ernst, B.

    1999-12-09

    With the increasing availability of wind power worldwide, power fluctuations have become a concern for some utilities. Under electric industry restructuring in the US, the impact of these fluctuations will be evaluated by examining provisions and costs of ancillary services for wind power. This paper analyzes wind power in the context of ancillary services, using data from a German 250 Megawatt Wind project.

  9. Map of risks for the implementation of radio-frequency identification: application of ancillaries in the University Hospital Jean Verdier.

    PubMed

    Bertrand, E; Schlatter, J

    2010-01-01

    Ancillaries are surgical instruments, such as orthopedical instruments set for reconstruction of knee (a mounting arm...) used to implant or extract prosthesis. Their management involves the departments of sterilization and surgery as well as the suppliers. Such a long circuit exposes the instruments to potential risk hazards like a lack of traceability as the suspicion of Creutzfeldt-Jakob. In order to reduce the risk of errors we will propose the implementation of radio-frequency identification (RFID) to trace the ancillaries during each step of the supply chain. The objective of our study is to analyze and to map the risks associated with RFID implementation. A preliminary analysis of risks (APR) is conducted to map out the hazards for the implementation of RFID. The APR identifies 162 scenarios with a maximum risk connected to environment and technology. To reduce the risks identified, 22 courses of action are proposed, such as audits, training, and internal controls. For each action, a procedure has been designed and evaluated. This preliminary analysis of risks allows targeting the potential dangers for the RFID implementation applied to ancillaries and reduces them significantly. PMID:20187581

  10. Attitude of ancillary personnel faced with living kidney donation in a hospital with a living donor kidney transplant program.

    PubMed

    Ríos, Antonio; Ramírez, Pablo; del Mar Rodríguez, María; Martínez, Lewa; Montoya, Mariano Jeime; Lucas, Dolores; Alcaraz, Jesús; Parrilla, Pascual

    2007-02-15

    Hospital ancillary workers' opinion has credibility among the general public because they work on behalf of a hospital. The objective of this study is to analyze the attitude of ancillary employees toward living kidney donation and the variables that influence such attitude. A random sample of ancillary personnel (n=401) was taken and stratified according to type of service in a transplant hospital. Attitude was evaluated using a survey, which was completed anonymously and self-administered. The completion rate was 94% (n=377). Most (85%) are in favor of related living kidney donation, 7% against, and the 8% undecided. The multivariate analysis found that the variables with more weight affecting attitude are: 1) female sex (odds ratio [OR]=3.75); 2) a respondent's lack of concern about the possible "mutilation" of the body after donation (OR=3.65); 3) a respondent's belief in the possibility of needing a future transplant (OR=2.66); and 4) a respondent's willingness to receive a donated living kidney (OR=10.51). PMID:17297409

  11. Effective Ancillary Services Market Designs on High Wind Power Penetration Systems: Preprint

    SciTech Connect

    Ela, E.; Kirby, B.; Navid, N.; Smith, J. C.

    2011-12-01

    This paper focuses on how the ancillary service market designs are implemented and how they may require changes on systems with greater penetrations of variable renewable energy suppliers, in particular wind power. Ancillary services markets have been developed in many of the restructured power system regions throughout the world. Ancillary services include the services that support the provision of energy to support power system reliability. The ancillary services markets are tied tightly to the design of the energy market and to the physics of the system and therefore careful consideration of power system economics and engineering must be considered in their design. This paper focuses on how the ancillary service market designs are implemented and how they may require changes on systems with greater penetrations of variable renewable energy suppliers, in particular wind power.

  12. Candidate Gene Association Study of Coronary Artery Calcification in Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort Study

    PubMed Central

    Ferguson, Jane F; Matthews, Gregory J; Townsend, Raymond R; Raj, Dominic S; Kanetsky, Peter A.; Budoff, Matthew; Fischer, Michael J; Rosas, Sylvia E; Kanthety, Radhika; Rahman, Mahboob; Master, Stephen R; Qasim, Atif; Li, Mingyao; Mehta, Nehal N.; Shen, Haiqing; Mitchell, Braxton D; O’Connell, Jeffrey R; Shuldiner, Alan R; Ho, Weang Kee; Young, Robin; Rasheed, Asif; Danesh, John; He, Jiang; Kusek, John W; Ojo, Akinlolu O; Flack, John; Go, Alan S; Gadegbeku, Crystal A; Wright, Jackson T; Saleheen, Danish; Feldman, Harold I; Rader, Daniel J; Foulkes, Andrea S; Reilly, Muredach P

    2014-01-01

    Objectives To identify loci for coronary artery calcification (CAC) in patients with chronic kidney disease (CKD). Background CKD is associated with increased CAC and subsequent coronary heart disease (CHD) but the mechanisms remain poorly defined. Genetic studies of CAC in CKD may provide a useful strategy for identifying novel pathways in CHD. Methods We performed a candidate gene study (~2,100 genes; ~50,000 SNPs) of CAC within the Chronic Renal Insufficiency Cohort (CRIC) Study (n=1,509; 57% European, 43% African ancestry). SNPs with preliminary evidence of association with CAC in CRIC were examined for association with CAC in PennCAC (n=2,560) and Amish Family Calcification Study (AFCS; n=784) samples. SNPs with suggestive replication were further analyzed for association with myocardial infarction (MI) in the Pakistan Risk of Myocardial Infarction study (PROMIS) (n=14,885). Results Of 268 SNPs reaching P <5×10−4 for CAC in CRIC, 28 SNPs in 23 loci had nominal support (P <0.05 and in same direction) for CAC in PennCAC or AFCS. Besides chr9p21 and COL4A1, known loci for CHD, these included SNPs having reported GWAS association with hypertension (e.g., ATP2B1). In PROMIS, four of the 23 suggestive CAC loci (chr9p21, COL4A1, ATP2B1 and ABCA4) had significant associations with MI consistent with their direction of effect on CAC. Conclusions We identified several loci associated with CAC in CKD that also relate to MI in a general population sample. CKD imparts a high risk of CHD and may provide a useful setting for discovery of novel CHD genes and pathways. PMID:23727086

  13. Transactive Control and Coordination of Distributed Assets for Ancillary Services

    SciTech Connect

    Subbarao, Krishnappa; Fuller, Jason C.; Kalsi, Karanjit; Somani, Abhishek; Pratt, Robert G.; Widergren, Steven E.; Chassin, David P.

    2013-09-18

    The need to diversify energy supplies, the need to mitigate energy-related environmental impact, and the entry of electric vehicles in large numbers present challenges and opportunities to power system professionals. Wind and solar power provide many benefits, and to reap the benefits the resulting increased variability—forecasted as well as unforecasted—should be addressed. Demand resources are receiving increasing attention as one means of providing the grid balancing services. Control and coordination of a large number (~millions) of distributed smart grid assets requires innovative approaches. One such is transactive control and coordination (TC2)—a distributed, agent-based incentive and control system. The TC2 paradigm is to create a market system with the following characteristics: • Participation should be entirely voluntary. • The participant decides at what price s/he is willing to participate. • The bids and responses are automated. Such an approach has been developed and demonstrated by Pacific Northwest National Laboratory for energy markets. It is the purpose of this project to develop a similar approach for ancillary services. In this report, the following ancillary services are considered: • spinning reserve • ramping • regulation. These services are to be provided by the following devices: • refrigerators • water heaters • clothes dryers • variable speed drives. The important results are summarized below: The regulation signal can be divided into an energy-neutral high frequency component and a low frequency component. The high frequency component is particularly well suited for demand resources. The low frequency component, which carries energy non-neutrality, can be handled by a combination of generators and demand resources. An explicit method for such a separation is obtained from an exponentially weighted moving average filter. Causal filters (i.e., filters that process only present and past values of a signal

  14. 78 FR 46177 - Third-Party Provision of Ancillary Services; Accounting and Financial Reporting for New Electric...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... Third-Party Provision of Ancillary Services; Accounting and Financial Reporting for New Electric Storage...-Party Provision of Ancillary Services; Accounting and Financial Reporting for New Electric Storage... services. \\6\\ Third-Party Provision of Ancillary Services; Accounting and Financial Reporting for...

  15. Estimating Net Primary Productivity Using Satellite and Ancillary Data

    NASA Technical Reports Server (NTRS)

    Choudhury, Bhaskar J.

    2002-01-01

    The net primary productivity (C) or the annual rate of carbon accumulation per unit ground area by terrestrial plant communities is the difference of gross photosynthesis (A(sub g)) and respiration (R) per unit ground area. Available field observations show that R is a large and variable fraction of A(sub g), although it is generally recognized that there are considerable difficulties in determining these fluxes, and thus pose challenge in assessing the accuracy. Further uncertainties arise in extrapolating field measurements (which are acquired over a hectare or so area) to regional scale. Here, an approach is presented for determining these fluxes using satellite and ancillary data to be representative of regional scale and allow assessment of interannual variation. A, has been expressed as the product of radiation use efficiency for gross photosynthesis by an unstressed canopy and intercepted photosynthetically active radiation, which is then adjusted for stresses due to soil water shortage and temperature away from optimum. R has been calculated as the sum of growth and maintenance components (respectively, R(sub g) and R(sub m)).The R(sub m) has been determined from nitrogen content of plant tissue per unit ground area, while R(sub g) has been obtained as a fraction of the difference of A(sub g) and R(sub m). Results for five consecutive years (1986-1990) are presented for the Amazon-Tocontins, Mississippi, and Ob River basins.

  16. Stable Blue Phosphorescence Iridium(III) Cyclometalated Complexes Prompted by Intramolecular Hydrogen Bond in Ancillary Ligand.

    PubMed

    Yi, Seungjun; Kim, Jin-Hyoung; Cho, Yang-Jin; Lee, Jiwon; Choi, Tae-Sup; Cho, Dae Won; Pac, Chyongjin; Han, Won-Sik; Son, Ho-Jin; Kang, Sang Ook

    2016-04-01

    Improvement of the stability of blue phosphorescent dopant material is one of the key factors for real application of organic light-emitting diodes (OLEDs). In this study, we found that the intramolecular hydrogen bonding in an ancillary ligand from a heteroleptic Ir(III) complex can play an important role in the stability of blue phosphorescence. To rationalize the role of intramolecular hydrogen bonding, a series of Ir(III) complexes is designed and prepared: Ir(dfppy)2(pic-OH) (1a), Ir(dfppy)2(pic-OMe) (1b), Ir(ppy)2(pic-OH) (2a), and Ir(ppy)2(pic-OMe) (2b). The emission lifetime of Ir(dfppy)2(pic-OH) (1a) (τem = 3.19 μs) in dichloromethane solution was found to be significantly longer than that of Ir(dfppy)2(pic-OMe) (1b) (τem = 0.94 μs), because of a substantial difference in the nonradiative decay rate (knr = 0.28 × 10(5) s(-1) for (1a) vs 2.99 × 10(5) s(-1) for (1b)). These results were attributed to the intramolecular OH···O═C hydrogen bond of the 3-hydroxy-picolinato ligand. Finally, device lifetime was significantly improved when 1a was used as the dopant compared to FIrpic, a well-known blue dopant. Device III (1a as dopant) achieved an operational lifetime of 34.3 h for an initial luminance of 400 nits compared to that of device IV (FIrpic as dopant), a value of 20.1 h, indicating that the intramolecular hydrogen bond in ancillary ligand is playing an important role in device stability. PMID:26991672

  17. Utilization of Ancillary Data Sets for SMAP Algorithm Development and Product Generation

    NASA Technical Reports Server (NTRS)

    ONeill, P.; Podest, E.; Njoku, E.

    2011-01-01

    Algorithms being developed for the Soil Moisture Active Passive (SMAP) mission require a variety of both static and ancillary data. The selection of the most appropriate source for each ancillary data parameter is driven by a number of considerations, including accuracy, latency, availability, and consistency across all SMAP products and with SMOS (Soil Moisture Ocean Salinity). It is anticipated that initial selection of all ancillary datasets, which are needed for ongoing algorithm development activities on the SMAP algorithm testbed at JPL, will be completed within the year. These datasets will be updated as new or improved sources become available, and all selections and changes will be documented for the benefit of the user community. Wise choices in ancillary data will help to enable SMAP to provide new global measurements of soil moisture and freeze/thaw state at the targeted accuracy necessary to tackle hydrologically-relevant societal issues.

  18. 21 CFR 830.340 - Voluntary submission of ancillary device identification information.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Identification Database § 830.340 Voluntary submission of ancillary device identification information. (a) You may not submit any information to the Global Unique Device Identification Database (GUDID) other...

  19. TECHNOLOGY NEEDS AND STATUS ON CLOSURE OF DOE RADIOACTIVE WASTE TANK ANCILLARY SYSTEMS

    SciTech Connect

    Burns, H; Sharon Marra, S; Christine Langton, C

    2009-01-21

    This paper summarizes the current state of art of sampling, characterizing, retrieving, transferring and treating the incidental waste and stabilizing the void space in tank ancillary systems and the needs involved with closure of these systems. The overall effort for closing tank and ancillary systems is very large and is in the initial stages of being addressed in a systematic manner. It was recognized in doing this effort, that gaps in both technology and material application for characterization and removal of residual waste and closure of ancillary systems would be identified. Great efficiencies are to be gained by defining the technology need areas early in the closure process and providing recommendations for technical programs to improve the closure strategies. Therefore, this paper will not only summarize the state of closure of ancillary systems but also provide recommendations to address the technology gaps identified in this assessment.

  20. Extending NASA's SPICE ancillary information system to meet future mission needs

    NASA Technical Reports Server (NTRS)

    Acton, C.; Bachman, N.; Elson, L.; Semenov, B.; Turner, F.; Wright, E.

    2002-01-01

    This paper summarizes the architecture, capabilities, characteristics and uses of the current SPICE ancillary information system, and then outlines plans and ideas for how this system can be extended to meet future space mission requirements.

  1. Estimating Net Primary Productivity Using Satellite and Ancillary Data

    NASA Technical Reports Server (NTRS)

    Choudhury, B. J.; Houser, Paul (Technical Monitor)

    2001-01-01

    The net primary productivity (C) or annual rate of carbon accumulation per unit ground area by terrestrial plant communities is the difference of the rate of gross photosynthesis (A(sub g)) and autotrophic respiration (R) per unit ground area. Although available observations show that R is a large and variable fraction of A(sub g), viz., 0.3 to 0.7, it is generally recognized that much uncertainties exist in this fraction due to difficulties associated with the needed measurements. Additional uncertainties arise when these measurements are extrapolated to regional or global land surface using empirical equations, for example, using regression equations relating C to mean annual precipitation and air temperature. Here, a process-based approach has been taken to calculate A(sub g) and R using satellite and ancillary data. A(sub g) has been expressed as a product of radiation use efficiency, magnitude of intercepted photosynthetically active radiation (PAR), and normalized by stresses due to soil water shortage and air temperature away from the optimum range. A biophysical model has been used to determine the radiation use efficiency from the maximum rate of carbon assimilation by a leaf, foliage temperature, and the fraction of diffuse PAR incident on a canopy. All meteorological data (PAR, air temperature, precipitation, etc.) needed for the calculation are derived from satellite observations, while a land use, land cover data (based on satellite and ground measurements) have been used to assess the maximum rate of carbon assimilation by a leaf of varied cover type based on field measurements. R has been calculated as the sum of maintenance and growth components. The maintenance respiration of foliage and live fine roots at a standard temperature of different land cover has been determined from their nitrogen content using field and satellite measurements, while that of living fraction of woody stem (viz., sapwood) from the seasonal maximum leaf area index as

  2. Evaluation of freely available ancillary data used for detailed soil mapping in Brazil

    NASA Astrophysics Data System (ADS)

    Samuel-Rosa, Alessandro; Anjos, Lúcia; Vasques, Gustavo; Heuvelink, Gerard

    2014-05-01

    Brazil is one of the world's largest food producers, and is home of both largest rainforest and largest supply of renewable fresh water on Earth. However, it lacks detailed soil information in extensive areas of the country. The best soil map covering the entire country was published at a scale of 1:5,000,000. Termination of governmental support for systematic soil mapping in the 1980's made detailed soil mapping of the whole country a very difficult task to accomplish. Nowadays, due to new user-driven demands (e.g. precision agriculture), most detailed soil maps are produced for small size areas. Many of them rely on as is freely available ancillary data, although their accuracy is usually not reported or unknown. Results from a validation exercise that we performed using ground control points from a small hilly catchment (20 km²) in Southern Brazil (-53.7995ºE, -29.6355ºN) indicate that most freely available ancillary data needs some type of correction before use. Georeferenced and orthorectified RapidEye imagery (recently acquired by the Brazilian government) has a horizontal accuracy (root-mean-square error, RMSE) of 37 m, which is worse than the value published in the metadata (32 m). Like any remote sensing imagery, RapidEye imagery needs to be correctly registered before its use for soil mapping. Topographic maps produced by the Brazilian Army and derived geological maps (scale of 1:25,000) have a horizontal accuracy of 65 m, which is more than four times the maximum value allowed by Brazilian legislation (15 m). Worse results were found for geological maps derived from 1:50,000 topographic maps (RMSE = 147 m), for which the maximum allowed value is 30 m. In most cases positional errors are of systematic origin and can be easily corrected (e.g., affine transformation). ASTER GDEM has many holes and is very noisy, making it of little use in the studied area. TOPODATA, which is SRTM kriged from originally 3 to 1 arc-second by the Brazilian National

  3. Combining satellite data with ancillary data to produce a refined land-use/land-cover map

    USGS Publications Warehouse

    Stewart, J.S.

    1998-01-01

    As part of the U.S. Geological Survey's National Water-Quality Assessment Program in the Western Lake Michigan Drainages Study Unit, a current map of land use and land cover is needed to gain a better understanding of how land use and land cover may influence water quality. Satellite data from the Landsat Thematic Mapper provides a means to map and measure the type and amount of various land-cover types across the Study Unit and can be easily updated as changes occur in the landscape or in water quality. Translating these land cover categories to land use, however, requires the use of other thematic maps or ancillary data layers, such as wetland inventories, population data, or road networks. This report describes a process of (1) using satellite imagery to produce a land-cover map for the Fox/Wolf River basin, a portion of the Western Lake Michigan Drainages NAWQA Study Unit and (2) improving the satellite-derived land-cover map by using other thematic maps. The multiple data layers are processed in a geographic information system (GIS), and the combination provides more information than individual sources alone.

  4. Using remote sensing and ancillary data to extend airborne electromagnetic resistivity surveys for regional permafrost interpretation

    NASA Astrophysics Data System (ADS)

    Pastick, N.; Wylie, B. K.; Minsley, B. J.; Jorgenson, T. T.; Ji, L.; Walvoord, M. A.; Smith, B. D.; Abraham, J. D.; Rose, J.

    2011-12-01

    landsat, and the Normalized Difference Water Index (NDWI) using band 7. The regression tree models were applied to a 6-scene landsat mosaic and ancillary data to make estimates of electrical resistivity at 0-1m and 0-2.6m depths for the entirety of Yukon Flats. Further studies will assess relationships between mapped surface resistivity and depth to permafrost measured in the field.

  5. Interaction of Ruthenium(II)-dipyridophenazine Complexes with CT-DNA: Effects of the Polythioether Ancillary Ligands

    PubMed Central

    Madureira, João; Goodfellow, Brian J.; Drew, Michael G. B.; de Jesus, Júlio Pedrosa; Félix, Vitor

    2001-01-01

    The complexes [Ru([9]aneS3)(dppz)Cl]Cl 1 and [Ru([12]aneS4)(dppz)]Cl2 2 ([9]aneS3 = 1,4,7- trithiaciclononane and [12]aneS4 = 1,4,7,10-tetrathiaciclododecane) were synthesised and fully characterised. These complexes belong to a small family of dipyridophenazine complexes with non-polypyridyl ancillary ligands . Interaction studies of these complexes with CT-DNA (UV/Vis titrations, steady-state emission and thermal denaturation) revealed their high affinity for DNA . Intercalation constants determined by UV/Vis titrations are of the same order of magnitude (106) as other dppz metallointercalators, namely [Ru(II)(bpy)2dppz]S2+. Differences between l and2 were identified by steady-state emission and thermal denaturation studies . Emission results are in accordance with structural data, which indicate how geometric distortions and different donor and/or acceptor ligand abilities affect luminescence. The possibility of noncovalent interactions between ancillary ligands and nucleobases by van der Waals contacts and H-bridges is discussed . Furthermore, complex l undergoes aquation under intra-cellular conditions and an equilibrium with the aquated form l' is attained . This behaviour may increase the diversity of available interaction modes. PMID:18475986

  6. Photocatalytic Conversion of CO2 to CO using Rhenium Bipyridine Platforms Containing Ancillary Phenyl or BODIPY Moieties

    SciTech Connect

    Andrade, Gabriel; Pistner, Allen; Yapp, Glenn P. A.; Lutterman, Daniel A; Rosenthal, Joel

    2013-01-01

    Harnessing of solar energy to drive the reduction of carbon dioxide to fuels requires the development of efficient catalysts that absorb sunlight. In this work, we detail the synthesis, electrochemistry and photophysical properties of a set of homologous fac-ReI(CO)3 complexes containing either an ancillary phenyl (8) or BODIPY (12) substituent. These studies demonstrate that both the electronic properties of the rhenium center and BODIPY chromophore are maintained for these systems. Photolysis studies demonstrate that both assemblies 8 and 12 are competent catalysts for the photochemical reduction of CO2 to CO in DMF using triethanolamine (TEOA) as a sacrificial reductant. Both these systems display TOFs for photocatalytic CO production upon irradiation with light ( ex 400 nm) of ~5 hr 1 with TON values of approximately 20. Although structural and photophysical measurements demonstrate that electronic coupling between the BODIPY and fac-ReI(CO)3 units is limited for complex 12, this work clearly shows that the photoactive BODIPY moiety is tolerated during catalysis and does not interfere with the observed photochemistry. When taken together, these results provide a clear roadmap for the development of advanced rhenium bipyridine complexes bearing ancillary BODIPY groups for the efficient photocatalytic reduction of CO2 using visible light.

  7. Photocatalytic Conversion of CO2 to CO using Rhenium Bipyridine Platforms Containing Ancillary Phenyl or BODIPY Moieties

    PubMed Central

    Andrade, Gabriel A.; Pistner, Allen J.; Yap, Glenn P.A.; Lutterman, Daniel A.; Rosenthal, Joel

    2013-01-01

    Harnessing of solar energy to drive the reduction of carbon dioxide to fuels requires the development of efficient catalysts that absorb sunlight. In this work, we detail the synthesis, electrochemistry and photophysical properties of a set of homologous fac-ReI(CO)3 complexes containing either an ancillary phenyl (8) or BODIPY (12) substituent. These studies demonstrate that both the electronic properties of the rhenium center and BODIPY chromophore are maintained for these complexes. Photolysis studies demonstrate that both assemblies 8 and 12 are competent catalysts for the photochemical reduction of CO2 to CO in DMF using triethanolamine (TEOA) as a sacrificial reductant. Both compounds 8 and 12 display TOFs for photocatalytic CO production upon irradiation with light (λex ≥ 400 nm) of ~5 hr−1 with TON values of approximately 20. Although structural and photophysical measurements demonstrate that electronic coupling between the BODIPY and fac-ReI(CO)3 units is limited for complex 12, this work clearly shows that the photoactive BODIPY moiety is tolerated during catalysis and does not interfere with the observed photochemistry. When taken together, these results provide a clear roadmap for the development of advanced rhenium bipyridine complexes bearing ancillary BODIPY groups for the efficient photocatalytic reduction of CO2 using visible light. PMID:24015374

  8. Integrated Stormwater Management in Los Angeles, California: Best Management Practices and Evaluation of Ancillary Benefits

    NASA Astrophysics Data System (ADS)

    Hogue, T. S.

    2014-12-01

    Best Management Practices (BMPs) and Low Impact Development (LID) have been the primary tools to address quantitative and qualitative surface runoff impacts. The City of Los Angeles (City) is evaluating plans for individual Total Maximum Daily Load (TMDL) pollutants in each of its major watersheds. However, it has yet to be studied if implementing individual BMP projects will adequately address water quality objectives for receiving (downstream) water bodies, such as Ballona Creek, Ballona Estuary and the Santa Monica Bay. In addition, there is significant uncertainty surrounding potential ancillary benefits (flood reduction, water supply, green space, etc.) from BMP/LID implementation. This presentation will overview our work with the City evaluating the influence of BMPs and LIDs in improving water quality at the watershed scale as well as quantifying other hydrologic benefits. Multiple BMP scenarios are considered to identify various pathways toward improved receiving water body quality in Ballona Creek and Dominquez watersheds. Specific study objectives are to: 1) identify suites of BMP scenarios which can lead to TMDL compliance, 2) quantify the multiple benefits provided by BMPs beyond their primary water quality improvement purpose, and 3) evaluate the success of using existing software for watershed-scale BMP modeling. Our goal is to provide realistic, implementable pathways that can be used by stakeholders to help plan for future education, outreach and capital improvement programs as well as determine feasible pollutant reduction objectives.

  9. Catalytic water oxidation by mononuclear Ru complexes with an anionic ancillary ligand.

    PubMed

    Tong, Lianpeng; Inge, A Ken; Duan, Lele; Wang, Lei; Zou, Xiaodong; Sun, Licheng

    2013-03-01

    Mononuclear Ru-based water oxidation catalysts containing anionic ancillary ligands have shown promising catalytic efficiency and intriguing properties. However, their insolubility in water restricts a detailed mechanism investigation. In order to overcome this disadvantage, complexes [Ru(II)(bpc)(bpy)OH2](+) (1(+), bpc = 2,2'-bipyridine-6-carboxylate, bpy = 2,2'-bipyridine) and [Ru(II)(bpc)(pic)3](+) (2(+), pic = 4-picoline) were prepared and fully characterized, which features an anionic tridentate ligand and has enough solubility for spectroscopic study in water. Using Ce(IV) as an electron acceptor, both complexes are able to catalyze O2-evolving reaction with an impressive rate constant. On the basis of the electrochemical and kinetic studies, a water nucleophilic attack pathway was proposed as the dominant catalytic cycle of the catalytic water oxidation by 1(+), within which several intermediates were detected by MS. Meanwhile, an auxiliary pathway that is related to the concentration of Ce(IV) was also revealed. The effect of anionic ligand regarding catalytic water oxidation was discussed explicitly in comparison with previously reported mononuclear Ru catalysts carrying neutral tridentate ligands, for example, 2,2':6',2″-terpyridine (tpy). When 2(+) was oxidized to the trivalent state, one of its picoline ligands dissociated from the Ru center. The rate constant of picoline dissociation was evaluated from time-resolved UV-vis spectra. PMID:23409776

  10. A hybrid-systems approach to spin squeezing using a highly dissipative ancillary system

    NASA Astrophysics Data System (ADS)

    Dooley, Shane; Yukawa, Emi; Matsuzaki, Yuichiro; Knee, George C.; Munro, William J.; Nemoto, Kae

    2016-05-01

    Squeezed states of spin systems are an important entangled resource for quantum technologies, particularly quantum metrology and sensing. Here we consider the generation of spin squeezed states by interacting the spins with a dissipative ancillary system. We show that spin squeezing can be generated in this model by two different mechanisms: one-axis twisting (OAT) and driven collective relaxation (DCR). We can interpolate between the two mechanisms by simply adjusting the detuning between the dissipative ancillary system and the spin system. Interestingly, we find that for both mechanisms, ancillary system dissipation need not be considered an imperfection in our model, but plays a positive role in spin squeezing. To assess the feasibility of spin squeezing we consider two different implementations with superconducting circuits. We conclude that it is experimentally feasible to generate a squeezed state of hundreds of spins either by OAT or by DCR.

  11. Ancillary services in the health care industry: is Six Sigma reasonable?

    PubMed

    Johnstone, Peter A S; Hendrickson, Julie A W; Dernbach, Allison J; Secord, Ann R; Parker, John C; Favata, Michael A; Puckett, Michael L

    2003-01-01

    Within the naval medical center construct, the disparate disciplines encompassed within ancillary services lend themselves to formal quality analysis and process improvement. This analysis uses the Six Sigma approach. Error rates were investigated and calculated for various processes within ancillary services at Naval Medical Center, San Diego. These were translated into the common metric of defects per million opportunities (DPMO). DPMO rates vary between 21.5 and 420,000. These correspond to Sigma values from 1.7 to approaching 6. Rates vary with biological complexity of the system and the degree of automation available. Some ancillary services translate well into a Six Sigma schema. Systems with high potential patient risk if performed poorly and those amenable to second checking and computer oversight may be candidates for such optimization. This should be undertaken in a local environment conducive to individual error reporting, and in a corporate environment with the will and funding to support the transition. PMID:12593375

  12. Effects of ancillary ligands on selectivity of protein labeling with platinum(II) chloro complexes

    SciTech Connect

    Zhou, Xia-Ying.

    1990-02-01

    Potassium (2,6-pyridinedicarboxylato)chloroplatinate(II) was synthesized. The molecular structure of the complex in (n-Bu){sub 4}N(Pt(dipic)Cl){center dot}0.5H{sub 2}O was determined by x-ray crystallography. The (Pt(dipic)Cl){sup {minus}} is essentially planar and contains a Pt(II) atom, a tridentate dipicolinate dianion ligand, and a unidentate Cl{sup {minus}} ligand. The bis(bidentate) complex trans-(Pt(dipic){sub 2}){sup 2{minus}} was also observed by {sup 1}H NMR. A red gel-like substance was observed when the yellow aqueous solution of K(Pt(dipic)Cl) was cooled or concentrated. The K(Pt(dipic)Cl) molecules form stacks in the solid state and gel-like substance but remain monomeric over a wide range of concentrations and temperatures. The reactivity and selectivity of(Pt(dipic)Cl){sup {minus}} toward cytochromes c from horse and tuna were studied. The new transition-metal reagent is specific for methionine residues. Di(2-pyridyl-{beta}-ethyl)sulfidochloroplatinum(II) chloride dihydrate was also synthesized. This complex labels histidine and methionine residues in cytochrome c. The ancillary ligands in these platinum(II) complexes clearly determine the selectivity of protein labeling. 106 refs., 10 figs., 11 tabs.

  13. Disaggregating Census Data for Population Mapping Using Random Forests with Remotely-Sensed and Ancillary Data

    PubMed Central

    Stevens, Forrest R.; Gaughan, Andrea E.; Linard, Catherine; Tatem, Andrew J.

    2015-01-01

    High resolution, contemporary data on human population distributions are vital for measuring impacts of population growth, monitoring human-environment interactions and for planning and policy development. Many methods are used to disaggregate census data and predict population densities for finer scale, gridded population data sets. We present a new semi-automated dasymetric modeling approach that incorporates detailed census and ancillary data in a flexible, “Random Forest” estimation technique. We outline the combination of widely available, remotely-sensed and geospatial data that contribute to the modeled dasymetric weights and then use the Random Forest model to generate a gridded prediction of population density at ~100 m spatial resolution. This prediction layer is then used as the weighting surface to perform dasymetric redistribution of the census counts at a country level. As a case study we compare the new algorithm and its products for three countries (Vietnam, Cambodia, and Kenya) with other common gridded population data production methodologies. We discuss the advantages of the new method and increases over the accuracy and flexibility of those previous approaches. Finally, we outline how this algorithm will be extended to provide freely-available gridded population data sets for Africa, Asia and Latin America. PMID:25689585

  14. Synthesis, characterization and properties of copper(I) complexes with bis(diphenylphosphino)-ferrocene ancillary ligand

    NASA Astrophysics Data System (ADS)

    Liu, Xinfang; Zhang, Songlin; Ding, Yuqiang

    2012-06-01

    Three copper(I) complexes (2-4) containing dppf ancillary ligand (dppf = bis(diphenylphosphino)-ferrocene) were synthesized when chloride-bridged copper(I) complex 1 reacted with acetanilide and characterized by IR, element analysis and NMR spectrum. And the crystal structures of complexes 2 and 4 have been determined by X-ray diffraction method. Complex 2, an acetate-bridged copper(I) complex, was obtained under N2 atmosphere in un-dried solvent; the acetate ion came from the hydrolysis reaction of acetanilide due to residual water in solvent. Acetanilide was deprotonated and coordinated with the copper(I) centre to form a copper(I) amidate complex 3 when reacted in pre-dried solvent. In addition, a known complex 4, the oxidation product of dppf, was isolated from the same reaction system when reacted in air atmosphere. CV and TG experiments were carried out to check the electron transfer properties and thermal stabilities of complexes 2-3. Finally, the arylation reaction of complex 3 with iodobenzene was performed to study the reaction mechanism of copper(I) catalyzed Goldberg reaction.

  15. Disaggregating census data for population mapping using random forests with remotely-sensed and ancillary data.

    PubMed

    Stevens, Forrest R; Gaughan, Andrea E; Linard, Catherine; Tatem, Andrew J

    2015-01-01

    High resolution, contemporary data on human population distributions are vital for measuring impacts of population growth, monitoring human-environment interactions and for planning and policy development. Many methods are used to disaggregate census data and predict population densities for finer scale, gridded population data sets. We present a new semi-automated dasymetric modeling approach that incorporates detailed census and ancillary data in a flexible, "Random Forest" estimation technique. We outline the combination of widely available, remotely-sensed and geospatial data that contribute to the modeled dasymetric weights and then use the Random Forest model to generate a gridded prediction of population density at ~100 m spatial resolution. This prediction layer is then used as the weighting surface to perform dasymetric redistribution of the census counts at a country level. As a case study we compare the new algorithm and its products for three countries (Vietnam, Cambodia, and Kenya) with other common gridded population data production methodologies. We discuss the advantages of the new method and increases over the accuracy and flexibility of those previous approaches. Finally, we outline how this algorithm will be extended to provide freely-available gridded population data sets for Africa, Asia and Latin America. PMID:25689585

  16. Benthic macrofauna and ancillary data for San Francisco Bay, California, March to November 1987

    USGS Publications Warehouse

    Schemel, Laurence E.; Ota, Allan Y.; Harmon, J.G.; Shay, J.M.; Adorado, R.N.

    1988-01-01

    Benthic macrofauna and ancillary data were collected during 1987 as part of the U.S. Geological Survey Regional Effects Monitoring Program in San Francisco Bay, California. Data were collected during five cruises at 2-month intervals from March through November. Benthic macrofauna for identification of species and sediment for size analysis were sampled at eight stations. Ancillary data, which consisted of salinity, temperature, dissolved-oxygen concentrations, and suspended sediment, were collected at 12 stations. Salinity and temperature were measured at three stations that coincided with continuous water quality monitors. Abundances and geographical distributions of a newly introduced species of clam were measured. (USGS)

  17. 77 FR 40413 - Third-Party Provision of Ancillary Services; Accounting and Financial Reporting for New Electric...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... Organized Wholesale Energy Markets, Order No. 745, 76 FR 16658 (Mar. 24, 2011), FERC Stats. & Regs. ] 31,322... 101 Third-Party Provision of Ancillary Services; Accounting and Financial Reporting for New Electric... 101 Third-Party Provision of Ancillary Services; Accounting and Financial Reporting for New...

  18. Regulatory issues associated with closure of the Hanford AX Tank Farm ancillary equipment

    SciTech Connect

    Becker, D.L.

    1998-09-02

    Liquid mixed, high-level radioactive waste has been stored in underground single-shell tanks at the US Department of Energy`s (DOE`s) Hanford Site. After retrieval of the waste from the single-shell tanks, the DOE will proceed with closure of the tank farm. The 241-AX Tank Farm includes four one-million gallon single-shell tanks in addition to sluice lines, transfer lines, ventilation headers, risers, pits, cribs, catch tanks, buildings, well and associated buried piping. This equipment is classified as ancillary equipment. This document addresses the requirements for regulatory close of the ancillary equipment in the Hanford Site 241-AX Tank Farm. The options identified for physical closure of the ancillary equipment include disposal in place, disposal in place after treatment, excavation and disposal on site in an empty single-shell tank, and excavation and disposal outside the AX Tank Farm. The document addresses the background of the Hanford Site and ancillary equipment in the AX Tank Farm, regulations for decontamination and decommissioning of radioactively contaminated equipment, requirements for the cleanup and disposal of radioactive wastes, cleanup and disposal requirements governing hazardous and mixed waste, and regulatory requirements and issues associated with each of the four physical closure options. This investigation was conducted by the Sandia National Laboratories, Albuquerque, New Mexico, during Fiscal Year 1998 for the Hanford Tanks Initiative Project.

  19. GLOBAL CHANGE RESEARCH NEWS #15: WORKSHOP ON ANCILLARY BENEFITS AND COSTS OF CLIMATE CHANGE STRATEGIES

    EPA Science Inventory

    EPA's Global Change Research Program is co-sponsoring a three-day workshop to examine possible ancillary benefits of climate change adaptation and mitigation policies. The goals of the workshop are: (1)to establish a common basis of understanding about the conceptual and empiric...

  20. Risk Management: Supporting the District's Ancillary Services Staff

    ERIC Educational Resources Information Center

    Waldmann, Steve; Strasburger, Tom

    2013-01-01

    The everyday operations of a school district depend on a network of people, including students, teachers, staff, and administrators. However, the ancillary services staff are really responsible for making the school day run smoothly. They are often the first employees that students see in the morning, either on the school bus or in the cafeteria,…

  1. Improving the Quality of Ability Estimates through Multidimensional Scoring and Incorporation of Ancillary Variables

    ERIC Educational Resources Information Center

    de la Torre, Jimmy

    2009-01-01

    For one reason or another, various sources of information, namely, ancillary variables and correlational structure of the latent abilities, which are usually available in most testing situations, are ignored in ability estimation. A general model that incorporates these sources of information is proposed in this article. The model has a general…

  2. 30 CFR 550.207 - What ancillary activities may I conduct?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What ancillary activities may I conduct? 550.207 Section 550.207 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR... cuttings discharges, projected air emissions, or potential hydrogen sulfide (H2S) releases....

  3. 30 CFR 250.207 - What ancillary activities may I conduct?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What ancillary activities may I conduct? 250.207 Section 250.207 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT... spills, drilling muds and cuttings discharges, projected air emissions, or potential hydrogen...

  4. 30 CFR 550.207 - What ancillary activities may I conduct?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What ancillary activities may I conduct? 550.207 Section 550.207 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR... cuttings discharges, projected air emissions, or potential hydrogen sulfide (H2S) releases....

  5. 47 CFR 90.317 - Fixed ancillary signaling and data transmissions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Fixed ancillary signaling and data transmissions. 90.317 Section 90.317 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Authorization in the Band 470-512 MHz...

  6. 47 CFR 90.317 - Fixed ancillary signaling and data transmissions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Fixed ancillary signaling and data transmissions. 90.317 Section 90.317 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Authorization in the Band 470-512 MHz...

  7. 47 CFR 90.317 - Fixed ancillary signaling and data transmissions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Fixed ancillary signaling and data transmissions. 90.317 Section 90.317 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Authorization in the Band 470-512 MHz...

  8. 47 CFR 90.317 - Fixed ancillary signaling and data transmissions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Fixed ancillary signaling and data transmissions. 90.317 Section 90.317 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Authorization in the Band 470-512 MHz...

  9. 47 CFR 90.317 - Fixed ancillary signaling and data transmissions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Fixed ancillary signaling and data transmissions. 90.317 Section 90.317 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Authorization in the Band 470-512 MHz...

  10. Advanced technology for ancillary coal cleaning operations. Technical progress report, September--December, 1987

    SciTech Connect

    Not Available

    1994-09-01

    The work under contract number DE-AC22-87PC97881 is devoted to experimental research and development to investigate the feasibility of novel ancillary coal-cleaning technologies that offer a potential for reduced capital and operating costs. The ancilliary operations that are specifically addressed in this work include pulse enhanced drying, fines reconstitution by extrusion, and hydraulic wave comminution.

  11. Four homochiral coordination polymers contain N-acetyl-L-tyrosine and different N-donor ligand: Influence of metal cations, ancillary ligands and coordination modes

    NASA Astrophysics Data System (ADS)

    Li, Meng-Li; Song, Hui-Hua

    2013-10-01

    Using the chiral ligand N-acetyl-L-tyrosine (Hacty) and maintaining identical reaction conditions, Zn(II), Co(II), and Cd(II) salts provided four novel homochiral coordination polymers {[Zn(acty)(bipy)2(H2O)2]·NO3·2H2O}n1, {[Co(acty)(bipy)2(H2O)2]·NO3·2H2O}n2, {[Cd(acty)2(bipy)H2O]·H2O}n3, and {[Cd(acty)(bpe)2(Ac)]·6H2O}n4 (bipy=4,4‧-bipyridine; bpe=1,2-di(4-pyridyl)ethane) in the presence of ancillary ligands. Compounds 1 and 2 are isostructural 1D chain structures. The neighboring chains are further linked into a 3D supramolecular structure via π⋯π stacking and hydrogen bond interactions. Compound 3 shows a 2D network and 4 generates 1D infinite chains along the c-axis. Compounds 3 and 4 are further connected into 3D supramolecular network by hydrogen bond interactions. More importantly, coordination in acyl oxygen atoms and ancillary ligands (bpe) as monodentate decorating ligands in 4 are rarely reported. Ancillary ligands and metal cations significantly influence the structure of the complexes. The photoluminescence properties of 1, 3, and 4 were studied at room temperature. Circular dichroism (CD) of the complexes have been investigated.

  12. Reduction of CO2 using a Rhenium Bipyridine Complex Containing Ancillary BODIPY Redox Reservoirs

    SciTech Connect

    Teesdale, Justin; Pistner, Allen; Yapp, Glenn P. A.; Ma, Yingzhong; Lutterman, Daniel A; Rosenthal, Joel

    2014-01-01

    The reduction of carbon dioxide to chemical fuels such as carbon monoxide is an important challenge in the field of renewable energy conversion. Given the thermodynamic stability of carbon dioxide, it is difficult to efficiently activate this substrate in a selective fashion and the development of new electrocatalysts for CO2 reduction is of prime importance. To this end, we have prepared and studied a new fac-ReI(CO)3 complex supported by a bipyridine ligand containing ancillary BODIPY moieties ([Re(BB2)(CO)3Cl]). Voltammetry experiments revealed that this system displays a rich redox chemistry under N2, as [Re(BB2)(CO)3Cl] can be reduced by up to four electrons at modest potentials. These redox events have been characterized as the ReI/0 couple, and three ligand based reductions two of which are localized on the BODIPY units. The ability of the BB2 ligand to serve as a noninnocent redox reservoir is manifest in an enhanced electrocatalysis with CO2 as compared to an unsubstituted Re-bipyridine complex lacking BODIPY units ([Re(bpy)(CO)3Cl]). The second order rate constant for reduction of CO2 by [Re(BB2)(CO)3Cl] was measured to be k = 3400 M 1s 1 at an applied potential of 2.0 V versus SCE, which is roughly three times greater than the corresponding unsubstituted Re-bipyridine homologue. Photophysical and photochemical studies were also carried out to determine if [Re(BB2)(CO)3Cl] was a competent platform for CO2 reduction using visible light. These experiments showed that this complex supports unusual excited state dynamics that are not typically observed for fac- ReI(CO)3 complexes.

  13. Ruthenium(II) polypyridyl complexes with hydrophobic ancillary ligand as Aβ aggregation inhibitors.

    PubMed

    Vyas, Nilima A; Ramteke, Shefali N; Kumbhar, Avinash S; Kulkarni, Prasad P; Jani, Vinod; Sonawane, Uddhavesh B; Joshi, Rajendra R; Joshi, Bimba; Erxleben, Andrea

    2016-10-01

    The synthesis, spectral and electrochemical characterization of the complexes of the type [Ru(NN)2(txbg)](2+) where NN is 2,2'-bipyridine (bpy) (1), 1,10-phenanthroline (phen) (2), dipyrido [3,2-d:2',3f] quinoxaline (dpq) (3), and dipyrido[3,2-a:2',3'-c]phenazine (dppz) (4) which incorporate the tetra-xylene bipyridine glycoluril (txbg) as the ancillary ligand are described in detail. Crystal structures of ligand txbg and complex 2 were solved by single crystal X-ray diffraction. Thioflavin T (ThT) fluorescence and Transmission Electron Microscopy (TEM) results indicated that at micromolar concentration all complexes exhibit significant potential of Aβ aggregation inhibition, while the ligand txbg displayed weak activity towards Aβ aggregation. Complex 1 showed relatively low inhibition (70%) while complexes 2-4 inhibited nearly 100% Aβ aggregation after 240 h of incubation. The similar potential of complexes 2-4 and absence of any trend in their activity with the planarity of polypyridyl ligands suggests there is no marked effect of planarity of coligands on their inhibitory potential. Further studies on acetylcholinesterase (AChE) inhibition indicated very weak activity of these complexes against AChE. Detailed interactions of Aβ with both ligand and complex 2 have been studied by molecular modeling. Complex 2 showed interactions involving all three polypyridyl ligands with hydrophobic region of Aβ. Furthermore, the toxicity of these complexes towards human neuroblastoma cells was evaluated by MTT assay and except complex 4, the complexes displayed very low toxicity. PMID:27406812

  14. Reduction of CO2 using a Rhenium Bipyridine Complex Containing Ancillary BODIPY Moieties.

    PubMed

    Teesdale, Justin J; Pistner, Allen J; Yap, Glenn P A; Ma, Ying-Zhong; Lutterman, Daniel A; Rosenthal, Joel

    2014-04-15

    The reduction of carbon dioxide to chemical fuels such as carbon monoxide is an important challenge in the field of renewable energy conversion. Given the thermodynamic stability of carbon dioxide, it is difficult to efficiently activate this substrate in a selective fashion and the development of new electrocatalysts for CO2 reduction is of prime importance. To this end, we have prepared and studied a new fac-Re(I)(CO)3 complex supported by a bipyridine ligand containing ancillary BODIPY moieties ([Re(BB2)(CO)3Cl]). Voltammetry experiments revealed that this system displays a rich redox chemistry under N2, as [Re(BB2)(CO)3Cl] can be reduced by up to four electrons at modest potentials. These redox events have been characterized as the Re(I/0) couple, and three ligand based reductions - two of which are localized on the BODIPY units. The ability of the BB2 ligand to serve as a non-innocent redox reservoir is manifest in an enhanced electrocatalysis with CO2 as compared to an unsubstituted Re-bipyridine complex lacking BODIPY units ([Re(bpy)(CO)3Cl]). The second order rate constant for reduction of CO2 by [Re(BB2)(CO)3Cl] was measured to be k = 3400 M(-1)s(-1) at an applied potential of -2.0 V versus SCE, which is roughly three times greater than the corresponding unsubstituted Re-bipyridine homologue. Photophysical and photochemical studies were also carried out to determine if [Re(BB2)(CO)3Cl] was a competent platform for CO2 reduction using visible light. These experiments showed that this complex supports unusual excited state dynamics that precludes efficient CO2 reduction and are distinct from those that are typically observed for fac-Re(I)(CO)3 complexes. PMID:25395735

  15. Reduction of CO2 using a Rhenium Bipyridine Complex Containing Ancillary BODIPY Moieties

    PubMed Central

    Teesdale, Justin J.; Pistner, Allen J.; Yap, Glenn P.A.; Ma, Ying-Zhong; Lutterman, Daniel A.; Rosenthal, Joel

    2014-01-01

    The reduction of carbon dioxide to chemical fuels such as carbon monoxide is an important challenge in the field of renewable energy conversion. Given the thermodynamic stability of carbon dioxide, it is difficult to efficiently activate this substrate in a selective fashion and the development of new electrocatalysts for CO2 reduction is of prime importance. To this end, we have prepared and studied a new fac-ReI(CO)3 complex supported by a bipyridine ligand containing ancillary BODIPY moieties ([Re(BB2)(CO)3Cl]). Voltammetry experiments revealed that this system displays a rich redox chemistry under N2, as [Re(BB2)(CO)3Cl] can be reduced by up to four electrons at modest potentials. These redox events have been characterized as the ReI/0 couple, and three ligand based reductions – two of which are localized on the BODIPY units. The ability of the BB2 ligand to serve as a non-innocent redox reservoir is manifest in an enhanced electrocatalysis with CO2 as compared to an unsubstituted Re-bipyridine complex lacking BODIPY units ([Re(bpy)(CO)3Cl]). The second order rate constant for reduction of CO2 by [Re(BB2)(CO)3Cl] was measured to be k = 3400 M−1s−1 at an applied potential of −2.0 V versus SCE, which is roughly three times greater than the corresponding unsubstituted Re-bipyridine homologue. Photophysical and photochemical studies were also carried out to determine if [Re(BB2)(CO)3Cl] was a competent platform for CO2 reduction using visible light. These experiments showed that this complex supports unusual excited state dynamics that precludes efficient CO2 reduction and are distinct from those that are typically observed for fac-ReI(CO)3 complexes. PMID:25395735

  16. Diode-pumped ytterbium-doped phosphate and tungstate regenerative amplifiers and ancillary investigations

    NASA Astrophysics Data System (ADS)

    Liu, Hsiao-Hua

    This thesis focuses on the development of directly diode- pumped solid-state regenerative laser amplifiers. Our purpose is to build a compact, simple, reliable, and economical subpicosecond laser system by employing a direct diode-pumping scheme for real-world applications such as medical surgeries and micromachining. Ytterbium- doped phosphate glass (QX/Yb) and ytterbium-doped tungstate crystals (Yb:KYW and Yb:KGW) are used as the amplifier gain media, and their laser properties are discussed and compared with other ytterbium-doped materials. The same oscillator, stretcher, and compressor are used with each amplifier presented. Both end- and side-pumping configurations are implemented and compared wherever possible. Typically, an end-pumped laser has a higher efficiency, whereas a side-pumped laser has a simpler, and thus more compact setup. To improve the efficiency of a side-pumped laser, we have proposed and demonstrated a novel pumping scheme with the QX/Yb, amplifier. To match the elliptical beam from the pump diodes, we have designed and built cavities with an elliptical fundamental mode by using cylindrical optics. Millijoule, subpicosecond pulses have been produced from our QX/Yb regenerative amplifier using the proposed pumping scheme and an elliptic-mode cavity. The diode- pumped ytterbium-doped tungstate regenerative amplifiers in this thesis produced subpicosecond pulses with at least tens of microjoules of pulse energy at a kHz repetition rate, also using a cavity with an elliptical fundamental mode. A self-starting Kerr-lens mode-locked Yb:KYW oscillator directly pumped by diodes and a low- repetition-rate Yb:KGW regenerative amplifier pumped by a flashlamp-pumped Ti:sapphire laser are also presented as ancillary studies.

  17. The new Heavy-ion MCP-based Ancillary Detector DANTE for the CLARA-PRISMA Setup

    SciTech Connect

    Valiente-Dobon, J. J.; Gadea, A.; Corradi, L.; De Angelis, G.; Della Vedova, F.; Fioretto, E.; Marginean, N.; Napoli, D. R.; Orlandi, R.; Pokrovsky, I.; Sahin, E.; Stefanini, A. M.; Brambilla, S.; Kondratiev, N. A.; Kozulin, E. M.; Beghini, S.; Farnea, E.; Lunardi, S.; Montagnoli, G.; Ur, C. A.

    2006-08-14

    The CLARA-PRISMA setup is a powerful tool for spectroscopic studies of neutron-rich nuclei produced in multi-nucleon transfer and deep-inelastic reactions. It combines the large acceptance spectrometer PRISMA with the {gamma}-ray array CLARA. At present, the ancillary heavy-ion detector DANTE, based on Micro-Channel Plates to be installed at the CLARA-PRISMA setup, is being constructed at LNL. DANTE will open the possibility of measuring {gamma}-{gamma} Doppler-corrected coincidences for the events outside the acceptance of PRISMA. In this presentation, it is described the heavy-ion detector DANTE, as well as the performances of the first prototype.

  18. Four homochiral coordination polymers contain N-acetyl-L-tyrosine and different N-donor ligand: Influence of metal cations, ancillary ligands and coordination modes

    SciTech Connect

    Li, Meng-Li; Song, Hui-Hua

    2013-10-15

    Using the chiral ligand N-acetyl-L-tyrosine (Hacty) and maintaining identical reaction conditions, Zn(II), Co(II), and Cd(II) salts provided four novel homochiral coordination polymers ([Zn(acty)(bipy){sub 2}(H{sub 2}O){sub 2}]·NO{sub 3}·2H{sub 2}O){sub n}1, ([Co(acty)(bipy){sub 2}(H{sub 2}O){sub 2}]·NO{sub 3}·2H{sub 2}O){sub n}2, ([Cd(acty){sub 2}(bipy)H{sub 2}O]·H{sub 2}O){sub n}3, and ([Cd(acty)(bpe){sub 2}(Ac)]·6H{sub 2}O){sub n}4 (bipy=4,4′-bipyridine; bpe=1,2-di(4-pyridyl)ethane) in the presence of ancillary ligands. Compounds 1 and 2 are isostructural 1D chain structures. The neighboring chains are further linked into a 3D supramolecular structure via π⋯π stacking and hydrogen bond interactions. Compound 3 shows a 2D network and 4 generates 1D infinite chains along the c-axis. Compounds 3 and 4 are further connected into 3D supramolecular network by hydrogen bond interactions. More importantly, coordination in acyl oxygen atoms and ancillary ligands (bpe) as monodentate decorating ligands in 4 are rarely reported. Ancillary ligands and metal cations significantly influence the structure of the complexes. The photoluminescence properties of 1, 3, and 4 were studied at room temperature. Circular dichroism (CD) of the complexes have been investigated. - Graphical abstract: Four new homochiral coordination polymers were prepared and structurally characterized, which investigate the influence of the ancillary ligands and metal ions on the design and synthesis of coordination polymers. Display Omitted - Highlights: • It is rarely reported that the chiral coordination polymers prepared with N-acetyl-L-tyrosine ligands. • The alkalescent acetyl oxygen atom is difficult to participate in coordination but it is happened in the N-acetyl-L-tyrosine ligands. • The ancillary ligands (4,4′-bipy and bpe) are present in an unusual coordination modes, monodentate decorating ligands in 1, 2 and 4. • Structure comparative analyses results indicate that the

  19. Summary of the 1993 ASHG ancillary meeting recent research on chromosome 4p syndromes and genes

    SciTech Connect

    Estabrooks, L.L.; Breg, W.R.; Hayden, M.R.

    1995-02-13

    The following is a summary of presentations given during an ancillary meeting to the 1993 American Society of Human Genetics Meeting in New Orleans, LA. This ancillary meeting, entitled Recent Research on Chromosome 4p Syndromes and Genes, reviewed the history of the Wolf-Hirschhorn syndrome (WHS), the natural history of patients with WHS, and the smallest region of deletion associated with the WHS. The proximal 4p deletion syndrome and the duplication 4p syndrome were also described and advice was offered regarding detection of chromosome 4p deletions, duplications, and rearrangements. The current status of the physical map of chromosome 4p with emphasis on the genes that map to the 4p16 region was presented along with a preliminary phenotypic map of 4p16. The goal of this format was to provide a comprehensive review of the clinical presentations, diagnostic capabilities, and genetic mapping advances involving chromosome 4p.

  20. Organizational boundaries of medical practice: the case of physician ownership of ancillary services

    PubMed Central

    2012-01-01

    Physician ownership of in-office ancillary services (IOASs) has come under increasing scrutiny. Advocates of argue that IOASs allow physicians to supervise the quality and coordination of care. Critics have argued that IOASs create financial incentives for physicians to increase ancillary service volume. In this paper we develop a conceptual framework to evaluate the tradeoffs associated with physician ownership of IOASs. There is some evidence supporting the existence of scope and transaction economies in IOASs. Improvement in flow and continuity of care are likely to generate scope economies and improvements in quality monitoring and reductions in consumer transaction costs are likely to generate transaction economies. Other factors include the capture of upstream and downstream profits, but these incentives are likely to be small compared to scope and transaction economies. Policy debates on the merits of IOASs should include an explicit assessment of these tradeoffs. This research was supported in part by funding from the American Association of Orthopaedic Surgeons (AAOS). PMID:22828324

  1. Ancillary qubit spectroscopy of vacua in cavity and circuit quantum electrodynamics.

    PubMed

    Lolli, Jared; Baksic, Alexandre; Nagy, David; Manucharyan, Vladimir E; Ciuti, Cristiano

    2015-05-01

    We investigate theoretically how the spectroscopy of an ancillary qubit can probe cavity (circuit) QED ground states containing photons. We consider three classes of systems (Dicke, Tavis-Cummings, and Hopfield-like models), where nontrivial vacua are the result of ultrastrong coupling between N two-level systems and a single-mode bosonic field. An ancillary qubit detuned with respect to the boson frequency is shown to reveal distinct spectral signatures depending on the type of vacua. In particular, the Lamb shift of the ancilla is sensitive to both ground state photon population and correlations. Backaction of the ancilla on the cavity ground state is investigated, taking into account the dissipation via a consistent master equation for the ultrastrong coupling regime. The conditions for high-fidelity measurements are determined. PMID:26001000

  2. Defining extreme wildland fires using geospatial and ancillary metrics

    NASA Astrophysics Data System (ADS)

    Lannom, K. O.; Tinkham, W.; Smith, A. M.; Abatzoglou, J. T.; Newingham, B. A.; Hall, T. E.; Morgan, P.; Strand, E. K.; Paveglio, T. B.; Anderson, J. W.

    2013-12-01

    Mega-fires, conflagrations, extreme, and catastrophic are descriptors interchangeably used to increasingly describe fires in recent decades in the US and globally. It is necessary to have consistent, meaningful, and quantitative metrics to define these perceived 'extreme' fires, given studies predict an increased frequency of large and intense wildfires in many ecosystems as a response to climate change. This study explored four metrics to describe both widespread fire years and potentially extreme individual fires derived from a case study of wildland fires from 1984-2009 in the northwestern United States. A combination of percentile-based thresholds was used for each of the metrics to define individual fires as extreme events. We identified both widespread fire years and individual fires as potentially extreme during 1984-2009 across a 91.2 million-ha area in the northwestern United States. The metrics included distributions of fire size, fire duration, burn severity, and distance to the wildland urban interface. Widespread fire years for the study region included 1988, 2000, 2006, and 2007. When considering the intersection of all four metrics using distributions at the 90th percentile, less than 1.5% of all fires were identified as potentially extreme fires. At the more stringent 95th and 99th percentiles, this percentage reduced to less than 0.5% and 0.05% respectively.

  3. Improved Sea Surface Salinity Retrievals using Ancillary data for Aquarius Ocean Roughness Correction

    NASA Astrophysics Data System (ADS)

    Jones, L.; Hejazin, Y.; Rabollii, M.

    2012-12-01

    The Aquarius/SAC-D sea surface salinity (SSS) measurement mission was launched into polar orbit during the summer of 2011. The prime sensor is a combined L-band radiometer/scatterometer developed jointly by NASA Goddard Space Flight Center and the Jet Propulsion Laboratory, which derives SSS from ocean surface brightness temperature (Tb) measurements. This paper deals with a method of improving AQ SSS by making a making an ocean roughness brightness temperature correction (ΔTbr). The ΔTbr is derived using several ancillary data sources of surface wind measurements, namely; NOAA numerical weather model - Global Data Assimilation System (GDAS), WindSat ocean vector wind, and the CONAE Microwave Radiometer (MWR). The basis of the correction is the excess (warming) brightness temperature that is produced when the ocean is roughened by the surface wind. We model the increase in L-band Tb as a function of wind speed and direction relative to the antenna azimuth look direction. Our radiative transfer model by El-Nimri [2010] has been tuned to actual AQ ocean surface Tb's with corresponding surface wind vector. Using this ocean emissivity model and the ancillary wind vector, we derive the roughness correction, ΔTbr, which is applied to the AQ measured ocean surface Tb before retrieving SSS. Finally the effect of ΔTbr is evaluated by computing the difference between the HYCOM ocean salinity model and the AQ retrievals. These differences are cross correlated with the ancillary surface wind vector to assess the effectiveness of the roughness correction. Finally, we compare our ΔTbr with the AQ scatterometer derived ΔTbr. We compare the similarities and differenced versus the ancillary surface wind speed. S. El-Nimri et al., 2010, "An improved C-band ocean surface emissivity model at hurricane force wind speeds over a wide range of earth incidence angles," IEEE Geosci. Rem. Sens. Letters, vol. 7, NO. 4, October.

  4. Recovery Act Weekly Video: 200 Area Asbestos Removal, U-Ancillary Demolition, 200 West Transfer Building Footings

    ScienceCinema

    None

    2012-06-14

    A weekly update of the Recovery Act at work. Demolition of U-Ancillary that was contaminated with uranium and asbestos as well as removing asbestos from the Steam Generation Plant in the 200 East Area.

  5. Recovery Act Weekly Video: 200 Area Asbestos Removal, U-Ancillary Demolition, 200 West Transfer Building Footings

    SciTech Connect

    2010-01-01

    A weekly update of the Recovery Act at work. Demolition of U-Ancillary that was contaminated with uranium and asbestos as well as removing asbestos from the Steam Generation Plant in the 200 East Area.

  6. Distributed Smart Grid Asset Control Strategies for Providing Ancillary Services

    SciTech Connect

    Kalsi, Karanjit; Zhang, Wei; Lian, Jianming; Marinovici, Laurentiu D.; Moya, Christian; Dagle, Jeffery E.

    2013-10-30

    implementing real load control programs. The promise of autonomous, Grid Friendly™ response by smart appliances in the form of under-frequency load shedding was demonstrated in the GridWise Olympic Peninsula Demonstration in 2006. Each controller monitored the power grid voltage signal and requested that electrical load be shed by its appliance whenever electric power-grid frequency fell below 59.95 Hz. The controllers and their appliances responded reliably to each shallow under-frequency event, which was an average of one event per day and shed their loads for the durations of these events. Another objective of this project was to perform extensive simulation studies to investigate the impact of a population of Grid Friendly™ Appliances (GFAs) on the bulk power system frequency stability. The GFAs considered in this report are represented as demonstration units with water heaters individually modeled.

  7. The effect of spatial scale and ancillary datasets on the evaluations of EO soil moisture products

    NASA Astrophysics Data System (ADS)

    Doubkova, Marcela; Hegyova, Alena; Bloeschl, Guenter; van Dijk, Albert; Fernàndez Prieto, Diego

    2013-04-01

    With this presentation we follow up on the results of our previous paper that assessed the quality of the ASAR GM 1 km soil moisture product with the use of AWRA-L landscape hydrological model at 1 km scale. In that paper we concluded that that RMSE and R can be predicted with use of the error assessment of ASAR GM solely. The goal of this presentation is to study a) if and how do the results of the absolute and relative evaluation measures change with spatial scale, b) if the conclusion introduced in the previous paper holds independent of scale, and c) where do the differences between different relative and absolute evaluation measures stem from. The continental average absolute evaluation measures over Australia ranged between 2.65 % (Error Propagation (EP)) and 8.44 % (RMSE) of saturated soil moisture. The relative evaluation measures spanned from 0.39 (Spearman Correlation coefficient (RS) when computed with AWRA-L SSM) to 0.57 (RS when computed with GLDAS dataset). Clearly, the results varied between different absolute and different relative evaluation techniques and were as well influenced by the selection of the ancillary dataset. As expected, RS and R corresponded and demonstrated significantly different spatial patterns to any of the absolute measures. Surprisingly, however, the spatial patterns of the EP significantly differed from RMSE at 5 km scale. This is in contrary result to the similar analyses performed at 1 km scale (Doubková et al., 2012) and suggests that the selection of spatial scale has an important impact on the evaluation results. The findings and suggestions originating from the discussion are transferable to other satellite-derived soil moisture data. Of special interest is its transfer to data from the planned Sentinel-1 SAR sensor that shares similar technical characteristics but has an improved retrieval error comparable to the ASAR GM sensor. The operationally available medium resolution soil moisture from Sentinel-1 with a well

  8. Molecular Structure Laboratory. Fourier Transform Nuclear Magnetic Resonance (FTNMR) Spectrometer and Ancillary Instrumentation at SUNY Geneseo

    SciTech Connect

    Geiger, David K

    2015-12-31

    An Agilent 400-MR nuclear magnetic resonance (NMR) spectrometer and ancillary equipment were purchased, which are being used for molecular structure elucidation.  The instrumentation is housed in a pre-existing facility designed specifically for its use. This instrument package is being used to expand the research and educational efforts of the faculty and students at SUNY-Geneseo and is made available to neighboring educational institutions and business concerns.  Funds were also used for training of College personnel, maintenance of the instrumentation, and installation of the equipment.

  9. Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression.

    PubMed

    Vennin, Claire; Herrmann, David; Lucas, Morghan C; Timpson, Paul

    2016-01-01

    Intravital imaging is providing new insights into the dynamics of tumor progression in native tissues and has started to reveal the layers of complexity found in cancer. Recent advances in intravital imaging have allowed us to look deeper into cancer behavior and to dissect the interactions between tumor cells and the ancillary host niche that promote cancer development. In this review, we provide an insight into the latest advances in cancer biology achieved by intravital imaging, focusing on recently discovered mechanisms by which tumor cells manipulate normal tissue to facilitate disease progression. PMID:27239290

  10. Opportunities for ice storage to provide ancillary services to power grids incorporating wind turbine generation

    NASA Astrophysics Data System (ADS)

    Finley, Christopher

    Power generation using wind turbines increases the electrical system balancing, regulation and ramp rate requirements due to the minute to minute variability in wind speed and the difficulty in accurately forecasting wind speeds. The addition of thermal energy storage, such as ice storage, to a building's space cooling equipment increases the operational flexibility of the equipment by allowing the owner to choose when the chiller is run. The ability of the building owner to increase the power demand from the chiller (e.g. make ice) or to decrease the power demand (e.g. melt ice) to provide electrical system ancillary services was evaluated.

  11. Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression

    PubMed Central

    Lucas, Morghan C.; Timpson, Paul

    2016-01-01

    Intravital imaging is providing new insights into the dynamics of tumor progression in native tissues and has started to reveal the layers of complexity found in cancer. Recent advances in intravital imaging have allowed us to look deeper into cancer behavior and to dissect the interactions between tumor cells and the ancillary host niche that promote cancer development. In this review, we provide an insight into the latest advances in cancer biology achieved by intravital imaging, focusing on recently discovered mechanisms by which tumor cells manipulate normal tissue to facilitate disease progression. PMID:27239290

  12. Estimating the distribution of snow depth via artificial neural networks combined with MODIS snow cover area and ancillary topographic data

    NASA Astrophysics Data System (ADS)

    Hou, Jinliang; Huang, Chunlin

    2016-04-01

    Accurately estimate the distribution of snow depth (SD) is particularly difficult in mountainous environments given the complex topography, strong seasonal transition, and scarce observations. Passive microwave snow depth retrievals are too coarse to resolve small-scale terrain-induced variability; Optical sensors have the ability to determine the snow coverage extent at higher spatial resolution but not SD. By taking advantage of long time moderate-resolution optical sensors (MODIS) fractional snow cover (FSC) data series, the cubic spline interpolation algorithm is used to fill in data gaps caused by clouds in MODIS FSC Products. An innovative method based on multilayer feedforward artificial neural network (ANN) is presented to generate SD at a 500 m spatial resolution. This is trained with back propagation to learn the relationship between SD and FSC, Latitude and longitude, and ancillary topographic (e.g. elevation, slope, aspect) data. In this study, daily snow depth observations at 42 meteorological stationsare chosen to examine the proposed method during 2004 to 2005 snow seasons (from 1 November 2004 to 31 March 2005, 151 days) in northern Xinjiang Province, China. Among them, FSC, Latitude and longitude, and ancillary topographic data extracted from 35 sites are used as input information, and corresponding ground-based SD observations are used as desired output of ANN, thus a total of 151*35 samples are included in the ANN training set; Corresponding data from other 7 sites are used as independent test sample set (151*7 samples) to test the generalization ability of the ANN. Preliminary experimental results are very encouraging compared with the traditional multiple regression method. The performance evaluation results shows that the ANN derived SD have much higher coefficient of determination (R2) and lower root-mean-square error (RMSE), with R2 of 0.89 and 0.88, RMSE of 0.07 and 0.08, the mean absolute error of 2.3 and 2.3 cm for training and test

  13. Influence of Ancillary Ligands and Isomerism on the Luminescence of Bis-cyclometalated Platinum(IV) Complexes.

    PubMed

    Juliá, Fabio; García-Legaz, María-Dulce; Bautista, Delia; González-Herrero, Pablo

    2016-08-01

    The synthesis, characterization, and photophysical properties of a wide variety of bis-cyclometalated Pt(IV) complexes featuring a C2-symmetrical or unsymmetrical {Pt(ppy)2} unit (sym or unsym complexes, respectively; ppy = C-deprotonated 2-phenylpyridine) and different ancillary ligands are reported. Complexes sym-[Pt(ppy)2X2] (X = OTf(-), OAc(-)) were obtained by chloride abstraction from sym-[Pt(ppy)2Cl2] using the corresponding AgX salts, and the triflate derivative was employed to obtain homologous complexes with X = F(-), Br(-), I(-), trifluoroacetate (TFA(-)). Complexes unsym-[Pt(ppy)2(Me)X] (X = OTf(-), F(-)) were prepared by reacting unsym-[Pt(ppy)2(Me)Cl] with AgOTf or AgF, respectively, and the triflate derivative was employed as precursor for the synthesis of the homologues with X = Br(-), I(-), or TFA(-) through its reaction with the appropriate anionic ligands. The previously reported complexes unsym-[Pt(ppy)2X2] (X = Cl(-), Br(-), OAc(-), TFA(-)) are included in the photophysical study to assess the influence of the arrangement of the cyclometalated ligands. Density functional theory (DFT) and time-dependent DFT calculations on selected derivatives were performed for a better interpretation of the observed excited-state properties. Complexes sym-[Pt(ppy)2X2] (except X = I(-)) exhibit phosphorescent emissions in fluid solutions at 298 K arising from essentially (3)LC(ppy) excited states, which are very similar in shape and energy. However, their efficiencies are heavily dependent on the nature of the ancillary ligands, which affect the energy of deactivating ligand-to-ligand charge transfer (LLCT) or ligand-to-metal charge transfer (LMCT) states. The fluoride derivative sym-[Pt(ppy)2F2] shows the highest quantum yield of this series (Φ = 0.398), mainly because the relatively high metal-to-ligand charge transfer admixture in its emitting state leads to a high radiative rate constant. Complexes unsym-[Pt(ppy)2X2] emit from (3)LC(ppy) states in frozen

  14. Complementation for an essential ancillary nonstructural protein function across parvovirus genera

    PubMed Central

    Mihaylov, Ivailo S.; Cotmore, Susan F.; Tattersall, Peter

    2014-01-01

    Parvoviruses encode a small number of ancillary proteins that differ substantially between genera. Within the genus Protoparvovirus, minute virus of mice (MVM) encodes three isoforms of its ancillary protein NS2, while human bocavirus 1 (HBoV1), in the genus Bocaparvovirus, encodes an NP1 protein that is unrelated in primary sequence to MVM NS2. To search for functional overlap between NS2 and NP1, we generated murine A9 cell populations that inducibly express HBoV1 NP1. These were used to test whether NP1 expression could complement specific defects resulting from depletion of MVM NS2 isoforms. NP1 induction had little impact on cell viability or cell cycle progression in uninfected cells, and was unable to complement late defects in MVM virion production associated with low NS2 levels. However, NP1 did relocate to MVM replication centers, and supports both the normal expansion of these foci and overcomes the early paralysis of DNA replication in NS2-null infections. PMID:25194919

  15. Open Automated Demand Response Communications in Demand Response for Wholesale Ancillary Services

    SciTech Connect

    Kiliccote, Sila; Piette, Mary Ann; Ghatikar, Girish; Koch, Ed; Hennage, Dan; Hernandez, John; Chiu, Albert; Sezgen, Osman; Goodin, John

    2009-11-06

    The Pacific Gas and Electric Company (PG&E) is conducting a pilot program to investigate the technical feasibility of bidding certain demand response (DR) resources into the California Independent System Operator's (CAISO) day-ahead market for ancillary services nonspinning reserve. Three facilities, a retail store, a local government office building, and a bakery, are recruited into the pilot program. For each facility, hourly demand, and load curtailment potential are forecasted two days ahead and submitted to the CAISO the day before the operation as an available resource. These DR resources are optimized against all other generation resources in the CAISO ancillary service. Each facility is equipped with four-second real time telemetry equipment to ensure resource accountability and visibility to CAISO operators. When CAISO requests DR resources, PG&E's OpenADR (Open Automated DR) communications infrastructure is utilized to deliver DR signals to the facilities energy management and control systems (EMCS). The pre-programmed DR strategies are triggered without a human in the loop. This paper describes the automated system architecture and the flow of information to trigger and monitor the performance of the DR events. We outline the DR strategies at each of the participating facilities. At one site a real time electric measurement feedback loop is implemented to assure the delivery of CAISO dispatched demand reductions. Finally, we present results from each of the facilities and discuss findings.

  16. Organizational boundaries of medical practice: the case of physician ownership of ancillary services.

    PubMed

    Schneider, John E; Ohsfeldt, Robert L; Scheibling, Cara M; Jeffers, Sarah A

    2012-01-01

    Physician ownership of in-office ancillary services (IOASs) has come under increasing scrutiny. Advocates of argue that IOASs allow physicians to supervise the quality and coordination of care. Critics have argued that IOASs create financial incentives for physicians to increase ancillary service volume. In this paper we develop a conceptual framework to evaluate the tradeoffs associated with physician ownership of IOASs. There is some evidence supporting the existence of scope and transaction economies in IOASs. Improvement in flow and continuity of care are likely to generate scope economies and improvements in quality monitoring and reductions in consumer transaction costs are likely to generate transaction economies. Other factors include the capture of upstream and downstream profits, but these incentives are likely to be small compared to scope and transaction economies. Policy debates on the merits of IOASs should include an explicit assessment of these tradeoffs.This research was supported in part by funding from the American Association of Orthopaedic Surgeons (AAOS). PMID:22828324

  17. Access to Emissions Distributions and Related Ancillary Data through the ECCAD database

    NASA Astrophysics Data System (ADS)

    Darras, Sabine; Enriquez, Edgar; Granier, Claire; Liousse, Catherine; Boulanger, Damien; Fontaine, Alain

    2016-04-01

    The ECCAD database (Emissions of atmospheric Compounds and Compilation of Ancillary Data) provides a user-friendly access to global and regional surface emissions for a large set of chemical compounds and ancillary data (land use, active fires, burned areas, population,etc). The emissions inventories are time series gridded data at spatial resolution from 1x1 to 0.1x0.1 degrees. ECCAD is the emissions database of the GEIA (Global Emissions InitiAtive) project and a sub-project of the French Atmospheric Data Center AERIS (http://www.aeris-data.fr). ECCAD has currently more than 2200 users originating from more than 80 countries. The project benefits from this large international community of users to expand the number of emission datasets made available. ECCAD provides detailed metadata for each of the datasets and various tools for data visualization, for computing global and regional totals and for interactive spatial and temporal analysis. The data can be downloaded as interoperable NetCDF CF-compliant files, i.e. the data are compatible with many other client interfaces. The presentation will provide information on the datasets available within ECCAD, as well as examples of the analysis work that can be done online through the website: http://eccad.aeris-data.fr.

  18. Ancillary therapy of intranasal T-LysYal® for patients with allergic, non-allergic, and mixed rhinitis.

    PubMed

    Gelardi, M; Taliente, S; Fiorella, M L; Quaranta, N; Ciancio, G; Russo, C; Mola, P; Ciofalo, A; Zambetti, G; Caruso Armone, A; Cantone, E; Ciprandi, G

    2016-01-01

    Allergic rhinitis (AR) is caused by an IgE-mediated inflammatory reaction. Non-allergic rhinitis (NAR) is characterized by a non-IgE-mediated pathogenesis. Frequently, patients have the two disorders associated: such as mixed rhinitis (MR). Hyaluronic acid (HA) is a fundamental component of the human connective tissue. HA may exert anti-inflammatory and immune-modulating activities. Recently, an intranasal HA formulation was proposed: a supramolecular system containing lysine hyaluronate, thymine and sodium chloride (T-LysYal®). This randomized study investigated whether intranasal T-LysYal® (rinoLysYal®, Farmigea, Italy) was able to reduce symptom severity, endoscopic features, and nasal cytology in 89 patients (48 males and 41 females, mean age 36.3±7.1 years) with AR, NAR, and MR. Patients were treated with intranasal T-LysYal® or isotonic saline solution as adjunctive therapy to nasal corticosteroid and oral antihistamine for 4 weeks. Patients were visited at baseline, after treatment and after 4-week follow-up. Intranasal T-LysYal® treatment significantly reduced the quote of patients with symptoms, endoscopic features, and inflammatory cells. In conclusion, the present study demonstrates that intranasal T-LysYal® is able, as ancillary therapy, to significantly improve patients with AR, NAR, and MR, and its effect is long lasting. PMID:27049100

  19. Secure provision of reactive power ancillary services in competitive electricity markets

    NASA Astrophysics Data System (ADS)

    El-Samahy, Ismael

    decoupled and assumed to be fixed during the reactive power dispatch procedures; however, the effect of reactive power on real power is considered in the model by calculating the required reduction in real power output of a generator due to an increase in its reactive power supply. In this case, real power generation is allowed to be rescheduled, within given limits, from the already dispatched levels obtained from the energy market clearing process. The proposed dispatch model achieves the main objective of an ISO in a competitive electricity market, which is to provide the required reactive power support from generators at least cost while ensuring a secure operation of the power system. The proposed reactive power procurement and dispatch models capture both the technical and economic aspects of power system operation in competitive electricity markets; however, from an optimization point of view, these models represent non-convex mixed integer non-linear programming (MINLP) problems due to the presence of binary variables associated with the different regions of reactive power operation in a synchronous generator. Such MINLP optimization problems are difficult to solve, especially for an actual power system. A novel Generator Reactive Power Classification (GRPC) algorithm is proposed in this thesis to address this issue, with the advantage of iteratively solving the optimization models as a series of non-linear programming (NLP) sub-problems. The proposed reactive power procurement and dispatch models are implemented and tested on the CIGRE 32-bus system, with several case studies that represent different practical operating scenarios. The developed models are also compared with other approaches for reactive power provision, and the results demonstrate the robustness and effectiveness of the proposed model. The results clearly reveal the main features of the proposed models for optimal provision of reactive power ancillary service, in order to suit the requirements of

  20. Planck intermediate results. XXIII. Galactic plane emission components derived from Planck with ancillary data

    NASA Astrophysics Data System (ADS)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Alves, M. I. R.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Battaner, E.; Benabed, K.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bobin, J.; Bonaldi, A.; Bond, J. R.; Bouchet, F. R.; Boulanger, F.; Burigana, C.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chiang, H. C.; Christensen, P. R.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Couchot, F.; Crill, B. P.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Donzelli, S.; Doré, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Galeotta, S.; Ganga, K.; Génova-Santos, R. T.; Ghosh, T.; Giard, M.; Giardino, G.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Harrison, D. L.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lawrence, C. R.; Leonardi, R.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maino, D.; Mandolesi, N.; Martin, P. G.; Martínez-González, E.; Masi, S.; Massardi, M.; Matarrese, S.; Mazzotta, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Pasian, F.; Pearson, T. J.; Peel, M.; Perdereau, O.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Pratt, G. W.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reich, W.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Savini, G.; Scott, D.; Spencer, L. D.; Stolyarov, V.; Strong, A. W.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Terenzi, L.; Tibbs, C. T.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Varis, J.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Yvon, D.; Zacchei, A.; Zonca, A.

    2015-08-01

    Planck data when combined with ancillary data provide a unique opportunity to separate the diffuse emission components of the inner Galaxy. The purpose of the paper is to elucidate the morphology of the various emission components in the strong star-formation region lying inside the solar radius and to clarify the relationship between the various components. The region of the Galactic plane covered is l = 300° → 0° → 60° wherestar-formation is highest and the emission is strong enough to make meaningful component separation. The latitude widths in this longitude range lie between 1° and 2°, which correspond to FWHM z-widths of 100-200 pc at a typical distance of 6 kpc. The four emission components studied here are synchrotron, free-free, anomalous microwave emission (AME), and thermal (vibrational) dust emission. These components are identified by constructing spectral energy distributions (SEDs) at positions along the Galactic plane using the wide frequency coverage of Planck (28.4-857 GHz) in combination with low-frequency radio data at 0.408-2.3 GHz plus WMAP data at 23-94 GHz, along with far-infrared (FIR) data from COBE-DIRBE and IRAS. The free-free component is determined from radio recombination line (RRL) data. AME is found to be comparable in brightness to the free-free emission on the Galactic plane in the frequency range 20-40 GHz with a width in latitude similar to that of the thermal dust; it comprises 45 ± 1% of the total 28.4 GHz emission in the longitude range l = 300° → 0° → 60°. The free-free component is the narrowest, reflecting the fact that it is produced by current star-formation as traced by the narrow distribution of OB stars. It is the dominant emission on the plane between 60 and 100 GHz. RRLs from this ionized gas are used to assess its distance, leading to a free-free z-width of FWHM ≈ 100 pc. The narrow synchrotron component has a low-frequency brightness spectral index βsynch ≈ -2.7 that is similar to the broad

  1. Active mechanistic target of rapamycin plays an ancillary rather than essential role in zebrafish CNS axon regeneration

    PubMed Central

    Diekmann, Heike; Kalbhen, Pascal; Fischer, Dietmar

    2015-01-01

    The developmental decrease of the intrinsic regenerative ability of the mammalian central nervous system (CNS) is associated with reduced activity of mechanistic target of rapamycin (mTOR) in mature neurons such as retinal ganglion cells (RGCs). While mTOR activity is further decreased upon axonal injury, maintenance of its pre-injury level, for instance by genetic deletion of the phosphatase and tensin homolog (PTEN), markedly promotes axon regeneration in mammals. The current study now addressed the question whether active mTOR might generally play a central role in axon regeneration by analyzing its requirement in regeneration-competent zebrafish. Remarkably, regulation of mTOR activity after optic nerve injury in zebrafish is fundamentally different compared to mammals. Hardly any activity was detected in naïve RGCs, whereas it was markedly increased upon axotomy in vivo as well as in dissociated cell cultures. After a short burst, mTOR activity was quickly attenuated, which is contrary to the requirements for axon regeneration in mammals. Surprisingly, mTOR activity was not essential for axonal growth per se, but correlated with cytokine- and PTEN inhibitor-induced neurite extension in vitro. Moreover, inhibition of mTOR using rapamycin significantly reduced axon regeneration in vivo and compromised functional recovery after optic nerve injury. Therefore, axotomy-induced mTOR activity is involved in CNS axon regeneration in zebrafish similar to mammals, although it plays an ancillary rather than essential role in this regeneration-competent species. PMID:26217179

  2. Utilization of Ancillary Data Sets for Conceptual SMAP Mission Algorithm Development and Product Generation

    NASA Technical Reports Server (NTRS)

    O'Neill, P.; Podest, E.

    2011-01-01

    The planned Soil Moisture Active Passive (SMAP) mission is one of the first Earth observation satellites being developed by NASA in response to the National Research Council's Decadal Survey, Earth Science and Applications from Space: National Imperatives for the Next Decade and Beyond [1]. Scheduled to launch late in 2014, the proposed SMAP mission would provide high resolution and frequent revisit global mapping of soil moisture and freeze/thaw state, utilizing enhanced Radio Frequency Interference (RFI) mitigation approaches to collect new measurements of the hydrological condition of the Earth's surface. The SMAP instrument design incorporates an L-band radar (3 km) and an L band radiometer (40 km) sharing a single 6-meter rotating mesh antenna to provide measurements of soil moisture and landscape freeze/thaw state [2]. These observations would (1) improve our understanding of linkages between the Earth's water, energy, and carbon cycles, (2) benefit many application areas including numerical weather and climate prediction, flood and drought monitoring, agricultural productivity, human health, and national security, (3) help to address priority questions on climate change, and (4) potentially provide continuity with brightness temperature and soil moisture measurements from ESA's SMOS (Soil Moisture Ocean Salinity) and NASA's Aquarius missions. In the planned SMAP mission prelaunch time frame, baseline algorithms are being developed for generating (1) soil moisture products both from radiometer measurements on a 36 km grid and from combined radar/radiometer measurements on a 9 km grid, and (2) freeze/thaw products from radar measurements on a 3 km grid. These retrieval algorithms need a variety of global ancillary data, both static and dynamic, to run the retrieval models, constrain the retrievals, and provide flags for indicating retrieval quality. The choice of which ancillary dataset to use for a particular SMAP product would be based on a number of factors

  3. DR Resources for Energy and Ancillary Services in the West (Presentation)

    SciTech Connect

    Hummon, M.; Kiliccote, S.

    2014-04-01

    Demand response (DR) resources present a potentially important source of grid flexibility however, DR in grid models is limited by data availability and modeling complexity. This presentation focuses on the co-optimization of DR resources to provide energy and ancillary services in a production cost model of the Colorado "test system". We assume each DR resource can provide energy services by either shedding load or shifting its use between different times, as well as operating reserves: frequency regulation, contingency reserve, and flexibility (or ramping) reserve. There are significant variations in the availabilities of different types of DR resources, which affect both the operational savings as well as the revenue for each DR resource. The results presented include the system-wide avoided fuel and generator start-up costs as well as the composite revenue for each DR resource by energy and operating reserves.

  4. Critical Joints in Large Composite Primary Aircraft Structures. Volume 3: Ancillary Test Results

    NASA Technical Reports Server (NTRS)

    Bunin, Bruce L.; Sagui, R. L.

    1985-01-01

    A program was conducted to develop the technology for critical structural joints for composite wing structure that meets all the design requirements of a 1990 commercial transport aircraft. The results of a comprehensive ancillary test program are summarized, consisting of single-bolt composite joint specimens tested in a variety of configurations. These tests were conducted to characterize the strength and load deflection properties that are required for multirow joint analysis. The composite material was Toray 300 fiber and Ciba-Geigy 914 resin, in the form of 0.005 and 0.01 inch thick unidirectional tape. Tests were conducted in single and double shear for loaded and unloaded hole configurations under both tensile and compressive loading. Two different layup patterns were examined. All tests were conducted at room temperature. In addition, the results of NASA Standard Toughness Test (NASA RP 1092) are reported, which were conducted for several material systems.

  5. Engaging with research ethics in central Francophone Africa: reflections on a workshop about ancillary care

    PubMed Central

    2012-01-01

    Research ethics is predominantly taught and practiced in Anglophone countries, particularly those in North America and Western Europe. Initiatives to build research ethics capacity in developing countries must attempt to avoid imposing foreign frameworks and engage with ethical issues in research that are locally relevant. This article describes the process and outcomes of a capacity-building workshop that took place in Kinshasa, Democratic Republic of Congo in the summer of 2011. Although the workshop focused on a specific ethical theme – the responsibilities of researchers to provide health-related care to their research participants – we argue that the structure of the workshop offers a useful method for engaging with research ethics in general, and the theme of ancillary care encourages a broad perspective on research ethics that is highly pertinent in low-income countries. The workshop follows an interactive, locally driven model that could be fruitfully replicated in similar settings. PMID:22866822

  6. Territorial user rights for fisheries as ancillary instruments for marine coastal conservation in Chile.

    PubMed

    Gelcich, Stefan; Fernández, Miriam; Godoy, Natalio; Canepa, Antonio; Prado, Luis; Castilla, Juan Carlos

    2012-12-01

    Territorial user rights for fisheries have been advocated as a way to achieve sustainable resource management. However, few researchers have empirically assessed their potential as ancillary marine conservation instruments by comparing them to no-take marine protected areas. In kelp (Lessonia trabeculata) forests of central Chile, we compared species richness, density, and biomass of macroinvertebrates and reef fishes among territorial-user-right areas with low-level and high-level enforcement, no-take marine protected areas, and open-access areas in 42 100-m subtidal transects. We also assessed structural complexity of the kelp forest and substratum composition. Multivariate randomized permutation tests indicated macroinvertebrate and reef fish communities associated with the different access regimes differed significantly. Substratum composition and structural complexity of kelp forest did not differ among access regimes. Univariate analyses showed species richness, biomass, and density of macroinvertebrates and reef fishes were greater in highly enforced territorial-user-right areas and no-take marine protected areas than in open-access areas. Densities of macroinvertebrates and reef fishes of economic importance were not significantly different between highly enforced territorial-user-right and no-take marine protected areas. Densities of economically important macroinvertebrates in areas with low-level enforcement were significantly lower than those in areas with high-level enforcement and no-take marine protected areas but were significantly higher than in areas with open access. Territorial-user-right areas could be important ancillary conservation instruments if they are well enforced. PMID:22971114

  7. 47 CFR 25.254 - Special requirements for ancillary terrestrial components operating in the 1610-1626.5 MHz/2483.5...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....C. 552(a) and 1 CFR part 51. Copies of this standard can be inspected at the Federal Communications... MHz/2483.5-2500 MHz bands. (a) An applicant for an ancillary terrestrial component in these bands must... resolution bandwidth of one kilohertz or equivalent. (b) An applicant for an ancillary terrestrial...

  8. When No Bilingual Examiner Is Available: Exploring the Use of Ancillary Examiners as a Viable Testing Solution

    ERIC Educational Resources Information Center

    Noland, Ramona M.

    2009-01-01

    Reliable and valid assessment of individuals who are English language learners (ELL) has presented a dilemma to psychologists, and school psychologists in particular, as it is complicated by the small number of professionals qualified to serve as bilingual examiners. Some psychologists use ancillary examiners during testing when no bilingual…

  9. Improving Space-borne Radiometer Soil Moisture Retrievals with Alternative Aggregation Rules for Ancillary Parameters in Highly Heterogeneous Vegetated Areas

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Retrieving soil moisture from space-borne microwave radiometer observations often requires ancillary parameters such as surface vegetation opacity or vegetation water content. The conventional approach for deriving representative footprint-scale values of these parameters is to simply average the co...

  10. 75 FR 63167 - San Diego Gas and Electric Company v. Sellers of Energy and Ancillary Services Into Markets...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... Energy Regulatory Commission San Diego Gas and Electric Company v. Sellers of Energy and Ancillary... Power Exchange; Investigation of Practices of the California Independent System Operator and the California Power Exchange Corporation; Notice of Filing October 6, 2010. Take notice that on October 6,...

  11. 75 FR 22125 - Market-Based Rates for Wholesale Sales of Electric Energy, Capacity and Ancillary Services by...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-27

    ... Ancillary Services by Public Utilities; Notice of New Docket Prefix ``LA'' for Land Acquisition Reports and Guidelines for Filing Under Order No. 697-C April 20, 2010. Notice is hereby given that a new docket prefix... will now receive a new prefix ``LA'' as part of its designated docket number and will be...

  12. Development of a solid polymer electrolyte electrolysis cell module and ancillary components for a breadboard water electrolysis system

    NASA Technical Reports Server (NTRS)

    Porter, F. J., Jr.

    1972-01-01

    Solid polymer electrolyte technology in a water electrolysis system along with ancillary components to generate oxygen and hydrogen for a manned space station application are considered. Standard commercial components are utilized wherever possible. Presented are the results of investigations, surveys, tests, conclusions and recommendations for future development efforts.

  13. Monitoring basin-scale land cover changes in Kagera Basin of Lake Victoria using ancillary data and remote sensing

    NASA Astrophysics Data System (ADS)

    Wasige, John E.; Groen, Thomas A.; Smaling, Eric; Jetten, Victor

    2013-04-01

    The Kagera Basin is a high value ecosystem in the Lake Victoria watershed because of the hydrological and food services it provides. The basin has faced large scale human induced land use and land cover changes (LUCC), but quantitative data is to date lacking. A combination of ancillary data and satellite imagery were interpreted to construct LUCC dynamics for the last century. This study is an initial step towards assessing the impact of LUCC on sustainable agriculture and water quality in the watershed. The results show that large trends of LUCC have rapidly occurred over the last 100 years. The most dominant LUCC processes were gains in farmland areas (not detectable in 1901 to 60% in 2010) and a net reduction in dense forest (7% to 2.6%), woodlands (51% to 6.9%) and savannas (35% to 19.6%) between 1901 and 2010. Forest degradation rapidly occurred during 1974 and 1995 but the forest re-grew between 1995 and 2010 due to forest conservation efforts. Afforestation efforts have resulted in plantation forest increases between 1995 and 2010. The rates of LUCC observed are higher than those reported in Sub Saharan Africa (SSA) and other parts of the world. This is one of the few studies in SSA at a basin scale that combines multi-source spatio-temporal data on land cover to enable long-term quantification of land cover changes. In the discussion we address future research needs for the area based on the results of this study. These research needs include quantifying the impacts of land cover change on nutrient and sediment dynamics, soil organic carbon stocks, and changes in biodiversity.

  14. Preliminary Results of Ancillary Safety Analyses Supporting TREAT LEU Conversion Activities

    SciTech Connect

    Brunett, A. J.; Fei, T.; Strons, P. S.; Papadias, D. D.; Hoffman, E. A.; Kontogeorgakos, D. C.; Connaway, H. M.; Wright, A. E.

    2015-10-01

    The Transient Reactor Test Facility (TREAT), located at Idaho National Laboratory (INL), is a test facility designed to evaluate the performance of reactor fuels and materials under transient accident conditions. The facility, an air-cooled, graphite-moderated reactor designed to utilize fuel containing high-enriched uranium (HEU), has been in non-operational standby status since 1994. Currently, in support of the missions of the Department of Energy (DOE) National Nuclear Security Administration (NNSA) Material Management and Minimization (M3) Reactor Conversion Program, a new core design is being developed for TREAT that will utilize low-enriched uranium (LEU). The primary objective of this conversion effort is to design an LEU core that is capable of meeting the performance characteristics of the existing HEU core. Minimal, if any, changes are anticipated for the supporting systems (e.g. reactor trip system, filtration/cooling system, etc.); therefore, the LEU core must also be able to function with the existing supporting systems, and must also satisfy acceptable safety limits. In support of the LEU conversion effort, a range of ancillary safety analyses are required to evaluate the LEU core operation relative to that of the existing facility. These analyses cover neutronics, shielding, and thermal hydraulic topics that have been identified as having the potential to have reduced safety margins due to conversion to LEU fuel, or are required to support the required safety analyses documentation. The majority of these ancillary tasks have been identified in [1] and [2]. The purpose of this report is to document the ancillary safety analyses that have been performed at Argonne National Laboratory during the early stages of the LEU design effort, and to describe ongoing and anticipated analyses. For all analyses presented in this report, methodologies are utilized that are consistent with, or improved from, those used in analyses for the HEU Final Safety Analysis

  15. Ancillary therapies to enhance success of non-invasive modes of respiratory support - Approaches to delivery room use of surfactant and caffeine?

    PubMed

    Kribs, Angela; Hummler, Helmut

    2016-06-01

    During recent decades, non-invasive respiratory support has become popular for treating neonates with respiratory failure. Several prospective randomized controlled trials have been performed to compare use of continuous positive airway pressure (CPAP) as primary respiratory support in preterm infants with respiratory distress syndrome (RDS) to endotracheal intubation, mechanical ventilation and surfactant therapy. Systematic reviews of these studies suggest that routine CPAP at delivery is efficacious in decreasing bronchopulmonary dysplasia (BPD), death, or both. This led to the recommendation to consider CPAP to avoid endotracheal intubation. As surfactant therapy is known to reduce BPD and death, several ways to combine CPAP with surfactant have been described. With the increasing use of CPAP immediately after birth, the early use of caffeine to stimulate respiration has become a point of discussion. This review focuses on different modes of surfactant application during CPAP and on the early use of caffeine as ancillary therapies to enhance CPAP success. PMID:26936187

  16. Using ancillary information to improve hypocenter estimation: Bayesian single event location (BSEL)

    SciTech Connect

    Anderson, Dale N

    2008-01-01

    We have developed and tested an algorithm, Bayesian Single Event Location (BSEL), for estimating the location of a seismic event. The main driver for our research is the inadequate representation of ancillary information in the hypocenter estimation procedure. The added benefit is that we have also addressed instability issues often encountered with historical NLR solvers (e.g., non-convergence or seismically infeasible results). BSEL differs from established nonlinear regression techniques by using a Bayesian prior probability density function (prior PDF) to incorporate ancillary physical basis constraints about event location. P-wave arrival times from seismic events are used in the development. Depth, a focus of this paper, may be modeled with a prior PDF (potentially skewed) that captures physical basis bounds from surface wave observations. This PDF is constructed from a Rayleigh wave depth excitation eigenfunction that is based on the observed minimum period from a spectrogram analysis and estimated near-source elastic parameters. For example, if the surface wave is an Rg phase, it potentially provides a strong constraint for depth, which has important implications for remote monitoring of nuclear explosions. The proposed Bayesian algorithm is illustrated with events that demonstrate its congruity with established hypocenter estimation methods and its application potential. The BSEL method is applied to three events: (1) A shallow Mw 4 earthquake that occurred near Bardwell, KY on June 6, 2003, (2) the Mw 5.6 earthquake of July 26, 2005 that occurred near Dillon, MT, and (3) a deep Mw 5.7 earthquake that occurred off the coast of Japan on April 22, 1980. A strong Rg was observed from the Bardwell, KY earthquake that places very strong constraints on depth and origin time. No Rg was observed for the Dillon, MT earthquake, but we used the minimum observed period of a Rayleigh wave (7 seconds) to reduce the depth and origin time uncertainty. Because the Japan

  17. Automated ancillary cancer history classification for mesothelioma patients from free-text clinical reports

    PubMed Central

    Wilson, Richard A.; Chapman, Wendy W.; DeFries, Shawn J.; Becich, Michael J.; Chapman, Brian E.

    2010-01-01

    Background: Clinical records are often unstructured, free-text documents that create information extraction challenges and costs. Healthcare delivery and research organizations, such as the National Mesothelioma Virtual Bank, require the aggregation of both structured and unstructured data types. Natural language processing offers techniques for automatically extracting information from unstructured, free-text documents. Methods: Five hundred and eight history and physical reports from mesothelioma patients were split into development (208) and test sets (300). A reference standard was developed and each report was annotated by experts with regard to the patient’s personal history of ancillary cancer and family history of any cancer. The Hx application was developed to process reports, extract relevant features, perform reference resolution and classify them with regard to cancer history. Two methods, Dynamic-Window and ConText, for extracting information were evaluated. Hx’s classification responses using each of the two methods were measured against the reference standard. The average Cohen’s weighted kappa served as the human benchmark in evaluating the system. Results: Hx had a high overall accuracy, with each method, scoring 96.2%. F-measures using the Dynamic-Window and ConText methods were 91.8% and 91.6%, which were comparable to the human benchmark of 92.8%. For the personal history classification, Dynamic-Window scored highest with 89.2% and for the family history classification, ConText scored highest with 97.6%, in which both methods were comparable to the human benchmark of 88.3% and 97.2%, respectively. Conclusion: We evaluated an automated application’s performance in classifying a mesothelioma patient’s personal and family history of cancer from clinical reports. To do so, the Hx application must process reports, identify cancer concepts, distinguish the known mesothelioma from ancillary cancers, recognize negation, perform reference

  18. Lung VITAL: Rationale, design, and baseline characteristics of an ancillary study evaluating the effects of vitamin D and/or marine omega-3 fatty acid supplements on acute exacerbations of chronic respiratory disease, asthma control, pneumonia and lung function in adults.

    PubMed

    Gold, Diane R; Litonjua, Augusto A; Carey, Vincent J; Manson, JoAnn E; Buring, Julie E; Lee, I-Min; Gordon, David; Walter, Joseph; Friedenberg, Georgina; Hankinson, John L; Copeland, Trisha; Luttmann-Gibson, Heike

    2016-03-01

    Laboratory and observational research studies suggest that vitamin D and marine omega-3 fatty acids may reduce risk for pneumonia, acute exacerbations of respiratory diseases including chronic obstructive lung disease (COPD) or asthma, and decline of lung function, but prevention trials with adequate dosing, adequate power, and adequate time to follow-up are lacking. The ongoing Lung VITAL study is taking advantage of a large clinical trial-the VITamin D and OmegA-3 TriaL (VITAL)--to conduct the first major evaluation of the influences of vitamin D and marine omega-3 fatty acid supplementation on pneumonia risk, respiratory exacerbation episodes, asthma control and lung function in adults. VITAL is a 5-year U.S.-wide randomized, double-blind, placebo-controlled, 2 × 2 factorial trial of supplementation with vitamin D3 ([cholecalciferol], 2000 IU/day) and marine omega-3 FA (Omacor® fish oil, eicosapentaenoic acid [EPA]+docosahexaenoic acid [DHA], 1g/day) for primary prevention of CVD and cancer among men and women, at baseline aged ≥50 and ≥55, respectively, with 5107 African Americans. In a subset of 1973 participants from 11 urban U.S. centers, lung function is measured before and two years after randomization. Yearly follow-up questionnaires assess incident pneumonia in the entire randomized population, and exacerbations of respiratory disease, asthma control and dyspnea in a subpopulation of 4314 randomized participants enriched, as shown in presentation of baseline characteristics, for respiratory disease, respiratory symptoms, and history of cigarette smoking. Self-reported pneumonia hospitalization will be confirmed by medical record review, and exacerbations will be confirmed by Center for Medicare and Medicaid Services data review. PMID:26784651

  19. Electric industry restructuring, ancillary services, and the potential impact on wind

    SciTech Connect

    Kirby, B.; Hirst, E.; Parsons, B.; Porter, K.

    1997-12-31

    The new competitive electric power environment raises increased challenges for wind power. The DOE and EPRI wind programs have dealt extensively with the traditional vertically integrated utility planning and operating environment in which the host utility owns the generation (or purchases the power) and provides dispatch and transmission services. Under this traditional environment, 1794 MW of wind power, principally in California, have been successfully integrated into the U.S. electric power system. Another 4200 MW are installed elsewhere in the world. As issues have arisen, such as intermittency and voltage regulation, they have been successfully addressed with accepted power system procedures and practices. For an intermittent, non-dispatchable resource such as wind, new regulatory rules affecting power transmission services, raise questions about which ancillary services wind plants will be able to sell, which they will be required to purchase, and what the economic impacts will be on individual wind projects. This paper begins to look at issues of concern to wind in a restructured electric industry. The paper first briefly looks at the range of unbundled services and comments on their unique significance to wind. To illustrate the concerns that arise with restructuring, the paper then takes a more detailed look at a single service: regulation. Finally, the paper takes a brief look at technologies and strategies that could improve the competitive position of wind.

  20. Producing Alaska interim land cover maps from Landsat digital and ancillary data

    USGS Publications Warehouse

    Fitzpatrick-Lins, Katherine; Doughty, Eileen Flanagan; Shasby, Mark; Loveland, Thomas R.; Benjamin, Susan

    1987-01-01

    In 1985, the U.S. Geological Survey initiated a research program to produce 1:250,000-scale land cover maps of Alaska using digital Landsat multispectral scanner data and ancillary data and to evaluate the potential of establishing a statewide land cover mapping program using this approach. The geometrically corrected and resampled Landsat pixel data are registered to a Universal Transverse Mercator (UTM) projection, along with arc-second digital elevation model data used as an aid in the final computer classification. Areas summaries of the land cover classes are extracted by merging the Landsat digital classification files with the U.S. Bureau of Land Management's Public Land Survey digital file. Registration of the digital land cover data is verified and control points are identified so that a laser plotter can products screened film separate for printing the classification data at map scale directly from the digital file. The final land cover classification is retained both as a color map at 1:250,000 scale registered to the U.S. Geological Survey base map, with area summaries by township and range on the reverse, and as a digital file where it may be used as a category in a geographic information system.

  1. Fly DPP10 acts as a channel ancillary subunit and possesses peptidase activity

    PubMed Central

    Shiina, Yohei; Muto, Tomohiro; Zhang, Zhili; Baihaqie, Ahmad; Yoshizawa, Takamasa; Lee, Hye-in J.; Park, Eulsoon; Tsukiji, Shinya; Takimoto, Koichi

    2016-01-01

    Mammalian DPP6 (DPPX) and DPP10 (DPPY) belong to a family of dipeptidyl peptidases, but lack enzyme activity. Instead, these proteins form complexes with voltage-gated K+ channels in Kv4 family to control their gating and other properties. Here, we find that the fly DPP10 ortholog acts as an ancillary subunit of Kv4 channels and digests peptides. Similarly to mammalian DPP10, the fly ortholog tightly binds to rat Kv4.3 protein. The association causes negative shifts in voltage dependence of channel activation and steady state inactivation. It also results in faster inactivation and recovery from inactivation. In addition to its channel regulatory role, fly DPP10 exhibits significant dipeptidyl peptidase activity with Gly-Pro-MCA (glycyl-L-proline 4-methylcoumaryl-7-amide) as a substrate. Heterologously expressed Flag-tagged fly DPP10 and human DPP4 show similar Km values towards this substrate. However, fly DPP10 exhibits approximately a 6-times-lower relative kcat value normalized with anti-Flag immunoreactivity than human DPP4. These results demonstrate that fly DPP10 is a dual functional protein, controlling Kv4 channel gating and removing bioactive peptides. PMID:27198182

  2. Usefulness of ancillary methods for diagnosis, prognosis and targeted therapy in thyroid pathology.

    PubMed

    Bozec, A; Ilie, M; Lassalle, S; Hofman, V; Benaim, G; Long, E; Santini, J; Hofman, P

    2013-01-01

    The development of molecular analyses for thyroid pathologies is on going. These analyses provide new diagnostic tools with the aim of accurately distinguishing malignant and benign thyroid tumors. They are particularly useful as most of them can be done preoperatively on thyroid fine-needle aspiration biopsy samples. Furthermore, molecular biomarkers may play a promising role since they are able to predict the prognosis of patients with thyroid tumors. Moreover, identification of molecular markers as well as a better understanding of thyroid carcinogenesis will help develop innovative targeted therapies, particularly in patients with metastatic iodo-resistant thyroid carcinoma. To date, four types of somatic genetic alterations are known to hold potential interest for the diagnosis and/or prognosis of follicular cell-derived thyroid carcinomas: BRAF and RAS mutations, and RET/PTC and PAX8/PPARγ rearrangements. Other recent molecular biomarkers have been investigated in thyroid oncology, in particular different microRNA signatures. This review describes the different aspects of ancillary methods, including those bassed on molecular biology, that are of current interest for the diagnosis, prognosis and treatment of follicular cell-derived thyroid carcinomas. PMID:23298138

  3. Incorporating residential AC load control into ancillary service markets: Measurement and settlement

    SciTech Connect

    Bode, Josh L.; Sullivan, Michael J.; Berghman, Dries; Eto, Joseph H.

    2013-05-01

    Many pre-existing air conditioner load control programs can provide valuable operational flexibility but have not been incorporated into electricity ancillary service markets or grid operations. Multiple demonstrations have shown that residential air conditioner (AC) response can deliver resources quickly and can provide contingency reserves. A key policy hurdle to be overcome before AC load control can be fully incorporated into markets is how to balance the accuracy, cost, and complexity of methods available for the settlement of load curtailment. Overcoming this hurdle requires a means for assessing the accuracy of shorter-term AC load control demand reduction estimation approaches in an unbiased manner. This paper applies such a method to compare the accuracy of approaches varying in cost and complexity ? including regression analysis, load matching and control group approaches ? using feeder data, household data and AC end-use data. We recommend a practical approach for settlement, relying on an annually updated set of tables, with pre-calculated reduction estimates. These tables allow users to look up the demand reduction per device based on daily maximum temperature, geographic region and hour of day, simplifying settlement and providing a solution to the policy problem presented in this paper.

  4. Analysis of the Effects of a Flexible Ramping Ancillary Service Product on Power System Operations: Preprint

    SciTech Connect

    Krad, Ibrahim; Ibanez, Eduardo; Ela, Erik

    2015-10-19

    The recent increased interest in utilizing variable generation (VG) resources such as wind and solar in power systems has motivated investigations into new operating procedures. Although these resources provide desirable value to a system (e.g., no fuel costs or emissions), interconnecting them provides unique challenges. Their variable, non-controllable nature in particular requires significant attention, because it directly results in increased power system variability and uncertainty. One way to handle this is via new operating reserve schemes. Operating reserves provide upward and downward generation and ramping capacity to counteract uncertainty and variability prior to their realization. For instance, uncertainty and variability in real-time dispatch can be accounted for in the hour-ahead unit commitment. New operating reserve methodologies that specifically account for the increased variability and uncertainty caused by VG are currently being investigated and developed by academia and industry. This paper examines one method inspired by the new operating reserve product being proposed by the California Independent System Operator. The method is based on examining the potential ramping requirements at any given time and enforcing those requirements via a reserve demand curve in the market-clearing optimization as an additional ancillary service product.

  5. Fly DPP10 acts as a channel ancillary subunit and possesses peptidase activity.

    PubMed

    Shiina, Yohei; Muto, Tomohiro; Zhang, Zhili; Baihaqie, Ahmad; Yoshizawa, Takamasa; Lee, Hye-In J; Park, Eulsoon; Tsukiji, Shinya; Takimoto, Koichi

    2016-01-01

    Mammalian DPP6 (DPPX) and DPP10 (DPPY) belong to a family of dipeptidyl peptidases, but lack enzyme activity. Instead, these proteins form complexes with voltage-gated K(+) channels in Kv4 family to control their gating and other properties. Here, we find that the fly DPP10 ortholog acts as an ancillary subunit of Kv4 channels and digests peptides. Similarly to mammalian DPP10, the fly ortholog tightly binds to rat Kv4.3 protein. The association causes negative shifts in voltage dependence of channel activation and steady state inactivation. It also results in faster inactivation and recovery from inactivation. In addition to its channel regulatory role, fly DPP10 exhibits significant dipeptidyl peptidase activity with Gly-Pro-MCA (glycyl-L-proline 4-methylcoumaryl-7-amide) as a substrate. Heterologously expressed Flag-tagged fly DPP10 and human DPP4 show similar Km values towards this substrate. However, fly DPP10 exhibits approximately a 6-times-lower relative kcat value normalized with anti-Flag immunoreactivity than human DPP4. These results demonstrate that fly DPP10 is a dual functional protein, controlling Kv4 channel gating and removing bioactive peptides. PMID:27198182

  6. star Miner: A suit of classifiers for spatial, temporal, ancillary, and remote sensing data mining

    SciTech Connect

    Vatsavai, Raju; Shekhar, Shashi; Burk, Thomas E; Bhaduri, Budhendra L

    2008-01-01

    Thematic classification of multi-spectral remotely sensed imagery for large geographic regions requires complex algorithms and feature selection techniques. Traditional statistical classifiers rely exclusively on spectral characteristics, but thematic classes are often spectrally overlapping. The spectral response distributions of thematic classes are dependent on many factors including terrain, slope, aspect, soil type, and atmospheric conditions present during the image acquisition. With the availability of geo-spatial databases, it is possible to exploit the knowledge derived from these ancillary geo-spatial databases to improve the classification accuracies. However, it is not easy to incorporate this additional knowledge into traditional statistical classification methods. On the other hand, knowledge-based and neural network classifiers can readily incorporate these spatial databases, but these systems are often complex to train and their accuracy is only slightly better than statistical classifiers. In this paper we present a new suit of classifiers developed through NASA funding, which addresses many of these problems and provide a framework for mining multi-spectral and temporal remote sensing images guided by geo-spatial databases.

  7. Current perspectives on the use of ancillary materials for the manufacture of cellular therapies.

    PubMed

    Solomon, Jennifer; Csontos, Lynn; Clarke, Dominic; Bonyhadi, Mark; Zylberberg, Claudia; McNiece, Ian; Kurtzberg, Joanne; Bell, Rosemarie; Deans, Robert

    2016-01-01

    Continued growth in the cell therapy industry and commercialization of cell therapies that successfully advance through clinical trials has led to increased awareness around the need for specialized and complex materials utilized in their manufacture. Ancillary materials (AMs) are components or reagents used during the manufacture of cell therapy products but are not intended to be part of the final products. Commonly, there are limitations in the availability of clinical-grade reagents used as AMs. Furthermore, AMs may affect the efficacy of the cell product and subsequent safety of the cell therapy for the patient. As such, AMs must be carefully selected and appropriately qualified during the cell therapy development process. However, the ongoing evolution of cell therapy research, limited number of clinical trials and registered cell therapy products results in the current absence of specific regulations governing the composition, compliance, and qualification of AMs often leads to confusion by suppliers and users in this field. Here we provide an overview and interpretation of the existing global framework surrounding AM use and investigate some common misunderstandings within the industry, with the aim of facilitating the appropriate selection and qualification of AMs. The key message we wish to emphasize is that in order to most effectively mitigate risk around cell therapy development and patient safety, users must work with their suppliers and regulators to qualify each AM to assess source, purity, identity, safety, and suitability in a given application. PMID:26596503

  8. Workshop on environmental assessment. [Regulation of applications of nuclear energy and related ancillary systems

    SciTech Connect

    Watson, E.C.

    1982-07-01

    Objectives of the workshop were: to review and evaluate the state-of-the-art of environmental impact assessments as applied to the regulation of applications of nuclear energy and related ancillary systems; to identify areas where existing technology allows establishing acceptable methods or standard practices that will meet the requirements of the NRC regulations, standards and guides for both normal operations and off-standard conditions including accident considerations; to illuminate topics where existing models or analytical methods are deficient because of unverified assumptions, a paucity of empirical data, conflicting results reported in the literature or a need for observation of operation systems; to compile, analyze and synthesize a prioritized set of research needs to advance the state-of-the-art to the level which will meet all of the requirements of the Commission's regulations, standards and guides; and to develop bases for maintaining the core of regulatory guidance at the optimum level balancing technical capabilities with practical considerations of cost and value to the regulatory process. The discussion held in small group sessions on aquatic, atmospheric, and terrestrial pathways are presented. The following research needs were identified as common to all three groups: validation of models; characterization of source terms; development of screening techniques; basis for de minimis levels of contamination; and updating of objectives for environmental monitoring programs.

  9. Established and emerging ancillary techniques in management of microbial keratitis: a review.

    PubMed

    Robaei, Dana; Carnt, Nicole; Watson, Stephanie

    2016-09-01

    Microbial keratitis is a sight-threatening condition and an ocular emergency, because of the potential for rapid progression. Intensive topical antimicrobials are the mainstay and the gold standard of treatment for microbial keratitis. However, despite appropriate diagnosis and therapy, treatment failure is still common, and can result in significant morbidity due to corneal perforation and/or scarring. For this reason, clinicians continue to seek novel treatment techniques in order to expand the armamentarium of tools available to manage microbial keratitis, and in doing so improve clinical outcomes. In this review, we examine the evidence for some established, as well as a few emerging ancillary techniques used to manage microbial keratitis. These include topical corticosteroids, corneal collagen cross-linking, intrastromal antimicrobials, amniotic membrane transplantation and miscellaneous other techniques. Of these, collagen cross-linking shows some promise for selected cases of infectious keratitis, although more research in the area is required before it is accepted as mainstream treatment for this potentially blinding condition. PMID:26888977

  10. Cost-Causation-Based Tariffs for Wind Ancillary Service Impacts: Preprint

    SciTech Connect

    Kirby, B.; Milligan, M.; Wan, Y.

    2006-06-01

    Conference paper discussing the integration cost of wind. Although specific tariffs for wind generation for ancillary services are uncommon, we anticipate that balancing authorities (control areas) and other entities will move toward such tariffs. Tariffs for regulation and imbalance services should be cost-based, recognize the relevant time scales that correspond with utility operational cycles, and properly allocate those costs to those entities that cause the balancing authority to incur the costs. In this paper, we present methods for separating wind's impact into regulation and load following (imbalance) time scales. We show that approximating these impacts with simpler methods can significantly distort cost causation and even cause confusion between the relevant time scales. We present results from NREL's wind data collection program to illustrate the dangers of linearly scaling wind resource data from small wind plants to approximate the wind resource data from large wind plants. Finally, we provide a framework for developing regulation and imbalance tariffs, we outline methods to begin examining contingency reserve requirements for wind plants, we provide guidance on the important characteristics to consider, and we provide hypothetical cases that the tariff can be tested against to determine whether the results are desired.