Science.gov

Sample records for desy scientific annual

  1. Scientific Directory 1977 and Annual Bibliography 1976.

    ERIC Educational Resources Information Center

    National Institutes of Health, (DHEW), Bethesda, MD. Div. of Scientific Reports.

    The Scientific Directory and Annual Bibliography of the National Institutes of Health (NIH) is intended for reference use by research workers in the biomedical sciences. It presents a broad outline of NIH organizational structure, the professional staff, and their scientific and technical publications covering work done at NIH. The volume also…

  2. Graphics at DESY

    NASA Astrophysics Data System (ADS)

    Schilling, Peter K.

    1989-12-01

    After a short history of computer graphics at DESY the introduction of graphic workstations based on true and "quasi" standards is described. An overview of graphics hardware and software at DESY is given as well as the communication facilities used. Some remarks about current and future development finish the paper.

  3. The DESY Grid Centre

    NASA Astrophysics Data System (ADS)

    Haupt, A.; Gellrich, A.; Kemp, Y.; Leffhalm, K.; Ozerov, D.; Wegner, P.

    2012-12-01

    DESY is one of the world-wide leading centers for research with particle accelerators, synchrotron light and astroparticles. DESY participates in LHC as a Tier-2 center, supports on-going analyzes of HERA data, is a leading partner for ILC, and runs the National Analysis Facility (NAF) for LHC and ILC in the framework of the Helmholtz Alliance, Physics at the Terascale. For the research with synchrotron light major new facilities are operated and built (FLASH, PETRA-III, and XFEL). DESY furthermore acts as Data-Tier1 centre for the Neutrino detector IceCube. Established within the EGI-project DESY operates a grid infrastructure which supports a number of virtual Organizations (VO), incl. ATLAS, CMS, and LHCb. Furthermore, DESY hosts some of HEP and non-HEP VOs, such as the HERA experiments and ILC as well as photon science communities. The support of the new astroparticle physics VOs IceCube and CTA is currently set up. As the global structure of the grid offers huge resources which are perfect for batch-like computing, DESY has set up the National Analysis Facility (NAF) which complements the grid to allow German HEP users for efficient data analysis. The grid infrastructure and the NAF use the same physics data which is distributed via the grid. We call the conjunction of grid and NAF the DESY Grid Centre. In the contribution to CHEP2012 we will in depth discuss the conceptional and operational aspects of our multi-VO and multi-community Grid Centre and present the system setup. We will in particular focus on the interplay of Grid and NAF and present experiences of the operations.

  4. Centrally managed tapes at DESY

    SciTech Connect

    Hell, O.

    1994-12-31

    Tapes at DESY are managed by the computer center and thus offer virtually unlimited storage space to the DESY computer center users. This paper describes the most recent version of the DESY tape management system, its predecessors having been in service for many years.

  5. The FLASHForward facility at DESY

    NASA Astrophysics Data System (ADS)

    Aschikhin, A.; Behrens, C.; Bohlen, S.; Dale, J.; Delbos, N.; di Lucchio, L.; Elsen, E.; Erbe, J.-H.; Felber, M.; Foster, B.; Goldberg, L.; Grebenyuk, J.; Gruse, J.-N.; Hidding, B.; Hu, Zhanghu; Karstensen, S.; Knetsch, A.; Kononenko, O.; Libov, V.; Ludwig, K.; Maier, A. R.; Martinez de la Ossa, A.; Mehrling, T.; Palmer, C. A. J.; Pannek, F.; Schaper, L.; Schlarb, H.; Schmidt, B.; Schreiber, S.; Schwinkendorf, J.-P.; Steel, H.; Streeter, M.; Tauscher, G.; Wacker, V.; Weichert, S.; Wunderlich, S.; Zemella, J.; Osterhoff, J.

    2016-01-01

    The FLASHForward project at DESY is a pioneering plasma-wakefield acceleration experiment that aims to produce, in a few centimetres of ionised hydrogen, beams with energy of order GeV that are of quality sufficient to be used in a free-electron laser. The plasma is created by ionising a gas in a gas cell with a multi-TW laser system. The plasma wave will be driven by high-current-density electron beams from the FLASH linear accelerator. The laser system can also be used to provide optical diagnostics of the plasma and electron beams due to the <30 fs synchronisation between the laser and the driving electron beam. The project will explore both external and internal witness-beam injection techniques. The operation parameters of the experiment are discussed, as well as the scientific programme.

  6. ATR National Scientific User Facility 2013 Annual Report

    SciTech Connect

    Ulrich, Julie A.; Robertson, Sarah

    2015-03-01

    This is the 2013 Annual Report for the Advanced Test Reactor National Scientific User Facility. This report includes information on university-run research projects along with a description of the program and the capabilities offered researchers.

  7. Progress in Scientific and Technical Communications, 1968 Annual Report.

    ERIC Educational Resources Information Center

    Federal Council for Science and Technology, Washington, DC. Committee on Scientific and Technical Information.

    This sixth annual report describes progress achieved by the Federal Government in improving the communication of scientific and technical information to support and enhance national science and technology. Included in the report are details regarding the scientific and technical activities of individual Federal Agencies, such as the Atomic Energy…

  8. TCGA Third Annual Scientific Symposium - TCGA

    Cancer.gov

    Monday, May 12 - Tuesday, May 13, 2014 National Institutes of Health, Bethesda, Md. This open scientific meeting will consist of collaborative workshops, poster sessions, and plenary sessions. Registration is now open.

  9. Detector developments at DESY.

    PubMed

    Wunderer, Cornelia B; Allahgholi, Aschkan; Bayer, Matthias; Bianco, Laura; Correa, Jonathan; Delfs, Annette; Göttlicher, Peter; Hirsemann, Helmut; Jack, Stefanie; Klyuev, Alexander; Lange, Sabine; Marras, Alessandro; Niemann, Magdalena; Pithan, Florian; Reza, Salim; Sheviakov, Igor; Smoljanin, Sergej; Tennert, Maximilian; Trunk, Ulrich; Xia, Qingqing; Zhang, Jiaguo; Zimmer, Manfred; Das, Dipayan; Guerrini, Nicola; Marsh, Ben; Sedgwick, Iain; Turchetta, Renato; Cautero, Giuseppe; Giuressi, Dario; Menk, Ralf; Khromova, Anastasiya; Pinaroli, Giovanni; Stebel, Luigi; Marchal, Julien; Pedersen, Ulrik; Rees, Nick; Steadman, Paul; Sussmuth, Mark; Tartoni, Nicola; Yousef, Hazem; Hyun, HyoJung; Kim, KyungSook; Rah, Seungyu; Dinapoli, Roberto; Greiffenberg, Dominic; Mezza, Davide; Mozzanica, Aldo; Schmitt, Bernd; Shi, Xintian; Krueger, Hans; Klanner, Robert; Schwandt, Joem; Graafsma, Heinz

    2016-01-01

    With the increased brilliance of state-of-the-art synchrotron radiation sources and the advent of free-electron lasers (FELs) enabling revolutionary science with EUV to X-ray photons comes an urgent need for suitable photon imaging detectors. Requirements include high frame rates, very large dynamic range, single-photon sensitivity with low probability of false positives and (multi)-megapixels. At DESY, one ongoing development project - in collaboration with RAL/STFC, Elettra Sincrotrone Trieste, Diamond, and Pohang Accelerator Laboratory - is the CMOS-based soft X-ray imager PERCIVAL. PERCIVAL is a monolithic active-pixel sensor back-thinned to access its primary energy range of 250 eV to 1 keV with target efficiencies above 90%. According to preliminary specifications, the roughly 10 cm × 10 cm, 3.5k × 3.7k monolithic sensor will operate at frame rates up to 120 Hz (commensurate with most FELs) and use multiple gains within 27 µm pixels to measure 1 to ∼100000 (500 eV) simultaneously arriving photons. DESY is also leading the development of the AGIPD, a high-speed detector based on hybrid pixel technology intended for use at the European XFEL. This system is being developed in collaboration with PSI, University of Hamburg, and University of Bonn. The AGIPD allows single-pulse imaging at 4.5 MHz frame rate into a 352-frame buffer, with a dynamic range allowing single-photon detection and detection of more than 10000 photons at 12.4 keV in the same image. Modules of 65k pixels each are configured to make up (multi)megapixel cameras. This review describes the AGIPD and the PERCIVAL concepts and systems, including some recent results and a summary of their current status. It also gives a short overview over other FEL-relevant developments where the Photon Science Detector Group at DESY is involved. PMID:26698052

  10. Accelerating scientific discovery : 2007 annual report.

    SciTech Connect

    Beckman, P.; Dave, P.; Drugan, C.

    2008-11-14

    As a gateway for scientific discovery, the Argonne Leadership Computing Facility (ALCF) works hand in hand with the world's best computational scientists to advance research in a diverse span of scientific domains, ranging from chemistry, applied mathematics, and materials science to engineering physics and life sciences. Sponsored by the U.S. Department of Energy's (DOE) Office of Science, researchers are using the IBM Blue Gene/L supercomputer at the ALCF to study and explore key scientific problems that underlie important challenges facing our society. For instance, a research team at the University of California-San Diego/ SDSC is studying the molecular basis of Parkinson's disease. The researchers plan to use the knowledge they gain to discover new drugs to treat the disease and to identify risk factors for other diseases that are equally prevalent. Likewise, scientists from Pratt & Whitney are using the Blue Gene to understand the complex processes within aircraft engines. Expanding our understanding of jet engine combustors is the secret to improved fuel efficiency and reduced emissions. Lessons learned from the scientific simulations of jet engine combustors have already led Pratt & Whitney to newer designs with unprecedented reductions in emissions, noise, and cost of ownership. ALCF staff members provide in-depth expertise and assistance to those using the Blue Gene/L and optimizing user applications. Both the Catalyst and Applications Performance Engineering and Data Analytics (APEDA) teams support the users projects. In addition to working with scientists running experiments on the Blue Gene/L, we have become a nexus for the broader global community. In partnership with the Mathematics and Computer Science Division at Argonne National Laboratory, we have created an environment where the world's most challenging computational science problems can be addressed. Our expertise in high-end scientific computing enables us to provide guidance for applications

  11. Advanced Test Reactor National Scientific User Facility 2010 Annual Report

    SciTech Connect

    Mary Catherine Thelen; Todd R. Allen

    2011-05-01

    This is the 2010 ATR National Scientific User Facility Annual Report. This report provides an overview of the program for 2010, along with individual project reports from each of the university principal investigators. The report also describes the capabilities offered to university researchers here at INL and at the ATR NSUF partner facilities.

  12. The 20th Annual Prostate Cancer Foundation Scientific Retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2014-06-01

    The 20th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 24 to 26, 2013, in National Harbor, Maryland. This event is held annually for the purpose of convening a diverse group of leading experimental and clinical researchers from academia, industry, and government to present and discuss critical and emerging topics relevant to prostate cancer (PCa) biology, and the diagnosis, prognosis, and treatment of PCa patients, with a focus on results that will lend to treatments for the most life-threatening stages of this disease. The themes that were highlighted at this year's event included: (i) mechanisms of PCa initiation and progression: cellular origins, neurons and neuroendocrine PCa, long non-coding RNAs, epigenetics, tumor cell metabolism, tumor-immune interactions, and novel molecular mechanisms; (ii) advancements in precision medicine strategies and predictive biomarkers of progression, survival, and drug sensitivities, including the analysis of circulating tumor cells and cell-free tumor DNA-new methods for liquid biopsies; (iii) new treatments including epigenomic therapy and immunotherapy, discovery of new treatment targets, and defining and targeting mechanisms of resistance to androgen-axis therapeutics; and (iv) new experimental and clinical epidemiology methods and techniques, including PCa population studies using patho-epidemiology. PMID:24719035

  13. The 22nd annual prostate cancer foundation scientific retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2016-09-01

    The 22nd Annual Prostate Cancer Foundation (PCF) Scientific Retreat was convened in Washington, D.C. from October 8 to 10, 2015. This event is the foremost scientific conference in the world focusing on basic, translational, and clinical prostate cancer research with the highest potential for accelerating the understanding of prostate cancer biology and improving the lives and outcomes of prostate cancer patients. Topics highlighted during the 2015 Retreat included: (i) new strategies and treatments for localized high-risk, hormone-naïve, oligometastatic, castrate-resistant, and treatment-refractory prostate cancer settings; (ii) the biology and genomics of tumor heterogeneity and tumor evolution; (iii) new understandings on the mechanisms and targeting of oncogenic drivers of prostate cancer; (iv) bioengineering of novel therapies and drug delivery methods; (v) innovative approaches to tumor immunotherapy; (vi) emerging molecular imaging technologies with improved sensitivity and specificity; and (vii) advancements in prognostic and predictive biomarkers and precision medicine strategies. Prostate 76:1037-1052, 2016. © 2016 Wiley Periodicals, Inc. PMID:27272144

  14. Novel Aspects of the DESI Data Acquisition System

    NASA Astrophysics Data System (ADS)

    Beaufore, Lucas; Honscheid, Klaus; Elliott, Ann; Dark Energy Spectroscopic Instrument Collaboration

    2015-04-01

    The Dark Energy Spectroscopic Instrument (DESI) will measure the effect of dark energy on the expansion of the universe. It will obtain optical spectra for tens of millions of galaxies and quasars, constructing a 3-dimensional map spanning the nearby universe to 10 billion light years. The survey will be conducted on the Mayall 4-meter telescope at Kitt Peak National Observatory starting in 2018. In order to achieve these scientific goals the DESI collaboration is building a high throughput spectrograph capable of observing thousands of spectra simultaneously. In this presentation we discuss the DESI instrument control and data acquisition system that is currently being developed to operate the 5,000 fiber positioners in the focal plane, the 10 spectrographs each with three CDD cameras and every other aspect of the instrument. Special emphasis will be given to novel aspects of the design including the use of inexpensive Linux-based microcontrollers such as the Raspberry PI to control a number of DESI hardware components.

  15. Highlights from the scientific and educational abstracts presented at the ASER 2015 annual scientific meeting and postgraduate course.

    PubMed

    Myers, Lee A; Herr, Keith D

    2016-06-01

    The American Society of Emergency Radiology (ASER) 2015 Annual Scientific Meeting and Postgraduate Course offered dedicated learning sessions, oral presentations, and digital exhibits on a broad spectrum of topics in emergency radiology, including traumatic and non-traumatic emergencies, quality, communication, education, technological innovations, and the evolving identity of the emergency radiology subspecialty. This article highlights the scientific and educational abstracts presented at the meeting. PMID:26884403

  16. Salt Tolerance of Desorption Electrospray Ionization (DESI)

    SciTech Connect

    Jackson, Ayanna U.; Talaty, Nari; Cooks, R G; Van Berkel, Gary J

    2007-01-01

    Suppression of ion intensity in the presence of high salt matrices is common in most mass spectrometry ionization techniques. Desorption electrospray ionization (DESI) is an ionization method that exhibits salt tolerance, and this is investigated. DESI analysis was performed on three different drug mixtures in the presence of 0, 0.2, 2, 5, 10, and 20% NaCl:KCl weight by volume from seven different surfaces. At physiological concentrations individual drugs in each mixture were observed with each surface. Collision-induced dissociation (CID) was used to provide additional confirmation for select compounds. Multiple stage experiments, to MS5, were performed for select compounds. Even in the absence of added salt, the benzodiazepine containing mixture yielded sodium and potassium adducts of carbamazepine which masked the ions of interest. These adducts were eliminated by adding 0.1% 7M ammonium acetate to the standard methanol:water (1:1) spray solvent. Comparison of the salt tolerance of DESI with that of electrospray ionization (ESI) demonstrated much better signal/noise characteristics for DESI in this study. The salt tolerance of DESI was also studied by performing limit of detection and dynamic range experiments. Even at a salt concentration significantly above physiological concentrations, select surfaces were effective in providing spectra that allowed the ready identification of the compounds of interest. The already high salt tolerance of DESI can be optimized further by appropriate choices of surface and spray solution.

  17. National Energy Research Scientific Computing Center 2007 Annual Report

    SciTech Connect

    Hules, John A.; Bashor, Jon; Wang, Ucilia; Yarris, Lynn; Preuss, Paul

    2008-10-23

    This report presents highlights of the research conducted on NERSC computers in a variety of scientific disciplines during the year 2007. It also reports on changes and upgrades to NERSC's systems and services aswell as activities of NERSC staff.

  18. The DESI Wide Field Corrector Optics

    SciTech Connect

    Doel, Peter; Sholl, Michael J.; Liang, Ming; Brooks, David; Flaugher, Brenna; Gutierrez, Gaston; Kent, Stephen; Lampton, Michael; Miller, Timothy; Sprayberry, David

    2014-01-01

    The Dark Energy Spectroscopic instrument (DESI) is a 5000 fiber multi-object spectrometer system under development for installation on the National Optical Astronomy Observatory (NOAO) Kitt Peak 4m telescope (the Mayall telescope). DESI is designed to perform a 14,000˚ (square) galaxy and Quasi-Stellar Object (QSO) redshift survey to improve estimates of the dark energy equation of state. The survey design imposes numerous constraints on a prime focus corrector design, including field of view, geometrical blur, stability, fiber injection efficiency, zenith angle, mass and cost. The DESI baseline wide-field optical design described herein provides a 3.2˚ diameter field of view with six 0.8- 1.14m diameter lenses and an integral atmospheric dispersion compensator.

  19. Institute for Scientific Computing Research Annual Report: Fiscal Year 2004

    SciTech Connect

    Keyes, D E

    2005-02-07

    Large-scale scientific computation and all of the disciplines that support and help to validate it have been placed at the focus of Lawrence Livermore National Laboratory (LLNL) by the Advanced Simulation and Computing (ASC) program of the National Nuclear Security Administration (NNSA) and the Scientific Discovery through Advanced Computing (SciDAC) initiative of the Office of Science of the Department of Energy (DOE). The maturation of computational simulation as a tool of scientific and engineering research is underscored in the November 2004 statement of the Secretary of Energy that, ''high performance computing is the backbone of the nation's science and technology enterprise''. LLNL operates several of the world's most powerful computers--including today's single most powerful--and has undertaken some of the largest and most compute-intensive simulations ever performed. Ultrascale simulation has been identified as one of the highest priorities in DOE's facilities planning for the next two decades. However, computers at architectural extremes are notoriously difficult to use efficiently. Furthermore, each successful terascale simulation only points out the need for much better ways of interacting with the resulting avalanche of data. Advances in scientific computing research have, therefore, never been more vital to LLNL's core missions than at present. Computational science is evolving so rapidly along every one of its research fronts that to remain on the leading edge, LLNL must engage researchers at many academic centers of excellence. In Fiscal Year 2004, the Institute for Scientific Computing Research (ISCR) served as one of LLNL's main bridges to the academic community with a program of collaborative subcontracts, visiting faculty, student internships, workshops, and an active seminar series. The ISCR identifies researchers from the academic community for computer science and computational science collaborations with LLNL and hosts them for short- and

  20. ACP research and scientific coordination: Annual performance report

    SciTech Connect

    Hales, J.M.

    1992-09-17

    This research grant addresses two primary objectives: 1. Conduct of specific research tasks under the DOE Atmospheric Chemistry Program (ACP), and 2. Provision of scientific coordination for the Atmospheric Chemistry Program. In summary, the project is progressing essentially as expected, with some minor exceptions. Higher than anticipated demands within Objective 2, associated primarily with the ACP Ozone Project and the recompetition of the National Laboratories protion of ACP, have resulted in a somewhat higher proportionate emphasis on the coordination activities associated with this objective. Also, the immediate need for pre-campaign modeling of the North Pacific has resulted in an acceleration of the Pacific modeling task relative to other tasks, particularly the Atlantic modeling task. Modeling activities in general have been delayed somewhat because of the noted Objective 2 demands and because of the extended time that was necessary to complete financial agreements for this grant.

  1. The New Hyperspectral Sensor Desis on the Multi-Payload Platform Muses Installed on the Iss

    NASA Astrophysics Data System (ADS)

    Müller, R.; Avbelj, J.; Carmona, E.; Eckardt, A.; Gerasch, B.; Graham, L.; Günther, B.; Heiden, U.; Ickes, J.; Kerr, G.; Knodt, U.; Krutz, D.; Krawczyk, H.; Makarau, A.; Miller, R.; Perkins, R.; Walter, I.

    2016-06-01

    The new hyperspectral instrument DLR Earth Sensing Imaging Spectrometer (DESIS) will be developed and integrated in the Multi-User-System for Earth Sensing (MUSES) platform installed on the International Space Station (ISS). The DESIS instrument will be launched to the ISS mid of 2017 and robotically installed in one of the four slots of the MUSES platform. After a four month commissioning phase the operational phase will last at least until 2020. The MUSES / DESIS system will be commanded and operated by the publically traded company TBE (Teledyne Brown Engineering), which initiated the whole program. TBE provides the MUSES platform and the German Aerospace Center (DLR) develops the instrument DESIS and establishes a Ground Segment for processing, archiving, delivering and calibration of the image data mainly used for scientific and humanitarian applications. Well calibrated and harmonized products will be generated together with the Ground Segment established at Teledyne. The article describes the Space Segment consisting of the MUSES platform and the instrument DESIS as well as the activities at the two (synchronized) Ground Segments consisting of the processing methods, product generation, data calibration and product validation. Finally comments to the data policy are given.

  2. Institute for Scientific Computing Research Fiscal Year 2002 Annual Report

    SciTech Connect

    Keyes, D E; McGraw, J R; Bodtker, L K

    2003-03-11

    The Institute for Scientific Computing Research (ISCR) at Lawrence Livermore National Laboratory is jointly administered by the Computing Applications and Research Department (CAR) and the University Relations Program (URP), and this joint relationship expresses its mission. An extensively externally networked ISCR cost-effectively expands the level and scope of national computational science expertise available to the Laboratory through CAR. The URP, with its infrastructure for managing six institutes and numerous educational programs at LLNL, assumes much of the logistical burden that is unavoidable in bridging the Laboratory's internal computational research environment with that of the academic community. As large-scale simulations on the parallel platforms of DOE's Advanced Simulation and Computing (ASCI) become increasingly important to the overall mission of LLNL, the role of the ISCR expands in importance, accordingly. Relying primarily on non-permanent staffing, the ISCR complements Laboratory research in areas of the computer and information sciences that are needed at the frontier of Laboratory missions. The ISCR strives to be the ''eyes and ears'' of the Laboratory in the computer and information sciences, in keeping the Laboratory aware of and connected to important external advances. It also attempts to be ''feet and hands, in carrying those advances into the Laboratory and incorporating them into practice. In addition to conducting research, the ISCR provides continuing education opportunities to Laboratory personnel, in the form of on-site workshops taught by experts on novel software or hardware technologies. The ISCR also seeks to influence the research community external to the Laboratory to pursue Laboratory-related interests and to train the workforce that will be required by the Laboratory. Part of the performance of this function is interpreting to the external community appropriate (unclassified) aspects of the Laboratory's own contributions

  3. Large Grain Superconducting RF Cavities at DESY

    SciTech Connect

    Singer, W.; Brinkmann, A.; Ermakov, A.; Iversen, J.; Kreps, G.; Matheisen, A.; Proch, D.; Reschke, D.; Singer, X.; Spiwek, M.; Wen, H.; Brokmeier, H. G.

    2007-08-09

    The DESY R and D program on cavities fabricated from large grain niobium explores the potential of this material for the production of approx. 1000 nine-cell cavities for the European XFEL. The program investigates basic material properties, comparing large grain material to standard sheet niobium, as well as fabrication and preparation aspects. Several single-cell cavities of TESLA shape have been fabricated from large grain niobium. A gradient up to 41 MV/m at Q0 = 1.4{center_dot}1010 (TB = 2K) was measured after electropolishing. The first three large grain nine-cell cavities worldwide have been produced under contract of DESY with ACCEL Instruments Co. The first tests have shown that all three cavities reach an accelerating gradient up to 30 MV/m after BCP (Buffered Chemical Polishing) treatment, what exceeds the XFEL requirements for RF test in the vertical cryostat.

  4. 5 CFR 630.301 - Annual leave accrual and accumulation-Senior Executive Service, Senior-Level, and Scientific and...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Annual leave accrual and accumulation-Senior Executive Service, Senior-Level, and Scientific and Professional Employees. 630.301 Section 630.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS ABSENCE AND LEAVE Annual Leave § 630.301 Annual leave...

  5. Highlights of the 16th annual scientific sessions of the Society for Cardiovascular Magnetic Resonance

    PubMed Central

    2013-01-01

    The 16th Annual Scientific Sessions of the Society for Cardiovascular Magnetic Resonance (SCMR) took place in San Francisco, USA at the end of January 2013. With a faculty of experts from across the world, this congress provided a wealth of insight into cutting-edge research and technological development. This review article intends to provide a highlight of what represented the most significant advances in the field of cardiovascular magnetic resonance (CMR) during this year’s meeting. PMID:23870663

  6. British Society for Haematology, Slide session, Annual Scientific Meeting, Bournemouth, 2007.

    PubMed

    Bhavnani, M; Braithwaite, J; Burthem, J; Crotty, G; Gibson, B; Hutchinson, C; Jackson, G H; Layton, M; Lucas, G; Macartney, C; Matthey, F; Pardoe, L; Radia, D; Webb, S

    2008-04-01

    Eight cases discussed by experts at the 2007 Annual Scientific Meeting of the British Society of Haematology are presented as at the meeting, with a discussion of the morphological features, digital information and differential diagnosis being followed by further information and a final diagnosis. Additionally, digital slides of two of the cases were available to be viewed by the internet with the opportunity for delegates to suggest diagnoses. PMID:18284418

  7. The NAF: National analysis facility at DESY

    NASA Astrophysics Data System (ADS)

    Haupt, Andreas; Kemp, Yves

    2010-04-01

    Within the framework of a broad collaboration among German particle physicists, the strategic Helmholtz Alliance "Physics a the Terascale", an analysis facility has been set up at DESY. The facility is intended to provide the best possible analysis infrastructure for researches of the ATLAS, CMS, LHCb and ILC experiments and also for theory researchers. In a first part of the contribution, we will present the concept of the NAF and its place in the existing distributed grid landscape of the experiments. In a second part, the building blocks of the NAF will be detailed with an emphasis on technical implementations of some parts: - Usage of VOMS for separating grid resources between collaboration-wide and NAF-specific resources. - interactive and batch cluster and integration with PROOF. - usage of grid proxies to access work group servers and AFS. - the usage and operation of Lustre for fast data access. A special focus is the seamless integration of the facility into the two geographically separated DESY sites and its implications. In a third part, the experience of running the facility for one year will be reported.

  8. Hydroforming of Tesla Cavities at Desy

    SciTech Connect

    W. Singer; H. Kaiser; X. Singer; I. Gonin; I. Zhelezov; T. Khabibullin; P. Kneisel; K. Saito

    2000-07-01

    Since several years the development of seamless niobium cavity fabrication by hydro forming is being pursued at DESY. This technique offers the possibility of lower cost of fabrication and perhaps better rf performance of the cavities because of the elimination of electron-beam welds, which in the standard fabrication technique have sometimes lead to inferior cavity performance due to defects. Several single cell 1300 MHz cavities have been formed from high purity seamless niobium tubes, which are under computer control expanded with internal pressure while simultaneously being swaged axially. The seamless tubes have been made by either back extrusion and flow forming or by spinning or deep drawing. Standard surface treatment techniques such as high temperature post purification, buffered chemical polishing (BCP), electropolishing (EP) and high pressure ultra pure water rinsing (HPR) have been applied to these cavities. The cavities exhibited high Q - values of 2 x 10{sup 10} at 2K and residual resistances as low as 3 n{Omega} after the removal of a surface layer of app. 100 {micro}m by BCP. Surprisingly, even at high gradients up to the maximum measured values of E{sub acc} {approx} 33 MV/m the Q-value did not decrease in the absence of field emission as often observed. After electropolishing of additional 100 {micro}m one of the cavities reached an accelerating gradient of E{sub acc} {ge} 42 MV/m.

  9. Teaming Up for Women's Health: The 2015 American College of Obstetricians and Gynecologists Annual Clinical and Scientific Meeting.

    PubMed

    Breitkopf, Daniel M; Demosthenes, Lauren D; Phelan, Sharon T

    2015-11-01

    63rd Annual Clinical and Scientific Meeting of the American College of Obstetricians and Gynecologists, 2-6 May, 2015, San Francisco, CA, USA. In response to major practice changes in obstetrics and gynecology (OB/GYN), the 2015 Annual Clinical and Scientific Meeting of the American College of Obstetricians and Gynecologists responded with modification of the program organization, methods of presenting the information (debates, hands on, flip classrooms) and increased emphasis on current clinical research. The Presidential Program covered broad themes of changes in healthcare technology, teamwork in OB/GYN practice and the importance of advocating for patients. Over 400 abstracts representing a broad range of clinical and basic science research were presented. Changes in the Annual Clinical and Scientific Meeting should allow the membership to be more prepared and pro-active as the practice of OB/GYN evolves. PMID:26618933

  10. Prostate cancer: what did we learn from the 2012 Annual Scientific Meeting of ASCO?

    PubMed

    Burgess, Earle F; Raghavan, Derek

    2012-12-01

    In recent years, management of prostate cancer has benefited from an expanding array of new pharmacological options that are the result, in part, of an increased understanding of, and ability to target, androgen signaling. Further characterization of additional molecular pathways relevant to prostate cancer tumorigenesis has identified new molecular targets in prostate cancer that may be amenable to therapeutic intervention with novel agents. In addition, novel radioisotope therapies and cytotoxic agents have shown significant anticancer efficacy with manageable patterns of toxicity, and will eventually have to be integrated into our algorithms of therapy. This review summarizes recent findings in clinical prostate cancer research reported at the 2012 Annual Scientific Meeting of the American Society of Clinical Oncology (ASCO) and addresses their relevance to clinical practice. PMID:23413606

  11. Abstracts for the ninth annual scientific conference of the Prader-Willi syndrome (PWS) association

    SciTech Connect

    Fernhoff, P.M.

    1996-03-29

    The Ninth Annual Scientific Conference of the Prader-Willi Syndrome (PWS) Association (USA) met in Atlanta on July 20, 1994. The 17 papers which were presented ranged from those which explored the molecular origins of PWS to those that studied the most effective medical, behavioral, and nutritional management of affected children and adults. Several important messages emerged. The first was that although most patients with PWS have an interstitial deletion of 15q11q13 of paternal origin, and a smaller percentage of patients have maternal disomy, there can be several other morphologic alterations of chromosome 15 which cause PWS. As our understanding of these changes at the molecular level improves, we will better understand the nature of these unusual rearrangements. 1 fig., 2 tabs.

  12. Scientific overview: CSCI-CITAC annual general meeting and young investigator's forum 2011.

    PubMed

    Jamshidi, Farzad; Schmidt, Anna R; Belrose, Jillian C

    2013-01-01

    In 2011, members of the Clinician Investigator Trainee Association of Canada - Association des cliniciens-chercheurs en formation du Canada (CITAC-ACCFC) and the Canadian Society for Clinician Investigators (CSCI) held a joint Annual General Meeting (AGM) and Young Investigator Forum (YIF) September 12-14 in Ottawa, ON, Canada. The theme of the meeting was "The Role of Government and Regulatory Organizations in Shaping the Environment of the Clinician Scientist". The meeting was well attended by established clinician scientists and clinician investigator trainees from across Canada. The aim of this scientific overview is to highlight the research presented by trainees at both the oral plenary session as well as the poster presentation sessions of this meeting. This work covers a wide variety of medical disciplines, focusing on translational medicine, from the basic sciences to clinical application. PMID:23374600

  13. Tenth annual scientific conference of the Prader-Willi Syndrome Association (USA), July 19, 1995, Seattle, Washington

    SciTech Connect

    Holm, V.A.; Hudgins, L.; Cassidy, S.B. |

    1996-09-06

    Each year for the last 10 years, scientists conducting research on Prader-Willi syndrome have come together to exchange information during a scientific conference held in conjunction with the annual Prader-Willi Syndrome Association (USA) meeting. Presentations based on submitted abstracts encompass such varied fields as genetics, endocrinology, pediatrics, nutrition, psychology, psychiatry, and education. This year`s scientific conference was held in Seattle, Washington, on July 19, 1995, in conjunction with the 14th PWSA (USA) meeting held July 20-23. Seventeen reports were presented at the scientific meeting, the abstracts of which follow.

  14. 5 CFR 630.301 - Annual leave accrual and accumulation-Senior Executive Service, Senior-Level, and Scientific and...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... system established under 5 U.S.C. chapter 43 and 5 CFR part 430, subparts B and C, or other applicable... subject to 5 U.S.C. 5383; or (2) Holds a senior-level (SL) or scientific or professional (ST) position... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Annual leave accrual and...

  15. 5 CFR 630.301 - Annual leave accrual and accumulation-Senior Executive Service, Senior-Level, and Scientific and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... system established under 5 U.S.C. chapter 43 and 5 CFR part 430, subparts B and C, or other applicable... subject to 5 U.S.C. 5383; or (2) Holds a senior-level (SL) or scientific or professional (ST) position... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Annual leave accrual and...

  16. 5 CFR 630.301 - Annual leave accrual and accumulation-Senior Executive Service, Senior-Level, and Scientific and...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... system established under 5 U.S.C. chapter 43 and 5 CFR part 430, subparts B and C, or other applicable... subject to 5 U.S.C. 5383; or (2) Holds a senior-level (SL) or scientific or professional (ST) position... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Annual leave accrual and...

  17. 5 CFR 630.301 - Annual leave accrual and accumulation-Senior Executive Service, Senior-Level, and Scientific and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... system established under 5 U.S.C. chapter 43 and 5 CFR part 430, subparts B and C, or other applicable... subject to 5 U.S.C. 5383; or (2) Holds a senior-level (SL) or scientific or professional (ST) position... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Annual leave accrual and...

  18. The Dark Energy Spectroscopic Instrument (DESI): The NOAO DECam Legacy Imaging Survey and DESI Target Selection

    NASA Astrophysics Data System (ADS)

    Schlegel, David J.; Blum, Robert D.; Castander, Francisco Javier; Dey, Arjun; Finkbeiner, Douglas P.; Foucaud, Sebastien; Honscheid, Klaus; James, David; Lang, Dustin; Levi, Michael; Moustakas, John; Myers, Adam D.; Newman, Jeffrey; Nord, Brian; Nugent, Peter E.; Patej, Anna; Reil, Kevin; Rudnick, Gregory; Rykoff, Eli S.; Ford Schlafly, Eddie; Stark, Casey; Valdes, Francisco; Walker, Alistair R.; Weaver, Benjamin; DECam Legacy Survey Collaboration

    2015-01-01

    The DECam Legacy Survey will conduct a 3-band imaging survey of the Sloan Digital Sky Survey (SDSS) extragalactic footprint. The Dark Energy Camera (DECam) will be used to image the 6700 square degree footprint overlapping SDSS in the region -20 < Dec < +30 deg, to depths of g=24.7, r=23.9, z=23.0. The survey will be conducted from Fall 2014 through Spring 2017, with periodic data releases beginning in March 2015. These releases will include catalogs constructed with the Tractor-based multi-wavelength forced photometry applied to the DECam and WISE satellite data.The Dark Energy Spectroscopic Instrument (DESI) will observe 24 million galaxies and quasars in a 14,000 square degree extragalactic footprint. The targeting in that footprint will be provided by a combination of these DECam data, the MOSAIC camera on the Mayall 4-meter, and the 90Prime camera on the Bok Telescope.

  19. Scientific overview: CSCI-CITAC Annual General Meeting and Young Investigators' Forum 2014.

    PubMed

    Keow, Jonathan; Zhao, Eric; Samuel, Nardin; Dey, Ayan; Schneider, Raphael; Chen, Michael; Wang, Xin

    2015-01-01

    The Canadian Society of Clinician Investigators (CSCI) and Clinical Investigator Trainee Association of Canada/Association des cliniciens-chercheurs en formation du Canada (CITAC/ACCFC) annual general meeting (AGM) was held in Toronto during November 21-24, 2015 for the first time in conjunction with the University of Toronto Clinician-Investigator Program Research Day. The overall theme for this year's meeting was the role of mentorship in career development, with presentations from Dr. Chaim Bell (University of Toronto), Dr. Shurjeel Choudhri (Bayer Healthcare), Dr. Ken Croitoru (University of Toronto), Dr. Astrid Guttman (University of Toronto), Dr. Prabhat Jha (University of Toronto) and Dr. Sheila Singh (McMaster University). The keynote speakers of the 2014 AGM included Dr. Qutayba Hamid, who was presented with the Distinguished Scientist Award, Dr. Ravi Retnakaran, who was presented with the Joe Doupe Award, and Dr. Lorne Babiuk, who was the CSCI-RCPSC Henry Friesen Award winner. The highlight of the conference was, once again, the outstanding scientific presentations from the numerous clinician investigator (CI) trainees from across the country who presented at the Young Investigators' Forum. Their research topics spanned the diverse fields of science and medicine, ranging from basic science to cutting-edge translational research, and their work has been summarized in this review. Over 120 abstracts were presented at this year's meeting. This work was presented during two poster sessions, with the six most outstanding submitted abstracts presented in the form of oral presentations during the President's Forum. PMID:26278424

  20. The 1992 annual report on scientific programs: A broad research program on the sciences of complexity

    NASA Astrophysics Data System (ADS)

    In 1992 the Santa Fe Institute hosted more than 100 short- and long-term research visitors who conducted a total of 212 person-months of residential research in complex systems. To date this 1992 work has resulted in more than 50 SFI Working Papers and nearly 150 publications in the scientific literature. The Institute's book series in the sciences of complexity continues to grow, now numbering more than 20 volumes. The fifth annual complex systems summer school brought nearly 60 graduate students and postdoctoral fellows to Santa Fe for an intensive introduction to the field. Research on complex systems - the focus of work at SFI - involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex adaptive behavior range upwards from DNA through cells and evolutionary systems to human societies. Research models exhibiting complex behavior include spin glasses, cellular automata, and genetic algorithms. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simple components; (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, and the Gross National Product (GNP) of an economy); and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions.

  1. 1992 annual report on scientific programs: A broad research program on the sciences of complexity

    SciTech Connect

    Not Available

    1992-12-31

    In 1992 the Santa Fe Institute hosted more than 100 short- and long-term research visitors who conducted a total of 212 person-months of residential research in complex systems. To date this 1992 work has resulted in more than 50 SFI Working Papers and nearly 150 publications in the scientific literature. The Institute`s book series in the sciences of complexity continues to grow, now numbering more than 20 volumes. The fifth annual complex systems summer school brought nearly 60 graduate students and postdoctoral fellows to Santa Fe for an intensive introduction to the field. Research on complex systems-the focus of work at SFI-involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex adaptive behavior range upwards from DNA through cells and evolutionary systems to human societies. Research models exhibiting complex behavior include spin glasses, cellular automata, and genetic algorithms. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simple components; (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy); and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions.

  2. Overview of the 78th Annual Scientific Meeting of the Japanese Circulation Society.

    PubMed

    Watanabe, Masafumi

    2014-01-01

    The 78(th)Annual Scientific Meeting of the Japanese Circulation Society was held in Tokyo on March 21-23, 2014. The main theme was "Cardiology in the Information Era: From Bench to Community". Because of technological advancements, including computer networking, a vast amount of information from basic and clinical research is being generated in a short time period. This information has great potential to contribute to human health, and some of the results are presented. However, we must remain vigilant, for there are many risks inherent in information generation. To ensure high-quality information, we need to obtain enough knowledge to focus on not only the medicine, but also ethics, and methodology. Moreover, we need to train the specialists, establish economic support, and create a regulatory framework. More than 15,000 people, including paramedical specialists, attended this meeting. The most popular sessions included those on "Transcatheter Aortic Valve Implantation for Aortic Stenosis", "Diabetes Mellitus", "Atrial Fibrillation", "Pulmonary Hypertension", and "Diuretics To Treat Heart Failure". Even in rather small sessions, attendees participated in discussion, identified opportunities to expand or start research, and were able to update their clinical knowledge. The meeting was successfully completed with a discussion of the future of cardiology. PMID:25109361

  3. Scientific overview: CSCI-CITAC annual general meeting and young investigator's forum 2010.

    PubMed

    Berger, Mike; Bosse, Dominick; Kuruvilla, M Sara; Lang, Pencilla; Murray, Jean-Christophe; Nguyen, Long Viet

    2011-01-01

    In 2010, the annual general meeting of the Clinical Investigator Trainee Association of Canada - Association des cliniciens-chercheurs en formation du Canada (CITAC-ACCFC) and the Canadian Society for Clinician Investigators (CSCI) was held between September 20 and 22 in Ottawa. Several globally-renowned scientists, including this year's CSCI/Royal College Henry Friesen Award recipient, Dr. Paul Kubes, Distinguished Scientist Award recipient, Dr. Gideon Koren and Joe Doupe Young Investigator Award recipient, Dr. Torsten Neil, discussed a variety of topics relating to the role of technology in medicine. The meeting was well attended by clinician scientists and trainees from across Canada and offered trainees mentorship and networking opportunities in addition to showcasing their research at the young investigator forum. The aim of this scientific overview is to highlight the research presented by trainees at both the oral plenary session as well as the poster presentation sessions of this meeting. Similar to last year's meeting [1], research questions being investigated by trainees covered the spectrum of medical disciplines, encompassing both basic science as well as clinical areas, and are summarized below. PMID:21463544

  4. Scientific overview: CSCI - CITAC Annual General Meeting and Young Investigator's Forum 2012.

    PubMed

    Antoun, Ghadi; Ram, Véronique D; Wang, Xin; Wilcox, Jared T; Yoon, Ju-Yoon

    2013-01-01

    In 2012, the Annual General Meeting of the Clinical Investigator Trainee Association of Canada - Association des cliniciens-chercheurs en formation du Canada (CITAC - ACCFC) and the Canadian Society of Clinician Investigators (CSCI) was held 19-21 September in Ottawa. Several globally-renowned scientists, including 2012 Friesen International Prize recipient, Dr. Marc Tessier-Lavigne, the CSCI/Royal College Henry Friesen Award recipient, Dr. Morley Hollenberg, and the recipient of the Joe Doupe Young Investigator Award, Dr. Phillip Awadalla, presented on a range of topics on research in basic and translational science in medicine. This year's CITAC Symposium featured presentations by Dr. Alain Beaudet, Dr. Michael Strong and Dr. Vivek Goel on the Role of Physician Scientists in Public Health and Policy, which was followed by a lively discussion on the role of basic science and clinical research in patient-oriented policy development. This scientific overview highlights the research presented by trainees at both the oral plenary and poster presentation sessions. As at previous meetings, research questions investigated by this year's trainees span multiple medical disciplines; from basic science to clinical research to medical education. Below is a summary of the presentations showcased at the Young Investigator's Forum. PMID:24088329

  5. Coupling of Ultrafast LC with Mass Spectrometry by DESI

    NASA Astrophysics Data System (ADS)

    Cai, Yi; Liu, Yong; Helmy, Roy; Chen, Hao

    2014-10-01

    Recently we reported a desorption electrospray ionization (DESI) interface to combine liquid chromatography (LC) with mass spectrometry (MS) using a new LC eluent splitting strategy through a tiny orifice on LC capillary tube [ J. Am. Soc. Mass Spectrom. 25, 286 (2014)]. The interface introduces negligible dead volume and back pressure, thereby allowing "near real-time" MS detection, fast LC elution, and online MS-directed purification. This study further evaluates the LC/DESI-MS performance with focus of using ultra-fast LC. Using a monolithic C18 column, metabolites in urine can be separated within 1.6 min and can be online collected for subsequent structure elucidation (e.g., by NMR, UV, IR) in a recovery yield up to 99%. Using a spray solvent with alkaline pH, negative ions could be directly generated for acidic analytes (e.g., ibuprofen) in acidic LC eluent by DESI, offering a novel protocol to realize "wrong-way around" ionization for LC/MS analysis. In addition, DESI-MS is found to be compatible with ultra-performance liquid chromatography (UPLC) for the first time.

  6. Annual report to Congress, fiscal year 1997. A report by the Scientific Advisory Board of the Strategic Environmental Research and Development Program: Annual report number 6

    SciTech Connect

    1998-03-01

    Section 2904(h) of Title 10, United States Code, requires that an annual report of the Strategic Environmental Research and Development Program (SERDP) Scientific Advisory Board (SAB) be submitted to Congress no later than March 15 of each year. The Annual Report is required to describe the actions of the SAB during the preceding year and to provide any recommendations, including recommendations related to projects, programs, information exchange, and additional legislation within the scope of SERDP. This is the sixth Annual Report of the SERDP SAB and includes SAB activities and Program recommendations during FY97. Specifically, SERDP should focus on research that is: essential for the solution of major defense mission-readiness related problems; scientifically plausible; focused on areas where progress under other program sponsorship in DoD and/or other agencies is not sufficient or satisfactory; catalytic in nature to initiate, organize, and accelerate essential research in partnership with the Federal and private sector; and provides sufficient proof-of-principle demonstrations to attract follow-on Research Development Test and Engineering (RDT and E) support.

  7. National Society of Black Physicists XXV Annual Day of Scientific Lectures and 21st Annual Meeting - NSBP '98: The Next Generation/12th Annual National Conference of Black Physics Students - NCPBS '98: Physics/Life in Motion

    SciTech Connect

    MacKellar, Alan

    1999-02-28

    The 12th Annual National Conference of Black Physics Students (NCBPS) was held jointly with the Annual Meeting of the National Society of Black Physicists (NSBP) March 4-8, 1998 in Lexington, Ky. The Proceedings consists of scientific talks and abstracts given by NSBP members and students attending the NCBPS meeting. One joint session of general scientific interest was held, with NCBPS students, NSBP members, and about 75 high school students from the state of Kentucky present. NCBPS session included ''How to get into Graduate School'', ''How to Survive in Graduate School'', and a Panel on ''Opportunities for Physics Graduates.'' The report by AIP: ''Survey of Participants of the 12th Annual NCBPS'' is included in the Proceedings.

  8. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (16th, Rochester, New York, October 12-14, 1989).

    ERIC Educational Resources Information Center

    Hayes, Laurie Schultz, Ed.

    Based on the theme of recruiting, tenuring, and promoting technical communication faculty, this proceedings presents the agenda for the 1989 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC), a report on the annual business meeting, and a proposal to create a CPTSC Program Review Board. Appendixes present…

  9. Modulators for the S-band test linac at DESY

    SciTech Connect

    Bieler, M.; Choroba, S.; Hameister, J.; Lewin, H.

    1995-07-05

    The development of adequate modulators for high peak power klystrons is one of the focus points for linear collider R&D programs. For the DESY/THD S-band linear collider study 150 MW rf-pulse power at 50 Hz repetition rate and 3 {mu}s pulse duration is required [1]. Two different modulator schemes are under investigation. One is the conventional line type pulser, using a pulse forming network and a step up transformer, the other one is a hard tube pulser, using a dc power source at the full klystron voltage and a switch tube. This paper is focused on the modulator development for the S-band Test Linac at DESY. After a short overview over the test linac and a brief description of the 150 MW S-band klystron the circuitry of the line type pulse (LTP) is given. A hard tube pulser (HTP), which switches the high voltage directly from a storage capacitor to the klystron, has been built up at DESY. Circuitry and the results of the commissioning of the switch tube are reported. {copyright} {ital 1995} {ital American} {ital Institute} {ital of} {ital Physics}.

  10. Highlights of the annual scientific meeting of the 22nd congress of the European Society of Musculoskeletal Radiology (ESSR) 2015.

    PubMed

    Sellon, E; Grainger, A J; Robinson, P

    2016-01-01

    The meeting included a larger-than-usual number of scientific presentations covering a wide range of MSK topics, with new information related to imaging findings, imaging techniques, and interventional procedures. A large number of electronic posters were also available for review by the meeting participants, significantly adding to the educational content of the meeting. These are still available for review on the EPOS database via the ESSR website. The 23rd annual congress of the ESSR will be held in Zurich on June 9-11, 2016 where the main topic will be the knee and ankle. PMID:26385784

  11. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (24th, Austin, Texas, October 16-18, 1997).

    ERIC Educational Resources Information Center

    Council for Programs in Technical and Scientific Communication.

    Based on the theme of connections in technical and scientific communication, this proceedings presents 47 papers delivered at the 1997 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into 10 sections: (1) Theoretical Connections; (2) Legal and Ethical Connections;…

  12. An Evaluation of the North Carolina Annual Report on School Violence: Scientific Realism in Practice.

    ERIC Educational Resources Information Center

    Carruthers, William L.; Stacey, Dennis

    To analyze perceptions of what constitutes a safe school. different perceptions of what constitutes a safe school, an assessment of the first 4 years of North Carolina's Annual Report on School Violence (ARSV) is reported here. The ARSV is a collection of data on specific acts of violence occurring on school property. Data on acts of violence were…

  13. Institute for Scientific Computing Research Annual Report for Fiscal Year 2003

    SciTech Connect

    Keyes, D; McGraw, J

    2004-02-12

    The University Relations Program (URP) encourages collaborative research between Lawrence Livermore National Laboratory (LLNL) and the University of California campuses. The Institute for Scientific Computing Research (ISCR) actively participates in such collaborative research, and this report details the Fiscal Year 2003 projects jointly served by URP and ISCR.

  14. 1993 Annual report on scientific programs: A broad research program on the sciences of complexity

    SciTech Connect

    1993-12-31

    This report provides a summary of many of the research projects completed by the Santa Fe Institute (SFI) during 1993. These research efforts continue to focus on two general areas: the study of, and search for, underlying scientific principles governing complex adaptive systems, and the exploration of new theories of computation that incorporate natural mechanisms of adaptation (mutation, genetics, evolution).

  15. Nye County Nuclear Waste Repository Project Office independent scientific investigations program annual report, May 1997--April 1998

    SciTech Connect

    1998-07-01

    This annual summary report, prepared by the Nye County Nuclear Waste Repository Project Office (NWRPO), summarizes the activities that were performed during the period from May 1, 1997 to April 30, 1998. These activities were conducted in support of the Independent Scientific Investigation Program (ISIP) of Nye County at the Yucca Mountain Site (YMS). The Nye County NWRPO is responsible for protecting the health and safety of the Nye County residents. NWRPO`s on-site representative is responsible for designing and implementing the Independent Scientific Investigation Program (ISIP). Major objectives of the ISIP include: Investigating key issues related to conceptual design and performance of the repository that can have major impact on human health, safety, and the environment; identifying areas not being addressed adequately by the Department of Energy (DOE). Nye County has identified several key scientific issues of concern that may affect repository design and performance which were not being adequately addressed by DOE. Nye County has been conducting its own independent study to evaluate the significance of these issues. This report summarizes the results of monitoring from two boreholes and the Exploratory Studies Facility (ESF) tunnel that have been instrumented by Nye County since March and April of 1995. The preliminary data and interpretations presented in this report do not constitute and should not be considered as the official position of Nye County. The ISIP presently includes borehole and tunnel instrumentation, monitoring, data analysis, and numerical modeling activities to address the concerns of Nye County.

  16. Deep inelastic events containing two forward jets at DESY HERA

    SciTech Connect

    Kwiecinski, J.; Lewis, C.A.; Martin, A.D.

    1998-01-01

    We use the Balitskij-Fadin-Kuraev-Lipatov (BFKL) equation to calculate the rate of deep inelastic scattering events containing two forward jets (adjacent to the proton remnants) at DESY HERA. We compare the production of two forward jets with that of only one forward jet (the {open_quotes}Mueller{close_quotes} process). We obtain a stable prediction for this two to one jet ratio, which may serve as a measure of the BFKL vertex function. {copyright} {ital 1997} {ital The American Physical Society}

  17. Seventy sixth scientific assembly and annual meeting of the Radiological Society of North America

    SciTech Connect

    Not Available

    1990-01-01

    The RSNA Program Committee has again assembled a fine selection of scientific paper presentations from the over 2,800 abstracts that were submitted this year. The final program offers a total of 1,130 papers in 12 subspecialties and divided among the nine time slots during the week. The subspecialties covered are: Cardiovascular Radiology; Gastrointestinal Radiology; General Radiology; Genitourinary Radiology; Neuroradiology/Head and Neck; Nuclear Medicine; Pediatric Radiology; Physics; Musculoskeletal Radiology; Therapeutic Radiology and Radiobiology and Ultrasound.

  18. Annual review of selected dental literature: report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry.

    PubMed

    Jendresen, M D; Allen, E P; Bayne, S C; Donovan, T E; Hansson, T L; Klooster, J; Preston, J D

    1993-07-01

    The annual review of selected dental literature this year cites 384 published papers and reports. This year's review contains more editorial comment than reviews of years passed. New data on the biological responses to materials is emphasized in several sections. Observations on new compounds able to prevent plaque formation are presented. Clinically relevant advances in knowledge concerning the etching of different tooth structures are reported along with the effect of etching procedures on the dental pulp. Evaluation of periodontal diseases in all age groups is a topic. Limitations of current diagnostic techniques in periodontal disease, temporomandibular disorders, and implant therapy are included. There are new views on the use of dental amalgam. The future use of dental mercury is predicted. Interest in new ceramic systems is indicated as the demand for esthetics continues. Clinical information is emphasized over scientific information throughout this year's review. PMID:8366458

  19. How to write research papers and grants: 2011 Asian Pacific Society for Respirology Annual Scientific Meeting Postgraduate Session.

    PubMed

    Eastwood, Peter R; Naughton, Matthew T; Calverley, Peter; Zeng, Guangqiao; Beasley, Richard; Robinson, Bruce; Lee, Y C Gary

    2012-07-01

    This review article summarizes the content of a series of interrelated workshop presentations from the Annual Scientific Meeting of the Asian Pacific Society of Respirology held in Shanghai in November, 2011. The article describes tips and strategies for writing research papers and research grant applications and includes discussion of: the role of pulmonologists in research; the debates around the use of the journal impact factor; tips for writing manuscripts and publishing research in high-impact journals; how journals assess manuscripts and the most common reasons editors reject manuscripts; how to write grant applications and what grant panels look for in successful proposals; and how to undertake research in resource-limited countries. PMID:22452595

  20. Institute for scientific computing research;fiscal year 1999 annual report

    SciTech Connect

    Keyes, D

    2000-03-28

    Large-scale scientific computation, and all of the disciplines that support it and help to validate it, have been placed at the focus of Lawrence Livermore National Laboratory by the Accelerated Strategic Computing Initiative (ASCI). The Laboratory operates the computer with the highest peak performance in the world and has undertaken some of the largest and most compute-intensive simulations ever performed. Computers at the architectural extremes, however, are notoriously difficult to use efficiently. Even such successes as the Laboratory's two Bell Prizes awarded in November 1999 only emphasize the need for much better ways of interacting with the results of large-scale simulations. Advances in scientific computing research have, therefore, never been more vital to the core missions of the Laboratory than at present. Computational science is evolving so rapidly along every one of its research fronts that to remain on the leading edge, the Laboratory must engage researchers at many academic centers of excellence. In FY 1999, the Institute for Scientific Computing Research (ISCR) has expanded the Laboratory's bridge to the academic community in the form of collaborative subcontracts, visiting faculty, student internships, a workshop, and a very active seminar series. ISCR research participants are integrated almost seamlessly with the Laboratory's Center for Applied Scientific Computing (CASC), which, in turn, addresses computational challenges arising throughout the Laboratory. Administratively, the ISCR flourishes under the Laboratory's University Relations Program (URP). Together with the other four Institutes of the URP, it must navigate a course that allows the Laboratory to benefit from academic exchanges while preserving national security. Although FY 1999 brought more than its share of challenges to the operation of an academic-like research enterprise within the context of a national security laboratory, the results declare the challenges well met and well

  1. The European XFEL Free Electron Laser at DESY

    ScienceCinema

    Weise, Hans [Deutsches Elektronen-Synchrotron, Germany

    2009-09-01

    The European X-ray Free-Electron laser Facility (XFEL) is going to be built in an international collaboration at the Deutsches Elektronen-Synchrotron (DESY), Germany, and the Technical Design Report was published in 2006. The official project is expected for summer 2007. This new facility will offer photon beams at wavelengths as short as 1 angstrom with highest peak brilliance being more than 100 million times higher than present day synchrotron radiation sources. The radiation has a high degree of transverse coherence and the pulse duration is reduced from {approx}100 picoseconds (typ. for SR light sources) down to the {approx}10 femtosecond time domain. The overall layout of the XFEL will be described. This includes the envisaged operation parameters for the linear accelerator using superconducting TESLA technology. The complete design is based on the actually operated FLASH free-electron laser at DESY. Experience with the operation during first long user runs at wavelengths from 30 to 13 nm will be described in detail.

  2. CPTSC 2001: Managing Change and Growth in Technical and Scientific Communication. Proceedings of the Annual Conference of the Council for Programs in Technical and Scientific Communication (28th, Pittsburgh, Pennsylvania, October 11-13, 2001).

    ERIC Educational Resources Information Center

    Maylath, Bruce, Ed.

    This proceedings presents 43 papers delivered at the 2001 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings include the following: "Act IV: On Being Less Invisible" (Bill Karis); "Building a Community of Professional Communicators by Mapping Needs and Assets" (Stuart Blythe);…

  3. Publication rates of manuscript presentations at the American College of Foot and Ankle Surgeons Annual Scientific Conference between 1999 and 2008.

    PubMed

    Roukis, Thomas S

    2011-01-01

    Publication is the ultimate desired end point of scientific research. However, oral manuscript presentations of research studies are often referenced in textbooks, journal articles, and industry white papers, and, as a result, influence treatment care plans. No data exist for the actual publication rate of podiatric foot and ankle surgery oral manuscript presentations. Therefore, the objective of this study was to determine the actual publication rates of oral manuscript presentations at the American College of Foot and Ankle Surgeons (ACFAS) Annual Scientific Conference over 10 years. Print or electronic media for the ACFAS Annual Scientific Conference official program between 1999 and 2008 were obtained. Each year's official program was hand searched for any oral manuscript presentation, and, when identified, the title and authors were individually searched through electronic internet-based search engines to determine whether an oral manuscript presentation had been followed by publication of a full-text article. Additionally, pertinent journals were hand searched for potential articles. A total of 67.5% (139/206) oral manuscript presentations were ultimately published in 1 of 12 medical journals in a mean of 14.5 months. All journals except one (91.7%) represented peer-reviewed journals. The publication rate of oral manuscript presentations at the ACFAS Annual Scientific Conference is similar to or greater than orthopaedic subspecialties, including foot and ankle surgery, publication rates. Based on the above, attendees of the ACFAS Annual Scientific Conference should be aware that the majority of oral manuscript material presented at the ACFAS Annual Scientific Conference can be considered as accurate because they survive the rigors of the peer-review process more than two thirds of the time. PMID:21549618

  4. 1991 Annual report on scientific programs: A broad research program on the sciences of complexity

    SciTech Connect

    Not Available

    1991-12-31

    1991 was continued rapid growth for the Santa Fe Institute (SFI) as it broadened its interdisciplinary research into the organization, evolution and operation of complex systems and sought deeply the principles underlying their dynamic behavior. Research on complex systems--the focus of work at SFI--involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex behavior range upwards from proteins and DNA through cells and evolutionary systems to human societies. Research models exhibiting complexity include nonlinear equations, spin glasses, cellular automata, genetic algorithms, classifier systems, and an array of other computational models. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simples components, (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy), and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions. The importance of understanding such systems in enormous: many of the most serious challenges facing humanity--e.g., environmental sustainability, economic stability, the control of disease--as well as many of the hardest scientific questions--e.g., protein folding, the distinction between self and non-self in the immune system, the nature of intelligence, the origin of life--require deep understanding of complex systems.

  5. 1991 Annual report on scientific programs: A broad research program on the sciences of complexity

    SciTech Connect

    Not Available

    1991-01-01

    1991 was continued rapid growth for the Santa Fe Institute (SFI) as it broadened its interdisciplinary research into the organization, evolution and operation of complex systems and sought deeply the principles underlying their dynamic behavior. Research on complex systems--the focus of work at SFI--involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex behavior range upwards from proteins and DNA through cells and evolutionary systems to human societies. Research models exhibiting complexity include nonlinear equations, spin glasses, cellular automata, genetic algorithms, classifier systems, and an array of other computational models. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simples components, (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy), and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions. The importance of understanding such systems in enormous: many of the most serious challenges facing humanity--e.g., environmental sustainability, economic stability, the control of disease--as well as many of the hardest scientific questions--e.g., protein folding, the distinction between self and non-self in the immune system, the nature of intelligence, the origin of life--require deep understanding of complex systems.

  6. The Dark Energy Spectroscopic Instrument (DESI): The Spectrographs

    NASA Astrophysics Data System (ADS)

    Edelstein, Jerry; DESI Collaboration

    2015-01-01

    The Dark Energy Spectroscopic Instrument (DESI) will conduct a large-area galaxy and quasi-stellar object redshift survey from the Mayall Telescope. It includes of ten spectrographs each recording 500 simultaneous object spectra collected by 5,000 positioned optical fibers in the focal plane of an 8-square degree telescope corrector. The spectrographs use dichroic filters to divide light into three optical channels that together cover the 360 - 980 nm pass band with a spectral resolution of 2,000 to 5,100. Each channel includes a volume phase holographic grating (VPHG) and a 5-element camera that images spectra onto a cryostatic detector. We describe the spectrograph design and predicted performance and the production of the first spectrograph's optical elements.

  7. A first calibration study for PINGU at DESY

    SciTech Connect

    Shanidze, R.; Collaboration: IceCube-PINGU Collaboration

    2014-11-18

    PINGU, the Precision IceCube Next Generation Upgrade, aims at lowering the neutrino detection threshold of the IceCube neutrino telescope to a few GeV by adding new in-fill strings to the existing IceCube/DeepCore array. The main goal of the upgrade is to provide sensitivity to the neutrino mass hierarchy utilizing atmospheric neutrinos. Precision reconstruction of the neutrino direction and energy, which is a prerequisite for the determination of the mass hierarchy, requires accurate in-situ calibration and monitoring of the PINGU digital optical modules (PDOMs) and high-level control of systematic effects like those caused by uncertainties in the optical ice properties and sensitivity of the PDOM in ice. These proceedings present an early status of calibration studies for PINGU performed at DESY.

  8. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (19th, Boise, Idaho, October 8-10, 1992).

    ERIC Educational Resources Information Center

    Riordan, Daniel G., Ed.

    Based on the theme of broadening the base of academic, industrial and professional connections, this proceedings presents papers delivered at the annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into four sections: Models for Connecting Academia, Industries, and the…

  9. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (17th, San Diego, California, October 11-13, 1990).

    ERIC Educational Resources Information Center

    Zappen, James P., Ed.; Katz, Susan, Ed.

    Based on the theme of assessment, this proceedings presents papers and discussions from the annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Three papers in the proceedings discussing curricula are: "Model(s) for Educating Professional Communicators" (Marilyn M. Cooper); "Summary of Discussion of…

  10. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (14th, Orlando, Florida, October 7-9, 1987).

    ERIC Educational Resources Information Center

    Geonetta, Sam C., Ed.

    Based on the notion of "reaching out," this proceedings presents papers from the annual meeting of the Council for Programs in Technical and Scientific Communication. Papers in the proceedings are: "Southern Tech's Technical Writing Certificate" (William S. Pfeiffer); "Reach Out and Quack Someone" (Daniel R. Jones); "Reaching Out: A Rationale for…

  11. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (18th, Cincinnati, Ohio, October 10-12, 1991).

    ERIC Educational Resources Information Center

    Zappen, James P., Ed.; Katz, Susan, Ed.

    Based on the theme of issues, questions, and controversies in program development and review, this proceedings presents papers delivered at the annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into four sections: Benchmarks for Quality: Developing Criteria for…

  12. Merits of online electrochemistry liquid sample desorption electrospray ionization mass spectrometry (EC/LS DESI MS).

    PubMed

    Looi, Wen Donq; Brown, Blake; Chamand, Laura; Brajter-Toth, Anna

    2016-03-01

    A new online electrochemistry/liquid sample desorption electrospray ionization mass spectrometry (EC/LS DESI MS) system with a simple electrochemical thin-layer flow-through cell was developed and tested using N,N-dimethyl-p-phenylenediamine (DMPA) as a model probe. Although oxidation of DMPA is observed as a result of ionization of LS in positive ion mode LS DESI, application of voltage to the online electrochemical (EC) cell in EC/LS DESI MS increases yields of oxidation products. An advantage of LS DESI MS is its sensitivity in aqueous electrolyte solutions, which improves efficiency of electrochemical reactions in EC/LS DESI MS. In highly conductive low pH aqueous buffer solutions, oxidation efficiency is close to 100 %. EC/ESI MS typically requires mixed aqueous/organic solvents and low electrolyte concentrations for efficient ionization in MS, limiting efficiency of electrochemistry online with MS. Independently, the results verify higher electrochemical oxidation efficiency during positive mode ESI than during LS DESI. Graphical abstract Detection of DMPA oxidation in online electrochemical cell with EC/LS DESI MS. PMID:26886744

  13. Detecting Cheatgrass on the Colorado Plateau using Landsat data: A tutorial for the DESI software

    USGS Publications Warehouse

    Kokaly, Raymond F.

    2011-01-01

    Invasive plant species disrupt native ecosystems and cause economic harm to public lands. In this report, an example of applying the Detection of Early Season Invasives software to mapping cheatgrass infestations is given. A discussion of each step of the DESI process is given, including selection of Landsat images. Tutorial data, covering a semi-arid area in southern Utah, are distributed with this report. Tips on deriving the inputs required to run DESI are provided. An approach for evaluating and adjusting detection parameters by examining interim products of DESI is discussed.

  14. Meeting Highlights of the 11th Annual Scientific Sessions of the Society for Cardiovascular Magnetic Resonance, Los Angeles, February 1–3, 2008

    PubMed Central

    2008-01-01

    This paper features the most interesting presentations and discussions of the 2008 Annual Sessions of the Society for Cardiovascular Magnetic Resonance, which were held in Los Angeles from February 1 to 3, 2008. With more than 1100 attendees, this was the largest of the SCMR meetings ever. Among this year's highlights were scientific reports on CMR-based risk assessment, non-contrast tissue characterization, 3 T data, and interventional CMR. PMID:19128420

  15. Proceedings of the 24th Day of Scientific lectures and 20th Annual Meeting of the National Society of Black Physicists

    SciTech Connect

    Jackson, K.H; Carwell, H.V.

    1999-11-29

    The National Society of Black Physicists will hold its Twentieth annual meeting and its XXIIII Day of Scientific Lectures at Lawrence Berkeley National Laboratory on March 27th - 30th, 1997. The meeting provides a major opportunity for African American physicists and students to present their current research and discuss issues germane to the constituency. It is therefore crucial to have the broadest cross-section of the membership at each meeting. The Lawrence Berkeley National Laboratory was chosen as the site of the 20th annual meeting because of its historical significance to Physics (being one of the first national laboratories in the United States) and the laboratories continuing support of the goals and objectives of the society.

  16. Level of clinical evidence presented at the International Society for Hip Arthroscopy Annual Scientific Meeting over 5 years (2010-2014).

    PubMed

    Kay, Jeffrey; de Sa, Darren; Shallow, Scott; Simunovic, Nicole; Safran, Marc R; Philippon, Marc J; Ayeni, Olufemi R

    2015-12-01

    The International Society for Hip Arthroscopy (ISHA) Annual Scientific Meeting is at the forefront of informing today's orthopaedic surgeons and society of the rapid advances in the exponentially growing field of hip arthroscopy. The purpose of this study was to evaluate and observe any trends in the level of clinical evidence in the papers and posters presented at the ISHA Annual Scientific Meeting from 2010 to 2014. The online abstracts of the paper and poster presentations presented at the ISHA Annual Scientific Meetings were independently evaluated by two reviewers (582 total resulting presentations). Two reviewers screened these results for clinical studies and graded the quality of evidence from level I (i.e. randomized trials) to IV (i.e. case series) based on the American Academy of Orthopaedic Surgeons classification system. Four hundred and twenty-eight presentations met the inclusion criteria and were evaluated. Overall, 10.1% of the presentations were level I, 12.8% were level II, 30.1% were level III and 47.0% were level IV evidence. Over time, from 2010 to 2014, we observed an increase in the percentage of level II paper presentations, an increase in the proportion of level III poster presentations, and a decrease in the proportion of both level IV paper and poster presentations. Significant non-random improvement in the level of evidence presented was noted for the poster presentations (P = 0.012) but not for the paper presentations (P = 0.61) over the study period. Statistical trends demonstrate ISHA's increased awareness and commitment to presenting higher quality evidence as the availability of this evidence increases. PMID:27011857

  17. Level of clinical evidence presented at the International Society for Hip Arthroscopy Annual Scientific Meeting over 5 years (2010–2014)

    PubMed Central

    Kay, Jeffrey; de SA, Darren; Shallow, Scott; Simunovic, Nicole; Safran, Marc R.; Philippon, Marc J.; Ayeni, Olufemi R.

    2015-01-01

    The International Society for Hip Arthroscopy (ISHA) Annual Scientific Meeting is at the forefront of informing today’s orthopaedic surgeons and society of the rapid advances in the exponentially growing field of hip arthroscopy. The purpose of this study was to evaluate and observe any trends in the level of clinical evidence in the papers and posters presented at the ISHA Annual Scientific Meeting from 2010 to 2014. The online abstracts of the paper and poster presentations presented at the ISHA Annual Scientific Meetings were independently evaluated by two reviewers (582 total resulting presentations). Two reviewers screened these results for clinical studies and graded the quality of evidence from level I (i.e. randomized trials) to IV (i.e. case series) based on the American Academy of Orthopaedic Surgeons classification system. Four hundred and twenty-eight presentations met the inclusion criteria and were evaluated. Overall, 10.1% of the presentations were level I, 12.8% were level II, 30.1% were level III and 47.0% were level IV evidence. Over time, from 2010 to 2014, we observed an increase in the percentage of level II paper presentations, an increase in the proportion of level III poster presentations, and a decrease in the proportion of both level IV paper and poster presentations. Significant non-random improvement in the level of evidence presented was noted for the poster presentations (P = 0.012) but not for the paper presentations (P = 0.61) over the study period. Statistical trends demonstrate ISHA’s increased awareness and commitment to presenting higher quality evidence as the availability of this evidence increases. PMID:27011857

  18. Meeting report: British Society for Research on Ageing (BSRA) annual scientific meeting 2012, Aston University, Birmingham, 3rd to 4th July 2012

    PubMed Central

    2013-01-01

    The focus of the British Society for Research on Ageing (BSRA) annual scientific meeting 2012 was aging mechanisms and mitigants. The themes covered included epigenetics, stem cells and regeneration, aging pathways and molecules, the aging bladder and bowel, as well as updates from the New Dynamics of Ageing (NDA) programme. The topics incorporated new directions for staple aging research in caloric restriction (CR), inflammation, immunesenescence, neurodegeneration, homeostasis and stress resistance, as well as newer research areas such as bioengineering of tissues, including the internal anal sphincter and thymus. PMID:24472617

  19. Data preservation for the HERA experiments at DESY using dCache technology

    NASA Astrophysics Data System (ADS)

    Krücker, Dirk; Schwank, Karsten; Fuhrmann, Patrick; Lewendel, Birgit; South, David M.

    2015-12-01

    We report on the status of the data preservation project at DESY for the HERA experiments and present the latest design of the storage which is a central element for bit- preservation. The HEP experiments based at the HERA accelerator at DESY collected large and unique datasets during the period from 1992 to 2007. As part of the ongoing DPHEP data preservation efforts at DESY, these datasets must be transferred into storage systems that keep the data available for ongoing studies and guarantee safe long term access. To achieve a high level of reliability, we use the dCache distributed storage solution and make use of its replication capabilities and tape interfaces. We also investigate a recently introduced Small File Service that allows for the fully automatic creation of tape friendly container files.

  20. Abstracts for the 59th Annual Scientific Meeting (November 2011) by American Society of Cytopathology (ASC) at Baltimore, MD, USA

    PubMed Central

    2011-01-01

    These are peer-reviewed poster-platform submissions finalized by the Scientific Program Committee. A total of 153 abstracts (14 Platforms [PP1 through PP14] & 139 Posters [1 through 139]) were selected from 161 submissions to be considered for presentation during November 4 – 8, 2011, at the Hilton Baltimore Hotel, to pathologists, cytopathologists, cytotechnologists, residents, fellows, students, and other members of cytopathology-related medical and scientific fields.

  1. The effect of electrospray solvent composition on desorption electrospray ionisation (DESI) efficiency and spatial resolution.

    PubMed

    Green, F M; Salter, T L; Gilmore, I S; Stokes, P; O'Connor, G

    2010-04-01

    In desorption electrospray ionisation (DESI) the interaction between the electrospray and the surface is key to two important analytical parameters, the spatial resolution and the sensitivity. We evaluate the effect of the electrospray solvent type, organic solvent fraction with water, analyte solubility and substrate wettability on DESI erosion diameter and material transferral into useful ion signal. To do this five amino acids, glycine, alanine, valine, leucine and phenylalanine are prepared as thin films on three substrates, UV/ozone treated glass, glass and polytetrafluoroethylene (PTFE). Four different solvents, acetonitrile (ACN), methanol (MeOH), ethanol (EtOH) and propan-2-ol (IPA), are used with organic solvent fractions with water varying from 0.1 to 1. These model systems allow the solubility or wettability to be kept constant as other parameters are varied. Additionally, comparison with electrospray ionisation (ESI) allows effects of ionisation efficiency to be determined. It is shown that the DESI efficiency is linearly dependent on the solubility (for these materials at least) and for analytes with solubilities below 1.5 g kg(-1), additional strategies may be required for DESI to be effective. We show that the DESI erosion diameter improves linearly with organic solvent fraction, with an organic solvent fraction of 0.9 instead of 0.5 leading to a 2 fold improvement. Furthermore, this leads to a 35 fold increase in DESI efficiency, defined as the molecular ion yield per unit area. It is shown that these improvements correlate with smaller droplet sizes rather than surface wetting or ionisation. PMID:20349538

  2. Qualitative analysis of seized cocaine samples using desorption electrospray ionization- mass spectrometry (DESI-MS).

    PubMed

    Stojanovska, Natasha; Tahtouh, Mark; Kelly, Tamsin; Beavis, Alison; Fu, Shanlin

    2015-05-01

    Desorption electrospray ionization - mass spectrometry (DESI-MS) is a useful technique for the qualitative analysis of compounds found in seized drug material. In this study, DESI-MS was utilized in the screening analysis of illicit cocaine samples. The technique was also applied to the geographical origin determination of these samples. The limit of detection was determined to be 24.3 µg (or 3.47 µg/mm(2) ) and the analysis time was less than 1 minute per sample. The intra-day and inter-day precision for the detection of cocaine was 11 % and 42 %, respectively; therefore the quantitative data provided by DESI-MS was limited in its use for accurate determination of cocaine concentration in a sample. Using the quadrupole time-of-flight (QTOF) mass spectrometer, the presence of cocaine and impurities detected were confirmed by accurate tandem MS data. The qualitative chemical profiles obtained using DESI-MS were compared to two popular analysis techniques, GC-MS and LC-MS. The effects of a range of adulterants including caffeine, procaine, levamisole, lignocaine, paracetamol, and atropine on the detectability of cocaine were also investigated. It was found that the addition of these adulterants in a cocaine sample did not prevent the detection of the analyte itself (there was slight enhancement in some samples), which was useful in drug detection. The detection of truxillines in the seized samples by DESI-MS aided in the preliminary determination of geographical origin, i.e., Bolivian, Peruvian or Colombian leaf origin. The application of DESI-MS to the qualitative analysis and screening of seized cocaine samples demonstrates the potential and applicability of the technique to the fast chemical profiling of illicit samples. PMID:24943809

  3. Forensic applications of desorption electrospray ionisation mass spectrometry (DESI-MS).

    PubMed

    Morelato, Marie; Beavis, Alison; Kirkbride, Paul; Roux, Claude

    2013-03-10

    Desorption electrospray ionisation mass spectrometry (DESI-MS) is an emerging analytical technique that enables in situ mass spectrometric analysis of specimens under ambient conditions. It has been successfully applied to a large range of forensically relevant materials. This review assesses and highlights forensic applications of DESI-MS including the analysis and detection of illicit drugs, explosives, chemical warfare agents, inks and documents, fingermarks, gunshot residues and drugs of abuse in urine and plasma specimens. The minimal specimen preparation required for analysis and the sensitivity of detection achieved offer great advantages, especially in the field of forensic science. PMID:23498998

  4. A Report on the 30th Annual Conference of the International Association of Scientific and Technological University Libraries (IATUL)

    ERIC Educational Resources Information Center

    Tripathi, Manorama

    2010-01-01

    Purpose: The paper aims to report on the 30th IATUL Annual Conference held in Leuven, Belgium, 1-4 June, 2009. Design/methodology/approach: The paper summarises the major themes of the conference as well as giving some specific details of developments at the Indira Gandhi National Open University in India, which supplement the author's…

  5. Reactive DESI-MS imaging of biological tissues with dicationic ion-pairing compounds.

    PubMed

    Lostun, Dragos; Perez, Consuelo J; Licence, Peter; Barrett, David A; Ifa, Demian R

    2015-03-17

    This work illustrates reactive desorption electrospray ionization mass spectrometry (DESI-MS) with a stable dication on biological tissues. Rat brain and zebra fish tissues were investigated with reactive DESI-MS in which the dictation forms a stable bond with biological tissue fatty acids and lipids. Tandem mass spectrometry (MS/MS) was used to characterize the dication (DC9) and to identify linked lipid-dication compounds formed. The fragment m/z 85 common to both DC9 fragmentation and DC9-lipid fragmentation was used to confirm that DC9 is indeed bonded with the lipids. Lipid signals in the range of m/z 250-350 and phosphoethanolamines (PE) m/z 700-800 observed in negative ion mode were also detected in positive ion mode with reactive DESI-MS with enhanced signal intensity. Reactive DESI-MS imaging in positive ion mode of rat brain and zebra fish tissues allowed enhanced detection of compounds commonly observed in the negative ion mode. PMID:25710577

  6. DETECTION OF INTACT PROTEINS WITH DESI-MS: APPLICATION TO MICROORGANISM BIOMARKER DETECTION

    Technology Transfer Automated Retrieval System (TEKTRAN)

    DESI-MS was evaluated with proteins that range in molecular weight from 12 KDa to 66 KDa. Lyophilized protein samples were rehydrated with water, deposited on Plexiglas, and dried. In some experiments buckminsterfullerene (bucky ball, C60) was used as an additive to the nebulizing gas. Optimized ...

  7. "Loops and Legs in Quantum Field Theory", 12th DESY Workshop on Elementary Particle Physics

    NASA Astrophysics Data System (ADS)

    The bi-annual international conference "Loops and Legs in Quantum Field Theory" has been held at Weimar, Germany, from April 27 to May 02, 2014. It has been the 12th conference of this series, started in 1992. The main focus of the conference are precision calculations of multi- loop and multi-leg processes in elementary particle physics for processes at present and future high-energy facilities within and beyond the Standard Model. At present many physics questions studied deal with processes at the LHC and future facilities like the ILC. A growing number of contributions deals with important developments in the field of computational technologies and algorithmic methods, including large-scale computer algebra, efficient methods to compute large numbers of Feynman diagrams, analytic summation and integration methods of various kinds, new related function spaces, precise numerical methods and Monte Carlo simulations. The present conference has been attended by more than 110 participants from all over the world, presenting more than 75 contributions, most of which have been written up for these pro- ceedings. The present volume demonstrates in an impressive way the enormous development of the field during the last few years, reaching the level of 5-loop calculations in QCD and a like- wise impressive development in massive next-to-leading order and next-to-next-to-leading order processes. Computer algebraic and numerical calculations require terabyte storage and many CPU years, even after intense parallelization, to obtain state-of-the-art theoretical predictions. The city of Weimar gave a suitable frame to the conference, with its rich history, especially in literature, music, arts, and architecture. Goethe, Schiller, Wieland, Herder, Bach and Liszt lived there and created many of their masterpieces. The many young participants signal that our field is prosperous and faces an exciting future. The conference hotel "Kaiserin Augusta" offered a warm hospitality and

  8. Publication rates of poster presentations at the American College of Foot and Ankle Surgeons annual scientific conference between 1999 and 2008.

    PubMed

    Abicht, Bradley P; Donnenwerth, Michael P; Borkosky, Sara L; Plovanich, Elizabeth J; Roukis, Thomas S

    2012-01-01

    Publication is the desired end point of scientific research. Ultimately, it is desired that research presented in poster format at a scientific conference will be developed into a report and become published in a peer-reviewed scientific journal. Moreover, poster presentations of research studies are often referenced and, as a result, influence treatment care plans. No data exist for the actual publication rate of podiatric foot and ankle surgery poster presentations. Therefore, the objective of the present study was to determine the actual publication rates of poster presentations at the American College of Foot and Ankle Surgeons (ACFAS) annual scientific conference (ASC) during a 10-year period. Print or electronic media for the ACFAS ASC official program from 1999 to 2008 were obtained. Each year's official program was manually searched for any poster presentation and, when identified, the authors and title were individually searched using Internet-based search engines to determine whether a poster presentation had been followed by publication. Of the 825 posters, 198 (24%) poster presentations were ultimately published in 1 of 32 medical journals within a weighted mean of 17.6 months. Of the 32 journals, 25 (78.1%) represented peer-reviewed journals. The publication rate of poster presentations at the ACFAS ASC was less than that of oral manuscripts presented at the same meeting during the same period and was also less than the orthopedic subspecialty poster presentation publication rates. Therefore, attendees of the ACFAS ASC should be aware that only a few of the posters presented at the ACFAS ASC will be valid because they will not survive the rigors of publication 76% of the time. Additionally, more stringent selection criteria should be used so that the selected poster presentations can ultimately withstand the publication process. PMID:22196458

  9. 18th Annual Scientific Meeting of the International Society for Biological Therapy of Cancer. 30 October-2 November 2003, Bethesda, Maryland, USA.

    PubMed

    Marincola, Francesco M; Wang, Ena; Atkins, Michael B

    2004-01-01

    The 18th Annual Scientific Meeting of the International Society for Biological Therapy of Cancer (iSBTc) was held at the Hyatt Regency, Bethesda, MD, close to the National Institutes of Health (NIH) campus. The meeting was organised on behalf of the society by Neil Berinstein from Aventis Pasteur, Toronto, Canada, Janice P Dutcher from Our Lady of Mercy Medical Center, Bronx, NY and Francesco M Marincola from the NIH, Bethesda, MD. The 2003 meeting included 57 oral presentations and > 100 poster presentations. There were > 800 registrants to the Annual Meeting and the multiple satellite symposia. The iSBTc, formerly the Society of Biological Therapy (SBT), was founded by R Oldham in 1984. Its membership has been rapidly growing of late, with > 500 members at present. The purpose of the iSBTc is to bring together those diverse individuals actively investigating biologic agents and biological response modifiers in the treatment of cancer, including clinicians and basic scientists from industry, government and academia. The President of the Society is Dr Michael B Atkins from Beth Israel Deaconess Medical Center, Boston, MA and the Vice President is Ulrich Keilholz from UKBF, Free University Berlin, Germany. PMID:14680473

  10. Publication rates of abstracts presented at annual scientific meetings: how does the Royal Australian and New Zealand College of Radiologists compare?

    PubMed

    Bydder, Sean A; Joseph, David J; Spry, Nigel A

    2004-03-01

    The abstract to publication ratio (APR) is a measure of the quality of scientific meetings. The aim of the present study was to determine the publication rate of abstracts presented at annual Royal Australian and New Zealand College of Radiologists (RANZCR) conferences, and to identify the publishing journals. All free paper research abstracts (oral or poster) presented by RANZCR radiologists, radiation oncologists and trainees at the four consecutive meetings between 1996 and 1999 were identified retrospectively from conference programmes. The PubMed database (http://www.ncbi.nlm.nih.gov/PubMed/) was searched to determine whether or not the abstract had been published as a full paper. Of the 480 free paper research abstracts, 168 (35%) had been published as full articles. The overall abstract to publication ratio for radiology was 29% and for radiation oncology was 41%. Papers were published in a variety of journals but Australasian Radiology accounted for 27%. The mean time between presentation and publication was 16.5 months (median 17 months). These overall abstract to publication ratios are lower than those reported for overseas-based meetings in each respective area. Guidelines to scientific committees could increase the APR by more rigorous selection of abstracts. Future research should look at barriers to the publication of research findings, and identify ways to assist the publication process. PMID:15027917

  11. Design considerations and analysis of potential applications of a high power ultraviolet FEL at the TESLA test facility at DESY

    NASA Astrophysics Data System (ADS)

    Pagani, C.; Saldin, E. L.; Schneidmiller, E. A.; Yurkov, M. V.

    1999-02-01

    A possibility of constructing a high power ultraviolet free electron laser at the TESLA test facility at DESY is discussed. The proposed facility consists of a tunable master oscillator (P av˜10 mW, P peak˜10 kW, λ≃200-350 nm) and an FEL amplifier with a tapered undulator. The average and peak radiation power at the exit of the FEL amplifier is about 7 kW and 220 GW, respectively. Installation of such a facility can significantly extend scientific potential of the TESLA test facility. The UV free electron laser can be used to construct a polarized, monochromatic gamma-source with the ultimate yield up to 10 12 gamma-quanta per second and the maximal energy of about 100 MeV. An intensive gamma-source can also form the base for constructing the test facility for the TESLA positron generation system. Another accelerator application of the proposed facility is verification of the main technical solutions for the laser and the optical system to be used in the gamma-gamma option of the TESLA collider. A high average power UV laser is also promising for industrial applications.

  12. Gesellschaft fuer angewandte Mathematik und Mechanik, Scientific Annual Meeting, Technische Universitaet Wien, Vienna, Austria, Apr. 5-9, 1988, Reports

    NASA Astrophysics Data System (ADS)

    Various papers on applied mathematics and mechanics are presented. The general topics considered include: numerical treatment of implicit differential equations and differential algebraic systems; software for scientific calculation; structural analysis and simulation; stochastic methods; biomathematics; interpolation and approximation; quadrature; optimization; methods in operations research; enclosures for linear and nonlinear equations; enclosures for functional equations; ordinary differential equations and dynamical systems; ordinary differential and difference equations; and numerics of stiff differential equations. Also addressed are: waves, analysis, applications, and numerics in partial differential equations; large systems of linear equations; multigrid methods; iterative processes in applied function theory; discrete mathematics and informatics; fundamentals, special methods, and shells in FEM; beams and special applications; fundamentals, solid mechanics, and fluid mechanics in BEM.

  13. Improved DESI-MS Performance using Edge Sampling and aRotational Sample Stage

    SciTech Connect

    Kertesz, Vilmos; Van Berkel, Gary J

    2008-01-01

    The position of the surface to be analyzed relative to the sampling orifice or capillary into the mass spectrometer has been known to dramatically affect the observed signal levels in desorption electrospray ionization mass spectrometry (DESIMS). In analyses of sample spots on planar surfaces, DESI-MS signal intensities as much as five times greater were routinely observed when the bottom of the sampling capillary was appropriately positioned beneath the surface plane ( edge sampling") compared to when the capillary just touched the surface. To take advantage of the optimum "edge sampling" geometry and to maximize the number of samples that could be analyzed in this configuration, a rotational sample stage was integrated into a typical DESI-MS setup. The rapid quantitative determination of caffeine in two diet sport drinks (Diet Turbo Tea, Speed Stack Grape) spiked with an isotopically labeled internal standard demonstrated the utility of this approach.

  14. An advanced draft genome assembly of a desi type chickpea (Cicer arietinum L.)

    PubMed Central

    Parween, Sabiha; Nawaz, Kashif; Roy, Riti; Pole, Anil K.; Venkata Suresh, B.; Misra, Gopal; Jain, Mukesh; Yadav, Gitanjali; Parida, Swarup K.; Tyagi, Akhilesh K.; Bhatia, Sabhyata; Chattopadhyay, Debasis

    2015-01-01

    Chickpea (Cicer arietinum L.) is an important pulse legume crop. We previously reported a draft genome assembly of the desi chickpea cultivar ICC 4958. Here we report an advanced version of the ICC 4958 genome assembly (version 2.0) generated using additional sequence data and an improved genetic map. This resulted in 2.7-fold increase in the length of the pseudomolecules and substantial reduction of sequence gaps. The genome assembly covered more than 94% of the estimated gene space and predicted the presence of 30,257 protein-coding genes including 2230 and 133 genes encoding potential transcription factors (TF) and resistance gene homologs, respectively. Gene expression analysis identified several TF and chickpea-specific genes with tissue-specific expression and displayed functional diversification of the paralogous genes. Pairwise comparison of pseudomolecules in the desi (ICC 4958) and the earlier reported kabuli (CDC Frontier) chickpea assemblies showed an extensive local collinearity with incongruity in the placement of large sequence blocks along the linkage groups, apparently due to use of different genetic maps. Single nucleotide polymorphism (SNP)-based mining of intra-specific polymorphism identified more than four thousand SNPs differentiating a desi group and a kabuli group of chickpea genotypes. PMID:26259924

  15. DESI-MS/MS of Chemical Warfare Agents and Related Compounds

    NASA Astrophysics Data System (ADS)

    D'Agostino, Paul A.

    Solid phase microextraction (SPME) fibers were used to headspace ­sample chemical warfare agents and their hydrolysis products from glass vials and glass vials containing spiked media, including Dacron swabs, office carpet, paper and fabric. The interface of the Z-spray source was modified to permit safe introduction of the SPME fibers for desorption electrospray ionization mass spectrometric (DESI-MS) analysis. A "dip and shoot" method was also developed for the rapid sampling and DESI-MS analysis of chemical warfare agents and their hydrolysis products in liquid samples. Sampling was performed by simply dipping fused silica, stainless steel or SPME tips into the organic or aqueous samples. Replicate analyses were completed within several minutes under ambient conditions with no sample pre-treatment, resulting in a significant increase in sample throughput. The developed sample handling and analysis method was applied to the determination of chemical warfare agent content in samples containing unknown chemical and/or biological warfare agents. Ottawa sand was spiked with sulfur mustard, extracted with water and autoclaved to ensure sterility. Sulfur mustard was completely hydrolysed during the extraction/autoclave step and thiodiglycol was identified by DESI-MS, with analyses generally being completed within 1 min using the "dip and shoot" method.

  16. Science, Technology, and Communication: Program Design in the Past, Present, and Future. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (26th, Santa Fe, New Mexico, October 14-16, 1999).

    ERIC Educational Resources Information Center

    Rude, Carolyn, Ed.

    Based on the theme of the past, present, and future of science, technology, and communication programs, this proceedings presents 49 papers delivered at the 1999 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into 12 subsections: The Shape of Programs: Past,…

  17. Models for Strategic Program Development. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (27th, Menomonie, Wisconsin, October 19-21, 2000).

    ERIC Educational Resources Information Center

    Maylath, Bruce, Ed.

    This document presents 48 papers delivered at the 2000 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into 14 subsections: (1) Keynote Presentation: "Global Classroom Project (T. K. Herrington); (2) Opening Session Address: "What Industry Looks for in Technical…

  18. Critical Interfaces for Engineers and Scientists, 4 Appraisals. Proceedings of the Annual Joint Meeting of the Engineering Manpower Commission of Engineers Joint Council and the Scientific Manpower Commission, New York, May 18, 1967.

    ERIC Educational Resources Information Center

    Alden, John D.

    Contained in this booklet are the speeches given at the annual joint meeting of the Engineering Manpower Commission and the Scientific Manpower Commission. Each dealt with some problem aspect of the engineer-scientist interface. The presentation by Rear Admiral W. C. Hushing of the U. S. Navy was entitled "The Impact of High Performance Science…

  19. The Ecology, the Environment, and the Evolution of Technical Communication. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (25th, Lewes, Delaware, October 15-17, 1998).

    ERIC Educational Resources Information Center

    Council for Programs in Technical and Scientific Communication.

    This proceedings presents 40 papers delivered at the 1998 annual meeting of the Council for Programs in Technical and Scientific Communication (CPTSC). Papers in the proceedings are divided into sections on the Ecology of Technology; Environmental Shifts; and Evolving Perspectives. Representative papers in the proceedings include: "Mixing Oil and…

  20. Detection of saccharides by reactive desorption electrospray ionization (DESI) using modified phenylboronic acids

    NASA Astrophysics Data System (ADS)

    Zhang, Yun; Chen, Hao

    2010-01-01

    We have reported previously a method for the detection of sugars via in-situ derivatization with phenylboronic acid PhB(OH)2 using reactive desorption electrospray ionization (DESI, Chen et al., Chem. Commun. (2006) 597-599). The present study describes an improved method that employs modified phenylboronic acids including 3-nitrophenylboronic acid and N-methyl-4-pyridineboronic acid iodide. In contrast to using PhB(OH)2, enhanced sensitivity of using 3-nitrophenylboronic acid was observed due to the stabilization of the resulting boronate ester anion by the electron-withdrawing nitro group and the limit of detections (LODs) for glucose in water using 3-nitrophenylbornic acid and phenylboronic acid were determined to be 0.11 mM and 0.40 mM, respectively. In the case of N-methyl-4-pyridineboronic acid iodide, the corresponding LOD is 6.9 [mu]M and the higher sensitivity obtained is attributed to the efficient ionization of both the reactive DESI reagent and reaction product since the precursor acid with a quaternary ammonium group is pre-charged. In this case, additional important features are found: (i) unlike using phenylboronic acid or 3-nitrophenylbornic acid, the experiment, performed in the positive ion mode, is applicable to neutral and acidic saccharide solutions, facilitating the analysis of biological fluids without the need to adjust pH; (ii) simply by changing the spray solvent from water to acetonitrile, the method can be used for direct glucose analyses of both urine and serum samples via online desalting, due to the low solubility of salts of these biofluids in the sprayed organic solvent; (iii) in comparison with other sugar derivatizing reagents such as the Girard's reagent T, the N-methyl-4-pyridineboronic acid iodide shows higher reactivity in the reactive DESI; and (iv) the ions of saccharide DESI reaction products undergo extensive ring or glycosidic bond cleavage upon CID, a feature that might be useful in the structure elucidation of

  1. Differential response of kabuli and desi chickpea genotypes toward inoculation with PGPR in different soils

    PubMed Central

    Imran, Asma; Mirza, Muhammad S.; Shah, Tariq M.; Malik, Kauser A.; Hafeez, Fauzia Y.

    2015-01-01

    Pakistan is among top three chickpea producing countries but the crop is usually grown on marginal lands without irrigation and fertilizer application which significantly hampers its yield. Soil fertility and inoculation with beneficial rhizobacteria play a key role in nodulation and yield of legumes. Four kabuli and six desi chickpea genotypes were, therefore, evaluated for inoculation response with IAA-producing Ochrobactrum ciceri Ca-34T and nitrogen fixing Mesorhizobium ciceri TAL-1148 in single and co-inoculation in two soils. The soil type 1 was previously unplanted marginal soil having low organic matter, P and N contents compared to soil type 2 which was a fertile routinely legume-cultivated soil. The effect of soil fertility status was pronounced and fertile soil on average, produced 31% more nodules, 62% more biomass and 111% grain yield than marginal soil. Inoculation either with O. ciceri alone or its co-inoculation with M. ciceri produced on average higher nodules (42%), biomass (31%), grains yield (64%) and harvest index (72%) in both chickpea genotypes over non-inoculated controls in both soils. Soil 1 showed maximum relative effectiveness of Ca-34T inoculation for kabuli genotypes while soil 2 showed for desi genotypes except B8/02. Desi genotype B8/02 in soil type 1 and Pb-2008 in soil type 2 showed significant yield increase as compared to respective un-inoculated controls. Across bacterial inoculation treatments, grain yield was positively correlated to growth and yield contributing parameters (r = 0.294* to 0.838*** for desi and r = 0.388* to 0.857** for kabuli). PCA and CAT-PCA analyses clearly showed a site-specific response of genotype x bacterial inoculation. Furthermore, the inoculated bacterial strains were able to persist in the rhizosphere showing colonization on root and within nodules. Present study shows that plant growth promoting rhizobacteria (PGPR) inoculation should be integrated with national chickpea breading program in

  2. Monitoring of changes in lipid profiles during PLK1 knockdown in cancer cells using DESI MS.

    PubMed

    Jayashree, Balasubramanyam; Srimany, Amitava; Jayaraman, Srinidhi; Bhutra, Anjali; Janakiraman, Narayanan; Chitipothu, Srujana; Krishnakumar, Subramanian; Baddireddi, Lakshmi Subhadra; Elchuri, Sailaja; Pradeep, Thalappil

    2016-08-01

    The importance of the polo-like kinase 1 (PLK1) gene is increasing substantially both as a biomarker and as a target for highly specific cancer therapy. This is due to its involvement in multiple points of cell progression and carcinogenesis. PLK1 inhibitors' efficacy in treating human cancers has been limited due to the lack of a specific targeting strategy. Here, we describe a method of targeted downregulation of PLK1 in cancer cells and the concomitant rapid detection of surface lipidomic perturbations using desorption electrospray ionization mass spectrometry (DESI MS). The efficient delivery of siRNA targeting PLK1 gene selectively to the cancer cells is achieved by targeting overexpressed cell surface epithelial cell adhesion molecule (EpCAM) by the EpDT3 aptamer. The chimeric aptamer (EpDT3-siPLK1) showed the knockdown of PLK1 gene expression and PLK1 protein levels by quantitative PCR and western blotting, respectively. The abundant surface lipids, phosphatidylcholines (PCs), such as PC(32:1) (m/z 754.6), PC(34:1) (m/z 782.6), and PC(36:2) (m/z 808.6), were highly expressed in MCF-7 and WERI-RB1 cancer cells compared to normal MIO-M1 cells and they were observed using DESI MS. These overexpressed cell surface lipids in the cancer cells were downregulated upon the treatment of EpDT3-siPLK1 chimera indicating a novel role of PLK1 to regulate surface lipid expression in addition to the efficient selective cancer targeting ability. Our results indicate that DESI MS has a potential ability to rapidly monitor aptamer-mediated cancer therapy and accelerate the drug discovery process. Graphical abstract Binding of aptamer chimera to the cells and changes in lipid profile. PMID:27277815

  3. Analysis of DESY-Flash LLRF Measurements for the ILC Heavy Beam Loading Test

    SciTech Connect

    Cancelo, Gustavo; Chase, Brian; Davidsaver, Michael; Carwardine, J.; Simrock, Stefan; Ayvazyan, Valeri; Grecki, Mariusz; Matsumoto, Toshihiro; Michizono, Shinichiro; /KEK, Tsukuba

    2009-06-01

    In September 2008 the DESY-FLASH accelerator was run with up to 550, 3 nano-coulomb bunches at 5 Hz repetition rate. This test is part of a longer-term study aimed at validating ILC parameters by operation as close as possible to ILC beam currents and RF gradients. The present paper reports on the analysis that has been done in order to understand the RF control system performance during this test. Actual klystron power requirements and beam stability are evaluated with heavy beam loading conditions. Results include suggested improvements for upcoming tests in 2009.

  4. Transatlantic Transport of Fermilab 3.9 GHZ Cryomodule to DESY

    SciTech Connect

    McGee, M.W.; Grimm, C.; Olis, D.; Schappert, Warren; /Fermilab

    2009-05-01

    In an exchange of technology agreement, Fermilab has built and delivered a 3.9 GHz (3rd harmonic) cryomodule to Deutsches Elektron-Synchrotron (DESY) Laboratory to be installed in the TTF/FLASH beamline. Transport to Hamburg, Germany was completed via a combination of flatbed air ride truck and commercial aircraft, while minimizing transition or handling points. Initially, destructive testing of fragile components, transport and corresponding alignment stability studies were performed in order to assess the risk associated with transatlantic travel of a fully assembled cryomodule. Data logged triaxial acceleration results of the transport with a comparison to the transport study predicted values are presented.

  5. Blotting Assisted by Heating and Solvent Extraction for DESI-MS Imaging

    NASA Astrophysics Data System (ADS)

    Cabral, Elaine C.; Mirabelli, Mario F.; Perez, Consuelo J.; Ifa, Demian R.

    2013-06-01

    Imprints of potato sprout ( Solanum tuberosum L.), gingko leaves (Gingko biloba L. ) and strawberries (Fragaria x ananassa Duch. ) were successfully imaged by desorption electrospray ionization mass spectrometry (DESI-MS) on TLC plates through blotting assisted by heating and/or solvent extraction. Ion images showing the distribution of significant compounds such as glycoalkaloid toxins in potato sprout, ginkgolic acids and flavonoids in ginkgo leaves, and sugars and anthocyanidin in strawberry were obtained. Practical implications of this work include analysis of a wide range of irregular or soft materials by different imprinting conditions without requiring the addition of matrices or use of specific kinds of surfaces.

  6. The National Analysis Facility at DESY - status and use cases by the participating experiments

    NASA Astrophysics Data System (ADS)

    Aplin, S.; Ehrenfeld, W.; Haupt, A.; Kemp, Y.; Langenbruch, C.; Leffhalm, K.; Lucaci-Timoce, A.; Stadie, H.

    2011-12-01

    The German National Analysis Facility (NAF) was set up at DESY, starting end of 2007 in the context of the Helmholtz Alliance "Physics at the Terascale". The NAF complements the DESY and the German Grid resources, and hence offers users from the German HEP institutes the best possible environment for data analysis. In the first part, the key aspects and components of the NAF are briefly presented with an emphasis on recent improvements. In the second part, the use cases of the three participating LHC experiments, ATLAS, CMS and LHCb, will be presented. Differences and commonalities in the usage of the NAF will be shown. Special emphasis will be placed on the usage of PROOF, whose usage on the NAF has been pioneered by CMS. It is now adapted by ATLAS. The third part will concentrate on how the NAF was used for detector optimisation studies in the preparation of one of the ILC Lol's (ILD 2009), as well as how CALICE uses the NAF for the analysis of their data taken in several test beam experiments performed for detector R & D. Finally, future developments of the NAF are presented.

  7. SINBAD-The accelerator R&D facility under construction at DESY

    NASA Astrophysics Data System (ADS)

    Dorda, U.; Assmann, R.; Brinkmann, R.; Flöttmann, K.; Hartl, I.; Hüning, M.; Kärtner, F.; Fallahi, A.; Marchetti, B.; Nie, Y.; Osterhoff, J.; Schlarb, H.; Zhu, J.; Maier, A. R.

    2016-09-01

    The SINBAD facility (Short INnovative Bunches and Accelerators at DESY) is a long-term dedicated accelerator research and development facility currently under construction at DESY. It will be located in the premises of the old DORIS accelerator complex and host multiple independent experiments cost-effectively accessing the same central infrastructure like a central high power laser. With the removal of the old DORIS accelerator being completed, the refurbishment of the technical infrastructure is currently starting up. The presently ongoing conversion of the area into the SINBAD facility and the currently foreseen layout is described. The first experiment will use a compact S-band linac for the production of ultra-short bunches at hundred MeV. Once established, one of the main usages will be to externally inject electrons into a laser-driven plasma wakefield accelerator to boost the energy to GeV-level while maintaining a usable beam quality, ultimately aiming to drive an FEL. The second experiment already under planning is the setup of an attosecond radiation source with advanced technology. Further usage of the available space and infrastructure is revised and national and international collaborations are being established.

  8. Advances in Large Grain/Single Crystal SC Resonators at DESY

    SciTech Connect

    W. Singer; A. Brinkmann; A. Ermakov; J. Iversen; G. Kreps; A. Matheisen; D. Proch; D. Reschke; X. Singer; M. Spiwek; H. We; P. Kneisel; M. Pekeler

    2007-08-01

    The main aim of the DESY large grain R&D program is to check whether this option is reasonable to apply for fabrication of ca. 1'000 XFEL cavities. Two aspects are being pursued. On one hand the basic material investigation, on the other hand the material availability, fabrication and preparation procedure. Several single cell large grain cavities of TESLA shape have been fabricated and tested. The best accelerating gradients of 41 MV/m was measured on electropolished cavity. First large grain nine-cell cavities worldwide have been produced under contract of DESY with ACCEL Instruments Co. All three cavities fulfil the XFEL specification already in first RF test after only BCP (Buffered Chemical Polishing) treatment and 800 degrees C annealing. Accelerating gradient of 27 - 29 MV/m was reached. A fabrication method of single crystal cavity of ILC like shape was proposed. A single cell single crystal cavity was build at the company ACCEL. Accelerating gradient of 37.5 MV/m reached after only 112 microns BCP and in situ baking 120 degrees C for 6 hrs with the quality factor higher as 2x1010. The developed method can be extended on fabrication of multi cell single crystal cavities.

  9. Analysis of Metabolic Changes in Plant Pathosystems by Imprint Imaging DESI-MS

    NASA Astrophysics Data System (ADS)

    Tata, Alessandra; Perez, Consuelo J.; Hamid, Tanam S.; Bayfield, Mark A.; Ifa, Demian R.

    2015-04-01

    The response of plants to microbial pathogens is based on the production of secondary metabolites. The complexity of plant-pathogen interactions makes their understanding a challenging task for metabolomic studies requiring powerful analytical approaches. In this paper, the ability of ambient mass spectrometry to provide a snapshot of plant metabolic response to pathogen invasion was tested. The fluctuations of glycoalkaloids present in sprouted potatoes infected by the phytopathogen Pythium ultimum were monitored by imprint imaging desorption electrospray ionization mass spectrometry (DESI-MS). After 8 d from the inoculation, a decrease of the relative abundance of potato glycoalkaloids α-solanine ( m/z 706) and α-chaconine ( m/z 722) was observed, whereas the relative intensity of solanidine ( m/z 398), solasodenone ( m/z 412), solanaviol ( m/z 430), solasodiene ( m/z 396), solaspiralidine ( m/z 428), γ-solanine/γ-chaconine ( m/z 560) , β-solanine ( m/z 706), and β-chaconine ( m/z 722) increased. The progression of the disease, expressed by the development of brown necrotic lesions on the potato, led to the further decrease of all the glycoalkaloid metabolites. Therefore, the applicability of imprint imaging DESI-MS in studying the plant metabolic changes in a simple pathosystem was demonstrated with minimal sample preparation.

  10. Upgrade of the H^--injection system at the DESY proton Linac III

    NASA Astrophysics Data System (ADS)

    Kleffner, C.-M.; Holtkamp, N.; Jacobs, G.; Nagl, M.; Deitinghoff, H.; Paramonov, V.

    1997-05-01

    In the near future an upgrade of the injection system of the proton linac at DESY is foreseen. Two different types of H^--sources are operated at DESY. The new rf-driven volume source is cesium free. On a long-term basis this source is planned to replace the operating magnetron source. For reasons of reliability of the proton linac and further developments of sources parallel operation of two sources should be possible at the the Alvarez linac. Each source has a separate RFQ to accelerate the ions to an energy of 750 keV. A new transport line with one dipole, 8 quadrupoles and one intermediate buncher was designed to match the beam between both RFQs and the Alvarez linac. The codes COPPOC and TRANSPORT were used for determining the length of the transport line and the parameters of the dipole and the buncher. Because of the high currents of more than 20 mA the estimate of the space charge forces is of special interest. The macro-particle-code PARMTRA takes into account the particle-to-particle electric forces among all particles. The properties of the beam line have been studied in connection with the effects of the final beam quality after acceleration with the 50 MeV Alvarez linac.

  11. HPTLC/DESI-MS Imaging of Tryptic Protein Digests Separated in Two Dimensions

    SciTech Connect

    Pasilis, Sofie P; Kertesz, Vilmos; Van Berkel, Gary J; Schulz, Michael; Schorcht, Susanne

    2008-01-01

    Desorption electrospray ionization mass spectrometry (DESI-MS) was demonstrated as a method to detect and identify peptides from two-dimensional separations of cytochrome c and myoglobin tryptic digests on ProteoChrom HPTLC Cellulose sheets. Data-dependent tandem mass spectra were acquired during lane scans across the TLC plates. Peptides and the corresponding proteins were identified using a protein database search software. Two-dimensional distributions of identified peptides were mapped for each separated protein digest. Sequence coverages for cytochrome c and myoglobin were 81% and 74%, respectively. These compared well to those determined using the more standard HPLC/ESI-MS/MS approach (89% and 84%, respectively). Preliminary results show that use of more sensitive instrumentation has the potential for improved detection of peptides with low Rf values and improvement in sequence coverage. However, less multiple charging and more sodiation were seen in HPTLC/DESI-MS spectra relative to HPLC/ESI-MS spectra, which can affect peptide identification by MS/MS. Methods to increase multiple charging and reduce the extent of sodiation are currently under investigation.

  12. DESI and other Dark Energy experiments in the era of neutrino mass measurements

    SciTech Connect

    Font-Ribera, Andreu; McDonald, Patrick; Mostek, Nick; Reid, Beth A.; Seo, Hee-Jong; Slosar, Anže E-mail: PVMcDonald@lbl.gov E-mail: BAReid@lbl.gov E-mail: anze@bnl.gov

    2014-05-01

    We present Fisher matrix projections for future cosmological parameter measurements, including neutrino masses, Dark Energy, curvature, modified gravity, the inflationary perturbation spectrum, non-Gaussianity, and dark radiation. We focus on DESI and generally redshift surveys (BOSS, HETDEX, eBOSS, Euclid, and WFIRST), but also include CMB (Planck) and weak gravitational lensing (DES and LSST) constraints. The goal is to present a consistent set of projections, for concrete experiments, which are otherwise scattered throughout many papers and proposals. We include neutrino mass as a free parameter in most projections, as it will inevitably be relevant — DESI and other experiments can measure the sum of neutrino masses to ∼ 0.02 eV or better, while the minimum possible sum is ∼ 0.06 eV. We note that constraints on Dark Energy are significantly degraded by the presence of neutrino mass uncertainty, especially when using galaxy clustering only as a probe of the BAO distance scale (because this introduces additional uncertainty in the background evolution after the CMB epoch). Using broadband galaxy power becomes relatively more powerful, and bigger gains are achieved by combining lensing survey constraints with redshift survey constraints. We do not try to be especially innovative, e.g., with complex treatments of potential systematic errors — these projections are intended as a straightforward baseline for comparison to more detailed analyses.

  13. Scientific Journalism in Armenia

    NASA Astrophysics Data System (ADS)

    Farmanyan, S. V.; Mickaelian, A. M.

    2015-07-01

    In the present study, the problems of scientific journalism and activities of Armenian science journalists are presented. Scientific journalism in the world, forms of its activities, Armenian Astronomical Society (ArAS) press-releases and their subjects, ArAS website "Mass Media News" section, annual and monthly calendars of astronomical events, and "Astghagitak" online journal are described. Most interesting astronomical subjects involved in scientific journalism, reasons for non-satisfactory science outreach and possible solutions are discussed.

  14. Review of R&D at DESY on ingot niobium for accelerators

    NASA Astrophysics Data System (ADS)

    Navitski, Aliaksandr; Sekutowicz, Jacek; Singer, Waldemar; Singer, Xenia

    2015-12-01

    An R&D program at DESY exploring the potential of the production of 1.3 GHz TESLA shape cavities from large grain or ingot niobium material has been carried out as a feasibility study for using ingot niobium material for the European X-ray Free-Electron Laser project. The most important issues like feasibility of the fabrication of niobium discs from ingots, material properties, cavity fabrication, treatment, and finally the cryogenic radiofrequency (RF) performance of the cavity in the accelerator modules are presented and discussed. At least 25% higher intrinsic quality factor comparing to conventional fine-grain niobium and high accelerating gradient of up to 45 MV/m have been demonstrated during the cryogenic RF tests both in the vertical cryostats and in a completely assembled accelerating cryo-module.

  15. Potential applications of the dielectric wakefield accelerators in the SINBAD facility at DESY

    NASA Astrophysics Data System (ADS)

    Nie, Y. C.; Assmann, R.; Dorda, U.; Marchetti, B.; Weikum, M.; Zhu, J.; Hüning, M.

    2016-09-01

    Short, high-brightness relativistic electron bunches can drive ultra-high wakefields in the dielectric wakefield accelerators (DWFAs). This effect can be used to generate high power THz coherent Cherenkov radiation, accelerate a witness bunch with gradient two or three orders of magnitude larger than that in the conventional RF linear accelerators, introduce energy modulation within the driving bunch itself, etc. The paper studies potential applications of the DWFAs in the SINBAD facility at DESY. The simulations show that the ultra-short relativistic bunches from the SINBAD injector ARES can excite accelerating wakefields with peak amplitudes as high as GV/m at THz frequencies in proper DWFA structures. In addition, it illustrates that the DWFA structure can serve as a dechirper to compensate the correlated energy spread of the bunches accelerated by the laser plasma wakefield accelerator.

  16. HARWI-II, The New High-Energy Beamline for Materials Science at HASYLAB/DESY

    SciTech Connect

    Beckmann, Felix; Lippmann, Thomas; Metge, Joachim; Dose, Thomas; Donath, Tilman; Schreyer, Andreas; Tischer, Markus; Liss, Klaus Dieter

    2004-05-12

    The GKSS Forschungszentrum Geesthacht, Germany, will setup a new high-energy beamline specialized for texture, strain and imaging measurements for materials science at the Hamburger Synchrotronstrahlungslabor HASYLAB of the Deutsches Elektronen-Synchrotron DESY. Four different experiments will be installed at the new wiggler HARWI-II. The high pressure cell will be run by the GFZ Potsdam, Germany, the high-energy diffractometer together with a microtomography camera will be run by the GKSS. A further station will allow space for the diffraction enhanced imaging setup. The optics will provide for a small white beam (0.5 mm x 0.5 mm) and a large monochromatic X-ray beam (50 mm x 10 mm) with an energy range of 20 to 250 keV.

  17. A VUV free electron laser at the TESLA test facility at DESY

    NASA Astrophysics Data System (ADS)

    Rossbach, J.; Tesla Fel Study Group

    1996-02-01

    We present the layout of a single pass free electron laser (FEL) to be driven by the TESLA Test Facility (TTF) currently under construction at DESY. The TTF is a test-bed for high-gradient, high efficiency superconducting acceleration sections for a future linear collider. Due to its unrivaled ability to sustain high beam quality during acceleration, a superconducting rf linac is considered the optimum choice to drive a FEL. We aim at a photon wavelength of λ = 6 nm utilizing the TTF after it has been extended to 1 GeV beam energy. Due to lack of mirrors and seed-lasers in this wavelength regime, a single pass FEL and self-amplified spontaneous emission (SASE) is considered. A first test is foreseen at a larger photon wavelength. The overall design as well as both electron and photon beam properties are discussed.

  18. Review of R&D at DESY on ingot niobium for accelerators

    SciTech Connect

    Navitski, Aliaksandr Sekutowicz, Jacek Singer, Waldemar Singer, Xenia

    2015-12-04

    An R&D program at DESY exploring the potential of the production of 1.3 GHz TESLA shape cavities from large grain or ingot niobium material has been carried out as a feasibility study for using ingot niobium material for the European X-ray Free-Electron Laser project. The most important issues like feasibility of the fabrication of niobium discs from ingots, material properties, cavity fabrication, treatment, and finally the cryogenic radiofrequency (RF) performance of the cavity in the accelerator modules are presented and discussed. At least 25% higher intrinsic quality factor comparing to conventional fine-grain niobium and high accelerating gradient of up to 45 MV/m have been demonstrated during the cryogenic RF tests both in the vertical cryostats and in a completely assembled accelerating cryo-module.

  19. A Combined Desorption Ionization by Charge Exchange (DICE) and Desorption Electrospray Ionization (DESI) Source for Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Chan, Chang-Ching; Bolgar, Mark S.; Miller, Scott A.; Attygalle, Athula B.

    2011-01-01

    A source that couples the desorption ionization by charge exchange (DICE) and desorption electrospray ionization (DESI) techniques together was demonstrated to broaden the range of compounds that can be analyzed in a single mass spectrometric experiment under ambient conditions. A tee union was used to mix the spray reagents into a partially immiscible blend before this mixture was passed through a conventional electrospray (ES) probe capillary. Using this technique, compounds that are ionized more efficiently by the DICE method and those that are ionized better with the DESI procedure could be analyzed simultaneously. For example, hydroquinone, which is not detected when subjected to DESI-MS in the positive-ion generation mode, or the sodium adduct of guaifenesin, which is not detected when examined by DICE-MS, could both be detected in one experiment when the two techniques were combined. The combined technique was able to generate the molecular ion, proton and metal adduct from the same compound. When coupled to a tandem mass spectrometer, the combined source enabled the generation of product ion spectra from the molecular ion and the [M + H]+ or [M + metal]+ ions of the same compound without the need to physically change the source from DICE to DESI. The ability to record CID spectra of both the molecular ion and adduct ions in a single mass spectrometric experiment adds a new dimension to the array of mass spectrometric methods available for structural studies.

  20. A combined desorption ionization by charge exchange (DICE) and desorption electrospray ionization (DESI) source for mass spectrometry.

    PubMed

    Chan, Chang-Ching; Bolgar, Mark S; Miller, Scott A; Attygalle, Athula B

    2011-01-01

    A source that couples the desorption ionization by charge exchange (DICE) and desorption electrospray ionization (DESI) techniques together was demonstrated to broaden the range of compounds that can be analyzed in a single mass spectrometric experiment under ambient conditions. A tee union was used to mix the spray reagents into a partially immiscible blend before this mixture was passed through a conventional electrospray (ES) probe capillary. Using this technique, compounds that are ionized more efficiently by the DICE method and those that are ionized better with the DESI procedure could be analyzed simultaneously. For example, hydroquinone, which is not detected when subjected to DESI-MS in the positive-ion generation mode, or the sodium adduct of guaifenesin, which is not detected when examined by DICE-MS, could both be detected in one experiment when the two techniques were combined. The combined technique was able to generate the molecular ion, proton and metal adduct from the same compound. When coupled to a tandem mass spectrometer, the combined source enabled the generation of product ion spectra from the molecular ion and the [M + H](+) or [M + metal](+) ions of the same compound without the need to physically change the source from DICE to DESI. The ability to record CID spectra of both the molecular ion and adduct ions in a single mass spectrometric experiment adds a new dimension to the array of mass spectrometric methods available for structural studies. PMID:21472555

  1. A Comparison of DESI-MS and LC-MS for the Lipidomic Profiling of Human Cancer Tissue

    NASA Astrophysics Data System (ADS)

    Abbassi-Ghadi, Nima; Jones, Emrys A.; Gomez-Romero, Maria; Golf, Ottmar; Kumar, Sacheen; Huang, Juzheng; Kudo, Hiromi; Goldin, Rob D.; Hanna, George B.; Takats, Zoltan

    2016-02-01

    In this study, we make a direct comparison between desorption electrospray ionization-mass spectrometry (DESI-MS) and ultraperformance liquid chromatography-electrospray ionization-mass spectrometry (UPLC-ESI-MS) platforms for the profiling of glycerophospholipid (GPL) species in esophageal cancer tissue. In particular, we studied the similarities and differences in the range of GPLs detected and the congruency of their relative abundances as detected by each analytical platform. The main differences between mass spectra of the two modalities were found to be associated with the variance in adduct formation of common GPLs, rather than the presence of different GPL species. Phosphatidylcholines as formate adducts in UPLC-ESI-MS accounted for the majority of differences in negative ion mode and alkali metal adducts of phosphatidylcholines in DESI-MS for positive ion mode. Comparison of the relative abundance of GPLs, normalized to a common peak, revealed a correlation coefficient of 0.70 ( P < 0.001). The GPL profile detected by DESI-MS is congruent to UPLC-ESI-MS, which reaffirms the role of DESI-MS for lipidomic profiling and a potential premise for quantification.

  2. A Comparison of DESI-MS and LC-MS for the Lipidomic Profiling of Human Cancer Tissue.

    PubMed

    Abbassi-Ghadi, Nima; Jones, Emrys A; Gomez-Romero, Maria; Golf, Ottmar; Kumar, Sacheen; Huang, Juzheng; Kudo, Hiromi; Goldin, Rob D; Hanna, George B; Takats, Zoltan

    2016-02-01

    In this study, we make a direct comparison between desorption electrospray ionization-mass spectrometry (DESI-MS) and ultraperformance liquid chromatography-electrospray ionization-mass spectrometry (UPLC-ESI-MS) platforms for the profiling of glycerophospholipid (GPL) species in esophageal cancer tissue. In particular, we studied the similarities and differences in the range of GPLs detected and the congruency of their relative abundances as detected by each analytical platform. The main differences between mass spectra of the two modalities were found to be associated with the variance in adduct formation of common GPLs, rather than the presence of different GPL species. Phosphatidylcholines as formate adducts in UPLC-ESI-MS accounted for the majority of differences in negative ion mode and alkali metal adducts of phosphatidylcholines in DESI-MS for positive ion mode. Comparison of the relative abundance of GPLs, normalized to a common peak, revealed a correlation coefficient of 0.70 (P < 0.001). The GPL profile detected by DESI-MS is congruent to UPLC-ESI-MS, which reaffirms the role of DESI-MS for lipidomic profiling and a potential premise for quantification. PMID:26466600

  3. On-probe pyrolysis desorption ecectrospray ionization (DESI) mass spectrometry for the analysis of non-volatile pyrolysis products

    Technology Transfer Automated Retrieval System (TEKTRAN)

    An on-probe pyrolyzer has been constructed and interfaced with desorption electrospray ionization (DESI) mass spectrometry (MS) for the rapid analysis of non-volatile pyrolysis products. The detection and analysis of non-volatile pyrolysis products of peptides, proteins and the synthetic polymer pol...

  4. Prospects of Hybrid Plasma- and Radiofrequency-Based Electron Acceleration at DESY

    NASA Astrophysics Data System (ADS)

    Osterhoff, Jens; Gruener, Florian; Elsen, Eckhard; Floettmann, Klaus; Foster, Brian; Brinkmann, Reinhard; Schmidt, Bernhard; Schlarb, Holger; Stephan, Frank

    2012-10-01

    The field of particle acceleration in plasma wakes has seen remarkable progress in recent years. Accelerating gradients of more than 10 GV/m can now be readily achieved using either ultra-short intense laser pulses or particle beams as wake drivers. The demonstration of the first GeV electron beams and a general trend towards improved reproducibility, beam quality and control over the involved plasma processes has led to plasma-acceleration techniques beginning to draw considerable interest in the traditional accelerator community. As a consequence, DESY, Germany's leading accelerator center, has established a research program for plasma-based novel acceleration techniques with the goal of exploiting the synergetic combination of conventional and new accelerator technology. Such a concept offers an attractive pathway to study many mechanisms occurring in plasma-based accelerators, for example electron-beam-emittance evolution, extreme bunch compression, the controlled emission of betatron radiation, and staging of accelerating units. In addition, it is assumed that bypassing the difficult-to-master process of particle self-injection, which is utilized in all current laser-plasma acceleration schemes, will greatly enhance the reliability of such machines compared to the state-of-the-art.

  5. Properties of hadronic final states in diffractive deep inelastic ep scattering at DESY HERA

    NASA Astrophysics Data System (ADS)

    Chekanov, S.; Derrick, M.; Krakauer, D.; Magill, S.; Musgrave, B.; Pellegrino, A.; Repond, J.; Yoshida, R.; Mattingly, M. C.; Antonioli, P.; Bari, G.; Basile, M.; Bellagamba, L.; Boscherini, D.; Bruni, A.; Bruni, G.; Romeo, G. Cara; Cifarelli, L.; Cindolo, F.; Contin, A.; Corradi, M.; de Pasquale, S.; Giusti, P.; Iacobucci, G.; Levi, G.; Margotti, A.; Massam, T.; Nania, R.; Palmonari, F.; Pesci, A.; Sartorelli, G.; Zichichi, A.; Aghuzumtsyan, G.; Brock, I.; Goers, S.; Hartmann, H.; Hilger, E.; Irrgang, P.; Jakob, H.-P.; Kappes, A.; Katz, U. F.; Kerger, R.; Kind, O.; Paul, E.; Rautenberg, J.; Schnurbusch, H.; Stifutkin, A.; Tandler, J.; Voss, K. C.; Weber, A.; Wieber, H.; Bailey, D. S.; Brook, N. H.; Cole, J. E.; Foster, B.; Heath, G. P.; Heath, H. F.; Robins, S.; Rodrigues, E.; Scott, J.; Tapper, R. J.; Wing, M.; Capua, M.; Mastroberardino, A.; Schioppa, M.; Susinno, G.; Jeoung, H. Y.; Kim, J. Y.; Lee, J. H.; Lim, I. T.; Ma, K. J.; Pac, M. Y.; Caldwell, A.; Helbich, M.; Liu, W.; Liu, X.; Mellado, B.; Paganis, S.; Sampson, S.; Schmidke, W. B.; Sciulli, F.; Chwastowski, J.; Eskreys, A.; Figiel, J.; Klimek, K.; Olkiewicz, K.; Przybycień, M. B.; Stopa, P.; Zawiejski, L.; Bednarek, B.; Grabowska-Bold, I.; Jeleń, K.; Kisielewska, D.; Kowal, A. M.; Kowal, M.; Kowalski, T.; Mindur, B.; Przybycień, M.; Rulikowska-Zarȩbska, E.; Suszycki, L.; Szuba, D.; Szuba, J.; Kotański, A.; Bauerdick, L. A.; Behrens, U.; Borras, K.; Chiochia, V.; Crittenden, J.; Dannheim, D.; Desler, K.; Drews, G.; Fox-Murphy, A.; Fricke, U.; Geiser, A.; Goebel, F.; Göttlicher, P.; Graciani, R.; Haas, T.; Hain, W.; Hartner, G. F.; Hebbel, K.; Hillert, S.; Koch, W.; Kötz, U.; Kowalski, H.; Labes, H.; Löhr, B.; Mankel, R.; Martens, J.; Martínez, M.; Milite, M.; Moritz, M.; Notz, D.; Petrucci, M. C.; Polini, A.; Schneekloth, U.; Selonke, F.; Stonjek, S.; Wolf, G.; Wollmer, U.; Whitmore, J. J.; Wichmann, R.; Youngman, C.; Zeuner, W.; Coldewey, C.; Viani, A. Lopez-Duran; Meyer, A.; Schlenstedt, S.; Barbagli, G.; Gallo, E.; Pelfer, P. G.; Bamberger, A.; Benen, A.; Coppola, N.; Markun, P.; Raach, H.; Wölfle, S.; Bell, M.; Bussey, P. J.; Doyle, A. T.; Glasman, C.; Lee, S. W.; Lupi, A.; McCance, G. J.; Saxon, D. H.; Skillicorn, I. O.; Bodmann, B.; Gendner, N.; Holm, U.; Salehi, H.; Wick, K.; Yildirim, A.; Ziegler, A.; Carli, T.; Garfagnini, A.; Gialas, I.; Lohrmann, E.; Foudas, C.; Gonçalo, R.; Long, K. R.; Metlica, F.; Miller, D. B.; Tapper, A. D.; Walker, R.; Cloth, P.; Filges, D.; Kuze, M.; Nagano, K.; Tokushuku, K.; Yamada, S.; Yamazaki, Y.; Barakbaev, A. N.; Boos, E. G.; Pokrovskiy, N. S.; Zhautykov, B. O.; Ahn, S. H.; Lee, S. B.; Park, S. K.; Lim, H.; Son, D.; Barreiro, F.; García, G.; González, O.; Labarga, L.; del Peso, J.; Redondo, I.; Terrón, J.; Vázquez, M.; Barbi, M.; Bertolin, A.; Corriveau, F.; Ochs, A.; Padhi, S.; Stairs, D. G.; Tsurugai, T.; Antonov, A.; Bashkirov, V.; Danilov, P.; Dolgoshein, B. A.; Gladkov, D.; Sosnovtsev, V.; Suchkov, S.; Dementiev, R. K.; Ermolov, P. F.; Golubkov, Yu. A.; Katkov, I. I.; Khein, L. A.; Korotkova, N. A.; Korzhavina, I. A.; Kuzmin, V. A.; Levchenko, B. B.; Lukina, O. Yu.; Proskuryakov, A. S.; Shcheglova, L. M.; Solomin, A. N.; Vlasov, N. N.; Zotkin, S. A.; Bokel, C.; Engelen, J.; Grijpink, S.; Maddox, E.; Koffeman, E.; Kooijman, P.; Schagen, S.; Tassi, E.; Tiecke, H.; Tuning, N.; Velthuis, J. J.; Wiggers, L.; de Wolf, E.; Brümmer, N.; Bylsma, B.; Durkin, L. S.; Gilmore, J.; Ginsburg, C. M.; Kim, C. L.; Ling, T. Y.; Boogert, S.; Cooper-Sarkar, A. M.; Devenish, R. C.; Ferrando, J.; Große-Knetter, J.; Matsushita, T.; Rigby, M.; Ruske, O.; Sutton, M. R.; Walczak, R.; Brugnera, R.; Carlin, R.; Corso, F. Dal; Dusini, S.; Limentani, S.; Longhin, A.; Parenti, A.; Posocco, M.; Stanco, L.; Turcato, M.; Adamczyk, L.; Iannotti, L.; Oh, B. Y.; Saull, P. R.; Toothacker, W. S.; Iga, Y.; D'Agostini, G.; Marini, G.; Nigro, A.; Cormack, C.; Hart, J. C.; McCubbin, N. A.; Epperson, D.; Heusch, C.; Sadrozinski, H.; Seiden, A.; Williams, D. C.; Park, I. H.; Pavel, N.; Abramowicz, H.; Dagan, S.; Gabareen, A.; Kananov, S.; Kreisel, A.; Levy, A.; Abe, T.; Fusayasu, T.; Kohno, T.; Umemori, K.; Yamashita, T.; Hamatsu, R.; Hirose, T.; Inuzuka, M.; Kitamura, S.; Matsuzawa, K.; Nishimura, T.; Arneodo, M.; Cartiglia, N.; Cirio, R.; Costa, M.; Ferrero, M. I.; Maselli, S.; Monaco, V.; Peroni, C.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Bailey, D. C.; Fagerstroem, C.-P.; Galea, R.; Koop, T.; Levman, G. M.; Martin, J. F.; Mirea, A.; Sabetfakhri, A.; Butterworth, J. M.; Gwenlan, C.; Hall-Wilton, R.; Hayes, M. E.; Heaphy, E. A.; Jones, T. W.; Lane, J. B.; Lightwood, M. S.; West, B. J.; Ciborowski, J.; Ciesielski, R.; Grzelak, G.; Nowak, R. J.; Pawlak, J. M.; Smalska, B.; Tymieniecka, T.; Ukleja, A.; Ukleja, J.; Zakrzewski, J. A.; Żarnecki, A. F.; Adamus, M.; Plucinski, P.; Sztuk, J.; Eisenberg, Y.; Gladilin, L. K.; Hochman, D.; Karshon, U.; Breitweg, J.; Chapin, D.; Cross, R.; Kçira, D.; Lammers, S.; Reeder, D. D.; Savin, A. A.; Smith, W. H.; Deshpande, A.; Dhawan, S.; Hughes, V. W.; Straub, P. B.; Bhadra, S.; Catterall, C. D.; Frisken, W. R.; Khakzad, M.; Menary, S.

    2002-03-01

    Characteristics of the hadronic final state of diffractive deep inelastic scattering events ep-->eXp were studied in the kinematic range 4DESY ep collider HERA using an integrated luminosity of 13.8 pb-1. The events were tagged by identifying the diffractively scattered proton using the leading proton spectrometer. The properties of the hadronic final state X were studied in its center-of-mass frame using thrust, thrust angle, sphericity, energy flow, transverse energy flow, and ``seagull'' distributions. As the invariant mass of the system increases, the final state becomes more collimated, more aligned, and more asymmetric in the average transverse momentum with respect to the direction of the virtual photon. Comparisons of the properties of the hadronic final state with predictions from various Monte Carlo model generators suggest that the final state is dominated by qq&;g states at the parton level.

  6. Transatlantic transport of Fermilab 3.9 GHz cryomodule for TTF/FLASH to DESY

    SciTech Connect

    McGee, M.W.; Vocean, V.; Grimm, C.; Schappert, W.; /Fermilab

    2008-06-01

    In an exchange of technology agreement, Fermilab built and will deliver a 3.9 GHz (3rd harmonic) cryomodule to DESY to be installed in the TTF/FLASH beamline. This cryomodule delivery will involve a combination of flatbed air ride truck and commercial aircraft transport to Hamburg Germany. A description of the isolation and damping systems that maintain alignment during transport and protect fragile components is provided. Initially, transport and corresponding alignment stability studies were performed in order to assess the risk associated with transatlantic travel of a fully assembled cryomodule. Shock loads were applied to the cryomodule by using a coldmass mockup to prevent subjecting actual critical components (such as the cavities and input couplers) to excessive forces. Accumulative and peak shock loads were applied through over-the-road testing and using a pendulum hammer apparatus, respectively. Finite Element Analysis (FEA) studies were implemented to define location of instrumentation for transport studies and provide modal frequencies and shapes. Shock and vibration measurement results of transport studies and stabilization techniques are discussed.

  7. Studies on a VUV free electron laser at the TESLA Test Facility at DESY

    SciTech Connect

    Rossbach, J.

    1995-12-31

    The TESLA Test Facility (TTF) currently under construction at DESY is a test-bed for acceleration sections of a high-gradient, high efficiency superconducting linear collider. Due to ist unrivaled ability to sustain high beam quality during acceleration, a superconducting rf linac is considered the optimum choice to drive a Free Electron Laser (FEL). We aim at a photon wavelength of {lambda} = 6 manometer utilizing the TTF after is has been extended to 1 GeV beam energy. Due to lack of mirrors and seed-lasers in this wavelength regime, a single pass FEL and Self-Amplified-Spontaneous-Emission (SASE) is considered. A first test is foreseen at a larger photon wavelength. The overall design as well as both electron and photon beam properties will be discussed. To reach the desired photon wavelength, the main components that have to be added to the TTF are: (a) a low emittance rf gun including space charge compensation (b) a two stage bunch compressor increasing the peak bunch current from 100 A up to 2500 A (c) four more accelerating modules to achieve 1 GeV beam energy (d) a 25 m long undulator (period length 27 mm, peak field 0.5 T) The average brillance will be larger than 1-10{sup 22}photons/s/mm{sup 2}/mrad{sup 2}/0.1%. Each 800 {mu}s long pulse will contain up to 7200 equidistant bunches. The repetition frequency of the linac is 10 Hz.

  8. 21 CFR 330.12 - Status of over-the-counter (OTC) drugs previously reviewed under the Drug Efficacy Study (DESI).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... identical, similar and related products (21 CFR 310.6). Deferral of requirements is not appropriate for the... in the Federal Register of May 25, 1971 (36 FR 9475). (iii) Certain Insulin Preparations (DESI...

  9. 21 CFR 330.12 - Status of over-the-counter (OTC) drugs previously reviewed under the Drug Efficacy Study (DESI).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... identical, similar and related products (21 CFR 310.6). Deferral of requirements is not appropriate for the... in the Federal Register of May 25, 1971 (36 FR 9475). (iii) Certain Insulin Preparations (DESI...

  10. 21 CFR 330.12 - Status of over-the-counter (OTC) drugs previously reviewed under the Drug Efficacy Study (DESI).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... identical, similar and related products (21 CFR 310.6). Deferral of requirements is not appropriate for the... in the Federal Register of May 25, 1971 (36 FR 9475). (iii) Certain Insulin Preparations (DESI...

  11. 21 CFR 330.12 - Status of over-the-counter (OTC) drugs previously reviewed under the Drug Efficacy Study (DESI).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... identical, similar and related products (21 CFR 310.6). Deferral of requirements is not appropriate for the... in the Federal Register of May 25, 1971 (36 FR 9475). (iii) Certain Insulin Preparations (DESI...

  12. 21 CFR 330.12 - Status of over-the-counter (OTC) drugs previously reviewed under the Drug Efficacy Study (DESI).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... identical, similar and related products (21 CFR 310.6). Deferral of requirements is not appropriate for the... in the Federal Register of May 25, 1971 (36 FR 9475). (iii) Certain Insulin Preparations (DESI...

  13. Proceedings of the Annual Meeting of the Council for Programs in Technical and Scientific Communication (12th, Oxford, Ohio, February 13-15, 1985).

    ERIC Educational Resources Information Center

    Samuels, Marilyn Schauer, Ed.

    The papers in this proceedings of the Council for Programs in Technical and Scientific Communication (CPTSC) conference discuss collaboration with other disciplines, with business and industry, and with research foundations, reflecting the readiness to reach out that characterizes CPTSC in its second decade. Papers in the proceedings are:…

  14. FLASH, the Free-Electron Laser at DESY: Machine Performance and Recent Highlights from User Experiments

    NASA Astrophysics Data System (ADS)

    Wurth, Wilfried

    2010-03-01

    FLASH, the Free-Electron Laser at DESY in Hamburg is a world-wide unique facility delivering intense ultra-short coherent radiation pulses in the wavelength range between 47 and 6.8 nm. FLASH is a high-gain free-electron laser based on a superconducting linear accelerator currently running at 1GeV. Laser amplification and saturation in the so-called SASE (self-amplified spontaneous emission) mode is achieved with a single pass of the electron bunch through a 30m undulator. A machine upgrade which has been started recently will boost the energy to 1.2 GeV expanding the wavelength range to below 5nm. After the upgrade FLASH will also include the seeding experiment sFLASH where an external laser will overlap with the electron beam to seed the SASE process. First beam with the upgraded facility is expected in spring 2010. Since 2005 FLASH has been operating as a user facility serving a large variety of experiments. The unprecedented brilliance of the femtosecond coherent pulses in the extreme ultraviolet (XUV) and soft x-ray regime has been used to study nonlinear process in laser-matter interaction for atoms and molecules, to gain new insights in the properties of matter under extreme conditions and to perform single shot lens-less imaging of nano-sized objects. Furthermore, the pulse duration of less than 30 femtoseconds has allowed to gain new insights in ultrafast dynamics of matter. In the talk I will review machine performance and give examples of highlight experiments.

  15. Lipid dynamics in zebrafish embryonic development observed by DESI-MS imaging and nanoelectrospray-MS.

    PubMed

    Pirro, V; Guffey, S C; Sepúlveda, M S; Mahapatra, C T; Ferreira, C R; Jarmusch, A K; Cooks, R G

    2016-06-01

    The zebrafish Danio rerio is a model vertebrate organism for understanding biological mechanisms. Recent studies have explored using zebrafish as a model for lipid-related diseases, for in vivo fish bioassays, and for embryonic toxicity experiments. Mass spectrometry (MS) and MS imaging are established tools for lipid profiling and spatial mapping of biomolecules and offer rapid, sensitive, and simple analytical protocols for zebrafish analysis. When ambient ionization techniques are used, ions are generated in native environmental conditions, requiring neither sample preparation nor separation of molecules prior to MS. We used two direct MS techniques to describe the dynamics of the lipid profile during zebrafish embryonic development from 0 to 96 hours post-fertilization and to explore these analytical approaches as molecular diagnostic assays. Desorption electrospray ionization (DESI) MS imaging followed by nanoelectrospray (nESI) MS and tandem MS (MS/MS) were used in positive and negative ion modes, allowing the detection of a large variety of phosphatidylglycerols, phosphatidylcholines, phosphatidylinositols, free fatty acids, triacylglycerols, ubiquinone, squalene, and other lipids, and revealed information on the spatial distributions of lipids within the embryo and on lipid molecular structure. Differences were observed in the relative ion abundances of free fatty acids, triacylglycerols, and ubiquinone - essentially localized to the yolk - across developmental stages, whereas no relevant differences were found in the distribution of complex membrane glycerophospholipids, indicating conserved lipid constitution. Embryos exposed to trichloroethylene for 72 hours exhibited an altered lipid profile, indicating the potential utility of this technique for testing the effects of environmental contaminants. PMID:27120110

  16. Inspection of a Spherical Triple VLS-Grating for Self-Seeding of FLASH at DESY

    NASA Astrophysics Data System (ADS)

    Siewert, Frank; Lammert, Heiner; Reichardt, Gerd; Hahn, Ulrich; Treusch, Rolf; Reininger, Ruben

    2007-01-01

    To take benefit from the improved brilliance of the laser-like source, proposed beamlines at Free Electron Lasers (FEL) require optical elements of excellent precision, characterised by slope errors beyond the state of the art limit of 0.5μrad rms for plane and spherical shape. Part of the monochromator beamline for self-seeding at the vacuum-ultraviolet Free Electron Laser (FLASH) at DESY is a triple Variable Line Spacing (VLS) grating of spherical shape. The three grating structures on a common substrate will cover the wavelength range from 6.4 to 60nm The challenging specifications of these grating structures are characterised by a slope error of less than 0.25μrad rms and very stringent parameters for the VLS-polynomial. These grating structures have been measured by use of the Nano Optic Measuring Machine (NOM) at BESSY. Based on the principle of deflectometry the BESSY-NOM represents the latest generation of slope measuring metrology instruments. The NOM enables the inspection of optical components with a measurement uncertainty in the range of 0.05μrad rms. This is a five to tenfold improvement compared to state of the art metrology tools of today. Here it is demonstrated how these outstanding metrology capabilities have been applied for a sound characterisation of a challenging precision optical component with error limits five times below the specifications. In the shown example the grating's figure accuracy has been characterised by linescans and surface mapping measurements of the optical active sections. In additional measurements under Littrow condition the higher order diffraction signals of the laser pencil beam have been traced to measure the groove density variation of the different grating-structures with a lateral resolution of 1mm. In contrast to the sparse and point like measurements of the manufacturer, these high resolution measurements yield a "slope deviation equivalent" resulting from imperfections in the line density variation.

  17. Inspection of a Spherical Triple VLS-Grating for Self-Seeding of FLASH at DESY

    SciTech Connect

    Siewert, Frank; Lammert, Heiner; Reichardt, Gerd; Hahn, Ulrich; Treusch, Rolf; Reininger, Ruben

    2007-01-19

    To take benefit from the improved brilliance of the laser-like source, proposed beamlines at Free Electron Lasers (FEL) require optical elements of excellent precision, characterised by slope errors beyond the state of the art limit of 0.5{mu}rad rms for plane and spherical shape. Part of the monochromator beamline for self-seeding at the vacuum-ultraviolet Free Electron Laser (FLASH) at DESY is a triple Variable Line Spacing (VLS) grating of spherical shape. The three grating structures on a common substrate will cover the wavelength range from 6.4 to 60nm The challenging specifications of these grating structures are characterised by a slope error of less than 0.25{mu}rad rms and very stringent parameters for the VLS-polynomial. These grating structures have been measured by use of the Nano Optic Measuring Machine (NOM) at BESSY. Based on the principle of deflectometry the BESSY-NOM represents the latest generation of slope measuring metrology instruments. The NOM enables the inspection of optical components with a measurement uncertainty in the range of 0.05{mu}rad rms. This is a five to tenfold improvement compared to state of the art metrology tools of today. Here it is demonstrated how these outstanding metrology capabilities have been applied for a sound characterisation of a challenging precision optical component with error limits five times below the specifications. In the shown example the grating's figure accuracy has been characterised by linescans and surface mapping measurements of the optical active sections. In additional measurements under Littrow condition the higher order diffraction signals of the laser pencil beam have been traced to measure the groove density variation of the different grating-structures with a lateral resolution of 1mm. In contrast to the sparse and point like measurements of the manufacturer, these high resolution measurements yield a 'slope deviation equivalent' resulting from imperfections in the line density variation.

  18. NERSC Annual Report 2002

    SciTech Connect

    Hules, John

    2003-01-31

    The National Energy Research Scientific Computing Center (NERSC) is the primary computational resource for scientific research funded by the DOE Office of Science. The Annual Report for FY2002 includes a summary of recent computational science conducted on NERSC systems (with abstracts of significant and representative projects), and information about NERSC's current and planned systems and service

  19. NERSC Annual Report 2004

    SciTech Connect

    Hules, John; Bashor, Jon; Yarris, Lynn; McCullough, Julie; Preuss, Paul; Bethel, Wes

    2005-04-15

    The National Energy Research Scientific Computing Center (NERSC) is the premier computational resource for scientific research funded by the DOE Office of Science. The Annual Report includes summaries of recent significant and representative computational science projects conducted on NERSC systems as well as information about NERSC's current and planned systems and services.

  20. NRCC annual report, 1979

    SciTech Connect

    Not Available

    1980-11-01

    This annual report of the National Research for Computation in Chemistry (NRCC) Division describes the program of research workshops, software development, and scientific research of the Division in 1979. This year marked the first full calendar year of activity of the Division. Initial staffing in the core scientific areas was completed by the addition of a crystallographer.

  1. NERSC Annual Report 2005

    SciTech Connect

    Hules , John

    2006-07-31

    The National Energy Research Scientific Computing Center (NERSC) is the premier computational resource for scientific research funded by the DOE Office of Science. The Annual Report includes summaries of recent significant and representative computational science projects conducted on NERSC systems as well as information about NERSC's current and planned systems and services.

  2. Overview of the 80(th) Annual Scientific Meeting of the Japanese Circulation Society - The Past, Present and Future of Cardiovascular Medicine in Japan - - The 5(th) Anniversary of the Great East Japan Earthquake.

    PubMed

    Takahashi, Jun; Satoh, Kimio; Fukuda, Koji; Sugimura, Koichiro; Matsumoto, Yasuharu; Nakano, Makoto; Tsuburaya, Ryuji; Aoki, Tatsuo; Hao, Kiyotaka; Nishimiya, Kensuke; Ito, Kenta; Sakata, Yasuhiko; Shimokawa, Hiroaki

    2016-07-25

    The 80(th)Annual Scientific Meeting of the Japanese Circulation Society was held in Sendai, Japan, on March 18-20, 2016, which coincided with the 5(th)anniversary of the Great East Japan Earthquake that hit the Tohoku area on March 11, 2011. Thus, the main themes for this meeting were "The Past, Present and Future of Cardiovascular Medicine in Japan" and "The 5(th)Anniversary of the Great East Japan Earthquake". Despite the provincial location, approximately 15,000 people attended during the 3-day meeting, and there were in-depth discussions in each of the various sessions on these themes. Especially, to our great pleasure, the Japanese Royals, Emperor Akihito and Empress Michiko, kindly visited the panel exhibition of the Great East Japan Earthquake and spoke words of appreciation to us. The meeting successfully completed and we sincerely appreciate the great cooperation and support from all affiliates. (Circ J 2016; 80: 1689-1694). PMID:27385500

  3. Seasonal prevalence of gastrointestinal parasites in desi fowl (Gallus gallus domesticus) in and around Gannavaram, Andhra Pradesh.

    PubMed

    Sreedevi, C; Jyothisree, Ch; Rama Devi, V; Annapurna, P; Jeyabal, L

    2016-09-01

    A study was carried out to know the prevalence of gastrointestinal parasites in desi fowl in and nearby villages of Gannavaram, Andhra Pradesh for a period of 1 year. Screening of 492 samples comprising faecal samples and gastrointestinal tracts from freshly slaughtered desi birds at local poultry shops and samples from post mortem examinations at NTR College of Veterinary Science, Gannavaram revealed 63.21 % of gastrointestinal parasites. Faecal samples were examined by floatation technique using salt solution and samples positive for coccidian oocysts were sporulated in 2.5 % potassium dichromate solution for species identification. Adult worms were identified after routine processing and mounting. The species identified includes Davainea proglottina, Raillietina cesticillus and Raillietina echinobothrida in cestodes (32.47 %), Ascaridia galli, Capillaria annulata, Heterakis gallinarum in nematodes (39.87 %), Eimeria tenella, Eimeria acervulina and Eimeria necatrix in Eimeria spp. (39.87 %). Ascaridia galli and R. cesticillus and A. galli and Eimeria spp. were common in mixed infection (12.86 %). Ascaridia galli was the more prevalent species. No trematode parasite was identified during the study period. Significant (p = 0.001) relationship between the seasonality and prevalence of gastrointestinal parasites was observed (χ2 = 17.46, df = 2). Data revealed high prevalence in rainy season (43.41 %) followed by summer (38.91 %) and winter (17.68 %) seasons for all parasites except for A. galli and C. annulata infections which were higher in summer season. Results indicated high prevalence of gastrointestinal parasites in desi fowl in study area emphasizing the need of improved management practices of backyard poultry. PMID:27605762

  4. DESI-MS2: a rapid and innovative method for trace analysis of six cytostatic drugs in health care setting.

    PubMed

    Fabrizi, Giovanni; Fioretti, Marzia; Rocca, Lucia Mainero; Curini, Roberta

    2012-05-01

    With the aim of establishing exposure levels for hospital personnel preparing and administering cytostatic drugs (CDs), here, we present an innovative screening method based on the use of the desorption electrospray ionization (DESI) interface coupled with a hybrid quadrupole linear ion trap mass spectrometer. A rapid, simple, and sensitive procedure was developed for the simultaneous surface monitoring of cyclophosphamide, dacarbazine, methotrexate, vincristine, gemcitabine, and cytarabine. Since analytes were in the solid state, a novel approach based on the use of passive samplers was combined with the direct analysis of wipes. A PTFE-printed glass slide was used as a passive sampler, while hydrophobic centers of Swiffer® cloths were judged extremely efficient as wipe samplers. After the sampling period, the CD collectors were directly processed with the DESI-MS system without any further treatment. MS/MS confirmatory analysis was conducted using selected reaction monitoring in the positive ion mode and detection limits were evaluated. Values were at the picograms per square millimeter levels on the passive collector and at the picograms per square centimeter levels for the wipe ones. Direct determination on solid-state samples combined with mass spectrometry selectivity provided a powerful tool so far unapplied to occupational hygiene. PMID:22200922

  5. Scientific Misconduct.

    PubMed

    Gross, Charles

    2016-01-01

    Scientific misconduct has been defined as fabrication, falsification, and plagiarism. Scientific misconduct has occurred throughout the history of science. The US government began to take systematic interest in such misconduct in the 1980s. Since then, a number of studies have examined how frequently individual scientists have observed scientific misconduct or were involved in it. Although the studies vary considerably in their methodology and in the nature and size of their samples, in most studies at least 10% of the scientists sampled reported having observed scientific misconduct. In addition to studies of the incidence of scientific misconduct, this review considers the recent increase in paper retractions, the role of social media in scientific ethics, several instructional examples of egregious scientific misconduct, and potential methods to reduce research misconduct. PMID:26273897

  6. Desorption Electrospray Ionization (DESI) Mass Spectrometric Imaging of the Distribution of Rohitukine in the Seedling of Dysoxylum binectariferum Hook. F

    PubMed Central

    Mohana Kumara, Patel; Srimany, Amitava; Arunan, Suganya; Ravikanth, Gudasalamani; Uma Shaanker, Ramanan; Pradeep, Thalappil

    2016-01-01

    Ambient ionization mass spectrometric imaging of all parts of the seedling of Dysoxylum binectariferum Hook. f (Meliaceae) was performed to reconstruct the molecular distribution of rohitukine (Rh) and related compounds. The species accumulates Rh, a prominent chromone alkaloid, in its seeds, fruits, and stem bark. Rh possesses anti-inflammatory, anti-cancer, and immuno-modulatory properties. Desorption electrospray ionization mass spectrometry imaging (DESI MSI) and electrospray ionization (ESI) tandem mass spectrometry (MS/MS) analysis detected Rh as well as its glycosylated, acetylated, oxidized, and methoxylated analogues. Rh was predominantly distributed in the main roots, collar region of the stem, and young leaves. In the stem and roots, Rh was primarily restricted to the cortex region. The identities of the metabolites were assigned based on both the fragmentation patterns and exact mass analyses. We discuss these results, with specific reference to the possible pathways of Rh biosynthesis and translocation during seedling development in D. binectariferum. PMID:27362422

  7. Development and validation of a DESI-HRMS/MS method for the fast profiling of esomeprazole and its metabolites in rat plasma: a pharmacokinetic study.

    PubMed

    Rossi, Alessandra; Castrati, Luca; Colombo, Paolo; Flammini, Lisa; Barocelli, Elisabetta; Bettini, Ruggero; Elviri, Lisa

    2016-02-01

    The advances in pharmaceutical development and drug discovery impose the availability of reliable high-throughput screening methods for the rapid evaluation of drug metabolism and pharmacokinetic (PK) in biological samples. Here, a desorption electrospray mass spectrometry (DESI-MS) method has been developed and validated for the PK profiling of esomeprazole and its metabolites (5-hydroxyomeprazole and omeprazole sulfone) in rat plasma. Rats were treated with an esomeprazole solution (2.5 mg/mL) for endovenous administration and the analyte levels were profiled over 2 h after liquid-liquid extraction from plasma. MS and tandem mass spectrometry (MS/MS) experiments were performed by using a DESI-LTQ-Orbitrap XL instrument and an on-spot fixed time analysis on PMMA surfaces. Validation was performed for the esomeprazole. The DESI-MS/MS method exhibited for the esomepazole excellent sensitivity (limit of detection (LOD)=60 ng/mL), linearity (0.2-20 µg/mL concentration range; y=23848(±361)X, n=15; r(2) =0.987) and precision (RSD<9%) by using an internal standard method. The PK results were discussed in terms of Area Under the Curve, Cmax and Tmax . Data reliability was demonstrated by comparison with a liquid chromatography-tandem mass spectrometry method (p>0.05). The data achieved demonstrated that the DESI-MS method is suitable for sensitive and fast profiling of a drug and its metabolites at the therapeutic concentration levels. PMID:25922056

  8. Scientific Fraud.

    ERIC Educational Resources Information Center

    Goodstein, David

    1991-01-01

    A discussion of fraud in the presentation of results of scientific research cites cases looks at variations in the degree of misrepresentation, kinds and intents of fraud, attention given by public agencies (National Institutes of Health, National Science Foundation, Public Health Service), and differences between scientific and civil fraud. (MSE)

  9. NERSC 1998 annual report

    SciTech Connect

    Hules, John

    1999-03-01

    This 1998 annual report from the National Scientific Energy Research Computing Center (NERSC) presents the year in review of the following categories: Computational Science; Computer Science and Applied Mathematics; and Systems and Services. Also presented are science highlights in the following categories: Basic Energy Sciences; Biological and Environmental Research; Fusion Energy Sciences; High Energy and Nuclear Physics; and Advanced Scientific Computing Research and Other Projects.

  10. NERSC 2001 Annual Report

    SciTech Connect

    Hules, John

    2001-12-12

    The National Energy Research Scientific Computing Center (NERSC) is the primary computational resource for scientific research funded by the DOE Office of Science. The Annual Report for FY2001 includes a summary of recent computational science conducted on NERSC systems (with abstracts of significant and representative projects); information about NERSC's current systems and services; descriptions of Berkeley Lab's current research and development projects in applied mathematics, computer science, and computational science; and a brief summary of NERSC's Strategic Plan for 2002-2005.

  11. Trace detection of non-uniformly distributed analytes on surfaces using mass transfer and large-area desorption electrospray ionization (DESI) mass spectrometry.

    PubMed

    Soparawalla, Santosh; Salazar, Gary A; Sokol, Ewa; Perry, Richard H; Cooks, R Graham

    2010-08-01

    Ambient ionization methods such as desorption electrospray ionization (DESI) allow the analysis of chemicals adsorbed at surfaces without the need for sample (or surface) pretreatment. A limitation of current implementations of these ionization sources is the small size of the area that can be sampled. This makes examination of surfaces of large areas time-consuming because of the need to raster across the surface. This paper describes a DESI source that produces a spray plume with an effective desorption/ionization area of 3.6 cm(2), some 200 times larger than given by conventional DESI sources. Rhodamine 6G and several drugs of abuse (codeine, heroin and diazepam) were used to demonstrate the ability to use large-area DESI MS to perform rapid (a few seconds) representative sampling of areas of the order of several square centimetres without scanning the probe across the surface. The large area ion source displayed high sensitivity (limits of detection in the high nanogram range) and high reproducibility (approximately 20 to 35% relative standard deviation). The rapid analysis of even larger surfaces (hundreds of cm(2)) for traces of explosives is possible using a sorbent surface wipe followed by large-area DESI interrogation performed directly on the wipe material. The performance of this mass transfer dry wipe method was examined by determination of the limits of detection of several explosives. Surfaces with different topographies and compositions were also tested. Using this method, absolute limits of detection observed for HMX and RDX from plastic surfaces and skin were found to be as low as 10 ng cm(-2). The concentration of residue from large surface areas in this technique allowed the detection of 100 ng of explosives from surfaces with areas ranging from 1.00 x 10(3) cm(2) to 1.40 x 10(4) cm(2). PMID:20539884

  12. Scientific Globish versus scientific English.

    PubMed

    Tychinin, Dmitry N; Kamnev, Alexander A

    2013-10-01

    The proposed adoption of 'scientific Globish' as a simplified language standard for scholarly communication may appeal to authors who have difficulty with English proficiency. However, Globish might not justify the hopes being pinned on it and might open the door to further deterioration of the quality of English-language scientific writing. PMID:23928006

  13. Scientific Misconduct.

    ERIC Educational Resources Information Center

    Goodstein, David

    2002-01-01

    Explores scientific fraud, asserting that while few scientists actually falsify results, the field has become so competitive that many are misbehaving in other ways; an example would be unreasonable criticism by anonymous peer reviewers. (EV)

  14. Scientific millenarianism

    SciTech Connect

    Weinberg, A.M.

    1997-12-01

    Today, for the first time, scientific concerns are seriously being addressed that span future times--hundreds, even thousands, or more years in the future. One is witnessing what the author calls scientific millenarianism. Are such concerns for the distant future exercises in futility, or are they real issues that, to the everlasting gratitude of future generations, this generation has identified, warned about and even suggested how to cope with in the distant future? Can the four potential catastrophes--bolide impact, CO{sub 2} warming, radioactive wastes and thermonuclear war--be avoided by technical fixes, institutional responses, religion, or by doing nothing? These are the questions addressed in this paper.

  15. Search for resonance decays to a ν¯ plus jet in e+p scattering at DESY HERA

    NASA Astrophysics Data System (ADS)

    Breitweg, J.; Chekanov, S.; Derrick, M.; Krakauer, D.; Magill, S.; Musgrave, B.; Pellegrino, A.; Repond, J.; Stanek, R.; Yoshida, R.; Mattingly, M. C.; Antonioli, P.; Bari, G.; Basile, M.; Bellagamba, L.; Boscherini, D.; Bruni, A.; Bruni, G.; Romeo, G. Cara; Cifarelli, L.; Cindolo, F.; Contin, A.; Corradi, M.; de Pasquale, S.; Giusti, P.; Iacobucci, G.; Levi, G.; Margotti, A.; Massam, T.; Nania, R.; Palmonari, F.; Pesci, A.; Sartorelli, G.; Zichichi, A.; Amelung, C.; Bornheim, A.; Brock, I.; Coböken, K.; Crittenden, J.; Deffner, R.; Hartmann, H.; Heinloth, K.; Hilger, E.; Irrgang, P.; Jakob, H.-P.; Kappes, A.; Katz, U. F.; Kerger, R.; Paul, E.; Rautenberg, J.; Schnurbusch, H.; Stifutkin, A.; Tandler, J.; Voss, K. C.; Weber, A.; Wieber, H.; Bailey, D. S.; Barret, O.; Brook, N. H.; Foster, B.; Heath, G. P.; Heath, H. F.; Rodrigues, E.; Scott, J.; Tapper, R. J.; Capua, M.; Mastroberardino, A.; Schioppa, M.; Susinno, G.; Jeoung, H. Y.; Kim, J. Y.; Lee, J. H.; Lim, I. T.; Ma, K. J.; Pac, M. Y.; Caldwell, A.; Liu, W.; Liu, X.; Mellado, B.; Paganis, S.; Sampson, S.; Schmidke, W. B.; Sciulli, F.; Chwastowski, J.; Eskreys, A.; Figiel, J.; Klimek, K.; Olkiewicz, K.; Piotrzkowski, K.; Przybycień, M. B.; Stopa, P.; Zawiejski, L.; Bednarek, B.; Jeleń, K.; Kisielewska, D.; Kowal, A. M.; Kowalski, T.; Przybycień, M.; Rulikowska-Zarȩbska, E.; Suszycki, L.; Szuba, D.; Kotański, A.; Bauerdick, L. A.; Behrens, U.; Bienlein, J. K.; Borras, K.; Chiochia, V.; Dannheim, D.; Desler, K.; Drews, G.; Fox-Murphy, A.; Fricke, U.; Goebel, F.; Goers, S.; Göttlicher, P.; Graciani, R.; Haas, T.; Hain, W.; Hartner, G. F.; Hasell, D.; Hebbel, K.; Hillert, S.; Kasemann, M.; Koch, W.; Kötz, U.; Kowalski, H.; Labes, H.; Lindemann, L.; Löhr, B.; Mankel, R.; Martens, J.; Martínez, M.; Milite, M.; Moritz, M.; Notz, D.; Petrucci, M. C.; Polini, A.; Rohde, M.; Savin, A. A.; Schneekloth, U.; Selonke, F.; Sievers, M.; Stonjek, S.; Wolf, G.; Wollmer, U.; Youngman, C.; Zeuner, W.; Coldewey, C.; Lopez-Duran Viani, A.; Meyer, A.; Schlenstedt, S.; Straub, P. B.; Barbagli, G.; Gallo, E.; Parenti, A.; Pelfer, P. G.; Bamberger, A.; Benen, A.; Coppola, N.; Eisenhardt, S.; Markun, P.; Raach, H.; Wölfle, S.; Bussey, P. J.; Bell, M.; Doyle, A. T.; Glasman, C.; Lee, S. W.; Lupi, A.; MacDonald, N.; McCance, G. J.; Saxon, D. H.; Sinclair, L. E.; Skillicorn, I. O.; Waugh, R.; Bohnet, I.; Gendner, N.; Holm, U.; Meyer-Larsen, A.; Salehi, H.; Wick, K.; Carli, T.; Garfagnini, A.; Gialas, I.; Gladilin, L. K.; Kçira, D.; Klanner, R.; Lohrmann, E.; Gonçalo, R.; Long, K. R.; Miller, D. B.; Tapper, A. D.; Walker, R.; Mallik, U.; Cloth, P.; Filges, D.; Ishii, T.; Kuze, M.; Nagano, K.; Tokushuku, K.; Yamada, S.; Yamazaki, Y.; Ahn, S. H.; Lee, S. B.; Park, S. K.; Lim, H.; Park, I. H.; Son, D.; Barreiro, F.; García, G.; González, O.; Labarga, L.; del Peso, J.; Redondo, I.; Terrón, J.; Vázquez, M.; Barbi, M.; Corriveau, F.; Hanna, D. S.; Ochs, A.; Padhi, S.; Stairs, D. G.; Wing, M.; Tsurugai, T.; Antonov, A.; Bashkirov, V.; Danilov, M.; Dolgoshein, B. A.; Gladkov, D.; Sosnovtsev, V.; Suchkov, S.; Dementiev, R. K.; Ermolov, P. F.; Golubkov, Yu. A.; Katkov, I. I.; Khein, L. A.; Korotkova, N. A.; Korzhavina, I. A.; Kuzmin, V. A.; Lukina, O. Yu.; Proskuryakov, A. S.; Shcheglova, L. M.; Solomin, A. N.; Vlasov, N. N.; Zotkin, S. A.; Bokel, C.; Botje, M.; Brümmer, N.; Engelen, J.; Grijpink, S.; Koffeman, E.; Kooijman, P.; Schagen, S.; van Sighem, A.; Tassi, E.; Tiecke, H.; Tuning, N.; Velthuis, J. J.; Vossebeld, J.; Wiggers, L.; de Wolf, E.; Bylsma, B.; Durkin, L. S.; Gilmore, J.; Ginsburg, C. M.; Kim, C. L.; Ling, T. Y.; Boogert, S.; Cooper-Sarkar, A. M.; Devenish, R. C.; Große-Knetter, J.; Matsushita, T.; Ruske, O.; Sutton, M. R.; Walczak, R.; Bertolin, A.; Brugnera, R.; Carlin, R.; dal Corso, F.; Dosselli, U.; Dusini, S.; Limentani, S.; Morandin, M.; Posocco, M.; Stanco, L.; Stroili, R.; Turcato, M.; Voci, C.; Adamczyk, L.; Iannotti, L.; Oh, B. Y.; Okrasiński, J. R.; Saull, P. R.; Toothacker, W. S.; Whitmore, J. J.; Iga, Y.; D'agostini, G.; Marini, G.; Nigro, A.; Cormack, C.; Hart, J. C.; McCubbin, N. A.; Shah, T. P.; Epperson, D.; Heusch, C.; Sadrozinski, H. F.-W.; Seiden, A.; Wichmann, R.; Williams, D. C.; Pavel, N.; Abramowicz, H.; Dagan, S.; Kananov, S.; Kreisel, A.; Levy, A.; Abe, T.; Fusayasu, T.; Umemori, K.; Yamashita, T.; Hamatsu, R.; Hirose, T.; Inuzuka, M.; Kitamura, S.; Nishimura, T.; Arneodo, M.; Cartiglia, N.; Cirio, R.; Costa, M.; Ferrero, M. I.; Maselli, S.; Monaco, V.; Peroni, C.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Bailey, D. C.; Fagerstroem, C.-P.; Galea, R.; Koop, T.; Levman, G. M.; Martin, J. F.; Orr, R. S.; Polenz, S.; Sabetfakhri, A.; Simmons, D.; Butterworth, J. M.; Hayes, M. E.; Heaphy, E. A.; Jones, T. W.; Lane, J. B.; West, B. J.; Ciborowski, J.; Ciesielski, R.; Grzelak, G.; Nowak, R. J.; Pawlak, J. M.; Pawlak, R.; Smalska, B.; Tymieniecka, T.; Wróblewski, A. K.; Zakrzewski, J. A.; Żarnecki, A. F.; Adamus, M.; Gadaj, T.; Deppe, O.; Eisenberg, Y.; Hochman, D.; Karshon, U.; Badgett, W. F.; Chapin, D.; Cross, R.; Foudas, C.; Mattingly, S.; Reeder, D. D.; Smith, W. H.; Vaiciulis, A.; Wildschek, T.; Wodarczyk, M.; Deshpande, A.; Dhawan, S.; Hughes, V. W.; Bhadra, S.; Catterall, C.; Cole, J. E.; Frisken, W. R.; Hall-Wilton, R.; Khakzad, M.; Menary, S.

    2001-03-01

    A study of the ν¯-jet mass spectrum in e+p-->ν¯X events at a center-of-mass energy 300 GeV has been performed with the ZEUS detector at the HERA collider at DESY using an integrated luminosity of 47.7 pb-1. The mass spectrum is in good agreement with that expected from standard model processes over the ν¯-jet mass range studied. No significant excess attributable to the decay of a narrow resonance is observed. By using both e+p-->e+X and e+p-->ν¯X data, mass-dependent limits are set on the s-channel production of scalar and vector resonant states. Couplings to first-generation quarks are considered and limits are presented as a function of the e+q and ν¯q branching ratios. These limits are used to constrain the production of leptoquarks and R-parity violating squarks.

  16. Simulations of laser-wakefield acceleration with external electron-bunch injection for REGAE experiments at DESY

    SciTech Connect

    Grebenyuk, Julia; Mehrling, Timon; Tsung, Frank S.; Floettman, Klaus; Osterhoff, Jens

    2012-12-21

    We present particle-in-cell simulations for future laser-plasma wakefield experiments with external bunch injection at the REGAE accelerator facility at DESY, Hamburg, Germany. Two effects have been studied in detail: emittance evolution of electron bunches externally injected into a wake, and longitudinal bunch compression inside the wakefield. Results show significant transverse emittance growth during the injection process, if the electron bunch is not matched to its intrinsic betatron motion inside the wakefield. This might introduce the necessity to include beam-matching sections upstream of each plasma-accelerator section with fundamental implications on the design of staged laser wakefield accelerators. When externally injected at the zero-field crossing of the laser-driven wake, the electron bunch may undergo significant compression in longitudinal direction and be accelerated simultaneously due to the gradient in the acting force. The mechanism would allow for production of single high-energy, ultra-short (on the order of one femtosecond) bunches at REGAE. The optimal conditions for maximal bunch compression are discussed in the presented studies.

  17. Electrospun Nanofiber Mats as "Smart Surfaces" for Desorption Electrospray Ionization Mass Spectrometry (DESI MS)-Based Analysis and Imprint Imaging.

    PubMed

    Hemalatha, R G; Ganayee, Mohd Azhardin; Pradeep, T

    2016-06-01

    In this paper, desorption electrospray ionization mass spectrometry (DESI MS)-based molecular analysis and imprint imaging using electrospun nylon-6 nanofiber mats are demonstrated for various analytical contexts. Uniform mats of varying thicknesses composed of ∼200 nm diameter fibers were prepared using needleless electrospinning. Analytical applications requiring rapid understanding of the analytes in single drops, dyes, inks, and/or plant extracts incorporated directly into the nanofibers are discussed with illustrations. The possibility to imprint patterns made of printing inks, plant parts (such as petals, leaves, and slices of rhizomes), and fungal growth on fruits with their faithful reproductions on the nanofiber mats is illustrated with suitable examples. Metabolites were identified by tandem mass spectrometry data available in the literature and in databases. The results highlight the significance of electrospun nanofiber mats as smart surfaces to capture diverse classes of compounds for rapid detection or to imprint imaging under ambient conditions. Large surface area, appropriate chemical functionalities exposed, and easiness of desorption due to weaker interactions of the analyte species are the specific advantages of nanofibers for this application. PMID:27159150

  18. The Extreme Conditions Beamline at PETRA III, DESY: Possibilities to conduct time resolved monochromatic diffraction experiments in dynamic and laser heated DAC

    NASA Astrophysics Data System (ADS)

    Liermann, H.-P.; Morgenroth, W.; Ehnes, A.; Berghäuser, A.; Winkler, B.; Franz, H.; Weckert, E.

    2010-03-01

    We present plans for the new Extreme Conditions Beamline at PETRA III, DESY, Germany. The beamline is being designed and built with the specific goal to explore time resolved high-pressure and -temperature x-ray diffraction experiments in the dynamic and laser heated diamond anvil cell. Within we discuss the conceptual design of the optical components and experimental setup to conduct monochromatic high-pressure powder diffraction experiments in the sub-second time regime.

  19. Scientific Documentation.

    ERIC Educational Resources Information Center

    Pieper, Gail W.

    1980-01-01

    Describes how scientific documentation is taught in three 50-minute sessions in a technical writing course. Tells how session one distinguishes between in-text notes, footnotes, and reference entries; session two discusses the author-year system of citing references; and session three is concerned with the author-number system of reference…

  20. Scientific Inquiry

    ERIC Educational Resources Information Center

    National Science Teachers Association (NJ1), 2004

    2004-01-01

    Scientific inquiry reflects how scientists come to understand the natural world, and it is at the heart of how students learn. From a very early age, children interact with their environment, ask questions, and seek ways to answer those questions. Understanding science content is significantly enhanced when ideas are anchored to inquiry…

  1. [Scientific presentation].

    PubMed

    Kraft, Giuliano

    2002-01-01

    To give a correct and effective scientific presentation, is an arduous task that asks for close examination of basic techniques of communication. This article proposes indications and suggestions to help public speakers to be communicators, to use visual aids and it explains how to capture the audience attention. PMID:12599721

  2. Scientific Claims versus Scientific Knowledge.

    ERIC Educational Resources Information Center

    Ramsey, John

    1991-01-01

    Provides activities that help students to understand the importance of the scientific method. The activities include the science of fusion and cold fusion; a group activity that analyzes and interprets the events surrounding cold fusion; and an application research project concerning a current science issue. (ZWH)

  3. Scientific Misconduct

    NASA Astrophysics Data System (ADS)

    Moore, John W.

    2002-12-01

    These cases provide a good basis for discussions of scientific ethics, particularly with respect to the responsibilities of colleagues in collaborative projects. With increasing numbers of students working in cooperative or collaborative groups, there may be opportunities for more than just discussion—similar issues of responsibility apply to the members of such groups. Further, this is an area where, “no clear, widely accepted standards of behavior exist” (1). Thus there is an opportunity to point out to students that scientific ethics, like science itself, is incomplete and needs constant attention to issues that result from new paradigms such as collaborative research. Finally, each of us can resolve to pay more attention to the contributions we and our colleagues make to collaborative projects, applying to our own work no less critical an eye than we would cast on the work of those we don’t know at all.

  4. Tuning of 2.998 GHz S-band hybrid buncher for injector upgrade of LINAC II at DESY

    NASA Astrophysics Data System (ADS)

    Nie, Y. C.; Liebig, C.; Hüning, M.; Schmitz, M.

    2014-10-01

    The injector upgrade of LINAC II at DESY aims to improve its reliability and mitigate the radiological activation of components due to electron loss at relatively high energy of hundreds of MeV. Therefore, a 2.998 GHz hybrid buncher has been developed and will be installed in between an existing 2.998 GHz pre-buncher and LINAC II. It comprises a 1-cell standing-wave (SW) section for rapid electron acceleration and a 13-cells traveling-wave (TW) section for further beam bunching and acceleration. This paper focuses on its radio-frequency tuning procedure. The tuning strategy combines a non-resonant bead-pull measurement of complex electric field and a linear model for local reflection coefficient calculation. It is demonstrated that imaginary part of the local reflection coefficient represents the field distribution straightforwardly, based on which the structure can be tuned from cell to cell. During tuning, special attention has been paid to the field enhancement in the SW section to ensure its beam-capturing capability. Field amplitude and phase, global and local reflection coefficients have been analyzed for two different frequencies simultaneously, i.e. the intrinsic frequency of the structure and the target frequency, to avoid over-tuning. The tuning result is satisfying. For the target frequency, field unflatness of the TW section has been reduced from ±9% to ±4%, and field in the SW section has been enhanced significantly. Meanwhile, in the TW section, the deviation of phase advances between adjacent cells from the nominal value 120° has been reduced from the range ±5° to ±2°. By using ASTRA simulation, it has been verified that the residual detuning of the structure is acceptable in view of the beam dynamics performance.

  5. NSLS annual report 1984

    SciTech Connect

    Klaffky, R.; Thomlinson, W.

    1984-01-01

    The first comprehensive Annual Report of the National Synchrotron Light Source comes at a time of great activity and forward motion for the facility. In the following pages we outline the management changes that have taken place in the past year, the progress that has been made in the commissioning of the x-ray ring and in the enhanced utilization of the uv ring, together with an extensive discussion of the interesting scientific experiments that have been carried out.

  6. Linking Research to Policy, Practice, and Education: Lessons Learned, Tasks Ahead. Program Abstracts. Annual Scientific Meeting of the Gerontological Society of America (53rd, Washington, DC, November 17-21, 2000).

    ERIC Educational Resources Information Center

    Gerontologist, 2000

    2000-01-01

    This publication contains abstracts from the 53rd annual meeting of the Gerontological Society of America. The abstracts are arranged numerically by the session number in which they appear. Several abstracts are listed under each of the 388 sessions. Although the sessions are not limited to one topic, the dominant theme is education concerning all…

  7. Summer Events at the Scientific Library | Poster

    Cancer.gov

    Two exciting events are coming this summer from the Scientific Library—the annual Student Science Jeopardy Tournament and the Summer Video Series. This year, the 10th Annual Student Science Jeopardy Tournament will be held on Wednesday, July 20, beginning at 10 a.m. in the auditorium of Building 549. The event will also be streamed live to the Advanced Technology Research Facility (ATRF), room E1203.

  8. Free-electron laser at the TESLA Test Facility at DESY: toward a tunable short-pulsed soft x-ray source

    NASA Astrophysics Data System (ADS)

    Gerth, Christopher

    2001-12-01

    A high peak current, low emittance, short pulse electron beam can produce intense, laser-like radiation in a single pass through a long periodic magnetic structure. The construction of such free-electron lasers (FELs) based on self-amplified spontaneous emission (SASE) has become feasible by recent advances in accelerator technologies. Since SASE FELs do not require any optical components they are promising sources for the generation of intense, sub- picosecond laser pulses which are continuously tunable over a wide wavelength range in the vacuum ultraviolet (VUV) and X-ray region. In the first phase of the VUV-FEL (phase I) at the TESLA Test Facility at DESY, SASE was achieved for the first time in the VUV at wavelengths between 80 and 180 nm. The concept of the VUV FEL at DESY and first experimental results are presented. The second phase of the TESLA Test Facility (phase II), which includes an increase of the electron beam energy to 1 GeV, aims at the construction of a SASE FEL operating in the soft X-ray region. An overview of the current status and the activities toward a soft X-ray FEL user facility is given.

  9. PREDON Scientific Data Preservation 2014

    NASA Astrophysics Data System (ADS)

    Diaconu, C.; Kraml, S.; Surace, C.; Chateigner, D.; Libourel, T.; Laurent, A.; Lin, Y.; Schaming, M.; Benbernou, S.; Lebbah, M.; Boucon, D.; Cérin, C.; Azzag, H.; Mouron, P.; Nief, J.-Y.; Coutin, S.; Beckmann, V.

    Scientific data collected with modern sensors or dedicated detectors exceed very often the perimeter of the initial scientific design. These data are obtained more and more frequently with large material and human efforts. A large class of scientific experiments are in fact unique because of their large scale, with very small chances to be repeated and to superseded by new experiments in the same domain: for instance high energy physics and astrophysics experiments involve multi-annual developments and a simple duplication of efforts in order to reproduce old data is simply not affordable. Other scientific experiments are in fact unique by nature: earth science, medical sciences etc. since the collected data is "time-stamped" and thereby non-reproducible by new experiments or observations. In addition, scientific data collection increased dramatically in the recent years, participating to the so-called "data deluge" and inviting for common reflection in the context of "big data" investigations. The new knowledge obtained using these data should be preserved long term such that the access and the re-use are made possible and lead to an enhancement of the initial investment. Data observatories, based on open access policies and coupled with multi-disciplinary techniques for indexing and mining may lead to truly new paradigms in science. It is therefore of outmost importance to pursue a coherent and vigorous approach to preserve the scientific data at long term. The preservation remains nevertheless a challenge due to the complexity of the data structure, the fragility of the custom-made software environments as well as the lack of rigorous approaches in workflows and algorithms. To address this challenge, the PREDON project has been initiated in France in 2012 within the MASTODONS program: a Big Data scientific challenge, initiated and supported by the Interdisciplinary Mission of the National Centre for Scientific Research (CNRS). PREDON is a study group formed by

  10. Scientific Teaching Targeting Faculty from Diverse Institutions

    ERIC Educational Resources Information Center

    Gregg, Christopher S.; Ales, Jo Dale; Pomarico, Steven M.; Wischusen, E. William; Siebenaller, Joseph F.

    2013-01-01

    We offered four annual professional development workshops called STAR (for Scientific Teaching, Assessment, and Resources) modeled after the National Academies Summer Institute (SI) on Undergraduate Education in Biology. In contrast to the SI focus on training faculty from research universities, STAR's target was faculty from community…

  11. Scientific Word Processors Proliferate.

    ERIC Educational Resources Information Center

    Analytical Chemistry, 1985

    1985-01-01

    Briefly describes most of the currently available scientific word processing software packages. Unless noted, these products (including Molecular Presentation Graphics, ProofWriter, Spellbinder Scientific, Volkswriter Scientific, and WordMARC) run on the IBM PC family of microcomputers. (JN)

  12. Use of intermediate focus for grazing incidence small and wide angle x-ray scattering experiments at the beamline P03 of PETRA III, DESY

    SciTech Connect

    Santoro, G.; Buffet, A.; Döhrmann, R.; Yu, S.; Roth, S. V.; Körstgens, V.; Müller-Buschbaum, P.; Gedde, U.; Hedenqvist, M.

    2014-04-15

    We describe the new experimental possibilities of the micro- and nanofocus X-ray scattering beamline P03 of the synchrotron source PETRA III at DESY, Hamburg (Germany), which arise from experiments with smaller beam sizes in the micrometer range. This beamline has been upgraded recently to perform new kinds of experiments. The use of an intermediate focus allows for reducing the beam size of microfocused hard X-rays while preserving a large working distance between the focusing elements and the focus position. For the first time, this well-known methodology has been employed to grazing incidence small- and wide-angle X-ray scattering (GISAXS/GIWAXS). As examples, we highlight the applications to in situ studies using microfluidic devices in GISAXS geometry as well as the investigation of the crystallinity of thin films in GIWAXS geometry.

  13. Probing Molecular Associations of Secondary Organic Aerosol (SOA) Samples from CalNex 2010 with Nano-DESI High-Resolution Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    O'Brien, R. E.; Nguyen, T. B.; Laskin, A.; Laskin, J.; Hayes, P. L.; Liu, S.; Jimenez, J. L.; Russell, L. M.; Nizkorodov, S.; Goldstein, A. H.

    2012-12-01

    This project focuses on analyzing the identities of molecules that comprise oligomers in size resolved aerosol fractions. Since oligomers are generally too large and polar to be measured by typical GC/MS analysis, soft ionization with high resolution mass spectrometry is used to extend the range of observable compounds. Samples collected during CalNex 2010 in Bakersfield and Los Angeles and secondary organic aerosol (SOA) produced in a photochemical chamber by photooxidation of diesel (DSL) fuel and isoprene (ISO) under humid, high-NOx conditions have been analyzed with nanospray desorption electrospray ionization (nano-DESI) and a high-resolution Orbitrap mass spectrometer. The nano-DESI is a soft ionization technique that allows molecular ions to be observed and the Orbitrap has sufficient resolution to determine the elemental composition of almost all species above the detection limit. A large fraction of SOA is made up of high molecular weight oligomers which are thought to form through acid catalyzed reactions of photo-chemically processed volatile organic compounds (VOC). The formation of oligomers is influenced by the VOCs available, the amount of atmospheric sulfate and nitrate, and the magnitude of photo-chemical processing, among other potential influences. We present the elemental composition of chemical species in size resolved SOA samples with six-hour time resolution, providing the first time resolved data set for the study of these oligomers in atmospheric samples. We present a comparison of the degree of overlap between the ambient and chamber experiments as a novel method to examine sources for this fraction of SOA. Possible formation pathways and sources of observed compounds are analyzed by comparison to other concurrent measurements at the site.

  14. A report from the 60th Annual Scientific Session & Expo and I2 (Innovation and Intervention) Summit of the American College of Cardiology (April 2-5, 2011 - New Orleans, Louisiana, USA).

    PubMed

    Rabasseda, X

    2011-05-01

    As jazz and indeed most music has rhythm at its very core, so does life with the heart steadily pumping blood to the body. But as in jazz rhythm, irregular rhythm is paired with changes in pitch and velocity making melody and harmony, so it is to a large extent in heart disease, with irregular rhythm, irregular pumping effectiveness, arterial stiffness and so many diverse alterations completely changing the melody of life. Pairing music with the heart makes New Orleans a very reasonable place for the American College of Cardiology's scientific session to be held. To keep pace with the rhythm and the music, the following report will complement the meeting by briefly reviewing news reported during the oral and poster sessions that have a direct impact on treatments for cardiovascular diseases and risk factors. PMID:22013568

  15. Tick-borne encephalitis--a notifiable disease: report of the 15th Annual Meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE).

    PubMed

    Kunze, Ursula

    2013-09-01

    The 15th Meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE)--a group of neurologists, general practicioners, clinicians, travel physicans, virologists, pediatricians, and epidemiologists--was held under the title "Tick-Borne Encephalitis--a notifiable disease". With the inclusion of TBE in the list of notifiable diseases, an important measure was established to continue improving the level of evidence on TBE in Europe to better help guide policies and methods to lower the burden of this disease. Due to differences in diagnosis, case definition, and reporting in European countries, the overall epidemiology and burden of TBE remains unclear. During the meeting, important issues regarding epidemiology, risk areas, vaccination rates, and latest news on vaccination were presented and extensively discussed. A poster session provided an overview of the epidemiological situation 2012 in 13 European countries. PMID:23831368

  16. Tick-borne encephalitis-still on the map: Report of the 18th annual meeting of the international scientific working group on tick-borne encephalitis (ISW-TBE).

    PubMed

    Kunze, Ursula

    2016-07-01

    The 18th meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE)-a group of neurologists, general practitioners, clinicians, travel physicians, virologists, pediatricians and epidemiologists-was held under the title 'Tick-borne encephalitis-still on the map'. The conference agenda was divided into six sessions: 'National Implementation of EU notifiable disease status', 'Virology', 'Epidemiology and Risk areas & Poster Walk Epidemiological Update', 'Clinic', 'Environmental Factors' and 'New Findings and Diagnosis'. Key topics such as 'TBE as a notifiable disease-results of the third European survey', 'TBE vaccines over the years', 'Overview of flaviviruses', 'TBE virus phylogenetics', 'Current epidemiological developments and investigations', 'Clinical aspects', 'TBE in veterinary medicine', 'Laboratory diagnostic', 'Occupational risk', 'Allergy, obesity, and vaccination' were presented and extensively discussed. PMID:27189584

  17. Tick-borne encephalitis as a notifiable disease--Status quo and the way forward. Report of the 17th annual meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE).

    PubMed

    Kunze, Ursula

    2015-07-01

    The 17th meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE), a group of neurologists, general practicioners, clinicians, travel physicians, virologists, pediatricians, and epidemiologists, was held under the title "Tick-borne encephalitis as a notifiable disease--status quo and the way forward". The conference agenda was divided into three parts on the first day: "Epidemiology & Risk areas", "Poster Walk: Epidemiological Update in Europe", and "News in TBE Research". On the second day, a World Café Working Session took place where the participants could choose three tables out of six to join for discussion. Key topics on current epidemiological developments and investigations, risk areas, cases, travel and mobility, TBE in children, vaccination rates, and latest news on vaccination were presented and extensively discussed. PMID:26025269

  18. Plate tectonics: Scientific revolution or scientific program?

    NASA Astrophysics Data System (ADS)

    Mareschal, Jean-Claude

    In The Structure of Scientific Revolutions, Thomas S. Kuhn suggested that science progresses discontinuously: As a scientific theory becomes obsolete, a period of crisis results, at the end of which the old theory is overthrown and replaced by a new, sounder, more complete theory [Kuhn, 1962]. After the scientific community has accepted the new [paradigm,] it undertakes only routine research until a new crisis occurs, usually as a result of an anomalous experiment that accidentally happens to be critical.

  19. CMS Annual Report 2004

    SciTech Connect

    de la Rubia, T D; Shang, S P; Rennie, G; Fluss, M; Westbrook, C

    2005-07-29

    Glance at the articles in this report, and you will sense the transformation that is reshaping the landscape of materials science and chemistry. This transformation is bridging the gaps among chemistry, materials science, and biology--ushering in a wealth of innovative technologies with broad scientific impact. The emergence of this intersection is reinvigorating our strategic investment into areas that build on our strength of interdisciplinary science. It is at the intersection that we position our strategic vision into a future where we will provide radical materials innovations and solutions to our national-security programs and other sponsors. Our 2004 Annual Report describes how our successes and breakthroughs follow a path set forward by our strategic plan and four organizing research themes, each with key scientific accomplishments by our staff and collaborators. We have organized this report into two major sections: research themes and our dynamic teams. The research-theme sections focus on achievements arising from earlier investments while addressing future challenges. The dynamic teams section illustrates the directorate's organizational structure of divisions, centers, and institutes that support a team environment across disciplinary and institutional boundaries. The research presented in this annual report gives substantive examples of how we are proceeding in each of these four theme areas and how they are aligned with our national-security mission. By maintaining an organizational structure that offers an environment of collaborative problem-solving opportunities, we are able to nurture the discoveries and breakthroughs required for future successes.

  20. The soft x-ray free-electron laser FLASH at DESY: beamlines, diagnostics and end-stations

    NASA Astrophysics Data System (ADS)

    Tiedtke, K.; Azima, A.; von Bargen, N.; Bittner, L.; Bonfigt, S.; Düsterer, S.; Faatz, B.; Frühling, U.; Gensch, M.; Gerth, Ch; Guerassimova, N.; Hahn, U.; Hans, T.; Hesse, M.; Honkavaar, K.; Jastrow, U.; Juranic, P.; Kapitzki, S.; Keitel, B.; Kracht, T.; Kuhlmann, M.; Li, W. B.; Martins, M.; Núñez, T.; Plönjes, E.; Redlin, H.; Saldin, E. L.; Schneidmiller, E. A.; Schneider, J. R.; Schreiber, S.; Stojanovic, N.; Tavella, F.; Toleikis, S.; Treusch, R.; Weigelt, H.; Wellhöfer, M.; Wabnitz, H.; Yurkov, M. V.; Feldhaus, J.

    2009-02-01

    FLASH, the Free-electron LASer in Hamburg, is a worldwide unique source for extremely bright ultra-short laser-like pulses tunable in a wide spectral range in the extreme ultraviolet and soft x-ray region (Ackermann et al 2007 Nat. Photonics 1 336-42). To fully exploit the features of this new generation of light sources, a user facility with efficient radiation transport to the experimental area and novel online photon diagnostics capable of characterizing the unique parameters of the FLASH radiation has been built. It serves a broad user community active in many scientific fields ranging from atomic and molecular physics to plasma and solid state physics as well as chemistry and biology. A special focus is placed on the exploitation of the ultra-short FLASH pulses using pump-probe techniques. Thus, the facility is equipped with optical and THz sources synchronized to FLASH. This paper gives a detailed overview of the FLASH user facility.

  1. Tick-borne encephalitis (TBE): an underestimated risk…still: report of the 14th annual meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE).

    PubMed

    Kunze, Ursula

    2012-06-01

    Today, the risk of getting tick-borne encephalitis (TBE) is still underestimated in many parts of Europe and worldwide. Therefore, the 14th meeting of the International Scientific Working Group on Tick-Borne Encephalitis (ISW-TBE) - a group of neurologists, general practitioners, clinicians, travel physicians, virologists, pediatricians, and epidemiologists - was held under the title "Tick-borne encephalitis: an underestimated risk…still". Among the discussed issues were: TBE, an underestimated risk in children, a case report in two Dutch travelers, the very emotional report of a tick victim, an overview of the epidemiological situation, investigations to detect new TBE cases in Italy, TBE virus (TBEV) strains circulation in Northern Europe, TBE Program of the European Centre for Disease Prevention and Control (ECDC), efforts to increase the TBE vaccination rate in the Czech Republic, positioning statement of the World Health Organization (WHO), and TBE in dogs. To answer the question raised above: Yes, the risk of getting TBE is underestimated in children and adults, because awareness is still too low. It is still underestimated in several areas of Europe, where, for a lack of human cases, TBEV is thought to be absent. It is underestimated in travelers, because they still do not know enough about the risk, and diagnostic awareness in non-endemic countries is still low. PMID:22765977

  2. WWW: The Scientific Method

    ERIC Educational Resources Information Center

    Blystone, Robert V.; Blodgett, Kevin

    2006-01-01

    The scientific method is the principal methodology by which biological knowledge is gained and disseminated. As fundamental as the scientific method may be, its historical development is poorly understood, its definition is variable, and its deployment is uneven. Scientific progress may occur without the strictures imposed by the formal…

  3. 3 CFR - Scientific Integrity

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Scientific Integrity Presidential Documents Other Presidential Documents Memorandum of March 9, 2009 Scientific Integrity Memorandum for the Heads of Executive Departments and Agencies Science and the scientific process must inform and guide decisions of my Administration on a wide range of...

  4. Scientific Literacy: Whose Responsibility?

    ERIC Educational Resources Information Center

    Evans, Thomas P.

    1970-01-01

    Identifies various components of scientific literacy and characteristics of scientifically literate people. Discusses factors inhibiting scientific literacy. Suggested remedies: federal support for special programs, redesign of teacher education programs and science content courses at all levels, and setting up means of interpreting science to the…

  5. Redefining the "Scientific Method".

    ERIC Educational Resources Information Center

    Spiece, Kelly R.; Colosi, Joseph

    2000-01-01

    Surveys 15 introductory biology textbooks for their presentation of the scientific method. Teaching the scientific method involves more than simplified steps and subjectivity--human politics, cultural influences, and chance are all a part of science. Presents an activity for students to experience the scientific method. (Contains 34 references.)…

  6. High Throughput Screening of High-Affinity Ligands for Proteins with Anion-Binding Sites using Desorption Electrospray Ionization (DESI) Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Lu, Xin; Ning, Baoming; He, Dacheng; Huang, Lingyun; Yue, Xiangjun; Zhang, Qiming; Huang, Haiwei; Liu, Yang; He, Lan; Ouyang, Jin

    2014-03-01

    A high throughput screening system involving a linear ion trap (LTQ) analyzer, a house-made platform and a desorption electrospray ionization (DESI) source was established to screen ligands with a high affinity for proteins with anion-binding sites. The complexes were analyzed after incubation, ultrafiltration, washing, and displacement. A new anionic region inhibited dissociation (ARID) mechanism that was suitable for a protein with anion-binding site was proposed. We utilized the differences in detectable dissociation of protein-ligand complexes, combined with displacement experiments, to distinguish free ligands displaced from anion-binding sites from liberated ligands dissociated from nonspecific interactions. The method was validated by α1-acid glycoprotein (AGP) and (R), (S)-amlodipine. Site-specific enantioselectivity shown in our experiments was consistent with earlier studies. Obtaining all of the qualitative information of 15*3 samples in 2.3 min indicates that the analysis process is no longer the time-limiting step in the initial stage of drug discovery. Quantitative information verified that our method was at least a semiquantitative method.

  7. Probing Molecular Associations of Field-Collected and Laboratory-Generated SOA with Nano-DESI High-Resolution Mass Spectrometry

    SciTech Connect

    O'Brien, Rachel E.; Nguyen, Tran B.; Laskin, Alexander; Laskin, Julia; Hayes, Patrick L.; Liu, Shang; Jimenez, Jose L.; Russell, Lynn M.; Nizkorodov, Sergey; Goldstein, Allen H.

    2013-01-30

    Aerosol samples from the 2010 CalNex field study in Bakersfield (BF) and Los Angeles (LA) were analyzed using positive mode nanospray-desorption electrospray ionization mass spectrometry (nano-DESI-MS). Secondary organic aerosol (SOA) produced in a photochemical chamber by photooxidation of diesel (DSL) fuel and isoprene (ISO) under humid, high-NOx conditions, was analyzed for comparison. Three groups of organic compounds with zero, one, or two nitrogen atoms in their molecular formulas (0N, 1N, 2N) were compared in detail. The composition of ambient SOA exhibited greater overlap with DSL than with ISO. The overlap of the chamber experiments with the BF data was relatively consistent throughout the day while the overlap with LA data increased significantly in the noon-6pm sample, consistent with the SOA plume arriving from downtown Los Angeles. BF samples were more oxidized, contained more organic nitrogen, and had more overlap with the chamber data compared to LA samples. The addition of gaseous ammonia (NH3) to the DSL experiment was necessary to generate many of the 2N compounds observed in BF. This analysis demonstrates that DSL and ISO were important sources but cannot account for all of the observed ambient compounds indicating that other sources of organics were also likely important.

  8. Scientific dishonesty and good scientific practice.

    PubMed

    Andersen, D; Axelsen, N H; Riis, P

    1993-04-01

    Scientific dishonesty has been the subject of much public interest in recent years. Although the problem has had a low profile in Denmark, there is no reason to believe that it is non-existent. Several preconditions known to be important prevail here as well as in other countries, such as pressure to publish and severe competition for research grants and senior academic positions. The Danish Medical Research Council (DMRC) decided to respond to this problem by preparing a report on scientific dishonesty with suggestions to the research institutions on rules for good scientific practice and procedures for investigation of suspected dishonesty. To this end, an investigatory system was suggested. The system should consist of two regional committees and one national committee. They should be headed by high court judges and experienced health sciences researchers as members. The committees will investigate cases reported to them and conclude on whether dishonesty has been established and on whether the scientific work should be retracted. Sanctions shall remain the task of the institutions. Preventive measures comprise open access to and a long storage period for scientific data. PMID:8495601

  9. Scientific integrity memorandum

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2009-03-01

    U.S. President Barack Obama signed a presidential memorandum on 9 March to help restore scientific integrity in government decision making. The memorandum directs the White House Office of Science and Technology Policy to develop a strategy within 120 days that ensures that "the selection of scientists and technology professionals for science and technology positions in the executive branch is based on those individuals' scientific and technological knowledge, credentials, and experience; agencies make available to the public the scientific or technological findings or conclusions considered or relied upon in policy decisions; agencies use scientific and technological information that has been subject to well-established scientific processes such as peer review; and agencies have appropriate rules and procedures to ensure the integrity of the scientific process within the agency, including whistleblower protection."

  10. The Digital Road to Scientific Knowledge Diffusion; A Faster, Better Way to Scientific Progress?

    SciTech Connect

    Wojick, D E; Warnick, W L; Carroll, B C; Crowe, J

    2006-06-01

    With the United States federal government spending billions annually for research and development, ways to increase the productivity of that research can have a significant return on investment. The process by which science knowledge is spread is called diffusion. It is therefore important to better understand and measure the benefits of this diffusion of knowledge. In particular, it is important to understand whether advances in Internet searching can speed up the diffusion of scientific knowledge and accelerate scientific progress despite the fact that the vast majority of scientific information resources continue to be held in deep web databases that many search engines cannot fully access. To address the complexity of the search issue, the term global discovery is used for the act of searching across heterogeneous environments and distant communities. This article discusses these issues and describes research being conducted by the Office of Scientific and Technical Information (OSTI).

  11. Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY)

    PubMed Central

    Blanchet, Clement E.; Spilotros, Alessandro; Schwemmer, Frank; Graewert, Melissa A.; Kikhney, Alexey; Jeffries, Cy M.; Franke, Daniel; Mark, Daniel; Zengerle, Roland; Cipriani, Florent; Fiedler, Stefan; Roessle, Manfred; Svergun, Dmitri I.

    2015-01-01

    A high-brilliance synchrotron P12 beamline of the EMBL located at the PETRA III storage ring (DESY, Hamburg) is dedicated to biological small-angle X-ray scattering (SAXS) and has been designed and optimized for scattering experiments on macromolecular solutions. Scatterless slits reduce the parasitic scattering, a custom-designed miniature active beamstop ensures accurate data normalization and the photon-counting PILATUS 2M detector enables the background-free detection of weak scattering signals. The high flux and small beam size allow for rapid experiments with exposure time down to 30–50 ms covering the resolution range from about 300 to 0.5 nm. P12 possesses a versatile and flexible sample environment system that caters for the diverse experimental needs required to study macromolecular solutions. These include an in-vacuum capillary mode for standard batch sample analyses with robotic sample delivery and for continuous-flow in-line sample purification and characterization, as well as an in-air capillary time-resolved stopped-flow setup. A novel microfluidic centrifugal mixing device (SAXS disc) is developed for a high-throughput screening mode using sub-microlitre sample volumes. Automation is a key feature of P12; it is controlled by a beamline meta server, which coordinates and schedules experiments from either standard or nonstandard operational setups. The integrated SASFLOW pipeline automatically checks for consistency, and processes and analyses the data, providing near real-time assessments of overall parameters and the generation of low-resolution models within minutes of data collection. These advances, combined with a remote access option, allow for rapid high-throughput analysis, as well as time-resolved and screening experiments for novice and expert biological SAXS users. PMID:25844078

  12. 5 CFR 534.504 - Annual adjustment in pay.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Annual adjustment in pay. 534.504 Section 534.504 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY UNDER OTHER SYSTEMS Pay for Senior-Level and Scientific and Professional Positions § 534.504 Annual...

  13. 5 CFR 534.504 - Annual adjustment in pay.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Annual adjustment in pay. 534.504 Section 534.504 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY UNDER OTHER SYSTEMS Pay for Senior-Level and Scientific and Professional Positions § 534.504 Annual...

  14. 5 CFR 534.504 - Annual adjustment in pay.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Annual adjustment in pay. 534.504 Section 534.504 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY UNDER OTHER SYSTEMS Pay for Senior-Level and Scientific and Professional Positions § 534.504 Annual adjustment in pay. Effective at the beginning of...

  15. 5 CFR 534.504 - Annual adjustment in pay.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Annual adjustment in pay. 534.504 Section 534.504 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY UNDER OTHER SYSTEMS Pay for Senior-Level and Scientific and Professional Positions § 534.504 Annual...

  16. Scientific Ability and Creativity

    ERIC Educational Resources Information Center

    Heller, Kurt A.

    2007-01-01

    Following an introductory definition of "scientific ability and creativity", product-oriented, personality and social psychological approaches to studying scientific ability are examined with reference to competence and performance. Studies in the psychometric versus cognitive psychological paradigms are dealt with in more detail. These two…

  17. Scientific rigor through videogames.

    PubMed

    Treuille, Adrien; Das, Rhiju

    2014-11-01

    Hypothesis-driven experimentation - the scientific method - can be subverted by fraud, irreproducibility, and lack of rigorous predictive tests. A robust solution to these problems may be the 'massive open laboratory' model, recently embodied in the internet-scale videogame EteRNA. Deploying similar platforms throughout biology could enforce the scientific method more broadly. PMID:25300714

  18. Age and Scientific Performance.

    ERIC Educational Resources Information Center

    Cole, Stephen

    1979-01-01

    The long-standing belief that age is negatively associated with scientific productivity and creativity is shown to be based upon incorrect analysis of data. Studies reported in this article suggest that the relationship between age and scientific performance is influenced by the operation of the reward system. (Author)

  19. ATR National Scientific User Facility 2009 Annual Report

    SciTech Connect

    Todd R. Allen; Mitchell K. Meyer; Frances Marshall; Mary Catherine Thelen; Jeff Benson

    2010-11-01

    This report describes activities of the ATR NSUF from FY-2008 through FY-2009 and includes information on partner facilities, calls for proposals, users week and education programs. The report also contains project information on university research projects that were awarded by ATR NSUF in the fiscal years 2008 & 2009. This research is university-proposed researcher under a user facility agreement. All intellectual property from these experiments belongs to the university per the user agreement.

  20. Russia's scientific legacy

    NASA Astrophysics Data System (ADS)

    2015-01-01

    Many insights of Russian scientists are unknown or long-forgotten outside of Russia. Making the Russian literature accessible to the international scientific community could stimulate new lines of research.

  1. Report: Scientific Software.

    ERIC Educational Resources Information Center

    Borman, Stuart A.

    1985-01-01

    Discusses various aspects of scientific software, including evaluation and selection of commercial software products; program exchanges, catalogs, and other information sources; major data analysis packages; statistics and chemometrics software; and artificial intelligence. (JN)

  2. STARPROBE: Scientific rationale

    NASA Technical Reports Server (NTRS)

    Underwood, J. H. (Editor); Randolph, J. E. (Editor)

    1982-01-01

    The scientific rationale and instrumentation problems in the areas of solar internal dynamics and relativity, solar plasma and particle dynamics, and solar atmosphere structure were studied. Current STARPROBE mission and system design concepts are summarized.

  3. Scientific data requirements

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Each Scientific Data Requirement (SDR) is summarized in terms of professional discipline, research program, technical description, related parameters, geographical extent, resolution, error tolerance,space-based sensors systems, personnel, implementation expert, notes, and references.

  4. Anatomy of Scientific Evolution

    PubMed Central

    Yun, Jinhyuk; Kim, Pan-Jun; Jeong, Hawoong

    2015-01-01

    The quest for historically impactful science and technology provides invaluable insight into the innovation dynamics of human society, yet many studies are limited to qualitative and small-scale approaches. Here, we investigate scientific evolution through systematic analysis of a massive corpus of digitized English texts between 1800 and 2008. Our analysis reveals great predictability for long-prevailing scientific concepts based on the levels of their prior usage. Interestingly, once a threshold of early adoption rates is passed even slightly, scientific concepts can exhibit sudden leaps in their eventual lifetimes. We developed a mechanistic model to account for such results, indicating that slowly-but-commonly adopted science and technology surprisingly tend to have higher innate strength than fast-and-commonly adopted ones. The model prediction for disciplines other than science was also well verified. Our approach sheds light on unbiased and quantitative analysis of scientific evolution in society, and may provide a useful basis for policy-making. PMID:25671617

  5. Final Scientific Report (FSR)

    SciTech Connect

    Granzin, Bill

    2010-11-29

    The Flambeau River Papers Manufacturing Conversion for Energy Efficiency Project has identified the following goals and objectives: 1. A low pressure accumulator tank will be installed to capture low pressure gases for reuse. The estimated cost is $2.1 million with an energy savings of $500,000 annually or enough natural gas savings to heat 590 average Wisconsin homes. 2. Replace the steam turbine and upgrade Paper Machine #3, the largest of Flambeau River Papers machines, at a cost of $6.265 million. The result will save enough natural gas to heat 141 average homes, or about $1.2-million each year. 3. Install a new cyclonic and cell fracturing technology dryer to reduce moisture in both sludge and biomass wastes. The estimated cost of this task is $1.5-million with an annual energy savings of $700,000. It will also eliminate all coal burning at Flambeau River Papers (7,200 tons of coal annually).

  6. Scientific Data Management Center Scientific Data Integration

    SciTech Connect

    Critchlow, T J; Liu, L; Pu, C; Gupta, A; Ludaescher, B; Altintas, I; Vouk, M; Bitzer, D; Singh, M; Rosnick, D

    2003-01-31

    The Internet is becoming the preferred method for disseminating scientific data from a variety of disciplines. This has resulted in information overload on the part of the scientists, who are unable to query all of the relevant sources, even if they knew where to find them, what they contained, how to interact with them, and how to interpret the results. Thus instead of benefiting from this information rich environment, scientists become experts on a small number of sources and use those sources almost exclusively. Enabling information based scientific advances, in domains such as functional genomics, requires fully utilizing all available information. We are developing an end-to-end solution using leading-edge automatic wrapper generation, mediated query, and agent technology that will allow scientists to interact with more information sources than currently possible. Furthermore, by taking a workflow-based approach to this problem, we allow them to easily adjust the dataflow between the various sources to address their specific research needs.

  7. The Scientific Mentor

    ERIC Educational Resources Information Center

    Rodia, Becky

    2004-01-01

    This article describes the Cornell Science Challenge, an annual science fair held at Olin Hall at Weill Medical College of Cornell University. This science fair features seventh graders from East Middle School in New York who have been mentored for three months by actual scientists (graduate students, faculty members, laboratory technicians, and…

  8. Scientific/Techical Report

    SciTech Connect

    Dr. Chris Leighton, Neutron Scattering Society of American; Mr. J. Ardie Dillen, MRS Director of Finance and Administration

    2012-11-07

    The ACNS provides a focal point for the North American neutron user community, strengthening ties within this diverse group, and promoting neutron research in related disciplines. The conference thus serves a dual role as both a national user meeting and a scientific meeting. As a venue for scientific exchange, the ACNS showcases recent results and provides a forum for scientific discussion of neutron-enabled research in fields as diverse as hard and soft condensed matter, liquids, biology, magnetism, engineering materials, chemical spectroscopy, crystal structure, elementary excitations, fundamental physics, and development of neutron instrumentation. This is achieved through a combination of invited oral presentations, contributed oral presentations, and poster sessions. Adequate opportunity for spontaneous discussion and collaboration is also built into the ACNS program in order to foster free exchange of new scientific ideas and the potential for use of powerful neutron scattering methods beyond the current realms of application. The sixth American Conference on Neutron Scattering (ACNS 2012) provided essential information on the breadth and depth of current neutron-related research worldwide. A strong program of plenary, invited and contributed talks showcased recent scientific results in neutron science in a wide range of fields, including soft and hard condensed matter, biology, chemistry, energy and engineering applications, and neutron physics.

  9. Scientific ballooning in Japan

    NASA Astrophysics Data System (ADS)

    Makino, Fumiyoshi

    Activities in scientific ballooning in Japan during 1998-1999 are reported. The total number of scientific balloons flown in Japan in 1998 and 1999 was sixteen, eight flights in each year. The scientific objectives were observations of high energy cosmic electrons, air samplings at various altitudes, monitoring of atmospheric ozone density, Galactic infrared observations, and test flights of new type balloons. Balloon expeditions were conducted in Antarctica by the National Institute of Polar Research, in Russia, in Canada and in India in collaboration with foreign countries' institutes to investigate cosmic rays, Galactic infrared radiation, and Earth's atmosphere. There were three flights in Antarctica, four flights in Russia, three flights in Canada and two flights in India. Four test balloons were flown for balloon technology, which included pumpkin-type super-pressure balloon and a balloon made with ultra-thin polyethylene film of 3.4 μm thickness.

  10. The future scientific CCD

    NASA Technical Reports Server (NTRS)

    Janesick, J. R.; Elliott, T.; Collins, S.; Marsh, H.; Blouke, M. M.

    1984-01-01

    Since the first introduction of charge-coupled devices (CCDs) in 1970, CCDs have been considered for applications related to memories, logic circuits, and the detection of visible radiation. It is pointed out, however, that the mass market orientation of CCD development has left largely untapped the enormous potential of these devices for advanced scientific instrumentation. The present paper has, therefore, the objective to introduce the CCD characteristics to the scientific community, taking into account prospects for further improvement. Attention is given to evaluation criteria, a summary of current CCDs, CCD performance characteristics, absolute calibration tools, quantum efficiency, aspects of charge collection, charge transfer efficiency, read noise, and predictions regarding the characteristics of the next generation of silicon scientific CCD imagers.

  11. PLAGIARISM IN SCIENTIFIC PUBLISHING

    PubMed Central

    Masic, Izet

    2012-01-01

    Scientific publishing is the ultimate product of scientist work. Number of publications and their quoting are measures of scientist success while unpublished researches are invisible to the scientific community, and as such nonexistent. Researchers in their work rely on their predecessors, while the extent of use of one scientist work, as a source for the work of other authors is the verification of its contributions to the growth of human knowledge. If the author has published an article in a scientific journal it cannot publish the article in any other journal h with a few minor adjustments or without quoting parts of the first article, which are used in another article. Copyright infringement occurs when the author of a new article with or without the mentioning the author used substantial portions of previously published articles, including tables and figures. Scientific institutions and universities should,in accordance with the principles of Good Scientific Practice (GSP) and Good Laboratory Practices (GLP) have a center for monitoring,security, promotion and development of quality research. Establish rules and compliance to rules of good scientific practice are the obligations of each research institutions,universities and every individual-researchers,regardless of which area of science is investigated. In this way, internal quality control ensures that a research institution such as a university, assume responsibility for creating an environment that promotes standards of excellence, intellectual honesty and legality. Although the truth should be the aim of scientific research, it is not guiding fact for all scientists. The best way to reach the truth in its study and to avoid the methodological and ethical mistakes is to consistently apply scientific methods and ethical standards in research. Although variously defined plagiarism is basically intended to deceive the reader’s own scientific contribution. There is no general regulation of control of

  12. Plagiarism in scientific publishing.

    PubMed

    Masic, Izet

    2012-12-01

    Scientific publishing is the ultimate product of scientist work. Number of publications and their quoting are measures of scientist success while unpublished researches are invisible to the scientific community, and as such nonexistent. Researchers in their work rely on their predecessors, while the extent of use of one scientist work, as a source for the work of other authors is the verification of its contributions to the growth of human knowledge. If the author has published an article in a scientific journal it cannot publish the article in any other journal h with a few minor adjustments or without quoting parts of the first article, which are used in another article. Copyright infringement occurs when the author of a new article with or without the mentioning the author used substantial portions of previously published articles, including tables and figures. Scientific institutions and universities should,in accordance with the principles of Good Scientific Practice (GSP) and Good Laboratory Practices (GLP) have a center for monitoring,security, promotion and development of quality research. Establish rules and compliance to rules of good scientific practice are the obligations of each research institutions,universities and every individual-researchers,regardless of which area of science is investigated. In this way, internal quality control ensures that a research institution such as a university, assume responsibility for creating an environment that promotes standards of excellence, intellectual honesty and legality. Although the truth should be the aim of scientific research, it is not guiding fact for all scientists. The best way to reach the truth in its study and to avoid the methodological and ethical mistakes is to consistently apply scientific methods and ethical standards in research. Although variously defined plagiarism is basically intended to deceive the reader's own scientific contribution. There is no general regulation of control of

  13. NASA's Scientific Visualization Studio

    NASA Technical Reports Server (NTRS)

    Mitchell, Horace G.

    2003-01-01

    Since 1988, the Scientific Visualization Studio(SVS) at NASA Goddard Space Flight Center has produced scientific visualizations of NASA s scientific research and remote sensing data for public outreach. These visualizations take the form of images, animations, and end-to-end systems and have been used in many venues: from the network news to science programs such as NOVA, from museum exhibits at the Smithsonian to White House briefings. This presentation will give an overview of the major activities and accomplishments of the SVS, and some of the most interesting projects and systems developed at the SVS will be described. Particular emphasis will be given to the practices and procedures by which the SVS creates visualizations, from the hardware and software used to the structures and collaborations by which products are designed, developed, and delivered to customers. The web-based archival and delivery system for SVS visualizations at svs.gsfc.nasa.gov will also be described.

  14. Etiquette in scientific publishing.

    PubMed

    Krishnan, Vinod

    2013-10-01

    Publishing a scientific article in a journal with a high impact factor and a good reputation is considered prestigious among one's peer group and an essential achievement for career progression. In the drive to get their work published, researchers can forget, either intentionally or unintentionally, the ethics that should be followed in scientific publishing. In an environment where "publish or perish" rules the day, some authors might be tempted to bend or break rules. This special article is intended to raise awareness among orthodontic journal editors, authors, and readers about the types of scientific misconduct in the current publishing scenario and to provide insight into the ways these misconducts are managed by the Committee of Publishing Ethics. Case studies are presented, and various plagiarism detection software programs used by publishing companies are briefly described. PMID:24075666

  15. Making better scientific figures

    NASA Astrophysics Data System (ADS)

    Hawkins, Ed; McNeall, Doug

    2016-04-01

    In the words of the UK government chief scientific adviser "Science is not finished until it's communicated" (Walport 2013). The tools to produce good visual communication have never been so easily accessible to scientists as at the present. Correspondingly, it has never been easier to produce and disseminate poor graphics. In this presentation, we highlight some good practice and offer some practical advice in preparing scientific figures for presentation to peers or to the public. We identify common mistakes in visualisation, including some made by the authors, and offer some good reasons not to trust defaults in graphics software. In particular, we discuss the use of colour scales and share our experiences in running a social media campaign (http://tiny.cc/endrainbow) to replace the "rainbow" (also "jet", or "spectral") colour scale as the default in (climate) scientific visualisation.

  16. Recording Scientific Knowledge

    SciTech Connect

    Bowker, Geof

    2006-01-09

    The way we record knowledge, and the web of technical, formal, and social practices that surrounds it, inevitably affects the knowledge that we record. The ways we hold knowledge about the past - in handwritten manuscripts, in printed books, in file folders, in databases - shape the kind of stories we tell about that past. In this talk, I look at how over the past two hundred years, information technology has affected the nature and production of scientific knowledge. Further, I explore ways in which the emergent new cyberinfrastructure is changing our relationship to scientific practice.

  17. FY 2014 LDRD Annual Report Project Summaries

    SciTech Connect

    Tomchak, Dena

    2015-02-01

    The FY 2014 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support future DOE missions and national research priorities. LDRD is essential to INL - it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enahnces technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

  18. Environmental Molecular Sciences Laboratory 2004 Annual Report

    SciTech Connect

    White, Julia C.

    2005-04-17

    This 2004 Annual Report describes the research and accomplishments of staff and users of the W.R. Wiley Environmental Molecular Sciences Laboratory (EMSL), located in Richland, Washington. EMSL is a multidisciplinary, national scientific user facility and research organization, operated by Pacific Northwest National Laboratory (PNNL) for the U.S. Department of Energy's Office of Biological and Environmental Research. The resources and opportunities within the facility are an outgrowth of the U.S. Department of Energy's (DOE) commitment to fundamental research for understanding and resolving environmental and other critical scientific issues.

  19. Assessing Scientific Inquiry

    ERIC Educational Resources Information Center

    Peters, Erin

    2008-01-01

    Assessing student-led, open-ended scientific inquiry holds a unique problem for classroom teachers because of the diverse skills and content that emerge from student work. This article provides tangible strategies for teachers to assess divergent student-generated inquiry in a manner that is manageable for teachers, informative for students, and…

  20. Projecting the Scientific Method.

    ERIC Educational Resources Information Center

    Uthe, R. E.

    2000-01-01

    Describes how the gas laws are an excellent vehicle for introducing the steps of the scientific method. Students can use balloons and a simple apparatus to observe changes in various gas parameters, develop ideas about the changes they see, collect numerical data, test their ideas, derive simple equations for the relationships, and use the…

  1. Scientific Component Technology Initiative

    SciTech Connect

    Kohn, S; Bosl, B; Dahlgren, T; Kumfert, G; Smith, S

    2003-02-07

    The laboratory has invested a significant amount of resources towards the development of high-performance scientific simulation software, including numerical libraries, visualization, steering, software frameworks, and physics packages. Unfortunately, because this software was not designed for interoperability and re-use, it is often difficult to share these sophisticated software packages among applications due to differences in implementation language, programming style, or calling interfaces. This LDRD Strategic Initiative investigated and developed software component technology for high-performance parallel scientific computing to address problems of complexity, re-use, and interoperability for laboratory software. Component technology is an extension of scripting and object-oriented software development techniques that specifically focuses on the needs of software interoperability. Component approaches based on CORBA, COM, and Java technologies are widely used in industry; however, they do not support massively parallel applications in science and engineering. Our research focused on the unique requirements of scientific computing on ASCI-class machines, such as fast in-process connections among components, language interoperability for scientific languages, and data distribution support for massively parallel SPMD components.

  2. Mario Bunge's Scientific Realism

    NASA Astrophysics Data System (ADS)

    Cordero, Alberto

    2012-10-01

    This paper presents and comments on Mario Bunge's scientific realism. After a brief introduction in Sects. 1 and 2 outlines Bunge's conception of realism. Focusing on the case of quantum mechanics, Sect. 3 explores how his approach plays out for problematic theories. Section 4 comments on Bunge's project against the background of the current debate on realism in contemporary analytic philosophy.

  3. Scientific and Technical English.

    ERIC Educational Resources Information Center

    Vaclavik, Jaroslav

    Technical English differs from everyday English because of the specialized contexts in which it is used and because of the specialized interests of scientists and engineers. This text provides exercises in technical and scientific exposition in the following fields: mathematics, physics, temperature effects, mechanics, dynamics, conservation of…

  4. Erastosthenes in Scientific Garb.

    ERIC Educational Resources Information Center

    DiVincenzo, Robert M.

    1983-01-01

    How mathematics subject matter can be enhanced through the scientific reasoning method, how this integration can be achieved, adaptations needed for a modified approach, and resulting attainments are all considered. Prime numbers using the Sieve of Erastosthenes are the vehicle through which the approach is described. (MNS)

  5. Mario Bunge's Scientific Realism

    ERIC Educational Resources Information Center

    Cordero, Alberto

    2012-01-01

    This paper presents and comments on Mario Bunge's scientific realism. After a brief introduction in Sects. 1 and 2 outlines Bunge's conception of realism. Focusing on the case of quantum mechanics, Sect. 3 explores how his approach plays out for problematic theories. Section 4 comments on Bunge's project against the background of the current…

  6. [Scientific sex education].

    PubMed

    1977-01-01

    Sex education should help men and women to realize themselves to the complete fullness of their personality; it should teach respect and comprehension toward life, women, and the family. Sex education can modify those traditional attitudes related to family and society which too often result in irresponsible paternity; sex education should be integrated into the teaching of other scientific disciplines. PMID:12309624

  7. Scientific and Artistic Authority

    NASA Astrophysics Data System (ADS)

    Eriksson, S. C.

    2012-12-01

    The differences and similarities between science and art are commonly discussed in various disciplines, e.g. collective versus individual, truth versus imagination, fact versus fiction, and more. Both art and science involve communication. Both artists and scientists have responsibilities of integrity in the arena of intellectual property. However, an artist has a primary responsibility to his/her personal artistic vision and craft. A scientist has a very clearly defined responsibility to scientific method as a collective practice, i.e. generally accepted scientific knowledge, norms of data collection and analysis as well as norms of communication. In presenting a work of art to an audience, it is accepted that different people will interpret the art through different lens. In science communication, we hope that the audience's understanding is in line with scientific interpretation. When science and art meet, how do we come to an understanding of what the intended message should be and how it should or must be received. Accuracy in fact is important in science, as is accuracy of the message whether it is a process, model, image or story. How do we mediate this tension in collaborative projects? How do we celebrate the artistic nature of an artwork based on science when there is tension between the artistic merit and the scientific content? Authority of the artist, scientist, and organization must be satisfied.

  8. Ethics and Scientific Publication

    ERIC Educational Resources Information Center

    Benos, Dale J.; Fabres, Jorge; Farmer, John; Gutierrez, Jessica P.; Hennessy, Kristin; Kosek, David; Lee, Joo Hyoung; Olteanu, Dragos; Russell, Tara; Wang, Kai

    2005-01-01

    This article summarizes the major categories of ethical violations encountered during submission, review, and publication of scientific articles. We discuss data fabrication and falsification, plagiarism, redundant and duplicate publication, conflict of interest, authorship, animal and human welfare, and reviewer responsibility. In each section,…

  9. Professional Scientific Blog

    ERIC Educational Resources Information Center

    Beke, Tamás

    2009-01-01

    The professional blog is a weblog that on the whole meets the requirements of scientific publication. In my opinion it bears a resemblance to digital notice boards, where the competent specialists of the given branch of science can place their ideas, questions, possible solutions and can raise problems. Its most important function can be…

  10. Serendipity and Scientific Discovery.

    ERIC Educational Resources Information Center

    Rosenman, Martin F.

    1988-01-01

    The discovery of penicillin is cited in a discussion of the role of serendipity as it relates to scientific discovery. The importance of sagacity as a personality trait is noted. Successful researchers have questioning minds, are willing to view data from several perspectives, and recognize and appreciate the unexpected. (JW)

  11. Program Supports Scientific Visualization

    NASA Technical Reports Server (NTRS)

    Keith, Stephan

    1994-01-01

    Primary purpose of General Visualization System (GVS) computer program is to support scientific visualization of data generated by panel-method computer program PMARC_12 (inventory number ARC-13362) on Silicon Graphics Iris workstation. Enables user to view PMARC geometries and wakes as wire frames or as light shaded objects. GVS is written in C language.

  12. Assessing Scientific Performance.

    ERIC Educational Resources Information Center

    Weiner, John M.; And Others

    1984-01-01

    A method for assessing scientific performance based on relationships displayed numerically in published documents is proposed and illustrated using published documents in pediatric oncology for the period 1979-1982. Contributions of a major clinical investigations group, the Childrens Cancer Study Group, are analyzed. Twenty-nine references are…

  13. Framing for Scientific Argumentation

    ERIC Educational Resources Information Center

    Berland, Leema K.; Hammer, David

    2012-01-01

    In recent years, research on students' scientific argumentation has progressed to a recognition of nascent resources: Students can and do argue when they experience the need and possibility of persuading others who may hold competing views. Our purpose in this article is to contribute to this progress by applying the perspective of framing to the…

  14. Scientific Imagination in Literature.

    ERIC Educational Resources Information Center

    Stableford, Brian M.

    1978-01-01

    Discusses the conflict between the religious and scientific imaginations as existing between the intellectual realms of unquestioning faith and constant questioning. Relates this conflict to writers of the seventeenth and eighteenth centuries, e.g., Bacon, Kepler, Wilkins, Godwin, Harrington, Campanella, Cyrano, Le Bret, Defoe, Swift, Voltiare,…

  15. Is risk analysis scientific?

    PubMed

    Hansson, Sven Ove; Aven, Terje

    2014-07-01

    This article discusses to what extent risk analysis is scientific in view of a set of commonly used definitions and criteria. We consider scientific knowledge to be characterized by its subject matter, its success in developing the best available knowledge in its fields of study, and the epistemic norms and values that guide scientific investigations. We proceed to assess the field of risk analysis according to these criteria. For this purpose, we use a model for risk analysis in which science is used as a base for decision making on risks, which covers the five elements evidence, knowledge base, broad risk evaluation, managerial review and judgment, and the decision; and that relates these elements to the domains experts and decisionmakers, and to the domains fact-based or value-based. We conclude that risk analysis is a scientific field of study, when understood as consisting primarily of (i) knowledge about risk-related phenomena, processes, events, etc., and (ii) concepts, theories, frameworks, approaches, principles, methods and models to understand, assess, characterize, communicate, and manage risk, in general and for specific applications (the instrumental part). PMID:24919396

  16. Scientific Inquiry 'R' Us.

    ERIC Educational Resources Information Center

    Bourdeau, Virginia D.

    2002-01-01

    Describes the role that informal interpretative programs and facilities can play in providing inquiry-oriented science experiences. Presents two examples of scientific inquiry programs: investigating wetlands and investigating density. In both examples, participants formulate questions, collect data, and attempt to answer their own questions. (DLH)

  17. Scientific Discovery for All

    ERIC Educational Resources Information Center

    Zaikowski, Lori; Lichtman, Paul; Quarless, Duncan

    2007-01-01

    The scientific discovery process comes alive for 70 minority students each year at Uniondale High School in New York where students have won top awards for "in-house" projects. Uniondale High School is in a middle-income school district where over 95% of students are from minority groups. Founded in 2000, the Uniondale High School Research Program…

  18. Scientific and Technical Education.

    ERIC Educational Resources Information Center

    Balzer, Harley D.

    1982-01-01

    Discusses scientific and technical education in the Soviet Union (based in part on extensive interviews with Soviet scientists and engineers), focusing on system of secondary education, preparing students for advanced study, renewed emphasis on specialized secondary schools, higher education/training, and future developments. (Author/JN)

  19. Turning Scientific Presentations into Stories

    ERIC Educational Resources Information Center

    Aruffo, Christopher

    2015-01-01

    To increase students' confidence in giving scientific presentations, students were shown how to present scientific findings as a narrative story. Students who were preparing to give a scientific talk attended a workshop in which they were encouraged to experience the similarities between telling a personal anecdote and presenting scientific data.…

  20. Report of the American College of Cardiology (ACC) Scientific Sessions 2016, Chicago.

    PubMed

    Mano, Toshiaki; Yamamoto, Kazuhiro

    2016-05-25

    The 65(th)Annual Scientific Sessions of the American College of Cardiology (ACC) were held at McCormick Place, Chicago, from April 2-4, 2016. The ACC Scientific Sessions are one of the 2 major scientific cardiology meetings in the USA and one of the major scientific meetings of cardiology in the world. It had an attendance of 18,769 and over 2,000 oral and poster abstracts, including 8 late-breaking clinical trials. This report presents the key presentations and the highlights from the ACC Scientific Sessions 2016 in Chicago. (Circ J 2016; 80: 1308-1313). PMID:27151567

  1. Predicting Scholars' Scientific Impact

    PubMed Central

    Mazloumian, Amin

    2012-01-01

    We tested the underlying assumption that citation counts are reliable predictors of future success, analyzing complete citation data on the careers of scientists. Our results show that i) among all citation indicators, the annual citations at the time of prediction is the best predictor of future citations, ii) future citations of a scientist's published papers can be predicted accurately ( for a 1-year prediction, ) but iii) future citations of future work are hardly predictable. PMID:23185311

  2. Earth Sciences Division annual report 1989

    SciTech Connect

    Not Available

    1990-06-01

    This Annual Report presents summaries of selected representative research activities from Lawrence Berkeley Laboratory grouped according to the principal disciplines of the Earth Sciences Division: Reservoir Engineering and Hydrology, Geology and Geochemistry, and Geophysics and Geomechanics. We are proud to be able to bring you this report, which we hope will convey not only a description of the Division's scientific activities but also a sense of the enthusiasm and excitement present today in the Earth Sciences.

  3. Theory, Modeling and Simulation Annual Report 2000

    SciTech Connect

    Dixon, David A; Garrett, Bruce C; Straatsma, TP; Jones, Donald R; Studham, Scott; Harrison, Robert J; Nichols, Jeffrey A

    2001-11-01

    This annual report describes the 2000 research accomplishments for the Theory, Modeling, and Simulation (TM and S) directorate, one of the six research organizations in the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) at Pacific Northwest National Laboratory (PNNL). EMSL is a U.S. Department of Energy (DOE) national scientific user facility and is the centerpiece of the DOE commitment to providing world-class experimental, theoretical, and computational capabilities for solving the nation's environmental problems.

  4. Theory, Modeling and Simulation Annual Report 2000

    SciTech Connect

    Dixon, David A.; Garrett, Bruce C.; Straatsma, Tp; Jones, Donald R.; Studham, Ronald S.; Harrison, Robert J.; Nichols, Jeffrey A.

    2001-11-01

    This annual report describes the 2000 research accomplishments for the Theory, Modeling, and Simulation (TM&S) directorate, one of the six research organizations in the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) at Pacific Northwest National Laboratory (PNNL). EMSL is a U.S. Department of Energy (DOE) national scientific user facility and is the centerpiece of the DOE commitment to providing world-class experimental, theoretical, and computational capabilities for solving the nation's environmental problems.

  5. Observatory ends scientific investigations

    NASA Astrophysics Data System (ADS)

    Bell, Peter M.

    The Orbiting Astronomical Observatory (OAO-3), which was instrumental in the discovery of the first suspected black hole, wound up its scientific investigation at the end of 1980. Spacecraft science operations were terminated after 8½ years of operation. Named Copernicus, OAO-3 performed consistently beyond design specifications and 7½ years beyond project requirements. Its performance profile, according to the NASA-Goddard engineers and scientists, was ‘astonishing.’While formal scientific investigations were ended December 31, a series of engineering tests are still being made until February 15. At that time, all contact with the spacecraft will end. Project engineers are uncertain whether Copernicus will orient itself permanently toward the sun, begin a permanent orbital tumbling action, or a variation of both.

  6. Scientific Resource EXplorer

    NASA Astrophysics Data System (ADS)

    Xing, Z.; Wormuth, A.; Smith, A.; Arca, J.; Lu, Y.; Sayfi, E.

    2014-12-01

    Inquisitive minds in our society are never satisfied with curatedimages released by a typical public affairs office. They always want tolook deeper and play directly on original data. However, most scientificdata products are notoriously hard to use. They are immensely large,highly distributed and diverse in format. In this presentation,we will demonstrate Resource EXplorer (REX), a novel webtop applicationthat allows anyone to conveniently explore and visualize rich scientificdata repositories, using only a standard web browser. This tool leverageson the power of Webification Science (w10n-sci), a powerful enabling technologythat simplifies the use of scientific data on the web platform.W10n-sci is now being deployed at an increasing number of NASA data centers,some of which are the largest digital treasure troves in our nation.With REX, these wonderful scientific resources are open for teachers andstudents to learn and play.

  7. Toward Scientific Numerical Modeling

    NASA Technical Reports Server (NTRS)

    Kleb, Bil

    2007-01-01

    Ultimately, scientific numerical models need quantified output uncertainties so that modeling can evolve to better match reality. Documenting model input uncertainties and verifying that numerical models are translated into code correctly, however, are necessary first steps toward that goal. Without known input parameter uncertainties, model sensitivities are all one can determine, and without code verification, output uncertainties are simply not reliable. To address these two shortcomings, two proposals are offered: (1) an unobtrusive mechanism to document input parameter uncertainties in situ and (2) an adaptation of the Scientific Method to numerical model development and deployment. Because these two steps require changes in the computational simulation community to bear fruit, they are presented in terms of the Beckhard-Harris-Gleicher change model.

  8. Scientific publications in Nepal.

    PubMed

    Magar, A

    2012-09-01

    Scientific publications have become a mainstay of communication among readers, academicians, researchers and scientists worldwide. Although, its existence dates back to 17 th century in the West, Nepal is still struggling to take few steps towards improving its local science for last 50 years. Since the start of the first medical journal in 1963, the challenges remains as it were decades back regarding role of authors, peer reviewers, editors and even publishers in Nepal. Although, there has been some development in terms of the number of articles being published and appearances of the journals, yet there is a long way to go. This article analyzes the past and present scenario, and future perspective for scientific publications in Nepal. PMID:23281460

  9. Sherlock Holmes: scientific detective.

    PubMed

    Snyder, Laura J

    2004-09-01

    Sherlock Holmes was intended by his creator, Arthur Conan Doyle, to be a 'scientific detective'. Conan Doyle criticized his predecessor Edgar Allan Poe for giving his creation - Inspector Dupin - only the 'illusion' of scientific method. Conan Doyle believed that he had succeeded where Poe had failed; thus, he has Watson remark that Holmes has 'brought detection as near an exact science as it will ever be brought into the world.' By examining Holmes' methods, it becomes clear that Conan Doyle modelled them on certain images of science that were popular in mid- to late-19th century Britain. Contrary to a common view, it is also evident that rather than being responsible for the invention of forensic science, the creation of Holmes was influenced by the early development of it. PMID:15350761

  10. Scientific Software Component Technology

    SciTech Connect

    Kohn, S.; Dykman, N.; Kumfert, G.; Smolinski, B.

    2000-02-16

    We are developing new software component technology for high-performance parallel scientific computing to address issues of complexity, re-use, and interoperability for laboratory software. Component technology enables cross-project code re-use, reduces software development costs, and provides additional simulation capabilities for massively parallel laboratory application codes. The success of our approach will be measured by its impact on DOE mathematical and scientific software efforts. Thus, we are collaborating closely with library developers and application scientists in the Common Component Architecture forum, the Equation Solver Interface forum, and other DOE mathematical software groups to gather requirements, write and adopt a variety of design specifications, and develop demonstration projects to validate our approach. Numerical simulation is essential to the science mission at the laboratory. However, it is becoming increasingly difficult to manage the complexity of modern simulation software. Computational scientists develop complex, three-dimensional, massively parallel, full-physics simulations that require the integration of diverse software packages written by outside development teams. Currently, the integration of a new software package, such as a new linear solver library, can require several months of effort. Current industry component technologies such as CORBA, JavaBeans, and COM have all been used successfully in the business domain to reduce software development costs and increase software quality. However, these existing industry component infrastructures will not scale to support massively parallel applications in science and engineering. In particular, they do not address issues related to high-performance parallel computing on ASCI-class machines, such as fast in-process connections between components, language interoperability for scientific languages such as Fortran, parallel data redistribution between components, and massively

  11. Soviets seek scientific exchange

    NASA Astrophysics Data System (ADS)

    GEOS-A, associated with the Soviet Union's Institute of Earth Physics, is seeking to promote exchange between Soviet and Western geophysicists. GEOS-A is a nonprofit, private organization formed by specialists from the U.S.S.R. Academy of Scientists.GEOS-A aims to promote the transfer of academic research results to industry and education. It also seeks to stimulate international scientific exchange and to support independent nongovernmental programs and expertise in geophysics and ecology. The organization would like to cooperate with Western universities in exchanging students and young scientists and in building scientific relationships between the two countries. This would include inviting students and young specialists for collaborative scientific research, consultations, language practice, and graduate study in any institute of the U.S.S.R. Academy of Sciences. Participants would live in rented private apartments in downtown Moscow for approximately one week to several months. All living expenses would be covered at a rate higher than the academy's standard one (unfortunately travel to and from the Soviet Union cannot be covered).

  12. Heliophysics as a Scientific Discipline

    NASA Astrophysics Data System (ADS)

    Greb, K.

    2015-12-01

    Heliophysics is a developing scientific discipline integrating studies of the Sun's variability, the surrounding heliosphere, and climate environments. Over the past few centuries our understanding of how the Sun drives space weather and climate on the Earth and other planets has advanced at an ever-increasing rate. NASA Living With a Star and the UCAR Visiting Scientist Progams sponsor the annual Heliophysics Summer Schools to build the next generation of scientists in this emerging field. The highly successful series of the summer schools (commencing 2007) trains a select group of graduate students, postdoctoral fellows and university faculty to learn and develop the science of heliophysics as a broad, coherent discipline that reaches in space from the Earth's troposphere to the depths of the Sun, and in time from the formation of the solar system to the distant future. Now in its tenth year, the School has resulted in the publication of five Heliophysics textbooks now being used at universities worldwide. The books provide a foundational reference for researchers in space physics, solar physics, aeronomy, space weather, planetary science and climate science, astrophysics, plasma physics,. In parallel, the School also developed the complementary materials that support teaching of heliophysics at both graduate and undergraduate levels. The Jack Eddy Postdoctoral Fellowship Program matches newly graduated postdoctorates with hosting mentors for the purpose of training the next generation researchers needed in heliophysics. The fellowships are for two years, and any U.S. university or research lab may apply to host a fellow. Two major topics of focus for the program are the science of space weather and of the Sun-climate connection. Since the goal of this fellowship program is to train Sun-Earth system researchers, preference is also given to research projects that cross the traditional heliophysics subdomains of the Sun, heliosphere, magnetosphere, and ionosphere

  13. Polar Research Board annual report, 1987 and future plans

    SciTech Connect

    Not Available

    1988-01-01

    This annual report describes the Polar Research Board, its origin and objectives, its work and plans, and its principle activities and accomplishments during calendar year 1987. The Overview presents a concise summary of the various aspects of the Board's program and of its responsibilities as US National Committee for the Scientific Committee on Antarctic Research (SCAR) of the International Council of Scientific Unins. Arctic and Antarctic activities are described.

  14. Polar Research Board annual report, 1987 and future plans

    SciTech Connect

    Not Available

    1988-12-31

    This annual report describes the Polar Research Board, its origin and objectives, its work and plans, and its principle activities and accomplishments during calendar year 1987. The Overview presents a concise summary of the various aspects of the Board`s program and of its responsibilities as US National Committee for the Scientific Committee on Antarctic Research (SCAR) of the International Council of Scientific Unins. Arctic and Antarctic activities are described.

  15. The Scientific Case against Astrology.

    ERIC Educational Resources Information Center

    Kelly, Ivan

    1980-01-01

    Discussed is the lack of a scientific foundation and scientific evidence favoring astrology. Included are several research studies conducted to examine astrological tenets which yield generally negative results. (Author/DS)

  16. 'El Capitan's' Scientific Gems

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This mosaic of images taken by the panoramic camera onboard the Mars Exploration Rover Opportunity shows the rock region dubbed 'El Capitan,' which lies within the larger outcrop near the rover's landing site. 'El Capitan' is being studied in great detail using the scientific instruments on the rover's arm; images from the panoramic camera help scientists choose the locations for this compositional work. The millimeter-scale detail of the lamination covering these rocks can be seen. The face of the rock to the right of the mosaic may be a future target for grinding with the rover's rock abrasion tool.

  17. Advances in scientific visualization

    SciTech Connect

    Max, N.; Crawfis, R. |

    1995-01-11

    This paper discusses scientific visualization of scalar and vector fields, particularly relating to clouds and climate modeling. One cloud rendering method applies a 3-D texture to cloudiness contour surfaces, to simulate a view from outer space. The texture is advected by the wind flow, so that it follows the cloud motion. Another technique simulates multiple scattering of incident light from the sun and sky. This paper also presents a simulation of the microscopic cross-bridge motion which powers muscle contraction. It was rendered by ray-tracing contour surfaces of summed Gaussian ellipsoids approximating the actin and myosin protein shapes.

  18. Preliminary estimates of annual agricultural pesticide use for counties of the conterminous United States, 2013

    USGS Publications Warehouse

    Baker, Nancy T.

    2015-01-01

    Thelin, G.P., and Stone, W.W., 2013, Estimation of annual agricultural pesticide use for counties of the conterminous United States, 1992–2009: U.S. Geological Survey Scientific Investigations Report 2013–5009, 54 p.

  19. Scientific Language: Wherein Its Mystique?

    ERIC Educational Resources Information Center

    Randall, Alice Fracker

    In recent years both scientists and laypeople have viewed with dismay the notion that science seems mysteriously different from other areas of human concern. Scientific language is part of the mystique. Yet scientific language is human language before it is science. The mystique that people ascribe to scientific language is of their own making,…

  20. The Scientific Competitiveness of Nations

    PubMed Central

    Cimini, Giulio; Gabrielli, Andrea; Sylos Labini, Francesco

    2014-01-01

    We use citation data of scientific articles produced by individual nations in different scientific domains to determine the structure and efficiency of national research systems. We characterize the scientific fitness of each nation—that is, the competitiveness of its research system—and the complexity of each scientific domain by means of a non-linear iterative algorithm able to assess quantitatively the advantage of scientific diversification. We find that technological leading nations, beyond having the largest production of scientific papers and the largest number of citations, do not specialize in a few scientific domains. Rather, they diversify as much as possible their research system. On the other side, less developed nations are competitive only in scientific domains where also many other nations are present. Diversification thus represents the key element that correlates with scientific and technological competitiveness. A remarkable implication of this structure of the scientific competition is that the scientific domains playing the role of “markers” of national scientific competitiveness are those not necessarily of high technological requirements, but rather addressing the most “sophisticated” needs of the society. PMID:25493626

  1. The Scientific Competitiveness of Nations.

    PubMed

    Cimini, Giulio; Gabrielli, Andrea; Sylos Labini, Francesco

    2014-01-01

    We use citation data of scientific articles produced by individual nations in different scientific domains to determine the structure and efficiency of national research systems. We characterize the scientific fitness of each nation-that is, the competitiveness of its research system-and the complexity of each scientific domain by means of a non-linear iterative algorithm able to assess quantitatively the advantage of scientific diversification. We find that technological leading nations, beyond having the largest production of scientific papers and the largest number of citations, do not specialize in a few scientific domains. Rather, they diversify as much as possible their research system. On the other side, less developed nations are competitive only in scientific domains where also many other nations are present. Diversification thus represents the key element that correlates with scientific and technological competitiveness. A remarkable implication of this structure of the scientific competition is that the scientific domains playing the role of "markers" of national scientific competitiveness are those not necessarily of high technological requirements, but rather addressing the most "sophisticated" needs of the society. PMID:25493626

  2. Advancing Scientific Research in Education

    ERIC Educational Resources Information Center

    Towne, Lisa, Ed.; Wise, Lauress L., Ed.; Winters, Tina M., Ed.

    2004-01-01

    Transforming education into an evidence-based field depends in no small part on a strong base of scientific knowledge to inform educational policy and practice. Advancing Scientific Research in Education makes select recommendations for strengthening scientific education research and targets federal agencies, professional associations, and…

  3. Scientific ballooning opportunities

    NASA Astrophysics Data System (ADS)

    Peacock, D.

    The National Science Foundation and the National Aeronautics and Space Administration are exploring the, possibilities of a joint balloon program in Antarctica. Over the years there have been many successful small balloons launched from Antarctica for research on topics such as meteorology, atmospheric chemistry, magnetospheric physics, and astrophysics. Recently, a large balloon (and payload) was successfully launched from McMurdo.In response to this growing interest, NSF hosted a 1-day workshop on Scientific Ballooning in Antarctica on March 27. This was well received, as evidenced by the attendance of some 40-50 scientists. At a follow-up meeting on June 14, 1988, attended by P. Wilkness, Division Director, Polar Programs, NSF, and S. Shawhan, Division Director, Space Physics, NASA, it was decided to solicit community input in the form of brief letters (one or two pages). Therefore if you have aspirations for balloon activities in Antarctica within the next few years, please send a brief description of your plans, including scientific objectives, time frame, launch site(s), logistical requirements, budget estimates (excluding logistics), and special needs, if any. Send this material to J . Lynch, Program Manager, Polar Atmospheric Sciences, Division of Polar Programs, National Science Foundation, 1800 G St., N.W., Washington, DC 20550. Send a copy to S. Shawhan, Director, Space Physics Division, NASA Headquarters, Washington, DC 20546.

  4. IAHS Third Scientific Assembly

    NASA Astrophysics Data System (ADS)

    The International Association of Hydrological Sciences (IAHS) convened its Third Scientific Assembly in Baltimore, Md., May 10-19, 1989. The Assembly was attended by about 450 scientists and engineers. The attendance was highest from the U.S., as could be expected; 37 were from Canada; 22 each, Netherlands and United Kingdom; 14, Italy; 12, China; 10, Federal Republic of Germany; 8 each from France, the Republic of South Africa, and Switzerland; 7, Austria; 6 each, Finland and Japan; others were scattered among the remainder of 48 countries total.one of the cosponsors and also handled business matters for the Assembly. Other cosponsors included the International Association of Meteorology and Atmospheric Physics (IAMAP), United Nations Environmental Program (UNEP), United Nations Educational, Scientific, and Cultural Organization (UNESCO), World Meteorological Organization (WMO), and U.K. Overseas Development Authority (ODA). U.S. federal agencies serving as cosponsors included the Environmental Protection Agency, National Aeronautics and Space Administration, National Science Foundation, National Weather Service, Department of Agriculture, Department of State, and U.S. Geological Survey.

  5. Evolution of the scientific paper

    SciTech Connect

    Harmon, J.E.

    1992-01-01

    The first papers reporting original research results in technical periodicals and proceedings appeared in the late 17th century. Since that time, the typical scientific paper has evolved from a fairly simple document, accessible to a general audience, to a much more complex one, aimed at a specialized audience. The purpose of this article is to give an overview of what the first scientific papers were like and how they evolved to their present form and style. To facilitate this discussion, the scientific paper's development has arbitrarily been divided into four stages: the origin and formative years of the scientific paper (1665-1765), emergence of scientific papers written for specialized publications (1765-1865), development of the modem scientific paper (1865-1965), and hyperspecialization and computerization of the modem scientific paper (1965- ).

  6. Evolution of the scientific paper

    SciTech Connect

    Harmon, J.E.

    1992-09-01

    The first papers reporting original research results in technical periodicals and proceedings appeared in the late 17th century. Since that time, the typical scientific paper has evolved from a fairly simple document, accessible to a general audience, to a much more complex one, aimed at a specialized audience. The purpose of this article is to give an overview of what the first scientific papers were like and how they evolved to their present form and style. To facilitate this discussion, the scientific paper`s development has arbitrarily been divided into four stages: the origin and formative years of the scientific paper (1665-1765), emergence of scientific papers written for specialized publications (1765-1865), development of the modem scientific paper (1865-1965), and hyperspecialization and computerization of the modem scientific paper (1965-?).

  7. Report of the American College of Cardiology (ACC) Scientific Sessions 2015, San Diego.

    PubMed

    Murohara, Toyoaki

    2015-01-01

    The 64th Annual Scientific Sessions and Exposition of the American College of Cardiology (ACC) were held at the San Diego Convention Center from March 14-16, 2015. The ACC Scientific Sessions are 1 of 2 major scientific cardiology meetings in the United States, with nearly 20,000 attendees, including 15,000 cardiovascular professionals. There were over 2,100 oral and poster abstracts, and more than 15 late-breaking clinical trials (LBCTs) abstructs. This report presents the highlights and several key presentations, especially the LBCTs, from the ACC Scientific Sessions 2015. I hope this review will help cardiologists update to the latest information. PMID:25959559

  8. Dishonesty in scientific research.

    PubMed

    Mazar, Nina; Ariely, Dan

    2015-11-01

    Fraudulent business practices, such as those leading to the Enron scandal and the conviction of Bernard Madoff, evoke a strong sense of public outrage. But fraudulent or dishonest actions are not exclusive to the realm of big corporations or to evil individuals without consciences. Dishonest actions are all too prevalent in everyone's daily lives, because people are constantly encountering situations in which they can gain advantages by cutting corners. Whether it's adding a few dollars in value to the stolen items reported on an insurance claim form or dropping outlier data points from a figure to make a paper sound more interesting, dishonesty is part of the human condition. Here, we explore how people rationalize dishonesty, the implications for scientific research, and what can be done to foster a culture of research integrity. PMID:26524587

  9. Ben Franklin's Scientific Amusements

    NASA Astrophysics Data System (ADS)

    Herschbach, Dudley

    2003-04-01

    As an American icon, Benjamin Franklin is often portrayed as wise and canny in business and politics, earnestly pursuing and extolling diligence, sensible conduct, pragmatism, and good works. Also legendary are some of his inventions, particularly the lightning rod, bifocals, and an efficient wood-burning stove. The iconic image is misleading in major respects. Today, surprisingly few people appreciate that, in the 18th century, Franklin was greatly esteemed throughout Europe as a scientist (termed then a "natural philosopher.") He was hailed as the "Newton of Electricity." Indeed, until Franklin, electricity seemed more mysterious than had gravity in Newton's time, and lightning was considered the wrath of God. By his own account, Franklin's studies of electricity and many other phenomena were prompted not by practical aims, but by his playful curiosity--which often became obsessive. Also not generally appreciated is the importance of Franklin's scientific reputation in enhancing his efforts to obtain French support for the American Revolution.

  10. Ethics in Scientific Publishing

    NASA Astrophysics Data System (ADS)

    Sage, Leslie J.

    2012-08-01

    We all learn in elementary school not turn in other people's writing as if it were our own (plagiarism), and in high school science labs not to fake our data. But there are many other practices in scientific publishing that are depressingly common and almost as unethical. At about the 20 percent level authors are deliberately hiding recent work -- by themselves as well as by others -- so as to enhance the apparent novelty of their most recent paper. Some people lie about the dates the data were obtained, to cover up conflicts of interest, or inappropriate use of privileged information. Others will publish the same conference proceeding in multiple volumes, or publish the same result in multiple journals with only trivial additions of data or analysis (self-plagiarism). These shady practices should be roundly condemned and stopped. I will discuss these and other unethical actions I have seen over the years, and steps editors are taking to stop them.

  11. Scientific developments ISFD3

    USGS Publications Warehouse

    Schropp, M.H.I.; Soong, T.W.

    2006-01-01

    Highlights, trends, and consensus from the 63 papers submitted to the Scientific Developments theme of the Third International Symposium on Flood Defence (ISFD) are presented. Realizing that absolute protection against flooding can never be guaranteed, trends in flood management have shifted: (1) from flood protection to flood-risk management, (2) from reinforcing structural protection to lowering flood levels, and (3) to sustainable management through integrated problem solving. Improved understanding of watershed responses, climate changes, applications of GIS and remote-sensing technologies, and advanced analytical tools appeared to be the driving forces for renewing flood-risk management strategies. Technical competence in integrating analytical tools to form the basin wide management systems are demonstrated by several large, transnation models. However, analyses from social-economic-environmental points of view are found lag in general. ?? 2006 Taylor & Francis Group.

  12. Final Scientific EFNUDAT Workshop

    ScienceCinema

    None

    2011-10-06

    The Final Scientific EFNUDAT Workshop - organized by the CERN/EN-STI group on behalf of n_TOF Collaboration - will be held at CERN, Geneva (Switzerland) from 30 August to 2 September 2010 inclusive.EFNUDAT website: http://www.efnudat.euTopics of interest include: Data evaluationCross section measurementsExperimental techniquesUncertainties and covariancesFission propertiesCurrent and future facilities  International Advisory Committee: C. Barreau (CENBG, France)T. Belgya (IKI KFKI, Hungary)E. Gonzalez (CIEMAT, Spain)F. Gunsing (CEA, France)F.-J. Hambsch (IRMM, Belgium)A. Junghans (FZD, Germany)R. Nolte (PTB, Germany)S. Pomp (TSL UU, Sweden) Workshop Organizing Committee: Enrico Chiaveri (Chairman)Marco CalvianiSamuel AndriamonjeEric BerthoumieuxCarlos GuerreroRoberto LositoVasilis Vlachoudis Workshop Assistant: Géraldine Jean

  13. Annual Energy Review, 2008

    SciTech Connect

    2009-06-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, and international energy; financial and environment indicators; and data unit conversions.

  14. The National Eye Institute Annual Report: FY 1974.

    ERIC Educational Resources Information Center

    National Eye Inst. (DHEW/PHS), Bethesda, MD.

    Presented is an annual report of research and supported by the National Eye Institute (NEI) during the 1974 fiscal year. It is explained that the purpose of NEI research programs is to develop scientific knowledge which can be applied to the improved prevention, diagnosis, and treatment of visual disorders. The section on extramural and…

  15. Abstracts of Presentations--Seventh Annual 4S Meeting.

    ERIC Educational Resources Information Center

    4S - Society for Social Studies of Science, 1982

    1982-01-01

    Presents abstracts of papers for the Seventh Annual Meeting of the Society for the Social Studies of Science. Topics include, among others, rhetoric of a scientific controversy; recombinant DNA; science and social justice; patent citation analysis; national need and peer-review process; and scientism, romanticism, and social realist images of…

  16. Third Annual David Derse Memorial Lecture and Award | Poster

    Cancer.gov

    By Anne Arthur, Guest Writer The Third Annual David Derse Memorial Lecture and Award presentation was held on Nov. 18 at NCI at Frederick to honor the outstanding research accomplishments of David Derse, Ph.D., and to stimulate the exchange of innovative ideas that Derse was well known for promoting throughout his scientific career.

  17. Sources Sought for Innovative Scientific Instrumentation for Scientific Lunar Rovers

    NASA Technical Reports Server (NTRS)

    Meyer, C.

    1993-01-01

    Lunar rovers should be designed as integrated scientific measurement systems that address scientific goals as their main objective. Scientific goals for lunar rovers are presented. Teleoperated robotic field geologists will allow the science team to make discoveries using a wide range of sensory data collected by electronic 'eyes' and sophisticated scientific instrumentation. rovers need to operate in geologically interesting terrain (rock outcrops) and to identify and closely examine interesting rock samples. Enough flight-ready instruments are available to fly on the first mission, but additional instrument development based on emerging technology is desirable. Various instruments that need to be developed for later missions are described.

  18. [Reporting of scientific misconduct in health care research].

    PubMed

    Klasen, E C; Overbeke, A J P M

    2002-08-31

    The incidence of scientific dishonesty in the Netherlands is not known, yet experiences at both the NWO (the Netherlands Organization for Scientific Research) and Nederlands Tijdschrift voor Geneeskunde (Dutch Journal of Medicine) indicate that there must be several cases per year. For scientific fraud to be prevented students and researchers should receive thorough teaching, and in research laboratories an emphasis should be placed upon integrity. The Academic Medical Centre in Amsterdam has published a research protocol which is perfect for internal use. The Royal Netherlands Academy of Arts and Sciences publishes brochures on good research practice for researchers, teachers and students. The NWO and the Vereniging van Universiteiten (Dutch Association of Universities) have set up a committee for scientific integrity to function as a fallback mechanism and to assess the institutional procedures or to repeat the inquiries. As healthcare research institutions other than universities are involved since authorities are not always objective, an independent committee has been established to assess complaints about scientific dishonesty, the Scientific Integrity Health Research. Like the Committee on Publication Ethics it will publish its cases anonymously on an annual basis. Its judgments will be communicated to the people involved and the proper authorities. PMID:12233155

  19. Nuclear Chemistry Division annual report FY83

    SciTech Connect

    Struble, G.

    1983-01-01

    The purpose of the annual reports of the Nuclear Chemistry Division is to provide a timely summary of research activities pursued by members of the Division during the preceding year. Throughout, details are kept to a minimum; readers desiring additional information are encouraged to read the referenced documents or contact the authors. The Introduction presents an overview of the Division's scientific and technical programs. Next is a section of short articles describing recent upgrades of the Division's major facilities, followed by sections highlighting scientific and technical advances. These are grouped under the following sections: nuclear explosives diagnostics; geochemistry and environmental sciences; safeguards technology and radiation effect; and supporting fundamental science. A brief overview introduces each section. Reports on research supported by a particular program are generally grouped together in the same section. The last section lists the scientific, administrative, and technical staff in the Division, along with visitors, consultants, and postdoctoral fellows. It also contains a list of recent publications and presentations. Some contributions to the annual report are classified and only their abstracts are included in this unclassified portion of the report (UCAR-10062-83/1); the full article appears in the classified portion (UCAR-10062-83/2).

  20. Scientific Teaching Targeting Faculty from Diverse Institutions

    PubMed Central

    Gregg, Christopher S.; Ales, Jo Dale; Pomarico, Steven M.; Wischusen, E. William; Siebenaller, Joseph F.

    2013-01-01

    We offered four annual professional development workshops called STAR (for Scientific Teaching, Assessment, and Resources) modeled after the National Academies Summer Institute (SI) on Undergraduate Education in Biology. In contrast to the SI focus on training faculty from research universities, STAR's target was faculty from community colleges, 2-yr campuses, and public and private research universities. Because of the importance of community colleges and 2-yr institutions as entries to higher education, we wanted to determine whether the SI model can be successfully extended to this broader range of institutions. We surveyed the four cohorts; 47 STAR alumni responded to the online survey. The responses were separated into two groups based on the Carnegie undergraduate instructional program categories, faculty from seven associate's and associate's-dominant institutions (23) and faculty from nine institutions with primarily 4-yr degree programs (24). Both groups expressed the opinion that STAR had a positive impact on teaching, student learning, and engagement. The two groups reported using techniques of formative assessment and active learning with similar frequency. The mix of faculty from diverse institutions was viewed as enhancing the workshop experience. The present analysis indicates that the SI model for training faculty in scientific teaching can successfully be extended to a broad range of higher education institutions. PMID:24006387

  1. Acquisition of Scientific Equipment

    SciTech Connect

    Noland, Lynn

    2014-05-16

    Whitworth University constructed a 63,00 sq. ft. biology and chemistry building which opened in the Fall of 2011. This project provided for new state-of-the-art science instrumentation enabling Whitworth students to develop skills and knowledge that are directly transferable to practical applications thus enhancing Whitworth student's ability to compete and perform in the scientific workforce. Additionally, STEM faculty undertake outreach programs in the area schools, bringing students to our campus to engage in activities with our science students. The ability to work with insturmentation that is current helps to make science exciting for middle school and high school students and gets them thinking about careers in science. 14 items were purchased following the university's purchasing policy, that benefit instruction and research in the departments of biology, chemistry, and health sciences. They are: Cadaver Dissection Tables with Exhaust Chamber and accessories, Research Microscope with DF DIC, Phase and Fluorescence illumination with DP72 Camera, Microscope with Fluorescence, Microcomputer controlled ultracentrifuge, Ultracentrifuge rotor, Variable Temperature steam pressure sterilizer, Alliance APLC System, DNA Speedvac, Gel Cocumentation System, BioPac MP150, Glovebox personal workstation,Lyophilizer, Nano Drop 2000/2000c Spectrophotometer, C02 Incubator.

  2. Scientific Programme Committee

    NASA Astrophysics Data System (ADS)

    2013-02-01

    Scientific Programme Committee A. Blondel, University of Geneva A. Cervera, IFIC M. Dracos, IN2P3 I. Efhymiopoulos, CERN J. Ellis, CERN S. Geer, FNAL R. Garoby, CERN M. Goodman, ANL D. Harris, FNAL T. Hasegawa, KEK P. Huber, Virginia Tech. D. Kaplan, IIT Y.D. Kim, Sejong University H. Kirk, BNL Y. Kuno, Osaka University K. Long, Imperial College N.K. Mondal, TIFR J. Morfin, FNAL Y. Mori, Kyoto University K. Nishikawa, KEK V. Palladino, University of Napoli C. Prior, RAL F.J.P. Soler, University of Glasgow J. Strait, FNAL R. Svoboda, University of California Davis F. Terranova, LN Frascati M. Zisman, LBNL Local Organizing Committee E. Benedetto, CERN/NTUA C. Blanchard, University of Geneva A. Blondel, University of Geneva (co-chair) I. Efthymiopoulos, CERN (co-chair) F. Dufour, University of Geneva F. Girard-Madoux, CERN E. Gschwendtner, CERN A. Korzenev, University of Geneva M. Morer-Olafsen, CERN S. Murphy, University of Geneva G. Prior, CERN G. Wikström, University of Geneva E. Wildner, CERN Sponsors EuCARD European Organization for Nuclear Research (CERN) Swiss Institute for Particle Physics (CHIPP) University of Geneva

  3. Scientific balloons: historical remarks.

    NASA Astrophysics Data System (ADS)

    Ubertini, P.

    The paper is an overview of the Human attempt to fly, from the myth of Daedalus and his son Icarus to the first "aerostatic" experiment by Joseph-Michel and Jaques-Etienne Montgolfier. Then, via a jump of about 200 years, we arrive to the era of the modern stratospheric ballooning that, from the beginning of the last century, have provided a unique flight opportunity for aerospace experiments. In particular, the Italian scientific community has employed stratospheric balloons since the '50s for cosmic rays and high energy astrophysical experiments with initial launches performed from Cagliari Helmas Airport (Sardinia). More recently an almost ideal location was found in the area of Trapani-Milo (Sicily, Italy), were an old abandoned airport was refurbished to be used as a new launch site that became operative at the beginning of the '70s. Finally, we suggest a short reminiscence of the first transatlantic experiment carried out on August 1975 in collaboration between SAS-CNR (Italy) and NSBF-NASA (USA). The reason why the Long Duration Balloon has been recently re-oriented in a different direction is analysed and future perspectives discussed. Finally, the spirit of the balloon launch performed by the Groups lead by Edoardo Amaldi, Livio Scarsi and other Italian pioneers, with payloads looking like "refrigerators" weighting a few tens of kg is intact and the wide participation to the present Workshop is the clear demonstration.

  4. Load Balancing Scientific Applications

    SciTech Connect

    Pearce, Olga Tkachyshyn

    2014-12-01

    The largest supercomputers have millions of independent processors, and concurrency levels are rapidly increasing. For ideal efficiency, developers of the simulations that run on these machines must ensure that computational work is evenly balanced among processors. Assigning work evenly is challenging because many large modern parallel codes simulate behavior of physical systems that evolve over time, and their workloads change over time. Furthermore, the cost of imbalanced load increases with scale because most large-scale scientific simulations today use a Single Program Multiple Data (SPMD) parallel programming model, and an increasing number of processors will wait for the slowest one at the synchronization points. To address load imbalance, many large-scale parallel applications use dynamic load balance algorithms to redistribute work evenly. The research objective of this dissertation is to develop methods to decide when and how to load balance the application, and to balance it effectively and affordably. We measure and evaluate the computational load of the application, and develop strategies to decide when and how to correct the imbalance. Depending on the simulation, a fast, local load balance algorithm may be suitable, or a more sophisticated and expensive algorithm may be required. We developed a model for comparison of load balance algorithms for a specific state of the simulation that enables the selection of a balancing algorithm that will minimize overall runtime.

  5. Collaboratively Sharing Scientific Data

    NASA Astrophysics Data System (ADS)

    Wang, Fusheng; Vergara-Niedermayr, Cristobal

    Scientific research becomes increasingly reliant on multi-disciplinary, multi-institutional collaboration through sharing experimental data. Indeed, data sharing is mandatory by government research agencies such as NIH. The major hurdles for data sharing come from: i) the lack of data sharing infrastructure to make data sharing convenient for users; ii) users’ fear of losing control of their data; iii) difficulty on sharing schemas and incompatible data from sharing partners; and iv) inconsistent data under schema evolution. In this paper, we develop a collaborative data sharing system SciPort, to support consistency preserved data sharing among multiple distributed organizations. The system first provides Central Server based lightweight data integration architecture, so data and schemas can be conveniently shared across multiple organizations. Through distributed schema management, schema sharing and evolution is made possible, while data consistency is maintained and data compatibility is enforced. With this data sharing system, distributed sites can now consistently share their research data and their associated schemas with much convenience and flexibility. SciPort has been successfully used for data sharing in biomedical research, clinical trials and large scale research collaboration.

  6. ISCR FY2005 Annual Report

    SciTech Connect

    Keyes, D E; McGraw, J R

    2006-02-02

    seminar series. The ISCR identifies researchers from the academic community for computer science and computational science collaborations with LLNL and hosts them for both brief and extended visits with the aim of encouraging long-term academic research agendas that address LLNL research priorities. Through these collaborations, ideas and software flow in both directions, and LLNL cultivates its future workforce. The Institute strives to be LLNL's ''eyes and ears'' in the computer and information sciences, keeping the Laboratory aware of and connected to important external advances. It also attempts to be the ''hands and feet'' that carry those advances into the Laboratory and incorporate them into practice. ISCR research participants are integrated into LLNL's Computing Applications and Research (CAR) Department, especially into its Center for Applied Scientific Computing (CASC). In turn, these organizations address computational challenges arising throughout the rest of the Laboratory. Administratively, the ISCR flourishes under LLNL's University Relations Program (URP). Together with the other four institutes of the URP, the ISCR navigates a course that allows LLNL to benefit from academic exchanges while preserving national security. While it is difficult to operate an academic-like research enterprise within the context of a national security laboratory, the results declare the challenges well met and worth the continued effort. The pages of this annual report summarize the activities of the faculty members, postdoctoral researchers, students, and guests from industry and other laboratories who participated in LLNL's computational mission under the auspices of the ISCR during FY 2005.

  7. Basic Scientific Subroutines, Volume II.

    ERIC Educational Resources Information Center

    Ruckdeschel, F. R.

    This book, second in a series dealing with scientific programing in the BASIC language, provides students, engineers, and scientists with a documented library of subroutines for scientific applications. Subjects of the eight chapters include: (1) least-squares approximation of functions and smoothing of data; (2) approximating functions by series…

  8. The Benefits of Scientific Modeling

    ERIC Educational Resources Information Center

    Kenyon, Lisa; Schwarz, Christina; Hug, Barbara

    2008-01-01

    When students are engaged in scientific modeling, they are able to notice patterns and develop and revise representations that become useful models to predict and explain--making their own scientific knowledge stronger, helping them to think critically, and helping them know more about the nature of science. To illustrate, this article describes a…

  9. The Scientific Revolution: Paradigm Lost?

    ERIC Educational Resources Information Center

    Hatch, Robert A.

    1989-01-01

    Traces the historiography of the scientific revolution through a bibliographic essay. Examines trends in recent scholarly publications in an effort to identify new areas of research. Maintains that the study of the scientific revolution is problematic and cannot be reduced to simple analysis. (RW)

  10. Scientific and Technical Document Database

    National Institute of Standards and Technology Data Gateway

    NIST Scientific and Technical Document Database (PC database for purchase)   The images in NIST Special Database 20 contain a very rich set of graphic elements from scientific and technical documents, such as graphs, tables, equations, two column text, maps, pictures, footnotes, annotations, and arrays of such elements.

  11. The Scientific Response to Creationism.

    ERIC Educational Resources Information Center

    Cracraft, Joel

    1982-01-01

    Examines proposition that creationism is legitimate science, including philosophical basis of that claim and methods used to discredit contemporary scientific thought. Discusses creationist's arguments against scientific findings related to second law of thermodynamics, improbability of evolution, earth's age, geological record, fossil transitions…

  12. Who Is Scientifically Literate, Anyway?

    ERIC Educational Resources Information Center

    Hinman, Richard L.

    1998-01-01

    Recently, the National Academy of Sciences promulgated national standards for science education and defined scientific literacy. Literates should be able to describe, explain, and predict natural phenomena; understand popular-press articles on science; and evaluate the quality of scientific information, based on source and method. A fictional…

  13. Scientific Jargon, Good and Bad

    ERIC Educational Resources Information Center

    Hirst, Russel

    2003-01-01

    Scientific and technical jargon--specialized vocabulary, usually Latinate--plays a vital role in scientific and technical communication. But its proper use continues to be a point of discussion because of our concern with audience adaptation, rhetorical exigence, rhetorical purpose, and ethics. We've focused on teaching students--and on convincing…

  14. Scientific Research: Commodities or Commons?

    ERIC Educational Resources Information Center

    Vermeir, Koen

    2013-01-01

    Truth is for sale today, some critics claim. The increased commodification of science corrupts it, scientific fraud is rampant and the age-old trust in science is shattered. This cynical view, although gaining in prominence, does not explain very well the surprising motivation and integrity that is still central to the scientific life. Although…

  15. Scientific Research: How Many Paradigms?

    ERIC Educational Resources Information Center

    Strawn, George O.

    2012-01-01

    As Yogi Berra said, "Predictions are hard, especially about the future." In this article, the author offers a few forward-looking observations about the emerging impact of information technology on scientific research. Scientific research refers to a particular method for acquiring knowledge about natural phenomena. This method has two dimensions:…

  16. Advancing Scientific Research in Education

    ERIC Educational Resources Information Center

    Towne, Lisa, Ed.; Wise, Lauress L., Ed.; Winters, Tina M., Ed.

    2005-01-01

    The title of this report reveals its purpose precisely: to spur actions that will advance scientific research in education. The recommendations for accomplishing this goal, detailed in this report, build on the National Research Council (NRC) report "Scientific Research in Education" (National Research Council, 2002). That report offers an…

  17. Hazards Control Department annual technology review, 1987

    SciTech Connect

    Griffith, R.V.; Anderson, K.J.

    1988-07-01

    This document describes some of the research performed in the LLNL Hazards Control Department from October 1986 to September 1987. The sections in the Annual report cover scientific concerns in the areas of Health Physics, Industrial Hygiene, Industrial Safety, Aerosol Science, Resource Management, Dosimetry and Radiation Physics, Criticality Safety, and Fire Science. For a broader overview of the types of work performed in the Hazards Control Department, we have also compiled a selection of abstracts of recent publications by Hazards Control employees. Individual reports are processed separately for the data base.

  18. 2010 Annual Report

    SciTech Connect

    2010-01-01

    This annual report includes: an overview of Western; approaches for future hydropower and transmission service; major achievements in FY 2010; FY 2010 customer Integrated Resource Planning, or IRP, survey; and financial data.

  19. Scientific Autonomy and Public Oversight

    PubMed Central

    Resnik, David B.

    2009-01-01

    When scientific research collides with social values, science’s right to self-governance becomes an issue of paramount concern. In this article, I develop an account of scientific autonomy within a framework of public oversight. I argue that scientific autonomy is justified because it promotes the progress of science, which benefits society, but that restrictions on autonomy can also be justified to prevent harm to people, society, or the environment, and to encourage beneficial research. I also distinguish between different ways of limiting scientific autonomy, and I argue that government involvement in scientific decision-making should usually occur through policies that control the process of science, rather than policies that control the content of science. PMID:19777124

  20. PHIGS PLUS for scientific graphics

    SciTech Connect

    Crawfis, R.A.

    1991-01-14

    This paper gives a brief overview of the use of computer graphics standards in the scientific community. It particularly details how how PHIGS PLUS meets the needs of users at the Lawrence Livermore National Laboratory. Although standards for computer graphics have improved substantially over the past decade, their acceptance in the scientific community has been slow. As the use and diversity of computers has increased, the scientific graphics libraries have not been able to keep pace with the additional capabilities these new machines offer. Therefore, several organizations have or are now working on converting their scientific libraries to reset upon a portable standard. This paper will address why is transition has been so slow and offer suggestions for future standards work to enhance scientific visualization. This work was performed under the auspices of the US Department of Energy by Lawrence Livermore National Laboratory under contract No. W-7405-Eng-48.

  1. Natural gas annual 1994

    SciTech Connect

    1995-11-17

    The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. The 1994 data are presented in a sequence that follows natural gas (including supplemental supplies) from its production to its end use. This is followed by tables summarizing natural gas supply and disposition from 1990 to 1994 for each Census Division and each State. Annual historical data are shown at the national level.

  2. Natural gas annual 1995

    SciTech Connect

    1996-11-01

    The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. The 1995 data are presented in a sequence that follows natural gas (including supplemental supplies) from its production to its end use. This is followed by tables summarizing natural gas supply and disposition from 1991 to 1995 for each Census Division and each State. Annual historical data are shown at the national level.

  3. Addressing submarine geohazards through scientific drilling

    NASA Astrophysics Data System (ADS)

    Camerlenghi, A.

    2009-04-01

    multi-platform drilling of the Nankai seismogenic zone. Scientific initiatives are flourishing to drive IODP towards the study of submarine geohazards. In the last three years international workshops, were held to address the topic: ESF-ECORD sponsored a Magellan Workshop focussed on submarine landslides (Barcelona, Spain, 2006); IODP sponsored a world-wide Geohazard Workshop (Portland, Oregon, 2007); ESF-ECORD sponsored another Magellan Workshop focussed on Mediterranean submarine geohazards (Luleå, Sweden, 2008). In addition, following the ECORD-Net Conference on the Deep Sea Frontier (Naples, Italy, 2006), the history, monitoring and prediction of geohazards was identified as one of the 6 major areas for a European science plan to integrate Ocean Drilling, Ocean Margin, and Seabed research. More than 200 scientists and private companies representatives have been mobilized world-wide to attend these meetings, from where it emerged that Ocean Drilling will play a key role in the future to answer the following basic open questions on submarine geohazards: - What is the frequency, magnitude, and distribution of geohazard events? - Do precursory phenomena exist and can they be recognized? - What are the physical and mechanical properties of materials prone to failure? - What are the roles of preconditioning vs. triggering in rapid seafloor deformation? - Can the tsunamigenic potential of past and future events be assessed? Within the global-ocean geohazards, worth of note is the attention given in this preparatory phase to submarine geohazards in the Mediterranean basin, a miniature ocean often called a "natural laboratory" because of the diversity of geological environments it contains. The coastline is very densely-populated, totalling 160 million inhabitants sharing 46,000 km of coastline. The Mediterranean is the World's leading holiday destination, receiving an average of 135 million visitors annually. Submarine landslides, volcanic flank collapses, volcanic island

  4. Lessons Over a Decade of Writing About Scientific Data

    NASA Astrophysics Data System (ADS)

    Beitler, J.; Collins, S. R.; Naranjo, L.

    2006-12-01

    For eleven years, the NASA Distributed Active Archive Centers (DAACs) have sponsored writing about research and applications using NASA remote sensing data. The publication, NASA: Supporting Earth System Science, is premised on stimulating scientific curiosity and leading a broad audience carefully into the challenging puzzles that researchers address with the help of remote-sensing data. The National Snow and Ice Data Center, one of the NASA DAACs, has handled the challenge of telling these stories across multiple science disciplines, researching and writing ten to twelve articles each year. Our approach centers on quality science. We preserve its complexity, and attract and stimulate audience interest by placing scientific endeavor at center stage. We propose to share our experiences, successes, and strategies with others who are interested in telling stories that highlight the essential nature of data in the scientific enterprise. We have learned how to write engagingly about abstract, long-term research projects involving a lot of math and physics, in ways that appeal to both scientific and lay readers. We will also talk about the skills and resources that we consider necessary to write informative data stories. We welcome leads on scientific research topics that use NASA remote sensing data. Talk to us at the conference, or write us at nasadaacs@nsidc.org. View our eleventh annual publication as well as past stories online at http://nasadaacs.eos.nasa.gov/articles/index.html, or stop by the NASA booth to pick up a color copy.

  5. ISCR annual report FY 1998

    SciTech Connect

    Fitzgerald, John M.

    1999-05-03

    Advances in scientific computing research have never been more vital to the core missions of Lawrence Livermore National Laboratory than they are today. These advances are evolving so rapidly, and over such a broad front of computational science, that to remain on the leading edge, the Laboratory must collaborate with many academic centers of excellence. In FY 1998, ISCR dramatically expanded its interactions with academia through collaborations, visiting faculty, guests and a seminar series. The pages of this annual report summarize the activities of the 63 faculty members and 34 students who participated in ISCR collaborative activities during FY 1998. The 1998 ISCR call for proposals issued by the University Collaborative Research Program (UCRP) resulted in eight awards made by the University of California Office of the President to research teams at UC San Diego, UC Davis, UC Los Angeles, and UC Berkeley. These projects are noted. ISCR is now part of the Laboratory's Center for Applied Scientific Computing (CASC). Many CASC scientists participate actively in ISCR University collaborations, as noted. The eight collaborations shown represent innovative research efforts supported by ISCR in FY 1998. Abstracts discussing each of these collaborations begin on page 79. The Accelerated Strategic Computing Initiative (ASCI) established Academic Strategic Alliances Program (ASAP) centers located at: Stanford University; California Institute of Technology; University of Chicago; University of Utah, Salt Lake; and University of Illinois, Urbana-Champaign. The ASCI Alliances strategy was established to enhance overall ASCI goals by establishing technical interactions between the Department of Energy, Defense Programs laboratories (Lawrence Livermore, Los Alamos, and Sandia National Laboratories), and leading-edge research-and-development universities in the United States. ISCR has partnered with the LLNL ASCI Program Office to facilitate these collaborations. In FY 1998

  6. Uncloaking the Scientific Process

    NASA Astrophysics Data System (ADS)

    Leitzell, K.; Meier, W.

    2009-12-01

    Since April 2008, NSIDC has offered daily updates of sea ice data on our Arctic Sea Ice News & Analysis Web page (http://nsidc.org/arcticseaicenews). The images provide near-real-time data to the general public and policy makers, accompanied by monthly or more frequent analysis updates. In February 2009, a crucial channel of the Special Sensor Microwave/Imager (SSM/I) sensor on the Defense Meteorological Satellite Program (DMSP) F15 satellite, from which NSIDC was obtaining near-real-time Arctic sea ice data, suddenly failed. The daily image, which is automatically updated, showed a sudden drop in ice extent of over 50,000 square kilometers. Even after taking the images down, skeptical blogs jumped on the event, posting headlines such as “Errors in publicly presented data - Worth blogging about?” and “NSIDC pulls the plug on sea ice data.” In fact, NSIDC data managers and scientists were well aware that the F15 satellite sensor would eventually fail. NSIDC switched to a previously used back-up sensor, F13, and work to transition to a newer sensor on the F17 satellite had been underway for several weeks. While the deluge of questions from readers and bloggers were frustrating to NSIDC communications staff and scientists, they also presented a chance to give readers a window into the scientific process, and specifically into the collection of satellite data. We decided to publish a clear account of the process used to transition between sensors, as well as a basic explanation of the satellites used to measure sea ice data. While most scientists are familiar with the limitations of near-real-time data, the concept is unfamiliar to many in the general public. The Web page includes links to information on near-real-time data, including notes that images sometimes contain missing or erroneous data, and that delays can occur. However, to a skeptical person, the words that scientists use to describe the processing of final data, including “adjustment,”

  7. The spacelab scientific missions: A comprehensive bibliography of scientific publications

    NASA Technical Reports Server (NTRS)

    Torr, Marsha (Compiler)

    1995-01-01

    November 1993 represented the 10-year anniversary of the flight of Spacelab 1 mission, with the first precursor mission (OSTA-1) being launched 2 years earlier. Since that time, a total of 27 Shuttle missions has been flown, using the Spacelab system as a facility for conducting scientific research in space. The missions flown to date have allowed a total of approximately 500 Principle Investigator class investigations to be conducted in orbit. These investigations have constituted major scientific efforts in astronomy/astrophysics, atmospheric science, Earth observation, life sciences, microgravity science, and space plasma physics. An initial survey of the scientific products gleaned from Spacelab missions already flown was sent to the Principle Investigators. In that survey, information was gathered from the investigators on the scientific highlights of their investigations and statistical measurements of overall success -- such as papers published. This document is a compilation of the papers that have been published to date in referred literature.

  8. The 68th American Epilepsy Society Annual Meeting Seattle (WA), USA, December 5-9, 2014

    PubMed Central

    Al-Baradie, Raidah S.

    2015-01-01

    The American Epilepsy Society’s Annual Meeting is the premiere meeting for epilepsy and other seizure disorders. The Annual Meeting is an international forum for the exchange of current findings in epilepsy research. Information is communicated and disseminated through symposia, lectures, scientific exhibitions, poster, and platform presentations. The Annual Meeting attracts attendees from all over the world and provides educational and networking opportunities for the academic and practicing neurologist, epileptologist, neurophysiologist, neuroscientist, neurosurgeon, internist, pediatrician, pharmacist, nurse, social worker, and other professionals. In 2014, the American Epilepsy Society Annual Meeting was held on 5-9 December 2014 in Seattle (WA), USA. The following syllabus provides highlights from this meeting.

  9. Scientific Visualization, Seeing the Unseeable

    ScienceCinema

    LBNL

    2009-09-01

    June 24, 2008 Berkeley Lab lecture: Scientific visualization transforms abstract data into readily comprehensible images, provide a vehicle for "seeing the unseeable," and play a central role in bo... June 24, 2008 Berkeley Lab lecture: Scientific visualization transforms abstract data into readily comprehensible images, provide a vehicle for "seeing the unseeable," and play a central role in both experimental and computational sciences. Wes Bethel, who heads the Scientific Visualization Group in the Computational Research Division, presents an overview of visualization and computer graphics, current research challenges, and future directions for the field.

  10. Scientific Visualization, Seeing the Unseeable

    SciTech Connect

    LBNL

    2008-07-08

    June 24, 2008 Berkeley Lab lecture: Scientific visualization transforms abstract data into readily comprehensible images, provide a vehicle for "seeing the unseeable," and play a central role in bo... June 24, 2008 Berkeley Lab lecture: Scientific visualization transforms abstract data into readily comprehensible images, provide a vehicle for "seeing the unseeable," and play a central role in both experimental and computational sciences. Wes Bethel, who heads the Scientific Visualization Group in the Computational Research Division, presents an overview of visualization and computer graphics, current research challenges, and future directions for the field.

  11. Scientific Services on the Cloud

    NASA Astrophysics Data System (ADS)

    Chapman, David; Joshi, Karuna P.; Yesha, Yelena; Halem, Milt; Yesha, Yaacov; Nguyen, Phuong

    Scientific Computing was one of the first every applications for parallel and distributed computation. To this date, scientific applications remain some of the most compute intensive, and have inspired creation of petaflop compute infrastructure such as the Oak Ridge Jaguar and Los Alamos RoadRunner. Large dedicated hardware infrastructure has become both a blessing and a curse to the scientific community. Scientists are interested in cloud computing for much the same reason as businesses and other professionals. The hardware is provided, maintained, and administrated by a third party. Software abstraction and virtualization provide reliability, and fault tolerance. Graduated fees allow for multi-scale prototyping and execution. Cloud computing resources are only a few clicks away, and by far the easiest high performance distributed platform to gain access to. There may still be dedicated infrastructure for ultra-scale science, but the cloud can easily play a major part of the scientific computing initiative.

  12. Cultural complexities and scientific development.

    PubMed

    Branco, Angela Uchoa

    2007-03-01

    Methodological issues in psychology consist of a key aspect for the scientific development of the discipline. In this paper I elaborate on the reasons why I partially agree with Toomela's ideas, and why I also disagree with some of his arguments. The convergence refers to the need for a radical change concerning the widespread use of methodologies that has been typical of mainstream psychology, which still flavors too positivist and pseudo-quantitative, overlooking the central relevance of theory for scientific development. The divergence resides in Toomela's insistence to oppose what he designates as "the North American" to "the German-Austrian" scientific thinking: from my perspective, the misuse of cultural categories can only lead to misguided and unconstructive dichotomies that entails a naive concept of culture, and do not contribute to scientific development. From a contemporary systemic approach, complex issues deserve more sophisticated analysis. PMID:17992868

  13. EPA scientific integrity policy draft

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-08-01

    The U.S. Environmental Protection Agency (EPA) issued its draft scientific integrity policy on 5 August. The draft policy addresses scientific ethical standards, communications with the public, the use of advisory committees and peer review, and professional development. The draft policy was developed by an ad hoc group of EPA senior staff and scientists in response to a December 2010 memorandum on scientific integrity from the White House Office of Science and Technology Policy. The agency is accepting public comments on the draft through 6 September; comments should be sent to osa.staff@epa.gov. For more information, see http://www.epa.gov/stpc/pdfs/draft-scientific-integrity-policy-aug2011.pdf.

  14. Cholera and the Scientific Method.

    ERIC Educational Resources Information Center

    Cronin, Jim

    1993-01-01

    Describes an approach to teaching the scientific method where an outbreak of cholera within the school is simulated. Students act like epidemiologists in an attempt to track down the source of the contamination. (PR)

  15. SRNL LDRD ANNUAL REPORT 2008

    SciTech Connect

    French, T

    2008-12-29

    The Laboratory Director is pleased to have the opportunity to present the 2008 Laboratory Directed Research and Development (LDRD) annual report. This is my first opportunity to do so, and only the second such report that has been issued. As will be obvious, SRNL has built upon the excellent start that was made with the LDRD program last year, and researchers have broken new ground in some important areas. In reviewing the output of this program this year, it is clear that the researchers implemented their ideas with creativity, skill and enthusiasm. It is gratifying to see this level of participation, because the LDRD program remains a key part of meeting SRNL's and DOE's strategic goals, and helps lay a solid scientific foundation for SRNL as the premier applied science laboratory. I also believe that the LDRD program's results this year have demonstrated SRNL's value as the EM Corporate Laboratory, having advanced knowledge in a spectrum of areas, including reduction of the technical risks of cleanup, separations science, packaging and transportation of nuclear materials, and many others. The research in support of Energy Security and National and Homeland Security has been no less notable. SRNL' s researchers have shown again that the nascent LDRD program is a sound investment for DOE that will pay off handsomely for the nation as time goes on.

  16. Scientific Research: Commodities or Commons?

    NASA Astrophysics Data System (ADS)

    Vermeir, Koen

    2013-10-01

    Truth is for sale today, some critics claim. The increased commodification of science corrupts it, scientific fraud is rampant and the age-old trust in science is shattered. This cynical view, although gaining in prominence, does not explain very well the surprising motivation and integrity that is still central to the scientific life. Although scientific knowledge becomes more and more treated as a commodity or as a product that is for sale, a central part of academic scientific practice is still organized according to different principles. In this paper, I critically analyze alternative models for understanding the organization of knowledge, such as the idea of the scientific commons and the gift economy of science. After weighing the diverse positive and negative aspects of free market economies of science and gift economies of science, a commons structured as a gift economy seems best suited to preserve and take advantage of the specific character of scientific knowledge. Furthermore, commons and gift economies promote the rich social texture that is important for supporting central norms of science. Some of these basic norms might break down if the gift character of science is lost. To conclude, I consider the possibility and desirability of hybrid economies of academic science, which combine aspects of gift economies and free market economies. The aim of this paper is to gain a better understanding of these deeper structural challenges faced by science policy. Such theoretical reflections should eventually assist us in formulating new policy guidelines.

  17. The (Surplus) Value of Scientific Communication.

    ERIC Educational Resources Information Center

    Frohlich, Gerhard

    1996-01-01

    Discusses research on scientific communication. Topics include theory-less and formal technical/natural scientific models of scientific communication; social-scientific, power-sensitive models; the sociology of scientific communication; sciences as fields of competition; fraud and deception; potential surplus value across subject information…

  18. Second Annual David Derse Memorial Lecture and Award | Poster

    Cancer.gov

    By Anne Arthur, Guest Writer The Second Annual David Derse Memorial Lecture and Award presentation was held on November 12, 2013, at the NCI at Frederick Conference Center to honor David Derse’s outstanding research accomplishments and to stimulate the exchange of innovative ideas that Derse was well known for promoting throughout his scientific career. The Annual David Derse Memorial Lecture and Award is sponsored by the HIV Drug Resistance Program, with support from Hye Kyung Chung-Derse, Ph.D., the National Cancer Institute (NCI), the Foundation for the National Institutes of Health (NIH), and colleagues and friends of Derse who contributed to the memorial fund in his honor.

  19. Natural Areas--Needs and Opportunities, 1970 Symposium Proceedings, Northwest Scientific Association.

    ERIC Educational Resources Information Center

    Dittrich, William J., Ed.; Trappe, James M., Ed.

    Proceedings of a symposium held at the Northwest Scientific Association Forty-Third Annual Meeting, Salem, Oregon, March, 1970, are presented. The symposium indicated that mutual understanding by educators, scientists, land managers, and politicians must be developed on the definition of naturalness, present and future use and management of…

  20. ESO and Chile: 10 Years of Productive Scientific Collaboration

    NASA Astrophysics Data System (ADS)

    2006-06-01

    ESO and the Government of Chile launched today the book "10 Years Exploring the Universe", written by the beneficiaries of the ESO-Chile Joint Committee. This annual fund provides grants for individual Chilean scientists, research infrastructures, scientific congresses, workshops for science teachers and astronomy outreach programmes for the public. In a ceremony held in Santiago on 19 June 2006, the European Organisation for Astronomical Research in the Southern Hemisphere (ESO) and the Chilean Ministry of Foreign Affairs marked the 10th Anniversary of the Supplementary Agreement, which granted to Chilean astronomers up to 10 percent of the total observing time on ESO telescopes. This agreement also established an annual fund for the development of astronomy, managed by the so-called "ESO-Chile Joint Committee". ESO PR Photo 21/06 ESO PR Photo 21/06 Ten Years ESO-Chile Agreement Ceremony The celebration event was hosted by ESO Director General, Dr. Catherine Cesarsky, and the Director of Special Policy for the Chilean Ministry of Foreign Affairs, Ambassador Luis Winter. "ESO's commitment is, and always will be, to promote astronomy and scientific knowledge in the country hosting our observatories", said ESO Director General, Dr. Catherine Cesarsky. "We hope Chile and Europe will continue with great achievements in this fascinating joint adventure, the exploration of the universe." On behalf of the Government of Chile, Ambassador Luis Winter outlined the historical importance of the Supplementary Agreement, ratified by the Chilean Congress in 1996. "Such is the magnitude of ESO-Chile Joint Committee that, only in 2005, this annual fund represented 8 percent of all financing sources for Chilean astronomy, including those from Government and universities", Ambassador Winter said. The ESO Representative and Head of Science in Chile, Dr. Felix Mirabel, and the appointed Chilean astronomer for the ESO-Chile Joint Committee, Dr. Leonardo Bronfman, also took part in the

  1. International energy annual 1996

    SciTech Connect

    1998-02-01

    The International Energy Annual presents an overview of key international energy trends for production, consumption, imports, and exports of primary energy commodities in over 220 countries, dependencies, and areas of special sovereignty. Also included are population and gross domestic product data, as well as prices for crude oil and petroleum products in selected countries. Renewable energy reported in the International Energy Annual includes hydroelectric power, geothermal, solar, and wind electric power, biofuels energy for the US, and biofuels electric power for Brazil. New in the 1996 edition are estimates of carbon dioxide emissions from the consumption of petroleum and coal, and the consumption and flaring of natural gas. 72 tabs.

  2. Annual Energy Outlook

    EIA Publications

    2015-01-01

    The projections in the U.S. Energy Information Administration's (EIA's) Annual Energy Outlook 2015 (AEO2015) focus on the factors that shape the U.S. energy system over the long term. For the first time, the Annual Energy Outlook (AEO) is presented as a shorter edition under a newly adopted two-year release cycle. With this approach, full editions and shorter editions of the AEO will be produced in alternating years. This approach will allow EIA to focus more resources on rapidly changing energy markets both in the United States and internationally, and to consider how they might evolve over the next few years.

  3. CPTAC Scientific Symposium - Office of Cancer Clinical Proteomics Research

    Cancer.gov

    On behalf of the National Cancer Institute and the Office of Cancer Clinical Proteomics Research, you are invited to the First Annual CPTAC Scientific Symposium on Wednesday, November 13, 2013. The purpose of this symposium, which consists of plenary and poster sessions, is for investigators from CPTAC community and beyond to share and discuss novel biological discoveries, analytical methods, and translational approaches using CPTAC data. All scientists who use, or wish to use CPTAC data are welcome to participate at this free event. The symposium will be held at the Natcher Conference Facility on the main campus of the National Institutes of Health in Bethesda, Maryland.

  4. Commentary: Flawed scientific-evidence standards delay diesel regulations.

    PubMed

    Pusateri, Antoinette; Shrader-Frechette, Kristin

    2015-01-01

    Of 188 government-monitored air toxics, diesel particulate matter (DPM) causes seven times more cancer than all the other 187 air toxics combined, including benzene, lead, and mercury. Yet, DPM is the only air toxic not regulated more stringently under the Clean Air Act, as a hazardous air pollutant (HAP). One reason is that regulators use flawed standards of scientific evidence. The article argues (1) that DPM meets all six specified evidentiary criteria, any one of which is sufficient for HAP regulation and (2) that regulators' standards of evidence for denying HAP status to DPM (no DPM unit-risk estimate, inadequate dose-response data, alleged weak mechanistic data) err logically and scientifically, set the evidence bar too high, delay regulation, and allow 21,000 avoidable DPM deaths annually in the U.S. PMID:25635848

  5. Laboratory Directed Research and Development FY-10 Annual Report

    SciTech Connect

    Dena Tomchak

    2011-03-01

    The FY 2010 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL -- it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

  6. Addressing submarine geohazards through scientific drilling

    NASA Astrophysics Data System (ADS)

    Camerlenghi, A.

    2009-04-01

    multi-platform drilling of the Nankai seismogenic zone. Scientific initiatives are flourishing to drive IODP towards the study of submarine geohazards. In the last three years international workshops, were held to address the topic: ESF-ECORD sponsored a Magellan Workshop focussed on submarine landslides (Barcelona, Spain, 2006); IODP sponsored a world-wide Geohazard Workshop (Portland, Oregon, 2007); ESF-ECORD sponsored another Magellan Workshop focussed on Mediterranean submarine geohazards (Luleå, Sweden, 2008). In addition, following the ECORD-Net Conference on the Deep Sea Frontier (Naples, Italy, 2006), the history, monitoring and prediction of geohazards was identified as one of the 6 major areas for a European science plan to integrate Ocean Drilling, Ocean Margin, and Seabed research. More than 200 scientists and private companies representatives have been mobilized world-wide to attend these meetings, from where it emerged that Ocean Drilling will play a key role in the future to answer the following basic open questions on submarine geohazards: - What is the frequency, magnitude, and distribution of geohazard events? - Do precursory phenomena exist and can they be recognized? - What are the physical and mechanical properties of materials prone to failure? - What are the roles of preconditioning vs. triggering in rapid seafloor deformation? - Can the tsunamigenic potential of past and future events be assessed? Within the global-ocean geohazards, worth of note is the attention given in this preparatory phase to submarine geohazards in the Mediterranean basin, a miniature ocean often called a "natural laboratory" because of the diversity of geological environments it contains. The coastline is very densely-populated, totalling 160 million inhabitants sharing 46,000 km of coastline. The Mediterranean is the World's leading holiday destination, receiving an average of 135 million visitors annually. Submarine landslides, volcanic flank collapses, volcanic island

  7. NUFFIC Annual Report, 1977.

    ERIC Educational Resources Information Center

    Netherlands Universities Foundation for International Co-operation, The Hague.

    The 1977 annual report of the Netherlands Universities Foundation for International Cooperation (NUFFIC) considers the following topics: major developments in work and policy; relationships NUFFIC has with other organizations; University Development Cooperation; developments in international education; the functioning of the Consultative Structure…

  8. UNICEF Annual Report 1983.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    In introducing this annual report, the executive director of UNICEF delineates the four techniques for primary health care and basic services reported in the publication "State of the World's Children, 1982-1983." The ensuing review of UNICEF's activities illustrates highlights of the year's program cooperation, including trends and key events, by…

  9. International Energy Annual, 1992

    SciTech Connect

    Not Available

    1994-01-14

    This report is prepared annually and presents the latest information and trends on world energy production and consumption for petroleum, natural gas, coal, and electricity. Trade and reserves are shown for petroleum, natural gas, and coal. Prices are included for selected petroleum products. Production and consumption data are reported in standard units as well as British thermal units (Btu) and joules.

  10. 2010 AAUW Annual Report

    ERIC Educational Resources Information Center

    American Association of University Women, 2010

    2010-01-01

    This report highlights some of the outstanding accomplishments of AAUW (American Association of University Women) for fiscal year 2010. This year's annual report also features stories of remarkable women who are leading the charge to break through barriers and ensure that all women have a fair chance. Sharon is working to reduce the pay gap…

  11. Magnetic Resonance Annual, 1985

    SciTech Connect

    Kressel, H.Y.

    1985-01-01

    The inaugural volume of Magnetic Resonance Annual includes reviews of MRI of the posterior fossa, cerebral neoplasms, and the cardiovascular and genitourinary systems. A chapter on contrast materials outlines the mechanisms of paramagnetic contrast enhancement and highlights several promising contrast agents.

  12. Ultrasound Annual, 1984

    SciTech Connect

    Sanders, R.C.; Hill, M.C.

    1984-01-01

    The 1984 edition of Ultrasound Annual explores new applications of ultrasound in speech and swallowing and offers guidelines on the use of ultrasound and nuclear medicine in thyroid and biliary tract disease. Other areas covered include Doppler sonography of the abdomen, intraoperative abdominal ultrasound, sonography of the placenta, ultrasound of the neonatal head and abdomen, and sonographic echo patterns created by fat.

  13. Annual Research Briefs - 1996

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This report contains the 1996 annual progress reports of the research fellows and students supported by the Center for Turbulence Research. Last year, CTR hosted twelve resident Postdoctoral Fellows, three Research Associates, four Senior Research Fellows, and supported one doctoral student and ten short term visitors.

  14. UNICEF Annual Report, 1995.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, N.Y.

    This annual report for the United Nations Children's Fund (UNICEF) details the programs and services provided by this organization in 1994. Following an overview of the year and a remembrance of former UNICEF Executive Director James P. Grant, the report describes developments in seven world regions and in specific emergency countries. The report…

  15. UNICEF Annual Report, 1993.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This annual report for the United Nations Children's Fund (UNICEF) details the programs and services provided by this organization in 1992-93. Following an introduction by UNICEF's executive director, the report briefly reviews UNICEF activities for 1992, then describes specific projects in the following areas: (1) child survival and development;…

  16. UNICEF Annual Report, 1994.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This annual report for the United Nations Children's Fund (UNICEF) describes the programs and services provided by this organization in 1993. Following an introduction by UNICEF's executive director, the report reviews regional developments in Sub-Saharan Africa, the Middle East and North Africa, East Asia and the Pacific, South Asia, Latin…

  17. Annual Conference Abstracts

    ERIC Educational Resources Information Center

    Engineering Education, 1976

    1976-01-01

    Presents the abstracts of 158 papers presented at the American Society for Engineering Education's annual conference at Knoxville, Tennessee, June 14-17, 1976. Included are engineering topics covering education, aerospace, agriculture, biomedicine, chemistry, computers, electricity, acoustics, environment, mechanics, and women. (SL)

  18. Carolinas Communication Annual, 1999.

    ERIC Educational Resources Information Center

    McLennan, David B.

    1999-01-01

    This 1999 issue of the "Carolinas Communication Annual" contains the following articles: "The Unmade Analogy: Alcohol and Abortion" (Richard W. Leeman); "Say, You Want a Revolution" (Roy Schwartzman and Constance Y. Green); "Exploring the Relationship between Perceived Narrativity and Persuasiveness" (Richard Olsen and Rodney A. Reynolds); "In…

  19. Annual Income Tax Guide.

    ERIC Educational Resources Information Center

    Exceptional Parent, 1988

    1988-01-01

    The annual income tax guide is designed to familiarize parents with the tax laws that specifically affect persons with disabilities and their families. Summarized are the changes for 1988 as well as guidelines for itemized deductions, tax credits, and the deduction for dependents. (DB)

  20. UNICEF Annual Report. 1984.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    This annual report reviews the work UNICEF has been doing to help transform the "Child Survival Revolution" from a dream into a reality. Discussion focuses primarily on child health and nutrition and other basic services for children. Throughout, the review is supplemented with profiles of program initiatives made to improve the conditions of the…

  1. ASE Annual Conference 2010

    ERIC Educational Resources Information Center

    McCune, Roger

    2010-01-01

    In this article, the author describes the ASE Annual Conference 2010 which was held at Nottingham after a gap of 22 years. As always, the main conference was preceded by International Day, an important event for science educators from across the world. There were two strands to the programme: (1) "What works for me?"--sharing new ideas and tried…

  2. Annual Income Tax Guide.

    ERIC Educational Resources Information Center

    Keener, Sandra C.

    1992-01-01

    This annual guide to income tax for parents of children with disabilities covers organizing records; avoiding audits; deducting medical expenses; and considering the impact of recent changes in medical expenses, Social Security numbers for children, child care, earned income credit, and deduction for dependents. (DB)

  3. Annual Conference Abstracts

    ERIC Educational Resources Information Center

    Journal of Engineering Education, 1972

    1972-01-01

    Includes abstracts of papers presented at the 80th Annual Conference of the American Society for Engineering Education. The broad areas include aerospace, affiliate and associate member council, agricultural engineering, biomedical engineering, continuing engineering studies, chemical engineering, civil engineering, computers, cooperative…

  4. Annual Coal Distribution

    EIA Publications

    2016-01-01

    The Annual Coal Distribution Report (ACDR) provides detailed information on domestic coal distribution by origin state, destination state, consumer category, and method of transportation. Also provided is a summary of foreign coal distribution by coal-producing state. All data for the report year are final and this report supersedes all data in the quarterly distribution reports.

  5. UNICEF Annual Report, 1996.

    ERIC Educational Resources Information Center

    United Nations Children's Fund, New York, NY.

    At this time, the United Nations Children Fund (UNICEF) is commemorating its 50th anniversary, under the slogan "children first." This annual UNICEF report reviews the organization's activities during 1995. An introduction by the executive director states that the report will give readers a sense of what UNICEF is doing with partners to rise to…

  6. Uranium industry annual 1998

    SciTech Connect

    1999-04-22

    The Uranium Industry Annual 1998 (UIA 1998) provides current statistical data on the US uranium industry`s activities relating to uranium raw materials and uranium marketing. It contains data for the period 1989 through 2008 as collected on the Form EIA-858, ``Uranium Industry Annual Survey.`` Data provides a comprehensive statistical characterization of the industry`s activities for the survey year and also include some information about industry`s plans and commitments for the near-term future. Data on uranium raw materials activities for 1989 through 1998, including exploration activities and expenditures, EIA-estimated reserves, mine production of uranium, production of uranium concentrate, and industry employment, are presented in Chapter 1. Data on uranium marketing activities for 1994 through 2008, including purchases of uranium and enrichment services, enrichment feed deliveries, uranium fuel assemblies, filled and unfilled market requirements, and uranium inventories, are shown in Chapter 2. The methodology used in the 1998 survey, including data edit and analysis, is described in Appendix A. The methodologies for estimation of resources and reserves are described in Appendix B. A list of respondents to the ``Uranium Industry Annual Survey`` is provided in Appendix C. The Form EIA-858 ``Uranium Industry Annual Survey`` is shown in Appendix D. For the readers convenience, metric versions of selected tables from Chapters 1 and 2 are presented in Appendix E along with the standard conversion factors used. A glossary of technical terms is at the end of the report. 24 figs., 56 tabs.

  7. Parallel processing for scientific computations

    NASA Technical Reports Server (NTRS)

    Alkhatib, Hasan S.

    1995-01-01

    The scope of this project dealt with the investigation of the requirements to support distributed computing of scientific computations over a cluster of cooperative workstations. Various experiments on computations for the solution of simultaneous linear equations were performed in the early phase of the project to gain experience in the general nature and requirements of scientific applications. A specification of a distributed integrated computing environment, DICE, based on a distributed shared memory communication paradigm has been developed and evaluated. The distributed shared memory model facilitates porting existing parallel algorithms that have been designed for shared memory multiprocessor systems to the new environment. The potential of this new environment is to provide supercomputing capability through the utilization of the aggregate power of workstations cooperating in a cluster interconnected via a local area network. Workstations, generally, do not have the computing power to tackle complex scientific applications, making them primarily useful for visualization, data reduction, and filtering as far as complex scientific applications are concerned. There is a tremendous amount of computing power that is left unused in a network of workstations. Very often a workstation is simply sitting idle on a desk. A set of tools can be developed to take advantage of this potential computing power to create a platform suitable for large scientific computations. The integration of several workstations into a logical cluster of distributed, cooperative, computing stations presents an alternative to shared memory multiprocessor systems. In this project we designed and evaluated such a system.

  8. New Observational Technologies Scientific and Societal Impacts

    NASA Astrophysics Data System (ADS)

    Fabry, F.; Zawadzki, I.

    INTRODUCTION REMOTE SENSING OF THE ATMOSPHERE REMOTE SENSORS AND THEIR SCIENTIFIC IMPACTS Air Temperature and Moisture Clouds and Precipitation Wind Others Related Scientific Considerations SOCIETAL IMPACTS CONCLUSIONS REFERENCES

  9. Correction and Use of Biomedical Literature Affected by Scientific Misconduct

    PubMed Central

    Neale, Anne Victoria; Northrup, Justin; Dailey, Rhonda; Marks, Ellen; Abrams, Judith

    2009-01-01

    The purpose of this study was to identify and describe published research articles that were named in official findings of scientific misconduct and to investigate compliance with the administrative actions contained in these reports for corrections and retractions, as represented in PubMed. Between 1993 and 2001, 102 articles were named in either the NIH Guide for Grants and Contracts (“Findings of Scientific Misconduct”) or the U.S. Office of Research Integrity annual reports as needing retraction or correction. In 2002, 98 of the 102 articles were indexed in PubMed. Eighty-five of these 98 articles had indexed corrections: 47 were retracted; 26 had an erratum; 12 had a correction described in the “comment” field. Thirteen had no correction, but 10 were linked to the NIH Guide “Findings of Scientific Misconduct”, leaving only 3 articles with no indication of any sort of problem. As of May 2005, there were 5,393 citations to the 102 articles, with a median of 26 citations per article (range 0–592). Researchers should be alert to “Comments” linked to the NIH Guide as these are open access, and the “Findings of Scientific Misconduct’ reports are often more informative than the statements about the retraction or correction found in the journals. PMID:17703606

  10. The Effectiveness of Scientific Inquiry With/Without Integration of Scientific Reasoning

    ERIC Educational Resources Information Center

    Chen, Chun-Ting; She, Hsiao-Ching

    2015-01-01

    This study examines the difference in effectiveness between two scientific inquiry programs-one with an emphasis on scientific reasoning and one without a scientific reasoning component-on students' scientific concepts, scientific concept-dependent reasoning, and scientific inquiry. A mixed-method approach was used in which 115 grade 5…

  11. Advanced Aerobots for Scientific Exploration

    NASA Technical Reports Server (NTRS)

    Behar, Alberto; Raymond, Carol A.; Matthews, Janet B.; Nicaise, Fabien; Jones, Jack A.

    2010-01-01

    The Picosat and Uninhabited Aerial Vehicle Systems Engineering (PAUSE) project is developing balloon-borne instrumentation systems as aerobots for scientific exploration of remote planets and for diverse terrestrial purposes that can include scientific exploration, mapping, and military surveillance. The underlying concept of balloon-borne gondolas housing outer-space-qualified scientific instruments and associated data-processing and radio-communication equipment is not new. Instead, the novelty lies in numerous design details that, taken together, make a PAUSE aerobot smaller, less expensive, and less massive, relative to prior aerobots developed for similar purposes: Whereas the gondola (including the instrumentation system housed in it) of a typical prior aerobot has a mass of hundreds of kilograms, the mass of the gondola (with instrumentation system) of a PAUSE aerobot is a few kilograms.

  12. Scientific CCD technology at JPL

    NASA Technical Reports Server (NTRS)

    Janesick, J.; Collins, S. A.; Fossum, E. R.

    1991-01-01

    Charge-coupled devices (CCD's) were recognized for their potential as an imaging technology almost immediately following their conception in 1970. Twenty years later, they are firmly established as the technology of choice for visible imaging. While consumer applications of CCD's, especially the emerging home video camera market, dominated manufacturing activity, the scientific market for CCD imagers has become significant. Activity of the Jet Propulsion Laboratory and its industrial partners in the area of CCD imagers for space scientific instruments is described. Requirements for scientific imagers are significantly different from those needed for home video cameras, and are described. An imager for an instrument on the CRAF/Cassini mission is described in detail to highlight achieved levels of performance.

  13. "Scientific" Creationism Is Not Based on Scientific Research.

    ERIC Educational Resources Information Center

    Cole, Henry P.; Scott, Eugenie C.

    "Science Citation Index" is a service that lists the contents of over 3,000 of the most important science journals and proceedings. A computer search of the Index was conducted using the terms "creationism,""scientific creationism,""special creation,""biblical creation," as well as related terms. The file searched extended from January 1978 until…

  14. Scientific Utopia: An agenda for improving scientific communication (Invited)

    NASA Astrophysics Data System (ADS)

    Nosek, B.

    2013-12-01

    The scientist's primary incentive is publication. In the present culture, open practices do not increase chances of publication, and they often require additional work. Practicing the abstract scientific values of openness and reproducibility thus requires behaviors in addition to those relevant for the primary, concrete rewards. When in conflict, concrete rewards are likely to dominate over abstract ones. As a consequence, the reward structure for scientists does not encourage openness and reproducibility. This can be changed by nudging incentives to align scientific practices with scientific values. Science will benefit by creating and connecting technologies that nudge incentives while supporting and improving the scientific workflow. For example, it should be as easy to search the research literature for my topic as it is to search the Internet to find hilarious videos of cats falling off of furniture. I will introduce the Center for Open Science (http://centerforopenscience.org/) and efforts to improve openness and reproducibility such as http://openscienceframework.org/. There will be no cats.

  15. Confidence in ASCI scientific simulations

    SciTech Connect

    Ang, J.A.; Trucano, T.G.; Luginbuhl, D.R.

    1998-06-01

    The US Department of Energy`s (DOE) Accelerated Strategic Computing Initiative (ASCI) program calls for the development of high end computing and advanced application simulations as one component of a program to eliminate reliance upon nuclear testing in the US nuclear weapons program. This paper presents results from the ASCI program`s examination of needs for focused validation and verification (V and V). These V and V activities will ensure that 100 TeraOP-scale ASCI simulation code development projects apply the appropriate means to achieve high confidence in the use of simulations for stockpile assessment and certification. The authors begin with an examination of the roles for model development and validation in the traditional scientific method. The traditional view is that the scientific method has two foundations, experimental and theoretical. While the traditional scientific method does not acknowledge the role for computing and simulation, this examination establishes a foundation for the extension of the traditional processes to include verification and scientific software development that results in the notional framework known as Sargent`s Framework. This framework elucidates the relationships between the processes of scientific model development, computational model verification and simulation validation. This paper presents a discussion of the methodologies and practices that the ASCI program will use to establish confidence in large-scale scientific simulations. While the effort for a focused program in V and V is just getting started, the ASCI program has been underway for a couple of years. The authors discuss some V and V activities and preliminary results from the ALEGRA simulation code that is under development for ASCI. The breadth of physical phenomena and the advanced computational algorithms that are employed by ALEGRA make it a subject for V and V that should typify what is required for many ASCI simulations.

  16. Learning to use scientific concepts

    NASA Astrophysics Data System (ADS)

    Wells, Gordon

    2008-07-01

    In responding to the research on conceptual change, this article attempts to make two points. First, scientific concepts are not possessed by individuals; rather, they are part of a culture's resources, which individuals learn to use for their own or for group purposes. Second, particular concepts are most effectively mastered when the learner is deeply engaged in solving a problem for which they function as effective semiotic tools in achieving a solution. On these grounds, it is argued that the mastering of scientific concepts is best achieved through learning to use them in motivated inquiry.

  17. Chemical datuments as scientific enablers.

    PubMed

    Rzepa, Henry S

    2013-01-01

    This article is an attempt to construct a chemical datument as a means of presenting insights into chemical phenomena in a scientific journal. An exploration of the interactions present in a small fragment of duplex Z-DNA and the nature of the catalytic centre of a carbon-dioxide/alkene epoxide alternating co-polymerisation is presented in this datument, with examples of the use of three software tools, one based on Java, the other two using Javascript and HTML5 technologies. The implications for the evolution of scientific journals are discussed. PMID:23343381

  18. Chemical datuments as scientific enablers

    PubMed Central

    2013-01-01

    This article is an attempt to construct a chemical datument as a means of presenting insights into chemical phenomena in a scientific journal. An exploration of the interactions present in a small fragment of duplex Z-DNA and the nature of the catalytic centre of a carbon-dioxide/alkene epoxide alternating co-polymerisation is presented in this datument, with examples of the use of three software tools, one based on Java, the other two using Javascript and HTML5 technologies. The implications for the evolution of scientific journals are discussed. PMID:23343381

  19. Nuclear science. Annual report, July 1, 1980-June 30, 1981

    SciTech Connect

    Friedlander, E.M.

    1982-06-01

    This annual report describes the scientific research carried out within the Nuclear Science Division between July 1, 1980 and June 30, 1981. The principal activity of the division continues to be the experimental and theoretical investigation of the interaction of heavy ions with target nuclei. Complementary research programs in light-ion nuclear science, in nuclear data evaluations, and in the development of advanced instrumentation are also carried out.

  20. LDRD Annual Report FY2006

    SciTech Connect

    Sketchley, J A; Kotta, P; De Yoreo, J; Jackson, K; van Bibber, K

    2007-03-20

    The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Laboratory Science and Technology Office, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration in national security, energy security, environmental management, bioscience and technology to improve human health, and breakthroughs in fundamental science and technology. The accomplishments described in this Annual Report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $92 million for FY2006 sponsored 188 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest

  1. Export bill and scientific exchanges

    NASA Astrophysics Data System (ADS)

    President Ronald Reagan has signed into law the reauthorization of the Export Administration Act (EAA), first passed in 1979. The amended version of the law, signed July 12, includes a policy statement in support of “vigorous scientific enterprise. . .in accordance with applicable provisions of law. . .by means of publication, teaching, conferences, and other forms of scholarly exchange.”

  2. Communication; A Scientific American Book.

    ERIC Educational Resources Information Center

    Scientific American, Inc., New York, NY.

    With present advances in communication technology, profound and qualitative changes in our civilization are taking place--in business and politics, in education, in entertainment, interpersonal relations, and the organization of society itself. In honor of the significance of such developments, an entire issue of "Scientific American" magazine…

  3. Marbleized Paper: A Scientific Art.

    ERIC Educational Resources Information Center

    Grambo, Gregory

    1994-01-01

    Discusses marbleized paper, which originated in Japan in the eighth century and became quite popular in Europe and the United States in the nineteenth century. Describes the scientific process behind marbleization, and explains how students can produce their own colorful designs by placing a sheet of paper on top of oil-based paints floated in a…

  4. Final Technical and Scientific Report

    SciTech Connect

    Sanjay Krishna and Diana Huffaker

    2007-07-11

    The objective of this project is to study the ultrafast carrier dynamics of in two types of semiconductor quantum dots: self-assembled quantum dots (SAQDs) and patterned quantum dots (PQDs) and to correlate these dynamics with the shape, size and material composition of the dots, thereby obtaining a fundamental scientific understanding of these nanoscale systems.

  5. Going public: good scientific conduct.

    PubMed

    Meyer, Gitte; Sandøe, Peter

    2012-06-01

    The paper addresses issues of scientific conduct regarding relations between science and the media, relations between scientists and journalists, and attitudes towards the public at large. In the large and increasing body of literature on scientific conduct and misconduct, these issues seem underexposed as ethical challenges. Consequently, individual scientists here tend to be left alone with problems and dilemmas, with no guidance for good conduct. Ideas are presented about how to make up for this omission. Using a practical, ethical approach, the paper attempts to identify ways scientists might deal with ethical public relations issues, guided by a norm or maxim of openness. Drawing on and rethinking the CUDOS codification of the scientific ethos, as it was worked out by Robert K. Merton in 1942, we propose that this, which is echoed in current codifications of norms for good scientific conduct, contains a tacit maxim of openness which may naturally be extended to cover the public relations of science. Discussing openness as access, accountability, transparency and receptiveness, the argumentation concentrates on the possible prevention of misconduct with respect to, on the one hand, sins of omission-withholding important information from the public-and, on the other hand, abuses of the authority of science in order to gain publicity. Statements from interviews with scientists are used to illustrate how scientists might view the relevance of the issues raised. PMID:21088921

  6. Prevention Programs and Scientific Nonsense.

    ERIC Educational Resources Information Center

    Gorman, D. M.

    2003-01-01

    Discusses attempts to examine the scientific base of widely advocated prevention programs, describing how one professor experienced hostility when examining program evaluation data. It focuses on science and the learned theory; science, anti-science, and pseudo-science; anti-science and health promotion; pseudoscience and health promotion; and…

  7. LANGUAGE TEACHING, A SCIENTIFIC APPROACH.

    ERIC Educational Resources Information Center

    LADO, ROBERT

    DESIGNED TO UPDATE THE CONTEMPORARY LANGUAGE TEACHER'S KNOWLEDGE OF THE INNOVATIONS IN HIS FIELD, THIS BOOK INTRODUCES SOME OF THE ESSENTIAL MAJOR AREAS OF WHICH HE SHOULD HAVE AN UNDERSTANDING TO APPROACH HIS WORK SCIENTIFICALLY. PART ONE, DEALING IN GENERAL TERMS WITH LANGUAGE AND LANGUAGE LEARNING, SETS THE TONE OF THE BOOK WITH DISCUSSIONS OF…

  8. Strategic Scaffolding for Scientific Inquiry

    ERIC Educational Resources Information Center

    Shelton, Angela; Natarajan, Uma; Willard, Catherine; Kane, Tera; Ketelhut, Diane Jass; Schifter, Catherine

    2013-01-01

    Though many national and international science organizations stress the importance of integrating scientific inquiry into classroom instruction, this is often difficult for teachers. Moreover, assessing and scaffolding inquiry skills for students can be even more of a challenge. This paper investigated the student performances in an inquiry-based,…

  9. Population Control and Scientific Ethics.

    ERIC Educational Resources Information Center

    Stern, Zev

    1978-01-01

    Garrett Hardin, a trained biologist, made a plea for coercive population control in a prestigious scientific journal (Science, 1968). His theory on how to control population is examined, the net effects of a situational vs an absolute ethics is weighed, and the limits to science and its methodology are evaluated. (Author/RK)

  10. Academic Staff and Scientific Production.

    ERIC Educational Resources Information Center

    Kyvik, Svein

    1993-01-01

    A survey of tenured faculty in four Norwegian universities investigated publication and scientific productivity patterns in a three-year period. Analysis of results suggests underlying reasons for differences between individuals, age groups, and gender groups and implications for administrative policy to support productivity. (MSE)

  11. Electronic Delivery of Scientific Information.

    ERIC Educational Resources Information Center

    Hunter, Karen A.

    1984-01-01

    Summarizes market pressures and applications of use of electronic communication technology in scientific information dissemination and presents publishers' short-term response (electronic manuscript standardization, database orientation, provision of journal articles on demand, improvement of online search software); publishers' long-term response…

  12. Scientific Ethics in Chemical Education

    NASA Astrophysics Data System (ADS)

    Kovac, Jeffrey

    1996-10-01

    Scientific ethics is a subset of professional ethics, the special rules of conduct adhered to by people engaged in those pursuits called professions. It is distinct from, but consistent with, both ordinary morality and moral theory. The codes of professional ethics derive from the two bargains that define a profession: the internal code of practice and the external bargain between the profession and society. While the informal code of professional conduct is well understood by working scientists, it is rarely explicitly included in the chemistry curriculum. Instead, we have relied on informal methods to teach students scientific ethics, a strategy that is haphazard at best. In this paper I argue that scientific ethics can and must be taught as part of the chemistry curriculum and that this is the best done through the case-study method. Many decisions made by working scientists have both a technical and an ethical component. Students need to learn how to make good decisions in professional ethics. The alternative is, at best, sloppy science and, at worst, scientific misconduct.

  13. Scientific customer needs - NASA user

    NASA Technical Reports Server (NTRS)

    Black, David C.

    1987-01-01

    Some requirements for scientific users of the Space Station are considered. The use of testbeds to evaluate design concepts for information systems, and for interfacing between designers and builders of systems is examined. The need for an information system that provides an effective interaction between ground-based users and their space-based equipment is discussed.

  14. Biology, Philosophy, and Scientific Method.

    ERIC Educational Resources Information Center

    Hill, L.

    1985-01-01

    The limits of falsification are discussed and the historically based models of science described by Lakatos and Kuhn are shown to offer greater insights into the practice of science. The theory of natural selection is used to relate biology to philosophy and scientific method. (Author/JN)

  15. Scientific Reasoning: No Child's Play

    ERIC Educational Resources Information Center

    Cavanagh, Sean

    2009-01-01

    The students, from the Academy of the Americas, a public school a few miles from downtown, are being asked to do the painstaking work of science, in an unlikely setting. It's part of a curriculum and professional-development program called BioKIDS, which seeks to build students' skill in complex scientific reasoning. The approach goes well beyond…

  16. Scientific Assistant Virtual Laboratory (SAVL)

    NASA Astrophysics Data System (ADS)

    Alaghband, Gita; Fardi, Hamid; Gnabasik, David

    2007-03-01

    The Scientific Assistant Virtual Laboratory (SAVL) is a scientific discovery environment, an interactive simulated virtual laboratory, for learning physics and mathematics. The purpose of this computer-assisted intervention is to improve middle and high school student interest, insight and scores in physics and mathematics. SAVL develops scientific and mathematical imagination in a visual, symbolic, and experimental simulation environment. It directly addresses the issues of scientific and technological competency by providing critical thinking training through integrated modules. This on-going research provides a virtual laboratory environment in which the student directs the building of the experiment rather than observing a packaged simulation. SAVL: * Engages the persistent interest of young minds in physics and math by visually linking simulation objects and events with mathematical relations. * Teaches integrated concepts by the hands-on exploration and focused visualization of classic physics experiments within software. * Systematically and uniformly assesses and scores students by their ability to answer their own questions within the context of a Master Question Network. We will demonstrate how the Master Question Network uses polymorphic interfaces and C# lambda expressions to manage simulation objects.

  17. Scientific knowledge and modern prospecting

    USGS Publications Warehouse

    Neuerburg, G.J.

    1985-01-01

    Modern prospecting is the systematic search for specified and generally ill-exposed components of the Earth's crust known as ore. This prospecting depends entirely on reliable, or scientific knowledge for guidance and for recognition of the search objects. Improvement in prospecting results from additions and refinements to scientific knowledge. Scientific knowledge is an ordered distillation of observations too numerous and too complex in themselves for easy understanding and for effective management. The ordering of these observations is accomplished by an evolutionary hierarchy of abstractions. These abstractions employ simplified descriptions consisting of characterization by selected properties, sampling to represent much larger parts of a phenomenon, generalized mappings of patterns of geometrical and numerical relations among properties, and explanation (theory) of these patterns as functional relations among the selected properties. Each abstraction is predicated on the mode of abstraction anticipated for the next higher level, so that research is a deductive process in which the highest level, theory, is indispensible for the growth and refinement of scientific knowledge, and therefore of prospecting methodology. ?? 1985 Springer-Verlag.

  18. Scientific Creativity: Idealism versus Pragmatism

    ERIC Educational Resources Information Center

    Mumford, Michael D.; Hester, Kimberly S.; Robledo, Issac C.

    2010-01-01

    The need for creativity in the sciences has, from time to time, been questioned. Thus, Ghassib's (2010) argument that creativity is critical to performance in the sciences, and hence organizational effectiveness in a knowledge production economy, is important. Moreover, the proposition that scientific creativity is based on knowledge and…

  19. Sustainability Indicators: A Scientific Assessment

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The book entitled "Sustainability Indicators: A Scientific Assessment," which was a product of a multi-location research effort and workshoip held in Prague Czech Republic, is reviewed for readers of the Journal of Enviromental Quality (JEQ). The overview and chapters on biodiversity indicators and ...

  20. Learning Scientific Programming with Python

    NASA Astrophysics Data System (ADS)

    Hill, Christian

    2016-02-01

    1. Introduction; 2. The core Python language I; 3. Interlude: simple plotting with pylab; 4. The core Python language II; 5. IPython and IPython notebook; 6. NumPy; 7. Matplotlib; 8. SciPy; 9. General scientific programming; Appendix A; Solutions; Index.

  1. Figuring out a scientific understanding

    NASA Astrophysics Data System (ADS)

    Sutton, Clive

    1993-12-01

    This article attempts to place analogy and metaphor within the wider context of all figurative language, and to trace the relationship between that kind of expression and the supposedly literal and direct accounts of nature that scientists have built up.I explore the functions of figures of speech in the development of new scientific ideas, and trace how they fade or die as each area of scientific knowledge matures. What we then take to be the literal words of scientific description are in effect the remnants of old figures of speech that have grown so familiar that their earlier metaphorical quality is easily overlooked. The conventional separation of figurative and literal cannot be sustained, and a new understanding of their relationship is needed.The practical implications of this analysis are to do with how we can reactivate the dormant metaphors in ordinary scientific language, so that learners may hear again the human voice of scientists who developed the ways of talking we now take for granted. To reactivate the system of thought behind any established way of talking, we must be able to get the learners to understand that language works as a medium of interpretation and persuasion, and not simply a system of descriptive labeling. These two views of language are compared and contrasted.

  2. The Meaning of Scientific Literacy

    ERIC Educational Resources Information Center

    Holbrook, Jack; Rannikmae, Miia

    2009-01-01

    This paper sets out to provide an overview of scientific literacy specifically related to whether emphasis is placed on the "science" or the "literacy" aspect, accepting that literacy, wherever used, is wider than simply reading and writing. It does this from a general rather than a country perspective. The emphasis in giving meaning to scientific…

  3. Quantitative assessment of scientific quality

    NASA Astrophysics Data System (ADS)

    Heinzl, Harald; Bloching, Philipp

    2012-09-01

    Scientific publications, authors, and journals are commonly evaluated with quantitative bibliometric measures. Frequently-used measures will be reviewed and their strengths and weaknesses will be highlighted. Reflections about conditions for a new, research paper-specific measure will be presented.

  4. Annual Bibliography, 2000.

    ERIC Educational Resources Information Center

    Brown, Jo. B., Comp.

    2001-01-01

    Classified bibliography for Appalachian studies includes over 400 books, journal articles, and government documents published in 2000, plus 1999 citations not included previously. Emphasis is on the social sciences and education; highly technical and scientific studies and audiovisual titles are excluded. Brief explanations accompany many entries.…

  5. Promoting Science Learning and Scientific Identification through Contemporary Scientific Investigations

    NASA Astrophysics Data System (ADS)

    Van Horne, Katie

    This dissertation investigates the implementation issues and the educational opportunities associated with "taking the practice turn" in science education. This pedagogical shift focuses instructional experiences on engaging students in the epistemic practices of science both to learn the core ideas of the disciplines, as well as to gain an understanding of and personal connection to the scientific enterprise. In Chapter 2, I examine the teacher-researcher co-design collaboration that supported the classroom implementation of a year-long, project-based biology curriculum that was under development. This study explores the dilemmas that arose when teachers implemented a new intervention and how the dilemmas arose and were managed throughout the collaboration of researchers and teachers and between the teachers. In the design-based research of Chapter 3, I demonstrate how students' engagement in epistemic practices in contemporary science investigations supported their conceptual development about genetics. The analysis shows how this involved a complex interaction between the scientific, school and community practices in students' lives and how through varied participation in the practices students come to write about and recognize how contemporary investigations can give them leverage for science-based action outside of the school setting. Finally, Chapter 4 explores the characteristics of learning environments for supporting the development of scientific practice-linked identities. Specific features of the learning environment---access to the intellectual work of the domain, authentic roles and accountability, space to make meaningful contributions in relation to personal interests, and practice-linked identity resources that arose from interactions in the learning setting---supported learners in stabilizing practice-linked science identities through their engagement in contemporary scientific practices. This set of studies shows that providing students with the

  6. Annual Energy Review 2007

    SciTech Connect

    Seiferlein, Katherine E.

    2008-06-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....”

  7. Coal industry annual 1997

    SciTech Connect

    1998-12-01

    Coal Industry Annual 1997 provides comprehensive information about US coal production, number of mines, prices, productivity, employment, productive capacity, and recoverable reserves. US Coal production for 1997 and previous years is based on the annual survey EIA-7A, Coal Production Report. This report presents data on coal consumption, coal distribution, coal stocks, coal prices, and coal quality for Congress, Federal and State agencies, the coal industry, and the general public. Appendix A contains a compilation of coal statistics for the major coal-producing States. This report includes a national total coal consumption for nonutility power producers that are not in the manufacturing, agriculture, mining, construction, or commercial sectors. 14 figs., 145 tabs.

  8. International energy annual 1997

    SciTech Connect

    1999-04-01

    The International Energy Annual presents an overview of key international energy trends for production, consumption, imports, and exports of primary energy commodities in over 220 countries, dependencies, and areas of special sovereignty. Also included are population and gross domestic product data, as well as prices for crude oil and petroleum products in selected countries. Renewable energy reported in the International Energy Annual includes hydroelectric power and geothermal, solar, and wind electric power. Also included are biomass electric power for Brazil and the US, and biomass, geothermal, and solar energy produced in the US and not used for electricity generation. This report is published to keep the public and other interested parties fully informed of primary energy supplies on a global basis. The data presented have been largely derived from published sources. The data have been converted to units of measurement and thermal values (Appendices E and F) familiar to the American public. 93 tabs.

  9. Renewable energy annual 1995

    SciTech Connect

    1995-12-01

    The Renewable Energy Annual 1995 is the first in an expected series of annual reports the Energy Information Administration (EIA) intends to publish to provide a comprehensive assessment of renewable energy. This report presents the following information on the history, status, and prospects of renewable energy data: estimates of renewable resources; characterizations of renewable energy technologies; descriptions of industry infrastructures for individual technologies; evaluations of current market status; and assessments of near-term prospects for market growth. An international section is included, as well as two feature articles that discuss issues of importance for renewable energy as a whole. The report also contains a number of technical appendices and a glossary. The renewable energy sources included are biomass (wood), municipal solid waste, biomass-derived liquid fuels, geothermal, wind, and solar and photovoltaic.

  10. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... scientific research are requested to submit a copy of any cruise report or other publication created as a... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities...

  11. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... scientific research are requested to submit a copy of any cruise report or other publication created as a... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities...

  12. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities on board a scientific research vessel in the EEZ that may be confused with fishing are encouraged to...

  13. 50 CFR 35.11 - Scientific uses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... uses. Recognizing the scientific value of wilderness, research data gathering and similar scientific... location and size of the area to be used for research purposes. A special use permit authorizing scientific... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false Scientific uses. 35.11 Section...

  14. 50 CFR 35.11 - Scientific uses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... uses. Recognizing the scientific value of wilderness, research data gathering and similar scientific... location and size of the area to be used for research purposes. A special use permit authorizing scientific... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false Scientific uses. 35.11 Section...

  15. 50 CFR 35.11 - Scientific uses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... uses. Recognizing the scientific value of wilderness, research data gathering and similar scientific... location and size of the area to be used for research purposes. A special use permit authorizing scientific... 50 Wildlife and Fisheries 9 2014-10-01 2014-10-01 false Scientific uses. 35.11 Section...

  16. 50 CFR 35.11 - Scientific uses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... uses. Recognizing the scientific value of wilderness, research data gathering and similar scientific... location and size of the area to be used for research purposes. A special use permit authorizing scientific... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Scientific uses. 35.11 Section...

  17. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities on board a scientific research vessel in the EEZ that may be confused with fishing are encouraged to...

  18. 50 CFR 35.11 - Scientific uses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... uses. Recognizing the scientific value of wilderness, research data gathering and similar scientific... location and size of the area to be used for research purposes. A special use permit authorizing scientific... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false Scientific uses. 35.11 Section...

  19. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 12 2012-10-01 2012-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities on board a scientific research vessel in the EEZ that may be confused with fishing are encouraged to...

  20. Annual Energy Outlook

    EIA Publications

    2016-01-01

    Projections in the Annual Energy Outlook 2016 (AEO2016) focus on the factors expected to shape U.S. energy markets through 2040. The projections provide a basis for examination and discussion of energy market trends and serve as a starting point for analysis of potential changes in U.S. energy policies, rules, and regulations, as well as the potential role of advanced technologies.

  1. 2008 annual merit review

    SciTech Connect

    None, None

    2009-01-18

    The 2008 DOE Vehicle Technologies Program Annual Merit Review was held February 25-28, 2008 in Bethesda, Maryland. The review encompassed all of the work done by the Vehicle Technologies Program: a total of 280 individual activities were reviewed, by a total of just over 100 reviewers. A total of 1,908 individual review responses were received for the technical reviews, and an additional 29 individual review responses were received for the plenary session review.

  2. Uranium industry annual 1995

    SciTech Connect

    1996-05-01

    The Uranium Industry Annual 1995 (UIA 1995) provides current statistical data on the U.S. uranium industry`s activities relating to uranium raw materials and uranium marketing. The UIA 1995 is prepared for use by the Congress, Federal and State agencies, the uranium and nuclear electric utility industries, and the public. It contains data for the period 1986 through 2005 as collected on the Form EIA-858, ``Uranium Industry Annual Survey``. Data collected on the ``Uranium Industry Annual Survey`` provide a comprehensive statistical characterization of the industry`s plans and commitments for the near-term future. Where aggregate data are presented in the UIA 1995, care has been taken to protect the confidentiality of company-specific information while still conveying accurate and complete statistical data. Data on uranium raw materials activities for 1986 through 1995 including exploration activities and expenditures, EIA-estimated reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities for 1994 through 2005, including purchases of uranium and enrichment services, enrichment feed deliveries, uranium fuel assemblies, filled and unfilled market requirements, uranium imports and exports, and uranium inventories are shown in Chapter 2. The methodology used in the 1995 survey, including data edit and analysis, is described in Appendix A. The methodologies for estimation of resources and reserves are described in Appendix B. A list of respondents to the ``Uranium Industry Annual Survey`` is provided in Appendix C. For the reader`s convenience, metric versions of selected tables from Chapters 1 and 2 are presented in Appendix D along with the standard conversion factors used. A glossary of technical terms is at the end of the report. 14 figs., 56 tabs.

  3. Uranium industry annual 1994

    SciTech Connect

    1995-07-05

    The Uranium Industry Annual 1994 (UIA 1994) provides current statistical data on the US uranium industry`s activities relating to uranium raw materials and uranium marketing during that survey year. The UIA 1994 is prepared for use by the Congress, Federal and State agencies, the uranium and nuclear electric utility industries, and the public. It contains data for the 10-year period 1985 through 1994 as collected on the Form EIA-858, ``Uranium Industry Annual Survey.`` Data collected on the ``Uranium Industry Annual Survey`` (UIAS) provide a comprehensive statistical characterization of the industry`s activities for the survey year and also include some information about industry`s plans and commitments for the near-term future. Where aggregate data are presented in the UIA 1994, care has been taken to protect the confidentiality of company-specific information while still conveying accurate and complete statistical data. A feature article, ``Comparison of Uranium Mill Tailings Reclamation in the United States and Canada,`` is included in the UIA 1994. Data on uranium raw materials activities including exploration activities and expenditures, EIA-estimated resources and reserves, mine production of uranium, production of uranium concentrate, and industry employment are presented in Chapter 1. Data on uranium marketing activities, including purchases of uranium and enrichment services, and uranium inventories, enrichment feed deliveries (actual and projected), and unfilled market requirements are shown in Chapter 2.

  4. G.V. Schiaparelli: from scientific observations to scientific imagination

    NASA Astrophysics Data System (ADS)

    Giorello, G.; Guzzardi, L.

    Starting with a letter exchange between Schiaparelli and the German physicist, physiologist and philosopher Ernst Mach, we discuss some aspects of Schiaparelli's non-astronomical scientific activity. In particular, we give an account of his Studio comparativo tra le forme organiche naturali e le forme geometriche pure (Hoepli, Milano 1898), where he sought to represent organic forms and the change from one species to another through geometry. Since his Studio provides one of the first examples of an application of mathematics to biology, we analyze it in the light of the geometric-crystallographic approach to biology which flourished in the 19th-century life sciences. Finally we connect his biological interests with astronomy and show how his methodological perspective, which appears also in the letter exchange with Mach, emerges from his scientific activity. In the conclusions we discuss the role of imagination in Schiaparelli's view.

  5. Scientific and non-scientific challenges for Operational Earthquake Forecasting

    NASA Astrophysics Data System (ADS)

    Marzocchi, W.

    2015-12-01

    Tracking the time evolution of seismic hazard in time windows shorter than the usual 50-years of long-term hazard models may offer additional opportunities to reduce the seismic risk. This is the target of operational earthquake forecasting (OEF). During the OEF development in Italy we identify several challenges that range from pure science to the more practical interface of science with society. From a scientific point of view, although earthquake clustering is the clearest empirical evidence about earthquake occurrence, and OEF clustering models are the most (successfully) tested hazard models in seismology, we note that some seismologists are still reluctant to accept their scientific reliability. After exploring the motivations of these scientific doubts, we also look into an issue that is often overlooked in this discussion, i.e., in any kind of hazard analysis, we do not use a model because it is the true one, but because it is the better than anything else we can think of. The non-scientific aspects are mostly related to the fact that OEF usually provides weekly probabilities of large eartquakes smaller than 1%. These probabilities are considered by some seismologists too small to be of interest or useful. However, in a recent collaboration with engineers we show that such earthquake probabilities may lead to intolerable individual risk of death. Interestingly, this debate calls for a better definition of the still fuzzy boundaries among the different expertise required for the whole risk mitigation process. The last and probably more pressing challenge is related to the communication to the public. In fact, a wrong message could be useless or even counterproductive. Here we show some progresses that we have made in this field working with communication experts in Italy.

  6. Scientific Process Automation Improves Data Interaction

    SciTech Connect

    Critchlow, Terence J.

    2009-09-30

    This is an article written for the September 09 Scientific Computing magazine about the work of the Scientific Process Automation team of The U.S. Department of Energy (DOE) Scientific Discovery through Advanced Computing (SciDAC) program. The SPA team is focused on developing and deploying automated workflows for a variety of computational science domains. Scientific workflows are the formalization of a scientific process that is frequently and repetitively performed.

  7. Advanced Scientific Computing Environment Team new scientific database management task

    SciTech Connect

    Church, J.P.; Roberts, J.C.; Sims, R.N.; Smetana, A.O.; Westmoreland, B.W.

    1991-06-01

    The mission of the ASCENT Team is to continually keep pace with, evaluate, and select emerging computing technologies to define and implement prototypic scientific environments that maximize the ability of scientists and engineers to manage scientific data. These environments are to be implemented in a manner consistent with the site computing architecture and standards and NRTSC/SCS strategic plans for scientific computing. The major trends in computing hardware and software technology clearly indicate that the future computer'' will be a network environment that comprises supercomputers, graphics boxes, mainframes, clusters, workstations, terminals, and microcomputers. This network computer'' will have an architecturally transparent operating system allowing the applications code to run on any box supplying the required computing resources. The environment will include a distributed database and database managing system(s) that permits use of relational, hierarchical, object oriented, GIS, et al, databases. To reach this goal requires a stepwise progression from the present assemblage of monolithic applications codes running on disparate hardware platforms and operating systems. The first steps include converting from the existing JOSHUA system to a new J80 system that complies with modern language standards, development of a new J90 prototype to provide JOSHUA capabilities on Unix platforms, development of portable graphics tools to greatly facilitate preparation of input and interpretation of output; and extension of Jvv'' concepts and capabilities to distributed and/or parallel computing environments.

  8. Addressing Unconscious Bias: Steps toward an Inclusive Scientific Culture

    NASA Astrophysics Data System (ADS)

    Stewart, Abigail

    2011-01-01

    In this talk I will outline the nature of unconscious bias, as it operates to exclude or marginalize some participants in the scientific community. I will show how bias results from non-conscious expectations about certain groups of people, including scientists and astronomers. I will outline scientific research in psychology, sociology and economics that has identified the impact these expectations have on interpersonal judgments that are at the heart of assessment of individuals' qualifications. This research helps us understand not only how bias operates within a single instance of evaluation, but how evaluation bias can accumulate over a career if not checked, creating an appearance of confirmation of biased expectations. Some research has focused on how best to interrupt and mitigate unconscious bias, and many institutions--including the University of Michigan--have identified strategic interventions at key points of institutional decision-making (particularly hiring, annual review, and promotion) that can make a difference. The NSF ADVANCE Institutional Transformation program encouraged institutions to draw on the social science literature to create experimental approaches to addressing unconscious bias. I will outline four approaches to intervention that have arisen through the ADVANCE program: (1) systematic education that increases awareness among decisionmakers of how evaluation bias operates; (2) development of practices that mitigate the operation of bias even when it is out of conscious awareness; (3) creation of institutional policies that routinize and sanction these practices; and (4) holding leaders accountable for these implementation of these new practices and policies. Although I will focus on ways to address unconscious bias within scientific institutions (colleges and universities, laboratories and research centers, etc.), I will close by considering how scientific organizations can address unconscious bias and contribute to creating an

  9. Scientific opportunities in nuclear resonance spectroscopy from source-driven revolution.

    SciTech Connect

    Shenoy, G. K.; Rohlsberger, R.; X-Ray Science Division; DESY

    2008-02-01

    From the beginning of its discovery the Moessbauer effect has continued to be one of the most powerful tools with broad applications in diverse areas of science and technology. With the advent of synchrotron radiation sources such as the Advanced Photon Source (APS), the European Synchrotron Radiation Facility (ESRF) and the Super Photon Ring-8 (SPring-8), the tool has enlarged its scope and delivered new capabilities. The popular techniques most generally used in the field of materials physics, chemical physics, geoscience, and biology are hyperfine spectroscopy via elastic nuclear forward scattering (NFS), vibrational spectroscopy via nuclear inelastic scattering (NRIXS), and, to a lesser extent, diffusional dynamics from quasielastic nuclear forward scattering (QNFS). As we look ahead, new storage rings with enhanced brilliance such as PETRA-III under construction at DESY, Hamburg, and PEP-III in its early design stage at SLAC, Stanford, will provide new and unique science opportunities. In the next two decades, x-ray free-electron lasers (XFELs), based both on self-amplified spontaneous emission (SASE-XFELs) and a seed (SXFELs), with unique time structure, coherence and a five to six orders higher average brilliance will truly revolutionize nuclear resonance applications in a major way. This overview is intended to briefly address the unique radiation characteristics of new sources on the horizon and to provide a glimpse of scientific prospects and dreams in the nuclear resonance field from the new radiation sources. We anticipate an expanded nuclear resonance research activity with applications such as spin and phonon mapping of a single nanostructure and their assemblies, interfaces, and surfaces; spin dynamics; nonequilibrium dynamics; photochemical reactions; excited-state spectroscopy; and nonlinear phenomena.

  10. The pacific chapter annual meeting of the undersea & hyperbaric medical society

    PubMed Central

    2011-01-01

    The following is the summary report on the UHMS Pacific Chapter Annual Meeting held in Long Beach in October 2010. The conference provided the latest updates on scientific, technical and organizational aspects of Hyperbaric and Diving Medicine. Invited speakers gave series of lectures dealing with current standards of clinical practice and presenting the results of laboratory investigations with particular emphasis on mechanisms of hyperbaric oxygen therapy. Scientific sessions were accompanied by vendor exhibits and social events. PMID:22146426

  11. Performance Engineering Technology for Scientific Component Software

    SciTech Connect

    Malony, Allen D.

    2007-05-08

    Large-scale, complex scientific applications are beginning to benefit from the use of component software design methodology and technology for software development. Integral to the success of component-based applications is the ability to achieve high-performing code solutions through the use of performance engineering tools for both intra-component and inter-component analysis and optimization. Our work on this project aimed to develop performance engineering technology for scientific component software in association with the DOE CCTTSS SciDAC project (active during the contract period) and the broader Common Component Architecture (CCA) community. Our specific implementation objectives were to extend the TAU performance system and Program Database Toolkit (PDT) to support performance instrumentation, measurement, and analysis of CCA components and frameworks, and to develop performance measurement and monitoring infrastructure that could be integrated in CCA applications. These objectives have been met in the completion of all project milestones and in the transfer of the technology into the continuing CCA activities as part of the DOE TASCS SciDAC2 effort. In addition to these achievements, over the past three years, we have been an active member of the CCA Forum, attending all meetings and serving in several working groups, such as the CCA Toolkit working group, the CQoS working group, and the Tutorial working group. We have contributed significantly to CCA tutorials since SC'04, hosted two CCA meetings, participated in the annual ACTS workshops, and were co-authors on the recent CCA journal paper [24]. There are four main areas where our project has delivered results: component performance instrumentation and measurement, component performance modeling and optimization, performance database and data mining, and online performance monitoring. This final report outlines the achievements in these areas for the entire project period. The submitted progress

  12. The scientific observatories on Mont Blanc.

    PubMed

    Richalet, J P

    2001-01-01

    team of the Association pour la Recherche en Physiologie de l'Environnement (ARPE) renovated the observatory and started to organize annual scientific expeditions. PMID:11252700

  13. Publication ethics and scientific misconduct.

    PubMed

    Peh, W C G; Ng, K H

    2010-12-01

    To maintain the readers' trust and to uphold the journal's reputation, it is paramount for the entire research, peer reviewer and publication process to follow ethical principles and decisions. Studies involving humans, animals, medical records and human tissues/organs need to be conducted ethically, and the appropriate approvals obtained. The privacy and confidentiality of patients, authors and reviewers should be respected. When required, rights and permissions should be sought. Common forms of scientific misconduct include misappropriation of ideas, violation of generally accepted research practices, failure to comply with legislative and regulatory requirements, falsification of data, and inappropriate behaviour in relation to misconduct. Authors can expect editorial action to be taken, should duplicate publication, plagiarism and other forms of scientific misconduct be attempted or detected. PMID:21221494

  14. [Scientific concepts in clinical medicine].

    PubMed

    Rogler, G

    2003-11-28

    The understanding of the scientific basis and the theory of knowledge are surprisingly heterogeneous in practical and clinical medicine. It is frequently influenced or based on the philosophical theory of critical rationalism founded by Sir Karl Popper. Because the theory of knowledge and the understanding of scientific truth is the central basis for cautious and good clinical practise it is necessary to discuss both points to avoid unscientific auto-immunisation against critique in a type of medicine that regards herself as science-based. Evidence-based medicine would not be possible without interpretation and explanation of existing data into the individual treatment context. Besides an inductive or deductive logic the historical and situative side-conditions of the gathering of knowledge and of experiments are of central importance for their interpretation and their relevance in clinical practice. This historical and situative context warrants reflection but must also be paid attention to in the reflections on medical ethics. PMID:14648440

  15. Genealogical Trees of Scientific Papers

    PubMed Central

    Waumans, Michaël Charles; Bersini, Hugues

    2016-01-01

    Many results have been obtained when studying scientific papers citations databases in a network perspective. Articles can be ranked according to their current in-degree and their future popularity or citation counts can even be predicted. The dynamical properties of such networks and the observation of the time evolution of their nodes started more recently. This work adopts an evolutionary perspective and proposes an original algorithm for the construction of genealogical trees of scientific papers on the basis of their citation count evolution in time. The fitness of a paper now amounts to its in-degree growing trend and a “dying” paper will suddenly see this trend declining in time. It will give birth and be taken over by some of its most prevalent citing “offspring”. Practically, this might be used to trace the successive published milestones of a research field. PMID:26954677

  16. Activity detection in scientific visualization.

    PubMed

    Ozer, Sedat; Silver, Deborah; Bemis, Karen; Martin, Pino

    2014-03-01

    For large-scale simulations, the data sets are so massive that it is sometimes not feasible to view the data with basic visualization methods, let alone explore all time steps in detail. Automated tools are necessary for knowledge discovery, i.e., to help sift through the data and isolate specific time steps that can then be further explored. Scientists study patterns and interactions and want to know when and where interesting things happen. Activity detection, the detection of specific interactions of objects which span a limited duration of time, has been an active research area in the computer vision community. In this paper, we introduce activity detection to scientific simulations and show how it can be utilized in scientific visualization. We show how activity detection allows a scientist to model an activity and can then validate their hypothesis on the underlying processes. Three case studies are presented. PMID:24434219

  17. Scientific Freedom and Human Rights

    NASA Astrophysics Data System (ADS)

    Munoz, Elisa

    2000-03-01

    As part of her ongoing work monitoring issues at the intersection of science and human rights, Ms. Munoz has highlighted violations of academic freedom in Serbia and Iran, the denial of visas and travel licenses to U.S. and Cuban scientists, interference with scientific freedom in Brazil, Mexico, Russia, and the Ukraine, the use of organs from executed prisoners in China, legislation jeopardizing women's health in Iran, and the closure of centers for the treatment of torture survivors in Turkey. Such violations contravene international human rights principles listed in the Universal Declaration of Human Rights and other international human rights covenants. Ms. Munoz will describe current violations of scientific freedom and the relevant international principles on which these freedoms rest.

  18. Parallel processing for scientific computations

    NASA Technical Reports Server (NTRS)

    Alkhatib, Hasan S.

    1991-01-01

    The main contribution of the effort in the last two years is the introduction of the MOPPS system. After doing extensive literature search, we introduced the system which is described next. MOPPS employs a new solution to the problem of managing programs which solve scientific and engineering applications on a distributed processing environment. Autonomous computers cooperate efficiently in solving large scientific problems with this solution. MOPPS has the advantage of not assuming the presence of any particular network topology or configuration, computer architecture, or operating system. It imposes little overhead on network and processor resources while efficiently managing programs concurrently. The core of MOPPS is an intelligent program manager that builds a knowledge base of the execution performance of the parallel programs it is managing under various conditions. The manager applies this knowledge to improve the performance of future runs. The program manager learns from experience.

  19. Virtual Environments in Scientific Visualization

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Lisinski, T. A. (Technical Monitor)

    1994-01-01

    Virtual environment technology is a new way of approaching the interface between computers and humans. Emphasizing display and user control that conforms to the user's natural ways of perceiving and thinking about space, virtual environment technologies enhance the ability to perceive and interact with computer generated graphic information. This enhancement potentially has a major effect on the field of scientific visualization. Current examples of this technology include the Virtual Windtunnel being developed at NASA Ames Research Center. Other major institutions such as the National Center for Supercomputing Applications and SRI International are also exploring this technology. This talk will be describe several implementations of virtual environments for use in scientific visualization. Examples include the visualization of unsteady fluid flows (the virtual windtunnel), the visualization of geodesics in curved spacetime, surface manipulation, and examples developed at various laboratories.

  20. Annual ADP planning document

    NASA Technical Reports Server (NTRS)

    Mogilevsky, M.

    1973-01-01

    The Category A computer systems at KSC (Al and A2) which perform scientific and business/administrative operations are described. This data division is responsible for scientific requirements supporting Saturn, Atlas/Centaur, Titan/Centaur, Titan III, and Delta vehicles, and includes realtime functions, Apollo-Soyuz Test Project (ASTP), and the Space Shuttle. The work is performed chiefly on the GEL-635 (Al) system located in the Central Instrumentation Facility (CIF). The Al system can perform computations and process data in three modes: (1) real-time critical mode; (2) real-time batch mode; and (3) batch mode. The Division's IBM-360/50 (A2) system, also at the CIF, performs business/administrative data processing such as personnel, procurement, reliability, financial management and payroll, real-time inventory management, GSE accounting, preventive maintenance, and integrated launch vehicle modification status.

  1. Biology and Medicine Division annual report, 1987

    SciTech Connect

    Not Available

    1988-04-01

    Modern biology is characterized by rapid change. The development of new tools and the results derived from their application to various biological systems require significant shifts in our concepts and the strategies that are adopted to analyze and elucidate mechanisms. In parallel with exciting new scientific developments our organizational structure and programmatic emphases have altered. These changes and developments have enabled the life sciences at LBL to be better positioned to create and respond to new opportunities. The work summarized in this annual report reflects a vital multifaceted research program that is in the vanguard of the areas represented. We are committed to justifying the confidence expressed by LBL through the new mission statement and reorganizational changes designed to give greater prominence to the life sciences.

  2. AGU's 2010 annual report now available online

    NASA Astrophysics Data System (ADS)

    Buhrman, Joan

    2011-11-01

    AGU president Michael McPhaden, in a letter introducing the Union's recently released 2010 annual report, said that "2010 was a historic year for Earth and space science, and for AGU as an organization." He went on to say, "It is my honor to report on how our organization addressed challenges and created opportunities for growth and advancement throughout 2010, building on our core strengths of scientific excellence and groundbreaking research." The report tells the story of AGU's science and its commitment to promoting discovery in Earth and space science for the benefit of humanity through a series of profiles of individual members. The profiles focus on the impact these scientists' work is having on the world around them and how it relates to the goals outlined in AGU's new strategic plan.

  3. John B. Little Center Annual Symposium

    SciTech Connect

    Demple, Bruce F.

    2007-11-02

    The Annual Symposium of the John B. Little Center for Radiation Sciences and Environmental Health at the Harvard School of Public Health seeks to educate radiobiologists and biomedical scientists in related areas on the leading research related to the effects of ionizing radiation and related environmental agents in biological systems. This effort seeks to further the training of individuals in this field, and to foment productive interactions and collaborations among scientists at Harvard and with other institutions. The Symposium attracts world-class scientists as speakers, and a broad cross-section of attendees from academic, government, and industrial research centers, as well as editorial staff from leading scientific publications. In order to maintain this quality, funding to support the travel and local expenses of invited speakers is sought, along with funds to allow use of appropriate conference facilities.

  4. Hazards Control Department 1996 Annual Report

    SciTech Connect

    Richards, J.

    1997-06-30

    This annual report on the activities of the Hazards Control Department (HCD) in 1996 is part of the department's continuing effort to foster a working environment at Lawrence Livermore National Laboratory where every person has the means, ability, and desire to work safely. The significant accomplishments and activities, the various services provided, and research into Environment, Safety, and Health (ES&H) issues by HCD would not have been possible without the many and ongoing contributions by its employees and support personnel. The HCD Leadership Team thanks each and every one in the department for their efforts and work in 1996 and for their personal commitment to keeping one of the premier research and scientific institutions in the world today a safe and healthy place.

  5. Annual Report 2000. Chemical Structure and Dynamics

    SciTech Connect

    Colson, Steven D.; McDowell, Robin S.

    2001-04-15

    This annual report describes the research and accomplishments of the Chemical Structure and Dynamics Program in the year 2000, one of six research programs at the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) - a multidisciplinary, national scientific user facility and research organization. The Chemical Structure and Dynamics (CS&D) program is meeting the need for a fundamental, molecular-level understanding by 1) extending the experimental characterization and theoretical description of chemical reactions to encompass the effects of condensed media and interfaces; 2) developing a multidisciplinary capability for describing interfacial chemical processes relevant to environmental chemistry; and 3) developing state-of-the-art research and analytical methods for characterizing complex materials of the types found in natural and contaminated systems.

  6. Annual Report 2000. Chemical Structure and Dynamics

    SciTech Connect

    Colson, Steve D; McDowell, Rod S

    2001-04-15

    This annual report describes the research and accomplishments of the Chemical Structure and Dynamics Program in the year 2000, one of six research programs at the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) - a multidisciplinary, national scientific user facility and research organization. The Chemical Structure and Dynamics (CS and D) program is meeting the need for a fundamental, molecular-level understanding by (1) extending the experimental characterization and theoretical description of chemical reactions to encompass the effects of condensed media and interfaces; (2) developing a multidisciplinary capability for describing interfacial chemical processes relevant to environmental chemistry; and (3) developing state-of-the-art research and analytical methods for characterizing complex materials of the types found in natural and contaminated systems.

  7. NOAA's Scientific Data Stewardship Program

    NASA Astrophysics Data System (ADS)

    Bates, J. J.

    2004-12-01

    The NOAA mission is to understand and predict changes in the Earth's environment and conserve and manage coastal and marine resources to meet the Nation's economic, social and environmental needs. NOAA has responsibility for long-term archiving of the United States environmental data and has recently integrated several data management functions into a concept called Scientific Data Stewardship. Scientific Data Stewardship a new paradigm in data management consisting of an integrated suite of functions to preserve and exploit the full scientific value of NOAA's, and the world's, environmental data These functions include careful monitoring of observing system performance for long-term applications, the generation of authoritative long-term climate records from multiple observing platforms, and the proper archival of and timely access to data and metadata. NOAA has developed a conceptual framework to implement the functions of scientific data stewardship. This framework has five objectives: 1) develop real-time monitoring of all satellite observing systems for climate applications, 2) process large volumes of satellite data extending up to decades in length to account for systematic errors and to eliminate artifacts in the raw data (referred to as fundamental climate data records, FCDRs), 3) generate retrieved geophysical parameters from the FCDRs (referred to as thematic climate data records TCDRs) including combining observations from all sources, 4) conduct monitoring and research by analyzing data sets to uncover climate trends and to provide evaluation and feedback for steps 2) and 3), and 5) provide archives of metadata, FCDRs, and TCDRs, and facilitate distribution of these data to the user community. The term `climate data record' and related terms, such as climate data set, have been used for some time, but the climate community has yet to settle on a concensus definition. A recent United States National Academy of Sciences report recommends using the

  8. A Guide to Scientific Crowdfunding

    PubMed Central

    Vachelard, Julien; Gambarra-Soares, Thaise; Augustini, Gabriela; Riul, Pablo; Maracaja-Coutinho, Vinicius

    2016-01-01

    Crowdfunding represents an attractive new option for funding research projects, especially for students and early-career scientists or in the absence of governmental aid in some countries. The number of successful science-related crowdfunding campaigns is growing, which demonstrates the public’s willingness to support and participate in scientific projects. Putting together a crowdfunding campaign is not trivial, however, so here is a guide to help you make yours a success. PMID:26886064

  9. Tunisian women in scientific research

    NASA Astrophysics Data System (ADS)

    Jaziri, Sihem

    2013-03-01

    The number of Tunisian women conducting scientific research is comparable to that of countries where educating girls has been going on much longer. Although women play an increasingly important role in the field of research, they rarely hold positions of responsibility. Enormous similarities exist between the degree of integration of Tunisian women in science and technology and that of developed countries. Since independence and the removal of discrimination between girls and boys, Tunisian women have been catching up very quickly.

  10. A Guide to Scientific Crowdfunding.

    PubMed

    Vachelard, Julien; Gambarra-Soares, Thaise; Augustini, Gabriela; Riul, Pablo; Maracaja-Coutinho, Vinicius

    2016-02-01

    Crowdfunding represents an attractive new option for funding research projects, especially for students and early-career scientists or in the absence of governmental aid in some countries. The number of successful science-related crowdfunding campaigns is growing, which demonstrates the public's willingness to support and participate in scientific projects. Putting together a crowdfunding campaign is not trivial, however, so here is a guide to help you make yours a success. PMID:26886064

  11. PREFACE: Scientific and Publishing Editors

    NASA Astrophysics Data System (ADS)

    2016-02-01

    1.Scientific Editors Section 1: Particle physics Mikhail Skorohvatov - NRC Kurchatov Institute, Moscow, Russia Section 2: Nuclear physics Mikhail Danilov - ITEP NRC Kurchatov Institute, Moscow, Russia Section 3: Cosmic rays Arkady Galper - NRNU MEPhI, Moscow, Russia Anatoly Petrukhin - NRNU MEPhI, Moscow, Russia Section 4: Methods of experimental physics Valery Dmitrenko - NRNU MEPhI, Moscow, Russia 2.Publishing Editors Irene Arkhangelskaja - NRNU MEPhI, Moscow, Russia Pavel Buzhan - NRNU MEPhI, Moscow, Russia

  12. TRANSGENERATIONAL EXPOSURE TO TRENBOLONE IN JAPANESE MEDAKA: IN OVO VERSUS HATCHLING EXPOSURE SETAC 22 ANNUAL MEETING, BALTIMORE, MD NOVEMBER 11-15, 2001

    EPA Science Inventory

    . Transgenerational Exposure to Trenbolone in Japanese Medaka: In Ovo Versus Hatchling Exposure (Abstract). To be presented at the 22nd Annual Meeting of the Society of Environmental Toxicology and Chemistry: Changing Environmental Awareness: Societal Concerns and Scientific Resp...

  13. Accelerating scientific publication in biology.

    PubMed

    Vale, Ronald D

    2015-11-01

    Scientific publications enable results and ideas to be transmitted throughout the scientific community. The number and type of journal publications also have become the primary criteria used in evaluating career advancement. Our analysis suggests that publication practices have changed considerably in the life sciences over the past 30 years. More experimental data are now required for publication, and the average time required for graduate students to publish their first paper has increased and is approaching the desirable duration of PhD training. Because publication is generally a requirement for career progression, schemes to reduce the time of graduate student and postdoctoral training may be difficult to implement without also considering new mechanisms for accelerating communication of their work. The increasing time to publication also delays potential catalytic effects that ensue when many scientists have access to new information. The time has come for life scientists, funding agencies, and publishers to discuss how to communicate new findings in a way that best serves the interests of the public and the scientific community. PMID:26508643

  14. Scientific papers: A new paradigm

    NASA Astrophysics Data System (ADS)

    Reid, George C.

    The problem of how to organize and write a scientific paper is a very basic one for most of us. A scientific paper is, after all, the only tangible product of a research scientist and, like all products, will be a failure if not marketed properly to reach its potential buyers. I think that a lack of attention to this “marketing and sales” aspect of research is a serious fault in our community, by which I mean those of us who publish in AGU journals.The potential audience for a scientific paper can be divided roughly into three distinct categories. The first group is usually rather small in number, consisting of fellow scientists working in a very closely related field, and to whom the details of the work are of major importance. The second group is also fellow scientists, but their interest is less sharply focused, and they are concerned with the broad outlines of the work and essential results. The third group is the sponsors and the people who actually pay for the work, whose interest in the details is minimal and they, sadly enough, are often concerned only with the fact that a paper has been published rather than its content.

  15. Accelerating scientific publication in biology

    PubMed Central

    Vale, Ronald D.

    2015-01-01

    Scientific publications enable results and ideas to be transmitted throughout the scientific community. The number and type of journal publications also have become the primary criteria used in evaluating career advancement. Our analysis suggests that publication practices have changed considerably in the life sciences over the past 30 years. More experimental data are now required for publication, and the average time required for graduate students to publish their first paper has increased and is approaching the desirable duration of PhD training. Because publication is generally a requirement for career progression, schemes to reduce the time of graduate student and postdoctoral training may be difficult to implement without also considering new mechanisms for accelerating communication of their work. The increasing time to publication also delays potential catalytic effects that ensue when many scientists have access to new information. The time has come for life scientists, funding agencies, and publishers to discuss how to communicate new findings in a way that best serves the interests of the public and the scientific community. PMID:26508643

  16. User Facilities of the Office of Basic Energy Sciences: A National Resource for Scientific Research

    SciTech Connect

    2009-01-01

    The BES user facilities provide open access to specialized instrumentation and expertise that enable scientific users from universities, national laboratories, and industry to carry out experiments and develop theories that could not be done at their home institutions. These forefront research facilities require resource commitments well beyond the scope of any non-government institution and open up otherwise inaccessible facets of Nature to scientific inquiry. For approved, peer-reviewed projects, instrument time is available without charge to researchers who intend to publish their results in the open literature. These large-scale user facilities have made significant contributions to various scientific fields, including chemistry, physics, geology, materials science, environmental science, biology, and biomedical science. Over 16,000 scientists and engineers.pdf file (27KB) conduct experiments at BES user facilities annually. Thousands of other researchers collaborate with these users and analyze the data measured at the facilities to publish new scientific findings in peer-reviewed journals.

  17. Russian Scientific Project: "The Moon - 2012+"

    NASA Astrophysics Data System (ADS)

    Gusev, A.; Petrova, N.

    2006-08-01

    The realization of the modern long-time programs of comprehensive investigation of the Moon in the framework: "SMART-1" (ESA, 2003+), "SELENE" (JAXA, 2007), "Chandrayaan" (India, 2007), "CHANG'E-I" (CNSA, 2007), "LRO" (NASA, 2008), and "Luna Glob" (Russia, 2012) are aimed at obtaining of broad information about lunar gravity field, precision position in the inertial coordinate system, geometrical and dynamical figure and lunar interior: qualitative parameter Q, Love number k[2], core's radius R[c], core's density etc. Russian scientific project "The Moon - 2012+" is directed on the decision of fundamental problems of celestial mechanics, selenodesy and geophysics of the Moon connected to carrying out of complex theoretical researches and computer modelling: 1. Spin-orbital long-time evolution and physical librations the multilayered Moon: ?) construction of the analytical theory of rotation of the two/ three-layer Moon and reception on its basis of physical libration tables for their application at processing precision supervisions; construction of a lunar annual book. b) The analysis of spin-orbital evolution of the early Moon, an estimation of internal energy dissipation, modelling of the long-term mechanism of maintenance free librations the Moon. 2. Geodynamics of a lunar core: the analysis of differentiation of a lunar core, detailed elaboration of plume-tectonics of a mantle and a core of the early Moon, evolution of a boundary layer a core - mantle, reconstruction of gravitational and viscous - mechanical interaction of a lunar core and a mantle, resonant dissipation of internal energy, calculation free and forced nutations a lunar core, free fluctuations of system a core - mantle. 3. Selenodesy of lunar far - side: the decision of a return problem lunar gravimetry, construction of geodynamic model of a lunar crust, a mantle and a core, border Moho, reconstruction initial mascons on the Moon, creation precision topographical and gravitational models of the

  18. Annual Research Briefs, 1990

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The 1990 annual progress reports of the Research Fellows and students of the Center for Turbulent Research (CTR) are included. It is intended primarily as a contractor report to NASA, Ames Research Center. In addition, numerous CTR Manuscript Reports were published last year. The purpose of the CTR Manuscript Series is to expedite the dissemination of research results by the CTR staff. The CTR is devoted to the fundamental study of turbulent flow; its objectives are to produce advances in physical understanding of turbulence, in turbulence modeling and simulation, and in turbulence control.

  19. Nuclear Medicine Annual, 1989

    SciTech Connect

    Freeman, L.M.; Weissmann, H.S.

    1989-01-01

    Among the highlights of Nuclear Medicine Annual, 1989 are a status report on the thyroid scan in clinical practice, a review of functional and structural brain imaging in dementia, an update on radionuclide renal imaging in children, and an article outlining a quality assurance program for SPECT instrumentation. Also included are discussions on current concepts in osseous sports and stress injury scintigraphy and on correlative magnetic resonance and radionuclide imaging of bone. Other contributors assess the role of nuclear medicine in clinical decision making and examine medicolegal and regulatory aspects of nuclear medicine.

  20. Ultrasound Annual, 1983

    SciTech Connect

    Sanders, R.C.; Hill, M.C.

    1983-01-01

    The 1983 edition of Ultrasound Annual features a state-of-the-art assessment of real-time ultrasound technology and a look at improvements in real-time equipment. Chapters discuss important new obstetric applications of ultrasound in measuring fetal umbilical vein blood flow and monitoring ovarian follicular development in vivo and in vitro fertilization. Other topics covered include transrectal prostate ultrasound using a linear array system; ultrasound of the common bile duct; ultrasound in tropical diseases; prenatal diagnosis of craniospinal anomalies; scrotal ultrasonography; opthalmic ultrasonography; and sonography of the upper abdominal venous system.

  1. Annual Energy Review 2010

    SciTech Connect

    2011-10-01

    This twenty-ninth edition of the Annual Energy Review (AER) presents the U.S. Energy Information Administration’s (EIA) most comprehensive look at integrated energy statistics. The summary statistics on the Nation’s energy production, consumption, trade, stocks, and prices cover all major energy commodities and all energy-consuming sectors of the U.S. economy from 1949 through 2010. The AER is EIA’s historical record of energy statistics and, because the coverage spans six decades, the statistics in this report are well-suited to long-term trend analysis.

  2. International energy annual 1995

    SciTech Connect

    1996-12-01

    The International Energy Annual presents information and trends on world energy production and consumption for petroleum, natural gas, coal, and electricity. Production and consumption data are reported in standard units as well as British thermal units (Btu). Trade and reserves are shown for petroleum, natural gas, and coal. Data are provided on crude oil refining capacity and electricity installed capacity by type. Prices are included for selected crude oils and for refined petroleum products in selected countries. Population and Gross Domestic Product data are also provided.

  3. Annual Energy Review 2001

    SciTech Connect

    Seiferlein, Katherine E.

    2002-11-01

    The Annual Energy Review (AER) is a statistical history of energy activities in the United States. It documents trends and milestones in U.S. energy production, trade, storage, pricing, and consumption. Each new year of data that is added to the time series—which now reach into 7 decades—extends the story of how Americans have acquired and used energy. It is a story of continual change as the Nation's economy grew, energy requirements expanded, resource availability shifted, and interdependencies developed among nations.

  4. NPL 1999 Annual Report

    SciTech Connect

    2000-01-01

    OAK-B135 NPL 1999 Annual Report. The Nuclear Physics Laboratory at the University of Washington in Seattle pursues a broad program of nuclear physics research. Research activities are conducted locally and at remote sites. The current program includes ''in-house'' research on nuclear collisions using the local tandem Van de Graaff and superconducting linac accelerators as well as local and remote non-accelerator research on fundamental symmetries and weak interactions and user-mode research on relativistic heavy ions at large accelerator facilities around the world.

  5. Annual research briefs, 1989

    NASA Technical Reports Server (NTRS)

    Spinks, Debra (Compiler)

    1990-01-01

    This report contains the 1989 annual progress reports of the Research Fellows of the Center for Turbulence Research. It is intended as a year end report to NASA, Ames Research Center which supports this group through core funding and by making available physical and intellectual resources. The Center for Turbulence Research is devoted to the fundamental study of turbulent flows; its objectives are to simulate advances in the physical understanding of turbulence, in turbulence modeling and simulation, and in turbulence control. The reports appearing in the following pages are grouped in the general areas of modeling, experimental research, theory, simulation and numerical methods, and compressible and reacting flows.

  6. Renewable energy annual 1996

    SciTech Connect

    1997-03-01

    This report presents summary data on renewable energy consumption, the status of each of the primary renewable technologies, a profile of each of the associated industries, an analysis of topical issues related to renewable energy, and information on renewable energy projects worldwide. It is the second in a series of annual reports on renewable energy. The renewable energy resources included in the report are biomass (wood and ethanol); municipal solid waste, including waste-to-energy and landfill gas; geothermal; wind; and solar energy, including solar thermal and photovoltaic. The report also includes various appendices and a glossary.

  7. Annual report to Congress

    SciTech Connect

    1992-03-01

    This is the eighth annual report submitted by the Office of Civilian Radioactive Waste Management (OCRWM) to Congress. It covers activities and expenditures during Fiscal Year 1991, which ended September 30, 1991. Chapter 1 of this report describes OCRWM`s mission and objectives. Chapters 2 through 8 cover the following topics: earning public trust and confidence; geological disposal; monitored retrieval storage; transportation; systems integration and regulatory compliance; international programs; and program management. Financial statements for the Nuclear Waste Fund are presented in Chapter 9.

  8. Laser Science & Technology Program Annual Report - 2000

    SciTech Connect

    Chen, H-L

    2001-03-20

    The Laser Science and Technology (LS&T) Program Annual Report 2001 provides documentation of the achievements of the LLNL LS&T Program during the April 2001 to March 2002 period using three formats: (1) an Overview that is a narrative summary of important results for the year; (2) brief summaries of research and development activity highlights within the four Program elements: Advanced Lasers and Components (AL&C), Laser Optics and Materials (LO&M), Short Pulse Laser Applications and Technologies (SPLAT), and High-Energy Laser System and Tests (HELST); and (3) a compilation of selected articles and technical reports published in reputable scientific or technology journals in this period. All three elements (Annual Overview, Activity Highlights, and Technical Reports) are also on the Web: http://laser.llnl.gov/lasers/pubs/icfq.html. The underlying mission for the LS&T Program is to develop advanced lasers, optics, and materials technologies and applications to solve problems and create new capabilities of importance to the Laboratory and the nation. This mission statement has been our guide for defining work appropriate for our Program. A major new focus of LS&T beginning this past year has been the development of high peak power short-pulse capability for the National Ignition Facility (NIF). LS&T is committed to this activity.

  9. 2006 Annual Merit Review Proceedings

    SciTech Connect

    2009-01-18

    Each year hydrogen and fuel cell projects funded by DOE's Hydrogen Program are reviewed for their merit during an Annual Merit Review and Peer Evaluation Meeting. The 2006 Annual Merit Review, held May 16-19, 2006 in Arlington, Va., showcased approximately 250 projects. Principal investigators presented their project status and results in oral and poster presentations, which are available in the 2006 Annual Merit Review Proceedings. A panel of more than 150 community experts peer reviewed two-t

  10. Annual Energy Review 2009

    SciTech Connect

    Fichman, Barbara T.

    2010-08-01

    The Annual Energy Review (AER) is the U.S. Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, and international energy; financial and environment indicators; and data unit conversions. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding the content of the AER and other EIA publications.

  11. Annual Energy Review 2011

    SciTech Connect

    Fichman, Barbara T.

    2012-09-01

    The Annual Energy Review (AER) is the U.S. Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are statistics on total energy production, consumption, trade, and energy prices; overviews of petroleum, natural gas, coal, electricity, nuclear energy, and renewable energy; financial and environment indicators; and data unit conversions. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding the content of the AER and other EIA publications.

  12. Annual Energy Review 2005

    SciTech Connect

    Seiferlein, Katherine E.

    2006-07-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

  13. Annual Energy Review 2004

    SciTech Connect

    Seiferlein, Katherine E.

    2005-08-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

  14. Annual Energy Review 2006

    SciTech Connect

    Seiferlein, Katherine E.

    2007-06-01

    The Annual Energy Review (AER) is the Energy Information Administration's (EIA) primary report of annual historical energy statistics. For many series, data begin with the year 1949. Included are data on total energy production, consumption, and trade; overviews of petroleum, natural gas, coal, electricity, nuclear energy, renewable energy, international energy, as well as financial and environment indicators; and data unit conversion tables. Publication of this report is required under Public Law 95–91 (Department of Energy Organization Act), Section 205(c), and is in keeping with responsibilities given to the EIA under Section 205(a)(2), which states: “The Administrator shall be responsible for carrying out a central, comprehensive, and unified energy data and information program which will collect, evaluate, assemble, analyze, and disseminate data and information....” The AER is intended for use by Members of Congress, Federal and State agencies, energy analysts, and the general public. EIA welcomes suggestions from readers regarding data series in the AER and in other EIA publications.

  15. Electric power annual 1992

    SciTech Connect

    Not Available

    1994-01-06

    The Electric Power Annual presents a summary of electric utility statistics at national, regional and State levels. The objective of the publication is to provide industry decisionmakers, government policymakers, analysts and the general public with historical data that may be used in understanding US electricity markets. The Electric Power Annual is prepared by the Survey Management Division; Office of Coal, Nuclear, Electric and Alternate Fuels; Energy Information Administration (EIA); US Department of Energy. ``The US Electric Power Industry at a Glance`` section presents a profile of the electric power industry ownership and performance, and a review of key statistics for the year. Subsequent sections present data on generating capability, including proposed capability additions; net generation; fossil-fuel statistics; retail sales; revenue; financial statistics; environmental statistics; electric power transactions; demand-side management; and nonutility power producers. In addition, the appendices provide supplemental data on major disturbances and unusual occurrences in US electricity power systems. Each section contains related text and tables and refers the reader to the appropriate publication that contains more detailed data on the subject matter. Monetary values in this publication are expressed in nominal terms.

  16. Annual Energy Review 1993

    SciTech Connect

    Not Available

    1994-07-14

    This twelfth edition of the Annual Energy Review (AER) presents the Energy Information Administration`s historical energy statistics. For most series, statistics are given for every year from 1949 through 1993. Because coverage spans four and a half decades, the statistics in this report are well-suited to long-term trend analyses. The AER is comprehensive. It covers all major energy activities, including consumption, production, trade, stocks, and prices, for all major energy commodities, including fossil fuels and electricity. The AER also presents Energy Information Administration (EIA) statistics on some renewable energy sources. EIA estimates that its consumption series include about half of the renewable energy used in the United States. For a more complete discussion of EIA`s renewables data, see p. xix, ``Introducing Expanded Coverage of Renewable Energy Data Into the Historical Consumption Series.`` Copies of the 1993 edition of the Annual Energy Review may be obtained by using the order form in the back of this publication. Most of the data in the 1993 edition also are available on personal computer diskette. For more information about the diskettes, see the back of this publication. In addition, the data are available as part of the National Economic, Social, and Environmental Data Bank on a CD-ROM. For more information about the data bank, contact the US Department of Commerce Economics and Statistics Administration, on 202-482-1986.

  17. Symposium Scores Misuse of Scientific Data

    ERIC Educational Resources Information Center

    Krieger, James H.

    1975-01-01

    Presents examples of misuse of scientific data in the areas of eutrophication, food advertising, and public health. Outlines various ways in which individual scientists can act to ensure the proper use of scientific data. (GS)

  18. The Dogma of "The" Scientific Method.

    ERIC Educational Resources Information Center

    Wivagg, Dan; Allchin, Douglas

    2002-01-01

    Points out major problems with the scientific method as a model for learning about methodology in science and suggests teaching about the scientists' toolbox to remedy problems with the conventional scientific method. (KHR)

  19. Spacelab program's scientific benefits to mankind.

    PubMed

    Craft, H G; Marmann, R A

    1994-10-01

    This paper describes the Spacelab program's scientific accomplishments during the past 10 years, highlighting major scientific accomplishments. An overview of Spacelab systems performance, significant issues, and utilization and operations activities applicable to the space station era is presented. PMID:11540745

  20. Scientific Workflow Management in Proteomics

    PubMed Central

    de Bruin, Jeroen S.; Deelder, André M.; Palmblad, Magnus

    2012-01-01

    Data processing in proteomics can be a challenging endeavor, requiring extensive knowledge of many different software packages, all with different algorithms, data format requirements, and user interfaces. In this article we describe the integration of a number of existing programs and tools in Taverna Workbench, a scientific workflow manager currently being developed in the bioinformatics community. We demonstrate how a workflow manager provides a single, visually clear and intuitive interface to complex data analysis tasks in proteomics, from raw mass spectrometry data to protein identifications and beyond. PMID:22411703

  1. PREFACE: Scientific Organising Committee Information

    NASA Astrophysics Data System (ADS)

    2015-06-01

    Edited by: Oliver Roberts Lorraine Hanlon Sheila McBreen Local Organising Committee: Oliver Roberts (Chair) Antonio Martin-Carrillo Lorraine Hanlon Sheila McBreen Alexey Uliyanov David Murphy Sinéad Hales Scientific Organising Committee:: Sheila McBreen, (UCD, Ireland) (Chair) Franco Camera (INFN-Milano, Italy) Nerine Cherepy (LLNL, USA) Jarek Glodo (RMD, USA) Lorraine Hanlon (UCD, Ireland) Paul Lecoq (CERN, Switzerland) Julie McEnery (NASA, USA) Oliver Roberts (UCD, Ireland) Anant Setlur, (GE, USA) Brian Shortt, (ESA, the Netherlands) Kenneth Stanton (UCD, Ireland)

  2. Scientific Investigation with the SJCSI

    NASA Astrophysics Data System (ADS)

    Berbey, E.; Delpeyroux, G.; Douay, E.; Juchereau, C.; Garavet, O.

    2012-04-01

    Scientific Investigation with the SJCSI (Saint Jean* Crime Scene Investigation) Our work, which we have been teaching for 3 years, consists of a scientific investigation. We create a case from A to Z and then our students (15 to 16 years old) are meant to collect samples and clues from a reconstituted crime scene and then have to catch the culprit thanks to laboratory tests crossing four subjects: Physics and Chemistry, Biology, Math and English. I'm a biology teacher and I work with 3 other teachers in my school. The objectives of these activities are: • Make sciences more attractive by putting them into a context of crime investigation. • Use science techniques to find a culprit or to clear a suspect. • To acquire scientific knowledge. • Realize that the different scientific subjects complement each other to carry out a survey. • Use English language and improve it. The investigation consists of doing experiments after collecting different samples and clues on the crime scene. Examples of Biology experimentation: • Detecting the origin of the blood samples found on the crime scene. Students observe blood samples with a microscope and compare the characteristics to those of human blood found on the web. They discover that blood samples found aren't human blood because the red cells have a nucleus. By using the information given in the scenario, they discover that blood sample belongs to the parrot of a suspect. Students, also take a photo of their microscopic preparations, add title and caption and so they learn the cell's structure and the characteristics of blood cells. • In another case, students have to study the blood sample found under the victims fingernails. They observe blood preparation and compare it to the blood of a suspect who has a genetic disease: drepanocytosis. So, they discover the characteristics of blood cells by comparing them to sickle cells. • DNA electrophoresis to identify DNA found, for example, on the gun. • Blood type

  3. Scientific investigations of atmospheric processes

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Research was performed in atmospheric, dynamical, and thermodynamical processes and in other disciplines necessary to accomplish the following tasks: develop procedures for combining generalized radiative transfer codes with dynamic atmospheric model codes; perform diagnostic analysis of atmospheric processes to gain a better understanding of the evolution and development of mesoscale circulation systems and their precipitation structures; and to develop algorithms and software necessary to graphically display diagnostic sets on the MSFC McIDAS and EADS to facilitate scientific study and sensor capability evaluation. Research activities during this reporting period are detailed.

  4. Scientific Report (2002-2004)

    SciTech Connect

    Bedros Afeyan

    2004-05-11

    OAK-B135 An overview of our work as well as two recent publications are contained in this scientific report. The work reported here revolves around the discovery of new coherent nonlinear kinetic waves in laser produced plasmas, we call KEEN waves (kinetic, electrostatic electron nonlinear waves), and optical mixing experiments on the Imega laser system at LLE with blue-green light for the exploration of ways to suppress parametric instabilities in long scale length, long pulsewidth laser-plasmas such as those which will be found on NIF or LMJ.

  5. Surgical Skills Beyond Scientific Management.

    PubMed

    Whitfield, Nicholas

    2015-07-01

    During the Great War, the French surgeon Alexis Carrel, in collaboration with the English chemist Henry Dakin, devised an antiseptic treatment for infected wounds. This paper focuses on Carrel's attempt to standardise knowledge of infected wounds and their treatment, and looks closely at the vision of surgical skill he espoused and its difference from those associated with the doctrines of scientific management. Examining contemporary claims that the Carrel-Dakin method increased rather than diminished demands on surgical work, this paper further shows how debates about antiseptic wound treatment opened up a critical space for considering the nature of skill as a vital dynamic in surgical innovation and practice. PMID:26090737

  6. Surgical Skills Beyond Scientific Management

    PubMed Central

    Whitfield, Nicholas

    2015-01-01

    During the Great War, the French surgeon Alexis Carrel, in collaboration with the English chemist Henry Dakin, devised an antiseptic treatment for infected wounds. This paper focuses on Carrel’s attempt to standardise knowledge of infected wounds and their treatment, and looks closely at the vision of surgical skill he espoused and its difference from those associated with the doctrines of scientific management. Examining contemporary claims that the Carrel–Dakin method increased rather than diminished demands on surgical work, this paper further shows how debates about antiseptic wound treatment opened up a critical space for considering the nature of skill as a vital dynamic in surgical innovation and practice. PMID:26090737

  7. 2009 ALCF annual report.

    SciTech Connect

    Beckman, P.; Martin, D.; Drugan, C.

    2010-11-23

    This year the Argonne Leadership Computing Facility (ALCF) delivered nearly 900 million core hours of science. The research conducted at their leadership class facility touched our lives in both minute and massive ways - whether it was studying the catalytic properties of gold nanoparticles, predicting protein structures, or unearthing the secrets of exploding stars. The authors remained true to their vision to act as the forefront computational center in extending science frontiers by solving pressing problems for our nation. Our success in this endeavor was due mainly to the Department of Energy's (DOE) INCITE (Innovative and Novel Computational Impact on Theory and Experiment) program. The program awards significant amounts of computing time to computationally intensive, unclassified research projects that can make high-impact scientific advances. This year, DOE allocated 400 million hours of time to 28 research projects at the ALCF. Scientists from around the world conducted the research, representing such esteemed institutions as the Princeton Plasma Physics Laboratory, National Institute of Standards and Technology, and European Center for Research and Advanced Training in Scientific Computation. Argonne also provided Director's Discretionary allocations for research challenges, addressing such issues as reducing aerodynamic noise, critical for next-generation 'green' energy systems. Intrepid - the ALCF's 557-teraflops IBM Blue/Gene P supercomputer - enabled astounding scientific solutions and discoveries. Intrepid went into full production five months ahead of schedule. As a result, the ALCF nearly doubled the days of production computing available to the DOE Office of Science, INCITE awardees, and Argonne projects. One of the fastest supercomputers in the world for open science, the energy-efficient system uses about one-third as much electricity as a machine of comparable size built with more conventional parts. In October 2009, President Barack Obama

  8. Annual Energy Review 1999

    SciTech Connect

    Seiferlein, Katherine E.

    2000-07-01

    A generation ago the Ford Foundation convened a group of experts to explore and assess the Nation’s energy future, and published their conclusions in A Time To Choose: America’s Energy Future (Cambridge, MA: Ballinger, 1974). The Energy Policy Project developed scenarios of U.S. potential energy use in 1985 and 2000. Now, with 1985 well behind us and 2000 nearly on the record books, it may be of interest to take a look back to see what actually happened and consider what it means for our future. The study group sketched three primary scenarios with differing assumptions about the growth of energy use. The Historical Growth scenario assumed that U.S. energy consumption would continue to expand by 3.4 percent per year, the average rate from 1950 to 1970. This scenario assumed no intentional efforts to change the pattern of consumption, only efforts to encourage development of our energy supply. The Technical Fix scenario anticipated a “conscious national effort to use energy more efficiently through engineering know-how." The Zero Energy Growth scenario, while not clamping down on the economy or calling for austerity, incorporated the Technical Fix efficiencies plus additional efficiencies. This third path anticipated that economic growth would depend less on energy-intensive industries and more on those that require less energy, i.e., the service sector. In 2000, total energy consumption was projected to be 187 quadrillion British thermal units (Btu) in the Historical Growth case, 124 quadrillion Btu in the Technical Fix case, and 100 quadrillion Btu in the Zero Energy Growth case. The Annual Energy Review 1999 reports a preliminary total consumption for 1999 of 97 quadrillion Btu (see Table 1.1), and the Energy Information Administration’s Short-Term Energy Outlook (April 2000) forecasts total energy consumption of 98 quadrillion Btu in 2000. What energy consumption path did the United States actually travel to get from 1974, when the scenarios were drawn

  9. The Organization of Reports of Scientific Experiments.

    ERIC Educational Resources Information Center

    Sawyer, Thomas M.

    Beginning teachers of scientific technical writing often have little background knowledge in the sciences; thus, they may encounter difficulty in dealing with technical reports. To achieve clear explanations of the effects of scientific experiments, scientific writers need to know the following general principles: (1) the function of all the…

  10. Scientific Communication and the Nature of Science

    ERIC Educational Resources Information Center

    Nielsen, Kristian H.

    2013-01-01

    Communication is an important part of scientific practice and, arguably, may be seen as constitutive to scientific knowledge. Yet, often scientific communication gets cursory treatment in science studies as well as in science education. In Nature of Science (NOS), for example, communication is rarely mentioned explicitly, even though, as will be…

  11. 76 FR 14375 - Census Scientific Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... Bureau of the Census Census Scientific Advisory Committee AGENCY: Bureau of the Census, U.S. Department...) is giving notice of a meeting of the Census Scientific Advisory Committee (C-SAC). The Committee will... appointed by the Director, U.S. Census Bureau. The Committee provides scientific and technical expertise,...

  12. 78 FR 49725 - Census Scientific Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ... Bureau of the Census Census Scientific Advisory Committee AGENCY: Bureau of the Census, Department of... giving notice of a meeting of the Census Scientific Advisory Committee (C-SAC). The C-SAC will meet in a... adjustments. DATES: September 19 and 20, 2013. On September 19, the Census Scientific Advisory...

  13. 77 FR 52680 - Census Scientific Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... Bureau of the Census Census Scientific Advisory Committee AGENCY: Bureau of the Census, Department of... giving notice of a meeting of the Census Scientific Advisory Committee (C-SAC). The Committee will...-SAC are appointed by the Director, U.S. Census Bureau. The Committee provides scientific and...

  14. 75 FR 16078 - Census Scientific Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... Bureau of the Census Census Scientific Advisory Committee AGENCY: Bureau of the Census, Department of... giving notice of a meeting of the Census Scientific Advisory Committee (C-SAC). The Committee will... appointed by the Director, U.S. Census Bureau. The Committee provides scientific and technical expertise,...

  15. 77 FR 12799 - Census Scientific Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... Bureau of the Census Census Scientific Advisory Committee AGENCY: Bureau of the Census, Department of... giving notice of a meeting of the Census Scientific Advisory Committee (C-SAC). The Committee will... appointed by the Director, U.S. Census Bureau. The Committee provides scientific and technical expertise,...

  16. 50 CFR 660.519 - Scientific observers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Scientific observers. 660.519 Section 660... § 660.519 Scientific observers. All fishing vessels operating in the coastal pelagic species fishery... collect scientific data. An observer program will be considered only for circumstances where other...

  17. 50 CFR 660.519 - Scientific observers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Scientific observers. 660.519 Section 660... § 660.519 Scientific observers. All fishing vessels operating in the coastal pelagic species fishery... collect scientific data. An observer program will be considered only for circumstances where other...

  18. Scientific Activities of Nonprofit Institutions 1966.

    ERIC Educational Resources Information Center

    Biggar, Ronald S., Jr.; And Others

    This report summarizes the results of the National Science Foundation's survey of scientific activities of independent nonprofit organizations in 1966. Information is included on expenditures for research, development, and scientific and technical information activities and on the employment of scientific personnel associated with these…

  19. The Influence of CASE on Scientific Creativity.

    ERIC Educational Resources Information Center

    Lin, Chongde; Hu, Weiping; Adey, Philip; Shen, Jiliang

    2003-01-01

    Describes a study of the influence of the Cognitive Acceleration through Science Education (CASE) program on the scientific creativity of secondary school students. Scientific creativity is measured by the Scientific Creativity Test for Secondary School Students. Results indicate that the program did promote the overall development of scientific…

  20. 50 CFR 14.24 - Scientific specimens.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 1 2013-10-01 2013-10-01 false Scientific specimens. 14.24 Section 14.24....24 Scientific specimens. Except for wildlife requiring a permit pursuant to parts 16, 17, 18, 21, 22 or 23 of this subchapter, dead, preserved, dried, or embedded scientific specimens or parts...

  1. 50 CFR 14.24 - Scientific specimens.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 1 2014-10-01 2014-10-01 false Scientific specimens. 14.24 Section 14.24....24 Scientific specimens. Except for wildlife requiring a permit pursuant to parts 16, 17, 18, 21, 22 or 23 of this subchapter, dead, preserved, dried, or embedded scientific specimens or parts...

  2. 50 CFR 14.24 - Scientific specimens.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 1 2011-10-01 2011-10-01 false Scientific specimens. 14.24 Section 14.24....24 Scientific specimens. Except for wildlife requiring a permit pursuant to parts 16, 17, 18, 21, 22 or 23 of this subchapter, dead, preserved, dried, or embedded scientific specimens or parts...

  3. 50 CFR 14.24 - Scientific specimens.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 1 2012-10-01 2012-10-01 false Scientific specimens. 14.24 Section 14.24....24 Scientific specimens. Except for wildlife requiring a permit pursuant to parts 16, 17, 18, 21, 22 or 23 of this subchapter, dead, preserved, dried, or embedded scientific specimens or parts...

  4. 50 CFR 14.24 - Scientific specimens.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Scientific specimens. 14.24 Section 14.24....24 Scientific specimens. Except for wildlife requiring a permit pursuant to parts 16, 17, 18, 21, 22 or 23 of this subchapter, dead, preserved, dried, or embedded scientific specimens or parts...

  5. 50 CFR 660.519 - Scientific observers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Scientific observers. 660.519 Section 660... § 660.519 Scientific observers. All fishing vessels operating in the coastal pelagic species fishery... collect scientific data. An observer program will be considered only for circumstances where other...

  6. 50 CFR 660.519 - Scientific observers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Scientific observers. 660.519 Section 660... § 660.519 Scientific observers. All fishing vessels operating in the coastal pelagic species fishery... collect scientific data. An observer program will be considered only for circumstances where other...

  7. 50 CFR 660.519 - Scientific observers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Scientific observers. 660.519 Section 660... § 660.519 Scientific observers. All fishing vessels operating in the coastal pelagic species fishery... collect scientific data. An observer program will be considered only for circumstances where other...

  8. [New guidelines on good scientific practice].

    PubMed

    Nielsen, Ole Haagen

    2009-05-25

    In 2009 the Danish Committees on Scientific Dishonesty released their new guidelines on good scientific practice (i.e. responsible conduct of research) with a particular focus on healthcare. These guidelines are intended to help Danish researchers avoid any discreditability of their scientific work, and especially to improve the general standard of their research. PMID:19486614

  9. Physical Science Experiments for Scientific Glassblowing Technicians.

    ERIC Educational Resources Information Center

    Tillis, Samuel E.; Donaghay, Herbert C.

    The twenty experiments in this text have been designed to give the scientific glassblowing technician the opportunity to use scientific glass apparatus in the study of physical science. Primary emphasis of these experiments is on the practical application of the physical science program as a working tool for the scientific glassblowing technician.…

  10. The Gaia scientific exploitation networks

    NASA Astrophysics Data System (ADS)

    Figueras, F.; Jordi, C.

    2015-05-01

    On July 2014 the Gaia satellite, placed at L2 since January 2014, finished their commissioning phase and started collecting high accurate scientific data. New and more realistic estimations of the astrometric, photometric and spectroscopic accuracy expected after five years mission operation (2014-2019) have been recently published in the Gaia Science Performance Web page. Here we present the coordination efforts and the activities being conducted through the two GREAT (Gaia Research for European Astronomy Training) European Networks, the GREAT-ESF, a programme supported by the European Science Foundation (2010-2015), and the GREAT-ITN network, from the European Union's Seventh Framework Programme (2011-2015). The main research theme of these networks is to unravel the origin and history of our home galaxy. Emphasis is placed on the research projects being conducted by the Spanish Researchers through these networks, well coordinated by the Red Española de Explotación Científica de Gaia (REG network, with more than 140 participants). Members of the REG play an important role on the collection of complementary spectroscopic data from ground based telescopes, on the development of new tools for an optimal scientific exploitation of Gaia data and on the preparation task to create the Gaia archive.

  11. Darwin and the scientific method

    PubMed Central

    Ayala, Francisco J.

    2009-01-01

    There is a contradiction between Darwin's methodology and how he described it for public consumption. Darwin claimed that he proceeded “on true Baconian [inductive] principles and without any theory collected facts on a wholesale scale.” He also wrote, “How odd it is that anyone should not see that all observation must be for or against some view if it is to be of any service!” The scientific method includes 2 episodes. The first consists of formulating hypotheses; the second consists of experimentally testing them. What differentiates science from other knowledge is the second episode: subjecting hypotheses to empirical testing by observing whether or not predictions derived from a hypothesis are the case in relevant observations and experiments. A hypothesis is scientific only if it is consistent with some but not other possible states of affairs not yet observed, so that it is subject to the possibility of falsification by reference to experience. Darwin occupies an exalted place in the history of Western thought, deservedly receiving credit for the theory of evolution. In The Origin of Species, he laid out the evidence demonstrating the evolution of organisms. More important yet is that he discovered natural selection, the process that accounts for the adaptations of organisms and their complexity and diversification. Natural selection and other causal processes of evolution are investigated by formulating and testing hypotheses. Darwin advanced hypotheses in multiple fields, including geology, plant morphology and physiology, psychology, and evolution, and subjected them to severe empirical tests. PMID:19528662

  12. [On freedom of scientific research].

    PubMed

    Folkers, G

    2013-07-01

    Debates about science and, more specifically, about scientific research quickly bring up the question about its freedom. Science is readily blamed for technological disasters or criticized for nursing fantasies of omnipotence and commercial gain. This prompts the call for a restriction of its freedom. At the same time, society's demands on science are enormous, to the effect that science and technology have acquired the status of a deus-ex-machina: they are expected to furnish short-term, affordable, and convenient solutions to a wide range of problems, including issues of health, transportation, food and, more generally, a comfortable life. What kind of freedom is required to meet these expectations? Who is in a position to grant it? What does freedom for science mean and how is it linked to responsibility? The paper examines the current situation of freedom in scientific research and of its restrictions, many of which are mentally or economically conditioned. It calls for the involvement of an informed, self-confident bourgeoisie in research decisions and for the educational measures this necessitates. Finally, it demands a greater appreciation of education (rather than training) as the basis of social trust, and the recognition of continuous education as a productive investment of time and a crucial element in the employment of social goods. PMID:23923630

  13. Representation of Serendipitous Scientific Data

    NASA Technical Reports Server (NTRS)

    James, Mark

    2006-01-01

    A computer program defines and implements an innovative kind of data structure than can be used for representing information derived from serendipitous discoveries made via collection of scientific data on long exploratory spacecraft missions. Data structures capable of collecting any kind of data can easily be implemented in advance, but the task of designing a fixed and efficient data structure suitable for processing raw data into useful information and taking advantage of serendipitous scientific discovery is becoming increasingly difficult as missions go deeper into space. The present software eases the task by enabling definition of arbitrarily complex data structures that can adapt at run time as raw data are transformed into other types of information. This software runs on a variety of computers, and can be distributed in either source code or binary code form. It must be run in conjunction with any one of a number of Lisp compilers that are available commercially or as shareware. It has no specific memory requirements and depends upon the other software with which it is used. This program is implemented as a library that is called by, and becomes folded into, the other software with which it is used.

  14. Darwin and the scientific method.

    PubMed

    Ayala, Francisco J

    2009-06-16

    There is a contradiction between Darwin's methodology and how he described it for public consumption. Darwin claimed that he proceeded "on true Baconian [inductive] principles and without any theory collected facts on a wholesale scale." He also wrote, "How odd it is that anyone should not see that all observation must be for or against some view if it is to be of any service!" The scientific method includes 2 episodes. The first consists of formulating hypotheses; the second consists of experimentally testing them. What differentiates science from other knowledge is the second episode: subjecting hypotheses to empirical testing by observing whether or not predictions derived from a hypothesis are the case in relevant observations and experiments. A hypothesis is scientific only if it is consistent with some but not other possible states of affairs not yet observed, so that it is subject to the possibility of falsification by reference to experience. Darwin occupies an exalted place in the history of Western thought, deservedly receiving credit for the theory of evolution. In The Origin of Species, he laid out the evidence demonstrating the evolution of organisms. More important yet is that he discovered natural selection, the process that accounts for the adaptations of organisms and their complexity and diversification. Natural selection and other causal processes of evolution are investigated by formulating and testing hypotheses. Darwin advanced hypotheses in multiple fields, including geology, plant morphology and physiology, psychology, and evolution, and subjected them to severe empirical tests. PMID:19528662

  15. Prioritizing Scientific Data for Transmission

    NASA Technical Reports Server (NTRS)

    Castano, Rebecca; Anderson, Robert; Estlin, Tara; DeCoste, Dennis; Gaines, Daniel; Mazzoni, Dominic; Fisher, Forest; Judd, Michele

    2004-01-01

    A software system has been developed for prioritizing newly acquired geological data onboard a planetary rover. The system has been designed to enable efficient use of limited communication resources by transmitting the data likely to have the most scientific value. This software operates onboard a rover by analyzing collected data, identifying potential scientific targets, and then using that information to prioritize data for transmission to Earth. Currently, the system is focused on the analysis of acquired images, although the general techniques are applicable to a wide range of data modalities. Image prioritization is performed using two main steps. In the first step, the software detects features of interest from each image. In its current application, the system is focused on visual properties of rocks. Thus, rocks are located in each image and rock properties, such as shape, texture, and albedo, are extracted from the identified rocks. In the second step, the features extracted from a group of images are used to prioritize the images using three different methods: (1) identification of key target signature (finding specific rock features the scientist has identified as important), (2) novelty detection (finding rocks we haven t seen before), and (3) representative rock sampling (finding the most average sample of each rock type). These methods use techniques such as K-means unsupervised clustering and a discrimination-based kernel classifier to rank images based on their interest level.

  16. Astrium spaceplane for scientific missions

    NASA Astrophysics Data System (ADS)

    Chavagnac, Christophe; Gai, Frédéric; Gharib, Thierry; Mora, Christophe

    2013-12-01

    Since years Novespace and Astrium are discussing mutual interest in cooperating together when considering Novespace well established capabilities and the ongoing development of the Astrium Spaceplane and its unique features. Indeed both companies are proposing service for non-public missions which require microgravity environment especially. It relies on assets of both parties: Novespace in operating 0-G aircraft platforms for the sake of the European scientific community for decades; Astrium and its Spaceplane currently in pre-development phase. Novespace and its Airbus A300 Zero-G exhibit a unique know-how in Europe for operating scientific payload on aeronautic platform(s). Moreover Astrium is preparing the development of a safe and passenger friendly Spaceplane, taking off and landing from a standard airport runway powered by turbofans and using a rocket engine of proven design to reach 100 km altitude. The paper details the joint service offered and the added value of the partnership of Novespace and Astrium for various end-users. In addition longer duration of on-board microgravity periods and ultra high altitude features of the Astrium Spaceplane mission expand the scope of possible non-public applications which includes e.g.: Earth system science and probing of uncharted layers of Earth atmosphere on a regular basis and in various locations worldwide; Spaceflight crew training.

  17. An Introduction to Scientific Masculinities.

    PubMed

    Milam, Erika Lorraine; Nye, Robert A

    2015-01-01

    This volume seeks to integrate gender analysis into the global history of science and medicine from the late Middle Ages to the present by focusing on masculinity, the part of the gender equation that has received the least attention from scholars. The premise of the volume is that social constructions of masculinity function simultaneously as foils for femininity and as methods of differentiating between "kinds" of men. In exploring scientific masculinities without taking the dominance of men and masculinity in the sciences for granted, we ask, What is masculinity and how does it operate in science? Our answers remind us that gender is at once an analytical category and a historical object. The essays are divided into three sections that in turn emphasize the importance of gender to the professionalization of scientific, technological, and medical practices, the spaces in which such labor is performed, and the ways that sex, gender, and sexual orientation are measured and serve as metaphors in society and culture. PMID:27066616

  18. MS PHD'S Professional Development Program: A Scientific Renaissance in Cyberspace

    NASA Astrophysics Data System (ADS)

    Powell, J. M.; Williamson, V. A.; Griess, C. A.; Pyrtle, A. J.

    2004-12-01

    This study is a component of a four-year investigation of MS PHD'S Professional Development Program's virtual community through the lenses of underrepresented minority students in Earth system science and engineering fields. In this presentation, the development, assessment and projected utilization of the ongoing study will be discussed. The overall goal of this study is to examine the effectiveness of virtual team building methods and understand how the development of a communal cyberinfrastructure acts as an integral part of the emergence of a Scientific Renaissance. The exemplar, Minorities Striving and Pursuing Higher Degrees of Success in Earth System Science (MS PHD'S), provides professional development experiences to facilitate the advancement of students of color achieving outstanding Earth system careers. Undergraduate and graduate students are supported through access to scientific conferences, mentorship and virtual community building. Framed by critical theory, this ethnographic exploration uses a mixed methods research design to record, observe, and analyze both the processes and products of the website, listserv and synchronous web-based dialogue. First, key findings of the formative evaluation and annual reports of the successfully implemented 2003 MS PHD'S Pilot Project are presented. These findings inform future evaluations of the use of technological resources and illustrate how this public space provides peer support and enriched research opportunities. Quantitative methods such as statistical analysis, academic and professional tracking and evaluative tools for scientific content and competency are complimented by qualitative methods that include observations, heuristic case studies and focus group interviews. The findings of this ongoing investigation will provide insight on how national organizations, higher education practitioners, community-based support systems and underrepresented minorities in the sciences promote diversity by developing

  19. Computation Directorate Annual Report 2003

    SciTech Connect

    Crawford, D L; McGraw, J R; Ashby, S F; McCoy, M G; Michels, T C; Eltgroth, P G

    2004-03-12

    Big computers are icons: symbols of the culture, and of the larger computing infrastructure that exists at Lawrence Livermore. Through the collective effort of Laboratory personnel, they enable scientific discovery and engineering development on an unprecedented scale. For more than three decades, the Computation Directorate has supplied the big computers that enable the science necessary for Laboratory missions and programs. Livermore supercomputing is uniquely mission driven. The high-fidelity weapon simulation capabilities essential to the Stockpile Stewardship Program compel major advances in weapons codes and science, compute power, and computational infrastructure. Computation's activities align with this vital mission of the Department of Energy. Increasingly, non-weapons Laboratory programs also rely on computer simulation. World-class achievements have been accomplished by LLNL specialists working in multi-disciplinary research and development teams. In these teams, Computation personnel employ a wide array of skills, from desktop support expertise, to complex applications development, to advanced research. Computation's skilled professionals make the Directorate the success that it has become. These individuals know the importance of the work they do and the many ways it contributes to Laboratory missions. They make appropriate and timely decisions that move the entire organization forward. They make Computation a leader in helping LLNL achieve its programmatic milestones. I dedicate this inaugural Annual Report to the people of Computation in recognition of their continuing contributions. I am proud that we perform our work securely and safely. Despite increased cyber attacks on our computing infrastructure from the Internet, advanced cyber security practices ensure that our computing environment remains secure. Through Integrated Safety Management (ISM) and diligent oversight, we address safety issues promptly and aggressively. The safety of our

  20. Petroleum marketing annual 1993

    SciTech Connect

    Not Available

    1995-01-01

    The Petroleum Marketing Annual (PMA) contains statistical data on a variety of crude oils and refined petroleum products. The publication provides statistics on crude oil costs and refined petroleum products sales for use by industry, government, private sector analysts, educational institutions, and consumers. Data on crude oil include the domestic first purchase price, the free-on-board (f.o.b.) and landed cost of imported crude oil, and the refiners acquisition cost of crude oil. Sales data for motor gasoline, distillates, residuals, aviation fuels, kerosene, and propane are presented. For this publication, all estimates have been recalculated since their earlier publication in the Petroleum Marketing Monthly (PMM). These calculations made use of additional data and corrections that were received after the PMM publication dates.