Pharmacological, neurochemical, and behavioral profile of JB-788, a new 5-HT1A agonist.

PubMed

Picard, M; Morisset, S; Cloix, J F; Bizot, J C; Guerin, M; Beneteau, V; Guillaumet, G; Hevor, T K

2010-09-01

A novel pyridine derivative, 8-{4-[(6-methoxy-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-3-ylmethyl)-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione hydrochloride, termed JB-788, was designed to selectively target 5-HT(1A) receptors. In the present study, the pharmacological profile of JB-788 was characterized in vitro using radioligands binding tests and in vivo using neurochemical and behavioural experiments. JB-788 bound tightly to human 5-HT(1A) receptor expressed in human embryonic kidney 293 (HEK-293) cells with a K(i) value of 0.8 nM. Its binding affinity is in the same range as that observed for the (+/-)8-OH-DPAT, a reference 5HT(1A) agonist compound. Notably, JB-788 only bound weakly to 5-HT(1B) or 5-HT(2A) receptors and moreover the drug displayed only weak or indetectable binding to muscarinic, alpha(2), beta(1) and beta(2) adrenergic receptors, or dopaminergic D(1) receptors. JB-788 was found to display substantial binding affinity for dopaminergic D(2) receptors and, to a lesser extend to alpha(1) adrenoreceptors. JB-788 dose-dependently decreased forskolin-induced cAMP accumulation in HEK cells expressing human 5-HT(1A), thus acting as a potent 5-HT(1A) receptor agonist (E(max.) 75%, EC(50) 3.5 nM). JB-788 did not exhibit any D(2) receptor agonism but progressively inhibited the effects of quinpirole, a D(2) receptor agonist, in the cAMP accumulation test with a K(i) value of 250 nM. JB-788 induced a weak change in cAMP levels in mouse brain but, like some antipsychotics, transiently increased glycogen contents in various brain regions. Behavioral effects were investigated in mice using the elevated plus-maze. JB-788 was found to increase the time duration spent by animals in anxiogenic situations. Locomotor hyperactivity induced by methamphetamine in mouse, a model of antipsychotic activity, was dose-dependently inhibited by JB-788. Altogether, these results suggest that JB-788 displays pharmacological properties, which could be of interest in the area

JB-9322, a new selective histamine H2-receptor antagonist with potent gastric mucosal protective properties.

PubMed

Palacios, B; Montero, M J; Sevilla, M A; Román, L S

1995-05-01

1. JB-9322 is a selective histamine H2-receptor antagonist with gastric antisecretory activity and mucosal protective properties. 2. The affinity of JB-9322 for the guinea-pig atria histamine H2-receptor was approximately 2 times greater than that of ranitidine. 3. In vivo, the ID50 value for the inhibition of gastric acid secretion in pylorus-ligated rats was 5.28 mg kg-1 intraperitoneally. JB-9322 also dose-dependently inhibited gastric juice volume and pepsin secretion. In gastric lumen-perfused rats, intravenous injection of JB-9322 dose-dependently reduced histamine-, pentagastrin- and carbachol-stimulated gastric acid secretion. 4. JB-9322 showed antiulcer activity against aspirin and indomethacin-induced gastric lesions and was more potent than ranitidine. 5. JB-9322 effectively inhibited macroscopic gastric haemorrhagic lesions induced by ethanol. Intraperitoneal injection was effective in preventing the lesions as well as oral treatment. The oral ID50 value for these lesions was 1.33 mg kg-1. By contrast, ranitidine (50 mg kg-1) failed to reduce these lesions. In addition, the protective effect of JB-9322 was independent of prostaglandin synthesis. 6. These results indicate that JB-9322 is a new antiulcer drug that exerts a potent cytoprotective effect in addition to its gastric antisecretory activity.

Dicke-model simulation via cavity-assisted Raman transitions

NASA Astrophysics Data System (ADS)

Zhang, Zhiqiang; Lee, Chern Hui; Kumar, Ravi; Arnold, K. J.; Masson, Stuart J.; Grimsmo, A. L.; Parkins, A. S.; Barrett, M. D.

2018-04-01

The Dicke model is of fundamental importance in quantum mechanics for understanding the collective behavior of atoms coupled to a single electromagnetic mode. Here, we demonstrate a Dicke-model simulation via cavity-assisted Raman transitions in a configuration using counterpropagating laser beams. The observations indicate that motional effects should be included to fully account for the results. These results are contrary to experiments using single-beam and copropagating configurations. We give a theoretical description that accounts for the beam geometries used in the experiments and indicates the potential role of motional effects. In particular, a model is given that highlights the influence of Doppler broadening on the observed phase-transition thresholds.

Interview with Dick Fish

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

An interview with Dick Fish of the Lawrence Berkeley Laboratory is presented. Mr. Fish's current research interests are discussed. These interests include the identification of trace metal non-porphyrin compounds in heavy crude petroleums. In particular, these interests include the identification of a class of nickel and vanadium compounds in the heavy crude petroleum from various geographical locations, e.g., the Boscan in Cerro Negro in Venezuela, Wilmington in California, and Prudhoe Bay in Alaska.

Entanglement detection in the vicinity of arbitrary Dicke states.

PubMed

Duan, L-M

2011-10-28

Dicke states represent a class of multipartite entangled states that can be generated experimentally with many applications in quantum information. We propose a method to experimentally detect genuine multipartite entanglement in the vicinity of arbitrary Dicke states. The detection scheme can be used to experimentally quantify the entanglement depth of many-body systems and is easy to implement as it requires measurement of only three collective spin operators. The detection criterion is strong as it heralds multipartite entanglement even in cases where the state fidelity goes down exponentially with the number of qubits.

Obituary: Henry Emil Kandrup, 1955-2003

NASA Astrophysics Data System (ADS)

Merritt, David; Gottesman, Stephen T.

2004-12-01

Henry Emil Kandrup died on 18 October 2003 at his home in Gainesville Florida. Henry was a theoretical astrophysicist specializing in the application of chaotic dynamics to stellar systems. At the time of his death, Henry was a Professor at the University of Florida where he had taught for 13 years. Henry was born in Manhasset, New York on July 24, 1955 and spent most of his childhood in Great Neck. His parents, Jytte and Fred, were immigrants from Denmark where his father had worked as a silver smith. Henry was a precocious child, skipping both third and fifth grades. With the help of Sidney Spivack, a professor of sociology at Columbia University, his parents enrolled Henry in the Brooks Preparatory School in Andover, Massachusetts. After graduating at age 16, Henry enrolled at Cornell, transferring to Princeton the following year. Henry's parents adored their only child and worked hard to provide him with intellectual opportunities. Henry became an accomplished musician (organ, piano, French horn) and linguist (English, Danish, German) and was a passionate devotee of opera and ballet. Henry received his PhD in 1980 from the University of Chicago, where his thesis advisor was James Ipser. He taught at Oakland University in Michigan and Syracuse University in New York before coming to the University of Florida in 1990. Henry was sui generis. He shunned conventionality in his personal appearance and in his public demeanor, and always chose forthrightness and candor over polite silence. But to those of us who knew Henry well, his bluntness was a reflection of his intellectual consistency. Henry always said exactly what he thought, both in his published work and his public presentations, and never compromised himself for the sake of appearances. Nothing that he said or wrote was less than fully thought out. Henry's PhD thesis was entitled "Stochastic Problems in Stellar Dynamics," and most of his subsequent research was in this field. Motion in stellar systems can be

Comment on the Jordan-Brands-Dicke universes

NASA Astrophysics Data System (ADS)

Lorenz-Petzold, D.

1987-06-01

It is shown that the recently obtained Jordan-Brans-Dicke solutions by Chauvet and Guzmán (1986) are either inconsistent, or only special power-law solutions derived previously by Lorenz-Petzold in various papers.

Physicochemical properties of polycyclic aromatic hydrocarbons: Aqueous solubilities, n-octanol/water partition coefficients, and Henry`s law constants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maagd, P.G.J. de; Opperhuizen, A.; Sijm, D.T.H.M.

Aqueous solubilities, n-octanol/water partition coefficients (K{sub ow}S), and Henry`s law constants were determined for a range of polycyclic aromatic hydrocarbons (PAHs) using a generator-column, slow-stirring, and gas-purge method, respectively. The currently obtained data were compared to available literature data. For seven of the PAHs no K{sub ow}S previously were determined with the slow-stirring method. For four of the PAHs the present study reports the first experimental Henry`s law constants. Relationships between subcooled liquid solubilities, K{sub ow}S, and Henry`s law constants as a function of molar volume are discussed. A consistent data set was obtained, for which an excellent correlation wasmore » found between subcooled liquid solubility and molar volume. A linear fit did not accurately describe the relationship between log K{sub ow} and molar volume. This is probably due to a decreasing solubility in n-octanol with increasing molar volume. Finally, a high correlation was found between Henry`s law constant and molar volume. The presently obtained dataset can be used to predict the fate and behavior of unsubstituted homocyclic PAHs.« less

Inflation and dark energy from the Brans-Dicke theory

NASA Astrophysics Data System (ADS)

Artymowski, Michał; Lalak, Zygmunt; Lewicki, Marek

2015-06-01

We consider the Brans-Dicke theory motivated by the f(R) = R + α Rn - β R2-n model to obtain a stable minimum of the Einstein frame scalar potential of the Brans-Dicke field. As a result we have obtained an inflationary scalar potential with non-zero value of residual vacuum energy, which may be a source of dark energy. In addition we discuss the probability of quantum tunnelling from the minimum of the potential. Our results can be easily consistent with PLANCK or BICEP2 data for appropriate choices of the value of n and ω.

Experimental entanglement of a six-photon symmetric Dicke state.

PubMed

Wieczorek, Witlef; Krischek, Roland; Kiesel, Nikolai; Michelberger, Patrick; Tóth, Géza; Weinfurter, Harald

2009-07-10

We report on the experimental observation and characterization of a six-photon entangled Dicke state. We obtain a fidelity as high as 0.654+/-0.024 and prove genuine six-photon entanglement by, amongst others, a two-setting witness yielding -0.422+/-0.148. This state has remarkable properties; e.g., it allows obtaining inequivalent entangled states of a lower qubit number via projective measurements, and it possesses a high entanglement persistency against qubit loss. We characterize the properties of the six-photon Dicke state experimentally by detecting and analyzing the entanglement of a variety of multipartite entangled states.

Antigravity in F( R) and Brans-Dicke theories

NASA Astrophysics Data System (ADS)

Oikonomou, V. K.; Karagiannakis, N.

2014-12-01

We study antigravity in F( R)-theory originating scalar-tensor theories and also in Brans-Dicke models without cosmological constant. For the F( R) theory case, we obtain the Jordan frame antigravity scalar-tensor theory by using a variant of the Lagrange multipliers method and we numerically study the time dependent effective gravitational constant. As we shall demonstrate in detail by using some viable F( R) models, although the initial F( R) models have no antigravity, their scalar-tensor counterpart theories might or not have antigravity, a fact mainly depending on the parameter that characterizes antigravity. Similar results hold true in the Brans-Dicke model, which we also studied numerically. In addition, regarding the Brans-Dicke model we also found some analytic cosmological solutions. Since antigravity is an unwanted feature in gravitational theories, our findings suggest that in the case of F( R) theories, antigravity does not occur in the real world described by the F( R) theory, but might occur in the Jordan frame scalar-tensor counterpart of the F( R) theory, and this happens under certain circumstances. The central goal of our study is to present all different cases in which antigravity might occur in modified gravity models.

Cometabolic Degradation of Dibenzofuran and Dibenzothiophene by a Naphthalene-Degrading Comamonas sp. JB.

PubMed

Ji, Xiangyu; Xu, Jing; Ning, Shuxiang; Li, Nan; Tan, Liang; Shi, Shengnan

2017-12-01

Comamonas sp. JB was used to investigate the cometabolic degradation of dibenzofuran (DBF) and dibenzothiophene (DBT) with naphthalene as the primary substrate. Dehydrogenase and ATPase activity of the growing system with the presence of DBF and DBT were decreased when compared to only naphthalene in the growing system, indicating that the presence of DBF and DBT inhibited the metabolic activity of strain JB. The pathways and enzymes involved in the cometabolic degradation were tested. Examination of metabolites elucidated that strain JB cometabolically degraded DBF to 1,2-dihydroxydibenzofuran, subsequently to 2-hydroxy-4-(3'-oxo-3'H-benzofuran-2'-yliden)but-2-enoic acid, and finally to catechol. Meanwhile, strain JB cometabolically degraded DBT to 1,2-dihydroxydibenzothiophene and subsequently to the ring cleavage product. A series of naphthalene-degrading enzymes including naphthalene dioxygenase, 1,2-dihydroxynaphthalene dioxygenase, salicylaldehyde dehydrogenase, salicylate hydroxylase, and catechol 2,3-oxygenase have been detected, confirming that naphthalene was the real inducer of expression the degradation enzymes and metabolic pathways were controlled by naphthalene-degrading enzymes.

Henry's Law and Noisy Knuckles.

ERIC Educational Resources Information Center

Kimbrough, Doris R.

1999-01-01

Discusses Henry's Law which describes the relationship between the pressure of gas and the concentration of that gas in a solution. Presents an application of Henry's Law to the cracking of knuckles. (CCM)

Remembering Dick Crane

NASA Astrophysics Data System (ADS)

Jossem, E. Leonard

2007-09-01

Physicist, polymath, educator, leader, Horace Richard Crane died on April 19, 2007, a few months short of his 100th birthday. Those of us who were fortunate enough to have had him as a friend mourn his loss, but for all of us he leaves a rich and varied legacy of published works that invite reading and rereading. Dick's work as a physicist was recognized in 1966 by his election to the National Academy of Sciences and in 1986 by the award of the President's National Medal of Science: "For the first measurement of the magnetic moment and spin of free electrons and positrons."

Henry (Hank) J. Moore (1928-1998)

NASA Astrophysics Data System (ADS)

Thompson, Thomas W.

Henry (Hank) J. Moore, a member of the AGU Planetary Sciences section, died of a heart attack on September 21, 1998. He was in Utah while on a family trip to visit his daughter. His 70th birthday occurred just 3 weeks before his death. Henry, who was born in Albuquerque, New Mexico, took great pride in having found and visited the small town of Albuquerque in the Extremadura region of Spain, noting the geologic similarities between that part of Spain and his birthplace in America.Henry, known for his contributions to the Apollo,Viking, Magellan, and Mars Pathfinder missions, attributed his career to a chance encounter with Gene Shoemaker in 1960. Henry was completing his Ph.D. work in geology at Stanford University and Gene obviously had spotted Henry's keen analytical mind. I suspect this pivotal meeting was far from a chance encounter.

Henry Gray's Anatomy.

PubMed

Pearce, J M S

2009-04-01

Little is generally known of Henry Gray, the author of Gray's Anatomy, and even less of his colleague Henry Vandyke Carter, who played a vital role in the dissections and illustrations leading to the production of the first volume in 1859. This essay attempts to sketch briefly the salient, know aspects of these two men and their divergent careers. It traces succinctly the subsequent fate of the unique anatomy book that has influenced and instructed almost every student of medicine. (c) 2009 Wiley-Liss, Inc.

Psychoactive bacteria Lactobacillus rhamnosus (JB-1) elicits rapid frequency facilitation in vagal afferents.

PubMed

Perez-Burgos, Azucena; Wang, Bingxian; Mao, Yu-Kang; Mistry, Bhavik; McVey Neufeld, Karen-Anne; Bienenstock, John; Kunze, Wolfgang

2013-01-15

Mounting evidence supports the influence of the gut microbiome on the local enteric nervous system and its effects on brain chemistry and relevant behavior. Vagal afferents are involved in some of these effects. We previously showed that ingestion of the probiotic bacterium Lactobacillus rhamnosus (JB-1) caused extensive neurochemical changes in the brain and behavior that were abrogated by prior vagotomy. Because information can be transmitted to the brain via primary afferents encoded as neuronal spike trains, our goal was to record those induced by JB-1 in vagal afferents in the mesenteric nerve bundle and thus determine the nature of the signals sent to the brain. Male Swiss Webster mice jejunal segments were cannulated ex vivo, and serosal and luminal compartments were perfused separately. Bacteria were added intraluminally. We found no evidence for translocation of labeled bacteria across the epithelium during the experiment. We recorded extracellular multi- and single-unit neuronal activity with glass suction pipettes. Within minutes of application, JB-1 increased the constitutive single- and multiunit firing rate of the mesenteric nerve bundle, but Lactobacillus salivarius (a negative control) or media alone were ineffective. JB-1 significantly augmented multiunit discharge responses to an intraluminal distension pressure of 31 hPa. Prior subdiaphragmatic vagotomy abolished all of the JB-1-evoked effects. This detailed exploration of the neuronal spike firing that encodes behavioral signaling to the brain may be useful to identify effective psychoactive bacteria and thereby offer an alternative new perspective in the field of psychiatry and comorbid conditions.

Finite-size scaling analysis in the two-photon Dicke model

NASA Astrophysics Data System (ADS)

Chen, Xiang-You; Zhang, Yu-Yu

2018-05-01

We perform a Schrieffer-Wolff transformation to the two-photon Dicke model by keeping the leading-order correction with a quartic term of the field, which is crucial for finite-size scaling analysis. Besides a spectral collapse as a consequence of two-photon interaction, the super-radiant phase transition is indicated by the vanishing of the excitation energy and the uniform atomic polarization. The scaling functions for the ground-state energy and the atomic pseudospin are derived analytically. The scaling exponents of the observables are the same as those in the standard Dicke model, indicating they are in the same universality class.

Dicke superradiance as nondestructive probe for the state of atoms in optical lattices

NASA Astrophysics Data System (ADS)

ten Brinke, Nicolai; Schützhold, Ralf

2016-04-01

We present a proposal for a probing scheme utilizing Dicke superradiance to obtain information about ultracold atoms in optical lattices. A probe photon is absorbed collectively by an ensemble of lattice atoms generating a Dicke state. The lattice dynamics (e.g., tunneling) affects the coherence properties of that Dicke state and thus alters the superradiant emission characteristics - which in turn provides insight into the lattice (dynamics). Comparing the Bose-Hubbard and the Fermi-Hubbard model, we find similar superradiance in the strongly interacting Mott insulator regime, but crucial differences in the weakly interacting (superfluid or metallic) phase. Furthermore, we study the possibility to detect whether a quantum phase transition between the two regimes can be considered adiabatic or a quantum quench.

{gamma} parameter and Solar System constraint in chameleon-Brans-Dicke theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saaidi, Kh.; Mohammadi, A.; Sheikhahmadi, H.

2011-05-15

The post Newtonian parameter is considered in the chameleon-Brans-Dicke model. In the first step, the general form of this parameter and also effective gravitational constant is obtained. An arbitrary function for f({Phi}), which indicates the coupling between matter and scalar field, is introduced to investigate validity of solar system constraint. It is shown that the chameleon-Brans-Dicke model can satisfy the solar system constraint and gives us an {omega} parameter of order 10{sup 4}, which is in comparable to the constraint which has been indicated in [19].

Revisiting the analogue of the Jebsen-Birkhoff theorem in Brans-Dicke gravity

NASA Astrophysics Data System (ADS)

Faraoni, Valerio; Hammad, Fayçal; Cardini, Adriana M.; Gobeil, Thomas

2018-04-01

We report the explicit form of the general static, spherically symmetric, and asymptotically flat solution of vacuum Brans-Dicke gravity in the Jordan frame, assuming that the Brans-Dicke scalar field has no singularities or zeros (except possibly for a central singularity). This general solution is conformal to the Fisher-Wyman geometry of Einstein theory and its nature depends on a scalar charge parameter. Apart from the Schwarzschild black hole, only wormhole throats and central naked singularities are possible.

Joseph Henry and the Telegraph

NASA Astrophysics Data System (ADS)

Hochfelder, David

1997-04-01

Morse's telegraph rested upon three scientific advances which occured between 1800 and 1830: the development of battery technology, the formulation of laws governing the behavior of electrical components in circuits, and the discovery of electromagnetic phenomena. Joseph Henry was crucial to the development of the early telegraph. His work on electromagnetism made it possible for the electric current to manifest itself as useful mechanical work. Henry developed electromagnets of sufficient lifting power, but which drew relatively small currents; these magnets were the heart of Morse's telegraph receiver. Morse also used electromagnets as relays, which allowed him to transmit signals over great distances. Morse often acknowledged his debt to Henry, and the two enjoyed a cordial working relationship until the mid-1840s. But during the bitter and protracted litigation over Morse's patent, Henry testified (unwillingly, he claimed) against the inventor. This began a lifelong quarrel between the two men, the specifics of which were tedious and petty. In general terms, however, their conflict arose over different notions regarding scientific discovery and technological innovation.

Compilation of Henry's law constants, version 3.99

NASA Astrophysics Data System (ADS)

Sander, R.

2014-11-01

Many atmospheric chemicals occur in the gas phase as well as in liquid cloud droplets and aerosol particles. Therefore, it is necessary to understand the distribution between the phases. According to Henry's law, the equilibrium ratio between the abundances in the gas phase and in the aqueous phase is constant for a dilute solution. Henry's law constants of trace gases of potential importance in environmental chemistry have been collected and converted into a uniform format. The compilation contains 14775 values of Henry's law constants for 3214 species, collected from 639 references. It is also available on the internet at henrys-law.org">http://www.henrys-law.org.

Henri Poincaré: Death centenary (1854-1912)

NASA Astrophysics Data System (ADS)

Heinzmann, Gerhard; Villani, Cédric

2014-08-01

The year 2012 marked the centenary of the death of Henri Poincaré (Nancy, 1854-Paris, 1912), and through the agency of the Henri-Poincaré Institute in Paris, the Henri-Poincaré Archives in Nancy and The London Mathematical Society, brought with it several exhibitions and meetings commemorating one of the greatest minds in contemporary times. Often referred to as the last polymath, Poincaré embraced multiple branches of mathematics, theoretical physics and celestial mechanics, and made significant contributions to philosophy of science (Heinzmann & Stump, Henri Poincaré, 2013). He wrote 25 textbooks and monographs, 500-plus articles, and was deeply involved in the organization and administration of science at both the national and international levels.1

TEACHING "MOBY DICK," A METHOD AND AN APPROACH.

ERIC Educational Resources Information Center

JOSEPHS, LOIS

"MOBY DICK" IS SINGULARLY APPROPRIATE FOR HIGH SCHOOL STUDENTS IN ITS PHILOSOPHICAL, PSYCHOLOGICAL, AND SOCIAL EMPHASIS. HOWEVER, TO GUIDE THE STUDENTS INTO THE THEMATIC INTRICACIES OF THE WORK, THE TEACHER MUST USE A CAREFULLY PLANNED, INDUCTIVE APPROACH THAT DEMANDS CLOSE TEXTUAL STUDY IN CLASS. ALTHOUGH EACH TEACHER SHOULD CONCENTRATE…

Axially Symmetric Brans-Dicke-Maxwell Solutions

NASA Astrophysics Data System (ADS)

Chatterjee, S.

1981-05-01

Following a method of John and Goswami new solutions of coupled Brans-Dicke-Maxwell theory are generated from Zipoy's solutions in oblate and prolate spheroidal coordinates for source-free gravitational field. All these solutions become Euclidean at infinity. The asymptotic behavior and the singularity of the solutions are discussed and a comparative study made with the corresponding Einstein-Maxwell solutions. The possibility of a very large red shift from the boundary of the spheroids is also discussed.

Integrability and superintegrability of the generalized n-level many-mode Jaynes-Cummings and Dicke models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Skrypnyk, T.

2009-10-15

We analyze symmetries of the integrable generalizations of Jaynes-Cummings and Dicke models associated with simple Lie algebras g and their reductive subalgebras g{sub K}[T. Skrypnyk, 'Generalized n-level Jaynes-Cummings and Dicke models, classical rational r-matrices and nested Bethe ansatz', J. Phys. A: Math. Theor. 41, 475202 (2008)]. We show that their symmetry algebras contain commutative subalgebras isomorphic to the Cartan subalgebras of g, which can be added to the commutative algebras of quantum integrals generated with the help of the quantum Lax operators. We diagonalize additional commuting integrals and constructed with their help the most general integrable quantum Hamiltonian of themore » generalized n-level many-mode Jaynes-Cummings and Dicke-type models using nested algebraic Bethe ansatz.« less

Henry VIII, McLeod syndrome and Jacquetta's curse.

PubMed

Stride, P; Lopes Floro, K

2013-01-01

The mental decline of King Henry VIII from being a jovial, charismatic and athletic young man into an increasingly paranoid, brutal tyrant in later life, ever more concerned at his lack of one or more male heirs, has attracted many medical diagnostic theories. Previous hypotheses have included diabetes, syphilis and hypothyroidism, among others. However, these inadequately explain Henry's failure to produce a male heir, despite multiple pairings. The latest postulated diagnoses for Henry are the coexistence of both Kell blood group antigenicity (possibly inherited from Jacquetta Woodville, Henry's maternal great grandmother) causing related impaired fertility, and McLeod syndrome, causing psychotic changes. As the mutated McLeod protein of the syndrome significantly reduces the expression, effectively inactivating the Kell antigen, we critically review this theory, examining in detail the pathophysiology of these conditions and assessing the genealogy of Henry VIII and its effect in subsequent generations.

John Henry--The Steel Driving Man

ERIC Educational Resources Information Center

Murphy, David E.; Gulley, Laura L.

2005-01-01

The story of John Henry provided the setting for sixth-grade class to participate in a John Henry Day of mathematics experiments. The students collected data from experiments where students competed against machines and technology. The student analyzed the data by comparing two box plots, a box plot of human data, and a box plot of machine or…

Generalized Brans-Dicke theories

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Felice, Antonio; Tsujikawa, Shinji, E-mail: defelice@rs.kagu.tus.ac.jp, E-mail: shinji@rs.kagu.tus.ac.jp

2010-07-01

In Brans-Dicke theory a non-linear self interaction of a scalar field φ allows a possibility of realizing the late-time cosmic acceleration, while recovering the General Relativistic behavior at early cosmological epochs. We extend this to more general modified gravitational theories in which a de Sitter solution for dark energy exists without using a field potential. We derive a condition for the stability of the de Sitter point and study the background cosmological dynamics of such theories. We also restrict the allowed region of model parameters from the demand for the avoidance of ghosts and instabilities. A peculiar evolution of themore » field propagation speed allows us to distinguish those theories from the ΛCDM model.« less

The Truth of the Thing: Nonfiction in "Moby Dick"

ERIC Educational Resources Information Center

Hilbert, Betsy

1986-01-01

Looks at Melville's narrative construction of "onion-like...layers of truth" that combine romance and textbook, presents critics' discussion and scholars' treatment of the cetological information present in the text, offers an explanation for the lack of recognition due to the nonfictional parts of "Moby Dick." (JK)

Isolation of Burkholderia cepacia JB12 from lead- and cadmium-contaminated soil and its potential in promoting phytoremediation with tall fescue and red clover.

PubMed

Jin, Zhong Min; Sha, Wei; Zhang, Yan Fu; Zhao, Jing; Ji, Hongyang

2013-07-01

Phytoremediation combined with suitable microorganisms and biodegradable chelating agents can be a means of reclaiming lands contaminated by toxic heavy metals. We investigated the ability of a lead- and cadmium-resistant bacterial strain (JB12) and the biodegradable chelator ethylenediamine-N,N'-disuccinic acid (EDDS) to improve absorption of these metals from soil by tall fescue and red clover. Strain JB12 was isolated from contaminated soil samples, analysed for lead and cadmium resistance, and identified as Burkholderia cepacia. Tall fescue and red clover were grown in pots to which we added JB12, (S,S)-EDDS, combined JB12 and EDDS, or water only. Compared with untreated plants, the biomass of plants treated with JB12 was significantly increased. Concentrations of lead and cadmium in JB12-treated plants increased significantly, with few exceptions. Plants treated with EDDS responded variably, but in those treated with combined EDDS and JB12, heavy metal concentrations increased significantly in tall fescue and in the aboveground parts of red clover. We conclude that JB12 is resistant to lead and cadmium. Its application to the soil improved the net uptake of these heavy metals by experimental plants. The potential for viable phytoremediation of lead- and cadmium-polluted soils with tall fescue and red clover combined with JB12 was further enhanced by the addition of EDDS.

Joseph Henry's Conception of Scientific Knowledge

NASA Astrophysics Data System (ADS)

Theerman, Paul

1997-04-01

Joseph Henry, America's premier physicist and physics teacher in the mid-nineteenth century, had decided views of scientific knowledge. These were expressed in two ways. First of all, scientific knowledge led to moral betterment. Thus the study of science was a morally good thing. This was not only because it led to the contemplation of God's creation, which was a standard reason justifying the study of science dating from the Scientific Revolution and even earlier. More importantly, the study of science itself was a moral discipline, imparting to scientists the habits and virtues of truthfulness, respect for others, care and diligence, and the discernment of meaningful patterns from experience. The moral ideals of science were expressed most strongly in Henry's upholding the international "Republic of Science"; conversely, cheapening science was a sign of moral failure. Second, for Henry and his generation, science provided a path to sure truth, separate from falsehood of both the politics and the quackery that characterized mid-century public life. Henry promoted this in his championing of the Smithsonian Institution a scientific establishment, against the ideas of others who wanted to make it a literary establishment or a training school for teachers. For Henry, the Smithsonian's scientific reputation would be established by relying on careful peer review in its publications, and supporting established scientists to write authoritative popular works. The purpose of both these activities was to raise the profile of science in the United States and further establish science and the scientific method as a guide to public life.

Comparison of the insulin reaction of peripheral blood T cells between healthy Holstein dairy cows and JB during the periparturient period.

PubMed

Ohtsuka, Hiromichi; Kitagawa, Madoka; Kohiruimaki, Masayuki; Tanami, Erika; Masui, Machiko; Hayashi, Tomohito; Ando, Takaaki; Watanabe, Daisaku; Koiwa, Masateru; Sato, Shigeru; Kawamura, Seiichi

2006-11-01

To compare the changes in the insulin reaction of Holstein dairy cows and Japanese Black cows (JB) during the periparturient period, the insulin resistance test in vivo and lymphocytes proliferation with insulin in vitro were performed. Ten healthy Holstein dairy cows (Holstein group) and 10 healthy JB cows (JB group) used in this study were observed on days 60, 40, and 20 before calving and days 7 and 20 after calving. In insulin resistance reaction in vivo and in vitro, a low insulin-stimulated glucose disposal rate and lymphocyte proliferation with insulin were observed in the Holstein group compared with the JB group during the experimental period. An analysis of the lymphocytes cultured with insulin showed that the percentage of CD4+CD45R- T cells in the Holstein group was significantly lower than that of the JB group before day 20. These findings indicate that T cells reaction to insulin in healthy periparturient Holstein cows is lower than that in Japanese Black.

Gravitational collapse in Husain space-time for Brans-Dicke gravity theory with power-law potential

NASA Astrophysics Data System (ADS)

Rudra, Prabir; Biswas, Ritabrata; Debnath, Ujjal

2014-12-01

The motive of this work is to study gravitational collapse in Husain space-time in Brans-Dicke gravity theory. Among many scalar-tensor theories of gravity, Brans-Dicke is the simplest and the impact of it can be regulated by two parameters associated with it, namely, the Brans-Dicke parameter, ω, and the potential-scalar field dependency parameter n respectively. V. Husain's work on exact solution for null fluid collapse in 1996 has influenced many authors to follow his way to find the end-state of the homogeneous/inhomogeneous dust cloud. Vaidya's metric is used all over to follow the nature of future outgoing radial null geodesics. Detecting whether the central singularity is naked or wrapped by an event horizon, by the existence of future directed radial null geodesic emitted in past from the singularity is the basic objective. To point out the existence of positive trajectory tangent solution, both particular parametric cases (through tabular forms) and wide range contouring process have been applied. Precisely, perfect fluid's EoS satisfies a wide range of phenomena: from dust to exotic fluid like dark energy. We have used the EoS parameter k to determine the end state of collapse in different cosmological era. Our main target is to check low ω (more deviations from Einstein gravity-more Brans Dicke effect) and negative k zones. This particularly throws light on the nature of the end-state of collapse in accelerated expansion in Brans Dicke gravity. It is seen that for positive values of EoS parameter k, the collapse results in a black hole, whereas for negative values of k, naked singularity is the only outcome. It is also to be noted that "low ω" leads to the possibility of getting more naked singularities even for a non-accelerating universe.

Gravitational Collapse in Husain space-time for Brans-Dicke Gravity Theory with Power-law Potential.

NASA Astrophysics Data System (ADS)

Rudra, Prabir

2016-07-01

The motive of this work is to study gravitational collapse in Husain space-time in Brans-Dicke gravity theory. Among many scalar-tensor theories of gravity, Brans-Dicke is the simplest and the impact of it can be regulated by two parameters associated with it, namely, the Brans-Dicke parameter, ω, and the potential-scalar field dependency parameter 'n' respectively. V. Husain's work on exact solution for null fluid collapse in 1996 has influenced many authors to follow his way to find the end-state of the homogeneous/inhomogeneous dust cloud. Vaidya's metric is used all over to follow the nature of future outgoing radial null geodesics. Detecting whether the central singularity is naked or wrapped by an event horizon, by the existence of future directed radial null geodesic emitted in past from the singularity is the basic objective. To point out the existence of positive trajectory tangent solution, both particular parametric cases(through tabular forms) and wide range contouring process have been applied. Precisely, perfect fluid's equation of state satisfies a wide range of phenomena : from dust to exotic fluid like dark energy. We have used the equation of state parameter 'k' to determine the end state of collapse in different cosmological era. Our main target is to check low ω (more deviations from Einstein gravity-more Brans Dicke effect) and negative 'k' zones. This particularly throws light on the nature of the end-state of collapse in accelerated expansion in Brans Dicke gravity. It is seen that for positive values of EoS parameter 'k', the collapse results in a black hole, whereas for negative values of 'k', naked singularity is the only outcome. It is also to be noted that "low ω" leads to the possibility of getting more naked singularities even for a non-accelerating universe.

Brans-Dicke Theory with Λ>0: Black Holes and Large Scale Structures.

PubMed

Bhattacharya, Sourav; Dialektopoulos, Konstantinos F; Romano, Antonio Enea; Tomaras, Theodore N

2015-10-30

A step-by-step approach is followed to study cosmic structures in the context of Brans-Dicke theory with positive cosmological constant Λ and parameter ω. First, it is shown that regular stationary black-hole solutions not only have constant Brans-Dicke field ϕ, but can exist only for ω=∞, which forces the theory to coincide with the general relativity. Generalizations of the theory in order to evade this black-hole no-hair theorem are presented. It is also shown that in the absence of a stationary cosmological event horizon in the asymptotic region, a stationary black-hole horizon can support a nontrivial Brans-Dicke hair. Even more importantly, it is shown next that the presence of a stationary cosmological event horizon rules out any regular stationary solution, appropriate for the description of a star. Thus, to describe a star one has to assume that there is no such stationary horizon in the faraway asymptotic region. Under this implicit assumption generic spherical cosmic structures are studied perturbatively and it is shown that only for ω>0 or ω≲-5 their predicted maximum sizes are consistent with observations. We also point out how, many of the conclusions of this work differ qualitatively from the Λ=0 spacetimes.

Bianchi type-I domain walls with negative constant deceleration parameter in Brans-Dicke theory

NASA Astrophysics Data System (ADS)

Katore, S. D.

2011-04-01

Bianchi type-I space-time is considered in the presence of a domain walls source in the scalar-tensor theory of gravitation proposed by Brans and Dicke (C.H. Brans and R.H. Dicke, Phys. Rev. 24, 925 (1961)). With the help of the special law of variation for Hubble's parameter proposed by Bermann (M.S. Berman, Nuovo Cimento B 74, 182 (1983)) a cosmological model with negative constant deceleration parameter is obtained in the presence of domain walls. Some physical properties of the model are also discussed.

The Don Henry Story. Teaching with Documents.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC.

Don Henry was a student at the University of Kansas (Lawrence, Kansas) who experienced a profound political change during his years on campus. Henry became a leader in radical campus organizations, volunteered to fight in the Spanish Civil War with the Lincoln Brigade, and died on the battlefield in Aragon (Spain) in September 1937. An article in…

Author! Author! The Gallant Children's Author: Dick King-Smith

ERIC Educational Resources Information Center

Brodie, Carolyn S.

2005-01-01

This column presents a brief biography of Dick King-Smith. Born on March 27, 1922 and raised in Gloucestershire, England, he grew up with animals of all kinds. King-Smith was a farmer for twenty years and then became a school teacher. He was also a soldier during wartime, a traveling salesman, shoe factory worker, and television presenter. He…

Loss of retrovirus production in JB/RH melanoma cells transfected with H-2Kb and TAP-1 genes.

PubMed

Li, M; Xu, F; Muller, J; Huang, X; Hearing, V J; Gorelik, E

1999-01-20

JB/RH1 melanoma cells, as well as other melanomas of C57BL/6 mice (B16 and JB/MS), express a common melanoma-associated antigen (MAA) encoded by an ecotropic melanoma-associated retrovirus (MelARV). JB/RH1 cells do not express the H-2Kb molecules due to down-regulation of the H-2Kb and TAP-1 genes. When JB/RH1 cells were transfected with the H-2Kb and cotransfected with the TAP-1 gene, it resulted in the appearance of H-2Kb molecules and an increase in their immunogenicity, albeit they lost expression of retrovirus-encoded MAA recognized by MM2-9B6 mAb. Loss of MAA was found to result from a complete and stable elimination of ecotropic MelARV production in the H-2Kb/TAP-1-transfected JB/RH1 cells. Northern blot analysis showed no differences in ecotropic retroviral messages in MelARV-producing and -nonproducing melanoma cells, suggesting that loss of MelARV production was not due to down-regulation of MelARV transcription. Southern blot analysis revealed several rearrangements in the proviral DNA of H-2Kb-positive JB/RH1 melanoma cells. Sequence analysis of the ecotropic proviral DNA from these cells showed numerous nucleotide substitutions, some of which resulted in the appearance of a novel intraviral PstI restriction site and the loss of a HindIII restriction site in the pol region. PCR amplification of the proviral DNAs indicates that an ecotropic provirus found in the H-2Kb-positive cells is novel and does not preexist in the parental H-2Kb-negative melanoma cells. Conversely, the ecotropic provirus of the parental JB/RH1 cells was not amplifable from the H-2Kb-positive cells. Our data indicate that stable loss of retroviral production in the H-2Kb/TAP-1-transfected melanoma cells is probably due to the induction of recombination between a productive ecotropic MelARV and a defective nonecotropic provirus leading to the generation of a defective ecotropic provirus and the loss of MelARV production and expression of the retrovirus-encoded MAA. Copyright 1999

Solar oblateness from Archimedes to Dicke

NASA Astrophysics Data System (ADS)

Sigismondi, C.; Oliva, P.

2005-10-01

The non-spherical shape of the Sun has been invoked to explain the anomalous precession of Mercury. A brief history of some methods for measuring the solar diameter is presented. Archimedes was the first to give upper and lower values for the solar diameter in the third century before Christ. Then there followed the method of total eclipses, used after Halley's observative campaign of 1715 eclipse. We will also discuss the variant of partial eclipses, useful to measure different chords of the solar disk and the method of Dicke, which correlates oblateness with luminous excess in the equatorial zone.

Brans-Dicke inflation in light of the Planck 2015 data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tahmasebzadeh, B.; Rezazadeh, K.; Karami, K., E-mail: b.tahmasebzadeh@iasbs.ac.ir, E-mail: rezazadeh86@gmail.com, E-mail: kkarami@uok.ac.ir

We study inflation in the Brans-Dicke gravity as a special model of the scalar-tensor gravity. We obtain the inflationary observables containing the scalar spectral index, the tensor-to-scalar ratio, the running of the scalar spectral index and the equilateral non-Gaussianity parameter in terms of the general form of the potential in the Jordan frame. Then, we compare the results for various inflationary potentials in light of the Planck 2015 data. Our study shows that in the Brans-Dicke gravity, the power-law, inverse power-law and exponential potentials are ruled out by the Planck 2015 data. But, the hilltop, Higgs, Coleman-Weinberg and natural potentialsmore » can be compatible with Planck 2015 TT,TE,EE+lowP data at 95% CL. Moreover, the D-brane, SB SUSY and displaced quadratic potentials can be in well agreement with the observational data since their results can lie inside the 68% CL region of Planck 2015 TT,TE,EE+lowP data.« less

Embedding, serial sectioning and staining of zebrafish embryos using JB-4 resin.

PubMed

Sullivan-Brown, Jessica; Bisher, Margaret E; Burdine, Rebecca D

2011-01-01

Histological techniques are critical for observing tissue and cellular morphology. In this paper, we outline our protocol for embedding, serial sectioning, staining and visualizing zebrafish embryos embedded in JB-4 plastic resin-a glycol methacrylate-based medium that results in excellent preservation of tissue morphology. In addition, we describe our procedures for staining plastic sections with toluidine blue or hematoxylin and eosin, and show how to couple these stains with whole-mount RNA in situ hybridization. We also describe how to maintain and visualize immunofluorescence and EGFP signals in JB-4 resin. The protocol we outline-from embryo preparation, embedding, sectioning and staining to visualization-can be accomplished in 3 d. Overall, we reinforce that plastic embedding can provide higher resolution of cellular details and is a valuable tool for cellular and morphological studies in zebrafish.

A novel chimeric prophage vB_LdeS-phiJB from commercial Lactobacillus delbrueckii subsp. bulgaricus.

PubMed

Guo, Tingting; Zhang, Chenchen; Xin, Yongping; Xin, Min; Kong, Jian

2016-05-01

Prophage vB_LdeS-phiJB (phiJB) was induced by mitomycin C and UV radiation from the Lactobacillus delbrueckii subsp. bulgaricus SDMCC050201 isolated from a Chinese yoghurt sample. It has an isometric head and a non-contractile tail with 36,969 bp linear double-stranded DNA genome, which is classified into the group a of Lb. delbrueckii phages. The genome of phiJB is highly modular with functionally related genes clustered together. Unexpectedly, there is no similarity of its DNA replication module to any phages that have been reported, while it consists of open-reading frames homologous to the proteins of Lactobacillus strains. Comparative genomic analysis indicated that its late gene clusters, integration/lysogeny modules and DNA replication module derived from different evolutionary ancestors and integrated into a chimera. Our results revealed a novel chimeric phage of commercial Lb. delbrueckii and will broaden the knowledge of phage diversity in the dairy industry.

Annual Progress Report, January 1, 1969 through December 31, 1969.

DTIC Science & Technology

1970-02-01

or extended. E. The Role of CAI in Curriculum Revision I The Intermediate Science Curriculum Study (ISCS)* (Dr. Ernest Burkman, i Director and Dr David...Educational Research, FSU. Henry T. Lippert , Ed.D., 1967, Education, University of Illinois, Research Associate in the CAI Center and Assistant...Walter Dick, and Henry T Lippert , Tech Report 3, Florida State University, Tallahassee, 1968 "A Systematic Investigation of Three Facets of Programmed

Hamiltonian formulation of Palatini f(R) theories a la Brans-Dicke theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olmo, Gonzalo J.; Sanchis-Alepuz, Helios; Institut fuer Physik, Karl-Franzens-Universitaet Graz

2011-05-15

We study the Hamiltonian formulation of f(R) theories of gravity both in metric and in Palatini formalism using their classical equivalence with Brans-Dicke theories with a nontrivial potential. The Palatini case, which corresponds to the {omega}=-3/2 Brans-Dicke theory, requires special attention because of new constraints associated with the scalar field, which is nondynamical. We derive, compare, and discuss the constraints and evolution equations for the {omega}=-3/2 and {omega}{ne}-3/2 cases. Based on the properties of the constraint and evolution equations, we find that, contrary to certain claims in the literature, the Cauchy problem for the {omega}=-3/2 case is well formulated andmore » there is no reason to believe that it is not well posed in general.« less

Henry Ford Health Systems

Cancer.gov

Henry Ford Health Systems evolved from a hospital into a system delivering care to 2.5 million patients and includes the Cancer Epidemiology, Prevention and Control Program, which focuses on epidemiologic and public health aspects of cancer.

Possible Pasts: Historiography and Legitimation in "Henry VIII."

ERIC Educational Resources Information Center

Kamps, Ivo

1996-01-01

Aims to rehabilitate the reputation of Shakespeare's "Henry VIII" and emphasizes its potential usefulness in the classroom by reconsidering it in the context of Renaissance history writing. Shows how "Henry VIII" can be taught as a commentary on or seen as a continuation of incipient themes in "The Tempest" and…

Human dendritic cell DC-SIGN and TLR-2 mediate complementary immune regulatory activities in response to Lactobacillus rhamnosus JB-1.

PubMed

Konieczna, Patrycja; Schiavi, Elisa; Ziegler, Mario; Groeger, David; Healy, Selena; Grant, Ray; O'Mahony, Liam

2015-01-01

The microbiota is required for optimal host development and ongoing immune homeostasis. Lactobacilli are common inhabitants of the mammalian large intestine and immunoregulatory effects have been described for certain, but not all, strains. The mechanisms underpinning these protective effects are beginning to be elucidated. One such protective organism is Lactobacillus rhamnosus JB-1 (Lb. rhamnosus JB-1). Lb. murinus has no such anti-inflammatory protective effects and was used as a comparator organism. Human monocyte-derived dendritic cells (MDDCs) were co-incubated with bacteria and analysed over time for bacterial adhesion and intracellular processing, costimulatory molecule expression, cytokine secretion and induction of lymphocyte polarization. Neutralising antibodies were utilized to identify the responsible MDDC receptors. Lb. rhamnosus JB-1 adhered to MDDCs, but internalization and intracellular processing was significantly delayed, compared to Lb. murinus which was rapidly internalized and processed. Lb. murinus induced CD80 and CD86 expression, accompanied by high levels of cytokine secretion, while Lb. rhamnosus JB-1 was a poor inducer of costimulatory molecule expression and cytokine secretion. Lb. rhamnosus JB-1 primed MDDCs induced Foxp3 expression in autologous lymphocytes, while Lb. murinus primed MDDCs induced Foxp3, T-bet and Ror-γt expression. DC-SIGN was required for Lb. rhamnosus JB-1 adhesion and influenced IL-12 secretion, while TLR-2 influenced IL-10 and IL-12 secretion. Here we demonstrate that the delayed kinetics of bacterial processing by MDDCs correlates with MDDC activation and stimulation of lymphocytes. Thus, inhibition or delay of intracellular processing may be a novel strategy by which certain commensals may avoid the induction of proinflammatory responses.

Human Dendritic Cell DC-SIGN and TLR-2 Mediate Complementary Immune Regulatory Activities in Response to Lactobacillus rhamnosus JB-1

PubMed Central

Konieczna, Patrycja; Schiavi, Elisa; Ziegler, Mario; Groeger, David; Healy, Selena; Grant, Ray; O’Mahony, Liam

2015-01-01

The microbiota is required for optimal host development and ongoing immune homeostasis. Lactobacilli are common inhabitants of the mammalian large intestine and immunoregulatory effects have been described for certain, but not all, strains. The mechanisms underpinning these protective effects are beginning to be elucidated. One such protective organism is Lactobacillus rhamnosus JB-1 (Lb. rhamnosus JB-1). Lb. murinus has no such anti-inflammatory protective effects and was used as a comparator organism. Human monocyte-derived dendritic cells (MDDCs) were co-incubated with bacteria and analysed over time for bacterial adhesion and intracellular processing, costimulatory molecule expression, cytokine secretion and induction of lymphocyte polarization. Neutralising antibodies were utilized to identify the responsible MDDC receptors. Lb. rhamnosus JB-1 adhered to MDDCs, but internalization and intracellular processing was significantly delayed, compared to Lb. murinus which was rapidly internalized and processed. Lb. murinus induced CD80 and CD86 expression, accompanied by high levels of cytokine secretion, while Lb. rhamnosus JB-1 was a poor inducer of costimulatory molecule expression and cytokine secretion. Lb. rhamnosus JB-1 primed MDDCs induced Foxp3 expression in autologous lymphocytes, while Lb. murinus primed MDDCs induced Foxp3, T-bet and Ror-γt expression. DC-SIGN was required for Lb. rhamnosus JB-1 adhesion and influenced IL-12 secretion, while TLR-2 influenced IL-10 and IL-12 secretion. Here we demonstrate that the delayed kinetics of bacterial processing by MDDCs correlates with MDDC activation and stimulation of lymphocytes. Thus, inhibition or delay of intracellular processing may be a novel strategy by which certain commensals may avoid the induction of proinflammatory responses. PMID:25816321

The Henry's constant of monochloramine.

PubMed

Garcia, Miguel A; Anderson, Michael A

2018-02-01

Monochloramine is a secondary disinfectant used in drinking water and is also formed in chlorinated wastewater. While known to hydrolyze over time and react with dissolved organic matter, its partitioning between the aqueous and gas phase has not been extensively studied. Preliminary experiments demonstrated that monochloramine concentrations in solutions open to the atmosphere or actively aerated decreased more rapidly than in sealed solutions, indicating significant losses to the atmosphere. For example, a monochloramine solution open to the atmosphere yielded a loss rate constant of 0.08 d -1 , a value twice that for sealed samples without headspace (0.04 d -1 ) where loss occurs exclusively as a result of hydrolysis. A solution aerated at 10 mL s -1 had a loss rate constant nearly 10× greater than that for hydrolysis alone (0.35 d -1 ). To better understand partitioning of monochloramine to the gas phase and potential for volatilization, the dimensionless Henry's law constants of monochloramine (K H ) were determined using an equilibrium headspace technique at five different temperatures (11, 16, 21, 27, and 32 °C). The resulting values ranged from 8 × 10 -3 to 4 × 10 -2 , indicating a semi-volatile compound, and were found to be consistent with quantitative structure activity relationship predictions. At 20 °C, monochloramine exhibits a dimensionless Henry's constant of about 1.7 × 10 -2 which is 35 times greater than ammonia but comparable to the Henry's constant of inorganic semi-volatile compounds such sulfur dioxide. The Henry's constant values for monochloramine suggests that volatilization could be a relevant loss process in open systems such as rivers receiving chlorinated wastewater effluent, swimming pools and cooling towers. Copyright © 2017 Elsevier Ltd. All rights reserved.

Reactive flow modeling of initial density effect on divergence JB-9014 detonation driving

NASA Astrophysics Data System (ADS)

Yu, Xin; Huang, Kuibang; Zheng, Miao

2016-06-01

A serious of experiments were designed and the results were represented in this paper, in which 2mm thickness cooper shells were impacted by explosives named JB-9014 with different densities, and the surface velocities of the OFHC shells were measured. The comparison of experimental data shows the free surface velocity of the OFHC shell increase with the IHE density. Numerical modeling, which occupied phenomenological reactive flow rate model using the two-dimensional Lagrange hydrodynamic code, were carried out to simulate the above experiments, and empirical adjustments on detonation velocity and pressure and Pier Tang's adjustments on EOS of detonation products were both introduced in our numerical simulation work. The computational results agree well with that of experiments, and the numerical results with original parameters of products and the adjusted ones of JB-9014 could describe the density effect distinctly.

Biosorption of cationic basic dye and cadmium by the novel biosorbent Bacillus catenulatus JB-022 strain.

PubMed

Kim, Su Young; Jin, Mi Ra; Chung, Chang Ho; Yun, Yeoung-Sang; Jahng, Kwang Yeop; Yu, Kang-Yeol

2015-04-01

Biosorption of heavy metals and dyes is a promising technology that involves the removal of toxic metals from industrial wastes. The present study aims to screen the bacterial strains isolated from soils and polluted pond for their potential biosorption of both cationic dye and cadmium. Bacillus catenulatus JB-022 strain removed 58% and 66% of cationic basic blue 3 (BB3) and cadmium (Cd(II)) at the respective concentrations of 2000 mg/L and 150 mg/L. The biosorption equilibrium data were well fitted by the Langmuir adsorption isotherm, and the kinetic studies indicated that the biosorption followed the pseudo-second-order model. The biosorption kinetics showed that the equilibrium was reached within 10 min and 5 min for BB3 and Cd(II), respectively. According to the Langmuir model, the maximum uptakes of BB3 and Cd(II) by the JB-022 biomass were estimated to be 139.74 and 64.28 mg/g, respectively. To confirm the surface morphology and functional groups, field emission scanning electron microscope, energy-dispersive X-ray spectrometer, X-ray diffraction, and Fourier transform infrared spectroscopy analyses were carried out, and the results revealed that the biomass of JB-022 has carboxyl and phosphonate groups as potential surface functional groups capable of binding to cationic pollutants. In conclusion, B. catenulatus JB-022 is proposed as an excellent biosorbent with potentially important applications in removal of cationic pollutants from wastewaters. Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Compilation of Henry's law constants (version 4.0) for water as solvent

NASA Astrophysics Data System (ADS)

Sander, R.

2015-04-01

Many atmospheric chemicals occur in the gas phase as well as in liquid cloud droplets and aerosol particles. Therefore, it is necessary to understand the distribution between the phases. According to Henry's law, the equilibrium ratio between the abundances in the gas phase and in the aqueous phase is constant for a dilute solution. Henry's law constants of trace gases of potential importance in environmental chemistry have been collected and converted into a uniform format. The compilation contains 17 350 values of Henry's law constants for 4632 species, collected from 689 references. It is also available at henrys-law.org"target="_blank">http://www.henrys-law.org.

Generalized Dicke Nonequilibrium Dynamics in Trapped Ions

NASA Astrophysics Data System (ADS)

Genway, Sam; Li, Weibin; Ates, Cenap; Lanyon, Benjamin P.; Lesanovsky, Igor

2014-01-01

We explore trapped ions as a setting to investigate nonequilibrium phases in a generalized Dicke model of dissipative spins coupled to phonon modes. We find a rich dynamical phase diagram including superradiantlike regimes, dynamical phase coexistence, and phonon-lasing behavior. A particular advantage of trapped ions is that these phases and transitions among them can be probed in situ through fluorescence. We demonstrate that the main physical insights are captured by a minimal model and consider an experimental realization with Ca+ ions trapped in a linear Paul trap with a dressing scheme to create effective two-level systems with a tunable dissipation rate.

77 FR 70159 - Knueppel, Henry W.; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-7020-000] Knueppel, Henry W.; Notice of Filing Take notice that on November 15, 2012, Henry W. Knueppel submitted for filing, an application for authority to hold interlocking positions, pursuant to section 305(b) of the...

Biodegradation of Benzene, Toluene, Ethylbenzene, and o-, m-, and p-Xylenes by the Newly Isolated Bacterium Comamonas sp. JB.

PubMed

Jiang, Bei; Zhou, Zunchun; Dong, Ying; Tao, Wei; Wang, Bai; Jiang, Jingwei; Guan, Xiaoyan

2015-07-01

A bacterium designated strain JB, able to degrade six benzene, toluene, ethylbenzene, and o-, m-, and p-xylene (BTEX) compounds, was isolated from petroleum-contaminated soil. Taxonomic analyses showed that the isolate belonged to Comamonas, and until now, the genus Comamonas has not included any known BTEX degraders. The BTEX biodegradation rate was slightly low on the mineral salt medium (MSM), but adding a small amount of yeast extract greatly enhanced the biodegradation. The relationship between specific degradation rate and individual BTEX was described well by Michaelis-Menten kinetics. The treatment of petrochemical wastewater containing BTEX mixture and phenol was shown to be highly efficient by BTEX-grown JB. In addition, toxicity assessment indicated the treatment of the petrochemical wastewater by BTEX-grown JB led to less toxicity than untreated wastewater.

Revisiting Yasinsky and Henry`s benchmark using modern nodal codes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feltus, M.A.; Becker, M.W.

1995-12-31

The numerical experiments analyzed by Yasinsky and Henry are quite trivial by comparison with today`s standards because they used the finite difference code WIGLE for their benchmark. Also, this problem is a simple slab (one-dimensional) case with no feedback mechanisms. This research attempts to obtain STAR (Ref. 2) and NEM (Ref. 3) code results in order to produce a more modern kinetics benchmark with results comparable WIGLE.

Lagrangian circulation study near Cape Henry, Virginia. [Chesapeake Bay

NASA Technical Reports Server (NTRS)

Johnson, R. E.

1981-01-01

A study of the circulation near Cape Henry, Virginia, was made using surface and seabed drifters and radar tracked surface buoys coupled to subsurface drag plates. Drifter releases were conducted on a line normal to the beach just south of Cape Henry. Surface drifter recoveries were few; wind effects were strongly noted. Seabed drifter recoveries all exhibited onshore motion into Chesapeake Bay. Strong winds also affected seabed recoveries, tending to move them farther before recovery. Buoy trajectories in the vicinity of Cape Henry appeared to be of an irrotational nature, showing a clockwise rotary tide motion. Nearest the cape, the buoy motion elongated to almost parallel depth contours around the cape. Buoy motion under the action of strong winds showed that currents to at least the depth of the drag plates substantially are altered from those of low wind conditions near the Bay mouth. Only partial evidence could be found to support the presence of a clockwise nontidal eddy at Virginia Beach, south of Cape Henry.

Straight spinning cosmic strings in Brans-Dicke gravity

NASA Astrophysics Data System (ADS)

Dos Santos, S. Mittmann; da Silva, J. M. Hoff; Cindra, J. L.

2018-03-01

An exact solution of straight spinning cosmic strings in Brans-Dicke theory of gravitation is presented. The possibility of the existence of closed time-like curves around these cosmic strings is analyzed. Furthermore, the stability about the formation of the topological defect discussed here is checked. It is shown that the existence of a suitable choice for the integration constants in which closed time-like curves are not allowed. We also study the (im)possibility of using the obtained spacetime in the rotational curves problem.

Dialogue of Differences: The Writing of Henry Holmes Smith.

ERIC Educational Resources Information Center

Bossen, Howard

In addition to surveying the writings of Henry Holmes Smith, this paper explains his importance as a theoretician and practitioner of photography. After a discussion of Smith's ideas on "reading photographs" and his concerns with the ethics of photography, particularly of photojournalism, the essays in the book, "Henry Holmes Smith:…

Draft genome sequences of Streptococcus bovis strains ATCC 33317 and JB1

USDA-ARS?s Scientific Manuscript database

We report the draft genome sequences of Streptococcus bovis type strain ATTC 33317 (CVM42251) isolated from cow dung and strain JB1 (CVM42252) isolated from a cow rumen in 1977. Strains were subjected to Next Generation sequencing and the genome sizes are approximately 2 MB and 2.2 MB, respectively....

[Hypospadia and infertility of Henry II of France (1519-1559)].

PubMed

Hatzinger, M; Al-Shajlawi, S; Sohn, M

2014-03-01

Henry II (1519-1559) of France was the second son of Francis I (1494-1547) and Claude de France (1498-1524) born in 1519 in St. Germain-en-Laye. After his older brother's and his father's death in 1547, he was anointed the French king in Reims. In 1533 already, as a 14-year-old boy, for reasons of state, he was married to the same aged Catherine de Medici (1519-1589), as her uncle was Pope Clement VII (1478-1534). The marriage remained childless for 11 years since Henry, due to a distinct hypospadia and a completely sexually inexperienced wife was unable to conceive children with her. His existing liaison to Diane de Poitiers (1499-1566) - a 19-year-older maid of honor of his father Francis I from 1537 until his death - influenced his sexual life immensely.The blame for the childless marriage was placed primarily on his wife, as Henry had become father of an illegitimate daughter with a mistress. Catherine then underwent all possible medical and alchemical procedures to finally give birth to the hoped Dauphin. Ironically, her rival for the favor of her husband, Diane de Poitiers was one of her greatest allies. She made clear that the cause lay with Henry and not with his wife. This was confirmed by the added solid physician Jean Fernel (1497-1558). His treatment of Henry and the simultaneous training of the unexperienced Catherine by Diane de Poitiers led to success.The result was the birth of Francis II (1544-1560) in 1544, the first of 10 children in 12 years. Thus, the dynasty was saved. After the death of Henry in a tragic tournament accident in 1559, three of his sons became kings of France. But the line of Valois remained without further descendants and was continued by Henry IV, the first Bourbon king in 1589.

On the phenomenology of extended Brans-Dicke gravity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lima, Nelson A.; Ferreira, Pedro G., E-mail: ndal@roe.ac.uk, E-mail: p.ferreira1@physics.ox.ac.uk

We introduce a designer approach for extended Brans-Dicke gravity that allows us to obtain the evolution of the scalar field by fixing the Hubble parameter to that of a w CDM model. We obtain analytical approximations for ϕ as a function of the scale factor and use these to build expressions for the effective Newton's constant at the background and at the linear level and the slip between the perturbed Newtonian potentials. By doing so, we are able to explore their dependence on the fundamental parameters of the theory.

Teaching Students about the Environment with Henry David Thoreau

ERIC Educational Resources Information Center

Curriculum Review, 2008

2008-01-01

"Walden: The Ballad of Thoreau" is a two-act four-character play about the final two days writer Henry David Thoreau spent in his cabin before leaving Walden Pond. Teachers can use this play to teach about preserving the earth to students. This article presents a brief synopsis of the play and a brief biography of Henry David Thoreau.

Reserpine Inhibit the JB6 P+ Cell Transformation Through Epigenetic Reactivation of Nrf2-Mediated Anti-oxidative Stress Pathway.

PubMed

Hong, Bo; Su, Zhengyuan; Zhang, Chengyue; Yang, Yuqing; Guo, Yue; Li, Wenjing; Kong, Ah-Ng Tony

2016-05-01

Nuclear factor erythroid-2 related factor 2 (Nrf2) is a crucial transcription factor that regulates the expression of defensive antioxidants and detoxification enzymes in cells. In a previous study, we showed that expression of the Nrf2 gene is regulated by an epigenetic modification. Rauvolfia verticillata, a traditional Chinese herbal medicine widely used in China, possesses anticancer and antioxidant effects. In this study, we investigated how Nrf2 is epigenetically regulated by reserpine, the main active component in R. verticillata, in mouse skin epidermal JB6 P+ cells. Reserpine induced ARE (antioxidant response element)-luciferase activity in HepG2-C8 cells. Accordingly, in JB6 P+ cells, it upregulated the mRNA and protein levels of Nrf2 and its downstream target genes heme oxygenase-1 (HO-1) and quinone oxidoreductase 1 (NQO1), while it only increased the protein level of UDP-glucuronosyltransferase 1A1 (UGT1A1). Furthermore, reserpine decreased the TPA (12-O-tetradecanoylphorbol-13-acetate)-induced colony formation of JB6 cells in a dose-dependent manner. DNA sequencing and methylated DNA immunoprecipitation further demonstrated the demethylation effect of reserpine on the first 15 CpGs of the Nrf2 promoter in JB6 P+ cells. Reserpine also reduced the mRNA and protein expression of DNMT1 (DNA methyltransferase 1), DNMT3a (DNA methyltransferases 3a), and DNMT3b (DNA methyltransferases 3b). Moreover, reserpine induced Nrf2 expression via an epigenetic pathway in skin epidermal JB6 P+ cells, enhancing the protective antioxidant activity and decreasing TPA-induced cell transformation. These results suggest that reserpine exhibits a cancer preventive effect by reactivating Nrf2 and inducing the expression of target genes involved in cellular protection, potentially providing new insight into the chemoprevention of skin cancer using reserpine.

Henry Gray, plagiarist.

PubMed

Richardson, Ruth

2016-03-01

The first edition of Anatomy Descriptive and Surgical (1858) was greeted with accolades, but also provoked serious controversy concerning Henry Gray's failure to acknowledge the work of earlier anatomists. A review in the Medical Times (1859) accused Gray of intellectual theft. The journal took the unusual step of substantiating its indictment by publishing twenty parallel texts from Gray and from a pre-existing textbook, Quain's Anatomy. At the recent "Vesalius Continuum" conference in Zakynthos, Greece (2014) Professor Brion Benninger disputed the theft by announcing from the floor the results of a computer analysis of both texts, which he reported exonerated Gray by revealing no evidence of plagiarism. The analysis has not been forthcoming, however, despite requests. Here the historian of Gray's Anatomy supplements the argument set out in the Medical Times 150 years ago with data suggesting unwelcome personality traits in Henry Gray, and demonstrating the utility of others' work to his professional advancement. Fair dealing in the world of anatomy and indeed the genuineness of the lustre of medical fame are important matters, but whether quantitative evidence has anything to add to the discussion concerning Gray's probity can be assessed only if Benninger makes public his computer analysis. © 2015 Wiley Periodicals, Inc.

Thiamin

MedlinePlus

... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Riboflavin

MedlinePlus

... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Vitamin B12

MedlinePlus

... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Vitamin D

MedlinePlus

... 25419853 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Accessed May 5, 2017. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Vitamin K

MedlinePlus

... 25057538 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Zinc in diet

MedlinePlus

... 25077263 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Niacin

MedlinePlus

... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Vitamin B6

MedlinePlus

... 23193625 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Vitamin E

MedlinePlus

... 25077263 . Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Beta-carotene blood test

MedlinePlus

... 302. Mason JB. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Saunders; 2016:chap 218. Salwen MJ. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical ...

Copper and dyes enhance laccase production in gamma-proteobacterium JB.

PubMed

Malhotra, Kanam; Sharma, Prince; Capalash, Neena

2004-07-01

Laccase production in gamma-proteobacterium JB was enhanced 13-fold by adding 0.1 mM CuSO(4) 24 h after the onset of growth. Ethidium bromide (2.5 microM), Malachite Green, Phenol Red and Thymol Blue (10 microM each) enhanced laccase production 17-, 19-, 4- and 2-fold, respectively. Among the fourteen aromatic/organic compounds tried, p-aminobenzoic acid and an industrial effluent, from where the organism was isolated, showed 1.2- and 1.26-fold increases in production.

Exact solutions to Brans-Dicke cosmologies in flat Friedmann universes.

NASA Technical Reports Server (NTRS)

Morganstern, R. E.

1971-01-01

The Brans-Dicke cosmological equations for flat Friedmann-type expanding universes are solved parametrically for time, density, expansion parameter, and scalar field. These results reduce to a previously obtained exact solution to the radiation cosmology. Although the scalar field may be undetectable at the present epoch, it is felt that, if it exists, it must play an important role as one approaches the initial singularity of the cosmology.

Local distinguishability of Dicke states in quantum secret sharing

NASA Astrophysics Data System (ADS)

Wang, Jing-Tao; Xu, Gang; Chen, Xiu-Bo; Sun, Xing-Ming; Jia, Heng-Yue

2017-03-01

We comprehensively investigate the local distinguishability of orthogonal Dicke states under local operations and classical communication (LOCC) from both qualitative and quantitative aspects. Based on our work, defects in the LOCC-quantum secret sharing (QSS) scheme can be complemented, and the information leakage can be quantified. For (k1 ,k2 , k , n)-threshold LOCC-QSS scheme, more intuitive formulas for unambiguous probability and guessing probability were established, which can be used for determining the parameter k1 and k2 directly.

Lactobacillus rhamnosus strain JB-1 reverses restraint stress-induced gut dysmotility.

PubMed

West, C; Wu, R Y; Wong, A; Stanisz, A M; Yan, R; Min, K K; Pasyk, M; McVey Neufeld, K-A; Karamat, M I; Foster, J A; Bienenstock, J; Forsythe, P; Kunze, W A

2017-01-01

Environmental stress affects the gut with dysmotility being a common consequence. Although a variety of microbes or molecules may prevent the dysmotility, none reverse the dysmotility. We have used a 1 hour restraint stress mouse model to test for treatment effects of the neuroactive microbe, L. rhamnosus JB-1 ™ . Motility of fluid-filled ex vivo gut segments in a perfusion organ bath was recorded by video and migrating motor complexes measured using spatiotemporal maps of diameter changes. Stress reduced jejunal and increased colonic propagating contractile cluster velocities and frequencies, while increasing contraction amplitudes for both. Luminal application of 10E8 cfu/mL JB-1 restored motor complex variables to unstressed levels within minutes of application. L. salivarius or Na.acetate had no treatment effects, while Na.butyrate partially reversed stress effects on colonic frequency and amplitude. Na.propionate reversed the stress effects for jejunum and colon except on jejunal amplitude. Our findings demonstrate, for the first time, a potential for certain beneficial microbes as treatment of stress-induced intestinal dysmotility and that the mechanism for restoration of function occurs within the intestine via a rapid drug-like action on the enteric nervous system. © 2016 John Wiley & Sons Ltd.

Arbitrary Dicke-State Control of Symmetric Rydberg Ensembles

NASA Astrophysics Data System (ADS)

Deutsch, Ivan

2017-04-01

We study the production of arbitrary superpositions of Dicke states via optimal control. We show that N atomic hyperfine qubits, interacting symmetrically via the Rydberg blockade, are well described by the Jaynes-Cummings Model (JCM), familiar in cavity QED. In this isomorphism, the presence or absence of a collective Rydberg excitation plays the role of the two-level system and the number of symmetric excitations of the hyperfine qubits plays the role of the bosonic excitations of the JCM. This system is fully controllable through the addition of phase-modulated microwaves that drive transitions between the Rydberg-dressed states. In the weak dressing regime, this results in a single-axis twisting Hamiltonian, plus time-dependent rotations of the collective spin. For strong dressing we control the entire Jaynes-Cummings ladder. Using optimal control, we design microwave waveforms that can generate arbitrary states in the symmetric subspace. This includes cat states, Dicke states, and spin squeezed states. With currently feasible parameters, it is possible to generate arbitrary symmetric states of _10 hyperfine qubits in 1 microsec, assuming a fast microwave phase switching time. The same control can be achieved with a ``dressed-ground control'' scheme, which reduces the demands for fast phase switching at the expense of increased total control time. More generally, we can achieve control on larger ensembles of qubits by designing waveforms that are bandwidth limited within the coherence time of the system. We use this to study general questions of the ``quantum speed limit'' and information content in a waveform that is needed to generate arbitrary quantum states.

75 FR 21288 - Henry Gas Storage LLC; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-23

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP10-125-000] Henry Gas Storage LLC; Notice of Application April 16, 2010. Take notice that on April 5, 2010, Henry Gas Storage... developing the Cote Blanche Island salt dome for natural gas storage in St. Mary Parish, Louisiana, all as...

Digital-analog quantum simulation of generalized Dicke models with superconducting circuits

NASA Astrophysics Data System (ADS)

Lamata, Lucas

2017-03-01

We propose a digital-analog quantum simulation of generalized Dicke models with superconducting circuits, including Fermi- Bose condensates, biased and pulsed Dicke models, for all regimes of light-matter coupling. We encode these classes of problems in a set of superconducting qubits coupled with a bosonic mode implemented by a transmission line resonator. Via digital-analog techniques, an efficient quantum simulation can be performed in state-of-the-art circuit quantum electrodynamics platforms, by suitable decomposition into analog qubit-bosonic blocks and collective single-qubit pulses through digital steps. Moreover, just a single global analog block would be needed during the whole protocol in most of the cases, superimposed with fast periodic pulses to rotate and detune the qubits. Therefore, a large number of digital steps may be attained with this approach, providing a reduced digital error. Additionally, the number of gates per digital step does not grow with the number of qubits, rendering the simulation efficient. This strategy paves the way for the scalable digital-analog quantum simulation of many-body dynamics involving bosonic modes and spin degrees of freedom with superconducting circuits.

Digital-analog quantum simulation of generalized Dicke models with superconducting circuits

PubMed Central

Lamata, Lucas

2017-01-01

We propose a digital-analog quantum simulation of generalized Dicke models with superconducting circuits, including Fermi- Bose condensates, biased and pulsed Dicke models, for all regimes of light-matter coupling. We encode these classes of problems in a set of superconducting qubits coupled with a bosonic mode implemented by a transmission line resonator. Via digital-analog techniques, an efficient quantum simulation can be performed in state-of-the-art circuit quantum electrodynamics platforms, by suitable decomposition into analog qubit-bosonic blocks and collective single-qubit pulses through digital steps. Moreover, just a single global analog block would be needed during the whole protocol in most of the cases, superimposed with fast periodic pulses to rotate and detune the qubits. Therefore, a large number of digital steps may be attained with this approach, providing a reduced digital error. Additionally, the number of gates per digital step does not grow with the number of qubits, rendering the simulation efficient. This strategy paves the way for the scalable digital-analog quantum simulation of many-body dynamics involving bosonic modes and spin degrees of freedom with superconducting circuits. PMID:28256559

Effects of anisotropy on interacting ghost dark energy in Brans-Dicke theories

NASA Astrophysics Data System (ADS)

Hossienkhani, H.; Fayaz, V.; Azimi, N.

2017-03-01

In this work we concentrate on the ghost dark energy model within the framework of the Brans-Dicke theory in an anisotropic Universe. Within this framework we discuss the behavior of equation of state, deceleration and dark energy density parameters of the model. We consider the squared sound speed and quest for signs of stability of the model. We also probe observational constraints by using the latest observational data on the ghost dark energy models as the unification of dark matter and dark energy. In order to do so, we focus on observational determinations of the Hubble expansion rate (namely, the expansion history) H(z). Then we evaluate the evolution of the growth of perturbations in the linear regime for both ghost DE and Brans-Dicke theory and compare the results with standard FRW and ΛCDM models. We display the effects of the anisotropy on the evolutionary behavior the ghost DE models where the growth rate is higher in this models. Eventually the growth factor for the ΛCDM Universe will always fall behind the ghost DE models in an anisotropic Universe.

Metallic Nickel Nanoparticles May Exhibit Higher Carcinogenic Potential than Fine Particles in JB6 Cells

PubMed Central

Bowman, Linda; Zou, Baobo; Mao, Guochuan; Xu, Jin; Castranova, Vincent; Zhao, Jinshun; Ding, Min

2014-01-01

While numerous studies have described the pathogenic and carcinogenic effects of nickel compounds, little has been done on the biological effects of metallic nickel. Moreover, the carcinogenetic potential of metallic nickel nanoparticles is unknown. Activator protein-1 (AP-1) and nuclear factor-κB (NF-κB) have been shown to play pivotal roles in tumor initiation, promotion, and progression. Mutation of the p53 tumor suppressor gene is considered to be one of the steps leading to the neoplastic state. The present study examines effects of metallic nickel fine and nanoparticles on tumor promoter or suppressor gene expressions as well as on cell transformation in JB6 cells. Our results demonstrate that metallic nickel nanoparticles caused higher activation of AP-1 and NF-κB, and a greater decrease of p53 transcription activity than fine particles. Western blot indicates that metallic nickel nanoparticles induced a higher level of protein expressions for R-Ras, c-myc, C-Jun, p65, and p50 in a time-dependent manner. In addition, both metallic nickel nano- and fine particles increased anchorage-independent colony formation in JB6 P+ cells in the soft agar assay. These results imply that metallic nickel fine and nanoparticles are both carcinogenetic in vitro in JB6 cells. Moreover, metallic nickel nanoparticles may exhibit higher carcinogenic potential, which suggests that precautionary measures should be taken in the use of nickel nanoparticles or its compounds in nanomedicine. PMID:24691273

Xenobiotics enhance laccase activity in alkali-tolerant γ-proteobacterium JB.

PubMed

Singh, Gursharan; Batish, Mona; Sharma, Prince; Capalash, Neena

2009-01-01

Various genotoxic textile dyes, xenobiotics, substrates (10 µM) and agrochemicals (100 µg/ml) were tested for enhancement of alkalophilic laccase activity in γ-proteobacterium JB. Neutral Red, Indigo Carmine, Naphthol Base Bordears and Sulphast Ruby dyes increased the activity by 3.7, 2.7, 2.6 and 2.3 fold respectively. Xenobiotics/substrates like p-toluidine, 8-hydroxyquinoline and anthracine increased it by 3.4, 2.8 and 2.3 fold respectively. Atrazine and trycyclozole pesticides enhanced the activity by 1.95 and 1.5 fold respectively.

Xenobiotics enhance laccase activity in alkali-tolerant γ-proteobacterium JB

PubMed Central

Singh, Gursharan; Batish, Mona; Sharma, Prince; Capalash, Neena

2009-01-01

Various genotoxic textile dyes, xenobiotics, substrates (10 µM) and agrochemicals (100 µg/ml) were tested for enhancement of alkalophilic laccase activity in γ-proteobacterium JB. Neutral Red, Indigo Carmine, Naphthol Base Bordears and Sulphast Ruby dyes increased the activity by 3.7, 2.7, 2.6 and 2.3 fold respectively. Xenobiotics/substrates like p-toluidine, 8-hydroxyquinoline and anthracine increased it by 3.4, 2.8 and 2.3 fold respectively. Atrazine and trycyclozole pesticides enhanced the activity by 1.95 and 1.5 fold respectively. PMID:24031313

The Rice University Press Initiative: An Interview with Charles Henry

ERIC Educational Resources Information Center

Trevitte, Chad; Henry, Charles

2007-01-01

In this interview Charles Henry, publisher of the Rice University Press (RUP), discusses RUP's rebirth as a fully digital university press. Henry addresses the circumstances that led to this decision, and he further outlines the RUP business model whereby the press will publish its own titles--both digitally and in print-on-demand--while…

West Harlem Walk (Hudson River Valley Greenway) beneath Henry Hudson ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

West Harlem Walk (Hudson River Valley Greenway) beneath Henry Hudson Parkway (HHP) Viaduct at West 155th Street vicinity, with Palisades, George Washington Bridge, and Little Red Lighthouse (visible to left of bridge tower) in background, looking northeast. - Henry Hudson Parkway, Extending 11.2 miles from West 72nd Street to Bronx-Westchester border, New York County, NY

Henry's voices: the representation of auditory verbal hallucinations in an autobiographical narrative.

PubMed

Demjén, Zsófia; Semino, Elena

2015-06-01

The book Henry's Demons (2011) recounts the events surrounding Henry Cockburn's diagnosis of schizophrenia from the alternating perspectives of Henry himself and his father Patrick. In this paper, we present a detailed linguistic analysis of Henry's first-person accounts of experiences that could be described as auditory verbal hallucinations. We first provide a typology of Henry's voices, taking into account who or what is presented as speaking, what kinds of utterances they produce and any salient stylistic features of these utterances. We then discuss the linguistically distinctive ways in which Henry represents these voices in his narrative. We focus on the use of Direct Speech as opposed to other forms of speech presentation, the use of the sensory verbs hear and feel and the use of 'non-factive' expressions such as I thought and as if. We show how different linguistic representations may suggest phenomenological differences between the experience of hallucinatory voices and the perception of voices that other people can also hear. We, therefore, propose that linguistic analysis is ideally placed to provide in-depth accounts of the phenomenology of voice hearing and point out the implications of this approach for clinical practice and mental healthcare. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Modulation of JB6 Mouse Epidermal Cell Transformation Response by the Prostaglandin F2 Alpha Receptor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weber, Thomas J.; Markillie, Lye MENG.; Chrisler, William B.

2002-12-01

Prostaglandin F2a (PGF2a) has been associated with the modulation of clonal selection processes in the mouse skin model of carcinogenesis. We have investigated whether JB6 mouse epidermal cells express a functional PGF2a receptor (FP) coupled to the regulation of anchorage-dependent and -independent growth. Treatment of JB6 cells with a FP receptor ligand (fluprostenol) potently (pM-nM) increased anchorage-dependent and -independent growth, as determined by a battery of in vitro assays. Treatment of JB6 cells with PGF2a and fluprostenol increased inositol phospholipid accumulation and extracellular signal regulated kinase (ERK) activity, consistent with FP receptor-related signaling. FP receptor mRNA was detected by reversemore » transcription-polymerase chain reaction and a radiolabel binding assay determined the average specific [3H]PGF2a binding to be 8.25 + 0.95 fmol/mg protein. Treatment of cells with fluprostenol as a single exposure resulted in a significant increase in anchorage-dependent and -independent growth in media containing low (0.1-0.5%), but not high (5%) concentrations of fetal bovine serum (FBS). In contrast, treatment of cells with fluprostenol at two day intervals resulted in a more robust growth response under anchorage-dependent conditions only in media containing low FBS concentrations; and under anchorage-independent conditions only in media containing high FBS concentrations. ERK activation and colony size were increased by cotreatment of JB6 cells with EGF and fluprostenol to a greater extent than either treatment alone, while the cotreatment effect on colony number appeared to be simply additive. In summary, FBS concentration and signal oscillation exert pronounced effects on the biological response to a FP receptor agonist. The data raise the possibility that the FP receptor may independently contribute to clonal selection processes, but may play a more important role as a response modifier.« less

A Henry's Law Test for Experimental Partitioning Studies of Iron Meteorites

NASA Technical Reports Server (NTRS)

Chabot, N. L.; Campbell, A. J.; Humayun, M.; Agee, C. B.

2001-01-01

Low-level doped solid metal/liquid metal experiments analyzed by laser ablation ICP-MS allow Henry's Law to be tested. The results indicate Henry's Law is obeyed and the experimental partition coefficients can be applied to iron meteorites. Additional information is contained in the original extended abstract.

W.E. Henry Symposium compendium: The importance of magnetism in physics and material science

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carwell, H.

This compendium contains papers presented at the W. E. Henry Symposium, The Importance of Magnetism in Physics and Material Science. The one-day symposium was conducted to recognize the achievements of Dr. Warren Elliot Henry as educator, scientist, and inventor in a career spanning almost 70 years. Dr. Henry, who is 88 years old, attended the symposium. Nobel Laureate, Dr. Glenn Seaborg, a friend and colleague for over 40 years, attended the event and shared his personal reminiscences. Dr. Seaborg is Associate Director-At-Large at the Lawrence Berkeley National Laboratory. The Compendium begins with three papers which demonstrate the ongoing importance ofmore » magnetism in physics and material science. Other contributions cover the highlights of Dr. Henry`s career as a researcher, educator, and inventor. Colleagues and former students share insights on the impact of Dr. Henry`s research in the field of magnetism, low temperature physics, and solid state physics; his influence on students as an educator; and his character, intellect and ingenuity, and passion for learning and teaching. They share a glimpse of the environment and times that molded him as a man, and the circumstances under which he made his great achievements despite the many challenges he faced.« less

15. Historic American Buildings Survey. Plan of Fort McHenry, by ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Historic American Buildings Survey. Plan of Fort McHenry, by William Tell Poussin, 1819. National Archives, Records of the War Department, Cartographic Section, Record Group 77, drawer 51, sheet 2. - Fort McHenry National Monument & Historic Shrine, East Fort Avenue at Whetstone Point, Baltimore, Independent City, MD

BOOK REVIEW: Joseph Henry: The Rise of an American Scientist

NASA Astrophysics Data System (ADS)

Crawford, Elspeth

1998-09-01

Albert Moyer has clearly done his research into the events of Joseph Henry's life. The personal, professional, sociological and scientific aspects have been meticulously detailed throughout and the ordering, as in the chapter headings, is chronological, so that there is some element of each of these aspects in each chapter. This is unfortunately both the strength and the weakness of the biography, as the detail seemed to me to be the most remarkable characteristic of the writing. But, the bigger stories, or the themes, which might have been possible, seemed to get lost. Hence, I found this a book for those who are seriously interested in Joseph Henry; but for those whose interest might be more general, say having an interest in nineteenth century growth of scientific institutions, or wanting to understand the conceptual development of electromagnetism, there seemed to be too much which came from the Henry point of view, rather than locating Henry within his time and context. This is a remark about style, rather than omission of content, as the myriad of details in each paragraph certainly inform the reader about the context. For instance, some sociology of the USA in the nineteenth century could be inferred, say showing how a young man from a modest background might make his way into a professional life, but the information is so particularly a description of Henry's experience that one has to rely on prior knowledge or make assumptions in order to create a sociological perspective. That is, I now know, what happened to Henry, but I do not know if his case was in any sense typical or atypical. Similarly there is information about education in general at that time, and scientific education, research and its publication, as it applied to Henry. The relationships between science in the USA and in Europe have a place, and there is quite a bit of information about the institutions in which Henry worked, particularly Albany Academy, Princeton and the Smithsonian. Henry

Fort McHenry alternative transportation study

DOT National Transportation Integrated Search

2004-06-01

This project assesses transportation management issues at Fort McHenry National Monument and Historic Shrine in the Locust Point area of Baltimore. Goals of the study include mitigating traffic congestion and idling of school or tour buses, encouragi...

Teaching Psychology and Literature: Melancholia as Motivation in the Novels of Dick Francis

ERIC Educational Resources Information Center

Wagner, Elaine

2010-01-01

Teaching literature from a psychological perspective provides a basis for the study and analysis of human motivation and behavior, as psychology and literature make mutual contributions to the study of both disciplines. Melancholia is a recurring theme in the novels of Dick Francis, and the first-person accounts of despair and depression are…

Taxifolin Activates the Nrf2 Anti-Oxidative Stress Pathway in Mouse Skin Epidermal JB6 P+ Cells through Epigenetic Modifications

PubMed Central

Kuang, Haixue; Tang, Zhenqiu; Zhang, Chengyue; Wang, Zhibin; Li, Wenji; Yang, Chunjuan; Wang, Qiuhong; Yang, Bingyou; Kong, Ah-Ng

2017-01-01

Nuclear factor erythroid-2 related factor 2 (Nrf2) is a vital transcription factor that regulates the anti-oxidative defense system. Previous reports suggested that the expression of the Nrf2 gene can be regulated by epigenetic modifications. The potential epigenetic effect of taxifolin (TAX), a potent cancer chemopreventive agent, in skin cancer chemoprotection is unknown. In this study, we investigated how Nrf2 is epigenetically regulated by TAX in JB6 P+ cells. TAX was found to inhibit the 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced colony formation of JB6 P+ cells. TAX induced antioxidant response element (ARE)-luciferase activity in HepG2-C8 cells and up-regulated mRNA and protein levels of Nrf2 and its downstream genes heme oxygenase-1 (HO-1) and NAD(P)H quinone oxidoreductase 1 (NQO1), in JB6 P+ cells. Furthermore, bisulfite genomic sequencing revealed that TAX treatment reduces the methylation level of the first 15 CpGs sites in the Nrf2 promoter. Western blotting showed that TAX inhibits the expression levels of DNA methyltransferase (DNMT) and histone deacetylase (HDAC) proteins. In summary, our results revealed that TAX can induce expression of Nrf2 and its downstream target genes in JB6 P+ cells by CpG demethylation. These finding suggest that TAX may exhibit a skin cancer preventive effect by activating Nrf2 via an epigenetic pathway. PMID:28714938

Tablet PCs in Engineering Mathematics Courses at the J.B. Speed School of Engineering

ERIC Educational Resources Information Center

Hieb, Jeffrey L.; Ralston, Patricia A. S.

2010-01-01

In fall 2007, J.B. Speed School of Engineering at the University of Louisville joined the ranks of universities requiring the purchase of Tablet PCs for all new entering students. This article presents a description of how the Department of Engineering Fundamentals incorporated Tablet PCs into their instruction, a review of the literature…

Dynamics of cosmological perturbations in modified Brans-Dicke cosmology with matter-scalar field interaction

NASA Astrophysics Data System (ADS)

Kofinas, Georgios; Lima, Nelson A.

2017-10-01

In this work we focus on a novel completion of the well-known Brans-Dicke theory that introduces an interaction between the dark energy and dark matter sectors, known as complete Brans-Dicke (CBD) theory. We obtain viable cosmological accelerating solutions that fit supernovae observations with great precision without any scalar potential V (ϕ ). We use these solutions to explore the impact of the CBD theory on the large scale structure by studying the dynamics of its linear perturbations. We observe a growing behavior of the lensing potential Φ+ at late-times, while the growth rate is actually suppressed relatively to Λ CDM , which allows the CBD theory to provide a competitive fit to current RSD measurements of f σ8. However, we also observe that the theory exhibits a pathological change of sign in the effective gravitational constant concerning the perturbations on subhorizon scales that could pose a challenge to its validity.

Should bulk cloudwater or fogwater samples obey Henry's law?

NASA Astrophysics Data System (ADS)

Pandis, Spyros N.; Seinfeld, John H.

1991-06-01

Mixing of droplets with different pH that are individually in Henry's law equilibrium with the surrounding atmosphere always results in a bulk mixture that is supersaturated with weak acids like S(IV) and HCOOH, and bases like NH3 with respect to the original atmosphere. High supersaturations result only when the pH of the bulk droplet mixture exceeds the pKa of the species, in which pH range large pH differences among droplets of different sizes lead to large deviations from Henry's law for the bulk mixture. The deviation is shown to depend on the ratio of the arithmetic mean to the harmonic mean of the hydrogen ion concentrations of the droplets with the liquid water content used as weighting factor in the calculation of the means. The theory developed can explain observed discrepancies from Henry's law in atmospheric samples and also other observed phenomena like the reported increase of pH values of bulk aqueous samples during storage.

Who was... John Henri Fabre?

PubMed

Malcolm, Alan D B

2002-04-01

The books of Jean Henri Fabre, replete with lively accounts of his observations on nature, inspired generations of children from all over the world. The detail in his study of insects and the entertaining presentation allowed readers to absorb his fascination. Yet, he was a physics teacher by profession and virtually self taught on matters of entomology.

Bioremediation of Petrochemical Wastewater Containing BTEX Compounds by a New Immobilized Bacterium Comamonas sp. JB in Magnetic Gellan Gum.

PubMed

Jiang, Bei; Zhou, Zunchun; Dong, Ying; Wang, Bai; Jiang, Jingwei; Guan, Xiaoyan; Gao, Shan; Yang, Aifu; Chen, Zhong; Sun, Hongjuan

2015-05-01

In this study, we investigated the bioremediation of petrochemical wastewater containing BTEX compounds by immobilized Comamonas sp. JB cells. Three kinds of magnetic nanoparticles were evaluated as immobilization supports for strain JB. After comparison with Fe3O4 and a-Fe2O3 nanoparticles, r-Fe2O3 nanoparticle was selected as the optimal immobilization support. The highest biodegradation activity of r-Fe2O3-magnetically immobilized cells was obtained when the concentration of r-Fe2O3 nanoparticle was 120 mg L(-1). Additionally, the recycling experiments demonstrated that the degradation activity of r-Fe2O3-magnetically immobilized cells was still high and led to less toxicity than untreated wastewater during the eight recycles. qPCR suggested the concentration of strain JB in r-Fe2O3-magnetically immobilized cells was evidently increased after eight cycles of degradation experiments. These results supported developing efficient biocatalysts using r-Fe2O3-magnetically immobilized cells and provided a promising technique for improving biocatalysts used in the bioremediation of not only petrochemical wastewater but also other hazardous wastewater.

Solute and heat transport model of the Henry and Hilleke laboratory experiment

USGS Publications Warehouse

Langevin, C.D.; Dausman, A.M.; Sukop, M.C.

2010-01-01

SEAWAT is a coupled version of MODFLOW and MT3DMS designed to simulate variable-density ground water flow and solute transport. The most recent version of SEAWAT, called SEAWAT Version 4, includes new capabilities to represent simultaneous multispecies solute and heat transport. To test the new features in SEAWAT, the laboratory experiment of Henry and Hilleke (1972) was simulated. Henry and Hilleke used warm fresh water to recharge a large sand-filled glass tank. A cold salt water boundary was represented on one side. Adjustable heating pads were used to heat the bottom and left sides of the tank. In the laboratory experiment, Henry and Hilleke observed both salt water and fresh water flow systems separated by a narrow transition zone. After minor tuning of several input parameters with a parameter estimation program, results from the SEAWAT simulation show good agreement with the experiment. SEAWAT results suggest that heat loss to the room was more than expected by Henry and Hilleke, and that multiple thermal convection cells are the likely cause of the widened transition zone near the hot end of the tank. Other computer programs with similar capabilities may benefit from benchmark testing with the Henry and Hilleke laboratory experiment. Journal Compilation ?? 2009 National Ground Water Association.

Henry Giroux on Democracy Unsettled: From Critical Pedagogy to the War on Youth--An Interview

ERIC Educational Resources Information Center

Peters, Michael A.

2012-01-01

This interview conducted with Henry Giroux begins by probing Henry's childhood, upbringing and undergraduate years to discover where his sense of social justice took hold. It also questions Henry about his working-class background and the major influences on his thought, including his relationships with Paulo Freire and Howard Zinn. The interview…

The medical life of Henry Norman Bethune

PubMed Central

Deslauriers, Jean; Goulet, Denis

2015-01-01

BACKGROUND: Henry Norman Bethune is one of the most exciting and incredible surgeons that Canada has ever produced. Indeed, he is often characterized as one of the world’s best-known surgeons. He was an innovator and his scientific contributions have stood the test of time. In Canada, he will forever be remembered as a social activist committed to the welfare of the poor and to the reform of the health care system. In the People’s Republic of China, he is idolized and remains the only foreigner to ever become a national hero. OBJECTIVE: To detail the numerous and significant achievements of Henry Norman Bethune in the field of thoracic surgery and as a social activist and describe his heroic war-time actions on the battlefields of both Spain and China. METHOD: Information was gathered through the reading of the numerous publications written about the life and work of Bethune, interviews with knowledgeable people from Canadian and Chinese universities, analysis of Bethune’s own publications, and extensive experience of one of the authors in China. RESULTS: In the social sense, Henry Norman Bethune had a difficult personality, but he was deeply caring about the plight of his patients, especially the poor. As a thoracic surgeon, he could be ingenious, thoughtful and effective but he could also be abrasive, restless and temperamental. His scientific contributions were sound and, at the time, gained worldwide attention. As an activist, he led a crusade to reform the Canadian health care system, demanding free health care for all. His outstanding work during the Spanish Civil War, where he organized the first ever mobile blood transfusion unit, and during the Sino-Japanese war, where he was totally committed to the welfare of both soldiers and civilian population, were deliberate acts of resistance against Fascist onslaught and enthusiasm for the Communist cause. CONCLUSIONS: Henry Norman Bethune was unconventional and a revolutionary, but he was brilliant. He will

46 CFR 7.55 - Cape Henry, VA to Cape Fear, NC.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Cape Henry, VA to Cape Fear, NC. 7.55 Section 7.55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.55 Cape Henry, VA to Cape Fear, NC. (a) A line drawn from Rudee Inlet Jetty Light “2” to...

Digital-analog quantum simulation of generalized Dicke models with superconducting circuits

NASA Astrophysics Data System (ADS)

Lamata, Lucas

We propose a digital-analog quantum simulation of generalized Dicke models with superconducting circuits, including Fermi-Bose condensates, biased and pulsed Dicke models, for all regimes of light-matter coupling. We encode these classes of problems in a set of superconducting qubits coupled with a bosonic mode implemented by a transmission line resonator. Via digital-analog techniques, an efficient quantum simulation can be performed in state-of-the-art circuit quantum electrodynamics platforms, by suitable decomposition into analog qubit-bosonic blocks and collective single-qubit pulses through digital steps. Moreover, just a single global analog block would be needed during the whole protocol in most of the cases, superimposed with fast periodic pulses to rotate and detune the qubits. Therefore, a large number of digital steps may be attained with this approach, providing a reduced digital error. Additionally, the number of gates per digital step does not grow with the number of qubits, rendering the simulation efficient. This strategy paves the way for the scalable digital-analog quantum simulation of many-body dynamics involving bosonic modes and spin degrees of freedom with superconducting circuits. The author wishes to acknowledge discussions with I. Arrazola, A. Mezzacapo, J. S. Pedernales, and E. Solano, and support from Ramon y Cajal Grant RYC-2012-11391, Spanish MINECO/FEDER FIS2015-69983-P, UPV/EHU UFI 11/55 and Project EHUA14/04.

Gravitational field of a concentrated mass in Jordan—Brans—Dicke theory

NASA Astrophysics Data System (ADS)

Arutyunyan, G. G.; Papoyan, V. V.

1994-04-01

The problem of determining the gravitational field of a static, spherically symmetric, self-gravitating object is formulated. The small number of physically applicable exact solutions of the equations in Jordan—Brans—Dicke theory is augmented with new exact solutions describing the external gravitational field of the given body. Once a solution has been found, it can be rewritten in modified curvature, homogeneous, and other coordinates by appropriate gauging. In a special case the solution coincides with the well-known Schwarzschild solution.

American Chemical Society division of fuel chemistry Henry H. Storch award.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chemistry

American Chemical Society Division of Fuel Chemistry Henry H. Storch Award ... The purpose of the Henry H. Storch Award is to recognize distinguished contributions worldwide to fundamental or engineering research on the chemistry and utilization of all hydrocarbon fuels, with the exception of petroleum. ... The award was established in 1964 by the American Chemical Society Division of Fuel Chemistry and administered by the Division until 1985.

Anisotropic string cosmological model in Brans–Dicke theory of gravitation with time-dependent deceleration parameter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maurya, D. Ch., E-mail: dcmaurya563@gmail.com; Zia, R., E-mail: rashidzya@gmail.com; Pradhan, A., E-mail: pradhan.anirudh@gmail.com

We discuss a spatially homogeneous and anisotropic string cosmological models in the Brans–Dicke theory of gravitation. For a spatially homogeneous metric, it is assumed that the expansion scalar θ is proportional to the shear scalar σ. This condition leads to A = kB{sup m}, where k and m are constants. With these assumptions and also assuming a variable scale factor a = a(t), we find solutions of the Brans–Dicke field equations. Various phenomena like the Big Bang, expanding universe, and shift from anisotropy to isotropy are observed in the model. It can also be seen that in early stage ofmore » the evolution of the universe, strings dominate over particles, whereas the universe is dominated by massive strings at the late time. Some physical and geometrical behaviors of the models are also discussed and observed to be in good agreement with the recent observations of SNe la supernovae.« less

First-Order Quantum Phase Transition for Dicke Model Induced by Atom-Atom Interaction

NASA Astrophysics Data System (ADS)

Zhao, Xiu-Qin; Liu, Ni; Liang, Jiu-Qing

2017-05-01

In this article, we use the spin coherent state transformation and the ground state variational method to theoretically calculate the ground function. In order to consider the influence of the atom-atom interaction on the extended Dicke model’s ground state properties, the mean photon number, the scaled atomic population and the average ground energy are displayed. Using the self-consistent field theory to solve the atom-atom interaction, we discover the system undergoes a first-order quantum phase transition from the normal phase to the superradiant phase, but a famous Dicke-type second-order quantum phase transition without the atom-atom interaction. Meanwhile, the atom-atom interaction makes the phase transition point shift to the lower atom-photon collective coupling strength. Supported by the National Natural Science Foundation of China under Grant Nos. 11275118, 11404198, 91430109, 61505100, 51502189, and the Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi Province (STIP) under Grant No. 2014102, and the Launch of the Scientific Research of Shanxi University under Grant No. 011151801004, and the National Fundamental Fund of Personnel Training under Grant No. J1103210. The Natural Science Foundation of Shanxi Province under Grant No. 2015011008

Holographic Dark Energy in Brans-Dicke Theory with Logarithmic Form of Scalar Field

NASA Astrophysics Data System (ADS)

Singh, C. P.; Kumar, Pankaj

2017-10-01

In this paper, an interacting holographic dark energy model with Hubble horizon as an infra-red cut-off is considered in the framework of Brans-Dicke theory. We assume the Brans-Dicke scalar field as a logarithmic form ϕ = ϕ 0 l n( α + β a), where a is the scale factor, α and β are arbitrary constants, to interpret the physical phenomena of the Universe. The equation of state parameter w h and deceleration parameter q are obtained to discuss the dynamics of the evolution of the Universe. We present a unified model of holographic dark energy which explains the early time acceleration (inflation), medieval time deceleration and late time acceleration. It is also observed that w h may cross the phantom divide line in the late time evolution. We also discuss the cosmic coincidence problem. We obtain a time-varying density ratio of holographic dark energy to dark matter which is a constant of order one (r˜ O(1)) during early and late time evolution, and may evolve sufficiently slow at present time. Thus, the model successfully resolves the cosmic coincidence problem.

First-order dipolar phase transition in the Dicke model with infinitely coordinated frustrating interaction

NASA Astrophysics Data System (ADS)

Mukhin, S. I.; Gnezdilov, N. V.

2018-05-01

We found analytically a first-order quantum phase transition in a Cooper pair box array of N low-capacitance Josephson junctions capacitively coupled to resonant photons in a microwave cavity. The Hamiltonian of the system maps on the extended Dicke Hamiltonian of N spins 1 /2 with infinitely coordinated antiferromagnetic (frustrating) interaction. This interaction arises from the gauge-invariant coupling of the Josephson-junction phases to the vector potential of the resonant photons field. In the N ≫1 semiclassical limit, we found a critical coupling at which the ground state of the system switches to one with a net collective electric dipole moment of the Cooper pair boxes coupled to a super-radiant equilibrium photonic condensate. This phase transition changes from the first to second order if the frustrating interaction is switched off. A self-consistently "rotating" Holstein-Primakoff representation for the Cartesian components of the total superspin is proposed, that enables one to trace both the first- and the second-order quantum phase transitions in the extended and standard Dicke models, respectively.

Involvement of the antioxidative property of morusin in blocking phorbol ester-induced malignant transformation of JB6 P+ mouse epidermal cells.

PubMed

Cheng, Pai-Shan; Hu, Chao-Chin; Wang, Chau-Jong; Lee, Yean-Jang; Chung, Wei-Chia; Tseng, Tsui-Hwa

2017-02-25

Chemoprevention has been acknowledged as an important and practical strategy for managing cancer. We have previously synthesized morusin, a prenylated flavonoid that exhibits anti-cancer progression activity. In the present study, we evaluated the anti-cancer promotion potential of morusin by using the mouse epidermal JB6 P + cell model. Extensive evidence shows that tumor promotion by phorbol esters is due to the stimulation of reactive oxygen species (ROS). Therefore, the effect of morusin on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ROS production was assessed. Noncytotoxic concentrations of morusin were found to dose-dependently reduce TPA-induced ROS production. Moreover, morusin inhibited TPA-induced activator protein-1 (AP-1) and nuclear factor-kappa B (NF-κB) activation, which can mediate cell proliferation and malignant transformation. Furthermore, morusin inhibited the TPA upregulation of cyclooxygenase 2 (COX-2), which may be regulated by AP-1 and NF-κB. In addition, noncytotoxic concentrations of morusin reduced the TPA-promoted cell growth of JB6 P + cells and inhibited TPA-induced malignant properties, such as cytoskeletal rearrangement and cell migration of JB6 P + cells. Similar to the effects of glutathione (GSH) pretreatment, morusin inhibited TPA-induced expression of N-cadeherin and vimentin, which are malignant cell surface proteins. Finally, morusin treatment dose-dependently suppressed the TPA-induced anchorage-independent cell transformation of JB6 P + cells. In conclusion, our results evidence that morusin possesses anti-cancer promotion potential because of its antioxidant property, which mediates multiple transformation-associated gene expression. Copyright © 2017 Elsevier B.V. All rights reserved.

Room-temperature cavity quantum electrodynamics with strongly coupled Dicke states

NASA Astrophysics Data System (ADS)

Breeze, Jonathan D.; Salvadori, Enrico; Sathian, Juna; Alford, Neil McN.; Kay, Christopher W. M.

2017-09-01

The strong coupling regime is essential for efficient transfer of excitations between states in different quantum systems on timescales shorter than their lifetimes. The coupling of single spins to microwave photons is very weak but can be enhanced by increasing the local density of states by reducing the magnetic mode volume of the cavity. In practice, it is difficult to achieve both small cavity mode volume and low cavity decay rate, so superconducting metals are often employed at cryogenic temperatures. For an ensembles of N spins, the spin-photon coupling can be enhanced by √{N } through collective spin excitations known as Dicke states. For sufficiently large N the collective spin-photon coupling can exceed both the spin decoherence and cavity decay rates, making the strong-coupling regime accessible. Here we demonstrate strong coupling and cavity quantum electrodynamics in a solid-state system at room-temperature. We generate an inverted spin-ensemble with N 1015 by photo-exciting pentacene molecules into spin-triplet states with spin dephasing time T2* 3 μs. When coupled to a 1.45 GHz TE01δ mode supported by a high Purcell factor strontium titanate dielectric cavity (Vm 0.25 cm3, Q 8,500), we observe Rabi oscillations in the microwave emission from collective Dicke states and a 1.8 MHz normal-mode splitting of the resultant collective spin-photon polariton. We also observe a cavity protection effect at the onset of the strong-coupling regime which decreases the polariton decay rate as the collective coupling increases.

In the Style of Henry Moore

ERIC Educational Resources Information Center

Hinshaw, Craig

2010-01-01

In this article, the author describes an art project inspired by Henry Moore's sculptures. This project consists of two activities. In the first activity, students select, sand and stain a wood block that would become a base for their plaster sculpture. This activity would keep the students independently engaged (classroom management) while the…

Henry Ward Beecher: A Nation's Tribune.

ERIC Educational Resources Information Center

Chandler, Daniel Ross

Henry Ward Beecher was America's most prominent 19th century liberal preacher and a major spokesperson for New England Transcendentalism. His philosophy integrated four fundamental themes: the creation of a moral code based on the internalization of values and peer group pressures, the establishment of the reform ideal of the impartial nonpartisan…

Transcendentalism and Henry Barnard's "School Architecture"

ERIC Educational Resources Information Center

Rothfork, John

1977-01-01

Sketches the intellectual and sociological climate that led Henry Barnard to advocate Greek Revival architecture for school buildings, takes a look at why this style and its implicit values were popular in the era between 1820-1860, and examines a few of the plans in Barnard's "School Architecture" (1838-48). (Author/RK)

Henri Matisse's "Beasts of the Sea"

ERIC Educational Resources Information Center

Graff, Robert

2010-01-01

Henri Matisse (1869-1954) was a very prolific Impressionist/Post-Impressionist artist whose longevity allowed him to produce many wonderful, brightly colored pieces of art that spanned different styles, movements and media. Elementary-school children love color and appreciate any project that does not require their work to be exact or totally…

Explaining fast radio bursts through Dicke's superradiance

NASA Astrophysics Data System (ADS)

Houde, Martin; Mathews, Abhilash; Rajabi, Fereshteh

2018-03-01

Fast radio bursts (FRBs), characterized by strong bursts of radiation intensity at radio wavelengths lasting on the order of a millisecond, have yet to be firmly associated with a family, or families, of astronomical sources. It follows that despite the large number of proposed models, no well-defined physical process has been identified to explain this phenomenon. In this paper, we demonstrate how Dicke's superradiance, for which evidence has recently been found in the interstellar medium, can account for the characteristics associated with FRBs. Our analysis and modelling of previously detected FRBs suggest they could originate from regions in many ways similar to those known to harbour masers or megamasers, and result from the coherent radiation emanating from populations of molecules associated with large-scale entangled quantum mechanical states. We estimate this entanglement to involve as many as ˜1030 to ˜1032 molecules over distances spanning 100-1000 au.

Cosmological constraints on Brans-Dicke theory.

PubMed

Avilez, A; Skordis, C

2014-07-04

We report strong cosmological constraints on the Brans-Dicke (BD) theory of gravity using cosmic microwave background data from Planck. We consider two types of models. First, the initial condition of the scalar field is fixed to give the same effective gravitational strength Geff today as the one measured on Earth, GN. In this case, the BD parameter ω is constrained to ω>692 at the 99% confidence level, an order of magnitude improvement over previous constraints. In the second type, the initial condition for the scalar is a free parameter leading to a somewhat stronger constraint of ω>890, while Geff is constrained to 0.981

Robert Dicke and the naissance of experimental gravity physics, 1957-1967

NASA Astrophysics Data System (ADS)

Peebles, Phillip James Edwin

2017-06-01

The experimental study of gravity became much more active in the late 1950s, a change pronounced enough be termed the birth, or naissance, of experimental gravity physics. I present a review of developments in this subject since 1915, through the broad range of new approaches that commenced in the late 1950s, and up to the transition of experimental gravity physics to what might be termed a normal and accepted part of physical science in the late 1960s. This review shows the importance of advances in technology, here as in all branches of natural science. The role of contingency is illustrated by Robert Dicke's decision in the mid-1950s to change directions in mid-career, to lead a research group dedicated to the experimental study of gravity. The review also shows the power of nonempirical evidence. Some in the 1950s felt that general relativity theory is so logically sound as to be scarcely worth the testing. But Dicke and others argued that a poorly tested theory is only that, and that other nonempirical arguments, based on Mach's Principle and Dirac's Large Numbers hypothesis, suggested it would be worth looking for a better theory of gravity. I conclude by offering lessons from this history, some peculiar to the study of gravity physics during the naissance, some of more general relevance. The central lesson, which is familiar but not always well advertised, is that physical theories can be empirically established, sometimes with surprising results.

Spin-squeezing and Dicke-state preparation by heterodyne measurement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vanderbruggen, T.; Bernon, S.; Bertoldi, A.

2011-01-15

We investigate the quantum nondemolition (QND) measurement of an atomic population based on a heterodyne detection and show that the induced back-action allows for the preparation of both spin-squeezed and Dicke states. We use a wave-vector formalism to describe the stochastic process of the measurement and the associated atomic evolution. Analytical formulas of the atomic distribution momenta are derived in the weak-coupling regime both for short- and long-time behavior, and they are in good agreement with those obtained by a Monte Carlo simulation. The experimental implementation of the proposed heterodyne detection scheme is discussed. The role played in the squeezingmore » process by the spontaneous emission is considered.« less

On the Henry constant and isosteric heat at zero loading in gas phase adsorption.

PubMed

Do, D D; Nicholson, D; Do, H D

2008-08-01

The Henry constant and the isosteric heat of adsorption at zero loading are commonly used as indicators of the strength of the affinity of an adsorbate for a solid adsorbent. It is assumed that (i) they are observable in practice, (ii) the Van Hoff's plot of the logarithm of the Henry constant versus the inverse of temperature is always linear and the slope is equal to the heat of adsorption, and (iii) the isosteric heat of adsorption at zero loading is either constant or weakly dependent on temperature. We show in this paper that none of these three points is necessarily correct, first because these variables might not be observable since they are outside the range of measurability; second that the linearity of the Van Hoff plot breaks down at very high temperature, and third that the isosteric heat versus loading is a strong function of temperature. We demonstrate these points using Monte Carlo integration and Monte Carlo simulation of adsorption of various gases on a graphite surface. Another issue concerning the Henry constant is related to the way the adsorption excess is defined. The most commonly used equation is the one that assumes that the void volume is the volume extended all the way to a boundary passing through the centres of the outermost solid atoms. With this definition the Henry constant can become negative at high temperatures. Although adsorption at these temperatures may not be practical because of the very low value of the Henry constant, it is more useful to define the Henry constant in such a way that it is always positive at all temperatures. Here we propose the use of the accessible volume; the volume probed by the adsorbate when it is in nonpositive regions of the potential, to calculate the Henry constant.

Antoine-Henri Jomini: A Bibliographical Survey.

ERIC Educational Resources Information Center

Alger, John I.

Although the writings of Antoine-Henri Jomini influenced military thought during the 19th and 20th centuries, the obscurity of their publishing history has led to misunderstandings of the development and substance of Jomini's thought. This review attempts to (1) point out the continuity of his thought on the conduct of war, and (2) provide an…

Henry Morgenthau's voice in history.

PubMed

Steiner, Pamela

2015-01-01

Henry Morgenthau (1856-1946) distinguished himself as the U.S. Ambassador to the Ottoman Empire, 1913-1916, and as the chairman of the League of Nations Refugee Settlement Commission (RSC) for Greece, 1923-24. I describe aspects of his early life that shaped the man he became, his accomplishments in these two posts, and his feelings about himself over time. At the end I briefly describe his attitude toward a possible Jewish state in Palestine.

Isotropic LQC and LQC-inspired models with a massless scalar field as generalised Brans-Dicke theories

NASA Astrophysics Data System (ADS)

Rama, S. Kalyana

2018-06-01

We explore whether generalised Brans-Dicke theories, which have a scalar field Φ and a function ω (Φ ), can be the effective actions leading to the effective equations of motion of the LQC and the LQC-inspired models, which have a massless scalar field σ and a function f( m). We find that this is possible for isotropic cosmology. We relate the pairs (σ , f) and (Φ , ω ) and, using examples, illustrate these relations. We find that near the bounce of the LQC evolutions for which f(m) = sin m, the corresponding field Φ → 0 and the function ω (Φ ) ∝ Φ ^2. We also find that the class of generalised Brans-Dicke theories, which we had found earlier to lead to non singular isotropic evolutions, may be written as an LQC-inspired model. The relations found here in the isotropic cases do not apply to the anisotropic cases, which perhaps require more general effective actions.

Keldysh approach for nonequilibrium phase transitions in quantum optics: Beyond the Dicke model in optical cavities

NASA Astrophysics Data System (ADS)

Torre, Emanuele G. Dalla; Diehl, Sebastian; Lukin, Mikhail D.; Sachdev, Subir; Strack, Philipp

2013-02-01

We investigate nonequilibrium phase transitions for driven atomic ensembles interacting with a cavity mode and coupled to a Markovian dissipative bath. In the thermodynamic limit and at low frequencies, we show that the distribution function of the photonic mode is thermal, with an effective temperature set by the atom-photon interaction strength. This behavior characterizes the static and dynamic critical exponents of the associated superradiance transition. Motivated by these considerations, we develop a general Keldysh path-integral approach that allows us to study physically relevant nonlinearities beyond the idealized Dicke model. Using standard diagrammatic techniques, we take into account the leading-order corrections due to the finite number N of atoms. For finite N, the photon mode behaves as a damped classical nonlinear oscillator at finite temperature. For the atoms, we propose a Dicke action that can be solved for any N and correctly captures the atoms’ depolarization due to dissipative dephasing.

General integrable n-level, many-mode Janes-Cummings-Dicke models and classical r-matrices with spectral parameters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Skrypnyk, T., E-mail: taras.skrypnyk@unimib.it, E-mail: tskrypnyk@imath.kiev.ua

Using the technique of classical r-matrices and quantum Lax operators, we construct the most general form of the quantum integrable “n-level, many-mode” spin-boson Jaynes-Cummings-Dicke-type hamiltonians describing an interaction of a molecule of N n-level atoms with many modes of electromagnetic field and containing, in general, additional non-linear interaction terms. We explicitly obtain the corresponding quantum Lax operators and spin-boson analogs of the generalized Gaudin hamiltonians and prove their quantum commutativity. We investigate symmetries of the obtained models that are associated with the geometric symmetries of the classical r-matrices and construct the corresponding algebra of quantum integrals. We consider in detailmore » three classes of non-skew-symmetric classical r-matrices with spectral parameters and explicitly obtain the corresponding quantum Lax operators and Jaynes-Cummings-Dicke-type hamiltonians depending on the considered r-matrix.« less

Three-dimensional pin-to-pin analyses of VVER-440 cores by the MOBY-DICK code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lehmann, M.; Mikolas, P.

1994-12-31

Nuclear design for the Dukovany (EDU) VVER-440s nuclear power plant is routinely performed by the MOBY-DICK system. After its implementation on Hewlett Packard series 700 workstations, it is able to perform routinely three-dimensional pin-to-pin core analyses. For purposes of code validation, the benchmark prepared from EDU operational data was solved.

Orbiting naked singularities in large-ω Brans-Dicke gravity

NASA Astrophysics Data System (ADS)

Chauvineau, Bertrand

2017-11-01

Brans-Dicke gravity admits spherical solutions describing naked singularities rather than black holes. Depending on some parameters entering such a solution, stable circular orbits exist for all radii. One shows that, despite the fact a naked singularity is an infinite redshift location, the far observed orbital motion frequency is unbounded for an adiabatically decreasing radius. We then argue that this feature remains true in a wide set of scalar(s)-tensor theories if gravity. This is a salient difference with general relativity, and the repercussion on the gravitational radiation by EMRI systems is stressed. Since this behaviour survives the ω \\longrightarrow ∞ limit, the possibility of such solutions is of utmost interest in the new gravitational wave astronomy context, despite the current constraints on scalar-tensor gravity.

Formation of multi-stereogenic centers using a catalytic diastereoselective Henry reaction.

PubMed

Arai, Takayoshi; Taneda, Yoshinori; Endo, Yoko

2010-11-14

A diastereoselective Henry reaction of chiral aldehydes with nitroalkanes was developed using a chiral sulfonyldiamine (L1)-CuCl complex. The reaction of (R)-2-phenylpropanal and nitromethane was smoothly catalyzed by the (S,S,S)-L1-CuCl complex to give the adduct with 99/1 syn/anti selectivity in 99% ee. In the reaction of (S)-2-phenylpropanal and nitroethane, the (R,R,R)-L1-CuCl catalyst yielded the expected three contiguous stereogenic centers in a highly syn-selective Henry reaction.

The Teaching Approach of Henry Schaefer-Simmern.

ERIC Educational Resources Information Center

Abrahamson, Roy E.

1980-01-01

This description of the teaching approach of Henry Schaefer-Simmern emphasizes his use of questioning to evoke student self-evaluation and to develop clarity of vision and interfunctional unity in students' art products and their mental, artistic conceiving. Two case reports of his work with elementary students are included. (Author/SJL)

Henry James on the Art of Acting.

ERIC Educational Resources Information Center

Thompson, David W.

Henry James, the nineteenth-century American novelist, also served on occasion as a theatre critic. Between 1875 and 1890 he reviewed several productions in Boston, New York, London, and Paris for "Atlantic Monthly" and other periodicals. The reviews are of interest because of James' high standards regarding acting and his often…

Robert Henry Thurston: Professionalism and Engineering Education

ERIC Educational Resources Information Center

Nienkamp, Paul

2016-01-01

Robert Henry Thurston is presented in this article. He provides one the most significant examples of professionalizing engineering through innovative education and promoting scientific education practices in the late nineteenth century. The son of a draftsmen and steam engine mechanic, Thurston spent his early years in Providence, Rhode Island.…

Effectiveness of an implementation optimisation intervention aimed at increasing parent engagement in HENRY, a childhood obesity prevention programme - the Optimising Family Engagement in HENRY (OFTEN) trial: study protocol for a randomised controlled trial.

PubMed

Bryant, Maria; Burton, Wendy; Cundill, Bonnie; Farrin, Amanda J; Nixon, Jane; Stevens, June; Roberts, Kim; Foy, Robbie; Rutter, Harry; Hartley, Suzanne; Tubeuf, Sandy; Collinson, Michelle; Brown, Julia

2017-01-24

Family-based interventions to prevent childhood obesity depend upon parents' taking action to improve diet and other lifestyle behaviours in their families. Programmes that attract and retain high numbers of parents provide an enhanced opportunity to improve public health and are also likely to be more cost-effective than those that do not. We have developed a theory-informed optimisation intervention to promote parent engagement within an existing childhood obesity prevention group programme, HENRY (Health Exercise Nutrition for the Really Young). Here, we describe a proposal to evaluate the effectiveness of this optimisation intervention in regard to the engagement of parents and cost-effectiveness. The Optimising Family Engagement in HENRY (OFTEN) trial is a cluster randomised controlled trial being conducted across 24 local authorities (approximately 144 children's centres) which currently deliver HENRY programmes. The primary outcome will be parental enrolment and attendance at the HENRY programme, assessed using routinely collected process data. Cost-effectiveness will be presented in terms of primary outcomes using acceptability curves and through eliciting the willingness to pay for the optimisation from HENRY commissioners. Secondary outcomes include the longitudinal impact of the optimisation, parent-reported infant intake of fruits and vegetables (as a proxy to compliance) and other parent-reported family habits and lifestyle. This innovative trial will provide evidence on the implementation of a theory-informed optimisation intervention to promote parent engagement in HENRY, a community-based childhood obesity prevention programme. The findings will be generalisable to other interventions delivered to parents in other community-based environments. This research meets the expressed needs of commissioners, children's centres and parents to optimise the potential impact that HENRY has on obesity prevention. A subsequent cluster randomised controlled pilot

Experimental observation of four-photon entangled Dicke state with high fidelity.

PubMed

Kiesel, N; Schmid, C; Tóth, G; Solano, E; Weinfurter, H

2007-02-09

We present the experimental observation of the symmetric four-photon entangled Dicke state with two excitations |D_{4};{(2)}. A simple experimental setup allowed quantum state tomography yielding a fidelity as high as 0.844+/-0.008. We study the entanglement persistency of the state using novel witness operators and focus on the demonstration of a remarkable property: depending on the orientation of a measurement on one photon, the remaining three photons are projected into both inequivalent classes of genuine tripartite entanglement, the Greenberger-Horne-Zeilinger and W class. Furthermore, we discuss possible applications of |D_{4};{(2)} in quantum communication.

1787 and 1776: Patrick Henry, James Madison, and the Revolutionary Legitimacy of the Constitution.

ERIC Educational Resources Information Center

Banning, Lance

1988-01-01

Discusses Patrick Henry's and James Madison's opinions on how the U.S. Constitution should be constructed. Describes how Henry introduced a set of substantive objections which were shared by Antifederalists throughout the country and persuaded many Revolutionaries that the Constitution was essentially at odds with the principles of 1776. (BSR)

The Ideas of Henry Jenkins and Libraries

ERIC Educational Resources Information Center

Anderson, Byron

2008-01-01

Henry Jenkins, director of the Comparative Media Studies Program at the Massachusetts Institute of Technology and keynote speaker at the 2007 American Library Association's "Gaming, Learning and Libraries Symposium" in Chicago is a visionary leader in the areas of new media and media convergence. In a white paper on digital media and learning…

Control-Structure Ratings on the Fox River at McHenry and Algonquin, Illinois

USGS Publications Warehouse

Straub, Timothy D.; Johnson, Gary P.; Hortness, Jon E.; Parker, Joseph R.

2009-01-01

The Illinois Department of Natural Resources-Office of Water Resources operates control structures on a reach of the Fox River in northeastern Illinois between McHenry and Algonquin. The structures maintain water levels in the river for flood-control and recreational purposes. This report documents flow ratings for hinged-crest gates, a broad-crested weir, sluice gates, and an ogee spillway on the control structures at McHenry and Algonquin. The ratings were determined by measuring headwater and tailwater stage along with streamflow at a wide range of flows at different gate openings. Standard control-structure rating techniques were used to rate each control structure. The control structures at McHenry consist of a 221-feet(ft)-long broad-crested weir, a 4-ft-wide fish ladder, a 50-ft-wide hinged-crest gate, five 13.75-ft-wide sluice gates, and a navigational lock. Sixty measurements were used to rate the McHenry structures. The control structures at Algonquin consist of a 242-ft-long ogee spillway and a 50-ft-wide hinged-crest gate. Forty-one measurements were used to rate the Algonquin control structures.

Production and Its Anti-hyperglycemic Effects of γ-Aminobutyric Acid from the Wild Yeast Strain Pichia silvicola UL6-1 and Sporobolomyces carnicolor 402-JB-1.

PubMed

Han, Sang-Min; Lee, Jong-Soo

2017-09-01

This study was done to produce γ-aminobutyric acid (GABA) from wild yeast as well as investigate its anti-hyperglycemic effects. Among ten GABA-producing yeast strains, Pichia silvicola UL6-1 and Sporobolomyces carnicolor 402-JB-1 produced high GABA concentration of 134.4 µg/mL and 179.2 µg/mL, respectively. P. silvicola UL6-1 showed a maximum GABA yield of 136.5 µg/mL and 200.8 µg/mL from S. carnicolor 402-JB-1 when they were cultured for 30 hr at 30℃ in yeast extract-peptone-dextrose medium. The cell-free extract from P. silvicola UL6-1 and S. carnicolor 402-JB-1 showed very high anti-hyperglycemic α-glucosidase inhibitory activity of 72.3% and 69.9%, respectively. Additionally, their cell-free extract-containing GABA showed the anti-hyperglycemic effect in streptozotocin-induced diabetic Sprague-Dawley rats.

Dissolved-Solids Load in Henrys Fork Upstream from the Confluence with Antelope Wash, Wyoming, Water Years 1970-2009

USGS Publications Warehouse

Foster, Katharine; Kenney, Terry A.

2010-01-01

Annual dissolved-solids load at the mouth of Henrys Fork was estimated by using data from U.S. Geological Survey streamflow-gaging station 09229500, Henrys Fork near Manila, Utah. The annual dissolved-solids load for water years 1970-2009 ranged from 18,300 tons in 1977 to 123,300 tons in 1983. Annual streamflows for this period ranged from 14,100 acre-feet in 1977 to 197,500 acre-feet in 1983. The 25-percent trimmed mean dissolved-solids load for water years 1970-2009 was 44,300 tons per year at Henrys Fork near Manila, Utah. Previous simulations using a SPAtially Referenced Regression On Watershed attributes (SPARROW) model for dissolved solids specific to water year 1991 conditions in the Upper Colorado River Basin predicted an annual dissolved-solids load of 25,000 tons for the Henrys Fork Basin upstream from Antelope Wash. On the basis of computed dissolved-solids load data from Henrys Fork near Manila, Utah, together with estimated annual dissolved-solids load from Antelope Wash and Peoples Canal, this prediction was adjusted to 37,200 tons. As determined by simulations with the Upper Colorado River Basin SPARROW model, approximately 56 percent (14,000 tons per year) of the dissolved-solids load at Henrys Fork upstream from Antelope Wash is associated with the 21,500 acres of irrigated agricultural lands in the upper Henrys Fork Basin.

NASA Remembers Gemini, Apollo Astronaut Dick Gordon

NASA Image and Video Library

2017-11-07

Astronaut Dick Gordon, command module pilot on Apollo 12, the second lunar landing mission, died on Monday, November 6 at the age of 88. A native of Seattle, Washington and 1951 graduate of the University of Washington, Gordon became an astronaut in 1963 after a career as a naval aviator. He spent more than 316 hours in space on two missions. He was the pilot for the three-day Gemini 11 mission in 1966 and performed two spacewalks. At the time of the flight, Gemini 11 set the world altitude record of 850 miles. Gordon made a second flight in 1969 as command pilot on Apollo 12 with spacecraft commander, Pete Conrad and lunar module pilot, Alan Bean. Throughout the 31-hour lunar surface stay by Conrad and Bean, Gordon remained in orbit around the moon on the command module, "Yankee Clipper." In November 2005, NASA honored Gordon with an Ambassador of Exploration award. NASA presented these prestigious awards to the astronauts who took part in the nation's Mercury, Gemini and Apollo space programs from 1961 to 1972.

Evaluating Henry's law constant of N-nitrosodimethylamine (NDMA).

PubMed

Haruta, Shinsuke; Jiao, Wentao; Chen, Weiping; Chang, Andrew C; Gan, Jay

2011-01-01

N-Nitrosodimethylamine (NDMA), a potential carcinogen, may contaminate the groundwater when the reclaimed wastewater is used for irrigation and groundwater recharge. Henry's law constant is a critical parameter to assess the fate and transport of reclaimed wastewater-borne NDMA in the soil profile. We conducted a laboratory experiment in which the change of NDMA concentration in water exposed to the atmosphere was measured with respect to time and, based on the data, obtained the dimensionless Henry's law constant (K(H)') of NDMA, at 1.0 x 10(-4). The K(H)' suggests that NDMA has a relatively high potential to volatilize in the field where NDMA-containing wastewater is used for irrigation and the volatilization loss may be a significant pathway of NDMA transport. The experiment was based on the two boundary-layer approach of mass transfer at the atmosphere-water interface. It is an expedient method to delineate K(H)' for volatile or semi-volatile compounds present in water at low concentrations.

Production and Its Anti-hyperglycemic Effects of γ-Aminobutyric Acid from the Wild Yeast Strain Pichia silvicola UL6-1 and Sporobolomyces carnicolor 402-JB-1

PubMed Central

Han, Sang-Min

2017-01-01

This study was done to produce γ-aminobutyric acid (GABA) from wild yeast as well as investigate its anti-hyperglycemic effects. Among ten GABA-producing yeast strains, Pichia silvicola UL6-1 and Sporobolomyces carnicolor 402-JB-1 produced high GABA concentration of 134.4 µg/mL and 179.2 µg/mL, respectively. P. silvicola UL6-1 showed a maximum GABA yield of 136.5 µg/mL and 200.8 µg/mL from S. carnicolor 402-JB-1 when they were cultured for 30 hr at 30℃ in yeast extract-peptone-dextrose medium. The cell-free extract from P. silvicola UL6-1 and S. carnicolor 402-JB-1 showed very high anti-hyperglycemic α-glucosidase inhibitory activity of 72.3% and 69.9%, respectively. Additionally, their cell-free extract-containing GABA showed the anti-hyperglycemic effect in streptozotocin-induced diabetic Sprague-Dawley rats. PMID:29138625

Obituary: Henry Albers (1925-2009)

NASA Astrophysics Data System (ADS)

Chromey, Fred

2011-12-01

Henry Albers, professor of astronomy at Vassar College for over thirty years, died March 29, 2009, in Fairhope, Alabama. For his work at Vassar, where he held the Maria Mitchell Chair, Albers received the first Maria Mitchell Women in Science Award for his inspiration of women astronomers. He said "In the final analysis it is the students who bring the joy into teaching." As a professional astronomer, Albers did observational work on Galactic structure in the southern Milky Way, and on the structure of the Magellanic Clouds. In retirement, Albers published Maria Mitchell - A Life in Journals and Letters, the firsthand account of America's first woman astronomer. Albers's research was on photographic near-infrared spectroscopy of red giant stars in the southern Milky Way, some proper motion studies, and on the structure of the Magellanic Clouds. A series of seven NSF grants supported his six trips to Chile to make spectroscopic observations, as well as his sabbatical collaborations at Minnesota, Leiden, and the Royal Observatory in Edinburgh. Henry Albers arrived at Vassar in 1958, to find an astronomy program that had been recently absorbed by the physics department, and that was suffering neglect after the retirement of Maud Makemson. For the next 31 years, with incredible energy -- he sometimes taught seven courses a year -- he built the astronomy program into one double in size (from one to two tenure lines), whose th century facilities have been replaced with a st century observatory. For a remarkable stretch of 20-some-years, Albers and physicist Bob Stearns, with considerable grace, alternated chairmanship of the joint department of physics and astronomy. Henry Albers was a devoted citizen of Vassar College and an enthusiastic participant in the process of faculty governance at that institution. He would have been the first to concede that his enthusiasm was sometimes excessive, and that his contributions at faculty meetings occasionally failed to move the

Variational treatment of entanglement in the Dicke model

NASA Astrophysics Data System (ADS)

Bakemeier, L.; Alvermann, A.; Fehske, H.

2015-10-01

We introduce a variational ansatz for the Dicke model that extends mean-field theory through the inclusion of spin-oscillator correlations. The correlated variational state is obtained from the mean-field product state via a unitary transformation. The ansatz becomes correct in the limit of large oscillator frequency and in the limit of a large spin, for which it captures the leading quantum corrections to the classical limit exactly including the spin-oscillator entanglement entropy. We explain the origin of the unitary transformation before we show that the ansatz improves substantially upon mean-field theory, giving near exact results for the ground state energy and very good results for other observables. We then discuss why the ansatz still encounters problems in the transition regime at moderate spin lengths, where it fails to capture the precursors of the superradiant quantum phase transition faithfully. This observation illustrates the principal limits of semi-classical formulations, even after they are extended with correlations and entanglement.

7. Historic American Buildings Survey. Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey. Photographed by Henry F. Withey September, 1936 NAVE TOWARD SANCTUARY. - Mission San Buenaventura, East Main Street & South Figueroa Street, Ventura, Ventura County, CA

1. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey Photographed by Henry F. Withey September, 1936 FRONT FACADE SOUTH. - Mission San Buenaventura, East Main Street & South Figueroa Street, Ventura, Ventura County, CA

6. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Historic American Buildings Survey Photographed by Henry F. Withey September, 1936 EAST ENTRANCE TO NAVE. - Mission San Buenaventura, East Main Street & South Figueroa Street, Ventura, Ventura County, CA

3. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey Photographed by Henry F. Withey December, 1936. SOUTH AND EAST FACADE. - Mission San Buenaventura, East Main Street & South Figueroa Street, Ventura, Ventura County, CA

5. Historic American Buildings Survey Photographed by Henry F. Withey, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Historic American Buildings Survey Photographed by Henry F. Withey, September, 1936 NORTH AND EAST FACADE. - Mission San Buenaventura, East Main Street & South Figueroa Street, Ventura, Ventura County, CA

Henry's Constants of Persistent Organic Pollutants by a Group-Contribution Method Based on Scaled-Particle Theory.

PubMed

Razdan, Neil K; Koshy, David M; Prausnitz, John M

2017-11-07

A group-contribution method based on scaled-particle theory was developed to predict Henry's constants for six families of persistent organic pollutants: polychlorinated benzenes, polychlorinated biphenyls, polychlorinated dibenzodioxins, polychlorinated dibenzofurans, polychlorinated naphthalenes, and polybrominated diphenyl ethers. The group-contribution model uses limited experimental data to obtain group-interaction parameters for an easy-to-use method to predict Henry's constants for systems where reliable experimental data are scarce. By using group-interaction parameters obtained from data reduction, scaled-particle theory gives the partial molar Gibbs energy of dissolution, Δg̅ 2 , allowing calculation of Henry's constant, H 2 , for more than 700 organic pollutants. The average deviation between predicted values of log H 2 and experiment is 4%. Application of an approximate van't Hoff equation gives the temperature dependence of Henry's constants for polychlorinated biphenyls, polychlorinated naphthalenes, and polybrominated diphenyl ethers in the environmentally relevant range 0-40 °C.

2. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Photographed by Henry F. Withey December, 1936 FRONT FACADE FROM SOUTH WEST. - Mission San Buenaventura, East Main Street & South Figueroa Street, Ventura, Ventura County, CA

4. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey Photographed by Henry F. Withey September 1936 SOUTH PORTION OF EAST FACADE. - Mission San Buenaventura, East Main Street & South Figueroa Street, Ventura, Ventura County, CA

The delusion of the Master: the last days of Henry James.

PubMed

Bartolomeo, Paolo

2013-11-01

The novelist Henry James shared with his brother William, the author of the Principles of Psychology, a deep interest in the ways in which personal identity is built through one's history and experiences. At the end of his life, Henry James suffered a vascular stroke in the right hemisphere and developed a striking identity delusion. He dictated in a perfectly clear and coherent manner two letters as if they were written by Napoleon Bonaparte. He also showed signs of reduplicative paramnesia. Negative symptoms resulting from right hemisphere damage may disrupt the feelings of "warmth and intimacy and immediacy" and the "resemblance among the parts of a continuum of feelings (especially bodily feelings)", which are the foundation of personal identity according to William James. On the other hand, a left hemisphere receiving inadequate input from the damaged right hemisphere may produce positive symptoms such as delusional, confabulatory narratives. Other fragments dictated during Henry James's final disease reveal some form of insight, if partial and disintegrated, into his condition. Thus, even when consciousness is impaired by brain damage, something of its deep nature may persist, as attested by the literary characteristics of the last fragments of the Master.

3. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey Photographed by Henry F. Withey December 1936 SOUTH ELEVATION - Jose Antonio Estudillo House, Mason Street & San Diego Avenue, Old Town, San Diego, San Diego County, CA

4. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey Photographed by Henry F. Withey December 1936 NORTH ELEVATION - Jose Antonio Estudillo House, Mason Street & San Diego Avenue, Old Town, San Diego, San Diego County, CA

Implications of Two Well-Known Models for Instructional Designers in Distance Education: Dick-Carey versus Morrison-Ross-Kemp

ERIC Educational Resources Information Center

Akbulut, Yavuz

2007-01-01

This paper first summarizes, and then compares and contrasts two well-known instructional design models: Dick and Carey Model (DC) and Morrison, Ross and Kemp model (MRK). The target audiences of both models are basically instructional designers. Both models have applications for different instructional design settings. They both see the…

A Teacher's Guide for William Shakespeare's "Henry V."

ERIC Educational Resources Information Center

WGBH-TV, Boston, MA.

This teacher's guide for William Shakespeare's play "Henry V" is designed to accompany the Kenneth Branagh Masterpiece Theater film production of the play, and to help teachers use the film in a variety of ways. The guide includes pre-viewing background information, five teaching units, and a pullout poster for classroom display. The…

A Re-examination of Henry Grady's New South.

ERIC Educational Resources Information Center

Mixon, Harold

Historian Henry Grady's speeches, particularly one delivered to the New England Club of New York City in 1886, are credited with persuading the North of the South's continued domination of blacks, its need for increased industrialization, and its broadened agriculture. Grady's term "The New South" is defined as a racially conservative,…

1. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey Photographed by Henry F. Withey June 1937 VIEW FROM NORTHWEST - Jose Antonio Estudillo House, Mason Street & San Diego Avenue, Old Town, San Diego, San Diego County, CA

2. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Photographed by Henry F. Withey June 1937 VIEW FROM SOUTHWEST - Jose Antonio Estudillo House, Mason Street & San Diego Avenue, Old Town, San Diego, San Diego County, CA

DETERMINATION OF HENRY'S LAW CONSTANTS OF SELECTED PRIORITY POLLUTANTS

EPA Science Inventory

The Henry's law constants (H) for 41 selected priority pollutants were determined to characterize these pollutants and provide information on their fate as they pass through wastewater treatment systems. All experimental values presented for H are averages of two or more replicat...

Mouse Strain Affects Behavioral and Neuroendocrine Stress Responses Following Administration of Probiotic Lactobacillus rhamnosus JB-1 or Traditional Antidepressant Fluoxetine.

PubMed

McVey Neufeld, Karen-Anne; Kay, Sebastian; Bienenstock, John

2018-01-01

Currently, there is keen interest in the development of alternative therapies in the treatment of depression. Given the explosion of research focused on the microbiota-gut-brain axis, consideration has turned to the potential of certain probiotics to improve patient outcomes for those suffering from mood disorders. Here we examine the abilities of a known antidepressant, fluoxetine, and the probiotic Lactobacillus rhamnosus JB-1™, to attenuate responses to two established criteria for depressive-like behavior in animal models, the tail suspension test (TST) and the corticosterone response to an acute restraint stressor. We examine two different strains of mice known to differ in the extent to which they express both anxiety-like behavior and measures of despair-BALB/c and Swiss Webster-with respectively high and normal behavioral phenotypes for each. While adult male BALB/c mice responded with increased antidepressive-like behavior to both fluoxetine and L. rhamnosus JB-1 in both the TST and the corticosterone stress response, SW mice did not respond to either treatment as compared to controls. These findings highlight the importance of investigating putative antidepressants in mouse strains known to express face validity for some markers of depression. Clinical studies examining the activity of L. rhamnosus JB-1 in patients suffering from mood disorders are warranted, as well as further pre-clinical work examining how interactions between host genotype and intestinal microbial alterations may impact behavioral responses. This study adds to the literature supporting the possibility that modifying the intestinal microbiota via probiotics represents a promising potential therapeutic breakthrough in the treatment of psychiatric disease.

Mouse Strain Affects Behavioral and Neuroendocrine Stress Responses Following Administration of Probiotic Lactobacillus rhamnosus JB-1 or Traditional Antidepressant Fluoxetine

PubMed Central

McVey Neufeld, Karen-Anne; Kay, Sebastian; Bienenstock, John

2018-01-01

Currently, there is keen interest in the development of alternative therapies in the treatment of depression. Given the explosion of research focused on the microbiota-gut-brain axis, consideration has turned to the potential of certain probiotics to improve patient outcomes for those suffering from mood disorders. Here we examine the abilities of a known antidepressant, fluoxetine, and the probiotic Lactobacillus rhamnosus JB-1™, to attenuate responses to two established criteria for depressive-like behavior in animal models, the tail suspension test (TST) and the corticosterone response to an acute restraint stressor. We examine two different strains of mice known to differ in the extent to which they express both anxiety-like behavior and measures of despair—BALB/c and Swiss Webster—with respectively high and normal behavioral phenotypes for each. While adult male BALB/c mice responded with increased antidepressive-like behavior to both fluoxetine and L. rhamnosus JB-1 in both the TST and the corticosterone stress response, SW mice did not respond to either treatment as compared to controls. These findings highlight the importance of investigating putative antidepressants in mouse strains known to express face validity for some markers of depression. Clinical studies examining the activity of L. rhamnosus JB-1 in patients suffering from mood disorders are warranted, as well as further pre-clinical work examining how interactions between host genotype and intestinal microbial alterations may impact behavioral responses. This study adds to the literature supporting the possibility that modifying the intestinal microbiota via probiotics represents a promising potential therapeutic breakthrough in the treatment of psychiatric disease.

A Derivation of the Dick Effect from Control-Loop Models for Periodically Interrogated Passive Frequency Standards

NASA Technical Reports Server (NTRS)

Greenhall, Charles A.

1996-01-01

The phase of a frequency standard that uses periodic interrogation and control of a local oscillator (LO) is degraded by a long-term random-walk component induced by downconversion of LO noise into the loop passband. The Dick formula for the noise level of this degradation can be derived from explicit solotions of two LO control-loop models. A summary of the derivations is given here.

5. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Historic American Buildings Survey Photographed by Henry F. Withey June 1937 DETAIL OF NORTH ELEVATION - Jose Antonio Estudillo House, Mason Street & San Diego Avenue, Old Town, San Diego, San Diego County, CA

9. Historic American Buildings Survey, Photographed by Henry F. Withey, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Historic American Buildings Survey, Photographed by Henry F. Withey, April 4th, 1934 SOUTH PORCH, LOOKING EAST - Mrs. A. L. M. Vhay House, 835 Leguna Street, Santa Barbara, Santa Barbara County, CA

Joseph Henry and Astronomy

NASA Astrophysics Data System (ADS)

Rothenberg, Marc

2016-01-01

Joseph Henry (1797-1878) is best known for his work in electromagnetism and as the first secretary of the Smithsonian Institution. But he was also a pioneer solar physicist, an early advocate of US participation in astrophysics, and a facilitator of international cooperation in astronomy. This paper will briefly trace his role in the development of the US astronomical community from the time he taught astronomy at Princeton in the 1830s through his death, focusing on failed efforts to persuade US astronomers and patrons of astronomy that the best path for US astronomy should be astrophysics. He thought that the US could make a more significant contribution to astronomy science by striking out on a less travelled path rather than competing with the established European observatories.

4. Historic American Buildings Survey, Henry Pleasants, History of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey, Henry Pleasants, History of the Old Eagle School, John C. Winston Co., 1909 PHOTOCOPY. - Eagle School, Old Eagle School Road (State Route 543) (Tredyffrin Township), Strafford, Chester County, PA

3. Historic American Buildings Survey, Henry Pleasants, History of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey, Henry Pleasants, History of the Old Eagle School, John C. Winston Co., 1909 PHOTOCOPY. - Eagle School, Old Eagle School Road (State Route 543) (Tredyffrin Township), Strafford, Chester County, PA

7. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey Photographed by Henry F. Withey December 1936 WINDOW DETAIL (EXTERIOR, SOUTH ELEVATION) - Jose Antonio Estudillo House, Mason Street & San Diego Avenue, Old Town, San Diego, San Diego County, CA

7. Historic American Buildings Survey, Photographed by Henry F. Withey, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey, Photographed by Henry F. Withey, April 4th, 1934. SOUTH PORCH FROM THE SOUTHWEST - Mrs. A. L. M. Vhay House, 835 Leguna Street, Santa Barbara, Santa Barbara County, CA

8. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Historic American Buildings Survey Photographed by Henry F. Withey April 4th, 1934 SOUTH PORCH AT SOUTHWEST CORNER - Mrs. A. L. M. Vhay House, 835 Leguna Street, Santa Barbara, Santa Barbara County, CA

2. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Photographed by Henry F. Withey April 4th, 1934 DETAIL OF FRONT FROM THE SOUTHWEST (NORTH?) - Yorbe-Abadie House, de la Guerra Plaza, Santa Barbara, Santa Barbara County, CA

Oxalate Content of the Herb Good-King-Henry, Blitum Bonus-Henricus

PubMed Central

Li, Wanying; Savage, Geoffrey P.

2015-01-01

The total, soluble and insoluble oxalate contents of the leaves, stems and buds of Good-King-Henry (Blitum Bonus-Henricus) were extracted and measured using HPLC chromatography. The large, mature leaves contained 42% more total oxalate than in the small leaves and the soluble oxalate content of the large leaves was 33% higher than the smaller leaves. Cooking the mixed leaves, stems and buds in boiling water for two minutes significantly (p < 0.05) reduced the total oxalate when compared to the raw plant parts. Pesto sauce made from mixed leaves contained 257 mg total oxalate/100 g fresh weight; this was largely made up of insoluble oxalates (85% of the total oxalate content). Soup made from mixed leaves contained lower levels of total oxalates (44.26 ± 0.49 mg total oxalate/100 g fresh weight) and insoluble oxalate made up 49% of the oxalate contents. The levels of oxalates in the Good-King-Henry leaves were high, suggesting that the leaves should be consumed occasionally as a delicacy because of their unique taste rather than as a significant part of the diet. However, the products made from Good-King-Henry leaves indicated that larger amounts could be consumed as the oxalate levels were reduced by dilution and processing. PMID:28231194

c-Jun/AP-1 pathway-mediated cyclin D1 expression participates in low dose arsenite-induced transformation in mouse epidermal JB6 Cl41 cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang Dongyun; Li Jingxia; Gao Jimin

2009-02-15

Arsenic is a well-documented human carcinogen associated with skin carcinogenesis. Our previous work reveals that arsenite exposure is able to induce cell transformation in mouse epidermal cell JB6 Cl41 through the activation of ERK, rather than JNK pathway. Our current studies further evaluate downstream pathway in low dose arsenite-induced cell transformation in JB6 Cl41 cells. Our results showed that treatment of cells with low dose arsenite induced activation of c-Jun/AP-1 pathway, and ectopic expression of dominant negative mutant of c-Jun (TAM67) blocked arsenite-induced transformation. Furthermore, our data indicated that cyclin D1 was an important downstream molecule involved in c-Jun/AP-1-mediated cellmore » transformation upon low dose arsenite exposure, because inhibition of cyclin D1 expression by its specific siRNA in the JB6 Cl41 cells resulted in impairment of anchorage-independent growth of cells induced by low dose arsenite. Collectively, our results demonstrate that c-Jun/AP-1-mediated cyclin D1 expression is at least one of the key events implicated in cell transformation upon low dose arsenite exposure.« less

Geology of the Henry Mountains

USGS Publications Warehouse

Gilbert, G.K.

1877-01-01

If these pages fail to give a correct account of the structure of the Henry Mountains the fault is mine and I have no excuse. In all the earlier exploration of the Rocky Mountain Region, as well as in much of the more recent survey, the geologist has merely accompanied the geographer and has had no voice in the determination of either the route or the rate of travel. When the structure of a mountain was in doubt he was rarely able to visit the points which should resolve the doubt, but was compelled to turn regretfully away. Not so in the survey of the Henry Mountains. Geological exploration had shown that they were well disposed for examination, and that they promised to give the key to a type of structure which was at best obscurely known; and I was sent by Professor Powell to make a study of them, without restriction as to my order or method. I was limited only in time, the snow stopping my work two months after it was begun. Two months would be far too short a period in which to survey a thousand square miles in Pennsylvania or Illinois, but among the Colorado Plateaus it proved sufficient. A few comprehensive views from mountain tops gave the general distribution of the formations, and the remainder of the time was spent in the examination of the localities which best displayed the peculiar features of the structure. So thorough was the display and so satisfactory the examination, that in preparing my report I have felt less than ever before the desire to revisit the field and prove my conclusions by more extended observation.

3. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey Photographed by Henry F. Withey April 1937. RUINS OF SMITHY (LOOKING S.W.) - Mission San Gabriel Arcangel, Industrial Shop (Ruins), West Mission Drive & Junipero Serra Street, San Gabriel, Los Angeles County, CA

9. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Historic American Buildings Survey Photographed by Henry F. Withey April 1937 RUINS OF TANNERY (FROM WEST CORNER) - Mission San Gabriel Arcangel, Industrial Shop (Ruins), West Mission Drive & Junipero Serra Street, San Gabriel, Los Angeles County, CA

6. Historic American Buildings Survey Photographed by Henry F. Withey, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Historic American Buildings Survey Photographed by Henry F. Withey, December 1936 DETAIL OF NORTH WING AND CORRIDOR (EAST END) - Jose Antonio Estudillo House, Mason Street & San Diego Avenue, Old Town, San Diego, San Diego County, CA

Enhancement of the thermoelectric figure of merit in DNA-like systems induced by Fano and Dicke effects.

PubMed

Fu, Hua-Hua; Gu, Lei; Wu, Dan-Dan; Zhang, Zu-Quan

2015-04-28

We report a theoretical study highlighting the thermoelectric properties of biological and synthetic DNA molecules. Based on an effective tight-binding model of duplex DNA and by using the nonequilibrium Green's function technique, the thermal conductance, electrical conductance, Seebeck coefficient and thermoelectric figure of merit in the system are numerically calculated by varying the asymmetries of energies and electronic hoppings in the backbone sites to simulate the environmental complications and fluctuations. We find that due to the multiple transport paths in the DNA molecule, the Fano antiresonance occurs, and enhances the Seebeck coefficient and the figure of merit. When the energy difference is produced in every opposite backbone site, the Dicke effect appears. This effect gives rise to a semiconducting-metallic transition, and enhances the thermoelectric efficiency of the DNA molecule remarkably. Moreover, as the Fano antiresonance point is close to the Dicke resonance one, a giant enhancement in the thermoelectric figure of merit in the DNA molecule has been found. These results provide a scenario to obtain effective routes to enhance the thermoelectric efficiency in the DNA molecules, and suggest perspectives for future experiments intending to control the thermoelectric transport in DNA-like nanodevices.

4. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey Photographed by Henry F. Withey April 1937 RUINS OF SMITHY FROM SO. WEST CORNER. - Mission San Gabriel Arcangel, Industrial Shop (Ruins), West Mission Drive & Junipero Serra Street, San Gabriel, Los Angeles County, CA

2. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Photographed by Henry F. Withey March 1936 VIEW OF FOUNTAIN IN MISSION PARK, MISSION PROPERTY AT ONE TIME. - Mission San Fernando Rey de Espana, Fountains, Mission Boulevard, San Fernando, Los Angeles County, CA

8. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Historic American Buildings Survey Photographed by Henry F. Withey April 1937 RUINS OF SOAP FACTORY FROM EAST CORNER. - Mission San Gabriel Arcangel, Industrial Shop (Ruins), West Mission Drive & Junipero Serra Street, San Gabriel, Los Angeles County, CA

7. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey Photographed by Henry F. Withey April 1937 RUINS OF SOAP FACTORY (S. W. Side) - Mission San Gabriel Arcangel, Industrial Shop (Ruins), West Mission Drive & Junipero Serra Street, San Gabriel, Los Angeles County, CA

2. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Photographed by Henry F. Withey December 1936 VIEW OF MISSION FROM SOUTH SIDE OF VALLEY (DISTANCE ABOUT 3 MILES) - Mission San Diego de Alcala, Misson Valley Road, San Diego, San Diego County, CA

The Transformative Intellectual: An Examination of Henry Giroux's Ethics

ERIC Educational Resources Information Center

Kashani, Tony

2012-01-01

This article explores Henry Giroux's contributions to critical pedagogy. The author demonstrates how Giroux, as a public intellectual, has found his Ethics in the right place. The author further argues that Giroux's Ethics of virtue are present not only in the public person but also in his transformative writing.

George Henry Hepting: Pioneer Leader in Forest Pathology

Treesearch

Ellis B. Cowling; Arthur Kelman; Harry R. Powers

1999-01-01

George Henry Hepting grew up in the city environment of Brooklyn, but early in his life developed a deep love and scientific interest in forestry. He became America's most skilled scientist in the theory and practice of forest pathology. He studied how long-lived forest trees, unlike most plants, cope with the long-term changes in their biological, physical, and...

Legitimate Techniques for Improving the R-Square and Related Statistics of a Multiple Regression Model

DTIC Science & Technology

1981-01-01

explanatory variable has been ommitted. Ramsey (1974) has developed a rather interesting test for detecting specification errors using estimates of the...Peter. (1979) A Guide to Econometrics , Cambridge, MA: The MIT Press. Ramsey , J.B. (1974), "Classical Model Selection Through Specification Error... Tests ," in P. Zarembka, Ed. Frontiers in Econometrics , New York: Academia Press. Theil, Henri. (1971), Principles of Econometrics , New York: John Wiley

5. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Historic American Buildings Survey Photographed by Henry F. Withey April 1937 RUINS OF SMITHY AND SOAP FACTORY (LOOKING SOUTH) - Mission San Gabriel Arcangel, Industrial Shop (Ruins), West Mission Drive & Junipero Serra Street, San Gabriel, Los Angeles County, CA

2. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Photographed by Henry F. Withey April 1937 RUINS OF FOUNTAIN, SMITHY AND SOAP FACTORY (LOOKING EAST) - Mission San Gabriel Arcangel, Industrial Shop (Ruins), West Mission Drive & Junipero Serra Street, San Gabriel, Los Angeles County, CA

7. Historic American Buildings Survey Photographed by Henry F. Withey, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey Photographed by Henry F. Withey, MaY 1937 SHOP RUINS (DETAIL OF SOAP OVEN) - Mission San Juan Capistrano, Industrial Shops, Olive Street, between U.S. Highway 101 & Main Street, San Juan Capistrano, Orange County, CA

22. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. Historic American Buildings Survey Photographed by Henry F. Withey June 1936 STONE CHURCH, ARCHES OF SANCTUARY AND WEST TRANSEPT - Mission San Juan Capistrano, Stone Church, Olive Street, between U.S. Highway 101 & Main Street, San Juan Capistrano, Orange County, CA

Final Environmental Assessment for Proposed Multi-Purpose Machine Gun Range at Joint Base McGuire-Dix-Lakehurst (JB MDL), New Jersey

DTIC Science & Technology

2015-09-01

Proposed MPMGR July 2015 JB MDL, New Jersey 2-2 Heating would be accomplished through electrical, geothermal , heat pump, or solar power. No fuel storage...emissions. Further, to the extent feasible, renewable energy (including, but not limited to solar, wind, geothermal 1 biogas, and biomass) and

6. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Historic American Buildings Survey Photographed by Henry F. Withey April 1937 RUINS OF SOAP FACTORY & SMITHY (FROM S. E. END OF SOAP FACTORY) - Mission San Gabriel Arcangel, Industrial Shop (Ruins), West Mission Drive & Junipero Serra Street, San Gabriel, Los Angeles County, CA

Henry's law constants of polyols

NASA Astrophysics Data System (ADS)

Compernolle, S.; Müller, J.-F.

2014-12-01

Henry's law constants (HLC) are derived for several polyols bearing between 2 and 6 hydroxyl groups, based on literature data for water activity, vapour pressure and/or solubility. While deriving HLC and depending on the case, also infinite dilution activity coefficients (IDACs), solid state vapour pressures or activity coefficient ratios are obtained as intermediate results. An error analysis on the intermediate quantities and the obtained HLC is included. For most compounds, these are the first values reported, while others compare favourably with literature data in most cases. Using these values and those from a previous work (Compernolle and Müller, 2014), an assessment is made on the partitioning of polyols, diacids and hydroxy acids to droplet and aqueous aerosol.

A path integral approach to the full Dicke model with dipole-dipole interaction

NASA Astrophysics Data System (ADS)

Aparicio Alcalde, M.; Stephany, J.; Svaiter, N. F.

2011-12-01

We consider the full Dicke spin-boson model composed by a single bosonic mode and an ensemble of N identical two-level atoms with different couplings for the resonant and anti-resonant interaction terms, and incorporate a dipole-dipole interaction between the atoms. Assuming that the system is in thermal equilibrium with a reservoir at temperature β-1, we compute the free energy in the thermodynamic limit N → ∞ in the saddle-point approximation to the path integral and determine the critical temperature for the super-radiant phase transition. In the zero temperature limit, we recover the critical coupling of the quantum phase transition, presented in the literature.

Intermediate accelerated solutions as generic late-time attractors in a modified Jordan-Brans-Dicke theory

NASA Astrophysics Data System (ADS)

Cid, Antonella; Leon, Genly; Leyva, Yoelsy

2016-02-01

In this paper we investigate the evolution of a Jordan-Brans-Dicke scalar field, Φ, with a power-law potential in the presence of a second scalar field, phi, with an exponential potential, in both the Jordan and the Einstein frames. We present the relation of our model with the induced gravity model with power-law potential and the integrability of this kind of models is discussed when the quintessence field phi is massless, and has a small velocity. The fact that for some fine-tuned values of the parameters we may get some integrable cosmological models, makes our choice of potentials very interesting. We prove that in Jordan-Brans-Dicke theory, the de Sitter solution is not a natural attractor. Instead, we show that the attractor in the Jordan frame corresponds to an ``intermediate accelerated'' solution of the form a(t) simeq eα1 tp1, as t → ∞ where α1 > 0 and 0 < p1 < 1, for a wide range of parameters. Furthermore, when we work in the Einstein frame we get that the attractor is also an ``intermediate accelerated'' solution of the form fraktur a(fraktur t) simeq eα2 fraktur tp2 as fraktur t → ∞ where α2 > 0 and 0

Challenging Texts: Teaching Deliberately--Reading Henry David Thoreau's "Walden"

ERIC Educational Resources Information Center

Davis, Andrea

2011-01-01

One of the more difficult 19th-century American texts for high school students to read is undoubtedly Henry David Thoreau's "Walden." His erudite allusions, often page-long sentences, and sophisticated sense of the ironic initially leave many students cold. Still, the author encourages them to read amid the din of a cultural cacophony that shouts…

Henry's law constants for dimethylsulfide in freshwater and seawater

NASA Technical Reports Server (NTRS)

Dacey, J. W. H.; Wakeham, S. G.; Howes, B. L.

1984-01-01

Distilled water and several waters of varying salinity were subjected, over a 0-32 C temperature range, to measurements for Henry's law constants for dimethylsulfide. Values for distilled water and seawater of the solubility parameters A and C are obtained which support the concept that the concentration of dimethylsulfide in the atmosphere is far from equilibrium with seawater.

The Failed Educations of John Stuart Mill and Henry Adams.

ERIC Educational Resources Information Center

Crossley, Robert

1979-01-01

Analyzes and contrasts Mill's "Autobiography" and Adams'"The Education of Henry Adams" in order to present two approaches to the nature of education and of failure. Maintains that their perspectives may serve as catalysts and cautions for contemporary theories of education and its utility and relevance. (CAM)

1. Historic American Buildings Survey Photographed by Henry F. Withey ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey Photographed by Henry F. Withey December 1936 VIEW OF MISSION VALLEY AND THE MISSION (LOOKING EAST FROM PRESIDIO HILL AT OLD TOWN, ORIGINAL SITE OF FIRST MISSION. - Mission San Diego de Alcala, Misson Valley Road, San Diego, San Diego County, CA

Intermediate accelerated solutions as generic late-time attractors in a modified Jordan-Brans-Dicke theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cid, Antonella; Leon, Genly; Leyva, Yoelsy, E-mail: acidm@ubiobio.cl, E-mail: genly.leon@ucv.cl, E-mail: yoelsy.leyva@uta.cl

2016-02-01

In this paper we investigate the evolution of a Jordan-Brans-Dicke scalar field, Φ, with a power-law potential in the presence of a second scalar field, φ, with an exponential potential, in both the Jordan and the Einstein frames. We present the relation of our model with the induced gravity model with power-law potential and the integrability of this kind of models is discussed when the quintessence field φ is massless, and has a small velocity. The fact that for some fine-tuned values of the parameters we may get some integrable cosmological models, makes our choice of potentials very interesting. Wemore » prove that in Jordan-Brans-Dicke theory, the de Sitter solution is not a natural attractor. Instead, we show that the attractor in the Jordan frame corresponds to an ''intermediate accelerated'' solution of the form a(t) ≅ e{sup α{sub 1} t{sup p{sup {sub 1}}}}, as t → ∞ where α{sub 1} > 0 and 0 < p{sub 1} < 1, for a wide range of parameters. Furthermore, when we work in the Einstein frame we get that the attractor is also an ''intermediate accelerated'' solution of the form a(t) ≅ e{sup α{sub 2} tp{sub 2}} as t → ∞ where α{sub 2} > 0 and 0« less

Spin squeezing as an indicator of quantum chaos in the Dicke model.

PubMed

Song, Lijun; Yan, Dong; Ma, Jian; Wang, Xiaoguang

2009-04-01

We study spin squeezing, an intrinsic quantum property, in the Dicke model without the rotating-wave approximation. We show that the spin squeezing can reveal the underlying chaotic and regular structures in phase space given by a Poincaré section, namely, it acts as an indicator of quantum chaos. Spin squeezing vanishes after a very short time for an initial coherent state centered in a chaotic region, whereas it persists over a longer time for the coherent state centered in a regular region of the phase space. We also study the distribution of the mean spin directions when quantum dynamics takes place. Finally, we discuss relations among spin squeezing, bosonic quadrature squeezing, and two-qubit entanglement in the dynamical processes.

Report on the geology of the Henry Mountains

USGS Publications Warehouse

Gilbert, G.K.

1877-01-01

The Henry Mountains have been visited only by the explorer. Previous to 1869 they were not placed upon any map, nor was mention made of them in any of the published accounts of exploration or survey in the Rocky Mountain region. In that year Professor Powell while descending the Colorado River in boats passed near their foot, and gave to them the name which they bear in honor of Prof. Joseph Henry, the distinguished physicist. In 1872 Prof. A. H. Thompson, engaged in the continuance of the survey of the river, led a party across the mountains by the Penellen Pass, and climbed some of the highest peaks. Frontiersmen in search of farming and grazing lands or of the precious metals have since that time paid several visits to the mountains; but no survey was made of them until the years 1875 and 1876, when Mr. Walter H. Graves and the writer visited them for that purpose. They are situated in Southern Utah, and are crossed by the meridian of 110° 45' and the thirty-eighth parallel. They stand upon the right bank of the Colorado River of the West, and between its tributaries, the Dirty Devil and the Escalante.

COASTAL CONDITIONS IN THE VIRGINIAN PROVINCE (CAPE COD TO CAPE HENRY)

EPA Science Inventory

The U.S. EPA Environmental Monitoring and Assessment Program (EMAP) collected ecological condition data during 1990 through 1993 from the estuarine waters of the Virginian Biogeographic Province (Cape Henry to Cape Cod) to answer broad-scale questions on environmental conditions...

Pryce-Hoyle Tensor in a Combined Einstein-Cartan-Brans-Dicke Model

NASA Astrophysics Data System (ADS)

Berman, Marcelo Samuel

2009-03-01

In addition to introducing matter injection through a scalar field determined by Pryce-Hoyle tensor, we also combine it with a BCDE (Brans-Dicke-Einstein-Cartan) theory with lambda-term developed earlier by Berman (Astrophys. Space Sci. 314:79-82, 2008), for inflationary scenario. It involves a variable cosmological constant, which decreases with time, jointly with energy density, cosmic pressure, shear, vorticity, and Hubble’s parameter, while the scale factor, total spin and scalar field increase exponentially. The post-inflationary fluid resembles a perfect one, though total spin grows, but not the angular speed (Berman, in Astrophys. Space Sci. 312:275, 2007). The Pryce-Hoyle tensor, which can measured by the number of injected particles per unit proper volume and time, as well as shear and vorticity, can be neglected in the aftermath of inflation (“no-hair”).

Fort McHenry National Monument and Historic Shrine. Teacher's Guide.

ERIC Educational Resources Information Center

Rogers, Jim

This teacher's guide explores Fort McHenry and the British attack on Baltimore Harbor (Maryland) in 1814. The guide contains 11 lessons: (1) "Where in the World Is Baltimore?" (no handout-use classroom resources); (2) "Why Baltimore?" (Handout-Why Baltimore?); (3) "Now Where Do We Place the Fort?" (Handout-Map of…

AdaMeasure: An Implementation of the Halstead and Henry Metrics.

DTIC Science & Technology

1987-06-01

of Departne t o Computer Science Kneale T..Nar4 ___. Dean of Information and Policy bScic:-n-- 2 Allr ABSTRACT I A software metric is a tool that...CONTENTS INTRODUCTION AND BACKGROUND ......................... 6 A. DEFINITIONS ..................................................... 6 B. SALLIE HENRY’S...METRIC.................................... 6 C. INFORMATION FLOW .......................................... 7 D. RELATIONS

Taxing junk food: applying the logic of the Henry tax review to food.

PubMed

Bond, Molly E; Williams, Michael J; Crammond, Brad; Loff, Bebe

2010-10-18

The recent review of taxation in Australia - the Henry tax review - has recommended that the federal government increase the taxes already levied on tobacco and alcohol. Tobacco and alcohol taxes are put forward as the best way of reducing the social harms caused by the use and misuse of these substances. Junk foods have the same pattern of misuse and the same social costs as tobacco and alcohol. The Henry tax review rejects the idea of taxing fatty foods, and to date the government has not implemented a tax on junk food. We propose that a tax on junk food be implemented as a tool to reduce consumption and address the obesity epidemic.

Cooperative emission of light by an ensemble of dipoles near a metal nanoparticle: the plasmonic Dicke effect.

PubMed

Pustovit, Vitaliy N; Shahbazyan, Tigran V

2009-02-20

We identify a new mechanism for cooperative emission of light by an ensemble of N dipoles near a metal nanostructure supporting a surface plasmon. The cross talk between emitters due to the virtual plasmon exchange leads to the formation of three plasmonic superradiant modes whose radiative decay rates scale with N, while the total radiated energy is thrice that of a single emitter. Our numerical simulations indicate that the plasmonic Dicke effect survives nonradiative losses in the metal.

[From apprenticeship to Nobel Prize: Henri Moissan's fabulous destiny].

PubMed

Lafont, O

2008-01-01

Born in Paris on September 28, 1852, son of an eastern railways' employee and of a dressmaker, Henri Moissan's secondary schooling in Meaux did not allow him to get access to the sesame diploma "baccalauréat" (GCE). In 1869, he did obtain a special certificate of secondary schooling so that he could become an apprentice in watch making. That could have been the end of the story, but dreadful event for France appeared to have beneficial effects for Moissan. Under the threat of the Prussian army, Moissan's family took refuge near Paris. This gave the young Henri the opportunity to register as a student for the second-class pharmacy diploma, which did not need, at the time, the GCE. Moissan became then a trainee in pharmacy in 1871. Meanwhile, he followed the special schooling of "Ecole de chimie" founded by E. Frémy, and then joined the laboratory of Dehérain at the Museum, where he worked in plant physiology. He finally obtained the famous "baccalauréat" (GCE) and could register as a student in first-class pharmacy. He became a pharmacist as well as a doctor in sciences. In 1883, Moissan was named professor at the school of pharmacy in Paris. In 1886, he isolated fluorine by electrolysis of fluorhydric acid, in the presence of potassium fluoride, at a low temperature. He then studied diamond synthesis and gave a start to high temperature chemistry, designing his famous furnace. These findings and many others allowed Moissan to rise to membership in many learned academies around the world. Crowning achievement, Moissan won the Nobel Prize in 1906. A man of culture, collector of autographs and paintings, he died in 1907. Nothing of that would have been possible if there had not been a second-class pharmacist diploma. The history of Henri Moissan is one of a rise from apprenticeship to the Nobel Prize.

Henry constant and isosteric heat at zero-loading for gas adsorption in carbon nanotubes.

PubMed

Do, D D; Do, H D; Wongkoblap, A; Nicholson, D

2008-12-28

The Henry constant and the isosteric heat of adsorption at zero loading in a carbon nanotube bundle are studied with Monte Carlo integration for the adsorption of gases over a range of temperatures. The spacing between nanotubes in a bundle is determined from the minimization of potential energy of interaction between these tubes. We study different tube configurations with bundles of 2, 3, 4 and 7 tubes. Depending on the configuration it is found that the spacing is of between 0.31 to 0.333 nm, and this falls within the range reported in the literature. The Henry constant has been carefully defined so that it will not become negative at high temperatures. This is done with the aid of accessible volume, rather than the usual absolute void volume. We show that linearity of the van't Hoff plot for the Henry constant is not strictly followed. Furthermore the slope of this plot is not equal to the isosteric heat of adsorption at zero loading, which is found to be a strong function of temperature. From the results we find that the Henry constant and the heat of adsorption depend on the tube configuration. In general the adsorption in the cusp interstices is strongest followed by that inside the tube and finally on the outer surface. However for very small tubes adsorption occurs inside the tube first. For molecules with orientation, the behaviour is even more interesting and the shape of the isosteric heat versus temperature depends on the degree of orientation, tube configuration and the domain of adsorption (interstices, inside the tube and on the outer surface).

HABS DC,WASH,515A (sheet 1 of 4) Captain Henry Saunders ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HABS DC,WASH,515A- (sheet 1 of 4) - Captain Henry Saunders House, Virginia Room, National Museum of American History, Smithsonian Institution (moved from VA, Windsor vicinity, U.S. Route 460), Washington, District of Columbia, DC

HABS DC,WASH,515A (sheet 4 of 4) Captain Henry Saunders ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HABS DC,WASH,515A- (sheet 4 of 4) - Captain Henry Saunders House, Virginia Room, National Museum of American History, Smithsonian Institution (moved from VA, Windsor vicinity, U.S. Route 460), Washington, District of Columbia, DC

HABS DC,WASH,515A (sheet 2 of 4) Captain Henry Saunders ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HABS DC,WASH,515A- (sheet 2 of 4) - Captain Henry Saunders House, Virginia Room, National Museum of American History, Smithsonian Institution (moved from VA, Windsor vicinity, U.S. Route 460), Washington, District of Columbia, DC

HABS DC,WASH,515A (sheet 3 of 4) Captain Henry Saunders ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HABS DC,WASH,515A- (sheet 3 of 4) - Captain Henry Saunders House, Virginia Room, National Museum of American History, Smithsonian Institution (moved from VA, Windsor vicinity, U.S. Route 460), Washington, District of Columbia, DC

The last ride of Henry II of France: orbital injury and a king's demise.

PubMed

Eftekhari, Kian; Choe, Christina H; Vagefi, M Reza; Eckstein, Lauren A

2015-01-01

Jousting was a popular pastime for royalty in the Renaissance era. Injuries were common, and the eye was particularly at risk from the splinters of the wooden lance. On June 30, 1559, Henry II of France participated in a jousting tournament to celebrate two royal weddings. In the third match, Gabriel de Montgomery struck Henry on the right shoulder and the lance splintered, sending wooden shards into his face and right orbit. Despite being cared for by the prominent physicians Ambroise Paré and Andreas Vesalius, the king died 10 days later and was found to have a cerebral abscess. The wound was not explored immediately after the injury; nevertheless, wooden foreign bodies were discovered in the orbit at the time of autopsy. The dura had not been violated, suggesting that an infection may have traveled from the orbit into the brain. Nostradamus and Luca Guarico, the astrologer to the Medici family, had prophesied the death of Henry II of France, but he ignored their warnings and thus changed the course of history in Renaissance Europe. Copyright © 2015 Elsevier Inc. All rights reserved.

Guy V. Henry: A Study in Military Leadership

DTIC Science & Technology

1985-05-13

supplies; and obtain recruits for his black regiments. In approving Gillmore’s plan, President Lincoln hoped to accomplish an even more ambitious objective...defenses of Jacksonville, Baldwin, and the South Fork of the St. Mary’s (Barber’s Ford). Gillmore considered it well understood that there would be no...September 9, 1891, Williams-Henry Papers. 47 q., 290R, XXV, pt I, p. 279. For overview of the Florida campaign see Shelby Foote, The Civil War, A Narrative

Determination of Henry`s law constants by equilibrium partitioning in a closed system using a new in situ optical absorbance method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allen, J.M.; Balcavage, W.X.; Ramachandran, B.R.

Currently, a great deal of interest exists in developing quantitative descriptions of the transport behavior for organic chemical compounds in the environment. Transport between water and air is of particular significance in this regard. A new method for measurement of thermodynamic Henry`s law constants (H) is reported. In this method, the optical absorbance of a dilute aqueous solution containing an organic compound is followed with time as the compound partitions into the air above the solution in a sealed vessel. The change in optical absorbance and the vapor to liquid volume ratio of the vessel are then used to calculatemore » the value for H. The concentration of the organic compound in the aqueous and vapor phases need not be known. This method allows the approach to equilibrium to be observed in real time so that attainment of equilibrium is readily apparent. This method works particularly well for water-soluble compounds having low vapor pressures. The applicability of this method is limited to compounds that exhibit significant optical absorbance in the ultraviolet and visible regions of the electromagnetic spectrum. Values for H and their temperature dependencies measured using this new method are reported for methacrolein, methyl vinyl ketone, benzaldehyde, and acetophenone. Values for H are also reported for benzene, toluene, and ethylbenzene at 298 K. All reported H data are compared with previously reported values.« less

Planning in Public Education: Lessons from Horace Mann and Henry Barnard

ERIC Educational Resources Information Center

Henkin, Alan B.; Ignasias, C. Dennis

1978-01-01

A handful of educational reformers from each generation effectively muster and sustain public support in efforts to advance their visions for education. Here is an account of the efforts of Horace Mann and Henry Barnard acting as educational advocates and consensus builders who evoked public responsiveness and guided their constituencies toward…

STS-4 post flight crew debriefing in JSC conference room

NASA Technical Reports Server (NTRS)

1982-01-01

STS-4 Commander Ken Mattingly and Pilot Henry Hartsfield discuss mission events with astronauts and administrators during a post flight crew debriefing held in a JSC conference room. Seated around the conference table clockwise (from lower left) are astronaut William B. Lenoir, Hartsfield, Mattingly, astronaut Robert F. Overmyer, astronaut S. David Griggs, astronaut Karol J. Bobko, astronaut John W. Young, administrator George W. Abbey, and astronaut Vance D. Brand. On the perimeter of the room are astronaut George D. Nelson (left) and astronaut Francis (Dick) Scobee (right).

Enter the Madcap Prince of Wales: Students Directing "Henry IV, Part I."

ERIC Educational Resources Information Center

Earthman, Elise Ann

1993-01-01

Argues that William Shakespeare's "Henry IV, Part I" is an appropriate and useful text for secondary English classrooms. Shows how the play lends itself to performance-based instruction. Outlines ways of accomplishing student engagement, using film versions, and assigning written work. (HB)

Mounting a Curricular Revolution: An Interview with Henry Louis Gates, Jr.

ERIC Educational Resources Information Center

von Zastrow, Claus

2009-01-01

This article presents an interview with Henry Louis Gates, Jr., Harvard professor and cultural critic who has captured 25 million viewers with his PBS documentary series, African American Lives (WNET). Using genealogical research and DNA science, Gates traces the family history of 19 famous African Americans. What results is a rich and moving…

Henry Evelyn Bliss--The Other Immortal, or a Prophet without Honour?

ERIC Educational Resources Information Center

Broughton, Vanda

2008-01-01

The paper takes a retrospective look at the work of Henry Evelyn Bliss, classificationist theorist and author of the "Bibliographic Classification". Major features of his writings and philosophy are examined and evaluated for the originality of their contribution to the corpus of knowledge in the discipline. Reactions to Bliss's work are analysed,…

Henry Barton Jacobs, William Osler's intimate friend

PubMed Central

2017-01-01

William Osler was considered a universal friend by physicians of his era but, as with most people, his intimate friends were few. Henry Barton Jacobs became a close friend as one of the “latchkeyers” who lived next door to the Oslers in Baltimore, and the friendship intensified after Jacobs married Mary Sloan Frick Garrett, the fabulously wealthy widow of a former patient. The couples stayed close after the Oslers moved to Oxford, vacationing together and corresponding frequently. The couple friendship between the Oslers and the Jacobses benefited American medicine in specific ways, including the care of patients with tuberculosis and the care of children. PMID:28127152

[Assassination of Henri IV, mental disorders and criminal responsibility].

PubMed

Bouchard, Jean-Pierre

2010-01-01

On 14th May 1610, François Ravaillac, a delusional mystic, assassinated King Henri IV. Under the Ancien Regime, regicide was considered as a supreme act of patricide and received the ultimate punishment even if the perpetrator showed obvious signs of insanity. What would the situation be today? A study of this notorious historical episode provides a reflection on the way dangerousness linked to mental disorders has been viewed and treated over the last four centuries.

Henry Carmichael [1796 to 1862]: Australia's Pioneer Adult Educator

ERIC Educational Resources Information Center

Morris, Roger K.

2016-01-01

This paper outlines the important role that Henry Carmichael played in the foundation of adult education in Australia. He was the driving force in the foundation and early success of the Sydney Mechanics' School of Arts. He also played a very significant role in the establishment of public schooling. His wide interest in educational thought is…

Movement, Memory and Mathematics: Henri Bergson and the Ontology of Learning

ERIC Educational Resources Information Center

de Freitas, Elizabeth; Ferrara, Francesca

2015-01-01

Using the work of philosopher Henri Bergson (1859-1941) to examine the nature of movement and memory, this article contributes to recent research on the role of the body in learning mathematics. Our aim in this paper is to introduce the ideas of Bergson and to show how these ideas shed light on mathematics classroom activity. Bergson's monist…

Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins

PubMed Central

Batra, Jyoti; Tripathi, Shashank; Kumar, Amrita; Katz, Jacqueline M.; Cox, Nancy J.; Lal, Renu B.; Sambhara, Suryaprakash; Lal, Sunil K.

2016-01-01

A unique feature of influenza A virus (IAV) life cycle is replication of the viral genome in the host cell nucleus. The nuclear import of IAV genome is an indispensable step in establishing virus infection. IAV nucleoprotein (NP) is known to mediate the nuclear import of viral genome via its nuclear localization signals. Here, we demonstrate that cellular heat shock protein 40 (Hsp40/DnaJB1) facilitates the nuclear import of incoming IAV viral ribonucleoproteins (vRNPs) and is important for efficient IAV replication. Hsp40 was found to interact with NP component of IAV RNPs during early stages of infection. This interaction is mediated by the J domain of Hsp40 and N-terminal region of NP. Drug or RNAi mediated inhibition of Hsp40 resulted in reduced nuclear import of IAV RNPs, diminished viral polymerase function and attenuates overall viral replication. Hsp40 was also found to be required for efficient association between NP and importin alpha, which is crucial for IAV RNP nuclear translocation. These studies demonstrate an important role for cellular chaperone Hsp40/DnaJB1 in influenza A virus life cycle by assisting nuclear trafficking of viral ribonucleoproteins. PMID:26750153

Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins.

PubMed

Batra, Jyoti; Tripathi, Shashank; Kumar, Amrita; Katz, Jacqueline M; Cox, Nancy J; Lal, Renu B; Sambhara, Suryaprakash; Lal, Sunil K

2016-01-11

A unique feature of influenza A virus (IAV) life cycle is replication of the viral genome in the host cell nucleus. The nuclear import of IAV genome is an indispensable step in establishing virus infection. IAV nucleoprotein (NP) is known to mediate the nuclear import of viral genome via its nuclear localization signals. Here, we demonstrate that cellular heat shock protein 40 (Hsp40/DnaJB1) facilitates the nuclear import of incoming IAV viral ribonucleoproteins (vRNPs) and is important for efficient IAV replication. Hsp40 was found to interact with NP component of IAV RNPs during early stages of infection. This interaction is mediated by the J domain of Hsp40 and N-terminal region of NP. Drug or RNAi mediated inhibition of Hsp40 resulted in reduced nuclear import of IAV RNPs, diminished viral polymerase function and attenuates overall viral replication. Hsp40 was also found to be required for efficient association between NP and importin alpha, which is crucial for IAV RNP nuclear translocation. These studies demonstrate an important role for cellular chaperone Hsp40/DnaJB1 in influenza A virus life cycle by assisting nuclear trafficking of viral ribonucleoproteins.

View of Crew Commander Henry Hartsfield Jr. loading film into IMAX camera

NASA Image and Video Library

1984-09-08

41D-11-004 (8 September 1984 --- View of Crew Commander Henry Hartsfield Jr. loading film into the IMAX camera during the 41-D mission. The camera is floating in front of the middeck lockers. Above it is a sticker of the University of Kansas mascott, the Jayhawk.

The Imaginary World of Henri Rousseau. Teacher's Guide. School Arts: Looking/Learning.

ERIC Educational Resources Information Center

Henderson, Anne

While Henri Rousseau's work was not easily classified into any definitive artistic style of the time--impressionism, post-impressionism, fauvism, or cubism--it has been considered a forerunner of surrealism because of its dreamlike sensibility. This teaching guide provides information about Rousseau and his work, focusing on "Tropical Forest…

Silibinin inhibits ultraviolet B radiation-induced DNA-damage and apoptosis by enhancing interleukin-12 expression in JB6 cells and SKH-1 hairless mouse skin.

PubMed

Narayanapillai, Sreekanth; Agarwal, Chapla; Deep, Gagan; Agarwal, Rajesh

2014-06-01

Recent studies have demonstrated silibinin efficacy against ultraviolet B (UVB)-induced skin carcinogenesis via different mechanisms in cell lines and animal models; however, its role in regulating interleukin-12 (IL-12), an immunomodulatory cytokine that reduces UVB-induced DNA damage and apoptosis, is not known. Here, we report that UVB irradiation causes caspase 3 and PARP cleavage and apoptosis, and addition of recombinant IL-12 or silibinin immediately after UVB significantly protects UVB-induced apoptosis in JB6 cells. IL-12 antibody-mediated blocking of IL-12 activity compromised the protective effects of both IL-12 and silibinin. Both silibinin and IL-12 also accelerated the repair of UVB-caused cyclobutane-pyrimidine dimers (CPDs) in JB6 cells. Additional studies confirmed that indeed silibinin causes a significant increase in IL-12 levels in UVB-irradiated JB6 cells as well as in mouse skin epidermis, and that similar to cell-culture findings, silibinin topical application immediately after UVB exposure causes a strong protection against UVB-induced TUNEL positive cells in epidermis possibly through a significantly accelerated repair of UVB-caused CPDs. Together, these findings for the first time provide an important insight regarding the pharmacological mechanism wherein silibinin induces endogenous IL-12 in its efficacy against UVB-caused skin damages. In view of the fact that an enhanced endogenous IL-12 level could effectively remove UVB-caused DNA damage and associated skin cancer, our findings suggest that the use of silibinin in UVB-damaged human skin would also be a practical and translational strategy to manage solar radiation-caused skin damages as well as skin cancer. © 2013 Wiley Periodicals, Inc.

Volatility dependence of Henry's law constants of condensable organics: Application to estimate depositional loss of secondary organic aerosols

NASA Astrophysics Data System (ADS)

Hodzic, A.; Aumont, B.; Knote, C.; Lee-Taylor, J.; Madronich, S.; Tyndall, G.

2014-07-01

The water solubility of oxidation intermediates of volatile organic compounds that can condense to form secondary organic aerosol (SOA) is largely unconstrained in current chemistry-climate models. We apply the Generator of Explicit Chemistry and Kinetics of Organics in the Atmosphere to calculate Henry's law constants for these intermediate species. Results show a strong negative correlation between Henry's law constants and saturation vapor pressures. Details depend on precursor species, extent of photochemical processing, and NOx levels. Henry's law constants as a function of volatility are made available over a wide range of vapor pressures for use in 3-D models. In an application using the Weather Research and Forecasting model coupled with Chemistry (WRF-Chem) over the U.S. in summer, we find that dry (and wet) deposition of condensable organic vapors leads to major reductions in SOA, decreasing surface concentrations by ~50% (10%) for biogenic and ~40% (6%) for short chain anthropogenic precursors under the considered volatility conditions.

Investigation of Solvent Effects on the Rate and Stereoselectivity of the Henry Reaction

PubMed Central

Kostal, Jakub; Voutchkova, Adelina M.; Jorgensen, William L.

2011-01-01

A combined computational and experimental kinetic study on the Henry reaction is reported. The effects of salvation on the transition structures and the rates of reaction between nitromethane and formaldehyde, and between nitropropane and benzaldehyde are elucidated with QM/MM calculations. PMID:22168236

[Henri Ellenberger, Henri Ey and the Traité de Psychiatrie in the "Encyclopédie Médico-Chirurgicale": an American career under the auspices of the "Evolution Psychiatrique"].

PubMed

Delille, Emmanuel

2006-01-01

Henri Ellenberger, psychiatrist and historian, experienced a decisive period in his career in the early fifties of the last century. Educated in France, intern at Sainte-Anne Hospital, he was working in Switzerland after the war and then tried to move to the United States. It was during his participation in the French group "l'Evolution Psychiatrique" that he happened to contribute to the treatise of psychiatry (1955) of the French medical and surgical encyclopaedia ("EMC") and organise an observation trip to the United States. He was supported at that time by Henri Ey, key figure of French psychiatry. While going back to his career, we would like to emphasise on his comments about the "Psychotherapy of schizophrenia". Even though later Ellenberger became a well-known researcher in North America, it is more a question for us to discuss the scientific ambition he had in this particular context of a French learned society as a member of "l'Evolution Psychiatrique" and as a psychiatrist formerly intern from the "Hôpitaux psychiatriques de la Seine" (Parisian district).

On the emergence of the ΛCDM model from self-interacting Brans-Dicke theory in d= 5

NASA Astrophysics Data System (ADS)

Reyes, Luz Marina; Perez Bergliaffa, Santiago Esteban

2018-01-01

We investigate whether a self-interacting Brans-Dicke theory in d=5 without matter and with a time-dependent metric can describe, after dimensional reduction to d=4, the FLRW model with accelerated expansion and non-relativistic matter. By rewriting the effective 4-dimensional theory as an autonomous 3-dimensional dynamical system and studying its critical points, we show that the ΛCDM cosmology cannot emerge from such a model. This result suggests that a richer structure in d=5 may be needed to obtain the accelerated expansion as well as the matter content of the 4-dimensional universe.

Henry Mayhew: journalist, social investigator, and foreshadower of qualitative research.

PubMed

Nunes, Everardo Duarte

2012-09-01

As a journalist, Henry Mayhew recorded daily life in London in the latter half of the nineteenth century. His approach remains of interest to historians and social scientists today in that it foreshadowed qualitative research. The article highlights methodological aspects of Mayhew's investigations and analyzes two of his reports, one on a cholera outbreak and the other on a female street vendor. It also addresses some analyses that have critiqued his work.

Quantum signature of chaos and thermalization in the kicked Dicke model

NASA Astrophysics Data System (ADS)

Ray, S.; Ghosh, A.; Sinha, S.

2016-09-01

We study the quantum dynamics of the kicked Dicke model (KDM) in terms of the Floquet operator, and we analyze the connection between chaos and thermalization in this context. The Hamiltonian map is constructed by suitably taking the classical limit of the Heisenberg equation of motion to study the corresponding phase-space dynamics, which shows a crossover from regular to chaotic motion by tuning the kicking strength. The fixed-point analysis and calculation of the Lyapunov exponent (LE) provide us with a complete picture of the onset of chaos in phase-space dynamics. We carry out a spectral analysis of the Floquet operator, which includes a calculation of the quasienergy spacing distribution and structural entropy to show the correspondence to the random matrix theory in the chaotic regime. Finally, we analyze the thermodynamics and statistical properties of the bosonic sector as well as the spin sector, and we discuss how such a periodically kicked system relaxes to a thermalized state in accordance with the laws of statistical mechanics.

Quantum signature of chaos and thermalization in the kicked Dicke model.

PubMed

Ray, S; Ghosh, A; Sinha, S

2016-09-01

We study the quantum dynamics of the kicked Dicke model (KDM) in terms of the Floquet operator, and we analyze the connection between chaos and thermalization in this context. The Hamiltonian map is constructed by suitably taking the classical limit of the Heisenberg equation of motion to study the corresponding phase-space dynamics, which shows a crossover from regular to chaotic motion by tuning the kicking strength. The fixed-point analysis and calculation of the Lyapunov exponent (LE) provide us with a complete picture of the onset of chaos in phase-space dynamics. We carry out a spectral analysis of the Floquet operator, which includes a calculation of the quasienergy spacing distribution and structural entropy to show the correspondence to the random matrix theory in the chaotic regime. Finally, we analyze the thermodynamics and statistical properties of the bosonic sector as well as the spin sector, and we discuss how such a periodically kicked system relaxes to a thermalized state in accordance with the laws of statistical mechanics.

Fano-Agarwal couplings and non-rotating wave approximation in single-photon timed Dicke subradiance

NASA Astrophysics Data System (ADS)

Mirza, Imran M.; Begzjav, Tuguldur

2016-04-01

Recently a new class of single-photon timed Dicke (TD) subradiant states has been introduced with possible applications in single-photon-based quantum information storage and on demand ultrafast retrieval (Scully M. O., Phys. Rev. Lett., 115 (2015) 243602). However, the influence of any kind of virtual processes on the decay of these new kind of subradiant states has been left as an open question. In the present paper, we focus on this problem in detail. In particular, we investigate how pure Fano-Agarwal couplings and other virtual processes arising from non-rotating wave approximation impact the decay of otherwise sub- and superradiant states. In addition to the overall virtual couplings among all TD states, we also focus on the dominant role played by the couplings between specific TD states.

Henry's law constant for phosphine in seawater: determination and assessment of influencing factors

NASA Astrophysics Data System (ADS)

Fu, Mei; Yu, Zhiming; Lu, Guangyuan; Song, Xiuxian

2013-07-01

The Henry's Law constant ( k) for phosphine in seawater was determined by multiple phase equilibration combined with headspace gas chromatography. The effects of pH, temperature, and salinity on k were studied. The k value for phosphine in natural seawater was 6.415 at room temperature (approximately 23°C). This value increases with increases in temperature and salinity, but no obvious change was observed at different pH levels. At the same temperature, there was no significant difference between the k for phosphine in natural seawater and that in artificial seawater. This implies that temperature and salinity are major determining factors for k in marine environment. Double linear regression with Henry's Law constants for phosphine as a function of temperature and salinity confirmed our observations. These results provide a basis for the measurement of trace phosphine concentrations in seawater, and will be helpful for future research on the status of phosphine in the oceanic biogeochemical cycle of phosphorus.

Structure-activity relationships to estimate the effective Henry's law coefficients of organics of atmospheric interest

NASA Astrophysics Data System (ADS)

Raventos-Duran, Teresa; Valorso, Richard; Aumont, Bernard; Camredon, Marie

2010-05-01

The oxidation of volatile organic compounds emitted in the atmosphere involves complex reaction mechanisms which leads to the formation of oxygenated organic intermediates, usually denoted as secondary organics. The fate of these secondary organics remains poorly quantified due to a lack of information about their speciation, distribution and evolution in the gas and condensed phases. A significant fraction of secondary organics may dissolve into the tropospheric aqueous phase owing to the presence of polar moieties generated during the oxidation processes. The partitioning of organics between the gas and the aqueous atmospheric phases is usually described in the basis of Henry's law. Atmospheric models require a knowledge of the Henry's law coefficient (H) for every water soluble organic species described in the chemical mechanism. Methods that can predict reliable H values for the vast number of organic compounds are therefore required. We have compiled a data set of experimental Henry's law constants for compounds bearing functional groups of atmospheric relevance. This data set was then used to develop GROMHE, a structure activity relationship to predict H values based on a group contribution approach. We assessed its performance with two other available estimation methods. The results show that for all these methods the reliability of the estimates decreases with increasing solubility. We discuss differences between methods and found that GROMHE had greater prediction ability.

A French description of German psychology laboratories in 1893 by Victor Henri, a collaborator of Binet.

PubMed

Nicolas, Serge; Barnes, Marissa E; Murray, David J

2015-05-01

There is a rich tradition of writings about the foundation of psychology laboratories, particularly in the United States but also in France. Various documents exist concerning former German laboratories in American and French literature. But the most interesting French paper was certainly written by a young psychologist named Victor Henri (1872-1940) who was a close collaborator of Alfred Binet (1857-1911) in the 1890s. Visiting various psychology laboratories, he wrote, in 1893, a clear description of the laboratories of Wundt, G. E. Müller, Martius and Ebbinghaus. An English translation is given of Henri's paper and the historical importance of his contribution is here expounded by contrasting the German and French psychologies of the time.

The Rhetoric of Bishop Henry McNeal Turner, Renowned Speaker and Journalist.

ERIC Educational Resources Information Center

Cummings, Melbourne S.

Bishop Henry McNeal Turner, a journalist and speaker, headed a back-to-Africa movement in the second half of the nineteenth century that was one of the first black rhetorical movements to meet the challenges of institutionalized racism in the United States. Turner was a preacher in the African Methodist Episcopal Church, becoming first an elder…

Wildfire rehabilitation success with and without chaining on the Henry Mountains, Utah

Treesearch

Cristina Juran; Bruce A. Roundy; James N. Davis

2008-01-01

We sampled unchained and chained areas in 2004 and 2005 on the Henry Mountains that had been aerially seeded after the Bulldog Fire of 2003. Establishment of seeded grasses was high on unchained and chained areas although chaining increased seeded grass establishment on some sites. Western yarrow established well on unchained areas. Initially, high seedling emergence...

High-order corrections on the laser cooling limit in the Lamb-Dicke regime.

PubMed

Yi, Zhen; Gu, Wen-Ju

2017-01-23

We investigate corrections on the cooling limit of high-order Lamb-Dicke (LD) parameters in the double electromagnetically induced transparency (EIT) cooling scheme. Via utilizing quantum interferences, the single-phonon heating mechanism vanishes and the system evolves to a double dark state, from which we will obtain the mechanical occupation on the single-phonon excitation state. In addition, the further correction induced by two-phonon heating transitions is included to achieve a more accurate cooling limit. There exist two pathways of two-phonon heating transitions: direct two-phonon excitation from the dark state and further excitation from the single-phonon excited state. By adding up these two parts of correction, the obtained analytical predictions show a well consistence with numerical results. Moreover, we find that the two pathways can destructively interfere with each other, leading to the elimination of two-phonon heating transitions and achieving a lower cooling limit.

78 FR 8682 - Culturally Significant Objects Imported for Exhibition Determinations: “Henri Labrouste...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... DEPARTMENT OF STATE [Public Notice 8176] Culturally Significant Objects Imported for Exhibition Determinations: ``Henri Labrouste: Structure Brought to Light'' SUMMARY: Notice is hereby given of the following determinations: Pursuant to the authority vested in me by the Act of October 19, 1965 (79 Stat. 985; 22 U.S.C...

Apportionment of NMHC tailpipe vs non-tailpipe emissions in the Fort McHenry and Tuscarora mountain tunnels

NASA Astrophysics Data System (ADS)

Gertler, Alan W.; Fujita, Eric M.; Pierson, William R.; Wittorff, David N.

Measurements of on-road emissions of non-methane hydrocarbons (NMHCs) were made in the Fort McHenry Tunnel (Baltimore) and Tuscarora Mountain Tunnel (Pennsylvania) during the summer of 1992. Measurements were made during 11 one-hour periods in the Fort McHenry Tunnel and during 11 one-hour periods in the Tuscarora Mountain Tunnel. The observed light-duty fleets were quite new, with a median model year of approximately 1989. Speciated NMHC values were obtained from analyses of canister and Tenax samples, and light-duty speciated emission factors were calculated for the two tunnels. Fuel samples were collected in the area around the tunnels for use in constructing headspace and liquid fuel profiles for the chemical mass balance (CMB) receptor model. Profiles of tailpipe emissions were obtained from the literature. The CMB was used to apportion tailpipe from non-tailpipe emissions. Non-tailpipe sources were found to constitute approximately 15% of the light-duty NMHC emissions. The Federal automotive emission-rate models, MOBILE4.1 and MOBILE5, underpredicted non-tailpipe emissions, assigning approximately 9% and 6.5%, respectively, to non-tailpipe sources. In terms of total absolute emissions, MOBILE5 predictions were approximately a factor of 2 greater than MOBILE4.1 predictions. Both MOBILE4.1 and MOBILE5 underestimated the NMHC emissions in the Fort McHenry Tunnel and overpredicted the NMHC emissions in the Tuscarora Mountain Tunnel. In all cases, the MOBILE models underestimated the absolute value of the non-tailpipe emissions. The ability of the MOBILE models to account for observed emissions when conditions are more variable than those studies in the Fort McHenry and Tuscarora Mountain tunnels is still an open question.

On the relationship between the classical Dicke-Jaynes-Cummings-Gaudin model and the nonlinear Schroedinger equation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Du, Dianlou; Geng, Xue

2013-05-15

In this paper, the relationship between the classical Dicke-Jaynes-Cummings-Gaudin (DJCG) model and the nonlinear Schroedinger (NLS) equation is studied. It is shown that the classical DJCG model is equivalent to a stationary NLS equation. Moreover, the standard NLS equation can be solved by the classical DJCG model and a suitably chosen higher order flow. Further, it is also shown that classical DJCG model can be transformed into the classical Gaudin spin model in an external magnetic field through a deformation of Lax matrix. Finally, the separated variables are constructed on the common level sets of Casimir functions and the generalizedmore » action-angle coordinates are introduced via the Hamilton-Jacobi equation.« less

William Henry Welch (1850–1934): the road to Johns Hopkins

PubMed Central

2011-01-01

William Henry Welch's selection in 1884 as the first faculty member of the new medical school at Johns Hopkins created the invigorating atmosphere that generated the revolutionary changes in medical training and laboratory medicine that transformed medicine in America. Dr. Welch's family traditions, his New England upbringing, Yale education, and German university experience prepared a unique individual to lead American medicine into the 20th century. PMID:21738298

W. Henry Robinson: Popularising astronomy in Victorian Walsall and Birmingham

NASA Astrophysics Data System (ADS)

Williams, S.

William Henry Robinson was one of the most prominent citizens of Walsall, then part of Staffordshire, in the Victorian and Edwardian periods. An influential businessman, he managed to combine printing, publishing, editing a newspaper, writing books and poetry, maintaining a library and retail trading with founding the town's literary institute, and bringing the scientists, explorers, authors and cultural pursuits of the day to his home town. An amateur astronomer in his own right, Robinson was instrumental in setting up the BAA's Midland Branch.

From the "metaphysics of the individual" to the critique of society: on the practical significance of Michel Henry's phenomenology of life.

PubMed

Staudigl, Michael

This essay explores the practical significance of Michel Henry's "material phenomenology." Commencing with an exposition of his most basic philosophical intuition, i.e., his insight that transcendental affectivity is the primordial mode of revelation of our selfhood, the essay then brings to light how this intuition also establishes our relation to both the world and others. Animated by a radical form of the phenomenological reduction, Henry's material phenomenology brackets the exterior world in a bid to reach the concrete interior transcendental experience at the base of all exteriority. The essay argues that this "counter reduction," designed as a practical orientation to the world, suspends all traditional parameters of onto(theo)logical individuation in order to rethink subjectivity in terms of its transcendental corporeality, i.e., in terms of the invisible display of "affective flesh." The development of this "metaphysics of the individual" anchors his "practical philosophy" as he developed it-under shifting accents-throughout his oeuvre. In particular, the essay brings into focus Henry's reflections on modernity, the industry of mass culture and their "barbaric" movements. The essay briefly puts these cultural and political areas of Henry's of thinking into contact with his late "theological turn," i.e., his Christological account of Life and the (inter)subjective self-realization to which it gives rise.

Parity oscillations and photon correlation functions in the Z2-U (1 ) Dicke model at a finite number of atoms or qubits

NASA Astrophysics Data System (ADS)

Yi-Xiang, Yu; Ye, Jinwu; Zhang, CunLin

2016-08-01

Four standard quantum optics models, that is, the Rabi, Dicke, Jaynes-Cummings, and Tavis-Cummings models, were proposed by physicists many decades ago. Despite their relative simple forms and many previous theoretical works, their physics at a finite N , especially inside the superradiant regime, remain unknown. In this work, by using the strong-coupling expansion and exact diagonalization (ED), we study the Z2-U(1 ) Dicke model with independent rotating-wave coupling g and counterrotating-wave coupling g' at a finite N . This model includes the four standard quantum optics models as its various special limits. We show that in the superradiant phase, the system's energy levels are grouped into doublets with even and odd parity. Any anisotropy β =g'/g ≠1 leads to the oscillation of parities in both the ground and excited doublets as the atom-photon coupling strength increases. The oscillations will be pushed to the infinite coupling strength in the isotropic Z2 limit β =1 . We find nearly perfect agreement between the strong-coupling expansion and the ED in the superradiant regime when β is not too small. We also compute the photon correlation functions, squeezing spectrum, and number correlation functions that can be measured by various standard optical techniques.

Actively Experiencing Shakespeare: Students "Get on Their Feet" for "Henry IV, Part One."

ERIC Educational Resources Information Center

Meyer, Herbert M.; Thomsen, Lee

1999-01-01

Discusses how a literature and multimedia course for 11th and 12th graders used active-learning experiences to engage students with Shakespeare's "Henry IV, Part One." Describes how shouting Hal's soliloquy; constructing a chart of character relations; rewriting a scene in their own words; performing, filming, and critiquing a scene; and…

Henri Ey's neojacksonism and the psychopathology of disintegrated mind.

PubMed

Farina, Benedetto; Ceccarelli, Maurizio; Di Giannantonio, Massimo

2005-01-01

The French psychiatrist Henri Ey developed his organo-dynamic theory of the mind function and consciousness 50 years ago incorporating Hughling Jackson's thinking, along with psychiatric and philosophical theorizations by Janet and Bergson. This model has not received the attention it deserved, but recent advances in neuroscience rekindled interest for Ey's theory. By overcoming the Cartesian mind-body dualism and treating the mind-body unit as an inseparable whole, this model opens the way for the integrated treatment of mental disorders. Ey's conceptualization of consciousness as being simultaneously both synchronous and diachronic anticipates current theories of consciousness (Damasio, Edelman, Mesulam).

Superfund Record of Decision (EPA Region 3): William Dick Lagoons, West Caln Township, Chester County, PA. (First remedial action), June 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-09-28

The 4.4-acre William Dick Lagoons site is a chemical wastewater disposal site in West Caln Township, Chester County, Pennsylvania. An estimated 30 residences located within 1,000 feet of the site use private wells for their drinking water supply. Two other Superfund sites are near the site. From the 1950's to 1970, Mr. William Dick used the lagoons to dispose of wastewater left from cleaning the interiors of chemical and petroleum tank trailers owned primarily by Chemical Leaman Tank Lines, (CLTL), and residual chemical products. Later in 1970, vandalism caused the release of an estimated 300,000 gallons of wastewater into Birchmore » Run, a tributary of the West Branch of Brandywine Creek. As a result of this discharge, more than 2,600 fish died, and water supplies that used Brandywine Creek as a water source were closed. The Record of Decision (ROD) provides an interim remedy and addresses contaminated residential water as Operable Unit 1 (OU1) and ground water as OU2. A future ROD will address source control and will provide a remedy for the cleanup of contaminated soil. The primary contaminants of concern affecting the ground water are VOCs including benzene, PCE, and TCE; other organics including phenols; and metals. The selected remedial action for the site is included.« less

Real-time observation of fluctuations at the driven-dissipative Dicke phase transition

PubMed Central

Brennecke, Ferdinand; Mottl, Rafael; Baumann, Kristian; Landig, Renate; Donner, Tobias; Esslinger, Tilman

2013-01-01

We experimentally study the influence of dissipation on the driven Dicke quantum phase transition, realized by coupling external degrees of freedom of a Bose–Einstein condensate to the light field of a high-finesse optical cavity. The cavity provides a natural dissipation channel, which gives rise to vacuum-induced fluctuations and allows us to observe density fluctuations of the gas in real-time. We monitor the divergence of these fluctuations over two orders of magnitude while approaching the phase transition, and observe a behavior that deviates significantly from that expected for a closed system. A correlation analysis of the fluctuations reveals the diverging time scale of the atomic dynamics and allows us to extract a damping rate for the external degree of freedom of the atoms. We find good agreement with our theoretical model including dissipation via both the cavity field and the atomic field. Using a dissipation channel to nondestructively gain information about a quantum many-body system provides a unique path to study the physics of driven-dissipative systems. PMID:23818599

Neostusakia, a new name for preoccupied Stusakia Kment and Henry, 2008 (Hemiptera: Heteroptera: Berytidae)

USDA-ARS?s Scientific Manuscript database

A case of homonymy in the heteropteran family Berytidae is addressed. The genus Stusakia Kment and Henry, 2008 (Hemiptera) is preoccupied by Stusakia Frýda, 1998 (Mollusca: Gastropoda). As a consequence, the replacement name Neostusakia, new name, is proposed. In addition, the only two included s...

Fin-de-Siecle Advances in Neuroeducation: Henry Herbert Donaldson and Reuben Post Halleck

ERIC Educational Resources Information Center

Theodoridou, Zoe D.; Triarhou, Lazaros C.

2009-01-01

This article focuses on two early attempts at bridging neuroscience and education, made by Henry Herbert Donaldson (1857-1938), a neurologist, and Reuben Post Halleck (1859-1936), an educator. Their works, respectively entitled "The Growth of the Brain: A Study of the Nervous System in Relation to Education" (1895) and "The Education of the…

A highly thermostable alkaline cellulase-free xylanase from thermoalkalophilic Bacillus sp. JB 99 suitable for paper and pulp industry: purification and characterization.

PubMed

Shrinivas, Dengeti; Savitha, Gunashekaran; Raviranjan, Kumar; Naik, Gajanan Ramchandra

2010-11-01

A highly thermostable alkaline xylanase was purified to homogeneity from culture supernatant of Bacillus sp. JB 99 using DEAE-Sepharose and Sephadex G-100 gel filtration with 25.7-fold increase in activity and 43.5% recovery. The molecular weight of the purified xylanase was found to be 20 kDA by SDS-PAGE and zymogram analysis. The enzyme was optimally active at 70 °C, pH 8.0 and stable over pH range of 6.0-10.0.The relative activity at 9.0 and 10.0 were 90% and 85% of that of pH 8.0, respectively. The enzyme showed high thermal stability at 60 °C with 95% of its activity after 5 h. The K (m) and V (max) of enzyme for oat spelt xylan were 4.8 mg/ml and 218.6 µM min(-1) mg(-1), respectively. Analysis of N-terminal amino acid sequence revealed that the xylanase belongs to glycosyl hydrolase family 11 from thermoalkalophilic Bacillus sp. with basic pI. Substrate specificity showed a high activity on xylan-containing substrate and cellulase-free nature. The hydrolyzed product pattern of oat spelt xylan on thin-layer chromatography suggested xylanase as an endoxylanase. Due to these properties, xylanase from Bacillus sp. JB 99 was found to be highly compatible for paper and pulp industry.

Non-singular Brans–Dicke collapse in deformed phase space

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rasouli, S.M.M., E-mail: mrasouli@ubi.pt; Centro de Matemática e Aplicações; Physics Group, Qazvin Branch, Islamic Azad University, Qazvin

2016-12-15

We study the collapse process of a homogeneous perfect fluid (in FLRW background) with a barotropic equation of state in Brans–Dicke (BD) theory in the presence of phase space deformation effects. Such a deformation is introduced as a particular type of non-commutativity between phase space coordinates. For the commutative case, it has been shown in the literature (Scheel, 1995), that the dust collapse in BD theory leads to the formation of a spacetime singularity which is covered by an event horizon. In comparison to general relativity (GR), the authors concluded that the final state of black holes in BD theorymore » is identical to the GR case but differs from GR during the dynamical evolution of the collapse process. However, the presence of non-commutative effects influences the dynamics of the collapse scenario and consequently a non-singular evolution is developed in the sense that a bounce emerges at a minimum radius, after which an expanding phase begins. Such a behavior is observed for positive values of the BD coupling parameter. For large positive values of the BD coupling parameter, when non-commutative effects are present, the dynamics of collapse process differs from the GR case. Finally, we show that for negative values of the BD coupling parameter, the singularity is replaced by an oscillatory bounce occurring at a finite time, with the frequency of oscillation and amplitude being damped at late times.« less

Non-singular Brans-Dicke collapse in deformed phase space

NASA Astrophysics Data System (ADS)

Rasouli, S. M. M.; Ziaie, A. H.; Jalalzadeh, S.; Moniz, P. V.

2016-12-01

We study the collapse process of a homogeneous perfect fluid (in FLRW background) with a barotropic equation of state in Brans-Dicke (BD) theory in the presence of phase space deformation effects. Such a deformation is introduced as a particular type of non-commutativity between phase space coordinates. For the commutative case, it has been shown in the literature (Scheel, 1995), that the dust collapse in BD theory leads to the formation of a spacetime singularity which is covered by an event horizon. In comparison to general relativity (GR), the authors concluded that the final state of black holes in BD theory is identical to the GR case but differs from GR during the dynamical evolution of the collapse process. However, the presence of non-commutative effects influences the dynamics of the collapse scenario and consequently a non-singular evolution is developed in the sense that a bounce emerges at a minimum radius, after which an expanding phase begins. Such a behavior is observed for positive values of the BD coupling parameter. For large positive values of the BD coupling parameter, when non-commutative effects are present, the dynamics of collapse process differs from the GR case. Finally, we show that for negative values of the BD coupling parameter, the singularity is replaced by an oscillatory bounce occurring at a finite time, with the frequency of oscillation and amplitude being damped at late times.

Evaluation and Prediction of Henry’s Law Constants and Aqueous Solubilities for Solvents and Hydrocarbon Fuel Components. Volume 2. Experimental Henry’s Law Data

DTIC Science & Technology

1987-09-01

Pollutants by Gas Chromatographic Headspace Analysis. J. Chrom . 260:23-32. Miller, R. E. 1984. Confidence Intervals and Hypothesis Tests. Chem. Engr...tabulation of the injection peak areas, Henry’s law constant estimates, and Coefficient of Variation (COV) values for the component at five temperatures...I 15.1897 (4) I 14.5788 I 19.7121 1 16 6428 Injection: (1) 1 16158 I 2596 38628 Peak Area] (2) 1 154846 1 281438 1 261148 (3) 4673 1 64736 1 63322 (4

Neoliberalism, Democracy and the University as a Public Sphere: An Interview with Henry A. Giroux

ERIC Educational Resources Information Center

Harper, Victoria

2014-01-01

"Truthout" contributor, director of "Truthout's" Public Intellectual Project (truth-out.org/public-intellectual-project) and Truthout board member Henry A. Giroux responds to questions about how the excesses of neoliberal politics have reshaped and subverted the democratic mission of higher education.

Assessing the Teaching and Student Learning Outcomes of the Katz/Henry Faculty Development Model.

ERIC Educational Resources Information Center

Finkelstein, Martin

The impact of the Katz/Henry Faculty Development Model on teaching behaviors and student learning outcomes was assessed with 24 faculty members at 4 institutions in New Jersey. This model, known as "Partners in Learning" involved: faculty pairs who observe one another's class, partner meetings to discuss shared experience in the…

The Politics of Knowledge and the Revitalization of American Democracy: A Response to Henry Giroux's "The University in Chains: Confronting the Military-Industrial-Academic Complex"

ERIC Educational Resources Information Center

Fraser, Cary

2009-01-01

This article presents the author's response to Henry Giroux's "The University in Chains: Confronting the Military-Industrial-Academic Complex." Henry Giroux has written a provocative assessment of the contemporary challenges facing the United States as a society, which over the course of the 20th century had assumed the role of leader and exemplar…

BUBBLE STRIPPING TO DETERMINE HYDROGEN CONCENTRATIONS IN GROUND WATER: A PRACTICAL APPLICATION OF HENRY'S LAW

EPA Science Inventory

The Bubble Stripping Method is a chemical testing method that operates on the principle of Henry's Law. It is useful for determining concentrations of hydrogen in well water, and it is capable of detecting concentrations on the order of nanomoles per liter. The method provides ...

Hispanic Storyteller: Unity through the Use of Narrative in the Speaking of Henry Cisneros.

ERIC Educational Resources Information Center

Hanson, Trudy L.

Henry Cisneros, speaking on the theme, "the colorful past and promising future of Hispanic heroes in Texas," in Amarillo, Texas, on February 7, 1989, was successful in eliciting a positive response from his Anglo/Hispanic audience. An analysis of Cisneros' use of narrative demonstrates its effectiveness in leading to a feeling of…

[The electric furnace of Henri Moissan at one hundred years: connection with the electric furnace, the solar furnace, the plasma furnace?].

PubMed

Royère, C

1999-03-01

The trace of Henri Moissan's pioneer work 100 years ago is clearly evidenced by an overview of achievements in high temperature devices; 1987: "Le four électrique" by Henri Moissan; 1948-1952: "High temperature heating in a cavity rotary kiln using focusing of solar radiation" by Félix Trombe; 1962: "The cavity rotary kiln using focused solar radiation jointly with a plasma gun" by Marc Foëx; 1970: "The rotary kiln with two plasma guns and arc transfer" by Marc Foëx; 1984: "The plasma furnace" by Electricité de France (EDF) at Renardières; 1997: "The plasma furnace" by the Atomic Energy Center (CEA) at Cadarache, the VULCANO program. The first part of this contribution is devoted to Henri Moissan. Re-reading his early book on the electric furnace, especially the first chapter and the sections on silica, carbon vapor and experiments performed in casting molten metal--the conclusions are outstanding--provides modern readers with an amazing insight into future developments. The last two parts are devoted to Félix Trombe and Marc Foëx, tracing the evolution of high temperature cavity processus leading to the solar furnace and the present day plasma furnace at the CEA. Focus is placed on research conducted by the French National Center for Scientific Research (CNRS) with the solar and plasma furnaces at Odeillo. The relationships with Henri Moissan's early work are amazing, offering a well deserved homage to this pioneer researcher.

Henry Giroux and the Politics of Higher Education under George W. Bush: An Interview

ERIC Educational Resources Information Center

Pozo, Mike Alexander

2005-01-01

In May of 2004 Henry Giroux, a creator of the field of critical pedagogy and a leading advocate for young people, democracy, and education in the United States, reluctantly left Penn State University after twelve years as a Distinguished Professor in the education department. He has been a critic of the corporatization of and conservative…

Modified Holographic Ricci Dark Energy in Chameleon Brans-Dicke Cosmology and Its Thermodynamic Consequence

NASA Astrophysics Data System (ADS)

Jawad, A.; Chattopadhyay, S.; Bhattacharya, S.; Pasqua, A.

2015-04-01

The objective of this paper is to discuss the Chameleon Brans-Dicke gravity with non-minimally matter coupling of scalar field. We take modified Holographic Ricci dark energy model in this gravity with its energy density in interaction with energy density of cold dark matter. We assume power-law ansatz for scale factor and scalar field to discuss potential as well as coupling functions in the evolving universe. These reconstructed functions are plotted versus scalar field and time for different values of power component of scale factor n. We observe that potential and coupling functions represent increasing behavior, in particular, consistent results for a specific value of n. Finally, we have examined validity of the generalized second law of thermodynamics and we have observed its validity for all values of n. The financial Supported from Department of Science and Technology, Govt. of India under Project Grant No. SR/FTP/PS-167/2011 is thankfully acknowledged by SC

Three Averaging Techniques for Reduction of Antenna Temperature Variance Measured by a Dicke Mode, C-Band Radiometer

NASA Technical Reports Server (NTRS)

Mackenzie, Anne I.; Lawrence, Roland W.

2000-01-01

As new radiometer technologies provide the possibility of greatly improved spatial resolution, their performance must also be evaluated in terms of expected sensitivity and absolute accuracy. As aperture size increases, the sensitivity of a Dicke mode radiometer can be maintained or improved by application of any or all of three digital averaging techniques: antenna data averaging with a greater than 50% antenna duty cycle, reference data averaging, and gain averaging. An experimental, noise-injection, benchtop radiometer at C-band showed a 68.5% reduction in Delta-T after all three averaging methods had been applied simultaneously. For any one antenna integration time, the optimum 34.8% reduction in Delta-T was realized by using an 83.3% antenna/reference duty cycle.

[Henry Beecher and medical science: the 50th anniversary of a famous article].

PubMed

Jacobs, N; Huisman, F G

2017-01-01

In 2016, it had been exactly half a century ago that Henry Beecher published his article 'Ethics and clinical research' in The New England Journal of Medicine. Today, this article is considered a turning point in the history of medical research ethics. On the occasion of the fiftieth anniversary of this famous article, we are looking back on this turbulent period in the history of medicine.

James Paget Henry--a retrospective.

PubMed

Meehan, J P; Meehan, W P

1997-01-01

James Paget Henry really began his productive research career at the outset of the second world war. His studies of acceleration and the anoxia of high altitude were supported by the development of then new techniques of measuring and recording critical physiologic parameters such as vascular pressures, respiratory functions and haemoglobin saturation. His inquisitive mind made productive use of the instruments that had to be made by skilled instrument makers working in university shops. Much of this instrumentation has now found its way into the clinical arena where it is now the main armamentarium of cardiac diagnostic and respiratory function laboratories. His work in the space program preceeded that of the Russians but did not get recognition until Sputnik awakened the world to the possibilities of space flight. His development of the concept of a cardiovascular basis for fluid volume control and the supportive investigative work undertaken constitute a milestone in the annals of experimental physiology. The chimpanzees used in Project Mercury were found to be hypertensive which was related to the method of capture used by the commercial suppliers. This lead Jim to study the effect of early experience on resting blood pressure, an effort that soon developed into provocative studies of the biological basis of the stress response.

The Henry Cecil Ranson McBay Chair in Space Science

NASA Technical Reports Server (NTRS)

Bota, Kofi B.; King, James, Jr.

1999-01-01

The goals and objectives of the Henry Cecil Ransom McBay Chair in Space Sciences were to: (1) provide leadership in developing and expanding Space Science curriculum; (2) contribute to the research and education endeavors of NASA's Mission to Planet Earth program; (3) expand opportunities for education and hands-on research in Space and Earth Sciences; (4) enhance scientific and technological literacy at all educational levels and to increase awareness of opportunities in the Space Sciences; and (5) develop a pipeline, starting with high school, of African American students who will develop into a cadre of well-trained scientists with interest in Space Science Research and Development.

The Heuristic Method, Precursor of Guided Inquiry: Henry Armstrong and British Girls' Schools, 1890-1920

ERIC Educational Resources Information Center

Rayner-Canham, Geoff; Rayner-Canham, Marelene

2015-01-01

Though guided-inquiry learning, discovery learning, student-centered learning, and problem-based learning are commonly believed to be recent new approaches to the teaching of chemistry, in fact, the concept dates back to the late 19th century. Here, we will show that it was the British chemist, Henry Armstrong, who pioneered this technique,…

Pigeon pea waste as a novel, inexpensive, substrate for production of a thermostable alkaline protease from thermoalkalophilic Bacillus sp. JB-99.

PubMed

Johnvesly, B; Manjunath, B R; Naik, G R

2002-03-01

Thermoalkaliphilic Bacillus sp. JB-99 was grown in a 250 ml Erlenmeyer flask containing 50 ml medium containing (g/l) Pigeon pea waste 10; NaNO3, 5.0; K2HPO4, 5.0; MgSO4 x 2H2O, 0.2 and Na2CO3, 10.0. Incubations were carried out at 50 degrees C on a rotary incubator shaker for 15 h. A high level of extra cellular thermostable protease activity was observed after 24 h incubation. The optimum temperature and pH for activity were 70 degrees C and 11, respectively, so this enzyme showed stable activity at high temperature and under alkaline conditions.

Documentation for the machine-readable version of the Henry Draper Catalogue (edition 1985)

NASA Technical Reports Server (NTRS)

Roman, N. G.; Warren, W. H., Jr.

1985-01-01

An updated, corrected and extended machine-readable version of the catalog is described. Published and unpublished errors discovered in the previous version was corrected; letters indicating supplemental stars in the BD have been moved to a new byte to distinguish them from double-star components; and the machine readable portion of The Henry Draper Extension (HDE) (HA 100) was converted to the same format as the main catalog, with additional data added as necessary.

Dynamics of coherent states in regular and chaotic regimes of the non-integrable Dicke model

NASA Astrophysics Data System (ADS)

Lerma-Hernández, S.; Chávez-Carlos, J.; Bastarrachea-Magnani, M. A.; López-del-Carpio, B.; Hirsch, J. G.

2018-04-01

The quantum dynamics of initial coherent states is studied in the Dicke model and correlated with the dynamics, regular or chaotic, of their classical limit. Analytical expressions for the survival probability, i.e. the probability of finding the system in its initial state at time t, are provided in the regular regions of the model. The results for regular regimes are compared with those of the chaotic ones. It is found that initial coherent states in regular regions have a much longer equilibration time than those located in chaotic regions. The properties of the distributions for the initial coherent states in the Hamiltonian eigenbasis are also studied. It is found that for regular states the components with no negligible contribution are organized in sequences of energy levels distributed according to Gaussian functions. In the case of chaotic coherent states, the energy components do not have a simple structure and the number of participating energy levels is larger than in the regular cases.

Development of a Career Student Guide for the Tech Prep Program for Henry County High School.

ERIC Educational Resources Information Center

Winchester, Ruth Ann

This practicum report describes the research conducted in preparation for developing a career student guide to acquaint students attending Henry County High School (HCHS) in McDonough, Georgia, with the school's new tech prep program. Chapters 1 and 2 contain background information about HCHS' tech prep program and a review of literature regarding…

anti-Selective Asymmetric Henry Reaction Catalyzed by a Heterobimetallic Cu-Sm-Aminophenol Sulfonamide Complex.

PubMed

Li, Yang; Deng, Ping; Zeng, Youmao; Xiong, Yan; Zhou, Hui

2016-04-01

A novel heterobimetallic Cu/Sm/aminophenol sulfonamide complex has been developed by a convenient one-pot method for the anti-selective asymmetric Henry reaction. The corresponding anti-β-nitro alcohols are obtained in up to 99% yield, >30:1 dr, and 98% ee. The results of control experiments and ESI-MS analysis of the complex indicate that the monomeric bimetallic Cu/Sm/1 complex would be the active species.

Victor Henri: 111 years of his equation.

PubMed

Cornish-Bowden, Athel; Mazat, Jean-Pierre; Nicolas, Serge

2014-12-01

Victor Henri's great contribution to the understanding of enzyme kinetics and mechanism is not always given the credit that it deserves. In addition, his earlier work in experimental psychology is totally unknown to biochemists, and his later work in spectroscopy and photobiology almost equally so. Applying great rigour to his analysis he succeeded in obtaining a model of enzyme action that explained all of the observations available to him, and he showed why the considerable amount of work done in the preceding decade had not led to understanding. His view was that only physical chemistry could explain the behaviour of enzymes, and that models should be judged in accordance with their capacity not only to explain previously known facts but also to predict new observations against which they could be tested. The kinetic equation usually attributed to Michaelis and Menten was in reality due to him. His thesis of 1903 is now available in English. Copyright © 2014 Elsevier B.V. and Société française de biochimie et biologie Moléculaire (SFBBM). All rights reserved.

76 FR 63906 - Henry Gordy International, Inc., Provisional Acceptance of a Settlement Agreement and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-14

...'' (``Target Set''). Each Target Set consisted of the following: A toy gun; soft, pliable, plastic toy darts... report of a death involving a Target Set on or about May 1, 2006, after an 8-year-old boy choked on a dart and died on March 9, 2006. 8. In response to the death reported on or about May 1, 2006, Henry...

Copper-Catalyzed Enantioselective Henry Reaction of β,γ-Unsaturated α-Ketoesters with Nitromethane in Water.

PubMed

Li, Yanan; Huang, Yekai; Gui, Yang; Sun, Jianan; Li, Jindong; Zha, Zhenggen; Wang, Zhiyong

2017-12-01

A highly enantioselective Henry reaction of β,γ-unsaturated α-ketoesters with nitromethane in water by virtue of chiral copper complexes has been developed. A series of unsaturated β-nitro-α-hydroxy esters bearing tetrasubstituted carbon stereocenters were obtained exclusively with high yields and excellent enantioselectivities. This method could avoid tedious anaerobic anhydrous manipulation and reduce the environmental pollution caused by organic solvents.

[Henri Atlan's levels of ethics and the challenge of the "fourth level"].

PubMed

Aleksandrowicz, Ana Maria Coutinho

2008-01-01

This article presents the ideas on ethics by the contemporary French biophysicist and Spinozist philosopher Henri Atlan, based on his singular epistemological position, in constant transit between naturalistic philosophy (in alliance with cognitive sciences) and his refusal to a natural foundations of ethics. It underlines Atlan's defense of casuistry towards bioethics dilemmas and associates it to his proposal of different levels of ethics. The text introduces a reflection concerning Atlan's ideas about the possible passage between the third and the fourth levels of ethics, stressing its positive impact in individuals and social groups' life quality.

Superfund record of decision (EPA Region 3): William Dick Lagoons, West Caln Township, Chester County, PA, March 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-03-31

This decision document presents the selected remedial action for Operable Unit 3 of the William Dick Lagoons Site (Site), in West Caln Township, Pennsylvania. The remedy described in this Record of Decision is for Operable Unit 3 at the Site. The remedy selected for Operable Unit 3 will reduce the concentrations of hazardous substances in the Site soils so that leaching of contaminants into the groundwater will be minimized. Reduction of the volatile organic compounds and semi-volatile organic compounds in the soils is necessary in order the groundwater will not continue to be impacted above acceptable levels. In addition, themore » installation of a vegetative soil cover or multi-layer cap will prevent the surrounding community from exposure to Site-related contaminants through inhalation, ingestion, and dermal contact.« less

On New Rhetoric, John Henry Newman and the Language of Metaphors: Implications for Branding Higher Education

ERIC Educational Resources Information Center

Lawler-Brunner, Jennifer Lynne

2012-01-01

This project interprets how John Henry Newman's (1801-1890) system of thought informs the philosophical and theoretical grounds for rhetorical praxis in the marketplace. His seminal lessons in "An Essay in Aid of a Grammar of Assent" (1870) and "The Idea of a University" (1873 ed.) demonstrate the metaphoric power of words…

Isolation of Strain MLTeJB From Mono Lake, California, a Dissimilatory Tellurite Respiring Prokaryote.

NASA Astrophysics Data System (ADS)

Baesman, S. M.; Oremland, R. S.

2007-12-01

Previous investigations on the dissimilatory reduction of Te-oxyanions have been constrained by the inhibtory effects of circa 1.0 mM concentrations of either Te(IV) or Te(VI) upon growth of established cultures. Therefore we initiated new enrichments using anoxic Mono Lake mud supplemented with 10 mM Te(IV) as the electron acceptor and lactate as the electron donor. Sediments turned black with time owing to the formation of Te(0), microscopic examination of which confirmed the presence of both shards, rosettes, and nanospheres of Te(0). The enrichment was subcultured several times in liquid medium and then streaked onto solid medium and incubated in an anaerobic chamber. Isolated black colonies were re-streaked several times, and thence inoculated into liquid medium. However, growth in liquid medium required the presence of a small amount of solid phase, which included a plug of either agar, phytagel, or glass beads. Growth resulted in oxidation of lactate to acetate, formate and CO2 with the reduction of Te(IV) to Te(0). The isolate, strain MLTeJB was a non-motile rod that stained Gram positive, and formed copious exogenous deposits of Te(0) nano-shards and rosettes. Further details on the physiology of this organism will be presented.

Combating child obesity: impact of HENRY on parenting and family lifestyle.

PubMed

Willis, T A; George, J; Hunt, C; Roberts, K P J; Evans, C E L; Brown, R E; Rudolf, M C J

2014-10-01

One-quarter of children in England are overweight/obese at school entry. We investigated the impact of a programme designed to provide parents of infants and preschool children with the skills required for a healthier family lifestyle. A cohort of families was followed across the 8-week HENRY (Health Exercise Nutrition for the Really Young) parent course at nine locations in England. Seventy-seven parents enrolled on the course, of which 71 agreed to complete questionnaires addressing eating behaviours, dietary intake and parental self-efficacy. Pre- and post-course data was available from 60 (84.5%) parents (8-week follow-up data from 58 parents) and was analysed using repeated measures analyses. Significant changes were observed, with most sustained at follow-up. Parents reported increased self-efficacy and ability to encourage good behaviour (P < 0.001). Increased consumption of fruits and vegetables was reported in both children and adults, together with reduced consumption of sweets, cakes and fizzy drinks in adults (all P < 0.01). There were also positive changes in eating behaviours (e.g., frequency of family mealtimes and eating while watching television or in response to negative emotion [P < 0.01] ) and reduced screen time in adults (P < 0.001). The results build upon earlier evaluation, indicating that the HENRY intervention has a beneficial impact upon the families of infants and preschool children. Furthermore, the findings suggest that positive changes inspired by the programme can be maintained beyond its completion. Such changes may serve to protect against later obesity. © 2013 The Authors. Pediatric Obesity © 2013 International Association for the Study of Obesity.

Speculative Truth - Henry Cavendish, Natural Philosophy, and the Rise of Modern Theoretical Science

NASA Astrophysics Data System (ADS)

McCormmach, Russell

2004-03-01

With a never-before published paper by Lord Henry Cavendish, as well as a biography on him, this book offers a fascinating discourse on the rise of scientific attitudes and ways of knowing. A pioneering British physicist in the late 18th and early 19th centuries, Cavendish was widely considered to be the first full-time scientist in the modern sense. Through the lens of this unique thinker and writer, this book is about the birth of modern science.

Disposable Youth/Damaged Democracy: Youth, Neoliberalism, and the Promise of Pedagogy in the Work of Henry Giroux

ERIC Educational Resources Information Center

Robbins, Christopher G.

2012-01-01

Perhaps more extensively and provocatively than any other contemporary theorist, Henry Giroux has theorized the relationship between youth and democratic public life. Beginning arguably with his first book, Ideology, Culture, and the Process of Schooling (Temple University Press, 1981), and continuing across a number of critically acclaimed works…

Partition coefficients for REE between garnets and liquids - Implications of non-Henry's Law behaviour for models of basalt origin and evolution

NASA Technical Reports Server (NTRS)

Harrison, W. J.

1981-01-01

An experimental investigation of Ce, Sm and Tm rare earth element (REE) partition coefficients between coexisting garnets (both natural and synthetic) and hydrous liquids shows that Henry's Law may not be obeyed over a range of REE concentrations of geological relevance. Systematic differences between the three REE and the two garnet compositions may be explained in terms of the differences between REE ionic radii and those of the dodecahedral site into which they substitute, substantiating the Harrison and Wood (1980) model of altervalent substitution. Model calculations demonstrate that significant variation can occur in the rare earth contents of melts produced from a garnet lherzolite, if Henry's Law partition coefficients do not apply for the garnet phase.

Henri Wallon's Theory of Early Child Development: The Role of Emotions

PubMed

Veer

1996-12-01

The present paper gives an account of part of the stage theory of early child development of the French theorist Henri Wallon (1879-1962). Unlike his contemporary Jean Piaget, Wallon concentrated his efforts upon a description of the child's emotional development and the role emotions play in establishing the bond between child and caregiver. The description of Wallon's stage theory is preceded by biographical information and a presentation of his methodological views. It is argued that Wallon's theory is unique in its focus, exerted influence upon theorists such as Lev Vygotsky, and is basically compatible with modern insights about the nature of child development and the growth of intersubjectivity.

VIDEO: Dr. Henry Rodriguez - Proteogenomics in Cancer Medicine | Office of Cancer Clinical Proteomics Research

Cancer.gov

Dr. Henry Rodriguez, director of the Office of Cancer Clinical Proteomics Research (OCCPR) at NCI, speaks with ecancer television at WIN 2017 about the translation of the proteins expressed in a patient's tumor into a map for druggable targets. By combining genomic and proteomic information (proteogenomics), leading scientists are gaining new insights into ways to detect and treat cancer due to a more complete and unified understanding of complex biological processes.

"Undoubtedly a Powerful Influence": Victor Henry's "Antinomies linguistiques" (1896) with an Annotated Translation of the First Chapter.

ERIC Educational Resources Information Center

Joseph, John E.

1996-01-01

Discusses Victor Henry's innovative presentation of some underlying contradictions in the premises on which linguistics is founded, cast in the Kantian form of antinomies. The review argues that no science remains more strongly contested than linguistics, a science whose origins are paradoxical and that contains outdated concepts. (30 references)…

All Are Worthy to Know the Earth: Henry De la Beche and the Origin of Geological Literacy

ERIC Educational Resources Information Center

Clary, Renee M.; Wandersee, James H.

2009-01-01

Henry T. De la Beche (1796-1855) began his geological career within an elite circle (Geological Society of London, 1817; FRS, 1819), collaborating with influential gentlemen geologists and publishing original research. When his independent income dwindled, De la Beche managed to secure governmental funding for his mapping projects. This led to…

Quantum phase transitions of light in a dissipative Dicke-Bose-Hubbard model

NASA Astrophysics Data System (ADS)

Wu, Ren-Cun; Tan, Lei; Zhang, Wen-Xuan; Liu, Wu-Ming

2017-09-01

The impact that the environment has on the quantum phase transition of light in the Dicke-Bose-Hubbard model is investigated. Based on the quasibosonic approach, mean-field theory, and perturbation theory, the formulation of the Hamiltonian, the eigenenergies, and the superfluid order parameter are obtained analytically. Compared with the ideal cases, the order parameter of the system evolves with time as the photons naturally decay in their environment. When the system starts with the superfluid state, the dissipation makes the photons more likely to localize, and a greater hopping energy of photons is required to restore the long-range phase coherence of the localized state of the system. Furthermore, the Mott lobes depend crucially on the numbers of atoms and photons (which disappear) of each site, and the system tends to be classical with the number of atoms increasing; however, the atomic number is far lower than that expected under ideal circumstances. As there is an inevitable interaction between the coupled-cavity array and its surrounding environment in the actual experiments, the system is intrinsically dissipative. The results obtained here provide a more realistic image for characterizing the dissipative nature of quantum phase transitions in lossy platforms, which will offer valuable insight into quantum simulation of a dissipative system and which are helpful in guiding experimentalists in open quantum systems.

Stopping time: Henry Fox Talbot and the origins of freeze-frame photography.

PubMed

Ramalingam, Chitra

2008-09-01

As an image-making tool for scientists studying the transient, instantaneous photography has long been seen as opening up a visual realm previously inaccessible to the inferior testimony of the human eye. But when photographic pioneer Henry Fox Talbot took the first photograph of a moving object by the light of an electric spark in 1851, he was guided by existing visual practices designed to create instantaneous vision in the eye itself. Exploring the background behind the peculiar subject of his experiment - a mechanically spinning disc - reveals a hidden prehistory of spark-illuminated photography: physicists' pre-photographic techniques for stopping time.

"Young People Are No Longer at Risk--They Are the Risk": Henry Giroux's "Youth in a Suspect Society"

ERIC Educational Resources Information Center

McClennen, Sophia A.

2012-01-01

This article analyzes Henry Giroux's recent book Youth in a Suspect Society: democracy or disposability? (Palgrave, 2009) and situates it within his post-9/11 critical interventions. Giroux has focused his recent work on theorizing, critiquing and challenging the confluence of militarization, corporatization and right-wing ideology that has…

Inverse modeling for seawater intrusion in coastal aquifers: Insights about parameter sensitivities, variances, correlations and estimation procedures derived from the Henry problem

USGS Publications Warehouse

Sanz, E.; Voss, C.I.

2006-01-01

Inverse modeling studies employing data collected from the classic Henry seawater intrusion problem give insight into several important aspects of inverse modeling of seawater intrusion problems and effective measurement strategies for estimation of parameters for seawater intrusion. Despite the simplicity of the Henry problem, it embodies the behavior of a typical seawater intrusion situation in a single aquifer. Data collected from the numerical problem solution are employed without added noise in order to focus on the aspects of inverse modeling strategies dictated by the physics of variable-density flow and solute transport during seawater intrusion. Covariances of model parameters that can be estimated are strongly dependent on the physics. The insights gained from this type of analysis may be directly applied to field problems in the presence of data errors, using standard inverse modeling approaches to deal with uncertainty in data. Covariance analysis of the Henry problem indicates that in order to generally reduce variance of parameter estimates, the ideal places to measure pressure are as far away from the coast as possible, at any depth, and the ideal places to measure concentration are near the bottom of the aquifer between the center of the transition zone and its inland fringe. These observations are located in and near high-sensitivity regions of system parameters, which may be identified in a sensitivity analysis with respect to several parameters. However, both the form of error distribution in the observations and the observation weights impact the spatial sensitivity distributions, and different choices for error distributions or weights can result in significantly different regions of high sensitivity. Thus, in order to design effective sampling networks, the error form and weights must be carefully considered. For the Henry problem, permeability and freshwater inflow can be estimated with low estimation variance from only pressure or only

Searching for Politics with Henry Giroux: Through Cultural Studies to Public Pedagogy and the "Terror of Neoliberalism"

ERIC Educational Resources Information Center

Robbins, Christopher G.

2009-01-01

Henry A. Giroux is recognized as one of the fifty most significant thinkers on education in the 20th century. He is also considered a scholar of immense influence in a number of fields internationally, hardly an inconsequential accolade in a century noted for a glut of educational and social thinkers. Yet, its wide-ranging and ever-expanding…

Health assessment for William Dick Lagoons, Honeybrook, Pennsylvania, Region 3. CERCLIS No. PAD980537773. Preliminary report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-09-30

The William Dick Lagoon site consists of three unlined lagoons (approximately 2.5 acres total area) which previously contained over four million gallons of rinse water from cleaning chemical tank trailers. In 1970, two of the lagoons breached and released approximately 300,000 gallons of wastewater into the nearby area and a small tributary. Trichloroethylene, toluene, 4,4-DDE, and polynuclear aromatic hydrocarbons have been reported in the soil on the site. Trichloroethylene was detected in a nearby spring, previously used as a water source by a small number of residents. Potential human exposure pathways include ingestion of contaminated water, dermal exposure to contaminatedmore » water and soil, and inhalation of contaminated dust and organics in the contaminated groundwater. The site is considered to be of potential public health concern because of the risk to human health caused by the possibility of exposure to hazardous substances. However, it does not appear that a human population is currently exposed to site contaminants at levels of health concern.« less

Style and non-style in anatomical illustration: From Renaissance Humanism to Henry Gray.

PubMed

Kemp, Martin

2010-02-01

Style is a familiar category for the analysis of art. It is less so in the history of anatomical illustration. The great Renaissance and Baroque picture books of anatomy illustrated with stylish woodcuts and engravings, such as those by Charles Estienne, Andreas Vesalius and Govard Bidloo, showed figures in dramatic action in keeping with philosophical and theological ideas about human nature. Parallels can be found in paintings of the period, such as those by Titian, Michelangelo and Hans Baldung Grien. The anatomists also claimed to portray the body in an objective manner, and showed themselves as heroes of the discovery of human knowledge. Rembrandt's painting of Dr Nicholas Tulp is the best-known image of the anatomist as hero. The British empirical tradition in the 18th century saw William Cheselden and William Hunter working with techniques of representation that were intended to guarantee detailed realism. The ambition to portray forms life-size led to massive volumes, such as those by Antonio Mascagni. John Bell, the Scottish anatomist, criticized the size and pretensions of the earlier books and argued for a plain style adapted to the needs of teaching and surgery. Henry Gray's famous Anatomy of 1858, illustrated by Henry Vandyke Carter, aspired to a simple descriptive mode of functional representation that avoided stylishness, resulting in a style of its own. Successive editions of Gray progressively saw the replacement of Gray's method and of all his illustrations. The 150th anniversary edition, edited by Susan Standring, radically re-thinks the role of Gray's book within the teaching of medicine.

[Dr. Henry Wigderson--the first neurosurgeon in Eretz-Israel].

PubMed

Feinsod, Moshe

2006-07-01

The vision of Hadassah Medical Organization and the Hebrew University in Jerusalem was to establish a University Hospital where clinical excellence and high academic level will be the hallmark of its departments. More than seventy years ago, guided by this spirit, the leaders of the two institutions attempted to establish a department of neurosurgery, which, at the time in only a few countries, was making its initial steps as an independent discipline. It was only during World War II that Hadassah could bring over a specialist in neurosurgery who worked for nearly three years in the Hadassah Hospital on Mount Scopus. This article describes the way Dr. Henry Wigderson was selected to be the first neurosurgeon in Eretz-Israel, his activities and the incorporation of the idea, in spite of the disappointment caused by his departure, that even at times of distress, neurosurgery is not a luxury but an indispensable part of an forward-looking medical institution.

James Henry Marriott: New Zealand's first professional telescope-maker

NASA Astrophysics Data System (ADS)

Orchiston, Wayne; Romick, Carl; Brown, Pendreigh.

2015-11-01

James Henry Marriott was born in London in 1799 and trained as an optician and scientific instrument- maker. In 1842 he emigrated to New Zealand and in January 1843 settled in the newly-established town of Wellington. He was New Zealand's first professional telescope-maker, but we have only been able to locate one telescope made by him while in New Zealand, a brass 1-draw marine telescope with a 44-mm objective, which was manufactured in 1844. In 2004 this marine telescope was purchased in Hawaii by the second author of this paper. In this paper we provide biographical information about Marriott, describe his 1844 marine telescope and speculate on its provenance. We conclude that although he may have been New Zealand's first professional telescope-maker Marriot actually made very few telescopes or other scientific instruments. As such, rather than being recognised as a pioneer of telescope-making in New Zealand he should be remembered as the founder of New Zealand theatre.

Rotational spectroscopy of cold and trapped molecular ions in the Lamb-Dicke regime

NASA Astrophysics Data System (ADS)

Alighanbari, S.; Hansen, M. G.; Korobov, V. I.; Schiller, S.

2018-06-01

Sympathetic cooling of trapped ions has been established as a powerful technique for the manipulation of non-laser-coolable ions1-4. For molecular ions, it promises vastly enhanced spectroscopic resolution and accuracy. However, this potential remains untapped so far, with the best resolution achieved being not better than 5 × 10-8 fractionally, due to residual Doppler broadening being present in ion clusters even at the lowest achievable translational temperatures5. Here we introduce a general and accessible approach that enables Doppler-free rotational spectroscopy. It makes use of the strong radial spatial confinement of molecular ions when trapped and crystallized in a linear quadrupole trap, providing the Lamb-Dicke regime for rotational transitions. We achieve a linewidth of 1 × 10-9 fractionally and 1.3 kHz absolute, an improvement of ≃50-fold over the previous highest resolution in rotational spectroscopy. As an application, we demonstrate the most precise test of ab initio molecular theory and the most accurate (1.3 × 10-9) determination of the proton mass using molecular spectroscopy. The results represent the long overdue extension of Doppler-free microwave spectroscopy of laser-cooled atomic ion clusters6 to higher spectroscopy frequencies and to molecules. This approach enables a wide range of high-accuracy measurements on molecules, both on rotational and, as we project, vibrational transitions.

"Extraordinary Understandings" of Composition at the University of Chicago: Frederick Champion Ward, Kenneth Burke, and Henry W. Sams

ERIC Educational Resources Information Center

Beasley, James P.

2007-01-01

While Richard Weaver, R. S. Crane, Richard McKeon, and Robert Streeter have been most identified with rhetoric at the University of Chicago and its institutional return in the 1950s, the archival record demonstrates that Frederick Champion Ward, dean of the undergraduate "College" from 1947 to 1954, and Henry W. Sams, director of English…

A Vision for the Future: Henry G. Bennett Memorial Library, Southeastern Oklahoma State University Strategic Plan, 2002-2007.

ERIC Educational Resources Information Center

Davis, Dorothy

This document presents the five-year strategic plan developed by the library director, staff, and the Library Committee for the Henry G. Bennett Memorial Library, Southeastern Oklahoma State University. The goal of this plan is to provide a framework that the library can use to focus energy and resources in fulfilling the mission of the library…

Plastic (wire-combed) grooving of a slip-formed concrete runway overlay at Patrick Henry Airport: An initial evaluation

NASA Technical Reports Server (NTRS)

Marlin, E. C.; Horne, W. B.

1977-01-01

A wire-comb technique is described for transversely grooving the surface of a freshly laid (plastic state) slip-formed concrete overlay installed at Patrick Henry Airport. This method of surface texturing yields better water drainage and pavement skid resistance than that obtained with an older conventional burlap drag concrete surface treatment installed on an adjacent portion of the runway.

40 CFR Appendix Vi to Part 265 - Compounds With Henry's Law Constant Less Than 0.1 Y/X

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Compounds With Henry's Law Constant Less Than 0.1 Y/X VI Appendix VI to Part 265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Law Constant Less Than 0.1 Y/X Compound name CAS No. Acetaldol 107-89-1 Acetamide 60-35-5 2...

40 CFR Appendix Vi to Part 265 - Compounds With Henry's Law Constant Less Than 0.1 Y/X

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Compounds With Henry's Law Constant Less Than 0.1 Y/X VI Appendix VI to Part 265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Law Constant Less Than 0.1 Y/X Compound name CAS No. Acetaldol 107-89-1 Acetamide 60-35-5 2...

40 CFR Appendix Vi to Part 265 - Compounds With Henry's Law Constant Less Than 0.1 Y/X

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Compounds With Henry's Law Constant Less Than 0.1 Y/X VI Appendix VI to Part 265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Law Constant Less Than 0.1 Y/X Compound name CAS No. Acetaldol 107-89-1 Acetamide 60-35-5 2...

40 CFR Appendix Vi to Part 265 - Compounds With Henry's Law Constant Less Than 0.1 Y/X

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Compounds With Henry's Law Constant Less Than 0.1 Y/X VI Appendix VI to Part 265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Law Constant Less Than 0.1 Y/X Compound name CAS No. Acetaldol 107-89-1 Acetamide 60-35-5 2...

40 CFR Appendix Vi to Part 265 - Compounds With Henry's Law Constant Less Than 0.1 Y/X

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Compounds With Henry's Law Constant Less Than 0.1 Y/X VI Appendix VI to Part 265 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Law Constant Less Than 0.1 Y/X Compound name CAS No. Acetaldol 107-89-1 Acetamide 60-35-5 2...

2006 Henry f. Smyth jr. Award lecture historical review--employer responsibility for workplace health and safety.

PubMed

Henshaw, John L

2007-02-01

The Academy of Industrial Hygiene established the Henry F. Smyth Jr. Award in 1981. The Award is presented to that individual who has recognized the needs of the industrial hygiene profession and has made major contributions to fulfill those needs, thereby contributing to the improvement of the public welfare. This year's Award was presented to John L. Henshaw, CIH, at the 2006 Professional Conference on Industrial Hygiene (PCIH) in San Jose, California.

Cecilia Payne-Gaposchkin, Henry Norris Russell Lecture: Fifty Years of Novae

NASA Astrophysics Data System (ADS)

Burbidge, E. M.

1999-05-01

It is easy to pick out my most memorable meeting of the AAS: the 149th meeting held in January, 1977, and hosted by the University of Hawaii, in Honolulu, HI. It was the meeting at which two traditions of the Society were broken, and we moved into the era of equal opportunity for women astronomers. Cecilia Payne-Gaposchkin received the highest award of the AAS: the Henry Norris Russell Lectureship. This award had never before been available to women, otherwise Cecilia would, years earlier, have been honored for the many achievements in her lifetime of renowned astronomical research. And I, the first woman to be elected President of the AAS, had the honor of presenting the illuminated scroll to Cecilia, and of introducing her on the platform where she delivered the Henry Norris Russell Prize Lecture, entitled ``Fifty Years of Novae"(1) . Cecilia opened by comparing the experience of young and old scientists in achieving exciting results from their research, and then led us through the history of the discoveries of and about some famous novae. She described the physical picture that emerged from studies of their light curves, their spectra, and the discovery of their binary nature. Three important tables were included, listing data on cataclysmic binaries (dwarf novae) and their link to the nova phenomenon in general. She recalled that she and Sergei Gaposchkin had hesitated between the names catastrophic and cataclysmic for the dwarf novae, and decided on the latter, from the dictionary definitions of those two terms: ``a cataclysm is a great and general flood" while a catastrophe ``is a final event". The nova phenomenon is recurrent, as are the dwarf novae, and both involve an outpouring of a flood of energy. She concluded by describing her 50 years' experience with novae as presenting ``the contemporary portrait of a nova", rather than a final picture, and by forecasting that the next 50 years of discovering and studying novae will be as full of surprises as the

Performance of an alkalophilic and halotolerant laccase from gamma-proteobacterium JB in the presence of industrial pollutants.

PubMed

Singh, Gursharan; Sharma, Prince; Capalash, Neena

2009-08-01

An alkalophilic and halotolerant laccase from gamma-proteobacterium JB catalyzed in high concentrations of organic solvents and various salts. The enzyme retained 80-100% activity in 10% concentration of dimethylsulfoxide (DMSO), ethanol, acetone or methanol; 100, 85 and 50% activity in 20 mM MgCl(2), 5.0 mM MnCl(2) and 0.1 mM CuCl(2); 140, 120 and 110% activity in 5.0 mM MnSO(4), 10 mM MgSO(4) and 1mM CaSO(4), respectively. Sodium halides inhibited the enzyme in the order: F(-)> Br(-)> I(-)> Cl(-). In 0.5 M NaCl, pH 6.0, laccase was approximately 60% active. Decolorization of indigo carmine by laccase at pH 9.0 was not inhibited even in the presence of 0.5 M NaCl. Release of chromophoric, reducing and hydrophobic compounds during biobleaching of straw rich-soda pulp by laccase was not inhibited when the enzyme was applied in the presence of 1 M NaCl at pH 8.0. Laccase retained 50% residual activity even when incubated with 5% calcium hypochlorite for 30 min.

Style and non-style in anatomical illustration: From Renaissance Humanism to Henry Gray

PubMed Central

Kemp, Martin

2010-01-01

Style is a familiar category for the analysis of art. It is less so in the history of anatomical illustration. The great Renaissance and Baroque picture books of anatomy illustrated with stylish woodcuts and engravings, such as those by Charles Estienne, Andreas Vesalius and Govard Bidloo, showed figures in dramatic action in keeping with philosophical and theological ideas about human nature. Parallels can be found in paintings of the period, such as those by Titian, Michelangelo and Hans Baldung Grien. The anatomists also claimed to portray the body in an objective manner, and showed themselves as heroes of the discovery of human knowledge. Rembrandt’s painting of Dr Nicholas Tulp is the best-known image of the anatomist as hero. The British empirical tradition in the 18th century saw William Cheselden and William Hunter working with techniques of representation that were intended to guarantee detailed realism. The ambition to portray forms life-size led to massive volumes, such as those by Antonio Mascagni. John Bell, the Scottish anatomist, criticized the size and pretensions of the earlier books and argued for a plain style adapted to the needs of teaching and surgery. Henry Gray’s famous Anatomy of 1858, illustrated by Henry Vandyke Carter, aspired to a simple descriptive mode of functional representation that avoided stylishness, resulting in a style of its own. Successive editions of Gray progressively saw the replacement of Gray’s method and of all his illustrations. The 150th anniversary edition, edited by Susan Standring, radically re-thinks the role of Gray’s book within the teaching of medicine. PMID:20447244

Design of a gap tunable flux qubit with FastHenry

NASA Astrophysics Data System (ADS)

Akhtar, Naheed; Zheng, Yarui; Nazir, Mudassar; Wu, Yulin; Deng, Hui; Zheng, Dongning; Zhu, Xiaobo

2016-12-01

In the preparations of superconducting qubits, circuit design is a vital process because the parameters and layout of the circuit not only determine the way we address the qubits, but also strongly affect the qubit coherence properties. One of the most important circuit parameters, which needs to be carefully designed, is the mutual inductance among different parts of a superconducting circuit. In this paper we demonstrate how to design a gap-tunable flux qubit by layout design and inductance extraction using a fast field solver FastHenry. The energy spectrum of the gap-tunable flux qubit shows that the measured parameters are close to the design values. Project supported by the National Natural Science Foundation of China (Grant Nos. 11374344, 11404386, and 91321208), the National Basic Research Program of China (Grant No. 2014CB921401), and the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDB07010300).

On the "Critique of Everyday Life" to "Metaphilosophy": Henri Lefebvre's Philosophical-Political Legacy of the Cultural Revolution

ERIC Educational Resources Information Center

Sünker, Heinz

2014-01-01

Henri Lefebvre (1901-91), philosopher and sociologist, is, together with Theodor W. Adorno, Max Horkheimer, Walter Benjamin and Ernst Bloch, one of the most relevant representatives of the first generation in Western Marxism. His engagement with Marxism led him to analyse everyday life in post-war France in order to decipher the possibilities of,…

[Sauveur-Henri-Victor Bouvier (1799-1877): orthopaedist, surgeon and promoter of physical education].

PubMed

Monet, Jacques; Quin, Grégory

2013-01-01

This article establishes the biography of a little known physician of the 19th century., whose commitment with orthopaedics and formulation of medical gymnastics was important: the surgeon-orthopaedist Sauveur-Henri-Victor Bouvier. Several constitutive processes of the medical field of the 19th century are analysed: specialization (around orthopaedics), professionalization and development of various therapeutic and hygienic methods (among them medical gymnastics). Bouvier's biography is particularly instructive and sheds new light on these different processes, as well as on the institutionalization of orthopaedics from the 1820's up to the 1870's, at the intersection between medical and educative fields, between hospital, medical faculty and teaching of gymnastics.

[Charles-Henri Fialon (1846-1933). Creator of the historical museum of the faculty of pharmacy of Paris].

PubMed

Bzoura, Elie; Flahaut, Jean

2004-01-01

Charles-Henri Fialon stopped his pharmaceutical activities in 1892 and he devoted his time to artistic and historic works. He achieved an important collection of pharmaceutical pots and objects which he gave to the school of Pharmacy of Paris. These gifts were collected in a room named "Musée Fialon ". This museum was enlarged twice and presently is in the "Guillaume Valette" gallery. His content is described in this paper.

Henry Beecher's Contributions to the Ethics of Clinical Research.

PubMed

Veatch, Robert M

2016-01-01

In the 1950s and '60s, Henry Beecher pioneered the discussion of the ethics of clinical research, leading eventually to the publication of the famous New England Journal of Medicine article summarizing 22 research studies that Beecher suggests were unethical. Those studies generally showed a pattern of posing serious risks to subjects without anticipated proportional benefit. Beecher famously claimed that the problem was not that researchers were malicious or evil; rather, he claimed the problem was they manifested thoughtlessness or carelessness. He called for more rigorous self-scrutiny rather than public review.This article argues that Beecher's reliance on conscientious investigators is problematic. In particular, it focuses on benefits and harms to the exclusion of other moral criteria. However, both research subjects and public regulators are also concerned about autonomy and the consent requirement, confidentiality, and fairness in subject selection and research design. The movement in the 1970s toward more public scrutiny was critical, even though Beecher was right in holding that it was not "vicious disregard for subject welfare" that explained unethical protocols.

Sapflow of hybrid poplar (Populus nigra L. x P. maximowiczii A. Henry 'NM6') during phytoremediation of landfill leachate

Treesearch

Ronald S., Jr. Zalesny; Adam H. Wiese; Edmund O. Bauer; Don E. Riemenschneider

2006-01-01

Poplars are ideal for phytoremediation because of their high water usage, fast growth, and deep root systems. We measured in 2002 and 2003 the sapflow of hybrid poplars (Populus nigra L. x P. maximowiczii A. Henry 'NM6') planted in 1999 for phytoremediation of a landfill in Rhinelander, WI, USA (45.6?N, 89.4?W).

Modeling water quality effects of structural and operational changes to Scoggins Dam and Henry Hagg Lake, Oregon

USGS Publications Warehouse

Sullivan, Annett B.; Rounds, Stewart A.

2006-01-01

To meet water quality targets and the municipal and industrial water needs of a growing population in the Tualatin River Basin in northwestern Oregon, an expansion of Henry Hagg Lake is under consideration. Hagg Lake is the basin's primary storage reservoir and provides water during western Oregon's typically dry summers. Potential modifications include raising the dam height by 6.1 meters (20 feet), 7.6 meters (25 feet), or 12.2 meters (40 feet); installing additional outlets (possibly including a selective withdrawal tower); and adding additional inflows to provide greater reliability of filling the enlarged reservoir. One method of providing additional inflows is to route water from the upper Tualatin River through a tunnel and into Sain Creek, a tributary to the lake. Another option is to pump water from the Tualatin River (downstream of the lake) uphill and into the reservoir during the winter--the 'pump-back' option. A calibrated CE-QUAL-W2 model of Henry Hagg Lake's hydrodynamics, temperature, and water quality was used to examine the effect of these proposed changes on water quality in the lake and downstream. Most model scenarios were run with the calibrated model for 2002, a typical water year; a few scenarios were run for 2001, a drought year. More...

Fugitive from Labor Cases: Henry Garnett (1850) and Moses Honner (1860). The Constitution Community: Civil War and Reconstruction (1850-1870).

ERIC Educational Resources Information Center

Lawlor, John M., Jr.

The cases of Henry Garnett and Moses Honner bookend the 1850s, a decade of intensifying political crisis that was deeply connected to the institution of slavery. In both court actions, which were tried in the Third Circuit Court, Eastern District, Philadelphia, Pennsylvania, the defendants were charged with being "fugitives from labor."…

Samuel Hartlib on the death of Descartes: a rediscovered letter to Henry More

PubMed Central

Penman, Leigh T. I.

2015-01-01

This paper discloses the content of a previously overlooked epistle by the Anglo-Prussian intelligencer Samuel Hartlib to Henry More concerning the death of René Descartes. After a discussion situating the letter within the sequence of the More–Hartlib correspondence, an analysis of the rhetorical structure of the epistle is offered, followed by a brief assessment of Hartlib's attitude towards Descartes, and the identification of his source concerning the news of the philosopher's death. An account of the transmission of the letter via a nineteenth-century periodical is also provided. The text of Hartlib's letter and an overlooked passage of Hartlib's diary concerning Descartes's death, which draws on the content of the More letter, are presented as appendixes.

Why Henry III of Navarre’s Hair Probably did not Turn White Overnight

PubMed Central

Navarini, Alexander A; Trüeb, Ralph M

2010-01-01

Although a rare event, sudden whitening of hair (canities subita) has reportedly affected a number of well-known historical figures, usually in relation to dramatic events in their lives. Although early accounts are substantiated by more recent case reports in scientific literature, we suspect that the phenomenon is not only used as a literary means in fiction, with the aim of dramatizing, but probably also in historical accounts. For this purpose, we examine the case history of Henry III of Navarre who allegedly turned white on the evening of the Saint Bartholomew’s day massacre, and challenge this claim, due to inconsistencies in his biography, with the current pathophysiological understanding of canities subita. PMID:21188015

Measurement of Henry's Law Constants Using Internal Standards: A Quantitative GC Experiment for the Instrumental Analysis or Environmental Chemistry Laboratory

ERIC Educational Resources Information Center

Ji, Chang; Boisvert, Susanne M.; Arida, Ann-Marie C.; Day, Shannon E.

2008-01-01

An internal standard method applicable to undergraduate instrumental analysis or environmental chemistry laboratory has been designed and tested to determine the Henry's law constants for a series of alkyl nitriles. In this method, a mixture of the analytes and an internal standard is prepared and used to make a standard solution (organic solvent)…

Perturbation theory in the catalytic rate constant of the Henri-Michaelis-Menten enzymatic reaction.

PubMed

Bakalis, Evangelos; Kosmas, Marios; Papamichael, Emmanouel M

2012-11-01

The Henry-Michaelis-Menten (HMM) mechanism of enzymatic reaction is studied by means of perturbation theory in the reaction rate constant k (2) of product formation. We present analytical solutions that provide the concentrations of the enzyme (E), the substrate (S), as well as those of the enzyme-substrate complex (C), and the product (P) as functions of time. For k (2) small compared to k (-1), we properly describe the entire enzymatic activity from the beginning of the reaction up to longer times without imposing extra conditions on the initial concentrations E ( o ) and S ( o ), which can be comparable or much different.

Analytical Phase Equilibrium Function for Mixtures Obeying Raoult's and Henry's Laws

NASA Astrophysics Data System (ADS)

Hayes, Robert

When a mixture of two substances exists in both the liquid and gas phase at equilibrium, Raoults and Henry's laws (ideal solution and ideal dilute solution approximations) can be used to estimate the gas and liquid mole fractions at the extremes of either very little solute or solvent. By assuming that a cubic polynomial can reasonably approximate the intermediate values to these extremes as a function of mole fraction, the cubic polynomial is solved and presented. A closed form equation approximating the pressure dependence on mole fraction of the constituents is thereby obtained. As a first approximation, this is a very simple and potentially useful means to estimate gas and liquid mole fractions of equilibrium mixtures. Mixtures with an azeotrope require additional attention if this type of approach is to be utilized. This work supported in part by federal Grant NRC-HQ-84-14-G-0059.

Enhanced production of alkaline thermostable keratinolytic protease from calcium alginate immobilized cells of thermoalkalophilic Bacillus halodurans JB 99 exhibiting dehairing activity.

PubMed

Shrinivas, Dengeti; Kumar, Raghwendra; Naik, G R

2012-01-01

The thermoalkalophilic Bacillus halodurans JB 99 cells known for production of novel thermostable alkaline keratinolytic protease were immobilized in calcium alginate matrix. Batch and repeated batch cultivation using calcium alginate immobilized cells were studied for alkaline protease production in submerged fermentation. Immobilized cells with 2.5% alginate and 350 beads/flask of initial cell loading showed enhanced production of alkaline protease by 23.2% (5,275 ± 39.4 U/ml) as compared to free cells (4,280 ± 35.4 U/ml) after 24 h. In the semicontinuous mode of cultivation, immobilized cells under optimized conditions produced an appreciable level of alkaline protease in up to nine cycles and reached a maximal value of 5,975 U/ml after the seventh cycle. The enzyme produced from immobilized cells efficiently degraded chicken feathers in the presence of a reducing agent which can help the poultry industry in the management of keratin-rich waste and obtaining value-added products.

Henri Poincaré and the principle of relativity

NASA Astrophysics Data System (ADS)

Messager, Valérie; Gilmore, Robert; Letellier, Christophe

2012-09-01

Often considered as the last 'encyclopedist', Henri Poincaré died one hundred years ago. If he was a prominent man in 1900 French Society, his heritage is not so clearly recognised, particularly in France. Among his too often misunderstood works is his contribution to the theory of relativity, mainly because it is almost never presented within Poincaré's general approach to science, including his philosophical writings. Our aim is therefore to provide an historical account of the main steps (experimental as well as theoretical) which led Poincaré to contribute to the theory of relativity. Starting from the optical experiments which led to the inconsistency of the classical (Galilean) composition law for velocities to explain light propagation, we introduce the FitzGerald and Lorentz contraction which was viewed as the 'sole hypothesis' to explain the Michelson and Morley experiment. We then show that Poincaré's contribution starts with a discussion of the principles governing the mechanics and was built step by step up to express in all its generality the principle of relativity. Poincaré thus showed the invariance of the Maxwell equations under the Lorentz transformation. In doing so, he also discovered the right composition law for velocities. Poincaré's approach to philosophy is detailed to help the reader to understand what a theory meant to him.

Henry Adams’s Life of George Cabot Lodge: A Portrait of the Artist as an Alienated Man

DTIC Science & Technology

1994-07-20

literary tradition, especially as had been handed down from Adams’s Puritan forebears. My aim is to present the most complete critical study of this...several critics have pointed to this book as evidence of Adams’s diminished talents--when a careful study of the book in fact demonstrates otherwise...critical studies have given more than cursory attention to the Life of Lodge: J. C. Levenson, The Mind and Art of Henry Adams (1957); George Hochfield

Surface-water/ground-water interaction along reaches of the Snake River and Henrys Fork, Idaho

USGS Publications Warehouse

Hortness, Jon E.; Vidmar, Peter

2005-01-01

Declining water levels in the eastern Snake River Plain aquifer and decreases in spring discharges from the aquifer to the Snake River have spurred studies to improve understanding of the surface-water/ground-water interaction on the plain. This study was done to estimate streamflow gains and losses along specific reaches of the Snake River and Henrys Fork and to compare changes in gain and loss estimates to changes in ground-water levels over time. Data collected during this study will be used to enhance the conceptual model of the hydrologic system and to refine computer models of ground-water flow and surface-water/ground-water interactions. Estimates of streamflow gains and losses along specific subreaches of the Snake River and Henrys Fork, based on the results of five seepage studies completed during 2001?02, varied greatly across the study area, ranging from a loss estimate of 606 ft3/s in a subreach of the upper Snake River near Heise to a gain estimate of 3,450 ft3/s in a subreach of the Snake River that includes Thousand Springs. Some variations over time also were apparent in specific subreaches. Surface spring flow accounted for much of the inflow to subreaches having large gain estimates. Several subreaches alternately gained and lost streamflow during the study. Changes in estimates of streamflow gains and losses along some of the subreaches were compared with changes in water levels, measured at three different times during 2001?02, in adjacent wells. In some instances, a strong relation between changes in estimates of gains or losses and changes in ground-water levels was apparent.

Thomas Henry Osler (1875-1936): a descendant of Sir William Osler's great-uncle and the founder of a South African medical dynasty.

PubMed

Myers, Edward D

2009-08-01

Sir William Osler's great-uncle Benjamin emigrated from England to South Africa with his wife and children in 1820. From Benjamin's son, Stephen, descended a large family of Oslers including at least seven doctors and dentists. This paper describes the lives and careers of Thomas Henry, and his medical and dental descendants.

When is an imine not an imine? Unusual reactivity of a series of Cu(II) imine-pyridine complexes and their exploitation for the Henry reaction.

PubMed

Cooper, Christine J; Jones, Matthew D; Brayshaw, Simon K; Sonnex, Benjamin; Russell, Mark L; Mahon, Mary F; Allan, David R

2011-04-14

In this paper we report the synthesis and solid-state structures for a series of pyridine based Cu(II) complexes and preliminary data for the asymmetric Henry reaction. Interestingly, the solid-state structures indicate the incorporation of an alcohol into one of the imine groups of the ligand, forming a rare α-amino ether group. The complexes have been studied via single crystal X-ray diffraction, EPR spectroscopy and mass spectrometry. Intriguingly, it has been observed that the alcohol only adds to one of the imine moieties. Density functional theory (DFT) calculations have also been employed to rationalise the observed structures. The Cu(II) complexes have been tested in the asymmetric Henry reaction (benzaldehyde + nitromethane or nitroethane) with ee's up to 84% being achieved as well as high conversions and modest diastereoselectivities. © The Royal Society of Chemistry 2011

Artist as Educator? Assessing the Pedagogic Role of Folly in the Early Work of the Anglo-Swiss Artist Henry Fuseli (1741-1825)

ERIC Educational Resources Information Center

Smith, Hester Camilla

2010-01-01

This article examines a group of five ink, pen and wash drawings produced by the Anglo-Swiss artist Henry Fuseli in the mid-eighteenth century in Zurich. The drawings were produced for a "Narrenbuch" (Book of Fools) uniting visual images of folly with humorous slogans. The drawings are significant in that they imitate sixteenth-century…

The enigmatic figure of Dr Henry Maudsley (1835-1918).

PubMed

Pantelidou, Maria; Demetriades, Andreas K

2014-08-01

In spite of his contribution to psychiatry in 19th century Britain, Henry Maudsley remains a mysterious figure, a man mostly known for his donation to the London County Council for the building of the Maudsley Hospital and for The Maudsley Annual Lecture created in honour of his benevolence. Besides Sir Aubrey Lewis' article in 1951 and Michael Collie's attempt in 1988 to construct a biographical study on Maudsley, there does not seem to be any current endeavour to tell the story of his life, whereas Trevor Turner's contribution to the 2004 Oxford Dictionary of National Biography gives a somewhat scathing but unattributed account of Maudsley's personality. This essay attempts to explore his contributions to the Medico-Psychological Association (MPA), the current Royal College of Psychiatrists, his editorship of the Journal of Mental Health (currently named the British Journal of Psychiatry), his literary contributions and his vision for a psychiatric hospital. This essay is an attempt to demystify his figure and to explore some of the rumours and criticisms surrounding his name and the reasons why so little has been written about him. It is also a venture to unravel his complex personality and his intricate philosophy. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

HENRY H. CHEEK AND TRANSFORMISM: NEW LIGHT ON CHARLES DARWIN'S EDINBURGH BACKGROUND.

PubMed

Jenkins, Bill

2015-06-20

Evidence for the transformist ideas espoused by Henry H. Cheek (1807-33), a contemporary of Charles Darwin's at the University of Edinburgh, sheds new light on the intellectual environment of Edinburgh in the late 1820s and early 1830s. Cheek was the author of several papers dealing with the transmutation of species influenced by the theories of Etienne Geoffroy Saint-Hilaire (1772-1844), Jean-Baptiste Lamarck (1744-1829) and the Comte de Buffon (1707-88). Some of these were read to student societies, others appeared in the Edinburgh Journal of Natural and Geographical Science, which Cheek edited between 1829 and 1831. His writings give us a valuable window onto some of the transformist theories that were circulating among Darwin's fellow medical students in the late 1820s, to which Darwin would have been exposed during his time in Edinburgh, and for which little other concrete evidence survives.

Henry Solomon Wellcome: A philanthropist and a pioneer sponsor of medical research in the Sudan

PubMed Central

2013-01-01

Henry Solomon Wellcome, the famous drug manufacturer had a fascinating association with the Sudan. Besides supporting tropical medicine research in this country, he established an extensive project in the Sudan that aimed at combining archeological excavations, philanthropy and social reform. This article is an archives-based account on this side of Wellcome’s association with the Sudan. The article starts with Wellcome’s early years in the American Midwest and the evolution of his career and his rise as a world-renowned drug manufacturer. After the battle of Omdurman, Wellcome visited Sudan in 1900 – 1901 where he offered to support the establishment of the research laboratories which later came to be known as the Wellcome Tropical Research Laboratories in Khartoum. He then became directly involved in the planning and running of extensive archeological excavations in the central Sudan. This project served as a field in which Wellcome found an outlet for his philanthropy. More than 4000 labourers were employed in Jebel Moya. Professional archeologists and anatomists were recruited by Wellcome to supervise the work, and all the requirements in terms of equipment were catered for. Wellcome devised a Savings Bank System whereby part of the earnings of each labourer were saved to him till the end of the season. He also introduced one of his innovations: aerial photography using box kite which was used for the first time in archeology. Wellcome made it a rule that no applicant should be turned away. The Camp Commandant had to find suitable work for each applicant, including the handicapped who were assigned to appropriate jobs like mending baskets or cutting grass for building huts. Wellcome’s welfare work had a significant impact on the local inhabitants of Jebel Moya. Henry Solomon Wellcome, 1906. Oil painting by Hugh Goldwin Riviere. Credit: Wellcome Library PMID:27493379

About Time. Physics, Philosophy and the Battle Between Albert Einstein and Henri Bergson

NASA Astrophysics Data System (ADS)

Frank, Adam

The historical relationship between physics and philosophy has had many famous high and low points. The two function best when both can challenge and support each other. In this talk I explore the famous debate between Albert Einstein and Henri Bergson over the nature of time. While history rightly judged Einstein to have won the debate in terms of relativity, there were deeper aspects of Bergsons critique that remain unappreciated. We will explore the different ways philosophy approaches the issue of time. In particular, we will look at the Continental Schools\\x9D, such as Phenomenology, which brings a unique perspective to the debate lying outside the traditional approach of physicists. From this perspective questions related to the act of being an observer, its essential subjective nature and the proper context of physics can be explored.

Mapping Henry: Synchrotron-sourced X-ray fluorescence mapping and ultra-high-definition scanning of an early Tudor portrait of Henry VIII

NASA Astrophysics Data System (ADS)

Dredge, Paula; Ives, Simon; Howard, Daryl L.; Spiers, Kathryn M.; Yip, Andrew; Kenderdine, Sarah

2015-11-01

A portrait of Henry VIII on oak panel c. 1535 has recently undergone technical examination to inform questions regarding authorship and the painting's relationship to a group of similar works in the collections of the National Portrait Gallery, London, and the Society of Antiquaries. Due to previous conservation treatments of the painting, the conventional transmission X-radiograph image was difficult to interpret. As a result, the painting underwent high-definition X-ray fluorescence (XRF) elemental mapping on the X-ray fluorescence microscopy beamline of the Australian Synchrotron. Scans were conducted at 12.6 and 18.5 keV, below and above the lead (Pb) L edges, respectively. Typical scan parameters were 120 μm pixel size at 7 ms dwell time, with the largest scan covering an area 545 × 287 mm2 collected in 23 h (10.8 MP). XRF mapping of the panel has guided the conservation treatment of the painting and the revelation of previously obscured features. It has also provided insight into the process of making of the painting. The informative and detailed elemental maps, alongside ultra-high-definition scans of the painting undertaken before and after varnish and over-paint removal, have assisted in comparison of the finely painted details with the London paintings. The resolution offered by the combination of imaging techniques identifies pigment distribution at an extremely fine scale, enabling a new understanding of the artist's paint application.

Henry H. Cheek and transformism: new light on Charles Darwin's Edinburgh background

PubMed Central

Jenkins, Bill

2015-01-01

Evidence for the transformist ideas espoused by Henry H. Cheek (1807–33), a contemporary of Charles Darwin's at the University of Edinburgh, sheds new light on the intellectual environment of Edinburgh in the late 1820s and early 1830s. Cheek was the author of several papers dealing with the transmutation of species influenced by the theories of Étienne Geoffroy Saint-Hilaire (1772–1844), Jean-Baptiste Lamarck (1744–1829) and the Comte de Buffon (1707–88). Some of these were read to student societies, others appeared in the Edinburgh Journal of Natural and Geographical Science, which Cheek edited between 1829 and 1831. His writings give us a valuable window onto some of the transformist theories that were circulating among Darwin's fellow medical students in the late 1820s, to which Darwin would have been exposed during his time in Edinburgh, and for which little other concrete evidence survives. PMID:26665300

Enantioselective addition of nitromethane to 2-acylpyridine N-oxides. Expanding the generation of quaternary stereocenters with the Henry reaction.

PubMed

Holmquist, Melireth; Blay, Gonzalo; Muñoz, M Carmen; Pedro, José R

2014-02-21

The direct asymmetric Henry reaction with prochiral ketones, leading to tertiary nitroaldols, is an elusive reaction so far limited to a reduced number of reactive substrates such as trifluoromethyl ketones or α-keto carbonyl compounds. Expanding the scope of this important reaction, the direct asymmetric addition of nitromethane to 2-acylpyridine N-oxides catalyzed by a BOX-Cu(II) complex to give the corresponding pyridine-derived tertiary nitroaldols having a quaternary stereogenic center with variable yields and good enantioselectivity, is described.

Diversity-oriented asymmetric catalysis (DOAC): stereochemically divergent synthesis of thiochromanes using an imidazoline-aminophenol-nickel-catalyzed Michael/Henry reaction.

PubMed

Arai, Takayoshi; Yamamoto, Yushi

2014-03-21

The (S,S)-diphenylethylenediamine-derived imidazoline-aminophenol-Ni complex catalyzed tandem asymmetric Michael/Henry reaction of 2-mercaptobenzaldehydes with β-nitrostyrenes to give the corresponding (2S,3R,4R)-2-aryl-3-nitrothiochroman-4-ols in up to 99% diastereoselectivity with 95% ee was demonstrated in diversity-oriented asymmetric catalysis. Reduction of the nitro group of the chiral thiochromanes gave a new series of (2S,3R,4R)-3-amino-2-arylthiochroman-4-ols with retention of the strereoselectivity.

The Works of Henry Moseley, 1887-1915

NASA Astrophysics Data System (ADS)

Scerri, Eric

2013-04-01

In 1913 Henry Moseley, an unknown young English physicist published an article in the Philosophical Magazine under the title of ``The High Frequency Spectra of the Elements.'' The 10-page article was to have far reaching implications in both chemistry and physics and helped to resolve a major conundrum in the periodic table of the elements. The talk will briefly examine the life and work of Moseley who died tragically while fighting in the trenches of World War I in 1915. The build-up to the discovery of atomic number took several different avenues including contributions from Rutherford and Barkla. However the more direct motivation for Moseley's work, as he readily acknowledged, were the articles of an unknown Dutch econometrician Anton Van den Broek who attempted to improve on Mendeleev's periodic table. Moseley began as a student of Rutherford at Manchester and took a keen interest in the development of research using X-rays following the work of Roentgen, von Laue and Bragg. Although Rutherford was at first reluctant to enter this new field he soon yielded to young Moseley's request and sent him to Leeds for brief training with Bragg. On returning to Manchester, Moseley devised an ingenious apparatus in which a set of metal samples could be rotated so as to become the target for a beam of electrons in order to measure the frequencies of the emitted K X-rays. The first set of such experiments used nine successive elements in the periodic table, from titanium to zinc. Moseley's now immense fame rests with the results of this study as well as a subsequent one which extended the study into a further 30 elements, in addition to the use that his method was put to by himself as well as subsequent chemists and physicists.

Henry Ingersoll Bowditch and Oliver Wendell Holmes: stethoscopists and reformers.

PubMed

Felts, John H

2002-01-01

Two Bostonians, Henry Ingersoll Bowditch (1808-1892) and Oliver Wendell Holmes (1809-1894), went to Paris for advanced medical training and came home ardent disciples of Pierre Charles Alexandre Louis, leader of the French school that derived its eminence from expert auscultation and careful correlation of bedside and autopsy findings. Both Bowditch and Holmes became leaders in 19th-century American medicine. Bowditch, a successful practitioner and prolific medical writer, wrote the first important American text on physical examination and became our first specialist in pulmonary disease. He pioneered in the public health movement, was a charter member and later president of the American Medical Association, and was an abolitionist and an advocate for equal rights for women in medicine. Holmes left practice to become a medical educator. As Dean of Harvard Medical School, he tried unsuccessfully to admit white women and free black men to the school. Although his greatest fame came as a man of letters, Holmes considered himself first a physician and medical educator, and was justifiably proud of his definitive study, "The Contagiousness of Puerperal Fever" (1843). Today, Bowditch and Holmes are little appreciated as pioneers and reformers, but we remain in debt to them both.

Henry Sigerist and the history of medicine in Latin America: his correspondence with Juan R. Beltran.

PubMed

de Asúa, Miguel

2005-01-01

During the years of World War II, the American Association for the History of Medicine fostered a Pan-American policy aimed at establishing relationships with Latin American historians of medicine. Juan R. Beltrán, professor of history of medicine at the University of Buenos Aires, also pursued an energetic program of academic diplomacy. The correspondence between Henry Sigerist and Beltrán makes manifest that by 1941 good channels of communication were established between Baltimore and Buenos Aires, but the friendly links did not last long. The motives for this can be found in the competing aims of the AAHM and Beltrán, and the pattern of international relationships during the war years.

Henry Currey FRIBA (1820-1900): leading Victorian hospital architect, and early exponent of the "pavilion principle".

PubMed

Cook, G C

2002-06-01

The "pavilion plan" for hospital design originated in France in the 18th century and was popularised in England by John Roberton and George Godwin in the mid-19th century; the underlying rationale was that with improved ventilation the mortality rate (at that time exceedingly high) was significantly reduced. Among the enthusiasts for this new style was Florence Nightingale (herself a miasmatist)--who had experienced astronomically high death rates in the hospital at Scutari during the Crimean War (1854-6). One of the leading exponents of this style of hospital architecture was Henry Currey (1820-1900) whose greatest achievement was undoubtedly the design for the new St Thomas's Hospital on the Lambeth Palace Road.

Investigation of Saltwater Intrusion and Recirculation of Seawater for Henry Constant Dispersion and Velocity-Dependent Dispersion Problems and Field-Scale Problem

NASA Astrophysics Data System (ADS)

Motz, L. H.; Kalakan, C.

2013-12-01

Three problems regarding saltwater intrusion, namely the Henry constant dispersion and velocity-dependent dispersion problems and a larger, field-scale velocity-dependent dispersion problem, have been investigated to determine quantitatively how saltwater intrusion and the recirculation of seawater at a coastal boundary are related to the freshwater inflow and the density-driven buoyancy flux. Based on dimensional analysis, saltwater intrusion and the recirculation of seawater are dependent functions of the independent ratio of freshwater advective flux relative to the density-driven vertical buoyancy flux, defined as az (or a for an isotropic aquifer), and the aspect ratio of horizontal and vertical dimensions of the cross-section. For the Henry constant dispersion problem, in which the aquifer is isotropic, saltwater intrusion and recirculation are related to an additional independent dimensionless parameter that is the ratio of the constant dispersion coefficient treated as a scalar quantity, the porosity, and the freshwater advective flux, defined as b. For the Henry velocity-dependent dispersion problem, the ratio b is zero, and saltwater intrusion and recirculation are related to an additional independent dimensionless parameter that is the ratio of the vertical and horizontal dispersivities, or rα = αz/αx. For an anisotropic aquifer, saltwater intrusion and recirculation are also dependent on the ratio of vertical and horizontal hydraulic conductivities, or rK = Kz/Kx. For the field-scale velocity-dependent dispersion problem, saltwater intrusion and recirculation are dependent on the same independent ratios as the Henry velocity-dependent dispersion problem. In the two-dimensional cross-section for all three problems, freshwater inflow occurs at an upgradient boundary, and recirculated seawater outflow occurs at a downgradient coastal boundary. The upgradient boundary is a specified-flux boundary with zero freshwater concentration, and the downgradient

The critical impact of Frantz Fanon and Henri Collomb: race, gender, and personality testing of North and West Africans.

PubMed

Bullard, Alice

2005-01-01

In 2001, the U.S. Surgeon General declared publicly that culture counts in mental health care. This welcome recognition of the role of culture in mental health appears somewhat belated. In 1956, Frantz Fanon and Henri Collomb both presented culturally sensitive studies of the Thematic Apperception Test at the major French-language mental health conference. The contrast between these two studies and between the careers of Fanon and Collomb reveals some of the difficulties in creating cultural and gender sensitivity in psychiatry or psychology. Copyright 2005 Wiley Periodicals, Inc.

Dr Walter Henry Anderson (1870-1937) and the mission hospital at Safed, Palestine.

PubMed

Stokes, Gordon S

2013-02-01

Walter Henry Anderson, a brewer's clerk in Burton-upon-Trent, became a missionary doctor, supported by a society promoting welfare and evangelism in Jewish communities abroad. His family background was rich in pastoral ministry at home and adventure abroad. Arguably, this background played a part in his decision to serve the Jews of Safed. His life in Palestine entailed much enterprise and hardship as he raised a family, fought disease and set up a mission hospital serving not only the Jewish community but persons of all faiths. His years in Palestine, from 1894 to 1915, were times of peace in the Middle East before the turmoil unleashed by the Great War. Jews from the Diaspora were gaining an increasing foothold in Palestine, their 'Promised Land'. Themes of that era - the rise of Zionism, confrontation between Judaism and evangelical Christianity, conflict between immigrant Jew and Palestinian Arab and the remarkable travels of Lawrence of Arabia were interwoven with the lives of Dr Anderson and his family.

Two-relaxation-time lattice Boltzmann method for the anisotropic dispersive Henry problem

NASA Astrophysics Data System (ADS)

Servan-Camas, Borja; Tsai, Frank T.-C.

2010-02-01

This study develops a lattice Boltzmann method (LBM) with a two-relaxation-time collision operator (TRT) to cope with anisotropic heterogeneous hydraulic conductivity and anisotropic velocity-dependent hydrodynamic dispersion in the saltwater intrusion problem. The directional-speed-of-sound technique is further developed to address anisotropic hydraulic conductivity and dispersion tensors. Forcing terms are introduced in the LBM to correct numerical errors that arise during the recovery procedure and to describe the sink/source terms in the flow and transport equations. In order to facilitate the LBM implementation, the forcing terms are combined with the equilibrium distribution functions (EDFs) to create pseudo-EDFs. This study performs linear stability analysis and derives LBM stability domains to solve the anisotropic advection-dispersion equation. The stability domains are used to select the time step at which the lattice Boltzmann method provides stable solutions to the numerical examples. The LBM was implemented for the anisotropic dispersive Henry problem with high ratios of longitudinal to transverse dispersivities, and the results compared well to the solutions in the work of Abarca et al. (2007).

[Charles-Henri Fialon (1846-1933), creator of the Museum of the Faculty of Pharmacy of Paris. His family and professional life].

PubMed

Flahaut, Jean

2004-01-01

Henri Fialon was pharmacist in 1871, and worked in the family apothecary, at Rueil near Paris. At 46 years, he stopped his pharmaceutical activity, and livre quietly, being specially interested by the ancient pharmaceutical pots. He realized a very important collection, which he gave to the French Society of Pharmaceutical History. A museum was installed at the Faculty of Pharmacy of Paris which is presently in the Guillaume Valette Gallery and contains more than 500 pieces.

Anisotropic Bianchi-V dark energy model under the new perspective of accelerated expansion of the universe in Brans-Dicke theory of gravitation

NASA Astrophysics Data System (ADS)

Jaiswal, Rekha; Zia, Rashid

2018-04-01

In this paper, we have proposed a cosmological model, which is consistent with the new findings of `The Supernova Cosmology project' headed by Saul Perlmutter, and the `High-Z Supernova Search team', headed by Brian Schimdt. According to these new findings, the universe is undergoing an expansion with an increasing rate, in contrast to the earlier belief that the rate of expansion is constant or the expansion is slowing down. We have considered spatially homogeneous and anisotropic Bianchi-V dark energy model in Brans-Dicke theory of gravitation. We have taken the scale factor a(t)=k t^α e^{β t} , which results into variable deceleration parameter (DP). The graph of DP shows a transition from positive to negative, which shows that universe has passed through the past decelerated expansion to the current accelerated expansion phase. In this context, we have also calculated and plotted various parameters and observed that these are in good agreement with physical and kinematic properties of the universe and are also consistent with recent observations.

A Cultural Resources Survey of Proposed Excess Tracts within the Harry S. Truman Reservoir Project Henry, St. Clair, and Bates Counties, Missouri

DTIC Science & Technology

1988-03-01

Survey of Proposed Exccess Tracts within the Harry S. Truman Reservoir Projec :. PERFORMING ORG. REPORT NUMSER Henry. St. Clair- and Bates Counties...region surrounding the Harry S. Truman Reservoir have been set out in several prior reports (LeeDecker et al. 1983:34-53; Killer 1983; Roper 1983a:15...construction of the Harry S. Truman Reservoir recorded 38 prehistoric sites, only 3 of which were previously known and reported to the Archaeological

A Laboratory Experiment To Measure Henry's Law Constants of Volatile Organic Compounds with a Bubble Column and a Gas Chromatography Flame Ionization Detector (GC-FID)

ERIC Educational Resources Information Center

Lee, Shan-Hu; Mukherjee, Souptik; Brewer, Brittany; Ryan, Raphael; Yu, Huan; Gangoda, Mahinda

2013-01-01

An undergraduate laboratory experiment is described to measure Henry's law constants of organic compounds using a bubble column and gas chromatography flame ionization detector (GC-FID). This experiment is designed for upper-division undergraduate laboratory courses and can be implemented in conjunction with physical chemistry, analytical…

Effect analysis of quantum chemical descriptors and substituent characteristics on Henry's law constants of polybrominated diphenyl ethers at different temperatures.

PubMed

Long, Jiang; Youli, Qiu; Yu, Li

2017-11-01

Twelve substituent descriptors, 17 quantum chemical descriptors and 1/T were selected to establish a quantitative structure-property relationship (QSPR) model of Henry's law constants for 7 polybrominated diphenyl ethers (PBDEs) at five different temperatures. Then, the lgH of 202 congeners at different temperatures were predicted. The variation rule and regulating mechanism of lgH was studied from the perspectives of both quantum chemical descriptors and substituent characteristics. The R 2 for modeling and testing sets of the final QSPR model are 0.977 and 0.979, respectively, thus indicating good fitness and predictive ability for Henry' law constants of PBDEs at different temperatures. The favorable hydrogen binding sites are the 5,5',6,6'-positions for high substituent congeners and the O atom of the ether bond for low substituent congeners, which affects the interaction between PBDEs and water molecules. lgH is negatively and linearly correlated with 1/T, and the variation trends of lgH with temperature are primarily regulated by individual substituent characteristics, wherein: the more substituents involved, the smaller the lgH. The significant sequence for the main effect of substituent positions is para>meta>ortho, where the ortho-positions are mainly involved in second-order interaction effect (64.01%). Having two substituents in the same ring also provides a significant effect, with 81.36% of second-order interaction effects, particularly where there is an adjacent distribution (55.02%). Copyright © 2017 Elsevier Inc. All rights reserved.

No Evidence against Sketch Reinstatement of Context, Verbal Labels or the Use of Registered Intermediaries for Children with Autism Spectrum Disorder: Response to Henry et al. (2017)

ERIC Educational Resources Information Center

Dando, Coral J.; Ormerod, Thomas C.; Cooper, Penny; Marchant, Ruth; Mattison, Michelle; Milne, Rebecca; Bull, Ray

2018-01-01

Recently, Henry et al. ("J Autism Dev Disord" 8:2348-2362, 2017) found no evidence for the use of Verbal Labels, Sketch Reinstatement of Context and Registered Intermediaries by forensic practitioners when interviewing children with a diagnosis of autism spectrum disorder. We consider their claims, noting the limited ecological validity…

William Henry Bragg, man and scientist, Nobel Laureate and First Professor of Physics, University of Adelaide 1886-1909.

PubMed

Patterson, John; George, Robert

2018-03-01

In London, November 1915, a telegram was received at the home of William Henry Bragg from the secretary of the Academy of Science in Stockholm announcing the award of the Nobel Prize in Physics for "the analysis of crystal structures by means of X-rays". A second similar telegram was addressed to his 25 year old son William Lawrence Bragg (Jenkin, 2008). This article commemorates the centenary of that event and the unveiling of a bust of Sir William Bragg alongside that of his son, Sir Lawrence Bragg, on North Terrace in Adelaide where he spent 23 years of his early career. Copyright © 2018. Published by Elsevier Ltd.

New Hypersonic Shock Tunnel at the Laboratory of Aerothermodynamics and Hypersonics Prof. Henry T. Nagamatsu

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toro, P. G. P.; Minucci, M. A. S.; Chanes, J. B. Jr

The new 0.60-m. nozzle exit diameter hypersonic shock tunnel was designed to study advanced air-breathing propulsion system such as supersonic combustion and/or laser technologies. In addition, it may be used for hypersonic flow studies and investigations of the electromagnetic (laser) energy addition for flow control. This new hypersonic shock tunnel was designed and installed at the Laboratory for of Aerothermodynamics and Hypersonics Prof. Henry T. Nagamatsu, IEAv-CTA, Brazil. The design of the tunnel enables relatively long test times, 2-10 milliseconds, suitable for the experiments performed at the laboratory. Free stream Mach numbers ranging from 6 to 25 can be producedmore » and stagnation pressures and temperatures up to 360 atm. and up to 9,000 K, respectively, can be generated. Shadowgraph and schlieren optical techniques will be used for flow visualization.« less

General Henry Arnold Visits the Aircraft Engine Research Laboratory

NASA Image and Video Library

1944-11-21

General Henry “Hap” Arnold, Commander of the US Army Air Forces during World War II, addresses the staff at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory on November 9, 1944. Arnold told the employees assembled in the hangar, “You’ve got a dual task. You’ve got a job ahead of you to keep the army and the navy air forces equipped with the finest equipment that you can for this war. You also have the job of looking forward into the future and starting now those developments, those experiments, that are going to keep us in our present situation—ahead of the world in the air. And that is quite a large order, and I leave it right in your laps.” Arnold served on the NACA’s Executive Committee in Washington from 1938 to 1944 and had been a strong advocate for the creation of the new engine research facility in Cleveland. Arnold believed in continual research and development. He pressed the nation’s aviation leaders to pursue the new jet engine technology, while simultaneously pushing to increase the performance of the nation’s largest piston engine for the B–29 Superfortress program. The general’s hectic wartime agenda limited his visit to the Cleveland laboratory to just a few hours, but he toured several of the NACA’s new test facilities including the Static Jet Propulsion Laboratory, the Icing Research Tunnel, and a B–24 Liberator in the hangar.

Finding the Big Bang

NASA Astrophysics Data System (ADS)

Peebles, P. James E.; Page, Lyman A., Jr.; Partridge, R. Bruce

2009-03-01

1. Introduction; 2. A guide to modern cosmology; 3. Origins of the cosmology of the 1960s; 4. Recollections of the 1960s Dave Hogg, Neville Woolf, George B. Field, Patrick Thaddeus, Donald E. Osterbrock, Yuri Nikolaevich Smirnov, Igor Dmitriyevich Novikov, Andrei Georgievich Doroshkevich, Rashid Alievich Sunyaev, Malcolm S. Longair, Arno Penzias, Robert W. Wilson, Bernard F. Burke, Kenneth C. Turner, P. James E. Peebles, David T. Wilkinson, Peter G. Roll, R. Bruce Partridge, Malcolm S. Longair, John Faulkner, Robert V. Wagoner, Martin Rees, Geoffrey R. Burbidge, Jayant V. Narlikar, David Layzer, Michele Kaufman, Jasper V. Wall, John Shakeshaft, William Welch, Kazimir S. Stankevich, Paul Boynton, Robert A. Stokes, Martin Harwit, Judith L. Pipher, Kandiah Shivanandan, Rainer Weiss, Jer-tsang Yu, Rainer K. Sachs, Arthur M. Wolfe, Joe Silk, George F. R. Ellis, Ronald N. Bracewell, Edward K. Conklin, Stephen Boughn, Karl C. Davis, Paul S. Henry; 5. Cosmology and the CMBR since the 1960s Dick Bond; Appendixes; Glossary; References; Index.

Government science in postwar America: Henry A. Wallace, Edward U. Condon, and the transformation of the National Bureau of Standards, 1945-1951.

PubMed

Lassman, Thomas C

2005-03-01

In the fall of 1945, Secretary of Commerce Henry Wallace handpicked Edward Condon, a respected theoretical physicist, to become director of the National Bureau of Standards. Already regarded by many academic and industrial scientists as a second-rate research institution, the Bureau had deteriorated further during the Great Depression. An ardent New Dealer who favored government action to prevent anticompetitive behavior in the marketplace, Wallace claimed that giant corporations leveraged their extensive patent holdings and research capabilities to manipulate markets and restrict competition at the expense of smaller firms without similar resources. Through a revitalized Bureau of Standards, Wallace intended to mitigate monopolistic behavior among large companies by transforming the Department of Commerce into an effective clearinghouse for scientific research that would stimulate technological innovation in small businesses. The Bureau's postwar expansion, however, foundered on congressional efforts to dismantle the legacies of the New Deal, Condon's lack of commitment to the technical requirements of the small business community, and the intense competition for resources within an institutionally pluralist federal research establishment dominated by the exigencies of the Cold War. Without sufficient financial support from congressional appropriations committees, Condon turned to the military to fund new research programs at the Bureau of Standards. These programs, however, owed their institutional growth to the demands of the national security state, not to the fading influence of Henry Wallace's New Deal liberalism.

A Guide to the Data Resources of the Henry A. Murray Research Center of Radcliffe College: A Center for the Study of Lives [and] Index to [the] Guide.

ERIC Educational Resources Information Center

Radcliffe Coll., Cambridge, MA. Henry A. Murray Research Center.

The first of two volumes provides information about data resources available at the Henry A. Murray Research Center of Radcliffe College, a multidisciplinary research center that is a national repository for social and behavioral science data on human development and social change; topics of special concern to women are collection priorities. The…

FRW cosmological models in Brans-Dicke theory of gravity with variable q and dynamical \\varLambda-term

NASA Astrophysics Data System (ADS)

Chand, Avtar; Mishra, R. K.; Pradhan, Anirudh

2016-02-01

Exact solution of modified Einstein's field equations are considered within the scope of spatially homogeneous and isotropic Fraidmann-Robertson-Walker (FRW) space-time filled with perfect fluid in the frame work of Brans-Dicke scalar-tensor theory of gravity. In this paper we have investigated the flat, open and closed FRW models and the effect of dynamic cosmological term on the evolution of the universe. Two types of FRW cosmological models are obtained by setting the power law between the scalar field φ and the scale factor a and deceleration parameter (DP) q as a time dependent. The concept of time dependent DP with some proper assumptions yield two type of the average scale factors (i) a(t)=[sinh(α t)]^{1/n} and (ii) a(t)=[t^{α}et]^{1/n}, α and n≠ 0 are arbitrary constants. In case (i), for 0 < n ≤ 1, it generates a class of accelerating models while for n > 1, the models of the universe exhibit phase transition from early decelerating to present accelerating phase and the transition redshift zt has been calculated and found to be in good agreement with the results from recent astrophysical observations. In case (ii), for n ≥ 2 and α = 1, we obtain a class of transit models of the universe from early decelerating to present accelerating phase. Taking into consideration the observational data, we conclude that the cosmological constant behaves as a positive decreasing function of time. The physical and geometric properties of the models are also discussed with the help of graphical presentations.

Temperature dependence of the Henry's law constant for hydrogen storage in NaA zeolites: a Monte Carlo simulation study.

PubMed

Sousa, João Miguel; Ferreira, António Luís; Fagg, Duncan Paul; Titus, Elby; Krishna, Rahul; Gracio, José

2012-08-01

Grand canonical Monte Carlo simulations of hydrogen adsorption in zeolites NaA were carried out for a wide range of temperatures between 77 and 300 K and pressures up to 180 MPa. A potential model was used that comprised of three main interactions: van der Waals, coulombic and induced polarization by the electric field in the system. The computed average number of adsorbed molecules per unit cell was compared with available results and found to be in agreement in the regime of moderate to high pressures. The particle insertion method was used to calculate the Henry coefficient for this model and its dependence on temperature.

Biobleaching of wheat straw-rich soda pulp with alkalophilic laccase from gamma-proteobacterium JB: optimization of process parameters using response surface methodology.

PubMed

Singh, Gursharan; Ahuja, Naveen; Batish, Mona; Capalash, Neena; Sharma, Prince

2008-11-01

An alkalophilic laccase from gamma-proteobacterium JB was applied to wheat straw-rich soda pulp to check its bleaching potential by using response surface methodology based on central composite design. The design was employed by selecting laccase units, ABTS (2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)) concentration and pH as model factors. The results of second order factorial design experiments showed that all three independent variables had significant effect on brightness and kappa number of laccase-treated pulp. Optimum conditions for biobleaching of pulp with laccase preparation (specific activity, 65 nkat mg(-1) protein) were 20 nkat g(-1) of pulp, 2mM ABTS and pH 8.0 which enhanced brightness by 5.89% and reduced kappa number by 21.1% within 4h of incubation at 55 degrees C, without further alkaline extraction of pulp. Tear index (8%) and burst index (18%) also improved for laccase-treated pulp as compared to control raw pulp. Treatment of chemically (CEH1H2) bleached pulp with laccase showed significant effect on release of chromophores, hydrophobic and reducing compounds. Laccase-prebleaching of raw pulp reduced the use of hypochlorite by 10% to achieve brightness of resultant hand sheets similar to the fully chemically bleached pulp.

Sir Henry Solomon Wellcome and Dr Andrew Balfour: an enterprise on the Nile and the early foundation of public health and medical research in the Sudan (1899-1935).

PubMed

Elhadd, T A

2015-01-01

In Sudan, modern medical practice and medical research began soon after the creation of Anglo-Egyptian Sudan at the turn of the 20th century. The benevolent involvement of Sir Henry Solomon Wellcome, and the ingenious feat of his protégé Sir Andrew Balfour, was crucial to the strong foundation of that establishment. Sir Henry Wellcome provided the financial sponsorship plus influential, logistical and moral support. Dr Balfour put great energy into making the enterprise one of the most amazing medical achievements in colonial medicine. Improvement in the public health of the capital Khartoum was emulated by other doctors working in this vast country. Research was not restricted to tropical medicine; it also encompassed agricultural and chemical research. This helped with the establishment of the first modern medical school in the country in 1924 and resulted in the medical service in Sudan being described as one of the best in the world. Many British doctors flocked to Sudan to make a fortune and to set a path for their career back in Britain.

Laboratory testing for the diagnosis, evaluation, and management of systemic lupus erythematosus: Still more questions for the next generations: A Tribute and Thanks and in Memory of my mentor: Henry G. Kunkel.

PubMed

Schur, Peter H

2016-11-01

This paper is a review, personal memoir, a tribute to Henry Kunkel, and a critique regarding laboratory tests used for the evaluation, diagnosis, and understanding Autoimmune Rheumatic Diseases, in particular systemic lupus erythematosus (SLE). Copyright © 2016 Elsevier Inc. All rights reserved.

Real-world automotive emissions—Summary of studies in the Fort McHenry and Tuscarora mountain tunnels

NASA Astrophysics Data System (ADS)

Pierson, William R.; Gertler, Alan W.; Robinson, Norman F.; Sagebiel, John C.; Zielinska, Barbara; Bishop, Gary A.; Stedman, Donald H.; Zweidinger, Roy B.; Ray, William D.

Motor vehicle emission rates of CO, NO, NO x, and gas-phase speciated nonmethane hydrocarbons (NMHC) and carbonyl compounds were measured in 1992 in the Fort McHenry Tunnel under Baltimore Harbor and in the Tuscarora Mountain Tunnel of the Pennsylvania Turnpike, for comparison with emission-model predictions and for calculation of the reactivity of vehicle emissions with respect to O 3 formation. Both tunnels represent a high-speed setting at relatively steady speed. The cars at both sites tended to be newer than elsewhere (median age was < 4 yr), and much better maintained as judged by low CO/CO2 ratios and other emissions characteristics. The Tuscarora Mountain Tunnel is flat, making it advantageous for testing automotive emission models, while in the underwater Fort McHenry Tunnel the impact of roadway grade can be evaluated. MOBILE4.1 and MOBILES gave predictions within ± 50% of observation most of the time. There was a tendency to overpredict, especially with MOBILES and especially at Tuscarora. However, light-duty-vehicle CO, NMHC, and NO x, all were underpredicted by MOBILE4.1 at Fort McHenry. Light-duty-vehicle CO/NOx ratios and NMHC/NO x, ratios were generally a little higher than predicted. The comparability of the predictions to the observations contrasts with a 1987 experiment in an urban tunnel (Van Nuys) where CO and HC, as well as CO/NOx, and NMHC/NO x, ratios, were grossly underpredicted. The effect of roadway grade on gram per mile (g mi -1) emissions was substantial. Fuel-specific emissions (g gal -1), however, were almost independent of roadway grade, which suggests a potential virtue in emissions models based on fuel-specific emissions rather than g mi -1) emissions. Some 200 NMHC and carbonyl emissions species were quantified as to their light- and heavy-duty-vehicle emission rates. The heavy-duty-vehicle NMHC emissions were calculated to possess more reactivity, per vehicle-mile, with respect to O 3 formation (g O 3 per vehicle-mile) than did

The impact of HENRY on parenting and family lifestyle: A national service evaluation of a preschool obesity prevention programme.

PubMed

Willis, T A; Roberts, K P J; Berry, T M; Bryant, M; Rudolf, M C J

2016-07-01

One in five children in England are overweight/obese at school entry. Tackling obesity is therefore a priority. Right from the Start with HENRY is a widely-commissioned programme delivered by trained facilitators to small groups of parents over eight weekly sessions. It is designed to provide parents of infants and preschool children with the skills, knowledge and confidence required for a healthier family lifestyle. The aim of this work was to investigate programme impact using data collected routinely for quality control purposes. Analysis of routinely collected pre-post data from programmes delivered in the UK from January 2012 to February 2014. Data were analysed from 144 programmes, including questionnaires relating to parenting, family eating behaviours, dietary intake, and physical activity/screen time. Over 24 months, 1100 parents attended programmes running in 86 locations. 788 (72%) completed >5 sessions of whom 624 (79%) provided baseline and completion questionnaires. Parents reported increases in healthiness of family lifestyle, parenting attributes, and emotional wellbeing following attendance (all P < .001). Both parents and children were reported to have increased their daily fruit/vegetable consumption, and reduced their consumption of high fat/sugar foods (both P < .001). There were also positive changes in eating behaviours, physical activity (P < .001) and children's screen time (P < .001). Significant changes were reported in all domains similar to those reported in a previous, smaller study in locations selected for experience and quality. The HENRY approach appears to have a beneficial impact even when delivered at scale in non-selected locations. Such changes, if maintained, may serve to protect against later obesity. Copyright © 2016 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Henri Collomb and the emergence of a psychiatry open to otherness through interdisciplinary dialogue in post-independence Dakar.

PubMed

Collignon, René

2018-06-01

During decolonization, Henri Collomb was appointed to the first Chair of Psychiatry at the University of Dakar. Using a neuropsychiatric approach, he quickly made significant advances in the field, despite the colonial era's poor legacy of assistance facilities for mentally ill people. Through alliances with professors and researchers from the university Departments of Psychology and Sociology, an original interdisciplinary dialogue was set up to build up a research team which would develop rich and varied activities in the fields of transcultural psychiatry, medical anthropology and psychoanalytic anthropology. The methodological and theoretical contributions of such an approach are well illustrated in the book Œdipe africain by M-C and E Ortigues and in the journal founded in 1965, Psychopathologie africaine.

Tools for groundwater protection planning: An example from McHenry County, Illinois, USA

USGS Publications Warehouse

Berg, R.C.; Curry, B. Brandon; Olshansky, R.

1999-01-01

This paper presents an approach for producing aquifer sensitivity maps from three-dimensional geologic maps, called stack-unit maps. Stack-unit maps depict the succession of geologic materials to a given depth, and aquifer sensitivity maps interpret the successions according to their ability to transmit potential contaminants. Using McHenry County, Illinois, as a case study, stack-unit maps and an aquifer sensitivity assessment were made to help land-use planners, public health officials, consultants, developers, and the public make informed decisions regarding land use. A map of aquifer sensitivity is important for planning because the county is one of the fastest growing counties in the nation, and highly vulnerable sand and gravel aquifers occur within 6 m of ground surface over 75% of its area. The aquifer sensitivity map can provide guidance to regulators seeking optimal protection of groundwater resources where these resources are particularly vulnerable. In addition, the map can be used to help officials direct waste-disposal and industrial facilities and other sensitive land-use practices to areas where the least damage is likely to occur, thereby reducing potential future liabilities.

Henry Wade (1876-1955), pioneer of urological surgery, museum conservator and war veteran.

PubMed

Gardner, Dugald

2017-01-01

Henry Wade graduated in the Edinburgh Medical School in 1898 before spending two years with the British army during the Anglo-Boer war. Returning to this country, he joined Francis Caird, surgeon to the Edinburgh Royal Infirmary. Appointed Conservator of the museum of the Royal College of Surgeons of Edinburgh, Wade met young William Ford Robertson. In a study of experimental cancer they concluded that some neoplasms were caused by bacteria. Wade became increasingly recognised as an authority in urology. His growing practice was interrupted by the First World War. Already a member of the Royal Army Medical Corps, he served for five years in the Middle East, in Gallipoli and then with the army in an approach to Jerusalem. Resuming civilian life, Wade combined an extensive urological practice with membership of the Council of the RCSEd. He became President in 1935. Married in 1924, his wife died four years later after an operation by a colleague, David Wilkie. Director of Surgery to the Scottish Emergency Medical Service when the Second World War broke out, Wade was made a Knight Bachelor in 1946. He died in 1955.

Derivation of the MMPI-2-RF Henry-Heilbronner Index-r (HHI-r) scale.

PubMed

Henry, George K; Heilbronner, Robert L; Algina, James; Kaya, Yasemin

2013-01-01

The 15-item Henry-Heilbronner Index (HHI) was published in 2006 as an MMPI-2 embedded measure of psychological response validity. When the MMPI-2 was revised in 2008 only 11 of the 15 original HHI items were retained on the MMPI-2-RF, prohibiting use of the HHI as an embedded validity indicator on the MMPI-2-RF. Using the original HHI sample an 11-item version of the HHI, the HHI-r, was evaluated for use as an embedded measure of psychological response validity for the MMPI-2-RF. The 11-item HHI-r was very similar to the HHI in classification accuracy. An HHI-r cutoff score of ≥7 was associated with a classification accuracy rate of 84.0%, good sensitivity (68.9%), and high specificity (93.2%) in identifying symptom exaggeration in personal injury and disability litigants versus non-litigating head-injured patients. These preliminary results suggest the HHI-r functions in a manner similar to the original HHI as a measure of psychological response validity, and may be used by psychologists and neuropsychologists as an MMPI-2-RF embedded validity indicator.

Modeling hydrodynamics, temperature and water quality in Henry Hagg Lake, Oregon, 2000-2003

USGS Publications Warehouse

Sullivan, Annette B.; Rounds, Stewart A.

2004-01-01

The two-dimensional model CE-QUAL-W2 was used to simulate hydrodynamics, temperature, and water quality in Henry Hagg Lake, Oregon, for the years 2000 through 2003. Input data included lake bathymetry, meteorologic conditions, tributary inflows, tributary temperature and water quality, and lake outflows. Calibrated constituents included lake hydrodynamics, water temperature, orthophosphate, total phosphorus, ammonia, algae, chlorophyll a, zooplankton, and dissolved oxygen. Other simulated constituents included nitrate, dissolved and particulate organic matter, dissolved solids, and suspended sediment. Two algal groups (blue-green algae, and all other algae) were included in the model to simulate the lakes algal communities. Measured lake stage data were used to calibrate the lakes water balance; calibration of water temperature and water quality relied upon vertical profile data taken in the deepest part of the lake near the dam. The model initially was calibrated with data from 200001 and tested with data from 200203. Sensitivity tests were performed to examine the response of the model to specific parameters and coefficients, including the light-extinction coefficient, wind speed, tributary inflows of phosphorus, nitrogen and organic matter, sediment oxygen demand, algal growth rates, and zooplankton feeding preference factors.

A Brief Overview of the Life and Work of Lyon Henry Appleby, M.D. (1895-1970).

PubMed

Harrison, Jon; Pucci, Michael J; Cowan, Scott W; Yeo, Charles J

2016-12-01

The life and work of Dr. Lyon Henry Appleby, M.D., portrays the essence of a devoted clinician committed to scholarly excellence. Born in Deseronto, Ontario, in 1895 and passing in 1970, Dr. Appleby influenced all areas of general surgery, most notably popularizing a procedure that bears his name today. After a tour in World War I, he quickly proved himself to be a dedicated clinician with roots in academia, which translated into excellence within the Department of Surgery at St. Paul's Hospital in Vancouver, Canada. He served in various leadership roles including Chair of the Department of Surgery, President of the International College of Surgeons, and Fellow of the Royal College of Physicians and Surgeons. The Appleby procedure, or en bloc removal of the celiac axis, at the time of gastrectomy, is the technical focus of this paper, although reference is made to Appleby's extensive contributions to historical medicine.

Charged black holes in string-inspired gravity II. Mass inflation and dependence on parameters and potentials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, Jakob; Yeom, Dong-han, E-mail: hansen@kisti.re.kr, E-mail: innocent.yeom@gmail.com

2015-09-01

We investigate the relation between the existence of mass inflation and model parameters of string-inspired gravity models. In order to cover various models, we investigate a Brans-Dicke theory that is coupled to a U(1) gauge field. By tuning a model parameter that decides the coupling between the Brans-Dicke field and the electromagnetic field, we can make both of models such that the Brans-Dicke field is biased toward strong or weak coupling directions after gravitational collapses. We observe that as long as the Brans-Dicke field is biased toward any (strong or weak) directions, there is no Cauchy horizon and no massmore » inflation. Therefore, we conclude that to induce a Cauchy horizon and mass inflation inside a charged black hole, either there is no bias of the Brans-Dicke field as well as no Brans-Dicke hair outside the horizon or such a biased Brans-Dicke field should be well trapped and controlled by a potential.« less

Charged black holes in string-inspired gravity II. Mass inflation and dependence on parameters and potentials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hansen, Jakob; Yeom, Dong-han

2015-09-07

We investigate the relation between the existence of mass inflation and model parameters of string-inspired gravity models. In order to cover various models, we investigate a Brans-Dicke theory that is coupled to a U(1) gauge field. By tuning a model parameter that decides the coupling between the Brans-Dicke field and the electromagnetic field, we can make both of models such that the Brans-Dicke field is biased toward strong or weak coupling directions after gravitational collapses. We observe that as long as the Brans-Dicke field is biased toward any (strong or weak) directions, there is no Cauchy horizon and no massmore » inflation. Therefore, we conclude that to induce a Cauchy horizon and mass inflation inside a charged black hole, either there is no bias of the Brans-Dicke field as well as no Brans-Dicke hair outside the horizon or such a biased Brans-Dicke field should be well trapped and controlled by a potential.« less

'A Speculative Idea': The Parallel Trajectories of Financial Speculation, Obstetrical Science, and Fiscal Management of Female Bodies in Henry James's Washington Square.

PubMed

Nixon, Kari

2017-09-01

This essay teases out the intimate connections between the scientific and fiscal realms in the context of American germ theory and obstetrics. By uncovering the economic and medical contexts of Henry James's Washington Square-set during the infancy of germ theory and the heyday of American obstetrics-this essay exposes a previously unexplored subtextual history of contagion in the text. Although this scientific history seems relegated to the novel's margins, understanding the changing scientific cosmologies and professional organizations in the context of the novel's setting and composition reveals that these tiny infectious particles and their vectors fundamentally shape the plot of the novel.

A personal tribute to a great educator: how Henry Kawamoto influenced my interest in facial soft tissue anatomy and changed my plastic surgery career.

PubMed

Stuzin, James M

2012-11-01

Henry Kawamoto remains one of the most influential craniofacial surgeons of the 20th century. A Tessier-trained craniofacial surgeon, Dr. Kawamoto has personally influenced not only the lives of his patients, but significantly also the lives of those craniofacial fellows he educated, passing on the Tessier methodology to future generations. This article serves as an anecdote as to how Dr. Kawamoto's mentoring influenced a personal understanding of facial soft tissue anatomy, leading to improved technical approaches for surgical rejuvenation of the aging face.

Promoting good health in the age of reform: the medical publications of Henry H. Porter of Philadelphia, 1829-32.

PubMed

Horrocks, T A

1995-01-01

In the early 1830s, the Philadelphia publisher Henry H. Porter rapidly published five journals, six books, and an almanac, works having a particular emphasis on health and personal hygiene. Porter's health publications linked the traditional message about the importance of personal hygiene to health to the messages conveyed by the flourishing American reform movements at the time, and his Journal of Health was among the first American medically oriented periodicals published for the layperson. Yet Porter did not survive in the intensely competitive and financially unstable book trade. This study examines Porter's health publications, attempting to explain why he chose to publish what he did, the message(s) his works contained, the audience(s) he tried to reach, and the failure of his business.

Generation of sub-part-per-billion gaseous volatile organic compounds at ambient temperature by headspace diffusion of aqueous standards through decoupling between ideal and nonideal Henry's law behavior.

PubMed

Kim, Yong-Hyun; Kim, Ki-Hyun

2013-05-21

In the analysis of volatile organic compounds in air, the preparation of their gaseous standards at low (sub-ppb) concentration levels with high reliability is quite difficult. In this study, a simple dynamic headspace-based approach was evaluated as a means of generating vapor-phase volatile organic compounds from a liquid standard in an impinger at ambient temperature (25 °C). For a given sampling time, volatile organic compound vapor formed in the headspace was swept by bypassing the sweep gas through the impinger and collected four times in quick succession in separate sorbent tubes. In each experiment, a fresh liquid sample was used for each of the four sampling times (5, 10, 20, and 30 min) at a steady flow rate of 50 mL min(-1). The air-water partitioning at the most dynamic (earliest) sweeping stage was established initially in accord with ideal Henry's law, which was then followed by considerably reduced partitioning in a steady-state equilibrium (non-ideal Henry's law). The concentrations of gaseous volatile organic compounds, collected after the steady-state equilibrium, reached fairly constant values: for instance, the mole fraction of toluene measured at a sweeping interval of 10 and 30 min averaged 1.10 and 0.99 nmol mol(-1), respectively (after the initial 10 min sampling). In the second stage of our experiment, the effect of increasing the concentrations of liquid spiking standard was also examined by collecting sweep gas samples from two consecutive 10 min runs. The volatile organic compounds, collected in the first and second 10 min sweep gas samples, exhibited ideal and nonideal Henry's law behavior, respectively. From this observation, we established numerical relationships to predict the mole fraction (or mixing ratio) of each volatile organic compound in steady-state equilibrium in relation to the concentration of standard spiked into the system. This experimental approach can thus be used to produce sub-ppb levels of gaseous volatile organic

Effects of temperature, pH, and ionic strength on the Henry's law constant of triethylamine

NASA Astrophysics Data System (ADS)

Leng, Chun-Bo; Roberts, Jason E.; Zeng, Guang; Zhang, Yun-Hong; Liu, Yong

2015-05-01

The Henry's law constants (KH) of triethylamine (TEA) in pure water and in 1-octanol were measured for the temperatures pertinent to the lower troposphere (278-298 K) using a bubble column system coupled to a Fourier transform infrared spectrometer. The KH values of TEA in water and 1-octanol at 298 K are 5.75 ± 0.86 mol L-1 atm-1 and 115.62 ± 5.78 mol L-1 atm-1. The KH values display strong dependence on temperature, pH, and ionic strength. The characteristic times for TEA to establish an equilibrium between gas and droplet with a size of 5.6 µm are ~33 s (298 K, pH = 5.6); ~8.9 × 102 s (278 K, pH = 5.6); ~1.3 × 103 s (298 K, pH = 4.0); and 3.6 × 104 s (278 K, pH = 4.0). The evaluation of TEA partitioning between gas phase and condensed phase implies that TEA predominantly resides in rainwater, and TEA loss to organic aerosol is negligible.

Dynamical systems theory and applications

NASA Astrophysics Data System (ADS)

Awrejcewicz, Jan

2006-08-01

The 7th International Conference devoted to "Dynamical Systems-Theory and Applications" hold in 8-11 December, 2003 in Łódź, Poland, and it was organized by the staff of Department of Automatics and Biomechanics of the Technical University of Łódź. It was financially supported by the Rector of the Technical University of Łódź and the Department of Education and Physical Culture of the Łódź City Hall. The members of the International Scientific Committee included: Igor V. Andrianov (Dniepropetrovsk), Jan Awrejcewicz (Łódź), Iliya Blekhman (Sankt Petersburg), Roman Bogacz (Warszawa), Dick van Campen (Eindhoven), Zbigniew Engel (Kraków), Lothar Gaul (Stuttgart), Józef Giergiel (Kraków), Michał Kleiber (Warszawa), Vadim A. Krysko (Saratov), Włodzimierz Kurnik (Warszawa), Claude-Henri Lamarque (Lyon), Leonid I. Manevitch (Moscow), Jan Osiecki (Warszawa), Wiesaw Ostachowicz (Gdańsk), Ladislav Pust (Prague), Giuseppe Rega (Rome), Tsuneo Someya (Tokyo), Zbigniew Starczewski (Warszawa), Eugeniusz Świtoński (Gliwice), Andrzej Tylikowski (Warszawa), Tadeusz Uhl (Kraków), Aleksander F. Vakakis (Illinois), Józef Wojnarowski (Gliwice).

Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells.

PubMed

Liu, G; Bibus, D M; Bode, A M; Ma, W Y; Holman, R T; Dong, Z

2001-06-19

Epidemiological and animal-based investigations have indicated that the development of skin cancer is in part associated with poor dietary practices. Lipid content and subsequently the derived fatty acid composition of the diet are believed to play a major role in the development of tumorigenesis. Omega 3 (omega3) fatty acids, including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), can effectively reduce the risk of skin cancer whereas omega 6 (omega6) fatty acids such as arachidonic acid (AA) reportedly promote risk. To investigate the effects of fatty acids on tumorigenesis, we performed experiments to examine the effects of the omega3 fatty acids EPA and DHA and of the omega6 fatty acid AA on phorbol 12-tetradecanoate 13-acetate (TPA)-induced or epidermal growth factor (EGF)-induced transcription activator protein 1 (AP-1) transactivation and on the subsequent cellular transformation in a mouse epidermal JB6 cell model. DHA treatment resulted in marked inhibition of TPA- and EGF-induced cell transformation by inhibiting AP-1 transactivation. EPA treatment also inhibited TPA-induced AP-1 transactivation and cell transformation but had no effect on EGF-induced transformation. AA treatment had no effect on either TPA- or EGF-induced AP-1 transactivation or transformation, but did abrogate the inhibitory effects of DHA on TPA- or EGF-induced AP-1 transactivation and cell transformation in a dose-dependent manner. The results of this study demonstrate that the inhibitory effects of omega3 fatty acids on tumorigenesis are more significant for DHA than for EPA and are related to an inhibition of AP-1. Similarly, because AA abrogates the beneficial effects of DHA, the dietary ratio of omega6 to omega3 fatty acids may be a significant factor in mediating tumor development.

[The turn of the screw: complex visual hallucinations in the Henry James' novel].

PubMed

Alvaro, L C; Martín Del Burgo, A

2002-03-01

The turn of the screw is one of the most celebrated stories by Henry James. It is also a top writing within the so-called fantastic literature, whose narrative strength comes from the intermittent visions suffered by the main character. The vividness and dramatic content that represent the firstly unidentified human figures, that moreover recur as brief, stereotyped and fragmentary images, are constitutive of complex visual hallucinations. These characteristics, alongside acute premonitory symptoms such as emotional changes (fear, anxiety) or altered thinking (forced, "dejà vu", "jamais vu"), and the final altered awareness or loss of consciousness, allow us to infer an epileptic nature of the ten episodes described. Postictal psychosis, that follows a lucid interval and may last up to the several weeks encompassed by the story, would account for the paranoia featured, in the setting of a temporal lobe epilepsy. The accurate descriptions prompted us to search for autobiographical, scientific or literary influences: The alcoholism and visual hallucinations suffered by his father, the knowledge on hallucinations provided by his brother Williams on his paramount and former The Principles of Psychology, and an early devotion to Poe's writings, an epileptic himself with excellent descriptions of seizures in his writings, might have enabled the author to perform his story with such a hallmark of neurological details.

How to boost soundscapes with tax breaks-On the application of Henry George's environmental economics to noise annoyance

NASA Astrophysics Data System (ADS)

Hehner, Cay

2004-05-01

The improvement of the characteristic soundscape in a given metropolitan area depends largely on a varied number of parameters not the least of which are economic. The way to sustain a large city not only economically responsible behavior patterns and activities are required, but ecologically viable ones as well. And, not coincidentally, if both patterns come into balance, a reduction of noise annoyance ensues. The cohesive set of measures that would provide the framework to ensure that the necessary economic activity is not antagonistic to (acoustic) ecology is provided by the US economist Henry George who advocated a comprehensive tax on land and all natural resources to replace eventually the bulk of all taxes checking production. New data will be provided in this paper to show the results of the application of a Georgist approach of eco-taxation to the improvement of sound quality and the reduction of noise annoyance.

2D X-ray and FTIR micro-analysis of the degradation of cadmium yellow pigment in paintings of Henri Matisse

NASA Astrophysics Data System (ADS)

Pouyet, E.; Cotte, M.; Fayard, B.; Salomé, M.; Meirer, F.; Mehta, A.; Uffelman, E. S.; Hull, A.; Vanmeert, F.; Kieffer, J.; Burghammer, M.; Janssens, K.; Sette, F.; Mass, J.

2015-11-01

The chemical and physical alterations of cadmium yellow (CdS) paints in Henri Matisse's The Joy of Life (1905-1906, The Barnes Foundation) have been recognized since 2006, when a survey by portable X-ray fluorescence identified this pigment in all altered regions of the monumental painting. This alteration is visible as fading, discoloration, chalking, flaking, and spalling of several regions of light to medium yellow paint. Since that time, synchrotron radiation-based techniques including elemental and spectroscopic imaging, as well as X-ray scattering have been employed to locate and identify the alteration products observed in this and related works by Henri Matisse. This information is necessary to formulate one or multiple mechanisms for degradation of Matisse's paints from this period, and thus ensure proper environmental conditions for the storage and the display of his works. This paper focuses on 2D full-field X-ray Near Edge Structure imaging, 2D micro-X-ray Diffraction, X-ray Fluorescence, and Fourier Transform Infra-red imaging of the altered paint layers to address one of the long-standing questions about cadmium yellow alteration—the roles of cadmium carbonates and cadmium sulphates found in the altered paint layers. These compounds have often been assumed to be photo-oxidation products, but could also be residual starting reagents from an indirect wet process synthesis of CdS. The data presented here allow identifying and mapping the location of cadmium carbonates, cadmium chlorides, cadmium oxalates, cadmium sulphates, and cadmium sulphides in thin sections of altered cadmium yellow paints from The Joy of Life and Matisse's Flower Piece (1906, The Barnes Foundation). Distribution of various cadmium compounds confirms that cadmium carbonates and sulphates are photo-degradation products in The Joy of Life, whereas in Flower Piece, cadmium carbonates appear to have been a [(partially) unreacted] starting reagent for the yellow paint, a role

Henry Cavendish (1731-1810): hydrogen, carbon dioxide, water, and weighing the world.

PubMed

West, John B

2014-07-01

Henry Cavendish (1731-1810) was an outstanding chemist and physicist. Although he was not a major figure in the history of respiratory physiology he made important discoveries concerning hydrogen, carbon dioxide, atmospheric air, and water. Hydrogen had been prepared earlier by Boyle but its properties had not been recognized; Cavendish described these in detail, including the density of the gas. Carbon dioxide had also previously been studied by Black, but Cavendish clarified its properties and measured its density. He was the first person to accurately analyze atmospheric air and reported an oxygen concentration very close to the currently accepted value. When he removed all the oxygen and nitrogen from an air sample, he found that there was a residual portion of about 0.8% that he could not characterize. Later this was shown to be argon. He produced large amounts of water by burning hydrogen in oxygen and recognized that these were its only constituents. Cavendish also worked on electricity and heat. However, his main contribution outside chemistry was an audacious experiment to measure the density of the earth, which he referred to as "weighing the world." This involved determining the gravitational attraction between lead spheres in a specially constructed building. Although this was a simple experiment in principle, there were numerous complexities that he overcame with meticulous attention to experimental details. His result was very close to the modern accepted value. The Cavendish Experiment, as it is called, assures his place in the history of science. Copyright © 2014 the American Physiological Society.

Bayard Holmes (1852-1924) and Henry Cotton (1869-1933): Surgeon-psychiatrists and their tragic quest to cure schizophrenia.

PubMed

Davidson, Jonathan

2016-11-01

Early 20th-century medicine was dominated by the infectious theory of disease. Some leading physicians believed that infection or the accumulation of toxic substances from bacterial stasis caused a wide range of diseases, including schizophrenia. In the case of schizophrenia, one theory held that intestinal stasis lead to the bacterial production of toxins that affected brain function, resulting in psychotic illness. This theory predicted that clearing the stasis by drainage or by removal of the offending organ would be curative. Bayard Holmes and Henry Cotton, surgeon-psychiatrists, achieved notoriety for their efforts to cure schizophrenia surgically. Their endeavours were not only a failure but resulted in tragedy to their families and to a wider population. Treatment of their own sons also represented a violation of the ethics of their time. This account describes the life and career of Holmes and Cotton and reappraises their work in the light of recent developments. © IMechE 2014.

Geologic investigation of layered mound of Henry Crater, Mars: Implications for history of ancient hydrological activities in the region

NASA Astrophysics Data System (ADS)

Sarkar, Samarpita; Sinha, Rishitosh Kumar; Banerjee, Debabrata; Vijayan, S.

2016-07-01

Craters around the Schiaparelli Basin (sim460 km diameter; 2.71^circS 16.77^circE) on Mars are distributed in a unique combination that includes infilled craters with mound on their floors. The mounds have preserved intriguing layers in stratigraphy that has exposed pristine sets of geomorphic and geochemical signatures bearing strong implications towards understanding geological history of Mars. With a view to avail the maximum scientific benefit from this unique geological assemblage on Mars, we have carried out remote analysis of stratigraphy of layers exposed over Henry crater's (sim150 km diameter; 10.79^circN 23.45^circE) mound (rising sim2km from floor) to infer the origin and episodes of geological events occurred in the region. Henry crater is situated approximately 500 km northeast of Schiaparelli Basin. Using crater counting technique the age of the topmost surface of the crater mound is found to be sim3.64 Ga since the exposure of this strata post complete infilling. The stratigraphy of consistent and conformable layers in the crater interior acts as a proxy of the long-lived event of sediment deposition in a rather quiescent condition. Distinct layering can be traced across the crater from the mound to the crater wall across the floor. Evidence for differential erosion of deposited materials, wherein local geological setup developed in the different parts of the crater interior is preserved. Using MRO HiRISE & CTX images, distinct spatial distribution of morphological features distributed in stratigraphy is observed that reveals the dominant geological agents behind their formation, viz. temporal hydrological and eolian processes. The morphological features were aided with an understanding of the composition of the exposed sedimentary succession. MRO CRISM based mineralogical investigation reveals diagnostic signature of the hydrated sulfate mineral Kieserite. Based on the thermodynamic properties of Kieserite and apparent lack of desiccation cracks in

Henry Knowles Beecher, Jay Katz, and the Transformation of Research with Human Beings.

PubMed

Capron, Alexander Morgan

2016-01-01

The modern history of experimentation with human beings is notable for its ethical lacunae, when even the clearest directives fail to prevent violations of subjects' rights and welfare. One such lacuna occurred during the 25 years between 1947, when the Nuremberg Code was articulated in the judgment passed on the men who had performed medical experiments in the Nazi concentration camps, and 1972, when the revelation of the 40-year-long Tuskegee Syphilis Study shocked the public and pushed Congress to adopt legislation that eventually transformed the governance of human subjects research. The work that Henry Beecher and Jay Katz did on the ethics of human experimentation beginning in 1964-which was mutually supportive but also divergent in its premises and prescriptions-played a prominent role in the policy-making processes. Beecher, whose detailed disclosure of the ethical lapses of leading researchers in his renowned 1966 New England Journal of Medicine article initiated the policy reform process, proved less influential in shaping those reforms than Katz. Ultimately, Beecher was one of the last and best exemplars of "medical ethics," while Katz-in his service on the Tuskegee Syphilis Study Ad Hoc Advisory Panel and in his testimony before, and work with, the Senate Health subcommittee-was an early practitioner of bioethics, a field in which the rules are not all written and applied by the medical profession but arise through a messier process involving outsiders and formal regulatory decisions.

Deviation Management: Key Management Subsystem Driver of Knowledge-Based Continuous Improvement in the Henry Ford Production System.

PubMed

Zarbo, Richard J; Copeland, Jacqueline R; Varney, Ruan C

2017-10-01

To develop a business subsystem fulfilling International Organization for Standardization 15189 nonconformance management regulatory standard, facilitating employee engagement in problem identification and resolution to effect quality improvement and risk mitigation. From 2012 to 2016, the integrated laboratories of the Henry Ford Health System used a quality technical team to develop and improve a management subsystem designed to identify, track, trend, and summarize nonconformances based on frequency, risk, and root cause for elimination at the level of the work. Programmatic improvements and training resulted in markedly increased documentation culminating in 71,641 deviations in 2016 classified by a taxonomy of 281 defect types into preanalytic (74.8%), analytic (23.6%), and postanalytic (1.6%) testing phases. The top 10 deviations accounted for 55,843 (78%) of the total. Deviation management is a key subsystem of managers' standard work whereby knowledge of nonconformities assists in directing corrective actions and continuous improvements that promote consistent execution and higher levels of performance. © American Society for Clinical Pathology, 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

The unknown planktonic foraminiferal pioneer Henry A. Buckley and his collection at The Natural History Museum, London

NASA Astrophysics Data System (ADS)

Rillo, Marina C.; Whittaker, John; Ezard, Thomas H. G.; Purvis, Andy; Henderson, Andrew S.; Stukins, Stephen; Miller, C. Giles

2016-12-01

The Henry Buckley Collection of Planktonic Foraminifera at the Natural History Museum in London (NHMUK) consists of 1665 single-taxon slides housing 23 897 individuals from 203 sites in all the major ocean basins, as well as a vast research library of Scanning Electron Microscope (SEM) photomicrographs. Buckley picked the material from the NHMUK Ocean-Bottom Deposit Collection and also from fresh tow samples. However, his collection remains largely unused as he was discouraged by his managers in the Mineralogy Department from working on or publicizing the collection. Nevertheless, Buckley published pioneering papers on isotopic interpretation of oceanographic and climatic change and was one of the first workers to investigate foraminiferal wall structure using the SEM technique. Details of the collection and images of each slide are available via the NHMUK Data Portal (http://dx.doi.org/10.5519/0035055). The Buckley Collection and its associated Ocean-Bottom Deposit Collection have great potential for taxon-specific studies as well as geochemical work, and both collections are available on request.

Impact of economic fluctuations on suicide mortality in Canada (1926-2008): Testing the Durkheim, Ginsberg, and Henry and Short theories.

PubMed

Thibodeau, Lise; Lachaud, James

2016-01-01

Three theories have been proposed to explain the relationship between suicide and economic fluctuations, including the Durkheim (nonlinear), Ginsberg (procyclical), and Henry and Short (countercyclical) theories. This study tested the effect of economic fluctuations, measured by unemployment rate, on suicide rates in Canada from 1926 to 2008. Autoregressive integrated moving average time-series models were used. The results showed a significant relationship between suicide and economic fluctuation; this association was positive during the contraction period (1926-1950) and negative in the period of economic expansion (1951-1973). Males and females showed differential effects in the period of moderate unemployment (1974-2008). In addition, the suicide rate of mid-adults (45-64) was most impacted by economic fluctuations. Our study tends to support Durkheim's theory and suggests the need for public health responses in times of economic contraction and expansion.

Clinical spectrum of patients with erosion of the inner ear by jugular bulb abnormalities.

PubMed

Friedmann, David R; Le, B Thuy; Pramanik, Bidyut K; Lalwani, Anil K

2010-02-01

Anatomic variants of the jugular bulb (JB) are common; however, abnormalities such as large high riding JB and JB diverticulum (JBD) are uncommon. Rarely, the abnormal JB may erode into the inner ear. The goal of our study is to report a large series of patients with symptomatic JB erosion into the inner ear. Retrospective review in an academic medical center. Eleven patients with JB abnormality eroding into the inner ear were identified on computed tomography (CT) scan of the temporal bone. Age at presentation was from 5 years to 82 years with six males and five females. The large JB or JBD eroded into the vestibular aqueduct (n = 9) or the posterior semicircular canal (n = 4). The official radiology report usually identified the JB abnormality; however, erosion into these structures by the JB was not mentioned in all but one case. All patients were symptomatic with five having conductive hearing loss (CHL) and three complaining of pulsatile tinnitus. Those with pulsatile tinnitus and four of five with CHL had erosion into the vestibular aqueduct. Vestibular evoked myogenic potential (VEMP) findings in three of six patients were consistent with dehiscence of the inner ear. High riding large JB or JBD can erode into the inner ear and may be associated with CHL and/or pulsatile tinnitus. CT scan is diagnostic and should be examined specifically for these lesions. As patients with pulsatile tinnitus may initially undergo a magnetic resonance imaging scan, identification of JB abnormality should prompt CT scan or VEMP testing to evaluate for inner ear erosion.

Jolkinolide B induces apoptosis of colorectal carcinoma through ROS-ER stress-Ca2+-mitochondria dependent pathway

PubMed Central

Zhang, Jing; Wang, Yang; Zhou, Ye; He, Qing-Yu

2017-01-01

Colorectal carcinoma (CRC) remains one of the leading causes of death in cancer-related diseases. In this study, we aimed to investigate the anticancer effect of Jolkinolide B (JB), a bioactive diterpenoid component isolated from the dried roots of Euphorbia fischeriana Steud, on CRC cells and its underlying mechanisms. We found that JB suppressed the cell viability and colony formation of CRC cells, HT29 and SW620. Annexin V/PI assay revealed that JB induced apoptosis in CRC cells, which was further confirmed by the increased expression of cleaved-caspase3 and cleaved-PARP. iTRAQ-based quantitative proteomics was performed to identify JB-regulated proteins in CRC cells. Gene Ontology (GO) analysis revealed that these JB-regulated proteins were mainly involved in ER stress response, which was evidenced by the expression of ER stress marker proteins, HSP90, Bip and PDI. Moreover, we found that JB provoked the generation of reactive oxygen species (ROS), and that inhibition of the ROS generation with N-acetyl L-cysteine could reverse the JB-induced apoptosis. Confocal microscopy and flow cytometry showed that JB treatment enhanced intracellular and mitochondrial Ca2+ level and JC-1 assay revealed a loss of mitochondrial membrane potential in CRC after JB treatment. The mitochondrial Ca2+ uptake and depolarization can be blocked by Ruthenium Red (RuRed), an inhibitor of mitochondrial Ca2+ uniporter. Taken together, we demonstrated that JB exerts its anticancer effect by ER stress-Ca2+-mitochondria signaling, suggesting the promising chemotherapeutic potential of JB for the treatment of CRC. PMID:29207638

Jolkinolide B induces apoptosis of colorectal carcinoma through ROS-ER stress-Ca2+-mitochondria dependent pathway.

PubMed

Zhang, Jing; Wang, Yang; Zhou, Ye; He, Qing-Yu

2017-10-31

Colorectal carcinoma (CRC) remains one of the leading causes of death in cancer-related diseases. In this study, we aimed to investigate the anticancer effect of Jolkinolide B (JB), a bioactive diterpenoid component isolated from the dried roots of Euphorbia fischeriana Steud, on CRC cells and its underlying mechanisms. We found that JB suppressed the cell viability and colony formation of CRC cells, HT29 and SW620. Annexin V/PI assay revealed that JB induced apoptosis in CRC cells, which was further confirmed by the increased expression of cleaved-caspase3 and cleaved-PARP. iTRAQ-based quantitative proteomics was performed to identify JB-regulated proteins in CRC cells. Gene Ontology (GO) analysis revealed that these JB-regulated proteins were mainly involved in ER stress response, which was evidenced by the expression of ER stress marker proteins, HSP90, Bip and PDI. Moreover, we found that JB provoked the generation of reactive oxygen species (ROS), and that inhibition of the ROS generation with N-acetyl L-cysteine could reverse the JB-induced apoptosis. Confocal microscopy and flow cytometry showed that JB treatment enhanced intracellular and mitochondrial Ca 2+ level and JC-1 assay revealed a loss of mitochondrial membrane potential in CRC after JB treatment. The mitochondrial Ca 2+ uptake and depolarization can be blocked by Ruthenium Red (RuRed), an inhibitor of mitochondrial Ca 2+ uniporter. Taken together, we demonstrated that JB exerts its anticancer effect by ER stress-Ca 2+ -mitochondria signaling, suggesting the promising chemotherapeutic potential of JB for the treatment of CRC.

The pleasures and perils of prophetic advocacy: Henry E. Sigerist and the politics of medical reform.

PubMed Central

Fee, E

1996-01-01

Henry E. Sigerist, an internationally renowned medical historian, played a surprisingly important and visible role in American medical politics in the 1930s and 1940s. Born in Paris of Swiss parents, he was professor in Leipzig, Germany, before coming to the United States in 1932 as professor of the history of medicine at Johns Hopkins University. Once in America. Sigerist became deeply involved in medical politics and the campaign for national health insurance. He argued that individualized medical practice was outdated and should gradually be superseded by state-run and state-financed health services. National health insurance was but one step in this historical progression. Sigerist thus lent the weight of history itself to the cause of medical care reform. The charming and erudite Sigerist was welcomed by the leaders of academic medicine in America. Soon, he emerged as a spokesman of the left wing of the medical profession, an effective and popular speaker and an impassioned advocate of socialized medicine. This paper traces Sigerist's political ideas and activities, and his contributions toward medical care reform in the United States. Images p1639-a p1642-a PMID:8916536

Henry Hollingsworth Smith and His Bibliographical Index and Historical Record: The Beginning of American Surgical Historiography.

PubMed

Rutkow, Ira

2016-04-01

To explore the details of Henry Hollingsworth Smith's (1815-1890) achievement as the first physician to organize in a systematic and chronologic manner the details of the history of surgery in America and prepare a register of men who performed surgical operations. The life of Smith, the earliest of the nation's surgeons to elucidate the history of American surgery, is little known. His boosting the image of the scalpel wielder helped shape the future of the craft, in particular, surgery's rise as a specialty and profession. An analysis of the published medical literature and unpublished documents relating to Smith and his work to document the history of American surgery. During the 1850 s, a time when surgery was not considered a separate branch of medicine but a mere technical mode of treatment, Smith's efforts in surgical history provided much needed encouragement to surgeons in their pursuit of professional recognition. Although Smith's accomplishment as the nation's first compiler of the history of American surgery has long been forgotten, his effort afforded the men who performed surgical operations their earliest measure of self-respect. As such, Smith belongs in America's pantheon of surgical heroes.

Inspiring engineering minds to advance human health: the Henry Samueli School of Engineering's Department of BME.

PubMed

Lee, Abraham; Wirtanen, Erik

2012-07-01

The growth of biomedical engineering at The Henry Samueli School of Engineering at the University of California, Irvine (UCI) has been rapid since the Center for Biomedical Engineering was first formed in 1998 [and was later renamed as the Department of Biomedical Engineering (BME) in 2002]. Our current mission statement, “Inspiring Engineering Minds to Advance Human Health,” serves as a reminder of why we exist, what we do, and the core principles that we value and by which we abide. BME exists to advance the state of human health via engineering innovation and practices. To attain our goal, we are empowering our faculty to inspire and mobilize our students to address health problems. We treasure the human being, particularly the human mind and health. We believe that BME is where minds are nurtured, challenged, and disciplined, and it is also where the health of the human is held as a core mission value that deserves our utmost priority (Figure 1). Advancing human health is not a theoretical practice; it requires bridging between disciplines (engineering and medicine) and between communities (academic and industry).

Joint bleeds in von Willebrand disease patients have significant impact on quality of life and joint integrity: a cross-sectional study.

PubMed

van Galen, K P M; Sanders, Y V; Vojinovic, U; Eikenboom, J; Cnossen, M H; Schutgens, R E G; van der Bom, J G; Fijnvandraat, K; Laros-Van Gorkom, B A P; Meijer, K; Leebeek, F W G; Mauser-Bunschoten, E P

2015-05-01

Joint bleeds (JB) are reported in a minority of patients with von Willebrand disease (VWD) but may lead to structural joint damage. Prevalence, severity and impact of JB in VWD are largely unknown. The aim of this study was to assess JB prevalence, onset, treatment and impact on health-related quality of life (HR-QoL) and joint integrity in moderate and severe VWD. In the Willebrand in the Netherlands study 804 moderate and severe VWD patients [von Willebrand factor (VWF) activity ≤30U dL(-1)] completed a questionnaire on occurrence, sites and consequences of JB. To analyse JB number, onset, treatment and impact on joint integrity we additionally performed a patient-control study on medical file data comparing patients with JB to age, gender, factor VIII (FVIII)- and VWF activity matched VWD patients without JB. Of all VWD patients 23% (184/804) self-reported JB. These 184 patients reported joint damage more often (54% vs. 18%, P < 0.001) and had lower HR-QoL (SF36, P < 0.05) compared to VWD patients not reporting JB. Of 55 patients with available JB data, 65% had the first JB before age 16. These 55 patients used more clotting factor concentrate (CFC; median dose 43 vs. 0 IE FVIII kg(-1) year(-1) , P < 0.001), more often had X-ray joint damage (44% vs. 11%, P = 0.001] and chronic joint pain (44% vs. 18%, P = 0.008) compared to 55 control VWD patients without JB. In conclusion, joint bleeds are reported by 23% of moderate and severe VWD patients, mostly start in childhood, are associated with more CFC use, joint pain, lower HR-QoL and significantly more radiological and self-reported joint damage. © 2015 John Wiley & Sons Ltd.

Jolkinolide B inhibits glycolysis by downregulating hexokinase 2 expression through inactivating the Akt/mTOR pathway in non-small cell lung cancer cells.

PubMed

Gao, Xiang; Han, Han

2018-06-01

Jolkinolide B (JB), a bioactive compound isolated from herbal medicine, has been found to inhibit tumor growth by altering glycolysis. However, whether glycolysis is influenced by JB in non-small cell lung cancer (NSCLC) cells and the mechanism remain unknown. The aim of the present study was to evaluate the effect of JB on the glycolysis in NSCLC cells and the underlying molecular mechanism. The results showed that JB treatment inhibited cell viability of A549 and H1299 cells in a concentration-dependent manner. JB reduced the glucose consumption, lactate production, and HK2 expression. The expressions of p-Akt and p-mTOR were also decreased by JB treatment. Knockdown of HK2 reduced glucose consumption and lactate production. Inhibition of the Akt/mTOR pathway decreased HK2 expression and inhibited glycolysis. In conclusion, the results indicated that JB inhibits glycolysis by down-regulating HK2 expression through inactivating the Akt/mTOR pathway in NSCLC cells, suggesting that JB might be a potential therapeutic agent for the treatment of NSCLC. © 2018 Wiley Periodicals, Inc.

In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B.

PubMed

Qazzaz, Mohannad E; Raja, Vijay J; Lim, Kuan-Hon; Kam, Toh-Seok; Lee, Jong Bong; Gershkovich, Pavel; Bradshaw, Tracey D

2016-01-28

Natural products play a pivotal role in medicine especially in the cancer arena. Many drugs that are currently used in cancer chemotherapy originated from or were inspired by nature. Jerantinine B (JB) is one of seven novel Aspidosperma indole alkaloids isolated from the leaf extract of Tabernaemontana corymbosa. Preliminary antiproliferative assays revealed that JB and JB acetate significantly inhibited growth and colony formation, accompanied by time- and dose-dependent apoptosis induction in human cancer cell lines. JB significantly arrested cells at the G2/M cell cycle phase, potently inhibiting tubulin polymerisation. Polo-like kinase 1 (PLK1; an early trigger for the G2/M transition) was also dose-dependently inhibited by JB (IC50 1.5 µM). Furthermore, JB provoked significant increases in reactive oxygen species (ROS). Annexin V+ cell populations, dose-dependent accumulation of cleaved-PARP and caspase 3/7 activation, and reduced Bcl-2 and Mcl-1 expression confirm apoptosis induction. Preclinical in silico biopharmaceutical assessment of JB calculated rapid absorption and bioavailability >70%. Doses of 8-16 mg/kg JB were predicted to maintain unbound plasma concentrations >GI50 values in mice during efficacy studies. These findings advocate continued development of JB as a potential chemotherapeutic agent. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

How Subjects Do not Store and Retrieve Information About Ordered Relationships.

ERIC Educational Resources Information Center

Potts, George R.

Subjects learned and answered questions about four- or six-term linear orderings (e.g., Tom is taller than Dick, who is taller than Sam, who is taller than Pete). Such an ordering is comprised of some adjacent pairwise relations that are necessary to the establishment of the ordering (e.g., Tom is taller than Dick, Dick is taller than Sam), and…

Protective effect of Jolkinolide B on LPS-induced mouse acute lung injury.

PubMed

Yang, Hailing; Li, Yan; Huo, Pengfei; Li, Xiao-Ou; Kong, Daliang; Mu, Wei; Fang, Wei; Li, Lingxia; Liu, Ning; Fang, Ling; Li, Hongjun; He, Chengyan

2015-05-01

Jolkinolide B (JB), an ent-abietane diterpenoid, isolated from the dried root of Euphorbia fischeriana, has been reported to have potent anti-tumor and anti-inflammatory activities. However, the effects of JB on acute lung injury (ALI) and underlying molecular mechanisms have not been investigated. The present study aimed to investigate the effect of JB on lipopolysaccharide (LPS)-induced ALI. Male C57BL/6 mice were pretreated with dexamethasone or JB 1h before intranasal instillation of LPS. The results showed that JB markedly attenuated LPS-induced histological alterations, lung edema, inflammatory cell infiltration, myeloperoxidase (MPO) activity as well as the production of TNF-α, IL-6 and IL-1β. Furthermore, JB also significantly inhibited LPS-induced the degradation of IκBα and phosphorylation of NF-κB p65 and MAPK. Therefore, our study provides the first line of evidence that pretreatment of JB has a protective effect on LPS-induced ALI in mice. The anti-inflammatory mechanism of JB may be attributed to its suppression of NF-κB and MAPK activation. Copyright © 2015 Elsevier B.V. All rights reserved.

Pioneers in infection control: John Snow, Henry Whitehead, the Broad Street pump, and the beginnings of geographical epidemiology.

PubMed

Newsom, S W B

2006-11-01

John Snow was one of the founders of epidemiology. Already convinced of the value of pure water, he analysed the distribution of cholera cases in the 1848 epidemic in relation to the purity of the water supply in London. His hypothesis that cholera was spread by contaminated water was tested by the 'Broad Street' epidemic of 1854. Snow quickly traced the water used in the houses affected by cholera to the pump in Broad Street, and persuaded the parish council to remove the handle. The epidemic subsided. The council did not really believe Snow, so the curate, Henry Whitehead, set out to repeat Snow's work, albeit at a more leisurely pace as the epidemic had subsided. He located 700 deaths within a 250-yard radius and showed that use of water from the Broad Street pump was strongly correlated with death from cholera. This surprised him as he had drunk water from the pump himself during the outbreak. Thus 'geographical epidemiology' began, although it was some years before Snow's observations were generally accepted.

Jolkinolide B induces apoptosis in MCF-7 cells through inhibition of the PI3K/Akt/mTOR signaling pathway.

PubMed

Xu, Hui-Yu; Chen, Zhi-Wei; Hou, Jin-Cai; Du, Feng-Xia; Liu, Ji-Cheng

2013-01-01

The aim of this study was to explore the molecular mechanisms of jolkinolide B (JB), which is extracted from the root of Euphorbia fischeriana Steud. In this study, we found that JB, a diterpenoid from the traditional Chinese medicinal herb, strongly inhibited the PI3K/Akt/mTOR signaling pathway. Furthermore, we evaluated the effects of JB on the proliferation and apoptosis of MCF-7 human breast cancer cells. Our results showed significant induction of apoptosis in MCF-7 cells incubated with JB. The viability of the MCF-7 cells was assessed by MTT assay. Flow cytometry was used to detect apoptosis and cell cycle analysis. Transmission electron microscopy (TEM) analysis was used to observe cell morphology. MCF-7 cells were subcutaneously inoculated into nude mice to study the in vivo antitumor effects of JB. The growth of MCF-7 cells was inhibited and arrested in the S phase by JB. The data showed significantly decreased tumor volume and weight in nude mice inoculated with MCF-7 cells. In addition, treatment with JB was able to induce downregulation of cyclinD1, cyclinE, mTOR, p-PI3K and p-Akt, and upregulation of PTEN and p-eIF4E. Collectively, JB-induced apoptosis of MCF-7 cells occurs through the PI3K/Akt/mTOR signaling pathway. Furthermore, the PI3K/Akt signaling cascade plays a role in the induction of apoptosis in JB-treated cells. These observations suggest that JB may have therapeutic applications in the treatment of cancer.

Recent advances in thermal desorption-gas chromatography-mass spectrometery method to eliminate the matrix effect between air and water samples: application to the accurate determination of Henry's law constant.

PubMed

Kim, Yong-Hyun; Kim, Ki-Hyun

2014-05-16

Accurate values for the Henry's law constants are essential to describe the environmental dynamics of a solute, but substantial errors are recognized in many reported data due to practical difficulties in measuring solubility and/or vapor pressure. Despite such awareness, validation of experimental approaches has scarcely been made. An experimental approach based on thermal desorption-gas chromatography-mass spectrometery (TD-GC-MS) method was developed to concurrently allow the accurate determination of target compounds from the headspace and aqueous samples in closed equilibrated system. The analysis of six aromatics and eight non-aromatic oxygenates was then carried out in a static headspace mode. An estimation of the potential bias and mass balance (i.e., sum of mass measured individually from gas and liquid phases vs. the mass initially added to the system) demonstrates compound-specific phase dependency so that the best results are obtained by aqueous (less soluble aromatics) and headspace analysis (more soluble non-aromatics). Accordingly, we were able to point to the possible sources of biases in previous studies and provide the best estimates for the Henry's constants (Matm(-1)): benzene (0.17), toluene (0.15), p-xylene (0.13), m-xylene (0.13), o-xylene (0.19), styrene (0.27); propionaldehyde (9.26), butyraldehyde (6.19), isovaleraldehyde (2.14), n-valeraldehyde (3.98), methyl ethyl ketone (10.5), methyl isobutyl ketone (3.93), n-butyl acetate (2.41), and isobutyl alcohol (22.2). Copyright © 2014 Elsevier B.V. All rights reserved.

Morphological and positional relationships between the sigmoid sinus and the jugular bulb.

PubMed

Dai, Pei-Dong; Zhang, Hong-Qi; Wang, Zheng-Min; Sha, Yan; Wang, Ke-Qiang; Zhang, Tian-Yu

2007-12-01

The purpose of this study was to determine the quantitative relationships between the positions of the sigmoid sinus (SS) and jugular bulb (JB) and the influence of mastoid pneumatization upon these structures. The investigations were carried out on 116 healthy adult ears based on the axial images of computed tomography (CT). The reference system locating the displacements of the SS and JB was established and the shape and position of the SS and JB were measured. The volume of pneumatization was quantitatively measured based on the serial digital images of CT. The method of partial correlation analysis was used to find the real relationship of two variables from the complicated dependence relationships. There was a tendency for the SS in the males to be situated more laterally and more backwardly, and the JB in the males was situated more laterally with thicker lateral bone wall when compared to the females. When compared to the left side, the SS on the right side tended to protrude more deeply and was situated more laterally and with less thickness of the lateral bone wall. In male, the right SS was situated more anteriorly than the left SS. In female, the right JB was situated more posteriorly than the left JB. There was a tendency for the SS to be situated more medially, to have a thicker lateral bone wall, and to protrude more superficially in the well-pneumatized bones. When the pneumatization was well, the JB tended to be situated more backwards and have a thicker lateral bone wall. However, there was no significant difference of pneumatization between the high JB group and the low JB group. The SS position and JB position changed synchronously in forward-backward or medial-lateral directions. The results suggest that the factors that influence the shape and position of the SS and JB are multiple. The results suggest that the morphological and positional relationships between the SS and the JB are complicated but could be grasped. The development of the

Oestrogen and progesterone receptor assays in breast tumours. The Prince Henry's Hospital experience, 1983-1990.

PubMed

Pearce, P T; Myles, K M; Funder, J W

1993-08-16

To present and analyse the results of eight years of experience (1983-1990) in breast tumour receptor analysis. All female primary breast tumour samples received (4683) were analysed for seasonal variation, patient age, relative risk index, oestrogen receptor (ER) and progesterone receptor (PR) status, ER and PR status as a function of age, ER and PR levels as a function of age, and ER and PR levels as a function of month of analysis. The assays were done at the Medical Research Centre, Prince Henry's Hospital, Melbourne, as a non-profit service to surgeons, oncologists and pathologists. The numbers of samples referred for assay increased progressively each year, from 473 in 1983 to 1097 in 1990, but the receptor status (ER +/-, PR +/-) appeared not to vary from year to year. ER+PR+ tumours were the most common in all age groups, steadily increasing from between 50% and 60% in premenopausal women to 70% or more in those aged over 80. In postmenopausal women, levels of ER in ER+ tumours were three times those in premenopausal women; PR levels in PR+ tumours, however, were bimodal, with higher levels in the age groups 35-49 and 70-89 years than in women aged 50-69 years. No significant seasonal variation was seen, and the overall patterns of receptor status are similar to those seen in Northern hemisphere studies.

Application of a BOSS-Gaussian interface for QM/MM simulations of Henry and methyl transfer reactions.

PubMed

Vilseck, Jonah Z; Kostal, Jakub; Tirado-Rives, Julian; Jorgensen, William L

2015-10-15

Hybrid quantum mechanics and molecular mechanics (QM/MM) computer simulations have become an indispensable tool for studying chemical and biological phenomena for systems too large to treat with QM alone. For several decades, semiempirical QM methods have been used in QM/MM simulations. However, with increased computational resources, the introduction of ab initio and density function methods into on-the-fly QM/MM simulations is being increasingly preferred. This adaptation can be accomplished with a program interface that tethers independent QM and MM software packages. This report introduces such an interface for the BOSS and Gaussian programs, featuring modification of BOSS to request QM energies and partial atomic charges from Gaussian. A customizable C-shell linker script facilitates the interprogram communication. The BOSS-Gaussian interface also provides convenient access to Charge Model 5 (CM5) partial atomic charges for multiple purposes including QM/MM studies of reactions. In this report, the BOSS-Gaussian interface is applied to a nitroaldol (Henry) reaction and two methyl transfer reactions in aqueous solution. Improved agreement with experiment is found by determining free-energy surfaces with MP2/CM5 QM/MM simulations than previously reported investigations using semiempirical methods. © 2015 Wiley Periodicals, Inc.

Daily Management System of the Henry Ford Production System: QTIPS to Focus Continuous Improvements at the Level of the Work.

PubMed

Zarbo, Richard J; Varney, Ruan C; Copeland, Jacqueline R; D'Angelo, Rita; Sharma, Gaurav

2015-07-01

To support our Lean culture of continuous improvement, we implemented a daily management system designed so critical metrics of operational success were the focus of local teams to drive improvements. We innovated a standardized visual daily management board composed of metric categories of Quality, Time, Inventory, Productivity, and Safety (QTIPS); frequency trending; root cause analysis; corrective/preventive actions; and resulting process improvements. In 1 year (June 2013 to July 2014), eight laboratory sections at Henry Ford Hospital employed 64 unique daily metrics. Most assessed long-term (>6 months), monitored process stability, while short-term metrics (1-6 months) were retired after successful targeted problem resolution. Daily monitoring resulted in 42 process improvements. Daily management is the key business accountability subsystem that enabled our culture of continuous improvement to function more efficiently at the managerial level in a visible manner by reviewing and acting based on data and root cause analysis. Copyright© by the American Society for Clinical Pathology.

Heinrich Dieter Holland (1927-2012)

NASA Astrophysics Data System (ADS)

Turekian, Karl K.

2012-08-01

Heinrich Dieter "Dick" Holland, who died on 21 May 2012, was responsible for major advances across several fields of geochemistry. He was born on 27 May 1927 and died just short of his 85th birthday. How Dick became a geochemist is an interesting story in itself. I first met Dick when we shared an office as graduate students at Columbia University in New York. He had attended Princeton University in New Jersey and graduated in 1946 with a chemistry major. He had arrived in the United States with his family from Germany in 1940. The family was of Jewish origin, and although Dick and his relatives were not strict practitioners, their fate in Hitler's Germany, dictated by the family's ancestry, would have been undesirable. Dick and his brother first went to England in 1939 to escape the future horrors that were sure to await them if they had remained in Germany. After their parents escaped to the Dominican Republic, Dick and his brother joined them there. With the help of friends, the family came to the United States from the Dominican Republic in 1940 (it was not unusual for immigrants to first come to a landing spot in the western hemisphere prior to admission to the United States).

Comparison of the peripheral blood leukocyte population between Japanese Black and Holstein calves.

PubMed

Ohtsuka, Hiromichi; Ono, Maiko; Saruyama, Yumi; Mukai, Machiko; Kohiruimaki, Masayuki; Kawamura, Seiichi

2011-02-01

Japanese black (JB) calves have greater susceptibility to infectious diseases compared to Holstein (Hol) calves. In order to clarify the differences in cellular immune status between JB and Hol calves, the leukocyte population and lymphocyte proliferative ability were analyzed. In total 200 healthy calves, 1 day to 14 weeks of age, were examined: 105 JB and 95 Hol calves. Lower numbers in peripheral blood and percentage in peripheral blood mononuclear cells of CD3(+)TcR1-N12(+) T cells and major histocompatibility complex class-II(+)CD14(-) B cells were observed in the JB compared to the Hol. The percentage of TcR1-N12(+)CD25(+) T cell in the JB was significantly lower than that of the Hol at 4-6, and 8-10 weeks. Interleukin (IL)-2 sensitivity in the JB was lower than that in the Hol, and significant differences were observed in age groups of 6-8 weeks and 10-14 weeks. These findings indicated that the lower numbers of γδ T cells and B cells in the JB compared to the Hol might be associated with the specificity of the immune systems in JB calves. © 2011 The Authors. Journal compilation © 2011 Japanese Society of Animal Science.

Impact of insecticide-manipulated defoliation by Japanese beetle (Popillia japonica) on grapevines from vineyard establishment through production.

PubMed

Hammons, Derrick L; Kaan Kurtural, S; Potter, Daniel A

2010-05-01

Japanese beetle (JB), Popillia japonica Newman, is a severe pest of grapes in the southeastern USA where viticulture is a growing industry. This study evaluated the impact of foliar injury from JB field populations on growth, fruit ripening, berry composition and yield of young vines of six cultivars from vineyard establishment through the first year of production. Three spray regimes, carbaryl applied every 7 or 14 days, or no insecticide, were used to manipulate levels of defoliation by JB. Cultivars varied in susceptibility and response to defoliation by JB. Some (e.g. Norton) showed reduced vine growth and delayed post-veraison increase in total soluble sugars and pH, as well as reduced cluster number and weight, berries per cluster and yield. Others (e.g. Concord) showed little or no measurable impact from JB. Notably, the biweekly spray regime was as effective as weekly sprays in mitigating the impacts of defoliation. Foliar loss from JB feeding can set back establishment and productivity of young grapevines. Nevertheless, many growers can reduce spray frequency without compromising the benefits of JB management. Even susceptible cultivars can tolerate low to moderate (<20%) levels of defoliation, and some are resistant enough to be grown without treating for JB.

[The materialistic strategy of Henry Howard, a Québec alienist (1815-1887).].

PubMed

Fugère, A

1978-01-01

At the end of the 19th century, Henry Howard appeared as the first Quebec "aliéniste" to attempt to develop an inclusive theoretical treatise on the question of madness. Why this sudden upheaval ? There existed numerous european theories ; that might have sufficed. The author attempts to show the multiple connections of this theoretical pro-lect to the socio-political problems of québécois society. Howard tries, from the perspective of the theory which he elaborates, to intervene in the major discussions affecting Quebec: ultra montanism, the problem of universal compusory education, public morality. At a more professional level he attempts to intervene in the legal dispute opposing judicial and medical competence in the cases of insanity pleas, as well as in the question of the scientific and social status of the "aliéniste". The involvement in these struggles manifests itself in Howard's treatise as much at the level of the concepts themselves, and their architecture, as at the thematic level and in the applications which he naturally draws. It is not onty external and contingent but works on the text from the inside as well. The article attempts to suggest that at the very moment that the treatise on the alienated-which would become the "science" that we know today- seeks to structure itself into a theory, it cannot break its attachment to its determining social context and that, ignoring its ideological role it, in truth, succeeds only in creating illusion and the impression of a progressive process, all the while being circumstantial and having a verted interest.

Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects.

PubMed

Kelly, John R; Allen, Andrew P; Temko, Andriy; Hutch, William; Kennedy, Paul J; Farid, Niloufar; Murphy, Eileen; Boylan, Geraldine; Bienenstock, John; Cryan, John F; Clarke, Gerard; Dinan, Timothy G

2017-03-01

Preclinical studies have identified certain probiotics as psychobiotics - live microorganisms with a potential mental health benefit. Lactobacillus rhamnosus (JB-1) has been shown to reduce stress-related behaviour, corticosterone release and alter central expression of GABA receptors in an anxious mouse strain. However, it is unclear if this single putative psychobiotic strain has psychotropic activity in humans. Consequently, we aimed to examine if these promising preclinical findings could be translated to healthy human volunteers. To determine the impact of L. rhamnosus on stress-related behaviours, physiology, inflammatory response, cognitive performance and brain activity patterns in healthy male participants. An 8week, randomized, placebo-controlled, cross-over design was employed. Twenty-nine healthy male volunteers participated. Participants completed self-report stress measures, cognitive assessments and resting electroencephalography (EEG). Plasma IL10, IL1β, IL6, IL8 and TNFα levels and whole blood Toll-like 4 (TLR-4) agonist-induced cytokine release were determined by multiplex ELISA. Salivary cortisol was determined by ELISA and subjective stress measures were assessed before, during and after a socially evaluated cold pressor test (SECPT). There was no overall effect of probiotic treatment on measures of mood, anxiety, stress or sleep quality and no significant effect of probiotic over placebo on subjective stress measures, or the HPA response to the SECPT. Visuospatial memory performance, attention switching, rapid visual information processing, emotion recognition and associated EEG measures did not show improvement over placebo. No significant anti-inflammatory effects were seen as assessed by basal and stimulated cytokine levels. L. rhamnosus was not superior to placebo in modifying stress-related measures, HPA response, inflammation or cognitive performance in healthy male participants. These findings highlight the challenges associated with

Junctional bradycardia is a potential risk factor of stroke.

PubMed

Kim, Gwang Sil; Uhm, Jae-Sun; Kim, Tae-Hoon; Lee, Hancheol; Park, Junbeom; Park, Jin-Kyu; Joung, Boyoung; Pak, Hui-Nam; Lee, Moon-Hyoung

2016-07-25

This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB). We retrospectively reviewed electrocardiograms(ECGs) for 380,682 patients. Those with JB on an ECG at least twice over a ≥3-month interval were included for analysis. We additionally included 138 CHADS2 score-matched patients(age, 68.4 ± 15.7 years; male, 52.2%) in sinus rhythm as a control group. Between the JB patients(with or without retrograde P wave) and controls, we compared incidences of ischemic stroke and a composite of ischemic stroke, renal infarction, ischemic colitis, acute limb ischemia, and pulmonary embolism. Among 380,682 patients (age, 47.6 ± 19.9 years; male, 49.3%), 69 patients (age, 68.5 ± 16.5 years; male, 50.7%) exhibited JB on an ECG at least twice over a ≥3-month interval; the overall prevalence of JB was 0.02%. The mean follow-up period was 27.2 ± 26.2 months. Forty-five patients (65.2%) in the JB group had no retrograde P wave. Ischemic stroke incidence was significantly higher in JB patients without a retrograde P wave than in controls (6/45 patients [13.3%] and 3/138 patients [2.2%], respectively; P = 0.007). The incidence of composite thromboembolic events was also significantly higher in JB patients without a retrograde P wave than in controls (8/45 patients [17.8%] and 4/138 patients [2.9%], respectively; P = 0.011). In a Cox proportional hazards model, JB patients without a P wave showed a greater incidence of stroke (hazard ratio, 8.89 [2.20-33.01], P = 0.007) than controls and JB patients with a P wave. Junctional bradycardia is potentially associated with ischemic stroke, particularly in the absence of an identifiable retrograde P wave.

Temperature monitoring during cardiopulmonary bypass--do we undercool or overheat the brain?

PubMed

Kaukuntla, Hemanth; Harrington, Deborah; Bilkoo, Inderaj; Clutton-Brock, Tom; Jones, Timothy; Bonser, Robert S

2004-09-01

Brain cooling is an essential component of aortic surgery requiring circulatory arrest and inadequate cooling may lead to brain injury. Similarly, brain hyperthermia during the rewarming phase of cardiopulmonary bypass may also lead to neurological injury. Conventional temperature monitoring sites may not reflect the core brain temperature (Tdegrees). We compared jugular bulb venous temperatures (JB) during deep hypothermic circulatory arrest and normothermic bypass with Nasopharyngeal (NP), Arterial inflow (AI), Oesophageal (O), Venous return (VR), Bladder (B) and Orbital skin (OS) temperatures. 18 patients undergoing deep hypothermia (DH) and 8 patients undergoing normothermic bypass (mean bladder Tdegrees-36.29 degreesC) were studied. For DH, cooling was continued to 15 degreesC NP (mean cooling time-66 min). At pre-determined arterial inflow Tdegrees, NP, JB and O Tdegree's were measured. A 6-channel recorder continuously recorded all Tdegree's using calibrated thermocouples. During the cooling phase of DH, NP lagged behind AI and JB Tdegree's. All these equilibrated at 15 degreesC. During rewarming, JB and NP lagged behind AI and JB was higher than NP at any time point. During normothermic bypass, although NP was reflective of the AI and JB Tdegrees trends, it underestimated peak JB Tdegrees (P=0.001). Towards the end of bypass, peak JB was greater than the arterial inflow Tdegrees (P=0.023). If brain venous outflow Tdegrees (JB) accurately reflects brain Tdegrees, NP Tdegrees is a safe surrogate indicator of cooling. During rewarming, all peripheral sites underestimate brain temperature and caution is required to avoid hyperthermic arterial inflow, which may inadvertently, result in brain hyperthermia.

Simulating superradiance from higher-order-intensity-correlation measurements: Single atoms

NASA Astrophysics Data System (ADS)

Wiegner, R.; Oppel, S.; Bhatti, D.; von Zanthier, J.; Agarwal, G. S.

2015-09-01

Superradiance typically requires preparation of atoms in highly entangled multiparticle states, the so-called Dicke states. In this paper we discuss an alternative route where we prepare such states from initially uncorrelated atoms by a measurement process. By measuring higher-order intensity-intensity correlations we demonstrate that we can simulate the emission characteristics of Dicke superradiance by starting with atoms in the fully excited state. We describe the essence of the scheme by first investigating two excited atoms. Here we demonstrate how via Hanbury Brown and Twiss type of measurements we can produce Dicke superradiance and subradiance displayed commonly with two atoms in the single excited symmetric and antisymmetric Dicke states, respectively. We thereafter generalize the scheme to arbitrary numbers of atoms and detectors, and explain in detail the mechanism which leads to this result. The approach shows that the Hanbury Brown and Twiss type of intensity interference and the phenomenon of Dicke superradiance can be regarded as two sides of the same coin. We also present a compact result for the characteristic functional which generates all order intensity-intensity correlations.

Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase.

PubMed

Cingolani, Francesca; Simbari, Fabio; Abad, Jose Luis; Casasampere, Mireia; Fabrias, Gemma; Futerman, Anthony H; Casas, Josefina

2017-08-01

Sphingolipids (SLs) have been extensively investigated in biomedical research due to their role as bioactive molecules in cells. Here, we describe the effect of a SL analog, jaspine B (JB), a cyclic anhydrophytosphingosine found in marine sponges, on the gastric cancer cell line, HGC-27. JB induced alterations in the sphingolipidome, mainly the accumulation of dihydrosphingosine, sphingosine, and their phosphorylated forms due to inhibition of ceramide synthases. Moreover, JB provoked atypical cell death in HGC-27 cells, characterized by the formation of cytoplasmic vacuoles in a time and dose-dependent manner. Vacuoles appeared to originate from macropinocytosis and triggered cytoplasmic disruption. The pan-caspase inhibitor, z-VAD, did not alter either cytotoxicity or vacuole formation, suggesting that JB activates a caspase-independent cell death mechanism. The autophagy inhibitor, wortmannin, did not decrease JB-stimulated LC3-II accumulation. In addition, cell vacuolation induced by JB was characterized by single-membrane vacuoles, which are different from double-membrane autophagosomes. These findings suggest that JB-induced cell vacuolation is not related to autophagy and it is also independent of its action on SL metabolism. Copyright © 2017 by the American Society for Biochemistry and Molecular Biology, Inc.

Jolkinolide B induces apoptosis in MDA-MB-231 cells through inhibition of the PI3K/Akt signaling pathway.

PubMed

Lin, Yu; Cui, Hongxia; Xu, Huiyu; Yue, Liling; Xu, Hao; Jiang, Liyan; Liu, Jicheng

2012-06-01

The phosphoinositol-3-kinase (PI3K)/Akt signal transduction pathway is critically important for tumor cell growth, proliferation and apoptosis. Apoptosis activation has been reported to be a good target in cancer therapies. In this study, we have found that jolkinolide B (JB), a diterpenoid from the traditional Chinese medicinal herb Euphorbia fischeriana Steud, strongly inhibited the expression of the PI3K p85 subunit and the phosphorylation of Akt. Furthermore, we evaluated the effects of JB on the proliferation and apoptosis of MDA-MB-231 human breast cancer cells. Our results show significant induction of apoptosis in MDA-MB-231 cells incubated with JB. This effect was enhanced by combination with LY294002. In addition, treatment with JB could induce downregulation of the Bcl-2/Bax ratio, and subsequent promotion of mitochondrial release of cytochrome c and activation of caspase-3. Taken together, JB-induced apoptosis of MDA-MB-231 cells occurs through the mitochondrial pathway. Further, the PI3K/Akt signaling cascade plays a role in the induction of apoptosis in JB-treated cells. These observations suggest that JB may have therapeutic applications in the treatment of cancer.

Optimal experimental designs for estimating Henry's law constants via the method of phase ratio variation.

PubMed

Kapelner, Adam; Krieger, Abba; Blanford, William J

2016-10-14

When measuring Henry's law constants (k H ) using the phase ratio variation (PRV) method via headspace gas chromatography (G C ), the value of k H of the compound under investigation is calculated from the ratio of the slope to the intercept of a linear regression of the inverse G C response versus the ratio of gas to liquid volumes of a series of vials drawn from the same parent solution. Thus, an experimenter collects measurements consisting of the independent variable (the gas/liquid volume ratio) and dependent variable (the G C -1 peak area). A review of the literature found that the common design is a simple uniform spacing of liquid volumes. We present an optimal experimental design which estimates k H with minimum error and provides multiple means for building confidence intervals for such estimates. We illustrate performance improvements of our design with an example measuring the k H for Naphthalene in aqueous solution as well as simulations on previous studies. Our designs are most applicable after a trial run defines the linear G C response and the linear phase ratio to the G C -1 region (where the PRV method is suitable) after which a practitioner can collect measurements in bulk. The designs can be easily computed using our open source software optDesignSlopeInt, an R package on CRAN. Copyright © 2016 Elsevier B.V. All rights reserved.

Application of a BOSS – Gaussian Interface for QM/MM Simulations of Henry and Methyl Transfer Reactions

PubMed Central

Vilseck, Jonah Z.; Kostal, Jakub; Tirado-Rives, Julian; Jorgensen, William L.

2015-01-01

Hybrid quantum mechanics and molecular mechanics (QM/MM) computer simulations have become an indispensable tool for studying chemical and biological phenomena for systems too large to treat with quantum mechanics alone. For several decades, semi-empirical QM methods have been used in QM/MM simulations. However, with increased computational resources, the introduction of ab initio and density function methods into on-the-fly QM/MM simulations is being increasingly preferred. This adaptation can be accomplished with a program interface that tethers independent QM and MM software packages. This report introduces such an interface for the BOSS and Gaussian programs, featuring modification of BOSS to request QM energies and partial atomic charges from Gaussian. A customizable C-shell linker script facilitates the inter-program communication. The BOSS–Gaussian interface also provides convenient access to Charge Model 5 (CM5) partial atomic charges for multiple purposes including QM/MM studies of reactions. In this report, the BOSS–Gaussian interface is applied to a nitroaldol (Henry) reaction and two methyl transfer reactions in aqueous solution. Improved agreement with experiment is found by determining free-energy surfaces with MP2/CM5 QM/MM simulations than previously reported investigations employing semiempirical methods. PMID:26311531

Memorising Milton's Paradise lost: a study of a septuagenarian exceptional memoriser.

PubMed

Seamon, John G; Punjabi, Paawan V; Busch, Emily A

2010-07-01

At age 58, JB began memorising Milton's epic poem Paradise Lost. Nine years and thousands of study hours later, he completed this process in 2001 and recalled from memory all 12 books of this 10,565-line poem over a 3-day period. Now 74, JB continues to recite this work. We tested his memory accuracy by cueing his recall with two lines from the beginning or middle of each book and asking JB to recall the next 10 lines. JB is an exceptional memoriser of Milton, both in our laboratory tests in which he did not know the specific tests or procedures in advance, and in our analysis of a videotaped, prepared performance. Consistent with deliberate practice theory, JB achieved this remarkable ability by deeply analysing the poem's structure and meaning over lengthy repetitions. Our findings suggest that exceptional memorisers such as JB are made, not born, and that cognitive expertise can be demonstrated even in later adulthood.

Smog chamber experiments to investigate Henry's law constants of glyoxal using different seed aerosols as well as imidazole formation in the presence of ammonia

NASA Astrophysics Data System (ADS)

Jakob, Ronit

2015-04-01

Aerosols play an important role in the chemistry and physics of the atmosphere. Hence, they have a direct as well as an indirect impact on the earth's climate. Depending on their formation, one distinguishes between primary and secondary aerosols[1]. Important groups within the secondary aerosols are the secondary organic aerosols (SOAs). In order to improve predictions about these impacts on the earth's climate the existing models need to be optimized, because they still underestimate SOA formation[2]. Glyoxal, the smallest α-dicarbonyl, not only acts as a tracer for SOA formation but also as a direct contributor to SOA. Because glyoxal has such a high vapour pressure, it was common knowledge that it does not take part in gas-particle partitioning and therefore has no impact on direct SOA formation. However, the Henry's law constant for glyoxal is surprisingly high. This has been explained by the hydration of the aldehyde groups, which means that a species with a lower vapour pressure is produced. Therefore the distribution of glyoxal between gas- and particle phase is atmospherically relevant and the direct contribution of glyoxal to SOA can no longer be neglected[3]. Besides this particulate glyoxal is able to undergo heterogeneous chemistry with gaseous ammonia to form imidazoles. This plays an important role for regions with aerosols exhibiting alkaline pH values for example from lifestock or soil dust because imidazoles as nitrogen containing compounds change the optical properties of aerosols[4]. A high salt concentration present in chamber seed aerosols leads to an enhanced glyoxal uptake into the particle. This effect is called "salting-in". The salting effect depends on the composition of the seed aerosol as well as the soluble compound. For very polar compounds, like glyoxal, a "salting-in" is observed[3]. Glyoxal particle formation during a smog chamber campaign at Paul-Scherrer-Institut (PSI) in Switzerland was examined using different seed aerosols

Reinvestigation of the Henry's law constant for hydrogen peroxide with temperature and acidity variation.

PubMed

Huang, Daoming; Chen, Zhongming

2010-01-01

Hydrogen peroxide is not only an important oxidant in itself; it also serves as both sink and temporary reservoir for other important oxidants including HOx (OH and HO2) radicals and O3 in the atmosphere. Its partitioning between gas and aqueous phases in the atmosphere, usually described by its Henry's law constant (K(H)), significantly influences its role in atmospheric processes. Large discrepancies between the K(H) values reported in previous work, however, have created uncertainty for atmospheric modelers. Based on our newly developed online instrumentation, we have re-determined the temperature and acidity dependence of K(H) for hydrogen peroxide at an air pressure of (0.960 +/- 0.013) atm (1 atm = 1.01325 x 10(5) Pa). The results indicated that the temperature dependence of K(H) for hydrogen peroxide fits to the Van't Hoff equation form, expressed as lnK(H) = a/T - b, and a = -deltaH/R, where K(H) is in M/atm (M is mol/L), T is in degrees Kelvin, R is the ideal gas constant, and deltaH is the standard heat of solution. For acidity dependence, results demonstrated that the K(H) value of hydrogen peroxide appeared to have no obvious dependence on decreasing pH level (from pH 7 to pH 1). Combining the dependence of both temperature and acidity, the obtained a and b were 7024 +/- 138 and 11.97 +/- 0.48, respectively, deltaH was (58.40 +/- 1.15) kJ/(K x mol), and the uncertainties represent sigma. Our determined K(H) values for hydrogen peroxide will therefore be of great use in atmospheric models.

Effect of Jobelyn® on intruder- and isolation-induced aggressive behavior in mice.

PubMed

Umukoro, Solomon; Omogbiya, Itivere Adrian; Eduviere, Taghogho Anthony

2013-01-01

Aggression is a violent behavior emitted against another organism that may lead to its harm or death and thus is of public health significance, which necessitates the search for agents with anti-aggressive property. This study investigated the effect of Jobelyn® (JB), a unique African polyherbal formulation, on intruder- and isolation-induced aggressive behaviors in mice. Male mice that showed aggression after being housed individually with female counterparts for 3 weeks or kept in isolation for 4 weeks were treated orally (p.o.) with JB (5, 10 or 50 mg/kg), haloperidol (HP) (1 mg/kg), fluoxetine (FL) (10 mg/kg), p-chlorophenylalanine (PCPA) (20 mg/kg), mianserin (MS) (50 mg/kg) or distilled water (10 mL/kg) 60 min before being tested for aggression. Interaction studies involving oral administration of PCPA (20 mg/kg), FL (10 mg/kg) or MS (50 mg/kg) to aggressive mice that had received JB (5 or 10 mg/kg, p.o.) 30 min earlier were assessed. The effect of JB (5, 10 or 50 mg/kg, p.o.) on defensive behaviors was also evaluated. JB (5, 10 or 50 mg/kg) decreased aggressive behaviors without impairing the defensive mechanisms of mice. PCPA (20 mg/kg), an inhibitor of 5-hydroxytryptamine (5-HT) biosynthesis, increased aggressive responses and reduced the anti-aggressive effect of JB. FL (10 mg/kg), a 5-HT reuptake inhibitor, significantly suppressed aggression but did not alter the effect of JB on aggression. MS (50 mg/kg), a 5-HT receptor antagonist, reduced aggression and enhanced the effect of JB on aggression. These findings suggest that JB has anti-aggressive activity, which may be related to the enhancement of serotonergic system.

Jungermannenone A and B induce ROS- and cell cycle-dependent apoptosis in prostate cancer cells in vitro

PubMed Central

Guo, Yan-xia; Lin, Zhao-min; Wang, Mei-juan; Dong, Yi-wen; Niu, Huan-min; Young, Charles YF; Lou, Hong-xiang; Yuan, Hui-qing

2016-01-01

Aim: Jungermannenone A and B (JA, JB) are new ent-kaurane diterpenoids isolated from Chinese liverwort Jungermannia fauriana, which show anti-proliferation activities in cancer cells. In this study we investigated the mechanisms underlying the anticancer action of JA and JB in PC3 human prostate cancer cells in vitro. Methods: A panel of 9 human cancer cell lines was tested. Cell proliferation was assessed with a real-time cell analyzer and MTT assay. Cell apoptosis, cell cycle distribution and ROS levels were measured using cytometry. Mitochondrial damage was examined by transmission electron microscopy. DNA damage was detected with comet assay. Apoptotic, DNA damage- and cell cycle-related proteins were analyzed using Western blotting. The expression of DNA repair genes was measured with qRT-PCR. Results: Both JA and JB exerted potent anti-proliferative action against the 9 cancer cell lines, and PC3 cells were more sensitive with IC50 values of 1.34±0.09 and 4.93±0.20 μmol/L, respectively. JA (1.5 μmol/L) and JB (5 μmol/L) induced PC3 cell apoptosis, which was attenuated by the caspase inhibitor Z-VAD. Furthermore, both JA and JB caused mitochondrial damage and ROS accumulation in PC3 cells, whereas vitamin C blocked the ROS accumulation and attenuated the cytotoxicity of JA and JB. Moreover, both JA and JB induced DNA damage, accompanied by downregulated DNA repair proteins Ku70/Ku80 and RDA51. JA induced marked cell cycle arrest at the G0/G1 phase, which was related to c-Myc suppression, whereas JB enforced the cell cycle blockade in the G2/M phase, which associated with activation of the JNK signaling. Conclusion: Both JA and JB induce prostate cancer apoptosis via ROS accumulation and induction of cell cycle arrest. PMID:27133304

Jungermannenone A and B induce ROS- and cell cycle-dependent apoptosis in prostate cancer cells in vitro.

PubMed

Guo, Yan-Xia; Lin, Zhao-Min; Wang, Mei-Juan; Dong, Yi-Wen; Niu, Huan-Min; Young, Charles Yf; Lou, Hong-Xiang; Yuan, Hui-Qing

2016-06-01

Jungermannenone A and B (JA, JB) are new ent-kaurane diterpenoids isolated from Chinese liverwort Jungermannia fauriana, which show anti-proliferation activities in cancer cells. In this study we investigated the mechanisms underlying the anticancer action of JA and JB in PC3 human prostate cancer cells in vitro. A panel of 9 human cancer cell lines was tested. Cell proliferation was assessed with a real-time cell analyzer and MTT assay. Cell apoptosis, cell cycle distribution and ROS levels were measured using cytometry. Mitochondrial damage was examined by transmission electron microscopy. DNA damage was detected with comet assay. Apoptotic, DNA damage- and cell cycle-related proteins were analyzed using Western blotting. The expression of DNA repair genes was measured with qRT-PCR. Both JA and JB exerted potent anti-proliferative action against the 9 cancer cell lines, and PC3 cells were more sensitive with IC50 values of 1.34±0.09 and 4.93±0.20 μmol/L, respectively. JA (1.5 μmol/L) and JB (5 μmol/L) induced PC3 cell apoptosis, which was attenuated by the caspase inhibitor Z-VAD. Furthermore, both JA and JB caused mitochondrial damage and ROS accumulation in PC3 cells, whereas vitamin C blocked the ROS accumulation and attenuated the cytotoxicity of JA and JB. Moreover, both JA and JB induced DNA damage, accompanied by downregulated DNA repair proteins Ku70/Ku80 and RDA51. JA induced marked cell cycle arrest at the G0/G1 phase, which was related to c-Myc suppression, whereas JB enforced the cell cycle blockade in the G2/M phase, which associated with activation of the JNK signaling. Both JA and JB induce prostate cancer apoptosis via ROS accumulation and induction of cell cycle arrest.

[Tracing back for the basis. Research of Medieval medical manuscripts in Leipzig by Karl Sudhoff and Henry Ernest Sigerist].

PubMed

Löffler, Anette

2009-01-01

At the beginning of the 20th century, two known medical historians, Karl Sudhoff and Henry Ernst Sigerist, were among the first persons, who took up thorough investigations of medical manuscripts in Leipzig. Above all, it was Mr. Sudhoff, who developed his own procedure, in order to exploit the unknown stocks. Apart from the only means available to him, the so-called Leyser-papers, written by the Leipzig librarian Hermann Leyser, at least once Sudhoff made a complete check-up of all manuscripts over the period of 22 years. On 315 sheets he took down various more or less extensive notes regarding these Codices, which are kept today as manuscript collection (Ms 01269) in the library of the university of Leipzig. Many publications were written on the basis of these readings. Sigerist was only looking through a small number of Leipzig manuscripts, as could be seen from his remarks written onto the users' cards. However, he could rely on Sudhoff's notes and look for specific manuscripts that he was interested in and review them. This was a first and very important step for the investigation of Leipzig medical manuscripts.

Retrieval Strategies for Linearly Ordered Information

ERIC Educational Resources Information Center

Polich, John M.; Potts, George R.

1977-01-01

Subjects responded to pairs of test items from learned linear orderings (e.g., Tom is taller than Dick; Dick is taller than Sam, etc.). Results are compared with previous studies of ordered linguistic, perceptual, and numerical information. (Editor/RK)

Chronotropic Incompetence and Risk of Atrial Fibrillation: The Henry Ford ExercIse Testing (FIT) Project.

PubMed

O'Neal, Wesley T; Qureshi, Waqas T; Blaha, Michael J; Dardari, Zeina A; Ehrman, Jonathan K; Brawner, Clinton A; Soliman, Elsayed Z; Al-Mallah, Mouaz H

2016-11-01

To examine the association between chronotropic incompetence and incident atrial fibrillation (AF). Patients with inadequate heart rate response during exercise may have abnormalities in sinus node function or autonomic tone that predispose to the development of AF. We examined the association between heart rate response and incident AF in 57,402 (mean age=54±13 years, 47% female, 64% white) patients free of baseline AF who underwent exercise-treadmill stress testing from the Henry Ford ExercIse Testing (FIT) Project. Age-predicted maximum heart rate (pMHR) values <85% and chronotropic index values <80% were used to define chronotropic incompetence. Cox regression, adjusting for demographics, cardiovascular risk factors, medications, coronary heart disease, heart failure, and metabolic equivalent of task achieved, was used to compute hazard ratios (HR) and 95% confidence intervals (CI) for the association between chronotropic incompetence and incident AF. Over a median follow-up of 5.0 years (25 th -75 th percentiles=2.6, 7.8), a total of 3,395 (5.9%) participants developed AF. pMHR values <85% were associated with an increased risk for AF development (HR=1.33, 95%CI=1.22, 1.44). Chronotropic index values <80% also were associated with an increased risk of AF (HR=1.28, 95%CI=1.19, 1.38). The associations of pMHR and chronotropic index with AF remained significant with varying cut-off points to define chronotropic incompetence. Our analysis suggests that patients with inadequate heart rate response during exercise have an increased risk for developing AF.

Identification of leptin gene polymorphisms associated with carcass traits and fatty acid composition in Japanese Black cattle.

PubMed

Kawaguchi, Fuki; Okura, Kazuki; Oyama, Kenji; Mannen, Hideyuki; Sasazaki, Shinji

2017-03-01

Previous studies have indicated that some leptin gene polymorphisms were associated with economically important traits in cattle breeds. However, polymorphisms in the leptin gene have not been reported thus far in Japanese Black cattle. Here, we aimed to identify the leptin gene polymorphisms which are associated with carcass traits and fatty acid composition in Japanese Black cattle. We sequenced the full-length coding sequence of leptin gene for eight Japanese Black cattle. Sequence comparison revealed eight single nucleotide polymorphisms (SNPs). Three of these were predicted to cause amino acid substitutions: Y7F, R25C and A80V. Then, we genotyped these SNPs in two populations (JB1 with 560 animals and JB2 with 450 animals) and investigated the effects on the traits. Y7F in JB1 and A80V in JB2 were excluded from statistical analysis because the minor allele frequencies were low (< 0.1). Association analysis revealed that Y7F had a significant effect on the dressed carcass weight in JB2; R25C had a significant effect on C18:0 and C14:1 in JB1 and JB2, respectively; and A80V had a significant effect on C16:0, C16:1, C18:1, monounsaturated fatty acid and saturated fatty acid in JB1. The results suggested that these SNPs could be used as an effective marker for the improvement of Japanese Black cattle. © 2016 Japanese Society of Animal Science.

Jobelyn® pretreatment ameliorates symptoms of psychosis in experimental models.

PubMed

Omogbiya, Itivere Adrian; Umukoro, Solomon; Aderibigbe, Adegbuyi Oladele; Bakre, Adewale Ganiyu

2013-01-01

Psychosis is a chronic neurological disorder and it remains a major medical and social problem in most African countries. Individuals with psychotic illness in this region tend to seek help from traditional medical practitioners, who prescribe herbal remedies as alternative forms of treatment for the disease. Jobelyn® (JB) is a commercial polyherbal formulation that has been acclaimed to show beneficial effects in neurological disorders. However, its usefulness in psychosis has not been scientifically validated. Thus, this study was undertaken to evaluate its effects on animal models predictive of human psychosis. Antipsychotic activity of JB was assessed based on the inhibition of stereotyped behavior induced by amphetamine or apomorphine in mice. Amphetamine-induced hyperactivity and lethality in aggregated mice were additional tests employed to further evaluate the antipsychotic property of JB. The effect of JB on catalepsy was also assessed, using the inclined plane paradigm. JB (5-50 mg/kg, p.o.) significantly (p<0.05) inhibited stereotypy induced by amphetamine (10.0 mg/kg, i.p.) or apomorphine (1 mg/kg, i.p.), which suggests antipsychotic activity. Furthermore, JB (5-50 mg/kg, p.o.) reduced lethality in aggregated mice and inhibited hyperactivity induced by amphetamine, respectively. However, JB (5-50 mg/kg, p.o.) did not cause cataleptic behavior, as it failed to alter the duration of stay of the animals on the inclined plane. Taken together, these findings suggest that JB exhibits antipsychotic-like activity, devoid of the adverse effect of cataleptic behavior, and may offer some beneficial effects in the symptomatic relief of psychotic ailments.

Ft. McHenry tunnel study: Source profiles and mercury emissions from diesel and gasoline powered vehicles

NASA Astrophysics Data System (ADS)

Landis, Matthew S.; Lewis, Charles W.; Stevens, Robert K.; Keeler, Gerald J.; Dvonch, J. Timothy; Tremblay, Raphael T.

During the fall of 1998, the US Environmental Protection Agency and the Florida Department of Environmental Protection sponsored a 7-day study at the Ft. McHenry tunnel in Baltimore, MD with the objective of obtaining PM 2.5 vehicle source profiles for use in atmospheric mercury source apportionment studies. PM 2.5 emission profiles from gasoline and diesel powered vehicles were developed from analysis of trace elements, polycyclic aromatic hydrocarbons (PAH), and condensed aliphatic hydrocarbons. PM 2.5 samples were collected using commercially available sampling systems and were extracted and analyzed using conventional well-established methods. Both inorganic and organic profiles were sufficiently unique to mathematically discriminate the contributions from each source type using a chemical mass balance source apportionment approach. However, only the organic source profiles provided unique PAH tracers (e.g., fluoranthene, pyrene, and chrysene) for diesel combustion that could be used to identify source contributions generated using multivariate statistical receptor modeling approaches. In addition, the study found significant emission of gaseous elemental mercury (Hg 0), divalent reactive gaseous mercury (RGM), and particulate mercury (Hg(p)) from gasoline but not from diesel powered motor vehicles. Fuel analysis supported the tunnel measurement results showing that total mercury content in all grades of gasoline (284±108 ng L -1) was substantially higher than total mercury content in diesel fuel (62±37 ng L -1) collected contemporaneously at local Baltimore retailers.

Polarization properties of long-lived stimulated photon echo

NASA Astrophysics Data System (ADS)

Reshetov, V. A.; Popov, E. N.

2015-01-01

The polarization properties of the long-lived stimulated photon echo formed on the transition ja → jb with the atomic levels degenerate in the projections of the angular momenta are studied theoretically. The two particular transitions ja = 1 → jb = 0 and ja = 1 → jb = 1 with degenerate ground state ja = 1 are discussed. For the transitions ja = 1 → jb = 1 the polarizations and areas of the first (‘write’) and the third (‘read’) excitation pulses are found when the echo polarization faithfully reproduces the arbitrary polarization of the weak (single-photon) second (‘information’) pulse, so that this echo scheme may implement the quantum memory for a single-photon polarization qubit, while for the transitions ja = 1 → jb = 0 it is shown, that the echo polarization differs from that of the second pulse at any conditions.

Obituary: Richard B. Dunn, 1927-2005

NASA Astrophysics Data System (ADS)

Keil, Stephen L.; Dooling, David

2007-12-01

Dr. Richard B. Dunn, astronomer emeritus at the National Solar Observatory, died of a heart attack on September 29, 2005. He was recognized as one of the foremost experimental solar physicists. His innovative designs for telescopes and instruments led to many important discoveries in solar physics. Born in Baltimore, Maryland, in 1927 and raised in Minneapolis, Minnesota, Dick's parents were Dr. Halbert L. Dunn and Katherine Brandner. Halbert (MD, Ph.D., F.A.P.H.A.) was an physician who became Chief of the National Office of Vital Statistics, Public Health Service. He published a paper "High Level Wellness for Man and Society" that became the founding paper of the field of wellness health care. After their divorce in 1942, Katherine moved to New York and became a social worker. Dick had two older brothers who died before him, Halbert (born in 1921, who became a civil engineer) and Robert (born in 1924, who became an architect). Dick earned a BS in mechanical engineering and an MS in astronomy at the University of Minnesota. At the end of World War II he served in the United States Army in Japan. For his master's degree, Dick undertook the design and construction of a Lyot-type birefringent filter for observations of solar prominences. This early work led to his acceptance at Harvard, where Professor Donald Menzel encouraged him to continue his work with the 15-inch Cambridge telescope. In 1951 he conducted part of his doctoral thesis work at the fledgling Sacramento Peak Observatory in southern New Mexico. The observatory director, Dr. John Evans, was impressed with Dick's outstanding instrumental talents and invited him to join as one of the first scientific staff members. During his first few years at Sac Peak, Dick developed two more birefringent filter systems including one with an integrated coronagraph. With this system, he produced the best prominence and spicule observations ever obtained. Dick's career was dedicated to obtaining solar observations of the

Antioxidant Property of Jobelyn as the Possible Mechanism Underlying its Anti-amnesic Activity in Rodents.

PubMed

Umukoro, Solomon; Ugbomah, Adaeze; Aderibigbe, Adegbuyi; Omogbiya, Adrian

2013-01-01

Amnesia or loss of memory is the cardinal hallmark of Alzheimer's disease (AD), a progressive neurodegenerative disorder associated with ageing process. Although, AD had been discovered over a century ago, drugs which could cure or halt the progression of the disease are yet to see the light of the day. However, there has been a growing interest in the use of phytomedicines with multipronged mechanisms of action that could target various aspects of the pathologies of AD. Jobelyn (JB) is a potent antioxidant African polyherbal formulation with active components that have been acclaimed to show neuroprotection. This investigation was carried out to evaluate whether JB has anti-amnesic and antioxidant activities. The alteration of alternation behavior in the Y-maze paradigm was utilized as the test for memory function in mice. The effect of JB on acetylcholinesterase (AChE) activity, malondialdehyde (MDA) level and the concentrations of glutathione (GSH) in the frontal cortex and hippocampus were assessed in rats as means of providing insight into the mechanism underlying its anti-amnesic activity. The animals were given JB (1, 2.5 or 5mg/kg, i.p.) daily for 7 days before the biochemical assays or test for memory functions were carried out. JB was found to produce a significant increase in the level of alternation behavior compared with the control, suggesting anti-amnesic activity. Also, JB reversed the memory impairment induced by scopolamine, which further indicates anti-amnesic property. Furthermore, JB demonstrated a significant inhibition of MDA formation in the frontal cortex and hippocampus of rats, indicating antioxidant property. In addition, it increased the defense armory of the brain tissues, as it significantly increased the concentrations of GSH in the frontal cortex and hippocampus of rats. However, JB did not demonstrate any inhibitory effect against AChE activity in the frontal cortex and hippocampus of rats in comparison with the control group. This

Jolkinolide B inhibits RANKL-induced osteoclastogenesis by suppressing the activation NF-κB and MAPK signaling pathways.

PubMed

Ma, Xiaojun; Liu, Yupeng; Zhang, Yao; Yu, Xiaobing; Wang, Weiming; Zhao, Dewei

2014-03-07

Osteoclasts together with osteoblasts play pivotal roles in bone remodeling. The unique function and ability of osteoclasts to resorb bone makes them critical in both normal bone homeostasis and pathologic bone diseases such as osteoporosis and rheumatoid arthritis. Thus, new compounds that may inhibit osteoclastogenesis and osteoclast function may be of great value in the treatment of osteoclast-related diseases. In the present study, we examined the effect of jolkinolide B (JB), isolated from the root of Euphorbia fischeriana Steud on receptor activator of NF-κB ligand (RANKL)-induced osteoclast formation. We found that JB inhibited RANKL-induced osteoclast differentiation from bone marrow macrophages (BMMs) without cytotoxicity. Furthermore, the expression of osteoclastic marker genes, such as tartrate-resistant acid phosphatase (TRAP), cathepsin K (CtsK), and calcitonin receptor (CTR), was significantly inhibited. JB inhibited RANKL-induced activation of NF-κB by suppressing RANKL-mediated IκBα degradation. Moreover, JB inhibited RANKL-induced phosphorylation of mitogen-activated protein kinases (p38, JNK, and ERK). This study thus identifies JB as an inhibitor of osteoclast formation and provides evidence that JB might be an alternative medicine for preventing and treating osteolysis. Copyright © 2014 Elsevier Inc. All rights reserved.

On the nameless love and infinite sexualities: John Henry Mackay, Magnus Hirschfeld and the origins of the sexual emancipation movement.

PubMed

Bauer, J Edgar

2005-01-01

Two prominent representatives of the sexual emancipation movement in Germany, John Henry Mackay (1864-1933) and Magnus Hirschfeld (1868-1935) launched significant attacks on sexual binarism and its combinatories. Although Mackay defended the nameless love against seminal Christian and subsequent secularised misconstructions of its nature, he was unable to overcome the fundamental scheme of binomic sexuality. Hirschfeld, however, resolved the theoretical issue through his doctrine of sexual intermediaries (Zwischenstufenlehre) which purports that-without exception- all human beings are intersexual variants, i.e. unique composites of different proportions of masculinity and femininity. Since these proportions vary from one sexual layer of description to another in the same individual and can alter or be altered in time, it is sensu stricto not possible implies a radical deconstruction of not only binomic sexuality but its supplementation through a third sex. It offers a meta-theoretical framework for rethinking sexual difference beyond the fictional schemes and categorial closures of Western traditions of sexual identity. His assumption of potentially infinite sexualities anticipates some of the basic tenets forwarded by the philosophical and political agendas of queer studies. to postulate discrete sexual categories. Hirschfeld's doctrine.

Controls on sediment cover in bedrock-alluvial channels of the Henry Mountains, Utah

NASA Astrophysics Data System (ADS)

Hodge, R. A.; Yager, E.; Johnson, J. P.; Tranmer, A.

2017-12-01

The location and extent of sediment cover in bedrock-alluvial channels influences sediment transport rates, channel incision and instream ecology. However, factors affecting sediment cover and how it responds to changes in relative sediment supply have rarely been quantitatively evaluated in field settings. Using field surveys and SFM analysis of channel reach topography, we quantified sediment cover and channel properties including slope, width, grain size distributions, and bedrock and alluvial roughness in North Wash and Chelada Creek in the Henry Mountains, Utah. Along reaches where upstream sediment supply does not appear to be restricted, we find that the fraction of local bedrock exposure increases as a function of local relative transport capacity . In a downstream section of Chelada Creek, decadal-scale sediment supply has been restricted by an upstream culvert that has caused a backwater effect and corresponding upstream deposition. In this section, alluvial cover is uncorrelated with local stream power. To test the impact of relative sediment supply on sediment cover, a 1D sediment transport model was used to predict the equilibrium sediment cover in Chelada Creek under varying flow and sediment supply conditions. Sediment transport in each model section was predicted using the partial cover model of Johnson (2015), which accounts for differences in bedrock and alluvial roughness on critical shear stress and flow resistance. Model runs in which sediment supply was approximately equal to mean transport capacity produced a pattern of sediment cover which best matched the field observations upstream of the culvert. However, runs where sediment supply was under-capacity produced the pattern most similar to field observations downstream of the culvert, consistent with our field-based interpretations. Model results were insensitive to initial sediment cover, and equilibrium was relatively quickly reached, suggesting that the channel is responsive to changes in

Development of the jugular bulb: a radiologic study.

PubMed

Friedmann, David R; Eubig, Jan; McGill, Megan; Babb, James S; Pramanik, Bidyut K; Lalwani, Anil K

2011-10-01

Jugular bulb (JB) abnormalities such as JB diverticulum and high-riding JBs of the temporal bone can erode into the inner ear and present with hearing loss, vestibular disturbance, and pulsatile tinnitus. Their cause and potential to progress remain to be studied. This comprehensive radiologic study investigates the postnatal development of the venous system from transverse sinus to internal jugular vein (IJV). Academic medical center. PATIENTS, INTERVENTION, MAIN OUTCOME MEASURE: Measurements of the transverse and sigmoid sinus, the JB, IJV, and carotid artery were made from computed tomographic scans of the neck with intravenous contrast in infants (n = 5), children (n = 13), adults (n = 35), and the elderly (n = 15). Jugular bulbs were not detected in patients younger than 2 years, enlarged in adulthood, and remained stable in the elderly. The venous system was larger in men than in women. From transverse sinus to IJV, the greatest variation in size was just proximal and distal to the JB with greater symmetry observed as blood returned to the heart. Right-sided venous dominance was most common occurring in 70% to 80% of cases. The JB is a dynamic structure that forms after 2 years, and its size stabilizes in adulthood. The determinants in its exact position and size are multifactorial and may be related to blood flow. Improved understanding of this structure's development may help to better understand the cause of the high-riding JB and JB diverticulum, both of which may cause clinical symptoms.

Ability of the Multisensory Jawbone UP3 to Quantify and Classify Sleep in Patients With Suspected Central Disorders of Hypersomnolence: A Comparison Against Polysomnography and Actigraphy.

PubMed

Cook, Jesse D; Prairie, Michael L; Plante, David T

2018-04-30

To evaluate the ability of a multisensory fitness tracker, the Jawbone UP3 (JB3), to quantify and classify sleep in patients with suspected central disorders of hypersomnolence. This study included 43 patients who completed polysomnography (PSG) and a Multiple Sleep Latency Test (MSLT) with concurrent wrist-worn JB3 and Actiwatch 2 (AW2) recordings for comparison. Mean differences in nocturnal sleep architecture variables were compared using Bland-Altman analysis. Sensitivity, specificity, and accuracy were derived for both devices relative to PSG. Ability of the JB3 to detect sleep onset rapid eye movement periods (SOREMPs) during MSLT naps was also quantified. JB3 demonstrated a significant overestimation of total sleep time (39.6 min, P < .0001) relative to PSG, but performed comparably to AW2. Although the ability of the JB3 to detect epochs of sleep was relatively good (sensitivity = 0.97), its ability to distinguish light, deep, and REM sleep was poor. Similarly, the JB3 did not correctly identify a single SOREMP during any MSLT nap opportunity. The JB3 did not accurately quantify or classify sleep in patients with suspected central disorders of hypersomnolence, and was particularly poor at identifying REM sleep. Thus, this device cannot be used as a surrogate for PSG or MSLT in the assessment of patients with suspected central disorders of hypersomnolence. Copyright © 2018 American Academy of Sleep Medicine. All rights reserved.

J.B. Nash Lecture Series.

ERIC Educational Resources Information Center

Gray, Howard R., Comp.; And Others

The following lectures are presented in this publication: (1) "The Dynamics of Recreation" (Betty Van der Smissen); (2) "Recreation Prospects" (Edith L. Ball); (3) "A View of the Past--A Bridge to the Future" (Allen V. Sapora); (4) "Coming to Grips with the New Leisure" (Richard G. Kraus); (5) "The Mild Blue Yonder--Changing Lifestyles and…

The Third Battle: Innovation in the U.S. Navy’s Silent Cold War Struggle with Soviet Submarines (Newport Paper No. 16, 2003)

DTIC Science & Technology

2003-01-01

Bonin , Colleen Leonardo, Bruce Rule, John Hanley, Dick Chapman, Greg Duckworth, Ted Wile, Captain Dave Schubert, Jan Breemer, John Brandes, Robert...Nadolink, Jeff Cohen, Bernie Myer, Hal Hultgreen, Dick Bonin , and Colleen Leo- nardo, 13 March 1998. For more on what came to be known as the Atlantic

In memoriam/À la mémoire de

USDA-ARS?s Scientific Manuscript database

Richard (Dick) Stace-Smith (1924 - 2017) was born in Creston, British Columbia. He received his B.Sc. degree in Agriculture from University of British Columbia in 1950 and Ph.D. from Oregon State University in 1954. Dick worked at the Agriculture Canada, later renamed Agriculture and Agri-Food Canad...

Fatty acid profiles and adipogenic gene expression of various fat depots in Japanese Black and Holstein steers.

PubMed

Shirouchi, Bungo; Albrecht, Elke; Nuernberg, Gerd; Maak, Steffen; Olavanh, Samadmanivong; Nakamura, Yoshinori; Sato, Masao; Gotoh, Takafumi; Nuernberg, Karin

2014-01-01

Objective of the study was to assess the breed effect on fatty acid (FA) composition of different adipose tissues and on mRNA expression of genes involved in adipogenesis and fat metabolism. Japanese Black (JB) and Holstein (HS) steers were kept under equivalent conditions with high energy intake resulting in large differences in intramuscular fat (IMF) accumulation in longissimus muscle (LM). The relative FA composition of muscle, intermuscular fat, visceral fat, and perirenal fat was comparable between JB and HS steers. Circulating fatty acids were also similar in both breeds. Most relevant breed effects were identified in IMF, underlining the uniqueness of this adipose tissue site. JB steers had more monounsaturated FA and less saturated FA. Perilipin 1 and adipose differentiation-related protein (ADFP) mRNA levels were higher in IMF of JB. The results suggest advanced maturity of IMF cells in JB and altered local conditions in muscle influencing IMF accumulation and composition. © 2013.

Jolkinolide A and Jolkinolide B Inhibit Proliferation of A549 Cells and Activity of Human Umbilical Vein Endothelial Cells.

PubMed

Shen, Lei; Zhang, Shan-Qiang; Liu, Lei; Sun, Yu; Wu, Yu-Xuan; Xie, Li-Ping; Liu, Ji-Cheng

2017-01-14

BACKGROUND Jolkinolide A (JA) and Jolkinolide B (JB) are diterpenoids extracted from the roots of Euphorbia fischeriana Steud and have been shown to have anti-tumor activity. However, their effects on the ability of tumor cells to invade blood vessels and metastasize remain largely unknown. Investigations into the effects of JA and JB on the angiogenesis of tumor tissues may facilitate the identification of new natural drugs with anti-tumor growth and metastasis activities. MATERIAL AND METHODS We used different concentrations of JA and JB (20 μg/ml, 40 μg/ml, 60 μg/ml, 80 μg/ml, and 100 μg/ml) to stimulate A549 cells and then studied the effects on the growth and metastasis of lung cancers. In addition, we used conditional media from A549 cells (A549-CM) stimulated by either JA or JB in different concentrations to culture human umbilical vein endothelial cells (HUVECs). RESULTS We found that both JA and JB significantly inhibited the Akt-STAT3-mTOR signaling pathway and reduced the expression of VEGF in A549 cells, but JB exhibited more significant inhibitory effects than JA. The JB-stimulated A549 cell conditional media had a greater inhibitory effect on the proliferation and migration of HUVECs than did the conditional media of JA-stimulated A549 cells. This effect gradually increased with increasing concentrations of either type of Jolkinolide. CONCLUSIONS Our results suggest that JA and JB inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs. These findings are of great significance for the development of new plant-derived chemotherapy agents for the treatment of cancer.

Jolkinolide A and Jolkinolide B Inhibit Proliferation of A549 Cells and Activity of Human Umbilical Vein Endothelial Cells

PubMed Central

Shen, Lei; Zhang, Shan-Qiang; Liu, Lei; Sun, Yu; Wu, Yu-Xuan; Xie, Li-Ping; Liu, Ji-Cheng

2017-01-01

Background Jolkinolide A (JA) and Jolkinolide B (JB) are diterpenoids extracted from the roots of Euphorbia fischeriana Steud and have been shown to have anti-tumor activity. However, their effects on the ability of tumor cells to invade blood vessels and metastasize remain largely unknown. Investigations into the effects of JA and JB on the angiogenesis of tumor tissues may facilitate the identification of new natural drugs with anti-tumor growth and metastasis activities. Material/Methods We used different concentrations of JA and JB (20 μg/ml, 40 μg/ml, 60 μg/ml, 80 μg/ml, and 100 μg/ml) to stimulate A549 cells and then studied the effects on the growth and metastasis of lung cancers. In addition, we used conditional media from A549 cells (A549-CM) stimulated by either JA or JB in different concentrations to culture human umbilical vein endothelial cells (HUVECs). Results We found that both JA and JB significantly inhibited the Akt-STAT3-mTOR signaling pathway and reduced the expression of VEGF in A549 cells, but JB exhibited more significant inhibitory effects than JA. The JB-stimulated A549 cell conditional media had a greater inhibitory effect on the proliferation and migration of HUVECs than did the conditional media of JA-stimulated A549 cells. This effect gradually increased with increasing concentrations of either type of Jolkinolide. Conclusions Our results suggest that JA and JB inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs. These findings are of great significance for the development of new plant-derived chemotherapy agents for the treatment of cancer. PMID:28087861

Wave functions of the Q .Q interaction in terms of unitary 9-j coefficients

NASA Astrophysics Data System (ADS)

Zamick, Larry; Harper, Matthew

2015-03-01

We obtain wave functions for two protons and two neutrons in the g9 /2 shell expressed as column vectors with amplitudes D (Jp,Jn) . When we use a quadrupole-quadrupole interaction (Q .Q ) we get, in many cases, a very strong overlap with wave functions given by a single set of unitary 9-j coefficients—U 9 j =<(jj ) 2 j(jjJB|(jj ) Jp(jj ) Jn) I> . Here JB=9 for even I T =0 states. For both even and odd T =1 states we take JB equal to 8 whilst for odd I ,T =0 we take JB to be 7. We compare the Q .Q results with those of a more realistic interaction.

The Henry reaction of (1R)-(1,4:3,6-dianhydro-D-mannitol-2-yl)-1,4:3,6-dianhydro-D-fructose 5,5'-dinitrate. Different reactive features of nitromethane to nitroethane.

PubMed

Liu, Feng-Wu; Wang, Zhen-Ji; Song, Xiao-Ping; Zhang, Sai-Yang; Liu, Hong-Min

2009-12-14

Henry reactions of a novel higher sugar derivative, (1R)-(1,4:3,6-dianhydro-D-mannitol-2-yl)-1,4:3,6-dianhydro-D-fructose 5,5'-dinitrate (Alternate nomenclature: (1R)-(isomannid-2-yl)-1,4:3,6-dianhydro-D-fructose 5,5'-dinitrate), with nitromethane and nitroethane were studied. The kinetic and thermodynamic reactions with nitromethane under different conditions were carried out to afford (2S)- and (2R)-beta-nitroalcohols, respectively. But when using nitroethane the reaction gave a (2S)-beta-nitroalcohol with an inverted configuration at vicinal carbon C-1. Two stereogenic centers were generated, and one was altered in the reaction.

EPI-SPIRE: A Bio-Surveillance Prototype

DTIC Science & Technology

2005-05-01

application to Lyme disease vectors. Intl J GIS 16:151-166. Glass, GE, TL Yates, JB Fine, TM Shields, JB Kendall, AG Hope, CA Parmenter CJ Peters, TG...EB Hayes & BS Schwartz. 2003. Longitudinal evaluation of an educational intervention to prevent tick bites in an area of endemic Lyme disease in...34. Fine, JB, JL Robertson, GE Glass. 2004. Borrelia burgdorferi exposure in asymptomatic populations of horses in Maryland and Virginia. Am J Vet

Nitropelagi marinus gen. nov., sp. nov., Isolated From Seawater, Je-bu island, South Korea.

PubMed

Jeong, Sun Hwan; Lee, Sang Seob

2016-09-01

A Gram-stain-negative, non-spore forming, non-motile and aerobic strain, designated JB22(T), was isolated from seawater, Je-bu Island, South Korea. Strain JB22(T) was catalase and oxidase positive. Optimal growth of JB22(T) was observed at 30 °C and pH 7.0. NaCl tolerance range was 1-9 % (w/v) with an optimum of 2.0 % concentration. The phylogenetic analysis based on 16S rRNA gene sequence of strain JB22(T) showed the highest sequence similarity to those of Pelagicola litorisediminis D1-W8(T) (95.8 %), Roseovarius litoreus GSW-M15(T) (95.2 %), Roseovarius aestuarii SMK-122(T) (95.0 %), Donghicola eburmeus SW-277(T) (95.0 %), and Roseovarius halotolerans HJ50(T) (94.9 %). It contained ubiquine-10 as the major respiratory quinone and C18:1 ω7c (69.3 %), :0 (9.9 %), C18:1 ω7c 11-methyl (9.6 %) as the major fatty acid. The polar lipid profile included phosphatidylcholine, phosphatidylglycerol, and unidentified aminolipid. The DNA G+C content of the strain JB22(T) was 47 mol  %. Based on physiological and chemotaxonomic characteristics, strain JB22(T) should be regarded as a new genus of the family Rhodobacteraceae, for which the Nitropelagi marinus gen. nov., sp. nov. is proposed. The type strain is JB22(T) (= KEMB 3001-101(T) = JCM 30822(T)).

Using Formative Assessment to Facilitate Learner Self-Regulation: A Case Study of Assessment Practices and Student Perceptions in Hong Kong

ERIC Educational Resources Information Center

Jing Jing, Ma

2017-01-01

One of the key aims of formative assessment in higher education is to enable students to become self-regulated learners (Nicol & Macfarlane-Dick, 2006). Based on Nicol and Macfarlane-Dick's (2006) framework, this exploratory study investigates which formative assessment practices proposed by them were used by one college EFL writing teacher to…

Rib fracture - aftercare

MedlinePlus

... Alternative Names Broken rib - aftercare References Browner BD, Jupiter JB, Krettek C, Anderson PA. Scapula and rib fractures. In: Browner BD, Jupiter JB, Krettek C, Anderson PA, eds. Skeletal Trauma: ...

New hematological key for bovine leukemia virus-infected Japanese Black cattle.

PubMed

Mekata, Hirohisa; Yamamoto, Mari; Kirino, Yumi; Sekiguchi, Satoshi; Konnai, Satoru; Horii, Yoichiro; Norimine, Junzo

2018-02-20

The European Community's (EC) Key, which is also called Bendixen's Key, is a well-established bovine leukemia virus (BLV) diagnostic method that classifies cattle according to the absolute lymphocyte count and age. The EC Key was originally designed for dairy cattle and is not necessarily suitable for Japanese Black (JB) beef cattle. This study revealed the lymphocyte counts in the BLV-free and -infected JB cattle were significantly lower than those in the Holstein cattle. Therefore, applying the EC Key to JB cattle could result in a large number of undetected BLV-infected cattle. Our proposed hematological key, which was designed for JB cattle, improves the detection of BLV-infected cattle by approximately 20%. We believe that this study could help promote BLV control.

Electrophysiological markers predicting impeding AV-block during ablation of atrioventricular nodal reentry tachycardia.

PubMed

Fragakis, Nikolaos; Krexi, Lydia; Kyriakou, Panagiota; Sotiriadou, Melani; Lazaridis, Charalambos; Karamanolis, Athanasios; Dalampyras, Panagiotis; Tsakiroglou, Stelios; Skeberis, Vassilios; Tsalikakis, Dimitrios; Vassilikos, Vassilios

2018-01-01

Radiofrequency (RF) ablation of the slow pathway (SP) in atrioventricular nodal reentry tachycardia (AVNRT) is occasionally complicated with atrioventricular block (AVB) often predicted by junctional beats (JB) with loss of ventriculo-atrial (VA) conduction. We analyzed retrospectively 153 patients undergoing ablation of SP for typical AVNRT. Patients were divided into two age groups: 127 ≤ 70 years and 26 > 70 years. We analyzed the interval between the atrial electrogram in the His-bundle position and the distal ablation catheter [A(H)-A(RFd)] and between the distal ablation catheter and the proximal coronary sinus catheter [A(RFd)-A(CS)] before RF applications with and without JB. We evaluated if these intervals can be used as predictors of JB incidence and also of JB with loss of VA conduction. We also assessed if age influences the risk of loss of VA conduction. The A(H)-A(RFd) and A(RFd)-A(CS) intervals were significantly shorter in RF applications causing JB than those without JB (33 ± 11 ms vs 39 ± 9 ms, P < 0.001, 14 ± 9 ms vs 20 ± 7 ms, P < 0.001, respectively). The A(H)-A(RFd) and A(RFd)-A(CS) intervals were also significantly shorter in RFs causing JB with VA block than those with VA conduction (29 ± 11 ms vs 35 ± 11 ms, P < 0.001, 8 ± 8 ms vs 17 ± 8 ms, P < 0.001, respectively). Patients > 70 years had shorter intervals (36 ± 11 ms vs 29 ± 8 ms, P  =  0.012, 17 ± 8 ms vs 13 ± 7 ms, P  =  0.027, respectively), while VA block was more common in this age group. The A(H)-A(RFd) and A(RFd)-A(CS) intervals can be used as markers for predicting JB occurrence as well as impending AVB. JB with loss of VA conduction occur more often in older patients possibly due to a higher position of SP. © 2017 Wiley Periodicals, Inc.

Effect of Vertical Shoot-Positioned, Scott-Henry, Geneva Double-Curtain, Arch-Cane, and Parral Training Systems on the Volatile Composition of Albariño Wines.

PubMed

Vilanova, Mar; Genisheva, Zlatina; Tubio, Miguel; Álvarez, Katia; Lissarrague, Jose Ramón; Oliveira, José Maria

2017-09-08

Viticultural practices influence both grape and wine quality. The influence of training systems on volatile composition was investigated for Albariño wine from Rías Baixas AOC in Northwest Spain. The odoriferous contribution of the compounds to the wine aroma was also studied. Volatile compounds belonging to ten groups (alcohols, C₆-compounds, ethyl esters, acetates, terpenols, C 13 -norisoprenoids, volatile phenols, volatile fatty acids, lactones and carbonyl compounds) were determined in Albariño wines from different training systems, Vertical Shoot-Positioned (VSP), Scott-Henry (SH), Geneva Double-Curtain (GDC), Arch-Cane (AC), and Parral (P) during 2010 and 2011 vintages. Wines from GDC showed the highest total volatile composition with the highest concentrations of alcohols, ethyl esters, fatty acids, and lactones families. However, the highest levels of terpenes and C 13 -norisoprenoids were quantified in the SH system. A fruitier aroma was observed in Albariño wines from GDC when odor activity values were calculated.

Light-quarks Yukawa couplings and new physics in exclusive high-pT Higgs boson +jet and Higgs boson + b -jet events

NASA Astrophysics Data System (ADS)

Cohen, Jonathan; Bar-Shalom, Shaouly; Eilam, Gad; Soni, Amarjit

2018-03-01

We suggest that the exclusive Higgs +light (or b)-jet production at the LHC, p p →h +j (jb), is a rather sensitive probe of the light-quarks Yukawa couplings and of other forms of new physics (NP) in the Higgs-gluon h g g and quark-gluon q q g interactions. We study the Higgs pT-distribution in p p →h +j (jb)→γ γ +j (jb), i.e., in h +j (jb) production followed by the Higgs decay h →γ γ , employing the (pT-dependent) signal strength formalism to probe various types of NP which are relevant to these processes and which we parametrize either as scaled Standard Model (SM) couplings (the kappa-framework) and/or through new higher dimensional effective operators (the SMEFT framework). We find that the exclusive h +j (jb) production at the 13 TeV LHC is sensitive to various NP scenarios, with typical scales ranging from a few TeV to O (10 ) TeV , depending on the flavor, chirality and Lorentz structure of the underlying physics.

Reply to Comment by W. R. Peltier, D. F. Argus, and R. Drummond on "An Assessment of the ICE6G_C (VM5a) Glacial Isostatic Adjustment Model"

NASA Astrophysics Data System (ADS)

Purcell, A.; Tregoning, P.; Dehecq, A.

2018-02-01

The empirical approximation of Purcell et al. (2011, https://doi.org/10.1029/2011GL048624) has been validated by Peltier et al. (2018, https://doi.org/10.1002/2016JB013844). In their Comment they introduced new results derived from the same ice/rheology models of ICE6G_C (VM5a) but using a different model for Antarctic bathymetry. This has greatly reduced the differences in predicted Antarctic uplift rates relative to those of Purcell et al. (2016, https://doi.org/10.1002/2015JB012742). In fact, with a ˜50% reduction in uplift rate in the Weddell Sea, the results of Peltier et al. (2018, https://doi.org/10.1002/2016JB013844) now agree more closely with the predictions of Purcell et al. (2016, https://doi.org/10.1002/2015JB012742) than with the original ICE6G_C values. Peltier et al. (2018, https://doi.org/10.1002/2016JB013844) state that the high power in their high-frequency spherical harmonic coefficients remains in their new calculations. They also claim that Purcell et al. (2016, https://doi.org/10.1002/2015JB012742) used an inaccurate loading history in deriving their velocity field. In fact, the ice load history was unchanged; to remove any ambiguity, the ice and water load histories used in the CALSEA calculations are provided in the supporting information.

Jolkinolide B induces apoptosis and inhibits tumor growth in mouse melanoma B16F10 cells by altering glycolysis.

PubMed

Gao, Caixia; Yan, Xinyan; Wang, Bo; Yu, Lina; Han, Jichun; Li, Defang; Zheng, Qiusheng

2016-10-31

Most cancer cells preferentially rely on glycolysis to produce the energy (adenosine triphosphate, ATP) for growth and proliferation. Emerging evidence demonstrates that the apoptosis in cancer cells could be closely associated with the inhibition of glycolysis. In this study, we have found that jolkinolide B (JB), a bioactive diterpenoid extracted from the root of Euphorbia fischeriana Steud, induced tumor cells apoptosis and decreased the production of ATP and lactic acid in mouse melanoma B16F10 cells. Furthermore, we found that JB downregulated the mRNA expression of glucose transporter genes (Glut1, Glut3 and Glut4) and glycolysis-related kinase genes (Hk2 and Ldha) in B16F10 cells. Moreover, treatment with JB upregulated the mRNA expression of pro-apoptosis genes (Bax), downregulated the mRNA expression of anti-apoptosis genes (Bcl-2, Caspase-3 and Caspase-9), decreased the potential of mitochondrial membrane and increased reactive oxygen species (ROS) levels in B16F10 cells. Finally, intragastric administration of JB suppressed tumor growth and induced tumor apoptosis in mouse xenograft model of murine melanoma B16F10 cells. Taken together, these results suggest that JB could induce apoptosis through the mitochondrial pathway and inhibit tumor growth. The inhibition of glycolysis could play a crucial role in the induction of apoptosis in JB-treated B16F10 cells.

Association of the expression levels in the skeletal muscle and a SNP in the CDC10 gene with growth-related traits in Japanese Black beef cattle.

PubMed

Tong, B; Li, G P; Sasaki, S; Muramatsu, Y; Ohta, T; Kose, H; Yamada, T

2015-04-01

Growth performance, as well as marbling, is the main breeding objective in Japanese Black (JB) cattle, the major beef breed in Japan. The septin 7 (CDC10) gene, involved in cellular proliferation, is located within a genomic region of a quantitative trait locus for growth-related traits. In this study, we first showed that the expression levels of the CDC10 gene in the skeletal muscle were higher in JB steers with extremely high growth performance than in JB steers with extremely low growth, using real-time PCR. Further, a single nucleotide polymorphism (SNP), NC_007302.5:g.63264949G>C, was detected in the promoter region of the CDC10 gene and genotyped in three Japanese cattle breeds (known as 'Wagyu' in Japan) and the Brown Swiss dairy cattle breed. All four cattle populations showed a moderate genetic diversity at the SNP of the CDC10 gene. An association analysis indicated that the SNP was associated with growth-related traits in JB cattle. These findings suggest possible effects of the expression levels in the skeletal muscle and the SNP of the CDC10 gene on growth-related traits in JB cattle. The CDC10 SNP may be useful for effective marker-assisted selection to increase beef productivity in JB beef cattle. © 2015 Stichting International Foundation for Animal Genetics.

Jolkinolide B induces apoptosis and inhibits tumor growth in mouse melanoma B16F10 cells by altering glycolysis

PubMed Central

Gao, Caixia; Yan, Xinyan; Wang, Bo; Yu, Lina; Han, Jichun; Li, Defang; Zheng, Qiusheng

2016-01-01

Most cancer cells preferentially rely on glycolysis to produce the energy (adenosine triphosphate, ATP) for growth and proliferation. Emerging evidence demonstrates that the apoptosis in cancer cells could be closely associated with the inhibition of glycolysis. In this study, we have found that jolkinolide B (JB), a bioactive diterpenoid extracted from the root of Euphorbia fischeriana Steud, induced tumor cells apoptosis and decreased the production of ATP and lactic acid in mouse melanoma B16F10 cells. Furthermore, we found that JB downregulated the mRNA expression of glucose transporter genes (Glut1, Glut3 and Glut4) and glycolysis-related kinase genes (Hk2 and Ldha) in B16F10 cells. Moreover, treatment with JB upregulated the mRNA expression of pro-apoptosis genes (Bax), downregulated the mRNA expression of anti-apoptosis genes (Bcl-2, Caspase-3 and Caspase-9), decreased the potential of mitochondrial membrane and increased reactive oxygen species (ROS) levels in B16F10 cells. Finally, intragastric administration of JB suppressed tumor growth and induced tumor apoptosis in mouse xenograft model of murine melanoma B16F10 cells. Taken together, these results suggest that JB could induce apoptosis through the mitochondrial pathway and inhibit tumor growth. The inhibition of glycolysis could play a crucial role in the induction of apoptosis in JB-treated B16F10 cells. PMID:27796318

Human Factors in Industrial and Consumer Products and Services

DTIC Science & Technology

2006-03-24

modeling; simulation and intelligent agents; Transportation ; Space and aviation; Telecommunication and web applications; Consumer products; and Customer...the user feedback throughout the product development. Self-explaining and forgiving roads to improve safety Karel Brookhuis, Dick de Waard...in a simulated ambulance dispatcher’s task Ben Mulder, Anje Kruizinga & Dick de Waard University of Groningen, Experimental and Work Psychology

Munitions Executive Summit 2010 Held in San Diego, California on February 8-10, 2010

DTIC Science & Technology

2010-02-10

INDUSTRIAL CAPABILITIES · Mr. Dick Hammett , President, Winchester Ammunition AMMUNITION ENTERPRISE CROSS SERVICE PANEL PANEL CHAIR: BG Jonathan...complacency 7 Aligning Commercial Industrial Capabilities with Munitions Requirements & Resources Dick Hammett , President, Winchester Ammunition...Immature – Quantum Dot FPAs maturing – Devices have been demonstrated under less than optimal conditions – Measured results equate to less than 0.1

DESIGN OF MEDICAL RADIOMETER FRONT-END FOR IMPROVED PERFORMANCE

PubMed Central

Klemetsen, Ø.; Birkelund, Y.; Jacobsen, S. K.; Maccarini, P. F.; Stauffer, P. R.

2011-01-01

We have investigated the possibility of building a singleband Dicke radiometer that is inexpensive, small-sized, stable, highly sensitive, and which consists of readily available microwave components. The selected frequency band is at 3.25–3.75 GHz which provides a reasonable compromise between spatial resolution (antenna size) and sensing depth for radiometry applications in lossy tissue. Foreseen applications of the instrument are non-invasive temperature monitoring for breast cancer detection and temperature monitoring during heating. We have found off-the-shelf microwave components that are sufficiently small (< 5 mm × 5 mm) and which offer satisfactory overall sensitivity. Two different Dicke radiometers have been realized: one is a conventional design with the Dicke switch at the front-end to select either the antenna or noise reference channels for amplification. The second design places a matched pair of low noise amplifiers in front of the Dicke switch to reduce system noise figure. Numerical simulations were performed to test the design concepts before building prototype PCB front-end layouts of the radiometer. Both designs provide an overall power gain of approximately 50 dB over a 500 MHz bandwidth centered at 3.5 GHz. No stability problems were observed despite using triple-cascaded amplifier configurations to boost the thermal signals. The prototypes were tested for sensitivity after calibration in two different water baths. Experiments showed superior sensitivity (36% higher) when implementing the low noise amplifier before the Dicke switch (close to the antenna) compared to the other design with the Dicke switch in front. Radiometer performance was also tested in a multilayered phantom during alternating heating and radiometric reading. Empirical tests showed that for the configuration with Dicke switch first, the switch had to be locked in the reference position during application of microwave heating to avoid damage to the active components

Materials Science and Engineering-1989 Publications (Naval Research Laboratory)

DTIC Science & Technology

1991-03-29

34 D.G. Cory, J.B. Miller, A.N. Garroway "Acousto-Optic and Linear Electro-Optic Journal of Magnetic Resonance, 85, 219 Properties of Organic Polymeric...34Demonstration of Indirect Detection of ൕC Refocused Gradient Imaging of Solids" 14N Overtone NMR Transitions" J.B. Miller, A.N. Garroway A.N. Garroway , J.B...Conductive Polymer Solids" Chemical Vapor Sensors" J.B. Miller, A.N. Garroway J.F. Giuiani, T.M. Keller Journal of Magnetic Resonance, 85, 255 Journal of