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Sample records for curium 246 target

  1. SEPARATION OF CURIUM AND AMERICIUM

    DOEpatents

    Fields, P.R.; Isaac, N.M.

    1962-02-20

    Curium and americium are contained in an anhydrous molten salt medium having a low melting point. Curium is preferentially extracted from the molten salt by a hot organic solvent containing preferably less than 10% alkyl phosphate. (AEC)

  2. Recovering Americium and Curium from Mark-42 Target Materials- New Processing Approaches to Enhance Separations and Integrate Waste Stream Disposition - 12228

    SciTech Connect

    Patton, Brad D.; Benker, Dennis; Collins, Emory D.; Mattus, Catherine H.; Robinson, Sharon M.; Wham, Robert M.

    2012-07-01

    Oak Ridge National Laboratory (ORNL) is investigating flowsheets to enhance processing efficiencies and to address waste streams associated with recovery of americium (Am) and curium (Cm) from Mark-42 (Mk-42) target materials stored at ORNL. The objective of this work was to identify the most effective flowsheet with which to process the 104 Mk-42 oxide capsules holding a total of 80 g of plutonium (Pu), 190 g of Cm, 480 g of Am, and 5 kg of lanthanide (Ln) oxides for the recovery and purification of the Am/Cm for future use as feedstock for heavy actinide production. Studies were also conducted to solidify the process flowsheet waste streams for disposal. ORNL is investigating flowsheets to enhance processing efficiencies and address waste streams associated with recovery of Am and Cm from Mk-42 target materials stored at ORNL. A series of small-scale runs are being performed to demonstrate an improved process to recover Am/Cm and to optimize the separations of Ln fission products from the Am/Cm constituents. The first of these runs has been completed using one of the Am/Cm/Ln oxide capsules stored at ORNL. The demonstration run showed promising results with a Ln DF of 40 for the Am/Cm product and an Am/Cm DF of 75 for the Ln product. In addition, the total losses of Am, Cm, and Ln to the waste solvents and raffinates were very low at <0.2%, 0.02%, and 0.04%, respectively. However, the Ln-actinide separation was less than desired. For future Reverse TALSPEAK demonstration runs, several parameters will be adjusted (flow rates, the ratio of scrub to strip stages, etc.) to improve the removal of Ln from the actinides. The next step will also include scale-up of the processing flowsheet to use more concentrated solutions (15 g/L Ln versus 5 g/L) and larger volumes and to recycle the HDEHP solvent. This should improve the overall processing efficiency and further reduce losses to waste streams. Studies have been performed with simulated wastes to develop solidification

  3. Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer Therapy

    PubMed Central

    Bykov, Vladimir J. N.; Zhang, Qiang; Zhang, Meiqiongzi; Ceder, Sophia; Abrahmsen, Lars; Wiman, Klas G.

    2016-01-01

    TP53 is the most frequently mutated gene in cancer. The p53 protein activates transcription of genes that promote cell cycle arrest or apoptosis, or regulate cell metabolism, and other processes. Missense mutations in TP53 abolish specific DNA binding of p53 and allow evasion of apoptosis and accelerated tumor progression. Mutant p53 often accumulates at high levels in tumor cells. Pharmacological reactivation of mutant p53 has emerged as a promising strategy for improved cancer therapy. Small molecules that restore wild type activity of mutant p53 have been identified using various approaches. One of these molecules, APR-246, is a prodrug that is converted to the Michael acceptor methylene quinuclidinone (MQ) that binds covalently to cysteines in p53, leading to refolding and restoration of wild type p53 function. MQ also targets the cellular redox balance by inhibiting thioredoxin reductase (TrxR1) and depleting glutathione. This dual mechanism of action may account for the striking synergy between APR-246 and platinum compounds. APR-246 is the only mutant p53-targeting compound in clinical development. A phase I/IIa clinical trial in hematological malignancies and prostate cancer showed good safety profile and clinical effects in some patients. APR-246 is currently tested in a phase Ib/II trial in patients with high-grade serous ovarian cancer. PMID:26870698

  4. (Structural investigation of curium bismuthide)

    SciTech Connect

    Haire, R.G.

    1990-10-12

    The primary objective of the collaborative studies with EITU was to study curium bismuthide using energy dispersive X-ray diffraction to monitor its structure as a function of pressure. This objective was accomplished and the material was investigated up to 0.48 megabars of pressure. These studies were a continuation of established and productive collaborations between ORNL and EITU. The study of this curium compound is significant in that it is the first 5f-element bismuthide to be studied under pressure. Bismuth has the highest Z and the largest radius of the pnictogen group of elements (important for Hill Plot assessments) and has the greatest potential to form f-p type bonding with actinides under pressure. From a preliminary assessment of our experimental data it has been determined that two structural transitions occurred in the curium bismuthide sample as a result of the applied pressure.

  5. Neutron irradiation of Am-241 effectively produces curium

    NASA Technical Reports Server (NTRS)

    Anderson, R. W.; Milstead, J.; Stewart, D. C.

    1967-01-01

    Computer study was made on the production of multicurie amounts of highly alpha-active curium 242 from americium 241 irradiation. The information available includes curium 242 yields, curium composition, irradiation data, and production techniques and safeguards.

  6. Frontiers of Chemistry for Americium and Curium

    DOE R&D Accomplishments Database

    Keller, O. L. Jr.

    1984-01-01

    The discoveries of americium and curium were made only after Seaborg had formulated his actinide concept in order to design the chemistry needed to separate them from irradiated /sup 239/Pu targets. Their discoveries thus furnished the first clear-cut evidence that the series exists and justified Seaborg`s bold assumption that even though Th and Pa appeared to presage a following 6d series, the pattern established by the periodic table after Cs and Ba would be repeated exactly after Fr and Ra. That is to say, a new 5f element rare earth series (the actinides) would follow Ac in the same way the 4f rare earth series (the lanthanides) follows La. The consequences of the resulting half-filled 5f/sup 7/ shell at Cm were originally presented by Seaborg as a test of his hypothesis. Recent research is outlined that substantiates Seaborg`s predictions in new and definitive ways.

  7. Frontiers of chemistry for americium and curium

    SciTech Connect

    Keller, O.L. Jr.

    1984-01-01

    The discoveries of americium and curium were made only after Seaborg had formulated his actinide concept in order to design the chemistry needed to separate them from irradiated /sup 239/Pu targets. Their discoveries thus furnished the first clear-cut evidence that the series exists and justified Seaborg's bold assumption that even though Th and Pa appeared to presage a following 6d series, the pattern established by the periodic table after Cs and Ba would be repeated exactly after Fr and Ra. That is to say, a new 5f element rare earth series (the actinides) would follow Ac in the same way the 4f rare earth series (the lanthanides) follows La. The consequences of the resulting half-filled 5f/sup 7/ shell at Cm were originally presented by Seaborg as a test of his hypothesis. Recent research is outlined that substantiates Seaborg's predictions in new and definitive ways. 15 references, 4 figures.

  8. The New Element Curium (Atomic Number 96)

    DOE R&D Accomplishments Database

    Seaborg, G. T.; James, R. A.; Ghiorso, A.

    1948-01-01

    Two isotopes of the element with atomic number 96 have been produced by the helium-ion bombardment of plutonium. The name curium, symbol Cm, is proposed for element 96. The chemical experiments indicate that the most stable oxidation state of curium is the III state.

  9. Electronic structure of neutral and singly ionized curium

    SciTech Connect

    Worden, E.F.; Conway, J.G.; Blaise, J.

    1985-02-01

    Extensive observations and analyses of the emission spectra of neutral and singly ionized curium, Cm I and Cm II, have resulted in the determination of 785 Cm I and 598 Cm II energy levels. These levels then combine to classify 9145 of the more than 14,250 lines of /sup 244/Cm observed between 240 and 2650 nm. Most of the levels have Lande g-values from Zeeman effect data and isotope shifts trom measurements of spectra from sources with various enrichments of /sup 244/Cm, /sup 245/Cm, /sup 246/Cm, and /sup 248/Cm. These data allowed many levels to be assigned to specific electronic configurations. The ground configurations of Cm I and Cm II are (Rn) 5f/sup 7/6d7s/sup 2/ and (Rn) 5f/sup 7/7s/sup 2/, respectively. The realtive energies of other electronic configurations of Cm are given and compared with analogous configurations in other actinides and in Gd its lanthanide analogue. 2 refs., 5 figs., 7 tabs.

  10. Preparation and X-ray diffraction studies of curium hydrides

    NASA Astrophysics Data System (ADS)

    Gibson, J. K.; Haire, R. G.

    1985-10-01

    Curium hydrides were prepared by reaction of curium-248 metal with hydrogen and characterized by X-ray powder diffraction. Several of the syntheses resulted in a hexagonal compound with average lattice parameters of a0 = 0.3769(8) nm and c0 = 0.6732(12) nm. These products are considered to be CmH 3-δ by analogy with the behavior of lanthanide-hydrogen and lighter actinide-hydrogen systems. Face-centered cubic products with an average lattice parameter of a0 = 0.5322(4) nm were obtained from other curium hydride preparations. This parameter is slightly smaller than that reported previously for cubic curium dihydride, CmH 2+ x (B. M. Bansal and D. Damien, Inorg. Nucl. Chem. Lett., 6, 603, 1970). The present results established a continuation of typical heavy trivalent lanthanide-like behavior of the transuranium actinide-hydrogen systems through curium.

  11. Interaction of divalent plutonium and curium

    SciTech Connect

    Mikheev, N.B.; Kazakevich, M.Z.; Rumer, I.A.

    1988-11-01

    It has been established that at plutonium concentrations ranging from 10/sup -5/ to 10/sup -4/ mole % the oxidation potentials of the Pu/sup 3 +//Pu/sup 2 +/ and Cm/sup 3 +//Cm/sup 2 +/ pairs increased by 0.15-0.2 V due to the dimerization of Pu/sup 2 +/ and the formation of mixed dimers of plutonium and curium. Promethium(2+) does not have a similar ability to form mixed dimers owing to the fact that Pm/sup 2 +/ does not have a free d electron. The oxidation potential of the Pm/sup 3 +//Pm/sup 2 +/ pair does not vary in the presence of massive quantities of plutonium

  12. PROCESS FOR SEPARATING AMERICIUM AND CURIUM FROM RARE EARTH ELEMENTS

    DOEpatents

    Baybarz, R.D.; Lloyd, M.H.

    1963-02-26

    This invention relates to methods of separating americium and curium values from rare earth values. In accordance with the invention americium, curium, and rare earth values are sorbed on an anion exchange resin. A major portion of the rare earth values are selectively stripped from the resin with a concentrated aqueous solution of lithium chloride, and americium, curium, and a minor portion of rare earth values are then stripped from the resin with a dilute aqueous solution of lithium chloride. The americium and curium values are further purified by increasing the concentration of lithium chloride in the solution to at least 8 molar and selectively extracting rare earth values from the resulting solution with a monoalkylphosphoric acid. (AEC)

  13. Americium/Curium Disposition Life Cycle Planning Study

    SciTech Connect

    Jackson, W.N.; Krupa, J.; Stutts, P.; Nester, S.; Raimesch, R.

    1998-04-30

    At the request of the Department of Energy Savannah River Office (DOE- SR), Westinghouse Savannah River Company (WSRC) evaluated concepts to complete disposition of Americium and Curium (Am/Cm) bearing materials currently located at the Savannah River Site (SRS).

  14. SRNL Development of Recovery Processes for Mark-18A Heavy Actinide Targets

    SciTech Connect

    Allender, Jeffrey S.; Bridges, Nicholas J.; Loftin, Bradley M.; Dunsmuir, Michael D.

    2015-07-14

    Savannah River National Laboratory (SRNL) and Oak Ridge National Laboratory (ORNL) are developing plans for the recovery of rare and unique isotopes contained within heavy-actinide target assemblies, specifically the Mark-18A. Mark-18A assemblies were irradiated in Savannah River Site (SRS) reactors in the 1970s under extremely high neutron-flux conditions and produced, virtually, the world's supply of plutonium-244, an isotope of key importance to high-precision actinide measurement and other scientific and nonproliferation uses; and curium highly enriched in heavy isotopes (e.g., curium-246 and curium-248). In 2015 and 2016, SRNL is pursuing tasks that would reduce program risk and budget requirements, including further characterization of unprocessed targets; engineering studies for the use of the SRNL Shielded Cells Facility (SCF) for recovery; and development of onsite and offsite shipping methods including a replacement for the heavy (70 ton) cask previously used for onsite transfer of irradiated items at SRS. A status update is provided for the characterization, including modeling using the Monte Carlo N-Particle Transport Code (MCNP); direct non-destructive assay measurements; and cask design.

  15. Spontaneous Partitioning of Californium from Curium: Curious Cases from the Crystallization of Curium Coordination Complexes

    SciTech Connect

    Cary, Samantha K.; Silver, Mark A.; Liu, Guokui; Wang, Jamie C.; Bogart, Justin A.; Stritzinger, Jared T.; Arico, Alexandra A.; Hanson, Kenneth; Schelter, Eric J.; Albrecht-Schmitt, Thomas E.

    2015-12-07

    The reaction of 248CmCl3 with excess 2,6-pyridinedicarboxylic acid (DPA) under mild solvothermal conditions results in crystallization of the tris-chelate complex Cm(HDPA)3·H2O. Approximately half of the curium remains in solution at the end of this process, and evaporation of the mother liquor results in crystallization of the bis-chelate complex [Cm(HDPA)- (H2DPA)(H2O)2Cl]Cl·2H2O. 248Cm is the daughter of the α decay of 252Cf and is extracted in high purity from this parent. However, trace amounts of 249,250,251Cf are still present in all samples of 248Cm. During the crystallization of Cm(HDPA)3·H2O and [Cm(HDPA)(H2DPA)(H2O)2Cl]Cl·2H2O, californium(III) spontaneously separates itself from the curium complexes and is found doped within crystals of DPA in the form of Cf(HDPA)3. These results add to the growing body of evidence that the chemistry of californium is fundamentally different from that of earlier actinides.

  16. Process for the recovery of curium-244 from nuclear waste

    SciTech Connect

    Posey, J.C.

    1980-10-01

    A process has been designed for the recovery of curium from purex waste. Curium and americium are separated from the lanthanides by a TALSPEAK extraction process using differential extraction. Equations were derived for the estimation of the economically optimum conditions for the extraction using laboratory batch extraction data. The preparation of feed for the extraction involves the removal of nitric acid from the Purex waste by vaporization under reduced pressure, the leaching of soluble nitrates from the resulting cake, and the oxalate precipitation of a pure lanthanide-actinide fraction. Final separation of the curium from americium is done by ion-exchange. The steps of the process, except ion-exchange, were tested on a laboratory scale and workable conditions were determined.

  17. Separation of transuranium elements from irradiated targets

    SciTech Connect

    Wham, R.M.; Benker, D.E.; Felker, L.K.; Chattin, F.R.

    1993-12-31

    Aluminum targets containing curium/americium oxide are irradiated to produce the transcurium actinides einsteinium, fermium, berkelium, and californium. Recovery of recycle curium/americium and the transcurium elements involves several chemical processing steps to selectively recover those elements and remove fission products. Chemical processing steps developed at the Radiochemical Engineering Development Center (REDC) include aluminum dejacketing, solvent extraction to remove bulk impurities, solvent extraction to remove plutonium, anion exchange to partition curium and transcurium elements from the rare earths, and a second anion exchange cycle to separate americium/curium from the transcurium elements.

  18. SIMULTANEOUS DETERMINATION OF AMERICIUM AND CURIUM IN SOIL

    EPA Science Inventory

    A method is presented for the routine determination of americium and curium in 10 g of soil. The soil is dissolved with a mixture of nitric acid and hydrofluoric acid. Insoluble sulfates and phosphates are metathesized with boiling sodium hydroxide solutions. Plutonium and iron a...

  19. Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells.

    PubMed

    Ali, Dina; Mohammad, Dara K; Mujahed, Huthayfa; Jonson-Videsäter, Kerstin; Nore, Beston; Paul, Christer; Lehmann, Sören

    2016-07-01

    The small molecule APR-246 (PRIMA-1(MET) ) is a novel drug that restores the activity of mutated and unfolded TP53 protein. However, the mechanisms of action and potential off-target effects are not fully understood. Gene expression profiling in TP53 mutant KMB3 acute myeloid leukaemia (AML) cells showed that genes which protected cells from oxidative stress to be the most up-regulated. APR-246 exposure also induced reactive oxygen species (ROS) formation and depleted glutathione in AML cells. The genes most up-regulated by APR-246, confirmed by quantitative real time polymerase chain reaction, were heme oxygenase-1 (HMOX1, also termed HO-1), SLC7A11 and RIT1. Up-regulation of HMOX1, a key regulator of cellular response to ROS, was independent of TP53 mutational status. NFE2L2 (also termed Nrf2), a master regulator of HMOX1 expression, showed transcriptional up-regulation and nuclear translocation by APR-246. Down-regulation of NFE2L2 by siRNA in AML cells significantly increased the antitumoural effects of APR-246. The PI3K inhibitor wortmannin and the mTOR inhibitor rapamycin inhibited APR-246-induced nuclear translocation of NFE2L2 and counteracted the protective cellular responses to APR-246, resulting in synergistic cell killing together with APR-246. In conclusion, ROS induction is important for antileukaemic activities of APR-246 and inhibiting the protective response of the Nrf-2/HMOX1 axis using PI3K inhibitors, enhances the antileukaemic effects. PMID:26991755

  20. Curium-244 alpha-sources for space research

    PubMed

    Radchenko; Andreichikov; Wanke; Gavrilo; Korchuganov; Rieder; Ryabinin; Economou

    2000-10-01

    Special alpha-proton-X-ray spectrometric complexes (APXS) have been developed in order to perform chemical analyses of the Mars atmosphere and rock surface compounds by alpha back-scattering, alpha-proton measurements, and X-ray fluorescence. The sources were prepared by high temperature condensation of metal curium vapour onto silicon substrates. They are silicon disks with curium-244 fixed on their surfaces as a silicide. The sources have overall dimensions as follows: disk diameter 8 mm; thickness 0.3 mm; and 6 mm diameter active spot. The source activities are 5 +/- 1 mCi and the alpha-line half-widths are equal to (1.7-2.5) and (2.9-4.5)% of full width at 10% of Maximum (Maximum is equal to 5.8 MeV). Thermovacuum (from 196 to 1000 degrees C), mechanical, and resource tests were performed and demonstrated that the sources maintained their characteristics. The applicability of the sources for the above-mentioned analytical purposes was confirmed during NASA Mars Pathfinder mission. PMID:11003526

  1. Sensitizing Curium Luminescence through an Antenna Protein to Investigate Biological Actinide Transport Mechanisms

    PubMed Central

    Sturzbecher-Hoehne, Manuel; Goujon, Christophe; Deblonde, Gauthier J.-P.; Mason, Anne B.; Abergel, Rebecca J.

    2013-01-01

    Worldwide stocks of actinides and lanthanide fission products produced through conventional nuclear spent fuel are increasing continuously, resulting in a growing risk of environmental and human exposure to these toxic radioactive metal ions. Understanding the bio-molecular pathways involved in mammalian uptake, transport and storage of these f-elements is crucial to the development of new decontamination strategies and could also be beneficial to the design of new containment and separation processes. To start unraveling these pathways, our approach takes advantage of the unique spectroscopic properties of trivalent curium. We clearly show that the human iron transporter transferrin acts as an antenna that sensitizes curium luminescence through intramolecular energy transfer. This behavior has been used to describe the coordination of curium within the two binding sites of the protein and to investigate the recognition of curium-transferrin complexes by the cognate transferrin receptor. In addition to providing the first protein-curium spectroscopic characterization, these studies prove that transferrin receptor-mediated endocytosis is a viable mechanism of intracellular entry for trivalent actinides such as curium and provide a new tool utilizing the specific luminescence of curium for the determination of other biological actinide transport mechanisms. PMID:23363005

  2. Sensitizing curium luminescence through an antenna protein to investigate biological actinide transport mechanisms.

    PubMed

    Sturzbecher-Hoehne, Manuel; Goujon, Christophe; Deblonde, Gauthier J-P; Mason, Anne B; Abergel, Rebecca J

    2013-02-20

    Worldwide stocks of actinides and lanthanide fission products produced through conventional nuclear spent fuel are increasing continuously, resulting in a growing risk of environmental and human exposure to these toxic radioactive metal ions. Understanding the biomolecular pathways involved in mammalian uptake, transport and storage of these f-elements is crucial to the development of new decontamination strategies and could also be beneficial to the design of new containment and separation processes. To start unraveling these pathways, our approach takes advantage of the unique spectroscopic properties of trivalent curium. We clearly show that the human iron transporter transferrin acts as an antenna that sensitizes curium luminescence through intramolecular energy transfer. This behavior has been used to describe the coordination of curium within the two binding sites of the protein and to investigate the recognition of curium-transferrin complexes by the cognate transferrin receptor. In addition to providing the first protein-curium spectroscopic characterization, these studies prove that transferrin receptor-mediated endocytosis is a viable mechanism of intracellular entry for trivalent actinides such as curium and provide a new tool utilizing the specific luminescence of curium for the determination of other biological actinide transport mechanisms. PMID:23363005

  3. Preparation of curium-americium oxide microspheres by resin-bead loading

    SciTech Connect

    Chattin, F.R.; Benker, D.E.; Lloyd, M.H.; Orr, P.B.; Ross, R.G.; Wiggins, J.T.

    1980-01-01

    Resin-bead loading and calcination techniques have been used to produce all curium and americium oxide feed material (about 2.2 kg) for HFIR targets since 1971. The process based on Dowex 50W resin has progressed from a series of test runs, through special production runs, into routine production in permanent equipment beginning in 1975. Key attributes of this process are its reliability, high yields, and ease of operation. The process is suited for remote operation in hot cells. Yields approaching 95% are routinely obtained and only one unacceptable product has been generated during routine production operations. There have been no problems in fabricating targets from this oxide or in the subsequent irradiation of these targets. The present scale of production of 150 to 250 g/y supplies the present need and is comparable with the level of other chemical process operations at TRU. Since the annual production is accomplished in two 8 to 12 day periods, there has been no reason to consider further scale-up. However, the rate of production could easily be doubled by simply adding a second set of calcination equipment.

  4. Separation of americium from curium by oxidation and ion exchange.

    PubMed

    Burns, Jonathan D; Shehee, Thomas C; Clearfield, Abraham; Hobbs, David T

    2012-08-21

    Nuclear energy has the potential to be a clean alternative to fossil fuels, but in order for it to play a major role in the US, many questions about the back end of the fuel cycle must be addressed. One of these questions is the difficult separation of americium from curium. Here, we report the oxidation of Am in two systems, perchloric acid and nitric acid and the affect of changing the acid has on the oxidation. K(d) values were observed and a direct separation factor was calculated and was seen to be as high as 20 for four metal(IV) pillared phosphate phosphonate inorganic organic hybrid ion exchange materials. These ion exchangers are characterized by very low selectivity for cations with low charge but extremely high uptake of ions of high charge. PMID:22827724

  5. Applications of curium measurements for safeguarding at large-scale reprocessing plants

    SciTech Connect

    Rinard, P.M.; Menlove, H.O.

    1997-08-01

    Safeguarding the plutonium passing through a large-scale reprocessing plant (such as one with 800 t of uranium per year) involves nondestructive assay measurements for plutonium at key points. The gamma-ray and neutron signals from the plutonium are generally hidden by the much larger backgrounds from fission products and actinides, so indirect measurements are routinely used. The intense neutron emission rate from spent fuel is from curium. In a spent fuel assembly at the head-end of a plant, the curium neutrons are used to deduce the amount of plutonium present. Coincidence and multiplicity counting are alternative ways to measure neutrons from spent fuel; they have advantages over total neutron counting in certain conditions and offer new opportunities for examining assemblies. New uses for measurements of curium`s neutrons are proposed to safeguard waste streams. From a year`s work at a large-scale plant, 4 to 7 kg of plutonium can remain in leached hulls and 4 to 22 kg of plutonium can remain in the vitrified high-level liquid waste. While the plutonium in these wastes has the safeguards advantage of being dilute, it is important to verify (a) that the many kilograms involved are in fact present and (b) that the declared masses are not higher than the actual amounts so that more concentrated plutonium cannot pass through the plant by masquerading as waste. Curium measurements on spent fuel assemblies, the accountability tank, and leached hulls would form a safeguards system around all the inputs and outputs of a plant`s head-end where the plutonium is always intimately mixed with the curium. A neutron measurement of the vitrified waste would help identify the presence of a diversion path upstream because essentially all of the curium measured in the spent fuel assemblies should also be found in the vitrified waste (on a batch basis). 7 refs., 4 figs.

  6. Density of simulated americium/curium melter feed solution

    SciTech Connect

    Rudisill, T.S.

    1997-09-22

    Vitrification will be used to stabilize an americium/curium (Am/Cm) solution presently stored in F-Canyon for eventual transport to Oak Ridge National Laboratory and use in heavy isotope production programs. Prior to vitrification, a series of in-tank oxalate precipitation and nitric/oxalic acid washes will be used to separate these elements and lanthanide fission products from the bulk of the uranium and metal impurities present in the solution. Following nitric acid dissolution and oxalate destruction, the solution will be denitrated and evaporated to a dissolved solids concentration of approximately 100 g/l (on an oxide basis). During the Am/Cm vitrification, an airlift will be used to supply the concentrated feed solution to a constant head tank which drains through a filter and an in-line orifice to the melter. Since the delivery system is sensitive to the physical properties of the feed, a simulated solution was prepared and used to measure the density as a function of temperature between 20 to 70{degrees} C. The measured density decreased linearly at a rate of 0.0007 g/cm3/{degree} C from an average value of 1.2326 g/cm{sup 3} at 20{degrees} C to an average value of 1.1973g/cm{sup 3} at 70{degrees} C.

  7. Oxidation of trivalent americium, curium, and terbium in solutions of sodium paratungstate

    SciTech Connect

    Fedoseev, A.M.; Krot, N.N.; Spitsyn, V.I.

    1986-09-01

    In the further study of the behavior of the actinides and lanthanides in solutions of heteropoly-compounds, the authors succeed in finding conditions under which the formation of americium (IV), curium (IV), and terbium (IV) decatungstates is observed. The results of experiments along this line are brieflyoutlined. It is shown that trivalent americium, curium, and terbium are oxidzed by heating with persulfate not only in solutions ofunsaturated heteropolytungstates but also in solutions of isopoly-compounds of tungsten. However, the degree of oxidation of curium and terbium (III) in the latter case is appreciably lover. In addition to persulfate ions, ozone can be used for the oxidation of americium (III) in solutions of sodium paratungstate.

  8. Impact of environmental curium on plutonium migration and isotopic signatures.

    PubMed

    Kurosaki, Hiromu; Kaplan, Daniel I; Clark, Sue B

    2014-12-01

    Plutonium (Pu), americium (Am), and curium (Cm) activities were measured in sediments from a former radioactive waste disposal basin located on the Savannah River Site, South Carolina, and in subsurface aquifer sediments collected downgradient from the basin. In situ Kd values (Pu concentration ratio of sediment/groundwater) derived from this field data and previously reported groundwater concentration data compared well to laboratory Kd values reported in the literature. Pu isotopic signatures confirmed multiple sources of Pu contamination. The ratio of (240)Pu/(239)Pu was appreciably lower for sediment samples compared to the associated groundwater. This isotopic ratio difference may be explained by the following: (1) (240)Pu produced by decay of (244)Cm may exist predominantly in high oxidation states (Pu(V)O2(+) and Pu(VI)O2(2+)) compared to Pu derived from the disposed waste effluents, and (2) oxidized forms of Pu sorb less to sediments than reduced forms of Pu. Isotope-specific Kd values calculated from measured Pu activities in the sediments and groundwater indicated that (240)Pu, which is derived primarily from the decay of (244)Cm, had a value of 10 ± 2 mL g(-1), whereas (239)Pu originating from the waste effluents discharged at the site had a value of 101 ± 8 mL g(-1). One possible explanation for the isotope-specific sorption behavior is that (240)Pu likely existed in the weaker sorbing oxidation states, +5 or +6, than (239)Pu, which likely existed in the +3 or +4 oxidation states. Consequently, remediation strategies for radioactively contaminated systems must consider not only the discharged contaminants but also their decay products. In this case, mitigation of Cm as well as Pu will be required to completely address Pu migration from the source term. PMID:25350948

  9. X-ray Emission Wavelengths of Argon, Krypton, Xenon, and Curium

    NASA Astrophysics Data System (ADS)

    Kleykamp, H.

    1992-03-01

    The wavelengths of the L series of argon, krypton and xenon, the K series of argon, and the M series of curium were measured by means of wavelength dispersive X-ray microanalysis. The specimens for the investigations were TiC layers which had been HF sputtered under reduced argon pressure by the PVD method, krypton and xenon implanted zeolites, and a curium doped borosilicate glass. The obtained relative intensities of the X-ray emission lines were normalized to the maximum intensity of the line of the respective series

  10. 2,4,6-Trichlorophenol

    Integrated Risk Information System (IRIS)

    2,4,6 - Trichlorophenol ; CASRN 88 - 06 - 2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for Noncarcino

  11. 32 CFR 246.7 - Information requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Information requirements. 246.7 Section 246.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.7 Information requirements....

  12. 32 CFR 246.7 - Information requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Information requirements. 246.7 Section 246.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.7 Information requirements....

  13. 32 CFR 246.7 - Information requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Information requirements. 246.7 Section 246.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.7 Information requirements....

  14. 32 CFR 246.2 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Applicability. 246.2 Section 246.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.2 Applicability. This part applies...

  15. 32 CFR 246.2 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Applicability. 246.2 Section 246.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.2 Applicability. This part applies...

  16. 32 CFR 246.2 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Applicability. 246.2 Section 246.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.2 Applicability. This part applies...

  17. 32 CFR 246.2 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Applicability. 246.2 Section 246.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.2 Applicability. This part applies...

  18. 32 CFR 246.2 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Applicability. 246.2 Section 246.2 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.2 Applicability. This part applies...

  19. 32 CFR 246.7 - Information requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Information requirements. 246.7 Section 246.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.7 Information requirements....

  20. 32 CFR 246.7 - Information requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Information requirements. 246.7 Section 246.7 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.7 Information requirements....

  1. 42 CFR 431.246 - Corrective action.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Corrective action. 431.246 Section 431.246 Public... Recipients Procedures § 431.246 Corrective action. The agency must promptly make corrective payments, retroactive to the date an incorrect action was taken, and, if appropriate, provide for admission...

  2. 48 CFR 2453.246 - Quality Assurance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Quality Assurance. 2453.246 Section 2453.246 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CLAUSES AND FORMS FORMS Prescription of Forms 2453.246 Quality Assurance....

  3. 40 CFR 246.100 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Scope. 246.100 Section 246.100 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES General Provisions § 246.100 Scope. (a) These guidelines are applicable to the source separation of...

  4. 12 CFR 246.4 - Assessments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Assessments. 246.4 Section 246.4 Banks and...) SUPERVISION AND REGULATION ASSESSMENTS OF FEES (REGULATION TT) § 246.4 Assessments. (a) Assessment. Each assessed company shall pay to the Board an assessment for any assessment period for which the...

  5. 48 CFR 246.705 - Limitations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Limitations. 246.705 Section 246.705 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.705 Limitations. (a) In addition...

  6. 24 CFR 246.21 - Rental charges.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Rental charges. 246.21 Section 246.21 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL Subsidized Insured Projects § 246.21 Rental charges. The Department finds that it is necessary...

  7. 24 CFR 246.30 - Rental charges.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Rental charges. 246.30 Section 246.30 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL HUD-Owned Projects § 246.30 Rental charges. The Department has exclusive jurisdiction over...

  8. 24 CFR 246.5 - Rental charges.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Rental charges. 246.5 Section 246.5 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... Unsubsidized Insured Projects § 246.5 Rental charges. The Department will generally not interfere in...

  9. 24 CFR 246.5 - Rental charges.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Rental charges. 246.5 Section 246.5 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... Unsubsidized Insured Projects § 246.5 Rental charges. The Department will generally not interfere in...

  10. 24 CFR 246.21 - Rental charges.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Rental charges. 246.21 Section 246.21 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL Subsidized Insured Projects § 246.21 Rental charges. The Department finds that it is necessary...

  11. 24 CFR 246.30 - Rental charges.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Rental charges. 246.30 Section 246.30 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL HUD-Owned Projects § 246.30 Rental charges. The Department has exclusive jurisdiction over...

  12. 7 CFR 246.3 - Administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Administration. 246.3 Section 246.3 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN General § 246.3 Administration. (a) Delegation...

  13. 7 CFR 246.3 - Administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Administration. 246.3 Section 246.3 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN General § 246.3 Administration. (a) Delegation...

  14. 7 CFR 246.21 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Investigations. 246.21 Section 246.21 Agriculture... Monitoring and Review § 246.21 Investigations. (a) Authority. The Department may make an investigation of any allegation of noncompliance with this part and FNS guidelines and instructions. The investigation may...

  15. 7 CFR 246.21 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Investigations. 246.21 Section 246.21 Agriculture... Monitoring and Review § 246.21 Investigations. (a) Authority. The Department may make an investigation of any allegation of noncompliance with this part and FNS guidelines and instructions. The investigation may...

  16. 24 CFR 246.5 - Rental charges.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Rental charges. 246.5 Section 246.5 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... Unsubsidized Insured Projects § 246.5 Rental charges. The Department will generally not interfere in...

  17. 24 CFR 246.30 - Rental charges.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Rental charges. 246.30 Section 246.30 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL HUD-Owned Projects § 246.30 Rental charges. The Department has exclusive jurisdiction over...

  18. 24 CFR 246.21 - Rental charges.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Rental charges. 246.21 Section 246.21 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL Subsidized Insured Projects § 246.21 Rental charges. The Department finds that it is necessary...

  19. 24 CFR 246.5 - Rental charges.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Rental charges. 246.5 Section 246.5 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... Unsubsidized Insured Projects § 246.5 Rental charges. The Department will generally not interfere in...

  20. 24 CFR 246.30 - Rental charges.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Rental charges. 246.30 Section 246.30 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL HUD-Owned Projects § 246.30 Rental charges. The Department has exclusive jurisdiction over...

  1. 24 CFR 246.5 - Rental charges.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Rental charges. 246.5 Section 246.5 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... Unsubsidized Insured Projects § 246.5 Rental charges. The Department will generally not interfere in...

  2. 24 CFR 246.30 - Rental charges.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Rental charges. 246.30 Section 246.30 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL HUD-Owned Projects § 246.30 Rental charges. The Department has exclusive jurisdiction over...

  3. 24 CFR 246.21 - Rental charges.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Rental charges. 246.21 Section 246.21 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL Subsidized Insured Projects § 246.21 Rental charges. The Department finds that it is necessary...

  4. 24 CFR 246.21 - Rental charges.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Rental charges. 246.21 Section 246.21 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... CONTROL Subsidized Insured Projects § 246.21 Rental charges. The Department finds that it is necessary...

  5. 48 CFR 2453.246 - Quality Assurance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Quality Assurance. 2453.246 Section 2453.246 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CLAUSES AND FORMS FORMS Prescription of Forms 2453.246 Quality Assurance....

  6. National Low-Level Waste Management Program radionuclide report series. Volume 13, Curium-242

    SciTech Connect

    Adams, J.P.

    1995-08-01

    This report, Volume 13 of the National Low-Level Waste Management Program Radionuclide Report Series, discusses the radiological and chemical characteristics of curium-242 ({sup 242}Cm). This report also includes discussions about waste types and forms in which {sup 242}Cm can be found and {sup 242}Cm behavior in the environment and in the human body.

  7. Safety analysis report for packaging (SARP) of the Oak Ridge National Laboratory. TRU curium shipping container

    SciTech Connect

    Box, W.D.; Klima, B.B.; Seagren, R.D.; Shappert, L.B.; Aramayo, G.A.

    1980-06-01

    An analytical evaluation of the Oak Ridge National Laboratory Transuranium (TRU) Curium Shipping Container was made to demonstrate its compliance with the regulations governing offsite shipment of packages containing radioactive material. The evaluation encompassed five primary categories: structural integrity, thermal resistance, radiation shielding, nuclear criticality safety, and quality assurance. The results of the evaluation show that the container complies with the applicable regulations.

  8. Separation of Americium in High Oxidation States from Curium Utilizing Sodium Bismuthate.

    PubMed

    Richards, Jason M; Sudowe, Ralf

    2016-05-01

    A simple separation of americium from curium would support closure of the nuclear fuel cycle, assist in nuclear forensic analysis, and allow for more accurate measurement of neutron capture properties of (241)Am. Methods for the separation of americium from curium are however complicated and time-consuming due to the similar chemical properties of these elements. In this work a novel method for the separation of americium from curium in nitric acid media was developed using sodium bismuthate to perform both the oxidation and separation. Sodium bismuthate is shown to be a promising material for performing a simple and rapid separation. Curium is more strongly retained than americium on the undissolved sodium bismuthate at nitric acid concentrations below 1.0 M. A separation factor of ∼90 was obtained in 0.1 M nitric acid. This separation factor is achieved within the first minute of contact and is maintained for at least 2 h of contact. Separations using sodium bismuthate were performed using solid-liquid extraction as well as column chromatography. PMID:27079565

  9. 43 CFR 2.46 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Definitions. 2.46 Section 2.46 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT Privacy Act § 2.46 Definitions. (a) Act. As used in this subpart, “Act” means section 3 of the Privacy Act, 5 U.S.C. 552a. (b) Bureau. For...

  10. Importance of counteranions on the hydration structure of the curium ion

    SciTech Connect

    Atta Fynn, Raymond; Bylaska, Eric J.; De Jong, Wibe A.

    2013-07-04

    Using density functional theory based ab initio molecular dynamics and metadynamics we show that counter ions can trigger noticeable changes in the hydration shell structure of the curium ion. The free energies of curium-water coordination and the solvent hydrogen bond (HB) lifetimes in the absence and presence the counter anions predict that chloride and bromide counter anions strengthen the first shell and consequently the 8-fold coordination state is dominant by at least 98%. In contrast, the perchlorate counter anions are found to weaken the coordination shell and the HB network, with the 9-fold and 8-fold states existing in an 8:1 ratio, which is in good agreement with reported 9:1 ratio seen in time resolved fluorescence spectroscopy experiments. To our knowledge this is the first time molecular simulations have shown that counter anions can directly affect the first hydration shell structure of a cation.

  11. Separating curium and californium on experimental batches of solid extractants containing D2EHPA

    SciTech Connect

    Dedov, V.B.; Trukhlyaev, P.S.; Kalinichenko, B.S.; Shvetsov, I.K.

    1987-05-01

    Data are given on the extraction parameters for D2EHPA-impregnated solids made by a new method of binding the reagent to the matrix in the synthesis of a styrene-divinylbenzene copolymer by suspension polymerization. Results are given on separating curium and californium with these D2EHPA materials under dynamic conditions. The optimum separation conditions are given, where one obtains virtually pure fractions of the two elements.

  12. 7 CFR 246.8 - Nondiscrimination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Nondiscrimination. 246.8 Section 246.8 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN Participant Eligibility §...

  13. 7 CFR 246.8 - Nondiscrimination.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Nondiscrimination. 246.8 Section 246.8 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN Participant Eligibility §...

  14. 21 CFR 522.246 - Butorphanol.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Butorphanol. 522.246 Section 522.246 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... Butorphanol. (a) Specifications. Each milliliter of solution contains butorphanol (as butorphanol tartrate)...

  15. 48 CFR 246.270-2 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...— (1) Fire protection; (2) Structural integrity; (3) Electrical systems; (4) Plumbing; (5) Water... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Policy. 246.270-2 Section 246.270-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

  16. 48 CFR 246.270-2 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...— (1) Fire protection; (2) Structural integrity; (3) Electrical systems; (4) Plumbing; (5) Water... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Policy. 246.270-2 Section 246.270-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

  17. 48 CFR 246.270-2 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...— (1) Fire protection; (2) Structural integrity; (3) Electrical systems; (4) Plumbing; (5) Water... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Policy. 246.270-2 Section 246.270-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT...

  18. 50 CFR 665.246 - Gear identification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Gear identification. 665.246 Section 665.246 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES IN THE WESTERN PACIFIC Hawaii Fisheries §...

  19. 7 CFR 246.11 - Nutrition education.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Nutrition education. 246.11 Section 246.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND...

  20. 7 CFR 246.11 - Nutrition education.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Nutrition education. 246.11 Section 246.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND...

  1. 7 CFR 246.11 - Nutrition education.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Nutrition education. 246.11 Section 246.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND...

  2. 7 CFR 246.11 - Nutrition education.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Nutrition education. 246.11 Section 246.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND...

  3. 7 CFR 246.11 - Nutrition education.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Nutrition education. 246.11 Section 246.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND...

  4. 50 CFR 665.246 - Gear identification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Gear identification. 665.246 Section 665.246 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC... Gear identification. In Permit Area 1, the vessel's official number must be marked legibly on all...

  5. 48 CFR 246.701 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 52.246-20, Warranty of Services, includes the execution of an official document (e.g., DD Form 250... used in this subpart, means any condition or characteristic in any supply or service furnished by the... OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.701 Definitions. Acceptance,...

  6. 48 CFR 246.408-70 - Subsistence.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Subsistence. 246.408-70 Section 246.408-70 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance...

  7. 48 CFR 246.472 - Inspection stamping.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Inspection stamping. 246.472 Section 246.472 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance...

  8. 7 CFR 246.20 - Audits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Audits. 246.20 Section 246.20 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND...

  9. 48 CFR 246.406 - Foreign governments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Foreign governments. 246..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.406 Foreign governments. (1) Quality assurance among North Atlantic Treaty Organization (NATO) countries....

  10. 48 CFR 246.406 - Foreign governments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Foreign governments. 246..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.406 Foreign governments. (1) Quality assurance among North Atlantic Treaty Organization (NATO) countries....

  11. 48 CFR 246.406 - Foreign governments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Foreign governments. 246..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.406 Foreign governments. (1) Quality assurance among North Atlantic Treaty Organization (NATO) countries....

  12. 48 CFR 246.406 - Foreign governments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Foreign governments. 246..., DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.406 Foreign governments. (1) Quality assurance among North Atlantic Treaty Organization (NATO) countries....

  13. 48 CFR 246.470 - Government contract quality assurance actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... quality assurance actions. 246.470 Section 246.470 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.470 Government contract quality assurance actions....

  14. Determination of Atto- to Femtogram Levels of Americium and Curium Isotopes in Large-Volume Urine Samples by Compact Accelerator Mass Spectrometry.

    PubMed

    Dai, Xiongxin; Christl, Marcus; Kramer-Tremblay, Sheila; Synal, Hans-Arno

    2016-03-01

    Ultralow level analysis of actinides in urine samples may be required for dose assessment in the event of internal exposures to these radionuclides at nuclear facilities and nuclear power plants. A new bioassay method for analysis of sub-femtogram levels of Am and Cm in large-volume urine samples was developed. Americium and curium were co-precipitated with hydrous titanium oxide from the urine matrix and purified by column chromatography separation. After target preparation using mixed titanium/iron oxides, the final sample was measured by compact accelerator mass spectrometry. Urine samples spiked with known quantities of Am and Cm isotopes in the range of attogram to femtogram levels were measured for method evaluation. The results are in good agreement with the expected values, demonstrating the feasibility of compact accelerator mass spectrometry (AMS) for the determination of minor actinides at the levels of attogram/liter in urine samples to meet stringent sensitivity requirements for internal dosimetry assessment. PMID:26822907

  15. Electron-capture delayed fission in {sup 246}Es

    SciTech Connect

    Shaughnessy, D.A.; Gregorich, K.E.; Hendricks, M.B.; Lane, M.R.

    1997-12-31

    We have extended our systematic study of electron-capture delayed fission (ECDF) in neutron-deficient isotopes to {sup 246}Es. The {sup 246}Es was produced at the 88 Inch Cyclotron at Lawrence Berkeley National Laboratory via the {sup 249}Cf(p,xn){sup 250-x}Es reaction with 37 MeV protons. There were 19 {sup 249}Cf targets used simultaneously in our light ion multiple (LIM) target system. Alpha particles and fission fragments were detected in our rotating wheel system. In some experiments, TTA extractions were performed to remove interfering activities. The chemically separated samples were positioned between a solid-state particle detector and two x-rays detectors. This configuration enabled us to look for fissions in coincidence with K x-rays following electron-capture. Our measured production cross section of 13 {+-} 5 {mu}b for {sup 246}Es was much lower than the cross section predicted by a neutron evaporation code. The probability of delayed fission was determined from the number of x-ray/fission coincidences measured.

  16. 40 CFR 246.202-1 - Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.202-1 Requirement. Any commercial establishment generating 10 or more tons of waste corrugated containers per month...

  17. 48 CFR 246.710 - Contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.710 Contract clauses. (1) Use a... contracts that include the clause at 252.227-7013, Rights in Technical Data and Computer Software,...

  18. Type B investigation report of curium-244 exposure at the ORNL TRU Facility, January 15, 1986

    SciTech Connect

    Love, G.L.; Butler, H.M.; Duncan, D.T.; Oakes, T.W.

    1986-04-01

    This Type B Investigative Report provides an evaluation of relevant events and activities that led to, were a part of, or resulted from the release of curium-244 in the Building 7920 facility at ORNL in January 1986. Impacts have been evaluated with respect to employee exposures and the costs and loss of productivity resulting from increased bioassay analyses and activities of investigative committees. Management systems evaluated include (1) training of employees performing lab analyses, (2) adherence to procedures, and (3) response to unusual circumstances.

  19. 48 CFR 252.246-7002 - Warranty of construction (Germany).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (Germany). 252.246-7002 Section 252.246-7002 Federal Acquisition Regulations System DEFENSE ACQUISITION... of Provisions And Clauses 252.246-7002 Warranty of construction (Germany). As prescribed in 246.710(4), use the following clause: Warranty of Construction (Germany) (JUN 1997) (a) In addition to any...

  20. Actinide production from xenon bombardments of curium-248

    SciTech Connect

    Welch, R.B.

    1985-01-01

    Production cross sections for many actinide nuclides formed in the reaction of /sup 129/Xe and /sup 132/Xe with /sup 248/Cm at bombarding energies slightly above the coulomb barrier were determined using radiochemical techniques to isolate these products. These results are compared with cross sections from a /sup 136/Xe + /sup 248/Cm reaction at a similar energy. When compared to the reaction with /sup 136/Xe, the maxima in the production cross section distributions from the more neutron deficient projectiles are shifted to smaller mass numbers, and the total cross section increases for the production of elements with atomic numbers greater than that of the target, and decreases for lighter elements. These results can be explained by use of a potential energy surface (PES) which illustrates the effect of the available energy on the transfer of nucleons and describes the evolution of the di-nuclear complex, an essential feature of deep-inelastic reactions (DIR), during the interaction. The other principal reaction mechanism is the quasi-elastic transfer (QE). Analysis of data from a similar set of reactions, /sup 129/Xe, /sup 132/Xe, and /sup 136/Xe with /sup 197/Au, aids in explaining the features of the Xe + Cm product distributions, which are additionally affected by the depletion of actinide product yields due to deexcitation by fission. The PES is shown to be a useful tool to predict the general features of product distributions from heavy ion reactions.

  1. RAPID METHOD FOR PLUTONIUM, AMERICIUM AND CURIUM IN VERY LARGE SOIL SAMPLES

    SciTech Connect

    Maxwell, S

    2007-01-08

    The analysis of actinides in environmental soil and sediment samples is very important for environmental monitoring. There is a need to measure actinide isotopes with very low detection limits. A new, rapid actinide separation method has been developed and implemented that allows the measurement of plutonium, americium and curium isotopes in very large soil samples (100-200 g) with high chemical recoveries and effective removal of matrix interferences. This method uses stacked TEVA Resin{reg_sign}, TRU Resin{reg_sign} and DGA-Resin{reg_sign} cartridges from Eichrom Technologies (Darien, IL, USA) that allows the rapid separation of plutonium (Pu), americium (Am), and curium (Cm) using a single multistage column combined with alpha spectrometry. The method combines an acid leach step and innovative matrix removal using cerium fluoride precipitation to remove the difficult soil matrix. This method is unique in that it provides high tracer recoveries and effective removal of interferences with small extraction chromatography columns instead of large ion exchange resin columns that generate large amounts of acid waste. By using vacuum box cartridge technology with rapid flow rates, sample preparation time is minimized.

  2. Investigation of {sup 246}Fm : in-beam spectroscopy at the limits

    SciTech Connect

    Piot, J.; Dorvaux, O.; Gall, B. J.-P.; Rubert, J.; Greenlees, P. T.; Grahn, T.; Herzan, A.; Jakobsson, U.; Jones, P.; Julin, R.; Juutinen, S.; Ketelhut, S.; Leino, M.; Nieminen, P.; Peura, P.; Rahkila, P.; Rinta-Antila, S.; Ruotsalainen, P.; Sandzelius, M.; Saren, J.

    2011-10-28

    The structure of {sup 246}Fm has been investigated using in-beam {gamma}-ray spectroscopy. The experiment was performed at the University of Jyvaeskylae using JUROGAM 2 coupled to RITU and GREAT. The {sup 246}Fm nuclei were produced using a 186 MeV beam of {sup 40}Ar impinging on a target of {sup 208}Pb. JUROGAM 2 was fully instrumented with TNT2D digital acquisition cards. The use of digital acquisition cards and a rotating target allowed for unprecedented beam intensities up to 71 particle-nanoamperes for prompt {gamma}-ray spectroscopy. With all these major advances for spectroscopy a rotational band is observed for the first time in {sup 246}Fm and discussed here.

  3. Circularly Polarized Luminescence of Curium: A New Characterization of the 5f Actinide Complexes

    PubMed Central

    Law, Ga-Lai; Andolina, Christopher M.; Xu, Jide; Luu, Vinh; Rutkowski, Philip X.; Muller, Gilles; Shuh, David K.; Gibson, John K.; Raymond, Kenneth N.

    2012-01-01

    A key distinction between the lanthanide (4f) and actinide (5f) transition elements is the increased role of f-orbital covalent bonding in the latter. Circularly polarized luminescence (CPL) is an uncommon but powerful spectroscopy which probes the electronic structure of chiral, luminescent complexes or molecules. While there are many examples of CPL spectra for the lanthanides, this report is the first for an actinide. Two chiral, octadentate chelating ligands based on orthoamide phenol (IAM) were used to complex curium(III). While the radioactivity kept the amount of material limited to micromole amounts, the spectra of the highly luminescent complexes showed significant emission peak-shifts between the different complexes, consistent with ligand field effects previously observed in luminescence spectra. PMID:22920726

  4. 48 CFR 246.408-71 - Aircraft.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Aircraft. 246.408-71... Aircraft. (a) The Federal Aviation Administration (FAA) has certain responsibilities and prerogatives in connection with some commercial aircraft and of aircraft equipment and accessories (Pub. L. 85-726 (72...

  5. 48 CFR 246.408-71 - Aircraft.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Aircraft. 246.408-71... Aircraft. (a) The Federal Aviation Administration (FAA) has certain responsibilities and prerogatives in connection with some commercial aircraft and of aircraft equipment and accessories (Pub. L. 85-726 (72...

  6. 48 CFR 246.408-71 - Aircraft.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Aircraft. 246.408-71... Aircraft. (a) The Federal Aviation Administration (FAA) has certain responsibilities and prerogatives in connection with some commercial aircraft and of aircraft equipment and accessories (Pub. L. 85-726 (72...

  7. 50 CFR 622.246 - Area closures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF COMMERCE FISHERIES OF THE CARIBBEAN, GULF OF MEXICO, AND SOUTH ATLANTIC Golden Crab Fishery of the South Atlantic Region § 622.246 Area closures. (a) Golden crab trap closed areas. In the golden crab northern zone, a golden crab trap may not be deployed in waters less than 900 ft (274 m) deep....

  8. 50 CFR 622.246 - Area closures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF COMMERCE FISHERIES OF THE CARIBBEAN, GULF OF MEXICO, AND SOUTH ATLANTIC Golden Crab Fishery of the South Atlantic Region § 622.246 Area closures. (a) Golden crab trap closed areas. In the golden crab northern zone, a golden crab trap may not be deployed in waters less than 900 ft (274 m) deep....

  9. 43 CFR 24.6 - Cooperative agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.6 Cooperative agreements. (a) By reason of the Congressional policy (e.g., Fish and Wildlife Coordination Act of 1956) of State-Federal cooperation and coordination in the area of fish and wildlife conservation, State and Federal agencies have...

  10. 43 CFR 24.6 - Cooperative agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.6 Cooperative agreements. (a) By reason of the Congressional policy (e.g., Fish and Wildlife Coordination Act of 1956) of State-Federal cooperation and coordination in the area of fish and wildlife conservation, State and Federal agencies have...

  11. 43 CFR 24.6 - Cooperative agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.6 Cooperative agreements. (a) By reason of the Congressional policy (e.g., Fish and Wildlife Coordination Act of 1956) of State-Federal cooperation and coordination in the area of fish and wildlife conservation, State and Federal agencies have...

  12. 43 CFR 24.6 - Cooperative agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... WILDLIFE POLICY: STATE-FEDERAL RELATIONSHIPS § 24.6 Cooperative agreements. (a) By reason of the Congressional policy (e.g., Fish and Wildlife Coordination Act of 1956) of State-Federal cooperation and coordination in the area of fish and wildlife conservation, State and Federal agencies have...

  13. 32 CFR 246.3 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.3 Definitions. (a) Adverse Conditions... publisher of the Stars and Stripes produced by that organization. (c) S&S Management Action Group (MAG) and... issues. Neither the DoD S&S Steering Committee, nor the S&S MAG, involve themselves in Stars and...

  14. 32 CFR 246.3 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.3 Definitions. (a) Adverse Conditions... publisher of the Stars and Stripes produced by that organization. (c) S&S Management Action Group (MAG) and... issues. Neither the DoD S&S Steering Committee, nor the S&S MAG, involve themselves in Stars and...

  15. 32 CFR 246.3 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.3 Definitions. (a) Adverse Conditions... publisher of the Stars and Stripes produced by that organization. (c) S&S Management Action Group (MAG) and... issues. Neither the DoD S&S Steering Committee, nor the S&S MAG, involve themselves in Stars and...

  16. 32 CFR 246.3 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.3 Definitions. (a) Adverse Conditions... publisher of the Stars and Stripes produced by that organization. (c) S&S Management Action Group (MAG) and... issues. Neither the DoD S&S Steering Committee, nor the S&S MAG, involve themselves in Stars and...

  17. 32 CFR 246.3 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS § 246.3 Definitions. (a) Adverse Conditions... publisher of the Stars and Stripes produced by that organization. (c) S&S Management Action Group (MAG) and... issues. Neither the DoD S&S Steering Committee, nor the S&S MAG, involve themselves in Stars and...

  18. 48 CFR 246.102 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE General 246.102 Policy. Departments and agencies shall also— (1) Develop and manage a systematic, cost-effective Government contract quality assurance program to ensure that contract performance conforms to specified requirements. Apply Government quality...

  19. 48 CFR 246.401 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.401 General. The requirement for a quality assurance surveillance plan shall be addressed and documented in the contract file... services, the contracting officer should prepare a quality assurance surveillance plan to...

  20. 2,4,6-Trinitrotoluene (TNT)

    Integrated Risk Information System (IRIS)

    2,4,6 - Trinitrotoluene ( TNT ) ; CASRN 118 - 96 - 7 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data , as outlined in the IRIS assessment development process . Sections I ( Health Hazard Assessments for N

  1. 48 CFR 246.408-71 - Aircraft.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Aircraft. 246.408-71... Aircraft. (a) The Federal Aviation Administration (FAA) has certain responsibilities and prerogatives in connection with some commercial aircraft and of aircraft equipment and accessories (Pub. L. 85-726 (72...

  2. Aqueous complexes for efficient size-based separation of americium from curium.

    PubMed

    Jensen, Mark P; Chiarizia, Renato; Shkrob, Ilya A; Ulicki, Joseph S; Spindler, Brian D; Murphy, Daniel J; Hossain, Mahmun; Roca-Sabio, Adrián; Platas-Iglesias, Carlos; de Blas, Andrés; Rodríguez-Blas, Teresa

    2014-06-16

    Complexation of the adjacent actinide ions americium(III) and curium(III) by the ligand N,N'-bis[(6-carboxy-2-pyridyl)methyl]-1,10-diaza-18-crown-6 (H2bp18c6) in aqueous solution was studied to quantify and characterize its americium/curium selectivity. Liquid-liquid extraction and spectrophotometric titration indicated the presence of both fully deprotonated and monoprotonated complexes, An(bp18c6)(+) and An(Hbp18c6)(2+) (An = Am or Cm), at the acidities that would be encountered when treating nuclear wastes. The stability constants of the complexes in 1 M NaNO3 determined using competitive complexation were log β101 = 15.49 ± 0.06 for Am and 14.88 ± 0.03 for Cm, indicating a reversal of the usual order of complex stability, where ligands bind the smaller Cm(III) ion more tightly than Am(III). The Am/Cm selectivity of bp18c6(2-) that is defined by the ratio of the Am and Cm stability constants (β101 Am/β101 Cm = 4.1) is the largest reported so far for binary An(III)-ligand complexes. Theoretical density functional theory calculations using the B3LYP functional suggest that the ligand's size-selectivity for larger 4f- and 5f-element cations arises from steric constraints in the crown ether ring. Enhanced 5f character in molecular orbitals involving actinide-nitrogen interactions is predicted to favor actinide(III) complexation by bp18c6(2-) over the complexation of similarly sized lanthanide(III) cations. PMID:24890863

  3. 7 CFR 246.28 - OMB control numbers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... information collection requirements in 7 CFR part 246 by the Office of Management and Budget pursuant to the Paperwork Reduction Act of 1980, Pub. L. 96-511. 7 CFR part 246 section where requirements are...

  4. 7 CFR 246.28 - OMB control numbers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... information collection requirements in 7 CFR part 246 by the Office of Management and Budget pursuant to the Paperwork Reduction Act of 1980, Pub. L. 96-511. 7 CFR part 246 section where requirements are...

  5. 40 CFR 246.200 - High-grade paper recovery.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false High-grade paper recovery. 246.200 Section 246.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE... paper recovery....

  6. 40 CFR 246.200 - High-grade paper recovery.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false High-grade paper recovery. 246.200 Section 246.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE... paper recovery....

  7. 40 CFR 246.200 - High-grade paper recovery.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true High-grade paper recovery. 246.200 Section 246.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE... paper recovery....

  8. 40 CFR 246.200 - High-grade paper recovery.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false High-grade paper recovery. 246.200 Section 246.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE... paper recovery....

  9. 40 CFR 246.200 - High-grade paper recovery.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false High-grade paper recovery. 246.200 Section 246.200 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE... paper recovery....

  10. Application of curium measurements for safeguarding at reprocessing plants. Study 1: High-level liquid waste and Study 2: Spent fuel assemblies and leached hulls

    SciTech Connect

    Rinard, P.M.; Menlove, H.O.

    1996-03-01

    In large-scale reprocessing plants for spent fuel assemblies, the quantity of plutonium in the waste streams each year is large enough to be important for nuclear safeguards. The wastes are drums of leached hulls and cylinders of vitrified high-level liquid waste. The plutonium amounts in these wastes cannot be measured directly by a nondestructive assay (NDA) technique because the gamma rays emitted by plutonium are obscured by gamma rays from fission products, and the neutrons from spontaneous fissions are obscured by those from curium. The most practical NDA signal from the waste is the neutron emission from curium. A diversion of waste for its plutonium would also take a detectable amount of curium, so if the amount of curium in a waste stream is reduced, it can be inferred that there is also a reduced amount of plutonium. This report studies the feasibility of tracking the curium through a reprocessing plant with neutron measurements at key locations: spent fuel assemblies prior to shearing, the accountability tank after dissolution, drums of leached hulls after dissolution, and canisters of vitrified high-level waste after separation. Existing pertinent measurement techniques are reviewed, improvements are suggested, and new measurements are proposed. The authors integrate these curium measurements into a safeguards system.

  11. 48 CFR 246.370 - Material inspection and receiving report.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... deliverable is a scientific or technical report; (5) Research and development contracts not requiring the... receiving report. 246.370 Section 246.370 Federal Acquisition Regulations System DEFENSE ACQUISITION... Material inspection and receiving report. (a) Use the clause at 252.246-7000, Material Inspection...

  12. 48 CFR 246.370 - Material inspection and receiving report.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... deliverable is a scientific or technical report; (5) Research and development contracts not requiring the... receiving report. 246.370 Section 246.370 Federal Acquisition Regulations System DEFENSE ACQUISITION... Material inspection and receiving report. (a) Use the clause at 252.246-7000, Material Inspection...

  13. 48 CFR 246.370 - Material inspection and receiving report.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... deliverable is a scientific or technical report; (5) Research and development contracts not requiring the... receiving report. 246.370 Section 246.370 Federal Acquisition Regulations System DEFENSE ACQUISITION... Material inspection and receiving report. (a) Use the clause at 252.246-7000, Material Inspection...

  14. 48 CFR 552.246-71 - Source Inspection by Government.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Government. 552.246-71 Section 552.246-71 Federal Acquisition Regulations System GENERAL SERVICES....246-71 Source Inspection by Government. As prescribed in 546.302-71, insert the following clause: Source Inspection by Government (JUNE 1, 2009) (a) Inspection by Government personnel. (1) Supplies to...

  15. 48 CFR 1852.246-73 - Human space flight item.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Human space flight item. 1852.246-73 Section 1852.246-73 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... 1852.246-73 Human space flight item. As prescribed in 1845.370(b), insert the following clause:...

  16. 7 CFR 246.13 - Financial management system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... standard provisions of this part, 7 CFR part 3016, and FNS guidelines and instructions. (e) Identification... 7 Agriculture 4 2010-01-01 2010-01-01 false Financial management system. 246.13 Section 246.13... State Agency Provisions § 246.13 Financial management system. (a) Disclosure of expenditures. The...

  17. 7 CFR 246.13 - Financial management system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... standard provisions of this part, 7 CFR part 3016, and FNS guidelines and instructions. (e) Identification... 7 Agriculture 4 2011-01-01 2011-01-01 false Financial management system. 246.13 Section 246.13... State Agency Provisions § 246.13 Financial management system. (a) Disclosure of expenditures. The...

  18. 7 CFR 246.13 - Financial management system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... standard provisions of this part, 7 CFR part 3016, and FNS guidelines and instructions. (e) Identification... 7 Agriculture 4 2012-01-01 2012-01-01 false Financial management system. 246.13 Section 246.13... State Agency Provisions § 246.13 Financial management system. (a) Disclosure of expenditures. The...

  19. 48 CFR 246.504 - Certificate of conformance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Certificate of conformance. 246.504 Section 246.504 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Acceptance 246.504 Certificate of...

  20. 48 CFR 246.706 - Warranty terms and conditions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Warranty terms and conditions. 246.706 Section 246.706 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.706 Warranty terms...

  1. 7 CFR 246.23 - Claims and penalties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Claims and penalties. 246.23 Section 246.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN Miscellaneous Provisions § 246.23...

  2. 7 CFR 246.23 - Claims and penalties.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Claims and penalties. 246.23 Section 246.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN Miscellaneous Provisions § 246.23...

  3. 25 CFR 900.246 - What does reassumption mean?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What does reassumption mean? 900.246 Section 900.246 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN HEALTH SERVICE, DEPARTMENT OF... Retrocession and Reassumption Procedures § 900.246 What does reassumption mean? Reassumption means...

  4. 25 CFR 900.246 - What does reassumption mean?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What does reassumption mean? 900.246 Section 900.246 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN HEALTH SERVICE, DEPARTMENT OF... Retrocession and Reassumption Procedures § 900.246 What does reassumption mean? Reassumption means...

  5. 25 CFR 900.246 - What does reassumption mean?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What does reassumption mean? 900.246 Section 900.246 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN HEALTH SERVICE, DEPARTMENT OF... Retrocession and Reassumption Procedures § 900.246 What does reassumption mean? Reassumption means...

  6. 29 CFR 1952.246 - Changes to approved plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Changes to approved plans. 1952.246 Section 1952.246 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Alaska § 1952.246 Changes to approved plans. (a) In accordance with...

  7. 48 CFR 246.471 - Authorizing shipment of supplies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Authorizing shipment of supplies. 246.471 Section 246.471 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.471 Authorizing shipment of...

  8. 25 CFR 900.246 - What does reassumption mean?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What does reassumption mean? 900.246 Section 900.246 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN HEALTH SERVICE, DEPARTMENT OF... Retrocession and Reassumption Procedures § 900.246 What does reassumption mean? Reassumption means...

  9. 25 CFR 900.246 - What does reassumption mean?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What does reassumption mean? 900.246 Section 900.246 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND INDIAN HEALTH SERVICE, DEPARTMENT OF... Retrocession and Reassumption Procedures § 900.246 What does reassumption mean? Reassumption means...

  10. 48 CFR 246.371 - Notification of potential safety issues.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... safety issues. 246.371 Section 246.371 Federal Acquisition Regulations System DEFENSE ACQUISITION... Notification of potential safety issues. (a) Use the clause at 252.246-7003, Notification of Potential Safety Issues, in solicitations and contracts for the acquisition of— (1) Repairable or consumable...

  11. 48 CFR 552.246-71 - Source Inspection by Government.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Government. 552.246-71 Section 552.246-71 Federal Acquisition Regulations System GENERAL SERVICES....246-71 Source Inspection by Government. As prescribed in 546.302-71, insert the following clause: Source Inspection by Government (JUNE 1, 2009) (a) Inspection by Government personnel. (1) Supplies to...

  12. 48 CFR 552.246-71 - Source Inspection by Government.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Government. 552.246-71 Section 552.246-71 Federal Acquisition Regulations System GENERAL SERVICES....246-71 Source Inspection by Government. As prescribed in 546.302-71, insert the following clause: Source Inspection by Government (JUN 2009) (a) Inspection by Government personnel. (1) Supplies to...

  13. 48 CFR 246.708 - Warranties of data.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Warranties of data. 246.708 Section 246.708 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.708 Warranties of data....

  14. 48 CFR 246.708 - Warranties of data.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Warranties of data. 246.708 Section 246.708 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.708 Warranties of data....

  15. 48 CFR 1852.246-73 - Human space flight item.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Human space flight item. 1852.246-73 Section 1852.246-73 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... 1852.246-73 Human space flight item. As prescribed in 1845.370(b), insert the following clause:...

  16. 48 CFR 1852.246-73 - Human space flight item.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Human space flight item. 1852.246-73 Section 1852.246-73 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... 1852.246-73 Human space flight item. As prescribed in 1845.370(b), insert the following clause:...

  17. 48 CFR 1852.246-73 - Human space flight item.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Human space flight item. 1852.246-73 Section 1852.246-73 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... 1852.246-73 Human space flight item. As prescribed in 1845.370(b), insert the following clause:...

  18. 7 CFR 246.13 - Financial management system.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... standard provisions of this part, 7 CFR part 3016, and FNS guidelines and instructions. (e) Identification... 7 Agriculture 4 2013-01-01 2013-01-01 false Financial management system. 246.13 Section 246.13... State Agency Provisions § 246.13 Financial management system. (a) Disclosure of expenditures. The...

  19. 48 CFR 1852.246-73 - Human space flight item.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Human space flight item. 1852.246-73 Section 1852.246-73 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... 1852.246-73 Human space flight item. As prescribed in 1845.370(b), insert the following clause:...

  20. 40 CFR 246.202-5 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended procedures: Transportation. 246.202-5 Section 246.202-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.202-5 Recommended procedures: Transportation. Transportation to market may be supplied by...

  1. 40 CFR 246.202-5 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Transportation. 246.202-5 Section 246.202-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.202-5 Recommended procedures: Transportation. Transportation to market may be supplied by...

  2. 40 CFR 246.200-7 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by...

  3. 48 CFR 52.246-14 - Inspection of Transportation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Transportation. 52.246-14 Section 52.246-14 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....246-14 Inspection of Transportation. As prescribed in 46.314, insert the following clause in solicitations and contracts for freight transportation services (including local drayage) by rail,...

  4. 48 CFR 52.246-14 - Inspection of Transportation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Transportation. 52.246-14 Section 52.246-14 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....246-14 Inspection of Transportation. As prescribed in 46.314, insert the following clause in solicitations and contracts for freight transportation services (including local drayage) by rail,...

  5. 40 CFR 246.200-7 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by...

  6. 40 CFR 246.200-7 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by...

  7. 48 CFR 52.246-14 - Inspection of Transportation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Transportation. 52.246-14 Section 52.246-14 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....246-14 Inspection of Transportation. As prescribed in 46.314, insert the following clause in solicitations and contracts for freight transportation services (including local drayage) by rail,...

  8. 40 CFR 246.200-7 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by...

  9. 40 CFR 246.202-5 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Transportation. 246.202-5 Section 246.202-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.202-5 Recommended procedures: Transportation. Transportation to market may be supplied by...

  10. 40 CFR 246.202-5 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Transportation. 246.202-5 Section 246.202-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.202-5 Recommended procedures: Transportation. Transportation to market may be supplied by...

  11. 40 CFR 246.202-5 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Transportation. 246.202-5 Section 246.202-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.202-5 Recommended procedures: Transportation. Transportation to market may be supplied by...

  12. 40 CFR 246.200-7 - Recommended procedures: Transportation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Transportation. 246.200-7 Section 246.200-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 246.200-7 Recommended procedures: Transportation. Transportation to market may be supplied by...

  13. 48 CFR 52.246-14 - Inspection of Transportation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Transportation. 52.246-14 Section 52.246-14 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....246-14 Inspection of Transportation. As prescribed in 46.314, insert the following clause in solicitations and contracts for freight transportation services (including local drayage) by rail,...

  14. Gas-phase energetics of actinide oxides: an assessment of neutral and cationic monoxides and dioxides from thorium to curium.

    PubMed

    Marçalo, Joaquim; Gibson, John K

    2009-11-12

    An assessment of the gas-phase energetics of neutral and singly and doubly charged cationic actinide monoxides and dioxides of thorium, protactinium, uranium, neptunium, plutonium, americium, and curium is presented. A consistent set of metal-oxygen bond dissociation enthalpies, ionization energies, and enthalpies of formation, including new or revised values, is proposed, mainly based on recent experimental data and on correlations with the electronic energetics of the atoms or cations and with condensed-phase thermochemistry. PMID:19725530

  15. Gas-Phase Energetics of Actinide Oxides: An Assessment of Neutral and Cationic Monoxides and Dioxides from Thorium to Curium

    NASA Astrophysics Data System (ADS)

    Marçalo, Joaquim; Gibson, John K.

    2009-09-01

    An assessment of the gas-phase energetics of neutral and singly and doubly charged cationic actinide monoxides and dioxides of thorium, protactinium, uranium, neptunium, plutonium, americium, and curium is presented. A consistent set of metal-oxygen bond dissociation enthalpies, ionization energies, and enthalpies of formation, including new or revised values, is proposed, mainly based on recent experimental data and on correlations with the electronic energetics of the atoms or cations and with condensed-phase thermochemistry.

  16. Gas-phase energies of actinide oxides -- an assessment of neutral and cationic monoxides and dioxides from thorium to curium

    SciTech Connect

    Marcalo, Joaquim; Gibson, John K.

    2009-08-10

    An assessment of the gas-phase energetics of neutral and singly and doubly charged cationic actinide monoxides and dioxides of thorium, protactinium, uranium, neptunium, plutonium, americium, and curium is presented. A consistent set of metal-oxygen bond dissociation enthalpies, ionization energies, and enthalpies of formation, including new or revised values, is proposed, mainly based on recent experimental data and on correlations with the electronic energetics of the atoms or cations and with condensed-phase thermochemistry.

  17. Curium analysis in plutonium uranium mixed oxide by x-ray fluorescence and absorption fine structure spectroscopy.

    PubMed

    Degueldre, C; Borca, C; Cozzo, C

    2013-10-15

    Plutonium uranium mixed oxide (MOX) fuels are being used in commercial nuclear reactors. The actinides in these fuels need to be analyzed after irradiation for assessing their behaviour with regards to their environment and the coolant. In this work the study of the local occurrence, speciation and next-neighbour environment of curium (Cm) in the (Pu,U)O2 lattice within an irradiated (60 MW d kg(-1) average burn-up) MOX sample was performed employing micro-x-ray fluorescence (µ-XRF) and micro-x-ray absorption fine structure (µ-XAFS) spectroscopy. The chemical bonds, valences and stoichiometry of Cm (≈ 0.7 wt% in the rim and ≈ 0.03 wt% in the centre) are determined from the experimental data gained for the irradiated fuel material examined in its centre and peripheral (rim) zones of the fuel. Curium occurrence is also reduced from the centre (hot) to the periphery (colder) because of the condensation of these volatile oxides. In the irradiated sample Cm builds up as Cm(3+) species (>90%) within a [CmO8](13-) or [CmO7](11-) coordination environment and no (<10%) Cm(IV) can be detected in the rim zone. Curium dioxide is reduced because of the redox buffering activity of the uranium dioxide matrix and of its thermodynamic instability. PMID:24054692

  18. Occurrence of earthy and musty odor compounds (geosmin, 2-methylisoborneol and 2,4,6-trichloroanisole) in biologically treated wastewater.

    PubMed

    Urase, T; Sasaki, Y

    2013-01-01

    The concentrations of earthy and musty odor compounds (2-methylisoborneol (2-MIB), geosmin and 2,4,6-trichloroanisole (TCA)) in treated wastewater were measured. Concentrations of 2,4,6-TCA (4.3-37.7 ng/L) and geosmin (3.7-42.2 ng/L) higher than their odor thresholds were detected for effluents from large-scale treatment plants. The effluent from a small-scale wastewater plant treating toilet and kitchen wastewater contained the target earthy and musty odor compounds below the odor thresholds. The ozonation applied as an advanced wastewater treatment process was considerably more effective for the removal of 2,4,6-TCA than for the removal of 2-MIB and geosmin. The measured concentrations of 2,4,6-TCA in river environments without the influence of large-scale wastewater effluents were less than the odor threshold. PMID:24225096

  19. Comparative biokinetics of trivalent radionuclides with similar ionic dimensions: promethium-147, curium-242 and americium-241.

    PubMed

    Priest, N D

    2007-09-01

    Data on the distribution and redistribution patterns in the laboratory rat of three trivalent elements with a similar ionic radius have been compared. This showed that these distributions for the two ions with the same ionic radius (111 pm), i.e., those of promethium (a lanthanoid) and curium (an actinoid), were indistinguishable and that americium, with a slightly larger ion size (111.5 pm), behaved similarly. The results are consistent with the suggestion that ion size is the only important factor controlling the deposition and redistribution patterns of trivalent lanthanoids and actinoids in rats. The result is important because it suggests that the same radiological protection dosimetry models should be used for trivalent actinoids and lanthanoids, that human volunteer data generated for lanthanoid isotopes can be used to predict the behavior of actinoids with the same ion size, and that appropriate pairs of beta-particle-emitting lanthanoid and alpha-particle-emitting actinoids could be used to study the relative toxicity of alpha and beta particles in experimental animals. PMID:17705633

  20. Thermal expansion and self-irradiation damage in curium nitride lattice

    NASA Astrophysics Data System (ADS)

    Takano, Masahide; Hayashi, Hirokazu; Minato, Kazuo

    2014-05-01

    A powder sample of curium nitride (CmN) containing 0.35%-Pu and 3.59%-Am as actinide impurities was prepared by carbothermic nitridation of the oxide. The lattice expansion induced by self-irradiation damage at room temperature was measured as a function of time. The saturated Δa/ao value was 0.43%, which is greater than those for transuranium dioxides available in literature. The undamaged lattice parameter at 297 ± 1 K was determined to be 0.50261 ± 0.00006 nm. Temperature dependence of the lattice parameter was measured by a high temperature X-ray diffractometer in the temperature range up to 1375 K. The linear thermal expansion from 293 to 1273 K was 0.964% and the corresponding thermal expansion coefficient was 9.84 × 10-6 K-1. Comparing with the other actinide nitrides, it was found that CmN lies between the higher expansion nitrides (PuN and AmN) and the lower expansion nitrides (UN and NpN).

  1. The effect of temperature on the sorption of technetium, uranium, neptunium and curium on bentonite, tuff and granodiorite

    SciTech Connect

    Baston, G.M.N.; Berry, J.A.; Brownsword, M.; Heath, T.G.; Ilett, D.J.; Tweed, C.J.; Yui, M.

    1997-12-31

    A study of the sorption of the radioelements technetium; uranium; neptunium; and curium onto geological materials has been carried out as part of the PNC program to increase confidence in the performance assessment for a high-level radioactive waste repository in Japan. Batch sorption experiments have been performed in order to study the sorption of the radioelements onto bentonite, tuff and granodiorite from equilibrated de-ionized water under strongly-reducing conditions at both room temperature and at 60 C. Mathematical modelling using the geochemical speciation program HARPHRQ in conjunction with the HATCHES database has been undertaken in order to interpret the experimental results.

  2. Rapid, quantitative analysis of americium, curium and plutonium isotopes in Hanford samples using extraction chromatography and precipitation plating

    SciTech Connect

    Kaye, J.H.; Strebin, R.S.; Orr, R.D.

    1994-04-01

    Recently developed methods for the rapid, quantitative analysis of americium (Am), curium (Cm), and plutonium (Pu) isotopes in Hanford soil, sludge, and waste-tank samples are described. After dissolution, dilutions are made as necessary based on alpha-energy analysis of a small aliquot of the original solution. isotopic tracers are then added and Am-Cm and Pu are separated by extraction chromatography, coprecipitated with neodymium fluoride, and counted. Examples of alpha spectra are given, and results obtained for Hanford sludge samples are presented.

  3. 48 CFR 852.246-72 - Frozen processed foods.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Frozen processed foods. 852.246-72 Section 852.246-72 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS... Frozen processed foods. As prescribed in 846.302-72, insert the following clause: Frozen Processed...

  4. 21 CFR 520.246 - Butorphanol tartrate tablets.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Butorphanol tartrate tablets. 520.246 Section 520...) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.246 Butorphanol tartrate tablets. (a) Specifications. Each tablet contains 1, 5, or 10 milligrams of butorphanol...

  5. 21 CFR 520.246 - Butorphanol tartrate tablets.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Butorphanol tartrate tablets. 520.246 Section 520...) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.246 Butorphanol tartrate tablets. (a) Specifications. Each tablet contains 1, 5, or 10 milligrams of butorphanol...

  6. 21 CFR 520.246 - Butorphanol tartrate tablets.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Butorphanol tartrate tablets. 520.246 Section 520...) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.246 Butorphanol tartrate tablets. (a) Specifications. Each tablet contains 1, 5, or 10 milligrams of butorphanol...

  7. 21 CFR 520.246 - Butorphanol tartrate tablets.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Butorphanol tartrate tablets. 520.246 Section 520...) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.246 Butorphanol tartrate tablets. (a) Specifications. Each tablet contains 1, 5, or 10 milligrams of butorphanol...

  8. 21 CFR 520.246 - Butorphanol tartrate tablets.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Butorphanol tartrate tablets. 520.246 Section 520...) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.246 Butorphanol tartrate tablets. (a) Specifications. Each tablet contains 1, 5, or 10 milligrams of butorphanol...

  9. 40 CFR 246.200-6 - Recommended procedures: Storage.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....200-6 Section 246.200-6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246..., the use of stationary compactors, or storage in corrugated boxes or normal waste containers....

  10. 48 CFR 852.246-72 - Frozen processed foods.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Frozen processed foods. 852.246-72 Section 852.246-72 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS... Frozen processed foods. As prescribed in 846.302-72, insert the following clause: Frozen Processed...

  11. 48 CFR 852.246-72 - Frozen processed foods.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Frozen processed foods. 852.246-72 Section 852.246-72 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS... Frozen processed foods. As prescribed in 846.302-72, insert the following clause: Frozen Processed...

  12. 48 CFR 852.246-72 - Frozen processed foods.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Frozen processed foods. 852.246-72 Section 852.246-72 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS... Frozen processed foods. As prescribed in 846.302-72, insert the following clause: Frozen Processed...

  13. 48 CFR 852.246-72 - Frozen processed foods.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Frozen processed foods. 852.246-72 Section 852.246-72 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS... Frozen processed foods. As prescribed in 846.302-72, insert the following clause: Frozen Processed...

  14. 32 CFR Appendix A to Part 246 - Mission

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CFR part 212, DoD employees and their immediate families, and others designated by the Unified Command... 32 National Defense 2 2010-07-01 2010-07-01 false Mission A Appendix A to Part 246 National... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. A Appendix A to Part...

  15. 32 CFR Appendix A to Part 246 - Mission

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CFR part 212, DoD employees and their immediate families, and others designated by the Unified Command... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. A Appendix A to Part 246—Mission A. General. The Stars and Strips (S&S) organizations shall contribute to the overall U.S....

  16. 32 CFR Appendix A to Part 246 - Mission

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CFR part 212, DoD employees and their immediate families, and others designated by the Unified Command... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. A Appendix A to Part 246—Mission A. General. The Stars and Strips (S&S) organizations shall contribute to the overall U.S....

  17. 32 CFR Appendix A to Part 246 - Mission

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CFR part 212, DoD employees and their immediate families, and others designated by the Unified Command... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. A Appendix A to Part 246—Mission A. General. The Stars and Strips (S&S) organizations shall contribute to the overall U.S....

  18. 32 CFR Appendix A to Part 246 - Mission

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CFR part 212, DoD employees and their immediate families, and others designated by the Unified Command... STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. A Appendix A to Part 246—Mission A. General. The Stars and Strips (S&S) organizations shall contribute to the overall U.S....

  19. 7 CFR 246.13 - Financial management system.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Financial management system. 246.13 Section 246.13 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN State Agency Provisions §...

  20. 7 CFR 246.19 - Management evaluation and monitoring reviews.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Management evaluation and monitoring reviews. 246.19... WOMEN, INFANTS AND CHILDREN Monitoring and Review § 246.19 Management evaluation and monitoring reviews. (a) Management evaluations and reviews. (1) FNS and each State agency shall establish a...

  1. 7 CFR 246.22 - Administrative appeal of FNS decisions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture, Food and Nutrition Service, 3101 Park Center Drive, Alexandria, Va. 22302, for a hearing or a... 7 Agriculture 4 2011-01-01 2011-01-01 false Administrative appeal of FNS decisions. 246.22 Section 246.22 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION...

  2. 7 CFR 246.22 - Administrative appeal of FNS decisions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Agriculture, Food and Nutrition Service, 3101 Park Center Drive, Alexandria, Va. 22302, for a hearing or a... 7 Agriculture 4 2013-01-01 2013-01-01 false Administrative appeal of FNS decisions. 246.22 Section 246.22 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION...

  3. 7 CFR 246.22 - Administrative appeal of FNS decisions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture, Food and Nutrition Service, 3101 Park Center Drive, Alexandria, Va. 22302, for a hearing or a... 7 Agriculture 4 2010-01-01 2010-01-01 false Administrative appeal of FNS decisions. 246.22 Section 246.22 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION...

  4. 7 CFR 246.22 - Administrative appeal of FNS decisions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Agriculture, Food and Nutrition Service, 3101 Park Center Drive, Alexandria, Va. 22302, for a hearing or a... 7 Agriculture 4 2014-01-01 2014-01-01 false Administrative appeal of FNS decisions. 246.22 Section 246.22 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION...

  5. 7 CFR 246.22 - Administrative appeal of FNS decisions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Agriculture, Food and Nutrition Service, 3101 Park Center Drive, Alexandria, Va. 22302, for a hearing or a... 7 Agriculture 4 2012-01-01 2012-01-01 false Administrative appeal of FNS decisions. 246.22 Section 246.22 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION...

  6. Toxicological profile for 2,4,6-trinitrotoluene

    SciTech Connect

    1995-11-01

    This Statement was prepared to give you information about 2,4,6-trinitrotoluene and to emphasize the human health effects that may result from exposure to it. The Environmental Protection Agency (EPA) has identified 1,397 sites on its National Priorities List (NPL). 2,4,6-Trinitrotoluene has been found in at least 20 of these sites.

  7. 7 CFR 246.6 - Agreements with local agencies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Agreements with local agencies. 246.6 Section 246.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN State and Local...

  8. 7 CFR 246.16a - Infant formula cost containment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Infant formula cost containment. 246.16a Section 246.16a Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN State Agency Provisions...

  9. 7 CFR 246.6 - Agreements with local agencies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Agreements with local agencies. 246.6 Section 246.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN State and Local...

  10. 7 CFR 246.16a - Infant formula cost containment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Infant formula cost containment. 246.16a Section 246.16a Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN State Agency Provisions...

  11. 7 CFR 246.5 - Selection of local agencies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Selection of local agencies. 246.5 Section 246.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN State and Local Agency Eligibility...

  12. 7 CFR 246.6 - Agreements with local agencies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Agreements with local agencies. 246.6 Section 246.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN State and Local...

  13. 7 CFR 246.5 - Selection of local agencies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Selection of local agencies. 246.5 Section 246.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN State and Local Agency Eligibility...

  14. 48 CFR 246.407 - Nonconforming supplies or services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Nonconforming supplies or services. 246.407 Section 246.407 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality...

  15. 7 CFR 246.24 - Procurement and property management.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... to the standards set forth in A-130 and 7 CFR part 3016. (d) Property acquired with Program funds... 7 Agriculture 4 2014-01-01 2014-01-01 false Procurement and property management. 246.24 Section... AND CHILDREN Miscellaneous Provisions § 246.24 Procurement and property management. (a)...

  16. 7 CFR 246.24 - Procurement and property management.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... to the standards set forth in A-130 and 7 CFR part 3016. (d) Property acquired with Program funds... 7 Agriculture 4 2012-01-01 2012-01-01 false Procurement and property management. 246.24 Section... AND CHILDREN Miscellaneous Provisions § 246.24 Procurement and property management. (a)...

  17. 7 CFR 246.24 - Procurement and property management.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... to the standards set forth in A-130 and 7 CFR part 3016. (d) Property acquired with Program funds... 7 Agriculture 4 2011-01-01 2011-01-01 false Procurement and property management. 246.24 Section... AND CHILDREN Miscellaneous Provisions § 246.24 Procurement and property management. (a)...

  18. 7 CFR 246.24 - Procurement and property management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... to the standards set forth in A-130 and 7 CFR part 3016. (d) Property acquired with Program funds... 7 Agriculture 4 2010-01-01 2010-01-01 false Procurement and property management. 246.24 Section... AND CHILDREN Miscellaneous Provisions § 246.24 Procurement and property management. (a)...

  19. 7 CFR 246.24 - Procurement and property management.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... to the standards set forth in A-130 and 7 CFR part 3016. (d) Property acquired with Program funds... 7 Agriculture 4 2013-01-01 2013-01-01 false Procurement and property management. 246.24 Section... AND CHILDREN Miscellaneous Provisions § 246.24 Procurement and property management. (a)...

  20. 12 CFR 303.246 - Conversion with diminution of capital.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... description of the proposed transaction; (2) A schedule detailing the present and proposed capital structure... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Conversion with diminution of capital. 303.246... FILING PROCEDURES Other Filings § 303.246 Conversion with diminution of capital. (a) Scope. This...

  1. 12 CFR 303.246 - Conversion with diminution of capital.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... description of the proposed transaction; (2) A schedule detailing the present and proposed capital structure... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Conversion with diminution of capital. 303.246... FILING PROCEDURES Other Filings § 303.246 Conversion with diminution of capital. (a) Scope. This...

  2. 48 CFR 246.370 - Material inspection and receiving report.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Material inspection and receiving report. 246.370 Section 246.370 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses...

  3. 48 CFR 246.370 - Material inspection and receiving report.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Material inspection and receiving report. 246.370 Section 246.370 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses...

  4. 48 CFR 246.408 - Single-agency assignments of Government contract quality assurance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of Government contract quality assurance. 246.408 Section 246.408 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.408 Single-agency assignments of Government...

  5. 42 CFR 24.6 - Pay and compensation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... RESEARCH SERVICE § 24.6 Pay and compensation. The SBRS is an ungraded system, with a single, flexible pay... scientist. (d) The following factors will be used in establishing appropriate pay rates for...

  6. 42 CFR 24.6 - Pay and compensation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... RESEARCH SERVICE § 24.6 Pay and compensation. The SBRS is an ungraded system, with a single, flexible pay... scientist. (d) The following factors will be used in establishing appropriate pay rates for...

  7. 48 CFR 246.103 - Contracting office responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE General 246.103 Contracting office responsibilities. (1) The contracting office must coordinate with the quality assurance activity before changing any quality requirement. (2) The activity responsible for technical requirements may...

  8. 48 CFR 246.202 - Types of contract quality requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 246.202 Types of contract quality requirements. ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Types of contract...

  9. 42 CFR 24.6 - Pay and compensation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... RESEARCH SERVICE § 24.6 Pay and compensation. The SBRS is an ungraded system, with a single, flexible pay... scientist. (d) The following factors will be used in establishing appropriate pay rates for...

  10. 42 CFR 24.6 - Pay and compensation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... RESEARCH SERVICE § 24.6 Pay and compensation. The SBRS is an ungraded system, with a single, flexible pay... scientist. (d) The following factors will be used in establishing appropriate pay rates for...

  11. 42 CFR 24.6 - Pay and compensation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... RESEARCH SERVICE § 24.6 Pay and compensation. The SBRS is an ungraded system, with a single, flexible pay... scientist. (d) The following factors will be used in establishing appropriate pay rates for...

  12. 48 CFR 246.704 - Authority for use of warranties.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... acquisitions for— (i) Commercial items (see FAR 46.709); (ii) Technical data, unless the warranty provides for extended liability (see 246.708); (iii) Supplies and services in fixed-price type contracts...

  13. 48 CFR 246.710 - Solicitation provision and contract clauses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.710... clause at 252.227-7013, Rights in Technical Data and Computer Software, when there is a need for...

  14. 48 CFR 246.710 - Solicitation provision and contract clauses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.710... in Technical Data and Computer Software, when there is a need for greater protection or period...

  15. 48 CFR 246.710 - Solicitation provision and contract clauses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.710... in Technical Data and Computer Software, when there is a need for greater protection or period...

  16. Atomic Mass and Nuclear Binding Energy for Pa-246 (Protactinium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Pa-246 (Protactinium, atomic number Z = 91, mass number A = 246).

  17. Atomic Mass and Nuclear Binding Energy for Es-246 (Einsteinium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Es-246 (Einsteinium, atomic number Z = 99, mass number A = 246).

  18. Atomic Mass and Nuclear Binding Energy for At-246 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-246 (Astatine, atomic number Z = 85, mass number A = 246).

  19. Atomic Mass and Nuclear Binding Energy for Ac-246 (Actinium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Ac-246 (Actinium, atomic number Z = 89, mass number A = 246).

  20. 48 CFR 2152.246-70 - Quality assurance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Quality assurance... MANAGEMENT, FEDERAL EMPLOYEES GROUP LIFE INSURANCE FEDERAL ACQUISITION REGULATION CLAUSES AND FORMS PRECONTRACT PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 2152.246-70 Quality...

  1. 48 CFR 2452.246-70 - Inspection and acceptance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Inspection and acceptance... 2452.246-70 Inspection and acceptance. As prescribed in 2446.502-70, insert the following clause in all solicitations and contracts: Inspection and Acceptance (FEB 2006) Inspection and acceptance of all work...

  2. 48 CFR 2452.246-70 - Inspection and acceptance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Inspection and acceptance... 2452.246-70 Inspection and acceptance. As prescribed in 2446.502-70, insert the following clause in all solicitations and contracts: Inspection and Acceptance (FEB 2006) Inspection and acceptance of all work...

  3. 40 CFR 86.246-94 - Intermediate temperature testing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) contained in 40 CFR part 86, subpart C. (c) For testing at temperatures of 50 °F (10 °C) or higher, the FTP... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Intermediate temperature testing. 86... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.246-94...

  4. 40 CFR 421.246 - Pretreatment standards for new sources.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... § 421.246 Pretreatment standards for new sources. Except as provided in 40 CFR 403.7, any new source... 40 CFR part 403 and achieve the following pretreatment standards for new sources. The mass of... following values: (a) Slag reclaim tailings. PSNS for the Secondary Nickel Subcategory Pollutant...

  5. 40 CFR 421.246 - Pretreatment standards for new sources.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... § 421.246 Pretreatment standards for new sources. Except as provided in 40 CFR 403.7, any new source... 40 CFR part 403 and achieve the following pretreatment standards for new sources. The mass of... following values: (a) Slag reclaim tailings. PSNS for the Secondary Nickel Subcategory Pollutant...

  6. 40 CFR 421.246 - Pretreatment standards for new sources.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... § 421.246 Pretreatment standards for new sources. Except as provided in 40 CFR 403.7, any new source... 40 CFR part 403 and achieve the following pretreatment standards for new sources. The mass of... following values: (a) Slag reclaim tailings. PSNS for the Secondary Nickel Subcategory Pollutant...

  7. 40 CFR 421.246 - Pretreatment standards for new sources.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... § 421.246 Pretreatment standards for new sources. Except as provided in 40 CFR 403.7, any new source... 40 CFR part 403 and achieve the following pretreatment standards for new sources. The mass of... following values: (a) Slag reclaim tailings. PSNS for the Secondary Nickel Subcategory Pollutant...

  8. 7 CFR 246.25 - Records and reports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... with 7 CFR part 3016 and the following requirements: (1) Records shall include, but not be limited to..., equipment purchases and inventory, certification, nutrition education, including breastfeeding promotion and... reports, as required by § 246.17(b)(2). (iii) The State agency must submit local agency...

  9. 7 CFR 246.25 - Records and reports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... with 7 CFR part 3016 and the following requirements: (1) Records shall include, but not be limited to..., equipment purchases and inventory, certification, nutrition education, including breastfeeding promotion and... reports, as required by § 246.17(b)(2). (iii) The State agency must submit local agency...

  10. 7 CFR 246.25 - Records and reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... with 7 CFR part 3016 and the following requirements: (1) Records shall include, but not be limited to..., equipment purchases and inventory, certification, nutrition education, including breastfeeding promotion and... reports, as required by § 246.17(b)(2). (iii) The State agency must submit local agency...

  11. 7 CFR 246.12 - Food delivery systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... property, making false claims, and obstruction of justice. The State agency may add other types of... agency or its local agencies. (xx) Criminal penalties. A vendor who commits fraud or abuse in the Program... 7 Agriculture 4 2010-01-01 2010-01-01 false Food delivery systems. 246.12 Section...

  12. 7 CFR 246.12 - Food delivery systems.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... property, making false claims, and obstruction of justice. The State agency may add other types of... agency or its local agencies. (xx) Criminal penalties. A vendor who commits fraud or abuse in the Program... 7 Agriculture 4 2011-01-01 2011-01-01 false Food delivery systems. 246.12 Section...

  13. 7 CFR 246.12 - Food delivery systems.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., receiving stolen property, making false claims, and obstruction of justice. The State agency may add other... agency or its local agencies. (xx) Criminal penalties. A vendor who commits fraud or abuse in the Program... 7 Agriculture 4 2012-01-01 2012-01-01 false Food delivery systems. 246.12 Section...

  14. 7 CFR 246.12 - Food delivery systems.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., receiving stolen property, making false claims, and obstruction of justice. The State agency may add other... agency or its local agencies. (xx) Criminal penalties. A vendor who commits fraud or abuse in the Program... 7 Agriculture 4 2013-01-01 2013-01-01 false Food delivery systems. 246.12 Section...

  15. 7 CFR 246.12 - Food delivery systems.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., receiving stolen property, making false claims, and obstruction of justice. The State agency may add other... agency or its local agencies. (xx) Criminal penalties. A vendor who commits fraud or abuse in the Program... 7 Agriculture 4 2014-01-01 2014-01-01 false Food delivery systems. 246.12 Section...

  16. 48 CFR 2152.246-70 - Quality assurance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Quality assurance... PRECONTRACT PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 2152.246-70 Quality assurance requirements. As prescribed by 2146.270-1 insert the following clause: Quality Assurance Requirements (OCT...

  17. 48 CFR 246.470-2 - Quality evaluation data.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Quality evaluation data... SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.470-2 Quality evaluation data. The contract administration office shall establish a system for...

  18. 40 CFR 246.202-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...: (a) Identifying potential purchasers of the recovered corrugated through standard market research... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Market study... § 246.202-3 Recommended procedures: Market study. An investigation of markets should be made by...

  19. 40 CFR 246.201-4 - Recommended procedures: Market study.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Market study... § 246.201-4 Recommended procedures: Market study. An investigation of markets should be made for each... at a minimum: (a) Identifying potential purchasers of the recovered material through standard...

  20. 40 CFR 246.200-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... minimum: (a) Identifying potential purchasers of the recovered paper through standard market research... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Market study... § 246.200-3 Recommended procedures: Market study. An investigation of markets should be made by...

  1. 29 CFR 1952.246 - Changes to approved plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (29 CFR 1928.110) and temporary labor camps (29 CFR 1910.142) in agriculture (except for agricultural... (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Alaska § 1952.246 Changes to approved... by the Assistant Secretary: (1) The State submitted a revised field operations manual patterned...

  2. 29 CFR 1952.246 - Changes to approved plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (29 CFR 1928.110) and temporary labor camps (29 CFR 1910.142) in agriculture (except for agricultural... (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Alaska § 1952.246 Changes to approved... by the Assistant Secretary: (1) The State submitted a revised field operations manual patterned...

  3. 29 CFR 1952.246 - Changes to approved plans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (29 CFR 1928.110) and temporary labor camps (29 CFR 1910.142) in agriculture (except for agricultural... (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Alaska § 1952.246 Changes to approved... by the Assistant Secretary: (1) The State submitted a revised field operations manual patterned...

  4. 48 CFR 246.470-2 - Quality evaluation data.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.470-2 Quality evaluation data. The contract administration office shall establish a system for the... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Quality evaluation...

  5. 2,4,6-TRINITROTOLUENE TRANSFORMATION IN PLANTED, SOIL COLUMNS

    EPA Science Inventory

    2,4,6-Trinitrotoluene (TNT), has been used extensively by the United States military to manufacture explosive devices. Since the conclusion of World War 11, many of these military installations have also been involved in the disposal of surplus and outdated explosives. Both the c...

  6. 40 CFR 86.246-94 - Intermediate temperature testing.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) contained in 40 CFR part 86, subpart C. (c) For testing at temperatures of 50 °F (10 °C) or higher, the FTP... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Intermediate temperature testing. 86... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.246-94...

  7. 40 CFR 86.246-94 - Intermediate temperature testing.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) contained in 40 CFR part 86, subpart C. (c) For testing at temperatures of 50 °F (10 °C) or higher, the FTP... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Intermediate temperature testing. 86... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.246-94...

  8. 40 CFR 86.246-94 - Intermediate temperature testing.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) contained in 40 CFR part 86, subpart C. (c) For testing at temperatures of 50 °F (10 °C) or higher, the FTP... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Intermediate temperature testing. 86... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.246-94...

  9. 29 CFR 1952.246 - Changes to approved plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (29 CFR 1928.110) and temporary labor camps (29 CFR 1910.142) in agriculture (except for agricultural... (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Alaska § 1952.246 Changes to approved... by the Assistant Secretary: (1) The State submitted a revised field operations manual patterned...

  10. 40 CFR 246.201-4 - Recommended procedures: Market study.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Market study... § 246.201-4 Recommended procedures: Market study. An investigation of markets should be made for each... at a minimum: (a) Identifying potential purchasers of the recovered material through standard...

  11. 40 CFR 246.202-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Market study... § 246.202-3 Recommended procedures: Market study. An investigation of markets should be made by the...: (a) Identifying potential purchasers of the recovered corrugated through standard market...

  12. 40 CFR 246.200-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Market study... § 246.200-3 Recommended procedures: Market study. An investigation of markets should be made by the... minimum: (a) Identifying potential purchasers of the recovered paper through standard market...

  13. 40 CFR 246.201-4 - Recommended procedures: Market study.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended procedures: Market study... § 246.201-4 Recommended procedures: Market study. An investigation of markets should be made for each... at a minimum: (a) Identifying potential purchasers of the recovered material through standard...

  14. 40 CFR 246.200-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Market study... § 246.200-3 Recommended procedures: Market study. An investigation of markets should be made by the... minimum: (a) Identifying potential purchasers of the recovered paper through standard market...

  15. 40 CFR 246.202-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Market study... § 246.202-3 Recommended procedures: Market study. An investigation of markets should be made by the...: (a) Identifying potential purchasers of the recovered corrugated through standard market...

  16. 40 CFR 246.201-4 - Recommended procedures: Market study.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Market study... § 246.201-4 Recommended procedures: Market study. An investigation of markets should be made for each... at a minimum: (a) Identifying potential purchasers of the recovered material through standard...

  17. 40 CFR 246.202-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Market study... § 246.202-3 Recommended procedures: Market study. An investigation of markets should be made by the...: (a) Identifying potential purchasers of the recovered corrugated through standard market...

  18. 40 CFR 246.201-4 - Recommended procedures: Market study.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Market study... § 246.201-4 Recommended procedures: Market study. An investigation of markets should be made for each... at a minimum: (a) Identifying potential purchasers of the recovered material through standard...

  19. 40 CFR 246.200-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Market study... § 246.200-3 Recommended procedures: Market study. An investigation of markets should be made by the... minimum: (a) Identifying potential purchasers of the recovered paper through standard market...

  20. 40 CFR 246.200-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended procedures: Market study... § 246.200-3 Recommended procedures: Market study. An investigation of markets should be made by the... minimum: (a) Identifying potential purchasers of the recovered paper through standard market...

  1. 40 CFR 246.202-3 - Recommended procedures: Market study.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended procedures: Market study... § 246.202-3 Recommended procedures: Market study. An investigation of markets should be made by the...: (a) Identifying potential purchasers of the recovered corrugated through standard market...

  2. 48 CFR 52.246-21 - Warranty of Construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Warranty of Construction....246-21 Warranty of Construction. As prescribed in 46.710(e)(1), the contracting officer may insert a clause substantially as follows in solicitations and contracts when a fixed-price construction...

  3. 48 CFR 52.246-12 - Inspection of Construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Inspection of Construction....246-12 Inspection of Construction. As prescribed in 46.312, insert the following clause: Inspection of Construction (AUG 1996) (a) Definition. Work includes, but is not limited to, materials, workmanship,...

  4. 27 CFR 28.246 - Delivery for shipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Delivery for shipment. 28..., DEPARTMENT OF THE TREASURY LIQUORS EXPORTATION OF ALCOHOL Shipment or Delivery for Export Consignment § 28.246 Delivery for shipment. The proprietor or exporter may deliver the shipment directly to...

  5. 48 CFR 246.471 - Authorizing shipment of supplies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... required by the contract; 2. Were shipped in accordance with authorized shipping instructions; 3. Conform... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Authorizing shipment of... 246.471 Authorizing shipment of supplies. (a) General. (1) Ordinarily, a representative of...

  6. 40 CFR 421.246 - Pretreatment standards for new sources.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Secondary Nickel Subcategory § 421.246 Pretreatment standards for new sources. Except as provided in 40 CFR 403.7, any new source... 40 CFR part 403 and achieve the following pretreatment standards for new sources. The mass...

  7. 48 CFR 552.246-71 - Source Inspection by Government.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Source Inspection by....246-71 Source Inspection by Government. As prescribed in 546.302-71, insert the following clause: Source Inspection by Government (JUNE 1, 2009) (a) Inspection by Government personnel. (1) Supplies to...

  8. Chemical Speciation of Strontium, Americium, and Curium in High Level Waste: Predictive Modeling of Phase Partitioning During Tank Processing

    SciTech Connect

    Felmy, Andrew R.; Choppin, Gregory; Dixon, David A.; Campbell, James A.

    1999-06-01

    In this research program, Pacific Northwest National Laboratory (PNNL) and Florida State University (FSU) are investigating the speciation of strontium and americium/curium in the presence of selected organic chelating agents (ethylenediaminetetraacetic acid (EDTA), N-(2-hydroxyethyl) aethylenediaminetriacetic acid (HEDTA), nitrilotriacetic acid (NTA), and iminodiacetic acid (IDA)) over ranges of hydroxide, carbonate, ionic strength, and competing metal ion concentrations present in high-level waste tanks. The project is composed of integrated research tasks that approach the problem of chemical speciation using macroscopic thermodynamic measurements of metal-ligand competition reactions, molecular modeling studies to identify structures or complexes of unusual stability, and mass spectrometry measurements of complex charge/mass ratio that can be applied to mixed metal-chelate systems. This fundamental information is then used to develop thermodynamic models, which allow the prediction of changes in chemical speciation and solubility that can occur in response to changes in tank processing conditions. In this way, we can develop new approaches that address fundamental problems in aqueous speciation and at the same time provide useful and practical information needed for tank processing.

  9. Bioanalysis of uranium, plutonium, and curium on breathing zone air samples by solvent extraction and PERALS spectroscopy

    SciTech Connect

    Metzger, R.L.; Jessop, B.H.; McDowell, B.L.

    1995-12-31

    Breathing zone air samples are commonly used to monitor airborne concentrate of radionuclides in ions the workplace and to assess the efficacy of respiratory protection programs. Radioactive isotopes of actinides have very low allowable airborne concentrations, so knowledge of the airborne activities of these nuclides is crucial. The air samples are typically analyzed for alpha-particle-emitting radionuclides by direct counting of the filters or by conventional separation chemistry and alpha-particle spectrometry. These techniques do not normally provide a sample turnaround that is sufficiently rapid to allow a change in the respiratory protection program, if necessary. In this work we have developed straightforward solvent extraction separation procedures that can rapidly phase transfer isotopes of uranium, plutonium, and americium or curium from a dissolved filter medium to an extractive scintillator for counting on a Photon/Electron-Rejecting Alpha Liquid Scintillation (PERALS{sup {reg_sign}}) Spectrometer. Results can normally be obtained within eight hours from the receipt of the air filter.

  10. Actinide Production in the Reaction of Heavy Ions withCurium-248

    SciTech Connect

    Moody, K.J.

    1983-07-01

    Chemical experiments were performed to examine the usefulness of heavy ion transfer reactions in producing new, neutron-rich actinide nuclides. A general quasi-elastic to deep-inelastic mechanism is proposed, and the utility of this method as opposed to other methods (e.g. complete fusion) is discussed. The relative merits of various techniques of actinide target synthesis are discussed. A description is given of a target system designed to remove the large amounts of heat generated by the passage of a heavy ion beam through matter, thereby maximizing the beam intensity which can be safely used in an experiment. Also described is a general separation scheme for the actinide elements from protactinium (Z = 91) to mendelevium (Z = 101), and fast specific procedures for plutonium, americium and berkelium. The cross sections for the production of several nuclides from the bombardment of {sup 248}Cm with {sup 18}O, {sup 86}Kr and {sup 136}Xe projectiles at several energies near and below the Coulomb barrier were determined. The results are compared with yields from {sup 48}Ca and {sup 238}U bombardments of {sup 248}Cm. Simple extrapolation of the product yields into unknown regions of charge and mass indicates that the use of heavy ion transfer reactions to produce new, neutron-rich above-target species is limited. The substantial production of neutron-rich below-target species, however, indicates that with very heavy ions like {sup 136}Xe and {sup 238}U the new species {sup 248}Am, {sup 249}Am and {sup 247}Pu should be produced with large cross sections from a {sup 248}Cm target. A preliminary, unsuccessful attempt to isolate {sup 247}Pu is outlined. The failure is probably due to the half life of the decay, which is calculated to be less than 3 minutes. The absolute gamma ray intensities from {sup 251}Bk decay, necessary for calculating the {sup 251}Bk cross section, are also determined.

  11. 30 CFR 550.246 - What mineral resource conservation information must accompany the DPP or DOCD?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What mineral resource conservation information must accompany the DPP or DOCD? 550.246 Section 550.246 Mineral Resources BUREAU OF OCEAN ENERGY... Operations Coordination Documents (docd) § 550.246 What mineral resource conservation information...

  12. 30 CFR 550.246 - What mineral resource conservation information must accompany the DPP or DOCD?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What mineral resource conservation information must accompany the DPP or DOCD? 550.246 Section 550.246 Mineral Resources BUREAU OF OCEAN ENERGY... Operations Coordination Documents (docd) § 550.246 What mineral resource conservation information...

  13. 30 CFR 550.246 - What mineral resource conservation information must accompany the DPP or DOCD?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What mineral resource conservation information must accompany the DPP or DOCD? 550.246 Section 550.246 Mineral Resources BUREAU OF OCEAN ENERGY... Operations Coordination Documents (docd) § 550.246 What mineral resource conservation information...

  14. 40 CFR 246.202-4 - Recommended procedures: Methods of separation and storage.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... separation and storage. 246.202-4 Section 246.202-4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.202-4 Recommended procedures: Methods of separation and storage. The method selected...

  15. 40 CFR 246.201-5 - Recommended procedures: Methods of separation and collection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... separation and collection. 246.201-5 Section 246.201-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.201-5 Recommended procedures: Methods of separation and collection....

  16. 40 CFR 246.201-6 - Recommended procedures: Transportation to market.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Transportation to market. 246.201-6 Section 246.201-6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Procedures § 246.201-6 Recommended procedures: Transportation to market. Transportation to market may...

  17. 40 CFR 246.201-9 - Recommended procedures: Public information and education.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... information and education. 246.201-9 Section 246.201-9 Protection of Environment ENVIRONMENTAL PROTECTION... Recommended Procedures § 246.201-9 Recommended procedures: Public information and education. A well organized and well executed public information and education program explaining the justification,...

  18. 40 CFR 246.200-10 - Recommended procedures: Public information and education.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... information and education. 246.200-10 Section 246.200-10 Protection of Environment ENVIRONMENTAL PROTECTION... Recommended Procedures § 246.200-10 Recommended procedures: Public information and education. A well-organized and well-executed public information and education program explaining the justification,...

  19. 7 CFR 58.246 - Cleaning of dryers, collectors, conveyors, ducts, sifters and storage bins.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Cleaning of dryers, collectors, conveyors, ducts, sifters and storage bins. 58.246 Section 58.246 Agriculture Regulations of the Department of Agriculture... Inspection and Grading Service 1 Operations and Operating Procedures § 58.246 Cleaning of dryers,...

  20. 7 CFR 58.246 - Cleaning of dryers, collectors, conveyors, ducts, sifters and storage bins.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Cleaning of dryers, collectors, conveyors, ducts, sifters and storage bins. 58.246 Section 58.246 Agriculture Regulations of the Department of Agriculture... Inspection and Grading Service 1 Operations and Operating Procedures § 58.246 Cleaning of dryers,...

  1. 7 CFR 58.246 - Cleaning of dryers, collectors, conveyors, ducts, sifters and storage bins.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Cleaning of dryers, collectors, conveyors, ducts, sifters and storage bins. 58.246 Section 58.246 Agriculture Regulations of the Department of Agriculture... Inspection and Grading Service 1 Operations and Operating Procedures § 58.246 Cleaning of dryers,...

  2. 7 CFR 58.246 - Cleaning of dryers, collectors, conveyors, ducts, sifters and storage bins.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Cleaning of dryers, collectors, conveyors, ducts, sifters and storage bins. 58.246 Section 58.246 Agriculture Regulations of the Department of Agriculture... Inspection and Grading Service 1 Operations and Operating Procedures § 58.246 Cleaning of dryers,...

  3. 30 CFR 250.246 - What mineral resource conservation information must accompany the DPP or DOCD?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What mineral resource conservation information must accompany the DPP or DOCD? 250.246 Section 250.246 Mineral Resources MINERALS MANAGEMENT SERVICE... Coordination Documents (docd) § 250.246 What mineral resource conservation information must accompany the...

  4. 48 CFR 52.246-8 - Inspection of Research and Development-Cost-Reimbursement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Development-Cost-Reimbursement. 52.246-8 Section 52.246-8 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.246-8 Inspection of Research and Development—Cost-Reimbursement. As prescribed in 46.308, insert the following clause in solicitations and contracts for research and development...

  5. 40 CFR 246.200-4 - Recommended procedures: Levels of separation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... separation. 246.200-4 Section 246.200-4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.200-4 Recommended procedures: Levels of separation. A two-level separation is recommended for...

  6. 40 CFR 246.202-4 - Recommended procedures: Methods of separation and storage.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... separation and storage. 246.202-4 Section 246.202-4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.202-4 Recommended procedures: Methods of separation and storage. The method selected...

  7. 40 CFR 246.200-4 - Recommended procedures: Levels of separation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... separation. 246.200-4 Section 246.200-4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.200-4 Recommended procedures: Levels of separation. A two-level separation is recommended for...

  8. 40 CFR 246.202-4 - Recommended procedures: Methods of separation and storage.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... separation and storage. 246.202-4 Section 246.202-4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.202-4 Recommended procedures: Methods of separation and storage. The method selected...

  9. 40 CFR 246.200-4 - Recommended procedures: Levels of separation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... separation. 246.200-4 Section 246.200-4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.200-4 Recommended procedures: Levels of separation. A two-level separation is recommended for...

  10. 40 CFR 246.200-4 - Recommended procedures: Levels of separation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... separation. 246.200-4 Section 246.200-4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.200-4 Recommended procedures: Levels of separation. A two-level separation is recommended for...

  11. 40 CFR 246.201-5 - Recommended procedures: Methods of separation and collection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... separation and collection. 246.201-5 Section 246.201-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.201-5 Recommended procedures: Methods of separation and collection....

  12. 40 CFR 246.201-5 - Recommended procedures: Methods of separation and collection.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... separation and collection. 246.201-5 Section 246.201-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.201-5 Recommended procedures: Methods of separation and collection....

  13. 48 CFR 552.246-77 - Additional Contract Warranty Provisions for Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Warranty Provisions for Supplies of a Noncomplex Nature. 552.246-77 Section 552.246-77 Federal Acquisition... a Noncomplex Nature. As prescribed in 546.710(a), insert the following clause in solicitations and contracts that include FAR 52.246-17, Warranty of Supplies of a Noncomplex Nature. Additional...

  14. 48 CFR 52.246-17 - Warranty of Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Noncomplex Nature. 52.246-17 Section 52.246-17 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-17 Warranty of Supplies of a Noncomplex Nature. As prescribed in 46.710(a)(1), insert a clause substantially as follows: Warranty of Supplies of a Noncomplex Nature (JUN 2003) (a)...

  15. 48 CFR 52.246-18 - Warranty of Supplies of a Complex Nature.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Complex Nature. 52.246-18 Section 52.246-18 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-18 Warranty of Supplies of a Complex Nature. As prescribed in 46.710(b)(1), insert a clause substantially as follows: Warranty of Supplies of a Complex Nature (MAY 2001) (a) Definitions. As used in...

  16. 48 CFR 246.402 - Government contract quality assurance at source.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... quality assurance at source. 246.402 Section 246.402 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.402 Government contract quality assurance at source. Do not...

  17. 48 CFR 246.202-4 - Higher-level contract quality requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... quality requirements. 246.202-4 Section 246.202-4 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 246.202-4 Higher-level contract quality requirements. (1) Higher-level contract...

  18. 48 CFR 552.246-77 - Additional Contract Warranty Provisions for Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Warranty Provisions for Supplies of a Noncomplex Nature. 552.246-77 Section 552.246-77 Federal Acquisition... a Noncomplex Nature. As prescribed in 546.710(a), insert the following clause in solicitations and contracts that include FAR 52.246-17, Warranty of Supplies of a Noncomplex Nature. Additional...

  19. 48 CFR 52.246-17 - Warranty of Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Noncomplex Nature. 52.246-17 Section 52.246-17 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-17 Warranty of Supplies of a Noncomplex Nature. As prescribed in 46.710(a)(1), insert a clause substantially as follows: Warranty of Supplies of a Noncomplex Nature (JUN 2003) (a)...

  20. 48 CFR 52.246-17 - Warranty of Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Noncomplex Nature. 52.246-17 Section 52.246-17 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-17 Warranty of Supplies of a Noncomplex Nature. As prescribed in 46.710(a)(1), insert a clause substantially as follows: Warranty of Supplies of a Noncomplex Nature (JUN 2003) (a)...

  1. 48 CFR 52.246-18 - Warranty of Supplies of a Complex Nature.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Complex Nature. 52.246-18 Section 52.246-18 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-18 Warranty of Supplies of a Complex Nature. As prescribed in 46.710(b)(1), insert a clause substantially as follows: Warranty of Supplies of a Complex Nature (MAY 2001) (a) Definitions. As used in...

  2. 48 CFR 52.246-17 - Warranty of Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Noncomplex Nature. 52.246-17 Section 52.246-17 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-17 Warranty of Supplies of a Noncomplex Nature. As prescribed in 46.710(a)(1), insert a clause substantially as follows: Warranty of Supplies of a Noncomplex Nature (JUN 2003) (a)...

  3. 48 CFR 52.246-18 - Warranty of Supplies of a Complex Nature.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Complex Nature. 52.246-18 Section 52.246-18 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-18 Warranty of Supplies of a Complex Nature. As prescribed in 46.710(b)(1), insert a clause substantially as follows: Warranty of Supplies of a Complex Nature (MAY 2001) (a) Definitions. As used in...

  4. 48 CFR 552.246-77 - Additional Contract Warranty Provisions for Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Warranty Provisions for Supplies of a Noncomplex Nature. 552.246-77 Section 552.246-77 Federal Acquisition... a Noncomplex Nature. As prescribed in 546.710(a), insert the following clause in solicitations and contracts that include FAR 52.246-17, Warranty of Supplies of a Noncomplex Nature. Additional...

  5. 48 CFR 52.246-18 - Warranty of Supplies of a Complex Nature.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Complex Nature. 52.246-18 Section 52.246-18 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-18 Warranty of Supplies of a Complex Nature. As prescribed in 46.710(b)(1), insert a clause substantially as follows: Warranty of Supplies of a Complex Nature (MAY 2001) (a) Definitions. As used in...

  6. 48 CFR 552.246-77 - Additional Contract Warranty Provisions for Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Warranty Provisions for Supplies of a Noncomplex Nature. 552.246-77 Section 552.246-77 Federal Acquisition... a Noncomplex Nature. As prescribed in 546.710(a), insert the following clause in solicitations and contracts that include FAR 52.246-17, Warranty of Supplies of a Noncomplex Nature. Additional...

  7. 48 CFR 52.246-18 - Warranty of Supplies of a Complex Nature.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Complex Nature. 52.246-18 Section 52.246-18 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-18 Warranty of Supplies of a Complex Nature. As prescribed in 46.710(b)(1), insert a clause substantially as follows: Warranty of Supplies of a Complex Nature (MAY 2001) (a) Definitions. As used in...

  8. 48 CFR 52.246-17 - Warranty of Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Noncomplex Nature. 52.246-17 Section 52.246-17 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-17 Warranty of Supplies of a Noncomplex Nature. As prescribed in 46.710(a)(1), insert a clause substantially as follows: Warranty of Supplies of a Noncomplex Nature (JUN 2003) (a)...

  9. 48 CFR 552.246-77 - Additional Contract Warranty Provisions for Supplies of a Noncomplex Nature.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Warranty Provisions for Supplies of a Noncomplex Nature. 552.246-77 Section 552.246-77 Federal Acquisition... a Noncomplex Nature. As prescribed in 546.710(a), insert the following clause in solicitations and contracts that include FAR 52.246-17, Warranty of Supplies of a Noncomplex Nature. Additional...

  10. 24 CFR 266.30 - Nonapplicability of 24 CFR part 246.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Nonapplicability of 24 CFR part 246. 266.30 Section 266.30 Housing and Urban Development Regulations Relating to Housing and Urban... General Provisions § 266.30 Nonapplicability of 24 CFR part 246. The provisions of 24 CFR part 246 do...

  11. 24 CFR 266.30 - Nonapplicability of 24 CFR part 246.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Nonapplicability of 24 CFR part 246. 266.30 Section 266.30 Housing and Urban Development Regulations Relating to Housing and Urban... General Provisions § 266.30 Nonapplicability of 24 CFR part 246. The provisions of 24 CFR part 246 do...

  12. 48 CFR 1852.246-71 - Government contract quality assurance functions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... following functions at the locations indicated: Item Quality Assurance Function Location (End of clause) ... quality assurance functions. 1852.246-71 Section 1852.246-71 Federal Acquisition Regulations System... CLAUSES Texts of Provisions and Clauses 1852.246-71 Government contract quality assurance functions....

  13. 48 CFR 1852.246-71 - Government contract quality assurance functions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... following functions at the locations indicated: Item Quality Assurance Function Location (End of clause) ... quality assurance functions. 1852.246-71 Section 1852.246-71 Federal Acquisition Regulations System... CLAUSES Texts of Provisions and Clauses 1852.246-71 Government contract quality assurance functions....

  14. 48 CFR 1852.246-71 - Government contract quality assurance functions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... following functions at the locations indicated: Item Quality Assurance Function Location (End of clause) ... quality assurance functions. 1852.246-71 Section 1852.246-71 Federal Acquisition Regulations System... CLAUSES Texts of Provisions and Clauses 1852.246-71 Government contract quality assurance functions....

  15. 40 CFR 246.201-6 - Recommended procedures: Transportation to market.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Transportation to market. 246.201-6 Section 246.201-6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Procedures § 246.201-6 Recommended procedures: Transportation to market. Transportation to market may...

  16. 40 CFR 246.201-6 - Recommended procedures: Transportation to market.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Transportation to market. 246.201-6 Section 246.201-6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Procedures § 246.201-6 Recommended procedures: Transportation to market. Transportation to market may...

  17. 40 CFR 246.201-6 - Recommended procedures: Transportation to market.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Transportation to market. 246.201-6 Section 246.201-6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Procedures § 246.201-6 Recommended procedures: Transportation to market. Transportation to market may...

  18. 48 CFR 252.246-7004 - Safety of Facilities, Infrastructure, and Equipment for Military Operations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., Infrastructure, and Equipment for Military Operations. 252.246-7004 Section 252.246-7004 Federal Acquisition..., Infrastructure, and Equipment for Military Operations. As prescribed in 246.270-4, use the following clause: Safety of Facilities, Infrastructure, and Equipment for Military Operations (OCT 2010) (a)...

  19. 48 CFR 246.270 - Safety of facilities, infrastructure, and equipment for military operations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Safety of facilities, infrastructure, and equipment for military operations. 246.270 Section 246.270 Federal Acquisition Regulations... ASSURANCE Contract Quality Requirements 246.270 Safety of facilities, infrastructure, and equipment...

  20. 48 CFR 246.270 - Safety of facilities, infrastructure, and equipment for military operations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Safety of facilities, infrastructure, and equipment for military operations. 246.270 Section 246.270 Federal Acquisition Regulations... ASSURANCE Contract Quality Requirements 246.270 Safety of facilities, infrastructure, and equipment...

  1. 48 CFR 252.246-7004 - Safety of Facilities, Infrastructure, and Equipment for Military Operations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., Infrastructure, and Equipment for Military Operations. 252.246-7004 Section 252.246-7004 Federal Acquisition..., Infrastructure, and Equipment for Military Operations. As prescribed in 246.270-4, use the following clause: Safety of Facilities, Infrastructure, and Equipment for Military Operations (OCT 2010) (a)...

  2. 48 CFR 246.270 - Safety of facilities, infrastructure, and equipment for military operations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Safety of facilities, infrastructure, and equipment for military operations. 246.270 Section 246.270 Federal Acquisition Regulations... ASSURANCE Contract Quality Requirements 246.270 Safety of facilities, infrastructure, and equipment...

  3. 48 CFR 52.246-11 - Higher-Level Contract Quality Requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Higher-Level Contract Quality Requirement. 52.246-11 Section 52.246-11 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52.246-11...

  4. 48 CFR 52.246-11 - Higher-Level Contract Quality Requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Higher-Level Contract Quality Requirement. 52.246-11 Section 52.246-11 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52.246-11...

  5. 10 CFR 431.246 - Energy conservation standards and their effective dates.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Energy conservation standards and their effective dates. 431.246 Section 431.246 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Unit Heaters Energy Conservation Standards § 431.246...

  6. 10 CFR 431.246 - Energy conservation standards and their effective dates.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Energy conservation standards and their effective dates. 431.246 Section 431.246 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Unit Heaters Energy Conservation Standards § 431.246...

  7. 10 CFR 431.246 - Energy conservation standards and their effective dates.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Energy conservation standards and their effective dates. 431.246 Section 431.246 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Unit Heaters Energy Conservation Standards § 431.246...

  8. 10 CFR 431.246 - Energy conservation standards and their effective dates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Energy conservation standards and their effective dates. 431.246 Section 431.246 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Unit Heaters Energy Conservation Standards § 431.246...

  9. 10 CFR 431.246 - Energy conservation standards and their effective dates.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Energy conservation standards and their effective dates. 431.246 Section 431.246 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Unit Heaters Energy Conservation Standards § 431.246...

  10. 48 CFR 52.246-24 - Limitation of Liability-High-Value Items.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...-High-Value Items. 52.246-24 Section 52.246-24 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.246-24 Limitation of Liability—High-Value Items. As prescribed in 46.805, insert the following clause: Limitation of Liability—High-Value Items (FEB 1997) (a) Except as provided...

  11. 48 CFR 52.246-24 - Limitation of Liability-High-Value Items.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Limitation of Liability-High-Value Items. 52.246-24 Section 52.246-24 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52.246-24 Limitation...

  12. 48 CFR 52.246-24 - Limitation of Liability-High-Value Items.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...-High-Value Items. 52.246-24 Section 52.246-24 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.246-24 Limitation of Liability—High-Value Items. As prescribed in 46.805, insert the following clause: Limitation of Liability—High-Value Items (FEB 1997) (a) Except as provided...

  13. 48 CFR 52.246-24 - Limitation of Liability-High-Value Items.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-High-Value Items. 52.246-24 Section 52.246-24 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.246-24 Limitation of Liability—High-Value Items. As prescribed in 46.805, insert the following clause: Limitation of Liability—High-Value Items (FEB 1997) (a) Except as provided...

  14. 48 CFR 52.246-24 - Limitation of Liability-High-Value Items.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-High-Value Items. 52.246-24 Section 52.246-24 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.246-24 Limitation of Liability—High-Value Items. As prescribed in 46.805, insert the following clause: Limitation of Liability—High-Value Items (FEB 1997) (a) Except as provided...

  15. 40 CFR 246.201-9 - Recommended procedures: Public information and education.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Public information and education. 246.201-9 Section 246.201-9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.201-9...

  16. 40 CFR 246.200-10 - Recommended procedures: Public information and education.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Public information and education. 246.200-10 Section 246.200-10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOURCE SEPARATION FOR MATERIALS RECOVERY GUIDELINES Requirements and Recommended Procedures § 246.200-10...

  17. 48 CFR 52.246-9 - Inspection of Research and Development (Short Form).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Development (Short Form). 52.246-9 Section 52.246-9 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-9 Inspection of Research and Development (Short Form). As prescribed in 46.309, insert the following clause: Inspection of Research and Development (Short Form) (APR 1984) The Government has...

  18. 48 CFR 52.246-9 - Inspection of Research and Development (Short Form).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Development (Short Form). 52.246-9 Section 52.246-9 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-9 Inspection of Research and Development (Short Form). As prescribed in 46.309, insert the following clause: Inspection of Research and Development (Short Form) (APR 1984) The Government has...

  19. 48 CFR 246.270 - Safety of facilities, infrastructure, and equipment for military operations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Safety of facilities, infrastructure, and equipment for military operations. 246.270 Section 246.270 Federal Acquisition Regulations... ASSURANCE Contract Quality Requirements 246.270 Safety of facilities, infrastructure, and equipment...

  20. 48 CFR 252.246-7004 - Safety of Facilities, Infrastructure, and Equipment for Military Operations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., Infrastructure, and Equipment for Military Operations. 252.246-7004 Section 252.246-7004 Federal Acquisition..., Infrastructure, and Equipment for Military Operations. As prescribed in 246.270-4, use the following clause: SAFETY OF FACILITIES, INFRASTRUCTURE, AND EQUIPMENT FOR MILITARY OPERATIONS (OCT 2010) (a)...

  1. 48 CFR 52.246-2 - Inspection of Supplies-Fixed-Price.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-Fixed-Price. 52.246-2 Section 52.246-2 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.246-2 Inspection of Supplies—Fixed-Price. As prescribed in 46.302, insert the following clause: Inspection of Supplies—Fixed-Price (AUG 1996) (a) Definition. Supplies, as used in this clause, includes...

  2. Solidification Effects in MAR-M246(Hf) Alloy

    NASA Technical Reports Server (NTRS)

    Johnston, M. H.; Parr, R. A.

    1987-01-01

    Fatigue properties degraded with crystallographic orientations greater than 10 degrees from {001} axis. Influence of solidification and heat-treatment parameters on structure and fatigue properties of nickel-based superalloy MAR-M246(Hf) described in 24-page report. Superalloys have high strength and corrosion resistance at temperatures up to 1,400 degrees C; their uses range from petrochemical equipment to marine, industrial, aircraft, and vehicular gas turbines.

  3. Preparation of actinide targets by electrodeposition

    NASA Astrophysics Data System (ADS)

    Trautmann, N.; Folger, H.

    1989-10-01

    Actinide targets with varying thicknesses on different substrates have been prepared by electrodeposition either from aqueous solutions or from solutions of their nitrates in isopropyl alcohol. With these techniques the actinides can be deposited almost quantitatively on various backing materials within 15 to 30 min. Targets of thorium, uranium, neptunium, plutonium, americium, curium and californium with areal densities from almost carrier-free up to 1.4 mg/cm 2 on thin beryllium, carbon, titanium, tantalum and platinum foils have been prepared. In most cases, prior to the deposition, the actinides had to be purified chemically and for some of them, due to the limited amount of material available, recycling procedures were required. Applications of actinide targets in heavy-ion reactions are briefly discussed.

  4. Synthesis and crystalline phase of monazite-type Ce1-xGdxPO4 solid solutions for immobilization of minor actinide curium

    NASA Astrophysics Data System (ADS)

    Yang, Hang; Teng, Yuancheng; Ren, Xuetan; Wu, Lang; Liu, Haichang; Wang, Shanlin; Xu, Liuyang

    2014-01-01

    Gadolinium (Gd3+) was used to simulate trivalent minor actinide curium (Cm3+), and monazite-type solid solutions with composition of Ce1-xGdxPO4 (x = 0-1) were prepared by the solid state reaction method using Ce2(C2O4)3·10H2O, NH4H2PO4, and Gd2O3 as starting materials. The effects of Gd content on the crystalline phase and microstructure of Ce1-xGdxPO4 solid solutions were investigated, and the calcining parameters of Ce0.9Gd0.1PO4 solid solution were optimized by means of XRD, TG-DSC and SEM. The results show that pure monazite-type crystalline phase was obtained for the Ce1-xGdxPO4 with x = 0-1, and the incorporation of minor actinide curium simulated by gadolinium in monazite was confirmed. The change of Gd content had no significant effect on the microstructure of Ce1-xGdxPO4 solid solutions, and the grain size was approximately 0.1-1 μm. Besides, the optimal calcining temperature and holding time of Ce0.9Gd0.1PO4 solid solution were 1000 °C and 2 h, respectively.

  5. Sensitive determination of 2,4,6-trichloroanisole in water samples by ultrasound assisted emulsification microextraction prior to gas chromatography-tandem mass spectrometry analysis.

    PubMed

    Fontana, Ariel R; Altamirano, Jorgelina C

    2010-06-15

    A novel application of an ultrasound assisted emulsification microextraction (USAEME) technique is proposed for the extraction and preconcentration of 2,4,6-trichloroanisole (2,4,6-TCA) from water samples prior to its determination by gas chromatography-tandem mass spectrometry (GC-MS/MS). USAEME employs a non-polar high-density solvent (extractant solvent), which forms an oil-in-water emulsion (O/W) in the aqueous sample bulk assisted by ultrasonic radiation. Several factors including, solvent type and volume, extraction time, extraction temperature, shaking mode and matrix modifiers were studied and optimized over the relative recovery of the target analyte. An aliquot of 5mL water sample was conditioned by adding 150microL 6.15molL(-1) sodium chloride and 300microL 0.05molL(-1) phosphate buffer (pH 6), and finally extracted with 40microL chloroform by using USAEME technique. Under the optimal experimental conditions 2,4,6-TCA was quantitatively extracted achieving an enrichment factor (EF) of 555. The detection limit (LOD), calculated as three times the signal-to-noise ratio (S/N), was 0.2ngL(-1) and the RSD was 6.3% (n=5) when 1ngL(-1) 2,4,6-TCA standard mixture was analyzed. The coefficients of estimation of the calibration curves obtained following the proposed methodology was >or=0.997 and the linear working range was 1-5000ngL(-1). Finally, the proposed technique was successfully applied for extraction and determination of the 2,4,6-TCA in water samples. Recovery studies lead values >or=94%, which showed a successfully robustness of the analytical methodology for determination of nanogram per liter of 2,4,6-TCA in water samples. PMID:20441935

  6. Two-stage biotransformation of 2,4,6-trinitrotoluene

    SciTech Connect

    VanderLoop, S.L.; Suidan, M.T.; Moteleb, M.A.; Maloney, S.W.

    1995-12-31

    TNT is the explosive most widely used by the military, but current technologies for treating munitions production wastewater are costly and produce a secondary waste, spent GAC. Bioremediation holds promise as a more effective and less costly treatment strategy. An anaerobic fluidized-bed granular activated carbon (GAC) bioreactor in series with an activated sludge reactor was used to treat 2,4,6-trinitrotoluene (TNT). A wastewater solution of 100 mg/L 2,4,6-TNT, as well as carbonate buffer and nutrient solutions, were fed to the anaerobic reactor. Ethanol and ammonia were supplied for microbial growth at 540 mg/L and 20 mg/L, respectively. The mixed anaerobic culture completely transformed the TNT to unknown products. Attempts to detect these products by gas chromatography (GC) and high-performance liquid chromatography (HPLC) were unsuccessful. The effluent from this reactor was treated further in an activated sludge system. The TNT transformation products were partially oxidized in the aerobic stage, resulting in recovery of 91% of the total influent nitrogen as ammonia, nitrate, and biomass. This corresponds to recovery of 82% of influent TNT nitrogen.

  7. APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines.

    PubMed

    Deben, Christophe; Lardon, Filip; Wouters, An; Op de Beeck, Ken; Van den Bossche, Jolien; Jacobs, Julie; Van Der Steen, Nele; Peeters, Marc; Rolfo, Christian; Deschoolmeester, Vanessa; Pauwels, Patrick

    2016-06-01

    APR-246 (PRIMA-1(Met)) is able to bind mutant p53 and restore its normal conformation and function. The compound has also been shown to increase intracellular ROS levels. Importantly, the poly-[ADP-ribose] polymerase-1 (PARP-1) enzyme plays an important role in the repair of ROS-induced DNA damage. We hypothesize that by blocking this repair with the PARP-inhibitor AZD2281 (olaparib), DNA damage would accumulate in the cell leading to massive apoptosis. We observed that APR-246 synergistically enhanced the cytotoxic response of olaparib in TP53 mutant non-small cell lung cancer cell lines, resulting in a strong apoptotic response. In the presence of wild type p53 a G2/M cell cycle block was predominantly observed. NOXA expression levels were significantly increased in a TP53 mutant background, and remained unchanged in the wild type cell line. The combined treatment of APR-246 and olaparib induced cell death that was associated with increased ROS production, accumulation of DNA damage and translocation of p53 to the mitochondria. Out data suggest a promising targeted combination strategy in which the response to olaparib is synergistically enhanced by the addition of APR-246, especially in a TP53 mutant background. PMID:26975633

  8. Destruction of 2,4,6-trinitrotoluene by Fenton oxidation

    SciTech Connect

    Li, Z.M.; Comfort, S.D.; Shea, P.J.

    1997-03-01

    Past disposal practices at munitions production facilities have generated numerous acres of 2,4,6-trinitrotoluene (TNT)-contaminated soil. We determined the potential of the Fenton reagent (Fe{sup 2+} and H{sub 2}O{sub 2}) to remediate TNT contamination in water, aqueous extracts of contaminated soil, and soil-water slurries. The effects of H{sub 2}O{sub 2} and Fe{sup 2+} concentrations, solution pH, temperature, and initial TNT concentration on transformation and mineralization rates were evaluated. Treating an aqueous TNT solution (70 mg TNT L{sup -1}) with Fenton reagent (1% H{sub 2}O{sub 2}, 80 mg Fe{sup 2+} L{sup -1}) in the dark resulted in 100% destruction of TNT within 24 h. This coincided with 40% mineralization. Subsequent exposure to light resulted in >90% mineralization. We observed generation of 2,4,6-trinitrobenzoic acid and 1,3,5-trinitrobenzene within 15 min following Fenton oxidation of TNT. This indicates that initial TNT destruction likely occurs by methyl group oxidation and decarboxylation. Subsequent transformations involve nitro moiety removal with ring hydroxylation and cleavage, as evidenced by the stoichiometric recovery of TNT-nitrogen as NO{sub 3}{sup -} and production of oxalic acid as the primary C-containing end product. Upon exposure to light, Fe(II) was regenerated and the oxalate produced from 14C-TNT oxidation disappeared; this coincided with a decrease in solution {sup 14}C activity. Similar observations were made when {sup 14}C-oxalic acid was the starting substrate. Fenton oxidation was also effective in destroying TNT in aqueous extracts of contaminated soil and soil-water slurries. Experimental data provide evidence that the Fenton reagent can effectively remediate TNT-contaminated water and soil. 39 refs., 8 figs., 1 tab.

  9. 10 CFR 72.246 - Issuance of amendment to a certificate of compliance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Issuance of amendment to a certificate of compliance. 72.246 Section 72.246 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER...

  10. 40 CFR 81.246 - Northern Alaska Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northern Alaska Intrastate Air Quality Control Region. 81.246 Section 81.246 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... 1956 Election Districts 18-23, inclusive, as described in Article XIV, section 3 of the Constitution...

  11. 48 CFR 52.246-8 - Inspection of Research and Development-Cost-Reimbursement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Inspection of Research and Development-Cost-Reimbursement. 52.246-8 Section 52.246-8 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses...

  12. 19 CFR 10.246 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Maintenance of records and submission of Certificate by importer. 10.246 Section 10.246 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. Andean Trade Promotion and...

  13. 19 CFR 10.246 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Maintenance of records and submission of Certificate by importer. 10.246 Section 10.246 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. Andean Trade Promotion and...

  14. 19 CFR 10.246 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Maintenance of records and submission of Certificate by importer. 10.246 Section 10.246 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. Andean Trade Promotion and...

  15. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Stars and Stripes (S&S) Board of Directors E... DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and...

  16. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 2 2011-07-01 2011-07-01 false Stars and Stripes (S&S) Board of Directors E... DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and...

  17. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Stars and Stripes (S&S) Board of Directors E... DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and...

  18. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Stars and Stripes (S&S) Board of Directors E... DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and...

  19. 48 CFR 246.701 - Definitions as used in this subpart.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-17, Warranty of Supplies of a Noncomplex Nature; FAR 52.246-18, Warranty of Supplies of a Complex... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Definitions as used in... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Warranties 246.701...

  20. 19 CFR 10.246 - Maintenance of records and submission of Certificate by importer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Maintenance of records and submission of Certificate by importer. 10.246 Section 10.246 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY ARTICLES CONDITIONALLY FREE, SUBJECT TO A REDUCED RATE, ETC. Andean Trade Promotion and...

  1. 7 CFR 246.16a - Infant formula and authorized foods cost containment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Infant formula and authorized foods cost containment. 246.16a Section 246.16a Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN...

  2. 48 CFR 1852.246-71 - Government contract quality assurance functions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Government contract quality assurance functions. 1852.246-71 Section 1852.246-71 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses...

  3. 7 CFR 246.16a - Infant formula and authorized foods cost containment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Infant formula and authorized foods cost containment. 246.16a Section 246.16a Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL SUPPLEMENTAL NUTRITION PROGRAM FOR WOMEN, INFANTS AND CHILDREN...

  4. 49 CFR 195.246 - Installation of pipe in a ditch.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Installation of pipe in a ditch. 195.246 Section... HAZARDOUS LIQUIDS BY PIPELINE Construction § 195.246 Installation of pipe in a ditch. (a) All pipe installed... the possibility of damage to the pipe. (b) Except for pipe in the Gulf of Mexico and its inlets...

  5. 30 CFR 250.246 - What mineral resource conservation information must accompany the DPP or DOCD?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... must accompany the DPP or DOCD? 250.246 Section 250.246 Mineral Resources BUREAU OF OCEAN ENERGY... information, as applicable, must accompany your DPP or DOCD: (a) Technology and reservoir engineering practices and procedures. A description of the technology and reservoir engineering practices and...

  6. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Stars and Stripes (S&S) Board of Directors E Appendix E to Part 246 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF.... E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and...

  7. 28 CFR 2.46 - Execution of warrant and service of summons.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Execution of warrant and service of summons. 2.46 Section 2.46 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND... procedural rights under the Commission's regulations and the possible actions which may be taken by...

  8. 48 CFR 252.246-7005 - Notice of Warranty Tracking of Serialized Items.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Notice of Warranty Tracking of Serialized Items. 252.246-7005 Section 252.246-7005 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION...

  9. 48 CFR 252.246-7005 - Notice of Warranty Tracking of Serialized Items.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Notice of Warranty Tracking of Serialized Items. 252.246-7005 Section 252.246-7005 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION...

  10. 48 CFR 252.246-7005 - Notice of Warranty Tracking of Serialized Items.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Notice of Warranty Tracking of Serialized Items. 252.246-7005 Section 252.246-7005 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION...

  11. 48 CFR 252.246-7005 - Notice of Warranty Tracking of Serialized Items.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Notice of Warranty Tracking of Serialized Items. 252.246-7005 Section 252.246-7005 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION...

  12. 48 CFR 246.202-4 - Higher-level contract quality requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Higher-level contract quality requirements. 246.202-4 Section 246.202-4 Federal Acquisition Regulations System DEFENSE... requirements, including nongovernment quality system standards adopted to meet DoD needs, are listed in the...

  13. 48 CFR 246.202-4 - Higher-level contract quality requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Higher-level contract quality requirements. 246.202-4 Section 246.202-4 Federal Acquisition Regulations System DEFENSE... requirements, including nongovernment quality system standards adopted to meet DoD needs, are listed in the...

  14. 48 CFR 246.202-4 - Higher-level contract quality requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Higher-level contract quality requirements. 246.202-4 Section 246.202-4 Federal Acquisition Regulations System DEFENSE... requirements, including nongovernment quality system standards adopted to meet DoD needs, are listed in the...

  15. 48 CFR 246.202-4 - Higher-level contract quality requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Higher-level contract quality requirements. 246.202-4 Section 246.202-4 Federal Acquisition Regulations System DEFENSE... requirements, including nongovernment quality system standards adopted to meet DoD needs, are listed in the...

  16. Development of an analytical method to quantify PBDEs, OH-BDEs, HBCDs, 2,4,6-TBP, EH-TBB, and BEH-TEBP in human serum.

    PubMed

    Butt, Craig M; Miranda, Marie Lynn; Stapleton, Heather M

    2016-04-01

    Polybrominated diphenyl ethers (PBDEs) flame retardants (FRs) were phased-out in the mid-2000s (penta- and octaBDE) and 2013 (decaBDE); however, their hydroxylated metabolites (OH-BDEs) are still commonly detected in human serum. Today, novel FRs such as Firemaster® 550, a mixture that contains two brominated compounds, EH-TBB and BEH-TEBP are used as replacements for PBDEs in some applications, and there is a need to develop a comprehensive analytical method to assess exposure to both legacy PBDEs and novel FRs. This study developed a solid-phase extraction (SPE)-based method to analyze PBDEs, OH-BDEs, 2,4,6-tribromophenol (TBP), hexabromocylcododecane isomers (HBCDs), EH-TBB, and BEH-TEBP in human serum. Briefly, serum proteins were first denatured with formic acid, and then the target analytes were isolated using a SPE column. Finally, the extract was cleaned and fractioned using a silica SPE column. Method performance was assessed by spiking fetal bovine serum with 1-2 ng of the target analytes, and method accuracy was quantified by comparison to a serum Standard Reference Material (SRM). The developed method showed good recovery and accuracy for all target analytes with the exception of the very low and very high molecular weight PBDE congeners. Using this method, 43 serum samples collected from the Healthy Pregnancy, Healthy Baby Study (HPHB) cohort in Durham, NC, USA were analyzed for FRs. A novel finding was the ubiquitous detection of 2,4,6-TBP, at levels greater than the individual PBDE congeners. Furthermore, 2,4,6-TBP was positively correlated with PBDEs, suggesting that they may have a similar source of exposure, or that 2,4,6-TBP may result from metabolism of PBDEs in vivo. PMID:26864867

  17. 25 CFR 1000.246 - Must an AFA that contains a construction project or activity incorporate provisions of Federal...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Must an AFA that contains a construction project or activity incorporate provisions of Federal construction standards? 1000.246 Section 1000.246 Indians OFFICE... Construction § 1000.246 Must an AFA that contains a construction project or activity incorporate provisions...

  18. 33 CFR 148.246 - When is a document considered filed and where should I file it?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... filed and where should I file it? 148.246 Section 148.246 Navigation and Navigable Waters COAST GUARD... Formal Hearings § 148.246 When is a document considered filed and where should I file it? (a) If a document to be filed is submitted by mail, it is considered filed on the date it is postmarked. If...

  19. 33 CFR 148.246 - When is a document considered filed and where should I file it?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... filed and where should I file it? 148.246 Section 148.246 Navigation and Navigable Waters COAST GUARD... Formal Hearings § 148.246 When is a document considered filed and where should I file it? (a) If a document to be filed is submitted by mail, it is considered filed on the date it is postmarked. If...

  20. Solubility of 2,4,6-trinitrotoluene (TNT) in water

    SciTech Connect

    Ro, K.S.; Venugopal, A.; Adrian, D.D.; Constant, D.; Valsaraj, K.T.; Thibodeaux, L.J.; Qaisi, K.; Roy, D.

    1996-07-01

    Current literature values of 2,4,6-trinitrotoluene (TNT) solubility in water vary widely from 100 to 200 mg/L at room temperature. The authors investigated the effects of temperature and pH on the solubility of both reference TNT and field neat TNT obtained from the Alabama Army Ammunition Plant (AAAP), Childersburg, AL. The TNT solubility determined from this study was significantly lower than that of Taylor and Rinkenbach, which was cited by several reference chemical handbooks and articles. However, the values reported by the Merck Index and the Lange`s Handbook of Chemistry compared well with the authors` values. TNT solubility dropped rapidly as the pH increased. Three unknown HPLC peaks were observed at high pH, indicating a possibility of forming unknown transformation products. Both reference and field neat TNT solubility agreed well. A semiempirical solubility correlation was developed to predict the solubility of TNT at a temperature range from 6 C to 42 C.

  1. Structural and vibrational study of [Mo7O24]6- and [W7O24]6-.

    PubMed

    Courcot, Blandine; Bridgeman, Adam J

    2009-10-01

    Density functional methods have been used to investigate the structure and the vibrational modes of [M7O24]6- isopolyanions of molybdenum and tungsten. Relativistic effects have been considered through the zeroth-order regular approximation (ZORA) and interactions with an aqueous environment modeled by the COSMO approach. A structural study of the two compounds has been performed, and the geometrical parameters obtained are in good agreement with experimental data. However, when the solvent is introduced in the model, deviations are found, especially for some tungsten-oxygen bonds which involve pseudoterminal oxygens. Thus, different computational strategies have been tested to reject any reliance on the COSMO model and the optimization algorithms. The variations compared to solid-state bond lengths appear to be due to the solvent. Infrared and Raman spectra have been also calculated in the gas phase and in water leading, for the first time, to a detailed assignment of the vibrational frequencies. The vibrational contributions of the aminopyridinium counterion [C5H7N2]+ have been isolated, improving the assignment of experimental spectra. Inclusion of solvent causes a shift toward lower frequencies and an increase in the intensity of the peaks. Spectra obtained using pseudo-gas-phase calculations reproduce the experimental data most satisfactorily, especially when the experiments are performed on the solid state. PMID:19736923

  2. Transformation ability of fungi isolated from cork and grape to produce 2,4,6-trichloroanisole from 2,4,6-trichlorophenol.

    PubMed

    Maggi, L; Mazzoleni, V; Fumi, M D; Salinas, M R

    2008-03-01

    The ability of eight fungal strains to transform 2,4,6-trichlorophenol (TCP) to 2,4,6-trichloroanisole (TCA) was studied. These fungi were isolated from cork, belonging to the genera Penicillium, Aspergillus, Trichoderma and Chrysonilia, and from grapes Botrytis cinerea. All, except Chrysonilia, produced TCA when grown directly on cork in the presence of TCP, Aspergillus and Botrytis cinerea being the ones with the highest level of production. It is the first time that Botrytis cinerea, a microorganism often present on grapes and in winery environments, has been shown to transform TCP into TCA. This result can partially explain the wine cork taint before being bottled. PMID:18311620

  3. COMPARISON OF BIOMARKERS IN WORKERS EXPOSED TO 2,4,6-TRINITROTOLUENE

    EPA Science Inventory

    2,4,6-Trinitrotoluene (TNT) is an important occupational and environmental pollutant. In TNT-exposed humans, the notable toxic manifestations have included aplastic anemia, toxic hepatitis, cataracts, hepatomegaly, and liver cancer. Therefore, we developed methods to biomonitor w...

  4. Toxicological studies on 2,4,6-tribromoanisole.

    PubMed

    Koschier, F; Gallo, M A; Feng, X; Baxter, G E; Preston, R; Stevens, K; Powers, W

    2011-09-01

    TBA, or 2,4,6-tribromoanisole, is a musty-smelling metabolite of 2,4,6-tribromophenol that is used as a flame retardant and an antifungal agent for wooden pallets and packaging materials. The compound can impart its peculiar, often offensive, odor on product packaging to the concern of consumers for the safety of the package contents. These studies were conducted to evaluate the safety of TBA to humans ingesting products tainted with TBA. In addition to the 28-day oral study, a bacterial reverse mutation study was conducted, and confirmed that TBA was not mutagenic. To evaluate oral safety, TBA was evaluated in single dose and 5-day and 4-week repeated dose oral toxicity studies in rats. The test article, administered in single gavage doses of 2000, 5000 and 7500 mg/kg body weight (bw), in 5 daily repeated doses of 1000, 2000 or 3000 mg/kg bw/day or in 28 daily oral gavage doses of 0 001, 0.01, 100, and 1000 mg/kg bw/day did not result in any deaths. Also, the single and repeat dose studies resulted in no significant differences between control and treated groups on body weight gain, food consumption, clinical observations, blood biochemical values, and hematology findings. Treatment-related adverse findings were only detected in male rats during repeated dose studies and were associated with high plasma concentrations of TBA. The test article-related finding of hyaline droplets in the cortical tubular epithelium of kidneys was associated with increases in α(2 μ)-globulin content in the kidneys as indicated by the intensity of immunohistochemical staining. These findings were correlated with an increased weight of kidneys in males administered 1000mg/kgbw/day for 28days. Chemical induction of hyaline droplets containing α(2μ)-globulin in the renal proximal tubule is a process unique to the male rat and is not relevant for human risk assessment. Findings of increased liver weight with minimal centrilobular to diffuse hepatocellular hypertrophy in males treated

  5. Penta- and 2,4,6-tri-chlorophenol biodegradation during municipal solid waste anaerobic digestion.

    PubMed

    Limam, Intissar; Limam, Rim Driss; Mezni, Mohamed; Guenne, Angéline; Madigou, Céline; Driss, Mohamed Ridha; Bouchez, Théodore; Mazeas, Laurent

    2016-08-01

    In this study isotopic tracing using (13)C labelled pentachlorophenol (PCP) and 2,4,6-trichlorophenol (2,4,6-TCP) is proposed as a tool to distinguish the loss of PCP and 2,4,6-TCP due to biodegradation from other physical processes. This isotopic approach was applied to accurately assess in situ PCP and 2,4,6-TCP degradation under methanogenic conditions in several microcosms made up of household waste. These microcosms were incubated in anaerobic conditions at 35°C (mesophilic) and 55°C (thermophilic) without agitation. The volume of biogas produced (CH4 and CO2), was followed for a period of 130 days. At this stage of stable methanogenesis, (13)C6-PCP and (13)C6-2,4,6-TCP were introduced anaerobically in microcosms and its monitoring at mesophilic and thermophilic conditions was performed in parallel by gas chromatography mass spectrometry (GC-MS) and gas chromatography isotope-ratio mass spectrometry (GC-IRMS). This study proved the almost total dechlorination of bioavailable PCP and 2,4,6-TCP into 4-CP at 35°C. Nevertheless, high rate adsorption in particular materials of the two compounds was observed. Furthermore, Carbon-13 Nuclear Magnetic Resonance ((13)C-NMR) Spectroscopy analysis of (13)C labelled 2,4,6-TCP mesophilic incubations showed the partial mineralization of 4-CP at 35°C to acetate and then to HCO(3-). Consequently, NMR results confirm the biogas isotopic results indicating the mineralization of (13)C labelled 2,4,6-TCP into (13)C (CH4 and CO2). Concerning (13)C labelled PCP mesophilic incubations, the isotopic composition of the biogas still natural until the day 262. In contrast, no dechlorination was observed at 55°C. Thus PCP and 2,4,6-TCP were persistent in thermophilic conditions. PMID:27151678

  6. Synthesis of Heteroaryl Sulfonamides from Organozinc Reagents and 2,4,6-Trichlorophenyl Chlorosulfate

    PubMed Central

    2016-01-01

    A method for the preparation of aryl and heteroaryl sulfonamides using 2,4,6-trichlorophenyl chlorosulfate (TCPC) is described. The reaction of 2-pyridylzinc reagents with TCPC resulted in 2,4,6-trichlorophenyl (TCP) pyridine-2-sulfonates, and the parent pyridine-2-sulfonate was shown to react with amines. Less electron-rich aryl- and heteroarylzinc reagents reacted with TCPC to afford sulfonyl chlorides that were converted in situ to sulfonamides. PMID:26065317

  7. Pharmacokinetics and metabolism of SRX246: a potent and selective vasopressin 1a antagonist.

    PubMed

    Fabio, Karine M; Guillon, Christophe D; Lu, Shi-Fang; Heindel, Ned D; Brownstein, Michael J; Lacey, Carl J; Garippa, Carrie; Simon, Neal G

    2013-06-01

    SRX246 is a potent, highly selective, orally bioavailable vasopressin 1a receptor antagonist that represents a novel mechanism of action for the treatment of mood disorders. The compound previously showed efficacy in animal models of mood disorders and excellent safety and tolerability in healthy volunteers in phase I clinical trials. In this study, SRX246 was further characterized in rats and dogs. In vitro determinations of permeability, protein binding, hepatocyte metabolism, and cytochrome P450 enzyme inhibition and in vivo assessments of pharmacokinetics were conducted. In parallel artificial membrane permeability assay (PAMPA) and PAMPA-blood-brain barrier models, SRX246 was comparable to highly permeable, orally active pharmaceuticals. SRX246 hydrochloride salt was 95.5 ± 1.7%, 95.9 ± 1.3%, and 98.6 ± 0.4% bound to rat, dog, and human serum proteins, respectively, and was stable in serum after a 4 h incubation at 37°C. P450 enzyme inhibition results showed a very low potential for drug-drug interactions. Metabolism in primary hepatocytes demonstrated that SRX246 was stable in humans and moderately metabolized in dogs and rats. Plasma pharmacokinetics findings showed a half-life (T½ ) of 2 and 6 h in rat and dog, respectively. Rat brain levels following a single oral dose were approximately 20% of plasma values with a T½ of 6 h. The observed profile for SRX246 supports further development. PMID:23471831

  8. Inhibitory activities against rice pathogens of 8-hydroxy-2,4,6-octatriynamide from Agrocybe sp.

    PubMed

    Zheng, Yongbiao; Xu, Xiaoping; Wu, Yabin

    2016-03-01

    8-Hydroxy-2,4,6-octatriynamide, a natural polyacetylene with inhibitory activities against rice pathogens, was isolated from the liquid fermentation broth of strain Agrocybe sp. YB2005 during screening for new natural chemical agents to control rice pathogens. 8-hydroxy-2,4,6-octatriynamide was purified by consecutive chromatography over a Cl8 reversed phase silica gel, sephadex LH-20 and silica gel. The chemical structure of 8-hydroxy-2,4,6-octatriynamide was elucidated through spectroscopic analyses, including 1D- and 2D-NMR, ESI mass spectrometry and X-ray single crystal diffraction. Bioassays showed that 8-hydroxy-2,4,6-octatriynamide could significantly inhibit growth of Xanthomonas oryzae with an MIC of 53.1 μM in a 96-well plate and the growth of Rhizoctonia solani at 1.02 mM in a 24-well plate. When rice leaves were inoculated with Magnaporthe grisea and cultured in artificial nutrition liquid containing 0.34 mM 8-hydroxy-2,4,6-octatriynamide, no rice blast was observed. The present study implied that 8-hydroxy-2,4,6-octatriynamide could be a candidate agent against rice pathogens. PMID:26861586

  9. Type B accident investigation board report of the July 2, 1997 curium intake by shredder operator at Building 513 Lawrence Livermore National Laboratory, Livermore, California. Final report

    SciTech Connect

    1997-08-01

    On July 2, 1997 at approximately 6:00 A.M., two operators (Workers 1 and 2), wearing approved personal protective equipment (PPE), began a shredding operation of HEPA filters for volume reduction in Building 513 (B-513) at Lawrence Livermore National Laboratory (LLNL). The waste requisitions indicated they were shredding filters containing {le} 1 {micro}Ci of americium-241 (Am-241). A third operator (Worker 3) provided support to the shredder operators in the shredding area (hot area) from a room that was adjacent to the shredding area (cold area). At Approximately 8:00 A.M., a fourth operator (Worker 4) relieved Worker 2 in the shredding operation. Sometime between 8:30 A.M. and 9:00 A.M., Worker 3 left the cold area to make a phone call and set off a hand and foot counter in Building 514. Upon discovering the contamination, the shredding operation was stopped and surveys were conducted in the shredder area. Surveys conducted on the workers found significant levels of contamination on their PPE and the exterior of their respirator cartridges. An exit survey of Worker 1 was conducted at approximately 10:05 A.M., and found contamination on his PPE, as well as on the exterior and interior of his respirator. Contamination was also found on his face, chest, back of neck, hair, knees, and mustache. A nose blow indicated significant contamination, which was later determined to be curium-244.

  10. Biological Degradation of 2,4,6-Trinitrotoluene

    PubMed Central

    Esteve-Núñez, Abraham; Caballero, Antonio; Ramos, Juan L.

    2001-01-01

    Nitroaromatic compounds are xenobiotics that have found multiple applications in the synthesis of foams, pharmaceuticals, pesticides, and explosives. These compounds are toxic and recalcitrant and are degraded relatively slowly in the environment by microorganisms. 2,4,6-Trinitrotoluene (TNT) is the most widely used nitroaromatic compound. Certain strains of Pseudomonas and fungi can use TNT as a nitrogen source through the removal of nitrogen as nitrite from TNT under aerobic conditions and the further reduction of the released nitrite to ammonium, which is incorporated into carbon skeletons. Phanerochaete chrysosporium and other fungi mineralize TNT under ligninolytic conditions by converting it into reduced TNT intermediates, which are excreted to the external milieu, where they are substrates for ligninolytic enzymes. Most if not all aerobic microorganisms reduce TNT to the corresponding amino derivatives via the formation of nitroso and hydroxylamine intermediates. Condensation of the latter compounds yields highly recalcitrant azoxytetranitrotoluenes. Anaerobic microorganisms can also degrade TNT through different pathways. One pathway, found in Desulfovibrio and Clostridium, involves reduction of TNT to triaminotoluene; subsequent steps are still not known. Some Clostridium species may reduce TNT to hydroxylaminodinitrotoluenes, which are then further metabolized. Another pathway has been described in Pseudomonas sp. strain JLR11 and involves nitrite release and further reduction to ammonium, with almost 85% of the N-TNT incorporated as organic N in the cells. It was recently reported that in this strain TNT can serve as a final electron acceptor in respiratory chains and that the reduction of TNT is coupled to ATP synthesis. In this review we also discuss a number of biotechnological applications of bacteria and fungi, including slurry reactors, composting, and land farming, to remove TNT from polluted soils. These treatments have been designed to achieve

  11. Preparation of 1,3,5-triamino-2,4,6-trinitrobenzene from 3,5-dichloroanisole

    DOEpatents

    Ott, D.G.; Benziger, T.M.

    1991-03-05

    Preparation of 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) from 3,5-dichloroanisole is described. Nitration of 3,5-dichloroanisole under relatively mild conditions gave 3,5-dichloro-2,4,6-trinitroanisole in high yield and purity. Ammonolysis of this latter compound gave the desired TATB. Another route to TATB was through the treatment of the 3,5-dichloro-2,4,6-trinitroanisole with thionyl chloride and dimethylformamide to yield 1,3,5-trichloro-2,4,6-trinitrobenzene. Ammonolysis of this product produced TATB. 8 figures.

  12. 7 CFR 246.16 - Distribution of funds.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CFR Sections Affected, which appears in the Finding Aids section of the printed volume and at www... funding formula and State agency breastfeeding promotion and support expenditure targets will be issued in... containment measures, curtailment of vendor abuse, and breastfeeding promotional activities. FNS will...

  13. 7 CFR 246.16 - Distribution of funds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CFR Sections Affected, which appears in the Finding Aids section of the printed volume and on GPO... funding formula and State agency breastfeeding promotion and support expenditure targets will be issued in... containment measures, curtailment of vendor abuse, and breastfeeding promotional activities. FNS will...

  14. 7 CFR 246.16 - Distribution of funds.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CFR Sections Affected, which appears in the Finding Aids section of the printed volume and at www... funding formula and State agency breastfeeding promotion and support expenditure targets will be issued in... containment measures, curtailment of vendor abuse, and breastfeeding promotional activities. FNS will...

  15. 7 CFR 246.16 - Distribution of funds.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CFR Sections Affected, which appears in the Finding Aids section of the printed volume and at www... funding formula and State agency breastfeeding promotion and support expenditure targets will be issued in... containment measures, curtailment of vendor abuse, and breastfeeding promotional activities. FNS will...

  16. 7 CFR 246.16 - Distribution of funds.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CFR Sections Affected, which appears in the Finding Aids section of the printed volume and at www... funding formula and State agency breastfeeding promotion and support expenditure targets will be issued in... containment measures, curtailment of vendor abuse, and breastfeeding promotional activities. FNS will...

  17. Determination of the 243,246,248Cm thermal neutron induced fission cross sections

    NASA Astrophysics Data System (ADS)

    Serot, O.; Wagemans, C.; Vermote, S.; Heyse, J.; Soldner, T.; Geltenbort, P.

    2005-11-01

    The minor actinide waste produced in nuclear power plants contains various Cm-isotopes, and transmutation scenarios require improved fission cross section data. The available thermal neutron induced fission cross section data for 243Cm, 246Cm and 248Cm are not very accurate, so new cross section measurements have been performed at the high flux reactor of the ILL in Grenoble (France) under better experimental conditions (highly enriched samples, very intense and clean neutron beam). The measurements were performed at a neutron energy of 5.38 meV, yielding fission cross section values of (1240±28)b for 243Cm, (25±47)mb for 246Cm and (685±84)mb for 248Cm. From these results, thermal fission cross section values of (572±14)b; (12±25)mb and (316±43)mb have been deduced for 243Cm, 246Cm and 248Cm, respectively.

  18. Solidification rate influence on orientation and mechanical properties of MAR-M-246+Hf

    NASA Technical Reports Server (NTRS)

    Hamilton, D.

    1983-01-01

    The influence of solidification rates on the orientation and mechanical properties of MAR-M-246+Hf was studied. The preferred orientation was found to be (001) for single crystals, with all samples with 45 degrees of (001). Tensile tests were performed at room temperature. The anisotropy of directionally solidified MAR-M-246+Hf was demonstrated by gage section deformation. Dendrite arm spacing and crystal growth were found to depend on solidification rates and source material conditions. The greatest strength occurred at lower solidification rates. Some single crystals were grown by control of growth rates without seeding.

  19. Cork taint of wines: role of the filamentous fungi isolated from cork in the formation of 2,4,6-trichloroanisole by o methylation of 2,4,6-trichlorophenol.

    PubMed

    Alvarez-Rodríguez, María Luisa; López-Ocaña, Laura; López-Coronado, José Miguel; Rodríguez, Enrique; Martínez, María Jesús; Larriba, Germán; Coque, Juan-José R

    2002-12-01

    Cork taint is a musty or moldy off-odor in wine mainly caused by 2,4,6-trichloroanisole (2,4,6-TCA). We examined the role of 14 fungal strains isolated from cork samples in the production of 2,4,6-TCA by O methylation of 2,4,6-trichlorophenol (2,4,6-TCP). The fungal strains isolated belong to the genera Penicillium (four isolates); Trichoderma (two isolates); and Acremonium, Chrysonilia, Cladosporium, Fusarium, Mortierella, Mucor, Paecilomyces, and Verticillium (one isolate each). Eleven of these strains could produce 2,4,6-TCA when they were grown directly on cork in the presence of 2,4,6-TCP. The highest levels of bioconversion were carried out by the Trichoderma and Fusarium strains. One strain of Trichoderma longibrachiatum could also efficiently produce 2,4,6-TCA in liquid medium. However, no detectable levels of 2,4,6-TCA production by this strain could be detected on cork when putative precursors other than 2,4,6-TCP, including several anisoles, dichlorophenols, trichlorophenols, or other highly chlorinated compounds, were tested. Time course expression studies with liquid cultures showed that the formation of 2,4,6-TCA was not affected by a high concentration of glucose (2% or 111 mM) or by ammonium salts at concentrations up to 60 mM. In T. longibrachiatum the O methylation of 2,4,6-TCP was catalyzed by a mycelium-associated S-adenosyl-L-methionine (SAM)-dependent methyltransferase that was strongly induced by 2,4,6-TCP. The reaction was inhibited by S-adenosyl-L-homocysteine, an inhibitor of SAM-dependent methylation, suggesting that SAM is the natural methyl donor. These findings increase our understanding of the mechanism underlying the origin of 2,4,6-TCA on cork, which is poorly understood despite its great economic importance for the wine industry, and they could also help us improve our knowledge about the biodegradation and detoxification processes associated with chlorinated phenols. PMID:12450804

  20. Cork Taint of Wines: Role of the Filamentous Fungi Isolated from Cork in the Formation of 2,4,6-Trichloroanisole by O Methylation of 2,4,6-Trichlorophenol

    PubMed Central

    Álvarez-Rodríguez, María Luisa; López-Ocaña, Laura; López-Coronado, José Miguel; Rodríguez, Enrique; Martínez, María Jesús; Larriba, Germán; Coque, Juan-José R.

    2002-01-01

    Cork taint is a musty or moldy off-odor in wine mainly caused by 2,4,6-trichloroanisole (2,4,6-TCA). We examined the role of 14 fungal strains isolated from cork samples in the production of 2,4,6-TCA by O methylation of 2,4,6-trichlorophenol (2,4,6-TCP). The fungal strains isolated belong to the genera Penicillium (four isolates); Trichoderma (two isolates); and Acremonium, Chrysonilia, Cladosporium, Fusarium, Mortierella, Mucor, Paecilomyces, and Verticillium (one isolate each). Eleven of these strains could produce 2,4,6-TCA when they were grown directly on cork in the presence of 2,4,6-TCP. The highest levels of bioconversion were carried out by the Trichoderma and Fusarium strains. One strain of Trichoderma longibrachiatum could also efficiently produce 2,4,6-TCA in liquid medium. However, no detectable levels of 2,4,6-TCA production by this strain could be detected on cork when putative precursors other than 2,4,6-TCP, including several anisoles, dichlorophenols, trichlorophenols, or other highly chlorinated compounds, were tested. Time course expression studies with liquid cultures showed that the formation of 2,4,6-TCA was not affected by a high concentration of glucose (2% or 111 mM) or by ammonium salts at concentrations up to 60 mM. In T. longibrachiatum the O methylation of 2,4,6-TCP was catalyzed by a mycelium-associated S-adenosyl-l-methionine (SAM)-dependent methyltransferase that was strongly induced by 2,4,6-TCP. The reaction was inhibited by S-adenosyl-l-homocysteine, an inhibitor of SAM-dependent methylation, suggesting that SAM is the natural methyl donor. These findings increase our understanding of the mechanism underlying the origin of 2,4,6-TCA on cork, which is poorly understood despite its great economic importance for the wine industry, and they could also help us improve our knowledge about the biodegradation and detoxification processes associated with chlorinated phenols. PMID:12450804

  1. 25 CFR 1000.246 - Must an AFA that contains a construction project or activity incorporate provisions of Federal...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... as possible in the construction process. If Tribal construction standards are consistent with or... 25 Indians 2 2014-04-01 2014-04-01 false Must an AFA that contains a construction project or activity incorporate provisions of Federal construction standards? 1000.246 Section 1000.246 Indians...

  2. 25 CFR 1000.246 - Must an AFA that contains a construction project or activity incorporate provisions of Federal...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... as possible in the construction process. If Tribal construction standards are consistent with or... 25 Indians 2 2013-04-01 2013-04-01 false Must an AFA that contains a construction project or activity incorporate provisions of Federal construction standards? 1000.246 Section 1000.246 Indians...

  3. 25 CFR 1000.246 - Must an AFA that contains a construction project or activity incorporate provisions of Federal...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... as possible in the construction process. If Tribal construction standards are consistent with or... 25 Indians 2 2011-04-01 2011-04-01 false Must an AFA that contains a construction project or activity incorporate provisions of Federal construction standards? 1000.246 Section 1000.246 Indians...

  4. 25 CFR 1000.246 - Must an AFA that contains a construction project or activity incorporate provisions of Federal...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... as possible in the construction process. If Tribal construction standards are consistent with or... 25 Indians 2 2012-04-01 2012-04-01 false Must an AFA that contains a construction project or activity incorporate provisions of Federal construction standards? 1000.246 Section 1000.246 Indians...

  5. 48 CFR 246.404 - Government contract quality assurance for acquisitions at or below the simplified acquisition...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.404 Government contract quality assurance for acquisitions at or below the simplified acquisition threshold. Do not... quality assurance for acquisitions at or below the simplified acquisition threshold. 246.404 Section...

  6. SEDIMENT-MEDIATED REDUCTION OF 2,4,6-TRINITROTOLUENE AND FATE OF THE RESULTING AROMATIC (POLY)AMINES

    EPA Science Inventory

    2,4,6-Trinitrotoluene is a major surface and subsurface contaminant found at numerous munitions production and storage facilities. The reductive transformation of 2,4,6-trinitrotoluene (TNT) to aromatic (poly)amines and the consequent fate of these products were studied in anaer...

  7. APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations.

    PubMed

    Shen, Jinfeng; van den Bogaard, Ellen H; Kouwenhoven, Evelyn N; Bykov, Vladimir J N; Rinne, Tuula; Zhang, Qiang; Tjabringa, Geuranne S; Gilissen, Christian; van Heeringen, Simon J; Schalkwijk, Joost; van Bokhoven, Hans; Wiman, Klas G; Zhou, Huiqing

    2013-02-01

    p53 and p63 share extensive sequence and structure homology. p53 is frequently mutated in cancer, whereas mutations in p63 cause developmental disorders manifested in ectodermal dysplasia, limb defects, and orofacial clefting. We have established primary adult skin keratinocytes from ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome patients with p63 mutations as an in vitro human model to study the disease mechanism in the skin of EEC patients. We show that these patient keratinocytes cultured either in submerged 2D cultures or in 3D skin equivalents have impaired epidermal differentiation and stratification. Treatment of these patient keratinocytes with the mutant p53-targeting compound APR-246/PRIMA-1(MET) (p53 reactivation and induction of massive apoptosis) that has been successfully tested in a phase I/II clinical trial in cancer patients partially but consistently rescued morphological features and gene expression during epidermal stratification in both 2D and 3D models. This rescue coincides with restoration of p63 target-gene expression. Our data show that EEC patient keratinocytes with p63 mutations can be used for characterization of the abnormal molecular circuitry in patient skin and may open possibilities for the design of novel pharmacological treatment strategies for patients with mutant p63-associated developmental abnormalities. PMID:23355676

  8. 8 CFR 246.4 - Immigration judge's authority; withdrawal and substitution.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Immigration judge's authority; withdrawal... IMMIGRATION REGULATIONS RESCISSION OF ADJUSTMENT OF STATUS § 246.4 Immigration judge's authority; withdrawal and substitution. In any proceeding conducted under this part, the immigration judge shall...

  9. 8 CFR 246.4 - Immigration judge's authority; withdrawal and substitution.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Immigration judge's authority; withdrawal... IMMIGRATION REGULATIONS RESCISSION OF ADJUSTMENT OF STATUS § 246.4 Immigration judge's authority; withdrawal and substitution. In any proceeding conducted under this part, the immigration judge shall...

  10. 8 CFR 246.4 - Immigration judge's authority; withdrawal and substitution.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Immigration judge's authority; withdrawal... IMMIGRATION REGULATIONS RESCISSION OF ADJUSTMENT OF STATUS § 246.4 Immigration judge's authority; withdrawal and substitution. In any proceeding conducted under this part, the immigration judge shall...

  11. 8 CFR 246.4 - Immigration judge's authority; withdrawal and substitution.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Immigration judge's authority; withdrawal... IMMIGRATION REGULATIONS RESCISSION OF ADJUSTMENT OF STATUS § 246.4 Immigration judge's authority; withdrawal and substitution. In any proceeding conducted under this part, the immigration judge shall...

  12. 8 CFR 246.4 - Immigration judge's authority; withdrawal and substitution.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Immigration judge's authority; withdrawal... IMMIGRATION REGULATIONS RESCISSION OF ADJUSTMENT OF STATUS § 246.4 Immigration judge's authority; withdrawal and substitution. In any proceeding conducted under this part, the immigration judge shall...

  13. 40 CFR 246.201-3 - Recommended procedures: Glass, can, and mixed paper separation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Recommended procedures: Glass, can... and Recommended Procedures § 246.201-3 Recommended procedures: Glass, can, and mixed paper separation. In areas where markets are available, it is recommended that glass, cans, and mixed paper...

  14. 40 CFR 246.201-3 - Recommended procedures: Glass, can, and mixed paper separation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Recommended procedures: Glass, can... and Recommended Procedures § 246.201-3 Recommended procedures: Glass, can, and mixed paper separation. In areas where markets are available, it is recommended that glass, cans, and mixed paper...

  15. 40 CFR 246.201-3 - Recommended procedures: Glass, can, and mixed paper separation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Recommended procedures: Glass, can... and Recommended Procedures § 246.201-3 Recommended procedures: Glass, can, and mixed paper separation. In areas where markets are available, it is recommended that glass, cans, and mixed paper...

  16. 40 CFR 246.201-3 - Recommended procedures: Glass, can, and mixed paper separation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Recommended procedures: Glass, can, and... Recommended Procedures § 246.201-3 Recommended procedures: Glass, can, and mixed paper separation. In areas where markets are available, it is recommended that glass, cans, and mixed paper be separated at...

  17. 40 CFR 246.201-3 - Recommended procedures: Glass, can, and mixed paper separation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Glass, can... and Recommended Procedures § 246.201-3 Recommended procedures: Glass, can, and mixed paper separation. In areas where markets are available, it is recommended that glass, cans, and mixed paper...

  18. 40 CFR 721.10279 - Multi-walled carbon nanotubes (generic) (P-10-246).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Multi-walled carbon nanotubes (generic) (P-10-246). 721.10279 Section 721.10279 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES Significant New Uses for Specific Chemical Substances §...

  19. 48 CFR 52.246-7 - Inspection of Research and Development-Fixed-Price.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Inspection of Research and... Clauses 52.246-7 Inspection of Research and Development—Fixed-Price. As prescribed in 46.307(a), insert the following clause: Inspection of Research and Development—Fixed-Price (AUG 1996) (a) The...

  20. 48 CFR 52.246-8 - Inspection of Research and Development-Cost-Reimbursement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Inspection of Research and... Provisions and Clauses 52.246-8 Inspection of Research and Development—Cost-Reimbursement. As prescribed in 46.308, insert the following clause in solicitations and contracts for research and development...

  1. 48 CFR 52.246-7 - Inspection of Research and Development-Fixed-Price.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Inspection of Research and... Clauses 52.246-7 Inspection of Research and Development—Fixed-Price. As prescribed in 46.307(a), insert the following clause: Inspection of Research and Development—Fixed-Price (AUG 1996) (a) The...

  2. 48 CFR 52.246-7 - Inspection of Research and Development-Fixed-Price.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Inspection of Research and... Clauses 52.246-7 Inspection of Research and Development—Fixed-Price. As prescribed in 46.307(a), insert the following clause: Inspection of Research and Development—Fixed-Price (AUG 1996) (a) The...

  3. 48 CFR 52.246-8 - Inspection of Research and Development-Cost-Reimbursement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Inspection of Research and... Provisions and Clauses 52.246-8 Inspection of Research and Development—Cost-Reimbursement. As prescribed in 46.308, insert the following clause in solicitations and contracts for research and development...

  4. 48 CFR 52.246-7 - Inspection of Research and Development-Fixed-Price.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Inspection of Research and... Clauses 52.246-7 Inspection of Research and Development—Fixed-Price. As prescribed in 46.307(a), insert the following clause: Inspection of Research and Development—Fixed-Price (AUG 1996) (a) The...

  5. 40 CFR 246.200-4 - Recommended procedures: Levels of separation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Recommended procedures: Levels of... § 246.200-4 Recommended procedures: Levels of separation. A two-level separation is recommended for most... separate category cost effective may choose to implement three levels of separation: (1) Computer...

  6. SAGE ANALYSIS OF TRANSCRIPTOME RESPONSES IN ARABIDOPSIS ROOTS EXPOSED TO 2,4,6-TRINITROTOLUENE

    EPA Science Inventory

    Serial Analysis of Gene Expression (SAGE) was used to profile transcript levels in Arabidopsis thaliana roots and assess their responses to 2,4,6-trinitrotoluene (TNT) exposure. SAGE libraries representing control and TNT-exposed seedling root transcripts were constructed, and ea...

  7. 48 CFR 1852.246-71 - Government contract quality assurance functions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Government contract quality... Provisions and Clauses 1852.246-71 Government contract quality assurance functions. As prescribed in 1846.470, insert the following clause: Government Contract Quality Assurance Functions (OCT 1988) In...

  8. 32 CFR Appendix C to Part 246 - Personnel Policies and Procedures

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... employees, the S&S civilian personnel shall abide by 32 CFR part 40, the Department of Defense, the Unified... employment and include responsibilities, such as those in 32 CFR part 40, so that the S&S civilian employees... (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. C...

  9. 32 CFR Appendix C to Part 246 - Personnel Policies and Procedures

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... employees, the S&S civilian personnel shall abide by 32 CFR part 40, the Department of Defense, the Unified... employment and include responsibilities, such as those in 32 CFR part 40, so that the S&S civilian employees... (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. C...

  10. 32 CFR Appendix C to Part 246 - Personnel Policies and Procedures

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... employees, the S&S civilian personnel shall abide by 32 CFR part 40, the Department of Defense, the Unified... employment and include responsibilities, such as those in 32 CFR part 40, so that the S&S civilian employees... (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. C...

  11. 32 CFR Appendix C to Part 246 - Personnel Policies and Procedures

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... employees, the S&S civilian personnel shall abide by 32 CFR part 40, the Department of Defense, the Unified... employment and include responsibilities, such as those in 32 CFR part 40, so that the S&S civilian employees... (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. C...

  12. 48 CFR 52.246-7 - Inspection of Research and Development-Fixed-Price.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Inspection of Research and... Clauses 52.246-7 Inspection of Research and Development—Fixed-Price. As prescribed in 46.307(a), insert the following clause: Inspection of Research and Development—Fixed-Price (AUG 1996) (a) The...

  13. Florida School Laws. Chapters 228-246 Florida Statutes. 1998 Edition.

    ERIC Educational Resources Information Center

    Florida State Dept. of Education, Tallahassee.

    This volume of Florida School Laws contains chapters 228 through 246 of the Florida Statutes, which comprise "The Florida School Code." The laws contain those statutes specifically applicable to public schools, community colleges, postsecondary institutions, all other institutions and agencies included as a part of the state system of education,…

  14. Credit BG. View looks west southwest (246°) at surviving concrete ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. View looks west southwest (246°) at surviving concrete foundation for Utility Shop (T20). Building 4318 (Warehouse) appears at right of view. Reels contain electrical and fiber optic cables for installation at various sites at Edwards Air Force Base - Edwards Air Force Base, North Base, Utility Shop Pad T-20, Near C & First Streets, Boron, Kern County, CA

  15. 24 CFR 246.12 - Preemption of prospective term of lease.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Preemption of prospective term of... AUTHORITIES LOCAL RENT CONTROL Unsubsidized Insured Projects § 246.12 Preemption of prospective term of lease... new income levels, HUD preemption of prospective lease terms shall be effective for those new...

  16. 48 CFR 52.246-8 - Inspection of Research and Development-Cost-Reimbursement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Inspection of Research and... Provisions and Clauses 52.246-8 Inspection of Research and Development—Cost-Reimbursement. As prescribed in 46.308, insert the following clause in solicitations and contracts for research and development...

  17. 47 CFR 1.246 - Admission of facts and genuineness of documents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Admission of facts and genuineness of documents... PROCEDURE Hearing Proceedings Prehearing Procedures § 1.246 Admission of facts and genuineness of documents... request or of the truth of any relevant matters of fact set forth in the request. (b) Each of the...

  18. 47 CFR 1.246 - Admission of facts and genuineness of documents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Admission of facts and genuineness of documents... PROCEDURE Hearing Proceedings Prehearing Procedures § 1.246 Admission of facts and genuineness of documents... request or of the truth of any relevant matters of fact set forth in the request. (b) Each of the...

  19. 47 CFR 1.246 - Admission of facts and genuineness of documents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Admission of facts and genuineness of documents... PROCEDURE Hearing Proceedings Prehearing Procedures § 1.246 Admission of facts and genuineness of documents... request or of the truth of any relevant matters of fact set forth in the request. (b) Each of the...

  20. 47 CFR 1.246 - Admission of facts and genuineness of documents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Admission of facts and genuineness of documents... PROCEDURE Hearing Proceedings Prehearing Procedures § 1.246 Admission of facts and genuineness of documents... request or of the truth of any relevant matters of fact set forth in the request. (b) Each of the...

  1. 47 CFR 1.246 - Admission of facts and genuineness of documents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Admission of facts and genuineness of documents... PROCEDURE Hearing Proceedings Prehearing Procedures § 1.246 Admission of facts and genuineness of documents... request or of the truth of any relevant matters of fact set forth in the request. (b) Each of the...

  2. SOIL REDUCES 2,4,6-TRINITROTOLUENE BIOAVAILABILITY AND GENOTOXICITY IN VIVO

    EPA Science Inventory

    Soil Reduces 2,4,6- Trinitrotoluene Bioavailability and Genotoxicity In Vivo

    As chemicals age in soil, irreversible binding of chemical contaminants to organic components in the soil may occur, impacting the amount of chemical that is biologically available upon exp...

  3. Credit BG. View looks southwest (246°) across Small Arms Range. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. View looks southwest (246°) across Small Arms Range. Structure at extreme left is Building 4493 (Gymnasium), located in the secured area around Building 4505 - Edwards Air Force Base, North Base, Small Arms Range, Northeast of A Street, Boron, Kern County, CA

  4. 5 CFR 531.246 - Within-grade increases for GM employees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Within-grade increases for GM employees... REGULATIONS PAY UNDER THE GENERAL SCHEDULE Determining Rate of Basic Pay Special Rules for Gm Employees § 531.246 Within-grade increases for GM employees. GM employees are entitled to within-grade increases...

  5. 27 CFR 19.246 - Computing the effective tax rate for a product.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Computing the effective... Spirits Taxes Effective Tax Rates § 19.246 Computing the effective tax rate for a product. (a) How to compute effective tax rates. In order to determine the effective tax rate for a distilled spirits...

  6. 27 CFR 19.246 - Computing the effective tax rate for a product.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Computing the effective... Spirits Taxes Effective Tax Rates § 19.246 Computing the effective tax rate for a product. (a) How to compute effective tax rates. In order to determine the effective tax rate for a distilled spirits...

  7. 27 CFR 19.246 - Computing the effective tax rate for a product.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Computing the effective... Spirits Taxes Effective Tax Rates § 19.246 Computing the effective tax rate for a product. (a) How to compute effective tax rates. In order to determine the effective tax rate for a distilled spirits...

  8. 27 CFR 19.246 - Computing the effective tax rate for a product.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Computing the effective... Spirits Taxes Effective Tax Rates § 19.246 Computing the effective tax rate for a product. (a) How to compute effective tax rates. In order to determine the effective tax rate for a distilled spirits...

  9. 48 CFR 246.701 - Definitions as used in this subpart.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Definitions as used in... as used in this subpart. Acceptance as used in this subpart and in the warranty clauses at FAR 52.246.... Defect means any condition or characteristic in any supply or service furnished by the contractor...

  10. 48 CFR 246.701 - Definitions as used in this subpart.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Definitions as used in... as used in this subpart. Acceptance as used in this subpart and in the warranty clauses at FAR 52.246.... Defect means any condition or characteristic in any supply or service furnished by the contractor...

  11. 48 CFR 246.701 - Definitions as used in this subpart.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Definitions as used in... as used in this subpart. Acceptance as used in this subpart and in the warranty clauses at FAR 52.246.... Defect means any condition or characteristic in any supply or service furnished by the contractor...

  12. Preparation of 1,3,5-triamino-2,4,6-trinitrobenzene of submicron particle size

    DOEpatents

    Rigdon, Lester P.; Moody, Gordon L.; McGuire, Raymond R.

    2001-01-01

    A method is disclosed for the preparation of very small particle size, relatively pure 1,3,5-triamino-2,4,6-trinitrobenzene (TATB). Particles of TATB prepared according to the disclosed method are of submicron size and have a surface area in the range from about 3.8 to 27 square meters per gram.

  13. Preparation of 1,3,5-triamo-2,4,6-trinitrobenzene of submicron particle size

    DOEpatents

    Rigdon, Lester P.; Moody, Gordon L.; McGuire, Raymond R.

    2001-05-01

    A method is disclosed for the preparation of very small particle size, relatively pure 1,3,5-triamino-2,4,6-trinitrobenzene (TATB). Particles of TATB prepared according to the disclosed method are of submicron size and have a surface area in the range from about 3.8 to 27 square meters per gram.

  14. TOXICITY OF TETRYL (N-METHYL-N,2,4,6-TETRANITROANILINE) IN F344 RATS

    EPA Science Inventory

    The toxicity of tetryl (N-methyl-N,2,4,6-tetranitroaniline) in male and female F344 rats was evaluated after adminstration in the diet for 14 or 90 days. The 14-day study diet concentrations used were 0, 500, 1250, 2000, 2500, and 5000 ppm; the 90-day study diet concentrations we...

  15. 42 CFR 137.246 - How does a Self-Governance Tribe retrocede a PSFA?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false How does a Self-Governance Tribe retrocede a PSFA... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.246 How does a Self-Governance Tribe retrocede a PSFA? The Self-Governance Tribe submits a...

  16. 42 CFR 137.246 - How does a Self-Governance Tribe retrocede a PSFA?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false How does a Self-Governance Tribe retrocede a PSFA... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.246 How does a Self-Governance Tribe retrocede a PSFA? The Self-Governance Tribe submits a...

  17. 42 CFR 137.246 - How does a Self-Governance Tribe retrocede a PSFA?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false How does a Self-Governance Tribe retrocede a PSFA... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.246 How does a Self-Governance Tribe retrocede a PSFA? The Self-Governance Tribe submits a...

  18. 42 CFR 137.246 - How does a Self-Governance Tribe retrocede a PSFA?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false How does a Self-Governance Tribe retrocede a PSFA... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.246 How does a Self-Governance Tribe retrocede a PSFA? The Self-Governance Tribe submits a...

  19. 42 CFR 137.246 - How does a Self-Governance Tribe retrocede a PSFA?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How does a Self-Governance Tribe retrocede a PSFA... INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.246 How does a Self-Governance Tribe retrocede a PSFA? The Self-Governance Tribe submits a...

  20. Toxicological characterization of 2,4,6-trinitrotoluene, its transformation products, and two nitramine explosives.

    PubMed

    Neuwoehner, Judith; Schofer, Andrea; Erlenkaemper, Bibiane; Steinbach, Klaus; Hund-Rinke, T Kerstin; Eisentraeger, Adolf

    2007-06-01

    The soil and groundwater of former ordnance plants and their dumping sites have often been highly contaminated with the explosive 2,4,6-trinitrotoluene (2,4,6-TNT) leading to a potential hazard for humans and the environment. Further hazards can arise from metabolites of transformation, by-products of the manufacturing process, or incomplete combustion. This work examines the toxicity of polar nitro compounds relative to their parent compound 2,4,6-TNT using four different ecotoxicological bioassays (algae growth inhibition test, daphnids immobilization test, luminescence inhibition test, and cell growth inhibition test), three genotoxicological assays (umu test, NM2009 test, and SOS Chromotest), and the Ames fluctuation test for detection of mutagenicity. For this study, substances typical for certain steps of degradation/transformation of 2,4,6-TNT were chosen for investigation. This work determines that the parent compounds 2,4,6-TNT and 1,3,5-trinitrobenzene are the most toxic substances followed by 3,5-dinitrophenol, 3,5-dinitroaniline and 4-amino-2-nitrotoluene. Less toxic are the direct degradation products of 2,4,6-TNT like 2,4-dinitrotoluene, 2,6-dinitrotoluene, 2-amino-4,6-dinitrotoluene, and 4-amino-2,6-dinitrotoluene. A weak toxic potential was observed for 2,4,6-trinitrobenzoic acid, 2,4-diamino-6-nitrotoluene, 2,4-dinitrotoluene-5-sulfonic acid, and 2,6-diamino-4-nitrotoluene. Octahydro-l,3,5,7-tetranitro-l,3,5,7-tetrazocine and hexahydro-1,3,5-trinitro-l,3,5-triazine show no hint of acute toxicity. Based on the results of this study, we recommend expanding future monitoring programs of not only the parent substances but also potential metabolites based on conditions at the contaminated sites and to use bioassays as tools for estimating the toxicological potential directly by testing environmental samples. Site-specific protocols should be developed. If hazardous substances are found in relevant concentrations, action should be taken to prevent

  1. Project Plan Remote Target Fabrication Refurbishment Project

    SciTech Connect

    Bell, Gary L; Taylor, Robin D

    2009-08-01

    authorization for the work was received in July 2009 under the Remote Target Fabrication Refurbishment Task of the Enhanced Utilization of Isotope Facilities project (Project Identification Code 2005230) funded by the American Recovery and Reinvestment Act of 2009. The goal of this project is to recover the capability to produce 4-5 curium targets for the irradiation period starting with HFIR cycle 427, currently scheduled to begin 2/17/10. Assuming success, the equipment would then be used to fabricate 6-7 additional targets to hold for the next irradiation campaign specified by the program. Specific objectives are the return to functionality of the Cubicle 3 Pellet Fabrication Line; Cubicle 2 Target Assembly equipment; and Cubicle 1 Target Inspection and Final Assembly system.

  2. White upconversion luminescence nanocrystals for the simultaneous and selective detection of 2,4,6-trinitrotoluene and 2,4,6-trinitrophenol.

    PubMed

    Ma, Yingxin; Huang, Sheng; Deng, Mingliang; Wang, Leyu

    2014-05-28

    A highly water stable and strong upconversion (UC) luminescence NaYF4@PSI-NH nanosensor for the simultaneous and selective detection of 2,4,6-trinitrotoluene (TNT) and 2,4,6-trinitrophenol (TNP) was successfully developed. Via the 980 nm near-infrared (NIR) irradiation, these nanosensors emit strong white UC luminescence with five typical emission peaks centered at 363, 455, 475, 546, and 654 nm. The UC emission at both 363 and 546 nm was quenched by the addition of TNT; however, the ratio of luminescence intensity at 363 nm to 546 nm (I363/I546) had no change with the increase of TNT concentration. Meanwhile, only violet UC emission at 363 nm was dramatically quenched via the addition of TNP, and the I363/I546 ratio is negatively proportional to the TNP concentration in the range of 0.01-4.5 μg/mL of TNP. On the other hand, the green UC emission intensity at 546 nm is in negative proportion to the concentration of TNT. Moreover, cyclohexane, toluene, and other nitroaromatics (such as 2,4-dinitrotoluene (DNT) and nitrobenzene (NB)) have no influence on the detection. Therefore, we developed a facile method for the simultaneous and selective detection of TNT and TNP in the mixture solution of nitroaromatics independent of complicated instruments and sample pretreatment. PMID:24734988

  3. Theoretical design of energetic nitrogen-rich derivatives of 1,7-diamino-1,7-dinitrimino-2,4,6-trinitro-2,4,6-triazaheptane.

    PubMed

    Wu, Qiong; Zhu, Weihua; Xiao, Heming

    2013-08-01

    The heats of formation (HOFs), energetic properties, and thermal stability of a series of 1,7-diamino-1,7-dinitrimino-2,4,6-trinitro-2,4,6-triazaheptane derivatives with different substituents, different numbers of substituents, and different original chains are found by using the DFT-B3LYP method. The results show that -NO2 or -NH2 is an effective substituent for increasing the gas-phase HOFs of the title compounds, especially -NO2 group. As the numbers of substitutents increase, their HOFs enhance obviously. Increasing the length of original chain is helpful for improving their HOFs. The substitution of -NO2 is useful for enhancing their detonation performances and the effects of the length of original chains on detonation properties are coupled with those of the substituents. An analysis of the BDE of the weakest bonds indicates that the substitution of the -NH2 groups and replacing the -NO2 groups of N-NO2 by the -NH2 groups are favorable for improving their thermal stability, while the substitution of -NO2 and increasing the length of original chain decrease their thermal stability. Considering the detonation performance and thermal stability, seven compounds may be considered as the potential candidates of high energy density compounds. PMID:23559097

  4. Vicarious nucleophilic substitution to prepare 1,3-diamino-2,4,6-trinitrobenzene or 1,3,5-triamino-2,4,6-trinitrobenzene

    DOEpatents

    Mitchell, A.R.; Pagoria, P.F.; Schmidt, R.D.

    1996-10-29

    The present invention relates to a process to produce 1,3-diamino-2,4,6-trinitrobenzene (DATB) or 1,3,5-triamino-2,4,6,trinitrobenzene (TATB) by: (a) reacting at ambient pressure and a temperature of between about 0 and 50 C for between about 0.1 and 24 hr, a trinitroaromatic compound of the structure shown within where X, Y, and Z are each independently selected from --H, or --NH{sub 2}, with the proviso that at least 1 or 2 of X, Y, and Z are hydrogen, with an amount effective to produce DATB or TATB, or 1,1,1-trialkylhydrazinium halide wherein alkyl is selected from methyl, ethyl, propyl or butyl and halide is selected from chloride, bromide or iodide, in the presence of a strong base selected from sodium butoxide, potassium butoxide, potassium propoxide, sodium propoxide, sodium ethoxide, potassium ethoxide, sodium methoxide, potassium methoxide, and combinations thereof; in a solvent selected from the group consisting of methanol, ethanol, propanol, butanol, dimethylsulfoxide, N-methylpyrrolidone, hexamethylphosphoramide, dimethylformide, dimethylacetamide and mixtures thereof, provided that when alcohols are present primarily DATB and picramide is formed; and (b) isolating the DATB or TATB produced. DATB and TATB are useful specialty explosives. TATB is also used for the preparation of benzenehexamine, a starting material for the synthesis of novel materials (optical imaging devices, liquid crystals, ferromagnetic compounds).

  5. Vicarious nucleophilic substitution to prepare 1,3-diamino-2,4,6-trinitrobenzene or 1,3,5-triamino-2,4,6-trinitrobenzene

    DOEpatents

    Mitchell, Alexander R.; Pagoria, Philip F.; Schmidt, Robert D.

    1996-01-01

    The present invention relates to a process to produce 1,3-diamino-2,4,6-trinitrobenzene (DATB) or 1,3,5-triamino-2,4,6,-trinitrobenzene (TATB) by: (a) reacting at ambient pressure and a temperature of between about 0.degree. and 50.degree. C. for between about 0.1 and 24 hr, a trinitroaromatic compound of structure V: ##STR1## wherein X, Y, and Z are each independently selected from --H, or --NH.sub.2, with the proviso that at least 1 or 2 of X, Y, and Z are hydrogen, with an amount effective to produce DATB or TATB of 1,1,1-trialkylhydrazinium halide wherein alkyl is selected from methyl, ethyl, propyl or butyl and halide is selected from chloride, bromide or iodide. in the presence of a strong base selected from sodium butoxide, potassium butoxide, potassium propoxide, sodium propoxide, sodium ethoxide, potassium ethoxide, sodium methoxide, potassium methoxide, and combinations thereof; in a solvent selected from the group consisting of methanol, ethanol, propanol, butanol, dimethylsulphoxide, N-methylpyrrolidone, hexamethylphosphoramide, dimethylformide, dimethylacetamide and mixtures thereof, provided that when alcohols are present primarily DATB and picramide is formed; and (b) isolating the DATB or TATB produced. DATB and TATB are useful specialty explosives. TATB is also used for the preparation of benzenehexamine, a starting material for the synthesis of novel materials (optical imaging devices, liquid crystals, ferromagnetic compounds).

  6. Quantitative SERS detection of low-concentration aromatic polychlorinated biphenyl-77 and 2,4,6-trinitrotoluene.

    PubMed

    Bao, Zhi Yong; Liu, Xin; Chen, Y; Wu, Yucheng; Chan, Helen L W; Dai, Jiyan; Lei, Dang Yuan

    2014-09-15

    This paper reports a simple label-free high-sensitive method for detecting low-concentration persistent organic pollutants and explosive materials. The proposed method combines surface-enhanced Raman spectroscopy (SERS) and magnetomotive enrichment of the target molecules on the surface of Ag nanoparticles (NPs). This structure can be achieved through self-assembling integration of Ag NPs with ferromagnetic Fe3O4 microspheres, forming a hybrid SERS nanoprobe with both optical and magnetic properties. Moreover, the magnetic response of ferromagnetic Fe3O4 microspheres can be used to dynamically modulate the optical property of Ag NPs through controlling their geometric arrangement on the substrate by applying an external magnetic field. It is also demonstrated from the full-wave numerical simulation results that the maximum electromagnetic field enhancement can be greatly increased by shortening the distance of neighboring Ag NPs and therefore resulting in an improved SERS detecting limit. More importantly, by using the prepared substrate, the SERS signals from organic pollution substances, i.e. aromatic polychlorinated biphenyl-77 and 2,4,6-trinitrotoluene, were quantitatively analyzed. PMID:25232653

  7. Extraction-less, rapid assay for the direct detection of 2,4,6-trichloroanisole (TCA) in cork samples.

    PubMed

    Apostolou, Theofylaktos; Pascual, Nuria; Marco, M-Pilar; Moschos, Anastassios; Petropoulos, Anastassios; Kaltsas, Grigoris; Kintzios, Spyridon

    2014-07-01

    2,4,6-trichloroanisole (TCA), the cork taint molecule, has been the target of several analytical approaches over the few past years. In spite of the development of highly efficient and sensitive tools for its detection, ranging from advanced chromatography to biosensor-based techniques, a practical breakthrough for routine cork screening purposes has not yet been realized, in part due to the requirement of a lengthy extraction of TCA in organic solvents, mostly 12% ethanol and the high detectability required. In the present report, we present a modification of a previously reported biosensor system based on the measurement of the electric response of cultured fibroblast cells membrane-engineered with the pAb78 TCA-specific antibody. Samples were prepared by macerating cork tissue and mixing it directly with the cellular biorecognition elements, without any intervening extraction process. By using this novel approach, we were able to detect TCA in just five minutes at extremely low concentrations (down to 0.2 ppt). The novel biosensor offers a number of practical benefits, including a very considerable reduction in the total assay time by one day, and a full portability, enabling its direct employment for on-site, high throughput screening of cork in the field and production facilities, without requiring any type of supporting infrastructure. PMID:24840453

  8. Decreased transpiration in poplar trees exposed to 2,4,6-trinitrotoluene

    SciTech Connect

    Thompson, P.L.; Ramer, L.A.; Guffey, A.P.; Schnoor, J.L.

    1998-01-01

    The improper handling of the toxic compound 2,4,6-trinitrotoluene (TNT) has led to the contamination of soil and groundwater, and the uptake of TNT by a variety of plants has been established. This article discusses the effects of various concentrations of the explosive 2,4,6-trinitrotoluene (TNT) on the transpiration of hybrid poplar trees growing in hydroponic media. Transpiration was measured daily by gravimetric means. The rapid removal of TNT from hydroponic solutions was a result of plant uptake and required a daily dosage of TNT to ensure a relatively constant exposure over time. Transpiration decreased with increasing TNT concentrations {ge}5 mg/L. Decreases in transpiration were accompanied by leaf chlorosis and abscission. A comparison between a laboratory study and a pilot-scale experiment showed good scale-up potential.

  9. Spot test for 1,3,5-triamino-2,4,6-trinitrobenzene, TATB

    DOEpatents

    Harris, B.W.

    1984-11-29

    A simple, sensitive and specific spot test for 1,3,5-triamino-2,4,6-trinitrobenzene, TATB, is described. Upon the application of the composition of matter of the subject invention to samples containing in excess of 0.1 mg of this explosive, a bright orange color results. Interfering species such as TNT and Tetryl can be removed by first treating the sample with a solvent which does not dissolve the TATB, but readily dissolves these interfering explosives.

  10. Spot test for 1,3,5-triamino-2,4,6-trinitrobenzene, TATB

    DOEpatents

    Harris, Betty W.

    1986-01-01

    A simple, sensitive and specific spot test for 1,3,5-triamino-2,4,6-trinitrobenzene, TATB, is described. Upon the application of the composition of matter of the present invention to samples containing in excess of 0.1 mg of this explosive, a bright orange color results. Interfering species such as TNT and Tetryl can be removed by first treating the sample with a solvent which does not dissolve much of the TATB, but readily dissolves these explosives.

  11. 2,4,6-Trichloroanisole is a potent suppressor of olfactory signal transduction

    PubMed Central

    Takeuchi, Hiroko; Kato, Hiroyuki; Kurahashi, Takashi

    2013-01-01

    We investigated the sensitivity of single olfactory receptor cells to 2,4,6-trichloroanisole (TCA), a compound known for causing cork taint in wines. Such off-flavors have been thought to originate from unpleasant odor qualities evoked by contaminants. However, we here show that TCA attenuates olfactory transduction by suppressing cyclic nucleotide-gated channels, without evoking odorant responses. Surprisingly, suppression was observed even at extremely low (i.e., attomolar) TCA concentrations. The high sensitivity to TCA was associated with temporal integration of the suppression effect. We confirmed that potent suppression by TCA and similar compounds was correlated with their lipophilicity, as quantified by the partition coefficient at octanol/water boundary (pH 7.4), suggesting that channel suppression is mediated by a partitioning of TCA into the lipid bilayer of plasma membranes. The rank order of suppression matched human recognition of off-flavors: TCA equivalent to 2,4,6-tribromoanisole, which is much greater than 2,4,6-trichlorophenol. Furthermore, TCA was detected in a wide variety of foods and beverages surveyed for odor losses. Our findings demonstrate a potential molecular mechanism for the reduction of flavor. PMID:24043819

  12. Development of the small-molecule antiviral ST-246® as a smallpox therapeutic

    PubMed Central

    Grosenbach, Douglas W; Jordan, Robert; Hruby, Dennis E

    2011-01-01

    Naturally occurring smallpox has been eradicated, yet it remains as one of the highest priority pathogens due to its potential as a biological weapon. The majority of the US population would be vulnerable in a smallpox outbreak. SIGA Technologies, Inc. has responded to the call of the US government to develop and supply to the Strategic National Stockpile a smallpox antiviral to be deployed in the event of a smallpox outbreak. ST-246® (tecovirimat) was initially identified via a high-throughput screen in 2002, and in the ensuing years, our drug-development activities have spanned in vitro analysis, preclinical safety, pharmacokinetics and efficacy testing (all according to the ‘animal rule’). Additionally, SIGA has conducted Phase I and II clinical trials to evaluate the safety, tolerability and pharmacokinetics of ST-246, bringing us to our current late stage of clinical development. This article reviews the need for a smallpox therapeutic and our experience in developing ST-246, and provides perspective on the role of a smallpox antiviral during a smallpox public health emergency. PMID:21837250

  13. p53 Reactivation by PRIMA-1(Met) (APR-246) sensitises (V600E/K)BRAF melanoma to vemurafenib.

    PubMed

    Krayem, Mohammad; Journe, Fabrice; Wiedig, Murielle; Morandini, Renato; Najem, Ahmad; Salès, François; van Kempen, Leon C; Sibille, Catherine; Awada, Ahmad; Marine, Jean-Christophe; Ghanem, Ghanem

    2016-03-01

    Intrinsic and acquired resistance of metastatic melanoma to (V600E/K)BRAF and/or MEK inhibitors, which is often caused by activation of the PI3K/AKT survival pathway, represents a major clinical challenge. Given that p53 is capable of antagonising PI3K/AKT activation we hypothesised that pharmacological restoration of p53 activity may increase the sensitivity of BRAF-mutant melanoma to MAPK-targeted therapy and eventually delay and/or prevent acquisition of drug resistance. To test this possibility we exposed a panel of vemurafenib-sensitive and resistant (innate and acquired) (V600E/K)BRAF melanomas to a (V600E/K)BRAF inhibitor (vemurafenib) alone or in combination with a direct p53 activator (PRIMA-1(Met)/APR-246). Strikingly, PRIMA-1(Met) synergised with vemurafenib to induce apoptosis and suppress proliferation of (V600E/K)BRAF melanoma cells in vitro and to inhibit tumour growth in vivo. Importantly, this drug combination decreased the viability of both vemurafenib-sensitive and resistant melanoma cells irrespectively of the TP53 status. Notably, p53 reactivation was invariably accompanied by PI3K/AKT pathway inhibition, the activity of which was found as a dominant resistance mechanism to BRAF inhibition in our lines. From all various combinatorial modalities tested, targeting the MAPK and PI3K signalling pathways through p53 reactivation or not, the PRIMA-1(Met)/vemurafenib combination was the most cytotoxic. We conclude that PRIMA-1(Met) through its ability to directly reactivate p53 regardless of the mechanism causing its deactivation, and thereby dampen PI3K signalling, sensitises (V600E/K)BRAF-positive melanoma to BRAF inhibitors. PMID:26790143

  14. Biotransformation of 2,4,6-trinitrotoluene in Anabaena sp. cultures

    SciTech Connect

    Pavlostathis, S.G.; Jackson, G.H.

    1999-03-01

    The transformation of 2,4,6-trinitrotoluene (TNT) was investigated in cultures of the cyanobacterium Anabaena sp. by conducting a series of batch assays. 2,4,6-Trinitrotoluene was added to Anabaena sp. cultures in single and consecutive additions, at various initial concentrations, to determine its transformation kinetics, to identify products formed, to evaluate potential toxicity, and to determine the effect of light deprivation on the TNT transformation process. 2,4,6-Trinitrotoluene disappearance occurred only in the presence of Anabaena sp. cultures maintained under a normal 16-h photoperiod. Toxicity leading to culture chlorosis and death was observed in batch systems with an initial TNT concentration greater than 10 mg/L. A low rate and extent of TNT disappearance was observed in light-deprived cultures, which were inhibited even at low TNT concentrations. At pH values between 7.5 and 8.5, azoxy-tetranitrotoluene isomers were detected in both the culture medium and solvent extracts of biomass and accounted for only 20 and 4.4% of the initially added TNT moles, respectively. At a culture pH range between 5.6 and 5.9, achieved by aeration with a 5% CO{sub 2}/air mixture, hydroxylaminodinitrotoluene equimolar to the TNT addition was produced and then depleted from the culture medium with prolonged incubation. Although TNT reduction in Anabaena sp. cultures occurred, yielding low levels of azoxy-tetranitrotoluene isomers or hydroxylaminodinitrotoluene, uptake and other transformation reactions of TNT and/or its transformation products by Anabaena sp. may have taken place. Based on a less than 15% observed increase of biomass concentration over the relatively short incubation periods and by considering the mean biomass concentration constant, the TNT disappearance rate followed pseudo-first-order kinetics. The biomass carbon-normalized TNT disappearance rates in Anabaena sp. cultures were about three orders of magnitude higher than previously reported TNT

  15. Impact of ST-246® on ACAM2000™ smallpox vaccine reactogenicity, immunogenicity, and protective efficacy in immunodeficient mice

    PubMed Central

    Berhanu, Aklile; King, David S.; Mosier, Stacie; Jordan, Robert; Jones, Kevin F.; Hruby, Dennis E.; Grosenbach, Douglas W.

    2010-01-01

    Although a highly effective vaccine against smallpox, vaccinia virus (VV) is not without adverse events, some of which can be life-threatening, particularly in immunocompromised individuals. We have recently demonstrated that the immunogenicity and protective efficacy of Dryvax® in immunocompetent mice is preserved even when co-administered with ST-246, an orally bioavailable small-molecule inhibitor of orthopoxvirus egress and dissemination. In addition, ST-246 markedly reduced the reactogenicity of the smallpox vaccine ACAM2000 and the highly neurovirulent VV strain Western Reserve (VV-WR). Here, we evaluated the impact of ST-246 co-administration on ACAM2000 reactogenicity, immunogenicity, and protective efficacy in seven murine models of varying degrees of humoral and cellular immunodeficiency: BALB/c and B-cell deficient (JH-KO) mice depleted of CD4+ or CD8+ or both subsets of T cells. We observed that ST-246 reduced vaccine lesion severity and time to complete resolution in all of the immunodeficient models examined, except in those lacking both CD4+ and CD8+ T cells. Although VV-specific humoral responses were moderately reduced by ST-246 treatment, cellular responses were generally comparable or slightly enhanced at both 1 and 6 months post-vaccination. Most importantly, in those models in which vaccination given alone conferred protection against lethal VV challenge, similar levels of protection were observed at both time points when vaccination was given with ST-246. These data suggest that, with the exception of individuals with irreversible, combined CD4+ and CD8+ T-cell deficiency, ST-246 co-administered at the time of vaccination may help reduce vaccine reactogenicity –even in those lacking humoral immunity– without impeding the induction of protective immunity. PMID:21036130

  16. Chemical stability of molten 2,4,6-trinitrotoluene at high pressure

    NASA Astrophysics Data System (ADS)

    Dattelbaum, Dana M.; Chellappa, Raja S.; Bowden, Patrick R.; Coe, Joshua D.; Margevicius, Madeline A.

    2014-01-01

    2,4,6-trinitrotoluene (TNT) is a molecular explosive that exhibits chemical stability in the molten phase at ambient pressure. A combination of visual, spectroscopic, and structural (x-ray diffraction) methods coupled to high pressure, resistively heated diamond anvil cells was used to determine the melt and decomposition boundaries to >15 GPa. The chemical stability of molten TNT was found to be limited, existing in a small domain of pressure-temperature conditions below 2 GPa. Decomposition dominates the phase diagram at high temperatures beyond 6 GPa. From the calculated bulk temperature rise, we conclude that it is unlikely that TNT melts on its principal Hugoniot.

  17. UV photolysis for enhanced phenol biodegradation in the presence of 2,4,6-trichlorophenol (TCP).

    PubMed

    Song, Jiaxiu; Wang, Wenbing; Li, Rongjie; Zhu, Jun; Zhang, Yongming; Liu, Rui; Rittmann, Bruce E

    2016-02-01

    A bacterial strain isolated from activated sludge and identified as Bacillus amyloliquefaciens could biodegrade phenol, but 2,4,6-trichlorophenol (TCP) inhibited phenol biodegradation and biomass growth. UV photolysis converted TCP into dichlorocatechol, monochlorophenol, and dichlorophenol, and this relieved inhibition by TCP. Phenol-removal and biomass-growth rates were significantly accelerated after UV photolysis: the monod maximum specific growth rate (μ(max)) increased by 9% after TCP photolysis, and the half-maximum-rate concentration (K(S)) decreased by 36%. Thus, the major benefit of UV photolysis in this case was to transform TCP into a set of much-less-inhibitory products. PMID:26747251

  18. Toxicity and mutagenicity of 2,4,-6-trinitrotoluene and its microbial metabolites.

    PubMed Central

    Won, W D; DiSalvo, L H; Ng, J

    1976-01-01

    TNT (2,4,6-trinitrotoluene) of explosive grade is highly toxic to marine forms that included fresh water unicellular green algae (Selenastrum capricornutum), tidepool copepods (Tigriopus californicus), and oyster larvae (Crassostrea gigas), and mutagenic to Salmonella typhimurium. On the basis of mutagenic assays carried out with a set of histidine-requiring strains of the bacterium, TNT was detected as a frameshift mutagen that significantly accelerates the reversion rate of a frameshift tester, TA-98. In contrast, the major microbial metabolites of TNT appeared to be nontoxic and nonmutagenic. Images PMID:773306

  19. Fermi LAT Detection of a Gamma-ray Flare from the BL Lac Object ON 246

    NASA Astrophysics Data System (ADS)

    Becerra, Josefa

    2015-06-01

    The Large Area Telescope (LAT) on board the Fermi Gamma-ray Space Telescope has observed increasing gamma-ray flux from a source positionally consistent with the BL Lac object ON 246 (RA=187.55871 deg, Dec=25.30198 deg, J2000, Beasley et al. 2002, ApJS, 141, 13; with redshift z=0.135, Nass et al. 1996, A&A, 309, 419), also known as S3 1227+25 and 3FGL J1230.3+2519 (3FGL; Acero et al. 2015, arXiv:1501.02003).

  20. Factors affecting 2,4,6-trinitrotoluene degradation in contaminated soil

    SciTech Connect

    Bradley, P.M.; Chapelle, F.H.

    1995-12-31

    Recent microcosm studies at an inactive ordnance works at Weldon Spring, Missouri indicated that the indigenous microorganisms are capable of complete transformation oaf 2,4,6-trinitrotoluene (TNT) within approximately 22 days. However, the continuing presence of TNT at the Weldon Spring site suggests that some combination of environmental factors is inhibiting microbial degradation at the site. This paper briefly summarizes the results of investigations of the effects of carbon substrate availability, soil moisture content, TNT concentration, and oxygen condition on TNT degradation by the microorganisms indigenous to Weldon Spring.