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Sample records for digboiensis teri asn6

  1. Candida digboiensis sp. nov., a novel anamorphic yeast species from an acidic tar sludge-contaminated oilfield.

    PubMed

    Prasad, G S; Mayilraj, S; Sood, Nitu; Singh, Vijeyta; Biswas, Kakoli; Lal, Banwari

    2005-03-01

    Two strains (TERI-6(T) and TERI-7) of a novel yeast species were isolated from acidic tar sludge-contaminated soil samples collected from Digboi Refinery, Assam, India. These two yeast strains were morphologically, physiologically and phylogenetically identical to each other. No sexual reproduction was observed on corn meal, malt, Gorodkowa, YM or V8 agars. Physiologically, the novel isolates were most closely related to Candida blankii, but differed in eight physiological tests. The prominent differences were the ability of the isolates to assimilate melibiose and inulin and their inability to assimilate d-glucuronate, succinate and citrate. Phylogenetic analysis using the D1/D2 variable domain showed that the closest relative of these strains is C. blankii (2.8 % divergence). Other related species are Zygoascus hellenicus and Candida bituminiphila. The isolates differed from C. blankii by 11 base substitutions in the 18S rRNA gene sequence and by 58 base substitutions in the internal transcribed spacer sequences. The physiological, biochemical and molecular data support the contention that strains TERI-6(T) and TERI-7 represent a novel species, for which the name Candida digboiensis sp. nov. is proposed. The type strain is TERI-6(T) (=MTCC 4371(T)=CBS 9800(T)=JCM 12300(T)). PMID:15774693

  2. Electronic Library: A TERI Experiment.

    ERIC Educational Resources Information Center

    Kar, Debal C.; Deb, Subrata; Kumar, Satish

    2003-01-01

    Discusses the development of Electronic Library at TERI (The Energy and Resources Institute, New Delhi). Highlights include: hardware and software used; the digital library/Virtual Electronic Library; directory of Internet journals; virtual reference resources; electronic collection/Physical Electronic Library; downloaded online full-length…

  3. Isolation and characterization of a potential paraffin-wax degrading thermophilic bacterial strain Geobacillus kaustophilus TERI NSM for application in oil wells with paraffin deposition problems.

    PubMed

    Sood, Nitu; Lal, Banwari

    2008-02-01

    Paraffin deposition problems, that have plagued the oil industry, are currently remediated by mechanical and chemical means. However, since these methods are problematic, a microbiological approach has been considered. The bacteria, required for the mitigation of paraffin deposition problems, should be able to survive the high temperatures of oil wells and degrade the paraffins under low oxygen and nutrient conditions while sparing the low carbon chain paraffins. In this study, a thermophilic paraffinic wax degrading bacterial strain was isolated from a soil sample contaminated with paraffinic crude oil. The selected strain, Geobacillus TERI NSM, could degrade 600mg of paraffinic wax as the sole carbon source in 1000ml minimal salts medium in 7d at 55 degrees C. This strain was identified as Geobacillus kaustophilus by fatty acid methyl esters analysis and 16S rRNA full gene sequencing. G. kaustophilus TERI NSM showed 97% degradation of eicosane, 85% degradation of pentacosane and 77% degradation of triacontane in 10d when used as the carbon source. The strain TERI NSM could also degrade the paraffins of crude oil collected from oil wells that had a history of paraffin deposition problems. PMID:17942139

  4. Bioflocculant production and biosorption of zinc and lead by a novel bacterial species, Achromobacter sp. TERI-IASST N, isolated from oil refinery waste.

    PubMed

    Subudhi, Sanjukta; Batta, Neha; Pathak, Mihirjyoti; Bisht, Varsha; Devi, Arundhuti; Lal, Banwari; Al khulifah, Bader

    2014-10-01

    A bioflocculant-producing bacterial isolate designated as 'TERI-IASST N' was isolated from activated sludge samples collected from an oil refinery. This isolate demonstrated maximum bioflocculation activity (74%) from glucose among 15 different bioflocculant-producing bacterial strains isolated from the sludge samples and identified as Achromobacter sp. based on 16S rRNA gene sequence. Optimization of pH and supplementation of urea as nitrogen source in the production medium enhanced the flocculation activity of strain TERI-IASST N to 84% (at pH 6). This strain revealed maximum flocculation activity (90%) from sucrose compared to the flocculation activity observed from other carbon sources as investigated (glucose, lactose, fructose, maltose and starch). Ca(2+) served as the suitable divalent cation for maximum bioflocculation activity of TERI-IASST strain N. Maximum flocculation activity was observed at optimum C/N ratio of 1. Flocculation activity of this strain decreased to 75% in the presence of heavy metals; Zn, Pb, Ni, Cu and Cd. In addition strain N revealed considerable biosorption of Zn (430mgL(-1)) and Pb (30mgL(-1)). Bioflocculant yield of strain N was 10.5gL(-1). Fourier transform infrared spectrum indicated the presence of carboxyl, hydroxyl, and amino groups, typical of glycoprotein. Spectroscopic analysis of bioflocculant by nuclear magnetic resonance revealed that it is a glycoprotein, consisting of 57% total sugar and 13% protein. PMID:25065798

  5. Environmental Management Systems for Educational Institutions: A Case Study of Teri University, New Delhi

    ERIC Educational Resources Information Center

    Jain, Suresh; Pant, Pallavi

    2010-01-01

    Purpose: The purpose of this paper is to put forth a model for implementation of an environmental management system (EMS) in institutes of higher education in India. Design/methodology/approach: The authors carried out initial environmental review (IER) and strengths, weaknesses, opportunities and threats (SWOT) analysis to identify the major…

  6. Debunking the Myth-tery: How the New AASL Standards Unplugged Mythology

    ERIC Educational Resources Information Center

    Hubbard, Erin E.

    2009-01-01

    Though few students realize it, many things in today's culture exist because of mythology. This article argues that library media specialists and teachers can teach mythology but it must be applied to the 21st century and shown its relevance in today's world. The article demonstrates that mythology studies are alive and well when the new AASL…

  7. Use of an acidophilic yeast strain to enable the growth of leaching bacteria on solid media.

    PubMed

    Ngom, Baba; Liang, Yili; Liu, Yi; Yin, Huaqun; Liu, Xueduan

    2015-03-01

    In this study, a Candida digboiensis strain was isolated from a heap leaching plant in Zambia and used in double-layer agar plate to efficiently isolate and purify leaching bacteria. Unlike Acidiphilium sp., the yeast strain was tetrathionate tolerant and could metabolize a great range of organic compounds including organic acids. These properties allowed the yeast strain to enable and fasten the growth of iron and sulfur oxidizers on double-layer agar plate. The isolates were identified as Acidithiobacillus ferrooxidans FOX1, Leptospirillun ferriphilum BN, and Acidithiobacillus thiooxidans ZMB. These three leaching bacteria were inhibited by organic acids such as acetic and propionic acids; however, their activities were enhanced by Candida digboiensis NB under dissolved organic matter stress. PMID:25347960

  8. Bold Books for Innovative Teaching

    ERIC Educational Resources Information Center

    Gallo, Don

    2004-01-01

    The ways in which Teri Lesesne, an author, selects the best book from the hundreds of books published each year are discussed. The importance of understanding the needs of the readers and the curriculum is explained.

  9. A Young University in India Focuses on Real-World Industry and Sustainability

    ERIC Educational Resources Information Center

    Neelakantan, Shailaja

    2009-01-01

    A small, relatively new Indian university is making a name for itself--nationally and internationally--in the rapidly growing field of sustainable development. TERI University, the creation of one of India's leading environmentalists, has won praise from industry executives and academics alike. They say the institution is tackling some of the…

  10. DRINKING WATER ISSUES

    EPA Science Inventory

    According to recent reports by the California Department of Health Services, the State of Maine, and the United State Geological Survey (USGS); the fuel oxygenate methyl teri-butyl ether (MTBE) is present in 5 to 20 percent of the drinking water sources in California and the nort...

  11. CHEMICAL ANALYSIS OF WORLD TRADE CENTER FINE PARTICULATE MATTER FOR USE IN TOXICOLOGICAL ASSESSMENT

    EPA Science Inventory

    Chemical Analysis of World Trade Center Fine Particulate Matter for Use in Toxicological Assessment
    John K. McGee1, Lung Chi Chen2, Mitchell D. Cohen2, Glen R. Chee2, Colette M. Prophete2, Najwa Haykal-Coates1, Shirley J. Wasson3, Teri L. Conner4, Daniel L. Costa1, and Steph...

  12. From Numbers to Letters: Feedback Regularization in Visual Word Recognition

    ERIC Educational Resources Information Center

    Molinaro, Nicola; Dunabeitia, Jon Andoni; Marin-Gutierrez, Alejandro; Carreiras, Manuel

    2010-01-01

    Word reading in alphabetic languages involves letter identification, independently of the format in which these letters are written. This process of letter "regularization" is sensitive to word context, leading to the recognition of a word even when numbers that resemble letters are inserted among other real letters (e.g., M4TERI4L). The present…

  13. Comparison of the kinetics of iron release from a marine (Trichodesmium erythraeum) Dps protein and mammalian ferritin in the presence and absence of ligands.

    PubMed

    Castruita, Madeli; Elmegreen, Lauren A; Shaked, Yeala; Stiefel, Edward I; Morel, François M M

    2007-11-01

    The ferritin superfamily of iron storage proteins includes ferritin proper and Dps (DNA binding protein from starved cells) along with bacterioferritin. We examined the release of Fe from the Dps of Trichodesmium erythraeum (Dps(tery)) and compared it to the release of Fe from horse spleen ferritin (HoSF) under various conditions. Both desferrioxamine B (DFB), a Fe(III) chelator, and ascorbic acid were able to mobilize Fe from Dps(tery) at rates comparable to those observed for HoSF. The initial Fe release rate from both proteins increased linearly with the concentration of DFB, suggesting that the chelator binds to Fe in the protein. A small but significant rate obtained by extrapolation to zero concentration of DFB implies that Dps(tery) and HoSF might release Fe(III) spontaneously. A similar result was observed for HoSF in the presence of sulfoxine. In a different experiment, Fe(III) was transferred from holoferritin to apotransferrin across a dialysis membrane in the absence of chelator or reducing agent. The apparent spontaneous release of Fe from HoSF and Dps(tery) brings forth the hypothesis that the Fe core in Fe storage proteins might be continuously dissolving and re-precipitating in vivo, thus maintaining it in a highly reactive and bioavailable form. PMID:17804072

  14. Trapping systems for Zaprionus indianus (Diptera: Drosophilidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    62nd Annual Meeting of the Entomological Society of America 16-19 November 2014; Portland, OR Title: Trapping systems for Zaprionus indianus (Diptera: Drosophilidae) Nancy D. Epsky, Micah A. Gill, C. Teri Allen, Dong H. Cha, and Peter J. Landolt Nancy D. Epsky USDA-ARS, Subtropical Horticulture...

  15. Internet-based information resource and discussion platform on GHG reduction strategies in Asia

    SciTech Connect

    2000-12-28

    The website (www.ccasia.teri.res.in) provides a consolidated Internet based information source and platform for discussions on climate change issues in Asia. The effort has been successful in reaching the target audience and in stimulating awareness about the crucial debate on GHG (greenhouse gas) reduction strategies in Asia.

  16. Access to Justice: Middle School Strategies.

    ERIC Educational Resources Information Center

    Mertz, Gayle; And Others

    1989-01-01

    Gayle Mertz offers simulations covering balloting and the juvenile court system along with a legislation drafting activity. Mercedes J. Newsome provides guidance on the use of community resource persons. Teri Wilson's activity simulates a juvenile proceeding while Richard Marcroft and Elenor Taylor describe a simulation of small claims court. (KO)

  17. Not Just Needlework

    ERIC Educational Resources Information Center

    Bloom, Amy Albert

    2011-01-01

    When the author's high school students explored the work of artist Teri Greeves, they accomplished several good things. They learned about a living contemporary artist and saw the potential of art as a pursuit that is pleasurable and potentially profitable. During studio work, students tried new needlework techniques to add to their toolbox of art…

  18. Algoritmi per il calcolo dell'epatta della Luna

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2016-05-01

    On the sides of the chair of St. Hyppolitus in the Vatican Libray there is a series of 112 epacts, used for calculating the date of Christian Easter valid for 112 years from 222 AD. The algorithm of octaëteris or 8 civil (julian) years=99 lunar months and a correction of three days each 16 years or one day each 5, 5, 6 years are discussed. Four complete solar cycles (28 years), after which the sequence of the day of the week are repeating, are included in 112 years as well as 7 groups of 16 years; 112 is the minimum common multiple between the double octaëteris (16 years) and the solar cycle (28).

  19. Enhanced production of ligninolytic enzymes and decolorization of molasses distillery wastewater by fungi under solid state fermentation.

    PubMed

    Pant, Deepak; Adholeya, Alok

    2007-10-01

    Selected isolates of fungi were grown on wheat straw and corncob in the presence of different moistening agents such as water, molasses, potato dextrose broth and distillery effluent. All the fungal isolates responded differently with respect to growth and ligninolytic enzyme production. Fungal growth on different substrates was checked by calculating ergosterol content, which varied widely within a single species when grown on different substrates. The maximum laccase production was obtained for Aspergillus flavus TERI DB9 grown on wheat straw with molasses. For manganese peroxidase, highest production was in Aspergillus niger TERI DB20 grown on corncob with effluent. Among the two isolates positive for lignin peroxidase, the highest production was in Fusarium verticillioides ITCC 6140. This immobilized fungal biomass was then used for decolorization of effluent from a cane molasses based distillery. Maximum decolorization (86.33%) was achieved in Pleurotus ostreatus (Florida) Eger EM 1303 immobilized on corncob with molasses in a period of 28 days. PMID:17177104

  20. Phosphite utilization by the globally important marine diazotroph Trichodesmium.

    PubMed

    Polyviou, Despo; Hitchcock, Andrew; Baylay, Alison J; Moore, C Mark; Bibby, Thomas S

    2015-12-01

    Species belonging to the filamentous cyanobacterial genus Trichodesmium are responsible for a significant fraction of oceanic nitrogen fixation. The availability of phosphorus (P) likely constrains the growth of Trichodesmium in certain regions of the ocean. Moreover, Trichodesmium species have recently been shown to play a role in an emerging oceanic phosphorus redox cycle, further highlighting the key role these microbes play in many biogeochemical processes in the contemporary ocean. Here, we show that Trichodesmium erythraeum IMS101 can grow on the reduced inorganic compound phosphite as its sole source of P. The components responsible for phosphite utilization are identified through heterologous expression of the T. erythraeum IMS101 Tery_0365-0368 genes, encoding a putative adenosine triphosphate (ATP)-binding cassette transporter and nicotinamide adenine dinucleotide (NAD)-dependent dehydrogenase, in the model cyanobacteria Synechocystis sp. PCC6803. We demonstrate that only combined expression of both the transporter and the dehydrogenase enables Synechocystis to utilize phosphite, confirming the function of Tery_0365-0367 as a phosphite uptake system (PtxABC) and Tery_0368 as a phosphite dehydrogenase (PtxD). Our findings suggest that reported uptake of phosphite by Trichodesmium consortia in the field likely reflects an active biological process by Trichodesmium. These results highlight the diversity of phosphorus sources available to Trichodesmium in a resource-limited ocean. PMID:26081517

  1. Emplacement Scenarios for Vallis Schroteri, Aristarchus Plateau, the Moon

    NASA Technical Reports Server (NTRS)

    Garry, W. Brent; Bleacher, Jacob E.

    2011-01-01

    The volcanic processes that formed Vallis Schr teri are not well understood. Vallis Schr teri, located on the Aristarchus Plateau, is the largest rille on the Moon, and it displays three key morphologic components: the Cobra Head, the 155-km-long primary rille, and the 240-km-long inner rille. Observations of terrestrial eruptions are applied here to help explain the morphologic relationships observed for Vallis Schr teri. The Cobra Head, a 10-km-wide source vent surrounded by a 35-kmdiameter and 900-m-high low shield, might have been constructed from fl ows, spatter, and pyroclastic deposits erupted during lava fountain events, similar to the early stages of the vent at Pu u O o in Hawaii and the fi nal morphology of Bandera crater, a cinder cone in New Mexico. The vent fed an initial sheet fl ow controlled by preeruption topography. A channel formed within this sheet fl ow was the foundation for the primary rille, which deepened through construction and thermomechanical erosion by lava. The inner rille is confi ned to the fl at fl oor of the primary rille and is characterized by tight gooseneck meanders. This rille crosscuts the distal scarp of the primary rille and extends toward Oceanus Procellarum. This enigmatic relationship can be explained through backup, overfl ow, and diversion of the lava into a new rille that eroded into the margin of the primary rille. Similar backup, overfl ow, and redirection of the lava fl ow were observed during the 1984 Mauna Loa eruption in Hawaii. Analysis of the fi nal morphology of lunar rilles provides key information about lunar volcanic processes and insight into the local stratigraphy.

  2. Crystallization and preliminary X-ray diffraction analysis of the Bacillus subtilis replication termination protein in complex with the 37-base-pair TerI-binding site

    SciTech Connect

    Vivian, J. P.; Porter, C.; Wilce, J. A.; Wilce, M. C. J.

    2006-11-01

    A preparation of replication terminator protein (RTP) of B. subtilis and a 37-base-pair TerI sequence (comprising two binding sites for RTP) has been purified and crystallized. The replication terminator protein (RTP) of Bacillus subtilis binds to specific DNA sequences that halt the progression of the replisome in a polar manner. These terminator complexes flank a defined region of the chromosome into which they allow replication forks to enter but not exit. Forcing the fusion of replication forks in a specific zone is thought to allow the coordination of post-replicative processes. The functional terminator complex comprises two homodimers each of 29 kDa bound to overlapping binding sites. A preparation of RTP and a 37-base-pair TerI sequence (comprising two binding sites for RTP) has been purified and crystallized. A data set to 3.9 Å resolution with 97.0% completeness and an R{sub sym} of 12% was collected from a single flash-cooled crystal using synchrotron radiation. The diffraction data are consistent with space group P622, with unit-cell parameters a = b = 118.8, c = 142.6 Å.

  3. The relief formed by the descent phenomenon in the north-east part of Kosova.

    PubMed

    Bulliqi, Shpejtim; Isufi, Florim; Ramadani, Ibrahim; Gashi, Gani

    2012-04-01

    In the diverse relief of north-east part of Kosova a relatively wide range occupies the relief modelled by the descent phenomenon, which is conditioned by morph-structural and climatic factors quite suitable for their development. The morphogenesis activity of descent phenomenon is conditioned by the types of rocks, tectonic process of this region and climatic conditions. These factors condition horizontal and vertical relief fragmentation, slope, especially in Gollaku mountains and in SE part of Kopaonik mountain. Along the tectonic descents, the steepness is detaching and the detaching lines consisting of magmatic rocks show overthrows, demolitions and stony torrents, but the Teri gene composition formations are modelled by sliding and muddy torrents, depending upon the presence of clayey and alevrolite belts on these Teri gene ones. The impact of factors and conditions on the relief of this part, the phenomena like demolitions, overthrows, sliding, muddy torrents, stony torrents, etc, operate here, which play an important morphological role in the modelling of relief. PMID:23424844

  4. Purification and characterization of exopolysaccharide bioflocculant produced by heavy metal resistant Achromobacter xylosoxidans.

    PubMed

    Subudhi, Sanjukta; Bisht, Varsha; Batta, Neha; Pathak, Mihirjyoti; Devi, Arundhuti; Lal, Banwari

    2016-02-10

    Optimization of process parameters enhanced bioflocculating activity of 'Achromobacter xylosoxidans strain TERI L1' from 75% to 83.3% in absence of heavy metals, which decreased to 73% in presence of multi-metals. 'TERI L1' could adsorb 90% of multi-metals when grown in presence of 1250 mg L(-1) Zn, 2 mg L(-1) Cd, 30 mg L(-1) Pb, 200 mg L(-1) Ni and 90 mg L(-1) Cu and could adsorb 1100 mg L(-1) of Pb when grown in presence of 1500 ppm lead nitrate. The bioflocculant was purified and characterized. Bioflocculant yield was 5 g L(-1). Fourier transform infrared spectrum indicated presence of carboxyl, hydroxyl, amino groups, typical of glycoprotein. Spectroscopic analysis of bioflocculant by nuclear magnetic resonance revealed that it is a glycoprotein. LC-MS analysis confirmed the bioflocculant as a carbohydrate hetero polymer. Bioflocculant was composed of 75% total sugar with 72.9% neutral sugar and 11.5% protein. Scanning Electron Micrography revealed effective flocculation of kaolin clay by purified exopolysaccharide bioflocculant. PMID:26686149

  5. Order-fractal transitions in abstract paintings

    NASA Astrophysics Data System (ADS)

    de la Calleja, E. M.; Cervantes, F.; de la Calleja, J.

    2016-08-01

    In this study, we determined the degree of order for 22 Jackson Pollock paintings using the Hausdorff-Besicovitch fractal dimension. Based on the maximum value of each multi-fractal spectrum, the artworks were classified according to the year in which they were painted. It has been reported that Pollock's paintings are fractal and that this feature was more evident in his later works. However, our results show that the fractal dimension of these paintings ranges among values close to two. We characterize this behavior as a fractal-order transition. Based on the study of disorder-order transition in physical systems, we interpreted the fractal-order transition via the dark paint strokes in Pollock's paintings as structured lines that follow a power law measured by the fractal dimension. We determined self-similarity in specific paintings, thereby demonstrating an important dependence on the scale of observations. We also characterized the fractal spectrum for the painting entitled Teri's Find. We obtained similar spectra for Teri's Find and Number 5, thereby suggesting that the fractal dimension cannot be rejected completely as a quantitative parameter for authenticating these artworks.

  6. Short synthetic oligodeoxyribonucleotide leader sequences enhance accumulation of human proinsulin synthesized in Escherichia coli.

    PubMed Central

    Sung, W L; Yao, F L; Zahab, D M; Narang, S A

    1986-01-01

    Enhanced accumulation of human proinsulin synthesized in Escherichia coli has been achieved by inserting a short leader of homooligopeptide at the amino end of proinsulin. Out of 20 amino acid oligomers studied, (Ala)6, (Asn)6, (Cys)7, (Gln)7, (His)6, (Ser)6, and (Thr)6 leaders were the most effective, with the yield of proinsulin ranging between 6% and 26% of the total bacterial protein. These constructions were made by inserting a synthetic oligodeoxyribonucleotide duplex, coding for a small homooligopeptide, between a synthetic proinsulin gene and an eight-codon beta-galactosidase gene residue in vector pUC8. Cyanogen bromide cleavage of the 102 amino acid fused polypeptide yielded a species identical to authentic proinsulin, as judged by NaDodSO4/PAGE and radioimmunoassay. Images PMID:3511472

  7. Characteristic molecular vibrations of adenosine receptor ligands.

    PubMed

    Chee, Hyun Keun; Yang, Jin-San; Joung, Je-Gun; Zhang, Byoung-Tak; Oh, S June

    2015-02-13

    Although the regulation of membrane receptor activation is known to be crucial for molecular signal transduction, the molecular mechanism underlying receptor activation is not fully elucidated. Here we study the physicochemical nature of membrane receptor behavior by investigating the characteristic molecular vibrations of receptor ligands using computational chemistry and informatics methods. By using information gain, t-tests, and support vector machines, we have identified highly informative features of adenosine receptor (AdoR) ligand and corresponding functional amino acid residues such as Asn (6.55) of AdoR that has informative significance and is indispensable for ligand recognition of AdoRs. These findings may provide new perspectives and insights into the fundamental mechanism of class A G protein-coupled receptor activation. PMID:25622891

  8. (Collaborative coal project between the USA and India)

    SciTech Connect

    Krishnan, R.P.

    1990-10-05

    Under the Phase II, Alternative Energy Resources Development (AERD) project of the United States Agency for International Development (USAID) and the Government of India (GOI), five collaborative coal projects have been initiated in the areas of: (1) NO{sub x}/SO{sub x} control from coal-fired power plants, (2) slagging combustor development for high-ash Indian coals, (3) characterization of Indian coals for combustion and gasification. (4) diagnostic studies for prediction of power plant life expectancy, and (5) environmental and natural resource analysis of coal cycle. The Pittsburgh Energy Technology Center (PETC) has the implementation responsibility for these projects. The Indian collaborative institutions identified for these projects are the Bharat Heavy Electricals Ltd. (BHEL), Trichy, (projects 1--4), and the Tata Energy Research Institute (TERI) for project 5. The Oak Ridge National Laboratory (ORNL) is providing cross-cut technical coordination and support for these five projects.

  9. It's not about energy--it's about power!

    PubMed

    Blanton, Teri

    2014-01-01

    Teri Blanton is a former chairperson and current fellow at Kentuckians for the Commonwealth, a statewide organization that works "for a new balance of power and a just society aimed at changing unfair political, economic, and social systems." In March 2014 she was a keynote speaker addressing the annual conference of the Toxics Action Center in Boston, Massachusetts. We are publishing her speech, presented to the many environmental activists from community- and labor-based organizations that work on state and regional concerns. Ms. Blanton energized the conference with her message of persistent organizing to attain justice against the threats posed to our communities, health, and environment by powerful forces who exploit our lives and labor for their profit and power. She calls upon us to build the power to make the transition to more sustainable and democratic human development. PMID:25085832

  10. Amenities: a "touch of home" away from home.

    PubMed

    Unsworth, T E

    1988-08-01

    Amenities have come a long way from the simple bar of soap and little plastic bottle of shampoo that awaited each new arrival in most hotel and motel rooms. They are now a virtual necessity and important marketing tool for both the hospitality and health care fields. The variety of amenities is also increasing, with everything from bathrobes to blow dryers becoming available in different areas. The term "amenities" also now applies to more conceptual and intangible items; the things you can see and hear, as well as use to wash your hair. Teri E. Unsworth is vice president of market development with Guest Supply Inc., headquartered in North Brunswick, N.J., which is one of the largest manufacturers and suppliers of amenities in the nation. Ms. Unsworth discussed with Executive Housekeeping TODAY the changing role and varieties of amenities in the marketplace today. PMID:10288501

  11. Report on marine mammal stranding

    NASA Astrophysics Data System (ADS)

    Kumar, Mohi

    2006-06-01

    The U.S. National Oceanic and Atmospheric Administration (NOAA) released a report on 27 April indicating that U.S. Navy sonar transmissions may have played a role in the stranding of more than 150 melon-headed whales on 3 July 2004 off the coast of Kauai, Hawaii. At the time of the stranding, which resulted in one whale death, the Navy was preparing to conduct sonar activities as part of a military exercise. The report notes that six naval surface vessels transiting to the area on the previous night intermittenly transmitted mid-frequency active sonar. That activity is ``a plausible, if not likely, contributing factor'' to the stranding event. There was no significant weather, natural oceanographic event, or known biological factors that would explain the animals' movement into the bay nor the group's continued presence in the bay, according to report lead author Teri Rowles, NOAA marine mammal veterinarian.

  12. A replica of the Olympic torch is recovered from STS-101 Atlantis

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Teri McKinney, with Shuttle Crew Escape, Johnson Space Center, holds a replica of the Olympic torch carried aboard Space Shuttle Atlantis on mission STS-101. The addition of the torch to the payload was coordinated by astronaut Andy Thomas, who is from Australia. The torch will travel to Australia for the 2000 Olympic games being held there in September. . STS-101 was the third flight to the International Space Station and included repairs to the Station plus transfer of equipment and supplies to the Station for future missions. The landing of Atlantis completed a 9-day, 20-hour, 9-minute-long mission. It was the 98th flight in the Space Shuttle program and the 21st for Atlantis. The landing was the 51st at KSC, the 22nd consecutive landing at KSC, the 14th nighttime landing in Shuttle history and the 29th in the last 30 Shuttle flights.

  13. Emissions of SO2 and NOx from biofuels in India

    NASA Astrophysics Data System (ADS)

    Gadi, Ranu; Kulshrestha, U. C.; Sarkar, A. K.; Garg, S. C.; Parashar, D. C.

    2003-07-01

    Concentrations of oxides of S and N in the atmosphere are strongly influenced by the emissions taking place from the burning of biofuels. This is particularly important in the developing countries where most of the energy requirement in the rural sector is met from biofuels. An experimental setup has been built to carry out controlled biomass burning and to derive emission factors for SO2 and NOx (NO and NO2) from various biofuels commonly used in India. Using these emission factors and the consumption data obtained from Tata Energy Research Institute's (TERI) Energy Data Directory and Yearbook 1998-99, the budget of SO2 and NOx from biofuels used in India has been estimated as 0.4 ± 0.3 and 1.0 ± 0.4 Tg, respectively, for the year 1990.

  14. Influence of headspace composition on product diversity by sulphate reducing bacteria biocathode.

    PubMed

    Sharma, Mohita; Varanasi, Jhansi L; Jain, Pratiksha; Dureja, Prem; Lal, Banwari; Dominguez-Benetton, Xochitl; Pant, Deepak; Sarma, Priyangshu M

    2014-08-01

    Mixed culture of sulphate reducing bacteria named TERI-MS-003 was used for development of biocathode on activated carbon fabric fastened to stainless steel mesh for conversion of volatile fatty acids to reduced organic compounds under chronoamperometric conditions of -0.85V vs. Ag/AgCl (3.5M KCl). A range of chemicals were bioelectrosynthesized, however the gases present in headspace environment of the bioelectrochemical reactor governed the product profile. Succinate, ethanol, hydrogen, glycerol and propionate were observed to be the predominant products when the reactor was hermetically sealed. On the other hand, acetone, propionate, isopropanol, propanol, isobutyrate, isovalerate and heptanoate were the predominant products when the reactor was continuously sparged with nitrogen. This study highlights the importance of head space composition in order to manoeuvre the final product profile desired during a microbial electro-synthesis operation and the need for simultaneously developing effective separation and recovery strategies from an economical and practical standpoint. PMID:24726774

  15. ISCR Elements: Novel Gene-Capturing Systems of the 21st Century?

    PubMed Central

    Toleman, Mark A.; Bennett, Peter M.; Walsh, Timothy R.

    2006-01-01

    “Common regions” (CRs), such as Orf513, are being increasingly linked to mega-antibiotic-resistant regions. While their overall nucleotide sequences show little identity to other mobile elements, amino acid alignments indicate that they possess the key motifs of IS91-like elements, which have been linked to the mobility ent plasmids in pathogenic Escherichia coli. Further inspection reveals that they possess an IS91-like origin of replication and termination sites (terIS), and therefore CRs probably transpose via a rolling-circle replication mechanism. Accordingly, in this review we have renamed CRs as ISCRs to give a more accurate reflection of their functional properties. The genetic context surrounding ISCRs indicates that they can procure 5′ sequences via misreading of the cognate terIS, i.e., “unchecked transposition.” Clinically, the most worrying aspect of ISCRs is that they are increasingly being linked with more potent examples of resistance, i.e., metallo-β-lactamases in Pseudomonas aeruginosa and co-trimoxazole resistance in Stenotrophomonas maltophilia. Furthermore, if ISCR elements do move via “unchecked RC transposition,” as has been speculated for ISCR1, then this mechanism provides antibiotic resistance genes with a highly mobile genetic vehicle that could greatly exceed the effects of previously reported mobile genetic mechanisms. It has been hypothesized that bacteria will surprise us by extending their “genetic construction kit” to procure and evince additional DNA and, therefore, antibiotic resistance genes. It appears that ISCR elements have now firmly established themselves within that regimen. PMID:16760305

  16. Synthetic peptide derived from alpha-fetoprotein inhibits growth of human breast cancer: investigation of the pharmacophore and synthesis optimization.

    PubMed

    DeFreest, L A; Mesfin, F B; Joseph, L; McLeod, D J; Stallmer, A; Reddy, S; Balulad, S S; Jacobson, H I; Andersen, T T; Bennett, J A

    2004-05-01

    Pro4 is not essential. Valine (Val5) can be substituted only with branched-chain amino acids (isoleucine, leucine or Thr); replacement by d-valine or Ala resulted in loss of biologic activity. Thus, for this site, the bulky branched side chain is essential. Asparagine (Asn6) is essential for activity. Substitution with Gln or aspartic acid (Asp), resulted in reduction of biologic activity. Removal of glycine (Gly8) resulted in a loss of activity but nonconservative substitutions can be made at this site without a loss of activity indicating that it is not part of the pharmacophore. Cyclization of the peptide is facilitated by addition of Gln9, but this residue does not occur in AFP nor is it necessary for activity. Gln9 can be replaced with Asn, resulting in a molecule with similar activity. These data indicate that the pharmacophore of the peptide includes side chains of Val5 and Asn6 and backbone atoms contributed by Thr3, Val5, Asn6, Hyp7 and Gly8. Met2 and Gln9 can be modified or replaced. Glu1 can be replaced with charged amino acids, and is not likely to be part of the binding site of the peptide. The results of this study provide information that will be helpful in the rational modification of cyclo[EMTOVNOGQ] to yield peptide analogs and peptidomimetics with advantages in synthesis, pharmacologic properties, and biologic activity. PMID:15140158

  17. Discovery of potent hexapeptide agonists to human neuromedin u receptor 1 and identification of their serum metabolites.

    PubMed

    Takayama, Kentaro; Mori, Kenji; Sohma, Yuko; Taketa, Koji; Taguchi, Akihiro; Yakushiji, Fumika; Minamino, Naoto; Miyazato, Mikiya; Kangawa, Kenji; Hayashi, Yoshio

    2015-03-12

    Neuromedin U (NMU) and S (NMS) display various physiological activities, including an anorexigenic effect, and share a common C-terminal heptapeptide-amide sequence that is necessary to activate two NMU receptors (NMUR1 and NMUR2). On the basis of this knowledge, we recently developed hexapeptide agonists 2 and 3, which are highly selective to human NMUR1 and NMUR2, respectively. However, the agonists are still less potent than the endogenous ligand, hNMU. Therefore, we performed an additional structure-activity relationship study, which led to the identification of the more potent hexapeptide 5d that exhibits similar NMUR1-agonistic activity as compared to hNMU. Additionally, we studied the stability of synthesized agonists, including 5d, in rat serum, and identified two major biodegradation sites: Phe(2)-Arg(3) and Arg(5)-Asn(6). The latter was more predominantly cleaved than the former. Moreover, substitution with 4-fluorophenylalanine, as in 5d, enhanced the metabolic stability at Phe(2)-Arg(3). These results provide important information to guide the development of practical hNMU agonists. PMID:25815150

  18. Molten carbonate fuel cells for power generation from high-ash Indian coals

    SciTech Connect

    Perumal, R.; Bali, S.; Balakrishnan, M.; Mathur, A.

    1997-12-31

    The recently completed first phase of the study on MCFC at TERI involved the development of a laboratory-scale MCFC single cell, testing its performance with simulated coal gas mixtures and the development of a mathematical model for the purpose of estimating the material and energy requirements of an integrated coal gasification-MCFC (IG-MCFC) system. The results obtained from the monocell indicate that the drop in performance while using simulated coal gas as compared to that using pure hydrogen as the fuel is nominal. Moreover, the efficiency levels predicted by the model indicate that IG-MCFC systems would be attractive for the Indian power sector, as over 60% of the power generation in India is coal-based. The second phase of this work, which is underway and scheduled to be completed by mid-1998, involves the development of a kilowatt level MCFC stack for continued testing with simulated coal gas. The third phase would comprise of field demonstration of a 5--10 kW MCFC stack coupled to an experimental gasifier.

  19. Structural Characterization of ISCR8, ISCR22, and ISCR23, Subgroups of IS91-Like Insertion Elements ▿

    PubMed Central

    Schleinitz, Kathleen M.; Vallaeys, Tatiana; Kleinsteuber, Sabine

    2010-01-01

    Analysis of ISCR8 (ISPps1) revealed that this group of insertion elements has to be subdivided into three subgroups: ISCR8, ISCR22, and ISCR23. The distinction of three subgroups is supported by phylogenetic analysis of the transposase open reading frames (ORFs). Comparison of over 20 complete and partial ISCR8/22/23 elements identified oriIS candidate sequences for all groups and a terIS candidate sequence for ISCR8. The oriIS sequences, their distance to the transposase ORFs, and the sequence of this intervening region are group specific, further supporting the definition of two new ISCR elements. ISCR8/22/23 have a very broad host range, including Gram-positive and Gram-negative bacteria, among which are several (opportunistic) pathogens. The IS often resides on plasmids or in the vicinity of other mobile elements and is mostly associated with genes for the degradation of halo- or nitro-aromatics. However, in one case ISCR8 was found in the neighborhood of an antibiotic resistance determinant in Klebsiella pneumoniae. ISCR8 resembles other IS91 family elements in mediating genetic rearrangements by homologous recombination between two copies. In Delftia acidovorans this led to the loss of the genes encoding dichlorprop cleavage. In conclusion, this study shows that ISCR8 could be a fully functional and active member of the IS91 family of insertion elements. PMID:20625149

  20. Endoscopic therapy for weight loss: Gastroplasty, duodenal sleeves, intragastric balloons, and aspiration

    PubMed Central

    Kumar, Nitin

    2015-01-01

    A new paradigm in the treatment of obesity and metabolic disease is developing. The global obesity epidemic continues to expand despite the availability of diet and lifestyle counseling, pharmacologic therapy, and weight loss surgery. Endoscopic procedures have the potential to bridge the gap between medical therapy and surgery. Current primary endoscopic bariatric therapies can be classified as restrictive, bypass, space-occupying, or aspiration therapy. Restrictive procedures include the USGI Primary Obesity Surgery Endolumenal procedure, endoscopic sleeve gastroplasty using Apollo OverStitch, TransOral GAstroplasty, gastric volume reduction using the ACE stapler, and insertion of the TERIS restrictive device. Intestinal bypass has been reported using the EndoBarrier duodenal-jejunal bypass liner. A number of space-occupying devices have been studied or are in use, including intragastric balloons (Orbera, Reshape Duo, Heliosphere BAG, Obalon), Transpyloric Shuttle, and SatiSphere. The AspireAssist aspiration system has demonstrated efficacy. Finally, endoscopic revision of gastric bypass to address weight regain has been studied using Apollo OverStitch, the USGI Incisionless Operating Platform Revision Obesity Surgery Endolumenal procedure, Stomaphyx, and endoscopic sclerotherapy. Endoscopic therapies for weight loss are potentially reversible, repeatable, less invasive, and lower cost than various medical and surgical alternatives. Given the variety of devices under development, in clinical trials, and currently in use, patients will have multiple endoscopic options with greater efficacy than medical therapy, and with lower invasiveness and greater accessibility than surgery. PMID:26240686

  1. Endoscopic therapy for weight loss: Gastroplasty, duodenal sleeves, intragastric balloons, and aspiration.

    PubMed

    Kumar, Nitin

    2015-07-25

    A new paradigm in the treatment of obesity and metabolic disease is developing. The global obesity epidemic continues to expand despite the availability of diet and lifestyle counseling, pharmacologic therapy, and weight loss surgery. Endoscopic procedures have the potential to bridge the gap between medical therapy and surgery. Current primary endoscopic bariatric therapies can be classified as restrictive, bypass, space-occupying, or aspiration therapy. Restrictive procedures include the USGI Primary Obesity Surgery Endolumenal procedure, endoscopic sleeve gastroplasty using Apollo OverStitch, TransOral GAstroplasty, gastric volume reduction using the ACE stapler, and insertion of the TERIS restrictive device. Intestinal bypass has been reported using the EndoBarrier duodenal-jejunal bypass liner. A number of space-occupying devices have been studied or are in use, including intragastric balloons (Orbera, Reshape Duo, Heliosphere BAG, Obalon), Transpyloric Shuttle, and SatiSphere. The AspireAssist aspiration system has demonstrated efficacy. Finally, endoscopic revision of gastric bypass to address weight regain has been studied using Apollo OverStitch, the USGI Incisionless Operating Platform Revision Obesity Surgery Endolumenal procedure, Stomaphyx, and endoscopic sclerotherapy. Endoscopic therapies for weight loss are potentially reversible, repeatable, less invasive, and lower cost than various medical and surgical alternatives. Given the variety of devices under development, in clinical trials, and currently in use, patients will have multiple endoscopic options with greater efficacy than medical therapy, and with lower invasiveness and greater accessibility than surgery. PMID:26240686

  2. Pancreatic Polypeptide Is Recognized by Two Hydrophobic Domains of the Human Y4 Receptor Binding Pocket*

    PubMed Central

    Pedragosa-Badia, Xavier; Sliwoski, Gregory R.; Dong Nguyen, Elizabeth; Lindner, Diana; Stichel, Jan; Kaufmann, Kristian W.; Meiler, Jens; Beck-Sickinger, Annette G.

    2014-01-01

    Structural characterization of the human Y4 receptor (hY4R) interaction with human pancreatic polypeptide (hPP) is crucial, not only for understanding its biological function but also for testing treatment strategies for obesity that target this interaction. Here, the interaction of receptor mutants with pancreatic polypeptide analogs was studied through double-cycle mutagenesis. To guide mutagenesis and interpret results, a three-dimensional comparative model of the hY4R-hPP complex was constructed based on all available class A G protein-coupled receptor crystal structures and refined using experimental data. Our study reveals that residues of the hPP and the hY4R form a complex network consisting of ionic interactions, hydrophobic interactions, and hydrogen binding. Residues Tyr2.64, Asp2.68, Asn6.55, Asn7.32, and Phe7.35 of Y4R are found to be important in receptor activation by hPP. Specifically, Tyr2.64 interacts with Tyr27 of hPP through hydrophobic contacts. Asn7.32 is affected by modifications on position Arg33 of hPP, suggesting a hydrogen bond between these two residues. Likewise, we find that Phe7.35 is affected by modifications of hPP at positions 33 and 36, indicating interactions between these three amino acids. Taken together, we demonstrate that the top of transmembrane helix 2 (TM2) and the top of transmembrane helices 6 and 7 (TM6–TM7) form the core of the peptide binding pocket. These findings will contribute to the rational design of ligands that bind the receptor more effectively to produce an enhanced agonistic or antagonistic effect. PMID:24375409

  3. Immunosuppressive drugs and fertility.

    PubMed

    Leroy, Clara; Rigot, Jean-Marc; Leroy, Maryse; Decanter, Christine; Le Mapihan, Kristell; Parent, Anne-Sophie; Le Guillou, Anne-Claire; Yakoub-Agha, Ibrahim; Dharancy, Sébastien; Noel, Christian; Vantyghem, Marie-Christine

    2015-01-01

    Immunosuppressive drugs are used in the treatment of inflammatory and autoimmune diseases, as well as in transplantation. Frequently prescribed in young people, these treatments may have deleterious effects on fertility, pregnancy outcomes and the unborn child. This review aims to summarize the main gonadal side effects of immunosuppressants, to detail the effects on fertility and pregnancy of each class of drug, and to provide recommendations on the management of patients who are seen prior to starting or who are already receiving immunosuppressive treatment, allowing them in due course to bear children. The recommendations for use are established with a rather low level of proof, which needs to be taken into account in the patient management. Methotrexate, mycophenolate, and le- and teri-flunomide, cyclophosphamide, mitoxanthrone are contraindicated if pregnancy is desired due to their teratogenic effects, as well as gonadotoxic effects in the case of cyclophosphamide. Anti-TNF-alpha and mTOR-inhibitors are to be used cautiously if pregnancy is desired, since experience using these drugs is still relatively scarce. Azathioprine, glucocorticoids, mesalazine, anticalcineurins such as cyclosporine and tacrolimus, ß-interferon, glatiramer-acetate and chloroquine can be used during pregnancy, bearing in mind however that side effects may still occur. Experience is limited concerning natalizumab, fingolimod, dimethyl-fumarate and induction treatments. Conclusion: At the time of prescription, patients must be informed of the possible consequences of immunosuppressants on fertility and of the need for contraception. Pregnancy must be planned and the treatment modified if necessary in a pre-conception time period adapted to the half-life of the drug, imperatively in relation with the prescriber of the immunosuppressive drugs. PMID:26490561

  4. LDEF (Postflight), S1001 : Low-Temperature Heat Pipe Experiment Package (HEPP) for LDEF, Tray H01

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The postflight photograph of the Low Tem perature Heat Pipe Package (HEPP) power tray was taken in the SAEF II at KSC after an all up system checkout with interfacing experiments and removal of the tray from the LDEF. An outline of the experiment tray clamp blocks is clearly visible in the light brown stain on the experiment tray flanges. The Low Temperature Heat Pipe Package (HEPP) experiment occupies two 12 inch deep LDEF experiment trays connected with an inter-tray wiring harness. The HEPP Power tray, an end cor ner tray, occupies a location on the space end of the LDEF in tray location H01 and the HEPP Experiment tray, a peripheral tray, is located in the LDEF tray location F12. The power tray (H01) consist of four solar array panels, one nickel-cadmium (NiCd) battery, a Power System Electronics (PSE) unit, protective thermal blankets that line the tray interior and a thirty seven pound baseplate mounted on thermal isolators to provide a thermally stable mounting for the bat tery and the PSE. Thirteen strips of thin film thermal control materials, part of an experiment by NASA GSFC that consist of sixty-five samples located at three different LDEF tray locations (H01, F09 and F12), were attached to the experiment tray flanges with Kapton tape. The experi ment was assembled and mounted in the experiment tray with non-magnetic stainless steel fasten ers. The experiment hardware appears to be intact with no apparent changes other than stains along outer edges of the solar arrays. The light brown stains observed along the upper edges of the solar array mounting plates and around the outer edge of the baseplate in the flight photograph are not apparent in the postflight photo. The atomic oxygen experiment thin film strips appear to be in place with no apparent damage. The Kapton tape appears to be firmly adhered to the tray flanges in all thirteen locations.

  5. Prophylaxis and Treatment of Anthrax in Pregnant Women: A Systematic Review of Antibiotics

    PubMed Central

    Meaney-Delman, Dana; Rasmussen, Sonja A.; Beigi, Richard H.; Zotti, Marianne E.; Hutchings, Yalonda; Bower, William A.; Treadwell, Tracee A.; Jamieson, Denise J.

    2016-01-01

    Objective To review the safety and pharmacokinetics of antibiotics recommended for anthrax post-exposure prophylaxis and treatment in pregnant women. Data Sources Articles were identified in the PUBMED database from inception through December 2012 by searching the keywords ([“pregnancy]” and [generic antibiotic name]). Additionally, hand searches of references from REPROTOX, TERIS, review articles and Briggs’ Drugs in Pregnancy and Lactation were performed. Methods of Study Selection Articles included in the review contain primary data related to the safety and pharmacokinetics among pregnant women of five antibiotics recommended for anthrax post-exposure prophylaxis and treatment (ciprofloxacin, levofloxacin, moxifloxacin, doxycycline, amoxicillin), and of nine additional antibiotics recommended as part of the treatment regimen (penicillin, ampicillin, linezolid, clindamycin, meropenem, doripenem, rifampin, chloramphenicol, or vancomycin). Tabulation, Integration and Results The PUBMED search identified 3850 articles for review. Reference hand searching yielded nine additional articles. In total, 112 articles met the inclusion criteria. Conclusions Overall, safety and pharmacokinetic information is limited for these antibiotics. Although small increases in risks for certain anomalies have been observed with some antibiotics recommended for prophylaxis and treatment of anthrax, the absolute risk of these antibiotics appears low. Given the high morbidity and mortality associated with anthrax, antibiotics should be dosed appropriately to ensure that antibiotic levels can be achieved and sustained. Dosing adjustments may be necessary for the beta lactam antibiotics and the fluoroquinolones to achieve therapeutic levels in pregnant women. Data indicate that the beta lactam antibiotics, the fluoroquinolones, and, to a lesser extent, clindamycin enter the fetal compartment, an important consideration in the treatment of anthrax, as these antibiotics may provide

  6. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene.

    PubMed

    Venugopal, R; Jaiswal, A K

    1996-12-10

    Twenty-four base pairs of the human antioxidant response element (hARE) are required for high basal transcription of the NAD(P)H:quinone oxidoreductase1 (NQO1) gene and its induction in response to xenobiotics and antioxidants. hARE is a unique cis-element that contains one perfect and one imperfect AP1 element arranged as inverse repeats separated by 3 bp, followed by a "GC" box. We report here that Jun, Fos, Fra, and Nrf nuclear transcription factors bind to the hARE. Overexpression of cDNA derived combinations of the nuclear proteins Jun and Fos or Jun and Fra1 repressed hARE-mediated chloramphenicol acetyltransferase (CAT) gene expression in transfected human hepatoblastoma (Hep-G2) cells. Further experiments suggested that this repression was due to overexpression of c-Fos and Fra1, but not due to Jun proteins. The Jun (c-Jun, Jun-B, and Jun-D) proteins in all the possible combinations were more or less ineffective in repression or upregulation of hARE-mediated gene expression. Interestingly, overexpression of Nrf1 and Nrf2 individually in Hep-G2 and monkey kidney (COS1) cells significantly increased CAT gene expression from reporter plasmid hARE-thymidine kinase-CAT in transfected cells that were inducible by beta-naphthoflavone and teri-butyl hydroquinone. These results indicated that hARE-mediated expression of the NQO1 gene and its induction by xenobiotics and antioxidants are mediated by Nrf1 and Nrf2. The hARE-mediated basal expression, however, is repressed by overexpression of c-Fos and Fra1. PMID:8962164

  7. LDEF (Postflight), S1001 : Low-Temperature Heat Pipe Experiment Package (HEPP) for LDEF, Tray H01

    NASA Technical Reports Server (NTRS)

    1990-01-01

    LDEF (Postflight), S1001 : Low-Temperature Heat Pipe Experiment Package (HEPP) for LDEF, Tray H01 The post landing photograph of the Low Tempera ture Heat Pipe Package (HEPP) experiment was taken from the Orbiter's cargo bay access hatch during post landing operations to prepare the Orbiter for the ferry flight from the Dryden Flight Research Center to the Kennedy Space Center. The white paint dots on the center clamp blocks of the experiment trays right flange and upperer flange appear to be discolored. The discoloration diminishes as as the distance from the vent area of the thermal shields increases. The right and upper tray flanges also appear to be discolored. Finger prints are visible on the thermal panels in the vicinity of the panel mounting fasteners. The Low Temperature Heat Pipe Package (HEPP) experiment occupies two 12 inch deep LDEF experiment trays connected with an inter-tray wiring harness. The HEPP Power tray, an end cor ner tray, occupies a location on the space end of the LDEF in tray location H01 and the HEPP Experiment tray, a peripheral tray, is located in the LDEF tray location F12. The power tray (H01) consist of four solar array panels, one nickel-cadmium (NiCd) battery, a Power System Electronics (PSE) unit, protective thermal blankets that line the tray interior and a thirty seven pound baseplate mounted on thermal isolators to provide a thermally stable mounting for the bat tery and the PSE.. Thirteen strips of thin film thermal control materials, part of an experiment by NASA GSFC that consist of sixty-five samples located at three different LDEF tray locations (H01, F09 and F12), were attached to the experiment tray flanges with Kapton tape. The experi ment was assembled and mounted in the experiment tray with non-magnetic stainless steel fasten ers. The experiment hardware appears to be intact with no apparent changes other than stains along outer edges of the solar arrays. Light brown stains are visible along the upper edges of the

  8. LDEF (Flight), S1001 : Low-Temperature Heat Pipe Experiment Package (HEPP) for LDEF, Tray H01

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The flight photograph of the Low Temperature Heat Pipe Package (HEPP) experiment was taken while the LDEF was attached to the Orbiter's RMS arm prior to berthing in the Orbiter's cargo bay. The white paint dots on the center clamp blocks of the experiment trays right flange and lower flange appear to be discolored. The discolor ation diminishes as as the distance from the vent area of the thermal shields increases. The right and lower tray flanges also appear to be discolored. Finger prints are visible on the thermal panels in the vicinity of the panel mounting fasteners. The Low Temperature Heat Pipe Package (HEPP) experiment occupies two 12 inch deep LDEF experiment trays connected with an inter-tray wiring harness. The HEPP Power tray, an end cor ner tray, occupies a location on the space end of the LDEF in tray location H01 and the HEPP Experiment tray, a peripheral tray, is located in the LDEF tray location F12. The power tray (H01) consist of four solar array panels, one nickel-cadmium (NiCd) battery, a Power System Electronics (PSE) unit, protective thermal blankets that line the tray interior and a thirty seven pound baseplate mounted on thermal isolators to provide a thermally stable mounting for the bat tery and the PSE. Thirteen strips of thin film thermal control materials, part of an experiment by NASA GSFC that consist of sixty-five samples located at three different LDEF tray locations (H01, F09 and F12), were attached to the experiment tray flanges with Kapton tape. The experi ment was assembled and mounted in the experiment tray with non-magnetic stainless steel fasten ers. The experiment hardware appears to be intact with no apparent changes other than stains along outer edges of the solar arrays. Light brown stains are visible along the upper edges of the solar array mounting plates with faint traces of a lighter colored stain around the outer edge of the base plate. The atomic oxygen experiment thin film strips appear to be in place with no

  9. GRAIL Gravity Observations of Lunar Volcanic Complexes

    NASA Astrophysics Data System (ADS)

    Kiefer, W. S.; Zuber, M. T.; McGovern, P. J.; Head, J. W.

    2012-12-01

    Gravity observations by NASA's GRAIL mission are providing important new insights into the volcanic plumbing associated with major volcanic complexes on the Moon. The Marius Hills are the Moon's largest volcanic dome field, consisting of more than 250 basaltic domes and cones and 20 sinuous rilles. There are two distinct free-air gravity anomalies, with the larger anomaly (260 mGal) occurring close to the maximum concentration of volcanic domes in the northern part of the field. Much of the gravity anomaly in this area is due to buried, high density material, mapping out a sill complex with a spatial scale of 200 by 250 kilometers. For plausible choices of density contrast, the sill is more than 2 km thick in the north and 4 km thick in the south. The Aristarchus Plateau is the source for the Moon's largest pyroclastic eruption and numerous sinuous rilles. Most of the gravity anomaly on the plateau itself has relatively low amplitude (< 60 mGal) and is likely due to isostatic or flexurally supported topography. There is a significant gravity high (160 mGal) associated with the Cobra Head, which is the source region for Vallis Schröteri, the largest rille in the Aristarchus Plateau. Regions of high free-air gravity also occur in the plains wrapping around the south and east sides of the plateau and in the adjacent Harbinger Mountains/Prinz Crater volcanic field (150 mGal). These gravity highs are all likely due to buried, high density material, plausibly in the form of volcanic intrusions. The Cauchy volcanic dome complex in eastern Mare Tranquillitatis is a regional topographic high about 400 km across but a free-air gravity low (-90 mGal). Similarly, the Hortensius/Tobias Mayer volcanic field in Mare Insularum is also a free-air gravity low (-80 mGal) in its center. In both cases, this implies the presence of low density material at depth, possibly due to thicker than normal crust. The Rümker Hills in northern Oceanus Procellarum is a small basaltic dome complex

  10. Realities of weather extremes on daily life in urban India - How quantified impacts infer sensible adaptation options

    NASA Astrophysics Data System (ADS)

    Reckien, D.

    2012-12-01

    when resources are scarce. 1 Parry ML, Canziani OF, Palutikof JP, van der Linden PJ, Hanson CE (eds) (2007) Contribution of Working Group II to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change. Cambridge University Press, Cambridge New York. 2 TERI (2007) Adaptation to Climate Change in the context of Sustainable Development. Background Paper to the conference ''Climate Change and Sustainable Development: An international workshop to strengthen research and understanding'', 7-8 April 2006, The Energy and Resources Institute, New Delhi.

  11. Quaternary Tectonics of The Vitosha Mountain (bulgaria)

    NASA Astrophysics Data System (ADS)

    Angelova, Dora

    The Vitosha Mt. is a Cretaceous paleovolcano of the central type with complex ge- ological evolution. From a contemporary point of view it has a marked orographic homogeneity, which is connected with its specific evolution during the Neogene and the Quaternary. At the background of intensive vault formation, graben systems from the Maritsa and Strouma fault zones originated in a sharp discordance along its pe- riphery. The vault formation process caused the accumulation of tectonic stresses in different parts of the Vitosha Mt. in the course of time and space. The tectonic stresses provoked the formation of concentric normal faults. Their surface display predeter- mined not only the block disintegration of the structure but also its primary relief. The active mountain formation of Vitosha was controlled by the Pernik and Vladaya fault zones, and by the Vitosha, Zheleznitsa, Matnitsa and Chuipetlovo fault beams during the Quaternary. The Pliocene-Pleistocene boundary was accompanied by active ver- tical tectonic deformations. As a result of pulse tectonic movements and subsequent deformations along the above mentioned structures, a global re-arrangement of the Vladaiska and Strouma River basins took place in the region of the Vladaya village and to the south of the Chuipetlovo village. The age of these events is 0.73 Ma. The pa- leoseismic dislocation in the region of the Dragalevtsi quarter was probably formed at the same time. The paleoseismic deformations during the Middle Pleistocene were es- tablished along the radial faults. They had caused rock-falls in the Douhlata cave, pyra- teries and bifurcations of the underground aquatic system and of the Klisuritsa River. The Holocene stage was characterised by intensified vertical movements along all fault structures together with the climatic changes under post-glacial circumstances. The Vitosha paleovolcano was mightily raised due to the vertical compression and new river system originated while the old one was

  12. Stress field modelling from digital geological map data

    NASA Astrophysics Data System (ADS)

    Albert, Gáspár; Barancsuk, Ádám; Szentpéteri, Krisztián

    2016-04-01

    calculated from the fracture criterion. The calculation includes the gravitational acceleration, the average density of rocks and the experimental 60 degree of the fracture angle from the normal of the fault plane. This way, the stress tensors are calculated as absolute pressure values per square meters on both sides of the faults. If the stress from the overburden is greater than 1 bar (i.e. the faults are buried), a confined compression would be present. Modelling this state of stress may result a confusing pattern of vectors, because in a confined position the horizontal stress vectors may point towards structures primarily associated with extension. To step over this, and to highlight the variability in the stress-field, the model calculates the vectors directly from the differential stress (practically subtracting the minimum principal stress from the critical stress). The result of the modelling is a vector map, which theoretically represents the minimum tectonic pressure in the moment, when the rock body breaks from an initial state. This map - together with the original fault-map - is suitable for determining those areas where unrevealed tectonic, sedimentary and lithological structures are possibly present (e.g. faults, sub-basins and intrusions). With modelling different deformational phases on the same area, change of the stress vectors can be detected which reveals not only the varying directions of the principal stresses, but the tectonic-driven sedimentation patterns too. The decrease of necessary critical stress in the case of a possible reactivation of a fault in subsequent deformation phase can be managed with the down-ranking of the concerning structural elements. Reference: Albert G., Ungvári ZS., Szentpéteri K. 2014: Modeling the present day stress field of the Pannonian Basin from neotectonic maps - In: Beqiraj A, Ionescu C, Christofides G, Uta A, Beqiraj Goga E, Marku S (eds.) Proceedings XX Congress of the Carpathian-Balkan Geological Association

  13. Source quantification of size and season resolved aerosols in a semi-urban area of Indo-Gangetic plain, India

    NASA Astrophysics Data System (ADS)

    Hooda, R. K.; Hyvärinen, A.; Gilardoni, S.; Sharma, V.; Vestenius, M.; Kerminen, V.; Vignati, E.; Kulmala, M. T.; Lihavainen, H.

    2012-12-01

    This study describes a one year measurements of size-segregated aerosols at a semi-urban site in Indo-Gangetic plain (IGP), India, South Asia with focus on source quantification applied to organic and inorganic chemical species data using Positive Matrix Factorization (PMF), trajectory analysis and conditional probability function (CPF) methods. The campaign was planned in the framework of the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) project. In light of the above, Finnish Meteorological Institute (FMI), The Energy and Resources Institute (TERI) and Joint Research Centre (JRC) conducted aerosol mass measurements in Gual Pahari, India from April 2008 to March 2009. The average mass concentrations of fine (PM2.5) and coarse (PM2.5-10) aerosols are higher during the postmonsoon (October-November) and winter (December- February) compared to that during the summer season (March-May). Fine and coarse fraction concentrations observed are higher during the post-monsoon & winter months due to low and stable boundary layer. Concentrations decrease in March-June due to increasing temperatures and a higher boundary layer. The lowest concentrations are during the rainy months (June to August/Sept) due to wet removal. OC and EC fraction is higher in PM2.5. EC in in PM2.5 is 9%, and in PM2.5-10 size EC is 2%. OC contribution is about 36% of fine aerosol mass. High OC could be attributed to enhanced combustion sources and the meteorological conditions during winter period. High OC to EC ratio during postmonsoon and winter also supports higher secondary organic aerosol (SOA) formation in these seasons. Secondary organic carbon (SOC) calculated is 42% of the annual average of total OC in coarse fraction. SOC to total OC is highest in postmonsoon (53%), winter (34%) and followed by 29% in summer and monsoon seasons. 24-hr speciated fine and coarse aerosols annual data was used for source identification and quantification studies with

  14. Journal abstracts from current research in the field of child and adolescent mental health.

    PubMed

    2009-12-01

    Debate RD, Kelley PG, Zwald M, Huberty J & Zhang Y (2009) Changes in psychosocial factors and physical activity frequency among third- to eighth-grade girls who participated in a developmentally focused youth sport program: A preliminary study. Journal of School Health 79(10): 474-484 Boyce JC, Mueller NB, Hogan-Watts M & Luke Douglas A (2009) Evaluating the strength of school tobacco policies: The development of a practical rating system. Journal of School Health 79(10): 495-504 Craine JL, Tanaka Teri A, Nishina A & Conger KJ (2009) Understanding adolescent delinquency: The role of older siblings' delinquency and popularity with peers. Merrill-Palmer Quarterly 55(4): 436-453 Rosales FJ, Reznick JS & Zeisel SH (2009) Understanding the role of nutrition in the rain and behavioural development of toddlers and pre-school children: Identifying methodological barriers. Nutritional Neuroscience 12(5): 190-202 Clemmens DA (2009) The Significance of motherhood for adolescents whose mothers have breast cancer. Oncology Nursing Forum 36(5): 571-577 Archambault I, Janosz M, Morizot J & Pagani L (2009) Adolescent behavioural, affective, and cognitive engagement in school: Relationship to dropout. Journal of School Health 79(9): 408-415 Denison JA, McCauley AP, Dunnett-Dagg WA, Lungu N & Sweat MD (2009) HIV testing among adolescents in Ndola, Zambia: How individual, relational, and environmental factors relate to demand. AIDS Education & Prevention 21(4): 314-324 Pollock JA & Halkitis PN (2009) Environmental factors in relation to unprotected sexual behaviour among gay, bisexual and other MSM. AIDS Education & Prevention 21(4): 340-355 Nippold MA, Mansfield TC, Billow JL & Tomblin JB (2009) Syntactic development in adolescents with a history of language impairments: A follow-up investigation. American Journal of Speech-Language Pathology 18(3): 241-251 Sharaf AY, Thompson EA & Walsh E (2009) Protective effects of self-esteem and family support on suicide risk behaviours among

  15. New developments at Hunveyor and Husar space probe model constructions in Hungarian Universities and Colleges: status report of 2008

    NASA Astrophysics Data System (ADS)

    Hegzi, S.; Bérczi, Sz.; Hudoba, Gy.; Magyar, I.; Lang, A.; Istenes, Z.; Weidinger, T.; Tepliczky, I.; Varga, T.; Hargitai, H.

    2008-09-01

    Society developed the last Hunveyor system. It was a meteorological station with 14 measurements. It represents a halfway Hunveyor, because of the building together of the instruments can be studied in this system. It was transported by the Crew 71 to the MDRS and two weeks of measurements were carried out in Utah, during 2008 April (with Husar-2d field work, too). Summary Several new developments of the Hunveyor-Husar university robot system were shown to mark the intensity of interest of students to the preparations to the field work research in planetary geology by building robotics and use them in field works. References: [1] Hargitai, H. (2004): 35th LPSC, #1078. LPI, Houston; [2] Bérczi, Sz.; Fabriczy, A.; Hargitai, H.; Hegyi, S.; Illés, E.; Kabai, S.; Kovács, Zs.; Kereszturi, A.; Opitz, A.; Sik, A.; 34th LPSC, #1305. LPI, Houston; [3] Bérczi Sz. Hargitai H., Kereszturi Á., Sik A. (2001, 2005): [4] Roskó, F.; Diósy, T.; Bérczi, Sz.; Fabriczy, A.; Cech, V.; Hegyi, S. (2000): 31st LPSC, #1572. LPI, Houston; [5] Bérczi Sz., Hegyi S., Kovács Zs., Fabriczy A., Földi T., Keresztesi M., Cech V., Drommer B., Gránicz K., Hevesi L., Borbola T., Tóth Sz., Németh I., Horváth Cs., Diósy T., Kovács B., Bordás F., Köllõ Z., Roskó F., Balogh Zs., Koris A., Imrek Gy. (2001, 2002): [6] Bérczi, Sz.; Diósy, T.; Tóth, Sz.; Hegyi, S.; Imrek, Gy.; Kovács, Zs.; Cech, V.; Müller-Bodó, E.; Roskó, F.; Szentpétery, L.; Hudoba, Gy. (2002): 33rd LPSC, #1496. LPI, Houston; [7] Hudoba, Gy.; Kovács, Zs. I.; Pintér, A.; Földi, T.; Hegyi, S.; Tóth, Sz.; Roskó, F.; Bérczi, Sz. (2004): 35th LPSC, #1572. LPI, Houston; [8] Gimesi, L.; Béres, Cs. Z.; Bérczi, Sz.; Hegyi, S.; Cech, V. (2004): 35th LPSC, #1140; [9] Hegyi, S.; Drommer, B.; Hegyi, A.; Biró, T.; Kókány, A.; Hudoba, Gy.; Bérczi, Sz. (2006): 37th LPSC, #1136. LPI, Houston; [10] Bérczi, Sz.; Gál-Sólymos, K.; Gucsik, A.; Hargitai, H.; Józsa, S.; Szakmány, Gy.; Kubovics, I.; Puskás, Z. (2006): 37th LPSC