Science.gov

Sample records for directive priority substances

  1. Monitoring priority substances of directives 76/464/EEC and 2000/60/EC in Greek water bodies.

    PubMed

    Lekkas, Themistokles; Kostopoulou, Maria; Petsas, Andreas; Vagi, Maria; Golfinopoulos, Spyros; Stasinakis, Athanasios; Thomaidis, Nikolaos; Pavlogeorgatos, Gerasimos; Kotrikla, Anna; Gatidou, Georgia; Xylourgidis, Nikolaos; Kolokythas, George; Makri, Christina; Babos, Damianos; Lekkas, Demetris F; Nikolaou, Anastasia

    2003-08-01

    The priority substances of List I, 76/464/EEC Directive, some of which belong to the new Water Framework Directive 2000/60/EC, have been monitored in the surface waters of Greece through the developed network of 53 sampling stations. The analytical methods used for the determination of these substances included Purge and Trap-Gas chromatography-Mass spectrometry for volatile and semivolatile organic compounds, Gas Chromatography-Electron Capture Detection for organochlorine insecticides, High Performance Liquid Chromatography for pentachlorophenol and Atomic Absorption Spectrometry for metals. The results have shown the presence of several priority substances in Greek surface waters, in most cases at concentrations well below the regulatory limits. However, non-compliance was observed for a limited number of compounds. The monitoring network and the analytical determinations have to be expanded to more water bodies and more priority substances, in order to safeguard the quality of Greek surface waters. PMID:12948234

  2. Recent Trends in Monitoring of European Water Framework Directive Priority Substances Using Micro-Sensors: A 2007–2009 Review

    PubMed Central

    Namour, Philippe; Lepot, Mathieu; Jaffrezic-Renault, Nicole

    2010-01-01

    This review discusses from a critical perspective the development of new sensors for the measurement of priority pollutants targeted in the E.U. Water Framework Directive. Significant advances are reported in the paper and their advantages and limitations are also discussed. Future perspectives in this area are also pointed out in the conclusions. This review covers publications appeared since December 2006 (the publication date of the Swift report). Among priority substances, sensors for monitoring the four WFD metals represent 81% of published papers. None of analyzed publications present a micro-sensor totally validated in laboratory, ready for tests under real conditions in the field. The researches are mainly focused on the sensing part of the micro-sensors. Nevertheless, the main factor limiting micro-sensor applications in the environment is the ruggedness of the receptor towards environmental conditions. This point constitutes the first technological obstacle to be overcome for any long-term field tests. PMID:22163635

  3. The hazardous priority substances in Italy: National rules and environmental quality standard in marine environment

    SciTech Connect

    Maggi, Chiara Onorati, Fulvio Lamberti, Claudia Virno Cicero, Anna Maria

    2008-01-15

    Article number 16 of the Water Framework Directive (Directive 2000/60/EC) lays down the community strategy for establishment of harmonised quality standards for the priority substances and other substances posing a significant risk to the aquatic environment. In order to achieve the protection objectives of the Directive 2000/60/EC, the Italian Ministry of the Environment proposed the quality standards for surface water, sediments and biota related to the priority substances listed in the decision No. 2455/2001/EC of the European Parliament and of the Council of November 20 (2001) [Decision N. 2455/2001/EC of the European Parliament and of the Council of 20 November 2001. The list of priority substances in the field of water policy and amending Directive 2000/60/EC. Official Journal of the European Communities, 15.12.2001, p. 5]. Particularly, for the protection of the marine environment, the proposed Italian rules state that, from 1 January 2021, the concentrations of the hazardous priority substances in Italian marine and lagoon waters must be near the natural background for natural substances, like metals, and near zero for the anthropogenic one. According to Directive 2000/60/EC, the Italian Ministry of Environment issued in 2003 Decree 367 in which has derived 160 Environmental Quality Standard (EQS) for water and 27 Environmental Quality Objective (EQO) for sediment of marine coastal area, lagoons and coastal ponds. Biota quality standards have still to be fixed. The paper illustrates the criteria applied for the definition of the quality standards and some comments are presented.

  4. Development of computerized scenarios for wildlife exposure to priority substances

    SciTech Connect

    Brownlee, L.J.; McPherson, S.M.; Norton, M.R.; Ward, D.R.; Lloyd, K.M.

    1995-12-31

    A computerized model has been developed to estimate wildlife exposure in the Canadian environment to substances through inhalation and ingestion of food, water and soil. This Windows application was developed in Visual Basic using Microsoft Access databases and designed to make the evaluation process consistent, transparent and efficient. Bird, mammal, amphibian and reptile species were selected on the basis of food guild, body size, habitat and distribution in Canada. Intake rates were estimated using allometric equations or measured intake rates when available. Ingestion rates were estimated from free-living metabolic rates and dietary composition. With the information, the authors will develop the exposure scenarios required for assessments of risk to wildlife from priority substances listed in the Canadian Environmental Protection Act.

  5. Presence of selected priority and personal care substances in an onsite bathroom greywater treatment facility.

    PubMed

    Eriksson, E; Donner, E; Ledin, A

    2010-01-01

    In recent years, concerns about climate change and the inefficient use and ongoing pollution of water resources have increased the political motivation to encourage water recycling. This has led to the widespread introduction of water saving measures and to advances in the decentralised treatment and reuse of wastewater. In particular, the treatment and reuse of greywater has received attention, although important information such as greywater substance loadings is still only rarely available. With the implementation of the European Water Framework Directive the focus on controlling and phasing-out Priority/Priority Hazardous Substances (PS/PHS) is growing, and it is vital to know their sources and flows in order to generate sustainable emission control strategies. The main objective of this study was to quantify the concentrations and loads of PS/PHS and personal care substances in bathroom greywater, and to thereby assess the contribution of household activities to municipal wastewater loads for these substances. Nickel and mercury may be sourced substantially from household activities as it shown in the paper that bathroom greywater contributed a significant proportion of the overall load of these substances at the municipal wastewater treatment plant. Organic matter in the influent greywater was found to be principally associated with large particles (>8 µm), however it was the dissolved and small sized particles that were predominantly removed in the treatment. PMID:21123919

  6. Pathways analysis of 13 priority substances for PSL2 assessment using fugacity modeling

    SciTech Connect

    Cureton, P.M.; Lloyd, K.; Mackay, D.; Southwood, J.

    1995-12-31

    The Canadian Environmental Protection Act (CEPA) requires the Ministers of the Environment and of Health to establish a Priority Substances List (PSL), that identifies substances to be assessed on a priority basis to determine whether they pose a significant risk to the health of Canadians or to the environment. The second Priority Substances List was released in December 1995 and consists of 25 substances which must be assessed. One of the preliminary steps in assessing these substances is an evaluation of the predicted behavior and fate of the substance in the Canadian environment. Pathways analysis using multimedia fugacity models provided information on the likely environmental partitioning and transformation characteristics. Following a critical evaluation of the physical-chemical values required for the model, Level 1, 2 and 3 fugacity modeling was done on the following 13 PSL2 substances: acetaldehyde, acrylonitrile, butylbenzylphthalate (BBP), carbon disulfide, N,N-Dimethylformamide (DMF), and ethylene oxide, formaldehyde, hexachlorobutadiene, 2-methoxy ethanol, 2-ethoxy ethanol, 2-butoxy ethanol, nitrosodimethylamine (NDMA), and phenol. CHEMCAN was also run using emission rates for appropriate region of Canada. The results of the model results will be discussed in light of problem formulation for ecological risk assessment of these priority substances.

  7. Characterization of priority substances in effluents from an integrated steelworks in the United Kingdom.

    PubMed

    Chen, J; Aries, E; Collins, P; Anderson, D R; Hodges, J S

    2015-02-01

    In the Water Framework Directive, a list of priority substances that are deemed to be persistent, toxic, and liable to bioaccumulate have been identified. Within this list, a range of polycyclic aromatic hydrocarbons (PAHs) and certain trace metals are relevant to the steel industry. This study summarizes work carried out by Tata Steel Europe (Rotherham, U.K.) to characterize the emissions of PAHs and trace metals from wastewater streams at one of its main integrated steelworks in the United Kingdom over a 3-year period (2010 to 2012). The emissions inventory revealed that PAH emissions to water were almost entirely attributable to the cokemaking process, with emissions factors ranging from 20 to 55 mg/tonne of coke. Furthermore, analysis of the PAH distribution in coke oven effluents revealed that medium- and high-molecular-weight PAHs were associated with the suspended solids (particle-bound). Regarding trace metals, both ironmaking and steelmaking processes were the most important emission sources. PMID:25790516

  8. CORRESPONDENCE BETWEEN WHOLE EFFLUENT TOXICITY AND THE PRESENCE OF PRIORITY SUBSTANCES IN COMPLEX INDUSTRIAL EFFLUENT

    EPA Science Inventory

    The purpose of this study was to examine broad-scale correlation between presence of priority substances and whole effluent toxicity (WET) across a range of industry types. Using regression analysis, we examined how chemical-based inferred toxicity predicted measured WET of the e...

  9. Water management in cities of the future using emission control strategies for priority hazardous substances.

    PubMed

    Eriksson, E; Revitt, D M; Ledin, A; Lundy, L; Holten Lützhøft, H C; Wickman, T; Mikkelsen, P S

    2011-01-01

    Cities of the future face challenges with respect to the quantity and quality of water resources, and multiple managerial options need to be considered in order to safeguard urban surface water quality. In a recently completed project on 'Source control options for reducing emissions of Priority Pollutants' (ScorePP), seven emission control strategies (ECSs) were developed and tested within a semi-hypothetical case city (SHCC) to evaluate their potential to reduce the emission of selected European priority hazardous substances (PHSs) to surface waters. The ECSs included (1) business-as-usual, (2) full implementation of relevant European (EU) directives, (3) ECS2 in combination with voluntary options for household, municipalities and industry, (4) ECS2 combined with industrial treatment and best available technologies (BAT), (5) ECS2 in combination with stormwater and combined sewer overflow treatment, (6) ECS2 in combination with advanced wastewater treatment, and (7) combinations of ECS3-6. The SHCC approach was chosen to facilitate transparency, to allow compensating for data gaps and to decrease the level of uncertainty in the results. The selected PHSs: cadmium (Cd), hexachlorobenzene (HCB), nonylphenol (NP) and pentabromodiphenyl ether (PBDE) differ in their uses and environmental fate and therefore accumulate in surface waters to differing extents in response to the application of alternative ECS. To achieve the required reduction in PHS levels in urban waters the full implementation of existing EU regulation is prioritised and feasible combinations of managerial and technological options (source control and treatment) can be highly relevant for mitigating releases. PMID:22105136

  10. Microbial processes and organic priority substances in marine coastal sediments (Adriatic Sea, Italy)

    NASA Astrophysics Data System (ADS)

    Zoppini, Annamaria; Ademollo, Nicoletta; Amalfitano, Stefano; Dellisanti, Walter; Lungarini, Silvia; Miserocchi, Stefano; Patrolecco, Luisa; Langone, Leonardo

    2015-04-01

    PERSEUS EU FP7 Project aims to identify the interacting patterns of natural and human-derived pressures to assess their impact on marine ecosystems and, using the objectives and principles of the Marine Strategy Framework Directive (MSFD) as a vehicle, to design an effective and innovative research governance framework based on sound scientific knowledge. In the frame of this Project (subtask 1.3.3 ADREX: Adriatic and Ionian Seas Experiment), monitoring surveys were conducted in the Adriatic Sea (Italy) in order to study the variation of structural and functional characteristics of native bacterial communities and the occurrence of selected classes of organic priority substances in sediments. The study area represents a good natural laboratory sensitive to climate variability and human pressure, owing to the semi-enclosed nature of the Adriatic Sea and to the increasing trend of human activities in the coastal regions. During the cruise ADRI-13 (November 2013) and ADRI-14 (October 2014) we sampled several coastal sites from the mouth of the Po River to the Otranto strait. Surface sediments were collected in all areas, while sediment cores were sampled in selected sites. Microbes associated with marine sediments play an important role in the C-flux being responsible for the transformation of organic detritus (autochthonous and allochthonous) into biomass. The sediment bacterial abundance was determined by epifluorescence microscopy and the rate of bacterial carbon production by measuring the 3H-leucine uptake rates. The community respiration rate was estimated by the measurement of the electron transport system (ETS) activity. The sediment contamination level was determined by measuring the concentration of contaminants included in the list of organic priority substances: PAHs, bisphenol A (BPA), alkylphenols (APs). The extraction/clean-up of PAHs, BPA and APs was performed by ultrasonic bath with the appropriate solvents, followed by analytical determination with

  11. Direct analysis of organic priority pollutants by IMS

    NASA Technical Reports Server (NTRS)

    Giam, C. S.; Reed, G. E.; Holliday, T. L.; Chang, L.; Rhodes, B. J.

    1995-01-01

    Many routine methods for monitoring of trace amounts of atmospheric organic pollutants consist of several steps. Typical steps are: (1) collection of the air sample; (2) trapping of organics from the sample; (3) extraction of the trapped organics; and (4) identification of the organics in the extract by GC (gas chromatography), HPLC (High Performance Liquid Chromatography), or MS (Mass Spectrometry). These methods are often cumbersome and time consuming. A simple and fast method for monitoring atmospheric organics using an IMS (Ion Mobility Spectrometer) is proposed. This method has a short sampling time and does not require extraction of the organics since the sample is placed directly in the IMS. The purpose of this study was to determine the responses in the IMS to organic 'priority pollutants'. Priority pollutants including representative polycyclic aromatic hydrocarbons (PAHs), phthalates, phenols, chlorinated pesticides, and polychlorinated biphenyls (PCB's) were analyzed in both the positive and negative detection mode at ambient atmospheric pressure. Detection mode and amount detected are presented.

  12. 75 FR 27192 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ...The Environmental Protection Agency (EPA) Region 6 is publishing a direct final Notice of Deletion of the Ruston Foundry Superfund Site (Site), located in Alexandria, Rapides Parish, Louisiana, from the National Priorities List (NPL). The NPL, promulgated pursuant to section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980, as amended, is an......

  13. 76 FR 18066 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ...The Environmental Protection Agency (EPA) Region 1 is publishing a direct final Notice of Deletion of the Norwood PCBs Superfund Site (Site), located in Norwood Massachusetts from the National Priorities List (NPL). The NPL, promulgated pursuant to section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980, as amended, is an appendix of the......

  14. 75 FR 26131 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ...The Environmental Protection Agency (EPA) Region II is publishing a direct final Notice of Deletion of the Asbestos Dump Superfund Site (Site), located in Long Hill Township and Harding Township, New Jersey, from the National Priorities List (NPL). The NPL, promulgated pursuant to section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980, as......

  15. 78 FR 49939 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ...The U.S. Environmental Protection Agency Region 5 is publishing a direct final Notice of Deletion of the Quincy Smelter and Calumet Lake parcels of Operable Unit 3 (OU3) of the Torch Lake Superfund Site (Site), located in Houghton County, Michigan, from the National Priorities List (NPL). The NPL, promulgated pursuant to Section 105 of the Comprehensive Environmental Response, Compensation,......

  16. 76 FR 56294 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... of the direct final action (76 FR 41719) is effective as of September 13, 2011. ADDRESSES.... 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p. 193. Dated... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan...

  17. Directions in Substance Abuse Counseling, 2000.

    ERIC Educational Resources Information Center

    Cohen, Adam W., Ed.

    2000-01-01

    This volume of six lessons provides expert information on a variety of issues in substance abuse counseling. The lessons, which may be applied toward continuing education credits, are: (1) "Ethics in Substance Abuse Rehabilitation" (Robert L. Hewes); (2) "Addressing the Needs of Clients with Traumatic Injury and Alcoholism" (Charles H.…

  18. Adoption of medications in substance abuse treatment: priorities and strategies of single state authorities.

    PubMed

    Rieckmann, Traci; Kovas, Anne E; Rutkowski, Beth A

    2010-09-01

    Research has confirmed the effectiveness of medications, when used in conjunction with ongoing counseling, to treat substance abuse disorders. This article describes a national, mixed-methods research project designed to investigate single state authorities' (SSAs) perceptions of adoption of evidence-based practices in substance abuse treatment. Results are focused specifically on medication-assisted treatment, one of five evidence-based practices defined by the National Quality Forum. Medication-assisted treatment (MAT) is an important and effective part of comprehensive care options available to clients who are chronically ill with alcohol and other drug disorders. Despite mounting clinical evidence and increased availability, overall rates of implementation and sustained adoption of medications to treat addiction remain limited. The results illustrate that the SSA representatives who fund public treatment programs believe MAT is a priority and worthy of system-wide implementation. Current strategies utilized by SSAs to support the adoption of MAT are detailed, as are barriers to adoption and implementation. PMID:21138199

  19. National superfund program priorities, fiscal year 1994. Directive

    SciTech Connect

    Not Available

    1994-01-31

    The memorandum provides the FY 1994 National Superfund Program Priorities for Regions and Headquarters. There are nine major Superfund priorities: Accelerated Cleanup and Emergency Response; Enforcement First; Enforcement Fairness; Military Base Closure; NPL Construction Completions; Contracts Management; Environmental Justice and Meaningful Community Involvement; Enhancement of State Role and Development of Deferral Options; and Innovative Technologies.

  20. Toxicity testing of NCSRP priority substances for the development of soil quality criteria

    SciTech Connect

    Cureton, P.M.; Balch, G.; Lintott, D.; Poirrier, K.; Goudey, S.

    1994-12-31

    The effects of 14 National Contaminated Sites Remediation Program (NCSRP) priority substances was measured on emergence and root elongation in lettuce (Lactuca saliva) and radish (Raphanus saliva) and on survival of the earthworm Eisenia foetida. The worm and seedling emergence tests were conducted in an artificial soil mixture composed of 10% peat moss, 20% kaolinite clay, and 70% silica sand (70 mesh) spiked with the contaminant. The root elongation tests were conducted on filter paper moistened with the contaminant solution. The following endpoints were derived on nominal and measured concentrations: NOEC, LOEC, the LC{sub 50} and LC{sub 25} for earthworm mortality and the EC{sub 50} and EC{sub 25} for emergence and root elongation. The contaminants tested included: arsenic, cadmium, chromium, copper, lead, mercury, zinc, vanadium, benzo(a)pyrene, cyanide, naphthalene, ethylene glycol, pentachlorophenol, and phenol. Each test was repeated three times using different batches of freshly prepared soil, seed lots and worm cultures. The authors will present the findings and discuss the application of toxicity test results in developing generic soil quality criteria.

  1. Implementation of E.U. Water Framework Directive: source assessment of metallic substances at catchment levels.

    PubMed

    Chon, Ho-Sik; Ohandja, Dieudonne-Guy; Voulvoulis, Nikolaos

    2010-01-01

    The E.U. Water Framework Directive (WFD) aims to prevent deterioration of water quality and to phase out or reduce the concentrations of priority substances at catchment levels. It requires changes in water management from a local scale to a river basin scale, and establishes Environmental Quality Standards (EQS) as a guideline for the chemical status of receiving waters. According to the Directive, the standard and the scope of the investigation for water management are more stringent and expanded than in the past, and this change also needs to be applied to restoring the level of metals in water bodies. The aim of this study was to identify anthropogenic emission sources of metallic substances at catchment levels. Potential sources providing substantial amounts of such substances in receiving waters included stormwater, industrial effluents, treated effluents, agricultural drainage, sediments, mining drainage and landfill leachates. Metallic substances have more emission sources than other dangerous substances at catchment levels. Therefore, source assessment for these substances is required to be considered more significantly to restore their chemical status in the context of the WFD. To improve source assessment quality, research on the role of societal and environmental parameters and contribution of each source to the chemical distribution in receiving waters need to be carried out. PMID:20081997

  2. Occurrence of emerging contaminants, priority substances (2008/105/CE) and heavy metals in treated wastewater and groundwater at Depurbaix facility (Barcelona, Spain).

    PubMed

    Teijon, Gloria; Candela, Lucila; Tamoh, Karim; Molina-Díaz, Antonio; Fernández-Alba, A R

    2010-08-01

    The presence of 170 pharmaceuticals, personal care products, priority substances according to the 2008/105EU Directive and four metals (Cd, Ni, Hg, Pb) have been investigated at the Llobregat delta, south of Barcelona (Spain). In the area, reclaimed water is destined to satisfy environmental uses, irrigation and the construction of a hydraulic barrier against seawater intrusion in the deep aquifer of the delta. A monitoring survey was undertaken of water samples from a tertiary wastewater treatment plant (Depurbaix), treated waste water with an additional treatment of ultrafiltration, reverse osmosis, and UV disinfection (WWATP, for the hydraulic barrier injection). Groundwater samples from the aquifer receiving recharge were also investigated. The pharmaceutical group of substances was detected in sampled waters at concentrations rarely exceeding a few microg/L, among the compounds Caffeine, Nicotine and Galaxolide (musk fragrance) were found to be present in more than 60% of the samples. Diuron was the only priority substance detected. The four metals were always present in a variable concentration. After the WWATP treatment the majority of analytes are removed from tertiary treated wastewater or their concentration is reduced below 0.1 microg/L. Monitoring revealed a widespread occurrence of analysed compounds in groundwater. Among them Codeine (analgesic), Ibuprofen (anti-inflammatory), Iopamidol, Iopromide (contrast agent) and Paraxanthine (metabolite of caffeine) have only been detected in groundwater, and are not present in water currently being injected in the deep aquifer. PMID:20593552

  3. Monitoring priority substances, other organic contaminants and heavy metals in a volcanic aquifer from different sources and hydrological processes.

    PubMed

    Estevez, Esmeralda; Cabrera, María del Carmen; Fernández-Vera, Juan Ramón; Molina-Díaz, Antonio; Robles-Molina, José; Palacios-Díaz, María del Pino

    2016-05-01

    Irrigation with reclaimed water (R) is necessary to guarantee the sustainability of semi-arid areas. Results obtained during a two years monitoring network (2009-2011) in Gran Canaria are presented, including the analysis of chemical parameters, N and S isotopes, priority substances (2008/105/EC, 2013/39/EU), other organic contaminants and heavy metals in groundwater and R used to irrigate a golf course. The aims of this work are to evaluate the contamination in a volcanic aquifer, relate the presence of organic contaminants and heavy metals with the hydrogeochemistry and identify pollution sources in the area. No priority substance exceeded the EU thresholds for surface water, although seventeen were detected in R. The most frequent compounds were hexachlorobenzene, chlorpyrifos ethyl, fluorene, phenanthrene and pyrene. These compounds were detected at low concentration, except chlorpyrifos. Chlorpyrifos ethyl, terbuthylazine, diuron, terbutryn, procymidone, atrazine and propazine exceeded the European threshold concentration for pesticides in groundwater (100ngL(-1)). Therefore, the priority substances chlorpyrifos ethyl and diuron must be included in monitoring studies. The priority pesticides chlorfenvinphos and diazinon were always detected in R but rarely in groundwater. Besides, the existence of contaminants not related to the current R irrigation has been identified. Absence of environmental problems related to heavy metals can be expected. The relationship among contaminant presence, hydrogeochemistry, including the stable isotopic prints of δ(18)O, δ(15)N and δ(34)S and preferential recharge paths has been described. The coastal well shows high values of EC, nitrate, a variable chemistry, and 50% of organic contaminants detected above 100ngL(-1). The well located in the recharge area presents a stable hydrochemistry, the lowest value of δ(15)N and the lowest contaminants occurrence. The area is an example of a complex volcanic media with several

  4. Semipolar polycyclic aromatic compounds: identification of 15 priority substances and the need for regulatory steps under REACH regulation.

    PubMed

    Schwarz, Markus A; Behnke, Andreas; Brandt, Marc; Eisenträger, Adolf; Hassauer, Martin; Kalberlah, Fritz; Seidel, Albrecht

    2014-07-01

    Semipolar polycyclic aromatic compounds (sPACs) are frequently found in association with homocyclic polycyclic aromatic hydrocarbons (PAHs) in substances of unknown or variable composition, complex reaction products, or biological materials (UVCBs) from coal or crude oil and products derived thereof. However, major information deficiencies exist with regard to their prevalence and their toxicological and ecotoxicological potential, persistency, and bioaccumulation characteristics. Therefore, in this work, the environmental concern and relevance of sPACs was addressed in a general, stepwise approach. First, a large list of sPACs was collected and subsequently refined by assessing their persistence, bioaccumulation, and toxicity (PBT) properties by quantitative structure-activity relationship (QSAR) methods and their relevance by determining their respective frequency of occurrence. In this way, 15 priority sPACs were identified. These 15 priority sPACs were further characterized in detail with respect to their ecotoxicological properties, environmental behavior, carcinogenicity, and genotoxicity attributes. All of these 15 substances were quantified in distillate or product samples. In the next step, some principles for nomination of indicator substances, indicative for the overall content of sPACs, are derived. Data gaps on ecotoxicological endpoints preclude final conclusions, but the respective necessary supplemental tests were identified. Five of the 15 sPACs were tentatively characterized as potential substances of very high concern (SVHC) for the environment. The overall results of this study also clearly show that regulatory risk management of homocyclic PAHs within the European Regulation on Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) does not address the environmental concern created by sPACs within UVCBs from coal or crude oil. The study proves the need for additional regulatory steps under REACH and suggests indicator

  5. 77 FR 64748 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... Listed on the National Priorities List (60 FR 55466) on November 1, 1995. As described in 300.425(e)(3... proposed for inclusion on the National Priorities List (NPL) in October of 1984, Federal Register (49 FR...: Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351;...

  6. Priority substances in sediments of the "Carska Bara" special nature reserve, a natural scientific research area on the UNESCO list.

    PubMed

    Grba, Nenad; Krčmar, Dejan; Isakovski, Marijana Kragulj; Jazić, Jelena Molnar; Maletić, Snežana; Pešić, Vesna; Dalmacija, Božo

    2016-11-01

    Surface sediments were subject to systematic long-term monitoring (2002-2014) in the Republic of Serbia (Province of Vojvodina). Eight heavy metals (Ni, Zn, Cd, Cr, Cu, Pb, As and Hg), mineral oils (total petroleum hydrocarbons), 16 EPA PAHs, selected pesticides and polychlorinated biphenyls (PCB) were monitored. As part of this research, this paper presents a sediment contamination spatial and temporal trend study of diverse pollution sources and the ecological risk status of the alluvial sediments of Carska Bara at three representative sampling sites (S1S3), in order to establish the status of contamination and recommend substances of interest for more widespread future monitoring. Multivariate statistical methods including factor analysis of principal component analysis (PCA/FA), Pearson correlation and several synthetic indicators were used to evaluate the extent and origin of contamination (anthropogenic or natural, geogenic sources) and potential ecological risks. Hg, Cd, As, mineral oils and PAHs (dominated by dibenzo(a,h)anthracene and benzo(a)pyrene, contributing 85.7% of the total) are derived from several anthropogenic sources, whereas Ni, Cu, Cr and Zn are convincingly of geogenic origin, and exhibit dual origins. Cd and Hg significantly raise the levels of potential ecological risk for all sampling locations, demonstrating the effect of long-term bioaccumulation and biomagnification. Pb is isolated from the other parameters, implying unique sources. This research suggests four heavy metals (Zn, Cr, Cu and As) and dibenzo(a,h)anthracene be added to the list of priority pollutants within the context of the application of the European Water Framework Directive (WFD), in accordance with significant national and similar environmental data from countries in the region. PMID:27472051

  7. The increasing global health priority of substance use in young people.

    PubMed

    Degenhardt, Louisa; Stockings, Emily; Patton, George; Hall, Wayne D; Lynskey, Michael

    2016-03-01

    Substance use in young people (aged 10-24 years) might disrupt key periods of transition that occur as the adolescent brain undergoes cognitive and emotional development, and key psychosocial transitions are made. Adolescence is the peak time for initiation of substance use, with tobacco and alcohol usually preceding the use of illicit drugs. Substantial variation is noted between countries in the levels, types, and sequences of substance use in young people, indicating that a young person's use of substances depends on their social context, drug availability, and their personal characteristics. The Global Burden of Disease (GBD) 2013 study suggests that the burden attributable to substance use increases substantially in adolescence and young adulthood. In young men aged 20-24 years, alcohol and illicit substance use are responsible for 14% of total health burden. Alcohol causes most health burden in eastern Europe, and illicit drug burden is higher in the USA, Canada, Australia, New Zealand, and western Europe. Large gaps exist in epidemiological data about the extent of drug use worldwide and much of what we know about the natural history of substance use comes from cohort studies in high-income countries undertaken decades ago, which hinders effective global policy responses. In view of the global epidemiological transitions from diseases of poverty to non-communicable diseases, the burden of disease and health risks among adolescents and young adults is likely to change substantially, in ways that will no doubt see substance use playing an increasingly large part. PMID:26905480

  8. 77 FR 67783 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ..., Reporting and recordkeeping requirements, Superfund, Water pollution control, and Water supply. Dated... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan National..., is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). EPA...

  9. 77 FR 31215 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ..., Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Dated: May 8... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National..., as amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency...

  10. 75 FR 63140 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... the National Priorities List (NPL) on September 9, 2010 (75 FR 54779). The portions proposed for... Federal Register notice for the proposed deletion (75 FR 54779) discusses this rationale in detail. DATES... Denver, Colorado. Groundwater contamination associated with Operable Unit 8 will remain on the NPL....

  11. 78 FR 69302 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... significant risk to public health, welfare, or the environment. Sites on the NPL may be the subject of... Notice of Policy Change: Partial Deletion of Sites Listed on the National Priorities List. 60 FR 55466... investigation has shown that the release poses no significant threat to public health or the environment...

  12. 75 FR 34405 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ... the NPL as part of the Internal Parcel Partial Deletion in 2006 (71 FR 43071). DATES: Comments must be... National Priorities List (60 FR 55466 (Nov. 1, 1995)). As described in 40 CFR 300.425(e)(3), a portion of a... proposed to the NPL, excluding the Basin F surface impoundment, on October 15, 1984, (49 FR 40320). On...

  13. 76 FR 41719 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ... the NPL in September 1983 (48 FR 40674) and was finalized to the NPL on September 21, 1984 (49 FR....O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p. 193... Priorities List: Deletion of the Hipps Road Landfill Superfund Site AGENCY: Environmental Protection...

  14. 78 FR 24134 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ...The Environmental Protection Agency (EPA) Region 4 is issuing a Notice of Intent to Delete the Koppers Co., Inc. (Florence Plant) Superfund Site (Site) located in Florence, South Carolina, from the National Priorities List (NPL) and requests public comments on this proposed action. The NPL, promulgated pursuant to section 105 of the Comprehensive Environmental Response, Compensation, and......

  15. 75 FR 54779 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... of Policy Change: Partial Deletion of Sites Listed on the National Priorities List, 60 FR 55466 (Nov... institutional controls (ICs) are functioning properly. The Site was added to the Superfund NPL in 1983 (48 FR... about 1914 to the mid-1920s generated large quantities of radioactive residues in the Denver...

  16. 78 FR 33276 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... Change: Partial Deletion of Sites Listed on the National Priorities List. 60 FR 55466 (Nov. 1, 1995). As... February 26, 2002 (67 FR 8836). The Site was listed on the NPL on April 30, 2003 (68 FR 23094). The.... 12777, 56 FR 54757,3 CFR, 1991 Comp., p.351; E.O. 12580, 52 FR 2923, 3 CFR, 1987 Comp., p.193....

  17. 75 FR 44920 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ...The Environmental Protection Agency (EPA), Region 2, announces the deletion of the SMS Instruments, Inc. Superfund Site (Site), located in Deer Park, Suffolk County, New York, from the National Priorities List (NPL). The NPL, promulgated pursuant to section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980, as amended, is an appendix of the......

  18. 78 FR 44512 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ...The Environmental Protection Agency (EPA) Region 9 is issuing a Notice of Intent to Delete the Sola Optical U.S.A., Inc. Superfund Site (Site) located in Petaluma, California, from the National Priorities List (NPL) and requests public comments on this proposed action. The NPL, promulgated pursuant to section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act......

  19. 77 FR 21919 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ...The Environmental Protection Agency (EPA) Region 5 is issuing a Notice of Intent to Delete the A & F Material Reclaiming, Inc. Superfund Site (Site) located in Greenup, Illinois from the National Priorities List (NPL) and requests public comments on this proposed action. The NPL, promulgated pursuant to Section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act......

  20. 76 FR 70057 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... Priorities List, 60 FR 55466 (Nov. 1, 1995). As described in section 300.425(e)(3) of the NCP, a portion of a... to be placed on the NPL on December 30, 1982 (47 FR 58476); and was placed on the NPL on September 8, 1983 (48 FR 40658). The Site was separated into two operable units (OUs): The first operable unit...

  1. 75 FR 44932 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ...The Environmental Protection Agency (EPA), Region 2, is issuing a Notice of Intent to Delete the SMS Instruments, Inc. Superfund Site (Site), located in Deer Park, New York, from the National Priorities List (NPL) and requests public comments on this proposed action. The NPL, promulgated pursuant to Section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act......

  2. 75 FR 26166 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ...The Environmental Protection Agency (EPA) Region 2 is issuing a Notice of Intent to Delete the Asbestos Dump Superfund Site (Site) located in Meyersville, New Jersey, from the National Priorities List (NPL) and requests public comments on this proposed action. The NPL, promulgated pursuant to section 105 of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of......

  3. 76 FR 71500 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ... National Priorities List (NPL) on September 30, 2011, (76 FR 60777). The NPL, promulgated pursuant to... proposed deletion (76 FR 60777) discusses this rationale in detail. DATES: Comments concerning the proposed... requirements, Superfund, Water pollution control, Water Supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C....

  4. 76 FR 30027 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... FR 55466 (Nov. 1, 1995). As described in 300.425(e)(3) of the NCP, a portion of a site deleted from... proposed for inclusion on the National Priorities List, December 30, 1982, 47 FR 58476, and listed on September 8, 1983, 48 FR 40,658. The Site is in a highly mineralized area of the Colorado Rocky...

  5. 75 FR 48895 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List: Intent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ...The Environmental Protection Agency (EPA) Region 6 is issuing a Notice of Intent to Delete the Rogers Road Municipal Landfill Superfund Site located near Jacksonville, Pulaski County, Arkansas from the National Priorities List (NPL) and requests public comments on this proposed action. The NPL, promulgated pursuant to Section 105 of the Comprehensive Environmental Response, Compensation, and......

  6. 77 FR 14717 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... Listed on the National Priorities List, 60 FR 55466 (Nov. 1, 1995). As described in 300.425(e)(3) of the... October 26, 1989 (54 FR 43779), placed on the NPL August 30, 1990 (55 FR 35509), and is therefore subject... operable unit were deleted from the NPL December 4, 2006 (71 FR 70318). Four areas not deleted in 2006...

  7. 78 FR 45871 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    .... The Site was proposed for placement on the National Priorities List (NPL) on December 30, 1982 (47 FR 58476 (1982-12-30)), and listed on the NPL on September 8, 1983 (48 FR 40658 (1983-09-08)). Currently...: Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351;...

  8. 76 FR 510 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... Priorities List. 60 FR 55466 (Nov. 1, 1995). As described in Sec. 300.425(e)(3) of the NCP, sites deleted... proposed for inclusion on the EPA NPL October 14, 1992 and made final on December 16, 1994 [59 FR 65212....S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O....

  9. 75 FR 43082 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... Priorities List. 60 FR 55466 (Nov. 1, 1995). As described in 300.425(e)(3) of the NCP, a portion of a site... in the final rule appearing in the 7/22/87 Federal Register (52 FR 27620-27642). The Letterkenny Army... Federal Register (54 FR 10512-10517). The parcels to be deleted from the NPL are all in an area known...

  10. 75 FR 33724 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... National Priorities List. 60 FR 55466 (Nov. 1, 1995). As described in 300.425(e)(3) of the NCP, a portion....S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p. 193. Appendix B-- 0 2. Table 1 of Appendix B to Part 300 is...

  11. 78 FR 11589 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    .... EPA proposed the STP site to the National Priorities List (NPL) on October 15, 1984 (49 FR 40320), and added it to the final list on August 30, 1990 (55 FR 35502). In 1985, Kerr-McGee entered into an....O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923, 3 CFR, 1987 Comp., p....

  12. 78 FR 70231 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ... Notice of Policy Change: Deletion of Sites Listed on the National Priorities List, (51 FR 21054) on June... September 18, 1985 (FR 50 37950) and finalized on June 10, 1986 (FR 51 21054). EPA, IDEM, and the three...: Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351;...

  13. 78 FR 66283 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... requirements, Superfund, Water pollution control, Water supply. Dated: September 23, 2013. A. Stanley Meiburg.... 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  14. 76 FR 76336 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  15. 75 FR 55479 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... documentation. The public comment period for the NOIDp was extended through August 16, 2010 (75 FR 42361). EPA..., Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Dated: September... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  16. 76 FR 51316 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  17. 77 FR 58321 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ..., Water pollution control, Water supply. Dated: August 27, 2012. Gwendolyn Keyes Fleming, Regional...)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  18. 76 FR 45484 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  19. 76 FR 50164 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923, 3 CFR, 1987 Comp., p... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan...

  20. 77 FR 46009 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-02

    ..., Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p. 193. Dated... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  1. 75 FR 53268 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  2. 76 FR 41751 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-15

    ..., Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p. 193. Dated... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  3. 76 FR 70105 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List: Partial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3... AGENCY 40 CFR Part 300 National Oil and Hazardous Substance Pollution Contingency Plan...

  4. 76 FR 18136 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ..., Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p. 193. Dated... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  5. 76 FR 49397 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  6. 78 FR 47267 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  7. 76 FR 77457 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ..., Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923, 3 CFR, 1987 Comp., p. 193. Dated... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  8. 78 FR 60809 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ..., Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923, 3 CFR, 1987 Comp., p. 193. Dated... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  9. 76 FR 81904 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  10. 78 FR 11620 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... requirements, Superfund, Water pollution control, and Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923, 3 CFR, 1987 Comp... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan...

  11. 76 FR 45483 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  12. 77 FR 43567 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  13. 76 FR 45432 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ..., Superfund, Water pollution control, Water supply. Dated: July 22, 2011. Al Armendariz, Regional...(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan;...

  14. 76 FR 56362 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-13

    ... Register. DATES: The proposed rule published on July 15, 2011 (76 FR 41751) is withdrawn as of September 13...-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan...

  15. Priority substances in a SW European coastal lagoon - Ria Formosa, Portugal. Twenty years of temporal evolution of metals and butyltins

    NASA Astrophysics Data System (ADS)

    Moreira da Silva, Manuela; Carvalho, Pedro; Paquete, Rita; Nuno Duarte, Duarte; Chícharo, Luís

    2013-04-01

    In the last years the European Union has decided to specifically include nickel, cadmium, plumb and TBT in its list of priority substances in water. Trace metals pose a significant threat to organisms because above threshold availability, act as enzyme inhibitors resulting in adverse ecological effects to sediment-associated biota (e.g. macrophytes, benthos, demersal fish) and to higher-biota (e.g. pelagic fish and aquatic birds). Since 2003 International Maritime Organization called for a ban of the application of tributyltin-based paints. Wide distribution, high hydrophobicity, and persistence of organotin compounds have raised concern about their bioaccumulation, their potential biomagnification in the food webs, and their adverse effects to human health and environment, particularly most recent reviews focuses on possible endocrine disrupting effects of OT's (Galloway, 2006; Nakanishi, 2007; Takahashi et al., 1999; Veltman et al., 2006). Saltmarshes are highly heterogeneous environments that have been suffered pressures by the increasing urbanization and industrialization in the adjacent areas. Saltmarsh sediments integrate inputs of contaminants, like metals and organotin compounds and may act as long-term sources of contaminants. At the Ria Formosa saltmarsh several activities were responsible for long-term contaminants, some of them considered priority substances. This work aims to provide information about the present levels and temporal evolution in the last decades of metals (Mn, Zn, Cu, Cr, Ni, Pb, Mo, Cd and Ag, in addition to Fe and Al) and butyltins (TBT, DBT and MBT) in saltmarsh sediments at south of Portugal. Metals were analysed by atomic absorption spectrometry-AAS. Butyltins were determined, after derivatization, by solid phase micro extraction combined with gas chromatography with mass spectrometry (MS/MS). Results showed that legislation was an effective instrument for the decreasing of contamination levels, to sustainable values to ecosystem

  16. 75 FR 1115 - Invitation for Public Comment on Strategic Research Direction, Research Priority Areas and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-08

    ... Statement in the Federal Register published on April 11, 2000 (65 FR 19477-78) or you may visit http... Research and Innovative Technology Administration Invitation for Public Comment on Strategic Research Direction, Research Priority Areas and Performance Metrics To Guide Departmental Strategic Plan for...

  17. 78 FR 47205 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... to current and future ecological receptors through direct contact, food chain uptake, and incidental..., 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923; 3 CFR, 1987 Comp., p. 193. Appendix...

  18. The Collision of the Adoption and Safe Families Act and Substance Abuse: Research-Based Education and Training Priorities for Child Welfare Professionals

    ERIC Educational Resources Information Center

    Schroeder, Julie; Lemieux, Catherine; Pogue, Rene

    2008-01-01

    A large body of descriptive literature demonstrates the problem of substance abuse in child welfare. The 1997 Adoption and Safe Families Act (ASFA) established time frames that make children's need for permanency the overriding priority in families involved with the child welfare system. Child welfare workers often lack proper knowledge and skill…

  19. 76 FR 57661 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... withdrawal of the direct final action (76 FR 45428) is effective as of September 16, 2011. ADDRESSES... relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991...

  20. 77 FR 59338 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-27

    ... withdrawal of the direct final action published August 20, 2012 (77 FR 50038) is effective as of September 27... recordkeeping requirements, Superfund, Water pollution control, Water Supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923;...

  1. 76 FR 57662 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991... withdrawal of the direct final action (76 FR 45432) is effective as of September 16, 2011....

  2. 76 FR 42055 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... May 24, 2011, EPA published a Notice of Intent for Partial Deletion (76 FR 30081) and a direct final rule of Partial Deletion (76 FR 30027) for the remaining portions of Operable Unit 9 (OU9), the... recordkeeping requirements, Superfund, Water pollution control, Water Supply. Authority: 33 U.S.C....

  3. 78 FR 57799 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ...: This withdrawal of the direct final action published July 24, 2013 (78 FR 44455), is effective as of... recordkeeping requirements, Superfund, Water pollution control, Water supply. Authority: 33 U.S.C. 1321(c)(2); 42 U.S.C. 9601-9657; E.O. 12777, 56 FR 54757, 3 CFR, 1991 Comp., p. 351; E.O. 12580, 52 FR 2923;...

  4. 78 FR 63099 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... in the Federal Register on August 20, 2012 (77 FR 50038-50044). The closing date for comments on the... on September 27, 2012 (77 FR 59338), withdrawing the direct final deletion for the Site and..., Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Dated:...

  5. Occurrence and fate of relevant substances in wastewater treatment plants regarding Water Framework Directive and future legislations.

    PubMed

    Martin Ruel, S; Choubert, J-M; Budzinski, H; Miège, C; Esperanza, M; Coquery, M

    2012-01-01

    The next challenge of wastewater treatment is to reliably remove micropollutants at the microgram per litre range. During the present work more than 100 substances were analysed through on-site mass balances over 19 municipal wastewater treatment lines. The most relevant substances according to their occurrence in raw wastewater, in treated wastewater and in sludge were identified, and their fate in wastewater treatment processes was assessed. About half of priority substances of WFD were found at concentrations higher than 0.1 μg/L in wastewater. For 26 substances, potential non-compliance with Environmental Quality Standard of Water Framework Directive has been identified in treated wastewater, depending on river flow. Main concerns are for Cd, DEHP, diuron, alkylphenols, and chloroform. Emerging substances of particular concern are by-products, organic chemicals (e.g. triclosan, benzothiazole) and pharmaceuticals (e.g. ketoprofen, diclofenac, sulfamethoxazole, carbamazepine). About 80% of the load of micropollutants was removed by conventional activated sludge plants, but about two-thirds of removed substances were mainly transferred to sludge. PMID:22437014

  6. Testing decisions of the TSCA Interagency Testing Committee for chemicals on the Canadian Environmental Protection Act Domestic Substances List and Priority Substances List: Di-tert-butylphenol, ethyl benzene, brominated flame retardants, phthalate esters, chloroparaffins, chlorinated benzenes, and anilines

    SciTech Connect

    Walker, J.D.

    1996-12-31

    In 1976, under section 4(e) of the Toxic Substances Control Act (TSCA), the US Congress created the TSCA Interagency Testing Committee (ITC) to decide which chemicals should be recommended to the Administrator of the US Environmental Protection Agency for testing. In 1988, under the Canadian Environmental Protection Act (CEPA), the Government of Canada created the Domestic Substances List and Priority Substances List. This paper briefly describes the ITC, the different ITC testing decisions and a few of the ITC`s 11,150 testing decisions for the 21,413 chemicals on the CEPA Domestic Substances List and some of the 24 testing decisions for the 44 chemicals and chemical groups on the CEPA.

  7. Points mean prizes: priority points, preferential status and directed organ donation in Israel.

    PubMed

    Cronin, Antonia J

    2014-01-01

    The introduction of Israel's new Organ Transplantation Act in 2010 has enabled the development of a unique priority point system aimed at motivating individual's to donate their organ. The priority point system rewards those who are willing to donate an organ with preferential status and an increased chance of receiving a donor organ, should they come to be in need of one. Preliminary evidence suggests it has considerable public support among Israelis, who appear willing to redress the challenge posed by those who are willing to accept an organ but not willing to donate. Since the Act's introduction Israel has witnessed record numbers signing donor cards and there has been a significant increase in the actual numbers of transplants.One aspect of the new Israeli system that has hitherto not much been considered is its tendency towards a communitarian model of organ donation and the implications this change in emphasis may have for the existing 'opt-in' model based upon autonomy and consent. Gil Siegel draws our attention to this aspect when he sets out his defence of a proposal he refers to as 'directed organ donation to other registered donors', which encourages community responsibility without affecting the established commitment to consent and individual freedom.This commentary provides a brief overview of the new Act and its priority point system. It also examines Siegel's proposal and considers the implications it may have for equity and justice, personal choice and dispositional authority. It is argued that although the proposal brings with it several inevitable hurdles for policy makers these are not insurmountable. Rather, its extraordinary potential to save life and avoid suffering should prompt urgent action at policy level. If such a scheme was successfully implemented in Israel it would represent a landmark change in organ donation and allocation policy, and set an example from which we all could learn. PMID:24565060

  8. Points mean prizes: priority points, preferential status and directed organ donation in Israel

    PubMed Central

    2014-01-01

    The introduction of Israel’s new Organ Transplantation Act in 2010 has enabled the development of a unique priority point system aimed at motivating individual’s to donate their organ. The priority point system rewards those who are willing to donate an organ with preferential status and an increased chance of receiving a donor organ, should they come to be in need of one. Preliminary evidence suggests it has considerable public support among Israelis, who appear willing to redress the challenge posed by those who are willing to accept an organ but not willing to donate. Since the Act’s introduction Israel has witnessed record numbers signing donor cards and there has been a significant increase in the actual numbers of transplants. One aspect of the new Israeli system that has hitherto not much been considered is its tendency towards a communitarian model of organ donation and the implications this change in emphasis may have for the existing ‘opt-in’ model based upon autonomy and consent. Gil Siegel draws our attention to this aspect when he sets out his defence of a proposal he refers to as ‘directed organ donation to other registered donors’, which encourages community responsibility without affecting the established commitment to consent and individual freedom. This commentary provides a brief overview of the new Act and its priority point system. It also examines Siegel’s proposal and considers the implications it may have for equity and justice, personal choice and dispositional authority. It is argued that although the proposal brings with it several inevitable hurdles for policy makers these are not insurmountable. Rather, its extraordinary potential to save life and avoid suffering should prompt urgent action at policy level. If such a scheme was successfully implemented in Israel it would represent a landmark change in organ donation and allocation policy, and set an example from which we all could learn. PMID:24565060

  9. 76 FR 68193 - Notice of the Revised Priority List of Hazardous Substances That Will Be the Subject of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... significant potential threats to human health (see also 52 FR 12866, April 17, 1987). CERCLA section 104(i)(2... hazardous substances (see also 53 FR 41280, October 20, 1988), and to include at least 25 additional hazardous substances in each of the three successive years following the 1988 revision (see 54 FR...

  10. Substance use in women: Current status and future directions

    PubMed Central

    Lal, Rakesh; Deb, Koushik Sinha; Kedia, Swati

    2015-01-01

    Alcohol and substance use, until recently, were believed to be a predominantly male phenomenon. Only in the last few decades, attention has shifted to female drug use and its repercussions in women. As the numbers of female drug users continue to rise, studies attempt to understand gender-specific etiological factors, phenomenology, course and outcome, and issues related to treatment with the aim to develop more effective treatment programs. Research has primarily focused on alcohol and tobacco in women, and most of the literature is from the Western countries with data from developing countries like India being sparse. This review highlights the issues pertinent to alcohol and substance use in women with a special focus to the situation in India. PMID:26330645

  11. Longitudinal Bi-Directional Relationships between Sleep and Youth Substance Use

    ERIC Educational Resources Information Center

    Pasch, Keryn E.; Latimer, Lara A.; Cance, Jessica Duncan; Moe, Stacey G.; Lytle, Leslie A.

    2012-01-01

    Despite the known deficits in sleep that occur during adolescence and the high prevalence of substance use behaviors among this group, relatively little research has explored how sleep and substance use may be causally related. The purpose of this study was to explore the longitudinal bi-directional relationships between sleep duration, sleep…

  12. Research priorities for economic analyses of prevention: current issues and future directions.

    PubMed

    Crowley, D Max; Hill, Laura Griner; Kuklinski, Margaret R; Jones, Damon E

    2014-12-01

    In response to growing interest in economic analyses of prevention efforts, a diverse group of prevention researchers, economists, and policy analysts convened a scientific panel, on "Research Priorities in Economic Analysis of Prevention" at the 19th annual conference of the Society for Prevention Research. The panel articulated four priorities that, if followed in future research, would make economic analyses of prevention efforts easier to compare and more relevant to policymakers and community stakeholders. These priorities are: (1) increased standardization of evaluation methods, (2) improved economic valuation of common prevention outcomes, (3) expanded efforts to maximize evaluation generalizability and impact as well as (4) enhanced transparency and communicability of economic evaluations. In this paper, we define three types of economic analyses in prevention, provide context and rationale for these four priorities as well as related sub-priorities, and discuss the challenges inherent in meeting them. PMID:23963624

  13. Research Priorities for Economic Analyses of Prevention: Current Issues & Future Directions

    PubMed Central

    Crowley, D. Max; Hill, Laura Griner; Kuklinski, Margaret R.; Jones, Damon E.

    2013-01-01

    In response to growing interest in economic analyses of prevention efforts, a diverse group of prevention researchers, economists, and policy analysts convened a scientific panel, on “Research Priorities in Economic Analysis of Prevention” at the 19th annual conference of the Society for Prevention Research. The panel articulated four priorities that, if followed in future research, would make economic analyses of prevention efforts easier to compare and more relevant to policymakers, and community stakeholders. These priorities are: (1) increased standardization of evaluation methods, (2) improved economic valuation of common prevention outcomes, (3) expanded efforts to maximize evaluation generalizability and impact, as well as (4) enhanced transparency and communicability of economic evaluations. In this paper we define three types of economic analyses in prevention, provide context and rationale for these four priorities as well as related sub-priorities, and discuss the challenges inherent in meeting them. PMID:23963624

  14. Longitudinal bi-directional relationships between sleep and youth substance use.

    PubMed

    Pasch, Keryn E; Latimer, Lara A; Cance, Jessica Duncan; Moe, Stacey G; Lytle, Leslie A

    2012-09-01

    Despite the known deficits in sleep that occur during adolescence and the high prevalence of substance use behaviors among this group, relatively little research has explored how sleep and substance use may be causally related. The purpose of this study was to explore the longitudinal bi-directional relationships between sleep duration, sleep patterns and youth substance use behaviors. Participants included 704 mostly white (86.4 %) youth, 51 % female, with a baseline mean age of 14.7 years. Self-reported substance use behaviors included past month alcohol, cigarette, and marijuana use. Sleep measures included sleep duration on weekends and weekdays, total sleep, weekend oversleep, and weekend sleep delay. Cross-lagged structural equation models, accounting for clustering at the school level, were run to determine the longitudinal association between sleep and substance use adjusting for socio-demographic characteristics, pubertal status, body mass index z-score, and depressive symptoms. Cigarette use and weekend sleep were bi-directionally related as were marijuana use and total sleep. No other bi-directional associations were identified. However, alcohol use predicted shorter weekend oversleep and marijuana use predicted increased weekend sleep and weekend oversleep. Sleep patterns and duration also predicted adolescents' cigarette, alcohol, and marijuana use. Sleep, both patterns and duration, and substance use among youth are intertwined. Future research is needed to explore these bi-directional relationships, as well as other important contextual factors that may moderate these associations. PMID:22752878

  15. Screening of emerging contaminants and priority substances (2008/105/EC) in reclaimed water for irrigation and groundwater in a volcanic aquifer (Gran Canaria, Canary Islands, Spain).

    PubMed

    Estévez, Esmeralda; Cabrera, María del Carmen; Molina-Díaz, Antonio; Robles-Molina, José; Palacios-Díaz, María del Pino

    2012-09-01

    In semiarid regions, reclaimed water can be an important source of emerging pollutants in groundwater. In Gran Canaria Island, reclaimed water irrigation has been practiced for over thirty years and currently represents 8% of water resources. The aim of this study was to monitor contaminants of emerging concern and priority substances (2008/105/EC) in a volcanic aquifer in the NE of Gran Canaria where the Bandama Golf Course has been sprinkled with reclaimed water since 1976. Reclaimed water and groundwater were monitoring quarterly from July 2009 to May 2010. Only 43% of the 183 pollutants analysed were detected: 42 pharmaceuticals, 20 pesticides, 12 polyaromatic hydrocarbons, 2 volatile organic compounds and 2 flame retardants. The most frequent compounds were caffeine, nicotine, chlorpyrifos ethyl, fluorene, phenanthrene and pyrene. Concentrations were always below 50 ng L(-1), although some pharmaceuticals and one pesticide, cholrpyrifos ethyl, were occasionally detected at higher concentrations. This priority substance for surface water exceeded the maximum threshold (0.1 μg L(-1)) for pesticide concentration in groundwater (2006/118/EC). Sorption and degradation processes in soil account for more compounds being detected in reclaimed water than in groundwater, and that some contaminants were always detected in reclaimed water, but never in groundwater (flufenamic acid, propyphenazone, terbutryn and diazinon). Furthermore, erythromycin was always detected in reclaimed water (exceeding occasionally 0.1 μg L(-1)), and was detected only once in groundwater. In contrast, some compounds (phenylephrine, nifuroxazide and miconazole) never detected in reclaimed water, were always detected in groundwater. This fact and the same concentration range detected for the groups, regardless of the water origin, indicated alternative contaminant sources (septic tanks, agricultural practices and sewerage breaks). The widespread detection of high adsorption potential compounds

  16. Using chemical reactivity to provide insights into environmental transformations of priority organic substances: the Fe⁰-mediated reduction of Acid Blue 129.

    PubMed

    Shirin, Salma; Balakrishnan, Vimal K

    2011-12-15

    Sulfonated anthracenedione dyes are medium priority organic compounds targeted for environmental assessment under the Government of Canada's Chemical Management Plan (CMP). Since organic compounds undergo transformations in environmental matrices, understanding these transformations is critical for a proper assessment of their environmental fate. In the current study, we used zero-valent iron (ZVI) to provide insight into reductive transformation processes available to the anthracenedione dye, Acid Blue 129 (AB 129), a dye which is used in the textile industry. At high temperatures, we found that AB 129 was rapidly reduced (within 3 h) after being adsorbed onto the ZVI-surface, whereupon decomposition took place via multiple competitive and consecutive reaction pathways. Reaction products were identified using state-of-the-art accurate mass Liquid Chromatography-Quadrupole Time of Flight-Mass Spectroscopy (LC-QToF-MS). Five transformation products were identified, including a genotoxic (and thus, potentially carcinogenic) end-product, 2,4,6-trimethylaniline. The same products were found at room temperature, demonstrating that the transformation pathways revealed here could plausibly arise from biological and/or environmental reductions of AB 129. Our results demonstrate the importance of identifying reaction product arising from priority substances as part of the environmental risk assessment process. PMID:22050543

  17. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5... Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe...

  18. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe...

  19. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5... Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe...

  20. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe...

  1. Longitudinal Bi-directional Relationships Between Sleep and Youth Substance Use

    PubMed Central

    Latimer, Lara A.; Cance, Jessica Duncan; Moe, Stacey G.; Lytle, Leslie A.

    2012-01-01

    Despite the known deficits in sleep that occur during adolescence and the high prevalence of substance use behaviors among this group, relatively little research has explored how sleep and substance use may be causally related. The purpose of this study was to explore the longitudinal bi-directional relationships between sleep duration, sleep patterns and youth substance use behaviors. Participants included 704 mostly white (86.4 %) youth, 51 % female, with a baseline mean age of 14.7 years. Self-reported substance use behaviors included past month alcohol, cigarette, and marijuana use. Sleep measures included sleep duration on weekends and weekdays, total sleep, weekend oversleep, and weekend sleep delay. Cross-lagged structural equation models, accounting for clustering at the school level, were run to determine the longitudinal association between sleep and substance use adjusting for socio-demographic characteristics, pubertal status, body mass index z-score, and depressive symptoms. Cigarette use and weekend sleep were bi-directionally related as were marijuana use and total sleep. No other bidirectional associations were identified. However, alcohol use predicted shorter weekend oversleep and marijuana use predicted increased weekend sleep and weekend oversleep. Sleep patterns and duration also predicted adolescents’ cigarette, alcohol, and marijuana use. Sleep, both patterns and duration, and substance use among youth are intertwined. Future research is needed to explore these bidirectional relationships, as well as other important contextual factors that may moderate these associations. PMID:22752878

  2. Identifying Research Priorities: Themes and Directions for the TESOL International Research Foundation.

    ERIC Educational Resources Information Center

    Tucker, G. Richard; Lightbown, Patsy M.; Snow, Catherine; Christian, Donna; de Bot, Kees; Lynch, Brian K.; Nunan, David; Duff, Patricia A.; Freeman, Donald; Bailey, Kathleen M.

    2001-01-01

    Highlights research priorities for the Teaching English to Speakers of Other Languages (TESOL) field, including the following: age of beginning instruction, learning to read in a second language, dual-language education for English language learners, language assessment and program evaluation, English as a global language, learning English for…

  3. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 3 2013-04-01 2013-04-01 false Substances added directly to human food affirmed... FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE General Provisions § 184.1 Substances added... and handled as a food ingredient; and that the quantity of the ingredient added to food does...

  4. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 3 2012-04-01 2012-04-01 false Substances added directly to human food affirmed... FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE General Provisions § 184.1 Substances added... and handled as a food ingredient; and that the quantity of the ingredient added to food does...

  5. Emergency care research funding in the global health context: trends, priorities, and future directions.

    PubMed

    Vu, Alexander; Duber, Herbert C; Sasser, Scott M; Hansoti, Bhakti; Lynch, Catherine; Khan, Ayesha; Johnson, Tara; Modi, Payal; Clattenburg, Eben J; Hargarten, Stephen

    2013-12-01

    Over the past few decades there has been a steady growth in funding for global health, yet generally little is known about funding for global health research. As part of the 2013 Academic Emergency Medicine consensus conference, a session was convened to discuss emergency care research funding in the global health context. Overall, the authors found a lack of evidence available to determine funding priorities or quantify current funding for acute care research in global health. This article summarizes the initial preparatory research and reports on the results of the consensus conference focused on identifying challenges and strategies to improve funding for global emergency care research. The consensus conference meeting led to the creation of near- and long-term goals to strengthen global emergency care research funding and the development of important research questions. The research questions represent a consensus view of important outstanding questions that will assist emergency care researchers to better understand the current funding landscape and bring evidence to the debate on funding priorities of global health and emergency care. The four key areas of focus for researchers are: 1) quantifying funding for global health and emergency care research, 2) understanding current research funding priorities, 3) identifying barriers to emergency care research funding, and 4) using existing data to quantify the need for emergency services and acute care research. This research agenda will enable emergency health care scientists to use evidence when advocating for more funding for emergency care research. PMID:24341581

  6. Rectal cancer: future directions and priorities for treatment, research and policy in New Zealand.

    PubMed

    Jackson, Christopher; Ehrenberg, Nieves; Frizelle, Frank; Sarfati, Diana; Balasingam, Adrian; Pearse, Maria; Parry, Susan; Print, Cristin; Findlay, Michael; Bissett, Ian

    2014-06-01

    New Zealand has one of the highest incidences of rectal cancer in the world, and its optimal management requires a multidisciplinary approach. A National Rectal Cancer Summit was convened in August 2013 to discuss management of rectal cancer in the New Zealand context, to highlight controversies and discuss domestic priorities for the future. This paper summarises the priorities for treatment, research and policy for rectal cancer services in New Zealand identified as part of the Summit in August. The following priorities were identified: - Access to high-quality information for service planning, review of outcomes, identification of inequities and gaps in provision, and quality improvement; - Engagement with the entire sector, including private providers; - Focus on equity; - Emerging technologies; - Harmonisation of best practice; - Importance of multidisciplinary team meetings. In conclusion, improvements in outcomes for patients with rectal cancer in New Zealand will require significant engagement between policy makers, providers, researchers, and patients in order to ensure equitable access to high quality treatment, and strategic incorporation of emerging technologies into clinical practice. A robust clinical information framework is required in order to facilitate monitoring of quality improvements and to ensure that equitable care is delivered. PMID:24929694

  7. Bi-directional Effects of Peer Relationships and Adolescent Substance Use: A Longitudinal Study.

    PubMed

    McDonough, Meghan H; Jose, Paul E; Stuart, Jaimee

    2016-08-01

    Understanding the predictors of the onset and maintenance of substance use in adolescence is important because it is a recognized health risk. The present longitudinal study examined whether negative peer influence and peer connectedness predicted changes in adolescent alcohol, cigarette, marijuana, and other illegal drug use, and reciprocally whether substance use predicted changes in peer relationships. Adolescents (N = 1940; 52 % female; 52 % European New Zealanders, 30 % Maori, 12 % Pacific Islander) aged 10-15 years completed measures annually for 3 years. Cross-lagged panel models were used to examine bi-directional effects. Negative peer influence predicted increased use of all substances. In turn, alcohol, cigarette, and marijuana use predicted increased negative peer influence, but this effect was inconsistent over time. Peer connectedness, predicted to diminish the frequency of substance use, was found to be unrelated to it. Breaking the reciprocal cycle between peer coercion and substance use would seem to be useful for reducing substance use. PMID:26391360

  8. Treatments of low-priority and the Patient Mobility Directive 2011, an end to legal uncertainty for the English NHS?

    PubMed

    Sheppard, Maria K

    2013-06-01

    The patient mobility case law of the Court of Justice of the European Union created legal uncertainty for the healthcare systems of EU Member States. The Patient Mobility Directive setting out patients' cross-border rights was adopted to end this uncertainty. With the Directive to be transposed into national law by October 2013 this article discusses whether the Directive achieves this objective for the English NHS. It contrasts the legal position of the NHS patient under case law and under the Directive regarding the need for prior authorisation of cross-border treatment, the level of reimbursement and the ambit of the healthcare benefits basket. It is argued that the risk of legal challenge may persist under the Directive, specifically regarding treatments which are classified by health authorities as low priority, namely treatments which are either not 'generally' available or only available subject to certain clinical criteria or access thresholds. PMID:23984495

  9. Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities, 3rd edition.

    PubMed

    Patel, Vikram; Chisholm, Dan; Parikh, Rachana; Charlson, Fiona J; Degenhardt, Louisa; Dua, Tarun; Ferrari, Alize J; Hyman, Steve; Laxminarayan, Ramanan; Levin, Carol; Lund, Crick; Medina Mora, María Elena; Petersen, Inge; Scott, James; Shidhaye, Rahul; Vijayakumar, Lakshmi; Thornicroft, Graham; Whiteford, Harvey

    2016-04-16

    The burden of mental, neurological, and substance use (MNS) disorders increased by 41% between 1990 and 2010 and now accounts for one in every 10 lost years of health globally. This sobering statistic does not take into account the substantial excess mortality associated with these disorders or the social and economic consequences of MNS disorders on affected persons, their caregivers, and society. A wide variety of effective interventions, including drugs, psychological treatments, and social interventions, can prevent and treat MNS disorders. At the population-level platform of service delivery, best practices include legislative measures to restrict access to means of self-harm or suicide and to reduce the availability of and demand for alcohol. At the community-level platform, best practices include life-skills training in schools to build social and emotional competencies. At the health-care-level platform, we identify three delivery channels. Two of these delivery channels are especially relevant from a public health perspective: self-management (eg, web-based psychological therapy for depression and anxiety disorders) and primary care and community outreach (eg, non-specialist health worker delivering psychological and pharmacological management of selected disorders). The third delivery channel, hospital care, which includes specialist services for MNS disorders and first-level hospitals providing other types of services (such as general medicine, HIV, or paediatric care), play an important part for a smaller proportion of cases with severe, refractory, or emergency presentations and for the integration of mental health care in other health-care channels, respectively. The costs of providing a significantly scaled up package of specified cost-effective interventions for prioritised MNS disorders in low-income and lower-middle-income countries is estimated at US$3-4 per head of population per year. Since a substantial proportion of MNS disorders run a

  10. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 3 2011-04-01 2011-04-01 false Substances added directly to human food affirmed as generally recognized as safe (GRAS). 184.1 Section 184.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY...

  11. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Substances added directly to human food affirmed... RECOGNIZED AS SAFE General Provisions § 184.1 Substances added directly to human food affirmed as generally... ingredient added to food does not exceed the amount reasonably required to accomplish the intended...

  12. Multilevel Modeling of Direct Effects and Interactions of Peers, Parents, School, and Community Influences on Adolescent Substance Use

    ERIC Educational Resources Information Center

    Mayberry, Megan L.; Espelage, Dorothy L.; Koenig, Brian

    2009-01-01

    This study tested a social-ecological model of adolescent substance use. Multilevel modeling was used to investigate how systems, such as parents, peers, schools, and communities, directly influence and interact together to influence adolescent substance use. Participants included 14,548 (50.3% female) middle school students who were 78.6% White,…

  13. Community-directed interventions for priority health problems in Africa: results of a multicountry study

    PubMed Central

    2010-01-01

    Abstract Objective To determine the extent to which the community-directed approach used in onchocerciasis control in Africa could effectively and efficiently provide integrated delivery of other health interventions. Methods A three-year experimental study was undertaken in 35 health districts from 2005 to 2007 in seven research sites in Cameroon, Nigeria and Uganda. Four trial districts and one comparison district were randomly selected in each site. All districts had established ivermectin treatment programmes, and in the trial districts four other established interventions – vitamin A supplementation, use of insecticide-treated nets, home management of malaria and short-course, directly-observed treatment for tuberculosis patients – were progressively incorporated into a community-directed intervention (CDI) process. At the end of each of the three study years, we performed quantitative evaluations of intervention coverage and provider costs, as well as qualitative assessments of the CDI process. Findings With the CDI strategy, significantly higher coverage was achieved than with other delivery approaches for all interventions except for short-course, directly-observed treatment. The coverage of malaria interventions more than doubled. The district-level costs of delivering all five interventions were lower in the CDI districts, but no cost difference was found at the first-line health facility level. Process evaluation showed that: (i) participatory processes were important; (ii) recurrent problems with the supply of intervention materials were a major constraint to implementation; (iii) the communities and community implementers were deeply committed to the CDI process; (iv) community implementers were more motivated by intangible incentives than by external financial incentives. Conclusion The CDI strategy, which builds upon the core principles of primary health care, is an effective and efficient model for integrated delivery of appropriate health

  14. "Directive approach" for chinese clients receiving psychotherapy: is that really a priority?

    PubMed

    Ng, Chi Ting Connie; James, Susan

    2013-01-01

    The academic literature often suggests that Chinese people prefer directive approaches in therapy. However, studies on this topic are often based on therapists' self-reports: clients' perceptions are rarely considered. What does "directive approach" mean? Is it what clients prefer? Using cultural psychology and medical anthropology as a theoretical framework, the ethnography explored the experience of psychotherapy from Chinese clients' perspectives. Specifically, using ethnographic interview, eight informants, two male and six female, ranging in age from 40 to 55, were interviewed twice in-depth about their experiences of seeing Chinese therapists. All informants are Chinese immigrants who reside in a major Canadian city and saw at least one Chinese therapist in a community counseling agency within 1 year prior to the interview. In the first interview, informants created group of cards describing a list of hypothesized cultural knowledge regarding psychotherapy. After initial data analysis, the cards were presented to the informants in the second interviews, in which they confirmed and/or rejected the hypotheses by grouping, reorganizing, and ranking the cards. In the end each informant created a number of mind-maps with the cards, which served as a representation of informants' psychological reality of psychotherapy based on their ordinary language. The maps were then further analyzed for themes among informants. Results suggest that clients appreciate therapists who "give homework," "analyze their problems," "talk about strategies that other clients have found useful," "chat," and "provide resources." Results also highlight informants' understanding of their own responsibility for the therapeutic relationship which has never been documented before and has important clinical implications. PMID:23408043

  15. Parental, peer, school, and neighborhood influences on adolescent substance use: direct and indirect effects and ethnic variations.

    PubMed

    Su, Jinni; Supple, Andrew J

    2014-01-01

    The current study examined how contextual influences are related to adolescent substance use using an ethnically diverse sample of adolescents. A total of 5,992 adolescents (5,185 European American, 330 African American, 160 Hispanic American, 179 Asian American, and 138 Southeast Asian American) from Dane county, Wisconsin, completed surveys at school. Structural equation modeling was conducted to examine direct versus indirect effects of parental, peer, school, and neighborhood influences and differences in associations across ethnicity. Results indicated that contextual influences on adolescent substance use were both direct and indirect; the strength of associations between contextual influences and adolescent substance use varied across ethnic groups. PMID:25176117

  16. 21 CFR 184.1 - Substances added directly to human food affirmed as generally recognized as safe (GRAS).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Substances added directly to human food affirmed as..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) DIRECT FOOD... human food affirmed as generally recognized as safe (GRAS). (a) The direct human food ingredients...

  17. HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance-dependent and substance-independent populations.

    PubMed

    Jacobs, Michelle M; Murray, Jacinta; Byrd, Desiree A; Hurd, Yasmin L; Morgello, Susan

    2013-10-01

    It has been postulated that drugs of abuse act synergistically with HIV, leading to increased neurotoxicity and neurocognitive impairment. The CNS impacts of HIV and drug use converge on the mesocorticolimbic dopamine (DA) system, which contains two main receptor subtypes: dopamine receptors 1 (DRD1) and 2 (DRD2). DRD1 and DRD2 have been linked to substance dependence; whether they predict HIV-associated neurocognitive disorder (HAND) is unclear. Using an advanced-stage HIV+ population, we sought to determine if drug dependence impacts the contribution of DA receptor polymorphisms on neurocognition. We observed that both DRD1 and DRD2 polymorphisms were associated with opiate and cocaine dependence (P < 0.05) in Caucasian subjects, but not African-American individuals. Using linear regression analysis, we examined the polymorphisms for associations with neuropsychological performance in global and cognitive domain T-scores (Motor, Processing Speed, Verbal Fluency, Learning, Memory, Executive Functioning, Working Memory) while controlling for opiate and cocaine dependency. In the Motor domain, we observed an association for two DRD2 polymorphisms (P < 0.05) in Caucasian subjects. The effects differed for substance dependence groups as the direction of the correlations with DRD2 were opposite to what was seen in subjects without these dependencies. In African-American subjects, associations were observed in nearly every domain, and again, the direction of the correlation differed between substance-dependent and substance-independent groups. We conclude that studies to examine genetic risk for HAND must carefully account for substance dependence patterns when assaying dopaminergic systems, as the neurobiological substrates of cognition in HIV populations may vary with tonic alterations secondary to chronic substance exposures. PMID:24078558

  18. New Directions in Medication-Facilitated Behavioral Treatment for Substance Use Disorders.

    PubMed

    Dakwar, Elias; Nunes, Edward V

    2016-07-01

    A promising approach to addressing substance use disorders is to integrate pharmacotherapy with a behavioral treatment with which synergy is possible. In this review, we focus on recent research suggesting that this approach may be effective for cocaine and cannabis use disorders, both of which currently lack efficacious medications. We summarize potential targets of pharmacotherapy of particular relevance to combined medication-behavioral treatment and examine preliminary evidence of clinical efficacy. Common to these promising medications is a hypothesized mechanism of action predicated on reversing drug-related neural adaptations, such as high reactivity to stress or drug cues, that might undermine fruitful engagement with behavioral treatment. We also review emerging medications, such as certain glutamatergic and serotonergic agents, which may be feasibly integrated with existing treatments. We conclude with an outline of future directions for research. PMID:27222138

  19. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 31 2013-07-01 2013-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... Biological Treatment Pollutant Daily maximum shall not exceed Monthly average shall not exceed...

  20. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 31 2012-07-01 2012-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5... Biological Treatment Pollutant Daily maximum shall not exceed Monthly average shall not exceed...

  1. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 30 2014-07-01 2014-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5... Biological Treatment Pollutant Daily maximum shall not exceed Monthly average shall not exceed...

  2. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 31 2012-07-01 2012-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... Biological Treatment Pollutant Daily maximum shall not exceed Monthly average shall not exceed...

  3. 40 CFR Table 5 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 31 2013-07-01 2013-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That Do Not Use End-of-Pipe Biological Treatment 5... Biological Treatment Pollutant Daily maximum shall not exceed Monthly average shall not exceed...

  4. 40 CFR Table 4 to Part 455 - BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 30 2014-07-01 2014-07-01 false BAT and NSPS Effluent Limitations for Priority Pollutants for Direct Discharge Point Sources That use End-of-Pipe Biological Treatment 4 Table 4... Biological Treatment Pollutant Daily maximum shall not exceed Monthly average shall not exceed...

  5. Not Just the Needle: The State of HIV Prevention Science among Substance Users and Future Directions

    PubMed Central

    Shoptaw, Steve; Montgomery, Brooke; Williams, Chyvette T.; El-Bassel, Nabila; Aramrattana, Apinun; Metzger, David S.; Kuo, Irene; Bastos, Francisco I.; Strathdee, Steffanie A.

    2013-01-01

    Successes in preventing HIV transmission among substance using populations have focused primarily among injection drug users, which have produced measurable reductions in HIV incidence and prevalence. By contrast, the majority of substances used worldwide are administered by non-injectable means, and there is a dearth of HIV prevention interventions that target non-injecting substance users. Increased surveillance of trends in substance use, especially cocaine (including crack) and methamphetamine in addition to new and emerging substances (e.g., synthetic cannabinoids, cathinones and other amphetamine analogs) are needed to develop and scale-up effective and robust interventions for populations at risk for HIV-transmission via sexual behaviors related to non-injection substance use. Strategies are needed that address unique challenges to HIV prevention for substance users who are HIV-infected and those who are HIV- uninfected and at high risk. We propose a research agenda that prioritizes: (1) ) combination HIV prevention strategies in substance users; (2) behavioral HIV prevention programs that reduce sexual transmission behaviors in non-treatment seeking individuals; (3) medical and/or behavioral treatments for substance abuse that reduce/eliminate substance-related sexual transmission behaviors; and (4) structural interventions to reduce HIV incidence. PMID:23764632

  6. An Evaluation of an Hypothesized Paradigm: The Relationship between Childhood Abuse and Substance Use Mediated by Biopsychosocial Factors among Priority Populations.

    ERIC Educational Resources Information Center

    Simons, Loretta N.

    This study evaluated an hypothesized model of biopsychosocial factors that mediate the relationship between childhood abuse and substance abuse. A questionnaire packet consisting of self-report measures was administered to 160 drug dependent participants with and without co-occurring psychological disorders in residential, partial, and outpatient…

  7. The Role of Key Informants and Direct Patient Interviews in Epidemiological Studies of Substance Abuse

    PubMed Central

    Cicero, Theodore J.; Ellis, Matthew S.; Paradis, Alethea; Ortbal, Zachary

    2010-01-01

    Purpose The present study was undertaken to assess the degree to which key informants’ perceptions of relative abuse liability of opioids in their communities correspond to actual drug use in their patients. Methods Key Informants (N=49), and their patients (N=738) were asked to complete anonymous, independent paper surveys about perceived or actual abuse of nine targeted opioid drugs: buprenorphine, fentanyl, heroin, hydrocodone, hydromorphone, methadone, morphine, oxycodone and tramadol. Results There was a strong correspondence (R=.98) between KI rankings of relative abuse of opioids in their patient population and the actual rank order calculated from their patient’s selection of a primary euphorigenic opioid. The patient surveys not only validated the KI’s conclusions, but also provided a great deal of important information about the nature of the abuse patterns. Notably, significant co-morbidity was found in the patient population: 55% had a history of psychiatric problems; chronic pain of moderate intensity was common; 67% were nicotine dependent; and 43% were diagnosed alcoholics. Discussion Our results demonstrate that KI’s perceived rank order of drugs of choice correlated almost perfectly with their patients’ choice of a primary drug. These data suggest that key informants, as they have for decades in epidemiological research, provide a reliable, high-level view of substance abuse in their catchment area. As such, KIs provide valid and reliable information on scope and patterns of abuse, but if more detail is required about the characteristics of abuse, such as that required for FDA-mandated Risk Evaluation and Mitigation Strategies (REMS), then direct interviews with the abusers themselves seem more appropriate. PMID:21351313

  8. Rationale for a New Direction in Foster Youth Substance Use Disorder Prevention

    PubMed Central

    Braciszewski, Jordan M.; Moore, Roland S.; Stout, Robert L.

    2015-01-01

    Background Of the 463,000 children residing in United States foster care, 29,000 annually exit the system because they have “aged out,” are thus dropped from supportive services, and become responsible for their own housing, finances, and health needs. Given histories of maltreatment, housing instability, and parental substance use, youth preparing to exit care are at substantial risk of developing substance use disorders. Unfortunately, access to services is often limited, both before and after exit from care. Methods With the goal of developing a relevant substance use intervention for these youth, focus groups were conducted with foster care staff, administrators, and parents to assess the feasibility of potential approaches. Results Participants identified several population-specific barriers to delivering adapted intervention models developed for normative populations. They expressed concerns about foster youth developing, then quickly ending, relationships with interventionists, as well as admitting to substance use, given foster care program sanctions for such behavior. Group members stressed the importance of tailoring interventions, using creative, motivational procedures. Conclusions Foster youth seem to encounter unique barriers to receiving adequate care. In light of these results, a novel, engaging approach to overcoming these barriers is also presented. PMID:26229518

  9. Peer Groups and Substance Use: Examining the Direct and Interactive Effect of Leisure Activity

    ERIC Educational Resources Information Center

    Thorlindsson, Thorolfur; Bernburg, Jon Gunnar

    2006-01-01

    This paper explores the relationships among adolescent leisure activities, peer behavior, and substance use. We suggest that peer group interaction can have a differential effect on adolescent deviant behavior depending on the type of leisure pattern adolescents engage in. We analyze data from a representative national sample of Icelandic…

  10. Partner Enabling of Substance Use Disorders: Critical Review and Future Directions.

    ERIC Educational Resources Information Center

    Rotunda, Rob J.; Doman, Kathy

    2001-01-01

    Substance use disorders affect not only the identified client but significant others as well. This article contrasts the enabling and codependency constructs, reviews empirical studies of enabling, and offers a conceptualization of partner responses to addiction that could enhance future research efforts and clinical applications in this area. (BF)

  11. Toxicity of seven priority hazardous and noxious substances (HNSs) to marine organisms: Current status, knowledge gaps and recommendations for future research.

    PubMed

    Rocha, A Cristina S; Reis-Henriques, Maria Armanda; Galhano, Victor; Ferreira, Marta; Guimarães, Laura

    2016-01-15

    Shipping industry and seaborne trade have rapidly increased over the last fifty years, mainly due to the continuous increasing demand for chemicals and fuels. Consequently, despite current regulations, the occurrence of accidental spills poses an important risk. Hazardous and noxious substances (HNSs) have been raising major concern among environmental managers and scientific community for their heterogeneity, hazardous potential towards aquatic organisms and associated social-economic impacts. A literature review on ecotoxicological hazards to aquatic organisms was conducted for seven HNSs: acrylonitrile, n-butyl acrylate, cyclohexylbenzene, hexane, isononanol, trichloroethylene and xylene. Information on the mechanisms of action of the selected HNS was also reviewed. The main purpose was to identify: i) knowledge gaps in need of being addressed in future research; and ii) a set of possible biomarkers suitable for ecotoxicological assessment and monitoring in both estuarine and marine systems. Main gaps found concern the scarcity of information available on ecotoxicological effects of HNS towards marine species and their poorly understood mode of action in wildlife. Differences were found between the sensitivity of freshwater and seawater organisms, so endpoints produced in the former may not be straightforwardly employed in evaluations for the marine environment. The relationship between sub-individual effects and higher level detrimental alterations (e.g. behavioural, morphological, reproductive effects and mortality) are not fully understood. In this context, a set of biomarkers associated to neurotoxicity, detoxification and anti-oxidant defences is suggested as potential indicators of toxic exposure/effects of HNS in marine organisms. Overall, to support the development of contingency plans and the establishment of environmental safety thresholds, it will be necessary to undertake targeted research on HNS ecotoxicity in the marine environment. Research should

  12. Evaluation of the pollution of the surface waters of Greece from the priority compounds of list II, 76/464/EEC directive, and other toxic compounds.

    PubMed

    Lekkas, Themistokles; Kolokythas, George; Nikolaou, Anastasia; Kostopoulou, Maria; Kotrikla, Anna; Gatidou, Georgia; Thomaidis, Nikolaos S; Golfinopoulos, Spyros; Makri, Christina; Babos, Damianos; Vagi, Maria; Stasinakis, Athanasios; Petsas, Andreas; Lekkas, Demetris F

    2004-10-01

    The pollution of the surface waters of Greece from the priority compounds of 76/464/EEC Directive was evaluated. The occurrence of 92 toxic compounds, 64 of which belong to priority compounds of List II, candidates for List I, of 76/464/EEC Directive, was studied in surface waters and wastewater through the developed network of 62 sampling stations, which covers the whole Greek territory. The analytical determination was performed by Purge and Trap-Gas chromatography-Mass spectrometry for volatile and semivolatile organic compounds (VOCs), Gas Chromatography-Electron Capture Detection for organochlorine insecticides, Gas Chromatography-Nitrogen Phosphorous Detection for organophosphorous insecticides, High Performance Liquid Chromatography-Photodiode Array Detection for herbicides, and Electrothermal Atomic Absorption Spectrophotometry and Inductively Coupled Plasma-Atomic Emission Spectrometry (ICP-AES) for metals and the toluene extractable organotin compounds. The concentrations of VOCs and insecticides detected in the surface waters of Greece were very low, whereas the concentrations of herbicides and metals ranged generally at moderate levels. VOCs were detected almost exclusively in the rivers and very rarely in the lakes, while the frequency of occurrence of insecticides, herbicides and metals was similar for rivers and lakes. Water quality objectives (WQO) and emission limit values (ELV) have been laid down in national legal framework for a number of compounds detected in the samples, in order to safeguard the quality of surface waters from any future deterioration. PMID:15337345

  13. Direct and Mediated Effects of a Social-Emotional and Character Development Program on Adolescent Substance Use

    PubMed Central

    Lewis, Kendra M.; Bavarian, Niloofar; Snyder, Frank J.; Acock, Alan; Day, Joseph; DuBois, David L.; Ji, Peter; Schure, Marc B.; Silverthorn, Naida; Vuchinich, Samuel; Flay, Brian R.

    2013-01-01

    Mitigating and preventing substance use among adolescents requires approaches that address the multitude of factors that influence this behavior. Such approaches must be tested, not only for evidence of empirical effectiveness, but also to determine the mechanisms by which they are successful. The aims of the present study were twofold: 1) To determine the effectiveness of a school-based social-emotional and character development (SECD) program, Positive Action (PA), in reducing substance use (SU) among a sample of U.S. youth living in a low-income, urban environment, and 2) to test one mechanism by which the program achieves its success. We used longitudinal mediation analysis to test the hypotheses that: 1) students attending PA intervention schools engage in significantly less SU than students attending control schools, 2) students attending PA intervention schools show significantly better change in SECD than students attending control schools, and 3) the effect of the PA intervention on SU is mediated by the change in SECD. Analyses revealed program effects on both SECD and SU, a relationship between SECD and SU, and the effects of PA on SU were completely mediated by changes in SECD. Future research directions and implications for school-based social-emotional and character development efforts and substance use prevention are addressed. PMID:24308013

  14. Setting Priorities for NIOSH Research

    ERIC Educational Resources Information Center

    Gallagher, Richard E.

    1975-01-01

    The National Institute for Occupational Safety and Health (NIOSH) is attempting to develop total programs of occupational safety and health protection. It has established research criteria and a priority system for evaluating the order of investigating suspect substances or agents based upon the expected gain of the health benefit. (Author/MW)

  15. Direct activation of GABAA receptors by substances in the organic acid fraction of Japanese sake.

    PubMed

    Izu, Hanae; Shigemori, Kensuke; Eguchi, Masaya; Kawane, Shuhei; Fujii, Shouko; Kitamura, Yuji; Aoshima, Hitoshi; Yamada, Yasue

    2017-01-01

    We investigated the effect of substances present in Japanese sake on the response of ionotropic γ-aminobutyric acid (GABA)A receptors expressed in Xenopus oocytes. Sake was fractionated by ion-exchange chromatography. The fraction containing organic acids (OA fraction) showed agonist activities on the GABAA receptor. OA fractions from sake were analyzed by capillary electrophoresis time-of-flight mass spectrometry (CE-TOFMS). Of the 64 compounds identified, 13 compounds showed GABAA receptor agonist activities. Especially, l-lactic acid showed high agonist activity and its EC50 value was 37μM. Intraperitoneal injections of l-lactic acid, gluconic acid, and pyruvic acid (10, 10, and 5mg/kg BW, respectively), which showed agonistic activity on the GABAA receptor, led to significant anxiolytic effects during an elevated plus-maze test in mice. PMID:27507485

  16. A Review of Existing Treatments for Substance Abuse Among the Elderly and Recommendations for Future Directions

    PubMed Central

    Kuerbis, Alexis; Sacco, Paul

    2013-01-01

    Background With population aging, there is widespread recognition that the healthcare system must be prepared to serve the unique needs of substance using older adults (OA) in the decades ahead. As such, there is an increasingly urgent need to identify efficient and effective substance abuse treatments (SAT) for OA. Despite this need, there remains a surprising dearth of research on treatment for OA. Aims of review This review describes and evaluates studies on SAT applied to and specifically designed for OA over the last 30 years with an emphasis on methodologies used and the knowledge gained. Methods Using three research databases, 25 studies published in the last 30 years which investigated the impact of SAT on OA and met specific selection criteria were reviewed. Results A majority of the studies were methodologically limited in that they were pre-to-post or post-test only studies. Of the randomized controlled trials, many were limited by sample sizes of 15 individuals or less per group, making main effects difficult to detect. Thus, with caution, the literature suggests that among treatment seeking OA, treatment, whether age-specific or mixed-age, generally works yielding rates of abstinence comparable to general populations and younger cohorts. It also appears that with greater treatment exposure (higher dosage), regardless of level of care, OA do better. Finally, based on only two studies, age-specific treatment appears to potentiate treatment effects for OA. Like younger adults, OA appear to have a heterogeneous response to treatments, and preliminary evidence suggests a possibility of treatment matching for OA. Conclusions Expansion of research on SAT for OA is urgently needed for maximum effectiveness and efficiency of the healthcare system serving these individuals. Future research needs to include laboratory and community based randomized controlled trials with high internal validity of previously vetted evidenced-based practices, including Motivational

  17. Rural Development: Research Priorities.

    ERIC Educational Resources Information Center

    Whiting, Larry R., Ed.

    Directed at the problem of providing equitable long term rural development, this collection of papers deals with the criteria on which research and educational priorities should be based, given the vast problems and limited resources in the U.S. today. There are 11 papers in this collection: "National Outlook and Perspective" (a plea for…

  18. Stability-indicating simultaneous determination of paracetamol and three of its related substances using a direct GC/MS method.

    PubMed

    Belal, Tarek; Awad, Tamer; Clark, C Randall

    2009-01-01

    A simple, direct, and selective stability-indicating GC/MS procedure was developed for the simultaneous determination of paracetamol (PR) and three of its related substances: 4-aminophenol (4-AP), acetanilide (AD), and 4'-chloroacetanilide (4-CA). The method involved resolution of the underivatized compounds using a 100% dimethylpolysiloxane (Rtx-1) column, and MS detection was carried out in the electron-impact mode. The four compounds were completely resolved in less than 11 min. The fragmentation pathways for the four compounds were described, and the structures of the major fragment ions peaks were proposed. Quantification of the analytes was based on measuring their peak areas. The reliability and analytical performance of the proposed method including linearity, range, precision, accuracy, and detection and quantification limits were statistically validated. Calibration curves were linear over the ranges 75-500, 25-350, 25-350, and 25-350 microg/mL for PR, 4-AP, AD, and 4-CA, respectively. The proposed method was successfully applied for the determination of PR and its related substances in laboratory-prepared mixtures of different proportions. Also, it was applied for the assay of PR in several commercially available pharmaceutical formulations with recoveries of 98.95-100.76%. PMID:20166578

  19. Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system.

    PubMed

    Ma, Qiang; Bai, Hua; Li, Wentao; Wang, Chao; Li, Xinshi; Cooks, R Graham; Ouyang, Zheng

    2016-03-17

    Significantly simplified work flows were developed for rapid analysis of various types of cosmetic and foodstuff samples by employing a miniature mass spectrometry system and ambient ionization methods. A desktop Mini 12 ion trap mass spectrometer was coupled with paper spray ionization, extraction spray ionization and slug-flow microextraction for direct analysis of Sudan Reds, parabens, antibiotics, steroids, bisphenol and plasticizer from raw samples with complex matrices. Limits of detection as low as 5 μg/kg were obtained for target analytes. On-line derivatization was also implemented for analysis of steroid in cosmetics. The developed methods provide potential analytical possibility for outside-the-lab screening of cosmetics and foodstuff products for the presence of illegal substances. PMID:26920774

  20. Priority pollutants in wastewater and combined sewer overflow.

    PubMed

    Gasperi, Johnny; Garnaud, Stéphane; Rocher, Vincent; Moilleron, Régis

    2008-12-15

    Implementation of the European Water Framework Directive and its affiliated directives requires Member States to improve their understanding of priority pollutants (PPs) in urban areas and obviously within wastewater systems. As a direct consequence, this study is intended to furnish data on both PP occurrence and the significance of concentrations in wastewater during dry and wet periods within combined sewers. Various sampling sites within the Paris combined sewer network were selected; for each sample, a total of 66 determinants, including metals, polycyclic aromatic hydrocarbons (PAHs), pesticides, organotins, volatile organic compounds, chlorobenzenes, phthalates and alkylphenols, were analysed. A broad range of PPs was observed in wastewater during dry as well as wet weather periods. Of the 66 elements investigated, 33 and 40 priority substances could be observed in raw sewage and wet weather effluent, respectively. As expected, a majority of metals were present in all samples, reflecting their ubiquitous nature. For both periods, chlorobenzenes and most of the pesticides always remained below the limit of quantification, while the majority of other organic pollutants assessed were identified within the microg l(-1) range. As highlighted by the larger number of substances detected in wet weather samples and the significance of their concentrations, runoff via atmospheric inputs and/or surface leaching was found to induce a wider range of PPs (n=40) and lead to higher concentrations of certain metals, PAHs, pesticides and other individual compounds. The data generated during this survey, which constitutes one of the first studies conducted in Europe to report concentrations for a variety of priority substances in wastewater within combined sewers, may be used in the future to identify PPs of potential significance for dry and wet weather periods and targeted for further investigation. PMID:18814902

  1. A meta-analysis of direct and mediating effects of community coalitions that implemented science-based substance abuse prevention interventions.

    PubMed

    Collins, David; Johnson, Knowlton; Becker, Betsy Jane

    2007-01-01

    This article reports results of a meta-analysis of the effects of a set of community coalitions that implemented science-based substance use prevention interventions as part of a State Incentive Grant (SIG) in Kentucky. The analysis included assessment of direct effects on prevalence of substance use among adolescents as well as assessment of what "risk" and "protective" factors mediated the coalition effects. In addition, we tested whether multiple science-based prevention interventions enhanced the effects of coalitions on youth substance use. Short-term results (using 8th-grade data) showed no significant decreases in six prevalence of substance use outcomes -- and, in fact, a significant though small increase in prevalence of use of one substance (inhalants). Sustained results (using 10th-grade data), however, showed significant, though small decreases in three of six substance use outcomes -- past month prevalence of cigarette use, alcohol use, and binge drinking. We found evidence that the sustained effects on these three prevalence outcomes were mediated by two posited risk factors: friends' drug use and perceived availability of drugs. Finally, we found that the number of science-based prevention interventions implemented in schools within the coalitions did not moderate the effects of the coalitions on the prevalence of drug use. Study limitations are noted. PMID:17613959

  2. The Direct and Indirect Effects of Parental Bonds, Parental Drug Use, and Self-Control on Adolescent Substance Use

    ERIC Educational Resources Information Center

    Hope,Trina L.; Whiteford, Scott W.

    2005-01-01

    Research indicates that parenting has important effects on adolescent substance use. However, the indirect effect of parenting on adolescent substance use via self-control is less understood. Gottfredson and Hirschi's General Theory of Crime has been extensively tested by researchers in the field of criminology, but the theory rarely has been used…

  3. Your Health Priorities Tool

    MedlinePlus

    ... Care Explore Your Treatment Options: Your Health Priorities Tool Home Why Explore Your Options Start the Conversation ... Home > Your Health Priorities Tool Your Health Priorities Tool If you don’t share details about your ...

  4. Evidence for direct cellular protective effect of PL-10 substances (synthesized parts of body protection compound, BPC) and their specificity to gastric mucosal cells.

    PubMed

    Bódis, B; Karádi, O; Németh, P; Dohoczky, C; Kolega, M; Mózsik, G

    1997-01-01

    The direct gastric mucosal cellular effect of four PL-10 substances (a synthesized part of human body protection compound, BPC containing 14 or 15 amino acids) was studied on freshly isolated rat gastric mucosal cells and on a mouse myeloma cell line (Sp2/0-Ag14) in an ethanol-induced cell injury model. The examined substances were not toxic for the cells. Two of them proved to be significantly protective against the direct cellular damaging effect of ethanol (PL 10.1.15AK-3 in 5 microg/ml dose and PL 10.1.AK14-2 dose-dependently, ED50=50 ng/ml) on gastric mucosal cells. This cytoprotective effect was failured on mouse myeloma cells. Based on these results a part of the in vivo protection induced by BPC seems to be a direct cellular protective effect to gastric mucosal cells. PMID:9353174

  5. 40 CFR 300.317 - National response priorities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY... personnel. (b) Stabilizing the situation to preclude the event from worsening is the next priority....

  6. HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance dependent and independent populations

    PubMed Central

    Jacobs, Michelle M.; Murray, Jacinta; Byrd, Desiree A.; Hurd, Yasmin L.; Morgello, Susan

    2013-01-01

    It has been postulated that drugs of abuse act synergistically with HIV, leading to increased neurotoxicity and neurocognitive impairment. The CNS impacts of HIV and drug use converge on the mesocorticolimbic dopamine (DA) system, which contains two main receptor subtypes: dopamine receptor 1 and 2. (DRD1, DRD2). DRD1 and DRD2 have been linked to substance dependence; whether they predict HIV-associated neurocognitive disorder (HAND) is unclear. Using an advanced-stage HIV+ population, we sought to determine if drug dependence impacts the contribution of DA receptor polymorphisms on neurocognition. We observed that both DRD1 and DRD2 polymorphisms were associated with opiate and cocaine dependence (P<0.05) in Caucasian subjects, but not African-American individuals. Using linear regression analysis, we examined the polymorphisms for associations with neuropsychological performance in global and cognitive domain T-scores (Motor, Processing Speed, Verbal Fluency, Learning, Memory, Executive Functioning, Working Memory) while controlling for opiate and cocaine dependency. In the Motor domain, we observed an association for two DRD2 polymorphisms (P<0.05) in Caucasian subjects. The effects differed for substance dependence groups as the direction of the correlations with DRD2 were opposite to what was seen in subjects without these dependencies. In African-American subjects, associations were observed in nearly every domain and again, the direction of the correlation differed between substance dependent and independent groups. We conclude that studies to examine genetic risk for HAND must carefully account for substance dependence patterns when assaying dopaminergic systems, as the neurobiological substrates of cognition in HIV populations may vary with tonic alterations secondary to chronic substance exposures. PMID:24078558

  7. Evaluating the Direction of Effects in the Relationship between Religious versus Non-Religious Activities, Academic Success, and Substance Use

    ERIC Educational Resources Information Center

    Good, Marie; Willoughby, Teena

    2011-01-01

    This longitudinal study tested the "influence of involvement" and "selection" hypotheses for the association between religious versus non-religious activity involvement and two salient indicators of adolescent psychosocial adjustment (substance use and academic achievement). Participants included 3,993 Canadian adolescents (49.4% girls) who were…

  8. The atomic-scale unit, entity: key to a direct and easily understood definition of the SI base unit for amount of substance

    NASA Astrophysics Data System (ADS)

    Leonard, B. P.

    2007-10-01

    The atomic-scale unit, entity (ent), is defined as the number-specific amount of substance, n/N, the amount of substance of a single entity. This unit is an invariant physical quantity (the reciprocal of the Avogadro constant) that serves as the basis for redefining the SI base unit for amount of substance in a direct and easily understood manner. It is argued here that the kilomole should be the base unit in order to avoid factors of 10-3 or 103 appearing in relationships involving both mass and amount of substance expressed in base units. Since, in a compatible formulation, the amount-specific number of entities, N/n (= NA), is equal to Mu/Da, exactly, where Mu = kg kmol-1 = g mol-1 = Da ent-1, exactly, then NA = (kg/Da) kmol-1 = (g/Da) mol-1 = 1 ent-1, exactly. The kilomole can thus be defined very simply as: kmol = \\cal N^{\\ast}\\,ent , exactly, where \\cal N^{\\ast} , the exact kilomole-to-entity amount ratio, is identical to the kilogram-to-dalton mass ratio: \\cal N^{\\ast} \\equiv kmol/ent\\equiv kg/Da . The Avogadro constant, N_A = \\cal N^{\\ast}\\,kmol^{-1} , does not appear explicitly in the defining equation, its reciprocal having been replaced by one entity. Like the dalton, the entity would be categorized as a unit in use with SI.

  9. Priority arbitration mechanism

    DOEpatents

    Garmire, Derrick L.; Herring, Jay R.; Stunkel, Craig B.

    2007-03-06

    A method is provided for selecting a data source for transmission on one of several logical (virtual) lanes embodied in a single physical connection. Lanes are assigned to either a high priority class or to a low priority class. One of six conditions is employed to determine when re-arbitration of lane priorities is desired. When this occurs a next source for transmission is selected based on a the specification of the maximum number of high priority packets that can be sent after a lower priority transmission has been interrupted. Alternatively, a next source for transmission is selected based on a the specification of the maximum number of high priority packets that can be sent while a lower priority packet is waiting. If initialized correctly, the arbiter keeps all of the packets of a high priority packet contiguous, while allowing lower priority packets to be interrupted by the higher priority packets, but not to the point of starvation of the lower priority packets.

  10. Social Priorities as Data

    NASA Astrophysics Data System (ADS)

    Grubert, E.

    2015-12-01

    Decision makers' responses to local risks and expected changes to a community from circumstances like natural hazards, human developments, and demographic changes can greatly affect social and environmental outcomes in a community. Translating physical data based in disciplines like engineering and geosciences into positive outcomes for communities can be challenging and often results in conflict that appears to pit "science" against "the public." Scientists can be reluctant to offer recommendations for action based on their work, often (and often correctly) noting that their role is not to make value judgments for a community - particularly for a community that is not their own. Conversely, decision makers can be frustrated by the lack of guidance they receive to help translate data into effective and acceptable action. The solution posed by this submission, given the goal of co-production of knowledge by scientists and decision makers to foster better community outcomes, is to involve the community directly by integrating social scientific methods that address decision making and community engagement to the scientist-decision maker interaction. Specifically, the missing dataset in many scientist-decision maker interactions is the nature of community priorities. Using scientifically valid methods to rigorously collect and characterize community priorities to help recommend tradeoffs between different outcomes indicated by the work of physical and natural scientists can bridge the gap between science and action by involving the community in the process. This submission presents early work on US preferences for different types of social and environmental outcomes designed to integrate directly with engineering and physical science frameworks like Life Cycle Assessment and Environmental Impact Statements. Cardinal preference data are based on surveys of US adults using tools like the Analytical Hierarchy Process, budget allocation, and ranking.

  11. 76 FR 57662 - National Priorities List, Final Rule No. 52

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ...The Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (``CERCLA'' or ``the Act''), as amended, requires that the National Oil and Hazardous Substances Pollution Contingency Plan (``NCP'') include a list of national priorities among the known releases or threatened releases of hazardous substances, pollutants, or contaminants throughout the United States. The......

  12. 75 FR 9782 - National Priorities List, Final Rule No. 49

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ...The Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (``CERCLA'' or ``the Act''), as amended, requires that the National Oil and Hazardous Substances Pollution Contingency Plan (``NCP'') include a list of national priorities among the known releases or threatened releases of hazardous substances, pollutants, or contaminants throughout the United States. The......

  13. 78 FR 31417 - National Priorities List, Final Rule No. 56

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ...The Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (``CERCLA'' or ``the Act''), as amended, requires that the National Oil and Hazardous Substances Pollution Contingency Plan (``NCP'') include a list of national priorities among the known releases or threatened releases of hazardous substances, pollutants or contaminants throughout the United States. The National......

  14. A primer on potential impacts, management priorities, and future directions for Elodea spp. in high latitude systems: learning from the Alaskan experience

    USGS Publications Warehouse

    Carey, Michael P.; Sethi, Suresh A; Larsen, Sabrina J; Rich, Cecil F

    2016-01-01

    Invasive species introductions in Arctic and Subarctic ecosystems are growing as climate change manifests and human activity increases in high latitudes. The aquatic plants of the genus Elodea are potential invaders to Arctic and Subarctic ecosystems circumpolar and at least one species is already established in Alaska, USA. To illustrate the problems of preventing, eradicating, containing, and mitigating aquatic, invasive plants in Arctic and Subarctic ecosystems, we review the invasion dynamics of Elodea and provide recommendations for research and management efforts in Alaska. Foremost, we conclude the remoteness of Arctic and Subarctic systems such as Alaska is no longer a protective attribute against invasions, as transportation pathways now reach throughout these regions. Rather, high costs of operating in remote Arctic and Subarctic systems hinders detection of infestations and limits eradication or mitigation, emphasizing management priorities of prevention and containment of aquatic plant invaders in Alaska and other Arctic and Subarctic systems.

  15. Subsurface flow and transport of organic chemicals: an assessment of current modeling capability and priority directions for future research (1987-1995)

    SciTech Connect

    Streile, G.P.; Simmons, C.S.

    1986-09-01

    Theoretical and computer modeling capability for assessing the subsurface movement and fate of organic contaminants in groundwater was examined. Hence, this study is particularly concerned with energy-related, organic compounds that could enter a subsurface environment and move as components of a liquid phase separate from groundwater. The migration of organic chemicals that exist in an aqueous dissolved state is certainly a part of this more general scenario. However, modeling of the transport of chemicals in aqueous solution has already been the subject of several reviews. Hence, this study emphasizes the multiphase scenario. This study was initiated to focus on the important physicochemical processes that control the behavior of organic substances in groundwater systems, to evaluate the theory describing these processes, and to search for and evaluate computer codes that implement models that correctly conceptualize the problem situation. This study is not a code inventory, and no effort was made to identify every available code capable of representing a particular process.

  16. Priority in Process Algebras

    NASA Technical Reports Server (NTRS)

    Cleaveland, Rance; Luettgen, Gerald; Natarajan, V.

    1999-01-01

    This paper surveys the semantic ramifications of extending traditional process algebras with notions of priority that allow for some transitions to be given precedence over others. These enriched formalisms allow one to model system features such as interrupts, prioritized choice, or real-time behavior. Approaches to priority in process algebras can be classified according to whether the induced notion of preemption on transitions is global or local and whether priorities are static or dynamic. Early work in the area concentrated on global pre-emption and static priorities and led to formalisms for modeling interrupts and aspects of real-time, such as maximal progress, in centralized computing environments. More recent research has investigated localized notions of pre-emption in which the distribution of systems is taken into account, as well as dynamic priority approaches, i.e., those where priority values may change as systems evolve. The latter allows one to model behavioral phenomena such as scheduling algorithms and also enables the efficient encoding of real-time semantics. Technically, this paper studies the different models of priorities by presenting extensions of Milner's Calculus of Communicating Systems (CCS) with static and dynamic priority as well as with notions of global and local pre- emption. In each case the operational semantics of CCS is modified appropriately, behavioral theories based on strong and weak bisimulation are given, and related approaches for different process-algebraic settings are discussed.

  17. Characterizing direct emissions of perfluoroalkyl substances from ongoing fluoropolymer production sources: A spatial trend study of Xiaoqing River, China.

    PubMed

    Shi, Yali; Vestergren, Robin; Xu, Lin; Song, Xiaowei; Niu, Xiameng; Zhang, Chunhui; Cai, Yaqi

    2015-11-01

    The spatial trend of perfluoroalkyl substances (PFASs) along Xiaoqing River and its tributaries was studied to characterize isomer profiles and quantify emissions from fluoropolymer (FP) manufacturers in China. Substantially elevated ∑PFAS concentrations downstream of tributary 4 demonstrated that the emissions from this FP manufacturer dominated total riverine discharges. Isomer profiles of perfluorooctanoic acid (PFOA) in water displayed a stepwise increase in percentage branched PFOA downstream of tributary 3 (14.0%) and 4 (22.7%) reflecting the importance of FP sources. Strong positive correlations between PFOA isomers in water downstream of tributary 4 indicated that isomer profiles were conserved from emission sources to the final reservoir. Riverine discharges of PFOA (23-67 t/yr) were in agreement with theoretical emission calculations from FP production (68 t/yr) whereas large discrepancies between the two methodologies were observed for perfluorobutanoic acid and perfluoropentanoic acid. Collectively, this study fills critical knowledge gaps for understanding ongoing global sources of PFASs. PMID:26160670

  18. Selective determination of dimenhydrinate in presence of six of its related substances and potential impurities using a direct GC/MS method

    PubMed Central

    Belal, Tarek S.; Abdel-Hay, Karim M.; Clark, C. Randall

    2015-01-01

    A novel simple, direct and selective gas chromatography–mass spectrometry (GC/MS) procedure was developed for the determination of the antihistamine drug dimenhydrinate (DMH) in presence of six of its related substances and potential impurities, namely, diphenylmethane, diphenylmethanol, benzophenone, orphenadrine, caffeine and 8-chlorocaffeine. The method involved resolution of the underivatized compounds using a trifluoropropylmethyl polysiloxane (Rtx-200) capillary column and the mass spectrometric detection was carried out in the electron-impact (EI) mode. Excellent baseline separation of DMH and the cited related substances was achieved in less than 15 min. Quantification of the parent drug DMH was based on measuring its peak area. The reliability and analytical performance of the proposed method were validated with respect to linearity, range, precision, accuracy, specificity, robustness, detection and quantification limits. Calibration curve of DMH was linear over the range 50–500 μg/mL with determination coefficient (R2) = 0.9982. The proposed method was successfully applied for the assay of DMH in tablets dosage form with recoveries >96.80%. PMID:26843970

  19. Substance p.

    PubMed

    Harrison, S; Geppetti, P

    2001-06-01

    This article provides a brief overview of the history of substance P from its discovery in the 1930s to the present day. The development of substance P receptor agonists and antagonists, and more recently the employment of transgenic mice, provide a framework to explore the functional role of substance P. Chronic inflammation and pain are associated with a number of diseases, and it has been proposed that substance P, released from primary afferent nerve endings play a role in these conditions. Recent developments with substance P antagonists have demonstrated the importance of substance P in several models of disease that span from asthma to chronic bronchitis; from cystitis, inflammatory bowel disease to migraine; emesis, depression, pain and seizures. Advancements in the knowledge of the role of substance P, its agonists and antagonists could provide clinical solutions for a variety of chronic inflammatory conditions. PMID:11378438

  20. Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions

    PubMed Central

    Becker, Sara J.

    2014-01-01

    The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed. PMID:25937710

  1. Aquatic risk assessment of priority and other river basin specific pesticides in surface waters of Mediterranean river basins.

    PubMed

    Silva, Emília; Daam, Michiel A; Cerejeira, Maria José

    2015-09-01

    To meet good chemical and ecological status, Member States are required to monitor priority substances and chemicals identified as substances of concern at European Union and local/river-basin/national level, respectively, in surface water bodies, and to report exceedances of the environmental quality standards (EQSs). Therefore, standards have to be set at national level for river basin specific pollutants. Pesticides used in dominant crops of several agricultural areas within the catchment of Mediterranean river basins ('Mondego', 'Sado' and 'Tejo', Portugal) were selected for monitoring, in addition to the pesticides included in priority lists defined in Europe. From the 29 pesticides and metabolites selected for the study, 20 were detected in surface waters of the river basins, seven of which were priority substances: alachlor, atrazine, chlorfenvinphos, chlorpyrifos, endosulfan, simazine and terbutryn, all of which exceeded their respective EQS values. QSs for other specific pollutants were calculated using different extrapolation techniques (i.e. deterministic or probabilistic) largely based on the method described in view of the Water Framework Directive. Non-acceptable aquatic risks were revealed for molinate, oxadiazon, pendimethalin, propanil, terbuthylazine, and the metabolite desethylatrazine. Implications of these findings for the classification of the ecological status of surface water bodies in Portugal and at the European level are discussed. PMID:26002046

  2. Direction and magnitude of change in soil use for a wetland area in Chile: Puren marshes, a priority site for biodiversity conservation (stage 1).

    NASA Astrophysics Data System (ADS)

    Sepúlveda-Varas, Alejandra

    2014-05-01

    Land managers and policymakers need information about soil change caused by anthropogenic and non-anthropogenic factors to predict the effects of management on soil function, compare alternatives, and make decisions. This is particularly relevant in highly fragile ecosystems such as wetlands or humid systems. The wetlands require the presence of three key components: hydric soils, hydrophytic vegetation and wetland hydrology. Therefore, the presence of hydric soils in humid systems is essential for the existence of a wetland. In Chile, one of the geographic zones with the greatest diversity of humid systems is the coast of the Araucanía Region, which contains one of the largest and most threatened humid systems of the region, Puren Marshes, whose soils are only generically described as alluvial terraces and miscellaneous swamp. In this area, studies have reported a high intensity of anthropogenic activity, generating soil erosion, loss of wetland coverage and landscape alteration. For this first stage of a main investigation about the vulnerability of hydric soils to changes in patterns of soil use, the objective was to characterize the variables of soil use in the Puren Marshes and determinate the direction and magnitude of change in soil use in the study area for the period between 1994 and 2007 (the official reports indicate that until 1994, the total area of Puren Marshes was 1147 ha). For the analyses, were used official reports of soil use, the coverages were obtained from the project map databases "Catastro y Evaluación de los Recursos Vegetacionales Nativos de Chile" 1993 and its update for La Araucanía, Regional Government of La Araucanía 2011, DMF CONAF 2010 and IGM 2007. The map information was processed in ARCGIS 9.3.1 software under UTM coordinates, datum WGS 84 and 18 South Time extended. Was developed a multitemporal analysis by construction of transition matrix and confusion matrix. The results obtained show that for the period analysed, the

  3. Millennial Perspectives and Priorities

    ERIC Educational Resources Information Center

    Therrell, James A.; Dunneback, Staci K.

    2015-01-01

    Through prioritizing student voice, this study investigated the perspectives of millennial students in relation to their preferences and priorities for how they desired to experience teaching and learning. While not experts, our assumption was that undergraduate students, because of their relatively long experience as students, would be closely in…

  4. Sifting Academic Priorities.

    ERIC Educational Resources Information Center

    Dickeson, Robert C.

    1999-01-01

    Cost control in higher education is hampered by the failure of governing boards to focus on the value and quality of academic programs, and barriers to board priority-setting are significant. However, boards must understand the need for reform, identify responsible administrative leadership, reaffirm institutional mission, define what constitutes…

  5. Inclusion Practice Priorities Instrument.

    ERIC Educational Resources Information Center

    Montie, Jo; And Others

    This instrument was developed to assist individuals or teams to review best practice indicators regarding the development of inclusive school communities and to establish priority targets for improvement. The instrument covers three areas: (1) school community issues, (2) team issues, and (3) classroom issues. For each area, there is a review…

  6. Priorities of Test Publishers

    ERIC Educational Resources Information Center

    Hoepfner, Ralph; Doherty, William J.

    1973-01-01

    The profiles of seven major publishers of elementary-level tests were prepared from systematic ratings of the qualities of their tests. Meaningful rating differences among the publishers' priorities were found and three types of publishers could be identified and described. (Authors)

  7. Direct Detection of Fe(II) in Extracellular Polymeric Substances (EPS) at the Mineral-Microbe Interface in Bacterial Pyrite Leaching

    PubMed Central

    Mitsunobu, Satoshi; Zhu, Ming; Takeichi, Yasuo; Ohigashi, Takuji; Suga, Hiroki; Jinno, Muneaki; Makita, Hiroko; Sakata, Masahiro; Ono, Kanta; Mase, Kazuhiko; Takahashi, Yoshio

    2016-01-01

    We herein investigated the mechanisms underlying the contact leaching process in pyrite bioleaching by Acidithiobacillus ferrooxidans using scanning transmission X-ray microscopy (STXM)-based C and Fe near edge X-ray absorption fine structure (NEXAFS) analyses. The C NEXAFS analysis directly showed that attached A. ferrooxidans produces polysaccharide-abundant extracellular polymeric substances (EPS) at the cell-pyrite interface. Furthermore, by combining the C and Fe NEXAFS results, we detected significant amounts of Fe(II), in addition to Fe(III), in the interfacial EPS at the cell-pyrite interface. A probable explanation for the Fe(II) in detected EPS is the leaching of Fe(II) from the pyrite. The detection of Fe(II) also indicates that Fe(III) resulting from pyrite oxidation may effectively function as an oxidizing agent for pyrite at the cell-pyrite interface. Thus, our results imply that a key role of Fe(III) in EPS, in addition to its previously described role in the electrostatic attachment of the cell to pyrite, is enhancing pyrite dissolution. PMID:26947441

  8. Direct Detection of Fe(II) in Extracellular Polymeric Substances (EPS) at the Mineral-Microbe Interface in Bacterial Pyrite Leaching.

    PubMed

    Mitsunobu, Satoshi; Zhu, Ming; Takeichi, Yasuo; Ohigashi, Takuji; Suga, Hiroki; Jinno, Muneaki; Makita, Hiroko; Sakata, Masahiro; Ono, Kanta; Mase, Kazuhiko; Takahashi, Yoshio

    2016-03-26

    We herein investigated the mechanisms underlying the contact leaching process in pyrite bioleaching by Acidithiobacillus ferrooxidans using scanning transmission X-ray microscopy (STXM)-based C and Fe near edge X-ray absorption fine structure (NEXAFS) analyses. The C NEXAFS analysis directly showed that attached A. ferrooxidans produces polysaccharide-abundant extracellular polymeric substances (EPS) at the cell-pyrite interface. Furthermore, by combining the C and Fe NEXAFS results, we detected significant amounts of Fe(II), in addition to Fe(III), in the interfacial EPS at the cell-pyrite interface. A probable explanation for the Fe(II) in detected EPS is the leaching of Fe(II) from the pyrite. The detection of Fe(II) also indicates that Fe(III) resulting from pyrite oxidation may effectively function as an oxidizing agent for pyrite at the cell-pyrite interface. Thus, our results imply that a key role of Fe(III) in EPS, in addition to its previously described role in the electrostatic attachment of the cell to pyrite, is enhancing pyrite dissolution. PMID:26947441

  9. Stability-indicating determination of trimetazidine dihydrochloride inthe presence of two of its related substances using a direct GC/MS method.

    PubMed

    Belal, Tarek S; Awad, Tamer; Clark, C Randall

    2014-01-01

    A novel, simple, direct, and selective stability- indicating GC/MS procedure was developed for the determination of the anti-ischemic drug trimetazidine dihydrochloride (TMZ) in the presence of two of its related substances (potential impurities), namely, 2,3,4-trimethoxybenzyl alcohol (T1) and 2,3,4-trimethoxybenzaldehyde (T2). The method involved resolution of the undeilvatized compounds using a 100% dimethylpolysiloxane (Rtx-1) capillary column, and MS detection was carried out in the electron-impact mode. The peaks of the three compounds eluted at retention times 11.69, 11.92, and 15.47 min for T1, T2, and TMZ, respectively. Quantification of the parent drug TMZ was based on measuring its peak area. The reliability and analytical performance of the proposed method, including linearity, range, precision, accuracy, selectivity, detection, and quantification limits, were statistically validated. The calibration curve of TMZ was linear over the range 100-600 μg/mL. The proposed method was successfully applied to the assay of TMZ in several commercially available pharmaceutical formulations with recoveries not lessthan 96.2%. PMID:25632428

  10. 40 CFR 300.317 - National response priorities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Operational Response Phases for Oil Removal § 300.317 National response priorities. (a) Safety of... securing the source of the spill and/or removing the remaining oil from the container (vessel, tank,...

  11. 40 CFR 300.317 - National response priorities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 28 2014-07-01 2014-07-01 false National response priorities. 300.317 Section 300.317 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Operational Response Phases...

  12. 40 CFR 300.425 - Establishing remedial priorities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Establishing remedial priorities. 300.425 Section 300.425 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND... satisfies all of the following criteria: (i) The Agency for Toxic Substances and Disease Registry has...

  13. Assigning Priorities for Fixed Priority Preemption Threshold Scheduling

    PubMed Central

    2015-01-01

    Preemption threshold scheduling (PTS) enhances real-time schedulability by controlling preemptiveness of tasks. This benefit of PTS highly depends on a proper algorithm that assigns each task feasible scheduling attributes, which are priority and preemption threshold. Due to the existence of an efficient optimal preemption threshold assignment algorithm that works with fully assigned priority orderings, we need an optimal priority assignment algorithm for PTS. This paper analyzes the inefficiency or nonoptimality of the previously proposed optimal priority assignment algorithms for PTS. We develop theorems for exhaustively but safely pruning infeasible priority orderings while assigning priorities to tasks for PTS. Based on the developed theorems, we correct the previously proposed optimal priority assignment algorithm for PTS. We also propose a performance improved optimal priority assignment algorithm for PTS proving its optimality. The empirical evaluation results clearly show the effectiveness of the proposed algorithm. PMID:26688828

  14. Priority management system

    SciTech Connect

    Simpson, W.A.

    1990-12-18

    Westinghouse Idaho Nuclear Company (WINCO) operates the Idaho Chemical Processing Plant (ICPP) for the US Department of Energy at the Idaho National Engineering Laboratory (INEL). This plant recovers Uranium-235 and rare gases from spent nuclear fuel. Improved fuel processing and waste management methods are also developed at this site. Facilities at ICPP include spent fuel storage and reprocessing areas, a waste solidification facility and related waste storage bins, remote analytical laboratories, and a coal-fired steam generation plant. Maintaining and modernizing a plant of this complexity presents difficult, but not unique problems in scheduling and resource management. WINCO accomplishes the many tasks inherent in any maintenance and construction program by using a Priority Management System. This system allows WINCO to provide integrated and systematic review of all aspects of design and construction, thus meeting customer requirements. This paper provides an overview of the priority setting process and necessary actions to fully implement the system.

  15. Priorities for Venus Exploration

    NASA Astrophysics Data System (ADS)

    Glaze, L. S.; Beauchamp, P. M.; Chin, G.; Crisp, D.; Grimm, R. E.; Herrick, R. R.; Johnston, S.; Limaye, S. S.; Smrekar, S. E.; Ocampo, A.; Thompson, T. W.

    2013-12-01

    Venus remains one of the most enigmatic bodies in our Solar System. Important questions remain regarding the origin and evolution of the atmosphere, the history of the surface and interior, and how the surface and atmosphere interact. In a broader context, understanding Venus has implications for understanding the evolution of terrestrial planets in our Solar System as well as for interpreting the growing set of observations of extra-solar planets. The Venus Exploration Analysis Group (VEXAG), established in 2005, is chartered by NASA's Planetary Science Division and reports its findings to the NASA Advisory Council. Open to all interested scientists, VEXAG regularly evaluates Venus exploration goals, scientific objectives, investigations and critical measurement requirements, including especially recommendations in the NRC Decadal Survey and the Solar System Exploration Strategic Roadmap. At the last general meeting in November 2012, VEXAG resolved to update the scientific priorities and strategies for Venus exploration. To achieve this goal, three major tasks were defined for 2013, (1) update the document prioritizing Goals, Objectives and Investigations for Venus Exploration, (2) develop a Roadmap for Venus exploration that is consistent with VEXAG priorities as well as Planetary Decadal Survey priorities, and (3) develop a white paper on technologies for Venus missions. Proposed versions of all three documents were presented at the VEXAG general meeting in November 2013. Here, we present the findings and final versions of all three documents for community comment and feedback. A follow-on Workshop on Venus Exploration Targets is also being planned for the early summer of 2014. The workshop will provide a forum for the Venus science community to discuss approaches for addressing high priority investigations. Participants will be encouraged to present their ideas for specific targets on Venus (interior, surface and atmosphere) as well as to present specific data

  16. Micronutrient bioavailability research priorities.

    PubMed

    Casgrain, Amélie; Collings, Rachel; Harvey, Linda J; Boza, Julio J; Fairweather-Tait, Susan J

    2010-05-01

    A micronutrient bioavailability workshop, which involved international experts and members of the scientific community and the food industry, with interactive breakout sessions based on synectics principles, was organized by the International Life Sciences Institute Europe Addition of Nutrients to Food Task Force and the European Commission Network of Excellence European Micronutrient Recommendations Aligned. After presentations by experts, a series of "challenge statements" was discussed. The aim was to address topical issues, in particular those that linked bioavailability with the derivation of micronutrient requirements and dietary recommendations, to identify gaps in knowledge and to consider research priorities. Several generic research priorities were identified, including improving the quality of dietary surveys/food composition tables, the need for more metabolic studies that use stable isotopes and high-quality longer-term interventions, and the development of multifactorial mathematical models. Among the common recurrent factors identified as important were polymorphisms/genotype, consideration of the whole diet, chemical form of the micronutrient, and the determination of physiologic requirements. The involvement of all participants in the structured discussions ensured a broad overview of current knowledge, state-of-the-art research, and consideration of priorities for future research. PMID:20200267

  17. How to Establish Instructional Priorities.

    ERIC Educational Resources Information Center

    Railsback, C. E.

    Establishing instructional priorities in public schools is a worthwhile and important process. Because time and money are insufficient to increase staffing in schools, setting priorities is a necessary component of successful managing. Steps to be taken in setting instructional priorities are as follows: (1) Adopt a statement of mission describing…

  18. 15 CFR 700.11 - Priority ratings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE PRIORITIES AND ALLOCATIONS SYSTEM Industrial Priorities § 700.11 Priority ratings. (a) Levels...

  19. 18 CFR 281.207 - Priority 2 classification.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Priority 2 classification. 281.207 Section 281.207 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY....207 Priority 2 classification. (a) Direct sale customer. (1) Subject to paragraph (a)(2) of...

  20. 18 CFR 281.207 - Priority 2 classification.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Priority 2 classification. 281.207 Section 281.207 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY....207 Priority 2 classification. (a) Direct sale customer. (1) Subject to paragraph (a)(2) of...

  1. 18 CFR 281.207 - Priority 2 classification.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Priority 2 classification. 281.207 Section 281.207 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY....207 Priority 2 classification. (a) Direct sale customer. (1) Subject to paragraph (a)(2) of...

  2. 18 CFR 281.207 - Priority 2 classification.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Priority 2 classification. 281.207 Section 281.207 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY....207 Priority 2 classification. (a) Direct sale customer. (1) Subject to paragraph (a)(2) of...

  3. 18 CFR 281.207 - Priority 2 classification.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Priority 2 classification. 281.207 Section 281.207 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY....207 Priority 2 classification. (a) Direct sale customer. (1) Subject to paragraph (a)(2) of...

  4. 7 CFR 3560.577 - Tenant priorities for labor housing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Tenant priorities for labor housing. 3560.577 Section 3560.577 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Off-Farm Labor Housing § 3560.577 Tenant priorities for labor housing....

  5. 7 CFR 3560.577 - Tenant priorities for labor housing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Tenant priorities for labor housing. 3560.577 Section 3560.577 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Off-Farm Labor Housing § 3560.577 Tenant priorities for labor housing....

  6. Deontics = Betterness + Priority

    NASA Astrophysics Data System (ADS)

    van Benthem, Johan; Grossi, Davide; Liu, Fenrong

    This paper looks at deontic logic as resulting from both a betterness ordering on states (i.e., a 'deontic preference') and a priority ordering on properties (i.e., a 'law' explicitly representing a standard of behavior). The correspondence between these two orderings offers a rich perspective from which to look at deontic scenarios and puzzles, and in particular at contrary-to-duties. The framework naturally lends itself to describing dynamics involving both orderings, thereby providing a new analysis of norm change as 'betterness change'.

  7. Substance Use and Its Prevention: A Survey of Classroom Practices.

    ERIC Educational Resources Information Center

    Genaux, Melisa; And Others

    1995-01-01

    A nationwide survey of 109 teachers of students with behavioral disorders found little programming concerning prevention of substance abuse. Teachers differed in their priority assignment of substance abuse prevention and reported the absence of parental involvement in such efforts. Lack of time, curriculum materials, and adequate funding were…

  8. 7 CFR 1465.4 - National priorities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... identify national priorities to achieve the conservation objectives of AMA. (b) National priorities will be... priorities in conjunction with State and local priorities to prioritize and select AMA applications...

  9. Priority Queues for Computer Simulations

    NASA Technical Reports Server (NTRS)

    Steinman, Jeffrey S. (Inventor)

    1998-01-01

    The present invention is embodied in new priority queue data structures for event list management of computer simulations, and includes a new priority queue data structure and an improved event horizon applied to priority queue data structures. ne new priority queue data structure is a Qheap and is made out of linked lists for robust, fast, reliable, and stable event list management and uses a temporary unsorted list to store all items until one of the items is needed. Then the list is sorted, next, the highest priority item is removed, and then the rest of the list is inserted in the Qheap. Also, an event horizon is applied to binary tree and splay tree priority queue data structures to form the improved event horizon for event management.

  10. Priorities for Endometriosis Research

    PubMed Central

    Rogers, Peter A. W.; D’Hooghe, Thomas M.; Fazleabas, Asgerally; Gargett, Caroline E.; Giudice, Linda C.; Montgomery, Grant W.; Rombauts, Luk; Salamonsen, Lois A.; Zondervan, Krina T.

    2009-01-01

    Endometriosis is an estrogen-dependent disorder where endometrial tissue forms lesions outside the uterus. Endometriosis affects an estimated 10% of women in the reproductive-age group, rising to 30% to 50% in patients with infertility and/or pain, with significant impact on their physical, mental, and social well-being. There is no known cure, and most current medical treatments are not suitable long term due to their side-effect profiles. Endometriosis has an estimated annual cost in the United States of $18.8 to $22 billion (2002 figures). Although endometriosis was first described more than 100 years ago, current knowledge of its pathogenesis, spontaneous evolution, and the pathophysiology of the related infertility and pelvic pain, remain unclear. A consensus workshop was convened following the 10th World Congress on Endometriosis to establish recommendations for priorities in endometriosis research. One major issue identified as impacting on the capacity to undertake endometriosis research is the need for multidisciplinary expertise. A total of 25 recommendations for research have been developed, grouped under 5 subheadings: (1) diagnosis, (2) classification and prognosis, (3) treatment and outcome, (4) epidemiology, and (5) pathophysiology. Endometriosis research is underfunded relative to other diseases with high health care burdens. This may be due to the practical difficulties of developing competitive research proposals on a complex and poorly understood disease, which affects only women. By producing this consensus international research priorities statement it is the hope of the workshop participants that researchers will be encouraged to develop new interdisciplinary research proposals that will attract increased funding support for work on endometriosis. PMID:19196878

  11. Priority nutrition messages.

    PubMed

    1991-01-01

    The Philippine Food and Nutrition Program deliver priority short, simple, clear, and action filled nutrition messages in different languages and dialects to different audiences. Its 1st priority task is to promote breast feeding. It informs mothers that breast milk is the most nutritious food for infants and that it protects them from infectious diseases. The program also encourages breast feeding as long as possible. If mothers cannot breast feed, they should talk to an infant nutrition expert to help them choose the best formula and learn about proper preparation. A 4-6 month infant needs to begin eating small amounts of semisolid nutritious foods. Moreover these foods must include body building foods, such as meat and eggs, and energy providing foods, such as corn and rice. Mothers must 1st attend to food needs of infants and preschoolers since they are more likely to suffer malnutrition than older children and adults. This is especially important when they suffer from an infection. Specifically, the very young need a variety of foods each day including the vitamin and mineral rich vegetables and fruits. In fact, families should grow their own fruits and vegetables to ensure an adequate supply. Hands must be cleaned with soap and water after defecation and before preparing foods. Mothers should add fats and oils when preparing foods because they provide concentrated energy, fatty acids, and fat soluble vitamins. Pregnant mothers must consume increased amounts of fish, beans, and other body building foods as well as regulating foods (vegetables and fruits). Mothers must also space births. They should weigh children each month to monitor nutritional levels. Moreover they must pay attention to signs indicating inadequate and insufficient food intake e.g., underweight and night blindness. PMID:12284666

  12. Toxic Substances Control Act

    SciTech Connect

    Not Available

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  13. Phylogenetically-Informed Priorities for Amphibian Conservation

    PubMed Central

    Isaac, Nick J. B.; Redding, David W.; Meredith, Helen M.; Safi, Kamran

    2012-01-01

    The amphibian decline and extinction crisis demands urgent action to prevent further large numbers of species extinctions. Lists of priority species for conservation, based on a combination of species’ threat status and unique contribution to phylogenetic diversity, are one tool for the direction and catalyzation of conservation action. We describe the construction of a near-complete species-level phylogeny of 5713 amphibian species, which we use to create a list of evolutionarily distinct and globally endangered species (EDGE list) for the entire class Amphibia. We present sensitivity analyses to test the robustness of our priority list to uncertainty in species’ phylogenetic position and threat status. We find that both sources of uncertainty have only minor impacts on our ‘top 100‘ list of priority species, indicating the robustness of the approach. By contrast, our analyses suggest that a large number of Data Deficient species are likely to be high priorities for conservation action from the perspective of their contribution to the evolutionary history. PMID:22952807

  14. Priorities for Federal Education Statistics.

    ERIC Educational Resources Information Center

    Murnane, Richard J.

    The paper suggests priorities for the federal government's elementary and secondary education data collection efforts. Sections on outputs, inputs, and private schools describe what data is needed, what is already available, and what is recommended for data collection. Recommendations include a high priority for federal funding for the National…

  15. Priorities Statements of Community Colleges.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    In response to recommendations in the Illinois Board of Higher Education's Priorities, Quality, and Productivity report of November 1994, the 52 community colleges in the state prepared priority statements detailing specific college objectives for the current fiscal year (FY). This report provides the second update of the colleges' statements,…

  16. Dreissenid mussel research priorities workshop

    USGS Publications Warehouse

    Sytsma, Mark; Phillips, Stephen; Counihan, Timothy D.

    2016-01-01

    On November 4-5, 2015, a Dreissenid Mussel Research Priorities Workshop funded by the Great Northern Landscape Conservation Cooperative occurred at Portland State University. The purpose of the workshop was to update research priorities in the 2010 Quagga-Zebra Mussel Action Plan in light of the westward expansion of mussels in the United States and Canada.

  17. Microextraction of priority pollutants

    SciTech Connect

    Leepipatriboon, S.

    1984-01-01

    Some of the priority pollutants, e.g., aromatic hydrocarbons, halogenated aromatic hydrocarbons and halogenated alkanes and alkenes have been studied by a microextraction technique. The compounds studied were benzene, toluene, and ethylbenzene for aromatic hydrocarbons; chlorobenzene, m-dichlorobenzene, p-dichlorobenzene, and o-dichlorobenzene for halogenated aromatic hydrocarbons; and trans-1,2-dichloroethylene, 1,1-dichloroethane, 1,1,2,2-tetrachloroethane, choloroform, ethylene chloride, 1,1,1-trichloroethane, carbon tetrachloride, methylene chloride, bromodichloromethane, 1,2-dichloropropane, trichloroethylene and bromoform for halogenated alkanes and alkenes. The organic solvent-to-water sample ratios of study were 1:9, 5:5 and 8:2, respectively. Solvent extractability effect of carbon disulfide, methylene chloride and hexane or iso-octane and the effect of salts, e.g., saturated sodium chloride solution, saturated sodium sulfate solution, 2.00 g of sodium chloride and 2.00 g of sodium sulfate on the percent recovery were investigated in this study. This technique is based on the extraction into an organic solvent phase followed by the measurement of the peak area by a flame ionization detector. Gas chromatography and the internal standard technique were used throughout the stud. The gas chromatographic conditions for each system of study were reported. The standard deviation of this study ranged from 1-16%. The distribution constant, K{sub D}, and the results of percent recovery for each compound are discussed.

  18. Take Action on 5 Policies America Must Adopt To Reduce and Prevent Substance Abuse.

    ERIC Educational Resources Information Center

    Join Together, Boston, MA.

    The Join Together National Policy Panel presents five policies that can help communities reduce and prevent substance abuse. They are: (1) compel substance abuse treatment for criminal offenders; (2) ensure that every person who has an addiction gets treatment; (3) make substance abuse prevention an urgent priority in every community; (4) increase…

  19. Proximal Priority Laser Therapy: PPLT

    NASA Astrophysics Data System (ADS)

    Ohshiro, Toshio

    2004-09-01

    The author has, in the past, classified treatment methods for pain geometrically as point, line, two-dimensional, three-dimensional treatment and has used these over the years. However as a practitioner of western medicine, the author originally treated pain only directed at the painful site, and encountered cases where local treatment did not suffice. The author proved with SPECT and the Rand Phantom that treating the neck which is the midpoint of the brain, the center of the nervous system and the heart, the center of circulation, increased cerebral blood flow and also that laser emitted to neck will reach the spinal chord no matter from where on the neck the laser is emitted. From such research and 25 years of clinical experience, the author has created an anatomy based, systemic treatment method called the Proximal Priority Laser Therapy (PPLT) where not only the cerebral cortex, spinal chord and peripheral nerves are treated but also the tracts of blood vessels and lymph ducts are treated as well. Treatment method and cases are presented herein.

  20. Evolving Perspectives on Monopolization and Priority Effects.

    PubMed

    De Meester, Luc; Vanoverbeke, Joost; Kilsdonk, Laurens J; Urban, Mark C

    2016-02-01

    Biologists are often confronted with high levels of unexplained variation when studying the processes that determine genetic and species diversity. Here, we argue that eco-evolutionary interactions might often play an important role during colonization and have longstanding effects on populations and communities. Adaptation following colonization can produce a strong positive feedback loop that promotes priority effects and context-dependent trajectories of population or species assembly. We establish how monopolization, and more generally evolution-mediated priority effects, influence ecological patterns at multiple scales of space, time, and biological organization. We then highlight the underappreciated implications for our understanding of population and landscape genetics, adaptive evolution, community diversity, biogeography, and conservation biology. We indicate multiple future directions for research, including extending theory beyond competition. PMID:26778169

  1. Congestion pricing by priority auction

    NASA Astrophysics Data System (ADS)

    Zhang, Guanxiang; He, Jianhua; Ma, Yajie; Cheng, Wenqing; Yang, Zongkai

    2005-02-01

    This paper analyzes a communication network facing users with a continuous distribution of delay cost per unit time. Priority queueing is often used as a way to provide differential services for users with different delay sensitivities. Delay is a key dimension of network service quality, so priority is a valuable resource which is limited and should to be optimally allocated. We investigate the allocation of priority in queues via a simple bidding mechanism. In our mechanism, arriving users can decide not to enter the network at all or submit an announced delay sensitive value. User entering the network obtains priority over all users who make lower bids, and is charged by a payment function which is designed following an exclusion compensation principle. The payment function is proved to be incentive compatible, so the equilibrium bidding behavior leads to the implementation of "cμ-rule". Social warfare or revenue maximizing by appropriately setting the reserve payment is also analyzed.

  2. Assessment of fluxes of priority pollutants in stormwater discharges in two urban catchments in Lyon, France

    NASA Astrophysics Data System (ADS)

    Becouze, C.; Bertrand-Krajewski, J. L.; Coquery, M.; Dembélé, A.; Cren-Olivé, C.

    2009-04-01

    Keywords: WFD, priority pollutants, stormwater, sewer systems, atmospheric deposition The European Water Framework Directive (WFD, 2000) requires both a progressive reduction of priority substances discharges and a cessation of hazardous priority substances discharges into water bodies. In order to define priorities for action in a global and integrated urban water management approach, we need to identify and quantify all sources of pollutants (diffuse agricultural and urban emissions, industrial emissions, effluents from wastewater treatment plants, from separate and combined sewer systems, etc.). The objectives of the ESPRIT collaborative project are to identify, evaluate, characterise and later on model the fluxes of priority substances in urban stormwater, for both combined and separate sewer systems. This paper presents i) the methodology applied to collect representative samples of dry atmospheric deposits, of rainwater and of stormwater discharges at the outlet of experimental catchments, ii) the EMC (Event Mean Concentrations) values and the fluxes of 36 organic substances and of 26 metals calculated for various storm events, and iii) the discussion of these results. Two experimental sites have been selected in Lyon for the project: Ecully (combined sewer system draining a 245 ha residential catchment) and Chassieu (separate stormwater system draining a 185 ha industrial catchment). Each catchment outlet is equipped with sensors measuring various parameters (flow depth and velocity, pH, conductivity, turbidity, temperature) and with refrigerated automatic samplers. Each site is also equipped with prototype devices collecting separately samples of both dry atmospheric deposits and rainwater. All sampling devices comply with requirements for trace micro-pollutants monitoring (Teflon tubing, clean glass bottles, etc.). Field and laboratory blank procedures were carried out to quantify the possible contamination along the sampling/conditioning chain. Event mean

  3. CELLULAR TOXICITY IN CHINESE HAMSTER OVARY CELL CULTURES. 1. ANALYSIS OF CYTOTOXICITY ENDPOINTS FOR TWENTY-NINE PRIORITY POLLUTANTS

    EPA Science Inventory

    Chinese hamster ovary cells were exposed to 29 toxic chemical substances which were representative of several classes of compounds listed by the Natural Resources Defense Council Consent Decree as priority toxic pollutants. After cell cultures were exposed to the test substance, ...

  4. Global health prioritiespriorities of the wealthy?

    PubMed Central

    Ollila, Eeva

    2005-01-01

    Health has gained importance on the global agenda. It has become recognized in forums where it was once not addressed. In this article three issues are considered: global health policy actors, global health priorities and the means of addressing the identified health priorities. I argue that the arenas for global health policy-making have shifted from the public spheres towards arenas that include the transnational for-profit sector. Global health policy has become increasingly fragmented and verticalized. Infectious diseases have gained ground as global health priorities, while non-communicable diseases and the broader issues of health systems development have been neglected. Approaches to tackling the health problems are increasingly influenced by trade and industrial interests with the emphasis on technological solutions. PMID:15847685

  5. Setting priorities for safeguards upgrades

    SciTech Connect

    Al-Ayat, R.A.; Judd, B.R.; Patenaude, C.J.; Sicherman, A.

    1987-07-10

    This paper describes an analytic approach and a computer program for setting priorities among safeguards upgrades. The approach provides safeguards decision makers with a systematic method for allocating their limited upgrade resources. The priorities are set based on the upgrades cost and their contribution to safeguards effectiveness. Safeguards effectiveness is measured by the probability of defeat for a spectrum of potential insider and outsider adversaries. The computer program, MI$ER, can be used alone or as a companion to ET and SAVI, programs designed to evaluate safeguards effectiveness against insider and outsider threats, respectively. Setting the priority requires judgments about the relative importance (threat likelihoods and consequences) of insider and outsider threats. Although these judgments are inherently subjective, MI$ER can analyze the sensitivity of the upgrade priorities to these weights and determine whether or not they are critical to the priority ranking. MI$ER produces tabular and graphical results for comparing benefits and identifying the most cost-effective upgrades for a given expenditure. This framework provides decision makers with an explicit and consistent analysis to support their upgrades decisions and to allocate the safeguards resources in a cost-effective manner.

  6. Setting priorities for safeguards upgrades

    SciTech Connect

    Al-Ayat, R.A.; Judd, B.R.; Patenaude, C.J.; Sicherman, A.

    1987-07-01

    This paper describes an analytic approach and a computer program for setting priorities among safeguards upgrades. The approach provides safeguards decision makers with a systematic method for allocating their limited upgrade resources. The priorities are set based on the upgrades cost and their contribution to safeguards effectiveness. Safeguards effectiveness is measured by the probability of defeat for a spectrum of potential insider and outsider adversaries. The computer program, MI$ER, can be used alone or as a companion to ET and SAVI, programs designed to evaluate safeguards effectiveness against insider and outsider threats, respectively. Setting the priority required judgments about the relative importance (threat likelihoods and consequences) of insider and outsider threats. Although these judgments are inherently subjective, MI$ER can analyze the sensitivity of the upgrade priorities to these weights and determine whether or not they are critical to the priority ranking. MI$ER produces tabular and graphical results for comparing benefits and identifying the most cost-effective upgrades for a given expenditure. This framework provides decision makers with an explicit and consistent analysis to support their upgrades decisions and to allocate the safeguards resources in a cost-effective manner.

  7. Global Climate Change Adaptation Priorities for Biodiversity and Food Security

    PubMed Central

    Hannah, Lee; Ikegami, Makihiko; Hole, David G.; Seo, Changwan; Butchart, Stuart H. M.; Peterson, A. Townsend; Roehrdanz, Patrick R.

    2013-01-01

    International policy is placing increasing emphasis on adaptation to climate change, including the allocation of new funds to assist adaptation efforts. Climate change adaptation funding may be most effective where it meets integrated goals, but global geographic priorities based on multiple development and ecological criteria are not well characterized. Here we show that human and natural adaptation needs related to maintaining agricultural productivity and ecosystem integrity intersect in ten major areas globally, providing a coherent set of international priorities for adaptation funding. An additional seven regional areas are identified as worthy of additional study. The priority areas are locations where changes in crop suitability affecting impoverished farmers intersect with changes in ranges of restricted-range species. Agreement among multiple climate models and emissions scenarios suggests that these priorities are robust. Adaptation funding directed to these areas could simultaneously address multiple international policy goals, including poverty reduction, protecting agricultural production and safeguarding ecosystem services. PMID:23991125

  8. [Environment and health: priorities for preventive medicine].

    PubMed

    Rakhmanin, Yu A; Mikhaylova, R I

    2014-01-01

    Contemporary environmental factors influencing the formation of the environment and public health have been analyzed The increasing chemical pollution of the environment (air water, soil, living environment), and the intensification of the impact of physical factors in the first place, "electromagnetic smog" associated with the widespread use of appliances and computer equipment, cellular threaten public health have been shown. In this connection, there were determined priorities and main directions of research in the platform "Preventive Environment", approved by Ministry of Health of Russia, which is based on the concept of the factor prevention of noninfectious diseases. PMID:25831920

  9. Breast augmentation with an unknown substance

    PubMed Central

    Ebrahim, Lamya; Morrison, David; Kop, Alan; Taylor, Donna

    2014-01-01

    Before the widespread use of silicone implants various foreign substances were injected directly into the breasts. The nature of these materials sometimes remains unknown and can cause various complications requiring surgical intervention. Preoperative diagnostic imaging can help characterise the type and distribution of the injected material, thereby assisting in making decisions regarding treatment. We report a case of breast augmentation with an unknown substance, aiming to highlight some imaging characteristics of different breast augmentation substances. PMID:24957586

  10. The substance view: a critique.

    PubMed

    Lovering, Rob

    2013-06-01

    According to the theory of intrinsic value and moral standing called the 'substance view,' what makes it prima facie seriously wrong to kill adult human beings, human infants, and even human fetuses is the possession of the essential property of the basic capacity for rational moral agency - a capacity for rational moral agency in root form and thereby not remotely exercisable. In this critique, I cover three distinct reductio charges directed at the substance view's conclusion that human fetuses have the same intrinsic value and moral standing as adult human beings. After giving consideration to defenders of the substance view's replies to these charges, I then critique each of them, ultimately concluding that none is successful. Of course, in order to understand all of these things - the reductio charges, defenders of the substance view's replies to them, and my criticisms of their replies - one must have a better understanding of the substance view (in particular, its understanding of rational moral agency) as well as its defense. Accordingly, I address the substance view's understanding of rational moral agency as well as present its defense. PMID:22296684

  11. Cairo conference affirms CEDPA priorities.

    PubMed

    1995-01-01

    The International Conference on Population and Development (ICPD) that was held in Cairo during September adopted a 20-year Programme of Action endorsing the empowerment of women as the foundation of sustainable development. 178 countries and more than a 1000 nongovernmental organizations (NGOs), including the Centre for Development and Population Activities (CEDPA), from 100 countries attended the conference and the parallel NGO forum. The final document sets out specific steps for achievement of universal access to a full range of voluntary, quality family planning and reproductive health services for women and men; provision of services for the special needs of adolescents; closure of the gender gap in education; and empowerment of women via education, health care, and economic options. The CEDPA network of alumnae from 30 countries had worked over the 3 years prior to the conference for the inclusion of women's priorities in policies and to achieve consensus among the government and NGO caucuses. 14 alumnae, including Peggy Curlin (CEDPA President and US delegate), were appointed to their countries' delegations and directly influenced the Programme of Action. The NGO Forum provided a place to exchange experiences and expertise; CEDPA mounted an exhibit, "Empowering Women." The network's theme was "Access, Choice, and Participation." With support from the United Nations Population Fund, CEDPA developed a manual, "After Cairo: A Handbook on Advocacy for Women Leaders," which has been distributed at training sessions and workshops and was translated into French (with support from the US Agency for International Development in Mali) for distribution at the Dakar conference in November in preparation for the World Conference on Women. CEDPA and The Global Committee for Cairo honored the secretary-general of the conference, Dr. Nafis Sadik, for her leadership of the ICPD and UNFPA, and Aziza Hussein, co-chair of the NGO steering committee, at a luncheon; Dr. Sadik

  12. Science Indicators and Science Priorities.

    ERIC Educational Resources Information Center

    Brooks, Harvey

    1982-01-01

    Discusses science/society interface and difficulties involved in developing realistic science indicators. Topics include: intrinsic vs. extrinsic indicators; four problems society faces as a result of technological activities (toxic chemicals, radioactive wastes, auto safety, cancer); research and development (R&D) priorities; international…

  13. Systemwide Communications Plan and Priorities.

    ERIC Educational Resources Information Center

    Reed, Ann

    The Board of Governors of the California Community Colleges has repeatedly identified the strengthening of communications as a key component to developing the California Community Colleges (CCC) as a system. The genesis of communications planning, activities and priorities took place in 1989 with the Burson-Marsteller Communications Action Plan,…

  14. National Priorities for Vocational Education.

    ERIC Educational Resources Information Center

    Ruff, Richard D.; And Others

    National priorities exist that can be served through federal legislation for the funding of vocational education. Four alternatives that are examples of national needs that vocational education would appear to have a potential to address are (1) training and retraining of workers in national critical skill shortage occupations, (2) training and…

  15. Report on Tribal Priority Allocations.

    ERIC Educational Resources Information Center

    Bureau of Indian Affairs (Dept. of Interior), Washington, DC.

    As part of Bureau of Indian Affairs (BIA) funding, Tribal Priority Allocations (TPA) are the principal source of funds for tribal governments and agency offices at the reservation level. According to their unique needs and circumstances, tribes may prioritize funding among eight general categories: government, human services, education, public…

  16. Priorities Statements of Community Colleges.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    Each year since 1994, the 52 community colleges in Illinois prepare priority statements detailing specific college objectives for the current fiscal year (FY). This report provides the third update of the colleges' statements, covering FY 1998. Brief statements, from one to four pages, are provided for the following colleges: Belleville Area…

  17. National Institutional Priorities Report, 1997.

    ERIC Educational Resources Information Center

    USA Group Noel-Levitz, Iowa City, IA.

    This document reports on a study that gathered information about how colleges and universities view their effectiveness in meeting the expectations of their students. By quantifying the importance that faculty, staff, and administrators place on student expectations, the institution is able to pinpoint its strengths and to assign priorities for…

  18. National Institutional Priorities Report, 2003.

    ERIC Educational Resources Information Center

    USA Group Noel-Levitz, Iowa City, IA.

    This report describes the seventh annual National Institutional Priorities Study conducted to determine the perceptions of faculty, administration, and staff regarding areas of highest importance and areas of greatest and least agreement on meeting student expectations. Also identified were the greatest performance gaps between levels of…

  19. National Institutional Priorities Report, 2002.

    ERIC Educational Resources Information Center

    USA Group Noel-Levitz, Iowa City, IA.

    This report describes the sixth annual National Institutional Priorities Study conducted to determine the perceptions of faculty, administration, and staff regarding areas of highest important and areas of greatest and least agreement on meeting student expectations. Also identified were the greatest performance gaps between levels of importance…

  20. Enrollees Choose Priorities for Medicare

    ERIC Educational Resources Information Center

    Danis, Marion; Biddle, Andrea K.; Goold, Susan Dorr

    2004-01-01

    Purpose: The purpose of this study was to demonstrate the feasibility and results of ascertaining Medicare enrollees' priorities for insured medical benefits. Design and Methods: Structured group exercises were conducted with Medicare enrollees from clinical and community settings in central North Carolina. By participating in a decision exercise,…

  1. National Priorities List book set

    SciTech Connect

    Not Available

    1991-01-01

    The report provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) sites. The set of documents compiles State-Specific site summary fact sheets on each site being cleaned up under the Superfund program. The individual state sites are available as PB91-921207, and PB91-921209 thru PB91-921258.

  2. Direct laser writing of μ-chips based on hybrid C-Au-Ag nanoparticles for express analysis of hazardous and biological substances.

    PubMed

    Bashouti, M Y; Manshina, A; Povolotckaia, A; Povolotskiy, A; Kireev, A; Petrov, Y; Mačković, M; Spiecker, E; Koshevoy, I; Tunik, S; Christiansen, S

    2015-04-01

    Micro-chips based on organic-inorganic hybrid nanoparticles (NPs) composed of nanoalloys of gold (Au) and silver (Ag) embedded in an amorphous carbonaceous matrix (C-Au-Ag NPs) were prepared directly on a substrate by the laser-induced deposition (for short: LID) method. The C-Au-Ag NPs show a unique plasmon resonance which enhances Raman scattering of analytes, making the μ-chips suitable to detect ultra-low-volumes (10(-12) liter) and concentrations (10(-9) M) of bio-agents and a hazardous compound. These micro-chips constitute a novel, flexible solid-state device that can be used for applications in point-of-care diagnostics, consumer electronics, homeland security and environmental monitoring. PMID:25673275

  3. CONTROL OF ORGANIC SUBSTANCES IN WATER AND WASTEWATER

    EPA Science Inventory

    The presence of organic substances of industrial origin in wastewaters, storm runoff and in surface and groundwaters may not always be an unmitigated evil--but, it is safe to say, it never is good. In 1976, EPA was required to give special emphasis to 129 'priority pollutants' th...

  4. Perinatal Substance Abuse: What's Best for the Children?

    ERIC Educational Resources Information Center

    Poulsen, Marie Kanne

    This report, which is based on the work of the Perinatal Substance Exposure Think Tanks, establishes priorities for statewide services in California to young children who are prenatally exposed to alcohol and drugs. Although the report focuses on the developmental needs of children, it also examines efforts to provide prevention and treatment…

  5. Photovoltaic-cell-research priorities

    SciTech Connect

    Bornstein, J.G.; Hien, L.K.; Silberglitt, R.

    1983-09-30

    The current state of research and development on photovoltaic materials and advanced concepts are reviewed, and priority research activities for improved photovoltaic cells in the major individual research areas (i.e., silicon, III-V materials, II-VI materials) are identified. Also noted is the importance of reserving a small but finite portion of photovoltaic research funding for out-of-the-mainstream research. The major features of a research management philosophy aimed at attracting the best available scientific resources and research capabilities to photovoltaic research and development are outlined. The priority research activities in the principal areas of photovoltaic research are then summarized and compared, and the overall conclusions of the assessment are presented. (LEW)

  6. National Priorities List sites: Texas

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  7. National Priorities List sites: Minnesota

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  8. National Priorities List sites: Oklahoma

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  9. National Priorities List sites: Colorado

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  10. National Priorities List sites: Nebraska

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  11. National Priorities List sites: Delaware

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  12. National Priorities List sites: Washington

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  13. National Priorities List sites: Florida

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  14. National Priorities List sites: Alabama

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  15. National Priorities List sites: Massachusetts

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  16. National Priorities List sites: Mississippi

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  17. National Priorities List sites: Hawaii

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  18. National Priorities List sites: Maine

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  19. National Priorities List sites: Ohio

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  20. National Priorities List sites: Connecticut

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  1. National Priorities List sites: Utah

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  2. National Priorities List sites: Oregon

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  3. National Priorities List sites: Virginia

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  4. National Priorities List sites: Iowa

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  5. National Priorities List sites: Arkansas

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  6. National Priorities List sites: Vermont

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  7. National Priorities List sites: Idaho

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  8. National Priorities List sites: Georgia

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  9. National Priorities List sites: Missouri

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.

  10. National Priorities List sites: Louisiana

    SciTech Connect

    Not Available

    1990-09-01

    Together with the companion National Overview volume this publication provides general Superfund background information and descriptions of activities at each State National Priorities List (NPL) site. The document is intended to clearly describe what the problems are, what EPA and others participating in site cleanups are doing, and how the Nation can move ahead in solving these serious problems. The State volume compiles site summary fact sheets on each State site being cleaned up under the Superfund program.