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1

TUDE DU RYTHME DES MISSIONS DE PARTICULES ALPHA DU POLONIUM Par JEAN BRENET,  

E-print Network

�TUDE DU RYTHME DES �MISSIONS DE PARTICULES ALPHA DU POLONIUM Par JEAN BRENET, Institut de Physique du Polonium (obtenus dans des conditions expérimentales différentes) ont été étudiés du point de vue

Boyer, Edmond

2

Interactions of diethylstilbestrol (DES) and DES analogs with membrane progestin receptor-alpha and the correlation with their nongenomic progestin activities.  

PubMed

Progestin induction of oocyte maturation (OM) in fish is a useful model for investigating endocrine disruption of nongenomic steroid actions. Although diethylstilbestrol (DES) analogs have been shown to mimic the actions of progestins to induce meiotic maturation of goldfish and zebrafish oocytes, their molecular mechanisms of action remain unclear. The ability of these endocrine-disrupting chemicals (EDCs) to interact with the progestin receptor mediating OM was investigated in receptor binding assays using plasma membranes from goldfish ovaries and breast cancer cells transfected with goldfish membrane progestin receptor (mPR)-alpha. Membranes prepared from both ovaries and mPRalpha-transfected cells showed high-affinity, saturable, displaceable, single binding sites specific for the goldfish maturation-inducing steroid, 17alpha,20beta-dihydroxy-4-pregnen-3-one (17,20beta-DHP). DES and DES analogs (dipropionate-DES and hexestrol), which induce OM in goldfish, bound to the receptor and caused concentration-dependent displacement of [3H]-17,20beta-DHP, whereas dimethyl ether-DES had no affinity for the receptor. Scatchard plot analysis of specific 17,20beta-DHP binding in the presence of different amounts of DES showed that DES binding is of the noncompetitive type. The activities of DES and DES analogs to induce meiotic maturation of goldfish oocytes were examined in an in vitro bioassay. Whereas a concentration-dependent induction of OM was observed in response to DES, dipropionate-DES, and hexestrol, dimethyl ether-DES did not show any OM-inducing activity. The close correspondence between binding of DES and its analogs to the mPRalpha protein and their OM-inducing activities suggests a mechanism of endocrine disruption mediated by binding to mPRalpha resulting in its activation, thereby mimicking the nongenomic action of the progestin 17,20beta-DHP. PMID:17446184

Tokumoto, Toshinobu; Tokumoto, Mika; Thomas, Peter

2007-07-01

3

Messung des Bremsvermögens von Pb 208 -Alpha-Rückstoßkernen in fester Materie  

Microsoft Academic Search

The stopping power of C, Ag and Au for Pb208 atoms recoiling from alpha decay with an energy of 169 keV was obtained by a time-of-flight technique yielding the energy distribution of these recoil atoms after their passage through thin foils. The theory ofBiersack (Thomas-Fermi-Firsov potential) and ofLindhard, Scharff andSchiøtt (Thomas-Fermi-Bohr potential) gives an adequate description of the results including

Dieter Marx

1966-01-01

4

Messung des Energieverlustes nicht-kanalisierter alpha-Teilchen in Transmission und Deutung mit Hilfe eines Durchschnittspotentials  

Microsoft Academic Search

The energy loss of alpha-particles transmitted through thin single crystals of silicon has been measured as a function of incidence angle near the (111) and (110) planes. Assuming an averaged continuum potential to be valid also for nonchanneled particles, the results of Monte Carlo calculations correspond with the experimental values of the averaged energy loss and energy straggling of the

Ernst Werner Rosendahl; Joachim Mönkediek

1978-01-01

5

Sur la nature des absorbeurs dans l'interpretation transactionnelle de la mecanique quantique  

NASA Astrophysics Data System (ADS)

L'interpretation transactionnelle de la mecanique quantique est l'une des plus recentes propositions de description des phenomenes du microcosme. En accord avec les predictions de la mecanique quantique standard, l'interpretation transactionnelle propose une alternative a celle de Copenhague. Son principal avantage est qu'elle permet de visualiser les mecanismes sous-jacents a l'echange d'energie, de quantite de mouvement ou d'autres quantites quantiques entre un emetteur et un absorbeur. Ces echanges sont le resultat, a l'instar de la theorie de l'absorbeur de Wheeler et Feynman, de l'utilisation autant d'ondes avancees que retardees. Bien que l'interpretation transactionnelle n'ait pas attire la plus grande attention scientifique, plusieurs critiques lui ont ete adressees. Dans les annees 1990, differentes experiences a mesure sans interaction ont ete concues. Depuis, il a ete avance que la version originale de l'interpretation transactionnelle pouvait difficilement rendre compte de ce type d'experience et meme qu'elle n'est pas compatible avec le concept d'univers quadridimensionnel. La recherche de ce memoire par article consiste a montrer que lorsque l'on utilise systematiquement l'interpretation transactionnelle en considerant la configuration totale des absorbeurs (incluant l'absorbeur universel), il n'est pas necessaire de faire appel a une hierarchie de transactions comme certains l'ont propose.

Boisvert, Jean-Sebastien

6

Alpha Thalassemia  

MedlinePLUS

Alpha Thalassemia ? Physicians often mistake alpha thalassemia trait for iron deficiency anemia and incorrectly prescribe iron supplements that have no effect on the anemia. Normal alpha globin genes ...

7

Role of the non-catalytic triad in alpha-amylases.  

E-print Network

??La triade non-catalytique est un motif strictement conservé des alpha-amylases chlorure-dépendentes qui est parfaitement superposable avec la triade catalytique des protéases à sérine active. Le… (more)

Marx, Jean-Claude

2007-01-01

8

Aufbau eines Experimentes zur Messung der Emissionswahrscheinlichkeit von Bremsstrahlung im alpha-Zerfall von Polonium-210.  

E-print Network

??Die Emissionswahrscheinlichkeit von Bremsstrahlung kann in den meisten Fällen sehr gut semi-klassisch beschrieben werden. Beim Alpha-Zerfall jedoch tunnelt das Alpha-Teilchen durch die Coulomb-Barriere des Kernes,… (more)

Boie, Hans-Hermann

9

L’influence du degré d’aversion à l’inégalité du décideur sur sa perception des inégalités intragroupes et intergroupes : une application de l’alpha décomposition aux salaires de la France entre 1995 et 2005  

Microsoft Academic Search

Nous proposons dans cette recherche de mettre en avant le rôle capital joué par les préférences du décideur sur sa perception des inégalités intragroupes et intergroupes. Une application réalisée à partir des salaires observés en France entre 1995 et 2005 révèle notamment de grands écarts de valeurs entre les différents indicateurs choisis pour évaluer l’évolution des disparités salariales sur la

Pauline MORNET; Françoise SEYTE; Michel TERRAZA

2012-01-01

10

Etude des phenomenes dynamiques ultrarapides et des caracteristiques impulsionnelles d'emission terahertz du supraconducteur YBCO  

NASA Astrophysics Data System (ADS)

Les premieres etudes d'antennes a base de supraconducteurs a haute temperature critique emettant une impulsion electromagnetique dont le contenu en frequence se situe dans le domaine terahertz remontent a 1996. Une antenne supraconductrice est formee d'un micro-pont d'une couche mince supraconductrice sur lequel un courant continu est applique. Un faisceau laser dans le visible est focalise sur le micro-pont et place le supraconducteur dans un etat hors-equilibre ou des paires sont brisees. Grace a la relaxation des quasiparticules en surplus et eventuellement de la reformation des paires supraconductrices, nous pouvons etudier la nature de la supraconductivite. L'analyse de la cinetique temporelle du champ electromagnetique emis par une telle antenne terahertz supraconductrice s'est averee utile pour decrire qualitativement les caracteristiques de celle-ci en fonction des parametres d'operation tels que le courant applique, la temperature et la puissance d'excitation. La comprehension de l'etat hors-equilibre est la cle pour comprendre le fonctionnement des antennes terahertz supraconductrices a haute temperature critique. Dans le but de comprendre ultimement cet etat hors-equilibre, nous avions besoin d'une methode et d'un modele pour extraire de facon plus systematique les proprietes intrinseques du materiau qui compose l'antenne terahertz a partir des caracteristiques d'emission de celle-ci. Nous avons developpe une procedure pour calibrer le spectrometre dans le domaine temporel en utilisant des antennes terahertz de GaAs bombarde aux protons H+ comme emetteur et detecteur. Une fois le montage calibre, nous y avons insere une antenne emettrice dipolaire de YBa 2Cu3O7-delta . Un modele avec des fonctions exponentielles de montee et de descente du signal est utilise pour lisser le spectre du champ electromagnetique de l'antenne de YBa 2Cu3O7-delta, ce qui nous permet d'extraire les proprietes intrinseques de ce dernier. Pour confirmer la validite du modele choisi, nous avons mesure les proprietes intrinseques du meme echantillon de YBa2Cu3O7- delta avec la technique pompe-visible et sonde-terahertz donnant, elle aussi, acces aux temps caracteristiques regissant l'evolution hors-equilibre de ce materiau. Dans le meilleur scenario, ces temps caracteristiques devraient correspondre a ceux evalues grace a la modelisation des antennes. Un bon controle des parametres de croissance des couches minces supraconductrices et de fabrication du dispositif nous a permis de realiser des antennes d'emission terahertz possedant d'excellentes caracteristiques en terme de largeur de bande d'emission (typiquement 3 THz) exploitables pour des applications de spectroscopie resolue dans le domaine temporel. Le modele developpe et retenu pour le lissage du spectre terahertz decrit bien les caracteristiques de l'antenne supraconductrice pour tous les parametres d'operation. Toutefois, le lien avec la technique pompe-sonde lors de la comparaison des proprietes intrinseques n'est pas direct malgre que les deux techniques montrent que le temps de relaxation des porteurs augmente pres de la temperature critique. Les donnees en pompe-sonde indiquent que la mesure du temps de relaxation depend de la frequence de la sonde, ce qui complique la correspondance des proprietes intrinseques entre les deux techniques. De meme, le temps de relaxation extrait a partir du spectre de l'antenne terahertz augmente en s'approchant de la temperature critique (T c) de YBa2Cu 3O7-delta. Le comportement en temperature du temps de relaxation correspond a une loi de puissance qui est fonction de l'inverse du gap supraconducteur avec un exposant 5 soit 1/Delta 5(T). Le travail presente dans cette these permet de mieux decrire les caracteristiques des antennes supraconductrices a haute temperature critique et de les relier aux proprietes intrinseques du materiau qui les compose. De plus, cette these presente les parametres a ajuster comme le courant applique, la puissance de la pompe, la temperature d'operation, etc, afin d'optimiser l'emission et les performances de ces

Savard, Stephane

11

Alpha-1 Antitrypsin Deficiency  

MedlinePLUS

... Liver > Liver Disease Information > Alpha-1 Antitrypsin Deficiency Alpha-1 Antitrypsin Deficiency Explore this section to learn more about alpha-1 antitrypsin deficiency, including a description of the ...

12

ALPHA OMEGA ALPHA National Honor Medical Society  

E-print Network

12/6/2012 1 ALPHA OMEGA ALPHA National Honor Medical Society www.alphaomegaalpha.org AA and Leadership The Alpha Omega Alpha honor medical society was organized in 1902 to "recognize and perpetuate Enter into a contract with patients and society Build a foundation of medical professionalism Define

13

Alpha-1 Antitrypsin Deficiency  

MedlinePLUS

... page from the NHLBI on Twitter. What Is Alpha-1 Antitrypsin Deficiency? Alpha-1 antitrypsin (an-tee-TRIP-sin) deficiency, or ... deficiency as it relates to lung disease. Overview Alpha-1 antitrypsin, also called AAT, is a protein ...

14

Liver and Alpha-1  

MedlinePLUS

... Resources CSL Behring Grifols The mission of the Alpha-1 Foundation is to provide the leadership and ... more information, visit: www.alpha-1foundation.org. The Alpha-1 Association is the leading national patient membership ...

15

Alpha One Foundation  

MedlinePLUS

What is Alpha-1? A lpha-1 Antitrypsin Deficiency (Alpha-1) is a genetic (inherited) condition – it is passed from parents to their children through their genes. Alpha-1 may result in serious lung disease in ...

16

Des Moines.  

ERIC Educational Resources Information Center

This document, intended for elementary students, contains articles and activities designed to acquaint young people with the history of Des Moines, Iowa. The articles are short, and new or difficult words are highlighted and defined for young readers. "The Raccoon River Indian Agency" discusses the archeological exploration of the indian…

Gore, Deborah, Ed.

1988-01-01

17

Alpha-1 Antitrypsin Test  

MedlinePLUS

... 1 Antitrypsin; ?1-antitrypsin Related tests: Protein Electrophoresis ; Total Protein ; Blood Gases ; Liver Panel At a Glance Test ... Alpha-1 antitrypsin measures the level of the protein AAT in blood. Alpha-1 antitrypsin ... antitrypsin genotype testing ( DNA testing) can ...

18

Emphysema and Alpha-1  

MedlinePLUS

... be carriers of the defective gene that causes Alpha-1. About 100,000 people in the U.S. ... of people with COPD may actually have undiagnosed Alpha-1 deficiency. © 2015 American Association for Respiratory Care

19

Alpha-1 antitrypsin deficiency  

MedlinePLUS

Alpha-1 antitrypsin (AAT) deficiency is a condition in which the body does not make enough of a protein ... Alpha-1 antitrypsin (AAT) is a type of protein called a protease inhibitor. AAT is made in the liver ...

20

LE JOURNAL DE PHYSIQUE DTERMINATION EXPRIMENTALE DE LA PERTE D'NERGIE, DES PARCOURS  

E-print Network

terbium, le thullium et l'or par des courbes de transmission avec mesures de courant. Les pertes d, terbium, thullium and gold by transmission curves with current measurements. Energy losses through a given des particules alpha dans le terbium et le thullium, ainsi que les pouvoirs d'arrêt; nous nous sommes

Paris-Sud XI, Université de

21

Rossi Alpha Method  

SciTech Connect

The Rossi Alpha Method has proved to be valuable for the determination of prompt neutron lifetimes in fissile assemblies having known reproduction numbers at or near delayed critical. This workshop report emphasizes the pioneering applications of the method by Dr. John D. Orndoff to fast-neutron critical assemblies at Los Alamos. The value of the method appears to disappear for subcritical systems where the Rossi-..alpha.. is no longer an ..alpha..-eigenvalue.

Hansen, G.E.

1985-01-01

22

Probl`eme de datation Les protocoles de communication  

E-print Network

'horloge du site de r´eception est en retard (suffisamment) sur celle du site de l'´emetteur Syst`emes et synchronisation des horloges locales : invariant max i=1..N (hi ) - min i=1..N (hi ) synchronisation d'horloges possible mais dans des contextes r´eseaux assurant une certaine qualit´e de service ou

Grigoras, .Romulus

23

Alpha-1 Health Tips  

MedlinePLUS

... risk factors. The biggest risk factor for lung disease is cigarette smoking. Any Alpha who smokes must stop! It is also important to avoid second-hand smoke and avoid inhaling irritants at ... available for Alphas with lung disease, this is only one part of the management ...

24

Alpha-1 Panniculitis  

MedlinePLUS

... of serum levels of alpha-1 antitrypsin (typically PI*ZZ) and others with only mild deficiency (typically PI*MZ). In one reported series of 26 patients with panniculitis and Alpha-1, 62 percent were PI*ZZ; 15 percent were PI*MZ; 8 percent ...

25

Event counting alpha detector  

DOEpatents

An electrostatic detector is disclosed for atmospheric radon or other weak sources of alpha radiation. In one embodiment, nested enclosures are insulated from one another, open at the top, and have a high voltage pin inside and insulated from the inside enclosure. An electric field is produced between the pin and the inside enclosure. Air ions produced by collision with alpha particles inside the decay volume defined by the inside enclosure are attracted to the pin and the inner enclosure. With low alpha concentrations, individual alpha events can be measured to indicate the presence of radon or other alpha radiation. In another embodiment, an electrical field is produced between parallel plates which are insulated from a single decay cavity enclosure. 6 figs.

Bolton, R.D.; MacArthur, D.W.

1996-08-27

26

Event counting alpha detector  

DOEpatents

An electrostatic detector for atmospheric radon or other weak sources of alpha radiation. In one embodiment, nested enclosures are insulated from one another, open at the top, and have a high voltage pin inside and insulated from the inside enclosure. An electric field is produced between the pin and the inside enclosure. Air ions produced by collision with alpha particles inside the decay volume defined by the inside enclosure are attracted to the pin and the inner enclosure. With low alpha concentrations, individual alpha events can be measured to indicate the presence of radon or other alpha radiation. In another embodiment, an electrical field is produced between parallel plates which are insulated from a single decay cavity enclosure.

Bolton, Richard D. (Los Alamos, NM); MacArthur, Duncan W. (Los Alamos, NM)

1996-01-01

27

Imaging alpha particle detector  

DOEpatents

A method and apparatus for detecting and imaging alpha particles sources is described. A conducting coated high voltage electrode (1) and a tungsten wire grid (2) constitute a diode configuration discharge generator for electrons dislodged from atoms or molecules located in between these electrodes when struck by alpha particles from a source (3) to be quantitatively or qualitatively analyzed. A thin polyester film window (4) allows the alpha particles to pass into the gas enclosure and the combination of the glass electrode, grid and window is light transparent such that the details of the source which is imaged with high resolution and sensitivity by the sparks produced can be observed visually as well. The source can be viewed directly, electronically counted or integrated over time using photographic methods. A significant increase in sensitivity over other alpha particle detectors is observed, and the device has very low sensitivity to gamma or beta emissions which might otherwise appear as noise on the alpha particle signal.

Anderson, David F. (Los Alamos, NM)

1985-01-01

28

Reexamination of the {alpha}-{alpha}''fishbone'' potential  

SciTech Connect

The fishbone potential of composite particles simulates the Pauli effect by nonlocal terms. We determine the {alpha}-{alpha} fishbone potential by simultaneously fitting to two-{alpha} resonance energies, experimental phase shifts, and three-{alpha} binding energies. We found that, essentially, a simple Gaussian can provide a good description of two-{alpha} and three-{alpha} experimental data without invoking three-body potentials.

Day, J. P.; McEwen, J. E.; Elhanafy, M.; Smith, E.; Woodhouse, R.; Papp, Z. [Department of Physics and Astronomy, California State University Long Beach, Long Beach, California (United States)

2011-09-15

29

Genetics Home Reference: Alpha thalassemia  

MedlinePLUS

... PubMed Recent literature OMIM Genetic disorder catalog Conditions > Alpha thalassemia On this page: Description Genetic changes Inheritance ... names Glossary definitions Reviewed August 2009 What is alpha thalassemia? Alpha thalassemia is a blood disorder that ...

30

Contribution aux Methodes Analytiques des Substances a L'aide de Faisceaux de Particules Chargees  

NASA Astrophysics Data System (ADS)

Nous avons vu les possibilites d'analyse par particules chargees des aerosols recueillis sur des filtres de type MILLIPORE. La meme technique a ete utilisee pour des filtres ayant servi a la filtration de l'eau du fleuve Saint-laurent. Deux techniques ont ete utilisees: (1) FAST (Forward Alpha Scattering Technique): pour analyser l'hydrogene, le carbone, l'oxygene et puis l'azote. Des alpha de 12 MeV ont ete utilises. (2) PIXE (Particle Induced X-ray Emission): pour analyser les elements moyens et lourds, dans ce cas des protons de 3 MeV ainsi que des ions d'argon de 1 et 1.6 MeV ont ete utilises. Les etudes ont montre que sous vide, la majorite des problemes proviennent des dommages causes par l'echauffement du a l'impact du faisceau sur le filtre. L'analyse quantitative par l'intermediaire du faisceau extrait peut presenter des difficultes en ce qui concerne les elements legers pour lesquels l'absorption des rayonnements caracteristiques dans l'atmosphere externe est importante. Les ions lourds se pretent mal aux analyses des aerosols du fait de leur limite de sensibilite. L'analyse directe de liquides par des protons est particulierement interessante puisqu'elle ne necessite aucune preparation prealable des echantillons. A cet effet, un programme de calcul de concentration des elements dans la solution a analyser a ete mis au point. Nous avons determine la limite de sensibilite de la methode PIXE pour les cibles minces (filtre) et pour le cas ou la matrice est de l'eau. Enfin, la technique FAST peut etre un complement de la technique PIXE.

Saidi, Abdelmajid

31

DTERMINATION DE L'NERGIE CINTIQUE MAXIMUM DES NEUTRONS MIS PAR LE GLUCINIUM BOMBARD PAR LES RAYONS a DU POLONIUM  

E-print Network

RAYONS a DU POLONIUM Par L. WINAND. Sommaire. 2014 L'auteur détermine les énergies cinétiques des noyaux envisagée. En admettant que c'est l'isotope 11 du Bore irradié par les particules alpha du Polonium qui est'énergie maximum observés. Ce noyau, sous l'action des rayons alpha du Polonium peut émettre, soit un proton, soit

Boyer, Edmond

32

Alpha Thalassemia (For Parents)  

MedlinePLUS

... of alpha thalassemia trait may want to seek genetic counseling if they're considering having children. If your ... For Parents MORE ON THIS TOPIC Genetic Testing Genetic Counseling All About Genetics Blood Blood Test: Hemoglobin Electrophoresis ...

33

Alpha Particle Diagnostic  

SciTech Connect

The study of burning plasmas is the next frontier in fusion energy research, and will be a major objective of the U.S. fusion program through U.S. collaboration with our international partners on the ITER Project. For DT magnetic fusion to be useful for energy production, it is essential that the energetic alpha particles produced by the fusion reactions be confined long enough to deposit a significant fraction of their initial ~3.5 MeV energy in the plasma before they are lost. Development of diagnostics to study the behavior of energetic confined alpha particles is a very important if not essential part of burning plasma research. Despite the clear need for these measurements, development of diagnostics to study confined the fast confined alphas to date has proven extremely difficult, and the available techniques remain for the most part unproven and with significant uncertainties. Research under this grant had the goal of developing diagnostics of fast confined alphas, primarily based on measurements of the neutron and ion tails resulting from alpha particle knock-on collisions with the plasma deuterium and tritium fuel ions. One of the strengths of this approach is the ability to measure the alphas in the hot plasma core where the interesting ignition physics will occur.

Fisher, Ray, K.

2009-05-13

34

Structure des ADN complmentaires des lactoprotines : application la recherche des gnes et leur localisation chromosomique  

E-print Network

Structure des ADN complémentaires des lactoprotéines : application à la recherche des gènes et à entrepris. 1) Construction de banques ovine et bovine d ADN complémentaires !ADNcJ. Sélection et identification des clones recombinants contenant les ADN complé- mentaires des ARNm des 6 principales

Paris-Sud XI, Université de

35

PHARMA -Rglement des examens et des jurys 2013-2014 Rglement des examens -Pharma 2013  

E-print Network

PHARMA - Règlement des examens et des jurys 2013-2014 Règlement des examens - Pharma 2013 1 missions décrites dans ce règlement. #12;PHARMA - Règlement des examens et des jurys 2013-2014 Règlement des examens - Pharma 2013 2 UNIVERSITE LIBRE DE BRUXELLES DEPARTEMENT ENSEIGNEMENT SERVICE D

Cerf, Nicolas

36

AlphaGalileo  

NSDL National Science Digital Library

AlphaGalileo is designed for science journalists, but anyone with an itch for breaking academic news will enjoy this research-rich site. Readers may browse by region, including Africa, Asia, Caribbean, Europe, Latin America, Middle East, North America, Oceania, and this Scout EditorâÂÂs favorite: Extraterrestrial. Next, try trawling the site by Science, Health, Society, Humanities, Arts, Applied Science, and Business for the latest illuminating research in each of these fields. AlphaGalileo also issues News Releases, usually five or six paragraphs long, that cover particularly interesting research findings. Best of all, since the Scout Report previously covered AlphaGalileo back in 2007, the site has dropped its membership requirements and visitors can browse more freely than ever.

37

[alpha]-Oxocarboxylic Acids  

ERIC Educational Resources Information Center

Several [alpha]-oxocarboxylic acids play key roles in metabolism in plants and animals. However, there are inconsistencies between the structures as commonly portrayed and the reported acid ionization constants, which result because the acids are predominantly hydrated in aqueous solution; that is, the predominant form is RC(OH)[subscript 2]COOH…

Kerber, Robert C.; Fernando, Marian S.

2010-01-01

38

[alpha-Neurotoxins and alpha-conotoxins--nicotinic cholinoreceptor blockers].  

PubMed

The review is devoted to the competitive blockers of different nicotinic acetylcholine receptors, alpha-neurotoxins from snake venoms, and alpha-conotoxins from marine snails of the Conidae family. The relationship between the structure and function of these toxins is discussed. Recent data on the mechanism of alpha-neurotoxin and alpha-conotoxin interaction with the nicotinic acetylcholine receptor are presented. PMID:10645484

Utkin, Iu N; Kasheverov, I E; Tsetlin, V I

1999-11-01

39

Expression des constantes de distorsion centrifuge des hexafluorures en fonction des frquences harmoniques.  

E-print Network

L-55 Expression des constantes de distorsion centrifuge des hexafluorures en fonction des de distorsion centrifuge des molécules XY6 en fonc- tion des fréquences harmoniques ; l for the centrifugal distortion constants as a function of harmonic frequencies ; application is made to SF6 and UF6. 4

Paris-Sud XI, Université de

40

ChemTeacher: Alpha Decay  

NSDL National Science Digital Library

ChemTeacher compiles background information, videos, articles, demonstrations, worksheets and activities for high school teachers to use in their classrooms. The Alpha Decay page includes resources for teaching students about the discovery and applications of alpha decay.

2011-01-01

41

DES Supernova Results  

NASA Astrophysics Data System (ADS)

The Dark Energy Survey Supernova program (DES SN) will discover approximately 3500 Type Ia supernovae with well-sampled multi-color light curves in the redshift range 0.2 < z < 1.2 over its five year duration. The large field of view and high z-band sensitivity of the Dark Energy Camera, combined with the precision photometry of DES and an improved handling of systematic uncertainties will allow DES SN to provide the strongest constraints on supernova cosmology to date. One of the main challenges for DES SN will be accurate classification of such a large number of faint transients. I will describe the unique spectroscopic follow-up strategy that we are employing, with emphasis on the 100 night, survey-status program at AAT which began in September. I will present preliminary supernova results obtained from the DES Science Verification period and the beginning of DES Year 1.

D'Andrea, Christopher; Dark Energy Survey, The

2014-01-01

42

Ethanol inhibits palmitoylation of G protein G alpha(s).  

PubMed

Neurobiological actions of ethanol have been linked to perturbations in cyclic AMP (cAMP)-dependent signaling processes. Chronic ethanol exposure leads to desensitization of cAMP production in response to physiological ligands (heterologous desensitization). Ethanol-induced alterations in neuronal expression of G proteins G(s) and G(i) have been invoked as a cause of heterologous desensitization. However, effects of ethanol on G protein expression vary considerably among different experimental protocols, various brain regions and diverse neuronal cell types. Dynamic palmitoylation of G protein alpha subunits is critical for membrane localization and protein-protein interactions, and represents a regulatory feature of G protein function. We studied the effect of ethanol on G alpha(s) palmitoylation. In NG108-15 rat neuroblastoma x glioma hybrid cells, acute exposure to pharmacologically relevant concentrations of ethanol (25-100 mm) inhibited basal and prostaglandin E1-stimulated incorporation of palmitate into G alpha(s). Exposure of NG108-15 cells to ethanol for 72 h induced a shift in G alpha(s) to its non-palmitoylated state, coincident with an inhibition of prostaglandin E1-induced cAMP production. Both parameters were restored following 24 h of ethanol withdrawal. Chronic ethanol exposure also induced the depalmitoylation of G alpha(s) in human embryonic kidney (HEK)293 cells that overexpress wild-type G alpha(s) and caused heterologous desensitization of adenylyl cyclase. By contrast, HEK293 cells that express a non-palmitoylated mutant of G alpha(s) were insensitive to heterologous desensitization after chronic ethanol exposure. In summary, the findings identify a novel effect of ethanol on post-translational lipid modification of G alpha(s), and represent a mechanism by which ethanol might affect adenylyl cyclase activity. PMID:15140191

Hallak, Hazem; Rubin, Raphael

2004-05-01

43

Médecine des voyages  

PubMed Central

Résumé Objectif Définir la pratique de la médecine des voyages, présenter les éléments fondamentaux d’une consultation complète préalable aux voyages à des voyageurs internationaux et aider à identifier les patients qu’il vaudrait mieux envoyer en consultation auprès de professionnels de la médecine des voyages. Sources des données Les lignes directrices et les recommandations sur la médecine des voyages et les maladies liées aux voyages publiées par les autorités sanitaires nationales et internationales ont fait l’objet d’un examen. Une recension des ouvrages connexes dans MEDLINE et EMBASE a aussi été effectuée. Message principal La médecine des voyages est une spécialité très dynamique qui se concentre sur les soins préventifs avant un voyage. Une évaluation exhaustive du risque pour chaque voyageur est essentielle pour mesurer avec exactitude les risques particuliers au voyageur, à son itinéraire et à sa destination et pour offrir des conseils sur les interventions les plus appropriées en gestion du risque afin de promouvoir la santé et prévenir les problèmes médicaux indésirables durant le voyage. Des vaccins peuvent aussi être nécessaires et doivent être personnalisés en fonction des antécédents d’immunisation du voyageur, de son itinéraire et du temps qu’il reste avant son départ. Conclusion La santé et la sécurité d’un voyageur dépendent du degré d’expertise du médecin qui offre le counseling préalable à son voyage et les vaccins, au besoin. On recommande à ceux qui donnent des conseils aux voyageurs d’être conscients de l’ampleur de cette responsabilité et de demander si possible une consultation auprès de professionnels de la médecine des voyages pour tous les voyageurs à risque élevé.

Aw, Brian; Boraston, Suni; Botten, David; Cherniwchan, Darin; Fazal, Hyder; Kelton, Timothy; Libman, Michael; Saldanha, Colin; Scappatura, Philip; Stowe, Brian

2014-01-01

44

EVALUATION DE LA DETECTION DES EMOTIONS, OPINONS OU SENTIMENTS Evaluation de la dtection des motions, des opinions ou des sentiments  

E-print Network

EVALUATION DE LA DETECTION DES EMOTIONS, OPINONS OU SENTIMENTS Evaluation de la détection des émotions, des opinions ou des sentiments : dictature de la majorité ou respect de la diversité d'opinion et analyse des sentiments sont généralement évalués par comparaison des réponses du système concerné

Paris-Sud XI, Université de

45

Amputation des quatre membres  

PubMed Central

Les auteurs présentent les cas d'amputation des quatre membres réalisée chez trois patients différents. Ce sont des amputations réalisées pour chaque patient au cours d'une seule hospitalisation et en un seul temps opératoire. Deux patients pour gangrène sèche infectée et un pour amputation traumatique des quatre membres. L'amputation d'urgence a été pratiquée en premier temps suivie de remodelage des moignons d'amputation en second temps. L’évolution de tous les patients a été bonne. PMID:25469177

Feruzi, Maruis Kitembo; Milindi, Cédrick Sangwa; Zabibu, Mireille Kakinga; Mulefu, Jules Panda; Katombe, Francois Tshilombo

2014-01-01

46

The alpha 21264 microprocessor  

Microsoft Academic Search

The third generation Alpha microprocessor from Compaq Computer Corporation (formerly Digital Equipment) is the 21264. This microprocessor can execute 2.0-2.4 billion instructions per second with a 500-600 MHz cycle time in a 0.35 um CMOS process, resulting in the industry-leading performance of 30+ SPECint95 and 58+ SPECfp95 in early system offerings. This paper focuses on the overall 21264 architecture, as

Richard E. Kessler

1999-01-01

47

Facult des arts et des sciences Dpartement de communication  

E-print Network

Faculté des arts et des sciences Département de communication Plans de cours cadre Cours des programmes de premier cycle en sciences de la communication Comité des études de premier cycle Adopté par l..................................................................................................................................3 COM 1150 Rédaction en communication 1

Parrott, Lael

48

Rpertoire des emplois en janvier 2011 des diplms de Master  

E-print Network

Répertoire des emplois en janvier 2011 des diplômés de Master Promotion 2008 Le répertoire des (CTU / UFR SLHS) - Education et promotion sanitaires et sociales, prévention des risques (CTU normes (UFR SLHS) - Sports et sociétés (UPFR sports) OFVE, 2011 - Page 2 #12;- Domaine Sciences, Santé

Jeanjean, Louis

49

Plan de cours Facult des arts et des sciences  

E-print Network

familiarisé avec les structures et les types d'organisation des Protistes, des Mycètes, des Algues et des eucaryotes Stramenopila (algues brunes, diatomées et oomycètes) 13 mai 3 Les protozoaires 14 mai 4 Les champignons, Les Lichens et Mycorhizes 20 mai 5 Myxomycota, Dyctiosteliomycota, Algues rouges et vertes 21 mai

Parrott, Lael

50

Politique de gestion des documents administratifs et des archives  

E-print Network

Politique de gestion des documents administratifs et des archives Préparation : Division de la gestion des documents administratifs et des archives Révision : Bureau du secrétaire général Entrée en vigueur : 15 février 2012 Approbation : (CA-2012-6) Cadre juridique : Loi sur les archives (L

51

Des cartographies de connaissances pour un pilotage des ressources humaines  

E-print Network

Des cartographies de connaissances pour un pilotage des ressources humaines et des processus RH'apport de la prospective : Mélanges en l'honneur de Luc Boyer (2010) xx-xxi" #12;Des cartographies de'organisation. Les cartographies de connaissances, parce qu'elles permettent l'identification et la représentation de

Paris-Sud XI, Université de

52

Eléments de comparaison internationale des patrimoines des ménages  

Microsoft Academic Search

[fre] A partir des bribes d'information existant sur les patrimoines de divers pays européens et des USA, une comparaison de la structure des patrimoines des inégalités de répartition et de leur évolution est tentée. Actifs financiers et actifs réels figurent de façon variable dans les patrimoines des différents pays. La Grande-Bretagne, avec une forte part d'actifs financiers, notamment de valeurs

Dominique Strauss-Kahn

1979-01-01

53

Background canceling surface alpha detector  

DOEpatents

A background canceling long range alpha detector which is capable of providing output proportional to both the alpha radiation emitted from a surface and to radioactive gas emanating from the surface. The detector operates by using an electrical field between first and second signal planes, an enclosure and the surface or substance to be monitored for alpha radiation. The first and second signal planes are maintained at the same voltage with respect to the electrically conductive enclosure, reducing leakage currents. In the presence of alpha radiation and radioactive gas decay, the signal from the first signal plane is proportional to both the surface alpha radiation and to the airborne radioactive gas, while the signal from the second signal plane is proportional only to the airborne radioactive gas. The difference between these two signals is proportional to the surface alpha radiation alone.

MacArthur, Duncan W. (Los Alamos, NM); Allander, Krag S. (Ojo Caliente, NM); Bounds, John A. (Los Alamos, NM)

1996-01-01

54

Archives participatives Au milieu des ralisations remarquables de mdiation numrique des bibliothques et des  

E-print Network

Archives participatives Au milieu des réalisations remarquables de médiation numérique des bibliothèques et des musées sur les médias sociaux, les services d'archives ont un positionnement relativement en revanche des projets ambitieux de crowdsourcing, d'« archives participatives » (voir encart

Paris-Sud XI, Université de

55

Long range alpha particle detector  

DOEpatents

An alpha particle detector capable of detecting alpha radiation from distant sources. In one embodiment, a high voltage is generated in a first electrically conductive mesh while a fan draws air containing air molecules ionized by alpha particles through an air passage and across a second electrically conductive mesh. The current in the second electrically conductive mesh can be detected and used for measurement or alarm. The detector can be used for area, personnel and equipment monitoring.

MacArthur, D.W.; Wolf, M.A.; McAtee, J.L.; Unruh, W.P.; Cucchiara, A.L.; Huchton, R.L.

1993-02-02

56

Long range alpha particle detector  

DOEpatents

An alpha particle detector capable of detecting alpha radiation from distant sources. In one embodiment, a high voltage is generated in a first electrically conductive mesh while a fan draws air containing air molecules ionized by alpha particles through an air passage and across a second electrically conductive mesh. The current in the second electrically conductive mesh can be detected and used for measurement or alarm. The detector can be used for area, personnel and equipment monitoring.

MacArthur, Duncan W. (Los Alamos, NM); Wolf, Michael A. (Los Alamos, NM); McAtee, James L. (Los Alamos, NM); Unruh, Wesley P. (Los Alamos, NM); Cucchiara, Alfred L. (Los Alamos, NM); Huchton, Roger L. (Los Alamos, NM)

1993-01-01

57

Alpha particle confinement in tokamaks  

SciTech Connect

An assessment of diffusive tokamak transport mechanisms of concern for alpha particles indicates that the ''stochastic regime'' is the only one which appears to pose a real danger for adequate alpha confinement. This fact, in conjunction with the threshold character of that mechanism, allows one to decide whether an alpha born at a given location will be lost or confined, according to a very simple criterion. Implementing this criterion numerically results in a new code for the assessment of alpha confinement, which is orders of magnitude faster than earlier codes used for this purpose. 13 refs., 3 figs., 1 tab.

White, R.B.; Mynick, H.E.

1988-11-01

58

Live! From 2-Alpha  

NSDL National Science Digital Library

This activity is one of several in which students are required to access and analyze actual data from NASA missions, including video "interviews" with real NASA scientists, to solve a mystery. In this mystery, students learn about the force of gravity and how scientists analyze data by studying the properties of different objects in space. Live! From 2-Alpha can be used to support instruction about forces and motion, origin and evolution of the universe, and the interaction of energy and matter. This activity is one of several in "Space Mysteries," a series of inquiry-driven, interactive Web explorations. Each Mystery in "Space Mysteries" is designed to teach at least one physical science concept (e.g. interactions of energy and matter, structures and properties of matter, energy, motion, or forces), and is accompanied by materials to be used by classroom teachers.

59

un cristal, des rseaux  

E-print Network

décrypter les matériaux du patrimoine. Le jaune chrome/plomb des tournesols de Van Gogh Certaines parties du tableau de van Gogh, « Fleurs dans un vase bleu » peint en 1887, ont changé de couleur au cours du temps/Université d'Anvers - Musée Van Gogh un cristal, des réseaux à l'upmc Voir l'article en ligne Site du

Arleo, Angelo

60

DFT CONFORMATIONAL STUDIES OF ALPHA-MALTOTRIOSE  

Technology Transfer Automated Retrieval System (TEKTRAN)

Recent DFT optimization studies on alpha-maltose improved our understanding of the preferred conformations of alpha-maltose and the present study extends these studies to alpha-maltotriose with three alpha-D-glucopyranose residues linked by two alpha-[1-4] bridges, denoted herein as DP-3's. Combina...

61

PHARMA -Rglement des examens et des jurys 2013-2014 Rglement des examens -Pharma juin 2013 1 / 16  

E-print Network

PHARMA - Règlement des examens et des jurys 2013-2014 Règlement des examens - Pharma juin 2013 1 missions décrites dans ce règlement. #12;PHARMA - Règlement des examens et des jurys 2013-2014 Règlement des examens - Pharma juin 2013 2 / 16 2 UNIVERSITE LIBRE DE BRUXELLES DEPARTEMENT ENSEIGNEMENT SERVICE

Cerf, Nicolas

62

PROCDURE DE DCLARATION DES ACCIDENTS, DES INCIDENTS ET DES SITUATIONS DANGEREUSES EN MILIEU DE TRAVAIL Novembre 2013  

E-print Network

PROC�DURE DE D�CLARATION DES ACCIDENTS, DES INCIDENTS ET DES SITUATIONS DANGEREUSES EN MILIEU DE de déclaration des accidents, des incidents et des situations dangereuses en milieu de travail. Ce, tout accident ou incident doit faire l'objet d'une déclaration officielle auprès de l'employeur. Selon

Meunier, Michel

63

Alpha particle emitters in medicine  

SciTech Connect

Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 ({sup 211}At) and natural bismuth-212 ({sup 212}Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 ({sup 223}Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs.

Fisher, D.R.

1989-09-01

64

EEG Alpha Power and Intelligence.  

ERIC Educational Resources Information Center

Tested whether alpha power in different sub-bands is selectively related to intelligence. For 74 Austrian subjects, the EEG was recorded during a resting session and 2 different intelligence tests were performed. Findings show a strong positive correlation between intelligence and alpha power. (SLD)

Doppelmayr, M.; Klimesch, W.; Stadler, W.; Pollhuber, D.; Heine, C.

2002-01-01

65

Determination of alpha_s from the QCD static energy  

E-print Network

We compare lattice data for the short-distance part of the static energy in 2+1 flavor quantum chromodynamics (QCD) with perturbative calculations, up to next-to-next-to-next-to leading-logarithmic accuracy. We show that perturbation theory describes very well the lattice data at short distances, and exploit this fact to obtain a determination of the product of the lattice scale r_0 with the QCD scale Lambda_{MS}. With the input of the value of r_0, this provides a determination of the strong coupling alpha_s at the typical distance scale of the lattice data. We obtain alpha_s(1.5 GeV)=0.326\\pm0.019, which provides a novel determination of alpha_s at low energy and with three-loop accuracy (including resummation of the leading ultrasoft logarithms). When this value is evolved to the Z-mass scale M_Z, it corresponds to alpha_s(M_Z)=0.1156^{+0.0021}_{-0.0022}.

Alexei Bazavov; Nora Brambilla; Xavier Garcia i Tormo; Peter Petreczky; Joan Soto; Antonio Vairo

2012-12-18

66

Learning about Alpha-1 Antitrypsin Deficiency (AATD)  

MedlinePLUS

... disease in children and adults. Alpha-1 Association Genetic Counseling Service [alpha1.org] The Alpha-1 Association Genetic Counseling Center provides toll-free, confidential genetic counseling to ...

67

Triplicated alpha-globin loci in humans.  

PubMed Central

We have identified 12 individuals who are heterozygous for a chromosome with three alpha-globin genes. We determined the presence of the third alpha-globin locus by restriction endonuclease digestion and hybridization with alpha-globin cDNA probes. The three alpha-globin loci resided in an elongated fragment on digestion with EcoRI, BamHI, and Xba I, and the third locus was present in an additional 3.7-kilobase fragment on digestion with Hpa I, Sac I, and Bgl II. The locations of the restriction sites are compatible with a nonhomologous crossover mechanism producing the triple alpha loci. The frequency of the triple alpha loci was 0.0036 in American blacks and less than 0.004 in Sardinians, but was higher in Greek Crypriots (0.05). Individuals with five alpha-globin genes (alpha alpha/alpha alpha alpha) apparently showed no clinical or hematologic abnormalities. Images PMID:6928643

Goossens, M; Dozy, A M; Embury, S H; Zachariades, Z; Hadjiminas, M G; Stamatoyannopoulos, G; Kan, Y W

1980-01-01

68

21 CFR 882.1610 - Alpha monitor.  

Code of Federal Regulations, 2011 CFR

... 2011-04-01 2011-04-01 false Alpha monitor. 882.1610 Section 882.1610...Neurological Diagnostic Devices § 882.1610 Alpha monitor. (a) Identification. An alpha monitor is a device with electrodes...

2011-04-01

69

Alpha-1 Antitrypsin Deficiency (Inherited Emphysema)  

MedlinePLUS

Alpha-1 Antitrypsin Deficiency Chronic obstructive pulmonary disease or COPD for short is a lung disease that ... disease. The inherited form of emphysema is called Alpha-1 Antitrypsin Deficiency or " Alpha-1 " for short. ...

70

How Is Alpha-1 Antitrypsin Deficiency Diagnosed?  

MedlinePLUS

... page from the NHLBI on Twitter. How Is Alpha-1 Antitrypsin Deficiency Diagnosed? Alpha-1 antitrypsin (AAT) deficiency usually is diagnosed after ... is. Rate This Content: Next >> October 11, 2011 Alpha-1 Antitrypsin Deficiency Clinical Trials Clinical trials are ...

71

Genetics Home Reference: Alpha-mannosidosis  

MedlinePLUS

... PubMed Recent literature OMIM Genetic disorder catalog Conditions > Alpha-mannosidosis On this page: Description Genetic changes Inheritance ... names Glossary definitions Reviewed May 2014 What is alpha-mannosidosis? Alpha-mannosidosis is a rare inherited disorder ...

72

How Is Alpha-1 Antitrypsin Deficiency Treated?  

MedlinePLUS

... page from the NHLBI on Twitter. How Is Alpha-1 Antitrypsin Deficiency Treated? Alpha-1 antitrypsin (AAT) deficiency has no cure, but ... deficiency. Rate This Content: Next >> October 11, 2011 Alpha-1 Antitrypsin Deficiency Clinical Trials Clinical trials are ...

73

What Is Alpha-1 Antitrypsin Deficiency?  

MedlinePLUS

... obstruction) to the ?ow of air. What causes Alpha-1? Alpha-1 is an inherited condition. Every ... two abnormal genes. Does everyone with two abnormal Alpha-1 genes develop disease? Not everyone who inherits ...

74

What Causes Alpha-1 Antitrypsin Deficiency?  

MedlinePLUS

... page from the NHLBI on Twitter. What Causes Alpha-1 Antitrypsin Deficiency? Alpha-1 antitrypsin (AAT) deficiency is an inherited disease. " ... deficiency. Rate This Content: Next >> October 11, 2011 Alpha-1 Antitrypsin Deficiency Clinical Trials Clinical trials are ...

75

Genetics Home Reference: 5-alpha reductase deficiency  

MedlinePLUS

... Recent literature OMIM Genetic disorder catalog Conditions > 5-alpha reductase deficiency On this page: Description Genetic changes ... Glossary definitions Reviewed April 2008 What is 5-alpha reductase deficiency? 5-alpha reductase deficiency is a ...

76

Genetics Home Reference: Alpha-1 antitrypsin deficiency  

MedlinePLUS

... PubMed Recent literature OMIM Genetic disorder catalog Conditions > Alpha-1 antitrypsin deficiency On this page: Description Genetic ... names Glossary definitions Reviewed January 2013 What is alpha-1 antitrypsin deficiency? Alpha-1 antitrypsin deficiency is ...

77

21 CFR 882.1610 - Alpha monitor.  

Code of Federal Regulations, 2010 CFR

... 2010-04-01 2010-04-01 false Alpha monitor. 882.1610 Section 882.1610...Neurological Diagnostic Devices § 882.1610 Alpha monitor. (a) Identification. An alpha monitor is a device with electrodes...

2010-04-01

78

Qualit des composts et des digestats Fabienne MULLER  

E-print Network

Qualité des composts et des digestats Fabienne MULLER Direction consommation durable et déchets organiques se construit, avec aujourd'hui le développement important de la méthanisation. Les composts actuellement produits, peuvent l'être avec des digestats ou non. Les quantités de compost produit ne cessent d

Boyer, Edmond

79

[Alpha-1-antitrypsin deficiency].  

PubMed

Alpha-1-antitrypsin (?1AT) deficiency is a genetic disorder that manifests as pulmonary emphysema and liver cirrhosis. ?1AT deficiency is the most common genetic cause of liver disease in children and also an underappreciated cause of liver disease in adults. The prevalence in the general population in Western Europe is approximately 1 in 2,000. The most common and severe deficiency allele is the Z variant (two alleles mutated). This variant is characterized by the accumulation of Z-?1AT polymers in the endoplasmic reticulum of hepatocytes leading to cell death and to a severe reduction of ?1AT in the serum. The latter results in a loss of its antiprotease activity and its ability to protect lung tissue. Thus far, there are only very limited therapeutic options in ?1AT deficiency. A more detailed understanding of the biology governing ?1AT biogenesis is required in order to identify new pharmacological agents and biomarkers. This review will present current knowledge on ?1AT deficiency and focus on recent discoveries and new strategies in the treatment of this disease. PMID:25311024

Bouchecareilh, Marion

2014-10-01

80

Measurement of $\\alpha_{s}$ with Radiative Hadronic Events  

E-print Network

Hadronic final states with a hard isolated photon are studied using data taken at centre-of-mass energies around the mass of the Z0 boson with the OPAL detector at LEP. The strong coupling alpha S is extracted by comparing data and QCD predictions for event shape observables at average reduced centre-of-mass energies ranging from 24 GeV to 78 GeV, and the energy dependence of alpha S is studied. Our results are consistent with the running of alpha S as predicted by QCD and show that within the uncertainties of our analysis event shapes in hadronic Z0 decays with hard and isolated photon radiation can be described by QCD at reduced centre-of-mass energies. Combining all values from different event shape observables and energies gives alpha S (Mz)=0.1182 pm 0.0015(stat.) pm 0.0101(syst.).

Abbiendi, G; Åkesson, P F; Alexander, G; Anagnostou, G; Anderson, K J; Asai, S; Axen, D; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, R J; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, S; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; Dallavalle, M; de Roeck, A; De Wolf, E A; Desch, K; Dienes, B; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, F; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, J; Gruwé, M; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Herten, G; Heuer, R D; Hill, J C; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, D; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krasznahorkays, A Jr; Krieger, P; Von Krogh, J; Kühl, T; Kupper, M; Lafferty, G D; Landsman, H; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Mashimo, T; Mättig, P; McKenna, J; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Pooth, O; Przybycien, M; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rossi, A M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schiecks, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, J; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

2008-01-01

81

Treatment of recurrent genital herpes with interferon alpha-2alpha.  

PubMed

The purpose of the present study was to evaluate the efficacy and safety of parenteral administration of interferon alpha-2alpha in the treatment of recurrent herpes genitalis. A total of 97 patients (66 males, 31 females, mean age 34.86 +/-16.74 years), who had at least five recurrences of genital herpes during the previous 12 months, participated in a prospective open study on the effects of treatment with interferon alpha-2alpha (Roferon-A; Roche). The patients were treated with interferon alpha-2alpha (3 x 10(6) IU) by subcutaneous injection, three times weekly for 4 weeks, and the same schedule was repeated after 3 and 6 months. All patients were asymptomatic at the start of the study. After initiation of treatment, all patients reported to the clinic every 3 months for 2 years (the males were submitted to peoscopy and the females to Pap test and colposcopy) at the time of their recurrences. Comparison was made of the number of recurrences, duration of lesions, duration and severity of pain, and itching and burning. Prophylactic administration of interferon alpha-2alpha prevented recurrences of genital herpes virus infection in 51 patients (20 males and 31 females). Interferon administration shortened the healing time from 8.5 days before treatment to 2.5 days after treatment (p < 0.001). There was a significant reduction in the number of recurrences during the study period, from 7.46 before treatment to 2.64 after treatment (p < 0.001). On the basis of the overall efficacy and adverse effects, this regimen may be of value in the routine treatment of recurrent herpes. PMID:9692344

Cardamakis, E; Relakis, K; Kotoulas, I G; Michopoulos, J; Metallinos, K; Mantouvalos, H; Tzingounis, V

1998-01-01

82

Simvastatin inhibits Staphylococcus aureus alpha toxin mediated polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction  

Microsoft Academic Search

Zusammenfassung Simvastatin, ein HMG-CoA-Reduktase-Inhibitor, wird im klinischen Alltag zur Senkung des Cholesterin-Spiegels eingesetzt. Darüber hinaus berichteten aktuelle Studien über protektive Eigenschaften von Statinen unter inflammatorischen Bedingungen. In dieser Studie wurden die Effekte von Simvastatin auf die Leukozyten-vermittelte Schädigung nach Stimulation mit Staphylococcus aureus alpha-Toxin untersucht. Aortale Gefäßsegmente von Ratten, vorbehandelt mit NaCl oder Simvastatin (100 µg\\/kg) intraperitoneal appliziert, wurden isoliert.

U. Buerke; M. Ruß; H. Schmidt; R. Prondzinsky; U. Sibelius; U. Grandel; F. Grimminger; W. Seeger; K. Werdan; M. Buerke

2005-01-01

83

La biogenèse des mélanosomes  

PubMed Central

Les mélanocytes situés à la base de l’épiderme produisent des mélanosomes qui sont transférés aux kératinocytes pour assurer la pigmentation de l’épiderme et sa photoprotection contre les rayons ultraviolets. Les mélanosomes, organites apparentés aux lysosomes, sont le lieu de synthèse et de stockage d’un pigment, la mélanine. Leur formation dépend de protéines mélanosomales qui transitent par les voies de biosynthèse et d’endocytose et exploitent les mécanismes moléculaires du trafic intracellulaire. Les acteurs moléculaires impliqués dans le transport des protéines mélanosomales et la biogenèse des mélanosomes sont la cible de mutations dans des maladies génétiques accompagnées d’hypopigmentation comme l’albinisme et les maladies lysosomales. Les études menées sur les mélanocytes issus de souris modèles de ces maladies permettent de comprendre certaines des étapes-clés de la mélanogenèse ainsi que les dysfonctionnements associés à ces pathologies. De plus, décrypter la mélanogenèse facilite également la compréhension d’autres processus physiologiques, comme l’illustrent les similitudes inattendues avec l’amyloïdogenèse dans les maladies neurodégénératives. PMID:21382323

Delevoye, Cédric; Giordano, Francesca; van Niel, Guillaume; Raposo, Graça

2012-01-01

84

Septembre 2012 Paludisme : des moustiques  

E-print Network

pulvérisations intra domiciliaires d'autres insecticides, les carbamates. Ces derniers agissent différemment au aux pyré- thrinoïdes et pulvérisé des carbamates à l'intérieur des habitations, les scientifiques ont

85

NOTE TECHNIQUE RECHERCHE DES SALMONELLA  

E-print Network

NOTE TECHNIQUE RECHERCHE DES SALMONELLA PAR IMMUNOFLUORESCENCE M. CATSARAS J. ANANI Laboratoire Salmonella, 366 prélèvements, dans 125 boucheries, pour lesquels nous avons comparé les techniques d, dus à des coliformes. Ses avantages et ses inconvénients pour la recherche des Salmonella sont

Paris-Sud XI, Université de

86

Die pharmakologische Wirkung des Ephedrins  

Microsoft Academic Search

Zusammenfassung 1.Die pharmakologische Wirkung des Ephedrins wurde zu analysieren versucht durch Studium der Beeinflussung des Blutdrucks, der Herzaktion und der Gefäße, des Effekts am Atemzentrum und an den Bronchien, der Wirkung auf die Pupillenweite, auf den Darm und den Uterus, auf die Sekretion verschiedener Drüsen und den Blutzuckerspiegel.2.Es wurden folgende Wirkungen gefunden: Der Blutdruck wird erhöht durch kleine Dosen, erniedrigt

H. Kreitmair

1927-01-01

87

Behandlung der Pseudarthrosen des Beckens  

Microsoft Academic Search

Pseudarthrosen des Beckenringes sind selten. Leitsymptom ist der chronische belastungsabhängige Schmerz des Beckenrings. Es muss überprüft werden, ob der Symptomenkomplex durch eine Pseudarthrose, durch eine posttraumatische Fehlstellung oder durch die Kombination von beiden verursacht ist. Diagnostisch wichtig sind die körperliche Untersuchung des ausgezogenen Patienten, Provokationstests, Röntgen (Beckenübersichts-, Inlet-, Outlet-, Ala- und Obturatoraufnahme) sowie die für die Analyse von Fehlstellungen, Instabilitäten

I. Marintschev; T. Mückley; F. Mendler; G. O. Hofmann

2005-01-01

88

Échantillonnage des gisements kimberlitiques à partir des microdiamants : Application à l'estimation des ressources récupérables.  

E-print Network

??La prédiction des ressources récupérables d'un gisement kimberlitique passe par l'estimation de la loi en taille des diamants commercialisables qu'il contient. Cette estimation repose traditionnellement… (more)

Ferreira, Johannes

2013-01-01

89

Facult des arts et des sciences cole de bibliothconomie et des sciences de l'information  

E-print Network

Faculté des arts et des sciences �cole de bibliothéconomie et des sciences de l'information COMMUNIQU� POUR DIFFUSION IMM�DIATE Aïda Chebbi, nouvelle docteure en sciences de l'information Montréal, le 26 février 2013 - L'�cole de bibliothéconomie et des sciences de l'information (EBSI) de l

Parrott, Lael

90

Facult des arts et des sciences cole de bibliothconomie et des sciences de l'information  

E-print Network

Faculté des arts et des sciences �cole de bibliothéconomie et des sciences de l'information POURQ. Montréal, le 17 octobre 2014 -- L'�cole de bibliothéconomie et des sciences de l'information (EBSI) de l aux missions de BAnQ. Madame Majela Guzmán Gómez réalise actuellement son doctorat en sciences de l'information

Parrott, Lael

91

Facult des arts et des sciences cole de bibliothconomie et des sciences de l'information  

E-print Network

Faculté des arts et des sciences �cole de bibliothéconomie et des sciences de l'information POUR l'information à l'EBSI Montréal, le 18 février 2014 -- L'�cole de bibliothéconomie et des sciences première �cole d'été internationale de la Francophonie en sciences de l'information, du 2 au 11 juillet

Leclercq, Remi

92

Alpha Ori - Evidence for pulsation  

NASA Technical Reports Server (NTRS)

The study deals with a periodic modulation of the UV continuum and Mg II emission-line fluxes shown by the bright cool supergiant Alpha Orionis; this pulsation is identified with the supergiant's atmosphere. UV brightness is shown to occur near the time of maximum outflow velocity of the photosphere, while local minima in the UV continuum occur near the time of maximum infall velocity. Visible and UV observations of Alpha Ori since the beginning of the monitoring program with IUE are discussed.

Dupree, A. K.; Baliunas, S. L.; Hartmann, L.; Guinan, E. F.; Sonneborn, G.

1990-01-01

93

Selective binding of collagen subtypes by integrin alpha 1I, alpha 2I, and alpha 10I domains.  

PubMed

Four integrins, namely alpha(1)beta(1), alpha(2)beta(1), alpha(10)beta(1), and alpha(11)beta(1), form a special subclass of cell adhesion receptors. They are all collagen receptors, and they recognize their ligands with an inserted domain (I domain) in their alpha subunit. We have produced the human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. When alpha(10)I was tested together with the alpha(1)I and alpha(2)I domains, all three I domains seemed to have their own collagen binding preferences. The integrin alpha(2)I domain bound much better to fibrillar collagens (I-III) than to basement membrane type IV collagen or to beaded filament-forming type VI collagen. Integrin alpha(1)I had the opposite binding pattern. The integrin alpha(10)I domain was similar to the alpha(1)I domain in that it bound very well to collagen types IV and VI. Based on the previously published atomic structures of the alpha(1)I and alpha(2)I domains, we modeled the structure of the alpha(10)I domain. The comparison of the three I domains revealed similarities and differences that could potentially explain their functional differences. Mutations were introduced into the alphaI domains, and their binding to types I, IV, and VI collagen was tested. In the alpha(2)I domain, Asp-219 is one of the amino acids previously suggested to interact directly with type I collagen. The corresponding amino acid in both the alpha(1)I and alpha(10)I domains is oppositely charged (Arg-218). The mutation D219R in the alpha(2)I domain changed the ligand binding pattern to resemble that of the alpha(1)I and alpha(10)I domains and, vice versa, the R218D mutation in the alpha(1)I and alpha(10)I domains created an alpha(2)I domain-like ligand binding pattern. Thus, all three collagen receptors appear to differ in their ability to recognize distinct collagen subtypes. The relatively small structural differences on their collagen binding surfaces may explain the functional specifics. PMID:11572855

Tulla, M; Pentikäinen, O T; Viitasalo, T; Käpylä, J; Impola, U; Nykvist, P; Nissinen, L; Johnson, M S; Heino, J

2001-12-21

94

des ateliers artistiques  

E-print Network

trompe-l'oeil... Des peaux brûlées en mal d'amour et de repères dans un monde ordinaire, étouffant'est-ce pas la même chose dans une histoire d'amour ? du 10 au 21 juin exposition de l'Atelier photo paris 6

95

Container structure of alpha alpha Lambda clusters in $_?^9$Be  

E-print Network

New concept of clustering is discussed in $\\Lambda$ hypernuclei using a new-type microscopic cluster model wave function, which has a structure that constituent clusters are confined in a container, whose size is a variational parameter and which we refer to as Hyper-Tohsaki-Horiuchi-Schuck-R\\"opke (Hyper-THSR) wave function. By using the Hyper-THSR wave function, $2\\alpha + \\Lambda$ cluster structure in ${^{9}_\\Lambda{\\rm Be}}$ is investigated. We show that full microscopic solutions in the $2\\alpha + \\Lambda$ cluster system, which are given as $2\\alpha + \\Lambda$ Brink-GCM wave functions, are almost perfectly reproduced by the single configurations of the Hyper-THSR wave function. The squared overlaps between the both wave functions are calculated to be $99.5$%, $99.4$%, and $97.7$% for $J^\\pi=0^+$, $2^+$, and $4^+$ states, respectively. We also simulate the structural change by adding the $\\Lambda$ particle, by varying the $\\Lambda N$ interaction artificially. As the increase of the $\\Lambda N$ interaction, the $\\Lambda$ particle gets to move more deeply inside the core and invokes strongly the spatial core shrinkage, and accordingly distinct localized $2\\alpha$ clusters appear in the nucleonic intrinsic density, though in ${^{8}{\\rm Be}}$ rather gaslike $2\\alpha$-cluster structure is shown. The origin of the localization is associated with the strong effect of Pauli principle. We conclude that the container picture of the $2\\alpha$ and $\\Lambda$ clusters is essential in understanding the cluster structure in ${^{9}_\\Lambda{\\rm Be}}$, in which the very compact spatial localization of clusters is shown in the density distribution.

Y. Funaki; T. Yamada; E. Hiyama; B. Zhou; K. Ikeda

2014-05-23

96

Quelques propriétés des théories de Jonsson  

Microsoft Academic Search

On étudie les propriétés des théories de Jonsson et des conditions nécessaires afin que des théories soient de Jonsson ; on caractérise les théories de Jonsson cosémantiques c’est-à-dire ayant un modèle homogène universel commun ainsi que certaines théories complètes contenant des théories de Jonsson. On donne des exemples de certaines situations.

Yerulan Mustafin

2002-01-01

97

fevrier 2012 Journes Francophones des Langages Applicatifs JFLA12 Separation des couleurs dans un -calcul bichrome  

E-print Network

AlligatorEggs3 cherche `a expliquer le -calcul `a des enfants. Pour cela il utilise la couleur pour relier des alligators affam´es et des oeufs afin de constituer des familles. La couleur sert `a expliciter les liaisons des variables dans les termes, des oeufs naissent de nouveaux alligators ou familles lors

Paris-Sud XI, Université de

98

Workshop on Precision Measurements of $\\alpha_s$  

SciTech Connect

These are the proceedings of the Workshop on Precision Measurements of {alpha}{sub s} held at the Max-Planck-Institute for Physics, Munich, February 9-11, 2011. The workshop explored in depth the determination of {alpha}{sub s}(m{sub Z}) in the {ovr MS} scheme from the key categories where high precision measurements are currently being made, including DIS and global PDF fits, {tau}-decays, electro-weak precision observables and Z-decays, event-shapes, and lattice QCD. These proceedings contain a short summary contribution from the speakers, as well as the lists of authors, conveners, participants, and talks.

Bethke, Siegfried; /Munich, Max Planck Inst.; Hoang, Andre H.; /Vienna U.; Kluth, Stefan; /Munich, Max Planck Inst.; Schieck, Jochen; /Munich U.; Stewart, Iain W.; Aoki, S.; Beneke, M.; Bethke, S.; Blumlein, J.; Brambilla, N.; Brodsky, S.; /MIT, LNS

2011-10-01

99

The Cycles of Alpha Centauri  

NASA Astrophysics Data System (ADS)

The main AB pair of the nearby Alpha Centauri triple system has an extensive X-ray history, covering three decades. Alpha Cen A (G2V) is a near twin of the Sun, with a similarly soft (1-2 MK) corona. Alpha Cen B (K1V) is more active than the Sun, with a generally harder X-ray spectrum. Here, spatially resolved measurements from ROSAT, XMM-Newton, and Chandra are compared on a common basis. In the combined time series, Alpha Cen B shows a distinct X-ray modulation with a period of about eight years and a factor of 5 cycle depth (the latter is similar to the Sun's). Alpha Cen A showed minimal variability 1995-2000, a decrease in the initial XMM epoch 2003-2005, and nearly constant behavior in the subsequent Chandra segment (late-2005 to present), although down a factor of 2 from the mid-1990's level. A remarkable ``smoking gun'' LETGS spectrum in mid-2007 emphasized that much of the coronal luminosity of solar-activity objects falls at longer wavelengths than recorded efficiently by contemporary instruments. This makes cycle depth strongly dependent on the energy bandpass of the measurement (here 0.2-2 keV), and complicates assessments of coronal heating requirements.

Ayres, Thomas

2009-09-01

100

Space Station alpha joint bearing  

NASA Technical Reports Server (NTRS)

Perhaps the most critical structural system aboard the Space Station is the Solar Alpha Rotary Joint which helps align the power generation system with the sun. The joint must provide structural support and controlled rotation to the outboard transverse booms as well as power and data transfer across the joint. The Solar Alpha Rotary Joint is composed of two transition sections and an integral, large diameter bearing. Alpha joint bearing design presents a particularly interesting problem because of its large size and need for high reliability, stiffness, and on orbit maintability. The discrete roller bearing developed is a novel refinement to cam follower technology. It offers thermal compensation and ease of on-orbit maintenance that are not found in conventional rolling element bearings. How the bearing design evolved is summarized. Driving requirements are reviewed, alternative concepts assessed, and the selected design is described.

Everman, Michael R.; Jones, P. Alan; Spencer, Porter A.

1987-01-01

101

Bremsstrahlung in {alpha} Decay Reexamined  

SciTech Connect

A high-statistics measurement of bremsstrahlung emitted in the {alpha} decay of {sup 210}Po has been performed, which allows us to follow the photon spectra up to energies of {approx}500 keV. The measured differential emission probability is in good agreement with our theoretical results obtained within the quasiclassical approximation as well as with the exact quantum mechanical calculation. It is shown that, due to the small effective electric dipole charge of the radiating system, a significant interference between the electric dipole and quadrupole contributions occurs, which is altering substantially the angular correlation between the {alpha} particle and the emitted photon.

Boie, H.; Scheit, H.; Jentschura, U. D.; Koeck, F.; Lauer, M.; Schwalm, D. [Max-Planck-Institut fuer Kernphysik, D-69117 Heidelberg (Germany); Milstein, A. I.; Terekhov, I. S. [Budker Institute of Nuclear Physics, 630090 Novosibirsk (Russian Federation)

2007-07-13

102

NACA Physicist Studying Alpha Rays  

NASA Technical Reports Server (NTRS)

NACA Physicits studying Alpha Rays in a continuous cloud chamber. A cloud chamber is used by Lewis scientists to obtain information aimed at minimizing undesirable effects of radiation on nuclear-powered aircraft components. Here, alpha particles from a polonium source emit in a flower-like pattern at the cloud chamber's center. The particles are made visible by means of alcohol vapor diffusing from an area at room temperature to an area at minus -78 deg. Centigrade. Nuclear-powered aircraft were never developed and aircraft nuclear propulsion systems were canceled in the early 1960s.

1957-01-01

103

Simulating the Lyman Alpha Forest  

E-print Network

In this paper we review the importance of the Lyman alpha forest as a probe of structure formation in the universe. We first discuss the statistics used to describe the Lyman alpha forest and the numerical techniques used to produce simulated spectra of the forest from a given cosmological model. We then discuss the physical picture of the absorbing structures that emerges from these numerical simulations. Finally, we comment on how two of the statistics, the slope of the column density distribution and the b parameter distribution, may be used to constrain competing cosmologies.

Marie E. Machacek; Greg L. Bryan; Peter Anninos; Avery Meiksin; Michael L. Norman

1998-08-04

104

alpha_s From the Lattice and Hadronic Tau Decays  

E-print Network

Until recently, determinations of alpha_s(M_Z) from hadronic tau decays and the analysis of short-distance-sensitive lattice observables yielded results which, though precise, were not in good agreement. I review new analyses that bring these into good agreement and provide some details on the source of the main changes in the tau decay analysis.

Kim Maltman

2009-06-26

105

Scattering of alpha particles by 22Ne  

Microsoft Academic Search

Differential cross sections at a few angles for 22Ne(alpha,alphai)22Ne are reported for alphai=alpha0, alpha1, and alpha2 mainly in 10 keV steps for 22alpha,alpha), 13.4<=Ealpha (MeV)<=20,8, elastic and inelastic (2+, 1.27 MeV and 4+, 3.36 MeV). Measured sigma(theta,Ealpha) at one or two angles.

C. A. Davis

1981-01-01

106

Detection and characterization of N-alpha-chloramines by electrospray tandem mass spectrometry.  

PubMed

Hypochlorous acid (HOCl) is a major product of activated neutrophils and may be important in antimicrobial activities of cells by oxidation or chlorination of susceptible amino acids. Three major peaks separated using C18 reverse phase-high-performance liquid chromatography RP-HPLC after incubation of leucine enkephalin (LeuEnk) with HOCl. Electrospray mass spectrometry showed masses of m/z 556.2, 590.2, and 624.4 corresponding to unmodified LeuEnk and peptides altered by addition of one or two chlorines (Cl). Formation of stable N-alpha-chloramines was indicated because the chlorinated peptides were readily reduced with the physiological reductants glutathione and ascorbic acid to LeuEnk (m/z 556.2) within 10 min. Sequence-specific ions observed in product ion spectra of single-charged monochlorinated and dichlorinated peptides were consistent with modification of the N-terminal amine. There was no evidence for chlorination of the Tyr aromatic ring in any spectra. Similar RP-HPLC profiles were obtained after oxidation of des-Tyr1-LeuEnk (GGFL) with the masses of the major products being m/z 393.3, 427.2, and 461.1. These were identified as unmodified GGFL, N-alpha-Cl-GGFL, and N-alpha-Cl2-GGFL based on comparison of tandem mass spectra. Oxidation of Met and formation of disulfide dimers was observed after incubation of either N-alpha-Cl-LeuEnk or N-alpha-Cl2-LeuEnk with a protein, indicating that both peptide N-alpha-chloramines were able to readily modify sulfur-containing amino acids within proteins. These data indicate initial formation of stable N-alpha-chorinated peptides after incubation with HOCl and suggest that N-alpha-chlorinated peptides may exist for some hours in the absence of physiological reducing agents or sulfur-containing amino acids. PMID:17537392

Raftery, Mark J

2007-07-15

107

Meet the Alpha-Pets.  

ERIC Educational Resources Information Center

"Alpha-Pets" are the focal point of an integrated, multidisciplinary curriculum. Each pet is featured for a week in a vocabulary-rich story and introduces related activities beginning with the featured letter, such as the four food groups during Freddie Fish's week or universe during Ulysses Unicorn's week. (MT)

Zitlaw, Jo Ann Bruce; Frank, Cheryl Standish

1985-01-01

108

Alpha Testing Escape from Diab  

Technology Transfer Automated Retrieval System (TEKTRAN)

Alpha testing was conducted of sessions 2 and 3 from Diab to assess whether the activities worked as expected, and whether children in the target ages enjoyed it. Data include both RA observations of child performance while playing the games and cognitive interview responses from the players after t...

109

Alpha proton x ray spectrometer  

NASA Technical Reports Server (NTRS)

Mars Pathfinder will carry an alpha-proton x ray spectrometer (APX) for the determination of the elemental chemical composition of Martian rocks and soils. The instrument will measure the concentration of all major and some minor elements, including C, N, and O at levels above typically 1 percent.

Rieder, Rudi; Waeke, H.; Economou, T.

1994-01-01

110

Geschichte des Widerstandes in Film und Fernsehen.  

E-print Network

??In der Diplomarbeit „Geschichte des Widerstandes in Film und Fernsehen“ wird die unterschiedliche Darstellungsweise des Stauffenberg-Attentats auf den „Führer“ Adolf Hitler vom 20. Juli 1944… (more)

Bauer, Marlies

2010-01-01

111

TIC et commerce lectronique : laboratoires de la libralisation des changes et des volutions des rgles  

E-print Network

1 TIC et commerce électronique : laboratoires de la libéralisation des échanges et des évolutions/Département Sciences Economiques et Sociales Les échanges internationaux de produits TIC et le commerce électroniques à terme à l'abolition des droits de douane pour les produits de la filière TIC et les échanges

Paris-Sud XI, Université de

112

Coexistence of {alpha}+{alpha}+n+n and {alpha}+t+t cluster structures in {sup 10}Be  

SciTech Connect

The coexistence of the {alpha}+{alpha}+n+n and {alpha}+t+t cluster structures in the excited states of {sup 10}Be has been discussed. In the previous analysis, all the low-lying states of {sup 10}Be were found to be well described by the motion of the two valence neutrons around two {alpha} clusters. However, the {alpha}+t+t cluster structure was found to coexist with the {alpha}+{alpha}+n+n structure around E{sub x}=15 MeV, close to the corresponding threshold. We have introduced a microscopic model to solve the coupling effect between these two configurations. The K=0 and K=1 states are generated from the {alpha}+t+t configurations due to the spin coupling of two triton clusters. The present case of {sup 10}Be is one of the few examples in which completely different configurations of triton-type ({alpha}+t+t three-center) and {alpha}-type ({alpha}+{alpha}+n+n two-center) clusters coexist in a single nucleus in the same energy region.

Itagaki, N. [Department of Physics, University of Tokyo, Hongo, 113-0033 Tokyo (Japan); Ito, M. [RIKEN Nishina Center, Wako, 351-0198 Saitama (Japan); Milin, M. [Department of Physics, University of Zagreb, HR-10000 Zagreb (Croatia); Hashimoto, T.; Ishiyama, H.; Miyatake, H. [Tokai Radioactive Ion Accelerator Complex, High Energy Accelerator Research Organization (KEK), Tokai, 319-1105 Ibaraki (Japan)

2008-06-15

113

Localisation des salles UFR SLHS : Facult des Lettres  

E-print Network

Promotion Formation Recherche des Sports 31 rue de l'épitaphe, 25000 Besançon IUT: Institut Universitaire de'Observatoire 25000 Besançon UFR ST : Faculté des Sciences 16 route de Gray, 25000 Besançon UPFR Sports : Unité de

Jeanjean, Louis

114

UNIVERSIT DE NANTES FACULT DES SCIENCES ET DES TECHNIQUES  

E-print Network

épineux des DSSC. J'associe aussi à ces remerciements Yann Pellegrin et Errol Blart, qui ont été des personnes très sympathiques à rencontrer et qui ont rendus les réunions "DSSC" plus agréables, entre autre

Paris-Sud XI, Université de

115

Facult des arts et des sciences cole de bibliothconomie et des sciences de l'information  

E-print Network

Faculté des arts et des sciences �cole de bibliothéconomie et des sciences de l'information -- L'�cole de bibliothéconomie et des sciences de l'information (EBSI) de l'Université de Montréal est destinée aux étudiants de doctorat ou de maîtrise en sciences de l'information qui démontrent un intérêt

Parrott, Lael

116

Aversive Situational Effects on Alpha Feedback Training  

ERIC Educational Resources Information Center

Anticipation of electric shock did not depress alpha activity in a feedback situation. Contrary to previous reports, a reduction in alpha activity is not a necessary consequence of apprehension or heightened arousal. (Author)

Orne, Martin T.; Paskeqitz, David A.

1974-01-01

117

Q (Alpha) Function and Squeezing Effect  

NASA Technical Reports Server (NTRS)

The relation of squeezing and Q(alpha) function is discussed in this paper. By means of Q function, the squeezing of field with gaussian Q(alpha) function or negative P(a)function is also discussed in detail.

Yunjie, Xia; Xianghe, Kong; Kezhu, Yan; Wanping, Chen

1996-01-01

118

Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism.  

PubMed

Failure of the testes to descend into the scrotum (cryptorchidism) is one of the most common birth defects in humans. In utero exposure to estrogens, such as 17beta-estradiol (E2) or the synthetic estrogen diethylstilbestrol (DES), down-regulates insulin-like 3 (Insl3) expression in embryonic Leydig cells, which in turn results in cryptorchidism in mice. To identify the molecular mechanism whereby xenoestrogens block Insl3 gene transcription, we performed a microarray analysis of wild-type or estrogen receptor (ER) alpha-mutant testes exposed in utero to pharmacological doses of E2 or DES. Six and 31 genes were respectively down-regulated and up-regulated by estrogen exposure (> or =4-fold). All six genes down-regulated by estrogen exposure, including Insl3 and the steroidogenic genes steroidogenic acute regulatory protein and cytochrome P450 17alpha-hydroxylase/17,20-lyase, were done so by an ERalpha-dependent mechanism. In contrast, up-regulation was mediated either by ERalpha for 12 genes or by an independent mechanism for the 19 remaining genes. Finally, we show that Insl3 gene expression and testicular descent were not affected by in utero exposure to E2 or DES in ERalpha mutant mice, whereas absence of ERbeta did not influence the effect of these estrogens. Collectively, these data demonstrate that xenoestrogens inhibit the endocrine functions of fetal Leydig cells through an ERalpha-dependent mechanism. PMID:17673513

Cederroth, Christopher R; Schaad, Olivier; Descombes, Patrick; Chambon, Pierre; Vassalli, Jean-Dominique; Nef, Serge

2007-11-01

119

Association of actin with alpha crystallins  

NASA Technical Reports Server (NTRS)

The alpha crystallins are cytosolic proteins that co-localize and co-purify with actin-containing microfilaments. Affinity column chromatography employing both covalently-coupled actin or alpha crystallin was used to demonstrate specific and saturable binding of actin with alpha crystallin. This conclusion was confirmed by direct visualization of alpha aggregates bound to actin polymerized in vitro. The significance of this interaction in relation to the functional properties of these two polypeptides will be discussed.

Gopalakrishnan, S.; Boyle, D.; Takemoto, L.; Spooner, B. S. (Principal Investigator)

1993-01-01

120

AlphaSort: A RISC Machine Sort  

Microsoft Academic Search

A new sort algorithm, called AlphaSort, demonstrates that commodity processors and disks can handle commercial batch workloads. Using Alpha AXP processors, commodi~ memory, and arrays of SCSI disks, AlphaSort runs the industry-standard sort benchmark in seven seconds. This beats the best published record on a 32-cpu 32-disk Hypercube by 8:1. On another benchmark, AlphaSort sorted more than a gigabyte in

Chris Nyberg; Tom Barclay; Zarka Cvetanovic; Jim Gray; David B. Lomet

1994-01-01

121

Unfolding domains of recombinant fusion alpha alpha-tropomyosin.  

PubMed Central

The thermal unfolding of the coiled-coil alpha-helix of recombinant alpha alpha-tropomyosin from rat striated muscle containing an additional 80-residue peptide of influenza virus NS1 protein at the N-terminus (fusion-tropomyosin) was studied with circular dichroism and fluorescence techniques. Fusion-tropomyosin unfolded in four cooperative transitions: (1) a pretransition starting at 35 degrees C involving the middle of the molecule; (2) a major transition at 46 degrees C involving no more than 36% of the helix from the C-terminus; (3) a major transition at 56 degrees C involving about 46% of the helix from the N-terminus; and (4) a transition from the nonhelical fusion domain at about 70 degrees C. Rabbit skeletal muscle tropomyosin, which lacks the fusion peptide but has the same tropomyosin sequence, does not exhibit the 56 degrees C or 70 degrees C transition. The very stable fusion unfolding domain of fusion-tropomyosin, which appears in electron micrographs as a globular structural domain at one end of the tropomyosin rod, acts as a cross-link to stabilize the adjacent N-terminal domain. The least stable middle of the molecule, when unfolded, acts as a boundary to allow the independent unfolding of the C-terminal domain at 46 degrees C from the stabilized N-terminal unfolding domain at 56 degrees C. Thus, strong localized interchain interactions in coiled-coil molecules can increase the stability of neighboring domains. PMID:1303750

Ishii, Y.; Hitchcock-DeGregori, S.; Mabuchi, K.; Lehrer, S. S.

1992-01-01

122

Analogs of alpha-conotoxin MII are selective for alpha6-containing nicotinic acetylcholine receptors.  

PubMed

Neuronal nicotinic acetylcholine receptors (nAChRs) both mediate direct cholinergic synaptic transmission and modulate synaptic transmission by other neurotransmitters. Novel ligands are needed as probes to discriminate among structurally related nAChR subtypes. Alpha-conotoxin MII, a selective ligand that discriminates among a variety of nAChR subtypes, fails to discriminate well between some subtypes containing the closely related alpha3 and alpha6 subunits. Structure-function analysis of alpha-conotoxin MII was performed in an attempt to generate analogs with preference for alpha6-containing [alpha6(*) (asterisks indicate the possible presence of additional subunits)] nAChRs. Alanine substitution resulted in several analogs with decreased activity at alpha3(*) versus alpha6(*) nAChRs heterologously expressed in Xenopus laevis oocytes. From the initial analogs, a series of mutations with two alanine substitutions was synthesized. Substitution at His9 and Leu15 (MII[H9A;L15A]) resulted in a 29-fold lower IC(50) at alpha6beta4 versus alpha3beta4 nAChRs. The peptide had a 590-fold lower IC(50) for alpha6/alpha3beta2 versus alpha3beta2 and a 2020-fold lower IC(50) for alpha6/alpha3beta2beta3 versus alpha3beta2 nAChRs. MII[H9A;L15A] had little or no activity at alpha2beta2, alpha2beta4, alpha3beta4, alpha4beta2, alpha4beta4, and alpha7 nAChRs. Functional block by MII[H9A;L15A] of rat alpha6/alpha3beta2beta3 nAChRs (IC(50) = 2.4 nM) correlated well with the inhibition constant of MII[H9A;L15A] for [(125)I]alpha-conotoxin MII binding to putative alpha6beta2(*) nAChRs in mouse brain homogenates (K(i) = 3.3 nM). Thus, structure-function analysis of alpha-conotoxin MII enabled the creation of novel selective antagonists for discriminating among nAChRs containing alpha3 and alpha6 subunits. PMID:15044624

McIntosh, J Michael; Azam, Layla; Staheli, Sarah; Dowell, Cheryl; Lindstrom, Jon M; Kuryatov, Alexander; Garrett, James E; Marks, Michael J; Whiteaker, Paul

2004-04-01

123

Time-dependent theory of alpha decay  

Microsoft Academic Search

Using Green's function techniques a time-dependent theory of ..cap alpha.. decay in the standard one-body model is developed. Formulas are obtained for the decay rate and ..cap alpha.. energy. These formulas are combined with experimental information to show that to a good approximation the initial ..cap alpha..-particle wave function vanishes on or near the nuclear surface.

Michael G. Fuda

1984-01-01

124

Time-dependent theory of alpha decay  

SciTech Connect

Using Green's function techniques a time-dependent theory of ..cap alpha.. decay in the standard one-body model is developed. Formulas are obtained for the decay rate and ..cap alpha.. energy. These formulas are combined with experimental information to show that to a good approximation the initial ..cap alpha..-particle wave function vanishes on or near the nuclear surface.

Fuda, M.G.

1984-09-01

125

Alpha particle condensation and nuclear rainbow scattering  

E-print Network

It is shown that a dilute property of an $\\alpha$ particle condensate can be seen in the Airy structure of nuclear rainbow and prerainbow scattering. The dilute property of the Hoyle state of $^{12}$C with a developed $\\alpha$ cluster structure is discussed by studying refractive $^3$He+$^{12}$C and $\\alpha$+$^{12}$C scattering.

S Ohkubo; Y Hirabayashi

2011-02-09

126

Recent Results on the CKM Angle Alpha  

SciTech Connect

The method to measure the CKM angle {alpha} and the modes sensitive to it are discussed. It is shown that the B {yields} {rho}{rho} decays provide the most stringent constraint on {alpha}, which is found to be {alpha} = 96{sup o} {+-} 10{sup o}(stat) {+-} 4{sup o}(syst){+-} 13{sup o}(penguin).

Mihalyi, A.; /Wisconsin U., Madison

2005-10-18

127

Atypical Alpha Asymmetry in Adults with ADHD  

ERIC Educational Resources Information Center

Introduction: A growing body of literature suggests atypical cerebral asymmetry and interhemispheric interaction in ADHD. A common means of assessing lateralized brain function in clinical populations has been to examine the relative proportion of EEG alpha activity (8-12 Hz) in each hemisphere (i.e., alpha asymmetry). Increased rightward alpha…

Hale, T. Sigi; Smalley, Susan L.; Hanada, Grant; Macion, James; McCracken, James T.; McGough, James J.; Loo, Sandra K.

2009-01-01

128

Ageismus – Sprachliche Diskriminierung des Alters  

Microsoft Academic Search

Daniel Sanders, einer der bedeutendsten Lexikografen des 19. Jahrhunderts, wertete für sein Wörterbuch Quellen seit der Lutherzeit aus und\\u000a vermerkt im Wörterbuchartikel zu alt eine „bald lobende, bald tadelnde“ Bedeutung des Adjektivs. Sein Zeit- und Berufsgenosse Jacob Grimm benennt in seiner Rede über das Alter die zeitgenössischen Synonyme zu alt und Alter: „aus einheimischen schriftstellern liesze sich eine lange reihe

Undine Kramer

129

Refinement of the $n-\\alpha$ and $p-\\alpha$ fish-bone potential  

E-print Network

The fishbone potential of composite particles simulates the Pauli effect by nonlocal terms. We determine the $n-\\alpha$ and $p-\\alpha$ fish-bone potential by simultaneously fitting to the experimental phase shifts. We found that with a double Gaussian parametrization of the local potential can describe the $n-\\alpha$ and $p-\\alpha$ phase shifts for all partial waves.

Smith, E; Papp, Z

2012-01-01

130

Efficient synthesis of serically constrained smmetrically alpha,alpha-disubstituted alpha-amino acids under operationally convenient conditions.  

PubMed

Homologation of the nucleophilic glycine equivalent Ni-Gly-PABP [Ni(II) complex of glycine Schiff base with 2-[N-(alpha-picolyl)amino]benzophenone (PABP)] 2 via alkyl halide alkylations and Michael addition reactions was systematically studied as a general method for preparing symmetrically alpha,alpha-disubstituted alpha-amino acids (sym-alpha,alpha-AA). The dialkylation reactions are conducted under operationally convenient conditions without recourse to inert atmosphere, dried solvents, and low temperatures, thus enjoying key advantages of the experimental simplicity and attractive cost structure. The method has been shown to be particularly successful for the dialkylation of complex 2 with activated and nonactivated alkyl halides, including propargyl derivatives, affording a generalized and practical access to the corresponding sym-alpha,alpha-AA. This study has also shown some limitation of the method, as it cannot be extended to alpha- or beta-branched alkyl halides or Michael acceptors to be used for the dialkylation of glycine equivalent 2. High chemical yields of the dialkylated products, combined with the simplicity of the experimental procedure, render this method worth immediate use for multigram scale preparation of the sym-alpha,alpha-AA. PMID:12895052

Ellis, Trevor K; Martin, Collin H; Tsai, Gary M; Ueki, Hisanori; Soloshonok, Vadim A

2003-08-01

131

The Alpha 21264 microprocessor architecture  

Microsoft Academic Search

The 21264 is the third generation Alpha microprocessor from Compaq Computer (formerly Digital Equipment) Corporation. This microprocessor achieves the industry-leading performance levels of 30+ Specint95 and 50+ Specfp95. In addition to the aggressive 600 MHz cycle time in a 0.35 ?m CMOS process, there are also many architectural features that enable the outstanding performance level of the 21264. This paper

R. E. Kessler; E. J. McLellan; D. A. Webb

1998-01-01

132

Des Moines Water Works  

NSDL National Science Digital Library

Users can access information about educational programs and materials for teachers and students, including tours, traveling exhibits and presentations by the staff of the Des Moines Water Works. "Water Trunks", which contain water-related literature, books, science experiments, videos, games, CD-ROMs, hands-on activities, picture cards, career information, and a teacher resource book, are available to order. There are also links to other water websites, a teachers' newsletter and pollution prevention tips for classroom use and for the general public.

2001-01-01

133

Possible bioactive conformations of alpha-melanotropin.  

PubMed

By comparing the results of energy calculation for alpha-MSH and its semirigid analogues Ac-[ Cys4 , Cys10 ]-alpha- MSH4 -10-NH2, Ac-[ Cys4 , Cys10 ]-alpha- MSH4 -13-NH2, and [ Cys4 - Cys10 ]-alpha-MSH, a detailed description of two possible bioactive conformations for the 'specific' central site of alpha- MSH6 -9 is proposed representing variants of chain-reversal structure. A possible explanation of the rise in melanotropic activity of the latter two semirigid analogues is presented. PMID:6723968

Nikiforovich, G V; Rozenblit, S A; Shenderovich, M D; Chipens, G I

1984-05-21

134

Alpha voltaic batteries and methods thereof  

NASA Technical Reports Server (NTRS)

An alpha voltaic battery includes at least one layer of a semiconductor material comprising at least one p/n junction, at least one absorption and conversion layer on the at least one layer of semiconductor layer, and at least one alpha particle emitter. The absorption and conversion layer prevents at least a portion of alpha particles from the alpha particle emitter from damaging the p/n junction in the layer of semiconductor material. The absorption and conversion layer also converts at least a portion of energy from the alpha particles into electron-hole pairs for collection by the one p/n junction in the layer of semiconductor material.

Raffaelle, Ryne P. (Inventor); Jenkins, Phillip (Inventor); Wilt, David (Inventor); Scheiman, David (Inventor); Chubb, Donald (Inventor); Castro, Stephanie (Inventor)

2011-01-01

135

THE LYMAN ALPHA REFERENCE SAMPLE: EXTENDED LYMAN ALPHA HALOS PRODUCED AT LOW DUST CONTENT  

SciTech Connect

We report on new imaging observations of the Lyman alpha emission line (Ly{alpha}), performed with the Hubble Space Telescope, that comprise the backbone of the Lyman alpha Reference Sample. We present images of 14 starburst galaxies at redshifts 0.028 < z < 0.18 in continuum-subtracted Ly{alpha}, H{alpha}, and the far ultraviolet continuum. We show that Ly{alpha} is emitted on scales that systematically exceed those of the massive stellar population and recombination nebulae: as measured by the Petrosian 20% radius, R{sub P20}, Ly{alpha} radii are larger than those of H{alpha} by factors ranging from 1 to 3.6, with an average of 2.4. The average ratio of Ly{alpha}-to-FUV radii is 2.9. This suggests that much of the Ly{alpha} light is pushed to large radii by resonance scattering. Defining the Relative Petrosian Extension of Ly{alpha} compared to H{alpha}, {xi}{sub Ly{alpha}} = R {sup Ly{alpha}}{sub P20}/R {sup H{alpha}}{sub P20}, we find {xi}{sub Ly{alpha}} to be uncorrelated with total Ly{alpha} luminosity. However, {xi}{sub Ly{alpha}} is strongly correlated with quantities that scale with dust content, in the sense that a low dust abundance is a necessary requirement (although not the only one) in order to spread Ly{alpha} photons throughout the interstellar medium and drive a large extended Ly{alpha} halo.

Hayes, Matthew [Universite de Toulouse, UPS-OMP, IRAP, Toulouse (France); Oestlin, Goeran; Duval, Florent; Guaita, Lucia; Melinder, Jens; Sandberg, Andreas [Department of Astronomy, Oskar Klein Centre, Stockholm University, AlbaNova University Centre, SE-106 91 Stockholm (Sweden); Schaerer, Daniel [CNRS, IRAP, 14, avenue Edouard Belin, F-31400 Toulouse (France); Verhamme, Anne; Orlitova, Ivana [Geneva Observatory, University of Geneva, 51 Chemin des Maillettes, CH-1290 Versoix (Switzerland); Mas-Hesse, J. Miguel; Oti-Floranes, Hector [Centro de Astrobiologia (CSIC-INTA), Departamento de Astrofisica, POB 78, 28691 Villanueva de la Canada (Spain); Adamo, Angela [Max Planck Institute for Astronomy, Koenigstuhl 17, D-69117 Heidelberg (Germany); Atek, Hakim [Laboratoire d'Astrophysique, Ecole Polytechnique Federale de Lausanne (EPFL), Observatoire, CH-1290 Sauverny (Switzerland); Cannon, John M. [Department of Physics and Astronomy, Macalester College, 1600 Grand Avenue, Saint Paul, MN 55105 (United States); Herenz, E. Christian [Leibniz-Institut fuer Astrophysik (AIP), An der Sternwarte 16, D-14482 Potsdam (Germany); Kunth, Daniel [Institut d'Astrophysique de Paris, UMR 7095 CNRS and UPMC, 98 bis Bd Arago, F-75014 Paris (France); Laursen, Peter, E-mail: matthew@astro.su.se [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen (Denmark)

2013-03-10

136

Gntique formelle des pigmentations humaines variations continues  

E-print Network

Génétique formelle des pigmentations humaines à variations continues : beaucoup d'hypothèses, peu et de mesures sont actuellement disponibles concer- nant la biochimie des pigments humains, leur génétique physiologique, les répartitions mondiales des pigmentations de la peau et des cheveux. La

Boyer, Edmond

137

Les revenus primaires des ménages en 1975  

Microsoft Academic Search

[fre] Tous les 5 ans environ, l'INSEE procède à une enquête sur les revenus des ménages en utilisant les déclarations fiscales de la Direction générale des impôts. Les premiers résultats de 1975 sont à présent disponibles. Malgré la diversité des critères d'inégalité (revenu par ménage, par tête ou par unité de consommation), une réduction progressive des écarts se fait jour,

André Villeneuve

1978-01-01

138

Patrimoine des ménages : déterminants et disparités  

Microsoft Academic Search

[fre] Patrimoine des ménages : déterminants et disparités . En 1992, le patrimoine brut des ménages est, en moyenne, de 900 000 francs. Mais la dispersion et la concentration sont fortes : le pécule des 10 % de ménages les moins fortunés ne dépasse pas 24 600 francs, alors que l'avoir des 10 % les plus riches excède 1 830

Daniel Verger; Stéfan Lollivier

1996-01-01

139

CARTOGRAPHIE DES ACCIDENTS GOLOGIQUES PAR IMAGERIE  

E-print Network

119 CARTOGRAPHIE DES ACCIDENTS G�OLOGIQUES PAR IMAGERIE SATELLITAIRE LANDSAT-7 ETM+ ET ANALYSE DES cartographier les réseaux de fractures dans les roches cristallines et métamorphiques à l'aide des images les images brutes, permettant une meilleure cartographie des accidents géologiques. La carte

Paris-Sud XI, Université de

140

DTERMINATION QUANTITATIVE DES DENSITS LEVES DES DISLOCATIONS DANS DES MONOCRISTAUX DE GERMANIUM  

E-print Network

GERMANIUM PAR DIFFUSION D'ATOMES MARQU�S Par MAREK BRAFMAN, OLGA KRUSZEWSKA, WALDEMAR WRONSKI et KAROL'exemple des monocristaux de germanium et comparaison des résultats obtenus avec les mêmes déterminations measurement of the density of the autoradio- grams. The method is illustrated by example of germanium

Boyer, Edmond

141

Sécurité au-delà des mythes et des croyances  

ScienceCinema

Présentation orale en français, support visuel en français et en anglais. La pire des failles de sécurité est l'impression de sécurité. Le décalage entre la compréhension que l?on a des technologies utilisées, et leurs potentiels réels, ainsi que l'impact potentiellement négatif qu'elles peuvent avoir sur nos vies, n'est pas toujours compris, ou pris en compte par la plupart d'entre-nous. On se contente de nos perceptions pour ne pas avoir à se confronter à la réalité... Alors qu'en est-il vraiment ? En matière de sécurité qui de l'humain ou des technologies a le contrôle ?

None

2011-10-06

142

A propos des divergences en théorie des champs quantifiés [83  

NASA Astrophysics Data System (ADS)

Comme nous le montrons ailleurs1), la causalité impose à la matrice S qui décrit l'évolution d'un système une structure bien déterminée : lorsqu'on développe celle-ci suivant les opérateurs de translation dans l'espace des quanta, les coefficients S^{(i)} left[ {tau ''; u''../tau '; u' \\cdot \\cdot } right] sont des intégrales multiples où n'apparaissent, à cOté des champs liés à un seul point de l'espace temps, que les functions*): D^c (x/y) = D^s (x/y) + _2^i D^1 (x/y) x ne y

143

Pacs des villes et pas des champs ? Emmanuel Jaurand  

E-print Network

). Après le pic de 2000, le total annuel de signatures de pacs entre personnes du même sexe a oscillé entre désormais être affinée en fonction du sexe des pacsés. La répartition des pacs entre personnes du même sexe'organiser juridiquement une vie de couple quel que soit le sexe des partenaires, le pacs a d'abord été une innovation

Paris-Sud XI, Université de

144

Insulin-like growth factor-1 downregulates nuclear factor kappa B activation and upregulates interleukin-8 gene expression induced by tumor necrosis factor alpha.  

PubMed

Pretreatment of HT29-D4 epithelial adenocarcinoma colic cells with des-IGF-1 upregulated TNF alpha-mediated activation of IL-8 expression at different levels (protein, mRNA, and hnRNA). RNA transcription but not RNA stabilization was found to be involved. In this cell line, cooperation of NF-kappa B with other factors appeared essential for IL-8 expression. Indeed, TNF alpha-induced NF-kappa B translocation was not sufficient to support enhancement of the transcription and des-IGF-1 did not promote but partly inhibited both the TNF alpha-induced NF-kappa B activation and I kappa B alpha degradation through a PI-3K-dependent pathway. A CCAAT/enhancer binding protein (C/EBP) site located on the IL-8 gene enhancer cooperated with a NF-kappa B binding site and led to the upregulation of IL-8 expression. Binding of C/EBP alpha to this sequence disappeared in IGF-1 treated cells. This event may be important for the cross-talk between IGF-1- and TNF alpha-mediated pathways leading to the control of inflammatory processes and the decision concerning apoptosis or cell survival. PMID:12767906

Vallée, Sébastien; Fouchier, Francis; Brémond, Patricia; Briand, Claudette; Marvaldi, Jacques; Champion, Serge

2003-06-13

145

Die Rolle des Publikums fokussiert auf die Optionen der Mitgestaltung im öffentlich-rechtlichen Fernsehangebot des ORF in Österreich.  

E-print Network

??Untersuchungsgegenstand: Im Zentrum steht die Option und Ausführung des „Mitspracherechts“ des Publikums an fernsehpublizistischen Inhalten des öffentlich-rechtlichen Rundfunks ORF in Österreich, sowie das Angebot der… (more)

Scherzinger, Ronja-Svenja

2012-01-01

146

Recoil-alpha-fission and recoil-alpha-alpha-fission events observed in the reaction Ca-48 + Am-243  

E-print Network

Products of the fusion-evaporation reaction Ca-48 + Am-243 were studied with the TASISpec set-up at the gas-filled separator TASCA at the GSI Helmholtzzentrum f\\"ur Schwerionenforschung. Amongst the detected thirty correlated alpha-decay chains associated with the production of element Z=115, two recoil-alpha-fission and five recoil-alpha-alpha-fission events were observed. The latter are similar to four such events reported from experiments performed at the Dubna gas-filled separator. Contrary to their interpretation, we propose an alternative view, namely to assign eight of these eleven decay chains of recoil-alpha(-alpha)-fission type to start from the 3n-evaporation channel 115-288. The other three decay chains remain viable candidates for the 2n-evaporation channel 115-289.

Forsberg, U; Andersson, L -L; Di Nitto, A; Düllmann, Ch E; Gates, J M; Golubev, P; Gregorich, K E; Gross, C J; Herzberg, R -D; Hessberger, F P; Khuyagbaatar, J; Kratz, J V; Rykaczewski, K; Sarmiento, L G; Schädel, M; Yakushev, A; Åberg, S; Ackermann, D; Block, M; Brand, H; Carlsson, B G; Cox, D; Derkx, X; Dobaczewski, J; Eberhardt, K; Even, J; Fahlander, C; Gerl, J; Jäger, E; Kindler, B; Krier, J; Kojouharov, I; Kurz, N; Lommel, B; Mistry, A; Mokry, C; Nazarewicz, W; Nitsche, H; Omtvedt, J P; Papadakis, P; Ragnarsson, I; Runke, J; Schaffner, H; Schausten, B; Shi, Y; Thörle-Pospiech, P; Torres, T; Traut, T; Trautmann, N; Türler, A; Ward, A; Ward, D E; Wiehl, N

2015-01-01

147

Recoil-alpha-fission and recoil-alpha-alpha-fission events observed in the reaction Ca-48 + Am-243  

E-print Network

Products of the fusion-evaporation reaction Ca-48 + Am-243 were studied with the TASISpec set-up at the gas-filled separator TASCA at the GSI Helmholtzzentrum f\\"ur Schwerionenforschung. Amongst the detected thirty correlated alpha-decay chains associated with the production of element Z=115, two recoil-alpha-fission and five recoil-alpha-alpha-fission events were observed. The latter are similar to four such events reported from experiments performed at the Dubna gas-filled separator. Contrary to their interpretation, we propose an alternative view, namely to assign eight of these eleven decay chains of recoil-alpha(-alpha)-fission type to start from the 3n-evaporation channel 115-288. The other three decay chains remain viable candidates for the 2n-evaporation channel 115-289.

U. Forsberg; D. Rudolph; L. -L. Andersson; A. Di Nitto; Ch. E. Düllmann; J. M. Gates; P. Golubev; K. E. Gregorich; C. J. Gross; R. -D. Herzberg; F. P. Hessberger; J. Khuyagbaatar; J. V. Kratz; K. Rykaczewski; L. G. Sarmiento; M. Schädel; A. Yakushev; S. Åberg; D. Ackermann; M. Block; H. Brand; B. G. Carlsson; D. Cox; X. Derkx; J. Dobaczewski; K. Eberhardt; J. Even; C. Fahlander; J. Gerl; E. Jäger; B. Kindler; J. Krier; I. Kojouharov; N. Kurz; B. Lommel; A. Mistry; C. Mokry; W. Nazarewicz; H. Nitsche; J. P. Omtvedt; P. Papadakis; I. Ragnarsson; J. Runke; H. Schaffner; B. Schausten; Y. Shi; P. Thörle-Pospiech; T. Torres; T. Traut; N. Trautmann; A. Türler; A. Ward; D. E. Ward; N. Wiehl

2015-02-10

148

Plan de cours Facult des arts et des sciences  

E-print Network

types d'organisation des monères, protistes, mycètes, algues et plantes. #12;SYLLABUS G�N�RAL Date Cours et de systématique. 16 septembre 2 Origine et évolution des Eucaryotes. Straménopiles (Algues Brunes (lichens et mycorhizes) et Myxomycètes. 7 octobre 5 Algues de la Lignée Verte (Glaucophytes, Rhodophytes

Parrott, Lael

149

Plan de cours Facult des arts et des sciences  

E-print Network

des êtres vivants ; · structures et types d'organisation des monères, protistes, mycètes, algues et. Straménopiles (Algues Brunes, Diatomées et Oomycètes). 22 septembre 3 Protozoaires. 29 septembre 4 Mycètes, Associations fongiques (lichens et mycorhizes) et Myxomycètes. 6 octobre 5 Algues de la Lignée Verte

Parrott, Lael

150

UNIVERSIT DE NANTES FACULT DES SCIENCES ET DES TECHNIQUES  

E-print Network

'ophiolite d'Oman et au programme d'étude des nouvelles AOC des Muscadet de la région nantaise ______ TH�SE DE............................................................. 51 2.2 Contexte géologique de l'ophiolite d'Oman ..................................................................................................................................... 54 2.2.2 Formation de l'ophiolite et unités lithologiques affleurant dans les montagnes d'Oman

Paris-Sud XI, Université de

151

High gas flow alpha detector  

DOEpatents

An alpha detector for application in areas of high velocity gas flows, such as smokestacks and air vents. A plurality of spaced apart signal collectors are placed inside an enclosure, which would include smokestacks and air vents, in sufficient numbers to substantially span said enclosure so that gas ions generated within the gas flow are electrostatically captured by the signal collector means. Electrometer means and a voltage source are connected to the signal collectors to generate an electrical field between adjacent signal collectors, and to indicate a current produced through collection of the gas ions by the signal collectors. 4 figs.

Bolton, R.D.; Bounds, J.A.; Rawool-Sullivan, M.W.

1996-05-07

152

High gas flow alpha detector  

DOEpatents

An alpha detector for application in areas of high velocity gas flows, such as smokestacks and air vents. A plurality of spaced apart signal collectors are placed inside an enclosure, which would include smokestacks and air vents, in sufficient numbers to substantially span said enclosure so that gas ions generated within the gas flow are electrostatically captured by the signal collector means. Electrometer means and a voltage source are connected to the signal collectors to generate an electrical field between adjacent signal collectors, and to indicate a current produced through collection of the gas ions by the signal collectors.

Bolton, Richard D. (Los Alamos, NM); Bounds, John A. (Los Alamos, NM); Rawool-Sullivan, Mohini W. (Los Alamos, NM)

1996-01-01

153

Targeted alpha therapy for cancer  

NASA Astrophysics Data System (ADS)

Targeted alpha therapy (TAT) offers the potential to inhibit the growth of micrometastases by selectively killing isolated and preangiogenic clusters of cancer cells. The practicality and efficacy of TAT is tested by in vitro and in vivo studies in melanoma, leukaemia, colorectal, breast and prostate cancers, and by a phase 1 trial of intralesional TAT for melanoma. The alpha-emitting radioisotope used is Bi-213, which is eluted from the Ac-225 generator and chelated to a cancer specific monoclonal antibody (mab) or protein (e.g. plasminogen activator inhibitor-2 PAI2) to form the alpha-conjugate (AC). Stable alpha-ACs have been produced which have been tested for specificity and cytotoxicity in vitro against melanoma (9.2.27 mab), leukaemia (WM60), colorectal (C30.6), breast (PAI2, herceptin), ovarian (PAI2, herceptin, C595), prostate (PAI2, J591) and pancreatic (PAI2, C595) cancers. Subcutaneous inoculation of 1-1.5 million human cancer cells into the flanks of nude mice causes tumours to grow in all mice. Tumour growth is compared for untreated controls, nonspecific AC and specific AC, for local (subcutaneous) and systemic (tail vein or intraperitoneal) injection models. The 213Bi-9.2.27 AC is injected into secondary skin melanomas in stage 4 patients in a dose escalation study to determine the effective tolerance dose, and to measure kinematics to obtain the equivalent dose to organs. In vitro studies show that TAT is one to two orders of magnitude more cytotoxic to targeted cells than non-specific ACs, specific beta emitting conjugates or free isotopes. In vivo local TAT at 2 days post-inoculation completely prevents tumour formation for all cancers tested so far. Intra-lesional TAT can completely regress advanced sc melanoma but is less successful for breast and prostate cancers. Systemic TAT inhibits the growth of sc melanoma xenografts and gives almost complete control of breast and prostate cancer tumour growth. Intralesional doses up to 450 µCi in human patients are effective in regressing melanomas, with no concomitant complications. These results point to the application of local and systemic TAT in the management of secondary cancer. Results of the phase 1 clinical trial of TAT of subcutaneous, secondary melanoma indicate proof of the principle that TAT can make tumours in patients regress.

Allen, Barry J.; Raja, Chand; Rizvi, Syed; Li, Yong; Tsui, Wendy; Zhang, David; Song, Emma; Qu, Chang Fa; Kearsley, John; Graham, Peter; Thompson, John

2004-08-01

154

Concomitant dehydration mechanisms in single crystals of alpha,alpha-trehalose.  

PubMed

The dehydration behaviour of alpha,alpha-trehalose (alpha-D-glucopyranosyl alpha-D-glucopyranoside) dihydrate single crystals is investigated by thermomicroscopy, Raman microscopy, and differential scanning calorimetry. The results show at a given stage the simultaneous presence of two polymorphic forms, amorphous material, and movement of a fluid phase. The study also underlines that the characterization of the average phase by conventional XRPD and DSC techniques is not sufficient to describe the dehydration mechanisms of alpha,alpha-trehalose particles. Moreover, it confirms that the dehydration behaviour is mainly driven by heterogeneities and the rate of water loss. PMID:19875105

Dupray, Valérie; Berton, Benjamin; Ossart, Stephen; Atmani, Hassan; Petit, Marie-Noëlle; Coquerel, Gérard

2009-12-14

155

Musee des Horreurs  

NSDL National Science Digital Library

What is this Musee des Horreurs? Visitors will find out soon enough: it is a remarkable collection of 52 hand-colored lithograph caricatures of individuals involved in the Dreyfus Affair in France. These lithographs were originally produced from 1899 to 1900 by an artist who used the pseudonym V. Lenepveu and they document the anti-Semitic upsurge brought about by this well-known event. Those represented in the caricatures include prominent members of the Jewish community, Dreyfus supporters, and Republican statesmen placed on grotesque animal bodies. Visitors with an interest in the subject may wish to use the images in a class on graphic design, illustration, European history, or cultural affairs.

156

Die fermentative Spaltung des Acetylcholins  

Microsoft Academic Search

Zusammenfassung Es wird eine neue Methode zum Nachweis des Fermentes, das Acetylcholin in Cholin und Essigsäure hydrolysiert, die Cholinesterase, beschrieben. Das Verfahren ist nach derWarburgschen Methode aufgebaut.

R. Ammon

1934-01-01

157

{alpha} decay of {sup 105}Te  

SciTech Connect

The {alpha} decay of the neutron-deficient nuclide {sup 105}Te was observed. The {sup 50}Cr({sup 58}Ni,3n) reaction was used to produce {sup 105}Te nuclei. The {sup 105}Te residues were selected with the Argonne Fragment Mass Analyzer and implanted into a double-sided Si strip detector where their subsequent {alpha} decay was detected. An {alpha}-decay Q value of Q{sub {alpha}}=4900(50) keV and a half life of T{sub 1/2}=0.70(-0.17+0.25){mu}s were measured for {sup 105}Te and a reduced {alpha}-decay width of W{sub {alpha}}=3.3(-1.7+2.1) was deduced. The decay properties of {sup 105}Te are compared with those of heavier Te isotopes and theoretical predictions.

Seweryniak, D.; Davids, C.N.; Gros, S.; Khoo, T.L.; Peterson, D.; Robinson, A.; Zhu, S. [Argonne National Laboratory, Argonne, Illinois 60439 (United States); Starosta, K.; Vaman, C. [National Superconducting Cyclotron Laboratory, East Lansing, Michigan 48824 (United States); Hecht, A.A.; Hoteling, N.; Walters, W.B. [University of Maryland, College Park, Maryland 20742 (United States); Lagergren, K.; Woods, P.J. [Department of Physics, Florida State University, Tallahassee, Florida 32306 (United States); Lotay, G. [University of Edinburgh, Edinburgh EH9 3JZ (United Kingdom)

2006-06-15

158

Alpha Subunit Position and GABA Receptor Function  

NSDL National Science Digital Library

GABAA (γ-aminobutyric acid type A) receptors are ligand-gated ion channels composed of five subunits, generally two &alpha;s, two βs, and a γ2. Recent research in which sets of subunits containing &alpha;1 or &alpha;6 subunits were artificially linked has revealed the importance of subunit position in determining GABAA receptor function. Sensitivity to benzodiazepines depended on juxtaposition of an &alpha;1 subunit with the γ2 subunit, whereas sensitivity to furosemide depended only on the presence of an &alpha;6 subunit and not on its specific location. The major utility of the linked subunit approach is to provide a mechanism for discovering the functional signatures of defined subunit arrangements, and thus a route to identifying such arrangements in vivo.

David R. Burt (University of Maryland School of Medicine;Department of Pharmacology REV)

2005-02-08

159

Local Varying-Alpha Theories  

E-print Network

In a recent paper we demonstrated how the simplest model for varying alpha may be interpreted as the effect of a dielectric material, generalized to be consistent with Lorentz invariance. Unlike normal dielectrics, such a medium cannot change the speed of light, and its dynamics obey a Klein-Gordon equation. This work immediately suggests an extension of the standard theory, even if we require compliance with Lorentz invariance. Instead of a wave equation, the dynamics may satisfy a local algebraic relation involving the permittivity and the properties of the electromagnetic field, in analogy with more conventional dielectric (but still preserving Lorentz invariance). We develop the formalism for such theories and investigate some phenomenological implications. The problem of the divergence of the classical self-energy can be solved, or at least softened, in this framework. Some interesting new cosmological solutions for the very early universe are found, including the possibility of a bounce, inflation and expansion with a loitering phase, all of which are induced by early variations in alpha.

John D. Barrow; Joao Magueijo

2015-01-30

160

Thorie des ensembles 1. Motivation  

E-print Network

, comme Georg Cantor (1845-1918), Giuseppe Peano (1858-1932), Bertrand Russell (1872-1970) et autres. Nous de la démonstration (2). Figure I.1. Georg Cantor, Giuseppe Peano et Bertrand Russell La plupart des chasser du paradis que Cantor nous a bâti» (1). Plus tard, en parlant au Congrès des Mathématiciens à

Dolecki, Szymon

161

Beta/alpha continuous air monitor  

DOEpatents

A single deep layer silicon detector in combination with a microcomputer, recording both alpha and beta activity and the energy of each pulse, distinguishing energy peaks using a novel curve fitting technique to reduce the natural alpha counts in the energy region where plutonium and other transuranic alpha emitters are present, and using a novel algorithm to strip out radon daughter contribution to actual beta counts.

Becker, Gregory K. (Idaho Falls, ID); Martz, Dowell E. (Grand Junction, CO)

1989-01-01

162

Beta/alpha continuous air monitor  

DOEpatents

A single deep layer silicon detector in combination with a microcomputer, recording both alpha and beta activity and the energy of each pulse, distinquishing energy peaks using a novel curve fitting technique to reduce the natural alpha counts in the energy region where plutonium and other transuranic alpha emitters are present, and using a novel algorithm to strip out radon daughter contribution to actual beta counts. 7 figs.

Becker, G.K.; Martz, D.E.

1988-06-27

163

On strongly [alpha]-preinvex functions  

NASA Astrophysics Data System (ADS)

In this paper, by means of a series of counterexamples, we study in a systematic way the relationships among (pseudo, quasi) [alpha]-preinvexity, (strict, strong, pseudo, quasi) [alpha]-invexity and (strict, strong, pseudo, quasi) [alpha][eta]-monotonicity. Results obtained in this paper can be viewed as a refinement and improvement of the results of Noor and Noor [M.A. Noor, K.I. Noor, Some characterizations of strongly preinvex functions, J. Math. Anal. Appl. 316 (2006) 697-706].

Fan, Liya; Guo, Yunlian

2007-06-01

164

/sup 20/Ne(. cap alpha. ,2. cap alpha. )/sup 16/O reaction  

SciTech Connect

The /sup 20/Ne(..cap alpha..,2..cap alpha..)/sup 16/O reaction at 140 MeV incident energy is analyzed in the framework of the distorted-wave impulse approximation. The bound state ..cap alpha.. wave functions in /sup 20/Ne are generated using the orthogonal condition model. The predicted results agree with the experimental data. They are also in rough accord with the results obtained with the Woods-Saxon ..cap alpha.. wave function.

Sharma, N.R.; Jain, B.K.; Shyam, R.

1988-02-01

165

The first transformation of aliphatic alpha,beta-epoxyamides into alpha-hydroxyamides.  

PubMed

A general synthesis of aliphatic alpha-hydroxyamides with total regioselectivity by a reductive cleaveage of the C(beta)-O bond of aliphatic alpha,beta-epoxyamides, promoted by samarium diiodide and MeOH, is described. The treatment of enantiopure aliphatic alpha,beta-epoxyamides afforded enantiomerically enriched aliphatic alpha-hydroxyamides. A radical mechanism has been proposed to explain this reaction. [reaction: see text] PMID:14653673

Concellón, José M; Bardales, Eva

2003-12-11

166

Stereoselective desymmetrisation of prochiral alpha,alpha-dicyanoalkenes via domino Michael-Michael addition reactions.  

PubMed

The desymmetrisation of prochiral alpha,alpha-dicyanoalkenes via tandem Michael-Michael addition reactions with alpha,beta-unsaturated ketones catalysed by 9-amino-9-deoxyepicinchona alkaloids was investigated, from which bicyclic products bearing four stereogenic centers were afforded in a single operation with high stereoselectivities (>99% de, up to >99.5% ee). PMID:18633522

Kang, Tai-Ran; Xie, Jian-Wu; Du, Wei; Feng, Xin; Chen, Ying-Chun

2008-08-01

167

Alpha-conotoxin PIA is selective for alpha6 subunit-containing nicotinic acetylcholine receptors.  

PubMed

Until now, there have been no antagonists to discriminate between heteromeric nicotinic acetylcholine receptors (nAChRs) containing the very closely related alpha6 and alpha3 subunits. nAChRs containing alpha3, alpha4, or alpha6 subunits in combination with beta2, occasionally beta4, and sometimes beta3 or alpha5 subunits, are thought to play important roles in cognitive function, pain perception, and the reinforcing properties of nicotine. We cloned a novel gene from the predatory marine snail Conus purpurascens. The predicted peptide, alpha-conotoxin PIA, potently blocks the chimeric alpha6/alpha3beta2beta3 subunit combination as expressed in oocytes but neither the muscle nor the major neuronal nAChR alpha4beta2. Additionally, this toxin is the first described ligand to discriminate between nAChRs containing alpha6 and alpha3 subunits. Exploiting the unusual intron conservation of conotoxin genes may represent a more general approach for defining conotoxin ligand scaffolds to discriminate among closely related receptor populations. PMID:13679412

Dowell, Cheryl; Olivera, Baldomero M; Garrett, James E; Staheli, Sarah T; Watkins, Maren; Kuryatov, Alexander; Yoshikami, Doju; Lindstrom, Jon M; McIntosh, J Michael

2003-09-17

168

Evidence for an alpha cluster condensed state in 16O(alpha,alpha') at 400 MeV  

E-print Network

Inelastic $\\alpha$ scattering on 16O is studied at 400 MeV by using an ice target. Near the 4-alpha breakup threshold of 14.4 MeV, a broad peak is observed at an excitation energy of 13.6+/-0.2 MeV with a width of 0.6+/-0.2 MeV. The spin-parity is estimated to be 0+ from the momentum-transfer dependence. The observed width is significantly larger than those of the neighboring 0+ states indicating a state with a well-developed alpha cluster structure. The magnitude of the cross section is sensitive to the density distribution of the constituent alpha clusters. The observed cross section is consistent with the theoretical prediction for the alpha cluster condensed state characterized by its dilute density distribution with a large root-mean-square radius of about 4.3 fm.

T. Wakasa; E. Ihara; K. Fujita; Y. Funaki; K. Hatanaka; H. Horiuchi; M. Itoh; J. Kamiya; G. Ropke; H. Sakaguchi; N. Sakamoto; Y. Sakemi; P. Schuck; Y. Shimizu; M. Takashina; S. Terashima; A. Tohsaki; M. Uchida; H. P. Yoshida; M. Yosoi

2006-11-13

169

Local Varying-Alpha Theories  

E-print Network

In a recent paper we demonstrated how the simplest model for varying alpha may be interpreted as the effect of a dielectric material, generalized to be consistent with Lorentz invariance. Unlike normal dielectrics, such a medium cannot change the speed of light, and its dynamics obey a Klein-Gordon equation. This work immediately suggests an extension of the standard theory, even if we require compliance with Lorentz invariance. Instead of a wave equation, the dynamics may satisfy a local algebraic relation involving the permittivity and the properties of the electromagnetic field, in analogy with more conventional dielectric (but still preserving Lorentz invariance). We develop the formalism for such theories and investigate some phenomenological implications. The problem of the divergence of the classical self-energy can be solved, or at least softened, in this framework. Some interesting new cosmological solutions for the very early universe are found, including the possibility of a bounce, inflation and e...

Barrow, John D

2014-01-01

170

Les limites de la couverture des risques en aquaculture : le cas des  

E-print Network

EA 4272 Les limites de la couverture des risques en aquaculture : le cas des conchyliculteurs en limites de la couverture des risques en aquaculture : le cas des conchyliculteurs en France Véronique Le in defining risks in aquaculture and we propose a classification that takes the specificities into account. We

Paris-Sud XI, Université de

171

Le got des ignames de Madagascar 1 valuation sensorielle de la perception des ignames de Madagascar,  

E-print Network

Le goût des ignames de Madagascar 1 �valuation sensorielle de la perception des ignames de Madagascar, dans le contexte des connaissances actuelles en psychophysiologie de la gustation par Claude endémiques de Madagascar, nous avons entrepris des tests d'évaluation sensorielle qui nous sont apparus comme

Paris-Sud XI, Université de

172

L'évolution des rythmes de travail entre 1995 et 2001 : quel impact des 35 heures ?  

Microsoft Academic Search

[fre] L’évolution des rythmes de travail entre 1995 et 2001: quel impact des 35 heures? . . Le «passage aux 35 heures» ne s’est pas limité à la baisse de la durée légale du travail. La négociation au sein des branches ou des entreprises a, en effet, porté simultanément sur la durée du travail, son organisation, les conditions de travail

Cédric Afsa; Pierre Biscourp

2004-01-01

173

Composition en acides amins des aliments et des rsidus de fermentation in vitro  

E-print Network

Composition en acides aminés des aliments et des résidus de fermentation in vitro M. ANTONGIOVANNI in vitro fermentation with rumen inoculum, and of the faeces relative to an in vivo digestibility trial run fermentation in vitro comme l'ont fait Dennison et Philips (1983) et des fèces. Pour des raisons de place, nous

Paris-Sud XI, Université de

174

Alpha-1 Antitrypsin Deficiency: It's All in the Family  

MedlinePLUS

... It’s All in the Family Whether you have Alpha-1 Antitrypsin Deficiency (Alpha-1) — or are an Alpha-1 “carrier” — we strongly suggest that your relatives ... share with them what you have learned about Alpha-1. How is Alpha-1 inherited? Your genes ...

175

Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist {alpha}-conotoxin OmIA that discriminates {alpha}3 vs. {alpha}6 nAChR subtypes  

SciTech Connect

{alpha}-Conotoxin OmIA from Conus omaria is the only {alpha}-conotoxin that shows a {approx}20-fold higher affinity to the {alpha}3{beta}2 over the {alpha}6{beta}2 subtype of nicotinic acetylcholine receptor. We have determined a three-dimensional structure of {alpha}-conotoxin OmIA by nuclear magnetic resonance spectroscopy. {alpha}-Conotoxin OmIA has an '{omega}-shaped' overall topology with His{sup 5}-Asn{sup 12} forming an {alpha}-helix. Structural features of {alpha}-conotoxin OmIA responsible for its selectivity are suggested by comparing its surface characteristics with other functionally related {alpha}4/7 subfamily conotoxins. Reduced size of the hydrophilic area in {alpha}-conotoxin OmIA seems to be associated with the reduced affinity towards the {alpha}6{beta}2 nAChR subtype.

Chi, Seung-Wook [Molecular Anti-Cancer Research Center, Division of Molecular Therapeutics, Korea Research Institute of Bioscience and Biotechnology, Yusong P.O. Box 115, Daejon (Korea, Republic of); Kim, Do-Hyoung [Molecular Anti-Cancer Research Center, Division of Molecular Therapeutics, Korea Research Institute of Bioscience and Biotechnology, Yusong P.O. Box 115, Daejon (Korea, Republic of); Olivera, Baldomero M. [Department of Biology, University of Utah, Salt Lake City, UT 84112 (United States); McIntosh, J. Michael [Department of Biology, University of Utah, Salt Lake City, UT 84112 (United States); Department of Psychiatry, University of Utah, Salt Lake City, UT 84112 (United States); Han, Kyou-Hoon [Molecular Anti-Cancer Research Center, Division of Molecular Therapeutics, Korea Research Institute of Bioscience and Biotechnology, Yusong P.O. Box 115, Daejon (Korea, Republic of)]. E-mail: khhan600@kribb.re.kr

2006-06-23

176

CAMPAGNE DE RECRUTEMENT DES ENSEIGNANTS-CHERCHEURS -SESSION SYNCHRONISEE 2014 -LISTE des MEMBRES des CDS POSTES DE MAITRES DE CONFERENCE  

E-print Network

Mathématiques, bâtiment Fermat département de Mathématiques et applications Ecole Normale Supérieure InriaCAMPAGNE DE RECRUTEMENT DES ENSEIGNANTS-CHERCHEURS - SESSION SYNCHRONISEE 2014 - LISTE des MEMBRES des CDS POSTES DE MAITRES DE CONFERENCE Numéro Poste Nature Concours Section(s) CNU Profil Labo d

Arleo, Angelo

177

Psychiatric Symptoms in Alpha-Mannosidosis  

ERIC Educational Resources Information Center

Alpha-mannosidosis is characterized by mild to moderate intellectual disability (ID), moderate to severe neurosensory hearing loss, frequent infections, psychomotor disturbances and skeletal dysmorphism. For the first time, a panel of nine alpha-mannosidosis patients with psychiatric symptoms is presented. The clinical picture has several…

Malm, D.; Pantel, J.; Linaker, O. M.

2005-01-01

178

Alpha-thalassemia in two Mediterranean populations.  

PubMed

We used restriction endonuclease analysis to determine the incidence of alpha-thalassemia in two Mediterranean islands. In a random population sample, the gene frequency of deletion-type alpha-thalassemia-2 (-alpha) was 0.18 in Sardinians and 0.07 in Greek Cypriots. All cases were the rightward crossover type. From these frequencies and the known incidence of hemoglobin-H disease in these populations, we calculated the frequency of the alpha-thalassemia-1 genotype (--) and determined that it was low. We also found that beta-thalassemia homozygotes in sardinia have a higher incidence of alpha-thalassemia than normals and beta thalassemia heterozygotes because a significantly greater number of these homozygotes are also homozygous for the alpha-thalassemia-2 lesion. These findings support the theory that coinheritance of alpha-thalassemia mitigates the severity of beta-thalassemia and suggest that the protection is most pronounced when two alpha-globin genes are deleted. PMID:7093530

Pirastu, M; Lee, K Y; Dozy, A M; Kan, Y W; Stamatoyannopoulos, G; Hadjiminas, M G; Zachariades, Z; Angius, A; Furbetta, M; Rosatelli, C; Cao, A

1982-08-01

179

27 CFR 21.95 - Alpha terpineol.  

Code of Federal Regulations, 2011 CFR

...and Firearms 1 2011-04-01 2011-04-01 false Alpha terpineol. 21.95 Section 21.95 Alcohol, Tobacco...ALCOHOL AND RUM Specifications for Denaturants § 21.95 Alpha terpineol. (a) Boiling point at 752mm...

2011-04-01

180

Coefficient Alpha Bootstrap Confidence Interval under Nonnormality  

ERIC Educational Resources Information Center

Three different bootstrap methods for estimating confidence intervals (CIs) for coefficient alpha were investigated. In addition, the bootstrap methods were compared with the most promising coefficient alpha CI estimation methods reported in the literature. The CI methods were assessed through a Monte Carlo simulation utilizing conditions…

Padilla, Miguel A.; Divers, Jasmin; Newton, Matthew

2012-01-01

181

Commentary on Coefficient Alpha: A Cautionary Tale  

ERIC Educational Resources Information Center

The general use of coefficient alpha to assess reliability should be discouraged on a number of grounds. The assumptions underlying coefficient alpha are unlikely to hold in practice, and violation of these assumptions can result in nontrivial negative or positive bias. Structural equation modeling was discussed as an informative process both to…

Green, Samuel B.; Yang, Yanyun

2009-01-01

182

Teaching Calculus with Wolfram|Alpha  

ERIC Educational Resources Information Center

This article describes the benefits and drawbacks of using Wolfram|Alpha as the platform for teaching calculus concepts in the lab setting. It is a result of our experiences designing and creating an entirely new set of labs using Wolfram|Alpha. We present the reasoning behind our transition from using a standard computer algebra system (CAS) to…

Dimiceli, Vincent E.; Lang, Andrew S. I. D.; Locke, LeighAnne

2010-01-01

183

27 CFR 21.95 - Alpha terpineol.  

Code of Federal Regulations, 2010 CFR

...and Firearms 1 2010-04-01 2010-04-01 false Alpha terpineol. 21.95 Section 21.95 Alcohol, Tobacco...ALCOHOL AND RUM Specifications for Denaturants § 21.95 Alpha terpineol. (a) Boiling point at 752mm...

2010-04-01

184

Meta-Analysis of Coefficient Alpha  

ERIC Educational Resources Information Center

The meta-analysis of coefficient alpha across many studies is becoming more common in psychology by a methodology labeled reliability generalization. Existing reliability generalization studies have not used the sampling distribution of coefficient alpha for precision weighting and other common meta-analytic procedures. A framework is provided for…

Rodriguez, Michael C.; Maeda, Yukiko

2006-01-01

185

Elementary Processes Underlying Alpha Channeling in Tokamaks  

SciTech Connect

Alpha channeling in tokamaks is speculative, but also extraordinarily attractive. Waves that can accomplish this effect have been identified. Key aspects of the theory now enjoy experimental confirmation. This paper will review the elementary processes of wave-particle interactions in plasma that underlie the alpha channeling effect

NM.J. Fisch

2012-06-15

186

Fatty acylation of alpha z. Effects of palmitoylation and myristoylation on alpha z signaling.  

PubMed

As the first step in an investigation of roles played by fatty acylation of G protein alpha chains in membrane targeting and signal transmission, we inserted monoclonal antibody epitopes, hemagglutinin (HA) or Glu-Glu (EE), at two internal sites in three alpha subunits. At site I, only HA-tagged alpha q and alpha z functioned normally. alpha s, alpha q, and alpha z subunits tagged at site II with the EE epitope showed normal expression, membrane localization, and signaling activity. Using epitope-tagged alpha z, we investigated effects of mutations in sites for fatty acylation. Mutational substitution of Ala for Gly2 (G2A) prevented incorporation of myristate and decreased but did not abolish incorporation of palmitate. Substitution of Ala for Cys3 (C3A) prevented incorporation of palmitate but had no effect on incorporation of myristate. Substitution of Ala for both Gly2 and Cys3 (G2AC3A) prevented incorporation of both myristate and palmitate. All three mutations substantially disrupted association of alpha z with the particulate fraction. Gz-mediated inhibition of adenylyl cyclase, triggered by activation of the D2-dopamine receptor, was, respectively, abolished (G2AC3A), impaired (G2A), and enhanced (C3A). Constitutive inhibition of adenylyl cyclase by alpha z was unchanged (G2AC3A), strongly diminished (G2A), or strongly enhanced (C3A). A nonacylated, mutationally activated alpha z mutant inhibited adenylyl cyclase, although less potently than normally acylated, mutationally activated alpha z. From these findings we conclude: (a) fatty acylations of alpha z increase its association with membranes; (b) myristoylation is not required for palmitoylation of alpha z or for its productive interactions with adenylyl cyclase; (c) palmitoylation is not required for, but may instead inhibit, signaling by alpha z. PMID:7536745

Wilson, P T; Bourne, H R

1995-04-21

187

FACULT DES SCIENCES HUMAINES ET SOCIALES -SORBONNE  

E-print Network

FACULT� DES SCIENCES HUMAINES ET SOCIALES - SORBONNE LICENCE EN SCIENCES HUMAINES ET SOCIALES ANN�E UNIVERSITAIRE 2013-2014 MENTION SCIENCES DE L'�DUCATION L3 Faculté des Sciences humaines et sociales

Pellier, Damien

188

FACULT DES SCIENCES HUMAINES ET SOCIALES -SORBONNE  

E-print Network

FACULT� DES SCIENCES HUMAINES ET SOCIALES - SORBONNE LICENCE EN SCIENCES HUMAINES ET SOCIALES ANN�E UNIVERSITAIRE 2013-2014 MENTION SCIENCES DU Vaillant 92100 Boulogne-Billancourt L3, M1 et M2 Faculté des Sciences

Pellier, Damien

189

NANCY LANGSTON REGULATINGDIETHYLSTILBESTROL (DES), ENDOCRINE DISRUPTORS,  

E-print Network

NANCY LANGSTON REGULATINGDIETHYLSTILBESTROL (DES), ENDOCRINE DISRUPTORS, the retreat from precaution: Nancy Langston, "The Retreat from Precaution: Regulating Diethylstilbestrol (DES), Endocrine is played by endocrine disruptors--industrial pollutants that mimic hormones and alter sexual development

Langston, Nancy

190

SECRETARIAT GENERAL Direction des ressources humaines  

E-print Network

DE SUIVI DES TRAVAUX DU PLAN TRIENNAL DE DEVELOPPEMENT DE L'EMPLOI ET DE L'INSERTION DES PERSONNES de poste sur le site Web du CNRS. Cela permettrait aux professionnels de disposer d'un contact direct

Canet, Léonie

191

Improved peak shape fitting in alpha spectra.  

PubMed

Peak overlap is a recurrent issue in alpha-particle spectrometry, not only in routine analyses but also in the high-resolution spectra from which reference values for alpha emission probabilities are derived. In this work, improved peak shape formulae are presented for the deconvolution of alpha-particle spectra. They have been implemented as fit functions in a spreadsheet application and optimum fit parameters were searched with built-in optimisation routines. Deconvolution results are shown for a few challenging spectra with high statistical precision. The algorithm outperforms the best available routines for high-resolution spectrometry, which may facilitate a more reliable determination of alpha emission probabilities in the future. It is also applicable to alpha spectra with inferior energy resolution. PMID:25497323

Pommé, S; Caro Marroyo, B

2015-02-01

192

Determination of alpha_s from the QCD static energy: an update  

E-print Network

We present an update of our determination of the strong coupling alpha_s from the quantum chromodynamics static energy. This updated analysis includes new lattice data, at smaller lattice spacings and reaching shorter distances, the use of better suited perturbative expressions to compare with data in a wider distance range, and a comprehensive and detailed estimate of the error sources that contribute to the uncertainty of the final result. Our updated value for alpha_s at the Z-mass scale, M_Z, is alpha_s(M_Z)=0.1166^{+0.0012}_{-0.0008}, which supersedes our previous result.

Alexei Bazavov; Nora Brambilla; Xavier Garcia i Tormo; Peter Petreczky; Joan Soto; Antonio Vairo

2014-11-04

193

Minimisation des inductances propres des condensateurs à film métallisé  

NASA Astrophysics Data System (ADS)

In this article, we examine the different factors responsible for the equivalent series inductance in metallized capacitors and we propose structures for capacitors that reduce this inductance. After recalling the structure of metallized capacitors we compare, by experimental measurements, the inductance due to the winding and that one added by the connections. The latter can become preponderant. In order to explain the experimental evolution of the winding impedance vs. frequency, we describe an analytical model which gives the current density in the winding and its impedance. This model enables us to determine the self resonant frequency for different types of capacitors. From where, we can infer the influence of the height of capacitors and their internal and external radius upon performances, It appears that to reduce the equivalent series inductance, it is better to use flat windings and annular windings. Dans cet article nous examinons les différents facteurs responsables de l'inductance équivalente série dans les condensateurs à film métallisé et proposons des géométries de condensateurs qui réduisent cette inductance. Après avoir rappelé la structure des condensateurs à film métallisé, nous comparons, par des mesures expérimentales, l'inductance due au bobinage et l'inductance ajoutée par les connexions. Cette dernière peut devenir prépondérante. Afin d'expliquer l'évolution de l'impédance du bobinage en fonction de la fréquence, nous décrivons un modèle analytique qui donne la densité du courant dans le bobinage et l'impédance de ce dernier. En outre, ce modèle permet de déterminer la fréquence de résonance série de divers types de condensateurs ce qui permet de déduire l'influence de la hauteur des condensateurs et de leurs rayons interne et externe sur les performances. Il apparaît ainsi que, pour diminuer l'inductance équivalente série, il vaut mieux employer des bobinages plats et des bobinages annulaires.

Joubert, Ch.; Rojat, G.; Béroual, A.

1995-07-01

194

Etude des modes Raman de dformation angulaire des CH2 dans le polythylne  

E-print Network

. Abenoza Laboratoire de Spectroscopie Raman I, Université des Sciences et Techniques du Languedoc, 34060597 Etude des modes Raman de déformation angulaire des CH2 dans le polyéthylène Luu Dang Vinh, M spectres Raman d'échantillons de polyéthylène semi-cristallins ayant des cristallinités et des taux d

Boyer, Edmond

195

Alpha1 and Alpha2 Integrins Mediate Invasive Activity of Mouse Mammary Carcinoma Cells through Regulation of Stromelysin-1 Expression  

SciTech Connect

Tumor cell invasion relies on cell migration and extracellular matrix proteolysis. We investigated the contribution of different integrins to the invasive activity of mouse mammary carcinoma cells. Antibodies against integrin subunits {alpha}6 and {beta}1, but not against {alpha}1 and {alpha}2, inhibited cell locomotion on a reconstituted basement membrane in two-dimensional cell migration assays, whereas antibodies against {beta}1, but not against a6 or {alpha}2, interfered with cell adhesion to basement membrane constituents. Blocking antibodies against {alpha}1 integrins impaired only cell adhesion to type IV collagen. Antibodies against {alpha}1, {alpha}2, {alpha}6, and {beta}1, but not {alpha}5, integrin subunits reduced invasion of a reconstituted basement membrane. Integrins {alpha}1 and {alpha}2, which contributed only marginally to motility and adhesion, regulated proteinase production. Antibodies against {alpha}1 and {alpha}2, but not {alpha}6 and {beta}1, integrin subunits inhibited both transcription and protein expression of the matrix metalloproteinase stromelysin-1. Inhibition of tumor cell invasion by antibodies against {alpha}1 and {alpha}2 was reversed by addition of recombinant stromelysin-1. In contrast, stromelysin-1 could not rescue invasion inhibited by anti-{alpha}6 antibodies. Our data indicate that {alpha}1 and {alpha}2 integrins confer invasive behavior by regulating stromelysin-1 expression, whereas {alpha}6 integrins regulate cell motility. These results provide new insights into the specific functions of integrins during tumor cell invasion.

Lochter, Andre; Navre, Marc; Werb, Zena; Bissell, Mina J

1998-06-29

196

Article original Hydratation des micelles de casine  

E-print Network

15 septembre 1999) Abstract -- Casein micelle solvation and fractal structure of milk aggregatesArticle original Hydratation des micelles de caséine et structure fractale des agrégats et des gels the fractal theory. A relationship is observed between the hydration of casein particles, the structure

Boyer, Edmond

197

LA VITESSE DE REMONTE DES SPERMATOZODES  

E-print Network

cas les spermatozoïdes atteignent le pavillon en moins de 20 minutes. STARKE (1949) approuve les spermatozoïdes par unité de longueur. En effet, en maintenant un fragment des trompes de Fallope (2 mm) par une

Boyer, Edmond

198

Bioinformatique BTVStockage des donnees Bioinformatique BTV  

E-print Network

Bioinformatique BTVStockage des donn´ees Bioinformatique BTV Stockage des donn´ees Jean #12;Bioinformatique BTVStockage des donn´ees Plan Plan 1 Introduction 2 Format de stockage texte 3´ees Format de stockage texte Stockage au format texte Stockage au format texte 8 / 64 #12;Bioinformatique

Richer, Jean-Michel

199

Nonlinear interface dynamos with alpha -quenching  

NASA Astrophysics Data System (ADS)

There exist various mechanisms capable of limiting the magnitude of the (presumably) dynamo-generated, large-scale solar magnetic field. One such mechanism is the so-called ``alpha -quenching''. The underlying idea is that the Lorentz force associated with the dynamo-generated magnetic fields impedes the small scale, turbulent fluid motions giving rise to the so-called ``alpha -effect'' (the production of poloidal from toroidal fields in the framework of mean-field dynamo theory). In mean-field models, a popular ---yet essentially ad hoc--- prescription for alpha -quenching consists in replacing the coefficient (alpha ) of the alpha -effect source term in the dynamo equations by an expression of the form alpha -> alpha (B) =alpha_0 /(1+(|B|/B_eq)(2)) , where alpha_0 is a measure of the strength of the alpha -effect in the linear regime, and B_eq is the equipartition field strength, based on the kinetic energy of the turbulent, convective fluid motions (B_eq ~ 10(4) G at the base of the solar convection zone). In principle, such ``Weak Quenching'' allows the production of magnetic fields of roughly equipartition strength, as demonstrated by the numerous conventional mean-field dynamo models making use of eq. (1), or some close variant, published to date. Vainshtein & Cattaneo (1992, ApJ 393, 165) and Gruzinov & Diamond (1995, Phys. Plasmas 2, 1941) have argued, however, that alpha -quenching should be described by alpha -> alpha (B) =alpha_0 /(R_m(|B|/B_eq)(2)) where R_m is a magnetic Reynolds number based on the microscopic properties of the flow (R_m>> 1 for solar interior conditions). This now describes a much stronger form of alpha -quenching, and, with R_m>> 1, could be fatal to large-scale dynamo action, in the sense that the dynamo could only produce magnetic fields of strength << B_eq. This is in marked contradiction with the demands set by recent models of bipolar magnetic region emergence, which require field strengths of order 10x B_eq ~ 10(5) G for the observed latitudes and tilt of emergence to be adequately reproduced. In this contribution, we investigate the circumstances under which interface dynamos can avoid alpha -quenching, either in the ``Weak'' or ``Strong'' forms defined above. In interface dynamos the alpha -effect is assumed to operate within the solar convective envelope, while the strongest magnetic fields are generated by shearing below the core-envelope interface (Parker 1993, ApJ 408, 707; Charbonneau & MacGregor, submitted to ApJ). This spatial segregation of the alpha -effect source region is the key to avoiding alpha -quenching. This is illustrated using a few nonlinear, kinematic interface dynamo solutions applicable to the Sun.

Charbonneau, P.; MacGregor, K. B.

1996-05-01

200

Genetics Home Reference: Mucolipidosis III alpha/beta  

MedlinePLUS

... literature OMIM Genetic disorder catalog Conditions > Mucolipidosis III alpha/beta On this page: Description Genetic changes Inheritance ... definitions Reviewed October 2014 What is mucolipidosis III alpha/beta? Mucolipidosis III alpha/beta is a slowly ...

201

77 FR 44511 - Airworthiness Directives; Alpha Aviation Concept Limited Airplanes  

Federal Register 2010, 2011, 2012, 2013, 2014

...2120-AA64 Airworthiness Directives; Alpha Aviation Concept Limited Airplanes AGENCY...new airworthiness directive (AD) for Alpha Aviation Concept Limited Model R2160 Airplanes...identified in this proposed AD, contact Alpha Aviation, 59 Hautapu Road, RD...

2012-07-30

202

Genetics Home Reference: Mucolipidosis II alpha/beta  

MedlinePLUS

... literature OMIM Genetic disorder catalog Conditions > Mucolipidosis II alpha/beta On this page: Description Genetic changes Inheritance ... definitions Reviewed June 2014 What is mucolipidosis II alpha/beta? Mucolipidosis II alpha/beta (also known as ...

203

77 FR 60887 - Airworthiness Directives; Alpha Aviation Concept Limited Airplanes  

Federal Register 2010, 2011, 2012, 2013, 2014

...2120-AA64 Airworthiness Directives; Alpha Aviation Concept Limited Airplanes AGENCY...new airworthiness directive (AD) for Alpha Aviation Concept Limited Model R2160 Airplanes...information identified in this AD, contact Alpha Aviation, 59 Hautapu Road, RD 1,...

2012-10-05

204

Who Is at Risk for Alpha-1 Antitrypsin Deficiency?  

MedlinePLUS

... NHLBI on Twitter. Who Is at Risk for Alpha-1 Antitrypsin Deficiency? Alpha-1 antitrypsin (AAT) deficiency occurs in all ethnic ... substances. Rate This Content: Next >> October 11, 2011 Alpha-1 Antitrypsin Deficiency Clinical Trials Clinical trials are ...

205

What Does It Mean to Be an Alpha-1 Carrier?  

MedlinePLUS

... CSL Behring Talecris Biotherapeutics The mission of the Alpha-1 Foundation is to provide the leadership and ... more information, visit: www.alpha-1foundation.org. The Alpha-1 Association is the leading national patient membership ...

206

alpha-Crystallin can Function as a Molecular Chaperone  

Microsoft Academic Search

The alpha-crystallins (alphaA and alphaB) are major lens structural proteins of the vertebrate eye that are related to the small heat shock protein family. In addition, crystallins (especially alphaB) are found in many cells and organs outside the lens, and alphaB is overexpressed in several neurological disorders and in cell lines under stress conditions. Here I show that alpha-crystallin can

Joseph Horwitz

1992-01-01

207

Lucid dreaming and alpha activity: a preliminary report.  

PubMed

10 good dream recallers spent 2 nights in the sleep lab during which they were awakened 4 times per night from REM sleep, twice during their highest alpha activity in REM, and twice during low REM alpha. 5 were given alpha feedback training prior to sleep onset. Arousals from high alpha REM sleep yielded significantly higher lucidity ratings. Alpha feedback had no effect upon lucidity or REM alpha levels. Similarities between lucid dreams and meditative phenomena are discussed. PMID:7162915

Ogilvie, R D; Hunt, H T; Tyson, P D; Lucescu, M L; Jeakins, D B

1982-12-01

208

Autoregulation of I kappa B alpha activity.  

PubMed Central

Transcription factor NF-kappa B regulates the expression of a plethora of genes. The activity of NF-kappa B proteins is regulated by I kappa B proteins. We report that induction of I kappa B alpha, a member of the I kappa B family of proteins, is preceded by activation of NF-kappa B complex. The promoter of the I kappa B alpha gene contains a kappa B site that is directly involved in its induction by the NF-kappa B complex. Degradation of I kappa B alpha protein precedes activation of NF-kappa B DNA binding activity, whereas newly synthesized I kappa B alpha protein inhibits NF-kappa B activity. If the degradation of I kappa B alpha is prevented, the induction of DNA binding activity of NF-kappa B complex is severely curtailed. These data suggest the existence of an autoregulatory loop whereby I kappa B alpha regulates the activity of transcription factor NF-kappa B, which in turn regulates the I kappa B alpha activity. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 6 PMID:8278379

Chiao, P J; Miyamoto, S; Verma, I M

1994-01-01

209

Alpha-Particle Condensation in Nuclear Systems  

E-print Network

The onset of quartetting, i.e. alpha-particle condensation, in symmetric nuclear matter is studied with the help of an in-medium modified four nucleon equation. It is found that at very low density quartetting wins over pairing, because of the strong binding of the alpha-particles. The critical temperature can reach values up to around 6 MeV. Also the disappearance of alpha-particles with increasing density, i.e. the Mott transition, is investigated. In finite nuclei the Hoyle state, that is the 0_2^+ of 12C, is identified as an "alpha-particle condensate" state. It is conjectured that such states also exist in heavier n alpha-nuclei, like 16O, 20Ne, etc. For instance the 6-th 0^+ state of 16O at 15.1 MeV is identified from a theoretical analysis as being a strong candidate for an alpha condensate state. Exploratory calculations are performed for the density dependence of the alpha condensate fraction at zero temperature to address the suppression of the four-particle condensate below nuclear-matter density. Possible quartet condensation in other systems is discussed briefly

Y. Funaki; T. Yamada; H. Horiuchi; G. Röpke; P. Schuck; A. Tohsaki

2008-09-03

210

Lyman alpha radiation in external galaxies  

NASA Technical Reports Server (NTRS)

The Ly alpha line of atomic hydrogen is often a luminous component of the radiation emitted by distant galaxies. Except for those galaxies which have a substantial central source of non-stellar ionizing radiation, most of the Ly alpha radiation emitted by galaxies is generated within regions of the interstellar medium which are photoionized by starlight. Conversely, much of the energy radiated by photoionized regions is carried by the Ly alpha line. Only hot, massive stars are capable of ionizing hydrogen in the interstellar medium which surrounds them, and because such stars are necessarily short-lived, Ly alpha emission traces regions of active star formation. Researchers argue that the strength of the Ly alpha emission observed from external galaxies may be used to estimate quantitatively the dust content of the emitting region, while the Ly alpha line profile is sensitive to the presence of shock waves. Interstellar dust particles and shock waves are intimately associated with the process of star formation in two senses. First, both dust particles and shock waves owe their existence to stellar activity; second, they may both serve as agents which facilitate the formation of stars, shocks by triggering gravitational instabilities in the interstellar gas that they compress, and dust by shielding star-forming molecular clouds from the ionizing and dissociative effects of external UV radiation. By using Ly alpha observations as a probe of the dust content in diffuse gas at high redshift, we might hope to learn about the earliest epochs of star formation.

Neufeld, David A.; Mckee, Christopher F.

1990-01-01

211

association des naturalistes de la  

E-print Network

influencées par les invasions marines de l'Eocène moyen/supérieur. Les Argiles Plastiques de Provins chenal/argilessables dépôts marins dépôts continentaux Marnes à Pholadomia ludensis Le caractère majeur de ces dépôts est leur constituées de débris de plantes transportés ; (2) des matériaux plus fins liés aux bordures des chenaux et

Paris-Sud XI, Université de

212

Lyman Alpha Spicule Observatory (LASO)  

NASA Technical Reports Server (NTRS)

The Lyman Alpha Spicule Observatory (LASO) sounding rocket will observe smallscale eruptive events called "Rapid Blue-shifted Events" (RBEs) [Rouppe van der Voort et al., 2009], the on-disk equivalent of Type-II spicules, and extend observations that explore their role in the solar coronal heating problem [De Pontieu et al., 2011]. LASO utilizes a new and novel optical design to simultaneously observe two spatial dimensions at 4.2" spatial resolution (2.1" pixels) over a 2'x2' field of view with high spectral resolution of 66mAngstroms (33mAngstroms pixels) across a broad 20Angstrom spectral window. This spectral window contains three strong chromospheric and transition region emissions and is centered on the strong Hydrogen Lyman-a emission at 1216Angstroms. This instrument makes it possible to obtain new data crucial to the physical understanding of these phenomena and their role in the overall energy and momentum balance from the upper chromosphere to lower corona. LASO was submitted March 2011 in response to the ROSES SHP-LCAS call.

Chamberlin, Phillip C.

2011-01-01

213

Glucosylation of alpha-butyl- and alpha-octyl-D-glucopyranosides by dextransucrase and alternansucrase from Leuconostoc mesenteroides.  

PubMed

For the first time, glucosylation of alpha-butyl- and alpha-octylglucopyranoside was achieved using dextransucrase (DS) of various specificities, and alternansucrase (AS) from Leuconostoc mesenteroides. All the glucansucrases (GS) tested used alpha-butylglucopyranoside as acceptor; in particular, DS produced alpha-D-glucopyranosyl-(1-->6)-O-butyl-alpha-D-glucopyranoside and alpha-D-glucopyranosyl-(1-->6)-alpha-D-glucopyranosyl-(1-->6)-O-butyl-alpha-D-glucopyranoside. In contrast, alpha-octylglucopyranoside was glucosylated only by AS which was shown to be the most efficient catalyst. The conversion rates, obtained with this enzyme at sucrose to acceptor molar ratio of 2:1 reached 81 and 61% for alpha-butylglucopyranoside and alpha-octylglucopyranoside, respectively. Analyses obtained from liquid chromatography coupled with mass spectrometry revealed that different series of alpha-alkylpolyglucopyranosides regioisomers of increasing polymerization degree can be formed depending on the specificity of the catalyst. PMID:12681910

Richard, Gaëtan; Morel, Sandrine; Willemot, René-Marc; Monsan, Pierre; Remaud-Simeon, Magali

2003-04-22

214

Paternité des articles et intérêts concurrents : une analyse des recommandations aux auteurs des journaux traitant de pratique pharmaceutique  

PubMed Central

RÉSUMÉ Contexte : La présence d’auteurs honorifiques et fantômes ainsi que les intérêts concurrents représentent des difficultés bien documentées, liées à la publication d’articles scientifiques. Il existe des lignes directrices encadrant la rédaction et la publication de manuscrits scientifiques, notamment celles de l’International Committee of Medical Journal Editors (ICMJE). Objectifs : L’objectif principal de cette étude descriptive et transversale visait à recenser les instructions portant sur la paternité des articles et les intérêts concurrents provenant des recommandations aux auteurs des journaux traitant de pratique pharmaceutique. L’objectif secondaire visait à déterminer des mesures correctrices pour une paternité des articles plus transparente. Méthode : La recherche a débuté par l’identification des journaux traitant de pratique pharmaceutique. La consultation des instructions aux auteurs des journaux a permis ensuite de recenser les recommandations destinées à éviter les problèmes de paternité des articles et d’intérêts concurrents. Finalement, les membres de l’équipe de recherche se sont consultés afin de définir des mesures correctrices possibles à l’intention des chercheurs. Résultats : Des 232 journaux traitant de pharmacie, 33 ont été définis comme traitant de pratique pharmaceutique. Un total de 24 (73 %) journaux mentionnaient suivre la politique de l’ICMJE, 14 (42 %) demandaient aux auteurs de remplir un formulaire de déclaration d’intérêts concurrents au moment de la soumission de l’article, 17 (52 %) présentaient une définition de la qualité d’auteur et 5 (15 %) demandaient de détailler les contributions de chaque auteur. Une grille de 40 critères a été élaborée pour définir l’attribution du statut d’auteur. Conclusion : Moins de la moitié des journaux demandait aux auteurs de transmettre un formulaire de déclaration des intérêts concurrents au moment de la soumission d’un article et seulement la moitié des journaux avait donné une définition de la qualité d’auteur. La publication scientifique de travaux sur les pratiques pharmaceutiques n’est pas à l’abri des manques de transparence liés à la publication. L’utilisation d’une grille décrivant la contribution de chaque auteur et la publication en ligne des travaux peuvent contribuer à limiter ces risques. PMID:24970938

Courbon, Ève; Tanguay, Cynthia; Lebel, Denis; Bussières, Jean-François

2014-01-01

215

Facult des arts et des sciences Dpartement de psychologie  

E-print Network

Formulaire d'inscription D.Psy (Option neuropsychologie clinique) V.00 3-220-1-4 Identification de l - Neurosciences des systèmes 3 PSY7413 - �valuation neuropsy. enfant/adolescent. 3 PSY7414 - �valuation neuropsy. adulte/aîné 3 PSY7416 - Neuropsychologie méthodes d'intervention 3 PSY7425 - Syndromes

Parrott, Lael

216

Plan de cours Facult des arts et des sciences  

E-print Network

'organisation des Protistes libres et parasites (Algues, Protozoaires). On soulignera les relations évolutives entre. 1966. Les algues d'Eau douce 1: Les Algues vertes 1968. " " " " 2: Les algues jaunes et brunes 1970. " " " " 3: Les algues bleues et rouges De Puytorac, P. et al. 1987. Précis de protistologie. Boubée

Parrott, Lael

217

Amlioration des plantes Evolution des caractristiques de la graine  

E-print Network

'évolution de l'humidité du capitule et des graines de 25 variétés de tournesol (Helianthus annuus L.), de la of 25 sunflower (Helianthus annuus L.) varieties were followed from flowering to maturity, the oil

Paris-Sud XI, Université de

218

Collagen alpha5 and alpha2(IV) chain coexpression: analysis of skin biopsies of Alport patients.  

PubMed

Alport syndrome is a collagen type IV disease caused by mutations in the COL4A5 gene with the X-linked form being most prevalent. The resultant alpha5(IV) collagen chain is a component of the glomerular and skin basement membranes (SBMs). Immunofluorescent determination of the alpha5(IV) chain in skin biopsies is the procedure of choice to identify patients. In 30% of patients, however, the mutant protein is still found in the SBM resulting in a normal staining pattern. In order to minimize or eliminate false results, we compared the distribution of the alpha2(IV) chain (another SBM component) and the alpha5(IV) chain by standard double label immunofluorescence (IF) and by confocal laser scanning microscopy. The study was performed on 55 skin biopsies of patients suspected of Alports and five normal control specimens. In normal skin, IF showed the classical linear pattern for both collagens along the basement membrane. Additionally, decreased alpha5(IV) was found in the bottom of the dermal papillary basement membrane. Confocal analysis confirmed the results and show alpha5(IV) focal interruptions. In suspected patients, both techniques showed the same rate of abnormal alpha5(IV) expression: segmental in women and absent in men. Our results show a physiological variation of alpha5(IV) location with focal interruptions and decreased expression in the bottom of the dermal basement membrane. Comparison of alpha5(IV) with alpha2(IV) expression is simple and eliminates technical artifacts. PMID:17554254

Patey-Mariaud de Serre, N; Garfa, M; Bessiéres, B; Noël, L H; Knebelmann, B

2007-08-01

219

Fibrinogen {alpha} genes: Conservation of bipartite transcripts and carboxy-terminal-extended {alpha} subunits in vertebrates  

SciTech Connect

All three well-studied subunits of the clotting protein fibrinogen ({alpha}, {beta}, {gamma}) share N-terminal structural homologies, but until recently only the {beta} and {gamma} chains were recognized as having similar globular C-termini. With the discovery of an extra exon in the human fibrinogen {alpha} gene (exon VI), a minor form of the {alpha} subunit ({alpha}{sub E}) with an extended {beta}- and {gamma}-like C-terminus has been identified. In the present study, the polymerase chain reaction has been used to identify sequences that encode counterparts to {alpha}{sub E} in chicken, rabbit, rat, and baboon. The basic six-exon structure of the fibrinogen {alpha} genes is shown to be conserved among mammals and birds, as are the intron positions. Bipartite transcripts - still bearing an intron prior to the last exon - are found among the products of the various vertebrate fibrinogen {alpha} genes. The last exon represents the largest conserved segment of the gene and, in each species examined, encodes exactly 236 amino acids. The C-termini of these {alpha}{sub E} chains align without a single gap and are between 76 and 99% identical. Since the exon VI-encoded domain of {alpha}{sub E} is as well conserved as the corresponding regions of the {beta} and {gamma} chains, it follows that it is equally important and that {alpha}{sub E}-fibrinogen plays a vital, if as-yet unrecognized physiological role. 21 refs., 7 figs., 1 tab.

Fu, Y.; Cao, Y.; Hertzberg, K.M.; Grieninger, G. [Lindsley F. Kimball Research Inst. of the New York Blood Center, NY (United States)] [Lindsley F. Kimball Research Inst. of the New York Blood Center, NY (United States)

1995-11-01

220

Strong absorption model analysis of alpha scattering  

NASA Astrophysics Data System (ADS)

Angular distribution of alpha particles at several energies, E(sub alpha) = 21 approx. 85.6 MeV from a number of nuclei between Ni-20 and Sn-119, extending to wide angular range up to approx. 160 C in some cases, have been analyzed in terms of three-parameter strong absorption model of Frahn and Venter. Interaction radius and surface diffuseness are obtained from the parameter values rendering the best fit to the elastic scattering data. The inelastic scattering of alpha particles from a number of nuclei, leading to quadrupole and octupole excitations has also been studied giving the deformation parameters (beta sub L).

Rahman, M. A.; Chandrapaul, S.; Sengupta, H. M.; Rahman, M.

1991-07-01

221

Alpha cluster structure in 56Ni  

NASA Astrophysics Data System (ADS)

The inelastic ?-scattering experiment on 56Ni in inverse kinematics was performed at an incident energy of 50 MeV/u at GANIL. A very high multiplicity for ?-particle emission was observed with our phase-space limited experimental set-up. The maximum observed multiplicity, which cannot be explained by means of the statistical decay model, amounted to seven. The ideal classical gas model at kT = 3 MeV fairly well reproduced the experimental momentum distribution and multiplicity of alpha particles. This result strongly suggests that an alpha-gas state in 56Ni may be excited via inelastic alpha scattering.

Akimune, H.; Fujiwara, M.; Gibelin, J.; Harakeh, M. N.; Achouri, L.; Bagchi, S.; Bastin, B.; Boretzky, K.; Bouzomita, H.; Caceres, L.; Damoy, S.; Delaunay, F.; Fernández-Domínguez, B.; Caamano, M.; Garg, U.; Grinyer, G. F.; Kalantar-Nayestanaki, N.; Kamalou, O.; Khan, E.; Krasznahorkay, A.; Lhoutellier, G.; Lukyanov, S.; Mazurek, K.; Najafi, M.; Pancin, J.; Penionzkhevich, Y.; Perrot, L.; Raabe, R.; Rigollet, C. E.; Roger, T.; Sambi, S.; Savajols, H.; Senoville, M.; Stodel, C.; Suen, L.; Thomas, J. C.; van de Walle, J.; Vandebrouck, M.

2013-04-01

222

Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G protein  

Microsoft Academic Search

BACKGROUND & AIMS: Tumor necrosis factor alpha (TNF-alpha) inhibits collagen gene expression in cultured fibroblasts. By binding to cell surface receptors, TNF-alpha promotes signals within the cells. The purpose of this study was to investigate the role played by G proteins in TNF-alpha-induced inhibition of collagen gene expression.METHODS: Effect of TNF-alpha on collagen alpha 1(I) messenger RNA (mRNA) level was

I Hernandez-Munoz; P de la Torre; JA Sanchez-Alcazar; I Garcia; E Santiago; MT Munoz-Yague; JA Solis-Herruzo

1997-01-01

223

Les caracteristiques des immigrants, l'effondrement de la TI et leur effet sur les gains initiaux des immigrants  

Microsoft Academic Search

En fondant notre recherche sur des donnees administratives, nous nous demandons 1) si l'evolution des caracteristiques des immigrants, notamment l'augmentation de la proportion d'immigrants ayant un niveau de scolarite universitaire et de celle des immigrants dans la categorie des < travailleurs qualifies de l'immigration economique >, ont contribue favorablement a l'augmentation des gains initiaux des immigrants dans les annees 1990

Garnett Hou Feng Picot

2009-01-01

224

Latina Voices of Des Moines.  

ERIC Educational Resources Information Center

This dissertation examines the lives of Hispanic women living in Des Moines and includes their views of problems and opportunities involved in living in that city. Interviews were conducted with 24 Latino women over the age of 17 who had been in the area for over 2 years. Findings indicate that learning to speak English was the single most…

Taylor, P. Dawn

225

PERFORMANCE DES ORGANISATIONS TRANSVERSALES HOSPITALIERES  

E-print Network

organizations, the Mobile Geriatrics Teams (MGTs). The findings draw on action research involving the 14 MGTs, Intangible Capital, Mobile Geriatrics Teams. Au cours des années 2000, le législateur a affirmé sa volonté d

Boyer, Edmond

226

Convex and alpha-prestarlike subordination chains  

NASA Astrophysics Data System (ADS)

In this paper we consider convex subordination chains (c.s.c.) and alpha-prestarlike subordination chains ([alpha]-p.s.c.) over (0,1] on the unit disc in the complex plane. We obtain sufficient conditions for a mapping f(z,t) to be an [alpha]-p.s.c. over (0,1], which generalize a well-known result of Ruscheweyh [St. Ruscheweyh, Convolutions in Geometric Function Theory, Les Presses de l'Universite de Montreal, 1982]. We also obtain sufficient conditions for injectivity for nonanalytic mappings on the unit disc, and give certain examples of [alpha]-c.s.c. over (0,1] on the unit disc.

Kohr, Gabriela; Mocanu, Petru T.; Serb, Ioan

2007-08-01

227

Radioimmunotherapy with alpha-particle emitting radionuclides.  

PubMed

An important consideration in the development of effective strategies for radioimmunotherapy is the nature of the radiation emitted by the radionuclide. Radionuclides decaying by the emission of alpha-particles offer the possibility of matching the cell specific reactivity of monoclonal antibodies with radiation with a range of only a few cell diameters. Furthermore, alpha-particles have important biological advantages compared with external beam radiation and beta-particles including a higher biological effectiveness, which is nearly independent of oxygen concentration, dose rate and cell cycle position. In this review, the clinical settings most likely to benefit from alpha-particle radioimmunotherapy will be discussed. The current status of preclinical and clinical research with antibodies labeled with 3 promising alpha-particle emitting radionuclides - (213)Bi, (225)Ac, and (211)At - also will be summarized. PMID:15640792

Zalutsky, M R; Pozzi, O R

2004-12-01

228

Nuclear diagnostic for fast alpha particles  

DOEpatents

This invention relates generally to high energy confined plasmas and more particularly is directed to measuring the velocity distribution of confined energetic alpha particles resulting from deuterium-tritium fusion reactions in a confined energetic plasma.

Grisham, L.R.; Post, D.E. Jr.; Dawson, J.M.

1983-11-23

229

La planification préalable des soins pour les patients en pédiatrie  

PubMed Central

RÉSUMÉ Les progrès médicaux et technologiques ont permis d’ac-croître les taux de survie et d’améliorer la qualité de vie des nourrissons, des enfants et des adolescents ayant des maladies chroniques mettant la vie en danger. La planifi-cation préalable des soins inclut le processus relié aux discussions sur les traitements essentiels au maintien de la survie et la détermination des objectifs des soins de longue durée. Les dispensateurs de soins pédiatriques ont l’obligation éthique d’assimiler cet aspect des soins médicaux. Le présent document de principes vise à aider les dispensateurs de soins à discuter de la planification préalable des soins des patients pédiatriques dans diverses situations. La planification préalable des soins exige des communications efficaces afin de clarifier les objectifs des soins et de s’entendre sur les traitements pertinents ou non pour réaliser ces objectifs, y compris les mesures de réanimation et les mesures palliatives.

2008-01-01

230

alpha-Picoline from Rumex obtusifolius L  

Microsoft Academic Search

alpha-PICOLINE has been isolated from the leaves of the dock, Rumex obtusifolius L. There are isolated instances where pyridine and simple derivatives have been found to occur in Nature, for example, pyridine in Aplopappus hartwegi1 and 3-methoxypyridine in Equisetum arvense2. This would appear to be the first record of the presence of alpha-picoline in a natural source. The base was

S. Wilkinson

1958-01-01

231

Measurement of the angle alpha at BABAR  

SciTech Connect

The authors present recent measurements of the CKM angle {alpha} using data collected by the BABAR detector at the PEP-II asymmetric-energy e{sup +}e{sup -} collider at the SLAC National Accelerator Laboratory, operating at the {Upsilon}(4S) resonance. They present constraints on {alpha} from B {yields} {pi}{pi}, B {yields} {rho}{rho} and B {yields} {rho}{pi} decays.

Perez, A.; /Orsay, LAL

2009-06-25

232

Alpha particle haloes in chlorite and cordierite  

Microsoft Academic Search

Summary  Effects of the impact of natural long-term irradiation with alpha particles in one chamosite and one cordierite sample were\\u000a characterised in detail using electron microprobe, Raman microprobe, optical absorption spectroscopy (cordierite only), and\\u000a transmission electron microscopy (TEM; cordierite only) analysis. In both cases, the impact of 4He cores (alpha particles) that were emitted from actinide-bearing mineral inclusions has caused the

L. Nasdala; M. Wildner; R. Wirth; N. Groschopf; D. C. Pal; A. Möller

2006-01-01

233

Alpha-emitters for medical therapy workshop  

SciTech Connect

A workshop on ``Alpha-Emitters for Medical Therapy`` was held May 30-31, 1996 in Denver Colorado to identify research goals and potential clinical needs for applying alpha-particle emitters and to provide DOE with sufficient information for future planning. The workshop was attended by 36 participants representing radiooncology, nuclear medicine, immunotherapy, radiobiology, molecular biology, biochemistry, radiopharmaceutical chemistry, dosimetry, and physics. This report provides a summary of the key points and recommendations arrived at during the conference.

Feinendegen, L.E.; McClure, J.J.

1996-12-31

234

Measurement system for alpha emitters in solution  

NASA Astrophysics Data System (ADS)

The measurement of alpha emitter concentrations in solution corresponds to a need felt in particular by laboratories working on actinides and in the spent fuel reprocessing industry. The instrument present here allows this measurement continuously by the use of a new scintillator that is insensitive to corrosive liquids. The extreme thinness of the scintillator guarantees good detection selectivity of alpha particles in the presence of beta and gamma emissions. Examples of uranium-233, plutonium-239 and americium-241 concentration measurements are presented.

Robert, A.; Sella, C.; Heindl, R.

1984-08-01

235

alpha-Manganese Phases containing Technetium99  

Microsoft Academic Search

THE existence of alpha-manganese phases in the zirconium-technetium, niobium-technetium and molybdenum-technetium systems was recently reported by V. B. Compton et al.1. During the course of our investigation of alloy phases involving technetium-99 with transition metals, alpha-manganese phases were found in the binary systems scandium-technetium, titanium-technetium, hafnium-technetium and tantalum-technetium. Pertinent information is given in Table 1. The alloys were made by

D. J. Lam; J. B. Darby; J. W. Downey; L. J. Norton

1961-01-01

236

Transport of Radioactive Material by Alpha Recoil  

SciTech Connect

The movement of high-specific-activity radioactive particles (i.e., alpha recoil) has been observed and studied since the early 1900s. These studies have been motivated by concerns about containment of radioactivity and the protection of human health. Additionally, studies have investigated the potential advantage of alpha recoil to effect separations of various isotopes. This report provides a review of the observations and results of a number of the studies.

Icenhour, A.S.

2005-05-19

237

THE ALPHA SPECTRUM FROM ($gamma$,\\/cap alpha\\/) ON V⁵¹  

Microsoft Academic Search

The alpha -spectra from V⁵¹( gamma , alpha )Sc⁴⁷ are shown ; for 21 and 30 Mev end point betatron energies. Assuming an isotropic angular ; distribution for emitted alphas, total integrated cross sections of 2,4(1 plus ; or minus 0.3) and 6(1 plus or minus 0.3) mb Mev were obtained for 21 and 30 ; Mev energies, respectively. The

M. Kregar; B. Povh

1962-01-01

238

Energy dependence of event shapes and of $\\\\alpha_s$ at LEP 2  

Microsoft Academic Search

Infrared and collinear safe event shape distributions and their mean values are determined using the data taken at ve di erent centre of mass energies above $M_Z$ with the DELPHI detector at LEP. From the event shapes, the strong coupling $\\\\alpha_s$ is extracted in $O(\\\\alpha^2_s)$, NLLA and a combined scheme using hadronisation corrections evaluated with fragmentation model generators as well

P. Abreu; W Adam; T Adye; P Adzic; Z Albrecht; T Alderweireld; G D Alekseev; R Alemany; T Allmendinger; P P Allport; S Almehed; Ugo Amaldi; N Amapane; S Amato; E G Anassontzis; P Andersson; A Andreazza; S Andringa; P Antilogus; W D Apel; Y Arnoud; B Åsman; J E Augustin; A Augustinus; Paul Baillon; P Bambade; F Barão; Guido Barbiellini; R Barbier; Dimitri Yuri Bardin; G Barker; A Baroncelli; Marco Battaglia; M Baubillier; K H Becks; M Begalli; A Behrmann; P Beillière; Yu A Belokopytov; K S Belous; N C Benekos; Alberto C Benvenuti; C Bérat; M Berggren; D Bertini; D Bertrand; M Besançon; F Bianchi; M Bigi; S M Bilenky; M A Bizouard; D Bloch; H M Blom; M Bonesini; W Bonivento; M Boonekamp; P S L Booth; A W Borgland; G Borisov; C Bosio; O Botner; E Boudinov; B Bouquet; C Bourdarios; T J V Bowcock; I Boyko; I Bozovic; M Bozzo; P Branchini; T Brenke; R A Brenner; P Brückman; J M Brunet; L Bugge; T Buran; T Burgsmüller; Brigitte Buschbeck; P Buschmann; S Cabrera; M Caccia; M Calvi; T Camporesi; V Canale; F Carena; L Carroll; Carlo Caso; M V Castillo-Gimenez; A Cattai; F R Cavallo; V Chabaud; M M Chapkin; P Charpentier; L Chaussard; P Checchia; G A Chelkov; R Chierici; P V Chliapnikov; P Chochula; V Chorowicz; J Chudoba; K Cieslik; P Collins; R Contri; E Cortina; G Cosme; F Cossutti; J H Cowell; H B Crawley; D J Crennell; S Crépé; G Crosetti; J Cuevas-Maestro; S Czellar; Martyn Davenport; W Da Silva; A Deghorain; G Della Ricca; P A Delpierre; N Demaria; A De Angelis; Wim de Boer; C De Clercq; B De Lotto; A De Min; L S De Paula; H Dijkstra; Lucia Di Ciaccio; J Dolbeau; K Doroba; M Dracos; J Drees; M Dris; A Duperrin; J D Durand; G Eigen; T J C Ekelöf; Gösta Ekspong; M Ellert; M Elsing; J P Engel; B Erzen; M C Espirito-Santo; E Falk; G K Fanourakis; D Fassouliotis; J Fayot; Michael Feindt; A Fenyuk; P Ferrari; A Ferrer; E Ferrer-Ribas; F Ferro; S Fichet; A Firestone; U Flagmeyer; H Föth; E Fokitis; F Fontanelli; B J Franek; A G Frodesen; R Frühwirth; F Fulda-Quenzer; J A Fuster; A Galloni; D Gamba; S Gamblin; M Gandelman; C García; C Gaspar; M Gaspar; U Gasparini; P Gavillet; E N Gazis; D Gelé; N Ghodbane; I Gil; F Glege; R Gokieli; B Golob; G Gómez-Ceballos; P Gonçalves; I González-Caballero; Gian P Gopal; L Gorn; M Górski; Yu Guz; Valerio Gracco; J Grahl; E Graziani; C Green; H J Grimm; P Gris; G Grosdidier; K Grzelak; M Günther; J Guy; F Hahn; S Hahn; S Haider; A Hallgren; K Hamacher; J Hansen; F J Harris; V Hedberg; S Heising; J J Hernández; P Herquet; H Herr; T L Hessing; J M Heuser; E Higón; S O Holmgren; P J Holt; S Hoorelbeke; M A Houlden; Josef Hrubec; K Huet; G J Hughes; K Hultqvist; J N Jackson; R Jacobsson; P Jalocha; R Janik; C Jarlskog; G Jarlskog; P Jarry; B Jean-Marie; E K Johansson; P E Jönsson; C Joram; P Juillot; F Kapusta; K Karafasoulis; S Katsanevas; E C Katsoufis; R Keränen; Borut P Kersevan; B A Khomenko; N N Khovanskii; A P Kiiskinen; B J King; A Kinvig; N J Kjaer; O Klapp; H Klein; P M Kluit; P Kokkinias; M Koratzinos; V Kostyukhin; C Kourkoumelis; O Kuznetsov; Manfred Krammer; E Kriznic; J Krstic; Z Krumshtein; P Kubinec; J Kurowska; K L Kurvinen; J Lamsa; P Langefeld; V Lapin; J P Laugier; R Lauhakangas; Gerhard Leder; F Ledroit; V Lefébure; L Leinonen; A Leisos; R Leitner; J Lemonne; Georg Lenzen; V Lepeltier; T Lesiak; M Lethuillier; J Libby; D Liko; A Lipniacka; I Lippi; B Lörstad; J G Loken; J H Lopes; J M López; R López-Fernandez; D Loukas; P Lutz; L Lyons; J N MacNaughton; J R Mahon; A Maio; A Malek; T G M Malmgren; S Maltezos; V Malychev; F Mandl; J Marco; R P Marco; B Maréchal; M Margoni; J C Marin; C Mariotti; A Markou; C Martínez-Rivero; F Martínez-Vidal; S Martí i García; N Mastroyiannopoulos; F Matorras; C Matteuzzi; Giorgio Matthiae; J Masik; F Mazzucato; M Mazzucato; M L McCubbin; R McKay; R McNulty; G McPherson; C Meroni; W T Meyer; E Migliore; L Mirabito; Winfried A Mitaroff; U Mjörnmark; T Moa; M Moch; R Møller; K Mönig; M R Monge; X Moreau; P Morettini; G A Morton; U Müller; K Münich; M Mulders; C Mulet-Marquis; R Muresan; W J Murray; B Muryn; Gerald Myatt; T Myklebust; F Naraghi; M Nassiakou; Francesco Luigi Navarria; S Navas; K Nawrocki; P Negri; S Némécek; N Neufeld; N Neumeister; R Nicolaidou; B S Nielsen; M Nikolenko; V P Nomokonov; Ainsley Normand; A Nygren; V F Obraztsov; A G Olshevskii; A Onofre; Risto Orava; G Orazi; K Österberg; A Ouraou; M Paganoni; S Paiano; R Pain; R Paiva; J Palacios; H Palka; T D Papadopoulou; K Papageorgiou; L Pape; C Parkes; F Parodi; U Parzefall; A Passeri; O Passon; M Pegoraro; L Peralta; Manfred Pernicka; A Perrotta; C Petridou; A Petrolini; H T Phillips; F Pierre; M Pimenta; E Piotto; T Podobnik; M E Pol; G Polok; P Poropat; V Pozdnyakov; P Privitera; N Pukhaeva; Antonio Pullia; D Radojicic; S Ragazzi; H Rahmani; P N Ratoff; A L Read; P Rebecchi; N G Redaelli; Meinhard Regler; D Reid

1999-01-01

239

Phase transition induced by lithium insertion in alphaI- and alphaII-VOPO4  

Microsoft Academic Search

Lithium insertion in alphaI-VOPO4 and alphaII-VOPO4, either by chemical or electrochemical route, leads to the same new compound: alphaI-LiVOPO4 (space group P4\\/nmm). The structure, resolved by neutron and synchrotron diffraction, is made up of planes of corner-connected PO4 and VO5 polyhedra, whereas lithium atoms are located between the layers. The reversal of the short vanadyl bond that corresponds to the

N. Dupré; G. Wallez; J. Gaubicher; M. Quarton

2004-01-01

240

{alpha}-states in de Sitter space  

SciTech Connect

Field theory in de Sitter space admits a one-parameter family of vacua determined by a superselection parameter {alpha}. Of these vacua, the Euclidean vacuum uniquely extrapolates to the vacuum of flat Minkowski space. States which resemble the {alpha}-vacua can be constructed as excitations above the Euclidean vacuum. Such states have modes {alpha}(k) which decay faster that k{sup (1-d)/2}. Fields in such states exhibit nonlocal correlations when examined from the perspective of fields in the Euclidean vacuum. The dynamics of such entangled states are fully consistent. If an {alpha}-state with properties that interpolate between an {alpha}-vacuum and the Euclidean vacuum were the initial condition for inflation, a signature for this may be found in a momentum dependent correction to the inflationary power spectrum. The functional formalism, which provides the tool for examining physics in an {alpha}-state, extends to fields of other spin. In particular, the extension to spin-2 may proffer a new class of infrared modifications to gravitational interactions. The implications of superselection sectors for the landscape of string vacua are briefly discussed.

Boer, Jan de [Instituut voor Theoretische Fysica, Valckenierstraat 65, 1018XE Amsterdam (Netherlands); Jejjala, Vishnu; Minic, Djordje [Institute for Particle Physics and Astrophysics, Physics Department, Robeson Hall, Virginia Tech, Blacksburg, Virginia 24061 (United States)

2005-02-15

241

Alpha-dispersion in human tissue  

NASA Astrophysics Data System (ADS)

Beta dispersion is found in living tissue in the kilohertz - megahertz range and is caused by the cellular structure of biological materials with low frequency properties caused by cell membranes. Alpha dispersion is found in the hertz range and the causes are not so well known. Alpha dispersions are the first to disappear when tissue dies. Tissue data have often been based upon excised specimen from animals and are therefore not necessarily representative for human tissue alpha dispersions. Here we present data obtained with non-invasive skin surface electrodes for different segments of the living human body. We found alpha dispersions in all cases; the ankle-wrist results had the smallest. Large alpha dispersions were found where the distance between the electrodes and muscle masses was small, e.g. on the calf. Further studies on electrode technique and reciprocity, electrode positioning, statistical variations, gender, age and bodily constitutions are necessary in order to reveal more about the alpha dispersion, its appearance and disappearance.

Grimnes, Sverre; Martinsen, Ørjan G.

2010-04-01

242

Folding model analysis of alpha radioactivity  

E-print Network

Radioactive decay of nuclei via emission of $\\alpha$ particles has been studied theoretically in the framework of a superasymmetric fission model using the double folding (DF) procedure for obtaining the $\\alpha$-nucleus interaction potential. The DF nuclear potential has been obtained by folding in the density distribution functions of the $\\alpha$ nucleus and the daughter nucleus with a realistic effective interaction. The M3Y effective interaction has been used for calculating the nuclear interaction potential which has been supplemented by a zero-range pseudo-potential for exchange along with the density dependence. The nuclear microscopic $\\alpha$-nucleus potential thus obtained has been used along with the Coulomb interaction potential to calculate the action integral within the WKB approximation. This subsequently yields microscopic calculations for the half lives of $\\alpha$ decays of nuclei. The density dependence and the exchange effects have not been found to be very significant. These calculations provide reasonable estimates for the lifetimes of $\\alpha$ radioactivity of nuclei.

D. N. Basu

2003-07-29

243

Methods for the synthesis and polymerization of .alpha.,.alpha.'-dihalo-p-xylenes  

DOEpatents

The present invention describes an improved method for the polymerization of .alpha.,.alpha.-dihalo-p-xylene's such as the .alpha.,.alpha.'-dihalo-2-methoxy-5-(2-ethylhexyloxy)-xylene's. The procedure for synthesis is based on the specific order of addition of reagents and the use of an anionic initiator that allows control of the molecular weight of the polymer. The molecular weight control allows processability of the polymer which is important for its utility in applications including in light-emitting-diodes, field effect transistors and photovoltaic devices.

Ferraris, John P. (Coppell, TX); Neef, Charles J. (Garland, TX)

2002-07-30

244

Alpha Com eclipse observing campaign  

NASA Astrophysics Data System (ADS)

Drs. Matthew W. Muterspaugh and Gregory W. Henry (Tennessee State University) have requested AAVSO observers' ssistance in monitoring the possible Algol-like binary star alpha Com before, during, and after the eclipse they have predicted for mid-to-late January 2015. The PIs will be using the Fairborn Observatory automated photometric telescopes on Mt. Hopkins, but they are requesting additional observations not only to supplement theirs but also specifically to have good coverage in the event of bad weather at Mt. Hopkins. Alf Com has a 26-year period and is 4.32V at maximum. The expected amplitude of the eclipse is about 0.8 magnitude and the duration somewhere between 28 and 45 hours. The eclipse is predicted for January 25 ± three days (JD 2457047 ± 3). Muterspaugh at al. first calculated the possibility of a 2015 eclipse in 2010 (AJ). Muterspaugh and Henry recently published an article with updated information (arXiv 2014). V and/or R photometry (other bands welcome) is requested, with a minimal cadence of one measurement/2 hours, to make sure the eclipse is caught right as it begins and to ensure having multiple data points on any unseen objects that might eclipse as well. During eclipse, continuous observations are important. Infrared (H-band) observations could be interesting, should the CHARA array image the event. The precision photometry in the weeks before and after the eclipse is requested in order to catch possible evidence for planets or other materials around the eclipsing star. Updated astrometry from the current epoch would greatly improve the eclipse preductions. Charts with comparison star sequence for alf Com may be created using the AAVSO Variable Star Plotter (http://www.aavso.org/vsp). The PIs recommend using the comparison stars HD 113848 (39 Com, HR 4946, HIP 63948, V=5.990, B-V=0.39, F4V) and HD 114520 (HIP 64312, V=6.820, B-V=0.46,F2II). Observations should be submitted to the AAVSO International Database. See AAVSO Alert Notice 506 for full details.

Waagen, Elizabeth O.

2014-12-01

245

GESTION DES PRESQUE ACCIDENTS ET ACCIDENTS MAJEURS : PREMIER BILAN D'UNE ENQUETE SUR DES SITES SEVESO  

E-print Network

GESTION DES PRESQUE ACCIDENTS ET ACCIDENTS MAJEURS : PREMIER BILAN D'UNE ENQUETE SUR DES SITES sur la gestion des presque accidents. Les presque accidents sont associés à la thématique des précurseurs et des signaux faibles, ces signaux qui sont rendus évident seulement une fois que l'accident est

Boyer, Edmond

246

Osmotic fragility test in heterozygotes for alpha and beta thalassaemia.  

PubMed Central

This study shows that the combination of heterozygous beta thalassaemia and deletion heterozygous (-alpha/alpha alpha) or homozygous (-alpha/-alpha) alpha+ thalassaemia may result in the production of erythrocytes which have normal mean volume and haemoglobinisation but decreased osmotic fragility. Based on this finding and previous studies, which have shown that beta thalassaemia screening by the osmotic fragility test may miss a significant proportion of beta thalassaemia heterozygotes, we conclude that beta thalassaemia screening in a population in which both alpha and beta thalassaemia are prevalent should combine the one tube osmotic fragility test with electronic measurement of red blood cell indices in the initial screening process. PMID:4078866

Maccioni, L; Cao, A

1985-01-01

247

UNIVERSIT DE NANTES FACULT DES SCIENCES ET DES TECHNIQUES  

E-print Network

Année 2008 Etude d'une nouvelle famille d'aluminosilicates de baryum et strontium dopés à l'europium . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.1.1 Positionnement des niveaux énergétiques de l'europium et transi- tions observées . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 4.2.1 Dopage à l'europium . . . . . . . . . . . . . . . . . . . . . . . . . 76 4.2.2 Substitution

Paris-Sud XI, Université de

248

Plan de cours Facult des arts et des sciences  

E-print Network

fonctions des molécules du vivant ; expliquer la relation ADN - ARN - protéine ; connaître l'historique de C. Acides nucléiques Acides désoxyribonucléiques [ADN] Acides ribonucléiques [ARN] Réplication de l'ADN D. Transcription et traduction : synthèse protéique Transcription de l'ADN en ARN Traduction

Parrott, Lael

249

Facult des arts et des sciences Dpartement de science politique  

E-print Network

, 1936) ou de � nous la liberté ! (René Clair, 1931) à partir des textes de Karl Marx étudiés en classe théorie sociale, Coll. « Actuel Marx Confrontation », 2007. 23 janvier ­ Karl Marx et Friedrich Engels ­ L'idéologie - - LECTURES Karl Marx, La Sainte Famille ou Critique de la critique critique, Contre Bruno Bauer et consorts

Parrott, Lael

250

Comparaison des intentions entrepreneuriales des étudiants : France –Pays arabes  

Microsoft Academic Search

A partir d'une grille de lecture dérivée du modèle psychosocial du comportement planifié d'Ajzen, nous étudions les déterminons des intentions entrepreneuriales affichées par les étudiants en France et dans trois pays arabes, Algérie, Liban et Tunisie. Nous observons que les niveaux mesurés de ces intentions sont très différents d'un pays à l'autre et nous essayons d'expliquer ces divergences à partir

J. P. Boissin; B. Branchet; R. Benredjem; J. Schaaper

2009-01-01

251

volution des perceptions gustatives volution des perceptions gustatives  

E-print Network

tannins se lient aux protéines et forment des complexes insolubles totalement indigestes. En outre, les enzymes digestives sont également neutralisées par les aliments trop riches en tannins. La faculté de pour les végétaux [5]. Alors que la fabrication de grosses molécules de polyphénols comme les tannins

Paris-Sud XI, Université de

252

Cancer radioimmunotherapy with alpha-emitting nuclides.  

PubMed

In lymphoid malignancies and in certain solid cancers such as medullary thyroid carcinoma, somewhat mixed success has been achieved when applying radioimmunotherapy (RIT) with beta-emitters for the treatment of refractory cases. The development of novel RIT with alpha-emitters has created new opportunities and theoretical advantages due to the high linear energy transfer (LET) and the short path length in biological tissue of alpha-particles. These physical properties offer the prospect of achieving selective tumoural cell killing. Thus, RIT with alpha-emitters appears particularly suited for the elimination of circulating single cells or cell clusters or for the treatment of micrometastases at an early stage. However, to avoid non-specific irradiation of healthy tissues, it is necessary to identify accessible tumoural targets easily and rapidly. For this purpose, a small number of alpha-emitters have been investigated, among which only a few have been used for in vivo preclinical studies. Another problem is the availability and cost of these radionuclides; for instance, the low cost and the development of a reliable actinium-225/bismuth-213 generator were probably determining elements in the choice of bismuth-213 in the only human trial of RIT with an alpha-emitter. This article reviews the literature concerning monoclonal antibodies radiolabelled with alpha-emitters that have been developed for possible RIT in cancer patients. The principal radio-immunoconjugates are considered, starting with physical and chemical properties of alpha-emitters, their mode of production, the possibilities and difficulties of labelling, in vitro studies and finally, when available, in vivo preclinical and clinical studies. PMID:15841373

Couturier, Olivier; Supiot, Stéphane; Degraef-Mougin, Marie; Faivre-Chauvet, Alain; Carlier, Thomas; Chatal, Jean-François; Davodeau, François; Cherel, Michel

2005-05-01

253

Identification of sequence segments forming the alpha-bungarotoxin binding sites on two nicotinic acetylcholine receptor alpha subunits from the avian brain.  

PubMed

The relationship between neuronal alpha-bungarotoxin binding proteins (alpha BGTBPs) and nicotinic acetylcholine receptor function in the brain of higher vertebrates has remained controversial for over a decade. Recently, the cDNAs for two homologous putative ligand binding subunits, designated alpha BGTBP alpha 1 and alpha BGTBP alpha 2, have been isolated on the basis of their homology to the N terminus of an alpha BGTBP purified from chick brain. In the present study, a panel of overlapping synthetic peptides corresponding to the complete chick brain alpha BGTBP alpha 1 subunit and residues 166-215 of the alpha BGTBP alpha 2 subunits were tested for their ability to bind 125I-alpha BGT. The sequence segments corresponding to alpha BGTBP alpha 1-(181-200) and alpha BGTBP alpha 2-(181-200) were found to consistently and specifically bind 125I-alpha BGT. The ability of these peptides to bind alpha BGT was significantly decreased by reduction and alkylation of the Cys residues at positions 190/191, whereas oxidation had little effect on alpha BGT binding activity. The relative affinities for alpha BGT of the peptide sequences alpha BGTBP alpha 1-(181-200) and alpha BGTBP alpha 2-(181-200) were compared with those of peptides corresponding to the sequence segments Torpedo alpha 1-(181-200) and chick muscle alpha 1-(179-198). In competition assays, the IC50 for alpha BGTBP alpha 1-(181-200) was 20-fold higher than that obtained for the other peptides (approximately 2 versus 40 microM). These results indicate that alpha BGTBP alpha 1 and alpha BGTBP alpha 2 are ligand binding subunits able to bind alpha BGT at sites homologous with nAChR alpha subunits and that these subunits may confer differential ligand binding properties on the two alpha BGTBP subtypes of which they are components. PMID:1869552

McLane, K E; Wu, X D; Schoepfer, R; Lindstrom, J M; Conti-Tronconi, B M

1991-08-15

254

Evaluation des connaissances des parents sur les bronchiolites aiguës  

PubMed Central

Les infections respiratoires (IR) constituent la deuxième cause de mortalité infantile au Maroc, dû en partie à l'absence d'information et de sensibilisation. Le but de ce travail était d’évaluer les connaissances des parents sur la bronchiolite aiguë, infection respiratoire très fréquente. Nous avons réalisé une enquête basée sur un questionnaire, auprès de parents de nourrissons consultants pour toux, avec ou sans gêne respiratoire. 180 parents ont été inclus dans l’étude. Les parents pensaient que l'infection respiratoire était secondaire au climat froid (96%); seuls 4% ont évoqué une origine infectieuse. Aucun des parents ne savait que le lavage des mains était un moyen de prévention de la transmission. Les parents ont majoritairement répondu que la kinésithérapie respiratoire ne servait à rien (65%), et qu'elle était nocive (24.5%). Ce manque de connaissances fondamentales en matière d'IR et de bronchiolite en particulier, devrait inciter à entreprendre un programme de sensibilisation PMID:25328606

Gueddari, Widad; Tazi, Abderrahmane; Ouardi, Amine; Nani, Samira; Zineddine, Abdelhadi

2014-01-01

255

Partager : des technologies de pointe au service de la société  

ScienceCinema

Médecine, climatologie, métrologie et informatique, les techniques utilisées par le LHC trouvent déjà des répercussions dans d?autres domaines scientifiques. Utilisant des techniques inédites, la physique des particules en fait bénéficier la société toute entière.

None

2011-10-06

256

Identification of a novel bile acid in swans, tree ducks, and geese: 3alpha,7alpha,15alpha-trihydroxy-5beta-cholan-24-oic acid.  

PubMed

By HPLC, a taurine-conjugated bile acid with a retention time different from that of taurocholate was found to be present in the bile of the black-necked swan, Cygnus melanocoryphus. The bile acid was isolated and its structure, established by (1)H and (13)C NMR and mass spectrometry, was that of the taurine N-acyl amidate of 3alpha,7alpha,15alpha-trihydroxy-5beta-cholan-24-oic acid. The compound was shown to have chromatographic and spectroscopic properties that were identical to those of the taurine conjugate of authentic 3alpha,7alpha,15alpha-trihydroxy-5beta-cholan-24-oic acid, previously synthesized by us from ursodeoxycholic acid. By HPLC, the taurine conjugate of 3alpha,7alpha,15alpha-trihydroxy-5beta-cholan-24-oic acid was found to be present in 6 of 6 species in the subfamily Dendrocygninae (tree ducks) and in 10 of 13 species in the subfamily Anserinae (swans and geese) but not in other subfamilies in the Anatidae family. It was also not present in species from the other two families of the order Anseriformes. 3alpha,7alpha,15alpha-Trihydroxy-5beta-cholan-24-oic acid is a new primary bile acid that is present in the biliary bile acids of swans, tree ducks, and geese and may be termed 15alpha-hydroxy-chenodeoxycholic acid. PMID:16648547

Kakiyama, Genta; Iida, Takashi; Goto, Takaaki; Mano, Nariyasu; Goto, Junichi; Nambara, Toshio; Hagey, Lee R; Schteingart, Claudio D; Hofmann, Alan F

2006-07-01

257

FACULTE DES SCIENCES UNIVERSITE DE GENEVE REGLEMENT D'ORGANISATION DE LA FACULTE DES SCIENCES  

E-print Network

FACULTE DES SCIENCES UNIVERSITE DE GENEVE REGLEMENT D'ORGANISATION DE LA FACULTE DES SCIENCES règlement d'organisation de la Faculté, en vue de son approbation par le rectorat ; d) peut proposer au décanat des modifications des règlements et plans d'études ainsi que du règlement d'organisation de la

Halazonetis, Thanos

258

FACULTE DES SCIENCES UNIVERSITE DE GENEVE REGLEMENT D'ORGANISATION DE LA FACULTE DES SCIENCES  

E-print Network

FACULTE DES SCIENCES UNIVERSITE DE GENEVE REGLEMENT D'ORGANISATION DE LA FACULTE DES SCIENCES Au règlement d'organisation de la Faculté, en vue de son approbation par le rectorat ; d) peut proposer au décanat des modifications des règlements et plans d'études ainsi que du règlement d'organisation de la

Rochaix, Jean-David

259

La transmission des textes mathmatiques : l'exemple des lments d'Euclide Bernard VITRAC  

E-print Network

1 La transmission des textes mathématiques : l'exemple des �léments d'Euclide Bernard VITRAC Les'erreurs d'inattention par lassitude, facilité de corrections parfois abusives3. I. Les �léments d'Euclide Le cas des �léments d'Euclide, en treize Livres est, à bien des égards, exemplaire : · le traité a connu

Boyer, Edmond

260

MTHODOLOGIE D'ANALYSE DES PHNOMNES EXTRMES : LE CAS DES CYCLONES TROPICAUX  

E-print Network

M�THODOLOGIE D'ANALYSE DES PH�NOM�NES EXTR�MES : LE CAS DES CYCLONES TROPICAUX Karl HOARAU et.hoarau@u-cergy.fr Résumé Avec le changement climatique, beaucoup de scientifiques impliqués dans l'étude des cyclones futures. Avant que les chercheurs ne tentent d'extrapoler l'activité des cyclones extrêmes dans un climat

Paris-Sud XI, Université de

261

Répartitions modales urbaines, externalités et instauration de péages. Le cas des externalités de congestion et des \\  

Microsoft Academic Search

[fre] Répartitions modales urbaines, externalités et instauration de péages. Le cas des externalités de congestion et des « externalités modales croisées ». . Cet article se propose d'analyser les répartitions des usagers entre l'automobile et les bus dans le cadre des déplacements urbains domicile-travail. Dans ce contexte, l'objectif de cet article est de mettre en lumière deux types d'externalités générées

François Mirabel

1999-01-01

262

TUDE DES PROPRITS PHYSIQUES DES COUCHES MINCES PHOTOSENSIBLES DE SULFURE DE CADMIUM  

E-print Network

757 �TUDE DES PROPRI�T�S PHYSIQUES DES COUCHES MINCES PHOTOSENSIBLES DE SULFURE DE CADMIUM Par G. - Pour reconnaître si les cellules au sulfure de cadmium étaient aptes à la photométrie des petits flux substances photo- conductrices, le sulfure de cadmium est l'une des plus sensibles. On entend par là d

Paris-Sud XI, Université de

263

La culture en action des enseignants LA CULTURE EN ACTION DES ENSEIGNANTS  

E-print Network

La culture en action des enseignants 1 LA CULTURE EN ACTION DES ENSEIGNANTS REVUE DES SCIENCES DE L'action située, cet article propose une analyse de la cognition et de la culture en action des enseignants. La en classe et la possibilité d'une culture partagée ; la troisième sur les processus de transmission

Paris-Sud XI, Université de

264

Alpha Channeling in Rotating Plasma with Stationary Waves  

SciTech Connect

An extension of the alpha channeling effect to supersonically rotating mirrors shows that the rotation itself can be driven using alpha particle energy. Alpha channeling uses radiofrequency waves to remove alpha particles collisionlessly at low energy. We show that stationary magnetic fields with high n? can be used for this purpose, and simulations show that a large fraction of the alpha energy can be converted to rotation energy.

A. Fetterman and N.J. Fisch

2010-02-15

265

EEG alpha power and alpha power asymmetry in sleep and wakefulness  

E-print Network

sleep, particularly during rapid eye movement ~REM! sleep. These results suggest that patterns during dreaming. During sleep, alpha power was highest during slow-wave sleep and lowest during REM sleep and sleeping are considered. Descriptors: Electroencephalography, Alpha, Sleep, REM sleep, Human Individual

Wisconsin at Madison, University of

266

Experimental and Theoretical Electron Density Distribution of Alpha,Alpha-Trehalose Dihydrate  

Technology Transfer Automated Retrieval System (TEKTRAN)

Alpha,alpha-rehalose is of interest because of its cryoprotective and antidessicant properties, and because it possesses various technical anomalies such as 13C NMR spectra that give misleading indications of intramolecular structural symmetry. It is a non-reducing disaccharide, with the glycosidic...

267

Effects of $\\alpha$-cluster breaking on 3$\\alpha$ cluster structures in $^{12}$C  

E-print Network

To clarify the effects of $\\alpha$-cluster breaking on 3$\\alpha$ cluster structures in $^{12}$C, we investigate $^{12}$C using a hybrid model that combines the Brink-Bloch cluster model with the $p_{3/2}$ subshell closure wave function. We have found that $\\alpha$-cluster breaking caused by spin-orbit force significantly changes cluster structures of excited $0^{+}$ states through orthogonality to lower states. Spatially developed cluster components of the $0^{+}_{2}$ state are reduced. The $0^{+}_{3}$ state changes from a vibration mode in the bending motion of three $\\alpha$ clusters to a chain-like 3$\\alpha$ structure having an open triangle configuration. As a result of these structure changes of $0^{+}$ states, the band assignment for the $2^{+}_{2}$ state is changed by the $\\alpha$-cluster breaking effect. Namely, in model calculations without the $\\alpha$-cluster breaking effect, the $0^{+}_{2}$ state is assigned to be the band-head of the $2^{+}_{2}$ state. However, when we incorporate $\\alpha$-cluste...

Suhara, Tadahiro

2014-01-01

268

Amyloid formation and disaggregation of {alpha}-synuclein and its tandem repeat ({alpha}-TR)  

SciTech Connect

Research highlights: {yields} Formation of the {alpha}-synuclein amyloid fibrils by [BIMbF{sub 3}Im]. {yields} Disaggregation of amyloid fibrils by epigallocatechin gallate (EGCG) and baicalein. {yields} Amyloid formation of {alpha}-synuclein tandem repeat ({alpha}-TR). -- Abstract: The aggregation of {alpha}-synuclein is clearly related to the pathogenesis of Parkinson's disease. Therefore, detailed understanding of the mechanism of fibril formation is highly valuable for the development of clinical treatment and also of the diagnostic tools. Here, we have investigated the interaction of {alpha}-synuclein with ionic liquids by using several biochemical techniques including Thioflavin T assays and transmission electron microscopy (TEM). Our data shows a rapid formation of {alpha}-synuclein amyloid fibrils was stimulated by 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide [BIMbF{sub 3}Im], and these fibrils could be disaggregated by polyphenols such as epigallocatechin gallate (EGCG) and baicalein. Furthermore, the effect of [BIMbF{sub 3}Im] on the {alpha}-synuclein tandem repeat ({alpha}-TR) in the aggregation process was studied.

Bae, Song Yi; Kim, Seulgi; Hwang, Heejin; Kim, Hyun-Kyung; Yoon, Hyun C.; Kim, Jae Ho [Department of Molecular Science and Technology, Graduate School of Interdisciplinary Programs, Ajou University, Suwon 443-749 (Korea, Republic of)] [Department of Molecular Science and Technology, Graduate School of Interdisciplinary Programs, Ajou University, Suwon 443-749 (Korea, Republic of); Lee, SangYoon, E-mail: sangyoon@ajou.ac.kr [Chronic Inflammatory Disease Research Center, School of Medicine, Ajou University, Suwon 443-749 (Korea, Republic of)] [Chronic Inflammatory Disease Research Center, School of Medicine, Ajou University, Suwon 443-749 (Korea, Republic of); Kim, T. Doohun, E-mail: doohunkim@ajou.ac.kr [Department of Molecular Science and Technology, Graduate School of Interdisciplinary Programs, Ajou University, Suwon 443-749 (Korea, Republic of)

2010-10-01

269

Correcting Coefficient Alpha for Correlated Errors: Is [alpha][K]a Lower Bound to Reliability?  

ERIC Educational Resources Information Center

When errors of measurement are positively correlated, coefficient alpha may overestimate the "true" reliability of a composite. To reduce this inflation bias, Komaroff (1997) has proposed an adjusted alpha coefficient, ak. This article shows that ak is only guaranteed to be a lower bound to reliability if the latter does not include correlated…

Rae, Gordon

2006-01-01

270

Structure and anti-acetylcholinesterase activity of 4 alpha-(hydroxymethyl)-4 alpha-demethylterritrem B.  

PubMed

The structure of a metabolite produced on incubation of territrem B (1) with rat liver microsomes has been established to be 4 alpha-(hydroxymethyl)-4 alpha-demethylterritrem B (5). Compound 5 was a potent inhibitor of electric eel acetylcholinesterase (AChE) (E.C. 3.1.1.7). PMID:9287420

Peng, F C

1997-08-01

271

PARASITES ORDINAIRES DES PORCS EN FRANCE ISOLEMENT DES SOUCHES POUR INFESTATIONS EXPRIMENTALES  

E-print Network

PARASITES ORDINAIRES DES PORCS EN FRANCE DIAGNOSTIC ISOLEMENT DES SOUCHES POUR INFESTATIONS' - Amboise R�SUM� Un survol sur les parasites ordinaires des porcs en France est présenté en distinguant les'Oesophagos- tomum est présenté. SUMMARY ORDINARY PARASITES OF SWINE IN FRANCE ; DIAGNOSIS ; ISOLATION

Boyer, Edmond

272

Aide aux doctorants pour la participation des Aide aux doctorants pour la participation des colloques  

E-print Network

Aide aux doctorants pour la participation à des colloques Aide aux doctorants pour la participation à des colloques retour Formation doctorale Aide aux doctorants pour la participation à des colloques aide vient compléter les financements déjà prévus par les laboratoires et les �coles doctorales pour

Di Girolami, Cristina

273

Difficile convergence des archives ouvertes en SIC # Difficile convergence des archives ouvertes  

E-print Network

Difficile convergence des archives ouvertes en SIC # Difficile convergence des archives ouvertes en Paris R�SUM�. L'article rend compte d'un test de moissonnage pour quatre archives ouvertes sélectionnées'identification des archives ouvertes SIC sur le répertoire international OpenDOAR, est ensuite approfondie à partir

Paris-Sud XI, Université de

274

COLORIMTRIE DES LED : INCERTITUDES ET INFLUENCE DU COURANT LECTRIQUE 17 Colorimtrie des LED  

E-print Network

COLORIM�TRIE DES LED : INCERTITUDES ET INFLUENCE DU COURANT �LECTRIQUE 17 N. POUSSET Colorimétrie des LED : incertitudes et influence du courant électrique LEDs colorimetry: uncertainties proximale, et indices de rendu des couleurs) de sources d'éclairage à LED, du LNE-INM/Cnam, est décrit. Les

Paris-Sud XI, Université de

275

Evolution des types cellulaires du lait de brebis (race Churra) en fonction des dnombrements cellulaires totaux  

E-print Network

Evolution des types cellulaires du lait de brebis (race Churra) en fonction des dénombrements) en fonction des dénombrements cellulaires totaux est étudiée dans le lait de 91 brebis de race Churra traite du matin, obtenu sur 91 brebis de race Churra : 42 appartenant à une exploitation avec traite

Paris-Sud XI, Université de

276

Electronique organique: Emission de lumire bleue dans des OLEDs via des excimres intramolculaires.  

E-print Network

Electronique organique: Emission de lumière bleue dans des OLEDs via des excimères ces nouvelles molécules comme couche active dans des diodes organiques électroluminescentes (OLEDs OLEDs. Ces travaux s'intègrent dans la thématique "Composés 3-2spiro pour l'électronique organique

Rennes, Université de

277

Comptes Rendus des JNC 17 -Poitiers 2011 Nouvelle mthode de fabrication des composites fibres naturelles  

E-print Network

Comptes Rendus des JNC 17 - Poitiers 2011 1 Nouvelle méthode de fabrication des composites à fibres method of manufacture of natural fibers composites: Contribution of a paper layer to minimize mécaniques des matériaux composites unidirectionnels à fibres naturelles de chanvre et de lin. L

Paris-Sud XI, Université de

278

DTERMINATION ULTRASONORE DES PROPRITS LASTIQUES ET ANLASTIQUES EN FONCTION DE LA FRACTION VOLUMIQUE DES AMAS  

E-print Network

that the formation of Guinier-Preston zones in alumi- nium-magnesium alloys is accompanied by an increase VOLUMIQUE DES AMAS DE GUINIER-PRESTON DANS DES ALLIAGES ALUMINIUM-MAGN�SIUM C. GAULT Laboratoire de Physique que la formation des amas de Guinier-Preston dans les alliages aluminium-magnésium s'accompagne d

Paris-Sud XI, Université de

279

LE PROBLME DES NOMBRES CONGRUENTS Pierre Colmez  

E-print Network

Fibonacci (1175­1240). Théorème 3 (Fermat (1601­1665)). --- 1 n'est pas un nombre congruent. #12; 2 PIERRE COLMEZ C'est une des nombreuses utilisations que Fermat a trouvées pour sa méthode 2 de « la des­ centeLE PROBL�ME DES NOMBRES CONGRUENTS par Pierre Colmez Résumé. --- Ce texte est une introduction à la

Colmez, Pierre

280

FAILLES DE SECURITE DES APPLICATIONS WEB  

E-print Network

FAILLES DE SECURITE DES APPLICATIONS WEB PRINCIPES, PARADES ET BONNES PRATIQUES DE DEVELOPPEMENT Référence : Failles de sécurité des applications Web Date de dernière mise à jour : 03/04/2012 Version du-BY-NC-ND Objet du document : Ce document explique les 10 principales failles de sécurité des applications Web

Paris-Sud XI, Université de

281

Oligoclonal repertoire of the CD8 alpha alpha and the CD8 alpha beta TCR-alpha/beta murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells  

PubMed Central

The epithelium of the small intestine in normal euthymic mice contains a large number of intraepithelial lymphocytes (IEL), some of which bear a T cell receptor alpha/beta (TCR-alpha/beta). About half of these TCR- alpha/beta IEL display the CD8 alpha alpha phenotype and the remaining have the CD8 alpha beta or the CD4 phenotypes. To examine whether TCR- alpha/beta IEL have a TCR-beta chain repertoire as diverse as that of TCR-alpha/beta lymph node lymphocytes (LNL), we used a recently described PCR technique that allows a global analysis of the TCR-beta chain repertoire. Within any given mouse, the repertoires expressed in both CD8 alpha alpha and CD8 alpha beta TCR-alpha/beta IEL populations are oligoclonal and nonoverlapping between the two subsets. The clones are largely conserved through the length of the small intestine of the same individual. However, genetically identical individuals raised under indistinguishable environmental conditions display distinct oligoclonal repertoires. Those findings indicate that few cells of CD8 alpha alpha or of the CD8 alpha beta phenotype are responsible for the repopulation of the intestinal epithelium. PMID:7931068

1994-01-01

282

Alpha satellite DNA in neotropical primates (Platyrrhini).  

PubMed

The alpha satellite DNA of Old World (catarrhine) primates usually consists of similar, but not identical, ca. 170 bp sequences repeated tandemly hundreds to thousands of times. The 170 bp monomeric repeats are components of higher-order repeats, many of which are chromosome specific. Alpha satellites are found exclusively in centromeric regions where they appear to play a role in centromere function. We have found that alpha satellite DNA in neotropical (New World; platyrrhine) primates is very similar to its Old World counterpart: it consists of divergent ca. 170 bp subsequences that are arranged in tandem arrays with a ca. 340 bp periodicity. New and Old World alpha satellites share about 64% sequence identity overall, and contain several short sequence motifs that appear to be highly conserved. One exception to the tandemly arrayed 340 bp motif has been found: the major alpha satellite array in Chiropotes satanas (black bearded saki) has a 539 bp repeat unit that consists of a 338 bp dimer together with a duplication of 33 bp of the first monomeric unit and 168 bp of the second monomeric unit. PMID:7988287

Alves, G; Seuánez, H N; Fanning, T

1994-07-01

283

Alpha-particle sensitive test SRAMs  

NASA Technical Reports Server (NTRS)

A bench-level test is being developed to evaluate memory-cell upsets in a test SRAM designed with a cell offset voltage. This offset voltage controls the critical charge needed to upset the cell. The effect is demonstrated using a specially designed 2-micron n-well CMOS 4-kb test SRAM and a Po-208 5.1-MeV 0.61-LET alpha-particle source. This test SRAM has been made sensitive to alpha particles through the use of a cell offset voltage, and this has allowed a bench-level characterization in a laboratory setting. The experimental data are linked to a alpha-particle interaction physics and to SPICE circuit simulations through the alpha-particle collection depth. The collection depth is determined by two methods and found to be about 7 micron. In addition, alpha particles that struck outside the bloated drain were able to flip the SRAM cells. This lateral charge collection was observed to be more than 6 micron.

Buehler, M. G.; Blaes, B. R.

1990-01-01

284

Isospin symmetry in mirror {alpha} decays  

SciTech Connect

We show that a consequence of isospin symmetry, recently discovered in mirror conjugated one-nucleon decays, can be extended to mirror-conjugated {alpha}-particle decays, both virtual and real. For virtual {alpha} decays of bound mirror pairs this symmetry manifests itself as a relation between the asymptotic normalization coefficients (ANCs) of {alpha}-particle overlap integrals. This relation is given by a simple analytical formula that involves {alpha}-particle separation energies and charges of residual nuclei. For bound-unbound mirror pairs, the ANC of a bound nucleus is related to the {alpha} width of the mirror unbound level. For unbound mirror pairs we get a new analytical formula that relates the widths of mirror resonances. We test the validity of these analytical formulas against the predictions of a two-body potential and of a many-body microscopic cluster model for several mirror states in {sup 7}Li-{sup 7}Be, {sup 11}B-{sup 11}C, and {sup 19}F-{sup 19}Ne isotopes. We show that these analytical formulas are valid in many cases but that some deviations can be expected for isotopes with strongly deformed and easily excited cores. In general, the results from microscopic model are not very sensitive to model assumptions and can be used to predict unknown astrophysically relevant cross sections using known information about mirror systems.

Timofeyuk, N. K.; Johnson, R. C. [Department of Physics, School of Electronics and Physical Sciences, University of Surrey, Guildford, Surrey GU2 7XH (United Kingdom); Descouvemont, P. [Physique Nucleaire Theorique et Physique Mathematique, CP229 Universite Libre de Bruxelles, B-1050 Brussels (Belgium)

2007-03-15

285

Measurement of the Strong Coupling Constant Alpha  

NASA Astrophysics Data System (ADS)

The strong coupling constant alpha _{rm s} has been measured from the rate of jet production observed in W events collected by the UA1 detector from proton-antiproton collisions at sqrt{rm s} = 630 GeV at the CERN collider. W bosons are to a first approximation produced by quark-antiquark annihilation at the CERN pp collider. Strong interactions led to hadronic jets emitted with the W. To first order the rate of jet production is proportional to the strong coupling constant. Experimental and theoretical difficulties make the determination of alpha_{rm s} more complicated. The ratio of the number of W events observed with one jet to the number of W events with no jet was measured. This result was then compared to a QCD predicted ratio which was a function of the strong coupling constant. The QCD predicted ratio was calculated using the EKS and ISAJET Monte Carlos in conjunction with a full simulation of the UA1 detector. The value of alpha_{rm s} was varied until the experimental and predicted ratios were equal. The value of alpha_{rm s} was found to be alpha_{ rm s} =.127 +/-.026(stat.) +/-.022(exp. syst.) +/- .025(theor. syst.).

Lindgren, Michael Allen

1990-01-01

286

alpha-nucleus potentials, alpha-decay half-lives, and shell closures for superheavy nuclei  

E-print Network

Systematic alpha-nucleus folding potentials are used to analyze alpha-decay half-lives of superheavy nuclei. Preformation factors of about several per cent are found for all nuclei under study. The systematic behavior of the preformation factors and the volume integrals of the potentials allows to predict alpha-decay energies and half-lives for unknown nuclei. Shell closures can be determined from measured alpha-decay energies using the discontinuity of the volume integral at shell closures. For the first time a double shell closure is predicted for Z_magic = 132, N_magic = 194, and A_magic = 326 from the systematics of folding potentials. The calculated alpha-decay half-lives remain far below one nanosecond for superheavy nuclei with double shell closure and masses above A > 300 independent of the precise knowledge of the magic proton and neutron numbers.

Peter Mohr

2006-11-09

287

Rat plasma alpha 1-inhibitor3: a member of the alpha-macroglobulin family.  

PubMed

The overall mechanism of interaction with proteinases of alpha 1-inhibitor3, a plasma proteinase inhibitor so far specific to the rat, has been shown to be closely similar to that described for alpha-macroglobulins. This mechanism includes: (i) the cleavage of at least one susceptible peptidic bond which leads to structural changes in the molecule. (ii) The cleavage of a putative thiol ester bond in another site of the molecule which permits the covalent linkage of the enzyme. Moreover, fragmentation of alpha 1-inhibitor3 upon heating as observed for alpha-macroglobulin quarter subunits has been demonstrated. The question is raised of the presence of such a molecule in rat plasma in addition to two alpha-macroglobulin species, all of these proteinase inhibitors being antigenically unrelated. PMID:2578988

Esnard, F; Gutman, N; el Moujahed, A; Gauthier, F

1985-03-11

288

Über die ?-Strahlung des Protactiniums  

Microsoft Academic Search

Zusammenfassung 1. Das a-strahlende Element Protactinium emittiert, ähnlich wie Radium, Radioactinium, Actinium X, auch sekundäre ß-Strahlen. 2. Es werden Absorptionskurven dieser ß-Strahlen aufgenommen und mit analogen Absorptionskurven der ß-Strahlen des Radioaetiniums verglichen. Die zeitlichen Änderungen der Kurven geben einen weiteren Beweis dafür, daß die ß-Strahlung beim Protactinium nicht etwa von irgendwelchen Verunreinigungen herrührt. 3. Es wird die Intensität der ß-Strahlen

Otto Hahn; Aristid v. Grosse

1928-01-01

289

MOISISSURES TOXINOGNES DES FOURRAGES ENSILS  

E-print Network

'ici démontré la production de mycotoxines dans les ensilages ; cet auteur a mis en évidence la présence de i à éventuelle de patuline dans la ration consommée; en effet, cette mycotoxine peut être élaborée par'une recherche systéma- tique de cette mycotoxine dans des échantillons d'ensilages dont la contamination s

Boyer, Edmond

290

Erste Symptome des Organizational Burnout  

Microsoft Academic Search

\\u000a Die ersten Anzeichen des Organizational Burnout sind weder von der betroffenen Organisation oder Institution noch von einem\\u000a externen Analysten zu erkennen. So wenig, wie beispielsweise Diabetes. Diese Krankheit kann jahrzehntelang unbemerkt verlaufen.\\u000a Die ersten Symptome sind in der Regel schwach ausgeprägt. Nicht einmal die Hälfte der Bluthochdruckerkrankungen wird erkannt\\u000a – und von diesen wird nur die Hälfte behandelt, weil es

Gustav Greve

291

Diagnostik von Knorpelschäden des Kniegelenks  

Microsoft Academic Search

ZusammenfassungZielstellung  Anliegen der Arbeit war es, die Validität der präoperativen klinischen Untersuchung, der radiologischen Befunde und der MRT bei der Diagnostik chondraler Schäden des Kniegelenks im Vergleich zur Arthroskopie zu bestimmen.Methode  Bei 721 Patienten mit Kniebeschwerden die 3 Monate oder länger andauerten, erfolgte die standardisierte klinische Diagnostik (Grinding-Test), die radiologische Standarddiagnostik (Standaufnahmen und Patella-Axial-Aufnahme) sowie die MRT-Untersuchung (T1- und T2-Wichtung). Alle Patienten wurden nachfolgend

G. Spahn; R. Wittig; E. Kahl; H. M. Klinger; T. Mückley; G. O. Hofmann

2007-01-01

292

Geschichtspolitische Verwerfungen des Post-Kommunismus.  

E-print Network

??Die vorliegende Diplomarbeit aus dem Feld der kritischen Museum Studies beschäftigt sich mit kuratorischen Strategien der Darstellung des Kommunismus im Kontext zeithistorischer Ausstellungen seit 1989.… (more)

Ziaja, Luise Adriane

2013-01-01

293

Le point sur l'inegalite des gains et sur la remuneration des jeunes durant les annees 90  

Microsoft Academic Search

De nombreux auteurs ont fait etat de l'inegalite de plus en plus prononcee des gains d'emploi particulierement chez les hommes. Le present article enrichit notre connaissance des tendances de l'inegalite des gains en repondant a trois questions. Premierement, comment l'inegalite des gains des personnes occupees a-t-elle evolue dans les annees 90? Notre etude indique que, du milieu des annees 80

Garnett Picot

1998-01-01

294

Microdosimetry for Targeted Alpha Therapy of Cancer  

PubMed Central

Targeted alpha therapy (TAT) has the advantage of delivering therapeutic doses to individual cancer cells while reducing the dose to normal tissues. TAT applications relate to hematologic malignancies and now extend to solid tumors. Results from several clinical trials have shown efficacy with limited toxicity. However, the dosimetry for the labeled alpha particle is challenging because of the heterogeneous antigen expression among cancer cells and the nature of short-range, high-LET alpha radiation. This paper demonstrates that it is inappropriate to investigate the therapeutic efficacy of TAT by macrodosimetry. The objective of this work is to review the microdosimetry of TAT as a function of the cell geometry, source-target configuration, cell sensitivity, and biological factors. A detailed knowledge of each of these parameters is required for accurate microdosimetric calculations. PMID:22988479

Huang, Chen-Yu; Guatelli, Susanna; Oborn, Bradley M.; Allen, Barry J.

2012-01-01

295

Analysis of H-alpha flare spectra  

NASA Technical Reports Server (NTRS)

Spectrographs of the H-alpha line taken at 15 second intervals from the event of 5 Sept. 1973 were interpreted by comparison with synthetic profiles. A sequence of 27 high resolution H alpha profiles was obtained from the second brightest flare kernel. The profiles were generally self reversed with a maximum peak intensity of 1.16 x continuum and a maximum central intensity of .91 x continuum. The line characteristics such as red and violet peak intensities and positions, center shifts and wing intensities were tabulated. Synthetic H-alpha profiles were generated from a finite layer assuming simple parameteric forms for the source function and velocity field. The velocity chosen always decreased with optical depth and had the same sign. For absorption profiles, bisector shifts were calculated for a variety of velocities. The velocity field and source function were derived as a function of optical depth and time.

Kulander, J. L.

1977-01-01

296

Nuclear diagnostic for fast alpha particles  

DOEpatents

Measurement of the velocity distribution of confined energetic alpha particles resulting from deuterium-tritium fusion reactions in a magnetically contained plasma is provided. The fusion plasma is seeded with energetic boron neutrals for producing, by means of the reaction .sup.10 B (.alpha.,n) .sup.13 N reaction, radioactive nitrogen nuclei which are then collected by a probe. The radioactivity of the probe is then measured by conventional techniques in determining the energy distribution of the alpha particles in the plasma. In a preferred embodiment, diborane gas (B.sub.2 H.sub.6) is the source of the boron neutrals to produce .sup.13 N which decays almost exclusively by positron emission with a convenient half-life of 10 minutes.

Grisham, Larry R. (Lawrence Township, Mercer County, NJ); Post, Jr., Douglass E. (Belle Mead, NJ); Dawson, John M. (Pacific Palisades, CA)

1986-01-01

297

Ultraviolet observations of alpha Aurigae from Copernicus  

NASA Technical Reports Server (NTRS)

Emission lines of L-alpha (1215.67 A) and O VI (1031.94 A) were detected in the spectroscopic binary alpha Aur (Capella) with the Princeton experiment on Copernicus. Temperatures of the emitting regions are inferred to be in excess of 300,000 K. The temperature and emission measure are consistent with a variable source of soft X-rays. If the emission is attributed to the primary star (G5 III), the atmosphere is expanding with velocities of about 20-100 km/s. Such expansion can lead to material within the binary system. The density of interstellar hydrogen inferred from absorption of stellar L-alpha appears to be approximately 0.01 hydrogen atoms per cu cm.

Dupree, A. K.

1975-01-01

298

Synthesis of peptide .alpha.-thioesters  

DOEpatents

Disclosed herein is a new method for the solid phase peptide synthesis (SPPS) of C-terminal peptide .alpha. thioesters using Fmoc/t-Bu chemistry. This method is based on the use of an aryl hydrazine linker, which is totally stable to conditions required for Fmoc-SPPS. When the peptide synthesis has been completed, activation of the linker is achieved by mild oxidation. The oxidation step converts the acyl-hydrazine group into a highly reactive acyl-diazene intermediate which reacts with an .alpha.-amino acid alkylthioester (H-AA-SR) to yield the corresponding peptide .alpha.-thioester in good yield. A variety of peptide thioesters, cyclic peptides and a fully functional Src homology 3 (SH3) protein domain have been successfully prepared.

Camarero, Julio A. (Livermore, CA); Mitchell, Alexander R. (Livermore, CA); De Yoreo, James J. (Clayton, CA)

2008-08-19

299

Alternating current long range alpha particle detector  

DOEpatents

An alpha particle detector, utilizing alternating currents, which is capable of detecting alpha particles from distinct sources. The use of alternating currents allows use of simpler ac circuits which, in turn, are not susceptible to dc error components. It also allows the benefit of gas gain, if desired. In the invention, a voltage source creates an electric field between two conductive grids, and between the grids and a conductive enclosure. Air containing air ions created by collision with alpha particles is drawn into the enclosure and detected. In some embodiments, the air flow into the enclosure is interrupted, creating an alternating flow of ions. In another embodiment, a modulated voltage is applied to the grid, also modulating the detection of ions.

MacArthur, D.W.; McAtee, J.L.

1993-02-16

300

Alternating current long range alpha particle detector  

DOEpatents

An alpha particle detector, utilizing alternating currents, whcih is capable of detecting alpha particles from distinct sources. The use of alternating currents allows use of simpler ac circuits which, in turn, are not susceptible to dc error components. It also allows the benefit of gas gain, if desired. In the invention, a voltage source creates an electric field between two conductive grids, and between the grids and a conductive enclosure. Air containing air ions created by collision with alpha particles is drawn into the enclosure and detected. In some embodiments, the air flow into the enclosure is interrupted, creating an alternating flow of ions. In another embodiment, a modulated voltage is applied to the grid, also modulating the detection of ions.

MacArthur, Duncan W. (Los Alamos, NM); McAtee, James L. (Los Alamos, NM)

1993-01-01

301

Lyman-alpha imagery of Comet Kohoutek  

NASA Technical Reports Server (NTRS)

Electrographic imagery of Comet Kohoutek in the 1100-1500 A wavelength range was obtained from a sounding rocket on Jan. 8, 1974, and from the Skylab space station on 13 occasions between Nov. 26, 1973 and Feb. 2, 1974. These images are predominantly due to Lyman-alpha (1216 A) emission from the hydrogen coma of the comet. The rocket pictures have been calibrated for absolute sensitivity and a hydrogen production rate has been determined. However, the Skylab camera suffered degradation of its sensitivity during the mission, and its absolute sensitivity for each observation can only be estimated by comparison of the comet images with those taken by the rocket camera, with imagery of the geocoronal Lyman-alpha glow, of the moon in reflected Lyman-alpha, and of ultraviolet-bright stars. The rocket and geocoronal comparisons are used to derive a preliminary, qualitative history of the development of the cometary hydrogen coma and the associated hydrogen production rate.

Carruthers, G. R.; Opal, C. B.; Page, T. L.; Meier, R. R.; Prinz, D. K.

1974-01-01

302

The Lyman alpha emission of starburst galaxies  

NASA Technical Reports Server (NTRS)

Nearby starburst galaxies have consistently shown anomalous Ly-alpha/H-beta ratios. It has been suggested that dust, associated with resonant scattering, quenches the Ly-alpha line by a large factor. However, the observed amount of dust can barely account for the large depletion factors. It is proposed here that a much more important effect is the age of the burst. Normal (i.e., case B recombination) ratios are observed if the galaxy is currently undergoing the burst, while anomalous ratios appear when the galaxy is observed in the post-burst phase. Underlying stellar populations in the UV spectra should therefore be older in the latter case. This scenario explains the presence of Ly-alpha in absorption. Implications for deep surveys are also discussed.

Valls-Gabaud, David

1993-01-01

303

Relation entre les caractéristiques des table-bancs et les mesures anthropométriques des écoliers au Benin  

PubMed Central

Introduction Le mobilier scolaire et la posture assise en classe sont souvent impliqués dans l'apparition des douleurs rachidiennes, influant de fait sur la qualité des tâches réalisées par les apprenants. Aucune étude n'a encore vérifié le degré d'adéquation entre les caractéristiques du mobilier et celles des écoliers au Bénin. L'objectif de cette étude transversale est donc de déterminer la relation entre les dimensions des table-bancs utilisées en classe et les mesures anthropométriques des écoliers au Bénin. Methods Elle a été réalisée avec un échantillon probabiliste de 678 écoliers, âgés de 4 à 17 ans. Les mesures anthropométriques des écoliers et les mensurations relatives aux longueurs, largeurs et hauteurs des table-bancs ont été mesurées, puis intégrées aux équations proposées dans la littérature. Les pourcentages des valeurs situées hors des limitesacceptables, dérivées de l'application des équations ont été calculés. Results La largeur et la hauteur des table-bancs utilisées par les écoliers étaient plus élevées (p < 0,05) que les valeurs de référence recommandées par les structures officielles de contrôle et de production des mobiliers scolaires au Bénin. Quel que soit le sexe, il y avait une inadéquation entre la largeur du banc et la longueur fesse-poplité, puis entre la hauteur de la table et la distance coude-bancdes écoliers. Conclusion Les résultats suggèrent de prendre en compte l’évolution des mesures anthropométriques des écoliers dans la confection des table-bancs, afin de promouvoir de bonnes postures assises en classe et de réduire le risque de troubles du rachis. PMID:25317232

Falola, Stève Marjelin; Gouthon, Polycarpe; Falola, Jean-Marie; Fiogbe, Michel Armand; Nigan, Issiako Bio

2014-01-01

304

Solution structure of {alpha}-conotoxin PIA, a novel antagonist of {alpha}6 subunit containing nicotinic acetylcholine receptors  

SciTech Connect

{alpha}-Conotoxin PIA is a novel nicotinic acetylcholine receptor (nAChR) antagonist isolated from Conus purpurascens that targets nAChR subtypes containing {alpha}6 and {alpha}3 subunits. {alpha}-conotoxin PIA displays 75-fold higher affinity for rat {alpha}6/{alpha}3{beta}2{beta}3 nAChRs than for rat {alpha}3{beta}2 nAChRs. We have determined the three-dimensional structure of {alpha}-conotoxin PIA by nuclear magnetic resonance spectroscopy. The {alpha}-conotoxin PIA has an '{omega}-shaped' overall topology as other {alpha}4/7 subfamily conotoxins. Yet, unlike other neuronally targeted {alpha}4/7-conotoxins, its N-terminal tail Arg{sup 1}-Asp{sup 2}-Pro{sup 3} protrudes out of its main molecular body because Asp{sup 2}-Pro{sup 3}-Cys{sup 4}-Cys{sup 5} forms a stable type I {beta}-turn. In addition, a kink introduced by Pro{sup 15} in the second loop of this toxin provides a distinct steric and electrostatic environment from those in {alpha}-conotoxins MII and GIC. By comparing the structure of {alpha}-conotoxin PIA with other functionally related {alpha}-conotoxins we suggest structural features in {alpha}-conotoxin PIA that may be associated with its unique receptor recognition profile.

Chi, Seung-Wook [Protein Analysis and Design Laboratory, Division of Drug Discovery, Korea Research Institute of Bioscience and Biotechnology, Yusong P. O. Box 115, Daejon (Korea, Republic of); Lee, Si-Hyung [Protein Analysis and Design Laboratory, Division of Drug Discovery, Korea Research Institute of Bioscience and Biotechnology, Yusong P. O. Box 115, Daejon (Korea, Republic of); Kim, Do-Hyoung [Protein Analysis and Design Laboratory, Division of Drug Discovery, Korea Research Institute of Bioscience and Biotechnology, Yusong P. O. Box 115, Daejon (Korea, Republic of); Kim, Jae-Sung [Protein Analysis and Design Laboratory, Division of Drug Discovery, Korea Research Institute of Bioscience and Biotechnology, Yusong P. O. Box 115, Daejon (Korea, Republic of); Olivera, Baldomero M. [Department of Biology, University of Utah, Salt Lake City, UT 84112 (United States); McIntosh, J. Michael [Department of Biology, University of Utah, Salt Lake City, UT 84112 (United States); Department of Psychiatry, University of Utah, Salt Lake City, UT 84112 (United States); Han, Kyou-Hoon [Protein Analysis and Design Laboratory, Division of Drug Discovery, Korea Research Institute of Bioscience and Biotechnology, Yusong P. O. Box 115, Daejon (Korea, Republic of)]. E-mail: khhan600@kribb.re.kr

2005-12-30

305

Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha.  

PubMed Central

By in situ hybridization, 44-100% of the blood eosinophils from five patients with hypereosinophilia and four normal subjects exhibited intense hybridization signals for TNF-alpha mRNA. TNF-alpha protein was detectable by immunohistochemistry in blood eosinophils of hypereosinophilic subjects, and purified blood eosinophils from three atopic donors exhibited cycloheximide-inhibitable spontaneous release of TNF-alpha in vitro. Many blood eosinophils (39-91%) from hypereosinophilic donors exhibited intense labeling for macrophage inflammatory protein-1 alpha (MIP-1 alpha) mRNA, whereas eosinophils of normal donors demonstrated only weak or undetectable hybridization signals for MIP-1 alpha mRNA. Most tissue eosinophils infiltrating nasal polyps were strongly positive for both TNF-alpha and MIP-1 alpha mRNA. By Northern blot analysis, highly enriched blood eosinophils from a patient with the idiopathic hypereosinophilic syndrome exhibited differential expression of TNF-alpha and MIP-1 alpha mRNA. These findings indicate that human eosinophils represent a potential source of TNF-alpha and MIP-1 alpha, that levels of expression of mRNA for both cytokines are high in the blood eosinophils of hypereosinophilic donors and in eosinophils infiltrating nasal polyps, that the eosinophils of normal subjects express higher levels of TNF-alpha than MIP-1 alpha mRNA, and that eosinophils purified from the blood of atopic donors can release TNF-alpha in vitro. Images PMID:8514874

Costa, J J; Matossian, K; Resnick, M B; Beil, W J; Wong, D T; Gordon, J R; Dvorak, A M; Weller, P F; Galli, S J

1993-01-01

306

Alpha decay studies near ^100Sn  

NASA Astrophysics Data System (ADS)

Nuclei around the exotic doubly-magic ^100Sn can provide key information to, and serve as rigorous tests of, the nuclear shell model. In particular, the energy splitting between neutron single-particle orbits in this region, the ?d5/2 - ?g7/2, can be extracted from the low-energy excited states in the odd-N Sn isotopes, ideally from ^101Sn. Identification and examination of these nuclei is aided by the presence of an island of alpha and proton radioactivity for nuclei with Z > 50 near ^100Sn. The isotopes ^109Xe and ^105Te were identified at the Holifield Radioactive Ion Beam Facility using the Recoil Mass Spectrometer through the observation of the characteristic alpha decay chain ^109Xe -> ^105Te -> ^101Sn. The efficient identification of the fast ^105Te alpha decay was enabled through the use of digital signal processing using advanced pulse shape analysis alogrithms. The unique double alpha decay pulse provided an ideal tag to observe gamma-ray emission from the excited states of both ^105Te and ^101Sn at approximately 150 and 172 keV, respectively. Both excited states in ^105Te and ^101Sn were populated through alpha decay. The observation of the first excited state in ^101Sn provides the ?d5/2 - ?g7/2 energy splitting. Using the experimental value in shell model calculations suggests an ordering of single particle states in ^101Sn that contradicts previous expectations. The possibility of reaching the ^108Xe -> ^104Te -> ^100Sn alpha decay chain will also be discussed.

Liddick, Sean

2008-10-01

307

Lectin interactions with alpha-galactosylated xenoantigens.  

PubMed

alpha-Galactosylated xenoantigens (Galalpha1-3Galbeta1-4GlcNAcbeta1 and Galalpha1-3Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc) are often detected with the alpha-Gal specific lectin Griffonia simplicifolia 1 isolectin B4 (GS1 B4). However, this lectin exhibits a broad and variable specificity for carbohydrates terminating in alpha-Gal. Thus, both false positive and false negative results may occur when GS1 B4 is used to determine natural antigens in xeno (pig-to-primate) transplantation research. To refine the tools for detecting alpha-galactosylated antigens we have studied the binding of various alpha-galactophilic lectins to alpha-galactosylated neoglycoproteins. The lectins were: Euonymus europaeus agglutinin (EEA), Griffonia simplicifolia 1 isolectin B4 (GS1 B4), Maclura pomifera agglutinin (MPA) and Pseudomonas aeruginosa agglutinin (PA-IL). Although both GS1 B4 and MPA strongly bound glycoconjugates terminating in Gal there seems to be some differentiation in their sugar binding preferences. MPA was the only lectin that showed high affinity for the pentasaccharide Galalpha1-3Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc and for the Galalpha-glycans on non-primate thyroglobulin. The length of the xenoantigenic carbohydrate chain may influence the nature of the inhibition when a simple sugar is used to inhibit GS1 B4 binding to the xenoantigen. Inhibition studies of MPA GS1 B4 interaction further suggest that both lectins attach to the same site of the carbohydrate antigen and that GS1 B4 in addition binds to at least one other site that has no affinity for MPA. When lectins are used for recognition and investigation of natural Galalpha-antigens, we propose that GS1 B4 and MPA should accompany each other. PMID:12060462

Kirkeby, Svend; Moe, Dennis

2002-07-01

308

Etude cytophotomtrique de l'ADN et des nucloprotines des spermatozodes du blier : influence du sjour  

E-print Network

Etude cytophotométrique de l'ADN et des nucléoprotéines des spermatozoïdes du bélier : influence du'un complexe entre l'ADN et la protéine spécifique du spermatozoïde (BNSP) riche en cystéine et en arginine colorabi- lité de l'ADN par le Feulgen sans que la teneur en ADN des spermatozoïdes, mesurée en UV ne

Paris-Sud XI, Université de

309

Thymus ontogeny and the development of TCR alpha beta intestinal intraepithelial lymphocytes.  

PubMed

Murine T cell receptor (TCR) alpha beta intestinal intraepithelial lymphocytes (IEL), which express the CD8 molecule as a homodimer (CD8 alpha alpha), can be divided into two subsets: those which are CD4+ (CD4+CD8+alpha alpha) and those which are CD4- (CD4-CD8+alpha alpha). Here, we demonstrate that most TCR alpha beta CD4+CD8+alpha alpha IEL and TCR alpha beta CD4-CD8+alpha alpha IEL subsets appear to be of thymus origin, as neonatal thymectomy of BALB/c mice on Day 3 nearly eliminated both subsets. To further support this hypothesis, we demonstrate by grafting the thymus of CBF1 (BALB/c x C57BL/6) mice into nude mice that the thymus is capable of generating both TCR alpha beta CD4-CD8+alpha alpha IEL and TCR alpha beta CD4+CD8+alpha alpha IEL. However, which of the two TCR alpha beta IEL subsets is generated depends largely on the age of the thymus. The thymus from fetal up to 2 weeks of age generates predominantly TCR alpha beta CD4-CD8+alpha alpha IEL, but very scant amounts CD4+CD8+alpha alpha IEL. In contrast, the thymus after 2 weeks of age generates very little TCR alpha beta CD4-CD8+alpha alpha IEL, but generates an abundant amount of TCR alpha beta CD4+CD8+alpha alpha IEL. These results are consistent with the observation in euthymic mice that TCR alpha beta CD4-CD8+alpha alpha IEL precede the appearance of TCR alpha beta CD4+CD8+alpha alpha IEL by several weeks, thus further suggesting that the thymus is the major source of both TCR alpha beta IEL subsets. PMID:8660848

Lin, T; Matsuzaki, G; Yoshida, H; Kenai, H; Omoto, K; Umesue, M; Singaram, C; Nomoto, K

1996-07-10

310

Radiological hazards of alpha-contaminated waste  

SciTech Connect

The radiological hazards of alpha-contaminated wastes are discussed in this overview in terms of two components of hazard: radiobiological hazard, and radioecological hazard. Radiobiological hazard refers to human uptake of alpha-emitters by inhalation and ingestion, and the resultant dose to critical organs of the body. Radioecological hazard refers to the processes of release from buried wastes, transport in the environment, and translocation to man through the food chain. Besides detailing the sources and magnitude of hazards, this brief review identifies the uncertainties in their estimation, and implications for the regulatory process.

Rodgers, J.C.

1982-01-01

311

Nouvelles mobilisations productives des territoires autour des ports et des aroports  

E-print Network

'équipe «Territoires de la mondialisation et villes portuaires». #12;Le mode de développement post-industriel se fonde géographique ou l'équipement performant ne suffisent pas aux villes portuaires pour gagner le choix des socio-politiques territorialisés. Les systèmes d'acteurs et d'espaces doivent ainsi évoluer pour mettre

Paris-Sud XI, Université de

312

Study of alpha-methyldopa oxidation by tyrosinase.  

PubMed

The pathway for alpha-methyldopa oxidation to alpha-methyldopachrome, by mushroom tyrosinase, is proposed. Characterization of intermediates in this oxidative reaction and stoichiometry determination have both been undertaken. The steps for alpha-methyldopa transformation into its aminochrome would be: alpha-methyldopa----o-alpha-methyldopaquinone-H+----o-alpha- methyldopaquinone----leuko-alpha-methyldopachrome----alpha- methyldopachrome. The stoichiometry for this conversion corresponded to the equation: 2 o-alpha-methyldopaquinone-H+----alpha-methyldopa + alpha-methyldopachrome. At very acid pH values, another route implying the addition of water to the quinonic ring, competes with the first one. Two chemical pathways can be proposed from alpha-methyldopaquinone-H+, the relative importance of which is determined by the pH. A theoretical and experimental kinetic approach was applied to this oxidative reaction. Rate constants and thermodynamic activation parameters of the chemical steps, have been evaluated. The results obtained confirmed that alpha-methyldopa oxidation by tyrosinase followed a scheme similar to that established for L-dopa and alpha-methylnoradrenaline. PMID:3002882

Jiménez, M; Garcia-Canovas, F; Garcia-Carmona, F; Tudela, J; Iborra, J L

1986-01-01

313

Synthesis of alpha-D-glucosylglycerol by alpha-glucosidase and some of its characteristics.  

PubMed

It has been found that alpha-D-glucosylglycerol (GG) is contained in such traditional Japanese foods brewed by using koji as sake, miso and mirin, and that GG is formed by transglucosylation to glycerol that is produced by yeast with alpha-glucosidase (EC 3.2.1.20) from koji in the sake mash. GG has also been found to consist of three components, 2-O-alpha-D-glucosylglycerol (GG-II), (2R)-1-O-alpha-D-glucosylglycerol (R-GG-I) and (2S)-1-O-alpha-D-glucosylglycerol (S-GG-I). GG was synthesized from a mixture of maltose and glycerol by the batch method, using alpha-glucosidase (transglucosidase L-AMANO). alpha-Glucosidase seemed to be so stable that the amount of GG increased about 5-fold compared with that in the first reaction by the daily addition of maltose for 10 d. Syrupy GG obtained was found to have the following characteristics: about 0.55-fold sweetness compared with sucrose, high thermo-stability, low heat-colorability, low Maillard reactivity, low hygroscopicity, high water-holding capacity, non-cariogenicity and low digestibility. PMID:11055383

Takenaka, F; Uchiyama, H

2000-09-01

314

Factors governing helical preference of peptides containing multiple alpha,alpha-dialkyl amino acids.  

PubMed Central

The presence of multiple alpha,alpha-dialkyl amino acids such as alpha-methylalanine (alpha-aminoisobutyric acid, Aib) leads to predominantly helical structures, either with alpha-helical or 3(10)-helical hydrogen bonding patterns. The crystal structure of emerimicin-(1-9) benzyl ester (Ac-Phe-Aib-Aib-Aib-Val-Gly-Leu-Aib-Aib-OBzl) reported here shows essentially pure alpha-helical character, whereas other similar compounds show predominantly 3(10)-helical structures. The factors that govern helical preference include the inherent relative stability of the alpha-helix compared with the 3(10)-helix, the extra hydrogen bond seen with 3(10)-helices, and the enhanced electrostatic dipolar interaction of the 3(10)-helix when packed in a crystalline lattice. The balance of these forces, when combined with the steric requirements of the amino acid side chains, determines the relative stability of the two helical conformations under a given set of experimental conditions. Images PMID:2296604

Marshall, G R; Hodgkin, E E; Langs, D A; Smith, G D; Zabrocki, J; Leplawy, M T

1990-01-01

315

The alpha-form of the hydroxides of bivalent metals  

NASA Technical Reports Server (NTRS)

X-ray analyses were made of the hydroxides of the bivalent metals. The freshly pptd. hydroxide is usually in the alpha-form, which on standing is converted to another form or other forms. The alpha and c grating dimensions of the alpha-form and the C6-type of Co, Zn, C, Co-Zn and Ni-Zn hydroxides are tabulated. Ni hydroxide does not exhibit an alpha-form. The alpha-Co(OH)2, the blue form, is stabilized by sugar or by the higher alcohols: these compounds do not stabilize alpha-Zn(OH)2.

Feitknecht, W.

1984-01-01

316

Agénésie bilatérale des vésicules séminales et des canaux déférents  

PubMed Central

Résumé L’absence de canaux déférents et de vésicules séminales est une cause très rare d’infertilité masculine qui pose des difficultés d’ordre diagnostique. De plus, son traitement est complexe. Dans le présent article, nous rapportons le cas d’un patient âgé de 43 ans qui a consulté pour infertilité primaire évoluant depuis 5 ans (un conseil génétique a été réalisé) et nous examinons les difficultés diagnostiques et thérapeutiques liées à cette forme particulière d’infertilité. PMID:25132895

Kassogué, Amadou; El Ammari, J. Eddine; Diarra, Alkadri; Amiroune, Driss; Ahsaini, Mustapha; Ouldim, Karim; Traoré, Zacharia; Sqalli, H. Nadia; Tizniti, Siham; Mellas, Soufiane; Tazi, M. Fadl; Khallouk, Abdelhak; El Fassi, M. Jamal; Farih, My Hassan

2014-01-01

317

Thorie des Jeux Et ses Applications  

E-print Network

relance »...) Importance de la théorie des probabilités #12;Un Peu d'Histoire John von Neumann (1903-1957 si cBJohn von Neumann (1944 économique et politique Quelques contributions de J. Von Neumann : Axiomatisation des mathématiques

Giraud, Olivier

318

Titel des Moduls: Brain-Computer Interfacing  

E-print Network

Titel des Moduls: Brain-Computer Interfacing LP (nach ECTS): 9 Kurzbezeichnung: MINF Brain-Computer Interfacing. Sie sind in der Lage, eigenständig die Verfahren der biomedizinischen. In einigen Spezialthemen des Brain- Computer Interfacing haben die Teilnehmer eine vertiefte Kenntnis. Die

Wichmann, Felix

319

MCNP S(. alpha. beta. ) detector scheme  

SciTech Connect

An approximate method to allow S({alpha},{Beta}) thermal collision contributions to point detectors and DXTRAN by Prael has been implemented in MCNP4. The method is described and test results are presented, including some results that indicate inadequacies in the NJOY processing of the nuclear data. 9 refs., 53 figs., 6 tabs.

Hendricks, J.S.; Prael, R.E.

1990-10-01

320

Electron Screening Effects on {alpha}-decay  

SciTech Connect

An open problem in Nuclear Astrophysics concerns the understanding of electron-screening effects on nuclear reaction rates at stellar energies. In this framework, we have proposed to investigate the influence of the electron cloud on {alpha}-decay by measuring Q-values and {alpha}-decay half-lives of fully stripped, H-like and He-like ions. These kinds of measurements have been feasible just recently for highly-charged radioactive nuclides by fragmentation of {sup 238}U at relativistic energies at the FRS-ESR facility at GSI. In this way it is possible to produce, efficiently separate and store highly-charged {alpha}-emitters. Candidates for the proposed investigation were carefully selected and will be studied by using the Schottky Mass Spectroscopy technique. In order to establish a solid reference data set, lifetimes and Q{sub {alpha}}-value measurements of the corresponding neutrals have been performed directly at the FRS, by implanting the separated ions into an active Silicon stopper.

Musumarra, A.; Bonasera, A.; Del Zoppo, A.; Di Pietro, A.; Figuera, P.; Kimura, S.; Lattuada, M.; Pellegriti, M. G.; Scuderi, V.; Torresi, D. [INFN-LNS and University of Catania, Catania (Italy); Farinon, F.; Geissel, H.; Knoebel, R.; Prochazka, A.; Scheidenberger, C. [GSI, Darmstadt (Germany); Justus-Liebig Universitaet, Giessen (Germany); Nociforo, C.; Behr, K.-H.; Bosch, F.; Boutin, D.; Bruenle, A. [GSI, Darmstadt (Germany)] (and others)

2009-08-26

321

Alpha track density using a semiconductor detector  

E-print Network

in the film corresponding to the damage produced in the dielectric by alpha particle passage and etching enhancement. A xenon flash lamp was used as the blue light source (467nm) for a CN densitometer, and a cadmium sulfide (CdS) photoconductive semiconductor...

Hamilton, Ian Scott

1993-01-01

322

EEG alpha power and creative ideation?  

PubMed Central

Neuroscientific studies revealed first insights into neural mechanisms underlying creativity, but existing findings are highly variegated and often inconsistent. Despite the disappointing picture on the neuroscience of creativity drawn in recent reviews, there appears to be robust evidence that EEG alpha power is particularly sensitive to various creativity-related demands involved in creative ideation. Alpha power varies as a function of creativity-related task demands and the originality of ideas, is positively related to an individuals’ creativity level, and has been observed to increase as a result of creativity interventions. Alpha increases during creative ideation could reflect more internally oriented attention that is characterized by the absence of external bottom-up stimulation and, thus, a form of top-down activity. Moreover, they could indicate the involvement of specific memory processes such as the efficient (re-)combination of unrelated semantic information. We conclude that increased alpha power during creative ideation is among the most consistent findings in neuroscientific research on creativity and discuss possible future directions to better understand the manifold brain mechanisms involved in creativity. PMID:23246442

Fink, Andreas; Benedek, Mathias

2014-01-01

323

Serum alpha 1 antitrypsin and pulmonary emphysema.  

PubMed

Using isoelectric focusing (IEF) and radial immunodiffusion (RID) techniques, serum samples from 100 normal healthy adults and 21 patients with pulmonary emphysema were analysed to identify various alpha 1 antitrypsin phenotypes and the serum concentrations. Ten percent of the patients had low serum values. The normal or most common genetic form, MM, is the predominant phenotype in both controls and patients. PMID:8961698

Shahid, A; Siddiqui, A A; Aziz, S; Ansari, M; Zuberi, S J; Waqar, M A

1996-05-01

324

Transformer Recharging with Alpha Channeling in Tokamaks  

SciTech Connect

Transformer recharging with lower hybrid waves in tokamaks can give low average auxiliary power if the resistivity is kept high enough during the radio frequency (rf) recharging stage. At the same time, operation in the hot ion mode via alpha channeling increases the effective fusion reactivity. This paper will address the extent to which these two large cost saving steps are compatible. __________________________________________________

N.J. Fisch

2009-12-21

325

Hematologic Features of Alpha Thalassemia Carriers  

PubMed Central

Alpha thalassemia (?-thal) is relatively common worldwide. Most carriers are defective in either one or two alpha globin genes out of four functional ones, with deletions being more common than point mutations. The hematologic features are very important for the selection of the appropriate molecular tests while determining the genotype. The aim of this study was to compare hematologic features of patients with various types of ? globin mutations. Hematological indices including red blood cells (RBC), hemoglobin concentration (Hb), mean cell volume (MCV), mean cell hemoglobin (MCH), Mean corpuscular hemoglobin concentration (MCHC) and percentage of Hemoglobin (HBA1, HBA2 and HBF) of seven-hundred and twenty two patients presenting ten different ?-thal genotypes were considered. All patients showed reduced MCV and/or MCH values.Moreover, MCV and MCH were lower in patients with two functional alpha globin genes in comparison to patients with one mutated alpha globin gene (P value<0.001). In conclusion, MCV and MCH valuescan be helpful for the selection of the appropriate molecular tests to determine the genotype of alphathalassemia carriers. PMID:24551772

Akhavan-Niaki, Haleh; Youssefi Kamangari, Reza; Banihashemi, Ali; Kholghi Oskooei, Vahid; Azizi, Mandana; Tamaddoni, Ahmad; Sedaghat, Sadegh; Vakili, Mohsen; Mahmoudi Nesheli, Hassan; Shabani, Soraya

2012-01-01

326

Understanding a Widely Misunderstood Statistic: Cronbach's "Alpha"  

ERIC Educational Resources Information Center

It is important to explore score reliability in virtually all studies, because tests are not reliable. The present paper explains the most frequently used reliability estimate, coefficient alpha, so that the coefficient's conceptual underpinnings will be understood. Researchers need to understand score reliability because of the possible impact…

Ritter, Nicola L.

2010-01-01

327

Alpha 97: Basic Education and Institutional Environments.  

ERIC Educational Resources Information Center

This document was published by Alpha, a research program specializing in alternative, experimental approaches to adult basic education. It is an attempt to widen the field and examine the relationship between the micro and macro levels, between the diversity of different practices and the major policy orientations that foster or limit this…

Hautecoeur, Jean-Paul, Ed.

328

E-PERM alpha surface monitor  

SciTech Connect

Innovative Technology Summary Reports are designed to provide potential users with the information they need to quickly determine if a technology would apply to a particular environmental management problem. They are also designed for readers who may recommend that a technology be considered by prospective users. Each report describes a technology, system, or process that has been developed and tested with funding from DOE's Office of Science and Technology (OST). The E-PERM{reg{underscore}sign} Alpha Surface Monitor is an integrating electret ion chamber innovative technology used to measure alpha radiation on surfaces of materials. The technology is best used on surfaces with low contamination levels such as areas with potential for free release, but can also be used in areas with higher levels of contamination. Measurement accuracy and production of the E-PERM {reg{underscore}sign} Alpha Surface Monitor compared favorably with the baseline technology. The innovative technology cost is approximately 28% higher than the baseline with an average unit cost per reading costing %6.04 vs. $4.36; however, the flexibility of the E-PERM{reg{underscore}sign} Alpha Surface Monitor may offer advantages in ALARA, reduction of operator error, waste minimization, and measurement accuracy.

Fricke, V.

1999-12-16

329

Alpha particle diagnostics using impurity pellet injection  

SciTech Connect

We have proposed using impurity injection to measure the energy distribution of the fast confined alpha particles in a reacting plasma. The ablation cloud surrounding the injected pellet is thick enough that an equilibrium fraction F{sub o}{sup {infinity}}(E) of the incident alphas should be neutralized as they pass through the cloud. By observing neutrals created in the large spatial region of the cloud which is expected to be dominated by the helium-like ionization state, e.g., Li{sup +} ions, we can determine the incident alpha distribution dn{sub He}2+/dE from the measured energy distribution of neutral helium atoms. Initial experiments were performed on TEXT in which we compared pellet penetration with our impurity pellet ablation model, and measured the spatial distribution of various ionization states in carbon pellet clouds. Experiments have recently begun on TFTR with the goal of measuring the alpha particle energy distribution during D-T operation in 1993--94. A series of preliminary experiments are planned to test the diagnostic concept. The first experiments will observe neutrals from beam-injected deuterium ions and the high energy {sup 3}He tail produced during ICH minority heating on TFTR interacting with the cloud. We will also monitor by line radiation the charge state distributions in lithium, boron, and carbon clouds.

Fisher, R.K.; McChesney, J.M.; Howald, A.W.; Parks, P.B. (General Atomics, San Diego, CA (United States)); Snipes, J.A.; Terry, J.L.; Marmar, E.S. (Massachusetts Inst. of Tech., Cambridge, MA (United States)); Zweben, S.J.; Medley, S.S. (Princeton Univ., NJ (United States). Plasma Physics Lab.)

1992-05-01

330

[Alpha blocker x beta-blocker].  

PubMed

To control blood pressure for throughout a day, one of antihypertensive drugs will be administered at bedtime. Calcium channel blocker or angiotensin II receptor blocker will be the first line drug for bedtime administration. Alpha-blocker or beta-blocker will be the last choice. PMID:25167757

Ishikawa, Joji; Kario, Kazuomi

2014-08-01

331

Method of making nanocrystalline alpha alumina  

DOEpatents

Method of making selected phases of nanocrystalline ceramic materials. Various methods of controlling the production of nanocrystalline alpha alumina and titanium oxygen phases are described. Control of the gas atmosphere and use of particular oxidation treatments give rise to the ability to control the particular phases provided in the aluminum/oxygen and titanium/oxygen system.

Siegel, Richard W. (Hinsdale, IL); Hahn, Horst (Champaign, IL); Eastman, Jeffrey A. (Woodridge, IL)

1992-01-01

332

Systemic Targeted Alpha Radiotherapy for Cancer  

PubMed Central

Background: The fundamental principles of internal targeted alpha therapy forcancer were established many decades ago.The high linear energy transfer (LET) ofalpha radiation to the targeted cancer cellscauses double strand breaks in DNA. Atthe same time, the short range radiation spares adjacent normal tissues. This targeted approach complements conventional external beam radiotherapy and chemotherapy. Such therapies fail on several fronts, such as lack of control of some primary cancers (e.g. glioblastoma multiforme) and to inhibit the development of lethal metastaticcancer after successful treatment of the primary cancer. Objective: This review charts the developing role of systemic high LET, internalradiation therapy. Method: Targeted alpha therapy is a rapidly advancing experimental therapy thatholds promise to deliver high cytotoxicity to targeted cancer cells. Initially thoughtto be indicated for leukemia and micrometastases, there is now evidence that solidtumors can also be regressed. Results: Alpha therapy may be molecular or physiological in its targeting. Alphaemitting radioisotopes such as Bi-212, Bi-213, At-211 and Ac-225 are used to labelmonoclonal antibodies or proteins that target specific cancer cells. Alternatively, Radium-233 is used for palliative therapy of breast and prostate cancers because of its bone seeking properties. Conclusion: Preclinical studies and clinical trials of alpha therapy are discussedfor leukemia, lymphoma, melanoma, glioblastoma multiforme, bone metastases, ovarian cancer, pancreatic cancer and other cancers. PMID:25505750

Allen, BJ

2013-01-01

333

The Ups and Downs of Alpha Centauri  

NASA Astrophysics Data System (ADS)

The nearby Alpha Centauri triple system has two solar-type stars in a relatively close orbit (20 au separation), and a dim red dwarf companion -- Proxima -- about 10,000 au away, on the Sun-ward side of the group. The heaviest star -- Alpha Cen A -- is a close twin of the Sun. Its slightly less massive companion -- Alpha Cen B -- is a K-type dwarf, and is the closest star thought to host an exoplanet (Earth-sized, but in a much tighter orbit). The close pair has been scrutinized for more than a decade in X-rays by XMM and Chandra, on a semiannual basis since 2003 and 2005, respectively. However, in recent years only Chandra has been able to cleanly separate the pair, which are approaching closest separation on the sky (only a few arcseconds) in their 80-year orbit. For the past 3 years, the HST STIS spectrograph has joined the crowd, also capturing FUV snapshots of the pair every six months. The Alpha Cen stars provide an important complement to long-term studies of the Sun at high energies. The K-star has displayed a clear 8-year cycle in recent years, while the G-star remains mired in a Maunder-like minimum.

Ayres, Thomas R.

2013-07-01

334

A Tutorial on Alpha-channelling  

SciTech Connect

One of the more ambitious uses of intense microwaves in tokamaks or in other magnetic confinement deuterium-tritium (DT) fusion devices would be to divert power from energetic alpha-particles to waves. This so-called "alpha-channelling" would be a large step towards achieving economical fusion power. The intense waves, amplified by the substantial free energy in the alpha-particles, damp on fuel ions, resulting in a hot ion mode, doubling the fusion power of the reactor at the same confined pressure. If the waves damp preferentially on electrons or ions traveling in one direction, current can be driven. This tutorial explains the key concepts and recent advances that lead us to believe in the plausibility of such an effect, at the same time showing how experiments to date give us a measure of confidence in both the simulations themselves, the underlying physical assumptions, and ultimately the reasonableness of the application of these ideas to alpha-channelling in a tokamak reactor.

Fisch, N.J.; Herrmann, M.C.

1998-11-01

335

Intramolecular alpha–Glucosaminidation: Synthesis of Mycothiol  

PubMed Central

A protected cyclitol aglycon was tethered to an (N-arylsulfonyl)glucosamine donor by a methylene linker; the exclusively alpha-selective intramolecular glycosyation reaction was then initiated by electrophilic activation of the thioglycoside donor portion. Further transformations of the glycosylation product to give the M. tuberculosis detoxifier mycothiol and its oxidized congener, the disulfide mycothione, are detailed. PMID:20443569

Ajayi, Kehinde; Thakur, Vinay V.; Lapo, Robert C.; Knapp, Spencer

2010-01-01

336

Production of alpha-amylase by yeast  

SciTech Connect

The enzyme alpha-amylase confers to an organism the enzymatic activity for the degradation of polyglucosides with alpha-1,4 glycosidic bonds such as starch and glycogen which are among the major storage compounds in plants and animals. Most alpha-amylases are single polypeptides of molecular weights around 50,000 dalton. They are generally found in the digestive tract of animals and in germinating seeds. Among the products released upon enzymatic degradation of polyglucosides maltose, a sugar that can be utilized as carbon source by yeast, is a major constituent. A cDNA segment complementary to mouse salivary amylase messenger RNA has been inserted into the yeast expression vector pMA56 behind the promoter of the gene encoding alcohol dehydrogenase I of yeast. Yeast transformants harboring plasmids with the normal orientation of the promoter and the mouse amylase cDNA gene produce amylase and release the enzyme in free form into the culture medium. Approximately 90% of the amylase activity is found in the medium. Yeast strains carrying MAL allele and transformed with a plasmid which directed the synthesis of mouse alpha-amylase were tested on plates containing starch and in batch fermentations using different high molecular weight sugars and oligosaccharides as carbon source. The results of these experiments will be discussed. (Refs. 21).

Thomse, K.K.

1987-01-01

337

Alpha thalassaemia-mental retardation, X linked  

PubMed Central

X-linked alpha thalassaemia mental retardation (ATR-X) syndrome in males is associated with profound developmental delay, facial dysmorphism, genital abnormalities and alpha thalassaemia. Female carriers are usually physically and intellectually normal. So far, 168 patients have been reported. Language is usually very limited. Seizures occur in about one third of the cases. While many patients are affectionate with their caregivers, some exhibit autistic-like behaviour. Patients present with facial hypotonia and a characteristic mouth. Genital abnormalities are observed in 80% of children and range from undescended testes to ambiguous genitalia. Alpha-thalassaemia is not always present. This syndrome is X-linked recessive and results from mutations in the ATRX gene. This gene encodes the widely expressed ATRX protein. ATRX mutations cause diverse changes in the pattern of DNA methylation at heterochromatic loci but it is not yet known whether this is responsible for the clinical phenotype. The diagnosis can be established by detection of alpha thalassaemia, identification of ATRX gene mutations, ATRX protein studies and X-inactivation studies. Genetic counselling can be offered to families. Management is multidisciplinary: young children must be carefully monitored for gastro-oesophageal reflux as it may cause death. A number of individuals with ATR-X are fit and well in their 30s and 40s. PMID:16722615

Gibbons, Richard

2006-01-01

338

Sulfur mobilization in cyanobacteria: the catalytic mechanism of L-cystine C-S lyase (C-DES) from synechocystis.  

PubMed

Sulfur mobilization represents one of the key steps in ubiquitous Fe-S clusters assembly and is performed by a recently characterized set of proteins encompassing cysteine desulfurases, assembly factors, and shuttle proteins. Despite the evolutionary conservation of these proteins, some degree of variability among organisms was observed, which might reflect functional specialization. L-Cyst(e)ine lyase (C-DES), a pyridoxal 5'-phosphatedependent enzyme identified in the cyanobacterium Synechocystis, was reported to use preferentially cystine over cysteine with production of cysteine persulfide, pyruvate, and ammonia. In this study, we demonstrate that C-DES sequences are present in all cyanobacterial genomes and constitute a new family of sulfur-mobilizing enzymes, distinct from cysteine desulfurases. The functional properties of C-DES from Synechocystis sp. PCC 6714 were investigated under pre-steady-state and steady-state conditions. Single wavelength and rapid scanning stopped-flow kinetic data indicate that the internal aldimine reacts with cystine forming an external aldimine that rapidly decays to a transient quinonoid species and stable tautomers of the alpha-aminoacrylate Schiff base. In the presence of cysteine, the transient formation of a dipolar species precedes the selective and stable accumulation of the enolimine tautomer of the external aldimine, with no formation of the alpha-aminoacrylate Schiff base under reducing conditions. Effective sulfur mobilization from cystine might represent a mechanism that allows adaptation of cyanobacteria to different environmental conditions and to light-dark cycles. PMID:17020883

Campanini, Barbara; Schiaretti, Francesca; Abbruzzetti, Stefania; Kessler, Dorothea; Mozzarelli, Andrea

2006-12-15

339

Imaging of Damped Ly-alpha Absorbers  

NASA Astrophysics Data System (ADS)

Intervening H I gas clouds toward QSOs give rise to damped Ly-alpha absorption. Because of the high column density (N(H I)>= 2*E(20) cm(-2) ) these systems have been thought to be galactic disks in some stage of formation. However, because potential optical counterparts have not been identified for most damped Ly-alpha systems, it is possible that some of the absorbing systems could be dwarf irregular galaxies or low surface brightness galaxies, and are thus difficult to image. In any case, the absorbers are expected to have small angular separation from the QSOs, and so high resolution imaging is required to differentiate the absorbers from the QSOs. Because previous studies have not shown any dominant morphological form for the few candidate objects known, our images are obtained with the Hawaii tip-tilt system in order to achieve the best possible morphological classification. By imaging in the NIR and optical bands that bracket the 4000 Angstroms break of these Ly-alpha absorbers, we can more readily select candidate objects by photometrically constraining their redshifts. In our sample of 14 QSOs with abosorbers from 1alpha absorption systems which have no previously optically-identified counterparts, and for some of which we have Keck HIRES spectra. Companion papers in this session present the spectral analysis of two of these QSO's (Roth et al., Bauer et al.) and studies of M81 as a possible local analog of the Ly-alpha absorbers (Kolhatkar et al.)

Jim, K. T. C.; Roth, K. C.

1998-05-01

340

Mechanism of release of active alpha subunit from dimeric alpha beta avian myeloblastosis virus DNA polymerase.  

PubMed Central

Storage of the dimeric (alphabeta) form of avian myeloblastosis virus (AMV) DNA polymerase in glycerol resulted in the release of the smaller alpha subunit, as detected by glycerol gradient sedimentation. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis of enzyme stored in glycerol showed the concomitant appearance of several polypeptides and a lowering in the level of both beta and alpha components. This reduction appears to be the result of cleavages introduced by traces of hydrolytic activity present in glycerol samples. An enhancement of alpha subunit released, as detected by activity profile, was also achieved upon direct but limited exposure of purified avian myeloblastosis virus DNA polymerase to carboxymethyl-cellulose-bound trypsin matrix. Electrophoretic analysis of digested enzyme revealed a progressive fragmentation, with simultaneous increase in the alpha subunit and decrease in the beta subunit. PMID:58080

Papas, T S; Marciani, D J; Samuel, K; Chirikjian, J G

1976-01-01

341

40 CFR 721.10214 - Poly(oxyalkylenediyl),.alpha.-substituted carbomonocycle-.omega.-substituted carbomonocycle...  

Code of Federal Regulations, 2011 CFR

... false Poly(oxyalkylenediyl),.alpha.-substituted carbomonocycle-.omega...10214 Poly(oxyalkylenediyl),.alpha.-substituted carbomonocycle-.omega...generically as poly(oxyalkylenediyl),.alpha.-substituted...

2011-07-01

342

Erweiterung des Fermat Problems Matthias Monzel, Oksana Vogelsang, Patrick Hans  

E-print Network

Erweiterung des Fermat Problems Matthias Monzel, Oksana Vogelsang, Patrick Hans Sommersemester 2013 Matthias Monzel, Oksana Vogelsang, Patrick Hans Erweiterung des Fermat Problems #12;Inhaltsverzeichnis 1 Beweis zum Fermat-Punkt 2 Erweiterung des Problems auf vier Standorte 3 Erweiterung des Problems auf drei

Krumke, Sven O.

343

RECHERCHES EXPRIMENTALES SUR LA DURE DE PASSAGE DES SPERMATOZODES  

E-print Network

pertes d'ADN au cours des extractions : - variations dans la teneur en ADN en fonction du nombre des lavages avec la solution de KREI3S-lIENSELEIT-RINGER, - variations dans la teneur en ADN des autres : - contamination par le plasma séminal des phospholipides,- contamination de l'ADN. 2. Dosage du

Boyer, Edmond

344

VOLUTION DES FERRITES DOUX POUR TLCOMMUNICATIONS ET TLVISION  

E-print Network

the 15 last years : improvement of composition, magnetic circuits, technologies, a. s. o. Results années : améliorations des compositions des matériaux, des circuits magnétiques, des technologies de. 2014 In spite of the fact that the soft ferrites are old materials (their development has been made

Boyer, Edmond

345

Caractristiques spectrales de pigesjaunes utiliss pour la capture des aphides  

E-print Network

Caractéristiques spectrales de piègesjaunes utilisés pour la capture des aphides Charles BALDY Jean'atterrissage des aphides. La répartition spectrale et Transmittance, l'intensité des réflectances à des longueurs d Spectral characteristics of yellow water pans used for aphid trapping Visible spectrophotometry

Paris-Sud XI, Université de

346

enNouvelle-Caldonie La dgradation des habitats  

E-print Network

recouvrement des fonds marins de particules fines provenant du décapage des mines, provoquant la mort de étude a pu identifier 200 plantes exotiques envahissantes parmi lesquelles 100 présentent une menace ailleurs pour être invasives. Surpâturage, consommation des jeunes pousses d'arbres, des graines, arrêt de

347

Une etude sur la traduction des -termes dans le -calcul  

E-print Network

#25; et #21; Une #19;etude sur la traduction des #21;-termes dans le #25;-calcul Damiano Mazza #3;-calcul, un formalisme introduit #18;a la #12;n des ann#19;ees '80 pour la mod#19;elisation des syst#18;emes mobiles, et le #21;-calcul, l'un des mod#18;eles de calcul les plus connus et utilis#19;es en

Mazza, Damiano

348

Lipopolysaccharide-induced cytokine cascade and lethality in LT alpha/TNF alpha-deficient mice.  

PubMed Central

BACKGROUND: Tumor necrosis factor alpha (TNF-alpha) is often considered the main proinflammatory cytokine induced by lipopolysaccharide (LPS) and consequently the critical mediator of the lethality associated with septic shock. MATERIALS AND METHODS: We used mice carrying a deletion of both the lymphotoxin alpha (LT-alpha) and TNF-alpha genes to assess the role of TNF in the cytokine cascade and lethality induced by LPS. RESULTS: Initial production of IL-1 alpha, IL-1 beta, IL-6, and IL-10 is comparable in wild-type and mutant mice. However, at later times, expression of IL-1 alpha, IL-1 beta, and IL-10 is prolonged, whereas that of IL-6 decreases in mutant mice. Expression of IFN-gamma is almost completely abrogated in mutants, which is in agreement with a more significant alteration of the late phase of the cytokine cascade. We measured similar LD50 (600 micrograms) for the intravenous injection of LPS in mice of the three genotypes (+/+, +/-, -/-), demonstrating that the absence of TNF does not confer long-term protection from lethality. However, death occurred much more slowly in mutant mice, who were protected more efficiently from death by CNI 1493, an inhibitor of proinflammatory cytokine production, than were wild-type mice. DISCUSSION: Thus, while TNF-alpha is not required for the induction of these cytokines by LPS, it modulates the kinetics of their expression. The lethality studies simultaneously confirm a role for TNF as a mediator of early lethality and establish that, in the absence of these cytokines, other mediators take over, resulting in the absence of long-term protection from LPS toxicity. Images FIG. 1 FIG. 2 PMID:9440119

Amiot, F.; Fitting, C.; Tracey, K. J.; Cavaillon, J. M.; Dautry, F.

1997-01-01

349

An assay for intermolecular exchange of alpha crystallin  

NASA Technical Reports Server (NTRS)

An affinity column of alpha crystallin linked to cyanogen bromide-activated Sepharose was developed to study the exchange of alpha subunits. Alpha crystallin bound to the Sepharose-alpha complex was dissociated with 8 mol/l urea, followed by quantitation using high-performance reverse-phase liquid chromatography. The time course of binding at 37 degrees C showed a hyperbolic binding pattern reaching equilibrium between 6-18 hr. Under these conditions, binding of beta and gamma crystallins to the same matrix was less than 10% of the alpha values, as was binding of alpha to glycine-coupled Sepharose. This assay was used to demonstrate changes in the subunit exchange of alpha crystallins present in high molecular weight versus lower molecular weight aggregates of the human lens. These results show that this binding procedure was a specific reproducible assay that might be used to study intermolecular interactions of the alpha crystallins.

Gopalakrishnan, S.; Takemoto, L.; Spooner, B. S. (Principal Investigator)

1992-01-01

350

Study of alpha background in a dark matter detector  

E-print Network

Alpha background, specifically from radon and its progeny in the uranium and thorium chains, has been a major issue in dark matter detectors. This work focuses on alpha background presence in the DMTPC experiment by examining ...

Yegoryan, Hayk

2010-01-01

351

29 CFR 1926.1104 - alpha-Naphthylamine.  

Code of Federal Regulations, 2011 CFR

29 Labor 8 2011-07-01 2011-07-01 false alpha-Naphthylamine. 1926.1104 Section 1926.1104 Labor...CONSTRUCTION Toxic and Hazardous Substances § 1926.1104 alpha-Naphthylamine. Note: The requirements applicable...

2011-07-01

352

29 CFR 1915.1004 - alpha-Naphthylamine.  

Code of Federal Regulations, 2011 CFR

29 Labor 7 2011-07-01 2011-07-01 false alpha-Naphthylamine. 1915.1004 Section 1915.1004 Labor...EMPLOYMENT Toxic and Hazardous Substances § 1915.1004 alpha-Naphthylamine. Note: The requirements applicable...

2011-07-01

353

29 CFR 1926.1104 - alpha-Naphthylamine.  

Code of Federal Regulations, 2010 CFR

29 Labor 8 2010-07-01 2010-07-01 false alpha-Naphthylamine. 1926.1104 Section 1926.1104 Labor...CONSTRUCTION Toxic and Hazardous Substances § 1926.1104 alpha-Naphthylamine. Note: The requirements applicable...

2010-07-01

354

29 CFR 1915.1004 - alpha-Naphthylamine.  

Code of Federal Regulations, 2010 CFR

29 Labor 7 2010-07-01 2010-07-01 false alpha-Naphthylamine. 1915.1004 Section 1915.1004 Labor...EMPLOYMENT Toxic and Hazardous Substances § 1915.1004 alpha-Naphthylamine. Note: The requirements applicable...

2010-07-01

355

Antibody-mediated reduction of .alpha.-ketoamides  

DOEpatents

Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an .alpha.-ketoamide to the corresponding .alpha.-hydroxyamide in the presence of an appropriate reducing agent.

Schultz, Peter G. (Oakland, CA); Gallop, Mark A. (East Palo Alto, CA)

1998-01-01

356

Genetics Home Reference: Alpha-methylacyl-CoA racemase deficiency  

MedlinePLUS

... PubMed Recent literature OMIM Genetic disorder catalog Conditions > Alpha-methylacyl-CoA racemase deficiency (often shortened to AMACR ... definitions Reviewed December 2013 What is AMACR deficiency? Alpha-methylacyl-CoA racemase (AMACR) deficiency is a disorder ...

357

Antibody-mediated reduction of {alpha}-ketoamides  

DOEpatents

Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an {alpha}-ketoamide to the corresponding {alpha}-hydroxyamide in the presence of an appropriate reducing agent.

Schultz, P.G.; Gallop, M.A.

1998-06-09

358

Linopirdine blocks alpha9alpha10-containing nicotinic cholinergic receptors of cochlear hair cells.  

PubMed

Studies of the electrophysiological response to acetylcholine (ACh) in mammalian outer hair cells (OHCs) are hindered by the presence of a large potassium current, I(K,n), most likely mediated by channels containing the KCNQ4 subunit. Since I(K,n) can be blocked by linopirdine, cholinergic effects might be better revealed in the presence of this compound. The aim of the present work was to study the effects of linopirdine on the ACh-evoked responses through alpha9alpha10-containing native and recombinant nicotinic cholinergic receptors. Responses to ACh were blocked by linopirdine in both OHCs and inner hair cells (IHCs) of rats at postnatal days 21-27 (OHCs) and 9-11 (IHCs). In addition, linopirdine blocked responses of recombinant alpha9alpha10 nicotinic cholinergic receptors (nAChRs) in a concentration-dependent manner with an IC(50) of 5.2 microM. Block by linopirdine was readily reversible, voltage independent, and surmountable at high concentrations of ACh, thus suggestive of a competitive type of interaction with the receptor. The present results contribute to the pharmacological characterization of alpha9alpha10-containing nicotinic receptors and indicate that linopirdine should be used with caution when analyzing the cholinergic sensitivity of cochlear hair cells. PMID:15492885

Gomez-Casati, María E; Katz, Eleonora; Glowatzki, Elisabeth; Lioudyno, María I; Fuchs, Paul; Elgoyhen, A Belén

2004-09-01

359

Lyman-alpha emission from the damped Lyman-alpha system toward H0836 + 113  

NASA Astrophysics Data System (ADS)

This study presents results of a comprehensive search for Ly-alpha emission from the 2.466-redshift damped Ly-alpha system toward the QSO H0836 + 113. Deep CCD images of the field surrounding the QSO were acquired with a narrow-band filter tuned to the wavelength centroid of the 2.466-redshift damped Ly-alpha line. Two superposed objects, one extended and the other compact, were detected within 4 arcsec of the QSO. Evidence is presented indicating that the extended object, seen only in the narrow-band frames, was detected in the light of Ly-alpha line radiation emitted by the damped system, while the compact object, seen with the broadband filters and in the narrow-band frames acquired with superior seeing, was detected in the light of the continuum radiation emitted by a foreground Mg II galaxy with a redshift of 0.79. Accurate spectra of the QSO were also obtained in order to observe the spatially unresolved Ly-alpha emission feature reported to exist at the bottom of the damped Ly-alpha absorption trough.

Wolfe, A. M.; Lanzetta, K. M.; Turnshek, D. A.; Oke, J. B.

1992-01-01

360

Processing of tumour necrosis factor-alpha precursor by metalloproteinases  

Microsoft Academic Search

TUMOUR necrosis factor-alpha (TNF-alpha) is a potent pro-inflammatory and immunomodulatory cytokine implicated in inflammatory conditions such as rheumatoid arthritis, Crohn's disease, multiple sclerosis and the cachexia associated with cancer or human immunodeficiency virus infection1. TNF-alpha is initially expressed as a 233-amino-acid membrane-anchored precursor which is proteolytically processed to yield the mature, 157-amino-acid cytokine2. The processing enzyme(s) which cleave TNF-alpha are

A. J. H. Gearing; P. Beckett; M. Christodoulou; M. Churchill; J. Clements; A. H. Davidson; A. H. Drummond; W. A. Galloway; R. Gilbert; J. L. Gordon; T. M. Leber; M. Mangan; K. Miller; P. Nayee; K. Owen; S. Patel; W. Thomas; G. Wells; L. M. Wood; K. Woolley

1994-01-01

361

Spendenzusage im Rahmen des Deutschlandstipendienprogramms I. Die Firma/Organisation/Privatperson  

E-print Network

1 Spendenzusage im Rahmen des Deutschlandstipendienprogramms I. Die Firma/Organisation (Kassenzeichen) und Bezeichnung des Stipendiengebers V. Kontaktdaten der Spenderin/des Spenders Firma/Organisation

Greifswald, Ernst-Moritz-Arndt-Universität

362

Hematotoxic effects of 3,5-dinitro-4-chloro-alpha,alpha,alpha-trifluorotoluene, a water contaminant  

SciTech Connect

Three short-term studies of 7, 14, and 21 days, respectively, were made to investigate the nature of the anemia induced in rats by 3,5-dinitro-4-chloro-alpha,alpha,alpha-trifluorotoluene (DNCTT). This compound is an intermediate in the synthesis of dinitroaniline herbicides and was detected as a contaminant of a water-bearing stratum in northern Italy. DNCTT was mixed in a powdered rodent diet at a level of 2000 ppm and administered to Wistar-derived rats. DNCTT was shown to produce a hemolytic anemia of rapid onset; packed cell volume and hemoglobin concentration were decreased at all three treatment periods. Methemoglobin and reticulocyte count were increased in all the treated groups. The relative organ weights of the spleen and the liver were increased compared to those of the control groups. Spleen enlargement was also evident at the macroscopic examination, whereas the liver appearance was normal. Pearl's Prussian blue staining performed on the spleen and liver was highly positive in the spleen of treated rats, but no iron deposition was detected in the liver of treated rats.

Guastadisegni, C.; Hall, D.; Macri, A.

1986-10-01

363

Alpha thalassemia major—new mutations, intrauterine management, and outcomes  

Microsoft Academic Search

Alpha thalassemia disorders are a group of hereditary anemias caused by absent or decreased produc- tion of the alpha chain of hemoglobin. Hemoglobin Bart's hydrops fetalis is usually a fatal in-utero disease caused by absence of the alpha genes. However, the molecular and genotypic expression of hemoglobin Bart's varies and increasing numbers of births are being reported. Population screening and

Elliott P. Vichinsky

364

Alpha Globulin Injections and Decreased Gamma Globulin Production in Chickens  

Microsoft Academic Search

Electrophoretic analysis shows a strong similarity in the blood serums of chickens subjected to egg parabiosis and of chickens repeatedly injected with fraction IV (alpha globulins). In both instances there is an evident rise in the albumin-plus alpha 1 titer and an evident decrease in the gamma globulin levels. These findings suggest that the injection of alpha globulins has the

Benjamin B. Kamrin

1966-01-01

365

Alpha-particle-induced soft errors in dynamic memories  

Microsoft Academic Search

A new physical soft error mechanism in dynamic RAM's and CCD's is the upset of stored data by the passage of alpha particles through the memory array area. The alpha particles are emitted by the radioactive decay of uranium and thorium which are present in parts-per-million levels in packaging materials. When an alpha particle penetrates the die surface, it can

T. C. May; M. H. Woods

1979-01-01

366

Alpha and the Gay Issue: A Lesson in Homophobia?  

ERIC Educational Resources Information Center

The Alpha course is possibly the most widespread and best-known evangelizing initiative of recent times. Billing itself as an introduction into "basic Christianity", Alpha is a programme that has been adopted worldwide by tens of thousands of churches. This paper overviews Alpha's attitude towards one of the most controversial debates in the…

Hunt, Stephen John

2005-01-01

367

Asymptotically Distribution-Free (ADF) Interval Estimation of Coefficient Alpha  

ERIC Educational Resources Information Center

The point estimate of sample coefficient alpha may provide a misleading impression of the reliability of the test score. Because sample coefficient alpha is consistently biased downward, it is more likely to yield a misleading impression of poor reliability. The magnitude of the bias is greatest precisely when the variability of sample alpha is…

Maydeu-Olivares, Alberto; Coffman, Donna L.; Hartmann, Wolfgang M.

2007-01-01

368

Article de synthse Stockage des spermatozodes dans l'oviducte  

E-print Network

Article de synthèse Stockage des spermatozoïdes dans l'oviducte chez les oiseaux : approche la bibliographie consacrée aux aspects anatomique, his- tologique et fonctionnel du stockage des qui contrôle l'entrée et/ou le stockage des spermatozoïdes dans les glandes utéro-vaginales est de na

Paris-Sud XI, Université de

369

OzDES: 100 Nights of AAT Spectroscopy on DES Sources  

NASA Astrophysics Data System (ADS)

OzDES is a 5 year, 100 night spectroscopic program on AAT using 2dF/AAOmega that commenced in September 2013. A collaboration between the Dark Energy Survey (DES) and members of the Australian astronomical community, OzDES will efficiently obtain spectra for a wide variety of DES science programs thanks to the near perfect overlap between the Dark Energy Camera and 2dF fields of view. The driver for the program is the DES Supernova Survey, as redshifts for supernova host galaxies down to 24 can be measured through repeated integrations over the duration of the survey. In addition to supernova host galaxies and many live supernovae, OzDES will perform a study of reverberation mapping of AGN, target strong lenses, and obtain redshifts for photo-z calibration.

D'Andrea, Christopher; OzDES

2014-01-01

370

C-Terminal truncation affects subunit exchange of human alphaA-crystallin with alphaB-crystallin.  

PubMed

In human lenses, C-terminal cleavage of alphaA-crystallin at residues 172,168, and 162 have been reported. The effect of C-terminal truncation of alphaA-crystallin on subunit exchange and heterooligomer formation with alphaB-crystallin and homooligomer formation with native alphaA-crystallin is not known. We have conducted fluorescence resonance energy transfer studies which have shown that the rates of subunit exchange of alphaA(1-172 )and alphaA(1-168 )with alphaB-wt were two-fold lower than for alphaA-wt interacting with alphaB-wt. The subunit exchange rate between alphaA(1-162) and alphaB-wt was six-fold lower. These data suggest that cleavage of the C-terminal residues could significantly affect heterooligomerization. On the other hand, the subunit exchange rates between alphaA-wt and the truncated alphaA-crystallins were either unchanged or only slightly decreased, which suggest that homooligomerization may not be significantly influenced by C-terminal truncation. The main conclusion from this study is that cleavage of C-terminal residues of alphaA-crystallin including the nine residues of the flexible tail is expected to significantly affect the formation of heteroaggregates. Reconstitution experiments showed that the presence of an intact C-terminus is essential for the formation of fully integrated heteroaggregates with equal proportion of alphaA and alphaB subunits. PMID:17909943

Kallur, Latha S; Aziz, Atya; Abraham, Edathara C

2008-01-01

371

A pyridazine series of alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.  

PubMed

The development of a series of GABA(A) alpha2/alpha3 subtype selective pyridazine based benzodiazepine site agonists as anxiolytic agents with reduced sedative/ataxic potential is described, including the discovery of 16, a remarkably alpha3-selective compound ideal for in vivo study. These ligands are antagonists at the alpha1 subtype, with good CNS penetration and receptor occupancy, and excellent oral bioavailability. PMID:16610803

Lewis, Richard T; Blackaby, Wesley P; Blackburn, Timothy; Jennings, Andrew S R; Pike, Andrew; Wilson, Rowan A; Hallett, David J; Cook, Susan M; Ferris, Pushpinder; Marshall, George R; Reynolds, David S; Sheppard, Wayne F A; Smith, Alison J; Sohal, Bindi; Stanley, Joanna; Tye, Spencer J; Wafford, Keith A; Atack, John R

2006-04-20

372

Project Longshot: A mission to Alpha Centauri  

NASA Technical Reports Server (NTRS)

Project Longshot, an exercise in the Advanced Design Program for Space, had as its destination Alpha Centauri, the closest star system to our own solar system. Alpha Centauri, a trinary star system, is 4.34 light years from earth. Although Project Longshot is impossible based on existing technologies, areas that require further investigation in order to make this feat possible are identified. Three areas where advances in technology are needed are propulsion, data processing for autonomous command and control functions, and reliability. Propulsion, possibly by antimatter annihilation; navigation and navigation aids; reliable hardware and instruments; artificial intelligence to eliminate the need for command telemetry; laser communication; and a reliable, compact, and lightweight power system that converts energy efficiently and reliably present major challenges. Project Longshot promises exciting advances in science and technology and new information concerning the universe.

West, Curtis; Chamberlain, Sally; Pagan, Neftali; Stevens, Robert

1989-01-01

373

Automatically processed alpha-track radon monitor  

DOEpatents

An automatically processed alpha-track radon monitor is provided which includes a housing having an aperture allowing radon entry, and a filter that excludes the entry of radon daughters into the housing. A flexible track registration material is located within the housing that records alpha-particle emissions from the decay of radon and radon daughters inside the housing. The flexible track registration material is capable of being spliced such that the registration material from a plurality of monitors can be spliced into a single strip to facilitate automatic processing of the registration material from the plurality of monitors. A process for the automatic counting of radon registered by a radon monitor is also provided.

Langner, G.H. Jr.

1993-01-12

374

Automatically processed alpha-track radon monitor  

DOEpatents

An automatically processed alpha-track radon monitor is provided which includes a housing having an aperture allowing radon entry, and a filter that excludes the entry of radon daughters into the housing. A flexible track registration material is located within the housing that records alpha-particle emissions from the decay of radon and radon daughters inside the housing. The flexible track registration material is capable of being spliced such that the registration material from a plurality of monitors can be spliced into a single strip to facilitate automatic processing of the registration material from the plurality of monitors. A process for the automatic counting of radon registered by a radon monitor is also provided.

Langner, Jr., G. Harold (Mack, CO)

1993-01-01

375

Optical conductivity of alpha-Mn  

NASA Technical Reports Server (NTRS)

The optical constants were measured at room temperature in the photon-energy range 0.6 to 6.5 eV on evaporated thin films. Evaporation conditions were chosen that gave the alpha-Mn crystal structure with reasonably large grains. The optical conductivity was separated into intraband and interband contributions by fitting to the Drude formula at low energies. The results are anomalous in comparison to other 3d transition metals. The free-electron lifetime is exceptionally sort (in agreement with the large dc resistivity of Mn), and the interband transitions seem unusually weak at the lower energies. Possible explanations related to the complicated crystal structure of alpha-Mn are discussed.

Scoles, K. J.; Christy, R. W.

1982-01-01

376

Lyman alpha emissions in the outer heliosphere  

NASA Technical Reports Server (NTRS)

Since 1993, the Ultraviolet Spectrometers aboard both Voyager 1 and 2, were used to study the Ly-alpha glow pattern backscattered by neutral hydrogen atoms at great distance from the sun. When compared to a radiative transfer calculation for an unperturbed interstellar hydrogen flow into the solar system, the data present an excess of intensity seen in the direction of the incoming interstellar wind. An absolute estimate of this Lyman alpha intensity yields 10 to 15 Rayleighs for each spacecraft. We discuss the possibility that this excess is caused by a gradient of hydrogen at large distance from the Sun due to the filtration of interstellar hydrogen when crossing the heliopause. Comparisons with results from the Baranov-Malama model of neutral-plasma coupling at the heliopause are presented. The data yield a range of possible values for the hydrogen gradient which may be used to infer the location of the heliopause.

Quemerais, E.; Lallement, R.; Bertaux, J. L.; Sandel, B. R.

1995-01-01

377

Are Proxima and Alpha Centauri Gravitationally Bound?  

E-print Network

Using the most recent kinematic and radial velocity data in the literature, we calculate the binding energy of Proxima Centauri relative to the center of mass of the Alpha Centauri system. When we adopt the centroids of the observed data, we find that the three stars constitute a bound system, albeit with a semi-major axis that is on order the same size as Alpha Centauri AB's Hill radius in the galactic potential. We carry out a Monte Carlo simulation under the assumption that the errors in the observed quantities are uncorrelated. In this simulation, 44% of the trial systems are bound, and systems on the 1-3 sigma tail of the radial velocity distribution can have Proxima currently located near the apastron position of its orbit. Our analysis shows that a further, very significant improvement in the characterization of the system can be gained by obtaining a more accurate measurement of the radial velocity of Proxima Centauri.

Jeremy G. Wertheimer; Gregory Laughlin

2006-07-17

378

Matrise et usage des TIC : la situation des enseignants en Belgique francophone  

E-print Network

1 Maîtrise et usage des TIC : la situation des enseignants en Belgique francophone Henry Julie discours européen concernant la maîtrise des TIC par les enseignants, les auteurs pointent du doigt les complémentaires et présentent la seule certification TIC existant à l'heure d'écrire ce texte : form@TICEF. La

Paris-Sud XI, Université de

379

SUR LA DISTRIBUTION DES INTERVALLES D'MISSION DES PARTICULES 03B1 DU POLONIUM  

E-print Network

SUR LA DISTRIBUTION DES INTERVALLES D'�MISSION DES PARTICULES 03B1 DU POLONIUM Par Mme CURIE. J'ai. publié, en 1911, quelques résultats relatifs à la numération des par- ticules a du polonium et à la loi'un long travail sur le polonium entrepris en collaboration avec M. Debierne. Ce travail avait pour but la

Paris-Sud XI, Université de

380

Contribution l'analyse des dterminants du comportement d'exercice des porteurs de stock options  

E-print Network

1 Contribution à l'analyse des déterminants du comportement d'exercice des porteurs de stock déterminants du comportement des salariés quant à l'exercice de leurs stock options, en mettant en lumière de'exercice de stock options dans 12 multinationales cotées aux Etats Unis. Nos résultats sont cohérents avec les

Paris-Sud XI, Université de

381

CONTRIBUTION A L'TUDE ANTIGNIQUE DES VIRUS INFLUENZA DES ANIMAUX  

E-print Network

CONTRIBUTION A L'�TUDE ANTIG�NIQUE DES VIRUS INFLUENZA DES ANIMAUX I. - NEURAMINIDASE DES VIRUS/Duck/Ukraine/63 (Hav7 Neq2) has the same neuraminidase as the equine virus A/equi !/Miami/63 (Heq2 Neq2) ; the A/Chicken Germany « N »/49 virus has the same neuraminidase as the equine virus A/equi i/Prague/!6. A comparative

Paris-Sud XI, Université de

382

SPARATION DES SPECTRES DES DIVERS ORDRES DU CADMIUM par M. FLIX ESCLANGON,  

E-print Network

S�PARATION DES SPECTRES DES DIVERS ORDRES DU CADMIUM par M. F�LIX ESCLANGON, Ecole Normale Supérieure, Paris. Sommaire. 2014 Nous avons appliqué au cadmium la méthode de séparation des raies dues aux parcourt quelques spires entourant un tube à cadmium et l'illumine si la température est convenable. Le

Paris-Sud XI, Université de

383

Dveloppement des techniques de surveillance des mouvements de terrain : cas de la carrire souterraine de Grozon.  

E-print Network

, notamment lorsque ce dernier est situé dans des zones présentant des dangers importants vis-à-vis de la développer au sein des anciens vides et se propager vers la surface. Les principales causes de désordres produire en surface. Le problème le plus délicat se pose évidemment en terme de gestion du bâti existant

Paris-Sud XI, Université de

384

Comptes Rendus des JNC 17 -Poitiers 2011 Trois approches cohrentes pour modliser la multifissuration des composites  

E-print Network

multifissuration des composites 1D Three consistent approaches of the multiple cracking process in 1D composites �.lantuejoul@mines-paristech.fr Résumé Il existe de nombreux modèles pour décrire la fissuration des composites 1D, avec, pour la plupart classer en trois approches : la première approche (CL) discrétise le composite, et tire aléatoirement des

Paris-Sud XI, Université de

385

The vinculin/sarcomeric-alpha-actinin/alpha-actin nexus in cultured cardiac myocytes  

PubMed Central

Experiments are described supporting the proposition that the assembly of stress fibers in non-muscle cells and the assembly of myofibrils in cardiac cells share conserved mechanisms. Double staining with a battery of labeled antibodies against membrane-associated proteins, myofibrillar proteins, and stress fiber proteins reveals the following: (a) dissociated, cultured cardiac myocytes reconstitute intercalated discs consisting of adherens junctions (AJs) and desmosomes at sites of cell-cell contact and sub-sarcolemmal adhesion plaques (SAPs) at sites of cell-substrate contact; (b) each AJ or SAP associates proximally with a striated myofibril, and conversely every striated myofibril is capped at either end by an AJ or a SAP; (C) the invariant association between a given myofibril and its SAP is especially prominent at the earliest stages of myofibrillogenesis; nascent myofibrils are capped by oppositely oriented SAPs; (d) the insertion of nascent myofibrils into AJs or into SAPs invariably involves vinculin, alpha-actin, and sarcomeric alpha-actinin (s-alpha-actinin); (e) AJs are positive for A- CAM but negative for talin and integrin; SAPs lack A-CAM but are positive for talin and integrin; (f) in cardiac cells all alpha-actinin- containing structures invariably are positive for the sarcomeric isoform, alpha-actin and related sarcomeric proteins; they lack non-s- alpha-actinin, gamma-actin, and caldesmon; (g) in fibroblasts all alpha- actinin-containing structures are positive for the non-sarcomeric isoform, gamma-actin, and related non-sarcomeric proteins, including caldesmon; and (h) myocytes differ from all other types of adherent cultured cells in that they do not assemble authentic stress fibers; instead they assemble stress fiber-like structures of linearly aligned I-Z-I-like complexes consisting exclusively of sarcomeric proteins. PMID:1577864

1992-01-01

386

Five Axioms of Alpha-Conversion  

Microsoft Academic Search

We present v e axioms of name-carrying lambda-terms iden- tied up to alpha-conversion|that is, up to renaming of bound variables. We assume constructors for constants, variables, application and lambda- abstraction. Other constants represent a function Fv that returns the set of free variables in a term and a function that substitutes a term for a variable free in another term.

Andrew D. Gordon; Thomas F. Melham

1996-01-01

387

Hydrogen in alpha -iron: Stress and diffusion  

Microsoft Academic Search

First-principles density-functional theory has been used to investigate equilibrium geometries, total energies, and diffusion barriers for H as an interstitial impurity absorbed in alpha-Fe . Internal strains\\/stresses upon hydrogen absorption are a crucial factor to understand preferred absorption sites and diffusion. For high concentrations, H absorbs near the octahedral site favoring a large tetragonal distortion of the bcc lattice. For

J. Sanchez; J. Fullea; C. Andrade; P. L. de Andres

2008-01-01

388

5Alpha Reductase Inhibitors in Prostate Cancer  

Microsoft Academic Search

\\u000a Androgenic effects in prostate cancer cells depend on the synthesis and metabolism of hormones and the presence of androgen\\u000a receptor. 5-alpha reductase isoenzymes I and II differ in chromosomal localization, pH optimum, enzyme kinetics, and expression\\u000a in benign and malignant prostate tissue. In prostate cancer tissues, there is an increased expression of the isoenzyme type\\u000a I. The possibilities for pharmacological

Zoran Culig

389

Rh(II)-Catalyzed Reaction Of Some alpha',alpha'- and beta'-Branched-O-Alkyl alpha-(Alkoxycarbonyl)-alpha-diazoacetates.  

PubMed

alpha',alpha'- and beta'- Branched-O-alkyl alpha-(alkoxycarbonyl)-alpha-diazoacetates 1a,b and 2a,b were prepared. The regio- and chemoselectivities in the Rh(II)-catalyzed reaction of these compounds were studied. The model systems 1a,b showed that the reactivity of the ester-substituted Rh(II) carbenoid is responsive to the nature of the Rh(II) catalyst; rhodium(II) acetamide favored insertion into the tertiary C-H bond and rhodium(II) perfluorobutyrate favored insertion into the secondary C-H bond. We also found that the nature of the O-alkyl group in the ester moiety had no influence on the reactivity of the Rh(II) carbenoid. In more complex systems such as compounds 2, it was found that rhodium(II) acetate promoted insertion into tertiary C-H bonds. Intramolecular cyclopropanation, to give 3-oxabicyclo[5.1.0]octane and 3-oxabicyclo[6.1.0]nonane products, was found to be competitive with tertiary C-H insertion; it is favored when rhodium(II) perfluorobutyrate was used as the catalyst. The Rh(II)-catalyzed reaction of 3 ("carbon" analog of 2a) resulted mainly in the cyclopentanone derivative, and no cyclopropanation product was detected. This result indicates that the ester oxygen in compounds of type 2 plays an important role in influencing the regio- and chemoselectivities of their reaction. Overall the results indicate that for compounds of a particular type of structure the regio- and chemoselectivities can be controlled via the judicious choice of the Rh(II) catalyst. PMID:11671719

Wee, Andrew G. H.; Yu, Qing

1997-05-16

390

Lyman Alpha Emitters in gravitational lensed fields  

NASA Astrophysics Data System (ADS)

We study the luminosity function of Lyman Alpha Emitters (LAEs) at redshifts between z~6.5 in strong gravitational lensed (GL) fields by clusters of galaxies, using OSIRIS tunable filters (TFs) at the GTC. OSIRIS TFs enhance the emission line contrast, together with the total flux magnification produced by the lens, will be used to detect faint LAEs and to extend the low luminosity queue of the Luminosity Function (LF) of LAEs.

De Leo, M. A.; de Diego, J. A.; Verdugo, T.; Bongiovanni, A.; Cepa, J.; González-Serrano, J. I.

2013-05-01

391

Alpha decay of neutron deficient astatine isotopes  

Microsoft Academic Search

Isotopes of astatine lighter than mass 205 were studied at the Heavy Ion Linear Accelerator by bombardment of 185Re and 187Re with 20Ne, using Si (Au) surface barrier detectors in on-line measurements. Mass number assignments of astatine 201 through 196 are based on excitation functions and on genetic relationships with polonium isotopes. Accurate alpha energies are reported for 204At through

William Treytl; Kalevi Valli

1967-01-01

392

Fourth High Alpha Conference, volume 1  

NASA Technical Reports Server (NTRS)

The goal of the Fourth High Alpha Conference was to focus on the flight validation of high angle-of-attack technologies and provide an in-depth review of the latest high angle-of-attack activities. Areas that were covered include: high angle-of-attack aerodynamics, propulsion and inlet dynamics, thrust vectoring, control laws and handling qualities, tactical utility, and forebody controls.

1994-01-01

393

Optimisation des schemas d'ouverture des secteurs de contr^ole aerien par methodes classiques et algorithmes genetiques  

E-print Network

Optimisation des sch´emas d'ouverture des secteurs de contr^ole a´erien par m´ethodes classiques et plusieurs algorithmes construisant des configurations optimales de sec- teurs de contr^ole a´erien, en tenant compte du tra- fic pr´evu, des capacit´es des secteurs, et du nombre de positions de contr^ole

Paris-Sud XI, Université de

394

Fasting induces basolateral uptake transporters of the SLC family in the liver via HNF4alpha and PGC1alpha.  

PubMed

Fasting induces numerous adaptive changes in metabolism by several central signaling pathways, the most important represented by the HNF4alpha/PGC-1alpha-pathway. Because HNF4alpha has been identified as central regulator of basolateral bile acid transporters and a previous study reports increased basolateral bile acid uptake into the liver during fasting, we hypothesized that HNF4alpha is involved in fasting-induced bile acid uptake via upregulation of basolateral bile acid transporters. In rats, mRNA of Ntcp, Oatp1, and Oatp2 were significantly increased after 48 h of fasting. Protein expression as determined by Western blot showed significant increases for all three transporters 72 h after the onset of fasting. Whereas binding activity of HNF1alpha in electrophoretic mobility shift assays remained unchanged, HNF4alpha binding activity to the Ntcp promoter was increased significantly. In line with this result, we found significantly increased mRNA expression of HNF4alpha and PGC-1alpha. Functional studies in HepG2 cells revealed an increased endogenous NTCP mRNA expression upon cotransfection with either HNF4alpha, PGC-1alpha, or a combination of both. We conclude that upregulation of the basolateral bile acid transporters Ntcp, Oatp1, and Oatp2 in fasted rats is mediated via the HNF4alpha/PGC-1alpha pathway. PMID:17640976

Dietrich, Christoph G; Martin, Ina V; Porn, Anne C; Voigt, Sebastian; Gartung, Carsten; Trautwein, Christian; Geier, Andreas

2007-09-01

395

Use of infinitely thick source alpha particle pulse height distributions in the determination of individual specific alpha activities  

Microsoft Academic Search

A method is presented in which material containing a complex mixture of alpha emitting radionuclides might be analyzed with minimal sample preparation and the individual specific activities of each alpha emitting species found. A theoretical relationship describing the pulse height distribution of an infinitely thick source of alpha activity is developed. This relationship is then fit to uranium and thorium

Kevin A. Phoenix

1997-01-01

396

Future prospects for targeted alpha therapy.  

PubMed

The objectives in the application of targeted alpha therapy (TAT) for cancer therapy are reviewed. These relate to elimination of isolated cancer cells, cell clusters and tumors. Requirements for isolated cancer cells are good cellular targeting, high specific activity, and very short range. The regression of cell clusters in the peri-vascular space requires high capillary permeability and short range cross fire whereas for developed tumors, good bioavailabilty and anti- capillary activity are essential. Current sources of alpha radiation are reviewed and the prospects for commercial sources for clinical application are discussed. The Ac:Bi generator is the most practical alpha source, bringing therapy to Nuclear Medicine with the same practicality as the Mo:Tc generator has for imaging. The status quo of TAT is briefly reviewed with respect to dose normalization, real time microdosimetry and biological dosimetry for deterministic and stochastic effects and toxicity. The role of Monte Carlo calculations is emphasized. The strengths and weaknesses of TAT are examined and the way forward for clinical acceptance is discussed. PMID:22202156

Allen, Barry J

2011-10-01

397

The Alpha Dynamo Effects in Laboratory Plasmas  

SciTech Connect

A concise review of observations of the alpha dynamo effect in laboratory plasmas is given. Unlike many astrophysical systems, the laboratory pinch plasmas are driven magnetically. When the system is overdriven, the resultant instabilities cause magnetic and flow fields to fluctuate, and their correlation induces electromotive forces along the mean magnetic field. This alpha-effect drives mean parallel electric current, which, in turn, modifies the initial background mean magnetic structure towards the stable regime. This drive-and-relax cycle, or the so-called self-organization process, happens in magnetized plasmas in a timescale much shorter than resistive diffusion time, thus it is a fast and unquenched dynamo process. The observed alpha-effect redistributes magnetic helicity (a measure of twistedness and knottedness of magnetic field lines) but conserves its total value. It can be shown that fast and unquenched dynamos are natural consequences of a driven system where fluctuations are statistically either not stationary in time or not homogeneous in space, or both. Implications to astrophysical phenomena will be discussed.

Hantao Ji; Stewart C. Prager

2001-10-16

398

Lyman Alpha Mapping Project (LAMP) Brightness Maps  

NASA Astrophysics Data System (ADS)

The Lyman Alpha Mapping Project (LAMP) is an ultraviolet (UV) spectrograph on the Lunar Reconnaissance Orbiter (LRO) that is designed to map the lunar albedo at far-UV wavelengths. LAMP primarily measures interplanetary Hydrogen Lyman-alpha sky-glow and far-UV starlight reflected from the night-side lunar surface, including permanently shadowed regions (PSRs) near the poles. Dayside observations are also obtained. Brightness maps sorted by wavelength (including the Lyman-alpha wavelength of 121.6 nm) are reported for the polar regions, with a few regions of interest reported in more detail. LAMP's spectral range of 58 nm to 196 nm includes a water ice spectral feature near 160 nm, which provides a diagnostic tool for detecting water on the lunar surface that is complementary to recent discoveries using infrared and radio frequency techniques. Progress towards producing far-UV albedo maps and searching for water ice signatures will be reported. We'll discuss how LAMP data may address questions regarding how water is formed on the moon, transported through the lunar atmosphere, and deposited in the PSRs.

Retherford, Kurt D.; Gladstone, G.; Stern, S.; Egan, A. F.; Miles, P. F.; Parker, J. W.; Greathouse, T. K.; Davis, M. W.; Slater, D. C.; Kaufmann, D. E.; Versteeg, M. H.; Feldman, P. D.; Hurley, D. M.; Pryor, W. R.; Hendrix, A. R.

2010-10-01

399

Molecular characterization of alpha-thalassemia in the Dohuk region of Iraq.  

PubMed

The molecular basis of alpha-thalassemia (alpha-thal) has been addressed by several studies from the eastern Mediterranean region, but not from Iraq. To address this issue, we studied 51 individuals with unexplained hypochromia and/or microcytosis, as well as nine patients with documented Hb H disease from the Dohuk region in northern Iraq. We used multiplex gap-polymerase chain reaction (gap-PCR), reverse hybridization, and sequencing for this purpose. It was found that the most common genotypes in those with unexplained hypochromia and/or microcytosis were -alpha(3.7)/alpha alpha, followed by - -(MED-I)/alpha alpha, then -alpha(3.7)/-alpha (3.7), respectively, detected in 84.3% of the above individuals. Other genotypes identified sporadically were -alpha(4.2)/alpha alpha, alpha(poly A1)alpha/alpha alpha (AATAAA>AATAAG), alpha(Adana)alpha/alpha alpha [Hb Adana, codon 59 (Gly-->Asp) or HBA1:c.179G>A], and alpha(Evanston)alpha/alpha alpha [Hb Evanston, codon 14 (Trp-->Arg) or HBA1:c.43 T>C]. Three cases (5.88%) remained uncharacterized even after sequencing. All nine Hb H cases carried the -alpha(3.7)/- -(MED-I) genotype. Such findings are rather different from those in other eastern Mediterranean populations, particularly with relevance to an Hb H molecular basis. PMID:19205971

Al-Allawi, Nasir A S; Badi, Ameer I A; Imanian, Hasham; Nikzat, Nooshin; Jubrael, Jaladet M S; Najmabadi, Hossein

2009-01-01

400

Alpha-radioimmunotherapy with At-211: Evaluations and imaging on normal tissues and tumors.  

E-print Network

??Alpha-radioimmunotherapy (alpha-RIT) is an internal conformal radiotherapy at the cellular level using alpha-particle emitting radionuclides. Alpha-particles have a very short range in tissues (<100 micrometer)… (more)

Bäck, Tom

2011-01-01

401

Alpha Particle Physics Experiments in the Tokamak Fusion Test Reactor  

SciTech Connect

Alpha particle physics experiments were done on the Tokamak Fusion Test Reactor (TFTR) during its deuterium-tritium (DT) run from 1993-1997. These experiments utilized several new alpha particle diagnostics and hundreds of DT discharges to characterize the alpha particle confinement and wave-particle interactions. In general, the results from the alpha particle diagnostics agreed with the classical single-particle confinement model in magnetohydrodynamic (MHD) quiescent discharges. Also, the observed alpha particle interactions with sawteeth, toroidal Alfvén eigenmodes (TAE), and ion cyclotron resonant frequency (ICRF) waves were roughly consistent with theoretical modeling. This paper reviews what was learned and identifies what remains to be understood.

Budny, R.V.; Darrow, D.S.; Medley, S.S.; Nazikian, R.; Zweben, S.J.; et al.

1998-12-14

402

Detection of alpha radiation in a beta radiation field  

DOEpatents

An apparatus and method for detecting alpha particles in the presence of high activities of beta particles utilizing an alpha spectrometer. The apparatus of the present invention utilizes a magnetic field applied around the sample in an alpha spectrometer to deflect the beta particles from the sample prior to reaching the detector, thus permitting detection of low concentrations of alpha particles. In the method of the invention, the strength of magnetic field required to adequately deflect the beta particles and permit alpha particle detection is given by an algorithm that controls the field strength as a function of sample beta energy and the distance of the sample to the detector.

Mohagheghi, Amir H. (Albuquerque, NM); Reese, Robert P. (Edgewood, NM)

2001-01-01

403

Polypeptide chain elongation factor 1 alpha (EF-1 alpha) from yeast: nucleotide sequence of one of the two genes for EF-1 alpha from Saccharomyces cerevisiae.  

PubMed Central

Messenger RNA for yeast cytosolic polypeptide chain elongation factor 1 alpha (EF-1 alpha) was partially purified from Saccharomyces cerevisiae. Double-stranded complementary DNA (cDNA) was synthesized and cloned in Escherichia coli with pBR327 as a vector. Recombinant plasmid carrying yEF-1 alpha cDNA was identified by cross-hybridization with the E. coli tufB gene and the yeast mitochondrial EF-Tu gene (tufM) under non-stringent conditions. A yeast gene library was then screened with the EF-1 alpha cDNA and several clones containing the chromosomal gene for EF-1 alpha were isolated. Restriction analysis of DNA fragments of these clones as well as the Southern hybridization of yeast genomic DNA with labelled EF-1 alpha cDNA indicated that there are two EF-1 alpha genes in S. cerevisiae. The nucleotide sequence of one of the two EF-1 alpha genes (designated as EF1 alpha A) was established together with its 5'- and 3'-flanking sequences. The sequence contained 1374 nucleotides coding for a protein of 458 amino acids with a calculated mol. wt. of 50 300. The derived amino acid sequence showed homologies of 31% and 32% with yeast mitochondrial EF-Tu and E. coli EF-Tu, respectively. Images Fig. 2. PMID:6383821

Nagata, S; Nagashima, K; Tsunetsugu-Yokota, Y; Fujimura, K; Miyazaki, M; Kaziro, Y

1984-01-01

404

Elevated levels of tumor necrosis factor alpha (TNF-alpha) in human immunodeficiency virus type 1-transgenic mice: prevention of death by antibody to TNF-alpha.  

PubMed

Homozygous human immunodeficiency virus type 1 (HIV-1)-transgenic mice (Tg26) appear normal at birth but die within 3 to 4 weeks. The skin of these animals shows diffuse scaling and high-level expression of both HIV-1 mRNA and gp120. Previous experiments showed that treatment with human chorionic gonadatropin (hCG) prevented death and the expression of HIV-1 mRNA and gp120. The present experiments were initiated to study the role of tumor necrosis factor alpha (TNF-alpha) in HIV-1-induced pathology. Examination of the sera of Tg26 mice revealed a 50-fold increase in TNF-alpha levels compared to those in nontransgenic mice. Treatment with antibody to TNF-alpha prevented death, resulted in near normal growth, and produced a marked decrease in skin lesions and a profound reduction in the expression of HIV-1 mRNA and gp120. Both TNF-alpha antibody and hCG reduced TNF-alpha levels in sera by approximately 75%. We conclude that TNF-alpha contributes in a major way to HIV-1-induced pathology in transgenic mice and that both hCG and antibody to TNF-alpha prevent the development of pathology by suppressing the level of TNF-alpha. PMID:12388730

De, Swapan K; Devadas, Krishnakumar; Notkins, Abner Louis

2002-11-01

405

Functional and Genomic Analyses of Alpha-Solenoid Proteins  

PubMed Central

Alpha-solenoids are flexible protein structural domains formed by ensembles of alpha-helical repeats (Armadillo and HEAT repeats among others). While homology can be used to detect many of these repeats, some alpha-solenoids have very little sequence homology to proteins of known structure and we expect that many remain undetected. We previously developed a method for detection of alpha-helical repeats based on a neural network trained on a dataset of protein structures. Here we improved the detection algorithm and updated the training dataset using recently solved structures of alpha-solenoids. Unexpectedly, we identified occurrences of alpha-solenoids in solved protein structures that escaped attention, for example within the core of the catalytic subunit of PI3KC. Our results expand the current set of known alpha-solenoids. Application of our tool to the protein universe allowed us to detect their significant enrichment in proteins interacting with many proteins, confirming that alpha-solenoids are generally involved in protein-protein interactions. We then studied the taxonomic distribution of alpha-solenoids to discuss an evolutionary scenario for the emergence of this type of domain, speculating that alpha-solenoids have emerged in multiple taxa in independent events by convergent evolution. We observe a higher rate of alpha-solenoids in eukaryotic genomes and in some prokaryotic families, such as Cyanobacteria and Planctomycetes, which could be associated to increased cellular complexity. The method is available at http://cbdm.mdc-berlin.de/~ard2/. PMID:24278209

Fournier, David; Palidwor, Gareth A.; Shcherbinin, Sergey; Szengel, Angelika; Schaefer, Martin H.; Perez-Iratxeta, Carol; Andrade-Navarro, Miguel A.

2013-01-01

406

alpha-Thalassaemia in the population of Cyprus.  

PubMed

We have determined the alpha-thalassaemia (alpha-thal) determinants in 78 patients with Hb H disease from Cyprus; 25 were Turkish Cypriots and 53 were Greek Cypriots. Four deletional and three non-deletional alpha-thal alleles were present; the -alpha(3.7 kb) alpha-thal-2 and the --MED-I alpha-thal-1 were most frequently seen; --MED-II and -(alpha)20.5 deletions occurred at considerably lower frequencies. About 15% of all chromosomes carried a non-deletional alpha-thal-2 allele; of these the 5 nucleotide (nt) deletion at the first intervening sequence (IVS-I) donor splice site was present in approximately 8% of all chromosomes. Two types of polyadenylation signal (poly A) mutations were observed. No striking frequency differences were seen between Greek and Turkish Cypriot patients. Combinations of the various types of alpha-thal resulted in eight different forms of Hb H disease. The phenotypes were comparable except for great variations in the level of Hb H which was highest (average approximately 22%) in the 12 patients with the alpha 5nt alpha/--MED-I combination. One patient with the same form of Hb H disease but with an additional beta-thal (IVS-I-110,G-->A) heterozygosity had a most severe microcytosis and hypochromia with < 1% Hb H. Variations in the level of Hb H might correlate with the severity of the disease, although this was not evident from the haematological data. PMID:7734346

Baysal, E; Kleanthous, M; Bozkurt, G; Kyrri, A; Kalogirou, E; Angastiniotis, M; Ioannou, P; Huisman, T H

1995-03-01

407

Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women  

PubMed Central

Endometriosis is a disorder that affects 5% of the normal population but is present in up to 40% of women with pelvic pain and/or infertility. Recent evidence suggests that the endometrium of women with endometriosis exhibits progesterone insensitivity. One endometrial protein that fluctuates in response to progesterone is the estrogen receptor-alpha (ER alpha), being down-regulated at the time of peak progesterone secretion during the window of implantation. Here we demonstrate that the biomarker of uterine receptivity, beta 3 integrin subunit, is reduced or absent in some women with endometriosis and that such defects are accompanied by inappropriate over-expression of ER alpha during the mid-secretory phase. Using a well-differentiated endometrial cell line we showed that the beta 3 integrin protein is negatively regulated by estrogen and positively regulated by epidermal growth factor (EGF). By competing against estrogen with various selective estrogen receptor modulators (SERMs) and estrogen receptor agonists and antagonists, inhibition of expression of the beta 3 integrin by estrogen can be mitigated. In conclusion, we hypothesize that certain types of uterine receptivity defects may be caused by the loss of appropriate ER alpha down-regulation in the mid-secretory phase, leading to defects in uterine receptivity. Such changes might be effectively treated by timely administration of the appropriate anti-estrogens to artificially block ER alpha and restore normal patterns of gene expression. Such treatments will require further clinical studies. PMID:17118173

Lessey, Bruce A; Palomino, Wilder A; Apparao, KBC; Young, Steven L; Lininger, Ruth A

2006-01-01

408

Determination of $\\alpha_{s}$ using Jet Rates at LEP with the OPAL detector  

E-print Network

Hadronic events produced in e+e- collisions by the LEP collider and recorded by the OPAL detector were used to form distributions based on the number of reconstructed jets. The data were collected between 1995 and 2000 and correspond to energies of 91 GeV, 130-136 GeV and 161-209 GeV. The jet rates were determined using four different jet-finding algorithms (Cone, JADE, Durham and Cambridge). The differential two-jet rate and the average jet rate with the Durham and Cambridge algorithms were used to measure alpha(s) in the LEP energy range by fitting an expression in which order alpah_2s calculations were matched to a NLLA prediction and fitted to the data. Combining the measurements at different centre-of-mass energies, the value of alpha_s (Mz) was determined to be alpha(s)(Mz)=0.1177+-0.0006(stat.)+-0.0012$(expt.)+-0.0010(had.)+-0.0032

Abbiendi, G; Åkesson, P F; Alexander, G; Anagnostou, G; Anderson, K J; Asai, S; Axen, D; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, F L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, R J; Herten, G; Heuer, R D; Hill, J C; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, D; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krasznahorkay, A; Krieger, P; Von Krogh, J; Kühl, T; Kupper, M; Lafferty, G D; Landsman, H; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Mashimo, T; Mättig, P; McKenna, J A; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rossi, A M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

2006-01-01

409

Peptides derived from the human laminin alpha4 and alpha5 chains exhibit antimicrobial activity.  

PubMed

Laminins are a family of heterotrimeric extracellular matrix glycoproteins in the basement membrane of different tissues and are composed of alpha, beta, and gamma chains. In mammals, five different alpha chains, three beta chains, and three gamma chains have been identified that assemble into 15 different laminins. Each alpha-chain possesses a C-terminal globular domain which can be subdivided into the five subdomains LG1-LG5. LG1-LG3 modules are connected to LG4-LG5 by a linker domain which is known to be sensitive to proteolytic processing. Here, we show that peptides derived from the human laminin alpha4 and alpha5 chain, exhibit a dose-dependent antimicrobial activity against gram-positive and gram-negative bacteria. Furthermore, we show that these peptides permeabilize the bacterial membrane and are able to bind to bacterial DNA. Interestingly, the ability to kill the microorganisms correlated with their ability to bind to heparin. These data suggest that extracellular matrix components are able to protect the respective tissues from invading pathogens and are part of the host defense response. PMID:20433883

Senyürek, Ilknur; Klein, Gerd; Kalbacher, Hubert; Deeg, Martin; Schittek, Birgit

2010-08-01

410

Determination of alpha_s using Jet Rates at LEP with the OPAL detector  

E-print Network

Hadronic events produced in e+e- collisions by the LEP collider and recorded by the OPAL detector were used to form distributions based on the number of reconstructed jets. The data were collected between 1995 and 2000 and correspond to energies of 91 GeV, 130-136 GeV and 161-209 GeV. The jet rates were determined using four different jet-finding algorithms (Cone, JADE, Durham and Cambridge). The differential two-jet rate and the average jet rate with the Durham and Cambridge algorithms were used to measure alpha(s) in the LEP energy range by fitting an expression in which order alpah_2s calculations were matched to a NLLA prediction and fitted to the data. Combining the measurements at different centre-of-mass energies, the value of alpha_s (Mz) was determined to be alpha(s)(Mz)=0.1177+-0.0006(stat.)+-0.0012$(expt.)+-0.0010(had.)+-0.0032(theo.) \\.

The OPAL Collaboration; G. Abbiendi

2005-07-11

411

On the mechanism of the chemical and enzymic oxygenations of alpha-oxyprotohemin IX to Fe.biliverdin IX alpha.  

PubMed Central

alpha-Oxyprotohemin IX, an early intermediate in heme catabolism, was synthesized and its autoxidation to biliverdin IX alpha was studied. In anaerobic aqueous pyridine, alpha-oxyprotohemin (hexacoordinated) underwent autoreduction to yield an Fe(II) alpha-oxyprotoporphyrin pi-neutral radical bis(pyridine) complex, which reacted with an equimolar amount of dioxygen to give pyridine.verdohemochrome IX alpha and CO in 75-80% yield via an intermediate with an absorption maximum at 893 nm. Verdohemochrome IX alpha did not react with further dioxygen. Reconstituted apomyoglobin.alpha-oxyprotohemin IX complex (pentacoordinated) reacted with an equimolar amount of dioxygen to form an Fe(II) oxyporphyrin pi-neutral radical intermediate, which rearranged to a green compound (lambda max 660 and 704 nm) with elision of CO. The green product, which is probably an apomyoglobin.verdoheme pi-radical complex, reacted with another equimolar amount of dioxygen to give Fe(III).biliverdin IX alpha. Demetallation of this gave biliverdin IX alpha in overall yield of 70-75%. These results indicate that the sequence of oxyheme autoxidation in the presence of apomyoglobin is alpha-oxyprotoheme IX O2----CO----verdohemochrome IX alpha pi-radical O2----Fe(III).biliverdin IX alpha. A similar mechanism may prevail in vivo. The hexa- and pentacoordinated Fe(II) pi-radical form of the oxyporphyrin is crucial in triggering the autoxidation of the complex to verdohemochrome IX alpha. Further oxygenation of verdohemochrome IX alpha to Fe(III).biliverdin IX alpha occurred only in the pentacoordinated apomyoglobin.verdoheme Fe(II) complex. PMID:3456152

Sano, S; Sano, T; Morishima, I; Shiro, Y; Maeda, Y

1986-01-01

412

Differential expression of alpha 2 macroglobulin in response to dietylstilbestrol and in ovarian carcinomas in chickens  

PubMed Central

Background Alpha 2 macroglobulin (A2M; also known as ovostatin), a homotetrameric protein with four disulfide-linked subunits, has the unique feature of inactivating/inhibiting most known proteases including serine-, threonine-, cysteine-, aspartic- and metalloproteases. In chickens, A2M has been identified and characterized biochemically, but little is known of its functional role(s) in the oviduct, hormonal regulation of expression or its expression in ovarian carcinomas in chickens. Therefore, we investigated estrogen regulation of A2M gene expression during development of the chicken oviduct, and its expression in normal and cancerous ovaries from chickens. Methods To determine tissue-specific expression of A2M in chickens, we collected various organs from male and female chickens and performed RT-PCR analyses. To examine A2M gene expression in the oviduct of 1-week-old female chicks that received a subcutaneous implant of 15 mg DES in the abdominal region for 20 days, we performed RT-PCR, qPCR and in situ hybridization analyses using cDNAs from control- (n = 5) and DES-treated oviducts (n = 5), and then each segment of the oviduct from DES-treated chicks. To determine if A2M is a biomarker of ovarian cancer in hens, we collected cancerous (n = 10) ovaries from a total of 136 chickens which had completely stopped egg-laying and performed RT-PCR and in situ hybridization analyses. Results We found that A2M is most abundant in the chicken oviduct, specifically luminal (LE) and glandular epithelia (GE), but it was not detected in any other tissues of either sex. We then determined that DES (dietylstilbestrol, a synthetic nonsteroidal estrogen) increased A2M mRNA only in LE and GE of the oviduct of chicks. Further, expression of A2M was most abundant in GE of endometrioid adenocarcinoma of cancerous, but not normal ovaries of hens. Conclusions Collectively, results of the present study indicate that A2M is novel estrogen-stimulated gene expressed in LE and GE of the chicken oviduct and may be used for monitoring effects of therapies for ovarian cancer in laying hens. PMID:21978460

2011-01-01

413

Comparative behavioral characterization of the neuroactive steroids 3 alpha-OH,5 alpha-pregnan-20-one and 3 alpha-OH,5 beta-pregnan-20-one in rodents.  

PubMed

Pregnan steroids have been shown to possess anesthetic, hypnotic, anticonvulsant and anxiolytic properties. In this study, two endogenous neuroactive steroid isomers, 3 alpha-hydroxy-5 alpha-pregnan-20-one (3 alpha,5 alpha-P) and 3 alpha-hydroxy-5 beta-pregnan-20-one 3 alpha,5 beta-P), were studied for differences in their pharmacological properties using behavioral assays. 3 alpha,5 alpha-P and 3 alpha,5 beta-P were similar in their potencies and efficacies in blocking pentylenetetrazol-induced seizures in mice (ED50: 3 alpha, 5 alpha-P = 2.8 mg/kg and 3 alpha,5 beta-P = 3.0 mg/kg). Similarly, both neuroactive steroids produced roto-rod deficits within the same range of potency (TD50: 3 alpha,5 alpha-P = 18.8 mg/kg and 3 alpha,5 beta-P = 21.2 mg/kg). However, in animal models of anxiety, subtle differences were observed between the two isomers. In both the light/dark transition test and elevated plus-maze, 3 alpha,5 beta-P was more efficacious than 3 alpha,5 alpha-P, though both compounds had similar potencies. In the Geller-Seifter test, 3 alpha,5 beta-P was more potent and efficacious than 3 alpha,5 alpha-P. Neither compound had significant effects on unpunished responding within the dose range tested. Both compounds produced similar biphasic curves in the locomotor test. All together, the data indicate that 3 alpha,5 alpha-P and 3 alpha,5 beta-P have similar anticonvulsant activity, but the 5 beta-isomer possesses more potent and efficacious anxiolytic properties than the 5 alpha-isomer. PMID:7597124

Wieland, S; Belluzzi, J D; Stein, L; Lan, N C

1995-03-01

414

Réactions Organiques des Alcools en Conditions Hydrothermales.  

E-print Network

??Cette thèse a pour objectif d'étudier les réactions des alcools en conditions hydrothermales. Dans une phase préliminaire, le phényl-éthanediol a été étudiés. Après aldolisation, cyclisation… (more)

Smutek, Bernhard

2011-01-01

415

TRANSMUTATION DES PARTICULES FONDAMENTALES. CHANGEMENT DE SPIN  

E-print Network

123. TRANSMUTATION DES PARTICULES FONDAMENTALES. CHANGEMENT DE SPIN Par A. PROCA. Institut Henri'entre elles, comme autant d'états distincts d'un seul et même corpus- cule et de regarder les transmutations

Boyer, Edmond

416

Supervision Dcentralise des Chorgraphies de Services  

E-print Network

, la croissance continuelle des entreprises incite celles-ci à externali- ser et à sous traiter-organisationnelle peut être mise en oeuvre afin de permettre la coordination et la synchronisation de ces différentes

Paris-Sud XI, Université de

417

Index des mots-cls Keywords index  

E-print Network

Index des mots-clés Keywords index A Abies, 823 Abies alba, 265 acacia, 93 Acacia cyanophylla Lindl., 335 Acacia mearnsii De Wild., 833 acclimation, 19 AFLP, 627 AFLP, SSR, EST markers, 637 Agrobacterium

Boyer, Edmond

418

Universit de Franche-Comt Programme des  

E-print Network

: Institut d'administration des entreprises SCD : Service commun de documentation de l'Université CLA problèmes liés à la santé : stress, addiction, interaction avec le monde hospitalier, la technologie au

Jeanjean, Louis

419

Habilitation Diriger Des Recherches Prsente devant  

E-print Network

des super héros qui ont et oeuvrent toujours pour le vivant et la Santé, au travers de la SFGBM mais compris, le fruit dun travail collectif et de collaborations multiples impliquant bien sur dautres

Paris-Sud XI, Université de

420

SUR QUELQUES POLLINISATEURS DES LGUMINEUSES FOURRAGRES  

E-print Network

blanc (Trifolium repens L.). LINSLEY (1946) donne le premier inventaire des pollinisateurs de la Luzerne plan économique :la Luzerne (Medicago sativa L.), le Trèfle violet (Trifolium pratense L.) et le Trèfle

Boyer, Edmond

421

HACK Patrice Les coulisses des assistances tlphoniques  

E-print Network

HACK Patrice 1 ________________________________________________________________ Les coulisses des Criminologie et de Police Technique et Scientifique LXV (2012) 110" #12;HACK Patrice 2 1 ­ Données et méthode

Paris-Sud XI, Université de

422

Separation and determination of denatured alpha(s1)-, alpha(s2)-, beta- and kappa-caseins by hydrophobic interaction chromatography in cows', ewes' and goats' milk, milk mixtures and cheeses.  

PubMed

Caseins alpha(s1)-, alpha(s2)-, beta- and kappa- from raw cows', ewes' and goats' milk were separated and determined by hydrophobic interaction chromatography (HIC) by using a Propyl column (Eichrom) in the presence of 8.0 M urea in the mobile phase. The method is based on fast and easy solubilization of real raw samples by 4.0 M guanidine thiocyanate followed by the HIC analysis, without any preliminary precipitation or separation of the casein fraction. Elution conditions have been optimized by analyzing commercial single bovine standard caseins and their mixture. In the optimized chromatographic conditions the four casein fractions were separated in less than 45 min. A linear relationship between the concentration of casein and peak area (UV absorbance detector at 280 nm) has been obtained over the concentration range of 0.5 to 40 microM. The detection limit for alpha-, beta- and kappa-caseins ranged between 0.35 and 0.70 microM. The precision of the method was evaluated, the coefficient of variation for alpha-, beta- and kappa-casein determination ranging between 3.0 and 6.0%. The method has been validated by the analysis of reference skim milk powder (BCR-063R) certificated for total nitrogen content. The method was applied to commercial casein mixture and to the qualitative and quantitative analysis of casein fractions in unprocessed, raw cows', goats' and ewes' milk (10 samples analyzed for each species), in one sample of unprocessed buffalos' milk and in commercial cheeses (mozzarella, robiola, ricotta and stracchino). Binary mixtures of milk (cow/goat and cow/ewe) were also analyzed and the ratio between casein peak areas (alpha(s1)/kappa, alpha(s2)/beta, beta/kappa and alpha(s2)/alpha(s1)) of the HIC chromatograms was proposed and discussed in order to evaluate a possible application of this method to detect milk adulteration. PMID:12779219

Bramanti, Emilia; Sortino, Chandra; Onor, Massimo; Beni, Francesca; Raspi, Giorgio

2003-04-25

423

Organocatalyzed cyclopropanation of alpha-substituted alpha,beta-unsaturated aldehydes: enantioselective synthesis of cyclopropanes bearing a chiral quaternary center.  

PubMed

An enantioselective cyclopropanation of alpha-substituted alpha,beta-unsaturated aldehydes with bromomalonate has been successfully developed through a domino Michael/alpha-alkylation strategy. The method allows the efficient formation of cyclopropanes bearing a quaternary carbon stereocenter at the alpha-position of the aldehydes by using iminium/enamine catalysis and gives a nice extension on the organocatalytic cyclopropanation of bromomalonate and alpha,beta-unsaturated aldehydes previously reported by other groups. Very good yields (up to 81%) and enantioselectivities (up to 97% ee) have been obtained. The optically active cyclopropane derivatives are of high synthetic interest as useful targets for further elaboration into more complex structures. PMID:20512823

Terrasson, Vincent; van der Lee, Arie; de Figueiredo, Renata Marcia; Campagne, Jean Marc

2010-07-12

424

La violence sociale est-elle une violence masculine ?1 En France, 88% des personnes mises en cause par la justice sont des hommes, 94 % des actes  

E-print Network

La violence sociale est-elle une violence masculine ?1 En France, 88% des personnes mises en cause enregistrés suite à des violences conjugales, 166 sont causés par des hommes... Quelles explications peut ou violences sur autrui. L'étude, portant sur 6000 sanctions, a été complétée par des entretiens

Paris-Sud XI, Université de

425

Megacystis, Mydriasis, and Ion Channel Defect in Mice Lacking the alpha 3 Neuronal Nicotinic Acetylcholine Receptor  

Microsoft Academic Search

The alpha 3 subunit of the neuronal nicotinic acetylcholine receptor is widely expressed in autonomic ganglia and in some parts of the brain. The alpha 3 subunit can form heteromultimeric ion channels with other alpha subunits and with alpha 2 and alpha 4 subunits, but its function in vivo is poorly understood. We prepared a null mutation for the alpha

Wei Xu; Shari Gelber; Avi Orr-Urtreger; Dawna Armstrong; Richard A. Lewis; Ching-Nan Ou; James Patrick; Lorna Role; Mariella de Biasi; Arthur L. Beaudet

1999-01-01

426

75 FR 25319 - Agency Information Collection (Survey of Satisfaction With the Disability Evaluation System (DES...  

Federal Register 2010, 2011, 2012, 2013, 2014

...New (DES)] Agency Information Collection (Survey of Satisfaction With the Disability Evaluation System (DES)) Activities...DES).'' SUPPLEMENTARY INFORMATION: Title: Survey of Satisfaction with the Disability Evaluation System (DES). OMB...

2010-05-07

427

Quelques tendances actuelles en histoire des mathematiques.  

E-print Network

Development, sous la dir. de Joseph W. Dauben et Christoph J. Scriba, Birkh¨auser, B^ale, 2002, p. 6. 3 Voir Catherine Goldstein, Jeremy Gray et Jim Ritter, dir., L'Europe math´ematique : histoire, mythes, identit´ematiques `a des ´epoques et dans des cultures diff´erentes. Dans un ouvrage r´ecent dirig´e par Joseph Dauben

Aubin, David

428

L'occupation des espaces littoraux mditerranens  

E-print Network

I 1 i I L'occupation des espaces littoraux méditerranéens Olivier GODARD Bienqu'onpuisse dire d'accroissement considérablede lapression sur l'espace littoral :à l'île de Ré, le mètre carré, qui était à 2 F en 1953 est passé natu- rellement autour des principaux centres portuaires du littoral, déterminés par les profondeurs d

Paris-Sud XI, Université de

429

Die Erheblichkeit Des Humanismus In Durftiger Zeit  

E-print Network

Objekts wie ihn auch Auguste Comte verstanden hat. Die Kritik ist aber nicht stichhaltig gegenüber dem Positivismus des sinnhaften Erlebnisses, den Edmund Husserl in seinem Entwurf der Phänomenologie hervorbringt. Daher sind wir zu dem Schluß gekommen... ganz deutlich in Masaryks Humanismus geäussert, aber nicht nur dort. Der Gründer des modernen Positivismus, Auguste Com te, war auch derjenige Philosoph, der einen "Kult der Humanität" vorgeschlagen hat. Der britische Empirizist John Locke hat die...

Kohak, Erazim

430

LE PROBLME DES NOMBRES CONGRUENTS Pierre Colmez  

E-print Network

'est pas un nombre congruent. #12;2 PIERRE COLMEZ C'est une des nombreuses utilisations que Fermat implique donc le théorème de Fermat3 pour l'exposant 4. Exemple 4 (Zagier). -- L'entier 157 est congruentLE PROBL�ME DES NOMBRES CONGRUENTS par Pierre Colmez Résumé. -- Ce texte est une introduction à la

Colmez, Pierre

431

Sedimentologie des Lias der Berchtesgadener Kalkalpen  

Microsoft Academic Search

Zusammenfassung  Ausgehend von der herrschenden Vorstellung einer Transgression roter Liaskalke zur Zeit des oberen Unterlias über ein subaerisch verkarstetes Dachsteinkallerelief, untersuchte ich die Liassedimente in den Berchtesgadener Alpen eingehender und unternahm vergleichende Begehungen im östlichen Hagengebirge, im Steinernen Meer und in den Steinbrüchen von Adnet.Die Sedimente des Lias liegen in einer Graukalk- und einer abwechslungsreicheren Rotkalk-Fazies (F.Fabricius 1962) vor. Ammoniten zeigten,

Hermann Jurgan

1968-01-01

432

Robustness of truncated $\\alpha\\Omega$ dynamos with a dynamic $\\alpha$  

E-print Network

In a recent work (Covas et al. 1997), the behaviour and the robustness of truncated $\\alpha\\Omega$ dynamos with a dynamic $\\alpha$ were studied with respect to a number of changes in the driving term of the dynamic $\\alpha$ equation, which was considered previously by Schmalz and Stix (1991) to be of the form $\\sim A_{\\phi}B_{\\phi}$. Here we review and extend our previous work and consider the effect of adding a quadratic quenching term of the form effects on the dynamics of the related truncated systems. We also find intervals of (negative) dynamo numbers, in the system considered by Schmalz and Stix (1991), for which there is sensitivity with respect to small changes in the dynamo number and the initial conditions, similar to what was found in our previous work. This latter behaviour may be of importance in producing the intermittent type of behaviour observed in the sun.

Covas, E; Tavakol, R K; Brandenburg, A; Covas, Eurico; Tworkowski, Andrew; Tavakol, Reza; Brandenburg, Axel

1997-01-01

433

Bestimmung der Körperlänge und des Lebensalters menschlicher Feten auf Grund der ersten Hand und ersten Fußwurzelknochenmaße, sowie der Größe des Atlas und des Epistropheus-Wirbelbogens  

Microsoft Academic Search

Es wurden die Größenmaße des I. Hand- und des I. Fußwurzelknochens und des Atlas- und Epistropheuswirbelbogens von 138 totgeborenen oder wenige Stunden nach der Geburt gestorbenen menschlichen Feten — 71 Knaben und 67 Mädchen mit einer Länge von 9–55 cm — bestimmt.

I. Gy. Fazekas; F. Kósa

1967-01-01

434

Expression of alpha/beta interferons (IFN-alpha/beta) and their relationship to IFN-alpha/beta-induced genes in lymphocytic choriomeningitis.  

PubMed Central

Expression of alpha interferon (IFN-alpha)-, IFN-beta-, and IFN-alpha/beta-induced genes was monitored during the development of lymphocytic choriomeningitis (LCM) to assess whether a restricted influence of these antiviral cytokines could be found in the central nervous system (CNS). High levels of IFN-alpha (83 +/- 42 U/ml) were present in the blood of LCM virus-infected mice 3 days postinfection, whereas IFN-beta was not detected (< 1.0 U/ml) at any time point. Spleens contained high levels of IFN-alpha and IFN-beta mRNAs at days 1 and 3 postinfection, whereas no IFN-alpha mRNA and only low levels of IFN-beta mRNA were detected in brains. In situ hybridization showed IFN-alpha mRNA-expressing cells in the marginal zones of the spleen and in the subcapsular sinus and outer cortex of cervical lymph nodes. The expression of 2',5'-oligoadenylate synthetase (2',5'-OAS) mRNA followed the expression of IFN-beta mRNA in the brain, whereas 2',5'-OAS mRNA in the periphery was associated with systemic IFN-alpha. The localization of IFN-alpha-expressing cells in the spleen and lymph nodes in proximity to T- and B-cell compartments is consistent with a role for these cytokines in immune regulation. Furthermore, the absence of IFN-alpha and the relatively low level and delayed expression of IFN-beta in the brain suggest that the CNS is an especially vulnerable organ for virus replication. With certain strains of LCM virus, the absence of early antiviral IFN-alpha/beta activity and preferential virus growth in the brain might lead to targeted T-cell inflammation of the CNS, resulting in death of the animal. Images PMID:7933119

Sandberg, K; Eloranta, M L; Campbell, I L

1994-01-01

435

Far-Infrared and Millimeter Continuum Studies of K-Giants: Alpha Boo and Alpha Tau  

NASA Technical Reports Server (NTRS)

We have imaged two normal, non-coronal, infrared-bright K-giants, alpha Boo and alpha Tau, in the 1.4-millimeter and 2.8-millimeter continuum using BIMA. These stars have been used as important absolute calibrators for several infrared satellites. Our goals are: (1) to probe the structure of their upper photospheres; (2) to establish whether these stars radiate as simple photospheres or possess long-wavelength chromospheres; and (3) to make a connection between millimeter-wave and far-infrared absolute flux calibrations. To accomplish these goals we also present ISO Long Wavelength Spectrometer (LWS) measurements of both these K-giants. The far-infrared and millimeter continuum radiation is produced in the vicinity of the temperature minimum in a Boo and a Tau, offering a direct test of the model photospheres and chromospheres for these two cool giants. We find that current photospheric models predict fluxes in reasonable agreement with those observed for those wavelengths which sample the upper photosphere, namely less than or equal to 170 micrometers in alpha Tau and less than or equal to 125 micrometers in alpha Boo. It is possible that alpha Tau is still radiative as far as 0.9 - 1.4 millimeters. We detect chromospheric radiation from both stars by 2.8 millimeters (by 1.4 millimeters in alpha Boo), and are able to establish useful bounds on the location of the temperature minimum. An attempt to interpret the chromospheric fluxes using the two-component "bifurcation model" proposed by Wiedemann et al. (1994) appears to lead to a significant contradiction.

Cohen, Martin; Carbon, Duane F.; Welch, William J.; Lim, Tanya; Forster, James R.; Goorvitch, David; Thigpen, William (Technical Monitor)

2002-01-01

436

Organization Advisor Type Name Email Address Alpha Delta Pi Chapter Advisor Allison Thompson aburkethompson@hotmail.com  

E-print Network

AltermanM@cofc.edu Alpha Kappa Alpha Sorority, Inc. Chapter Advisor Dena Magwood DENA_MAGWOOD@charleston.k12.sc.us Alpha Kappa Alpha Sorority, Inc. On-Campus Advisor Debbie Counts countsd@cofc.edu Alpha Phi Alpha Fraternity Inc. Chapter Advisor Dr. Rahn Ravenell Rravenell18@gmail.com Alpha Phi Alpha Fraternity

Young, Paul Thomas

437

Production of A=6,7 Nuclides in the Alpha + Alpha Reaction and Cosmic Ray Nucleosynthesis  

E-print Network

Cross sections for production of 6He, 6Li, 7Li, and 7Be in the alpha+alpha reaction were measured at bombarding energies of 159.3, 279.6, and 619.8 MeV, and are found to decrease rapidly with increasing energy. These cross sections are essential for the calculation of the rate of nucleosynthesis of the lithium isotopes in the cosmic rays and thereby play a key role in our understanding of the synthesis of Li, Be, and B. The results for 6Li differ significantly from the tabulated values commonly used in cosmic-ray production calculations and lead to lower production of 6Li.

David J. Mercer; Sam M. Austin; J. A. Brown; S. A. Danczyk; S. E. Hirzebruck; J. H. Kelley; T. Suomijarvi; D. A. Roberts; T. P Walker

2001-04-03

438

ON THE ORIGINS OF THE DIFFUSE H{alpha} EMISSION: IONIZED GAS OR DUST-SCATTERED H{alpha} HALOS?  

SciTech Connect

It is known that the diffuse H{alpha} emission outside of bright H II regions not only are very extended, but also can occur in distinct patches or filaments far from H II regions, and the line ratios of [S II] {lambda}6716/H{alpha} and [N II] {lambda}6583/H{alpha} observed far from bright H II regions are generally higher than those in the H II regions. These observations have been regarded as evidence against the dust-scattering origin of the diffuse H{alpha} emission (including other optical lines), and the effect of dust scattering has been neglected in studies on the diffuse H{alpha} emission. In this paper, we reexamine the arguments against dust scattering and find that the dust-scattering origin of the diffuse H{alpha} emission cannot be ruled out. As opposed to the previous contention, the expected dust-scattered H{alpha} halos surrounding H II regions are, in fact, in good agreement with the observed H{alpha} morphology. We calculate an extensive set of photoionization models by varying elemental abundances, ionizing stellar types, and clumpiness of the interstellar medium (ISM) and find that the observed line ratios of [S II]/H{alpha}, [N II]/H{alpha}, and He I {lambda}5876/H{alpha} in the diffuse ISM accord well with the dust-scattered halos around H II regions, which are photoionized by late O- and/or early B-type stars. We also demonstrate that the H{alpha} absorption feature in the underlying continuum from the dust-scattered starlight ({sup d}iffuse galactic light{sup )} and unresolved stars is able to substantially increase the [S II]/H{alpha} and [N II]/H{alpha} line ratios in the diffuse ISM.

Seon, Kwang-Il [Korea Astronomy and Space Science Institute, Daejeon 305-348 (Korea, Republic of); Witt, Adolf N., E-mail: kiseon@kasi.re.kr [Ritter Astrophysical Research Center, University of Toledo, Toledo, OH 43606 (United States)

2012-10-20

439

Diffusion des Metaux et Evolution Stellaire  

NASA Astrophysics Data System (ADS)

Nous presentons dans cette these des modeles d'evolution stellaire incorporant la diffusion microscopique de maniere consistante. Pour la premiere fois, on a calcule l'evolution d'etoiles en tenant compte en detail de l'impact des variations d'abondances sur leur structure. Nous utilisons des spectres monochromatiques pour chacun des elements les plus abondants dans un melange solaire pour recalculer l'opacite pour les abondances et les conditions locales dans l'interieur d'une etoile au cours de son evolution. Nos modeles montrent que la diffusion atomique des metaux a un effet important sur les opacites dan les etoiles de plus de 1.3Msolar ou l'abondance du fer et des autres elements du pic du fer varient substantiellement. Ces etoiles, sans rotation ou champ magnetique, sont proches des etoiles de type Fm-Am dans lesquelles on observe une legere surabondance d'elements du pic du fer en plus d'une sous-abondance de calcium, sous-abondance que l'on obtient egalement. Nous obtenons cependant des surabondances depassant un facteur 10 pour les etoiles de plus de 1.4Msolar ce qui suggere qu'il existe un ou plusieurs mecanismes limitant la diffusion microscopique. La surabondance du fer en surface cause une augmentation, qui peut atteindre un facteur sept, de l'opacite a la limite de la zone convective. Ceci cause un accroissement de la temperature effective et de la masse de la zone convective comparativement aux modeles n'incluant que la diffusion de l'helium. Il s'agit la du principal effet de la diffusion sur la structure interne de ces etoiles. La diffusions n'a pas d'influence sur l'evolution de coeur stellaire dans les etoiles significativement plus massives quie le Soleil. Nous avons verife que l'utilisation de modeles consistants avec diffusion n'apporte pas d'amelioration sensible aux modeles solaires. Les forces radiatives calculees a partir des spectres d'OPAL pour les elements du pic du fer representent une fraction importante de la gravite. On obtient des forces de 40% la gravite a la base de la zone convective. Ces forces radiatives sont assez grandes pour avoir un impact significatif sur les variations d'abondance de ces elements. Cet effet est neglige dans les modeles solaires publies. Nos modeles solaires montrent que les donnees du projet OPACITE pour le fer sont trop deficientes dans leur etat actuel pour pouvoir etre utilisees dans des calculs evolutifs. Nous confirmons que la diffusion doit etre prise en compte pour reproduire les donnes helioseismologiques. Nous discutons en detail de la manipulation des donnees monochromatiques. Il en ressort que les donnees d'OPAL sont superieures aux donnees tirees de OP. Les donnees de OP sont utiles pour les forces radiatives dans deux applications. Premierement pour determiner les corrections a apporter aux accelerations radiatives de OPAL pour tenir compte de la redistribution de l'impulsion lors de la photoionisation, puis parce que le sampling de OPAL perd de sa validite a basse temperature et pour les metaux tres peu abondants. Finalement nous avons calcule des modeles d'etoiles de population II de faible metallicite. Nous montrons dans un premier temps que la diffusion des metaux n'a pas d'effet significatif sur l'evolution de ces etoiles. Nous montrons egalement que l'incertitude sur l'age des amas globulaires associe a la diffusion est sous-estimee. Quoique la difference s'amenuise il existe toujours un desaccord avec l'age de l'Univers tel que determine a partir de la loi de Hubble.

Turcotte, Sylvain

440

Reduced Variability of Auditory Alpha Activity in Chronic Tinnitus  

PubMed Central

Subjective tinnitus is characterized by the conscious perception of a phantom sound which is usually more prominent under silence. Resting state recordings without any auditory stimulation demonstrated a decrease of cortical alpha activity in temporal areas of subjects with an ongoing tinnitus perception. This is often interpreted as an indicator for enhanced excitability of the auditory cortex in tinnitus. In this study we want to further investigate this effect by analysing the moment-to-moment variability of the alpha activity in temporal areas. Magnetoencephalographic resting state recordings of 21 tinnitus subjects and 21 healthy controls were analysed with respect to the mean and the variability of spectral power in the alpha frequency band over temporal areas. A significant decrease of auditory alpha activity was detected for the low alpha frequency band (8–10?Hz) but not for the upper alpha band (10–12?Hz). Furthermore, we found a significant decrease of alpha variability for the tinnitus group. This result was significant for the lower alpha frequency range and not significant for the upper alpha frequencies. Tinnitus subjects with a longer history of tinnitus showed less variability of their auditory alpha activity which might be an indicator for reduced adaptability of the auditory cortex in chronic tinnitus. PMID:24967106

Schecklmann, Martin; Kreuzer, Peter M.; Vielsmeier, Veronika; Poeppl, Timm B.; Langguth, Berthold

2014-01-01

441

The Navier-Stokes-alpha model of fluid turbulence  

E-print Network

We review the properties of the nonlinearly dispersive Navier-Stokes-alpha (NS-alpha) model of incompressible fluid turbulence -- also called the viscous Camassa-Holm equations and the LANS equations in the literature. We first re-derive the NS-alpha model by filtering the velocity of the fluid loop in Kelvin's circulation theorem for the Navier-Stokes equations. Then we show that this filtering causes the wavenumber spectrum of the translational kinetic energy for the NS-alpha model to roll off as k^{-3} for k \\alpha > 1 in three dimensions, instead of continuing along the slower Kolmogorov scaling law, k^{-5/3}, that it follows for k \\alpha < 1. This rolloff at higher wavenumbers shortens the inertial range for the NS-alpha model and thereby makes it more computable. We also explain how the NS-alpha model is related to large eddy simulation (LES) turbulence modeling and to the stress tensor for second-grade fluids. We close by surveying recent results in the literature for the NS-alpha model and its inviscid limit (the Euler-alpha model).

C. Foias; D. D. Holm; E. S. Titi

2001-03-23

442

ANAL YSE DES STRUCTURES MAGNETIQUES ET THEORIE DES ON TWO CLASSIFICATIONS OF MAGNETIC STRUCTURES  

E-print Network

ANAL YSE DES STRUCTURES MAGNETIQUES ET THEORIE DES GRBUPES ON TWO CLASSIFICATIONS OF MAGNETIC- fication. Abstract. -A general formulation of the classification (called here C2) of magnetic structures, in a precisely defined mathematical sense, equivalent to the classification(called here Cl') based on the use

Boyer, Edmond

443

Contrle pour des systmes gouverns par des quations aux drives partielles  

E-print Network

à vapeurs (J. Watt en 1769), etc Voir l'article de James Clerk Maxwell dont l'article On governors), régulation de vitesse des machines à vapeurs (J. Watt en 1769), etc Voir l'article de James Clerk Maxwell vitesse des machines à vapeurs (J. Watt en 1769), etc Voir l'article de James Clerk Maxwell dont l

Jeanjean, Louis

444

Contribution du gros intestin la digestion des glucides et des matires azotes chez le monogastrique omnivore  

E-print Network

Contribution du gros intestin à la digestion des glucides et des matières azotées chez le-en-Josas (France). Summary. Contribution of the large intestine to the digestion of carbohydrates and proteins in omnivorous simple-stomached animals. Owing to its special situation in relation to the rest of the digestive

Paris-Sud XI, Université de

445

EXTRACTION DE CONNAISSANCES PARTIR DES DONNEES ET DES TEXTES (ECD ET ECT "DATA & TEXT MINING")  

E-print Network

1 EXTRACTION DE CONNAISSANCES � PARTIR DES DONNEES ET DES TEXTES (ECD ET ECT "DATA & TEXT MINING'Extraction de Connaissances à partir de Textes (ECT, "Text Mining") comme un descendant direct de l'Extraction de Connaissances à partir de Données (ECD, "Data Mining"). Le point fondamental qui distingue ces

Spagnolo, Filippo

446

Table des mati`eres Cours IX. Th'eories cohomologiques des sch'emas ...................... 1  

E-print Network

sch'emas ...................... 1 IX.1. Axiomatique des cohomologies en g'eom'etrie alg'ef'erences ..............................................................* *...... 12 COURS IX TH'EORIES COHOMOLOGIQUES DES SCH'EMAS* *rtains type de sch'emas. On fixe un sch'ema de base S et on consid`ere S une sous-cat'egorie d* *e la

Deglise, Frédéric

447

//. --LES PERFORMANCES DES LASERS. STABILIT DE FRQUENCE ET PURET SPECTRALE DES LASERS  

E-print Network

and resolving power. Measurement tech- //. -- LES PERFORMANCES DES LASERS. STABILIT� DE FR�QUENCE ET PURET� SPECTRALE DES LASERS F laser peut s'apprécier selon deux critères différents : -- stabilité de fréquence, traduisant le

Boyer, Edmond

448

[TALAF-O.2] Projet des corpus crits des langues manding : le bambara, le maninka1  

E-print Network

[TALAF-O.2] 109 Projet des corpus écrits des langues manding : le bambara, le maninka1 Valentin textes en langues mandingues a démarré à St. Petersbourg en 2009. Aujourd'hui, il est effectué par une of electronic corpora for Manding languages was launched in St. Petersburg in 2009. By now, it is carried out

449

N d'ordre 1109 Interactions tritrophiques entre des Brassicaces, des  

E-print Network

'interprétation des données de génétique, et enfin Lucie Mieuzet pour l'apprentissage des techniques de génotypages Henri Carpentier pour le support logistique en serre et sur le terrain. Eric pour les réparations

Paris-Sud XI, Université de

450

Comptes Rendus des JNC 16 Toulouse 2009 Comportement mcanique de textiles tricots techniques pour des  

E-print Network

Comptes Rendus des JNC 16 Toulouse 2009 Comportement mécanique de textiles tricotés techniques pour des applications composites Mechanical behaviour of technical knitted fabrics for composite-mail : lbalea@enstimac.fr, dusserre@enstimac.fr, bernhart@enstimac.fr 2 : Textile Aéro Tarn 81360 Montredon

Paris-Sud XI, Université de

451

L'analyse des relations dynamiques entre variables : une application au taux du marché monétaire français  

Microsoft Academic Search

[fre] La détection des relations dynamiques existant entre des variables pose un problème important en économie. Des procédures statistiques, fondées sur l'étude des résidus issus de filtres ARIMA de Box et Jenkins, ont été récemment développées. Ce texte présente ces méthodes statistiques : détermination des filtres ARIMA, étude des corrélogrammes entre résidus, estimation de fonctions de transfert. Celles-ci sont ensuite

Gilbert Colletaz; William Marois

1981-01-01

452

{alpha} decay chains from element 113  

SciTech Connect

Theoretical estimates of {alpha}-decay half-lives of several nuclei in the decay from element 113 are presented. Calculations in a WKB framework using DDM3Y interaction and experimental Q-values are in good agreement with the experimental data. Half-life calculations are found to be quite sensitive to the Q-values and angular momentum transfers. Calculated decay lifetime decreases, owing to more penetrability as well as thinner barrier, as Q-value increases. Deviations to this predominant behavior observed in some recent experimental data may be attributed to nonzero spin-parities in some cases.

Chowdhury, P. Roy [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700 064 (India); Basu, D. N. [Variable Energy Cyclotron Centres, 1/AF Bidhan Nagar, Kolkata 700 064 (India); Samanta, C. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700 064 (India); Physics Department, Virginia Commonwealth University, Richmond, Virginia 23284-2000 (United States)

2007-04-15

453

Synthesis of alpha-amino acids  

DOEpatents

A method for synthesizing alpha amino acids proceding through novel intermediates of the formulas: R.sub.1 R.sub.2 C(OSOCl)CN, R.sub.1 R.sub.2 C(Cl)CN and [R.sub.1 R.sub.2 C(CN)O].sub.2 SO wherein R.sub.1 and R.sub.2 are each selected from hydrogen monovalent substituted and unsubstituted hydrocarbon radicals of 1 to 10 carbon atoms. The use of these intermediates allows the synthesis steps to be exothermic and results in an overall synthesis method which is faster than the snythesis methods of the prior art.

Davis, Jr., Jefferson W. (San Francisco, CA)

1983-01-01

454

Synthesis of alpha-amino acids  

DOEpatents

A method for synthesizing alpha amino acids proceeding through novel intermediates of the formulas: R.sub.1 R.sub.2 C(OSOCl)CN, R.sub.1 R.sub.2 C(Cl)CN and [R.sub.1 R.sub.2 C(CN)O].sub.2 SO wherein R.sub.1 and R.sub.2 are each selected from hydrogen monovalent substituted and unsubstituted hydrocarbon radicals of 1 to 12 carbon atoms. The use of these intermediates allows the synthesis steps to be exothermic and results in an overall synthesis method which is faster than the synthesis methods of the prior art.

Davis, Jr., Jefferson W. (San Francisco, CA)

1983-01-01

455

Synthesis of alpha-amino acids  

DOEpatents

A method for synthesizing alpha amino acids proceding through novel intermediates of the formulas: R.sub.1 R.sub.2 C(OSOCl)CN, R.sub.1 R.sub.2 C(Cl)CN and [R.sub.1 R.sub.2 C(CN)O].sub.2 SO wherein R.sub.1 and R.sub.2 are each selected from hydrogen monovalent substituted and unsubstituted hydrocarbon radicals of 1 to 12 carbon atoms. The use of these intermediates allows the synthesis steps to be exothermic and results in an overall synthesis method which is faster than the synthesis methods of the prior art.

Davis, Jr., Jefferson W. (San Francisco, CA)

1983-01-01

456

Alpha resonant scattering for astrophysical reaction studies  

NASA Astrophysics Data System (ADS)

Several alpha-induced astrophysical reactions have been studied at CRIB (CNS Radioactive Ion Beam separator), which is a low-energy RI beam separator at Center for Nuclear Study (CNS) of the University of Tokyo. One of the methods to study them is the ? resonant scattering using the thick-target method in inverse kinematics. Among the recent studies at CRIB, the measurement of 7Be+? resonant scattering is discussed. Based on the result of the experiment, we evaluated the contributions of high-lying resonances for the 7Be(?,?) reaction, and proposed a new cluster band in 11C.

Yamaguchi, H.; Kahl, D.; Nakao, T.; Wakabayashi, Y.; Kubano, S.; Hashimoto, T.; Hayakawa, S.; Kawabata, T.; Iwasa, N.; Teranishi, T.; Kwon, Y. K.; Binh, D. N.; Khiem, L. H.; Duy, N. G.

2014-05-01

457

Alpha Channeling in a Rotating Plasma  

SciTech Connect

The wave-particle ?-channeling effect is generalized to include rotating plasma. Specifically, radio frequency waves can resonate with ? particles in a mirror machine with E × B rotation to diffuse the ? particles along constrained paths in phase space. Of major interest is that the ?-particle energy, in addition to amplifying the RF waves, can directly enhance the rotation energy which in turn provides additional plasma confinement in centrifugal fusion reactors. An ancillary benefit is the rapid removal of alpha particles, which increases the fusion reactivity.

Abraham J. Fetterman and Nathaniel J. Fisch

2008-09-23

458

Synthesis of alpha-cyclopropyl-beta-homoprolines.  

PubMed

1-(2-Pyrrolidinyl)cyclopropanecarboxylic acids (alpha-cyclopropyl-beta-homoprolines) were prepared by 1,3-dipolar cycloadditions of cyclic nitrones onto bicyclopropylidene followed by trifluoroacetic acid induced thermal fragmentative rearrangement. With the use of enantiopure pyrroline N-oxides derived from easily available chiral pool molecules, beta-homoprolines were formed with high stereocontrol. The incorporation of one of these new cyclic beta-amino acids into a simple tripeptide was also evaluated. In particular, the sterically hindered nitrogen atom of the highly substituted pyrrolidine 30 was smoothly acylated through the intermediate formation of a mixed anhydride. PMID:19413279

Cordero, Franca M; Salvati, Maria; Vurchio, Carolina; de Meijere, Armin; Brandi, Alberto

2009-06-01

459

Electron shell and the alpha-decay  

E-print Network

The ratio of the alpha-decay widths of a bare nucleus and the related atom is calculated. Both the change of the form and thus the penetrability of the potential barrier and the effect of reflection in the classically-allowed region appearing due to the electron shell are taken into account in the calculations of this ratio. The contribution of each of these two effects is of one and the same order of magnitude. For long-lived radioactive samples the values of the total effect turn out to be somewhat below 1 percent.

Sergey Yu. Igashov; Yury M. Tchuvil'sky

2012-12-03

460

Alpha resonant scattering for astrophysical reaction studies  

SciTech Connect

Several alpha-induced astrophysical reactions have been studied at CRIB (CNS Radioactive Ion Beam separator), which is a low-energy RI beam separator at Center for Nuclear Study (CNS) of the University of Tokyo. One of the methods to study them is the ? resonant scattering using the thick-target method in inverse kinematics. Among the recent studies at CRIB, the measurement of {sup 7}Be+? resonant scattering is discussed. Based on the result of the experiment, we evaluated the contributions of high-lying resonances for the {sup 7}Be(?,?) reaction, and proposed a new cluster band in {sup 11}C.

Yamaguchi, H.; Kahl, D.; Nakao, T. [Center for Nuclear Study (CNS), University of Tokyo, RIKEN campus, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Wakabayashi, Y.; Kubano, S. [The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Hashimoto, T. [Research Center for Nuclear Physics (RCNP), Osaka University, 10-1 Mihogaoka, Ibaraki, Osaka 567-0047 (Japan); Hayakawa, S. [Istituto Nazionale Fisica Nucleare - Laboratori Nazionali del Sud (INFN-LNS), Via S. Sofia 62, 95125 Catania (Italy); Kawabata, T. [Department of Physics, Kyoto University, Kita-Shirakawa, Kyoto 606-8502 (Japan); Iwasa, N. [Department of Physics, Tohoku University, Aoba, Sendai, Miyagi 980-8578 (Japan); Teranishi, T. [Department of Physics, Kyushu University, 6-10-1 Hakozaki, Fukuoka 812-8581 (Japan); Kwon, Y. K. [Institute for Basic Science, 70, Yuseong-daero 1689-gil, Yuseong-gu, Daejeon 305-811 (Korea, Republic of); Binh, D. N. [30 MeV Cyclotron Center, Tran Hung Dao Hospital, Hoan Kiem District, Hanoi (Viet Nam); Khiem, L. H.; Duy, N. G. [Institute of Physics, Vietnam Academy of Science and Technology, 18 Hong Quoc Viet, Nghia do, Hanoi (Viet Nam)

2014-05-02

461

Voids in the Ly-alpha forest  

NASA Technical Reports Server (NTRS)

The general issue of using the Ly-alpha absorbers in quasar spectra as tracers of the large-scale matter distribution is discussed, emphasizing complications due to evolutionary effects and line blending. Then, a novel method of statistical analysis of the line data appropriate for studying large-scale structure is described. This method circumvents the problem of line blending by truncating the interval distribution at the low end. It also explicitly takes z-dependent effects into account. As an example, the method is applied to an 18-quasar spectrum sample of 417 lines.

Duncan, Robert C.; Ostriker, Jeremiah P.; Bajtlik, Stanislaw

1989-01-01

462

Molecular Dynamics Simulations of Alpha-synuclein  

NASA Astrophysics Data System (ADS)

We investigate the conformational dynamics of single alpha-synuclein proteins, which have been implicated in amyloid diseases such as Parkinson's and Alzheimer's disease, in solution using unconstrained and constrained all-atom, explicit solvent molecular dynamics simulations. The constraints on inter-residue separations are obtained from our single-molecule FRET measurements of eleven FRET pairs that span the protein. By comparing the simulation data satisfying different combinations of FRET constraints, we are able to identify those constraints that are most important in determining the radius of gyration and key features of the contact map of the protein.

Sammalkorpi, Maria; Schreck, Carl; Nath, Abhinav; Dewitt, David; Rhoades, Elizabeth; O'Hern, Corey

2011-03-01

463

The ALPHA Lab at UC Berkeley  

NSDL National Science Digital Library

The Alpha Lab at the University of California at Berkeley researches and develops robotics systems for high-precision manufacturing. Specifically, it combines mathematical algorithms and industrial automation to build low-cost, reliable tools for "feeding, fixturing and grasping." The projects section of the lab's Web site describes a number of experiments and model implementations for robotics operation. Many of these have Java applets that demonstrate the principles involved in handling differently shaped objects. There are also discussions of various projects in computational physiology and Internet telerobotics. The lab's director has many of his publications available online.

464

Lexical access and evoked traveling alpha waves  

PubMed Central

Retrieval from semantic memory is usually considered within a time window around 300–600 ms. Here we suggest that lexical access already occurs at around 100 ms. This interpretation is based on the finding that semantically rich and frequent words exhibit a significantly shorter topographical latency difference between the site with the shortest P1 latency (leading site) and that with the longest P1 latency (trailing site). This latency difference can be described in terms of an evoked traveling alpha wave as was already shown in earlier studies. PMID:24486978

Zauner, Andrea; Gruber, Walter; Himmelstoß, Nicole Alexandra; Lechinger, Julia; Klimesch, Wolfgang

2014-01-01

465

Characterization of the alpha-gamma and alpha-beta complex: evidence for an in vivo functional role of alpha-crystallin as a molecular chaperone  

NASA Technical Reports Server (NTRS)

Previous studies have demonstrated that in vitro, alpha-crystallin can protect other lens proteins against extensive denaturation and aggregation. The mechanism of this protection involves preferential binding of the partially denatured protein to a central region of the native alpha-crystallin complex. To test whether a similar phenomenon might occur in vivo, a high molecular weight aggregate (HMWA) fraction was isolated from the aged bovine lens. Negative staining of this preparation revealed the presence of particles of 13-14 nm diameter, characteristic of alpha-crystallin. Immunolocalization of the same particles using antiserum specific for gamma- and beta-crystallins demonstrated preferential binding of these crystallins to the central region of the alpha-crystallin complex. Together, these results provide evidence that in the intact lens, the alpha-crystallins are functionally important molecular chaperones.

Boyle, D.; Takemoto, L.; Spooner, B. S. (Principal Investigator)

1994-01-01

466

Developpement des betons semi autoplacants a rheologie adaptee pour des infrastructures  

NASA Astrophysics Data System (ADS)

Au cours des dernières décennies, les infrastructures canadiennes et québécoises comportent plusieurs structures en béton armé présentant des problèmes de durabilité dus aux conditions climatiques sévères, à la mauvaise conception des structures, à la qualité des matériaux, aux types des bétons choisis, aux systèmes de construction ou à l'existence d'événements incontrôlables. En ce qui concerne le choix du béton pour la construction des infrastructures, une vaste gamme de béton divisée en deux principaux types peut être utilisée: le béton conventionnel vibré (BCV) et le béton autoplaçant (BAP). Dans le cas d'un BCV, la consolidation inadéquate par vibration a été un problème récurrent, occasionnant des dommages structuraux. Ceci a conduit à une réduction de la durabilité et à une augmentation du coût d'entretien et de réparation des infrastructures. Rien que l'utilisation d'un BAP a des avantages tels que l'élimination de la vibration, la réduction des coûts de main d'oeuvre et l'amélioration de la qualité des structures, néanmoins, le coût initial d'un BAP par rapport à un BCV ne permet pas encore de généraliser son utilisation dans l'industrie de la construction. Ce mémoire présente la conception d'une nouvelle gamme de béton semi-autoplaçant pour la construction des infrastructures (BSAP-I) exigeant une vibration minimale. Il s'agit de trouver un équilibre optimal entre la rhéologie et le coût initial du nouveau béton pour conférer une bonne performance structurale et économique aux structures. Le programme expérimental établi a premièrement permis d'évaluer la faisabilité d'utilisation des BSAP-I pour la mise en place des piliers d'une infrastructure de pont à Sherbrooke. En plus, l'utilisation d'un plan d'expériences a permis l'évaluation de trois paramètres de formulation sur les propriétés des mélanges de BSAP-I à l'état frais et durci. Finalement, l'évaluation de la performance des BSAP-I optimisés à travers une caractérisation complète des propriétés mécaniques et de la durabilité a été réalisée. A la suite de cette étude, les résultats obtenus nous permettent de conclure que : (1) L'utilisation d'un BSAP-I avec un gros granulat de 5 - 14 mm, des rapports E/L = 0,37 et S/G = 0,52 et une teneur en air de 6 à 9% a été possible en conférant un équilibre optimal fluidité / stabilité à l'état frais, ainsi qu'un niveau de thixotropie adéquate au chantier permettant d'optimiser la conception du coffrage des piliers de pont et de conférer des qualités de surfaces très acceptables de ces infrastructures. (2) La méthode adaptée pour l'essai L-Box contenant 2 barres et une vibration de 5 secondes a permis de bien caractériser la capacité de remplissage d'un BSAP-I. (3) L'utilisation d'un plan factoriel 23 a permis d'obtenir des modèles statistiques fiables, capables de prédire les propriétés rhéologiques à l'état frais et les résistances en compression des BSAP-I avec des dosages en liant entre 370 et 420 kg/m3, des rapports E/L entre 0,34 et 0,40 et S/G entre 0,47 et 0,53. (4) Des mesures de vitesse d'écoulement T40 d'un BSAP-I sont très semblables à celles d'un BAP. En plus, des valeurs T40 montrent une bonne corrélation linéaire avec celles de T400 mesurés dans la boîte L-Box. (5) À la frontière du BAP et du BCV, une bande rhéologique possédant un ?0 entre 30 et 320 Pa et un ? entre 10 et 140 Pa.s a été trouvée pour la conception optimale des BSAP-I. (6) Les BSAP-I optimisés ont également conféré une très bonne performance à l'état frais, en permettant maintenir un bon équilibre entre la rhéologie et la stabilité dans le temps, lorsqu'on utilise une énergie de vibration minimale pour amorcer son écoulement. (7) À l'état durci Les BSAP-I ont conféré une bonne performance présentant des résistances mécaniques élevées et des niveaux négligeables de pénétration aux ions chlores, de perte de masse par écaillage et des attaques par le gel/dégel. (8) L'utilisation des cim

Sotomayor Cruz, Cristian Daniel

467

Alpha-crystallin: molecular chaperone and protein surfactant.  

PubMed

Bovine lens alpha-crystallin has recently been shown to function as a molecular chaperone by stabilizing proteins against heat denaturation (Horwitz, J. (1992) Proc. Natl. Acad. Sci. USA, 89, 10449-10453). An investigation, using a variety of physico-chemical methods, is presented into the mechanism of stabilization. alpha-Crystallin exhibits properties of a surfactant. Firstly, a plot of conductivity of alpha-crystallin versus concentration shows a distinct inflection in its profile, i.e., a critical micelle concentration (cmc), over a concentration range from 0.15 to 0.17 mM. Gel chromatographic and 1H-NMR spectroscopic studies spanning the cmc indicate no change in the aggregated state of alpha-crystallin implying that a change in conformation of the aggregate occurs at the cmc. Secondly, spectrophotometric studies of the rate of heat-induced aggregation and precipitation of alcohol dehydrogenase (ADH), beta L- and gamma-crystallin in the presence of alpha-crystallin and a variety of synthetic surfactants show that stabilization against precipitation results from hydrophobic interactions with alpha-crystallin and monomeric anionic surfactants. Per mole of subunit or monomer, alpha-crystallin is the most efficient at stabilization. alpha-Crystallin, however, does not preserve the activity of ADH after heating. After heat inactivation, gel permeation HPLC indicates that ADH and alpha-crystallin form a high molecular weight aggregate. Similar results are obtained following incubation of beta L- and gamma-crystallin with alpha-crystallin. 1H-NMR spectroscopy of mixtures of alpha- and beta L-crystallin, in their native states, reveals that the C-terminus of beta B2-crystallin is involved in interaction with alpha-crystallin. In the case of gamma- and alpha-crystallin mixtures, a specific interaction occurs between alpha-crystallin and the C-terminal region of gamma B-crystallin, an area which is known from the crystal structure to be relatively hydrophobic and to be involved in intermolecular interactions. The short, flexible C-terminal extensions of alpha-crystallin are not involved in specific interactions with these proteins. It is concluded that alpha-crystallin interacts with native proteins in a weak manner. Once a protein has become denatured, however, the soluble complex with alpha-crystallin cannot be readily dissociated. In the aging lens this finding may have relevance to the formation of high molecular weight crystallin aggregates. PMID:8142460

Carver, J A; Aquilina, J A; Cooper, P G; Williams, G A; Truscott, R J

1994-02-16

468

Robustness of truncated alpha-Omega dynamos with a dynamic alpha  

E-print Network

In a recent work (Covas et al. 1997), the behaviour and the robustness of truncated $\\alpha\\Omega$ dynamos with a dynamic $\\alpha$ were studied with respect to a number of changes in the driving term of the dynamic $\\alpha$ equation, which was considered previously by Schmalz and Stix (1991) to be of the form $\\sim A_{\\phi}B_{\\phi}$. Here we review and extend our previous work and consider the effect of adding a quadratic quenching term of the form $\\alpha|B|^2$. We find that, as before, such a change can have significant effects on the dynamics of the related truncated systems. We also find intervals of (negative) dynamo numbers, in the system considered by Schmalz and Stix (1991), for which there is sensitivity with respect to small changes in the dynamo number and the initial conditions, similar to what was found in our previous work. This latter behaviour may be of importance in producing the intermittent type of behaviour observed in the sun.

Eurico Covas; Andrew Tworkowski; Reza Tavakol; Axel Brandenburg

1997-08-11

469

Aqueous chemical growth of alpha-Fe2O3-alpha-Cr203 nanocompositethin films  

SciTech Connect

We are reporting here on the inexpensive fabrication and optical properties of an iron(III) oxide chromium(III) oxide nanocomposite thin film of corundum crystal structure. Its novel and unique-designed architecture consists of uniformed, well-defined and oriented nanorods of Hematite (alpha-Fe2O3) of 50 nm in diameter and 500nm in length and homogeneously distributed nonaggregated monodisperse spherical nanoparticles of Eskolaite (alpha-Cr2O3) of 250 nm in diameter. This alpha-Fe2O3 alpha-Cr2O3 nanocomposite thin film is obtained by growing, directly onto transparent polycrystalline conducting substrate, an oriented layer of hematite nanorods and growing subsequently, the eskolaite layer. The synthesis is carried out by a template-free, low-temperature, multilayer thin film coating process using aqueous solution of metal salts as precursors. Almost 100 percent of the light is absorbed by the composite film between 300 and 525 nm and 40 percent at 800 nm which yields great expectations as photoanode materials for photovoltaic cells and photocatalytic devices.

Vayssieres, Lionel; Guo, Jinghua; Nordgren, Joseph

2001-06-30

470

An alpha particle instrument with alpha, proton, and X-ray modes for planetary chemical analyses  

NASA Technical Reports Server (NTRS)

The interaction of alpha particles with matter is employed in a compact instrument that could provide rather complete in-situ chemical analyses of surfaces and thin atmospheres of extraterrestrial bodies. The instrument is a miniaturized and improved version of the Surveyor lunar instrument. The backscattering of alpha particles and (alpha, p) reactions provide analytical data on the light elements (carbon-iron). An X-ray mode that detects the photons produced by the alpha sources provides sensitivity and resolution for the chemical elements heavier than about silicon. The X-rays are detected by semiconductor detectors having a resolution between 150 and 250 eV at 5.9 keV. Such an instrument can identify and determine with good accuracy 99 percent of the atoms (except hydrogen) in rocks. For many trace elements, the detecting sensitivity is a few ppm. Auxiliary sources could be used to enhance the sensitivities for elements of special interest. The instrument could probably withstand the acceleration involved in semi-hard landings.

Economou, T. E.; Turkevich, A. L.

1976-01-01

471

Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor.  

PubMed

Helicobacter pylori vacuolating cytotoxin, VacA, induces vacuolation, mitochondrial damage, cytochrome c release, and apoptosis of gastric epithelial cells. To detect gastric proteins that serve as VacA receptors, we used VacA co-immunoprecipitation techniques following biotinylation of the cell surface and identified p250, a receptor-like protein-tyrosine phosphatase beta (RPTP beta) as a VacA-binding protein (Yahiro, K., Niidome, T., Kimura, M., Hatakeyama, T., Aoyagi, H., Kurazono, H., Imagawa, K., Wada, A., Moss, J., and Hirayama, T. (1999) J. Biol. Chem. 274, 36693-36699). VacA causes vacuolation of G401 cells, a human kidney tumor cell line, although they do not express RPTP beta. By co-immunoprecipitation with VacA, we identified p140 as a potential receptor in those cells. p140 purified by chromatography on a peanut agglutinin affinity matrix contained internal amino acid sequences of RGEENTDYVNASFIDGYRQK and AEGILDVFQTVK, which are identical to those in RPTP alpha. The peptide mass fingerprinting of p140 by time of flight-MS analysis also supported this identification. Treatment of G401 cells with RPTP alpha-morpholino antisense oligonucleotide before exposure to toxin inhibited vacuolation. These data suggest that RPTP alpha acts as a receptor for VacA in G401 cells. Thus, two receptor tyrosine phosphatases, RPTP alpha and RPTP beta, serve as VacA receptors. PMID:12626515

Yahiro, Kinnosuke; Wada, Akihiro; Nakayama, Masaaki; Kimura, Takahiro; Ogushi, Ken-ichi; Niidome, Takuro; Aoyagi, Haruhiko; Yoshino, Ken-ichi; Yonezawa, Kazuyoshi; Moss, Joel; Hirayama, Toshiya

2003-05-23

472

A Precise Determination of $\\alpha_s$ from the C-parameter Distribution  

E-print Network

We present a global fit for $\\alpha_s(m_Z)$, analyzing the available C-parameter data measured at center-of-mass energies between $Q=35$ and $207$ GeV. The experimental data is compared to a N$^3$LL$^\\prime$ + $\\mathcal{O}(\\alpha_s^3)$ + $\\Omega_1$ theoretical prediction (up to the missing 4-loop cusp anomalous dimension), which includes power corrections coming from a field theoretical nonperturbative soft function. The dominant hadronic parameter is its first moment $\\Omega_1$, which is defined in a scheme which eliminates the $\\mathcal{O}(\\Lambda_{\\rm QCD})$ renormalon ambiguity. The resummation region plays a dominant role in the C-parameter spectrum, and in this region a fit for $\\alpha_s(m_Z)$ and $\\Omega_1$ is sufficient. We find $\\alpha_s(m_Z)=0.1123\\pm 0.0015$ and $\\Omega_1=0.421\\pm 0.063\\,{\\rm GeV}$ with $\\chi^2/\\rm{dof}=0.988$ for $404$ bins of data. These results agree with the prediction of universality for $\\Omega_1$ between thrust and C-parameter within 1-$\\sigma$.

Hoang, André H; Mateu, Vicent; Stewart, Iain W

2015-01-01

473

Comparison of Limulus alpha-macroglobulin with human alpha2-macroglobulin: thiol ester characterization, subunit organization, and conformational change.  

PubMed

The properties of the thiol ester-containing alpha-macroglobulin (alphaM) from the horseshoe crab (Limulus polyphemus) have been compared with those of the human analogue (alpha2M). Thiol ester accessibility was more restricted in Limulus alphaM than in human alpha2M. Fluorescent probes attached to the thiol ester cysteine indicated very similar local environments in the cleaved state of the two alphaMs. The separation between the two thiol ester cysteines in the cleaved state, determined by fluorescence resonance energy transfer, was also very similar for the two alphaMs. Differences were found in the oligomerization state and conformational changes of the two proteins. Whereas human alpha2M appears to be exclusively a dimer of dimers, Limulus alphaM can exist in both tetrameric and dimeric forms, although with marked preference for the dimer. Conformational change within a dimeric trapping unit, monitored by 6-(p-toluidino)-2-napthalene-sulfonic acid fluorescence change, showed that each monomer of the Limulus alphaM dimer appears to change conformation independently, whereas human alpha2M requires both thiol esters within a functional unit to be cleaved before the conformational change occurs. Taken together, these findings indicate that, whereas individual thiol esters in both types of alphaM are similar in properties, differences in subunit-subunit interaction result both in differences in state of oligomerization and in cooperativity of conformational change, which may reflect a fundamentally different organization of the subunits within a dimer in the two alphaMs. PMID:9016813

Bowen, M E; Armstrong, P B; Quigley, J P; Gettins, P G

1997-01-15

474

Technical Equivalency Documentation for a New Alpha Spectroscopy System  

SciTech Connect

The response of a new Canberra{trademark} Alpha Analyst (Chamber No.'s 101-124) used by the Hazards Control, Radiation Safety Section, WBC/Spectroscopy Team has been studied with respect to an existing Canberra system. The existing Canberra system consists of thirty six Model 7401 alpha spectrometry chambers (Chamber No.'s 1-36) and has been DOELAP qualified for the routine Alpha Spectroscopy program used in LLNL's in vitro bioassay program. The new Alpha Analyst system is an automated system that is controlled by the same software and computer system as that used for the existing Canberra system. This document compares results from the existing Alpha System with the newer Alpha Analyst system.

Hickman, D P; Fisher, S K; Zeman, R A; Hann, P R

2005-04-05

475

H alpha survey of late-type active binaries  

NASA Astrophysics Data System (ADS)

H alpha spectrophotometry of 33, chromospherically active, close binaries (mostly RS CVn), obtained at the Catania Astrophysical Observatory, is reported. We define the H alpha emission component for each observed system as the difference between the observed spectrum and a synthetic 'composite' spectrum made up by the weighted sum of spectra of non active stars similar in spectral types to the components of the system. This procedure allows us to detect an emission component in the H alpha core, also for some systems which apparently present a normal H alpha absorption profile. We investigate the possible correlation between this net H alpha surface flux and luminosity as a function of (B-V) and the rotational period. In particular we find that the net H alpha surface flux correlates moderately well with the rotational period, in agreement with previous results. The trend of increasing activity with decreasing rotational period can be described either by a power law or an exponential law.

Frasca, A.; Catalano, S.

1994-04-01

476

The role of alpha oscillations for illusory perception.  

PubMed

Alpha oscillations are a prominent electrophysiological signal measured across a wide range of species and cortical and subcortical sites. Alpha oscillations have been viewed for a long time as an "idling" rhythm, purely reflecting inactive sites. Despite earlier evidence from neurophysiology, awareness that alpha oscillations can substantially influence perception and behavior has grown only recently in cognitive neuroscience. Evidence for an active role of alpha for perception comes mainly from several visual, near-threshold experiments. In the current review, we extend this view by summarizing studies showing how alpha-defined brain states relate to illusory perception, i.e. cases of perceptual reports that are not "objectively" verifiable by distinct stimuli or stimulus features. These studies demonstrate that ongoing or prestimulus alpha oscillations substantially influence the perception of auditory, visual or multisensory illusions. PMID:24931795

Lange, Joachim; Keil, Julian; Schnitzler, Alfons; van Dijk, Hanneke; Weisz, Nathan

2014-09-01

477

The role of alpha oscillations for illusory perception  

PubMed Central

Alpha oscillations are a prominent electrophysiological signal measured across a wide range of species and cortical and subcortical sites. Alpha oscillations have been viewed for a long time as an “idling” rhythm, purely reflecting inactive sites. Despite earlier evidence from neurophysiology, awareness that alpha oscillations can substantially influence perception and behavior has grown only recently in cognitive neuroscience. Evidence for an active role of alpha for perception comes mainly from several visual, near-threshold experiments. In the current review, we extend this view by summarizing studies showing how alpha-defined brain states relate to illusory perception, i.e. cases of perceptual reports that are not “objectively” verifiable by distinct stimuli or stimulus features. These studies demonstrate that ongoing or prestimulus alpha oscillations substantially influence the perception of auditory, visual or multisensory illusions. PMID:24931795

Lange, Joachim; Keil, Julian; Schnitzler, Alfons; van Dijk, Hanneke; Weisz, Nathan

2014-01-01

478

Zadaxin (thymosin alpha1) for the treatment of viral hepatitis.  

PubMed

Zadaxin (thymosin alpha1; Talpha1) is a synthetic 28 amino acid peptide with multiple biological activities primarily directed towards immune response enhancement. Since the immune system plays a critical role in the control and elimination of viral hepatitis infection, immune active agents such as Talpha1 are of potential therapeutic value. In clinical trials, Talpha1 has been shown to be effective in chronic hepatitis B, both asmonotherapy and in combination with interferon-alpha (IFN-alpha). In chronic hepatitis C it was effective in combination with IFN-alpha. Since Talpha1 has few side-effects and is effective in combination with IFN-alpha, future clinical trials should evaluate the potential of Talpha1 to enhance the activity of antivirals such as IFN-alpha, ribavirin and lamivudine as viral hepatitis therapy. PMID:15992078

Naylor, P H

1999-03-01

479

PhET Simulation: Alpha Decay  

NSDL National Science Digital Library

This resource simulates the process of alpha decay, a type of radioactive decay in which an atomic nucleus emits an alpha particle. A number of different radioisotopes will undergo this type of decay; this web page simulates the Polonium-211 atom. Users can watch a single atom decay or work with a "Bucket O' Polonium" to view a pattern of decay. Editor's Note: Radioactive decay happens when an atomic nucleus of an unstable atom loses energy by emitting ionizing radiation. If you take a sample of a particular radionuclide, the half-life is the time it takes for half the atoms to decay. The Bucket O' Polomium" activity could be invaluable to help students understand the concept of half-life. They can observe 100 virtual polonium-211 atoms in the process of decay. Pause the action every 1/2 second to get a feel for the math associated with radioactive decay. Simple enough for grades 7-8, but can be adapted for AP Physics as well. See Related Materials for a link to a student guide specifically developed by the PhET team for use with this simulation.

2011-07-21

480

Processing of sintered alpha SiC  

NASA Technical Reports Server (NTRS)

Processing methods of sintered alpha SiC for engine applications are developed in a cost effective manner, using a submicron sized powder blended with sintering aids (boron and carbon). The processes for forming a green powder compact, such as dry pressing, cold isostatic pressing and green machining, slip casting, aqueous extrusion, plastic extrusion, and injection molding, are described. Dry pressing is the simplest route to component fabrication, and is carried out at approximately 10,000 psi pressure, while in the cold isostatic method the pressure could go as high as 20,000 psi. Surfactants are added to control settling rates and casting characteristics in the slip casting. The aqueous extrusion process is accomplished by a hydraulic ram forcing the aqueous mixture through a die. The plastic forming processes of extrusion and injection molding offer the potential of greater diversity in shape capacity. The physical properties of sintered alpha SiC (hardness, Young's modulus, shear modulus, and thermal diffusivity) are extensively tested. Corrosion resistance test results of silicon carbide are included.

Storm, R. S.

1984-01-01

481

Nonlinear feedback control for high alpha flight  

NASA Technical Reports Server (NTRS)

Analytical aerodynamic models are derived from a high alpha 6 DOF wind tunnel model. One detail model requires some interpolation between nonlinear functions of alpha. One analytical model requires no interpolation and as such is a completely continuous model. Flight path optimization is conducted on the basic maneuvers: half-loop, 90 degree pitch-up, and level turn. The optimal control analysis uses the derived analytical model in the equations of motion and is based on both moment and force equations. The maximum principle solution for the half-loop is poststall trajectory performing the half-loop in 13.6 seconds. The agility induced by thrust vectoring capability provided a minimum effect on reducing the maneuver time. By means of thrust vectoring control the 90 degrees pitch-up maneuver can be executed in a small place over a short time interval. The agility capability of thrust vectoring is quite beneficial for pitch-up maneuvers. The level turn results are based currently on only outer layer solutions of singular perturbation. Poststall solutions provide high turn rates but generate higher losses of energy than that of classical sustained solutions.

Stalford, Harold

1990-01-01

482

L-alpha intensity in coronal streamers  

NASA Technical Reports Server (NTRS)

White-light images are presently the primary source of information on physical conditions in the solar corona at distances greater than a few tenths of a solar radius above the limb. As a consequence, we still only have an incomplete description of structures extending beyond the solar limb. In particular, streamers, although observed for decades, represent a poorly known phenomenon. SOHO, to be launched in 1995, will be able to make long-term observations of these features up to heights of a few solar radii, both in white light and UV. In this paper we present simulations of L-alpha intensity in coronal streamers, based on the two-dimensional (2D) model developed by Wang et at. (1992, 1993) via a time-dependent numerical relaxation approach. Because the model is 2D, we make an a priori hypothesis about the extension of streamers in the third dimension. L-alpha data, obtained from a rocket (Kohl et al., 1983), allowed us to identify a shape which fits the observations.

Noci, G.; Poletto, G.; Suess, S. T.; Wang, A.-H.; Wu, S. T.

1993-01-01

483

MFTF-. cap alpha. + T progress report  

SciTech Connect

Early in FY 1983, several upgrades of the Mirror Fusion Test Facility (MFTF-B) at Lawrence Livermore National Laboratory (LLNL) were proposed to the fusion community. The one most favorably received was designated MFTF-..cap alpha..+T. The engineering design of this device, guided by LLNL, has been a principal activity of the Fusion Engineering Design Center during FY 1983. This interim progress report represents a snapshot of the device design, which was begun in FY 1983 and will continue for several years. The report is organized as a complete design description. Because it is an interim report, some parts are incomplete; they will be supplied as the design study proceeds. As described in this report, MFTF-..cap alpha..+T uses existing facilities, many MFTF-B components, and a number of innovations to improve on the physics parameters of MFTF-B. It burns deuterium-tritium and has a central-cell Q of 2, a wall loading GAMMA/sub n/ of 2 MW/m/sup 2/ (with a central-cell insert module), and an availability of 10%. The machine is fully shielded, allows hands-on maintenance of components outside the vacuum vessel 24 h after shutdown, and has provisions for repair of all operating components.

Nelson, W.D. (ed.)

1985-04-01

484

{alpha} decay of {sup 194}At  

SciTech Connect

Detailed {alpha}-decay studies of the neutron-deficient isotope {sup 194}At have been performed in the complete fusion reaction {sup 56}Fe+{sup 141}Pr{yields}{sup 194}At+3n at the velocity filter SHIP. Two {alpha}-decaying isomeric states with half-lives of T{sub 1/2}({sup 194}At{sup m1})=310(8) ms and T{sub 1/2}({sup 194}At{sup m2})=253(10) ms were identified in this nucleus. Their complex decays to the states in the daughter nucleus {sup 190}Bi are discussed in the article. We propose that similar to the case of the neighboring {sup 191,192,193,195}At isotopes, the oblate-deformed configurations based on the proton 1/2{sup +}[440] and/or 7/2{sup -}[514] Nilsson orbitals become important in {sup 194}At. A new isomeric state with the half-life of 175(8) ns was observed in {sup 190}Bi.

Andreyev, A. N. [Instituut voor Kern- en Stralingsfysica, K.U. Leuven, University of Leuven, B-3001 Leuven (Belgium); Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, V5A-1S6 (Canada); TRIUMF, 4004 Wesbrook Mall, Vancouver, British Columbia, V6T 2A3 (Canada); Antalic, S.; Streicher, B.; Saro, S.; Venhart, M. [Department of Nuclear Physics and Biophysics, Comenius University, Bratislava, SK-84248 (Slovakia); Ackermann, D.; Heinz, S.; Hessberger, F. P.; Kojouharov, I.; Kindler, B.; Lommel, B.; Mann, R.; Sulignano, B. [Gesellschaft fuer Schwerionenforschung, Planckstrasse 1, D-64291 Darmstadt (Germany); Bianco, L.; Page, R. D.; Sapple, P.; Thomson, J. [Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE (United Kingdom); Franchoo, S. [IPN Orsay, F-91406 Orsay Cedex (France); Hofmann, S. [Gesellschaft fuer Schwerionenforschung, Planckstrasse 1, D-64291 Darmstadt (Germany); Physikalisches Institut, J.W. Goethe-Universitaet, D-60054 Frankfurt (Germany); Huyse, M. [Instituut voor Kern- en Stralingsfysica, K.U. Leuven, University of Leuven, B-3001 Leuven (Belgium)] (and others)

2009-06-15

485

Alpha globulin injections and decreased gamma globulin production in chickens.  

PubMed

Electrophoretic analysis shows a strong similarity in the blood serums of chickens subjected to egg parabiosis and of chickens repeatedly injected with fraction IV (alpha globulins). In both instances there is an evident rise in the albumin-plus alpha(1) titer and an evident decrease in the gamma globulin levels. These findings suggest that the injection of alpha globulins has the same serum effect on the animal as parabiotically induced blood chimerism, namely, a reduction in circulating gamma globulin (immunoglobulins?). PMID:4162096

Kamrin, B B

1966-09-01

486

Waves for Alpha-Channeling in Mirror Machines  

SciTech Connect

Alpha-channeling can, in principle, be implemented in mirror machines via exciting weaklydamped modes in the ion cyclotron frequency range with perpendicular wavelengths smaller than the alpha particle gyroradius. Assuming quasi-longitudinal or quasi-transverse wave propagation, we search systematically for suitable modes in mirror plasmas. Considering two device designs, a proof-of-principle facility and a fusion rector prototype, we in fact identify candidate modes suitable for alpha-channeling.

A. I. Zhmoginov and N. J. Fisch

2009-07-08

487

Comparison of MRI Alpha Angle Measurement Planes in Femoroacetabular Impingement  

Microsoft Academic Search

Insufficient femoral head-neck offset is common in femoroacetabular impingement (FAI) and reflected by the alpha angle, a\\u000a validated measurement for quantifying this anatomic deformity in patients with FAI. We compared the alpha angle determined\\u000a on magnetic resonance imaging (MRI) oblique axial plane images with the maximal alpha angle value obtained using radial images.\\u000a The MRIs of 41 subjects with clinically

Kawan S. Rakhra; Adnan M. Sheikh; David Allen; Paul E. Beaulé

2009-01-01

488

AlphaSort: A Cache-Sensitive Parallel External Sort  

Microsoft Academic Search

A new sort algorithm, called AlphaSort, demonstrates that commodity processors and disks can handle commercial batch workloads. Using commod- ity processors, memory, and arrays of SCSI disks, AlphaSort runs the industry- standard sort benchmark in seven seconds. This beats the best published record on a 32-CPU 32-disk Hypercube by 8:1. On another benchmark, AlphaSort sorted more than a gigabyte in

Chris Nyberg; Tom Barclay; Zarka Cvetanovic; Jim Gray; David B. Lomet

1995-01-01

489

Evidence for Alpha Receptors in the Human Ureter  

NASA Astrophysics Data System (ADS)

An immunohistochemical and western blot expression analysis of human ureters was performed in order to characterize the alpha-1-adrenergic receptor distribution along the length of the human ureteral wall. Mapping the distribution will assist in understanding the potential role alpha -1-adrenergic receptors and their subtype density might have in the pathophysiology of ureteral colic and stone passage. Patients diagnosed with renal cancer or bladder cancer undergoing nephrectomy, nephroureterectomy, or cystectomy had ureteral specimens taken from the proximal, mid, distal and tunneled ureter. Tissues were processed for fresh frozen examination and fixed in formalin. None of the ureteral specimens were involved with cancer. Serial histologic sections and immunohistochemical studies were performed using antibodies specific for alpha-1-adrenergic receptor subtypes (alpha 1a, alpha 1b, alpha 1d). The sections were examined under a light microscope and scored as positive or negative. In order to validate and quantify the alpha receptor subtypes along the human ureter. Western blotting techniques were applied. Human ureter stained positively for alpha -1-adrenergic receptors. Immunostaining appeared red, with intense reaction in the smooth muscle of the ureter and endothelium of the neighboring blood vessels. There was differential expression between all the receptors with the highest staining for alpha-1D subtype. The highest protein expression for all three subtypes was in the renal pelvis and decreased with advancement along the ureter to the distal ureter. At the distal ureter, there was marked increase in expression as one progressed towards the ureteral orifice. The same pattern of protein expression was exhibited for all three alpha -1-adrenergic receptor subtypes. We provide preliminary evidence for the ability to detect and quantify the alpha-1-receptor subtypes along the human ureter which to the best of our knowledge has never been done with immunohistochemistry and molecular techniques. These findings may lend support to the preliminary studies of the effectiveness of alpha-receptor blockade on ureteral colic and stone passage.

Madeb, Ralph; Knopf, Joy; Golijanin, Dragan; Bourne, Patricia; Erturk, Erdal

2007-04-01

490

LE CHOIX DES ANTISEPTIQUES POUR LES PDILUVES DESTINS AUX BOVINS  

E-print Network

applications. On the other hand, weak organic matter resistance which seems to characterize Javel water des utilisateurs, on a donc réalisé, dans des conditions réelles d'uti- lisation, la comparaison de

Paris-Sud XI, Université de

491

Éléments d'écologie de la transmission d'Echinococcus multilocularis en Chine (Sichuan) Modélisation des distributions spatiales des communautés et populations des hôtes : des données de terrain aux prédictions.  

E-print Network

??La transmission du parasite Echinococcus multilocularis à l'origine d'une zoonose fatale chez l'homme, l'échinococcose alvéolaire, peut être modulée par des perturbations anthropiques de l'écologie des… (more)

Vaniscotte, Amélie

2009-01-01

492

Le contrôle des infections au cabinet du pédiatre  

PubMed Central

RÉSUMÉ La transmission des infections au cabinet du pédiatre est de plus en plus préoccupante. Le présent document expose les voies de transmission des infections et les principes sous-jacents aux mesures actuelles pour contrôler les infections. Pour prévenir les infections, il faut bien concevoir le cabinet et adopter des politiques administratives et de triage convenables, de même que des pratiques de base pour les soins de tous les patients (p. ex., hygiène des mains, port de gants, de masques, de lunettes de protection et d’une blouse d’hôpital pour des interventions précises; nettoyage, désinfection et stérilisation convenables des surfaces et du matériel, y compris les jouets, et techniques d’asepsie en cas d’interventions effractives) et des précautions additionnelles en cas d’infections précises. Le personnel doit avoir reçu les vaccins pertinents, et les personnes infectées doivent respecter les politiques de restriction au travail.

2008-01-01

493

La perte d'eau au cours de la rfrigration dans l'air des fruits et des lgumes La perte d'eau au cours  

E-print Network

de conservation comme les asperges et les cerises. Cette technique permet de refroidir rapidement aubergines, des poivrons, des courgettes, des concombres (340 000 tonnes), des artichauts, des asperges et (% poids) Légumes Asperge 94 Haricot vert 89 Melon 89 Tomate 94 Fruits Banane 75 Cerise 82 Orange 84 P

Paris-Sud XI, Université de

494

Alpha particle loss in the TFTR DT experiments  

SciTech Connect

Alpha particle loss was measured during the TFTR DT experiments using a scintillator detector located at the vessel bottom in the ion grad-B drift direction. The DT alpha particle loss to this detector was consistent with the calculated first-orbit loss over the whole range of plasma current I=0.6-2.7 MA. In particular, the alpha particle loss rate per DT neutron did not increase significantly with fusion power up to 10.7 MW, indicating the absence of any new ``collective`` alpha particle loss processes in these experiments.

Zweben, S.J.; Darrow, D.S.; Herrmann, H.W. [and others

1995-01-01

495

{alpha} decay half-lives of new superheavy elements  

SciTech Connect

The lifetimes of {alpha} decays of the recently produced isotopes of elements 112, 114, 116, and {sup 294}118 and of some decay products are calculated theoretically within the WKB approximation by use of microscopic {alpha}-nucleus interaction potentials. We obtain these nuclear potentials by folding the densities of the {alpha} and the daughter nuclei with the M3Y effective interaction, supplemented by a zero-range pseudopotential for exchange along with the density dependence. Spherical charge distributions are used for calculating the Coulomb interaction potentials. These calculations provide reasonable estimates for the observed {alpha} decay lifetimes and thus provide reliable predictions for other superheavies.

Chowdhury, P. Roy [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700 064 (India); Samanta, C. [Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Kolkata 700 064 (India); Physics Department, Virginia Commonwealth University, Richmond, Virginia 23284-2000 (United States); Basu, D.N. [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700 064 (India)

2006-01-15

496

ISS Update: Alpha Magnetic Spectrometer - Duration: 11:00.  

NASA Video Gallery

NASA Public Affairs Officer Kelly Humphries interviews Trent Martin, Johnson Space Center project manager for the Alpha Magnetic Spectrometer (AMS) aboard the International Space Station. Questions...

497

Alpha asymmetry in infants at risk for autism spectrum disorders.  

PubMed

An emerging focus of research on autism spectrum disorder (ASD) targets the identification of early-developing ASD endophenotypes using infant siblings of affected children. One potential neural endophenotype is resting frontal electroencephalogram (EEG) alpha asymmetry, a metric of hemispheric organization. Here, we examined the development of frontal EEG alpha asymmetry in ASD high-risk and low-risk infant populations. Our findings demonstrate that low and high-risk infants show different patterns of alpha asymmetry at 6 months of age and opposite growth trajectories in asymmetry over the following 12 months. These results support the candidacy of alpha asymmetry as an early neural ASD endophenotype. PMID:23989937

Gabard-Durnam, Laurel; Tierney, Adrienne L; Vogel-Farley, Vanessa; Tager-Flusberg, Helen; Nelson, Charles A

2015-02-01

498

Studies of alpha-granule proteins in cultured human megakaryocytes.  

PubMed

alpha-Granule protein storage is important for producing platelets with normal haemostatic function. The low to undetectable levels of several megakaryocyte-synthesized alpha-granule proteins in normal plasma suggest megakaryocytes are important to sequester these proteins in vivo. alpha-Granule protein storage in vitro has been studied using other cell types, with differences observed in how some proteins are processed compared to platelets. Human megakaryocytes, cultured from cord blood CD34(+) cells and grown in serum-free media containing thrombopoietin, were investigated to determine if they could be used as a model for studying normal alpha-granule protein processing and storage. ELISA indicated that cultured megakaryocytes contained the alpha-granule proteins multimerin, von Willebrand factor, thrombospondin-1, beta-thromboglobulin and platelet factor 4, but no detectable fibrinogen and factor V. A significant proportion of the alpha-granule protein in megakaryocyte cultures was contained within the cells (averages: 41-71 %), consistent with storage. Detailed analyses of multimerin and von Willebrand factor confirmed that alpha-granule proteins were processed to mature forms and were predominantly located in the alpha-granules of cultured megakaryocytes.Thrombopoietin-stimulated cultured megakaryocytes provide a useful model for studying alpha-granule protein processing and storage. PMID:14597980

Veljkovic, Dragoslava Kika; Cramer, Elisabeth M; Alimardani, Gulie; Fichelson, Serge; Massé, Jean-Marc; Hayward, Catherine P M

2003-11-01

499

Staphylococcal alpha-toxin causes increased tracheal epithelial permeability.  

PubMed

Staphylococcus aureus is an important cause of pulmonary infections. The role of S. aureus alpha-toxin as a virulence factor is unclear. We hypothesized that airway epithelium is a target of S. aureus alpha-toxin and that exposure of airway epithelium to alpha-toxin results in damage to the airway epithelium. To examine the hypothesis that alpha-toxin is capable of independently producing airway epithelium damage as measured by permeability and morphometry, an isolated whole mouse trachea test apparatus was developed. In vitro epithelial permeability (P) was calculated and digital micrographs were analyzed morphometrically. Purified S. aureus alpha-toxin produced a significant increase in tracheal epithelial P (P < 0.05). Morphometric analysis revealed the ratio of adherent tracheal epithelium attached to the basement membrane divided by the total length of the basement membrane decreased in a dose-dependent manner with 1 microg/ml alpha-toxin and 10 microg/ml alpha-toxin (P < 0.05). We developed a novel isolated whole mouse trachea test apparatus for the measurement of tracheal epithelium damage. Increased P and separation of the tracheal epithelium from the basement membrane occurred after S. aureus alpha-toxin exposure. We conclude that mammalian airway epithelium is a target of S. aureus alpha-toxin. PMID:16998922

Phillips, James R; Tripp, Timothy J; Regelmann, Warren E; Schlievert, Patrick M; Wangensteen, O Douglas

2006-12-01

500

Identification of tryptophan oxidation products in bovine alpha-crystallin.  

PubMed Central

Oxidation is known to affect the structure, activity, and rate of degradation of proteins, and is believed to contribute to a variety of pathological conditions. Metal-catalyzed oxidation (MCO) is a primary oxidizing system in many cell types. In this study, the oxidative effects of a MCO system (the Fenton reaction) on the structure of the tryptophan residues of alpha-crystallin were determined. Tandem mass spectrometry (MS/MS) was utilized to identify specific tryptophan and methionine oxidation products in the bovine alpha-crystallin sequence. After oxidative exposure, alpha-crystallin was digested with trypsin, and the resulting peptides were fractionated by reverse-phase HPLC. Structural analysis by mass spectrometry revealed that tryptophan 9 of alphaA- and tryptophan 60 of alphaB-crystallin were each converted into hydroxytryptophans (HTRP), N-formylkynurenine (NFK), and kynurenine (KYN). However, only HTRP and KYN formation were detected at residue 9 of alphaB-crystallin. Oxidation of methionine 1 of alphaA- and methionine 1 and 68 of alphaB-crystallin was also detected. The products NFK and KYN are of particular importance in the lens, as they themselves are photosensitizers that can generate reactive oxygen species (ROS) upon UV light absorption. The unambiguous identification of HTRP, NFK, and KYN in intact alpha-crystallin represents the first structural proof of the formation of these products in an intact protein, and provides a basis for detailed structural analysis of oxidized proteins generated in numerous pathological conditions. PMID:9828005

Finley, E. L.; Dillon, J.; Crouch, R. K.; Schey, K. L.

1998-01-01