Sample records for dong quai angelica

  1. Gynaecomastia and the herbal tonic "Dong Quai".

    PubMed

    Goh, S Y; Loh, K C

    2001-03-01

    We present a case of a man who developed gynaecomastia after ingestion of "Dong Quai" pills. "Dong Quai" is the Chinese name for the herb Angelica polymorpha var. sinensis which is widely used as a panacea for gynaecological problems, and it is also proclaimed as an invigorating tonic for both women and men. The pharmacological effects of "Dong Quai" are likely related to the phytoestrogen that it contains. This report highlights the potential adverse effects associated with its consumption in the male, especially for the processed "Dong Quai" pills which may contain significantly higher levels of phytoestrogen than its original herbal product. PMID:11405562

  2. Dong Quai (angelica sinensis) in the treatment of hot flashes for men on androgen deprivation therapy: results of a randomized double-blind placebo controlled trial

    PubMed Central

    Al-Bareeq, Reem J.; Ray, A. Andrew; Nott, Linda; Pautler, Stephen E.; Razvi, Hassan

    2010-01-01

    Objective: To determine whether Dong Quai, a Chinese herbal compound purported to be efficacious in treating menopausal vasomotor symptoms, has a therapeutic benefit in treating hot flashes among prostate cancer patients receiving androgen deprivation therapy. Methods: A randomized double-blind placebo controlled trial was conducted involving 22 men receiving luteinizing hormone-releasing hormone agonist therapy for prostate cancer with bothersome hot flashes. After recording a baseline log of the frequency, duration and severity of daily hot flashes, patients were randomly assigned in a 1:1 ratio to receive daily placebo or Dong Quai for 3 months. Vasomotor and adverse events were recorded daily. Blood work including serum prostate-specific antigen (PSA), international normalized ratio of prothrombin time and partial thromoboplastin time were recorded at baseline and at the termination of the study. Results: Seventeen of the 22 patients enrolled completed the trial. Baseline vasomotor duration and severity were equivalent between the groups, however the number of hot flashes were significantly more in the Dong Quai group (p = 0.02). With respect to the change in number of hot flashes per day, there was a slight decrease in the mean number among the Dong Quai group which was insignificant. The absolute change and average percentage change in perceived hot flash severity was similar in both groups. There was no significant decrease in the duration of the hot flashes between the 2 groups. Disease progression based on either PSA increase or change in digital rectal exam was not observed in any patient. Conclusion: In this small pilot study, there were no significant differences in the severity, frequency or duration of hot flashes among men receiving placebo or Dong Quai. PMID:20165579

  3. Potentiation of warfarin by dong quai.

    PubMed

    Page, R L; Lawrence, J D

    1999-07-01

    Dong quai is a Chinese herbal supplement touted for treatment of menstrual cramping, irregular menses, and menopausal symptoms. Phytochemical analyses found it to consist of natural coumarin derivatives, as well as constituents possessing antithrombotic, antiarrhythmic, phototoxic, and carcinogenic effects. A 46-year-old African-American woman with atrial fibrillation stabilized on warfarin experienced a greater than 2-fold elevation in prothrombin time and international normalized ratio after taking dong quai concurrently for 4 weeks. No identifiable cause was ascertained for the increase except dong quai. The patient's coagulation values returned to acceptable levels 1 month after discontinuing the herb. One animal study suggests a pharmacodynamic interaction between the product and warfarin, but the true mechanism remains unknown. Practitioners should be aware of the possibility of such an interaction and should inform patients of potential hazards of taking the two together. PMID:10417036

  4. Application of combined approach to analyze the constituents of essential oil from Dong quai.

    PubMed

    Huang, Lan-Fang; Li, Bo-Yan; Liang, Yi-Zeng; Guo, Fang-Qiu; Wang, Ya-Li

    2004-01-01

    A combined approach of sub-window factor analysis and spectral correlative chromatography has been employed to analyze the constituents of essential oils of Dong quai. Essential oils are the main pharmacological active individuals of Dong quai. Some constituents in the main root of Dong quai have been identified by GC-MS with the help of sub-window factor analysis resolving two-dimensional original data into mass spectra and chromatograms. Correlative constituents in another part of the root fiber have been recognized by spectral correlative chromatography. Seventy six of 97 separated constituents in the essential oil of main root were identified and quantified, accounting for about 91.36% of the total content. Sixty seven correlative components in the essential oil of root fiber were recognized. The result proves that the combined approach is powerful enough for the analysis of complex herbal samples. PMID:14658022

  5. Angelica sinensis polysaccharide induces erythroid differentiation of human chronic myelogenous leukemia k562 cells.

    PubMed

    Wang, Lu; Jiang, Rong; Song, Shu-Dan; Hua, Zi-Sen; Wang, Jian-Wei; Wang, Ya-Ping

    2015-01-01

    Leukemia is a clonal disorder with blocked normal differentiation and cell death of hematopoietic progenitor cells. Traditional modalities with most used radiation and chemotherapy are nonspecific and toxic which cause adverse effects on normal cells. Differentiation inducing therapy forcing malignant cells to undergo terminal differentiation has been proven to be a promising strategy. However, there is still scarce of potent differentiation inducing agents. We show here that Angelica sinensis polysaccharide (ASP), a major active component in Dong quai (Chinese Angelica sinensis), has potential differentiation inducing activity in human chronic erythro- megakaryoblastic leukemia K562 cells. MTT assays and flow cytometric analysis demonstrated that ASP inhibited K562 cell proliferation and arrested the cell cycle at the G0/G1 phase. ASP also triggered K562 cells to undergo erythroid differentiaton as revealed by morphological changes, intensive benzidine staining and hemoglobin colorimetric reaction, as well as increased expression of glycophorin A (GPA) protein. ASP induced redistribution of STAT5 protein from the cytoplasm to the nucleus. Western blotting analysis further identified that ASP markedly sensitized K562 cells to exogenous erythropoietin (EPO) by activating EPO-induced JAK2/ STAT5 tyrosine phosphorylation, thus augmenting the EPO-mediated JAK2/STAT5 signaling pathway. On the basis of these findings, we propose that ASP might be developed as a potential candidate for chronic myelogenous leukemia inducing differentiation treatment. PMID:25987027

  6. Senescence effects of Angelica sinensis polysaccharides on human acute myelogenous leukemia stem and progenitor cells.

    PubMed

    Liu, Jun; Xu, Chun-Yan; Cai, Shi-Zhong; Zhou, Yue; Li, Jing; Jiang, Rong; Wang, Ya-Ping

    2014-01-01

    Leukemia stem cells (LSCs) play important roles in leukemia initiation, progression and relapse, and thus represent a critical target for therapeutic intervention. Hence, it is extremely urgent to explore new therapeutic strategies directly targeting LSCs for acute myelogenous leukemia (AML) therapy. We show here that Angelica sinensis polysaccharide (ASP), a major active component in Dong quai (Chinese Angelica sinensis), effectively inhibited human AML CD34+CD38? cell proliferation in vitro culture in a dose-dependent manner while sparing normal hematopoietic stem and progenitor cells at physiologically achievable concentrations. Furthermore, ASP exerted cytotoxic effects on AML K562 cells, especially LSC-enriched CD34+CD38? cells. Colony formation assays further showed that ASP significantly suppressed the formation of colonies derived from AML CD34+CD38? cells but not those from normal CD34+CD38? cells. Examination of the underlying mechanisms revealed that ASP induced CD34+CD38? cell senescence, which was strongly associated with a series of characteristic events, including up-regulation of p53, p16, p21, and Rb genes and changes of related cell cycle regulation proteins P16, P21, cyclin E and CDK4, telomere end attrition as well as repression of telomerase activity. On the basis of these findings, we propose that ASP represents a potentially important agent for leukemia stem cell-targeted therapy. PMID:24377566

  7. [A new phthalide from angelicae sinensis radix].

    PubMed

    Niu, Yan; Wang, Shu-Fang

    2014-01-01

    Angelicae Sinensis Radix, dried roots of Angelicae sinensis, is a well-known traditional Chinese medicine. Six compounds were isolated and purified by silica gel and preparative HPLC. According to physicochemical properties and spectral data, the compounds were identified as senkyunolide H-7-acetate (1), o-phthalic acid (2), diisobutyl phthalate (3), p-hydroxyphenylethanol ferulate (4), ferulic acid (5) and coniferylferulate (6). Compound 1 was a new one. PMID:24754173

  8. Quantitative Analysis of Marker Compounds in Angelica gigas, Angelica sinensis, and Angelica acutiloba by HPLC/DAD.

    PubMed

    Jeong, Su Yang; Kim, Hye Mi; Lee, Kyu Ha; Kim, Kyu Yeob; Huang, Dae Sun; Kim, Jong Hwan; Seong, Rack Seon

    2015-07-01

    Although Danggui is the root of Angelica gigas NAKAI in the Korean Pharmacopoeia, it is determined that Danggui is also the root of Angelica sinensis (OLIV.) DIELS in China and Hong Kong, as well as the root of Angelica acutiloba KITAGAWA in Japan. Accordingly, we tried to develop an identification method using the main compounds in A. gigas, A. sinensis, and A. acutiloba through HPLC/diode-array detector (DAD). This method was fully validated for linearity, accuracy, precision, recovery, and robustness. Multivariate analysis was also implemented after pattern analysis and monitoring. As a result, each compound pattern of A. gigas, A. sinensis, and A. acutiloba was identified, making it possible to distinguish them from each other. PMID:25946978

  9. [Antimutagenic properties of Angelica archangelica L].

    PubMed

    Salikhova, R A; Poroshenko, G G

    1995-01-01

    The antimutagenic activity of Angelica archangelica L. aqueous and alcohol extracts of thio-TEPA against mutagenicity was examined by the micronucleus test in murine bone marrow cells. The reduction of Thio-TEPA's mutagenic activity was more profound when the extracts were injected 2 hours before thio-TEPA treatment, as seen during simultaneous treatment. The observed reduction of micronuclear frequencies was as high as 77%. PMID:7767122

  10. [Quality control of Angelica sinensis with standard reference extract].

    PubMed

    Xi, Jun-Zuan; Qian, Yi-Yun; Duan, Jin-Ao; Yan, Hui; Zhao, Yu-Yang; Zhang, Jie; Guo, Ling; Qian, Da-Wei

    2014-10-01

    To improve the quality standard of Angelica sinensis, solve the problem of lacking relevant reference substance, a new method-based on the standard reference extract (SRE) was applied to achieve the quality control of Angelica sinensis. SRE of Angelica sinensis was obtained by chromatographic separation technology. After calibration of three makers of the SRE, an UPLC analytical method was developed to determinate the contents of the makers. T-test was used for comparison of the determination results of two methods (reference substances and SRE as reference, respectively), and the results demonstrated that there is no significant difference between the two methods. The presented method is very convenient and practical, which can be used for the quality control of Angelica sinensis. PMID:25612444

  11. Phytochemical progress made in investigations of Angelica sinensis (Oliv.) Diels.

    PubMed

    Ma, Jian-Ping; Guo, Zhi-Bing; Jin, Ling; Li, Ying-Dong

    2015-04-01

    The phytochemical progress on Angelica sinensis (Oliv.) Diels over the past decades is summarized. Since 1970s, 165 chemical constituents, including phthalides, phenylpropanoids, terpenoids and essential oils, aromatic compounds, alkaloids, alkynes, sterols, fatty acids, and polysaccharides have been isolated or detected from the various parts of the title plant. PMID:25908620

  12. Determination of ferulic acid and adenosine in Angelicae Radix by micellar electrokinetic chromatography

    Microsoft Academic Search

    Tao Guo; Yi Sun; Yin Sui; Famei Li

    2003-01-01

    A micellar electrokinetic chromatography for determining ferulic acid and adenosine in Angelicae Radix was developed. A buffer solution composed of 50 mmol Lу borax, 10 mmol Lу sodium deoxycholate, and 2% methanol was found to be the most suitable electrolyte for the separation. The contents of ferulic acid and adenosine in Angelicae Radix were determined within 20 min. Good linearity

  13. Polysaccharides from Angelica sinensis alleviate neuronal cell injury caused by oxidative stress.

    PubMed

    Lei, Tao; Li, Haifeng; Fang, Zhen; Lin, Junbin; Wang, Shanshan; Xiao, Lingyun; Yang, Fan; Liu, Xin; Zhang, Junjian; Huang, Zebo; Liao, Weijing

    2014-02-01

    Angelica sinensis has antioxidative and neuroprotective effects. In the present study, we aimed to determine the neuroprotective effect of polysaccharides isolated from Angelica sinensis. In a preliminary experiment, Angelica sinensis polysaccharides not only protected PC12 neuronal cells from H2O2-induced cytotoxicity, but also reduced apoptosis and intracellular reactive oxygen species levels, and increased the mitochondrial membrane potential induced by H2O2 treatment. In a rat model of local cerebral ischemia, we further demonstrated that Angelica sinensis polysaccharides enhanced the antioxidant activity in cerebral cortical neurons, increased the number of microvessels, and improved blood flow after ischemia. Our findings highlight the protective role of polysaccharides isolated from Angelica sinensis against nerve cell injury and impairment caused by oxidative stress. PMID:25206810

  14. Polysaccharides from Angelica sinensis alleviate neuronal cell injury caused by oxidative stress

    PubMed Central

    Lei, Tao; Li, Haifeng; Fang, Zhen; Lin, Junbin; Wang, Shanshan; Xiao, Lingyun; Yang, Fan; Liu, Xin; Zhang, Junjian; Huang, Zebo; Liao, Weijing

    2014-01-01

    Angelica sinensis has antioxidative and neuroprotective effects. In the present study, we aimed to determine the neuroprotective effect of polysaccharides isolated from Angelica sinensis. In a preliminary experiment, Angelica sinensis polysaccharides not only protected PC12 neuronal cells from H2O2-induced cytotoxicity, but also reduced apoptosis and intracellular reactive oxygen species levels, and increased the mitochondrial membrane potential induced by H2O2 treatment. In a rat model of local cerebral ischemia, we further demonstrated that Angelica sinensis polysaccharides enhanced the antioxidant activity in cerebral cortical neurons, increased the number of microvessels, and improved blood flow after ischemia. Our findings highlight the protective role of polysaccharides isolated from Angelica sinensis against nerve cell injury and impairment caused by oxidative stress. PMID:25206810

  15. [Discrimination of polysaccharides from Angelica sinensis and its different processed products based on fourier transform infrared spectroscopy].

    PubMed

    Ji, Peng; Wei, Yan-Ming; Hua, Yong-Li; Zhang, Wen-quan

    2014-05-01

    A new rapid and nondestructive method for identifying polysaccharides from Angelica sinensis and its different processed products was developed, and this method was based on Fourier transform infrared spectroscopy (FTIR). In the clinic of traditional Chinese medicine, unprocessed Angelica sinensis(UAS) is of ten used after processed, the common processed products are Angelica sinensis parched with wine(WAS), Angelica sinensis parched with soil(SAS), Angelica sinensis parched with oil(OAS) and Charred Angelica sinensis(CAS). In order to use polysaccharides from Angelica sinensis and its processed products effectively and reasonably in clinic, it is very necessary to identify them. FTIR of polysaccharides from Angelica sinensis and its different processed products was determined, and then it was decomposed by discrete wavelet transform (DWT). The high frequency information in scale 2, 3 and 4 was selected as feature information, from which the each wavelet entropy was extracted as characteristic value. BP neural network was trained with these characteristic values. The trained BP neural network was used to identify polysaccharides from Angelica sinensis and its different processed products. According to 30 prediction samples, the correct rate for recognition was 93. 3%, which indicates that: it has better feasibility to identify polysaccharides from Angelica sinensis and its different processed products by this method, which is based on FTIR, discrete wavelet transform and BP neural network PMID:25095420

  16. Phytochemical and pharmacological studies on Radix Angelica sinensis.

    PubMed

    Chen, Xiao-Peng; Li, Wei; Xiao, Xue-Feng; Zhang, Lan-Lan; Liu, Chang-Xiao

    2013-11-01

    The roots of Angelica sinensis (RAS), are a Chinese herbal medicine traditionally used in prescriptions for replenishing blood, treating abnormal menstruation, and other women's diseases. It has also been widely marketed as health food for women's care in Asia, and as a dietary supplement in Europe and America. RAS is well-known for its hematopoietic, antioxidant, and immunoregulatory activities. RAS also possesses anti-cancer, memory, radioprotective, and neuroprotective effects. Phytochemical investigations on this plant led to organic acids, phthalides, polysaccharides, and other metabolites. Based on recent animal studies and clinical trials, RAS has been used in the treatment of gynecologic diseases, cardio-cerebrovascular disease, nervous system diseases, and nephrotic syndrome. In this review, the recent phytochemical and pharmacological studies, drug-drug interactions, clinical applications, and toxicity of RAS are summarized. PMID:24345498

  17. Angelica sinensis and osteoarthritis: a natural therapeutic link?

    PubMed

    Magdalou, Jacques; Chen, Liao-Bin; Wang, Hui; Qin, Jun; Wen, Yingxian; Li, Xiao-Jun; Shang, Liang; Li, Jing

    2015-01-01

    The dried root of Angelica sinensis is widely used in Chinese traditional medicine for its beneficial effects against several diseases, including osteoarthritis. In order to understand the mechanism of action, two main components of the plant, the phytochemical, sodium ferulate, and a polysaccharidic fraction have been tested on osteoarthritis animal models or in human chondrocytes stimulated by the pro-inflammatory cytokine, Interleukine-1?. The results showed that sodium ferulate exhibited marked anti-inflammatory and anti-apoptotic properties by inhibiting the TNF/TNFR signal transduction pathway. On the other hand, the polysaccharidic fraction which contains a mixture of various carbohydrates was found to promote proteoglycan biosynthesis in cartilage matrix by stimulating the activity of the UDP-glycosyltransferases that synthesize the chondroitin sulfate chains of aggrecans. It is suggested that the combined action of sodium ferulate and polysaccharidic fraction would prevent cartilage destruction in osteoarthritis and favor cartilage repair. PMID:25538068

  18. Molecular and phytochemical investigation of Angelica dahurica and Aneelica pubescentis essential oils and their biological activity against Aedes aegypti, Stephanitis pyrioides and Colletotrichum species

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Water distilled essential oils from the roots of Angelica dahurica and Angelica pubescentis were investigated for their antifungal activity against plant pathogens Colletotrichum acutatum, C. fragariae, and C. gloeosporioides as well as insecticidal activity against the yellow fever mosquito, Aedes ...

  19. Molecular systematics of Angelica and allied genera (Apiaceae) from the Hengduan Mountains of China based on nrDNA ITS sequences: phylogenetic affinities and biogeographic implications

    Microsoft Academic Search

    Tu Feng; Stephen R. Downie; Yan Yu; Xuemei Zhang; Weiwei Chen; Xingjin He; Shuang Liu

    2009-01-01

    Maximum parsimony, maximum likelihood, and Bayesian analyses of nuclear ribosomal DNA internal transcribed spacer sequences\\u000a were used to infer the phylogenetic affinities and historical biogeography of Angelica and its allies (Apiaceae tribe Selineae), with emphasis on those species of Angelica and Peucedanum endemic to the Hengduan Mountains of south-central China. Results of these analyses corroborate a monophyletic Angelica (Angelica sensu

  20. Bioactivity-Guided Fractionation and GC/MS Fingerprinting of Angelica sinensis and Angelica archangelica Root Components for Antifungal and Mosquito Deterrent Activity

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Angelica sinensis and A. archangelica belong to the Umbelliferae and both are used in traditional Chinese medicine to treat gynecological and intestinal disorders. In this study, oils from three different A. sinensis collections and one A. archangelica root were analyzed by GC and GC/MS. The domin...

  1. Biomechanics and Biomaterials Research Center Hiroki Yokota and Dong Xie

    E-print Network

    Zhou, Yaoqi

    Biomechanics and Biomaterials Research Center Hiroki Yokota and Dong Xie School of Engineering and Technology Indiana University ­ Purdue University Indianapolis Abstract The Biomechanics and Biomaterials

  2. In vitro neuroprotective activities of compounds from Angelica shikokiana Makino.

    PubMed

    Mira, Amira; Yamashita, Shuntaro; Katakura, Yoshinori; Shimizu, Kuniyoshi

    2015-01-01

    Angelica shikokiana is widely marketed in Japan as a dietary food supplement. With a focus on neurodegenerative conditions such as Alzheimer's disease, the aerial part was extracted and through bio-guided fractionation, fifteen compounds [?-glutinol, ?-amyrin, kaempferol, luteolin, quercetin, kaempferol-3-O-glucoside, kaempferol-3-O-rutinoside, methyl chlorogenate, chlorogenic acid, hyuganin E, 5-(hydroxymethyl)-2-furaldehyde, ?-sitosterol-3-O-glucoside, adenosine (isolated for the first time from A. shikokiana), isoepoxypteryxin and isopteryxin] were isolated. Isolated compounds were evaluated for in vitro neuroprotection using acetylcholine esterase inhibitory, protection against hydrogen peroxide and amyloid ? peptide (A?25-35)-induced neurotoxicity in neuro-2A cells, scavenging of hydroxyl radicals and intracellular reactive oxygen species and thioflavin T assays. Quercetin showed the strongest AChE inhibition (IC50 value = 35.5 µM) through binding to His-440 and Tyr-70 residues at the catalytic and anionic sites of acetylcholine esterase, respectively. Chlorogenic acid, its methyl ester, quercetin and luteolin could significantly protect neuro-2A cells against H2O2-induced neurotoxicity and scavenge hydroxyl radical and intracellular reactive oxygen species. Kaempferol-3-O-rutinoiside, hyuganin E and isoepoxypteryxin significantly decreased A?25-35-induced neurotoxicity and Th-T fluorescence. To the best of our knowledge, this is the first report about neuroprotection of hyuganin E and isoepoxypteryxin against A?25-35-induced neurotoxicity. PMID:25786165

  3. [Study of the antimutagenic properties of Angelica archangelica by the micronucleus test].

    PubMed

    Salikhova, R A; Dulatova, Sh N; Poroshenko, G G

    1993-04-01

    The antimutagenic activity Angelica archangelica L. water and alcohol extracts thio-tepa against mutagenicity was investigated by the micronucleus test in mouse bone marrow and peripheral blood cells. The reduction of thio-tepa mutagenic activity was more prominent when the extracts were injected 2-hours before thio-tepa treatment as it could be seen at the simultaneous treatment. The observed reduction of micronucleus frequencies was up to 77%. No genotoxic effects of Angelica extracts had been seen at the concentrations 50-100 mg/kg. PMID:8049396

  4. Herb-drug interactions

    Microsoft Academic Search

    Adriane Fugh-Berman

    Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin,

  5. Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications.

    PubMed

    Zhang, Wendy Li; Zheng, Ken Yu-Zhong; Zhu, Kevin Yue; Zhan, Janis Ya-Xian; Bi, Cathy Wen-Chuan; Chen, Jian-Ping; Du, Crystal Ying-Qing; Zhao, Kui-Jun; Lau, David Tai-Wai; Dong, Tina Ting-Xia; Tsim, Karl Wah-Keung

    2012-08-15

    The commonly used Angelica herbal decoction today is Danggui Buxue Tang (DBT), which is a dietary supplement in treating menopausal irregularity in women, i.e. to nourish "Qi" and to enrich "Blood". According to historical record, many herbal decoctions were also named DBT, but the most popular formulation of DBT was written in Jin dynasty (1247 AD) of China, which contained Astragali Radix (AR) and Angelicae Sinensis Radix (ASR) with a weight ratio of 5:1. However, at least two other Angelica herbal decoctions recorded as DBT were prescribed in Song (1155 AD) and Qing dynasties (1687 AD). Although AR and ASR are still the major components in the DBT herbal decoctions, they are slightly varied in the herb composition. In order to reveal the efficiency of different Angelica herbal decoctions, the chemical and biological properties of three DBT herbal extracts were compared. Significantly, the highest amounts of AR-derived astragaloside III, astragaloside IV, calycosin and formononetin and ASR-derived ferulic acid were found in DBT described in 1247 AD: this preparation showed stronger activities in osteogenic, estrogenic and erythropoetic effects than the other two DBT. The current results supported the difference of three DBT in chemical and biological properties, which could be a result of different herbal combinations. For the first time, this study supports the popularity of DBT described in 1247 AD. PMID:22902230

  6. Chromatographic and mass spectrometric fingerprinting analyses of angelica sinensis (Oliv.) diels dietary supplements

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Angelica sinensis (Oliv.) Diels (“Danggui” in Chinese) is one of the most commonly used Traditional Chinese Medicines (TCMs). It has been used to invigorate blood circulation for the treatment of anemia, hypertension, chronic bronchitis, asthma, rheumatism and cardiovascular diseases. There are a lo...

  7. Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect.

    PubMed

    Choi, Kyeong-Ok; Lee, Inae; Paik, Sae-Yeol-Rim; Kim, Dong Eun; Lim, Jung Dae; Kang, Wie-Soo; Ko, Sanghoon

    2012-10-01

    The root of Angelica gigas (Korean angelica) is traditionally used to treat women's ailments that are caused by an impairment of menstrual blood flow and cycle irregularities. This study evaluated the effect particle size of Korean angelica powder on its efficacy for treating estrogen-related symptoms of menopause. Initially, Korean angelica roots were pulverized into ultrafine powder, and orally administered to the rats at a concentration of 500 mg/kg body weight for 8 weeks. The effects of Korean angelica powder particle size on extraction yield, contents of bioactive compounds (decursin and decursinol angelate), levels of serum ovarian hormones (estradiol and progesterone), reproductive hormones (luteinizing hormone and follicle-stimulating hormone), and experimental osteoporosis parameters (mineral density, strength, and histological features) were determined. A significant increase (fivefold) in the contents of decursin and decursinol angelate in the extract of the ultrafine Korean angelica powder was observed compared to coarse Korean angelica powder. Rats were divided into sham-operated or ovariectomized (OVX) groups that were fed coarse (CRS) or ultrafine (UF) ground Korean angelica root. The serum levels of estradiol in the OVX_UF group were 19.2% and 54.1% higher than that of OVX_CRS group. Serum bone-alkaline phosphatase/total-alkaline phosphatase index in the OVX_UF group was half that of the OVX_CRS group. In addition, less trabecular bone loss and thick cortical areas were observed in rats administered ultrafine powder. Therefore, ultrafine grinding may enhance the bioactivity of herbal medicines and be especially useful when their extracted forms lose bioactivity during processing, storage, and oral intake. PMID:23039111

  8. Assessment of Young Dong tributary and Imgok Creek impacted by Young Dong coal mine, South Korea.

    PubMed

    Lee, Byung-Tae; Ranville, James F; Wildeman, Thomas R; Jang, Min; Shim, Yon Sik; Ji, Won Hyun; Park, Hyun Sung; Lee, Hyun Ju

    2012-01-01

    An initial reclamation of the Young Dong coal mine site, located in northeastern South Korea, was completed in 1995. Despite the filling of the adit with limestone, acid rock drainage (ARD) enters Young Dong tributary and is then discharged to Imgok Creek. This ARD carries an average of 500 mg CaCO(3)/l of mineral acidity, primarily as Fe(II) and Al. Before spring runoff, the flow of Imgok Creek is 3.3-4 times greater than that of the tributary and has an alkalinity of 100 mg CaCO(3)/l, which is sufficient to eliminate the mineral acidity and raise the pH to about 6.5. From April through September 2008, there were at least two periods of high surface flow that affects the flow of ARD from the adit. Flow of ARD reaches 2.8 m(3)/min during spring runoff. This raised the concentrations of Fe and Al in the confluence with Imgok Creek. However, by 2 km downstream the pH of the Imgok Creek is 6.5 and only dissolved Fe is above the Korean drinking water criteria (0.30 mg/l). This suggests only a minor impact of Young Dong Creek water on Imgok Creek. Acid digestion of the sediments in Imgok Creek and Young Dong Tributary reveals considerable abundances of heavy metals, which could have a long-term impact on water quality. However, several water-based leaching tests, which better simulate the bioavailable metals pool, released only Al, Fe, Mn, and Zn at concentrations exceeding the criteria for drinking water or aquatic life. PMID:21818559

  9. Biocontrol of Phytophthora Root Rot of Angelica Trees by Enterobacter cloacae and Serratia ficaria Strains

    Microsoft Academic Search

    Hiroshi OKAMOTO; Mamoru SATO; Yoshio MIYATA; Masami YOSHIKAWA; Makoto ISAKA

    2000-01-01

      Bacterial strains isolated from the rhizosphere of angelica trees were evaluated for their antagonistic activity against Phytophthora cactorum, a causal agent of Phytophthora root rot. Of these, three bacterial strains, designated as T-1-8, T-1-14 and T-1-23, strongly inhibited mycelial growth of\\u000a P. cactorum ARE-862 in a dual-culture plate assay. Biocontrol activity of these strains was then examined by dipping root

  10. Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships.

    PubMed

    Kang, S Y; Lee, K Y; Sung, S H; Park, M J; Kim, Y C

    2001-05-01

    Acetylcholinesterase (AChE) inhibitory activity-guided fractionation of Angelica gigas led to isolation and identification of a new coumarin, peucedanone (12), and isolation of 11 known coumarins. Among them, decursinol (1) represented the highest inhibitory activity toward AChE in vitro. The correlation of the inhibitory activities of the coumarins toward AChE with their chemical structures was studied. PMID:11374978

  11. Bioactivity-guided fractionation and GC/MS fingerprinting of Angelica sinensis and Angelica archangelica root components for antifungal and mosquito deterrent activity.

    PubMed

    Wedge, David E; Klun, Jerome A; Tabanca, Nurhayat; Demirci, Betul; Ozek, Temel; Baser, Kemal Husnu Can; Liu, Zhijun; Zhang, Sui; Cantrell, Charles L; Zhang, Jian

    2009-01-28

    Bioassay-guided fractionation of the chloroform extract from the roots of Angelica sinensis led to isolation and characterization of (Z)-ligustilide using direct-bioautography with Colletotrichum species. The structure of (Z)-ligustilide was confirmed by (1)H and (13)C NMR spectroscopy and GC/MS. (Z)-Ligustilide deterred the biting of two mosquito species more effectively than DEET. Three different A. sinensis accessions and one Angelica archangelica root oil were evauated by GC and GC/MS, and the dominant component in A. sinensis was 61-69% (Z)-ligustilide. Two other prominent compounds in A. sinensis oils were 5.7-9.8% (E)-3-butylidene phthalide and 1.5-2.3% (Z)-3-butylidene phthalide. The main constituents that comprised A. archangelica oil were monoterpene hydrocarbons such as 24.5% alpha-pinene, 13.8% delta-3-carene, 10.1% beta-phellandrene, 8.8% p-cymene, 8.4% limonene, and 6.3% sabinene. Phthalides and monoterpene hydrocarbons were determined to be good systematic markers or chemical fingerprints for A. sinensis and A. archangelica root oils. Chemical fingerprinting by GC/MS of A. sinensis also confirmed the misidentification of one A. archangelica sample sold in the Chinese market. PMID:19113871

  12. In vivo anthelmintic activity of crude extracts of Radix angelicae pubescentis , Fructus bruceae , Caulis spatholobi , Semen aesculi , and Semen pharbitidis against Dactylogyrus intermedius (Monogenea) in goldfish ( Carassius auratus )

    Microsoft Academic Search

    You-Tao Liu; Fan Wang; Gao-Xue Wang; Jing Han; Yong Wang; Yong-Hua Wang

    2010-01-01

    In search of a natural antiparasitic, in vivo anthelmintic activity of petroleum ether, chloroform, ethyl acetate, methanol,\\u000a and aqueous extracts of Angelica pubescens roots (Radix angelicae pubescentis), Brucea javanica fruits (Fructus bruceae), Spatholobus suberectus stems (Caulis spatholobi), Aesculus chinensis Bge. seeds (Semen aesculi), and Pharbitis purpurea (L.) Voigt seeds (Semen pharbitidis) were tested against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius

  13. Enhancement of pheochromocytoma nerve cell growth by consecutive fractionization of Angelica gigas Nakai extracts

    PubMed Central

    Jeong, Myoung Hoon; Kim, Ji Seon; Zou, Yunyun; Yoon, Chang Soon; Lim, Hye Won; Ahn, Juhee

    2010-01-01

    This work was to investigate the effect of flavonoids from Angelica gigas Nakai on the proliferation and differentiation of PC12 cells. Several solvents including hexane, chloroform, ethyl acetate, butanol and water consecutively partitioned. We determined the ethanol crude extract of Angelica gigas Nakai. The hexane fraction was shown to contain the highest number of flavonoids as follows; 21.48 mg/g and the composition of the flavonoids was as follows: 12.24 mg/g of quercetin, 4.39 mg/g of myricetin and 2.58 mg/g of catechin. In addition, this hexane fraction greatly increased both cell growth and outgrowth of the neurite, and whose effects were three times higher than those of the other fractions. The length of the neurites was measured as ca. 110 ?m in adding 50 ?g/mL of the hexane fraction, which was about the same as the case of adding 50 ng/mL of NGF as a positive control. This result indicates that the differentiation of PC12 cells by the addition of the hexane fraction was comparable to the case of adding NGF. The hexane fraction was also determined to prevent apoptosis of PC12 cells by suppressing DNA fragmentation. It is interesting that the mixture of three major flavonoids, quercetin, myricetin and catechin showed stronger activity on, both PC12 cell growth and neuritis outgrowth, than when adding each flavonoid alone. We believe this was due to the synergistic effects of the three flavonoids. The activities of these flavonoids from Angelica gigas Nakai are reported for the first time in this study. PMID:20936343

  14. MAXIMA IN HYPERCUBES Zhi-Dong Bai1

    E-print Network

    Tsai, Tsung-Hsi

    MAXIMA IN HYPERCUBES Zhi-Dong Bai1 College of Mathematics and Statistics Northeast Normal, and has been widely used in many scientific disciplines; see Bai et al. (1998, 2001), Chen et al. (2003 nontrivial even in the simplest case of hypercubes; see Bai et al. (1998). Baryshnikov (2000) indicated

  15. MAXIMA IN HYPERCUBES ZhiDong Bai 1

    E-print Network

    Devroye, Luc

    MAXIMA IN HYPERCUBES Zhi­Dong Bai 1 College of Mathematics and Statistics Northeast Normal, and has been widely used in many scientific disciplines; see Bai et al. (1998, 2001), Chen et al. (2003 nontrivial even in the simplest case of hypercubes; see Bai et al. (1998). Baryshnikov (2000) indicated

  16. Spreading of energy in the Ding-Dong model

    NASA Astrophysics Data System (ADS)

    Roy, S.; Pikovsky, A.

    2012-06-01

    We study the properties of energy spreading in a lattice of elastically colliding harmonic oscillators (Ding-Dong model). We demonstrate that in the regular lattice the spreading from a localized initial state is mediated by compactons and chaotic breathers. In a disordered lattice, the compactons do not exist, and the spreading eventually stops, resulting in a finite configuration with a few chaotic spots.

  17. MODELING INTERACTIONS FROM EMAIL COMMUNICATION Dong Zhang1

    E-print Network

    Roy, Deb

    MODELING INTERACTIONS FROM EMAIL COMMUNICATION Dong Zhang1 , Daniel Gatica-Perez1 , Deb Roy2 Massachusetts Institute of Technology, Cambridge, MA 02142, USA ABSTRACT Email plays an important role to learn topic-based interactions between pairs of email users, i.e., the extent to which the email topic

  18. Flood Operation Rules for a Single Reservoir Licheng Dong

    E-print Network

    Lund, Jay R.

    Flood Operation Rules for a Single Reservoir Licheng Dong MS Degree Paper Civil and Environmental. These rules are: 1) optimal peak reduction with perfect foreknowledge of the flood hydrograph; 2) minimized operation rules with incomplete foreknowledge of the flood hydrograph are likely to work better

  19. A Study of the Phaonia angelicae Group (Diptera: Muscidae), with Descriptions of Six New Species from China

    PubMed Central

    Xue, Wan-Qi; Zhang, Xiang

    2013-01-01

    The P. angelicae group from China was studied, and six new species are described: P. hanmiensis, n. sp., P. nanlingensis, n. sp., P. reduncicauda, n. sp., P. spargocerca, n. sp., P. subincana, n. sp., and P. varimargina, n. sp. A key to the identification of males of the 40 Chinese species is given. PMID:24773293

  20. Simultaneous quantification of six main active constituents in Chinese Angelica by high-performance liquid chromatography with photodiode array detector

    PubMed Central

    Ying, Li; Si-Wang, Wang; Hong-Hai, Tu; Wei, Cao

    2013-01-01

    Background: Angelica sinensis is a famous traditional Chinese medicinalherb, which is predominantly used in the treatment of gynecological conditions. It is the first report for the simultaneous determination of six major active components in Chinese Angelica, which is important for quality control. Objective: A validated HPLC-PAD method was first developed to evaluate the quality of crude and processed Radix Angelica through simultaneous determination of six bioactive compounds, namely ferulic acid, senkyunolide I, senkyunolide H, coniferyl ferulate, Z/E-ligustilide and Z/E-butylidenephthalide. Materials and Methods: Samples were separated on a Xtimate™C18 column (250 × 4.6 mm, 5 ?m) and detected by PAD. Mobile phase was composed of (A) aqueous phosphoric acid (0.02%, v/v) and (B) acetonitrile (MeCN) (including 10% tetrahydrofuran, v/v) using a gradient elution. Analytes were performed at 30°C with a flow rate of 1.0 mL/min. Results: All calibration curves showed good linear regression (r2 ? 0.9963) within the tested ranges, and the recovery of the method was in the range of 91.927–105.859%. Conclusion: The results demonstrate that the developed method is accurate and reproducible and could be readily utilized as a suitable quality control method for the quantification of Radix Angelica. PMID:23772106

  1. [Investigation on chromatogram-pharmacodynamics relationship of Angelica sinensis on effect of replenishing blood].

    PubMed

    Yang, Ying-Lai; Cui, Fang; Hu, Fang; Guo, Long; Yang, Tao; Li, Ying-Dong; Feng, Shi-Lan

    2013-11-01

    Blood deficiency model of mice was copied by subcutaneous injection with 200, 100 and 100 mg x kg(-1) (0.01 mL x g(-1)) acetyl phenylhydrazine (APH) at the frist, fourth, and seventh days. Mice in each group were perfused with different extracted parts of Angelica sinensis (drug dosage was 2.4 g x kg(-1)) at the tenth day, once a day for 10 days. Then compare the influence of different extracted parts of Angelica sinensis to RBC, Hb, PLT and thymus, spleen and weight changes of blood deficiency mice. The peak areas of each common peak from HPLC fingerprint were associated with the date of replenishing blood pharmacodynamics efficacy by using gray relation statistic, which was used to research the chromatogram-pharmacodynamics relationship. The results showed that the part of DSC has the better effect in replenishing blood. The contribution degree of the DSC to replenishing blood of each component were determined by correlation size, and ferulic acid made the largest contribution, but contribution of other components should not be ignored. In this paper, we research the relationship of the HPLC fingerprint and spectrum activity relationship, determine the material basis of the DSC for replenishing blood, and provide effective way to represent the spectral correlation effect. PMID:24558877

  2. Characterization and antioxidative activities of polysaccharide in Chinese angelica and its processed products.

    PubMed

    Ji, Peng; Wei, Yanming; Xue, Wenxin; Hua, Yongli; Zhang, Man; Sun, Hongguo; Song, Zhixue; Zhang, Ling; Li, Jinxia; Zhao, Haifu; Zhang, Wenquan

    2014-06-01

    Five polysaccharides from unprocessed Chinese angelica (UCAP), parched one with alcohol (ACAP), soil (SCAP), sesame oil (OCAP) and parched into charred (CCAP) were extracted and purified. Their structures were identified by Fourier transform-infrared spectroscopy (FT-IR), compositions were analyzed by gas chromatography-mass spectrometry (GC-MS) and antioxidative activities were compared by determining MDA contents and SOD activities of liver tissue in mice damaged with CCl4 after gavage. The results showed that the FT-IR spectra of CCAP and OCAP displayed lower transmittance at around 1050cm(-1) in comparison with that of UCAP. Five polysaccharides were all composed of rhamnose, arabinose, mannose, glucose and galactose. In CCAP, ACAP, OCAP and SCAP, the proportions of arabinose were significantly increased in comparison with that of UCAP. The SOD activities in CCAP and SCAP groups were significantly enhanced, and MDA contents in CCAP, OCAP and SCAP groups were significantly decreased as compared with UCAP group. This indicated that processing could change the structure, composition and enhance antioxidative activity of polysaccharide in Chinese angelica, and CCAP possessed the strongest antioxidative activity. PMID:24680904

  3. Anti-Inflammatory Effect of Angelica gigas via Heme Oxygenase (HO)-1 Expression.

    PubMed

    Cho, Joon Hyeong; Kwon, Jung Eun; Cho, Youngmi; Kim, Inhye; Kang, Se Chan

    2015-01-01

    Angelica gigas (AG) is effective against various medical conditions such as bacterial infection, inflammation, and cancer. It contains a number of coumarin compounds and the group of interest is the pyranocoumarin, which comprises decursin and decursinol angelate. This group has an effect on controlling inflammation, which is caused by excessive nitric oxide (NO) production. Heme oxygenases (HOs), particularly HO-1, play a role in regulating the production of NO. Thus, this study aimed to investigate the anti-inflammatory effects of AG by measuring HO-1 expression. Treatments with CH2Cl2 layer and Angelica gigas extract (AGE) showed the highest NO inhibition effects. Decursin, decursinol angelate, and nodakenin were isolated from the CH2Cl2 layer of AGE. Decursin also demonstrated the highest anti-oxidative effect among the coumarins. Although decursin had the best NO inhibition and anti-oxidative effects, the effects of AGE treatment far surpassed that of decursin. This is owing to the combination effect of the coumarins present within AGE, which is a solvent extract of AG. The expression of HO-1 is an effective indicator of the anti-inflammatory effects of AG. Based on the results of the coumarin compounds, HO-1 expression was found to be dose dependent and specific to decursin. PMID:26083119

  4. Anti-Inflammatory Effect of Angelica gigas via Heme Oxygenase (HO)-1 Expression

    PubMed Central

    Cho, Joon Hyeong; Kwon, Jung Eun; Cho, Youngmi; Kim, Inhye; Kang, Se Chan

    2015-01-01

    Angelica gigas (AG) is effective against various medical conditions such as bacterial infection, inflammation, and cancer. It contains a number of coumarin compounds and the group of interest is the pyranocoumarin, which comprises decursin and decursinol angelate. This group has an effect on controlling inflammation, which is caused by excessive nitric oxide (NO) production. Heme oxygenases (HOs), particularly HO-1, play a role in regulating the production of NO. Thus, this study aimed to investigate the anti-inflammatory effects of AG by measuring HO-1 expression. Treatments with CH2Cl2 layer and Angelica gigas extract (AGE) showed the highest NO inhibition effects. Decursin, decursinol angelate, and nodakenin were isolated from the CH2Cl2 layer of AGE. Decursin also demonstrated the highest anti-oxidative effect among the coumarins. Although decursin had the best NO inhibition and anti-oxidative effects, the effects of AGE treatment far surpassed that of decursin. This is owing to the combination effect of the coumarins present within AGE, which is a solvent extract of AG. The expression of HO-1 is an effective indicator of the anti-inflammatory effects of AG. Based on the results of the coumarin compounds, HO-1 expression was found to be dose dependent and specific to decursin. PMID:26083119

  5. 14-Methylpentadecano-15-lactone (muscolide): a new macrocyclic lactone from the oil of Angelica archangelica L.

    PubMed

    Lopes, Daíse; Strobl, Herbert; Kolodziejczyk, Paul

    2004-12-01

    The chemical composition of seed and root oils from Angelica archangelica L. was investigated. Analyses were performed by GC/MS and GC using two columns of different polarities (polyethylene glycol (DB-Wax) and 5% phenyl/95% polydimethylsiloxane (HP-5)), for the separation of several co-eluting components. A total of 58 compounds were identified, accounting for 96.3% (seed) and 93.5% (root) of the oils, respectively. A high content of beta-phellandrene (74.7%) was found in Angelica seed oil. Root oil contained a larger amount of macrocyclic lactones (1.3%) in comparison to the seed oil (0.4%). Different harvest dates produced only slight changes in the root-oil composition. In root oil harvested in summer, the beta-phellandrene content increased by ca. 36%, but no significant changes in the relative compositions of other components were observed. Fresh root oils were collected in five fractions (constant time intervals) during steam distillation (see Table). The highest-boiling fraction contained 9.3% of macrocyclic lactones such as tridecano-13-lactone (5.0%), 12-methyltridecano-13-lactone (0.4%), tetradecano-14-lactone (0.1%), pentadecano-15-lactone (3.5%), 14-methylpentadecano-15-lactone (1; trace), hexadecano-16-lactone (trace), and heptadecano-17-lactone (0.2%). This is the first report of the occurrence of 14-methylpentadecano-15-lactone (muscolide; 1) in a natural product. PMID:17191826

  6. Identification and characterization of a new virus in the genus Potyvirus from wild populations of Angelica lucida L. and A. genuflexa Nutt., family Apiaceae

    Microsoft Academic Search

    N. L. Robertson

    2007-01-01

    Summary  A novel potyvirus was discovered in Angelica lucida L. (wild celery) and A. genuflexa Nutt. (kneeling Angelica) (family Apiaceae) in the Matanuska- Susitna Valley, Alaska. The experimental plant host range of the virus included species in three families:\\u000a Chenopodiaceae (Chenopodium amaranticolor Coste et Reyn and Chenopodium quinoa Willd.), Solanaceae (Nicotiana benthamiana Domin, and N. clevlandii Gray.), and Apiaceae (Anethum graveolens

  7. Evaluation of the effects of Angelicae dahuricae radix on the morphology and viability of mesenchymal stem cells.

    PubMed

    Jeong, Su-Hyeon; Kim, Bo-Bae; Lee, Ji-Eun; Ko, Youngkyung; Park, Jun-Beom

    2015-07-01

    Angelicae dahuricae radix is a traditional herbal medicine used to treat various diseases in China and Korea, such as colds, headaches, rhinitis and psoriasis. Angelicae dahuricae radix has been used as an anti?inflammatory, analgesic, antipyretic and antioxidant remedy. This study was performed in order to evaluate the effects of the extracts of Angelicae dahuricae radix on the morphology and viability of mesenchymal stem cells derived from the gingiva. Mesenchymal stem cells derived from the gingiva were grown in the presence of Angelicae dahuricae radix at final concentrations that ranged from 0.001 to 100 µg/ml. The morphology of the cells was viewed under an inverted microscope, and the analysis of cell proliferation was performed with cell counting kit?8 (CCK?8) on days 1, 3 and 7. The cells in the control group had spindle?shaped, fibroblast?like morphology at days 1, 3 and 7 under optical microscopy. The shapes of the cells in 0.001, 0.01, 0.1, 1, 10 and 100 µg/ml Angelicae dahuricae radix were similar to the shapes of the cells in the control group. The relative values of the CCK?8 assays of 0.001, 0.01, 0.1, 1, 10, and 100 µg/ml Angelicae dahuricae radix were 102.5±0.6, 133.3±9.6, 148.4±20.5, 147.7±12.6, 132.3±27.7 and 101.1±4.6%, respectively, when the CCK?8 result of the control group on day 1 was considered to be 100%. There was a marginal increase in cell proliferation at 0.1 and 1 µg/ml groups at day 1; however, this did not achieve statistical significance (P=0.052). The relative values of the CCK?8 assays of 0.001, 0.01, 0.1, 1, 10 and 100 µg/ml Angelicae dahuricae radix were 96.5±1.3, 89.3±0.9, 90.3±3.0, 84.8±12.2, 92.3±4.5 and 86.8±11.7%, respectively, when the CCK?8 result of the control group on day 3 was considered to be 100% (P>0.05). The relative values of the CCK?8 assays of 0.001, 0.01, 0.1, 1, 10 and 100 µg/ml Angelicae dahuricae radix day 7 were 94.9±22.3, 102.8±22.1, 127.4±7.4, 130.4±1.3, 129.2±10.8 and 124.8±9.1%, respectively, when the CCK?8 result of the control group on day 7 was considered to be 100%, but there were no statistically significant differences among the groups (P>0.05). Within the limits of this study, Angelicae dahuricae radix at the tested concentrations did not produce statistically significant differences in the viability of stem cells derived from the gingiva. PMID:25760069

  8. Spreading of energy in the Ding-Dong model.

    PubMed

    Roy, S; Pikovsky, A

    2012-06-01

    We study the properties of energy spreading in a lattice of elastically colliding harmonic oscillators (Ding-Dong model). We demonstrate that in the regular lattice the spreading from a localized initial state is mediated by compactons and chaotic breathers. In a disordered lattice, the compactons do not exist, and the spreading eventually stops, resulting in a finite configuration with a few chaotic spots. PMID:22757577

  9. Sciences SCIENCES II | QUAI ERNEST ANSERMET Accueil et collation ds 8h30

    E-print Network

    Citi, Sandra

    Sciences SCIENCES II | QUAI ERNEST ANSERMET Accueil et collation dès 8h30 Tous les étudiants: lundi 17 sep. 9h15 A Lettres UNI BASTIONS | RUE DE CANDOLLE Bachelor 1re année: vendredi 14 sep. 9h-11h B Master: mardi 18 sep. 17h30-18h30 salle à préciser Des séances d'information par discipline sont

  10. Sciences SCIENCES II | QUAI ERNEST ANSERMET Accueil et collation ds 8h30

    E-print Network

    Halazonetis, Thanos

    Sciences SCIENCES II | QUAI ERNEST ANSERMET Accueil et collation dès 8h30 Tous les étudiants: lundi 16 sep. 9h15 A Lettres UNI BASTIONS | RUE DE CANDOLLE Bachelor 1re année: vendredi 13 sep. 10h-12h B CANDOLLE * Ecole de langue et de civilisation françaises Année propédeutique: lundi 16 sep. 9h-12h B

  11. Fluorescence enhancement of radix angelica dahurica by binding to single silver sphere

    NASA Astrophysics Data System (ADS)

    Wang, Qing-Ru; Shi, Qiang; Li, Shu-Hong; Wang, Wen-Jun

    2015-05-01

    We present a theoretical study of the influence of a single silver sphere on the fluorescence of radix angelica dahurica, which is a kind of traditional Chinese medicine. The enhancement factors of the excitation and the relaxation processes are deduced. The excitation can be enhanced more than 100 times at 315 nm. The enhancement factor of the emission can reach up to 9 at a center wavelength of 400 nm. Project supported by the National Natural Science Foundation of China (Grant Nos. 61405085 and 61275147), the Research Fund for the Doctoral Program of Liaocheng University, China, the Key Project of Science and Technology of Shandong Province of China (Grant No. 2010GGX10127), and the Shandong Province Natural Science Foundation of China (Grant Nos. ZR2013EML006 and ZR2012AL11).

  12. Inhibition of acetylcholinesterase by extracts and constituents from Angelica archangelica and Geranium sylvaticum.

    PubMed

    Sigurdsson, Steinthor; Gudbjarnason, Sigmundur

    2007-01-01

    The aim of this study was to explore the acetylcholinesterase (AChE) inhibition of several Icelandic medicinal herbs. Ethanolic extracts of Angelica archangelica seeds and the aerial parts of Geranium sylvaticum proved effective, with IC50 values of 2.20 mg/ml and 3.56 mg/ml, respectively. The activity of imperatorin and xanthotoxin from A. archangelica was measured. Xanthotoxin proved much more potent than imperatorin, with an IC50 value of 155 microg/ml (0.72 mM) but that for imperatorin was above 274 microg/ml (1.01 mM). However, furanocoumarins seem to have a minor part in the total activity of this extract. Synergistic interaction was observed between the extracts of A. archangelica and G. sylvaticum. Several medicinal herbs (Achillea millefolium, Filipendula ulmaria, Thymus praecox and Matricaria maritima) did not show AChE inhibitory activity. PMID:18069242

  13. Anti-anxiety Activity of Methanolic Extracts of Different Parts of Angelica archangelica Linn.

    PubMed Central

    Kumar, Dinesh; Bhat, Zulfiqar Ali

    2012-01-01

    Angelica archangelica Linn.is a herb distributed in tropical and subtropical regions of the world. In Indian and Chinese system of medicine, it is used for nervous disorders and cerebral diseases. Previously the aqueous extract of the A. archangelica was evaluated for anxiolytic activity and was found to have significant potential for the same. The present study is aimed to evaluate the anxiolytic activity of methanol extract of root (MER), stem (MES), leaf (MEL), fruit (MEF) and whole plant (MEW) of Angelica archangelica Linn. All the extracts (MER, MES, MEL, MEF and MEW) were evaluated for anxiolytic effects using elevated plus maze test (EPM) model in rats. Methanol extracts of different parts of A.archangelica had increased number of entries and time spent in open arms while they decreased the number of entries and duration of time spent in closed arm of the EPM. In a similar fashion, the diazepam increased the percentage of time spent and percentage of arm entries in the open arms (*P <0.05, **P <0.01). Whole plant and the root had the maximum, leaf and fruits showed intermediate, while stem had the least anxiolytic activity (*P <0.05, **P <0.01) in EPM (Figure 1-5). The head dip count in DZ, SMR400, SML400, SMF400 and SMW400 in open arm are significantly shown in Table 1. The DZ, SMF400 and SMW did not show the fecal bolus while other groups were reduced the fecal bolus significantly (**P <0.01) as compared to control (Table 1). Whole plant and leaf showed the most, root and fruit the intermediate and stem the least anxiolytic activity (**P <0.01) in EPM. PMID:24716138

  14. Ethnobotany of dye plants in Dong communities of China

    PubMed Central

    2014-01-01

    Background Dyes derived from plants have an extensive history of use for coloring food and clothing in Dong communities and other indigenous areas in the uplands of China. In addition to use as coloring agents, Dong communities have historically utilized dye plants for their value for enhancing the nutritive, medicinal and preservative properties of foods. However, the persistence of plant-derived dyes and associated cultural practices and traditional knowledge is threatened with rapid socio-economic change in China. Research is needed to document the ethnobotany of dye plants in indigenous communities towards their conservation and potential commercialization as a sustainable means of supporting local development initiatives. Methods Semi-structured surveys on plants used for coloring agents and associated traditional knowledge were conducted in fifteen Dong villages of Tongdao County in Hunan Province of South Central China during 2011–2012. Transect walks were carried out with key informants identified from semi-structured surveys to collect samples and voucher specimens for each documented plant species for taxonomic identification. Results Dong households at the study sites utilize the flowers, bark, stems, tubers and roots of 13 plant species from 9 families as dyes to color their customary clothing and food. Out of the documented plants, a total of 7 are used for coloring food, 3 for coloring clothing and 3 for both food and clothing. Documented plants consist of 3 species that yield black pigments, 3 for brownish red/russet pigments, 3 for red pigments, 2 for dark blue pigments and 2 for yellow pigments. In addition to dyes, the plants have multiple uses including medicinal, ornamental, sacrificial, edible, and for timber. Conclusions The use of dyes derived from plants persists at the study sites for their important role in expressing Dong cultural identity through customary clothing and food. Further research is needed to evaluate the safety of dye plants, their efficacy in enhancing food items and their commercial potential. Conservation policies and management plans are called for to preserve these ethnobotanical resources in a sustainable manner that supports local livelihoods while maintaining cultural practices. PMID:24552267

  15. Bioactivity-guided fractionation for the butyrylcholinesterase inhibitory activity of furanocoumarins from Angelica archangelica L. roots and fruits.

    PubMed

    Wszelaki, Natalia; Paradowska, Katarzyna; Jamróz, Marta K; Granica, Sebastian; Kiss, Anna K

    2011-09-14

    Isolation and identification of the inhibitors of butyrylcholinesterase (BChE), obtained from the extracts of roots and fruits of Angelica archangelica L., are reported. Our results confirmed the weak inhibitory effect of Angelica roots on acetylcholinesterase activity. BChE inhibition was much more pronounced at a concentration of 100 ?g/mL for hexane extracts and attained a higher rate than 50%. The TLC bioautography guided fractionation and spectroscopic analysis led to the isolation and identification of imperatorin from the fruit's hexane extract and of heraclenol-2'-O-angelate from the root's hexane extract. Both compounds showed significant BChE inhibition activity with IC(50) = 14.4 ± 3.2 ?M and IC(50) = 7.5 ± 1.8 ?M, respectively. Only C8-substituted and C5-unsubstituted furanocoumarins were active, which could supply information about the initial structures of specific BChE inhibitors. PMID:21786787

  16. Antioxidant activities of some common ingredients of traditional chinese medicine,Angelica sinensis,Lycium barbarum andPoria cocos

    Microsoft Academic Search

    Sue-Jing Wu; Lean-Teik Ng; Chun-Ching Lin

    2004-01-01

    The antioxidant activities of three popular ingredients of traditional Chinese medicine, namely Angelica sinensis (AS), Lycium barbarum (LB) and Poria cocos (PC) were evaluated in this study. The results showed that aqueous extracts of these crude drugs exhibited antioxidant activities in a concentration-dependent man- ner. All extracts displayed an inhibitory effect on FeCl2-ascorbic acid induced lipid peroxidation in rat liver

  17. Logical Linked Data Compression Amit Krishna Joshi, Pascal Hitzler, and Guozhu Dong

    E-print Network

    Hitzler, Pascal

    Logical Linked Data Compression Amit Krishna Joshi, Pascal Hitzler, and Guozhu Dong Kno.dong}@wright.edu Abstract. Linked data has experienced accelerated growth in recent years. With the continuing proliferation of structured data, demand for RDF compression is becoming increasingly important. In this study, we introduce

  18. [Origin of and analysis on "wind syndrome" in medicine of Dong nationality].

    PubMed

    Liu, Yu-Heng; Ding, Feng; Ding, Jia

    2003-01-01

    As a major component of diseases, "wind syndrome" in medicine of Dong nationality is closely related to the way of thinking, ecological surrounding, and culture of Dong ethnic group. This syndrome is very primitive with very extensive inclusion and ethnic uniqueness. PMID:12921597

  19. Novel characterization of Radix Angelicae Dahuricae before and after the sulfur-fumigation process by combining high performance liquid chromatographic fingerprint and multi-ingredients determination

    PubMed Central

    Liu, Xiao; Liu, Jingjing; Cai, Hao; Li, Songlin; Ma, Xiaoqing; Lou, Yajing; Qin, Kunming; Guan, Hongyue; Cai, Baochang

    2014-01-01

    Background: Harmful sulfur-fumigation processing method is abused during Radix Angelicae Dahuricae preparation. However, the analytical technique characterizing Radix Angelicae Dahuricae before and after the sulfur-fumigation process is absent. Materials and Methods: The high performance liquid chromatography (HPLC) technique was adopted to develop methods combining finger-print analysis and multi-ingredients simultaneous determination for quality evaluation of Radix Angelicae Dahuricae before and after the sulfur-fumigation process. The chromatographic fingerprint method was established for qualitative analysis coupled with statistical cluster analysis basing on Euclidean distance. Additionally, a determination method was developed for quantitative analysis, which was able to assay the concentrations of the major coumarins including imperatorin, isoimperatorin, xanthotoxin, xanthotoxol, isoimpinellin, oxypeucedanin, and bergapten in Radix Angelicae Dahuricae simultaneously. The separations of the two methods were both achieved on a Hypersil octadecylsilyl C18 column (250 mm × 4.6 mm, 5 ?m) at 35°C under different strategic gradient elution programs. The detection wavelength was set at 254 nm all the time. Method validation data indicated that the methods were both reliable and applicable. They were then used to assay different Radix Angelicae Dahuricae samples collected from good agricultural practice (GAP) bases and local herbal markets. Results: The successful application demonstrated that the combination of HPLC fingerprint and simultaneous quantification of multi-ingredients offers an efficient approach for quality evaluation of Radix Angelicae Dahuricae before and after the sulfur-fumigation process. Conclusion: In order to discriminate Radix Angelicae Dahuricae before and after the sulfur-fumigation process, oxypeucedanin, and xanthotoxol were the most sensitive biomarkers and should be determined. PMID:25210323

  20. Antioxidant and ACE Inhibitory Activity of Cultivated and Wild Angelica gigas Nakai Extracts Prepared Using Different Extraction Conditions

    PubMed Central

    Noh, Bo-Young; Lee, Hye-Jin; Do, Jeong-Ryong; Kim, Hyun-Ku

    2014-01-01

    The purpose of this study was to investigate the biological activities of cultivated Angelica gigas Nakai (CAG) and wild Angelica gigas Nakai (WAG) extracts prepared by extraction with water, 30% ethanol, 60% ethanol, or 90% ethanol. The electron donating ability of the WAG extracts was higher than that of the CAG extracts and 0.1% and 1.0% solutions of the comparative substance, L-ascorbic acid. The superoxide dismutase-like activity of the CAG extracts was higher than that of WAG extracts. Superoxide dismutase-like activity was highest (33.95%) in the CAG water extract. The total polyphenol content was highest in the 60% ethanol extracts of WAG. The nitrite scavenging ability of the CAG and WAG extracts was highest at a pH of 1.2. The tyrosinase inhibitory effect was highest (43.72%) in the water extract of WAG. The angiotensin converting enzyme inhibitory activity was highest (83.84%) in the 60% ethanol extract of WAG. The results of the present study will be useful for understanding the antioxidant and angiotensin-converting enzyme inhibitory activities of Angelica gigas Nakai extracts. PMID:25580391

  1. Assessment and comparison of immunoregulatory activity of four hydrosoluble fractions of Angelica sinensisin vitro on the peritoneal macrophages in ICR mice.

    PubMed

    Chen, Ying; Duan, Jin-ao; Qian, Dawei; Guo, Jianming; Song, Bingsheng; Yang, Ming

    2010-04-01

    Angelica sinensis (Oliv) Diels, a traditional oriental herbal medicine, is known to have immunostimulatory and antitumor effects. In this paper, four hydrosoluble fractions were obtained and purified from A. sinensis including: Angelica polysaccharide, oligosaccharides (Angelica oligosaccharide and Angelica sucrose) and Angelica total amino acid, named APS, AOS, AS, and TAA, respectively. Moreover, the immunomodulatory activity of these four fractions on murine peritoneal macrophages were assessed and compared from various aspects including cell proliferation, phagocytic activity, nitric oxide (NO) and hydrogen peroxide (H(2)O(2)) release, induced nitric oxide synthetase (iNOS) and lysozyme (LZM) activity, intracellular adhesion molecule-1 (ICAM-1) expression on cell surface and Toll-like receptor 4 (TLR4) gene expression. Although APS exhibited the most obvious growth facilitative activity, AOS did better in activation of H(2)O(2) release; TAA exerted the best activation of phagocytic activity, production of NO and ICAM-1 expression. Furthermore, we found that the action mode of the four fractions was similar to that of LPS and the mechanism may be related to the upregulation of TLR4 mRNA. These results demonstrated that oligosaccharide and amino acid fractions, as well as polysaccharide fraction of Radix A. sinensis, could serve as immunomodulator and TLR4 as one of the immune receptors may play important role for this action. PMID:20093201

  2. An Experimental Novel Study: Angelica sinensis Prevents Epidural Fibrosis in Laminectomy Rats via Downregulation of Hydroxyproline, IL-6, and TGF-?1

    PubMed Central

    Kong, Xiaohong; Zhao, Xuechao; Zhou, Xianhu; Su, Yanhua; Sharma, Hari S.; Feng, Shiqing

    2013-01-01

    With laminectomy being widely accepted as the treatment for lumbar disorders, epidural fibrosis (EF) is a common complication for both the patients and the surgeons alike. Currently, EF is thought to cause recurrent postoperative pain after laminectomy or after discectomy. Angelica sinensis is a traditional Chinese medicine which has shown anti-inflammatory, antifibrotic, and antiproliferative properties. The object of this study was to investigate the effects of Angelica sinensis on the prevention of post-laminectomy EF formation in a rat model. A controlled double-blinded study was conducted in sixty healthy adult Wistar rats that underwent laminectomy at the L1-L2 levels. They were divided randomly into 3 groups according to the treatment method, with 20 in each group: (1) Angelica sinensis treatment group, (2) saline treatment group, and (3) sham group (laminectomy without treatment). All rats were euthanized humanely 4 weeks after laminectomy. The hydroxyproline content, Rydell score, vimentin cells density, fibroblasts density, inflammatory cells density, and inflammatory factors expressions all suggested better results in Angelica sinensis group than the other two groups. Topical application of Angelica sinensis could inhibit fibroblasts proliferation and TGF-?1 and IL-6 expressions and prevent epidural scar adhesion in postlaminectomy rat model. PMID:24069047

  3. Effects of ferulic acid on antioxidant activity in Angelicae Sinensis Radix, Chuanxiong Rhizoma, and their combination.

    PubMed

    Wang, Lin-Yan; Tang, Yu-Ping; Liu, Xin; Zhu, Min; Tao, Wei-Wei; Li, Wei-Xia; Duan, Jin-Ao

    2015-06-01

    The present study aimed at exploring different roles of the same compound in different environment, using preparative HPLC, and the significance to investigating bio-active constituents in traditional Chinese medicine (TCM) on the basis of holism. In this study, the depletion of target component ferulic acid (FA) by using preparative HPLC followed by antioxidant activity testing was applied to investigate the roles of FA in Angelicae Sinensis Radix (DG), Chuanxiong Rhizoma (CX) and their combination (GX). The antioxidant activity was performed by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity testing. FA was successfully and exclusively depleted from DG, CX, and GX, respectively. By comparing the effects of the samples, it was found that FA was one of the main antioxidant constituents in DG, CX and GX, and the roles of FA were DG > CX > GX. Furthermore, the effects of FA varied at different doses in these herbs. This study provided a reliable and effective approach to clarifying the contribution of same compound in different TCMs to their bio-activities. The role of a constituent in different TCMs might be different, and a component with the same content might have different effects in different chemical environments. Furthermore, this study also suggested the potential utilization of preparative HPLC in the characterization of the roles of multi-ingredients in TCM. PMID:26073335

  4. Inhibitory effect of Angelica sinensis extract in the presence of 2-hydroxypropyl-?-cyclodextrin.

    PubMed

    Hsu, Chin-Mu; Tsai, Fuu-Jen; Tsai, Yuhsin

    2014-12-19

    Angelica sinensis (AS) is a traditional Chinese medicinal herb. Its ethanolic extract contains active ingredients, such as ferulic acid, ligustilide, and butylidenephthalide, which are hydrophobic and have inhibitory effects on hepatoma cells. To increase the aqueous solubility/dispersibility of AS extract and study the consequent inhibitory effect on hepatoma cells, the ethanolic extract of AS was complexed with 2-hydroxypropyl-?-cyclodextrin (HP-?-CD), a cyclic oligosaccharide that has a hydrophilic outer surface and a hydrophobic central cavity. The AS-HP-?-CD complex (weight ratio of AS extract: HP-?-CD=1:5) was prepared and characterized. The effect of complexing the AS extract with HP-?-CD on Hep3B cell growth was investigated by analyzing cytotoxicity. Our results showed that cytotoxicity inhibition of AS-HP-?-CD complex was up to 94% and higher than that of AS extract (about 68%). These observations suggested that the use of HP-?-CD to stabilize AS extract in aqueous solution was possible for herbal medicine application. PMID:25263871

  5. Protection of Angelica sinensis (Oliv) Diels against hepatotoxicity induced by Dioscorea bulbifera L. and its mechanism.

    PubMed

    Niu, Chengwei; Wang, Junming; Ji, Lili; Wang, Zhengtao

    2014-01-01

    Dioscorea bulbifera L., a traditionally used medicinal plant in China, is reported to induce hepatotoxicity. The present study is designed to investigate the protection of an ethanol extract of Angelica sinensis (Oliv) Diels (AE) against an ethyl acetate fraction of D. bulbifera (EF)-induced liver injury and its engaged mechanism. High performance liquid chromatography (HPLC) analysis showed that the amount of diosbulbin B in EF was 16.03% and ferulic acid in AE was 0.18%. EF (350 mg/kg) increased serum alanine/aspartate aminotransferase (ALT/AST), alkaline phosphatase (ALP) activities and total bilirubin (TB) amount, while AE inhibited such an increase. Liver histological evaluation showed that AE prevented development of severe hepatic lesions induced by EF. Further results showed that EF decreased the expression of Bcl-2 and induced the cleaved activation of caspase-9 and -3, and all those effects were reversed by AE. AE also reversed EF-induced decreased expression of the inhibitor of kappa B (I?B), superoxide dismutase (SOD), and glutathione peroxidase (GPx). Taken together, our results demonstrate that AE can prevent EF-induced hepatotoxicity via preventing apoptosis, meanwhile I?B, SOD, and GPx may be involved in such protection. PMID:25382441

  6. [Removal of heavy metals from extract of Angelica sinensis by EDTA-modified chitosan magnetic adsorbent].

    PubMed

    Ren, Yong; Sun, Ming-Hui; Peng, Hong; Huang, Kai-Xun

    2013-11-01

    The concentrations of heavy metals in the extracting solutions of traditional Chinese medicine are usually very low. Furthermore, a vast number of organic components contained in the extracting solutions would be able to coordinate with heavy metals, which might lead to great difficulty in high efficient removal of them from the extracting solutions. This paper was focused on the removal of heavy metals of low concentrations from the extracting solution of Angelica sinensis by applying an EDTA-modified chitosan magnetic adsorbent (EDTA-modified chitosan/SiO2/Fe3O4, abbreviated as EDCMS). The results showed that EDCMS exhibited high efficiency for the removal of heavy metals, such as Cu, Cd and Pb, e.g. the removal percentage of Cd and Pb reached 90% and 94.7%, respectively. Besides, some amounts of other heavy metals like Zn and Mn were also removed by EDCMS. In addition, the total solid contents, the amount of ferulic acid and the HPLC fingerprints of the extracting solution were not changed significantly during the heavy metal removal process. These results indicate that EDCMS may act as an applicable and efficient candidate for the removal of heavy metals from the extracting solution of A. sinensis. PMID:24494559

  7. Angelica sinensis induces hair regrowth via the inhibition of apoptosis signaling.

    PubMed

    Kim, Mi Hye; Choi, You Yeon; Cho, Ik-Hyun; Hong, Jongki; Kim, Sung-Hoon; Yang, Woong Mo

    2014-01-01

    Hair loss is accompanied by keratinocyte apoptosis-regression during catagen and prolonged telogen. Angelica sinensis was reported to promote hair growth in vitro. Based on previous studies, we explored the hair growth effect and the mechanism of A. sinensis related to keratinocyte apoptosis-regression during catagen in mice. The 70% Ethanol extract of A. sinensis was applied topically at doses of 1 and 100 mg/mL to the dorsa of C57BL/6 mice for 2 weeks. The A. sinensis-treated group showed noticeable hair regrowth. Treatment with A. sinensis restored the lengths of hair shafts and size of hair follicles. In addition, mice treated with A. sinensis showed notably decreased apoptotic cells, along with a significant change in the expression of cleaved caspase-3 and the ratio of a pair of apoptosis-associated proteins: Bcl-2 and Bax. Also, A. sinensis inhibited the nuclear translocation of NF-?B, the phosphorylation of I?B-?, the phosphorylation of three mitogen-activated protein MAP kinases, and the activation of c-Jun with decreased TNF-?. These findings reveal a role of A. sinensis as an alternative treatment for hair loss that acts through hair cycle pathways associated with apoptosis regression during catagen. PMID:25004889

  8. Identification of new urinary metabolites of byakangelicin, a component of Angelicae dahuricae Radix, in rats.

    PubMed

    Kwon, Oh-Seung; Song, Yun-Seon; Shin, Kuk-Hyun; Ryu, Jae-Chun

    2003-08-01

    Byakangelicin, 9-(2,3-dihydroxy-2-methylbutoxy)-4-methoxy-7H-furo[3,2-g][l]benzopyran-7-one (BKG), a component of Angelicae dahuricae Radix, is considered to be an inhibitor of aldose reductase for the treatment of diabetic cataract. An analytical method for the isolation of BKG developed by high-performance liquid chromatography has been reported. No literature on the metabolism of BKG, however, has been found. With the purpose of identifying new metabolites of BKG, BKG (100 mg/kg) was orally administered to Sprague-Dawley rats via a gavage. Using a metabolic cage, urine was collected for 24 h, and the urine samples were extracted by liquid-liquid extraction. For structural identification of new urinary metabolites of BKG, various instrumental analyses were conducted by gas-chromatography/mass spectrometry, high-performance liquid chromatography/diode array detector, liquid chromatography/mass spectroscopy with thermospray interface and 1H nuclear magnetic resonance spectroscopy. Two metabolites produced from the O-demethylation or O-dealkylation of BKG were newly identified, and another new but unknown metabolite was assumed to be the hydroxylated form of BKG. These results indicate that the major metabolic products of BKG are formed by O-demethylation or O-dealkylation of BKG side chains. PMID:12967195

  9. An ethanolic extract of Angelica gigas improves atherosclerosis by inhibiting vascular smooth muscle cell proliferation.

    PubMed

    Jang, Ja Young; Kim, Jihyun; Cai, Jingmei; Kim, Youngeun; Shin, Kyungha; Kim, Tae-Su; Lee, Sung-Pyo; Park, Sung Kyeong; Choi, Ehn-Kyoung; Kim, Yun-Bae

    2014-06-01

    The effects of an ethanolic extract of Angelica gigas (EAG) on the vascular smooth muscle cell (VSMC) proliferation and high-cholesterol diet-induced hypercholesterolemia and atherosclerosis were investigated. Rat aortic VSMCs were stimulated with platelet-derived growth factor-BB (25 ng/mL) for the induction of DNA synthesis and cell proliferation. EAG (1-10 µg/mL) significantly inhibited both the thymidine incorporation and cell proliferation in a concentration-dependent manner. Hypercholesterolemia was induced by feeding male New Zealand white rabbits with 0.5% cholesterol in diet for 10 weeks, during which EAG (1% in diet) was given for the final 8 weeks after 2-week induction of hypercholesterolemia. Hypercholesterolemic rabbits exhibited great increases in serum total cholesterol and low-density lipoproteins (LDL) levels, and finally severe atheromatous plaque formation covering 28.4% of the arterial walls. EAG significantly increased high-density lipoproteins (HDL), slightly decreased LDL, and potentially reduced the atheroma area to 16.6%. The results indicate that EAG attenuates atherosclerosis not only by inhibiting VASC proliferation, but also by increasing blood HDL levels. Therefore, it is suggested that EAG could be an alternative or an adjunct therapy for the improvement of hypercholesterolemia and atherosclerosis. PMID:24999363

  10. Chalcones from Angelica keiskei attenuate the inflammatory responses by suppressing nuclear translocation of NF-?B.

    PubMed

    Chang, Hee Ryun; Lee, Hwa Jin; Ryu, Jae-Ha

    2014-12-01

    The ethyl acetate-soluble fraction from the ethanolic extract of Angelica keiskei showed potent inhibitory activity against the production of nitric oxide (NO) in lipopolysaccharide (LPS)-activated RAW 264.7 cells. We identified seven chalcones (1-7) from EtOAc-soluble fractions through the activity-guided separation. Four active principles, identified as 4-hydroxyderrcine (1), xanthoangelol E (2), xanthokeismin A (4), and xanthoangelol B (5), inhibited the production of NO and the expression of proinflammatory cytokines, interleukin (IL)-1? and IL-6, in LPS-activated macrophages. Western blotting and reverse transcription-polymerase chain reaction analysis demonstrated that these chalcones attenuated protein and mRNA levels of inflammatory enzymes such as inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Moreover, these active compounds suppressed the degradation of inhibitory-?B? (I-?B?) and the translocation of nuclear factor ?B (NF-?B) into nuclei of LPS-activated macrophages. These data demonstrate that four chalcones (1, 2, 4, and 5) from A. keiskei can suppress the LPS-induced production of NO and the expression of iNOS/COX-2 genes by inhibiting the degradation of I-?B? and nuclear translocation of NF-?B. Taken together, four chalcones from A. keiskei may have efficacy as anti-inflammatory agents. PMID:25369132

  11. Antifungal activity of the essential oil of Angelica major against Candida, Cryptococcus, Aspergillus and dermatophyte species.

    PubMed

    Cavaleiro, Carlos; Salgueiro, Lígia; Gonçalves, Maria-José; Hrimpeng, Karnjana; Pinto, Jéssica; Pinto, Eugénia

    2015-04-01

    The composition and antifungal activity of the essential oil (EO) of Angelica major and its main components ?-pinene and cis-?-ocimene against clinically relevant yeasts and moulds were evaluated. EO from the plant's aerial parts was obtained by hydrodistillation and analysed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). The oil showed high contents of ?-pinene (21.8 %) and cis-?-ocimene (30.4 %). Minimum inhibitory concentrations (MICs) were measured according to the broth macrodilution protocols by the Clinical and Laboratory Standards Institute (CLSI). The EO, ?-pinene and cis-?-ocimene displayed low MICs and minimum fungicidal concentrations (MFCs) against dermatophytes and Cryptococcus neoformans, with ?-pinene being the most active. Regarding Candida species, the EO susceptibility profiles seem to be diverse and not correlated with fluconazole susceptibility patterns. Moreover, an inhibition of yeast-mycelium transition was demonstrated at sub-inhibitory concentrations of the EO, ?-pinene and cis-?-ocimene in C. albicans. In addition, their haemolytic activity was low. The activity displayed by A. major EO and its main components associated with low cytotoxic activity confirms their potential as an antifungal agent against fungal species frequently implicated in human mycoses, particularly cryptococcosis and dermatophytosis. The association with commercial antifungal compounds could bring benefits, by the effect on germ tube formation, and be used in mucocutaneous candidiasis treatment. PMID:25576097

  12. Polysaccharide Isolated from Angelica sinensis Inhibits Hepcidin Expression in Rats with Iron Deficiency Anemia

    PubMed Central

    Liu, Jin-Yu; Zhang, Yu; You, Ru-Xu; Zeng, Fang; Guo, Dan

    2012-01-01

    Abstract A novel polysaccharide named Angelica sinensis polysaccharide (ASP) was obtained from the powdered and defatted roots of A. sinensis (Oliv.) Diels. The molecular weight of ASP was determined to be 78?kDa and was 95.0% sugars consisting of mostly arabinose, glucose, and galactose with a molar ratio of 1:5.68:3.91. A previous study indicated that ASP may increase plasma iron levels by suppressing the expression of hepcidin, a negative regulator of body iron metabolism, in the liver. The present study aims to clarify the inhibitory effect of ASP on hepcidin expression in rat models of iron deficiency anemia (IDA), and clarify the mechanisms involved. It was demonstrated that ASP significantly reduced hepcidin expression by inhibiting the expression of mothers against decapentaplegic protein 4 (SMAD4) in liver and stimulating the secretion of erythropoietin, which further downregulated hepcidin by repressing CCAAT/enhancer-binding protein ? (C/EBP?) and the phosphorylation of signal transducer and activator of transcription 3/5. The results indicate that ASP can suppress the expression of hepcidin in rats with IDA, and may be useful for the treatment of IDA. PMID:22985399

  13. Chemical composition and antioxidant activities of different polysaccharides from the roots of Angelica dahurica.

    PubMed

    Xu, Shi-Fang; Ye, Yi-Ping; Li, Xiao-Yu; Chen, Feng-Yang

    2011-06-01

    The total crude polysaccharides (CADPs), isolated from the roots of Angelica dahurica by H(2) O extraction, EtOH precipitation, and dialysis, and the four fractions ADP1, ADP2, ADP3, and ADP4, obtained by gel filtration of the CADPs, were analyzed to characterize their composition and evaluated for their antioxidant activity using different in vitro tests such as the malondialdehyde (MDA)-production, the ferrous ion (Fe(2+) )-chelating, and the HO(.) radical-scavenging assays. The predominant neutral monosaccharides in the four fractions were identified as arabinose, galactose, and glucose, while the composition and ratio of the monosaccharides were different between the fractions. The CADPs and its fractions were found to significantly inhibit lipid peroxidation, chelate Fe(2+) , and scavenge HO(.) radicals, indicating that these polysaccharides possessed antioxidant activity. Among the four fractions, ADP4 exhibited the strongest antioxidant activity, which was stronger than that of the control antioxidant vitamin E (Vit E). Taken together, the chemical composition of these polysaccharides might affect their antioxidant activity, and ADP4 could be explored as a source of potential novel natural antioxidants for food and pharmaceutical purposes. PMID:21674784

  14. [Chemical constituents of Aconitum brachypodum from Dong-Chuan area].

    PubMed

    Wang, Hong-Yun; Zuo, Ai-Xue; Sun, Yun; Rao, Gao-Xiong

    2013-12-01

    Aconitum brachypodum is traditionally known to be toxic chinese medicie, but its chemical constituents is not enough studied to date. To further elucidate the chemical constituents of A. brachypodum, 80% ethanol extract of A. brachypodum collected from Dong-Chuan area was investigated, which led to isolation of seventeen compounds. By spectroscopic methods, their structures were determined as hypaconitine (1), mesaconitine (2), talatisamine (3), neoline (4), fuziline (5), aconine (6), bullatine A (7), lepeine (8), songrine (9), isocorydine (10), beta-sitosterol (11), daucosterol (12), stearic acid (13), triacontanol (14), palmitic acid (15), benzoic acid (16), and inosine (17), respectively. All compounds except for compounds 1 and 7 were isolated from A. brachypodum for the first time. PMID:24791539

  15. [Determination of sarsasapogenin in "tian dong" by TLCS].

    PubMed

    Yu, B; Luo, X; Xu, Y; Xu, L; Xu, G

    2001-08-01

    This paper reported the determination of sarsasapogenin in 12 samples from 7 species and varieties of Asparagus genus whose commercial name is "Tian-Dong"(Radix Asparagi), Asparagus cochichinensis(Lour.) Merr, A. cochichinensis (lour.) Merr. var. gaudichaudianus (Kunth) X. D. Luo and G. J. Xu, A. taliensis Wang et Tang, A. munitus Wang et Tang, A. myriacanthus Wang et S. C. Chen, A. meioclados Levl and A. trichoclados (Wang et Tang) Wang et S. C. Chen by TLCS. The results showed that it was no pertinence between content of sarsaspogenin with the species, and the content of sarsasapogenin in the tuberous roots was inverse ratio with the commercial grande in same species. PMID:11715195

  16. Multiple environmental signals required for embryo growth and germination of seeds of Selinum carvifolia (L.) L. and Angelica sylvestris L. (Apiaceae)

    Microsoft Academic Search

    Filip Vandelook; Nele Bolle; Jozef A. Van Assche

    2007-01-01

    Germination and dormancy breaking requirements were studied in Selinum carvifolia (L.) L. and Angelica sylvestris L. (Apiaceae). Seeds of these two species have an underdeveloped embryo and are morpho- physiologically dormant. The embryo does not start to grow until physiological dormancy is broken by cold stratification. Incubating seeds at fluctuating temperatures in the light, after cold stratification, had a stimulating

  17. NUMERICAL SIMULATIONS OF AIR FLOW AND HEAT TRANSFER VIA PDES Fei Cao, Luz Angelica Caudillo-Mata, Natalia Iwanski, Yong Li, Kamran Sadiq,

    E-print Network

    NUMERICAL SIMULATIONS OF AIR FLOW AND HEAT TRANSFER VIA PDES By Fei Cao, Luz Angelica Caudillo://www.ima.umn.edu #12;IMA Mathematical Modeling in Industry XVII Workshop: Numerical Simulations of Air Flow and Heat of a simplified PDE model for simulating air flow and heat transfer, with the aim of gaining experience

  18. [Chemo-preventive effect of Angelica sinensis' supercritical extracts on AOM/DSS-induced mouse colorectal carcinoma associated with inflammation].

    PubMed

    An, Jing; Li, Xiao-Ning; Zhao, Bo-Chen; Wang, Qiong; Lan, Yi; Wu, Qing

    2014-04-01

    To study the chemo-preventive effect of the supercritical extracts from Angelica sinensis (SFE-AS) on induced colorectal carcinoma in mice by using the AOM/DSS-induced male mice colorectal carcinoma model, and discuss its possible action mechanism. Male Balb/c mice were subcutaneously injected with single dose of azoxymethane (AOM, 10 mg x kg(-1) body weight). One week later, they were given 2% dextran sodium sulfate (DSS) in drinking water for 7 days to induce colorectal carcinoma. Each drug group was orally administered with supercritical extracts from Angelica sinensis at 15, 30, 60 mg x kg(-1) until the 17th week. The tumor incidence rate of the SFE-AS group, mice tumor-bearing quantity and tumor-bearing volume of the SFE-AS group were lower than that of the AOM/DSS model control group, which may be related with the significant reduction of PCNA, COX-2, iNOS in the AOM/DSS-induced mouse colorectal carcinoma model associated with inflammation by SFE-AS. According to the results of this study, SFE-AS showed an intervention effect in the incidence and development of AOM/DSS-induced mouse colorectal carcinoma associated with inflammation, and could be further used in chemo-preventive studies on human colorectal carcinoma. PMID:25011266

  19. [Comparative metabonomics study on urine in rat treated by Angelica sinensis volatile oil].

    PubMed

    Li, Jin-Xia; Zhang, Man; Sun, Li-Bo; Zhang, Ling; Zhang, Wen-Quan; Zhao, Hai-Fu; Li, Peng-Ling; Hua, Yong-Li; Ji, Peng; Wei, Yan-Ming

    2014-04-01

    Metabonomics was employed to investigate the effect of Angelica sinensis volatile oil (ASVO) to the endogenous metabolites of normal rats, and to reveal the possible ways of metabolism in rats caused by ASVO. The fifty male Waster rats were randomly divided into five groups (each consists of 10 rats), such as control group, high dose group of ASVO, middle dose group of ASVO, low dose group of ASVO, and Aspirin group. They were given 0.9% saline, 0.352 mL x kg(-1) ASVO, 0.176 mL x kg(-1) ASVO, 0.088 mL x kg(-1) ASVO and ASP respectively with the equal volume of 0.2 mL. Drugs and vehicle were given for 3 successive days. The urine was collected at 12, 24, 36, 48 h after modeling with metabolic cages. Rat urine metabolic fingerprint in different stages was analyzed using GC-MS, based on which the principal component analysis (PCA)and orthogonal partial least-squares discriminant analysis (OPLS-DA) models were established for metabonomic analysis. Potential biomarkers were screened by using variable importance in the projection (VIP) and T test. It was revealed that the middle dose of ASVO at 36 h induces a substantial change in rat urine. Compared with control group, seven kinds of endogenous metabolites in ASP group and ASVO group change significantly (P < 0.05), among which aconitic acid, succinic acid, citric acid, alpha-ketone glutaric acid, glycine and malic acid content had an upward trend (P < 0.05) and prostaglandin content had a downward trend (P < 0.01). The mechanism of ASVO and ASP have the similarity. It is likely that ASVO intervenes the metabolic process by affecting the energy, amino acid and lipid metabolism. Our work also indicates that rats administrated with ASVO can increase the energy metabolism of the body, induce the production of inflammatory substances and strengthen the body's immune ability. The result has also provide a proof for futher interpret ASVO pharmacological effects. PMID:25011271

  20. Regional water quality management for the Dong Nai River Basin, Vietnam.

    PubMed

    Grayman, W M; Day, H J; Luken, R

    2003-01-01

    A three-year study that started solely as an industrial pollution reduction effort in Dong Nai Province of Vietnam expanded into an ongoing regional river basin water quality management effort. The project was a cooperative effort between the United Nations (UNDP and UNIDO) and the Federal and Provincial governments in Vietnam. A comprehensive approach was used to assess the impacts and strategies for reducing industrial, municipal and agricultural pollution to the water, air and land. The strategy was based upon use of knowledge in four subject areas, economics, ecology, technology and institutions, integrated within a framework for regional environmental quality management, sometimes called Areawide Environmental Quality Management (AEQM). Dong Nal Province encompasses a major developing area immediately north of Ho Chi Minh City. The land area chosen for the AEQM study is the 1,400 square kilometre region in and around Bien Hoa that drains into the Dong Nai River. The Dong Nai River serves many purposes including navigation, fisheries and a water supply for both the Province and Ho Chi Minh City. Extensive industrial and residential development was underway and was projected to increase in the coming decade. A strategy for the control of pollution from liquid, gaseous and solid wastes for the period 1998 to 2010 in Dong Nai Province was developed. PMID:15137148

  1. Simultaneous determination of ferulic acid and phthalides of Angelica sinensis based on UPLC-Q-TOF/MS.

    PubMed

    Wei, Wen-Long; Huang, Lin-Fang

    2015-01-01

    The radix of Angelica sinensis (AS) is one of the most commonly used as a herbal medicine. To investigate the geoherbalism and quality evaluation of AS, an ultra performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry (UPLC-ESI-Q-TOF/MS) method was established to analyze and identify ferulic acid and phthalides in AS. The results showed that among samples collected in four regions, the relative contents of ferulic acid and phthalides were highest in samples collected in Gansu, and the samples from the four different regions were apparently classified into four groups. Meanwhile, the relative content in non-fumigated root was higher than after sulfur-fumigation and the sulfur-fumigated and non-fumigated samples were obviously divided into two groups by PCA. The paper establishes a systematic and objective evaluation system to provide a scientific basis for evaluating the quality of AS. PMID:25781070

  2. A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway

    Microsoft Academic Search

    W. Cao; X.-Q. Li; X. Wang; H.-T. Fan; X.-N. Zhang; Y. Hou; S.-B. Liu; Q.-B. Mei

    2010-01-01

    A novel polysaccharide isolated from Angelica sinensis, named APS-1d showed cytotoxic activity towards several cancer cell lines in vitro. However, the precise antitumor mechanisms of this compound are unknown. In this study, we investigated the pro-apoptotic effects of APS-1d in human cervical cancer HeLa cells both in vitro and in vivo, and further elucidated the mechanisms of this action. Inhibition

  3. Anthelmintic activity of the crude extracts, fractions, and osthole from Radix angelicae pubescentis against Dactylogyrus intermedius in goldfish ( Carassius auratus ) in vivo

    Microsoft Academic Search

    Kai-yu Wang; Lu Yao; Yong-hua Du; Jia-bing Xie; Jin-lu Huang; Zhong-qiong Yin

    2011-01-01

    A bioassay-guided fractionation was performed to evaluate the anthelmintic activity of the crude extract fractions and osthole\\u000a from Radix angelicae pubescentis against Dactylogyrus intermedius in goldfish (Carassius auratus) in vivo. Among four extracts (petroleum ether, ethyl acetate, acetone, and ethanol), only ethanol extract exhibited the\\u000a best anthelmintic efficacy with 100% mortality of Dactylogyrus and no death of fish at the

  4. An Improved LC-MS/MS Method for Simultaneous Determination of the Eleven Bioactive Constituents for Quality Control of Radix Angelicae Pubescentis and Its Related Preparations

    PubMed Central

    Li, Jin; Zhang, Qiu-Hong; He, Jun; Liu, Er-wei; Gao, Xiu-mei; Chang, Yan-xu

    2015-01-01

    An improved LC-MS/MS method was developed for simultaneous determination of eleven bioactive constituents of Radix Angelicae Pubescentis and its related preparations. It was the first report on the quantification of bioactive constituents in different preparations of Radix Angelicae Pubescentis by LC-MS/MS analytical method. These samples were separated with an Agilent Zorbax Extend reversed-phase C18 column (1.8??m, 4.6 × 100?mm) by linear gradient elution using aqueous ammonium acetate and acetonitrile as mobile phase. The flow rate was 0.3?mL?min?1. The eleven bioactive constituents showed good regression (R > 0.990) within test ranges and the recoveries were in the range of 87.1–110%. The limit of detections and quantifications for most of the major constituents were less than 0.5 and 1.0?ng?mL?1, respectively. All results indicated that the developed method could be readily utilized as a suitable quality control method for Radix Angelicae Pubescentis and related preparations.

  5. 0 MINIMIZATION FOR WAVELET FRAME BASED IMAGE RESTORATION YONG ZHANG, BIN DONG, AND ZHAOSONG LU

    E-print Network

    Lu, Zhaosong

    0 MINIMIZATION FOR WAVELET FRAME BASED IMAGE RESTORATION YONG ZHANG, BIN DONG, AND ZHAOSONG LU of image processing and analysis. Image restoration, including image denoising, deblurring, inpainting. Many of the current PDE based methods for image denoising and decomposition utilize TV regularization

  6. Chameleon: Color Transformation on OLED Displays Mian Dong, and Lin Zhong

    E-print Network

    Zhong, Lin

    . Then the software generates a series of transition color schemes between the original and the transformed oneChameleon: Color Transformation on OLED Displays Mian Dong, and Lin Zhong Department of Electrical consumption is an important design concern for mobile systems. Displays have been known as one of the major

  7. Students' difficulties with integration in electricity Dong-Hai Nguyen and N. Sanjay Rebello

    E-print Network

    Zollman, Dean

    Students' difficulties with integration in electricity Dong-Hai Nguyen and N. Sanjay Rebello; published 28 June 2011) This study investigates the common difficulties that students in introductory teaching-learning interviews with 15 students in a second-semester calculus-based introductory physics

  8. FMCW Radar with enhanced frequency estimation# Dong-hun Shin 1

    E-print Network

    Park, Seong-Ook

    FMCW Radar with enhanced frequency estimation# Dong-hun Shin 1 , Seong-Ook Park 2 1 Department radar with enhanced frequency estimation. It has 600MHz bandwidth with 160us sweep time. Distance error system is classified according to source type. Ultra sound radar and microwave radar are used in spread

  9. Z Approach to Semantic Web Jin Song Dong, Jing Sun, and Hai Wang

    E-print Network

    Dong, Jin Song

    Z Approach to Semantic Web Jin Song Dong, Jing Sun, and Hai Wang School of Computing, National University of Singapore, {dongjs,sunjing,wangh}@comp.nus.edu.sg Abstract. The Semantic Web (SW) service contribute to the Semantic Web-based system de- velopment in many ways. In this paper, we firstly conduct

  10. Berry-Esseen bounds for the number of maxima in planar regions ZHI-DONG BAI

    E-print Network

    Tsai, Tsung-Hsi

    Berry-Esseen bounds for the number of maxima in planar regions ZHI-DONG BAI Department mean and variance); see Bai et al. (2001) for more precise results. We propose new tools for dealing with the n-class (see Bai et al. (2001)) in this paper. Such a dominance relation among points is a natural

  11. Towards Logical Linked Data Compression Amit Krishna Joshi, Pascal Hitzler, and Guozhu Dong

    E-print Network

    Hitzler, Pascal

    Towards Logical Linked Data Compression Amit Krishna Joshi, Pascal Hitzler, and Guozhu Dong Kno.e.sis Center, Wright State University, Dayton, OH, U.S.A. Abstract. Linked data has experienced accelerated growth in recent years. With the continuing proliferation of structured data, demand for RDF compression

  12. Network Intrusion Simulation Using OPNET Shabana Razak, Mian Zhou, Sheau-Dong Lang*

    E-print Network

    Lang, Sheau-Dong

    1 Network Intrusion Simulation Using OPNET Shabana Razak, Mian Zhou, Sheau-Dong Lang* School Florida, Orlando, FL 32816 E-mail: {srazak, mzhou, lang}@cs.ucf.edu Abstract Network intrusion detection to cause disruption of normal system operations, but on the defense, the firewalls and practical intrusion

  13. A DPA Attack on the Improved Ha-Moon Dong Jin PARK and Pil Joong LEE

    E-print Network

    , Chen, Moon and Ha improved the algorithm by removing these drawbacks [7]. Their new algorithm to MSB (i.e. right-to-left). Recently, Yen, Chen, Moon and Ha improved these drawbacks of the Ha- MoonA DPA Attack on the Improved Ha-Moon Algorithm Dong Jin PARK and Pil Joong LEE Information Security

  14. Time-resolved FRET reveals the structural mechanism of SERCAPLB Xiaoqiong Dong a

    E-print Network

    Thomas, David D.

    Time-resolved FRET reveals the structural mechanism of SERCA­PLB regulation Xiaoqiong Dong May 2014 Keywords: Phospholamban SERCA Phosphorylation FRET a b s t r a c t We have used time-resolved fluorescence resonance energy transfer (TR-FRET) to characterize the inter- action between phospholamban (PLB

  15. Scanning Tunneling Potentiometry of Semiconductor Junctions Yang Dong and R. M. Feenstra

    E-print Network

    Feenstra, Randall

    in a semiconductor heterojunction. A demonstration of the method is provided by measurements across GaAs pn1 Scanning Tunneling Potentiometry of Semiconductor Junctions Yang Dong and R. M. Feenstra Dept potentiometry of semiconductor heterojunctions is described. The method yields a direct measure

  16. The RCS of Wire-type Scattering Structures Dong-wook Seo1

    E-print Network

    Myung, Noh-Hoon

    The RCS of Wire-type Scattering Structures Dong-wook Seo1 and Noh-Hoon Myung1 1 School works mainly utilized the method of moment (MoM) for predicting the radar cross section (RCS) of a large to minimize the calculation time. In this case, the total RCS of many wires is simply the product

  17. Computing 2D Periodic Centroidal Voronoi Tessellation Dong-Ming Yan

    E-print Network

    Lévy, Bruno

    Computing 2D Periodic Centroidal Voronoi Tessellation Dong-Ming Yan Project ALICE, INRIA Nancy to compute the centroidal Voronoi tessellation in 2D periodic space. We first present a simple algorithm for constructing the periodic Voronoi diagram (PVD) from a Euclidean Voronoi diagram. The presented PVD algorithm

  18. New Trajectory Generation Methods for Nonholonomic Mobile Robots Wenjie Dong and Yi Guo

    E-print Network

    Guo, Yi

    is the ra- dius of rear driving wheel; u1 is the angular velocity ofthe driving wheels, and u2 is the steeNew Trajectory Generation Methods for Nonholonomic Mobile Robots Wenjie Dong and Yi Guo Department- holonomic mobile robots. We propose two trajectory gen- eration algorithms, one uses a differential flatness

  19. EE406 Intro to Comp. and Net Security Instructor: Yingfei Dong

    E-print Network

    Dong, Yingfei

    Page 1 1 EE406 Intro to Comp. and Net Security 2 · Instructor: Yingfei Dong ­ Research: computer networks and security · Office: H442, 6-3448, MY_FIRST_NAME (AT)hawaii.edu ­ PLEASE put "EE406 Computer Security Technology and Principles ­ cryptography concepts » symmetric and public-key encryption

  20. Folktale Classification using Learning to Rank Dong Nguyen, Dolf Trieschnigg, and Mariet Theune

    E-print Network

    Vellekoop, Michel

    Folktale Classification using Learning to Rank Dong Nguyen, Dolf Trieschnigg, and Mari¨et Theune.nguyen,d.trieschnigg,m.theune}@utwente.nl} Abstract. We present a learning to rank approach to classify folktales, such as fairy tales and urban. In particular, we cast this as a ranking problem, where the goal is to assign the highest rank to the most

  1. On the Dimension of the Space of Magic Squares Over Xiang-dong Houa

    E-print Network

    Sellers, James A.

    On the Dimension of the Space of Magic Squares Over a Field Xiang-dong Houa , Ana G. Lecuonab,1, University Park, PA 16802, USA Abstract We study various spaces of magic squares over a field, and determine their dimensions. These results generalize the main result of Small from 1988. Keywords: latin squares, magic

  2. Reconfigurable Circuit Design with Nanomaterials Chen Dong, Scott Chilstedt, Deming Chen

    E-print Network

    Chen, Deming

    Reconfigurable Circuit Design with Nanomaterials Chen Dong, Scott Chilstedt, Deming Chen Department properties of nanomaterials, such systems are likely to deviate considerably from their predecessors changes without expensive re- masking. In recent years, a wide range of nanomaterials have been introduced

  3. Jampots: a Mashup System towards an E-Learning Ecosystem Bo Dong1, 2

    E-print Network

    Li, Haifei

    such as openness, reusability, lightweight structure, end user-orientation and self-regulation. Keywords-Web2Jampots: a Mashup System towards an E-Learning Ecosystem Bo Dong1, 2 , Qinghua Zheng1, 2 , Lingzhi@gmail.com Abstract--Although E-Learning has grown into a revolutionary way of learning and is currently widely

  4. Design of X-Band FMCW Short Range Radar Dong-hun Shin*

    E-print Network

    Park, Seong-Ook

    Design of X-Band FMCW Short Range Radar Dong-hun Shin* Dept. of Electrical Engineering KAIST Daejeon, Korea husido@kaist.ac.kr Seong-ook Park Dept. of Electrical Engineering KAIST Daejeon, Korea sopark@ee.kaist.ac.kr Abstract-- This paper researches on a X-band FMCW short range radar. It has 160us

  5. PSEUDO-SPLINES, WAVELETS AND FRAMELETS BIN DONG AND ZUOWEI SHEN

    E-print Network

    Shen, Zuowei

    PSEUDO-SPLINES, WAVELETS AND FRAMELETS BIN DONG AND ZUOWEI SHEN Abstract. The first type of pseudo the unitary extension principle of [22]. In the spirit of the first type of pseudo-splines, we introduce here a new type (the second type) of pseudo-splines to construct symmetric or antisymmetric tight framelets

  6. [Effect of combined administration of Angelica polysaccharide and cytarabine on liver of human leukemia NOD/SCID mouse model].

    PubMed

    Zhu, Jia-Hong; Xu, Chun-Yan; Mu, Xin-Yi; Liu, Jun; Zhang, Meng-Si; Jia, Dao-Yong; Zhang, Yan-Yan; Huang, Guo-Ning; Wang, Ya-Ping

    2014-01-01

    Leukemia is a type of malignant tumors of hematopoietic system with the abnormal increased immature leukemia cells showing metastasis and invasion ability. Liver is one of the main targets of the leukemia cells spread to, where they may continue to proliferate and differentiate and cause liver function damage, even liver failure. Our previous studies showed that Angelica polysscharides (APS), the main effective components in Angelica sinensis of Chinese traditional medicine, was able to inhibit the proliferation and induced differentiation of the leukemia cells, however, its effect on the liver during the treatment remains elucidated. In the present study, the human leukemia NOD/SCID mouse model were established by implantation human leukemia K562 cells line, then the leukemia mouse were treated with APS, Ara-c or APS + Ara-c respectively by peritoneal injection for 14 days, to explore the effect and mechanism of the chemicals on the mouse liver. Compared to the human leukemia NOD/SCID mouse model group with the treatments of APS, Ara-c and APS + Ara-c, We found that severe liver damage and pathological changes of the liver were able to alleviate: First, the number of white blood cells in the peripheral blood was significantly lower and with less transplanted K562 leukemia cells; Second, liver function damage was alleviated as liver function tests showed that alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBiL) were significantly reduced, while the albumin (Alb) was notably increased; Third, liver antioxidant ability was improved as the activities of the antioxidant enzymes glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were significantly increased, and the contents of GSH and malonaldehyde (MDA) were decreased significantly in the liver; Fourth, the inflammation of the liver was relieved as the level of IL-1beta and IL-6, the inflammatory cytokines, were decreased significantly in the liver. Fifth, liver index was increased as the pathological observation showed that leukemia cells with diffused infiltration into the liver lobules were significantly reduced and with a remarkable increase of apoptotic positive cell rate by TUNEL test. Furthermore, the APS + Ara-c combined administration showed an even more significant positive effect. In conclusion, the APS, Ara-c therapy reduced the accumulation of leukemia cells within the liver, reduced the liver function damage and levels of inflammatory factors, improved antioxidant capacity of the liver tissue and thus alleviate the pathological changes of the liver. Moreover, the APS + Ara-c combination therapy may have an additive effect. PMID:24754180

  7. [The sequence polymorphism of Y-chromosome DNA and mtDNA of Dong Ethnic of Congjiang, Guizhou].

    PubMed

    Qi, Xiao-Lan; Xie, Yuan; Shan, Ke-Ren; Chu, Xun; Liu, Xuan; Li, Yi; Zhao, Yan; Wu, Chang-Xue; Ma, Jiao; Xiu, Jin; Ren, Xi-Lin

    2005-01-01

    To study the patrilineal and matrilineal genetic structure and the origin of Dong Ethnic of Congjiang Guizhou. Study the distribution of Y-chromosome haplotypes which consisted of 10 SNPs of Y-DNA and mtDNA haplogroups consisted of 11 SNPs by using PCR-RFLP method. The result is three haplotypes H6,H11,H14 were detected, the frequency of H11 is 92.5%. Six haplogroups were identified by mtDNA analysis, 75% of the people can be identified. The patrilineal genetic structure of Dong of Guizhou is simple, Principle component indicated that the structure is closer to Zhuang-Dong branch of Sino-Tibetan language family. The matrilineal genetic structure of Dong of Guizhou is complicated. PMID:15730955

  8. Anti-osteoporotic effects of Angelica sinensis (Oliv.) Diels extract on ovariectomized rats and its oral toxicity in rats.

    PubMed

    Lim, Dong Wook; Kim, Yun Tai

    2014-10-01

    Angelica sinensis root is one of the herbs most commonly used in China; it is also often included in dietary supplements for menopause in Europe and North America. In the present study, we examined the anti-osteoporotic effects of A. sinensis extract in an ovariectomized (OVX) rat model of osteoporosis as well as toxicity of the extract after repeated oral administration. The OVX rats were treated with 17?-estradiol (10 ?g/kg i.p. once daily) or A. sinensis extract (30, 100, and 300 mg/kg, p.o. once daily) for four weeks. The bone (femur) mineral density (BMD) of rats treated with the extract (300 mg/kg) was significantly higher than that of the OVX-control, reaching BMD of the estradiol group. Markers of bone turnover in osteoporosis, serum alkaline phosphatase, collagen type I C-telopeptide and osteocalcin, were significantly decreased in the extract group. The body and uterus weight and serum estradiol concentration were not affected, and no treatment-related toxicity was observed during extract administration in rats. The results obtained indicate that A. sinensis extract can prevent the OVX-induced bone loss in rats via estrogen-independent mechanism. PMID:25325255

  9. A Rapid Discrimination of Authentic and Unauthentic Radix Angelicae Sinensis Growth Regions by Electronic Nose Coupled with Multivariate Statistical Analyses

    PubMed Central

    Liu, Jie; Wang, Weixin; Yang, Yaojun; Yan, Yuning; Wang, Wenyi; Wu, Haozhong; Ren, Zihe

    2014-01-01

    Radix Angelicae Sinensis, known as Danggui in China, is an effective and wide applied material in Traditional Chinese Medicine (TCM) and it is used in more than 80 composite formulae. Danggui from Minxian County, Gansu Province is the best in quality. To rapidly and nondestructively discriminate Danggui from the authentic region of origin from that from an unauthentic region, an electronic nose coupled with multivariate statistical analyses was developed. Two different feature extraction methods were used to ensure the authentic region and unauthentic region of Danggui origin could be discriminated. One feature extraction method is to capture the average value of the maximum response of the electronic nose sensors (feature extraction method 1). The other one is to combine the maximum response of the sensors with their inter-ratios (feature extraction method 2). Multivariate statistical analyses, including principal component analysis (PCA), soft independent modeling of class analogy (SIMCA), and hierarchical clustering analysis (HCA) were employed. Nineteen samples were analyzed by PCA, SIMCA and HCA. Then the remaining samples (GZM1, SH) were projected onto the SIMCA model to validate the models. The results indicated that, in the use of feature extraction method 2, Danggui from Yunnan Province and Danggui from Gansu Province could be successfully discriminated using the electronic nose coupled with PCA, SIMCA and HCA, which suggested that the electronic-nose system could be used as a simple and rapid technique for the discrimination of Danggui between authentic and unauthentic region of origin. PMID:25350503

  10. Anti-Osteoporotic Effects of Angelica sinensis (Oliv.) Diels Extract on Ovariectomized Rats and Its Oral Toxicity in Rats

    PubMed Central

    Lim, Dong Wook; Kim, Yun Tai

    2014-01-01

    Angelica sinensis root is one of the herbs most commonly used in China; it is also often included in dietary supplements for menopause in Europe and North America. In the present study, we examined the anti-osteoporotic effects of A. sinensis extract in an ovariectomized (OVX) rat model of osteoporosis as well as toxicity of the extract after repeated oral administration. The OVX rats were treated with 17?-estradiol (10 ?g/kg i.p. once daily) or A. sinensis extract (30, 100, and 300 mg/kg, p.o. once daily) for four weeks. The bone (femur) mineral density (BMD) of rats treated with the extract (300 mg/kg) was significantly higher than that of the OVX-control, reaching BMD of the estradiol group. Markers of bone turnover in osteoporosis, serum alkaline phosphatase, collagen type I C-telopeptide and osteocalcin, were significantly decreased in the extract group. The body and uterus weight and serum estradiol concentration were not affected, and no treatment-related toxicity was observed during extract administration in rats. The results obtained indicate that A. sinensis extract can prevent the OVX-induced bone loss in rats via estrogen-independent mechanism. PMID:25325255

  11. Metabonomic analysis of the anti-inflammatory effects of volatile oils of Angelica sinensis on rat model of acute inflammation.

    PubMed

    Zhang, Wen-Quan; Hua, Yong-Li; Zhang, Man; Ji, Peng; Li, Jin-Xia; Zhang, Ling; Li, Peng-Ling; Wei, Yan-Ming

    2015-06-01

    Metabonomics based on GC-MS was used to study the possible anti-inflammatory mechanisms of volatile oils of Angelica sinensis (VOAS) in rats with acute inflammation. Acute inflammation was induced by subcutaneous injection of carrageenan in rats. The levels of prostaglandin E2 (PGE2 ), histamine (HIS) and 5-hydroxytryptamine (5-HT) in the inflammatory fluid were detected. Principal component analysis and orthogonal partial least squares-discriminant analysis models were performed for pattern recognition analysis. After the administration of VOAS, the levels of PGE2 , HIS, and 5-HT returned to levels observed in normal group. According to GC-MS analysis, the intervention of VOAS in rats with acute inflammation induced substantial and characteristic changes in their metabolic profiles. Fourteen metabolite biomarkers, namely, lactic acid, malic acid, citric acid, trans-dehydroandrosterone, aldosterone, linoleic acid, hexadecanoic acid, pregnenolone, octadecenoic acid, myristic acid, l-histidine, octadecanoic acid, arachidonic acid (AA) and l-tryptophan, were detected in the inflammatory fluid. The levels of all biomarkers either increased or decreased significantly in model groups. VOAS possibly intervened in the metabolic process of inflammation by altering histidine metabolism, tryptophan metabolism, AA metabolism, steroid hormone biosynthesis, fatty acid metabolism and energy metabolism. Metabonomics was used to reflect an organism's physiological and metabolic state comprehensively, and it is a potentially powerful tool that reveals the anti-acute-inflammatory mechanism of VOAS. Copyright © 2014 John Wiley & Sons, Ltd. PMID:25515821

  12. Ethanol extract of Angelica gigas inhibits croton oil-induced inflammation by suppressing the cyclooxygenase - prostaglandin pathway

    PubMed Central

    Shin, Sunhee; Joo, Seong Soo; Park, Dongsun; Jeon, Jeong Hee; Kim, Tae Kyun; Kim, Jeong Seon; Park, Sung Kyeong

    2010-01-01

    The anti-inflammatory effects of an ethanol extract of Angelica gigas (EAG) were investigated in vitro and in vivo using croton oil-induced inflammation models. Croton oil (20 µg/mL) up-regulated mRNA expression of cyclooxygenase (COX)-I and COX-II in the macrophage cell line, RAW 264.7, resulting in the release of high concentrations of prostaglandin E2 (PGE2). EAG (1~10 µg/mL) markedly suppressed croton oil-induced COX-II mRNA expression and PGE2 production. Application of croton oil (5% in acetone) to mouse ears caused severe local erythema, edema and vascular leakage, which were significantly attenuated by oral pre-treatment with EAG (50~500 mg/kg). Croton oil dramatically increased blood levels of interleukin (IL)-6 and PGE2 without affecting tumor-necrosis factor (TNF)-? and nitric oxide (NO) levels. EAG pre-treatment remarkably lowered IL-6 and PGE2, but did not alter TNF-? or NO concentrations. These results indicate that EAG attenuates inflammatory responses in part by blocking the COX-PGE2 pathway. Therefore, EAG could be a promising candidate for the treatment of inflammatory diseases. PMID:20195064

  13. The Methanol Extract of Angelica sinensis Induces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain Tumors

    PubMed Central

    Lai, Wen-Lin; Harn, Horng-jyh; Hung, Pei-Hsiu; Hsieh, Ming-Chang; Chang, Kai-Fu; Huang, Xiao-Fan; Liao, Kuang-Wen; Lee, Ming-Shih; Tsai, Nu-Man

    2013-01-01

    Glioblastoma multiforme (GBM) is a highly vascularized and invasive neoplasm. The methanol extract of Angelica sinensis (AS-M) is commonly used in traditional Chinese medicine to treat several diseases, such as gastric mucosal damage, hepatic injury, menopausal symptoms, and chronic glomerulonephritis. AS-M also displays potency in suppressing the growth of malignant brain tumor cells. The growth suppression of malignant brain tumor cells by AS-M results from cell cycle arrest and apoptosis. AS-M upregulates expression of cyclin kinase inhibitors, including p16, to decrease the phosphorylation of Rb proteins, resulting in arrest at the G0-G1 phase. The expression of the p53 protein is increased by AS-M and correlates with activation of apoptosis-associated proteins. Therefore, the apoptosis of cancer cells induced by AS-M may be triggered through the p53 pathway. In in vivo studies, AS-M not only suppresses the growth of human malignant brain tumors but also significantly prolongs patient survival. In addition, AS-M has potent anticancer effects involving cell cycle arrest, apoptosis, and antiangiogenesis. The in vitro and in vivo anticancer effects of AS-M indicate that this extract warrants further investigation and potential development as a new antibrain tumor agent, providing new hope for the chemotherapy of malignant brain cancer. PMID:24319475

  14. Phytoestrogens: a viable option?

    PubMed

    Russell, Lori; Hicks, G Swink; Low, Annette K; Shepherd, Jinna M; Brown, C Andrew

    2002-10-01

    Estrogen replacement therapy is one of the most commonly prescribed medicines in the United States by traditional medical professionals. Over the past decade, the market for complementary/ alternative therapies for hormone replacement has dramatically increased. Women are seeking more "natural" alternatives to treat menopausal symptoms. Well-designed randomized clinical trials are often lacking, as is the information on efficacy and safety. This article will review several popular herbal therapies for menopausal symptoms including phytoestrogens, black cohosh (Cimicifuga racemosa), dong quai (Angelica sinensis), chast tree (Vitex agnus-castus), and wild Mexican yam. Their use, mechanism of action, and adverse effects are outlined. PMID:12385490

  15. Genetic polymorphism of mitochondrial DNA in Dong, Gelao, Tujia, and Yi ethnic populations from Guizhou, China.

    PubMed

    Li, Binbin; Zhong, Fuguang; Yi, Hongsheng; Wang, Xianran; Li, Liangfang; Wang, Lilan; Qi, Xiaolan; Wu, Lifu

    2007-09-01

    To reveal the genetic structures and relationships of the four ethnic populations from the maternal inheritance and explore the origins and migrations of nationalities, the genetic polymorphism of mtDNA in Dong, Gelao, Tujia, and Yi populations from Guizhou was studied by direct sequencing of hypervariable segment I(HVS I) and PCR-RFLP of coding region. Thirty-seven (sub-) haplogroups were identified in the classification tree of mtDNA haplogroups. Haplogroup distributions and principal component (PC) analysis showed that the Dong has high frequencies of south-prevalent haplogroups, which indicates that it is a typically southern population. The Yi harbors high frequencies of the south-prevalent and northern-prevalent haplogroups, which demonstrates that it inherits the maternal characteristics from both southern and northern populations. The Yi and Gelao cluster together, the reason for which might be that their ancestries frequently underwent gene exchanges and mixtures. PMID:17884690

  16. Steady Thermal Conduction Far From Equilibrium in Ding-Dong Model

    NASA Astrophysics Data System (ADS)

    Sano, Mitsusada M.

    2006-09-01

    Thermal conduction very far from equilibrium in ding-dong model is investigated. If we apply a large temperature difference to a small system, it exhibits non-monotone temperature profile. This astonishing behavior is explained by two-component fluid model. As a conclusion, for a small system in very far from equilibrium, the definition of temperature by the variance of momentum becomes ambiguous.

  17. Lightning data observed with lightning location system in Guang-Dong Province, China

    Microsoft Academic Search

    Shui Ming Chen; Y. Du; Ling Meng Fan

    2004-01-01

    This paper presents an investigation into cloud-to-ground lightning activity data collected by a lightning detection system in the Guang-Dong Province, the southernmost in China. Annual lightning days are acquired and ground flash density maps are constructed from the database, which contains the information of more than one million flashes. The lightning days are compared with annual thunderstorm days collected by

  18. [Experimental study on aging effect of Angelica sinensis polysaccharides combined with cytarabine on human leukemia KG1alpha cell lines].

    PubMed

    Xu, Chun-Yan; Geng, Shan; Liu, Jun; Zhu, Jia-Hong; Zhang, Xian-Ping; Jiang, Rong; Wang, Ya-Ping

    2014-04-01

    The latest findings of our laboratory showed that Angelica sinensis polysaccharide (ASP) showed a definite effect in regulating the aging of hematopoietic stem cells. Leukemia is a type of malignant hematopoietic tumor in hematopoietic stem cells. There have been no relevant reports about ASP's effect in regulating the aging of leukemia cells. In this study, human acute myeloid leukemia (AML) KG1alpha cell lines in logarithmic growth phase were taken as the study object, and were divided into the ASP group, the cytarabine (Ara-C) group, the ASP + Ara-C group and the control group. The groups were respectively treated with different concentration of ASP, Ara-C and ASP + Ara-C for different periods, with the aim to study the effect of ASP combined with Ara-C in regulating the aging of human acute myeloid leukemia KG1alpha cell lines and its relevant mechanism. The results showed that ASP, Ara-C and ASP + Ara-C could obviously inhibit KG1alpha cell proliferation in vitro, block the cells in G0/G1 phase. The cells showed the aging morphological feature. The percentage of positive stained aging cells was dramatically increased, and could significantly up-regulate the expression of aging-related proteins P16 and RB, which were more obvious in the ASP + Ara-C group. In conclusion, the aging mechanism of KG1alpha cell induced by ASP and Ara-C may be related to the regulation of the expression of aging-related proteins, suggesting that the combined administration of ASP and anticancer drugs plays a better role in the treatment of leukemia . PMID:25011265

  19. Radix Angelica Sinensis that contains the component Z-ligustilide promotes adult neurogenesis to mediate recovery from cognitive impairment.

    PubMed

    Xin, Jiawei; Zhang, Junjian; Yang, Ying; Deng, Min; Xie, Xiaofeng

    2013-11-01

    Radix Angelica Sinensis (RAS) has beneficial effects in patients suffering from cognitive impairment associated with chronic cerebral hypoperfusion. It has previously been demonstrated that RAS prevents the neurotoxic effects of ?-amyloid (A?) in vitro, protects from injuries due to oxidative stress, inflammation and apoptosis and ameliorates scopolamine-induced amnesia in rats. Here, we studied the effects of RAS on cognitive improvement and neurogenic enhancement and examined the possible underlying mechanisms in a rat model with permanent bilateral common carotid artery occlusion, which serves as a model of chronic cerebral hypoperfusion-related neurodegenerative diseases. RAS enhances adult neurogenesis in the hippocampus following chronic cerebral hypoperfusion and improves the cognitive decline associated with hypoperfusion. Long-term ablation of adult hippocampal neurogenesis through cranial irradiation abolishes the protective effects of RAS on cognition. Furthermore, administration of RAS restores the decrease of brain-derived neurotrophic factor (BDNF) expression, the phosphorylation of cAMP-responsive element binding protein (CREB) and the glutamic acid decarboxylase 65 (GAD65) staining intensity in rats with chronic cerebral hypoperfusion. The present study supports the hypothesis that adult neurogenesis is required for RAS to facilitate recovery from the cognitive impairment induced by chronic cerebral hypoperfusion, while neurogenic enhancement secondary to RAS treatment may be due to increased BDNF and phosphorylated cAMP-responsive element binding protein (p-CREB) levels and increased ?-aminobutyric acid (GABA) expression. Based on the possible mechanisms suggested by the present study, this well-known traditional medicine may represent a candidate therapeutic agent for the treatment of dementia associated with vascular injury. PMID:23937197

  20. Effect of co-administration of Angelicae gigantis radix and Lithospermi radix on rat hepatic injury induced by carbon tetrachloride

    PubMed Central

    Lim, Chi-Yeon; Kim, Bu-Yeo; Lim, Se-Hyun; Cho, Su-In

    2015-01-01

    Background: Co-administration of Angelicae gigantis radix (AGR) and Lithospermi radix (LR) has been commonly applied to patients to treat cardiac and hepatic disorders. Individual bioactivities of these herbal medicines have been widely investigated, but the hepatoprotective effects of co-treatment of AGR and LR have yet to be clarified. Objective: The present study investigated the protective effects of extracts of AGR and LR on carbon tetrachloride (CCl4) induced hepatic injury. Materials and Methods: In this study, we measured the hepatoprotective activity of individual and co-treatment of the two herbal medicines on hepatic injury induced by CCl4 by measuring different biochemical parameters such as serum aspartate aminotransaminase (AST) and serum alanine aminotransaminase (ALT). Microarray technology also used to compare ontological difference with individual and co-treatment of these two. Results: Combined treatment with AGR and LR (AGR + LR) decreased AST and ALT level in serum which demonstrate hepatoprotective effect of the therapy. When the effect of AGR and LR according to treatment conditions was measured, co-treatment showed the most prominent effect on hepatic injury by CCl4 rather than individual treatment condition. We further defined gene set that could be the molecular target of herbal effect on hepatic injury by CCl4 using bioinformatical analysis of interaction network. Highly recovered genes by treating AGR + LR play significant roles in response to hepatic injury induced by CCl4. Conclusion: Combined treatment with AGR and LR showed synergistic protective effects on the CCl4-induced rat hepatic tissue injury. PMID:25829781

  1. Ethyl acetate extract from Angelica Dahuricae Radix inhibits lipopolysaccharide-induced production of nitric oxide, prostaglandin E 2 and tumor necrosis factor-? via mitogen-activated protein kinases and nuclear factor-?B in macrophages

    Microsoft Academic Search

    Ok-Hwa Kang; Go-Hoon Lee; Hyuk Joon Choi; Pil Sang Park; Hee-Sung Chae; Seung-Il Jeong; Youn-Chul Kim; Dong Hwan Sohn; Hyun Park; John Hwa Lee; Dong-Yeul Kwon

    2007-01-01

    Angelica dahurica (Umbelliferae) has been used to treat headache of common cold, supraorbital neuralgia, painful swelling on the body, nasal stuffiness, leukorrhea and arthralgia due to wind-dampness in Korean traditional medicine. It is also claimed to be effective in the treatment of acne, erythema, headache, toothache, sinusitis, colds and flu. The present study focused whether the ethyl acetate extract from

  2. Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein

    PubMed Central

    Chen, Chang; Wu, Chuanhong; Lu, Xinhua; Yan, Zhiyong; Gao, Jian; Zhao, Hui; Li, Shaojing

    2013-01-01

    Glutathione S-transferase (GST) is the key enzyme in multidrug resistance (MDR) of tumour. Inhibition of the expression or activity of GST has emerged as a promising therapeutic strategy for the reversal of MDR. Coniferyl ferulate (CF), isolated from the root of Angelica sinensis (Oliv.) Diels (Radix Angelicae sinensis, RAS), showed strong inhibition of human placental GST. Its 50% inhibition concentration (IC50) was 0.3??M, which was greater than a known GSTP1-1 inhibitor, ethacrynic acid (EA), using the established high-throughput screening model. Kinetic analysis and computational docking were used to examine the mechanism of GST inhibition by CF. Computational docking found that CF could be fully docked into the gorge of GSTP1-1. The further exploration of the mechanisms showed that CF was a reversible noncompetitive inhibitor with respect to GSH and CDNB, and it has much less cytotoxicity. Apoptosis and the expression of P-gp mRNA were evaluated in the MDR positive B-MD-C1 (ADR+/+) cell line to investigate the MDR reversal effect of CF. Moreover, CF showed strong apoptogenic activity and could markedly decrease the overexpressed P-gp. The results demonstrated that CF could inhibit GST activity in a concentration-dependent manner and showed a potential MDR reversal effect for antitumour adjuvant therapy. PMID:24058374

  3. Angelica sinensis polysaccharide regulates glucose and lipid metabolism disorder in prediabetic and streptozotocin-induced diabetic mice through the elevation of glycogen levels and reduction of inflammatory factors.

    PubMed

    Wang, Kaiping; Cao, Peng; Shui, Weizhi; Yang, Qiuxiang; Tang, Zhuohong; Zhang, Yu

    2015-03-11

    The present study was designed to evaluate the potential hypoglycemic and hypolipidemic effects of Angelica sinensis polysaccharide (ASP), purified from the fresh roots of Angelica sinensis (AS), in prediabetic and streptozotocin (STZ)-induced diabetic BALB/c mice. It was observed that fasting blood glucose (FBG) levels in both models were reduced after a 4-week oral administration of ASP or metformin, and abnormal fasting serum insulin (FINS) concentrations were ameliorated as well. Moreover, the homeostasis model assessment-insulin resistance (HOMA-IR) index was decreased strikingly and body weight (BW) was reduced significantly in prediabetic mice after treatment with ASP. In addition, ASP also contributed to improving the dyslipidemia conditions. Elevated serum total cholesterol (TC) or triglyceride (TG) concentrations were reduced after treatment with ASP in prediabetic mice or STZ-induced diabetic mice. Meanwhile, hepatic glycogen (HG) and muscle glycogen (MG) concentrations were increased while insulin resistance (IR)-related inflammatory factors IL-6 and TNF-? in serum were reduced in STZ-induced diabetic mice. Histopathological examination indicated that the impaired pancreatic/hepatic tissues or adipose tissues were effectively restored in STZ-induced diabetic mice or prediabetic mice after the ASP treatment. Taken together, these results revealed that ASP efficiently exerted hypoglycemic and hypolipidemic benefits, and its potential effect was associated with the amelioration of IR. ASP can be applied in the prevention and treatment of diabetes. PMID:25630053

  4. Long-term trend of climate variables in the upper Dong Nai river basin in Vietnam

    NASA Astrophysics Data System (ADS)

    Truong, Nguyen Cung Que; Nguyen, Hong Quan; Kondoh, Akihiko

    2015-04-01

    Dong Nai river and Mekong delta downstream are located in and supplied the major water resources to the whole Southern of Vietnam. In the state of continuous changes in water resources due to climate changes, there are several controversy about the potential impact of sediment transport and river flows downstream due to either the cascade hydroelectric power plant system or dam construction in the upper of Mekong delta. Therefore, management and planning for efficient use of Dong Nai river water resource is very important. Furthermore, that it is necessary to consider the hydrological regime change by the effects of climate variable. On the other hand, solving the problems of water shortage in the dry season and flood control in rainy season are also important for issues of water management at Dong Nai river basin. In this study we evaluated changes in two main factors of the water balance equation (both rainfall and evapotranspiration) to assess long-term change in the hydrological regime in the upper area of Dong Nai river basin. This key theme was divided into the following two sub-goals. The first goal was to analyze long term spatial and temporal rainfall trends. The second goal was to analyze the long-term trend of meteorological factors determining evapotranspiration such as air temperature, wind speed, solar radiation and sunshine duration. The results were used to assess their impact to evapotranspiration. The meteorological and hydrological data of the basin for the last 20 years (from 1993 to 2012) were analyzed based on the Empirical Mode Decomposition (EMD) method. The EMD method has been pioneered by Huang et al. (1998) for adaptively representing nonstationary time-series data as sum of zero-mean amplitude modulation-frequency modulation (AM-FM) components by iteratively conducting the sifting process. These components called Intrinsic Mode Functions (IMFs) allow the calculation of a meaningful multi-component instantaneous frequency. The results show temperature slightly increased of 2% in all areas and rainfall in rainy season increased of 10% in highland, 15% in midland and 5% in lowland. Whereas we have found the downtrend in all meteorological factors, while the reduction of wind speed were greatly with 15% but they are very small in related humidity (0.3%) and sunrise duration (1%). Solar radiation was slightly decreased of 8% and discharge was increased of 8% steadily. EMD is not only the quantitative results as above but it also shows shape of trend curves, from which we can verify change in climate variables in analyzed period. EMD could be widely used to detect trend over time of meteorological time series data.

  5. Dong, A. and A.M. Agogino, "Designing an Untethered Educational Digital Library" (with A. Dong), Proceedings of the IEEE International Workshop on Wireless and Mobile Technologies in Education (WMTE 2003).

    E-print Network

    Agogino, Alice M.

    an Untethered Educational Digital Library" (with A. Dong), Proceedings of the IEEE International Workshop, CA 94720-1740 +1 510 643 1819 aagogino@me.berkeley.edu ABSTRACT Digital libraries, such as the SMETE Digital Library at UC Berkeley (www.smete.org), are quickly becoming mainstream tools for science

  6. A Study on the characteristics of sediment transfer in Nak-dong estuary, South Korea

    NASA Astrophysics Data System (ADS)

    Jeon, Y.; Park, S.; Ryu, C.

    2006-12-01

    The continuous sediment transfer and the distinctive change of the estuary environment caused by large-scale construction have been observed in the Nak-dong estuary, Korea. Thus, investigation of the characteristics and the scale on the change of the sediment environment becomes necessary. In this study, field and numerical experiments were conducted to investigate characteristics of sediment transfer in the target area. In the field experiment, the resuspension bed loads were observed at five sites that were determined based on water way to find a distribution of sediment transfer and tidal flow was observed at one point for 20 days in February, 2006. The quantitative estimations of many resuspension bed loads, which can be the basic research to evaluate the sediment transformation, were performed. As results of these experiments, it was shown that the flux mount (g/cm2/day) of resuspension bed load was the highest in the southern part of Bakhaop and Jinwoo islands located in the Nak-dong estuary. In the numerical experiments using the results of the field experiments, distribution of current velocity was appeared 0.5 m/s at southern part of Sinja island and 0.2~0.3 m/s at eastern and southern parts of Jinwoo island. Thus deposition of sediment at south sea from Jinwoo island and at the area between Sinho and Jinwoo islands were expected.

  7. WEB-BASED TOOLS FOR ENGINEERING DESIGN ANIL VARMA, ANDY DONG, BALA CHIDAMBARAM AND ALICE M AGOGINO

    E-print Network

    Agogino, Alice M.

    WEB-BASED TOOLS FOR ENGINEERING DESIGN ANIL VARMA, ANDY DONG, BALA CHIDAMBARAM AND ALICE M AGOGINO Web as a source of information as well as a platform for collaboration in engineering design calls)- a prototype framework for Web-based design information resources management. The implementation of the Cdb

  8. Power Modeling of Graphical User Interfaces on OLED Mian Dong Yung-Seok Kevin Choi Lin Zhong

    E-print Network

    Zhong, Lin

    Power Modeling of Graphical User Interfaces on OLED Displays Mian Dong Yung-Seok Kevin Choi Lin Algorithms, Measurement, Human Factors Keywords OLED Display, Graphic User Interface, Low Power 1, optimization as well as energy- efficient GUI design, given the display content or even the graph- ical user

  9. Mining MultiDimensional Constrained Gradients in Data Cubes Guozhu Dong Jiawei Han Joyce Lam Jian Pei Ke Wang

    E-print Network

    Dong, Guozhu

    Mining Multi­Dimensional Constrained Gradients in Data Cubes #3; Guozhu Dong Jiawei Han Joyce Lam associated with big changes in measure in a data cube. Cells are considered similar if they are related and describe sectors of the business modeled by the data cube. The problem of mining changes of sophisticated

  10. Verifying IP-Core based System-On-Chip Designs Pankaj Chauhan, Edmund M. Clarke, Yuan Lu and Dong Wang

    E-print Network

    Clarke, Edmund M.

    Verifying IP-Core based System-On-Chip Designs Pankaj Chauhan, Edmund M. Clarke, Yuan Lu and Dong and for all, the standard bus interconnecting IP Cores in the system . The next task is to verify the glue logic, which connects the IP Cores to the buses. Finally, using the verified bus protocols and the IP

  11. BaFe2Se3: A High TC Magnetic Multiferroic with Large Ferrielectric Polarization Shuai Dong,1

    E-print Network

    Tennessee, University of

    and multiferroicity, the search for high TC superconductors (SCs) can help the magnetoelectric (ME) community of their superconducting properties [6]. However, to our knowledge the possibility of multiferroic behavior has not beenBaFe2Se3: A High TC Magnetic Multiferroic with Large Ferrielectric Polarization Shuai Dong,1 J

  12. REMOVAL OF PROCESSING AIDS FROM CERAMIC/POLYMER GREGORY C. STANGLE, DONG-JOO RHEE, AND ILHAN A. AKSAY

    E-print Network

    Aksay, Ilhan A.

    171 REMOVAL OF PROCESSING AIDS FROM CERAMIC/POLYMER COMPOSITES GREGORY C. STANGLE, DONG-JOO RHEE issues in the removal of processing aids from ceramic compacts prior to sintering have been investigated materials. The kinetics of pyrolytic degradation of organic processing aids were studied using

  13. Modeling and Detection of Camouflaging Worm Wei Yu, Xun Wang, Prasad Calyam, Dong Xuan, and Wei Zhao

    E-print Network

    Calyam, Prasad

    1 Modeling and Detection of Camouflaging Worm Wei Yu, Xun Wang, Prasad Calyam, Dong Xuan, and Wei them. In this paper, we investigate a new class of active worms, referred to as Camouflaging Worm (C manipulate its scan traffic volume over time. Thereby, the C-Worm camouflages its propagation from existing

  14. Rare blood donors screening by multiplex PCR methods in Chinese Zhuang and Dong population and pedigree analysis.

    PubMed

    Jiao, Wei; Liao, Xiangcheng; Li, Hailan; Lan, Jiao; Mo, Zhuning; Yang, Ziji; Liu, Fei; Xiao, Ruiping; He, Yulei; Ye, Luyi; Zhu, Ziyan

    2015-01-01

    There are little data available regarding the frequencies of the blood group antigens other than ABO and RhD in the Chinese Zhuang and Dong population. Knowledge of the antigen frequencies is important to assess risk of antibody formation and to guide the probability of finding antigen-negative donor blood, which is especially useful when blood is required for a patient who has multiple red cell alloantibodies. The aim of this study is sought to massively screen for rare blood donors with antigen-negative (e.g. Fy (a-), s-, k-, Di (b-) and Js (b-)) in an ethnic Zhuang and Dong population of China, for providing precious rare blood type materials which can be used to improve the capability of compatible infusion and reduce the transfusion reactions. Finally, inheritance of the Fy (a-), s-, k-, Di (b-) and Js (b-) phenotypes was investigated by pedigree analysis. We screened for Fy (a-), s-, k-, Di (b-) and Js (b-) phenotypes in blood donors by multiplex polymerase chain reaction. The rare phenotypes Fy (a-), s-, k-, Di (b-) and Js (b-) were verified by flow cytometry and sequencing analysis. The results indicated that there are five Fy (a-), three s (-), two Di (b-) in 4490 Zhuang random samples and three Fy (a-) in 1927 Dong random samples. In conclusion, this study is the first small step to create a rare donor data bank for Chinese Zhuang and Dong population and to prepare antigen negative compatible blood to patients with multiple alloantibodies. PMID:26064274

  15. Polymer Cushions Functionalized with Lipid Molecules Dong-Chan Lee, Bong-Jun Chang, Luping Yu,*, Shelli L. Frey,

    E-print Network

    Lee, Ka Yee C.

    Polymer Cushions Functionalized with Lipid Molecules Dong-Chan Lee, Bong-Jun Chang, Luping Yu of a biomimicking surface by modification of an end-functionalizable smooth polymer cushion constructed via of a phospholipid bilayer formed by vesicle fusion on the phospholipid-like molecule terminated polymer film

  16. Detecting Worms via Mining Dynamic Program Xun Wang, Wei Yu, Adam Champion, Xinwen Fu and Dong Xuan

    E-print Network

    Xuan, Dong

    Detecting Worms via Mining Dynamic Program Execution Xun Wang, Wei Yu, Adam Champion, Xinwen Fu and Dong Xuan Abstract-- Worm attacks have been major security threats to the Internet. Detecting worms, especially new, unseen worms, is still a challenging problem. In this paper, we propose a new worm detection

  17. Rare blood donors screening by multiplex PCR methods in Chinese Zhuang and Dong population and pedigree analysis

    PubMed Central

    Jiao, Wei; Liao, Xiangcheng; Li, Hailan; Lan, Jiao; Mo, Zhuning; Yang, Ziji; Liu, Fei; Xiao, Ruiping; He, Yulei; Ye, Luyi; Zhu, Ziyan

    2015-01-01

    There are little data available regarding the frequencies of the blood group antigens other than ABO and RhD in the Chinese Zhuang and Dong population. Knowledge of the antigen frequencies is important to assess risk of antibody formation and to guide the probability of finding antigen-negative donor blood, which is especially useful when blood is required for a patient who has multiple red cell alloantibodies. The aim of this study is sought to massively screen for rare blood donors with antigen-negative (e.g. Fy (a-), s-, k-, Di (b-) and Js (b-)) in an ethnic Zhuang and Dong population of China, for providing precious rare blood type materials which can be used to improve the capability of compatible infusion and reduce the transfusion reactions. Finally, inheritance of the Fy (a-), s-, k-, Di (b-) and Js (b-) phenotypes was investigated by pedigree analysis. We screened for Fy (a-), s-, k-, Di (b-) and Js (b-) phenotypes in blood donors by multiplex polymerase chain reaction. The rare phenotypes Fy (a-), s-, k-, Di (b-) and Js (b-) were verified by flow cytometry and sequencing analysis. The results indicated that there are five Fy (a-), three s (-), two Di (b-) in 4490 Zhuang random samples and three Fy (a-) in 1927 Dong random samples. In conclusion, this study is the first small step to create a rare donor data bank for Chinese Zhuang and Dong population and to prepare antigen negative compatible blood to patients with multiple alloantibodies.

  18. Germanium Telluride Nanowires and Nanohelices with Memory-Switching Dong Yu, Junqiao Wu, Qian Gu, and Hongkun Park*

    E-print Network

    Heller, Eric

    Germanium Telluride Nanowires and Nanohelices with Memory-Switching Behavior Dong Yu, Junqiao Wu, Qian Gu, and Hongkun Park* Department of Chemistry and Chemical Biology, HarVard UniVersity, 12 Oxford-change" compounds are the material bases for nonvolatile optical memory, such as CD and DVD,3 and they are now being

  19. Open access publishing and peer reviews : new models Marie Pascale Baligand, Cemagref, 3 bis quai Chauveau, 69336 Lyon cedex 09, France

    E-print Network

    Paris-Sud XI, Université de

    1 Open access publishing and peer reviews : new models Marie Pascale Baligand, Cemagref, 3 bis quai: In the traditional scientific publishing business, journals limit access to subscribers or sell articles on a pay per to publish papers rapidly while accessing peer review and publishing discussion papers enabling interactive

  20. Cohort Profile: The Namwon Study and the Dong-gu Study.

    PubMed

    Kweon, Sun-Seog; Shin, Min-Ho; Jeong, Seul-Ki; Nam, Hae-Sung; Lee, Young-Hoon; Park, Kyeong-Soo; Ryu, So-Yeon; Choi, Seong-Woo; Kim, Bok-Hee; Rhee, Jung-Ae; Zheng, Wei; Choi, Jin-Su

    2014-04-01

    These two cohorts were designed to examine the increasing burden of chronic diseases among Korean populations. The studies investigated determinants for stroke, osteoporosis, dementia and cancer among middle-aged and elderly Korean populations. The Namwon Study baseline survey was performed between 2004 and 2007 (n = 10 667), and followed up 4 years later (n = 8157, follow-up rate = 76.5%). The baseline survey of the Dong-gu Study was administered over 2007-2010 (n = 9260), and will be followed up between 2014 and 2015. Questionnaires included assessment of cognitive function, psychiatric health and lifestyle factors. Clinical examinations, biochemical tests and genotyping focused on evaluating the determinants of target diseases and their intermediate phenotypes. Potential collaborators will be invited to contact the chief investigators. PMID:23505254

  1. [Professor DONG Gui-rong's experience for the treatment of peripheral facial paralysis].

    PubMed

    Cao, Lian-Ying; Shen, Te-Li; Zhang, Wei; Chen, Si-Hui

    2012-05-01

    Professor DONG Gui-rong's theoretical principle and manipulation points for peripheral facial paralysis were introduced in details from the angels of syndrome differentiation, timing, acupoint prescription and needling methods. For the syndrome differentiation and timing, the professor emphasized to check the treatment timing and follow the symptoms, which should be treated by stages, besides, it was necessary to find and distinguish the reason and nature of diseases to have a combined treatment of tendons and muscles. For the acupoint prescription and needling methods, he has proposed that the acupoints selection should be compatible of distal and lacal, and made a best of Baihui (GV 20) to regulate the whole yang qi, also he has paid much attention to the needling methods and staging treatment. Under the consideration of late stage of peripheral facial paralysis, based on syndrome differentiation Back-shu points have been selected to regulate zang-fu function, should achieve much better therapeutic effect. PMID:22650134

  2. [Professor Dong Gui-rong's experiences in treatment of child cerebral palsy].

    PubMed

    Yang, Guan-nan; Li, Cheng-jia; Bao, Chun-ling

    2014-09-01

    According to the characteristics of the etiology and pathogenesis of child cerebral palsy, on the basis of "regulating the mind in treatment of all kinds of diseases" and "regulating the functions of five zang organs with back-shu points", Professor DONG Gui-rong applied the penetrating needling technique on the scalp points and acupuncture at back-shu points of five zang organs in the treatment of child cerebral palsy. The valuable clinical experiences have been summarized as "regulating the mind with scalp needling technique, benefiting the brain and opening the orifice", "regulating five zang organs with back-shu points" and "integration of acupuncture and rehabilitation, and function reconstruction". Two effective cases were introduced. PMID:25509746

  3. Quasiperiodic and Chaotic States in the Ding-Dong Model for N=3

    NASA Astrophysics Data System (ADS)

    Gawronski, P.; Kulakowski, K.

    The system considered is a chain of spheres bound harmonically to equidistant points and colliding elastically. This is the so-called ``ding-dong'' model of Prosen and Robnik, 1992. For 3 spheres we investigate the transition from chaos to quasiperiodicity in a numerical experiment. The character of motion is determined by calculation of the box counting fractal dimension of the t(n+1) versus t(n) plot, where t(n) is a time between an nth and an (n+1)th collision between spheres. The result is that the transition occurs at many regions of the phase space for all values of the total energy. We conclude that, in the contrast to what was suggested by other authors, the character of motion cannot be deduced from one parameter.

  4. Population study of three STR loci -- HUMTH01, TPOX and CSF1PO in Dong-xiang, Hui and Han from northwest China.

    PubMed

    Xunling, X X; Xiaolin, H; Xiaolin, R G

    2001-06-15

    The multiplex amplification system of three tetrameric short tandem repeats loci (HUMTH01, TPOX and CSF1PO) were studied in Dong-xiang, Hui and Han ethnic groups from northwest China. All loci meet the Hardy-Weinberg equilibrium by three tests. The allelic frequency data are statistically similar for three ethnic groups. This is the first time that Chinese Dong-xiang and Hui population data of DNA loci of forensic importance are reported. PMID:11376993

  5. Dental morphology of the early Hoabinian, the Neolithic Da But and the Metal age Dong Son civilized peoples in Vietnam.

    PubMed

    Matsumura, H; Cuong, N L; Thuy, N K; Anezaki, T

    2001-01-01

    The early Hoabinian, the Neolithic Da But and the Dong Son (early Metal age) civilized peoples in northern Vietnam were investigated based on dental morphology and were compared with specimens from surrounding Northeast and Southeast Asia including Australians and Melanesians. In both the metric and nonmetric tooth traits, the Hoabinian and Da But specimens had dental features similar to the prehistoric Southeast Asians and the Australo-Melanesians, but also had partially Northeast Asian characteristics. On the other hand, the Northeast Asian features become distinct in the dentition of the Dong Son people, which have close ties with the modern Vietnamese. Thus, the Vietnamese, as well as the other modern Southeast Asians and Japanese, are considered to be a blend of indigenous Southeast Asians who are closely related to the Australo-Melanesian lineage, and migrants from Northeast Asia. PMID:11372468

  6. A Correction to the article "Geo-center movement caused by huge earthquakes" by Wenke Sun and Jie Dong

    NASA Astrophysics Data System (ADS)

    Zhou, Jiangcun; Sun, Wenke; Dong, Jie

    2015-07-01

    Sun and Dong (2014) studied the co-seismic geo-center movement using dislocation theory for a spherical earth model. However, they incorrectly considered the maximum vertical co-seismic displacement as the rigid geo-center motion (i.e., they did not separate the rigid shift and elastic deformation). In this paper, we correct Sun and Dong (2014) by using a new approach. We now define the geo-center motion as a shift of the center of figure of the Earth relative to the center of mass of the Earth. Furthermore, we derive new formulas to compute the co-seismic geo-center and inner core's center movements caused by huge earthquakes. The 2004 Sumatra earthquake and the 2011 Tohoku-Oki earthquake changed the geo-center by 1-4 mm and about 2 mm, respectively, and caused the inner core's center to displace by about 0.05 mm and 0.025 mm, respectively.

  7. c h i c a g o fall books Cover illustration: "Bouquiniste sur le quai des Grands-Augustins." Oil on

    E-print Network

    Mateo, Jill M.

    c h i c a g o fall books 2 0 1 4 #12;Cover illustration: "Bouquiniste sur le quai des Grands Carnavalet/Roger-Viollet/The Image Works. From Palace of Books by Roger Grenier, translated from the French $26.00/£18.00 E-book ISBN-13: 978-0-226-13864-0 On the Run Fugitive Life in an American City Alice

  8. Data Mining of Acupoint Characteristics from the Classical Medical Text: DongUiBoGam of Korean Medicine

    PubMed Central

    Lee, Taehyung; Jung, Won-Mo; Lee, In-Seon; Lee, Ye-Seul; Lee, Hyejung; Park, Hi-Joon; Kim, Namil; Chae, Younbyoung

    2014-01-01

    Throughout the history of East Asian medicine, different kinds of acupuncture treatment experiences have been accumulated in classical medical texts. Reexamining knowledge from classical medical texts is expected to provide meaningful information that could be utilized in current medical practices. In this study, we used data mining methods to analyze the association between acupoints and patterns of disorder with the classical medical book DongUiBoGam of Korean medicine. Using the term frequency-inverse document frequency (tf-idf) method, we quantified the significance of acupoints to its targeting patterns and, conversely, the significance of patterns to acupoints. Through these processes, we extracted characteristics of each acupoint based on its treating patterns. We also drew practical information for selecting acupoints on certain patterns according to their association. Data analysis on DongUiBoGam's acupuncture treatment gave us an insight into the main idea of DongUiBoGam. We strongly believe that our approach can provide a novel understanding of unknown characteristics of acupoint and pattern identification from the classical medical text using data mining methods. PMID:25574179

  9. Comparative analysis of main aromatic acids and phthalides in Angelicae Sinensis Radix, Chuanxiong Rhizoma, and Fo-Shou-San by a validated UHPLC-TQ-MS/MS.

    PubMed

    Li, Weixia; Tang, Yuping; Qian, Yefei; Shang, Erxin; Wang, Linyan; Zhang, Li; Su, Shulan; Duan, Jin-ao

    2014-10-01

    Fo-Shou-San (FSS) is an ancient and classic formula comprised of Angelicae Sinensis Radix (Danggui, DG) and Chuanxiong Rhizoma (Chuanxiong, CX) in a weight ratio of 3:2 with nourishing blood and dissipating blood stasis activities for the treatment of blood deficiency and blood stasis. In this study, a ultra-high-performance liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry (UHPLC-TQ-MS/MS) method was developed for simultaneous quantification of three aromatic acids (chlorogenic acid, caffeic acid, ferulic acid) and six phthalides (senkyunolide I, senkyunolide H, senkyunolide A, butylphthalide, ligustilide and butylidenephthalide) in DG, CX and FSS. The nine components were simultaneously determined within 10min. The proposed method was fully validated in terms of linearity, sensitivity, precision, repeatability as well as recovery. The results showed that there were significant differences in their contents of DG and CX, and there were remarkable differences between the theorized content and observed content in FSS. The content of each component in formulae was not just the simple addition among its content in the single herbs. These research results might be helpful to illustrate the drug interactions during decocting process of herb pair according to the quantity changes of these marker compounds, which would lay foundation to further reveal the compatibility rule of the herb pair and other related formulae. PMID:25061713

  10. Inhibition of inflammation and oxidative stress by Angelica dahuricae radix extract decreases apoptotic cell death and improves functional recovery after spinal cord injury.

    PubMed

    Moon, Youn Joo; Lee, Jee Youn; Oh, Myung Sook; Pak, Youngmi Kim; Park, Kang-Sik; Oh, Tae Hwan; Yune, Tae Young

    2012-01-01

    Inflammation and oxidative stress play major roles in the pathogenesis after spinal cord injury (SCI). Here, we examined the neuroprotective effects of Angelica dahuricae radix (ADR) extract after SCI. ADR extract significantly decreased the levels of proinflammatory factors such as tumor necrosis factor-? (TNF-?), interleukin-1? (IL-1?), interleukin-6 (IL-6), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) in a lipopolysaccharide (LPS)-activated microglial cell line, BV2 cells. ADR extract also significantly alleviated the level of reactive oxygen species in LPS-activated BV2 cells. To examine the neuroprotective effect of ADR extract after SCI, spinally injured rats were administered ADR extract orally at a dose of 100 mg/kg for 14 days. ADR extract treatment significantly reduced the levels of TNF-?, IL-1?, IL-6, iNOS, and COX-2. The levels of superoxide anion (O(2·)(-)) and protein nitration were also significantly decreased by ADR extract. In addition, ADR extract inhibited p38 mitogen-activated protein kinase activation and pronerve growth factor expression in microglia after SCI. Furthermore, ADR extract significantly inhibited caspase-3 activation following apoptotic cell death of neurons and oligodendrocytes, thereby improving functional recovery after injury. Thus, our data suggest that ADR extract provides neuroprotection by alleviating inflammation and oxidative stress and can be used as an orally administered therapeutic agent for acute SCI. PMID:21922518

  11. Quantitative analysis of phenolic metabolites from different parts of Angelica keiskei by HPLC-ESI MS/MS and their xanthine oxidase inhibition.

    PubMed

    Kim, Dae Wook; Curtis-Long, Marcus J; Yuk, Heung Joo; Wang, Yan; Song, Yeong Hun; Jeong, Seong Hun; Park, Ki Hun

    2014-06-15

    Angelica keiskei is used as popular functional food stuff. However, quantitative analysis of this plant's metabolites has not yet been disclosed. The principal phenolic compounds (1-16) within A. keiskei were isolated, enabling us to quantify the metabolites within different parts of the plant. The specific quantification of metabolites (1-16) was accomplished by multiple reaction monitoring (MRM) using a quadruple tandem mass spectrometer. The limit of detection and limit of quantitation were calculated as 0.4-44 ?g/kg and 1.5-148 ?g/kg, respectively. Abundance and composition of these metabolites varied significantly across different parts of plant. For example, the abundance of chalcones (12-16) decreased as follows: root bark (10.51 mg/g)>stems (8.52 mg/g)>leaves (2.63 mg/g)>root cores (1.44 mg/g). The chalcones were found to be responsible for the xanthine oxidase (XO) inhibition shown by this plant. The most potent inhibitor, xanthoangelol inhibited XO with an IC50 of 8.5 ?M. Chalcones (12-16) exhibited mixed-type inhibition characteristics. PMID:24491695

  12. Perimenopause Amelioration of a TCM Recipe Composed of Radix Astragali, Radix Angelicae Sinensis, and Folium Epimedii: An In Vivo Study on Natural Aging Rat Model

    PubMed Central

    Su, Ji-Yan; Xie, Qing-Feng; Liu, Wei-Jin; Lai, Ping; Liu, Dan-Dan; Tang, Li-Hai; Dong, Tina T. X.; Tsim, Karl W. K.; Lai, Xiao-Ping; Li, Kun-Yin

    2013-01-01

    Traditional Chinese medicine (TCM) has been extensively applied as preferable herbal remedy for menopausal symptoms. In the present work, the potential of a TCM recipe named RRF, composed of Radix Astragali, Radix Angelicae Sinensis, and Folium Epimedii, was investigated on a natural aging rat model. After administration of RRF (141, 282, and 564?mg/kg/d), the circulated estradiol (E2) level increased accompanied by a reduction of serum follicle stimulating hormone (FSH). But no significant impact on serum lutenizing hormone (LH) level was observed. As a result of the E2-FSH-LH adjustment, the histomorphology degenerations of ovary, uterus, and vagina of the 11.5-month female rats were alleviated. And lumbar vertebrae trabecular microstructure was also restored under RRF exposure by means of increasing the trabecular area and area rate. Moreover, levels of hypothalamic dopamine (DA) and norepinephrine (NE) rallied significantly after RRF treatment. Results from our studies suggest that RRF possesses a positive regulation on the estrogen imbalance and neurotransmitter disorder, thereby restoring reproductive organ degeneration and skeleton deterioration. The above-mentioned benefits of RRF on the menopause syndromes recommend RRF as a potential candidate for the treatment of perimenopausal syndrome. PMID:24454513

  13. Transport of Twelve Coumarins from Angelicae Pubescentis Radix across a MDCK-pHaMDR Cell Monolayer-An in Vitro Model for Blood-Brain Barrier Permeability.

    PubMed

    Yang, Yan-Fang; Xu, Wei; Song, Wei; Ye, Min; Yang, Xiu-Wei

    2015-01-01

    Angelicae Pubescentis Radix (APR), a widely used traditional Chinese medicine, is reported to have central nervous system activities. The purpose of this study was to characterize the blood-brain barrier permeability of twelve coumarins from APR including umbelliferone (1), osthol (2), scopoletin (3), peucedanol (4), ulopterol (5), angepubebisin (6), psoralen (7), xanthotoxin (8), bergapten (9), isoimperatorin (10), columbianadin (11), and columbianetin acetate (12) with an in vitro model using a MDCK-pHaMDR cell monolayer. The cell monolayer was validated to be suitable for the permeation experiments. The samples' transports were analyzed by high performance liquid chromatography and their apparent permeability coefficients (Papp) were calculated. According to the Papp value, most coumarins could be characterized as well-absorbed compounds except for 4, 10 and 11 which were moderately absorbed ones, in concentration-dependent and time-dependent manners. The results of P-glycoprotein (P-gp) inhibitor (verapamil) experiments showed that the transport of coumarin 4 was affected by the transport protein P-gp. Sigmoid functions between permeability log(Papp AP-BL*MW0.5) and log D (at pH 7.4) were established to analyze the structure-activity relationship of coumarins. The results provide useful information for discovering the substance basis for the central nervous system activities of APR, and predicting the permeability of other coumarins through BBB. PMID:26121397

  14. New coumarins from the roots of Angelica dahurica var. formosana cv. Chuanbaizhi and their inhibition on NO production in LPS-activated RAW264.7 cells.

    PubMed

    Deng, Gai-Gai; Wei, Wei; Yang, Xiu-Wei; Zhang, You-Bo; Xu, Wei; Gong, Ning-Bo; Lü, Yang; Wang, Feng-Feng

    2015-03-01

    A new linear pyranocoumarin named (-)-hydroxydecursinol (1) and a new biscoumarin named (±)-dahuribiscoumarin (2), together with six known compounds isoimperatorin (3), imperatorin (4), phellopterin (5), isodemethylfuropinarine (6), demethylfuropinarine (7), and (+)-decursinol (8) were isolated from the 75% ethanolic extract of the roots of Angelica dahurica var. formosana cv. Chuanbaizhi. Their structures were elucidated by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry, and the structure of 2 was confirmed by single-crystal X-ray diffraction. All of the isolated compounds were evaluated for the inhibition against nitric oxide (NO) production in the lipopolysaccharide (LPS)-activated RAW264.7 macrophage cell line, and exhibited the inhibitory activity on NO production in a concentration-dependent manner. Furthermore, real-time PCR analysis revealed that compounds 2, 5-8 could significantly suppress the expression levels of inducible nitric oxide synthase mRNA in a concentration-dependent manner. And their primary structure-activity relationships of NO inhibitory effects were also briefly discussed. These compounds are potential candidates for further bioassay studies to determine their suitability as drug leads. PMID:25647326

  15. Efficacy of Angelica archangelica essential oil, phenyl ethyl alcohol and ?- terpineol against isolated molds from walnut and their antiaflatoxigenic and antioxidant activity.

    PubMed

    Prakash, Bhanu; Singh, Priyanka; Goni, Reema; Raina, Ajay Kumar Pandit; Dubey, N K

    2015-04-01

    Mold association, aflatoxin B1 contamination as well as oxidative deterioration of agri-food items during storage and processing are some global task for food industries. In view of the adverse effects of some synthetic preservatives on treated food items and subsequently on consumers health, recently plant based chemicals are encouraged by food industries as better alternatives of synthetics. The present study recommends the combination (1:1:1) of Angelica archangelica essential oil: Phenyl ethyl alcohol (PEA): ?- terpineol as botanical preservative against molds, aflatoxin contamination and oxidative deterioration of walnut samples. Eight mold species were procured from stored walnut samples, including some aflatoxigenic Aspergillus flavus strains. The combination inhibited growth of aflatoxigenic strain Aspergillus flavus NKDW-7 and aflatoxin B1 production at 2.25 and 2.0 ?L mL(-1) respectively. The IC50 value of the combination was recorded as 3.89 ?L mL(-1), showing strong antioxidant potential. The antifungal action of the combination showed?>?90 % decrease in ergosterol content in plasma membrane of A. flavus at 2.0 ?L mL(-1). The LD50 of the combination, through oral administration on mice, was 9562.9 ?L kg(-1) body weight, indication favourable safety profile as a plant based preservative. The combination may be recommended as safe preservative against molds, aflatoxin contamination and oxidative deterioration of walnut samples. PMID:25829603

  16. The epidemiology of typhoid fever in the Dong Thap Province, Mekong Delta region of Vietnam.

    PubMed

    Lin, F Y; Vo, A H; Phan, V B; Nguyen, T T; Bryla, D; Tran, C T; Ha, B K; Dang, D T; Robbins, J B

    2000-05-01

    A population-based surveillance for typhoid fever was conducted in three rural communes of Dong Thap Province in southern Vietnam (population 28,329) for a 12-month-period starting on December 4, 1995. Cases of typhoid fever were detected by obtaining blood for culture from residents with fever > or = 3 days. Among 658 blood cultures, 56 (8.5%) were positive for Salmonella typhi with an overall incidence of 198 per 10(5) population per year. The peak occurrence was at the end of the dry season in March and April. The attack rate was highest among 5-9 year-olds (531/10(5)/year), and lowest in > 30 year-olds (39/10(5)/year). The attack rate was 358/10(5)/year in 2-4 year-olds. The isolation of S. typhi from blood cultures was highest (17.4%) in patients with 5 to 6 days of fever. Typhoid fever is highly endemic in Vietnam and is a significant disease in both preschool and school-aged children. PMID:11289678

  17. Capabilities of three satellite images to map coral reefs at Dong-Sha Atoll

    NASA Astrophysics Data System (ADS)

    Chen, Jianyu; Mao, Zhihua; Pan, Delu; He, Xianqiang

    2006-12-01

    Coral reefs are complex marine ecosystems and environment-sensitive that are constructed and maintained by biological communities that thrive in the warm tropical ocean. Remote sensing provides a more efficient way to observe and monitor shallow coral reefs than alternative field survey. Dong-Sha Atoll is located at the northern continental margin of the South China Sea. The area of the atoll is more than 300 km2 with an average depth of 10 m, and has being abused by destructive fishing during recent decades. In this paper, three satellite broadband multi-spectral imageries (Quickbird2, ETM+, and SPOT5) are used to survey this area. In the preprocessing, low-resolution images are geometrically corrected to high-resolution imagery. For information extraction, unsupervised classification functions are adopted for ETM+ and SPOT5 data, and supervised classification method for Quickbird2. The classification results are (or not) merged into coral reef, and operated by vectorization, simplification, and topological analysis. There are 1331 coral reefs larger than 100 m2 with the detection limitation of 3×3 pixels at multi-band data of Quickbird2. The results extracted from SPOT5 data are better than that of ETM data at silty lagoon due to its higher resolution, and less at atoll reef bodies in the absence of blue waveband.

  18. Isolation and characterization of lactic acid bacteria from Yan-dong-gua (fermented wax gourd), a traditional fermented food in Taiwan.

    PubMed

    Lan, Wei-Tse; Chen, Yi-Sheng; Yanagida, Fujitoshi

    2009-12-01

    Yan-dong-gua (fermented wax gourd; a traditional fermented food in Taiwan) samples were collected at five time intervals from a fixed fermenting bucket. Eighty-five cultures of lactic acid bacteria (LAB) were isolated from Yan-dong-gua samples, and the isolates were divided into classes by phenotype and then groups by restriction fragment length polymorphism analysis and sequencing of 16S ribosomal DNA. Phenotypic and biochemical characteristics identified two bacterial groups (A and B) and showed that the majority of the isolates were heterofermentative LAB. Weissella cibaria was the major LAB found during the initial fermentation of yan-dong-gua. However, it was mostly replaced by W. paramesenteroides after 5 days of fermentation. All isolated LAB were able to grow in MRS broth containing 6% NaCl. Furthermore, the antibacterial activities of the isolates were determined, and five of the isolates showed inhibitory activities against the indicator strain Lactobacillus sakei subsp. sakei JCM 1157(T). These results suggest that W. cibaria and W. paramesenteroides are the main LAB present during the fermentation of yan-dong-gua. This is the first report describing the distribution and varieties of LAB that exist in the yan-dong-gua fermentation process. PMID:19914580

  19. The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry.

    PubMed

    Ahn, Mi-Jeong; Lee, Mi Kyeong; Kim, Young Choong; Sung, Sang Hyun

    2008-01-22

    An high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry (HPLC-DAD/MS) based method has been developed for the simultaneous determination of nine coumarin compounds, nodakenin (1), peucedanone (2), marmesin (3), decursinol (4), 7-hydroxy-6-(2R-hydroxy-3-methylbut-3-enyl)coumarin (5), demethylsuberosin (6), decursin (7), decursinol angelate (8) and isoimperatorin (9) in the Korean medicinal herb, Cham-Dang-Gui, the dried root of Angelica gigas (Umbelliferae). The methanol extracts were analyzed by HPLC using a reversed-phase C18 column (5 microm, 4.5 mm x 250 mm) using a gradient acetonitrile-water solvent system at a flow rate of 1.0 ml/min. The analysis of six coumarins (1, 3, 4 and 6-8) with DAD was done at 330 nm and showed excellent linearity (r(2)=0.998-0.999) in a range of 0.2-250 microg/ml for all the compounds. The average recoveries (n=3) were between 96.5% and 110.8%. Identification of each peak was also discussed with the electrospray ionization multi-stage tandem mass spectroscopy (ESI-MS(n)). The amount of these coumarin compounds was evaluated in A. gigas samples. Meanwhile, three coumarins (2, 5 and 9) could not been quantified by DAD because these peaks were overlapped with others. Determination of these compounds could be successfully accomplished with the HPLC-ESI/MS in selected ion monitoring/selected reaction monitoring mode. PMID:17997069

  20. Efficacy and safety of modified Mai-Men-Dong-Tang for treatment of allergic asthma.

    PubMed

    Hsu, Ching Hsaing; Lu, Chun Mei; Chang, Tung Ti

    2005-02-01

    The aim of this study was to evaluate the efficacy and safety of a Chinese herbal formula modified Mai-Men-Dong-Tang (mMMDT) for treatment of persistent, mild-to-moderate asthma. A total of 100 asthmatic patients were enrolled and assigned to three treatment groups in this double-blind, randomized, placebo-controlled clinical trial. Over a period of 4 months, patients in groups A and B received 80 and 40 mg/kg/day of mMMDT, while those in group C received a placebo. Efficacy variables included changes in forced expiratory volume in 1 s (FEV1), symptom score, serum total immunoglobulin E (IgE), and dust mite-specific IgE. Safety assessments included complete blood count, and liver and kidney function. Relative to baseline, significantly greater increases in FEV1 were demonstrated for both A and B groups in comparison with the placebo-treated analog (both p <0.05). Further, similar improvements in symptom score were observed for both mMMDT treatment groups. The serum total IgE for group A showed a decreasing tendency after treatment but no statistical difference was noted. Furthermore, no drug-related adverse effects were reported. Blood test, and liver and kidney function were within normal range during the study, with no marked changes demonstrated over time. In conclusion, the Chinese herbal formula mMMDT provided improvements in lung function and relieved asthma symptoms in our sample of patients. Given its efficacy and safety, we consider mMMDT a credible treatment regimen for persistent, mild-to-moderate asthma. PMID:15693916

  1. Fifteen Years After the Gozan-Dong Glass Fiber Outbreak, Incheon in 1995

    PubMed Central

    Cho, Soo-Hun; Kim, Jonghoon; Ju, Young-Su; Han, Minji; Jung, Kyu-Won

    2011-01-01

    Objectives In 1995, an outbreak survey in Gozan-dong concluded that an association between fiberglass exposure in drinking water and cancer outbreak cannot be established. This study follows the subjects from a study in 1995 using a data linkage method to examine whether an association existed. The authors will address the potential benefits and methodological issues following outbreak surveys using data linkage, particularly when informed consent is absent. Methods This is a follow-up study of 697 (30 exposed) individuals out of the original 888 (31 exposed) participants (78.5%) from 1995 to 2007 assessing the cancer outcomes and deaths of these individuals. The National Cancer Registry (KNCR) and death certificate data were linked using the ID numbers of the participants. The standardized incidence ratio (SIR) and standardized mortality ratio (SMR) from cancers were calculated by the KNCR. Results The SIR values for all cancer or gastrointestinal cancer (GI) occurrences were the lowest in the exposed group (SIR, 0.73; 95% CI, 0.10 to 5.21; 0.00 for GI), while the two control groups (control 1: external, control 2: internal) showed slight increases in their SIR values (SIR, 1.18 and 1.27 for all cancers; 1.62 and 1.46 for GI). All lacked statistical significance. All-cause mortality levels for the three groups showed the same pattern (SMR 0.37, 1.29, and 1.11). Conclusions This study did not refute a finding of non-association with a 13-year follow-up. Considering that many outbreak surveys are associated with a small sample size and a cross-sectional design, follow-up studies that utilize data linkage should become standard procedure. PMID:21894067

  2. Low Voltage High-SNR Pipeline Data Converters Charles Myers, Jipeng Li, Dong-Young Chang, and Un-Ku Moon

    E-print Network

    Moon, Un-Ku

    Low Voltage High-SNR Pipeline Data Converters Charles Myers, Jipeng Li, Dong-Young Chang, and Un pipeline data converter. This is accomplished with the removal of the S/H input stage and the use of a rail limitations. In pipeline data converters, noise reduction options such as oversampling and noise shaping

  3. Charles Nielsen; Jan Larsen; Kristian Morgen, DONG Energy, Kraftsvaerksvej 53, 7000 Fredericia, Denmark Security of supply, sustainability and the market are controlling parameters for developing the energy

    E-print Network

    Bioethanol Charles Nielsen; Jan Larsen; Kristian Morgen, DONG Energy, Kraftsvaerksvej 53, 7000 for developing the energy system. Bioethanol is part of the solution to the question about security of supply and the demand for a sustainable development, and all over Europe 1st generation bioethanol plants are being

  4. PLANAR DEVICE ISOLATION FOR InP BASED DHBTs N. Parthasarathy, Y. Dong, D. Scott, M. Urteaga and M.J.W. Rodwell

    E-print Network

    Rodwell, Mark J. W.

    PLANAR DEVICE ISOLATION FOR InP BASED DHBTs N. Parthasarathy, Y. Dong, D. Scott, M. Urteaga and M Barbara, CA 93106 Phone: (805) 893-8044 Fax: (805) 893-5705 Email: navin@ece.ucsb.edu Device isolation of InP based HBTs in the mesa technology, is done by etching down to the substrate; this process suffers

  5. Thermoelectric transport of massive Dirac fermions in bilayer graphene Seung-Geol Nam,1 Dong-Keun Ki,1,2 and Hu-Jong Lee1,*

    E-print Network

    Lee, Hu-Jong

    , the transverse thermoelectric conductiv- ity xy of bilayer graphene was measured, mainly in the quantum HallThermoelectric transport of massive Dirac fermions in bilayer graphene Seung-Geol Nam,1 Dong Received 19 September 2010; published 10 December 2010 Thermoelectric power TEP is measured in bilayer

  6. 2012;72:3038-3047. Published OnlineFirst April 24, 2012.Cancer Res Xiumei Huang, Ying Dong, Erik A. Bey, et al.

    E-print Network

    Gao, Jinming

    spectrum of therapeutically challenging solid tumors, such as pancreatic and lung cancers. Cancer Res; 72, pancreatic, and breast (2­4), for drug development. NQO1 is an inducible phase II detoxi- fying 2-electron2012;72:3038-3047. Published OnlineFirst April 24, 2012.Cancer Res Xiumei Huang, Ying Dong, Erik A

  7. A Comparison of MERRA and NARR Reanalyses with the DOE ARM SGP Data AARON D. KENNEDY, XIQUAN DONG, AND BAIKE XI

    E-print Network

    Dong, Xiquan

    A Comparison of MERRA and NARR Reanalyses with the DOE ARM SGP Data AARON D. KENNEDY, XIQUAN DONG from the Modern-Era Retrospective analysis for Research and Applications (MERRA) and the North American biases oc- curring during the spring upwelling and summer downwelling periods. Although NARR and MERRA

  8. Modulating Amyloid Self-Assembly and Fibril Morphology with Zn(II) Jijun Dong, Jacob E. Shokes, Robert A. Scott, and David G. Lynn*,

    E-print Network

    Scott, Robert A.

    Modulating Amyloid Self-Assembly and Fibril Morphology with Zn(II) Jijun Dong,§ Jacob E. Shokes, Robert A. Scott, and David G. Lynn*,§ Center for the Analysis of SupraMolecular Self-assemblies the energetics of higher order protein folding and assembly. These fibril arrays are generally viewed as rich

  9. Query Processing with An FPGA Coprocessor Board Jack S.N. Jean, Guozhu Dong, Hwa Zhang, Xinzhong Guo, and Baifeng Zhang

    E-print Network

    Dong, Guozhu

    Query Processing with An FPGA Coprocessor Board Jack S.N. Jean, Guozhu Dong, Hwa Zhang, Xinzhong a commercial FPGA coprocessor board is used to accelerate the processing of queries on a relational database that contains texts and images. FPGA designs for text searching and image matching are described

  10. Simultaneous determination of bioactive components of Radix Angelicae Sinensis-Radix Paeoniae Alba herb couple in rat plasma and tissues by UPLC-MS/MS and its application to pharmacokinetics and tissue distribution.

    PubMed

    Luo, Niancui; Li, Zhenhao; Qian, Dawei; Qian, Yefei; Guo, Jianming; Duan, Jin-Ao; Zhu, Min

    2014-07-15

    A highly sensitive and rapid ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) has been developed and validated for simultaneous quantification of seven components in rat plasma and five components in rat tissues after oral administration of the extracts of different combination Radix Angelicae Sinensis-Radix Paeoniae Alba herb couple and has been applied to compare the different pharmacokinetics and tissue distribution properties of these bioactive components. The extracts of Radix Angelicae Sinensis (RAS), Radix Paeoniae Alba (RPA) and Radix Angelicae Sinensis-Radix Paeoniae Alba herb couple (RRHC) were orally administrated to rats, respectively. The concentrations of ferulic acid, caffeic acid, vanillic acid, ligustilide, paeoniflorin, albiflorin and oxypaeoniflorin in rat plasma and the concentrations of ferulic acid, vanillic acid, paeoniflorin, albiflorin and oxypaeoniflorin in tissues were determined by UPLC-MS/MS. The plasma samples were pretreated by protein precipitation with methanol and the tissue samples were homogenated with water and pretreated by protein precipitation with methanol. Chromatographic separation was performed on a C18 column using 0.1% formic acid-acetonitrile as mobile phase for gradient elution. A triple quadrupole (TQ) tandem mass spectrometry equipped with an electrospray ionization source was used as detector operating both in positive and negative ionization mode and operated by multiple-reaction monitoring (MRM) scanning. Noncompartmental pharmacokinetic parameters were calculated by DAS 2.0 program. The differences between each group were compared by SPSS 16.0 with Independent-Samples T-test. The pharmacokinetic parameters (such as Cmax, Tmax, T1/2, AUC0-T, MRT0-T, Vz/F or CLz/F) of all the detected components between the single herb (RAS or RPA) and herb pair (RRHP) showed significant differences (P<0.05). It indicated that the compatibility of RAS and RPA could alter the pharmacokinetics features of each component. Tissue distribution results showed that ferulic acid, vanillic acid, paeoniflorin, albiflorin and oxypaeoniflorin mostly distributed in liver and kidney both in herb couple and single herb distributed most in liver and kidney. Compared with single herb, RRHC could increase or decrease the concentrations of five components at different time points compared with the sing herb. The results indicated the method was successfully applied to the comparative study on pharmacokinetics and tissue distribution of different combination of RRHC in rats. The compatibility of two Chinese herbs could alter the pharmacokinetics and tissue distribution properties of major bio-active components in the single herb. The results might be helpful for further investigation of compatibility mechanism of RRHC. PMID:24927419

  11. [The cDNA-AFLP differential display in developing anthers between cotton male sterile and fertile line of "Dong A"].

    PubMed

    Hou, Lei; Xiao, Yue-Hua; Li, Xian-Bi; Wang, Wen-Feng; Luo, Xiao-Ying; Pei, Yan

    2002-04-01

    cDNA-AFLP, an effective method for mRNA differential display, was employed to compare the gene expression in developing anthers between the male sterile and fertile plants of cotton (Gossypium hirsutum L.) cultivar, Dong A. In the micro-spore stage, there were more differential bands of cDNA-AFLP than that in the meio-phase stage. Among 64 differential fragments produced by cDNA-AFLP, three were randomly selected for further analysis. RNA dot blotting showed that the GHA27 transcript was expressed mainly in floral tissues; on the other hand, the GHA28 and GHA47 transcripts were present specifically in anther. BLAST analysis demonstrated that GHA27 was highly similar to the plant ADP-ribosylation factor genes, while GHA28 and GHA27 were shown no significant similar to any sequences in the available databases. PMID:11985272

  12. Pleistocene macrotidal tide-dominated estuary delta succession, along the Dong Nai River, southern Vietnam

    NASA Astrophysics Data System (ADS)

    Kitazawa, T.

    2007-01-01

    This paper focuses on the facies and sequence stratigraphic interpretation of a tide-dominated incised-valley system that is rare among geological records of the world for its completeness. The subject is the Middle-Upper Pleistocene Ba Mieu and Thu Duc formations exposed along the Dong Nai River, southern Vietnam. Both the Ba Mieu and the Thu Duc formations are interpreted as a transgressive tide-dominated estuary succession overlain by a highstand tide-dominated delta succession. The tide-dominated estuary succession is generalized as follows, in ascending order: fluvial facies in landward portions, tidal flat, upward-coarsening and -thickening succession of marine sands with a tidal ravinement surface (TRS; created by tidal scouring during transgression) at the base, and subtidal lag in seaward portions. This tide-dominated estuary is distinguished from wave-dominated and wave- and tide-dominated estuaries by (1) the lack of a central basin (lagoon), tidal delta, or bayhead delta facies; (2) the widespread presence of marine sands; (3) the presence of a subtidal lag; and (4) the presence of an upper-flow-regime sand flat facies. The tide-dominated delta succession is generalized as follows, in ascending order: upward-convex unit of marine sand and onlapping tidal flat deposits, a thick upward-fining succession of tidal flat-salt marsh deposits, and coarse fluvial deposits. This delta is distinguished from an estuary as follows. (1) It shows thick, regional, upward-fining successions indicating shallowing, whereas upward-coarsening successions indicating deepening are recognized in an estuary. A maximum flooding surface (MxFS) is recognized in the coarsest part of the succession, in marine sand and tidal flat deposits. (2) Fluvial processes dominate the sediment supply, in contrast to an estuary, in which a thick marine sand body fed from marine sources is dominant. (3) Ebb tidal currents are dominant, whereas flood tidal currents are dominant in an estuary. Key features of the incised-valley system are (1) amplification of the incised-valley geometry by tidal ravinement erosion; (2) development of tidal channels filled with mud clasts in the estuary; (3) a thick marine sand body in the estuary; and (4) upward-convex unit of marine sand and a thick tidal flat-fluvial succession in the delta. The Ba Mieu Formation is recognized as depositional sequence (SQ) 1 between sequence boundary (SB) 1 below and SB2 above. SQ1 consists of transgressive systems tract (TST) 1 and highstand systems tract (HST) 1. SQ1 was formed by a transgression-regression cycle during marine isotope stage (MIS) 7. SB2 was formed by fluvial incision during the MIS 6 lowstand and is amalgamated with the TRS of MIS 5. The Thu Duc Formation is recognized as SQ2 between SB2 below and SB3 above, and it consists of TST2 and HST2. SQ2 was formed by a major transgression-regression cycle on which a lower-rank cyclicity was superposed during MIS 5. TST2 thins seaward as a result of tidal ravinement erosion. The landward extent of marine environment in MIS 5 is inferred to have been of greater scale than that in MIS 7 from the distribution of the facies and the TRS.

  13. A comparison of the chemical composition and bioactive ingredients of the Chinese medicinal mushroom DongChongXiaCao, its counterfeit and mimic, and fermented mycelium of Cordyceps sinensis

    Microsoft Academic Search

    Tai-Hao Hsu; Li-Hua Shiao; Chienyan Hsieh; Der-Ming Chang

    2002-01-01

    The Chinese herbal drug DongChongXiaCao, a medicinal and edible mushroom originating from the fungus Cordyceps sp., has been developed into health foods. Counterfeit and mimic types are frequently found in markets. Mycelial preparations of Cordyceps sinensis, via submerged fermentation, have been commercialized and also named DongChongXiaCao. This investigation endeavours to characterize the proximate composition, amino acid profiles, and contents of

  14. Ethyl acetate extract from Angelica Dahuricae Radix inhibits lipopolysaccharide-induced production of nitric oxide, prostaglandin E2 and tumor necrosis factor-alphavia mitogen-activated protein kinases and nuclear factor-kappaB in macrophages.

    PubMed

    Kang, Ok-Hwa; Lee, Go-Hoon; Choi, Hyuk Joon; Park, Pil Sang; Chae, Hee-Sung; Jeong, Seung-Il; Kim, Youn-Chul; Sohn, Dong Hwan; Park, Hyun; Lee, John Hwa; Kwon, Dong-Yeul

    2007-04-01

    Angelica dahurica (Umbelliferae) has been used to treat headache of common cold, supraorbital neuralgia, painful swelling on the body, nasal stuffiness, leukorrhea and arthralgia due to wind-dampness in Korean traditional medicine. It is also claimed to be effective in the treatment of acne, erythema, headache, toothache, sinusitis, colds and flu. The present study focused whether the ethyl acetate extract from Angelica Dahuricae Radix (EAAD) inhibits production of nitric oxide (NO), prostaglandin E(2) (PGE(2)) and tumor necrosis factor (TNF)-alpha, as well as expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), nuclear factor-kappaB (NF-kappaB) and mitogen-activated protein kinases (MAPKs) in lipopolysaccharide (LPS)-stimulated macrophages. EAAD inhibited LPS-induced NO, PGE(2) and TNF-alpha production as well as expression of iNOS and COX-2 in RAW 264.7 cells. EAAD inhibited LPS-induced TNF-alpha production in THP-1 cells. Furthermore, EAAD suppressed LPS-induced phosphorylation of p38 MAPK and extracellular-signal regulated kinases 1/2 (ERK1/2), I-kappaBalpha degradation, and NF-kappaB activation in RAW 264.7 cells. These results suggest that EAAD has the inhibitory effects on LPS-induced TNF-alpha, NO and PGE(2) production, and expression of iNOS and COX-2 in macrophage through blockade in the phosphorylation of MAPKs, following I-kappaBalpha degradation and NF-kappaB activation. PMID:17229575

  15. Effect of “Jian-Pi-Zhi-Dong Decoction” on Gamma-Aminobutyric Acid in a Mouse Model of Tourette Syndrome

    PubMed Central

    Zhang, Wen; Yu, Wenjing; Wei, Li; Lee, Minkyoung; Wang, Sumei

    2014-01-01

    The purpose of this study was to explore the positive effects of Jian-Pi-Zhi-Dong Decoction (JPZDD) on Tourette syndrome (TS) by investigating the expression of gamma-aminobutyric acid (GABA) and its type A receptor (GABAAR) in the striatum of a TS mice model. The model was induced by 3,3?-iminodipropionitrile (IDPN) treatment; then mice were divided into 4 groups (n=22, each); control and IDPN groups were gavaged with saline and the remaining 2 groups were gavaged with tiapride and JPZDD. We recorded the stereotypic behaviors of TS mice and measured the content of GABA in striatum by HPLC and GABAAR expression by immunohistochemistry and real-time PCR. Our results showed that JPZDD inhibited the abnormal behaviors of TS model mice and decreased GABA levels and GABAAR protein and mRNA expression in the striatum of TS model mice. In brief, the mechanism by which JPZDD alleviates TS symptoms may be associated with GABAAR expression downregulation in striatum which may regulate GABA metabolism. PMID:24812567

  16. Antitussive principles of Glycyrrhizae radix, a main component of the Kampo preparations Bakumondo-to (Mai-men-dong-tang).

    PubMed

    Kamei, Junzo; Nakamura, Rie; Ichiki, Hiroyuki; Kubo, Masayoshi

    2003-05-23

    We attempted to elucidate the antitussive principles of Glycyrrhizae radix, a main component of Bakumondo-to (Mai-men-dong-tang). Although the 50% methanol-eluted fraction (100 mg/kg, p.o.) caused a more than 60% reduction in the number of capsaicin-induced coughs, neither the water-eluted nor 100% ethanol-eluted fractions of water extract of G. radix had antitussive effects. The water extract of G. radix contained high levels of liquiritin, liquiritin apioside, isoliquiritin, isoliquiritin apioside and glycyrrhizin. On the other hand, the 50% methanol-eluted fraction contained mainly liquiritin and liquiritin apioside, but not the other compounds. Liquiritin apioside (3-30 mg/kg, p.o.), but not liquiritin, isoliquiritin, isoliquiritin apioside or glycyrrhizin, dose-dependently inhibited the number of coughs. Methysergide, a serotonin receptor antagonist, antagonized the antitussive effect of liquiritin apioside. However, the antitussive effect of liquiritin apioside was not antagonized by naloxone. Pretreatment with glibenclamide (3 mg/kg, i.p.), an ATP-sensitive potassium channel blocker, also significantly reduced the antinociceptive effect of liquiritin apioside. These results suggest that G. radix contains a potent antitussive compound, liquilitin apioside, whose antitussive effect may depend on both peripheral and central mechanisms. PMID:12782198

  17. Stratigraphy and optically stimulated luminescence (OSL) dating of a Quaternary sequence along the Dong Nai River, southern Vietnam

    NASA Astrophysics Data System (ADS)

    Kitazawa, Toshiyuki; Nakagawa, Takahiro; Hashimoto, Tetsuo; Tateishi, Masaaki

    2006-10-01

    The pre-Holocene Cenozoic sequence outcrops in the terrestrial part of the eastern margin of the Mekong Basin. However, the stratigraphy of the sequence is still unclear. Its detailed stratigraphy and chronology were therefore studied along the Dong Nai River, southern Vietnam, and the lithofacies and the relations among the formations were investigated from the outcrops. The ages of the deposits were determined by using optically stimulated luminescence (OSL) dating. The Ba Mieu Formation was deposited about 176±52 ka during marine isotope stage (MIS) 7-6. The Thu Duc Formation was deposited about 97±27 ka during MIS 5. Both the Ba Mieu and Thu Duc formations are composed of fluvial and tidally influenced coastal deposits. The newly proposed Nhon Trach Formation was originally an eolian (blanket) deposit, but it has been partly reworked by fluvial processes. The Nhon Trach Formation was deposited about 10.9±4.7 ka, in the last part of the Pleistocene to the beginning of the Holocene. The OSL ages for the Ba Mieu, Thu Duc, and Nhon Trach formations are younger than the ages previously assigned to these formations.

  18. Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome.

    PubMed

    Zhang, Wen; Yu, Wenjing; Wang, Daohan; Wei, Li; Lee, Minkyoung; Wang, Sumei

    2014-01-01

    The purpose of this study was to explore the positive effects of Jian-Pi-Zhi-Dong Decoction (JPZDD) on Tourette syndrome (TS) by investigating the expression of gamma-aminobutyric acid (GABA) and its type A receptor (GABAAR) in the striatum of a TS mice model. The model was induced by 3,3'-iminodipropionitrile (IDPN) treatment; then mice were divided into 4 groups (n=22, each); control and IDPN groups were gavaged with saline and the remaining 2 groups were gavaged with tiapride and JPZDD. We recorded the stereotypic behaviors of TS mice and measured the content of GABA in striatum by HPLC and GABAAR expression by immunohistochemistry and real-time PCR. Our results showed that JPZDD inhibited the abnormal behaviors of TS model mice and decreased GABA levels and GABAAR protein and mRNA expression in the striatum of TS model mice. In brief, the mechanism by which JPZDD alleviates TS symptoms may be associated with GABAAR expression downregulation in striatum which may regulate GABA metabolism. PMID:24812567

  19. Association between Gene Polymorphisms of Seven Newly Identified Loci and Type 2 Diabetes and the Correlate Quantitative Traits in Chinese Dong Populations

    PubMed Central

    LIU, Liya; CHEN, Lizhang; LI, Zhanzhan; LI, Liang; QU, Jian; XUE, Jing

    2014-01-01

    Abstract Background There are much heterogeneity in the genetic variation of type 2 diabetes (T2D). The purpose of this study was to investigate the association of seven novel genetic loci identified in a recent genome-wide association studies (GWAS) with T2D in Chinese Dong populations. Methods A case-controlled study was performed in individuals of Chinese Dong nationality. The genotypes of PARD3B (rs849230), LOC729993 (rs149228), EPHA4 (rs16862811), HNT (rs3099797), PTPRD (rs17584499 and rs649891), TOMM7 (rs2240727) genes were determined using Multiplex PCR-SNaPshot. The independent association between each polymorphism and T2D was assessed using unconditional binary logistic regression analysis (BLR). Results A total of 136 cases of T2D and 136 control subjects were enrolled in the study. The polymorphism of rs2240727 in TOMM7 gene was associated with T2D (odds ratio (OR) = 1.65, per copy of the risk T allele, P = 0.004). In addition, CT and TT were risk genotypes for T2D (OR (95% CIs):2.64 (1.28-5.45) and 3.42 (1.58-7.41) respectively). After correcting for multiple testing, the above results remained significant (all P < 0.05). After adjusting for the confounders of age, gender, and BMI, the association between T2D and rs2240727 remained significant (P < 0.01). There were significantly statistical difference in levels of fasting plasm glucose(FPG) among genotypes of rs2240727 in controls and patients, the levels of FPG were significantly higher in CT and TT genotypes than in CC genotype in both groups (all P < 0.05). Conclusions The rs2240727 genetic variant in TOMM7 was associated with T2D of Chinese Dong individuals, and might enhance the risk of T2D by affecting the level of FPG.

  20. Ultra high performance liquid chromatography with photodiode array detector and quadrupole time-of-flight tandem mass spectrometry coupled with discriminant analysis to evaluate Angelicae pubescentis radix from different regions.

    PubMed

    Ge, Ai-Hua; Ma, Wen-Fang; Wang, Chun-Peng; Li, Jin; He, Jun; Liu, Er-Wei; Adelakum, Tiwalade Adegoke; Zhang, Bo-Li; Gao, Xiumei; Chang, Yan-Xu

    2014-09-01

    A rapid and effective method was developed for the qualitative and quantitative analysis of the major chemical constituents in Angelicae pubescentis radix by ultra high performance liquid chromatography with photodiode array detection and quadrupole time-of-flight tandem mass spectrometry. The chromatographic separation was achieved on an ACQUITY UHPLC BEH C18 column (2.1 × 100 mm, 1.7 ?m). Nine phenolic acids, 30 coumarins, bisabolangelone, and adenosine were identified by quadrupole time-of-flight tandem mass spectrometry. All calibration curves exhibited good linearity (r > 0.9996) within the linear ranges. The relative standard deviation calculated for intraday and interday precision, stability, and accuracy were <5%. The mean recovery ranged from 95.8 to 106%. The overall limits of detection and quantification were 0.025-0.160 and 0.100-0.560 ?g/mL, respectively. Discriminant analysis was investigated as a method for evaluating the quality of the samples with 100% correction in their classification. The results demonstrated that the developed method could successfully be used to differentiate samples from different regions and could be a helpful tool for detection and confirmation of the quality of traditional Chinese medicines. PMID:25044521

  1. Tracing metal sources in core sediments of the artificial lake An-Dong, Korea: Concentration and metal association.

    PubMed

    Choi, Mansik; Park, Jongkyu; Cho, Dongjin; Jang, Dongjun; Kim, Miseon; Choi, Jongwoo

    2015-09-15

    The concentration and source of trace metals in the artificial lake An-Dong, which has widespread abandoned mines and a Zn smelter upstream of the drainage basin, were investigated. Soils (18ea), stream waters (15ea) and sediments (15ea) in the main channel and five tributaries downstream of the Zn smelter towards the lake (~50km downstream) were collected. And two core sediments were also taken from the middle of the lake. All samples were analyzed for trace metals in bulk and in a 1N HCl-leached fraction. Although the soil and stream sediments consisted mostly of sand-sized grains, concentrations of metals (Cu, Zn, Cd and Pb) were very high in all samples, including soils, stream waters and sediments at sites near the Zn smelter. However the metal concentrations decreased rapidly downstream, suggesting that the area of impact of the smelter lies within 5km. Highly enriched metal concentrations were also found in dated core sediments from the lake; while the highest concentrations of Co, Ni, As, Cu, Zn, Cd and Pb were detected in the bottom of the sediment core (dated 1980) they decreased towards 2000, and only Cu, Zn and Cd concentrations increased again in present-day samples. Since the temporal variation in metal concentrations appeared consistent with historical variation in ore mining and Zn smelter production rates, a model combining the production rates of each was developed, which estimated 3%, 12% and 7% contributions from Zn smelter compared to ore mining production rate to levels of Cu, Cd and Zn, respectively, suggesting the different pathways by different sources. In addition, analysis of Cd/Zn and Cu/Zn ratios showed that contamination from ore mining decreased from 1980 to 2000, and smelting processes were most likely responsible for metal enrichment (Cu, Cd and Zn) from 2000 to the present. PMID:25981937

  2. HLA polymorphism of the Zhuang population reflects the common HLA characteristics among Zhuang-Dong language-speaking populations*

    PubMed Central

    Shi, Li; Huang, Xiao-qin; Shi, Lei; Tao, Yu-fen; Yao, Yu-feng; Yu, Liang; Lin, Ke-qin; Yi, Wen; Sun, Hao; Tokunaga, Katsushi; Chu, Jia-you

    2011-01-01

    A study of the human leukocyte antigen (HLA) genetic characteristics in the Zhuang, the largest ethnic population in China, would provide insight into Zhuang history and give a useful tool for disease associations, transplantation, and anthropology. In the present study, we report the comprehensive HLA-A, HLA-B, HLA-C, and HLA-DRB1 alleles and haplotypes in the Zhuang population of southern China for the first time. A total of 13 HLA-A, 24 HLA-B, 22 HLA-C, and 18 HLA-DRB1 were identified in 104 Zhuang individuals. The frequencies of HLA-A*11:01, A*02:07, A*24:02, A*02:03, and A*33:03 on A loci, B*15:02, B*58:01, B*46:01, and B*13:01 on B loci, C*03:04, C*08:01, C*01:02, C*03:02, and C*07:02 on C loci, and DRB1*15:01, DRB1*16:02, DRB1*14:01, DRB1*15:02, and DRB1*03:01 on the DRB1 loci were >10%. The A*33:03-C*03:02-B*58:01-DRB1*03:01 and A*02:07-C*01:02-B*46:01-DRB1*14:01 haplotypes were predominant in the Zhuang. The phylogenetic tree, as well as the analysis of haplotypes, suggested that the Zhuang are genetically similar to southern Chinese populations, especially the Zhuang-Dong language-speaking populations, such as the Bouyei, Dai, and Maonan. Even though the Zhuang and southern Chinese populations shared common alleles and haplotypes, the Zhuang has maintained its unique genetic characteristics. PMID:21634035

  3. Persistent organic pollutants in sediments from Sai Gon-Dong Nai River basin, Vietnam: levels and temporal trends.

    PubMed

    Minh, Nguyen Hung; Minh, Tu Binh; Iwata, Hisato; Kajiwara, Natsuko; Kunisue, Tatsuya; Takahashi, Shin; Viet, Pham Hung; Tuyen, Bui Cach; Tanabe, Shinsuke

    2007-05-01

    Surficial sediment samples were collected from Hochiminh City canals, the Sai Gon-Dong Nai River, and its estuary, one of the most predominant industrial areas in Hochiminh City, southern Vietnam, for determination of selected persistent organic pollutants (POPs). Contamination pattern was as follows: PCBs > or = DDTs > HCB > CHLs > HCHs. Concentrations of PCBs and DDTs ranged from 0.50-150 ng/g and 0.15-72 ng/g dry wt, respectively. On the other hand, concentrations of CHLs, HCHs, and HCB were mostly <2 ng/g dry wt. Levels of the all organochlorines (OCs) in Hochiminh City canals were significantly higher than those in the other areas, indicating the urban areas as major pollution sources to the aquatic environment. The contamination pattern was PCBs > DDTs in the city canals but PCBs < DDTs in the downstream and the estuary, suggesting particularly high contamination by PCBs in the city. Examination of DDTs composition and their ratios demonstrated continuous input of this pesticide to the city canals. However, the combination of our data and those from available literature implies a decreasing trend of PCBs and DDTs in the environment. DDTs concentrations have been reduced 50% after approximately 5 years. Composition of CHLs in the sediment from Hochiminh City canals was comparable to those of common technical mixtures, suggesting continuous input of CHLs to the environment. CHLs might be in use for purposes like termite control, wood preservation, and protection of underground cables. Hazard assessment implies high toxic potential of DDTs for sediments from Hochiminh City canals and suggests the need for better management of municipal discharges. PMID:17354037

  4. Association between Apolipoprotein E Polymorphism and Chronic Kidney Disease in the Korean General Population: Dong-gu Study

    PubMed Central

    Choi, Seong-Woo; Kweon, Sun-Seog; Choi, Jin-Su; Rhee, Jung-Ae; Lee, Young-Hoon; Nam, Hae-Sung; Jeong, Seul-Ki; Park, Kyeong-Soo; Ryu, So-Yeon; Kim, Hee Nam; Song, Hye-Rim

    2014-01-01

    Background Few studies have investigated the association between Apolipoprotein E (APOE) polymorphisms and chronic kidney disease (CKD) in the general population, and their results are inconsistent. Methods The current study population was composed of 9,033 subjects aged ? 50 years who participated in the baseline survey of the Dong-gu Study, which was conducted in Korea between 2007 and 2010. APOE polymorphisms were identified by polymerase chain reaction, and the estimated glomerular filtration rate (eGFR) was calculated using the Modification of Diet in Renal Disease equation. Results Individuals with the APOE E2 allele had significantly lower total and low density lipoprotein cholesterol levels, those with the APOE E4 allele had lower high density lipoprotein (HDL) cholesterol levels, and those with the APOE E3 allele had lower log-triglyceride levels. Adjusting for covariates (sex, age, body mass index, smoking, systolic blood pressure, hypertension, diabetes, total cholesterol, HDL cholesterol, log-transformed triglycerides, and log-transformed albumin to creatinine ratio), mean eGFR was not significantly different among APOE alleles (E2, 69.4 mL/min/1.73 m2; E3, 69.5 mL/min/1.73 m2; E4, 69.4 ml/min/1.73 m2; P = 0.873). Additionally, the odds ratios (ORs) indicated that APOE polymorphisms were not independent risk factors for CKD (OR, 1.07; 95% confidence interval [CI], 0.91 to 1.26 for the E2 vs. E3 allele; OR, 1.01; 95% CI, 0.88 to 1.16 for the E4 vs. E3 allele). Conclusion APOE polymorphisms were not associated with either eGFR or CKD in the general Korean population. PMID:25426275

  5. HLA polymorphism of the Zhuang population reflects the common HLA characteristics among Zhuang-Dong language-speaking populations.

    PubMed

    Shi, Li; Huang, Xiao-qin; Shi, Lei; Tao, Yu-fen; Yao, Yu-feng; Yu, Liang; Lin, Ke-qin; Yi, Wen; Sun, Hao; Tokunaga, Katsushi; Chu, Jia-you

    2011-06-01

    A study of the human leukocyte antigen (HLA) genetic characteristics in the Zhuang, the largest ethnic population in China, would provide insight into Zhuang history and give a useful tool for disease associations, transplantation, and anthropology. In the present study, we report the comprehensive HLA-A, HLA-B, HLA-C, and HLA-DRB1 alleles and haplotypes in the Zhuang population of southern China for the first time. A total of 13 HLA-A, 24 HLA-B, 22 HLA-C, and 18 HLA-DRB1 were identified in 104 Zhuang individuals. The frequencies of HLA-A*11:01, A*02:07, A*24:02, A*02:03, and A*33:03 on A loci, B*15:02, B*58:01, B*46:01, and B*13:01 on B loci, C*03:04, C*08:01, C*01:02, C*03:02, and C*07:02 on C loci, and DRB1*15:01, DRB1*16:02, DRB1*14:01, DRB1*15:02, and DRB1*03:01 on the DRB1 loci were >10%. The A*33:03-C*03:02-B*58:01-DRB1*03:01 and A*02:07-C*01:02-B*46:01-DRB1*14:01 haplotypes were predominant in the Zhuang. The phylogenetic tree, as well as the analysis of haplotypes, suggested that the Zhuang are genetically similar to southern Chinese populations, especially the Zhuang-Dong language-speaking populations, such as the Bouyei, Dai, and Maonan. Even though the Zhuang and southern Chinese populations shared common alleles and haplotypes, the Zhuang has maintained its unique genetic characteristics. PMID:21634035

  6. Petroleum potential of Oligocene lacustrine mudstones and coals at Dong Ho, Vietnam — an outcrop analogue to terrestrial source rocks in the greater Song Hong Basin

    NASA Astrophysics Data System (ADS)

    Petersen, H. I.; Andersen, C.; Anh, P. H.; Bojesen-Koefoed, J. A.; Nielsen, L. H.; Nytoft, H. P.; Rosenberg, P.; Thanh, L.

    2001-02-01

    The outcrop of Oligocene age at Dong Ho, northern Vietnam, may constitute an immature analogue to offshore terrestrial source rocks in the greater Song Hong Basin. The outcrop includes an interval with two source rocks: (1) highly oil-prone carbonaceous mudstones containing kerogen types IIA and IIA/I, and with TOC contents from 6.48 to 16.89 wt%, and HI values from 472 to 690; and (2) oil-prone humic coals (kerogen type III) with HI values from 200 to 242. The mudstones were deposited in oxygen-deficient lakes, which on occasion were subject to marine influence, and the coals accumulated in freshwater peat-forming mires. The coals have broad activation energy ( Ea) distributions, while the mudstones have Ea distributions characterised by a pronounced principal Ea. During artificial maturation about 16-17% of the organic carbon in the coals and 45-50% of the organic carbon in the mudstones participated in petroleum formation. The two source rocks primary generate oil and secondary generate gas, however, the mudstones realised the majority of their potential over a more narrow temperature range than the coals. The excellent generative potential of the terrestrial source rocks at Dong Ho is encouraging for offshore exploration for reservoirs charged by Cenozoic rift-lake successions.

  7. Association between methylenetetrahydrofolate reductase C677T polymorphism and bone mineral density: the Dong-gu Study and the Namwon Study.

    PubMed

    Shin, Min-Ho; Choi, Jin-Su; Rhee, Jung-Ae; Lee, Young-Hoon; Nam, Hae-Sung; Jeong, Seul-Ki; Park, Kyeong-Soo; Kim, Hye-Yeon; Ryu, So-Yeon; Choi, Seong-Woo; Song, Hye-Rim; Kim, Hee Nam; Cauley, Jane A; Kweon, Sun-Seog

    2013-06-01

    The purpose of this study was to examine the association between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and bone mineral density (BMD). Two large cohort studies were performed: the Dong-gu Study (3,621 men and 5,409 women) and the Namwon Study (3,703 men and 5,672 women). We assessed lumbar spine and femoral neck BMD by dual-energy X-ray absorptiometry. Genotypes were determined by real-time polymerase chain reaction. Multiple linear regression analysis was performed to evaluate the association between MTHFR C677T and BMD, adjusting for age, weight and height. The MTHFR C677T genotype frequencies for CC, CT, and TT genotypes were 34.5, 48.7, and 16.8%, respectively, in the Dong-gu Study and 33.6, 49.2, and 17.2%, respectively, in the Namwon Study. There are no significant differences between the MTHFR C677T genotype and the BMD at the lumbar spine and femoral neck in men or women in both cohorts. PMID:23772168

  8. Association between Methylenetetrahydrofolate Reductase C677T Polymorphism and Bone Mineral Density: The Dong-gu Study and the Namwon Study

    PubMed Central

    Shin, Min-Ho; Choi, Jin-Su; Rhee, Jung-Ae; Lee, Young-Hoon; Nam, Hae-Sung; Jeong, Seul-Ki; Park, Kyeong-Soo; Kim, Hye-Yeon; Ryu, So-Yeon; Choi, Seong-Woo; Song, Hye-Rim; Kim, Hee Nam; Cauley, Jane A.

    2013-01-01

    The purpose of this study was to examine the association between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and bone mineral density (BMD). Two large cohort studies were performed: the Dong-gu Study (3,621 men and 5,409 women) and the Namwon Study (3,703 men and 5,672 women). We assessed lumbar spine and femoral neck BMD by dual-energy X-ray absorptiometry. Genotypes were determined by real-time polymerase chain reaction. Multiple linear regression analysis was performed to evaluate the association between MTHFR C677T and BMD, adjusting for age, weight and height. The MTHFR C677T genotype frequencies for CC, CT, and TT genotypes were 34.5, 48.7, and 16.8%, respectively, in the Dong-gu Study and 33.6, 49.2, and 17.2%, respectively, in the Namwon Study. There are no significant differences between the MTHFR C677T genotype and the BMD at the lumbar spine and femoral neck in men or women in both cohorts. PMID:23772168

  9. [Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

    PubMed

    Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

    2014-05-01

    Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way. PMID:25208840

  10. APOE Polymorphism Is Associated with C-reactive Protein Levels but Not with White Blood Cell Count: Dong-gu Study and Namwon Study.

    PubMed

    Yun, Yong-Woon; Kweon, Sun-Seog; Choi, Jin-Su; Rhee, Jung-Ae; Lee, Young-Hoon; Nam, Hae-Sung; Jeong, Seul-Ki; Park, Kyeong-Soo; Ryu, So-Yeon; Choi, Seong-Woo; Kim, Hee Nam; Cauley, Jane A; Shin, Min-Ho

    2015-07-01

    We evaluated the association of the APOE polymorphism with serum C-reactive protein levels and white blood cell count in two large population-based studies in Korean. The datasets included the Dong-gu study (n = 8,893) and the Namwon Study (n = 10,032). APOE genotypes were identified by polymerase chain reaction-restriction fragment length polymorphism. Multivariable linear regression analysis was performed to evaluate the relationship of APOE genotypes with C-reactive protein levels and white blood cell count with adjustments for age, sex, body mass index, smoking, diabetes, hypertension, and serum lipids. In the multivariate model, carriers of E3E4 or E4E4 genotype had significantly lower C-reactive protein levels compared with carriers of E3E3 genotype group (0.50 mg/L vs. 0.67 mg/L; 0.37 mg/L vs. 0.67 mg/L, respectively, for the Dong-gu Study and 0.47 mg/L vs. 0.66 mg/L; 0.45 mg/L vs. 0.66 mg/L, respectively, for the Namwon Study). However, there was no difference in white blood cell count among APOE genotypes. We found that the APOE E4 allele is associated with lower C-reactive protein levels, but not white blood cell count. Our results suggest that APOE genotype may influence C-reactive protein levels through non-inflammatory pathway. PMID:26130946

  11. Dong, A., E. Fixler and A.M. Agogino, "A Case Study of Policy Decisions for Federated Search Across Digital Libraries," Proceedings of ICDL 2004 (International Conference on Digital Libraries), The

    E-print Network

    Agogino, Alice M.

    repositories in real-time with respect to user search requests. While the underlying technologies for federated Case Study of Policy Decisions for Federated Search Across Digital Libraries," Proceedings of ICDL 2004. A Case Study of Policy Decisions for Federated Search Across Digital Libraries Andy Dong University

  12. Disappearance of Sea Floor of the Paleo-asian Ocean: Geological Evidence from the Dong Ujimqin, Inner Mongolia, China

    NASA Astrophysics Data System (ADS)

    Zhou, Z.; Zhang, T.; Wang, B.; Yu, Y.

    2010-12-01

    It is well accepted that the Central Asian Orogenic Belt (CAOB) formed by the Paleozoic collision of the Siberia and the North China plates and the simultaneous closure of the Paleo-Asian Sea, but the location of the suture zone is still very debatable. Three proposed hypotheses of where the suture zone is are: Solonker-Sonid Zuoqi-Hegenshan, Ophiolite belt along Solonker-Xar Moron River, and the Main Mongolian Lineament in Mongolia. Our mapping, geochronology and geochemistry work in Dong Ujimqin (about 240 km to the NE of Hegan Shan) support the third hypothesis the best. Paleozoic stratigraphy in the research area was studied in detail. From Ordovician to middle Permian, local stratigraphy from bottom to top includes: Ordovician echinodermmeta fossil bearing crystalline limestone, sandstone and argillite; Middle Devonian coarse grained sandstone and argillite; Lower Middle Permian interlayerred sandstone and siltstone. There is an angular unconformity between the Middle Devonian and the overlying Permian strata. The Permian strata contain fossils of Cathaysia flora which include Cladophlebis sp.1,Cladophlebis sp. 2, Pterophyllum daihoense Kawasaki, Calamites suckowiiBrongniart, Sphenopteris sp., Cladophlebis nystroemii Halle, Cladophlebis ozakii Yabe et Oishi, Emplectopteris triangularis Halle, Lepidophylloides sp., Mariopteris hallei (Stockmans et Mathieu), Cladophlebis manchuica (Kawasaki). Structurally, Ordovian strata thrust over the Middle Devonian from NW to SE, and the Middle Devonian thrust over Upper Devonian from NW to SE too. The strike of the axial plane of the folds associated with the thrusts is NE. Two Carboniferous magmatic belts were discovered in the research area. U-Pb zircon geochronology using LA-ICP-MS gave ages of 325-326Ma and 298-311Ma for the North and South belts respectively. The magamatic activities moved from NW to SE. Whole rock, trace element and REE geochemistry tell us that all these magmatic rocks are of syn-collisional characteristics. The discovery of the Cathaysia flora fossils, the NW to SE thrust faults, the syn-collisional magmatic rocks plus the shift of magmatic activities from NW to SE all indicate that the sea floor of the Paleo-Asian Ocean must located somewhere to the north of our research area, which could be the proposed Main Mongolian Lineament area.

  13. The determinants of long-term care utilization and equity of access to care among older adults in Dong-Ku of Incheon Metropolitan city, South Korea.

    PubMed

    Park, J M

    2005-01-01

    Under the current health care system, around three percent of the elderly remain uninsured. Based on the 2003 Dong-Ku Health Status Survey and the Aday and Andersen Access Framework, the present study examined the social and behavioral determinants of long-term care utilization and the extent to which equity in the use of long-term care services for the elderly has been achieved. The results indicate that universal health insurance system has not yielded a fully equitable distribution of services. Type of coverage and resource availability do not remain predictors of long-term care utilization. The data suggest that a universal health insurance system exists in South Korea with significant access problems for the population without insurance. Access differences also arise from obstacles in expanding the scope and level of plan benefits due to financial disparity among insurers. Health policy reforms must continue to concentrate on extending insurance coverage to the uninsured and establishing long-term insurance system for the elderly. PMID:16425654

  14. Chinese Medicine Formula "Jian-Pi-Zhi-Dong Decoction" Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice.

    PubMed

    Wang, Dao-Han; Li, Wei; Liu, Xiao-Fang; Zhang, Jin-Ming; Wang, Su-Mei

    2013-01-01

    Jian-Pi-Zhi-Dong Decoction (JPZDD) is dedicated to the treatment for Tourette syndrome (TS) with the guidance of the theories of Traditional Chinese Medicine (TCM). This study aims to investigate the expression of dopamine transporter (DAT) in the striatum and stereotyped behavior of TS mice model by intervention of JPZDD. Mice were induced by 3,3'-iminodipropionitrile (IDPN, 350?mg kg(-1) day(-1), i.p.) for 7 days and divided into 4 groups (n = 20, each): control and IDPN groups were gavaged with saline and the remaining 2 groups with Tiapride (Tia, 50?mg kg(-1) day(-1)) and JPZDD (20?g kg(-1) day(-1)), respectively. The results showed that the scores of stereotyped behavior in IDPN+JPZDD group were significantly reduced. A noticeably increased (11)C-?-CFT binding at bilateral striatum was observed after administration of JPZDD versus that of IDPN or Tia. Immunohistochemistry and in situ hybridization studies manifested higher levels of DAT protein and mRNA in IDPN+JPZDD group. These findings not only demonstrated that JPZDD could effectively inhibit the abnormal behaviors of TS mice model, but also increase the level of DAT in striatum. Therefore, JPZDD could be one of potential treatments of patients with TS. PMID:23431337

  15. Effect of different drying methods on the quality of Angelicae Sinensis Radix evaluated through simultaneously determining four types of major bioactive components by high performance liquid chromatography photodiode array detector and ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry.

    PubMed

    Bai, Ying-Jia; Kong, Ming; Xu, Jin-Di; Zhang, Xiao-Lin; Zhou, Shan-Shan; Wang, Xiao-Ning; Liu, Li-Fang; Li, Song-Lin

    2014-06-01

    In the present study, the effect of drying methods on the quality of Angelicae Sinensis Radix (DG), was evaluated by newly developed high performance liquid chromatography photodiode array detector (HPLC-DAD) and ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS/MS). Ten major bioactive components including two phenolic acids, two hydroxyl phthalides, four alkyl phthalides and two phthalide dimers were selected as evaluation chemical markers and the newly-established method was qualitatively and quantitatively validated. DG slices and whole roots dried in shade, sun light, hot air, vacuum, microwave, far infrared ray and combination of microwave and far infrared ray as well as the fresh DG samples were determined by the established methods. DG slices dried in hot air kept the similar chemical composition to that of fresh DG, while DG whole roots dried in vacuum retained highest contents of the major components. Coniferyl ferulate and ligustilide degraded significantly in DG slices dried by microwave, far infrared ray and their combination. The influence of such chemical changes induced by different drying methods on the bioactivities of DG warrants further investigation, so that the optimal drying method can be obtained for the standardization of DG herb. PMID:24561333

  16. The chondroprotective effects of ferulic acid on hydrogen peroxide-stimulated chondrocytes: inhibition of hydrogen peroxide-induced pro-inflammatory cytokines and metalloproteinase gene expression at the mRNA level

    Microsoft Academic Search

    M. P. Chen; S. H. Yang; C. H. Chou; K. C. Yang; C. C. Wu; Y. H. Cheng; Feng-Huei Lin

    2010-01-01

    Objective  The objective of the study is to evaluate the effect of ferulic acid (FA), an antioxidant from the Chinese herb Dong-Gui [Chinese\\u000a angelica, Angelica sinensis (Oliv.) Diels], on the regulation of various genes in hydrogen peroxide-stimulated porcine chondrocytes at the mRNA level.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  The effect of FA and the effective concentration of FA on porcine chondrocytes was evaluated by the lactate

  17. Administration, Quai Maria-Belgia 18 CH 1800 Vevey

    E-print Network

    'azote par le procédé Anammox Encadrant externe : Michel Chammartin, Unité assainissement, tél. 0848 180 180 Anammox pour le traitement de l'azote au sein d'une station d'épuration moderne et plus spécifiquement

  18. Observation des influences du changement du couvert forestier sur le comportement hydrologique de grands bassins versants tropicaux a l'aide de la teledetection numerique: Cas du bassin versant de Dong Nai, Viet Nam

    NASA Astrophysics Data System (ADS)

    Pham, Trinh Hung

    Monitoring hydrological behavior of a large tropical watershed following a forest cover variation has an important role in water resource management planning as well as for forest sustainable management. Traditional methods in forest hydrology studies are Experimental watersheds, Upstream-downstream, Experimental plots, Statistical regional analysis and Watershed simulation. Those methodes have limitations for large watersheds concerning the monitoring time, the lack of input data especially about forest cover and the capacity of extrapolating results accurately in terms of large watersheds. Moreover, there is still currently a scientific debate in forest ecology on relation between water and forest. The reason of this problem comes from geographical differences in publication concerning study zones, experimental watershed size and applied methods. It gives differences in the conclusions on the influence of tropical forest cover change on the changes of outlet water and yet on the yearly runoff in terms of large watershed. In order to exceed the limitations of actual methods, to solve the difficulty of acquiring forest cover data and to have a better understanding of the relation between tropical forest cover change and hydrological behavior evolution of a large watershed, it is necessary to develop a new approach by using numeric remote sensing. We used the watershed of Dong Nai as a case study. Results show that a fusion between TM and ETM+ Landsat image series and hydro-meteorologic data allow us to observe and detect flooding trends and flooding peaks after an intensive forest cover change from 16% to 20%. Flooding frequency and flooding peaks have clearly decreased when there is an increase of the forest cover from 1983 to 1990. The influence of tropical forest cover on the hydrological behavior is varying with geographical locations of watershed. There is a significant relation between forest cover evolution and environmental facteurs as the runoff coefficient (R = 0,87) and the yearly precipitation (R = 0,93).

  19. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms.

    PubMed

    Liu, J; Burdette, J E; Xu, H; Gu, C; van Breemen, R B; Bhat, K P; Booth, N; Constantinou, A I; Pezzuto, J M; Fong, H H; Farnsworth, N R; Bolton, J L

    2001-05-01

    Eight botanical preparations that are commonly used for the treatment of menopausal symptoms were tested for estrogenic activity. Methanol extracts of red clover (Trifolium pratense L.), chasteberry (Vitex agnus-castus L.), and hops (Humulus lupulus L.) showed significant competitive binding to estrogen receptors alpha (ER alpha) and beta (ER beta). With cultured Ishikawa (endometrial) cells, red clover and hops exhibited estrogenic activity as indicated by induction of alkaline phosphatase (AP) activity and up-regulation of progesterone receptor (PR) mRNA. Chasteberry also stimulated PR expression, but no induction of AP activity was observed. In S30 breast cancer cells, pS2 (presenelin-2), another estrogen-inducible gene, was up-regulated in the presence of red clover, hops, and chasteberry. Interestingly, extracts of Asian ginseng (Panax ginseng C.A. Meyer) and North American ginseng (Panax quinquefolius L.) induced pS2 mRNA expression in S30 cells, but no significant ER binding affinity, AP induction, or PR expression was noted in Ishikawa cells. Dong quai [Angelica sinensis (Oliv.) Diels] and licorice (Glycyrrhiza glabra L.) showed only weak ER binding and PR and pS2 mRNA induction. Black cohosh [Cimicifuga racemosa (L.) Nutt.] showed no activity in any of the above in vitro assays. Bioassay-guided isolation utilizing ER competitive binding as a monitor and screening using ultrafiltration LC-MS revealed that genistein was the most active component of red clover. Consistent with this observation, genistein was found to be the most effective of four red clover isoflavones tested in the above in vitro assays. Therefore, estrogenic components of plant extracts can be identified using assays for estrogenic activity along with screening and identification of the active components using ultrafiltration LC-MS. These data suggest a potential use for some dietary supplements, ingested by human beings, in the treatment of menopausal symptoms. PMID:11368622

  20. Song 3, 'Dongzi dongdai dong Song'

    E-print Network

    Hu Qianma

    ” is a butter lamp. “Zongbala” is a carved square stone where food, liquor and tea are offered daily to ancestors and deities. “Zengdian bukua” is a bowl for burning the incense. “Zhishong gailie” is a cup for pouring alchol or tea during offering rituals...

  1. In vitro immunomodulatory effects of herbal products.

    PubMed

    Wilasrusmee, Chumpon; Siddiqui, Josephine; Bruch, David; Wilasrusmee, Skuntala; Kittur, Smita; Kittur, Dilip S

    2002-10-01

    Immunosuppressive drugs have been developed from natural products such as soil and fungi, which are also the sources of some commonly used herbal products. However, the effect of herbal products on immune response has not been investigated. Because these products can affect the host immune system they can induce either rejection or tolerance after a transplant procedure. To investigate the effects of ten commonly used herbal products on transplant-related immune function we performed in vitro lymphocyte proliferation tests using phytohemagglutinin, mixed lymphocyte culture (MLC) assay, and interleukin (IL)-2 and IL-10 production from MLC. Dong quai, ginseng, and milk thistle had nonspecific immunostimulatory effects on lymphocyte proliferation, whereas ginger and green tea had immunosuppressive effects. Dong quai and milk thistle increased alloresponsiveness in MLC, whereas ginger and tea decreased these responses. The immunostimulatory effects of dong quai and milk thistle were consistently seen in both cell-mediated immune response and nonspecific lymphoproliferation, whereas that of ginseng was not. The immunosuppressive effect of green tea and ginger were mediated through a decrease in IL-2 production, but the immunostimulatory effects of dong quai and milk thistle were not. We conclude that green tea, dong quai, ginseng, milk thistle, and ginger have effects on in vitro immune assays that may be relevant in transplantation in humans. PMID:12412711

  2. Herbal Products and Supplements

    MedlinePLUS

    ... cohosh, dong quai, and soy), saw palmetto, and St. John’s wort. How do I safely take herbal products and ... not work the way it should. For example, St. John’s wort reduces the amount of certain drugs absorbed by ...

  3. Polyacrylamide-treated kaolin: A fabric study Sungho Kim, Angelica M. Palomino

    E-print Network

    Palomino, Angelica M.

    is face-to-face association due to polymer bridging. A relationship is found between polymer mineral particle systems. Polymers with deliberately chosen characteristics, such as molecular mass development in a clay­polymer system, specifically kaolin­polyacrylamide systems over a wide range of solids

  4. Mechanisms of prostate cancer prevention by Korean Angelica | Division of Cancer Prevention

    Cancer.gov

    Skip to main content Division of Cancer Prevention Search form Search Main menu Home Major Programs Research Networks Map Alliance of Glycobiologists for Detection of Cancer Barrett's Esophagus Translational Research Network (BETRNet) Cancer Prevention

  5. POLAR: Instrument and Results Brian G. Keating*, Angelica de Oliveira-Costa1

    E-print Network

    Timbie, Peter

    of the cosmic microwave background radiation. URL http://cmb.physics.wise.edu/polar INTRODUCTION The 2.7K Cosmic Microwave Background (CMB) radiation is a vital probe of all modern cosmological theories. This radiation, performance, and results of a polarimeter used to make precision measure- ments of the 2.7 K cosmic microwave

  6. Effects of selenizing angelica polysaccharide and selenizing garlic polysaccharide on immune function of murine peritoneal macrophage.

    PubMed

    Gao, Zhenzhen; Liu, Kuanhui; Tian, Weijun; Wang, Hongchao; Liu, Zhenguang; Li, Youying; Li, Entao; Liu, Cui; Li, Xiuping; Hou, Ranran; Yue, Chanjuan; Wang, Deyun; Hu, Yuanliang

    2015-07-01

    The effects of two selenizing polysaccharides (sCAP2 and sGPS6) on immune function of murine peritoneal macrophages taking two non-selenizing polysaccharides (CAP and GPS) and modifier Na2SeO3 as control. In vitro test, the changes of selenizing polysaccharides, non-selenizing polysaccharides and Na2SeO3 on murine macrophages function were evaluated by phagocytosis and nitric oxide (NO) secretion tests. In vivo test, the mice were injected respectively with 0.2, 0.4 and 0.6mg of sCAP2, sGPS6, CAP and GPS, or Na2SeO3 80?g or normal saline 0.4mL. The peritoneal macrophages were collected and cultured to determine the contents of TNF-?, IL-6 and IL-10 in supernatants by enzyme-linked immunosorbent assay. The results showed that sCAP2 and sGPS6 could significantly promote the phagocytosis and secretion of NO and three cytokines of macrophages in comparison with CAP and GPS. sCAP2 possessed the strongest activity. This indicates that selenylation modification can further improve the immune-enhancing activity of polysaccharide, and sCAP2 could be as a new immunopotentiator. PMID:25962819

  7. A review of "A Concise Companion to Milton" by Angelica Duran, ed. 

    E-print Network

    Egan, James

    2007-01-01

    of nature often connected with the new science? (163). If Adam and Eve repeatedly demonstrate their harmony and continuity with other natural things, Satan and the fallen angels violate, exploit, and deny the spirituality of the material world. Milton...

  8. A review of "The Age of Milton and the Scientific Revolution" by Angelica Duran 

    E-print Network

    Berry, Boyd M.

    2007-01-01

    with God-head, with more strength to foil Thy enemie, nor so to overcome Satan. . . (12: 386-391, emphasis mine) Other evidence suggests that armed blows are repeatedly deferred and martial gear and ?force? are ridiculed both in book 6, in Samson...

  9. A review of "The Age of Milton and the Scientific Revolution" by Angelica Duran

    E-print Network

    Berry, Boyd M.

    2007-01-01

    . The relational paradigm that now dominates psychoanalytic theory in the United States has not been widely acknowledged or used by literary critics. The first phase of psychoanalytic criticism derived from Freud?s own inter- pretation of literary texts...

  10. GREEN CLOUD COMPUTING Edited by Jun-Dong Cho

    E-print Network

    Cho, Jun Dong

    . #12;Big Data Processing 8 = The Google File System (HDFS) + MapReduce (Simplified Data Processing on Large Cluster) www.apache.org Cloudera HortonWorks Open Source Platform #12;Big Data Processing - Data Scientist 1.Math/Statistics 2.Algorithm/Programming Skill 1.Data Mining : Mahout, R 2.Opinion Mining 3

  11. Introduction to STM induced Luminescence Zhen-Chao Dong

    E-print Network

    Wang, Wei Hua

    · Luminescence from metal-oxide-metal (MOM) tunnel junctions · Early studies of photon emission by STM 2. Experimental Techniques · Photon collection systems · Photon detection systems · Modes of measurements 3 models 4. Summary Contents #12;Scanning Tunneling Microscope (STM) Induced

  12. Digital Face Makeup by Example Dong Guo and Terence Sim

    E-print Network

    Sim, Terence

    of Singapore Singapore, 117417 {guodong,tsim}@comp.nus.edu.sg Abstract This paper introduces an approach and shadow, etc., follow on top of the powder. Consider this scenario: when a customer enters a beauty salon. Alternatively, one may try on makeup digitally by way of digital photography and with the help of photo edit

  13. DISS. ETH NO. 16907 Dong-Bin Huang

    E-print Network

    Richner, Heinz

    , it specifies and digitalizes a strategy with decision variables, and makes the multiple elements of a strategy with sequence and timing, as well as (iv) a tool for the decision makers to explore strategies for reaching Decision-Support #12;#12;DISS. ETH NO. 16907 A Discrete-Event Dynamic Systems Approach for Environmental

  14. Fluorescent Probes Q. Shao, Y. Zheng, X. Dong, K. Tang,

    E-print Network

    Xing, Bengang

    ) for specific labeling and screen- ing of antibiotic-resistant bacteria are presented. b- Resistant Bacteria Catching those bugs: A set of fast and sensitive probes (LRBL1­3; see struc- ture Reporter of b-Lactamase Activity for Fluorescent Imaging and Rapid Screening of Antibiotic-Resistant

  15. Behavioral Portfolio Choice: An Analytical Treatment Xue Dong He

    E-print Network

    Financial Engineering and Risk Management Conference, the 2008 Oxford Behavioural Finance Conference's Oxford Offsite Quant Forum, the 2007 Workshop on Mathematical Control Theory and Finance, the 2007 of Quantitative Finance, The University of Oxford. Email: . Nomura Centre for Mathematical

  16. Ding Dong School (Skits and Things): Teaching Performance Art.

    ERIC Educational Resources Information Center

    Clark, Laurie Beth

    2003-01-01

    Considers the relevance of a semester length curriculum in Performance for Art and Theatre students. Contends that art majors in performance classes learn to value more ephemeral content, to work with time, and to think explicitly about audience, while theatre majors have an opportunity to engage with original, personally expressive content and to…

  17. Smoke Detection in Video DongKeun Kim1

    E-print Network

    Wang, Yuan-Fang

    signs that a forest fire is incipient. Flames may not be visible to the monitoring camera if the flames methods often use color and motion information to detect smoke from digital images. [5, 6, 7] detect

  18. Towards Performing Arts Information As Linked Data? Patrick Le Boeuf, Bibliothque nationale de France, Quai Franois Mauriac, 75706 Paris

    E-print Network

    Paris-Sud XI, Université de

    since 2000. A few months after the congress, Tim Berners-Lee, James Hendler and Ora Lassila introduced the notion of `Semantic Web' in a seminal article published in 2001.3 In 2006, Tim Berners-Lee introduced

  19. Plasma Processing of Transition Metals for Water Oxidation Angelica Ottavianoa, Coleman X.Kronawitterb, Peng Zhaob, Bruce E. Koelb

    E-print Network

    Petta, Jason

    · Characterization of the Plasma source: · Measure current density of extracted ion beam by inserting a Faraday Cup with molecular drag pumps to ~ 10-6 Torr base pressure. Faraday Cup · Collects ions at sample location to measure

  20. Narrated Landscape as Counterweight to Perception of Placelessness in Contemporary Urban Landscape: Re-Visioning Place in Gwangbok-Dong and Nampo-Dong, Busan, South Korea

    ERIC Educational Resources Information Center

    Lee, Sungkyung

    2009-01-01

    Although the contemporary commercial urban landscape is often assessed as placeless, this research proposes that even these seemingly anonymous places are repositories of thriving community values and meanings. Seeking a more complex reading, this research extends the scope of analysis from physical space to human use in order to reveal the…

  1. Mining Frequency Content of Network Traffic for Intrusion Detection Mian Zhou and Sheau-Dong Lang

    E-print Network

    Lang, Sheau-Dong

    they infect the host systems. One approach to intrusion detection is to look for suspicious patterns consists of the header information and the packet payload. The packet header includes a rich amount of information including the arrival time, packet length, payload size, protocol, source and destination ports

  2. Comparison and Research on New Rural Community Management Patterns of Shan Dong Province

    NASA Astrophysics Data System (ADS)

    Fang, Lei; Zhang, Xiaomei

    Rural community is an important institutional innovation,which has important effect and edification to future new rural management.There are three new rural community management patterns in shandong province:divisions of the village community,many villages community and village merge community. This article not only introduce three models,but also compare them in four aspects: community scale, community management,infrastructure,resource utilization.Pointing out the strength and weakness of three models.Drawing a conclusion that village merge community is the active reaction for rural urbanization. And could be the important recommended breed.

  3. March/April 2012 391527-3342/12/$31.002012 IEEE Yuandan Dong

    E-print Network

    Anlage, Steven

    @ee.ucla.edu) are with the Electrical Engineering Department, 63-129 ENGR-IV, University of California at Los Angeles, Los Angeles, CA/left-handed (CRLH) structures [2], [7]. Strictly speaking, all the practical LH media actually falls under

  4. Fabricating Spatially-Varying Subsurface Scattering Yue Dong Jiaping Wang Fabio Pellacini Xin Tong Baining Guo

    E-print Network

    Rajamani, Sriram K.

    BSSRDFs using two hardware setups: a milling machine and a 3D printer. 1 Introduction Traditional printing 2 Layer 3 (a) Input BSSRDF (b) Layered material volume (c) Fabricated Material Volume Figure 1: Our system automatically generates a layered material volume for approximating a custom BSSRDF. (a

  5. Scale-free trees: The skeletons of complex networks Dong-Hee Kim,1

    E-print Network

    Jeong, Hawoong

    , biological, and communication systems [1,2]. The inhomogeneity of network structures is conveniently, such as the coauthorship networks in social sys- tems [3], the metabolic networks and protein interaction net- works to study the dynamics as well as the struc- tural properties of networks because of their applications

  6. Electronic States of Oxidized GaN(0001) Surfaces Y. Dong and R. M. Feenstra

    E-print Network

    Feenstra, Randall

    work [1-3]. These states donate electrons to the channel of the HFETs, giving rise to the two-dimensional of GaN grown by plasma-assisted molecular beam epitaxy are investigated by scanning tunneling microscopy) is performed with a double-pass cylindrical mirror analyzer at incident electron energy of 3 keV. Peak-to- peak

  7. A controlled biochemical release device with embedded nanofluidic Haifeng Yang, Wei Hong, and Liang Dong

    E-print Network

    Hong, Wei

    from first principles Appl. Phys. Lett. 100, 153117 (2012) Fe3O4-citrate-curcumin: Promising conjugates for superoxide scavenging, tumor suppression and cancer hyperthermia J. Appl. Phys. 111, 064702 (2012) Integrated

  8. Systematic analysis of group identification in stock markets Dong-Hee Kim* and Hawoong Jeong

    E-print Network

    Jeong, Hawoong

    between the random and nonrandom property of the correlations 7­11 , and the maximum likelihood clustering method was developed and applied to identify cluster struc- tures in stock markets 12 . Also, these studies have been extended to the applications to the portfolio optimization in real market 5

  9. Semantic Web for Extending and Linking Jin Song Dong, Jing Sun, and Hai Wang

    E-print Network

    Dong, Jin Song

    /VDM/Z are designed for modeling system data and states, while CSP/CCS/-calculus are designed for modeling system textual links among the models. Recently the Semantic Web Activity proposed the idea of having data specification techniques exist for modeling different aspects of soft- ware systems and it's difficult to find

  10. FPCNA: A Field Programmable Carbon Nanotube Array Chen Dong, Scott Chilstedt, and Deming Chen

    E-print Network

    Chen, Deming

    Circuits]: Types and Design Styles ­ Gate arrays, Advanced technologies; B.7.2 [Integrated Circuits and nanoswitches to build high performance FPGA circuits. Categories and Subject Descriptors B.7.1 [Integrated. Copyright 2009 ACM 978-1-60558-410-2/09/02...$5.00. Several nanomaterial-based programmable architectures

  11. How do we sell the hygiene message? With dollars, dong or excreta?

    PubMed

    Jensen, Peter Kjaer Mackie; Phuc, Pham Duc; West, Line Gram Knudsen

    2010-01-01

    In North and Central Vietnam it is common among farmers to use excreta from the family double vault composting latrine (DVC) as fertilizer in the fields. The official Vietnamese health guidelines stipulate a six-month period of composting before applying excreta to two of their three annual crops. However, farmers in this region cannot afford to follow these guidelines and this paper presents the reasons why.In their efforts to ensure optimal hygienic conditions, by providing a guideline, the Vietnamese health authorities have not put sufficient attention to the 'excreta economy' in relation to farmers' livelihoods. The free fertilizer in the household DVC represents a value of approximately US$ 15.5 per year--or the equivalent of 15 percent of the annual household income for the poorest 20 percent of farmers. For this reason, the economic benefits derived from free fertilizer outweigh the hygiene message for most Vietnamese farmers. Even at national level the excreta economy has an impact. If Vietnam were to replace human excreta with imported fertilizer, it would involve an extra national expenditure of at least US$ 83 million a year.In order to convince Vietnamese farmers to adopt different fertilizing methods when reusing human excreta, it is necessary for the Vietnamese health authorities to change their hygiene message. They need to replace their current health sector-specific approach with a holistic one that takes the premises of farmers' livelihoods into account. If they do not the hygiene message will simply be lost. PMID:20565820

  12. Establishing river basin organisations inVietnam: Red River, Dong Nai River and Lower Mekong Delta.

    PubMed

    Taylor, P; Wright, G

    2001-01-01

    River basin management is receiving considerable attention at present. Part of the debate, now occurring worldwide, concerns the nature of the organisations that are required to manage river basins successfully, and whether special-purpose river basin organisations (RBOs) are always necessary and in what circumstance they are likely to (i) add to the management of the water resources and (ii) be successful. The development of river basin management requires a number of important elements to be developed to a point where the river basin can be managed successfully. These include the relevant laws, the public and non-government institutions, the technical capabilities of the people, the understanding and motivation of people, and the technical capacity and systems, including information. A river basin organisation (or RBO) is taken to mean a special-purpose organisation charged with some part of the management of the water resources of a particular river basin. Generally speaking, such organisations are responsible for various functions related to the supply, distribution, protection and allocation of water, and their boundaries follow the watershed of the river in question. However, the same functions can be carried out by various organisations, which are not configured on the geographical boundaries of a river basin. This paper outlines recent work on river basin organisation in Vietnam, and makes some comparisons with the situation in Australia. PMID:11419135

  13. Qiang-Dong proper quantization rule and its applications to exactly solvable quantum systems

    NASA Astrophysics Data System (ADS)

    Serrano, F. A.; Gu, Xiao-Yan; Dong, Shi-Hai

    2010-08-01

    We propose proper quantization rule, ?x_Ax_B k(x)dx-?x0Ax0Bk0(x)dx=n?, where k(x )=?2M[E -V(x)] /?. The xA and xB are two turning points determined by E =V(x), and n is the number of the nodes of wave function ?(x ). We carry out the exact solutions of solvable quantum systems by this rule and find that the energy spectra of solvable systems can be determined only from its ground state energy. The previous complicated and tedious integral calculations involved in exact quantization rule are greatly simplified. The beauty and simplicity of the rule come from its meaning—whenever the number of the nodes of ?(x ) or the number of the nodes of the wave function ?(x ) increases by 1, the momentum integral ?xAxBk(x )dx will increase by ?. We apply this proper quantization rule to carry out solvable quantum systems such as the one-dimensional harmonic oscillator, the Morse potential and its generalization, the Hulthén potential, the Scarf II potential, the asymmetric trigonometric Rosen-Morse potential, the Pöschl-Teller type potentials, the Rosen-Morse potential, the Eckart potential, the harmonic oscillator in three dimensions, the hydrogen atom, and the Manning-Rosen potential in D dimensions.

  14. Effectiveness of lifesaving skills training and improving institutional emergency obstetric care readiness in Lam Dong, Vietnam.

    PubMed

    Sloan, Nancy L; Nguyen, Thi Nhu Ngoc; Do, Trong Hieu; Quimby, Charlotte; Winikoff, Beverly; Fassihian, Goli

    2005-01-01

    Essential obstetric care is promoted as the prime strategy to save women's lives in developing countries. We measured the effect of improving lifesaving skills (LSS) capacity in Vietnam, a country in which most women deliver in health facilities. A quasi-experimental study was implemented to assess the impact of LSS training and readiness (availability of essential obstetric equipment, supplies, and medication) on the diagnosis of life-threatening obstetric conditions and appropriate management of labor and birth. The intervention (LSS training and readiness) was provided to all clinics and hospitals from 1 of 3 demographically similar districts in southcentral Vietnam, to hospitals only in another district, with the third district serving as the comparison group. Detection of life-threatening obstetric conditions increased in both experimental clinics and hospitals, but the intervention only improved the management of these conditions in hospitals. Management of life-threatening obstetric conditions is most effective in hospitals. The intervention did not clearly benefit women delivering in clinics. PMID:15973269

  15. How do we sell the hygiene message? With dollars, dong or excreta?

    PubMed Central

    2010-01-01

    In North and Central Vietnam it is common among farmers to use excreta from the family double vault composting latrine (DVC) as fertilizer in the fields. The official Vietnamese health guidelines stipulate a six-month period of composting before applying excreta to two of their three annual crops. However, farmers in this region cannot afford to follow these guidelines and this paper presents the reasons why. In their efforts to ensure optimal hygienic conditions, by providing a guideline, the Vietnamese health authorities have not put sufficient attention to the ‘excreta economy’ in relation to farmers’ livelihoods. The free fertilizer in the household DVC represents a value of approximately US$ 15.5 per year - or the equivalent of 15 percent of the annual household income for the poorest 20 percent of farmers. For this reason, the economic benefits derived from free fertilizer outweigh the hygiene message for most Vietnamese farmers. Even at national level the excreta economy has an impact. If Vietnam were to replace human excreta with imported fertilizer, it would involve an extra national expenditure of at least US$ 83 million a year. In order to convince Vietnamese farmers to adopt different fertilizing methods when reusing human excreta, it is necessary for the Vietnamese health authorities to change their hygiene message. They need to replace their current health sector-specific approach with a holistic one that takes the premises of farmers' livelihoods into account. If they do not the hygiene message will simply be lost. PMID:20565820

  16. VizieR Online Data Catalog: HST/NICMOS Galactic Center survey catalogue (Dong+, 2011)

    NASA Astrophysics Data System (ADS)

    Dong, H.; Wang, Q. D.; Cotera, A.; Stolovy, S.; Morris, M. R.; Mauerhan, J.; Mills, E. A.; Schneider, G.; Calzetti, D.; Lang, C.

    2012-04-01

    Our Hubble Space Telescope/Near-Infrared Camera and Multi-Object Spectrometer (HST/NICMOS) Paschen ? survey of the Galactic Centre, first introduced by Wang et al. (2010MNRAS.402..895W), provides a uniform, panoramic, high-resolution map of stars and an ionized diffuse gas in the central 416arcmin2 of the Galaxy. This survey was carried out with 144 HST orbits using two narrow-band filters at 1.87 and 1.90um in NICMOS Camera 3. In this paper, we describe in detail the data reduction and mosaicking procedures followed, including background level matching and astrometric corrections. We have detected ~570000 near-infrared (near-IR) sources using the 'starfinder' software and are able to quantify photometric uncertainties of the detections. (3 data files).

  17. VizieR Online Data Catalog: Broad-line Balmer decrements in blue AGN (Dong+, 2008)

    NASA Astrophysics Data System (ADS)

    Dong, X.; Wang, T.; Wang, J.; Yuan, W.; Zhou, H.; Dai, H.; Zhang, K.

    2009-01-01

    We have investigated the broad-line Balmer decrements (H{alpha/H{beta}) for a large, homogeneous sample of Seyfert 1 galaxies and quasi-stellar objects (QSOs) using spectroscopic data obtained in the Sloan Digital Sky Survey. The sample, drawn from the Fourth Data Release, comprises 446 low-redshift (z<=0.35) active galactic nuclei (AGN) that have blue optical continua as indicated by the spectral slopes in order to minimize the effect of dust extinction. We find that (i) the distribution of the intrinsic broad-line H?/H{beta} ratio can be well described by log-Gaussian, with a peak at H?/H{beta}=3.06 and a standard deviation of about 0.03dex only; (ii) the Balmer decrement does not correlate with AGN properties such as luminosity, accretion rate and continuum slope, etc.; (iii) on average, the Balmer decrements are found to be only slightly larger in radio-loud sources (3.37) and sources having double-peaked emission-line profiles (3.27) compared to the rest of the sample. We therefore suggest that the broad-line H?/H{beta} ratio can be used as a good indicator for dust extinction in the AGN broad-line region; this is especially true for radio-quiet AGN with regular emission-line profiles, which constitute the vast majority of the AGN population. (2 data files).

  18. How to Continue the Beauty of Traditional Architecture of Dong Village ------the exploration of cultural protection

    NASA Astrophysics Data System (ADS)

    Wen, Fan; Xiaohua, Zhu

    Based on architectural culture of ethnic minority and folk customs, keep multiple characteristics of traditional architecture, inject new connotation, meet people's new demand of living condition. Explore a feasible approach to inherit traditional dwellings and diversify architecture. Ensure the healthy development of traditional architecture.

  19. Application of 3S Techniques in the Study of Wetland Environment of Dong Ting Lake

    NASA Astrophysics Data System (ADS)

    Xie, Baicheng; Zhang, Chunxia; Shuai, Xiqiang; Luo, Boliang

    Wetland is a multifunctional ecosystem in the earth, wetlands possess irreplaceable and enormous ecological functions and serve as an essential life supporting system. how to apply the new and high technology to the study of wetland has become the key point in wetland study area in our country. RS, GIS and GPS technology provide a new method for resource and ecological environment monitor. In this paper, the problem and development trend of 3S technology are discussed. Application of 3S technique in the study of wetland environment of Dongting Lake are described. The wetland monitor ways and technique route are introduced. The beach and water area information were gained.the dynamic changes of water were evaluated objective and quantitative. Finally, we point out the difficulties of wetland monitor of Dongting Lake.

  20. Fatigue of polymer-supported Ag thin films Gi-Dong Sim,a,b

    E-print Network

    applications such as paper-like electronic displays [1], thin-film solar cells [2], electrical sensors [3-Bok Leea and Joost J. Vlassakb, a Department of Mechanical Engineering, KAIST, 291 Daehak-ro, Yuseong. Once through-thickness cracks are formed in the metal layer, cracks propagate and the resistance

  1. Extended universality of the surface curvature in equilibrium crystal shapes Jae Dong Noh and Doochul Kim

    E-print Network

    Kim, Doochul

    beyond a critical value of the electric field. This transition is in the Pokrovsky- Talapov PT transition universality class 7,10 . The PT transition is characterized by the specific heat exponent 1/2 10 , which implies that the free energy scales as f h hc 3/2 . Equation 1 enables one to identify the ordered

  2. IMPROVING THE QUALITY OF DEPTH IMAGE BASED RENDERING FOR 3D VIDEO , Dong Tian

    E-print Network

    California at Santa Barbara, University of

    , simultaneous use of many views significantly increases the amount of raw data compared with 2D video or stereo systems is often estimated with passive computer vision techniques such as stereo rather than gener- ated captured from multiple calibrated cameras and their associated per-pixel depth information. Conceptually

  3. HANDLING OVERLAPS IN SPOKEN TERM DETECTION Dong Wang, Nicholas Evans, Raphael Troncy

    E-print Network

    Edinburgh, University of

    pragmatic approaches, e.g. choosing the best detec- tion to represent all the overlaps. In this paper we systems, overlap- ping detections are merged into a single detection by some pragmatic approach studies [7] that an ATWV-oriented decision strategy [8] is essential for OOV STD, however accumulated

  4. A Self-powered Wireless Sensor Node for Structural Health , Dong Sam Haa

    E-print Network

    Ha, Dong S.

    to harvest vibration energy using a piezoelectric cantilever. The circuit generates a regulated DC output from a piezoelectric generator, while matching the source impedance dynamically. The energy harvesting. The front end part is an energy harvesting system. A piezoelectric cantilever generates AC power

  5. A Data Placement Strategy in Scientific Cloud Workflows Dong Yuan, Yun Yang, Xiao Liu, Jinjun Chen

    E-print Network

    Yang, Yun

    , Melbourne, Australia 3122 {dyuan, yyang, xliu, jchen}@swin.edu.au ABSTRACT In scientific cloud workflows; cloud computing; 1. INTRODUCTION Running scientific workflow applications usually need not only high the world to use. The emergence of cloud computing technologies offers a new way to develop scientific

  6. X-RAY TAIL IN NGC 7619 Dong-Woo Kim,1

    E-print Network

    Kim, Dong-Woo

    or sloshing. The morphology of the structure is more in line with a ram pressure stripping phenomenon, while the position of NGC 7619 at the center of the Pegasus I group, and its dominance, would prefer sloshing this feature, Ascasibar & Markevitch (2006) introduced a new mechanism, called sloshing, which may explain

  7. Photolithography with transparent reflective photomasks* Dong Qin, Younan Xia, Andrew J. Black, and George M. Whitesidesa)

    E-print Network

    Prentiss, Mara

    by casting a prepolymer of a transparent, elastomeric polymer polydimethylsiloxane, PDMS against a Si 100 for the present work was a prepolymer of polydimethylsiloxane PDMS , an elastomer optically transparent down

  8. Graphane sheets and crystals under pressure Xiao-Dong Wena,2

    E-print Network

    Oganov, Artem R.

    that were more stable. Among these more stable structures were graphanes. We report here the three-dimensional, two on boat--are more stable thermodynamically than the isomeric benzene, or polyacetylene. Three-dimensional we found some saturated CH structures that were more stable than benzene, we began to look for more

  9. Understanding Source Package Organization using the Hybrid Model Xinyi Dong and Michael W. Godfrey

    E-print Network

    Godfrey, Michael W.

    criteria behind the package-level design of the system. This problem is exacerbated by the fact packages are organized is key to capturing the high-level design of an object-oriented system. Most the system's classes into this set of packages?" In this paper, we study package organization using

  10. Two Objects Not the Same = Liang ge dong xi bu yi yang.

    ERIC Educational Resources Information Center

    Matthews, John

    1997-01-01

    Studies how Singaporean children differentiate in drawing between a sphere and an elongated, straight-sided ovoid. Tests Piaget's and Inhelder's beliefs that very young children are unable to differentiate in their drawings between differently contoured shapes. Finds that children are able to show the difference in drawings between the two shapes.…

  11. SheJi HuoDong JiaoFa (The Project Approach). ERIC Digest.

    ERIC Educational Resources Information Center

    Katz, Lilian G.

    A project is an in-depth investigation of a topic worth learning more about, usually undertaken by a group of children within a class. The goal of a project is to learn more about a topic rather than to find answers to questions posed by a teacher. Project work is complementary to the systematic parts of a curriculum. Whereas systematic…

  12. Domain Transfer Multiple Kernel Learning Lixin Duan, Ivor W. Tsang, and Dong Xu, Member, IEEE

    E-print Network

    Tsang Wai Hung "Ivor"

    Abstract--Cross-domain learning methods have shown promising results by leveraging labeled patterns from, we propose a new cross-domain kernel learning framework into which many existing kernel methods can data sets) demonstrate that DTMKL-based methods outperform existing cross-domain learning and multiple

  13. Domain Transfer SVM for Video Concept Detection Lixin Duan Ivor W. Tsang Dong Xu

    E-print Network

    Xu, Dong

    @dcs.bbk.ac.uk Abstract Cross-domain learning methods have shown promising results by leveraging labeled patterns from concept detection, we propose a new cross-domain kernel learning method. Our method, referred to as Domain cor- pus demonstrate that DTSVM outperforms existing cross- domain learning and multiple kernel

  14. TCP Fast Recovery Strategies: Analysis and Improvements Dong Lin and H.T. Kung

    E-print Network

    Kung, H. T.

    -Reno and SACK), in reducing TCP retransmission timeouts (RTOs) and in being conservative in network usage during the fast recovery phase. Through a trace analysis, we have shown that over 85% of RTOs are due to small have shown that they significantly reduce RTOs and improve TCP's goodput. 1. Introduction With its

  15. Gesture Recognition Using Quadratic Curves Qiulei Dong, Yihong Wu, and Zhanyi Hu

    E-print Network

    Dong, Qiulei

    curvilinear integral and matrix computation are involved. Experi- ments on hip-hop dance show that our method can achieve a recognition rate as high as 97.65% on a database of 16 different gestures, each per

  16. Musician Map: visualizing music collaborations over time Ji-Dong Yim Chris Shaw Lyn Bartram

    E-print Network

    Shaw, Chris

    in a band. This allows the user to pursue social trend queries such as "Do Hip-Hop artists collaborate: "What was the most productive period of the Rolling Stones?", or "Do Hip-Hop artists collaborate data is drawn from the popular online databases MusicBrainz.org [24] and AudioScrobbler.net [3]. Music

  17. POD: A Parallel-On-Die Architecture Dong Hyuk Woo1

    E-print Network

    Lee, Hsien-Hsin "Sean"

    and manage system peripherals, the host processor is also responsible for controlling the featured massively instructions or stored directly back to the main memory. · SIMD PE Array Each PE tile consists of a high processors, and media accelerators. RRQ RRQ RRQ RRQ RRQ RRQ RRQ RRQ xTLBARB Host Processor LLC MC MC SystemMemory

  18. Quais as características propostas pelo BIRADS-US que melhor diferenciam nódulos malignos dos benignos? What characteristics proposed by BIRADS ultrasound better distinguish between benign and malignant nodes?

    Microsoft Academic Search

    EDUARDO CARVALHO PESSOA; CARLA PRISCILA KAMIYA; JOSÉ MORCELI; JOSÉ JOAQUIM GOMES NABUCO; HELOISA MARIA DE LUCA; GILBERTO UEMURA

    PURPOSE: to analyze which characteristics proposed by the BIRADS lexicon for ultrasound have the greatest impact on distinguishing between benign and malignant lesions. METHODS: ultrasonography features from the third edition of the BIRADS were studied in 384 nodes submitted to percutaneous biopsy from February 2003 to December 2006, at the Medical School of Botucatu. For the ultrasonography, the equipment Logic

  19. Graduat en Biologie mdicale, options chimie clinique et cytologie. Haute Ecole Andr Vsale Quai du Barbou, 2 4020 Lige -: 04/344 7812/14

    E-print Network

    Liège, Université de

    du Barbou, 2 à 4020 Liège - : 04/344 7812/14 Extraction de l'ADN de cellules végétales Matériel · Un blanc muqueux d'ADN genre « méduse ». · Prendre une pipette Pasteur dont on a replié l'extrémité effilée filament d'ADN. Retirer l'ADN et le déposer sur une lame pour microscope. · Si on dispose du colorant

  20. Analysis of the Correlation between Commodity Grade and Quality of Angelica sinensis by Determination of Active Compounds Using Ultraperformance Liquid Chromatography Coupled with Chemometrics.

    PubMed

    Wang, Zenghui; Wang, Dongmei; Huang, Linfang

    2014-01-01

    The contents of ferulic acid, senkyunolide A, butylidenephthalide, ligustilide, and n-butylphthalide were determined by UPLC analytical method; the correlation among the grade, average weight, and content was explored by correlation analysis and analysis of variance (ANOVA); the different commercial grades with average weight and content were revealed by principal component analysis (PCA) and then rationality analysis grade classification of A. sinensis. The results showed that various commercial grades can be distinguished by PCA analysis. And there was significant negative correlation between the commodity grades and average weight, commodity, and the content of bioactive compounds, while the content of senkyunolide A had significant negative correlation with commodity grades (P < 0.01). Average weight had no correlation with chemicals compounds. Additionally, there was significant positive correlation among the bioactive compounds (content of ferulic acid and phthalides) of different grades of A. sinensis. The content of senkyunolide A, butylidenephthalide, and ligustilide had significant positive correlation with the content of ferulic acid. The content of ligustilide and butylidenephthalide had significant positive correlation with the content of senkyunolide A. The content of ligustilide had significant positive correlation with the content of butylidenephthalide. The basis of grades classification is related with the difference levels of the bioactive compounds. PMID:24826193

  1. Experiments of trajectory generation and obstacle avoidance for a UGV David Vissi`ere, Dong Eui Chang, and Nicolas Petit

    E-print Network

    . In particular, autonomous vehicles are asked to bring fire power, communications, intelligence. Among oth- ers for guidance of autonomous vehicle. In facts, it is desired to alleviate the human operators burden. The more autonomous the vehicles are, the better. Two problems are identified: satisfy the mission goals and deal

  2. An Object-Oriented Design of a Multimedia Item Pool Wang Yue Dong Tiansi Xu Liangxian Lu ruzhan

    E-print Network

    Bremen, Universität

    of multimedia data, systems intended to store, transport, display and in general manage such data must have object-oriented? Conventional relational database system cannot manipulate complex objects effectively complex object system. While introducing object-oriented conception, the systems are empowered

  3. Temperature and Quantum Phase transition emerge due to entanglement H. Dong, S. Yang, X.F. Liu, , CPS , 2007

    E-print Network

    Sun, Chang-Pu

    of Thermodynamics #12;"PK" James Clerk Maxwell, Theory of Heat , 1871 Maxwell's demon #12;: Leo Szilard, 1932's Heat Engine Classical Quantum #12;Quantum thermodynamic cycle Assisted by Maxwell's Demon Quan et al = + + + Function of Maxwell's demon CNOT: obtain information 1,1 1,0 0,1 0,0 , , , ,(3) |1,0 1,0| |1',1 1',1| |0

  4. Decision Support System (DSS) for Sustainable Watershed Management in Dong Nai Watershed, Vietnam: Conceptual Framework and Proposed Research Techniques

    Microsoft Academic Search

    Ngyyen Kim Loi

    Decision makers today need to be able to ra pidly find good solutions to increasingly complex problems. Optimization based on decision support system (DSS) can help decision makers to meet this challenge. Building such systems, however, is expen sive and time consuming.The use of decision support system (DSS), linear programming (LP), and geographic information system (GIS) for sustainable watersh ed

  5. Brent Fultz, Tim Kelley, Mike McKerns, Jiao Lin, JaeDong Lee, Olivier Delaire, Max Kresch,

    E-print Network

    of thermal neutron scattering by S. W. Lovesey and G. L. Squires are superb. Similarly, excellent solid-state physics texts by J. M. Ziman, C. Kittel, U. R¨ossler, and N. W. Ashcroft and N. D. Mermin are available

  6. Blind Detection of Spread Spectrum Flow Weijia Jia, Fung Po Tso, Zhen Ling, Xinwen Fu, Dong Xuan and Wei Yu

    E-print Network

    Xuan, Dong

    -State University, Columbus, OH 43210 Cisco Systems, Inc., TX 75082 Abstract-- Recently, the direct sequence spread-spectrum], Yu et al. proposed a direct sequence spread spectrum (DSSS) based technique, which could be used

  7. Conduction in Charged PbSe Nanocrystal Films Brian L. Wehrenberg, Dong Yu, Jiasen Ma, and Philippe Guyot-Sionnest*

    E-print Network

    Yu, Dong

    corresponding to the complete filling of the 1Se state. The temperature and electric field dependence. Finally, the low-temperature behavior of the conductance and its field and temperature dependence be tuned with size, from 0.5 to 1 eV.2,3 IR electroluminescence,4 amplified stimulated emission,5 and high

  8. Fair Model Checking with Process Counter Abstraction Jun Sun, Yang Liu, Abhik Roychoudhury, Shanshan Liu and Jin Song Dong

    E-print Network

    Roychoudhury, Abhik

    of finding a bug which is exhibited by a fixed (and small) number of processes. This practice can abstraction for checking parameterized systems involves not keeping track of process identifiers by grouping algorithm enforces fairness by keeping track of the local states from where actions are enabled / executed

  9. A VLSI Implementation of Mixed-Signal mode Bipolar Neuron Circuitry Dong Pan, and Bogdan. M. Wilamowski

    E-print Network

    Wilamowski, Bogdan Maciej

    were paid to integrate the entire neural network circuit to CMOS VLSI chip, which will effectively --Neuron circuits have parallel operation features. VLSI implemented Neuron networks are suitable for high analog neuron circuits have smaller size. This paper presents a mixed-signal neuron design. It uses

  10. Seven different glucose-6-phosphate dehydrogenase variants including a new variant distributed in Lam Dong Province in southern Vietnam.

    PubMed

    Matsuoka, Hiroyuki; Thuan, Dang Thi Vinh; van Thien, Huynh; Kanbe, Toshio; Jalloh, Amadu; Hirai, Makoto; Arai, Meiji; Dung, Nguyen The; Kawamoto, Fumihiko

    2007-08-01

    We conducted a survey for glucose-6-phosphate dehydrogenase (G6PD) deficiency using blood samples from male outpatients of a local hospital in southern Vietnam. Most of the samples were from the Kinh (88.9%), the largest ethnic group in Vietnam, with a small number (11.1%) coming from the K'Ho, Chauma, Nung, and Tay minorities. We detected 25 G6PD-deficient cases among 1,104 samples (2.3%), and read the open reading frame of G6PD. A novel mutation (352T>C) predicting an aminoacid change of 118Tyr>His was found in a 1-year-old Kinh boy. His G6PD activity was estimated to be less than 10% residual activity, although he did not show chronic hemolytic anemia. Thus, we categorized this variant as Class II and named it G6PD Bao Loc. In the Kinh population, G6PD Viangchan (871G>A, 1311C>T, intron 11 nt93T>C), one of the most common variants in continental Southeast Asian populations, was the highest (6/19), followed by variants originating from the Chinese such as G6PD Canton (1376G>T) (5/19), G6PD Kaiping (1388G>A) (3/19), G6PD Gaohe (95A>G) (1/19), and G6PD Quing Yuan (392G>T) (1/19). In addition, G6PD Union (1360C>T) (2/19), which originated from the Oceania, was also detected. These findings suggest that the Kinh people are derived from various ancestries from continental Southeast Asia, China, and Oceania. In contrast, all of the 5 deficient cases in the K'Ho population were G6PD Viangchan, suggesting that they were very close to Southeast Asian populations such as the Khmer in Cambodia and the Lao in Laos. It is interesting that G6PD Mahidol (487G>A), another common variant in continental Southeast Asian populations in Myanmar, Thailand, and Malaysia, has not been detected from the Vietnamese. PMID:17726510

  11. A piperidine alkaloid and limonoids from Arisaema decipiens, a traditional antitumor herb used by the Dong people.

    PubMed

    Zhao, Fu-Wei; Luo, Min; Wang, Yue-Hu; Li, Ma-Lin; Tang, Gui-Hua; Long, Chun-Lin

    2010-11-01

    A new piperidine alkaloid and three known tetranortriterpenoids were isolated from the methanol extracts of the rhizomes of Arisaema decipiens Schott (Araceae) and their chemical structures were identified as (-)-(2R*,3S*,6S*)-N,2-dimethyl-3-hydroxy-6-(9-phenylnonyl) piperidine (1), 6-deacetylnimbin (2), 28-deoxonimbolide (3) and nimbin (4). The N-methylated derivative (1a) of 1 was synthesized. Compound 1 exhibited weak inhibitory activity against the MCF-7 cell line, while compound 1a showed potential inhibitory activity against the MCF-7 cell line with an IC?? value of 4.6 ?M and weak inhibitory activity against K562 and SK-OV-3 cells. This plant in genus Arisaema is firstly reported as the source of limonoids that are considered a natural antitumor herbal medicine. PMID:21116775

  12. Governing "Suzhi" and Curriculum Reform in Rural Ethnic China: Viewpoints from the Miao and Dong Communities in Qiandongnan

    ERIC Educational Resources Information Center

    Wu, Jinting

    2012-01-01

    This article examines the uptake of "suzhi"--roughly glossed as "quality"--in China's recent curriculum reform called "suzhi jiaoyu" (Education for Quality) in the rural ethnic context of Qiandongnan. It engages with three layers of analysis. First is a brief etymological overview of "suzhi" to map out its cultural politics in contemporary China.…

  13. Linger Longer: Fine-Grain Cycle Stealing for Networks of Workstations Kyung Dong Ryu Jeffrey K. Hollingsworth

    E-print Network

    Ryu, Kyung Dong

    that the Linger-Longer policy can improve the throughput of foreign jobs on cluster by 60% with only a 0.5% slow we present a new scheduling policy called Linger-Longer that exploits the fine-grained availability and use it to simulate a cluster of work- stations running our new policy. We compare two varia- tions

  14. The Dissertation Committee for Liang Dong certifies that this is the approved version of the following dissertation

    E-print Network

    Dong, Liang

    to Professor Xu, who, with great intelligence and incredible work ethic, provided me with both intellectual fields, and for his sharp scientific intuition, meticulous scholarship and warmheartedness, which have Xu Mobile broadband communication is experiencing rapid growth in technology, mar- kets and range

  15. HLA polymorphism of the Zhuang population reflects the common HLA characteristics among Zhuang-Dong language-speaking populations

    Microsoft Academic Search

    Li Shi; Xiao-qin Huang; Lei Shi; Yu-fen Tao; Yu-feng Yao; Liang Yu; Ke-qin Lin; Wen Yi; Hao Sun; Katsushi Tokunaga; Jia-you Chu

    2011-01-01

    A study of the human leukocyte antigen (HLA) genetic characteristics in the Zhuang, the largest ethnic population in China,\\u000a would provide insight into Zhuang history and give a useful tool for disease associations, transplantation, and anthropology.\\u000a In the present study, we report the comprehensive HLA-A, HLA-B, HLA-C, and HLA-DRB1 alleles and haplotypes in the Zhuang population\\u000a of southern China for

  16. LHash: A Lightweight Hash Function (Full Version) Wenling Wu, Shuang Wu, Lei Zhang, Jian Zou, and Le Dong

    E-print Network

    in Hirosei's double-block mode [17]. The ARMADILLO [2] hash function proposed at CHES 2010 was found to be insecure. Then a new version of ARMADILLO (version 3) [33] was proposed at CARDIS 2012. QUARK [1] uses

  17. Upriver to Hue and Dong Ha: The U.S. Navy's War in I Corps, Vietnam 1967-1970 

    E-print Network

    Chavanne, Jonathan Blackshear

    2012-02-14

    and National Liberation Front cadres. A demanding taskmaster, Felt had grown weary of the optimistic reports then being generated and gave Bucklew simple instructions: get me the facts and get them fast. Felt wanted an honest assessment of not only...

  18. Influence of Tip-induced Band Bending on Tunneling Spectra of Semiconductor R. M. Feenstra and Y. Dong

    E-print Network

    Feenstra, Randall

    and compared with data obtained from p-type GaAs surfaces, and generalization of the method to semiconductorInfluence of Tip-induced Band Bending on Tunneling Spectra of Semiconductor Surfaces R. M. Feenstra a metal tip and a semiconductor surface. Tip-induced band bending in the semiconductor is included

  19. Circulation and multiple-scale variability in the Southern California Bight Changming Dong a,*, Eileen Y. Idica b

    E-print Network

    Dong, Changming "Charles"

    against extensive observational data: High-Frequency (HF) radar data, current meters, Acoustic Doppler currents are much stronger than the wind-driven Ekman flows at the surface. The model exhibits intrinsic by the large-scale California Current offshore, tropical remote forcing through the coastal wave guide

  20. Well-defined star-shaped calcite crystals formed in agarose gels Dong Yang, Limin Qi* and Jiming Ma

    E-print Network

    Qi, Limin

    CO3 in hydrogels formed by polysaccharides.11 It is noteworthy that the silk fibroin in mollusk shell hydrogels,9 have received considerable attention. It is noted that insoluble polysaccharide matrices organic matrices exists in the form of a hydrogel, indicating that gel matrices play an important part

  1. A Fast Batched Cholesky Factorization on a GPU Tingxing Dong, Azzam Haidar, Stanimire Tomov, and Jack Dongarra

    E-print Network

    Dongarra, Jack

    in HPC. An indicator for it is given by the performance-per-watt measure. As Eq. 3 demonstrates) or matrix-vector(dgemv) products of matrices of well over 100x100 [6]. NVIDIA also includes batched dgemm, Gauss, and Householder factorizations are based on block outer-product updates of the trailing matrix

  2. Educational and Social Development in Doi Ang Khang: A Comparative Study of the Khob Dong and Nor Lae Villages

    ERIC Educational Resources Information Center

    Frost, Timothy; Gray, Lauren; Lake, John; Roy, Jessica

    2007-01-01

    Northern Thailand is home to many hill tribes, who have lived for hundreds of years as subsistence farmers or nomadic hunters. In the 1940s, communist insurgencies drove many hill tribes from China, Burma, and other nations south into northern Thailand. Uprooted from their native lands, the hill tribes left behind ties to economic resources and,…

  3. Korean Confucianism's Mindful Learning Model of Moral Internalization as Manifested in the Cheonghak-Dong Hermit Community

    ERIC Educational Resources Information Center

    Yoo, Si Ha

    2012-01-01

    The purpose of this qualitative study is to understand an unknown educational approach in Korean Confucianism's ethical education characterized as moral internalization, based on the study participants. A prevailed understanding of moral internalization of Confucianism is a strong imposed learning process, which is a well known Asian learning…

  4. The Implementation of Standards-Based Teacher Evaluation in Vietnamese Secondary Schools: A Case Study in Dong Thap

    ERIC Educational Resources Information Center

    Pham, Huy Q.

    2013-01-01

    Teacher quality has become a critical area of concern in Vietnamese education. Recently, new professional standards for teachers in secondary schools have been developed, piloted, and implemented. This study explores the perceptions of teachers, school principals, and other administrators about the new teacher professional standards, the…

  5. Dong-Ah Lee+, Eui-sub Kim+, Junbeom Yoo+, Jang-Soo Lee*, Jong Gyun Choi* +Konkuk University

    E-print Network

    , Ewha Womans University, Seoul, Korea #12;Outline 1. Introduction 2. Background 1. NuDE 2. Function into NuDE which is based on eclipse plug-in environment. · Input: PLCopen TC6 XML version 2.01 scheme (de

  6. Youngju Seo*, Dong-Ah Lee, and Junbeom Yoo An Automatic Assistant for Fault Tree Analysis of

    E-print Network

    to save programs written in languages of IEC 61131-3 9 Function block diagram #12;Background ­ NuDE Nuclear development environment (NuDE) Development environment for safety-critcial software of nuclear

  7. Denial-of-Service Attacks on Battery-powered Mobile Computers Thomas Martin, Michael Hsiao, Dong Ha, Jayan Krishnaswami

    E-print Network

    Ha, Dong S.

    , which Stajano and Anderson have called a sleep deprivation torture attack, or battery exhaustion [18 to the creation and spread of sleep deprivation torture attacks. The battery in a pervasive computing device

  8. Motion Planning for a Mobile Manipulator with Imprecise Locomotion Dong Hun Shin, Bradley S. Hamner, Sanjiv Singh, and Myung Hwangbo

    E-print Network

    Singh, Sanjiv

    @uos.ac.kr The Robotics Institute Carnegie Mellon University {bhamner,myung}@andrew.cmu.edu, ssingh@ri.cmu.edu ABSTRACT with implementation on a mobile manipulator are discussed. I. INTRODUCTION Mobile robots have long been used in applications such as material transport and exploration where the task of the robot is stated as getting from

  9. Michael B. Ek1, Youlong Xia1,2, Jesse Meng1,2, and Jiarui Dong1,2

    E-print Network

    Yang, Zong-Liang

    Environmental Modeling Center (EMC) National Centers for Environmental Prediction (NCEP) National Weather/EMC NOAA Center for Weather and Climate Prediction College Park, Maryland Texas Drought Forum, Austin Monitor (USDM) editing process via GIS. 9 #12;NLDAS GIS data are an integral part of the USDM process

  10. Development of a Universal Networked Timer P. Sichta, J. Dong, J.E. Lawson, G. Oliaro, J. Wertenbaker

    E-print Network

    Princeton Plasma Physics Laboratory

    component based upon an FPGA. The first generation device was called the Multifunction Timing System (MTS features Field Programmable Gate Array (FPGA) technology which allows each of its eight channels in a rack-mount PC along with other data acquisition boards, forming a PC-based control and data acquisition

  11. Antithrombotic effects of naturally derived products on coagulation and platelet function.

    PubMed

    Mousa, Shaker A

    2010-01-01

    To date, there have been few systematic studies of the antiplatelet and/or anticoagulant effects of natural products. According to the Natural Medicines Comprehensive Database, approximately 180 dietary supplements have the potential to interact with warfarin, and more than 120 may interact with aspirin, clopidogrel, and dipyridamole. These include anise and dong quai (anticoagulant effects); omega 3-fatty acids in fish oil, ajoene in garlic, ginger, ginko, and vitamin E (antiplatelet properties); fucus (heparin-like activity); danshen (antithrombin III-like activity and anticoagulant bioavailability); and St. John's Wort and American Ginseng (interference with drug metabolism). Other supplements, such as high doses of vitamin E (vitamin K antagonist activity), alfalfa (high-vitamin K content), and coenzyme Q10 (vitamin K-like activity), may affect blood clotting, which is dependent on vitamin K. Studies are needed to understand the role of various dietary supplements in thrombosis and their interactions with standard anticoagulants and antiplatelet drugs. PMID:20617421

  12. L'esperimento CMS http://www.roma1.infn.it/exp/cms/

    E-print Network

    Roma "La Sapienza", Università di

    Barone, Alessandro Bartoloni, Giulio Capradossi, Francesca Cavallari, Angelica Cecilia, Ioan Dafinei, Danilo D'Angelo, Francesco de Notaristefani, Daniele del Re, Marcella Diemoz, Giuseppe Ferrara, Corrado

  13. The phylogenetic position of Peucedanum sensu lato and allied genera and their placement in tribe Selineae (Apiaceae, subfamily Apioideae)

    Microsoft Academic Search

    K. Spalik; J.-P. Reduron; S. R. Downie

    2004-01-01

    ITS sequences of members of Peucedanum and its segregates ( Cervaria, Holandrea, Imperatoria, Oreoselinum, Pteroselinum, Thysselinum, Tommasinia, and Xanthoselinum), as well as representatives of other members of the previously identified ‘ Angelica’ and ‘ Arracacia’ clades, were analysed using distance, maximum likelihood, and maximum parsimony methods in order to establish their phylogenetic relationships. The ‘ Angelica’ and ‘ Arracacia’ clades

  14. The phylogenetic position of Peucedanum sensu lato and allied genera and their placement in tribe Selineae (Apiaceae, subfamily

    E-print Network

    Downie, Stephen R.

    segregates are closely related to one another and to Peucedanum sensu stricto. The genera Seseli and Selinum are polyphyletic. Members of the genus Angelica form a single clade that also includes representatives of Selinum) are proposed, and Selinum pyrenaeum is recognised in Angelica (A. pyrenaea). Key words: Peucedanum, Apiaceae

  15. Influence of Cell Volume in Multicell Transplant Flats on the Growth of Organically Grown Seedlings of Medicinal Plants

    Microsoft Academic Search

    E. Herrera; N. Tremblay; A. Gosselin

    1996-01-01

    Multi-cell transplant flats were compared to determine the influence of cell volume on the growth and nutritional condition of seedlings of angelica (Angelica archangelica L.), horehound (Marrubium vulgare L.) and thyme (Thymus vulgaris L.) grown in organic media. Plant growth and mineral concentration generally increased with cell volume, though the effect varied with different plant species. An increase in cell

  16. Optimization of Substrate and Nutrient Solution for Organic Cultivation of Medicinal Transplants in Multicell Flats

    Microsoft Academic Search

    Elizabeth Herrera; Nicolas Tremblay; Bruno Desroches; Andre Gosselin

    1997-01-01

    Seedlings of angelica (Angelica archangelica L.), horehound (Marrubium vulgare L.) and thyme (Thymus vulgaris L.) were grown in multicell flats, filled with peat-compost mixtures containing different levels of compost. The plants, fertilized with nutrient solutions made of compost extracts diluted to selected electrical conductivities, increased in shoot and root dry weight and Contained higher mineral concentration when the percentage of

  17. RECONFIGURABLE MODEM ARCHITECTURE FOR CDMA BASED 3G HANDSETS Ramesh Chembil Palat, *Jina Kim, *Jong Suk Lee, *Dr. Dong S. Ha, **Dr. Cameron Patterson, Dr.

    E-print Network

    Ha, Dong S.

    RECONFIGURABLE MODEM ARCHITECTURE FOR CDMA BASED 3G HANDSETS Ramesh Chembil Palat, *Jina Kim, *Jong remain a challenge. In this paper we present a design methodology to develop reconfigurable modem (RM radio handsets. In this paper we present the design methodology for a CCM based reconfigurable modem

  18. The versatile conversion of acyclic amides to a-alkylated amines Young-Ger Suh,* Dong-Yun Shin, Jae-Kyung Jung and Seok-Ho Kim

    E-print Network

    Suh, Young-Ger

    N-acyliminium ions. The use of a-alkoxy carbamates and amides as precursors for N-acyliminium ions addition of amides or carbamates to aldehydes,3 or oxidation of the hydrocarbon under electrochemical and tert-butyl carbamates were superior to the methyl carbamate in terms of yield. Other trapping reagents

  19. Multimodal Emotion Recognition using EEG and Eye Tracking Data Wei-Long Zheng, Bo-Nan Dong and Bao-Liang Lu* Senior Member, IEEE

    E-print Network

    Lu, Bao-Liang

    emotion-relevant features from EEG signals and eye tracing data of 12 experiments and build a fusion model that both feature level fusion and decision level fusion combining EEG signals and eye tracking data can, various signals have been adopted, which can be roughly classified into two categories: non-physiological

  20. Exemplar-based Visualization of Large Document Corpus Yanhua Chen, Student Member, IEEE, Lijun Wang, Ming Dong, Member, IEEE, and Jing Hua, Member, IEEE

    E-print Network

    Hua, Jing

    to a low dimensional space using parameter embedding. By selecting the representative exemplars, we obtain. Index Terms--Exemplar, large-scale document visualization, multidimensional projection. 1 INTRODUCTION and an adverse event of interest. Thus, text mining, a technique of deriving high-quality knowledge from text

  1. Chemical Data Mining of the NCI Human Tumor Cell Line Database Huijun Wang, Jonathan Klinginsmith, Xiao Dong, Adam C. Lee, Rajarshi Guha, Yuqing Wu,

    E-print Network

    Wu, Yuqing Melanie

    Chemical Data Mining of the NCI Human Tumor Cell Line Database Huijun Wang, Jonathan Klinginsmith Tenth Street, Bloomington, Indiana 47408, and College of Pharmacy, University of Michigan, 428 Church Human Tumor cell line data set is a publicly available database that contains cellular assay screening

  2. High prevalence of vitamin D deficiency in adults aged 50 years and older in Gwangju, Korea: the Dong-gu Study.

    PubMed

    Song, Hye-Rim; Kweon, Sun-Seog; Choi, Jin-Su; Rhee, Jung-Ae; Lee, Young-Hoon; Nam, Hae-Sung; Jeong, Seul-Ki; Park, Kyeong-Soo; Ryu, So-Yeon; Choi, Seong-Woo; Shin, Min-Ho

    2014-01-01

    Vitamin D plays an important role in bone metabolism and maintaining bone health. Recently, new evidence has revealed that vitamin D affects chronic diseases such as autoimmune diseases, cardiovascular diseases and certain cancers. The aim of this study was to evaluate the vitamin D status and the prevalence of vitamin D deficiency in an urban Korean population. This study included 8,976 participants (3,587 men and 5,389 women) aged 50 yr and older. Serum 25(OH)D level was measured by chemiluminescent microparticle immunoassay. The prevalence of vitamin D deficiency [25(OH)D < 20 ng/mL] was 59.7% and 86.5% in men and women, respectively. The prevalence of vitamin D deficiency increased significantly with age in men, but not in women and it decreased from April to July, more prominently in men than in women. These results suggest that sun exposure, intake of vitamin D supplement, and regular physical activities is recommended in an urban Koreans, especially in women. PMID:24431921

  3. The prevalence and correlation of carotid artery calcification on panoramic radiographs and peripheral arterial disease in a population from the Republic of Korea: the Dong-gu study

    PubMed Central

    Lee, J-S; Kim, O-S; Chung, H-J; Kim, Y-J; Kweon, S-S; Lee, Y-H; Shin, M-H; Yoon, S-J

    2013-01-01

    Objectives: The aim of this study was to determine the prevalence of carotid artery calcification (CAC) detected on panoramic radiographs and peripheral arterial disease (PAD), and to evaluate the difference in the prevalence of PAD between patients with CAC and patients without CAC detectable by panoramic radiograph. Methods: The surveyed population consisted of 4078 subjects aged 50 years and older (1410 males and 2668 females) who underwent medical and dental examination in Gwangju city, South Korea. Two oral and maxillofacial radiologists interpreted the panoramic radiographs for the presence of carotid artery calcification. A trained research technician measured the ankle–brachial index (ABI). An ABI <0.9 in either leg was considered evidence of PAD. Results: The prevalence of CAC on panoramic radiographs was 6.2% and that of PAD was 2.6%. Subjects with CAC had a significantly higher prevalence of PAD than those without CAC (5.5% vs 2.4%, respectively). The presence of CAC on panoramic radiographs was associated with PAD (odds ratio 1.84; 95% confidence interval 1.01–3.36) after adjusting for potential confounders. Conclusion: CACs detected on panoramic radiographs were positively associated with PAD in middle-aged and older Korean adults. PMID:22752323

  4. Pharmacokinetic and pharmacodynamic profiles of the antitussive principles of Glycyrrhizae radix (licorice), a main component of the Kampo preparation Bakumondo-to (Mai-men-dong-tang).

    PubMed

    Kamei, Junzo; Saitoh, Akiyoshi; Asano, Takayuki; Nakamura, Rie; Ichiki, Hiroyuki; Iiduka, Akira; Kubo, Masayoshi

    2005-01-10

    We examined the pharmacokinetic and pharmacodynamic properties of liquiritin apioside, a main antitussive component of Glycyrrhizae radix (licorice), with regard to its antitussive effect in guinea pigs. The peak plasma concentration of the unchanged compound was observed 15 min after the administration of liquiritin apiosaide. The plasma concentration then gradually decreased and was almost undetectable 4 h after administration. Liquiritigenin, a des-glycoside of liquiritin apioside, appeared in the plasma 2 h after the administration of liquiritin apioside and remained for more than 6 h after administration. The plasma concentration of unchanged liquiritigenin was observed 15 min after administration and then gradually increased for more than 6 h after administration. When the antitussive effects of liquiritin apioside, liquiritin and liquiritigenin, at respective doses of 30 mg/kg, p.o., were examined 1 h after administration, liquiritin apioside and liquiritigenin caused a significant reduction in the number of capsaicin-induced coughs. However, at the same dose, liquiritin had no significant effect on the number of capsaicin-induced coughs. On the other hand, when the antitussive effects of liquiritin apioside, liquiritin and liquiritigenin, at doses of 30 mg/kg, p.o., were examined 4 h after administration, each caused a more than 40% reduction in the number of capsaicin-induced coughs. The present results suggest that G. radix (licorice) may produce a persistent antitussive effect, and that liquiritin apioside plays an important role in the earlier phase, while liquiritigenin, which is a metabolite of liquiritin apioside and liquiritin, plays an important role in the late phase. PMID:15659306

  5. High Prevalence of Vitamin D Deficiency in Adults Aged 50 Years and Older in Gwangju, Korea: the Dong-gu Study

    PubMed Central

    Song, Hye-Rim; Kweon, Sun-Seog; Choi, Jin-Su; Rhee, Jung-Ae; Lee, Young-Hoon; Nam, Hae-Sung; Jeong, Seul-Ki; Park, Kyeong-Soo; Ryu, So-Yeon; Choi, Seong-Woo

    2014-01-01

    Vitamin D plays an important role in bone metabolism and maintaining bone health. Recently, new evidence has revealed that vitamin D affects chronic diseases such as autoimmune diseases, cardiovascular diseases and certain cancers. The aim of this study was to evaluate the vitamin D status and the prevalence of vitamin D deficiency in an urban Korean population. This study included 8,976 participants (3,587 men and 5,389 women) aged 50 yr and older. Serum 25(OH)D level was measured by chemiluminescent microparticle immunoassay. The prevalence of vitamin D deficiency [25(OH)D < 20 ng/mL] was 59.7% and 86.5% in men and women, respectively. The prevalence of vitamin D deficiency increased significantly with age in men, but not in women and it decreased from April to July, more prominently in men than in women. These results suggest that sun exposure, intake of vitamin D supplement, and regular physical activities is recommended in an urban Koreans, especially in women. PMID:24431921

  6. Department of Sport Science, Seoul National University of Science and Technology, 172 Gongneung-dong, Nowon-gu, 139-743 Seoul, South Korea.

    PubMed

    Kim, Youngho

    2013-06-01

    The current study investigated differences in physical activity and perceived benefits and barriers in normal-weight, overweight, and obese adolescents and tested the effect of BMI and perceived benefits and barriers on physical activity. Adolescents (N = 773) participated in the study; 381 were classified as having normal weight, 262 as overweight, and 130 as obese. Leisure Time Physical Activity Questionnaire, Decisional Balance Scale, and body composition analyzer were used to measure the study variables. Results indicated that there were no differences in self-reported physical activity in the three BMI groups. However, groups perceived benefits of and barriers to physical activity differed. BMI and 'better outlook', 'weight control', 'feeling confidence', 'physical dissatisfaction', and 'lack of confidence' accounted for nearly half the variance in self-reported physical activity. PMID:24175467

  7. Accommodate street vendors during the urban development process : with two empirical cases of Zhu Lian (ZL), and Guan Dong (GD) public markets in Hsinchu City, Taiwan

    E-print Network

    Weng, Chia Yang

    2013-01-01

    Every day, the recurring scene of conflict between street vendors and municipal authorities can be found in virtually every major city around the world. Through licensing, zoning, or relocating, municipal governments devise ...

  8. Mud deposition on the meso-tidal beach due to Typhoon Durian on 4-5th December 2006 in BaDong beach, Vietnam

    NASA Astrophysics Data System (ADS)

    Nanayama, F.; Horaguchi, K.; Ta, O. T.; Watanabe, K.; Tateishi, R.; Yamaguchi, T.; Tamura, T.; Nguyen, L. V.; Murakami, F.; Saito, Y.; Tateishi, M.

    2008-12-01

    BaDnog beach is located in the southeastern margin of the Mekong River Delta, Tra Vinh province, southern Vietnam"CIt is a typical meso-tidal beach system. Since November 2005 we have repeatedly studied surface sedimentation and morphological change controlled by Asian monsoon effects. On March 2007, we described strange mud layers and mud clasts around the high-tide shoreline on Lines A and BT. The diameters of the mud clasts are 1-30 cm and the roundness varies from angular block shape to ellipse spherical shape. Furthermore, we dug among sand bars near the coast and high-tide shoreline. Then we found some mud layers under the beach and sand bars. According to comparison with field data of March 2007 and November 2006, we summarized five important characteristics: (1) Mud layers were found only in the south area such as Lines A and BT because this area had a depositional tendency during March 2007 and November 2006. (2) Mud layers were distributed between the surfaces of March 2007 and November 2006, and mostly spread over the surface of November 2006. (3) The thickness of the mud layers is 1-30 cm. The maximum number of mud layers is three. These are associated with thin sand layers, which consist of very fine sand, derived from beach and associated traction structures such as plane bed and wave ripple. (4) The mud includes much organic materials and its color suggests a subtidal mud origin. The southern Vietnam region has rarely been damaged by strong typhoon since 1997. But, Typhoon Durian hit Vietnam's southern regions on 4-5th December, 2006. We guess the mud layers were brought from the subtidal area to the high-tide shoreline due to the strong waves of this typhoon. Also we guess the mud clasts were washed out from buried mud layers under the beach and sand bars due to the strong waves during the winter monsoon after the typhoon.

  9. CitySee: Urban CO2 Monitoring with Sensors Xufei Mao, Xin Miao, Yuan He, Tong Zhu, Jiliang Wang, Wei Dong, Xiang-Yang Li, and Yunhao Liu

    E-print Network

    Liu, Yunhao

    CitySee: Urban CO2 Monitoring with Sensors Xufei Mao, Xin Miao, Yuan He, Tong Zhu, Jiliang Wang CitySee, a real-time CO2-monitoring system using sensor networks for an urban area (around 100 square network consisting of 1096 relay nodes and 100 sensor nodes in Wuxi City, China. Index Terms--CO2

  10. 134 Shinchon-Dong,Sodaemun-ku, Seoul 120-749, Korea Tel. (82-2)2123-2114 Fax. (82-2) 392-0618

    E-print Network

    Burgstaller, Bernd

    International Programs 10 Undergraduate Admission Guide 12 Information for Students Undergraduate Studies 16 College of Theology 28 College of Social Science 29 College of Law 30 College of Music 31 College of Human of learning based on the principles of Christian teaching, one which strives to educate leaders who

  11. Taegtmeyer, Kenneth B. Margulies, Bruce D. Hammock and Florin Despa Sanda Despa, Savita Sharma, Todd R. Harris, Hua Dong, Ning Li, Nipavan Chiamvimonvat, Heinrich

    E-print Network

    Hammock, Bruce D.

    - induced cardiac oxidative stress and Ca2+ dysregulation. Conclusions---The results suggest blood amylin stress and Ca2+ dysregulation. In time, HIP rats developed cardiac hypertrophy and left- ventricular aggregates interact directly with cardiac myocytes and whether controlling hyperamylinemia protects the heart

  12. Reduction of native oxides on GaAs during atomic layer growth of Al2O3 Hang Dong Lee,a

    E-print Network

    Gustafsson, Torgny

    is studied using medium energy ion scattering spectroscopy MEIS and x-ray photoelectron spectroscopy XPS ALD growth with in situ character- ization by medium energy ion scattering spectroscopy MEIS . Films ultrahigh vacuum UHV to the MEIS analysis system base pressure 6 10-10 Torr . Medium energy ion scattering

  13. Co-Labeling: A New Multi-view Learning Approach for Ambiguous Problems Wen Li1 Lixin Duan2 Ivor Wai-Hung Tsang1 Dong Xu1

    E-print Network

    Tsang Wai Hung "Ivor"

    Co-Labeling: A New Multi-view Learning Approach for Ambiguous Problems Wen Li1 Lixin Duan2 Ivor Wai SAP Research, SAP AG, Singapore, 117440 wli1@e.ntu.edu.sg lxduan@gmail.com ivortsang@ntu.edu.sg dongxu@ntu.edu.sg Abstract--We propose a multi-view learning approach called co-labeling which is applicable for several

  14. (196), rs10. [DOI: 10.1126/scisignal.2002029]4Science Signaling Berger and Norbert Perrimon (25 October 2011)

    E-print Network

    Perrimon, Norbert

    , Dong Yan, Arunachalam Kinase and Ras to Extracellular Signal-Regulated Kinase Signaling Proteomic Singh,4 Dong Yan,1,2 Arunachalam Vinayagam,1,2 Yanhui Hu,1,2 Richard Binari,1,2 Pengyu Hong,5 Xiaoyun

  15. A well-mixed warm water column in the central Bohai Sea in summer: Effects of tidal and surface wave mixing

    E-print Network

    Xie, Shang-Ping

    with the Yellow Sea through the Bohai Strait between Shan Dong and Liao Dong Peninsulas (Figure 1). As the only. The cold bottom water originates from the Yellow Sea, flowing into the Bohai Sea along the north side

  16. A Framework for Handling Dependencies among Web Services Transactions

    E-print Network

    A Framework for Handling Dependencies among Web Services Transactions Seunglak Choi KAIST 371-1 Guseong-Dong, Yuseong-Gu, Daejeon, Korea slchoi@dbserver.kaist.ac.kr Jungsook Kim ETRI 161 Gajeong-dong, Yuseong-gu, Daejeon, Korea jungsook96@etri.re.kr Hyukjae Jang KAIST 371-1 Guseong-Dong, Yuseong

  17. Change in protective coloration in the striated shieldbug Graphosoma lineatum (Heteroptera: Pentatomidae)

    E-print Network

    Tullberg, Birgitta

    , the epidermis is pale, light brownish (Tullberg et al. 2008; Fig. 1), which match the background of dried umbels podagraria, Angelica sylvestris etc.) on which the bugs are found. This is supported by the reflectance

  18. Biosensors and Bioelectronics 22 (2007) 30283035 Microresonator mass sensors for detection of Bacillus

    E-print Network

    Bashir, Rashid

    2007-01-01

    of Bacillus anthracis Sterne spores in air and water Angelica P. Davilaa, Jaesung Janga, Amit K. Guptaa,1, Tom of microcantilevers as resonant mass sensors for detection of Bacillus anthracis Sterne spores in air and liquid

  19. On the use of cheap talk in hypothetical product valuation: a field experiment

    E-print Network

    Silva, Andres

    2009-05-15

    each Departmental procedure. As for my friends, Angelica, Paco, David, Alejandro, Lindsey, Ben and Dave taught me the value of tolerance and loyalty in the best possible way. I would like to thank my family for their unconditional support...

  20. Geology of the Carlos-East area, Grimes County, Texas

    E-print Network

    Walton, William Lawrence

    1959-01-01

    Augustine, ' and angelica counties. . H? mapped the remainder of those strata that are J t' included in the present-day Jackson group as catahoula formation. ' . 18 Figure 3 GENESIS OF JACKSON GROUP NOMENCLATURE Penross 1890 Dumble 1892 Kennedy...

  1. Some statistical associations between Northern Hemisphere sea level pressure patterns and temperatures at selected U.S. climate stations

    E-print Network

    Bryan, Janine Marie

    1988-01-01

    Hartington, NE Hay Springs, NE Imperial, NE Kimball, NE Loup City, NE Madison, NE Minden, NE North Loup, NE St. Paul, NE Wakefiteld, NE Bethlehem, NH Belvidere, NJ Charlottesburg, JN Flemington, JN Angelica, NY Hemlock, NY Lowville, NY Mohonk...

  2. 78 FR 75332 - Grain-Oriented Electrical Steel From the People's Republic of China: Postponement of Preliminary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ...Trade Administration, Department of Commerce. FOR FURTHER INFORMATION CONTACT: Yasmin Nair at (202) 482-3813 or Angelica Mendoza at (202) 482-3019, AD/CVD Operations, Office VI, Enforcement and Compliance, International Trade...

  3. 76 FR 18156 - Purified Carboxymethylcellulose From the Netherlands: Extension of Time Limit for Preliminary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ...Commerce. DATES: Effective Date: April 1, 2011. FOR FURTHER INFORMATION CONTACT: Dena Crossland, Brian Davis, or Angelica Mendoza, Office 7, AD/CVD Operations, Import Administration, International Trade Administration, U.S. Department of...

  4. Analysis of condensate banking dynamics in a gas condensate reservoir under different injection schemes

    E-print Network

    Sandoval Rodriguez, Angelica Patricia

    2002-01-01

    ANALYSIS OF CONDENSATE BANKING DYNAMICS IN A GAS CONDENSATE RESERVOIR UNDER DIFFERENT INJECTION SCHEMES A Thesis by ANGELICA PATRICIA SANDOVAL RODRIGUEZ Submitted to the Office of Graduate Studies of Texas A&M University in partial... fulfillment of the requirements for the degree of MASTER OF SCIENCE August 2002 Major Subject: Petroleum Engineering ANALYSIS OF CONDENSATE BANKING DYNAMICS IN A GAS CONDENSATE RESERVOIR UNDER DIFFERENT INJECTION SCHEMES A Thesis by ANGELICA PATRICIA...

  5. Electron fishbones: theory and experimental evidence F. Zonca 1), P. Buratti 1), A. Cardinali 1), L. Chen 2)-3), J.-Q. Dong 4), Y.-X. Long 4), A.

    E-print Network

    Zonca, Fulvio

    1 TH/3-2 Electron fishbones: theory and experimental evidence F. Zonca 1), P. Buratti 1), A of fishbone-like internal kink instabilities driven by supra-thermal electrons generated experimentally. The peculiarity and interest of exciting these electron fishbones by ECRH only or by LH only is also analyzed

  6. Lithium, Sodium, and Potassium Abundances in Sharp-Lined A-Type Stars Takeda, Yoichi; Kang, Dong-Il; Han, Inwoo; Lee, Byeong-Cheol; Kim, Kang-Min; Kawanomoto, Satoshi; Ohishi, Naoko;

    NASA Astrophysics Data System (ADS)

    2012-04-01

    The abundances of alkali elements (Li, Na, and K) were determined from the Li I 6708, Na I 5682/5688, and K I 7699 lines by taking into account the non-LTE effect for 24 sharp-lined A-type stars (ve sin i ? 50 km s-1, 7000 K &lesssim Teff &lessim 10000 K, many showing Am peculiarities to different degrees), based on high-dispersion and high-S/N spectral data secured at BOAO (Korea) and OAO (Japan). We found a significant trend that A(Na) tightly scales with A(Fe) irrespective of Teff, which means that Na becomes enriched similarly to Fe in accordance with the degree of Am peculiarity. Regarding lithium, A(Li) mostly ranges between ˜ 3 and ˜ 3.5 (i.e., almost the same as or slightly less than the solar system abundance of 3.3) with a weak decreasing tendency with a lowering of Teff at Teff &lesssim 8000 K, though several stars exceptionally show distinctly larger depletion. The abundances of potassium also revealed an apparent Teff-dependence in the sense that A(K) in late-A stars tends to be mildly subsolar [possibly with a weak anti-correlation with A(Fe)] systematically decreasing from ˜ 5.0 (Teff ˜ 8500 K) to ˜ 4.6 (Teff ˜ 7500 K), while those for early-A stars remain near-solar around ˜ 5.0-5.2. These observational facts may serve as important constraints for any theory aiming to explain chemical anomalies of A-type stars.

  7. COMPACT MODEL OF SLUG FLOW IN MICROCHANNELS Dong Rip Kim, Jae-Mo Koo, Chen Fang, Julie E. Steinbrenner, Eon Soo Lee, Fu-Min Wang, Carlos H. Hidrovo,

    E-print Network

    Hidrovo, Carlos H.

    and advancing/receding triple point contact angles as its only inputs. The results indicate that the pressure of pressure drop and liquid water coverage ratio, key parameters in the operation of Proton Exchange Membrane is capable of predicting liquid water coverage ratio and pressure drop using liquid and gas flow rates

  8. Volume Exploration using Ellipsoidal Gaussian Transfer Functions Yunhai Wang 1,2, Wei Chen 3, Guihua Shan 1,2, Tingxin Dong 1,2, and Xuebin Chi 2

    E-print Network

    Chen, Wei

    on ellipsoidal Gaussian transfer functions (ETFs). Our ap- proach explores volumetric features in the statistical these Gaussians to ETFs and analytically integrating these ETFs in the context of the pre-integrated volume

  9. Anisotropy of Charpy Properties in API-X80 Steels MinSung Jooa, Dong-Woo Suha, Jin-Ho Baeb and H. K. D. H. Bhadeshiaa,c

    E-print Network

    Cambridge, University of

    .25Si-~1.8Mn-~0.01P-~0.001S wt% with alloying elements Mo, Ni, Cu, Ti , Nb ,V. Good Weldability - Ceq~724 MPa Yield Ratio 93 % 81~87 % CVN Energy at -40°C 110 J 300~350 J API-X80 Steel Fe-(0.05~0.07)C-0 is weakest at room temperature. RD Mohan, R. et al., NUREG/CR-6299, BMI-2184, 1995 Energy absorbed by Charpy

  10. Copyright Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited. Profiling the regulatory lipids: another systemic way to unveil the

    E-print Network

    Hammock, Bruce D.

    Copyright © Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited. Profiling the regulatory lipids: another systemic way to unveil the biological mystery Jun Yang, Hua Dong

  11. Specialty Supplements and Breast Cancer Risk in the VITamins And Lifestyle (VITAL) Cohort

    PubMed Central

    Brasky, Theodore M.; Lampe, Johanna W.; Potter, John D.; Patterson, Ruth E.; White, Emily

    2010-01-01

    Background Use of non-vitamin, non-mineral “specialty” supplements has increased substantially over recent decades. Several supplements may have anti-inflammatory or anti-cancer properties. Additionally, supplements taken for symptoms of menopause have been associated with reduced risk of breast cancer in two case-control studies. However, there have been no prospective studies of the association between the long-term use of these supplements and breast cancer risk. Methods Participants were female members of the VITamins And Lifestyle (VITAL) Cohort. Postmenopausal women, age 50-76 years, who were residents of western Washington State completed a 24-page baseline questionnaire in 2000-2002 (n=35,016). Participants were queried on their recency (current vs. past), frequency (days/week), and duration (years) of specialty supplement use. Incident invasive breast cancers (n=880) from 2000-2007 were obtained from the Surveillance, Epidemiology and End Results registry. Multivariable-adjusted hazards ratios (HR) and 95% confidence intervals (95% CI) were estimated by Cox proportional hazards models. Results Current use of fish oil was associated with reduced risk of breast cancer (HR 0.68, 95% CI: 0.50-0.92). 10-year average use was suggestive of reduced risk (p-trend=0.09). These results held for ductal but not lobular cancers. The remaining specialty supplements were not associated with breast cancer risk: specifically, use of supplements sometimes taken for menopausal symptoms (black cohosh, dong quai, soy, or St. John’s wort) was not associated with risk. Conclusions Further study of fish oil for possible chemoprevention against breast cancer is warranted. Impact Until these results are replicated, fish oil should not be promoted for reduction of breast cancer risk. PMID:20615886

  12. A three phase load flow algorithm for Shipboard Power Systems

    E-print Network

    Medina-Calder?on, M?onica M

    2003-01-01

    in computing the steady state operation values. For my father, mother, and sister Angelica. Thank you for your constant support, never ending love, and everything you have given me, ACKNOWLEDGEMENTS I thank God for all of the blessings he has given me... throughout my life and ask that he continue to remain the center of my life. I thank my parents for their sacrifice in supporting my entire education. Dad, Mom, and Angelica: thank you for supporting me in all my endeavors, providing for my needs, giving...

  13. Experimental evidence of ballistic transport in cylindrical gate-all-around twin silicon nanowire metal-oxide-semiconductor

    E-print Network

    Hwang, Sung Woo

    Advanced Technology Development Team 1, R&D Center, Samsung Electronics Co., San 24, Nongseo-Dong, Giheung-functional Devices and School of Electrical Engineering, Korea University, 5-1 Anam-Dong, Sungbuk-Gu, Seoul, 136 the channel. Earlier, such perfect bal- listicity and conductance quantization at cryogenic tempera- tures

  14. XINS: The Anatomy of an Indoor Positioning and Navigation Architecture

    E-print Network

    Chang, Edward Y.

    .com Qingxuan Yang qingxuan@google.com Guanfeng Li ligf@google.com Edward Y. Chang edchang@google.com Dong Wang wangdong@google.com Chengu Wang wangchengu@gmail.com Hang Qu quhang@google.com Pei Dong dongpei@google.com Faen Zhang zhangfaen@google.com Dept. of Computer Science and Technology IIIS Google Research

  15. XINS: The Anatomy of an Indoor Positioning and Navigation Architecture

    E-print Network

    Tang, Pingzhong

    .com Qingxuan Yang qingxuan@google.com Guanfeng Li ligf@google.com Edward Y. Chang edchang@google.com Dong Wang wangdong@google.com Chengu Wang wangchengu@gmail.com Hang Qu quhang@google.com Pei Dong dongpei@google.com Faen Zhang zhangfaen@google.com Google Research, Beijing, China Dept. of Computer Science

  16. Centrality and pseudorapidity dependence of charged hadron production at intermediate p(T) in Au plus Au collisions at root s(NN)=130 GeV 

    E-print Network

    Adams, J.; Aggarwal, MM; Ahammed, Z.; Amonett, J.; Anderson, BD; Arkhipkin, D.; Averichev, GS; Bai, Y.; Balewski, J.; Barannikova, O.; Barnby, LS; Baudot, J.; Bekele, S.; Belaga, VV; Bellwied, R.; Berger, J.; Bezverkhny, BI; Bharadwaj, S.; Bhatia, VS; Bichsel, H.; Billmeier, A.; Bland, LC; Blyth, CO; Bonner, BE; Botje, M.; Boucham, A.; Brandin, A.; Bravar, A.; Bystersky, M.; Cadman, RV; Cai, XZ; Caines, H.; Sanchez, MCD; Carroll, J.; Castillo, J.; Cebra, D.; Chaloupka, P.; Chattopdhyay, S.; Chen, HF; Chen, Y.; Cheng, J.; Cherney, M.; Chikanian, A.; Christie, W.; Coffin, JP; Cormier, TM; Cramer, JG; Crawford, HJ; Das, D.; Das, S.; de Moura, MM; Derevschikov, AA; Didenko, L.; Dietel, T.; Dong, WJ; Dong, X.; Draper, JE; Du, F.; Dubey, AK; Dunin, VB; Dunlop, JC; Mazumdar, MRD; Eckardt, V.; Edwards, WR; Efimov, LG; Emelianov, V.; Engelage, J.; Eppley, G.; Erazmus, B.; Estienne, M.; Fachini, P.; Faivre, J.; Fatemi, R.; Fedorisin, J.; Filimonov, K.; Filip, P.; Finch, E.; Fine, V.; Fisyak, Y.; Foley, KJ; Fomenko, K.; Fu, J.; Gagliardi, Carl A.; Gans, J.; Ganti, MS; Gaudichet, L.; Geurts, F.; Ghazikhanian, V.; Ghosh, P.; Gonzalez, JE; Grachov, O.; Grebenyuk, O.; Grosnick, D.; Guertin, SM; Gupta, A.; Gutierrez, TD; Hallman, TJ; Hamed, A.; Hardtke, D.; Harris, JW; Heinz, M.; Henry, TW; Hepplemann, S.; Hippolyte, B.; Hirsch, A.; Hjort, E.; Hoffmann, GW; Huang, HZ; Huang, SL; Hughes, EW; Humanic, TJ; Igo, G.; Ishihara, A.; Jacobs, P.; Jacobs, WW; Janik, M.; Jiang, H.; Jones, PG; Judd, EG; Kabana, S.; Kang, K.; Kaplan, M.; Keane, D.; Khodyrev, VY; Kiryluk, J.; Kisiel, A.; Kislov, EM; Klay, J.; Klein, SR; Klyachko, A.; Koetke, DD; Kollegger, T.; Kopytine, M.; Kotchenda, L.; Kramer, M.; Kravtsov, P.; Kravtsov, VI; Krueger, K.; Kuhn, C.; Kulikov, AI; Kumar, A.; Kunz, CL; Kutuev, RK; Kuznetsov, AA; Lamont, MAC; Landgraf, JM; Lange, S.; Laue, F.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lehocka, S.; LeVine, MJ; Li, C.; Li, Q.; Li, Y.; Lindenbaum, SJ; Lisa, MA; Liu, F.; Liu, L.; Liu, QJ; Liu, Z.; Ljubicic, T.; Llope, WJ; Long, H.; Longacre, RS; Lopez-Noriega, M.; Love, WA; Lu, Y.; Ludlam, T.; Lynn, D.; Ma, GL; Ma, JG; Ma, YG; Magestro, D.; Mahajan, S.; Mahapatra, DP; Majka, R.; Mangotra, LK; Manweiler, R.; Margetis, S.; Markert, C.; Martin, L.; Marx, JN; Matis, HS; Matulenko, YA; McClain, CJ; McShane, TS; Meissner, F.; Melnick, Y.; Meschanin, A.; Miller, ML; Milosevich, Z.; Minaev, NG; Mironov, C.; Mischke, A.; Mishra, D.; Mitchell, J.; Mohanty, B.; Molnar, L.; Moore, CF; Mora-Corral, MJ; Morozov, DA; Morozov, V.; Munhoz, MG; Nandi, BK; Nayak, TK; Nelson, JM; Netrakanti, PK; Nikitin, VA; Nogach, LV; Norman, B.; Nurushev, SB; Odyniec, G.; Ogawa, A.; Okorokov, V.; Oldenburg, M.; Olson, D.; Pal, SK; Panebratsev, Y.; Panitkin, SY; Pavlinov, AI; Pawlak, T.; Peitzmann, T.; Perevoztchikov, V.; Perkins, C.; Peryt, W.; Petrov, VA; Phatak, SC; Picha, R.; Planinic, M.; Pluta, J.; Porile, N.; Porter, J.; Poskanzer, AM; Potekhin, M.; Potrebenikova, E.; Potukuchi, BVKS; Prindle, D.; Pruneau, C.; Putschke, J.; Rai, G.; Rakness, G.; Raniwala, R.; Raniwala, S.; Ravel, O.; Ray, RL; Razin, SV; Reichhold, D.; Reid, JG; Renault, G.; Retiere, F.; Ridiger, A.; Ritter, HG; Roberts, JB; Rogachevskiy, OV; Romero, JL; Rose, A.; Roy, C.; Ruan, L.; Sahoo, R.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Savin, I.; Sazhin, PS; Schambach, J.; Scharenberg, RP; Schmitz, N.; Schroeder, LS; Schweda, K.; Seger, J.; Seyboth, P.; Shahaliev, E.; Shao, M.; Shao, W.; Sharma, M.; Shen, WQ; Shestermanov, KE; Shimanskiy, SS; Simon, F.; Singaraju, RN; Skoro, G.; Smirnov, N.; Snellings, R.; Sood, G.; Sorensen, P.; Sowinski, J.; Speltz, J.; Spinka, H. M.; Srivastava, B.; Stadnik, A.; Stanislaus, TDS; Stock, R.; Stolpovsky, A.; Strikhanov, M.; Stringfellow, B.; Suaide, AAP; Sugarbaker, E.; Suire, C.; Sumbera, M.; Surrow, B.; Symons, TJM; Szanto de Toledo, A.; Szarwas, P.; Tai, A.; Takahashi, J.; Tang, AH; Tarnowsky, T.; Thein, D.; Thomas, JH; Timoshenko, S.; Tokarev, M.; Trainor, TA; Trentalange, S.; Tribble, Robert E.; Tsai, O.; Ulery, J.; Ullrich, T.; Underwood, DG; Urkinbaev, A.; Van Buren, G.; Vander Molen, AM; Varma, R.; Vasilevski, IM; Vasiliev, AN; Vernet, R.; Vigdor, SE; Viyogi, YP; Vokal, S.; Vznuzdaev, M.; Waggoner, B.; Wang, F.; Wang, G.; Wang, G.; Wang, XL; Wang, Y.; Wang, Y.; Wang, ZM; Ward, H.; Watson, JW; Webb, JC; Wells, R.; Westfall, GD; Wetzler, A.; Whitten, C.; Wieman, H.; Wissink, SW; Witt, R.; Wood, J.; Wu, J.; Xu, N.; Xu, Z.; Xu, Z.; Yamamoto, E.; Yepes, P.; Yurevich, VI; Zanevsky, YV; Zhang, H.; Zhang, WM; Zhang, ZP; Zolnierczuk, PA; Zoulkarneev, R.; Zoulkarneeva, Y.; Zubarev, AN; STAR Collaboration.

    2004-01-01

    . Chikanian,47 W. Christie,3 J. P. Coffin,17 T. M. Cormier,45 J. G. Cramer,44 H. J. Crawford,5 D. Das,42 S. Das,42 M. M. de Moura,34 A. A. Derevschikov,30 L. Didenko,3 T. Dietel,13 W. J. Dong,7 X. Dong,35 J. E. Draper,6 F. Du,47 A. K. Dubey,14 V. B. Dunin,11...

  17. 2 An assessment of the seasonal mixed layer salinity budget 3 in the Southern Ocean

    E-print Network

    2 An assessment of the seasonal mixed layer salinity budget 3 in the Southern Ocean 4 Shenfu Dong,1 the mixed layer salinity budget in the Southern Ocean. 25 Citation: Dong, S., S. L. Garzoli, and M. Baringer (2009), An assessment of the seasonal mixed layer salinity budget in the Southern 26 Ocean, J. Geophys

  18. 76 FR 56796 - In the Matter of Certain Devices for Improving Uniformity Used in a Backlight Module and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ...upon which this notice of investigation shall be served: (a) The...served: LG Corporation, LG Twin Towers, 20 Yeouido-dong...LG Electronics, Inc., LG Twin Towers, 20 Yeouido-dong...The Office of Unfair Import Investigations, U.S. International...

  19. Improved fluorescence-enhanced optical imaging and tomography by enhanced excitation light rejection 

    E-print Network

    Hwang, Kil Dong

    2009-05-15

    IMPROVED FLUORESCENCE-ENHANCED OPTICAL IMAGING AND TOMOGRAPHY BY ENHANCED EXCITATION LIGHT REJECTION A Dissertation by KIL DONG HWANG Submitted... IMPROVED FLUORESCENCE-ENHANCED OPTICAL IMAGING AND TOMOGRAPHY BY ENHANCED EXCITATION LIGHT REJECTION A Dissertation by KIL DONG HWANG Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment...

  20. 76 FR 10329 - Initiation of Antidumping and Countervailing Duty Administrative Reviews and Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ...Ltd. Wuxi City DeRui Seamless Steel Pipe Co. Wuxi City DongQun Steel Tube Co. Wuxi Dingyuan Precision Cold-Drawn Steel Pipe Co. Wuxi Erquan Special Steel...Steel Tube Wuxi Zhen Dong Steel Pipe Works Wuxi Zhenda Special Steel Tube...

  1. On MEMS equation with fringing field Juncheng Wei1

    E-print Network

    Wei, Jun-cheng

    On MEMS equation with fringing field Juncheng Wei1 , Dong Ye2 1 Department of Mathematics Universit´e de Metz, 57045 Metz, France. E-mail address: dong.ye@univ-metz.fr Abstract We consider the MEMS case (i.e. = 0) and confirms the simulations in [14, 11]. Key words. MEMS, rupture, fringing field

  2. Wave Touch: Educational Game on Interactive Tabletop with Water Simulation

    E-print Network

    Paris-Sud XI, Université de

    , Kiwon Yeom1 , DongWook Yoon1 , Dong-young Kim2 , JungHyun Han2 and Ji-Hyung Park1 1 Intelligence description with a height- field representation. The conservative Saint-Venant equations can be written as Where h is the height of the fluid above zero-level, U is the velocity of the fluid in the horizontal

  3. Ultrawideband photonic crystal fiber coupler for multiband optical imaging system

    E-print Network

    Chen, Zhongping

    Department of Physics, Chosun University, 375 Seosuk-dong, Dong-gu, Gwangju 501-759, Korea 3 Beckman LaserUltrawideband photonic crystal fiber coupler for multiband optical imaging system Seon Young Ryu,1 March 2010 We report a photonic crystal fiber (PCF) coupler having an ultrawide spectral bandwidth

  4. Effects of food distribution on the habitat usage of a female brown bear Ursus arctos yesoensis in a beech-forest zone of northernmost Japan

    Microsoft Academic Search

    Fuyuki Nomura; Seigo Higashi

    2000-01-01

    The habitat usage of a female brown bear, Ursus arctos yesoensis L., was studied in relation to the distribution of food plants in a beech-forest zone of Hokkaido, Japan. The bear’s habitat usage was correlated with the distribution of the plant Angelica ursina (Rupt.) Maxim. in summer. In spring the bear preferred Petasites japonicus (Sieb. et Zucc.) Maxim. and Heracleum

  5. Molecular systematics of Old World Apioideae (Apiaceae): relationships among some members of tribe Peucedaneae sensu lato, the placement of several island-endemic species, and resolution within the apioid superclade

    Microsoft Academic Search

    Stephen R. Downie; Mark F. Watson; Krzysztof Spalik; Deborah S. Katz-Downie

    2000-01-01

    Comparative sequencing of the two internal transcribed spacer regions of nuclear ribosomal DNA was car- ried out to examine evolutionary relationships among representatives of Old World Apiaceae (Umbelliferae) subfamily Apioideae. Emphasis was placed on delimiting groups within the previously designated apioid superclade and clarifying relationships within and among the peucedanoid genera Angelica, Ferula, Heracleum, and Peucedanum. These spacer data, and

  6. Proceedings of the 2009 Industrial Engineering Research Conference Technology Assessment for an Inventory Management Process in a

    E-print Network

    Rossetti, Manuel D.

    for an Inventory Management Process in a Hospital Unit Angelica Burbano, Behlul Saka, Ronald Rardin, Manuel a technological alternative. This paper studies the impact of Auto ID DC technologies on the inventory management Technologies, barcodes, RFID, hospital unit inventory management, quantitative modeling 1. Introduction Auto ID

  7. In vitro anti-microbial and in vivo cytokine modulating effects of different prepared Chinese herbal medicines

    Microsoft Academic Search

    Shyh-Jye Lin; Chung-Shih Chen; Shih-Shen Lin; Ming-Yung Chou; Hung-Che Shih; I-Pang Lee; Chia-Tze Kao; Chuan-Chen Ho; Fong-Lin Chen; Yung-Chyuan Ho; Kuang-Hui Hsieh; Chi-Ruei Huang; Chi-Chiang Yang

    2006-01-01

    The toxicity, antimicrobial and cytokine modulating effects of herbal medicines in treating periodontal diseases were evaluated in this study. Using the broth dilution method and disc agar diffusion test, in individual and combined decocted preparations, different concentrations of Ching–Wei–San and its individual herbal components, Coptidis rhizoma, Angelicae sinensis radix, Rehmanniae radixet rhizom, Moutan radicis cortex, and Cimicifuga foetida, were tested

  8. Primer Apellido Segundo Apellido Nombre Monto ACUAPAN HERNANDEZ JAVIER 17,000.00$

    E-print Network

    ,037.00$ DOMINGUEZ VICTORIA MAGDALENA 8,074.00$ DUARTE HERNANDEZ ANGELICA MARIA 9,584.00$ DUQUE MARTINEZ HECTOR SANCHEZ ABDI 7,800.00$ ESCALONA VARGAS DIANA IRAZU 9,584.00$ ESCAMILLA ALVARADO CARLOS 9,584.00$ ESCAMILLA

  9. The anticoagulant ability of ferulic acid and its applications for improving the blood compatibility of silk fibroin

    Microsoft Academic Search

    Song Wang; Zhen Gao; Xiaomeng Chen; Xiaojie Lian; Hesun Zhu; Jun Zheng; Lizhong Sun

    2008-01-01

    The hemocompatibility of silk fibroin (SF) was improved with ferulic acid (FA) by graft polymerization. Ferulic acid is an active ingredient of many Chinese herbal medicines, such as Chuanxiong (Rhizoma ligustici wallichii), Danggui (Angelica sinensis) and Awei (Asafoetida giantfennel), which have been used to treat cardiovascular diseases by Chinese physicians for thousands of years. The inhibitory functions of FA on

  10. doi:10.1152/physiol.00012.200722:252-260, 2007.Physiology Nicoloaas C. Schaper and Coen D. A. Stehouwer

    E-print Network

    Cooper, Robin L.

    and Hypertension Mechanism in the Pathogenesis of Obesity-Associated Microvascular Dysfunction in Obesity Francesca Schinzari, Manfredi Tesauro, Valentina Rovella, Angelica Galli, Nadia Mores, Ottavia obesity, Peter W. de Leeuw, Erik H. Serné, Yvo M. potential mechanism in the pathogenesis of obesity

  11. Nonlinear Programming Approaches for Efficient Large-Scale Parameter Estimation with Applications in Epidemiology

    E-print Network

    Word, Daniel Paul

    2013-07-09

    into chemical engineering during my rst year of graduate school. Sean, Angelica Mann, and I entered the research group at the same time, and I am thankful for the countless hours we have spent learning together. I am grateful for the nancial support of my...

  12. Assessment of Inundation Risk from Sea Level Rise and Storm Surge in Northeastern Coastal National Parks

    E-print Network

    Wang, Y.Q. "Yeqiao"

    Assessment of Inundation Risk from Sea Level Rise and Storm Surge in Northeastern Coastal National.S.A. Angelica.murdukhayeva@gmail.com National Park Service Northeast Region 15 State Street Boston, MA 02109, U of inundation risk from sea level rise and storm surge in northeastern coastal national parks. Journal

  13. Distribution pattern and conservation of threatened medicinal and aromatic plants of Central Himalaya, India

    Microsoft Academic Search

    L. S. Kandari; K. S. Rao; R. K. Maikhuri; G. Kharkwal; K. Chauhan; C. P. Kala

    A study was conducted to examine the distribution pattern of four rhizomatous medicinal and aromatic plant species (MAPs)\\u000a viz., Angelica glauca, Pleurospermum angelicoides, Rheum emodi and Arnebia benthamii in different forest stands in Central Himalaya. Results show that A. glauca and P. angelicoides had a higher (50%) frequency at Chipkoan, Garpak and Phagati forest, R. emodi had a higher (60%)

  14. Ali Abdelhadi Nii Seth Obodai-Sai Aborhey

    E-print Network

    Sinnamon, Gordon J.

    Michael James Adams Oluwatola Oluwafunmike Afolabi Hanga Agoston Andrew John Peter Akelaitis Tuba Aksoy Kenneth Bocking Jessica Elaine Bodig Michael Larry Bodnar Froeydis Margrethe Boee Lisa Alexandra Warren Cook Angelica Cornacchio Anne Costello Rebecca K. Cowan Rebecca Lynne Coward Aaron Richard Cox Amy

  15. HonorsConvocation TexasTechUniversity

    E-print Network

    Gelfond, Michael

    of Engineering #12;CUM LAUDE Andrew Michael Alleman Angelica Arratia Delgadillo Hannah Rachelle Boland Madeline Leigh Carr Joseph Michael Carroll Cody Ross Collins Colton David-Wood Cromer BryceTruman Eckeberger Rebecca Scheers Michael David Sees JeffreyWallace Shed Winnie Chantal Simo Ibouanga Steven R Spratford

  16. ig research into the tiny world of nanotechnology received a giant boost with the establishment of the Russell Berrie Nanotechnology Institute (RBNI) at the

    E-print Network

    Rimon, Elon

    B ig research into the tiny world of nanotechnology received a giant boost with the establishment of the Russell Berrie Nanotechnology Institute (RBNI) at the Technion. "The Technion's ranking as a world leader in nanotechnology strongly influenced our decision," said Angelica Berrie, president of the Russell Berrie

  17. Thursday, Nov 20, 2014 12 pm 2pm

    E-print Network

    application 62/021,430, S. Biswas, Bo Dong, and R. Gallant, System and Methods for a Smart Water Bottle C. Algorithms are developed for detecting various types of swallowing events including for solid and liquid

  18. 78 FR 51209 - Certain Tires and Products Containing Same Notice of Receipt of Complaint; Solicitation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-20

    ...Ltd. of China; Doublestar Dong Feng Tyre Co., Ltd. of China; Shandong Yongtai Chemical Group Co., Ltd. of China; MHT Luxury Alloys of CA; Wheel Warehouse, Inc. of CA; Shandong Linglong Tyre Co., Ltd. of China; Dunlap & Kyle Company,...

  19. Review of Korean Dacetini (Hymenoptera: Formicidae: Myrmicinae)

    E-print Network

    Villemant, Claire

    , Formicidae, Korea INTRODUCTION The Dacetini is a tribe of ants that are all predators, most of them smallReview of Korean Dacetini (Hymenoptera: Formicidae: Myrmicinae) Dong-Pyeo LYU, Byeong-MOON CHOI1

  20. 884 IEEETRANSACTIONS ON COMMUNICATIONS, VOL. 42, NO. 21314, FEBRUARY/MARCH/APRIL 1994 ancement of Direct-Sequence Spread-Spectrum.Packet Radio

    E-print Network

    Yao, Yu-Dong

    of Direct-Sequence Spread-Spectrum.Packet Radio Networks by Adaptive Power Control Asrar Sheikh,Yu-Dong Yao and Shixin Clneng Absti-ucf- This paper investigates the performance of direct- sequence spread-spectrum

  1. 77 FR 11587 - Certain Dimmable Compact Fluorescent Lamps and Products Containing Same; Institution of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ...Investigation Pursuant to 19 U.S.C. 1337 AGENCY: U.S. International Trade Commission...Electronics Co., Ltd., No. 139 Wang Dong South Road E, Si Jing song...Chief Administrative Law Judge, U.S. International Trade...

  2. Predictive Link Trigger Mechanism for Seamless Handovers in Heterogeneous Wireless Networks

    E-print Network

    -Jo Yoo* , David Cypher** , Nada Golmie** * Inha University, 253, Yonghyun-Dong, Nam-Gu, Incheon, 402@inha.ac.kr, david.cypher@nist.gov, nada.golmie@nist.gov Abstract Effective and timely link-layer trigger mechanisms

  3. Characterization of Protein Structure and Function at Genome Scale Using a Computational Prediction Pipeline

    E-print Network

    Prediction Pipeline Dong Xu1 *, Dongsup Kim1 , Phuongan Dam1 , Manesh Shah1 , Edward C. Uberbacher1 Pipeline. Keywords: protein structure prediction; fold recognition; threading; genome annotation; structure and integrates systematic data generation, computational data interpretation, and experimental validation

  4. OPERATIONS RESEARCH Vol. 54, No. 5, SeptemberOctober 2006, pp. 933950

    E-print Network

    Armbruster, Dieter

    Department of Mathematics, Arizona State University, Tempe, Arizona 85287-1804, ringhofer@asu.edu Karl Kempf, karl.g.kempf@intel.com Tae-Chang Jo Mathematics Department, Inha University, 253, Yonghyun-Dong, Nam

  5. Applied stress controls the production of nano-twins in coarse-grained metals

    E-print Network

    Zhu, Yuntian T.

    University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, South Korea 4 Australian Centre for Microscopy of Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina 27695, USA

  6. 77 FR 12235 - Wooden Bedroom Furniture From the People's Republic of China: Initiation of Administrative Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ...Furniture Ltd.; * Fortune Glory Industrial Ltd. (H. K. Ltd...Dong Guan) Co., Ltd.* World Design International Co...of Yangchun Yeh Brothers World Trade, Inc.* Yihua Timber...Ltd.* Zhangzhou Guohui Industrial & Trade Co. Ltd.*...

  7. The Chemical Nature of Scaritoxin YONG-GOE JOH and PAUL J. SCHEUER

    E-print Network

    and Nutrition, Dong-A University, Pusan, Korea. curred to us that these two chromato- graphic forms of ciguatoxin might be identical with the scaritoxin-ciguatoxin pair recognized in the flesh of parrot- fish

  8. 76 FR 5824 - In the Matter of Certain Mobile Telephones and Modems; Notice of Investigation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    ...For the purpose of the investigation so instituted, the following...upon which this notice of investigation shall be served: (a) The...Electronics, Inc., LG Twin Towers, 20 Yeouido-dong...attorney, party to this investigation, is Mareesa A....

  9. FNANO12 Table of Contents Table of Contents

    E-print Network

    Reif, John H.

    . . . . . . . . . . . . . . . . . . . . . . . . . 4 Steven Chirieleison, Peter Allen, Andrew McIver, Andrew Ellington and Xi Chen Posters: Top Lieberman, Kyoung Nan Kim, Je Moon Yun, Ju Young Kim, Dong Ok Shin, Won Jun Lee, Sun Hwa Lee and Sang Ouk

  10. Profilin Is Essential for Tip Growth in the Moss Physcomitrella patens W

    E-print Network

    Bezanilla, Magdalena

    are required to properly organize F-actin. INTRODUCTION Tip growth in plants is required for the development ADF/cofilin inhibits pollen tube and root hair elongation (Dong et al., 2001; Chen et al., 2002

  11. PREPARED FORTHE U.S. DEPARTMENT OF ENERGY, UNDER CONTRACT DEAC0276CH03073

    E-print Network

    between pulses. CAMAC NSTX Instrumentation &Controllers NSTXSpectroscopyData &VMS Analysis X devices supported. CAMAC NSTX Instrumentation &Controllers NSTXSpectroscopyData &VMS Analysis X Control System Sichta, Dong, Oliaro, and Roney December 2001 #12; PPPL Reports Disclaimer report prepared

  12. Hybridizing VNS and path-relinking on a particle swarm framework ...

    E-print Network

    Wagner Emanoel Costa; Marco César Goldbarg; Elizabeth G. Goldbarg

    2012-04-12

    search method [5], iterated greedy approach [22], genetic algorithms [33, 31, 7], ant colonies. [24, 34], particle ...... Computers & Industrial Engineering, 59(4):778 – 785, 2010. [5] DONG, X ... CHINE AND HUMAN SCIENCE, p. 39 – 43, 1995.

  13. 76 FR 61076 - Initiation of Antidumping and Countervailing Duty Administrative Reviews and Requests for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ...Food Company, Ltd. QVD Dong Thap Food Co., Ltd. Saigon-Mekong Fishery Co., Ltd. (SAMEFICO) Southern Fishery Industries...Region International Co., Ltd. Richard Hung Ent. Co. Ltd. River Display Ltd. Rizhao Changxing Nail-Making Co., Ltd....

  14. An asymptotic inclusion speed for the Douglas-Rachford splitting ...

    E-print Network

    2014-12-29

    Keywords Monotone inclusion · Douglas-Rachford splitting · Proximal point ..... Lawrence J., Spingarn J.E.: On fixed points of non-expansive piecewise ... Dong Y.D.: Comments on ”The proximal point algorithm revisited”. J. Optim. Theory.

  15. Austenite in Transformation-Induced Plasticity Steel Subjected to Multiple Isothermal Heat Treatments

    E-print Network

    Duong, Van Tuan; Song, You Young; Park, Kyong-Su; Bhadeshia, H. K. D. H.; Suh, Dong-Woo

    2014-06-18

    are necessary are also discussed. Keywords: austenite stability, transformation-induced plasticity, bainite, multiple heat treatments, mechanism of bainite transformation Email address: dongwoo1@postech.ac.kr (Dong-Woo Suh) Preprint submitted to Metallurgical...

  16. CHRONOS: Facilitating History Discovery by Linking Temporal Records

    E-print Network

    Greenberg, Albert

    -Bicocca pei.li@disco.unimib.it Haidong Wang Nankai University alphardwang@gmail.com Christina Tziviskou University of Milan-Bicocca christina.tziviskou@disco.unimib.it Xin Luna Dong AT&T Labs-Research lunadong

  17. Technical Design Update to Proposal for a Large Area

    E-print Network

    Llope, William J.

    , A. Tai University of California - Los Angeles, Los Angeles, CA 90095 Hongfang Chen, Xin Dong, Cheng Li, Haidong Liu, Ming Shao, Yongjie Sun, Xiaolian Wang, Jian Wu, Ziping Zhang, Yane Zhao University

  18. Pharmaceutical Supply Chain

    E-print Network

    Nagurney, Anna

    Engineering University of Hartford, West Hartford, CT 06117 #12;Pharmaceutical Supply Chain NetworksPharmaceutical Supply Chain Networks with Outsourcing Nagurney, Li, and Nagurney Pharmaceutical Supply Chain Networks with Outsourcing Under Price and Quality Competition Anna Nagurney1, Dong (Michelle

  19. From Sensor Network To Social Network A Study On The Energy Impact In Buildings

    E-print Network

    Pratt, Vaughan

    , Bing Dong2 , Latanya Sweeney1 Data Privacy Lab, School of Computer Science1 Center for Building and detecting activities of daily living such as cooking, eating, etc., Youngblood et al. [16] introduced a new

  20. Joostella marina gen. nov., sp. nov., a novel member of the family Flavobacteriaceae isolated from the

    E-print Network

    Bae, Jin-Woo

    ). Cell biomass for DNA extraction and for fatty acid methyl ester and quinone analyses was obtained from by Dong & Cai (2001) by using media prepared with artificial seawater (per litre distilled water: 23.5 g

  1. Mills, E.1, Morris, M.R.1, Lang, C.C.2, Wang, Q.D.3, Dong, H.3, Mauerhan, J.1, Stolovy, S.4, Cotera, A.5, Muno, M.4, Calzetti, D.3, Ramirez, S.V.4, Schneider, G.6

    E-print Network

    Schneider, Glenn

    , particularly in the Sickle. Sheared dust clumps Filaments as Magnetic Rayleigh-Taylor Instabilities Plasma in this gas is due to a magnetic Rayleigh-Taylor instability. [1] Chuss, D.T., Davidson, J.A, Dotson, J- dicted by this model or observed in the Pleiades. · As dusty filaments are sheared by the gas

  2. The use of herbal medicines during breastfeeding: a population-based survey in Western Australia

    PubMed Central

    2013-01-01

    Background Main concerns for lactating women about medications include the safety of their breastfed infants and the potential effects of medication on quantity and quality of breast milk. While medicine treatments include conventional and complementary medicines, most studies to date have focused on evaluating the safety aspect of conventional medicines. Despite increasing popularity of herbal medicines, there are currently limited data available on the pattern of use and safety of these medicines during breastfeeding. This study aimed to identify the pattern of use of herbal medicines during breastfeeding in Perth, Western Australia, and to identify aspects which require further clinical research. Methods This study was conducted using a self-administered questionnaire validated through two pilot studies. Participants were 18 years or older, breastfeeding or had breastfed in the past 12 months. Participants were recruited from various community and health centres, and through advertising in newspapers. Simple descriptive statistics were used to summarise the demographic profile and attitudes of respondents, using the SPSS statistical software. Results A total of 304 questionnaires from eligible participants were returned (27.2% response rate) and analysed. Amongst the respondents, 59.9% took at least one herb for medicinal purposes during breastfeeding, whilst 24.3% reported the use of at least one herb to increase breast milk supply. Most commonly used herbs were fenugreek (18.4%), ginger (11.8%), dong quai (7.9%), chamomile (7.2%), garlic (6.6%) and blessed thistle (5.9%). The majority of participants (70.1%) believed that there was a lack of information resources, whilst 43.4% perceived herbal medicines to be safer than conventional medicines. Only 28.6% of users notified their doctor of their decision to use herbal medicine(s) during breastfeeding; 71.6% had previously refused or avoided conventional medicine treatments due to concerns regarding safety of their breastfed infants. Conclusions The use of herbal medicines is common amongst breastfeeding women, while information supporting their safety and efficacy is lacking. This study has demonstrated the need for further research into commonly used herbal medicines. Evidence-based information should be available to breastfeeding women who wish to consider use of all medicines, including complementary medicines, to avoid unnecessary cessation of breastfeeding or compromising of pharmacotherapy. PMID:24219150

  3. Presidio County State of the Community Reprort 

    E-print Network

    Xiao, Dong; Hwang, Jinuk; McCharen, Rob

    2015-01-01

    STATE OF THE COMMUNITY REPORT PRESIDIO COUNTY, TEXAS Dong Xiao|Jinuk Hwang|Rob McCharen Department of Landscape Architecture & Urban Planning State of the Community Report Presidio County, TX 1 Executive...PRESIDIO MARFA PRESIDIO COUNTY, TEXAS State of the Community Population Economy Housing Environment SWOT Analysis Department of Landscape Architecture & Urban Planning Jinuk Hwang | Robert McCharen | Dong Xiao Presidio County, TX Located...

  4. Recovery of Carboxylic Acids from Fermentation Broth via Acid Springing

    E-print Network

    Dong, Jipeng

    2010-01-14

    RECOVERY OF CARBOXYLIC ACIDS FROM FERMENTATION BROTH VIA ACID SPRINGING A Thesis by JIPENG DONG Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree... of MASTER OF SCIENCE December 2008 Major Subject: Chemical Engineering RECOVERY OF CARBOXYLIC ACIDS FROM FERMENTATION BROTH VIA ACID SPRINGING A Thesis by JIPENG DONG Submitted to the Office of Graduate Studies of Texas A...

  5. Eur. Phys. J. B 71, 339344 (2009) DOI: 10.1140/epjb/e2009-00225-1 Double-exchange model study of multiferroic RMnO3 perovskites

    E-print Network

    Tennessee, University of

    2009-01-01

    of multiferroic RMnO3 perovskites S. Dong, R. Yu, S. Yunoki, J.-M. Liu and E. Dagotto #12;Eur. Phys. J. B 71, 339-exchange model study of multiferroic RMnO3 perovskites S. Dong1,2,3,a , R. Yu1,2 , S. Yunoki4,5 , J.-M. Liu3 on the multiferroic RMnO3 perovskites are briefly reviewed at first. Using the double-exchange model, the realistic

  6. Subscriber access provided by POSTECH Library Chemistry of Materials is published by the American Chemical Society. 1155

    E-print Network

    Jo, Moon-Ho

    of Ge Nanowires from Ni#Cu Bulk Alloys Kibum Kang, Gil Ho Gu, Dong An Kim, Chan Gyung Park, and Moon-Organized Growth of Ge Nanowires from Ni-Cu Bulk Alloys Kibum Kang, Gil Ho Gu, Dong An Kim, Chan Gyung Park found that GeH4 precursors selectively and catalytically decompose into Cu within the Ni-Cu alloy matrix

  7. Inhibition of Trypanosoma cruzi growth by medical plant extracts

    Microsoft Academic Search

    G. R Schinella; H. A Tournier; J. M Prieto; J. L R??os; H Buschiazzo; A Zaidenberg

    2002-01-01

    This study describes the screening of extracts obtained from 18 plants and two fungi used in the Chinese and Mediterranean traditional medicines on epimastigote forms of Trypanosoma cruzi. The extracts were tested against epimastigote of T. cruzi Bra C15C2 clone in vitro at 27 °C and at a concentration of 250 ?g\\/ml in axenic culture. Angelica dahurica, A. pubescens, A.

  8. Simulation study of the effect of hydrodynamic forces on oil recovery 

    E-print Network

    Idrobo Hurtado, Eduardo Alejandro

    1992-01-01

    for entrapment. Hydrocarbons may be trapped under hydrodynamic conditions when the water in the aquifer is in motion. Hydrodynamically effected petroleum reservoirs are the result of ground water flow on the subsurface distribution of hydrocarbons. The relative... of entrapment was also investigated. DEDICATION To my wife Angela Maria and my daughter Maria Angelica for their undying love, support, and patience. To my parents: Eduardo Idrobo Mazorra y Maruja Hurtado de Idmbo. ACKNOWLEDGEMENTS I would like to thank...

  9. Identification and determination of the major constituents in Traditional Chinese Medicinal formula Danggui-Shaoyao-San by HPLC–DAD–ESI-MS\\/MS

    Microsoft Academic Search

    Linlin Chen; Jin Qi; Yan-xu Chang; Danni Zhu; Boyang Yu

    2009-01-01

    Danggui-Shaoyao-San (DSS), a famous traditional Chinese medicine formula consisting of six herbal medicines (Paeonia lactiflora, Angelica sinensis, Ligusticum chuanxiong, Poria cocos, Atractylodis macrocephalae and Rhizoma Alismatis), has been used as a classical gynecological remedy in China for centuries. However, its active substances have remained unknown. In this paper, an HPLC\\/DAD\\/ESI-MS\\/MS method was developed for the qualitative and quantitative analysis of

  10. News.

    E-print Network

    Dickson, Donald R., ed.

    2007-01-01

    NEWS 101 Proceedings of the Milton Society of America Radisson Plaza-Warwick Hotel, Philadelphia December 28, 2006 Secretary: A. C. Labriola, Dept. of English, Duquesne University, Pittsburgh, PA 15282 (E mail: Labriola@duq.edu) The officers... for President; Kristin Pruitt for Vice President; and William Shullenberger and Nicholas von Maltzahn for three-year membership (2007-2009) on the Executive Committee, suc- ceeding Gardner Campbell and Angelica Duran. 2. TREASURER?S REPORT. Benet indicated...

  11. The changing face of the healthcare market. Interview by Virginia Sowers.

    PubMed

    Stefoff, J

    1992-11-01

    Angelica CEO Jim Stefoff knows a good market opportunity when he sees one. And right now, the time is right for textile rental companies to make inroads into the small medical and dental office market that is emerging in the aftermath of the OSHA bloodborne pathogens ruling. But, Stefoff cautions, the industry must be in full compliance with OSHA regulations and able to provide the right delivery system and products. PMID:10122629

  12. Effect of Chinese Herbal Medicinal Ingredients on IL2 mRNA Levels of T Lymphocytes in Mice Measured Using Semiquantification RT-PCR

    Microsoft Academic Search

    Yue-feng CHU; Xin-min YAN; Xiang-rui LI; Yuan-liang HU

    2006-01-01

    In this study, the IL-2 mRNA levels of T lymphocytes in normal mice stimulated by nine Chinese herbal medicinal ingredients (CHMIs) were measured using Semiquantification reverse transcription polymerase chain reaction. The results showed that astragalus polysaccharide (APS), epimedium polysaccharide (EPS), Chinese angelica polysaccharide (CAPS), propolis flavone (PF), and astrogalosides (AS) promoted IL-2 mRNA levels in T lymphocytes in vitro and

  13. A CLASS OF ITERATIVE METHODS FOR SOLVING SADDLE POINT PROBLEMS

    E-print Network

    Bank, Randolph E.

    by the Office of Naval Research under contract N00014­ 82K­0197, by Avions Marcel Dassault, 78 Quai Marcel Aviation, 78 quai Marcel Dassault, 92214 St Cloud, France and by Direction des Recherches Etudes et

  14. A POSTERIORI ERROR ESTIMATES FOR THE STOKES PROBLEM RANDOLPH E. BANK y AND BRUNO D. WELFERT z

    E-print Network

    Bank, Randolph E.

    was supported by the Office of Naval Research under contract N00014­89J­ 1440, by Dassault Aviation, 78 quai, Arizona 85282. The work of this author was supported by Dassault Aviation, 78 quai Marcel Dassault, 92214

  15. Practice in photonics education and training

    NASA Astrophysics Data System (ADS)

    Zhang, Yong-Lin; Di, Hong-Wei; Zhong, Jingang

    2002-05-01

    Photonics and photon technology play an important role in information technology and life science in the 21st Century. Jinan University always devotes itself to the training of the technicians in optics and photonics. We have founded the system of undergraduate and postgraduate courses and also built up the photonics technology major lab of Guang Dong Education Bureau. The research involves the optoelectronics detection, the image processing, laser biological effects, optical communications, and so on. Jinan University works hard to promote the industrial application of photonics technology. Jinan University is making its great contribution to the construction of Photon Valley of Guang Dong Province.

  16. An update on antitumor activity of naturally occurring chalcones.

    PubMed

    Zhang, En-Hui; Wang, Ru-Feng; Guo, Shu-Zhen; Liu, Bin

    2013-01-01

    Chalcones, which have characteristic 1,3-diaryl-2-propen-1-one skeleton, are mainly produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora, Glycyrrhiza, Humulus, Scutellaria, Parartocarpus, Ficus, Dorstenia, Morus, Artocarpus, and so forth. They have become of interest in the research and development of natural antitumor agents over the past decades due to their broad range of mechanisms including anti-initiation, induction of apoptosis, antiproliferation, antimetastasis, antiangiogenesis, and so forth. This review summarizes the studies on the antitumor activity of naturally occurring chalcones and their underlying mechanisms in detail during the past decades. PMID:23690855

  17. Neuroprotective effects of Buyang Huanwu decoction on cerebral ischemia-induced neuronal damage.

    PubMed

    Mu, Qingchun; Liu, Pengfei; Hu, Xitong; Gao, Haijun; Zheng, Xu; Huang, Haiyan

    2014-09-01

    Among the various treatment methods for stroke, increasing attention has been paid to traditional Chinese medicines. Buyang Huanwu decoction is a commonly used traditional Chinese medicine for the treatment of stroke. This paper summarizes the active components of the Chinese herb, which is composed of Huangqi (Radix Astragali seu Hedysari), Danggui (Radix Angelica sinensis), Chishao (Radix Paeoniae Rubra), Chuanxiong (Rhizoma Ligustici Chuanxiong), Honghua (Flos Carthami), Taoren (Semen Persicae) and Dilong (Pheretima), and identifies the therapeutic targets and underlying mechanisms that contribute to the neuroprotective properties of Buyang Huanwu decoction. PMID:25368650

  18. [Analysis and identification of chemical constituents in Siwu decoction by UPLC-Q-TOF-MS(E)].

    PubMed

    Wang, Zhen-Fang; Zhao, Yang; Pang, Xu; Yu, He-Shui; Kang, Li-Ping; Gao, Yue; Ma, Bai-Ping

    2013-11-01

    This research analyzed the chemical constituents of Siwu decoction by UPLC-Q-TOF-MS(E). Base on the data of mass and related-literatures, 43 peaks were profiled and 25 compounds, which contain 8 monoterpene glycosides from Paeonia lactiflora and 13 phthalides from Rhizoma chuanxiong and Radix angelica sinensis mainly, were identified in both positive and negative mode respectively. Meanwhile, chemical constituents of water extract and 60% ethanol extract of Siwu decoction were compared by the principal constituent analysis with MarkerLynx software, which provides the basis for the active ingredients of Siwu decoction. PMID:24494558

  19. [Preparation and application on compound excipient of sodium stearyl fumarate and plasdone S-630].

    PubMed

    Jiang, Yan-Rong; Zhang, Zhen-Hai; Jia, Xiao-Bin

    2013-01-01

    The compound excipient containing sodium stearyl fumarate and plasdone S-630 was prepared by applying spray drying method. The basic physical properties of compound excipient were studied by solubility test, scanning electron microscope, differential scanning calorimeter, X-ray diffraction and Fourier transform infra-red spectroscopy. The effect of compound excipient on moisture absorption and ferulic acid in vitro dissolution of spray drying power of angelica were investigated. The results showed that the chemical constituents of compound excipient did not change before and after spray drying. The water soluble compound excipient can improve significantly moisture absorption and has application prospect. PMID:23600153

  20. Neuroprotective effects of Buyang Huanwu decoction on cerebral ischemia-induced neuronal damage

    PubMed Central

    Mu, Qingchun; Liu, Pengfei; Hu, Xitong; Gao, Haijun; Zheng, Xu; Huang, Haiyan

    2014-01-01

    Among the various treatment methods for stroke, increasing attention has been paid to traditional Chinese medicines. Buyang Huanwu decoction is a commonly used traditional Chinese medicine for the treatment of stroke. This paper summarizes the active components of the Chinese herb, which is composed of Huangqi (Radix Astragali seu Hedysari), Danggui (Radix Angelica sinensis), Chishao (Radix Paeoniae Rubra), Chuanxiong (Rhizoma Ligustici Chuanxiong), Honghua (Flos Carthami), Taoren (Semen Persicae) and Dilong (Pheretima), and identifies the therapeutic targets and underlying mechanisms that contribute to the neuroprotective properties of Buyang Huanwu decoction. PMID:25368650

  1. Antiproliferative constituents in Umbelliferae plants II. Screening for polyacetylenes in some Umbelliferae plants, and isolation of panaxynol and falcarindiol from the root of Heracleum moellendorffii.

    PubMed

    Nakano, Y; Matsunaga, H; Saita, T; Mori, M; Katano, M; Okabe, H

    1998-03-01

    Methanol extracts of 36 samples of 21 Umbelliferae plants were screened for polyacetylenic compounds using the ELISA for panaxytriol, and their antiproliferative activity was checked by MTT assay using the tumor cell lines MK-1, HeLa and B16F10. The presence of antiproliferative polyacetylenes was suggested in Angelica acutiloba (fruit), Anethum graveolens (root), Bupleurum rotundifolium (fruit), Carum carvi (fruit and root), Coriandrum sativum (fruit), Cryptotaenia japonica (leaf), Glehnia littoralis (fruit), Heracleum moellendorffii (root) and Torilis japonica (fruit). Panaxynol and falcarindiol were successfully isolated from the root of Heracleum moellendorffii as antiproliferative polyacetylenes. PMID:9556156

  2. [A comparison of anti-arrhythmic effects of four kinds of rhizoma seu radix Nomopterygii].

    PubMed

    Zhu, X; Chu, R

    1990-06-01

    Experiments were conducted to compare the anti-arrhythmic effects of the four kinds of Qianghuo(Notopterygium incisum; N. forbesii; Pleurospermum rivulorum; Angelica silvestris). It has been found that all the four kinds of Qianghuo can antagonize arrhythmia induced by aconitine. Notopterygium incisum can prolong the ventricular vibration induced by CaCl2 and Pleurospermum rivulorum can prolong the ventricle stop induced by BaCl2. Thus Qianghuo can be used as a sedative and anti-arrhythmic drug. PMID:2206391

  3. Extracellular calmodulin-binding proteins in plants: purification of a 21-kDa calmodulin-binding protein

    Microsoft Academic Search

    Tang Jun; Wu Shupin; Bai Juan; Sun Daye

    1996-01-01

    A 21-kDa calmodulin (CaM)-binding protein and a 19-kDa calmodulin-binding protein were detected in 0.1 M CaCl2 extracts of Angelica dahurica L. suspension-cultured cells and carrot (Daucus carota L.) suspension-cultured cells, respectively, using a biotinylated cauliflower CaM gel-overlay technique in the presence of 1 mM Ca2+. No bands, or very weak bands, were shown on sodium dodecyl sulfate-polyacrylamide gel electrophoresis gels

  4. [Studies on chemical protectors against radiation. XXVI. Protective effect of various extracts on crude drugs on skin injury induced by X-irradiation].

    PubMed

    Sato, Y; Ohta, S; Sakurai, N; Shinoda, M

    1989-02-01

    The protective potency against skin injury on mice induced by X-irradiation was studied by use of 72 extracts of crude drugs. The protective potency was determined according to the degrees on skin injury after irradiation of 1100R, 30 k Vp soft X-ray. As a result of these study, 16 kinds of crude drugs such as Rosae Fructus, Aloe arborescens (Herba), Citri Leiocarpae Exocarpium, Schizonepetae Spica, Evodiae Fructus, Bupleuri Radix, Corni Fructus, Perillae Herba, Anemarrhenae Rhizoma, Menthae Herba, Trapae Fructus, Angelicae Dahuricae Radix, Sinomeni Caulis et Rhizoma, Ephedrae Herba, Acer nikoense (Cortex), Forsythiae Fructus, revealed protective potencies on skin injury. PMID:2746469

  5. MRA Based Wavelet Frames and Applications: Image Segmentation and Surface Reconstruction

    E-print Network

    Zakharov, Vladimir

    MRA Based Wavelet Frames and Applications: Image Segmentation and Surface Reconstruction Bin Dong1 Kent Ridge Road, Singapore, 119076 ABSTRACT Theory of wavelet frames and their applications to image restoration problems have been extensively studied for the past two decades. The success of wavelet frames

  6. 3.4 Wavelet Denoising for Image Enhancement SBC Laboratories

    E-print Network

    Rajashekar, Umesh

    3.4 Wavelet Denoising for Image Enhancement Dong Wei SBC Laboratories Austin, TX 78759 Umesh. Recently, wavelet-based denoising techniques have been recognized as powerful tools for denois- ing. Different from those filtering-based classical methods, wavelet-based methods can be viewed as transform

  7. IMAGE RESTORATION: TOTAL VARIATION, WAVELET FRAMES, AND BEYOND

    E-print Network

    Soatto, Stefano

    IMAGE RESTORATION: TOTAL VARIATION, WAVELET FRAMES, AND BEYOND JIAN-FENG CAI, BIN DONG, STANLEY]) are well established and effective for image restoration, as well as many other applications, while wavelet restoration, including image denoising, deblurring, inpainting, computed tomography, etc., is one of the most

  8. A Study on the Development of Mobile Based SNS-UCC Writing Tool

    E-print Network

    Paris-Sud XI, Université de

    Myung University 7 HongJi-Dong Jongno-Gu, Seoul, Korea Ph.D. Course, Dept of Game, Graduate School°, Division of Digital Media, College of Computer Software & Digital Media {hs4k2@naver.com°, rhee219@smu.ac.kr} Abstract is the many time and efforts needed in learning the using method. PC internet based UCC writing tool requires

  9. MEASURING THE GLOBAL OCEAN SURFACE CIRCULATION WITH SATELLITE AND IN SITU OBSERVATIONS

    E-print Network

    Dohan(1) , Fabrice Bonjean(2) , Luca Centurioni(3) , Meghan Cronin(4) , Gary Lagerloef(5) , Dong-Kyu Lee, 98115, USA: Meghan.F.Cronin@noaa.gov (5) Earth & Space Research, 2101 Fourth Ave, Suite 1310, Seattle WA-735, Korea: lee@east.ocean.pusan.ac.kr (7) Physical Oceanography Division, Atlantic Oceanographic

  10. Local strength and global weakness: A maritime network perspective on South Korea as Northeast Asia's

    E-print Network

    Boyer, Edmond

    Asia's logistics hub Published in: KMI International Journal of Maritime Affairs and Fisheries, 1, Logistics and Port Research Korea Maritime Institute Bangbae-dong Seoul Republic of Korea Tel: +82 adopted an outward-looking strategy forged on a strong alliance between the Army (General Park Chung Hee

  11. Direct evidence for a supernova interacting with a large amount of hydrogen-free circum-stellar material.

    E-print Network

    Faraon, Andrei

    -declining light curve ( 600 days) that cannot be powered by 56Ni/56Co radioactivity, the com- mon energy sourceDirect evidence for a supernova interacting with a large amount of hydrogen-free circum, Kashiwa-shi, Chiba, 277-8583, Japan. Dong Xu Dark Cosmology Centre, Niels Bohr Institute, University

  12. Dual-level parallelism for high-order CFD methods q

    E-print Network

    Dong, Suchuan "Steven"

    Dual-level parallelism for high-order CFD methods q Suchuan Dong, George Em Karniadakis * Division structures arising from deterministic and stochastic CFD problems. We take a coarse grain approach to OpenMP; Spectral element method; CFD 1. The hybrid model The hybrid programming (MPI/OpenMP or MPI

  13. Students' Difficulties in Transfer of Problem Solving Across Representations

    E-print Network

    Zollman, Dean

    Students' Difficulties in Transfer of Problem Solving Across Representations Dong-Hai Nguyen and N-2601 Abstract. Studies indicate that the use of multiple representations in teaching helps students become better problem solvers. We report on a study to investigate students' difficulties with multiple

  14. CONVERTISSEUR THERMOLECTRIQUE A SEMICONDUCTEUR SEMI-LIQUIDE

    E-print Network

    Paris-Sud XI, Université de

    61. CONVERTISSEUR THERMOÉLECTRIQUE A SEMICONDUCTEUR SEMI-LIQUIDE Par NGUYEN VAN DONG et EUGÈNE large gradient thermique. Jus- qu'à présent, les thermoéléments utilisés dans les convertisseurs [3]. Ce rapport décrit le premier convertisseur expéri- mental utilisant comme matériau de base le

  15. IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION, VOL. 60, NO. 4, APRIL 2012 1785 A Series Slot Array Antenna for 45 -Inclined Linear

    E-print Network

    Nam, Sangwook

    Antenna for 45 -Inclined Linear Polarization With SIW Technology Dong-yeon Kim, Woo-Sung Chung, Chang-wave series slot array antenna with 45 -inclined linear polarization in the Ka-band is presented. The proposedBi, and 53.7%, respectively. Furthermore, the side lobe levels (SLLs) were verified for each cutting plane

  16. CPFLOW for Power Tracer and Voltage Monitoring

    E-print Network

    contact: Professor Hsiao-Dong Chiang School of Electrical and Computer Engineering Cornell University 328 a restructuring electric power industry and educating the next generation of power engineers. More information the `nose' point without the numerical difficulties of repeated power flow solvers. It can generate P-V, Q

  17. jinxl77@gmail.com, *jsno@snu.ac.kr, **djshin@hanyang.ac.kr A Study on the Source Antenna Selection

    E-print Network

    No, Jong-Seon

    on the Source Antenna Selection for Decode-and-Forward Protocol Xianglan Jin, Jong-Seon No*, Dong-Joon Shin. Win, "MIMO systems with antenna selection," IEEE Microwave Magazine, vol. 5, no. 1, pp. 46­56, 2004. [5] Z. Chen, J. Yuan, B. Vucetic and Z. Zhou, "Performance of Alamouti scheme with transmit antenna

  18. Distributed Performance of Polymer Electrolyte Fuel Cells under Low-Humidity Conditions

    E-print Network

    Mench, Matthew M.

    Distributed Performance of Polymer Electrolyte Fuel Cells under Low-Humidity Conditions Q. Dong, Pennsylvania 16802, USA b W.L. Gore & Associates, Gore Fuel Cell Technologies, Incorporated, Elkton, Maryland 21921, USA For reduced system complexity and compactness, it is desirable to operate polymer electrolyte

  19. IOP PUBLISHING SMART MATERIALS AND STRUCTURES Smart Mater. Struct. 18 (2009) 065017 (7pp) doi:10.1088/0964-1726/18/6/065017

    E-print Network

    Lin, Liwei

    2009-01-01

    IOP PUBLISHING SMART MATERIALS AND STRUCTURES Smart Mater. Struct. 18 (2009) 065017 (7pp) doi:10-consuming and low throughput assembly steps, direct growth of nanostructures on top of a glass capillary using, Sinchon-dong, Seodaemun-Gu, Seoul 120-749, Korea. glass capillary with two terminal electrodes [7

  20. The 4th KISTEC International Seminar on Safety of Infrastructures, Gyeongbuk, Korea, July 22, 2005 Monitoring and Management of Water Supply Systems

    E-print Network

    Shinozuka, Masanobu

    Monitoring and Management of Water Supply Systems Masanobu Shinozuka1 Xuejiang Dong2 Department of Civil at University of California, Irvine for monitoring and management of water supply networks. As such/malfunction in a water delivery system taking advantage of sharply transient change in hydraulic parameters such as water

  1. Fundamental Study of Single Biomass Particle Combustion

    E-print Network

    Berning, Torsten

    reasonably close to the conditions in a power plant boiler, i.e., reasonably high temperatures (up to 1600°C of Denmark, and at Avedøre Power Plant, DONG Energy, I am grateful for the chance to visit and be a partFundamental Study of Single Biomass Particle Combustion Maryam Momeni #12;Fundamental Study

  2. 1564 IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS, VOL. 9, NO. 5, MAY 2010 Perturbation Analysis for Spectrum Sharing in Cognitive Radio Networks

    E-print Network

    Kim, Dong In

    for Spectrum Sharing in Cognitive Radio Networks Hengameh Keshavarz, Ekram Hossain, Sima Noghanian, and Dong radio, power allocation, perturbation analysis. I. INTRODUCTION COGNITIVE radio is a promising. This fact inspired researchers to propose the notion of cognitive radio or using these temporary unused

  3. Eect of gap ow on shuttle heat transfer Ho-Myung Chang a,*, Dae-Jong Park a

    E-print Network

    Chang, Ho-Myung

    a Department of Mechanical Engineering, Hong Ik University, 72-1 Sangsu-Dong, Mapo-Ku, Seoul 121-791, South Korea b Korea Advanced Institute of Science and Technology, Taejon 305-701, South Korea Received 31 is a key component in many cryogenic refrigerators such as Stirling, Giord± McMahon, Vuilleumier and Claude

  4. 4072 VOLUME 13J O U R N A L O F C L I M A T E 2000 American Meteorological Society

    E-print Network

    profiles derived from the first spaceborne precipitation radar (PR), which is on board the Tropical of Reflectivity Profiles from the First Year of TRMM Radar Data DONG-BIN SHIN, GERALD R. NORTH, AND KENNETH P drastically (Shin and North 2000). The other significant goal of TRMM is to provide three-dimensional radar

  5. Pattern diversity with multi-mode circular patch antennas in clustered MIMO channels

    Microsoft Academic Search

    Antonio Forenza; Frank Sun; Robert W. Heath Jr

    2005-01-01

    The throughput that a MIMO channel can support is a function of different array parameters. Another technique, for miniaturized antenna designs, is polarization\\/pattern diversity where the antennas are designed to radiate with orthogonal radiation patterns and polarizations as a means to create uncorrelated channels across different array elements. The benefits of pattern diversity have been shown by L. Dong et

  6. Knowledge Vault: A Web-Scale Approach to Probabilistic Knowledge Fusion

    E-print Network

    Murphy, Kevin Patrick

    Knowledge Vault: A Web-Scale Approach to Probabilistic Knowledge Fusion Xin Luna Dong , Evgeniy primarily focused on text-based extraction, which can be very noisy. Here we introduce Knowledge Vault information sources. The Knowledge Vault is substantially bigger than any previously published structured

  7. Session: Poster Session + Poster Award + Scientific Award + Excellent young wind doctor award (PO.65) Track: Technical

    E-print Network

    FOR OFFSHORE WIND POWER (abstract-ID: 252) Pierre Pinson (DTU-Informatics and Mathematical Modelling, , Denmark, Denmark (6) Jesper Runge Kristoffersen, Denmark (7) (1) WEPROG (2) DTU-Informatics and Mathematical (5) Risø DTU (6) DONG Energy Generation (7) Vattenfall One of the benefits of Offshore Wind Power

  8. Leukemia Research 30 (2006) 10191025 Aven overexpression: Association with poor prognosis

    E-print Network

    Abraham, Nader G.

    2006-01-01

    Leukemia Research 30 (2006) 1019­1025 Aven overexpression: Association with poor prognosis in childhood acute lymphoblastic leukemia Jaewon Choia, Yu Kyeong Hwangb, Ki Woong Sunga,, Dong Hyun Kima, Keon-apoptotic protein. In this study, Aven expression in 91 children with acute lym- phoblastic leukemia (ALL

  9. Nanomaterials-Enabled Dye-Sensitized Solar Cells and Jun Lou1

    E-print Network

    O-7 Nanomaterials-Enabled Dye-Sensitized Solar Cells Pei Dong1 and Jun Lou1 1 sensitized solar cells (DSCs), the third generation of solar cells, have attracted more and more attention Department of Mechanical Engineering and Materials Science, Rice University, Houston, Texas, U.S.A. Dye

  10. Gene expression profile of cytokine and growth factor during differentiation of bone marrow-derived mesenchymal stem cell

    E-print Network

    Abraham, Nader G.

    #12;of localization, self-renewal and differentiation of hema- topoietic stem cells [1,2]. Mesenchymal-derived mesenchymal stem cell Dong Hyun Kim a,b , Keon Hee Yoo b , Kyung Suk Choi b , Jaewon Choi b , Sang-Yun Choi Mesenchymal stem cells (MSCs), which are adherent stromal cells of a nonhematopoietic origin, have the ability

  11. G SOUTHWEST FOREST SERVICE Forest andRU. S.DEPARTMENT OF AGRICULTURE

    E-print Network

    Standiford, Richard B.

    , CALIFORNIA 94701 Experime Response of Fucalyptus Species t o Frost Damage a t the Redwood Experimental Forest to frost damage at the Redwood Experimental Forest. Res. Note PSW-331, 5 p., Pacific Southwest Forest to determine if certain Eucalyptus species could be grown dong the California North Coast for timber

  12. Competition on Counter Measures to 2-D Facial Spoofing Attacks Murali Mohan Chakka1

    E-print Network

    Anjos, André

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    identify the vehicle. As a first step, we design ForeSight, a system that dynamically integrates, it is im- portant to know the electronic identities (EID, e.g., the IP addresses) of the target vehicleForeSight: Mapping Vehicles in Visual Domain and Electronic Domain Dong Li, Zhixue Lu, Tarun Bansal

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    of this disease and consider- able normal tissue toxicity in patients. Most pancreatic cancer patients of Action of b-Lapachone for Pancreatic Cancer Therapy Long Shan Li1,2 , Erik A. Bey1,2 , Ying Dong1 for the treatment of pancreatic cancers, the lack of knowledge of the compound's mechanism of action prevented

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    Sherwood, Steven

    /Microwave Limb Sounder (UARS/MLS) 203-GHz radiance measurements at tangent pressures between 200 and 46 h clear-sky cases. Unlike infrared/visible cloud observa- tions, the 203-GHz radiances can penetrate most, California Institute of Technology, MS 183-701, 4800 Oak Grove Drive, Pasadena, CA 91109. E-mail: Dong

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    Dong, Min

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    Cheng, Jianjun

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    Iyama, Osamu

    of the rings of differential operators on central 2-arrangements 12:50­13:30 21 Hom-orthogonal partial tilting On modules of finite complexity over selfinjective algebras I 9:40­10:30 Dong Yang On derived simple algebras¨o The representation rings of the dihedral 2-groups 13:50­14:30 21 APR tilting modules and quiver mutations 24

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    and Weinberg, 2000). In recent years, the Hippo signaling pathway has emerged as an evolutionarily conserved a framework of the structure of this pathway. Activation of the Serine/Threonine kinase Hippo (Hpo) leads to the suppression of the transcriptional co-activator Yorkie (Yki) (Dong et al., 2007; Huang et al., 2005

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    for a hybrid direct-sequence frequency-hopping spread-spectrum signal. The work presented in this paper looks/FH spread-spectrum signal in an ISM band Hanyu Li, Mubashir Syed and Yu-Dong Yao*, Department of Electrical reuse. Technologies like smart antennas [2­4], spread-spectrum modulation, software-defined radio

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    .1049/iet-com.2009.0130 ISSN 1751-8628 Fair scheduling with rate control for IEEE 802.16 broadband wireless networks J.-H. Jeon J.-T. Lim Department of Electrical Engineering and Computer Science, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong Yuseong-gu Daejeon 305-701, Korea E-mail: jtlim

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    analysis of the environmental performance of photovoltaics: the devil is in the details Jan 22 Xioabin Dong, Soil & Nutrient Management, Soil and Water Science, UF Rainfed agricultural watersheds and management 16 Shannon Duffy MS student, Soil and Water Science, UF Litter decomposition's role in nutrient

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    ­Rayleigh scattering in a distributed fiber Raman amplifier Kap-Dong Park Condensed Matter Research Institute, School 1 and WDM 2), not only to generate sixth-order Raman Stokes lines at 1471 nm but also to amplify two nonlinear processes from the distributed Raman gain and the reduced Brillouin threshold from the seeding

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    Maine, University of

    A model study of the circulation in the Pearl River Estuary (PRE) and its adjacent coastal waters results with the in situ measurements collected during the Pearl River Estuary Pollution Project (PREPP. Xue, L. X. Dong, W. B. Guan, and J. L. Su, A model study of the circulation in the Pearl River Estuary

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    Paris-Sud XI, Université de

    ). However, due to the continued dependence of world trade on sea transport ­ more than 90% world trade port city, entropy 1 Korea Maritime Institute (KMI), KBS Media Center, Mapo Gu, Sangam Dong 1652 Seoul seaports and port cities worldwide. Recurrent trends such as industrial shifts within the world system

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    of Medicine, University of Illinois at Chicago, 1601 W. Taylor St., Chicago, IL 60612, United States Abstract (-) and the methylation switch (+/-) in schizophrenia Dennis R. Grayson , Ying Chen, Erminio Costa, Erbo Dong, AlessandroRNAs represents 2 of the more consistent findings thus far described in post-mortem material from schizophrenia

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    42nd AIAA Fluid Dynamics Conference and Exhibit AIAA 2012 25 June ­ 28 June 2012, New Orleans Aspect-Ratio Plate in Translation and Rotation Hui Wan1 , Haibo Dong2 , Chengyu Li3 , and Zongxian Liang3 Department of Mechanical & Materials Engineering Wright State University, Dayton, OH 45435 A low aspect

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    E-print Network

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    Analysis of Noise Isolation Methods on Split Power/Ground Plane of Multi-layered Package and PCBScience, Korea Advanced Institute of Scienceand Technology, 373-1 Guseong-dong,Yuseong-gu, Daejon 305-701, Korea://tera.kaist.ac.kr ABSTRACT - Various noise isolation methods for low jitter on powerlground plane are thoroughly analyzed

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    of the Naval Architecture and Ocean Engineering, Seoul National University, Shilim-Dong, Kwanak-gu, Seoul 151-gu, Seoul 151-742, Korea e-mail: jhcha79@snu.ac.kr K.-Y. Lee Á T. Kim Department of the Naval Architecture

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    Adams, J.; Adler, C.; Aggarwal, MM; Ahammed, Z.; Amonett, J.; Anderson, BD; Anderson, M.; Arkhipkin, D.; Averichev, GS; Badyal, SK; Balewski, J.; Barannikova, O.; Barnby, LS; Baudot, J.; Bekele, S.; Belaga, VV; Bellwied, R.; Berger, J.; Bezverkhny, BI; Bhardwaj, S.; Bhaskar, P.; Bhati, AK; Bichsel, H.; Billmeier, A.; Bland, LC; Blyth, CO; Bonner, BE; Botje, M.; Boucham, A.; Brandin, A.; Bravar, A.; Cadman, RV; Cai, XZ; Caines, H.; Sanchez, MCD; Cardenas, A.; Carroll, J.; Castillo, J.; Castro, M.; Cebra, D.; Chaloupka, P.; Chattopadhyay, S.; Chen, HF; Chen, Y.; Chernenko, SP; Cherney, M.; Chikanian, A.; Choi, B.; Christie, W.; Coffin, JP; Cormier, TM; Cramer, JG; Crawford, HJ; Das, D.; Das, S.; Derevschikov, AA; Didenko, L.; Dietel, T.; Dong, X.; Draper, JE; Du, F.; Dubey, AK; Dunin, VB; Dunlop, JC; Mazumdar, MRD; Eckardt, V.; Efimov, LG; Emelianov, V.; Engelage, J.; Eppley, G.; Erazmus, B.; Fachini, P.; Faine, V.; Faivre, J.; Fatemi, R.; Filimonov, K.; Filip, P.; Finch, E.; Fisyak, Y.; Flierl, D.; Foley, KJ; Fu, J.; Gagliardi, Carl A.; Ganti, MS; Gutierrez, TD; Gagunashvili, N.; Gans, J.; Gaudichet, L.; Germain, M.; Geurts, F.; Ghazikhanian, V.; Ghosh, P.; Gonzalez, JE; Grachov, O.; Grigoriev, V.; Grosnick, D.; Guedon, M.; Guertin, SM; Gupta, A.; Gushin, E.; Hallman, TJ; Hardtke, D.; Harris, JW; Heinz, M.; Henry, TW; Heppelmann, S.; Herston, T.; Hippolyte, B.; Hirsch, A.; Hjort, E.; Hoffmann, GW; Horsley, M.; Huang, HZ; Huang, SL; Humanic, TJ; Igo, G.; Ishihara, A.; Jacobs, P.; Jacobs, WW; Janik, M.; Johnson, I.; Jones, PG; Judd, EG; Kabana, S.; Kaneta, M.; Kaplan, M.; Keane, D.; Kiryluk, J.; Kisiel, A.; Klay, J.; Klein, SR; Klyachko, A.; Koetke, DD; Kollegger, T.; Konstantinov, AS; Kopytine, M.; Kotchenda, L.; Kovalenko, AD; Kramer, M.; Kravtsov, P.; Krueger, K.; Kuhn, C.; Kulikov, AI; Kumar, A.; Kunde, GJ; Kunz, CL; Kutuev, RK; Kuznetsov, AA; Lamont, MAC; Landgraf, JM; Lange, S.; Lansdell, CP; Lasiuk, B.; Laue, F.; Lauret, J.; Lebedev, A.; Lednicky, R.; Leontiev, VM; LeVine, MJ; Li, C.; Li, Q.; Lindenbaum, SJ; Lisa, MA; Liu, F.; Liu, L.; Liu, Z.; Liu, QJ; Ljubicic, T.; Llope, WJ; Long, H.; Longacre, RS; Lopez-Noriega, M.; Love, WA; Ludlam, T.; Lynn, D.; Ma, J.; Ma, YG; Magestro, D.; Mahajan, S.; Mangotra, LK; Mahapatra, AP; Majka, R.; Manweiler, R.; Margetis, S.; Markert, C.; Martin, L.; Marx, J.; Matis, HS; Matulenko, YA; McShane, TS; Meissner, F.; Melnick, Y.; Meschanin, A.; Messer, M.; Miller, ML; Milosevich, Z.; Minaev, NG; Mironov, C.; Mishra, D.; Mitchell, J.; Mohanty, B.; Molnar, L.; Moore, CF; Mora-Corral, MJ; Morozov, V.; de Moura, MM; Munhoz, MG; Nandi, BK; Nayak, SK; Nayak, TK; Nelson, JM; Nevski, P.; Nikitin, VA; Nogach, LV; Norman, B.; Nurushev, SB; Odyniec, G.; Ogawa, A.; Okorokov, V.; Oldenburg, M.; Olson, D.; Paic, G.; Pandey, SU; Pal, S.; Panebratsev, Y.; Panitkin, SY; Pavlinov, AI; Pawlak, T.; Perevoztchikov, V.; Peryt, W.; Petrov, VA; Phatak, SC; Picha, R.; Pluta, J.; Porile, N.; Porter, J.; Poskanzer, AM; Potekhin, M.; Potrebenikova, E.; Potukuchi, BVKS; Prindle, D.; Pruneau, C.; Putschke, J.; Rai, G.; Rakness, G.; Raniwala, R.; Raniwala, S.; Ravel, O.; Ray, RL; Razin, SV; Reichhold, D.; Reid, JG; Renault, G.; Retiere, F.; Ridiger, A.; Ritter, HG; Roberts, JB; Rogachevski, OV; Romero, JL; Rose, A.; Roy, C.; Ruan, LJ; Rykov, V.; Sahoo, R.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Savin, I.; Schambach, J.; Scharenberg, RP; Schmitz, N.; Schroeder, LS; Schweda, K.; Seger, J.; Seliverstov, D.; Seyboth, P.; Shahaliev, E.; Shao, M.; Sharma, M.; Shestermanov, KE; Shimanskii, SS; Singaraju, RN; Simon, F.; Skoro, G.; Smirnov, N.; Snellings, R.; Sood, G.; Sorensen, P.; Sowinski, J.; Spinka, H. M.; Srivastava, B.; Stanislaus, S.; Stephenson, EJ; Stock, R.; Stolpovsky, A.; Strikhanov, M.; Stringfellow, B.; Struck, C.; Suaide, AAP; Sugarbaker, E.; Suire, C.; Sumbera, M.; Surrow, B.; Symons, TJM; de Toledo, AS; Szarwas, P.; Tai, A.; Takahashi, J.; Tang, AH; Sorensen, P.; Thein, D.; Thomas, JH; Tikhomirov, V.; Tokarev, M.; Tonjes, MB; Trainor, TA; Trentalange, S.; Tribble, Robert E.; Trivedi, MD; Trofimov, V.; Tsai, O.; Ullrich, T.; Underwood, DG; Van Buren, G.; Vander Molen, AM; Vasiliev, AN; Vasiliev, M.; Vigdor, SE; Viyogi, YP; Voloshin, SA; Wang, F.; Wang, G.; Wang, XL; Wang, ZM; Ward, H.; Watson, JW; Wells, R.; Westfall, GD; Whitten, C.; Wieman, H.; Willson, R.; Wissink, SW; Witt, R.; Wood, J.; Wu, J.; Xu, N.; Xu, Z.; Xu, ZZ; Yakutin, AE; Yamamoto, E.; Yang, J.; Yepes, P.; Yurevich, VI; Zanevski, YV; Zborovsky, I.; Zhang, H.; Zhang, HY; Zhang, WM; Zhang, ZP; Zolnierczuk, PA; Zoulkarneev, R.; Zoulkarneeva, J.; Zubarev, AN; STAR Collaboration.

    2004-01-01

    . Chattopadhyay,34 H. F. Chen,28 Y. Chen,6 S. P. Chernenko,10 M. Cherney,8 A. Chikanian,39 B. Choi,32 W. Christie,2 J. P. Coffin,14 T. M. Cormier,37 J. G. Cramer,36 H. J. Crawford,4 D. Das,34 S. Das,34 A. A. Derevschikov,24 L. Didenko,2 T. Dietel,12 X. Dong,28...

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    E-print Network

    Xing, Eric P.

    53 Alteration in Human Esophageal Cancer1 Eric Poe Xing,2 Guang-Yu Yang,2 Li-Dong Wang, Stephanie Tao- nohistochemical and genetic analyses, we found that alter- ation of Rb and p53 had an even stronger association, Zhengzhou, 457500 China [L-D. W.] ABSTRACT To understand the alterations of Rb tumor suppressor gene

  2. 2013NatureAmerica,Inc.Allrightsreserved. Arabidopsis mesophyll protoplasts: a versatile cell

    E-print Network

    Sheen, Jen

    system for transient gene expression analysis Sang-Dong Yoo1,2, Young-Hee Cho1,2 & Jen Sheen1,2 1:10.1038/nprot.2007.199 The transient gene expression system using Arabidopsis mesophyll protoplasts for a system of transient expression in Arabidopsis mesophyll protoplast (TEAMP) and provide troubleshooting

  3. JOURNAL OF GEOPHYSICAL RESEARCH, VOL. ???, XXXX, DOI:10.1029/, Forecast evaluation of the CME geoeffectiveness

    E-print Network

    and Space Science, Chungnam National Univer- sity, 220 Gung-dong, Yuseong-gu, Daejeon, 305-754, Korea (rskim@cnu.ac.kr) Su-Chan Bong, K.-S. Cho, Y.-H. Kim, Y.-J. Moon, Y.-D. Park, Korea Astronomy and Space Science Science, Chungnam National University, Daejeon, Korea 2 Korea Astronomy and Space Science Institute

  4. SAG101 Forms a Ternary Complex with EDS1 and PAD4 and Is Required for Resistance Signaling against Turnip

    E-print Network

    Kachroo, Pradeep

    Turnip Crinkle Virus Shifeng Zhu1. , Rae-Dong Jeong1.¤a , Srivathsa C. Venugopal1¤b , Ludmila Lapchyk1 against turnip crinkle virus (TCV) as well as avrRps4 expressing Pseudomonas syringae. Interestingly Turnip Crinkle Virus. PLoS Pathog 7(11): e1002318. doi:10.1371/journal.ppat.1002318 Editor: Shou-Wei Ding

  5. Earthworm avoidance of biochar can be mitigated by wetting , William C. Hockaday b

    E-print Network

    Alvarez, Pedro J.

    Earthworm avoidance of biochar can be mitigated by wetting Dong Li a , William C. Hockaday b Keywords: Eisenia foetida Avoidance test Biochar Desiccation MDA SOD PAH a b s t r a c t Biochar has and mitigate any unintended consequences associated with soil biochar amendment. We conducted soil avoidance

  6. This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research

    E-print Network

    This article appeared in a journal published by Elsevier. The attached copy is furnished's personal copy High-temperature tensile behavior of freestanding Au thin films Gi-Dong Sim and Joost J. Vlassak School of Engineering and Applied Science, Harvard University, Cambridge, MA 02138, USA Received 8

  7. DEPARTMENT OF STATISTICS University of Wisconsin

    E-print Network

    Liblit, Ben

    DEPARTMENT OF STATISTICS University of Wisconsin 1210 West Dayton St. Madison, WI 53706 TECHNICAL of Statistics, University of Wisconsin, Madison WI Dong Xiang SAS Institute, Cary NC Fangyu Gao Department of Statistics, University of Wisconsin, Madison WI Ronald Klein, MD Barbara Klein, MD Department

  8. 2008 31 2 e-mail : lucidream@ccl.snu.ac.kr, jsno@snu.ac.kr, djshin@hanyang.ac.kr

    E-print Network

    No, Jong-Seon

    @ccl.snu.ac.kr, jsno@snu.ac.kr, djshin@hanyang.ac.kr Bit Inverted SLM Scheme for PAPR Reduction in OFDM Signals *Hyun-Bae Jeon, Jong-Seon No, Dong-Joon Shin Department of Electrical Engineering and Computer Science, Seoul to average power ratio (PAPR) of orthogonal frequency division multiplexing (OFDM) signals modulated with QAM

  9. A New Selected Mapping Scheme for PAPR Reduction in OFDM Systems

    E-print Network

    No, Jong-Seon

    A New Selected Mapping Scheme for PAPR Reduction in OFDM Systems Kee-Hoon Kim, Hyun-Bae Jeon, and Jong-Seon No Department of Electrical Engineering and Computer Science, INMC Seoul National University@ccl.snu.ac.kr, jsno@snu.ac.kr Dong-Joon Shin Department of Electronic Engineering Hanyang University, Seoul, 133

  10. APPLICATION OF THE MULTILEVEL UV METHOD TO CALCULATE MICROWAVE

    E-print Network

    Tsang, Leung

    structure of the shapes of air bubbles based on Lord Kelvin's tetrakaidecahedron struc- ture that has close FOAM WITH KELVIN'S TETRAKAIDECAHEDRON STRUCTURE Peng Xu,1 Leung Tsang,1,2 and Dong Chen1 1 Department- istic foam structure. The Kelvin-cell-shaped foam, with Tetrakaid- ecahedron structure, has close

  11. Designing a Touch-Screen SenseCam Browser to Support an Aging

    E-print Network

    Lee, Hyowon

    , is a small wearable camera which passively and automatically captures thousands of images per day to be presented to the user [2]. An event could be eating breakfast, dong the crossword or walking outside. The benefits of SenseCam as a memory retrieval aid are emerging at a rapid pace and the interest in Sense

  12. TGF-b-activated Smad3 represses MEF2-dependent transcription in

    E-print Network

    Derynck, Rik

    TGF-b-activated Smad3 represses MEF2-dependent transcription in myogenic differentiation Dong Liu-b signaling effector Smad3 mediates this inhibition, by interfering with the assembly of myogenic b now show that TGF-b-activated Smad3 sup- presses the function of MEF2, a second class of essential

  13. Cellular/Molecular Sequential Postsynaptic Maturation Governs the Temporal

    E-print Network

    Luscher, Bernhard

    and Glutamatergic Synaptogenesis in Rat Embryonic Cultures Lunbin Deng,1,2* Jun Yao,1,2* Cheng Fang,1,2,3 Ning Dong and glutamatergic synaptogenesis in embryonichypothalamiccultures,whichcontain 40%GABAergicand 60GABAA receptorsbutaverylowlevelofglutamatereceptors.Withinthe first week of culture, the time course of GABAergic synaptogenesis in embryonic neurons

  14. Assimilation of T-TREC-Retrieved Winds from Single-Doppler Radar with an Ensemble Kalman Filter for the Forecast of Typhoon Jangmi (2008)

    E-print Network

    Xue, Ming

    2008-01-01

    for the Forecast of Typhoon Jangmi (2008) Mingjun Wang1,2 , Ming Xue1,2,3 , Kun Zhao1 and Jili Dong2 1 Key using an ensemble Kalman filter, over a 2-hour window shortly after Typhoon Jangmi (2008) entered the Vr of the typhoon structure and intensity that more closely match observations than analyses produced using Vr data

  15. Energy Transfer Dynamics in ReI-Based Polynuclear Assemblies: A Quantitative Application of Forster Theory

    E-print Network

    McCusker, James K.

    ¨rster Theory Troy E. Knight, Dong Guo, Juan Pablo Claude, and James K. McCusker* Department of Chemistry, and photophysical properties of a new family of tetranuclear FeRe3 chromophore-quencher complexes having the general systems: this fact coupled with the absence of optical signatures for the expected charge

  16. Australian Institute of Aboriginal Studies Catalogue of Tape Archive No. 6.

    ERIC Educational Resources Information Center

    Australian Inst. of Aboriginal Studies, Canberra.

    The aboriginal studies listed in this catalogue are indexed according to language/tribe and subject (linguistic studies, myths and stories, songs and dances, dongs and music, and speech). Entries are listed alphabetically under the depositor's name. Language/tribe headings are from the Institute's Preliminary Tribal Index. Summaries are brief but…

  17. 77 FR 2758 - Certain Portable Communication Devices; Institution of Investigation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ...For the purpose of the investigation so instituted, the following...upon which this notice of investigation shall be served: (a) The...Electronics, Inc., LG Twin Towers, 20, Yoido-dong...The Office of Unfair Import Investigations, U.S. International...

  18. 76 FR 13432 - In the Matter of Certain Display Devices, Including Digital Televisions and Monitors II; Notice...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ...For the purpose of the investigation so instituted, the following...upon which this notice of investigation shall be served: (a) The...Electronics, Inc., LG Twin Towers, 20 Yeouido-dong...The Office of Unfair Import Investigations, U.S. International...

  19. 76 FR 40746 - In the Matter of Certain Light-Emitting Diodes and Products Containing Same; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ...For the purpose of the investigation so instituted, the following...upon which this notice of investigation shall be served: (a) The...Electronics, Inc., LG Twin Towers, 20, Yeouido-dong...CA 92131. (3) For the investigation so instituted, the...

  20. 78 FR 64009 - Certain Optical Disc Drives, Components Thereof, and Products Containing the Same; Institution of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ...For the purpose of the investigation so instituted, the following...upon which this notice of investigation shall be served: (a) The...Electronics, Inc., LG Twin Towers 20, Yoido-dong...CA 95134. (3) For the investigation so instituted, the...