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  1. [DR ALEKSANDAR DORŠNER THE FIRST HOSPITAL OTORHINOLARYNGOLOGIST IN SPLIT AND DALMATIA].

    PubMed

    Ivanišević, Petar; Poljak, Nikola Kolja; Cikojević, Draško; Doršner, Katarina; Ivanišević, Milan

    2015-01-01

    Dr Aleksandar Doršner (Trebinje, 1892 - Lima, 1967) was the first hospital otorhinolaryngologist in Split and Dalmatia. He graduated from the Faculty of Medicine in Prague in 1919, and specialized otorhinolaryngology in Graz and Vienna. He led and organized otorhinolaryngological service in Split Hospital from 1923 to 1934, and he also had a private practice. Temporarily he also worked outside Split in Dalmatian hinterland and in Šibenik, Zadar and Dubrovnik. Most frequently he performed the following otorhinolaryngological operations: tonsillectomies and adenoidectomies and operations of purulent middle ear inflammations with mastoiditis, nasal polyps, deviated nasal septum, maxillary sinus empyema and otorhinolaryngological trauma. In 1928 he became a member of Otorhinolaryngological section of Croatian Medical Chamber. He participated in the work of the first otorhinolaryngological congress of the former Yugoslavia in 1931, taken place in Zagreb. From 1928 he was a member of Oto-Neuro-Ophthalmological Society. From 1933 to 1937 he was a vice-president of the main board of Free Organization of Dalmatian Physicians in Split. In 1938 he left Split permanently and continued living with his family in Lima (Peru) where he died in 1967. He was an erudite. He lived for his profession which he liked very much and dedicated his life to. He is one of the most meritorious doctors in Split medical history, whom otorhinolaryngology service in Split Hospital started with. PMID:26502677

  2. Revolutionary changes in medicine and ophthalmology--the St. Louis, MO, effect: Homer G. Phillips Hospital and Dr. Howard Phillip venable.

    PubMed Central

    Johnson, Andrew S.

    2003-01-01

    PURPOSE: To provide information on the revolutionary changes in medicine, particularly on the development of African-Americans in ophthalmology, created by Homer G. Phillips Hospital in St. Louis and the late Dr. Howard Phillip Venable. METHODS: Very little has been written about Homer G. Phillips Hospital and Dr. H. Phillip Venable. Through personal interviews with physicians trained by Dr. Venable and literature review, I was able to obtain information on Homer G. Phillips Hospital and Dr. Venable's influence in breaking the color line in medicine and ophthalmology. RESULTS: Homer G. Phillips Hospital in St. Louis was a major teaching hospital for African-American doctors. Dr. Venable was one of a few African-American ophthalmologists in the 1940s. Dr. Venable then trained approximately 40 African-American ophthalmologists at Homer G. Phillips Hospital between 1943 to 1979, when the hospital closed. CONCLUSION: The ophthalmologists trained by Dr. Venable have gone forward to treat thousands of patients with blinding eye diseases such as glaucoma and diabetes, and to influence others to become ophthalmologists. Although the hospital has closed and Dr. Venable has passed away, their existence has reformed the medical treatment received by African-Americans and other people. Images p484-a PMID:12856914

  3. Dr Walter Henry Anderson (1870-1937) and the mission hospital at Safed, Palestine.

    PubMed

    Stokes, Gordon S

    2013-02-01

    Walter Henry Anderson, a brewer's clerk in Burton-upon-Trent, became a missionary doctor, supported by a society promoting welfare and evangelism in Jewish communities abroad. His family background was rich in pastoral ministry at home and adventure abroad. Arguably, this background played a part in his decision to serve the Jews of Safed. His life in Palestine entailed much enterprise and hardship as he raised a family, fought disease and set up a mission hospital serving not only the Jewish community but persons of all faiths. His years in Palestine, from 1894 to 1915, were times of peace in the Middle East before the turmoil unleashed by the Great War. Jews from the Diaspora were gaining an increasing foothold in Palestine, their 'Promised Land'. Themes of that era - the rise of Zionism, confrontation between Judaism and evangelical Christianity, conflict between immigrant Jew and Palestinian Arab and the remarkable travels of Lawrence of Arabia were interwoven with the lives of Dr Anderson and his family. PMID:23610230

  4. Decreased Monocyte HLA-DR Expression in Patients After Non-Shockable out-of-Hospital Cardiac Arrest.

    PubMed

    Venet, Fabienne; Cour, Martin; Demaret, Julie; Monneret, Guillaume; Argaud, Laurent

    2016-07-01

    Out-of-hospital cardiac arrest (OHCA) constitutes a major health care problem with the development in immediate survivors of a post-cardiac arrest syndrome including systemic inflammatory response as observed in sepsis. As a decreased monocyte HLA-DR expression (mHLA-DR) has been repeatedly described in septic patients in association with an increased risk of death and nosocomial infections, we tested whether this immune alteration could also be observed after OHCA. Fifty-five non-shockable OHCA patients sampled at Day 0 (D0: within 4 h after OHCA), D1 (the next day), and D3: (after 2 additional days) were included. CD4+ lymphocyte count and mHLA-DR were evaluated by flow cytometry. We observed a marked decrease in mHLA-DR as early as D0 in patients compared with normal values. This decrease persisted till D3 and was associated with a moderate decrease in the number of circulating CD4+ lymphocytes. No correlations were identified between mHLA-DR and usual prognostic markers after OHCA. However, overtime evolution in mHLA-DR values appeared different between survivors and non-survivors with a quasisystematic decrease between D1 and D3 in non-survivors versus an increased expression in survivors. In conclusion, this preliminary pilot study describes the occurrence of OHCA-induced immune alterations as illustrated by a decreased mHLA-DR and CD4+ lymphopenia. Furthermore, we show for the first time the differential overtime evolution in mHLA-DR between survivors and non-survivors without association with usual prognostic markers and multiple organ failure. These initial results should now be confirmed in a larger cohort of OHCA patients. PMID:26796574

  5. Evaluation of Nosocomial Infection in Patients at hematology-oncology ward of Dr. Sheikh children’s hospital

    PubMed Central

    Ghassemi, A; Farhangi, H; Badiee, Z; Banihashem, A; Mosaddegh, MR

    2015-01-01

    Background Infections in critical care unit are high, and they are serious hospital problems. Infections acquired during the hospital stay are generally called nosocomial infections, initially known as infections arising after 48 h of hospital admission. The mostfrequent nosocomial infections (urinary, respiratory, gastroenteritis and blood stream infection) were common in patients at hospital.The aim was to study, the current status of nosocomial infection, rate of infection among hospitalized children at hematology-oncology ward of Dr. Sheikh children’s hospital, Mashhad, Iran. Materials and Methods Data were collected from 200 patient's records presented with symptoms of nosocomial infection at hematology-oncology ward of Dr. Sheikh children’s hospital from March 2014 to September 2014. Descriptive statistics using percentage was calculated. Results Incidence of nosocomial infections inpatients athematology-oncology ward was 31% (62/200). Of which 69.35% (43/62) blood stream infection being the most frequent; followed by 30.64% (19/62) was urinary tract infection (UTI), and the most common blood culture isolate was been Staphylococcus epidermidis 18 (41.86%), andour study showed that large numbers ofnosocomial UTIs causing by Gram‑negative bacteria. Conclusion This study showed blood stream infection and UTI are the common nosocomial infections among patients athematology-oncology ward. Early recognition of infections and short term use of invasive devices along with proper infection control procedures can significantly decrease the incidence of nosocomial infections in patients. PMID:26985350

  6. [Tuberculous meningitis: a 10-year analysis at the "Dr. Federico Gómez" Children's Hospital of Mexico].

    PubMed

    Karam Bechara, J; Sosa, R; Naime Libien, J E; Posada Maldonado, E E

    1991-01-01

    Of all the forms of tuberculous infection in children, the most frequent is the pulmonary, but the tuberculous meningitis is the most severe and mortal, it occurs mainly in children under five years old, and the highest mortality is in children under two. The results of a retrospective study carried out at the Children Hospital of Mexico "Dr. Federico Gómez" about all the patients hospitalized with tuberculous meningitis diagnose during the January 1975 to December 1985 period were presented. One hundred and eighteen cases were studied: the majority (80%) corresponded to children under four years old, a percentage of 79 presented some degree of malnutrition, and 86 per cent showed clinical data of neurological affection. The confirmation of the diagnose was made in the majority of cases through laboratory and cabinet studies. Forty per cent showed no alteration in the chest X-rays, and the isolation of the bacillus was in a very low percentage (15%). All the patients were treated with the antituberculous drugs mentioned, with a better development in the ones associated with steroids. The hospital stay was over 30 days in 15 per cent of the cases. The mortality of the series reviewed was 44.5 per cent. PMID:2047934

  7. The characteristics of HIV and AIDS patients with deep vein thrombosis at Dr. George Mukhari Academic Hospital

    PubMed Central

    Mabuza, Honey L.; Ogunbanjo, Gboyega A.

    2015-01-01

    Background Deep vein thrombosis (DVT) is 10 times more prevalent in HIV and AIDS patients than in the general population and is more common in patients with severe immune suppression (CD4 < 200 cells/mL). Opportunistic infections render HIV and AIDS patients susceptible to a hypercoaguable state, including lower protein S levels. Aim and setting To present the profile of HIV and AIDS patients who developed DVT in the primary care wards of Dr. George Mukhari Academic Hospital (DGMAH), Garankuwa. Methods Cross-sectional study of clinical records of admitted HIV and AIDS patients without DVT to the primary care wards, DGMAH, from 01 February 2010 to 31 January 2011. Results Two hundred and twenty-nine patients were admitted and 17 (7.4%) developed DVT. Of those that developed DVT, eight (47%) had infection with tuberculosis (TB), four (24%) had pneumonia and four (24%) had gastroenteritis. The risk of developing DVT was 8/94 (8.5%) in those with TB, 4/53 (7.5%) in those with gastroenteritis and 4/75 (5.3%) in those with pneumonia. The mean duration of stay was 14.1 days in those with DVT versus 4.0 days in those without. Conclusion HIV (and AIDS) is a hypercoaguable state and the risk of DVT is relatively high in patients with opportunistic infections. HIV and AIDS patients who are admitted to hospital with opportunistic infections may benefit from anti-thrombotic prophylaxis and further studies are needed to evaluate this. PMID:26245588

  8. Prognosis of tetanus patients in the intensive care unit of Provincial Hospital Jason Sendwe, Lubumbashi, DR Congo

    PubMed Central

    Muteya, Michel Manika; Kabey, Alain Kabey a; Lubanga, Théophile Muyumba; Tshamba, Henri Mundongo; Nkoy, Albert Mwembo Tambwe a

    2013-01-01

    Tetanus is still a public health problem in developing countries including the Democratic Republic of Congo. The objective of this study was to determine the prognosis of patients with tetanus admitted in the Intensive Care Unit (ICU) of Provincial Hospital Jason Sendwe, Lubumbashi, DR Congo. This is a descriptive study which collected information from registers and medical records of patients admitted for tetanus in the ICU of Jason Sendwe Hospital, between January 2005 and December 2009. We calculated the parameters of position, dispersion as well as frequencies. We used the test of independent association of prognosis (death versus survival). Tetanus constituted 2.1% of admissions in the ICU during the 5-year period. The average age of patients was 39.38 ± 17; majority of patients were males (95.5%). The majority of patients lived the townships of Kampemba (27.3%), Kenya (22.7%), and Annexe (18.2%). All patients presented the generalized form of the infection. The door of entry was detectable in 71.5% of cases, localized mainly to the lower limbs (61.9%). The average length of stay was 11.29 ± 11.39 days. Mortality was observed in 52.4% of cases. This mortality was statistically significant in patients aged mrore than 40 years (p=0.029) but not not related to the length of stay (p=0.080) nor the location of point of entry(p=0.28). In our environment the prognosis of tetanus remains severe. This disease is still frequent in the city of Lubumbashi; sensibilisation of population on preventive strategies as well as setting up appropriate structures for better management of cases is required. PMID:23717709

  9. Association between Severe Dehydration in Rotavirus Diarrhea and Exclusive Breastfeeding among Infants at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

    PubMed Central

    Prasetyo, Dwi; Sabaroedin, Iesje Martiza; Ermaya, Yudith Setiati; Soenarto, Yati

    2015-01-01

    Background. Rotavirus is the leading cause of severe acute diarrhea in children. Infants who are exclusively breastfed develop fewer infections and have less severe illnesses. This study aimed to determine association between severe dehydration in rotavirus diarrhea and exclusive breastfeeding. Methods. This is a cross-sectional study in infants ≤ 6 months old with acute diarrhea in Dr. Hasan Sadikin Hospital, Bandung, Indonesia. Results. From 134 infants ≤ 6 months old with acute diarrhea enrolled from April 2009 to December 2012, there were 88 (65.6%) boys and 46 (34.4%) girls in this study. Rotavirus was detected in 60 (44.8 %), 32 (53.3%) of whom were exclusively breastfed. From rotavirus positive subjects, severe dehydration occurred in 4 (12.6%) exclusively breastfed infants and 6 (21.5%) not exclusively breastfed infants. No significant association was found between severe dehydration and exclusive breastfeeding (p = 0.491) in rotavirus diarrhea. Conclusions. In rotavirus diarrhea, there was no significant association between exclusive breastfeeding and severe dehydration. PMID:26612990

  10. Stevens-Johnson syndrome and toxic epidermal necrolysis in Dr. Hasan Sadikin General Hospital Bandung, Indonesia from 2009-2013

    PubMed Central

    Suwarsa, Oki; Dharmadji, Hartati Purbo; Sutedja, Endang

    2016-01-01

    Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions (SCAR) with high mortality and have a significant public health impact because of high mortality and morbidity. Objective To describe data the epidemiological features, etiology, and treatment of retrospectively reviewed data of all patients with SJS and TEN. Methods Retrospective study was conducted in patients with SJS and TEN treated from January 1, 2009 to December 31, 2013 in Dr. Hasan Sadikin General Hospital Bandung, Indonesia. Results A total of 57 patients were enrolled in the study. Thirty-nine cases of SJS (21 males and 18 females), 7 cases of SJS overlapping TEN (4 males and 3 females), and 11 cases of TEN (5 males and 6 females) were reported. All cases of SJS and TEN were caused by drugs, such as paracetamol (16.56%), carbamazepine (7%), amoxicillin (5.73%), ibuprofen (4.46%), rifampicin (3.18%), and trihexyphenidyl (3.18%). All cases were treated systemically with corticosteroid alone (100%). Seven from 57 patients (12,28%) died; 5 cases developed sepsis and 2 cases developed respiratory failure. The mortality rate was 7.69% in SJS, 0% in SJS/TEN overlap, and 36.36% in TEN. Conclusion The role of systemic corticosteroids in SJS and TEN are still controversial, but with a prompt and earlier treatment reduces mortality and improves outcomes of SJS and TEN patients. PMID:26844219

  11. The protestant medical missions to China: Dr Thomas Richardson Colledge (1796-1879) and the founding of the Macao Ophthalmic Hospital.

    PubMed

    Fu, Louis

    2013-05-01

    A surgeon of the British East India Company, Dr Thomas Richardson Colledge, founded the Macao Ophthalmic Hospital in 1827. This was not only the first Western hospital ever opened in China for the purpose of bringing modern medicine to the Chinese but also the precursor of similar efforts of later medical missions in China. The gratifying results of this institute proved that employing Western medicine was an effective way to introduce Christianity to China and to open her door to the outside world. Though not a missionary himself, Colledge is rightfully regarded as the originator of medical missionaries to China. PMID:24585752

  12. PREVALENCE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS FROM NOSE AND THROAT OF PATIENTS ON ADMISSION TO MEDICAL WARDS OF DR SOETOMO HOSPITAL, SURABAYA, INDONESIA.

    PubMed

    Kuntaman, K; Hadi, Usman; Setiawan, Firman; Koendori, Eko Budi; Rusli, Musofa; Santosaningsih, Dewi; Severin, Juliette; Verbrugh, Henri A

    2016-01-01

    Epidemiological data of methicillin resistant Staphylococcus aureus (MRSA) carriage in Indonesian hospitals are still scarce. These data are required for health management of infectious diseases in order to control hospital MRSA. The carriage rate of MRSA in nose and throat of patients on admission to Dr Soetomo Hospital Surabaya, Indonesia was 8.1% of 643 patients, 5.4% from throat, 3.9% from nose and 1.2% from both sites. Prevalence of MRSA among patients admitted to surgical and non-surgical ward was not different (8.2% and 8.0%, respectively). Although MRSA prevalence in Indonesian hospitals is low compared to many other countries worldwide, appropriate health strategies will be needed to be implemented if this infection is to be controlled. PMID:27086426

  13. Specificity of 136 patient's antibodies to human red blood cells in Dr. Max Peralta J Hospital Blood Bank 2004-February 2009.

    PubMed

    Cerdas-Quesada, César

    2010-04-01

    The development of alloantibodies and erythrocyte autoantibodies complicates transfusion therapy. The antibodies detection of potential clinical significance in 136 samples of Dr. Max Peralta J Hospital Blood Bank patients, Cartago, Costa Rica between 2004 and February, 2009 were evaluated. Transfusion of phenotypically matched blood for Rh and Kell systems proved to be effective in preventing alloimmunization because it been found in this study that there is good evidence that a high proportion of antibodies produced in response to transfusion are Rh and K specificity. PMID:20100667

  14. Cost of hospital care for HIV/AIDS infected patients in three general reference hospitals in Lubumbashi, DR Congo: prospective cohort study

    PubMed Central

    Tshamba, Henri Mundongo; a Kaut, Clarence Mukeng; Kyalubile, Nono Mulubwa; Kakambal, Alphonse Kaij; Yav, Grevisse Ditend; Kaj, Françoise Malonga; Vancaillie, Didier

    2013-01-01

    Introduction This article analyses the composition of healthcare costs for HIV/AIDS infected patients in a country with limited resources and attempts to identify the factors that influence these costs. The aims are to calculate medical care costs, analysing how they vary depending on patients’ income, and to evaluate the factors explaining healthcare consumption. Methods This is a prospective cohort study focusing on patients who were admitted to hospital for a short stay between January 2010 and June 2011, before their integration into a specialised program. The patients were selected randomly. Free consent was obtained from all participants. Data were analysed using the SPSS 19.0 software. The significance threshold was set at 5% and the CI (Confidence Interval) at 95%. We used Kruskal-Wallis tests, Fisher's exact test and multiple linear regression. Results We monitored 209 patients. Their average age was 36.37 years (SD: 8.72). The sex ratio was 0.58 and the women patients were generally younger than the male ones (p=0.011). The overall cost of healthcare amounted to $US 41,922. The cost of Antiretroviral Therapy represented 21.6% ($US 9,045). The price of para-clinical examinations represented 46% ($US 19,136) of the overall cost. The patient's average monthly income was $US 157.40 whereas the average direct cost per patient was$US 201.45. Both monthly income (t=4.385; p=0.0000) and education level (t=3.703 p=0.0003) were statistically significant predictive factors for healthcare consumption. The medical care costs for patients with opportunistic infections were nine times higher than those for patients who presented none. The presence of opportunistic infections increased healthcare consumption by approximately 31$ US (CI 95%: 15-46.9). Conclusion The average direct cost for patients on each short-term stay was higher than the average monthly income. To be able to access the necessary services, the patients need additional resources, which are derived

  15. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher von Braun with Dr. Eberhard Rees and R.W. Cook at a press conference concerning Dr. Von Braun's assignment to NASA headquarters and Dr. Rees' subsequent assignment as Marshall Center director.

  16. Dr. Wernher Von Braun with Dr. Christian Barnard.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Christian Barnard Tours Marshall Space Flight Center. Shown in Dr. Von Braun's office are (left to right): Dr. Ernst Sthulinger, a representative from General Electric, Dr. Wernher Von Braun, Dr. Christian Barnard, and Dr. Eberhard Rees.

  17. CONHECIMENTO DA LEI GERAL DE SAÚDE – RESPEITO ÀS TRANSFUSÕES SANGUÍNEAS EM MÉDICOS E PACIENTES TESTEMUNHAS DE JEOVÁ DO HOSPITAL DR. DARÍO CONTRERAS DA REPÚBLICA DOMINICANA

    PubMed Central

    SANTANA, ELSA DÍAZ

    2010-01-01

    Este estudo avalia quanto o corpo médico do Hospital Dr. Darío Contreras de República Dominicana conhece, respeita, informa e aplica a Lei Geral de Saúde em relação aos direitos do paciente Testemunha de Jeová de negar-se a ser transfundido (respeito a sua autonomia); também se os Testemunhas de Jeová conhecem a Lei Geral de Saúde e até que ponto têm se beneficiado diante dessa proposição. O estudo revelou que nem médicos, nem Testemunhas de Jeová conhecem de fato essa lei. PMID:20689657

  18. Large Customers (DR Sellers)

    SciTech Connect

    Kiliccot, Sila

    2011-10-25

    State of the large customers for demand response integration of solar and wind into electric grid; openADR; CAISO; DR as a pseudo generation; commercial and industrial DR strategies; California regulations

  19. ["Del governo tecnico sanitario degli Ospedali" (Italian) ("Hospital governance") by E. Ronzani (1877-1943)- Padua (Italy), 1910].

    PubMed

    Renzulli, Lorenzo

    2014-01-01

    This article describes the contents of the first edition of the Italian textbook "Del governo tecnico sanitario degli ospedali" ("Hospital Governance") written by Prof. Enrico Ronzani (1877- 1943) and published in Padua (Italy) in 1910. The textbook contains a a preface by Prof. A. Serafini. Prof. Ronzani, a lecturer in Hygiene and health in 1910, introduced the first university course in "Hygiene and hospital technique" in Italy, in Padua in the academic year 1910-1911. The book focuses principally on the duties and responsibilities inherent in the role of the medical director. PMID:24770366

  20. Afebrile pneumonia (whooping cough) syndrome in infants at Hospital Universitario del Valle, Cali, 2001-2007

    PubMed Central

    Villegas, Dolly; Echandía-Villegas, Connie Alejandra

    2012-01-01

    Introduction: Afebrile pneumonia syndrome in infants, also called infant pneumonitis, pneumonia caused by atypical pathogens or whooping cough syndrome is a major cause of severe lower respiratory infection in young infants, both in developing countries and in developed countries. Objective: To describe children with afebrile pneumonia syndrome. Methods: Through a cross-sectional study, we reviewed the medical records of children diagnosed with afebrile pneumonia treated at Hospital Universitario del Valle, a reference center in southwestern Colombia, between June 2001 and December 2007. We obtained data on maternal age and origin, prenatal care, the childs birth, breastfeeding, vaccination status, symptoms, signs, diagnosis, treatment, and complications. Results: We evaluated 101 children with this entity, noting a stationary presentation: June-August and November- December. A total of 73% of the children were under 4 months of age; the most common symptoms were: cyanotic and spasmodic cough (100%), respiratory distress (70%), and unquantified fever (68%). The most common findings: rales (crackles) (50%), wheezing and expiratory stridor (37%); 66% were classified as mild and of the remaining 33%, half of them required attention in the intensive care unit. In all, there was clinical diagnosis of afebrile pneumonia syndrome in infants, but no etiologic diagnosis was made and despite this, 94% of the children received macrolides. Conclusions: These data support the hypothesis that most of these patients acquired the disease by airway, possibly caused by viral infection and did not require the indiscriminate use of macrolides. PMID:24893051

  1. Dr. Barnett's dream

    SciTech Connect

    Wilson, A.

    1990-04-01

    In 1986, AstroPower was a tiny R D company located at the University of Delaware. Like many other entrepreneurs in the field at that time, the company's president, Dr. Allen Barnett, had a good idea, a good research staff, and the dream of becoming a successful manufacturer of photovoltaic (PV) cells. If the Newark, Del. company's projections remain on track, Barnett plans to become the third largest PV manufacturer in the United States by the end of next year. Were it not for the company's performance to date, such a claim might well be dismissed as idle dreaming. AstroPower Inc. is pursuing a two-pronged strategy: to rapidly bring a new thin-crystal silicon PV cell to commercialization; and, in the meantime, to gain experience in manufacturing and distributing conventional single-crystal and polycrystal silicon cells. The company sold approximately 200 kilowatts (kWp) of cells last year (about half single-crystal and half polycrystal). Its current production capacity is 360 kWp. The company and its products are described.

  2. [Influence of tobacco smoking on newborn's birth weight--analisys of dates concerning births from Maternity Hospital named. Dr S. Mossor's in Opole City].

    PubMed

    Guzikowski, Wojciech; Pirogowicz, Iwona

    2008-01-01

    Despite wide education, tobacco smoking while being pregnant is very important issue in perinatology. It is important problem because of life style of polish society, including pregnant women. Clinical observation of this issue is pointing on risk of occurring pathology in pregnancy, unfavorable consequences for neonate also many distant pathological effects among children. Purpose of this was getting an answer for question: whether in current social and economic situation there is connection between low birth mass and smoking tobacco during pregnancy. Under analysis were found births between 38th and 40th one hundred successive births (according to book of birth-room from 2860 labors in hospital in Opol, 2007) of mothers are smoking up to 10 cigarettes a day (group I), mothers smoking 11-20 cigarettes a day (group II) and mothers that are not smoking. This works affirms that smoking has negative influence on child birth mass. It is also displayed that higher the number of smoked cigarettes the higher percent of newborns with low birth mass and higher number o fetus with intrauterine growth retardation. Among mothers that are smoking the biggest group were young women (mean. 24, years) and multipara female (58%). PMID:19189515

  3. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Thomas Paine, Deputy Administrator of the National Aeronautics and Space Administration, examines an ordinary man's shoe outfitted for use in the Saturn I workshop. Pictured from the left in the Saturn I workshop mockup are William Brooksbank, propulsion and vehicle engineering laboratory; Dr. Paine; Dr. Wernher Von Braun, Marshall Center director; Colonel Clare F. Farley, Executive Officer in the Office Of The Administrator; and Charles J. Donlan, Deputy Associate Administrator for Manned Space Flight, Technical. the shoe Dr. Paine is holding has a unique fastener built into the sole to allow an astronaut to move about on the workshop floor and to remain in one position if he desires.

  4. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (left) and Fred W. Kelley examine a ST-100 Stellar Instrument Platform in the astrionics lab. Dr. Von Braun, then deputy associate administrator for planning, NASA, was visiting on the anniversary of the establishment of the Marshall Space Flight Center.

  5. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Shown viewing the Apollo telescope mockup are, from left to right, Charles Donlan, deputy associate administrator for manned space flight; Dr. Wernher Von Braun, Marshall Space Flight Center director; William Horton, astrionics lab; Dr. Thomas Paine, NASA deputy administrator; Warner Kuers, director of the ME lab.

  6. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1968-01-01

    Dr. Wernher Von Braun, stands in front of a Saturn IB Launch Vehicle at Kennedy Space Center (KSC). Dr. Von Braun was Marshall's first Center Director (1960-1970). Under his leadership Marshall was responsible for the development of the Saturn rockets, the Skylab project and getting the United States into Space and landing on the moon with the Apollo missions.

  7. Dr. Daniel Carter

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Dr. Daniel Carter, president of New Century Pharmaceuticals in Huntsville, Al, is one of three principal investigators in NASA's microgravity protein crystal growth program. Dr. Carter's experties is in albumins. Albumins are proteins in the bloodstream that transport materials, drugs, nutrients, and wastes. Photo credit: NASA/Marshall Space Flight Center

  8. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (right), Deputy Associate Administrator for planning, National Aeronautics and Space Administration, inspects the mockup of the Saturn Workshop during a visit marking the 10th anniversary of the Marshall Center. Shown with Dr. Von Braun, from left to right, are Karl Heimburg, Director of the astronautics lab; Herman K. Weidner, Director of Science and Engineering, and George Hardy of the Astronautics lab.

  9. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (right), Deputy Associate Administrator for Planning, National Aeronautics and Space Administration, inspects the mockup of the Saturn Workshop during a visit marking the 10th anniversary of the Marshall Center. Shown with Dr. Von Braun, from left to right, are Karl Heimburg, Director of the Astronautics Lab; Herman K. Weidner, Director of Science and Engineering, and George Hardy of the Astronautics Lab.

  10. Goldie Brangman Remembers the Operation to Save Dr King.

    PubMed

    Koch, Evan; Brangman, Goldie

    2015-12-01

    In September 1958 the Rev Dr Martin Luther King Jr was stabbed and nearly assassinated. Surgeons at Harlem Hospital in New York City removed a 17.8-cm (7-in)-long letter opener from Dr King's chest. Certified Registered Nurse Anesthetist Goldie Brangman remembers this event because she participated in Dr King's anesthetic. This article correlates Brangman's memories with published accounts of the event. It also places the event within the context of the modern civil rights movement that Dr King led. PMID:26742331

  11. Dr. Eberhard Rees

    NASA Technical Reports Server (NTRS)

    1970-01-01

    Dr. Eberhard Rees served as director of the Marshall Space Flight Center from March 1, 1970 until January 19, 1973 when he retired from NASA. Prior to his appointment as Director, Rees served as the Center's deputy director under Dr. Wernher von Braun, 1960-1970. Rees came to the United States as part of the Dr. Wernher von Braun's German Rocket team following World War II. He transferred to Huntsville, Alabama from Fort Bliss, Texas in 1950 to work for the Army's rocket program at Redstone Arsenal. From 1956 to 1960 he served as deputy director of development operations at the Army Ballistic Missile Agency under von Braun. In 1960 Rees was transferred to NASA's Marshall Center.

  12. Dr. Wernher von Braun

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Dr. von Braun is looking out from a 10th floor window of building 4200 at the Marshall Space Flight Center (MSFC). He was the first Center Director and served as the Director from July 1960 through February 1970. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under the Project Paperclip (American acquisition of German rocket experts) to continue their rocket development work. In 1950, von Braun and his German Rocket Team (also called the Peenemuende Team) were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center (MSFC). Under Dr. von Braun's leadership, MSFC developed the Saturn V launch vehicle, which placed the first men, two American astronauts, on the Moon. Wernher von Braun's life was dedicated to expanding man's knowledge through the exploration of space.

  13. Dr Pugh: a poisoner?

    PubMed

    Paull, J D; Morris, G M

    2012-07-01

    On 16 February 1845 the Reverend W. H. Browne, rector of St John's Church in Launceston, Van Diemen's Land, wrote in his journal, "My dear Wife died very suddenly almost immediately after and in consequence of taking a preparation of Hyd. Cyan. Acid prepared & supplied by Dr Pugh". This journal entry raises a number of questions. Was Dr Pugh treating a condition which he thought merited that treatment or was it a ghastly mistake? Was Caroline Browne suffering from pulmonary tuberculosis? Was hydrocyanic acid an accepted treatment at that time? Did Mrs Browne take the wrong dose? Was an incorrect concentration of the drug prepared by Dr Pugh? Did he use the wrong pharmacopoeia in preparing the hydrocyanic acid? Why was there no inquest? Only some of these questions can be answered. PMID:23230685

  14. 1. View of three detection radar (DR) antennas. DR 1 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View of three detection radar (DR) antennas. DR 1 (structure no. 735) on left, DR 2 (structure no. 736) in center, and DR 3 (structure no. 737) looking north 30 degrees west, with tracking radar (large radome) and satcom (satellite communication) system in small radome in view between DR 2 and DR 3 antennae. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  15. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1999-01-01

    A camerman catches Dr. Wernher Von Braun, Director of the Marshall Space Flight Center, his son, Peter, and daughter, Martgrit, as they arrive at the employee picnic held to celebrate man's first landing on the moon 6 days earlier. In the foreground is David R. Newby, Director of Administration and Technical Services at the Marshall Space Flight Center.

  16. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1968-01-01

    Dr. Wernher von Braun, Director of the Marshall Space Flight Center, explains the purpose of a thermal curtain in the mockup of a Saturn I workshop to U.S. Representative Armistead Seldon of Alabama. The Congressman visited the Marshall Center on March 2, 1968 to tour the workshop and to visit Marshall Center facilities.

  17. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1968-01-01

    U.S. Representative Armistead Seldon (D.-Al) inspects the food preparation area of the Saturn I workshop mockup during a visit to the Marshall Space Flight Center. Explaining the operation of the food preparation area to the congressman is Dr. Wernher Von Braun, Marshall Space Flight Center director.

  18. Ask Dr. Sue.

    ERIC Educational Resources Information Center

    Aronson, Susan S.

    1990-01-01

    Discusses the need for child care providers to be sure children in their care who are between the ages of 15 months and 5 years have had Haemophilus influenzae type b (Hib) vaccine. Urges child care center staff to avoid use of bean bag infant cushions and to inform parents about the hazards posed by the cushions. (DR)

  19. Dr. Goddard Transports Rocket

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Dr. Robert H. Goddard tows his rocket to the launching tower behind a Model A Ford truck, 15 miles northwest of Roswell, New Mexico. 1930- 1932. Dr. Goddard has been recognized as the 'Father of American Rocketry' and as one of three pioneers in the theoretical exploration of space. Robert Hutchings Goddard was born in Worcester, Massachusetts, on October 15, 1882. He was a theoretical scientist as well as a practical engineer. His dream was the conquest of the upper atmosphere and ultimately space through the use of rocket propulsion. Dr. Goddard, who died in 1945, was probably as responsible for the dawning of the Space Age as the Wright Brothers were for the begining of the Air Age. Yet his work attracted little serious attention during his lifetime. When the United States began to prepare for the conquest of space in the 1950's, American rocket scientists began to recognize the debt owed to the New England professor. They discovered that it was virtually impossible to construct a rocket or launch a satellite without acknowledging the work of Dr. Goddard. This great legacy was covered by more than 200 patents, many of which were issued after his death.

  20. Dr. Faustus: Theist or Atheist?

    ERIC Educational Resources Information Center

    Karim, Shah Mohammad Sanaul; Fathema, Fawzia; Hakim, Abdul

    2015-01-01

    Dr. Faustus is the greatest but the most controversial of Marlowe's plays. Among the causes of controversy, whether Dr. Faustus is an atheist or theist deserves utmost attention. This paper is intended to deal with the issue. Though at various stages of the development of the action, Dr. Faustus abjures Trinity, resorts to necromancy, becomes…

  1. Introduction of Dr. Andrew V Schally

    PubMed Central

    Mendoza-Valdés, Arturo

    2015-01-01

    I first met Dr. Andrew V Schally (PhD, MDhc (Multi), DSc, Distinguished Medical Research Scientist, U.S. Department of Veterans Affairs Professor of Pathology and Department of Medicine,
Miller School of Medicine, University of Miami, Miami, Florida, USA) many years ago, probably around the beginning of the 1990's in one of his visits to Mexico City (Figure 1). He has many friends in my country since some of the investigations that led to the development of the LHRH agonists were made in a couple of Mexican hospitals in collaboration with some outstanding Mexican physicians that I will mention later. In that time, I was the head of the Department of Urology of the Mexican National Cancer Institute and our Director, Dr. Jaime de la Garza, invited him for a meeting. I was surprised by his humbleness, intelligence and easy going personality, in spite of being a Nobel Prize scientist. PMID:26112485

  2. [Radiological percutaneous gastrostomy (GRP), 17 años de experiencia, serie de casos del hospital Universitario Virgen del Rocío].

    PubMed

    Navarro Falcón, Magnolia Del Carmen; Parejo Campos, Juana; Pereira Cunill, José Luis; García Luna, Pedro Pablo

    2015-01-01

    When assessing a patient nutritional support the state of the gastrointestinal tract is the most important point to consider, whenever possible we should choose the enteral nutrition (EN) over parenteral nutrition (PN) and recognized by its various advantages. The percutaneous gastrostomy (GRP) were introduced in clinical practice as an alternative to surgical gastrostomy (GQ). The speed, simplicity, low cost, low morbidity and low mortality of these techniques has allowed its rapid development.The feeding tubes types used were the balloon-retained devices catheter, the pig tail and the ballon-retained with gastropexia (gastropexia). It is a retrospective study of all patients who were placed GPR in the Virgen del Rocío University Hospital, Sevilla, between September 1996 and September 2013, which aims to study is to describe the characteristics of patients and the complications presented for different types of enteral feeding tubes used. GPR 186 were performed in 176 patients (135 males (76.70%), with an average duration of 303.6 days, the most frequent diseases were cancers of the head and neck 49.46%. The types of feeding tubes used were pigtail 118 (63.44%), balloon-retained devices 22 (11.83%), and gastropexia 46 (24.73%). The most common early complications in the pigtail group were early purulent exudate and early bleeding (2.5 and 3.4% respectively), while in the balloon catheter group the initial output of the probe was most frequent early complication (13.7%), none of these complications were observed in the group of gastropexy. The most common late complication was obstruction probe. The GPR is a safe technique with lower mortality of 1%; Low frequently of early and late complications. A better understanding of this technique can reduce the frequency of complications. PMID:25561125

  3. Dr. Wernher Von Braun

    NASA Technical Reports Server (NTRS)

    1960-01-01

    On September 8, 1960 President Dwight D. Eisenhower visited Huntsville, Alabama to dedicate a new NASA field center in honor of General George C. Marshall, Eisenhower's wartime colleague and the founder of the famous Marshall Plan for European recover after World War II. The new George C. Marshall Space Flight Center was placed under the control of Dr. Wernher Von Braun shown here talking with President Eisenhower. As parto f his remarks dedicating the center, President Eisenhowe refereed to General Marshall as a 'man of yar, yet a builder of peace'. the Marshall Center's first major assignment including building the huge Saturn V rocket that launched human beings on their first journey to the surface of the moon in 1969.

  4. Human radiation studies: Remembering the early years. Oral history of Dr. Nadine Foreman, M.D., August 19, 1994

    SciTech Connect

    1995-07-01

    Dr. Nadine Foreman was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). Dr. Foreman was selected for interview because of the position she held at the University of California, San Francisco. Following a brief biographical sketch, Dr. Foreman describes her work with Dr. Mayo Soley using I-131 in treatment of hyperthyroidism, selection criteria for patients in the radioiodine project, work with Dr. Earl Miller, work at Highland Hospital, radioiodine treatment of diffuse toxic goiter (myxedema), the radiophosphorus and radioiodine programs with Dr. Bert Low-Beer, and treatment of polycythemia vera.

  5. Dr. Hugh Dryden Swearing in Dr. George E. Mueller

    NASA Technical Reports Server (NTRS)

    1963-01-01

    Dr. George E. Mueller being sworn in, as Associate Administrator for the Office of Manned Space Flight for NASA, by Dr. Hugh L. Dryden NASAs Deputy Administrator. The ceremony took place at NASA HQ in Washington, DC on September 3, 1963. Mueller served as Associate Administrator from 1963 to 1969, where he was responsible for overseeing the completion of Project Apollo and for beginning the development of the Space Shuttle.

  6. 5. View of middle DR 2 antenna with DR 1 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. View of middle DR 2 antenna with DR 1 antenna in background. Photograph shows on left side at bottom foundation berm and along right side bottom stanchion concrete foundations at bottom structural steel assembly. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  7. 42 CFR 415.162 - Determining payment for physician services furnished to beneficiaries in teaching hospitals.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... exceed $30,000. Example No: 2. Dr. Smith received $25,000 from Hospital X for services as a department head in a teaching hospital. Dr. Smith also voluntarily furnished direct medical services to... compensated services ($25,000) exceeds the $30,000 maximum amount allowable for all of Dr. Smith's...

  8. Wally Schirra Greets Dr. Wernher von Braun

    NASA Technical Reports Server (NTRS)

    1968-01-01

    Apollo 7 Commander Walter M. Schirra, Jr., left, greets Dr. Wernher Von Braun, Director, Marshall Space Flight Center and Dr. Kurt Debus, Right, KSC Director, during a prelaunch mission briefing held at the Florida Spaceport.

  9. [Prevention of hepatitis B--HLA DR/DQ in HBs Ag nonresponder].

    PubMed

    Ouchi, E; Hoshino, A; Miura, T; Nagahara, N; Kudo, Y; Tamura, M

    1989-11-01

    To evaluate the immunological background in HBs Ag nonresponders against hepatitis B vaccine, the lymphocyte surface marker and HLA-DR/DQ antigen were determined on hospital personnel, 70 males and 256 females, injected hepatitis B vaccine for three times. The vaccine made from the plasma of HBs Ag carriers was injected at the first and second vaccination and recombinant hepatitis B vaccine was injected at the third vaccination. A month after the third vaccination, blood was withdrawn for HBs antigen test by RIA. Border line cases (cut off index 1.0-1.9) are included in nonresponder (cut off index less than 0.9). Both nonresponders and low responders (cut off index 2-49) are more often seen in males than females and high responder (cut off index 50 or more) are seen more often in young females than males. Lymphocyte surface markers were studied by flow cytometry using the following monoclonal antibodies; OKT 3, 4, 8, DR, NK, Ia 1 and B7. No differences between lymphocyte surface markers of nonresponders and responders were noted. HLA-DR/DQ antigens were studied by the cytotoxicity test using Locus DR/DQ, Terasaki Second DR W-60 Tray and using following antibodies; DR 1, DR 2, DRW 15, DR 4, DR 5, DR 7, DR 9, DRW 10, DRW 8, DRW 12, DRW 13, DRW 6, DRW 52, DRW 53, DQW 1, DQW 6, DQW 2, DQW 3, DQW 7 and DQW 4. No significant differences between HLA-DR/DQ of nonresponders and responders were noted. PMID:2601078

  10. Dr. Hugh L. Dryden - portrait

    NASA Technical Reports Server (NTRS)

    1959-01-01

    Dr. Hugh Latimer Dryden, had many titles after his name in his lifetime. In 1949 he became the director of the National Advisory Committee for Aeronautics (NACA). Dr. Dryden received many accolades and awards both during his life and after his death, but the greatest and most appropriate honor came on March 26, 1976, when NASA renamed the NASA Flight Research Center as the NASA Hugh L. Dryden Flight Research Center. At the dedication ceremony NASA Administrator James C. Fletcher stated: 'in 1924, when the fastest racing planes did well to fly at 280 m.p.h., Dryden was already probing the transonic range of . . . flight. Later in the 1920s, he sought to develop methods of accurately measuring . . . turbulence in wind tunnels. In 1938 he was the first American to deliver the Wright Brothers lecture. His 'Turbulence and the Boundary Layer' became a classic summary on the subject. It is most fitting that this Flight Research Center, with its unique and highly specialized capability for solving aerospace problems, should memorialize the genius of Hugh Dryden.' Dr. Dryden was initially an aerodynamicist with the National Bureau of Standards. He did important early work in high-speed aerodynamics. In 1947 he became the director of aeronautical research for the NACA (a predecessor of the National Aeronautics and Space Administration). Two years later, he became NACA's director, a position he held until 1958 when he became deputy administrator of NASA.

  11. White Dwarfs in SDSS DR9 and DR10

    NASA Astrophysics Data System (ADS)

    Gentile Fusillo, Nicola Pietro; Gänsicke, Boris; Koester, Detlev

    2015-06-01

    Currently the largest catalogue of spectroscopically identified WDs is based on the 7th Data Release (DR) of the Sloan Digital Sky Survey and contains over 20000 WDs (Kleinman et al. 2013). However, only a fraction of all WDs in the photometric footprint of SDSS have been spectroscopically followed up. Using DR7 spectroscopy as a training sample, we developed a method to select high confidence photometric WD candidates. The novelty of our selection is that it allows us to assign to any object with multi-colour and proper motion data a well-defined "probability of being a white dwarf" (or a contaminant). Exploiting this selection method we compiled a catalogue (Gentile Fusillo et al. in prep) which currently covers the entire photometric footprint of SDSS, 14555sq deg, with a limiting magnitude of g ≤ 19. The catalogue contains over 20000 high-confidence WDs and WD candidates 11500 of which have not yet been followed up with Sloan spectroscopy. Even though, so far, our catalogue relies only SDSS we plan to extend the sky coverage as additional deep multi-colour large area surveys become available. DR10 includes over 1.4 million spectra taken with the new BOSS spectrograph, which improves over the original SDSS spectograph in both resolution and wavelength coverage, but has so far not been systematically mined for WD science. As part of this project, we also inspected over 8000 BOSS spectra of bright (g ≤ 19) colour selected sources and classified 1765 new WDs. We used this independent, spectroscopically confirmed sample to further validate our selection method. Finally we discuss possible application of our catalogue , focusing on the selection and follow up of 9 new DZs which show strong pollution from elements other than Ca and IR excess emission emission consistent with the presence of debris discs.

  12. [Cutaneous myiasis by Cochliomyia hominivorax (Coquerel) (Diptera Calliphoridae) in Hospital Universidad del Norte, Soledad, Atlántico].

    PubMed

    de la Ossa, Napoleón; Castro, Luis Eduardo; Visbal, Lila; Santos, Ana María; Díaz, Esther; Romero-Vivas, Claudia M E

    2009-03-01

    Human myiasis is the parasitism of human tissues by fly larvae. Diagnoses are based on clinical pattern of tissue damage and presence of insect stages. Herein, a case myiasis is described in a seven-year-old female child. She presented with fever associated with abscessed scalp lesions containing exposed larvae. Severe pediculosis was also observed. The patient was hospitalized and treated with clindamycin, gentamicin (for bacterial secondary infections) and ivermectin (treatment for lice) after which the patient showed clinical improvement and was discharged four days later. Since human myiasis can be caused by a number of different species, larvae were collected from the patient and identified as those of Cochliomyia hominivorax (Diptera: Calliphoridae). Because other cases of coinfestation of flies and lice are on record, health workers are to be alerted about the possible pediculosis-myasis risk. PMID:19753834

  13. [DR. ARIEH LEIB SHIMONI-MEKLER - EYE, EAR, NOSE AND THROAT SPECIALIST].

    PubMed

    Gilbey, Peter; Pikkel, Joseph; Netzer, Aviram; Golz, Avishay

    2016-04-01

    Although the inauguration of the new hospital in Zefat built by Baron Rothschild took place in 1910, the building was not used as a hospital until World War I when it was confiscated by the Turks for patients affected with typhus, and later it was converted into a military hospital. The second inauguration of the renewed hospital was in June 1919, and the medical activity was assigned to the American Zionist Medical Unit for Palestine' (AZMU), later - 'Hadassah Medical Organization'. Among the first doctors that were sent to Zefat by AZMU was Dr. Arieh Leib Shimoni-Mekler - Eye, Ear, Nose and Throat specialist. Dr. Shimoni-Mekler worked in the hospital during the years 1921-2. PMID:27323542

  14. Dr. Harry Whelan With the Light Emitting Diode Probe

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The red light from the Light Emitting Diode (LED) probe shines through the fingers of Dr. Harry Whelan, a pediatric neurologist at the Children's Hospital of Wisconsin in Milwaukee. Dr. Whelan uses the long waves of light from the LED surgical probe to activate special drugs that kill brain tumors. Laser light previously has been used for this type of surgery, but the LED light illuminates through all nearby tissues, reaching parts of tumors that shorter wavelengths of laser light carnot. The new probe is safer because the longer wavelengths of light are cooler than the shorter wavelengths of laser light, making the LED less likely to injure normal brain tissue near the tumor. Also, it can be used for hours at a time while still remaining cool to the touch. The probe was developed for photodynamic cancer therapy under a NASA Small Business Innovative Research Program grant. The program is part of NASA's Technology Transfer Department at the Marshall Space Flight Center.

  15. 100-DR-1 radiological surveys

    SciTech Connect

    Naiknimbalkar, N.M.

    1994-01-28

    This report summarizes and documents the results of the radiological surveys conducted over the surface of the 100-DR-1 Operable Unit, Hanford Site, Richland, Washington. In addition, this report explains the survey methodology using the Ultrasonic Ranging and Data System (USRADS). The 100-DR-1 radiological survey field task consisted of two activities: characterization of the operable unit-specific background conditions and the radiological survey of the operable unit surface area. The survey methodology was based on utilization of USRADS for automated recording of the gross gamma radiation levels at or near 6 in. and at 3 ft from the surface soil. The purpose of the survey is to identify the location of unidentified subsurface radioactive material areas and any surface contamination associated with these areas. The radiological surveys were conducted using both a digital count rate meter with a NaI detector reporting in counts per minute (CPM) and a dose rate meter reporting micro-Roentgen per hour (uR) connected to a CHEMRAD Tennessee Corp. Series 2000 USRADS. The count rate meter was set for gross counting, i.e., Window ``out``. The window setting allows detection of low, intermediate, and high energy photons. The USRADS equipment is used to record the detector readings verses the location of the readings, generate a map of the survey area, and save the data on computer storage media.

  16. Interview with Dr. Charley Zeanah

    PubMed Central

    2013-01-01

    Dr. Charles Zeanah is the Mary K. Sellars-Polchow Chair in Psychiatry, Professor of Clinical Pediatrics and Vice Chair for Child and Adolescent Psychiatry in the Department of Psychiatry and Behavioral Sciences at Tulane University School of Medicine in New Orleans. He is also Executive Director of the Institute for Infant and Early Childhood Mental Health at Tulane. He is the recipient of multiple awards including the Irving Phillips Award for Prevention, (AACAP), the Presidential Citation for Distinguished Research and Leadership in Infant Mental Health (American Orthopsychiatric Association), the Sarah Haley Memorial Award for Clinical Excellence (International Society for Traumatic Stress Studies), the Blanche F. Ittelson Award for Research in Child Psychiatry (APA), and the Serge Lebovici Award for International Contributions in Infant Mental Health (World Association for Infant Mental Health). Dr. Zeanah is a Distinguished Fellow of AACAP, a Distinguished Fellow of the APA and a Board Member of Zero to Three. He is the Editor of Handbook of Infant Mental Health (3rd edition) considered as the state of the art textbook and standard reference in the field of Infant Mental Health. PMID:23667354

  17. Dr. von Braun, Dr. Mueller, and Dr. Rees at the Firing Room During the SA-6 Launch

    NASA Technical Reports Server (NTRS)

    1964-01-01

    This photograph depicts an intense moment during the SA-6 launch at the Firing Room. Dr. von Braun, Director of the Marshall Space Flight Center (MSFC) is at center; to his left is Dr. George Mueller, Associate Director for Marned Space Flight; and far right is Dr. Eberhard Rees, Director for Research and Development, MSFC. The SA-6, the sixth flight of the Saturn 1 vehicle, launched a S-IV stage (a second stage) and an Apollo boilerplate spacecraft.

  18. Experience of Preimplantation Genetic Diagnosis for Hemophilia at the University Hospital Virgen Del Rocío in Spain: Technical and Clinical Overview

    PubMed Central

    Fernández, Raquel M.; Peciña, Ana; Sánchez, Beatriz; Lozano-Arana, Maria Dolores; García-Lozano, Juan Carlos; Pérez-Garrido, Rosario; Núñez, Ramiro; Borrego, Salud; Antiñolo, Guillermo

    2015-01-01

    Hemophilia A and B are the most common hereditary hemorrhagic disorders, with an X-linked mode of inheritance. Reproductive options for the families affected with hemophilia, aiming at the prevention of the birth of children with severe coagulation disorders, include preimplantation genetic diagnosis (PGD). Here we present the results of our PGD Program applied to hemophilia, at the Department of Genetics, Reproduction and Fetal Medicine of the University Hospital Virgen del Rocío in Seville. A total of 34 couples have been included in our program since 2005 (30 for hemophilia A and 4 for hemophilia B). Overall, 60 cycles were performed, providing a total of 508 embryos. The overall percentage of transfers per cycle was 81.7% and the live birth rate per cycle ranged from 10.3 to 24.1% depending on the methodological approach applied. Although PGD for hemophilia can be focused on gender selection of female embryos, our results demonstrate that methodological approaches that allow the diagnosis of the hemophilia status of every embryo have notorious advantages. Our PGD Program resulted in the birth of 12 healthy babies for 10 out of the 34 couples (29.4%), constituting a relevant achievement for the Spanish Public Health System within the field of haematological disorders. PMID:26258137

  19. Dr. Francis Collins Is New NIH Director

    MedlinePlus

    ... that, with Dr. Collins at the helm, the Human Genome Project met its milestones ahead of schedule and under budget. The project concluded successfully in April 2003 with the complete map of the human genome, the instruction book for peoples' DNA. Dr. Collins ...

  20. Dr. Wernher Von Braun greeting dignitaries.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun, left, greets vice president Spiro T. Agnew in the Launch Control Center for the Apollo 14 mission. Between Dr. Von Braun and Mr. Agnew are their Royal Highnesses, The Prince and Princess of Spain. The royal visitors greeted the launch control team in th enter after the launch of Apollo 14.

  1. Dr. Wernher Von Braun at a picnic.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun, director of the Marshall Space Flight Center, stakes claim to a table for the picnic celebrating man's first lunar landing. With Dr. Von Braun are his wife, Maria (seated, right), and son, Peter (back to camera). His daughter, Margrit, was also present, but is hidden from view by friends in this view.

  2. [Portrait of Dr Milenko Petrović (1884-1950)].

    PubMed

    Kljaić, Leposava; Borota, Radoslav

    2008-01-01

    Dr Milenko Petrović was one of the very distinguished physicians in the history of Sombor city, who significantly contributed to the development of health care in Voivodina. His father Dimitrije was a professor in the High Teacher-training School in Sombor, recognized writer and politician of his epoch. He was born in Sombor in 1884, where he was educated and finished grammar school. For medical studies he moved to Budapest as a boarder of the famous Tekelianum, and graduated in 1908. He started specialisation in surgery, but being a great patriot he voluntarily recruited in the Serbian army to fight in Balkan liberation wars against Turkey. For his excellent work as a war surgeon he obtained many recognitions. After completing specialization in surgery in Debrecin, he returned to his native city Sombor, where he intended to practice as a physician, but because af the outbreak of the first world he was mobilized and sent to the front in Galicia. After the war he again returned to Sombor where he was immediatelly nominated for the main county physician and then begins his fruitful many year's work on the establishment and promotion of the health care in Sombor and broader territory. As the main county phsician he initiated the foundation and construction of the hospital in Sombor, because of high mortality rate among children, and spreading of contagious diseases like tuberculosis and trachoma. The construction of the hospital was completed in 1925 and Dr. Petrović was appointed its first director and this duty he performed for many years till the World War 2 in 1941. Under his management the hospital in Sombor became one of the best quality hospitals in the country and gave a big contribution to the promotion of health of the inhabitants of Voivodina. In spite of his extensive duties in the hospital. Dr. Milenko Petrović was very much engaged in social work, as the president of library "Laza Kosti ć". in the Soko association, Fire brigade, Rotary club, and he

  3. From the Field: Speech Therapy Outcome Measures--Interview with Dr. Pam Enderby

    ERIC Educational Resources Information Center

    Montgomery, Judy K.

    2015-01-01

    This article is an interview with Dr. Pam Enderby--a speech language therapist and professor at the Institute of General Practice and Primary Care at the University of Sheffield, Community Sciences Centre, Northern General Hospital, in the United Kingdom--conducted by Judy Montgomery, Editor in Chief, of "Communication Disorders…

  4. [Interview with Dr. Ricardo Bressani].

    PubMed

    1994-01-01

    In an interview Dr. Ricardo Bressani, a chemical engineer by profession and a consultant of the Institute of Nutrition of Central America and Panama (INCAP), talks about the search for a product later given the name of Incaparina, which was eventually developed for food supplementation programs by INCAP. Experiments were made with soybeans, cottonseed, and various cereals to arrive at the optimal mixture of 62% cereal and 38% protein for this product. In addition, vitamins and lysine were added. The major demand for this biscuit occurred between 1976 and 1978. Since that time sales have ebbed partly owing to the soaring commodity prices. Incaparina is sold in Guatemala and El Salvador and there are tests going on in Mexico, Colombia, and Cuba to produce it locally. This product is also proof of the benefit of developing leguminous cereal systems. The optimal combination is 70% cereals and 30% legumes, each providing 50% protein. The potential of mixing various other cereals and fruits are also being studied. A large number (up to 60 annually) of nutritional research papers are published on the national level and in Latin America in prestigious scientific journals whose monitoring calls for coordination between different authors. PMID:12295846

  5. Dr. Sadik decries early parenthood.

    PubMed

    1991-01-01

    At the Tenth Anniversary Conference of the Center for Population Options, which was held in Washington on September 24, 1990, Dr. Nafis Sadik, Executive Director of the United Nations Population Fund (UNFPA), spoke concerning the problems created by early parenthood. Childbirth is the greatest health risk young women, after reaching puberty, face in developing countries; their children are less likely to survive than those born to those over 20. Early childbearing means larger families; this, when combined with shorter time spans between generations, leads to rapid population growth and endangers sustainable development in societies with limited natural resources. As a social and economic issue, adolescent fertility limits educational achievement, status, and full participation in the community for women and girls. In many societies, women are second class citizens; they are more likely to die in infancy than boys, they are less likely to attend school, and they leave school earlier. They derive their status from motherhood and spend practically all of their fertile years pregnant and caring for children. They have no other option because their futures are determined by others. PMID:12346165

  6. Dr Valter Rukavina - amateur painter.

    PubMed

    Glavocic, Daina

    2008-01-01

    In this essay Dr Valter Rukavina (Rijeka 1896-1972), excellent specialist in infectious diseases and professor of the Rijeka University School of Medicine, is presented as successful amateur painter. He had been refining his talent through relentless practice since the school days, complementing it with skills and advice from established painters he associated with. He favoured figurative, realistic and somewhat romantic expression for his themes such as coastal landscapes, marinas, Quarnero sceneries, still life in tempera or oil, and drawings in ink or sepia. Despite partial colour blindness, he successfully used colour. He featured in a number of group exhibitions such as that of amateur painters of Rijeka in 1950, of painters physicians of Yugoslavia (Zagreb, 1956), in the Second International Exhibition of Contemporary Art (Florence, 1964), exhibition of the Rijeka branch of the Croatian Association of Visual Artists (Belgrade, 1966), and the 1969 exhibition in Opatija. His native city hosted two one-man exhibitions, the first retrospective in 1971, while he was still alive, and the second posthumous in 2007, with a good selection of his life's work. PMID:20136338

  7. Letter to Dr. Felix Bronner

    NASA Technical Reports Server (NTRS)

    Greenleaf, John E.; Dalton, Bonnie (Technical Monitor)

    2002-01-01

    Dear Dr. Bronner: I have been reading in The Physiologist the letters from senior physiologists for many years with great interest. It is impressive that many of the respondents are still pursuing scientific endeavours in their 70's and some even in their 80's. The interesting task is to ponder the relative causative proportions of heredity and environment responsible. One wonders whether knowing something about physiology engenders longer and more productive lives? I suspect so because of the accompanying self-discipline. But another factor would seem to be the pervasive joy of working in this profession. I have been fortunate to be able to acquire the joy of physiology during my graduate studies at Illinois, and to have been able to carry it over here at NASA, Ames Research Center for the past 40 years. A truly academic style research environment at a federal research center is rare. The trick to a joyous research career is to overcome those ever-present slings and arrows of outrageous fortune with dignity whenever possible. To that end I have found solace and guidance in reading the history of warfare and its leaders, especially Sun Tsu's The Art of War and Clauswitz's On War. I became eligible for retirement in 1993, but to insure domestic tranquility and also the joy of pursuing my research hobby have continued working in the laboratory on human research. It is troubling to see that funding for individual scientists conducting human research is declining rapidly, along with their new ideas; perhaps the old ones are more comfortable. Hopefully I can provide a similar response when I'm 80! Thanks for your interest. Sincerely, John Greenleaf

  8. Dr. Wernher von Braun in his Office

    NASA Technical Reports Server (NTRS)

    1960-01-01

    Dr. Wernher von Braun is in his office, with an artist's concept of a lunar lander in background and models of Mercury-Redstone, Juno, and Saturn I. Dr. Wernher von Braun, the first MSFC Director, led a team of German rocket scientists, called the Rocket Team, to the United States, first to Fort Bliss/White Sands, later being transferred to the Army Ballistic Missile Agency at Redstone Arsenal in Huntsville, Alabama. They were further transferred to the newly established NASA/Marshall Space Flight Center (MSFC) in Huntsville, Alabama in 1960, and Dr. von Braun became the first Center Director.

  9. Dr. Robert H. Goddard and His Rockets

    NASA Technical Reports Server (NTRS)

    1926-01-01

    Dr. Robert H. Goddard and liquid oxygen-gasoline rocket in the frame from which it was fired on March 16, 1926, at Auburn, Mass. It flew for only 2.5 seconds, climbed 41 feet, and landed 184 feet away in a cabbage patch. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets, which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

  10. [Dr. John Baptiste Edouard Gélineau].

    PubMed

    Janković, S; Susić, V; Sokić, D; Lević, Z

    1996-01-01

    became the "Intern" of the Navy Hospital and next year a "Surgeon of the Third Class". As a Navy surgeon he visited French colonies in the Indian ocean: first the Reunion island and then Mayotte island of the Commores Archipelago. Of this period he wrote "Voyage a i'lle de la Réunion", memoirs published much later, in 1905, in which he described colonial life and abolition of slavery. The story of Elise, a beauteous Creole woman, a concubine of a young naval Commander, who delivered a child that soon died, inexorably points to the autobiographic character of his work. He defended a doctoral thesis "Aperçu Medical de I'lle de Mayotte" at Montpellier University School of Medicine in 1858, using the data collected during his year-and-a-half stay on a Mayotte island; at that time he was a "Navy Surgeon of the Second Class". For his dedication in fighting against epidemics that broke out during the French-German war in 1870 he was nominated for the Legion of Honor, but received it only later. In 1871 Gélineau introduced "Doctor Gélineau's tablets" for the treatment of epilepsy (contained bromide and arsenic). He was a member of the Société de Médicine, Société d' Hypnologie, La-Société Française d' Hygiène, and a few others. After retirement at the age of 72, Gélineau switched to wine production, continuing the family tradition; for the quality of his Bordeaux wines he was awarded gold medals at the Anvers and Paris Exhibitions. Dr. Gélineau died on March 2, 1906, at Argeles Gazost in Pyrnees honored by the titles of Chevalier de la Légion d' Honneur, Officier d'Academie and Commander of Nichan of the Ottoman Empire. PMID:9132972

  11. Dr. von Braun With German Rocket Experimenters

    NASA Technical Reports Server (NTRS)

    1930-01-01

    Dr. von Braun was among a famous group of rocket experimenters in Germany in the 1930s. This photograph is believed to be made on the occasion of Herman Oberth's Kegelduese liquid rocket engine being certified as to performance during firing. From left to right are R. Nebel, Dr. Ritter, Mr. Baermueller, Kurt Heinish, Herman Oberth, Klaus Riedel, Wernher von Braun, and an unidentified person.

  12. Childhood Picture of Dr. von Braun

    NASA Technical Reports Server (NTRS)

    1912-01-01

    This is a childhood picture of Dr. von Braun (center) with his brothers. Dr. Wernher von Braun was born in Wirsitz, Germany, March 23, 1912. His childhood dreams of marned space flight were fulfilled when giant Saturn rockets, developed under his direction at NASA's Marshall Space Flight Center, boosted the manned Apollo spacecraft to the Moon. His life was dedicated to expanding man's knowledge through the exploration of space.

  13. Dr. von Braun at the Farewell Ceremony

    NASA Technical Reports Server (NTRS)

    1970-01-01

    Dr. von Braun was honored with a series of farewell events and ceremonies prior to his reassignment to NASA Headquarters in Washington, D.C. Alabama Governor Brewer greets Dr. von Braun following his speech at the front of the Madison County Courthouse in Huntsville, Alabama on February 24, 1970. Behind are Madison County Commissioner James Record, Huntsville Mayor Joe Davis, and U.S. Senator Sparkman.

  14. Frequency of cancer in children residing in Mexico City and treated in the hospitals of the Instituto Mexicano del Seguro Social (1996–2001)

    PubMed Central

    Juárez-Ocaña, Servando; González-Miranda, Guadalupe; Mejía-Aranguré, Juan Manuel; Rendón-Macías, Mario Enrique; Martínez-García, María del Carmen; Fajardo-Gutiérrez, Arturo

    2004-01-01

    Background The objective of this article is to present the frequency of cancer in Mexican children who were treated in the hospitals of the Instituto Mexicano del Seguro Social in Mexico City (IMSS-MC) in the period 1996–2001. Methods The Registry of Cancer in Children, started in 1996 in the IMSS-MC, is an on-going, prospective register. The data from 1996 through 2001 were analyzed and the different types of cancer were grouped according to the International Classification for Cancer in Children (ICCC). From this analysis, the general and specific frequencies by age and by sex were obtained for the different groups of neoplasms. Also, the frequency of the stage of the disease that had been diagnosed in cases of children with solid tumors was obtained. Results A total of 1,702 new cases of children with cancer were registered, with the male/female ratio at 1.1/1. Leukemias had the highest frequency with 784 cases (46.1%) and, of these, acute lymphoblastic leukemias were the most prevalent with 614 cases (78.3%). Thereafter, in descending order of frequency, were tumors of the central nervous system (CNST) with 197 cases (11.6%), lymphomas with 194 cases (11.4%), germinal cell tumors with 110 cases (6.5%), and bone tumors with 97 cases (5.7%). The highest frequency of cancer was found in the group of one to four year-olds that had 627 cases (36.8%). In all the age groups, leukemias were the most frequent. In the present work, the frequency of Hodgkin's disease (~4%) was found to be lower than that (~10%) in previous studies and the frequency of tumors of the sympathetic nervous system was low (2.3%). Of those cases of solid tumors for which the stage of the disease had been determined, 66.9% were diagnosed as being Stage III or IV. Conclusions The principal cancers in the children treated in the IMSS-MC were leukemias, CNST, and lymphomas, consistent with those reported by developed countries. A 2.5-fold reduction in the frequency of Hodgkin's disease was found

  15. [Dr. Moritz Wallach--a century of medicine and tradition in Shaare Zedek].

    PubMed

    Navot, Orit

    2003-06-01

    Dr. Wallach, who founded the Shaare Zedek Hospital and managed the institution for forty-five years, was instrumental in providing modern medical care to Jerusalem residents since his arrival in the city in 1891. He dedicated his life to medicine, to the Jerusalem Jewish community, and to improving the quality of service provided by the existing medical establishment. He was one of the outstanding personalities in a city and community struggling for existence. The Jewish religious character that marks today's Shaare Zedek hospital was determined 100 years ago by Dr. Wallach, who integrated the ancient Jewish moral spirit into a modern medical service tradition. While fulfilling his daily tasks, both as a practicing physician and as the hospital-director, Dr. Wallach became a role model to those who followed him. He mixed freely with the "elite" and his personal relations with local dignitaries, political figures, influential westerners, intellectuals, and important foreign diplomats contributed significantly to the growth, success, and reputation the hospital enjoyed during the last century. On the other hand, he was also personally involved with destitute new immigrants to Eretz Israel and actively engaged in finding jobs, housing, and employment for them. Dr. Wallach became a legend in his own time, both locally and internationally. Due to his professional status and personality, Dr. Wallach became a representative of the Jewish community. He had the ability to speak for the Jews with the Ottoman authorities, and afterwards with the British Mandate authorities. He played a significant role in educating the population in public responsibility, while concurrently leaving his mark on generations of physicians who learned from him the value of precision, loyalty, professional secrecy, and medical responsibility. He was one of the "Giants" of the land (Yishuv) in its critical formative years. PMID:12858837

  16. [[The Lactéol's laboratory of Dr Boucard (Laboratoire du Dr Boucard].

    PubMed

    Raynal, Cécile; Lefebvre, Thierry

    2016-03-01

    Shortly before 1910, Dr Boucard creates his laboratory in Paris. It manufactures and sells a drug based on lactic ferments the " Lactéol du Dr Boucard" (Dr's Boucard Lactéol) that will make the fortune of the physician. The article explains Dr Boucard's life and his relationship with the arts (painting and photography), and tells the story of his laboratory until the 2000s, referring to the pharmacists who succeeded them, as well as the various buildings where were elaborated Lactéol's variants. PMID:27281930

  17. Stroke Hospitalization Down for Many in U.S.

    MedlinePlus

    ... percent among blacks. Dr. Paul Wright, chair of neurology at North Shore University Hospital, in Manhasset, N. ... healthier life," said Towfighi, an assistant professor of neurology at USC's Keck School of Medicine. Healthier lifestyle ...

  18. Geophysical survey of 105-DR Pluto Crib, 116-DR-4, 100-D Area

    SciTech Connect

    Bergstrom, K.A.

    1993-10-01

    The objective of this Geophysical Survey was to verify the location of the 105-DR Pluto Crib, 116-DR-4. A surface monument currently marks its location. The crib is 10 feet by 10 feet and 15 feet deep. Ground-Penetrating Radar was the geophysical method selected to conduct the investigation.

  19. Mother-baby friendly hospital.

    PubMed

    Aragon-choudhury, P

    1996-01-01

    In Manila, the Philippines, the Dr. Jose Fabella Memorial Hospital has been a maternity hospital for 75 years. It averages 90 deliveries a day. Its fees are P200-P500 for a normal delivery and P800-P2000 for a cesarean section. Patients pay what they can and pay the balance when they can. The hospital provides a safe motherhood package that encompasses teaching responsible parenthood, prenatal care, labor, delivery, postpartum care, breast feeding, family planning, and child survival. In 1986, the hospital introduced innovative policies and procedures that promote, protect, and support breast feeding. It has a rooming-in policy that has saved the hospital P6.5 million so far. In the prenatal stage, hospital staff inform pregnant women that colostrum protects the newborn against infections, that suckling stimulates milk production, and that there is no basis to the claim of having insufficient breast milk. Sales representatives of milk substitutes are banned from the hospital. Staff confiscate milk bottles or formula. A lactation management team demonstrates breast feeding procedures. Mothers also receive support on the correct way of breast feeding from hospital staff, volunteers from the Catholic Women's League, consumer groups, and women lawyers. The hospital's policy is no breast milk, no discharge. This encourages mothers to motivate each other to express milk immediately after birth. The hospital has received numerous awards for its breast feeding promotion efforts. UNICEF has designated Fabella Hospital as a model of the Baby-Friendly Hospital Initiative. The hospital serves as the National Lactation Management Education Training Center. People from other developing countries have received training in lactation management here. The First Lady of the Philippines, the First Lady of the US, and the Queen of Spain have all visited the hospital. The hospital has also integrated its existing services into a women's health care center. PMID:12347466

  20. NASA Sponsors Cancer Research at Children's Hospital

    NASA Technical Reports Server (NTRS)

    1998-01-01

    NASA Administrator Dan Goldin (left), during a visit at Children's Hospital of Wisconsin in Milwaukee, Wisconsin, discussed how NASA's special lighting technology may soon treat cancer. Goldin talked with Dr.Harry Whelan (right) and Dr. Kerneth Reichert (center left), both pediatric neurologists with the Hospital and professors at the Medical College of Wisconsin in Milwaukee. Accompanied by Astronaut Mary Ellen Weber, Goldin was shown this innovative treatment, called Photodynamic Therapy, a method used to destroy the tumor without damaging the delicate brain tissue around it. The treatment uses tiny pinhead-size Light Emitting Diodes (LEDs) developed for Space Product Development plant growth experiments.

  1. Dr. Wernher von Braun Laid to Rest

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Dr. Wernher von Braun served as Marshall Space Flight Center's first director from July 1, 1960 until January 27, 1970, when he was appointed NASA Deputy Associate Administrator for Planning. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under Project Paper Clip to continue their rocket development work. In 1950, von Braun and his rocket team were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center. Under von Braun's leadership, Marshall developed the Saturn V launch vehicle which took Apollo astronauts to the moon. Dr. von Braun died in Alexandria, Va., on June 16, 1977, seven years after his NASA appointment. This photo was taken at the site where he was laid to rest.

  2. The Japanese Hospital in Broome, 1910-1926. A harmony of contrasts.

    PubMed

    Stride, P; Louws, A

    2015-01-01

    The Japanese Hospital in Broome remains the only hospital in Australia's history predominantly staffed, controlled and funded by a linguistically, culturally and geographically alien nation. Initially the proposal, challenging prevailing attitudes, was bitterly opposed by the white community, but the hospital became respected thanks to Dr Tadashi Suzuki, the hospital's first doctor, and his successors' clinical skills and compassion. PMID:26181534

  3. Norovirus - hospital

    MedlinePlus

    Gastroenteritis - norovirus; Colitis - norovirus; Hospital acquired infection - norovirus ... fluids ( dehydration ). Anyone can become infected with norovirus. Hospital patients who are very old, very young, or ...

  4. Interview [with Dr. Gerald W. Bracey

    ERIC Educational Resources Information Center

    Journal of Educational Research, 2007

    2007-01-01

    This article presents an interview with Dr. Gerald W. Bracey, author of "Reading Educational Research: How to Avoid Getting Statistically Snookered." During the interview, Bracey explains why he considers the No Child Left Behind Act (NCLB) as a "weapon of mass destruction" and that he sees nothing to suggest that NCLB has improved schools.…

  5. A TRIBUTE TO DR. WILLIAM PENN WATKINSON

    EPA Science Inventory

    Dr. William Penn Watkinson (known to colleagues as "Penn") of EPA¿s health research lab (National Health and Environmental Research Laboratory) of Research Triangle Park, North Carolina, died Wednesday, December 13 after a battle with lung cancer. He was a member of the Pulmonar...

  6. An Interview with Dr. Deborah W. Proctor

    ERIC Educational Resources Information Center

    Landsberger, Joe

    2007-01-01

    In an interview, Dr. Deborah W. Proctor, eCurriculum Director for Academic Innovations/ Minnesota Online and Co-Chair for the MERLOT International Conference, outlines her academic path that led to her current position and interests. As e-Curriculum Director for Academic Innovations in the Office of the Chancellor she works with system…

  7. Dr. von Braun Visits Huntsville Boys Club

    NASA Technical Reports Server (NTRS)

    1961-01-01

    Dr. von Braun, Director of Marshall Space Flight Center (MSFC) and chairman of this year's United Givers Fund (UGF) drive at MSFC, takes time out from the problems of sending a man to the Moon to talk baseball with 11-year-old Randy Smith at the Huntsville Boys Club.

  8. ORAC-DR: Astronomy data reduction pipeline

    NASA Astrophysics Data System (ADS)

    Jenness, Tim; Economou, Frossie; Cavanagh, Brad; Currie, Malcolm J.; Gibb, Andy

    2013-10-01

    ORAC-DR is a generic data reduction pipeline infrastructure; it includes specific data processing recipes for a number of instruments. It is used at the James Clerk Maxwell Telescope, United Kingdom Infrared Telescope, AAT, and LCOGT. This pipeline runs at the JCMT Science Archive hosted by CADC to generate near-publication quality data products; the code has been in use since 1998.

  9. Dr. Akira Tonomura: Master of Experimental Physics

    NASA Astrophysics Data System (ADS)

    Fujikawa, Kazuo

    2014-01-01

    Dr. Akira Tonomura, Hitachi Fellow, passed away on May 2, 2012 at the age of 70. As a classmate at the University of Tokyo and his long-time friend, I would like to describe my personal memory of Tonomura and a brief review of his contributions to fundamental physics.

  10. Dr. Caleb Williams Saleeby: The Complete Eugenicist.

    ERIC Educational Resources Information Center

    Rodwell, Grant

    1997-01-01

    Profiles the work of Dr. Caleb Williams Saleeby, a late 19th-century propagandist for eugenics. Eugenics is a science that deals with the transmission of hereditary racial traits, coupled with a desire to use this for the elimination of social ills. Discusses Saleeby's work with the Eugenics Education Society. (MJP)

  11. Dr. Wernher Von Braun presents a certificate

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (left), director of the Marshall Space Flight Center, presents a humorous certificate to Major General Charles W. Eifler, commanding general of Redstone Arsenal, at the close of a farewell luncheon for the general prior to General Eifler moving to a new European duty station.

  12. Dr. Israel Cuellar (1946-2008)

    ERIC Educational Resources Information Center

    Zamarripa, Manuel X.

    2009-01-01

    On September 7th, 2008, the mental health field lost a trailblazing researcher and clinician as he lost his battle with amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig's disease. Dr. Israel Cuellar made significant contributions to the study of acculturation including its importance in delivering appropriate mental health…

  13. DR and CR: Recent advances in technology.

    PubMed

    Schaefer-Prokop, C M; De Boo, D W; Uffmann, M; Prokop, M

    2009-11-01

    After some initial reluctance, nowadays transition from conventional analogue-to-digital radiographic technique is realized in the vast majority of institutions. The eventual triumph of digital over conventional technique is related to its undoubted advantages with respect to image quality and improved image handling in the context of a picture archiving and communication system. CR represents the older system, which matured over decades and experienced some important recent improvements with respect to dose efficiency and work-flow efficiency that strengthened its position. It represents a very versatile, economically attractive system that is equally suited for integrated systems as well as for cassette-based imaging at the bedside. DR systems offer superb image quality and realistic options for dose reduction based on their high dose efficiency. While for a long time only integrated systems were on the market suited for a large patient throughput, also mobile DR systems became recently available. While for the next years, it is likely that DR and CR systems will coexist, the long term perspective of CR will depend on further innovations with respect to dose efficiency and signal-to-noise characteristics while for DR economical aspects and broader availability of mobile systems will play a role. PMID:19695809

  14. [Establishment and application of DR automatic system based on DICOM3.0 BPE].

    PubMed

    Wang, Longchen; Hu, Shundong; Li, Bin

    2012-01-01

    This paper introduces a new application of PACS in our hospital. Through the integration of PACS, HIS and RIS, digital transformation is made in every step. The functional modules of Body Parts Examined in DICOM is set and good link between PACS and DR is made. So the equipment can retrieval the inspection area automatically and make adjustment on the parameters correspondingly. It makes the workflow optimized and improves the efficiency greatly. PMID:22571147

  15. Leading Healthcare Change Across the Care Continuum: An Interview With Dr Kenneth Rempher.

    PubMed

    Murphy, Lyn Stankiewicz; Joseph, M Lindell

    2016-01-01

    Kenneth Rempher, PhD, MBA, CENP, RN, is the chief nursing officer for the University of Iowa (UI) Hospitals and Clinics. In his 20-year career, he has distinguished himself as a visionary healthcare leader. Colleagues describe Dr Rempher as a strong, transformational leader, guiding the UI enterprise through a time of uncertainty and change. This interview by the CGEAN provides insight to his leadership style, successes, and ideas on the future of care delivery. PMID:27442899

  16. Dr Charles Thomas Jackson's (1805-80) life after death: the 20th century mythology.

    PubMed

    Patterson, Richard

    2007-08-01

    References to Dr Charles Thomas Jackson in 20th century anaesthesia literature and biographical dictionaries and encyclopedias emphasize his maniacal insanity and its relation to his usurpations of the discoveries of others, including the controversy with William TG Morton concerning the honour of the discovery of surgical anaesthesia. In 1873, seven years before his death, he experienced sudden collapse and paralysis requiring hospitalization. Seminal 19th century brain research before his hospitalization correlated the signs and symptoms of his illness with pathology found at his autopsy. PMID:17641787

  17. Dr. Richard J. Whelan: Seeing the Field of Emotional and Behavior Disorders through the Lens of a Pioneer

    ERIC Educational Resources Information Center

    Kaff, Marilyn S.; Teagarden, Jim; Zabel, Robert H.

    2011-01-01

    Dr. Richard J. Whelan is a distinguished professor emeritus at the University of Kansas. His earliest professional experiences were at the Children's Hospital (Southard School) of the Menninger Clinic, where he served as a recreational therapist, teacher, and director of education. During his career at the University of Kansas and the KU Medical…

  18. The Hospital for the Ruptured and Crippled Renamed The Hospital for Special Surgery 1940; The War Years 1941–1945

    PubMed Central

    2008-01-01

    In 1939, the 75th anniversary program marking the founding of the Hospital for the Ruptured and Crippled (R & C), the oldest orthopaedic hospital in the nation, was held at the hospital site in New York City. Dr. Philip D. Wilson, Surgeon-in-Chief since 1935, used this event to mark the return of the hospital to its leadership role in the country. When the Hospital for the Ruptured and Crippled first opened its doors on May 1, 1863, the name of the hospital was not unusual; it described the type of patients treated. In 1940, the Board of Managers with guidance from Dr. Wilson changed the name to the Hospital for Special Surgery (HSS). In 1941, with Britain engaged in a European war, Dr. Wilson felt there was a need for the Americans to support the British. He personally organized the American Hospital in Britain, a privately funded voluntary unit, to help care for the wounded. After the United States actually entered World War II in December 1941, HSS quickly organized support at all levels with a significant number of professional and auxiliary staff, eventually enlisting in the military. Even with such staff turnover, the hospital continued to function under Dr. Wilson’s leadership. After the war ended in 1945, Wilson forged ahead to further restore HSS as a leader in musculoskeletal medicine and surgery. PMID:19048348

  19. [The life of Dr. John William Heron, the second superintendent of Chejungwon].

    PubMed

    Kim, D K; Kim, T S

    2000-12-01

    The purpose of this paper is to overview the life of John W. Heron, M. D. who was the first appointed medical missionary to Korea by the Presbyterian Church USA. Although he was a competent doctor as well as a devoted missionary, he is not well-known yet, because he died early after 5 years' service in Korea. Dr. Heron was born in Derbyshire, England on June 15, 1856. His father, Rev. E. S. Heron, was a Scotch Minister of Congregational Church. His family emigrated to America in 1870 when he was fourteen years old and settled in Knoxville, Tennessee. In 1881, he was admitted to the University of Tennessee Medical School and graduated with highest honors in 1883. After training in New York University Hospital, he refused the offer of professorship from the University of Tennessee to become a medical missionary to Korea. He arrived in Seoul on June 21, 1885 and began to work in Royal Government Hospital, Chejungwon, the predecessor of Severance Hospital. In 1887, he became the superintendent of the Hospital following Dr. Horace N. Allen. He also worked for the Royal family and sometimes traveled to the rural areas to care for the patients. He started Chejungwon Church which later became Namdaemoon Presbyterian Church. In 1887, Dr. Heron worked as a member of the Bible translation committee and in 1889, he was elected as the chairman of the Public Committee of the Presbyterian Churches. In 1890, he established 'The Korean Religious Tract Society (Chosunsyungkyoseohoi) with Underwood and Ohlinger. The society published and replenished Christian books, periodical magazines and booklets. In the Summer of 1890, Dr. Heron did his best to take care of the sick suffering from an epidemic dysentery and himself got infected because of the terrible overwork. He passed away on July 26th, 1890. On his deathbed, he told his soldier and native friends around him as follow: "Jesus loves you. He gave His life for you. Stand by Him!" The martyrdom of Dr. Heron should be remembered in

  20. Hospital Utilization for Injection Drug Use-Related Soft Tissue Infections in Urban versus Rural Counties in California

    PubMed Central

    Etzioni, David A.; Hurley, Brian; Holtom, Paul; Bluthenthal, Ricky N.; Asch, Steven M.

    2006-01-01

    Drug related-soft tissue infections (DR-STIs) are a significant source of hospital utilization in inner-city urban areas where injection drug use is common but the magnitude of hospital utilization for DR-STIs outside of inner-city urban areas is not known. We described the magnitude and characteristics of hospital utilization for DR-STIs in urban versus rural counties in California. All discharges from all nonfederal hospitals in California in 2000 with ICD-9 codes for a soft tissue infection and for drug dependence/abuse were abstracted from the California Office of Statewide Health Planning and Development discharge database. There were 4,152 DR-STI discharges in 2000 from hospitals in 49 of California's 58 counties. Residents of 12 large metropolitan counties accounted for 3,598 discharges (87% of total). The majority of DR-STI discharges were from urban safety net hospitals with county indigent programs and Medicaid as the expected payment source and opiate related discharge diagnoses. Hospital utilization for DR-STIs in California is highest in large urban metropolitan counties, although DR-STI discharges are widespread. Increased access to harm reduction services and drug treatment may reduce government health care expenditures by preventing unnecessary hospital utilization for DR-STIs. PMID:16736367

  1. Dr. von Braun and Dr. Stuhlinger With a Model of the Nuclear-Electric Vehicles

    NASA Technical Reports Server (NTRS)

    2004-01-01

    In this photo, taken at the Walt Disney Studios in California, Dr. Wernher von Braun and Dr. Ernst Stuhlinger are shown discussing the concepts of nuclear-electric spaceships designed to undertake the mission to the planet Mars. As a part of the Disney 'Tomorrowland' series on the exploration of space, the nuclear-electric vehicles were shown in the last three television films, entitled 'Mars and Beyond,' which first aired in December 1957.

  2. Dr. John J. Stephens, Jr., metallurgist extraordinaire.

    SciTech Connect

    Hosking, Floyd Michael

    2010-10-01

    The organizers of the Dr. John J. Stephens, Jr. Memorial Symposium: Deformation and Interfacial Phenomena in Advanced High-Temperature Materials are honoring the memory of Dr. Stephens and his many technical contributions that were accomplished over a relatively brief twenty year career. His research spanned the areas of creep and deformation of metals, dispersion-strengthened alloys and their properties, metal matrix composite materials, processing and properties of refractory metals, joining of ceramic-ceramic and metal-ceramic systems, active braze alloy development, and mechanical modeling of soldered and brazed assemblies. The purpose of this presentation is to highlight his research and engineering accomplishments, particularly during his professional career at Sandia National Laboratories in Albuquerque, NM.

  3. Centennial Presidential Perspective: Dr. Alfred Blalock

    PubMed Central

    Beaty, Claude A.; George, Timothy J.; Conte, John V.

    2014-01-01

    Great men are not a common occurrence. Indeed, they are a rare find. Though respected and lauded in their time, it is only in retrospect that their true contributions can be adequately measured as a surgeon, an educator and a scientist. Such is the case of Dr. Alfred Blalock. Many have considered him the father of modern cardiac surgery. All consider his “blue baby” operation to be one of the landmarks of cardiac surgery and, as the chief of surgery at Johns Hopkins, he trained many who would become the leaders of our discipline. His continual reach for excellence helped him to not only affect, but revolutionize the paradigm of surgical research, an understanding of the physiology of shock and the surgical management of pulmonic stenosis/atresia. Dr. Blalock was the 30th president of the American Association for Thoracic Surgery and his presidential address was given in 1951. PMID:22248679

  4. Dr.L: Distributed Recursive (Graph) Layout

    Energy Science and Technology Software Center (ESTSC)

    2007-11-19

    Dr. L provides two-dimensional visualizations of very large abstract graph structures. it can be used for data mining applications including biology, scientific literature, and social network analysis. Dr. L is a graph layout program that uses a multilevel force-directed algorithm. A graph is input and drawn using a force-directed algorithm based on simulated annealing. The resulting layout is clustered using a single link algorithm. This clustering is used to produce a coarsened graph (fewer nodes)more » which is then re-drawn. this process is repeated until a sufficiently small graph is produced. The smallest graph is drawn and then used as a basis for drawing the original graph by refining the series of coarsened graphs that were produced. The layout engine can be run in serial or in parallel.« less

  5. Dr. Wernher von Braun In His Office

    NASA Technical Reports Server (NTRS)

    1964-01-01

    Dr. Wernher von Braun served as Marshall Space Flight Center's first director from July 1, 1960 until January 27, 1970, when he was appointed NASA Deputy Associate Administrator for Planning. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under Project Paperclip to continue their rocket development work. In 1950, von Braun and his rocket team were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center. Under von Braun's leadership, Marshall developed the Saturn V launch vehicle which took Apollo astronauts to the moon. This photo depicts von Braun in his office at MSFC.

  6. Dr. von Braun Reviewing Spacecraft Plans

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This photograph was taken after Dr. von Braun moved from his post as Director of the Marshall Space Flight Center (MSFC) to Deputy Associate Administrator for Planning at NASA Headquarters. On June 27, 1970, he visited the MSFC again during the center's 10th anniversary to look at a mockup of the spacecraft that would later be known as Skylab. In this photograph, von Braun is talking with George Hardy of the MSFC Astronautics Lab.

  7. Dr. von Braun Reviewing Spacecraft Plans

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This photograph was taken after Dr. von Braun moved from his post as Director of the Marshall Space Flight Center (MSFC) to Deputy Associate Administrator for Planning at NASA Headquarters. On June 27, 1970, he visited the MSFC again during the center's 10th anniversary to look at a mockup of the spacecraft that would later be known as Skylab. In this photograph, von Braun (left) and Fred W. Kelley examine an ST-100 stellar instrument platform in MSFC's Astrionics Lab.

  8. Dr. Wernher Von Braun examines a ruby crystal.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun (right), director of the Marshall Space Flight Center, and Dr. Eberhard Rees (left), deputy director, technical, examine a ruby crystal used in laser experiments in the Marshall Center's Space Sciences Laboratory.

  9. Dr. von Braun Surrenders to U.S. Army

    NASA Technical Reports Server (NTRS)

    1945-01-01

    Dr. Wernher von Braun surrenders to U.S. Army Counterintelligence persornel of the 44th Infantry Division in Ruette, Bavaria on May 2, 1945. Left to right are Charles Stewart, CIC agent; Dr. Herbert Axster; Dieter Huzel; Dr. von Braun (arm in cast); Magnus von Braun (brother); and Hans Lindenberg.

  10. Dr. Wernher Von Braun talkes with George Hardy.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    George Hardy of the Marshall Space Flight center's Astronautics Laboratory, talks with Dr. Wernher Von Braun (right), deputy associate administrator for planning. Dr. Von Braun was inspecting the mockup of the Saturn workshop during a visit to the Marshall Center. The visit coincided with the 10th anniversary celebration of the center of which Dr. Von Braun was director until March 1, 1970.

  11. DR JOHN ADAMCZYK AND DR LONNIE REID EXAMINE SOFTWARE FOR THE NEW START-UP SOFTWARE - ELECTRONICS - A

    NASA Technical Reports Server (NTRS)

    1999-01-01

    DR JOHN ADAMCZYK AND DR LONNIE REID EXAMINE SOFTWARE FOR THE NEW START-UP SOFTWARE - ELECTRONICS - AND COMMUNICATIONS - SEC - INCUBATOR OPENED MAY 1 1999 AS PART OF THE LEWIS INCUBATOR FOR TECHNOLOGY - LIFT

  12. [Life and work of Dr. Bozo Pericić (1865-1947), genius of our medicine].

    PubMed

    Perović, Slavko; Sirovica, Stjepan

    2004-01-01

    The paper describes the life and work of on of our most distinguished physicians--Dr Bozo Pericić. Togheter with another young physician Dr Nikola Lalić the Sibenik hospital became a sort of Meca for medical people. Dr Pericić succeded to clarify an unknown disease--so called "Skrljevo disease", paved the path of to the knowledge about achinococcus etc. He published also number of valuable medical articles and books and avarded a number af aknowledgements. One of the biggest was his nomination for membership of the Supreme Haelth Council in Wienna. He contributed e lot to the medical journals, especially to the "Physician's Journal". As person of wide culture, famous linguist and polyglot Dr Pericić published the "Medical dictionary of Croatian and German Language". He lay foundation of the craniology, quite a new branch of arheology at the time. His accounts of travels, reviews on famous writers, translation of Hamlet, etc--are valuable literary works. PMID:15918326

  13. Dr. von Braun Reviewing Spacecraft Plans

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This photograph was taken after Dr. von Braun moved from his post as Director of the Marshall Space Flight Center (MSFC) to Deputy Associate Administrator for Planning at NASA Headquarters. On June 27, 1970, he visited the MSFC again during the Center's 10th anniversary to look at a mockup of the spacecraft that would later be known as Skylab. Others in the photograph are, from left to right: Karl Heimburg, director of the Astronautics Lab; Hermann K. Weidner, director of Science and Engineering, and George Hardy of the Astronautics Lab.

  14. Dr. von Braun Reviewing Spacecraft Plans

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This photograph was taken after Dr. von Braun moved from his post as Director of the Marshall Space Flight Center (MSFC) to Deputy Associate Administrator for Planning at NASA Headquarters. On June 27, 1970, he visited the MSFC again during the center's 10th anniversary to look at a mockup of the spacecraft that would later be known as Skylab. With von Braun are (left to right): Herman K. Weidner, director of Science and Engineering at MSFC, and James R. Thompson of the center's Astrionics Laboratory.

  15. Dr. von Braun Reviewing Spacecraft Plans

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This photograph was taken after Dr. von Braun moved from his post as Director of the Marshall Space Flight Center (MSFC) to Deputy Associate Administrator for Plarning at NASA Headquarters. On June 27, 1970, he visited the MSFC again to look at a mockup of the spacecraft that would later be known as Skylab. Others in the photograph are, from left to right, James R. Thompson, David Newby, Karl Heimburg, Hermann Weidner, and Jack Stockes. Years later, Thompson would serve as Director of the MSFC.

  16. Dr. von Braun Reviewing Spacecraft Plans

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This photograph was taken after Dr. von Braun moved from his post as Director of the Marshall Space Flight Center (MSFC) to Deputy Associate Administrator for Planning at NASA Headquarters. On June 27, 1970, he visited the MSFC again during the center's 10th anniversary to look at a mockup of the spacecraft that would later be known as Skylab. In this photo, he is examining an experiment in the mockup. With von Braun are (left to right): James R. Thompson, Richard T. Heckman, and Jack Stokes of the Center's Astrionics Laboratory.

  17. A failure management prototype: DR/Rx

    NASA Technical Reports Server (NTRS)

    Hammen, David G.; Baker, Carolyn G.; Kelly, Christine M.; Marsh, Christopher A.

    1991-01-01

    This failure management prototype performs failure diagnosis and recovery management of hierarchical, distributed systems. The prototype, which evolved from a series of previous prototypes following a spiral model for development, focuses on two functions: (1) the diagnostic reasoner (DR) performs integrated failure diagnosis in distributed systems; and (2) the recovery expert (Rx) develops plans to recover from the failure. Issues related to expert system prototype design and the previous history of this prototype are discussed. The architecture of the current prototype is described in terms of the knowledge representation and functionality of its components.

  18. White dwarfs identified in LAMOST DR 2

    NASA Astrophysics Data System (ADS)

    Guo, Jincheng; Zhao, Jingkun; Tziamtzis, Anestis; Liu, Jifeng; Li, Lifang; Zhang, Yong; Hou, Yonghui; Wang, Yuefei

    2015-12-01

    Here we present a catalogue of 1056 spectroscopically identified hydrogen-dominated white dwarfs (DAWDs), 34 helium-dominated white dwarfs (DBWDs) and 276 white dwarf main sequence (WDMS) binaries from the Large sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) survey data release 2 (DR2). 383 DAWDs, 4 DBWDs and 138 WDMSs are new identifications after cross-match with literature. There are ˜4100 k spectra in total from DR 2. The low ratio of white dwarfs found in LAMOST is attributed to biased selection of LAMOST input catalogue and much brighter targets relative to stars observed in Sloan Digital Sky Survey. In this paper, a new DAWD selection method is adopted as a new attempt and supplement to the traditional methods. The effective temperature, surface gravity, mass, cooling age and distance of high signal-to-noise DAWDs are estimated. The peak of the mass distribution is found to be ˜0.6 M⊙, which is consistent with previous work. The parameters of WDMS binaries are also provided in this paper. As the foundation of our future work, which is to identify more WDs with debris disc, WDs found in LAMOST showed a lot of potential. Interesting infrared-excess WDs will be reported in our forthcoming paper.

  19. High-risk genotypes HLA-DR3-DQ2/DR3-DQ2 and DR3-DQ2/DR4-DQ8 in co-occurrence of type 1 diabetes and celiac disease.

    PubMed

    Smigoc Schweiger, Darja; Mendez, Andrijana; Kunilo Jamnik, Sabina; Bratanic, Nina; Bratina, Natasa; Battelino, Tadej; Brecelj, Jernej; Vidan-Jeras, Blanka

    2016-06-01

    Shared susceptibility alleles in the HLA region contribute to the co-existence of type 1 diabetes (T1D) and celiac disease (CD). The aim of our study was to identify HLA genotype variations that influence co-occurrence of T1D and CD (T1D + CD) and the order of their onset. Totally 244 patients, 67 with T1D, 68 with CD and 69 with T1D + CD, (split into "T1D first" and "CD first"), were analyzed. Control group consisted of 130 healthy unrelated individuals. Two-tailed Fisher's exact test was used for statistical analysis. The genetic background of Slovenian CD patients resembled more northern than southern European populations with DR3-DQ2/DR3-DQ2 (odds ratio [OR] = 19.68) conferring the highest risk. The T1D + CD was associated with DR3-DQ2/DR3-DQ2 (OR = 45.53) and even more with DR3-DQ2/DR4-DQ8 (OR = 93.76). DR3-DQ2/DR7-DQ2 played a neutral role in susceptibility for T1D + CD. The order of the onset of T1D or CD in patients with co-occurring diseases was not influenced by HLA risk genotype profile. DR3-DQ2/DR3-DQ2 was associated with an increased risk for developing CD in patients with T1D, whereas patients with CD carrying DR3-DQ2/DR4-DQ8 were at higher risk for developing T1D. In addition to other genetic factors including HLA class I alleles present on DR3-DQ2 extended haplotype, the second extended haplotype may moderate the risk for T1D + CD conferred by DR3-DQ2. Our results suggested that individuals carrying high-risk genotypes DR3-DQ2/DR3-DQ2 or DR3-DQ2/DR4-DQ8 would more likely develop both T1D and CD than either disease alone. PMID:27138053

  20. Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    ScienceCinema

    Chu, Steven (U.S. Energy Secretary)

    2012-06-28

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

  1. Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    SciTech Connect

    Chu, Steven

    2012-05-07

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

  2. The life-work of Prof. MUDr. Zdenek Lojda, Dr.Sc., Dr. Med. et Iur. h.c.

    PubMed

    Hach, P

    2008-01-01

    Professor Zdenek Lojda, MD., Dr.Sc., Dr. Med.h.c., Dr. Jur. h.c., vice-rector emeritus of the Charles University and director emeritus of the Institute of Histology and Embryology of the 1st Medical Faculty of the Charles University in Prague died on the 24th April 2004. Born in Trebíc (in a local maternal hospital on the 7th December 1927) he grew up in Moravské Budejovice where he graduated from a primary and secondary school (he passed out each class as well as the leaving exam at the local gymnasium in 1946 cum laude). He was growing up in an inspiring atmosphere of a family of a professor at gymnasium that helped him to form his fundamental moral attitude and to gain high knowledge of an almost Renaissance comprehension. He was a gifted linguist (he spoke fluently several languages including Latin) and musician (he did community singing among others) and he was interested in natural sciences. In 1946 he enrolled for the medical faculty and coincidentally he was grouped among students that completed histology and embryology at the Institute of Embryology headed by professor Zdenek Frankenberger, MD., who had recognised his interest in this field of study. The young student gave himself and his free time to the work of an unqualified lab-worker and only later he became assistant conducting practical tutorials. He took his degree cum laude in 1952 and he received certificate of competence because of his excellent results. He showed his preoccupation with histology (strongly influenced by the personality of professor Frankenberger) after the graduation when he entered the job of the assistant professor at the Institute of Embryology and he stayed there until 1961. When he was about to decide which problems he should target, professor Frankenberger drew his attention to a very interesting part of histology that was just in advance and that was the use of diazonic salts for formation of colour reaction product demonstrating enzyme activity in tissues. In 1962

  3. Dr. Cheryl Nickerson studies Salmonella Typhimurium

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Dr. Cheryl Nickerson of Tulane University is studying the effects of simulated low-g on a well-known pathogen, Salmonella typhimurium, a bacterium that causes two to four million cases of gastrointestinal illness in the United States each year. While most healthy people recover readily, S. typhimurium can kill people with weakened immune systems. Thus, a simple case of food poisoning could disrupt a space mission. Using the NASA rotating-wall bioreactor, Nickerson cultured S. typhimurium in modeled microgravity. Mice infected with the bacterium died an average of three days faster than the control mice, indicating that S. typhimurium's virulence was enhanced by the bioreactor. Earlier research showed that 3 percent of the genes were altered by exposure to the bioreactor. Nickerson's work earned her a 2001 Presidential Early Career Award for Scientists and Engineers.

  4. Dr. Goddard and a 1918 version of 'Bazooka'

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Dr. Robert H. Goddard loading a 1918 version of the Bazooka of World War II. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets, which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

  5. Entrevue avec le Dr Charley Zeanah

    PubMed Central

    2013-01-01

    Le Dr Charles Zeanah est titulaire de la chaire de psychiatrie Mary K. Sellars-Polchow, professeur de pédiatrie clinique et vice-président de la pédopsychiatrie au département de psychiatrie et des sciences du comportement de la faculté de médecine de l’Université Tulane, à la Nouvelle-Orléans. Il est également directeur général de l’institut de la santé mentale des nourrissons et des jeunes enfants de Tulane. Il est récipiendaire de nombreux prix, notamment le prix de prévention Irving Phillips (AACAP), la mention élogieuse présidentielle pour sa recherche et son leadership exceptionnels en santé mentale des nourrissons (American Orthopsychiatric Association), le prix d’excellence clinique Sarah Haley Memorial (International Society for Traumatic Stress Studies), le prix de recherche en pédopsychiatrie Blanche F. Ittelson (APA), et le prix Serge Lebovici Award soulignant les contributions internationales à la santé mentale des nourrissons (World Association for Infant Mental Health). Le Dr Zeanah est fellow distingué de l’AACAP, fellow distingué de l’APA et membre du conseil d’administration de Zero to Three. Il est l’éditeur scientifique de Handbook of Infant Mental Health (3e édition) qui est considéré comme étant le manuel de pointe et la référence de base du domaine de la santé mentale des nourrissons.

  6. [Historical exploration of Acapulco hospitals, Guerrero, Mexico].

    PubMed

    Fajardo-Ortiz, Guillermo; Salcedo-Alvarez, Rey Arturo

    2006-01-01

    This study attempts to recount the history of the main hospitals of the port of Acapulco from colonial times until the end of the 20th century. The Augustine friars began hospital care at the end of the first part of the 16th century. Later, Bernardino Alvarez (1514?-1584), with the support of the Spanish crown, founded the first formal hospital in Acapulco called Hospital de Nuestra Señora de la Consolación (Our Lady of Consolation Hospital). During the 16th and 17th centuries, the sick were attended by friars, and by the end of the 19th century there were physicians and surgeons. From the end of the Independence War until the end of the 19th century, the port did not have any true hospital. The first degreed physicians and surgeons arrived and resided in Acapulco in 1920. In 1938, the Hospital Civil Morelos (Morelos Civil Hospital) began providing services. It was replaced by the Hospital General de Acapulco (General Hospital of Acapulco). At the fourth decade of the past century the Cruz Roja (Red Cross) was created. In 1957 the hospital services of the Instituto Mexicano del Seguro Social (IMSS, Mexican Institute of Social Security), which was founded in 1963, was inaugurated with the Unidad Medico/Social (Medical and Social Unit) of the IMSS in Acapulco. This began the journey of modernity in Acapulco. In 1992, Hospital Regional Vicente Guerrero (Regional Hospital Vicente Guerrero) of the IMSS, initiated its services. In 1960, medical services for civil workers and their families were housed in the Hospital Civil Morelos (Morelos Civil Hospital). Shortly afterwards, the Instituto de Seguridad y Servicios Sociales para los Trabajadores del Estado (ISSSTE, Security and Social Services Institute for State Employees) had their own hospital. During the 20th century, Acapulco has added other hospital services to care for members of the navy and armed forces, as well as for those persons with financial resources for private care. PMID:17244509

  7. A Crusade Against Scorpion Sting: Life and Works of Dr. Himmatrao Bawaskar

    PubMed Central

    Kale, Ajinkya A.

    2012-01-01

    In the times of rapid advancement of science and technology, advance medical equipment and hi tech hospitals represent the face of medical science. The aspirations and ambitions of medical professionals are also shifting, with growing concerns of deterioration of doctor patient relationship as well as disconnect between services and the community needs. The life of Dr Himmatrao Bawaskar defies several conventions of today's medical practice. His outstanding dedication towards patients and commitment to provide high quality care in resource poor setting makes him an ideal role model for younger generation of physicians in India. PMID:24479002

  8. [Red Cross hospital in Krapina, during the First world war from 1914 to 1918].

    PubMed

    Fures, Rajko; Habek, Dubravko; Kozina, Drago

    2016-08-01

    Red Cross Hospital in Krapina, during the First World War, was active from 1914 to 1918. Hospital led by Dr. Mirko Crkvenac, oriented humanist. The hospital is operated thanks to the help of municipalities and citizens. The hospital staff concern is for civilian and military victims of the First World War. Dr. Crkvenac, with the support of the City of Krapina and Mayor Vilibald Sluga, he succeeds to the organization and operation of the hospital to an enviable level. Across the Austro-Hungarian Empire and Croatian, Hospitals Red Cross, had a significant role in caring for the wounded, injured and sick soldiers and civilians. Red Cross Hospital in Krapina, is an example of a well-organized hospital in the toughest conditions. Such an organization was not simple in its implementation, and left the valuable lessons and experience. PMID:27598958

  9. Hospital fundamentals.

    PubMed

    Althausen, Peter L; Hill, Austin D; Mead, Lisa

    2014-07-01

    Under the current system, orthopaedic trauma surgeons must work in some form of hospital setting as our primary service involves treatment of the trauma patient. We must not forget that just as a trauma center cannot exist without our services, we cannot function without their support. As a result, a clear understanding of the balance between physicians and hospitals is paramount. Historical perspective enables physicians and hospital personnel alike to understand the evolution of hospital-physician relationship. This process should be understood upon completion of this chapter. The relationship between physicians and hospitals is becoming increasingly complex and multiple forms of integration exist such as joint ventures, gain sharing, and co-management agreements. For the surgeon to negotiate well, an understanding of hospital governance and the role of the orthopaedic traumatologist is vital to success. An understanding of the value provided by the traumatologist includes all aspects of care including efficiency, availability, cost effectiveness, and research activities. To create effective and sustainable healthcare institutions, physicians and hospitals must be aligned over a sustained period of time. Unfortunately, external forces have eroded the historical basis for the working relationship between physicians and hospitals. Increased competition and reimbursement cuts, coupled with the increasing demands for quality, efficiency, and coordination and the payment changes outlined in healthcare reform, have left many organizations wondering how to best rebuild the relationship. The principal goal for the physician when partnering with a hospital or healthcare entity is to establish a sustainable model of service line management that protects or advances the physician's ability to make impactful improvements in quality of patient care, decreases in healthcare costs, and improvements in process efficiency through evidence-based practices and protocols. PMID

  10. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    ScienceCinema

    Moniz, Ernest [U.S. Energy Secretary

    2014-08-22

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of the research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.

  11. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    SciTech Connect

    Moniz, Ernest

    2014-02-03

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of the research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.

  12. Adapting the neurology area of the Gustavo Fricke Hospital

    NASA Astrophysics Data System (ADS)

    Ankelen, A.; González, S.; Aguirre, L.

    2007-11-01

    Within the framework of the subject Clinical Engineering taught at Hospital Dr. Gustavo Fricke of Viña del Mar Chile, we were assigned to undertake a detailed study on the quality of the electrical power main supply of the Neurology Department, on account of reported malfunctioning of some equipment used in this unit. The study results indicated that the problems occurred only in a device for auditory evoked potentials device and, contrary to what was expected, the problem was unrelated to the quality of the electrical main supply. It was also found that the cause for the problem was electromagnetic interference (EMI) emitted from the system's very own components. To solve the problem, we built a Faraday Cage for the signal-processing unit and increased the separating distance among the various system components. This approach enhanced system performance and significantly improved the recorded signals of patients. The solution adopted from this experience was suggested to others health care centers of our country that had been experiencing similar difficulties with the same type of medical equipment.

  13. Celebrating the Life and Legacy of Dr. John Hope Franklin

    ERIC Educational Resources Information Center

    Harris, Robert L., Jr.; Levering-Lewis, David; French, John D.; Wharton, Clifton R., Jr.

    2009-01-01

    Dr. John Hope Franklin chronicled the experiences of African-Americans like no one before him, forcing America to recognize Black history as American history. His contributions were innumerable and his impact was abiding. In celebration of his life and legacy, the authors profile the celebrated scholar and activist, Dr. John Hope Franklin.

  14. Dr. Irene Sänger-Bredt, a life for astronautics

    NASA Astrophysics Data System (ADS)

    Zaganescu, Nicolae-Florin

    2004-12-01

    Irene Bredt (b.1911 at Bonn) obtained her Doctorate in Physics in 1937; in the same year she became a scientific researcher at the German Research Center for Aviation at Trauen, led by Prof. Dr. Eugen Sänger. Soon, the young but efficient Dr. Irene Bredt became the first assistant of Dr. Sänger, who married her (1951). During 1973-1978, Dr. Bredt was in correspondence with Prof. Dr. Nikolae-Florin Zaganescu and helped him to familiarize the Romanian readers with Prof. Sänger's life and achievements. As for Dr. Bredt's life, she specified three main periods of her activity: 1937-1942, when she was researcher in charge of thermodynamic problems of liquid-fuelled rocket engines at Trauen 1942-1945, when she was Senior Researcher in charge of Ramjet in flight performances at Ainring, and also coauthored the Top Secret Technical report entitled 'A Rocket Engine for a Long-Range Bomber', which was finished in 1941 but edited only in 1944 the post world war II period, when she was Scientific Advisor or Director at various civil and military research institutes, universities, etc. Dr. Irene Sänger-Bredt helped her husband to develop many scientific theories like Ramjet thermodynamic theory, and photon rocket theory and also in establishing IAF and IAA. In 1970, Dr. Irene Sänger-Bredt was honored with 'Hermann Oberth Gold Medal' for her impressive scientific activity.

  15. Dr. Albert Carr--Science Educator 1930-2000

    ERIC Educational Resources Information Center

    Lopez, Leslie

    2013-01-01

    The very first issue of "Educational Perspectives" was published in October of 1962. Dr. Albert Carr wrote one of the inaugural essays on the topic of current developments in science education, and he went on to write several other articles for the journal. This article shares why Dr. Albert Carr's colleagues remember him for his…

  16. Dr. Wernher Von Braun near the mobile launcher.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. George Mueller, NASA associate administrator for manned space flight, and Dr. Wernher Von Braun (right), director of the Marshall Space Flight Center, are seen near the mobile launcher carrying a 363 foot tall Saturn V space launch vehicle as the rocket is rolled from the vehicle assembly building at KSC for its three mile trip to the launch pad.

  17. Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis

    NASA Technical Reports Server (NTRS)

    Lewis, Cathleen; Wright, Rebecca

    2012-01-01

    Dr. Cathleen Lewis was interviewed by Rebecca Wright during the presentation of an "Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis" on May 14, 2012. Topics included the care, size, and history of the spacesuit collection at the Smithsonian and the recent move to the state-of-the-art permanent storage facility at the Udvar-Hazy facility in Virginia.

  18. Dr. von Braun Touring the Johnson Space Center

    NASA Technical Reports Server (NTRS)

    1964-01-01

    This photograph is dated October 14, 1964, and shows Dr. von Braun, left, during a tour of the NASA Marned Spacecraft Center, now the Johnson Space Center. He is with Dr. J.P. Kuettner, center, from the Marshall Space Flight Center, and Warren J. North from the Manned Spacecraft Center.

  19. Dr. Shawn Mehlenbacher 2012 Wilder Silver Medal Recipient

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Dr. Shawn Mehlenbacher, Oregon State University, was awarded the 2012 Wilder Medal by the American Pomological Society for his contributions to hazelnut genetics and cultivar development. Dr. Mehlenbacher took over the leadership of the Oregon State University hazelnut breeding program in 1986 aft...

  20. Biotechnology Symposium - In Memoriam, the Late Dr. Allan Zipf

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A one-day biotechnology symposium was held at Alabama A&M University (AAMU), Normal, AL on June 4, 2004 in memory of the late Dr. Allan Zipf (Sept 1953-Jan 2004). Dr. Zipf was a Research Associate Professor at the Department of Plant and Soil Sciences, AAMU, who collaborated extensively with ARS/MS...

  1. Dr. von Braun with Governor Wallace and NASA Administrator Webb

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Governor of Alabama George Wallace (left), NASA Administrator James Webb and Marshall Space Flight Center (MSFC) Director Dr. von Braun during a tour of MSFC on June 8, 1965. Governor Wallace and Dr. Webb were at MSFC to witness the first test firing of a Saturn V Booster, along with members of the Alabama legislature and press reporters.

  2. Dr. von Braun, Governor Wallace and NASA Administrator Webb

    NASA Technical Reports Server (NTRS)

    1965-01-01

    In this photograph are Alabama Governor George Wallace (left), Marshall Space Flight Center Dr. Wernher von Braun (Center) and NASA Administrator James Webb (right). Governor Wallace and Dr. Webb were at MSFC to witness the first test firing of a Saturn V Booster, along with members of the Alabama legislature and press reporters.

  3. SDSS DR7 WHITE DWARF CATALOG

    SciTech Connect

    Kleinman, S. J.; Nitta, A.; Kepler, S. O.; Pelisoli, Ingrid; Pecanha, Viviane; Costa, J. E. S.; Koester, D.; Krzesinski, J.; Dufour, P.; Lachapelle, F.-R.; Bergeron, P.; Yip, Ching-Wa; Harris, Hugh C.; Eisenstein, Daniel J.; Althaus, L.; Corsico, A.

    2013-01-15

    We present a new catalog of spectroscopically confirmed white dwarf stars from the Sloan Digital Sky Survey (SDSS) Data Release 7 spectroscopic catalog. We find 20,407 white dwarf spectra, representing 19,712 stars, and provide atmospheric model fits to 14,120 DA and 1011 DB white dwarf spectra from 12,843 and 923 stars, respectively. These numbers represent more than a factor of two increase in the total number of white dwarf stars from the previous SDSS white dwarf catalogs based on DR4 data. Our distribution of subtypes varies from previous catalogs due to our more conservative, manual classifications of each star in our catalog, supplementing our automatic fits. In particular, we find a large number of magnetic white dwarf stars whose small Zeeman splittings mimic increased Stark broadening that would otherwise result in an overestimated log g if fit as a non-magnetic white dwarf. We calculate mean DA and DB masses for our clean, non-magnetic sample and find the DB mean mass is statistically larger than that for the DAs.

  4. Portrait of Dr Michael G. Hanna, Jr

    PubMed Central

    Hanna Jr, Michael

    2014-01-01

    While a PhD candidate, doing my thesis at the Oak Ridge National Laboratory, Biology Division under Dr. Charles Congdon, my introduction to the immune response was studying graft vs. host (GVH) disease as a consequence of bone marrow transplantation in mice. The sequalae of GVH was impressive, and demonstrated the potential of negative clinical consequences of the immune system. The idea of harnessing this immunological phenomena in cancer therapy was appealing even in the late 1960s. The problem was that at the time T-cells as a component of the immune system were identified but not defined. We moved to soluble antigen stimulation in mice and recognized and described the post antigen stimulation changes in lymphatic tissue germinal centers during the first 48 h after the induction of the humoral immune response. We described the extracellular localization of soluble antigens on the surface of dendritic reticular cells of the stroma, directing a response of B-cells to produce antibody against non-self. The ensuing reaction was the rapid proliferation of B-cells toward antibody secreting plasma cells. PMID:25424782

  5. Dr. Otto "Tiger" Freer: inventor and innovator.

    PubMed

    Chittiboina, Prashant; Connor, David E; Nanda, Anil

    2012-08-01

    Every neurosurgeon develops his or her own standard approach to common intracranial pathologies in terms of the order in which different stages are performed and which instruments are used to perform individual tasks. The majority of the basic steps in performing a craniotomy are learned through repetition and practice during residency training. Significant amounts of energy are devoted to mastering technical skills and developing an operative rhythm. What often receives little attention is the historical origin of the instruments that make the work possible. The Freer elevator represents a particularly interesting example. To people unfamiliar with the accomplishments of turn-of-the-century laryngologist Otto "Tiger" Freer, it can be assumed that the name of the instrument in one's hand is simply named for what it can do, that is, to "free" the nasal mucosa from the bony and cartilaginous septum during the transsphenoidal approach. The technique this master surgeon spent his life and career perfecting is now repeated almost daily by skull base neurosurgeons approaching pathologies from the inferior frontal lobe to the foramen magnum. In reviewing his life and work, the authors of this paper discovered an interesting creative process that led to the design of the eponymous instrument. Additionally, they discovered important advances toward the development of the transnasal approach and in our understanding of the anterior skull base. They present a historical perspective on the life and accomplishments of Dr. Freer and the ubiquitous surgical instrument that he invented and popularized. PMID:22853830

  6. Carbon Stars from LAMOST DR2 Data

    NASA Astrophysics Data System (ADS)

    Ji, Wei; Cui, Wenyuan; Liu, Chao; Luo, Ali; Zhao, Gang; Zhang, Bo

    2016-09-01

    In this work, we present the new catalog of carbon stars from the LAMOST DR2 catalog. In total, 894 carbon stars are identified from multiple line indices measured from the stellar spectra. We are able to identify the carbon stars by combining the CN bands in the red end with C2 and other lines. Moreover, we also classify the carbon stars into spectral sub-types of C–H, C–R, and C–N. These sub-types show distinct features in the multi-dimensional line indices, implying that in the future they can be used to identify carbon stars from larger spectroscopic data sets. While the C–N stars are clearly separated from the others in the line index space, we find no clear separation between the C–R and C–H sub-types. The C–R and C–H stars seem to smoothly transition from one to another. This may hint that the C–R and C–H stars may not be different in their origins, instead their spectra look different because of different metallicities. Due to the relatively low spectral resolution and lower signal-to-noise ratio, the ratio of 12C/13C is not measured and thus the C–J stars are not identified.

  7. Dr. Hall and the work cure.

    PubMed

    Reed, Kathlyn L

    2005-01-01

    Herbert James Hall, MD (1870-1923), was a pioneer in the systematic and organized study of occupation as therapy for persons with nervous and mental disorders that he called the "work cure." He began his work in 1904 during the early years of the Arts and Crafts Movement in the United States. His primary interest was the disorder neurasthenia, a condition with many symptoms including chronic fatigue, stress, and inability to work or perform everyday tasks. The prevailing treatment of the day was absolute bed rest known as the "rest cure." Hall believed that neurasthenia was not caused by overwork but by faulty living habits that could be corrected through an ordered life schedule and selected occupations. He identified several principles of therapy that are still used today including graded activity and energy conservation. Dr. Adolph Meyer credits Hall for organizing the ideas on the therapeutic use of occupation (Meyer, 1922). Hall also provided the name American Occupational Therapy Association for the professional organization and served as the fourth president. For his many contributions to the profession Hall deserves to be recognized as a major contributor to the development and organization of occupational therapy. PMID:23927746

  8. Hospital Hints

    MedlinePlus

    ... Division of Geriatrics and Clinical Gerontology Division of Neuroscience FAQs Funding Opportunities Intramural Research Program Office of ... have to spend the night in the hospital. Learning more about what to expect and about people ...

  9. Resistance movement: the antibiotic crisis in hospitals.

    PubMed

    Goldmann, D A

    1997-01-01

    The near-miraculous healing power of antibiotic is being undermined by the rapid evolution of drug-resistant bacteria. The costs, in human and economic terms, could be staggering for all caregivers and patients, but especially for institutional providers like hospitals. In an article adapted from the Journal of the American Medical Association, Dr. Goldmann explains why antibiotic resistance is a crisis and how the danger can be mitigated. PMID:10166180

  10. Hospital philanthropy.

    PubMed

    Smith, Dean G; Clement, Jan P

    2013-01-01

    It remains an open question whether hospital spending on fundraising efforts to garner philanthropy is a good use of funds. Research and industry reports provide conflicting results. We describe the accounting and data challenges in analysis of hospital philanthropy, which include measurement of donations, measurement of fundraising expenses, and finding the relationships among organizations where these cash flows occur. With these challenges, finding conflicting results is not a surprise. PMID:23614267

  11. [DR. SHOSHANA SZKOP-FRENKIEL: THE FIRST FEMALE PLASTIC SURGEON IN ISRAEL].

    PubMed

    Shehory-Rubin, Zipora

    2015-11-01

    In the history of Israeli medicine, Dr. Shoshana Szkop-Frenkiel is regarded as the first plastic surgeon in the country and among the founders of the profession of plastic surgery. This article describes the long road she traveled, from her acceptance into medical studies in Vilna--at a time when the entry of any woman to the faculty of medicine was strictly limited and of Jewish women in particular; her emigration to Eretz Israel and her struggles as she underwent training in internal medicine at the "Hadassah" Hospital in Tel-Aviv, when she was denied training as a surgeon; and up to the moment she was accepted by the plastic surgery unit of the Tel Hashomer Hospital and became the first such female practitioner in Israel. Dr. Shoshana Szkop-Frenkiel thus fulfilled a childhood dream to become a surgeon at a time when women were excluded from surgery on the grounds that it called for "male" characteristics. This article is intended to illustrate the character of a female doctor pursuing a career in surgery during the time of the British Mandate, to illuminate her professional travails in Israel, and to emphasize her important contribution in the field. PMID:26821508

  12. Why can Sensitization by a HLA-DR2 Mismatch lead to Antibodies that react also with HLA-DR1?

    PubMed Central

    Marrari, Marilyn; Duquesnoy, Rene J.

    2009-01-01

    HLAMatchmaker is a matching algorithm that can be used to characterize antibodies specific for structurally defined epitopes. Under auspices of the 15th International Histocompatibility Workshop we are conducting a multilaboratory collaborative project to characterize these epitopes and also determine how often they induce specific antibodies in patients with rejected kidney transplants. This report addresses the reactivity of post-allograft nephrectomy sera tested for DRB antibodies with Luminex assays using single alleles. This analysis was done for 19 informative kidney transplant cases contributed by 13 laboratories worldwide. There were 11 cases with a single DR2 mismatch (DR15 or DR16) and 9 of them (82%) showed antibodies with both DR2 and DR1. Although these antigens might share an epitope recognized by these antibodies, this interpretation is incorrect. The HLAMatchmaker analysis offers a clearly different explanation that involves antibodies induced by DR51 which commonly associates with DR2. DR51 has an epitope defined by the 96EV eplet which is also present on DR1 but no other DR antigen. This means that the reactivity with DR51 and DR1 reflects the presence of 96EV-specific antibodies. Conversely, we analyzed eight patients sensitized by a single DR1 mismatch which has no associated DR51. All of them reacted also with DR51 and this could only be explained with antibodies against the shared 96EV eplet. These findings demonstrate that 96EV represents a highly immunogenic epitope that can induce cross-sensitization between antigens encoded by the different DRB loci and also that DR51 is important in determining DRB mismatch acceptability of potential donors. This analysis has also demonstrated that antibody responses are restricted to a few epitopes on these immunizing DR antigens. For DR2 they are 142M3 (unique for DR2), 71QAA (shared with DB5*02) and 96QV (shared with DR10). DR51 mismatches appear to have three immunogenic eplets: 96EV (shared with DR1

  13. The decisive decade. Interview: Dr. Nafis Sadik.

    PubMed

    1989-01-01

    The interview with Dr. Nafis Sadik, Director of the UN Family Planning Association (UNFPA), involved questions about the Fund's major achievements, the effect of withdrawal of US funds on UNFPA programs, the role of UNFPA in bridging environmental, population, and development objectives as stated in the Bruntland Commission initiatives, awareness building, the role of UNFPA in dealing with resource deficits in countries with high growth populations, the seriousness of the 1990s decade as critical to the future. and UNFPA's priorities for the next 10 years. The Fund's accomplishments are in getting political systems to recognize as an important part of development, in broadening the concept of population to include quality of life and spatial distribution and growth, and in obtaining funding to continue operating without US funds. The US withdrawal of funds has affected UNFPA's funding in Africa since 1985. UNFPA is actively working to help other agencies integrate FP into conservation strategies, and to consider the education of women and provision for FP information in a variety of programs. Sustainable development must occur at the grass roots level, or from the ground up. Programs must be implemented with an understanding of local needs and desires and with cultural sensitivity. A review of findings over 20 years led to an understanding that many countries had no strategy or plans for population programs even with a lot of development assistance, and programs were transplanted without consideration of local needs. UNFPA is not urging that national development strategies must incorporate population planning, and to target education to young people who will soon be entering reproductive ages during the decade ahead. Governments have begun to recognize that the next 10 years will determine the future, and population does affect the crisis of resources. UNFPA's priorities are to the education of youth, to design special curricula in schools for educating about

  14. Molecular diversity of HLA-DR4 haplotypes.

    PubMed Central

    Gregersen, P K; Shen, M; Song, Q L; Merryman, P; Degar, S; Seki, T; Maccari, J; Goldberg, D; Murphy, H; Schwenzer, J

    1986-01-01

    Complementary DNA (cDNA) clones encoding beta chains of the DR and DQ regions and alpha chains of the DQ region were isolated and sequenced from four homozygous DR4 cell lines of different HLA-D types: GM3103(Dw4), FS(Dw10), BIN(Dw14), and KT3(Dw15). When compared with each other and with a previously published sequence from a DR4 (Dw13 cell line), the variability of DR beta 1 gene products is generally restricted to the region around amino acid position 70, with an additional polymorphism at position 86. Many of these differences, including an unusual amino acid substitution at position 57 in the Japanese cell line KT3(Dw15), may be due to gene conversion events from the DR beta 2 or DX beta genes. In contrast, DR beta 2 molecules are identical in Dw15, Dw10, and Dw4 cell lines. DQ beta chains isolated from GM3103(Dw4), FS(Dw10), and BIN40(Dw14) are also identical. However, the DQ beta sequence from cell line KT3(Dw15) differs substantially from all other previously reported DQ beta alleles, consistent with its serological designation, DQ "blank." The first domain sequences of DQ alpha chains were identical in all four cell lines. The data suggest that relatively circumscribed amino acid changes in the DR beta 1 molecule are responsible for the HLA-D typing differences between some haplotypes. PMID:3458223

  15. Evidence for a new HLA class II determinant present on cells from HLA-DR1 and/or -DR4 individuals.

    PubMed

    Lepage, V; Alcalay, D; Douay, C; Mallet, C; Loiseau, P; Degos, L; Colombani, M; Colombani, J

    1985-02-01

    Evidence for a new HLA class II specificity is presented. It is recognized by LE serum, which reacts with most DR1 and/or DR4 individuals (r = 0.86). Its frequency in the French population is 0.33. Absorption-elution experiments showed that the serum reactivity was not due to a mixture of anti-DR1 and anti-DR4 antibodies, but to a single antibody population which could be absorbed on and eluted from both DR1(+) or DR4(+) cells. LE specificity seemed to be expressed on DR but not on DQ molecules since the serum reacted with and could be absorbed by DR+,DQw- cells; it did not react with a DR-,DQw+ mutant cell, but did react with the DR+,DQw+ parental cell. The relationship between LE specificity and MC1 and Te23 specificities remains to be determined. PMID:2581334

  16. [Laennec Hospital].

    PubMed

    Dauphin, A; Mazin-Deslandes, C

    2000-01-01

    When the Laennec Hospital of Paris closed, after 366 years of activities for the patients, the articles about the circumstances of the foundation and the main stapes of the institution which became an very famous university hospital it present the available information of the history of the apothecaries, of the "gagnants-maitrise", pharmacists and the pharmacy's interns who succeeded themselves to create and dispense the medicaments necessary to the patients hospitalized or welcomed in ambulatory. It describes the evolution of the places, of the material, of forms, of the organization, of the medicaments and of the missions of what became the Pharmacy department after the recent individualization of the biological analysis in the biochemistry. PMID:11625687

  17. Glaucoma: Eye-to-Eye with Dr. Rachel Bishop

    MedlinePlus

    ... of this page please turn JavaScript on. Feature: Glaucoma Eye-to-Eye with Dr. Rachel Bishop Past ... nerves are pale and cupped—signs of advanced glaucoma. Yet the patient wasn't aware of any ...

  18. NES Live Video Chat: Dr. John C. Mather

    NASA Video Gallery

    NES welcomed Nobel Prize winner Dr. John C. Mather for a video webchat on May 17, 2011. He spoke about the James Webb Space Telescope and how it gives us a look into the past to see how galaxies ha...

  19. GOES-R with Dr. Kathy Sullivan and Tim Samaras

    NASA Video Gallery

    This short video features highlights from a live Nationwide broadcast that took place on April 3, 2012, from the studio of NASA Goddard TV. NOAA’s Deputy Administrator and Chief Scientist Dr. Ka...

  20. Grantee Spotlight: Dr. Kolawole Okuyemi - Improving Cervical Cancer Screening Attitudes

    Cancer.gov

    Dr. Kolawole Okuyumi is studying cervical cancer screening attitudes and behaviors of African immigrants and refugees in Minnesota, and introducing “cancer” and “cervix” to their everyday vocabulary.

  1. 74. ARAII. Dr. William Zinn of combustion engineering company and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    74. ARA-II. Dr. William Zinn of combustion engineering company and others at controls of SL-1. August 8, 1959. Ineel photo no. 59-4109. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  2. Academic Hospitality

    ERIC Educational Resources Information Center

    Phipps, Alison; Barnett, Ronald

    2007-01-01

    Academic hospitality is a feature of academic life. It takes many forms. It takes material form in the hosting of academics giving papers. It takes epistemological form in the welcome of new ideas. It takes linguistic form in the translation of academic work into other languages, and it takes touristic form through the welcome and generosity with…

  3. Hospitality Management.

    ERIC Educational Resources Information Center

    College of the Canyons, Valencia, CA.

    A project was conducted at College of the Canyons (Valencia, California) to initiate a new 2-year hospitality program with career options in hotel or restaurant management. A mail and telephone survey of area employers in the restaurant and hotel field demonstrated a need for, interest in, and willingness to provide internships for such a program.…

  4. Dr. Peter Emil Becker and the Third Reich.

    PubMed

    Hill, Frank

    2013-08-01

    In 1985 the physician after whom Becker Muscular Dystrophy is named, German neurologist Dr. Peter Emil Becker (1908-2000), published an autobiographical article in the American Journal of Medical Genetics in which he disavowed any association with the Nazi Party. A closer look at the evidence, however, suggests otherwise. Review of war records and related sources raise concern for Dr. Becker's affiliation with the Nazi Party and his contributions to its ideology. PMID:23813666

  5. Dr Pugh and the myth of the illicit still.

    PubMed

    Paull, J D

    2014-07-01

    In her valuable history of the arrival of the news of etherisation in Australia and its implementation by many doctors and dentists, titled One Grand Chain, the late Dr Gwen Wilson asserted that the dentist and the doctor who pioneered etherisation in Australia, "Belisario and Pugh, …were charged by the authorities with possession of an illicit still." This paper examines the evidence for the truth or otherwise of this assertion, in relation to Dr Pugh. PMID:25196958

  6. Dr. Wernher Von Braun at the launch of Apollo 11.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Mission officials relax, all smiles, a few moments after the successful launch of the Apollo 11 spacecraft by Saturn V vehicle AS-506. Relieved of the tension of waiting through the countdown are (left to right) Charles W. Matthews, NASA deputy associate administrator for manned space flight; Dr. Wernher Von Braun, Director of the Marshall Space Flight Center; Dr. George E. Meuller, NASA associate administrator for manned spaceflight, and Lt. General Samuel C. Phillips, director of the Apollo program.

  7. Dr. von Braun at 'Wernher von Braun Day' Celebration

    NASA Technical Reports Server (NTRS)

    1970-01-01

    In 1970 Marshall Space Flight Center (MSFC) Director Dr. Wernher von Braun (right) was reassigned to NASA Headquarters to serve as Deputy Associate Administrator for Plarning. Prior to his transfer, Dr. von Braun was honored for his career in Huntsville, Alabama, with the celebration of 'Wernher von Braun Day.' Among those participating were Alabama Governor Albert Brewer (left) and Alabama Senator John Sparkman (center). (Courtesy of Huntsville/Madison County Public library)

  8. Dr-FtsA, an Actin Homologue in Deinococcus radiodurans Differentially Affects Dr-FtsZ and Ec-FtsZ Functions In Vitro

    PubMed Central

    Modi, Kruti; Misra, Hari S.

    2014-01-01

    The Deinococcus radiodurans genome encodes homologues of divisome proteins including FtsZ and FtsA. FtsZ of this bacterium (Dr-FtsZ) has been recently characterized. In this paper, we study FtsA of D. radiodurans (Dr-FtsA) and its involvement in regulation of FtsZ function. Recombinant Dr-FtsA showed neither ATPase nor GTPase activity and its polymerization was ATP dependent. Interestingly, we observed that Dr-FtsA, when compared with E. coli FtsA (Ec-FtsA), has lower affinity for both Dr-FtsZ and Ec-FtsZ. Also, Dr-FtsA showed differential effects on GTPase activity and sedimentation characteristics of Dr-FtsZ and Ec-FtsZ. For instance, Dr-FtsA stimulated GTPase activity of Dr-FtsZ while GTPase activity of Ec-FtsZ was reduced in the presence of Dr-FtsA. Stimulation of GTPase activity of Dr-FtsZ by Dr-FtsA resulted in depolymerization of Dr-FtsZ. Dr-FtsA effects on GTPase activity and polymerization/depolymerisation characteristics of Dr-FtsZ did not change significantly in the presence of ATP. Recombinant E. coli expressing Dr-FtsA showed cell division inhibition in spite of in trans expression of Dr-FtsZ in these cells. These results suggested that Dr-FtsA, although it lacks ATPase activity, is still functional and differentially affects Dr-FtsZ and Ec-FtsZ function in vitro. PMID:25551229

  9. Remaining Sites Verification Package for 132-DR-1, 1608-DR Effluent Pumping Station, Waste Site Reclassification Form 2005-035

    SciTech Connect

    R. A. Carlson

    2005-09-22

    Radiological characterization, decommissioning and demolition of the 132-DR-1 site, 1608-DR Effluent Pumping Station was performed in 1987. The current site conditions achieve the remedial action objectives and the corresponding remedial action goals established in the Remaining Sites ROD. Residual concentrations support future land uses that can be represented by a rural-residential scenario and pose no threat to groundwater or the Columbia River based on RESRAD modeling.

  10. Seoul National University Bundang Hospital's Electronic System for Total Care

    PubMed Central

    Yoo, Sooyoung; Lee, Kee Hyuck; Lee, Hak Jong; Ha, Kyooseob; Lim, Cheong; Chin, Ho Jun; Yun, Jonghoar; Cho, Eun-Young; Chung, Eunja; Baek, Rong-Min; Chung, Chin Youb; Wee, Won Ryang; Lee, Chul Hee; Lee, Hai-Seok; Byeon, Nam-Soo

    2012-01-01

    Objectives Seoul National University Bundang Hospital, which is the first Stage 7 hospital outside of North America, has adopted and utilized an innovative and emerging information technology system to improve the efficiency and quality of patient care. The objective of this paper is to briefly introduce the major components of the SNUBH information system and to describe our progress toward a next-generation hospital information system (HIS). Methods SNUBH opened in 2003 as a fully digital hospital by successfully launching a new HIS named BESTCare, "Bundang hospital Electronic System for Total Care". Subsequently, the system has been continuously improved with new applications, including close-loop medication administration (CLMA), clinical data warehouse (CDW), health information exchange (HIE), and disaster recovery (DR), which have resulted in the achievement of Stage 7 status. Results The BESTCare system is an integrated system for a university hospital setting. BESTCare is mainly composed of three application domains: the core applications, an information infrastructure, and channel domains. The most critical and unique applications of the system, such as the electronic medical record (EMR), computerized physician order entry (CPOE), clinical decision support system (CDSS), CLMA, CDW, HIE, and DR applications, are described in detail. Conclusions Beyond our achievement of Stage 7 hospital status, we are currently developing a next-generation HIS with new goals of implementing infrastructure that is flexible and innovative, implementing a patient-centered system, and strengthening the IT capability to maximize the hospital value. PMID:22844650

  11. Type 1 Diabetes in the Spanish Population: additional factors to Class II HLA-DR3 and -DR4

    PubMed Central

    Urcelay, Elena; Santiago, José L; de la Calle, Hermenegildo; Martínez, Alfonso; Méndez, Julián; Ibarra, José M; Maluenda, Carlos; Fernández-Arquero, Miguel; de la Concha, Emilio G

    2005-01-01

    Background The Major Histocompatibility Complex is the main genetic contributor to susceptibility to type 1 diabetes (T1D); genome-wide scans have consistently mapped increased predisposition to this region. The highest disease risk has been associated with HLA-DR3 and HLA-DR4. In particular, the DR3-positive ancestral haplotype 18.2 was reported as highly diabetogenic. We aimed to corroborate whether this haplotype increases the susceptibility conferred by the DQ2-DR3 alleles in a Mediterranean population. We also searched for additional susceptibility factors to the classic DQ2-DR3 and DQ8-DR4. Results Genetic MHC markers were analysed in a case-control study with 302 T1D patients and 529 ethnically matched controls. DR3-TNFa1b5 carrier rate was significantly higher in DR3-positive heterozygous T1D patients than in DR3-positive heterozygous controls (p = 0.0019; odds ratio OR [95% confidence interval CI] = 2.26 [1.3–3.93]). This data was confirmed analysing the allelic frequency, which includes the information corresponding to the DR3-homozygous individuals (p = 0.001; OR = 2.09) and by using the Arlequin software to check the DR3-positive haplotypes (p = 0.004;OR = 1.93). The present results provide strong evidence of a second susceptibility region in the ancestral haplotype 18.2 in the Spanish population. Moreover, we searched for T1D susceptibility factors in addition to the MHC classical ones, within the DR2-DQ6/DR3-DQ2/DR4-DQ8 negative population. Several genetic markers in both MHC class II (DQA1*0101-DQB1*0501 [p = 0.007;OR = 2.81], DQA1*0201-DQB1*0202 [p = 0.03; OR = 2.35]) and III (TNFa2b1 [p = 0.01 OR = 2.74], BAT-2*2 [p = 0.004; OR = 3.19]) were found. These different alleles associated with T1D were not independent and we observed linkage disequilibrium among them leading us to describe two new risk haplotypes (DQA1*0101-DQB1*0501-TNFa2b1 and DQA1*0201-DQB1*0202- BAT-2*2). Finally, we studied a T1D susceptibility/protection marker located in

  12. Residential therapy. Hospitals take on finding housing for homeless patients, hoping to reduce readmissions, lower costs.

    PubMed

    Evans, Melanie

    2012-09-24

    As they grapple with containing the cost of caring for patients who frequently return to the ER or hospital for care, some hospitals are trying a new route: housing. In San Francisco, plans are under way to house 50 homeless patients. "Hospitalization is a failure of the medical system. It means that the condition has gotten so out of control that someone is at risk of life or limb," says Dr. Kelly Pfeifer, left, of the San Francisco Health Plan. PMID:23163192

  13. One-stop shop for care. Hospital ERs seeing increase in patients, capital.

    PubMed

    Kutscher, Beth; Selvam, Ashok

    2013-05-27

    Hospital emergency room departments are increasingly becoming a portal for patients to get care quickly. And hospitals are responding by transforming their operations. When Dr. Rich Zane, left, arrived last year as chair of the University of Colorado Hospital's emergency medicine department, the Aurora facility's ER was operating under "a process that's predicated on 1960s medicine and we're practicing it in 2013," he says. PMID:23951587

  14. The development of a specialty: an interview with Dr. Mark C. Rogers, a pioneering pediatric intensivist.

    PubMed

    Mai, Christine L; Firth, Paul G; Ahmed, Zulfiqar; Rodriguez, Samuel; Yaster, Myron

    2014-09-01

    Dr. Mark C. Rogers (1942-), Professor of Anesthesiology, Critical Care Medicine, and Pediatrics at the Johns Hopkins University, was recruited by the Department of Pediatrics at Johns Hopkins Hospital in 1977 to become the first director of its pediatric intensive care unit. After the dean of the medical school appointed him to chair the Department of Anesthesia in 1979, Rogers changed the course and culture of the department. He renamed it the Department of Anesthesiology and Critical Care Medicine, and developed a long-term strategy of excellence in clinical care, research, and education. However, throughout this period, he never lost his connection to pediatric intensive care. He has made numerous contributions to pediatric critical care medicine through research and his authoritative textbook, Rogers' Textbook of Pediatric Intensive Care. He established a training programme that has produced a plethora of leaders, helped develop the pediatric critical care board examination, and initiated the first World Congress of Pediatric Intensive Care. Based on a series of interviews with Dr. Rogers, this article reviews his influential career and the impact he made on developing pediatric critical care as a specialty. PMID:25065470

  15. DR with a DSLR: Digital Radiography with a Digital Single-Lens Reflex camera

    PubMed Central

    Fan, Helen; Durko, Heather L.; Moore, Stephen K.; Moore, Jared; Miller, Brian W.; Furenlid, Lars R.; Pradhan, Sunil; Barrett, Harrison H.

    2010-01-01

    An inexpensive, portable digital radiography (DR) detector system for use in remote regions has been built and evaluated. The system utilizes a large-format digital single-lens reflex (DSLR) camera to capture the image from a standard fluorescent screen. The large sensor area allows relatively small demagnification factors and hence minimizes the light loss. The system has been used for initial phantom tests in urban hospitals and Himalayan clinics in Nepal, and it has been evaluated in the laboratory at the University of Arizona by additional phantom studies. Typical phantom images are presented in this paper, and a simplified discussion of the detective quantum efficiency of the detector is given. PMID:21516238

  16. Screening for Depression in Hospitalized Pediatric Patients

    PubMed Central

    ESMAEELI, Mohammad-Reza; ERFANI SAYAR, Reza; SAGHEBI, Ali; ELMI, Saghi; RAHMANI, Shagheyegh; ELMI, Sam; RABBANI JAVADI, Akram

    2014-01-01

    Objective In chronically ill children who are hospitalized, many mood changes occur. For example, in children with cancer or renal failure, prolonged hospitalization and chemotherapy can lead to depression. With the improved survival of childhood malignancies, the effect of treatment on child’s psychosocial well-being becomes increasingly relevant. In this study, we examined the prevalence of depression in hospitalized children with chronic and acute conditions in Dr Sheikh Pediatrics Hospital in Mashhad. Materials & Methods After receiving the approval from the Ethics Committee of Mashhad University of Medical Sciences, we did this cross-sectional descriptive study, from April to June 2012 in Dr Sheikh Pediatric Hospital in Mashhad. Ninety children, between 8 to 16 years, were screened for depression. The sampling method was census. Children with a history of depressive or other mental disorders were excluded. Three groups of children (children with chronic renal disease, malignancy, and acute disease) were evaluated for depression using standard Children Depression Inventory Questionnaire (CDI). Two specifically trained nurses filled out the questionnaires at patients’ bedside under the supervision of a psychiatrist. Depression scores were then analyzed by SPSS software. Results Of 90 children, 43(47.7%) were male and 47(52.2%) were female. The Children’s mean age was 11±2.3 years, and the mean length of hospitalization was 8±5.3 days. Depression was detected in various degrees in 63% of patients (N=57), and 36.6% of children (N=32) had no symptoms of depression. Severe depression was not seen in any of the patients with acute illness. More than half of patients with cancer and chronic kidney disease had moderate to severe depression. There was a significant statistical relationship between the duration of illness and severity of depression. There was also a significant correlation between severity of depression and frequency of hospitalization. Children

  17. A periodontal case report by Dr. S.L. Clemens.

    PubMed

    Maloney, W J

    2010-07-01

    Mark Twain provides a humorous and insightful look into the origins of periodontal therapy and anesthesia in "Happy Memories of the Dental Chair". The main character of this story is Dr. John Riggs, the father of periodontics. Dr. Horace Wells, a pioneer in the field of anesthesia, also appears in the story. Twain presents his autobiographical experiences with dentistry in his literary work in a form that can be seen to be similar to a case report in a professional dental journal. PMID:20400720

  18. Study of photoluminescence properties of thin films DR1

    NASA Astrophysics Data System (ADS)

    Herman, Ulya, Naily

    2015-09-01

    Fabrication of thin films DR1 have been carried out by the EFA-PDF (Electric Field-Assisted Physical Vapor Deposition) method to obtain films with parallel dipole arrangement. Molecular deposition process is performed by applying an electric field that is placed between the substrate ITO (Indium Tin Oxide) and copper mesh. The resulting films were characterized by using a spectrofluorometer. Analysis of the emission spectrum, indicate that DR1 molecules in the film oriented perpendicular to the substrate and arranged in parallel order (H-aggregate). As an effect, the peak of the emission spectrum appears stronger along with the increase of electric field strength.

  19. Study of photoluminescence properties of thin films DR1

    SciTech Connect

    Herman, Ulya, Naily

    2015-09-30

    Fabrication of thin films DR1 have been carried out by the EFA-PDF (Electric Field-Assisted Physical Vapor Deposition) method to obtain films with parallel dipole arrangement. Molecular deposition process is performed by applying an electric field that is placed between the substrate ITO (Indium Tin Oxide) and copper mesh. The resulting films were characterized by using a spectrofluorometer. Analysis of the emission spectrum, indicate that DR1 molecules in the film oriented perpendicular to the substrate and arranged in parallel order (H-aggregate). As an effect, the peak of the emission spectrum appears stronger along with the increase of electric field strength.

  20. Social contract of academic medical centres to the community: Dr Howard Atwood Kelly (1858-1943), a historical perspective.

    PubMed

    Allen, Paul

    2016-05-01

    Academic medical centres have traditionally been bastions of teaching and research. Outreach to the community at large and involvement in community affairs have sometimes been lacking in the overall mission and activities of academic medical centres. This paper provides an historical perspective first on the numerous achievements of a physician and surgeon and then on the topic of involvement in community affairs by reviewing the many contributions of America's pioneer gynaecological surgeon and one of the four physician founders of the Johns Hopkins Hospital and School of Medicine in 1889 - Dr Howard Atwood Kelly. PMID:24906403

  1. Sequence and evolution of HLA-DR7- and -DRw53-associated. beta. -chain genes

    SciTech Connect

    Young, J.A.T.; Wilkinson, D.; Bodmer, W.F.; Trowsdale, J.

    1987-07-01

    cDNA clones representing products of the DR7 and DRw53 ..beta..-chain genes were isolated from the human B-lymphoblastoid cell line MANN (DR7, DRw53, DQw2, DPw2). The DRw53..beta.. sequence was identical to a DRw53..beta.. sequence derived from cells with a DR4 haplotype. In contrast, the DR7..beta.. sequence was as unrelated to DR4..beta.. sequence as it was to other DR..beta..-related genes, except at the 3'-untranslated region. These results suggest that the DR7 and DR4 haplotypes may have been derived relatively recently from a common ancestral haplotype and that the DR4 and DR7 ..beta..-chain genes have undergone more rapid diversification in the ..beta..1 domains, most probably as a result of natural selection, than have the DRw53..beta..-chain genes. Short tracts of sequence within the DR7 and DRw53 ..beta..1 domains were shared with other DR..beta.. sequences, indicating that exchanges of genetic information between ..beta..1 domains of DR..beta..-related genes have played a part in their evolution. Serological analysis of mouse L-cell transfectants expressing surface HLA-DR7 molecules, confirmed by antibody binding and allelic sequence comparison, identified amino acid residues that may be critical to the binding of a monomorphic DR- and CP-specific monoclonal antibody.

  2. Genomic evaluation of HLA-DR3+ haplotypes associated with type 1 diabetes.

    PubMed

    Kumar, Neeraj; Kaur, Gurvinder; Tandon, Nikhil; Kanga, Uma; Mehra, Narinder K

    2013-04-01

    We have defined three sets of HLA-DR3(+) haplotypes that provide maximum risk of type 1 disease development in Indians: (1) a diverse array of B8-DR3 haplotypes, (2) A33-B58-DR3 haplotype, and (3) A2-B50-DR3 occurring most predominantly in this population. Further analysis has revealed extensive diversity in B8-DR3 haplotypes, particularly at the HLA-A locus, in contrast to the single fixed HLA-A1-B8-DR3 haplotype (generally referred to as AH8.1) reported in Caucasians. However, the classical AH8.1 haplotype was rare and differed from the Caucasian counterpart at multiple loci. In our study, HLA-A26-B8-DR3 (AH8.2) was the most common B8-DR3 haplotype constituting >50% of the total B8-DR3 haplotypes. Further, A2-B8-DR3 contributed the maximum risk (RR = 48.7) of type 1 diabetes, followed by A2-B50-DR3 (RR = 9.4), A33-B58-DR3 (RR = 6.6), A24-B8-DR3 (RR = 4.5), and A26-B8-DR3 (RR = 4.2). Despite several differences, the disease-associated haplotypes in Indian and Caucasian populations share a frozen DR3-DQ2 block, suggesting a common ancestor from which multiple haplotypes evolved independently. PMID:23387390

  3. STATISTICAL STUDY OF 2XMMi-DR3/SDSS-DR8 CROSS-CORRELATION SAMPLE

    SciTech Connect

    Zhang Yanxia; Zhou Xinlin; Zhao Yongheng; Wu Xuebing

    2013-02-01

    Cross-correlating the XMM-Newton 2XMMi-DR3 catalog with the Sloan Digital Sky Survey (SDSS) Data Release 8, we obtain one of the largest X-ray/optical catalogs and explore the distribution of various classes of X-ray emitters in the multidimensional photometric parameter space. Quasars and galaxies occupy different zones while stars scatter in them. However, X-ray active stars have a certain distributing rule according to spectral types. The earlier the type of stars, the stronger its X-ray emitting. X-ray active stars have a similar distribution to most stars in the g - r versus r - i diagram. Based on the identified samples with SDSS spectral classification, a random forest algorithm for automatic classification is performed. The result shows that the classification accuracy of quasars and galaxies adds up to more than 93.0% while that of X-ray emitting stars only amounts to 45.3%. In other words, it is easy to separate quasars and galaxies, but it is difficult to discriminate X-ray active stars from quasars and galaxies. If we want to improve the accuracy of automatic classification, it is necessary to increase the number of X-ray emitting stars, since the majority of X-ray emitting sources are quasars and galaxies. The results obtained here will be used for the optical spectral survey performed by the Large sky Area Multi-Object fiber Spectroscopic Telescope (LAMOST, also named the Guo Shou Jing Telescope), which is a Chinese national scientific research facility operated by the National Astronomical Observatories, Chinese Academy of Sciences.

  4. Dr. David Sawyer, Mickey Mouse and Dr. David Brown attend a ceremony at Ronald McNair Middle School

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. David Sawyer (left), Superintendent of the Brevard County School District, Mickey Mouse, and Dr. David Brown, a NASA astronaut, attend a tribute to NASA astronaut Ronald McNair held in the gymnasium of Ronald McNair Magnet School in Cocoa, Fla. During the tribute, Walt Disney World presented a portrait of McNair to the school, which had previously been renamed for the fallen astronaut. McNair was one of a crew of seven who lost their lives during an accident following launch of the Space Shuttle Challenger in January 1986.

  5. Group Achievement Award: The SCUBA team; George Darwin Lecturer: Dr Neil Gehrels; Harold Jeffreys Lecturer: Dr Emma Bunce; Honorary Fellow

    NASA Astrophysics Data System (ADS)

    2009-02-01

    The Group Achievement Award goes to the SCUBA team of W K Gear, W S Holland, E I Robson, C R Cunningham, J F Lightfoot, T Jenness, R J Ivison, J A Stevens, P A R Ade, M J Griffin, W D Duncan, J A Murphy and D A Naylor. The 2009 George Darwin Lecturer is Dr Neil Gehrels, Chief of the Astroparticle Physics Laboratory at the NASA Goddard Space Flight Center. The 2009 Harold Jeffreys Lecturer is Dr Emma Bunce of the University of Leicester.

  6. Dr. Chad E. Finn, 2013 Wilder Medal Recipient

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Dr. Chad Finn took over the leadership of the USDA-ARS small fruit breeding program in Corvallis, Oregon in 1993 after three years working as an extension horticulturist in the Department of Horticulture at the University of Missouri, Columbia. Since taking over this program he has developed what is...

  7. A Dr. Martin Luther King, Jr. Curriculum: Playing the Dream.

    ERIC Educational Resources Information Center

    Clemens, Sydney Gurewitz

    1988-01-01

    Discusses curriculum for young children centered around the beliefs and teachings of Dr. Martin Luther King, Jr. His works are interpreted in a human rights context in which children find their voice in the peaceable resolution of everyday conflicts. Describes the Child of the Day program. (Author/RWB)

  8. The life and legacy of Dr. Lee Baldwin

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This paper outlines the life and legacy of the late Dr. Ransom L. Baldwin, V. The purpose was to highlight the impact his teaching and research had on the international energy and protein metabolism communities at their fourth international conference. The paper will be presented at the outset of ...

  9. Another Use for Dr. Seuss: Reading for Social Skills

    ERIC Educational Resources Information Center

    Wolf, Janice J.; Baker, Pamela Hudson

    2012-01-01

    Time is limited. Teachers often struggle to address the diverse needs of learners in their classrooms, especially when faced with academic and social skills concerns. Finding effective ways to teach social skills in the context of academic instruction makes sense. Books by Dr. Seuss provide a variety of high-interest stories that can be used to…

  10. Bullying Among Teenage Girls: An Interview with Dr. Harriet Mosatche

    ERIC Educational Resources Information Center

    Prevention Researcher, 2004

    2004-01-01

    Dr. Harriet Mosatche is an advice columnist on a web site for teen girls, as well as the Senior Director of Research and Programs at the Girl Scouts of the USA. Because of these dual roles, she has a unique perspective on the bullying issue. In this interview she answers a number of questions about bullying among teenage girls, including how boys…

  11. 28. View of data test area for DR data take ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. View of data test area for DR data take off set operators panel and cabinet at second floor of transmitter building no. 102 in MIP area. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  12. Focus on Fitness: Q&A with Dr. Greene

    ERIC Educational Resources Information Center

    Greene, Alan

    2005-01-01

    Dr. Greene answers the following question in this brief article focusing on fitness: Everyone knows that children need plenty of exercise to stay healthy--But what does "fitness" really involve for young children? Following this discussion, the topics presented include: snack of the month; nutrition fact; and activities, "Move to the Music" and…

  13. Dr. Wernher Von Braun with Congressman Gerald R. fod

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On a visit to the Marshall Space Flight Center in April, 1964, Congressman Gerald R. Ford, Jr. Republican of Michigan, was warmly greeted by Dr. Wernher Von Braun, Marshall Space Flight Center director. Ford, along with two other congressmen, visited the center for a briefing on the Saturn program and for a tour of the facilities.

  14. Dr. Seuss's Sound Words: Playing with Phonics and Spelling.

    ERIC Educational Resources Information Center

    Gardner, Traci

    Boom! Br-r-ring! Cluck! Moo!--exciting sounds are everywhere. Whether visiting online sites that play sounds or taking a "sound hike," ask your students to notice the sounds they hear, then write their own book, using sound words, based on Dr. Seuss's "Mr. Brown Can MOO! Can You?" During the three 45-minute sessions, grade K-2 students will:…

  15. Trial by Newspaper: The Strange Case of Dr. Karl Muck.

    ERIC Educational Resources Information Center

    Kagan, Sheldon S.

    1993-01-01

    Examines the case of Dr. Karl Muck, conductor of the Boston Symphony Orchestra who was accused of espionage in 1917. Suggests that the espionage charge was a fiction created by newspapers, beginning with "The Providence Journal." Concludes that Muck admitted to being a spy rather than reveal the name of the woman with whom he had an extramarital…

  16. Dr Skateboard's Action Science: Teaching Physics in Context

    ERIC Educational Resources Information Center

    Robertson, William H.

    2009-01-01

    In order to create student interest and promote new connections to the understanding of fundamental physics concepts, there is a need for new approaches and methods that are both contemporary and relevant. Dr Skateboard's Action Science, a curriculum supplement comprising video instruction and classroom activities, is an example that focuses on…

  17. Dr. Edward de Bono's Six Thinking Hats and Numeracy

    ERIC Educational Resources Information Center

    Paterson, Anne

    2006-01-01

    In education, the term "metacognition" describes thinking about thinking. Within mathematics, the term "metacomputation" describes thinking about computational methods and tools. This article shows how Dr. Edward de Bono's Six Thinking Hats can be used to demonstrate metacognition and metacomputation in the primary classroom. The article suggests…

  18. 7. View of DR 3 antenna typical front stay concrete ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. View of DR 3 antenna typical front stay concrete showing embedment anchors, foundation steel base plate, vertical member with small diameter turnbuckles, antenna assembly in background, and story board for scale. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  19. 3. View of middle DR 2 antenna looking north 30 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. View of middle DR 2 antenna looking north 30 degrees west and showing radar scanner building no. 105 east face through antenna. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  20. 2. View of southerly DR 1 antenna looking north 25 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. View of southerly DR 1 antenna looking north 25 degrees west and and showing radar scanner building no. 105 east face through antenna. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  1. 39. View of checkout indicator computer console for DR beams, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    39. View of checkout indicator computer console for DR beams, TR chains, and special checkout target control located in CSMR in transmitter building no. 102. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  2. Dr. von Braun, Mayor Searcy, and General Medaris

    NASA Technical Reports Server (NTRS)

    1959-01-01

    Dr. Wernher von Braun, Director of the U.S. Army Ballistic Missile Agency's (ABMA) Development Operations Division, talks to Huntsville Mayor R. B. 'Speck' Searcy, center, and Army Ordnance Missile Command (ARMC) Major General John B. Medaris, right, during 'Moon Day' celebrations in downtown Huntsville, Alabama. (Courtesy of Huntsville/Madison County Public Library)

  3. Oxygen and Metastasis: A Conversation with Dr. Nick Restifo

    Cancer.gov

    Dr. Nick Restifo, a senior investigator in NCI’s Center for Cancer Research, discusses his recently published study finding that Oxygen, a molecule necessary for life, paradoxically aids cancer metastasis to the lung by impairing cancer-killing immune cells.

  4. Hospitals for sale.

    PubMed

    Costello, Michael M; West, Daniel J; Ramirez, Bernardo

    2011-01-01

    The pace of hospital merger and acquisition activity reflects the economic theory of supply and demand: Publicly traded hospital companies, private equity funds, and large nonprofit hospital systems are investing capital to purchase and operate freestanding community hospitals at a time when many of those hospitals find themselves short of capital reserves and certain forms of management expertise. But the sale of those community hospitals also raises questions about the impact of absentee ownership on the communities which those hospitals serve. PMID:21864058

  5. Dynamic Star Formation in the Massive DR21 Filament

    SciTech Connect

    Schneider, N.; Csengeri, T.; Bontemps, S.; Motte, F.; Simon, R.; Hennebelle, P.; Federrath, C.; Klessen, R.; /ZAH, Heidelberg /KIPAC, Menlo Park

    2010-08-25

    The formation of massive stars is a highly complex process in which it is unclear whether the star-forming gas is in global gravitational collapse or an equilibrium state supported by turbulence and/or magnetic fields. By studying one of the most massive and dense star-forming regions in the Galaxy at a distance of less than 3 kpc, i.e. the filament containing the well-known sources DR21 and DR21(OH), we attempt to obtain observational evidence to help us to discriminate between these two views. We use molecular line data from our {sup 13}CO 1 {yields} 0, CS 2 {yields} 1, and N{sub 2}H{sup +} 1 {yields} 0 survey of the Cygnus X region obtained with the FCRAO and CO, CS, HCO{sup +}, N{sub 2}H{sup +}, and H{sub 2}CO data obtained with the IRAM 30m telescope. We observe a complex velocity field and velocity dispersion in the DR21 filament in which regions of the highest column-density, i.e., dense cores, have a lower velocity dispersion than the surrounding gas and velocity gradients that are not (only) due to rotation. Infall signatures in optically thick line profiles of HCO{sup +} and {sup 12}CO are observed along and across the whole DR21 filament. By modelling the observed spectra, we obtain a typical infall speed of {approx}0.6 km s{sup -1} and mass accretion rates of the order of a few 10{sup -3} M{sub {circle_dot}} yr{sup -1} for the two main clumps constituting the filament. These massive clumps (4900 and 3300 M{sub {circle_dot}} at densities of around 10{sup 5} cm{sup -3} within 1 pc diameter) are both gravitationally contracting. The more massive of the clumps, DR21(OH), is connected to a sub-filament, apparently 'falling' onto the clump. This filament runs parallel to the magnetic field. Conclusions. All observed kinematic features in the DR21 filament (velocity field, velocity dispersion, and infall), its filamentary morphology, and the existence of (a) sub-filament(s) can be explained if the DR21 filament was formed by the convergence of flows on large

  6. Functional polymorphism of each of the two HLA-DR beta chain loci demonstrated with antigen-specific DR3- and DRw52-restricted T cell clones

    PubMed Central

    1988-01-01

    HLA-DR3- and HLA-DRw52-associated functional polymorphism was investigated with selected tetanus toxoid (TT)-specific T cell clones. We have shown earlier that HLA-DR antigens are encoded by two distinct loci, DR beta I and DR beta III. The alloantigenic determinant(s) defined by the serological HLA-DR3 specificity map to the former, while the supratypic HLA-DRw52 determinants map to DR beta III. Furthermore, we have recently recognized by DNA sequencing three alleles of HLA- DRw52 at locus DR beta III, referred to as 52 a, b, and c. Our objective was to correlate the pattern of T cell restriction with the gene products of individual DR beta chain loci and with the three newly described alleles of locus DR beta III. Among the selected T cell clones, 5 reacted exclusively when TT was presented by HLA-DR3+ APCs (TT-DR3-APC). In contrast, two T cell clones were stimulated by TT- DRw52-APC. More specifically, these two T cell clones (Clones 10 and 16) were stimulated by different subsets of TT-DRw52-APC. Clone 16 responded to some DR3 and TT-DRw6-APC, while clone 10 was stimulated by other TT-DR3 and TT-DRw6, and all TT-DR5-APC. This same pattern of DRw52 restriction was found in panel, as well as in family studies. Because this suggested a correlation with the pattern of DRw52 polymorphism observed earlier by DNA sequencing and oligonucleotide hybridization, the APC used in these experiments were typed for the 52 a, b, and c alleles of locus DR beta III by allele-specific oligonucleotide probes. This distribution overlapped exactly with the stimulation pattern defined by the T cell clones. Clone 16 responded to TT-52a-APC, clone 10 to TT-52b-APC, and both clones to a TT-52c-APC. The response of the T cell clones was inhibited differentially by mAbs to DR. Raising TT concentration, or increasing HLA-class II expression with INF-gamma both affected the magnitude of response of the TT- specific clones but did not modify their specificities. These results demonstrate that

  7. 78 FR 29781 - Before Administrative Judges: Ronald M. Spritzer, Chairman, Dr. Anthony J. Baratta, Dr. Randall J...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... COMMISSION Atomic Safety and Licensing Board Before Administrative Judges: Ronald M. Spritzer, Chairman, Dr... and Written Limited Appearance Statements) May 15, 2013. Pursuant to 10 CFR 2.312, the Atomic Safety... submitted to: Mail: Administrative Judge Ronald M. Spritzer, Atomic Safety and Licensing Board Panel,...

  8. Type 1 diabetes risk for human leukocyte antigen (HLA)-DR3 haplotypes depends on genotypic context: association of DPB1 and HLA class I loci among DR3- and DR4-matched Italian patients and controls.

    PubMed

    Noble, Janelle A; Martin, Adelle; Valdes, Ana M; Lane, Julie A; Galgani, Andrea; Petrone, Antonio; Lorini, Renata; Pozzilli, Paolo; Buzzetti, Raffaella; Erlich, Henry A

    2008-01-01

    Patients with high-risk human leukocyte antigen (HLA)-DR-DQ genotypes for type 1 diabetes (T1D) were compared with HLA-matched controls to evaluate T1D risk for other HLA loci, including HLA-A, -B, -Cw, and DPB1. Patients (n = 133) with high-risk genotypes (DR3/DR3, DR3/DR4, DR4/DR4) were selected from the Lazio (Rome) region of Italy. Screening of more than 9000 patients from the Lazio region and northern Italy yielded 162 controls with high-T1D-risk haplotypes. Although the overall distributions did not differ significantly, allele frequency differences were discovered between the controls from Lazio and controls from northern Italy for some alleles previously determined to affect T1D risk, such as A*3002, DPB1*0301, and DPB1*0402. Therefore, Lazio patient data were compared both with the Lazio subset of controls (n = 53) and with the entire group of controls for association analyses. Significant allele frequency differences between patients and DR-DQ-matched controls existed for specific alleles at all loci. Data for the DR3/DR3 subset of patients and controls demonstrated an increase of Cw*0702 in patients. Compared with controls, reduced patient frequencies were seen for several alleles, including A*0101, B*0801, and Cw*0701, all on the highly conserved, extended DR3 haplotype known as 8.1 in DR3/DR3, but not DR3/DR4, subgroup. DPB1*0101, often reported on 8.1 haplotypes, was also less frequent in DR3/DR3 patients than controls. Analysis of family-based data from the HBDI repository was consistent with the observed results from the Italian patients, indicating the presence of a T1D-protective locus at or near A*0101 and a second T1D-protective locus at or near DPB1*0101. These data indicate that T1D risk conferred by the 8.1 haplotype is genotype dependent. PMID:18486765

  9. Sampling From the Proteome to the Human Leukocyte Antigen-DR (HLA-DR) Ligandome Proceeds Via High Specificity*

    PubMed Central

    Mommen, Geert P. M.; Marino, Fabio; Meiring, Hugo D.; Poelen, Martien C. M.; van Gaans-van den Brink, Jacqueline A. M.; Mohammed, Shabaz; Heck, Albert J. R.; van Els, Cécile A. C. M.

    2016-01-01

    Comprehensive analysis of the complex nature of the Human Leukocyte Antigen (HLA) class II ligandome is of utmost importance to understand the basis for CD4+ T cell mediated immunity and tolerance. Here, we implemented important improvements in the analysis of the repertoire of HLA-DR-presented peptides, using hybrid mass spectrometry-based peptide fragmentation techniques on a ligandome sample isolated from matured human monocyte-derived dendritic cells (DC). The reported data set constitutes nearly 14 thousand unique high-confident peptides, i.e. the largest single inventory of human DC derived HLA-DR ligands to date. From a technical viewpoint the most prominent finding is that no single peptide fragmentation technique could elucidate the majority of HLA-DR ligands, because of the wide range of physical chemical properties displayed by the HLA-DR ligandome. Our in-depth profiling allowed us to reveal a strikingly poor correlation between the source proteins identified in the HLA class II ligandome and the DC cellular proteome. Important selective sieving from the sampled proteome to the ligandome was evidenced by specificity in the sequences of the core regions both at their N- and C- termini, hence not only reflecting binding motifs but also dominant protease activity associated to the endolysosomal compartments. Moreover, we demonstrate that the HLA-DR ligandome reflects a surface representation of cell-compartments specific for biological events linked to the maturation of monocytes into antigen presenting cells. Our results present new perspectives into the complex nature of the HLA class II system and will aid future immunological studies in characterizing the full breadth of potential CD4+ T cell epitopes relevant in health and disease. PMID:26764012

  10. Strong association between microsatellites and an HLA-B, DR haplotype (B18-DR3): Implication for microsatellite evolution

    SciTech Connect

    Crouau-Roy, B.; Bouzekri, N.; Clayton, J.

    1996-09-01

    The HLA haplotype B18-DR3 has a widespread geographical distribution, but has its greatest frequencies in Southern Europe, probably vestigial of the earliest populations of this region, particularly in the Pays Basque and Sardinia. This haplotype is of medical significance, being that most implicated as a factor of risk in insulin-dependent diabetes mellitus. In this study, the closely linked microsatellite markers (TNFa,b,c) in the region of the tumor necrosis factor (TNF) genes have been used in an attempt to subtype this haplotype in the two populations and/or in healthy and diabetic populations. A total of 79 HLA-B18-DR3 haplotypes were analyzed: 54 in Basques (12 from healthy individuals and 42 from diabetics or their first-degree relatives) and 25 in Sardinians (13 from healthy and 13 from diabetic individuals). The TNF haplotype a1-b5-c2 is completely associated with B18-DR3 in both populations. The homogeneity of the B18-DR3 haplotype in two ethnically pure populations implies stability in evolution, which suggest that the mutation rate of these microsatellite markers must be less than is usually assumed (i.e., {approximately} 5x10{sup {minus}6} per site per generation). Such markers should be powerful tools for studying genetic drift and admixture of populations, but it remains to be established whether this stability is a rule for all microsatellites in HLA haplotypes or whether or whether it is restricted to some microsatellites and/or some HLA haplotypes. The population genetics of those microsatellites associated with HLA B18-DR3 was also studied in a random sample of the Basque population. 44 refs., 3 tabs.

  11. Influence of Patient and Hospital Characteristics on the Performance of Direct Reconstruction after Mastectomy

    PubMed Central

    Hartrampf, J.; Ansmann, L.; Wesselmann, S.; Beckmann, M. W.; Pfaff, H.; Kowalski, C.

    2014-01-01

    Aim: International studies have shown that the performance of a direct (or immediate) reconstruction (DR) after mastectomy is associated with patient (e.g., socio-economic status, insurance status, age) and hospital (number of cases, teaching status) characteristics. The present article addresses the question if such relationships also exist in Germany. Material and Methods: The results of a nationwide questionnaire to the patients of certified breast cancer centres were coupled with the clinical features of the patients and the characteristics of the hospital. Predictors for receiving a DR (vs. delayed or no reconstruction) were estimated by means of a logistic multilevel model for a sample of 1165 patients from 105 certified locations. Results: Substantial differences between the treating hospitals were found (intraclass correlation coefficient null model: 0.195) which can in part be explained by the total model (total model: 0.169). Patients with the following features are more likely to receive a DR: younger age, private health insurance, secondary school leaving certificate (vs. primary school leaving certificate), lower stage and acquisition of more information about reconstruction. ASA and partnership status are not statistically significantly related with DR. DR is more likely to be performed in hospitals with higher caseload of patients with primary breast cancer. Teaching status, operations per surgeon and urbanity of the location are not related to receiving a DR. Conclusions: Non-clinical features of the patients and the primary case number are associated with the performance of a DR, this poses questions concerning reasons and the equality of health care. PMID:25568467

  12. Billing delays cause hassles, but hospitals still have to pay for services provided.

    PubMed

    Decker, R

    1988-06-01

    A hospital has a contract with the manufacturer to maintain and service copying machines owned by the hospital. The contract calls for the hospital to pay a set minimum monthly fee plus a per-copy charge for all copies made over a set amount. The supplier doesn't furnish any paper products. Recently the hospital received an invoice for 17 months' service. When contacted about this large bill, the supplier told the hospital that it had inadvertently dropped the hospital from its billing computer and had failed to bill the hospital each month. The hospital protested the pressure that this billing practice put upon its budget and asked for an adjustment. The supplier refused to make any adjustment in the amount but did agree to accept the arrears in monthly payments over a year with no interest charges. In this dialogue below, Dr. Decker discusses the legal issues involved in this situation. PMID:10287890

  13. Can hospitals compete on quality? Hospital competition.

    PubMed

    Sadat, Somayeh; Abouee-Mehrizi, Hossein; Carter, Michael W

    2015-09-01

    In this paper, we consider two hospitals with different perceived quality of care competing to capture a fraction of the total market demand. Patients select the hospital that provides the highest utility, which is a function of price and the patient's perceived quality of life during their life expectancy. We consider a market with a single class of patients and show that depending on the market demand and perceived quality of care of the hospitals, patients may enjoy a positive utility. Moreover, hospitals share the market demand based on their perceived quality of care and capacity. We also show that in a monopoly market (a market with a single hospital) the optimal demand captured by the hospital is independent of the perceived quality of care. We investigate the effects of different parameters including the market demand, hospitals' capacities, and perceived quality of care on the fraction of the demand that each hospital captures using some numerical examples. PMID:25711185

  14. Hospital-acquired pneumonia

    MedlinePlus

    ... tends to be more serious than other lung infections because: People in the hospital are often very sick and cannot fight off ... prevent pneumonia. Most hospitals have programs to prevent hospital-acquired infections.

  15. Star Formation in the DR21 Region (B)

    NASA Technical Reports Server (NTRS)

    2004-01-01

    [figure removed for brevity, see original site] Annotated mosaic

    Hidden behind a shroud of dust in the constellation Cygnus is an exceptionally bright source of radio emission called DR21. Visible light images reveal no trace of what is happening in this region because of heavy dust obscuration. In fact, visible light is attenuated in DR21 by a factor of more than 10,000,000,000,000,000,000,000,000,000,000,000,000,000 (ten thousand trillion heptillion).

    New images from NASA's Spitzer Space Telescope allow us to peek behind the cosmic veil and pinpoint one of the most massive natal stars yet seen in our Milky Way galaxy. The never-before-seen star is 100,000 times as bright as the Sun. Also revealed for the first time is a powerful outflow of hot gas emanating from this star and bursting through a giant molecular cloud.

    The upper image is a large-scale mosaic assembled from individual photographs obtained with the InfraRed Array Camera (IRAC) aboard Spitzer. The image covers an area about two times that of a full moon. The mosaic is a composite of images obtained at mid-infrared wavelengths of 3.6 microns (blue), 4.5 microns (green), 5.8 microns (orange) and 8 microns (red). The brightest infrared cloud near the top center corresponds to DR21, which presumably contains a cluster of newly forming stars at a distance of 10,000 light-years.

    Protruding out from DR21 toward the bottom left of the image is a gaseous outflow (green), containing both carbon monoxide and molecular hydrogen. Data from the Spitzer spectrograph, which breaks light into its constituent individual wavelengths, indicate the presence of hot steam formed as the outflow heats the surrounding molecular gas. Outflows are physical signatures of processes that create supersonic beams, or jets, of gas. They are usually accompanied by discs of material around the new star, which likely contain the materials from which future planetary systems are formed. Additional newborn stars

  16. Gestosis and fetal rejection: immunopathogenetic role of HLA-DR.

    PubMed

    De Luca Brunori, I; Battini, L; Mariotti, M L; Pecori, F; Urbano, M; Filippeschi, M; Scida, P; Simonelli, M

    1994-01-01

    In this study we faced the problem of etiopathogenesis of EPH Gestosis, focusing our attention on the role of immunitary aspects in determining its onset. We typed HLA-DR in 20 couples with gestosic patient and in 20 control couples. Blood samples were taken into heparin-treated test tubes, from all the couples and HLA typed through standard lymphotoxicity technique in accordance with Terasaky (1). Our results in couples with a gestosic patient, showed homozygosis in 65% of patients and in 70% of partners; in 35% of cases homozygosis was present in both partners, and these were the most severe cases. It is also worth mentioning that in all the couples with gestosic patient, at least one of the partners resulted homozygotic. Homozygosis would therefore represent a predisposing factor in the etiopathogenesis of gestosis, and pre-conception HLA-DR typing of the couple could prove to be a valid alarm signal for gestosis risk. PMID:7994872

  17. 21. Dr. Harrison E. Stroud poses in front of his ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Dr. Harrison E. Stroud poses in front of his newly completed building at the northeast corner of Central Avenue and the alley north of Washington Street in about 1900 or 1901. In 1901, the building seen here was enlarged by the construction of an addition of similar design immediately to the north (left). Virtually the entire west elevation of the initial building is depicted in this view. Credit ADLAPR. - Stroud Building, 31-33 North Central Avenue, Phoenix, Maricopa County, AZ

  18. VEHICLE ASSEMBLY BUILDING [VAB] & TOPPING OFF CEREMONIES SPEAKER DR. DEBUS

    NASA Technical Reports Server (NTRS)

    1965-01-01

    Dr. Kurt H. Debus, KSC's first director, was a major speaker at the ceremonies ''topping off'' the Vehicle Assembly Building on April 14, 1965. A crawler-transporter is at the right. At the time of its completion, the 129 million cubic foot structure was the largest building in the world. Originally designed and built to accommodate the Saturn V/Apollo used in Project Apollo, the VAB was later modified for its role in the Space Shuttle program.

  19. 105-DR Large Sodium Fire Facility closure plan. Revision 1

    SciTech Connect

    Not Available

    1993-05-01

    The Hanford Site, located northwest of the city of Richland, Washington, houses reactors, chemical-separation systems, and related facilities used for the production of special nuclear materials, and activities associated with nuclear energy development. The 105-DR Large Sodium Fire Facility (LSFF), which was in operation from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility. The LSFF was established to provide a means of investigating fire and safety aspects associated with large sodium or other metal alkali fires in the liquid metal fast breeder reactor (LMFBR) facilities. The 105-DR Reactor facility was designed and built in the 1950`s and is located in the 100-D Area of the Hanford Site. The building housed the 105-DR defense reactor, which was shut down in 1964. The LSFF was initially used only for engineering-scale alkali metal reaction studies. In addition, the Fusion Safety Support Studies program sponsored intermediate-size safety reaction tests in the LSFF with lithium and lithium lead compounds. The facility has also been used to store and treat alkali metal waste, therefore the LSFF is subject to the regulatory requirements for the storage and treatment of dangerous waste. Closure will be conducted pursuant to the requirements of the Washington Administrative Code (WAC) 173-303-610. This closure plan presents a description of the facility, the history of waste managed, and the procedures that will be followed to close the LSFF as an Alkali Metal Treatment Facility. No future use of the LSFF is expected.

  20. Dr. John Stack and other NASA Langley Research Center Visitors

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Front Row, left to right: Mrs. Elsa Hoare and Major Philip L. Teed - staff members, Vickers-Armstrongs, Ltd., Weybridge, England: Dr. Barnes Wallis - Chief of Aeronautical Research, Vicers-Armstrong, Ltd., Weybridge, England. Back Row, left to right: Norman W. Boorer and Cecil W. Hayes - Staff members, Vickers-Armstrongs, Ltd., Weybridge, England; John R. Christie - Ministry of Supply, London, England; Philip A. Hufton - Chief Supt., Royal Aircraft Establishment, Bedford, England; Lindsey I. Turner, Jr. - Langley Research Center. Photographed November 13, 1958.

  1. ORAC-DR: A generic data reduction pipeline infrastructure

    NASA Astrophysics Data System (ADS)

    Jenness, Tim; Economou, Frossie

    2015-03-01

    ORAC-DR is a general purpose data reduction pipeline system designed to be instrument and observatory agnostic. The pipeline works with instruments as varied as infrared integral field units, imaging arrays and spectrographs, and sub-millimeter heterodyne arrays and continuum cameras. This paper describes the architecture of the pipeline system and the implementation of the core infrastructure. We finish by discussing the lessons learned since the initial deployment of the pipeline system in the late 1990s.

  2. Of brain and bone: the unusual case of Dr. A.

    PubMed

    Narvid, J; Gorno-Tempini, M L; Slavotinek, A; Dearmond, S J; Cha, Y H; Miller, B L; Rankin, K

    2009-06-01

    Frontotemporal dementia (FTD) is a clinical syndrome characterized by progressive decline in social conduct and a focal pattern of frontal and temporal lobe damage. Its biological basis is still poorly understood but the focality of the brain degeneration provides a powerful model to study the cognitive and anatomical basis of social cognition. Here, we present Dr. A, a patient with a rare hereditary bone disease (hereditary multiple exostoses) and FTD (pathologically characterized as Pick's disease), who presented with a profound behavioral disturbance characterized by acquired sociopathy. We conducted a detailed genetic, pathological, neuroimaging and cognitive study, including a battery of tests designed to investigate Dr. A's abilities to understand emotional cues and to infer mental states and intentions to others (theory of mind). Dr. A's genetic profile suggests the possibility that a mutation causing hereditary multiple exostoses, Ext2, may play a role in the pattern of neurodegeneration in frontotemporal dementia since knockout mice deficient in the Ext gene family member, Ext1, show severe CNS defects including loss of olfactory bulbs and abnormally small cerebral cortex. Dr. A showed significant impairment in emotion comprehension, second order theory of mind, attribution of intentions, and empathy despite preserved general cognitive abilities. Voxel-based morphometry on structural MRI images showed significant atrophy in the medial and right orbital frontal and anterior temporal regions with sparing of dorsolateral frontal cortex. This case demonstrates that social and emotional dysfunction in FTD can be dissociated from preserved performance on classic executive functioning tasks. The specific pattern of anatomical damage shown by VBM emphasizes the importance of the network including the superior medial frontal gyrus as well as temporal polar areas, in regulation of social cognition and theory of mind. This case provides new evidence regarding the

  3. Of Brain and Bone: The Unusual Case of Dr. A

    PubMed Central

    Narvid, J; Gorno-Tempini, ML; Slavotinek, A; DeArmond, SJ; Cha, YH; Miller, BL; Rankin, K.P

    2009-01-01

    Frontotemporal dementia (FTD) is a clinical syndrome characterized by progressive decline in social conduct and a focal pattern of frontal and temporal lobe damage. Its biological basis is still poorly understood but the focality of the brain degeneration provides a powerful model to study the cognitive and anatomical basis of social cognition. Here, we present Dr. A, a patient with a rare hereditary bone disease (hereditary multiple exostoses) and FTD (pathologically characterized as Pick’s disease), who presented with a profound behavioral disturbance characterized by acquired sociopathy. We conducted a detailed genetic, pathological, neuroimaging and cognitive study, including a battery of tests designed to investigate Dr. A’s abilities to understand emotional cues and to infer mental states and intentions to others (theory of mind). Dr. A’s genetic profile suggests the possibility that a mutation causing hereditary multiple exostoses, Ext2, may play a role in the pattern of neurodegeneration in frontotemporal dementia since knockout mice deficient in the Ext gene family member, Ext1, show severe CNS defects including loss of olfactory bulbs and abnormally small cerebral cortex. Dr. A showed significant impairment in emotion comprehension, second order theory of mind, attribution of intentions, and empathy despite preserved general cognitive abilities. Voxel-based morphometry on structural MRI images showed significant atrophy in the medial and right orbital frontal and anterior temporal regions with sparing of dorsolateral frontal cortex. This case demonstrates that social and emotional dysfunction in FTD can dissociate from preserved performance on classic executive functioning tasks. The specific pattern of anatomical damage shown by VBM emphasizes the importance of the network including the superior medial frontal gyrus as well as temporal polar areas, in regulation of social cognition and theory of mind. This case provides new evidence regarding the

  4. 8. View of DR 3 antenna showing lower front connector, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. View of DR 3 antenna showing lower front connector, third from left vertical member at first level above foundation level, showing small diameter turnbuckle stays, vertical member with flange connection, and various struts and connectors with antenna assembly in background. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  5. 4. View of northerly DR 3 antenna looking north 35 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. View of northerly DR 3 antenna looking north 35 degrees west and showing radar scanner building no. 106 east face through antenna and partial view of satcom communication dome (attached to radar transmitter building 102) in left side of photograph. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  6. Dr. von Braun in the Gemini Simulator at MSC

    NASA Technical Reports Server (NTRS)

    1964-01-01

    In this 1964 photograph, Marshall Space Flight Center (MSFC) Director Dr. Wernher von Braun (in commander's seat, background) tries out the Gemini Simulator at the Marned Spacecraft Center (now Johnson Space Center). Looking on from the pilot's seat is J.P. Kuettner, deputy director of MSFC Saturn Apollo Systems Office, and standing at left, Warren J. North, chief of Manned Spacecraft Center's (MSC) Flight Crew Support Division.

  7. 75 FR 68603 - Proposed Information Collection; Comment Request; Office of Education Dr. Nancy Foster...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    ... Education Dr. Nancy Foster Scholarship Program AGENCY: National Oceanic and Atmospheric Administration... successful scholarship candidates, generating internal NOAA reports and articles to demonstrate the success of its program. The Dr. Nancy Foster Scholarship Program is available to graduate students...

  8. For Dr. Nancy Snyderman's Parents, Staying Close to Family Is Key

    MedlinePlus

    ... As Chief Medical Editor for NBC News and host of the popular MSNBC show, Dr. Nancy , Dr. ... to overuse either. Communication is important in any relationship, and with family, it's vital. I am so ...

  9. Dr. Wernher Von Braun leads a tour of the S-IC checkout area.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Eberhard Rees, Charles Schultze, James Webb, Elmer Staats, Comptroller General of the United States, and Dr. Wernher Von Braun tour the S-IC checkout area in the Marshall Space Flight Center quality lab.

  10. Dr. Lindberg's Legacy : Charting A New Course | NIH MedlinePlus the Magazine

    MedlinePlus

    ... more. Don also created the National Center for Biotechnology Information (NCBI). NCBI has been a focal point ... with Dr. Lindberg (right) and National Center for Biotechnology Information Director Dr. David Lipman (center) at a ...

  11. Dr. Lytle Adams' incendiary "bat bomb" of World War II.

    PubMed

    Christen, Arden G; Christen, Joan A

    2004-11-01

    On December 7, 1941, a 60-year old dentist from Irwin, Pennsylvania, Dr. Lytle S. Adams, was driving home from a vacation at Carlsbad Caverns in New Mexico. Hours earlier, he had been gripped with amazement as he witnessed millions of bats exiting the caves of Carlsbad. Listening to his car radio on his return trip, he was shocked to hear that Japan had just attacked Pearl Harbor. Dr. Adams, outraged over this travesty, began to mentally construct a plan for U.S. retaliation. As his thoughts returned to the countless bats that had awed him, he formed a tentative plan: millions of these small, flying mammals could be connected to tiny, time-fused incendiary bombs, and then released to land on the flimsily constructed structures which dotted the cities of Japan. Within a few minutes, the bombs would explode and enflame the entire urban areas. He postulated that these immeasurable numbers of fires, spreading their devastation over such vast areas within Japanese cities would result in the enemy's speedy surrender. This article documents the futile efforts of Dr. Adams, his team and the U.S. government to develop and employ an effective, incendiary bat bomb. The recently developed atom bomb, a far more deadly weapon was used in its place. PMID:15666497

  12. Dr.LiTHO: a development and research lithography simulator

    NASA Astrophysics Data System (ADS)

    Fühner, Tim; Schnattinger, Thomas; Ardelean, Gheorghe; Erdmann, Andreas

    2007-03-01

    This paper introduces Dr.LiTHO, a research and development oriented lithography simulation environment developed at Fraunhofer IISB to flexibly integrate our simulation models into one coherent platform. We propose a light-weight approach to a lithography simulation environment: The use of a scripting (batch) language as an integration platform. Out of the great variety of different scripting languages, Python proved superior in many ways: It exhibits a good-natured learning-curve, it is efficient, available on virtually any platform, and provides sophisticated integration mechanisms for existing programs. In this paper, we will describe the steps, required to provide Python bindings for existing programs and to finally generate an integrated simulation environment. In addition, we will give a short introduction into selected software design demands associated with the development of such a framework. We will especially focus on testing and (both technical and user-oriented) documentation issues. Dr.LiTHO Python files contain not only all simulation parameter settings but also the simulation flow, providing maximum flexibility. In addition to relatively simple batch jobs, repetitive tasks can be pooled in libraries. And as Python is a full-blown programming language, users can add virtually any functionality, which is especially useful in the scope of simulation studies or optimization tasks, that often require masses of evaluations. Furthermore, we will give a short overview of the numerous existing Python packages. Several examples demonstrate the feasibility and productiveness of integrating Python packages into custom Dr.LiTHO scripts.

  13. RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis.

    PubMed

    Brünker, Peter; Wartha, Katharina; Friess, Thomas; Grau-Richards, Sandra; Waldhauer, Inja; Koller, Claudia Ferrara; Weiser, Barbara; Majety, Meher; Runza, Valeria; Niu, Huifeng; Packman, Kathryn; Feng, Ningping; Daouti, Sherif; Hosse, Ralf J; Mössner, Ekkehard; Weber, Thomas G; Herting, Frank; Scheuer, Werner; Sade, Hadassah; Shao, Cuiying; Liu, Bin; Wang, Peng; Xu, Gary; Vega-Harring, Suzana; Klein, Christian; Bosslet, Klaus; Umaña, Pablo

    2016-05-01

    Dysregulated cellular apoptosis and resistance to cell death are hallmarks of neoplastic initiation and disease progression. Therefore, the development of agents that overcome apoptosis dysregulation in tumor cells is an attractive therapeutic approach. Activation of the extrinsic apoptotic pathway is strongly dependent on death receptor (DR) hyperclustering on the cell surface. However, strategies to activate DR5 or DR4 through agonistic antibodies have had only limited clinical success. To pursue an alternative approach for tumor-targeted induction of apoptosis, we engineered a bispecific antibody (BsAb), which simultaneously targets fibroblast-activation protein (FAP) on cancer-associated fibroblasts in tumor stroma and DR5 on tumor cells. We hypothesized that bivalent binding to both FAP and DR5 leads to avidity-driven hyperclustering of DR5 and subsequently strong induction of apoptosis in tumor cells but not in normal cells. Here, we show that RG7386, an optimized FAP-DR5 BsAb, triggers potent tumor cell apoptosis in vitro and in vivo in preclinical tumor models with FAP-positive stroma. RG7386 antitumor efficacy was strictly FAP dependent, was independent of FcR cross-linking, and was superior to conventional DR5 antibodies. In combination with irinotecan or doxorubicin, FAP-DR5 treatment resulted in substantial tumor regression in patient-derived xenograft models. FAP-DR5 also demonstrated single-agent activity against FAP-expressing malignant cells, due to cross-binding of FAP and DR5 across tumor cells. Taken together, these data demonstrate that RG7386, a novel and potent antitumor agent in both mono- and combination therapies, overcomes limitations of previous DR5 antibodies and represents a promising approach to conquer tumor-associated resistance to apoptosis. Mol Cancer Ther; 15(5); 946-57. ©2016 AACR. PMID:27037412

  14. Identification of death receptors DR4 and DR5 in HTB-12 astrocytoma cell lines and determination of TRAIL sensitivity

    PubMed Central

    Riddick, Elenia; Evans, Shavonda; Rousch, Jeffrey; Gwebu, Ephraim; Banerjee, Hirendra Nath

    2014-01-01

    Astrocytomas are tumors which arise from astrocytes, cells that form the blood-brain barrier. There are very few drugs that successfully treat brain tumors. In this study, the cytotoxic effects on the HTB-12 astrocytoma cell line by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) were studied. The presence of the TRAIL receptors, Death receptor 4 (DR4) and Death receptor 5 (DR5), were detected in HTB-12 cells by Enzyme-Linked Immunosorbent Assay (ELISA). Cytotoxicity assay by Trypan Blue Exclusion Method showed effective cell killing by TRAIL treatment. Thus, the presence of death receptors and TRAIL efficacy raises the therapeutic potential for this type of brain tumor. PMID:25364476

  15. Dr. Wernher Von Braun greeting dignitaries at the Redstone Arsenal airfield.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. George E. Mueller, center, associate administrator for manned space flight, is flanked by Dr. Wernher Von Braun, left, and Dr. Eberhard Rees at the Redstone Arsenal airstrip. the associate adminstrator was making his annual staff visit to the Marshall Space Flight Center.

  16. Enhancing Price Response Programs through Auto-DR: California's 2007 Implementation Experience

    SciTech Connect

    Kiliccote, Sila; Wikler, Greg; Chiu, Albert; Piette, Mary Ann; Kiliccote, Sila; Hennage, Dan; Thomas, Chuck

    2007-12-18

    This paper describes automated demand response (Auto-DR) activities, an innovative effort in California to ensure that DR programs produce effective and sustainable impacts. Through the application of automation and communication technologies coupled with well-designed incentives and DR programs such as Critical Peak Pricing (CPP) and Demand Bidding (DBP), Auto-DR is opening up the opportunity for many different types of buildings to effectively participate in DR programs. We present the results of Auto-DR implementation efforts by the three California investor-owned utilities for the Summer of 2007. The presentation emphasizes Pacific Gas and Electric Company's (PG&E) Auto-DR efforts, which represents the largest in the state. PG&E's goal was to recruit, install, test and operate 15 megawatts of Auto-DR system capability. We describe the unique delivery approaches, including optimizing the utility incentive structures designed to foster an Auto-DR service provider community. We also show how PG&E's Critical Peak Pricing (CPP) and Demand Bidding (DBP) options were called and executed under the automation platform. Finally, we show the results of the Auto-DR systems installed and operational during 2007, which surpassed PG&E's Auto-DR goals. Auto-DR is being implemented by a multi-disciplinary team including the California Investor Owned Utilities (IOUs), energy consultants, energy management control system vendors, the Lawrence Berkeley National Laboratory (LBNL), and the California Energy Commission (CEC).

  17. Hospital Library Administration.

    ERIC Educational Resources Information Center

    Cramer, Anne

    The objectives of a hospital are to improve patient care, while the objectives of a hospital library are to improve services to the staff which will support their efforts. This handbook dealing with hospital administration is designed to aid the librarian in either implementing a hospital library, or improving services in an existing medical…

  18. Measuring Rural Hospital Quality

    ERIC Educational Resources Information Center

    Moscovice, Ira; Wholey, Douglas R.; Klingner, Jill; Knott, Astrid

    2004-01-01

    Increased interest in the measurement of hospital quality has been stimulated by accrediting bodies, purchaser coalitions, government agencies, and other entities. This paper examines quality measurement for hospitals in rural settings. We seek to identify rural hospital quality measures that reflect quality in all hospitals and that are sensitive…

  19. Hospital marketing revisited.

    PubMed

    Costello, M M

    1987-05-01

    With more hospitals embracing the marketing function in their organizational management over the past decade, hospital marketing can no longer be considered a fad. However, a review of hospital marketing efforts as reported in the professional literature indicates that hospitals must pay greater attention to the marketing mix elements of service, price and distribution channels as their programs mature. PMID:10283019

  20. [The fate of the old Jejoong Won following the establishment of the new Jejoong Won (Severance Hospital)].

    PubMed

    Yeo, I S; Park, Y J; Lee, K l; Park, H W

    1998-01-01

    Dr. Allen, the first Protestant missionary in Korea, had an opportunity of saving the life of the queen's nephew shortly after his arrival in Korea in 1884. In gratitude the King established the Royal Korean Hospital (Jejoong Won), the first hospital in Korea, and appointed Dr. Allen in charge of the medical affairs of the hospital. After Dr. Allen's resignation from the mission, the work was successively carried on by Drs. JW Heron, RA Hardie, CC Vinton and OR Avison, the last of whom arrived in 1893. In 1894 the connection of the Hospital with the Korean Government was severed and the work taken over by the Northern Presbyterian Mission. Since then, it has been a distinctly mission institute. In 1900, while attending the Ecumenical Conference of Foreign Missions in Carnegie Hall, New York, Dr. Avison made the acquaintance of a philanthropist LH Severance, who made a gift of $10,000 for a new hospital. This building, the first modern hospital in Korea, was opened and dedicated in 1904. It was named the Severance Hospital. As the new hospital was built, the old hospital building was to be returned to the Korean Government according to the agreement made in 1894. On retaking the old hospital, the Korean Government paid $30,289.99 won for the renovation of the original building and new buildings established in the site during the period of Avison's entire charge of Jejoong Won. The old hospital building was used as an official residence for a diplomatic adviser Stevens, who was assassinated for his pro-Japan activities, and as a social club for Japanese officials. PMID:11624251

  1. GENESI-DR Portal: a scientific gateway to distributed repositories

    NASA Astrophysics Data System (ADS)

    Goncalves, Pedro; Brito, Fabrice; D'Andria, Fabio; Cossu, Roberto; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. "Discovering" which data are available on a "geospatial web" is one of the main challenges ES scientists have to face today. Some well- known data sets are referred to in many places, available from many sources. For core information with a common purpose many copies are distributed, e.g., VMap0, Landsat, and SRTM. Other data sets in low or local demand may only be found in a few places and niche communities. Relevant services, results of analysis, applications and tools are accessible in a very scattered and uncoordinated way, often through individual initiatives from Earth Observation mission operators, scientific institutes dealing with ground measurements, service companies or data catalogues. In the discourse of Spatial Data Infrastructures, there are "catalogue services" - directories containing information on where spatial data and services can be found. For metadata "records" describing spatial data and services, there are "registries". The Geospatial industry coins specifications for search interfaces, where it might do better to reach out to other information retrieval and Internet communities. These considerations are the basis for the GENESI-DR scientific portal, which adopts a simple model allowing the geo-spatial classification and discovery of

  2. [DR. Hanka Weinberg-Heruti: the pediatrician from Merchavia--the first woman-doctor 'Kibbutznik' in the Kibbutz Ha'artzi].

    PubMed

    Shehory-Rubin, Zipora

    2015-07-01

    Dr. Hanka Weinberg-Heruti, a pediatrician at the Ha'Emek Hospital and a member of Kibbutz Merchavia is regarded in the history of medicine in Eretz Israel as the first female physician in the Kibbutz Ha'Artzi movement-Hashomer Hatsa'ir, and one of the founders of children's medicine in the country. Dr. Weinberg-Heruti was able to break the accepted norms of the period and prove "you could be both a hospital doctor and a loyal kibbutz member". This was far from simple for there was an iron rule in that kibbutz movement: "Every member must perform physical labour to build the kibbutz and to work in its framework. This principle is inviolable nor can one deviate from the norm". Dr. Weinberg-Heruti dared to break that rule and prove that a successful combination of both her purposes in life was possible. Thus, the aim of the article is twofold: to survey her unique position as hospital doctor and faithful 'kibbutznik', who dared to break the "holy" principle at the ideological roots of kibbutz life--that it was unthinkable for a member to refrain from physical labour. Secondly, to illuminate her medical career as pediatrician in Ha'Emek Hospital, and describe the innovations she introduced to the children's ward, survey her groundbreaking research, that examined the influence of the Beit Shean Valley climate on infant development. Her conclusions dramatically affected the treatment and upbringing of children in that climate, and were adopted not only in local kibbutzim but throughout the country. PMID:26380468

  3. DR Resources for Energy and Ancillary Services in the West (Presentation)

    SciTech Connect

    Hummon, M.; Kiliccote, S.

    2014-04-01

    Demand response (DR) resources present a potentially important source of grid flexibility however, DR in grid models is limited by data availability and modeling complexity. This presentation focuses on the co-optimization of DR resources to provide energy and ancillary services in a production cost model of the Colorado "test system". We assume each DR resource can provide energy services by either shedding load or shifting its use between different times, as well as operating reserves: frequency regulation, contingency reserve, and flexibility (or ramping) reserve. There are significant variations in the availabilities of different types of DR resources, which affect both the operational savings as well as the revenue for each DR resource. The results presented include the system-wide avoided fuel and generator start-up costs as well as the composite revenue for each DR resource by energy and operating reserves.

  4. STS-72 Mission Specialist Dr. Daniel T. Barry suits up

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Looking elated at the prospect of his upcoming spaceflight, STS- 72 Mission Specialist Dr. Daniel T. Barry dons his launch/entry suit in the Operations and Checkout Building with assistance from a suit technician. The trip into space will be the first for Barry, a medical doctor who also has a Ph.D. in electrical engineering. He and five fellow crew members will soon depart for Launch Pad 39, where the Space Shuttle Endeavour is undergoing final preparations for liftoff during an approximately 49-minute window opening at about 4:18 am EST, January 11.

  5. STS-71 Payload Commander Dr. Ellen S. Baker suits up

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-71 Payload Commander Dr. Ellen S. Baker is assisted by a suit technician as she dons her launch/entry suit in the Operations and Checkout Building. Her third spaceflight will be an historic one for Baker, a medical doctor, as she oversees the series of scientific investigations that will be conducted during the first docking of the U.S. Space Shuttle to the Russian Space Station Mir. Baker and six fellow crew members -- four Americans and two Russian cosmonauts -- will shortly depart for Launch Pad 39A, where the Space Shuttle Atlantis awaits liftoff during a 10- minute launch window opening at 3:32 p.m. EDT.

  6. Dr. Christopher Kraft looks over packaged 'parasol' in bldg 10

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Dr. Christopher C. Kraft J. (left), JSC Director, and George A Post, JSC Crew Systems Division, look over the packaged 'parasol' during fabrication and checkout of the umbrella-like mechanical device in the Technical Services shop in bldg 10 at JSC. The 'parasol' is designed to fit into the T027 experiment photometer canister. The canopy portion of the 'parasol' measures 24 feet by 22 feet. The 'parasol' is one of several sunscreen possibilities being considered for use in shading the overheated Skylab 1 Orbital Workshop.

  7. 89. View of DR 2 antenna (structure no. 736) at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    89. View of DR 2 antenna (structure no. 736) at 65 percent completion showing erection process. Antenna system designed and factory construction by D.S. Kennedy & Company., Comasset, MA, 1958. Note scanner radar building in background. Official photograph BMEWS Project by unknown photographer, 11 July, 1960, Photographic Services, Riverton, NJ, BMEWS, clear as negative no. A-824. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  8. Rapidity: The Special Relativity Work of Dr. Vladimir Karapetoff

    NASA Astrophysics Data System (ADS)

    Carter, Hamilton

    2014-03-01

    Between 1924 and 1944 Dr. Vladimir Karapetoff, a professor in the electrical engineering department of Cornell University, authored 11 papers on the topic of special relativity. While his initial papers focused on the then popular oblique angle treatment of special relativity, he soon became a vocal proponent of performing special relativistic calculations using rapidity, a technique that emphasizes the hyperbolic geometric nature of Minkowski space-time. While rapidity has fallen out of usage with the exception of a specialized dialect within particle physics, it offers interesting technical and pedagogical perspectives on the geometrical nature of space-time not evident in the present day relativistic parlance.

  9. Progress in inflammatory neuropathy -the legacy of Dr Jack Griffin.

    PubMed

    Feldman, Eva L; Hughes, Richard A C; Willison, Hugh J

    2015-11-01

    The past quarter of a century has brought incredible advances in our understanding of inflammatory neuropathies, and the insights into Guillain-Barré syndrome (GBS) began in the 1990s with the seminal work of Dr Jack Griffin and his colleagues. In this essay, we provide a tribute to Jack, and review the recent progress in a field that he termed his personal favourite. In particular, we discuss the new developments in our understanding and diagnosis of inflammatory neuropathies, the recent emergence of the node of Ranvier and the paranode as sites of intensive investigation, and the mechanistic evidence that is providing a platform for therapeutic development studies. PMID:26458287

  10. Dr. von Braun and Army Ballistics Missile Agency (ABMA) Group

    NASA Technical Reports Server (NTRS)

    1959-01-01

    This photograph of Dr. von Braun, shown here to the left of General Bruce Medaris, was taken in the fall of 1959, immediately prior to Medaris' retirement from the Army. At the time, von Braun and his associates worked for the Army Ballistics Missile Agency in Huntsville, Alabama. Those in the photograph have been identified as Ernst Stuhlinger, Frederick von Saurma, Fritz Mueller, Hermarn Weidner, E.W. Neubert (partially hidden), W.A. Mrazek, Karl Heimburg, Arthur Rudolph, Otto Hoberg, von Braun, Oswald Lange, Medaris, Helmut Hoelzer, Hans Maus, E.D. Geissler, Hans Heuter, and George Constan.

  11. Clinical and molecular studies in full trisomy 22: Further delineation of the phenotype and review of the literature. Reply to Dr. Robinson and Dr. Kalousek

    SciTech Connect

    Bacino, C.A.; Graham, J.M. Jr.

    1996-03-01

    This {open_quotes}Letter to the Editor{close_quotes} responds to the comments by Dr. Robinson and Dr. Kalousek regarding the implications of meiotic versus somatic chromosomal aberrations. The survival time of the patient may depend on the detection of mosicism; the discussion of the existence of full trisomy 22 remains controversial. 2 refs.

  12. The Chicago Board of Education Desegregation Policies and Practices [1975-1985]: A Historical Examination of the Administrations of Superintendents Dr. Joseph P. Hannon and Dr. Ruth Love

    ERIC Educational Resources Information Center

    James, Michael

    2009-01-01

    The purpose of this study will be to examine the policies and practices of two distinguished superintendents of the Chicago Public Schools: Dr. Joseph P. Hannon and the first African American female Superintendent Dr. Ruth Love. Hannon's four year administration extended from 1975 through 1979. Love's administration encompassed the years 1980…

  13. Financial management of hospitals.

    PubMed

    Speranzo, A J

    1984-05-01

    The effect of hospital reimbursement systems on the financial management of hospitals is briefly discussed, and the organization of hospital financial operations is reviewed. The implementation of Medicare prospective pricing will change the way in which hospital finances are managed. Health-care managers will be concerned with the profitability of product lines, or diagnosis-related groups, in future strategic planning efforts. The hospital's finance department consists of several traditional areas that exist in almost all financial organizations. The functions and interactions of these various areas are discussed in light of previous and current hospital reimbursement strategies. Staffing of the finance department and the duties of the hospital's chief financial officer are also described. The prospective pricing system of hospital reimbursement and increasing pressure from the business community to stem the rising costs of health care will produce changes in the medical and financial operations of the hospital industry over the next decade. PMID:6375357

  14. Hospital demand for physicians.

    PubMed

    Morrisey, M A; Jensen, G A

    1990-01-01

    This article develops a derived demand for physicians that is general enough to encompass physician control, simple profit maximization and hospital utility maximization models of the hospital. The analysis focuses on three special aspects of physician affiliations: the price of adding a physician to the staff is unobserved; the physician holds appointments at multiple hospitals, and physicians are not homogeneous. Using 1983 American Hospital Association data, a system of specialty-specific demand equations is estimated. The results are consistent with the model and suggest that physicians should be concerned about reduced access to hospitals, particularly as the stock of hospitals declines. PMID:10104050

  15. Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice.

    PubMed

    Link, Jason M; Rich, Cathleen M; Korat, Maya; Burrows, Gregory G; Offner, Halina; Vandenbark, Arthur A

    2007-04-01

    Treatment of human autoimmune diseases such as multiple sclerosis (MS) will likely require agents that can prevent or reverse the inflammatory process that results in clinical relapses and disease progression. We evaluated the ability of a newly designed monomeric recombinant TCR ligand (RTL342M) containing HLA-DR2 peptide-binding domains covalently linked to MOG-35-55 peptide to prevent and treat both the initial episode and subsequent relapses of experimental autoimmune encephalomyelitis (EAE) in HLA-DR2 transgenic mice. Single doses of RTL342M given either i.v. or s.c. to HLA-DR2 mice produced a rapid (within 24 h) and dose-dependent reversal of clinical signs of paralytic EAE, and even a single dose < or = 2 microg could produce a significant treatment effect. Multiple daily doses were even more effective than the same total amount of RTL given as a single dose. By establishing the minimal effective dose, we determined that RTLs may be 50 times more potent than molar equivalent doses of myelin peptide alone. RTL342M given prior to induction of EAE prevented disease in most mice, and the remainder could be successfully retreated with RTL. Most important for clinical application, RTL342M was highly effective for treating EAE relapses when given periodically prior to the relapse or even after relapses had occurred. These data demonstrate the rapid and potent clinical effects of RTL342M at disease onset and during relapses in EAE and establish important principles governing the application of this novel approach as a possible therapy for patients with MS. PMID:17257899

  16. Hospitable Classrooms: Biblical Hospitality and Inclusive Education

    ERIC Educational Resources Information Center

    Anderson, David W.

    2011-01-01

    This paper contributes to a Christian hermeneutic of special education by suggesting the biblical concept of hospitality as a necessary characteristic of classroom and school environments in which students with disabilities and other marginalized students can be effectively incorporated into the body of the classroom. Christian hospitality, seen…

  17. PREFACE: Eighth International Conference on Dissociative Recombination (DR2010)

    NASA Astrophysics Data System (ADS)

    Guberman, Steven L.; Orel, Ann E.

    2011-07-01

    In dissociative recombination (DR), a molecular ion captures an electron and falls apart. One might initially conclude that this process is relatively simple. However, a review of the DR literature over the past 60 years, since the pioneering papers of Sir David Bates [1], shows that the study of DR has proved to be highly challenging for both theorists and experimentalists. Both this challenge and the ubiquitous importance of the process have made its study rewarding, endlessly interesting, and full of surprises. DR is fundamentally the interaction of an electronic continuum with a vibrational continuum often connected by quasibound intermediate states. Autoionization in the first continuum competes with dissociation in the second. DR occurs at the total energy of an ion plus a free electron and is in the same region as vibrationally excited Rydberg states and other neutral superexcited states. All these states interact with each other prior to dissociation, forming a complex that controls the quantum yields of products. The complexity of the process has required both innovation and ingenuity on the part of both theorists and experimentalists. Over the years, it has become apparent that in order to compare theoretical and experimental results, the experiments must identify the electronic, vibrational and for low mass ions, the rotational state. The traditional disagreement between theoretical and experimental results has been due, in part, to the sensitivity of DR cross sections and rate constants to the state of the recombining ion. Great progress has been made in recent years in both flowing afterglow and storage ring experiments aimed at reducing this uncertainty. The latest advances and insights in theory and experiment were the topics of the Eighth International Conference on Dissociative Recombination held at the Granlibakken Lodge at Lake, Tahoe, California, 16-20 August 2010. The conference was part of a series of conferences on DR that started at Chateau

  18. CENSUS OF BLUE STARS IN SDSS DR8

    SciTech Connect

    Scibelli, Samantha; Newberg, Heidi Jo; Carlin, Jeffrey L.; Yanny, Brian

    2015-01-01

    We present a census of the 12,060 spectra of blue objects ((g – r){sub 0} < –0.25) in the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8). As part of the data release, all of the spectra were cross-correlated with 48 template spectra of stars, galaxies, and QSOs to determine the best match. We compared the blue spectra by eye to the templates assigned in SDSS DR8. 10,856 of the objects matched their assigned template, 170 could not be classified due to low signal-to-noise ratio, and 1034 were given new classifications. We identify 7458 DA white dwarfs, 1145 DB white dwarfs, 273 rarer white dwarfs (including carbon, DZ, DQ, and magnetic), 294 subdwarf O stars, 648 subdwarf B stars, 679 blue horizontal branch stars, 1026 blue stragglers, 13 cataclysmic variables, 129 white dwarf-M dwarf binaries, 36 objects with spectra similar to DO white dwarfs, 179, quasi-stellar objects (QSOs), and 10 galaxies. We provide two tables of these objects, sample spectra that match the templates, figures showing all of the spectra that were grouped by eye, and diagnostic plots that show the positions, colors, apparent magnitudes, proper motions, etc., for each classification. Future surveys will be able to use templates similar to stars in each of the classes we identify to automatically classify blue stars, including rare types.

  19. M-giant star candidates identified in LAMOST DR 1

    NASA Astrophysics Data System (ADS)

    Zhong, Jing; Lépine, Sébastien; Li, Jing; Chen, Li; Hou, Jin-Liang; Yang, Ming; Li, Guang-Wei; Zhang, Yong; Hou, Yong-Hui

    2015-08-01

    We perform a discrimination procedure with the spectral index diagram of TiO5 and CaH2+CaH3 to separate M giants from M dwarfs. Using the M giant spectra identified from LAMOST DR1 with high signal-to-noise ratio, we have successfully assembled a set of M giant templates, which show more reliable spectral features. Combining with the M dwarf/subdwarf templates in Zhong et al., we present an extended library of M-type templates which includes not only M dwarfs with a well-defined temperature and metallicity grid but also M giants with subtypes from M0 to M6. Then, the template-fitting algorithm is used to automatically identify and classify M giant stars from LAMOST DR1. The resulting catalog of M giant stars is cross-matched with 2MASS JHKs and WISE W1/W2 infrared photometry. In addition, we calculated the heliocentric radial velocity of all M giant stars by using the cross-correlation method with the template spectrum in a zero-velocity rest frame. Using the relationship between the absolute infrared magnitude MJ and our classified spectroscopic subtype, we derived the spectroscopic distance of M giants with uncertainties of about 40%. A catalog of 8639 M giants is provided. As an additional result of this analysis, we also present a catalog of 101 690 M dwarfs/subdwarfs which are processed by our classification pipeline.

  20. Census of Blue Stars in SDSS DR8

    NASA Astrophysics Data System (ADS)

    Scibelli, Samantha; Newberg, Heidi Jo; Carlin, Jeffrey L.; Yanny, Brian

    2014-12-01

    We present a census of the 12,060 spectra of blue objects ((g - r)0 < -0.25) in the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8). As part of the data release, all of the spectra were cross-correlated with 48 template spectra of stars, galaxies, and QSOs to determine the best match. We compared the blue spectra by eye to the templates assigned in SDSS DR8. 10,856 of the objects matched their assigned template, 170 could not be classified due to low signal-to-noise ratio, and 1034 were given new classifications. We identify 7458 DA white dwarfs, 1145 DB white dwarfs, 273 rarer white dwarfs (including carbon, DZ, DQ, and magnetic), 294 subdwarf O stars, 648 subdwarf B stars, 679 blue horizontal branch stars, 1026 blue stragglers, 13 cataclysmic variables, 129 white dwarf-M dwarf binaries, 36 objects with spectra similar to DO white dwarfs, 179, quasi-stellar objects (QSOs), and 10 galaxies. We provide two tables of these objects, sample spectra that match the templates, figures showing all of the spectra that were grouped by eye, and diagnostic plots that show the positions, colors, apparent magnitudes, proper motions, etc., for each classification. Future surveys will be able to use templates similar to stars in each of the classes we identify to automatically classify blue stars, including rare types.

  1. Pathogenesis of Human Diffusely Adhering Escherichia coli Expressing Afa/Dr Adhesins (Afa/Dr DAEC): Current Insights and Future Challenges

    PubMed Central

    2014-01-01

    SUMMARY The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as “silent pathogens” with the capacity to emerge as “pathobionts” for the development of inflammatory bowel disease and intestinal carcinogenesis. PMID:25278576

  2. A reconstructive surgeon's taste in art: Dr Peter Parker and the Lam Qua oil paintings.

    PubMed

    Chang, J

    1993-05-01

    Hidden within the basement archives of Yale University's Historical Medical Library lie the original oil painting collection and personal papers of the first American surgeon to practice in China. The Reverend Dr Peter Parker, a graduate of Yale, established the first American hospital in Guangzhou (formerly Canton) in 1835 and successfully introduced Western surgical techniques including amputation, anesthesia, and reconstructive surgery. In addition to this distinguished career of medical missionary service, Parker commissioned the Chinese artist Lam Qua to paint a fascinating series of portraits depicting patients with extreme tumor growths. In this article, Parker's own journals are examined to reveal both his missionary zeal and his frustrations working in China. Selected examples of the Lam Qua paintings are presented along with Parker's corresponding patient descriptions. These detailed patient reports give insight into the extent of surgical pathology as well as the relative brutality of surgical techniques in the early to mid-1800s. The historical significance of the Peter Parker-Lam Qua collaboration within the context of the Western transformation of Chinese art and medicine is also discussed. PMID:8342936

  3. The application of hospitality elements in hospitals.

    PubMed

    Wu, Ziqi; Robson, Stephani; Hollis, Brooke

    2013-01-01

    In the last decade, many hospital designs have taken inspiration from hotels, spurred by factors such as increased patient and family expectations and regulatory or financial incentives. Increasingly, research evidence suggests the value of enhancing the physical environment to foster healing and drive consumer decisions and perceptions of service quality. Although interest is increasing in the broader applicability of numerous hospitality concepts to the healthcare field, the focus of this article is design innovations, and the services that such innovations support, from the hospitality industry. To identify physical hotel design elements and associated operational features that have been used in the healthcare arena, a series of interviews with hospital and hotel design experts were conducted. Current examples and suggestions for future hospitality elements were also sought from the experts, academic journals, and news articles. Hospitality elements applied in existing hospitals that are addressed in this article include hotel-like rooms and decor; actual hotels incorporated into medical centers; hotel-quality food, room service, and dining facilities for families; welcoming lobbies and common spaces; hospitality-oriented customer service training; enhanced service offerings, including concierges; spas or therapy centers; hotel-style signage and way-finding tools; and entertainment features. Selected elements that have potential for future incorporation include executive lounges and/or communal lobbies with complimentary wireless Internet and refreshments, centralized controls for patients, and flexible furniture. Although the findings from this study underscore the need for more hospitality-like environments in hospitals, the investment decisions made by healthcare executives must be balanced with cost-effectiveness and the assurance that clinical excellence remains the top priority. PMID:23424818

  4. Alloantiserum recognizing a DQw2 split which is associated with DR3.

    PubMed

    Flesch, B; Neppert, J; Ziegler, P; Achtert, G

    1991-01-01

    A typing serum MUE 38539 II, was found to recognize a DR3-associated split of DQw2. In cytotoxicity tests, MUE 38539 II yielded positive test results with B lymphocytes but not with monocytes of DR3-positive cell donors. This was in contrast to other typing reagents for DR3 that react with B lymphocytes as well as monocytes. Lymphocytotoxicity tests using MUE 38539 II were negative with DR7- and DQw2-positive cells. The assumption that the serum recognizes a DR3-associated split of DQw2, and not DR3 itself, was confirmed by the lack of reactivity with a DQw4- and DR3-positive lymphoblastoid cell line (RSH). The assumption was also corroborated using reagents from a family in which DR3 and DQw2 were not found in the usually described linkage. In two lines, DR3 was associated with DQw- (2707 and 2710), and in the cell line 2704, DQw2 was associated with DRw-. The serum MUE 38539 II was exclusively cytotoxic with lymphoblastoid cell lines from those family members who were positive for DQw2, independently of the DR3 antigens of the cells. PMID:2031339

  5. Hospital-acquired pneumonia

    MedlinePlus

    ... this page: //medlineplus.gov/ency/article/000146.htm Hospital-acquired pneumonia To use the sharing features on this page, please enable JavaScript. Hospital-acquired pneumonia is an infection of the lungs ...

  6. Surviving Your Child's Hospitalization.

    ERIC Educational Resources Information Center

    Cohen, David A.

    1988-01-01

    The parent of a young child who required major open heart surgery shares his suggestions for coping with a young child's hospitalization including parent visitation, relating to the hospital staff, getting answers to questions, and utilizing available services. (DB)

  7. Understanding your hospital bill

    MedlinePlus

    ... getting the help you need, consider hiring a medical-billing advocate. Advocates charge an hourly fee or a ... American Hospital Association. Hospital Billing and Collection ... 15, 2015. Family Doctor.org. Understanding your Medical Bills. ...

  8. Hospitals as health educators

    MedlinePlus

    ... than your local hospital. From health videos to yoga classes, many hospitals offer information families need to ... care and breastfeeding Parenting Baby sign language Baby yoga or massage Babysitting courses for teens Exercise classes ...

  9. [Dr. Piotr Borsukiewicz--one of the pleiad of physicians in Lublin (the 75th anniversary of his death)].

    PubMed

    Staszyc, J

    1992-01-01

    Seventy years have passed since the death of dr Piotr Borsukiewicz. He spent 9 out of his 22 years of work in Lublin (1909-1918) being the head of the paediatric hospital (1911-1918), the member of the Lublin Medical Society, the president and vice president of some other public service organizations and inscribed himself in letters of gold in the history of medicine and people of Lublin. He worked and lived in the difficult years of two wars (1904-1905 and 1914-1918), the rapid development of medical sciences and the separation of medical specialties. His diligence, loyalty to the Hippocratic code and the instructions of dr W. Biegański as well as to the patriotic dictates resulted in the union of the meaning of his own existence with the deep belief in man and the favourite work as a physician. Helping the poor and those in need he contracted spotted fever but belittled his complaints and died on April 12, 1918 in Lublin. He left us the special patterns of the ideal medical care which are still alive today, so non omnis moriar. PMID:1365791

  10. HLA-A, -B, -C, -DR, and -DQ Matching in Pancreas Transplantation: Effect on Graft Rejection and Survival.

    PubMed

    Rudolph, E N; Dunn, T B; Mauer, D; Noreen, H; Sutherland, D E R; Kandaswamy, R; Finger, E B

    2016-08-01

    To enhance selection of appropriate deceased donors for pancreas transplants, we sought to determine whether HLA matching improved posttransplantation outcomes. In this single-center study of 1219 pancreas transplants, we correlated posttransplantation outcomes with HLA-A, -B, -C, -DR, and -DQ matches and mismatches. Rejection was linearly correlated with the number of mismatches. The individual number of HLA mismatches reached significance at four or more with a 2.3- to 2.9-fold increase in rejection. The effect was most predominant with HLA-B (1.8-fold with one mismatch and 2.0-fold with two mismatches) and -DR (1.9-fold with two mismatches) loci, whereas HLA-A, -C, and -DQ matches or mismatches did not independently predict acute rejection. The affect was strongest in solitary pancreas transplants, with little impact for simultaneous pancreas and kidney (SPK). In contrast, HLA matching did not affect graft or patient survival rates but was associated with a reduced risk of opportunistic infection. Avoidance of acute rejection saved an estimated $32 000 for solitary pancreas recipients and $52 000 for SPK recipients in hospital costs. Our data do not support the use of HLA matching for predicting pancreas graft survival but do support its significance for the reduction of acute rejection, particularly for solitary pancreas recipients. PMID:26814363

  11. [Story of three SS dentists during World War II: Pr Hugo Blaschke, Dr Hermann Pook and Dr Willy Frank].

    PubMed

    Riaud, Xavier

    2006-12-01

    This story of three SS dentists shows very clearly that the medical code of ethics, under a totalitarian regime, ends where ideology begins. Professor Hugo Blaschke provided dental care to the most eminent Nazi leaders, but he also was the senior SS dentist. He was in charge of dental care in the Waffen-SS, and therefore, he had responsibility for the stocks of dental gold collected from the mouths of those who died in the concentration camps, in order to make dentures for his soldiers. Dr Hermann Pook was the dentist in charge of all the other dentists practising in the concentration camps. He was responsible for gathering statistics on the dental care provided for prisoners in the camps. His instructions were very clear: "No conservation or restorative treatment. Only extractions, and with no anaesthesia!" He was also in charge of gathering the gold that was collected in the camps, for the financial department of the SS. Dr Willy Frank, an Auschwitz dentist, took part in the selection of some of the convoys for the gas chambers. His participation in the collection of gold from the mouths of the dead was also established. These three men were sentenced to prison for War Crimes and Crimes against Humanity. PMID:17575817

  12. Association of HLA-Bw46DR9 combination with juvenile myasthenia gravis in Chinese.

    PubMed Central

    Chen, W H; Chiu, H C; Hseih, R P

    1993-01-01

    One hundred and fifty two Chinese patients with myasthenia gravis in Taiwan were investigated for HLA-A, B, C and DR/DQ typing. HLA-Bw46 and DR9 frequencies were significantly increased in patients compared with the control group, and there was a decrease in DR3. Further analysis between different subgroups of patients showed Bw46 and DR9 were more significantly increased in the juvenile group than in the adult group. No single HLA allele was associated with either clinical type or thymic pathology, but there was an excess of BW46DR9 combination in both juvenile and ocular type patients. The Chinese population with myasthenia gravis is characterised by earlier age at onset, more ocular forms and less clinically severe illness than in whites, and these characteristics indicate a special subgroup that correlates with the strong Bw46DR9 association. PMID:8482958

  13. 2. View northwest of main hospital building complex, hospital building ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. View northwest of main hospital building complex, hospital building (Building 90), administration and clinical hospital building (Building 88), and hospital building (Building 91) - National Home for Disabled Volunteer Soldiers Western Branch, 4101 South Fourth Street, Leavenworth, Leavenworth County, KS

  14. The Chymistry of "The Learned Dr Plot" (1640-96).

    PubMed

    Roos, Anna Marie

    2014-01-01

    In the seventeenth century, there were developing norms of openness in the presentation of scientific knowledge that were at odds with traditions of secrecy among chymists, particularly practitioners of chrysopoeia, or the transmutation of metals. This chapter analyzes how Dr. Robert Plot, the first professor of chymistry at Oxford, negotiated these boundaries within an institutional context. I first delineate his chymical and experimental practice, which incorporated procedures from medieval alchemical sources, particularly the Lullian corpus, as well as more novel practices from seventeenth-century chymistry. Then, I analyze how personal and institutional ambitions and economic considerations shaped to what extent Plot negotiated the boundaries between secrecy and the public dissemination of chymical knowledge. PMID:26103749

  15. Dr. Cheryl Nickerson studies Salmonella in simulated low-g

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Dr. Cheryl Nickerson of Tulane University is studying the effects of simulated low-g on a well-known pathogen, Salmonella typhimurium, a bacterium that causes two to four million cases of gastrointestinal illness in the United States each year. While most healthy people recover readily, S. typhimurium can kill people with weakened immune systems. Thus, a simple case of food poisoning could disrupt a space mission. Using the NASA rotating-wall bioreactor, Nickerson cultured S. typhimurium in modeled microgravity. Mice infected with the bacterium died an average of three days faster than the control mice, indicating that S. typhimurium's virulence was enhanced by the bioreactor. Earlier research showed that 3 percent of the genes were altered by exposure to the bioreactor. Nickerson's work earned her a 2001 Presidential Early Career Award for Scientists and Engineers.

  16. Dr. Richard Grugel examines an ampoule of a succinonitrile mixture

    NASA Technical Reports Server (NTRS)

    2003-01-01

    On Earth when scientists melt metals, bubbles that form in the molten material can rise to the surface, pop and disappear. In microgravity -- the near-weightless environment created as the International Space Station orbits Earth -- the lighter bubbles do not rise and disappear. Prior space experiments have shown that bubbles often become trapped in the final metal or crystal sample -similar to the bubbles trapped in this sample. In the solid, these bubbles, or porosity, are defects that diminish both the material's strength and usefulness. The Pore Formation and Mobility Investigation will melt samples of a transparent modeling material, succinonitrile and succinonitrile water mixtures, shown here in an ampoule being examined by Dr. Richard Grugel, the principal investigator for the experiment at NASA's Marshall Space Flight Center in Huntsville, Ala. As the samples are processed in space, Grugel will be able to observe how bubbles form in the samples and study their movements and interactions.

  17. GPS/DR Error Estimation for Autonomous Vehicle Localization.

    PubMed

    Lee, Byung-Hyun; Song, Jong-Hwa; Im, Jun-Hyuck; Im, Sung-Hyuck; Heo, Moon-Beom; Jee, Gyu-In

    2015-01-01

    Autonomous vehicles require highly reliable navigation capabilities. For example, a lane-following method cannot be applied in an intersection without lanes, and since typical lane detection is performed using a straight-line model, errors can occur when the lateral distance is estimated in curved sections due to a model mismatch. Therefore, this paper proposes a localization method that uses GPS/DR error estimation based on a lane detection method with curved lane models, stop line detection, and curve matching in order to improve the performance during waypoint following procedures. The advantage of using the proposed method is that position information can be provided for autonomous driving through intersections, in sections with sharp curves, and in curved sections following a straight section. The proposed method was applied in autonomous vehicles at an experimental site to evaluate its performance, and the results indicate that the positioning achieved accuracy at the sub-meter level. PMID:26307997

  18. GPS/DR Error Estimation for Autonomous Vehicle Localization

    PubMed Central

    Lee, Byung-Hyun; Song, Jong-Hwa; Im, Jun-Hyuck; Im, Sung-Hyuck; Heo, Moon-Beom; Jee, Gyu-In

    2015-01-01

    Autonomous vehicles require highly reliable navigation capabilities. For example, a lane-following method cannot be applied in an intersection without lanes, and since typical lane detection is performed using a straight-line model, errors can occur when the lateral distance is estimated in curved sections due to a model mismatch. Therefore, this paper proposes a localization method that uses GPS/DR error estimation based on a lane detection method with curved lane models, stop line detection, and curve matching in order to improve the performance during waypoint following procedures. The advantage of using the proposed method is that position information can be provided for autonomous driving through intersections, in sections with sharp curves, and in curved sections following a straight section. The proposed method was applied in autonomous vehicles at an experimental site to evaluate its performance, and the results indicate that the positioning achieved accuracy at the sub-meter level. PMID:26307997

  19. Dr. Cheryl Nickerson studying Salmonella at Tulane University

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Dr. Cheryl Nickerson (right) of Tulane University is studying the effects of simulated low-g on a well-known pathogen, Salmonella typhimurium, a bacterium that causes two to four million cases of gastrointestinal illness in the United States each year. While most healthy people recover readily, S. typhimurium can kill people with weakened immune systems. Thus, a simple case of food poisoning could disrupt a space mission. Using the NASA rotating-wall bioreactor, Nickerson cultured S. typhimurium in modeled microgravity. Mice infected with the bacterium died an average of three days faster than the control mice, indicating that S. typhimurium's virulence was enhanced by the bioreactor. Earlier research showed that 3 percent of the genes were altered by exposure to the bioreactor. Nickerson's work earned her a 2001 Presidential Early Career Award for Scientists and Engineers.

  20. In Memoriam: Prof. Dr Dragutin Djurovic (1937-2013)

    NASA Astrophysics Data System (ADS)

    2013-12-01

    Prof. dr Dragutin Djurovic was born in Guca, Serbia, on December 20, 1937. He completed his primary and secondary education in Guca and Cacak. In the period 1956-1958, he studied at the General Military Academy in Belgrade. He enrolled at the Faculty of Sciences and Mathematics - Astronomy Group in 1958 and graduated in 1963. After graduation he went to study visits to Paris (1966) and Bruxelles (1972 and 1975). He obtained his MSc degree in 1970 from the University of Belgrade with a thesis entitled "Application of different types of telescopes for astronomical determination of time". His supervisor for the master thesis was Prof. Zaharije Brkic. Dragutin Djurovic defended his PhD thesis "Contribution to determination of Earth-rotation variations and polar motion" at the University of Belgrade in 1974. Most of the thesis-related research was done in Bruxelles during 1972 under the supervision of Prof. Paul Melchior.

  1. Dr. Newell Sill Jenkins: progenitor of cosmetic dentistry.

    PubMed

    Hyson, John M; Swank, Scott D

    2003-08-01

    Dr. Newell Sill Jenkins was one of the pioneer American dentists who took "American dentistry" to Europe. Among his patients were Composer Richard Wagner, and among his friends, Author Mark Twain. He treated some of the crown head of Europe, and yet found time to participate in organized dentistry and conduct research in cosmetic dentistry. He was the father of the porcelain revival in both Europe and America. Unfortunately, Jenkins' Legacy as the chief proponent of cosmetic dentistry in the late 19th and early 20th centuries has been largely ignored by dental historians. In a 20-year period (1896 to 1916), Jenkins published 32 articles in the dental literature on the esthetic advantages of porcelain fillings. It is time to give Jenkins his just recognition. PMID:13677405

  2. [DR image denoising based on Laplace-Impact mixture model].

    PubMed

    Feng, Guo-Dong; He, Xiang-Bin; Zhou, He-Qin

    2009-07-01

    A novel DR image denoising algorithm based on Laplace-Impact mixture model in dual-tree complex wavelet domain is proposed in this paper. It uses local variance to build probability density function of Laplace-Impact model fitted to the distribution of high-frequency subband coefficients well. Within Laplace-Impact framework, this paper describes a novel method for image denoising based on designing minimum mean squared error (MMSE) estimators, which relies on strong correlation between amplitudes of nearby coefficients. The experimental results show that the algorithm proposed in this paper outperforms several state-of-art denoising methods such as Bayes least squared Gaussian scale mixture and Laplace prior. PMID:19938519

  3. Sunlight at Southall Green. Dr. Ingen Housz discovers photosynthesis.

    PubMed

    Norman; Beale, E

    2001-01-01

    In the following fictitious conversation, Dr. Jan Ingen Housz (1730-1799), the Dutch physician and natural philosopher, describes to William Temple Franklin (1760-1823), the grandson of Benjamin Franklin, how in 1779 he discovered the paramount role of sunlight in what we now call photosynthesis (Wiesner 1905; Van der Pas 1981; Reed 1949; Beale and Beale 1999). The two men, together with the English law reformer Samuel Romilly, were dinner guests of the First Marquis of Lansdowne at Lansdowne House on Wednesday 2 February 1791 (Bowood House Archives 1791). As far as possible we use their own recorded words and phrases, employing surviving manuscripts as a lexicon. Additional biographical and geographical details are provided in an Appendix, and all sources are listed in the References. PMID:11482003

  4. A 10,000 YEAR OLD EXPLOSION IN DR21

    SciTech Connect

    Zapata, Luis A.; Perez-Goytia, Nadia; Rodriguez, Luis F.; Loinard, Laurent; Schmid-Burgk, Johannes; Ho, Paul T. P.; Cruz-Gonzalez, Irene

    2013-03-10

    Sensitive high angular resolution ({approx}2'') CO(2-1) line observations made with the Submillimeter Array of the flow emanating from the high-mass star-forming region DR21 located in the Cygnus X molecular cloud are presented. These new interferometric observations indicate that this well known enigmatic outflow appears to have been produced by an explosive event that took place about 10,000 years ago, and that might be related to the disintegration of a massive stellar system such as the one that occurred in Orion Becklin-Neugebauer/Kleinman-Low 500 years ago, but about 20 times more energetic. This result therefore argues in favor of the idea that the disintegration of young stellar systems perhaps is a frequent phenomenon present during the formation of massive stars. However, many more theoretical and observational studies are still needed to confirm our hypothesis.

  5. User's Manual for FEMOM3DR. Version 1.0

    NASA Technical Reports Server (NTRS)

    Reddy, C. J.

    1998-01-01

    FEMoM3DR is a computer code written in FORTRAN 77 to compute radiation characteristics of antennas on 3D body using combined Finite Element Method (FEM)/Method of Moments (MoM) technique. The code is written to handle different feeding structures like coaxial line, rectangular waveguide, and circular waveguide. This code uses the tetrahedral elements, with vector edge basis functions for FEM and triangular elements with roof-top basis functions for MoM. By virtue of FEM, this code can handle any arbitrary shaped three dimensional bodies with inhomogeneous lossy materials; and due to MoM the computational domain can be terminated in any arbitrary shape. The User's Manual is written to make the user acquainted with the operation of the code. The user is assumed to be familiar with the FORTRAN 77 language and the operating environment of the computers on which the code is intended to run.

  6. The UV-bright Quasar Survey (UVQS): DR1

    NASA Astrophysics Data System (ADS)

    Monroe, TalaWanda R.; Prochaska, J. Xavier; Tejos, Nicolas; Worseck, Gabor; Hennawi, Joseph F.; Schmidt, Tobias; Tumlinson, Jason; Shen, Yue

    2016-07-01

    We present the first data release (DR1) from our UV-bright Quasar Survey for new z ∼ 1 active galactic nuclei (AGNs) across the sky. Using simple GALEX UV and WISE near-IR color selection criteria, we generated a list of 1450 primary candidates with FUV < 18.5 mag. We obtained discovery spectra, primarily on 3 m-class telescopes, for 1040 of these candidates and confirmed 86% as AGNs, with redshifts generally at z > 0.5. Including a small set of observed secondary candidates, we report the discovery of 217 AGNs with FUV < 18 mag that previously had no reported spectroscopic redshift. These are excellent potential targets for UV spectroscopy before the end of the Hubble Space Telescope mission. The main data products are publicly available through the Mikulski Archive for Space Telescopes.

  7. Dr. von Braun Standing by Five F-1 Engines

    NASA Technical Reports Server (NTRS)

    2004-01-01

    A pioneer of America's space program, Dr. von Braun stands by the five F-1 engines of the Saturn V launch vehicle. This Saturn V vehicle is an actual test vehicle which has been displayed at the U.S. Space Rocket Center in Huntsville, Alabama. Designed and developed by Rocketdyne under the direction of the Marshall Space Flight Center, a cluster of five F-1 engines was mounted on the Saturn V S-IC (first) stage. The engines measured 19-feet tall by 12.5-feet at the nozzle exit and burned 15 tons of liquid oxygen and kerosene each second to produce 7,500,000 pounds of thrust. The S-IC stage is the first stage, or booster, of a 364-foot long rocket that ultimately took astronauts to the Moon.

  8. Chemical Cartography with SDSS-III APOGEE: DR12 Results

    NASA Astrophysics Data System (ADS)

    Hayden, Michael R.; Holtzman, Jon A.; Bovy, Jo; Majewski, Steven R.; Nidever, David L.; Zasowski, Gail; Schiavon, Ricardo P.; Frinchaboy, Peter M.; Hearty, Fred; Allende-Prieto, Carlos; García Pérez, Ana; Robin, Annie; Cunha, Katia M. L.; Beers, Timothy C.; Apogee Team

    2015-01-01

    The SDSS-III Apache Point Observatory Galactic Evolution Experiment (APOGEE) spectrograph provides an unprecedented view of the Milky Way disk, due in part to its ability to observe in the infrared, where the effects of extinction are significantly reduced compared to optical surveys. We present updated results on mean metallicity and chemical abundance gradients using the full three years of APOGEE1 observations and new results of the metallicity distribution function (MDF) and the [α/Fe] vs. [Fe/H] plane at different locations in the Milky Way disk. Our sample comprises nearly high signal-to-noise observations of nearly 100,000 red giant stars taken from SDSS DR12. These observations span the entire Milky Way visible from the northern hemisphere, ranging from the bulge to the edge of the disk (0

  9. Influence of non-inherited maternal HLA-DR antigens on susceptibility to rheumatoid arthritis

    PubMed Central

    van der Horst-Bru..., I E; Hazes, J; Schreuder, G; Radstake, T; Barrera, P; van de Putte, L B A; Mustamu, D; van Schaardenburg, D; Breedveld, F; de Vries, R R P

    1998-01-01

    OBJECTIVE—It has recently been observed that non-inherited maternal DR4 antigens (NIMAs) of DR4 negative rheumatoid arthritis (RA) patients were increased compared with non-inherited paternal DR4 antigens (NIPAs). The aim of this study was to determine the prevalence of non-inherited DR4 antigens and DRB1 alleles in parents of RA patients. 
METHODS—HLA-DR serology and DRB1 typing was performed in 97 RA patients and their parents. NIMA and NIPA frequencies were compared, stratified according to the presence of DR4 and/or the shared epitope (SE).
RESULTS—In DR4 negative patients, NIMA DR4 was increased compared with NIPA DR4 (OR 3.10, 95% CI 0.76, 12.70). When combined with results from a previous study this increase was significant (OR 3.65, 95% CI 1.29, 10.31). The NIMA effect of SE positive DR4 subtypes in this study (OR 4.73, 95% CI 0.94, 23.8) was stronger than the NIMA effect of combined SE positive DRB1 alleles (OR 2.19 95% CI 0.36, 13.22).
CONCLUSIONS—The association between non-inherited maternal HLA-DR4 alleles and the susceptibility to RA was observed in two independent populations.

 Keywords: rheumatoid arthritis; non-inherited maternal DR4 antigens; HLA; genetics PMID:9924209

  10. The M giant candidates identified in the LAMOST DR1

    NASA Astrophysics Data System (ADS)

    Zhong, Jing

    2015-08-01

    M giants are red-giant-branch (RGB) stars with low surface temperature and high luminosity in the late-phase of stellar evolution. Its luminous nature allows us to use these stars as good tracers to study the outer Galactic halo and distant substructures. A well classified M-giant stars sample has important scientific values for the statistic research. In order to fully utilize the spectral data of LAMOST spectroscopic survey, we perform a discrimination procedure with the spectral index diagram of TiO5 and CaH2+CaH3 to separate M giants from M dwarfs. Using the M giant spectra identified from the LAMOST DR1 with high signal-to-noise ratio, we have successfully assembled a set of M giant templates from M0 to M6. Then, the template-fit algorithm were used to automatically identify and classify M giants from the LAMOST DR1. In addition, we calculated the heliocentric radial velocity of all M giants by using the cross-correlation method with the template spectrum in a zero-velocity rest frame. Using the relationship between the absolute infrared magnitude MJ and our classified spectroscopic subtype, we derived the spectroscopic distance of M giants, with uncertainties of about 40%. Finally, we present a spectroscopic catalog of 8639 M giants including stellar parameters like photometry, proper motion, radial velocity, distance, spectral type and so on. In particular, the large sample of M giants is carried out for the first time. We will further use this sample to study the sub-structures and tidal stream in the Galactic Anti-Center.

  11. Introducing Dr. Varga and Some of His Ideas for Probability in the Junior School

    ERIC Educational Resources Information Center

    Sherwood, Philip

    1978-01-01

    Dr. Varga's description of the beginning of the Hungarian Project (primary mathematics) is recorded along with two examples of assignments to generate exploration and discussion involving probability. (MN)

  12. Characteristics of dr1790 disruptant and its functional analysis in Deinococcus radiodurans

    PubMed Central

    Cheng, Jianhui; Wang, Hu; Xu, Xin; Wang, Liangyan; Tian, Bing; Hua, Yuejin

    2015-01-01

    Deinococcus radiodurans (DR) is an extremophile that is well known for its resistance to radiation, oxidants and desiccation. The gene dr1790 of D. radiodurans was predicted to encode a yellow-related protein. The primary objective of the present study was to characterize the biological function of the DR1790 protein, which is a member of the ancient yellow/major royal jelly (MRJ) protein family, in prokaryotes. Fluorescence labeling demonstrated that the yellow-related protein encoded by dr1790 is a membrane protein. The deletion of the dr1790 gene decreased the cell growth rate and sensitivity to hydrogen peroxide and radiation and increased the membrane permeability of D. radiodurans. Transcript profiling by microarray and RT-PCR analyses of the dr1790 deletion mutant suggested that some genes that are involved in protein secretion and transport were strongly suppressed, while other genes that are involved in protein quality control, such as chaperones and proteases, were induced. In addition, the expression of genes with predicted functions that are involved in antioxidant systems, electron transport, and energy metabolism was significantly altered through the disruption of dr1790. Moreover, the results of proteomic analyses using 2-DE and MS also demonstrated that DR1790 contributed to D. radiodurans survival. Taken together, these results indicate that the DR1790 protein from the ancient yellow protein family plays a pleiotropic role in the survival of prokaryotic cells and contributes to the extraordinary resistance of D. radiodurans against oxidative and radiation stresses. PMID:26273280

  13. Safety evaluation for packaging for 1720-DR sodium-filled tank

    SciTech Connect

    Mercado, M.S.

    1996-03-09

    Preparations are under way to sell the sodium stored in the 1720-DR tank in the 1720-DR building. This will require that the tank, as well as the 1720-DR facility, be moved to the 300 Area, so that the sodium may be melted and transferred into a railroad tanker car. Because the sodium is a hazardous material and is being shipped in a nonspecification packaging, a safety evaluation for packaging (SEP) is required. This SEP approves the sodium-filled tank for a single shipment from the 105-DR area to the 300 Area.

  14. Weak association between HLA-DR4 and rheumatoid arthritis in Chilean patients.

    PubMed Central

    Massardo, L; Jacobelli, S; Rodríguez, L; Rivero, S; González, A; Marchetti, R

    1990-01-01

    Evidence has suggested a genetic link between the HLA-DR4 phenotype and rheumatoid arthritis (RA), particularly in its seropositive form. Such an association varies among different ethnic groups and remains controversial for seronegative patients. Data obtained for a group of 64 Chilean patients with RA (46 seropositive, 18 seronegative), as defined by the 1987 criteria of the American Rheumatism Association, and for 76 controls are reported here. The prevalence of HLA-DR4 and DR9 was significantly increased in the group of patients considered as a whole. The prevalence of HLA-DR4 was not significantly higher, however, when seronegative and seropositive patients were separately compared with controls. Also, it did not correlate with the severity of the disease within each subgroup of patients. On the other hand, HLA-DR9 showed a highly significant difference, not previously described, only for the seropositive patients in comparison with controls. The prevalence of DQ specificities showed no relevant differences among the groups. The HLA-DR4 serotype, therefore, is a weak marker for RA and does not differentiate any subgroup of patients in the Chilean group studied. This new finding, indicating an association between RA and the DR9 antigen, may be explained by the suggestion that susceptibility epitopes are shared among different DR molecules. This hypothesis might also account for the variation in the association of DR4 with RA. PMID:2344208

  15. Inhibition of peptide binding to DR molecules by a leupeptin-induced invariant chain fragment.

    PubMed

    Demotz, S; Danieli, C; Wallny, H J; Majdic, O

    1994-08-01

    Loading of peptides onto DR molecules was studied by characterizing precursors of the mature peptide-DR complexes expressed at the surface of B cells. Since invariant chain (Ii) prevents binding of peptides by DR molecules, it was speculated that analysis of complexes between DR heterodimers and proteolytic fragments of Ii offers the possibility to examine how DR molecules and peptides assemble. Using a procedure combining a two-step affinity chromatography and gel filtration, we isolated from leupeptin-treated B cells complexes between DR molecules and N-terminal Ii fragments previously called "leupeptin-induced polypeptides" (LIP; Blum and Cresswell, 1988, Proc. natn. Acad. Sci. U.S.A. 85, 3975-3979). It was observed that the most prominent LIP fragment has a relative molecular mass (M(r)) of 16 kDa. In addition, we show that this polypeptide species does not bear N-linked glycans, indicating that this fragment does not extend beyond residue 129 of Ii. Similarly to DR alpha beta heterodimers associated with the full length 33 and 35 kDa Ii forms, DR alpha beta heterodimers associated with LIP fragments are unstable in sodium dodecyl sulfate (SDS) at ambient temperature, whereas mature DR alpha beta heterodimers are resistant to dissociation with SDS. These results are indirect evidence that LIP-DR complexes are devoid of bound peptides. This possibility was supported by showing that LIP-DR complexes fail to bind a radioiodinated tetanus toxin peptide (125I-p2), while DR molecules, which are spontaneously released from complexes with LIP fragments, bind the labeled peptide. These results demonstrate that association with LIP fragments is sufficient to prevent binding of peptides by DR molecules. This notion was further documented by showing that binding of 125I-p2 on DR heterodimers is inhibited by preparations of LIP fragment. By contrast, a soluble recombinant fragment corresponding to the extracytoplasmic region of Ii did not block 125I-p2 binding. The results

  16. Characteristics of dr1790 disruptant and its functional analysis in Deinococcus radiodurans.

    PubMed

    Cheng, Jianhui; Wang, Hu; Xu, Xin; Wang, Liangyan; Tian, Bing; Hua, Yuejin

    2015-06-01

    Deinococcus radiodurans (DR) is an extremophile that is well known for its resistance to radiation, oxidants and desiccation. The gene dr1790 of D. radiodurans was predicted to encode a yellow-related protein. The primary objective of the present study was to characterize the biological function of the DR1790 protein, which is a member of the ancient yellow/major royal jelly (MRJ) protein family, in prokaryotes. Fluorescence labeling demonstrated that the yellow-related protein encoded by dr1790 is a membrane protein. The deletion of the dr1790 gene decreased the cell growth rate and sensitivity to hydrogen peroxide and radiation and increased the membrane permeability of D. radiodurans. Transcript profiling by microarray and RT-PCR analyses of the dr1790 deletion mutant suggested that some genes that are involved in protein secretion and transport were strongly suppressed, while other genes that are involved in protein quality control, such as chaperones and proteases, were induced. In addition, the expression of genes with predicted functions that are involved in antioxidant systems, electron transport, and energy metabolism was significantly altered through the disruption of dr1790. Moreover, the results of proteomic analyses using 2-DE and MS also demonstrated that DR1790 contributed to D. radiodurans survival. Taken together, these results indicate that the DR1790 protein from the ancient yellow protein family plays a pleiotropic role in the survival of prokaryotic cells and contributes to the extraordinary resistance of D. radiodurans against oxidative and radiation stresses. PMID:26273280

  17. Expression and Mutational Analysis of DinB-Like Protein DR0053 in Deinococcus radiodurans

    PubMed Central

    Appukuttan, Deepti; Seo, Ho Seong; Jeong, Sunwook; Im, Sunghun; Joe, Minho; Song, Dusup; Choi, Jungjoon; Lim, Sangyong

    2015-01-01

    In order to understand the mechanism governing radiation resistance in Deinococcus radiodurans, current efforts are aimed at identifying potential candidates from a large repertoire of unique Deinococcal genes and protein families. DR0053 belongs to the DinB/YfiT protein family, which is an over-represented protein family in D. radiodurans. We observed that dr0053 transcript levels were highly induced in response to gamma radiation (γ-radiation) and mitomycin C (MMC) exposure depending on PprI, RecA and the DrtR/S two-component signal transduction system. Protein profiles demonstrated that DR0053 is a highly induced protein in cultures exposed to 10 kGy γ-radiation. We were able to determine the transcriptional start site of dr0053, which was induced upon irradiation, and to assign the 133-bp promoter region of dr0053 as essential for radiation responsiveness through primer extension and promoter deletion analyses. A dr0053 mutant strain displayed sensitivity to γ-radiation and MMC exposure, but not hydrogen peroxide, suggesting that DR0053 helps cells recover from DNA damage. Bioinformatic analyses revealed that DR0053 is similar to the Bacillus subtilis protein YjoA, which is a substrate of bacterial protein-tyrosine kinases. Taken together, the DNA damage-inducible (din) gene dr0053 may be regulated at the transcriptional and post-translational levels. PMID:25706748

  18. A good start in life: breast-feeding in hospital.

    PubMed

    de Boer, A S; Darnton-Hill, I

    1994-01-01

    The World Health Organization (WHO) and UNICEF introduced the Baby- Friendly Hospital Initiative in 1992 to foster breast feeding in hospitals. The balanced composition of breast milk fulfills the 4-6 month old infant's nutrient requirements. Colostrum is rich in antibodies and immunoglobulins, which protect the newborn against infection. As economic development progresses, more mothers use infant formulas while fewer mothers breast feed. Between 1960 and 1985 in Japan, the proportion of mothers breast feeding 1-2 month old infants fell from 68% to 50%. Between 1975 and 1968 in Western Samoa, it fell from 69% to 48% in urban areas and 78% to 59% in rural areas. Hospital practices that discourage breast feeding include separation of mother and newborn, prelacteal feedings, and free samples of infant formula. These practices occur even in areas, such as the Western Pacific Region, where most mothers deliver at home. Hospital baby-friendly criteria include a written breast-feeding policy, training of all health care staff in skills needed to implement this policy, informing all pregnant women about the benefits and management of breast feeding, assisting mothers to begin breast feeding within 30 minutes of delivery, demonstrating to mothers how to breast feed and to maintain lactation, no prelacteal feeds, newborn rooming-in with mother, promoting breast feeding on demand, no artificial teats or pacifiers, and breast-feeding support groups. The Western Pacific Region supports the Baby-Friendly Hospital Initiative. Between March 1991 and March 1993, the number of baby-friendly hospitals in the Philippines rose from 4 to 103. Dr. Jose Fabella Memorial Hospital in Manila is a model baby-friendly hospital for other hospitals in the region. It does not release mothers until milk flow has been established. By late 1992, 21 Chinese hospitals were baby-friendly. The WHO Western Pacific Region distributes information about breast feeding and the Initiative and provides breast

  19. Influence of Granulocyte-Macrophage Colony-Stimulating Factor or Influenza Vaccination on HLA-DR, Infection and Delirium Days in Immunosuppressed Surgical Patients: Double Blind, Randomised Controlled Trial

    PubMed Central

    Lachmann, Gunnar; Renius, Markus; von Haefen, Clarissa; Wernecke, Klaus-Dieter; Bahra, Marcus; Schiemann, Alexander; Paupers, Marco; Meisel, Christian

    2015-01-01

    Purpose Surgical patients are at high risk for developing infectious complications and postoperative delirium. Prolonged infections and delirium result in worse outcome. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and influenza vaccination are known to increase HLA-DR on monocytes and improve immune reactivity. This study aimed to investigate whether GM-CSF or vaccination reverses monocyte deactivation. Secondary aims were whether it decreases infection and delirium days after esophageal or pancreatic resection over time. Methods In this prospective, randomized, placebo-controlled, double-blind, double dummy trial setting on an interdisciplinary ICU of a university hospital 61 patients with immunosuppression (monocytic HLA-DR [mHLA-DR] <10,000 monoclonal antibodies [mAb] per cell) on the first day after esophageal or pancreatic resection were treated with either GM-CSF (250 μg/m2/d), influenza vaccination (Mutagrip 0.5 ml/d) or placebo for a maximum of 3 consecutive days if mHLA-DR remained below 10,000 mAb per cell. HLA-DR on monocytes was measured daily until day 5 after surgery. Infections and delirium were followed up for 9 days after surgery. Primary outcome was HLA-DR on monocytes, and secondary outcomes were duration of infection and delirium. Results mHLA-DR was significantly increased compared to placebo (p < 0.001) and influenza vaccination (p < 0.001) on the second postoperative day. Compared with placebo, GM-CSF-treated patients revealed shorter duration of infection (p < 0.001); the duration of delirium was increased after vaccination (p = 0.003). Conclusion Treatment with GM-CSF in patients with postoperative immune suppression was safe and effective in restoring monocytic immune competence. Furthermore, therapy with GM-CSF reduced duration of infection in immune compromised patients. However, influenza vaccination increased duration of delirium after major surgery. Trial Registration www.controlled-trials.com ISRCTN27114642 PMID

  20. Hospital diversification strategy.

    PubMed

    Eastaugh, Steven R

    2014-01-01

    To determine the impact of health system restructuring on the levels of hospital diversification and operating ratio this article analyzed 94 teaching hospitals and 94 community hospitals during the period 2008-2013. The 47 teaching hospitals are matched with 47 other teaching hospitals experiencing the same financial market position in 2008, but with different levels of preference for risk and diversification in their strategic plan. Covariates in the analysis included levels of hospital competition and the degree of local government planning (for example, highly regulated in New York, in contrast to Texas). Moreover, 47 nonteaching community hospitals are matched with 47 other community hospitals in 2008, having varying manager preferences for service-line diversification and risk. Diversification and operating ratio are modeled in a two-stage least squares (TSLS) framework as jointly dependent. Institutional diversification is found to yield better financial position, and the better operating profits provide the firm the wherewithal to diversify. Some services are in a growth phase, like bariatric weight-loss surgery and sleep disorder clinics. Hospital managers' preferences for risk/return potential were considered. An institution life cycle hypothesis is advanced to explain hospital behavior: boom and bust, diversification, and divestiture, occasionally leading to closure or merger. PMID:25223156

  1. Star Formation in the DR21 Region (A)

    NASA Technical Reports Server (NTRS)

    2004-01-01

    [figure removed for brevity, see original site] Annotated mosaic

    Hidden behind a shroud of dust in the constellation Cygnus is a stellar nursery called DR21, which is giving birth to some of the most massive stars in our galaxy. Visible light images reveal no trace of this interstellar cauldron because of heavy dust obscuration. In fact, visible light is attenuated in DR21 by a factor of more than 10,000,000,000,000,000,000,000,000,000,000,000,000,000 (ten thousand trillion heptillion).

    New images from NASA's Spitzer Space Telescope allow us to peek behind the cosmic veil and pinpoint one of the most massive natal stars yet seen in our Milky Way galaxy. The never-before-seen star is 100,000 times as bright as the Sun. Also revealed for the first time is a powerful outflow of hot gas emanating from this star and bursting through a giant molecular cloud.

    The colorful image (top panel) is a large-scale composite mosaic assembled from data collected at a variety of different wavelengths. Views at visible wavelengths appear blue, near-infrared light is depicted as green, and mid-infrared data from the InfraRed Array Camera (IRAC) aboard NASA's Spitzer Space Telescope is portrayed as red. The result is a contrast between structures seen in visible light (blue) and those observed in the infrared (yellow and red). A quick glance shows that most of the action in this image is revealed to the unique eyes of Spitzer. The image covers an area about two times that of a full moon.

    Each of the constituent images is shown below the large mosaic. The Digital Sky Survey (DSS) image (lower left) provides a familiar view of deep space, with stars scattered around a dark field. The reddish hue is from gas heated by foreground stars in this region. This fluorescence fades away in the near-infrared Two-Micron All-Sky Survey (2MASS) image (lower center), but other features start to appear through the obscuring clouds of dust, now increasingly transparent. Many more

  2. [WHO AFFECTS THE PATIENT, DR. GOOGLE OR THE DOCTOR?].

    PubMed

    Mishali, Moshe; Avrech, Tova

    2015-09-01

    In the last decade the World Wide Web has become one of the prime sources for medical data searches. The abundance of information and emphasis on consumer communication, which are the main characteristics of the new generation of the web named "Web 2.0", enable users to engage and educate others by sharing and collaborating knowledge. It also enables them to receive medical information based on the experience of other patients, while the duration of the traditional physician's visit has shortened. However, using Web 2.0 for health collaboration has drawbacks as well: When alternative ways of "knowing" replace objective medical facts, there is danger of misinformation and truth "flattening". This article examines the distribution of medical misinformation online: Its characteristics, the nature of the messages presented online and the means that might help protect users and patients from it. The authors hold positions in the Israeli Dairy Board (IDB): Dr. Averch manages the health field on the IDB, and the findings in this article are based on research that she is leading as part of this position, and Dr. Mishali is a trained psychologist, and acts as a strategic consultant for IDB in the field of coping with the opposition to milk and its products. In this article it is initially shown how the characteristics of information distribution in general help spreading medical misinformation online: The decline of doctors' authority as sole providers of medical information, disillusionment and suspicion towards science and the notion of expertise, and the emergence of new ways to evaluate information, based on community ties. The nature of this pseudo-medical information will then be discussed, including the range of the phenomenon and the probability of users to be affected by it. Furthermore, we will raise specific tactics in which anti-establishment messages are portrayed; examples will be given of the use of emotion evoking content in the anti-establishment messages

  3. Measuring Hospital Productivity

    PubMed Central

    Ruchlin, Hirsch S.; Leveson, Irving

    1974-01-01

    This study presents a comprehensive method for quantifying hospital output and estimating hospital productivity. A number of less comprehensive productivity measures that can be quantified from data available from regional third-party payers and from the American Hospital Association are also developed and evaluated as proxies for the comprehensive measure, which is based on local area data. Methods are discussed for estimating the necessary variables on a regional or national level. PMID:4461703

  4. A Failed Utopia in Marcela Del Río's "Proceso a Faubritten"

    ERIC Educational Resources Information Center

    Manickam, Samuel

    2014-01-01

    In Marcela del Río's science fiction novel "Proceso a Faubritten," utopia comes in the form of eternal life for all of humanity, thanks to Dr. Alexander Faubritten's "Bomba L." This polyphonic work includes diaries by Faubritten and his Mexican lover, María Corona. In my analysis of these two diaries, I will show how…

  5. Dr. Bernard Langer - inductee into the Canadian Medical Hall of Fame.

    PubMed

    Greig, Paul D; Rotstein, Ori D

    2015-04-01

    Dr. Bernard Langer's induction into the Canadian Medical Hall of Fame acknowledges his profound effect on medicine and surgery in Canada and an impact that has been truly international. In this brief biography, we highlight the major accomplishments that have made Dr. Langer a pre-eminent leader, innovator, teacher and exemplary surgeon. PMID:25799243

  6. Dr. Bernard Langer — inductee into the Canadian Medical Hall of Fame

    PubMed Central

    Greig, Paul D.; Rotstein, Ori D.

    2015-01-01

    Summary Dr. Bernard Langer’s induction into the Canadian Medical Hall of Fame acknowledges his profound effect on medicine and surgery in Canada and an impact that has been truly international. In this brief biography, we highlight the major accomplishments that have made Dr. Langer a pre-eminent leader, innovator, teacher and exemplary surgeon. PMID:25799243

  7. Evolutionary relationship between human major histocompatibility complex HLA-DR haplotypes

    SciTech Connect

    Svensson, A.C.; Setterblad, N.; Pihlgren, U.; Rask, L.; Andersson, G.

    1996-09-01

    HLA-DR haplotypes of the human major histocompatibility complex are organized in five different groups. They can be identified based on the serological specificity expressed by the polymorphic DRB1 locus and by the presence of a characteristic set of DRB genes. The nucleotide sequences of introns 4 and 5 of the two DRB genes (DRB1*01 and DRB6*01) from a DR1 haplotype and the three DRB genes (DRB1*15, DRB6*15, and DRB5*15), from a DR51 haplotype were determined. This study identified endogenous retroviral long terminal repeat elements (ERV9 LTR) located at identical positions in intron 5 of the DRB1 genes in both the DR1 and DR51 haplotypes. Phylogenetic analyses revealed a close evolutionary relationship between these two haplotypes. The DRB5 gene, unique for the DR51 haplotype, may have been lost by a recent gene deletion event creating the DR1 haplotype. A model for the evolution of the human DR haplotypes involving separate duplication and contraction events is presented. 55 refs., 5 figs., 2 tabs.

  8. 78 FR 7438 - Prospective Grant of Exclusive License: Development of Human Monoclonal Antibodies Against DR4

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... Human Monoclonal Antibodies Against DR4 AGENCY: National Institutes of Health, Public Health Service... Monoclonal Antibodies Against DR4'' (HHS Ref. No. E-158-2010/0) to Customized Biosciences, Inc., which is... relates to the development of two human monoclonal antibodies (mAbs) that bind to death receptor 4...

  9. HLA class II genes polymorphism in DR4 giant cell arteritis patients.

    PubMed

    Bignon, J D; Ferec, C; Barrier, J; Pennec, Y; Verlingue, C; Cheneau, M L; Lucas, V; Muller, J Y; Saleun, J P

    1988-11-01

    We have previously reported a significant increase of HLA-DR4 antigen frequency in giant cell arteritis (GCA). This finding suggested an important role of immunogenetic factors in this syndrome. Recent data suggest that inherited susceptibility to several autoimmune diseases was associated with specific DR4 associated DQ beta alleles. DNAs from 27 DR4 positive patients with GCA were digested with Taq I and Bam HI, analysed on 0.7% agarose gel and hybridized with DR beta, DQ alpha and DQ beta probes. DR beta hybridization produced no variant detectable within DR4. DQ beta probe confirmed two clusters among DR4 associated DQW3 alleles: DQW 3.1 (Bam HI 360 Kb) and DQw 3.2 (Taq I 1.9 Kb and Bam HI 11 Kb). Among our 27 DR4 positive patients, 34% were DQW 3.1 and 66% were DQW 3.2. These frequencies are the same as those observed in healthy controls. PMID:2906182

  10. GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis.

    PubMed

    Kurita, S; Mott, J L; Almada, L L; Bronk, S F; Werneburg, N W; Sun, S-Y; Roberts, L R; Fernandez-Zapico, M E; Gores, G J

    2010-08-26

    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis through its cognate receptors death receptor 4 (DR4) and death receptor 5 (DR5), preferentially in malignant cells. However, many malignant cells remain resistant to TRAIL cytotoxicity by poorly characterized mechanisms. Here, using cholangiocarcinoma cells, as a model for TRAIL resistance, we identified a role for the oncogenic Hedgehog (Hh)-GLI pathway in the regulation of TRAIL cytotoxicity. Blockade of Hh using pharmacological and genetic tools sensitizes the cells to TRAIL cytotoxicity. Restoration of apoptosis sensitivity coincided with upregulation of DR4 expression, while expression of other death effector proteins remained unaltered. Knockdown of DR4 mimics Hh-mediated resistance to TRAIL cytotoxicity. Hh regulates the expression of DR4 by modulating the activity of its promoter. Luciferase, chromatin immunoprecipitation and expression assays show that the transcription factor GLI3 binds to the DR4 promoter and Hh requires an intact GLI3-repression activity to silence DR4 expression. Finally, small interfering RNA (siRNA)-targeted knockdown of GLI3, but not GLI1 or GLI2, restores DR4 expression and TRAIL sensitivity, indicating that the Hh effect is exclusively mediated by this transcription factor. In conclusion, these data provide evidence of a regulatory mechanism, which modulates TRAIL signaling in cancer cells and suggest new therapeutic approaches for TRAIL-resistant neoplasms. PMID:20562908

  11. GLI3-dependent repression of DR4 mediates hedgehog antagonism of TRAIL-induced apoptosis

    PubMed Central

    Kurita, S; Mott, JL; Almada, LL; Bronk, SF; Werneburg, NW; Sun, S-Y; Roberts, LR; Fernandez-Zapico, ME; Gores, GJ

    2010-01-01

    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis through its cognate receptors death receptor 4 (DR4) and death receptor 5 (DR5), preferentially in malignant cells. However, many malignant cells remain resistant to TRAIL cytotoxicity by poorly characterized mechanisms. Here, using cholangiocarcinoma cells, as a model for TRAIL resistance, we identified a role for the oncogenic Hedgehog (Hh)-GLI pathway in the regulation of TRAIL cytotoxicity. Blockade of Hh using pharmacological and genetic tools sensitizes the cells to TRAIL cytotoxicity. Restoration of apoptosis sensitivity coincided with upregulation of DR4 expression, while expression of other death effector proteins remained unaltered. Knockdown of DR4 mimics Hh-mediated resistance to TRAIL cytotoxicity. Hh regulates the expression of DR4 by modulating the activity of its promoter. Luciferase, chromatin immunoprecipitation and expression assays show that the transcription factor GLI3 binds to the DR4 promoter and Hh requires an intact GLI3-repression activity to silence DR4 expression. Finally, small interfering RNA (siRNA)-targeted knockdown of GLI3, but not GLI1 or GLI2, restores DR4 expression and TRAIL sensitivity, indicating that the Hh effect is exclusively mediated by this transcription factor. In conclusion, these data provide evidence of a regulatory mechanism, which modulates TRAIL signaling in cancer cells and suggest new therapeutic approaches for TRAIL-resistant neoplasms. PMID:20562908

  12. Vikrant Sahasrabuddhe, MBBS, MPH, DrPH | Division of Cancer Prevention

    Cancer.gov

    Dr. Vikrant Sahasrabuddhe received his medical degree from the University of Pune in India, his master's and doctorate degrees in public health from the University of Alabama at Birmingham, and completed fellowship training in epidemiology at the Johns Hopkins University Bloomberg School of Public Health and at the National Cancer Institute. Before joining NCI in 2015, Dr. |

  13. The Scholarship of Dr. Asa G. Hilliard, III: Implications for Black Principal Leadership

    ERIC Educational Resources Information Center

    Tillman, Linda C.

    2008-01-01

    For over 40 years the scholarship of Dr. Asa G. Hilliard has impacted the fields of educational psychology, testing and measurement, teacher education, and African and African American history. Dr. Hilliard was also concerned about school leadership, and much of his work is closely aligned with current discussions about school reform and…

  14. Central line infections - hospitals

    MedlinePlus

    ... infection; CVC - infection; Central venous device - infection; Infection control - central line infection; Nosocomial infection - central line infection; Hospital acquired infection - central line infection; Patient safety - central ...

  15. A study of the occurrence of HLA DR2 in 124 narcoleptics: clinical aspects.

    PubMed

    Roth, B; Nevsímalová, S; Sonka, K; Docekal, P; Schulz, H; Geisler, P; Pollmächer, T; Andreas-Zietz, A; Keller, E; Scholz, S

    1988-01-01

    The authors examined HLA antigens in 124 narcoleptics. In addition to narcolepsy, 122 patients suffered also from cataplexy. The two patients without cataplexy suffered also from sleep paralysis and hypnagogic hallucinations. These two symptoms were also present in many of the other patients. HLA group DR2 was found in 120 patients including all six symptomatic cases. In four patients HLA DR2 was not present. Two of these were fully pronounced narcolepsy-cataplexy cases whereas the two other did not suffer from cataplexy. Since several other cases with negative DR2 have already been published it is necessary to admit the existence of DR2-negative narcolepsy, albeit very rare. Among 5 patients with isolated sleep paralysis HLA DR2 was present in one familial and 1 sporadic case. The authors further discuss some aspects of the classification of narcolepsies in the light of recent HLA studies as well as their delimitation from idiopathic hypersomnia. PMID:2459761

  16. 105-DR Large Sodium Fire Facility decontamination, sampling, and analysis plan

    SciTech Connect

    Knaus, Z.C.

    1995-06-12

    This is the decontamination, sampling, and analysis plan for the closure activities at the 105-DR Large Sodium Fire Facility at Hanford Reservation. This document supports the 105-DR Large Sodium Fire Facility Closure Plan, DOE-RL-90-25. The 105-DR LSFF, which operated from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility in the 100-D Area of the Hanford Site. The LSFF was established to investigate fire fighting and safety associated with alkali metal fires in the liquid metal fast breeder reactor facilities. The decontamination, sampling, and analysis plan identifies the decontamination procedures, sampling locations, any special handling requirements, quality control samples, required chemical analysis, and data validation needed to meet the requirements of the 105-DR Large Sodium Fire Facility Closure Plan in compliance with the Resource Conservation and Recovery Act.

  17. Reflections of a soon-to-be former DR

    SciTech Connect

    Larson, N.I.

    1997-12-31

    SRP, formerly known as Salt River Project, is actually a combination of two organizations, The Salt River Valley Water Users` Association (the {open_quotes}Association{close_quotes}), and the Salt River Project Agricultural Improvement and Power District (the {open_quotes}District{close_quotes}). The Association was incorporated under the laws of the Territory of Arizona in 1903, and is one of the first projects authorized under the Federal Reclamation Act of 1902. The District was formed in 1937 as a political subdivision of the State of Arizona, and is responsible for the construction, operation and maintenance of the Electric System and the irrigation and water supply system. Generation and sale of electrical power and energy represent a significant portion of the District`s investment and revenues. SRP has a total capability of over 5000 MW from hydroelectric, thermal and purchased sources, Of this, almost 2400 MW is provided by Title IV, Phase II affected units. Phase II units must comply with the SO{sub 2} allowance program starting in the year 2000. SRP operates four facilities having Title IV units. The implementation of Title IV requires the selection of a Designated Representative (DR) to represent the utility and all utilities in the participation plants the utility may operate, to be responsible for reporting emissions of sulfur dioxide and oxides of nitrogen to the United States Environmental Protection Agency on a quarterly and annual basis and certify to the accuracy and completeness of the information.

  18. Dr. Monaco Examines Lab-on a-Chip

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Dr. Lisa Monaco, Marshall Space Flight Center's (MSFC's) project scientist for the Lab-on-a-Chip Applications Development (LOCAD) program, examines a lab on a chip. The small dots are actually ports where fluids and chemicals can be mixed or samples can be collected for testing. Tiny channels, only clearly visible under a microscope, form pathways between the ports. Many chemical and biological processes, previously conducted on large pieces of laboratory equipment, can now be performed on these small glass or plastic plates. Monaco and other researchers at MSFC in Huntsville, Alabama, are customizing the chips to be used for many space applications, such as monitoring microbes inside spacecraft and detecting life on other planets. The portable, handheld Lab-on-a Chip Application Development Portable Test System (LOCAD-PTS) made its debut flight aboard Discovery during the STS-116 mission launched December 9, 2006. The system allowed crew members to monitor their environment for problematic contaminants such as yeast, mold, and even E.coli, and salmonella. Once LOCAD-PTS reached the International Space Station (ISS), the Marshall team continued to manage the experiment, monitoring the study from a console in the Payload Operations Center at MSFC. The results of these studies will help NASA researchers refine the technology for future Moon and Mars missions. (NASA/MSFC/D.Stoffer)

  19. Kinematics and activity of M dwarfs in LAMOST DR1

    NASA Astrophysics Data System (ADS)

    Yi, Zhen-Ping; Luo, A.-Li; Zhao, Jing-Kun; Song, Yi-Han; Pan, Jing-Chang; Zhao, Yong-Heng; Zhang, Yong

    2015-06-01

    We report on the first investigation into kinematics and chromospheric activity of M dwarfs from the Guo Shou Jing Telescope (also called the Large Sky Area Multi-Object Fiber Spectroscopic Telescope - LAMOST) data release one (DR1). The sample comprises 71 304 M dwarfs. Their fundamental parameters such as spectral types, radial velocities, important molecular band indices and magnetic activities are measured. Their distances are determined by a spectroscopic parallax relation. Space motion (U, V, W) and Galactocentric cylindrical coordinates (R, θ, Z) for the M dwarfs are also computed. We examine velocity dispersion as a function of height from the Galactic plane and find that all three components of velocity dispersion increase with height as measured with respect to the Galactic plane. The investigation into chromospheric activities along the height from the Galactic plane confirms that M dwarfs closer to the Galactic plane are more likely to be active. We take a pure kinematical approach to select thin disk stars and thick disk stars from our sample, then to investigate the differences in properties between these two populations. Our analysis is in excellent agreement with previous studies and leads to a better understanding of the structure of the Galactic disk. Supported by the National Natural Science Foundation of China.

  20. "Treating Lungs": The Scientific Contributions of Dr. Theodor Kolobow.

    PubMed

    Trahanas, John M; Kolobow, Mary Anne; Hardy, Mark A; Berra, Lorenzo; Zapol, Warren M; Bartlett, Robert H

    2016-01-01

    We are fortunate to live in an age in which biomedical technology has provided us with unprecedented ability to supplant the functions of organs and support the physiologic processes of the human body. Ingenious doctors, physiologists, and engineers helped create these advances with new and innovative ideas. One of these pioneers was Dr. Theodor Kolobow. He is best known for one of his earliest inventions, the spiral coil membrane lung. His contributions to medical innovation, however, are diverse, as he also contributed to advances in hemodialysis, improvements in extracorporeal life support technology/circuit components, and through his laboratory experiments helped shape our current understanding of cardiopulmonary pathophysiology. In retrospect, much of Kolobow's work was unified by the theme of preventing iatrogenic lung injury caused by mechanical ventilation. This tenet became more obvious as his later studies progressed to developing techniques and devices intended to limit ventilator pressures, and prevent bacterial colonization of the lungs. Although he formally retired from his research endeavors in 2009, the impact of his contributions remains prominent in our everyday use of techniques and equipment that he either originated or helped to develop. PMID:26720733

  1. Identification of the HLA-DM/HLA-DR interface.

    PubMed

    Davies, Matthew N; Lamikanra, Abigail; Sansom, Clare E; Flower, Darren R; Moss, David S; Travers, Paul J

    2008-02-01

    Human leukocyte antigen (HLA)-DM is a critical participant in antigen presentation that catalyzes the dissociation of the Class II-associated Invariant chain-derived Peptide (CLIP) from the major histocompatibility complex (MHC) Class II molecules. There is competition amongst peptides for access to an MHC Class II groove and it has been hypothesised that DM functions as a 'peptide editor' that catalyzes the replacement of one peptide for another within the groove. It is established that the DM catalyst interacts directly with the MHC Class II but the precise location of the interface is unknown. Here, we combine previously described mutational data with molecular docking and energy minimisation simulations to identify a putative interaction site of >4000A2 which agrees with known point mutational data for both the DR and DM molecule. The docked structure is validated by comparison with experimental data and previously determined properties of protein-protein interfaces. A possible dissociation mechanism is suggested by the presence of an acidic cluster near the N terminus of the bound peptide. PMID:17870168

  2. Three moving groups detected in the LAMOST DR1 archive

    SciTech Connect

    Zhao, J. K.; Zhao, G.; Chen, Y. Q.; Tan, K. F.; Oswalt, T. D.; Zhang, Y. E-mail: oswaltt1@erau.edu

    2014-05-20

    We analyze the kinematics of thick disk and halo stars observed by the Large Sky Area Multi-Object Fiber Spectroscopic Telescope. We have constructed a sample of 7993 F, G, and K nearby main-sequence stars (d < 2 kpc) with estimates of position (x, y, z) and space velocity (U, V, W) based on color and proper motion from the Sloan Digital Sky Survey DR9 catalog. Three 'phase-space overdensities' are identified in (V, √(U{sup 2}+2V{sup 2})) with significance levels of σ > 3. Two of them (the Hyades-Pleiades stream and the Arcturus-AF06 stream) have been identified previously. We also find evidence for a new stream (centered at V ∼ –180 km s{sup –1}) in the halo. The formation mechanisms of these three streams are analyzed. Our results support the hypothesis that the Arcturus-AF06 stream and the new stream originated from the debris of a disrupted satellite, while the Hyades-Pleiades stream has a dynamical origin.

  3. [Life and work of Dr. Jovan Jovanović Zmaj].

    PubMed

    Lesić, Aleksandar; Bumbasirević, Marko; Zizić-Borjanović, Slavica

    2006-10-01

    The year of 2004 was the 100th anniversary of death of the poet and physician Dr. Jovan Jovanović Zmaj. Jovan Jovanović Zmaj was born in 1833 in Novi Sad, and died in 1904 in Sremska Kamenica J.J. Zmaj himself studied law and worked in the Novi Sad magistrate court. It was not until he turned 30 that he began practicing medicine. He developed as a poet as early as during his studies. He remained loyal to the vocations of physician and poet throughout his life. He wrote over 5000 poems, ranging from those for children through those for adults and those with which he addressed the rulers satirically. He was a founder of a number of magazines (Javor, Neven, Komarac, Danica). At that time of Romanticism, the work of J.J. Zmaj also had a national character. However, he succeeded in achieving something more: he introduced a literary genre till then unknown in Serb literature--literature for children. Through his genre he promoted not only Serbian language but also hygiene, by which he played a significant health care role, similar to that played by his friend Milan Jovanović Batut, only from a different aspect. He also used to draw, and his drawing of the emblem of the Serbian Literary Association has remained on the cover of every book published by it until these days. PMID:18172968

  4. 2015 AMCA Memorial Lecture Honoree: Dr. Richard Floyd Darsie, Jr.

    PubMed

    Day, Jonathan F

    2015-12-01

    Richard Floyd Darsie, Jr. (1915-2014) is the 2015 American Mosquito Control Association Memorial Lecture Honoree. He was one of the greatest mosquito taxonomists of the 20th century and died peacefully on April 10, 2014, in Grove City, PA, at the age of 99 after a professional career that spanned eight decades. Dick's broad areas of interest and training made him a versatile scientist, teacher, and researcher. His intense interest in adult and immature mosquito morphology and taxonomy, as well as mosquito distribution and bionomics, started early in his career at two early academic postings: Franklin and Marshall College (1949-54) and the University of Delaware (1954-62). Dick would take his mosquito interests with him to postings and research projects around the world: Nepal, the Philippines, Atlanta, El Salvador, Guatemala, Fort Collins, South Carolina, Argentina, and Florida. His travels and studies would make him an international expert on mosquito taxonomy. Dick's legacy lives on in the hundreds of students from across the globe who learned mosquito identification skills from this world-renowned mosquito taxonomist. All will proudly profess that, "I learned mosquito identification from Dr. Darsie." And that is all that is needed to prove one's credentials in the field, learning the art from the best there is. PMID:26675466

  5. Dr William Wilson Ingram (1888-1982): doctor-soldier, physician and Antarctic expeditioner.

    PubMed

    Pearn, J H

    2011-09-01

    Dr William Wilson Ingram (1888-1982), a Scottish-born physician, contributed significantly to the health and heritage of Australia, his adopted land. Born on Speyside and educated in Aberdeen, he was a doctor-soldier in two World Wars and decorated with the Military Cross. Ingram was a Foundation Fellow (1938) of the Royal Australasian College of Physicians and established one of the first specialist diabetic clinics in Australia, in Sydney in 1928. As an arachnologist, he published clinical descriptions of both surviving and fatal cases of envenomation by the Sydney funnel web spider, Atrax robustus. He founded the Kolling Institute of Medical Research at the Royal North Shore Hospital in Sydney where for two generations he was a leader in both undergraduate and postgraduate medical education. The international significance of his life's work relates to his service as the medical officer and biologist on the two British, Australian and New Zealand Antarctic Research Expeditions (BANZARE) of 1929-1931, for which service he was awarded the Polar Medal and subsequent Clasp. Those expeditions secured, for the British Crown, what was to become the Australian Antarctic Territory, ceded to Australia by a British Order in Council of 24 August 1936. Sir Douglas Mawson, polar expeditioner and the leader of BANZARE, described Ingram as 'an ideal medical officer', one who in addition to his clinical skills and judgement, manifested courage and 'physical endurance and a full measure of camaraderie'. Ingram has no published obituary or biography. This précis records some details of his extraordinary life. PMID:21949929

  6. Mrs. Chandrasekhar addresses the media in TRW Media Hospitality Tent

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Mrs. Lalitha Chandrasekhar (right), wife of the late Indian- American Nobel Laureate Subrahmanyan Chandrasekhar, addresses the media and other invited guests in the TRW Media Hospitality Tent at the NASA Press Site at KSC as Dr. Alan Bunner, Science Program Director, Structure and Evolution of the Universe, Office of Space Science, NASA Headquarters, Washington, D.C., looks on. The name 'Chandra,' a shortened version of her husband's name which he preferred among friends and colleagues, was chosen in a contest to rename the Advanced X-ray Astrophysics Facility. 'Chandra' also means 'Moon' or 'luminous' in Sanskrit. The observatory is scheduled to be launched aboard Columbia on Space Shuttle mission STS-93.

  7. Hospitality Occupations. Curriculum Guide.

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento. Bureau of Homemaking Education.

    This curriculum guide on the hospitality occupations was developed to help secondary and postsecondary home economics teachers prepare individuals for entry-level jobs in the hospitality industry. The content is in seven sections. The first section presents organizational charts of a medium-size hotel, food and beverage division, housekeeping and…

  8. Library Services in Hospitals.

    ERIC Educational Resources Information Center

    Department of Health and Social Security, London (England).

    The memorandum gives guidance to the provision and organization of library services at hospitals both for staff and for patients. It also draws attention to the assistance available from outside sources towards the development and maintenance of these services so hospital authorities may make the most effective use of the available facilities.…

  9. Hospitality, Tourism, and Recreation.

    ERIC Educational Resources Information Center

    Novachek, James

    The Northern Arizona Hospitality Education Program is an exemplary three-year project designed to help students, mainly Indian, obtain job skills and attitudes necessary for successful employment in the hospitality industry. Nine high schools from Apache, Coconino, and Navajo Counties participated in the project. Objectives included providing an…

  10. Handbook on Hospital Television.

    ERIC Educational Resources Information Center

    Prynne, T. A.

    Designed for both hospital personnel interested in television and audiovisual personnel entering the medical field, this handbook is a verbal and pictorial survey of what is being done with TV within the medical profession. After an introduction which answers technical questions about medical TV posed during the American Hospital Association's…

  11. Mental hospitals in India.

    PubMed

    Krishnamurthy, K; Venugopal, D; Alimchandani, A K

    2000-04-01

    This review traces the history of the mental hospital movement, initially on the world stage, and later in India, in relation to advances in psychiatric care. Mental hospitals have played a significant role in the evolution of psychiatry to its present statusThe earliest hospital in India were established during the British colonial rule. They served as a means to isolate mentally ill persons from the societal mainstream and provide treatments that were in vogue at the time. Following India's independence, there has been a trend towards establishing general hospital psychiatry units and deinstitutionalization, while at the same time improving conditions in the existing mental hospitals.Since 1947, a series of workshops of superintendents was conducted to review the prevailing situations in mental hospitals and to propose recommendations to improve the same. Implementation of the Mental Health Act, 1987, and grovernmental focus upon mental hospital reform have paved way for a more specific and futuristic role for mental hospitals in planning psychiatric services for the new millenium, especially for severe mental illnesses. PMID:21407925

  12. [Music in the hospital].

    PubMed

    Bouteloup, Philippe

    2010-01-01

    Occasional events, regular workshops, concerts, shows, artists in residence, cultural outings...Hospital does not necessarily have to be a place of silence and sadness. But this situation has not always been so straightforward as on the face of it, nothing is more incompatible with a hospital environment than music, which, by definition, is festive and noisy. PMID:20684389

  13. Hospitality services generate revenue.

    PubMed

    Bizouati, S

    1993-01-01

    An increasing number of hospitals are undertaking external revenue-generating activities to supplement their shrinking budgets. Written at the request of Leadership, this article outlines an example of a successful catering service -- a money-generating business that more Canadian hospitals could profitably consider. PMID:10127850

  14. Hospitality Services Reference Book.

    ERIC Educational Resources Information Center

    Texas Tech Univ., Lubbock. Home Economics Curriculum Center.

    This reference book provides information needed by employees in hospitality services occupations. It includes 29 chapters that cover the following topics: the hospitality services industry; professional ethics; organization and management structures; safety practices and emergency procedures; technology; property maintenance and repair; purchasing…

  15. Hospitality Services. Curriculum Guide.

    ERIC Educational Resources Information Center

    Texas Tech Univ., Lubbock. Home Economics Curriculum Center.

    This guide, which was developed as part of Texas' home economics education program, is intended to assist teachers of a hospitality services course focusing on the food and lodging segments of the hospitality and tourism industry. The first 40% of the approximately 600-page guide consists of strategies for teaching each of 29 essential…

  16. A clinical examination of the efficacy of preparation of Dr Michaels® (also branded as Soratinex®) products in the treatment of psoriasis.

    PubMed

    Hercogovấ, J; Fioranelli, M; Gianfaldoni, S; Chokoeva, A A; Tchernev, G; Wollina, U; Tirant, M; Novotny, F; Roccia, M G; Maximov, G K; França, K; Lotti, T

    2016-01-01

    Psoriasis is a chronic inflammatory disease with negative impacts both physically and psychologically. It is a common disorder affecting 2-3% of the total world population, in some cases causing changes to the nail and joints as well as skin lesions. The cutaneous manifestations of psoriasis can vary in morphology and severity and therapy should be tailored accordingly. The aim of the study was to investigate the efficacy of Dr Michaels® (Soratinex®) product line in the treatment of psoriatic patients with different age and disease severity. A total number of 270 patients with verified psoriasis, aged 9-60 years old participated in the studies, including 128 children: 23 girls and 105 boys, (all of them selected from the Department of Dermato-allergology of the Russian Pediatric Hospital Clinic, Moscow, and of the 4th Department of Dermatology of the 52nd Moscow City Hospital Clinic). The patients were separated into 3 groups according to the severity of the disease (based on the PASI-index). All the patients have been treated with Dr Michaels® (Soratinex®) products twice daily, as three different forms were available for application: a cleansing gel, an ointment and a conditioner. The severity of the disease and the efficacy of the treatment have been defined with the evaluation of the PASI index of each patient. The obtained results were recorded in a graphic form showing the changes of the PASI-index on days 3, 7, 14, and 21 counted from the start of the trial. Clinical remission was achieved in 147 patients, a significant improvement in 73, partial improvement in 32, while no effect was seen in 12 patients and deterioration in 6. This open trial demonstrated the clinical efficacy of topical application of Dr Michaels® (Soratinex®) preparation. We observed clinical remissions of psoriasis in adults and in children. PMID:27498653

  17. Hospital efficiency and debt.

    PubMed

    Bernet, Patrick Michael; Rosko, Michael D; Valdmanis, Vivian G

    2008-01-01

    U.S. Hospitals rely heavily on debt financing to fund major capital investments. Hospital efficiency is at least partly determined by the amount and quality of plant and equipment it uses. As such, a hospital's access to debt and credit rating may be related to its efficiency. This study explores this relationship using a broad sample of hospitals and associated bond issuance histories. Employing stochastic frontier analysis (SFA), we measure cost inefficiency to gauge the impact of debt issuance and debt rating. We find that hospitals with recent bond issues were less inefficient. Although we do not find a perfectly linear relationship between debt rating and inefficiency, we have evidence that hints at such a relation. Finally, we find an increase in inefficiency in the years following bond issues, consistent with the possibility of a debt death spiral. PMID:21110482

  18. [Hospital medicine in Chile].

    PubMed

    Eymin, Gonzalo; Jaffer, Amir K

    2013-03-01

    After 15 years of development of Hospital Medicine in Chile, there are several benefits of this discipline. Among others, a reduction in the length of hospital stay, readmissions, costs, and improved medical teaching of students, residents and fellows have been observed. However, in South América there are only isolated groups dedicated to Hospital Medicine in Chile, Argentina and Brazil, with a rather slow growth. The unjustified fear of competition from sub specialists, and the fee for service system of payment in our environment may be important factors to understand this phenomenon. The aging of the population makes imperative to improve the safety of our patients and to optimize processes and resources within the hospital, to avoid squandering healthcare resources. The following is a detailed and evidence-based article, on how hospital medicine might benefit both the public and prívate healthcare systems in Chile. PMID:23900327

  19. Hospitality as an Environmental Metaphor.

    ERIC Educational Resources Information Center

    Horwood, Bert

    1991-01-01

    Compares stewardship and hospitality as they relate to the biosphere. Traces the origin of the word "hospitality," discusses cultural traditions of hospitality, and applies the concept of hospitality to the natural world. Considers forms of symbiosis in nature: commensals, mutualism, and parasitism. Hospitality promotes respect, humility, and…

  20. Morphology and Absolute Magnitudes of the SDSS DR7 QSOs

    NASA Astrophysics Data System (ADS)

    Coelho, B.; Andrei, A. H.; Antón, S.

    2014-10-01

    The ESA mission Gaia will furnish a complete census of the Milky Way, delivering astrometrics, dynamics, and astrophysics information for 1 billion stars. Operating in all-sky repeated survey mode, Gaia will also provide measurements of extra-galactic objects. Among the later there will be at least 500,000 QSOs that will be used to build the reference frame upon which the several independent observations will be combined and interpreted. Not all the QSOs are equally suited to fulfill this role of fundamental, fiducial grid-points. Brightness, morphology, and variability define the astrometric error budget for each object. We made use of 3 morphological parameters based on the PSF sharpness, circularity and gaussianity, which enable us to distinguish the "real point-like" QSOs. These parameters are being explored on the spectroscopically certified QSOs of the SDSS DR7, to compare the performance against other morphology classification schemes, as well as to derive properties of the host galaxy. We present a new method, based on the Gaia quasar database, to derive absolute magnitudes, on the SDSS filters domain. The method can be extrapolated all over the optical window, including the Gaia filters. We discuss colors derived from SDSS apparent magnitudes and colors based on absolute magnitudes that we obtained tanking into account corrections for dust extinction, either intergalactic or from the QSO host, and for the Lyman α forest. In the future we want to further discuss properties of the host galaxies, comparing for e.g. the obtained morphological classification with the color, the apparent and absolute magnitudes, and the redshift distributions.

  1. [Dr Lorenzo Dojmi di Delupis- the "Leopard" from Vis].

    PubMed

    Jamnicki Dojmi, Mirko

    2011-01-01

    Dr Lorenzo Dojmi di Delupis (1845-1927) was a descendant of a respectful aristocratic family from Vis. His father was Peter Dojmi di Delupis (1809-1886), an attorney, a moderate pro-Italian autonomist, and a mayor of Vis, and his mother was Margherita Siminati. As soon as he graduated from the Medical University of Graz in 1870, he joined the Ottoman army as a physician for a two-year journey in which he reached as far as Baghdad and Basra. He left notes about this dramatic, juvenile adventure in his diaries. In 1878, he married a Viennese girl Maria Neidl and brought her home to Vis, where he got a position of municipal doctor. He had an extraordinary diagnosing acuity, great sympathy for patients, and was always willing to help, which is why he was adored by all the people of Vis, whether they agreed with his autonomist ideas or not, and soon became "the father of Vis". He was the first to warn of leprosy in Dalmatia, when he diagnosed two cases in Vis. Beside medicine and politics, he was also a passionate botanist. He was the first to seed palms in Vis and to grow a palm nursery with his agronomist son Peter Dojmi, for the whole of Dalmatia. He also tried breeding ostriches and growing Mexican coffee. He funded a small meteorological station in Vis, and planned to open a health resort with professor Schröter from Vienna. Even though Lorenzo Dojmi di Delupis held the great Italian culture very dear, his vocation as a physician and humanist inclination never let him burn with the fervour of a political extremist. Thanks to his psychophysical stability, he overcame numerous difficulties in life and retained faith in people. All these traits evoke Prince Salina, the leading character of the renowned novel Il gattopardo (The Leopard) by Giuseppe Tomasi di Lampedusa, which is why the author has so entitled this article "The Gattopardo of Vis". PMID:22292541

  2. Mechanism by which HLA-DR4 Regulates Sex-bias of Arthritis in humanized mice

    PubMed Central

    Behrens, Marshall; Trejo, Theodore; Luthra, Harvinder; Griffiths, Marie; David, Chella S; Taneja, Veena

    2010-01-01

    HLA class II allele DRB1*0401 is associated with predisposition to Rheumatoid Arthritis in humans as well as collagen-induced arthritis in mice. Predominantly females develop arthritis in humans and DR4 transgenic mice; however the mechanism of sex-bias is still unknown. We have investigated the molecular basis by which DR4 is associated with sex-bias of arthritis. Here we show that differential antigen-specific immune mechanisms in DR4 male and female mice lead to increased susceptibility in female mice. B cells are hyperactive and present DR-restricted peptides robustly in females compared to males. Antigen-specific response showed that females produced B cell modulating cytokines like IL-13 while males produced IFNγ. Male transgenic mice have higher number of T and B regulatory cells. An exogenous supply of 17β estradiol in male mice led to enhanced expression of DR4 and antigen-specific response to DR4-restricted peptides. On the other hand, castration increased the incidence of arthritis. We propose that sex-bias in arthritis involves B cells and presentation of antigen by HLA-DR4 leading to activation of autoreactive cells and autoantibodies production in females, while regulatory B cells in males protect them from pathogenesis. The transgenic mice expressing RA susceptible haplotype simulate human RA and may be valuable to study gender differences observed in patients. PMID:20061120

  3. Then & Now: Research Pays Off for All Americans / Dr. Virginia Apgar: Keeping Score at Baby's First Cry | NIH ...

    MedlinePlus

    ... of Physicians and Surgeons. “Every baby born in America benefits from Dr. Apgar's pioneering work to identify ... devoted to newborn care. "Every baby born in America benefits from Dr. Apgar's pioneering work to identify ...

  4. [Yesterdays and happenings at hospitals of Tehuacán, Puebla, México].

    PubMed

    Fajardo-Ortiz, Guillermo

    2004-01-01

    The history of the hospital of Tehuacán, the second city importance in Puebla State, began in 1744, when the Hospital de San Juan de Dios (Hospital of St. John) was founded; in 1820, it was converted into the Municipal of Civil Hospital. The medical establishement continues to provide services to the poor to this day annual also covers health public workers of services for the municipality. The Hospital de la Cruz Roja Mexicana (The Mexican Red Cross Hospital) was created in 1934 provide medical services for accident victims: The hospital services of the Mexican Institute of Social Security (IMSS) began in 1953; an earthquake destroyed the building in 1973, and a new hospital was inaugurated in 1979; at present, it readers services to 98,000 persons. The Sanatorio del Sagrado Corazón (Sacred Heart Sanatorium) is a private religious institution founded at the beginning of the second half the 20th century. In 1996, the Hospital General (General Hospital) began to provide services, takes care of the poor of the geographical region, and is financed with federal funds. The Instituto de Seguridad y Servicios Sociales para Trabajadores del Estado (Institute of Securtiy and Social Services for the Workers of the State, ISSSTE) has a small hospital with 10 beds, it was founded in 1995. PMID:15087055

  5. Lymphocyte responses to DR1/4 restricted peptides in rheumatoid arthritis.

    PubMed Central

    Skinner, M A; Watson, L; Geursen, A; Tan, P L

    1994-01-01

    OBJECTIVE--To determine whether analog and unrelated DR1/4 binding peptides alter DR1/4 restricted responses of peripheral blood lymphocytes (PBL) from patients with rheumatoid arthritis (RA). METHODS--PBL from 25 patients with RA and 12 healthy controls were cultured with DR1/4 restricted peptides of the influenza haemagglutinin, amino acids 307-319 (HA) and matrix proteins, amino acids 17-29 (IM). Responses were determined by 3H-thymidine uptake proliferation assays and limiting dilution analysis. Competitor peptides were analogs HA-R312 and HA-K313 differing from HA by one amino acid at the 312 or 313 position respectively or unrelated peptides which bind to DR1/4. RESULTS--The responses of eight patients with RA to the two stimulatory influenza peptides did not differ significantly from controls and this was confirmed by the frequency estimate of T cells in PBL which responded to HA (mean frequency: 1 in 9.0 x 10(4), n = 5, in DR1/4+ RA patients, 1 in 7.6 x 10(4), n = 5, in DR1/4+ healthy controls). DR1/4 binding analogs of the HA peptide inhibited HA specific peptide responses of PBL from patients with RA and controls. Inhibition was also detected with unrelated peptides which bind to DR1/4 but to which the individual did not respond. CONCLUSION--Similar responses to two DR1/4 restricted peptides were observed in patients with RA and controls. Both antigen analog- and unrelated peptide-major histocompatibility complexes (MHC) can result in the inhibition of antigen specific responses in multi-clonal human lymphocyte populations. However, an analog peptide may be stimulatory in some individuals. These results provide some initial data for the development of a rational approach to MHC-specific immunomodulation in rheumatoid arthritis. Images PMID:8154934

  6. Is rheumatoid arthritis in Indians associated with HLA antigens sharing a DR beta 1 epitope?

    PubMed Central

    Ollier, W E; Stephens, C; Awad, J; Carthy, D; Gupta, A; Perry, D; Jawad, A; Festenstein, H

    1991-01-01

    HLA class II antigens were identified in a group of 44 patients with rheumatoid arthritis (RA) originating largely from the north or northeast of the Indian subcontinent and resident now in east London. Compared with 67 locally typed east London Asian controls, the prevalence of three HLA-DR antigens was raised in the patients: DR1 18.2% v 6.0% chi 2 = 3.99, DR4 20.5% v 11.9% chi 2 = 1.48, and DRw10 27.3% v 8.9% chi 2 = 6.56. These differences were also found when the patients with RA were compared with a larger control group of 110 northern Indians: DR1 18.2% v 7.2% chi 2 = 4.02, DR4 20.5% v 7.2% chi 2 = 5.56, and DRw10 27.3% v 8.1% chi 2 = 9.7. Twenty five (57%) of the patients expressed at least one of these antigens. All patients were also characterised for HLA-Dw types by mixed lymphocyte culture typing. The prevalence of the HLA-DR4 associated Dw types in the patients was: Dw4 2.3%, Dw10 0%, Dw14 11.4%, and Dw15 6.8%. The DR beta 1 chains of DR1 and DRw10 together with the Dw types of DR4 other than Dw10 share amino acid residues in a region of the third hypervariable region considered to be critical in antigen presentation. It is concluded that RA in Indians is associated with these HLA antigens, and data from this study support the hypothesis of a cross reactive epitope common to HLA specificities associated with RA. PMID:1710441

  7. Dose reduction using prior image constrained compressed sensing (DR-PICCS)

    NASA Astrophysics Data System (ADS)

    Tang, Jie; Thériault Lauzier, Pascal; Chen, Guang-Hong

    2011-03-01

    A technique for dose reduction using prior image constrained compressed sensing (DR-PICCS) in computed tomography (CT) is proposed in this work. In DR-PICCS, a standard FBP reconstructed image is forward projected to get a fully sampled projection data set. Meanwhile, it is low-pass filtered and used as the prior image in the PICCS reconstruction framework. Next, the prior image and the forward projection data are used together by the PICCS algorithm to obtain a low noise DR-PICCS reconstruction, which maintains the spatial resolution of the original FBP images. The spatial resolution of DR-PICCS was studied using a Catphan phantom by MTF measurement. The noise reduction factor, CT number change and noise texture were studied using human subject data consisting of 20 CT colonography exams performed under an IRB-approved protocol. In each human subject study, six ROIs (two soft tissue, two colonic air columns, and two subcutaneous fat) were selected for the CT number and noise measurements study. Skewness and kurtosis were used as figures of merit to indicate the noise texture. A Bland-Altman analysis was performed to study the accuracy of the CT number. The results showed that, compared with FBP reconstructions, the MTF curve shows very little change in DR-PICCS reconstructions, spatial resolution loss is less than 0.1 lp/cm, and the noise standard deviation can be reduced by a factor of 3 with DR-PICCS. The CT numbers in FBP and DR-PICCS reconstructions agree well, which indicates that DR-PICCS does not change CT numbers. The noise textures indicators measured from DR-PICCS images are in a similar range as FBP images.

  8. The extraordinary career of Professor Dr. Simon van Creveld.

    PubMed

    Stoelinga, Paul J W; Berdon, Walter E; Cohen, M Michael

    2014-11-01

    Simon van Creveld received both the MD and PhD degrees and had a multifaceted medical and scientific education at many hospitals and research institutes in the Netherlands, Germany, and the UK. He and his wife were the first to develop insulin for the Netherlands. His major interests were in hemophilia and hemorrhagic disorders, which accounted for 87 of his publications. In 1934, van Creveld demonstrated that a dispersed protein fraction obtained from serum could reduce the clotting time of hemophilic blood. His interest in glycogen storage disease resulted in van Creveld-von Gierke disease for which van Creveld contributed four published articles. The Ellis-van Creveld syndrome, also known as chondroectodermal dysplasia, was published in 1940 and became well known to medical geneticists. During the Nazi occupation of the Netherlands, van Creveld's professorship was taken away from him because he was Jewish. His visits to hospitals of concentration camps to treat babies and give pediatric advice while wearing a Jewish Yellow Star and interacting with SS Commandants in charge, and then leaving can only be described as amazing. After the war, his professorship was returned, and in the same year as his retirement, he established a large Hemophila Treatment and Research Center now known as the Van Creveld Clinic, which celebrated its 40th anniversary in 2005. PMID:25269937

  9. The enigmatic figure of Dr Henry Maudsley (1835-1918).

    PubMed

    Pantelidou, Maria; Demetriades, Andreas K

    2014-08-01

    In spite of his contribution to psychiatry in 19th century Britain, Henry Maudsley remains a mysterious figure, a man mostly known for his donation to the London County Council for the building of the Maudsley Hospital and for The Maudsley Annual Lecture created in honour of his benevolence. Besides Sir Aubrey Lewis' article in 1951 and Michael Collie's attempt in 1988 to construct a biographical study on Maudsley, there does not seem to be any current endeavour to tell the story of his life, whereas Trevor Turner's contribution to the 2004 Oxford Dictionary of National Biography gives a somewhat scathing but unattributed account of Maudsley's personality. This essay attempts to explore his contributions to the Medico-Psychological Association (MPA), the current Royal College of Psychiatrists, his editorship of the Journal of Mental Health (currently named the British Journal of Psychiatry), his literary contributions and his vision for a psychiatric hospital. This essay is an attempt to demystify his figure and to explore some of the rumours and criticisms surrounding his name and the reasons why so little has been written about him. It is also a venture to unravel his complex personality and his intricate philosophy. PMID:24944050

  10. Combined use of RFLP and PCR-ASO typing for HLA-DR-Dw and DQw typing.

    PubMed

    Bignon, J D; Bidwell, J L

    1991-01-01

    Due to some limitations of restriction fragment length polymorphism (RFLP) analysis in HLA-DR-DQ typing, we present a combined use of RFLP and polymerase chain reaction (PCR)-allele-specific oligonucleotide (ASO) typing. This scheme consists in selectively amplifying the few RFLP ill-defined genes (DR1/DR'Br' and DR4-Dw subsets) using PCR with allele specific primers to avoid cross-hybridization. PMID:1676910

  11. Philanthropy and hospital financing.

    PubMed Central

    Smith, D G; Clement, J P; Wheeler, J R

    1995-01-01

    OBJECTIVE. This study explores the relationships among donations to not-for-profit hospitals, the returns provided by these hospitals, and fund-raising efforts. It tests a model of hospital behavior and addresses an earlier debate regarding the supply price of donations. DATA SOURCES. The main data source is the California Office of Statewide Health Planning data tapes of hospital financial disclosure reports for fiscal years 1980/1981 through 1986/1987. Complete data were available for 160 hospitals. STUDY DESIGN. Three structural equations (donations, returns, and fund-raising) are estimated as a system using a fixed-effects, pooled cross-section, time-series least squares regression. PRINCIPAL FINDINGS. Estimation results reveal the expected positive relation between donations and returns. The reverse relation between returns and donations is insignificant. The estimated effect of fund-raising on donations is insignificantly different from zero, and the effect of donations on fund-raising is negative. Fund-raising and returns are negatively associated with one another. CONCLUSION. The empirical results presented here suggest a positive donations-returns relations and are consistent with a positive supply price for donations. Hospitals appear to view a trade-off between providing returns and soliciting donations, but donors do not respond equally to these two activities. Attempts to increase free cash flow through expansion of community returns or fund-raising activity, at least in the short run, are not likely to be highly successful financing strategies for many hospitals. PMID:8537223

  12. Hospitals' Internal Accountability

    PubMed Central

    Kraetschmer, Nancy; Jass, Janak; Woodman, Cheryl; Koo, Irene; Kromm, Seija K.; Deber, Raisa B.

    2014-01-01

    This study aimed to enhance understanding of the dimensions of accountability captured and not captured in acute care hospitals in Ontario, Canada. Based on an Ontario-wide survey and follow-up interviews with three acute care hospitals in the Greater Toronto Area, we found that the two dominant dimensions of hospital accountability being reported are financial and quality performance. These two dimensions drove both internal and external reporting. Hospitals' internal reports typically included performance measures that were required or mandated in external reports. Although respondents saw reporting as a valuable mechanism for hospitals and the health system to monitor and track progress against desired outcomes, multiple challenges with current reporting requirements were communicated, including the following: 58% of survey respondents indicated that performance-reporting resources were insufficient; manual data capture and performance reporting were prevalent, with the majority of hospitals lacking sophisticated tools or technology to effectively capture, analyze and report performance data; hospitals tended to focus on those processes and outcomes with high measurability; and 53% of respondents indicated that valuable cross-system accountability, performance measures or both were not captured by current reporting requirements. PMID:25305387

  13. Hospitals' internal accountability.

    PubMed

    Kraetschmer, Nancy; Jass, Janak; Woodman, Cheryl; Koo, Irene; Kromm, Seija K; Deber, Raisa B

    2014-09-01

    This study aimed to enhance understanding of the dimensions of accountability captured and not captured in acute care hospitals in Ontario, Canada. Based on an Ontario-wide survey and follow-up interviews with three acute care hospitals in the Greater Toronto Area, we found that the two dominant dimensions of hospital accountability being reported are financial and quality performance. These two dimensions drove both internal and external reporting. Hospitals' internal reports typically included performance measures that were required or mandated in external reports. Although respondents saw reporting as a valuable mechanism for hospitals and the health system to monitor and track progress against desired outcomes, multiple challenges with current reporting requirements were communicated, including the following: 58% of survey respondents indicated that performance-reporting resources were insufficient; manual data capture and performance reporting were prevalent, with the majority of hospitals lacking sophisticated tools or technology to effectively capture, analyze and report performance data; hospitals tended to focus on those processes and outcomes with high measurability; and 53% of respondents indicated that valuable cross-system accountability, performance measures or both were not captured by current reporting requirements. PMID:25305387

  14. Dr. John Frederick May and the identification of John Wilkes Booth's body.

    PubMed

    Spiegel, A D

    1998-10-01

    Shortly after President Abraham Lincoln's assassin was killed on April 26, 1865, a formal inquest was held to positively identify the body. Dr. John Frederick May, a leading surgeon in the District of Columbia, was summoned to examine the remains. Two years earlier, Dr. May had removed a fibroid tumor from the back of the assassin's neck and an identifiable large ugly scar resulted when the wound inadvertently opened and healed by granulation. Based upon the recognition of the scar made by his scalpel, Dr. May made a positive identification. PMID:9793835

  15. Dr. Ray Gause examines student Skylab experiment ED-52 Web Formation

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Dr. Ray Gause of the NASA-Marshall Space Flight Center (MSFC) places dinner, in the form of a housefly, in the web of Arabella - the prime spider for the ED-52 Web Formation Experiment. Arabella can be delineated near the end of the black pen in Dr. Gause's hand. The experiment is one of 25 student experiments accepted for the Skylab program and will be performed during the Skylab 3 mission. Judy Miles, a 17-year-old high school student from Lexington, Massachusetts, is the student experimenter and Dr. Gause is the NASA student advisor.

  16. Hospitalized Patients and Fungal Infections

    MedlinePlus

    ... but can also be caused by fungi. Hospital construction. Hospital staff do everything they can to prevent ... patients staying at hospitals where there is ongoing construction or renovation. 5 This is thought to be ...

  17. Historical review: First facial pain patient admitted to Massachusetts General Hospital, February 1823 and first case series.

    PubMed

    Keith, David A; Dodson, Thomas B; Kaban, Leonard B

    2013-08-01

    Founded in 1811, the Massachusetts General Hospital recently celebrated its bicentennial. The War of 1812 delayed construction of the building so the first patient actually was admitted to the hospital 10 years later, on September 3, 1821. By 1823, the 60 hospital beds were full. Patient 66 was admitted on February 28, 1823, and his hospital course, as described in the admissions book, was transcribed for the Massachusetts General Hospital bicentennial celebration. That case history is reproduced and a case series of 6 similar patients published in 1828 by Dr John Warren, surgeon-in-chief and a founder of the hospital, is presented. In this report, the authors comment on the diagnosis, treatment, and outcome of these patients in the context of the contemporaneous health care environment and in light of the current knowledge of facial pain disorders. This article was adapted from the authors' commentary for the bicentennial celebration. PMID:23866949

  18. The Hospital for Special Surgery affiliates with Cornell University Medical College and New York Hospital, 1951; Philip D. Wilson retires as Surgeon-in-Chief, 1955.

    PubMed

    Levine, David B

    2009-09-01

    When World War II ended in 1945, the Hospital for Special Surgery (HSS), the oldest orthopedic hospital in the country, was entering its eighth decade. Only 5 years previously, its name was changed from the Hospital for the Ruptured and Crippled (R & C). In 1934, Dr. Philip D. Wilson (1886-1969) had been recruited to fill the office of the fifth Surgeon-in-Chief with a key charge to restore the hospital as the leading orthopedic institution in our country, a role it originally held for over half a century since its founding in 1863. Wilson believed that a close affiliation with a university center having a medical school and hospital, while maintaining independence, was vital to achieve this objective. In 1948, negotiations between representatives of the Board of the New York Society for the Relief of the Ruptured and Crippled and representatives of the Society of the New York Hospital and Cornell Medical Center began and a preliminary written agreement was reached in March, the next year. The affiliation called for construction of a new building to house approximately 170 inpatient beds for orthopedics and arthritis. The land on the East River between 70th and 71st Streets, owned by New York Hospital, was to be given, without monetary exchange, to the Hospital for Special Surgery for construction of its new hospital. Finally, on November 1, 1951, a new non-proximate agreement was ratified. On May 25, 1955, after 43 years at 321 East 42nd Street, the Hospital for Special Surgery moved to its new six million dollar building at 535 East 70th Street where it formally became affiliated with New York Hospital-Cornell Medical Center. Two months later, on July 1, 1955, Philip D. Wilson retired as Surgeon-in-Chief to become the Hospital for Special Surgery's new Director of Research and Surgeon-in-Chief Emeritus. PMID:19506964

  19. Hospital Waste Management in Nonteaching Hospitals of Lucknow City, India

    PubMed Central

    Manar, Manish Kumar; Sahu, Krishna Kumar; Singh, Shivendra Kumar

    2014-01-01

    Objective: To assess hospital waste management in nonteaching hospitals of Lucknow city. Materials and Methods: A cross-sectional, descriptive study was conducted on the staffs of nonteaching hospitals of Lucknow from September 2012 to March 2013. A total of eight hospitals were chosen as the study sample size. Simple random sampling technique was used for the selection of the nonteaching hospitals. A pre-structured and pre-tested interview questionnaire was used to collect necessary information regarding the hospitals and biomedical waste (BMW) management of the hospitals. The general information about the selected hospitals/employees of the hospitals was collected. Results: Mean hospital waste generated in the eight nonteaching hospitals of Lucknow was 0.56 kg/bed/day. About 50.5% of the hospitals did not have BMW department and colored dustbins. In 37.5% of the hospitals, there were no BMW records and segregation at source. Incinerator was used only by hospital A for treatment of BMW. Hospital G and hospital H had no facilities for BMW treatment. Conclusion: There is a need for appropriate training of staffs, strict implementation of rules, and continuous surveillance of the hospitals of Lucknow to improve the BMW management and handling practices. PMID:25657950

  20. Gamification of Clinical Routine: The Dr. Fill Approach.

    PubMed

    Bukowski, Mark; Kühn, Martin; Zhao, Xiaoqing; Bettermann, Ralf; Jonas, Stephan

    2016-01-01

    Gamification is used in clinical context in the health care education. Furthermore, it has shown great promises to improve the performance of the health care staff in their daily routine. In this work we focus on the medication sorting task, which is performed manually in hospitals. This task is very error prone and needs to be performed daily. Nevertheless, errors in the medication are crucial and lead to serious complications. In this work we present a real world gamification approach of the medication sorting task in a patient's daily pill organizer. The player of the game needs to sort the correct medication into the correct dispenser slots and is rewarded or punished in real time. At the end of the game, a score is given and the user can register in a leaderboard. PMID:27332203

  1. Hospital financing in Norway.

    PubMed

    Carlsen, F

    1994-05-01

    The Norwegian block grant reform of 1980 replaced state reimbursements to hospitals by block grants allocated to counties according to objective criteria. The reform was accompanied by a general decentralization of budget authority to local level. The reform aimed to promote primary care, equalize the supply of health care across regions and give counties incentives to improve hospital efficiency. A decade later, the reform was reversed. The government has imposed restrictions which reduce the budget discretion of the counties and part of the block grant has been made dependent on the performance of the hospitals in the counties. The government has also issued a 'waiting-list guarantee' which states that patients who suffer from a serious disease are entitled to medical treatment within six months. This paper provides an overview of hospital financing in Norway during the last two decades and discusses why the block grant system did not fulfil the expectations of its architects. PMID:10136059

  2. Surgery, Hospitals, and Medications

    MedlinePlus

    Patient Education Sheet Sjögren’s, Surgery, Hospitals, and Medications The SSF thanks Lynn Petruzzi, RN, MSN, for this Patient Education Sheet. Educate your healthcare givers! • Tell your surgeon, ...

  3. Critical Access Hospitals (CAH)

    MedlinePlus

    ... CAH Conditions of Participation . What are the location requirements for CAH status? Critical Access Hospitals must be ... clinic that does not meet the CAH distance requirements? As of January 1, 2008, all CAHs, including ...

  4. Understanding your hospital bill

    MedlinePlus

    ... to know whether your hospital charged a fair price. There are some web sites you can use ... zip code to find an average or estimated price in your area. www.healthcarebluebook.com www.fairhealth. ...

  5. Practice Hospital Bed Safety

    MedlinePlus

    ... Bed? Todd says that there is no standard definition for hospital beds, a fact that consumers shopping ... in retail stores that don’t meet the definition of medical devices under the law, but which ...

  6. Hospital free cash flow.

    PubMed

    Kauer, R T; Silvers, J B

    1991-01-01

    Hospital managers may find it difficult to admit their investments have been suboptimal, but such investments often lead to poor returns and less future cash. Inappropriate use of free cash flow produces large transaction costs of exit. The relative efficiency of investor-owned and tax-exempt hospitals in the product market for hospital services is examined as the free cash flow theory is used to explore capital-market conditions of hospitals. Hypotheses concerning the current competitive conditions in the industry are set forth, and the implications of free cash flow for risk, capital-market efficiency, and the cost of capital to tax-exempt institution is compared to capital-market norms. PMID:1743965

  7. [Ryazan hospital--80 years].

    PubMed

    Klimov, A S; Gromov, M F

    2012-02-01

    In December 2011 marked 80 years of the founding of the Ryazan garrison hospital, originally housed in two buildings: "Redut housed"--a monument of architecture of the XVIII century and the former almshouses room "for the maimed in the war", was built in 1884 now Ryazan garrison hospital (from 2010--Branch No 6 FSI "in 1586 the district military hospital in the Western Military District", the Defense Ministry of Russia)--a multi-field medical preventive institution on the basis of which soldiers, military retirees, family members and military retirees from Ryazan, Moscow, Tambov regions are treated. Every year more than 7 thousand patients get treatment here. During the counterterrorism operations in Chechnya over 800 wounded were brought to the hospital from the battle area. PMID:22558855

  8. ["Working together" at hospital?].

    PubMed

    Divay, Sophie

    2015-02-01

    Working well together at hospital depends on several factors, on the level of a team as well as that of the ministry in charge of health. How can we encourage and promote cooperation between caregivers? If the hospital is the reflection of society as a whole, an analysis of the functioning of this universe provides a better understanding of the challenges and the missions of each player for the benefit of the patient. PMID:26144821

  9. Fast tracking hospital construction.

    PubMed

    Quirk, Andrew

    2013-03-01

    Hospital leaders should consider four factors in determining whether to fast track a hospital construction project: Expectations of project length, quality, and cost. Whether decisions can be made quickly as issues arise. Their own time commitment to the project, as well as that of architects, engineers, construction managers, and others. The extent to which they are willing to share with the design and construction teams how and why decisions are being made. PMID:23513759

  10. Management of Feedyard Hospitals.

    PubMed

    Fox, J T

    2015-11-01

    There are many considerations when managing feedyard hospitals. The type of hospital system must fit the facility design, the type of cattle fed at the feedyard, the crew that is employed by the feedyard, and the protocol established by the veterinarian. Ensuring the animals are well-cared for and have their basic needs met should be the priority of the feedyard personnel and the veterinarian maintaining the veterinarian-client-patient relationship with the feedyard. PMID:26210766

  11. Hospital air is sick.

    PubMed

    Brownson, K

    2000-11-01

    Indoor air quality has deteriorated so much since the 1970s oil shortage and subsequent energy-efficient construction of buildings that people are becoming seriously ill by just breathing the indoor air. This is a problem with all industrial buildings and hospital staff are at particular risk. There are various things that hospital managers from different departments can do to make the air safe for staff and patients to breathe. PMID:11185833

  12. Eye-Eye with Dr. Rachel Bishop | NIH MedlinePlus the Magazine

    MedlinePlus

    ... this page please turn JavaScript on. Feature: Glaucoma Eye-to-Eye with Dr. Rachel Bishop Past Issues / Spring 2015 ... new patient comes in because they scratched their eye while working in the yard, or they think ...

  13. Interview with ARPA-E Acting Director Dr. Cheryl Martin on Platts Energy Week

    SciTech Connect

    Martin, Cheryl; Loveless, Bill

    2014-03-18

    Bill Loveless from Platts Energy Week interviews ARPA-E Acting Director, Dr. Cheryl Martin, about the many transformational energy technologies on display at ARPA-E's 5th annual Energy Innovation Summit.

  14. Ask Dr. Sue--Updates: Infectious Diseases, SIDS, HIV/AIDS.

    ERIC Educational Resources Information Center

    Aronson, Susan S.

    1995-01-01

    Describes new concerns about infectious diseases in childcare settings (tuberculosis, gastrointestinal infections, and lice); sleep position and SIDS; HIV/AIDS issues; and the use of sterilized sand in sand boxes. (DR)

  15. The role of HLA-DR antigens in PPD-stimulated lymphocyte-monocyte interactions.

    PubMed

    Haar, D; Heron, I

    1982-11-01

    Autologous monocytes are required for an optimal lymphocyte proliferative response to purified protein derivate of tuberculin (PPD) in vitro and for a mixed lymphocyte culture induced by alloantigens. In the proliferative response to PPD we found that autologous monocytes could be replaced with HLA-DR-compatible monocytes and partly with HLA-DR semi-identical. In spite of a statistically significant difference between autologous and HLA-DR disparate monocytes in their cooperative capacity with PPD-stimulated lymphocytes, replacement in nearly one third of the cases was possible. These findings were supported by more detailed studies in which increasing numbers of allogenic and autologous monocytes were added to the isolated lymphocytes in the presence of PPD. It is concluded that the serologically defined HLA-DR antigens alone give insufficient information of the restriction elements controlling the PPD-stimulated lymphocyte-monocyte interactions. PMID:6184773

  16. VizieR Online Data Catalog: KODIAQ DR1 (O'Meara+, 2015)

    NASA Astrophysics Data System (ADS)

    O'Meara, J. M.; Lehner, N.; Howk, J. C.; Prochaska, J. X.; Fox, A. J.; Swain, M. A.; Gelino, C. R.; Berriman, G. B.; Tran, H.

    2016-04-01

    As part of the Keck Observatory Database of Ionized Absorption toward Quasars (KODIAQ) survey, we have uniformly processed the HIRES spectra of hundreds of quasars. The HIRES spectrograph is located on the KeckI telescope. In this work, we present the first Data Release (DR1) from the survey. Data taken over the last two decades from the HIRES spectrograph fall into three general categories. The first is the earliest data from 1995 to 1997. The second category spans the years 1997-2004. Finally, the third category covers data from 2004 to the present. The data in DR1 are all drawn from this last category. The KODIAQ DR1 comprises 170 quasars observed in the mosaic configuration of HIRES between 2004 and 2012. Note that one quasar is a lensed system, so the number of individual sightlines is 171. The DR1 sample is summarized in Table2. (1 data file).

  17. New NIH Director Dr. Francis Collins on Medical Research That Benefits Everyone's Health

    MedlinePlus

    ... benefit everyone's health." — NIH Director Dr. Francis Collins Healthcare Reform— We can put science to work to better ... of this? Under the American Recovery and Reinvestment Act, NIH has received $10 billion in stimulus funding, ...

  18. Eye Expert Dr. Emily Chew: 3 Ways to Keep Your Sight

    MedlinePlus

    ... Issues Feature: Vision Eye Expert Dr. Emily Chew: 3 Ways to Keep Your Sight Past Issues / Summer ... a healthy diet. New research shows that omega-3 fatty acids may protect the retina from wear. ...

  19. Onboard photo: Japanese Payload Specialist Dr. Mamoru Mohri at work in Spacelab-J module

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Space Shuttle Endeavour (STS-47) onboard photo of Japanese Payload Specialist Dr. Mamoru Mohri participating in Comparative Measurement of Visual Stability in Earth Cosmic Space experiment to learn more about Space Adaptation Syndrome (SAS).

  20. Description of work for 100-DR-2 Operable Unit Vadose Drilling/test pits

    SciTech Connect

    Naiknimbalkar, N.

    1993-08-01

    This report describes the scope of work for the boreholes/test pits of the 100-DR-2 Operable Unit. Sampling and field activities include: Soil screening; geologic sampling; soil sampling (physical property); analytical sampling and depths; and geophysical logging.

  1. APOLLO 14 DR. WERNHER VON BRAUN WATCHES FROM FIRING ROOM 2

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Dr. Wernher von Braun, the NASA Deputy Associate Administrator for Future Programs, uses binoculars to monitor data on closed- circuit television screens in Firing Room 2 of the Launch Control Center during final Apollo 14 launch preparations today.

  2. ISS Update: Dr. Steve Squyres, NEEMO 16 Aquanaut and Cornell Professor

    NASA Video Gallery

    ISS Update Commentator Pat Ryan interviews Dr. Steve Squyres, NEEMO 16 Aquanaut and Cornell Professor, about simulating a mission to an asteroid underwater. The Aquarius habitat simulates the isola...

  3. Dr. Rachel Bishop's Top Tips for Your Eyes | NIH MedlinePlus the Magazine

    MedlinePlus

    ... this page please turn JavaScript on. Feature: Treating Cataracts Dr. Rachel Bishop's Top Tips for Your Eyes ... as baseballs, wood chips, or debris. Lenses After Cataract Surgery After your eye's natural lens has been ...

  4. Dr. Grant Heikan examines lunar material in sieve from sample container

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Dr. Grant Heikan, Manned Spacecraft Center and a Lunar Sample preliminary Examination Team member, examines lunar material in a sieve from the bulk sample container which was opened in the Biopreparation Laboratory of the Lunar Receiving Laboratory.

  5. Dr Mary Crosse, OBE, MD (1900–1972) and the premature baby

    PubMed Central

    Dunn, P M

    2007-01-01

    On behalf of Birmingham's Department of Public Health, Dr Crosse developed the Sorrento Premature Baby Unit in 1931 and pioneered the modern care of these small newborn infants in Britain. PMID:17337665

  6. Interview with ARPA-E Acting Director Dr. Cheryl Martin on Platts Energy Week

    ScienceCinema

    Martin, Cheryl; Loveless, Bill

    2014-04-11

    Bill Loveless from Platts Energy Week interviews ARPA-E Acting Director, Dr. Cheryl Martin, about the many transformational energy technologies on display at ARPA-E's 5th annual Energy Innovation Summit.

  7. HLA-A, B and DR in Caucasians with transitional cell carcinoma of the bladder.

    PubMed

    Saunders, P H; Anderson, S A; Stogdill, V D; Lamm, D L

    1983-11-01

    When HLA-A, B and DR antigens in Caucasian patients with transitional cell carcinoma of the urinary bladder were compared with controls, no significant alterations in antigen frequencies were found. PMID:6581580

  8. High Blood Cholesterol Q&A Dr. Michael Lauer | NIH MedlinePlus the Magazine

    MedlinePlus

    ... fat from primarily white (energystoring) to primarily brown (energy-burning) forms, thereby correcting the metabolic abnormalities associated with obesity. Evaluating the "local effects" of fat. For example, Dr. Caroline Fox ...

  9. Magnitude and determinants of diabetic retinopathy among persons with diabetes registered at employee health department of a tertiary Eye Hospital of central Saudi Arabia

    PubMed Central

    Khandekar, Rajiv; Al Hassan, Arif; Al Dhibi, Hassan; Al Bahlal, Abdullah; Al-Futais, Muneera

    2015-01-01

    Background: To estimate the magnitude and determinants of diabetic retinopathy (DR) among persons with diabetes registered at the employee health department of King Khaled Eye Specialist Hospital (KKESH). Methods: A retrospective review of medical records was conducted in 2013–14 at KKESH. The case record review extracted demographic, profile of diabetes, diabetic complications, and different blood indices to determine the status of potential risk factors. Ocular profile, especially DR was also noted. Results: Our cohort had 94 staff with diabetes. Eye examination was carried out in 51 (54.8%) of them. The rate of DR was 52% (95% confidence interval (CI) 28–66). Sight-threatening diabetic retinopathy (STDR) (proliferative DR and/or diabetic macular edema) was present in 40% of those examined. Good glycemic control was noted in 42% of participants. Duration of diabetes was associated with DR (P = 0.04). Good glycemic control was negatively associated to DR (odds ratio = 0.2 [95% CI 0.04–0.6]). The coverage of eye screening was 55% only. Laser treatment was given to 80% of STDR cases. The lens opacity and glaucoma rate was 15% and 8.3%, respectively. Conclusions: Low coverage for eye screening and laser treatment to diabetics among the staff of an eye hospital is a matter of concern. The underlying causes of low coverage of screening, digital fundus photography as a screening tool and management should be addressed. PMID:26903721

  10. Recurrent psychiatric hospitalization.

    PubMed Central

    Voineskos, G.; Denault, S.

    1978-01-01

    Undue emphasis has been placed on rising rates of readmission to psychiatric facilities. After a decade of preoccupation with discharge rates, readmission statistics have been singled out in the last 15 years as the key factor for assessing hospital effectiveness. A study of a group of patients at high risk for recurrent hospitalization revealed that these patients were characterized more by features relating to environmental supports than by diagnosis. The operational definition for recurrent hospitalization (five or more admissions during the 2-year period preceding the latest admission) was effective in identifying this group; this is the first reported instance in which the definition has specified a certain number of admissions within a time-limited period. The findings of this study, as well as of an analysis of case histories and consumer opinion, led to the design of a pilot program for persons undergoing recurrent hospitalization. Readmission statistics are useless or misleading as measures of hospital effectiveness and efficiency; what matters is the way the former patients function in the community after discharge. Rather than simply trying to reduce the readmission rate psychiatric facilities should be examining the types of persons who are hospitalized recurrently to develop programs aimed at improving the functioning of these people in the community. PMID:630483

  11. Hospital accreditation in Europe.

    PubMed

    Shaw, C

    1998-01-01

    Health service accreditation systems have explicit standards for organisation against which the participating hospital assesses itself before a structured visit by outside "surveyors". They submit a written report back to the hospital with commendations and recommendations for development prior to a follow-up survey. Accreditation may be awarded for a fixed term or may be with held by an independent assessment Board if the hospital does not meet a defined threshold of standards. In Europe, some government and medical organisations initially distanced themselves from the pilot hospital wide programmes, arguing that they would cost too much and undermine management, or that they were irrelevant to clinical practice. But gradually it became obvious that accreditation worked for hospitals; purchasers and insurers saw its potential for quality and resource management; and professional bodies recognised the links between clinical training, practice and outcome and the environment in which health care is provided. If nothing else, it offered a multi-professional bridge between the existing numerous fragmented systems such as inspecting (statutory safety), visiting (professional training), and monitoring (service contracts). The introduction of accreditation appears to benefit hospitals in many different countries and health systems and provides a vehicle for integrated quality management which is visible to funding agencies, government and the public. Interest is growing within Europe. PMID:10179643

  12. Financing hospital disaster preparedness.

    PubMed

    De Lorenzo, Robert A

    2007-01-01

    Disaster preparedness and response have gained increased attention in the United States as a result of terrorism and disaster threats. However, funding of hospital preparedness, especially surge capacity, has lagged behind other preparedness priorities. Only a small portion of the money allocated for national preparedness is directed toward health care, and hospitals receive very little of that. Under current policy, virtually the entire funding stream for hospital preparedness comes from general tax revenues. Medical payers (e.g., Medicare, Medicaid, and private insurance) directly fund little, if any, of the current bill. Funding options to improve preparedness include increasing the current federal grants allocated to hospitals, using payer fees or a tax to subsidize preparedness, and financing other forms of expansion capability, such as mobile hospitals. Alternatively, the status quo of marginal preparedness can be maintained. In any event, achieving higher levels of preparedness likely will take the combined commitment of the hospital industry, public and private payers, and federal, state, and local governments. Ultimately, the costs of preparedness will be borne by the public in the form of taxes, higher healthcare costs, or through the acceptance of greater risk. PMID:18087914

  13. The function of DrPax1b gene in the embryonic development of zebrafish.

    PubMed

    Liu, Xin; Wang, Hua; Li, Guang; Huang, Hui-Zhe; Wang, Yi-Quan

    2013-01-01

    Vertebrate Pax1 gene is a member of Pax gene family and encodes a transcription factor associated with crucial roles in the development of pharyngeal pouch, scletrotome and limb bud. In zebrafish, the genome contains two Pax1 paralogs, DrPax1a and DrPax1b, which share high sequence similarity with other Pax1 genes. To elucidate the function of zebrafish DrPax1b gene, we first examined the gene expression pattern and found that it was mainly expressed in the endodermal pharyngeal pouch, caudal somites, notochord, and fin bud. Then, we performed knockdown experiments using antisense morpholino oligonucleotides, which lead to the defects in the vertebral column, tail, pharyngeal skeleton, and pectoral fin. Additionally, we also found that the mouse MmPax1 mRNA, but not the amphioxus AmphiPax1/9 mRNA, could rescue the MO-induced defects. Furthermore, sequence alignment revealed that the N-terminal region of vertebrate Pax1 and amphioxus Pax1/9 were highly conserved, whereas their C-terminal regions were relatively divergent. However, the chimeric Am(N)Dr(C)Pax1, Mm(N)Dr(C)Pax1 and Dr(N)Mm(C)Pax1 mRNA could partially rescue the defects, while the Dr(N)Am(C)Pax1 mRNA could not. In conclusion, our data demonstrate a conserved function of DrPax1b in the development of the vertebral column, pectoral fin and pharyngeal skeleton formation in zebrafish and also provide critical insight into the functional evolution of Pax1 gene by changing its C-terminal sequence. PMID:24463529

  14. Dr. Norman Thagard, crewmember for STS-7, during training on the KC-135

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Dr. Norman E. Thagard, a physician assigned to mission specialist duties on STS-7, familiarizes himself with the donning and doffing of the extravehicular mobility unit (EMU) onboard NASA's zero gravity aircraft, the KC-135. In this view, Dr. Thagard is assisted by various technicians to don the EMU. He is wearing the hard upper and lower torso, but not the backpack, gloves or helmet.

  15. Hospital Universiti Sains Malaysia (HUSM): 25 Years Of Excellent Service.

    PubMed

    Kamari, Zaidun

    2009-01-01

    Our Hospital University Sains Malaysia (HUSM) was given the Cabinet approval to exist under the Ministry of Education on 23 November 1982. The Deputy Prime Minister during that period, Yang Berhormat Tun Musa Hitam announced this after the cabinet meeting was held together with the presence of the Yang Berhormat Ministers of Health; and Education, Director of the Public Works Department and the Implementation and Coordinating Unit, Prime Minister's Department. The first patients moved in on 14 March 1983 and the inauguration of HUSM was done on 26 August 1984 by the Duli Yang Maha Mulia Tuanku Ismail Petra Ibni Al-Marhum Sultan Yahya Petra, the Sultan of Kelantan Darul Naim. HUSM celebrated it's 25th anniversary at the Dewan Utama, USM Health Campus on the 15th December 2008 which was inaugurated by Yang Berhormat, Minister of Higher Education Dato' Seri Mohamed Khaled Nordin. USM's Vice Chancellor Professor Tan Sri Dato' Dzulkifli Abdul Razak, Chairman of the USM Board of Directors Tan Sri Dato' Haji Dr. Ani bin Arope, Health Campus Director Professor Dato' Dr. Mafauzy Mohamed, former Campus Director, Dato' Prof Mohd Roslani Abdul Majid, the current and previous Hospital Directors and Deputy Directors since 1983 were present. The achievements of HUSM since its establishment and its vision to fulfil the University's Accelerated Programme for Excellence (APEX) are elaborated. PMID:22589644

  16. Hospital Universiti Sains Malaysia (HUSM): 25 Years Of Excellent Service

    PubMed Central

    Kamari, Zaidun

    2009-01-01

    Our Hospital University Sains Malaysia (HUSM) was given the Cabinet approval to exist under the Ministry of Education on 23 November 1982. The Deputy Prime Minister during that period, Yang Berhormat Tun Musa Hitam announced this after the cabinet meeting was held together with the presence of the Yang Berhormat Ministers of Health; and Education, Director of the Public Works Department and the Implementation and Coordinating Unit, Prime Minister’s Department. The first patients moved in on 14 March 1983 and the inauguration of HUSM was done on 26 August 1984 by the Duli Yang Maha Mulia Tuanku Ismail Petra Ibni Al-Marhum Sultan Yahya Petra, the Sultan of Kelantan Darul Naim. HUSM celebrated it’s 25th anniversary at the Dewan Utama, USM Health Campus on the 15th December 2008 which was inaugurated by Yang Berhormat, Minister of Higher Education Dato’ Seri Mohamed Khaled Nordin. USM’s Vice Chancellor Professor Tan Sri Dato’ Dzulkifli Abdul Razak, Chairman of the USM Board of Directors Tan Sri Dato’ Haji Dr. Ani bin Arope, Health Campus Director Professor Dato’ Dr. Mafauzy Mohamed, former Campus Director, Dato’ Prof Mohd Roslani Abdul Majid, the current and previous Hospital Directors and Deputy Directors since 1983 were present. The achievements of HUSM since its establishment and its vision to fulfil the University’s Accelerated Programme for Excellence (APEX) are elaborated. PMID:22589644

  17. Milk Flow Rates From Bottle Nipples Used for Feeding Infants Who Are Hospitalized

    PubMed Central

    Park, Jinhee; Thoyre, Suzanne M.; Estrem, Hayley; Nix, W. Brant

    2015-01-01

    Purpose This study tested the milk flow rates and variability in flow of currently available nipples used for bottle-feeding infants who are hospitalized. Method Clinicians in 3 countries were surveyed regarding nipples available to them for feeding infants who are hospitalized. Twenty-nine nipple types were identified, and 10 nipples of each type were tested by measuring the amount of infant formula expressed in 1 min using a breast pump. Mean milk flow rate (mL/min) and coefficient of variation were used to compare nipples within brand and within category (i.e., Slow, Standard, Premature). Results Flow rates varied widely between nipples, ranging from 2.10 mL/min for the Enfamil Cross-Cut to 85.34 mL/min for the Dr. Brown's Y-Cut Standard Neck. Variability of flow rates among nipples of the same type ranged from a coefficient of variation of 0.05 for Dr. Brown's Level 1 Standard- and Wide-Neck to 0.42 for the Enfamil Cross-Cut. Mean coefficient of variation by brand ranged from 0.08 for Dr. Brown's to 0.36 for Bionix. Conclusions Milk flow is an easily manipulated variable that may contribute to the degree of physiologic instability experienced by infants who are medically fragile during oral feeding. This study provides clinicians with information to guide appropriate selection of bottle nipples for feeding infants who are hospitalized. PMID:26172340

  18. Limited field investigation report for the 100-DR-1 Operable Unit

    SciTech Connect

    Not Available

    1994-06-01

    This limited field investigation (LFI) report summarizes the data collection and analysis activities conducted during the 100-DR-1 Source Operable Unite LFI and the associated qualitative risk assessment (QRA), and makes recommendations on the continued candidacy of high-priority sites for interim remedial measures (IRM). The results and recommendations presented in this report are generally independent of future land use scenarios. The 100-DR-1 Operable Unit is one of four operable units associated with the 100 D/DR Area at the Hanford Site. The 100-DR-1 Operable Unit encompasses approximately 1.5 km{sup 2} (0.59 mi{sup 2}) and is located immediately adjacent to the Columbia River shoreline. In general, it contains waste facilities associated with the original plant facilities constructed to support D Reactor facilities, as well as cooling water retention basin systems for both D and DR Reactors. The 100-DR-1 LFI began the investigative phase of the remedial investigation for a select number of high-priority sites. The LFI was performed to provide additional data needed to support selection, design and implementation of IRM, if needed. The LFI included data compilation, nonintrusive investigations, intrusive investigations, summarization of 100 Area aggregate studies, and data evaluation.

  19. Dr John Dickinson (1832-1863): The man behind the bird.

    PubMed

    Conacher, I D

    2016-08-01

    The surgeon/naturalists Dr John Kirk, Dr Charles Meller and Dr John Dickinson, associated with the Zambezi Expedition (1857-1864) under the leadership of Dr David Livingstone are, like him, credited with the discovery of new species' of birds. A raptor, Falco dickinsoni, is named after Dr John Dickinson. Dickinson, born in the north east of England, trained in medicine in Newcastle upon Tyne. He volunteered to join the Universities' Mission to Central Africa and arrived as part of a second group to join Bishop Frederick Mackenzie, then attempting to build a Mission in Magomero, on the Shire Mountain Plateau in modern Malawi. Livingstone and Mackenzie had sown the seeds of disaster for the first UMCA venture while Dickinson was on his way to Central Africa, and his one meeting with Livingstone was trigger to a chain of events that threatened the whole expedition. Shortly after Dickinson's arrival in Magomero, Bishop Mackenzie and a fellow traveller, Reverend Henry de Wint Burrup, died. Magomero was abandoned and the remaining missionaries retrenched in Chibisa's Village on the River Shire. There, where Dickinson did most of his bird collecting, on 17 March 1863, he died of blackwater fever. Livingstone and Kirk were present at the burial. A marble cross at Chikwawa in Malawi is marker to the event that occurred on the day of Dr John Dickinson's 32nd birthday. PMID:24906404

  20. Contributions of Dr. George Washington Carver to global food security: historical reflections of Dr. Carver’s fungal plant disease survey in the southeastern United States

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Dr. George Washington Carver was a world renowned scientist whose research in the agricultural sciences in the late 1800’s and early 1900’s was critical for improving the living standards of American farmers especially in the southern United States. Although best known for developing the many uses o...

  1. Polymorphism of the HLA-D region in American blacks. A DR3 haplotype generated by recombination.

    PubMed

    Hurley, C K; Gregersen, P; Steiner, N; Bell, J; Hartzman, R; Nepom, G; Silver, J; Johnson, A H

    1988-02-01

    The polymorphism of HLA class II molecules in man is particularly evident when comparisons between population groups are made. This study describes a DR3 haplotype commonly present in the American black population. Unlike the Northern European population in which almost all DR3 individuals are DQw2, approximately 50% of DR3-positive American blacks express a serologically undefined DQ allelic product. DNA restriction fragment analysis with the use of several unrelated individuals and an informative family has allowed us to identify unique DQ alpha- and beta-fragments associated with the DR3, DQw- haplotype. Based on fragment size, the DQ alpha genes of the DR3, DQw- and DRw8, DQw- haplotypes are similar as are the DQ beta genes of DR3, DQw-; DRw8, DQw-; and DR4, DQw- haplotypes. In addition, a DX beta gene polymorphism has been identified which is associated with some DR3 haplotypes including the American black DR3, DQw- haplotype. cDNA sequence analysis has revealed a DQw2-like alpha gene and a DQ beta gene which is similar to that previously described for a DR4, DQw- haplotype. It is postulated that recombination between DQ alpha and DQ beta genes and between the DQ and DX subregions has generated the various DR3 haplotypes and has played an important role in creating diversity in the HLA-D region. PMID:2892884

  2. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    ScienceCinema

    Goyal, Amit (Oak Ridge National Laboratory)

    2012-06-28

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

  3. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    SciTech Connect

    Goyal, Amit

    2012-05-22

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

  4. Hospital pharmacy in Canada.

    PubMed

    Bachynsky, J A

    1980-04-01

    The status of Canadian hospital pharmacy and the impact of national hospital insurance on its development are discussed. The provision of health care services for Canadians is shared by the federal and provincial governments. The federal government enacts protective and regulatory legislation, compiles health statistics, promotes research, and provides direct health care for those citizens for whom it is directly responsible. Each province is responsible for hospitals, the education and training of health care professionals, public health, and the financing and administration of health insurance for all its citizens. Largely because of line-item budget allocations and a bureaucratic tendency to equalize services for the whole population, funds for existing pharmaceutical services have been assured but the introduction of upgraded or innovative programs has been difficult to achieve. The result has been an even quality of health care services, including pharmacy, throughout the country and a deficiency in clinical pharmacy programs and the trained personnel to run them. The last decade has brought advances, however, as allocation methods have changed and both hospital and insurance administrators have recognized the patient benefits and cost effectiveness of many of the newer pharmacy programs. The main challenges facing Canadian hospital pharmacy are to upgrade clinical services and education and to improve managerial and bureaucratic competence among department directors. PMID:7377213

  5. Renkioi: a forgotten Crimean War hospital and its significance.

    PubMed

    Silver, C P

    2004-12-01

    Renkioi Civil Hospital was built late in the Crimean War (1854-6) in Turkey on the Dardanelles. Designed by Isambard Kingdom Brunel, its prefabricated structure was a brilliant engineering innovation. As a civil hospital for military patients, it was staffed by experienced civilian doctors, thereby relieving the shortage of military doctors. Renkioi is remembered as an astonishing early prefabricated structure. However the war was soon to end and it was never used to near capacity. Thus, its other successful features are largely forgotten. It demonstrated the advantages of a doctors, rather than a military officer, being in complete command of a hospital and this was later accepted by the army. Renkioi also showed how infection could be reduced by able staff in a well administered, properly designed hospital with good sanitation. After the war, Dr. Edmund Parkes, its Medical Superintendent, became the first Professor of Hygiene at the new Army Medical School, ensuring that "the prevention of disease and the promotion of health" became the first function of the Army Medical Services. PMID:15822250

  6. Structural Insight for Roles of DR5 Death Domain Mutations on Oligomerization of DR5 Death Domain-FADD Complex in the Death-Inducing Signaling Complex Formation: A Computational Study.

    PubMed

    Yang, Hongyi; Song, Yuhua

    2016-04-01

    Death receptor 5 (DR5)-induced apoptosis that prioritizes the death of tumor cells has been proposed as one of the promising cancer therapies. In this process, oligomerized DR5 death domain (DD) binding to Fas-associated death domain (FADD) leads to FADD activating caspase-8, which marks the formation of the death-inducing signaling complex (DISC) that initiates apoptosis. DR5 DD mutations found in cancer cells have been suggested to play an important pathological role, the mechanism through which those mutants prevent the DR5-activated DISC formation is not clear yet. This study sought to provide structural and molecular insight for the roles of four selected DR5 DD mutations (E355K, E367K, K415N, and L363F) in the oligomerization of DR5 DD-FADD complex during the DISC formation. Results from the molecular dynamics simulations show that the simulated mutants induce conformational, dynamical motions and interactions changes in the DR5 DD-FADD tetramer complex, including changes in a protein's backbone flexibility, less exposure of FADD DED's caspase-8 binding site, reduced H-bonding and hydrophobic contacts at the DR5 DD-FADD DD binding, altered distribution of the electrostatic potentials and correlated motions of residues, and reduced binding affinity of DR5 DD binding to FADD. This study provides structural and molecular insight for the influence of DR5 DD mutations on oligomerization of DR5 DD-FADD complex, which is expected to foster understanding of the DR5 DD mutants' resistance mechanism against DR5-activated DISC formation. PMID:26995783

  7. Hospitals as interpretation systems.

    PubMed Central

    Thomas, J B; McDaniel, R R; Anderson, R A

    1991-01-01

    In this study of 162 hospitals, it was found that the chief executive officer's (CEO's) interpretation of strategic issues is related to the existing hospital strategy and the hospital's information processing structure. Strategy was related to interpretation in terms of the extent to which a given strategic issue was perceived as controllable or uncontrollable. Structure was related to the extent to which an issue was defined as positive or negative, was labeled as controllable or uncontrollable, and was perceived as leading to a gain or a loss. Together, strategy and structure accounted for a significant part of the variance in CEO interpretations of strategic events. The theoretical and managerial implications of these findings are discussed. PMID:1991677

  8. Assessment of DR-55 as a Drop-In Replacement for R-410A

    SciTech Connect

    Shen, Bo; Abdelaziz, Omar

    2016-01-01

    R410A has no ozone depletion potential (ODP), and is the most commonly used refrigerant in vapor compression systems for space cooling and heating applications. However, it has significant global warming potential with GWP higher than 1900. To mitigate the global warming effect, industry and research institutes are actively pursuing a replacement for R-410A with the following attributes, much lower GWP along with similar or higher efficiency and capacity. DR-55 (aka R452B) is a design-compatible refrigerant replacement for R-410A. It decreases the GWP by 70%, and has lower working pressure, comparable discharge temperature, and uses the same lubricant, tubing, and valves. In this study, we experimentally evaluated the performance of DR-55 as a drop-in replacement for R-410A in a high efficiency rooftop air conditioning unit. The experimental results demonstrated that DR-55 led to 5% higher efficiency at the working conditions of Integrated Energy Efficiency Rating (IEER). DR-55 also showed significantly better high ambient performance from 95 F to 125 F. In addition to the experimental study, we used the DOE/ORNL Heat Pump Design Model to model the RTU using R-410A and DR-55, respectively. The model results were compared to the laboratory measurements. The model validation demonstrates that the refrigerant heat transfer and pressure drop correlations, developed for conventional refrigerants like R-410A, are usable for DR-55. Also, a converted compressor model for DR-55, i.e. reducing volumetric and isentropic efficiencies as a function of the suction and discharge pressures from an R-410A compressor map can predict the compressor mass flow rate and power accurately.

  9. White dwarf main-sequence binaries from SDSS DR 8: unveiling the cool white dwarf population

    NASA Astrophysics Data System (ADS)

    Rebassa-Mansergas, A.; Agurto-Gangas, C.; Schreiber, M. R.; Gänsicke, B. T.; Koester, D.

    2013-08-01

    The spectroscopic catalogue of white dwarf main-sequence (WDMS) binaries from the Sloan Digital Sky Survey (SDSS) is the largest and most homogeneous sample of compact binary stars currently known. However, because of selection effects, the current sample is strongly biased against systems containing cool white dwarfs and/or early-type companions, which are predicted to dominate the intrinsic population. In this study, we present colour selection criteria that combines optical (ugriz DR 8 SDSS) plus infrared (yjhk DR 9 UKIRT Infrared Sky Survey, JHK Two Micron All Sky Survey and/or w1w2 Wide-Field Infrared Survey Explorer) magnitudes to select 3419 photometric candidates of harbouring cool white dwarfs and/or dominant (M dwarf) companions. We demonstrate that 84 per cent of our selected candidates are very likely genuine WDMS binaries, and that the white dwarf effective temperatures and secondary star spectral types of 71 per cent of our selected sources are expected to be below ≲ 10 000-15 000 K, and concentrated at ˜M2-3, respectively. We also present an updated version of the spectroscopic SDSS WDMS binary catalogue, which incorporates 47 new systems from SDSS DR 8. The bulk of the DR 8 spectroscopy is made up of main-sequence stars and red giants that were targeted as part of the Sloan Extension for Galactic Understanding and Exploration (SEGUE) Survey, therefore the number of new spectroscopic WDMS binaries in DR 8 is very small compared to previous SDSS data releases. Despite their low number, DR 8 WDMS binaries are found to be dominated by systems containing cool white dwarfs and therefore represent an important addition to the spectroscopic sample. The updated SDSS DR 8 spectroscopic catalogue of WDMS binaries consists of 2316 systems. We compare our updated catalogue with recently published lists of WDMS binaries and conclude that it currently represents the largest, most homogeneous and cleanest sample of spectroscopic WDMS binaries from SDSS.

  10. Hospital Prices Increase in California, Especially Among Hospitals in the Largest Multi-hospital Systems.

    PubMed

    Melnick, Glenn A; Fonkych, Katya

    2016-01-01

    A surge in hospital consolidation is fueling formation of ever larger multi-hospital systems throughout the United States. This article examines hospital prices in California over time with a focus on hospitals in the largest multi-hospital systems. Our data show that hospital prices in California grew substantially (+76% per hospital admission) across all hospitals and all services between 2004 and 2013 and that prices at hospitals that are members of the largest, multi-hospital systems grew substantially more (113%) than prices paid to all other California hospitals (70%). Prices were similar in both groups at the start of the period (approximately $9200 per admission). By the end of the period, prices at hospitals in the largest systems exceeded prices at other California hospitals by almost $4000 per patient admission. Our study findings are potentially useful to policy makers across the country for several reasons. Our data measure actual prices for a large sample of hospitals over a long period of time in California. California experienced its wave of consolidation much earlier than the rest of the country and as such our findings may provide some insights into what may happen across the United States from hospital consolidation including growth of large, multi-hospital systems now forming in the rest of the rest of the country. PMID:27284126

  11. Marketing the hospital library.

    PubMed

    Bridges, Jane

    2005-01-01

    Many librarians do not see themselves as marketers, but marketing is an essential role for hospital librarians. Library work involves education, and there are parallels between marketing and education as described in this article. It is incumbent upon hospital librarians actively to pursue ways of reminding their customers about library services. This article reinforces the idea that marketing is an element in many of the things that librarians already do, and includes a list of suggested marketing strategies intended to remind administrators, physicians, and other customers that they have libraries in their organizations. PMID:15982957

  12. Impact of telemedicine in hospital culture and its consequences on quality of care and safety

    PubMed Central

    Steinman, Milton; Morbeck, Renata Albaladejo; Pires, Philippe Vieira; Abreu, Carlos Alberto Cordeiro; Andrade, Ana Helena Vicente; Terra, Jose Claudio Cyrineu; Teixeira, José Carlos; Kanamura, Alberto Hideki

    2015-01-01

    ABSTRACT Objective To describe the impact of the telemedicine application on the clinical process of care and its different effects on hospital culture and healthcare practice. Methods The concept of telemedicine through real time audio-visual coverage was implemented at two different hospitals in São Paulo: a secondary and public hospital, Hospital Municipal Dr. Moysés Deutsch, and a tertiary and private hospital, Hospital Israelita Albert Einstein. Results Data were obtained from 257 teleconsultations records over a 12-month period and were compared to a similar period before telemedicine implementation. For 18 patients (7.1%) telemedicine consultation influenced in diagnosis conclusion, and for 239 patients (92.9%), the consultation contributed to clinical management. After telemedicine implementation, stroke thrombolysis protocol was applied in 11% of ischemic stroke patients. Telemedicine approach reduced the need to transfer the patient to another hospital in 25.9% regarding neurological evaluation. Sepsis protocol were adopted and lead to a 30.4% reduction mortality regarding severe sepsis. Conclusion The application is associated with differences in the use of health services: emergency transfers, mortality, implementation of protocols and patient management decisions, especially regarding thrombolysis. These results highlight the role of telemedicine as a vector for transformation of hospital culture impacting on the safety and quality of care. PMID:26676268

  13. [The hospital at Hillersleben Germany, April 1945].

    PubMed

    Weisskopf, Varda

    2014-01-01

    On 6th April 1945, nine days before the liberation of the Bergen Belsen Concentration Camp, about 2,500 Jewish prisoners were ordered to prepare to leave the camp on the next day. On 7th April, the prisoners left through the gates of the camp and began to walk about 10 kilometers to the train station near the city of Celle. There they were ordered to board a train that would take them to the Theresienstadt Concentration Camp. After six days of travel, the train stopped near the village of Farsleben, Germany, where it was liberated by the 743rd Tank Battalion of the 30th Infantry Division, of the U.S. 9th Army, on 13th April 1945. The 105th Medical Battalion of the same Division was the primary care provider for the survivors, who were then taken in vehicles available from the 30th Infantry Division, and organized into a convoy by the Division's Liaison Officer, Lt. Frank W. Towers, to the town of Hillersleben. A former German Air Force Base was located at Hillersleben with a small hospital that could not provide medical attention to all the survivors. On 21st April, Company C of the 95th Medical Battalion, received an order to go to Hillersleben. Colonel Dr. William W. Hurteau, the Commanding Officer of this Battalion, determined that the biggest task given to the Battalion during World War II, was establishing another hospital in the town of Hillersleben and providing additional beds in the existing hospital, which was a structure that had served as a boarding school. Furthermore, they needed to acquire hospital equipment which was obtained from German equipment and supplies that had been captured by the U.S. MiLitary. Also, they took care of obtaining food supplies from German warehouses, and meat and milk from local dairy farms. The lives of the prisoners on this train were saved by the heroism and dedicated work of those brave soldiers of the 30th Infantry Division and the 95th Medical Battalion. PMID:24791569

  14. The influence of hospital integration on hospital financial performance.

    PubMed

    Kim, Yang K; Stoskopf, Carleen H; Glover, Saundra H; Park, Eun C

    2004-01-01

    A clinical and functional integration strategy has a positive influence on increasing hospital revenue, and a solely functional integration strategy has a negative influence on increasing hospital expenses. Functional integration and clinical/functional integration strategies have a positive influence on hospital profit and the overall operations of the hospital. The mechanism of influence differs, however, based on the strategy used. Clinical/functional strategy has an impact on increasing hospital revenue, while functional integration strategy has an impact on reducing hospital expenses. Overall, the study shows that a functional integration strategy is more profitable than a clinical/functional integration strategy. PMID:15816230

  15. HLA-D region genes and rheumatoid arthritis (RA): importance of DR and DQ genes in conferring susceptibility to RA.

    PubMed Central

    Singal, D P; Green, D; Reid, B; Gladman, D D; Buchanan, W W

    1992-01-01

    The distribution of HLA-D region antigens was studied in three groups (I, IIa, and IIb) of patients with rheumatoid arthritis (RA): group I comprised 43 patients with mild, non-progressive RA, controlled by non-steroidal anti-inflammatory drugs without progression or erosions; group II comprised 94 patients with severe disease, who had earlier been treated with non-steroidal anti-inflammatory drugs and all had incomplete response requiring treatment with gold (sodium aurothiomalate). Of these, 46 patients (group IIa) responded to gold and the disease was well controlled, and the remaining 48 patients (group IIb) did not respond to gold and developed gold induced toxic reactions, including thrombocytopenia or proteinuria, or both. HLA-D region antigens were defined by serological and molecular (Southern blot analysis and oligonucleotide typing) techniques. The results show that DR4 was significantly increased in all three groups of patients. The prevalence of DR1, or DR1 in DR4 negative patients, and DR3 and DR4 associated DQw7 specificities, however, showed differences in these three groups of patients. The prevalence of DR1 and of DR1 in DR4 negative patients was increased only in patients with mild (group I) RA, but not in patients with severe (groups IIa and IIb) disease. On the other hand, the prevalence of DR4 associated DQw7 was significantly increased in patients with severe disease, but not in patients with mild RA. In addition, DR3 was significantly increased only in patients with severe disease who developed gold induced toxic reactions (group IIb). These data suggest that the HLA-D region genes which cause susceptibility to mild RA may be different from those causing susceptibility to severe RA. The results suggest that both DR and DQ (A, B) genes may be important in conferring susceptibility to RA: DR in mild disease and DQ in severe RA. Images PMID:1371662

  16. Expression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia

    PubMed Central

    Cavallini, Chiara; Lovato, Ornella; Bertolaso, Anna; Zoratti, Elisa; Malpeli, Giorgio; Mimiola, Elda; Tinelli, Martina; Aprili, Fiorenza; Tecchio, Cristina; Perbellini, Omar; Scarpa, Aldo; Zamò, Alberto; Cassatella, Marco Antonio; Pizzolo, Giovanni; Scupoli, Maria Teresa

    2015-01-01

    TNF-like ligand 1A (TL1A) and its unique receptor death receptor 3 (DR3) acts as broad T-cell costimulator involved in regulatory mechanisms of adaptive immune response under physiological and pathological settings. Moreover, we have recently shown that TL1A negatively regulates B-cell proliferation. Despite increasing interest on the TL1A/DR3-axis functions, very little is known on its expression and role in leukemia. In this study, we investigated the expression and function of TL1A/DR3 axis in chronic lymphocytic leukemia (CLL). DR3 was differentially expressed in activated CLL cells and predominantly detected in patients with early clinical stage disease. Soluble TL1A has been revealed in the sera of CLL patients where higher TL1A levels were associated with early stage disease. T cells, monocytes and leukemic B cells have been identified as major sources of TL1A in CLL. The relevance of these findings has been sustained by functional data showing that exogenous TL1A reduces CLL proliferation induced by stimulation of the B cell receptor. Overall, these data document the expression of the TL1A/DR3 axis in early-stage CLL. They also identify a novel function for TL1A as a negative regulator of leukemic cell proliferation that may influence the CLL physiopathology and clinical outcome at an early-stage disease. PMID:26393680

  17. RCE-DR, a novel process for coated conductor fabrication with high performance

    NASA Astrophysics Data System (ADS)

    Lee, Jae-Hun; Lee, Hunju; Lee, Jung-Woo; Choi, Soon-Mi; Yoo, Sang-Im; Moon, Seung-Hyun

    2014-04-01

    We report in detail on SuNAM’s reactive co-evaporation by deposition and reaction (RCE-DR) process. We have successfully fabricated a high performance GdBCO coated conductor (CC) with high throughput by the RCE-DR process, that consists of two steps for the deposition of elemental metal oxides and the conversion of cation oxides into the GdBCO superconducting phase. Constituting metals such as Gd, Ba and Cu were first deposited on LaMnO3 (LMO)-buffered IBAD-MgO templates at low temperatures and low pressures followed by a high temperature treatment step under high oxygen partial pressure for fast phase conversion. GdBCO CCs fabricated by RCE-DR showed excellent transport properties such as a critical current of 794 A cm-1 width at 77 K in self-field. With the RCE-DR process, we have achieved an overall processing speed of more than 120 m h-1 (in terms of a real process linear tape speed equivalent). SuNAM’s RCE-DR technique showed great potential as the highest throughput fabrication process compared with other methods developed previously for second generation high temperature superconducting wires, meeting the current and future need of industry in terms of price and production speed.

  18. Hospital structure and consumer satisfaction.

    PubMed Central

    Fleming, G V

    1981-01-01

    This study examines the relationship between hospital structural characteristics and patient satisfaction with hospital care. Teaching hospitals and private hospitals were expected to receive higher ratings of patient satisfaction than were nonteaching and government-controlled hospitals, because they generally are reputed to be technologically superior. Results show that, in general, most patients are satisfied with their hospital stays, but they are clearly more dissatisfied with their stays in teaching hospitals. Although a number of other correlates of patient satisfaction with the hospital stay are identified, no measure succeeds in reducing to insignificance the strong relationship between teaching status and dissatisfaction. Some suggestions are made as to why teaching hospital receive relatively poor evaluations from their patients. PMID:7228714

  19. Introduction to hospital information systems.

    PubMed

    Vegoda, P R

    1987-01-01

    The phrase, 'hospital information system', is frequently used in discussions about the flow of information throughout a hospital with the assumption that everybody has the same concept in mind. Closer examination shows that this is not necessarily the case. The author draws on his experience as the Chief Information Officer at University Hospital at Stony Brook to define a hospital information system in terms of the implementation at Stony Brook. The University Hospital Information System at University Hospital (UHIS), has received international acclaim and was recently selected by the IBM Quarterly of Australia as the world leader in hospital information systems. This paper answers four questions: What is a hospital information system? How does a hospital information system work? How do you implement a hospital information system? After the system is operational, where do you go, e.g., critical care data management, physician's office management? University Hospital at Stony Brook is located on eastern Long Island and is the tertiary care referral hospital for approximately 1.4 million people. Nothing in the hospital happens without computers. Doctors, nurses, administrators and staff at all levels rely on the system daily. The system operates 24 hours per day, seven days per week. Access to the system is through 300 terminals and 128 printers throughout the hospital. In addition to the UHIS terminals, the critical care management system which is called Patient Data Management System, (PDMS), is available at over 90 ICU beds and in the operating rooms. PMID:3585130

  20. [The founding of Zemun Hospital].

    PubMed

    Milanović, Jasmina; Milenković, Sanja; Pavlović, Momcilo; Stojanović, Dragos

    2014-01-01

    This year Zemun Hospital--Clinical Hospital Center Zemun celebrates 230th anniversary of continuous work, thus becoming the oldest medical facility in Serbia.The exact date of the hospital founding has been often questioned in history. Various dates appeared in the literature, but the most frequent one was 25th of February 1784. Until now, the document which confirms this has never been published. This article represents the first official publication of the document which confirms that Zemun Hospital was indeed founded on this date. The first hospitals started emerging in Zemun when the town became a part of the Habsburg Monarchy. The first sanitary facility ever formed was the"Kontumac"--a quarantine established in 1730. Soon after, two more confessional hospitals were opened.The Serbian (Orthodox) Hospital was founded before 1769, whereas the German (Catholic) Hospital started working in 1758. Both hospitals were financed, amongst others, by the Town Hall--the Magistrate. In order to improve efficiency of these hospitals, a decision was made to merge them into a single City Hospital. It was founded on 25th February 1784, when the General Command ordered the Magistrate of Zemun to merge the financess of all existing hospitals and initiate the construction of a new building. Although financially united, the hospitals continued working in separate buildings over a certain period of time.The final, physical merging of these hospitals was completed in 1795. PMID:25233701

  1. Hospital restructuring and burnout.

    PubMed

    Greenglass, Esther R; Burke, Ronald J

    2002-01-01

    Increasingly, organizations are experiencing changes as a result of extensive downsizing, restructuring, and merging. In Canada, government-sponsored medicine has been affected as hospitals have merged or closed, reducing essential medical services and resulting in extensive job loss for hospital workers, particularly nurses. Hospital restructuring has also resulted in greater stress and job insecurity in nurses. The escalation of stressors has created burnout in nurses. This study examines predictors of burnout in nurses experiencing hospital restructuring using the MBI-General Survey which yields scores on three scales: Emotional exhaustion, Cynicism, and Professional efficacy. Multiple regressions were conducted where each burnout scale was the criterion and stressors (e.g., amount of work, use of generic workers to do nurses' work), restructuring effects, social support, and individual resources (e.g., control coping, self-efficacy, prior organizational commitment) were predictors. There were differences in the amount of variance accounted for in the burnout components by stressors and resources. Stressors contributed most to emotional exhaustion and least to professional efficacy. Individual resources were more likely to contribute to professional efficacy and least to emotional exhaustion. Stressors and resources accounted for approximately equal amounts of variance in cynicism. Three conclusions were drawn. First, present findings parallel others by showing that individual coping patterns contribute to professional efficacy. Second, emotional exhaustion was found to be the prototype of stress. Third, prior organizational commitment, self-efficacy, and control coping resulted in lower burnout. PMID:15137570

  2. Hospital Library Development.

    ERIC Educational Resources Information Center

    Cramer, Anne

    Although this handbook is addressed primarily to the hopital administrator, it contains material of interest to the librarian as well. Basic requirements for providing good library services to hospital staff are identified as: (1) well chosen and well trained manpower; (2) a current collection of information materials; and (3) appropriate space in…

  3. Responsible Hospitality. Prevention Updates

    ERIC Educational Resources Information Center

    Colthurst, Tom

    2004-01-01

    Responsible Hospitality (RH)--also called Responsible Beverage Service (RBS)--encompasses a variety of strategies for reducing risks associated with the sale and service of alcoholic beverages. RH programs have three goals: (1) to prevent illegal alcohol service to minors; (2) to reduce the likelihood of drinkers becoming intoxicated; and (3) to…

  4. Cost characteristics of hospitals.

    PubMed

    Smet, Mike

    2002-09-01

    Modern hospitals are complex multi-product organisations. The analysis of a hospital's production and/or cost structure should therefore use the appropriate techniques. Flexible functional forms based on the neo-classical theory of the firm seem to be most suitable. Using neo-classical cost functions implicitly assumes minimisation of (variable) costs given that input prices and outputs are exogenous. Local and global properties of flexible functional forms and short-run versus long-run equilibrium are further issues that require thorough investigation. In order to put the results based on econometric estimations of cost functions in the right perspective, it is important to keep these considerations in mind when using flexible functional forms. The more recent studies seem to agree that hospitals generally do not operate in their long-run equilibrium (they tend to over-invest in capital (capacity and equipment)) and that it is therefore appropriate to estimate a short-run variable cost function. However, few studies explicitly take into account the implicit assumptions and restrictions embedded in the models they use. An alternative method to explain differences in costs uses management accounting techniques to identify the cost drivers of overhead costs. Related issues such as cost-shifting and cost-adjusting behaviour of hospitals and the influence of market structure on competition, prices and costs are also discussed shortly. PMID:12220092

  5. Mechanical engineering in hospitals.

    PubMed

    Wallington, J W

    1980-10-01

    The design of a modern hospital owes more to engineering than the layman may realize. In this context, many engineers are in the position of laymen, being unfamiliar with the multitude of services that lies behind the impressive facade of a modern hospital. In recent years medicine and surgery themselves have taken on many of the characteristics of a technology. This has required a matching development of the services both mechanical and electrical that are required in modern health care buildings. In medical terms, if the architectural features provide the 'skin' of the hospital, the mechanical and electrical engineering services provide the nerves and sinews. If we take as an example the recently completed Freeman Hospital, Newcastle upon Tyne, (Fig. 1), which cost 10 million pounds at current cost, the service network was responsible for about half the total cost. About 400 miles (643 km) of electrical wiring and more than 40 mile (64.5 km) of copper and steel piping were used to service 3000 separate rooms. This compares with percentages of between 18 and 25 per cent for other large buildings such as office blocks, hotels and sports complexes. PMID:10273268

  6. Peptic ulcer in hospital

    PubMed Central

    Johnson, H. Daintree

    1962-01-01

    This study corresponds to an estimated 142,250 admissions for peptic ulcer to the wards of National Health Service hospitals in England and Wales during the two years 1956 and 1957. It presents a picture of the incidence and mortality of complications and surgical treatment throughout England and Wales. PMID:14036965

  7. HOSPITAL FOOD NEEDS

    PubMed Central

    Hoskins, R. G.

    1919-01-01

    There are eight classes of men in the military hospital including attendants, and for each class there should be a different dietary. Major Hoskins explains this, tells clearly the common sources of waste of food, notes the amount, and suggests lines of conservation. Imagesp435-a PMID:18010115

  8. Deletion of a CD2-Like Gene, 8-DR, from African Swine Fever Virus Affects Viral Infection in Domestic Swine

    PubMed Central

    Borca, M. V.; Carrillo, C.; Zsak, L.; Laegreid, W. W.; Kutish, G. F.; Neilan, J. G.; Burrage, T. G.; Rock, D. L.

    1998-01-01

    An African swine fever virus (ASFV) gene with similarity to the T-lymphocyte surface antigen CD2 has been found in the pathogenic African isolate Malawi Lil-20/1 (open reading frame [ORF] 8-DR) and a cell culture-adapted European virus, BA71V (ORF EP402R) and has been shown to be responsible for the hemadsorption phenomenon observed for ASFV-infected cells. The structural and functional similarities of the ASFV gene product to CD2, a cellular protein involved in cell-cell adhesion and T-cell-mediated immune responses, suggested a possible role for this gene in tissue tropism and/or immune evasion in the swine host. In this study, we constructed an ASFV 8-DR gene deletion mutant (Δ8-DR) and its revertant (8-DR.R) from the Malawi Lil-20/1 isolate to examine gene function in vivo. In vitro, Δ8-DR, 8-DR.R, and the parental virus exhibited indistinguishable growth characteristics on primary porcine macrophage cell cultures. In vivo, 8-DR had no obvious effect on viral virulence in domestic pigs; disease onset, disease course, and mortality were similar for the mutant Δ8-DR, its revertant 8-DR.R, and the parental virus. Altered viral infection was, however, observed for pigs infected with Δ8-DR. A delay in spread to and/or replication of Δ8-DR in the draining lymph node, a delay in generalization of infection, and a 100- to 1,000-fold reduction in virus titers in lymphoid tissue and bone marrow were observed. Onset of viremia for Δ8-DR-infected animals was significantly delayed (by 2 to 5 days), and mean viremia titers were reduced approximately 10,000-fold at 5 days postinfection and 30- to 100-fold at later times; moreover, unlike in 8-DR.R-infected animals, the viremia was no longer predominantly erythrocyte associated but rather was equally distributed among erythrocyte, leukocyte, and plasma fractions. Mitogen-dependent lymphocyte proliferation of swine peripheral blood mononuclear cells in vitro was reduced by 90 to 95% following infection with 8-DR.R but

  9. Deletion of a CD2-like gene, 8-DR, from African swine fever virus affects viral infection in domestic swine.

    PubMed

    Borca, M V; Carrillo, C; Zsak, L; Laegreid, W W; Kutish, G F; Neilan, J G; Burrage, T G; Rock, D L

    1998-04-01

    An African swine fever virus (ASFV) gene with similarity to the T-lymphocyte surface antigen CD2 has been found in the pathogenic African isolate Malawi Lil-20/1 (open reading frame [ORF] 8-DR) and a cell culture-adapted European virus, BA71V (ORF EP402R) and has been shown to be responsible for the hemadsorption phenomenon observed for ASFV-infected cells. The structural and functional similarities of the ASFV gene product to CD2, a cellular protein involved in cell-cell adhesion and T-cell-mediated immune responses, suggested a possible role for this gene in tissue tropism and/or immune evasion in the swine host. In this study, we constructed an ASFV 8-DR gene deletion mutant (delta8-DR) and its revertant (8-DR.R) from the Malawi Lil-20/1 isolate to examine gene function in vivo. In vitro, delta8-DR, 8-DR.R, and the parental virus exhibited indistinguishable growth characteristics on primary porcine macrophage cell cultures. In vivo, 8-DR had no obvious effect on viral virulence in domestic pigs; disease onset, disease course, and mortality were similar for the mutant delta8-DR, its revertant 8-DR.R, and the parental virus. Altered viral infection was, however, observed for pigs infected with delta8-DR. A delay in spread to and/or replication of delta8-DR in the draining lymph node, a delay in generalization of infection, and a 100- to 1,000-fold reduction in virus titers in lymphoid tissue and bone marrow were observed. Onset of viremia for delta8-DR-infected animals was significantly delayed (by 2 to 5 days), and mean viremia titers were reduced approximately 10,000-fold at 5 days postinfection and 30- to 100-fold at later times; moreover, unlike in 8-DR.R-infected animals, the viremia was no longer predominantly erythrocyte associated but rather was equally distributed among erythrocyte, leukocyte, and plasma fractions. Mitogen-dependent lymphocyte proliferation of swine peripheral blood mononuclear cells in vitro was reduced by 90 to 95% following infection

  10. [Leadership in the hospital].

    PubMed

    Schrappe, Matthias

    2009-01-01

    Current concepts in leadership and governance on the level of supervisory board, management and departments are often considered as insufficient to cope with the profound structural change which actually takes place in the German health care system. While vertical and horizontal disconnecting is typical of the professional bureaucracy of hospitals, transition from functional to divisional structure further increases this risk. Accordingly, medical experts are oriented towards their professional peers and patient care on the one side; on the other side the management gets isolated and looses operative and strategic control. Several studies provide evidence for the relevance of role models to serve as agents of change, which are now developed into the concept of "Clinical Governance": evidence-based medicine, guidelines, continuous quality improvement, safety culture, resource accountability and organisational learning. The present situation makes it necessary to extend this conception, which focuses on the departmental level in an organisation with divisional features, to one of "Clinical Corporate Governance". This term, which also includes supervisory structures and the management board and is relevant for the total hospital and company, respectively, is based on the corporate governance concept. Inside the hospital, the management and the heads of the departments have to agree that (1) experts really need to be integrated into the decision process, and that (2) the outcomes of the entire hospital have to be regarded as equal or superior to the aims of a single department. The public image of the hospital should be one of a strong and reliable partner in health care and health care business on a local, regional and national level. Members of the supervisory board should clearly put corporate aspects above political and other implications and pay attention to personal independence from the leaders of the medical departments. PMID:19545081

  11. Autopsy radiography: digital radiographs (DR) vs multidetector computed tomography (MDCT) in high-velocity gunshot-wound victims.

    PubMed

    Harcke, H Theodore; Levy, Angela D; Abbott, Robert M; Mallak, Craig T; Getz, John M; Champion, Howard R; Pearse, Lisa

    2007-03-01

    This study compared full-body digital radiography (DR) with multidetector computed tomography (MDCT) in the postmortem evaluation of gunshot wound (GSW) victims. Thirteen consecutive male GSW victims (mean age, 27 years) had full-body DR and MDCT prior to routine autopsy. DR successfully identified all metallic fragments, but MDCT was superior in its ability to precisely determine location because it provided 3-dimensional anatomic localization. In all cases, MDCT more accurately assessed organ injuries and wound tracks. Both DR and MDCT are limited in classifying multiple wounds and major vessel injury, but MDCT is generally superior to DR. MDCT shows significant advantages over DR in the forensic evaluation of GSW victims. This is particularly advantageous for the pathologist retrieving metallic fragments and for describing fracture detail accurately. Use of MDCT instead of radiographs will require medical examiners to become familiar with reading cross-sectional images. PMID:17325457

  12. A Gambian TNF haplotype matches the European HLA-A1,B8,DR3 and Chinese HLA-A33,B58,DR3 haplotypes.

    PubMed

    Price, P; Bolitho, P; Jaye, A; Glasson, M; Yindom, L-M; Sirugo, G; Chase, D; McDermid, J; Whittle, H

    2003-07-01

    Caucasians carry TNFA-308*2 in the 8.1 ancestral haplotype (AH) (HLA-A1,B8,DR3). In Gambians, TNFA-308*2 occurs without HLA-B8 or -DR3, suggesting an independent effect of TNFA-308 on disease. Hence we sought a segment of the 8.1 AH in Gambians. BAT1 (intron 10)*2 was selected as a specific marker of the haplotype and was found with TNFA-308*2 in Gambians. Samples homozygous at TNFA-308 and BAT1 (intron 10) demonstrated identity between the African TNFA-308*2 haplotype, the 8.1AH and the Asian diabetogenic 58.1AH (HLA-A33,B58,DR3) across a region spanning BAT1, ATP6G, IKBL, LTA, TNFA, LTB, LST-1 and AIF-1. Conservation of this block in geographically distinct populations suggests a common evolutionary origin and challenges current views of the role of TNFA-308*2 in disease. PMID:12859597

  13. VizieR Online Data Catalog: PACS Evolutionary Probe (PEP-DR1) catalogs (Lutz+, 2011)

    NASA Astrophysics Data System (ADS)

    Lutz, D.; Poglitsch, A.; Altieri, B.; Andreani, P.; Aussel, H.; Berta, S.; Bongiovanni, A.; Brisbin, D.; Cava, A.; Cepa, J.; Cimatti, A.; Daddi, E.; Dominguez-Sanchez, H.; Elbaz, D.; Foerster Schreiber, N. M.; Genzel, R.; Grazian, A.; Gruppioni, C.; Harwit, M.; Le Floc'h, E.; Magdis, G.; Magnelli, B.; Maiolino, R.; Nordon, R.; Perez Garcia, A. M.; Popesso, P.; Pozzi, F.; Riguccini, L.; Rodighiero, G.; Saintonge, A.; Sanchez Portal, M.; Santini, P.; Shao, L.; Sturm, E.; Tacconi, L. J.; Valtchanov, I.; Wetzstein, M.; Wieprecht, E.

    2013-11-01

    PACS catalogs built by the PEP team, with key contributions by Stefano Berta, Benjamin Magnelli, Paola Popesso, Dieter Lutz, Francesca Pozzi, Bruno Altieri, Herve Aussel, Hoseong Hwang, Emeric Le Floc'h, Georgios Magdis, Raanan Nordon, Albrecht Poglitsch, Laurie Riguccini, Amelie Saintonge, Li Shao. For more details, please refer to Lutz et al. (2011A&A...532A..90L) and to the PDF documentation associated to the release. Data and catalogs can be retrieved from the web page http://www.mpe.mpg.de/ir/Research/PEP/publicdatareleases.php See the PDF documentation associated to the PEP DR1 release, http://www.mpe.mpg.de/resources/PEP/DR1tarballs/readmePEP_global.pdf and http://www.mpe.mpg.de/resources/PEP/DR1tarballs/readmePEP_SPIRE.pdf for more details. (69 data files).

  14. Collected Papers in Structural Mechanics Honoring Dr. James H. Starnes, Jr.

    NASA Technical Reports Server (NTRS)

    Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler); Malone, John B. (Compiler)

    2006-01-01

    This special publication contains a collection of structural mechanics papers honoring Dr. James H. Starnes, Jr. presented at the 46th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Austin, Texas, April 18-21, 2005. Contributors to this publication represent a small number of those influenced by Dr. Starnes' technical leadership, his technical prowess and diversity, and his technical breath and depth in engineering mechanics. These papers cover some of the research areas Dr. Starnes investigated, which included buckling, postbuckling, and collapse of structures; composite structural mechanics, residual strength and damage tolerance of metallic and composite structures; and aircraft structural design, certification and verification. He actively pursued technical understanding and clarity, championed technical excellence, and modeled humility and perseverance.

  15. Grating inscription in DR1:DNA-CTMA thin films: theory and experiment

    NASA Astrophysics Data System (ADS)

    Pawlik, G.; Radosz, W.; Mitus, A. C.; Mysliwiec, J.; Miniewicz, A.; Kajzar, F.; Rau, I.

    2013-10-01

    Recent experimental results indicate that the inscription of gratings in DR1:DNA-CTMA thin films displays some features of non-exponential grating amplitude growth with time.1 The origin of this behavior is hypothetically assigned to a complex distribution of local voids in a polymeric matrix1, 2 which strongly influences the dynamics of grating inscription modelled using the semi-intercalation hypothesis.3-7 We discuss critically those topics, review the theoretical methods used for modelling of the grating inscription and point-out a hypothetical relation to complex systems. New experimental results of holographic DTWM recording of the gratings in DNA-CTMA:DR1 and PS:DR1 are presented. The two observed types of dynamics are hypothetically assigned to various distributions of local voids in corresponding polymeric matrices.

  16. HLA-DR4 and career prospects in rheumatology: is there a link?

    PubMed Central

    Gough, A.; Faint, J.; Salmon, M.; Bacon, P.; Emery, P.

    1995-01-01

    OBJECTIVE--To determine whether HLA type is associated with career progress in rheumatology. DESIGN--Comparison of HLA type after HLA analysis of samples of venous blood. SETTING--Department of Rheumatology Research, University of Birmingham. SUBJECTS--All (37) staff in the department. RESULTS--All the senior academics and most staff with a PhD expressed HLA-DR4. The prevalence of expression in each of these groups was significantly greater than that found in the controls. None of the junior doctors or secretaries expressed DR4. CONCLUSION--The junior doctors in the department have poor career prospects as HLA-DR4 seems to be associated with academic achievement. Images p1666-a PMID:8541751

  17. Polyhydroxyalkanoate (PHA) production using waste vegetable oil by Pseudomonas sp. strain DR2.

    PubMed

    Song, Jin Hwan; Jeon, Che Ok; Choi, Mun Hwan; Yoon, Sung Chul; Park, Woojun

    2008-08-01

    To produce polyhydroxyalkanoate (PHA) from inexpensive substrates by bacteria, vegetable-oil-degrading bacteria were isolated from a rice field using enrichment cultivation. The isolated Pseudomonas sp. strain DR2 showed clear orange or red spots of accumulated PHA granules when grown on phosphate and nitrogen limited medium containing vegetable oil as the sole carbon source and stained with Nile blue A. Up to 37.34% (w/w) of intracellular PHA was produced from corn oil, which consisted of three major 3-hydroxyalkanoates; octanoic (C8:0, 37.75% of the total 3-hydroxyalkanoate content of PHA), decanoic (C10:0, 36.74%), and dodecanoic (C12:0, 11.36%). Pseudomonas sp. strain DR2 accumulated up to 23.52% (w/w) of PHAMCL from waste vegetable oil. The proportion of 3- hydroxyalkanoate of the waste vegetable-oil-derived PHA [hexanoic (5.86%), octanoic (45.67%), decanoic (34.88%), tetradecanoic (8.35%), and hexadecanoic (5.24%)] showed a composition ratio different from that of the corn-oil-derived PHA. Strain DR2 used three major fatty acids in the same ratio, and linoleic acid was the major source of PHA production. Interestingly, the production of PHA in Pseudomonas sp. strain DR2 could not occur in either acetate- or butyrate-amended media. Pseudomonas sp. strain DR2 accumulated a greater amount of PHA than other well-studied strains (Chromobacterium violaceum and Ralstonia eutropha H16) when grown on vegetable oil. The data showed that Pseudomonas sp. strain DR2 was capable of producing PHA from waste vegetable oil. PMID:18756101

  18. Association between risk for pre-eclampsia and HLA DR4

    SciTech Connect

    Not Available

    1990-03-17

    Dr. Kilpatrick and colleagues report results of a family study showing an association between HLA DR4 and mild and proteinuric pre-eclampsia in a British (Edinburgh) maternal population. Among 76 parous sisters of women with protein uric pre-eclampsia, they found that sisters with pregnancy-induced hypertension (pre-eclampsia with or without proteinuria) had a higher frequency of HLA DR4 antigen than did normotensive sisters. In addition, they cited unpublished findings in which they found a higher frequency of HLA DR4 antigen in a large sample of pre-eclamptic women and their babies than in appropriate controls. The authors have completed a study of HLA antigens and pregnancy outcome among a coherent of 715 black (50.9%) and white (49.1%) primigravida who were delivered at a medical center in southern USA. HLA DR typing was done by the one-color fluorescence technique with reagents. On the basis of standard criteria for diagnosis of pre-eclampsia and eclampsia, 6.9 of the cohort had mild non-proteinuric pre-eclampsia, 8.8% had pregnancy-induced hypertension, and 9.5% had combined pre-eclampsia and eclampsia. Whereas black women had higher rates than white women in all three clinical categories (eg, pregnancy-induced hypertension 10.7% vs 6.8%, respectively), differences were not significant and frequencies of HLA DR4 antigen were higher among normotensives in both races (results not shown). They therefore pooled the two racial groups for analyses.

  19. Hospital Library Development. Hospital Library Handbooks No. 2.

    ERIC Educational Resources Information Center

    Cramer, Anne

    Addressed to the administrator of the hospital as well as the librarian, this handbook covers aspects of library service policy and long-range planning. While hospitals of all sizes are discussed, a special effort is made to cover problems of small hospitals (17 to 100 beds) in sparsely-settled regions. Contents: The library as a clinical service,…

  20. BEopt-CA (Ex): A Tool for Optimal Integration of EE, DR and PV in Existing California Homes

    SciTech Connect

    Christensen, Craig; Horowitz, Scott; Maguire, Jeff; Velasco, Paulo Tabrares; Springer, David; Coates, Peter; Bell, Christy; Price, Snuller; Sreedharan, Priya; Pickrell, Katie

    2014-04-01

    This project targeted the development of a software tool, BEopt-CA (Ex) (Building Energy Optimization Tool for California Existing Homes), that aims to facilitate balanced integration of energy efficiency (EE), demand response (DR), and photovoltaics (PV) in the residential retrofit1 market. The intent is to provide utility program managers and contractors in the EE/DR/PV marketplace with a means of balancing the integration of EE, DR, and PV

  1. Doppler transcranien au cours de la drépanocytose chez l'enfant Malagasy

    PubMed Central

    Herinirina, Nicolas Fanantenana; Rajaonarison, Lova Hasina Ny Ony Narindra; Herijoelison, Andry Roussel; Rakoto, Olivat Aimée Alson; Ahmad, Ahmad

    2016-01-01

    Introduction Le doppler transcrânien est un outil efficace permettant de dépister les enfants drépanocytaires à risque d'AVC. Méthodes Nous avons réalisé une étude descriptive transversale sur des enfants Malagasy âgés entre 24 mois et 15 ans (groupe 1: 57 drépanocytaires, groupe 2: 43 témoins) afin d’évaluer le profil vélocimétrique des artères cérébrales chez les drépanocytaires. Un examen Doppler transcrânien a été réalisé avec étude des flux sanguins cérébraux chez les enfants des deux groupes. Résultats Pour les sujets drépanocytaires, la vitesse moyenne (VM) de l'artère cérébrale moyenne était de 100,9 ± 26,8 cm/s, l'indice de pulsatilité (IP) de 0,73 ± 0,20, la différence entre les artères cérébrales moyennes droite et gauche (ACMr) de 19,8 ± 21,5 cm/s, le rapport des vitesses de l'artère cérébrale antérieure/artère cérébrale moyenne (ACA/ACM) de 0,7 ± 0,2. Pour les enfants non drépanocytaires, VM: 80,6 ± 19,3 cm/s, IP: 0,79 ± 0,14, ACMr: 17 ± 20,1 cm/s, ACA/ACM: 0,8 ± 0,2. La vélocité des enfants drépanocytaires était supérieure au groupe contrôle. Les vitesses ont été corrélées avec le taux d'hémoglobine et l’âge et non pas avec le sexe et le volume globulaire moyen. Conclusion Les vitesses circulatoires cérébrales sont élevées chez les drépanocytaires que les enfants non drépanocytaires et sont influencées par le taux d'hémoglobine et l’âge.

  2. The medical ethics of the 'father of gynaecology', Dr J Marion Sims.

    PubMed Central

    Ojanuga, D

    1993-01-01

    Vesico-vaginal fistula (VVF) was a common ailment among American women in the 19th century. Prior to that time, no successful surgery had been developed for the cure of this condition until Dr J Marion Sims perfected a successful surgical technique in 1849. Dr Sims used female slaves as research subjects over a four-year period of experimentation (1845-1849). This paper discusses the controversy surrounding his use of powerless women and whether his actions were acceptable during that historical period. PMID:8459435

  3. Differential down-regulation of HLA-DR on monocyte subpopulations during systemic inflammation

    PubMed Central

    2010-01-01

    Introduction Decreased expression of human leukocyte antigen class II (HLA-DR) on monocytes is a hallmark of altered immune status in patients with a systemic inflammatory response syndrome (SIRS). So far, the analyses were mainly performed without taking into account monocytes subpopulations. Methods We studied this modification on CD14HIGH and CD14LOW monocytes of 20 SIRS patients undergoing abdominal aortic surgery (AAS), 20 patients undergoing carotid artery surgery (CAS), and 9 healthy controls, and we investigated mediators and intracellular molecules that may be involved in this process. Results HLA-DR on CD14HIGH monocytes started to decrease during surgery, after blood reperfusion, and was further reduced post-surgery. In contrast, HLA-DR expression on CD14LOW cells only decreased after surgery, and to a lesser extent than on CD14HIGH monocytes. Negative correlations were found between the reduction of HLA-DR expression and the change in cortisol levels for both subpopulations, whereas a negative correlation between interleukin-10 (IL-10) levels and HLA-DR modulation was only observed for CD14HIGH cells. In accordance with these ex vivo results, HLA-DR on CD14HIGH and CD14LOW monocytes of healthy donors was reduced following incubation with hydrocortisone, whereas IL-10 only acted on CD14HIGH subpopulation. Furthermore, flow cytometry revealed that the expression of IL-10 receptor was higher on CD14HIGH versus CD14LOW monocytes. In addition, hydrocortisone, and to a lesser extent IL-10, reversed the up-regulation of HLA-DR induced by bacterial products. Finally, membrane-associated RING-CH-1 protein (MARCH1) mRNA, a negative regulator of MHC class II, was up-regulated in monocytes of AAS patients on Day 1 post-surgery, and in those of healthy subjects exposed to hydrocortisone. Conclusions This study reveals that HLA-DR expression is modulated differently on CD14HIGH (classical) versus CD14LOW (inflammatory) monocytes after systemic inflammation. PMID

  4. Preparation and spectral characterization of polymeric nanocapsules containing DR1 organic dye

    NASA Astrophysics Data System (ADS)

    Sharifimehr, Mohammad Reza; Ghanbari, Khadijeh; Ayoubi, Kazem; Mohajerani, Ezedin

    2015-07-01

    In order to provide necessary degree of freedom for organic dye molecules in optical applications and also for safety improvement, water insoluble Disperse Red 1 (DR1) dye molecules were placed inside the polymeric nanocapsules along with suitable surfactants and using controlled phase-separation method. TEM images were used to investigate the morphology of prepared nanocapsules. Total dye concentration for a solution consist of obtained polymeric nanocapsules was determined using decomposition of nanocapsules and a reference absorption spectrum. Absorption spectrum of a solution containing DR1 and dichloromethane was also compared with prepared nanocapsules at the same dye concentration, thereby a red-shift in absorption spectrum was detected.

  5. The general NFP hospital model.

    PubMed

    Al-Amin, Mona

    2012-01-01

    Throughout the past 30 years, there has been a lot of controversy surrounding the proliferation of new forms of health care delivery organizations that challenge and compete with general NFP community hospitals. Traditionally, the health care system in the United States has been dominated by general NFP (NFP) voluntary hospitals. With the number of for-profit general hospitals, physician-owned specialty hospitals, and ambulatory surgical centers increasing, a question arises: “Why is the general NFP community hospital the dominant model?” In order to address this question, this paper reexamines the history of the hospital industry. By understanding how the “general NFP hospital” model emerged and dominated, we attempt to explain the current dominance of general NFP hospitals in the ever changing hospital industry in the United States. PMID:22324062

  6. Guide to Choosing a Hospital

    MedlinePlus

    ... the following and more: • Find hospitals by name, city, county, state, or ZIP code. • Check the results ... by the hospital name, or by ZIP Code, City, State or Territory, or County. • Select General Search, ...

  7. Human radiation studies: Remembering the early years. Oral history of Dr. George Voelz, M.D., November 29, 1994

    SciTech Connect

    1995-05-01

    Dr. George Voelz was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). This oral history covers Dr. Voelz`s research on Manhattan Engineering District plutonium workers, the acute and long term effects of radiation, his inhalation studies, and his activities at the 1961 INL reactor accident (SL-1 Reactor). After a brief biographical sketch, Dr. Voelz his remembrances on tissue studies of plutonium workers, the plutonium injection studies of 1945-1946, the controlled environmental radioiodine tests of 1963-1968, and tracer studies with human volunteers at Los Alamos. Dr. Voelz states his opinions concerning misconceptions about the Los Alamos Human Radiation Experiments.

  8. Differential regulation of RNA polymerases I, II, and III by the TBP-binding repressor Dr1.

    PubMed

    White, R J; Khoo, B C; Inostroza, J A; Reinberg, D; Jackson, S P

    1994-10-21

    RNA polymerases I, II, and III each use the TATA-binding protein (TBP). Regulators that target this shared factor may therefore provide a means to coordinate the activities of the three nuclear RNA polymerases. The repressor Dr1 binds to TBP and blocks the interaction of TBP with polymerase II- and polymerase III-specific factors. This enables Dr1 to coordinately regulate transcription by RNA polymerases II and III. Under the same conditions, Dr1 does not inhibit polymerase I transcription. By selectively repressing polymerases II and III, Dr1 may shift the physiological balance of transcriptional output in favor of polymerase I. PMID:7939686

  9. Resource Requirements Planning for Hospitals Treating Serious Infectious Disease Cases.

    SciTech Connect

    Vugrin, Eric D.; Verzi, Stephen Joseph; Finley, Patrick D.; Turnquist, Mark A.; Wyte-Lake, Tamar; Griffin, Ann R.; Ricci, Karen J.; Plotinsky, Rachel

    2015-02-01

    This report presents a mathematical model of the way in which a hospital uses a variety of resources, utilities and consumables to provide care to a set of in-patients, and how that hospital might adapt to provide treatment to a few patients with a serious infectious disease, like the Ebola virus. The intended purpose of the model is to support requirements planning studies, so that hospitals may be better prepared for situations that are likely to strain their available resources. The current model is a prototype designed to present the basic structural elements of a requirements planning analysis. Some simple illustrati ve experiments establish the mo del's general capabilities. With additional inve stment in model enhancement a nd calibration, this prototype could be developed into a useful planning tool for ho spital administrators and health care policy makers.

  10. How hospitals approach price transparency.

    PubMed

    Houk, Scott; Cleverley, James O

    2014-09-01

    A survey of finance leaders found that hospitals with lower charges were more likely than other hospitals to emphasize making prices defensible rather than simply transparent. Finance leaders of hospitals with higher charges were more likely to express concern that price transparency would cause a reduction in hospital revenue by forcing them to lower charges. Those respondents said commercial payers likely will have to agree to renegotiate contracts for price transparency to be a financially viable proposition. PMID:25647890

  11. Product lines in hospitals.

    PubMed

    Weber, J R

    1986-01-01

    The findings presented in the case study demonstrate that financial analysis is only as valid as the assumptions it is based upon. The single most important task is the definition of the clinical product. All other associated data is suspect and can lead to serious errors in business decisions if the product is poorly defined. A comprehensive case mix system, integrated with other financial systems with flexible reporting capabilities is required. The hospital and physicians must be willing to invest the time and expense necessary to ensure that the data is reliable. The hospital must be prudent in determining what cost finding approach they will elect to use. Although the RCC method has some fundamental problems, care must be taken not to develop a cost system that will require a significant amount of effort to maintain. PMID:10311387

  12. [Homicide crimes in hospitals].

    PubMed

    Dürwald, W

    1993-02-01

    Report of some cases of willful homicide in hospitals of the former GDR. In no case the patient has wished his death. Besides compassion the cause of the homicide was a large carefully expense and in two cases the attempt to prove the incapability of the competent doctor. The patients were only means to an end. All the cases are discovered by the great number of obscure death. PMID:8438538

  13. Hospital successes and failures indicate change in hospital marketing.

    PubMed

    Krampf, R F; Miller, D W

    1993-01-01

    Marketing has become an essential management function for hospitals during the past decade. A number of changes have occurred in hospital marketing as they have progressed through the marketing adoption process. A survey of Hospital CEOs reporting hospital successes and failures in the area of marketing have recently placed emphasis on sales and advertising based upon marketing research programs thus indicating entrance into the "Integrated Tactical Marketing" phase. This study also indicates that a few hospitals have entered the "Strategic Marketing Orientation" phase while future plans reported by the CEOs provide evidence that this trend is likely to continue. PMID:10129242

  14. The DR1 and DR6 First Exons of Human Herpesvirus 6A Are Not Required for Virus Replication in Culture and Are Deleted in Virus Stocks That Replicate Well in T-Cell Lines ▿ †

    PubMed Central

    Borenstein, Ronen; Zeigerman, Haim; Frenkel, Niza

    2010-01-01

    Human herpesvirus 6A (HHV-6A) and HHV-6B are lymphotropic viruses which replicate in cultured activated cord blood mononuclear cells (CBMCs) and in T-cell lines. Viral genomes are composed of 143-kb unique (U) sequences flanked by ∼8- to 10-kb left and right direct repeats, DRL and DRR. We have recently cloned HHV-6A (U1102) into bacterial artificial chromosome (BAC) vectors, employing DNA replicative intermediates. Surprisingly, HHV-6A BACs and their parental DNAs were found to contain short ∼2.7-kb DRs. To test whether DR shortening occurred during passaging in CBMCs or in the SupT1 T-cell line, we compared packaged DNAs from various passages. Restriction enzymes, PCR, and sequencing analyses have shown the following. (i) Early (1992) viral preparations from CBMCs contained ∼8-kb DRs. (ii) Viruses currently propagated in SupT1 cells contained ∼2.7-kb DRs. (iii) The deletion spans positions 60 to 5545 in DRL, including genes encoded by DR1 through the first exon of DR6. The pac-2-pac-1 packaging signals, the DR7 open reading frame (ORF), and the DR6 second exon were not deleted. (iv) The DRR sequence was similarly shortened by 5.4 kb. (v) The DR1 through DR6 first exon sequences were deleted from the entire HHV-6A BACs, revealing that they were not translocated into other genome locations. (vi) When virus initially cultured in CBMCs was passaged in SupT1 cells no DR shortening occurred. (vii) Viral stocks possessing short DRs replicated efficiently, revealing the plasticity of herpesvirus genomes. We conclude that the DR deletion occurred once, producing virus with advantageous growth “conquering” the population. The DR1 gene and the first DR6 exon are not required for propagation in culture. PMID:20053742

  15. Hospitality in College Composition Courses

    ERIC Educational Resources Information Center

    Haswell, Janis; Haswell, Richard; Blalock, Glenn

    2009-01-01

    There has been little discussion of hospitality as a practice in college writing courses. Possible misuses of hospitality as an educational and ethical practice are explored, and three traditional and still tenable modes of hospitality are described and historicized: Homeric, Judeo-Christian, and nomadic. Application of these modes to…

  16. Before Hospitalization: A Preparation Program

    ERIC Educational Resources Information Center

    Johnson, Beverly H.

    1974-01-01

    A tour of the hospital, a puppet show, and a discussion period afterwards over lemonade and cookies are all part of one hospital's efforts to prepare children and their families for the hospitalization, surgery, or other experiences young patients must undergo. (Author/CS)

  17. Hospitality Studies: Escaping the Tyranny?

    ERIC Educational Resources Information Center

    Lashley, Conrad

    2015-01-01

    Purpose: The purpose of this paper is to explore current strands in hospitality management education and research, and suggest that future programs should reflect a more social science informed content. Design/methodology/approach: The paper reviews current research in hospitality management education and in the study of hospitality and…

  18. Childrens Hospital Inservice Education Curriculum.

    ERIC Educational Resources Information Center

    Lutz, Joan

    A description is provided of a 15-month, in-service nursing education program at Childrens Hospital (Los Angeles, California). The first sections of the paper describe Childrens Hospital and provide a rationale for the hospital-based program. A listing of program goals and objectives is also provided, indicating that the curriculum is designed to…

  19. Library Hospitality: Some Preliminary Considerations

    ERIC Educational Resources Information Center

    Johnson, Eric D. M.; Kazmer, Michelle M.

    2011-01-01

    Library scholars and practitioners have frequently reflected on the various factors that in combination make up a hospitable library, but there has been little theoretical synthesis of the notion of the library as a place of hospitality. The hospitality industry provides a rich vein of theoretical material from which to draw definitions of…

  20. Hospitality Services. Student Activity Book.

    ERIC Educational Resources Information Center

    Texas Tech Univ., Lubbock. Home Economics Curriculum Center.

    This student activity book contains pencil-and-paper activities for use in a hospitality services course focusing on the food and lodging segments of the hospitality and tourism industry. The activities are organized into 29 chapters on the following topics: hospitality services industry; professional ethics; organization/management structures in…

  1. Measuring comparative hospital performance.

    PubMed

    Griffith, John R; Alexander, Jeffrey A; Jelinek, Richard C

    2002-01-01

    Leading healthcare provider organizations now use a "balanced scorecard" of performance measures, expanding information reviewed at the governance level to include financial, customer, and internal performance information, as well as providing an opportunity to learn and grow to provide better strategic guidance. The approach, successfully used by other industries, uses competitor data and benchmarks to identify opportunities for improved mission achievement. This article evaluates one set of nine multidimensional hospital performance measures derived from Medicare reports (cash flow, asset turnover, mortality, complications, length of inpatient stay, cost per case, occupancy, change in occupancy, and percent of revenue from outpatient care). The study examines the content validity, reliability and sensitivity, validity of comparison, and independence and concludes that seven of the nine measures (all but the two occupancy measures) represent a potentially useful set for evaluating most U.S. hospitals. This set reflects correctable differences in performance between hospitals serving similar populations, that is, the measures reflect relative performance and identify opportunities to make the organization more successful. PMID:11836965

  2. [The hospital ship Jutlandia].

    PubMed

    Winge, M

    1996-01-01

    The Danish contribution to the United Nations action during the Korean War (1950-52) was the hospital ship "Jutlandia". The motorvessel Jutlandia - 8.500 tons - was built by the Nakskov Shipyard in 1934, and was rebuilt in three months at the same shipyard to a modern hospital ship with 300 beds, 3 operating theatres, a dental clinic, an x-ray department etc. The crew and the hospital staff consisted approximately each of 100 persons. Jutlandia sailed for Korea on Jan. 23. 1951 and the expedition ended in Copenhagen on Oct. 16. 1953. On the first two cruises the ship was stationed at Pusan. During the first period mostly as an "evacuation sick-bay" and during the second period the ship was opened for Korean military and civil patients, and extensive help was given to the local population on shore. While in Denmark between the second and third cruise a helicopter deck was installed and the operating theatre for neuro-surgery was changed to an opthalmic clinic. This time the ship was stationed at the Bay of Ichon so close to the front, that the wounded could be admitted directly from the advanced dressing stations. On the return journeys to Europe patients were sailed to their home countries. Commodore Kai Hammerich was in charge of the expedition and captain Christen Kondrup was in charge of the ship, throughout the whole expedition. PMID:11625136

  3. Hospital mergers and market overlap.

    PubMed Central

    Brooks, G R; Jones, V G

    1997-01-01

    OBJECTIVE: To address two questions: What are the characteristics of hospitals that affect the likelihood of their being involved in a merger? What characteristics of particular pairs of hospitals affect the likelihood of the pair engaging in a merger? DATA SOURCES/STUDY SETTING: Hospitals in the 12 county region surrounding the San Francisco Bay during the period 1983 to 1992 were the focus of the study. Data were drawn from secondary sources, including the Lexis/Nexis database, the American Hospital Association, and the Office of Statewide Health Planning and Development of the State of California. STUDY DESIGN: Seventeen hospital mergers during the study period were identified. A random sample of pairs of hospitals that did not merge was drawn to establish a statistically efficient control set. Models constructed from hypotheses regarding hospital and market characteristics believed to be related to merger likelihood were tested using logistic regression analysis. DATA COLLECTION: See Data Sources/Study Setting. PRINCIPAL FINDINGS: The analysis shows that the likelihood of a merger between a particular pair of hospitals is positively related to the degree of market overlap that exists between them. Furthermore, market overlap and performance difference interact in their effect on merger likelihood. In an analysis of individual hospitals, conditions of rivalry, hospital market share, and hospital size were not found to influence the likelihood that a hospital will engage in a merger. CONCLUSIONS: Mergers between hospitals are not driven directly by considerations of market power or efficiency as much as by the existence of specific merger opportunities in the hospitals' local markets. Market overlap is a condition that enables a merger to occur, but other factors, such as the relative performance levels of the hospitals in question and their ownership and teaching status, also play a role in influencing the likelihood that a merger will in fact take place. PMID

  4. DR alpha beta dimers released from complexes with invariant chain fail to stimulate alloreactive T cell clones.

    PubMed

    Demotz, S

    1993-09-01

    To demonstrate that DR alpha beta dimers still complexed to invariant chain (Ii) have not yet acquired peptides recognized by alloreactive T cells, complexes between DR molecules and Ii isolated from Epstein-Barr-virus (EBV)-transformed B cells were analyzed by affinity chromatography and gel filtration. First, it was shown that DR/Ii complexes inserted into artificial planar membranes (PM) failed to stimulate proliferative response of five alloreactive T cell clones and a polyclonal alloreactive T cell line, while PM bearing mature DR alpha beta dimers from the same EBV-B cells were stimulatory for the T cell clones and the T cell line. These findings indicate that either Ii inhibits binding of peptides to DR molecules or Ii hinders T cells recognition of peptide/DR complexes. Second, to discriminate between these two possibilities, DR alpha beta dimers, which were artificially released from complexes between DR molecules and Ii, were inserted into PM. These DR alpha beta dimers were devoid of alloreactive stimulatory capacity while fully capable of binding and presenting a tetanus toxin synthetic peptide to a specific T cell clone, indicating that DR molecules released from complexes with Ii are empty. This study, by showing that DR molecules bound to Ii do not bear peptides recognized by alloreactive T cells, supports the notion that association of Ii with class II major histocompatibility complex (MHC) molecules prevents premature peptide loading and hence favors encounter with peptides derived from proteins of the extracellular compartment. Since allogeneic class II MHC molecules released from complexes with Ii were not stimulatory for five out of five alloreactive T cell clones and a polyclonal alloreactive T cell line, these data also indicate that, in most cases, alloreactive T cells recognize ligands constituted by complexes between allogeneic class II MHC molecules and specific peptides which derive from the antigen-presenting cells themselves or serum

  5. Isolation of distinct cDNA clones encoding HLA-DR beta chains by use of an expression assay.

    PubMed Central

    Long, E O; Wake, C T; Strubin, M; Gross, N; Accolla, R S; Carrel, S; Mach, B

    1982-01-01

    cDNA clones encoding different human Ia antigen beta chains were isolated by use of a complementation-expression assay in Xenopus oocytes. The assay was based on two previous findings. First, oocytes injected with mRNA from a human B-cell line express HLA-DR antigen. The three intracellular DR chains are assembled in oocytes and can be immunoprecipitated with anti-DR monoclonal antibodies. Second, we have isolated cDNA clones encoding DR alpha and intermediate chains. In order to identify beta-chain cDNA clones, mRNA was hybrid-selected with pools of cDNA clones, mixed with mRNA for the alpha and intermediate chains, and injected into oocytes. We isolated two distinct clones that could select DR beta-chain mRNA as demonstrated by assembly of the translation product with DR alpha chains and immunoprecipitation with DR-specific monoclonal antibodies. One clone is specific for a beta chain of the DR locus. The other clone, much weaker in its ability to select DR mRNA, encodes another Ia-like beta chain. Full-length cDNA clones corresponding to the DR and Ia-like beta chains were isolated and compared. Cross-hybridization was detectable in the coding regions but not in the 3' untranslated regions. Distinct RNAs homologous to the DR and the Ia-like beta-chain clones were present in B cells but were undetectable in three T-cell lines. Images PMID:6818545

  6. DNA restriction fragment length polymorphism of HLA-DR2 haplotypes in normal individuals and in patients with rheumatoid arthritis.

    PubMed Central

    Singal, D P; Reid, B; Green, D; Bensen, W G; D'Souza, M

    1990-01-01

    A strong association between HLA-DR4 and rheumatoid arthritis (RA) has been found in a number of populations. In contrast, the incidence of DR2 is decreased in patients with RA, suggesting that this specificity may confer some protection against the disease. A number of subtypes of DR2 have been defined by serology, by responses in mixed lymphocyte culture reaction, and, more recently, by restriction fragment length polymorphism. These subtypes of DR2 are in linkage disequilibrium with different subspecificities of DQw1. It is thus likely that the distribution of these subtypic DR,DQ haplotypes in DR2 positive patients with RA may be important in understanding the genetic basis of susceptibility/resistance to RA. In this paper a study of the subtypes of DR2,DQw1 haplotypes in 18 patients with RA, who required sodium aurothiomalate as a disease remitting drug, and unrelated healthy individuals is reported. Three subtypes of DR2 haplotypes, DRw15 (Dw2),DQw1.2(DQw6), DRw15(Dw12),DQw1.12(DQw6), and DRw16(Dw21),DQw1, AZH (DQw5), were analysed with a cDNA probe for the DQ beta gene. The data show that DR2 positive patients with RA carried either the DRw15(Dw2),DQw6 or DRw15(Dw12),DQw6 haplotype. No patient with RA was positive for the DRw16(Dw21),DQw5 subspecificity. In contrast, six of 29 (21%) normal healthy DR2,DQw1 positive individuals carried the DRw16(Dw21),DQw5 haplotype. These data together with earlier results on the distribution of the DR4,DQw7 haplotype in patients with RA support the hypothesis that DQB1 chain polymorphism may be important in determining susceptibility to severe RA. Images PMID:1969727

  7. [Hospital infection--ethical aspects].

    PubMed

    Hossne, W S

    1995-01-01

    The author focuses the question of hospital infection, analysing the background on which the control committees were created. The hospital infection is discussed under bioethical principles and the Medical Ethics Code, examining the aspects related to the government, the Hospital Directorship, the Committee and the Control Service of Hospital Infection, and the assisting physician. A closer integration between the activities of the Program of Control of Hospital Infections and those of the Medical Ethics Committee is proposed, aiming at the patient and at the community, "targets of total medical attention". PMID:7550409

  8. Citizenship Ceremony for Dr. von Braun and German-Born Scientists and Engineers

    NASA Technical Reports Server (NTRS)

    1955-01-01

    In a swearing-in ceremony held at Huntsville High School, one hundred and three German-born scientists and engineers, along with family members, took the oath of citizenship to become United States citizens. Among those taking the oath was Dr. Wernher von Braun, located in the second row, right side, third from the end.

  9. Characterizing Interstellar Ammonia Masers in the Galactic Star Forming Region DR21(OH)

    NASA Astrophysics Data System (ADS)

    Fagan, Amanda J.; Hoffman, Ian M.

    2015-01-01

    Using the Green Bank Telescope, we observed the (J,K)=(10,6), (11,6), (12,6), and (8,3) transitions of ammonia in DR21(OH). We detected neither emission nor absorption, with an upper limit of 3σ=0.11 Jy. From observations in 1984, DR21(OH) is known to have a (9,6) maser. There are three suggested possibilities for maser emission at higher rotational levels of ammonia: (1) there could be a maser in the adjacent (10,6) level, (2) there could be a maser in alternating levels, including (11,6), or (3) there could be no pumping above (9,6). NGC 7538 is known to have both a (9,6) and (10,6) maser, with a flux density ratio of 4.83:1, and no maser in either (11,6) or (12,6). If the excitation conditions in DR21(OH) are the same as in NGC 7538, a (10,6) maser with a flux density of 0.15 Jy would be expected in DR21(OH) but is not observed. Other possibilities are also discussed in detail.This work is supported by Wittenberg University through the Physics Department.

  10. If Dr. King Were a Principal: Building the "Beloved Community" in Schools

    ERIC Educational Resources Information Center

    Hillis, Michael; Woolworth, Stephen

    2008-01-01

    In this article, the authors offer a more humanistic vision of educational community, one that is substantive in content yet flexible in its application to the diverse contexts in which American schooling occurs. In doing so, the authors turn specifically to the nonviolent philosophy of Dr. Martin Luther King, Jr. and consider what a school…

  11. Connect the Book. Martin's Big Words: The Life of Dr. Martin Luther King, Jr.

    ERIC Educational Resources Information Center

    Brodie, Carolyn S.

    2005-01-01

    In honor of Martin Luther King, Jr. Day, this month's featured book is "Martin's Big Words: The Life of Dr. Martin Luther King, Jr." The book was written by Doreen Rappaport and illustrated by Bryan Collier (Jump at the Sun, 2001. 40p. ISBN 0786807148). This pictorial biography of the world-renowned civil rights leader has one of the most striking…

  12. Why We Do Not Have Ethical Conduct: A Response to Dr. Sternberg

    ERIC Educational Resources Information Center

    Carson, Jamin

    2014-01-01

    In "We Need to Teach for Ethical Conduct," Dr. Robert Sternberg argued that students act unethically because they are unable to transfer principles of ethics into practice. While I agree that this is partially the case, it is also the case that unethical behavior is a result of the prevailing educational-philosophy: radical…

  13. Study on integrated vehicle navigation system of "Beidou" Double-Star/DR

    NASA Astrophysics Data System (ADS)

    Liu, Hong; Liu, Jianye; Zhai, Linpei; Xiu, Jihong

    2005-12-01

    Vehicle navigation is the corn element of Intelligent Transport System. The integrated system of "Beidou" Double-star/DR is studied in this paper according to the present state of vehicle navigation in our country. "Beidou" Double-star navigation position system is one regional satellite position system built up by our country, which can provide rapidly not only highly precision position and brevity telegram service. However, when the vehicles go around the tall buildings, high mountain area, wayside trees and in the tunnels, all signal may not be received. If the satellite navigation position system is used only, the precision will be reduced. Therefore, this paper proposes a nonlinear self-adaptive Kalman filter model and its algorithm for a Double-star/DR integrated navigation system in land vehicles, and verifies effectively the algorithm and scheme through the means of simulation. Next, this paper introduces map match approach. The roads are segmented and character information is brought out. Then, proper search rules and map match algorithm are adopted. According to the current vehicle position information that Double-Star/DR system provides, the nearest road can be found in the map database. The vehicle position will be matched and displayed on the road. The result of the experiment shows that the Double-Star/DR integrated algorithm and map match can improve reliability and the precision of vehicle navigation system efficiently.

  14. State Environmental Policy Act (SEPA) Checklist for the 105-DR Large Sodium Fire Facility Closure Plan

    SciTech Connect

    Not Available

    1990-09-01

    The Hanford Site, located northwest of the city of Richland, Washington, houses reactors, chemical-separation systems, and related facilities used for the production of special nuclear materials, as well as for activities associated with nuclear energy development. The 105-DR Large Sodium Fire Facility (LSFF), which was in operation from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility. The LSFF was established to provide means of investigating fire and safety aspects associated with large sodium or other metal alkali fires in the liquid metal fast breeder reactor (LMFBR) facilities. The 105-DR Reactor facility was designed and built in the 1950's and is located in the 100-D Area of the Hanford Site. The building housed the DR defense reactor, which was shut down in 1964. The LSFF is subject to the regulatory requirements for the storage and treatment of dangerous wastes. Clean closure is the proposed method of closure for the LSFF. Closure will be conducted pursuant to the requirements of the Washington Administrative Code (WAC) 173-303-610 (Ecology 1989). This closure plan presents a description of the facility, the history of wastes managed, and the procedures that will be followed to close the LSFF as an Alkali Metal Treatment Facility. No future use of the LSFF is expected.

  15. African American Women Scholars and International Research: Dr. Anna Julia Cooper's Legacy of Study Abroad

    ERIC Educational Resources Information Center

    Evans, Stephanie Y.

    2009-01-01

    EIn this article, the author presents a little-known but detailed history of Black women's tradition of study abroad. Specifically, she situates Dr. Anna Julia Cooper within the landscape of historic African American students who studied in Japan, Germany, Jamaica, England, Italy, Haiti, India, West Africa, and Thailand, in addition to France. The…

  16. Advancing the Fundamental Understanding of Fission: 2014 LDRD 20120077DR Review

    SciTech Connect

    White, Morgan C.; Tovesson, Fredrik K.; Sierk, Arnold John

    2014-02-06

    The following slides were presented as part of the LDRD 20120077DR Progress Appraisal Review held Tuesday, February 4, 2014. This is part of an ongoing project assessment the previous of which was documented in LA-UR-13-21182. This presentation documents the progress made against the goals agreed to as part of the 2013 review.

  17. Aberrant esophageal HLA-DR expression in a high percentage of patients with Crohn's disease.

    PubMed

    Oberhuber, G; Püspök, A; Peck-Radosavlevic, M; Kutilek, M; Lamprecht, A; Chott, A; Vogelsang, H; Stolte, M

    1999-08-01

    Esophageal histology is not well studied in patients with Crohn's disease (CD). We, therefore, analyzed the histologic and immunohistologic appearance of esophageal mucosa in CD. Biopsy specimens taken from the esophagus of 57 consecutive patients with known CD of the large and/or small bowel, of 200 Crohn's-free controls, of 15 cases with ulcerative colitis, and of 5 cases with viral esophagitis were evaluated. In controls, most patients had either HLA-DR negative esophageal epithelium or showed focal or diffuse basal staining. HLA-DR expression of all epithelial layers (transepithelial staining) was observed in only four (2%) control subjects, in one case with herpes esophagitis, but not in patients with ulcerative colitis. In contrast, transepithelial HLA-DR expression was found in 19 (33%) patients with CD (p < 0.0001). In CD patients, it was associated with a significantly increased epithelial content in T-cells (CD3+, TIA-1+, granzyme B+), B-cells (CD79a+), natural killer cells (CD57+), and macrophages (CD68+). There was no correlation with either histological findings elsewhere in the upper gastrointestinal tract or with laboratory findings, symptoms, CDAI, or medication. Transepithelial esophageal HLA-DR expression is common in CD. Immunohistochemistry may prove useful in supporting the histologic diagnosis of CD in staging procedures, for initial diagnosis as well as in doubtful cases. PMID:10435568

  18. High-Velocity HCO Emission Associated with the DR21 Molecular Outflow

    NASA Astrophysics Data System (ADS)

    Garden, R. P.; Carlstrom, J. E.

    1996-03-01

    The spatial and velocity distribution of HCO(+) J = 1-0 line emission from the DR 21 young stellar outflow is investigated with the Hat Creek millimeter interferometer. It is argued that the HCO(+) emission arises from two spatially distinct components: low-velocity clumps bordering the central DR 21 compact H II region, and extended high-velocity gas associated with the DR 21 outflow lobes. The high-velocity HCO(+) emission associated with the outflow lobes exhibits a remarkable spatial correlation with the distribution of shock-excited H2 line emission and is most likely formed by the compression and acceleration of ambient gas on interaction with a powerful young stellar wind. It is argued that the observed spatial correlation between HCO(+) and H2 line emission results from two interrelated effects: a small enhancement in the fractional abundance of HCO(+) in the shocked gas, and the more favorable conditions for excitation of the HCO(+) ion in the warm dense gas that comprises the outflow lobes. It is suggested that the DR 21 outflow source is one of the largest, most massive and energetic young stellar outflows discovered to date.

  19. Algebra Project DR K-12 Cohorts--Demonstration Project: Summative Evaluation Report

    ERIC Educational Resources Information Center

    St. John, Mark

    2014-01-01

    The Algebra Project DR K-12, funded by the National Science Foundation as a Research and Development Project, addressed the challenge of offering significant STEM content for students to ensure public literacy and workforce readiness. The project's primary purpose was to test the feasibility and effectiveness of a model for establishing four-year…

  20. HLA-DR3 antigen in the resistance to idiopathic dilated cardiomyopathy

    PubMed Central

    Jin, B.; Wu, B.W.; Wen, Z.C.; Shi, H.M.; Zhu, J.

    2016-01-01

    Idiopathic dilated cardiomyopathy (IDC) has been hypothesized as a multifactorial disorder initiated by an environment trigger in individuals with predisposing human leukocyte antigen (HLA) alleles. Published data on the association between HLA-DR3 antigen and IDC risk are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. Studies were identified by searching the PUBMED and Embase database (starting from June 2015). A total of 19 case-control studies including 1378 cases and 10383 controls provided data on the association between HLA-DR3 antigen and genetic susceptibility to IDC. Overall, significantly decreased frequency of HLA-DR3 allele (OR=0.72; 95%CI=0.58-0.90; P=0.004) was found in patients with IDC compared with controls. When stratified by myocardial biopsy or non-biopsy cases, statistically decreased risk was found for IDC in myocardial biopsy cases (OR=0.69; 95%CI=0.57-0.84; P=0.0003). In the subgroup analysis by ethnicity, borderline statistically significantly decreased risk was found among Europeans from 12 case-control studies (OR=0.76; 95%CI=0.58-1.00; P=0.05). In conclusion, our results suggest that individuals with HLA-DR3 antigen may have a protective effect against IDC. PMID:27007655

  1. Education with Its Eyes Open. A Biography of Dr. K. S. Cunningham.

    ERIC Educational Resources Information Center

    Williams, Brian Robert

    This book is a biography of Dr. K. S. Cunningham, founding director of the Australian Council for Educational Research. Cunningham is considered one of the most influential figures in the development of education, psychology, and the social sciences in Australia. The biography examines Cunningham's early family life, his educational experiences,…

  2. Human fibroblasts in idiopathic retroperitoneal fibrosis express HLA-DR antigens.

    PubMed

    Lee, I

    1991-09-01

    Idiopathic retroperitoneal fibrosis (IRF) is a rare human disease characterized by non-neoplastic fibroblastic proliferation associated with chronic inflammatory cells; its pathogenesis is obscure. We undertook an immunohistochemical study for the expression of HLA-DR antigens and other immune-related markers by retroperitoneal proliferating fibroblasts and inflammatory cells from 2 IRF patients. Patterns of immunoreactivity were compared with those expressed by human nodular fasciitis (NF) and granulation tissue. In IRF, most fibroblasts immunostained strongly for HLA-DR antigens, whereas fibroblasts in NF and granulation tissue did, not immunostain at all. The fibroblasts did not immunostain for interleukin 2 receptor, C3b receptor, CD-4, CD-8, or Leu-M1 in any of the tissue studied. Most macrophages and lymphocytes in IRF and NF immunostained Strangly for HLA-DR antigens. In IRF, the CD-4 and CD-8 immunostained T-lymphocytes appeared equally distributed. The expression of HLA-DR antigens by fibroblasts in IRF indicates that this rare disease may indeed be an immune-associated hypersensitivity disorder. PMID:1777134

  3. Narrating International and National Trends in US Science Education: An Autobiographical Approach Showcasing Dr. Robert Yager

    ERIC Educational Resources Information Center

    Verma, Geeta; Martin-Hansen, Lisa

    2009-01-01

    This biographical piece is based on a conversation involving Bob Yager, Geeta Verma, and Lisa Martin-Hansen which took place at the National Association for Research in Science Teaching (NARST) conference in March, 2008. The unique aspect of this autobiographical piece is that it highlights Dr. Yager's account about the emergence of the science…

  4. Dr. Clarke vs. the "Ladies": Coeducation and Women's Roles in the 1870's.

    ERIC Educational Resources Information Center

    Seller, Maxine S.

    Negative reaction to the theories forwarded in Dr. Edward H. Clarke's 1873 treatise against coeducation, "Sex in Education or A Fair Chance for the Girls," has been largely neglected. The book appeared at a time when conspicuous numbers of women were extending their activities by campaigning for suffrage; working in factories, schools, and…

  5. The Research of Dr. Joanne Simpson: Fifty Years Investigating Hurricanes, Tropical Clouds and Cloud Systems

    NASA Technical Reports Server (NTRS)

    Tao, W. -K.; Halverson, J.; Adler, R.; Garstang, M.; Houze, R., Jr.; LeMone, M.; Pielke, R., Sr.; Woodley, W.; O'C.Starr, David (Technical Monitor)

    2001-01-01

    This AMS Meteorological Monographs is dedicated to Dr. Joanne Simpson for her many pioneering research efforts in tropical meteorology during her fifty-year career. Dr. Simpson's major areas of scientific research involved the "hot tower" hypothesis and its role in hurricanes, structure and maintenance of trade winds, air-sea interaction, and observations and the mechanism for hurricanes and waterspouts. She was also a pioneer in cloud modeling with the first one-dimensional model and had the first cumulus model on a computer. She also played a major role in planning and leading observational experiments on convective cloud systems. The launch of the Tropical Rainfall Measuring Mission (TRMM) satellite, a joint U.S.-Japan project, in November of 1997 made it possible for quantitative measurements of tropical rainfall to be obtained on a continuous basis over the entire global tropics. Dr. Simpson was the TRAM Project Scientist from 1986 until its launch in 1997. Her efforts during this crucial period ensured that the mission was both well planned scientifically and well engineered as well as within budget. In this paper, Dr. J. Simpson's nine specific accomplishments during her fifty-year career: (1) hot tower hypothesis, (2) hurricanes, (3) airflow and clouds over heated islands, (4) cloud models, (5) trade winds and their role in cumulus development, (6) air-sea interaction, (7) cloud-cloud interactions and mergers, (8) waterspouts, and (9) TRMM science, will be described and discussed.

  6. Dr. Wernher Von Braun at the Marshall Space Flight Center's neutral buoyancy simulator.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Dr. Wernher Von Braun, Marshall Space Flight Center director, points and asks a question about the operation of the center's neutral buoyancy facility in the Manufacturing Engineering Laboratory. The facility was used to test and evaluate hardware and operations hat were planned for Apollo applications program flights.

  7. Dr. Wernher Von Braun on Tour With U.S. congressman Armistead Seldon

    NASA Technical Reports Server (NTRS)

    1999-01-01

    U.S. representative Armistead Seldon (D.-Al) tries on an astronaut maneuvering unit mockup during a tour of the Saturn I workshop at the Marshall Space Flight center. Explaining the unit and the workshop to Representative Seldon is Dr. Wernher Von Braun, director of the Marshall Center.

  8. The first data release (DR1) of the LAMOST regular survey

    NASA Astrophysics Data System (ADS)

    Luo, A.-Li; Zhao, Yong-Heng; Zhao, Gang; Deng, Li-Cai; Liu, Xiao-Wei; Jing, Yi-Peng; Wang, Gang; Zhang, Hao-Tong; Shi, Jian-Rong; Cui, Xiang-Qun; Chu, Yao-Quan; Li, Guo-Ping; Bai, Zhong-Rui; Wu, Yue; Cai, Yan; Cao, Shu-Yun; Cao, Zi-Huang; Carlin, Jeffrey L.; Chen, Hai-Yuan; Chen, Jian-Jun; Chen, Kun-Xin; Chen, Li; Chen, Xue-Lei; Chen, Xiao-Yan; Chen, Ying; Christlieb, Norbert; Chu, Jia-Ru; Cui, Chen-Zhou; Dong, Yi-Qiao; Du, Bing; Fan, Dong-Wei; Feng, Lei; Fu, Jian-Ning; Gao, Peng; Gong, Xue-Fei; Gu, Bo-Zhong; Guo, Yan-Xin; Han, Zhan-Wen; He, Bo-Liang; Hou, Jin-Liang; Hou, Yong-Hui; Hou, Wen; Hu, Hong-Zhuan; Hu, Ning-Sheng; Hu, Zhong-Wen; Huo, Zhi-Ying; Jia, Lei; Jiang, Fang-Hua; Jiang, Xiang; Jiang, Zhi-Bo; Jin, Ge; Kong, Xiao; Kong, Xu; Lei, Ya-Juan; Li, Ai-Hua; Li, Chang-Hua; Li, Guang-Wei; Li, Hai-Ning; Li, Jian; Li, Qi; Li, Shuang; Li, Sha-Sha; Li, Xin-Nan; Li, Yan; Li, Yin-Bi; Li, Ye-Ping; Liang, Yuan; Lin, Chien-Cheng; Liu, Chao; Liu, Gen-Rong; Liu, Guan-Qun; Liu, Zhi-Gang; Lu, Wen-Zhi; Luo, Yu; Mao, Yin-Dun; Newberg, Heidi; Ni, Ji-Jun; Qi, Zhao-Xiang; Qi, Yong-Jun; Shen, Shi-Yin; Shi, Huo-Ming; Song, Jing; Song, Yi-Han; Su, Ding-Qiang; Su, Hong-Jun; Tang, Zheng-Hong; Tao, Qing-Sheng; Tian, Yuan; Wang, Dan; Wang, Da-Qi; Wang, Feng-Fei; Wang, Guo-Min; Wang, Hai; Wang, Hong-Chi; Wang, Jian; Wang, Jia-Ning; Wang, Jian-Ling; Wang, Jian-Ping; Wang, Jun-Xian; Wang, Lei; Wang, Meng-Xin; Wang, Shou-Guan; Wang, Shu-Qing; Wang, Xia; Wang, Ya-Nan; Wang, You; Wang, Yue-Fei; Wang, You-Fen; Wei, Peng; Wei, Ming-Zhi; Wu, Hong; Wu, Ke-Fei; Wu, Xue-Bing; Wu, Yu-Zhong; Xing, Xiao-Zheng; Xu, Ling-Zhe; Xu, Xin-Qi; Xu, Yan; Yan, Tai-Sheng; Yang, De-Hua; Yang, Hai-Feng; Yang, Hui-Qin; Yang, Ming; Yao, Zheng-Qiu; Yu, Yong; Yuan, Hui; Yuan, Hai-Bo; Yuan, Hai-Long; Yuan, Wei-Min; Zhai, Chao; Zhang, En-Peng; Zhang, Hua-Wei; Zhang, Jian-Nan; Zhang, Li-Pin; Zhang, Wei; Zhang, Yong; Zhang, Yan-Xia; Zhang, Zheng-Chao; Zhao, Ming; Zhou, Fang; Zhou, Xu; Zhu, Jie; Zhu, Yong-Tian; Zou, Si-Cheng; Zuo, Fang

    2015-08-01

    The Large sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signal-to-noise ratio (SNR) ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters: late A,FGK-type stars with high quality spectra (1061 918 entries), A-type stars (100 073 entries), and M-type stars (121 522 entries). This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

  9. Dr. Mary McLeod Bethune: A Life Devoted to Service

    ERIC Educational Resources Information Center

    Long, Kim Cliett

    2011-01-01

    The purpose of this paper is to explore and analyze the leadership traits of Dr. Mary McLeod Bethune, an African-American woman of history, using the servant leadership theory developed by Robert K. Greenberg and the ten characteristics of servant leadership as conceived by Larry C. Spears. This exploration seeks to identify the significant…

  10. Dr. George Mueller Follows the Progress of the Apollo 11 Mission

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Dr. George E. Mueller, Associate Administrator for Manned Space Flight, NASA, follows the progress of the Apollo 11 mission. This photo was taken on July 16, 1969 in the Launch Control Center at the Spaceport on the morning of the launch.

  11. Photographer: Digital Telepresence: Dr Murial Ross's Virtual Reality Application for Neuroscience

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Photographer: Digital Telepresence: Dr Murial Ross's Virtual Reality Application for Neuroscience Research Biocomputation. To study human disorders of balance and space motion sickness. Shown here is a 3D reconstruction of a nerve ending in inner ear, nature's wiring of balance organs.

  12. GenoType NTM-DR for Identifying Mycobacterium abscessus Subspecies and Determining Molecular Resistance.

    PubMed

    Kehrmann, Jan; Kurt, Nermin; Rueger, Kai; Bange, Franz-Christoph; Buer, Jan

    2016-06-01

    We studied the performance of a new line probe assay for identifying the subspecies and determining the macrolide and aminoglycoside resistance levels of 50 Mycobacterium abscessus isolates. Agreement of GenoType NTM-DR results with sequencing and phenotypic resistance results was 92% for subspecies identification and 98% for determining molecular and phenotypic resistance. PMID:27030487

  13. Expression of MIF and CD74 in leukemic cell lines: correlation to DR expression destiny.

    PubMed

    Georgouli, Mirella; Papadimitriou, Lina; Glymenaki, Maria; Patsaki, Valia; Athanassakis, Irene

    2016-06-01

    Invariant chain (Ii) or CD74 is a non-polymorphic glycoprotein, which apart from its role as a chaperone dedicated to MHCII molecules, is known to be a high-affinity receptor for macrophage migration inhibitory factor (MIF). The present study aimed to define the roles of CD74 and MIF in the immune surveillance escape process. Towards this direction, the cell lines HL-60, Raji, K562 and primary pre-B leukemic cells were examined for expression and secretion of MIF. Flow cytometry analysis detected high levels of MIF and intracellular/membrane CD74 expression in all leukemic cells tested, while MIF secretion was shown to be inversely proportional to intracellular HLA-DR (DR) expression. In the MHCII-negative cells, IFN-γ increased MIF expression and induced its secretion in HL-60 and K562 cells, respectively. In K562 cells, CD74 (Iip33Iip35) was shown to co-precipitate with HLA-DOβ (DOβ), inhibiting thus MIF or DR binding. Induced expression of DOα in K562 (DOα-DOβ+) cells in different transfection combinations decreased MIF expression and secretion, while increasing surface DR expression. Thus, MIF could indeed be part of the antigen presentation process. PMID:26866879

  14. Dr. Samokhotskiy's method of healing inflammation by the analysis and regulation of blood electrolyte balance.

    PubMed

    Bacherikov, Vadym V; Bacherikov, Valeriy A

    2015-01-01

    An overview of a little-known method, which was discovered by Dr. Alexander S. Samokhotskiy, for treatment of gangrenous, traumatic, and postoperative inflammation, sepsis and some other diseases, was represented. Dr. A. S. Samokhotskiy carried out numerous animal experiments and clinical trials and found that application of wet bandages and/or intravenous injection of solution containing trivalent chromium ions (Cr3+), alum, resorcinol, sodium salicylate, lactate buffer, colloidal sulphur, thioglycolic acid and glutathione with adding KCl, MgCI2, CaCl2 or NaCl solutions can heal inflammation of various etiology. Intravenous injections of particular therapeutic solution containing Na+, K+, Ca2+ or Mg2+ ions were administered in dependence on concentration of these ions in patient's blood plasma. Thousands of patients, many of them with fatal afflictions, where other methods were helpless, were healed by Dr. A. S. Samokhotskiy with the help of his method. Purpose of this publication is to inform the international medical community with the Dr. A. S. Samokhotskiy's discovery and initiate further research in this area. PMID:26259394

  15. In response to Dr. Jose AP da Silva: fall prevention with vitamin D clarifications needed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We agree with Dr. da Silva, and wish to clarify three issues raised by the recent IOM report concerning our 2009 meta-analysis on vitamin D and fall prevention. 1. The IOM questioned the inclusion of Broe et al., which did not pre-specify falls as a primary or secondary outcome. While this did viol...

  16. Proteomic insights into the functional basis for the response regulator DrRRA of Deinococcus radiodurans.

    PubMed

    Wang, Liangyan; Hu, Jing; Liu, Mengjia; Yang, Su; Zhao, Ye; Cheng, Kaiying; Xu, Guangzhi; Li, Mingfeng; Tian, Bing; Hua, Yuejin

    2016-05-01

    Purpose To investigate the function basis of the recently discovered response regulator, drRRA (DNA damage response regulator A) in Deinococcus radiodurans, we compared the proteomic profile of the radiation-sensitive drRRA mutant with that of wild-type strain under both non-stress and gamma radiation treatment. Materials and methods Total proteins of D. radiodurans cells were subjected to two-dimension electrophoresis. Protein spots in 2-Dimension gels were silver stained and scanned. Spots that changed significantly in expression levels were selected for mass spectrometry analysis. Seven genes encoding representative proteins were knocked out for stress resistance analysis. Results A total of 52 proteins displayed significant expression level changes at least 1.5-fold in the mutant relative to wild-type strain under non-stress conditions, with 31 repressed and 21 induced proteins, which might affect the cell response of D. radiodurans to gamma radiation. The proteins were distributed into functional groups including stress response, metabolism, and function unknown. Disruptions of several altered proteins including DRA0259 (Catalase E) and DR1538 (Osmotically inducible protein C), reduced the antioxidant activity of D. radiodurans. Conclusion Combined with our previous result of transcriptional profile, we further confirmed that inactivation of DrRRA affects the expression of various stress response systems. PMID:26948123

  17. Strategic Thinking on Facility Design: An Interview with Dr. Franklin Hill.

    ERIC Educational Resources Information Center

    School Business Affairs, 1996

    1996-01-01

    Dr. Franklin Hill, who has provided facility planning for over 100 schools, discusses the process that design plays in creating a learning environment. Advises school districts to pick a comprehensive planning team; involve people who can bring new ideas for consideration; price your options before you begin design; and have the design team work…

  18. It Really Is All about the Child: An Interview with Dr. Edward Hallowell

    ERIC Educational Resources Information Center

    Peters, Dane L.

    2012-01-01

    In a decade when brain research has helped people understand learning difficulties in children, and people have seen increased media attention on the use of medications to treat attention deficit/hyperactivity disorder (ADHD) in children and adults, Dr. Edward (Ned) Hallowell has worked tirelessly to educate the medical profession, parents,…

  19. HUCKLEBERRY FINN. DR. JEKYLL AND MR. HYDE. SHORT STORIES. LITERATURE CURRICULUM IV, TEACHER VERSION.

    ERIC Educational Resources Information Center

    KITZHABER, ALBERT R.

    A CURRICULUM GUIDE FOR THE TEACHING OF "HUCKLEBERRY FINN,""DR. JEKYLL AND MR. HYDE," AND FOUR SHORT STORIES WAS PRESENTED. THE SHORT STORIES WERE (1) "THE APPLE TREE" BY JOHN GALSWORTHY, (2) "THE COUNTRY OF THE BLIND" BY H.G. WELLS, (3) "A DOUBLE-DYED DECEIVER" BY O. HENRY, AND (4) "A MYSTERY OF HEROISM" BY STEPHEN CRANE. THE GUIDE PROVIDED…

  20. HUCKLEBERRY FINN. DR. JEKYLL AND MR. HYDE. SHORT STORIES. LITERATURE CURRICULUM IV, STUDENT VERSION.

    ERIC Educational Resources Information Center

    KITZHABER, ALBERT R.

    A STUDENT'S CURRICULUM GUIDE FOR THE STUDY OF "HUCKLEBERRY FINN,""DR. JEKYLL AND MR. HYDE," AND THREE SHORT STORIES WAS PRESENTED. THE SHORT STORIES INCLUDED WERE (1) "THE COUNTRY OF THE BLIND" BY H.G. WELLS (COMPLETE TEXT), (2) "A DOUBLE-DYED DECEIVER" BY O. HENRY, AND (3) "A MYSTERY OF HEROISM" BY STEPHEN CRANE (COMPLETE TEXT). STUDY QUESTIONS,…