The late Miocene elasmobranch assemblage from Cerro Colorado (Pisco Formation, Peru)

NASA Astrophysics Data System (ADS)

Landini, Walter; Altamirano-Sierra, Alì; Collareta, Alberto; Di Celma, Claudio; Urbina, Mario; Bianucci, Giovanni

2017-01-01

The new late Miocene elasmobranch assemblage from Cerro Colorado (Pisco Formation) described herein provides a first comprehensive view on the composition and structure of this community in the Pisco Basin (Peru), one of the most important Neogene Konservat-Lagerstätten of the world. The studied assemblage includes at least 21 species attributed to 10 families and 5 orders: 7 taxa are recorded for the first time in the Pisco Formation and 3 for the first time in the fossil record of Peru. Three shark-tooth bearing intervals have been recognized at Cerro Colorado. Changes in the taxonomic composition of these three fossiliferous deposits allowed us to reconstruct ecological, trophic and environmental dynamics over the stratigraphic succession of Cerro Colorado. In particular, the environmental scenario of the most diversified shark tooth-bearing interval (ST-low1) is consistent with a shallow marine coastal area, influenced by both brackish and open sea waters, dominated by a community of small mesopredator sharks that used this ecospace as reproductive ground (nursery) and recruitment area.

The Final Days of Paracas in Cerro del Gentil, Chincha Valley, Peru

PubMed Central

2016-01-01

This article describes and analyzes a highly significant archaeological context discovered in a late Paracas (400–200 BCE) sunken patio in the monumental platform mound of Cerro Gentil, located in the Chincha Valley, Peru. This patio area was used for several centuries for ritual activities, including large-scale feasting and other public gatherings. At one point late in this historical sequence people deposited a great deal of objects in what is demonstrably a single historical event. This was quickly followed by a series of minor events stratigraphically immediately above this larger event. This entire ritual process included the consumption of liquids and food, and involved the offering of whole pottery, pottery fragments, botanical remains, bone, lithics, baskets, pyro-engraved gourds, mummies, and other objects. We interpret these events as an “abandonment ceremony” or “termination ritual” during the late Paracas period, one that may have lasted for weeks or even months. The subsequent Topará occupation at the site (ca. 200 BCE- AD 100) involved the architectural enhancement of the mound area, but the pattern of use of the patio itself ended. Such a termination ritual signals a reorganization in the regional political structure of Paracas society. PMID:27144824

Progress report on LBL's numerical modeling studies on Cerro Prieto

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halfman-Dooley, S.E.; Lippman, M.J.; Bodvarsson, G.S.

1989-04-01

An exploitation model of the Cerro Prieto geothermal system is needed to assess the energy capacity of the field, estimate its productive lifetime and develop an optimal reservoir management plan. The model must consider the natural state (i.e., pre-exploitation) conditions of the system and be able to predict changes in the reservoir thermodynamic conditions (and fluid chemistry) in response to fluid production (and injection). This paper discusses the results of a three-dimensional numerical simulation of the natural state conditions of the Cerro Prieto field and compares computed and observed pressure and temperature/enthalpy changes for the 1973--1987 production period. 16 refs.,more » 24 figs., 2 tabs.« less

Interaction of cold-water aquifers with exploited reservoirs of the Cerro Prieto geothermal system

USGS Publications Warehouse

Truesdell, Alfred; Lippmann, Marcelo

1990-01-01

Cerro Prieto geothermal reservoirs tend to exhibit good hydraulic communication with adjacent cool groundwater aquifers. Under natural state conditions the hot fluids mix with the surrounding colder waters along the margins of the geothermal system, or discharge to shallow levels by flowing up fault L. In response to exploitation reservoir pressures decrease, leading to changes in the fluid flow pattern in the system and to groundwater influx. The various Cerro Prieto reservoirs have responded differently to production, showing localized near-well or generalized boiling, depending on their access to cool-water recharge. Significant cooling by dilution with groundwater has only been observed in wells located near the edges of the field. In general, entry of cool water at Cerro Prieto is beneficial because it tends to maintain reservoir pressures, restrict boiling, and lengthen the life and productivity of wells.

Genesis and evolution of the Cerro Prieto Volcanic Complex, Baja California, Mexico

NASA Astrophysics Data System (ADS)

García-Sánchez, L.; Macías, J. L.; Sosa-Ceballos, G.; Arce, J. L.; Garduño-Monroy, V. H.; Saucedo, R.; Avellán, D. R.; Rangel, E.; Layer, P. W.; López-Loera, H.; Rocha, V. S.; Cisneros, G.; Reyes-Agustín, G.; Jiménez, A.; Benowitz, J. A.

2017-06-01

The Cerro Prieto Volcanic Complex (CPVC), located in northwestern Mexico, is the only surface manifestation of the Cerro Prieto Geothermal Field, the third largest producer of geothermal energy in the world. This geothermal field and the Salton Sea in the USA sit in a pull-apart basin that belongs to the trans-tensional tectonic zone that includes the San Andreas Fault system and the Salton Trough basin to the NW and the East Pacific Rise to the SE. In spite of its strategic importance in the generation of geothermal energy, the origin of Cerro Prieto and its relationship with the geothermal reservoir were unknown. In this contribution, we discuss the origin, evolution, and mechanisms of formation of this small monogenetic volcano and the magmas that fed the system. The volcanic complex is located on top of the Cerro Prieto left lateral fault to the northwest of the Cerro Prieto Geothermal Field. The complex consists of a lava cone and a series of domes (˜0.15 km3) protruding from Tertiary sandstones and recent unconsolidated sediments of the alluvial plain of the Colorado River. The Cerro Prieto Volcanic Complex consists of seven stratigraphic units emplaced in a brief time span around 78-81 ka. Its activity began with the extrusion of a dacitic lava that came into contact with water-saturated sediments, causing brecciation of the lava. The activity continued with the emplacement of dacitic domes and a dyke that were destroyed by a phreatic explosion emplacing a lithic-rich breccia. This phreatic explosion formed a 300-m-wide and 40-m-deep circular crater. The activity then migrated ˜650 m to the SW where three dacitic lava domes were extruded and ended with the emplacement of a fissure-fed lava flow. Subsequent remobilization of the rocks in the complex has generated debris and hyperconcentrated flow deposits interbedded with fluviatile sediments in the surrounding terrain. All rocks of the CPVC are dacites with phenocrysts of plagioclase, orthopyroxene, and Fe

Paleomagnetism in the Determination of the Emplacement Temperature of Cerro Colorado Tuff Cone, El Pinacate Volcanic Field, Sonora, Mexico.

NASA Astrophysics Data System (ADS)

Rodriguez Trejo, A.; Alva-Valdivia, L. M.; Vidal Solano, J. R.; Garcia Amador, B.; Gonzalez-Rangel, J. A.

2014-12-01

Cerro Colorado Maar is located at the World Heritage Site, biosphere reserve El Pinacate and Gran Desierto del Altar, at the NNW region of Sonora, Mexico (in El Pinacate Volcanic Field). It is a tuff cone, about 1 km diameter, result of several phreatomagmatic episodes during the late Quaternary. We report paleomagnetic and rock magnetic properties from fusiform volcanic bombs obtained from the borders of Cerro Colorado. This study is based in the thermoremanent magnetization TRM normally acquired by volcanic rocks, which can be used to estimate the emplacement temperature range. We performed the experiments on 20 lithic fragments (10 cm to 20 cm approximately), taking 6-8 paleomagnetic cores from each. Rock magnetic experiments (magnetic susceptibility vs. temperature (k-T), hysteresis curves and FORC analysis, shows that the main magnetic mineral carriers of magnetization are titanomagnetite and titanohematite in different levels of intergrowth. The k-T curves suggest in many cases, only one magnetic phase, but also in other cases a second magnetic phase. Thermal demagnetization was used to demagnetize the specimens in detailed short steps and make a well-defined emplacement temperature determination ranges. We found that temperature emplacement determination range for these two magnetic phases is between 350-450 °C, and 550-580 °C, respectively. These results are consistent with those expected in an eruption of Surtsey type, showing a distinct volcanic activity compared to the other craters from El Pinacate volcanic field.

Morphological analysis of Cerro Bravo Volcano, Central Andes of Colombia

NASA Astrophysics Data System (ADS)

Arango-Palacio, E.; Murcia, H. F.; Robayo, C.; Chica, P.; Piedrahita, D. A.; Aguilar-Casallas, C.

2017-12-01

Keywords: Cerro Bravo Volcano, Volcanic landforms, Craters. Cerro Bravo Volcano (CBV) belongs to the San Diego-Cerro Machín Volcano - Tectonic Province in the Central Andes of Colombia. CVB is located 150 km NW from Bogotá, the capital of Colombia, and 25 km E from Manizales city ( 350,00 inhabitants). The volcanic activity of CBV began at 50,000 years ago and has been characterized by produce effusive and explosive (subplinian to plinian) eruptions with dacitic and andesitic in composition products. The effusive activity is evidenced by lava flows and lava domes, while the explosive activity is evidenced by pyroclastic density current deposits and pyroclastic fall deposits; some secondary deposits such as debris avalanches and lahares has been also recognised. Currently, the CBV is considered as a hazard for the Manizales city. In order to characterise the volcanic edifice, a morphological analysis was carried out and a map was created from a digital elevations model (DEM) with 12.5 m resolution as well as aerial photographs. Thus, it was possible to associate the landforms with the evolution of the volcano. Based on this analysis, it was possible to identify the base and top of the CBV edifice as 2400 and 4020 m.a.s.l., respectively, with a diameter in its major axis of 5.8 km. The volcanic edifice has four main craters opening to the north. The craters are apart from each other by heights and distances between 120 m.a.s.l. and 1 km, respectively; this geomorphology is an evidence of different eruptive stages of the volcano construction. Morphological analysis has shown that some craters were created from explosive eruptions, however the different heights between each crater suggest the creation of lava domes and their collapse as a response of the final effusive activity.

Occurrences of alunite, prophyllite, and clays in the Cerro La Tiza area, Puerto Rico

USGS Publications Warehouse

Hildebrand, Fred Adelbert; Smith, Raymond J.

1959-01-01

A deposit of hydrothermally altered rocks in the Cerro La Tiza area located between the towns of Comerio and Aguas Buenas, approximately 25 kilometers southwest of San Juan, Puerto Rico, was mapped and studied to determine the principal minerals, their extent distribution and origin, and the possibility of their economic utilization, especially in Puerto Rico. The Cerro la Tiza area is about 7? kilometers long, has an average width of about 1? kilometers and embraces a total area of approximately 15 square kilometers. The principal mineralized zone, a dike-like mass of light-colored rocks surrounded by dark-colored volcanic country rocks, occupies the crest and upper slopes of east-trending Cerro La Tiza ridge and is believed to be of Late Cretaceous or Eocene age. This zone is approximately 5,300 meters long, 430 meters wide and has an area of approximately 225 hectares (556 acres). The rocks of the mineralized zone are of mixed character and consist mainly of massive quartzose rocks and banded quartz-alunite rocks closely associated with foliated pyrophyllitic, sericitic and clayey rocks. The principal minerals in probably order of abundance are quartz, alunite, pyrophyllite, kaolin group clays (kaolinite and halloysite) and sericite. Minerals of minor abundance are native sulfure, diaspore, svanbergite (?), sunyite (?), hematite, goethite, pyrite, rutile (?) and very small quantities of unidentified minerals. The mineralized zone has broken down to deposits of earth-rock debris of Quaternary age that cover much of the slopes and flanks of Cerro La Tiza. This debris consists generally of fragments and boulders with a very large size range embedded in a clayey matrix. The distribution of the earth-rock debris with respect to the present topography and drainage suggests that it may have undergone at least two cycles of erosion. Underlying the earth-rock debris and completely enclosing the mineralized zone are country rocks of probably Late Cretaceous age. These

222Radon Concentration Measurements biased to Cerro Prieto Fault for Verify its Continuity to the Northwest of the Mexicali Valley.

NASA Astrophysics Data System (ADS)

Lazaro-Mancilla, O.; Lopez, D. L.; Reyes-Lopez, J. A.; Carreón-Diazconti, C.; Ramirez-Hernandez, J.

2009-05-01

The need to know the exact location in the field of the fault traces in Mexicali has been an important affair due that the topography in this valley is almost flat and fault traces are hidden by plow zone, for this reason, the southern and northern ends of the San Jacinto and Cerro Prieto fault zones, respectively, are not well defined beneath the thick sequence of late Holocene Lake Cahuilla deposits. The purpose of this study was to verify if Cerro Prieto fault is the continuation to the southeast of the San Jacinto Fault proposed by Hogan in 2002 who based his analysis on pre-agriculture geomorphy, relocation and analysis of regional microseismicity, and trench exposures from a paleoseismic site in Laguna Xochimilco, Mexicali. In this study, four radon (222Rn) profiles were carried out in the Mexicali Valley, first, to the SW-NE of Cerro Prieto Volcano, second, to the W-E along the highway Libramiento San Luis Río Colorado-Tecate, third, to the W-E of Laguna Xochimilco and fourth, to the W-E of the Colonia Progreso. The Radon results allow us to identify in the Cerro Prieto profile four regions where the values exceed 100 picocuries per liter (pCi/L), these regions can be associated to fault traces, one of them associated to the Cerro Prieto Fault (200 pCi/L) and other related with Michoacán de Ocampo Fault (450 pCi/L). The profile Libramiento San Luis Río Colorado-Tecate, show three regions above 100 pCi/L, two of them related to the same faults. In spite of the results of the Laguna Xochimilco, site used by Hogan (2002), the profile permit us observe three regions above the 100 pCi/L, but we can associate only one of the regions above this level to the Michoacán de Ocampo Fault, but none region to the Cerro Prieto Fault. Finally in spite of the Colonia Progreso is the shortest profile with only five stations, it shows one region with a value of 270 pCi/L that we can correlate with the Cerro Prieto Fault. The results of this study allow us to think in the

Analysis of heavy oils: Method development and application to Cerro Negro heavy petroleum: Topical report. [Metal content in Cerro Negro heavy petroleum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pearson, C.D.; Green, J.A.; Green, J.B.

1988-01-01

Nickel, vanadium, and iron were determined in distilled and chromatographically separated fractions from Cerro Negro heavy petroleum. Corresponding data were also obtained on two samples of Wilmington, California, heavy crude and one Mayan, Mexico, heavy oil for comparison. For the Cerro Negro crude, the ratio of porphyrinic to nonporphyrinic forms of metals was also determined on selected fractions using visible spectroscopy. In all four heavy petroleums, significant levels of metals were found only in the highest boiling distillate available, ca. 550-700/sup 0/C (1000-1300/sup 0/F), and the residue. Typically, the distillation residue contained >95 percent of a given metal. All crudesmore » contained metalloorganics of the following types: strongly acidic, weakly acidic, strongly basic, weakly basic, and neutral, but the relative distribution of metals among each class was crude dependent. Generally, nickel and vanadium distributions for a given crude followed one another very closely, while those for iron were often inconclusive because of poor mass balances for that element. Attempts to concentrate metalloorganics through liquid chromatographic separation methods largely unsuccessful. The wide variety of types of metal-containing compounds in the crudes examined precluded the use of a single approach for their isolation or preconcentration. 21 refs., 1 fig., 12 tabs.« less

Extension of the Cerro Prieto field and zones in the Mexicali Valley with geothermal possibilities in the future

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fonseca L, H.L.; de la Pena L, A.; Puente C, I.

This study concerns the possible extension of the Cerro Prieto field and identification of other zones in the Mexicali Valley with geothermal development potential by assessing the structural geologic conditions in relation to the regional tectonic framework and the integration of geologic and geophysical surveys carried out at Cerro Prieto. This study is based on data obtained from the wells drilled to date and the available geological and geophysical information. With this information, a geologic model of the field is developed as a general description of the geometry of what might be the geothermal reservoir of the Cerro Prieto field.more » In areas with geothermal potential within the Mexicali Valley, the location of irrigation wells with anomalous temperatures was taken as a point of departure for subsequent studies. Based on this initial information, gravity and magnetic surveys were made, followed by seismic reflection and refraction surveys and the drilling of 1200-m-deep multiple-use wells. Based on the results of the final integration of these studies with the geology of the region, it is suggested that the following areas should be explored further: east of Cerro Prieto, Tulecheck, Riito, Aeropuerto-Algodones, and San Luis Rio Colorado, Sonora.« less

The impact of the eruptions of Mt. Pinatubo and Cerro Hudson on Antarctic aerosol levels during the 1991 Austral spring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pitts, M.C.; Thomason, L.W.

1993-11-19

At the beginning of 1991 Austral spring, volcanic aerosols from Mt. Pinatubo and Cerro Hudson were present in the polar stratosphere of the Southern Hemisphere. Satellite observations of aerosol extinction were used to identify and track the movement of these aerosols in the vicinity of the Antarctic vortex during August through November 1991. A layer of mature Mt. Pinatubo aerosols was identified near 21 km and a layer of fresh Cerro Hudson aerosols was identified near 12 km. This altitude separation of the Mt. Pinatubo and Cerro Hudson aerosols was observed throughout the period. Below 15 km, the polar stratospheremore » was subject to episodes of strong wave activity which transported the Cerro Hudson aerosols poleward and, after the middle of September, they became a persistent feature beneath the vortex. Above 15 km, signatures of Mt. Pinatubo aerosols were observed near the vortex boundary, but significant portions of the vortex interior remained free of any detectable intrusions of Mt. Pinatubo aerosols until the final warming in mid-November. 13 refs., 4 figs.« less

Precision gravity studies at Cerro Prieto: a progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grannell, R.B.; Kroll, R.C.; Wyman, R.M.

A third and fourth year of precision gravity data collection and reduction have now been completed at the Cerro Prieto geothermal field. In summary, 66 permanently monumented stations were occupied between December and April of 1979 to 1980 and 1980 to 1981 by a LaCoste and Romberg gravity meter (G300) at least twice, with a minimum of four replicate values obtained each time. Station 20 alternate, a stable base located on Cerro Prieto volcano, was used as the reference base for the third year and all the stations were tied to this base, using four to five hour loops. Themore » field data were reduced to observed gravity values by (1) multiplication with the appropriate calibration factor; (2) removal of calculated tidal effects; (3) calculation of average values at each station, and (4) linear removal of accumulated instrumental drift which remained after carrying out the first three reductions. Following the reduction of values and calculation of gravity differences between individual stations and the base stations, standard deviations were calculated for the averaged occupation values (two to three per station). In addition, pooled variance calculations were carried out to estimate precision for the surveys as a whole.« less

Archaeological Sites Inventory of the Training Area 10 and 12 Portions of the Pinon Canyon Maneuver Site, Las Animas County, Colorado. Volume 2

DTIC Science & Technology

2004-01-01

the Hartville Uplift source) and obsidian. The source location for this obsidian is the Jemez Mountains of New Mexico (Cerro del Medio dome, Appendix...Mountain (Polvadera Peak, Obsidian Ridge, and Cerro del Medio sources in New Mexico ), Malad (Idaho) and Yellowstone (Wyoming) obsidian, Plate...5LA8308, 61 14 160 8 39 157 48 nm nm nm nm nm Cerro del Medio . FS # 15 ±7 ±4 ±5 ±3 ±4 ±4 ±3 New Mexico 5LA8309, 73 21 151 8 41 150 49 nm nm nm nm nm Cerro

Magma-Tectonic Interactions along the Central America Volcanic Arc: Insights from the August 1999 Magmatic and Tectonic Event at Cerro Negro, Nicaragua

NASA Astrophysics Data System (ADS)

La Femina, P.; Connor, C.; Strauch, W.

2002-12-01

Volcanic vent alignments form parallel to the direction of maximum horizontal stress, accommodating extensional strain via dike injection. Roughly east-west extension within the Central America Volcanic Arc is accommodated along north-northwest-trending basaltic vent alignments. In Nicaragua, these alignments are located in a northwest-trending zone of dextral shear, with shear accommodated along northeast trending bookshelf faults. The recent eruption of Cerro Negro volcano, Nicaragua and Marabios Range seismic swarm revealed the interaction of these fault systems. A low energy (VEI 1), small volume (0.001 km3 DRE) eruption of highly crystalline basalt occurred at Cerro Negro volcano, Nicaragua, August 5-7, 1999. This eruption followed three tectonic earthquakes (each Mw 5.2) in the vicinity of Cerro Negro hours before the onset of eruptive activity. The temporal and spatial pattern of microseismicity and focal mechanisms of the Mw 5.2 earthquakes suggests the activation of northeast-trending faults northwest and southeast of Cerro Negro within the Marabios Range. The eruption was confined to three new vents formed on the southern flank of Cerro Negro along a preexisting north-northwest trending alignment; the El Hoyo alignment of cinder cones, maars and explosion craters. Surface ruptures formed > 1 km south and southeast of the new vents suggest dike injection. Numerical simulations of conduit flow illustrate that the observed effusion rates (up to 65 ms-1) and fountain heights (50-300 m) can be achieved by eruption of magma with little or no excess fluid pressure, in response to tectonic strain. These observations and models suggest that 1999 Cerro Negro activity is an excellent example of tectonically induced small-volume eruptions in an arc setting.

Results of the first order leveling surveys in the Mexicali Valley and at the Cerro Prieto field

DOE Office of Scientific and Technical Information (OSTI.GOV)

de la Pena L, A.

1981-01-01

The results obtained from the third leveling survey carried out by the Direccion General de Geografia del Territorio Nacional (previously DETENAL) during November and December 1979 are presented. Calculations of the changes in field elevation and plots showing comparisons of the 1977, 1978, and 1979 surveys are also presented. Results from a second order leveling survey performed to ascertain the extent of ground motion resulting from the 8 June 1980 earthquake are presented. This magnitude ML = 6.7 earthquake with epicenter located 15 km southeast of the Guadalupe Victoria village, caused fissures on the surface, the formation of small sandmore » volcanos, and the ejection of ground water in the vicinity of the Cerro Prieto field. This leveling survey was carried out between benchmark BN-10067 at the intersection of the Solfatara canal and the Sonora-Baja California railroad, and benchmark BN-10055 located at the Delta station.« less

Site Description | CTIO

Science.gov Websites

Preserving the Dark Skies La Oficina de Protección de la Calidad del Cielo del Norte de Chile - OPCC Light view Cerro Pachón CTIO/AURA La Serena Facilities The "El Totoral" Reserve, Cerro Tololo and . back to top Sky Brightness over Cerro Pachón and Cerro Tololo Light pollution from nearby cities (La

Recycling of water, carbon, and sulfur during subduction of serpentinites: A stable isotope study of Cerro del Almirez, Spain

NASA Astrophysics Data System (ADS)

Alt, Jeffrey C.; Garrido, Carlos J.; Shanks, W. C.; Turchyn, Alexandra; Padrón-Navarta, José Alberto; López Sánchez-Vizcaíno, Vicente; Gómez Pugnaire, María Teresa; Marchesi, Claudio

2012-04-01

We use the concentrations and isotope compositions of water, carbon, and sulfur in serpentinites and their dehydration products to trace the cycling of volatiles during subduction. Antigorite serpentinites from the Cerro del Almirez complex, Spain, contain 9-12 wt.% H2O and 910 ± 730 ppm sulfur, and have bulk δ18O values of 8.6 ± 0.4‰, δD = - 54 ± 5‰, and δ34S = 5.0‰, consistent with serpentinization at temperatures of ~ 200 °C by seawater hydrothermal fluids in a seafloor setting. The serpentinites were dehydrated to chlorite-harzburgite (olivine + orthopyroxene + chlorite) at 700 °C and 1.6-1.9 GPa during subduction metamorphism, resulting in loss of water, and sulfur. The chlorite-harzburgites contain 5.7 ± 1.9 wt.% H2O, and have bulk δ18O = 8.0 ± 0.9‰, and δD = - 77 ± 11‰. The rocks contain 650 ± 620 ppm sulfur having δ34S = 1.2‰. Dehydration of serpentinite resulted in loss of 5 wt.% H2O having δ18O = 8-10‰ and δD = - 27 to - 65‰, and loss of 260 ppm sulfur as sulfate, having δ34S = 14.5‰. The contents and δ13C of total carbon in the two rock types overlap, with a broad trend of decreasing carbon contents and δ13C from ~ 1300 to 200 ppm and - 9.6 to - 20.2‰. This reflects mixing between reduced carbon in the rocks (210 ppm, δ13C ≈ - 26‰) and seawater-derived carbonate (δ13C ≈ - 1‰). Our results indicate: 1) Serpentinized oceanic peridotites carry significant amounts of isotopically fractionated water, carbon and sulfur into subduction zones; 2) Subduction of serpentinites to high P and T results in loss of water, and sulfur, which can induce melting and contribute to 18O, D, and 34S enrichments and oxidation of the sub-arc mantle wedge; and 3) Isotopically fractionated water, carbon, and sulfur in serpentinite dehydration products are recycled deeper into the mantle where they can contribute to isotope heterogeneities and may be significant for volatile budgets of the deep Earth.

Temporal Variations of Magnetic Field Associated with Seismic Activity at Cerro Machin Volcano, Colombia

NASA Astrophysics Data System (ADS)

Londono, J. M.; Serna, J. P.; Guzman, J.

2011-12-01

A study of magnetic variations was carried out at Cerro Machin Volcano, Colombia for the period 2009 -2010, with two permanent magnetometers located at South and North of the central dome, separated about 2.5 km each other. After corrections, we found that there is no clear correlation between volcanic seismicity and temporal changes of magnetic field for each magnetometer station, if they are analyzed individually. On the contrary, when we calculated the residual Magnetic field (RMF), for each magnetometer, and then we made the subtraction between them, and plot it vs time, we found a clear correlation of changes in local magnetic field with the occurrence of volcanic seismicity (ML >1.6). We found a change in the RMF between 1584 nT and 1608 nT, each time that a volcano-tectonic earthquake occurred. The máximum lapse time between the previous change in RMF and the further occurrence of the earthquake is 24 days, with an average of 11 days. This pattern occurred more than 9 times during the studied period. Based on the results, we believed that the simple methodology proposed here, is a good tool for monitoring changes in seismicity associated with activity at Cerro Machín volcano. We suggest that the temporal changes of RMF at Cerro Machín Volcano, are associated with piezo-magnetic effects, due to changes in strain-stress inside the volcano, produced by the interaction between local faulting and magma movement.

Evolution of the Cerro Prieto geothermal system as interpreted from vitrinite reflectance under isothermal conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barker, C.E.; Pawlewicz, M.J.; Bostick, N.H.

1981-01-01

Temperature estimates from reflectance data in the Cerro Prieto system correlate with modern temperature logs and temperature estimates from fluid inclusion and oxygen isotope geothermometry indicating that the temperature in the central portion of the Cerro Prieto System is now at its historical maximum. Isoreflectance lines formed by contouring vitrinite reflectance data for a given isothermal surface define an imaginary surface that indicates an apparent duration of heating in the system. The 250/sup 0/C isothermal surface has a complex dome-like form suggesting a localized heat source that has caused shallow heating in the central portion of this system. Isoreflectance linesmore » relative to this 250/sup 0/C isothermal surface define a zone of low reflectance roughly corresponding to the crest of the isothermal surface. Comparison of these two surfaces suggest that the shallow heating in the central portion of Cerro Prieto is young relative to the heating (to 250/sup 0/C) on the system margins. Laboratory and theoretical models of hydrothermal convection cells suggest that the form of the observed 250/sup 0/C isothermal surface and the reflectance surface derived relative to it results from the convective rise of thermal fluids under the influence of a regional hydrodynamic gradient that induces a shift of the hydrothermal heating effects to the southwest.« less

Dating thermal events at Cerro Prieto using fission track annealing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanford, S.J.; Elders, W..

1981-01-01

Data from laboratory experiments and geologic fading studies were compiled from published sources to produce lines of iso-annealing for apatite in time-temperature space. Fission track ages were calculated for samples from two wells at Cerro Prieto, one with an apparently simple and one with an apparently complex thermal history. Temperatures were estimated by empirical vitrinite reflectance geothermometry, fluid inclusion homogenization and oxygen isotope equilibrium. These estimates were compared with logs of measured borehole temperatures.

Subsurface Connections and Magma Mixing as revealed by Olivine- and Pyroxene-Hosted Melt Inclusions from Cerro Negro Volcano and the Las Pilas-El Hoyo Complex, Nicaragua.

NASA Astrophysics Data System (ADS)

Venugopal, S.; Moune, S.; Williams-Jones, G.

2015-12-01

Cerro Negro, the youngest volcano in the Central American Volcanic Belt, is a polygenetic cinder cone with relatively frequent explosive basaltic eruptions. Las Pilas, on the other hand, is a much larger and older complex with milder and less frequent eruptions. Based on historical data, these two closely spaced volcanoes have shown concurrent eruptive behavior, suggesting a subsurface connection. To further investigate this link, melt inclusions, which are blebs of melt trapped in growing crystals, were the obvious choice for optimal comparison of sources and determination of pre-eruptive volatile contents and magmatic conditions. Olivine-hosted inclusions were chosen for both volcanoes and pyroxene-hosted inclusions were also sampled from Las Pilas to represent the evolved melt. Major, volatile and trace elements reveal a distinct geochemical continuum with Cerro Negro defining the primitive end member and Las Pilas representing the evolved end member. Volatile contents are high for Cerro Negro (up to 1260 ppm CO2, 4.27 wt% H2O and 1700 ppm S) suggesting that volatile exsolution is likely the trigger for Cerro Negro's explosive eruptions. Las Pilas volatile contents are lower but consistent with degassing and evolutionary trends shown by major oxides. Trace element contents are rather unique and suggest Cerro Negro magmas fractionally crystallize while Las Pilas magmas are the products of mixing. Magmatic conditions were estimated with major and volatile contents: at least 2.4 kbar and 1170 °C for Cerro Negro melts and 1.3 kbar and 1130 °C for Las Pilas melts with an overall oxygen fugacity at the NNO buffer. In combination with available literature data, this study suggests an interconnected subsurface plumbing system and thus Cerro Negro should be considered as the newest vent within the Las Pilas-El Hoyo Complex.

Metagenomic analysis of the bovine hindgut from Salmonella Kentucky and Cerro-shedding dairy cows

USDA-ARS?s Scientific Manuscript database

In the United States Salmonella enterica subsp. enterica serovars Kentucky and Cerro are frequently isolated from dairy cows that appear asymptomatic. Although they are not major contributors to the salmonellosis burden, these serovars have been implicated in human clinical cases in recent years. To...

Recycling of water, carbon, and sulfur during subduction of serpentinites: A stable isotope study of Cerro del Almirez, Spain

USGS Publications Warehouse

Alt, Jeffrey C.; Garrido, Carlos J.; Shanks, Wayne C.; Turchyn, Alexandra; Padrón-Navarta, José Alberto; López Sánchez-Vizcaíno, Vicente; Gómez Pugnaire, María Teresa; Marchesi, Claudio

2012-01-01

We use the concentrations and isotope compositions of water, carbon, and sulfur in serpentinites and their dehydration products to trace the cycling of volatiles during subduction. Antigorite serpentinites from the Cerro del Almirez complex, Spain, contain 9–12 wt.% H2O and 910 ± 730 ppm sulfur, and have bulk δ18O values of 8.6 ± 0.4‰, δD = − 54 ± 5‰, and δ34S = 5.0‰, consistent with serpentinization at temperatures of ~ 200 °C by seawater hydrothermal fluids in a seafloor setting. The serpentinites were dehydrated to chlorite–harzburgite (olivine + orthopyroxene + chlorite) at 700 °C and 1.6–1.9 GPa during subduction metamorphism, resulting in loss of water, and sulfur. The chlorite–harzburgites contain 5.7 ± 1.9 wt.% H2O, and have bulk δ18O = 8.0 ± 0.9‰, and δD = − 77 ± 11‰. The rocks contain 650 ± 620 ppm sulfur having δ34S = 1.2‰. Dehydration of serpentinite resulted in loss of 5 wt.% H2O having δ18O = 8–10‰ and δD = − 27 to − 65‰, and loss of 260 ppm sulfur as sulfate, having δ34S = 14.5‰. The contents and δ13C of total carbon in the two rock types overlap, with a broad trend of decreasing carbon contents and δ13C from ~ 1300 to 200 ppm and − 9.6 to − 20.2‰. This reflects mixing between reduced carbon in the rocks (210 ppm, δ13C ≈ − 26‰) and seawater-derived carbonate (δ13C ≈ − 1‰). Our results indicate: 1) Serpentinized oceanic peridotites carry significant amounts of isotopically fractionated water, carbon and sulfur into subduction zones; 2) Subduction of serpentinites to high P and T results in loss of water, and sulfur, which can induce melting and contribute to 18O, D, and 34S enrichments and oxidation of the sub-arc mantle wedge; and 3) Isotopically fractionated water, carbon, and sulfur in serpentinite dehydration products are recycled deeper into the mantle where they can contribute to isotope heterogeneities and may be significant for volatile budgets of the deep Earth.

Proterotheriidae (Mammalia, Litopterna) from the Cerro Azul Formation (late Miocene), La Pampa Province, Argentina

NASA Astrophysics Data System (ADS)

Schmidt, G. I.; Montalvo, C. I.; Sostillo, R.; Cerdeño, E.

2018-04-01

Remains of Proterotheriidae (Litopterna) recovered from different localities in La Pampa Province, Argentina, are described. The fossiliferous levels in these localities correspond to the Cerro Azul Formation (late Miocene), where Chasicoan and Huayquerian faunal associations are known. The specimens of Proterotheriidae herein studied are assigned to Diplasiotherium pampa, Eoauchenia primitiva, cf. Brachytherium cuspidatum, Neobrachytherium sp. and Proterotheriidae indet. Although the holotype of D. pampa (left mandibular fragment with p3-m2) was defined in a previous paper, it is figured and fully described here, and its m3 is now known among the new collected specimens. Eoauchenia, Brachytherium and Neobrachytherium are registered in La Pampa Province for the first time, and the record of E. primitiva extends back to late Miocene its temporal distribution. Proterotheriids from the Cerro Azul Formation gather exclusive elements and others related to taxa represented in different Argentinean geological units corresponding to late Miocene-early Pliocene period.

Reconnaissance study of late quaternary faulting along cerro GoDen fault zone, western Puerto Rico

USGS Publications Warehouse

Mann, P.; Prentice, C.S.; Hippolyte, J.-C.; Grindlay, N.R.; Abrams, L.J.; Lao-Davila, D.

2005-01-01

The Cerro GoDen fault zone is associated with a curvilinear, continuous, and prominent topographic lineament in western Puerto Rico. The fault varies in strike from northwest to west. In its westernmost section, the fault is ???500 m south of an abrupt, curvilinear mountain front separating the 270- to 361-m-high La CaDena De San Francisco range from the Rio A??asco alluvial valley. The Quaternary fault of the A??asco Valley is in alignment with the bedrock fault mapped by D. McIntyre (1971) in the Central La Plata quadrangle sheet east of A??asco Valley. Previous workers have postulated that the Cerro GoDen fault zone continues southeast from the A??asco Valley and merges with the Great Southern Puerto Rico fault zone of south-central Puerto Rico. West of the A??asco Valley, the fault continues offshore into the Mona Passage (Caribbean Sea) where it is characterized by offsets of seafloor sediments estimated to be of late Quaternary age. Using both 1:18,500 scale air photographs taken in 1936 and 1:40,000 scale photographs taken by the U.S. Department of Agriculture in 1986, we iDentified geomorphic features suggestive of Quaternary fault movement in the A??asco Valley, including aligned and Deflected drainages, apparently offset terrace risers, and mountain-facing scarps. Many of these features suggest right-lateral displacement. Mapping of Paleogene bedrock units in the uplifted La CaDena range adjacent to the Cerro GoDen fault zone reveals the main tectonic events that have culminated in late Quaternary normal-oblique displacement across the Cerro GoDen fault. Cretaceous to Eocene rocks of the La CaDena range exhibit large folds with wavelengths of several kms. The orientation of folds and analysis of fault striations within the folds indicate that the folds formed by northeast-southwest shorTening in present-day geographic coordinates. The age of Deformation is well constrained as late Eocene-early Oligocene by an angular unconformity separating folDed, Deep

Respiratory tract deposition efficiencies: evaluation of effects from smoke released in the Cerro Grande forest fire.

PubMed

Schöllnberger, H; Aden, J; Scott, B R

2002-01-01

Forest-fire smoke inhaled by humans can cause various health effects. This smoke contains toxic chemicals and naturally occurring radionuclides. In northern New Mexico, a large wildfire occurred in May 2000. Known as the Cerro Grande Fire, it devastated the town of Los Alamos and damaged Los Alamos National Laboratory (LANL). Residents were concerned about the possible dissemination of radionuclides from LANL via smoke from the fire. To evaluate potential health effects of inhaling radionuclides contained in the smoke from the Cerro Grande Fire, it was first necessary to evaluate how much smoke would deposit in the human respiratory tract. The purpose of this study was to evaluate respiratory-tract deposition efficiencies of airborne forest-fire smoke for persons of different ages exposed while inside their homes. Potential non-radiological health effects of a forest fire are reviewed. The deposition efficiencies presented can be used to evaluate in-home smoke deposition in the respiratory tract and expected radionuclide intake related to forest fires. The impact of smoke exposure on firemen fighting a forest fire is quantitatively discussed and compared. They primarily inhaled forest-fire smoke while outdoors where the smoke concentration was much higher than inside. Radionuclides released at the LANL site via the Cerro Grande Fire were restricted to naturally occurring radionuclides from burning trees and vegetation. Radiation doses from inhaled airborne radionuclides to individuals inside and outside the Los Alamos area were likely very small.

Healthy Municipios in Latin America.

PubMed

Restrepo, H E; Llanos, G; Contreras, A; Rocabado, F; Gross, S; Suárez, J; González, J

1995-09-01

This article describes the Healthy Municipios movement in Latin America and gives examples of some PAHO projects that could become demonstration projects. The Healthy Municipios movement was established in the early 1990s. The movement aims to promote healthy municipalities according to objectives set forth in the 1987 Ottawa Charter on Health Promotion, the 1992 Declaration of Bogota, and the 1993 Caribbean Health Promotion Charter. The movement is a joint effort of government, the health sector, and the community in promoting health locally. Key features of the movement are its creativity, variety, political strength, and adaptation to local conditions. Technical cooperation serves the purpose of facilitating information exchange and promotes the use of modern techniques of analysis and scientific and technical information. All projects shared the following common features: initiation by the local community with strong political commitment, intersectoral organizational structure, widespread community mobilization and participation, problem solving activities, and a recognizable leader. Pioneering projects include the Comprehensive Project for Cienfuegos, Cuba; the Health Manizales, Colombia; the Network in Mexico; Baruta and El Hatillo, Venezuela; Valdivia, Chile; and San Carlos Canton, Costa Rica. It is concluded that these projects and most others aim to assure equity. These efforts are important for placing health on the political agenda and implementing healthy policies. The Valdivia project, for example, serves a population of about 120,000 in the urban city of Valdivia, the semi-urban area, and rural areas. The project was officially sanctioned by the President of Chile on World Health Day in 1993. Progress was reported in mass communication and school-based programs. Attention was directed also to prevention of risk factors for noncommunicable diseases and to the problem of traffic accidents.

Impact of Santiago de Chile urban atmospheric pollution on anthropogenic trace elements enrichment in snow precipitation at Cerro Colorado, Central Andes

NASA Astrophysics Data System (ADS)

Cereceda-Balic, F.; Palomo-Marín, M. R.; Bernalte, E.; Vidal, V.; Christie, J.; Fadic, X.; Guevara, J. L.; Miro, C.; Pinilla Gil, E.

2012-02-01

Seasonal snow precipitation in the Andes mountain range is evaluated as an environmental indicator of the composition of atmospheric emissions in Santiago de Chile metropolitan area, by measuring a set of representative trace elements in snow samples by ICP-MS. Three late winter sampling campaigns (2003, 2008 and 2009) were conducted in three sampling areas around Cerro Colorado, a Central Andes mountain range sector NE of Santiago (36 km). Nevados de Chillán, a sector in The Andes located about 500 km south from the metropolitan area, was selected as a reference area. The experimental results at Cerro Colorado and Nevados de Chillán were compared with previously published data of fresh snow from remote and urban background sites. High snow concentrations of a range of anthropogenic marker elements were found at Cerro Colorado, probably derived from Santiago urban aerosol transport and deposition combined with the effect of mining and smelting activities in the area, whereas Nevados de Chillán levels roughly correspond to urban background areas. Enhanced concentrations in surface snow respect to deeper samples are discussed. Significant differences found between the 2003, 2008 and 2009 anthropogenic source markers profiles at Cerro Colorado sampling points were correlated with changes in emission sources at the city. The preliminary results obtained in this study, the first of this kind in the southern hemisphere, show promising use of snow precipitation in the Central Andes as a suitable matrix for receptor model studies aimed at identifying and quantifying pollution sources in Santiago de Chile.

Cerro de Pasco and other massive sulfide deposits of central Peru

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheney, E.S.

1985-01-01

The famous Cerro de Pasco Pb-Zn-Ag deposit historically has been considered to be hydrothermally derived from an adjacent Tertiary volcanic vent. However, texturally massive pyrite-chert and pyrite-sphalerite-galena in the deposit have the same strike and cross folds as the adjacent pre-Tertiary strata. Both the deposit and the strata are cut by one of the large Longitudinal Faults. Both dikes and pyrite-enargite veins associated with the vent cut the massive sulfides; fragments of massive pyrite occur in the vent. A few examples of laminated pyrite and chert, banded pyrite and chert, banded pyrite and sphalerite, and banded pyrite, sphalerite, and galenamore » are preserved in the massive sulfide portion of the deposit. The deposit has the composition and zoning patterns typical of shale-hosted massive sulfides. Cerro de Pasco probably in part of the pelitic Devonian Excelsior formation. The Colquijirca deposit 8 km to the south and the San Cristobal district 110 km to the south likewise have been considered to be Tertiary volcanic hydrothermal deposits. Colquijirca consists of stratigraphically controlled mantos of layered pyrite, chert and tuff in the Tertiary Calera formation. The mantos of the San Cristobal district are along the upper contact of the pyritic, Permian, Catalina felsic volcanic rocks; some ore consists of laminated pyrite and sphalerite. Tertiary plutons are conspicuously absent at San Cristobal, and the ores are brecciated by Tertiary folding.« less

Cerro Papayo: an astronomical, calendrical and traditional landmark in Ancient Mexico.

NASA Astrophysics Data System (ADS)

Galindo Trejo, J.; Aguilera, T.; Montero García, I. A.

Cerro Papayo is a peculiar formed hill (almost perfect semisphere, 3,630 m) situated at the east side of the Valley of Mexico. According to surface reconnaissance there is on its cusp a prehispanic site and a modern shrine dedicated to the Virgin of Guadalupe. Its striking appearance and its unobstructed visibility from anyplace in the Valley were used, since preclassic up to postclassic periods, to mark at sunrise the moment of precise astronomical, calendrical and traditional events. The present work shows observational evidence from Cuicuilco, the Templo Mayor of Tenochtitlan and Tepeyacac.

Diverse subaerial and sublacustrine hot spring settings of the Cerro Negro epithermal system (Jurassic, Deseado Massif), Patagonia, Argentina

NASA Astrophysics Data System (ADS)

Guido, Diego M.; Campbell, Kathleen A.

2012-06-01

The Late Jurassic (~ 150 Ma) Cerro Negro volcanic-epithermal-geothermal system (~ 15 km2 area), Deseado Massif, Patagonia, Argentina, includes two inferred volcanic emission centers characterized by rhyolitic domes linked along NW-SE regional faults that are associated with deeper level Au/Ag mineralization to the NW, and with shallow epithermal quartz veins and mainly travertine surface hot spring manifestations to the SE. Some travertines are silica-replaced, and siliceous and mixed silica-carbonate geothermal deposits also are found. Five hot spring-related facies associations were mapped in detail, which show morphological and textural similarities to Pleistocene-Recent geothermal deposits at Yellowstone National Park (U.S.A.), the Kenya Rift Valley, and elsewhere. They are interpreted to represent subaerial travertine fissure ridge/mound deposits (low-flow spring discharge) and apron terraces (high-flow spring discharge), as well as mixed silica-carbonate lake margin and shallow lake terrace vent-conduit tubes, stromatolitic mounds, and volcano-shaped cones. The nearly 200 mapped fossil vent-associated deposits at Cerro Negro are on a geographical and numerical scale comparable with subaerial and sublacustrine hydrothermal vents at Mammoth Hot Springs, and affiliated with Yellowstone Lake, respectively. Overall, the Cerro Negro geothermal system yields paleoenvironmentally significant textural details of variable quality, owing to both the differential preservation potential of particular subaerial versus subaqueous facies, as well as to the timing and extent of carbonate diagenesis and silica replacement of some deposits. For example, the western fault associated with the Eureka epithermal quartz vein facilitated early silicification of the travertine deposits in the SE volcanic emission center, thereby preserving high-quality, microbial macro- and micro-textures of this silica-replaced "pseudosinter." Cerro Negro provides an opportunity to reconstruct

Contaminación por mercurio de leche materna de madres lactantes de municipios de Antioquia con explotación minera de oro.

PubMed

Molina, Carlos Federico; Arango, Catalina María; Sepúlveda, Hernán

2018-05-01

Introducción. La leche materna es esencial para el desarrollo del ser humano, pero puede contener sustancias tóxicas provenientes de la contaminación ambiental, especialmente en las áreas mineras.Objetivo. Determinar la prevalencia de la contaminación con mercurio de la leche materna de mujeres lactantes residentes en los municipios con explotación minera de oro.Materiales y métodos. Se hizo un estudio transversal de 150 madres lactantes de cuatro municipios mineros de Antioquia (El Bagre, Segovia, Remedios y Zaragoza), a quienes se les hizo una encuesta sobre factores sociodemográficos, ocupacionales y ambientales relacionados con el mercurio, y se les tomaron muestras de leche materna, de orina y de cabello. Se calculó el promedio de la concentración de mercurio y las prevalencias municipales de contaminación.Resultados. El promedio de la concentración de mercurio en la leche materna fue de 2,5 (± desviación estándar 9,2) μg/L. La prevalencia de muestras de leche materna con niveles altos de mercurio fue de 11,7 %.Conclusión. En este estudio se evidencia un grave problema en las regiones mineras auríferas de Antioquia por el efecto de la contaminación con mercurio en sectores de la población más vulnerable.

Gases in steam from Cerro Prieto geothermal wells with a discussion of steam/gas ratio measurements

USGS Publications Warehouse

Nehring, N.L.; Fausto, L.J.J.

1979-01-01

As part of a joint USGS-CFE geochemical study of Cerro Prieto, steam samples were collected for gas analyses in April, 1977. Analyses of the major gas components of the steam were made by wet chemistry (for H2O,CO2,H2S and NH3) and by gas chromatography (He,H2,Ar,O2,N2 and hydrocarbons). The hydrocarbon gases in Cerro Prieto steam closely resemble hydrocarbons in steam from Larderello, Italy and The Geysers, California which, although they are vapor-dominated rather than hot-water geothermal systems, also have sedimentary aquifer rocks. These sedimentary geothermal hydrocarbons are characterized by the presence of branched C4-6 compounds and a lack of unsaturated compounds other than benzene. Relatively large amounts of benzene may be characteristic of high-temperature geothermal systems. All hydrocarbons in these gases other than methane most probably originate from the thermal metamorphosis of organic matter contained in the sediments. ?? 1979.

Analysis of heavy oils: Method development and application to Cerro Negro heavy petroleum

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1989-12-01

On March 6, 1980, the US Department of Energy (DOE) and the Ministry of Energy and Mines of Venezuela (MEMV) entered into a joint agreement which included analysis of heavy crude oils from the Venezuelan Orinoco oil belt. The purpose of this report is to present compositional data and describe new analytical methods obtained from work on the Cerro Negro Orinoco belt crude oil since 1980. Most of the chapters focus on the methods rather than the resulting data on Cerro Negro oil, and results from other oils obtained during the verification of the method are included. In addition, publishedmore » work on analysis of heavy oils, tar sand bitumens, and like materials is reviewed, and the overall state of the art in analytical methodology for heavy fossil liquids is assessed. The various phases of the work included: distillation and determination of routine'' physical/chemical properties (Chapter 1); preliminary separation of >200{degrees} C distillates and the residue into acid, base, neutral, saturated hydrocarbon and neutral-aromatic concentrates (Chapter 2); further separation of acid, base, and neutral concentrates into subtypes (Chapters 3--5); and determination of the distribution of metal-containing compounds in all fractions (Chapter 6).« less

Cerro Grande Fire Impact to Water Quality and Stream Flow near Los Alamos National Laboratory: Results of Four Years of Monitoring

DOE Office of Scientific and Technical Information (OSTI.GOV)

B.M. Gallaher; R.J. Koch

2004-09-15

In May 2000, the Cerro Grande fire burned about 7400 acres of mixed conifer forest on the Los Alamos National Laboratory (LANL), and much of the 10,000 acres of mountainside draining onto LANL was severely burned. The resulting burned landscapes raised concerns of increased storm runoff and transport of contaminants by runoff in the canyons traversing LANL. The first storms after the fire produced runoff peaks that were more than 200 times greater than prefire levels. Total runoff volume for the year 2000 increased 50% over prefire years, despite a decline in total precipitation of 13% below normal and amore » general decrease in the number of monsoonal thunderstorms. The majority of runoff in 2000 occurred in the canyons at LANL south of Pueblo Canyon (70%), where the highest runoff volume occurred in Water Canyon and the peak discharge occurred in Pajarito Canyon. This report describes the observed effects of the Cerro Grande fire and related environmental impacts to watersheds at and near Los Alamos National Laboratory (LANL) for the first four runoff seasons after the fire, from 2000 through 2003. Spatial and temporal trends in radiological and chemical constituents that were identified as being associated with the Cerro Grande fire and those that were identified as being associated with historic LANL discharges are evaluated with regard to impacts to the Rio Grande and area reservoirs downstream of LANL. The results of environmental sampling performed by LANL, the New Mexico Environment Department (NMED), and U.S. Geological Survey (USGS) after the Cerro Grande fire are included in the evaluation. Effects are described for storm runoff, baseflow, stream sediments, and area regional reservoir sediment.« less

Electromagnetically Inferred Structure of the Caja del Rio Plateau, New Mexico

NASA Astrophysics Data System (ADS)

Layton, M. E.; Speed, C.; Shukla, M.; Vila, A.; Chon, E.; Kitamikado, C.; Feucht, D. W.; Bedrosian, P.; Pellerin, L.

2016-12-01

Magnetotelluric (MT) and transient electromagnetic (TEM) data were acquired by students from the Summer of Applied Geophysical Experience (SAGE) to construct structural models in and around the Caja del Rio Plateau, New Mexico. The Caja del Rio is located on the La Bajada-Jemez constriction that separates the Española and Santa Domingo basins in the Rio Grande Rift. The Rio Grande Rift, the result of tectonic extensional forces, extends approximately north-south across northern New Mexico. MT data collected in 2016 were merged with that from previous years to make up an 11 km north line and a 16 km south line extending from the west side of the Caja Del Rio to the east off the plateau in the Old Buckman Road area. The resistivity distributions revealed in one-dimensional (1-D) and two-dimensional (2-D) inverse models show some robust features. Models of the north are interpreted as a top resistive layer (<500m) of Tertiary volcanoclastic rock, to a central conductive layer (600-200m) of Mesozoic and Paleozoic sediments of the Santa Fe group to crystalline basement rock. Models for the south line show low resistivity for the first 3 to 5 km and then transitions into higher resistivity values consistent with the models for the north line. At a period of 100 seconds induction arrows (Parkinson's convention) point in the northwest direction towards the conductive Valles Caldera. The MT models are consistent with geologic interpretations of the stratigraphic units. In addition, models disclose an additional conductive layer below the basement that we interpret as the mid-crustal conductor. Transient electromagnetic (TEM) data were collected in seven locations atop the Caja del Rio plateau in an attempt to identify the basal contact of the Cerros del Rio volcanic field, which, in turn, allow for the thickness of these basaltic and andesitic deposits to be mapped across the plateau. One-dimensional inverse models produced from the TEM data were aligned and interpreted

Late-stage magmatic to deuteric/metasomatic accessory minerals from the Cerro Boggiani agpaitic complex (Alto Paraguay Alkaline Province)

NASA Astrophysics Data System (ADS)

Comin-Chiaramonti, Piero; Renzulli, Alberto; Ridolfi, Filippo; Enrich, Gaston E. R.; Gomes, Celso B.; De Min, Angelo; Azzone, Rogério G.; Ruberti, Excelso

2016-11-01

This work describes rare accessory minerals in volcanic and subvolcanic silica-undersaturated peralkaline and agpaitic rocks from the Permo-Triassic Cerro Boggiani complex (Eastern Paraguay) in the Alto Paraguay Alkaline Province. These accessory phases consist of various minerals including Th-U oxides/silicates, Nb-oxide, REE-Sr-Ba bearing carbonates-fluorcarbonates-phosphates-silicates and Zr-Na rich silicates. They form a late-stage magmatic to deuteric/metasomatic assemblage in agpaitic nepheline syenites and phonolite dykes/lava flows made of sodalite, analcime, albite, fluorite, calcite, ilmenite-pyrophanite, titanite and zircon. It is inferred that carbonatitic fluids rich in F, Na and REE percolated into the subvolcanic system and metasomatically interacted with the Cerro Boggiani peralkaline and agpaitic silicate melts at the thermal boundary layers of the magma chamber, during and shortly after their late-stage magmatic crystallization and hydrothermal deuteric alteration.

Subsurface imaging in a sector of Cerro Prieto transform fault near to pull-apart basin, Mexicali Valley, Baja California, Mexico, based on crooked lines 2D seismic reflection.

NASA Astrophysics Data System (ADS)

Mares-Agüero, M. A.; González-Escobar, M.; Arregui, S.

2016-12-01

In the transition zone between San Andres continental transformation system and the coupled transform faults system and rifting of Gulf of California is located the Cerro Prieto pull-apart basin delimitated by Imperial fault (northeast) and Cerro Prieto fault (CPF) (southwest), this last, is the limit west of Cerro Prieto geothermic field (CPGF). Crooked lines 2D seismic reflection, covering a portion near the intersection of CPF and CPGF are processed and interpreted. The seismic data were obtained in the early 80's by Petróleos Mexicanos (PEMEX). By decades, technical and investigation works in Cerro Prieto geothermic field and its vicinity had mapped faults at several depths but do not stablish a clear limit where this faults and CPF interact due the complex hydrothermal effects imaging the subsurface. The profiles showing the presence of a zone of uplift effect due to CPF. Considering the proximity of the profiles to CPF, it is surprising almost total absence of faults. A strong reflector around 2 km of depth, it is present in all profiles. This seismic reflector is considered a layer of shale, result of the correlation with a well located in the same region.

Structural control on geothermal circulation in the Cerro Tuzgle-Tocomar geothermal volcanic area (Puna plateau, Argentina)

NASA Astrophysics Data System (ADS)

Giordano, Guido; Pinton, Annamaria; Cianfarra, Paola; Baez, Walter; Chiodi, Agostina; Viramonte, José; Norini, Gianluca; Groppelli, Gianluca

2013-01-01

The reconstruction of the stratigraphical-structural framework and the hydrogeology of geothermal areas is fundamental for understanding the relationships between cap rocks, reservoir and circulation of geothermal fluids and for planning the exploitation of the field. The Cerro Tuzgle-Tocomar geothermal volcanic area (Puna plateau, Central Andes, NW Argentina) has a high geothermal potential. It is crossed by the active NW-SE trans-Andean tectonic lineament known as the Calama-Olacapato-Toro (COT) fault system, which favours a high secondary permeability testified by the presence of numerous springs. This study presents new stratigraphic and hydrogeological data on the geothermal field, together with the analysis from remote sensed image analysis of morphostructural evidences associated with the structural framework and active tectonics. Our data suggest that the main geothermal reservoir is located within or below the Pre-Palaeozoic-Ordovician basement units, characterised by unevenly distributed secondary permeability. The reservoir is recharged by infiltration in the ridges above 4500 m a.s.l., where basement rocks are in outcrop. Below 4500 m a.s.l., the reservoir is covered by the low permeable Miocene-Quaternary units that allow a poor circulation of shallow groundwater. Geothermal fluids upwell in areas with more intense fracturing, especially where main regional structures, particularly NW-SE COT-parallel lineaments, intersect with secondary structures, such as at the Tocomar field. Away from the main tectonic features, such as at the Cerro Tuzgle field, the less developed network of faults and fractures allows only a moderate upwelling of geothermal fluids and a mixing between hot and shallow cold waters. The integration of field-based and remote-sensing analyses at the Cerro Tuzgle-Tocomar area proved to be effective in approaching the prospection of remote geothermal fields, and in defining the conceptual model for geothermal circulation.

Volcano-ice-sea interaction in the Cerro Santa Marta area, northwest James Ross Island, Antarctic Peninsula

NASA Astrophysics Data System (ADS)

Calabozo, Fernando M.; Strelin, Jorge A.; Orihashi, Yuji; Sumino, Hirochika; Keller, Randall A.

2015-05-01

We present here the results of detailed mapping, lithofacies analysis and stratigraphy of the Neogene James Ross Island Volcanic Group (Antarctic Peninsula) in the Cerro Santa Marta area (northwest of James Ross Island), in order to give constraints on the evolution of a glaciated volcanic island. Our field results included recognition and interpretation of seventeen volcanic and glacial lithofacies, together with their vertical and lateral arrangements, supported by four new unspiked K-Ar ages. This allowed us to conclude that the construction of the volcanic pile in this area took place during two main eruptive stages (Eruptive Stages 1 and 2), separated from the Cretaceous bedrock and from each other by two major glacial unconformities (U1 and U2). The U1 unconformity is related to Antarctic Peninsula Ice sheet expansion during the late Miocene (before 6.2 Ma) and deposition of glacial lithofacies in a glaciomarine setting. Following this glacial advance, Eruptive Stage 1 (6.2-4.6 Ma) volcanism started with subaerial extrusion of lava flows from an unrecognized vent north of the study area, with eruptions later fed from vent/s centered at Cerro Santa Marta volcano, where cinder cone deposits and a volcanic conduit/lava lake are preserved. These lava flows fed an extensive (> 7 km long) hyaloclastite delta system that was probably emplaced in a shallow marine environment. A second unconformity (U2) was related to expansion of a local ice cap, centered on James Ross Island, which truncated all the eruptive units of Eruptive Stage 1. Concomitant with glacier advance, renewed volcanic activity (Eruptive Stage 2) started after 4.6 Ma and volcanic products were fed again by Cerro Santa Marta vents. We infer that glaciovolcanic eruptions occurred under a moderately thin (~ 300 m) glacier, in good agreement with previous estimates of paleo-ice thickness for the James Ross Island area during the Pliocene.

Textural Variations during Antigorite Dehydration as Markers for Fluid Release Mechanisms in Subduction Zones: Constrains from the Cerro del Almirez Ultramafic Massif (Betic Cordillera, SE Spain)

NASA Astrophysics Data System (ADS)

Dilissen, N. M.; Garrido, C. J.; Lopez Sanchez-Vizcaino, V.; Jabaloy-Sánchez, A.; Padrón-Navarta, J. A.

2015-12-01

Subduction zones are dynamic convergent plate boundaries associated with arc volcanism and earthquakes, which are believed to be controlled by fluids released during devolatilization reactions from the downgoing slab. The high-pressure breakdown of antigorite serpentinite to prograde chlorite-harzburgite is considered to be the most significant source of water in subduction zones. The Cerro del Almirez ultramafic massif (Betic Cordillera, SE Spain) is a unique exhumed subduction terrane that preserves this dehydration reaction as a sharp front. Chl-harzburgite in this massif displays two differentiated textures-granofels and spinifex-like- indicating that antigorite breakdown occurred at different overstepping of the dehydration reaction. Detailed mapping of textural variations in chl-harzburgite unveils a network of granofels and spinifex-like lenses. These lenses have triaxial ellipsoid shapes with average axial ratios of 16:7:1 and 19:8:1, respectively, with the shorter axis nearly perpendicular to the serpentine-out isograd, and the longest axis ranging from 23 to 190 meters. We calculated the volume of water release per lens using the modal amount of olivine according to the model reaction 1Atg = 4Clin + 6Fo + 6En + 15H2O. The growth time and water flux per lens was computed using experimental olivine growth rates for granular and dendritic, spinifex-like olivine. Preliminary results show that formation of spinifex and granofels lenses imply temporal variations of the volumetric water fluxes ranging from 0.12 to 0.02 m3m-2yr-1, respectively. If the time of formation of lenses is inversely proportional to its relative distance to the dehydration front, the 52m thick, chl-harzburgite lens network in Almirez records ca. 315 yrs of antigorite dehydration. Our results show that antigorite dehydration in subduction zones occurs in a highly non-steady regime with yearly to decadal variations of water fluxes that record variations in the dynamics of slab and fluid

Velocidades radiales Coravel y fotometría UBV de gigantes rojas del cúmulo abierto Melotte71

NASA Astrophysics Data System (ADS)

Mermilliod, J. C.; Clariá, J. J.; Andersen, J.; Mayor, M.

Se presentan velocidades radiales determinadas con el espectrovelocímetro CORAVEL y fotometría UBV de 24 gigantes rojas del cúmulo abierto de edad-intermedia Melotte71. Las observaciones realizadas en La Silla y Cerro Tololo permiten confirmar la pertenencia al cúmulo de 16 estrellas, de las cuales 8 constituyen nuevas binarias espectroscópicas cuyos períodos oscilan entre 74 y 1627 días. La velocidad radial media es +57.17 ± 0.47 km/s. El mejor ajuste con una isócrona teórica se obtiene para log t (edad) = 9.00 y Z = 0.008, no obstante existir algunas discrepancias respecto de la ubicación predicha y observada del ``clump".

Engaging communities in post-fire restoration: forest treatments and community-agency relations after the Cerro Grande fire

Treesearch

Robert L. Ryan; Elisabeth M. Hamin

2006-01-01

Our research provides advice to managers in their work in post-fire forest rehabilitation based on focus groups and interviews in the Los Alamos, New Mexico, community after the Cerro Grande fire of 2000. We address two key issues: how different restoration efforts compare to natural revegetation from the public?s perspective, and how to effectively communicate with...

Examination of the home destruction in Los Alamos associated with the Cerro Grande Fire - July 10, 2000

Treesearch

Jack D. Cohen

2000-01-01

I arrived at Los Alamos on May 14, 2000 to conduct an examination of the home destruction associated with the Cerro Grande Fire. My examination occurred between the afternoon of 5/14 and late afternoon on 5/16. I had contact with the southern command post incident management team, the Los Alamos Fire Department, and the Santa Fe National Forest.The...

12. Photocopy of drawing (this photograph is an 8' x ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Photocopy of drawing (this photograph is an 8' x 10' contact print; May 12, 1982 revision of a January 18, 1974 as built drawing by F. Marquez Ramos, in possesion of the Bridge Evaluation Office of the Puerto Rico Department of Transportation and Public Works) BRIDE (sic) OVER RIO GRANDE DE LOIZA, ROAD NO. 980 KM. 10.6 - Puente de la Marina, San Lorenzo-Florida & Cerro Gordo Neighborhoods, spanning Rio Grande de Loiza River at Narciso Varona-Suarez Street, San Lorenzo, San Lorenzo Municipio, PR

Cerros del Norte Conservation Act

THOMAS, 113th Congress

Sen. Udall, Tom [D-NM

2013-02-07

Senate - 06/27/2013 Placed on Senate Legislative Calendar under General Orders. Calendar No. 108. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Performance of casings in Cerro Prieto production wells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dominguez A, B.; Vital B, F.; Bermejo M, F.

A careful evaluation of different production casings used at Cerro Prieto from 1964 to date has shown that the following casings have yielded particularly impressive results: 7 5/8-in. diameter, J-55, 26 lb/ft; 7 5/8-in. diameter, K-55, 45.3 lb/ft; and 5-in. diameter, K-55, 23.2 lb/ft. These casings differ from others of the same diameter but lighter weight which were also used at the field. The results are favorable in spite of severe construction problems, especially the loss of circulation during cementing operations, which we encountered in some of the wells where these casings were used. The use of gravity-fed fine sandmore » as packing material and the arrangement of the production and intermediate casings were important in avoiding damage due to tension-compression stresses and, above all, damage due to internal or external corrosion over time. This situation is clearly evidenced if we compare the damage to the above casings with that experienced by grade N-80 production casings, especially in a corrosive environment.« less

Trace Element Geochemistry of Silica Phases: Understanding the Evolution of the Cerro Pabellón Geothermal System

NASA Astrophysics Data System (ADS)

Alvear, B.; Morata, D.; Leisen, M.; Reich, M.; Barra, F.

2017-12-01

The study of mineral textures coupled with trace element geochemistry has proven to be a useful tool to understand the evolution of geological environments. The purpose of this study is to provide new constrains on the formation of an active geothermal system, specifically the Cerro Pabellón field. The Cerro Pabellón system is located at 4500 m above sea level and is the first geothermal power plant in operation in Chile and South America. Thirteen samples were collected from a 550 m long drill core. Samples were first studied under petrographic microscopy followed by scanning electron microscopy coupled with a cathodoluminescence detector (CL-SEM). The different textures recognized using petrography and the CL-SEM technique were later analyzed by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) in order to determine variations in the trace element concentrations as a function of silica textures. Two vein types (A and B) with different silica polymorphs were identified by CL-SEM. Vein type A has only a colloform texture, whereas vein type B, younger and crosscutting the type A, shows zonation, colloform, and jigsaw textures. LA-ICPMS results show high concentrations of Li, Al, Na, K, As, and Sb for all types of silica. A comparison between vein type A and B, show that vein type A is Al-Na-K-Li poor (2088, 36, 309, and 122 ppm average, respectively) and As-Sb rich (43 and 249 ppm average, respectively). On the other hand, vein type B has variable concentrations of Al-Na-K-Li-Sb, but usually higher than in vein type A. Overall, the Cerro Pabellón geothermal system shows high concentrations of Li and Sb, reaching up to 360 and 703 ppm, respectively. Our preliminary results show that the trace element geochemistry is strongly related to the different silica textures, which formed as a response to different thermodynamic conditions and fluid-rock ratios. This work is a contribution to the FONDAP-CONICYT 15090013 Project.

The age and constitution of Cerro Campanario, a mafic stratovolcano in the Andes of central Chile

USGS Publications Warehouse

Hildreth, W.; Singer, B.; Godoy, E.; Munizaga, F.

1998-01-01

Cerro Campanario, a towering landmark on the continental divide near Paso Pehuenche, is a glacially eroded remnant of a mafic stratovolcano that is much younger than previously supposed. Consisting of fairly uniform basaltic andesite, rich in olivine and plagioclase, the 10-15 km3 edifice grew rapidly near the end of the middle Pleistocene, about 150-160 ka, as indicated by 40Ar/39Ar and unspiked K-Ar analyses of its lavas.

Experimental and petrological constraints on long-term magma dynamics and post-climactic eruptions at the Cerro Galán caldera system, NW Argentina

NASA Astrophysics Data System (ADS)

Grocke, Stephanie B.; Andrews, Benjamin J.; de Silva, Shanaka L.

2017-11-01

Cerro Galán in NW Argentina records > 3.5 Myr of magmatic evolution of a major resurgent caldera complex. Beginning at 5.72 Ma, nine rhyodacitic ignimbrites (68-71 wt% SiO2) with a combined minimum volume of > 1200 km3 (Dense Rock Equivalent; DRE) have been erupted. The youngest of those ignimbrites is the eponymous, geochemically homogenous, caldera-forming 2.08 ± 0.02 Ma Cerro Galán Ignimbrite (CGI; > 630 km3 DRE). Following this climactic supereruption, structural and magmatic resurgence led to the formation of a resurgent dome and post-climactic lava domes and their associated pyroclastic deposits. A clear transition from amphibole to sanidine-bearing magmas occurred during the evolution of Cerro Galán and is inferred to represent a shallowing of the magma system. We test this hypothesis here using experimental phase equilibria. We conducted a series of phase equilibria experiments on the post-climactic dome lithologies under H2O-saturated conditions using cold seal Waspaloy pressure vessels with an intrinsic log fO2 of NNO + 1 ± 0.5 across a temperature-pressure range of 750-900 °C and 50-200 MPa (PH2O = Ptotal), respectively. Petrologic and geochemical analysis of the post-climactic lithologies shows that the natural phase assemblage (plagioclase + quartz + biotite + sanidine + Fe-Ti oxides ± apatite ± zircon) is stable at < 50 MPa (PH2O) and 805-815 °C. Applying experimental results to the CGI pumice, which has the same phenocryst phase assemblage and modal abundance, whole rock and phenocryst chemistry, and overlapping temperature and fO2 as the post-climactic deposits, suggests that these pre-eruptive conditions (PH2O < 50 MPa) are relevant for the magmas that sourced the climactic CGI supereruption as well. Amphibole in the early Cerro Galán ignimbrites (Toconquis Group; 5.72-4.51 Ma, and the Cueva Negra Ignimbrite, 3.77 ± 0.08 Ma) records crystallization across a range of pressures (500 to 200 ± 60 MPa). In the interval between the eruption

[Reptiles from Cerro Colorado and its surroundings, Cumana, Sucre State, Venezuela].

PubMed

Oliveros, O; Prieto, A; Comejo, P

2000-01-01

An inventory of the reptiles that inhabit in Cerro Colorado and its surroundings, was performed from March, 1994 to March, 1995. There were reported 8 species of snakes and 7 of lizards enclosed in 4 and 5 families repectively. Aspects observed were ecolology as habitat, activity, reproduction and relative abundance. The more abundant species of lizards were: Cnemidophorus femniscatus, Ameiva bifrontata, (Teiidae), Tropidurus hispidus (Tropiduridae), Gonatodes vittatus and Hemidactylus mabouia (Gekkonidae) and the ophidians: Leptodeira annulata and Mastigodryas amarali (Colubridae). It is believed that the changes occurred in the zone influenced the increase of the relative abundance of the species Leptotyphlops goudotii (Leptotyphlopidae) arid Gymnophthalmus speciosus(Gymnophthalmidae) and perhaps in the disappearance of others that have been reported at the xerophitic or semixerophitic zones of the Sucre State of Venezuela.

3D gravimetric investigation of the Cerro do Jarau structure, Rio Grande do Sul, Brazil

NASA Astrophysics Data System (ADS)

Giacomini, Bruno B.; Leite, Emilson P.; Crósta, Alvaro P.

2017-04-01

The Cerro do Jarau structure is possibly the third Brazilian basaltic crater formed in continental flood basalt of the Serra Geral Formation, Paraná Basin, a large igneous province (LIP) in southern Brazil. It is a nearly circular landform with a diameter of approximately 13 km that rises 200 m above the plains of the "pampas" in southern Brazil. In this work, Bouguer anomalies were calculated from gravity accelerations measured on the area of this structure. The residual Bouguer map shows a strong positive anomaly trending NE-SW, located in the northeastern part of the structure, a feature not commonly associated with impact structures. However, the negative anomaly present in its center and the circular positive anomaly surrounding the central portion are typical of impact structures. The residual Bouguer anomaly varies from -2 mGal to 8 mGal. The positive circular anomaly is not spatially coincident with the rim of the structure. Based on the interpretation of our gravimetric data, the estimated diameter of the structure is 12 km and the central portion has a diameter of approximately 5 km, both slightly smaller than previously suggested. The Bouguer anomaly map was inverted into a 3D density model using a constrained inversion method with a maximum density contrast of 0.5 g cm-3. This model was interpreted to associate densities with rock types, resulting in a geological model. This geological model is in accordance with the meteorite impact nature of Cerro do Jarau.

Downwelling Far-Infrared Emission Spectra Measured By First at Cerro Toco, Chile and Table Mountain, California

NASA Astrophysics Data System (ADS)

Mast, J. C.; Mlynczak, M. G.; Cageao, R.; Kratz, D. P.; Johnson, D. G.; Mlawer, E. J.; Turner, D. D.

2014-12-01

The Far-Infrared Spectroscopy of the Troposphere (FIRST) instrument is a Fourier transform spectrometer developed to measure the important far-infrared spectrum between 100 and 650 cm-1. Presented here are measurements made by FIRST during two successful deployments in a ground-based configuration to measure downwelling longwave radiation at Earth's surface. The initial deployment was to Cerro Toco, Chile, where FIRST operated from August to October, 2009 as part of the Radiative Heating in Underexplored Bands Campaign (RHUBC-II) campaign. After recalibration, FIRST was deployed to the Table Mountain Facility from September through October, 2012. Spectra observed at each location are substantially different, due in large part to the order of magnitude difference in integrated precipitable water vapor (0.3 cm at Table Mountain, 0.03 cm at Cerro Toco). Dry days for both campaigns are chosen for analysis - 09/24/2009 and 10/19/2012. Also available during both deployments are coincident radiosonde temperature and water vapor vertical profiles which are used as inputs a line-by-line radiative transfer program. Comparisons between measured and modeled spectra are presented over the 200 to 800 cm-1 range. An extensive error analysis of both the measured and modeled spectra is presented. In general, the differences between the measured and modeled spectra are within their combined uncertainties.

A re-appraisal of the stratigraphy and volcanology of the Cerro Galán volcanic system, NW Argentina

USGS Publications Warehouse

Folkes, Christopher B.; Wright, Heather M.; Cas, Ray A.F.; de Silva, Shanaka L.; Lesti, Chiara; Viramonte, Jose G.

2011-01-01

From detailed fieldwork and biotite 40Ar/39Ar dating correlated with paleomagnetic analyses of lithic clasts, we present a revision of the stratigraphy, areal extent and volume estimates of ignimbrites in the Cerro Galán volcanic complex. We find evidence for nine distinct outflow ignimbrites, including two newly identified ignimbrites in the Toconquis Group (the Pitas and Vega Ignimbrites). Toconquis Group Ignimbrites (~5.60–4.51 Ma biotite ages) have been discovered to the southwest and north of the caldera, increasing their spatial extents from previous estimates. Previously thought to be contemporaneous, we distinguish the Real Grande Ignimbrite (4.68 ± 0.07 Ma biotite age) from the Cueva Negra Ignimbrite (3.77 ± 0.08 Ma biotite age). The form and collapse processes of the Cerro Galán caldera are also reassessed. Based on re-interpretation of the margins of the caldera, we find evidence for a fault-bounded trapdoor collapse hinged along a regional N-S fault on the eastern side of the caldera and accommodated on a N-S fault on the western caldera margin. The collapsed area defines a roughly isosceles trapezoid shape elongated E-W and with maximum dimensions 27 × 16 km. The Cerro Galán Ignimbrite (CGI; 2.08 ± 0.02 Ma sanidine age) outflow sheet extends to 40 km in all directions from the inferred structural margins, with a maximum runout distance of ~80 km to the north of the caldera. New deposit volume estimates confirm an increase in eruptive volume through time, wherein the Toconquis Group Ignimbrites increase in volume from the ~10 km3 Lower Merihuaca Ignimbrite to a maximum of ~390 km3 (Dense Rock Equivalent; DRE) with the Real Grande Ignimbrite. The climactic CGI has a revised volume of ~630 km3 (DRE), approximately two thirds of the commonly quoted value.

Sulphur-Rich Melt At Upper Crustal Levels At Cerro La Torta, Central Andes: Evidence From Melt Inclusions Assemblages.

NASA Astrophysics Data System (ADS)

Cannatelli, C.; Godoy, B.; Alvear, B.; Moncada, D.

2016-12-01

Central Andes present some of the biggest and most important porphyry copper ore deposits in the world. Porphyry copper ore formation is related to precipitation of ore minerals from sulphur and chlorine-rich fluids. Genesis of these deposits occurred 4 km below surface, while mineralized fluids are released by magmatic melts located between 5 and 15 km depth (Sillitoe, 2010). Cerro La Torta is part of a cluster of <105 ka rhyodacitic domes related to the waning stage of the Altiplano-Puna Volcanic Complex at Central Andes (Tierney et al., 2016). These domes reflect a crystal-rich mush layer at the upper crust - named Altiplano-Puna Magma Body (APMB) - which is proposed to be a voluminous partially molten body locate at shallow depth (4-25 km), with a thickness up to 11 km (Ward et al., 2014). Cerro La Torta is a crystal-rich ( 40% vol.) dacitic flow with plagioclase, amphibole, biotite, and quartz phenocrysts on a glassy (up to 50% vol.) groundmass. During detailed petrographic observation, two types of Melt Inclusions Assemblages (MIAs) were observed in the plagioclase. Group I is found in the core of crystals, and contains sulphide, pyrite ± bubbles. Group II of bubble-bearing MIAs is observed at the rim of the phenocrysts, with no associated sulphide mineral present. Melt Inclusions size ranges from 10-40 µm, suggesting an intermediate cooling rate (Roedder 1979). Out hypothesis is that during cooling, Group I MIA is trapped as result of a metal sulfur-rich event, leading to the suggestion that sulphide-bearing MIAs from Cerro La Torta are the evidence of mineralized magmas ponding at shallow crustal levels. Furthermore, the presence of MIAs in the mush-type magmas related to the APMB implies that such systems are suitable to porphyry copper ore generation. Roedder, 1979. The Evolution of the Igneous Rocks. 15-57 Sillitoe, 2010. Econ. Geol. 105:3-41 Tierney et al., 2016. Geology 44:683-686. doi:10.1130/G37968.1Ward et al., 2014. Earth Planet Sci Letters 404:43-54

An integrated model for the natural flow regime in the Cerro Prieto hydrothermal system based upon petrological and isotope geochemical criteria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elders, W.A.; Williams, A.E.; Hoagland, J..

1981-01-01

Studies of cuttings and cores at Cerro Prieto have now been extended to more than 50 boreholes. The aims of this petrological and isotopic work are to determine the shape of the reservoir, its physical properties, and its temperature distribution and flow regime before the steam field was produced.

Detailed microearthquake studies at the Cerro Prieto geothermal field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Majer, E.L.; McEvilly, T.V.

There appears to be an increase in seismic activity within the Cerro Prieto production zone since early 1978. The microearthquake activity is now more or less constant at a rate of 2 to 3 events per day. The b-values within the field are significantly higher inside the production zone than are those for events on faults outside of the production region. The earthquakes seem to be controlled by the Hidalgo fault, although slight clustering was observed in the center of the main production region. The earthquakes within the production zone may reflect the reservoir dynamics associated with heat and massmore » withdrawal. Mechanisms such as volume change, thermal stresses and weakening of materials associated with boiling (i.e., phase changes, dissolution) may all be responsible for the increased seismic activity. Although a small reinjection program has started, the pressure drawdown conditions existing within the field would imply that increased pore pressure resulting from the injection activities is not responsible for the increased seismic activity.« less

Geochemical homogeneity of a long-lived, large silicic system; evidence from the Cerro Galán caldera, NW Argentina

NASA Astrophysics Data System (ADS)

Folkes, Chris B.; de Silva, Shanaka L.; Wright, Heather M.; Cas, Raymond A. F.

2011-12-01

By applying a number of analytical techniques across a spectrum of spatial scales (centimeter to micrometer) in juvenile components, we show that the Cerro Galán volcanic system has repeatedly erupted magmas with nearly identical geochemistries over >3.5 Myr. The Cerro Galán system produced nine ignimbrites (˜5.6 to 2 Ma) with a cumulative volume of >1,200 km3 (DRE; dense rock equivalent) of calc-alkaline, high-K rhyodacitic magmas (68-71 wt.% SiO2). The mineralogy is broadly constant throughout the eruptive sequence, comprising plagioclase, quartz, biotite, Fe-Ti oxides, apatite, and titanite. Early ignimbrite magmas also contained amphibole, while the final eruption, the most voluminous Cerro Galán ignimbrite (CGI; 2.08 ± 0.02 Ma) erupted a magma containing rare amphibole, but significant sanidine. Each ignimbrite contains two main juvenile clast types; dominant "white" pumice and ubiquitous but subordinate "grey" pumice. Fe-Ti oxide and amphibole-plagioclase thermometry coupled with amphibole barometry suggest that the grey pumice originated from potentially hotter and deeper magmas (800-840°C, 3-5 kbar) than the more voluminous white pumice (770-810°C, 1.5-2.5 kbar). The grey pumice is interpreted to represent the parental magmas to the Galán system emplaced into the upper crust from a deeper storage zone. Most inter-ignimbrite variations can be accounted for by differences in modal mineralogy and crystal contents that vary from 40 to 55 vol.% on a vesicle-free basis. Geochemical modeling shows that subtle bulk-rock variations in Ta, Y, Nb, Dy, and Yb between the Galán ignimbrites can be reconciled with differences in amounts of crystal fractionation from the "grey" parent magma. The amount of fractionation is inversely correlated with volume; the CGI (˜630 km3) and Real Grande Ignimbrite (˜390 km3) return higher F values (proportion of liquid remaining) than the older Toconquis Group ignimbrites (<50 km3), implying less crystal fractionation took

Changing fluvial styles in volcaniclastic successions: A cretaceous example from the Cerro Barcino Formation, Patagonia

NASA Astrophysics Data System (ADS)

Umazano, A. Martín; Krause, J. Marcelo; Bellosi, Eduardo S.; Perez, Mariano; Visconti, Graciela; Melchor, Ricardo N.

2017-08-01

The Cretaceous Puesto La Paloma (PLPM) and Cerro Castaño (CCM) members (Cerro Barcino Formation, Chubut Group) are pyroclastic-rich, alluvial successions deposited in the Somuncurá-Cañadón Asfalto Basin during sag and endorheic conditions. The PLPM comprises sheet-like tuffaceous sandstone strata, whereas the overlying CCM includes sheet-to ribbon-channel sandstone bodies intercalated within tuffaceous and fine-grained sediments. In this context, the goals of this contribution were: i) to make a detailed documentation of the contrasting sedimentary palaeonvironments; and ii) to infer the allocyclic controls that governed the sedimentation of both units. The study area is located in the western sector of the basin, where six localities, which were studied. Six facies associations were defined including ash-falls, sheet-floods, shallow lakes, aeolian, fluvial channel-belts, and reworked debris-flows. We defined four stratigraphic intervals for the studied sections, denominated 1 to 4 in chronological order of deposition, which increase their thicknesses toward the Puesto Mesa-Cerro León site. The interval 1 (18-42 m thick) corresponds to the PLPM and includes numerous pedogenized sheet-flood deposits, carbonate-rich lacustrine, aeolian sandy facies, and ash-fall beds. The interval 1 is interpreted as an ephemeral and unconfined alluvial system that interacted with aeolian dunes and dry interdune zones. The interval 2 (20-47 m thick) represents the lower part of the CCM. It shows an alternation of fluvial channel-belt deposits and vegetated floodplain facies with sediments originated from sheet-floods, lakes, and few ash-falls and debris-flows. The mean palaeoflow was toward E-SE, except in the northernmost locality where the drainage was towards SW. Proportion of channel-belt bodies ranges from 10 to 36%, reaching higher values in the northern part of the study area, where they are also thicker. The interval 2 represents a permanent, meandering or locally low

Cerro Negro, Nicaragua: A key Mars Analog Environment for Acid-Sulfate Weathering

NASA Astrophysics Data System (ADS)

Hynek, B. M.; Rogers, K. L.; McCollom, T. M.

2008-12-01

Sulfate-rich bedrock has been discovered in many locations on Mars and has been studied by both orbiting spacecraft and landers. It appears that in most cases these minerals are produced by acid-sulfate weathering of igneous rocks, which may have been a widespread process for the first billion years of Mars' history. The origin of life on Earth may have occurred in iron-sulfur hydrothermal settings and it is conceivable that early Mars had similar environmental conditions. An excellent terrestrial analog for acid- sulfate weathering of Mars-like basalts exists at Cerro Negro (CN), Nicaragua, where sulfur-bearing gases interact with recently erupted basaltic ash in numerous fumaroles. To date, we have made two expeditions to CN to assess the chemical, mineralogical, and biological conditions. At the fumaroles pH ranges from <1 to 5 and temperatures range from 40 to 400° C. Basalts with a chemical composition very similar to those on Mars are being chemically altered in the solfatara setting. In a few years, freshly erupted basalt can be converted into predominately Ca-, Mg-, and Fe-sulfates, Fe-hydroxides (including jarosite), clays, and free silica. Altered rocks have up to 30 wt% SO3 equivalent, which is similar to the Meridiani Planum bedrocks and inferred in other sulfate-bearing bedrock on Mars. Moreover, heavily weathered rocks have silica contents up to 80 wt%, similar to silica-rich soils at Gusev Crater that possibly formed in hydrothermal environments. Samples were collected for biological analysis including enrichment and isolation of novel thermophiles as well as molecular characterization of thermophile diversity. The low water and nutrient levels found in solfatara environments lead to less biomass when compared to hot springs with similar geochemical conditions. Nonetheless, microbes are thriving in these hot, acidic vent environments. At Cerro Negro solfatara, we are characterizing the metabolic and phylogenetic diversity of resident microbial

Volcanic hazard map for Telica, Cerro Negro and El Hoyo volcanoes, Nicaragua

NASA Astrophysics Data System (ADS)

Asahina, T.; Navarro, M.; Strauch, W.

2007-05-01

A volcano hazard study was conducted for Telica, Cerro Negro and El Hoyo volcanoes, Nicaragua, based on geological and volcanological field investigations, air photo analyses, and numerical eruption simulation. These volcanoes are among the most active volcanoes of the country. This study was realized 2004-2006 through technical cooperation of Japan International Cooperation Agency (JICA) with INETER, upon the request of the Government of Nicaragua. The resulting volcanic hazard map on 1:50,000 scale displays the hazards of lava flow, pyroclastic flows, lahars, tephra fall, volcanic bombs for an area of 1,300 square kilometers. The map and corresponding GIS coverage was handed out to Central, Departmental and Municipal authorities for their use and is included in a National GIS on Georisks developed and maintained by INETER.

Photosynthesis within Mars' volcanic craters?: Insights from Cerro Negro Volcano, Nicaragua

NASA Astrophysics Data System (ADS)

Rogers, K. L.; Hynek, B. M.; McCollom, T. M.

2011-12-01

Discrete locales of sulfate-rich bedrocks exist on Mars and in many cases represent the products of acid-sulfate alteration of martian basalt. In some places, the products have been attributed to hydrothermal processes from local volcanism. In order to evaluate the habitability of such an environment, we are investigating the geochemical and biological composition of active fumaroles at Cerro Negro Volcano, Nicaragua, where fresh basaltic cinders similar in composition to martian basalts are altered by acidic, sulfur-bearing gases. Temperatures at active fumaroles can reach as high as 400°C and the pH of the steam ranges from <0 to 5. Adjacent to some fumaroles, silica is being precipitated from condensing steam on the crater walls and endolithic photosynthetic mats are found at 1-2 cm depth within these silica deposits. We have analyzed one of these mats, Monkey Cheek (T=65°C, pH ~4.5), for both Archaeal and Bacterial diversity. Cloning of PCR-amplified 16S rRNA genes reveals a diverse community of Bacteria, with eight phyla represented. The most common bacterial sequences belonged to the Cyanobacteria and Ktedonobacteria, however Actinobacteria, alpha-Proteobacteria and Acidobacteria were also identified. Many of the cyanobacterial sequences were similar to those of the eukaryotic Cyanidiales, red algae that inhabit acidic, geothermal environments. Many of sequences related to Ktedonobacteria and Actinobacteria have also been found in acid mine drainage environments. The Archaeal community was far less diverse, with sequences matching those of unclassified Desulfurococcales and unclassified Thermoprotei. These sequences were more distant from isolated species than the bacterial sequences. Similar bacterial and archaeal communities have been found in hot spring environments in Yellowstone National Park, Greenland, Iceland, New Zealand and Costa Rica. Some of Mars' volcanoes were active for billions of years and by analogy to Cerro Negro, may have hosted

High-resolution carbonate isotopic study of the Mural Formation (Cerro Pimas section), Sonora, México: Implications for early Albian oceanic anoxic events

NASA Astrophysics Data System (ADS)

Madhavaraju, J.; Lee, Yong Il; Scott, R. W.; González-León, C. M.; Jenkyns, H. C.; Saucedo-Samaniego, J. C.; Ramasamy, S.

2018-03-01

The 420-m thick stratigraphic section of the Mural Formation that is exposed in the Cerro Pimas area of northern Sonora, Mexico, is composed of limestone lithofacies ranging from bioclastic wackestone to boundstone, whose biota is characterized by low diversity. Prominent age-diagnostic fossils are benthic foraminifera and long-ranging calcareous algae that indicate the Aptian/Albian boundary is close to the base of the Los Coyotes Member. The carbonates of this formation have negative to positive δ13C values (-4.63 to +2.6‰) and highly depleted δ18O values that range from -12.74 to -8.34‰. The absence of correlation between δ13C and δ18O values supports a primary marine origin for the δ13C values of these limestones. The carbon-isotopic curve of the Cerro Pimas stratigraphic section has well-defined δ13C segments (C8 - C15) that compare with published curves of similar age. In the lower part of the early Albian Los Coyotes Member, the presence of OAE 1b is indicated by an increase followed by a decrease in δ13C values, suggesting correlation with the Kilian Event. The middle part of the Los Coyotes Member has a significant negative carbon-isotope excursion correlated with the globally recognizable early Albian Paquier event. Moreover, another significant negative carbon-isotope shift is observed in the upper part of the Los Coyotes Member, which can be correlated with the Leenhardt Event. The occurrence of the Kilian, Paquier and Leenhardt Events (OAE 1b cluster) in the Cerro Pimas stratigraphy confirms the global nature of these early Albian disturbances of the carbon cycle.

Radon and ammonia transects across the Cerro Prieto geothermal field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Semprini, L.; Kruger, P.

1981-01-01

Radon and ammonia transects, conducted at the Cerro Prieto geothermal field, involve measurement of concentration gradients at wells along lines of structural significance in the reservoir. Analysis of four transects showed radon concentrations ranging from 0.20 to 3.60 nCi/kg and ammonia concentrations from 17.6 to 59.3 mg/l. The data showed the lower concentrations in wells of lowest enthalpy fluid and the higher concentrations in wells of highest enthalpy fluid. Linear correlation analysis of the radon-enthalpy data indicated a strong relationship, with a marked influence by the two-phase conditions of the produced fluid. It appears that after phase separation in themore » reservoir, radon achieves radioactive equilibrium between fluid and rock, suggesting that the phase separation occurs well within the reservoir. A two-phase mixing model based on radon-enthalpy relations allows estimation of the fluid phase temperatures in the reservoir. Correlations of ammonia concentration with fluid enthalpy suggests an equilibrium partitioning model in which enrichment of ammonia correlates with higher enthalpy vapor.« less

Mathematical Modeling of the Dynamics of Salmonella Cerro Infection in a US Dairy Herd

NASA Astrophysics Data System (ADS)

Chapagain, Prem; van Kessel, Jo Ann; Karns, Jeffrey; Wolfgang, David; Schukken, Ynte; Grohn, Yrjo

2006-03-01

Salmonellosis has been one of the major causes of human foodborne illness in the US. The high prevalence of infections makes transmission dynamics of Salmonella in a farm environment of interest both from animal and human health perspectives. Mathematical modeling approaches are increasingly being applied to understand the dynamics of various infectious diseases in dairy herds. Here, we describe the transmission dynamics of Salmonella infection in a dairy herd with a set of non-linear differential equations. Although the infection dynamics of different serotypes of Salmonella in cattle are likely to be different, we find that a relatively simple SIR-type model can describe the observed dynamics of the Salmonella enterica serotype Cerro infection in the herd.

U-Th-Pb zircon dating of the 13.8-Ma dacite volcanic dome at Cerro Rico de Potosi, Bolivia

USGS Publications Warehouse

Zartman, R.E.; Cunningham, C.G.

1995-01-01

The temporal relationship between the extrusion of the Miocene dacite volcanic dome at Cerro Rico de Potasi, Bolivia, and the associated Ag-Sn mineralization has an important bearing on the heat and metal sources for this world class mineral deposit. The present study uses U-Th-Pb dating of sparse zircon contained in the dacite to demonstrate that, at most, only several hundred thousand years separate dome emplacement from main stage mineralization. -from Authors

The Cerro Tololo Inter-American Observatory Summer Student Programs in La Serena, Chile

NASA Astrophysics Data System (ADS)

Kaleida, Catherine C.; Smith, C.; Van Der Bliek, N. S.; James, D.

2014-01-01

The Cerro Tololo Inter-American Observatory (CTIO) offers positions for U.S. and Chilean student interns during the Chilean summer months of January-March (northern winter semester) at the CTIO offices in La Serena, Chile. CTIO is part of the National Optical Astronomy Observatory (NOAO) of the United States, focused on the development of astronomy in the southern hemisphere. Six undergraduate research assistantships are offered for U.S. physics and astronomy undergraduate students through the NSF-funded Research Experiences for Undergraduates (REU) program. The CTIO-funded Prácticas de Investigación en Astronomía (PIA) program is run concurrently with the REU program, and offers two research assistantships for Chilean undergraduate or 1st or 2nd year masters students, also at the CTIO offices in La Serena, Chile. The CTIO REU and PIA programs provide exceptional opportunities for students considering a career in astronomy to engage in substantive research activities with scientists working at the forefront of contemporary astrophysics. Student participants work on specific research projects in close collaboration with members of the CTIO scientific and technical staff, such as galaxy clusters, gravitational lensing, supernovae, planetary nebulae, stellar populations, star clusters, star formation, variable stars and interstellar medium. The CTIO REU and PIA programs emphasize observational techniques and provide opportunities for direct observational experience using CTIO's state-of-the-art telescopes and instrumentation. The programs run for 10 weeks, from mid-January to the end of March. A two-night observing run on Cerro Tololo and a field trip to another observatory in Chile are included for students of both programs. These positions are full time, and those selected will receive a modest stipend and subsidized housing on the grounds of the offices of CTIO in La Serena, as well as travel costs to and from La Serena. In addition, the students have the

Chihuahuan desert flora of La Calera, Municipio de Agua Prieta, Sonora, Mexico

Treesearch

Ana Lilia Reina-Guerrero; Thomas R. Van Devender

2013-01-01

A total of 555 plant collections were made on 20 trips in 2002-2008 to La Calera area in the Sierra Anibácachi, Municipio de Agua Prieta, 11.3 km south of the Arizona border (31°13’59”N 109°37’53”W, elevation range from 1220 m to 1539 m) in northeastern Sonora. Chihuahuan desertscrub on limestone substrates is dominated by creosotebush (Larrrea divaricata), Chihuahuan...

Oxygen isotope exchange in rocks and minerals from the Cerro Prieto geothermal system: Indicators of temperature distribution and fluid flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, A.E.; Elders, W.A.

1981-01-01

Oxygen isotopic compositions have been measured in drill cuttings and core samples from more than 40 wells ranging in depth to more than 3.5 km in the Cerro Prieto geothermal field. Profiles of isotopic ratios versus sampling depths provide information on the three-dimensional distribution of temperature and fluid flow. These parameters also indicate variations in the history of hydrothermal processes in different areas of the geothermal field.

The ash deposits of the 4200 BP Cerro Blanco eruption: the largest Holocene eruption of the Central Andes

NASA Astrophysics Data System (ADS)

Fernandez-Turiel, Jose-Luis; Saavedra, Julio; Perez-Torrado, Francisco-Jose; Rodriguez-Gonzalez, Alejandro; Carracedo, Juan-Carlos; Lobo, Agustin; Rejas, Marta; Gallardo, Juan-Fernando; Osterrieth, Margarita; Carrizo, Julieta; Esteban, Graciela; Martinez, Luis-Dante; Gil, Raul-Andres; Ratto, Norma; Baez, Walter

2015-04-01

We present new data about a major eruption -spreading approx. 110 km3 ashes over 440.000 km2- long thought to have occurred around 4200 years ago in the Cerro Blanco Volcanic Complex (CBVC) in the Central Andes of NW Argentina (Southern Puna, 26°45' S, 67°45' W). This eruption may be the biggest during the past five millennia in the Central Volcanic Zone of the Andes, and possibly one of the largest Holocene eruptions in the world. Discrimination and correlation of pyroclastic deposits of this eruption of Cerro Blanco was conducted comparing samples of proximal (domes, pyroclastic flow and fall deposits) with distal ash fall deposits (up to 400 km from de vent). They have been characterized using optical and electron microscopy (SEM), X-ray diffraction, particle-size distribution by laser diffraction and electron microprobe and HR-ICP-MS with laser ablation for major and trace element composition of glass, feldspars and biotite. New and published 14C ages were calibrated using Bayesian statistics. An one-at-a-time inversion method was used to reconstruct the eruption conditions using the Tephra2 code (Bonadonna et al. 2010, https://vhub.org/resources/tephra2). This method allowed setting the main features of the eruption that explains the field observations in terms of thickness and grain size distributions of the ash fall deposit. The main arguments that justify the correlation are four: 1) Compositional coincidence for glass, feldspars, and biotite in proximal and distal materials; 2) Stratigraphic and geomorphological relationships, including structure and thickness variation of the distal deposits; 3) Geochronological consistency, matching proximal and distal ages; and 4) Geographical distribution of correlated outcrops in relation to the eruption centre at the coordinates of Cerro Blanco. With a magnitude of 7.0 and a volcanic explosivity index or VEI 7, this eruption of ~4200 BP at Cerro Blanco is the largest in the last five millennia known in the Central

The age and thermal history of Cerro Rico de Potosi, Bolivia

USGS Publications Warehouse

Cunningham, C.G.; Zartman, R.E.; McKee, E.H.; Rye, R.O.; Naeser, C.W.; Sanjines, V.O.; Ericksen, G.E.; Tavera, V.F.

1996-01-01

Cerro Rico de Potosi, Bolivia, is the world's largest silver deposit and has been mined since the sixteenth century for silver, and for tin and zinc during the twentieth century, together with by-product copper and lead. The deposit consists primarily of veins that cut an altered igneous body that we interpret to be a dacitic volcanic dome and its underlying tuff ring and explosion breccia. The deposit is compositionally and thermally zoned, having a core of cassiterite, wolframite, bismuthinite, and arsenopyrite surrounded by a peripheral, lower-temperature mineral assemblage consisting principally of sphalerite, galena, lead sulfosalt, and silver minerals. The low-temperature assemblage also was superim-posed on the high-temperature assemblage in response to cooling of the main hydrothermal system. Both the dacite dome and the ore fluids were derived from a larger magmatic hydrothermal source at depth. The dome was repeatedly fractured by recurrent movement on the fault system that guided its initial emplacement. The dome was extruded at 13.8 ?? 0.2 Ma (2??), based on U-Th-Pb dating of zircon. Mineralization and alteration occurred within about 0.3 my of dome emplacement, as indicated by a 40Ar/39Ar date of 13.76 ?? 0.10 Ma (1??) for sericite from the pervasive quartz-sericite-pyrite alteration associated with the main-stage, high-temperature, mineralization. The last thermal event able to reset zircon fission tracks occurred no later than 12.5 ?? 1.1 Ma (1??). as indicated by fission-tract dating. Minor sericite. and magmatic-steam alunite veins, were episodically formed around 11 Ma and between 8.3 and 5.7 Ma; the younger episodes occurring at the time of extensional fracturing at Cerro Rico and widespread volcanism in the adjacent Los Frailes volcanic field. None of these younger events appear to be signific-ant thermal/mineralizing events: the exceptionally flat thermal release pattern of 39Ar from sericite and the results of the fission-tract dating of

Gas chemistry and thermometry of the Cerro Prieto, Mexico, geothermal field

USGS Publications Warehouse

Nehring, N.L.; D'Amore, F.

1984-01-01

Gas compositions of Cerro Prieto wells in 1977 reflected strong boiling in the reservoir around wells M-20 and M-25. This boiling zone appeared to be collapsing in 1982 when a number of wells in this area of the field were shut-in. In 1977 and 1982, gas compositions also showed boiling zones corresponding to faults H and L postulated by Halfman et al. (1982). Four gas geothermometers were applied, based on reservoir equilibria and calculated fugacities. The Fisher - Tropsch reaction predicted high temperatures and appeared to re-equilibrate slowly, whereas the H2S reaction predicted low temperatures and appeared to re-equilibrate rapidly. Hydrogen and NH3 reactions were intermediate. Like gas compositions, the geothermometers reflected reservoir processes, such as boiling. Surface gas compositions are related to well compositions, but contain large concentrations of N2 originating from air dissolved in groundwater. The groundwater appears to originate in the east and flow over the production field before mixing with reservoir gases near the surface. ?? 1984.

Configuration of the mudstones, gray- and coffee-colored shale lithologic units, zones of silica and epidote, and their relation to the tectonics of the Cerro Prieto geothermal field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cobo R, J.M.

1981-01-01

Based on well cuttings, five lithological units have been recognized within the area of what is now the Cerro Prieto geothermal field. These five units are described. Differences in origin, mineralogy, grading, color, compaction, etc., are shown.

Burning down the brewery: establishing and evacuating an ancient imperial colony at Cerro Baul, Peru.

PubMed

Moseley, Michael E; Nash, Donna J; Williams, Patrick Ryan; DeFrance, Susan D; Miranda, Ana; Ruales, Mario

2005-11-29

Before the Inca reigned, two empires held sway over the central Andes from anno Domini 600 to 1000: the Wari empire to the north ruled much of Peru, and Tiwanaku to the south reigned in Bolivia. Face-to-face contact came when both colonized the Moquegua Valley sierra in southern Peru. The state-sponsored Wari incursion, described here, entailed large-scale agrarian reclamation to sustain the occupation of two hills and the adjacent high mesa of Cerro Baúl. Monumental buildings were erected atop the mesa to serve an embassy-like delegation of nobles and attendant personnel that endured for centuries. Final evacuation of the Baúl enclave was accompanied by elaborate ceremonies with brewing, drinking, feasting, vessel smashing, and building burning.

Paleogene and Neogene magmatism in the Valle del Cura region: New perspective on the evolution of the Pampean flat slab, San Juan province, Argentina

NASA Astrophysics Data System (ADS)

Litvak, Vanesa D.; Poma, Stella; Kay, Suzanne Mahlburg

2007-09-01

The Valle del Cura region is characterized by a thick volcanic and volcaniclastic sequence that records the Tertiary arc and backarc magmatic evolution of the Argentine Main Cordillera over the modern Pampean flatslab at 29.5-30°S. During the Eocene, a retroarc basin developed, represented by the Valle del Cura Formation synorogenic volcanosedimentary sequence, which includes rhyolites and dacitic tuffs. These silicic volcanic rocks have weak arc chemical signatures and high lithophile element concentrations and are isotopically enriched relative to the late Oligocene-early Miocene volcanic rocks that followed them. Their chemical characteristics fit with eruption through a thin crust. The Valle de Cura Formation was followed by the Oligocene-early Miocene Doña Ana Group volcanic sequence, which erupted at and near the arc front west of the border with Chile. The Doña Ana Group volcanic rocks have calc-alkaline chemical characteristics consistent with parental magmas forming in a mantle wedge and erupting through a normal thickness crust (35 km). Subsequent shallowing of the downgoing Nazca plate caused the volcanic front to migrate eastward. The volcanic sequences of the middle Miocene Cerro de las Tórtolas Formation erupted at this new arc front, essentially at the Argentine border. Two stages are recognized: an older one (16-14 Ma) in which magmas appear to have erupted through a normal thickness crust (30-35 km) and a younger one (13-10 Ma) in which the steeper REE pattern suggests the magmas last equilibrated with higher pressure residual mineral assemblages in a thicker crust. Isotopic ratios in the younger group are consistent with an increase in original crustal components and crust introduced into the mantle source by forearc subduction erosion. A peak in forearc subduction erosion near 12-10 Ma is consistent with when the main part of the Juan Fernandez Ridge began to subduct beneath the region. In addition to late Miocene Tambo Formation dacitic

Geological reconnaissance of some Uruguayan iron and manganese deposits in 1962

USGS Publications Warehouse

Wallace, Roberts Manning

1976-01-01

Three mineralized areas lie in an area near the town of Minas de Corrales in the Departamento de Rivera; they are the Cerro Amelia, the Cerro de Papagayo, and the Cerro Iman. The Cerro Amelia is composed of small bands of iron-rich rock separated by an amphibolitic or mafic rock. Selective mining would be necessary to extract the 31,000 tons per meter of depth of iron-rich rock that ranges from 15 to 40 percent metallic iron. The Cerro de Papagayo district contains many small, rich deposits of ferruginous manganese ore. The ratio of Mn to Fe varies widely within each small deposit as well as from deposit to deposit. Some ferruginous manganese ore contains 50-55 percent manganese dioxide. Although there are many thousands of tons of ore in the district, small-scale mining operations are imperative. One deposit, the Cerro Avestuz manganese mine, was visited. The manganese ore body lies within contorted highly metamorphosed itabirite that contains both hard low grade and soft high grade ferruginous manganese ores estimated to average 40 percent Mn. About 38,000 tons of manganese ore is present in this deposit. The Cerro Iman is a large block of itabirite that contains about 40 percent Fe. The grade is variable and probably runs from less than 35 percent Fe to more than 50 percent Fe. No exploration has been done on this deposit. It is recommended that the Cerro de Iman area be geologically mapped in detail, and that a geological reconnaissance be made of the area that is between the Cuchilla de Corrales and the Cuchilla de Areycua/Cuchilla del Cerro Pelado area.

Intense Seismic Activity at Chiles and Cerro Negro Volcanoes on the Colombia-Ecuador Border

NASA Astrophysics Data System (ADS)

Torres, R. A.; Cadena, O.; Gomez, D.; Ruiz, M. C.; Prejean, S. G.; Lyons, J. J.; White, R. A.

2015-12-01

The region of Chiles and Cerro Negro volcanoes, located on the Colombian-Ecuadorian border, has experienced an ongoing seismic swarm beginning in Aug. 2013. Based on concern for local residents and authorities, a cooperative broadband monitoring network was installed by the Servicio Geológico Colombiano in Colombia and the Instituto Geofísico of the Escuela Politécnica Nacional in Ecuador. Since November 2013 more than 538,000 earthquakes were recorded; although since May 2015 the seismicity has decreased significantly to an average of 70 events per day. Three large earthquake swarms with increasing energy occurred in Aug.-Oct. 2013, March-May 2014, and Sept.-Dec. 2014. By the end of 2014, roughly 400 earthquakes greater than M 3 had occurred with a maximum rate of 8000 earthquakes per day. The largest earthquake was a 5.6 ML on Oct. 20, 2014. This event produced an InSAR coseismic deformation of ~23 cm (S. Ebmeier, personal communication). Most events are typical brittle failure volcano-tectonic (VT) earthquakes that are located in a cluster beneath the southern flank of Chiles volcano, with depths between 1.5 and 10 km. Although the great majority of earthquakes are VT, some low-frequency (LF, ~0.5 Hz) and very-low-frequency (VLF) events have occurred. Particle motion analysis suggests that the VLF source migrated with time. While a VLF on Oct. 15, 2014 was located south of Chiles volcano, near the InSAR source, the VLF registered on Feb. 14, 2015 was likely located very close to Chiles Volcano. We infer that magma intrusion and resulting fluid exsolution at depths greater than 5 km are driving seismicity in the Chiles-Cerro Negro region. However earthquakes are failing in a manner consistent with regional tectonics. Relative relocations reveal a structure consistent with mapped regional faults. Thus seismicity is likely controlled by an interaction of magmatic and tectonic processes. Because the regional stress field is highly compressional and the volcanoes

Burning down the brewery: Establishing and evacuating an ancient imperial colony at Cerro Baúl, Peru

PubMed Central

Moseley, Michael E.; Nash, Donna J.; Williams, Patrick Ryan; deFrance, Susan D.; Miranda, Ana; Ruales, Mario

2005-01-01

Before the Inca reigned, two empires held sway over the central Andes from anno Domini 600 to 1000: the Wari empire to the north ruled much of Peru, and Tiwanaku to the south reigned in Bolivia. Face-to-face contact came when both colonized the Moquegua Valley sierra in southern Peru. The state-sponsored Wari incursion, described here, entailed large-scale agrarian reclamation to sustain the occupation of two hills and the adjacent high mesa of Cerro Baúl. Monumental buildings were erected atop the mesa to serve an embassy-like delegation of nobles and attendant personnel that endured for centuries. Final evacuation of the Baúl enclave was accompanied by elaborate ceremonies with brewing, drinking, feasting, vessel smashing, and building burning. PMID:16293691

Comments on some of the drilling and completion problems in Cerro Prieto geothermal wells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dominguez A, B.; Sanchez G, G.

From 1960 to the present, 85 wells with a total drilling length exceeding 160,000 m have been constructed at Cerro Prieto, a modest figure compared to an oil field. This activity took place in five stages, each characterized by changes and modifications required by various drilling and well-completion problems. Initially, the technical procedures followed were similar to those used in the oil industry. However, several problems emerged as a result of the relatively high temperatures found in the geothermal reservoir. The various problems that have been encountered can be considered to be related to drilling fluids, cements and cementing operations,more » lithology, geothermal fluid characteristics, and casings and their accessories. As the importance of high temperatures and the characteristics of the geothermal reservoir fluids were better understood, the criteria were modified to optimize well-completion operations, and satisfactory results have been achieved to date.« less

A new species of Cryptonympha Lugo-Ortiz McCafferty (Ephemeroptera, Baetidae) from Cerro Duida (Venezuela).

PubMed

Derka, TomÁŠ; Nieto, Carolina

2018-02-05

The genus Cryptonympha includes three species: C. copiosa Lugo-Ortiz McCafferty, 1998; C. dasilvai Salles Francischetti, 2004 and C. genevievae Thomas, Manchon Glémet, 2013, known only from the nymphal stage. A description of the nymph of a fourth representative, Cryptonympha tracheata sp. n. is provided here, based on material collected in a blackwater stream on the slopes of the Cerro Duida mountain in south-western Venezuela. The nymph of the new species can be easily distinguished from the other species of the genus by very long tracheal gills II-VII, 2.5 times the length of each tergum, gill I small, nearly half length of gill IV and by posterior margin of terga with rounded spines. A complete description of the new species and a key for nymphs of all known Cryptonympha species are provided.

Hydrothermal alteration of sediments associated with surface emissions from the Cerro Prieto geothermal field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Valette-Silver, J.N.; Esquer P., I.; Elders, W.A.

1981-01-01

A study of the mineralogical changes associated with these hydrothermal vents was initiated with the aim of developing possible exploration tools for geothermal resources. The Cerro Prieto reservoir has already been explored by extensive deep drilling so that relationships between surface manifestations and deeper hydrothermal processes could be established directly. Approximately 120 samples of surface sediments were collected both inside and outside of the vents. The mineralogy of the altered sediments studied appears to be controlled by the type of emission. A comparison between the changes in mineralogy due to low temperature hydrothermal activity in the reservoir, seen in samplesmore » from boreholes, and mineralogical changes in the surface emission samples shows similar general trends below 180 C: increase of quartz, feldspar and illite, with subsequent disappearance of kaolinite, montmorillonite, calcite and dolomite. These mineral assemblages seem to be characteristic products of the discharge from high intensity geothermal fields.« less

Production induced boiling and cold water entry in the Cerro Prieto geothermal reservoir indicated by chemical and physical measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grant, M.A.; Truesdell, A.H.; Manon, A.

1981-01-01

Chemical and physical data suggest that the relatively shallow western part of the Cerro Prieto reservoir is bounded below by low permeability rocks, and above and at the sides by an interface with cooler water. There is no continuous permeability barrier around or immediately above the reservoir. Permeability within the reservoir is dominantly intergranular. Mixture with cooler water rather than boiling is the dominant cooling process in the natural state, and production causes displacement of hot water by cooler water, not by vapor. Local boiling occurs near most wells in response to pressure decreases, but no general vapor zone hasmore » formed.« less

Surface-water, water-quality, and ground-water assessment of the Municipio of Comerio, Puerto Rico, 1997-99

USGS Publications Warehouse

Rodríguez-Martínez, Jesús; Gómez-Gómez, Fernando; Santiago-Rivera, Luis; Oliveras-Feliciano, M. L.

2001-01-01

To meet the increasing need for a safe and adequate supply of water in the municipio of Comerio, an integrated surface-water, water-quality, and ground-water assessment of the area was conducted. The major results of this study and other important hydrologic and water-quality features were compiled in a Geographic Information System, and are presented in two 1:30,000-scale map plates to facilitate interpretation and use of the diverse water-resource data. Because the supply of safe drinking water was a critical issue during recent dry periods, the surface-water assessment portion of this study focused on analysis of low-flow characteristics in local streams and rivers. Low-flow characteristics were evaluated at one continuous-record gaging station based on graphical curve-fitting techniques and log-Pearson Type III frequency curves. Estimates of low-flow characteristics for 13 partial-record stations were generated using graphical-correlation techniques. Flow-duration characteristics for the continuous- and partial-record stations were estimated using the relation curves developed for the low-flow study. Stream low-flow statistics document the general hydrology under current land- and water-use conditions. A sanitary quality survey of streams utilized 24 sampling stations to evaluate about 84 miles of stream channels with drainage to or within the municipio of Comerio. River and stream samples for fecal coliform and fecal streptococcus analyses were collected on two occasions at base-flow conditions to evaluate the sanitary quality of streams. Bacteriological analyses indicate that about 27 miles of stream reaches within the municipio of Comerio may have fecal coliform bacteria concentrations above the water-quality goal established by the Puerto Rico Environmental Quality Board (Junta de Calidad Ambiental de Puerto Rico) for inland surface waters. Sources of fecal contamination may include illegal discharge of sewage to storm-water drains, malfunction of sanitary

Curve Number and Peakflow Responses Following the Cerro Grande Fire on a Small Watershed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Springer, E. P.; Hawkins, Richard H.

The Curve Number (CN) method is routinely used to estimate runoff and peakflows following forest fires, but there has been essentially no literature on the estimated value and temporal variation of CNs following wildland fires. In May 2000, the Cerro Grande Fire burned the headwaters of the major watersheds that cross Los Alamos National Laboratory, and a stream gauging network presented an opportunity to assess CNs following the fire. Analysis of rainfall-runoff events indicated that the pre-fire watershed response was complacent or limited watershed area contributed to runoff. The post-fire response indicated that the complacent behavior continued so the watershedmore » response was not dramatically changed. Peakflows did increase by 2 orders of magnitude following the fire, and this was hypothesized to be a function of increase in runoff volume and changes in watershed network allowing more efficient delivery of runoff. More observations and analyses following fires are needed to support definition of CNs for post-fire response and mitigation efforts.« less

2. Historic American Buildings Survey, Frederik C. Gjessing, Photographer January, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey, Frederik C. Gjessing, Photographer January, 1956 ELEVATION OF CHAPEL AND SALLY PORT TOWARDS THE COURTYARD PLAZA DE ARMAS, SAN FELIPE DEL MORRO. - Castillo de San Felipe del Morro Sally Port & Chapel, Northwest end of San Juan Island, San Juan, San Juan Municipio, PR

Far-IR measurements at Cerro Toco, Chile: FIRST, REFIR, and AERI

NASA Astrophysics Data System (ADS)

Cageao, Richard P.; Alford, J. Ashley; Johnson, David G.; Kratz, David P.; Mlynczak, Martin G.

2010-09-01

In mid-2009, the Radiative Heating in the Underexplored Bands Campaign II (RHUBC-II) was conducted from Cerro Toco, Chile, a high, dry, remote mountain plateau, 23°S , 67.8°W at 5.4km, in the Atacama Desert of Northern Chile. From this site, dominant IR water vapor absorption bands and continuum, saturated when viewed from the surface at lower altitudes, or in less dry locales, were investigated in detail, elucidating infrared (IR) absorption and emission in the atmosphere. Three Fourier Transform InfraRed (FTIR) instruments were at the site, the Far-Infrared Spectroscopy of the Troposphere (FIRST), the Radiation Explorer in the Far Infrared (REFIR), and the Atmospheric Emitted Radiance Interferometer (AERI). In a side-by-side comparison, these measured atmospheric downwelling radiation, with overlapping spectral coverage from 5 to 100μm (2000 to 100cm-1), and instrument spectral resolutions from 0.5 to 0.643cm-1, unapodized. In addition to the FTIR and other ground-based IR and microwave instrumentation, pressure/temperature/relative humidity measuring sondes, for atmospheric profiles to 18km, were launched from the site several times a day. The derived water vapor profiles, determined at times matching the FTIR measurement times, were used to model atmospheric radiative transfer. Comparison of instrument data, all at the same spectral resolution, and model calculations, are presented along with a technique for determining adjustments to line-by-line calculation continuum models. This was a major objective of the campaign.

Far-IR Measurements at Cerro Toco, Chile: FIRST, REFIR, and AERI

NASA Technical Reports Server (NTRS)

Cageao, Richard P.; Alford, J. Ashley; Johnson, David G.; Kratz, David P.; Mlynczak, Martin G.

2010-01-01

In mid-2009, the Radiative Heating in the Underexplored Bands Campaign II (RHUBC-II) was conducted from Cerro Toco, Chile, a high, dry, remote mountain plateau, 23degS , 67.8degW at 5.4km, in the Atacama Desert of Northern Chile. From this site, dominant IR water vapor absorption bands and continuum, saturated when viewed from the surface at lower altitudes, or in less dry locales, were investigated in detail, elucidating IR absorption and emission in the atmosphere. Three FTIR instruments were at the site, the Far-Infrared Spectroscopy of the Troposphere (FIRST), the Radiation Explorer in the Far Infrared (REFIR), and the Atmospheric Emitted Radiance Interferometer (AERI). In a side-by-side comparison, these measured atmospheric downwelling radiation, with overlapping spectral coverage from 5 to100um (2000 to 100/cm), and instrument spectral resolutions from 0.5 to 0.64/cm, unapodized. In addition to the FTIR and other ground-based IR and microwave instrumentation, pressure/temperature/relative humidity measuring sondes, for atmospheric profiles to 18km, were launched from the site several times a day. The derived water vapor profiles, determined at times matching the FTIR measurement times, were used to model atmospheric radiative transfer. Comparison of instrument data, all at the same spectral resolution, and model calculations, are presented along with a technique for determining adjustments to line-by-line calculation continuum models. This was a major objective of the campaign.

Spatially controlled Fe and Si isotope variations: an alternative view on the formation of the Torres del Paine pluton

NASA Astrophysics Data System (ADS)

Gajos, Norbert A.; Lundstrom, Craig C.; Taylor, Alexander H.

2016-11-01

We present new Fe and Si isotope ratio data for the Torres del Paine igneous complex in southern Chile. The multi-composition pluton consists of an approximately 1 km vertical exposure of homogenous granite overlying a contemporaneous 250-m-thick mafic gabbro suite. This first-of-its-kind spatially dependent Fe and Si isotope investigation of a convergent margin-related pluton aims to understand the nature of granite and silicic igneous rock formation. Results collected by MC-ICP-MS show a trend of increasing δ56Fe and δ30Si with increasing silica content as well as a systematic increase in δ56Fe away from the mafic base of the pluton. The marginal Torres del Paine granites have heavier Fe isotope signatures (δ56Fe = +0.25 ± 0.02 2se) compared to granites found in the interior pluton (δ56Fe = +0.17 ± 0.02 2se). Cerro Toro country rock values are isotopically light in both Fe and Si isotopic systems (δ56Fe = +0.05 ± 0.02 ‰; δ30Si = -0.38 ± 0.07 ‰). The variations in the Fe and Si isotopic data cannot be accounted for by local assimilation of the wall rocks, in situ fractional crystallization, late-stage fluid exsolution or some combination of these processes. Instead, we conclude that thermal diffusion or source magma variation is the most likely process producing Fe isotope ratio variations in the Torres del Paine pluton.

Surface-water, water-quality, and ground-water assessment of the Municipio of Carolina, Puerto Rico, 1997-99

USGS Publications Warehouse

Rodríguez-Martínez, Jesús; Gómez-Gómez, Fernando; Santiago-Rivera, Luis; Oliveras-Feliciano, M. L.

2001-01-01

To meet the increasing need for a safe and adequate supply of water in the municipio of Carolina, an integrated surface-water, water-quality, and ground-water assessment of the area was conducted. The major results of this study and other important hydrologic and water-quality features were compiled in a Geographic Information System and are presented in two 1:30,000-scale map plates to facilitate interpretation and use of the diverse water-resources data. Because the supply of safe drinking water was a critical issue during recent dry periods, the surface-water assessment portion of this study focused on analysis of low-flow characteristics in local streams and rivers. Low-flow characteristics were evaluated for one continuous-record gaging station, based on graphical curve-fitting techniques and log-Pearson Type III frequency analysis. Estimates of low-flow characteristics for seven partial-record stations were generated using graphical-correlation techniques. Flow-duration characteristics were computed for the one continuous-record gaging station and were estimated for the partial-record stations using the relation curves developed from the low-flow study. Stream low-flow statistics document the general hydrology under current land and water use. Low-flow statistics may substantially change as a result of streamflow diversions for public supply, and an increase in ground-water development, waste-water discharges, and flood-control measures; the current analysis provides baseline information to evaluate these impacts and develop water budgets. A sanitary quality survey of streams utilized 29 sampling stations to evaluate the sanitary quality of about 87 miles of stream channels. River and stream samples were collected on two occasions during base-flow conditions and were analyzed for fecal coliform and fecal streptococcus. Bacteriological analyses indicate that a significant portion of the stream reaches within the municipio of Carolina may have fecal coliform

CTIO History | CTIO

Science.gov Websites

Preserving the Dark Skies La Oficina de Protección de la Calidad del Cielo del Norte de Chile - OPCC Light Pollution StarLight Universe The World at Night (TWAN) International Dark-Sky Association (IDA) Students REU ‹› You are here CTIO Home » About » CTIO History CTIO History Brief History of THE CERRO

Soil mercury levels in the area surrounding the Cerro Prieto geothermal complex, MEXICO.

PubMed

Pastrana-Corral, M A; Wakida, F T; García-Flores, E; Rodriguez-Mendivil, D D; Quiñonez-Plaza, A; Piñon-Colin, T D J

2016-08-01

Even though geothermal energy is a renewable energy source that is seen as cost-effective and environmentally friendly, emissions from geothermal plants can impact air, soil, and water in the vicinity of geothermal power plants. The Cerro Prieto geothermal complex is located 30 km southeast of the city of Mexicali in the Mexican state of Baja California. Its installed electricity generation capacity is 720 MW, being the largest geothermal complex in Mexico. The objective of this study was to evaluate whether the emissions generated by the geothermal complex have increased the soil mercury concentration in the surrounding areas. Fifty-four surface soil samples were collected from the perimeter up to an approximate distance of 7660 m from the complex. Additionally, four soil depth profiles were performed in the vicinity of the complex. Mercury concentration in 69 % of the samples was higher than the mercury concentration found at the baseline sites. The mercury concentration ranged from 0.01 to 0.26 mg/kg. Our results show that the activities of the geothermal complex have led to an accumulation of mercury in the soil of the surrounding area. More studies are needed to determine the risk to human health and the ecosystems in the study area.

Mineralized breccia clasts: a window into hidden porphyry-type mineralization underlying the epithermal polymetallic deposit of Cerro de Pasco (Peru)

NASA Astrophysics Data System (ADS)

Rottier, Bertrand; Kouzmanov, Kalin; Casanova, Vincent; Bouvier, Anne-Sophie; Baumgartner, Lukas P.; Wälle, Markus; Fontboté, Lluís

2018-01-01

Cerro de Pasco (Peru) is known for its large epithermal polymetallic (Zn-Pb-Ag-Cu-Bi) mineralization emplaced at shallow level, a few hundred meters below the paleo-surface, at the border of a large diatreme-dome complex. Porphyry-style veins crosscutting hornfels and magmatic rock clasts are found in the diatreme breccia and in quartz-monzonite porphyry dikes. Such mineralized veins in clasts allow investigation of high-temperature porphyry-style mineralization developed in the deep portions of magmatic-hydrothermal systems. Quartz in porphyry-style veins contains silicate melt inclusions as well as fluid and solid mineral inclusions. Two types of high-temperature (> 600 °C) quartz-molybdenite-(chalcopyrite)-(pyrite) veins are found in the clasts. Early, thin (1-2 mm), and sinuous HT1 veins are crosscut by slightly thicker (up to 2 cm) and more regular HT2 veins. The HT1 vein quartz hosts CO2- and sulfur-rich high-density vapor inclusions. Two subtypes of the HT1 veins have been defined, based on the nature of mineral inclusions hosted in quartz: (i) HT1bt veins with inclusions of K-feldspar, biotite, rutile, and minor titanite and (ii) HT1px veins with inclusions of actinolite, augite, titanite, apatite, and minor rutile. Using an emplacement depth of the veins of between 2 and 3 km (500 to 800 bar), derived from the diatreme breccia architecture and the supposed erosion preceding the diatreme formation, multiple mineral thermobarometers are applied. The data indicate that HT1 veins were formed at temperatures > 700 °C. HT2 veins host assemblages of polyphase brine inclusions, generally coexisting with low-density vapor-rich inclusions, trapped at temperatures around 600 °C. Rhyolitic silicate melt inclusions found in both HT1 and HT2 veins represent melt droplets transported by the ascending hydrothermal fluids. LA-ICP-MS analyses reveal a chemical evolution coherent with the crystallization of an evolved rhyolitic melt. Quartz from both HT1 and HT2 veins

12. Detail: pier wall and undersides of encased steel beams: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Detail: pier wall and undersides of encased steel beams: easternmost steel beam span, facing west. - Puente del Cano Perdomo, Route PR-2 spanning Cano Perdomo Channel, Arecibo, Arecibo Municipio, PR

Gravimetric 3D Subsurface Modelling of the Cerro Do Jarau Structure, Rio Grande Do Sul, Brazil.

NASA Astrophysics Data System (ADS)

Giacomini, B. B.

2014-12-01

Although common in other bodies of the solar system, impact craters formed in basaltic terrains are rare on Earth and only a few examples are known. Two of these craters are located south of Brazil, the Vargeão and Vista Alegre impact craters. The Cerro do Jarau structure is not confirmed, but is a possible third Brazilian basaltic crater, formed above the Serra Geral basalt floods of the Paraná Basin like the other two. Cerro do Jarau is a 13 km circular landform that rises over 200 meters above the plains of the "pampas" in southern Brazil. The name, meaning "Jarau hills", is given after the crests of silicified and deformed Botucatu sandstones, which form a semiring of elevated hills in the northern part of the structure. This work focused on the construction of a 3D subsurface geological model that could explain a new set of ground gravimetric data. Bouguer anomalies were calculated from gravity acceleration measured at 313 stations irregularly distributed on the area of the impact structure. A regional component represented by a polynomial trend surface was extracted from the total Bouguer anomalies. The residual Bouguer map (fig. 1) shows a strong positive anomaly with a NE-SW trend, located in the northeastern part of the structure. This gravity feature is not common in other impact structures, being possibly related to a dike intrusion. However, the negative anomaly present in the center of the structure and the circular positive anomaly surrounding the central part of the structure could be related to an impact structure. The positive circular anomaly is not spatially coincident with the edges of the structure, a feature that is also observed at the Vargeão and Vista Alegre impact structures. Density values of basalts, sandstones and breccias were measured from rock samples and each average value were used as constraints for the 3D model developed with the Geosoft® VOXI Earth modelling.This model provided a better understanding of the subsurface design

Predicting floodplain boundary changes following the Cerro Grande wildfire

NASA Astrophysics Data System (ADS)

McLin, Stephen G.; Springer, Everett P.; Lane, Leonard J.

2001-10-01

A combined ArcView GIS-HEC modelling application for floodplain analysis of pre- and post-burned watersheds is described. The burned study area is located on Pajarito Plateau near Los Alamos National Laboratory (the Laboratory), where the Cerro Grande Wildfire burned 42 878 acres (17 352 ha) in May 2000. This area is dominated by rugged mountains that are dissected by numerous steep canyons having both ephemeral and perennial channel reaches. Vegetation consists of pinon-juniper woodlands located between 6000 and 7000 ft (1829-2134 m) above mean sea level (MSL), and Ponderosa pine stands between 7000 and 10000 ft MSL (2134-3048 m). Approximately 17% of the burned area is located within the Laboratory, and the remainder is located in upstream or adjacent watersheds. Pre-burn floodplains were previously mapped in 1990-91 using early HEC models as part of the hazardous waste site permitting process. Precipitation and stream gauge data provide essential information characterizing rainfall-runoff relationships before and after the fire. They also provide a means of monitoring spatial and temporal changes as forest recovery progresses. The 2000 summer monsoon began in late June and provided several significant runoff events for model calibration. HEC-HMS modelled responses were sequentially refined so that observed and predicted hydrograph peaks were matched at numerous channel locations. The 100 year, 6 h design storm was eventually used to predict peak hydrographs at critical sites. These results were compared with pre-fire simulations so that new flood-prone areas could be systematically identified. Stream channel cross-sectional geometries were extracted from a gridded 1 ft (0·3 m) digital elevation model (DEM) using ArcView GIS. Then floodpool topwidths, depths, and flow velocities were remapped using the HEC-RAS model. Finally, numerous surveyed channel sections were selectively made at crucial sites for DEM verification. These evaluations provided timely guidance

Multiple approaches to understanding the taxonomic status of an enigmatic new scorpion species of the genus Tityus (Buthidae) from the biogeographic island of Paraje Tres Cerros (Argentina)

PubMed Central

Adilardi, Renzo S.; Cajade, Rodrigo; Ramírez, Martín J.; Ceccarelli, F. Sara; Mola, Liliana M.

2017-01-01

Tityus curupi n. sp., belonging to the bolivianus complex, is described from the biogeographically distinct area of Paraje Tres Cerros in north-eastern Argentina. We also present a molecular species delimitation analysis between Tityus curupi n. sp. and its sister species Tityus uruguayensis Borelli 1901 to confirm species integrity. Furthermore, a cytogenetic analysis is presented for these two species which contain different multivalent associations in meiosis, as a consequence of chromosome rearrangements, and the highest chromosome numbers in the genus. PMID:28746406

Multiple approaches to understanding the taxonomic status of an enigmatic new scorpion species of the genus Tityus (Buthidae) from the biogeographic island of Paraje Tres Cerros (Argentina).

PubMed

Ojanguren-Affilastro, Andrés A; Adilardi, Renzo S; Cajade, Rodrigo; Ramírez, Martín J; Ceccarelli, F Sara; Mola, Liliana M

2017-01-01

Tityus curupi n. sp., belonging to the bolivianus complex, is described from the biogeographically distinct area of Paraje Tres Cerros in north-eastern Argentina. We also present a molecular species delimitation analysis between Tityus curupi n. sp. and its sister species Tityus uruguayensis Borelli 1901 to confirm species integrity. Furthermore, a cytogenetic analysis is presented for these two species which contain different multivalent associations in meiosis, as a consequence of chromosome rearrangements, and the highest chromosome numbers in the genus.

Geology, geochronology, and geochemistry of basaltic flows of the Cat Hills, Cat Mesa, Wind Mesa, Cerro Verde, and Mesita Negra, central New Mexico

USGS Publications Warehouse

Maldonado, F.; Budahn, J.R.; Peters, L.; Unruh, D.M.

2006-01-01

The geochronology, geochemistry, and isotopic compositions of basaltic flows erupted from the Cat Hills, Cat Mesa, Wind Mesa, Cerro Verde, and Mesita Negra volcanic centres in central New Mexico indicate that each of these lavas had unique origins and that the predominant mantle involved in their production was an ocean-island basalt type. The basalts from Cat Hills (0.11 Ma) and Cat Mesa (3.0 Ma) are similar in major and trace element composition, but differences in MgO contents and Pb isotopic values are attributed to a small involvement of a lower crustal component in the genesis of the Cat Mesa rocks. The Cerro Verde rock is comparable in age (0.32 Ma) to the Cat Hills lavas, but it is more radiogenic in Sr and Nd, has higher MgO contents, and has a lower La/Yb ratio. This composition is explained by the melting of an enriched mantle source, but the involvement of another crustal component cannot be disregarded. The Wind Mesa rock is characterized by similar age (4.01 Ma) and MgO contents, but it has enriched rare-earth element contents compared with the Cat Mesa samples. These are attributed to a difference in the degree of partial melting of the Cat Mesa source. The Mesita Negra rock (8.11 Ma) has distinctive geochemical and isotopic compositions that suggest a different enriched mantle and that large amounts of a crustal component were involved in generating this magma. These data imply a temporal shift in magma source regions and crustal involvement, and have been previously proposed for Rio Grande rift lavas. ?? 2006 NRC Canada.

46. View of Plaza de Armas taken through archway between ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

46. View of Plaza de Armas taken through archway between Plaza de Armas and Carmen Bastion, looking southwest - Castillo de San Felipe del Morro, Northwest end of San Juan, San Juan, San Juan Municipio, PR

91. World War II observation post, Cabarello level looking from ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

91. World War II observation post, Cabarello level looking from Carmen Bastion (similar to HABS PR-48-24) - Castillo de San Felipe del Morro, Northwest end of San Juan, San Juan, San Juan Municipio, PR

Regional and local networks of horizontal control, Cerro Prieto geothermal area

USGS Publications Warehouse

Massey, B.L.

1979-01-01

The Cerro Prieto geothermal area in the Mexicali Valley 30 km southeast of Mexicali, Baja California, is probably deforming due to (1) the extraction of large volumes of steam and hot water, and (2) active tectonism. Two networks of precise horizontal control were established in Mexicali Valley by the U.S. Geological Survey in 1977 - 1978 to measure both types of movement as they occur. These networks consisted of (1) a regional trilateration net brought into the mountain ranges west of the geothermal area from survey stations on an existing U.S. Geological Survey crustal-strain network north of the international border, and (2) a local net tied to stations in the regional net and encompassing the area of present and planned geothermal production. Survey lines in this net were selected to span areas of probable ground-surface movements in and around the geothermal area. Electronic distance measuring (EDM) instruments, operating with a modulated laser beam, were used to measure the distances between stations in both networks. The regional net was run using a highly precise long-range EDM instrument, helicopters for transportation of men and equipment to inaccessible stations on mountain peaks, and a fixed wing airplane flying along the line of sight. Precision of measurements with this complex long-range system approached 0-2 ppm of line length. The local net was measured with a medium-range EDM instrument requiring minimal ancillary equipment. Precision of measurements with this less complex system approached 3 ppm for the shorter line lengths. The detection and analysis of ground-surface movements resulting from tectonic strains or induced by geothermal fluid withdrawal is dependent on subsequent resurveys of these networks. ?? 1979.

Surface-Water, Water-Quality, and Ground-Water Assessment of the Municipio of Mayaguez, Puerto Rico, 1999-2002

USGS Publications Warehouse

Rodríguez-Martínez, Jesús; Santiago-Rivera, Luis; Guzman-Rios, Senen; Gómez-Gómez, Fernando; Oliveras-Feliciano, Mario L.

2004-01-01

The surface-water assessment portion of this study focused on analysis of low-flow characteristics in local streams and rivers, because the supply of safe drinking water was a critical issue during recent dry periods. Low-flow characteristics were evaluated at one continuous-record gaging station based on graphical curve-fitting techniques and log-Pearson Type III frequency curves. Estimates of low-flow characteristics for 20 partial-record stations were generated using graphical-correlation techniques. Flow-duration characteristics for the continuous- and partial-record stations were estimated using the relation curves developed for the low-flow study. Stream low-flow statistics document the general hydrology under current land use, water-use, and climatic conditions. A survey of streams and rivers utilized 37 sampling stations to evaluate the sanitary quality of about 165 miles of stream channels. River and stream samples for fecal coliform and fecal streptococcus analyses were collected on two occasions at base-flow conditions. Bacteriological analyses indicate that a significant portion of the stream reaches within the municipio of Mayaguez may have fecal coliform bacteria concentrations above the water-quality goal (standard) established by the Puerto Rico Environmental Quality Board (Junta de Calidad Ambiental de Puerto Rico) for inland surface waters. Sources of fecal contamination may include: illegal discharge of sewage to storm-water drains, malfunctioning sanitary sewer ejectors, clogged and leaking sewage pipes, septic tank leakage, unfenced livestock, and runoff from livestock pens. Long-term fecal coliform data from five sampling stations located within or in the vicinity of the municipio of Mayaguez have been in compliance with the water-quality goal for fecal coliform concentration established in July 1990. Geologic, topographic, soil, hydrogeologic, and streamflow data were compiled into a database and used to divide the municipio of Mayaguez into

EJERCICIO Y LA DETECCION DEL MAL AGUDO DE MONTAÑA GRAVE

PubMed Central

Garófoli, Adrián; Montoya, Paola; Elías, Carlos; Benzo, Roberto

2012-01-01

El Mal Agudo de Montaña (MAM) es un conjunto de síntomas inespecíficos padecidos por sujetos que ascienden rápidamente desde baja a alta altura sin adecuada aclimatación. Usualmente es autolimitado, pero las formas graves (edema pulmonar y cerebral) pueden causar la muerte. La hipoxemia exagerada en reposo está relacionada con el desarrollo de MAM pero su valor predictivo es limitado. Dado que el ejercicio en altura se acompaña de mayor hipoxemia y síntomas, postulamos el valor predictivo de un simple test de ejercicio para pronosticar MAM grave. Se estudió el valor predictivo de la saturación de oxígeno en reposo y ejercicio submáximo a 2 700m y 4 300m en 63 sujetos que ascendían al cerro Aconcagua (6 962m). Se consideró desaturación de oxígeno con ejercicio a una disminución >=5% respecto al reposo. Se utilizó la escala de Lake-Louise para establecer la presencia de MAM grave. 6 sujetos presentaron MAM grave (9.5%) y requirieron evacuación. La saturación de oxígeno en reposo a 2 700m no fue significativa para clasificar sujetos que luego desarrollaron MAM grave. Por el contrario, la asociación de desaturación durante el ejercicio a 2 700m más la saturación inapropiada en reposo a 4 300m fue significativa para clasificar a los sujetos que desarrollaron MAM grave con un valor predictivo positivo de 80% y un valor predictivo negativo del 97%. Nuestros resultados son relevantes para el montañismo y sugieren la adición de un simple test de ejercicio en la predicción del MAM grave. PMID:20228017

Downwelling Far-Infrared Radiance Spectra Measured by FIRST at Cerro Toco, Chile

NASA Astrophysics Data System (ADS)

Mast, J. C.; Mlynczak, M. G.; Cageao, R.; Kratz, D. P.; Latvakoski, H.; Johnson, D. G.; Mlawer, E. J.; Turner, D. D.

2015-12-01

The Far-Infrared Spectroscopy of the Troposphere (FIRST) instrument is a Fourier transform spectrometer developed by NASA Langley Research Center in collaboration with the Space Dynamics Laboratory and the Harvard-Smithsonian Center for Astrophysics. FIRST was initially developed for measuring the far-infrared portion of Earth's longwave spectrum as a balloon borne instrument and later was reconfigured to operate as a ground-based instrument. In its current ground-based configuration FIRST was deployed at 17500 ft on Cerro Toco, a mountain in the Atacama Desert of Chile, from August to October, 2009. There the integrated precipitable water (IPW) was as low as 0.02 cm. FIRST measurements from days with IPW between 0.024 and 0.035 cm during the campaign are presented here between 200 cm-1 and 800 cm-1. Significant spectral development in the far-IR is observed over the entire 200 cm-1 to 800 cm-1 band. Water vapor and temperature profiles from radiosonde and GVRP measurements are used as inputs to the AER Line-by-Line Radiative Transfer Model (LBLRTM) utilizing the AER v3.2 line parameter database. Uncertainties in both the measured and modeled radiances are accounted for in this study. The residual LBLRTM - FIRST is calculated to assess agreement between the measured and modeled spectra. Measured and model radiances generally agree to within the combined uncertainties for wavenumbers greater than 360 cm-1. At wavenumbers less than 360 cm-1 persistent troughs in the residual are present outside of the combined uncertainties. These features are present on different days and at different water vapor amounts. Possible solutions for these features are discussed.

The CCAT-prime Extreme Field-of-View Submillimeter Telescope on Cerro Chajnantor

NASA Astrophysics Data System (ADS)

Koopman, Brian; Bertoldi, Frank; Chapman, Scott; Fich, Michel; Giovanelli, Riccardo; Haynes, Martha P.; Herter, Terry L.; Murray, Norman W.; Niemack, Michael D.; Riechers, Dominik; Schilke, Peter; Stacey, Gordon J.; Stutzki, Juergen; CCAT-prime Collaboration

2017-01-01

CCAT-prime is a six meter aperture off-axis submillimeter telescope that we plan to build at 5600m elevation on Cerro Chajnantor in Chile. The CCAT-prime optics are based on a cross-Dragone design with high throughput and a wide field-of-view optimized to increase the mapping speed of next generation cosmic microwave background (CMB) observations. These characteristics make CCAT-prime an excellent platform for a wide range of next generation millimeter and submillimeter science goals, and a potential platform for CMB stage-IV measurements. Here we present the telescope design for CCAT-prime and review the science goals.Taking advantage of the high elevation site, the first generation instrument for CCAT-prime will measure seven different frequency bands from 350um to 3mm. These seven bands will enable precise measurements of the Sunyaev-Zel’dovich effects (SZE) by separating contributions from CMB, thermal SZE, kinetic SZE, bright submm galaxies, and radio sources with a goal of extracting the peculiar velocities from a large number of galaxy clusters. Additional science priorities for CCAT-prime include: Galactic Ecology studies of the dynamic intersteller medium by mapping the fine structure lines [CI], [CII] and [NII] as well as high-excitation CO lines at the shortest wavelength bands; high redshift intensity mapping of [CII] emission from star-forming galaxies that likely dominates cosmic reionization at z~5-9 to probe the Epoch of Reionization; and next generation CMB polarization measurements to constrain inflation and cosmological models. The CCAT-prime facility will further our understanding of astrophysical processes from moments after the Big Bang to the present-day evolution of the Milky Way.

37. Closeup of stairs in previous photo, leading up to ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

37. Close-up of stairs in previous photo, leading up to El Macho and down to Plaza de Armas, from Santa Barbara Bastion, viewed from northwest - Castillo de San Felipe del Morro, Northwest end of San Juan, San Juan, San Juan Municipio, PR

23. General view of the top gundeck looking northwest from ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. General view of the top gundeck looking northwest from Austria Bastion showing ramp down and parapet wall of the Plaza de Armas on lower level - Castillo de San Felipe del Morro, Northwest end of San Juan, San Juan, San Juan Municipio, PR

Chemical variations in the Cerro de Mercado (Durango, Mexico) fluorapatite: Assessing the effect of heterogeneity on a geochronologic standard.

NASA Astrophysics Data System (ADS)

Boyce, J. W.; Hodges, K. V.

2001-12-01

Despite the lack of an official pronouncement, the fluorapatite of Cerro de Mercado, Durango, Mexico has become the de facto standard for (U-Th)/He geochronology. In addition to being relatively inclusion-free and easily obtained, these crystals are commonly in excess of 5mm in diameter, permitting the removal of the outer skin of the crystal, theoretically eliminating the alpha-ejection correction. However, bulk analyses of the Durango fluorapatite indicate a substantial variation in U and Th concentrations from aliquot to aliquot (167-238 ppm Th; 9.7-12.3 ppm U, [1]). If similar variations were to occur on the sub-grain scale, small fragments of single crystals could contain helium excesses or deficiencies due to alpha-ejection exchange between zones with varying parent element content. We have performed a series of experiments to quantify the intra-grain variation in U and Th, in order to model the effect of this variation on ages determined on Durango fluorapatite. X-ray maps show concentric zonation in U and Th, with similar, but more apparently pronounced zonation in Si and Cl. Preliminary laser-ablation ICPMS data indicate, not surprisingly, that intra-grain variations in U and Th concentrations obtained by analysis of ~35 μ m spots are larger than that which had been previously obtained by bulk analytical techniques (with overall concentrations greater than for bulk analyses). Thus far, analyses yield U concentrations varying from 11 to 16 ppm, and Th concentrations ranging from 220 to 340 ppm. Modeling underway suggests that parent element variations on the order of 50%, such as those observed, and the resulting differential alpha-exchange could lead to several percent error in age, for ~100 μ m fragments. The effect scales inversely with fragment size, with 300 μ m fragments (roughly the size of a large, single grain analysis) having only ~1% error. This may offer an explanation for the previously observed inability to reproduce ages for the Durango

Origin and evolution of mineralizing fluids and exploration of the Cerro Quema Au-Cu deposit (Azuero Peninsula, Panama) from a fluid inclusion and stable isotope perspective

USGS Publications Warehouse

Corral, Isaac; Cardellach, Esteve; Corbella, Merce; Canals, Angels; Griera, Albert; Gomez-Gras, David; Johnson, Craig A.

2017-01-01

Cerro Quema is a high sulfidation epithermal Au-Cu deposit with a measured, indicated and inferred resource of 35.98 Mt. @ 0.77 g/t Au containing 893,600 oz. Au (including 183,930 oz. Au equiv. of Cu ore). It is characterized by a large hydrothermal alteration zone which is interpreted to represent the lithocap of a porphyry system. The innermost zone of the lithocap is constituted by vuggy quartz with advanced argillic alteration locally developed on its margin, enclosed by a well-developed zone of argillic alteration, grading to an external halo of propylitic alteration. The mineralization occurs in the form of disseminations and microveinlets of pyrite, chalcopyrite, enargite, tennantite, and trace sphalerite, crosscut by quartz, barite, pyrite, chalcopyrite, sphalerite and galena veins.Microthermometric analyses of two phase (L + V) secondary fluid inclusions in igneous quartz phenocrysts in vuggy quartz and advanced argillically altered samples indicate low temperature (140–216 °C) and low salinity (0.5–4.8 wt% NaCl eq.) fluids, with hotter and more saline fluids identified in the east half of the deposit (Cerro Quema area).Stable isotope analyses (S, O, H) were performed on mineralization and alteration minerals, including pyrite, chalcopyrite, enargite, alunite, barite, kaolinite, dickite and vuggy quartz. The range of δ34S of sulfides is from − 4.8 to − 12.7‰, whereas δ34S of sulfates range from 14.1 to 17.4‰. The estimated δ34SΣS of the hydrothermal fluid is − 0.5‰. Within the advanced argillic altered zone the δ34S values of sulfides and sulfates are interpreted to reflect isotopic equilibrium at temperatures of ~ 240 °C. The δ18O values of vuggy quartz range from 9.0 to 17.5‰, and the δ18O values estimated for the vuggy quartz-forming fluid range from − 2.3 to 3.0‰, indicating that it precipitated from mixing of magmatic fluids with surficial fluids. The δ18O of kaolinite ranges from 12.7 to 18.1‰ and �

Adaptación al español y validación de criterio de una escala para la tamización de problemas emocionales y del comportamiento en la primera infancia.

PubMed

Cano, Luz Helena; Acosta, María Natalia; Pulido, Adriana

2018-05-01

Introducción. La detección temprana del riesgo de problemas emocionales y del comportamiento en niños puede contribuir al desarrollo de estrategias que promuevan la salud mental desde la primera infancia. En Colombia no existe una herramienta validada para dicha detección.Objetivos. Seleccionar, adaptar y establecer la validez de criterio de una escala de tamización de problemas emocionales y del comportamiento en niños menores de seis años.Materiales y métodos. A partir de una revisión de la literatura y un consenso de expertos, se seleccionó la herramienta Early Childhood Screening Assessment (ECSA). Posteriormente, se llevó a cabo su adaptación lingüística y se determinó la validez de criterio mediante una curva de características de recibidor-operador (Receiver Operating Characteristic, ROC), y se la comparó con el cuestionario Child Behavior Checklist (CBCL 1,5-5). En el estudio participaron 206 cuidadores de niños entre el año y medio y los seis años de edad de la ciudad de Tunja y el municipio de Sopó.Resultados. La puntuación del ECSA presentó una buena correlación con la puntuación t total del CBCL 1,5-5 (ro de Spearman=0,75; p<0,01). La escala ECSA tuvo una sensibilidad de 86 % y una especificidad de 82 % al establecer un punto de corte de 24 para la población estudiada.Conclusión. En este primer estudio de adaptación y validación de la versión en español de la escala ECSA, se detectaron buenos valores de sensibilidad y especificidad para la tamización de problemas emocionales y del comportamiento en la primera infancia.

Characterization of post-fire surface cover, soils, and burn severity at the Cerro Grande Fire, New Mexico, using hyperspectral and multispectral remote sensing

USGS Publications Warehouse

Kokaly, R.F.; Rockwell, B.W.; Haire, S.L.; King, T.V.V.

2007-01-01

Forest fires leave behind a changed ecosystem with a patchwork of surface cover that includes ash, charred organic matter, soils and soil minerals, and dead, damaged, and living vegetation. The distributions of these materials affect post-fire processes of erosion, nutrient cycling, and vegetation regrowth. We analyzed high spatial resolution (2.4??m pixel size) Airborne Visible and Infrared Imaging Spectrometer (AVIRIS) data collected over the Cerro Grande fire, to map post-fire surface cover into 10 classes, including ash, soil minerals, scorched conifer trees, and green vegetation. The Cerro Grande fire occurred near Los Alamos, New Mexico, in May 2000. The AVIRIS data were collected September 3, 2000. The surface cover map revealed complex patterns of ash, iron oxide minerals, and clay minerals in areas of complete combustion. Scorched conifer trees, which retained dry needles heated by the fire but not fully combusted by the flames, were found to cover much of the post-fire landscape. These scorched trees were found in narrow zones at the edges of completely burned areas. A surface cover map was also made using Landsat Enhanced Thematic Mapper plus (ETM+) data, collected September 5, 2000, and a maximum likelihood, supervised classification. When compared to AVIRIS, the Landsat classification grossly overestimated cover by dry conifer and ash classes and severely underestimated soil and green vegetation cover. In a comparison of AVIRIS surface cover to the Burned Area Emergency Rehabilitation (BAER) map of burn severity, the BAER high burn severity areas did not capture the variable patterns of post-fire surface cover by ash, soil, and scorched conifer trees seen in the AVIRIS map. The BAER map, derived from air photos, also did not capture the distribution of scorched trees that were observed in the AVIRIS map. Similarly, the moderate severity class of Landsat-derived burn severity maps generated from the differenced Normalized Burn Ratio (dNBR) calculation

Thermal Models of the Ocean Floor: from Wegener to Cerro Prieto

NASA Astrophysics Data System (ADS)

Sclater, J. G.; Negrete-Aranda, R.

2017-12-01

Wegener (1925) argued that hot rock could explain the shallower depths of ridges in the center of the Atlantic Ocean. Hess (1963) proposed that the intrusion of molten rock occurred at a world encircling mid-ocean ridge system. However, he accounted for the elevation of the ridges by the formation of serpentinite and thermal convection. Langseth et al. (1966) provided the major advance by using a 100 km thick plate to argue such a concept could not explain the depth, heat flow versus distance relations. They had the correct model but misinterpreted the data. Reformulating theoretically, McKenzie (1967) created the generally accepted thermal model for the ocean floor. Unfortunately, in attempting to match erroneously low heat flow data, he used a 50 km thick plate. Addition of the effect of water and the realization of the importance of advective flow, enabled various groups to create thermal plate models that accounted for the heat flow and depth age relations. From this came the understanding of hydrothermal circulation in the oceanic crust, the thermal boundary layer concept of the oceanic plate and the realization that all thermal models differed only in the way the different groups had chosen to analyze the data. During the past 40 years many have applied similar concepts to continental margins: (1) Measurement of subsidence of the Atlantic margin, continental stretching and a Time Temperature, Depth and Maturation analysis of continental basins have created the field of Basin Analysis; (2) Changes in heat flow at ocean continent boundaries have determined the position of the transition and (3) In attempting to examine the ocean continent transition process in the northernmost basin of the Gulf of California, Neumann et al (in press) observed conductive heat flow values greater than 0.75 Watts, at a depth of < 150 m, along a 10 km section of a profile across the southern extension of the Cerro Prieto fault. The magnitude of these values overwhelms local

A GIS-based hillslope erosion and sediment delivery model and its application in the Cerro Grande burn area

NASA Astrophysics Data System (ADS)

Wilson, Cathy J.; Carey, J. William; Beeson, Peter C.; Gard, Marvin O.; Lane, Leonard J.

2001-10-01

An Erratum has been published for this article in Hydrological Processes 16(5) 2002, 1130-1130.A profile-based, analytical hillslope erosion model (HEM) is integrated into a geographical information system (GIS) framework to provide a tool to assess the impact of the Cerro Grande fire on erosion and sediment delivery to the many streams draining the burn area. The model, HEM-GIS, calculates rill and interrill erosion, transport and deposition along digital flow-pathways generated with GIS software. This new erosion and sediment yield technology accounts for complex terrain attributes and their impact on the connectivity of sediment transport pathways from source areas to streams. GIS digital spatial data, including elevation, vegetation cover, burn severity and soil type, are used as input to the model. Output includes spatially distributed predictions of total event-based sediment yield (tonnes or kilograms per square metre). Here the model is applied across an 800 km2 region of the Pajarito Plateau watershed to assess the sedimentation risks associated with a 100 year design rain event. Although unvalidated for the design storm, the model predicts that the fire may cause runoff to increase by three to six times, and sediment yield to increase by more than an order of magnitude. Published in 2001 John Wiley & Sons, Ltd.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dolan, Sean Gregory; Berryman, Judy; Shackley, M. Steven

Eden projectile points associated with the Cody complex are underrepresented in the late Paleoindian record of the American Southwest. EDXRF analysis of an obsidian Eden point from a site in Sierra County, New Mexico demonstrates this artifact is from the Cerro del Medio (Valles Rhyolite) source in the Jemez Mountains. Lastly, we contextualize our results by examining variability in obsidian procurement practices beyond the Cody heartland in southcentral New Mexico.

The source provenance of an obsidian Eden point from Sierra County, New Mexico

DOE PAGES

Dolan, Sean Gregory; Berryman, Judy; Shackley, M. Steven

2016-01-02

Eden projectile points associated with the Cody complex are underrepresented in the late Paleoindian record of the American Southwest. EDXRF analysis of an obsidian Eden point from a site in Sierra County, New Mexico demonstrates this artifact is from the Cerro del Medio (Valles Rhyolite) source in the Jemez Mountains. Lastly, we contextualize our results by examining variability in obsidian procurement practices beyond the Cody heartland in southcentral New Mexico.

Columnar jointing in vapor-phase-altered, non-welded Cerro Galán Ignimbrite, Paycuqui, Argentina

USGS Publications Warehouse

Wright, Heather M.; Lesti, Chiara; Cas, Ray A.F.; Porreca, Massimiliano; Viramonte, Jose G.; Folkes, Christopher B.; Giordano, Guido

2011-01-01

Columnar jointing is thought to occur primarily in lavas and welded pyroclastic flow deposits. However, the non-welded Cerro Galán Ignimbrite at Paycuqui, Argentina, contains well-developed columnar joints that are instead due to high-temperature vapor-phase alteration of the deposit, where devitrification and vapor-phase crystallization have increased the density and cohesion of the upper half of the section. Thermal remanent magnetization analyses of entrained lithic clasts indicate high emplacement temperatures, above 630°C, but the lack of welding textures indicates temperatures below the glass transition temperature. In order to remain below the glass transition at 630°C, the minimum cooling rate prior to deposition was 3.0 × 10−3–8.5 × 10−2°C/min (depending on the experimental data used for comparison). Alternatively, if the deposit was emplaced above the glass transition temperature, conductive cooling alone was insufficient to prevent welding. Crack patterns (average, 4.5 sides to each polygon) and column diameters (average, 75 cm) are consistent with relatively rapid cooling, where advective heat loss due to vapor fluxing increases cooling over simple conductive heat transfer. The presence of regularly spaced, complex radiating joint patterns is consistent with fumarolic gas rise, where volatiles originated in the valley-confined drainage system below. Joint spacing is a proxy for cooling rates and is controlled by depositional thickness/valley width. We suggest that the formation of joints in high-temperature, non-welded deposits is aided by the presence of underlying external water, where vapor transfer causes crystallization in pore spaces, densifies the deposit, and helps prevent welding.

Storm Water Quality in Los Alamos Canyon following the Cerro Grande Fire

DOE Office of Scientific and Technical Information (OSTI.GOV)

M. Johansen; B. Enz; B. Gallaher

In May 2000, the Cerro Grande Fire burned about 7400 acres of forest on the Los Alamos National Laboratory (LANL) and about 10,000 acres in watersheds above LANL on Santa Fe National Forest lands. The resulting burned landscapes raised concerns of increased storm water runoff and transport of contaminants by runoff in the canyons traversing LANL. On June 2 and 3, 2000, rain fell in the Los Alamos Canyon watershed generating storm water runoff in the canyon bottom. This event was important in that it was the first significant runoff on LANL following the fire and occurred in a canyonmore » containing known legacy waste sites. Samples from this runoff were analyzed for radionuclide, metal, inorganic, and organic constituents. Results show radionuclide concentrations at or below previous (pre-fire) maximum levels at locations on LANL and downstream. However, greater concentrations of some fallout-associated radionuclides (cesium-137 and strontium-90) were seen arriving on LANL from upstream areas compared to pre-fire conditions. Tests indicate most of the radionuclides in the samples were bound to sediments, not dissolved in water. Most radionuclide concentrations in sediments were below LANL Screening Action Levels, with cesium-137 and strontium-90 as exceptions. Most radionuclide concentrations in samples taken at LANL's downstream boundary were greater than those taken upstream, indicating the presence of contributing sources on LANL. For comparison purposes, doses were calculated on a mrem per liter of unfiltered water basis for 11 radionuclides commonly associated with atmospheric fallout and with LANL operations. The maximum dose was 0.094 mrem per liter unfiltered water and was largely associated with plutonium-239/240. In contrast, all filtered samples had total doses less than 0.001 mrem per liter. Compared to past data, potential doses were not increased by the fire during this initial runoff event. Of the 25 metals tested for, seven were above pre

Planning and Analysis of Fractured Rock Injection Tests in the Cerro Brillador Underground Laboratory, Northern Chile

NASA Astrophysics Data System (ADS)

Fairley, J. P., Jr.; Oyarzún L, R.; Villegas, G.

2015-12-01

Early theories of fluid migration in unsaturated fractured rock hypothesized that matrix suction would dominate flow up to the point of matrix saturation. However, experiments in underground laboratories such as the ESF (Yucca Mountain, NV) have demonstrated that liquid water can migrate significant distances through fractures in an unsaturated porous medium, suggesting limited interaction between fractures and unsaturated matrix blocks and potentially rapid transmission of recharge to the sat- urated zone. Determining the conditions under which this rapid recharge may take place is an important factor in understanding deep percolation processes in arid areas with thick unsaturated zones. As part of an on-going, Fondecyt-funded project (award 11150587) to study mountain block hydrological processes in arid regions, we are plan- ning a series of in-situ fracture flow injection tests in the Cerro Brillador/Mina Escuela, an underground laboratory and teaching facility belonging to the Universidad la Serena, Chile. Planning for the tests is based on an analytical model and curve-matching method, originally developed to evaluate data from injection tests at Yucca Mountain (Fairley, J.P., 2010, WRR 46:W08542), that uses a known rate of liquid injection to a fracture (for example, from a packed-off section of borehole) and the observed rate of seepage discharging from the fracture to estimate effective fracture aperture, matrix sorptivity, fracture/matrix flow partitioning, and the wetted fracture/matrix interac- tion area between the injection and recovery points. We briefly review the analytical approach and its application to test planning and analysis, and describe the proposed tests and their goals.

40 CFR 81.355 - Puerto Rico.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Municipio San German Municipio San Juan Municipio San Lorenzo Municipio San Sebastian Municipio Santa Isabel... Municipio Rincon Municipio Rio Grande Municipio Sabana Grande Municipio Salinas Municipio San German... Rincón Municipio Río Grande Municipio Sabana Grande Municipio Salinas Municipio San Germán Municipio San...

Implications for organic maturation studies of evidence of a geologically rapid increase and stabilization of vitrinite reflectance at peak temperature: Cerro Prieto geothermal system, Mexico

USGS Publications Warehouse

Barker, C.E.

1991-01-01

A short-term rapid heating and cooling of the rock in well M-94 below 1300 m was caused by a pulse of hot water passing through the edge of the Cerro Prieto, Mexico, geothermal system. Below 1300 m, the peak paleotemperatures were about 225-250??C, but equilibrium well log temperatures indicate a decrease to 150-210??C at present. This hot water pulse sharply increased vitrinite reflectance to levels comparable to those measured in the central part of the system, even though studies of apatite fission-track annealing indicate that the duration of heating was only 100-101 yr in M-94, in contrast to 103-104 yr in the central part of the system. The quick change of the vitrinite reflectance geothermometer indicates that thermal maturation reactions can stabilize, after a geologically short period of heating, to a level consistent with peak temperature under moderate to high-temperature diagenesis in open, fluid-rich, geothermal systems. -from Author

DEL phenotype.

PubMed

Kwon, Dong H; Sandler, S G; Flegel, Willy A

2017-09-01

DEL red blood cells (RBCs) type as D- by routine serologic methods and are transfused routinely, without being identified as expressing a very weak D antigen, to D- recipients. DEL RBCs are detected only by adsorption and elution of anti-D or by molecular methods. Most DEL phenotypes have been reported in population studies conducted in East Asia, although DEL phenotypes have been detected also among Caucasian individuals. Approximately 98 percent of DEL phenotypes in East Asians are associated with the RHD*DEL1 or RHD*01EL.01 allele. The prevalence of DEL phenotypes has been reported among D- Han Chinese (30%), Japanese (28%), and Korean (17%) populations. The prevalence of DEL phenotypes is significantly lower among D- Caucasian populations (0.1%). Among the 3-5 percent of African individuals who are D-, there are no reports of the DEL phenotype. Case reports from East Asia indicate that transfusion of DEL RBCs to D- recipients has been associated with D alloimmunization. East Asian immigrants constitute 2.1 percent of the 318.9 million persons residing in the United States, and an estimated 2.8 percent are blood donors. Using these statistics, we estimate that 68-683 units of DEL RBCs from donors of East Asian ancestry are transfused as D- annually in the United States. Given the reports from East Asia of D alloimmunization attributed to transfusion of DEL RBCs, one would expect an occasional report of D alloimmunization in the United States following transfusion of DEL RBCs to a D- recipient. If such cases do occur, the most likely reason that they are not detected is the absence of active post-transfusion monitoring for formation of anti-D.

44 CFR 295.50 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Glossary § 295.50 Definitions... it sat, resulting from the Cerro Grande Fire. Discount to Net Present Value means a reduction of an...-Federal entity that suffered Loss resulting from the Cerro Grande Fire and any entity that provided...

44 CFR 295.50 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Glossary § 295.50 Definitions... it sat, resulting from the Cerro Grande Fire. Discount to Net Present Value means a reduction of an...-Federal entity that suffered Loss resulting from the Cerro Grande Fire and any entity that provided...

44 CFR 295.50 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Glossary § 295.50 Definitions... it sat, resulting from the Cerro Grande Fire. Discount to Net Present Value means a reduction of an...-Federal entity that suffered Loss resulting from the Cerro Grande Fire and any entity that provided...

44 CFR 295.50 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Glossary § 295.50 Definitions... it sat, resulting from the Cerro Grande Fire. Discount to Net Present Value means a reduction of an...-Federal entity that suffered Loss resulting from the Cerro Grande Fire and any entity that provided...

12. Photocopy of drawing (this photograph is an 8''x 10''contact ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Photocopy of drawing (this photograph is an 8''x 10''contact print; September, 1986 as built drawing by D. Monclova, in possession of the Highway Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Santiago (sic) Channel, Route no. 2 km. 75.50, Arecibo, P.R. Bridge no. 53. No. 2 of 2. - Puente del Cano Carate, Spanning Cano Carate Channel, Arecibo, Arecibo Municipio, PR

Mexicali aquifer and its relation with the Colorado river and the Cerro Prieto geothermal reservoir

NASA Astrophysics Data System (ADS)

Ramirez-Hernandez, J.; Reyes-Lopez, J. A.; Carreon-Diazconti, C.; Lazaro-Mancilla, O.

2008-05-01

Until some years ago the Colorado River has been the main recharge source of the Mexicali and the Imperial Valley aquifers. River discharge interruption after the constructions of dams upstream (i.e. Parker, Davis and Hoover) and the creation of great irrigation systems in both Valleys have modified their dynamics. Currently, the distribution of water recharge is the network of irrigation and drainage channels that distribute water to more than 500.000 ha. The chemical quality of the recharge water also has changed because the irrigation run-off water has become more mineralized. On the other hand, the intense steam exploitation of the Cerro Prieto geothermal reservoir has inverted the flow direction from the Volcano Lagoon area that until the 60s constituted the discharge zone of the aquifer and the geothermal reservoir. In this work, changes in the aquifer water recharge regime, the phreatic level and the water chemical quality are analyzed. It was found that after the reduction of the annual water extraction from aquifer up to 750X106 m3, the static levels have reached a dynamic balance that could be altered if water seepage from the irrigation channels, specially from the All American Channel, is reduced. The total dissolved solids (TDS) concentration has increased from 1000 ppm in 1970 to 1800 ppm in 2005. The water of recent infiltration, the gradual cooling of the shallowest strata of the geothermal reservoir, and the almost total disappearance of the hydrothermal surface manifestations are evidences of groundwater flow inversion. The new source of groundwater recharge due to seepage of evaporation disposal geothermal brine pond is documented. This pond incorporates water with a very different chemical composition to the groundwater system. Therefore, mineralization of the shallow aquifer layers and the soil contamination process are identified. It was concluded that the aquifer hydrodynamics in the Valley of Mexicali depends on the irrigation system more

Ecological Impacts of the Cerro Grande Fire: Predicting Elk Movement and Distribution Patterns in Response to Vegetative Recovery through Simulation Modeling October 2005

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rupp, Susan P.

2005-10-01

In May 2000, the Cerro Grande Fire burned approximately 17,200 ha in north-central New Mexico as the result of an escaped prescribed burn initiated by Bandelier National Monument. The interaction of large-scale fires, vegetation, and elk is an important management issue, but few studies have addressed the ecological implications of vegetative succession and landscape heterogeneity on ungulate populations following large-scale disturbance events. Primary objectives of this research were to identify elk movement pathways on local and landscape scales, to determine environmental factors that influence elk movement, and to evaluate movement and distribution patterns in relation to spatial and temporal aspectsmore » of the Cerro Grande Fire. Data collection and assimilation reflect the collaborative efforts of National Park Service, U.S. Forest Service, and Department of Energy (Los Alamos National Laboratory) personnel. Geographic positioning system (GPS) collars were used to track 54 elk over a period of 3+ years and locational data were incorporated into a multi-layered geographic information system (GIS) for analysis. Preliminary tests of GPS collar accuracy indicated a strong effect of 2D fixes on position acquisition rates (PARs) depending on time of day and season of year. Slope, aspect, elevation, and land cover type affected dilution of precision (DOP) values for both 2D and 3D fixes, although significant relationships varied from positive to negative making it difficult to delineate the mechanism behind significant responses. Two-dimensional fixes accounted for 34% of all successfully acquired locations and may affect results in which those data were used. Overall position acquisition rate was 93.3% and mean DOP values were consistently in the range of 4.0 to 6.0 leading to the conclusion collar accuracy was acceptable for modeling purposes. SAVANNA, a spatially explicit, process-oriented ecosystem model, was used to simulate successional dynamics. Inputs to

Heterogeneous pumice populations in the 2.08-Ma Cerro Galán Ignimbrite: implications for magma recharge and ascent preceding a large-volume silicic eruption

NASA Astrophysics Data System (ADS)

Wright, Heather M. N.; Folkes, Chris B.; Cas, Raymond A. F.; Cashman, Katharine V.

2011-12-01

Triggering mechanisms of large silicic eruptions remain a critical unsolved problem. We address this question for the ~2.08-Ma caldera-forming eruption of Cerro Galán volcano, Argentina, which produced distinct pumice populations of two colors: grey (5%) and white (95%) that we believe may hold clues to the onset of eruptive activity. We demonstrate that the color variations correspond to both textural and compositional variations between the clast types. Both pumice types have bulk compositions of high-K, high-silica dacite to low-silica rhyolite, but there are sufficient compositional differences (e.g., ~150 ppm lower Ba at equivalent SiO2 content and 0.03 wt.% higher TiO2 in white pumice than grey) to suggest that the two pumice populations are not related by simple fractionation. Trace element concentrations in crystals mimic bulk variations between clast types, with grey pumice containing elevated Ba, Cu, Pb, and Zn concentrations in both bulk samples (average Cu, Pb, and Zn concentrations are 27, 35, and 82 in grey pumice vs. 11, 19, and 60 in white pumice) and biotite phenocrysts and white pumice showing elevated Li concentrations in biotite and plagioclase phenocrysts. White and grey clasts are also texturally distinct: White pumice clasts contain abundant phenocrysts (44-57%), lack microlites, and have highly evolved groundmass glass compositions (76.4-79.6 wt.% SiO2), whereas grey pumice clasts contain a lower percentage of phenocrysts/microphenocrysts (35-49%), have abundant microlites, and have less evolved groundmass glass compositions (69.4-73.8 wt.% SiO2). There is also evidence for crystal transfer between magma producing white and grey pumice. Thin highly evolved melt rims surround some fragmental crystals in grey pumice clasts and appear to have come from magma that produced white pumice. Furthermore, based on crystal compositions, white bands within banded pumice contain crystals originating in grey magma. Finally, only grey pumice clasts form

Geologic map of the Tetilla Peak Quadrangle, Santa Fe and Sandoval counties, New Mexico

USGS Publications Warehouse

Sawyer, D.A.; Shroba, R.R.; Minor, S.A.; Thompson, R.A.

2002-01-01

This digital geologic map summarizes all available geologic information for the Tetilla Peak quadrangle located immediately southwest of Santa Fe, New Mexico. The geologic map consists of new polygon (geologic map units) and line (contact, fault, fold axis, dike, flow contact, hachure) data, as well as point data (locations for structural measurements, geochemical and geochronologic data, geophysical soundings, and water wells). The map database has been generated at 1:24,000 scale, and provides significant new geologic information for an area of the southern Cerros del Rio volcanic field, which sits astride the boundary of the Espanola and Santo Domingo basins of the Rio Grande rift. The quadrangle includes the west part of the village of La Cienega along its eastern border and includes the southeasternmost part of the Cochiti Pueblo reservation along its northwest side. The central part of the quadrangle consists of Santa Fe National Forest and Bureau of Land Management lands, and parts of several Spanish-era land grants. Interstate 25 cuts through the southern half of the quadrangle between Santa Fe and Santo Domingo Pueblo. Canada de Santa Fe, a major river tributary to the Rio Grande, cuts through the quadrangle, but there is no dirt or paved road along the canyon bottom. A small abandoned uranium mine (the La Bajada mine) is found in the bottom of the Canada de Santa Fe about 3 km east of the La Bajada fault zone; it has been partially reclaimed. The surface geology of the Tetilla Peak quadrangle consists predominantly of a thin (1-2 m generally, locally as thick as 10? m) layer of windblown surficial deposits that has been reworked colluvially. Locally, landslide, fluvial, and pediment deposits are also important. These colluvial deposits mantle the principal bedrocks units, which are (from most to least common): (1) basalts, basanites, andesite, and trachyte of the Pliocene (2.7-2.2 Ma) Cerros del Rio volcanic field; (2) unconsolidated deposits of the Santa

Large rock avalanches in southern Perù: the Cerro Caquilluco - Cerrillos Negros rock slide - avalanche (Tacna, Tomasiri, Perù)

NASA Astrophysics Data System (ADS)

Crosta, G.; Hermanns, R. L.; Murillo, P. V.

2012-04-01

The Andean bent which coincides with the Peruvian-Chilean border region is characterised by one of the largest relief contrasts on earth with depth of the subduction trench ranging from 5000 to 6000 m below sea level and mountain tops ranging from 5500 to 6300 m a.s.l.. The western flank of the Andes is subdivided in 4 major geologic zones (i.e. Coastal Cordillera, longitudinal Basin or depression, the Precordillera or western escarpment and western Cordillera). Local relief contrasts are also pronounced due to the incision of deep canyons into several million old uplifted surfaces, preserved because of the extremely dry climate with precipitation averaging a few mm and less per year. The Lluta collapse (minimum age of 2.5 Ma; volume 26 km3) is one of the largest non-volcanic non-marine landslides on Earth and has been mapped in that area (Wörner et al., 2002). Systematic mapping in northern Chile and Southern Peru has revealed that this is not the only gigantic landslide in the area but that further landslides of similar size occurred in the area, located both along the canyon slopes and along the western escarpment of the Cordillera. This suggests that landsliding has been a major factor in controlling erosion. This contribution describes first results on mapping a giant landslide complex in southern Perù called the Cerro Caquilluco - Cerrillos Negros Tomasiri rock slide - avalanche complex. The systematic mapping we have carried out in the area is presented in a further contribution to this conference. The Cerro Caquilluco - Cerrillos Negros Tomasiri rock slide - avalanche complex affected the upper part of a SW dipping paleosurface (8° to 9°) cut by a disconnected and regular primitive drainage network organized in a series of SW trending parallel valleys. This network developed within the lower Miocene pinkish tuffaceous deposits of the Huaylillas formation, whereas the main landslide scarp lies within the conglomerates of the Upper Moquegua formation

Palynological analysis of camelid coprolites: seasonality in the use of the site Cerro Casa de Piedra 7 (Santa Cruz, Argentina)

NASA Astrophysics Data System (ADS)

Velázquez, Nadia Jimena; Burry, Lidia Susana; Fugassa, Martín Horacio; Civalero, María Teresa; Aschero, Carlos Alberto

2014-01-01

Palynological, palaeoparasitological and paleobotanical studies of coprolites found in archaeological sites from Perito Moreno National Park (47°57‧S72°05‧W) yielded information on diet, palaeoenvironment and health. These studies allowed adding evidence to the reconstruction of life history of the hunter-gatherers that inhabited Patagonia during the Holocene. We examined the season of the year when camelid Lama guanicoe coprolites (5400 ± 64 yr 14C BP to 9640 ± 190 yr 14C BP) were deposited at Cerro Casa de Piedra 7 (site CCP7). The study used palynological evidence and comparison with pollen spectra of modern feces collected during summer, fall, winter and spring of 2010. The dominant types were: pollen of Nothofagus, Empetrum rubrum, Asteraceae subfam. Asteroideae, Nassauvia, Caryophyllaceae and Poaceae; fern spores; remains of Eimeria macusaniensis; and plant remains of Poaceae, Festuca pallescens, Stipa speciosa, Armeria maritima, Gaultheria mucronata and E. rubrum. Pollen spectra of modern and fossil feces were used for multivariate analysis. Coprolites associated to fall and winter modern feces. These results and those obtained from pollen concentration values and the presence of pollen types indicators of seasonality, allowed the determination of summer, fall and winter coprolites. However, caution must be taken with the seasonality results of coprolites dated earlier than 9000 years BP since the environmental conditions differed from now. The site was probably a camelid shelter during the unfavorable seasons.

Observations of the Breakdown of Mountain Waves Over the Andes Lidar Observatory at Cerro Pachon on 8/9 July 2012

NASA Astrophysics Data System (ADS)

Hecht, J. H.; Fritts, D. C.; Wang, L.; Gelinas, L. J.; Rudy, R. J.; Walterscheid, R. L.; Taylor, M. J.; Pautet, P. D.; Smith, S.; Franke, S. J.

2018-01-01

Although mountain waves (MWs) are thought to be a ubiquitous feature of the wintertime southern Andes stratosphere, it was not known whether these waves propagated up to the mesopause region until Smith et al. (2009) confirmed their presence via airglow observations. The new Andes Lidar Observatory at Cerro Pachon in Chile provided the opportunity for a further study of these waves. Since MWs have near-zero phase speed, and zero wind lines often occur in the winter upper mesosphere (80 to 100 km altitude) region due to the reversal of the zonal mean and tidal wind, MW breakdown may routinely occur at these altitudes. Here we report on very high spatial/temporal resolution observations of the initiation of MW breakdown in the mesopause region. Because the waves are nearly stationary, the breakdown process was observed over several hours; a much longer interval than has previously been observed for any gravity wave breakdown. During the breakdown process observations were made of initial horseshoe-shaped vortices, leading to successive vortex rings, as is also commonly seen in Direct Numerical Simulations (DNS) of idealized and multiscale gravity wave breaking. Kelvin-Helmholtz instability (KHI) structures were also observed to form. Comparing the structure of observed KHI with the results of existing DNS allowed an estimate of the turbulent kinematic viscosity. This viscosity was found to be around 25 m2/s, a value larger than the nominal viscosity that is used in models.

11. Photocopy of drawing (this photograph is an 8''x 10''contact ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Photocopy of drawing (this photograph is an 8''x 10''contact print; February 7, 1989 revision of a September, 1986 as built drawing by D. Monclova, in possession of the Highway Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Santiago (sic) Channel, Route no. 2 km. 75.50, Arecibo, P.R. Bridge no. 53. No. 1 of 2. - Puente del Cano Carate, Spanning Cano Carate Channel, Arecibo, Arecibo Municipio, PR

Telescopes on Cerro Tololo & Cerro Pachon | CTIO

Science.gov Websites

Program PIA Program GO-FAAR Program Other Opportunities Tourism Visits to Tololo Astro tourism in Chile Tourism in Chile Information for travelers Visit Tololo Media Relations News Press Release Publications

Fault kinematics and depocenter evolution of oil-bearing, continental successions of the Mina del Carmen Formation (Albian) in the Golfo San Jorge basin, Argentina

NASA Astrophysics Data System (ADS)

Paredes, José Matildo; Plazibat, Silvana; Crovetto, Carolina; Stein, Julián; Cayo, Eric; Schiuma, Ariel

2013-10-01

Up to 10% of the liquid hydrocarbons of the Golfo San Jorge basin come from the Mina del Carmen Formation (Albian), an ash-dominated fluvial succession preserved in a variably integrated channel network that evolved coeval to an extensional tectonic event, poorly analyzed up to date. Fault orientation, throw distribution and kinematics of fault populations affecting the Mina del Carmen Formation were investigated using a 3D seismic dataset in the Cerro Dragón field (Eastern Sector of the Golfo San Jorge basin). Thickness maps of the seismic sub-units that integrate the Mina del Carmen Formation, named MEC-A-MEC-C in ascending order, and mapping of fluvial channels performed applying geophysical tools of visualization were integrated to the kinematical analysis of 20 main normal faults of the field. The study provides examples of changes in fault throw patterns with time, associated with faults of different orientations. The "main synrift phase" is characterized by NE-SW striking (mean Az = 49°), basement-involved normal faults that attains its maximum throw on top of the volcanic basement; this set of faults was active during deposition of the Las Heras Group and Pozo D-129 formation. A "second synrift phase" is recognized by E-W striking normal faults (mean Az = 91°) that nucleated and propagated from the Albian Mina del Carmen Formation. Fault activity was localized during deposition of the MEC-A sub-unit, but generalized during deposition of MEC-B sub-unit, producing centripetal and partially isolated depocenters. Upward decreasing in fault activity is inferred by more gradual thickness variation of MEC-C and the overlying Lower Member of Bajo Barreal Formation, evidencing passive infilling of relief associated to fault boundaries, and conformation of wider depocenters with well integrated networks of channels of larger dimensions but random orientation. Lately, the Mina del Carmen Formation was affected by the downward propagation of E-W to ESE-WNW striking

14. Photocopy of drawing (this photograph is an 8''x 10'' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. Photocopy of drawing (this photograph is an 8''x 10'' contact print; November 1, 1993 revision of a May, 1982 as built drawing by M. Villafane, in possession of the Highway System Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Perdomo Channel, Road no. P.R.2, Km. 75.60, Arecibo, P.R. no. 2 of 3. - Puente del Cano Perdomo, Route PR-2 spanning Cano Perdomo Channel, Arecibo, Arecibo Municipio, PR

3. Photocopy of drawing (this photograph is an 8''x 10'' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopy of drawing (this photograph is an 8''x 10'' contact print; February, 1989 revision of a December 11, 1973 as built drawing by A. Rivera-Cruz, in possession of the Highway System Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Rio Grande de Arecibo, Arecibo, P.R., Road no. 2, Km. 75.00 - Puente del Cano San Francisco, Spanning Cano San Francisco (Rio Grande de Arecibo), Arecibo, Arecibo Municipio, PR

15. Photocopy of drawing (this photograph is an 8''x 10'' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Photocopy of drawing (this photograph is an 8''x 10'' contact print; November 1, 1993 revision of a May, 1982 as built drawing by M. Villafane, in possession of the Highway System Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Perdomo Channel, Road no. P.R.2, Km. 75.60, Arecibo, P.R. no. 3 of 3. - Puente del Cano Perdomo, Route PR-2 spanning Cano Perdomo Channel, Arecibo, Arecibo Municipio, PR

5. Photocopy of drawing (this photograph is an 8''x 10'' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Photocopy of drawing (this photograph is an 8''x 10'' contact print; December, 1990 as built drawing by M. Villafane, in possession of the Highway System Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Rio Grande de Arecibo, Route no. 2 Km. 74.75. Arecibo, P.R. Bridge no. 44. no. 3 of 4. - Puente del Rio Grande de Arecibo, Spanning Rio Grande de Arecibo Channel, Cambalache neighborhood, Arecibo, Arecibo Municipio, PR

13. Photocopy of drawing (this photograph is an 8''x 10'' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. Photocopy of drawing (this photograph is an 8''x 10'' contact print; November 1, 1993 revision of a May, 1982 as built drawing by M. Villafane, in possession of the Highway System Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Perdomo Channel, Road no. P.R.2, Km. 75.60, Arecibo, P.R. no. 1 of 3. - Puente del Cano Perdomo, Route PR-2 spanning Cano Perdomo Channel, Arecibo, Arecibo Municipio, PR

Heterogeneous pumice populations in the 2.08-Ma Cerro Galán Ignimbrite: Implications for magma recharge and ascent preceding a large-volume silicic eruption

USGS Publications Warehouse

Wright, Heather M.; Folkes, Christopher B.; Cas, Ray A.F.; Cashman, Katharine V.

2011-01-01

Triggering mechanisms of large silicic eruptions remain a critical unsolved problem. We address this question for the ~2.08-Ma caldera-forming eruption of Cerro Galán volcano, Argentina, which produced distinct pumice populations of two colors: grey (5%) and white (95%) that we believe may hold clues to the onset of eruptive activity. We demonstrate that the color variations correspond to both textural and compositional variations between the clast types. Both pumice types have bulk compositions of high-K, high-silica dacite to low-silica rhyolite, but there are sufficient compositional differences (e.g., ~150 ppm lower Ba at equivalent SiO2 content and 0.03 wt.% higher TiO2 in white pumice than grey) to suggest that the two pumice populations are not related by simple fractionation. Trace element concentrations in crystals mimic bulk variations between clast types, with grey pumice containing elevated Ba, Cu, Pb, and Zn concentrations in both bulk samples (average Cu, Pb, and Zn concentrations are 27, 35, and 82 in grey pumice vs. 11, 19, and 60 in white pumice) and biotite phenocrysts and white pumice showing elevated Li concentrations in biotite and plagioclase phenocrysts. White and grey clasts are also texturally distinct: White pumice clasts contain abundant phenocrysts (44–57%), lack microlites, and have highly evolved groundmass glass compositions (76.4–79.6 wt.% SiO2), whereas grey pumice clasts contain a lower percentage of phenocrysts/microphenocrysts (35–49%), have abundant microlites, and have less evolved groundmass glass compositions (69.4–73.8 wt.% SiO2). There is also evidence for crystal transfer between magma producing white and grey pumice. Thin highly evolved melt rims surround some fragmental crystals in grey pumice clasts and appear to have come from magma that produced white pumice. Furthermore, based on crystal compositions, white bands within banded pumice contain crystals originating in grey magma. Finally, only grey

Acerca del moho

EPA Pesticide Factsheets

El moho forma parte del medio ambiente natural. Afuera del hogar, el moho juega un papel en la naturaleza al desintegrar materias organicas tales como las hojas que se han caido o los arboles muertos. El moho puede crecer adentro del hogar cuando las espor

Produccion Gaseosa del Cometa Halley: Erupciones Y Fotodisociacion del Radical OH

NASA Astrophysics Data System (ADS)

Silva, A. M.; Mirabel, I. F.

1990-11-01

RESUMEN:En este trabajo informamos la detecci6n de 20 erupciones en la li'nea de =18cm (1667MHz) del radical OH en el Cometa Halley.Las observaciones incluyen todos los monitoreos existentes y se extienden desde 120 dias antes del perihelio hasta 90 dias despues.Se detectan bruscos crecimientos en el flujo medido,hasta un factor 1O,seguidos por decaimientos lentos asociados con la fotodisociaci6n del OH. Se obtuvieron valores para el tiempo de vida fotoquimico del OH y del H2O basandose en el modelo desarrollado previamente por Silva(1988). Esos tiempos de vida estan de acuerdo con predicciones teoricas y con las observaciones en el Ultravioleta, y los resultados, los que son fuertemente dependientes de la velocidad heliocentrica del Coineta (variando hasta un factor 6), han sido calculados para varios rangos de velocidad entre +28 y -28 km/seg. Key wo'L :

4. Photocopy of drawing (this photograph is an 8''x 10'' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Photocopy of drawing (this photograph is an 8''x 10'' contact print; January, 1995 revision of a July 11, 1973 as built drawing by A. Rivera-Cruz, in possession of the Highway System Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Rio Grande de Arecibo, Route no. 2 Km. 74.75. Bridge no. 44. no. 2 of 4. - Puente del Rio Grande de Arecibo, Spanning Rio Grande de Arecibo Channel, Cambalache neighborhood, Arecibo, Arecibo Municipio, PR

6. Photocopy of drawing (this photograph is an 8''x 10'' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Photocopy of drawing (this photograph is an 8''x 10'' contact print; January 4, 1995 revision of a February, 1992 as built drawing by M. Villafane, in possession of the Highway System Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Rio Grande de Arecibo, Route no. 2 Km. 74.75. Arecibo, P.R. Bridge no. 44. no. 4 of 4. - Puente del Rio Grande de Arecibo, Spanning Rio Grande de Arecibo Channel, Cambalache neighborhood, Arecibo, Arecibo Municipio, PR

3. Photocopy of drawing (this photograph is an 8''x 10'' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopy of drawing (this photograph is an 8''x 10'' contact print; January, 1995 revision of a October 31, 1973 as built drawing by A. Rivera-Cruz, in possession of the Highway System Administration Office of the Puerto Rico Highway and Transportation Authority) Bridge over Rio Grande de Arecibo, Route no. 2 Arecibo Km. 74.40. Bridge no. 44 no. 1 of 4. - Puente del Rio Grande de Arecibo, Spanning Rio Grande de Arecibo Channel, Cambalache neighborhood, Arecibo, Arecibo Municipio, PR

Vigilando la Calidad del Agua de los Grandes Rios de la Nacion: El Programa NASQAN del Rio Grande (Rio Bravo del Norte)

USGS Publications Warehouse

Lurry, Dee L.; Reutter, David C.; Wells, Frank C.; Rivera, M.C.; Munoz, A.

1998-01-01

La Oficina del Estudio Geologico de los Estados Unidos (U.S. Geological Survey, 0 USGS) ha monitoreado la calidad del agua de la cuenca del Rio Grande (Rio Bravo del Norte) desde 1995 como parte de la rediseiiada Red Nacional para Contabilizar la Calidad del Agua de los Rios (National Stream Quality Accounting Network, o NASOAN) (Hooper and others, 1997). EI programa NASOAN fue diseiiado para caracterizar las concentraciones y el transporte de sedimento y constituyentes quimicos seleccionados, encontrados en los grandes rios de los Estados Unidos - incluyendo el Misisipi, el Colorado y el Columbia, ademas del Rio Grande. En estas cuatro cuencas, el USGS opera actualmente (1998) una red de 40 puntos de muestreo pertenecientes a NASOAN, con un enfasis en cuantificar el flujo en masa (la cantidad de material que pasa por la estacion, expresado en toneladas por dial para cada constituyente. Aplicacando un enfoque consistente, basado en la cuantificacion de flujos en la cuenca del Rio Grande, el programa NASOAN esta generando la informacion necesaria para identificar fuentes regionales de diversos contaminantes, incluyendo sustancias qui micas agricolas y trazas elementos en la cuenca. EI efecto de las grandes reservas en el Rio Grande se puede observar segun los flujos de constituyentes discurren a 10 largo del rio. EI analisis de los flujos de constituyentes a escala de la cuenca proveera los medios para evaluar la influencia de la actividad humana sobre las condiciones de calidad del agua del Rio Grande.

Mineralogy, structural control and age of the Incachule Sb epithermal veins, the Cerro Aguas Calientes collapse caldera, Central Puna

NASA Astrophysics Data System (ADS)

Salado Paz, Natalia; Petrinovic, Iván; Do Campo, Margarita; Brod, José Affonso; Nieto, Fernando; da Silva Souza, Valmir; Wemmer, Klauss; Payrola, Patricio; Ventura, Roberto

2018-03-01

The Incachule Sb epithermal veins is located near to the N-E rim of the Cerro Aguas Calientes collapse caldera (17.5-10.8 Ma), in the geologic province of Puna, Salta- Argentina. It is hosted in Miocene felsic volcanic rocks with continental arc signature. The district includes twelve vein systems with mineralization of Sb occurring in hydrothermal breccias and stockwork. The veins are composed of quartz-sulfide with pyrite, stibnite and arsenopyrite. All around the veins, wall rocks are variably altered to clay minerals and sulfates in an area of around 2.5 km wide by more than 7 km long. The hydrothermal alterations recognized are: silicic, phyllic and argillic. The veins are characterized by high contents of Sb, As, and Tl and intermediate contents of Pb-Zn-Cu, and traces of Ag and Au. Homogenization and ice-melting temperatures of fluid inclusions vary from 125 °C to 189 °C and -2.4 °C to -0.8 °C. The isotopic data indicated a range of δ34S -3.04‰ to +0.72‰ consistent with a magmatic source for sulfur. We present the firsts K-Ar ages for hydrothermal illite/smectite mixed layers (I/SR1, 60% illite layers) and illite that constrain the age of the ore deposit (8.5-6.7 ± 0.2 Ma). The data shown here, let characterized the Incachule district as a shallow low sulfidation epithermal system hosted in a collapse caldera. Our data also indicate that mineralization is structurally controlled by a fault system related to the 10.3 Ma collapse of Aguas Calientes caldera. The interpreted local stress field is consistent with the regional one.

Rock-magnetism and ore microscopy of the magnetite-apatite ore deposit from Cerro de Mercado, Mexico

NASA Astrophysics Data System (ADS)

Alva-Valdivia, L. M.; Goguitchaichvili, A.; Urrutia-Fucugauchi, J.; Caballero-Miranda, C.; Vivallo, W.

2001-03-01

Rock-magnetic and microscopic studies of the iron ores and associated igneous rocks in the Cerro de Mercado, Mexico, were carried out to determine the magnetic mineralogy and origin of natural remanent magnetization (NRM), related to the thermo-chemical processes due to hydrothermalism. Chemical remanent magnetization (CRM) seems to be present in most of investigated ore and wall rock samples, replacing completely or partially an original thermoremanent magnetization (TRM). Magnetite (or Ti-poor titanomagnetite) and hematite are commonly found in the ores. Although hematite may carry a stable CRM, no secondary components are detected above 580°, which probably attests that oxidation occurred soon enough after the extrusion and cooling of the ore-bearing magma. NRM polarities for most of the studied units are reverse. There is some scatter in the cleaned remanence directions of the ores, which may result from physical movement of the ores during faulting or mining, or from perturbation of the ambient field during remanence acquisition by inhomogeneous internal fields within these strongly magnetic ore deposits. The microscopy study under reflected light shows that the magnetic carriers are mainly titanomagnetite, with significant amounts of ilmenite-hematite minerals, and goethite-limonite resulting from alteration processes. Magmatic titanomagnetites, which are found in igneous rocks, show trellis, sandwich, and composite textures, which are compatible with high temperature (deuteric) oxy-exsolution processes. Hydrothermal alteration in ore deposits is mainly indicated by martitization in oxide minerals. Grain sizes range from a few microns to >100 mm, and possible magnetic state from single to multidomain, in agreement with hysteresis measurements. Thermal spectra, continuous susceptibility measurements, and IRM (isothermal remanent magnetization) acquisition suggest a predominance of spinels as magnetic carriers, most probably titanomagnetites with low

The flow dynamics of an extremely large volume pyroclastic flow, the 2.08-Ma Cerro Galán Ignimbrite, NW Argentina, and comparison with other flow types

USGS Publications Warehouse

Cas, Ray A.F.; Wright, Heather M.; Folkes, Christopher B.; Lesti, Chiara; Porreca, Massimiliano; Giordano, Guido; Viramonte, Jose G.

2011-01-01

The 2.08-Ma Cerro Galán Ignimbrite (CGI) represents a >630-km3 dense rock equivalent (VEI 8) eruption from the long-lived Cerro Galán magma system (∼6 Ma). It is a crystal-rich (35–60%), pumice (<10% generally) and lithic-poor (<5% generally) rhyodacitic ignimbrite, lacking a preceding plinian fallout deposit. The CGI is preserved up to 80 km from the structural margins of the caldera, but almost certainly was deposited up to 100 km from the caldera in some places. Only one emplacement unit is preserved in proximal to medial settings and in most distal settings, suggesting constant flow conditions, but where the pyroclastic flow moved into a palaeotopography of substantial valleys and ridges, it interacted with valley walls, resulting in flow instabilities that generated multiple depositional units, often separated by pyroclastic surge deposits. The CGI preserves a widespread sub-horizontal fabric, defined by aligned elongate pumice and lithic clasts, and minerals (e.g. biotite). A sub-horizontal anisotropy of magnetic susceptibility fabric is defined by minute magnetic minerals in all localities where it has been analysed. The CGI is poor in both vent-derived (‘accessory’) lithics and locally derived lithics from the ground surface (‘accidental’) lithics. Locally derived lithics are small (<20 cm) and were not transported far from source points. All data suggest that the pyroclastic flow system producing the CGI was characterised throughout by high sedimentation rates, resulting from high particle concentration and suppressed turbulence at the depositional boundary layer, despite being a low aspect ratio ignimbrite. Based on these features, we question whether high velocity and momentum are necessary to account for extensive flow mobility. It is proposed that the CGI was deposited by a pyroclastic flow system that developed a substantial, high particle concentration granular under-flow, which flowed with suppressed turbulence. High particle

Paleoparasitological finding of eggs of nematodes in rodent coprolites dated at the early Holocene from the archaeological site Cerro Casa de Piedra 7, Santa Cruz, Argentina.

PubMed

Sardella, N H; Fugassa, M H

2011-12-01

The aim of the present study was to examine the parasite remains present in rodent coprolites collected from the archaeological site Cerro Casa de Piedra 7 (CCP7), located in the Perito Moreno National Park (47°57'S, 72°05'W), Santa Cruz Province, Argentina. Eight coprolites obtained from the layer 17, dated at 10,620 ± 40 to 9,390 ± 40 yr B.P., were examined for parasites. Feces were processed whole, rehydrated, homogenized, subjected to spontaneous sedimentation, and examined via light microscopy. Eggs of parasites were measured and photographed. Seven of 8 coprolites possessed 199 eggs of 2, probably new, species of nematodes, including 43 eggs of Heteroxynema sp. Hall, 1916 (Cavioxyura sp. Quentin, 1975) (Oxyurida, Heteroxynematidae), and 156 eggs of Trichuris sp. Roederer, 1761 (Trichinellida, Trichuridae). Heteroxynema sp. is cited for the first time from ancient material worldwide. The finding of Trichuris spp. in both rodents and other host samples from the area under study is indicative of the stability of the biological and environmental conditions for this nematode genus to establish in the Patagonian Early Holocene. The rodent host was assigned to an unknown species of Caviomorpha (Hystricognathi) that lived during the Pleistocenic transition in Patagonia.

Radio-Observaciones del OH EN la Coma del Cometa Halley Desde EL Hemisferio Sur

NASA Astrophysics Data System (ADS)

Silva, A. M.; Bajaja, E.; Morras, R.; Cersosimo, J. C.; Martin, M. C.; Arnal, E. M.; Poppel, W. G. L.; Colomb, F. R.; Mazzaro, J.; Olalde, J. C.; Boriakoff, V.; Mirabel, I. F.

1987-05-01

Se utilizó una antena de 30 metros del Instituto Argentino de Radioastronomía para observaciones diarias Cf ebrero a abril de 1986) de la transición en 1667 MHz ( λ = 18 cm) del OH en la coma del cometa Halley. De las observaciones realizadas se concluye: 1) El número promedio de moléculas de OH en la coma durante 37 días de observación fue de (8.9±3.5)x1034 moléculas, lo que implica una tasa de producción promedio de OH de 1.8x1029 moléculas seg-1 y consecuentemente una pérdida de masa promedio de 17±6 toneladas seg-1 . Este valor está de acuerdo con las mediciones realizadas por las sondas Vega y Giotto. 2) El monitoreo desde el lAR revela la existencia de variaciones bruscas en los flujos de absorción del OH. Estas variaciones son consistentes con los modelos que representan la producción gaseosa a partir de ejecciones y/o desprendimientos discretos de materia congelada del núcleo. 3) Las variaciones en la densidad de flujo son consistentes con las estimaciones de los tiem- pos de vida medios del H2O y del OH en presencia del campo de radiación solar. 4) Se encuentra una correlación entre la intensidad del flujo absorbido y anisotropías en Ia dinamica de la coma.

The ~ 2500 yr B.P. Chicoral non-cohesive debris flow from Cerro Machín Volcano, Colombia

NASA Astrophysics Data System (ADS)

Murcia, H. F.; Hurtado, B. O.; Cortés, G. P.; Macías, J. L.; Cepeda, H.

2008-04-01

Cerro Machín Volcano (CMV) is located in the central part of the Colombian Andes (2750 m asl), 150 km southwest of Bogotá. It is considered the most dangerous active volcano of Colombia. CMV has experienced at least six major explosive eruptions during the last 5000 years. These eruptions have emplaced many types of pyroclastic deposits with associated lahars that have traveled more than 100 km. One of these lahars is called Chicoral Debris Flow Deposit (DFD2). This deposit is exposed as discontinuous terraces (3-20 m thick) along the Coello and Magdalena rivers up to 109 km from the source. The DFD2 covers a minimum area of 62 km 2 and has a minimum volume of 0.57 km 3. It comprises two dacite-rich volcaniclastic units. Grain-size analysis reveals that the matrix content and sorting increase with distance while the average grain size decreases. The clay content of the DFD2 matrix is approximately 1%, thus categorizing it as a non-cohesive debris flow. Radiocarbon dates obtained from underlying and overlying paleosols yielded ages of 2505 + 65 and 1640 + 45 yr B.P., respectively. These dates suggest that DFD2 is related to the ~ 2600 yr B.P. El Guaico eruption of CMV. This eruption produced a block-and-ash flow that filled and blocked the Toche River up to 5 km from the volcano. Subsequent remobilization of this loose material by runoff water generated a massive debris flow that traveled 91 km along the Toche and Coello rivers and continued across the Espinal Alluvial Fan debouching into the Magdalena River where it continued another 18 km prior to its transformation into a sediment-laden flow. Because the last eruption of the volcano occurred ca. 900 years ago, no historic activity of CMV is known among inhabitants of the region. Hence the region has developed without awareness of volcanic hazards. Therefore an assessment of volcanic hazards is essential for understanding and evaluating the vulnerability and risk to which people are exposed in case of a future

Espectroscopia del Cometa Halley

NASA Astrophysics Data System (ADS)

Naranjo, O.; Fuenmayor, F.; Ferrin, L.; Bulka, P.; Mendoza, C.

1987-05-01

Se reportan observaciones espectroscópicas del cometa Halley. Los espectros fueron tomados usando el espectrógrafo del telescopio reflector de 1 metro del Observatorio Nacional de Venezuela. Se utilizó óptica azul, con una red de difracción de 600 lineas/min, obteniéndose una dispersión de 74.2 A/mm y una resolución de 2.5 A, en el rango espectral de 3500 a 6500 A. Seis placas fueron tomadas con emulsión IIa-O y dos con IIa-D. Los tiempos de exposición fueron entre 10 y 150 minutos. El cometa se encontraba entre 0.70 y 1.04 UA del Sol, y entre 1.28 y 0.73 UA de la Tierra. Las emisiones más prominentes en el espectro, son las del CN, C2, y C3. Otras emisiones detectadas corresponden a CH, NH2 y Na. Los espectros muestran un fuerte continuo, indicando un contenido significativo de polvo. Se detectó mayor intensidad del contínuo, en la dirección anti solar, lo cual es evidencia de la cola de polvo.

Intertextual Sexual Politics: Illness and Desire in Enrique Gomez Carrillo's "Del amor", "del dolor y del vicio" and Aurora Caceres's "La rosa muerta"

ERIC Educational Resources Information Center

LaGreca, Nancy

2012-01-01

This study explores the intertextuality between Aurora Caceres's "La rosa muerta" (1914) and the novel "Del amor, del dolor y del vicio" (1898) by her ex-husband, Enrique Gomez Carrillo. Caceres strategically mentions Gomez Carrillo's novel in "La rosa muerta" to invite a reading of her work in dialogue with his. Both narratives follow the sexual…

Area Handbook Series: Uruguay, A Country Study.

DTIC Science & Technology

1990-12-01

Artigas, Cerro Largo , Durazno, Flores, Florida, Lavalleja, Rivera, Salto, Tacua- remb6, and Treinta y Tres and the eastern halves of Paysand6, Rio...19 SAN JOSt PAYSANDI RIVERA SALTO 8 SORIANO ARTIGAS CERRO LARGO FLORIDA 6 LAVALLEJA ROCHA DURAZNO FLORES RIO NEGRO 5 TACUAREMB6 TREINTA Y TRES 1 10...industrialization. Least developed were the northern ranching departments along the Brazilian border- Artigas, Rivera, and Cerro Largo -and also Tacuaremb6

Effect of artificial feeders on pollen loads of the hummingbirds of Cerro de la Muerte, Costa Rica.

PubMed

Avalos, Gerardo; Soto, Alejandra; Alfaro, Willy

2012-03-01

Although sugar-water feeders are commonly used by enthusiasts to attract hummingbirds, little is known about how they affect hummingbird behavior and flower use. We studied the highland hummingbird assemblage of Cerro de La Muerte, Costa Rica, both at a site with permanent feeders (La Georgina Restaurant) and further from it. We examined how feeder use and monopolization affected seasonal changes in pollen loads during four sampling periods, including dry and wet seasons, from 2003-2005. We expected that species monopolizing the feeders would carry little or no pollen whatsoever, and would have pollen loads characterized by low floral diversity, in contrast with species less dependent on feeders. We obtained pollen samples from 183 individuals of four hummingbird species captured around the feeders using mist nets, which were compared with a pollen reference collection of plants with a pollination syndrome by hummingbirds. The same methods were implemented at a site 3km away from the feeders. Feeder usage was quantified by counting the number of times hummingbirds drank from the feeders in periods of 4min separated by 1min. The effects of hummingbird species and season on pollen load categories were assessed using a nominal logistic regression. The alpha species at the site, the Fiery-throated Hummingbird (Panterpe insignis), dominated the feeders during the dry season. Meanwhile, in the wet season, feeder usage was more evenly distributed across species, with the exception of the Volcano Hummingbird, Selasphorus flammula, which occupies the last place in the dominance hierarchy. Pollen loads of hummingbirds captured near feeders were low in abundance (more than 50% of captured individuals had zero or low pollen loads), and low in species richness (96% of the hummingbirds with pollen from only one plant genus, Centropogon). Overall pollen loads increased during the dry season coinciding with peaks in flower availability, although the majority of captured

Models of Metabolic Community Structure in Martian Habitable Environments: Constraints from a Terrestrial Analog Acid-Sulfate Fumarole Environment, Cerro Negro Volcano, Nicaragua

NASA Astrophysics Data System (ADS)

Rogers, K. L.; McCollom, T. M.; Hynek, B. M.

2014-12-01

Microbial habitability in extreme environments on Earth is described by microscale geochemical conditions that constrain metabolic niches in concert with long-term habitat stability that is governed by dynamic geologic processes. Using terrestrial analogs to identify habitable martian environments requires correlating microscale geochemical constraints with reconstructions of past martian environments that are based on global-scale observations. While past martian environments can be characterized by primary parameters (e.g. pH, redox, mineralogy, thermal history), microbial habitability on Earth is a complex function of both primary and derived parameters (e.g. metabolic reaction energetics, chemical & thermal gradients, flow dynamics). In recent years we have been investigating acid-sulfate fumaroles at the Mars analog site, Cerro Negro Volcano, Nicaragua, where habitability is constrained by steep thermal gradients, spatially- and temporally-variable vent dynamics, and limited water and nutrient availability. The most common niche identified thus far is found in fumaroles that host mixed photosynthetic and chemosynthetic endolithic microbial communities. One such endolith is dominated by acidic red algae (Cyanidiales), aerobic bacterial heterotrophs (Ktedonobacteria), and archaeal thermoacidophiles (Hyperthermus, Caldisphaera, and Thermofilum). An analysis of the metabolic structure suggests that primary production by the red algae supports the growth of heterotrophic thermoacidophiles. Diversification among the chemoheterotrophs with respect to temperature and oxygen tolerance suggests community adaptation to environmental gradients or variable venting dynamics. Furthermore, individual cells within the endolith are silica-encrusted, providing the possibility for biosignature formation and preservation. Putative hydrothermal environments on early Mars with similar conditions could have supported endolithic communities with comparable metabolic strategies. Even

El Planetario Móvil de la Municipalidad de la ciudad de Córdoba

NASA Astrophysics Data System (ADS)

Suárez, F. E.; Campos, M.; Goldes, G. V.; Carranza, G. J.; Romero, R.; Juri, H. O.

Se describen las características y operatoria del nuevo Planetario Móvil. Se trata de un equipamiento de propiedad de la Municipalidad de la Ciudad de Córdoba que es operado por personal y en el predio de la Universidad, en virtud de un convenio suscripto entre ambas instituciones. El planetario consta de una cúpula inflable y de un proyector con programas alternativos que incluyen temas de astronomía, geografía, biología y medio ambiente, entre otros. En la actualidad opera en las instalaciones del Pabellón Argentina de la Ciudad Universitaria y recibe delegaciones escolares de todo el territorio provincial. El Planetario Móvil es parte de un proyecto más amplio de divulgación científica en el cual interactúan la Universidad y el Municipio.

33 CFR 80.1118 - Marina Del Rey, CA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn from Marina Del Rey Breakwater South Light 1 to Marina Del Rey Light 4. (b) A line drawn from Marina Del Rey... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Marina Del Rey, CA. 80.1118...

33 CFR 80.1118 - Marina Del Rey, CA.

Code of Federal Regulations, 2012 CFR

2012-07-01

... NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn from Marina Del Rey Breakwater South Light 1 to Marina Del Rey Light 4. (b) A line drawn from Marina Del Rey... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Marina Del Rey, CA. 80.1118...

33 CFR 80.1118 - Marina Del Rey, CA.

Code of Federal Regulations, 2013 CFR

2013-07-01

... NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn from Marina Del Rey Breakwater South Light 1 to Marina Del Rey Light 4. (b) A line drawn from Marina Del Rey... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Marina Del Rey, CA. 80.1118...

33 CFR 80.1118 - Marina Del Rey, CA.

Code of Federal Regulations, 2011 CFR

2011-07-01

... NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn from Marina Del Rey Breakwater South Light 1 to Marina Del Rey Light 4. (b) A line drawn from Marina Del Rey... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Marina Del Rey, CA. 80.1118...

33 CFR 80.1118 - Marina Del Rey, CA.

Code of Federal Regulations, 2014 CFR

2014-07-01

... NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1118 Marina Del Rey, CA. (a) A line drawn from Marina Del Rey Breakwater South Light 1 to Marina Del Rey Light 4. (b) A line drawn from Marina Del Rey... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Marina Del Rey, CA. 80.1118...

Measurements of downwelling far-infrared radiance during the RHUBC-II campaign at Cerro Toco, Chile and comparisons with line-by-line radiative transfer calculations

NASA Astrophysics Data System (ADS)

Mast, Jeffrey C.; Mlynczak, Martin G.; Cageao, Richard P.; Kratz, David P.; Latvakoski, Harri; Johnson, David G.; Turner, David D.; Mlawer, Eli J.

2017-09-01

Downwelling radiances at the Earth's surface measured by the Far-Infrared Spectroscopy of the Troposphere (FIRST) instrument in an environment with integrated precipitable water (IPW) as low as 0.03 cm are compared with calculated spectra in the far-infrared and mid-infrared. FIRST (a Fourier transform spectrometer) was deployed from August through October 2009 at 5.38 km MSL on Cerro Toco, a mountain in the Atacama Desert of Chile. There FIRST took part in the Radiative Heating in Unexplored Bands Campaign Part 2 (RHUBC-II), the goal of which is the assessment of water vapor spectroscopy. Radiosonde water vapor and temperature vertical profiles are input into the Atmospheric and Environmental Research (AER) Line-by-Line Radiative Transfer Model (LBLRTM) to compute modeled radiances. The LBLRTM minus FIRST residual spectrum is calculated to assess agreement. Uncertainties (1-σ) in both the measured and modeled radiances are also determined. Measured and modeled radiances nearly all agree to within combined (total) uncertainties. Features exceeding uncertainties can be corrected into the combined uncertainty by increasing water vapor and model continuum absorption, however this may not be necessary due to 1-σ uncertainties (68% confidence). Furthermore, the uncertainty in the measurement-model residual is very large and no additional information on the adequacy of current water vapor spectral line or continuum absorption parameters may be derived. Similar future experiments in similarly cold and dry environments will require absolute accuracy of 0.1% of a 273 K blackbody in radiance and water vapor accuracy of ∼3% in the profile layers contributing to downwelling radiance at the surface.

Manual del McVCO 1999

USGS Publications Warehouse

McChesney, P.J.

1999-01-01

El McVCO es un generador de frecuencias basado en un microcontrolador que reemplaza al oscilador controlado por voltaje (VCO) utilizado en telemetría analógica de datos sísmicas. Acepta señales de baja potencia desde un sismómetro y produce una señal subportadora modulada en frecuencia adecuada para enlaces telefónicos o vía radio a un lugar remoto de recolección de datos. La frecuencia de la subportadora y la ganancia pueden ser seleccionadas mediante un interruptor. Tiene la opción de poder operar con dos canales para la observación con ganancia alta y baja. El McVCO fue diseñado con el propósito de mejorar la telemetría analógica de las señales dentro de la Pacific Northwest Seismograph Network (PNSN) (Red Sismográfica del Noroeste del Pacífico). Su desarrollo recibió el respaldo del Programa de Geofísica de la Universidad de Washington y del "Volcano Hazards and Earthquake Hazards programs of the United States Geological Survey (USGS) (Programa de Investigaciones de Riesgos Volcánicos y Programa de Investigaciones de Riesgos Sísmicos de los EEUU). Cientos de instrumentos se han construido e instalado. Además de utilizarlo el PNSN, el McVCO es usado por el Observatorio Vulcanológico de Alaska para monitorear los volcanes aleutianos y por el USGS Volcano Disaster Assistance Program (Programa de Ayuda en las Catástrofes Volcánicas del USGS) para responder a crisis volcánicas en otros países. Este manual cubre el funcionamiento del McVCO, es una referencia técnica para aquellos que necesitan saber con más detalle cómo funciona el McVCO, y cubre una serie de temas que requieren un trato explícito o que derivan del despliegue del instrumento.

Ácaros del mango

USDA-ARS?s Scientific Manuscript database

Los ácaros constituyen un grupo abundante y diverso que ocupa diferentes hábitats en árboles frutales y la estructura y disposición del follaje y ramas del mango, contribuyen significativamente a que se presente gran diversidad de ácaros benéficos y dañinos asociados a esta especie frutal. En Colomb...

Eruptive history of the youngest Mexican Shield and Mexico's most voluminous Holocene eruption: Cerro El Metate

NASA Astrophysics Data System (ADS)

Oryaëlle Chevrel, Magdalena; Guilbaud, Marie-Noelle; Siebe, Claus

2016-04-01

Small to medium-sized shield volcanoes are an important component of many volcanic fields on Earth. The Trans-Mexican Volcanic Belt, one of the most complex and active continental arcs worldwide, displays a large number of such medium-sized volcanoes. In particular the Michoacán-Guanajuato Volcanic Field (MGVF) situated in central Mexico, is the largest monogenetic volcanic field in the world and includes more than 1000 scoria cones and about four hundred medium-sized volcanoes, also known as Mexican shields. The Mexican shields nevertheless represent nearly 70% of the total volume erupted since 1 Ma and hence played a considerable role in the formation of the MGVF. However, the source, storage, and transport as well as the physical properties (density, viscosity, volatile content, etc.) of the magmas involved in these eruptions remain poorly constrained. Here, we focus on Cerro El Metate, the youngest monogenetic andesite shield volcano of the field. New C14 dates for the eruption yield a young age (~AD 1250), which briefly precedes the initial rise of the Tarascan Empire (AD 1350-1521) in this region. This volcano has a minimum volume of ~9.2 km3 DRE, and its viscous lava flows were emplaced during a single eruption over a period of ~35 years covering an area of 103 km2. By volume, this is certainly the largest eruption during the Holocene in Mexico, and it is the largest andesitic effusive eruption known worldwide for this period. Such a large volume of lava erupted in a relatively short time had a significant impact on the environment (modification of the hydrological network, forest fires, etc.), and hence, nearby human populations probably had to migrate. Its eruptive history was reconstructed through detailed mapping, and geochemical and rheological analyses of its thick hornblende-bearing andesitic flows. Early and late flows have distinct morphologies, chemical and mineralogical compositions, and isotopic signatures which show that these lavas were fed by

Structure of the Wagner Basin in the Northern Gulf of California From Interpretation of Seismic Reflexion Data

NASA Astrophysics Data System (ADS)

Gonzalez, M.; Aguilar, C.; Martin, A.

2007-05-01

The northern Gulf of California straddles the transition in the style of deformation along the Pacific-North America plate boundary, from distributed deformation in the Upper Delfin and Wagner basins to localized dextral shear along the Cerro Prieto transform fault. Processing and interpretation of industry seismic data adquired by Petroleos Mexicanos (PEMEX) allow us to map the main fault structures and depocenters in the Wagner basin and to unravel the way strain is transferred northward into the Cerro Prieto fault system. Seismic data records from 0.5 to 5 TWTT. Data stacking and time-migration were performed using semblance coefficient method. Subsidence in the Wagner basin is controlled by two large N-S trending sub-parallel faults that intersect the NNW-trending Cerro Prieto transform fault. The Wagner fault bounds the eastern margin of the basin for more than 75 km. This fault dips ~50° to the west (up to 2 seconds) with distinctive reflectors displaced more than 1 km across the fault zone. The strata define a fanning pattern towards the Wagner fault. Northward the Wagner fault intersects the Cerro Prieto fault at 130° on map view and one depocenter of the Wagner basin bends to the NW adjacent to the Cerro Prieto fault zone. The eastern boundary of the modern depocenter is the Consag fault, which extends over 100 km in a N-S direction with an average dip of ~50° (up to 2s) to the east. The northern segment of the Consag fault bends 25° and intersects the Cerro Prieto fault zone at an angle of 110° on map view. The acoustic basement was not imaged in the northwest, but the stratigraphic succession increases its thickness towards the depocenter of the Wagner basin. Another important structure is El Chinero fault, which runs parallel to the Consag fault along 60 km and possibly intersects the Cerro Prieto fault to the north beneath the delta of the Colorado River. El Chinero fault dips at low-angle (~30°) to the east and has a vertical offset of about 0

Torres del Paine National Park

NASA Image and Video Library

2017-12-08

Grinding glaciers and granite peaks mingle in Chile’s Torres del Paine National Park. The Advanced Land Imager (ALI) on NASA’s Earth Observing-1 (EO-1) satellite captured this summertime image of the park on January 21, 2013. This image shows just a portion of the park, including Grey Glacier and the mountain range of Cordillera del Paine. The rivers of glacial ice in Torres del Paine National Park grind over bedrock, turning some of that rock to dust. Many of the glaciers terminate in freshwater lakes, which are rich with glacial flour that colors them brown to turquoise. Skinny rivers connect some of the lakes to each other (image upper and lower right). Cordillera del Paine rises between some of the wide glacial valleys. The compact mountain range is a combination of soaring peaks and small glaciers, most notably the Torres del Paine (Towers of Paine), three closely spaced peaks emblematic of the mountain range and the larger park. By human standards, the mountains of Cordillera del Paine are quite old. But compared to the Rocky Mountains (70 million years old), and the Appalachians (about 480 million years), the Cordillera del Paine are very young—only about 12 million years old. A study published in 2008 described how scientists used zircon crystals to estimate the age of Cordillera del Paine. The authors concluded that the mountain range was built in three pulses, creating a granite laccolith, or dome-shaped feature, more than 2,000 meters (7,000 feet) thick. NASA Earth Observatory image created by Jesse Allen and Robert Simmon, using Advanced Land Imager data from the NASA EO-1 team. Caption by Michon Scott. Instrument: EO-1 - ALI View more info: earthobservatory.nasa.gov/IOTD/view.php?id=80266 Credit: NASA Earth Observatory NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA�

The Springhill Formation (Jurassic-Cretaceous) as a potential low enthalpy geothermal reservoir in the Cerro Sombrero area, Magallanes Basin, Chile.

NASA Astrophysics Data System (ADS)

Lagarrigue, S. C.; Elgueta, S.; Arancibia, G.; Morata, D.; Sanchez, J.; Rojas, L.

2017-12-01

Low enthalpy geothermal energy technologies are being developed around the world as part of policies to replace the use of conventional sources of energy by renewable ones. The reuse of abandoned oil and gas wells in sedimentary basins, whose reservoirs are saturated with water at temperatures above 120°C, is of increasing interest due to the low initial cost.In Chile, interest in applying this technology is focused on the Magallanes Basin (Austral Basin in Argentina) in the extreme south of the country, where important hydrocarbon deposits have been exploited for more than six decades with more than 3,500 wells drilled to depths of over 4,000m. Hydrocarbons have been extracted mainly from the Upper Jurassic to lowermost Cretaceous Springhill Formation, which includes sandstone lithofacies with porosities of 12% to 19% and permeability of 10mD and 1100mD. This formation has been drilled mainly at depths of 1500m to 3000m, the estimated geothermal gradient in the zone is 4.9 °C/100m with well bottom temperature measurements oscillating between 60° and 170°C, sufficient for district heating, and even, electricity generation by means of ORC technologies.To understand in detail the behavior and distribution of the different lithofacies of the Springhill Formation in the Sombrero Oil and Gas Field, sedimentological and geological 3D models have been generated from existing well logs and seismic data. To comprehend the quality of the reservoirs on the other hand, many petrophysical studies of drill core samples representative of the different lithofacies, complemented by electric well log interpretations, were carried out. Results confirm the existence of at least two quartz-rich sandstone lithofacies as potential geothermal reservoirs. In the principal settlement in this area, Cerro Sombrero township (1,800 population), the annual average temperature is 6.4°C, requiring constant domestic heating which, at present comes exclusively from natural gas. The study shows

44 CFR 295.40 - Scope.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Scope. 295.40 Section 295.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Dispute Resolution § 295.40 Scope. This...

44 CFR 295.40 - Scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Scope. 295.40 Section 295.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Dispute Resolution § 295.40 Scope. This...

44 CFR 295.40 - Scope.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Scope. 295.40 Section 295.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Dispute Resolution § 295.40 Scope. This...

44 CFR 295.40 - Scope.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Scope. 295.40 Section 295.40 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE Dispute Resolution § 295.40 Scope. This...

Efectos combinados de la ampliación de la atención primaria de salud y de las transferencias condicionadas de dinero en efectivo sobre la mortalidad infantil en Brasil, 1998–2010*

PubMed Central

Guanais, Frederico C.

2015-01-01

Objetivos. Examiné los efectos combinados del acceso a la atención primaria mediante el Programa de Salud Familiar (PSF) y las transferencias condicionadas de dinero en efectivo del Programa Bolsa Familia (PBF) sobre la mortalidad infantil posneonatal (MIPN) en Brasil. Métodos. Empleé un análisis ecológico longitudinal usando datos en panel de 4 583 municipios brasileños de 1998 al 2010, con 54 253 observaciones en total. Estimé modelos de regresión de efectos fijos por mínimos cuadrados ordinarios, con la tasa de MIPN como la variable dependiente y el PSF, el PBF y sus interacciones como las principales variables independientes de interés. Resultados. La asociación de una mayor cobertura del PSF con una menor tasa de MIPN se volvió más fuerte conforme aumentaba la cobertura del PBF. En los promedios de todas las demás variables, cuando la cobertura de PBF era 25%, la MIPN predicha fue 5,24 (intervalo de confianza [IC] de 95% = 4,95, 5,53) para una cobertura del PSF de 0%, y de 3,54 (IC de 95% = 2,77, 4,31) para una cobertura del PSF de 100%. Cuando la cobertura del PBF era de 60%, la MIPN predicha fue 4,65 (IC de 95% = 4,36, 4,94) para una cobertura del PSF de 0%, y de 1,38 (IC de 95% = 0,88, 1,89) para una cobertura del PSF de 100%. Conclusiones. El efecto del PSF depende de la ampliación del PBF. Para las poblaciones empobrecidas y subatendidas, la combinación de intervenciones tanto del lado de la oferta como del lado de la demanda podría ser necesaria para mejorar los resultados en salud.

VizieR Online Data Catalog: BVIc light curves of 57 Cepheids (Berdnikov+,

NASA Astrophysics Data System (ADS)

Berdnikov, L. N.; Kniazev, A. Yu.; Sefako, R.; Kravtsov, V. V.; Zhujko, S. V.

2014-04-01

In 2008-2013, we obtained 11333 CCD BV Ic frames for 57 Cepheids from the General Catalogue of Variable Stars. We performed our observations with the 76-cm telescope of the South AfricanAstronomicalObservatory (SAAO, South Africa) and the 40-cm telescope of the Cerro Armazones Astronomical Observatory of the Universidad Catolica del Norte (OCA, Chile) using the SBIG ST-10XME CCD camera. The tables of observations, the plots of light curves, and the current light elements are presented. Comparison of our light curves with those constructed from photoelectric observations shows that the differences between their mean magnitudes exceed 0.05mag in 20% of the cases. This suggests the necessity of performing CCD observations for all Cepheids. (2 data files).

CCD BVI c observations of Cepheids

NASA Astrophysics Data System (ADS)

Berdnikov, L. N.; Kniazev, A. Yu.; Sefako, R.; Kravtsov, V. V.; Zhujko, S. V.

2014-02-01

In 2008-2013, we obtained 11333 CCD BVI c frames for 57 Cepheids from the General Catalogue of Variable Stars. We performed our observations with the 76-cm telescope of the South African Astronomical Observatory (SAAO, South Africa) and the 40-cm telescope of the Cerro Armazones Astronomical Observatory of the Universidad Católica del Norte (OCA, Chile) using the SBIG ST-10XME CCD camera. The tables of observations, the plots of light curves, and the current light elements are presented. Comparison of our light curves with those constructed from photoelectric observations shows that the differences between their mean magnitudes exceed 0ṃ05 in 20% of the cases. This suggests the necessity of performing CCD observations for all Cepheids.

Tezacaftor/Ivacaftor in Subjects with Cystic Fibrosis and F508del/F508del-CFTR or F508del/G551D-CFTR.

PubMed

Donaldson, Scott H; Pilewski, Joseph M; Griese, Matthias; Cooke, Jon; Viswanathan, Lakshmi; Tullis, Elizabeth; Davies, Jane C; Lekstrom-Himes, Julie A; Wang, Linda T

2018-01-15

Tezacaftor (formerly VX-661) is an investigational small molecule that improves processing and trafficking of the cystic fibrosis transmembrane conductance regulator (CFTR) in vitro, and improves CFTR function alone and in combination with ivacaftor. To evaluate the safety and efficacy of tezacaftor monotherapy and of tezacaftor/ivacaftor combination therapy in subjects with cystic fibrosis homozygous for F508del or compound heterozygous for F508del and G551D. This was a randomized, placebo-controlled, double-blind, multicenter, phase 2 study (NCT01531673). Subjects homozygous for F508del received tezacaftor (10 to 150 mg) every day alone or in combination with ivacaftor (150 mg every 12 h) in a dose escalation phase, as well as in a dosage regimen testing phase. Subjects compound heterozygous for F508del and G551D, taking physician-prescribed ivacaftor, received tezacaftor (100 mg every day). Primary endpoints were safety through Day 56 and change in sweat chloride from baseline through Day 28. Secondary endpoints included change in percent predicted FEV 1 (ppFEV 1 ) from baseline through Day 28 and pharmacokinetics. The incidence of adverse events was similar across treatment arms. Tezacaftor (100 mg every day)/ivacaftor (150 mg every 12 h) resulted in a 6.04 mmol/L decrease in sweat chloride and 3.75 percentage point increase in ppFEV 1 in subjects homozygous for F508del, and a 7.02 mmol/L decrease in sweat chloride and 4.60 percentage point increase in ppFEV 1 in subjects compound heterozygous for F508del and G551D from baseline through Day 28 (P < 0.05 for all). These results support continued clinical development of tezacaftor (100 mg every day) in combination with ivacaftor (150 mg every 12 h) in subjects with cystic fibrosis. Clinical trial registered with www.clinicaltrials.gov (NCT01531673).

Kurt Gödels Brünner Verwandte

NASA Astrophysics Data System (ADS)

Müller, Dora

2007-11-01

The author of this memoir Dora Müller (born 1920) belongs - as well as Kurt Gödel-to the German minority playing an important role in the past life of Brno. The marriage of his son included her among the Gödels collaterals. She was chemist, but also pianist, historician, participant of antinacist movement and iniciator of Czech-German understanding after war. Following her personal experiences, remembrances of Gödels relatives and documental materials, she evokes the atmosphere of broader family milieu of Kurt Gödel.

44 CFR 295.2 - Policy.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Policy. 295.2 Section 295.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE General § 295.2 Policy. It is our policy to...

44 CFR 295.2 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Policy. 295.2 Section 295.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY CERRO GRANDE FIRE ASSISTANCE CERRO GRANDE FIRE ASSISTANCE General § 295.2 Policy. It is our policy to...

The novel c.247_249delTTC (p.F83del) GJB2 mutation in a family with prelingual sensorineural deafness.

PubMed

Petersen, Michael B; Grigoriadou, Maria; Koutroumpe, Maria; Kokotas, Haris

2012-07-01

Non-syndromic hearing loss is one of the most common hereditary determined diseases in human, and the disease is a genetically heterogeneous disorder. Mutations in the GJB2 gene, encoding connexin 26 (Cx26), are a major cause of non-syndromic recessive hearing impairment in many countries and are largely dependent on ethnic groups. Due to the high frequency of the c.35delG GJB2 mutation in the Greek population, we have previously suggested that Greek patients with sensorineural, non-syndromic deafness should be tested for the c.35delG mutation and the coding region of the GJB2 gene should be sequenced in c.35delG heterozygotes. Here we present on the clinical and molecular genetic evaluation of a family suffering from prelingual, sensorineural, non-syndromic deafness. A novel c.247_249delTTC (p.F83del) GJB2 mutation was detected in compound heterozygosity with the c.35delG GJB2 mutation in the proband and was later confirmed in the father, while the mother was homozygous for the c.35delG GJB2 mutation. We conclude that compound heterozygosity of the novel c.247_249delTTC (p.F83del) and the c.35delG mutations in the GJB2 gene was the cause of deafness in the proband and his father. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Estudio del CH interestelar

NASA Astrophysics Data System (ADS)

Olano, C.; Lemarchand, G.; Sanz, A. J.; Bava, J. A.

El objetivo principal de este proyecto consiste en el estudio de la distribución y abundancia del CH en nubes interestelares a través de la observación de las líneas hiperfinas del CH en 3,3 GHz. El CH es una molécula de amplia distribución en el espacio interestelar y una de las pocas especies que han sido observadas tanto con técnicas de radio como ópticas. Desde el punto de vista tecnológico se ha desarrollado un cabezal de receptor que permitirá la realización de observaciones polarimétricas en la frecuencia de 3,3 GHz, con una temperatura del sistema de 60 K y un ancho de banda de 140 MHz, y que será instalado en el foco primario de la antena parabólica del IAR. El cabezal del receptor es capaz de detectar señales polarizadas, separando las componentes de polarización circular derecha e izquierda. Para tal fin el cabezal consta de dos ramas receptoras que amplificarán la señal y la trasladarán a una frecuencia más baja (frecuencia intermedia), permitiendo de esa forma un mejor transporte de la señal a la sala de control para su posterior procesamiento. El receptor además de tener características polarimétricas, podrá ser usado en el continuo y en la línea, utilizando las ventajas observacionales y de procesamiento de señal que actualmente posee el IAR.

Características del viento en estrellas Be derivadas del perfil Hα

NASA Astrophysics Data System (ADS)

Rohrmann, R.; Cidale, L.

El estudio teórico de perfiles Hα y su variabilidad en estrellas Be ha sido frecuentemente desarrollado en base a modelos de envolturas circunestelares inhomogéneas, donde la geometría del material es responsable de la forma del perfil dependiendo de la dirección de observación. Nosotros damos una interpretación alternativa y proponemos que la mayoría de las propiedades de esta línea tienen origen en la base de un viento estelar y de una estructura cromosférica anexa a la fotósfera. Encontramos que típicos perfiles Hα en Be, como son los llamados pole-on y winebottle, pueden ser reproducidos cualitativamente sin recurrir a la existencia de una envoltura asimétrica. Analizamos como la línea Hα permite identificar la posible estructura del viento en la región donde éste se inicia.

Tierra del Fuego, Argentina, South America

NASA Technical Reports Server (NTRS)

1991-01-01

The Mitre Peninsula is the easternmost tip of Tierra del Fuego, Argentina, (54.5S, 65.5W). Early winter snow can be seen on this south tip of the Andes Mountains. These same mountains continue underwater to Antarctica. The Strait of Magellan, separating the South American mainland from Tierra del Fuego is off the scene to the north and west, but the Strait of LeMaire, separating Tierra del Fuego from the Isla de los Estados can be seen.

Unidades del paisaje de Puerto Rico: la influencia del clima, el substrato y la topografia

Treesearch

William Gould; Michael E. Jimenez; Gary Potts; Maya Quinones; Sebastian Martinuzzi

2008-01-01

El mapa de unidades del paisaje de Puerto Rico representa variaciones climaticas, topograficas y del substrato mediante la integracion de seis zonas climaticas (Ewel y Whitmore, 1973), seis substratos (Bawiec, 2001; USGS, 2005), cinco posiciones topograficas, o topoformas (Martinuzzi et al. 2007), y cuerpos de agua (USGS 2005). Los substratos representan el conjunto...

How Pore-Fluid Pressure due to Heavy Rainfall Influences Volcanic Eruptions, Example of 1998 and 2008 Eruptions of Cerro Azul (Galapagos)

NASA Astrophysics Data System (ADS)

Albino, F.; Amelung, F.; Gregg, P. M.

2016-12-01

About 30 worldwide seismic studies have shown a strong correlation between rainfall and earthquakes in the past 22 years (e.g. Costain and Bollinger, 2010). Such correlation has been explained by the phenomenon of hydro-seismicity via pore pressure diffusion: an increase of pore-fluid in the upper crust reduces the normal stress on faults, which can trigger shear failure. Although this pore pressure effect is widely known for earthquakes, this phenomenon and more broadly poro-elasticity process are not widely studied on volcanoes. However, we know from our previous works that tensile failures that open to propagate magma through the surface are also pore pressure dependent. We have demonstrated that an increase of pore pressure largely reduces the overpressure required to rupture the magma reservoir. We have shown that the pore pressure has more influence on reservoir stability than other parameters such as the reservoir depth or the edifice loading. Here, we investigate how small pore-fluid changes due to hydrothermal or aquifer refill during heavy rainfall may perturb the conditions of failure around magma reservoirs and, what is more, if these perturbations are enough to trigger magma intrusions. We quantify the pore pressure effect on magmatic system by combining 1) 1D pore pressure diffusion model to quantify how pore pressure changes from surface to depth after heavy rainfall events and 2) 2D poro-elastic numerical model to provide the evolution of failure conditions of the reservoir as a consequence of these pore pressure changes. Sensitivity analysis is also performed to characterize the influence on our results of the poro-elastic parameters (hydraulic diffusivity, permeability and porosity) and the geometry of the magma reservoir and the aquifer (depth, size, shape). Finally, we apply our methodology to Cerro Azul volcano (Galapagos) where both last eruptions (1998 and 2008) occurred just after heavy rainfall events, without any pre-eruptive inflation. In

A New Tradition To Fit the Model.

ERIC Educational Resources Information Center

Darnell, D. Roe; Rosenthal, Donna McCrohan

2001-01-01

Discusses Cerro Coso Community College in Ridgecrest (California), where 80-85 of all local jobs are with one employer, the China Lake Naval Air Weapons Station (NAWS). States that massive layoffs at NAWS inspired creative ways of rethinking the community college model at Cerro Coso, such as creating the nation's first computer graphics imagery…

Analisis del contenido curricular de los Documentos Normativos del Programa de Ciencias en el area de biologia para la escuela superior del sistema de educacion publica de Puerto Rico: 1993-2012

NASA Astrophysics Data System (ADS)

Davila Montanez, Melissa

Esta investigacion de naturaleza cualitativa se ocupo de realizar un analisis de contenido documental de los Documentos Normativos del Programa de Ciencias en el area de biologia de la escuela superior del sistema de educacion publica de Puerto Rico del periodo 1993-2012. Los documentos analizados fueron: Guia Curricular, 1995; Marco Curricular, 2003; Estandares de Excelencia, 1996, 2000 y Estandares de Contenido y Expectativas de Grado, 2007. Se indago si hubo cambios en significados en los Componentes Estructurales: Naturaleza de la ciencia, Paradigmas para la ensenanza de la ciencia, Funcion del curriculo formal, Mision de la ensenanza de la ciencia; Contenidos, destrezas y competencias, Estrategias de ensenanza y Evaluacion/Assessment del aprendizaje. El analisis sugiere que no hubo cambios sustanciales en los significados de los Componentes Estructurales. Los documentos estudiados muestran mayormente caracteristicas similares, aunque los documentos mas recientes eran mas descriptivos, explicativos y especificos.

Estudio teórico del CO2. Orbitales de valencia y del ``core''

NASA Astrophysics Data System (ADS)

Olalla Gutiérrez, E.

Hemos calculado las intensidades de las transiciones E1 a los miembros de las series de Rydberg con origen en los orbitales ``no enlazantes'' del dióxido de carbono, especie de conocida relevancia atmosférica. Se han computado, asimismo, los continuos de fotoionización correspondientes a los distintos canales de ionización, representándolos como densidad espectral de fuerza de oscilador frente a la energía del fotón incidente; mostramos los resultados df/dE para la fotoionización total de esta especie en el intervalo 15-60 eV. Todos los cálculos se han llevado a cabo mediante la formulación Molecular del Método de los Orbitales de Defecto Cuántico, MQDO [1,2]. La calidad de los resultados que presentamos se ha evaluado en base a la comparación con los datos, tanto experimentales como teóricos, disponibles en la bibliografía. El acuerdo encontrado es altamente satisfactorio

Visiting the Gödel universe.

PubMed

Grave, Frank; Buser, Michael

2008-01-01

Visualization of general relativity illustrates aspects of Einstein's insights into the curved nature of space and time to the expert as well as the layperson. One of the most interesting models which came up with Einstein's theory was developed by Kurt Gödel in 1949. The Gödel universe is a valid solution of Einstein's field equations, making it a possible physical description of our universe. It offers remarkable features like the existence of an optical horizon beyond which time travel is possible. Although we know that our universe is not a Gödel universe, it is interesting to visualize physical aspects of a world model resulting from a theory which is highly confirmed in scientific history. Standard techniques to adopt an egocentric point of view in a relativistic world model have shortcomings with respect to the time needed to render an image as well as difficulties in applying a direct illumination model. In this paper we want to face both issues to reduce the gap between common visualization standards and relativistic visualization. We will introduce two techniques to speed up recalculation of images by means of preprocessing and lookup tables and to increase image quality through a special optimization applicable to the Gödel universe. The first technique allows the physicist to understand the different effects of general relativity faster and better by generating images from existing datasets interactively. By using the intrinsic symmetries of Gödel's spacetime which are expressed by the Killing vector field, we are able to reduce the necessary calculations to simple cases using the second technique. This even makes it feasible to account for a direct illumination model during the rendering process. Although the presented methods are applied to Gödel's universe, they can also be extended to other manifolds, for example light propagation in moving dielectric media. Therefore, other areas of research can benefit from these generic improvements.

Extensión del Formalismo de Orbitales de Defecto Cuántico al tratamiento del efecto Stark (SQDO).

NASA Astrophysics Data System (ADS)

Menéndez, J. M.; Martín, I.; Velasco, A. M.

El estudio experimental de las interacciones de átomos Rydberg altamente excitados con campos eléctricos ha experimentado un creciente interés durante las dos últimas décadas debido, en gran medida, al desarrollo de nuevas técnicas para crear y estudiar átomos Rydberg en el laboratorio. Acompañando a estas nuevas técnicas experimentales, es necesario el desarrollo de modelos teóricos que nos permitan contrastar sus medidas y conocer mejor los fundamentos de los mismos. Desde el punto de vista teórico el conocimiento del desdoblamiento de los niveles energéticos de un átomo en función de la magnitud del campo eléctrico aplicado (lo que se conoce como mapa Stark) es el mejor punto de partida para la descripción del sistema y un prerrequisito fundamental para el cálculo de distintas propiedades atómicas en presencia del campo eléctrico tales como intensidades de transición, umbrales de ionización de campo eléctrico, tiempos de vida, posición y anchura de cruces evitados, etc. En este trabajo presentamos la adaptación del método de orbitales de defecto cuántico [1,2,3] al tratamiento del efecto Stark (SQDO) [4] y su aplicación al cálculo de los desdoblamientos energéticos y fuerzas de oscilador de estados Rydberg en los átomos de Li, Na y K. El propósito de este estudio es, por un lado, desarrollar métodos fiables para la determinación de propiedades atómicas en presencia de campos eléctricos y, por otro, mostrar la fiabilidad de las funciones de onda QDO en la descripción del efecto Stark en sistemas atómicos.

Gödel universes in string theory

NASA Astrophysics Data System (ADS)

Barrow, John D.; Dabrowski, Mariusz P.

1998-11-01

We show that homogeneous Gödel spacetimes need not contain closed timelike curves in low-energy-effective string theories. We find exact solutions for the Gödel metric in string theory for the full O(α') action including both dilaton and axion fields. The results are valid for bosonic, heterotic and super-strings. To first order in the inverse string tension α', these solutions display a simple relation between the angular velocity of the Gödel universe, Ω, and the inverse string tension of the form α'=1/Ω2 in the absence of the axion field. The generalization of this relationship is also found when the axion field is present.

Predicting Change in Sediment Transport Rates in the Wake of the Cerro Grande Fire: Limitations and Potential of a Physically-based Approach

NASA Astrophysics Data System (ADS)

Canfield, H. E.; Wilson, C. J.; Lane, L. J.; McLin, S. G.; Earles, A.

2001-12-01

One of the benefits of physically based hydrologic models is that since they are based on physics, they can potentially be used to describe hydrologic response to change. On the Pajarito Plateau in New Mexico the introduction of cattle in the late 1800s, and then establishment of the Los Alamos National Laboratory in the 1940s has had a profound effect on the cover on the watersheds surrounding Los Alamos, with a proliferation of a more dense under story, on the hillsides, and more impermeable areas at the town site. Since the establishment of the Laboratory, there have been several large forest fires, most recently, the Cerro Grande Fire in May 2000. Hydrologic models suggest an eight-fold increase in the 100yr-6hr-flood peak in Los Alamos Canyon, and a corresponding three to four fold increase in sediment transport in the Canyon under post-burn conditions. However, the magnitude of the predicted scour depends strongly on what processes are allowed to occur in the model. The predicted scour is much greater if the model incorporates an observed inset channel, where modeled velocities are much greater than in the full wetted area. Furthermore, the model suggests that armoring has the potential to cut off the supply of sediment in the bed, so that scour and sediment transport are limited by the capability of the flow to transport larger particles that might otherwise armor the bed. Therefore, the magnitude of the predicted increase in sediment transport depends strongly on the ability of channels to armor as well as an a-priori understanding of how scour and deposition will occur in the canyon in response to flows much greater than the historical record. As such, reliance on model estimates of sediment transport based on the physics of flow is inadequate for assessing the effects of change and, at-best, provides only a range in the possible response to an extreme event. In this poster we examine available data on post-fire armoring rates, and observations about

PIA Program | CTIO

Science.gov Websites

se cuenta con los fondos necesarios para efectuar el Programa PIA para el 2018. We do, on occasion Observatorio Inter-Americano de Cerro Tololo es el centro nacional de los Estados Unidos para el desarrollo de unos 400 kms al norte de Santiago. Los telescopios se ubican en la cima de Cerro Tololo, a 90 kms al

Calc-silicate mineralization in active geothermal systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bird, D.K.; Schiffman, P.; Elders, W.A.

The detailed study of calc-silicate mineral zones and coexisting phase relations in the Cerro Prieto geothermal system were used as examples for thermodynamic evaluation of phase relations among minerals of variable composition and to calculate the chemical characteristics of hydrothermal solutions compatible with the observed calc-silicate assemblages. In general there is a close correlation between calculated and observed fluid compositions. Calculated fugacities of O{sub 2} at about 320{degrees}C in the Cerro Prieto geothermal system are about five orders of magnitude less than that at the nearby Salton Sea geothermal system. This observation is consistent with the occurrence of Fe{sup 3+}more » rich epidotes in the latter system and the presence of prehnite at Cerro Prieto.« less

Calidad de Imagen del Telescopio UNAM212

NASA Astrophysics Data System (ADS)

Cobos, F. J.; Teiada de Vargas, C.

1987-05-01

El telescopio UNAM2l2, del Observatorio Astronómico Nacional, situado en la Sierra de San Pedro Mártir (Baja California, México), cumplira en un futuro muy cercano siete años de uso para fines de investigación astronómica. Aunque en este tiempo no se ha efectuado un estudio sistemático acerca de su comportamiento óptico y de los factores que influyen en la calidad de las imágenes, se han realizado pruebas diversas, estudios parciales y reuniones especificas, cuyos resultados no siempre se han difundido ampliamente y generalmente no se han presentado por escrito. Es por ello que hemos creido necesario intentar una recopilación de la información existente para poder con ella establecer un diagnóstjco que, aunque no sea definitivo, sirva de base para futuros trabajos tendientes a optimizar el comportamiento óptico del telescopio. Es evidente que un buen número de las conclusiones que se presentan son resultado del trabajo de muchas personas ó de esfuerzos colectivos. Asimismo, hemos tratado de localizar información bibliográfica que pueda ser de utilidad. Nuestro objetivo primordial ha consistido en centrarnos en la óptica del telescopio y su calidad, pero también se han considerado otros aspectos que puedan afectar las imágenes obtenidas tales como: celda del primario, `seeing' local y externo, flexiones posibles en la estructura mecánica del telescopio, etc.

Conservacion de truchas del Pacifico

Treesearch

Brooke E. Penaluna

2016-01-01

La historia de las truchas del Pacífico, pertenecientes al género Oncorhynchus, es una historia muy interesante que se basa en la persistencia y diversificación de sus especies debido, en gran parte, al dinamismo propio que existe en su medio ambiente. Desde el oeste de Norteamérica, extendiéndose hasta el este de Asia, las truchas del Pacífico han experimentado la...

Site Protection Efforts at the AURA Observatory in Chile

NASA Astrophysics Data System (ADS)

Smith, R. Chris; Smith, Malcolm G.; Sanhueza, Pedro

2015-08-01

The AURA Observatory (AURA-O) was the first of the major international observatories to be established in northern Chile to exploit the optimal astronomical conditions available there. The site was originally established in 1962 to host the Cerro Tololo Inter-American Observatory (CTIO). It now hosts more than 20 operational telescopes, including some of the leading U.S. and international astronomical facilities in the southern hemisphere, such as the Blanco 4m telescope on Cerro Tololo and the Gemini-South and SOAR telescopes on Cerro Pachón. Construction of the next generation facility, the Large Synoptic Survey Telescope (LSST), has recently begun on Cerro Pachón, while additional smaller telescopes continue to be added to the complement on Cerro Tololo.While the site has become a major platform for international astronomical facilities over the last 50 years, development in the region has led to an ever-increasing threat of light pollution around the site. AURA-O has worked closely with local, regional, and national authorities and institutions (in particular with the Chilean Ministries of Environment and Foreign Relations) in an effort to protect the site so that future generations of telescopes, as well as future generations of Chileans, can benefit from the dark skies in the region. We will summarize our efforts over the past 15 years to highlight the importance of dark sky protection through education and public outreach as well as through more recent promotion of IDA certifications in the region and support for the World Heritage initiatives described by others in this conference.

Estudio fotométrico de estrellas tardías de alta luminosidad en 23 cúmulos abiertos

NASA Astrophysics Data System (ADS)

Clariá, J. J.; Piatti, A. E.; Osborn, W.

Se presentan resultados obtenidos en los Observatorios de Cerro Tololo, Kitt Peak, Lowell y Las Campanas, a partir de fotometría UBV y DDO de 54 estrellas tardías de alta luminosidad en 23 cúmulos abiertos. La aplicación de dos criterios fotométricos independientes permite asignar a cada estrella probabilidades de pertenencia a cada agregado. Se encuentra que 32 estrellas son muy probablemente miembros de los cúmulos, mientras que las restantes son objetos del campo. En todos los casos se determinan excesos de color E(B-V) a través de procedimientos fotométricos y espectroscópicos tradicionales. Recientes calibraciones del sistema DDO permiten, además, derivar tipos espectrales MK, temperaturas efectivas, y abundancias superficiales de la muestra examinada. Las metalicidades DDO derivadas se distribuyen entre valores típicos de cúmulos moderadamente pobres en metales ([Fe/H]~=-0.3) y moderadamente ricos ([Fe/H]~=0.2), en tanto que las masas calculadas para las gigantes rojas oscilan entre 1 y 4 masas solares, con una dispersión dentro de cada cúmulo menor que 1 Msolar.

Morphology, geology and geochemistry of the "Salar del Gran Bajo del Gualicho" (Rio Negro, Argentina)

USGS Publications Warehouse

Angelucci, A.; Barbieri, M.; Brodtkorb, A.; Ciccacci, S.; Civitelli, G.; De Barrio, R.; Di, Filippo M.; Fredi, P.; Friedman, I.; Lombardi, S.; Schalamuk, A.I.; Toro, B.

1996-01-01

A multidisciplinary study of the Gran Bajo del Gualicho area (Rio Negro - Argentina) was carried out; the aim was to delineate its geological and geomorphological evolution and to estabilish the genesis of salts filling the depression. Climatic conditions were analized first to individuate their role in the present morphogenetic processes; moreover the main morphological features of present landscape were examined as well as the stratigraphy of the outcropping formations, and of the Gran Bajo del Gualicho Formation in particular. Finally, a possible geomorphological evolution of the studied area was traced. Geophysical analyses allowed to estabilish that the paleosurface shaped on the crystalline basement is strongly uneven and shows evidence of the strong tectonic phases it underwent. The result of isotope analyses confirmed that the salt deposits on the Gran Bajo del Gualicho bottom were produced by fresh water evaporation, while strontium isotope ratio suggested that such waters were responsible for solubilization of more ancient evaporitic deposits.

Nevado del Huila, Columbia

NASA Technical Reports Server (NTRS)

2007-01-01

Nevado del Huila Volcano in Colombia is actually a volcanic chain running north to south, capped by a glacier. With peaks ranging in height from 2,600 to 5,780 meters (8,530 to 18,960 feet), Nevado del Huila is a stratovolcano composed of alternating layers of hardened lava, solidified ash, and volcanic rocks. Its first recorded eruption occurred in the mid-sixteenth century. The long-dormant volcano erupted again in mid-April 2007. A few months before the eruption, the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite captured this image of Nevado del Huila, on February 23, 2007. In this image, the bright white area just east of the central summit is ice. Immediately west of the summit are bare rocks, appearing as blue-gray. West of those rocks, white reappears, but this patch of white results from clouds hovering in the nearby valley. In the east, the colors turn to brown (indicating bare rock) and bright green (indicating vegetation). ASTER photographed Nevado del Huila near the end of a long phase of quietude. On April 17, 2007, local authorities recorded seismic activity associated with rock fracturing on the volcano's central summit, according to the ReliefWeb Website. Activity intensified the following day with an eruption and mudflows, forcing thousands of nearby residents to evacuate. As the Associated Press reported, the eruption caused avalanches and floods that wiped away both houses and bridges. It marked the volcano's first recorded eruption since the Spanish colonized the area five centuries earlier. NASA image created by Jesse Allen, using data provided courtesy of the NASA/GSFC/MITI/ERSDAC/JAROS, and U.S./Japan ASTER Science Team.

Calidad del aire interior en las escuelas

EPA Pesticide Factsheets

EPA ha desarrollado el Programa de Herramientas de Calidad del Aire Interior para las Escuelas para reducir la exposición a los contaminantes ambientales en las mismas a través de la adopción voluntaria de las prácticas para manejar la calidad del aire int

El Morro caldera (33° 10‧ S, 66° 24‧ W), San Luis, Argentina: An exceptional case of fossil pre-collapse updoming

NASA Astrophysics Data System (ADS)

Sruoga, P.; Ibañes, O. D.; Japas, M. S.; Urbina, N. E.

2017-05-01

Volcanism at Sierra del Morro represents the final stages of the flat-slab related magmatism in the easternmost San Luis Neogene Volcanic Belt. This 80 km-long NW-WNW-trending belt tracks the episodic inland migration of both magmatism and tectonic deformation since 18 Ma. The Sierra del Morro stands out in the Eastern Sierras Pampeanas as a metamorphic block uplifted during the Late Miocene-Pleistocene by a combination of magma injection and tectonic deformation. Although sequences that preserve stages of basement updoming are not often preserved, exposures in Sierra del Morro are exception in providing key evidence and insight into the involved processes. Based on the comprehensive study of volcanic stratigraphy and structures, the reconstruction of the volcanic architecture has been carried out. We infer a three stage evolution of the El Morro caldera as follows: 1) pre-collapse updoming and volcanism, 2) collapse caldera formation and 3) post-caldera volcanism. The ascent of magma is recorded in small tumescence sites, strongly controlled by oblique transtensional WNW-NW and ENE-striking brittle-ductile megashear zones. Even though the area affected by tumescence was large, magma injection progressed only locally. At Cerros Guanaco and Pampa, metamorphic rocks were updomed and strongly brecciated, whereas at Sierra del Morro magma was emplaced as pre-collapse domes with associated block-and-ash flows, ignimbrite caldera-forming eruptions and post-caldera lava domes and dykes. The caldera is located in the intersection of two major oblique transtensional WNW-NW and ENE-trending brittle-ductile megashear zones, where the highest positive dilatation occurred.

Performance Assessment of Flashed Steam Geothermal Power Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alt, Theodore E.

1980-12-01

Five years of operating experience at the Comision Federal de Electricidad (CFE) Cerro Prieto flashed steam geothermal power plant are evaluated from the perspective of U. S. utility operations. We focus on the design and maintenance of the power plant that led to the achievement of high plant capacity factors for Units No. 1 and 2 since commercial operation began in 1973. For this study, plant capacity factor is the ratio of the average load on the machines or equipment for the period of time considered to the capacity rating of the machines or equipment. The plant capacity factor ismore » the annual gross output in GWh compared to 657 GWh (2 x 37.5 MW x 8760 h). The CFE operates Cerro Prieto at base load consistent with the system connected electrical demand of the Baja California Division. The plant output was curtailed during the winter months of 1973-1975 when the system electric demand was less than the combined output capability of Cerro Prieto and the fossil fuel plant near Tijuana. Each year the system electric demand has increased and the Cerro Prieto units now operate at full load all the time. The CFE added Units 3 and 4 to Cerro Prieto in 1979 which increased the plant name plate capacity to 150 MW. Part of this additional capacity will supply power to San Diego Gas and Electric Company through an interconnection across the border. The achievement of a high capacity factor over an extensive operating period was influenced by operation, design, and maintenance of the geothermal flash steam power plant.« less

May Gödel's Ideas Be Addressed Philosophically?

NASA Astrophysics Data System (ADS)

Dokulil, Miloš

2007-11-01

Gödel emphasised philosophy as an important tool in science. Much less is known about his religious background. We should bear in mind that our evaluational perspective differs very much from the one in which Gödel lived. He was personally sure that there must be another existence after death-an afterlife (''of unlimited life span''). As a ''Baptized Lutheran'' he did not include ''Trinity'' in his creed. He was also certain that mind is separate from matter. This text tries to include Libet's ''readiness potential'' into the debate concerning the specificity of the mind. Neither Gödel's identification of materialism with mechanism nor his vision of the ''spirit'' are a viable solution of the problem.

Crystallization conditions and petrogenesis of the lava dome from the ˜900 years BP eruption of Cerro Machín Volcano, Colombia

NASA Astrophysics Data System (ADS)

Laeger, Kathrin; Halama, Ralf; Hansteen, Thor; Savov, Ivan P.; Murcia, Hugo F.; Cortés, Gloria P.; Garbe-Schönberg, Dieter

2013-12-01

The last known eruption at Cerro Machín Volcano (CMV) in the Central Cordillera of Colombia occurred ˜900 years BP and ended with the formation of a dacitic lava dome. The dome rocks contain both normally and reversely zoned plagioclase (An24-54), unzoned and reversely zoned amphiboles of dominantly tschermakite and pargasite/magnesio-hastingsite composition and olivine xenocrysts (Fo = 85-88) with amphibole/clinopyroxene overgrowth, all suggesting interaction with mafic magma at depth. Plagioclase additionally exhibits complex oscillatory zoning patterns reflecting repeated replenishment, fractionation and changes in intrinsic conditions in the magma reservoir. Unzoned amphiboles and cores of the reversely zoned amphiboles give identical crystallization conditions of 910 ± 30 °C and 360 ± 70 MPa, corresponding to a depth of about 13 ± 2 km, at moderately oxidized conditions (f = +0.5 ± 0.2 ΔNNO). The water content in the melt, calculated based on amphibole chemistry, is 7.1 ± 0.4 wt.%. Rims of the reversely zoned amphiboles are relatively enriched in MgO and yield higher crystallization temperatures (T = 970 ± 25 °C), slightly lower melt H2O contents (6.1 ± 0.7 wt.%) and overlapping pressures (410 ± 100 MPa). We suggest that these rims crystallized following an influx of mafic melt into a resident magma reservoir at mid-crustal depths, further supported by the occurrence of xenocrystic olivine. Crystallization of biotite, albite-rich plagioclase and quartz occurred at comparatively low temperatures (probably <800 °C) during early stages of ascent or storage at shallower levels. Based on amphibole mineral chemistry, the felsic resident melt had a rhyolitic composition (71 ± 2 wt.% SiO2), whereas the hybrid magma, from which the amphibole rims crystallized, was dacitic (64 ± 3 wt.% SiO2). The bulk rock chemistry of the CMV lava dome dacites is homogenous. They have elevated (La/Nb)N ratios of 3.8-4.5, typical for convergent margin magmas, and display

Efecto del Programa de Entrenamiento “Manejo del Dolor” en la Documentación de Enfermería en el Expediente Electrónico

PubMed Central

Monsiváis, María Guadalupe Moreno; Guzmán, Ma. Guadalupe Interial; Flores, Paz Francisco Sauceda; Arreola, Leticia Vázquez

2012-01-01

Resumen En el presente trabajo se muestra la importancia de entrenar al personal de enfermería para mejorar la documentación en el expediente electrónico. Se eligió el manejo del dolor por ser un área prioritaria; una alta proporción de pacientes en período post operatorio cursa con dolor, por lo tanto, la documentación debe ser útil para la toma de decisiones clínicas. Se implementó un programa de entrenamiento denominado “Manejo del Dolor” dirigido al personal de enfermería. Se utilizó la tecnología de la información como herramienta para fortalecer el conocimiento con base en la revisión sistemática de la literatura; el personal de enfermería participante seleccionó la mejor evidencia; posteriormente se trabajó en la transferencia de este conocimiento a la práctica a través del diseño de un protocolo para el manejo del dolor. Se concluye que el conocimiento del manejo del dolor es fundamental para que enfermería documente con mayor precisión sus intervenciones. PMID:24199106

Operation and Performance of a Biphase Turbine Power Plant at the Cerro Prieto Geothermal Field (Final Report)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hays, Lance G.

2000-09-01

A full scale, wellhead Biphase turbine was manufactured and installed with the balance of plant at Well 103 of the Cerro Prieto geothermal resource in Baja, California. The Biphase turbine was first synchronized with the electrical grid of Comision Federal de Electricidad on August 20, 1997. The Biphase power plant was operated from that time until May 23, 2000, a period of 2 years and 9 months. A total of 77,549 kWh were delivered to the grid. The power plant was subsequently placed in a standby condition pending replacement of the rotor with a newly designed, higher power rotor andmore » replacement of the bearings and seals. The maximum measured power output of the Biphase turbine, 808 kWe at 640 psig wellhead pressure, agreed closely with the predicted output, 840 kWe. When combined with the backpressure steam turbine the total output power from that flow would be increased by 40% above the power derived only from the flow by the present flash steam plant. The design relations used to predict performance and design the turbine were verified by these tests. The performance and durability of the Biphase turbine support the conclusion of the Economics and Application Report previously published, (Appendix A). The newly designed rotor (the Dual Pressure Rotor) was analyzed for the above power condition. The Dual Pressure Rotor would increase the power output to 2064 kWe by incorporating two pressure letdown stages in the Biphase rotor, eliminating the requirement for a backpressure steam turbine. The power plant availability was low due to deposition of solids from the well on the Biphase rotor and balance of plant problems. A great deal of plant down time resulted from the requirement to develop methods to handle the solids and from testing the apparatus in the Biphase turbine. Finally an online, washing method using the high pressure two-phase flow was developed which completely eliminated the solids problem. The availability of the Biphase turbine itself was

Hydrogeologic investigations of the southern Española Basin, NM

NASA Astrophysics Data System (ADS)

Earney, T.; Christensen, D.; Horton, A.; Folsom, M.; Kelley, S.

2017-12-01

For the past 5 years, students participating in the Summer of Applied Geophysical Experience (SAGE) have been studying groundwater conditions in the southern Española Basin, in northern New Mexico, with a goal of developing a better understanding of both regional and local scale geothermal anomalies. A regional geothermal gradient map constructed over the study area indicates that there are two regions with anomalously high geothermal gradients, one associated with the Buckman municipal wellfield (BMWF) and the other in the vicinity of the Cerros del Rio volcanic field. Overproduction at the BMWF was responsible for a 100 meter drop in groundwater levels between 1989 and 2003, leading to a significant amount of land subsidence. Repeat measurements of thermal profiles for several monitoring wells at Buckman reveal incremental warming over a 5 year period from 2013 to 2017. Additionally, land elevation recovery was documented between 2007 and 2010 using InSAR (Interferometric Synthetic Aperture Radar). These observations are inferred to be a response to decreased production rates in nearby wells Buckman 1 and 8. This suggests that the groundwater flow system at Buckman is still in a state of recovery from the years of overproduction. The proximity of the well field to a small mapped fault near Buckman 8 potentially explains why geothermal gradients are anomalously high at the BMWF. Monitoring well SF-2b received special attention in an attempt to explain a localized thermal anomaly between 200 and 230 meters down hole. Explanations including geology (faults and stratigraphy) and interference from nearby production wells do not seem to account for the anomaly. The anomaly is therefore interpreted as the result of a damaged casing. Elevated geothermal anomalies at the Cerros del Rio volcanic field could be explained by structural and textural changes to groundwater flow units that occurred when aligned plug and dikes feeding volcanic vents intruded along faults. A

High Pressure Dehydration of Antigorite in Nature: Embrittlement and melt formation?

NASA Astrophysics Data System (ADS)

Evans, B. W.; Cowan, D. S.

2011-12-01

Trommsdorff and others in 1998 provided field evidence from the Cerro del Almirez ultramafic complex, S. Spain, for the only known example of the high-pressure terminal breakdown reaction of antigorite: Atg = Ol + Opx + Chl + H2O. Pressure-temperature conditions for this reaction have since been refined to around 1.8 GPa and 650-700C. Associated mafic rocks are eclogites. Reaction products were a mixture of more-or-less granoblastic chlorite meta-harzburgite and rock of the same composition with a spinifex-like texture comprising up to 10 cm long needles of olivine and interstitial bundles of enstatite prisms. This texture was interpreted as metamorphic in origin (jackstraw olivine), and this view has apparently generally been accepted. Two earlier studies interpreted the spinifex-like rocks as quenched ultramafic liquid, analogous to komatiites. Given the release of ca. 6-7 wt.% H2O by this reaction, one must surely contemplate the possibility of dehydration embrittlement and frictional slip in shear zones, as many have suggested for antigorite breakdown in subduction zones. The depth and location of earthquake hypocenters have been shown to correlate well with the P-T trace of the experimentally determined antigorite breakdown reaction. A temperature rise of only 300C is needed at 1.8 GPa to initiate partial melting of hydrous peridotite, and another 350C to render it fully molten. These kinds of increase in temperature have been described from pseudotachylytes. We are therefore inclined to interpret the spinifex rocks at Cerro del Almirez as products of quench crystallization of ultramafic pseudotachylyte melt. This view is supported by the curved, branching, and sub-parallel nature of some of the olivine needles. Curved needles (up to 30 degrees) are not a feature of metamorphic jackstraw olivine, although otherwise the textures are very similar. Our view is also supported by the high contents of Cr and Ti (now exsolved into chromite and ilmenite) in the

33 CFR 110.65 - Indian River Bay, Del.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Indian River Bay, Del. 110.65 Section 110.65 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing...

El Atlas del Bosque Nacional El Yunque

Treesearch

Maya Quiñones; Isabel K. Parés-Ramos; William A. Gould; Grizelle Gonzalez; Kathleen McGinley; Pedro. Ríos

2018-01-01

Esta publicación es un esfuerzo colaborativo entre el Instituto Internacional de Dasonomía Tropical y el Bosque Nacional El Yunque para proveer mapas y análisis de información espacial actualizados sobre una importante reserva natural en Puerto Rico y el único bosque tropical dentro del Sistema de Bosques Nacionales de los Estados Unidos. El Atlas del Bosque Nacional...

Composición química de cúmulos globulares galácticos: metalicidades derivadas a partir de fotometría de Washington

NASA Astrophysics Data System (ADS)

Torres, M. C.; Clariá, J. J.

Se presentan temperaturas efectivas y abundancias de 183 gigantes rojas en 7 cúmulos globulares galácticos, derivadas a partir de fotometría de Washington realizada en Cerro Tololo. Las metalicidades provienen de una calibración que tiene en cuenta la disminución de sensibilidad de algunos índices con la temperatura. Los valores medios de [Fe/H] obtenidos oscilan entre -1.2 y -2.15, con errores típicos del orden de 0.2 salvo un par de excepciones. Teniendo en cuenta que el índice (C-T1) es significativamente más sensible a la metalicidad que (V-I), se presenta una calibración de abundancia basada en el color (C-T1)o de la rama gigante roja para una determinada magnitud absoluta M(T1). Las abundancias derivadas confirman en general la escala de Zinn (1985, ApJ, 293, 424).

33 CFR 110.65 - Indian River Bay, Del.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence 354...

33 CFR 110.65 - Indian River Bay, Del.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence 354...

33 CFR 110.65 - Indian River Bay, Del.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence 354...

33 CFR 110.65 - Indian River Bay, Del.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Indian River Bay, Del. 110.65... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.65 Indian River Bay, Del. Beginning at a point bearing... State highway bridge across Indian River Inlet; thence 174°, 600 feet; thence 264°, 800 feet; thence 354...

Trio of Stellar Occultations by Pluto One Year Prior to New Horizons’ Arrival

DTIC Science & Technology

2016-04-02

7 Department of Astronomy , Williams College, 33 Lab Campus Drive, Williamstown, MA 01267-2565, USA; chs2@williams.edu, bbabcock@williams.edu 8 Cerro...for Research in Astronomy (SARA), the MPI/ESO 2.2 m on La Silla, and the 0.45 m Cerro Calán telescope and 0.36 telescope in Constitución in Chile on...10 Also MIT, Cambridge, MA, USA. 11 Also Keck Northeast Astronomy Consortium Summer Fellow at Williams College, from Middlebury College, Middlebury, VT

VizieR Online Data Catalog: Young stellar objects in NGC 6823 (Riaz+, 2012)

NASA Astrophysics Data System (ADS)

Riaz, B.; Martin, E. L.; Tata, R.; Monin, J.-L.; Phan-Bao, N.; Bouy, H.

2016-10-01

The optical V-, R- and I-band images were obtained using the Prime Focus camera [William Herschel Telescope (WHT)/Wide Field Camera (WFC) detector] mounted on 4-m WHT in La Palma, Canary Islands, Spain. Observations were performed in 2005 May, The NIR J-, H-, Ks-band images were obtained using the Infrared Side Port Imager (ISPI) mounted on Cerro Tololo Inter-American Observatory (CTIO) 4-m Blanco Telescope in Cerro Tololo, Chile. Observations were performed in 2007 March. (3 data files).

Del-1 Expression as a Potential Biomarker in Triple-Negative Early Breast Cancer.

PubMed

Lee, Soo Jung; Lee, Jeeyeon; Kim, Wan Wook; Jung, Jin Hyang; Park, Ho Yong; Park, Ji-Young; Chae, Yee Soo

2018-01-01

A differential diagnostic role for plasma Del-1 was proposed for early breast cancer (EBC) in our previous study. We examined tumoral Del-1 expression and analyzed its prognostic impact among patients with EBC. Del-1 mRNA expression was assessed in breast epithelial and cancer cells. Meanwhile, the tumoral expression of Del-1 was determined based on tissue microarrays and immunohistochemistry results from 440 patients. While a high Del-1 mRNA expression was found in all the breast cancer cell lines, the expression was significantly higher in MDA-MB-231. Tumoral expression of Del-1 was also significantly associated with a negative expression of estrogen receptor or progesterone receptor, and low expression of Ki-67, particularly in the case of triple-negative breast cancer (TNBC) (p < 0.036). Furthermore, a correlation was found between Del-1 expression and an aggressive histological grade, nuclear mitosis, and polymorphism, suggesting a possible role in tumor progression. In the survival analysis, a worse distant disease-free survival trend was noted for the group overexpressing Del-1. While all the investigated breast cancer cell lines exhibited Del-1 expression, the expression rate and intensity were specifically prominent in TNBC. In addition, based on its relationship to an unfavorable histology and worse survival trend, Del-1 could act as a molecular target in TNBC patients. © 2018 S. Karger AG, Basel.

Forensic applicability of multi-allelic InDels with mononucleotide homopolymer structures.

PubMed

Zhang, Shu; Zhu, Qiang; Chen, Xiaogang; Zhao, Yuancun; Zhao, Xiaohong; Yang, Yiwen; Gao, Zehua; Fang, Ting; Wang, Yufang; Zhang, Ji

2018-04-27

Insertion/deletion polymorphisms (InDels), which possess the characteristics of low mutation rates and a short amplicon size, have been regarded as promising markers for forensic DNA analysis. InDels can be classified as bi-allelic or multi-allelic, depending on the number of alleles. Many studies have explored the use of bi-allelic InDels in forensic applications, such as individual identification and ancestry inference. However, multi-allelic InDels have received relatively little attention. In this study, InDels with 2-6 alleles and a minor allele frequency ≥0.01, in Chinese Southern Han (CHS), were retrieved from the 1000 Genomes Project Phase III. Based on the structural analysis of all retrieved InDels, 17 multi-allelic markers with mononucleotide homopolymer structures were selected and combined in one multiplex PCR reaction system. Sensitivity, species specificity and applicability in forensic case work of the multiplex were analyzed. A total of 218 unrelated individuals from a Chinese Han population were genotyped. The combined discriminatory power (CDP), the combined match probability (CMP) and the cumulative probability of exclusion (CPE) were 0.9999999999609, 3.91E-13 and 0.9956, respectively. The results demonstrated that this InDel multiplex panel was highly informative in the investigated population and most of the 26 populations of the 1000 Genomes Project. The data also suggested that multi-allelic InDel markers with monomeric base pair expansions are useful for forensic applications. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Main natural hazards and vulnerability studies for some historical constructions and urban sectors of Valparaiso City (Chile)

NASA Astrophysics Data System (ADS)

Romanelli, F.

2009-04-01

The Project "MAR VASTO" ("Risk Management in Valparaíso/Manejo de Riesgos en Valparaíso, Servicios Técnicos", 2007) started in March 2007, with coordination of ENEA (Italian Agency for New Technologies, Energy and Environment), participation of several partners (Italy: University of Ferrara, Faculties of Architecture and Engineering; University of Padua, Faculty of Engineering; Abdus Salam International Centre for Theoretical Physics of Trieste; Chile: Valparaíso Technical University Federico Santa Maria, Civil Works Department; Santiago University of Chile, Division Structures Constructions Geotechnics), and support of local stakeholders. Being Valparaíso included since 2003 in the UNESCO Word Heritage List of protected sites, the project main goals are the following: to collect, analyze and elaborate the existing information, with a satisfying evaluation of main hazards; to develop a GIS digital archive, well organized, user-friendly and easy to be implemented in the future, providing maps and scenarios of specific and multiple risk; to provide a vulnerability analysis for three historical churches (San Francisco del Baron, Las Hermanitas de la Providencia, La Matríz, made by various materials - masonry, concrete, wood and adobe - and located in different city sites) and for a building stock in the Cerro Cordillera (partially inside the UNESCO area), analyzing more than 200 constructions; to suggest guidelines for future urban planning and strengthening interventions. In the framework of the MAR VASTO Project, the most important hazards have been investigated carried out. With regard to seismic hazard, "state-of-the-art" information has been provided by Chilean partners and stakeholders, using materials of several studies and stored in original earthquake reports, local newspapers and magazines. The activities performed by the Italian team regarded the definition, for the city of Valparaiso, of earthquake scenarios and maps based on the neo

Design, aerodynamics and autonomy of the DelFly.

PubMed

de Croon, G C H E; Groen, M A; De Wagter, C; Remes, B; Ruijsink, R; van Oudheusden, B W

2012-06-01

One of the major challenges in robotics is to develop a fly-like robot that can autonomously fly around in unknown environments. In this paper, we discuss the current state of the DelFly project, in which we follow a top-down approach to ever smaller and more autonomous ornithopters. The presented findings concerning the design, aerodynamics and autonomy of the DelFly illustrate some of the properties of the top-down approach, which allows the identification and resolution of issues that also play a role at smaller scales. A parametric variation of the wing stiffener layout produced a 5% more power-efficient wing. An experimental aerodynamic investigation revealed that this could be associated with an improved stiffness of the wing, while further providing evidence of the vortex development during the flap cycle. The presented experiments resulted in an improvement in the generated lift, allowing the inclusion of a yaw rate gyro, pressure sensor and microcontroller onboard the DelFly. The autonomy of the DelFly is expanded by achieving (1) an improved turning logic to obtain better vision-based obstacle avoidance performance in environments with varying texture and (2) successful onboard height control based on the pressure sensor.

Mejoras en la exactitud del reloj de ángulo horario del telescopio de 2,15 mts de CASLEO

NASA Astrophysics Data System (ADS)

Aballay, J. L.; Pereyra, P. F.; Marún, A. H.

Para aumentar la exactitud en el control del ángulo horario del telescopio, se está implementando el uso de un reloj con una precisión de 1/100 seg. En conjunto con el encoder que otorga la posición con un acierto de 0,012 seg. de arco, se podrá implementar otro dígito en el reloj de ángulo horario con la posibilidad de ver las décimas. Esto, sumado a la precisión ya lograda en declinación, permitirá realizar offsets con mayor exactitud.

Carbon Concentration Excursions in Apatite Phenocrysts from the Cerro Galan Ignimbrite: A SIMS View into the Transient pre-Eruptive Volatile History of a Supervolcano

NASA Astrophysics Data System (ADS)

Boyce, J. W.; Hervig, R. L.

2006-12-01

In nearly all igneous rock compositions, apatite is the most abundant mineral that regularly incorporates significant quantities of volatile elements into its structure, making it a potentially useful tool for exploring magmatic processing of volatiles (as well as REEs, Sr, Nd, and Pb isotopes, all of which are typically abundant in apatite). We have developed an analytical protocol that permits measurement of C, H, F, S, and Cl in ~8μm diameter regions of apatite using the Cameca 6f SIMS. A primary Cs+ beam (4-10 nA) is used in conjunction with electron gun charge-compensation to sputter negative ions from polished sections and unpolished crystal faces mounted in volatile-free indium mounts. We operated at mass resolving powers sufficient to separate all potential interferences (such as ^{31}PH and 16O2 from ^{32}S, and 17O from 16OH). Quantifying the SIMS data requires a set of standards that are 1) homogeneous at the few-micron scale; and 2) well-calibrated with multiple, reliable, independent volatile content measurements. Using values combed from the literature and other unpublished sources, we have assembled a set of apatite standards, none of which are proven to meet either criteria. Nevertheless, these materials allow us to create calibration curves for all of the volatile elements listed above. Traverses across polished basal sections of apatite phenocrysts from the ~1000 km3 Cerro Galan ignimbrite, Argentina (courtesy of C. Schirnick) yield the following results: Apatites are fluorine-rich, and contain significant and reproducible intracrystalline variations in C, H, S, and Cl. Positive carbon concentration excursions (up to 360 ppm) are factors of 2-7 greater than apatite baseline concentrations (40-60 ppm), the largest of which correlate with position in different grains. In the majority of the traverses, these carbon excursions also correlate spatially with 25-30% increases in sulfur concentration. We suggest that these dramatic increases in carbon

Case Study: del Amo Bioventing

EPA Science Inventory

The attached presentation discusses the fundamentals of bioventing in the vadose zone. The basics of bioventing are presented. The experience to date with the del Amo Superfund Site is presented as a case study.

Percepcion de los profesores universitarios acerca del concepto cultura cientifica y de sus implicaciones en el nuevo bachillerato del Recinto de Rio Piedras de la Universidad de Puerto Rico

NASA Astrophysics Data System (ADS)

Ramos Pastrana, Nilsa

El Senado Academico del Recinto de Rio Piedras de la Universidad de Puerto Rico aprobo en el ano academico 2005-2006 la Certificacion 46, que contiene los lineamientos de un nuevo bachillerato. Este nuevo bachillerato introdujo cambios significativos en el curriculo tradicional. Entre ellos se encuentra la reduccion del componente de educacion general y el de Ciencias Biologicas en particular. La reduccion de creditos en el componente de Ciencias Biologicas ha obligado a reevaluar el concepto de cultura cientifica que desarrollan esos cursos. El proposito del estudio consistio en auscultar las percepciones de los profesores de las Facultades de Administracion de Empresas, Humanidades, Ciencias Sociales, Ciencias Naturales, Educacion y Estudios Generales del Recinto de Rio Piedras de la Universidad de Puerto Rico en torno al concepto de cultura cientifica, los contenidos disciplinares del curso de Ciencias Biologicas y la reduccion de creditos en el nuevo bachillerato. Las preguntas que guiaron la investigacion fueron: ¿cuales son las percepciones que tienen los profesores de las Facultades de Administracion de Empresas, Ciencias Sociales, Estudios Generales, Ciencias Naturales, Humanidades y Educacion, en torno al concepto de cultura cientifica y los contenidos disciplinares del curso de Ciencias Biologicas? ¿cuales son las percepciones que tienen los profesores de Ciencias Biologicas en torno al concepto cultura cientifica y los contenidos disciplinares del curso de Ciencias Biologicas? ¿existen diferencias significativas por facultad, genero, experiencia, rango y nombramiento en las percepciones que tienen los profesores del Recinto de Rio Piedras de la Universidad de Puerto Rico sobre los elementos que caracterizan la cultura cientifica y los contenidos biologicos que deben tener los egresados del Recinto? ¿que implicaciones curriculares tienen estos testimonios en el desarrollo del concepto de cultura cientifica en el nuevo bachillerato? Para realizar la

An evaluation of Delaware's DelTrac program : building an integrated transportation management system

DOT National Transportation Integrated Search

2004-06-01

The DelTrac deployment experience included both successes and unmet challenges. Programmatically, the DelTrac approach to managing ITS has been successful at creating a great deal of integration and cooperation between organizations at DelDOT. Stakeh...

El uso de la neuromodulación para el tratamiento del temblor

PubMed Central

Bendersky, Damián; Ajler, Pablo; Yampolsky, Claudio

2014-01-01

Introducción: El temblor puede ser un desorden incapacitante y el tratamiento de primera línea para estos pacientes es farmacológico. Sin embargo, este tratamiento puede llevar a una reducción satisfactoria del temblor en sólo el 50% de los pacientes con temblor esencial. La talamotomía era el tratamiento de elección para el temblor refractario al tratamiento médico hasta que comenzó a utilizarse la estimulación cerebral profunda (ECP) del núcleo ventral intermedio (Vim) del tálamo. En la actualidad, raramente se realiza la talamotomía. Métodos: Este artículo es una revisión no sistemática de las indicaciones, resultados, parámetros de programación y técnica quirúrgica de la ECP del Vim para el tratamiento del temblor. Resultados: Aunque los resultados clínicos son similares usando la talamotomía o la ECP del Vim, la primera causa más efectos adversos que la última. Además, la ECP puede ser usada bilateralmente, mientras que la talamotomía tiene un alto riesgo de causar disartria cuando se realiza de ambos lados. La ECP del Vim logró una adecuada mejoría del temblor en varias series de pacientes con temblor causado por temblor esencial, enfermedad de Parkinson o esclerosis múltiple. Además del Vim, hay otros blancos que están siendo usados por varios autores, tales como la zona incerta y las radiaciones prelemniscales. Conclusión: La ECP del Vim es un tratamiento útil para el temblor incapacitante refractario al tratamiento médico. Es esencial realizar una precisa selección de pacientes, así como utilizar una técnica quirúrgica correcta. Aún se desconoce el mejor blanco estereotáctico para el temblor, aunque el Vim es el más usado. PMID:25165613

CHEK2 1100delC and male breast cancer in the Netherlands.

PubMed

Wasielewski, Marijke; den Bakker, Michael A; van den Ouweland, Ans; Meijer-van Gelder, Marion E; Portengen, Henk; Klijn, Jan G M; Meijers-Heijboer, Hanne; Foekens, John A; Schutte, Mieke

2009-07-01

Mutations in the breast cancer susceptibility genes BRCA1, BRCA2, and CHEK2 are known risk factors for female breast cancer. Mutations in BRCA1 and BRCA2 also are associated with male breast cancer (MBC). Similarly, it had been suggested in the original CHEK2 identification report that the CHEK2 1100delC mutation confers an increased risk for MBC. Here, we have evaluated the risk of CHEK2 1100delC for MBC by genotyping CHEK2 1100delC in 23 familial and 71 unselected Dutch MBC cases. None of the 23 familial MBC cases carried the CHEK2 1100delC mutation. In contrast, CHEK2 1100delC was present in 3 of the 71 (4.2%) unselected MBC cases, which was significantly more prevalent than the 1.1% Dutch population frequency assessed in 1,692 individuals (P = 0.05, OR = 4.1, 95% CI 1.2-14.3). Our data suggest that, in the Netherlands, CHEK2 1100delC is associated with an increased risk for MBC.

Field measurements of del13C in ecosystem respiration

NASA Astrophysics Data System (ADS)

van Asperen, Hella; Sabbatini, Simone; Nicolini, Giacomo; Warneke, Thorsten; Papale, Dario; Notholt, Justus

2014-05-01

Stable carbon isotope del13C-measurements are extensively used to study ecological and biogeochemical processes in ecosystems. Above terrestrial ecosystems, atmospheric del13C can vary largely due to photosynthetic fractionation. Photosynthetic processes prefer the uptake of the lighter isotope 12C (in CO2), thereby enriching the atmosphere in 13C and depleting the ecosystem carbon. At night, when ecosystem respiratory fluxes are dominant, 13C-depleted CO2 is respired and thereby depletes the atmospheric del13C-content. Different ecosystems and different parts of one ecosystem (type of plant, leaves, and roots) fractionate and respire with a different del13C-ratio signature. By determining the del13C-signature of ecosystem respiration in temporal and spatial scale, an analysis can be made of the composition of respiratory sources of the ecosystem. A field study at a dry cropland after harvest (province of Viterbo, Lazio, Italy) was performed in the summer of 2013. A FTIR (Fourier Transform Infrared Spectrometer) was set up to continuously measure CO2-, CH4-, N2O-, CO- and del13C-concentrations. The FTIR was connected to 2 different flux measurements systems: a Flux Gradient system (sampling every half hour at 1.3m and 4.2m) and 2 flux chambers (measured every hour), providing a continuous data set of the biosphere-atmosphere gas fluxes and of the gas concentrations at different heights. Keeling plot intercept values of respiratory CO2, measured by the Flux Gradient system at night, were determined to be between -25‰ and -20‰. Keeling plot intercept values of respiratory CO2, measured by the flux chamber system, varied between -24‰ and -29‰, and showed a clear diurnal pattern, suggesting different (dominant) respiratory processes between day and night.

A search for Potential Impact Sites in Southern Argentina

NASA Astrophysics Data System (ADS)

Rocca, M. C. L.

The Southern part of Argentina is composed of five Provinces; Tierra del Fuego, Santa Cruz, Chubut, Rio Negro and Neuquen. A search for potential impact sites was performed by the author through the examination of 76 color LANDSAT satellite images ( 1:250,000 - resolution = 250 meters ) at the Instituto Geografico Militar ( IGM ) of Buenos Aires city. When a potential candidate was found a more detailed study of the site was done. If available the radar X-SAR satellite images of the Deutsche Forschungsanstalt fur Luft-und Raumfahrt, (DLR), Berlin, Germany , were also examined. The final step was to perform a review of the available published geologic information of each site at the Servicio Geologico y Minero Argentino ( SEGEMAR ), ( =Geological Survey of Argentina ), in Buenos Aires. The resulting catalogue contains information about sites where possible simple crater or complex impact structures could be present. Each case demands future detailed and `in situ' research by an impact cratering specialist. --Tierra del Fuego: TF1 ) Ushuaia 5569-II, No 218. Cerro Taarsh, Estancia San Justo. Possible complex structure. Semi-circular area of concentric low ridges. Estimated diameter : 12 km. Probably very eroded. --Santa Cruz: SC1 ) Gobernador Gregores 4969-I, No 127. Estancia La Aragonesa Possible eroded complex structure. Circular area of low ridges, estimated diameter: 10 km.. Bull's eye like morphology. SC2 ) Gobernador Gregores 4969-I, No 127. Gran Altiplanicie Central. Possible simple crater in basalts. Diameter: 1 km.. SC3 ) Tres Lagos 4972-IV, No 106. Meseta del Bagual Chico. Possible perfectly circular simple crater in basalts. Diameter: 1.0 km.. SC4 )Paso Rio Bote 5172-II, No 20. Rio Pelque, Ruta Provincial No 5. A circular bowl-shaped structure is present on fluvial deposits of pleistocenic age. Diameter: 3.5 km.. SC5 ) Caleta Olivia 4769-II, No 28. North of Cerro Doce Grande. Possible complex structure of concentric circular rings of ridges. SC6 ) Caleta

[Strengths and future of the Revista Médica del Instituto Mexicano del Seguro Social].

PubMed

Fajardo-Dolci, Germán

2014-01-01

The journals of medicine arose as a communication tool more than 200 years ago. At the beginning, their nature was local; later, their aim was to spread medical information along the nation; and, finally, they sought to reach the world distribution. The Revista Médica del Instituto Mexicano del Seguro Social was published for the first time 52 years ago, and it has walked its way from local to international distribution. This journal has 23 000 subscribers, it is included in Medline and it reached a 0.112 SCImago Journal Rank in 2012. Its website receives around 200 000 visits monthly and 45 % are foreign visits. In the future, the peer review system is going to be strengthened, and the journal is going to offer audio, video, and applications to reinforce interactive participation between authors, readers in order to reach modernity and draw young new attention.

Coseismic Deformations Associated with the M=7.2, April 04, 2010, El Mayor-Cucapah Earthquake, Observed from Leveling Survey, Geotechnical Instruments and Water Level Changes in the Mexicali Valley

NASA Astrophysics Data System (ADS)

Glowacka, E.; Robles, B.; Vázquez, R.; Sarychikhina, O.; Suárez-Vidal, F.; Ramirez, J.; Nava Pichardo, F. A.; Farfan, F.; Diaz de Cossio, G.

2010-12-01

A first order, second class leveling survey in the Mexicali Valley had been just finished in February 2010, for a project carried out by CICESE (Center for Scientific Research and Higher Education of Ensenada), IMTA (Mexican Institute of Water Technology) and CONAGUA (National Water Comission). Immediately after the M=7.2 earthquake the survey was repeated along 240 km of the profiles in the area of the Cerro Prieto pull-apart basin. The leveling started at the LN00 GPS monument in La Puerta. Overall, an uplift of about 30 cm towards the NE, along the 38 km line, in direction SW-NE is observed with larger gradient to the South of the area. Three subsidence bowls differ from this general pattern. One, south from Ejido Saltillo, with the relative subsidence of 19 cm (considering the displacement at LN00 as zero subsidence), probably reflects subsidence of the Saltillo-Guerrero graben; the second, with a subsidence of 23 cm, is situated south from Ejido Nuevo Leon and can be related to the subsidence triggered by the earthquake in the production area of Cerro Prieto IV. For the third one, with relative depth of 36 cm, situated close to Zacamoto, the southeastern limit cannot be determined, so only a comparison with other methods can explain the origin of this anomaly. All the subsidence bowls are associated with liquefaction observed in the area, with more liquefaction observed close to Zacamoto. Since 1996, CICESE has been operating a network of geotechnical instruments (REDECVAM) for continuous recording of deformation related to tectonic (seismic and interseismic) phenomena, as well as anthropogenic deformation caused by the deep fluid extraction at the Cerro Prieto Geothermal Field. The instruments are installed along the faults which limit the Cerro Prieto pull-apart basin at a distance from 8 to 15 km from the epicenter. Coseismic step-like groundwater level changes ranging from 0.4 to 5.0 meters were recorded at 4 wells in the Cerro Prieto Pull apart

Pastoral del Nino: Bringing the Abundant Life to Paraguayan Children

ERIC Educational Resources Information Center

Austin, Ann Berghout; Aquino, Cyle; Burro, Elizabeth

2007-01-01

Pastoral del Nino is transforming children's lives in rural Paraguay. Part of Pastoral Social (Catholic Social Services), Pastoral del Nino's primary focus is to bring "vida en abundancia" (the abundant life) to families by ensuring that mothers survive childbirth and children reach their first birthdays. In addition, the organization…

Perk Ablation Ameliorates Myelination in S63del-Charcot–Marie–Tooth 1B Neuropathy

PubMed Central

Musner, Nicolò; Sidoli, Mariapaola; Zambroni, Desireè; Del Carro, Ubaldo; Ungaro, Daniela; D’Antonio, Maurizio; Feltri, Maria L.

2016-01-01

In peripheral nerves, P0 glycoprotein accounts for more than 20% of myelin protein content. P0 is synthesized by Schwann cells, processed in the endoplasmic reticulum (ER) and enters the secretory pathway. However, the mutant P0 with S63 deleted (P0S63del) accumulates in the ER lumen and induces a demyelinating neuropathy in Charcot–Marie–Tooth disease type 1B (CMT1B)–S63del mice. Accumulation of P0S63del in the ER triggers a persistent unfolded protein response. Protein kinase RNA-like endoplasmic reticulum kinase (PERK) is an ER stress sensor that phosphorylates eukaryotic initiation factor 2 alpha (eIF2alpha) in order to attenuate protein synthesis. We have shown that increasing phosphophorylated-eIF2alpha (P-eIF2alpha) is a potent therapeutic strategy, improving myelination and motor function in S63del mice. Here, we explore the converse experiment: Perk haploinsufficiency reduces P-eIF2alpha in S63del nerves as expected, but surprisingly, ameliorates, rather than worsens S63del neuropathy. Motor performance and myelin abnormalities improved in S63del//Perk+/− compared with S63del mice. These data suggest that mechanisms other than protein translation might be involved in CMT1B/S63del neuropathy. In addition, Perk deficiency in other cells may contribute to demyelination in a non–Schwann-cell autonomous manner. PMID:27095827

Comparison of 36Cl and 3He measurements in glacial surfaces on the tropical Altiplano (Cerro Tunupa volcano, 20°S)

NASA Astrophysics Data System (ADS)

Schimmelpfennig, Irene; Blard, Pierre-Henri; Lavé, Jérôme; Benedetti, Lucilla; Aster Team

2016-04-01

The combination of two or more cosmogenic nuclides measured in the same rock samples allow complex landscape exposure histories to be quantified, due to the nuclide-specific production and decay rates. In supposedly simple exposure scenarios, such as moraine chronologies, the use of more than one nuclide can also help identify outliers caused by geomorphological bias (e.g. "inheritance") or analytical problems (e.g. nuclide loss or contamination during chemical extraction). The two cosmogenic in situ nuclides 3He and 36Cl are potentially very useful to be simultaneously measured in quartz-lacking lithologies, but their application is more challenging than that of combined 10Be and 26Al measurements, which are routinely employed in quartz-bearing rocks. This is, amongst other things, because the production of 3He and 36Cl depend on various compositional factors. Therefore, 3He and 36Cl have rarely been measured in the same samples so far. Here, we present 36Cl measurements in plagioclases extracted from four moraine boulders and one roche moutonnée on the southern flank of Cerro Tunupa volcano, located in the tropical Bolivian Andes (3800-4500 m, 20°S). In pyroxenes of these samples, 3He has previously been measured to gain insights into the local deglaciation history and climate conditions about 15 kyr ago during the Lake Tauca highstand (Blard et al., 2009, 2013). The ages calculated from the measured 3He and 36Cl concentrations of the 5 samples range from 12 kyr to 180 kyr and are generally in good agreement. The good age agreement of a boulder surface (TU-1C) that is significantly older than the other boulder ages from this moraine confirm the suspicion, that it was exposed to cosmic radiation previous to its last deposition (Blard et al., 2009, 2013). In contrast, the 36Cl age of the roche moutonnée surface (TU2) is significantly younger than the corresponding 3He age, but fits well with the adjacent moraine mean age. It thus arises the question if the 3He

Multiplex pyrosequencing of InDel markers for forensic DNA analysis.

PubMed

Bus, Magdalena M; Karas, Ognjen; Allen, Marie

2016-12-01

The capillary electrophoresis (CE) technology is commonly used for fragment length separation of markers in forensic DNA analysis. In this study, pyrosequencing technology was used as an alternative and rapid tool for the analysis of biallelic InDel (insertion/deletion) markers for individual identification. The DNA typing is based on a subset of the InDel markers that are included in the Investigator ® DIPplex Kit, which are sequenced in a multiplex pyrosequencing analysis. To facilitate the analysis of degraded DNA, the polymerase chain reaction (PCR) fragments were kept short in the primer design. Samples from individuals of Swedish origin were genotyped using the pyrosequencing strategy and analysis of the Investigator ® DIPplex markers with CE. A comparison between the pyrosequencing and CE data revealed concordant results demonstrating a robust and correct genotyping by pyrosequencing. Using optimal marker combination and a directed dispensation strategy, five markers could be multiplexed and analyzed simultaneously. In this proof-of-principle study, we demonstrate that multiplex InDel pyrosequencing analysis is possible. However, further studies on degraded samples, lower DNA quantities, and mixtures will be required to fully optimize InDel analysis by pyrosequencing for forensic applications. Overall, although CE analysis is implemented in most forensic laboratories, multiplex InDel pyrosequencing offers a cost-effective alternative for some applications. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

[Trattamento del disturbo da uso di alcol da un punto di vista psicologico].

PubMed

Coriale, Giovanna; Fiorentino, Daniela; De Rosa, Francesca; Solombrino, Simona; Scalese, Bruna; Ciccarelli, Rosaria; Attilia, Fabio; Vitali, Mario; Musetti, Alessia; Fiore, Marco; Ceccanti, Mauro

2018-01-01

RIASSUNTO. L'elaborazione del piano di trattamento rappresenta un momento molto delicato e complesso del processo terapeutico del disturbo da abuso di alcol (DUA). È la fase in cui le informazioni raccolte da un'équipe di professionisti (medici, psicologi e assistenti sociali) (modello bio-psico-sociale del DUA) vengono messe insieme per decidere il percorso terapeutico più adatto. Per quanto riguarda la parte psicologica, è di notevole importanza scegliere un trattamento clinico in grado di ridurre al minimo la mancata adesione al trattamento e, per i soggetti che rimangono in trattamento, di garantirne l'efficacia. Se da una parte, le tecniche psicoanalitiche e comportamentali hanno fornito le basi della terapia psicologica dell'alcolismo, dall'altra, gli approcci basati sull'evidenza scientifica sono stati elaborati a partire dai principi del colloquio motivazionale e della terapia cognitivo-comportamentale. In questo articolo viene fornita una panoramica dei trattamenti che sono risultati più efficaci nel trattare il DUA e delle modalità temporali più adeguate per monitorare l'efficacia del trattamento.

Multi-InDel Analysis for Ancestry Inference of Sub-Populations in China

PubMed Central

Sun, Kuan; Ye, Yi; Luo, Tao; Hou, Yiping

2016-01-01

Ancestry inference is of great interest in diverse areas of scientific researches, including the forensic biology, medical genetics and anthropology. Various methods have been published for distinguishing populations. However, few reports refer to sub-populations (like ethnic groups) within Asian populations for the limitation of markers. Several InDel loci located very tightly in physical positions were treated as one marker by us, which is multi-InDel. The multi-InDel shows potential as Ancestry Inference Marker (AIM). In this study, we performed a genome-wide scan for multi-InDels as AIM. After examining the FST distributions in the 1000 Genomes Database, 12 candidates were selected and validated for eastern Asian populations. A multiplexed assay was developed as a panel to genotype 12 multi-InDel markers simultaneously. Ancestry component analysis with STRUCTURE and principal component analysis (PCA) were employed to estimate its capability for ancestry inference. Furthermore, ancestry assignments of trial individuals were conducted. It proved to be very effective when 210 samples from Han and Tibetan individuals in China were tested. The panel consisting of multi-InDel markers exhibited considerable potency in ancestry inference, and was suggested to be applied in forensic practices and genetic population studies. PMID:28004788

Observaciones del CH interestelar y el continuo en 3,3 GHz

NASA Astrophysics Data System (ADS)

Olano, C. A.; Combi, J. A.; Pöppel, W.; Benaglia, P.; Sanz, A. J.; Bava, J. A.

Se informa sobre el proyecto que se lleva a cabo en el IAR con el propósito de observar las líneas hiperfinas del estado fundamental del CH y el continuo en la banda de 3,3 GHz. El nuevo receptor construído en nuestro laboratorio para tal fin se instaló sobre uno de los radiotelescopios, funcionando conjuntamente con los sistemas de procesamiento actuales del IAR. Los resultados de las primeras observaciones, realizadas tanto en las líneas espectrales como en el continuo sobre fuentes conocidas, fueron satisfactorios.

Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

PubMed

Muranen, Taru A; Greco, Dario; Blomqvist, Carl; Aittomäki, Kristiina; Khan, Sofia; Hogervorst, Frans; Verhoef, Senno; Pharoah, Paul D P; Dunning, Alison M; Shah, Mitul; Luben, Robert; Bojesen, Stig E; Nordestgaard, Børge G; Schoemaker, Minouk; Swerdlow, Anthony; García-Closas, Montserrat; Figueroa, Jonine; Dörk, Thilo; Bogdanova, Natalia V; Hall, Per; Li, Jingmei; Khusnutdinova, Elza; Bermisheva, Marina; Kristensen, Vessela; Borresen-Dale, Anne-Lise; Investigators, Nbcs; Peto, Julian; Dos Santos Silva, Isabel; Couch, Fergus J; Olson, Janet E; Hillemans, Peter; Park-Simon, Tjoung-Won; Brauch, Hiltrud; Hamann, Ute; Burwinkel, Barbara; Marme, Frederik; Meindl, Alfons; Schmutzler, Rita K; Cox, Angela; Cross, Simon S; Sawyer, Elinor J; Tomlinson, Ian; Lambrechts, Diether; Moisse, Matthieu; Lindblom, Annika; Margolin, Sara; Hollestelle, Antoinette; Martens, John W M; Fasching, Peter A; Beckmann, Matthias W; Andrulis, Irene L; Knight, Julia A; Investigators, kConFab/Aocs; Anton-Culver, Hoda; Ziogas, Argyrios; Giles, Graham G; Milne, Roger L; Brenner, Hermann; Arndt, Volker; Mannermaa, Arto; Kosma, Veli-Matti; Chang-Claude, Jenny; Rudolph, Anja; Devilee, Peter; Seynaeve, Caroline; Hopper, John L; Southey, Melissa C; John, Esther M; Whittemore, Alice S; Bolla, Manjeet K; Wang, Qin; Michailidou, Kyriaki; Dennis, Joe; Easton, Douglas F; Schmidt, Marjanka K; Nevanlinna, Heli

2017-05-01

CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk associated with CHEK2*1100delC is modified by other genetic factors in a multiplicative fashion. We have investigated this empirically using data from the Breast Cancer Association Consortium (BCAC). Using genotype data from 39,139 (624 1100delC carriers) BC patients and 40,063 (224) healthy controls from 32 BCAC studies, we analyzed the combined risk effects of CHEK2*1100delC and 77 common variants in terms of a polygenic risk score (PRS) and pairwise interaction. The PRS conferred odds ratios (OR) of 1.59 (95% CI: 1.21-2.09) per standard deviation for BC for CHEK2*1100delC carriers and 1.58 (1.55-1.62) for noncarriers. No evidence of deviation from the multiplicative model was found. The OR for the highest quintile of the PRS was 2.03 (0.86-4.78) for CHEK2*1100delC carriers, placing them in the high risk category according to UK NICE guidelines. The OR for the lowest quintile was 0.52 (0.16-1.74), indicating a lifetime risk close to the population average. Our results confirm the multiplicative nature of risk effects conferred by CHEK2*1100delC and the common susceptibility variants. Furthermore, the PRS could identify carriers at a high lifetime risk for clinical actions.Genet Med advance online publication 06 October 2016.

Submillimeter Atmospheric Transparency at Maunakea, at the South Pole, and at Chajnantor

NASA Astrophysics Data System (ADS)

Radford, Simon J. E.; Peterson, Jeffery B.

2016-07-01

For a systematic assessment of submillimeter observing conditions at different sites, we constructed tipping radiometers to measure the broad band atmospheric transparency in the window around 350 μm wavelength. The tippers were deployed on Maunakea, Hawaii, at the South Pole, and in the vicinity of Cerro Chajnantor in northern Chile. Identical instruments permit direct comparison of these sites. Observing conditions at the South Pole and in the Chajnantor area are better than on Maunakea. Simultaneous measurements with two tippers demonstrate conditions at the summit of Cerro Chajnantor are significantly better than on the Chajnantor plateau.

The Cuernos del Paine mountains in Torres del Paine National Park, Chile, during NASA's AirSAR 2004 campaign

NASA Image and Video Library

2004-03-11

The Cuernos del Paine mountains in Torres del Paine National Park, Chile, during NASA's AirSAR 2004 campaign. AirSAR 2004 is a three-week expedition in Central and South America by an international team of scientists that is using an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR), located onboard NASA's DC-8 airborne laboratory. Scientists from many parts of the world are combining ground research with NASA's AirSAR technology to improve and expand on the quality of research they are able to conduct. Founded in 1959, Torres del Paine National Park encompasses 450,000 acres in the Patagonia region of Chile. This region is being studied by NASA using a DC-8 equipped with an Airborne Synthetic Aperture Radar (AirSAR) developed by scientists from NASA’s Jet Propulsion Laboratory. This is a very sensitive region that is important to scientists because the temperature has been consistently rising causing a subsequent melting of the region’s glaciers. AirSAR will provide a baseline model and unprecedented mapping of the region. This data will make it possible to determine whether the warming trend is slowing, continuing or accelerating. AirSAR will also provide reliable information on ice shelf thickness to measure the contribution of the glaciers to sea level.

Earth Observations

NASA Image and Video Library

2010-08-22

ISS024-E-012425 (22 Aug. 2010) --- This photograph, featuring a landscape in the central Andes mountains near the Chile/Argentina border dominated by numerous volcanoes and associated landforms, was photographed by an Expedition 24 crew member on the International Space Station. Layers of older sedimentary rocks are visible to the southeast (upper right). Many of the volcanic cones show grooves eroded by water to form gullies. Such erosion has occurred since the host volcano was built up, indicating that most volcanoes in this view have been inactive for centuries or millennia. A few volcanoes exhibit much less erosion, and even show tongues of recent, dark lava flows (top left). According to scientists, two of these volcanoes, Cerro el Condor and Peinado have likely erupted within approximately the last 12,000 years (the Holocene Epoch). Also visible in the image is the world’s highest active volcano, Nevado Ojos del Salado, with a summit at 6,887 meters above sea level. The most recent confirmed eruption of this volcano has been dated to 700 (approximately 300 years), but minor eruptive activity may have occurred as recently as 1993. Stratovolcanoes such as Cerro el Condor, Peinado, and Nevado Ojos del Salado are formed partly by buildup of lava flows and partly by buildup of explosively vented material dropping back down onto the surface. One type of material associated with explosive eruptions is welded tuff, which is formed by molten and fragmented rock that accumulates on the ground and later solidifies. A large tuff sheet is visible at top left. Formed very rapidly, these sheets have been termed “instant landscapes.” So active has the Andean volcanic system been that the origin of many of the tuffs in the Andes cannot be pinpointed since source vents have been overprinted by subsequent volcanic events. The volcanic landscape also shows that the erosive work of rivers—and glaciers repeatedly in the recent past—is slower than the opposite processes

Modelo semi-empírico de protuberancia solar a partir del diagnóstico de densidades

NASA Astrophysics Data System (ADS)

Cirigliano, D.; Vial, J. C.; Rovira, M.

A partir de la observación del espectro del quintuplete de C III alrededor de 1175 Å, se ha realizado el diagnóstico de la densidad y presión electrónica, basado en el cálculo del cociente de las intensidades observadas. Una vez establecida la densidad electrónica, y con el cálculo de las velocidades Doppler, hemos investigado el flujo de masa en la protuberancia en función de la temperatura. Estableciendo como hipótesis la conservación del número de partículas que ingresan y salen del cuerpo de la protuberancia, se investiga la variación del área de un tubo de flujo semi-empírico en función de la temperatura. A partir de dicho diagnóstico, se examina el comportamiento del radio del tubo magnético en función de la temperatura, los que dan cuenta de la abertura de las líneas de campo magnético que confinan el plasma y de la divergencia del campo magnético en diferentes alturas de la atmósfera solar.

Uso Del Condón en Adolescentes Nahuas, un Modelo Explicativo.

PubMed

Tirado, María de Los Ángeles Meneses; Benavides-Torres, Raquel A; Navarro, Sergio Meneses; de la Colina, Juan Antonio Doncel; Rodríguez, Dora Julia Onofre; Hernández, Francisco Javier Baéz

2018-03-01

En México, la población indígena supera los siete millones de habitantes, en Puebla el grupo más representativo es el Náhuatl. Sin embargo, las condiciones de vida, salud, educación y transporte son precarias para esta población. En los adolescentes, las responsabilidades como el matrimonio, la familia y los compromisos ante la comunidad, favorecen conductas de riesgo sexual que dificultan su desarrollo económico, social y reproductivo. El objetivo fue proponer un modelo explicativo del uso del condón en adolescentes nahuas. Método. Bajo el marco de la teoría social cognitiva, el concepto de valores culturales de Leininger y el proceso de la sustracción teórica, se desarrolló este artículo. Se muestran las relaciones del modelo con las proposiciones y los factores que influyen en el uso del condón para este grupo específico. Finalmente, el modelo explica las variables de interés, los niveles de abstracción y las relaciones entre sí en el contexto náhuatl. El siguiente paso será implementar los indicadores empíricos para conocer el grado de influencia de los factores personales y ambientales hacia el uso del condón en adolescentes nahuas. Resultados que aportarán información para el desarrollo del conocimiento en enfermería y la reducción de riesgo sexual de esta población.

Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications.

PubMed

Muranen, Taru A; Greco, Dario; Fagerholm, Rainer; Kilpivaara, Outi; Kämpjärvi, Kati; Aittomäki, Kristiina; Blomqvist, Carl; Heikkilä, Päivi; Borg, Ake; Nevanlinna, Heli

2011-09-20

Checkpoint kinase 2 (CHEK2) is a moderate penetrance breast cancer risk gene, whose truncating mutation 1100delC increases the risk about twofold. We investigated gene copy-number aberrations and gene-expression profiles that are typical for breast tumors of CHEK2 1100delC-mutation carriers. In total, 126 breast tumor tissue specimens including 32 samples from patients carrying CHEK2 1100delC were studied in array-comparative genomic hybridization (aCGH) and gene-expression (GEX) experiments. After dimensionality reduction with CGHregions R package, CHEK2 1100delC-associated regions in the aCGH data were detected by the Wilcoxon rank-sum test. The linear model was fitted to GEX data with R package limma. Genes whose expression levels were associated with CHEK2 1100delC mutation were detected by the bayesian method. We discovered four lost and three gained CHEK2 1100delC-related loci. These include losses of 1p13.3-31.3, 8p21.1-2, 8p23.1-2, and 17p12-13.1 as well as gains of 12q13.11-3, 16p13.3, and 19p13.3. Twenty-eight genes located on these regions showed differential expression between CHEK2 1100delC and other tumors, nominating them as candidates for CHEK2 1100delC-associated tumor-progression drivers. These included CLCA1 on 1p22 as well as CALCOCO1, SBEM, and LRP1 on 12q13. Altogether, 188 genes were differentially expressed between CHEK2 1100delC and other tumors. Of these, 144 had elevated and 44, reduced expression levels.Our results suggest the WNT pathway as a driver of tumorigenesis in breast tumors of CHEK2 1100delC-mutation carriers and a role for the olfactory receptor protein family in cancer progression. Differences in the expression of the 188 CHEK2 1100delC-associated genes divided breast tumor samples from three independent datasets into two groups that differed in their relapse-free survival time. We have shown that copy-number aberrations of certain genomic regions are associated with CHEK2 mutation 1100delC. On these regions, we identified

Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications

PubMed Central

2011-01-01

Introduction Checkpoint kinase 2 (CHEK2) is a moderate penetrance breast cancer risk gene, whose truncating mutation 1100delC increases the risk about twofold. We investigated gene copy-number aberrations and gene-expression profiles that are typical for breast tumors of CHEK2 1100delC-mutation carriers. Methods In total, 126 breast tumor tissue specimens including 32 samples from patients carrying CHEK2 1100delC were studied in array-comparative genomic hybridization (aCGH) and gene-expression (GEX) experiments. After dimensionality reduction with CGHregions R package, CHEK2 1100delC-associated regions in the aCGH data were detected by the Wilcoxon rank-sum test. The linear model was fitted to GEX data with R package limma. Genes whose expression levels were associated with CHEK2 1100delC mutation were detected by the bayesian method. Results We discovered four lost and three gained CHEK2 1100delC-related loci. These include losses of 1p13.3-31.3, 8p21.1-2, 8p23.1-2, and 17p12-13.1 as well as gains of 12q13.11-3, 16p13.3, and 19p13.3. Twenty-eight genes located on these regions showed differential expression between CHEK2 1100delC and other tumors, nominating them as candidates for CHEK2 1100delC-associated tumor-progression drivers. These included CLCA1 on 1p22 as well as CALCOCO1, SBEM, and LRP1 on 12q13. Altogether, 188 genes were differentially expressed between CHEK2 1100delC and other tumors. Of these, 144 had elevated and 44, reduced expression levels. Our results suggest the WNT pathway as a driver of tumorigenesis in breast tumors of CHEK2 1100delC-mutation carriers and a role for the olfactory receptor protein family in cancer progression. Differences in the expression of the 188 CHEK2 1100delC-associated genes divided breast tumor samples from three independent datasets into two groups that differed in their relapse-free survival time. Conclusions We have shown that copy-number aberrations of certain genomic regions are associated with CHEK2 mutation

Max Brödel: his art, legacy, and contributions to neurosurgery through medical illustration.

PubMed

Patel, Smruti K; Couldwell, William T; Liu, James K

2011-07-01

Max Brödel is considered the father of modern medical illustration. This report reviews his contributions to neurosurgery as a medical illustrator. Max Brödel, a young artist from Leipzig, Germany, was hired at Johns Hopkins Hospital in 1894, where he illustrated an operative textbook of gynecology for Howard A. Kelly. Although Brödel did not have any formal medical training, he quickly acquired knowledge of anatomy, pathology, physiology, and surgery. Brödel's extraordinary illustrations were characterized by an aerial perspective that conveyed the surgeon's operative viewpoint and precise surgical anatomy. He masterfully incorporated tissue realism with cross-sectional anatomy to accentuate concepts while maintaining topographical accuracy. Brödel's reputation spread quickly and resulted in collaborations with prominent surgeons, such as Cushing, Halsted, and Dandy. Cushing, who also possessed artistic talent, became a pupil of Brödel and remained a very close friend. In 1911, Brödel was appointed the director of the Department of Art as Applied to Medicine at Johns Hopkins, the first academic department of its kind in the world. For the next several decades, he trained generations of renowned medical illustrators. Just as Osler, Halsted, and Cushing passed their skills and knowledge to future leaders of medicine and surgery, Brödel did the same for the field of medical illustration. The advancement of neurosurgical education has been greatly facilitated by Max Brödel's artistic contributions. His unique ability to synthesize art and medicine resulted in timeless illustrations that remain indispensable to surgeons. The art produced by his legacy of illustrators continues to flourish in neurosurgical literature today.

Genetic modifiers of CHEK2*1100delC associated breast cancer risk

PubMed Central

Muranen, Taru A.; Greco, Dario; Blomqvist, Carl; Aittomäki, Kristiina; Khan, Sofia; Hogervorst, Frans; Verhoef, Senno; Pharoah, Paul D.P.; Dunning, Alison M.; Shah, Mitul; Luben, Robert; Bojesen, Stig E.; Nordestgaard, Børge G.; Schoemaker, Minouk; Swerdlow, Anthony; García-Closas, Montserrat; Figueroa, Jonine; Dörk, Thilo; Bogdanova, Natalia V.; Hall, Per; Li, Jingmei; Khusnutdinova, Elza; Bermisheva, Marina; Kristensen, Vessela; Borresen-Dale, Anne-Lise; Peto, Julian; dos Santos Silva, Isabel; Couch, Fergus J.; Olson, Janet E.; Hillemans, Peter; Park-Simon, Tjoung-Won; Brauch, Hiltrud; Hamann, Ute; Burwinkel, Barbara; Marme, Frederik; Meindl, Alfons; Schmutzler, Rita K.; Cox, Angela; Cross, Simon S.; Sawyer, Elinor J.; Tomlinson, Ian; Lambrechts, Diether; Moisse, Matthieu; Lindblom, Annika; Margolin, Sara; Hollestelle, Antoinette; Martens, John W.M.; Fasching, Peter A.; Beckmann, Matthias W.; Andrulis, Irene L.; Knight, Julia A.; Anton-Culver, Hoda; Ziogas, Argyrios; Giles, Graham G.; Milne, Roger L.; Brenner, Hermann; Arndt, Volker; Mannermaa, Arto; Kosma, Veli-Matti; Chang-Claude, Jenny; Rudolph, Anja; Devilee, Peter; Seynaeve, Caroline; Hopper, John L.; Southey, Melissa C.; John, Esther M.; Whittemore, Alice S.; Bolla, Manjeet K.; Wang, Qin; Michailidou, Kyriaki; Dennis, Joe; Easton, Douglas F.; Schmidt, Marjanka K.; Nevanlinna, Heli

2016-01-01

Purpose CHEK2*1100delC is a founder variant in European populations conferring a 2–3 fold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk associated with CHEK2*1100delC is modified by other genetic factors in a multiplicative fashion. We have investigated this empirically using data from the Breast Cancer Association Consortium (BCAC). Methods With genotype data of 39,139 (624 1100delC carriers) BC patients and 40,063 (224) healthy controls from 32 BCAC studies, we analyzed the combined risk effects of CHEK2*1100delC and 77 common variants in terms of a polygenic risk score (PRS) and pairwise interaction. Results The PRS conferred an odds ratio (OR) of 1.59 [95% CI 1.21–2.09] per standard deviation for BC for CHEK2*1100delC carriers and 1.58 [1.55–1.62] for non-carriers. No evidence for deviation from the multiplicative model was found. The OR for the highest quintile of the PRS was 2.03 [0.86–4.78] for CHEK2*1100delC carriers placing them to the high risk category according to UK NICE guidelines. OR for the lowest quintile was 0.52 [0.16–1.74], indicating life-time risk close to population average. Conclusion Our results confirm the multiplicative nature of risk effects conferred by CHEK2*1100delC and the common susceptibility variants. Furthermore, the PRS could identify the carriers at a high life-time risk for clinical actions. PMID:27711073

Gödel metrics with chronology protection in Horndeski gravities

NASA Astrophysics Data System (ADS)

Geng, Wei-Jian; Li, Shou-Long; Lü, H.; Wei, Hao

2018-05-01

Gödel universe, one of the most interesting exact solutions predicted by General Relativity, describes a homogeneous rotating universe containing naked closed time-like curves (CTCs). It was shown that such CTCs are the consequence of the null energy condition in General Relativity. In this paper, we show that the Gödel-type metrics with chronology protection can emerge in Einstein-Horndeski gravity. We construct such exact solutions also in Einstein-Horndeski-Maxwell and Einstein-Horndeski-Proca theories.

Estrategia innovadora enfocada en parejas del mismo sexo para disminuir la infección del VIH en hombres Latinos

PubMed Central

Martinez, Omar; Wu, Elwin; Sandfort, Theo; Shultz, Andrew Z.; Capote, Jonathan; Chávez, Silvia; Moya, Eva; Dodge, Brian; Morales, Gabriel; Porras, Antonio; Ovejero, Hugo

2014-01-01

Resumen El VIH es un problema de salud importante dentro de la comunidad latina de los Estados Unidos. Gracias a los esfuerzos de prevención, los niveles de contagio entre los latinos se han mantenido estables por más de una década. Sin embargo, esta población sigue siendo afectada a niveles muy altos, en particular entre hombres que tienen sexo con hombres (HSH), de origen latino y que hablan principalmente el idioma español. Existen varios factores que contribuyen a la transmisión del VIH entre esta población, como son: el uso de drogas; la violencia dentro de la pareja; la presencia de infecciones de transmisión sexual; relaciones sexuales sin protección, dentro y fuera de la pareja; el evadir la búsqueda de recursos (prueba y tratamiento adecuado) por temor a ser discriminado o por su estatus migratorio; la escasez de recursos económicos o estado de pobreza y los patrones relacionados a la migración. En particular, Investigaciones Epidemiológicas de Comportamientos han determinado: cómo algunas dinámicas en parejas están directamente asociadas a los comportamientos sexuales de riesgos. En consecuencia, es necesaria mayor investigación para identificar esas dinámicas, y a su vez, realizar intervenciones dirigidas a la reducción de conductas de riesgo enfocadas en parejas de hombres del mismo sexo. En este escrito, se describe la importancia del uso de las relaciones de pareja como estrategia en la reducción de la trasmisión del VIH/SIDA en HSH de origen latino y que hablan principalmente el idioma español en los Estados Unidos. PMID:25580466

Determinacion de Caracteristicas Opticas del Telescopio OAN150

NASA Astrophysics Data System (ADS)

Galan, M. J.; Cobos, F. J.

1987-05-01

En el Observatorio de Calar Alto, en Almería, España, está ubicado un telescopio de 15O-cms de diámetro -construído por REOSC- perteneciente al Observatorio Astronómico Nacional, con sede en Madrid, España. La infraestructura técnica del OAN ha sido tradicionalmente débil y actualmente se está haciendo un esfuerzo por fortalecerla. Existe una información muy limitada del telescopio en general; de su óptica en particular se conocían los valores de los parámetros principales pero sin saber si éstos corresponden a valores teóricos ó de construcción. Por ello se consideró necesario iniciar una investigación para conocer en detalle los valores reales de las componentes ópticas del telescopio, obteniéndose algunos resultados de interés. El primario del telescopio OANl5O es aproximadamente F/3 y el siste ma en su conjunto es F/8.2, con su sistema corrector de campo. En términos generales, la imagen es satisfactoria en todo el campo y, sin sistema corrector, la imagen axial también es buena. En un futuro muy cercano se piensa diseñar instrumentación adicional para este telescopio. Conocer con mayor precisión sus características puede ser de gran utilidad para tal fin, pues se efectúan los cálculos considerando conjuntamente al telescopio y al instrumento.

Pseudomonas aeruginosa Reduces VX-809 Stimulated F508del-CFTR Chloride Secretion by Airway Epithelial Cells

PubMed Central

Stanton, Bruce A.; Coutermarsh, Bonita; Barnaby, Roxanna; Hogan, Deborah

2015-01-01

Background P. aeruginosa is an opportunistic pathogen that chronically infects the lungs of 85% of adult patients with Cystic Fibrosis (CF). Previously, we demonstrated that P. aeruginosa reduced wt-CFTR Cl secretion by airway epithelial cells. Recently, a new investigational drug VX-809 has been shown to increase F508del-CFTR Cl secretion in human bronchial epithelial (HBE) cells, and, in combination with VX-770, to increase FEV1 (forced expiratory volume in 1 second) by an average of 3-5% in CF patients homozygous for the F508del-CFTR mutation. We propose that P. aeruginosa infection of CF lungs reduces VX-809 + VX-770- stimulated F508del-CFTR Cl secretion, and thereby reduces the clinical efficacy of VX-809 + VX-770. Methods and Results F508del-CFBE cells and primary cultures of CF-HBE cells (F508del/F508del) were exposed to VX-809 alone or a combination of VX-809 + VX-770 for 48 hours and the effect of P. aeruginosa on F508del-CFTR Cl secretion was measured in Ussing chambers. The effect of VX-809 on F508del-CFTR abundance was measured by cell surface biotinylation and western blot analysis. PAO1, PA14, PAK and 6 clinical isolates of P. aeruginosa (3 mucoid and 3 non-mucoid) significantly reduced drug stimulated F508del-CFTR Cl secretion, and plasma membrane F508del-CFTR. Conclusion The observation that P. aeruginosa reduces VX-809 and VX-809 + VX-770 stimulated F508del CFTR Cl secretion may explain, in part, why VX-809 + VX-770 has modest efficacy in clinical trials. PMID:26018799

Pseudomonas aeruginosa Reduces VX-809 Stimulated F508del-CFTR Chloride Secretion by Airway Epithelial Cells.

PubMed

Stanton, Bruce A; Coutermarsh, Bonita; Barnaby, Roxanna; Hogan, Deborah

2015-01-01

P. aeruginosa is an opportunistic pathogen that chronically infects the lungs of 85% of adult patients with Cystic Fibrosis (CF). Previously, we demonstrated that P. aeruginosa reduced wt-CFTR Cl secretion by airway epithelial cells. Recently, a new investigational drug VX-809 has been shown to increase F508del-CFTR Cl secretion in human bronchial epithelial (HBE) cells, and, in combination with VX-770, to increase FEV1 (forced expiratory volume in 1 second) by an average of 3-5% in CF patients homozygous for the F508del-CFTR mutation. We propose that P. aeruginosa infection of CF lungs reduces VX-809 + VX-770- stimulated F508del-CFTR Cl secretion, and thereby reduces the clinical efficacy of VX-809 + VX-770. F508del-CFBE cells and primary cultures of CF-HBE cells (F508del/F508del) were exposed to VX-809 alone or a combination of VX-809 + VX-770 for 48 hours and the effect of P. aeruginosa on F508del-CFTR Cl secretion was measured in Ussing chambers. The effect of VX-809 on F508del-CFTR abundance was measured by cell surface biotinylation and western blot analysis. PAO1, PA14, PAK and 6 clinical isolates of P. aeruginosa (3 mucoid and 3 non-mucoid) significantly reduced drug stimulated F508del-CFTR Cl secretion, and plasma membrane F508del-CFTR. The observation that P. aeruginosa reduces VX-809 and VX-809 + VX-770 stimulated F508del CFTR Cl secretion may explain, in part, why VX-809 + VX-770 has modest efficacy in clinical trials.

Genomic profiling of CHEK2*1100delC-mutated breast carcinomas.

PubMed

Massink, Maarten P G; Kooi, Irsan E; Martens, John W M; Waisfisz, Quinten; Meijers-Heijboer, Hanne

2015-11-09

CHEK2*1100delC is a moderate-risk breast cancer susceptibility allele with a high prevalence in the Netherlands. We performed copy number and gene expression profiling to investigate whether CHEK2*1100delC breast cancers harbor characteristic genomic aberrations, as seen for BRCA1 mutated breast cancers. We performed high-resolution SNP array and gene expression profiling of 120 familial breast carcinomas selected from a larger cohort of 155 familial breast tumors, including BRCA1, BRCA2, and CHEK2 mutant tumors. Gene expression analyses based on a mRNA immune signature was used to identify samples with relative low amounts of tumor infiltrating lymphocytes (TILs), which were previously found to disturb tumor copy number and LOH (loss of heterozygosity) profiling. We specifically compared the genomic and gene expression profiles of CHEK2*1100delC breast cancers (n = 14) with BRCAX (familial non-BRCA1/BRCA2/CHEK2*1100delC mutated) breast cancers (n = 34) of the luminal intrinsic subtypes for which both SNP-array and gene expression data is available. High amounts of TILs were found in a relatively small number of luminal breast cancers as compared to breast cancers of the basal-like subtype. As expected, these samples mostly have very few copy number aberrations and no detectable regions of LOH. By unsupervised hierarchical clustering of copy number data we observed a great degree of heterogeneity amongst the CHEK2*1100delC breast cancers, comparable to the BRCAX breast cancers. Furthermore, copy number aberrations were mostly seen at low frequencies in both the CHEK2*1100delC and BRCAX group of breast cancers. However, supervised class comparison identified copy number loss of chromosomal arm 1p to be associated with CHEK2*1100delC status. In conclusion, in contrast to basal-like BRCA1 mutated breast cancers, no apparent specific somatic copy number aberration (CNA) profile for CHEK2*1100delC breast cancers was found. With the possible exception of copy

Geology of the Orcopampa 30 minute quadrangle, southern Peru with special focus on the evolution of the Chinchon and Huayta calderas

NASA Astrophysics Data System (ADS)

Swanson, Kirk Edward

The 30 minute Orcopampa quadrangle, southern Peru, was a site of several episodes of Neogene volcanism, hydrothermal activity and precious-metal mineralization. Lavas of pyroxene andesite and associated silicic tuffs of the early Miocene Santa Rosa volcanics are the remnants of stratovolcanoes overlying an irregular erosional surface developed on a transgressive Mesozoic marine succession. Major ash-flow volcanism then resulted in the 20.1 Ma Manto Tuff and the associated Chinchon caldera. Deep dissection, locally >2 km, has exposed the steep caldera margin, slide blocks and related (19.9 Ma) dikes. Flows and domes of hornblende-biotite dacite comprising the Sarpane volcanics were erupted between about 18.5--19.5 Ma over much of the northern part of the quadrangle. Early Miocene rocks were folded during the Quechua I tectonic event, and related ENE-trending normal faults host the 17.8 Ma Ag-Au veins of the Orcopampa district. Eruption of the ca. 11.6 Ma tuffs of Cerro Huayta and Cerro Hospicio resulted in formation of the Huayta caldera, nested within the northern part of the Chinchon caldera. Caldera formation was associated with, and followed by, the eruption of intermediate lavas of Cerro Sahuarque ( ca. 11.4 Ma) and the emplacement of rhyolite domes. The adularia-sericite type Au-Ag veins of Mina Shila were formed along the southern margin of the Huayta caldera several million years after collapse. The 7.3 Ma tuff of Laguna Pariguanas, erupted from vents northeast of the Huayta caldera, appears to be deformed; however, the 6.2 Ma tuff of Umachulco postdates Quechua II/III tectonism. Flows and domes of the ca. 7.2 Ma andesite of Cerro Aseruta were emplaced within the Huayta caldera, and approximately contemporaneous lavas of silicic to intermediate composition were erupted in the northern part of the quadrangle. A large area of largely barren acid-sulfate alteration (Chuchanne) formed within the Huayta caldera shortly after the eruption of the andesite of Cerro

Groundwater arsenic in Chimaltenango, Guatemala.

PubMed

Lotter, Jason T; Lacey, Steven E; Lopez, Ramon; Socoy Set, Genaro; Khodadoust, Amid P; Erdal, Serap

2014-09-01

In the Municipality of Chimaltenango, Guatemala, we sampled groundwater for total inorganic arsenic. In total, 42 samples were collected from 27 (43.5%) of the 62 wells in the municipality, with sites chosen to achieve spatial representation throughout the municipality. Samples were collected from household faucets used for drinking water, and sent to the USA for analysis. The only site found to have a concentration above the 10 μg/L World Health Organization provisional guideline for arsenic in drinking water was Cerro Alto, where the average concentration was 47.5 μg/L. A health risk assessment based on the arsenic levels found in Cerro Alto showed an increase in noncarcinogenic and carcinogenic risks for residents as a result of consuming groundwater as their primary drinking water source. Using data from the US Geological Survey and our global positioning system data of the sample locations, we found Cerro Alto to be the only site sampled within the tertiary volcanic rock layer, a known source of naturally occurring arsenic. Recommendations were made to reduce the levels of arsenic found in the community's drinking water so that the health risks can be managed.

VizieR Online Data Catalog: Solar neighborhood. XXXII. L and M dwarfs (Dieterich+, 2014)

NASA Astrophysics Data System (ADS)

Dieterich, S. B.; Henry, T. J.; Jao, W.-C.; Winters, J. G.; Hosey, A. D.; Riedel, A. R.; Subasavage, J. P.

2015-01-01

We obtained VRI photometry for all targets in our sample using the Cerro Tololo Inter-American Observatory (CTIO) 0.9m telescope for the brighter targets and the SOuthern Astrophysical Research (SOAR) Optical Imager camera on the SOAR 4.1m telescope for fainter targets. SOAR observations were conducted between 2009 September and 2010 December during six observing runs comprising NOAO programs 2009B-0425, 2010A-0185, and 2010B-0176. A total of 17 nights on SOAR were used for optical photometry. Table 1 shows the photometry in the photometric system used by the telescope with which the measurements were taken (Johnson-Kron-Cousins for the CTIO 0.9m telescope and Bessell for SOAR). Astrometric observations are based in part on observations obtained via the Cerro Tololo Inter-American Observatory Parallax Investigation (CTIOPI), at the Cerro Tololo 0.9m telescope. CTIOPI is a large and versatile astrometric monitoring program targeting diverse types of stellar and substellar objects in the solar neighborhood. Observations are taken using the CTIO 0.9m telescope and its sole instrument, a 2048*2048 Tektronix imaging CCD detector with a plate scale of 0.401''/pixel. (4 data files).

Manipulating proteostasis to repair the F508del-CFTR defect in cystic fibrosis.

PubMed

Esposito, Speranza; Tosco, Antonella; Villella, Valeria R; Raia, Valeria; Kroemer, Guido; Maiuri, Luigi

2016-12-01

Cystic fibrosis (CF) is a lethal monogenic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that entails the (diagnostic) increase in sweat electrolyte concentrations, progressive lung disease with chronic inflammation and recurrent bacterial infections, pancreatic insufficiency, and male infertility. Therapies aimed at restoring the CFTR defect have emerged. Thus, a small molecule which facilitates chloride channel opening, the potentiator Ivacaftor, has been approved for the treatment of CF patients bearing a particular class of rare CFTR mutations. However, small molecules that directly target the most common misfolded CFTR mutant, F508del, and improve its intracellular trafficking in vitro, have been less effective than expected when tested in CF patients, even in combination with Ivacaftor. Thus, new strategies are required to circumvent the F508del-CFTR defect. Airway and intestinal epithelial cells from CF patients bearing the F508del-CFTR mutation exhibit an impressive derangement of cellular proteostasis, with oxidative stress, overactivation of the tissue transglutaminase (TG2), and disabled autophagy. Proteostasis regulators such as cysteamine can rescue and stabilize a functional F508del-CFTR protein through suppressing TG2 activation and restoring autophagy in vivo in F508del-CFTR homozygous mice, in vitro in CF patient-derived cell lines, ex vivo in freshly collected primary patient's nasal cells, as well as in a pilot clinical trial involving homozygous F508del-CFTR patients. Here, we discuss how the therapeutic normalization of defective proteostasis can be harnessed for the treatment of CF patients with the F508del-CFTR mutation.

Estudio multifrecuencia del medio interestelar cercano a HD 192281

NASA Astrophysics Data System (ADS)

Arnal, E. M.; Cappa, C.; Cichowolski, S.; Pineault, S.; St-Louis, N.

Una de las causas que modifica la estructura y dinámica del medio interestelar es la acción que los vientos de las estrellas de gran masa ejercen sobre el mismo. En este trabajo, mediante el uso de datos interferométricos obtenidos en la banda de radio en la transición de 21-cm del Hidrógeno neutro y de imágenes de la emisión de continuo en las bandas de 408 y 1420 MHz, de imágenes HIRES del satélite IRAS en 60 y 100 micrones, y de observaciones de continuo obtenidas con radiotelescopios de disco simple en 2695, 4850 y 8350 MHz se ha realizado un estudio multifrecuencia de los efectos que los vientos estelares de HD 192281, una estrella de tipo espectral O5 Vn((f))p, han tenido sobre el medio interestelar que rodea a la misma.

Estudio multifrecuencia del medio interestelar cercano a HD 192281

NASA Astrophysics Data System (ADS)

Arnal, E. M.; Cappa, C. E.; Cichowolski, S.; Pineault, S.; St-Louis, N.

Una de las causas que modifica la estructura y dinámica del medio interestelar es la acción que los vientos de las estrellas de gran masa ejercen sobre el mismo. En este trabajo, mediante el uso de datos interferométricos obtenidos en la banda de radio en la transición de λ˜21-cm del hidrógeno neutro y de imágenes de la emisión de continuo en las bandas de 408 y 1420 MHz, de imágenes HIRES del satélite IRAS en 60 y 100μm, y de observaciones de continuo obtenidas con radiotelescopios de disco simple en 2695, 4850 y 8350 MHz se ha realizado un estudio multifrecuencia de los efectos que los vientos estelares de HD 192281, una estrella de tipo espectral O5,Vn((f))p, han tenido sobre el medio interestelar que rodea a la misma.

The Marianas-San Marcos vein system: characteristics of a shallow low sulfidation epithermal Au-Ag deposit in the Cerro Negro district, Deseado Massif, Patagonia, Argentina

NASA Astrophysics Data System (ADS)

Vidal, Conrado Permuy; Guido, Diego M.; Jovic, Sebastián M.; Bodnar, Robert J.; Moncada, Daniel; Melgarejo, Joan Carles; Hames, Willis

2016-08-01

The Cerro Negro district, within the Argentinian Deseado Massif province, has become one of the most significant recent epithermal discoveries, with estimated reserves plus resources of ˜6.7 Moz Au equivalent. The Marianas-San Marcos vein system contains about 70 % of the Au-Ag resources in the district. Mineralization consists of Upper Jurassic (155 Ma) epithermal Au- and Ag-rich veins of low to intermediate sulfidation style, hosted in and genetically related to Jurassic intermediate composition volcanic rocks (159-156 Ma). Veins have a complex infill history, represented by ten stages with clear crosscutting relationships that can be summarized in four main episodes: a low volume, metal-rich initial episode (E1), an extended banded quartz episode with minor mineralization (E2), a barren waning stage episode (E3), and a silver-rich late tectonic-hydrothermal episode (E4). The first three episodes are interpreted to have formed at the same time and probably from fluids of similar composition: a 290-230 °C fluid dominated by meteoric and volcanic waters (-3‰ to -0‰ δ18Owater), with <3 % NaCl equivalent salinity and with a magmatic source of sulfur (-1 to -2 ‰ δ34Swater). Metal was mainly precipitated at the beginning of vein formation (episode 1) due to a combination of boiling at ˜600 to 800 m below the paleowater table, and associated mixing/cooling processes, as evidenced by sulfide-rich bands showing crustiform-colloform quartz, adularia, and chlorite-smectite banding. During episodes 2 and 3, metal contents progressively decrease during continuing boiling conditions, and veins were filled by quartz and calcite during waning stages of the hydrothermal system, and the influx of bicarbonate waters (-6 to -8.5 ‰ δ18Owater). Hydrothermal alteration is characterized by proximal illite, adularia, and silica zone with chlorite and minor epidote, intermediate interlayered illite-smectite and a distal chlorite halo. This assemblage is in agreement with

[La diagnosi del disturbo da uso di alcol dal punto di vista psicologico].

PubMed

Coriale, Giovanna; Fiorentino, Daniela; Porrari, Raffaella; Battagliese, Gemma; Capriglione, Ida; Cereatti, Federica; Iannuzzi, Silvia; Mauri, Benilde; Galli, Domenica; Fiore, Marco; Attilia, Maria Luisa; Ceccanti, Mauro

2018-01-01

RIASSUNTO. Il disturbo da uso di alcol (DUA) è uno dei disturbi psichiatrici più comuni nella popolazione generale. Il DUA è caratterizzato da un pattern di bere eccessivo, che si mantiene nonostante gli effetti negativi che l'alcol ha sul funzionamento lavorativo, sulla salute, sulle problematiche legali, sull'educazione e sulla vita sociale. Attualmente, il modello bio-psico-sociale è quello che spiega meglio il DUA. Infatti, molte ricerche hanno fornito evidenze su come il DUA sia una patologia multidimensionale. Variabili biologiche, psicologiche e socio-culturali entrano in gioco nell'eziologia, nella natura, nel mantenimento e nel cambiamento nel tempo del disturbo. La fase diagnostica è un momento importante del processo di cura, perché il successo del trattamento dipende in larga misura dall'esattezza e dall'adeguatezza della diagnosi. La diagnosi clinica si basa su una valutazione globale del funzionamento del paziente e utilizza il colloquio e gli strumenti psicometrici come mezzo di raccolta di informazioni. Questo articolo fornirà una panoramica delle dimensioni psicologiche più importanti da valutare e sui migliori strumenti psicometrici da usare per una diagnosi adeguata.

The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility*

PubMed Central

Mitzelfelt, Katie A.; Limphong, Pattraranee; Choi, Melinda J.; Kondrat, Frances D. L.; Lai, Shuping; Kolander, Kurt D.; Kwok, Wai-Meng; Dai, Qiang; Grzybowski, Michael N.; Zhang, Huali; Taylor, Graydon M.; Lui, Qiang; Thao, Mai T.; Hudson, Judith A.; Barresi, Rita; Bushby, Kate; Jungbluth, Heinz; Wraige, Elizabeth; Geurts, Aron M.; Benesch, Justin L. P.; Riedel, Michael; Christians, Elisabeth S.; Minella, Alex C.; Benjamin, Ivor J.

2016-01-01

Mutations of HSPB5 (also known as CRYAB or αB-crystallin), a bona fide heat shock protein and molecular chaperone encoded by the HSPB5 (crystallin, alpha B) gene, are linked to multisystem disorders featuring variable combinations of cataracts, cardiomyopathy, and skeletal myopathy. This study aimed to investigate the pathological mechanisms involved in an early-onset myofibrillar myopathy manifesting in a child harboring a homozygous recessive mutation in HSPB5, 343delT. To study HSPB5 343delT protein dynamics, we utilize model cell culture systems including induced pluripotent stem cells derived from the 343delT patient (343delT/343delT) along with isogenic, heterozygous, gene-corrected control cells (WT KI/343delT) and BHK21 cells, a cell line lacking endogenous HSPB5 expression. 343delT/343delT and WT KI/343delT-induced pluripotent stem cell-derived skeletal myotubes and cardiomyocytes did not express detectable levels of 343delT protein, contributable to the extreme insolubility of the mutant protein. Overexpression of HSPB5 343delT resulted in insoluble mutant protein aggregates and induction of a cellular stress response. Co-expression of 343delT with WT prevented visible aggregation of 343delT and improved its solubility. Additionally, in vitro refolding of 343delT in the presence of WT rescued its solubility. We demonstrate an interaction between WT and 343delT both in vitro and within cells. These data support a loss-of-function model for the myopathy observed in the patient because the insoluble mutant would be unavailable to perform normal functions of HSPB5, although additional gain-of-function effects of the mutant protein cannot be excluded. Additionally, our data highlight the solubilization of 343delT by WT, concordant with the recessive inheritance of the disease and absence of symptoms in carrier individuals. PMID:27226619

63. G.F.H., photographer July 30, 1932 DEL NORTE COUNTY, SECTION ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

63. G.F.H., photographer July 30, 1932 DEL NORTE COUNTY, SECTION A, HIGHWAY 1. 1-DN A #124, STA. 164=00 SHOWING DRAINAGE CONDITIONS, G.F.H., 7-30-32. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

Del(20q) in patients with chronic lymphocytic leukemia: A therapy-related abnormality involving lymphoid or myeloid cells

PubMed Central

Yin, C. Cameron; Tang, Guilin; Lu, Gary; Feng, Xiaoli; Keating, Michael J.; Medeiros, L. Jeffrey; Abruzzo, Lynne V.

2015-01-01

Del(20q), a common cytogenetic abnormality in myeloid neoplasms, is rare in chronic lymphocytic leukemia. We report 64 patients with chronic lymphocytic leukemia and del(20q), as the sole abnormality in 40, a stemline abnormality in 21, and a secondary abnormality in 3 cases. FISH analysis revealed an additional high-risk abnormality, del(11q) or del(17p), in 27/64 (42%) cases. In most cases, the leukemic cells showed atypical cytologic features, unmutated IGHV genes and ZAP70 positivity. The del(20q) was detected only after chemotherapy in all 27 cases with initial karyotypes available. With a median follow-up of 90 months, 30 patients (47%) died, most as a direct consequence of chronic lymphocytic leukemia. Eight patients developed a therapy-related myeloid neoplasm, seven with a complex karyotype. Combined morphologic and FISH analysis for del(20q) performed in 12 cases without morphologic evidence of a myeloid neoplasm localized the del(20q) to the chronic lymphocytic leukemia cells in 5 (42%) cases, and to myeloid/erythroid cells in 7 (58)% cases. The del(20q) was detected in myeloid cells in all 4 cases of myelodysplastic syndrome. In aggregate, these data indicate that chronic lymphocytic leukemia with del(20q) acquired after therapy is heterogeneous. In cases with morphologic evidence of dysplasia, the del(20q) likely resides in the myeloid lineage. However, in cases without morphologic evidence of dysplasia, the del(20q) may represent clonal evolution and disease progression. Combining morphologic analysis with FISH for del(20q) or performing FISH on immunomagnetically-selected subpopulations to localize the cell population with this abnormality may help guide patient management. PMID:25953391

Gene expression profiling assigns CHEK2 1100delC breast cancers to the luminal intrinsic subtypes.

PubMed

Nagel, Jord H A; Peeters, Justine K; Smid, Marcel; Sieuwerts, Anieta M; Wasielewski, Marijke; de Weerd, Vanja; Trapman-Jansen, Anita M A C; van den Ouweland, Ans; Brüggenwirth, Hennie; van I Jcken, Wilfred F J; Klijn, Jan G M; van der Spek, Peter J; Foekens, John A; Martens, John W M; Schutte, Mieke; Meijers-Heijboer, Hanne

2012-04-01

CHEK2 1100delC is a moderate-risk cancer susceptibility allele that confers a high breast cancer risk in a polygenic setting. Gene expression profiling of CHEK2 1100delC breast cancers may reveal clues to the nature of the polygenic CHEK2 model and its genes involved. Here, we report global gene expression profiles of a cohort of 155 familial breast cancers, including 26 CHEK2 1100delC mutant tumors. In line with previous work, all CHEK2 1100delC mutant tumors clustered among the hormone receptor-positive breast cancers. In the hormone receptor-positive subset, a 40-gene CHEK2 signature was subsequently defined that significantly associated with CHEK2 1100delC breast cancers. The identification of a CHEK2 gene signature implies an unexpected biological homogeneity among the CHEK2 1100delC breast cancers. In addition, all 26 CHEK2 1100delC tumors classified as luminal intrinsic subtype breast cancers, with 8 luminal A and 18 luminal B tumors. This biological make-up of CHEK2 1100delC breast cancers suggests that a relatively limited number of additional susceptibility alleles are involved in the polygenic CHEK2 model. Identification of these as-yet-unknown susceptibility alleles should be aided by clues from the 40-gene CHEK2 signature.

Volcanic deformation in the Andes

NASA Astrophysics Data System (ADS)

Riddick, S.; Fournier, T.; Pritchard, M.

2009-05-01

We present the results from an InSAR survey of volcanic activity in South America. We use data from the Japanese Space Agency's ALOS L-band radar satellite from 2006-2009. The L-band instrument provides better coherence in densely vegetated regions, compared to the shorter wave length C-band data. The survey reveals volcano related deformation in regions, north, central and southern, of the Andes volcanic arc. Since observations are limited to the austral summer, comprehensive coverage of all volcanoes is not possible. Yet, our combined observations reveal volcanic/hydrothermal deformation at Lonquimay, Llaima, Laguna del Maule, and Chaitén volcanoes, extend deformation measurements at Copahue, and illustrate temporal complexity to the previously described deformation at Cerro Hudson and Cordón Caulle. No precursory deformation is apparent before the large Chaitén eruption (VEI_5) of 2 May 2008, (at least before 16 April) suggesting rapid magma movement from depth at this long dormant volcano. Subsidence at Ticsani Volcano occurred coincident with an earthquake swarm in the same region.

Processing and thermodynamics research, Volume II. Monthly progress report, November 1984

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Data assembly is in progress on the Venezuelan Cerro Negro, California, Wilmington and Mexican Mayan crudes. A draft of a proposal is in preparation that might join this correlational work with complementary correlational work at the University of Oklahoma (Project BPT1). Cerro Negro 200 to 425/sup 0/C and 425 to 550/sup 0/C saturate fractions were analyzed with the CEC 21-103 mass spectrometer using ASTM method D2786, and experiments were devised to establish reproducibility of analyses with the KRATOS MS-50 (Project BPT2). Thermodynamic property measurements on organic nitrogen compounds included a liquid phase heat capacity study of 2,5-dimethylpyridine, and the oxygenmore » sensitivity of phenanthridine was checked prior to bomb calorimetry (Project BPT3A). Heat capacity measurements on chroman are progressing well, and vapor pressure measurements of tetrahydrophenanthrene are in progress (Project BPT3B). Work was begun on the design and procurement of equipment necessary for construction of a bench scale catalytic cracking unit. The supercritical extraction unit is being assembled (Project OPT1). Thiopene separations were begun on Cerro Negro 425 to 550/sup 0/C neutrals, and separation of sulfides from Cerro Negro 550 to 700/sup 0/C and 700+/sup 0/C neutrals was completed (Project OPT2). Preparations for PVT studies of methanol are nearing completion, and a list of critically needed PVT measurements was reviewed to help select the next compound for study. A possible candidate is hydrogen sulfide. (Project OPT3). Good progress continues in the treatment of the RP feed (Project OPT4) to recover Milspec F-76. It is anticipated that 85% recovery is possible by the chemical treatment/distillation process.« less

Eruptive Massive Vector Particles of 5-Dimensional Kerr-Gödel Spacetime

NASA Astrophysics Data System (ADS)

Övgün, A.; Sakalli, I.

2018-02-01

In this paper, we investigate Hawking radiation of massive spin-1 particles from 5-dimensional Kerr-Gödel spacetime. By applying the WKB approximation and the Hamilton-Jacobi ansatz to the relativistic Proca equation, we obtain the quantum tunneling rate of the massive vector particles. Using the obtained tunneling rate, we show how one impeccably computes the Hawking temperature of the 5-dimensional Kerr-Gödel spacetime.

Del(20q) in patients with chronic lymphocytic leukemia: a therapy-related abnormality involving lymphoid or myeloid cells.

PubMed

Yin, C Cameron; Tang, Guilin; Lu, Gary; Feng, Xiaoli; Keating, Michael J; Medeiros, L Jeffrey; Abruzzo, Lynne V

2015-08-01

Deletion 20q (Del(20q)), a common cytogenetic abnormality in myeloid neoplasms, is rare in chronic lymphocytic leukemia. We report 64 patients with chronic lymphocytic leukemia and del(20q), as the sole abnormality in 40, a stemline abnormality in 21, and a secondary abnormality in 3 cases. Fluorescence in situ hybridization (FISH) analysis revealed an additional high-risk abnormality, del(11q) or del(17p), in 25/64 (39%) cases. In most cases, the leukemic cells showed atypical cytologic features, unmutated IGHV (immunoglobulin heavy-chain variable region) genes, and ZAP70 positivity. The del(20q) was detected only after chemotherapy in all 27 cases with initial karyotypes available. With a median follow-up of 90 months, 30 patients (47%) died, most as a direct consequence of chronic lymphocytic leukemia. Eight patients developed a therapy-related myeloid neoplasm, seven with a complex karyotype. Combined morphologic and FISH analysis for del(20q) performed in 12 cases without morphologic evidence of a myeloid neoplasm localized the del(20q) to the chronic lymphocytic leukemia cells in 5 (42%) cases, and to myeloid/erythroid cells in 7 (58)% cases. The del(20q) was detected in myeloid cells in all 4 cases of myelodysplastic syndrome. In aggregate, these data indicate that chronic lymphocytic leukemia with del(20q) acquired after therapy is heterogeneous. In cases with morphologic evidence of dysplasia, the del(20q) likely resides in the myeloid lineage. However, in cases without morphologic evidence of dysplasia, the del(20q) may represent clonal evolution and disease progression. Combining morphologic analysis with FISH for del(20q) or performing FISH on immunomagnetically selected sub-populations to localize the cell population with this abnormality may help guide patient management.

62. R.L.T., photographer November 1, 1934 DEL NORTE COUNTY, SECTION ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

62. R.L.T., photographer November 1, 1934 DEL NORTE COUNTY, SECTION D, HIGHWAY 1. REDWOOD CLEARING ON EXISTING LINE, 1-DN-71-A #26, R.L.T. 11-1-34. Stamped office copy. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

60. C.J.T., photographer December 23, 1955 KLAMATH RIVER BRIDGE, DEL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

60. C.J.T., photographer December 23, 1955 KLAMATH RIVER BRIDGE, DEL NORTE COUNTY, SECTION A, HIGHWAY 1. DN-1-A #538, KLAMATH RIVER BR. FROM SO. END, 12/23/55, C.J.T. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

Fish and mammals in the economy of an ancient Peruvian kingdom

PubMed Central

Marcus, Joyce; Sommer, Jeffrey D.; Glew, Christopher P.

1999-01-01

Fish and mammal bones from the coastal site of Cerro Azul, Peru shed light on economic specialization just before the Inca conquest of A.D. 1470. The site devoted itself to procuring anchovies and sardines in quantity for shipment to agricultural communities. These small fish were dried, stored, and eventually transported inland via caravans of pack llamas. Cerro Azul itself did not raise llamas but obtained charqui (or dried meat) as well as occasional whole adult animals from the caravans. Guinea pigs were locally raised. Some 20 species of larger fish were caught by using nets; the more prestigious varieties of these show up mainly in residential compounds occupied by elite families. PMID:10339628

Digitalización de diapositivas del Sol en H α

NASA Astrophysics Data System (ADS)

Missio, H.; Montenegro, C.; Montenegro, R.

El objetivo de este trabajo ha sido el de obtener imágenes digitalizadas de las diapositivas tomadas del Sol en luz de hidrógeno de la línea correspondiente a Hα, y de esta manera llegar a convertir las mismas a un archivo digital para poder ser tratadas luego por computadora y poder contabilizar con exactitud, mediante un programa adecuado para tal fin, las zonas activas del Sol en la imagen digitalizada. En principio, para llegar a esto se pensó en la utilización de medios accesibles, y como detector se utilizó un fototransistor ubicado dentro de un soporte rectangular sobre dos ejes de desplazamiento X e Y. Se han obtenido con este procedimiento imágenes de buena calidad, construídas a partir de tres datos digitalizados en cada barrido que aportan la posición X e Y y la intensidad del pixel en ese punto indicada en 255 tonos de grises.

CHEK2 (∗) 1100delC Mutation and Risk of Prostate Cancer.

PubMed

Hale, Victoria; Weischer, Maren; Park, Jong Y

2014-01-01

Although the causes of prostate cancer are largely unknown, previous studies support the role of genetic factors in the development of prostate cancer. CHEK2 plays a critical role in DNA replication by responding to double-stranded breaks. In this review, we provide an overview of the current knowledge of the role of a genetic variant, 1100delC, of CHEK2 on prostate cancer risk and discuss the implication for potential translation of this knowledge into clinical practice. Currently, twelve articles that discussed CHEK2 (∗)1100delC and its association with prostate cancer were identified. Of the twelve prostate cancer studies, five studies had independent data to draw conclusive evidence from. The pooled results of OR and 95% CI were 1.98 (1.23-3.18) for unselected cases and 3.39 (1.78-6.47) for familial cases, indicating that CHEK2 (∗)1100delC mutation is associated with increased risk of prostate cancer. Screening for CHEK2(∗)1100delC should be considered in men with a familial history of prostate cancer.

CHEK2 ∗1100delC Mutation and Risk of Prostate Cancer

PubMed Central

Park, Jong Y.

2014-01-01

Although the causes of prostate cancer are largely unknown, previous studies support the role of genetic factors in the development of prostate cancer. CHEK2 plays a critical role in DNA replication by responding to double-stranded breaks. In this review, we provide an overview of the current knowledge of the role of a genetic variant, 1100delC, of CHEK2 on prostate cancer risk and discuss the implication for potential translation of this knowledge into clinical practice. Currently, twelve articles that discussed CHEK2 ∗1100delC and its association with prostate cancer were identified. Of the twelve prostate cancer studies, five studies had independent data to draw conclusive evidence from. The pooled results of OR and 95% CI were 1.98 (1.23–3.18) for unselected cases and 3.39 (1.78–6.47) for familial cases, indicating that CHEK2 ∗1100delC mutation is associated with increased risk of prostate cancer. Screening for CHEK2∗1100delC should be considered in men with a familial history of prostate cancer. PMID:25431674

The Cuernos del Paine mountains in Torres del Paine National Park in Chile, photographed during NASA's AirSAR 2004 campaign

NASA Image and Video Library

2004-03-11

The Cuernos del Paine mountains in Torres del Paine National Park in Chile, photographed during NASA's AirSAR 2004 campaign. AirSAR 2004 is a three-week expedition in Central and South America by an international team of scientists that is using an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR), located onboard NASA's DC-8 airborne laboratory. Scientists from many parts of the world are combining ground research with NASA's AirSAR technology to improve and expand on the quality of research they are able to conduct. Founded in 1959, Torres del Paine National Park encompasses 450,000 acres in the Patagonia region of Chile. This region is being studied by NASA using a DC-8 equipped with an Airborne Synthetic Aperture Radar (AirSAR) developed by scientists from NASA’s Jet Propulsion Laboratory. This is a very sensitive region that is important to scientists because the temperature has been consistently rising causing a subsequent melting of the region’s glaciers. AirSAR will provide a baseline model and unprecedented mapping of the region. This data will make it possible to determine whether the warming trend is slowing, continuing or accelerating. AirSAR will also provide reliable information on ice shelf thickness to measure the contribution of the glaciers to sea level.

The Turn of the Millennium, CTIO and AURA-O, 1993-2007

NASA Astrophysics Data System (ADS)

Smith, M. G.

2015-05-01

The decade 1993-2003 was a particularly exciting time to be at Cerro Tololo - for most staff members. Tough times at the beginning involved significant staff reductions - the worst moment of my professional career. In return, the observatory was granted a period of stability in which it was possible to rebuild morale, which in turn helped the research climate to recover rapidly. Emphasis was given to improving the image quality at the Blanco 4m (led by Jack Baldwin), while quietly supporting efficient operation of the smaller telescopes (led locally by Alistair Walker) via the development of the SMARTs consortium. In 1998 came the high point - the announcement of the discovery of Dark Energy that showed us all how much we still have to learn about the universe; this work depended crucially on the work of staff members at CTIO and staff and students from Chilean and Argentinian universities (as described elsewhere at this conference). The Inter-American nature of CTIO also laid the crucial groundwork (in which Joao Steiner was a key player) for Brazil's involvement in SOAR and Gemini. Work during the period to minimize the advance of light pollution over Cerro Tololo (and the rest of northern Chile) helped create a credible case for siting the LSST on Cerro Pachón.

El ``Aula del Cel'': astronomy approaching high school

NASA Astrophysics Data System (ADS)

Ortiz-Gil, A.; Gómez Collado, M.; Gallego Calvente, A. T.

The “Aula del Cel” is a project carried out by the Astronomical Obsevatory of the University of Valencia, Spain. It offers high-school teachers a tool for teaching Astronomy to 10 to 17 year-old students. Different programs, experiments, and audiovisual presentations have been prepared by a team formed both by professional astronomers and teachers, and are offered in a format chosen to suit each particular age and curriculum group. Special sessions have been designed for students with special needs (for example blind or autistic children) in close contact with the pedagogical teams responsible for their education. Nearly three thousand students have already visited the “Aula del Cel” over the first six months that it has been offered to the school community.

CHEK2*1100delC homozygosity in the Netherlands—prevalence and risk of breast and lung cancer

PubMed Central

Huijts, Petra EA; Hollestelle, Antoinette; Balliu, Brunilda; Houwing-Duistermaat, Jeanine J; Meijers, Caro M; Blom, Jannet C; Ozturk, Bahar; Krol-Warmerdam, Elly MM; Wijnen, Juul; Berns, Els MJJ; Martens, John WM; Seynaeve, Caroline; Kiemeney, Lambertus A; van der Heijden, Henricus F; Tollenaar, Rob AEM; Devilee, Peter; van Asperen, Christi J

2014-01-01

The 1100delC mutation in the CHEK2 gene has a carrier frequency of up to 1.5% in individuals from North-West Europe. Women heterozygous for 1100delC have an increased breast cancer risk (odds ratio 2.7). To explore the prevalence and clinical consequences of 1100delC homozygosity in the Netherlands, we genotyped a sporadic breast cancer hospital-based cohort, a group of non-BRCA1/2 breast cancer families, and breast tumors from a tumor tissue bank. Three 1100delC homozygous patients were found in the cohort of 1434 sporadic breast cancer patients, suggesting an increased breast cancer risk for 1100delC homozygotes (odds ratio 3.4, 95% confidence interval 0.4–32.6, P=0.3). Another 1100delC homozygote was found in 592 individuals from 108 non-BRCA1/2 breast cancer families, and two more were found after testing 1706 breast tumors and confirming homozygosity on their wild-type DNA. Follow-up data was available for five homozygous patients, and remarkably, three of them had developed contralateral breast cancer. A possible relationship between 1100delC and lung cancer risk was investigated in 457 unrelated lung cancer patients but could not be confirmed. Due to the small number of 1100delC homozygotes identified, the breast cancer risk estimate associated with this genotype had limited accuracy but is probably higher than the risk in heterozygous females. Screening for CHEK2 1100delC could be beneficial in countries with a relatively high allele frequency. PMID:23652375

Primer registro para Peru del genero Nielsonia Young, 1977 (Hemiptera: Cicadellidae: Cicadellinae: Cicadellini)

USDA-ARS?s Scientific Manuscript database

En este articulo se reporta por primera vez para el Peru una especies del genero Nielsonia Young, 1977, de material procedente del Departamento de Tumbes. El genero ha sido reportada anteriormente de Ecuador, como unico registro para Sudamerica, y America Central. El unico especimen hembra encontra...

Ectopsocidae (Psocodea: 'Psocoptera') from Valle del Cauca and NNP Gorgona, Colombia.

PubMed

Manchola, Oscar Fernando Saenz; Obando, Ranulfo González; Aldrete, Alfonso N García

2014-04-14

The results of a survey of the psocid family Ectopsocidae in Valle del Cauca and NNP Gorgona, are here presented. Fifteen species were identified, in the genera Ectopsocus (14 species), and Ectopsocopsis (one species); four of the Ectopsocus species are new to science and are here described and illustrated. The male of E. thorntoni García Aldrete is here described. Records of Ectopsocopsis cryptomeriae (Enderlein), Ectopsocus briggsi McLachlan, E. californicus Banks, E. columbianus Badonnel, E. maindroni Badonnel, E. meridionalis Ribaga, E. pilosus Badonnel, E. richardsi Pearman, E. titschacki Jentsch, and E. vilhenai Badonnel, are provided. Ten species were found only in Valle del Cauca, two species were found only in the NNP Gorgona, and three species were found at both sites. The specimens studied are deposited in the Entomological Museum, Universidad del Valle, Santiago de Cali, Colombia (MUSENUV).

Desgarros del epitelio pigmentario de la retina: factores de riesgo, mecanismo y control terapéutico.

PubMed

Clemens, Christoph R; Eter, Nicole

2017-07-11

Los desgarros del epitelio pigmentario de la retina (EPR) se asocian en la mayoría de los casos con los desprendimientos vascularizados del EPR debido a una degeneración macular asociada a la edad (DMAE), y normalmente implican una pérdida adversa de la agudeza visual. Estudios recientes indican que ha habido un aumento en la incidencia de desgarros del EPR desde la introducción de fármacos anti-factor de crecimiento del endotelio vascular (anti-VEGF) así como una asociación temporal entre el desgarro y la inyección intravítrea. Dado que el número de pacientes con DMAE y el número de inyecciones anti-VEGF va en aumento, tanto la dificultad de prevenir desgarros del EPR como el tratamiento tras la formación de los desgarros han adquirido una mayor relevancia. De forma paralela, la evolución de la imagenología de la retina ha contribuido de manera significativa a comprender mejor el desarrollo de los desgarros del EPR en los últimos años. Esta revisión resume los conocimientos que se poseen actualmente sobre el desarrollo, los factores pronósticos y las estrategias terapéuticas de los desgarros del EPR antes y después de que estos se formen. © 2017 S. Karger AG, Basel.

33 CFR 334.110 - Delaware Bay off Cape Henlopen, Del.; naval restricted area.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Del.; naval restricted area. 334.110 Section 334.110 Navigation and Navigable Waters CORPS OF....110 Delaware Bay off Cape Henlopen, Del.; naval restricted area. (a) The area. Beginning at a point on... regulations in this section shall be enforced by the Commandant, Fourth Naval District, and such agencies as...

Modeling landscapes and past vegetation patterns of New Mexico's Rio Del Oso Valley

Treesearch

Richard D. Periman

2005-01-01

Humans have interacted with the landscape and ecosystem of New Mexico's Rio del Oso Valley for thousands of years. Throughout the Holocene, various cultures have dramatically affected and altered the Rio del Oso. An interdisciplinary research approach, incorporating geomorphology, paleobotany, archaeology, and history, provides a broad range of methodologies and...

El bosque estatal del nuevo milenio antes y después del huracán Georges

Treesearch

A.E. Lugo; E. Román Nunci; M. Quinones; H. Marcano Vega; I. Vicéns

2005-01-01

We studied changes that occurred between 1997 and 2005 on a secondary wet subtropical urban forest in the University of Puerto Rico’s Botanical Garden (Bosque Estatal del Nuevo Milenio). Hurricane Georges passed south of the forest on November 21, 1998 with 127 km/h winds. The study consisted of identifying species in 40 plots of 254 m2 each, measuring the diameter at...

78 FR 57379 - Cancellation of Pesticides for Non-Payment of Year 2013 Registration Maintenance Fees

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

...- Desiccant 049547-00014 Antibacterial Festival All Purpose Cleaner 051624-20001 AQB-035 Algae Control 051978... Weed Defense 084195-00001 Iobio Bacteria, Slime and Algae Control 085340-00001 Cerro Flow Products...

Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3β-C/EBPβ pathway.

PubMed

Maekawa, Tomoki; Hosur, Kavita; Abe, Toshiharu; Kantarci, Alpdogan; Ziogas, Athanasios; Wang, Baomei; Van Dyke, Thomas E; Chavakis, Triantafyllos; Hajishengallis, George

2015-09-16

Del-1 is an endothelial cell-secreted anti-inflammatory protein. In humans and mice, Del-1 expression is inversely related to that of IL-17, which inhibits Del-1 through hitherto unidentified mechanism(s). Here we show that IL-17 downregulates human endothelial cell expression of Del-1 by targeting a critical transcription factor, C/EBPβ. Specifically, IL-17 causes GSK-3β-dependent phosphorylation of C/EBPβ, which is associated with diminished C/EBPβ binding to the Del-1 promoter and suppressed Del-1 expression. This inhibitory action of IL-17 can be reversed at the GSK-3β level by PI3K/Akt signalling induced by D-resolvins. The biological relevance of this regulatory network is confirmed in a mouse model of inflammatory periodontitis. Intriguingly, resolvin-D1 (RvD1) confers protection against IL-17-driven periodontal bone loss in a Del-1-dependent manner, indicating an RvD1-Del-1 axis against IL-17-induced pathological inflammation. The dissection of signalling pathways regulating Del-1 expression provides potential targets to treat inflammatory diseases associated with diminished Del-1 expression, such as periodontitis and multiple sclerosis.

An unexpected effect of TNF-α on F508del-CFTR maturation and function

PubMed Central

Bitam, Sara; Urbach, Valérie; Sermet-Gaudelus, Isabelle; Hinzpeter, Alexandre; Edelman, Aleksander

2015-01-01

Cystic fibrosis (CF) is a multifactorial disease caused by mutations in the cystic fibrosis transmembrane conductance regulator gene ( CFTR), which encodes a cAMP-dependent Cl - channel. The most frequent mutation, F508del, leads to the synthesis of a prematurely degraded, otherwise partially functional protein. CFTR is expressed in many epithelia, with major consequences in the airways of patients with CF, characterized by both fluid transport abnormalities and persistent inflammatory responses. The relationship between the acute phase of inflammation and the expression of wild type (WT) CFTR or F508del-CFTR is poorly understood. The aim of the present study was to investigate this effect. The results show that 10 min exposure to TNF-alpha (0.5-50ng/ml) of F508del-CFTR-transfected HeLa cells and human bronchial cells expressing F508del-CFTR in primary culture (HBE) leads to the maturation of F508del-CFTR and induces CFTR chloride currents. The enhanced CFTR expression and function upon TNFα is sustained, in HBE cells, for at least 24 h. The underlying mechanism of action involves a protein kinase C (PKC) signaling pathway, and occurs through insertion of vesicles containing F508del-CFTR to the plasma membrane, with TNFα behaving as a corrector molecule. In conclusion, a novel and unexpected action of TNFα has been discovered and points to the importance of systematic studies on the roles of inflammatory mediators in the maturation of abnormally folded proteins in general and in the context of CF in particular. PMID:26594334

Weyl fermions in a family of Gödel-type geometries with a topological defect

NASA Astrophysics Data System (ADS)

Garcia, G. Q.; Oliveira, J. R. De S.; Furtado, C.

In this paper, we study Weyl fermions in a family of Gödel-type geometries in Einstein general relativity. We also consider that these solutions are embedded in a topological defect background. We solve the Weyl equation and find the energy eigenvalues and eigenspinors for all three cases of Gödel-type geometries where a topological defect is passing through them. We show that the presence of a topological defect in these geometries contributes to the modification of the spectrum of energy. The energy zero modes for all three cases of the Gödel geometries are discussed.

General nonextremal rotating charged Gödel black holes in minimal five-dimensional gauged supergravity.

PubMed

Wu, Shuang-Qing

2008-03-28

I present the general exact solutions for nonextremal rotating charged black holes in the Gödel universe of five-dimensional minimal supergravity theory. They are uniquely characterized by four nontrivial parameters: namely, the mass m, the charge q, the Kerr equal rotation parameter a, and the Gödel parameter j. I calculate the conserved energy, angular momenta, and charge for the solutions and show that they completely satisfy the first law of black hole thermodynamics. I also study the symmetry and separability of the Hamilton-Jacobi and the massive Klein-Gordon equations in these Einstein-Maxwell-Chern-Simons-Gödel black hole backgrounds.

La implantacion del enfoque constructivista en el aula de ciencia: Estudio de caso multiple

NASA Astrophysics Data System (ADS)

Arroyo Betancourt, Luz I.

Esta investigacion estudia la implantacion del enfoque constructivista en tres aulas de ciencia del contexto puertorriqueno. Se auscultaron las practicas educativas que utilizan maestras consideradas constructivistas y la correspondencia de sus practicas educativas con los elementos esenciales de la didactica que proponen los teoricos de los planteamientos constructivistas. Se ausculto, ademas, a que vision del enfoque constructivista responden las expresiones de las maestras acerca de su practica educativa y como compara con su quehacer, a la luz de los elementos esenciales de las visiones constructivistas piagetiana, social y radical. Se utilizo el diseno de estudio descriptivo de caso multiple. El estudio se baso en entrevistas a profundidad, revision de documentos y observacion no participativa a la sala de clases. El contexto fueron tres escuelas publicas de la Region Educativa de San Juan, una elemental, una intermedia y una superior. Los resultados confirmaron que la transicion hacia el enfoque constructivista es un proceso que toma tiempo, dedicacion y la participacion en adiestramientos y readiestramientos acerca del nuevo enfoque. Las maestras coinciden en la mayoria de las practicas educativas que utilizan para implantar el enfoque constructivista de ensenanza y difieren en algunas debido, probablemente, a que han tenido que adaptarlas a los correspondientes niveles de ensenanza: elemental, intermedio y superior. Dos de las maestras planifican por conceptos generadores, mientras que una de ellas planifica siguiendo la guia que recibe del Departamento de Educacion. Difieren ademas, en el enfasis que confieren al inquirir cientifico. Con relacion a la correspondencia entre la vision manifestada por las maestras a la luz de las visiones piagetiana, social y radical, aparentemente, las preguntas del protocolo de entrevistas no lograron evocar la informacion con suficiente profundidad, por lo que la investigadora tuvo que inferir las visiones de las

Estimaciones de Prevalencia del VIH por Género y Grupo de Riesgo en Tijuana, México: 2006

PubMed Central

Iñiguez-Stevens, Esmeralda; Brouwer, Kimberly C.; Hogg, Robert S.; Patterson, Thomas L.; Lozada, Remedios; Magis-Rodriguez, Carlos; Elder, John P.; Viani, Rolando M.; Strathdee, Steffanie A.

2010-01-01

OBJETIVO Estimar la prevalencia del VIH en adultos de 15-49 años de edad en Tijuana, México - en la población general y en subgrupos de riesgo en el 2006. METODOS Se obtuvieron datos demográficos del censo Mexicano del 2005, y la prevalencia del VIH se obtuvo de la literatura. Se construyó un modelo de prevalencia del VIH para la población general y de acuerdo al género. El análisis de sensibilidad consistió en estimar errores estándar del promedio-ponderado de la prevalencia del VIH y tomar derivados parciales con respecto a cada parámetro. RESULTADOS La prevalencia del VIH es 0.54%(N = 4,347) (Rango: 0.22%–0.86%, (N = 1,750–6,944)). Esto sugiere que 0.85%(Rango: 0.39%–1.31%) de los hombres y 0.22%(Rango: 0.04%–0.40%) de las mujeres podrían ser VIH-positivos. Los hombres que tienen sexo con hombres (HSH), las trabajadoras sexuales usuarias de drogas inyectables (MTS-UDI), MTS-noUDI, mujeres UDI, y los hombres UDI contribuyeron las proporciones más elevadas de personas infectadas por el VIH. CONCLUSIONES El número de adultos VIH-positivos entre subgrupos de riesgo en la población de Tijuana es considerable, marcando la necesidad de enforcar las intervenciones de prevención en sus necesidades específicas. El presente modelo estima que hasta 1 en cada 116 adultos podrían ser VIH-positivos. PMID:19685824

An evening at "La Clinica del Pueblo".

PubMed

Shefsky, M L

1986-01-01

This article describes a typical evening at the Clinica del Pueblo in the Hispanic neighborhood of Adams-Morgan in Washington, D.c. The Clinical del Pueblo began operating in 1983 in response to the urgen medical needs of Central American refugees arriving in the Washington D.c. area. The refugees bring with them severe trauma, fear, and health problems caused by the civil was and exacerbated by inadequate or non-existant health services. Approximately 80,000 Salvadoran refugees live in the area. They do not receive adequate health care for 3 reasons. 1) Because the US goverment is unwilling to recognize them as true refugees, they live with the constant threat of deportatin back to the violence from which they have fled. 2) Refugees lack the ability to pay for private care. 3) Langauage and culture create frightening barriers to health care for the refugees. For those who do seek care, these barriers can lead to the inadequate or incomplete diagnoses and poor compliance and follow-up. Plenty International and the Central American Refugee Center responded to these problems by organizing a free clinic to provide not only medical care but also a training course for volunteers. The director of the clinic organizes the course, the classes are taught by a variety of people including the clinic's volunteer physicians, nurses, and public health educators as well as graduates of previus training courses and people from the wider community. The services of the clinic reach only a small portion of the population in need. However, the fact that free medical services are now available to some Central American refugees make the Clinica del Pueblo an important program.

The novel complex allele [A238V;F508del] of the CFTR gene: clinical phenotype and possible implications for cystic fibrosis etiological therapies.

PubMed

Diana, Anna; Polizzi, Angela Maria; Santostasi, Teresa; Ratclif, Luigi; Pantaleo, Maria Giuseppina; Leonetti, Giuseppina; Iusco, Danila Rosa; Gallo, Crescenzio; Conese, Massimo; Manca, Antonio

2016-06-01

Few mutations in cis have been annotated for F508del homozygous patients. Southern Italy patients who at a first analysis appeared homozygous for the F508del mutation (n=63) or compound heterozygous for the F508del and another mutation in the cystic fibrosis transmembrane conductance regulator gene (n=155) were searched for the A238V mutation in exon 6. The allelic frequency of the complex allele [A238V;F508del] was 0.04. When the whole data set was used (comprised also of 56 F508del/F508del and 34 F508del/other mutation controls), no differences reached the statistical significance in the clinical parameters, except chloride concentrations which were lower in [A238V;F508del]/other mutation compared with F508del/other mutation (P=0.03). The two study groups presented less complications than the control groups. Within the minimal data set (34 F508del/F508del, 27 F508del/other mutation, 4 [A238V;F508del]/F508del cases and 5 [A238V;F508del]/other mutation cases); that is, presenting all the variables in each patient, forced expiratory volume in 1 s and forced vital capacity presented a trend to lower levels in the study groups in comparison with the F508del/F508del group, and C-reactive protein approximated statistically significant higher levels in the [A238V;F508del]/other mutation as compared with F508del/F508del patients (P=0.09). The analysis of statistical dependence among the variables showed a significant anticorrelation between chloride and body mass index in the [A238V;F508del]/other mutation group. In conclusion, the complex allele [A238V;F508del] seems to be associated with less general complications than in the control groups, on the other hand possibly giving a worse pulmonary phenotype and higher systemic/local inflammatory response. These findings have implications for the correct recruitment and clinical response of F508del patients in the clinical trials testing the new etiological drugs for cystic fibrosis.

Comportamiento del Helio en estrellas químicamente peculiares

NASA Astrophysics Data System (ADS)

Malaroda, S. M.; López García, Z.; Leone, F.; Catalano, F.

Las estrellas químicamente peculiares (CP) se caracterizan por tener deficiencias y sobreabundancias de algunos elementos químicos de hasta 106 veces la abundancia solar. Además presentan variaciones en las líneas espectrales. Se piensa que ello se debe a que los campos magnéticos presentes en este tipo de estrellas son principalmente dipolares, con un eje de simetría diferente del eje de rotación. La distribución de los elementos sobreabundantes y deficientes no es homogénea sobre la superficie estelar y las variaciones observadas serían una consecuencia directa de la rotación estelar. Entre los elementos con abundancia anómala se encuentra el Helio, cuyas líneas tienen intensidades que no son consistentes con una abundancia normal, que no puede ser determinada del modo usual, o sea, considerando una atmósfera con composición solar. Con el fin de determinar la abundancia de este elemento, se inició un estudio de estrellas anómalas de Helio, Hew y He strong. Además se determinarán las abundancias de otros elementos anómalos como ser el Si, Cr, Mg, Mn y Fe. Las mismas se determinan del modo tradicional, o sea: a) medida de los anchos equivalentes de las líneas de los distintos elementos analizados; b) adopción de la temperatura efectiva, gravedad y abundancia del Helio; c) cálculo del modelo de atmósfera d) comparación con las observaciones y reinicio de un proceso iterativo hasta lograr un acuerdo entre todos los parámetros analizados. Las observaciones se llevaron a cabo en el Complejo Astronómico El Leoncito. Se observaron setenta y ocho estrellas anómalas de Helio. En este momento se está procediendo a calcular las abundancias correspondientes a los distintos elementos químicos. Para ello se hace uso de los modelos de Kurucz, ATLAS9. Los cálculos NLTE de las líneas de Helio se llevan a cabo con el programa MULTI y se compararán con los realizados con el programa WIDTH9 de Kurucz (LTE), con el objeto de resaltar la importancia de

Misura de Massa e Larghezza degli Stati $$x_1$$ e $$x_2$$ del Charmonio Formati in Interazioni $$p - \\bar{p}$$

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pallavicini, Marco

1995-01-01

Oggetto di questa tesi è la misura di alcune caratteristiche fisiche ( massa, larghezza, e larghezza parziale in p - p) degli stati 3 Pi e 3 A del charmonio, - overo del sistema legato di un quark "charm" e del suo antiquark-, nell'ambito dell'esperimento E-760, installato nell'accumulatore di antiprotoni del Fermilab (U.S.A).

Archivo de placas astrométricas del Observatorio de La Plata

NASA Astrophysics Data System (ADS)

di Sisto, R.; Orellana, R. B.

Se ha realizado una base de datos con las placas fotográficas obtenidas con el Astrográfico del Observatorio de La Plata. Se han clasificado un total de 3000 placas obtenidas para asteroides y cometas. El acceso a la base de datos se hará por FTP y la misma contendrá la siguiente información: fecha y tiempo de exposición, coordenadas del centro de placa, tipo de emulsión fotográfica, estado de la placa, objeto fotografiado.

Gonadal dysgenesis, Turner syndrome with 46,XX,del(18p)3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Telvi, L.; Ion, R.; Bernheim, A.

1994-09-01

The authors report a case of a female infant with gonadal dysgenesis, clinical features of Turner syndrome and a de novo del(18p). The factors controlling gonadal dysgenesis and Turner syndrome are unknown to date. The genes involved could be located not only on X chromosome but also on autosomes. The present case suggests that one of these genes is situated on the short arm of chromosome 18. We conclude that patients with del(18p) syndrome should be evaluated for gonadal dysgenesis.

Mejoras en el apuntado del telescopio de 2,15 mts de CASLEO

NASA Astrophysics Data System (ADS)

Aballay, J. L.; Casagrande, A. R.; Pereyra, P. F.; Marún, A. H.

Con el objeto de optimizar el funcionamiento del telescopio de 2,15 mts. de CASLEO, se están eliminando los motores de calar, de guía y mecánica asociada. Para ésto, se están diseñando dos electrónicas que gobernarán, solamente, el motor de slew y el de tracking. Con el control del motor de slew se realizarán las funciones de slew y calar, controlando desde una PC la placa que maneja las rampas de velocidad. De este modo, el movimiento será programado y por lo tanto, más suave y preciso. Con el control del motor de tracking, a través de un generador de frecuencias programable desde una PC, se proveerá los movimientos necesarios para el tracking y guía.

[Recommendations to improve the scientific communication process in the Revista Médica del IMSS].

PubMed

Álvarez, Ivón

2016-01-01

In order to improve the position of the Revista Médica del Instituto Mexicano del Seguro Social among the different journals, in this editorial we enumerate a series of recommendations to ameliorate the practices of the different actors who participate in the scientific communication process of this journal.

Detailed chronology of a giant Pleistocene rock-avalanche sequence in the hyperarid southern Peru revealed by jointly applied 10Be and 3He cosmic ray exposure dating : The Study case of the Cerro Caquilluco landslide complex.

NASA Astrophysics Data System (ADS)

Swann, Zerathe; Laurence, Audin; Carlos, Benavente; Régis, Braucher; Pierre-Henri, Blard; Didier, Bourlès; Julien, Carcaillet; Fabrizio, Delgado; Pascal, Lacroix; Valderrama Patricio, Murillo; Aster Team

2015-04-01

Giant landslides are recognized to be remarkably abundant on the Western Andean front of southern Peru and northern Chile, especially in the Arica Bend region (e.g. Crosta et al., 2014a). This area is characterized by strong topographic gradients and subsequent incision of deep canyons, due to the evolution of the Andean range that provide suitable conditions for the development of such instabilities. The climate is hyper-arid (Atacama Desert), although rare but highly impulsive wet events have been evidenced since the Pleistocene. In parallel, this region is submitted to strong (Mw 8-9) and recurrent (~100 yrs) subduction earthquakes. Previous studies suggest that large landslides represent the main agent of erosion of the Western Cordillera, providing soft material for subsequent fluvial remobilization. However the lack of time constrains on the numerous fossil landslides identified away from major canyons still hamper to assess a real mass balance of sliding material versus the known fluvial erosion and tectonic uplift rates. Finally the role of landslides in the long-term erosion rates of the Andean range on its arid flank remains quantitatively unknown. Recently, two studies gave divergent opinions about the main factor supposed to control the slope failures in that region. Based on cosmogenic nuclides derived erosion rates, McPhillips et al. (2014) argue that the last Holocene climate variation did not have had any effect on the rate of landsliding, suggesting that here landslides are mainly triggered by earthquake. On the other hand, Margirier et al. (2014) have showed a temporal correlation between a failure episode of the giant Chuquibamba landslide and the Ouki wet climatic event identified on the Altiplano ~100 ka ago. In this study we focus on dating the Cerro Caquilluco rock avalanche complex described by Crosta et al. (2014). With a total volume of about 15 km3, a length of 43 km and an internal structure characterized by various depositional lobes

Field Measurements of Respiratory Del13CO2 and Photodegradation

NASA Astrophysics Data System (ADS)

van Asperen, H.; Sabbatini, S.; Nicolini, G.; Warneke, T.; Papale, D.; Notholt, J.

2014-12-01

Carbon decomposition dynamics have been studied in a variety of ecosystems and its variation can mostly be explained in terms of environmental variables (e.g. temperature and precipitation). However, carbon dynamics in arid, water limited regions have shown to be very different and are still largely unknown. Several studies have indicated the importance of photodegradation, the direct breakdown of organic matter by sunlight, in these arid regions. A FTIR (Fourier Transform Infrared Spectrometer) was set up to continuously measure concentrations of CO2, CH4, N2O, CO as well as del13C in CO2. The FTIR was connected to 2 different flux measurement systems: a Flux Gradient system and 2 flux chambers, providing a continuous data set of gas concentrations and biosphere-atmosphere gas fluxes at different heights and scales. Field measurements showed photodegradation induced carbon fluxes. Also, respiratory del13CO2 was determined by use of Keeling plots, and was determined to vary between -25‰ and -21‰. A clear diurnal pattern in respiratory del13CO2 was found, suggesting either different (dominant) respiratory processes between day and night or the effect of diffusive fractionation.

Intermittency of gravity wave momentum flux in the mesopause region observed with an all-sky airglow imager

NASA Astrophysics Data System (ADS)

Cao, Bing; Liu, Alan Z.

2016-01-01

The intermittency of gravity wave momentum flux (MF) near the OH airglow layer (˜87 km) in the mesopause region is investigated for the first time using observation of all-sky airglow imager over Maui, Hawaii (20.7°N, 156.3°W), and Cerro Pachón, Chile (30.3°S, 70.7°W). At both sites, the probability density function (pdf) of gravity wave MF shows two distinct distributions depending on the magnitude of the MF. For MF smaller (larger) than ˜16 m2 s-2 (0.091 mPa), the pdf follows a lognormal (power law) distribution. The intermittency represented by the Bernoulli proxy and the percentile ratio shows that gravity waves have higher intermittency at Maui than at Cerro Pachón, suggesting more intermittent background variation above Maui. It is found that most of the MF is contributed by waves that occur very infrequently. But waves that individually contribute little MF are also important because of their higher occurrence frequencies. The peak contribution is from waves with MF around ˜2.2 m2 s-2 at Cerro Pachón and ˜5.5 m2 s-2 at Maui. Seasonal variations of the pdf and intermittency imply that the background atmosphere has larger influence on the observed intermittency in the mesopause region.

Ecos del Cosmos: A radio astroexperience at the Universitat de Valencia

NASA Astrophysics Data System (ADS)

Marco, E.; Ballesteros, F. J.; Ortiz-Gil, A.

2017-03-01

During the last three years Ecos del Cosmos has been a radio program dedicated to spreading astronomical hot news to the Universitat de València community and beyond, and also topics of general astronomical interest. To do this, this program by Ràdio Universitat has conducted live interviews with researchers, explored relationships of astronomy with humanities and society, performed contests and explained in a simple way the main monthly ephemerides. A version of Ecos del Cosmos was broadcasted in the Onda Cero’s summer program ''Jelo en verano''conducted by Arturo Tellez.

Pier Diego Siccardi (1880-1917) and the "Clinica del Lavoro" in the trench warfare.

PubMed

Riva, Michele Augusto; Caramella, Michela; Turato, Massimo; Cesana, Giancarlo

2017-12-14

The year 2017 marks the centenary of the death of the Italian scientist Pier Diego Siccardi (1880-1917), one of Luigi Devoto's assistants at the "Clinica del Lavoro" in Milan. To commemorate Siccardi and to describe the activities of the physicians of the "Clinica del Lavoro" during World War I. A comprehensive analysis was conducted on scientific papers written by Pier Diego Siccardi and by other physicians belonging to the Clinica del Lavoro, in the period 1915-1918. During the Great War, the Clinica del Lavoro became a military hospital, even though it indirectly maintained a role in Occupational Health, assisting women who had started to work to replace the men sent to the front. Devoto and his assistants were drafted as Army doctors, but continued their research activities while at the front; focusing on the diseases that affected the soldiers, mainly infections. Bleeding fevers and jaundice were endemic among Italian troops, but their etiology was unknown. Pier Diego Siccardi identified this syndrome as an infection caused by a spirochete, and was the first one to isolate the infectious agent. Siccardi prematurely died of the same disease as a consequence of a laboratory accident, which provided further confirmation for his research. The heroic life of Siccardi and his tragic death testify the important activities of the scientists of the "Clinica del Lavoro" in the years of the Great War.

DelPhiPKa web server: predicting pKa of proteins, RNAs and DNAs.

PubMed

Wang, Lin; Zhang, Min; Alexov, Emil

2016-02-15

A new pKa prediction web server is released, which implements DelPhi Gaussian dielectric function to calculate electrostatic potentials generated by charges of biomolecules. Topology parameters are extended to include atomic information of nucleotides of RNA and DNA, which extends the capability of pKa calculations beyond proteins. The web server allows the end-user to protonate the biomolecule at particular pH based on calculated pKa values and provides the downloadable file in PQR format. Several tests are performed to benchmark the accuracy and speed of the protocol. The web server follows a client-server architecture built on PHP and HTML and utilizes DelPhiPKa program. The computation is performed on the Palmetto supercomputer cluster and results/download links are given back to the end-user via http protocol. The web server takes advantage of MPI parallel implementation in DelPhiPKa and can run a single job on up to 24 CPUs. The DelPhiPKa web server is available at http://compbio.clemson.edu/pka_webserver. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

75 FR 25291 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-07

... Madison County Warden's Residence, 151 Stone St, Triana, 10000258 COLORADO Adams County Eastlake Farers Co..., Elizabeth R., House, 123 Edgehill Rd, New Haven, 10000260 IOWA Cerro Gordo County Surf Ballroom, 460 N Shore...

44 CFR 295.21 - Allowable compensation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... measures that will reduce the property's vulnerability to the future risk of wildfire, flood or other... wildfire, flood or other natural disaster resulting from the Cerro Grande Fire that are consistent with a...

44 CFR 295.21 - Allowable compensation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... measures that will reduce the property's vulnerability to the future risk of wildfire, flood or other... wildfire, flood or other natural disaster resulting from the Cerro Grande Fire that are consistent with a...

44 CFR 295.21 - Allowable compensation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... measures that will reduce the property's vulnerability to the future risk of wildfire, flood or other... wildfire, flood or other natural disaster resulting from the Cerro Grande Fire that are consistent with a...

44 CFR 295.21 - Allowable compensation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... measures that will reduce the property's vulnerability to the future risk of wildfire, flood or other... wildfire, flood or other natural disaster resulting from the Cerro Grande Fire that are consistent with a...

Meta-analysis of CHEK2 1100delC variant and colorectal cancer susceptibility.

PubMed

Xiang, He-ping; Geng, Xiao-ping; Ge, Wei-wei; Li, He

2011-11-01

Cell cycle checkpoint kinase 2 (CHEK2) gene has been inconsistently associated with colorectal cancer (CRC), particularly the 1100delC variant. To generate large-scale evidence on whether the CHEK2 1100delC variant is associated with CRC susceptibility we have conducted a meta-analysis. Data were collected from the following electronic databases: PubMed, Excerpta Medica Database and Chinese Biomedical Literature Database, with the last report up to November 2010. The odds ratio (OR) and its 95% confidence interval (95% CI) were used to assess the strength of association. We evaluated the contrast of carriers versus non-carriers. Meta-analysis was performed in a fixed/random effect model by using the software Review Manager 4.2. A total of six studies including 4194 cases and 10,010 controls based on the search criteria were involved in this meta-analysis. A significant association of the CHEK2 1100delC variant with unselected CRC was found (OR=2.11, 95% CI=1.41-3.16, P=0.0003). We also found an association of the CHEK2 1100delC variant with familial CRC (OR=2.80, 95% CI=1.74-4.51, P<0.0001). However, the association was not established for sporadic CRC (OR=1.45, 95% CI=0.49-4.30, P=0.50). This meta-analysis demonstrates that the CHEK2 1100delC variant may be an important CRC-predisposing gene, which increases CRC risk. Copyright © 2011. Published by Elsevier Ltd.

DelPhiForce web server: electrostatic forces and energy calculations and visualization.

PubMed

Li, Lin; Jia, Zhe; Peng, Yunhui; Chakravorty, Arghya; Sun, Lexuan; Alexov, Emil

2017-11-15

Electrostatic force is an essential component of the total force acting between atoms and macromolecules. Therefore, accurate calculations of electrostatic forces are crucial for revealing the mechanisms of many biological processes. We developed a DelPhiForce web server to calculate and visualize the electrostatic forces at molecular level. DelPhiForce web server enables modeling of electrostatic forces on individual atoms, residues, domains and molecules, and generates an output that can be visualized by VMD software. Here we demonstrate the usage of the server for various biological problems including protein-cofactor, domain-domain, protein-protein, protein-DNA and protein-RNA interactions. The DelPhiForce web server is available at: http://compbio.clemson.edu/delphi-force. delphi@clemson.edu. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

DelPhi web server v2: incorporating atomic-style geometrical figures into the computational protocol.

PubMed

Smith, Nicholas; Witham, Shawn; Sarkar, Subhra; Zhang, Jie; Li, Lin; Li, Chuan; Alexov, Emil

2012-06-15

A new edition of the DelPhi web server, DelPhi web server v2, is released to include atomic presentation of geometrical figures. These geometrical objects can be used to model nano-size objects together with real biological macromolecules. The position and size of the object can be manipulated by the user in real time until desired results are achieved. The server fixes structural defects, adds hydrogen atoms and calculates electrostatic energies and the corresponding electrostatic potential and ionic distributions. The web server follows a client-server architecture built on PHP and HTML and utilizes DelPhi software. The computation is carried out on supercomputer cluster and results are given back to the user via http protocol, including the ability to visualize the structure and corresponding electrostatic potential via Jmol implementation. The DelPhi web server is available from http://compbio.clemson.edu/delphi_webserver.

Los plaguicidas y la contaminacion del medio ambiente Venezolano

USGS Publications Warehouse

Stickel, L.F.; Stickel, W.H.

1972-01-01

RESUMEN DE RECOMENDACIONES Recomendaciones para el Programa de Investigacion: 1. Establecer un sistema de muestreo biologico para detectar los niveles tendencias de los productos quimicos toxicos en un peque?o numero de si tios representativos. 2. Mantener continua vigilancia de la contaminacion ambiental, mediante la seleccion acertadamente dirigida de las zonas afectadas y de las fuentes de contaminacion. 3. Realizar estudios acerca de las poblaciones de animales silvestres, y del exito de los procesos reproductivos de las especies o grupos clayes de animales que se consideran mas gravemente afectados. 4. Preparar recomendaciones para una accion gubernamental de proteccion al hombre, a la fauna silvestre y al medio ambiente. Recomendaciones para la Accion Administrativa: 1. Establecer limites a la tolerancia de los residuos de plaguicidas en los alimentos. Constituye una medida clave para disminuir la contaminacion ambiental. 2. Establecer normas de calidad del agua para las corrientes, represas, la gos y otros cuerpos. Es la segunda medida clave para reducir la contaminacion del ambiente 3. Exigir un tratamiento adecuado de los efluentes industriales, especialmente antes de que se construyan las nuevas plantas. 4. Exigir a los agricultores que en el uso de plaguicidas sigan los consejos tecnicos autorizados y negar a los vendedores el derecho a recomendar productos por su cuenta. 5. Tomar medidas para recoger y eliminar los recipientes y sobrantes de los plaguicidas.

Pluto's Atmosphere from the July 2010 Stellar Occultation

NASA Astrophysics Data System (ADS)

Person, Michael J.; Elliot, J. L.; Bosh, A. S.; Gulbis, A. A. S.; Jensen-Clem, R.; Lockhart, M. F.; Zangari, A. M.; Zuluaga, C. A.; Levine, S. E.; Pasachoff, J. M.; Souza, S. P.; Lu, M.; Malamut, C.; Rojo, P.; Bailyn, C. D.; MacDonald, R. K. D.; Ivarsen, K. M.; Reichart, D. E.; LaCluyze, A. P.; Nysewander, M. C.; Haislip, J. B.

2010-10-01

We have observed the 4 July 2010 stellar occultation by Pluto as part of our program of monitoring Pluto's atmospheric changes over the last decade. Successful observations were obtained from three sites: Cerro Calan and Cerro Tololo, Chile, as well as the HESS-project site (High Energy Stereoscopic System) in southwestern Namibia. Successful telescope apertures ranged from 0.45 m to 1.0 m and resulted in seven occultation light curves for the event from among the three sites. Simultaneous analysis of the seven light curves indicates that Pluto's atmosphere continues to be stable, as the calculated atmospheric radii are consistent with those detected in 2006 (Elliot et al., AJ 134, 1, 2007) and 2007 (Person et al., AJ 136, 1510, 2008), continuing the stability that followed the large pressure increase detected between 1988 (Millis et al., Icarus 105, 282, 1993) and 2002 (Elliot et al., Nature 424, 165, 2003). We will present the overall astrometric solution as well as current profiles for Pluto's upper atmospheric temperature and pressure obtained from inversion of the light curves (Elliot, Person, and Qu, AJ 126, 1041, 2003). This work was supported, in part, by grants NNX10AB27G to MIT, NNX08AO50G to Williams College, and NNH08AI17I to the USNO from NASA's Planetary Astronomy Division. The 0.75-m ATOM (Automatic Telescope for Optical Monitoring) light curve was obtained with the generous assistance of the HESS-project staff, arranged by Stefan Wagner and Marcus Hauser of the University of Heidelberg. The 0.45-m Goto telescope at Cerro Calán National Astronomical Observatory, Universidad de Chile, was donated by the Government of Japan. PROMPT (Panchromatic Robotic Optical Monitoring and Polarimetry Telescopes) observations at Cerro Tololo were made possible by the Robert Martin Ayers Science Fund. Student participation was supported in part by NSF's REU program and NASA's Massachusetts Space Grant.

CHEK2 c.1100delC allele is rarely identified in Greek breast cancer cases.

PubMed

Apostolou, Paraskevi; Fostira, Florentia; Papamentzelopoulou, Myrto; Michelli, Maria; Panopoulos, Christos; Fountzilas, George; Konstantopoulou, Irene; Voutsinas, Gerassimos E; Yannoukakos, Drakoulis

2015-04-01

The CHEK2 gene encodes a protein kinase that plays a crucial role in maintenance of genomic integrity and the DNA repair mechanism. CHEK2 germline mutations are associated with increased risk of breast cancer and other malignancies. From a clinical perspective, the most significant mutation identified is the c.1100delC mutation, which is associated with an approximately 25% lifetime breast cancer risk. The distribution of this mutation shows wide geographical variation; it is more prevalent in the Northern European countries and less common, or even absent, in Southern Europe. In order to estimate the frequency of the CHEK2 c.1100delC mutation in Greek breast cancer patients, we genotyped 2,449 patients (2,408 females and 41 males), which was the largest series ever tested for c.1100delC. The mean age of female and male breast cancer diagnosis was 49 and 59 years, respectively. All patients had previously tested negative for the Greek BRCA1 founder and recurrent mutations. The CHEK2 c.1100delC mutation was detected in 0.16% (4 of 2,408) of females, all of whom were diagnosed with breast cancer before the age of 50 years. Only one c.1100delC carrier was reported with breast cancer family history. The present study indicates that the CHEK2 c.1100delC mutation does not contribute substantially to hereditary breast cancer in patients of Greek descent. Copyright © 2015 Elsevier Inc. All rights reserved.

Haplotype analysis of the 185delAG BRCA1 mutation in ethnically diverse populations

PubMed Central

Laitman, Yael; Feng, Bing-Jian; Zamir, Itay M; Weitzel, Jeffrey N; Duncan, Paul; Port, Danielle; Thirthagiri, Eswary; Teo, Soo-Hwang; Evans, Gareth; Latif, Ayse; Newman, William G; Gershoni-Baruch, Ruth; Zidan, Jamal; Shimon-Paluch, Shani; Goldgar, David; Friedman, Eitan

2013-01-01

The 185delAG* BRCA1 mutation is encountered primarily in Jewish Ashkenazi and Iraqi individuals, and sporadically in non-Jews. Previous studies estimated that this is a founder mutation in Jewish mutation carriers that arose before the dispersion of Jews in the Diaspora ∼2500 years ago. The aim of this study was to assess the haplotype in ethnically diverse 185delAG* BRCA1 mutation carriers, and to estimate the age at which the mutation arose. Ethnically diverse Jewish and non-Jewish 185delAG*BRCA1 mutation carriers and their relatives were genotyped using 15 microsatellite markers and three SNPs spanning 12.5 MB, encompassing the BRCA1 gene locus. Estimation of mutation age was based on a subset of 11 markers spanning a region of ∼5 MB, using a previously developed algorithm applying the maximum likelihood method. Overall, 188 participants (154 carriers and 34 noncarriers) from 115 families were included: Ashkenazi, Iraq, Kuchin-Indians, Syria, Turkey, Iran, Tunisia, Bulgaria, non-Jewish English, non-Jewish Malaysian, and Hispanics. Haplotype analysis indicated that the 185delAG mutation arose 750–1500 years ago. In Ashkenazim, it is a founder mutation that arose 61 generations ago, and with a small group of founder mutations was introduced into the Hispanic population (conversos) ∼650 years ago, and into the Iraqi–Jewish community ∼450 years ago. The 185delAG mutation in the non-Jewish populations in Malaysia and the UK arose at least twice independently. We conclude that the 185delAG* BRCA1 mutation resides on a common haplotype among Ashkenazi Jews, and arose about 61 generations ago and arose independently at least twice in non-Jews. PMID:22763381

Detecting a hierarchical genetic population structure via Multi-InDel markers on the X chromosome

PubMed Central

Fan, Guang Yao; Ye, Yi; Hou, Yi Ping

2016-01-01

Detecting population structure and estimating individual biogeographical ancestry are very important in population genetics studies, biomedical research and forensics. Single-nucleotide polymorphism (SNP) has long been considered to be a primary ancestry-informative marker (AIM), but it is constrained by complex and time-consuming genotyping protocols. Following up on our previous study, we propose that a multi-insertion-deletion polymorphism (Multi-InDel) with multiple haplotypes can be useful in ancestry inference and hierarchical genetic population structures. A validation study for the X chromosome Multi-InDel marker (X-Multi-InDel) as a novel AIM was conducted. Genetic polymorphisms and genetic distances among three Chinese populations and 14 worldwide populations obtained from the 1000 Genomes database were analyzed. A Bayesian clustering method (STRUCTURE) was used to discern the continental origins of Europe, East Asia, and Africa. A minimal panel of ten X-Multi-InDels was verified to be sufficient to distinguish human ancestries from three major continental regions with nearly the same efficiency of the earlier panel with 21 insertion-deletion AIMs. Along with the development of more X-Multi-InDels, an approach using this novel marker has the potential for broad applicability as a cost-effective tool toward more accurate determinations of individual biogeographical ancestry and population stratification. PMID:27535707

Geothermal well drilling manual at Cerro Prieto

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fernandez P., A.; Flores S., M.

The objective of the drilling manual is to solve all problems directly related to drilling during the construction of a well. In this case, the topics dealt which are drilling fluids and hydraulics to be applied in the field to improve drilling progress, eliminate risks and achieve good well-completion. There are other topics that are applicable such as drill bits and the drilling string, which are closely linked to drilling progress. On this occasion drilling fluid and hydraulics programs are presented, in addition to a computing program for a Casio FX-502P calculator to be applied in the field to optimizemore » hydraulics and in the analysis of hydraulics for development and exploration wells at their different intervals.« less

Shear wave splitting and shear wave splitting tomography of the southern Puna plateau

NASA Astrophysics Data System (ADS)

Calixto, Frank J.; Robinson, Danielle; Sandvol, Eric; Kay, Suzanne; Abt, David; Fischer, Karen; Heit, Ben; Yuan, Xiaohui; Comte, Diana; Alvarado, Patricia

2014-11-01

We have investigated the seismic anisotropy beneath the Central Andean southern Puna plateau by applying shear wave splitting analysis and shear wave splitting tomography to local S waves and teleseismic SKS, SKKS and PKS phases. Overall, a very complex pattern of fast directions throughout the southern Puna plateau region and a circular pattern of fast directions around the region of the giant Cerro Galan ignimbrite complex are observed. In general, teleseismic lag times are much greater than those for local events which are interpreted to reflect a significant amount of sub and inner slab anisotropy. The complex pattern observed from shear wave splitting analysis alone is the result of a complex 3-D anisotropic structure under the southern Puna plateau. Our application of shear wave splitting tomography provides a 3-D model of anisotropy in the southern Puna plateau that shows different patterns depending on the driving mechanism of upper-mantle flow and seismic anisotropy. The trench parallel a-axes in the continental lithosphere above the slab east of 68W may be related to deformation of the overriding continental lithosphere since it is under compressive stresses which are orthogonal to the trench. The more complex pattern below the Cerro Galan ignimbrite complex and above the slab is interpreted to reflect delamination of continental lithosphere and upwelling of hot asthenosphere. The a-axes beneath the Cerro Galan, Cerro Blanco and Carachi Pampa volcanic centres at 100 km depth show some weak evidence for vertically orientated fast directions, which could be due to vertical asthenospheric flow around a delaminated block. Additionally, our splitting tomographic model shows that there is a significant amount of seismic anisotropy beneath the slab. The subslab mantle west of 68W shows roughly trench parallel horizontal a-axes that are probably driven by slab roll back and the relatively small coupling between the Nazca slab and the underlying mantle. In

[The Revista Médica del IMSS in the 2017 Healthcare Book Fair].

PubMed

Ramiro-H, Manuel; Acosta-Pérez, L; Cruz-Aranda, J E; García-Damián, J J; Miguel-Reyes, R; González-Martínez, R

2017-01-01

On August, the second edition of the Healthcare Book Fair took place, sponsored by the Facultad de Medicina of UNAM. Again, the Revista Médica del Instituto Mexicano del Seguro Social participated with a stand where we promoted it, talked about the different indexes where our journal is included, explained its objective and scope, and finally talked about its nature as an open access journal, which is aimed to the clinical staff of the different health institutions of our country.

Resultados del relevamiento de HI en el Cielo Austral: 3. Relevamiento de Nubes de Alta Velocidad

NASA Astrophysics Data System (ADS)

Morras, R.; Bajaja, E.; Arnal, E. M.; Pöppel, W. G. L.

Los resultados del relevamiento de HI del Hemisferio Austral fueron reprocesados con el fin de incrementar su sensibilidad. Así, se utilizó esta nueva base de datos con el fin de obtener un nuevo relevamiento de Nubes de Alta Velocidad en el cielo austral. El ruido r.m.s. alcanzado es de 0.015-0.020 K, con una resolución espectral de 8 km/seg. El cubrimiento espacial del relevamiento mejora en un factor 16 al realizado por Bajaja et al (1985).

[La Medicina del Lavoro: 100 volumes].

PubMed

Zocchetti, C

2009-01-01

With these pages La Medicina del Lavoro starts its 100th volume, so we have yet another historical occasion to celebrate the oldest occupational health journal in the world that is still publishing. Over the last few years we have had many occasions to celebrate, for example several anniversaries of the Journal (the 80th volume in 1989, 90 years in 1992, 100 years in 2001); the centenary of the foundation of the Clinica del Lavoro "Luigi Devoto" of Milan in 2001; the celebration of the 300 years' anniversary of the publication of De Morbis Artificum Diatriba by Bernardino Ramazzini, and we obviously hope to continue for many years to come in this positive outlook. One hundred volumes makes for a very large collection, with the highs and lows ofthe Journal's history (here we mean the variations in number of pages and physical size of the Journal). It is thanks to the Editors-in-chief(there have been very few so we can cite them all: Luigi Devoto, 1901-1936; Luigi Preti, 1936-1941; Enrico Vigliani, 1943-1992; e Vito Foà, 1992 to the present); the contributors who in various ways and with varying degrees of commitment but always with an exceptional personal participation, that it has been possible to reach 100 volumes, starting with C. Moreschi who, along with Luigi Devoto, was the first and sole editor at the Journal's foundation; up to the present extended and impressive editorial board; the printers (from the first. Tipografia Cooperativa, Via dei Molini in Pavia, to the latest: Casa Editrice Mattioli in Fidenza); the sponsors, including the most evident who, via advertising (rather limited as a matter offact), directly gave information about themselves, but also those who have often been or are behind the scenes, ensuring fundamental support which is not visible; content. articles, news, events, reports, ideas, opinions, photographs, tables, numbers... etc, which are really impossible to sum up. But the true collection which, for obvious reasons, cannot be

Relevamiento total del hemisferio sur celeste en la frecuencia de 1420 MHz

NASA Astrophysics Data System (ADS)

Bava, J. A.; Colomb, F. R.; Hurrel, E.; Larrarte, J. J.; Sanz, A. J.; Testori, J. C.; Reich, P.; Reich, W.; Wielebinski, R.

En el presente artículo se describe el relevamiento del cielo en el Hemisferio Sur Celeste en la frecuencia de 1420 MHz para declinaciones δ<= -19o realizado con la Antena II de 30 metros de diámetro del IAR. Este relevamiento posee igual sensibilidad (3xr.m.s=50 mK) que el realizado en el Hemisferio Norte con el radiotelescopio de 25 metros de Stockert de la Universidad de Bonn, operado por el Max-Planck Institute für Radioastronomie ( Reich W., 1982, A&ASS 48, 219; Reich P. and Reich W., 1986, A&ASS 63, 205). Con los datos obtenidos por ambos radiotelescopios se posee una base de datos de todo el cielo en esta frecuencia. En esta publicación presentamos los detalles del sistema receptor, técnicas de observación y reducción de datos, calibración y discusión de los errores en los resultados.

Adding up Stars in a Galaxy

NASA Image and Video Library

2009-08-19

NASA Galaxy Evolution Explorer spacecraft and Cerro Tololo Inter-American Observatory combined data making this diagram illustratrating the extent to which astronomers have been underestimating the proportion of small to big stars in certain galaxies.

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

PubMed Central

Stefano, Daniela De; Villella, Valeria R; Esposito, Speranza; Tosco, Antonella; Sepe, Angela; Gregorio, Fabiola De; Salvadori, Laura; Grassia, Rosa; Leone, Carlo A; Rosa, Giuseppe De; Maiuri, Maria C; Pettoello-Mantovani, Massimo; Guido, Stefano; Bossi, Anna; Zolin, Anna; Venerando, Andrea; Pinna, Lorenzo A; Mehta, Anil; Bona, Gianni; Kroemer, Guido; Maiuri, Luigi; Raia, Valeria

2014-01-01

Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine, have positive effects on mouse models of human cystic fibrosis (CF). These measures rescue the functional expression of the most frequent pathogenic CFTR mutant, F508del, at the respiratory epithelial surface and reduce lung inflammation in CftrF508del homozygous mice. Cysteamine, the reduced form of cystamine, is an FDA-approved drug. Here, we report that oral treatment with cysteamine greatly reduces the mortality rate and improves the phenotype of newborn mice bearing the F508del-CFTR mutation. Cysteamine was also able to increase the plasma membrane expression of the F508del-CFTR protein in nasal epithelial cells from F508del homozygous CF patients, and these effects persisted for 24 h after cysteamine withdrawal. Importantly, this cysteamine effect after washout was further sustained by the sequential administration of epigallocatechin gallate (EGCG), a green tea flavonoid, both in vivo, in mice, and in vitro, in primary epithelial cells from CF patients. In a pilot clinical trial involving 10 F508del-CFTR homozygous CF patients, the combination of cysteamine and EGCG restored BECN1, reduced SQSTM1 levels and improved CFTR function from nasal epithelial cells in vivo, correlating with a decrease of chloride concentrations in sweat, as well as with a reduction of the abundance of TNF/TNF-alpha (tumor necrosis factor) and CXCL8 (chemokine [C-X-C motif] ligand 8) transcripts in nasal brushing and TNF and CXCL8 protein levels in the sputum. Altogether, these results suggest that optimal schedules of cysteamine plus EGCG might be used for the treatment of CF caused by the F508del-CFTR mutation. PMID:25350163

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.

PubMed

De Stefano, Daniela; Villella, Valeria R; Esposito, Speranza; Tosco, Antonella; Sepe, Angela; De Gregorio, Fabiola; Salvadori, Laura; Grassia, Rosa; Leone, Carlo A; De Rosa, Giuseppe; Maiuri, Maria C; Pettoello-Mantovani, Massimo; Guido, Stefano; Bossi, Anna; Zolin, Anna; Venerando, Andrea; Pinna, Lorenzo A; Mehta, Anil; Bona, Gianni; Kroemer, Guido; Maiuri, Luigi; Raia, Valeria

2014-01-01

Restoration of BECN1/Beclin 1-dependent autophagy and depletion of SQSTM1/p62 by genetic manipulation or autophagy-stimulatory proteostasis regulators, such as cystamine, have positive effects on mouse models of human cystic fibrosis (CF). These measures rescue the functional expression of the most frequent pathogenic CFTR mutant, F508del, at the respiratory epithelial surface and reduce lung inflammation in Cftr(F508del) homozygous mice. Cysteamine, the reduced form of cystamine, is an FDA-approved drug. Here, we report that oral treatment with cysteamine greatly reduces the mortality rate and improves the phenotype of newborn mice bearing the F508del-CFTR mutation. Cysteamine was also able to increase the plasma membrane expression of the F508del-CFTR protein in nasal epithelial cells from F508del homozygous CF patients, and these effects persisted for 24 h after cysteamine withdrawal. Importantly, this cysteamine effect after washout was further sustained by the sequential administration of epigallocatechin gallate (EGCG), a green tea flavonoid, both in vivo, in mice, and in vitro, in primary epithelial cells from CF patients. In a pilot clinical trial involving 10 F508del-CFTR homozygous CF patients, the combination of cysteamine and EGCG restored BECN1, reduced SQSTM1 levels and improved CFTR function from nasal epithelial cells in vivo, correlating with a decrease of chloride concentrations in sweat, as well as with a reduction of the abundance of TNF/TNF-alpha (tumor necrosis factor) and CXCL8 (chemokine [C-X-C motif] ligand 8) transcripts in nasal brushing and TNF and CXCL8 protein levels in the sputum. Altogether, these results suggest that optimal schedules of cysteamine plus EGCG might be used for the treatment of CF caused by the F508del-CFTR mutation.

Screening for F508del as a first step in the molecular diagnosis of cystic fibrosis.

PubMed

Marson, Fernando Augusto de Lima; Bertuzzo, Carmen Silvia; Ribeiro, Maria Ângela Gonçalves de Oliveira; Ribeiro, Antônio Fernando; Ribeiro, José Dirceu

2013-01-01

To determine the relevance of screening for the F508del mutation of the cystic fibrosis transmembrane conductance regulator gene as a first step in the genetic diagnosis of cystic fibrosis (CF) by associating the genotype with various clinical variables. We evaluated 180 CF patients regarding the F508del mutation. The clinical data were obtained from the medical records of the patients and from interviews with their parents or legal guardians. Of the 180 patients studied, 65 (36.1%) did not carry the F508del mutation (group 0 [G0]), 67 (37.2%) were F508del heterozygous (G1), and 48 (26.7%) were F508del homozygous (G2). All three groups showed associations with the clinical variables. Homozygosis was associated with younger patients, younger age at CF diagnosis, and younger age at the first isolation of Pseudomonas aeruginosa (PA), as well as with higher prevalence of pancreatic insufficiency (PI) and non-mucoid PA (NMPA) colonization. In comparison with G1+G2 patients, G0 patients were older; first experienced clinical symptoms, digestive disease, and pulmonary disease at an older age; were older at CF diagnosis and at first PA isolation; and had a lower prevalence of PI and meconium ileus, as well as of colonization by NMPA, mucoid PA, and Burkholderia cepacia. In G1 patients, values were intermediate for age at CF diagnosis; age at first PA isolation, first pulmonary symptoms, and first clinical manifestations; MPA colonization; and OR for PI. The identification of F508del in 63.9% of the patients studied showed that this can be a useful tool as a first step in the genetic diagnosis of CF. The F508del genotype was associated with clinical severity of the disease, especially with the variables related to CF onset.

Identificación de los miembros del cúmulo NGC 2516

NASA Astrophysics Data System (ADS)

de Elía, G. C.; Orellana, R. B.

El cúmulo abierto NGC 2516 (α = 7h 58m y δ = -60o 45') tiene una edad de, aproximadamente, 150 Myr. El análisis de este sistema es particularmente importante en el Hemisferio Sur debido a su abundancia de estrellas peculiares y muy estudiado aplicando técnicas fotométricas, pero muy poco analizado desde el punto de vista astrométrico. A partir de una placa obtenida en el Observatorio Astronómico de La Plata y observaciones más actuales, nos hemos abocado al estudio de los movimientos propios de este cúmulo con el fin de determinar la pertenencia al mismo de las estrellas del campo de dicho cúmulo. Luego de llevar a cabo la determinación de los movimientos propios de todas las estrellas a partir de las posiciones obtenidas de la placa existente en el Observatorio de La Plata de 1914 y leídas con la MAMA en París, las observaciones realizadas con el círculo meridiano de San Fernando que se encuentra en el Observatorio Félix Aguilar de San Juan y las posiciones existentes en los catálogos AC 2000, Tycho, USNO y UCAC, programamos el método de Vasilevsky y Sanders para determinar la pertenencia de las estrellas de la región al cúmulo en cuestión. En un paso posterior, se realizó una modificación al método anterior para la determinación de los miembros. En esta modificación se consideró la densidad de las estrellas del cúmulo y la densidad de estrellas de campo. Esto permitió evaluar la pertenencia, no sólo a partir del movimiento propio de las estrellas, sino también a partir de la posición de las mismas con respecto al centro del cúmulo. También se consideró la dependencia de los parámetros con la magnitud. Los resultados así obtenidos fueron comparados con otras investigaciones de movimientos propios de la región del cúmulo. El movimiento propio absoluto del cúmulo fue comparado con el obtenido a partir de los catálogos estelares. Se encontró que los resultados coincidían para estrellas brillantes (magnitud más brillante que

Modeling visibility in the Paso del Norte (PDN) Region

NASA Astrophysics Data System (ADS)

Medina Calderon, Richard

Poor visibility is a subject of growing public concern throughout the U.S, and an active area of research. Its societal impacts on air quality, aviation transport and traffic are significant. Aerosols play a fundamental role in the attenuation of solar radiation, and also affect visibility. The scattering and extinction coefficients of aerosol particles in the Paso del Norte Region have been calculated using the T- matrix model in conjunction with a laser particle counter. Inter-comparison of the model's results of the scattering and absorption coefficients against the corresponding data from a Photoacustic extinctiometer instrument (which measures in-situ absorption and scattering coefficients of aerosol particles) shows excellent agreement. In addition, the volume-weighted method is used to determine the composite index of refraction which is representative of the aerosols for the Paso del Norte Region to obtain information of the type of aerosol particles present in the Region. The Single Scattering Albedo has also been retrieved using this methodology to obtain further insight into the type of aerosols present on a given day. Finally, the Koschmieder equation has been used to calculate the visual range or visibility, and was correlated with the PM2.5 and PM10 particle concentration present in the Region. Our methodology will allow a better understanding of the size and type of aerosol particles that are most detrimental to the visibility for the Paso Del Norte Region.

Oldest record of Mathildellidae (Crustacea: Decapoda: Goneplacoidea) associated with Retroplumidae from the Upper Cretaceous of NE Mexico

NASA Astrophysics Data System (ADS)

Vega, Francisco J.; Ahyong, Shane T.; Espinosa, Belinda; Flores-Ventura, José; Luna, Laura; González-González, Arturo H.

2018-03-01

A new genus and species of the Mathildellidae Prebranchioplax cretacica (Crustacea: Decapoda: Goneplacoidea) is reported from shallow marine sediments of the upper Campanian Parras Shale and Cerro del Pueblo Formation (Parras Basin), Coahuila, NE Mexico. Prebranchioplax cretacica was collected from siliceous concretions associated with more abundant specimens of the retroplumid Costacopluma mexicana Vega and Perrilliat, 1989. P. cretacica bears similarities to Eocene species of Branchioplax from Japan, USA (Alaska and Washington), England, Hungary and Tajikistan as well as with Eogeryonidae (Portunoidea) species from the Upper Cretaceous of Spain and Marocarcinidae (Styracocarcinus) from Morocco. However, clear differences in the carapace frontal shape places P. cretacica in the Mathildellidae. This record represents the oldest known Mathildellidae, and along with the Retroplumidae, appear to have originated during the Late Cretaceous in ancient seas of Mexico, with a wide distribution during Paleogene times becoming restricted today to deep waters of the Indo-Pacific region and Atlantic Ocean. Comments on preservation and morphology of Costacopluma mexicana are also included. Crab specimens preserved in siliceous concretions from one locality (Entronque) show peculiar desiccation marks, and a possible model of taphonomy.

Highly preferential association of NonF508del CF mutations with the M470 allele.

PubMed

Ciminelli, B M; Bonizzato, A; Bombieri, C; Pompei, F; Gabaldo, M; Ciccacci, C; Begnini, A; Holubova, A; Zorzi, P; Piskackova, T; Macek, M; Castellani, C; Modiano, G; Pignatti, P F

2007-01-01

On the basis of previous findings on random individuals, we hypothesized a preferential association of CF causing mutations with the M allele of the M470V polymorphic site of the CFTR gene. We have determined the M/V-CF mutation haplotype in a series of 201 North East Italian and 73 Czech CF patients who were not F508del homozygotes, as F508del was already known to be fully associated with the M allele. Out of 358 not F508del CF genes, 84 carried the V allele and 274 the less common M allele. In the N-E Italian population, MM subjects have a risk of carrying a CF causing mutation 6.9x greater than VV subjects when F508del is excluded and 15.4x when F508del is included. In the Czech population a similar, although less pronounced, association is observed. Besides the possible biological significance of this association, the possibility of exploiting it for a pilot screening program has been explored in a local North East Italian population for which CF patients were characterized for their CF mutation. General M470V genotyping followed by common CF mutation screening limited to couples in which each partner carries at least one M allele would need testing only 39% of the couples, which contribute 89% of the total risk, with a cost benefit.

Age- and Tumor Subtype–Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers

PubMed Central

Hogervorst, Frans; van Hien, Richard; Cornelissen, Sten; Broeks, Annegien; Adank, Muriel A.; Meijers, Hanne; Waisfisz, Quinten; Hollestelle, Antoinette; Schutte, Mieke; van den Ouweland, Ans; Hooning, Maartje; Andrulis, Irene L.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Antoniou, Antonis C.; Arndt, Volker; Bermisheva, Marina; Bogdanova, Natalia V.; Bolla, Manjeet K.; Brauch, Hiltrud; Brenner, Hermann; Brüning, Thomas; Burwinkel, Barbara; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Couch, Fergus J.; Cox, Angela; Cross, Simon S.; Czene, Kamila; Dunning, Alison M.; Fasching, Peter A.; Figueroa, Jonine; Fletcher, Olivia; Flyger, Henrik; Galle, Eva; García-Closas, Montserrat; Giles, Graham G.; Haeberle, Lothar; Hall, Per; Hillemanns, Peter; Hopper, John L.; Jakubowska, Anna; John, Esther M.; Jones, Michael; Khusnutdinova, Elza; Knight, Julia A.; Kosma, Veli-Matti; Kristensen, Vessela; Lee, Andrew; Lindblom, Annika; Lubinski, Jan; Mannermaa, Arto; Margolin, Sara; Meindl, Alfons; Milne, Roger L.; Muranen, Taru A.; Newcomb, Polly A.; Offit, Kenneth; Park-Simon, Tjoung-Won; Peto, Julian; Pharoah, Paul D.P.; Robson, Mark; Rudolph, Anja; Sawyer, Elinor J.; Schmutzler, Rita K.; Seynaeve, Caroline; Soens, Julie; Southey, Melissa C.; Spurdle, Amanda B.; Surowy, Harald; Swerdlow, Anthony; Tollenaar, Rob A.E.M.; Tomlinson, Ian; Trentham-Dietz, Amy; Vachon, Celine; Wang, Qin; Whittemore, Alice S.; Ziogas, Argyrios; van der Kolk, Lizet; Nevanlinna, Heli; Dörk, Thilo; Bojesen, Stig; Easton, Douglas F.

2016-01-01

Purpose CHEK2*1100delC is a well-established breast cancer risk variant that is most prevalent in European populations; however, there are limited data on risk of breast cancer by age and tumor subtype, which limits its usefulness in breast cancer risk prediction. We aimed to generate tumor subtype- and age-specific risk estimates by using data from the Breast Cancer Association Consortium, including 44,777 patients with breast cancer and 42,997 controls from 33 studies genotyped for CHEK2*1100delC. Patients and Methods CHEK2*1100delC genotyping was mostly done by a custom Taqman assay. Breast cancer odds ratios (ORs) for CHEK2*1100delC carriers versus noncarriers were estimated by using logistic regression and adjusted for study (categorical) and age. Main analyses included patients with invasive breast cancer from population- and hospital-based studies. Results Proportions of heterozygous CHEK2*1100delC carriers in controls, in patients with breast cancer from population- and hospital-based studies, and in patients with breast cancer from familial- and clinical genetics center–based studies were 0.5%, 1.3%, and 3.0%, respectively. The estimated OR for invasive breast cancer was 2.26 (95%CI, 1.90 to 2.69; P = 2.3 × 10−20). The OR was higher for estrogen receptor (ER)–positive disease (2.55 [95%CI, 2.10 to 3.10; P = 4.9 × 10−21]) than it was for ER-negative disease (1.32 [95%CI, 0.93 to 1.88; P = .12]; P interaction = 9.9 × 10−4). The OR significantly declined with attained age for breast cancer overall (P = .001) and for ER-positive tumors (P = .001). Estimated cumulative risks for development of ER-positive and ER-negative tumors by age 80 in CHEK2*1100delC carriers were 20% and 3%, respectively, compared with 9% and 2%, respectively, in the general population of the United Kingdom. Conclusion These CHEK2*1100delC breast cancer risk estimates provide a basis for incorporating CHEK2*1100delC into breast cancer risk prediction models and into

Estudio fenomenologico del conocimiento curricular y conocimiento de contenido en maestros de matematica a nivel secundario

NASA Astrophysics Data System (ADS)

Cardona Tomassini, Ivan Javier

En esta investigacion se estudio el fenomeno del conocimiento de contenido y el conocimiento curricular de maestros de matermaticas y como estos dos componentes se reflejan en su conocimiento pedagogico del contenido. El conocimiento de contenido es el conocimiento que tienen los maestros de los contenidos de una disciplina y sobre la estructura de su organizacion (Shulman, 1986). El conocimiento curricular es el conocimiento que los maestros poseen sobre los componentes de un curriculo disenado para ensenar un topico de una materia especifica a un nivel particular, la variedad de instrumentos instruccionales disponibles para implementar el mismo y como utilizar los instrumentos curriculares disponibles (Ball & Bass, 2003; Choppin, 2009; Hill, Rowan, & Ball, 2005). Este estudio se enmarca en el paradigma cualitativo, teniendo como diseno el estudio fenomenologico (Lucca y Berrios, 2009; McMillan, 2004). Los participantes fueron seis maestros de matermaticas del nivel superior (10mo a 12mo grado). Al momento de la investigacion los participantes ensenaban en escuelas publicas o privadas de Puerto Rico. Para recolectar la informacion se utilizo un grupo focal en donde los maestros resolvieron seis ejercicios matematicos y posteriormente reflexionaron en forma grupal sobre las soluciones. Tambien se realizo un analisis de documentos de planificacion y se llevaron a cabo entrevistas semiestructuradas. Se exploraron los contenidos relacionados a la ecuacion de una recta, rectas verticales y horizontales, suma y multiplicacion de polinomios, resolucion de ecuaciones cuadraticas y distancia entre dos puntos del plano cartesiano. Los resultados muestran que los participantes tienen dominio procesal de los contenidos correspondientes a las rectas verticales y horizontales, la suma y multiplicacion de polinomios, el calculo distancia entre dos puntos del plano cartesiano. Sin embargo, se noto cierta dificultad en la explicacion conceptual de los contenidos relacionados a la

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.

PubMed

Schmidt, Marjanka K; Hogervorst, Frans; van Hien, Richard; Cornelissen, Sten; Broeks, Annegien; Adank, Muriel A; Meijers, Hanne; Waisfisz, Quinten; Hollestelle, Antoinette; Schutte, Mieke; van den Ouweland, Ans; Hooning, Maartje; Andrulis, Irene L; Anton-Culver, Hoda; Antonenkova, Natalia N; Antoniou, Antonis C; Arndt, Volker; Bermisheva, Marina; Bogdanova, Natalia V; Bolla, Manjeet K; Brauch, Hiltrud; Brenner, Hermann; Brüning, Thomas; Burwinkel, Barbara; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Couch, Fergus J; Cox, Angela; Cross, Simon S; Czene, Kamila; Dunning, Alison M; Fasching, Peter A; Figueroa, Jonine; Fletcher, Olivia; Flyger, Henrik; Galle, Eva; García-Closas, Montserrat; Giles, Graham G; Haeberle, Lothar; Hall, Per; Hillemanns, Peter; Hopper, John L; Jakubowska, Anna; John, Esther M; Jones, Michael; Khusnutdinova, Elza; Knight, Julia A; Kosma, Veli-Matti; Kristensen, Vessela; Lee, Andrew; Lindblom, Annika; Lubinski, Jan; Mannermaa, Arto; Margolin, Sara; Meindl, Alfons; Milne, Roger L; Muranen, Taru A; Newcomb, Polly A; Offit, Kenneth; Park-Simon, Tjoung-Won; Peto, Julian; Pharoah, Paul D P; Robson, Mark; Rudolph, Anja; Sawyer, Elinor J; Schmutzler, Rita K; Seynaeve, Caroline; Soens, Julie; Southey, Melissa C; Spurdle, Amanda B; Surowy, Harald; Swerdlow, Anthony; Tollenaar, Rob A E M; Tomlinson, Ian; Trentham-Dietz, Amy; Vachon, Celine; Wang, Qin; Whittemore, Alice S; Ziogas, Argyrios; van der Kolk, Lizet; Nevanlinna, Heli; Dörk, Thilo; Bojesen, Stig; Easton, Douglas F

2016-08-10

CHEK2*1100delC is a well-established breast cancer risk variant that is most prevalent in European populations; however, there are limited data on risk of breast cancer by age and tumor subtype, which limits its usefulness in breast cancer risk prediction. We aimed to generate tumor subtype- and age-specific risk estimates by using data from the Breast Cancer Association Consortium, including 44,777 patients with breast cancer and 42,997 controls from 33 studies genotyped for CHEK2*1100delC. CHEK2*1100delC genotyping was mostly done by a custom Taqman assay. Breast cancer odds ratios (ORs) for CHEK2*1100delC carriers versus noncarriers were estimated by using logistic regression and adjusted for study (categorical) and age. Main analyses included patients with invasive breast cancer from population- and hospital-based studies. Proportions of heterozygous CHEK2*1100delC carriers in controls, in patients with breast cancer from population- and hospital-based studies, and in patients with breast cancer from familial- and clinical genetics center-based studies were 0.5%, 1.3%, and 3.0%, respectively. The estimated OR for invasive breast cancer was 2.26 (95%CI, 1.90 to 2.69; P = 2.3 × 10(-20)). The OR was higher for estrogen receptor (ER)-positive disease (2.55 [95%CI, 2.10 to 3.10; P = 4.9 × 10(-21)]) than it was for ER-negative disease (1.32 [95%CI, 0.93 to 1.88; P = .12]; P interaction = 9.9 × 10(-4)). The OR significantly declined with attained age for breast cancer overall (P = .001) and for ER-positive tumors (P = .001). Estimated cumulative risks for development of ER-positive and ER-negative tumors by age 80 in CHEK2*1100delC carriers were 20% and 3%, respectively, compared with 9% and 2%, respectively, in the general population of the United Kingdom. These CHEK2*1100delC breast cancer risk estimates provide a basis for incorporating CHEK2*1100delC into breast cancer risk prediction models and into guidelines for intensified screening and follow-up. © 2016

Effect of the F508del genotype on outcomes of endoscopic sinus surgery in children with cystic fibrosis.

PubMed

Do, Bao Anh Julie; Lands, Larry C; Saint-Martin, Christine; Mascarella, Marco A; Manoukian, John J; Daniel, Sam J; Nguyen, Lily H P

2014-07-01

Numerous authors have sought to describe genotype-phenotype correlations in cystic fibrosis (CF), notably to pancreatic insufficiency and lung disease. However, few studies have focused on the association between the F508del genotype and response to sinus surgery. The objective of this study is to assess the effect of the F508del genotype on sinonasal disease severity and outcomes following functional endoscopic sinus surgery (FESS) in a pediatric population. A retrospective chart review of 153 children with CF seen at a tertiary care pediatric hospital from 1995 to 2008 was performed. Patients were classified into one of three groups according to F508del genotype, either as homozygous, heterozygous or not carrying a F508del mutation. The sinonasal disease phenotype of the three groups was compared based on clinical and radiological findings, extent of endoscopic sinus surgery and rate of revision surgery. The relationship between the F508del genotype and pancreatic insufficiency was confirmed (p<0.05). There was no association between the F508del genotype and increased need for FESS (p=0.75). Moreover, no association was established between F508del homozygosity and presence of nasal polyps, Lund-Mackay score, extent of surgery or length of postoperative hospitalization. The rates of revision surgery did not differ significantly among the three genotypes analyzed (p=0.59). There is no clear association between the F508del genotype and an increased need for FESS, extent of surgery, or revision surgery. Given the phenotypic variability of sinonasal disease in patients with CF, a prospective study is needed to better understand outcomes following FESS and the contribution of gene modifiers to this effect. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

[Seventy years of medicine in the Instituto Mexicano del Seguro Social].

PubMed

Fajardo-Ortiz, Guillermo

2014-01-01

The purpose of these lines is to remember and refer some of the historical landmarks in the evolution of the medical services of the Instituto Mexicano del Seguro Social (IMSS, according to its initials in Spanish) since it was founded, in 1943. We also want to bring to the reader's attention that the dimensions and impacts on health that IMSS has achieved, throughout its history, have strengthened the citizenship, as well as social sustainability. Also, those impacts have determined the creation and the reinforcement of human capital in México. Throughout this concise balance, all the controversy surrounding the foundation of the Institute is being recalled (the protest in the Mexico City Zócalo, or the attack to an hospital in San Ángel -a neighborhood located in the Southwest of Mexico City-), as well as the way the IMSS incorporated several words into the vocabulary of Mexicans. We also remember the previous antecedent of the Revista Médica del Instituto Mexicano del Seguro Social, as well as the Revista de Enfermería, and the emblematic Archives of Medical Research. The IMSS has 70 years of achievements, seven decades covered.

Medición de densidades medias de meteoritos: test del método de inmersión

NASA Astrophysics Data System (ADS)

Steren, G.

Se evaluó una técnica simple para medir las densidades medias de meteoritos, basada en el Método de Arquímedes y que utiliza cuentas de vidrio de 40μ en lugar de un fluído esto presenta la ventaja de no ser intrusivo ni químicamente reactivo (D.Britt and G.Consolmagno, 1996, B.A.A.S.28,1106). El estudio, realizado en junio de este año por participantes de la VI Escuela de Verano del Observatorio del Vaticano, empleó 37 muestras de la colección del Observatorio del Vaticano, de las cuales 26 eran Condritas, 1 Pallasita y 1 Howardita; algunas de ellas ya habian sido estudiadas por otras técnicas aunque también se incluyeron muestras no estudiadas anteriormente.

VizieR Online Data Catalog: Near-infrared variability in RCW 38 (Doerr+, 2013)

NASA Astrophysics Data System (ADS)

Doerr, M.; Chini, R.; Haas, M.; Lemke, R.; Nuernberger, D.

2013-03-01

Observations were carried out using the 80cm IRIS telescope of the Universitaetssternwarte Bochum near Cerro Armazones, Chile at an altitude of 2817m. The monitoring campaign was scheduled from January to March 2011. (2 data files).

A chemical corrector modifies the channel function of F508del-CFTR.

PubMed

Kim Chiaw, Patrick; Wellhauser, Leigh; Huan, Ling Jun; Ramjeesingh, Mohabir; Bear, Christine E

2010-09-01

The deletion of Phe-508 (F508del) constitutes the most prevalent cystic fibrosis-causing mutation. This mutation leads to cystic fibrosis transmembrane conductance regulator (CFTR) misfolding and retention in the endoplasmic reticulum and altered channel activity in mammalian cells. This folding defect can however be partially overcome by growing cells expressing this mutant protein at low (27 degrees C) temperature. Chemical "correctors" have been identified that are also effective in rescuing the biosynthetic defect in F508del-CFTR, thereby permitting its functional expression at the cell surface. The mechanism of action of chemical correctors remains unclear, but it has been suggested that certain correctors [including 4-cyclohexyloxy-2-(1-[4-(4-methoxy-benzenesulfonyl)-piperazin-1-yl]-ethyl)-quinazoline (VRT-325)] may act to promote trafficking by interacting directly with the mutant protein. To test this hypothesis, we assessed the effect of VRT-325 addition on the channel activity of F508del-CFTR after its surface expression had been "rescued" by low temperature. It is noteworthy that short-term pretreatment with VRT-325 [but not with an inactive analog, 4-hydroxy-2-(1-[4-(4-methoxy-benzenesulfonyl)-piperazin-1-yl]-ethyl)-quinazoline (VRT-186)], caused a modest but significant inhibition of cAMP-mediated halide flux. Furthermore, VRT-325 decreased the apparent ATP affinity of purified and reconstituted F508del-CFTR in our ATPase activity assay, an effect that may account for the decrease in channel activity by temperature-rescued F508del-CFTR. These findings suggest that biosynthetic rescue mediated by VRT-325 may be conferred (at least in part) by direct modification of the structure of the mutant protein, leading to a decrease in its ATP-dependent conformational dynamics. Therefore, the challenge for therapy discovery will be the design of small molecules that bind to promote biosynthetic maturation of the major mutant without compromising its activity in

DK phocomelia phenotype (von Voss-Cherstvoy syndrome) caused by somatic mosaicism for del(13q).

PubMed

Bamforth, J S; Lin, C C

1997-12-31

DK phocomelia (von Voss-Cherstvoy syndrome) is a rare condition characterized by radial ray defects, occipital encephalocoele, and urogenital abnormalities. Lubinsky et al. [1994: Am J Med Genet 52:272-278] pointed out similarities between this and the del(13q) syndrome. To date, all reported cases of DK phocomelia have been apparently normal chromosomally. We report on a case of DK phocomelia in which the proposita had normal lymphocyte chromosomes, but was mosaic in fibroblasts for del(13)(q12). Fibroblast chromosomes studies on other cases of DK phocomelia have not been reported: this raises the possibility that some cases of DK phocomelia may be somatic mosaics for del(13)(q12).

Cirugía de los trastornos del comportamiento: el estado del arte

PubMed Central

Yampolsky, Claudio; Bendersky, Damián

2014-01-01

Introducción: La cirugía de los trastornos del comportamiento (CTC) se está convirtiendo en un tratamiento más común desde el desarrollo de la neuromodulación. Métodos: Este artículo es una revisión no sistemática de la historia, indicaciones actuales, técnicas y blancos quirúrgicos de la CTC. Dividimos su historia en 3 eras: la primera comienza en los inicios de la psicocirugía y termina con el desarrollo de las tícnicas estereotácticas, cuando comienza la segunda era. Ésta se caracteriza por la realización de lesiones estereotácticas. Nos encontramos transitando la tercera era, que comienza cuando la estimulación cerebral profunda (ECP) comienza a ser usada en CTC. Resultados: A pesar de los errores graves cometidos en el pasado, hoy en día, la CTC está renaciendo. Los trastornos psiquiátricos que se más frecuentemente se tratan con cirugía son: depresión refractaria, trastorno obsesivo-compulsivo y síndrome de Tourette. Además, algunos pacientes con agresividad fueron tratados quirúrgicamente. Hay varios blancos estereotácticos descriptos para estos trastornos. La estimulación vagal puede ser usada también para depresión. Conclusión: Los resultados de la ECP en estos trastornos parecen alentadores. Sin embargo, se necesitan más estudios randomizados para establecer la efectividad de la CTC. Debe tenerse en cuenta que una apropiada selección de pacientes nos ayudará a realizar un procedimiento más seguro así como también a lograr mejores resultados quirúrgicos, conduciendo a la CTC a ser más aceptada por psiquiatras, pacientes y sus familias. Se necesita mayor investigación en varios temas como: fisiopatología de los trastornos del comportamiento, indicaciones de CTC y nuevos blancos quirúrgicos. PMID:25165612

Excess breast cancer risk in first degree relatives of CHEK2∗1100delC positive familial breast cancer cases.

PubMed

Adank, Muriel A; Verhoef, Senno; Oldenburg, Rogier A; Schmidt, Marjanka K; Hooning, Maartje J; Martens, John W M; Broeks, Annegien; Rookus, Matti; Waisfisz, Quinten; Witte, Birgit I; Jonker, Marianne A; Meijers-Heijboer, Hanne

2013-05-01

The CHEK2∗1100delC mutation confers a relative risk of two for breast cancer (BC) in the general population. This study aims to explore the excess cancer risk due to the CHEK2∗1100delC mutation within a familial non-BRCA1/2 breast cancer setting. Cancer incidences were compared between first degree relatives of 107 familial breast cancer patients positive for the CHEK2∗1100delC mutation (CHEK2 positive families) and first degree relatives of 314 familial breast cancer patients without the CHEK2∗1100delC mutation (CHEK2 negative families). All families were derived from the same pool of familial non-BRCA1/2 breast cancer families (n=2554). Medical information of 2188 first degree relatives of these families was analysed for cancer risk. CHEK2∗1100delC status of relatives was unknown. Increased breast cancer risk (hazard ratio (HR) 2.0 (95% confidence interval (CI): 1.4-2.7), p<0.001) was observed in sisters of CHEK2∗1100delC positive index cases compared to sisters of CHEK2∗1100delC negative index cases. HR was 1.6 (95% CI: 1.0-2.4) for mothers of CHEK2 positive versus negative index cases (p=0.041). For second primary breast cancers HR was increased in CHEK2∗1100delC positive index cases (HR 2.1, 95% CI: 1.3-3.3, p=0.003) and their sisters (HR 2.6, 95% CI: 1.1-6.1, p=0.025). There is an excess breast cancer risk in first degree relatives of CHEK2∗1100delC positive non-BRCA1/2 familial breast cancer patients compared to non-CHEK2∗1100delC familial breast cancer relatives. Genotyping for the CHEK2∗1100delC mutation in a familial breast cancer setting contributes to optimal clinical surveillance in countries in which this mutation is prevalent. Carriers and female relatives are eligible for stringent breast surveillance programs. Copyright © 2013 Elsevier Ltd. All rights reserved.

A Lesson in Counting Stars

NASA Image and Video Library

2009-08-19

These two photographs were made by combining data from NASA Galaxy Evolution Explorer spacecraft and the Cerro Tololo Inter-American Observatory in Chile to learn that not all galaxies make stars of different sizes in the same quantities.

Species identification in forensic samples using the SPInDel approach: A GHEP-ISFG inter-laboratory collaborative exercise.

PubMed

Alves, Cíntia; Pereira, Rui; Prieto, Lourdes; Aler, Mercedes; Amaral, Cesar R L; Arévalo, Cristina; Berardi, Gabriela; Di Rocco, Florencia; Caputo, Mariela; Carmona, Cristian Hernandez; Catelli, Laura; Costa, Heloísa Afonso; Coufalova, Pavla; Furfuro, Sandra; García, Óscar; Gaviria, Anibal; Goios, Ana; Gómez, Juan José Builes; Hernández, Alexis; Hernández, Eva Del Carmen Betancor; Miranda, Luís; Parra, David; Pedrosa, Susana; Porto, Maria João Anjos; Rebelo, Maria de Lurdes; Spirito, Matteo; Torres, María Del Carmen Villalobos; Amorim, António; Pereira, Filipe

2017-05-01

DNA is a powerful tool available for forensic investigations requiring identification of species. However, it is necessary to develop and validate methods able to produce results in degraded and or low quality DNA samples with the high standards obligatory in forensic research. Here, we describe a voluntary collaborative exercise to test the recently developed Species Identification by Insertions/Deletions (SPInDel) method. The SPInDel kit allows the identification of species by the generation of numeric profiles combining the lengths of six mitochondrial ribosomal RNA (rRNA) gene regions amplified in a single reaction followed by capillary electrophoresis. The exercise was organized during 2014 by a Working Commission of the Spanish and Portuguese-Speaking Working Group of the International Society for Forensic Genetics (GHEP-ISFG), created in 2013. The 24 participating laboratories from 10 countries were asked to identify the species in 11 DNA samples from previous GHEP-ISFG proficiency tests using a SPInDel primer mix and control samples of the 10 target species. A computer software was also provided to the participants to assist the analyses of the results. All samples were correctly identified by 22 of the 24 laboratories, including samples with low amounts of DNA (hair shafts) and mixtures of saliva and blood. Correct species identifications were obtained in 238 of the 241 (98.8%) reported SPInDel profiles. Two laboratories were responsible for the three cases of misclassifications. The SPInDel was efficient in the identification of species in mixtures considering that only a single laboratory failed to detect a mixture in one sample. This result suggests that SPInDel is a valid method for mixture analyses without the need for DNA sequencing, with the advantage of identifying more than one species in a single reaction. The low frequency of wrong (5.0%) and missing (2.1%) alleles did not interfere with the correct species identification, which demonstrated the

Rescue of murine F508del CFTR activity in native intestine by low temperature and proteasome inhibitors.

PubMed

Wilke, Martina; Bot, Alice; Jorna, Huub; Scholte, Bob J; de Jonge, Hugo R

2012-01-01

Most patients with Cystic Fibrosis (CF) carry at least one allele with the F508del mutation, resulting in a CFTR chloride channel protein with a processing, gating and stability defect, but with substantial residual activity when correctly sorted to the apical membranes of epithelial cells. New therapies are therefore aimed at improving the folding and trafficking of F508del CFTR, (CFTR correctors) or at enhancing the open probability of the CFTR chloride channel (CFTR potentiators). Preventing premature breakdown of F508del CFTR is an alternative or additional strategy, which is investigated in this study. We established an ex vivo assay for murine F508del CFTR rescue in native intestinal epithelium that can be used as a pre-clinical test for candidate therapeutics. Overnight incubation of muscle stripped ileum in modified William's E medium at low temperature (26°C), and 4 h or 6 h incubation at 37°C with different proteasome inhibitors (PI: ALLN, MG-132, epoxomicin, PS341/bortezomib) resulted in fifty to hundred percent respectively of the wild type CFTR mediated chloride secretion (forskolin induced short-circuit current). The functional rescue was accompanied by enhanced expression of the murine F508del CFTR protein at the apical surface of intestinal crypts and a gain in the amount of complex-glycosylated CFTR (band C) up to 20% of WT levels. Sustained rescue in the presence of brefeldin A shows the involvement of a post-Golgi compartment in murine F508del CFTR degradation, as was shown earlier for its human counterpart. Our data show that proteasome inhibitors are promising candidate compounds for improving rescue of human F508del CFTR function, in combination with available correctors and potentiators.

CHEK2*1100delC and risk of malignant melanoma: Danish and German studies and meta-analysis.

PubMed

Weischer, Maren; Heerfordt, Ida M; Bojesen, Stig E; Eigentler, Thomas; Garbe, Claus; Röcken, Martin; Hölmich, Lisbet Rosenkrantz; Schmidt, Henrik; Klyver, Helle; Bastholt, Lars; Nordestgaard, Børge G

2012-02-01

It is possible that reduced function of DNA repair and cell-cycle control genes increases the individual susceptibility to malignant melanoma. As CHEK2 is a cell-cycle master controller, we tested the hypothesis that heterozygosity for the frameshift alteration CHEK2*1100delC is associated with increased risk of malignant melanoma. First, we performed case-control studies of 1,152 Danish and 752 German individuals with malignant melanoma compared with 9,142 Danish and 3,718 German controls. Second, we performed a meta-analysis of CHEK2*1100delC and malignant melanoma, involving 2,619 cases and 17,481 controls. Third, we examined the risk of malignant melanoma associated with CHEK2*1100delC heterozygosity in an analysis stratified for sun exposure, as well as for subtype and location on the body. The odds ratios for malignant melanoma for CHEK2(*)1100del heterozygotes compared with those for noncarriers were 2.01 (95% confidence interval (CI), 1.03-3.91) in Danes, 1.42 (95% CI, 0.46-4.31) in Germans, and 1.79 (95% CI, 1.02-3.17) in Danes and Germans combined. In a meta-analysis, the odds ratio of malignant melanoma for CHEK2*1100delC heterozygotes compared with that for noncarriers was 1.81 (95% CI, 1.07-3.05). Stratifications did not alter these results. CHEK2*1100delC heterozygotes have a twofold risk of malignant melanoma compared with noncarriers.

Absence of CHEK2*1100delC mutation in families with hereditary breast cancer in North America.

PubMed

Iniesta, Maria D; Gorin, Michael A; Chien, Ling-Chen; Thomas, Samantha M; Milliron, Kara J; Douglas, Julie A; Merajver, Sofia D

2010-10-15

The CHEK2*1100delC mutation has been reported to confer a twofold increased risk of breast cancer among carriers. The frequency of the mutation varies among populations. The highest frequency has been described in Northern and Eastern European countries; the frequency may be much lower in North America. In this study, our aim was to determine the frequency of CHEK2*1100delC in members of breast cancer families who tested negative for a deleterious mutation in BRCA1/2 at the University of Michigan Comprehensive Cancer Center. We genotyped 102 members from 90 families for CHEK2*1100delC. Most of these families had several cases of breast cancer or ovarian cancer (or both), as well as multiple members with other cancer types in a single lineage. No CHEK2*1100delC mutations were detected in any of the 102 individuals, including 51 women diagnosed with breast cancer at an early age (<45 years), 8 women with bilateral breast cancer, 3 men with breast cancer, and 8 women with ovarian cancer. Our data are consistent with the reported very low frequency of CHEK2*1100delC mutations in North American populations (compared with Northern Europe), rendering CHEK2*1100delC such an unlikely culprit in BRCA1/2 negative families that routine testing of these families appears unwarranted. Copyright © 2010 Elsevier Inc. All rights reserved.

Gazetteer of El Salvador,

DTIC Science & Technology

1982-06-01

Cerro HLL 13 22’N 88 02’W ES07 CK87 ND16-10 H r ’t Cerru Mee El Garrobal. Loma MT 1338’N 88󈧗’W ES09 CL50 ND16-10(;,rzas., A’i- see Taisihuat, Rio STM...t’fias. RHi see Las Pifias, Rio STM 13 38’N 87 52"W ES07 DLOO ND16 IC I’iia.. Riode: see Las Pifias, Rio STM 13 38’N 87 52W ES07 DLOC ND6-1 Pineda PPL...ND16-10 San JoaqUljn, Cerro MT 13 50’N 88 39’W ES02 CL22 ND16-09 ’ n11m l𔃺 .IL-hotes. ,uebrada.- Mee La l)escabezada. Quebrada STMI 13 45’N 89 40W

Mini-mastoidectomía para anastomosis hipogloso-facial con sección parcial del nervio hipogloso

PubMed Central

Campero, Álvaro; Ajler, Pablo; Socolovsky, Mariano; Martins, Carolina; Rhoton, Albert

2012-01-01

Introducción: La anastomosis hipogloso-facial es la técnica de elección para la reparación de la parálisis facial cuando no se dispone de un cabo proximal sano del nervio facial. La técnica de anastomosis mediante fresado mastoideo y sección parcial del hipogloso minimiza la atrofia lingual sin sacrificar resultados a nivel facial. Método: La porción mastoidea del nervio facial transcurre por la pared anterior de la AM, a un promedio de 18+/-3 mm de profundidad respecto de la pared lateral. Se debe reconocer la cresta supramastoidea, desde la cual se marca una línea vertical paralela al eje mayor de la AM, 1 cm por detrás de la pared posterior del CAE El fresado se comienza desde la línea medio mastoidea hasta la pared posterior del CAE. Una vez encontrado el nervio facial en el tercio medio del canal mastoideo, el mismo es seguido hacia proximal y distal. Resultados: El abordaje descripto permite acceder al nervio facial intratemporal en su porción mastoidea, y efectuar un fresado óseo sin poner en riesgo al nervio o a estructuras vasculares cercanas. Se trata de un procedimiento técnicamente más sencillo que los abordajes amplios habitualmente utilizados al hueso temporal; no obstante su uso debe ser restringido mayormente a la anastomosis hipogloso-facial. Conclusión: Esta es una técnica relativamente sencilla, que puede ser reproducida por cirujanos sin mayor experiencia en el tema, luego de su paso por el laboratorio de anatomía. PMID:23596555

44 CFR 295.3 - Information and assistance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Mexico, 87544-1480, or telephone 1-888-748-1853 (toll free). The Cerro Grande Fire Assistance site on the World Wide Web can be accessed at http://www.fema.gov/cerrogrande. In the interest of brevity, we do not...

Reproductive biology of the Del Norte salamander (Plethodon elongatus).

Treesearch

Clara A. Wheeler; Hartwell H. Welsh Jr.; Lisa M. Ollivier

2013-01-01

We examined seasonal reproductive patterns of the Del Norte Salamander, Plethodon elongatus, in mixed conifer and hardwood forests of northwestern California and southwestern Oregon. Seasonal size differences in reproductive structures suggested that maximum spermatogenic activity occurred during the late summer, with spermatozoa transfer to the...

New records of fishes at Isla del Coco, Costa Rica

USGS Publications Warehouse

Garrison, V.H.

1996-01-01

Isla del Coco lies at 5 degrees 32'N latitude, 87 degrees 04'W longitude and is the sole peak of the Cocos Ridge exposed above sea level. This isolated island formed approximately 2 million years ago. It rises 575 m above the surface of the sea and covers 46 km2 (Castillo et aI., 1988). Five hundred km to the NNE is Costa Rica; 630 km SSW are the Galapagos Islands; 650 km to the E is Isla Malpelo, Colombia; and approximately 8,000 km W lie the Line Islands. Costa Rica claimed Isla del Coco in 1832 and declared it a National Park in 1978. The area of the park was increased to include the adjacent waters 5 km offshore in 1984 and 25 km offshore in 1991.

The CHEK2 del5395 is a founder mutation without direct effects for cancer risk in the latvian population.

PubMed

Plonis, J; Kalniete, D; Nakazawa-Miklasevica, M; Irmejs, A; Vjaters, E; Gardovskis, J; Miklasevics, E

2015-12-01

Our objective was to determine: 1) whether the checkpoint kinase 2 ( CHEK2 ) del5395 (g.27417113-27422508 del, NC_000022.11) is a founder mutation in the Latvian population, 2) if there is an association between CHEK2 del5395 mutation and cancer risk, and 3) and whether the CHEK2 del5395 mutation impacts cancer predisposition in Chernobyl disaster liquidators (the civil and military personnel who were called upon to deal with consequences of the 1986 nuclear disaster) as well as geriatric populations. We recruited 438 breast cancer patients, 568 colorectal cancer patients, 399 ovarian cancer patients, 419 prostate cancer patients, 526 healthy blood donors, 480 Chernobyl disaster liquidators and 444 geriatric cancer-free participants. DNA samples were isolated from blood samples and subjected to multiplex polymerase chain reaction (PCR). The truncation of del5395 was estimated by fragment size of the multiplex PCR.All groups were compared to the healthy blood donors using Fisher's exact test. All p values were two-sided and the odds ratios (OR) calculated by two-by-two table. In cancer groups, the del5395 mutation was most frequently observed in the ovarian cancer group (1.00%, OR = 1.32). In control groups, the del5395 mutation was most frequent (0.76%) in the healthy donors, which exceeded its frequency in the Chernobyl liquidators group and the geriatric group by 0.01 and 0.08%, respectively. For all groups, the OR appeared to be >1 only in ovarian cancer patients. However, OR rates showed no statistical significance in either cancer or control groups, with the p value fluctuating within the range of 0.39-1.00. The CHEK2 gene del5395 is a founder mutation in the Latvian population, which, however, does not have a direct impact on genetic predisposition toward colorectal, breast, ovarian and prostate cancer.

Seguridad del paciente en Radioterapia Intraoperatoria: Impacto de los elementos controlados por el Radiofisico

NASA Astrophysics Data System (ADS)

Tarjuelo, Juan Lopez

Introduccion: En la administracion de la radioterapia intervienen profesionales y equipos de tratamiento, por lo que existe el riesgo de error y se precisa que dicho equipamiento funcione conforme a lo esperado. A los radiofisicos les corresponde participar en las actividades de garantia o aseguramiento de la calidad, incluyendo el control de calidad de los equipos, y en la evaluacion de los riesgos asociados. La radioterapia intraoperatoria (RIO) es una tecnica radioterapica de intensificacion de dosis, altamente selectiva, dirigida a volumenes anatomicos restringidos durante el tratamiento quirurgico oncologico, basada en la administracion de una dosis absorbida alta por medio de un haz de electrones tras el examen visual directo del lecho tumoral. Como incorporar los ultimos avances en el refuerzo de la seguridad en radioterapia es una tarea ambiciosa y compleja, resulta mas concreta y de inmediata aplicacion su introduccion en la RIO. El objetivo es analizar los elementos que reducen los riesgos y aumentan la seguridad en la RIO y su dosimetria, y valorar la funcion del radiofisico en esta labor. Material y metodos: Se emplearon el planificador Radiance de GMV y el acelerador lineal de los tratamientos de RIO Elekta Precise, controlado con el verificador diario de haces Daily QA Check 1090 y medido con las camaras de ionizacion PPC 40, FC65-G y FC65-P de PTW-Freiburg, a su vez verificadas con fuentes radiactivas adecuadas de estroncio-90 modelos CDP y CDC de IBA Dosimetry. Se realizo un analisis de modos de fallo y efectos (failure mode and effect analysis, FMEA) con el fin de identificar los elementos que forman la RIO y aplicar las herramientas necesarias para la minimizacion de los riesgos y la mejora de la seguridad en la tecnica. Se estudiaron las verificaciones diarias de dicho acelerador Precise con el control estadistico de procesos (statistical process control, SPC) y se simularon intervenciones para devolverlo al estado llamado en control. El SPC

Association Between CHEK2*1100delC and Breast Cancer: A Systematic Review and Meta-Analysis.

PubMed

Liang, Mingming; Zhang, Yun; Sun, Chenyu; Rizeq, Feras Kamel; Min, Min; Shi, Tingting; Sun, Yehuan

2018-06-16

The association between the checkpoint kinase 2*1100delC (CHEK2*1100delC) and breast cancer has been extensively explored. In light of the recent publication of studies on these specific findings, particularly regarding male patients with breast cancer, we performed an updated meta-analysis to investigate a more reliable estimate. This meta-analysis included 26 published studies selected in a search of electronic databases up to January 2018, including 118,735 breast cancer cases and 195,807 controls. Odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the association between 1100delC and breast cancer. Meta-analysis results suggested that 1100delC contributed to an increased breast cancer risk in overall populations (OR 2.89; 95% CI 2.63-3.16). Subgroup analysis found ORs of 3.13 (95% CI 1.94-5.07) for male breast cancer, 2.88 (95% CI 2.63-3.16) for female breast cancer, 2.87 (95% CI 1.85-4.47) for early-onset breast cancer, 2.92 (95% CI 2.65-3.22) for invasive breast cancer, and 3.21 (95% CI 2.41-4.29) for familial breast cancer. The sensitivity analysis suggested that results of this meta-analysis were generally robust. CHEK2*1100delC is associated with an increased risk of both female and male breast cancer.

ASASSN1: Bright Comet Discovered by the All Sky Automated Survey for SuperNovae

NASA Astrophysics Data System (ADS)

Prieto, JJ. L.; Shappee, B. J.; Brimacombe, J.; Stanek, K. Z.; Chen, Ping; Dong, Subo; Holoien, T. W.-S.; Kochanek, C. S.; Brown, J. S.; Shields, J. V.; Thompson, T. A.

2017-07-01

During the ongoing All Sky Automated Survey for SuperNovae (ASAS-SN, Shappee et al. 2014), using data from the quadruple 14-cm "Cassius" telescope on Cerro Tololo, Chile, we discovered a new moving transient source, now confirmed as a comet.

[Genetic polymorphism and forensic application of 30 InDel loci of Han population in Beijing].

PubMed

Bai, Ru-Feng; Jiang, Li-Zhe; Zhang, Zhong; Shi, Mei-Sen

2013-12-01

To study the genetic diversities of 30 insertion-deletion (InDel) polymorphisms loci of Han population in Beijing, and to evaluate their forensic application, 210 unrelated healthy individuals of Han population in Beijing were investigated to determine the distributions of allele frequencies by using Investigator DIP system. The PCR products were detected with ABI 3130 XL Genetic Analyzer. Forensic parameters were calculated with relevant statistical analysis software. As a result, after the Bonferroni correction at a 95% significance level, there were no significant departures from Hardy-Weinberg equilibrium or significant linkage disequilibrium between the loci. The power of discrimination (DP) varies between 0.2690 (HLD118) and 0.6330 (HLD45), and the combined discrimination power (TDP) for the 30 InDel loci is 0.999999999985. The combined power of exclusion was 0.98771049 in trio cases (CPE(trio)) and 0.94579456 in duo cases (CPE(duo)). The parentage testing of 32 cases revealed no mutations happened to 30 InDel loci. Multiplex detection of the 30 InDel loci revealed a highly polymorphic genetic distribution in Beijing Han population, which represents a complementary tool in human identification studies, especially in challenging DNA cases.

Spatiotemporal evolution of dehydration reactions in subduction zones (Invited)

NASA Astrophysics Data System (ADS)

Padron-Navarta, J.

2013-12-01

Large-scale deep water cycling takes place through subduction zones in the Earth, making our planet unique in the solar system. This idiosyncrasy is the result of a precise but unknown balance between in-gassing and out-gassing fluxes of volatiles. Water is incorporated into hydrous minerals during seafloor alteration of the oceanic lithosphere. The cycling of volatiles is triggered by dehydration of these minerals that release fluids from the subducting slab to the mantle wedge and eventually to the crust or to the deep mantle. Whereas the loci of such reactions are reasonably well established, the mechanisms of fluid migration during dehydration reactions are still barely known. One of the challenges is that dehydration reactions are dynamic features evolving in time and space. Experimental data on low-temperature dehydration reactions (i.e. gypsum) and numerical models applied to middle-crust conditions point to a complex spatiotemporal evolution of the dehydration process. The extrapolation of these inferences to subduction settings has not yet been explored but it is essential to understand the dynamism of these settings. Here I propose an alternative approach to tackle this problem through the textural study of high-pressure terrains that experienced dehydration reactions. Spatiotemporal evolution of dehydration reactions should be recorded during mineral nucleation and growth through variations in time and space of the reaction rate. Insights on the fluid migration mechanism could be inferred therefore by noting changes in the texture of prograde assemblages. The dehydration of antigorite in serpentinite is a perfect candidate to test this approach as it releases a significant amount of fluid and produces a concomitant porosity. Unusual alternation of equilibrium and disequilibrium textures observed in Cerro del Almirez (Betic Cordillera, S Spain)[1, 2] attest for a complex fluid migration pattern for one of the most relevant reactions in subduction zones

Haptoglobin genotyping of Vietnamese: global distribution of HP del, complete deletion allele of the HP gene.

PubMed

Soejima, Mikiko; Agusa, Tetsuro; Iwata, Hisato; Fujihara, Junko; Kunito, Takashi; Takeshita, Haruo; Lan, Vi Thi Mai; Minh, Tu Binh; Takahashi, Shin; Trang, Pham Thi Kim; Viet, Pham Hung; Tanabe, Shinsuke; Koda, Yoshiro

2015-01-01

The haptoglobin (HP) gene deletion allele (HP(del)) is responsible for anhaptoglobinemia and a genetic risk factor for anaphylaxis reaction after transfusion due to production of the anti-HP antibody. The distribution of this allele has been explored by several groups including ours. Here, we studied the frequency of HP(del) in addition to the distribution of common HP genotypes in 293 Vietnamese. The HP(del) was encountered with the frequency of 0.020. The present result suggested that this deletion allele is restricted to East and Southeast Asians. Thus, this allele seems to be a potential ancestry informative marker for these populations. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

CDC25AQ110del: A Novel Cell Division Cycle 25A Isoform Aberrantly Expressed in Non-Small Cell Lung Cancer

PubMed Central

Younis, Rania H.; Cao, Wei; Lin, Ruxian; Xia, Ronghui; Liu, Zhenqiu; Edelman, Martin J.; Mei, Yuping; Mao, Li; Ren, Hening

2012-01-01

Objective Lung cancer remains number one cause of cancer related deaths worldwide. Cell cycle deregulation plays a major role in the pathogenesis of Non-Small Cell Lung Cancer (NSCLC). CDC25A represents a critical cell cycle regulator that enhances cell cycle progression. In this study we aimed to investigate the role of a novel CDC25A transcriptional variant, CDC25AQ110del, on the regulation of the CDC25A protein, and its impact on prognosis of NSCLC patients. Methodology/Principal Findings Here we report a novel CDC25A transcript variant with codon 110 (Glutamine) deletion, that we termed CDC25AQ110del in NSCLC cells. In 9 (75%) of the 12 NSCLC cell lines, CDC25AQ110del expression accounted for more than 20% of the CDC25A transcripts. Biological effects of CDC25AQ110del were investigated in H1299 and HEK-293F cells using UV radiation, flowcytometry, cyclohexamide treatment, and confocal microscopy. Compared to CDC25Awt, CDC25AQ110del protein had longer half-life; cells expressing CDC25AQ110del were more resistant to UV irradiation and showed more mitotic activity. Taqman-PCR was used to quantify CDC25AQ110del expression levels in 88 primary NSCLC tumor/normal tissue pairs. In patients with NSCLC, Kaplan Meier curves showed tumors expressing higher levels of CDC25AQ110del relative to the adjacent lung tissues to have significantly inferior overall survival (P = .0018). Significance Here we identified CDC25AQ110del as a novel transcriptional variant of CDC25A in NSCLC. The sequence-specific nature of the abnormality could be a prognostic indicator in NSCLC patients as well as a candidate target for future therapeutic strategies. PMID:23071577

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

PubMed Central

Van Goor, Fredrick; Hadida, Sabine; Grootenhuis, Peter D. J.; Burton, Bill; Stack, Jeffrey H.; Straley, Kimberly S.; Decker, Caroline J.; Miller, Mark; McCartney, Jason; Olson, Eric R.; Wine, Jeffrey J.; Frizzell, Ray A.; Ashlock, Melissa; Negulescu, Paul A.

2011-01-01

Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that impair the function of CFTR, an epithelial chloride channel required for proper function of the lung, pancreas, and other organs. Most patients with CF carry the F508del CFTR mutation, which causes defective CFTR protein folding and processing in the endoplasmic reticulum, resulting in minimal amounts of CFTR at the cell surface. One strategy to treat these patients is to correct the processing of F508del-CFTR with small molecules. Here we describe the in vitro pharmacology of VX-809, a CFTR corrector that was advanced into clinical development for the treatment of CF. In cultured human bronchial epithelial cells isolated from patients with CF homozygous for F508del, VX-809 improved F508del-CFTR processing in the endoplasmic reticulum and enhanced chloride secretion to approximately 14% of non-CF human bronchial epithelial cells (EC50, 81 ± 19 nM), a level associated with mild CF in patients with less disruptive CFTR mutations. F508del-CFTR corrected by VX-809 exhibited biochemical and functional characteristics similar to normal CFTR, including biochemical susceptibility to proteolysis, residence time in the plasma membrane, and single-channel open probability. VX-809 was more efficacious and selective for CFTR than previously reported CFTR correctors. VX-809 represents a class of CFTR corrector that specifically addresses the underlying processing defect in F508del-CFTR. PMID:21976485

First trimester initiation of prenatal care in the US-Mexico border region.

PubMed

McDonald, Jill A; Argotsinger, Brittany; Mojarro, Octavio; Rochat, Roger; Amatya, Anup

2015-08-01

To systematically examine prevalence of first trimester prenatal care (FTPNC) in the 44 US counties and 80 Mexican municipios of the binational border region; and to describe disparities between border and nonborder areas within states, border states, and countries. We combined 2009 records of singleton live births from the 10 US-Mexico border states (N=1,370,206) into a single file. We included FTPNC; county/municipio, state, and country of maternal residence; and demographic variables common to all records. We computed prevalence of FTPNC for border and nonborder residents by state and country. Using multivariable regression, we computed adjusted prevalence ratios (aPR) for FTPNC in border relative to nonborder residents, states relative to one another, and the US relative to Mexico. In 2009, 68.8% of US-Mexico border mothers and 72.9% of nonborder mothers received FTPNC. After adjustment, nonborder residents had higher prevalence of FTPNC than border residents in Sonora, New Mexico, Arizona, Coahuila, and Chihuahua (aPR=1.09-124). In US states, prevalence was 13%-36% higher in New Mexico, Arizona, and California than Texas. In Mexico, when compared with Coahuila, adjusted prevalence was 12%-20% higher in neighboring states. Between countries, FTPNC prevalence in border counties/municipios was higher in Mexico among women with low parity/low education and in the United States among women with high parity/high education. In the US and Mexico, women in border counties/municipios receive less timely prenatal care than their nonborder counterparts, but the magnitude of the disparity varies by state. Lack of a consistent, binational approach to birth data collection requires cautious interpretation of findings.

DelPhi Web Server: A comprehensive online suite for electrostatic calculations of biological macromolecules and their complexes

PubMed Central

Sarkar, Subhra; Witham, Shawn; Zhang, Jie; Zhenirovskyy, Maxim; Rocchia, Walter; Alexov, Emil

2011-01-01

Here we report a web server, the DelPhi web server, which utilizes DelPhi program to calculate electrostatic energies and the corresponding electrostatic potential and ionic distributions, and dielectric map. The server provides extra services to fix structural defects, as missing atoms in the structural file and allows for generation of missing hydrogen atoms. The hydrogen placement and the corresponding DelPhi calculations can be done with user selected force field parameters being either Charmm22, Amber98 or OPLS. Upon completion of the calculations, the user is given option to download fixed and protonated structural file, together with the parameter and Delphi output files for further analysis. Utilizing Jmol viewer, the user can see the corresponding structural file, to manipulate it and to change the presentation. In addition, if the potential map is requested to be calculated, the potential can be mapped onto the molecule surface. The DelPhi web server is available from http://compbio.clemson.edu/delphi_webserver. PMID:24683424

Combined effects of VX-770 and VX-809 on several functional abnormalities of F508del-CFTR channels.

PubMed

Kopeikin, Z; Yuksek, Z; Yang, H-Y; Bompadre, S G

2014-09-01

The most common cystic fibrosis-associated mutation, the deletion of phenylalanine 508 (F508del), results in channels with poor membrane expression and impaired function. VX-770, a clinically approved drug for treatment of CF patients carrying the G551D mutation, and VX-809, a corrector shown in vitro to increase membrane expression of mutant channels, are currently undergoing clinical trials, but functional data at the molecular level is still lacking. The effect of VX-770 and VX-809 on the multiple functional defects of F508del-CFTR was assessed via excised inside-out patch-clamp experiments. VX-770 completely restores the low opening-rate of F508del-CFTR, with smaller open-time increase, in temperature-corrected and VX-809-treated channels. The shorter locked-open time of hydrolysis-deficient F508del-CFTR is also prolonged by VX-770. VX-809 does not improve channel function by itself as previously reported. The results from these studies can be interpreted as an equilibrium shift toward the open-channel conformation of F508del-CFTR channels. Copyright © 2014 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

[Bibliometric analysis of Revista Médica del IMSS in the Scopus database for the period between 2005-2013].

PubMed

García-Gómez, Francisco; Ramírez-Méndez, Fernando

2015-01-01

To analyze the number of articles of Revista Médica del Instituto Mexicano del Seguro Social (Rev Med Inst Mex Seguro Soc) in the Scopus database and describe principal quantitative bibliometric indicators of scientific publications during the period between 2005 to 2013. Scopus database was used limited to the period between 2005 to 2013. The analysis cover mainly title of articles with the title of Revista Médica del Instituto Mexicano del Seguro Social and its possible modifications. For the analysis, Scopus, Excel and Access were used. 864 articles were published during the period between 2005 to 2013 in the Scopus database. We identified authors with the highest number of contributions including articles with the highest citation rate and forms of documents cited. We also divided articles by subjects, types of documents and other bibliometric indicators which characterize the publications. The use of Scopus brings the possibility of analyze with an external tool the visibility of the scientific production published in the Revista Médica del IMSS. The use of this database also contributes to identify the state of science in México, as well as in the developing countries.

An InSAR-based survey of volcanic deformation in the central Andes

NASA Astrophysics Data System (ADS)

Pritchard, M. E.; Simons, M.

2004-02-01

We extend an earlier interferometric synthetic aperture radar (InSAR) survey covering about 900 remote volcanos of the central Andes (14°-27°S) between the years 1992 and 2002. Our survey reveals broad (10s of km), roughly axisymmetric deformation at 4 volcanic centers: two stratovolcanoes are inflating (Uturuncu, Bolivia, and Hualca Hualca, Peru); another source of inflation on the border between Chile and Argentina is not obviously associated with a volcanic edifice (here called Lazufre); and a caldera (Cerro Blanco, also called Robledo) in northwest Argentina is subsiding. We explore the range of source depths and volumes allowed by our observations, using spherical, ellipsoidal and crack-like source geometries. We further examine the effects of local topography upon the deformation field and invert for a spherical point-source in both elastic half-space and layered-space crustal models. We use a global search algorithm, with gradient search methods used to further constrain best-fitting models. Inferred source depths are model-dependent, with differences in the assumed source geometry generating a larger range of accepted depths than variations in elastic structure. Source depths relative to sea level are: 8-18 km at Hualca Hualca; 12-25 km for Uturuncu; 5-13 km for Lazufre, and 5-10 km at Cerro Blanco. Deformation at all four volcanoes seems to be time-dependent, and only Uturuncu and Cerro Blanco were deforming during the entire time period of observation. Inflation at Hualca Hualca stopped in 1997, perhaps related to a large eruption of nearby Sabancaya volcano in May 1997, although there is no obvious relation between the rate of deformation and the eruptions of Sabancaya. We do not observe any deformation associated with eruptions of Lascar, Chile, at 16 other volcanoes that had recent small eruptions or fumarolic activity, or associated with a short-lived thermal anomaly at Chiliques volcano. We posit a hydrothermal system at Cerro Blanco to explain the

Reconversion Militar del Ejercito en la Frontera Dominico-Haitiana (Military Restructuring of the Army on the Dominican-Haitian Border)

DTIC Science & Technology

2013-05-22

Estado Mayor del Ejército de EE. UU. en cumplimiento parcial de los requisitos para la obtención del grado de MAESTRÍA EN CIENCIAS Y ARTES...MILITARES Estudios Generales Por MAYOR FELIPE CÉSPEDES TEJERA, EJÉRCITO NACIONAL DOMINICANO Licenciado en Ciencias Sociales, Universidad...ANSI Std. Z39.18 ii MAESTRÍA EN ARTES Y CIENCIAS MILITARES PÁGINA DE APROBACIÓN DE LA TESIS Nombre del Candidato: Mayor Felipe Céspedes Tejera

Characterization of nasal potential difference in cftr knockout and F508del-CFTR mice.

PubMed

Saussereau, Emilie Lyne; Roussel, Delphine; Diallo, Siradiou; Debarbieux, Laurent; Edelman, Aleksander; Sermet-Gaudelus, Isabelle

2013-01-01

Treatments designed to correct cystic fibrosis transmembrane conductance regulator (CFTR) defects must first be evaluated in preclinical experiments in the mouse model of cystic fibrosis (CF). Mice nasal mucosa mimics the bioelectric defect seen in humans. The use of nasal potential difference (V(TE)) to assess ionic transport is a powerful test evaluating the restoration of CFTR function. Nasal V(TE) in CF mice must be well characterized for correct interpretation. We performed V(TE) measurements in large-scale studies of two mouse models of CF--B6;129 cftr knockout and FVB F508del-CFTR--and their respective wild-type (WT) littermates. We assessed the repeatability of the test for cftr knockout mice and defined cutoff points distinguishing between WT and F508del-CFTR mice. We determined the typical V(TE) values for CF and WT mice and demonstrated the existence of residual CFTR activity in F508del-CFTR mice. We characterized intra-animal variability in B6;129 mice and defined the cutoff points for F508del-CFTR chloride secretion rescue. Hyperpolarization of more than -2.15 mV after perfusion with a low-concentration Cl(-) solution was considered to indicate a normal response. These data will make it possible to interpret changes in nasal V(TE) in mouse models of CF, in future preclinical studies.

Forensic efficiency and genetic variation of 30 InDels in Vietnamese and Nigerian populations.

PubMed

Du, Weian; Peng, Zhiyong; Feng, Chunlei; Zhu, Bofeng; Wang, Bangchao; Wang, Yue; Liu, Chao; Chen, Ling

2017-10-24

Insertion/deletion polymorphisms (InDels) are ubiquitous diallelic genetic markers that have drawn increasing attention from forensic researchers. Here, we investigated 30 InDel loci in Vietnamese and Nigerian populations and evaluated their usefulness in forensic genetics. The polymorphic information content of these populations ranged, respectively, from 0.164 to 0.375 and from 0.090 to 0.375 across loci. After Bonferroni correction, no significant deviation from Hardy-Weinberg equilibrium was found, except for HLD97 in the Nigerian population. The cumulative power of exclusion for all 30 loci in the Vietnamese and Nigerian populations was 0.9870 and 0.9676, respectively, indicating that this InDel set is not suitable for paternity testing in these populations, but could be included as a supplement. For the Vietnamese and the Nigerian populations, the mean observed heterozygosity was 0.5917 and 0.6268, and the combined discrimination power of the 30 loci was 0.9999999999767 and 0.9999999999603, respectively. These findings indicated that these InDels may be suitable for personal forensic identification in the studied populations. The results of D A distance, phylogenetic tree, principal component, and cluster analyses were consistent and indicated a clear pattern of regional distribution. Moreover, the Vietnamese population was shown to have close genetic relationships with the Guangdong Han and Shanghai Han populations.

Forensic efficiency and genetic variation of 30 InDels in Vietnamese and Nigerian populations

PubMed Central

Du, Weian; Peng, Zhiyong; Feng, Chunlei; Zhu, Bofeng; Wang, Bangchao; Wang, Yue; Liu, Chao; Chen, Ling

2017-01-01

Insertion/deletion polymorphisms (InDels) are ubiquitous diallelic genetic markers that have drawn increasing attention from forensic researchers. Here, we investigated 30 InDel loci in Vietnamese and Nigerian populations and evaluated their usefulness in forensic genetics. The polymorphic information content of these populations ranged, respectively, from 0.164 to 0.375 and from 0.090 to 0.375 across loci. After Bonferroni correction, no significant deviation from Hardy-Weinberg equilibrium was found, except for HLD97 in the Nigerian population. The cumulative power of exclusion for all 30 loci in the Vietnamese and Nigerian populations was 0.9870 and 0.9676, respectively, indicating that this InDel set is not suitable for paternity testing in these populations, but could be included as a supplement. For the Vietnamese and the Nigerian populations, the mean observed heterozygosity was 0.5917 and 0.6268, and the combined discrimination power of the 30 loci was 0.9999999999767 and 0.9999999999603, respectively. These findings indicated that these InDels may be suitable for personal forensic identification in the studied populations. The results of DA distance, phylogenetic tree, principal component, and cluster analyses were consistent and indicated a clear pattern of regional distribution. Moreover, the Vietnamese population was shown to have close genetic relationships with the Guangdong Han and Shanghai Han populations. PMID:29179488

Extracorporeal membrane oxygenation in children with heart disease and del22q11 syndrome: a review of the Extracorporeal Life Support Organization Registry.

PubMed

Prodhan, P; Gossett, J M; Rycus, P T; Gupta, P

2015-11-01

The study objective was to evaluate outcomes among children with del22q11 (DiGeorge) syndrome supported on ECMO for heart disease. The ELSO registry database was queried to include all children <18 years undergoing heart surgery for either common atrio-ventricular canal, tetralogy of Fallot, truncus arteriosus or transposition of the great vessels and interrupted aortic arch and requiring ECMO, from 1998-2011. The outcomes evaluated included mortality, ECMO duration and length of hospital stay in patients with del22q11 syndrome and with no del22q11 syndrome. Eighty-eight ECMO runs occurred in children with del22q11 syndrome while 2694 ECMO runs occurred in children without del22q11 syndrome. For patients with heart defects receiving ECMO, del22q11 syndrome did not confer a significant mortality risk or an increased risk of infectious complications before or while on ECMO support. Neither the duration of ECMO nor mechanical ventilation prior to ECMO deployment were prolonged in patients with del22q11 syndrome compared to the controls. © The Author(s) 2015.

Developing market class specific InDel markers from next generation sequence data in Phaseolus vulgaris L.

PubMed

Moghaddam, Samira Mafi; Song, Qijian; Mamidi, Sujan; Schmutz, Jeremy; Lee, Rian; Cregan, Perry; Osorno, Juan M; McClean, Phillip E

2014-01-01

Next generation sequence data provides valuable information and tools for genetic and genomic research and offers new insights useful for marker development. This data is useful for the design of accurate and user-friendly molecular tools. Common bean (Phaseolus vulgaris L.) is a diverse crop in which separate domestication events happened in each gene pool followed by race and market class diversification that has resulted in different morphological characteristics in each commercial market class. This has led to essentially independent breeding programs within each market class which in turn has resulted in limited within market class sequence variation. Sequence data from selected genotypes of five bean market classes (pinto, black, navy, and light and dark red kidney) were used to develop InDel-based markers specific to each market class. Design of the InDel markers was conducted through a combination of assembly, alignment and primer design software using 1.6× to 5.1× coverage of Illumina GAII sequence data for each of the selected genotypes. The procedure we developed for primer design is fast, accurate, less error prone, and higher throughput than when they are designed manually. All InDel markers are easy to run and score with no need for PCR optimization. A total of 2687 InDel markers distributed across the genome were developed. To highlight their usefulness, they were employed to construct a phylogenetic tree and a genetic map, showing that InDel markers are reliable, simple, and accurate.

Developing market class specific InDel markers from next generation sequence data in Phaseolus vulgaris L.

PubMed Central

Moghaddam, Samira Mafi; Song, Qijian; Mamidi, Sujan; Schmutz, Jeremy; Lee, Rian; Cregan, Perry; Osorno, Juan M.; McClean, Phillip E.

2013-01-01

Next generation sequence data provides valuable information and tools for genetic and genomic research and offers new insights useful for marker development. This data is useful for the design of accurate and user-friendly molecular tools. Common bean (Phaseolus vulgaris L.) is a diverse crop in which separate domestication events happened in each gene pool followed by race and market class diversification that has resulted in different morphological characteristics in each commercial market class. This has led to essentially independent breeding programs within each market class which in turn has resulted in limited within market class sequence variation. Sequence data from selected genotypes of five bean market classes (pinto, black, navy, and light and dark red kidney) were used to develop InDel-based markers specific to each market class. Design of the InDel markers was conducted through a combination of assembly, alignment and primer design software using 1.6× to 5.1× coverage of Illumina GAII sequence data for each of the selected genotypes. The procedure we developed for primer design is fast, accurate, less error prone, and higher throughput than when they are designed manually. All InDel markers are easy to run and score with no need for PCR optimization. A total of 2687 InDel markers distributed across the genome were developed. To highlight their usefulness, they were employed to construct a phylogenetic tree and a genetic map, showing that InDel markers are reliable, simple, and accurate. PMID:24860578

78 FR 30268 - Del Norte County Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

... Schools and Community Self-Determination Act (Pub. L. 112-141) (the Act) and operates in compliance with... to review prior year project's progress. Should the Secure Rural Schools Act be reauthorized, the.... ADDRESSES: The meetings will be held at the Del Norte County Unified School District, Redwood Room, 301 West...

Casimir force in the Gödel space-time and its possible induced cosmological inhomogeneity

NASA Astrophysics Data System (ADS)

Khodabakhshi, Sh.; Shojai, A.

2017-07-01

The Casimir force between two parallel plates in the Gödel universe is computed for a scalar field at finite temperature. It is observed that when the plates' separation is comparable with the scale given by the rotation of the space-time, the force becomes repulsive and then approaches zero. Since it has been shown previously that the universe may experience a Gödel phase for a small period of time, the induced inhomogeneities from the Casimir force are also studied.

Combination of t(4;14), del(17p13), del(1p32) and 1q21 gain FISH probes identifies clonal heterogeneity and enhances the detection of adverse cytogenetic profiles in 233 newly diagnosed multiple myeloma.

PubMed

Smol, Thomas; Dufour, Annika; Tricot, Sabine; Wemeau, Mathieu; Stalnikiewicz, Laure; Bernardi, Franck; Terré, Christine; Ducourneau, Benoît; Bisiau, Hervé; Daudignon, Agnès

2017-01-01

Our aim was to set the FISH combination of del(17p13), t(4;14), 1q21 gain and del(1p32), four adverse cytogenetic factors rarely evaluated together, and compare our technical thresholds with those defined in the literature. Two hundred thirty-three patients with MM at diagnosis were studied using FISH to target 4 unfavorable cytogenetic abnormalities: 17p13 deletion, t(4;14) translocation, 1p32 deletion and 1q21 gain. Technical thresholds were determined for each probe using isolated CD138-expressing PC from patients without MM. The FISH analysis identified abnormalities in 79.0% of patients. Del(17p13) was detected in 15.0% of cases, t(4;14) in 11.5%, 1q21 gain in 37.8% and del(1p32) in 8.7%. Adding 1p32/1q21 FISH probes has enabled us to identify adverse cytogenetic profiles in 39.0% of patients without del(17p13) or t(4;14). Clonal heterogeneity was observed in 51.1% of patients as well as an increase in the number of adverse abnormalities when related clones were greater than or equal to 2 (85.1% against 45.6%). FISH allowed detecting accumulation of adverse abnormalities and clonal heterogeneity in MM with a combination of 4 probes. The impacts of these two parameters need to be evaluated, and could be included in future cytogenetic classifications.

El diseño final del espectrógrafo de banco (EBASIM) para CASLEO

NASA Astrophysics Data System (ADS)

Simmons, J.; Levato, H.

Utilizando el código de óptica ACCOS V se ha finalizado el diseño del espectrógrafo de banco para CASLEO. En una comunicación anterior habíamos indicado que utilizaríamos un colimador de 150 mm de diámetro con un radio de curvatura de 1540 mm. Para el espejo cámara, que tiene un diámetro de 200 mm, el radio de curvatura es de 1200 mm, ambos radios con una tolerancia no mayor a los 3 mm. En la presente, se informa sobre los detalles finales del cálculo del espectrógrafo que incluye el cómputo para 5 longitudes de onda diferentes y alrededor de 100 rayos. En todos los casos el 75 % de energía está dentro de un diámetro de 13 micrones. El diseño ha sido probado entre 3500 Å hasta 9000 Å con resultados satisfactorios.

[Effectiveness of azacitidine in chronic myelomonocytic leukemia harboring del(20q) - a case report].

PubMed

Manabe, Masahiro; Okita, Junya; Takakuwa, Teruhito; Harada, Naonori; Aoyama, Yasutaka; Kumura, Takeo; Ohta, Tadanobu; Furukawa, Yoshio; Mugitani, Atsuko

2014-06-01

A 7 1-year-old man was admitted to our hospital with leukocytosis and anemia. Chronic myelomonocytic leukemia (CMML)harboring del(20q)was diagnosed by peripheral blood examination and bone marrow aspiration. The patient was subsequently treated with azacitidine, which resulted in rapid disappearance of monocytosis and resolved his dependency on red cell transfusion. With regard to the chromosomal abnormality, although del(20q)is estimated to be encountered in approximately 0.7-1.0% of all CMML cases, its significance in prognosis has not been fully analyzed. Hence, more such cases need to be evaluated to elucidate the therapeutic outcome of CMML involving del(20q). In addition, the Wilms tumor-1(WT 1)level in the patient gradually decreased after the initiation of azacitidine therapy. This phenomenon of WT1 decrease synchronizing with the patient's clinical improvement might reflect therapeutic efficacy with regard to the clinical course, as had been observed in acute myeloid leukemia and myelodysplastic syndrome.

DELIVERING TIMELY AIR QUALITY, TRAFFIC, AND WEATHER INFORMATION TO YOUR COMMUNITY/THE PASO DEL NORTE ENVIRONMENTAL MONITORING PROJECT

EPA Science Inventory

EPA has developed a technology transfer handbook for the EMPACT Paso del Norte Project. The EMPACT Paso del Norte Environmental Monitoring Project is a mobile vehicle emissions project that involves the international community of El Paso, TX; Sundland Park, NM; and Juarez, Mexico...

Faculty Activity Analysis in the Universidad Tecnica Del Estado Campuses.

ERIC Educational Resources Information Center

Karadima, Oscar

An analysis of academic activities of college faculty at the eight campuses of Chile's Universidad Tecnica del Estado was conducted. Activities were grouped into seven categories: direct teaching, indirect teaching, research, community services, faculty development, academic administration, and other activities. Following the narrative…

Lack of effect of the alpha2C-adrenoceptor Del322-325 polymorphism on inhibition of cyclic AMP production in HEK293 cells.

PubMed

Montgomery, M D; Bylund, D B

2010-02-01

The alpha(2C)-adrenoceptor has multiple functions, including inhibiting release of noradrenaline from presynaptic nerve terminals. A human alpha(2C) polymorphism, Del322-325, a potential risk factor for heart failure, has been reported to exhibit reduced signalling in CHO cells. To further understand the role of the Del322-325 polymorphism on receptor signalling, we attempted to replicate and further study the reduced signalling in HEK293 cells. Human alpha(2C) wild-type (WT) and Del322-325 adrenoceptors were stably transfected into HEK293 cells. Radioligand binding was performed to determine affinities for both receptors. In intact cells, inhibition of forskolin-stimulated cyclic AMP production by WT and Del322-325 clones with a range of receptor densities (200-2320 fmol.mg(-1) protein) was measured following agonist treatment. Noradrenaline, brimonidine and clonidine exhibited similar binding affinities for WT and Del322-325. Brimonidine and clonidine also had similar efficacies and potencies for both receptors for the inhibition of cyclic AMP production at all receptor densities tested. A linear regression analysis comparing efficacy and potency with receptor expression levels showed no differences in slopes between WT and Del322-325. The alpha(2C) WT and Del322-325 adrenoceptors exhibited similar binding properties. Additionally, inhibition of cyclic AMP production by Del322-325 was similar to that of WT over a range of receptor densities. Therefore, in intact HEK293 cells, the alpha(2C)-Del322-325 polymorphism does not exhibit reduced signalling to adenylyl cyclase and may not represent a clinically important phenotype.

[Trattamento farmacologico del disturbo da uso di alcol. Evidenze scientifiche].

PubMed

Attilia, Fabio; Perciballi, Roberta; Rotondo, Claudia; Capriglione, Ida; Iannuzzi, Silvia; Attilia, Maria Luisa; Vitali, Mario; Alessandrini, Giovanni; Scamporrino, Maria Concetta Marcella; Fiore, Marco; Ceccanti, Mauro

2018-01-01

RIASSUNTO. La terapia farmacologica nei pazienti con disturbo da uso di alcol riveste un ruolo centrale nel progetto terapeutico, altamente contestualizzato in un approccio multidisciplinare. Sebbene i trattamenti non farmacologici per la dipendenza da alcol risultino ben strutturati e in continua evoluzione, dal punto di vista medico le possibilità di intervento sono realmente ristrette, con poche molecole a disposizione approvate per il disturbo da uso di alcol: nello specifico, l'acamprostato, il naltrexone e, più recentemente, il nalmefene tra gli anticraving; il disulfiram tra gli avversivanti. Nuovi approcci sperimentali stanno cercando di ampliare tale gamma attraverso l'utilizzo di farmaci off-label. Evidenze scientifiche devono supportare l'indicazione terapeutica, quest'ultima deve dimostrarsi "cucita" sulle esigenze del paziente e sulle comorbilità presenti tenendo conto del profilo bio-psico-sociale individuale. Fondamentale risulta il follow-up per valutare la ritenzione in trattamento e il monitoraggio degli outcome alcologici.

Pío del Río Hortega and the discovery of the oligodendrocytes

PubMed Central

Pérez-Cerdá, Fernando; Sánchez-Gómez, María Victoria; Matute, Carlos

2015-01-01

Pío del Río Hortega (1882–1945) discovered microglia and oligodendrocytes (OLGs), and after Ramón y Cajal, was the most prominent figure of the Spanish school of neurology. He began his scientific career with Nicolás Achúcarro from whom he learned the use of metallic impregnation techniques suitable to study non-neuronal cells. Later on, he joined Cajal’s laboratory. and Subsequently, he created his own group, where he continued to develop other innovative modifications of silver staining methods that revolutionized the study of glial cells a century ago. He was also interested in neuropathology and became a leading authority on Central Nervous System (CNS) tumors. In parallel to this clinical activity, del Río Hortega rendered the first systematic description of a major polymorphism present in a subtype of macroglial cells that he named as oligodendroglia and later OLGs. He established their ectodermal origin and suggested that they built the myelin sheath of CNS axons, just as Schwann cells did in the periphery. Notably, he also suggested the trophic role of OLGs for neuronal functionality, an idea that has been substantiated in the last few years. Del Río Hortega became internationally recognized and established an important neurohistological school with outstanding pupils from Spain and abroad, which nearly disappeared after his exile due to the Spanish civil war. Yet, the difficulty of metal impregnation methods and their variability in results, delayed for some decades the confirmation of his great insights into oligodendrocyte biology until the development of electron microscopy and immunohistochemistry. This review aims at summarizing the pioneer and essential contributions of del Río Hortega to the current knowledge of oligodendrocyte structure and function, and to provide a hint of the scientific personality of this extraordinary and insufficiently recognized man. PMID:26217196

CHEK2*1100delC Variant and BRCA1/2-Negative Familial Breast Cancer - A Family-Based Genetic Association Study

DTIC Science & Technology

2007-10-01

AD_________________ Award Number: DAMD17-03-1-0774 TITLE: CHEK2 *1100delC Variant and BRCA1/2...NUMBER CHEK2 *1100delC Variant and BRCA1/2-Negative Familial Breast Cancer - A Family- Based Genetic Association Study 5b. GRANT NUMBER DAMD17...association between the CHEK2 *1100delC gene variant and breast cancer among BRCA1/2-negative families. Vital to DNA replication and normal growth of breast

The Cuernos del Paine mountains in Torres del Paine National Park in Chile provide a backdrop to a herd of guanacos during NASA's AirSAR 2004 campaign

NASA Image and Video Library

2004-03-11

The Cuernos del Paine mountains in Torres del Paine National Park in Chile provide a backdrop to a herd of guanacos during NASA's AirSAR 2004 campaign. AirSAR 2004 is a three-week expedition in Central and South America by an international team of scientists that is using an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR), located onboard NASA's DC-8 airborne laboratory. Scientists from many parts of the world are combining ground research with NASA's AirSAR technology to improve and expand on the quality of research they are able to conduct. Founded in 1959, Torres del Paine National Park encompasses 450,000 acres in the Patagonia region of Chile. This region is being studied by NASA using a DC-8 equipped with an Airborne Synthetic Aperture Radar (AirSAR) developed by scientists from NASA’s Jet Propulsion Laboratory. This is a very sensitive region that is important to scientists because the temperature has been consistently rising causing a subsequent melting of the region’s glaciers. AirSAR will provide a baseline model and unprecedented mapping of the region. This data will make it possible to determine whether the warming trend is slowing, continuing or accelerating. AirSAR will also provide reliable information on ice shelf thickness to measure the contribution of the glaciers to sea level.

Generalized Gödel universes in higher dimensions and pure Lovelock gravity

NASA Astrophysics Data System (ADS)

Dadhich, Naresh; Molina, Alfred; Pons, Josep M.

2017-10-01

The Gödel universe is a homogeneous rotating dust with negative Λ which is a direct product of a three-dimensional pure rotation metric with a line. We would generalize it to higher dimensions for Einstein and pure Lovelock gravity with only one N th-order term. For higher-dimensional generalization, we have to include more rotations in the metric, and hence we shall begin with the corresponding pure rotation odd (d =2 n +1 )-dimensional metric involving n rotations, which eventually can be extended by a direct product with a line or a space of constant curvature for yielding a higher-dimensional Gödel universe. The considerations of n rotations and also of constant curvature spaces is a new line of generalization and is being considered for the first time.

The effect of the common c.2299delG mutation in USH2A on RNA splicing.

PubMed

Lenassi, Eva; Saihan, Zubin; Bitner-Glindzicz, Maria; Webster, Andrew R

2014-05-01

Recessive variants in the USH2A gene are an important cause of both Usher syndrome and nonsyndromic retinitis pigmentosa. A single base-pair deletion in exon 13 (c.2299delG, p.Glu767Serfs*21) is considered the most frequent mutation of USH2A. It is predicted to generate a premature termination codon and is presumed to lead to nonsense mediated decay. However the effect of this variant on RNA has not been formally investigated. It is not uncommon for exonic sequence alterations to cause aberrant splicing and the aim of the present report is to evaluate the effect of c.2299delG on USH2A transcripts. Nasal cells represent the simplest available tissue to study splicing defects in USH2A. Nasal brushing, RNA extraction from nasal epithelial cells and reverse transcription PCR were performed in five Usher syndrome patients who were homozygous for c.2299delG, two unaffected c.2299delG heterozygotes and seven control individuals. Primers to amplify between exons 12 and 15 and exons 10 and 14 were utilised. Significant variability was observed between different RT-PCR experiments. Importantly, in controls, PCR product of the expected size were amplified on all occasions (13/13 experiments); for patients this was true in only 4/14 experiments (Fisher exact test p = 0.0002). Bioinformatics tools predict the c.2299delG change to disrupt an exonic splicing enhancer and to create an exonic splicing silencer within exon 13. Here, we report an effect of the common c.2299delG mutation on splicing of exons 12 and 13 of USH2A. Future studies are expected to provide important insights into the contribution of this effect on the phenotype. Copyright © 2014 Elsevier Ltd. All rights reserved.

Cosmogenic Radionuclides in the Campo Del Cielo Iron Meteorite

NASA Technical Reports Server (NTRS)

Liberman, R. G.; FernandezNiello, J. O.; Reedy, R. C.; Fifield, L. K.; diTada, M. L.

2001-01-01

Cosmogenic Be-10, Al-26, Cl-36, Ca-41, and Ni-59 were measured in the Campo del Cielo iron meteorite. Our results led us to conclude that the pre-atmospheric radius might have been approximately 2 m. Comparisons with other big bodies are also presented. Additional information is contained in the original extended abstract.

KEGS Discovery of 28 Supernova Candidates in the K2 Campaign 17 Field with DECam

NASA Astrophysics Data System (ADS)

Narayan, G.; Rest, A.; Strampelli, G. M.; Zenteno, A.; James, D. J.; Smith, R. C.; Tucker, B. E.; Garnavich, P.; Margheim, S.; Kasen, D.; Olling, R.; Shaya, E.; Buron, F. Forster; Villar, V. A.

2018-05-01

The Kepler Extra-Galactic Survey (KEGS, see http://www.mso.anu.edu.au/kegs/ ) reports the discovery of 28 supernova candidates with the Dark Energy Camera (DECam, NOAO 2017B-0285) on the 4m Blanco Telescope at Cerro Tololo Inter-American Observatory (CTIO).

Prevalence of 2314delG mutation in Spanish patients with Usher syndrome type II (USH2).

PubMed

Beneyto, M M; Cuevas, J M; Millán, J M; Espinós, C; Mateu, E; González-Cabo, P; Baiget, M; Doménech, M; Bernal, S; Ayuso, C; García-Sandoval, B; Trujillo, M J; Borrego, S; Antiñolo, G; Carballo, M; Nájera, C

2000-06-01

The Usher syndrome (USH) is a group of autosomal recessive diseases characterized by congenital sensorineural hearing loss and retinitis pigmentosa. Three clinically distinct forms of Usher syndrome have so far been recognized and can be distinguished from one another by assessing auditory and vestibular function. Usher syndrome type II (USH2) patients have congenital moderate-to-severe nonprogressive hearing loss, retinitis pigmentosa, and normal vestibular function. Genetic linkage studies have revealed genetic heterogeneity among the three types of USH, with the majority of USH2 families showing linkage to the USH2A locus in 1q41. The USH2A gene (MIM 276901) has been identified: three mutations, 2314delG, 2913delG, and 4353-54delC, were initially reported in USH2A patients, the most frequent of which is the 2314delG mutation. It has been reported that this mutation can give rise to typical and atypical USH2 phenotypes. USH2 cases represent 62% of all USH cases in the Spanish population, and 95% of these cases have provided evidence of linkage to the USH2A locus. In the present study, the three reported mutations were analyzed in 59 Spanish families with a diagnosis of USH type II. The 2314delG was the only mutation identified in our population: it was detected in 25% of families and 16% of USH2 chromosomes analyzed. This study attempts to estimate the prevalence of this common mutation in a homogeneous Spanish population.

An experiment of formation of charmoni states in annihilation P-Pbarra. Un esperimento di formazione di stati del charmonio in annichilazione P-Pbarra (in Italian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pallavicini, Marco

1995-01-01

Oggetto di questa tesi e la misura di alcune caratteristiche fisiche (massa, larghezza, e larghezza parziale in p -more » $$\\bar{p}$$) degli stati 3P 1 e 3P 2 del charmonio, -ovvero del sistema legato di un quark "charm" e del suo antiquark-, nell'amito dell'esperimento E-760, installato nell'accumulatore di antiprotoni del Fermilab.« less

Segundo Catálogo Estelar del Hemisferio Sur con Astrolabio Fotoeléctrico PAII

NASA Astrophysics Data System (ADS)

Manrique, W. T.; Podestá, R. C.; Alonso, E.; Actis, E. V.; Pacheco, A. M.; Bustos, G.; Lizhi, L.; Zezhi, W.; Fanmiao, Z.; Hongqi, W.; Perdomo, R.

Recordamos que entre el Observatorio Astronómico ``Félix Aguilar'', el Observatorio Astronómico de Beijing y el Observatorio Astronómico de La Plata, se ha convenido en desarrollar un Proyecto de Investigación conjunto, para la observación sistemática de estrellas en el Hemisferio Sur, con el objeto de la elaboración de un Catálogo Estelar Global utilizando un Astrolabio Fotoeléctrico PAII del Observatorio de Beijing, que ha sido usado con éxito en la República de China. En este trabajo se presenta el Segundo Catálogo Estelar del Hemisferio Sur, derivado de las observaciones realizadas con el PAII instalado en el OAFA, durante el períiodo Febrero de 1992 a Marzo de 1997. En este lapso se han observado mas de 400000 pasajes estelares, obteniéndose las correcciones Δ α y Δ δ de 5241 estrellas del FK4, FK5, FK5 Ext., SRS, CAMC y GC. Las precisiones medias son del orden de ± 3,2 ms en ascensión recta y ±0."057 en declinación. Rango de magnitudes : 2,0 a 11,5 Rango de declinaciones : -3o a -60o Epoca Media : 1994.9 Se analizan los residuos en función de la magnitud y tipo espectral, correcciones de grupo y frecuencia de distribución Δ α y Δ δ.

Temperature distribution in the Cerro Prieto geothermal field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Castillo B, F.; Bermejo M, F.J.; Domiguez A, B.

1981-01-01

A series of temperature and pressure logs and flow rate measurements was compiled for each of the geothermal wells drilled to different reservoir depths between October 1979 and December 1980. Based on the valuable information obtained, a series of graphs showing the thermal characteristics of the reservoir were prepared. These graphs clearly show the temperature distribution resulting from the movement of fluids from the deep regions toward the higher zones of the reservoir, thus establishing more reliable parameters for locating new wells with better production zones. Updated information based on data from new deep wells drilled in the geothermal fieldmore » is presented here. This new information does not differ much from earlier estimates and theories. However, the influence of faulting and fracturing on the hydrothermal recharge of the geothermal reservoir is seen more clearly.« less

Magnetotelluric studies at the Cerro Prieto geothermal field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goubau, W.M.; Goldstein, N.E.; Clarke, J.

During three years of magnetotelluric surveying, data were acquired at 26 sites distributed over 190 km/sup 2/ around the production area. A relatively well-defined strike of N27W +- 1.5/sup 0/ (magnetic) was established. The simple model shown suggests a lateral discontinuity in the vicinity of Nueva Leon.

Interdisciplinary Unit: La Isla del Encanto (The Enchanted Island).

ERIC Educational Resources Information Center

Ford-Guerrera, Rebecca

This document presents a series of 14 lesson plans in an interdisciplinary Spanish unit on "La isla del encanto/The Enchanted Island." The materials were prepared for students in grades 5 or 6 who have had basic Spanish instruction in previous grades. The students should also be familiar with basic concepts in English such as math…

Association of methylenetetrahydrofolate reductase (MTHFR 677C>T) and thymidylate synthase (TSER and TS 1494del6) polymorphisms with premature ovarian failure in Korean women.

PubMed

Rah, HyungChul; Jeon, Young Joo; Choi, Youngsok; Shim, Sung Han; Yoon, Tae Ki; Choi, Dong Hee; Cha, Sun Hee; Kim, Nam Keun

2012-11-01

The aim of our study was to investigate whether methylenetetrahydrofolate reductase (MTHFR) gene variant (MTHFR 677C>T) and thymidylate synthase (TS) gene variants (TS enhancer region [TSER] and TS 1494del6) confer a risk for premature ovarian failure (POF). We genotyped 136 POF patients and 236 controls among Korean women for the three single nucleotide polymorphism sites using polymerase chain reaction restriction fragment length polymorphism analysis. Differences in the MTHFR 677C>T, TSER, and TS 1494del6 genotype frequencies between POF patients and controls were compared, and odds ratios (ORs) and 95% CIs were determined as a measure of the strength of the association between genotypes and POF. The MTHFR 677CT and CT + TT variant genotypes were more frequent in POF patients than in controls (OR, 2.249; 95% CI, 1.317-3.843; and OR, 2.132; 95% CI, 1.268-3.585, respectively). The combined genotype frequencies of MTHFR 677CT + TT/TSER 3R3R and 677CT + TT/TS 1494del6 del6/del6 were higher in patients than in controls (OR, 2.300; 95% CI, 1.219-4.337; and OR, 3.314; 95% CI, 1.623-6.767, respectively). The T-3R-del6 and T-2R-del6 (MTHFR 677C>T/TSER/TS 1494del6) haplotypes were more frequent in patients (OR, 1.450; 95% CI, 1.050-2.002; and OR, 2.911; 95% CI, 1.191-7.117, respectively), whereas the C-2R-del6 haplotype was less frequent in patients (OR, 0.372; 95% CI, 0.152-0.912). The T-del6 (MTHFR 677/TS 1494del6) haplotype frequency was higher among patients (OR, 1.653; 95% CI, 1.206-2.266), whereas the C-del6 haplotype frequency was lower among patients (OR, 0.700; 95% CI, 0.516-0.950). We did not find an association between TSER or TS 1494del6 polymorphisms and POF. Our data suggest that the MTHFR 677T allele may increase the risk for POF, which could lead to the development of novel genetic markers for predicting the risk of POF in patients.

Prevalencia y tamizaje del Trastorno por Déficit de Atención con Hiperactividad en Costa Rica

PubMed Central

Weiss, Nicholas T.; Schuler, Jovita; Monge, Silvia; McGough, James J.; Chavira, Denise; Bagnarello, Monica; Herrera, Luis Diego; Mathews, Carol A.

2015-01-01

Resumen La investigación tuvo como propósito estimar la prevalencia del Trastorno por Déficit de Atención con Hiperactividad (TDAH) en Costa Rica y determinar si la versión en español del cuestionario Swanson Nolan and Pelham Scale IV (SNAP-IV) es un instrumento de tamizaje útil en una población de niños y niñas escolares costarricenses. El instrumento fue entregado a padres y maestros de 425 niños entre 5 y 13 años de edad (promedio = 8.8). Todos fueron evaluados con el instrumento Swanson, Kotkin, Agler, M-Flynn and Pelham Scale (SKAMP). Su diagnóstico fue confirmado con una entrevista clínica. La sensibilidad y la especificidad del SNAP-IV fueron evaluadas como predictores de criterios de diagnóstico según el DSM-IV. La prevalencia puntual en la muestra del TDAH fue del 5%. El tamizaje más preciso lo hizo el SNAP-IV completado por el maestro en un corte de 20%, con una sensibilidad de 96% y una especificidad de un 82%. La sensibilidad de los instrumentos completados por los padres fue más baja que aquella de los maestros. El SNAP-IV completado por las maestras con un corte aislando el 20% de los mayores puntajes categorizó correctamente a un 87% de los sujetos. PMID:22432094

Systematically frameshifting by deletion of every 4th or 4th and 5th nucleotides during mitochondrial transcription: RNA self-hybridization regulates delRNA expression.

PubMed

Seligmann, Hervé

2016-01-01

In mitochondria, secondary structures punctuate post-transcriptional RNA processing. Recently described transcripts match the human mitogenome after systematic deletions of every 4th, respectively every 4th and 5th nucleotides, called delRNAs. Here I explore predicted stem-loop hairpin formation by delRNAs, and their associations with delRNA transcription and detected peptides matching their translation. Despite missing 25, respectively 40% of the nucleotides in the original sequence, del-transformed sequences form significantly more secondary structures than corresponding randomly shuffled sequences, indicating biological function, independently of, and in combination with, previously detected delRNA and thereof translated peptides. Self-hybridization decreases delRNA abundances, indicating downregulation. Systematic deletions of the human mitogenome reveal new, unsuspected coding and structural informations. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

78 FR 43852 - Correction for the Cairo, IL and Belmond, IA Areas

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-22

... Designation'' ``D.R. Schaal'' paragraph is hereby corrected to include: The following grain elevators are not....: Agvantage F.S., Chapin, Franklin County and Five Star Coop, Rockwell, Cerro Gordo County, Iowa; Sioux City... County; Gold-Eagle, Goldfield, Wright County; and North Central Coop, Holmes, Wright County, Iowa...

Comprehensive Planning Resource Document, 1990-91, for the Kern Community College District.

ERIC Educational Resources Information Center

Cook, Lauraine

This compilation of resources for district planning in 1990-91 provides an overview of demographic, personnel, financial, facilities, and curriculum issues for the Kern Community College District (California) and its member institutions, Bakersfield, Cerro Coso, and Porterville colleges. The 10 sections of the document cover: (1) General…

VizieR Online Data Catalog: UBVI photometry of NGC4337 (Carraro+, 2014)

NASA Astrophysics Data System (ADS)

Carraro, G.; Giorgi, E. E.; Costa, E.; Vazquez, R. A.

2015-11-01

We took UBVI images of NGC 4337 in a 20x20 squared arcmin area during two observing runs, on 2010 Feb 14 and 2010 Mar 11, at Cerro Tololo Inter-American Observatory, using the 0.9m and the 1.0m telescopes. (1 data file).

Null geodesics and wave front singularities in the Gödel space-time

NASA Astrophysics Data System (ADS)

Kling, Thomas P.; Roebuck, Kevin; Grotzke, Eric

2018-01-01

We explore wave fronts of null geodesics in the Gödel metric emitted from point sources both at, and away from, the origin. For constant time wave fronts emitted by sources away from the origin, we find cusp ridges as well as blue sky metamorphoses where spatially disconnected portions of the wave front appear, connect to the main wave front, and then later break free and vanish. These blue sky metamorphoses in the constant time wave fronts highlight the non-causal features of the Gödel metric. We introduce a concept of physical distance along the null geodesics, and show that for wave fronts of constant physical distance, the reorganization of the points making up the wave front leads to the removal of cusp ridges.

Functional characterization of a basic helix-loop-helix (bHLH) transcription factor GhDEL65 from cotton (Gossypium hirsutum).

PubMed

Shangguan, Xiao-Xia; Yang, Chang-Qing; Zhang, Xiu-Fang; Wang, Ling-Jian

2016-10-01

Cotton fiber is proposed to share some similarity with the Arabidopsis thaliana leaf trichome, which is regulated by the MYB-bHLH-WD40 transcription complex. Although several MYB transcription factors and WD40 family proteins in cotton have been characterized, little is known about the role of bHLH family proteins in cotton. Here, we report that GhDEL65, a bHLH protein from cotton (Gossypium hirsutum), is a functional homologue of Arabidopsis GLABRA3 (GL3) and ENHANCER OF GLABRA3 (EGL3) in regulating trichome development. Transcripts of GhDEL65 were detected in 0 ∼ 1 days post-anthesis (DPA) ovules and abundant in 3-DPA fibers, implying that GhDEL65 may act in early fiber development. Ectopic expression of GhDEL65 in Arabidopsis gl3 egl3 double mutant partly rescued the trichome development, and constitutive expression of GhDEL65 in wild-type plants led to increased trichome density on rosette leaves and stems, mainly by activating the transcription of two key positive regulators of trichome development, GLABRA1 (GL1) and GLABRA2 (GL2), and suppressed the expression of a R3 single-repeat MYB factor TRIPTYCHON (TRY). GhDEL65 could interact with cotton R2R3 MYB transcription factors GhMYB2 and GhMYB3, as well as the WD40 protein GhTTG3, suggesting that the MYB-bHLH-WD40 protein complex also exists in cotton fiber cell, though its function in cotton fiber development awaits further investigation. © 2016 Scandinavian Plant Physiology Society.

CONTAMINACIÓN AMBIENTAL, VARIABILIDAD CLIMÁTICA Y CAMBIO CLIMÁTICO: UNA REVISIÓN DEL IMPACTO EN LA SALUD DE LA POBLACIÓN PERUANA

PubMed Central

Gonzales, Gustavo F.; Zevallos, Alisson; Gonzales-Castañeda, Cynthia; Nuñez, Denisse; Gastañaga, Carmen; Cabezas, César; Naeher, Luke; Levy, Karen; Steenland, Kyle

2015-01-01

RESUMEN El presente artículo es una revisión sobre la contaminación del agua, el aire y el efecto del cambio climático en la salud de la población peruana. Uno de los principales contaminantes del aire es el material particulado menor de 2,5 μ (PM 2,5), en la ciudad de Lima, anualmente 2300 muertes prematuras son atribuibles a este contaminante. Otro problema es la contaminación del aire domiciliario por el uso de cocinas con combustible de biomasa, donde la exposición excesiva a PM 2,5 dentro de las casas es responsable de aproximadamente 3000 muertes prematuras anuales entre adultos, con otro número desconocido de muertes entre niños debido a infecciones respiratorias. La contaminación del agua tiene como principales causas los desagües vertidos directamente a los ríos, minerales (arsénico) de varias fuentes, y fallas de las plantas de tratamiento. En el Perú, el cambio climático puede impactar en la frecuencia y severidad del fenómeno de El Niño oscilación del sur (ENSO) que se ha asociado con un incremento en los casos de enfermedades como cólera, malaria y dengue. El cambio climático incrementa la temperatura y puede extender las áreas afectadas por enfermedades transmitidas por vectores, además de tener efecto en la disponibilidad del agua y en la contaminación del aire. En conclusión, el Perú, pasa por una transición de factores de riesgo ambientales, donde coexisten riesgos tradicionales y modernos, y persisten los problemas infecciosos y crónicos, algunos de los cuales se asocian con problemas de contaminación de agua y de aire. PMID:25418656

Impacto del Seguro Popular en el gasto catastrófico y de bolsillo en el México rural y urbano, 2005–2008

PubMed Central

Sosa-Rubí, Sandra G; Salinas-Rodríguez, Aarón; Galárraga, Omar

2016-01-01

Objetivo Estimar el efecto del Seguro Popular (SP) sobre la incidencia del gasto catastrófico en salud (GCS) y sobre el gasto de bolsillo en salud (GBS) en el mediano plazo. Material y métodos Con base en la Encuesta de Evaluación del Seguro Popular (2005–2008), se analizaron los resultados del efecto del SP en la cohorte rural para dos años de seguimiento (2006 y 2008) y en la cohorte urbana para un año (2008). Resultados A nivel conglomerado no se detectaron efectos del SP. A nivel hogar se encontró que el SP tiene un efecto protector en el GCS y en el GBS en consulta externa y hospitalización en zonas rurales; y efectos significativos en la reducción de GBS en consulta externa en zonas urbanas. Conclusiones El SP se muestra como un programa efectivo para proteger a los hogares contra gastos de bolsillo por motivos de salud en el mediano plazo. PMID:22282205

Atmospheric scintillation at Dome C, Antarctica: implications for photometry and astrometry

NASA Astrophysics Data System (ADS)

Kenyon, S.; Lawrence, J.; Ashley, M. C. B.; Storey, J. W. V.; Tokovinin, A.; Fossat, E.

2006-08-01

Night-time turbulence profiles of the atmosphere above Dome C, Antarctica, were measured during 2004, using a MASS instrument. We compare this data with turbulence profiles above Cerro Tololo and Cerro Pachon, also measured with a MASS, and find, with the exception of the owest layer, that Dome C has significantly less turbulence. In addition, the integrated at turbulence 16 km above Dome C is always less than the median values at the two Chilean sites. Using average wind speed profiles, we assess the photometric noise produced by scintillation, and the atmospheric contribution to the error budget in narrow angle differential astrometry. In comparison with the two mid-latitude sites in Chile, Dome C offers a potential gain of about 3.6 in both photometric precision (for long integrations) and narrow-angle astrometry precision. Although the data from Dome C cover a fairly limited time frame, they lend strong support to expectations that Dome C will offer significant advantages for photometric and astrometric studies.

A new Miocene baleen whale from Peru deciphers the dawn of cetotheriids

PubMed Central

2017-01-01

Cetotheriidae are an iconic, nearly extinct family of baleen whales (Mysticeti) with a highly distinct cranial morphology. Their origins remain a mystery, with even the most archaic species showing a variety of characteristic features. Here, we describe a new species of archaic cetotheriid, Tiucetus rosae, from the Miocene of Peru. The new material represents the first mysticete from the poorly explored lowest portion of the highly fossiliferous Pisco Formation (allomember P0), and appears to form part of a more archaic assemblage than observed at the well-known localities of Cerro Colorado, Cerro los Quesos, Sud-Sacaco and Aguada de Lomas. Tiucetus resembles basal plicogulans (crown Mysticeti excluding right whales), such as Diorocetus and Parietobalaena, but shares with cetotheriids a distinct morphology of the auditory region, including the presence of an enlarged paroccipital concavity. The distinctive morphology of Tiucetus firmly places Cetotheriidae in the context of the poorly understood ‘cetotheres’ sensu lato, and helps to resolve basal relationships within crown Mysticeti. PMID:28989761

Phoenix Rising: The Helen Sawyer Hogg Telescope Finds a New Home in Argentina.

NASA Astrophysics Data System (ADS)

Garrison, R. F.; Levato, O. H.

2004-12-01

For 26 years (1971-1997), the University of Toronto operated a very productive 60-cm optical telescope on Carnegie's Cerro Las Campanas in north-central Chile. Due to a series of cutbacks in subsidies through NSERC, Canada's research-funding agency, the doors were closed on 01 July 1997 (Canada Day). Following an agreement between astronomers at DDO (Canada) and CASLEO, Argentina, the telescope and dome were relocated on Cerro Burek in Parque Nacional El Leoncita, Argentina, just on the other side of the Andes from Ovalle, Chile. The new building is 3 meters higher and has a dozen ventilating windows. The result is unexpectedly superior seeing. The average point spread function is 0.7 arcseconds. During construction of the building and rebuilding of the telescope, all decisions were made with the intention of operating the telescope remotely, initially from the warmroom of the CASLEO 2.15 meter telescope and ultimately from Toronto and San Juan.

High-Resolution Data for a Low-Resolution World

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brady, Brendan Williams

2016-05-10

In the past 15 years, the upper section of Cañon de Valle has been severely altered by wildfires and subsequent runoff events. Loss of root structures on high-angle slopes results in debris flow and sediment accumulation in the narrow canyon bottom. The original intent of the study described here was to better understand the changes occurring in watershed soil elevations over the course of several post-fire years. An elevation dataset from 5 years post-Cerro Grande fire was compared to high-resolution LiDAR data from 14 years post-Cerro Grande fire (also 3 years post-Las Conchas fire). The following analysis was motivated bymore » a problematic comparison of these datasets of unlike resolution, and therefore focuses on what the data reveals of itself. The objective of this study is to highlight the effects vegetation can have on remote sensing data that intends to read ground surface elevation.« less

A new Miocene baleen whale from Peru deciphers the dawn of cetotheriids

NASA Astrophysics Data System (ADS)

Marx, Felix G.; Lambert, Olivier; de Muizon, Christian

2017-09-01

Cetotheriidae are an iconic, nearly extinct family of baleen whales (Mysticeti) with a highly distinct cranial morphology. Their origins remain a mystery, with even the most archaic species showing a variety of characteristic features. Here, we describe a new species of archaic cetotheriid, Tiucetus rosae, from the Miocene of Peru. The new material represents the first mysticete from the poorly explored lowest portion of the highly fossiliferous Pisco Formation (allomember P0), and appears to form part of a more archaic assemblage than observed at the well-known localities of Cerro Colorado, Cerro los Quesos, Sud-Sacaco and Aguada de Lomas. Tiucetus resembles basal plicogulans (crown Mysticeti excluding right whales), such as Diorocetus and Parietobalaena, but shares with cetotheriids a distinct morphology of the auditory region, including the presence of an enlarged paroccipital concavity. The distinctive morphology of Tiucetus firmly places Cetotheriidae in the context of the poorly understood `cetotheres' sensu lato, and helps to resolve basal relationships within crown Mysticeti.

Wave maps from Gödel's universe

NASA Astrophysics Data System (ADS)

Barletta, Elisabetta; Dragomir, Sorin; Magliaro, Marco

2014-10-01

Using a result by Koch (1988 Trans. Am. Math. Soc. 307 827-41) we realize Gödel's universe G_{α }^{4}=({{{R}}^{4}},{{g}_{α}}) as the total space of a principal {R}-bundle over a strictly pseudo-convex CR manifold M3 and exploit the analogy between {{g}_{Yalpha;}} and Fefferman's metric {{F}_{θ}} (Fefferman 1976 Ann. Math. 103 395-416 104 393-4) to show that for any {R}-invariant wave map Φ of G_{α}^{4} into a Riemannian manifold N, the corresponding base map φ :{{M}^{3}}\\to N is subelliptic harmonic, with respect to a canonical choice of contact form θ on M3. We show that the subelliptic Jacobi operator J_{b}^{φ} of ϕ has a discrete Dirichlet spectrum on any bounded domain D\\subset {{M}^{3}} supporting the Poincaré inequality on \\mathop{W}\\limits^{\\circ }{}_{H}^{1,2}(D,{{φ}^{-1}}TN) and Kondrakov compactness, i.e. compactness of the embedding \\mathop{W}\\limits^{\\circ }{}_{H}^{1,2}(D,{{φ }^{-1}}TN)\\hookrightarrow {{L}^{2}}(D,{{φ}^{-1}}TN). We exhibit an explicit solution π :G_{α}^{4}\\to {{M}^{3}} to the wave map system on G_{α}^{4}, of index in{{d}^{Ω}}(π)\\geqslant 1 for any bounded domain Ω \\subset G_{α}^{4}. Mounoud's distance (Mounoud 2001 Differ. Geom. Appl. 15 47-57) d_{{{G}_{0}}, Ω }^{∞}({{g}_{α }}, {{F}_{θ}}) is bounded below by a constant depending only on the rotation frequency of Gödel's universe, thus giving a measure of the bias of {{g}_{α}} from being Fefferman like in the region Ω \\subset {{{R}}^{4}}.

Biotic association and palaeoenvironmental reconstruction of the "Loma del Pterodaustro" fossil site (Early Cretaceous, Argentina)

USGS Publications Warehouse

Chiappe, L.; Rivarola, D.; Cione, A.; Fregenal-Martinez, M.; Sozzi, H.; Buatois, L.; Gallego, O.; Laza, J.; Romero, E.; Lopez-Arbarello, A.; Buscalioni, A.; Marsicano, C.; Adamonis, S.; Ortega, F.; McGehee, S.; Di, Iorio O.

1998-01-01

A sedimentological analysis of the basal section of the Early Cretaceous, lacustrine Lagarcito Formation at "Loma del Pterodaustro" (San Luis, Argentina) and a summary of its biological components are presented. Three sedimentological facies can be recognized in the basal sequence of the Lagarcito Formation. Fossil remains are particularly abundant in laminated claystones of a facies interpreted as deposits formed in offshore areas of the lake. The preservation of delicate structures allows recognition of these deposits as a Konservat Lagersta??tte. Up to now, rocks at "Loma del Pterodaustro" have yielded plants, conchostracans, semionotid and pleuropholid fishes, pterodactyloid pterosaurs, and a variety of invertebrate traces. The chronology of the Lagarcito Formation is discussed and it is concluded that this unit is of Albian age. The palaeoenvironment of deposition of the basal sequence of the Lagarcito Formation at "Loma del Pterodaustro" is interpreted as a perennial, shallow lake developed within an alluvial plain, under semiarid climatic conditions.

Integrated global background monitoring network. Preliminary results from Torres del Paine and Olympic National Parks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiersma, G.B.; Kohler, A.; Boelcke, C.

1985-10-01

During 1984, a pilot project was initiated for monitoring pollution at Torres del Paine National Park in southern Chile and Olympic National Park in the United States. These are two of three initial sites that are to be established as part of an integrated global backgound monitoring network. Eventually, the plan is to establish a world-wide system of such sites. We collected and analyzed samples of the soil, water, air, and two species of plants (moss and lichen). We also collected and analyzed samples of the forest litter. We compared the samples of soil and vegetation against reference samples. Wemore » also compared samples of soil, vegetation, and of organic material from Torres del Paine against similar samples from Olympic and Sequoia-Kings Canyon National Parks in the United States. Although the data is preliminary, it is in agreement with out initial hypothesis that Torres del Paine and Olympic National Parks are not a polluted sites.« less

The Global Oscillation Network Group site survey, 2: Results

NASA Technical Reports Server (NTRS)

Hill, Frank; Fischer, George; Forgach, Suzanne; Grier, Jennifer; Leibacher, John W.; Jones, Harrison P.; Jones, Patricia B.; Kupke, Renate; Stebbins, Robin T.; Clay, Donald W.

1994-01-01

The Global Oscillation Network Group (GONG) Project will place a network of instruments around the world to observe solar oscillations as continuously as possible for three years. The Project has now chosen the six network sites based on analysis of survey data from fifteen sites around the world. The chosen sites are: Big Bear Solar Observatory, California; Mauna Loa Solar Observatory, Hawaii; Learmonth Solar Observatory, Australia; Udaipur Solar Observatory, India; Observatorio del Teide, Tenerife; and Cerro Tololo Interamerican Observatory, Chile. Total solar intensity at each site yields information on local cloud cover, extinction coefficient, and transparency fluctuations. In addition, the performance of 192 reasonable networks assembled from the individual site records is compared using a statistical principal components analysis. An accompanying paper descibes the analysis methods in detail; here we present the results of both the network and individual site analyses. The selected network has a duty cycle of 93.3%, in good agreement with numerical simulations. The power spectrum of the network observing window shows a first diurnal sidelobe height of 3 x 10(exp -4) with respect to the central component, an improvement of a factor of 1300 over a single site. The background level of the network spectrum is lower by a factor of 50 compared to a single-site spectrum.

High pressure breakdown of antigorite to spinifex-textured olivine and orthopyroxene, SE Spain

NASA Astrophysics Data System (ADS)

Trommsdorff, V.; Sánchez-Vizcaíno, V. López; Gómez-Pugnaire, M. T.; Müntener, O.

The prograde, high pressure, transition from antigorite serpentinite to enstatite-olivine rock occurs along a tectonically undisturbed profile at Cerro del Almirez, SE Spain. The reactant assemblage is antigorite + olivine with tremolite rimming precursor diopside. The product assemblage of tremolite + chlorite + enstatite + olivine has a spinifex-like texture with arborescent or radiating olivine elongated parallel to [001] and with radially grown enstatite. Product enstatite is very poor in Al2O3. Due to numerous oriented submicroscopic inclusions of chromian magnetite, product olivine has a brownish pleochroism and a bulk chromium content similar to precursor antigorite. Titanian clinohumite with a fluorine content of 0.45-0.50 wt% persisted beyond the breakdown of antigorite. The partitioning of iron and magnesium amongst the silicate phases is almost identical to that at lower pressures. Average Kd values Mn/Mg and Ni/Mg are 0.17 and 0.70 for antigorite-olivine pairs and 1.83 and 0.22 for orthopyroxene-olivine pairs, respectively. These data are useful in discriminating generations of olivine grown on each other. From the field data a phase diagram topology for a portion of the system CaO-MgO-SiO2-H2O is derived. This topology forms the basis for extrapolations into inaccessible P-T regions.

Acorenone B: AChE and BChE Inhibitor as a Major Compound of the Essential Oil Distilled from the Ecuadorian Species Niphogeton dissecta (Benth.) J.F. Macbr.

PubMed

Calva, James; Bec, Nicole; Gilardoni, Gianluca; Larroque, Christian; Cartuche, Luis; Bicchi, Carlo; Montesinos, José Vinicio

2017-10-31

This study investigated the chemical composition, physical proprieties, biological activity, and enantiomeric analysis of the essential oil from the aerial parts of Niphogeton dissecta (culantrillo del cerro) from Ecuador, obtained by steam distillation. The qualitative and quantitative analysis of the essential oil was realized by gas chromatographic and spectroscopic techniques (GC-MS and GC-FID). Acorenone B was identified by GC-MS and NMR experiments. The enantiomeric distribution of some constituents has been assessed by enantio-GC through the use of a chiral cyclodextrin-based capillary column. We identified 41 components that accounted for 96.46% of the total analyzed, the major components were acorenone B (41.01%) and (E)-β-ocimene (29.64%). The enantiomeric ratio of (+)/(-)-β-pinene was 86.9:13.1, while the one of (+)/(-)-sabinene was 80.9:19.1. The essential oil showed a weak inhibitory activity, expressed as Minimal Inhibitory Concentration (MIC), against Enterococcus faecalis (MIC 10 mg/mL) and Staphylococcus aureus (MIC 5 mg/mL). Furthermore, it inhibited butyrylcholinesterase with an IC 50 value of 11.5 μg/mL. Pure acorenone B showed inhibitory activity against both acetylcholinesterase and butyrylcholinesterase, with IC 50 values of 40.8 μg/mL and 10.9 μg/mL, respectively.

Acorenone B: AChE and BChE Inhibitor as a Major Compound of the Essential Oil Distilled from the Ecuadorian Species Niphogeton dissecta (Benth.) J.F. Macbr

PubMed Central

Calva, James; Bec, Nicole; Gilardoni, Gianluca; Larroque, Christian; Cartuche, Luis; Bicchi, Carlo; Montesinos, José Vinicio

2017-01-01

This study investigated the chemical composition, physical proprieties, biological activity, and enantiomeric analysis of the essential oil from the aerial parts of Niphogeton dissecta (culantrillo del cerro) from Ecuador, obtained by steam distillation. The qualitative and quantitative analysis of the essential oil was realized by gas chromatographic and spectroscopic techniques (GC-MS and GC-FID). Acorenone B was identified by GC-MS and NMR experiments. The enantiomeric distribution of some constituents has been assessed by enantio-GC through the use of a chiral cyclodextrin-based capillary column. We identified 41 components that accounted for 96.46% of the total analyzed, the major components were acorenone B (41.01%) and (E)-β-ocimene (29.64%). The enantiomeric ratio of (+)/(−)-β-pinene was 86.9:13.1, while the one of (+)/(−)-sabinene was 80.9:19.1. The essential oil showed a weak inhibitory activity, expressed as Minimal Inhibitory Concentration (MIC), against Enterococcus faecalis (MIC 10 mg/mL) and Staphylococcus aureus (MIC 5 mg/mL). Furthermore, it inhibited butyrylcholinesterase with an IC50 value of 11.5 μg/mL. Pure acorenone B showed inhibitory activity against both acetylcholinesterase and butyrylcholinesterase, with IC50 values of 40.8 μg/mL and 10.9 μg/mL, respectively. PMID:29088082

Fish faunas from the Late Jurassic (Tithonian) Vaca Muerta Formation of Argentina: One of the most important Jurassic marine ichthyofaunas of Gondwana

NASA Astrophysics Data System (ADS)

Gouiric-Cavalli, Soledad; Cione, Alberto Luis

2015-11-01

The marine deposits of the Vaca Muerta Formation (Tithonian-Berriasian) houses one of the most diverse Late Jurassic ichthyofaunas of Gondwana. However, most of the specimens remain undescribed. Jurassic fishes have been recovered from several localities at Neuquén Province (i.e., Picún Leufú, Plaza Huincul, Cerro Lotena, Portada Las Lajas, Los Catutos, and Arroyo Covunco) but also from Mendoza Province (i.e., La Valenciana, Los Molles, and Arroyo del Cajón Grande). Presently, the fish fauna of Los Catutos, near Zapala city (Neuquén Province), has yielded the highest number of specimens, which are taxonomically and morphologically diverse. At Los Catutos locality, the Vaca Muerta Formation is represented by the Los Catutos Member, which is considered the only lithographic limestones known in the Southern Hemisphere. Here, we review the Tithonian fish faunas from the Vaca Muerta Formation. During Late Jurassic times, the actual Argentinian territory could have been a morphological diversification center, at least for some actinopterygian groups. The apparently lower species diversity recorded in marine Jurassic ichthyofaunas of Argentina (and some Gondwanan countries) in comparison with Chilean and European fish faunas could be related to the fish paleontological research history in Gondwana and the low number of detailed studies of most of specimens recorded.

New evidence of surge-type glaciers in the Central Andes of Argentina and Chile

NASA Astrophysics Data System (ADS)

Bolch, T.; Falaschi, D.; Lenzano, M. G.; Tadono, T.; Lenzano, L. E.

2017-12-01

In contrast to the large surge-type glacier clusters widely known for several mountain ranges around the world, the presence of surging glaciers in the Andes has been historically seen as marginal. Based on the analysis of satellite imagery and DEM differencing, coupled with aerial archival data, we identified 21 surge-type glaciers in the Central Andes, out of which four of them are confirmed surge-type, six are very-probable surge-type, and eleven are possible surge-type. The geodetic mass balance estimation of 12 glaciers for the 2000-2011 period, which encompasses the latest surge events, mostly showed either moderately negative or positive patterns (-0.5 to 0.3 m w.e. a-1). Additionally, we calculated maximum surface velocities of 6.3 ±1.9 m d-1 and 3.5 ±1.2 m d-1 for the Piuquenes and Noreste del Cerro Alto glaciers during the latest two identifiable surge events (1985-1987 and 2003-2007), and preliminarily determined surge cycles of 10 and 20 years for these two glaciers, respectively. The synchronicity of recent and past glacier surges and the coincidence with anomalously cold, snowy periods point out to a common climatic control over glacier surges in this region.

Development and validation of an automated delirium risk assessment system (Auto-DelRAS) implemented in the electronic health record system.

PubMed

Moon, Kyoung-Ja; Jin, Yinji; Jin, Taixian; Lee, Sun-Mi

2018-01-01

A key component of the delirium management is prevention and early detection. To develop an automated delirium risk assessment system (Auto-DelRAS) that automatically alerts health care providers of an intensive care unit (ICU) patient's delirium risk based only on data collected in an electronic health record (EHR) system, and to evaluate the clinical validity of this system. Cohort and system development designs were used. Medical and surgical ICUs in two university hospitals in Seoul, Korea. A total of 3284 patients for the development of Auto-DelRAS, 325 for external validation, 694 for validation after clinical applications. The 4211 data items were extracted from the EHR system and delirium was measured using CAM-ICU (Confusion Assessment Method for Intensive Care Unit). The potential predictors were selected and a logistic regression model was established to create a delirium risk scoring algorithm to construct the Auto-DelRAS. The Auto-DelRAS was evaluated at three months and one year after its application to clinical practice to establish the predictive validity of the system. Eleven predictors were finally included in the logistic regression model. The results of the Auto-DelRAS risk assessment were shown as high/moderate/low risk on a Kardex screen. The predictive validity, analyzed after the clinical application of Auto-DelRAS after one year, showed a sensitivity of 0.88, specificity of 0.72, positive predictive value of 0.53, negative predictive value of 0.94, and a Youden index of 0.59. A relatively high level of predictive validity was maintained with the Auto-DelRAS system, even one year after it was applied to clinical practice. Copyright © 2017. Published by Elsevier Ltd.

La utilizacion de los mapas conceptuales en la ensenanza de biologia y su efecto sobre el dominio del proceso de fotosintesis en los estudiantes universitarios

NASA Astrophysics Data System (ADS)

Gonzalez Rivera, Maria M.

Se investigo el efecto de los mapas conceptuales sobre el dominio del proceso de fotosintesis en estudiantes universitarios. La investigacion utilizo dos estrategias: mapas conceptuales individuales y mapas conceptuales colaborativos, con el fin de investigar si existen diferencias significativas en el dominio del proceso de fotosintesis. El analisis de los datos incluyo aspectos cualitativos y cuantitativos. Se desprende del estudio que el 80% de los estudiantes describen la utilizacion de los mapas conceptuales como una experiencia beneficiosa. El 70% de los estudiantes expreso que los mapas conceptuales son utiles en el aprendizaje del proceso de fotosintesis y el 61% indico que facilitan la comprension de los conceptos. Los hallazgos mas importantes del analisis cuantitativo indican que los estudiantes que utilizaron los mapas conceptuales mejoraron significativamente su desempeno en la posprueba global. Se utilizo la prueba Mann-Whitney para investigar si existian diferencias significativas en la posprueba y preprueba global, el valor de W = 1945.0, para un valor p de 0.00, lo cual establece diferencias significativas. Para determinar si existian diferencias significativas entre la posprueba y preprueba del grupo individual, se realizo la prueba nuevamente. El valor de W correspondio a 490.5, que es significativo, con un valor p de 0.00. Se concluye que existen diferencias significativas entre la ejecucion de la posprueba y preprueba del grupo individual. Los datos proveen suficiente evidencia para sostener que los estudiantes que utilizaron la estrategia de mapas conceptuales individuales mejoraron el dominio del proceso de fotosintesis significativamente. Se realizo nuevamente la prueba para los resultados de posprueba y preprueba del grupo colaborativo. El valor de W correspondio a 446 con un valor p de 0.00. Se concluyo que existen diferencias significativas entre la ejecucion de la posprueba y preprueba del grupo colaborativo. Finalmente, se efectuo una

Violación del Principio de Equivalencia en Teorías con Dilatón de Cuerdas

NASA Astrophysics Data System (ADS)

Landau, S. J.; Sisterna, P. D.; Vucetich, H.

Se estudian las violaciones al Principio de Equivalencia en Teorías con Dilatón de Cuerdas. En estos modelos, algunas de las constantes fundamentales dependen del espacio y del tiempo. Se muestra que los experimentos de caída libre no tienen aún precisión como para poner límites a los parámetros de la teoría.

22. Photographic copy of 1889 linen drawing of reservoir. Approximately ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. Photographic copy of 1889 linen drawing of reservoir. Approximately two and a half feet by four feet. Delineator unknown, original currently located in the Sangre de Cristo Water Company files. - Two Mile Reservoir, Santa Fe River, intersection of Canyon & Cerro Gordo Roads, Santa Fe, Santa Fe County, NM

23. Photographic copy of 1883 ink and water color drawing ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. Photographic copy of 1883 ink and water color drawing of the Old Stone Dam. Original located in the office of the director of the Sangre de Cristo Water Company. - Two Mile Reservoir, Santa Fe River, intersection of Canyon & Cerro Gordo Roads, Santa Fe, Santa Fe County, NM

Residential metal contamination and potential health risks of exposure in adobe brick houses in Potosí, Bolivia

EPA Science Inventory

Potosí, Bolivia, is the site of centuries of historic and present-day mining of the Cerro Rico Mountain, known for its rich polymetallic deposits, and was the site of large-scale Colonial era silver refining operations, both of which have left a legacy of pollution. In this study...

The Second Tennessee Cavalry in the American Civil War

DTIC Science & Technology

2014-06-13

Wheeler split his command and allowed Brigadier General John “Cerro Gordo” Williams to take two brigades and attack a Federal garrison at Strawberry ...to Strawberry Plains. However, evidence from Edwin Drake’s work, and Andrew Williams’s diary, indicates that at least some portion of the regiment

History and use of del Nido cardioplegia solution at Boston Children's Hospital.

PubMed

Matte, Gregory S; del Nido, Pedro J

2012-09-01

Cardioplegia is an integral and essential method of myocardial protection for patients of all ages requiring cardiac surgery in which the heart must be stopped. Numerous cardioplegia solutions and delivery methods have been developed. The del Nido cardioplegia solution has been in use for 18 years at Boston Children's Hospital. This is a unique four parts crystalloid to one part whole blood formulation that is generally used in a single-dose fashion. Although the formulation was originally developed for use in pediatric and infant patients, its use for adult cardiac surgery has been expanding. National and international inquiries to our institution regarding this cardioplegia have been increasing over the last 2 years. We present the developmental history, supporting theory, and current protocol for use of what is now referred to as del Nido cardioplegia.

F508del-CFTR rescue: a matter of cell stress response.

PubMed

Nieddu, Erika; Pollarolo, Benedetta; Merello, Luisa; Schenone, Silvia; Mazzei, Mauro

2013-01-01

Cystic fibrosis (CF) is a common inherited fatal disease affecting 70,000 people worldwide, with a median predicted age of survival of approximately 38 years. The deletion of Phenylalanine in position 508 of the Cystic Fibrosis Transmembrane conductance Regulator (F508del-CFTR) is the most common mutation in CF patients: the deleted protein, not properly folded, is degraded. To date no commercial drugs are available. Low temperature, some osmolytes and conditions able to induce heat shock protein 70 (Hsp70) expression and heat shock cognate 70 (Hsc70) inhibition result in F508del-CFTR rescue, hence restoring its physiological function: this review sheds light on the correlation between these several evidences. Interestingly, all these approaches have a role in the cell stress response (CSR), a set of cell reactions to stress. In addition, unpredictably, F508del-CFTR rescue has to be considered in the frame of CSR: entities that induce - or are induced during - the CSR are, in general, also able to correct trafficking defect of CFTR. Specifically, the low temperature induces, by definition, a CSR; osmolytes, such as glycerol and trimethylamine N-oxide (TMAO), are products of the CSR; pharmacological correctors, such as Matrine and 4-phenylbutirric acid (4PBA), down-regulate the constitutive Hsc70 in favor of an up-regulation of the inducible chaperone Hsp70, another component of the CSR. The identification of a common mechanism of action for different types of correctors could drive the discovery of new active molecules in CF, overcoming methods clinically inapplicable, such as the low temperature.

A review on Balanites aegyptiaca Del (desert date): phytochemical constituents, traditional uses, and pharmacological activity

PubMed Central

Chothani, Daya L.; Vaghasiya, H. U.

2011-01-01

Balanites aegyptiaca Del. (Zygophyllaceae), known as ‘desert date,’ is spiny shrub or tree up to l0 m tall, widely distributed in dry land areas of Africa and South Asia. It is traditionally used in treatment of various ailments i.e. jaundice, intestinal worm infection, wounds, malaria, syphilis, epilepsy, dysentery, constipation, diarrhea, hemorrhoid, stomach aches, asthma, and fever. It contains protein, lipid, carbohydrate, alkaloid, saponin, flavonoid, and organic acid. Present review summarizes the traditional claims, phytochemistry, and pharmacology of B. aegyptiaca Del reported in scientific literature. PMID:22096319

Moléculas orgánicas obtenidas en simulaciones experimentales del medio interestelar.

NASA Astrophysics Data System (ADS)

Muñoz-Caro, Guillermo Manuel

Las nubes moleculares son regiones de formación de estrellas, con temperaturas cinéticas entre 10-50 K y densidades de 103-106 átomos cm-3. Su materia está formada por gas y polvo interestelar. Estas partículas de polvo están cubiertas por una fina capa de hielo, de unos 0.01 μm, que contiene H2O y a menudo CO, CO2, CH3OH y NH3. El hielo es presumiblemente irradiado por fotones ultravioleta y rayos cósmicos en las zonas poco profundas de las nubes moleculares y las regiones circunestelares. En un sistema de vacío, P ˜ 10-7 mbar, simulamos la deposición de hielo a partir de 10 K y la irradiación ultravioleta por medio de una lámpara de descarga de hidrógeno activada con microondas. La evolución del hielo se observa por medio de un espectrómetro infrarrojo. De este modo es posible determinar la composición del hielo observado en el medio interestelar y predecir la presencia de moléculas aún no detectadas en el espacio, que han sido producto del procesamiento del hielo en nuestros experimentos. También es posible calentar el sistema hasta temperatura ambiente para sublimar el hielo depositado. Cuando el hielo ha sido previamente irradiado, se observa un residuo compuesto por moléculas orgánicas complejas, algunas prebióticas, como varios ácidos carboxílicos, aminas, amidas, ésteres y en menor proporción moléculas heterocíclicas y aminoácidos. Algunas de estas moléculas podrían detectarse en estado gaseoso por medio de observaciones milimétricas y de radio. También podrían estar presentes en el polvo cometario, cuyo análisis químico está planeado por las misiones Stardust y Rosetta. Mientras tanto, nuestro grupo está llevando a cabo el análisis de partículas de polvo interplanetario (IDPs), algunas de las cuales pueden ser de origen cometario. Al igual que ocurre con los productos obtenidos por irradiación del hielo en nuestros experimentos, algunas IDPs son ricas en material orgánico que contiene oxígeno.

Meningiomas del foramen magno: Reporte de 12 casos y revisión de la literatura

PubMed Central

Campero, Álvaro; Ajler, Pablo; Roman, Guillermo; Rivadeneira, Conrado

2017-01-01

Resumen Objetivo: El propósito del presente trabajo es presentar los resultados de 12 pacientes con diagnóstico de meningiomas del foramen magno (MFM), de localización anterior o lateral, operados con técnicas microquirúrgicas. Método: Desde Junio de 2005 a Diciembre de 2016, 12 pacientes con diagnóstico de MFM fueron intervenidos quirúrgicamente. Se evaluó: edad, sexo, localización de la lesión (anterior o lateral), sintomatología, tipo de abordaje utilizado y resultados postoperatorios. Resultados: De los pacientes intervenidos, 8 fueron mujeres y 4 varones. La edad promedio fue de 47 años. La localización fue anterior en 8 casos y lateral en 4 casos. La sintomatología más frecuente fue dolor occipito-cervical (8 casos), seguido de tetraparesia (3 casos). En los pacientes con MFM de localización anterior se realizó un abordaje extremo-lateral transcondilar (ELTC), mientras que en los tumores laterales el abordaje fue extremo-lateral retrocondilar (ELRC). En 10 casos la resección fue completa. En dos pacientes fue necesario dejar una pequeña lámina de meningioma sobre la arteria vertebral y a nivel del foramen yugular. Como complicaciones postoperatorias, 3 pacientes presentaron una paresia del XII nervio craneano y 2 pacientes paresia del XI nervio craneano; además, 1 paciente presentó una fístula de LCR. Conclusión: La cirugía de los MFM de localización anterior y lateral puede ser realizada de forma segura y efectiva. Es necesario: a) buen conocimiento anatómico de la región; b) disecar los músculos de la nuca en 2 planos, exponiendo el triángulo suboccipital y la arteria vertebral (AV); 3) realizar un abordaje ELRC en los tumores laterales, y ELTC en los tumores anteriores; y 4) buena técnica microquirúrgica. PMID:29142778

3. Historic American Buildings Survey, Frederik C. Gjessing, Photographer April ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey, Frederik C. Gjessing, Photographer April 19, 1954 MASONRY DETAIL SOUTHEAST CORNER OF BATTERY. - Escambron Bateria, Puerta de Tierra, San Juan, San Juan Municipio, PR

Contribución al flujo infrarrojo de las estrellas Be de la recombinación dielectrónica del MgII

NASA Astrophysics Data System (ADS)

Cruzado, A.; di Rocco, H.; Ringuelet, A.

Para evaluar la contribución del proceso de recombinación dielectrónica del átomo de MgII al exceso de flujo infrarrojo observado en las estrellas Be, calculamos la energía emitida en las líneas originadas por este proceso. Se evaluaron los efectos de las condiciones físicas del medio, como la temperatura electrónica y la densidad electrónica, sobre el flujo emitido. Se consideró también la influencia de una posible opacidad.

Synthetic Spectral Analysis of the Far Ultraviolet Spectra of the Old Nova HR Del

NASA Astrophysics Data System (ADS)

Robertson, Jordan; Sion, E.

2012-05-01

We present a synthetic spectral analysis of the archival IUE far ultraviolet spectra of the post-nova, HR Del (Nova Del 1967). The system has an estimated white dwarf mass of 0.55 Msun (Ritter and Kolb 2003), orbital period P_orb = 0.214165 days, estimated orbital inclination of 40 degrees (Keurster 1988) and distance determinations in the literature ranging from 970 pc to 285 pc. The spectra reveal P Cygni profiles indicative of wind outflow from the disk and closely resemble the IUE spectra of UX UMa nova-likes, which have never had recorded outbursts. We de-reddened the archival IUE spectra using E(B-V) = 0.16. Our synthetic spectral analysis utilized optically thick, steady state accretion disk models and white dwarf model atmospheres that we constructed using TLUSTY and SYNSPEC (Hubeny 1988, Hubeny and Lanz (1995). Our input parameters were the white dwarf mass, inclination and a range of accretion rates for which we found the best-fitting model. We report the results of our model fitting and compare HR Del with other post-novae at comparable times past their nova outburst. This work was supported by NSF grant 0807892 to Villanova University

La meridiana di Egnazio Danti nella Torre dei Venti in Vaticano: un'icona della riforma Gregoriana del calendario

NASA Astrophysics Data System (ADS)

Sigismondi, Costantino

2014-05-01

La Torre dei Venti domina l’angolo Sud Ovest del cortile della Pigna (nell'area dei Musei Vaticani), ed è inclusa negli ambienti dell'Archivio Segreto Vaticano. Non è aperta al pubblico, ma è universalmente nota per la fama che da oltre quattrocento anni la circonda, legata alle vicende della riforma Gregoriana del calendario. La meridiana tracciata da padre Egnazio Danti (1536-1586) nella torre dei Venti, fu visitata anche da Gregorio XIII, probabilmente il 21 marzo 1581 come suppone il padre Stein, per convincersi dell'anticipo ormai arrivato a dieci giorni dell'equinozio di primavera sulla data che il concilio di Nicea aveva fissato al 21 marzo per il computo pasquale. La ricognizione astrometrica del febbraio-marzo 2009 fatta dall'autore viene qui presentata.

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.

PubMed

Chung, W Joon; Goeckeler-Fried, Jennifer L; Havasi, Viktoria; Chiang, Annette; Rowe, Steven M; Plyler, Zackery E; Hong, Jeong S; Mazur, Marina; Piazza, Gary A; Keeton, Adam B; White, E Lucile; Rasmussen, Lynn; Weissman, Allan M; Denny, R Aldrin; Brodsky, Jeffrey L; Sorscher, Eric J

2016-01-01

Small molecules that correct the folding defects and enhance surface localization of the F508del mutation in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) comprise an important therapeutic strategy for cystic fibrosis lung disease. However, compounds that rescue the F508del mutant protein to wild type (WT) levels have not been identified. In this report, we consider obstacles to obtaining robust and therapeutically relevant levels of F508del CFTR. For example, markedly diminished steady state amounts of F508del CFTR compared to WT CFTR are present in recombinant bronchial epithelial cell lines, even when much higher levels of mutant transcript are present. In human primary airway cells, the paucity of Band B F508del is even more pronounced, although F508del and WT mRNA concentrations are comparable. Therefore, to augment levels of "repairable" F508del CFTR and identify small molecules that then correct this pool, we developed compound library screening protocols based on automated protein detection. First, cell-based imaging measurements were used to semi-quantitatively estimate distribution of F508del CFTR by high content analysis of two-dimensional images. We evaluated ~2,000 known bioactive compounds from the NIH Roadmap Molecular Libraries Small Molecule Repository in a pilot screen and identified agents that increase the F508del protein pool. Second, we analyzed ~10,000 compounds representing diverse chemical scaffolds for effects on total CFTR expression using a multi-plate fluorescence protocol and describe compounds that promote F508del maturation. Together, our findings demonstrate proof of principle that agents identified in this fashion can augment the level of endoplasmic reticulum (ER) resident "Band B" F508del CFTR suitable for pharmacologic correction. As further evidence in support of this strategy, PYR-41-a compound that inhibits the E1 ubiquitin activating enzyme-was shown to synergistically enhance F508del rescue by C18, a small

Cayler cardiofacial syndrome and del 22q11: Part of the CATCH22 phenotype

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giannotti, A.; Digilio, M.C.; Marino, B.

1994-11-15

The authors report evidence supporting the hypothesis that del(22)(q11) can be a pathogenetic mechanism for the association between hypoplasia of the depressor anguli oris muscle (DAOM) and conotruncal cardiac malformations. A series of over 180 patients was investigated with deletions of 22q11 with conotruncal defects. About 2/3 of these patients had isolated, nonfamilial cardiac defects. Hemizygosity was searched using the HD7k probe and densitometric analysis. In the patients with molecular evidence of del(22)(q11), hemizygosity was confirmed also using fluorescence in situ hybridization (FISH) with SC11.1 probe. No deletion was found in the parents of hemizygous patients. 16 refs.

[Tierra del Fuego: the scientific-political construction of exclusion and counter-image of the ideal city dweller].

PubMed

Nacach, Gabriela

2012-01-01

Due to its late incorporation into the national State, the social, economic and political setting of the Argentine province Tierra del Fuego differed from that of the rest of the national territory. In the construction of dependent otherness, objectifications and representations were imposed by state-related and non-state-related institutions, among other agencies. In this context, the Salesian mission of La Candelaria and Ushuaia's Jail for recidivists stand out as spaces in which biopolitics was concretised. The native population and criminals in Tierra del Fuego were those to be subjugated. The thesis of the extinction of the Indian and the simultaneous exaltation of the criminal as the subject of progress identified the scientific and political mechanisms by which the exclusion of certain social groups (Tierra del Fuego's indigenous population) and the inclusion of others (criminals) were regulated.

VizieR Online Data Catalog: Faint emission lines in M16, M20, NGC 3603 (Garcia-Rojas+, 2006)

NASA Astrophysics Data System (ADS)

Garcia-Rojas, J.; Esteban, C.; Peimbert, M.; Costado, M. T.; Rodriguez, M.; Peimbert, A.; Ruiz, M. T.

2006-10-01

The observations were made on 2003 March 29, 30 and 31 with UVES, at the VLT Kueyen Telescope in Cerro Paranal Observatory (Chile). We used the standard settings in both the red and blue arms of the spectrograph, covering the spectral region from 3100 to 10400{AA}. (1 data file).

Apollo 9 Mission image - S0-65 Multispectral Photography - Mexico

NASA Image and Video Library

2009-02-19

AS09-26A-3768A (10 March 1969) --- Color infrared photograph of Mexico: Cerro Malinche, east end of neo-volcanic plateau, as seen from the Apollo 9 spacecraft during its 109th revolution of Earth. This picture was taken as a part of the SO65 Multispectral Terrain Photography Experiment.

Confirmation of 5 SN in the Kepler/K2 C16 Field with Gemini

NASA Astrophysics Data System (ADS)

Margheim, S.; Tucker, B. E.; Garnavich, P. M.; Rest, A.; Narayan, G.; Smith, K. W.; Smartt, S.; Kasen, D.; Shaya, E.; Mushotzky, R.; Olling, R.; Villar, A.; Forster, F.; Zenteno, A.; James, D.; Smith, R. Chris

2018-01-01

We report new spectroscopic classifications by KEGS of supernova discovered by Pan-STARRS1 during a targeted search of the Kepler/K2 Campaign 16 field using the Gemini Multi-Object Spectrograph (GMOS) on both the Gemini North Observatory on Mauna Kea, and the Gemini South Observatory on Cerro Pachon.

Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.

PubMed

Chandran, Divya; Rickert, Joshua; Huang, Yingxiang; Steinwand, Michael A; Marr, Sharon K; Wildermuth, Mary C

2014-04-09

In plants, the activation of immunity is often inversely correlated with growth. Mechanisms that control plant growth in the context of pathogen challenge and immunity are unclear. Investigating Arabidopsis infection with the powdery mildew fungus, we find that the Arabidopsis atypical E2F DEL1, a transcriptional repressor known to promote cell proliferation, represses accumulation of the hormone salicylic acid (SA), an established regulator of plant immunity. DEL1-deficient plants are more resistant to pathogens and slightly smaller than wild-type. The resistance and size phenotypes of DEL1-deficient plants are due to the induction of SA and activation of immunity in the absence of pathogen challenge. Moreover, Enhanced Disease Susceptibility 5 (EDS5), a SA transporter required for elevated SA and immunity, is a direct repressed target of DEL1. Together, these findings indicate that DEL1 control of SA levels contributes to regulating the balance between growth and immunity in developing leaves. Copyright © 2014 Elsevier Inc. All rights reserved.

Taos Smart Growth Implementation Assistance: Concepts for the Paseo del Pueblo Sur Corridor

EPA Pesticide Factsheets

This report describes a technical assistance project with Taos, NM, to help make development along State Highway 68, the Paseo del Pueblo Sur commercial corridor, economically stronger and more attractive.

Analysis of density and epitopes of D antigen on the surface of erythrocytes from DEL phenotypic individuals carrying the RHD1227A allele.

PubMed

Gu, Juan; Sun, An-Yuan; Wang, Xue-Dong; Shao, Chao-Peng; Li, Zheng; Huang, Li-Hua; Pan, Zhao-Lin; Wang, Qing-Ping; Sun, Guang-Ming

2014-04-01

The characteristics of the D antigen are important as they influence the immunogenicity of D variant cells. Several studies on antigenic sites have been reported in normal D positive, weak D and partial D cases, including a comprehensive analysis of DEL types in Caucasians. The aim of this study was to assess D antigen density and epitopes on the erythrocyte surface of Asian type DEL phenotypic individuals carrying the RHD1227A allele in the Chinese population. A total of 154 DEL phenotypic individuals carrying the RHD1227A allele were identified through adsorption and elution tests and polymerase chain reaction analysis with sequence-specific primers in the Chinese population. D antigen density on the erythrocyte surface of these individuals was detected using a flow cytometric method. An erythrocyte sample with known D antigen density was used as a standard. Blood samples from D-negative and D-positive individuals were used as controls. In addition, D antigen epitopes on the erythrocyte surface of DEL individuals carrying the RHD1227A allele were investigated with 18 monoclonal anti-D antibodies specific for different D antigen epitopes. The means of the median fluorescence intensity of D antigen on the erythrocyte membrane surface of D-negative, D-positive and DEL individuals were 2.14±0.25, 193.61±11.43 and 2.45±0.82, respectively. The DEL samples were estimated to have approximately 22 D antigens per cell. The samples from all 154 DEL individuals reacted positively with 18 monoclonal anti-D antibodies specific for different D antigen epitopes. In this study, D antigen density on the erythrocyte surface of DEL individuals carrying the RHD1227A allele was extremely low, there being only very few antigenic molecules per cell, but the D antigen epitopes were grossly complete.

Tratamiento Quirúrgico de los Meningiomas del Foramen Óptico, Técnicay Resultados de una Serie de 18 Pacientes

PubMed Central

Goldschmidt, Ezequiel; Ajler, Pablo; Campero, Álvaro; Landriel, Federico; Sposito, Maximiliano; Carrizo, Antonio

2014-01-01

Introducción: los meningiomas del foramen óptico producen un rápido deterioro de la función visual aún cuando su tamaño es pequeño, por eso su diagnóstico y manejo difiere del resto de los meningiomas clinoideos. El propósito de este estudio es presentar la técnica y los resultados de nuestro manejo quirúrgico de meningiomas foraminales (MF). Pacientes y Métodos: se llevó a cabo una revisión de las historias clínicas de 47 pacientes con meningiomas primarios intraorbitarios. Se realizaron 52 cirugías en los pacientes con MF. Se empleó una craneotomía fronto-orbitaria, seguida de una descompresión extradural del canal óptico, resección del componente intraorbitario y exploración intradural del nervio óptico. Resultados: de los 12 pacientes con MF que presentaban la visión conservada, la agudeza visual fue preservada en 7 casos, mejoró en 2, y empeoró en 3. En 18 pacientes, el principal síntoma fue exoftalmos y en 35 pacientes ceguera unilateral. Ocurrieron 6 recurrencias, 2 a 10 años después de la resección quirúrgica. Cinco de ellos fueron reoperados. Se indicó radioterapia después de la recurrencia en 3 pacientes. Conclusión: el manejo de los MF continúa siendo controvertido y frecuentemente se propone un tratamiento conservador. Basados en nuestros hallazgos de frecuente extensión intracraneal, proponemos realizar una resección total o subtotal del tumor, preservando el nervio óptico en pacientes con visión prequirúrgica conservada. PMID:25165616

Heat flow and thermal processes in the Jornada delMuerto, New Mexico

NASA Technical Reports Server (NTRS)

Reiter, M.

1985-01-01

Most heat flow data in rifts are uncertain largely because of hydrologic disturbances in regions of extensive fracturing. Estimates of heat flow in deep petroleum tests within a large basin of the Rio Grande rift, which has suffered little syn-rift fracturing, may begin to provide clearer insight into the relationships between high heat flow and crustal thinning processes. The Jornada del Muerto is a large basin located in the Rio Grande rift of south central New Mexico. The region of interest within the Jornada del Muerto is centered about 30 km east of the town of Truth or Consequences, and is approximately 60 km north-south by 30 km east-west. High heat flows are estimated for the region. Values increase from about 90 mWm(-2) in the northern part of the study area to about 125 mWm(-2) in the southern part. These high heat flows are rather enigmatic because in the immediate vicinities of the sites there is little evidence of Cenozoic volcanism or syn-rift extensional tectonics. It is suggested that the geothermal anomaly in the southern Jornada del Muerto (approx. 125 to approx. 95 mWm(-2) results from some type of mass movement-heat transfer mechanism operating in the crust just below the elastic layer. This conclusion is consistent with the geologic and geophysical data which describe a thin crust, apparently devoid of features indicative of extensional-tectonics in the upper part of the lastic crust.

Exterior view of hipped roof with coffee processing structure in ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Exterior view of hipped roof with coffee processing structure in background, view towards the southwest - Pou Coffee Processing Structure, Casa No. 2, Highway 139, Kilometer 12, Maraguez, Ponce Municipio, PR

View towards east of interior wall structure with parts of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View towards east of interior wall structure with parts of coffee despulpadora in foreground - Finca Silem, Coffee Processing Structure No. 1, Highway 139, Kilometer 9.3, Maraguez, Ponce Municipio, PR

Providing Meaningful Learning for Students of the Sixth Grade of Middle School: a Study on the Moon Phases. (Breton Title: Propiciando Aprendizagem Significativa Para Alunos do Sexto Ano do Ensino Fundamental: um Estudo sobre as Fases da Lua.) Propiciando el Aprendizaje Significativo Para Alumnos del Sexto Nivel de la Educación General Básica: un Estudio sobre Las Fases de la Luna

NASA Astrophysics Data System (ADS)

Darroz, Luiz Marcelo; Samudio Pérez, Carlos Ariel; da Rosa, Cleci Werner; Heineck, Renato

2012-07-01

We relate in this article a didactic experience studying the moon phases with a group of middle school students of a private school of the municipality of Passo Fundo, RS. Based on David Ausubel's Meaningful Learning Theory, we have sought to develop a proposal following a didactic model which simulates the phases of the Moon, as based on the previous conceptions of the students. The signs of learning were evidenced by means of memory registries of the activity. From the obtained results we believe that the proposal achieved its goals, since the students were able to identify, differentiate and transfer the phenomenon of the moon phases to new contexts. Thus, it is concluded that a methodology focused on a meaningful content for the students is fundamental to the construction and genuine grasping of what is being learned. Neste artigo, relata-se uma experiência didática de estudo das fases da Lua com uma turma do 6° ano do Ensino Fundamental, de uma escola privada do município de Passo Fundo, RS. Tendo como fundamentação teórica a Teoria da Aprendizagem Significativa de David Ausubel, buscou-se desenvolver a proposta a partir de um modelo didático que simula as fases da Lua e com base nas concepções prévias dos estudantes. Os indícios da aprendizagem foram constatados através de registros de memórias da atividade. Pelos resultados apresentados, acredita-se que a proposta alcançou seus objetivos, uma vez que os estudantes conseguiram identificar, diferenciar e transferir o fenômeno das fases da Lua para novos contextos. Assim, conclui-se que uma metodologia com enfoque em um conteúdo significativo ao estudante é fundamental para a construção e compreensão genuína do que está sendo aprendido. En este artículo se relata una experiencia didáctica de estudio de las fases de la Luna con una clase de 6º año de la educación general básica de una escuela privada del municipio de Passo Fundo, RS. Teniendo como fundamentación teórica la Teor

Cambios históricos en el aporte terrígeno de la cuenca del Río de la Plata sobre la plataforma interna Uruguaya

NASA Astrophysics Data System (ADS)

Marrero, Analía; Tudurí, Adriana; Pérez, Laura; Cuña, Caroline; Muniz, Pablo; Lopes Figueira, Rubens; Michaelovitch de Mahiques, Michel; Alves de Lima Ferreira, Paulo; Pittauerová, Daniela; Hanebuth, Till; García Rodríguez, Felipe

2014-12-01

El Río de la Plata (RdlP) presenta significativas variaciones naturales (hidrodinámicas y oceanográficas) asociadas a diferentes condiciones climáticas. El propósito de este trabajo es inferir los cambios de aportes continentales de sedimentos y su relación con las variaciones hidrológicas del Río de la Plata, a través del análisis de proxies sedimentológicos y geoquímicos en testigos de sedimentos de la plataforma interna uruguaya que registran los últimos 100 años, aproximadamente. A partir de la datación por 210Pb de dos testigos de sedimentos (GeoB 13813-4 y BAR1) se reconstruyó la geocronología del ambiente, y se relacionó con datos de las forzantes climáticas Pacific Decadal Oscillation, El Niño/La Niña Southern Oscillation, Atlantic Multidecadal Oscillation, y las anomalías hidrológicas de los ríos Paraná y Uruguay. Los valores más positivos y estables del Southern Oscillation Index, los cuales corresponden a fases La Niña, se observan en el periodo correspondiente entre 1910-1970, respecto al resto de la serie, donde se aprecia una mayor variabilidad y una tendencia hacia valores más negativos (eventos El Niño). Se hicieron dendrogramas (clustering) jerárquicos para ambos testigos. Para el testigo GeoB 13813-4, se utilizó la relación Ca/Ti y la granulometría, mientras que para BAR1 se recurrió a variables granulométricas y la tasa de sedimentación. El mayor aporte continental hacia la región de la plataforma adyacente al Río de la Plata registrado a partir del año 1970, podría ser el factor principal de los agrupamientos observados en los clusters para ambos testigos. Las agrupaciones mostraron una diferenciación en la década de 1970, lo que estaría asociado al aumento de los caudales de los ríos Paraná y Uruguay, durante las últimas tres décadas del siglo XX. Por otra parte se observa que la granulometría del testigo BAR1 presentó un mayor tamaño de grano y más variabilidad que en el caso del testigo Geo

Prevalence of 185delAG and 5382insC mutations in BRCA1, and 6174delT in BRCA2 in women of Ashkenazi Jewish origin in southern Brazil

PubMed Central

Dillenburg, Crisle Vignol; Bandeira, Isabel Cristina; Tubino, Taiana Valente; Rossato, Luciana Grazziotin; Dias, Eleonora Souza; Bittelbrunn, Ana Cristina; Leistner-Segal, Sandra

2012-01-01

Certain mutations in BRCA1 and BRCA2 genes are frequent in the Ashkenazi Jewish population. Several factors contribute to this increased frequency, including consanguineous marriages and an event known as a “bottleneck”, which occurred in the past and caused a drastic reduction in the genetic variability of this population. Several studies were performed over the years in an attempt to elucidate the role of BRCA1 and BRCA2 genes in susceptibility to breast cancer. The aim of this study was to estimate the carrier frequency of certain common mutations in the BRCA1 (185delAG and 5382insC) and BRCA2 (6174delT) genes in an Ashkenazi Jewish population from Porto Alegre, Brazil. Molecular analyses were done by PCR followed by RFLP (ACRS). The carrier frequencies for BRCA1 185delAG and 5382insC were 0.78 and 0 respectively, and 0.4 for the BRCA2 6174deT mutation. These findings are similar to those of some prior studies but differ from others, possibly due to excluding individuals with a personal or family history of cancer. Our sample was drawn from the community group and included individuals with or without a family or personal history of cancer. Furthermore, increased dispersion among Ashkenazi subpopulations may be the result of strong genetic drift and/or admixture. It is therefore necessary to consider the effects of local admixture on the mismatch distributions of various Jewish populations. PMID:23055798

Prevalence of 185delAG and 5382insC mutations in BRCA1, and 6174delT in BRCA2 in women of Ashkenazi Jewish origin in southern Brazil.

PubMed

Dillenburg, Crisle Vignol; Bandeira, Isabel Cristina; Tubino, Taiana Valente; Rossato, Luciana Grazziotin; Dias, Eleonora Souza; Bittelbrunn, Ana Cristina; Leistner-Segal, Sandra

2012-07-01

Certain mutations in BRCA1 and BRCA2 genes are frequent in the Ashkenazi Jewish population. Several factors contribute to this increased frequency, including consanguineous marriages and an event known as a "bottleneck", which occurred in the past and caused a drastic reduction in the genetic variability of this population. Several studies were performed over the years in an attempt to elucidate the role of BRCA1 and BRCA2 genes in susceptibility to breast cancer. The aim of this study was to estimate the carrier frequency of certain common mutations in the BRCA1 (185delAG and 5382insC) and BRCA2 (6174delT) genes in an Ashkenazi Jewish population from Porto Alegre, Brazil. Molecular analyses were done by PCR followed by RFLP (ACRS). The carrier frequencies for BRCA1 185delAG and 5382insC were 0.78 and 0 respectively, and 0.4 for the BRCA2 6174deT mutation. These findings are similar to those of some prior studies but differ from others, possibly due to excluding individuals with a personal or family history of cancer. Our sample was drawn from the community group and included individuals with or without a family or personal history of cancer. Furthermore, increased dispersion among Ashkenazi subpopulations may be the result of strong genetic drift and/or admixture. It is therefore necessary to consider the effects of local admixture on the mismatch distributions of various Jewish populations.

High precision ages from the Torres del Paine Intrusion, Chile

NASA Astrophysics Data System (ADS)

Michel, J.; Baumgartner, L.; Cosca, M.; Ovtcharova, M.; Putlitz, B.; Schaltegger, U.

2006-12-01

The upper crustal bimodal Torres del Paine Intrusion, southern Chile, consists of the lower Paine-Mafic- Complex and the upper Paine-Granite. Geochronologically this bimodal complex is not well studied except for a few existing data from Halpern (1973) and Sanchez (2006). The aim of this study is to supplement the existing data and to constrain the age relations between the major magmatic pulses by applying high precision U-Pb dating on accessory zircons and 40Ar/39Ar-laser-step-heating-ages on biotites from the Torres del Paine Intrusion. The magmatic rocks from mafic complex are fine to medium-grained and vary in composition from quartz- monzonites to granodiorites and gabbros. Coarse-grained olivine gabbros have intruded these rocks in the west. The granitic body is represented by a peraluminous, biotite-orthoclase-granite and a more evolved leucocratic granite in the outer parts towards the host-rock. Field observations suggest a feeder-zone for the granite in the west and that the granite postdates the mafic complex. Two granite samples of the outermost margins in the Northeast and South were analyzed. The zircons were dated by precise isotope-dilution U-Pb techniques of chemically abraded single grains. The data are concordant within the analytical error and define weighted mean 206/238U ages of 12.59 ± 0.03 Ma and 12.58 ± 0.01 Ma for the two samples respectively. A 40Ar/39Ar-age for the second sample yield a date of 12.37 ± 0.11 Ma. Three 40Ar/39Ar -ages of biotites were obtained for rocks belonging to the mafic complex. A hbl-bio- granodiorite from the central part, approximately 150 m below the subhorizontal contact with the granite, gives an age of 12.81 ± 0.11 Ma. A hbl-bio-granodiorite and an olivine-gabbro west of the feeder-zone date at 12.42 ± 0.14 Ma and 12.49 ± 0.11 Ma, respectively. The obtained older age of 12.81 Ma for the granodiorite in the central part is consistent with structural relationships of brittle fracturing of the mafic

Dehydration-driven topotaxy in subduction zones

NASA Astrophysics Data System (ADS)

Padrón-Navarta, José Alberto; Tommasi, Andréa; Garrido, Carlos J.

2014-05-01

Mineral replacement reactions play a fundamental role in the chemistry and the strength of the lithosphere. When externally or internally derived fluids are present, interface-coupled dissolution-precipitation is the driving mechanism for such reactions [1]. One of the microstructural features of this process is a 3D arrangement of crystallographic axes across internal interfaces (topotaxy) between reactant and product phases. Dehydration reactions are a special case of mineral replacement reaction that generates a transient fluid-filled porosity. Among others, the dehydration serpentinite is of special relevance in subduction zones because of the amount of fluids involved (potentially up to 13 wt.%). Two topotatic relationships between olivine and antigorite (the serpentine mineral stable at high temperature and pressure) have been reported in partially hydrated mantle wedge xenoliths [2]. Therefore, if precursor antigorite serpentine has a strong crystallographic preferred orientation (CPO) its dehydration might result in prograde peridotite with a strong inherited CPO. However for predicting the importance of topotactic reactions for seismic anisotropy of subduction zones we also need to consider the crystallization orthopyroxene + chlorite in the prograde reaction and, more importantly, the fact that this dehydration reaction produces a transient porosity of ca. 20 % vol. that results in local fluctuations of strain during compaction and fluid migration. We address this issue by a microstructural comparison between the CPO developed in olivine, orthopyroxene and chlorite during high-pressure antigorite dehydration in piston cylinder experiments (at 750ºC and 20 kbar and 1000ºC and 30 kbar, 168 h) and that recorded in natural samples (Cerro del Almirez, Betic Cordillera, Spain). Experimentally developed CPOs are strong. Prograde minerals show a significant inheritance of the former antigorite foliation. Topotactic relations are dominated by (001)atg//(100)ol

The fate of metaclinopyroxenite during serpentinite subduction

NASA Astrophysics Data System (ADS)

Padrón-Navarta, J. A.; Gómez-Pugnaire, M. T.; López Sánchez-Vizcaíno, V.; Garrido, C. J.; Marchesi, C.

2012-04-01

Subduction of the partially hydrated section of the lithosphere is widely accepted as the major water carrier to sub-arc depths. Geodynamic models and geochemical mass balances assume that this section is comprised almost exclusively by the maximum hydrated counterpart of harzburgite, i.e. antigorite-serpentinite. The common wisdom gained through the study of oceanic and continental lithospheric sequences indicates, however, that this assumption is an oversimplification and that the widespread occurrence of other lithologies, such as clinopyroxenites, should not be disregarded. It is obvious, however, that the role of these non-conventional lithologies in the subduction factory will also depend on their ability to record hydration and dehydration reactions. Here we report the textural and mineral assemblage evolution of clinopyroxene-tremolite bearing serpentinite, metaclinopyroxenite bodies and associated diopside-chlorite schists interlayered in serpentinites from the Cerro del Almirez (Betic Cordillera, Spain), the only place known where the high-pressure antigorite dehydration front is preserved (Trommsdorff et al., 1998; Padrón-Navarta et al., 2011). Cpx-Tr serpentinite bodies are unevenly distributed at the decametric scale in the serpentinite sequence and occurs as isoclinally foliated layers. Tremolite in these rocks was formed by the reaction: antigorite + diopside = tremolite + olivine + fluid [1] These rocks have been traditionally interpreted as strongly dismembered clinopyroxenite layers finely intermixed at the cm-scale with serpentinite. The following observations regarding the relationship between metaclinopyroxenite bodies and diopside-chlorite schists are, however, against this hypothesis. Detailed observations in almost undeformed coarse grained (cm-sized) metaclinopyroxenite bodies show that incipient transformation of mantle clinopyroxene occurs along former exsolution lamellae by the reaction: clinopyroxene + fluid = diopside + chlorite [2

Planar view of northwest side of coffee processing structure No. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Planar view of northwest side of coffee processing structure No. 1, view towards the southeast - Finca Silem, Coffee Processing Structure No. 1, Highway 139, Kilometer 9.3, Maraguez, Ponce Municipio, PR

View of furnace feeding into the drum type coffee dryer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of furnace feeding into the drum type coffee dryer on second floor of structure, view towards southeast - Santaella Coffee Processing Site, Highway 139, Kilometer 10.6, Maraguez, Ponce Municipio, PR

75 FR 75663 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-06

... all corrections on the basis of appropriate documentation provided by the challenging entities and... about the CQR Program to the highest elected officials at all levels of state, Municipio, and Tribal...

E-ELT Site Chosen - World's Biggest Eye on the Sky to be Located on Armazones, Chile

NASA Astrophysics Data System (ADS)

2010-04-01

On 26 April 2010, the ESO Council selected Cerro Armazones as the baseline site for the planned 42-metre European Extremely Large Telescope (E-ELT). Cerro Armazones is a mountain at an altitude of 3060 metres in the central part of Chile's Atacama Desert, some 130 kilometres south of the town of Antofagasta and about 20 kilometres from Cerro Paranal, home of ESO's Very Large Telescope. "This is an important milestone that allows us to finalise the baseline design of this very ambitious project, which will vastly advance astronomical knowledge," says Tim de Zeeuw, ESO's Director General. "I thank the site selection team for the tremendous work they have done over the past few years." ESO's next step is to build a European extremely large optical/infrared telescope (E-ELT) with a primary mirror 42 metres in diameter. The E-ELT will be "the world's biggest eye on the sky" - the only such telescope in the world. ESO is drawing up detailed construction plans together with the community. The E-ELT will address many of the most pressing unsolved questions in astronomy, and may, eventually, revolutionise our perception of the Universe, much as Galileo's telescope did 400 years ago. The final go-ahead for construction is expected at the end of 2010, with the start of operations planned for 2018. The decision on the E-ELT site was taken by the ESO Council, which is the governing body of the Organisation composed of representatives of ESO's fourteen Member States, and is based on an extensive comparative meteorological investigation, which lasted several years. The majority of the data collected during the site selection campaigns will be made public in the course of the year 2010. Various factors needed to be considered in the site selection process. Obviously the "astronomical quality" of the atmosphere, for instance, the number of clear nights, the amount of water vapour, and the "stability" of the atmosphere (also known as seeing) played a crucial role. But other

Variation in mangrove forest structure and sediment characteristics in Bocas del Toro, Panama

USGS Publications Warehouse

Lovelock, C.E.; Feller, Ilka C.; McKee, K.L.; Thompson, R.

2005-01-01

Mangrove forest structure and sediment characteristics were examined in the extensive mangroves of Bocas del Toro, Republic of Panama. Forest structure was characterized to determine if spatial vegetation patterns were repeated over the Bocas del Toro landscape. Using a series of permanent plots and transects we found that the forests of Bocas del Toro were dominated by Rhizophora mangle with very few individuals of Avicennia germinans and Laguncularia racemosa. Despite this low species diversity, there was large variation in forest structure and in edaphic conditions (salinity, concentration of available phosphorus, Eh and sulphide concentration). Aboveground biomass varied 20-fold, from 6.8 Mg ha-1 in dwarf forests to 194.3 Mg ha-1 in the forests fringing the land. But variation in forest structure was predictable across the intertidal zone. There was a strong tree height gradient from seaward fringe (mean tree height 3.9 m), decreasing in stature in the interior dwarf forests (mean tree height 0.7 m), and increasing in stature in forests adjacent to the terrestrial forest (mean tree height 4.1 m). The predictable variation in forest structure emerges due to the complex interactions among edaphic and plant factors. Identifying predictable patterns in forest structure will aid in scaling up the ecosystem services provided by mangrove forests in coastal landscapes. Copyright 2005 College of Arts and Sciences.

CHEK2*1100delC homozygosity is associated with a high breast cancer risk in women.

PubMed

Adank, Muriel A; Jonker, Marianne A; Kluijt, Irma; van Mil, Saskia E; Oldenburg, Rogier A; Mooi, Wolter J; Hogervorst, Frans B L; van den Ouweland, Ans M W; Gille, Johan J P; Schmidt, Marjanka K; van der Vaart, Aad W; Meijers-Heijboer, Hanne; Waisfisz, Quinten

2011-12-01

Mutations in the CHEK2 gene confer a moderately increased breast cancer risk. The risk for female carriers of the CHEK2*1100delC mutation is twofold increased. Breast cancer risk for carrier women is higher in a familial breast cancer setting which is due to coinheritance of additional genetic risk factors. This study investigated the occurrence of homozygosity for the CHEK2*1100delC allele among familial breast cancer cases and the associated breast cancer risk. Homozygosity for the CHEK2*1100delC allele was identified in 8/2554 Dutch independent familial non-BRCA1/2 breast cancer cases. The genotype relative risk for breast cancer of homozygous and heterozygous familial breast cancer cases was 101.34 (95% CI 4.47 to 121 000) and 4.04 (95% CI 0.88 to 21.0), respectively. Female homozygotes appeared to have a greater than twofold increased breast cancer risk compared to familial CHEK2*1100delC heterozygotes (p=0.044). These results and the occurrence of multiple primary tumours in 7/10 homozygotes indicate a high cancer risk in homozygous women from non-BRCA1/2 families. Intensive breast surveillance is therefore justified in these homozygous women. It is concluded that diagnostic testing for biallelic mutations in CHEK2 is indicated in non-BRCA1/2 breast cancer families, especially in populations with a relatively high prevalence of deleterious mutations in CHEK2.

Optimal time travel in the Gödel universe

NASA Astrophysics Data System (ADS)

Natário, José

2012-04-01

Using the theory of optimal rocket trajectories in general relativity, recently developed in Henriques and Natário (2011), we present a candidate for the minimum total integrated acceleration closed timelike curve in the Gödel universe, and give evidence for its minimality. The total integrated acceleration of this curve is lower than Malament's conjectured value (Malament 1984), as was already implicit in the work of Manchak (Gen. Relativ. Gravit. 51-60, 2011); however, Malament's conjecture does seem to hold for periodic closed timelike curves.

Salmonella species and serotypes isolated from farm animals, animal feed, sewage, and sludge in Saudi Arabia*

PubMed Central

Nabbut, N. H.; Barbour, E. K.; Al-Nakhli, H. M.

1982-01-01

A total of 264 salmonellae representing 65 different species and serotypes were isolated for the first time in Saudi Arabia, from various animal species, animal feed, sewage, and sludge. The six most frequently isolated Salmonella species or serotypes were: livingstone, concord, “S. schottmuelleri” (invalid), lille, S. typhimurium, and cerro. PMID:6983931

78 FR 74008 - Amendment of Class E Airspace; Del Rio, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-10

... Laughlin Air Force Base (AFB). The FAA is taking this action to enhance the safety and management of... at Laughlin AFB, Del Rio, TX. An additional segment to the north is needed to contain approach category E military aircraft conducting circling approaches to the airport, to retain the safety and...

From badge of pride to cause of stigma: combatting mal del pinto in Mexico.

PubMed

Carrillo, Ana María

2013-03-01

Mal del pinto is a dermatological disease characterized by discoloured patches of skin on the face and body. It has been present in what is now the territory of Mexico from before the Spanish conquest up to recent times. Though early concerns for mal del pinto as a public health problem can be traced back to the late 19th century, no campaign to combat the disease was undertaken until the second half of the 20th. Thanks to the effectiveness of treatment with penicillin, the fight against this illness--which was once assumed as a symbol of pride--enjoyed a broader acceptance among the population that other health campaigns. Copyright © 2013 Elsevier Ltd. All rights reserved.

Descripción del coronógrafo a ser instalado en Argentina (MICA)

NASA Astrophysics Data System (ADS)

Stenborg, G.; Francile, C.; Schwenn, R.; Epple, A.; Rovira, M.

El ``Coronógrafo de espejo para Argentina'' es un telescopio solar terrestre a ser colocado en el Observatorio Astronómico Félix Aguilar (El Leoncito), antes de finalizar 1996, como parte de un programa de ciencia bilateral entre Alemania y Argentina. Eclipses fotográficos de alta resolución han revelado que la corona solar es altamente estructurada y variable. De hecho, está contínuamente deformada y moldeada por los movimientos convectivos de los extremos de los arcos magnéticos en la fotosfera, estando, en muchas oportunidades, afectada por explosivas liberaciones de energía. MICA, en conjunción con otros telescopios solares espaciales y terrestres, tratará de contribuir al entendimiento de cuestiones fundamentales de la física solar. Entre ellas: cómo la corona está siendo calentada, dónde y cómo el viento solar es acelerado, qué causa los transitorios coronales, etc. Para ello investigará la distribución de los parámetros del plasma y su evolución con el tiempo, la estructura espacial de la corona en fina y gran escala, procesos que ocurren en los transitorios coronales y factores que los disparan, etc. Para responder a estas cuestiones MICA observará la atmósfera solar por sobre el limbo entre 1.1 y 2 radios solares aproximadamente, usando un nuevo tipo de sistema coronográfico que permite suprimir el brillo del disco solar suficientemente bien, tomando las imágenes con una cámara CCD de 1024x1024 pixels, codificada en 12 bits, pudiendo el mismo ser operado en forma remota. En la presente exposición describiremos las características del instrumento, cómo será controlado y qué esperamos observar basados en las imágenes obtenidas por los telescopios de similares características LASCO C1 a bordo del SOHO y PICO (ubicado en el Observatorio de Pic du Midi, Francia).

49. Aerial view of statehouse and San Cristobal, Fuerte El ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

49. Aerial view of statehouse and San Cristobal, Fuerte El Abanico, San Carlos ravelin and Atlantic Ocean in the background - Castillo de San Cristobal, Boulevard Norzagaray, San Juan, San Juan Municipio, PR

Planar view towards the southeast of the front of coffee ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Planar view towards the southeast of the front of coffee processing structure with the Santaella residence to the left - Santaella Coffee Processing Site, Highway 139, Kilometer 10.6, Maraguez, Ponce Municipio, PR

View towards west from across Rio Cerrillos of coffee processing ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View towards west from across Rio Cerrillos of coffee processing structure (on left) with the Santaella residence (on right) - Santaella Coffee Processing Site, Highway 139, Kilometer 10.6, Maraguez, Ponce Municipio, PR

77 FR 4897 - Safety Zone; M/V Del Monte Live-Fire Gun Exercise, James River, Isle of Wight, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

...-AA00 Safety Zone; M/V Del Monte Live-Fire Gun Exercise, James River, Isle of Wight, VA AGENCY: Coast... provide for the safety of life on navigable waters during the live-fire gun exercises on the M/V Del Monte... associated with the live-fire gun exercise. DATES: This rule is effective in the CFR on February 1, 2012...