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Sample records for double auction mechanism

  1. A Greedy Double Auction Mechanism for Grid Resource Allocation

    NASA Astrophysics Data System (ADS)

    Ding, Ding; Luo, Siwei; Gao, Zhan

    To improve the resource utilization and satisfy more users, a Greedy Double Auction Mechanism(GDAM) is proposed to allocate resources in grid environments. GDAM trades resources at discriminatory price instead of uniform price, reflecting the variance in requirements for profits and quantities. Moreover, GDAM applies different auction rules to different cases, over-demand, over-supply and equilibrium of demand and supply. As a new mechanism for grid resource allocation, GDAM is proved to be strategy-proof, economically efficient, weakly budget-balanced and individual rational. Simulation results also confirm that GDAM outperforms the traditional one on both the total trade amount and the user satisfaction percentage, specially as more users are involved in the auction market.

  2. Statistical theory of the continuous double auction

    NASA Astrophysics Data System (ADS)

    Smith, Eric; Doyne Farmer, J.; Gillemot, László; Krishnamurthy, Supriya

    2003-12-01

    Most modern financial markets use a continuous double auction mechanism to store and match orders and facilitate trading. In this paper we develop a microscopic dynamical statistical model for the continuous double auction under the assumption of IID random order flow, and analyse it using simulation, dimensional analysis, and theoretical tools based on mean field approximations. The model makes testable predictions for basic properties of markets, such as price volatility, the depth of stored supply and demand versus price, the bid-ask spread, the price impact function, and the time and probability of filling orders. These predictions are based on properties of order flow and the limit order book, such as share volume of market and limit orders, cancellations, typical order size, and tick size. Because these quantities can all be measured directly there are no free parameters. We show that the order size, which can be cast as a non-dimensional granularity parameter, is in most cases a more significant determinant of market behaviour than tick size. We also provide an explanation for the observed highly concave nature of the price impact function. On a broader level, this work suggests how stochastic models based on zero intelligence agents may be useful to probe the structure of market institutions. Like the model of perfect rationality, a stochastic zero intelligence model can be used to make strong predictions based on a compact set of assumptions, even if these assumptions are not fully believable.

  3. Poisson-process generalization for the trading waiting-time distribution in a double-auction mechanism

    NASA Astrophysics Data System (ADS)

    Cincotti, Silvano; Ponta, Linda; Raberto, Marco; Scalas, Enrico

    2005-05-01

    In this paper, empirical analyses and computational experiments are presented on high-frequency data for a double-auction (book) market. Main objective of the paper is to generalize the order waiting time process in order to properly model such empirical evidences. The empirical study is performed on the best bid and best ask data of 7 U.S. financial markets, for 30-stock time series. In particular, statistical properties of trading waiting times have been analyzed and quality of fits is evaluated by suitable statistical tests, i.e., comparing empirical distributions with theoretical models. Starting from the statistical studies on real data, attention has been focused on the reproducibility of such results in an artificial market. The computational experiments have been performed within the Genoa Artificial Stock Market. In the market model, heterogeneous agents trade one risky asset in exchange for cash. Agents have zero intelligence and issue random limit or market orders depending on their budget constraints. The price is cleared by means of a limit order book. The order generation is modelled with a renewal process. Based on empirical trading estimation, the distribution of waiting times between two consecutive orders is modelled by a mixture of exponential processes. Results show that the empirical waiting-time distribution can be considered as a generalization of a Poisson process. Moreover, the renewal process can approximate real data and implementation on the artificial stocks market can reproduce the trading activity in a realistic way.

  4. Understanding Financial Market States Using an Artificial Double Auction Market

    PubMed Central

    2016-01-01

    The ultimate value of theories describing the fundamental mechanisms behind asset prices in financial systems is reflected in the capacity of such theories to understand these systems. Although the models that explain the various states of financial markets offer substantial evidence from the fields of finance, mathematics, and even physics, previous theories that attempt to address the complexities of financial markets in full have been inadequate. We propose an artificial double auction market as an agent-based model to study the origin of complex states in financial markets by characterizing important parameters with an investment strategy that can cover the dynamics of the financial market. The investment strategies of chartist traders in response to new market information should reduce market stability based on the price fluctuations of risky assets. However, fundamentalist traders strategically submit orders based on fundamental value and, thereby stabilize the market. We construct a continuous double auction market and find that the market is controlled by the proportion of chartists, Pc. We show that mimicking the real state of financial markets, which emerges in real financial systems, is given within the range Pc = 0.40 to Pc = 0.85; however, we show that mimicking the efficient market hypothesis state can be generated with values less than Pc = 0.40. In particular, we observe that mimicking a market collapse state is created with values greater than Pc = 0.85, at which point a liquidity shortage occurs, and the phase transition behavior is described at Pc = 0.85. PMID:27031110

  5. Understanding Financial Market States Using an Artificial Double Auction Market.

    PubMed

    Yim, Kyubin; Oh, Gabjin; Kim, Seunghwan

    2016-01-01

    The ultimate value of theories describing the fundamental mechanisms behind asset prices in financial systems is reflected in the capacity of such theories to understand these systems. Although the models that explain the various states of financial markets offer substantial evidence from the fields of finance, mathematics, and even physics, previous theories that attempt to address the complexities of financial markets in full have been inadequate. We propose an artificial double auction market as an agent-based model to study the origin of complex states in financial markets by characterizing important parameters with an investment strategy that can cover the dynamics of the financial market. The investment strategies of chartist traders in response to new market information should reduce market stability based on the price fluctuations of risky assets. However, fundamentalist traders strategically submit orders based on fundamental value and, thereby stabilize the market. We construct a continuous double auction market and find that the market is controlled by the proportion of chartists, Pc. We show that mimicking the real state of financial markets, which emerges in real financial systems, is given within the range Pc = 0.40 to Pc = 0.85; however, we show that mimicking the efficient market hypothesis state can be generated with values less than Pc = 0.40. In particular, we observe that mimicking a market collapse state is created with values greater than Pc = 0.85, at which point a liquidity shortage occurs, and the phase transition behavior is described at Pc = 0.85. PMID:27031110

  6. A QoS-Enabled Double Auction Protocol for the Service Grid

    NASA Astrophysics Data System (ADS)

    Gao, Zhan; Luo, Siwei

    Traditional double auction protocols only concern the price information of participants without considering their QoS requirements, which makes them unsuitable for the service grid. In this paper we first introduce QoS information into double auction to present the QoS-enabled Double Auction Protocol (QDAP). QDAP tries to assign the asks which have the least candidate bids firstly to make more participants trade and provides QoS guarantee at the same time. Simulation experiments have been performed to compare QDAP with two traditional double auction protocols and the result shows that QDAP is more suitable for the service grid.

  7. Statistical mechanics of budget-constrained auctions

    NASA Astrophysics Data System (ADS)

    Altarelli, F.; Braunstein, A.; Realpe-Gomez, J.; Zecchina, R.

    2009-07-01

    Finding the optimal assignment in budget-constrained auctions is a combinatorial optimization problem with many important applications, a notable example being in the sale of advertisement space by search engines (in this context the problem is often referred to as the off-line AdWords problem). On the basis of the cavity method of statistical mechanics, we introduce a message-passing algorithm that is capable of solving efficiently random instances of the problem extracted from a natural distribution, and we derive from its properties the phase diagram of the problem. As the control parameter (average value of the budgets) is varied, we find two phase transitions delimiting a region in which long-range correlations arise.

  8. Auction Mechanism to Allocate Air Traffic Control Slots

    NASA Technical Reports Server (NTRS)

    Raffarin, Marianne

    2003-01-01

    This article deals with an auction mechanism for airspace slots, as a means of solving the European airspace congestion problem. A disequilibrium, between Air Traffic Control (ATC) services supply and ATC services demand are at the origin of almost one fourth of delays in the air transport industry in Europe. In order to tackle this congestion problem, we suggest modifying both pricing and allocation of ATC services, by setting up an auction mechanism. Objects of the auction will be the right for airlines to cross a part of the airspace, and then to benefit from ATC services over a period corresponding to the necessary time for the crossing. Allocation and payment rules have to be defined according to the objectives of this auction. The auctioneer is the public authority in charge of ATC services, whose aim is to obtain an efficient allocation. Therefore, the social value will be maximized. Another objective is to internalize congestion costs. To that end, we apply the principle of Clarke-Groves mechanism auction: each winner has to pay the externalities imposed on other bidders. The complex context of ATC leads to a specific design for this auction.

  9. Adaptive Sniping for Volatile and Stable Continuous Double Auction Markets

    NASA Astrophysics Data System (ADS)

    Toft, I. E.; Bagnall, A. J.

    This paper introduces a new adaptive sniping agent for the Continuous Double Auction. We begin by analysing the performance of the well known Kaplan sniper in two extremes of market conditions. We generate volatile and stable market conditions using the well known Zero Intelligence-Constrained agent and a new zero-intelligence agent Small Increment (SI). ZI-C agents submit random but profitable bids/offers and cause high volatility in prices and individual trader performance. Our new zero-intelligence agent, SI, makes small random adjustments to the outstanding bid/offer and hence is more cautious than ZI-C. We present results for SI in self-play and then analyse Kaplan in volatile and stable markets. We demonstrate that the non-adaptive Kaplan sniper can be configured to suit either market conditions, but no single configuration is performs well across both market types. We believe that in a dynamic auction environment where current or future market conditions cannot be predicted a viable sniping strategy should adapt its behaviour to suit prevailing market conditions. To this end, we propose the Adaptive Sniper (AS) agent for the CDA. AS traders classify sniping opportunities using a statistical model of market activity and adjust their classification thresholds using a Widrow-Hoff adapted search. Our AS agent requires little configuration, and outperforms the original Kaplan sniper in volatile and stable markets, and in a mixed trader type scenario that includes adaptive strategies from the literature.

  10. Analysis of Residential Demand Response and Double-Auction Markets

    SciTech Connect

    Fuller, Jason C.; Schneider, Kevin P.; Chassin, David P.

    2011-10-10

    Demand response and dynamic pricing programs are expected to play increasing roles in the modern Smart Grid environment. While direct load control of end-use loads has existed for decades, price driven response programs are only beginning to be explored at the distribution level. These programs utilize a price signal as a means to control demand. Active markets allow customers to respond to fluctuations in wholesale electrical costs, but may not allow the utility to control demand. Transactive markets, utilizing distributed controllers and a centralized auction can be used to create an interactive system which can limit demand at key times on a distribution system, decreasing congestion. With the current proliferation of computing and communication resources, the ability now exists to create transactive demand response programs at the residential level. With the combination of automated bidding and response strategies coupled with education programs and customer response, emerging demand response programs have the ability to reduce utility demand and congestion in a more controlled manner. This paper will explore the effects of a residential double-auction market, utilizing transactive controllers, on the operation of an electric power distribution system.

  11. Modeling and simulation of a double auction artificial financial market

    NASA Astrophysics Data System (ADS)

    Raberto, Marco; Cincotti, Silvano

    2005-09-01

    We present a double-auction artificial financial market populated by heterogeneous agents who trade one risky asset in exchange for cash. Agents issue random orders subject to budget constraints. The limit prices of orders may depend on past market volatility. Limit orders are stored in the book whereas market orders give immediate birth to transactions. We show that fat tails and volatility clustering are recovered by means of very simple assumptions. We also investigate two important stylized facts of the limit order book, i.e., the distribution of waiting times between two consecutive transactions and the instantaneous price impact function. We show both theoretically and through simulations that if the order waiting times are exponentially distributed, even trading waiting times are also exponentially distributed.

  12. A Multiple Auctions Support System BiddingBot based on a Cooperative Bidding Mechanism among Agents

    NASA Astrophysics Data System (ADS)

    Ito, Takayuki; Hattori, Hiromitsu; Shintani, Toramatsu

    Online auctions are becoming an increasingly important channel for electronic commerce. There are a number of online auction sites on the Internet. It is hard for users to attend, monitor, and make bids at simultaneous multiple auctions. In this paper, we implement BiddingBot which is a multiagent system that supports users in attending, monitoring, and bidding in multiple auctions. Further, we propose a new cooperative bidding mechanism among agents. Our current experiment demonstrates that our new cooperative bidding mechanism can effectively support users to monitor, attend, and make bids on multiple simultaneous auctions.

  13. AUCTION MECHANISMS FOR IMPLEMENTING TRADABLE NETWORK PERMIT MARKETS

    NASA Astrophysics Data System (ADS)

    Wada, Kentaro; Akamatsu, Takashi

    This paper proposes a new auction mechanism for implementing the tradable network permit markets. Assuming that each user makes a trip from an origin to a destination along a path in a specific time period, we design an auction mechanism that enables each user to purchase a bundle of permits corresponding to a set of links in the user's preferred path. The objective of the proposed mechanism is to achieve a socially optimal state with minimal revelation of users' private information. In order to achieve this, the mechanism employs an evolutionary approach that has an auction phase and a path capacity adjustment phase, which are repeated on a day-to-day basis. We prove that the proposed mechanism has the following desirable properties: (1) truthful bidding is the dominant strategy for each user and (2) the proposed mechanism converges to an approximate socially optimal state in the sense that the achieved value of the social surplus reaches its maximum value when the number of users is large.

  14. Competitive Financing Mechanisms: Auctions Used by Federal Agencies.

    ERIC Educational Resources Information Center

    Joyner, Carlotta C.

    This report reviews auctions used by various federal agencies to examine the feasibility of using similar auctions to determine interest rates for student borrowing through the Federal Family Education Loan Program (FFELP) and the William D. Ford Federal Direct Loan Program. The review identified 31 different auctions, divided into two major…

  15. A False-name-Proof Double Auction Protocol for Arbitrary Evaluation Values

    NASA Astrophysics Data System (ADS)

    Sakurai, Yuko; Yokoo, Makoto

    We develop a new false-name-proof double auction protocol called the Generalized Threshold Price Double auction (GTPD) protocol. False-name-proofness generalizes strategy-proofness by incorporating the possibility of false-name bids, e.g., bids submitted using multiple e-mail addresses. An existing protocol called TPD protocol is false-name-proof but can handle only the cases where marginal utilities of each agent always decrease, while our new GTPD protocol can handle arbitrary evaluation values. When marginal utilities can increase, some bids cannot be divided into a single unit (e.g., an all-or-nothing bid). Due to the existence of such indivisible bids, meeting supply/demand becomes difficult. Furthermore, a seller/buyer can submit a false-name-bid by pretending to be a potential buyer/seller to manipulate allocations and payments. In the GTPD protocol, the auctioneer is required to absorb the supply-demand imbalance up to a given upper-bound. Also, the GTPD incorporate a new false-name-proof one-sided auction protocol that is guaranteed to sell/buy a certain number of units. Simulation results show that when the threshold price is set appropriately, this protocol can obtain a good social surplus, and the number of absorbed units is much smaller than the given upper-bound.

  16. Learning Based Bidding Strategy for HVAC Systems in Double Auction Retail Energy Markets

    SciTech Connect

    Sun, Yannan; Somani, Abhishek; Carroll, Thomas E.

    2015-07-01

    In this paper, a bidding strategy is proposed using reinforcement learning for HVAC systems in a double auction market. The bidding strategy does not require a specific model-based representation of behavior, i.e., a functional form to translate indoor house temperatures into bid prices. The results from reinforcement learning based approach are compared with the HVAC bidding approach used in the AEP gridSMART® smart grid demonstration project and it is shown that the model-free (learning based) approach tracks well the results from the model-based behavior. Successful use of model-free approaches to represent device-level economic behavior may help develop similar approaches to represent behavior of more complex devices or groups of diverse devices, such as in a building. Distributed control requires an understanding of decision making processes of intelligent agents so that appropriate mechanisms may be developed to control and coordinate their responses, and model-free approaches to represent behavior will be extremely useful in that quest.

  17. Mechanism Design for Multi-slot Ads Auction in Sponsored Search Markets

    NASA Astrophysics Data System (ADS)

    Deng, Xiaotie; Sun, Yang; Yin, Ming; Zhou, Yunhong

    In this paper, we study pricing models for multi-slot advertisements, where advertisers can bid to place links to their sales webpages at one or multiple slots on a webpage, called the multi-slot AD auction problem. We develop and analyze several important mechanisms, including the VCG mechanism for multi-slot ads auction, the optimal social welfare solution, as well as two weighted GSP-like protocols (mixed and hybrid). Furthermore, we consider that forward-looking Nash equilibrium and prove its existence in the weighted GSP-like pricing protocols.

  18. Comparisons of auction mechanisms in a multiple unit setting: A consideration for restructuring electric power markets

    NASA Astrophysics Data System (ADS)

    Bernard, John Charles

    The objective of this study was to compare the performance of five single sided auctions that could be used in restructured electric power markets across different market sizes in a multiple unit setting. Auction selection would profoundly influence an industry over $200 billion in size in the United States, and the consequences of implementing an inappropriate mechanism would be great. Experimental methods were selected to analyze the auctions. Two rounds of experiments were conducted, the first testing the sealed offer last accepted offer (LAO) and first rejected offer (FRO), and the clock English (ENG) and sealed offer English (SOE) in markets of sizes two and six. The FRO, SOE, and ENG used the same pricing rule. Second round testing was on the LAO, FRO, and the nonuniform price multiple unit Vickrey (MUV) in markets of sizes two, four, and six. Experiments lasted 23 and 75 periods for rounds 1 and 2 respectively. Analysis of variance and contrast analysis were used to examine the data. The four performance measures used were price, efficiency, profits per unit, and supply revelation. Five basic principles were also assessed: no sales at losses, all low cost capacity should be offered and sold, no high cost capacity should sell, and the market should clear. It was expected group size and auction type would affect performance. For all performance measures, group size was a significant variable, with smaller groups showing poorer performance. Auction type was significant only for the efficiency performance measure, where clock auctions outperformed the others. Clock auctions also proved superior for the first four principles. The FRO performed poorly in almost all situations, and should not be a preferred mechanism in any market. The ENG was highly efficient, but expensive for the buyer. The SOE appeared superior to the FRO and ENG. The clock improves efficiency over the FRO while less information kept prices under the ENG. The MUV was superior in revealing costs

  19. Efficient Nash Equilibrium Resource Allocation Based on Game Theory Mechanism in Cloud Computing by Using Auction.

    PubMed

    Nezarat, Amin; Dastghaibifard, G H

    2015-01-01

    One of the most complex issues in the cloud computing environment is the problem of resource allocation so that, on one hand, the cloud provider expects the most profitability and, on the other hand, users also expect to have the best resources at their disposal considering the budget constraints and time. In most previous work conducted, heuristic and evolutionary approaches have been used to solve this problem. Nevertheless, since the nature of this environment is based on economic methods, using such methods can decrease response time and reducing the complexity of the problem. In this paper, an auction-based method is proposed which determines the auction winner by applying game theory mechanism and holding a repetitive game with incomplete information in a non-cooperative environment. In this method, users calculate suitable price bid with their objective function during several round and repetitions and send it to the auctioneer; and the auctioneer chooses the winning player based the suggested utility function. In the proposed method, the end point of the game is the Nash equilibrium point where players are no longer inclined to alter their bid for that resource and the final bid also satisfies the auctioneer's utility function. To prove the response space convexity, the Lagrange method is used and the proposed model is simulated in the cloudsim and the results are compared with previous work. At the end, it is concluded that this method converges to a response in a shorter time, provides the lowest service level agreement violations and the most utility to the provider. PMID:26431035

  20. Emergence of Cooperative Long-Term Market Loyalty in Double Auction Markets

    PubMed Central

    Alorić, Aleksandra; Sollich, Peter; McBurney, Peter; Galla, Tobias

    2016-01-01

    Loyal buyer-seller relationships can arise by design, e.g. when a seller tailors a product to a specific market niche to accomplish the best possible returns, and buyers respond to the dedicated efforts the seller makes to meet their needs. We ask whether it is possible, instead, for loyalty to arise spontaneously, and in particular as a consequence of repeated interaction and co-adaptation among the agents in a market. We devise a stylized model of double auction markets and adaptive traders that incorporates these features. Traders choose where to trade (which market) and how to trade (to buy or to sell) based on their previous experience. We find that when the typical scale of market returns (or, at fixed scale of returns, the intensity of choice) become higher than some threshold, the preferred state of the system is segregated: both buyers and sellers are segmented into subgroups that are persistently loyal to one market over another. We characterize the segregated state analytically in the limit of large markets: it is stabilized by some agents acting cooperatively to enable trade, and provides higher rewards than its unsegregated counterpart both for individual traders and the population as a whole. PMID:27120473

  1. Emergence of Cooperative Long-Term Market Loyalty in Double Auction Markets.

    PubMed

    Alorić, Aleksandra; Sollich, Peter; McBurney, Peter; Galla, Tobias

    2016-01-01

    Loyal buyer-seller relationships can arise by design, e.g. when a seller tailors a product to a specific market niche to accomplish the best possible returns, and buyers respond to the dedicated efforts the seller makes to meet their needs. We ask whether it is possible, instead, for loyalty to arise spontaneously, and in particular as a consequence of repeated interaction and co-adaptation among the agents in a market. We devise a stylized model of double auction markets and adaptive traders that incorporates these features. Traders choose where to trade (which market) and how to trade (to buy or to sell) based on their previous experience. We find that when the typical scale of market returns (or, at fixed scale of returns, the intensity of choice) become higher than some threshold, the preferred state of the system is segregated: both buyers and sellers are segmented into subgroups that are persistently loyal to one market over another. We characterize the segregated state analytically in the limit of large markets: it is stabilized by some agents acting cooperatively to enable trade, and provides higher rewards than its unsegregated counterpart both for individual traders and the population as a whole. PMID:27120473

  2. A Centralized Auction Mechanism for the Disability and Survivors Insurance in Chile

    NASA Astrophysics Data System (ADS)

    Reyes H., Gonzalo

    As part of the pension reform recently approved in Chile, the government introduced a centralized auction mechanism to provide the Disability and Survivors (D&S) Insurance that covers recent contributors among the more than 8 million participants in the mandatory private pension system. This paper is intended as a case study presenting the main distortions found in the decentralized operation of the system that led to this reform and the challenges faced when designing a competitive auction mechanism to be implemented jointly by the Pension Fund Managers (AFP). In a typical bilateral contract the AFP retained much of the risk and the Insurance Company acted in practice as a reinsurer. The process to hire this contract was not competitive and colligated companies ended up providing the service. Several distortions affected competition in the market through incentives to cream-skim members by AFPs (since they bear most of the risk) or efforts to block disability claims. Since the price of this insurance is hidden in the fees charged by AFPs for the administration of individual accounts and pension funds there was lack of price transparency. Since new AFPs have no history of members’ disability and mortality profile the insurance contract acted as a barrier to entry in the market of AFP services, especially when D&S insurance costs reached 50% of total costs. Cross-subsidies between members of the same AFP, inefficient risk pooling (due to pooling occurring at the AFP rather than at the system level) and regulatory arbitrage, since AFPs provided insurance not being regulated as an insurance company, were also present. A centralized auction mechanism solves these market failures, but also gives raise to new challenges, such as how to design a competitive auction that attracts participation and deters collusion. Design features that were incorporated in the regulation to tackle these issues, such as dividing coverage into predefined percentage blocks, are presented

  3. Efficient Nash Equilibrium Resource Allocation Based on Game Theory Mechanism in Cloud Computing by Using Auction

    PubMed Central

    Nezarat, Amin; Dastghaibifard, GH

    2015-01-01

    One of the most complex issues in the cloud computing environment is the problem of resource allocation so that, on one hand, the cloud provider expects the most profitability and, on the other hand, users also expect to have the best resources at their disposal considering the budget constraints and time. In most previous work conducted, heuristic and evolutionary approaches have been used to solve this problem. Nevertheless, since the nature of this environment is based on economic methods, using such methods can decrease response time and reducing the complexity of the problem. In this paper, an auction-based method is proposed which determines the auction winner by applying game theory mechanism and holding a repetitive game with incomplete information in a non-cooperative environment. In this method, users calculate suitable price bid with their objective function during several round and repetitions and send it to the auctioneer; and the auctioneer chooses the winning player based the suggested utility function. In the proposed method, the end point of the game is the Nash equilibrium point where players are no longer inclined to alter their bid for that resource and the final bid also satisfies the auctioneer’s utility function. To prove the response space convexity, the Lagrange method is used and the proposed model is simulated in the cloudsim and the results are compared with previous work. At the end, it is concluded that this method converges to a response in a shorter time, provides the lowest service level agreement violations and the most utility to the provider. PMID:26431035

  4. Reputation mechanism: From resolution for truthful online auctions to the model of optimal one-gambler problem

    SciTech Connect

    Bradonjic, Milan

    2009-01-01

    In this paper we study reputation mechanisms, and show how the notion of reputation can help us in building truthful online auction mechanisms. From the mechanism design prospective, we derive the conditions on and design a truthful online auction mechanism. Moreover, in the case when some agents may lay or cannot have the real knowledge about the other agents reputations, we derive the resolution of the auction, such that the mechanism is truthful. Consequently, we move forward to the optimal one-gambler/one-seller problem, and explain how that problem is refinement of the previously discussed online auction design in the presence of reputation mechanism. In the setting of the optimal one-gambler problem, we naturally rise and solve the specific question: What is an agent's optimal strategy, in order to maximize his revenue? We would like to stress that our analysis goes beyond the scope, which game theory usually discusses under the notion of reputation. We model one-player games, by introducing a new parameter (reputation), which helps us in predicting the agent's behavior, in real-world situations, such as, behavior of a gambler, real-estate dealer, etc.

  5. Three essays on auction markets

    NASA Astrophysics Data System (ADS)

    Shunda, Nicholas James

    This dissertation contains a series of theoretical investigations of auction markets. The essays it contains cover wholesale electricity markets, a popular selling mechanism on eBay, and supplier entry into multi-unit procurement auctions. The study in Chapter 1 compares the procurement cost-minimizing and productive efficiency performance of the auction mechanism used by independent system operators in wholesale electricity auction markets in the U.S. with that of a proposed alternative. The current practice allocates energy contracts as if the auction featured a discriminatory final payment method when, in fact, the markets are uniform price auctions. The proposed alternative explicitly accounts for the market-clearing price during the allocation phase. We find that the proposed alternative largely outperforms the current practice on the basis of procurement costs in the context of simple auction markets featuring both day-ahead and real-time auctions and that the procurement cost advantage of the alternative is complete when we simulate the effects of increased competition. We also find that a tradeoff between the objectives of procurement cost minimization and productive efficiency emerges in our simple auction markets and persists in the face of increased competition. The study in Chapter 2 considers a possible rationale for an auction with a buy price. In an auction with a buy price, the seller provides bidders with an option to end the auction early by accepting a transaction at a posted price. The "Buy-It-Now" option on eBay is a leading example of an auction with a buy price. The study develops a model of an auction with a buy price in which bidders use the auction's reserve price and buy price to formulate a reference price. The model both explains why a revenue-maximizing seller would want to augment her auction with a buy price and demonstrates that the seller sets a higher reserve price when she can affect the bidders' reference price through the

  6. Auctioning Airport Slots?

    NASA Technical Reports Server (NTRS)

    Gruyer, Nicolas; Lenoir, Nathalie

    2003-01-01

    The current allocation of slots on congested European airports constitutes an obstacle to the effective liberalisation of air transportation undertaken in Europe. With a view to favouring effluent slot utilisation and competition, as is the goal of the Euopean commission, we propose to use a market mechanism, based on temporary" utilisation licences. In order to allocate those licences, we propose and describe an iterated combinatorial auction mechanism where a percentage of licences would be reallocated each season. A secondary market would also be set up in order to reallocate slots during a season. Since a combinatorial auction involve a complex optimisation procedure, we describe how it can be made to work in the case of auctions.

  7. Secure quantum sealed-bid auction with post-confirmation

    NASA Astrophysics Data System (ADS)

    Zhao, Zhiwen; Naseri, Mosayeb; Zheng, Yuanqing

    2010-08-01

    A new secure quantum auction with post-confirmation is proposed, which is a direct application of the multi-particle super dense coding scheme to the auction problem. In this scheme all bidders use M groups n-particle GHZ states to represent their bids. Different from classical auction protocols and the previous secure quantum sealed-bid auction protocols, in the present scheme, by introducing a post-confirmation mechanism the honesty of the quantum sealed-bid auction is guaranteed, i.e., malicious bidders cannot collude with auctioneers. Also by sharing secret keys with the bidders the auctioneer could insure the anonymity of the bidders.

  8. Anonymous, Yet Trustworthy Auctions

    NASA Astrophysics Data System (ADS)

    Chanda, Prasit Bikash; Naessens, Vincent; de Decker, Bart

    An auction is an inevitable market mechanism to setup prices of goods or services in a competitive and dynamic environment. Anonymity of bidders is required to conceal their business strategies from competitors. However, it is also essential to provide the seller guarantees that a bidder is trustworthy and competent enough to perform certain tasks (e.g transports). This paper proposes an auction protocol where bidders will participate anonymously, yet prove to be trustworthy and competent and can be held accountable towards auctioneers and sellers. Moreover, the protocol introduces promises, bonuses and compensations to ensure the best price for the sellers, extra profit for bidders and opportunities for newcomers in the business. It also handles ties, and copes with last minute bidding. Finally, the auction’s fair proceedings and outcome can be verified by everyone.

  9. Double-Swivel Mechanism For Reliable Release

    NASA Technical Reports Server (NTRS)

    King, Guy L.; Schneider, William C.

    1990-01-01

    Double-swivel toggle mechanism releases large, heavy objects reliably. Double-swiveling action of mechanism ensures it clears restraining pins upon release. Pins retain toggle and its load. If pin fails to withdraw at designated time for releasing payload, toggle swivels about its upper ball, and ring swivels about lower ball so ring flange clears failed pin. Double-swivel action ensures disengagement even it two pins fail to withdraw.

  10. Auction-based Security Game for Multiuser Cooperative Networks

    NASA Astrophysics Data System (ADS)

    Wang, An; Cai, Yueming; Yang, Wendong; Cheng, Yunpeng

    2013-04-01

    In this paper, we develop an auction-based algorithm to allocate the relay power efficiently to improve the system secrecy rate in a cooperative network, where several source-destination pairs and one cooperative relay are involved. On the one hand, the cooperative relay assists these pairs to transmit under a peak power constraint. On the other hand, the relay is untrusty and is also a passive eavesdropper. The whole auction process is completely distributed and no instantaneous channel state information exchange is needed. We also prove the existence and uniqueness of the Nash Equilibrium (NE) for the proposed power auction game. Moreover, the Pareto optimality is also validated. Simulation results show that our proposed auction-based algorithm can effectively improve the system secrecy rate. Besides, the proposed auction-based algorithm can converge to the unique NE point within a finite number of iterations. More interestingly, we also find that the proposed power auction mechanism is cheat-proof.

  11. Earthquakes with non--double-couple mechanisms.

    PubMed

    Frohlich, C

    1994-05-01

    Seismological observations confirm that the pattern of seismic waves from some earthquakes cannot be produced by slip along a planar fault surface. More than one physical mechanism is required to explain the observed varieties of these non-double-couple earthquakes. The simplest explanation is that some earthquakes are complex, with stress released on two or more suitably oriented, nonparallel fault surfaces. However, some shallow earthquakes in volcanic and geothermal areas require other explanations. Current research focuses on whether fault complexity explains most observed non-double-couple earthquakes and to what extent ordinary earthquakes have non-double-couple components. PMID:17794721

  12. Improved secure quantum sealed-bid auction

    NASA Astrophysics Data System (ADS)

    Yang, Yu-Guang; Naseri, Mosayeb; Wen, Qiao-Yan

    2009-10-01

    The security of a secure quantum sealed-bid auction protocol using quantum secure direct communication based on GHZ states [M. Naseri, Opt. Commun. 282 (2009) 1939] is reexamined. It is shown that the protocol does not complete the task of a sealed-bid auction fairly. It is shown that a dishonest bidder can obtain all the other one's secret bids by two special types of attack, i.e., double Controlled NOT attack or using fake entangled particles. Furthermore, a simple possible improvement of the protocol is proposed.

  13. Essays on wholesale auctions in deregulated electricity markets

    NASA Astrophysics Data System (ADS)

    Baltaduonis, Rimvydas

    2007-12-01

    The early experience in the restructured electric power markets raised several issues, including price spikes, inefficiency, security, and the overall relationship of market clearing prices to generation costs. Unsatisfactory outcomes in these markets are thought to have resulted in part from strategic generator behaviors encouraged by inappropriate market design features. In this dissertation, I examine the performance of three auction mechanisms for wholesale power markets - Offer Cost Minimization auction, Payment Cost Minimization auction and Simple-Offer auction - when electricity suppliers act strategically. A Payment Cost Minimization auction has been proposed as an alternative to the traditional Offer Cost Minimization auction with the intention to solve the problem of inflated wholesale electricity prices. Efficiency concerns for this proposal were voiced due to insights predicated on the assumption of true production cost revelation. Using a game theoretic approach and an experimental method, I compare the two auctions, strictly controlling for the level of unilateral market power. A specific feature of these complex-offer auctions is that the sellers submit not only the quantities and the minimum prices that they are willing to sell at, but also the start-up fees, which are designed to reimburse the fixed start-up costs of the generation plants. I find that the complex structure of the offers leaves considerable room for strategic behavior, which consequently leads to anti-competitive and inefficient market outcomes. In the last chapter of my dissertation, I use laboratory experiments to contrast the performance of two complex-offer auctions against the performance of a simple-offer auction, in which the sellers have to recover all their generation costs - fixed and variable - through a uniform market-clearing price. I find that a simple-offer auction significantly reduces consumer prices and lowers price volatility. It mitigates anti-competitive effects

  14. Mechanical response of biopolymer double networks

    NASA Astrophysics Data System (ADS)

    Carroll, Joshua; Das, Moumita

    We investigate a double network model of articular cartilage (AC) and characterize its equilibrium mechanical response. AC has very few cells and the extracellular matrix mainly determines its mechanical response. This matrix can be thought of as a double polymer network made of collagen and aggrecan. The collagen fibers are stiff and resist tension and compression forces, while aggrecans are flexible and control swelling and hydration. We construct a microscopic model made of two interconnected disordered polymer networks, with fiber elasticity chosen to qualitatively mimic the experimental system. We study the collective mechanical response of this double network as a function of the concentration and stiffness of the individual components as well as the strength of the connection between them using rigidity percolation theory. Our results may provide a better understanding of mechanisms underlying the mechanical resilience of AC, and more broadly may also lead to new perspectives on the mechanical response of multicomponent soft materials. This work was partially supported by a Cottrell College Science Award.

  15. Approximating the Qualitative Vickrey Auction by a Negotiation Protocol

    NASA Astrophysics Data System (ADS)

    Hindriks, Koen V.; Tykhonov, Dmytro; de Weerdt, Mathijs

    A result of Bulow and Klemperer has suggested that auctions may be a better tool to obtain an efficient outcome than negotiation. For example, some auction mechanisms can be shown to be efficient and strategy-proof. However, they generally also require that the preferences of at least one side of the auction are publicly known. However, sometimes it is very costly, impossible, or undesirable to publicly announce such preferences. It thus is interesting to find methods that do not impose this constraint but still approximate the outcome of the auction. In this paper we show that a multi-round multi-party negotiation protocol may be used to this end if the negotiating agents are capable of learning opponent preferences. The latter condition can be met by current state of the art negotiation technology. We show that this protocol approximates the theoretical outcome predicted by a so-called Qualitative Vickrey auction mechanism (even) on a complex multi-issue domain.

  16. A novel mechanism for creating double pulsars

    NASA Technical Reports Server (NTRS)

    Sigurdsson, Steinn; Hernquist, Lars

    1992-01-01

    Simulations of encounters between pairs of hard binaries, each containing a neutron star and a main-sequence star, reveal a new formation mechanism for double pulsars in dense cores of globular clusters. In many cases, the two normal stars are disrupted to form a common envelope around the pair of neutron stars, both of which will be spun up to become millisecond pulsars. We predict that a new class of pulsars, double millisecond pulsars, will be discovered in the cores of dense globular clusters. The genesis proceeds through a short-lived double-core common envelope phase, with the envelope ejected in a fast wind. It is possible that the progenitor may also undergo a double X-ray binary phase. Any circular, short-period double pulsar found in the galaxy would necessarily come from disrupted disk clusters, unlike Hulse-Taylor class pulsars or low-mass X-ray binaries which may be ejected from clusters or formed in the galaxy.

  17. Quantum English auctions

    NASA Astrophysics Data System (ADS)

    Piotrowski, Edward W.; Sładkowski, Jan

    2003-02-01

    We continue the analysis of quantum-like description of markets and economics. The approach has roots in the recently developed quantum game theory and quantum computing. The present paper is devoted to quantum English auction which we consider as a special class of quantum market games. The approach allows to calculate profit intensities for various possible strategies.

  18. Bandwidth auction for SVC streaming in dynamic multi-overlay

    NASA Astrophysics Data System (ADS)

    Xiong, Yanting; Zou, Junni; Xiong, Hongkai

    2010-07-01

    In this paper, we study the optimal bandwidth allocation for scalable video coding (SVC) streaming in multiple overlays. We model the whole bandwidth request and distribution process as a set of decentralized auction games between the competing peers. For the upstream peer, a bandwidth allocation mechanism is introduced to maximize the aggregate revenue. For the downstream peer, a dynamic bidding strategy is proposed. It achieves maximum utility and efficient resource usage by collaborating with a content-aware layer dropping/adding strategy. Also, the convergence of the proposed auction games is theoretically proved. Experimental results show that the auction strategies can adapt to dynamic join of competing peers and video layers.

  19. A Study of Central Auction Based Wholesale Electricity Markets

    NASA Astrophysics Data System (ADS)

    Ceppi, Sofia; Gatti, Nicola

    The deregulation of electricity markets produced significant economic benefits, reducing prices to customers and opening several opportunities for new actors, e.g., new generators and distributors. A prominent scientific and technological challenge is the automation of such markets. In particular, we focus our attention on wholesale electricity markets based on a central auction. In these markets, generators sell electricity by means of a central auction to a public authority. Instead, the distribution of electricity to customers takes part in retail markets. The main works presented in the literature model wholesale markets as oligopolies, neglecting thus the specific auction mechanism. In this paper, we enrich these models by introducing an auction mechanism shaped on that used in the Italian wholesale electricity market, we solve the winner determination problem, and we preliminarily study the problem of searching for equilibria.

  20. Adaptive Techniques for Online Auctions

    SciTech Connect

    Sakas, D. P.; Vlachos, D. S.; Simos, T. E.

    2007-12-26

    Online auctions consider a setting in which agents arrive dynamically and require that an allocation and payment decision is made before they depart. An auctioneer must take a decision having no knowledge about the time horizon and the strategy of the bidder agent. In this work, we present an utility theory based model which is capable of taking the auctioneer decision and adopt its assumptions about the bidders from the results of past auctions. Simulation results are presented in order to test the efficiency of the proposed model.

  1. Adaptive Techniques for Online Auctions

    NASA Astrophysics Data System (ADS)

    Sakas, D. P.; Vlachos, D. S.; Simos, T. E.

    2007-12-01

    Online auctions consider a setting in which agents arrive dynamically and require that an allocation and payment decision is made before they depart. An auctioneer must take a decision having no knowledge about the time horizon and the strategy of the bidder agent. In this work, we present an utility theory based model which is capable of taking the auctioneer decision and adopt its assumptions about the bidders from the results of past auctions. Simulation results are presented in order to test the efficiency of the proposed model.

  2. Cryptanalysis and melioration of secure quantum sealed-bid auction with post-confirmation

    NASA Astrophysics Data System (ADS)

    He, Li-Bao; Huang, Liu-Sheng; Yang, Wei; Xu, Rui; Han, Dian-Qi

    2012-12-01

    We investigate the quantum sealed-bid auction protocol proposed by Zhao et al. (Opt Commun 283:1394, 2010). It uses M groups n-particle GHZ states to represent bids and a post-confirmation mechanism to guarantee the honesty of the quantum sealed-bid auction. However, in our opinion the protocol still does not complete the task of a sealed-bid auction fairly. It is shown that a large group of dishonest bidders can collude to obtain all the other one's secret bids before the opening phase of the auction with a probability polynomially close to one. Moreover, a simple feasible improvement of the protocol is proposed.

  3. The Double Cone: A Mechanical Paradox or a Geometrical Constraint?

    ERIC Educational Resources Information Center

    Gallitto, Aurelio Agliolo; Fiordilino, Emilio

    2011-01-01

    In the framework of the Italian National Plan "Lauree Scientifiche" (PLS) in collaboration with secondary schools, we have investigated the mechanical paradox of the double cone. We have calculated the geometric condition for obtaining an upward movement. Based on this result, we have built a mechanical model with a double cone made of aluminum…

  4. Mechanical seal having a double-tier mating ring

    DOEpatents

    Khonsari, Michael M.; Somanchi, Anoop K.

    2005-09-13

    An apparatus and method to enhance the overall performance of mechanical seals in one of the following ways: by reducing seal face wear, by reducing the contact surface temperature, or by increasing the life span of mechanical seals. The apparatus is a mechanical seal (e.g., single mechanical seals, double mechanical seals, tandem mechanical seals, bellows, pusher mechanical seals, and all types of rotating and reciprocating machines) comprising a rotating ring and a double-tier mating ring. In a preferred embodiment, the double-tier mating ring comprises a first and a second stationary ring that together form an agitation-inducing, guided flow channel to allow for the removal of heat generated at the seal face of the mating ring by channeling a coolant entering the mating ring to a position adjacent to and in close proximity with the interior surface area of the seal face of the mating ring.

  5. Mechanically tough, elastic and stable rope-like double nanohelices

    NASA Astrophysics Data System (ADS)

    Dai, L.; Huang, X. J.; Dong, L. X.; Zhang, Q.; Zhang, L.

    2014-07-01

    Double helix nanostructures have been the object of intense theoretical and experimental investigations in recent years due to their various types of available materials and unique morphology. Among these structures, rope-like double nanohelices of two strands in contact along a line can be obtained using any one-dimensional nanostructure. In this work, we establish a novel theory for quantitatively exploring the statics and dynamics of rope-like double nanohelices by employing the concept of the extensible Cosserat curve. The rope-like double nanohelices are tough, relatively elastic, and mechanically stable, which agrees well with the experiments. The characteristics of the interaction between the two strands, the tensile modulus and the torque are precisely described and explained across the entire stretching region. The proposed model offers in depth quantitative insight into the mechanics of double helix nanostructures, and supplies a reliable reference for further experimental research.

  6. 76 FR 81932 - Auction of FM Broadcast Construction Permits; Revised Construction Permit Number in Auction 93

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... listed in Attachment A to the Auction 93 Procedures Public Notice, 76 FR 78645, December 19, 2011, to MM... COMMISSION Auction of FM Broadcast Construction Permits; Revised Construction Permit Number in Auction 93... the construction permit number for one of the FM broadcast construction permits for Auction 93....

  7. 7 CFR 46.25 - Auction sales.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Auction sales. 46.25 Section 46.25 Agriculture... THAN RULES OF PRACTICE) UNDER THE PERISHABLE AGRICULTURAL COMMODITIES ACT, 1930 Auction Sales § 46.25 Auction sales. Commission merchants, dealers and brokers who offer produce for sale through...

  8. Internet Auction Sellers: Does Size Really Matter?

    ERIC Educational Resources Information Center

    Halstead, Diane; Becherer, Richard C.

    2003-01-01

    Examines the Internet auction phenomenon as it relates to the marketing mix of online auction sellers. The data indicate that, while there is great diversity among businesses that utilize online auctions, distinct cost leadership and differentiation marketing strategies are both evident. These two approaches are further distinguished in terms of…

  9. 40 CFR 73.70 - Auctions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... such offers will be sold to cover the bids, according to each such offeror's pro rata share of all... each auction, the Administrator will pay a pro rata share of the proceeds of each auction to the... withheld for the purposes of establishing the Auction Subaccount. Each unit's pro rata share will...

  10. Exploring Online Auction Behaviors and Motivations

    ERIC Educational Resources Information Center

    Jeon, Sua; Crutsinger, Christy; Kim, Haejung

    2008-01-01

    The availability and convenience of the Internet, combined with the variety of products available at any given time, have contributed to the success of online auctions.This exploratory study examined online auction behaviors among college students in an attempt to identify underlying dimensions of auction motivations. Questionnaires completed by…

  11. Statistical Properties of Online Auctions

    NASA Astrophysics Data System (ADS)

    Namazi, Alireza; Schadschneider, Andreas

    We characterize the statistical properties of a large number of online auctions run on eBay. Both stationary and dynamic properties, like distributions of prices, number of bids etc., as well as relations between these quantities are studied. The analysis of the data reveals surprisingly simple distributions and relations, typically of power-law form. Based on these findings we introduce a simple method to identify suspicious auctions that could be influenced by a form of fraud known as shill bidding. Furthermore the influence of bidding strategies is discussed. The results indicate that the observed behavior is related to a mixture of agents using a variety of strategies.

  12. Biological auctions with multiple rewards

    PubMed Central

    Reiter, Johannes G.; Kanodia, Ayush; Gupta, Raghav; Nowak, Martin A.; Chatterjee, Krishnendu

    2015-01-01

    The competition for resources among cells, individuals or species is a fundamental characteristic of evolution. Biological all-pay auctions have been used to model situations where multiple individuals compete for a single resource. However, in many situations multiple resources with various values exist and single reward auctions are not applicable. We generalize the model to multiple rewards and study the evolution of strategies. In biological all-pay auctions the bid of an individual corresponds to its strategy and is equivalent to its payment in the auction. The decreasingly ordered rewards are distributed according to the decreasingly ordered bids of the participating individuals. The reproductive success of an individual is proportional to its fitness given by the sum of the rewards won minus its payments. Hence, successful bidding strategies spread in the population. We find that the results for the multiple reward case are very different from the single reward case. While the mixed strategy equilibrium in the single reward case with more than two players consists of mostly low-bidding individuals, we show that the equilibrium can convert to many high-bidding individuals and a few low-bidding individuals in the multiple reward case. Some reward values lead to a specialization among the individuals where one subpopulation competes for the rewards and the other subpopulation largely avoids costly competitions. Whether the mixed strategy equilibrium is an evolutionarily stable strategy (ESS) depends on the specific values of the rewards. PMID:26180069

  13. Multiparty quantum sealed-bid auction using single photons as message carrier

    NASA Astrophysics Data System (ADS)

    Liu, Wen-Jie; Wang, Hai-Bin; Yuan, Gong-Lin; Xu, Yong; Chen, Zhen-Yu; An, Xing-Xing; Ji, Fu-Gao; Gnitou, Gnim Tchalim

    2016-02-01

    In this study, a novel multiparty quantum sealed-bid auction protocol using the single photons as the message carrier of bids is proposed, followed by an example of three-party auction. Compared with those protocols based on the entangled states (GHZ state, EPR pairs, etc.), the present protocol is more economic and feasible within present technology. In order to guarantee the security and the fairness of the auction, the decoy photon checking technique and an improved post-confirmation mechanism with EPR pairs are introduced, respectively.

  14. New mechanisms for double charmed meson production at the LHCb

    NASA Astrophysics Data System (ADS)

    Maciuła, Rafał; Saleev, Vladimir A.; Shipilova, Alexandra V.; Szczurek, Antoni

    2016-07-01

    We discuss production of D0D0 (and Dbar0Dbar0) pairs related to the LHCb Collaboration results for √{ s} = 7 TeV in proton-proton scattering. We consider double-parton scattering (DPS) mechanisms of double c c bar production and subsequent cc →D0D0 hadronization as well as double g and mixed gc c bar production with gg →D0D0 and gc →D0D0 hadronization calculated with the help of the scale-dependent hadronization functions of Kniehl et al. Single-parton scattering (SPS) mechanism of digluon production is also taken into account. We compare our results with several correlation observables in azimuthal angle φD0D0 between D0 mesons or in dimeson invariant mass MD0D0. The inclusion of new mechanisms with g →D0 fragmentation leads to larger cross sections, than when including only DPS mechanism cc →D0D0 with standard scale-independent fragmentation functions. Some consequences of the presence of the new mechanisms are discussed. In particular a larger σeff is needed to describe the LHCb data. There is a signature that σeff may depend on transverse momentum of c quarks and/or c bar antiquarks.

  15. Auctions with Dynamic Populations: Efficiency and Revenue Maximization

    NASA Astrophysics Data System (ADS)

    Said, Maher

    We study a stochastic sequential allocation problem with a dynamic population of privately-informed buyers. We characterize the set of efficient allocation rules and show that a dynamic VCG mechanism is both efficient and periodic ex post incentive compatible; we also show that the revenue-maximizing direct mechanism is a pivot mechanism with a reserve price. We then consider sequential ascending auctions in this setting, both with and without a reserve price. We construct equilibrium bidding strategies in this indirect mechanism where bidders reveal their private information in every period, yielding the same outcomes as the direct mechanisms. Thus, the sequential ascending auction is a natural institution for achieving either efficient or optimal outcomes.

  16. Orientation and mechanical response of elastomers containing double networks

    SciTech Connect

    Roland, C.M.; Santangelo, P.G.; Choi, I.S.; Miller J.B.

    1993-12-31

    Orientation is one of the primary means for increasing the modulus and strength of materials comprised of flexible chain polymers. The incorporation of a double network makes the orientation of a flexible chain polymer thermodynamically stable, thus offering the potential for elastomers with improved physical properties. Birefringence and deuterium NMR results will be presented which indicate that the high residual strains obtained via double network formation are accompanied by surprisingly low levels of molecular orientation. It has been found that the presence of a double network amplifies the modulus, strain crystallizability, and, in conjunction with carbon black reinforcement, the electrical conductivity of rubber. Most intriguing is the fact that the modulus increase may not associate with any increased brittleness, as would result from simply increasing the crosslink density. Mechanisms for the modulus enhancement will be proposed and examined.

  17. Auctions for coastal energy resources

    NASA Astrophysics Data System (ADS)

    Griffin, Robert M.

    It is becoming increasingly common to allocate public resources to the private sector for the purpose of developing these resources. One of the earliest uses of auctions in the U.S. for allocating rights to public resources was in the offshore oil and gas industry. The U.S. Federal government, through the Department of Interior (DOI), has used auctions to allocate development rights to offshore oil and gas resources to the private sector since the 1950's. Since then many things have changed. Oil and gas markets have gone through boom and bust cycles, giant technological advances in extraction and assessment have taken place, and alternative energy based in the coastal zone is now in demand in markets as well. There has been an enormous amount of research into the drivers of bidder behavior in auctions and optimal auction design in the last 60 years as well. Throughout all of this, the DOI has continued to use basically the same exact auction design to allocate oil and gas leases. The U.S. offshore oil and gas resources sold by the Department of Interior have accounted for more than $65 billion in revenue since the program started. These offshore resources are an important source of government revenue and national wealth. Additionally, the expansion of the energy sector offshore has enormous potential for electricity generation in the U.S., estimated by the National Renewable Energy Laboratory as approaching 54 gigawatts by 2030 (U.S. Department of Energy, 2008). Taken together, the DOI controls access to a large part of the future of energy in the U.S. The research herein assesses the auction formats used to allocate both fossil fuels and renewable resources on the Outer Continental Shelf (OCS). The first manuscript looks at the current method used by the DOI to allocate oil and gas leases on the OCS, and is primarily interested in how bidders behave in this environment. Using latent class estimation techniques to separate distinct bidding behavior in a laboratory

  18. Electrical power generation by mechanically modulating electrical double layers.

    PubMed

    Moon, Jong Kyun; Jeong, Jaeki; Lee, Dongyun; Pak, Hyuk Kyu

    2013-01-01

    Since Michael Faraday and Joseph Henry made their great discovery of electromagnetic induction, there have been continuous developments in electrical power generation. Most people today get electricity from thermal, hydroelectric, or nuclear power generation systems, which use this electromagnetic induction phenomenon. Here we propose a new method for electrical power generation, without using electromagnetic induction, by mechanically modulating the electrical double layers at the interfacial areas of a water bridge between two conducting plates. We find that when the height of the water bridge is mechanically modulated, the electrical double layer capacitors formed on the two interfacial areas are continuously charged and discharged at different phases from each other, thus generating an AC electric current across the plates. We use a resistor-capacitor circuit model to explain the results of this experiment. This observation could be useful for constructing a micro-fluidic power generation system in the near future. PMID:23403587

  19. Secure quantum sealed-bid auction

    NASA Astrophysics Data System (ADS)

    Naseri, Mosayeb

    2009-05-01

    A new experimentally feasible and secure quantum sealed-bid auction protocol using quantum secure direct communication based on GHZ states is proposed. In this scheme all bidders Bob, Charlie, … , and Zach use M groups n-particle GHZ states to represent their bids. Here, an auctioneer gives the auction outcome by performing a sequence of n-particle GHZ-basis measurements on the final quantum states. It has been shown that using this method guarantees the honesty of the protocol, and malicious bidders can not collude with the auctioneers.

  20. Learning from California`s QF auction

    SciTech Connect

    Gribik, P.

    1995-04-15

    California`s 1993 qualifying facility (QF) auction dramatically illustrates problems that can be encountered in structuring auctions for electric utility solicitations of supply-side resources from qualifying cogeneration and small power production facilities. In the 1993 California QF auction, three California utilities were to select QFs that would be awarded long-term purchased-power contracts. The auction produced some unexpected outcomes that could potentially cost the utilities and their customers tens of millions of dollars per year. A year after the auction was held, the parties were still attempting to revise contracts, or even rebid a portion of the auction. And all of this effort may come to naught, depending upon what happens now that the Federal Energy Regulatory Commission has struck down the auction process under California`s Biennial Resource Plan Update, claiming that it violates the Public Utility Regulatory Policies Act (PURPA) by using an improper method to calculate avoided costs. A study of the California QF auction illustrates yet again that the devil is in the details. And the stakes will only rise farther as regulators in other states rely more on auctions to open up the electric industry to further competition.

  1. Immune Mechanism: A ‘Double-Edged Sword’

    PubMed Central

    Musa, Mustaffa

    2013-01-01

    Immunology has now developed into an independent discipline in medicine which covers not only germ infection which is related to immunity solely but also covers a lot of non-infectious diseases such as autoimmune disease, allergies, and others. Therefore, “The Immune Mechanism: “A Double-Edged Sword” means that the immune mechanism (consisted of antibody mediated mechanism and T cell mediated mechanism), just like one edge playing the role of giving benefit (immunity) as it destroys the agent of infection, and another one can be detrimental as it will cause tissue/cell damages and then give rise to immune diseases (immunopathology). Now, the prevalence of these immune diseases is on the rise and has become a new challenge to our country towards developed country in 2020. Therefore, we have to make ample preparation (laboratory facilities/services, main power, and research) from now on in order to face the problems and challenges. PMID:23966827

  2. 7 CFR 29.36 - Auction market.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Auction market. 29.36 Section 29.36 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.36 Auction market. A place to which tobacco is delivered by...

  3. 7 CFR 29.36 - Auction market.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Auction market. 29.36 Section 29.36 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.36 Auction market. A place to which tobacco is delivered by...

  4. 7 CFR 29.36 - Auction market.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 2 2012-01-01 2012-01-01 false Auction market. 29.36 Section 29.36 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.36 Auction market. A place to which tobacco is delivered by...

  5. 7 CFR 29.36 - Auction market.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Auction market. 29.36 Section 29.36 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.36 Auction market. A place to which tobacco is delivered by...

  6. 7 CFR 29.36 - Auction market.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Auction market. 29.36 Section 29.36 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.36 Auction market. A place to which tobacco is delivered by...

  7. Collusion in Auctions for Emission Permits: An Experimental Analysis

    ERIC Educational Resources Information Center

    Burtraw, Dallas; Goeree, Jacob; Holt, Charles A.; Myers, Erica; Palmer, Karen; Shobe, William

    2009-01-01

    Environmental markets have several institutional features that provide a new context for the use of auctions and that have not been studied previously. This paper reports on laboratory experiments testing three auction forms--uniform and discriminatory price sealed-bid auctions and an ascending clock auction. We test the ability of subjects to…

  8. The beginning of a seed: regulatory mechanisms of double fertilization

    PubMed Central

    Bleckmann, Andrea; Alter, Svenja; Dresselhaus, Thomas

    2014-01-01

    The launch of seed development in flowering plants (angiosperms) is initiated by the process of double fertilization: two male gametes (sperm cells) fuse with two female gametes (egg and central cell) to form the precursor cells of the two major seed components, the embryo and endosperm, respectively. The immobile sperm cells are delivered by the pollen tube toward the ovule harboring the female gametophyte by species-specific pollen tube guidance and attraction mechanisms. After pollen tube burst inside the female gametophyte, the two sperm cells fuse with the egg and central cell initiating seed development. The fertilized central cell forms the endosperm while the fertilized egg cell, the zygote, will form the actual embryo and suspensor. The latter structure connects the embryo with the sporophytic maternal tissues of the developing seed. The underlying mechanisms of double fertilization are tightly regulated to ensure delivery of functional sperm cells and the formation of both, a functional zygote and endosperm. In this review we will discuss the current state of knowledge about the processes of directed pollen tube growth and its communication with the synergid cells resulting in pollen tube burst, the interaction of the four gametes leading to cell fusion and finally discuss mechanisms how flowering plants prevent multiple sperm cell entry (polyspermy) to maximize their reproductive success. PMID:25309552

  9. Double-exchange mechanism in rare-earth compounds

    SciTech Connect

    Gulacsi, M.

    2015-03-15

    We show that double-exchange mechanism is responsible for ferromagnetism in low dimensional rare-earth compounds. We use the bosonized version of the one-dimensional Anderson lattice model in Toulouse limit to characterize the properties of the emerging ferromagnetic phase. We give a comprehensive description of the ferromagnetic ordering of the correlated electrons which appears at intermediate couplings and doping. The obtained ferromagnetic phase transitions have been identified to be an order–disorder transition of the quantum random transverse-field Ising type.

  10. Electrical Power Generation by Mechanically Modulating Electrical Double Layers

    NASA Astrophysics Data System (ADS)

    Pak, Hyuk Kyu; Moon, Jong Kyun

    2014-11-01

    Since Michael Faraday and Joseph Henry made their great discovery of electromagnetic induction, there have been continuous developments in electrical power generation. Most people today get electricity from thermal, hydroelectric, or nuclear power generation systems, which use this electromagnetic induction phenomenon. Here we propose a new method for electrical power generation, without using electromagnetic induction, by mechanically modulating the electrical double layers at the interfacial areas of a water bridge between two conducting plates. We find that when the height of the water bridge is mechanically modulated, the electrical double layer capacitors formed on the two interfacial areas are continuously charged and discharged at different phases from each other, thus generating an AC electric current across the plates. We use a resistor-capacitor circuit model to explain the results of this experiment. This observation could be useful for constructing a micro-fluidic power generation system and for understanding the interfacial charge distribution in solid-liquid interfaces in the near future. This work was supported by Center for Soft and Living Matter through IBS prgram in Korea.

  11. Single-Parameter Combinatorial Auctions with Partially Public Valuations

    NASA Astrophysics Data System (ADS)

    Goel, Gagan; Karande, Chinmay; Wang, Lei

    We consider the problem of designing truthful auctions, when the bidders' valuations have a public and a private component. In particular, we consider combinatorial auctions where the valuation of an agent i for a set S of items can be expressed as v i f(S), where v i is a private single parameter of the agent, and the function f is publicly known. Our motivation behind studying this problem is two-fold: (a) Such valuation functions arise naturally in the case of ad-slots in broadcast media such as Television and Radio. For an ad shown in a set S of ad-slots, f(S) is, say, the number of unique viewers reached by the ad, and v i is the valuation per-unique-viewer. (b) From a theoretical point of view, this factorization of the valuation function simplifies the bidding language, and renders the combinatorial auction more amenable to better approximation factors. We present a general technique, based on maximal-in-range mechanisms, that converts any α-approximation non-truthful algorithm (α ≤ 1) for this problem into Ω(α/log{n}) and Ω(α)-approximate truthful mechanisms which run in polynomial time and quasi-polynomial time, respectively.

  12. Sequential Auctions in Uncertain Information Settings

    NASA Astrophysics Data System (ADS)

    Fatima, Shaheen; Wooldridge, Michael; Jennings, Nicholas R.

    This paper analyzes sequential auctions for private value objects using second-price sealed-bid rules. Now, the equilibrium bids for such auctions depend on the information uncertainty of the bidders. Specifically, there are three key auction parameters that the bidders could be uncertain about: the valuations of the objects for sale, the number of objects for sale, and the number of participating bidders. We analyse the bidding behaviour for each of these three sources of uncertainty. For each setting, we first find the equilibrium bidding strategies for the individual auctions that comprise a series. Then we analyze the effect of these uncertainties on the computational and economic properties of the equilibrium solution. The former analysis is essential if we want to use software agents to bid on our behalf. The latter is essential because both the auctioneer and the bidders want to know how these uncertainties affect their profits. Thus we compare the outcomes for these settings from the perspective of the bidders (i.e., in terms of their profits), from the perspective of the auctioneer (i.e., in terms of his revenue), and from a global perspective (i.e., in terms of auction efficiency).

  13. Quantum auctions: Facts and myths

    NASA Astrophysics Data System (ADS)

    Piotrowski, Edward W.; Sładkowski, Jan

    2008-06-01

    Quantum game theory, whatever opinions may be held due to its abstract physical formalism, have already found various applications even outside the orthodox physics domain. In this paper we introduce the concept of a quantum auction, its advantages and drawbacks. Then we describe the models that have already been put forward. A general model involves Wigner formalism and infinite dimensional Hilbert spaces - we envisage that the implementation might not be an easy task. But a restricted model advocated by the Hewlett-Packard group (Hogg et al.) seems to be much easier to implement. We focus on problems related to combinatorial auctions and technical assumptions that are made. Powerful quantum algorithms for finding solutions would extend the range of possible applications. Quantum strategies, being qubits, can be teleported but are immune from cloning - therefore extreme privacy of the agent’s activity could in principle be guaranteed. Then we point out some key problems that have to be solved before commercial use would be possible. With present technology, optical networks, single photon sources and detectors seems to be sufficient for an experimental realization in the near future.

  14. A mechanism that triggers double arcing during plasma arc cutting

    NASA Astrophysics Data System (ADS)

    Nemchinsky, Valerian

    2009-10-01

    Double arcing (DA) is a phenomenon when a transferred arc, flowing inside an electrically insulated nozzle, breaks into two separate arcs: one that connects the cathode and the nozzle and another that connects the nozzle and a work-piece. It is a commonly accepted opinion that the reason for DA is high voltage drop in the plasma inside the nozzle. However, the specific mechanism that triggers the DA development is not clear. In this paper, we propose such a mechanism. Dielectric films deposited inside the nozzle's orifice play the key role in this mechanism. These films are charged by ion current from plasma. A strong electric field is created inside the film and at the boundary of the film and clean metal of the nozzle. This gives rise to a thermo-field electron emission from the clean metal that borders the film. Emitted electrons are accelerated at the voltage drop between the nozzle and plasma. These electrons produce extra ions, which in turn move back to the film and additionally charge it. This sequence of events leads to explosive instability if the voltage drop inside the nozzle is high enough. Experiments to check the proposed mechanism are suggested.

  15. Bayesian Auctions with Friends and Foes

    NASA Astrophysics Data System (ADS)

    Chen, Po-An; Kempe, David

    We study auctions whose bidders are embedded in a social or economic network. As a result, even bidders who do not win the auction themselves might derive utility from the auction, namely, when a friend wins. On the other hand, when an enemy or competitor wins, a bidder might derive negative utility. Such spite and altruism will alter the bidding strategies. A simple and natural model for bidders’ utilities in these settings posits that the utility of a losing bidder i as a result of bidder j winning is a constant (positive or negative) fraction of bidder j’s utility.

  16. Double-peak mechanical properties of carbon-nanotube fibers.

    PubMed

    Zhao, Jingna; Zhang, Xiaohua; Di, Jiangtao; Xu, Geng; Yang, Xiaojie; Liu, Xiangyang; Yong, Zhenzhong; Chen, Minghai; Li, Qingwen

    2010-11-22

    The introduction of twist during the spinning of carbon nanotubes from their arrays (forests) has been widely applied in making ultrastrong, stiff, and lightweight nanotube fibers. Here, for the first time, an important observation of a double-peak behavior of the tensile properties, as a function of the twist angle, that is different from the single peak of traditional fibers is reported. Raman spectra show that the new peak arises from the collapse of nanotubes, showing a strong "nano" element in applying the ancient draw-and-twist technique, besides the downsizing. A qualitative continuum model is also presented to describe the collapse-induced enhancement as well as traditional fibers. Our combined experimental and theoretical studies indicate the direction of full utilization of the nano element in improving the mechanical properties of nanotube fibers. PMID:20941775

  17. Double-exchange mechanism for CrO2

    NASA Astrophysics Data System (ADS)

    Schlottmann, P.

    2003-05-01

    Band-structure calculations predict a gap of 1.5 eV in the minority-spin density of states of the half-metallic ferromagnet CrO2. The magnitude of TC, the magnons, and the activation gap in the resistivity cannot be explained with this band picture. We propose a double-exchange mechanism for two electrons per Cr site invoking strong Hund’s rule correlations and the distortion in the CrO6 octahedra, which localize one electron into the xy orbital at each Cr site, while the electrons in the xz and yz orbitals are itinerant. The effective exchange interaction naturally leads to a ferromagnetic ground state with low-energy magnon excitations and several branches of excitations separated by energy gaps from the ground state, reducing TC. Quantum fluctuations suppress the orbital long-range order, giving rise to an orbital resonant valence bond-type ground state.

  18. Auction-based distributed efficient economic operations of microgrid systems

    NASA Astrophysics Data System (ADS)

    Zou, Suli; Ma, Zhongjing; Liu, Xiangdong

    2014-12-01

    This paper studies the economic operations of the microgrid in a distributed way such that the operational schedule of each of the units, like generators, load units, storage units, etc., in a microgrid system, is implemented by autonomous agents. We apply and generalise the progressive second price (PSP) auction mechanism which was proposed by Lazar and Semret to efficiently allocate the divisible network resources. Considering the economic operation for the microgrid systems, the generators play as sellers to supply energy and the load units play as the buyers to consume energy, while a storage unit, like battery, super capacitor, etc., may transit between buyer and seller, such that it is a buyer when it charges and becomes a seller when it discharges. Furthermore in a connected mode, each individual unit competes against not only the other individual units in the microgrid but also the exogenous main grid possessing fixed electricity price and infinite trade capacity; that is to say, the auctioneer assigns the electricity among all individual units and the main grid with respect to the submitted bid strategies of all individual units in the microgrid in an economic way. Due to these distinct characteristics, the underlying auction games are distinct from those studied in the literature. We show that under mild conditions, the efficient economic operation strategy is a Nash equilibrium (NE) for the PSP auction games, and propose a distributed algorithm under which the system can converge to an NE. We also show that the performance of worst NE can be bounded with respect to the system parameters, say the energy trading price with the main grid, and based upon that, the implemented NE is unique and efficient under some conditions.

  19. Analysis of femtosecond quantum control mechanisms with colored double pulses

    SciTech Connect

    Vogt, Gerhard; Nuernberger, Patrick; Selle, Reimer; Dimler, Frank; Brixner, Tobias; Gerber, Gustav

    2006-09-15

    Fitness landscapes based on a limited number of laser pulse shape parameters can elucidate reaction pathways and can help to find the underlying control mechanism of optimal pulses determined by adaptive femtosecond quantum control. In a first experiment, we employ colored double pulses and systematically scan both the temporal subpulse separation and the relative amplitude of the two subpulses to acquire fitness landscapes. Comparison with results obtained from a closed-loop experiment demonstrates the capability of fitness landscapes for the revelation of possible control mechanisms. In a second experiment, using transient absorption spectroscopy, we investigate and compare the dependence of the excitation efficiency of the solvated dye molecule 5,5{sup '}-dichloro-11-diphenylamino-3,3{sup '}-diethyl-10,12-ethylene thiatricarbocyanine perchlorate (IR140) on selected pulse shapes in two parametrizations. The results show that very different pulse profiles can be equivalently adequate to maximize a given control objective. Fitness landscapes thus provide valuable information about different pathways along which a molecular system can be controlled with shaped laser pulses.

  20. Design Implications of Real-Time Feedback in Continuous Combinatorial Auctions: An Experimental Investigation

    ERIC Educational Resources Information Center

    Sanyal, Pallab

    2009-01-01

    Information Technology (IT) has spawned the growth of novel and innovative market mechanisms (such as online auctions) and associated businesses (such as eBay and Priceline) that were not feasible without the capabilities and reach of these modern information technologies. Previous studies on designing trading mechanisms for online markets…

  1. Auctionable fixed transmission rights for congestion management

    NASA Astrophysics Data System (ADS)

    Alomoush, Muwaffaq Irsheid

    the transaction by the ISO, take a decision to expand the existing system, or retain the original structure of the system. Also, the thesis investigates the impact of wheeling transactions on congestion management, where we present a generalized mathematical model for the Fixed Transmission Right (FTR) auction. The auction guarantees FTR availability to all participants on a non-discriminatory basis, in which system users are permitted to buy, sell and trade FTRs through an auction. When FTRs are utilized with LMPs, they increase the efficient use of the transmission system and let a transmission customer gain advantageous features such as acquiring a mechanism to offset the extra cost due to congestion charges, providing financial and operational certainty and making system users pay for the actual use of the congested paths. The thesis also highlighted FTR trading in secondary markets to self-arrange access across different paths, create long-term transmission rights and provide more commercial certainty.

  2. A Bayesian formulation for auction-based task allocation in heterogeneous multi-agent teams

    NASA Astrophysics Data System (ADS)

    Pippin, Charles E.; Christensen, Henrik

    2011-06-01

    In distributed, heterogeneous, multi-agent teams, agents may have different capabilities and types of sensors. Agents in dynamic environments will need to cooperate in real-time to perform tasks with minimal costs. Some example scenarios include dynamic allocation of UAV and UGV robot teams to possible hurricane survivor locations, search and rescue and target detection. Auction based algorithms scale well because agents generally only need to communicate bid information. In addition, the agents are able to perform their computations in parallel and can operate on local information. Furthermore, it is easy to integrate humans and other vehicle types and sensor combinations into an auction framework. However, standard auction mechanisms do not explicitly consider sensors with varying reliability. The agents sensor qualities should be explicitly accounted. Consider a scenario with multiple agents, each carrying a single sensor. The tasks in this case are to simply visit a location and detect a target. The sensors are of varying quality, with some having a higher probability of target detection. The agents themselves may have different capabilities, as well. The agents use knowledge of their environment to submit cost-based bids for performing each task and an auction is used to perform the task allocation. This paper discusses techniques for including a Bayesian formulation of target detection likelihood into this auction based framework for performing task allocation across multi-agent heterogeneous teams. Analysis and results of experiments with multiple air systems performing distributed target detection are also included.

  3. Fluid mechanics of DNA double-strand filter elution.

    PubMed Central

    Rudinger, George; Blazek, Ed Robert

    2002-01-01

    Measurement of infrequent DNA double-strand breaks (DSB) in mammalian cells is essential for the understanding of cell damage by ionizing radiation and many DNA-reactive drugs. One of the most important assays for measuring DSB in cellular DNA is filter elution. This study is an attempt to determine whether standard concepts of fluid mechanics can yield a self-consistent model of this process. Major assumptions of the analysis are reptation through a channel formed by surrounding strands, with only strand ends captured by filter pores. Both viscosity and entanglement with surrounding strands are considered to determine the resistance to this motion. One important result is that the average elution time of a strand depends not only on its length, but also on the size distribution of the surrounding strands. This model is consistent with experimental observations, such as the dependence of elution kinetics upon radiation dose, but independence from the size of the DNA sample up to a critical filter loading, and possible overlap of elution times for strands of different length. It indicates how the dependence of elution time on the flow rate could reveal the relative importance of viscous and entanglement resistance, and also predicts the consequences of using different filters. PMID:11751292

  4. Double Higgs mechanisms, supermassive stable particles and the vacuum energy

    NASA Astrophysics Data System (ADS)

    Santillán, Osvaldo P.; Gabbanelli, Luciano

    2016-07-01

    In the present work, a hidden scenario which cast a long-lived superheavy particle A0 and simultaneously an extremely light particle a with mass ma ˜ 10‑32-10‑33 eV is presented. The potential energy V (a) of the particle a models the vacuum energy density of the universe ρc ≃ 10‑47GeV4. On the other hand, the A0 particle may act as superheavy dark matter at present times and the products of its decay may be observed in high energy cosmic ray events. The hidden sector proposed here include light fermions with masses near the neutrino mass mν ˜ 10‑2 eV and superheavy ones with masses of the order of the GUT scale, interacting through a hidden SU(2)L interaction which also affects the ordinary sector. The construction of such combined scenario is nontrivial since the presence of light particles may spoil the stability of the heavy particle A0. However, double Higgs mechanisms may be helpful for overcoming this problem. In this context, the stability of the superheavy particle A0 is ensured due to chiral symmetry arguments elaborated in the text.

  5. Physical mechanism of current-free double layers

    SciTech Connect

    Chen, Francis F.

    2006-03-15

    Undriven double layers observed in plasmas expanding along magnetic fields are the result of a sheath instability connected with the Bohm criterion. Diverging magnetic field lines cause the presheath acceleration of ions, causing a potential jump resembling that of a double layer. The process stops when it runs out of energy.

  6. The value of victory: social origins of the winner's curse in common value auctions

    PubMed Central

    van den Bos, Wouter; Li, Jian; Lau, Tatiana; Maskin, Eric; Cohen, Jonathan D.; Montague, P. Read; McClure, Samuel M.

    2009-01-01

    Auctions, normally considered as devices facilitating trade, also provide a way to probe mechanisms governing one's valuation of some good or action. One of the most intriguing phenomena in auction behavior is the winner's curse — the strong tendency of participants to bid more than rational agent theory prescribes, often at a significant loss. The prevailing explanation suggests that humans have limited cognitive abilities that make estimating the correct bid difficult, if not impossible. Using a series of auction structures, we found that bidding approaches rational agent predictions when participants compete against a computer. However, the winner's curse appears when participants compete against other humans, even when cognitive demands for the correct bidding strategy are removed. These results suggest the humans assign significant future value to victories over human but not over computer opponents even though such victories may incur immediate losses, and that this valuation anomaly is the origin of apparently irrational behavior. PMID:20305741

  7. 41 CFR 102-38.95 - What is an auction?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is an auction? 102-38.95 Section 102-38.95 Public Contracts and Property Management Federal Property Management... Sales Process Competitive Sales § 102-38.95 What is an auction? An auction is a sale where the...

  8. Auctioneering Training Certificate Program 93-1001. Final Report.

    ERIC Educational Resources Information Center

    Clark, Charles H.

    A project was conducted to prepare a catalog of duties and tasks, performance objectives and guides, and instructional materials that would enable schools to develop instructional programs designed to prepare persons to enter the career of auctioneering. An occupational survey of auctioneers was conducted; a writing team of auctioneers prepared…

  9. Bidding Agents That Perpetrate Auction Fraud

    NASA Astrophysics Data System (ADS)

    Trevathan, Jarrod; McCabe, Alan; Read, Wayne

    This paper presents a software bidding agent that inserts fake bids on the seller's behalf to inflate an auction's price. This behaviour is referred to as shill bidding. Shill bidding is strictly prohibited by online auctioneers, as it defrauds unsuspecting buyers by forcing them to pay more for the item. The malicious bidding agent was constructed to aid in developing shill detection techniques. We have previously documented a simple shill bidding agent that incrementally increases the auction price until it reaches the desired profit target, or it becomes too risky to continue bidding. This paper presents an adaptive shill bidding agent which when used over a series of auctions with substitutable items, can revise its strategy based on bidding behaviour in past auctions. The adaptive agent applies a novel prediction technique referred to as the Extremum Consistency (EC) algorithm, to determine the optimal price to aspire for. The EC algorithm has successfully been used in handwritten signature verification for determining the maximum and minimum values in an input stream. The agent's ability to inflate the price has been tested in a simulated marketplace and experimental results are presented.

  10. Double exchange mechanism for CrO_2

    NASA Astrophysics Data System (ADS)

    Schlottmann, P.

    2003-03-01

    CrO2 is a half-metallic ferromagnet with a Curie temperature of about 400 K and a saturation magnetization of 2.0 μB per Cr ion. The low T magnetization follows the T^3/2 dependence expected from magnons and the resistivity has a T^2 dependence superimposed to an Arrhenius law with an activation energy of 90 K. LSDA band structure calculations predict a gap of 1.5 eV in the minority spin density of states. The magnitude of T_c, the magnons and the activation gap cannot be explained with this band picture. We propose a double exchange mechanism for two electrons per Cr site invoking strong Hund's rule correlations and the distortion in the CrO6 octahedra, which localize one electron into the xy orbital at each Cr site, while the electrons in the xz and yz orbitals are itinerant. The effective exchange interaction naturally leads to a ferromagnetic ground state with low-energy magnon excitations and several branches of excitations separated by energy gaps from the ground state, reducing T_c. A strong depolarization as a function of T is also expected. Quantum fluctuations suppress the orbital long range order, giving rise to an orbital RVB-type ground state. Work supported by DARPA through ONR under contract No. MDA972-02-1-0002. Support by NSF under grant No. DMR01-05431 and DOE under grant No. DE-FG02-98ER45797 is also acknowledged.

  11. Reciprocity in Online Markets: Empirical Studies of Auction and Barter Markets

    ERIC Educational Resources Information Center

    Ye, Shun

    2013-01-01

    My dissertation seeks to understand how reciprocity affects transaction outcomes and mechanism design in online markets. The first essay examines negative reciprocity illustrated as feedback-revoking behavior in the eBay auction market, focusing on its impact and implications for reputation system design. I utilize the biggest policy change of…

  12. Mechanisms of Strong-Field Double Ionization of Xe

    NASA Astrophysics Data System (ADS)

    Sun, Xufei; Li, Min; Ye, Difa; Xin, Guoguo; Fu, Libin; Xie, Xiguo; Deng, Yongkai; Wu, Chengyin; Liu, Jie; Gong, Qihuang; Liu, Yunquan

    2014-09-01

    We perform a fully differential measurement on strong-field double ionization of Xe by 25 fs, 790 nm laser pulses in intensity region (0.4-3)×1014 W/cm2. We observe that the two-dimensional correlation momentum spectra along the laser polarization direction show a nonstructured distribution for double ionization of Xe when decreasing the laser intensity from 3×1014 to 4×1013 W /cm2. The electron correlation behavior is remarkably different with the low-Z rare gases, i.e., He, Ne, and Ar. We find that the electron energy cutoffs increase from 2.9Up to 7.8Up when decreasing the laser intensities from the sequential double ionization to the nonsequential double ionization regime. The experimental observation indicates that multiple rescatterings play an important role for the generation of high energy photoelectrons. We have further studied the shielding effect on the strong-field double ionization of high-Z atoms.

  13. China’s Land Market Auctions: Evidence of Corruption?

    PubMed Central

    Cai, Hongbin; Henderson, J. Vernon; Zhang, Qinghua

    2013-01-01

    This paper studies the urban land market in China in 2003—2007. In China, all urban land is owned by the state. Leasehold use rights for land for (re)development are sold by city governments and are a key source of city revenue. Leasehold sales are viewed as a major venue for corruption, prompting a number of reforms over the years. Reforms now require all leasehold rights be sold at public auction. There are two main types of auction: regular English auction and an unusual type which we call a “two stage auction”. The latter type of auction seems more subject to corruption, and to side deals between potential bidders and the auctioneer. Absent corruption, theory suggests that two stage auctions would most likely maximize sales revenue for properties which are likely to have relatively few bidders, or are “cold”, which would suggest negative selection on property unobservables into such auctions. However, if such auctions are more corruptible, that could involve positive selection as city officials divert hotter properties to a more corruptible auction form. The paper finds that, overall, sales prices are lower for two stage auctions, and there is strong evidence of positive selection. The price difference is explained primarily by the fact that two stage auctions typically have just one bidder, or no competition despite the vibrant land market in Chinese cities. PMID:25506125

  14. 47 CFR 1.2208 - Public notice of auction completion and auction results.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PROCEDURE Grants by Random Selection Competitive Bidding Proceedings Broadcast Television Spectrum Reverse... broadcast television spectrum incentive auction conducted under section 6403 of the Spectrum Act, public... indicate that the reassignments of television channels and reallocations of broadcast television...

  15. Deformation effect simulation and optimization for double front axle steering mechanism

    NASA Astrophysics Data System (ADS)

    Wu, Jungang; Zhang, Siqin; Yang, Qinglong

    2013-03-01

    This paper research on tire wear problem of heavy vehicles with Double Front Axle Steering Mechanism from the flexible effect of Steering Mechanism, and proposes a structural optimization method which use both traditional static structural theory and dynamic structure theory - Equivalent Static Load (ESL) method to optimize key parts. The good simulated and test results show this method has high engineering practice and reference value for tire wear problem of Double Front Axle Steering Mechanism design.

  16. Shell model nuclear matrix elements for competing mechanisms contributing to double beta decay

    SciTech Connect

    Horoi, Mihai

    2013-12-30

    Recent progress in the shell model approach to the nuclear matrix elements for the double beta decay process are presented. This includes nuclear matrix elements for competing mechanisms to neutrionless double beta decay, a comparison between closure and non-closure approximation for {sup 48}Ca, and an updated shell model analysis of nuclear matrix elements for the double beta decay of {sup 136}Xe.

  17. 43 CFR 2546.4 - Public auctions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Public auctions. 2546.4 Section 2546.4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) COLOR-OF-TITLE AND OMITTED LANDS Snake...

  18. 43 CFR 2546.4 - Public auctions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Public auctions. 2546.4 Section 2546.4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) COLOR-OF-TITLE AND OMITTED LANDS Snake...

  19. 43 CFR 2546.4 - Public auctions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Public auctions. 2546.4 Section 2546.4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) COLOR-OF-TITLE AND OMITTED LANDS Snake...

  20. 43 CFR 2546.4 - Public auctions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Public auctions. 2546.4 Section 2546.4 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) COLOR-OF-TITLE AND OMITTED LANDS Snake...

  1. 7 CFR 1955.148 - Auction sales.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... This section provides guidance on the sale of all inventory property by auction, except FSA real... property, will determine and document the minimum sale price acceptable. In determining a minimum sale... on sales of program and property. For NP property, credit may be offered to facilitate the...

  2. 19 CFR 127.34 - Auctioneer's commissions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Auctioneer's commissions. 127.34 Section 127.34 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY GENERAL ORDER, UNCLAIMED, AND ABANDONED MERCHANDISE Proceeds of Sale § 127.34...

  3. Cryptographic Combinatorial Clock-Proxy Auctions

    NASA Astrophysics Data System (ADS)

    Parkes, David C.; Rabin, Michael O.; Thorpe, Christopher

    We present a cryptographic protocol for conducting efficient, provably correct and secrecy-preserving combinatorial clock-proxy auctions. The “clock phase” functions as a trusted auction despite price discovery: bidders submit encrypted bids, and prove for themselves that they meet activity rules, and can compute total demand and thus verify price increases without revealing any information about individual demands. In the sealed-bid “proxy phase”, all bids are revealed the auctioneer via time-lapse cryptography and a branch-and-bound algorithm is used to solve the winner-determination problem. Homomorphic encryption is used to prove the correctness of the solution, and establishes the correctness of the solution to any interested party. Still an NP-hard optimization problem, the use of homomorphic encryption imposes additional computational time on winner-determination that is linear in the size of the branch-and-bound search tree, and thus roughly linear in the original (search-based) computational time. The result is a solution that avoids, in the usual case, the exponential complexity of previous cryptographically-secure combinatorial auctions.

  4. Books at Auction: The Art of Deaccessioning.

    ERIC Educational Resources Information Center

    Model, Peter

    1981-01-01

    Lack of space and budget cuts force many libraries to weed out books and to be selective in accepting collection bequests. The approach for deciding which books to weed out and whether to dispose of these books through dealers or auctions are decisions private clubs and many libraries must make. (RBF)

  5. 7 CFR 1955.131 - Auctioneers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Auctioneers. 1955.131 Section 1955.131 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED)...

  6. The Double-Well Potential in Quantum Mechanics: A Simple, Numerically Exact Formulation

    ERIC Educational Resources Information Center

    Jelic, V.; Marsiglio, F.

    2012-01-01

    The double-well potential is arguably one of the most important potentials in quantum mechanics, because the solution contains the notion of a state as a linear superposition of "classical" states, a concept which has become very important in quantum information theory. It is therefore desirable to have solutions to simple double-well potentials…

  7. Elucidating the mechanisms of double ionization using intense half-cycle, single-cycle, and double half-cycle pulses

    SciTech Connect

    Kamta, G. Lagmago; Starace, Anthony F.

    2003-10-01

    We investigate the interaction of a two-active electron system (Li{sup -}) with intense single-cycle and double half-cycle pulses. The 'intensity' and 'frequency' considered correspond to the 'multiphoton above-barrier regime'. For the single-cycle pulse (SCP), the electric field changes sign once, allowing electron wave packets created during the first half cycle to recollide with the parent ion when driven back by the field. For the double half-cycle pulse (DHP), however, the electric field does not change sign, and electron wave packets created during the first half cycle are not driven back to the parent ion. We find that both single and double ionization are significantly larger for the SCP than for the DHP, thereby elucidating the role of the rescattering mechanism. On the other hand, doubly ionized electrons produced by a half-cycle pulse and a DHP are found to have angular distributions in which one electron is ejected in the direction of the pulse field, and the other in the opposite direction. This clear signature of electron correlations suggests that 'shake-off', 'knockout', and, possibly, 'multiphoton-sharing' processes are alternative contributing mechanisms for double ionization in this regime.

  8. On Revenue-Optimal Dynamic Auctions for Bidders with Interdependent Values

    NASA Astrophysics Data System (ADS)

    Constantin, Florin; Parkes, David C.

    In a dynamic market, being able to update one's value based on information available to other bidders currently in the market can be critical to having profitable transactions. This is nicely captured by the model of interdependent values (IDV): a bidder's value can explicitly depend on the private information of other bidders. In this paper we present preliminary results about the revenue properties of dynamic auctions for IDV bidders. We adopt a computational approach to design single-item revenue-optimal dynamic auctions with known arrivals and departures but (private) signals that arrive online. In leveraging a characterization of truthful auctions, we present a mixed-integer programming formulation of the design problem. Although a discretization is imposed on bidder signals the solution is a mechanism applicable to continuous signals. The formulation size grows exponentially in the dependence of bidders' values on other bidders' signals. We highlight general properties of revenue-optimal dynamic auctions in a simple parametrized example and study the sensitivity of prices and revenue to model parameters.

  9. Auction design and the market for sulfur dioxide emissions

    SciTech Connect

    Joskow, P.L.; Schmalensee, R.; Bailey, E.M.

    1997-12-31

    Title IV of the Clean Air Act Amendments of 1990 created a market for electric utility emissions of sulfur dioxide (SO{sub 2}). Recent papers have argued that flaws in the design of the auctions that are part of this market have adversely affected its performance. These papers incorrectly assume that trade can only occur at auctions, however. Our empirical analysis of the SO{sub 2} emissions market shows that the auctions have become a small part of a relatively efficient market and that the auction design problems that have attracted the most attention have had no effect on actual market prices.

  10. Auctions vs negotiations: a study of price differentials.

    PubMed

    Kjerstad, Egil

    2005-12-01

    Recent contributions in auction and bargaining theory suggest that a procurer should place more faith in the power of competition among alternative suppliers than in his or her own negotiating skill. Based on data from 216 contracts between procurers and suppliers of medical and surgical articles, we test whether auctions and bargaining result in significantly different prices. The main results are that auctions give 'thicker' markets compared with negotiations, as expected, but that auctions do not result in significantly lower prices compared with negotiations. PMID:15945037

  11. ``Quasi-complete'' mechanical model for a double torsion pendulum

    NASA Astrophysics Data System (ADS)

    De Marchi, Fabrizio; Pucacco, Giuseppe; Bassan, Massimo; De Rosa, Rosario; Di Fiore, Luciano; Garufi, Fabio; Grado, Aniello; Marconi, Lorenzo; Stanga, Ruggero; Stolzi, Francesco; Visco, Massimo

    2013-06-01

    We present a dynamical model for the double torsion pendulum nicknamed “PETER,” where one torsion pendulum hangs in cascade, but off axis, from the other. The dynamics of interest in these devices lies around the torsional resonance, that is at very low frequencies (mHz). However, we find that, in order to properly describe the forced motion of the pendulums, also other modes must be considered, namely swinging and bouncing oscillations of the two suspended masses, that resonate at higher frequencies (Hz). Although the system has obviously 6+6 degrees of freedom, we find that 8 are sufficient for an accurate description of the observed motion. This model produces reliable estimates of the response to generic external disturbances and actuating forces or torques. In particular, we compute the effect of seismic floor motion (“tilt” noise) on the low frequency part of the signal spectra and show that it properly accounts for most of the measured low frequency noise.

  12. End Resection at Double-Strand Breaks: Mechanism and Regulation

    PubMed Central

    Symington, Lorraine S.

    2014-01-01

    RecA/Rad51 catalyzed pairing of homologous DNA strands, initiated by polymerization of the recombinase on single-stranded DNA (ssDNA), is a universal feature of homologous recombination (HR). Generation of ssDNA from a double-strand break (DSB) requires nucleolytic degradation of the 5′-terminated strands to generate 3′-ssDNA tails, a process referred to as 5′–3′ end resection. The RecBCD helicase–nuclease complex is the main end-processing machine in Gram-negative bacteria. Mre11-Rad50 and Mre11-Rad50-Xrs2/Nbs1 can play a direct role in end resection in archaea and eukaryota, respectively, by removing end-blocking lesions and act indirectly by recruiting the helicases and nucleases responsible for extensive resection. In eukaryotic cells, the initiation of end resection has emerged as a critical regulatory step to differentiate between homology-dependent and end-joining repair of DSBs. PMID:25085909

  13. Non-double-couple earthquake mechanisms at the Geysers geothermal area, California

    USGS Publications Warehouse

    Ross, A.; Foulger, G.R.; Julian, B.R.

    1996-01-01

    Inverting P- and S-wave polarities and P:SH amplitude ratios using linear programming methods suggests that about 20% of earthquakes at The Geysers geothermal area have significantly non-double-couple focal mechanisms, with explosive volumetric components as large as 33% of the seismic moment. This conclusion contrasts with those of earlier studies, which interpreted data in terms of double couples. The non-double-couple mechanisms are consistent with combined shear and tensile faulting, possibly caused by industrial water injection. Implosive mechanisms, which might be expected because of rapid steam withdrawal, have not been found. Significant compensated-linear-vector-dipole (CLVD) components in some mechanisms may indicate rapid fluid flow accompanying crack opening. Copyright 1996 by the American Geophysical Union.

  14. Health Auctions: a Valuation Experiment (HAVE) study protocol

    PubMed Central

    Kularatna, Sanjeewa; Petrie, Dennis; Scuffham, Paul A; Byrnes, Joshua

    2016-01-01

    Introduction Quality-adjusted life years are derived using health state utility weights which adjust for the relative value of living in each health state compared with living in perfect health. Various techniques are used to estimate health state utility weights including time-trade-off and standard gamble. These methods have exhibited limitations in terms of complexity, validity and reliability. A new composite approach using experimental auctions to value health states is introduced in this protocol. Methods and analysis A pilot study will test the feasibility and validity of using experimental auctions to value health states in monetary terms. A convenient sample (n=150) from a population of university staff and students will be invited to participate in 30 auction sets with a group of 5 people in each set. The 9 health states auctioned in each auction set will come from the commonly used EQ-5D-3L instrument. At most participants purchase 2 health states, and the participant who acquires the 2 ‘best’ health states on average will keep the amount of money they do not spend in acquiring those health states. The value (highest bid and average bid) of each of the 24 health states will be compared across auctions to test for reliability across auction groups and across auctioneers. A test retest will be conducted for 10% of the sample to assess reliability of responses for health states auctions. Feasibility of conducting experimental auctions to value health states will also be examined. The validity of estimated health states values will be compared with published utility estimates from other methods. This pilot study will explore the feasibility, reliability and validity in using experimental auction for valuing health states. Ethics and dissemination Ethical clearance was obtained from Griffith University ethics committee. The results will be disseminated in peer-reviewed journals and major international conferences. PMID:27056589

  15. A Trustworthy Internet Auction Model with Verifiable Fairness.

    ERIC Educational Resources Information Center

    Liao, Gen-Yih; Hwang, Jing-Jang

    2001-01-01

    Describes an Internet auction model achieving verifiable fairness, a requirement aimed at enhancing the trust of bidders in auctioneers. Analysis results demonstrate that the proposed model satisfies various requirements regarding fairness and privacy. Moreover, in the proposed model, the losing bids remain sealed. (Author/AEF)

  16. A Classroom Auction with Externalities: Applied to Mergers and Acquisitions

    ERIC Educational Resources Information Center

    Meister, J. Patrick; Anderson, Kyle J.

    2007-01-01

    The authors describe an in-class exercise in which students participate in an auction to buy US Airways. The exercise is based on events of late 1995, in which neither United nor American Airlines decided to bid for US Airways. Two teams of students participate in an English auction. Students learn that the equilibrium of the sequential game is…

  17. 75 FR 8070 - Closed Auction of Broadcast Construction Permits Scheduled for July 20, 2010; Auction 88...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... announces the auction of certain broadcast FM, AM, and FM Translator construction permits scheduled to... certain broadcast FM, AM, and FM Translator construction permits and sought comment on the procedures to... resolve mutual exclusivity between applications for new AM stations on 640 kHz and 1230 kHz in the...

  18. Detecting Fraud in Internet Auction Systems

    NASA Astrophysics Data System (ADS)

    Peng, Yanlin; Zhang, Linfeng; Guan, Yong

    Fraud compromises the thriving Internet auction market. Studies have shown that fraudsters often manipulate their reputations through sophisticated collusions with accomplices, enabling them to defeat the reputation-based feedback systems that are used to combat fraud. This paper presents an algorithm that can identify colluding fraudsters in real time. Experiments with eBay transaction data show that the algorithm has low false negative and false positive rates. Furthermore, the algorithm can identify fraudsters who are innocent at the time of the data collection, but engage in fraudulent transactions soon after they accumulate good feedback ratings.

  19. Physical mechanisms of active control of sound transmission through rib stiffened double-panel structure

    NASA Astrophysics Data System (ADS)

    Ma, Xiyue; Chen, Kean; Ding, Shaohu; Yu, Haoxin

    2016-06-01

    This paper presents an analytical investigation on physical mechanisms of actively controlling sound transmission through a rib stiffened double-panel structure using point source in the cavity. The combined modal expansion and vibro-acoustic coupling methods are applied to establish the theoretical model of such active structure. Under the condition of minimizing radiated power of the radiating ribbed plate, the physical mechanisms are interpreted in detail from the point of view of modal couplings similar as that used in existed literatures. Results obtained demonstrate that the rule of sound energy transmission and the physical mechanisms for the rib stiffened double-panel structure are all changed, and affected by the coupling effects of the rib when compared with the analytical results obtained for unribbed double-panel case. By taking the coupling effects of the rib into considerations, the cavity modal suppression and rearrangement mechanisms obtained in existed investigations are modified and supplemented for the ribbed plate case, which gives a clear interpretation for the physical nature involved in the active rib stiffened double-panel structure.

  20. COMPARISON OF RELATIVE EMISSIONS FROM DOUBLE MECHANICAL PUMP SEALS TO OTHER TYPES OF PUMP SHAFT SEALS

    EPA Science Inventory

    The report gives results of a comparison of pump seal data from nine petroleum refineries, to evaluate emissions from double mechanical pump seals versus those from other types of pump shaft seals. Light- and heavy-liquid service seals were compared separately. Non-methane leak r...

  1. Using Priced Options to Solve the Exposure Problem in Sequential Auctions

    NASA Astrophysics Data System (ADS)

    Mous, Lonneke; Robu, Valentin; La Poutré, Han

    This paper studies the benefits of using priced options for solving the exposure problem that bidders with valuation synergies face when participating in multiple, sequential auctions. We consider a model in which complementary-valued items are auctioned sequentially by different sellers, who have the choice of either selling their good directly or through a priced option, after fixing its exercise price. We analyze this model from a decision-theoretic perspective and we show, for a setting where the competition is formed by local bidders, that using options can increase the expected profit for both buyers and sellers. Furthermore, we derive the equations that provide minimum and maximum bounds between which a synergy buyer's bids should fall in order for both sides to have an incentive to use the options mechanism. Next, we perform an experimental analysis of a market in which multiple synergy bidders are active simultaneously.

  2. Congestion pricing by priority auction

    NASA Astrophysics Data System (ADS)

    Zhang, Guanxiang; He, Jianhua; Ma, Yajie; Cheng, Wenqing; Yang, Zongkai

    2005-02-01

    This paper analyzes a communication network facing users with a continuous distribution of delay cost per unit time. Priority queueing is often used as a way to provide differential services for users with different delay sensitivities. Delay is a key dimension of network service quality, so priority is a valuable resource which is limited and should to be optimally allocated. We investigate the allocation of priority in queues via a simple bidding mechanism. In our mechanism, arriving users can decide not to enter the network at all or submit an announced delay sensitive value. User entering the network obtains priority over all users who make lower bids, and is charged by a payment function which is designed following an exclusion compensation principle. The payment function is proved to be incentive compatible, so the equilibrium bidding behavior leads to the implementation of "cμ-rule". Social warfare or revenue maximizing by appropriately setting the reserve payment is also analyzed.

  3. Nonlinearity from quantum mechanics: Dynamically unstable Bose-Einstein condensate in a double-well trap

    SciTech Connect

    Javanainen, Juha

    2010-05-15

    We study theoretically an atomic Bose-Einstein condensate in a double-well trap, both quantum-mechanically and classically, under conditions such that in the classical model an unstable equilibrium dissolves into large-scale oscillations of the atoms between the potential wells. Quantum mechanics alone does not exhibit such nonlinear dynamics, but measurements of the atom numbers in the potential wells may nevertheless cause the condensate to behave essentially classically.

  4. Rationality, Irrationality and Escalating Behavior in Lowest Unique Bid Auctions

    PubMed Central

    Radicchi, Filippo; Baronchelli, Andrea; Amaral, Luís A. N.

    2012-01-01

    Information technology has revolutionized the traditional structure of markets. The removal of geographical and time constraints has fostered the growth of online auction markets, which now include millions of economic agents worldwide and annual transaction volumes in the billions of dollars. Here, we analyze bid histories of a little studied type of online auctions – lowest unique bid auctions. Similarly to what has been reported for foraging animals searching for scarce food, we find that agents adopt Lévy flight search strategies in their exploration of “bid space”. The Lévy regime, which is characterized by a power-law decaying probability distribution of step lengths, holds over nearly three orders of magnitude. We develop a quantitative model for lowest unique bid online auctions that reveals that agents use nearly optimal bidding strategies. However, agents participating in these auctions do not optimize their financial gain. Indeed, as long as there are many auction participants, a rational profit optimizing agent would choose not to participate in these auction markets. PMID:22279553

  5. Smarter than Others? Conjectures in Lowest Unique Bid Auctions

    PubMed Central

    Hu, Rui; Chen, Qinghua

    2015-01-01

    Research concerning various types of auctions, such as English auctions, Dutch auctions, highest-price sealed-bid auctions, and second-price sealed-bid auctions, is always a topic of considerable interest in interdisciplinary fields. The type of auction, known as a lowest unique bid auction (LUBA), has also attracted significant attention. Various models have been proposed, but they often fail to explain satisfactorily the real bid-distribution characteristics. This paper discusses LUBA bid-distribution characteristics, including the inverted-J shape and the exponential decrease in the upper region. The authors note that this type of distribution, which initially increases and later decreases, cannot be derived from the symmetric Nash equilibrium framework based on perfect information that has previously been used. A novel optimization model based on non-perfect information is presented. The kernel of this model is the premise that agents make decisions to achieve maximum profit based on imaginary information or assumptions regarding the behavior of others. PMID:25849631

  6. Competition strength influences individual preferences in an auction game

    PubMed Central

    Toelch, Ulf; Jubera-Garcia, Esperanza; Kurth-Nelson, Zeb; Dolan, Raymond J.

    2014-01-01

    Competitive interactions between individuals are ubiquitous in human societies. Auctions represent an institutionalized context for these interactions, a context where individuals frequently make non-optimal decisions. In particular, competition in auctions can lead to overbidding, resulting in the so-called winner’s curse, often explained by invoking emotional arousal. In this study, we investigated an alternative possibility, namely that competitors’ bids are construed as a source of information about the good’s common value thereby influencing an individuals’ private value estimate. We tested this hypothesis by asking participants to bid in a repeated all-pay auction game for five different real items. Crucially, participants had to rank the auction items for their preference before and after the experiment. We observed a clear relation between auction dynamics and preference change. We found that low competition reduced preference while high competition increased preference. Our findings support a view that competitors’ bids in auction games are perceived as valid social signal for the common value of an item. We suggest that this influence of social information constitutes a major cause for the frequently observed deviations from optimality in auctions. PMID:25168161

  7. The communications spectrum: Frequency allocations and auctions

    NASA Astrophysics Data System (ADS)

    Pritchard, Wilbur

    1997-01-01

    Demands on the communications spectrum have increased sharply because of the growth in radio communication services, the large bandwidths now required, and the rapid increases in world population. The problem will be exacerbated by the requirements of high definition television and the enormous amounts of information that will be transmitted by radio. The electromagnetic spectrum is a finite natural resource of great value used for emergency communications and military operations as well as for commercial purposes. Both government and the marketplace have proper roles in the allocation of its resources. There are no viable alternatives to international organizations such as the International Telecommunication Union or to agencies such as the Federal Communications Commission for the regulation of radio communication and the assignment of spectrum to essential public services. Although government auctions of spectrum are justifiable where there is no way to distinguish among commercial entities seeking to use the same bands for similar services, the practice is inherently inequitable and discourages development of new uses for the spectrum by removing investment protection. Recommended alternatives to auctions are: (1) lotteries, which keep assets and proceeds in the economy; and (2) ongoing charges for current as well as new users of the spectrum.

  8. Nonsequential Two-Photon Double Ionization of Atoms: Identifying the Mechanism

    NASA Astrophysics Data System (ADS)

    Førre, Morten; Selstø, Sølve; Nepstad, Raymond

    2010-10-01

    We develop an approximate model for the process of direct (nonsequential) two-photon double ionization of atoms. Employing the model, we calculate (generalized) total cross sections as well as energy-resolved differential cross sections of helium for photon energies ranging from 39 to 54 eV. A comparison with results of ab initio calculations reveals that the agreement is at a quantitative level. We thus demonstrate that this complex ionization process can be described by the simple model, providing insight into the underlying physical mechanism. Finally, we use the model to calculate generalized cross sections for the two-photon double ionization of neon in the nonsequential regime.

  9. Kinetics and Mechanism of the Reaction of Ozone with Double Bonds

    NASA Astrophysics Data System (ADS)

    Razumovskii, S. D.; Zaikov, Gennadii E.

    1980-12-01

    Analysis of the results of recent studies has shown that the reaction of ozone with the double bonds of organic compounds apparently takes place not by a synchronous addition mechanism but through a reversible stage involving the formation of an intermediate complex of ozone with the double bond. The subsequent stages of the reaction involve the formation of a primary ozonide, its decomposition into two fragments, their combination, and a number of other transformations. The properties of the intermediate products, the relationship between the structure of the original alkenes and their reactivity towards ozone, the influence of the nature of the solvent on the direction and rate of the reaction, and the practical application of the reaction of ozone with double bonds in research and chemical technology have been examined. The bibliography contains 205 references.

  10. Double Switching of Two Rings in Palindromic [3]Pseudorotaxanes: Cooperativity and Mechanism of Motion.

    PubMed

    Benson, Christopher R; Share, Andrew I; Marzo, Matthew G; Flood, Amar H

    2016-04-18

    The existence of two rings in [3]pseudorotaxanes presents opportunities for those rings to undergo double switching and cooperative mechanical coupling. To investigate this capability, we identified a new strategy for bringing two rings into contact with each other and conducted mechanistic studies to reveal their kinetic cooperativity. A redox-active tetrazine ligand bearing two binding sites was selected to allow for two mobile copper(I) macrocycle ring moieties to come together. To realize this switching modality, ligands were screened against their ability to serve as stations on which the rings are initially parked, ultimately identifying 5,5'-dimethyl-2,2'-bipyridine. The kinetics of switching a macrocycle in a single-site [2]pseudorotaxane between bipyridine and single-site tetrazine stations were examined using electrochemistry. The forward movement was rate-limited by the bimolecular reaction between reduced tetrazine and bipyridine [2]pseudorotaxane. Two bipyridines were then used with a double-site tetrazine to verify double switching of two rings. Our results indicated stepwise movements, with the first ring moving 4 times more frequently (faster) than the second. While this behavior is indicative of anticooperative kinetics, positive thermodynamic cooperativity sets the two rings in motion even though just one tetrazine is reduced with one electron. Double switching in this [3]pseudorotaxane uniquely demonstrates how a series of independent thermodynamic states and kinetic paths govern an apparently simple mechanical motion. PMID:27050829

  11. 6. East rear, cattle auction arena below in background, Omaha ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. East rear, cattle auction arena below in background, Omaha livestock market offices above. View to west. - South Omaha Union Stock Yards, Stock Yards Autopark, 2900 "O" Plaza, Omaha, Douglas County, NE

  12. Auction fever: exploring informational social influences on bidder choices.

    PubMed

    Chen, Yi-Fen

    2011-01-01

    Previous investigations of herd behavior have identified the importance of informational social influences in consumer decision making. This research presents three studies examining herd behavior in online auctions. The three studies addressed the influence on bidder online choices of herd cues frequently found in online auctions, including bid number, feedback ratings, and number of questions and answers. This research also investigated the effect of different levels of herd cues on bidder online choices under high and low brand awareness in online auctions. The experimental results demonstrated that bidders use online herd cues when making decisions in online auctions. Additionally, different levels of herd cues influence bidder online choices in both high and low brand awareness product situations. PMID:21192763

  13. Disentangling effects of mechanisms that could contribute to the neutrinoless double beta decay

    NASA Astrophysics Data System (ADS)

    Horoi, Mihai; Neacsu, Andrei

    2015-10-01

    Neutrinoless double-beta decay, if observed, would signal physics beyond the Standard Model that could be discovered at energies significantly lower than those at which the relevant degrees of freedom could be excited. Therefore, it could be challenging to further use the neutrinoless double-beta decay observations to distinguish between many beyond Standard Model competing mechanisms to this process. Accurate nuclear structure calculation of the nuclear matrix elements necessary to analyze the decay rates could be helpful to narrow down the list of competing mechanisms, and to better identify the more exotic properties of the neutrinos. We will present information that one can get from the angular and energy distribution of the emitted electron assuming that the right-handed currents exist. Support from U.S. NSF Grant PHY-1404442 and DOE Grant DE-SC0008529 is acknowledged.

  14. Analysis of mechanisms that could contribute to neutrinoless double-beta decay

    NASA Astrophysics Data System (ADS)

    Horoi, Mihai; Neacsu, Andrei

    2016-06-01

    Neutrinoless double-beta decay is a beyond the Standard Model process that would indicate that neutrinos are Majorana fermions, and the lepton number is not conserved. It could be interesting to use the neutrinoless double-beta decay observations to distinguish between several beyond Standard Model mechanisms that could contribute to this process. Accurate nuclear structure calculations of the nuclear matrix elements necessary to analyze the decay rates could be helpful to narrow down the list of contributing mechanisms. We investigate the information one can get from the angular and energy distribution of the emitted electrons and from the half-lives of several isotopes, assuming that the right-handed currents exist. For the analysis of these distributions, we calculate the necessary nuclear matrix elements using shell model techniques, and we explicitly consider interference terms.

  15. Mechanical reliability of double clad fibers in typical fiber laser deployment conditions

    NASA Astrophysics Data System (ADS)

    Walorny, Michael; Abramczyk, Jaroslaw; Jacobson, Nick; Tankala, Kanishka

    2016-03-01

    With the rapid acceptance of fiber lasers and amplifiers for various materials processing and defense applications the long term optical and mechanical reliability of the fiber laser, and therefore the components that make up the laser, is of significant interest to the industrial and defense communities. The double clad fiber used in a fiber laser is a key component whose lifetime in typical deployment conditions needs to be understood. The optical reliability of double clad fiber has recently been studied and a predictive model of fiber lifetime has been published. In contrast, a rigorous model for the mechanical reliability of the fiber and an analysis of the variables affecting the lifetime of the fiber in typical deployment conditions has not been studied. This paper uses the COST-218 model which is widely used for analyzing the mechanical lifetime of fiber used in the telecom industry. The factors affecting lifetime are analyzed to make the reader aware of the design choices a laser manufacturer can make, and the information they must seek from fiber suppliers, to ensure excellent lifetime for double clad fiber and consequently for the fiber laser. It is shown that the fiber's stress corrosion susceptibility, its proof strength, the coil diameter and the length of fiber coiled to achieve good beam quality all have important implications on fiber lifetime.

  16. [Arc spectrum diagnostic and heat coupling mechanism analysis of double wire pulsed MIG welding].

    PubMed

    Liu, Yong-qiang; Li, Huan; Yang, Li-jun; Zheng, Kai; Gao, Ying

    2015-01-01

    A double wire pulsed MIG welding test system was built in the present paper, in order to analyze the heat-coupling mechanism of double wire pulsed MIG welding, and study are temperature field. Spectroscopic technique was used in diagnostic analysis of the are, plasma radiation was collected by using hollow probe method to obtain the arc plasma optical signal The electron temperature of double wire pulsed MIG welding arc plasma was calculated by using Boltzmann diagram method, the electron temperature distribution was obtained, a comprehensive analysis of the arc was conducted combined with the high speed camera technology and acquisition means of electricity signal. The innovation of this paper is the combination of high-speed camera image information of are and optical signal of arc plasma to analyze the coupling mechanism for dual arc, and a more intuitive analysis for are temperature field was conducted. The test results showed that a push-pull output was achieved and droplet transfer mode was a drop in a pulse in the welding process; Two arcs attracted each other under the action of a magnetic field, and shifted to the center of the arc in welding process, so a new heat center was formed at the geometric center of the double arc, and flowing up phenomenon occurred on the arc; Dual arc electronic temperature showed an inverted V-shaped distribution overall, and at the geometric center of the double arc, the arc electron temperature at 3 mm off the workpiece surface was the highest, which was 16,887.66 K, about 4,900 K higher than the lowest temperature 11,963.63 K. PMID:25993809

  17. Tilting double-prism scanner driven by cam-based mechanism.

    PubMed

    Li, Anhu; Yi, Wanli; Sun, Wansong; Liu, Liren

    2015-06-20

    A pair of orthogonal tilting prisms has been explored in our previous work to perform the orientation and position tracking function with tracking accuracy better than submicroradian order. Crucial to the function implementation, however, is the real-time nonlinear control of the tilting angles of double prisms for tracking a given target trajectory. In previous papers [Proc. SPIE5892, 1-5 (2005).PSISDG0277-786X; Appl. Opt.45, 8063 (2006).PSISDG0277-786X; Proc. SPIE6709, 41 (2007).PSISDG0277-786X; Appl. Opt.51, 356 (2011).10.1364/AO.51.000356APOPAI1559-128X; Appl. Opt.53, 3712 (2014).10.1364/AO.53.003712APOPAI1559-128X], a new driving method by a cam-based mechanism, which can transfer the control problem to the design of corresponding cam configuration, is investigated. The design process of a cam-based mechanism is explained from the mapping relation between the tilting angles of a prism and the configuration curve of a corresponding cam. Based on the designed cam-based mechanism, a tracking error less than 0.375% is depicted between the tracking trajectory and the original one. Moreover, the dynamic characteristic of the tracking mechanism is discussed in detail as well as the impacts of different tilting speeds on the tracking trajectory. The proposed tracking mechanism of a tilting double-prism scanner can create a new avenue for passively tracking a given target. PMID:26193031

  18. A novel flexure-based microgripper with double amplification mechanisms for micro/nano manipulation

    NASA Astrophysics Data System (ADS)

    Sun, Xiantao; Chen, Weihai; Tian, Yanling; Fatikow, Sergej; Zhou, Rui; Zhang, Jianbin; Mikczinski, Manuel

    2013-08-01

    This paper describes the design, modeling, and testing of a novel flexure-based microgripper for a large jaw displacement with high resolution. Such a microgripper is indispensable in micro/nano manipulation. In achieving a large jaw displacement, double amplification mechanisms, namely, Scott-Russell mechanism and leverage mechanism arranged in series, are utilized to overcome the limited output of microgrippers driven by piezoelectric actuators. The mechanical performance of the microgripper is analyzed using the pseudo rigid body model approach. Finite element analysis is conducted to evaluate the performance and validate the established models for further optimum design of the microgripper. The prototype of the developed microgripper is fabricated, with which experimental tests are carried out. The experimental results show that the developed microgripper is capable of handling various sized micro-objects with a maximum jaw displacement of 134 μm and a high amplification ratio of 15.5.

  19. Mechanical and microstructural characterization of single and double pass Aluminum AA6061 friction stir weld joints

    NASA Astrophysics Data System (ADS)

    Othman, N. H.; Shah, L. H.; Ishak, M.

    2015-12-01

    This study focuses on the effect of single pass (SP), double sided pass (DSP) and normal double pass (NDP) method on friction stir welding of aluminum AA6061. Two pieces of AA6061 alloy with thickness of 6 mm were friction stir welded by using conventional milling machine. The rotational speeds that were used in this study were 800 rpm, 1000 rpm and 1200 rpm, respectively. The welding speed is fixed to 100 mm/min. Microstructure observation of welded area was studied by using optical microscope. Tensile test and Vickers hardness test were used to evaluate the mechanical properties of this specimen. Mechanical property analysis results indicate that at low rotational speeds, defects such as surface lack of fill and tunneling in the welded area can be observed. Vickers hardness of specimens however did not vary much when rotational speed is varied. Welded specimens using single pass method shows higher tensile strength and hardness value compared to both double pass methods up to 180.61 MPa. Moreover, DSP showed better tensile test and hardness test compared to NDP method. The optimum parameters were found to be single pass method with 1200 rpm of rotational speed. Therefore economically sound to only perform SP method to obtain maximum tensile strength for AA6061 FSW with thickness of 6 mm.

  20. Photoacoustic Evaluation of the Mechanical Properties of Aluminum / Silicon Nitride Double-Layer Thin Films

    NASA Astrophysics Data System (ADS)

    Zhang, Feifei; Krishnaswamy, Sridhar; Lilley, Carmen M.

    2006-03-01

    In this paper, we compare two photoacoustic techniques to characterize the mechanical parameters of edge-supported aluminum and silicon nitride double-layer thin films. In a first set of experiments, a femtosecond transient pump-probe technique is used to investigate the Young's moduli of the aluminum and silicon nitride layers by launching ultra-high frequency bulk acoustic waves in the films. In a second set of experiments, dispersion curves of the A0 mode of the Lamb waves that propagate along the unsupported films are measured using a broadband photoacoustic guided-wave method. The residual stresses and flexural rigidities for the same set of double-layer membranes are determined from these dispersion curves. Comparisons of the results obtained by the two photoacoustic techniques are made.

  1. Competition in decentralized electricity markets: Three papers on electricity auctions

    NASA Astrophysics Data System (ADS)

    Harbord, David William Cameron

    This thesis consists of three self-contained papers on the analysis of electricity auctions written over a period of twelve years. The first paper models price competition in a decentralized wholesale market for electricity as a first-price, sealed-bid, multi-unit auction. In both the pure and mixed-strategy equilibria of the model, above marginal cost pricing and inefficient despatch of generating units occur. An alternative regulatory pricing rule is considered and it is shown that offering to supply at marginal cost can be induced as a dominant strategy for all firms. The second paper analyses strategic interaction between long-term contracts and price competition in the British electricity wholesale market, and confirms that forward contracts will tend to put downward pressure on spot market prices. A 'strategic commitment' motive for selling forward contracts is also identified: a generator may commit itself to bidding lower prices into the spot market in order to ensure that it will be despatched with its full capacity. The third paper characterizes bidding behavior and market outcomes in uniform and discriminatory electricity auctions. Uniform auctions result in higher average prices than discriminatory auctions, but the ranking in terms of productive efficiency is ambiguous. The comparative effects of other market design features, such as the number of steps in suppliers' bid functions, the duration of bids and the elasticity of demand are analyzed. The paper also clarifies some methodological issues in the analysis of electricity auctions. In particular we show that analogies with continuous share auctions are misplaced so long as firms are restricted to a finite number of bids.

  2. Non-double-couple mechanisms of microearthquakes induced by hydraulic fracturing

    USGS Publications Warehouse

    Sileny, J.; Hill, D.P.; Eisner, L.; Cornet, F.H.

    2009-01-01

    We have inverted polarity and amplitude information of representative microearthquakes to investigate source mechanisms of seismicity induced by hydraulic fracturing in the Carthage Cotton Valley, east Texas, gas field. With vertical arrays of four and eight three-component geophones in two monitoring wells, respectively, we were able to reliably determine source mechanisms of the strongest events with the best signal-to-noise ratio. Our analysis indicates predominantly non-double-couple source mechanisms with positive volumetric component consistent with opening cracks oriented close to expected hydraulic fracture orientation. Our observations suggest the induced events are directly the result of opening cracks by fluid injection, in contrast to many previous studies where the seismicity is interpreted to be primarily shearing caused by pore pressure diffusion into the surrounding rock or associated with shear stresses created at the hydraulic fracture tip. Copyright 2009 by the American Geophysical Union.

  3. Disentangling the various Mechanisms of neutrinoless double beta decay to extract the neutrino mass

    SciTech Connect

    Vergados, J. D.

    2011-12-16

    It is well known that there exist many mechanisms that may contribute to neutrinoless double beta decay. By exploiting the fact that the associated nuclear matrix elements are target dependent we show that, given definite experimental results on a sufficient number of targets, one can determine or sufficiently constrain all lepton violating parameters including the mass term. As a specific example we show that, given the observation of the 0{nu}{beta}{beta}-decay in three different nuclei, e.g. {sup 76}Ge, {sup 100}Mo and {sup 130}Te, and assuming just three active lepton number violating parameters, e.g. light and heavy neutrino mass mechanisms in left handed currents as well as R-parity breaking SUSY mechanism, one may determine all lepton violating parameters, provided that they are relatively real.

  4. Mechanisms governing the interfacial delamination of thermal barrier coating system with double ceramic layers

    NASA Astrophysics Data System (ADS)

    Xu, Rong; Fan, Xueling; Wang, T. J.

    2016-05-01

    A systematic study of factors affecting the interfacial delamination of thermal barrier coating system (TBCs) with double ceramic layers (DCL) is presented. Crack driving forces for delaminations at two weak interfaces are examined. The results show that a thicker outermost ceramic layer can induce dramatic increase in crack driving force and make the interface between two ceramic coatings become more prone to delamination. The behavior is shown to be more prominent in TBCs with stiffer outmost coating. The thickness ratio of two ceramic layers is an important parameter for controlling the failure mechanisms and determining the lifetime of DCL TBCs under inservice condition. By accounting for the influences of thickness ratio of two ceramic layers and interfacial fracture toughnesses of two involved interfaces, the fracture mechanism map of DCL TBCs has been constructed, in which different failure mechanisms are identified. The results quanlitatively agree with the aviliable experimental data.

  5. Shock Wave Boundary Layer Interaction Mechanism on a Double Wedge Geometry

    NASA Astrophysics Data System (ADS)

    Celik, Bayram; Barada, Mohammad Adel El Hajj Ali; Durna, Ahmet Selim

    2015-11-01

    A hypersonic test series by Swantek & Austin report complex shock wave boundary layer interaction mechanisms and unsteady surface heat flux from a double wedge geometry in a low enthalpy Mach 7 flow. In order to understand the physics of the flow and the heat transfer, we study the flow computationally and compare the results for the double wedge geometries, whose second angle is higher and lower than the maximum deflection angle at Mach 7. Apart from the numbers of comprehensive computational studies on the subject available in open literature, our study aims to describe the flow physics by taking the influence of both boundary layers that are formed on the two walls of the wedge into account. In addition to describing the flow and heat transfer mechanisms, we investigate the time for the flows to reach steady state. We evaluate the interaction mechanisms in term of instant and time average surface heat flux distributions. We perform all computations using a finite volume based compressible Navier-Stokes solver, rhoCentralFoam, which is one of the several compressible flow solvers of an open source software, openFOAM.

  6. 49 CFR 580.9 - Odometer record retention for auction companies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) ODOMETER DISCLOSURE REQUIREMENTS § 580.9 Odometer record retention for auction companies. Each auction company shall establish and... following records: (a) The name of the most recent owner (other than the auction company); (b) The name...

  7. Using Laboratory Experiments for Policymaking: An Example from the Georgia Irrigation Reduction Auction

    ERIC Educational Resources Information Center

    Cummings, Ronald G.; Holt, Charles A.; Laury, Susan K.

    2004-01-01

    In recent years, interest has been growing in policy applications of different auction systems. This paper reports a series of experiments that were used to design and implement an auction in a unique policymaking environment. In April 2000, the Georgia legislature passed a law that mandated that the state hold an auction in drought years to pay…

  8. Response of the electric conductivity of double-stranded DNA on moderate mechanical stretching stresses

    NASA Astrophysics Data System (ADS)

    Wolter, Mario; Woiczikowski, P. Benjamin; Elstner, Marcus; Kubař, Tomáš

    2012-02-01

    The response of charge transport in double-stranded DNA to mechanical pulling has been studied with a multiscale computational method using classical molecular dynamics simulation, approximative density-functional theory calculations and the Landauer-Büttiker theory. The effect depends on the exact nucleobase sequence notably, and this is explained in terms of structural changes of DNA upon stretching. The results of recent single-molecule experiments are interpreted on the basis of current results. Further, recommendations for the design of DNA sequences for nanoelectronic applications are formulated.

  9. Bolted Double-Lap Composite Joints Under Mechanical and Thermal Loading

    NASA Technical Reports Server (NTRS)

    Kradinov, V.; Barut, A.; Madenci, E.; Walker, Sandra P. (Technical Monitor)

    2000-01-01

    This study concerns the determination of the contact stresses and contact region around bolt holes and the bolt load distribution in single- and double-lap joints of composite laminates with arbitrarily located bolts under general mechanical loading conditions and uniform temperature change. The unknown contact stress distribution and contact region between the bolt and laminates and the interaction among the bolts require the bolt load distribution, as well as the contact stresses, to be as part of the solution. The present method is based on the complex potential theory and the variational formulation in order to account for bolt stiffness, bolt-hole clearance, and finite geometry of the composite laminates.

  10. Non-double-couple earthquake mechanisms at the Hengill-Grensdalur volcanic complex, southwest Iceland

    USGS Publications Warehouse

    Julian, B.R.; Miller, A.D.; Foulger, G.R.

    1997-01-01

    The Hengill-Grensdalur area in Iceland generates frequent small non-double-couple earthquakes with explosive volumetric components. We collected high quality three-component digital recordings of 4,000 earthquakes on a purpose-designed, 32-station network in 1991, and determined focal mechanisms for 100 of the best-recorded earthquakes by inverting amplitude ratios. Many of the mechanisms are consistent, within the errors, with simultaneous shear and tensile faulting, with tensile faults parallel to the local spreading ridge, and shear faulting similar to that in the South Iceland transform-fault zone. Some events cannot be explained by this model, however, and require other processes, such as crack closing and partial compensation of tensile cracks by fluid flow.

  11. Molecular Dynamics Study of Double-Walled Carbon Nanotubes for Nano-Mechanical Manipulation

    NASA Astrophysics Data System (ADS)

    Kimoto, Yoshihisa; Mori, Hideki; Mikami, Tomohito; Akita, Seiji; Nakayama, Yoshikazu; Higashi, Kenji; Hirai, Yoshihiko

    2005-04-01

    Double-walled carbon nanotubes (DWNTs) are expected to be useful as elements in nano-mechanical systems such as nanobearings and nanosliders. A molecular dynamics simulation is carried out to estimate the relative motion between the inner and outer tubes. The force required to pull the inner tube out of the outer tube is evaluated quantitatively by pulling the inner tube under a constant velocity for DWNTs with various inter-tube spacings and chiralities. When the inner tube is pulled under smaller constant force, the inner tube vibrates inside the outer tube without being pulled out, and an energetics is applied to explain the critical force and vibrational amplitude. The constant force induces not only vibration along the tube axis but also rotation around the tube axis, which indicates the possibility of creating a slider crank mechanism using a DWNT.

  12. Multi-unit auctions with budget-constrained bidders

    NASA Astrophysics Data System (ADS)

    Ghosh, Gagan Pratap

    In my dissertation, I investigate the effects of budget-constraints in multi-unit auctions. This is done in three parts. First, I analyze a case where all bidders have a common budget constraint. Precisely, I analyze an auction where two units of an object are sold at two simultaneous, sealed bid, first-price auctions, to bidders who have demand for both units. Bidders differ with respect to their valuations for the units. All bidders have an identical budget constraint which binds their ability to spend in the auction. I show that if valuation distribution is atom-less, then their does not exist any symmetric equilibrium in this auction game. In the second and third parts of my thesis, I analyze the sale of licenses for the right to drill for oil and natural gas in the Outer Continental Shelf (OCS) of the United States. These sales are conducted using simultaneous sealed-bid first-price auctions for multiple licenses, each representing a specific area (called a tract). Using aspects of observed bidding-behavior, I first make a prima facie case that bidders are budget-constrained in these auctions. In order to formalize this argument, I develop a simple extension of the standard model (where bidders differ in their valuations for the objects) by incorporating (random) budgets for the bidders. The auction-game then has a two-dimensional set of types for each player. I study the theoretical properties of this auction, assuming for simplicity that two units are being sold. I show that this game has an equilibrium in pure strategies that is symmetric with respect to the players and with respect to the units. The strategies are essentially pure in the sense that each bidder-type has a unique split (up to a permutation) of his budget between the two auctions. I then characterize the equilibrium in terms of the bid-distribution and iso-bid curves in the value-budget space. I derive various qualitative features of this equilibrium, among which are: (1) under mild

  13. Application for Single Price Auction Model (SPA) in AC Network

    NASA Astrophysics Data System (ADS)

    Wachi, Tsunehisa; Fukutome, Suguru; Chen, Luonan; Makino, Yoshinori; Koshimizu, Gentarou

    This paper aims to develop a single price auction model with AC transmission network, based on the principle of maximizing social surplus of electricity market. Specifically, we first formulate the auction market as a nonlinear optimization problem, which has almost the same form as the conventional optimal power flow problem, and then propose an algorithm to derive both market clearing price and trade volume of each player even for the case of market-splitting. As indicated in the paper, the proposed approach can be used not only for the price evaluation of auction or bidding market but also for analysis of bidding strategy, congestion effect and other constraints or factors. Several numerical examples are used to demonstrate effectiveness of our method.

  14. Insect-like flapping wing mechanism based on a double spherical Scotch yoke.

    PubMed

    Galiński, Cezary; Zbikowski, Rafał

    2005-06-22

    We describe the rationale, concept, design and implementation of a fixed-motion (non-adjustable) mechanism for insect-like flapping wing micro air vehicles in hover, inspired by two-winged flies (Diptera). This spatial (as opposed to planar) mechanism is based on the novel idea of a double spherical Scotch yoke. The mechanism was constructed for two main purposes: (i) as a test bed for aeromechanical research on hover in flapping flight, and (ii) as a precursor design for a future flapping wing micro air vehicle. Insects fly by oscillating (plunging) and rotating (pitching) their wings through large angles, while sweeping them forwards and backwards. During this motion the wing tip approximately traces a "figure-of-eight" or a "banana" and the wing changes the angle of attack (pitching) significantly. The kinematic and aerodynamic data from free-flying insects are sparse and uncertain, and it is not clear what aerodynamic consequences different wing motions have. Since acquiring the necessary kinematic and dynamic data from biological experiments remains a challenge, a synthetic, controlled study of insect-like flapping is not only of engineering value, but also of biological relevance. Micro air vehicles are defined as flying vehicles approximately 150 mm in size (hand-held), weighing 50-100g, and are developed to reconnoitre in confined spaces (inside buildings, tunnels, etc.). For this application, insect-like flapping wings are an attractive solution and hence the need to realize the functionality of insect flight by engineering means. Since the semi-span of the insect wing is constant, the kinematics are spatial; in fact, an approximate figure-of-eight/banana is traced on a sphere. Hence a natural mechanism implementing such kinematics should be (i) spherical and (ii) generate mathematically convenient curves expressing the figure-of-eight/banana shape. The double spherical Scotch yoke design has property (i) by definition and achieves (ii) by tracing

  15. Competition in the economic crisis: Analysis of procurement auctions

    PubMed Central

    Gugler, Klaus; Weichselbaumer, Michael; Zulehner, Christine

    2015-01-01

    We study the effects of the recent economic crisis on firms׳ bidding behavior and markups in sealed bid auctions. Using data from Austrian construction procurements, we estimate bidders׳ construction costs within a private value auction model. We find that markups of all bids submitted decrease by 1.5 percentage points in the recent economic crisis, markups of winning bids decrease by 3.3 percentage points. We also find that without the government stimulus package this decrease would have been larger. These two pieces of evidence point to pro-cyclical markups. PMID:25673884

  16. A GRAVITATIONAL DOUBLE-SCATTERING MECHANISM FOR GENERATING HIGH-VELOCITY OBJECTS DURING HALO MERGERS

    SciTech Connect

    Samsing, Johan

    2015-02-01

    We present a dynamical model that describes how halo particles can receive a significant energy kick from the merger between their own host halo and a target halo. This could provide a possible explanation for some high-velocity objects, including extended systems like globular clusters (GCs). In the model we especially introduce a double-scattering mechanism, where a halo particle receives a significant part of its total energy kick by first undergoing a gravitational deflection by the target halo and subsequently by its original host halo. This generates an energy kick that is due to the relative velocity between the halos during the deflections. We derive analytically the total kick energy of the particle, which is composed of energy from the double-scattering mechanism and tidal fields, as a function of its position in its original host halo just before merger. In the case of a 1:10 merger, we find that the presented mechanisms can easily generate particles with a velocity approximately two times the virial velocity of the target halo. This motivates us to suggest that the high velocity of the recently discovered GC HVGC-1 can be explained by a head-on halo merger. Finally, we illustrate the orbital evolution of high-velocity particles outside the virial sphere of the target halo by solving the equation of motion in an expanding universe. We find a sweet spot around a scale factor of 0.3-0.5 for ejecting particles into large orbits, which can easily reach beyond approximately five virial radii.

  17. A Gravitational Double-scattering Mechanism for Generating High-velocity Objects during Halo Mergers

    NASA Astrophysics Data System (ADS)

    Samsing, Johan

    2015-02-01

    We present a dynamical model that describes how halo particles can receive a significant energy kick from the merger between their own host halo and a target halo. This could provide a possible explanation for some high-velocity objects, including extended systems like globular clusters (GCs). In the model we especially introduce a double-scattering mechanism, where a halo particle receives a significant part of its total energy kick by first undergoing a gravitational deflection by the target halo and subsequently by its original host halo. This generates an energy kick that is due to the relative velocity between the halos during the deflections. We derive analytically the total kick energy of the particle, which is composed of energy from the double-scattering mechanism and tidal fields, as a function of its position in its original host halo just before merger. In the case of a 1:10 merger, we find that the presented mechanisms can easily generate particles with a velocity approximately two times the virial velocity of the target halo. This motivates us to suggest that the high velocity of the recently discovered GC HVGC-1 can be explained by a head-on halo merger. Finally, we illustrate the orbital evolution of high-velocity particles outside the virial sphere of the target halo by solving the equation of motion in an expanding universe. We find a sweet spot around a scale factor of 0.3-0.5 for ejecting particles into large orbits, which can easily reach beyond approximately five virial radii.

  18. Determination of effective mechanical properties of a double-layer beam by means of a nano-electromechanical transducer

    SciTech Connect

    Hocke, Fredrik; Pernpeintner, Matthias; Gross, Rudolf; Zhou, Xiaoqing; Kippenberg, Tobias J.; Schliesser, Albert; Huebl, Hans

    2014-09-29

    We investigate the mechanical properties of a doubly clamped, double-layer nanobeam embedded into an electromechanical system. The nanobeam consists of a highly pre-stressed silicon nitride and a superconducting niobium layer. By measuring the mechanical displacement spectral density both in the linear and the nonlinear Duffing regime, we determine the pre-stress and the effective Young's modulus of the nanobeam. An analytical double-layer model quantitatively corroborates the measured values. This suggests that this model can be used to design mechanical multilayer systems for electro- and optomechanical devices, including materials controllable by external parameters such as piezoelectric, magnetostrictive, or in more general multiferroic materials.

  19. Molecular spintronics in mixed-valence magnetic dimers: the double-exchange blockade mechanism.

    PubMed

    Soncini, Alessandro; Mallah, Talal; Chibotaru, Liviu F

    2010-06-16

    We theoretically investigate the charge and spin transport through a binuclear Fe(III)Fe(III) iron complex connected to two metallic electrodes. During the transport process, the Fe(III)Fe(III) dimer undergoes a one-electron reduction (Coulomb blockade transport regime), leading to the reduced mixed-valence Fe(II) Fe(III) species. For such a system, the additional electron may be fully delocalized leading to the stabilization of the highest spin ground state S = 9/2 by the double exchange mechanism, while the original Fe(III)Fe(III) has usually an S = 0 spin ground state due to the antiferromagnetic exchange coupling between the two Fe(III) ions. Intuitively, the spin delocalization within the mixed-valence complex may be thought to favor charge and spin transport through the molecule between the two metallic electrodes. Contrary to such an intuitive concept, we find that the increased delocalization leads in fact to a blocking of the transport, if the exchange coupling interaction within the Fe(III)Fe(III) dimer is antiferromagnetic. This is due to the violation of the spin angular momentum conservation, where a change of half a unit of spin (DeltaS = 1/2) is allowed between two different redox states of the molecule. The result is explained in terms of a double-exchange blockade mechanism, triggered by the interplay between spin delocalization and antiferromagnetic coupling between the magnetic cores. Consequently, ferromagnetically coupled dimers are shown not to be affected by the double-exchange blockade mechanism. The situation is evocative of the onset and removal of giant magnetoresistance in the conductance of diamagnetic layers, as a function of the relative alignment of the magnetization of two weakly antiferromagnetically coupled ferromagnetic contacts. Numerical simulations accounting for the effect of vibronic coupling show that the spin current increases as a function of spin delocalization in Class I and Class II mixed-valence dimers. The signature

  20. Forming mechanism of the bipolar resistance switching in double-layer memristive nanodevices

    NASA Astrophysics Data System (ADS)

    Lee, S. B.; Yoo, H. K.; Kim, K.; Lee, J. S.; Kim, Y. S.; Sinn, S.; Lee, D.; Kang, B. S.; Kahng, B.; Noh, T. W.

    2012-08-01

    To initiate resistance switching phenomena, it is usually necessary to apply a strong electric field to a sample. This forming process poses very serious obstacles in real nanodevice applications. In unipolar resistance switching (URS), it is well known that the forming originates from soft dielectric breakdown. However, the forming in bipolar resistance switching (BRS) is poorly understood. In this study, we investigated the forming processes in Pt/Ta2O5/TaOx/Pt and Pt/TaOx/Pt nanodevices, which showed BRS and URS, respectively. By comparing the double- and single-layer systems, we were able to observe differences in the BRS and URS forming processes. Using computer simulations based on an ‘interface-modified random circuit breaker network model’, we could explain most of our experimental observations. This success suggests that the BRS forming in our Pt/Ta2O5/TaOx/Pt double-layer system can occur via two processes, i.e., polarity-dependent resistance switching in the Ta2O5 layer and soft dielectric breakdown in the TaOx layer. This forming mechanism can be used to improve the performance of BRS devices. For example, we could improve the endurance properties of Pt/Ta2O5/TaOx/Pt cells by using a small forming voltage.

  1. Double channel mechanically tunable terahertz filter based on parallel plate waveguide cavities

    NASA Astrophysics Data System (ADS)

    Chen, Lin; Zhu, Yiming

    2012-12-01

    Theoretical and experimental works were carried out on a double channel mechanically tunable terahertz filter integrated with parallel plate waveguide cavities. The filter includes two rectangular grooves on upper and bottom plates of waveguide, respectively. The filter frequencies can be quasilinearly tuned by altering the overlap length between two rectangle grooves on metal plates. From the experiment, we found low (high) resonant frequency can be adjusted from 0.417(0.346) THz to 0.399(0.374) THz when the overlap length is altered from 0 to 500 μm, respectively. The Q values can reach 46 with the resonant frequency (0.41THz), overlap length (220 μm) and waveguide spacing (650 μm). Theoretical results show good agreement with experiment.

  2. [Plasma temperature calculation and coupling mechanism analysis of laser-double wire hybrid welding].

    PubMed

    Zheng, Kai; Li, Huan; Yang, Li-Jun; Gu, Xiao-Yan; Gao, Ying

    2013-04-01

    The plasma radiation of laser-double wire hybrid welding was collected by using fiber spectrometer, the coupling mechanism of arc with laser was studied through high-speed photography during welding process, and the temperature of hybrid plasma was calculated by using the method of Boltzmann plot. The results indicated that with laser hybrid, luminance was enhanced; radiation intensity became stronger; arc was attracted to the laser point; cross section contracted and arc was more stable. The laser power, welding current and arc-arc distance are important factors that have great influence on electron temperature. Increase in the laser power, amplification of welding current and reduction of arc-arc distance can all result in the rise of temperature. PMID:23841392

  3. Structural Basis for Elastic Mechanical Properties of the DNA Double Helix

    PubMed Central

    Kim, Young-Joo; Kim, Do-Nyun

    2016-01-01

    In this article, we investigate the principal structural features of the DNA double helix and their effects on its elastic mechanical properties. We develop, in the pursuit of this purpose, a helical continuum model consisting of a soft helical core and two stiff ribbons wrapping around it. The proposed model can reproduce the negative twist-stretch coupling of the helix successfully as well as its global stretching, bending, and torsional rigidities measured experimentally. Our parametric study of the model using the finite element method further reveals that the stiffness of phosphate backbones is a crucial factor for the counterintuitive overwinding behavior of the duplex and its extraordinarily high torsional rigidity, the major-minor grooves augment the twist-stretch coupling, and the change of the helicity might be responsible for the transition from a negative to a positive twist-stretching coupling when a tensile force is applied to the duplex. PMID:27055239

  4. 3+2 neutrino scheme from a singular double seesaw mechanism

    SciTech Connect

    McDonald, K.L.; McKellar, B.H.J.; Mastrano, A.

    2004-09-01

    We obtain a 3+2 neutrino spectrum within a left-right symmetric framework by invoking a singular double seesaw mechanism. Higgs doublets are employed to break SU{sub R}(2) and three additional fermions, singlets under the left-right symmetric gauge group, are included. The introduction of a singularity into the singlet fermion Majorana mass matrix results in a light neutrino sector of three neutrinos containing predominantly {nu}{sub {alpha}}{sub L}, {alpha}=e,{mu},{tau}, separated from two neutrinos containing a small {nu}{sub {alpha}}{sub L} component. The resulting active-sterile mixing in the 5x5 mixing matrix is specified once the mass eigenvalues and the 3x3 submatrix corresponding to the Pontecorvo-Maki-Nakagawa-Sakata (PMNS) mixing matrix are known.

  5. Ab initio bubble-driven denaturation of double-stranded DNA: Self-mechanical theory.

    PubMed

    Kuetche, Victor K

    2016-07-21

    Among the different theoretical models of the open-site-driven DNA-denaturation found in the literature, very few interests are actually paid to the fundamental unzipping process of the double-stranded DNA within the vicinity of its ground state condensate. In this paper, we address an alternative to better understand the process of denaturation of such a macromolecule by investigating the onset of its dynamics around its equilibrium state. We show that from the initiation of the transcription bubble by the promoter to the termination state, the open-states of the strands evolve dynamically while generating some localized waveguide channels with elastic scattering properties. We properly discuss the nonlinear dynamics of these structures within the viewpoint of the self-mechanical theory while inferring to the physical structure of the findings and their potential issues. PMID:27113786

  6. Superior Mechanical Properties of Double-Network Hydrogels Reinforced by Carbon Nanotubes without Organic Modification

    PubMed Central

    Dong, Weifu; Huang, Chiguang; Wang, Yang; Sun, Yujie; Ma, Piming; Chen, Mingqing

    2013-01-01

    A facile method is developed to fabricate nanocomposite double-network (DN) gels with excellent mechanical properties, which do not fracture upon loading up to 78 MPa and a strain above 0.98, by compositing of carbon nanotubes (CNTs) without organic modification. Investigations of swelling behaviors, and compressive and tensile properties indicate that equilibrium swelling ratio, compressive modulus and stress, fracture stress, Young’s modulus, and yield stress are significantly improved in the presence of CNTs. Scanning electron microscopy (SEM) reveals that the pore size of nanocomposite DN gels is decreased and some embedded micro-network structures are observed on the fracture surface in comparison to DN gels without CNTs, which leads to the enhancement of mechanical properties. The compressive loading-unloading behaviors show that the area of hysteresis loop, dissipated energy, for the first compressive cycle, increases with addition of CNTs, which is much higher than that for the successive cycles. Furthermore, the energy dissipation mechanism, similar to the Mullins effect observed in filled rubbers, is demonstrated for better understanding the nanocomposite DN polymer gels with CNTs. PMID:24232456

  7. Double-ionization mechanisms of the argon dimer in intense laser fields

    SciTech Connect

    Ulrich, B.; Vredenborg, A.; Malakzadeh, A.; Meckel, M.; Cole, K.; Jahnke, T.; Doerner, R.; Smolarski, M.; Chang, Z.

    2010-07-15

    We have measured the two-site double ionization of argon dimers by ultrashort laser pulses leading to fragmentation into two singly charged argon ions. Contrary to the expectations from a pure Coulomb explosion following rapid removal of one electron from each of the atoms, we find three distinct peaks in the kinetic energy release (KER) distribution. By measuring the angular distribution of the fragment ions and the vector momentum of one of the emitted electrons for circular and linear laser polarization, we are able to unravel the ionization mechanisms leading to the three features in the KER. The most abundant one results from tunnel ionization at one site followed by charge-enhanced tunnel ionization of the second atom. The second mechanism, which leads to a higher KER we identify as sequential tunnel ionization of both atoms accompanied by excitation. The third mechanism is present with linearly polarized light only. It is most likely a frustrated triple ionization, where the third electron does not escape but is trapped in a Rydberg state.

  8. Teaching Auction Strategy Using Experiments Administered Via the Internet

    ERIC Educational Resources Information Center

    Asker, John; Grosskopf, Brit; McKinney, C. Nicholas; Niederle, Muriel; Roth, Alvin E.; Weizsacker, Georg

    2004-01-01

    The authors present an experimental design used to teach concepts in the economics of auctions and implications for e-Business procurement. The experiment is easily administered and can be adapted to many different treatments. The chief innovation is that it does not require the use of a lab or class time. Instead, the design can be implemented on…

  9. Making Marketing Principles Tangible: Online Auctions as Living Case Studies

    ERIC Educational Resources Information Center

    Wood, Charles M.; Suter, Tracy A.

    2004-01-01

    This article presents an effective course supplement for Principles of Marketing classes. An experiential project involving online auctions is offered to instructors seeking to create a more participatory student environment and an interactive teaching style. A number of learning points are illustrated that allow instructors to use an auction…

  10. Understanding Persuasive Online Sales Messages from eBay Auctions

    ERIC Educational Resources Information Center

    White, Barbara Jo; Clapper, Danial; Noel, Rita; Fortier, Jenny; Grabolosa, Pierre

    2007-01-01

    Online auctions are dominated by eBay, which started bringing together buyers and sellers in 1995. eBay product listings can easily be used in business communication courses to better understand online sales messages. One great advantage is that the vast majority of nearly 15 million listings a day are written and assembled by everyday consumers…

  11. Mechanisms of Steady and Oscillatory Double-component Convection Due To Different Boundary Conditions

    NASA Astrophysics Data System (ADS)

    Tsitverblit, Naftali

    The effects of different boundary conditions on the behavior of double-component fluid are of basic significance for the ocean processes up to the scales of the global ocean thermohaline circulation [Walin, Palaeogeogr. Palaeoclimatol. Palaeoecol. 50, 323 (1985)]. One major aspect of such flows is that the effect of different boundary conditions can be conceptually analogous to that of different diffusivities in the classi- cal double-diffusion [Welander, Tellus, Ser. A 41, 66 (1989); Tsitverblit, Phys. Fluids 9, 2458 (1997); ibid. 11, 2516 (1999); Phys. Rev. E 62, R7591 (2000)]. This work reports the existence of a novel mechanism of double-component convection resulting from different boundary conditions, whose nature is unrelated to differential diffu- sion. This mechanism emerges in a horizontal layer of Boussinesq fluid as a stable stratification due to flux boundary conditions is added to an unstable gradient speci- fied by fixed boundary values. A large enough perturbation substantially decreases the stable flux gradient but fails to mix the unstable fixed-value gradient. Steady finite- amplitude flows reminiscent of Rayleigh--Benard convection then arise even as the net background stratification is stable. At sufficiently large Rayleigh numbers, con- tinuation of such flows into the finite-amplitude states in Tsitverblit (2000) exhibits a hysteresis region in the slot inclination angle, due to the dissimilar nature of these two convective flows. Welander's (1989) oscillatory instability is also analyzed with the focus on the compensating across-slot gradients. In the inviscid fluid, k = 0 is the most unstable wave number, with the perturbation frequency c = 0. The long- wavelength expansion yields the critical (joint) Rayleigh number, Rac, and group ve- locity, k (c/k), for k = 0 as Rac = 12(k) and k = c c 2 c 60/7. [Generally, at k = 0, the critical (fixed-value) Rayleigh number Rac = (2Ras + 5040)/51 and 12(k) = Ras; Ras being the flux Rayleigh number

  12. Insect-like flapping wing mechanism based on a double spherical Scotch yoke

    PubMed Central

    Galiński, Cezary; Żbikowski, Rafał

    2005-01-01

    We describe the rationale, concept, design and implementation of a fixed-motion (non-adjustable) mechanism for insect-like flapping wing micro air vehicles in hover, inspired by two-winged flies (Diptera). This spatial (as opposed to planar) mechanism is based on the novel idea of a double spherical Scotch yoke. The mechanism was constructed for two main purposes: (i) as a test bed for aeromechanical research on hover in flapping flight, and (ii) as a precursor design for a future flapping wing micro air vehicle. Insects fly by oscillating (plunging) and rotating (pitching) their wings through large angles, while sweeping them forwards and backwards. During this motion the wing tip approximately traces a ‘figure-of-eight’ or a ‘banana’ and the wing changes the angle of attack (pitching) significantly. The kinematic and aerodynamic data from free-flying insects are sparse and uncertain, and it is not clear what aerodynamic consequences different wing motions have. Since acquiring the necessary kinematic and dynamic data from biological experiments remains a challenge, a synthetic, controlled study of insect-like flapping is not only of engineering value, but also of biological relevance. Micro air vehicles are defined as flying vehicles approximately 150 mm in size (hand-held), weighing 50–100 g, and are developed to reconnoitre in confined spaces (inside buildings, tunnels, etc.). For this application, insect-like flapping wings are an attractive solution and hence the need to realize the functionality of insect flight by engineering means. Since the semi-span of the insect wing is constant, the kinematics are spatial; in fact, an approximate figure-of-eight/banana is traced on a sphere. Hence a natural mechanism implementing such kinematics should be (i) spherical and (ii) generate mathematically convenient curves expressing the figure-of-eight/banana shape. The double spherical Scotch yoke design has property (i) by definition and achieves (ii) by

  13. 77 FR 57085 - Mobility Fund Phase I Auction; Release of Files with Recalculated Road Miles for Auction 901...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    .../ecfs/ . 1. In the Auction 901 Procedures Public Notice, 77 FR 32092, May 31, 2012, the Bureaus... Notice, 77 FR 7152, February 10, 2012, in calculating the number of road miles associated with each eligible census block, the Bureaus used the sum of linear road miles within the block plus half of the...

  14. Separation of Recollision Mechanisms in Nonsequential Strong Field Double Ionization of Ar: The Role of Excitation Tunneling

    SciTech Connect

    Feuerstein, B.; Moshammer, R.; Fischer, D.; Dorn, A.; Schroeter, C. D.; Deipenwisch, J.; Crespo Lopez-Urrutia, J. R.; Hoehr, C.; Neumayer, P.; Ullrich, J.

    2001-07-23

    Vector momentum distributions of two electrons created in double ionization of Ar by 25fs, 0.25 PW/cm{sup 2} laser pulses at 795nm have been measured using a ''reaction microscope.'' At this intensity, where nonsequential ionization dominates, distinct correlation patterns are observed in the two-electron momentum distributions. A kinematical analysis of these spectra within the classical ''recollision model'' revealed an (e,2e) -like process and excitation with subsequent tunneling of the second electron as two different ionization mechanisms. This allows a qualitative separation of the two mechanisms demonstrating that excitation-tunneling is the dominant contribution to the total double ionization yield.

  15. A three-dimensional statistical mechanical model of folding double-stranded chain molecules

    NASA Astrophysics Data System (ADS)

    Zhang, Wenbing; Chen, Shi-Jie

    2001-05-01

    Based on a graphical representation of intrachain contacts, we have developed a new three-dimensional model for the statistical mechanics of double-stranded chain molecules. The theory has been tested and validated for the cubic lattice chain conformations. The statistical mechanical model can be applied to the equilibrium folding thermodynamics of a large class of chain molecules, including protein β-hairpin conformations and RNA secondary structures. The application of a previously developed two-dimensional model to RNA secondary structure folding thermodynamics generally overestimates the breadth of the melting curves [S-J. Chen and K. A. Dill, Proc. Natl. Acad. Sci. U.S.A. 97, 646 (2000)], suggesting an underestimation for the sharpness of the conformational transitions. In this work, we show that the new three-dimensional model gives much sharper melting curves than the two-dimensional model. We believe that the new three-dimensional model may give much improved predictions for the thermodynamic properties of RNA conformational changes than the previous two-dimensional model.

  16. Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms

    PubMed Central

    Raykov, Vasil; Marvin, Marcus E.; Louis, Edward J.; Maringele, Laura

    2016-01-01

    Inverted chromosome duplications or palindromes are linked with genetic disorders and malignant transformation. They are considered by-products of DNA double-strand break (DSB) repair: the homologous recombination (HR) and the nonhomologous end joining (NHEJ). Palindromes near chromosome ends are often triggered by telomere losses. An important question is to what extent their formation depends upon DSB repair mechanisms. Here we addressed this question using yeast genetics and comparative genomic hybridization. We induced palindrome formation by passaging cells lacking any form of telomere maintenance (telomerase and telomere recombination). Surprisingly, we found that DNA ligase 4, essential for NHEJ, did not make a significant contribution to palindrome formation induced by telomere losses. Moreover RAD51, important for certain HR-derived mechanisms, had little effect. Furthermore RAD52, which is essential for HR in yeast, appeared to decrease the number of palindromes in cells proliferating without telomeres. This study also uncovered an important role for Rev3 and Rev7 (but not for Pol32) subunits of polymerase ζ in the survival of cells undergoing telomere losses and forming palindromes. We propose a model called short-inverted repeat-induced synthesis in which DNA synthesis, rather than DSB repair, drives the inverted duplication triggered by telomere dysfunction. PMID:27334270

  17. Failure mechanisms of concrete slab-soil double-layer structure subjected to underground explosion

    NASA Astrophysics Data System (ADS)

    Tan, Z.; Zhang, W.; Cho, C.; Han, X.

    2014-09-01

    The failure mechanism of a concrete slab-soil double-layer structure subjected to an underground explosion was investigated by experimental and numerical methods in this paper. Two underground explosion depths of 150 and 350 mm were tested. The typical failure modes such as the conoid spall of concrete, the bulge of the concrete slab and the cavity in the soil were obtained experimentally. Numerical simulations of the experiments were performed using a hydrodynamic code to analyze the effects of both the stress wave and the expansion of the blast products. Based on the experimental and numerical results, the effects of explosive depth, blast wave front and expansion of the blast products on the failure modes and failure mechanisms were discussed. The underground explosion process at different explosion depths was also analyzed. The results show that attenuation of the stress wave in the soil is significant. The blast wave front and the expansion of the blast products play different roles at different explosion depths. At the explosion depth of 150 mm, the failure mode is mainly caused by a point load induced by the blast wave front, whereas at the depth of 350 mm a sphere-shaped load resulting from the expansion of the blast products is a key factor for failure.

  18. Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms.

    PubMed

    Raykov, Vasil; Marvin, Marcus E; Louis, Edward J; Maringele, Laura

    2016-08-01

    Inverted chromosome duplications or palindromes are linked with genetic disorders and malignant transformation. They are considered by-products of DNA double-strand break (DSB) repair: the homologous recombination (HR) and the nonhomologous end joining (NHEJ). Palindromes near chromosome ends are often triggered by telomere losses. An important question is to what extent their formation depends upon DSB repair mechanisms. Here we addressed this question using yeast genetics and comparative genomic hybridization. We induced palindrome formation by passaging cells lacking any form of telomere maintenance (telomerase and telomere recombination). Surprisingly, we found that DNA ligase 4, essential for NHEJ, did not make a significant contribution to palindrome formation induced by telomere losses. Moreover RAD51, important for certain HR-derived mechanisms, had little effect. Furthermore RAD52, which is essential for HR in yeast, appeared to decrease the number of palindromes in cells proliferating without telomeres. This study also uncovered an important role for Rev3 and Rev7 (but not for Pol32) subunits of polymerase ζ in the survival of cells undergoing telomere losses and forming palindromes. We propose a model called short-inverted repeat-induced synthesis in which DNA synthesis, rather than DSB repair, drives the inverted duplication triggered by telomere dysfunction. PMID:27334270

  19. Suppressing the mechanical quadrature error of a quartz double-H gyroscope through laser trimming

    NASA Astrophysics Data System (ADS)

    Zhao, Ke; Feng, Li-Hui; Wang, Qian-Qian; Liu, Ming-Zhi; Wang, Ben-Guo; Cui, Fang; Sun, Yu-Nan

    2013-11-01

    In this paper, we introduce a z-axis quartz gyroscope using a double-H tuning fork, which has a high sensitivity. However, it also causes a large mechanical quadrature error. The laser trimming method is used to suppress this error at quartz level. The trimming law is obtained through the finite element method (FEM). A femtosecond laser processing system is used to trim the gold balancing masses on the beams, and experimental results are basically consistent with the simulated ones. The mechanical quadrature error is suppressed by 96%, from 26.3° s-1 to 1.1° s-1. Nonlinearity changes from 1.48% to 0.30%, angular random walk (ARW) is reduced from 2.19° h-1/2 to 1.42° h-1/2, and bias instability is improved by a factor of 7.7, from 197.6° h-1 to 25.4° h-1.

  20. Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin.

    PubMed

    Cannan, Wendy J; Pederson, David S

    2016-01-01

    All organisms suffer double-strand breaks (DSBs) in their DNA as a result of exposure to ionizing radiation. DSBs can also form when replication forks encounter DNA lesions or repair intermediates. The processing and repair of DSBs can lead to mutations, loss of heterozygosity, and chromosome rearrangements that result in cell death or cancer. The most common pathway used to repair DSBs in metazoans (non-homologous DNA end joining) is more commonly mutagenic than the alternative pathway (homologous recombination mediated repair). Thus, factors that influence the choice of pathways used DSB repair can affect an individual's mutation burden and risk of cancer. This review describes radiological, chemical, and biological mechanisms that generate DSBs, and discusses the impact of such variables as DSB etiology, cell type, cell cycle, and chromatin structure on the yield, distribution, and processing of DSBs. The final section focuses on nucleosome-specific mechanisms that influence DSB production, and the possible relationship between higher order chromosome coiling and chromosome shattering (chromothripsis). PMID:26040249

  1. Characterization and mechanism of glass microwelding by double-pulse ultrafast laser irradiation.

    PubMed

    Wu, Sizhu; Wu, Dong; Xu, Jian; Hanada, Yasutaka; Suganuma, Ryo; Wang, Haiyu; Makimura, Testuya; Sugioka, Koji; Midorikawa, Katsumi

    2012-12-17

    We investigated the physical mechanism of high-efficiency glass microwelding by double-pulse ultrafast laser irradiation by measuring the dependences of the size of the heat-affected zone and the bonding strength on the delay time between the two pulses for delay time up to 80 ns. The size of the heat-affected zone increases rapidly when the delay time is increased from 0 to 12.5 ps. It then decreases dramatically when the delay time is further increased to 30 ps. It has a small peak around 100 ps. For delay time up to 40 ns, the size of the heat-affected zone exceeds that for a delay time of 0 ps, whereas for delay time over 60 ps, it becomes smaller than that for a delay time of 0 ps. The bonding strength exhibits the same tendency. The underlying physical mechanism is discussed in terms of initial electron excitation by the first pulse and subsequent excitation by the second pulse: specifically, the first pulse induces multiphoton ionization or tunneling ionization, while the second pulse induces electron heating or avalanche ionization or the second pulse is absorbed by the localized state. Transient absorption of glass induced by the ultrafast laser pulse was analyzed by an ultrafast pump-probe technique. We found that the optimum pulse energy ratio is unity. These results provide new insights into high-efficiency ultrafast laser microwelding of glass and suggest new possibilities for further development of other ultrafast laser processing techniques. PMID:23263129

  2. Fracture characteristics of HAZ-double edge notched weld joints with mechanical undermatching

    SciTech Connect

    Zarzour, J.F.; Kleinosky, M.J.

    1995-12-31

    Both experimental and finite element investigations were carried out on double edge notched weld joints in tension to determine the influence of material gradients across the heat affected zone (HAZ) on cracks located at three interface regions: (1) base plate and fine grain HAZ, (2) coarse grain HAZ and fine grain HAZ, (3) weld metal and coarse grain HAZ. For HY-100 steel with a 20 percent weld undermatch, it was concluded that for case (a), the different mechanical properties of both fine grain HAZ (FGHAZ) and coarse grain HAZ (CGHAZ), obtained with a novel indentation technique, greatly affect the near tip stress fields and promote yielding into the base plate. For case (b), the stress triaxiality at the crack tip is the highest and the plastic deformation is confined to the HAZ zone. Finally for case (c), the stress triaxiality is lowered by the presence of a softer weld metal. However, there is a possibility of gross section yielding through the weld area. The overall conclusion indicates that, in order to evaluate crack initiation in the HAZ, one needs to verify the relevant microstructure and determine the mechanical properties of each constituent, mainly, the CGHAZ and FGHAZ. In addition, the assumption of homogeneous HAZ properties may lead to erroneous conclusions.

  3. Onset of Double-Diffusive Convection in a Rectangular Cavity and Its Generation Mechanism

    NASA Astrophysics Data System (ADS)

    Mizushima, Jiro; Yasumizu, Yuto; Ohashi, Shunsuke

    2013-08-01

    Two-dimensional double diffusive convection in a binary fluid mixture filled in a container with a rectangular cross section is investigated by linear stability analyses, numerical simulations and numerical calculations of steady solutions in the present paper. We mainly consider an ethanol--water mixture as the binary fluid, in which heat and ethanol diffuse in different time scales affecting the fluid motion through buoyancy force and the Soret effect. The bottom of the cavity is kept at a higher temperature than the top, and the side boundary walls are assumed to be perfectly insulating. The impermeability condition of mass is applied on all the boundaries. We obtain the critical condition for the onset of double diffusive convection, and examine the flow field at the criticality. It is found that the most unstable mode of disturbance is oscillatory at the criticality for negative values of the separation number, though it is a steady mode of disturbance for positive or null values of the separation number. We discuss the driving mechanism of the steady and oscillatory convections by evaluating torques exerted on the fluid due to the buoyancy force, the pressure and the viscosity separately in each. We find in numerical simulations that the convection, even if it is oscillatory initially, always attains a steady state in due course in the case of a container with a square cross section. The bifurcation diagram of the steady convection is obtained numerically and the relation between the steady convection and the oscillatory mode of disturbance arising due to the linear instability is briefly discussed.

  4. Effect of Holding Time Before Solidification on Double-Oxide Film Defects and Mechanical Properties of Aluminum Alloys

    NASA Astrophysics Data System (ADS)

    El-Sayed, Mahmoud Ahmed; Salem, Hanadi A. G.; Kandeil, Abdelrazek Youssef; Griffiths, W. D.

    2011-12-01

    Double-oxide films (bifilms) have been held responsible for the variability in mechanical properties of aluminum castings. It has been suggested that the air entrapped inside a bifilm can react with the surrounding melt, leading to its consumption, which might improve the mechanical properties of the castings. In this work the effect of holding the melt before solidification on the distribution of mechanical properties, and by implication on entrained double oxide films, was investigated for several different aluminum alloys. The Weibull moduli of plate castings were determined under tensile conditions, and their fracture surfaces were examined for evidence of oxide films. The results suggested the occurrence of two competing mechanisms during the holding treatment: (1) the consumption of air inside the bifilms by reaction with the surrounding molten metal that may lead to improvements in mechanical properties and (2) the accompanying diffusion of hydrogen into the bifilms, which would be expected to have a deleterious effect on properties.

  5. The two-double mechanism of grid GIS resource discovery based on P2P

    NASA Astrophysics Data System (ADS)

    Zhang, Wen; Gao, Jinsong; Meng, Lingkui

    2006-10-01

    This paper researches on how to realize fast spatial resource discovery in distributed, heterogeneous Grid GIS environment. The characteristic of spatial data as multi-resource, huge volume, heterogeneous formats and time relativity decides that resource discovery in Grid environment is a very complex and exigent problem. Combining the central control with distributed management technology, this paper supposes a two-double resource discovery mechanism with both distributed resource catalog and dynamic hash table, which is just fit to the spatial data access characteristics that distributed in wide area but concentrated in local area. This method overcomes the single node bottleneck by setting up the dynamic service sections among middle layer metadata servers, and utilizes the improved DHT technology to route queries in high efficiency. With the new method, people multi-attribute resource discovery could be supported that not limited by the special keyword as P2P does. It is helpful to solve the spatial information discovery problem in complex environment, which could also enhance the extendibility and credibility of system.

  6. Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise.

    PubMed

    Soleimani, Reza; Heytens, Elke; Darzynkiewicz, Zbigniew; Oktay, Kutluk

    2011-08-01

    The mechanism of chemotherapy-induced acceleration of ovarian aging is not fully understood. We used doxorubicin, a widely used cancer chemotherapeutic, in a variety of in vivo xenograft, and in vitro models to investigate the impact of chemotherapy-induced aging on the human ovary. Doxorubicin caused massive double-strand-DNA-breaks in primordial follicles, oocytes, and granulosa cells in a dose dependent fashion as revealed by accumulating γH2AX foci. This damage was associated with apoptotic oocyte death and resulted in the activation of ATM. It appeared that the repair response enabled a minor proportion of oocytes (34.7%) and granulosa cells (12.1%) to survive while the majority succumbed to apoptotic death. Paradoxically, inhibition of ATM by KU-55933 resulted in improved survival, probably via prevention of downstream activation of TAp63α. Furthermore, doxorubicin caused vascular and stromal damage in the human ovary, which might impair ovarian function both pre- and post-menopausally. Chemotherapy-induced premature ovarian aging appears to result from a complex process involving both the germ- and non-germ cell components of the ovary. These effects may have clinical implications in aging both for premenopausal and postmenopausal cancer survivors. PMID:21869459

  7. A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.

    PubMed

    Janssen, Aniek; Breuer, Gregory A; Brinkman, Eva K; van der Meulen, Annelot I; Borden, Sean V; van Steensel, Bas; Bindra, Ranjit S; LaRocque, Jeannine R; Karpen, Gary H

    2016-07-15

    Repair of DNA double-strand breaks (DSBs) must be properly orchestrated in diverse chromatin regions to maintain genome stability. The choice between two main DSB repair pathways, nonhomologous end-joining (NHEJ) and homologous recombination (HR), is regulated by the cell cycle as well as chromatin context.Pericentromeric heterochromatin forms a distinct nuclear domain that is enriched for repetitive DNA sequences that pose significant challenges for genome stability. Heterochromatic DSBs display specialized temporal and spatial dynamics that differ from euchromatic DSBs. Although HR is thought to be the main pathway used to repair heterochromatic DSBs, direct tests of this hypothesis are lacking. Here, we developed an in vivo single DSB system for both heterochromatic and euchromatic loci in Drosophila melanogaster Live imaging of single DSBs in larval imaginal discs recapitulates the spatio-temporal dynamics observed for irradiation (IR)-induced breaks in cell culture. Importantly, live imaging and sequence analysis of repair products reveal that DSBs in euchromatin and heterochromatin are repaired with similar kinetics, employ both NHEJ and HR, and can use homologous chromosomes as an HR template. This direct analysis reveals important insights into heterochromatin DSB repair in animal tissues and provides a foundation for further explorations of repair mechanisms in different chromatin domains. PMID:27474442

  8. Methotrexatum intercalated layered double hydroxides: statistical design, mechanism explore and bioassay study.

    PubMed

    Wang, Xiao-Feng; Liu, Su-Qing; Li, Shu-Ping

    2015-04-01

    A series of methotrexatum intercalated layered double hydroxide (MTX/LDH for short) hybrids have been synthesized by a mechanochemical-hydrothermal method, the statistical experiments are planned and conducted to find out the critical factor influencing the physicochemical properties. Four variables, i.e., addition of NaOH solution, grinding duration, hydrothermal temperature and time, are chosen to play as the examined factors in the orthogonal design. Furthermore, three respective levels, i.e., high, medium and low levels, are conducted in the design. The resulting hybrids are then characterized by X-ray diffraction (XRD) patterns, transmission electron microscope (TEM) graphs and Zeta potentials. XRD diffractions indicate that MTX anions have been successfully intercalated into LDH interlayers and the amount of NaOH solution can change the gallery height greatly. The information from TEM graphs and Zeta potentials state that the increase of alkali solution gives rise to regular morphology and the increase of Zeta potentials. As a result of the statistical analysis, addition of alkali solution is the major factor affecting the morphology and drug-loading capacity. At last, the mechanism of particle growth is explored emphatically, and the anticancer efficacy of some MTX/LDH hybrids is estimated by MTT assay on A549 cells as well. PMID:25686957

  9. Large displacement behavior of double parallelogram flexure mechanisms with underconstraint eliminators

    DOE PAGESBeta

    Panas, Robert M.

    2016-06-23

    This paper presents a new analytical method for predicting the large displacement behavior of flexural double parallelogram (DP) bearings with underconstraint eliminator (UE) linkages. This closed-form perturbative Euler analysis method is able to – for the first time – directly incorporate the elastomechanics of a discrete UE linkage, which is a hybrid flexure element that is linked to ground as well as both stages on the bearing. The models are used to understand a nested linkage UE design, however the method is extensible to other UE linkages. Design rules and figures-of-merit are extracted from the analysis models, which provide powerfulmore » tools for accelerating the design process. The models, rules and figures-of-merit enable the rapid design of a UE for a desired large displacement behavior, as well as providing a means for determining the limits of UE and DP structures. This will aid in the adoption of UE linkages into DP bearings for precision mechanisms. Models are generated for a nested linkage UE design, and the performance of this DP with UE structure is compared to a DP-only bearing. As a result, the perturbative Euler analysis is shown to match existing theories for DP-only bearings with distributed compliance within ≈2%, and Finite Element Analysis for the DP with UE bearings within an average 10%.« less

  10. Detoxifying carcinogenic polyhalogenated quinones by hydroxamic acids via an unusual double Lossen rearrangement mechanism

    PubMed Central

    Zhu, Ben-Zhan; Zhu, Jun-Ge; Mao, Li; Kalyanaraman, Balaraman; Shan, Guo-Qiang

    2010-01-01

    Hydroxamic acids, which are best-known for their metal-chelating properties in biomedical research, have been found to effectively detoxify the carcinogenic polyhalogenated quinoid metabolites of pentachlorophenol and other persistent organic pollutants. However, the chemical mechanism underlying such detoxication is unclear. Here we show that benzohydroxamic acid (BHA) could dramatically accelerate the conversion of the highly toxic tetrachloro-1, 4-benzoquinone (p-chloranil) to the much less toxic 2,5-dichloro-3, 6-dihydroxy-1, 4-benzoquonine (chloranilic acid), with rate accelerations of up to 150,000-fold. In contrast, no enhancing effect was observed with O-methyl BHA. The major reaction product of BHA was isolated and identified as O-phenylcarbamyl benzohydroxamate. On the basis of these data and oxygen-18 isotope-labeling studies, we proposed that suicidal nucleophilic attack coupled with an unexpected double Lossen rearrangement reaction was responsible for this remarkable acceleration of the detoxication reaction. This is the first report of an unusually mild and facile Lossen-type rearrangement, which could take place under normal physiological conditions in two consecutive steps. Our findings may have broad biological and environmental implications for future research on hydroxamic acids and polyhalogenated quinoid carcinogens, which are two important classes of compounds of major biomedical and environmental interest. PMID:21076034

  11. Sp1 Facilitates DNA Double-Strand Break Repair through a Nontranscriptional Mechanism

    PubMed Central

    Beishline, Kate; Kelly, Crystal M.; Olofsson, Beatrix A.; Koduri, Sravanthi; Emrich, Jacqueline; Greenberg, Roger A.

    2012-01-01

    Sp1 is a ubiquitously expressed transcription factor that is phosphorylated by ataxia telangiectasia mutated kinase (ATM) in response to ionizing radiation and H2O2. Here, we show by indirect immunofluorescence that Sp1 phosphorylated on serine 101 (pSp1) localizes to ionizing radiation-induced foci with phosphorylated histone variant γH2Ax and members of the MRN (Mre11, Rad50, and Nbs1) complex. More precise analysis of occupancy of DNA double-strand breaks (DSBs) by chromatin immunoprecipitation (ChIP) shows that Sp1, like Nbs1, resides within 200 bp of DSBs. Using laser microirradiation of cells, we demonstrate that pSp1 is present at DNA DSBs by 7.5 min after induction of damage and remains at the break site for at least 8 h. Depletion of Sp1 inhibits repair of site-specific DNA breaks, and the N-terminal 182-amino-acid peptide, which contains targets of ATM kinase but lacks the zinc finger DNA binding domain, is phosphorylated, localizes to DSBs, and rescues the repair defect resulting from Sp1 depletion. Together, these data demonstrate that Sp1 is rapidly recruited to the region immediately adjacent to sites of DNA DSBs and is required for DSB repair, through a mechanism independent of its sequence-directed transcriptional effects. PMID:22826432

  12. Mechanisms of DNA Packaging by Large Double-Stranded DNA Viruses

    PubMed Central

    Rao, Venigalla B.; Feiss, Michael

    2016-01-01

    Translocation of viral double-stranded DNA (dsDNA) into the icosahedral prohead shell is catalyzed by TerL, a motor protein that has ATPase, endonuclease, and translocase activities. TerL, following endonucleolytic cleavage of immature viral DNA concatemer recognized by TerS, assembles into a pentameric ring motor on the prohead’s portal vertex and uses ATP hydrolysis energy for DNA translocation. TerL’s N-terminal ATPase is connected by a hinge to the C-terminal endonuclease. Inchworm models propose that modest domain motions accompanying ATP hydrolysis are amplified, through changes in electrostatic interactions, into larger movements of the C-terminal domain bound to DNA. In phage φ29, four of the five TerL subunits sequentially hydrolyze ATP, each powering translocation of 2.5 bp. After one viral genome is encapsidated, the internal pressure signals termination of packaging and ejection of the motor. Current focus is on the structures of packaging complexes and the dynamics of TerL during DNA packaging, endonuclease regulation, and motor mechanics. PMID:26958920

  13. Studying dielectric mechanism and magnetization of double perovskite Gd2NiMnO6 ceramic

    NASA Astrophysics Data System (ADS)

    Mohapatra, S. R.; Sahu, B.; Kaushik, S. D.; Singh, A. K.

    2016-05-01

    In the present work, the structure, dielectric and magnetic properties of Gd2NiMnO6 double perovskite have been studied. X-Ray diffraction study reveals the phase pure formation of the material that crystallizes into monoclinic phase (space group 'P21/n'). Surface morphology depicts heterogeneous grain distribution with average grain size of ~1 µm. Temperature dependent (50 - 330 K) dielectric measurements at different frequencies (0.5 - 50 kHz) relate to Maxwell-Wagner interfacial polarization model. Giant dielectric constant at 1 kHz for 300 K (ɛ' ~1900) is noticed as compared to that of 50 K (ɛ' ~10) coupled with a peak shift in tan loss towards higher temperature with frequency. The activation energy (0.24 eV) obtained using Arrhenius relation for thermally activated relaxor behavior of the material signifies an electron hopping mechanism between Ni2+ and Mn4+ cations. Lastly, M-H study shows `S' shape hysteresis loop at 50 K with remnant magnetization (Mr) of 0.72 µB/f.u. along with a linear plot for 300 K which reveals paramagnetic nature of the material.

  14. Mechanisms of DNA Packaging by Large Double-Stranded DNA Viruses.

    PubMed

    Rao, Venigalla B; Feiss, Michael

    2015-11-01

    Translocation of viral double-stranded DNA (dsDNA) into the icosahedral prohead shell is catalyzed by TerL, a motor protein that has ATPase, endonuclease, and translocase activities. TerL, following endonucleolytic cleavage of immature viral DNA concatemer recognized by TerS, assembles into a pentameric ring motor on the prohead's portal vertex and uses ATP hydrolysis energy for DNA translocation. TerL's N-terminal ATPase is connected by a hinge to the C-terminal endonuclease. Inchworm models propose that modest domain motions accompanying ATP hydrolysis are amplified, through changes in electrostatic interactions, into larger movements of the C-terminal domain bound to DNA. In phage ϕ29, four of the five TerL subunits sequentially hydrolyze ATP, each powering translocation of 2.5 bp. After one viral genome is encapsidated, the internal pressure signals termination of packaging and ejection of the motor. Current focus is on the structures of packaging complexes and the dynamics of TerL during DNA packaging, endonuclease regulation, and motor mechanics. PMID:26958920

  15. Design and Promotion Strategy of Marketing Platform of Aquatic Auction based on Internet

    NASA Astrophysics Data System (ADS)

    Peng, Jianliang

    For the online trade and promotion of aquatic products and related materials through the network between supply and demand, the design content and effective promotional strategies of aquatic auctions online marketing platform is proposed in this paper. Design elements involve the location of customer service, the basic function of the platform including the purchase of general orders, online auctions, information dissemination, and recommendation of fine products, human services, and payment preferences. Based on network and mobile e-commerce transaction support, the auction platform makes the transaction of aquatic products well in advance. The results are important practical value for the design and application of online marketing platform of aquatic auction.

  16. A Large Generator's Bids in an Electricity Supply Auction: Uniform Pricing vs. Pay-as-Bid Pricing

    NASA Astrophysics Data System (ADS)

    Yamamoto, Yoshihiro; Tezuka, Tetsuo

    A pay-as-bid auction has been adopted in a balancing market under New Electricity Trading Arrangements in England and Wales since 2001 instead of a uniform price auction previously used in a day-ahead pool market. In contrast, a spot market in Japan, where a general electric utility would be the main supplier, plans to employ a uniform price auction. In this paper we model an electricity spot market in which one large generator competes with many fringe generators to supply electricity, analyze how this large generator bids to maximize its profits, and report some implication for the design of this market. Three types of auction are analyzed: a highest-winning-bid pricing (HWB) uniform price auction, a lowest-losing-bid pricing (LLB) uniform price auction and a pay-as-bid auction. It is shown that the slope of the bid curve, which is obtained by plotting the large generator's bidding prices against its generation costs, are steeper in an LLB uniform price auction and flatter in a pay-as-bid auction than those in an HWB uniform price auction. This implies that an LLB uniform price auction or a pay-as-bid auction would make room for the fringe generators to win an auction.

  17. Mechanisms of double-strand-break repair during gene targeting in mammalian cells.

    PubMed Central

    Ng, P; Baker, M D

    1999-01-01

    In the present study, the mechanism of double-strand-break (DSB) repair during gene targeting at the chromosomal immunoglobulin mu-locus in a murine hybridoma was examined. The gene-targeting assay utilized specially designed insertion vectors genetically marked in the region of homology to the chromosomal mu-locus by six diagnostic restriction enzyme site markers. The restriction enzyme markers permitted the contribution of vector-borne and chromosomal mu-sequences in the recombinant product to be determined. The use of the insertion vectors in conjunction with a plating procedure in which individual integrative homologous recombination events were retained for analysis revealed several important features about the mammalian DSB repair process:The presence of the markers within the region of shared homology did not affect the efficiency of gene targeting.In the majority of recombinants, the vector-borne marker proximal to the DSB was absent, being replaced with the corresponding chromosomal restriction enzyme site. This result is consistent with either formation and repair of a vector-borne gap or an "end" bias in mismatch repair of heteroduplex DNA (hDNA) that favored the chromosomal sequence. Formation of hDNA was frequently associated with gene targeting and, in most cases, began approximately 645 bp from the DSB and could encompass a distance of at least 1469 bp.The hDNA was efficiently repaired prior to DNA replication.The repair of adjacent mismatches in hDNA occurred predominantly on the same strand, suggesting the involvement of a long-patch repair mechanism. PMID:10049929

  18. 78 FR 68839 - Tribal Mobility Fund Phase I Auction Rescheduled for February 25, 2014; Notice of Changes to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-15

    ...In this document, the Wireless Telecommunications and Wireline Competition Bureaus (the Bureaus) announce the rescheduling of Auction 902 and revise the dates and deadlines for the filing window for short- form applications and other auction...

  19. 75 FR 8703 - Auction of Lower and Upper Paging Bands Licenses Scheduled for May 25, 2010; Notice and Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... Public Notice, 74 FR 67221, December 18, 2009. i. Licenses to be Offered in Auction 87 2. Auction 87 will... Second Report and Order, 71 FR 26245, May 5, 2006, meaning that those preexisting relationships alone... seeking to participate in a Commission auction and select licenses in the same or overlapping markets....

  20. 7 CFR 29.75a - Display of burley tobacco on auction warehouse floors in designated markets.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Display of burley tobacco on auction warehouse floors... § 29.75a Display of burley tobacco on auction warehouse floors in designated markets. (a)(1) Each lot of burley tobacco displayed for sale on auction warehouse floors shall have a minimum space of...

  1. 31 CFR 356.22 - Does the Treasury have any limitations on auction awards?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Does the Treasury have any limitations on auction awards? 356.22 Section 356.22 Money and Finance: Treasury Regulations Relating to Money..., PUBLIC DEBT SERIES NO. 1-93) Determination of Auction Awards; Settlement § 356.22 Does the Treasury...

  2. Sold! The Elementary Classroom Auction as Learning Tool of Communication and Economics

    ERIC Educational Resources Information Center

    Boyd, Josh; Boyd, Gina

    2014-01-01

    An auction, though an economic tool, is essentially a performance dependent on communication (Smith, 1989). The auctioneer dictates the pace, asks for bids, and acknowledges responses; the enterprise is controlled by a voice (Boyce, 2001). Bidders must listen and respond strategically to the communication of the people around them. An auction…

  3. 30 CFR 285.220 - What auction format may MMS use in a lease sale?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 285.220 What auction format may MMS use... renewable energy leases and will use one of the following auction formats, as determined through the...

  4. 30 CFR 585.220 - What auction format may BOEM use in a lease sale?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 585.220 What auction format may... award renewable energy leases and will use one of the following auction formats, as determined...

  5. 30 CFR 285.220 - What auction format may MMS use in a lease sale?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 285... competitive auctions to award renewable energy leases and will use one of the following auction formats,...

  6. 30 CFR 585.220 - What auction format may BOEM use in a lease sale?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy Leases Competitive Lease Award Process § 585.220 What auction format may... award renewable energy leases and will use one of the following auction formats, as determined...

  7. Robust Multi-unit Auction Protocol against False-name Bids

    NASA Astrophysics Data System (ADS)

    Yokoo, Makoto; Sakurai, Yuko; Matsubara, Shigeo

    This paper presents a new multi-unit auction protocol (IR protocol) that is robust against false-name bids. Internet auctions have become an integral part of Electronic Commerce and a promising field for applying agent and Artificial Intelligence technologies. Although the Internet provides an excellent infrastructure for executing auctions, the possibility of a new type of cheating called false-name bids has been pointed out. A false-name bid is a bid submitted under a fictitious name. A protocol called LDS has been developed for combinatorial auctions of multiple different items and has proven to be robust against false-name bids. Although we can modify the LDS protocol to handle multi-unit auctions, in which multiple units of an identical item are auctioned, the protocol is complicated and requires the auctioneer to carefully pre-determine the combination of bundles to obtain a high social surplus or revenue. For the auctioneer, our newly developed IR protocol is easier to use than the LDS, since the combination of bundles is automatically determined in a flexible manner according to the declared evaluation values of agents. The evaluation results show that the IR protocol can obtain a better social surplus than that obtained by the LDS protocol.

  8. 75 FR 57947 - Auction of VHF Commercial Television Station Construction Permits Scheduled for February 15, 2011...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ...; Comment Sought on Competitive Bidding Procedures for Auction 90 AGENCY: Federal Communications Commission... scheduled to commence on February 15, 2011 (Auction 90). This document also seeks comment on competitive... the fair and efficient conduct of competitive bidding. In such cases, the Bureaus, in their...

  9. Are Structural Estimates of Auction Models Reasonable? Evidence from Experimental Data

    ERIC Educational Resources Information Center

    Bajari, Patrick; Hortacsu, Ali

    2005-01-01

    Recently, economists have developed methods for structural estimation of auction models. Many researchers object to these methods because they find the strict rationality assumptions to be implausible. Using bid data from first-price auction experiments, we estimate four alternative structural models: (1) risk-neutral Bayes-Nash, (2) risk-averse…

  10. 29 CFR 780.619 - Work “in connection with” livestock auction operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Work âin connection withâ livestock auction operations. 780... FAIR LABOR STANDARDS ACT Employment in Agriculture and Livestock Auction Operations Under the Section 13(b)(13) Exemption Requirements for Exemption § 780.619 Work “in connection with” livestock...

  11. 29 CFR 780.620 - Minimum wage for livestock auction work.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Minimum wage for livestock auction work. 780.620 Section 780.620 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... for Exemption § 780.620 Minimum wage for livestock auction work. The application of the exemption...

  12. 29 CFR 780.620 - Minimum wage for livestock auction work.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 3 2014-07-01 2014-07-01 false Minimum wage for livestock auction work. 780.620 Section 780.620 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... for Exemption § 780.620 Minimum wage for livestock auction work. The application of the exemption...

  13. 29 CFR 780.620 - Minimum wage for livestock auction work.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Minimum wage for livestock auction work. 780.620 Section 780.620 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... for Exemption § 780.620 Minimum wage for livestock auction work. The application of the exemption...

  14. 29 CFR 780.620 - Minimum wage for livestock auction work.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Minimum wage for livestock auction work. 780.620 Section 780.620 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... for Exemption § 780.620 Minimum wage for livestock auction work. The application of the exemption...

  15. 29 CFR 780.620 - Minimum wage for livestock auction work.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Minimum wage for livestock auction work. 780.620 Section 780.620 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... for Exemption § 780.620 Minimum wage for livestock auction work. The application of the exemption...

  16. 77 FR 15369 - Mobility Fund Phase I Auction GIS Data of Potentially Eligible Census Blocks

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-15

    ... COMMISSION Mobility Fund Phase I Auction GIS Data of Potentially Eligible Census Blocks AGENCY: Federal... information system (GIS) data for the census blocks potentially eligible for Mobility Fund Phase I support to...-0432 (TTY). SUPPLEMENTARY INFORMATION: This is a summary of the Mobility Fund Phase I Auction GIS...

  17. 77 FR 38061 - Mobility Fund Phase I Auction Supplemental Short-Form Instructions and Other Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ... Notice, 77 FR 32092, May 31, 2012, the Bureaus provided general instructions for completing FCC Form 180... COMMISSION Mobility Fund Phase I Auction Supplemental Short-Form Instructions and Other Information AGENCY... provide other information regarding Auction 901. DATES: Short-Form applications are due prior to 6 p.m....

  18. Teaching Marginal Cost, Supply, and Efficiency with an English-Auction Experiment.

    ERIC Educational Resources Information Center

    Bernard, John C.; Schulze, William

    2000-01-01

    Describes a computerized English-auction experiment that helps students to understand marginal cost and its interrelationships with supply and the efficiency of competitive markets. Explains that the English auction is in a market where there are many sellers (students) and one buyer (computer). States that this exercise offers a good introduction…

  19. The design and analysis of a double swivel toggle release mechanism for the Orbiter stabilized payload deployment system

    NASA Technical Reports Server (NTRS)

    King, Guy L.; Tsai, Ted

    1989-01-01

    The NASA Stabilized Payload Deployment System (SPDS) is discussed. The lightweight and heavy-duty system rolls payloads over the orbiter's side rather than ejecting them upward. The system will enhance the orbiter capability of carrying larger and heavier payloads. The design, function, and analysis of a new three-pin double swivel toggle release mechanism which is crucial to the successful deployment of the SPDS are described.

  20. A mechanism for weak double layers and coherent low-frequency electrostatic wave activity in the solar wind

    NASA Astrophysics Data System (ADS)

    Singh Lakhina, Gurbax; Singh, Satyavir

    2016-07-01

    A mechanism for the weak double layers and coherent low-frequency electrostatic wave activity observed by Wind spacecraft in the solar wind at 1 AU is proposed in terms of ion-acoustic solitons and double layers. The solar wind plasma is modelled by a three component plasma consisting of fluid hot protons, hot alpha particles streaming with respect to protons, and suprathermal electrons having κ- distribution. This system supports two types of, slow and fast, ion-acoustic solitary waves. The fast ion-acoustic mode is similar to the ion-acoustic mode of proton-electron plasma, and can support only positive potential solitons. The slow ion-acoustic mode is a new mode that occurs due to the presence of alpha particles. This mode can support both positive and negative solitons and double layers. An increase of the κ- index leads to an increase in the critical Mach number, maximum Mach number and the maximum amplitude of both slow and fast ion-acoustic solitons. The slow ion-acoustic double layer can explain the amplitudes and widths, but not shapes, of the weak double layers (WDLs) observed in the solar wind at 1 AU by Wind spacecraft. The Fourier transform of the slow ion-acoustic solitons/double layers would produce broadband low-frequency electrostatic waves having main peaks between 0.35 kHz to 1.6 kHz, with electric field in the range of E = (0.01 - 0.7 ) mV/m, in excellent agreement with the observed low-frequency electrostatic wave activity in the solar wind at 1 AU.

  1. Pricing strategies, the strength of bidding intentions, and online auction performance: a cross-cultural study.

    PubMed

    Peng, Yu-Shu; Jan, Lih-Tsyr

    2009-10-01

    Over the past decade, electronic markets based on the Internet, particularly online auctions, have become popular venues for conducting business. Previous studies often focused on the construction of the best bidding model, while few studies have tried to integrate multiple pricing strategies to predict the probability of closing an auction and the price premium. This study constructs a mediated model to examine the relationship among pricing strategies, the strength of bidding intentions, and online auction performance. The sample consists of 1,055 auctions of iPod MP3 players from eBay Web sites in Hong Kong, Singapore, Belgium, and France. Empirical results show that the pricing strategies directly influence both the probability of closing an auction and the level of price premium. The pricing strategies also indirectly influence the price premium through the mediating effect of the strength of bidding intentions. PMID:19817564

  2. Fault structure and mechanics of the Hayward Fault, California, from double-difference earthquake locations

    NASA Astrophysics Data System (ADS)

    Waldhauser, Felix; Ellsworth, William L.

    2002-03-01

    The relationship between small-magnitude seismicity and large-scale crustal faulting along the Hayward Fault, California, is investigated using a double-difference (DD) earthquake location algorithm. We used the DD method to determine high-resolution hypocenter locations of the seismicity that occurred between 1967 and 1998. The DD technique incorporates catalog travel time data and relative P and S wave arrival time measurements from waveform cross correlation to solve for the hypocentral separation between events. The relocated seismicity reveals a narrow, near-vertical fault zone at most locations. This zone follows the Hayward Fault along its northern half and then diverges from it to the east near San Leandro, forming the Mission trend. The relocated seismicity is consistent with the idea that slip from the Calaveras Fault is transferred over the Mission trend onto the northern Hayward Fault. The Mission trend is not clearly associated with any mapped active fault as it continues to the south and joins the Calaveras Fault at Calaveras Reservoir. In some locations, discrete structures adjacent to the main trace are seen, features that were previously hidden in the uncertainty of the network locations. The fine structure of the seismicity suggests that the fault surface on the northern Hayward Fault is curved or that the events occur on several substructures. Near San Leandro, where the more westerly striking trend of the Mission seismicity intersects with the surface trace of the (aseismic) southern Hayward Fault, the seismicity remains diffuse after relocation, with strong variation in focal mechanisms between adjacent events indicating a highly fractured zone of deformation. The seismicity is highly organized in space, especially on the northern Hayward Fault, where it forms horizontal, slip-parallel streaks of hypocenters of only a few tens of meters width, bounded by areas almost absent of seismic activity. During the interval from 1984 to 1998, when

  3. Fault structure and mechanics of the Hayward Fault, California from double-difference earthquake locations

    USGS Publications Warehouse

    Waldhauser, F.; Ellsworth, W.L.

    2002-01-01

    The relationship between small-magnitude seismicity and large-scale crustal faulting along the Hayward Fault, California, is investigated using a double-difference (DD) earthquake location algorithm. We used the DD method to determine high-resolution hypocenter locations of the seismicity that occurred between 1967 and 1998. The DD technique incorporates catalog travel time data and relative P and S wave arrival time measurements from waveform cross correlation to solve for the hypocentral separation between events. The relocated seismicity reveals a narrow, near-vertical fault zone at most locations. This zone follows the Hayward Fault along its northern half and then diverges from it to the east near San Leandro, forming the Mission trend. The relocated seismicity is consistent with the idea that slip from the Calaveras Fault is transferred over the Mission trend onto the northern Hayward Fault. The Mission trend is not clearly associated with any mapped active fault as it continues to the south and joins the Calaveras Fault at Calaveras Reservoir. In some locations, discrete structures adjacent to the main trace are seen, features that were previously hidden in the uncertainty of the network locations. The fine structure of the seismicity suggest that the fault surface on the northern Hayward Fault is curved or that the events occur on several substructures. Near San Leandro, where the more westerly striking trend of the Mission seismicity intersects with the surface trace of the (aseismic) southern Hayward Fault, the seismicity remains diffuse after relocation, with strong variation in focal mechanisms between adjacent events indicating a highly fractured zone of deformation. The seismicity is highly organized in space, especially on the northern Hayward Fault, where it forms horizontal, slip-parallel streaks of hypocenters of only a few tens of meters width, bounded by areas almost absent of seismic activity. During the interval from 1984 to 1998, when digital

  4. Synthetic aperture double exposure digital holographic interferometry for wide angle measurement and monitoring of mechanical displacements

    NASA Astrophysics Data System (ADS)

    Kujawinska, M.; Makowski, P.; Finke, G.; Zak, J.; Józwik, M.; Kozacki, T.

    2015-08-01

    A novel approach for wide angle registration and display of double exposure digital holograms of 3D objects under static or step-wise load is presented. The registration setup concept combines digital Fourier holography with synthetic aperture (SA) technique, which is equivalent to usage of a wide angle, spherically curved detector. The coherent object wavefields extracted from a pair of acquisitions collected in the synthetic aperture double exposure digital holographic interferometry scheme (SA DEDH) are utilized as the input for two different scenarios of investigation, which include (i) numerical determination of 2D phase difference fringes representing deformation of an object and (ii) physical displaying of a 3D image resulting from interference of two object (slightly different) wavefronts registered at the SA double exposure hologram. The capture and display processes are analyzed and implemented. The applicability of both numerical and experimental approach to SA DEDH for testing engineering objects is discussed.

  5. Physical Mechanisms and Scaling Laws of K-Shell Double Photoionization

    SciTech Connect

    Hoszowska, J.; Dousse, J.-Cl.; Berset, M.; Cao, W.; Fennane, K.; Kayser, Y.; Szlachetko, J.; Szlachetko, M.; Kheifets, A. K.; Bray, I.; Kavcic, M.

    2009-02-20

    We report on the photon energy dependence of the K-shell double photoionization (DPI) of Mg, Al, and Si. The DPI cross sections were derived from high-resolution measurements of x-ray spectra following the radiative decay of the K-shell double vacancy states. Our data evince the relative importance of the final-state electron-electron interaction to the DPI. By comparing the double-to-single K-shell photoionization cross-section ratios for neutral atoms with convergent close-coupling calculations for He-like ions, the effect of outer shell electrons on the K-shell DPI process is assessed. Universal scaling of the DPI cross sections with the effective nuclear charge for neutral atoms is revealed.

  6. The mechanism of double-exponential growth in hyper-inflation

    NASA Astrophysics Data System (ADS)

    Mizuno, T.; Takayasu, M.; Takayasu, H.

    2002-05-01

    Analyzing historical data of price indices, we find an extraordinary growth phenomenon in several examples of hyper-inflation in which, price changes are approximated nicely by double-exponential functions of time. In order to explain such behavior we introduce the general coarse-graining technique in physics, the Monte Carlo renormalization group method, to the price dynamics. Starting from a microscopic stochastic equation describing dealers’ actions in open markets, we obtain a macroscopic noiseless equation of price consistent with the observation. The effect of auto-catalytic shortening of characteristic time caused by mob psychology is shown to be responsible for the double-exponential behavior.

  7. Ambient-temperature Conditioning as a Probe of Double-C Transformation Mechanisms in Pu-2.0 at. % Ga

    SciTech Connect

    Jeffries, J R; Blobaum, K M; Wall, M A; Schwartz, A J

    2008-04-02

    The gallium-stabilized Pu-2.0 at. % Ga alloy undergoes a partial or incomplete low-temperature martensitic transformation from the metastable {delta} phase to the gallium-containing, monoclinic {alpha}{prime} phase near -100 C. This transformation has been shown to occur isothermally and it displays anomalous double-C kinetics in a time-temperature-transformation (TTT) diagram, where two nose temperatures anchoring an upper- and lower-C describe minima in the time for the initiation of transformation. The underlying mechanisms responsible for the double-C behavior are currently unresolved, although recent experiments suggest that a conditioning treatment--wherein, following an anneal at 375 C, the sample is held at a sub-anneal temperature for a period of time--significantly influences the upper-C of the TTT diagram. As such, elucidating the effects of the conditioning treatment upon the {delta} {yields} {alpha}{prime} transformation can provide valuable insights into the fundamental mechanisms governing the double-C kinetics of the transition. Following a high-temperature anneal, a differential scanning calorimeter (DSC) was used to establish an optimal conditioning curve that depicts the amount of {alpha}{prime} formed during the transformation as a function of conditioning temperature for a specified time. With the optimal conditioning curve as a baseline, the DSC was used to explore the circumstances under which the effects of the conditioning treatment were destroyed, resulting in little or no transformation.

  8. Fabrication of double-aperture hololens imaging system: application to mechanics

    NASA Astrophysics Data System (ADS)

    Yadav, H. L.; Kumari, Neelam; Bhushan, Ravi; Mallick, Anshuman; Gupta, B. N.

    2004-06-01

    Duffy suggested the use of double-aperture imaging system for the measurement of in-plane displacement component. In this arrangement, twin apertures are placed symmetrically over the imaging lens. This imaging system is used in speckle metrology to measure component of displacement parallel to the line joining the two apertures. The imaging lens used in such configuration need not be diffraction limited over the entire lens aperture, but only over the two small areas encompassed by the two apertures. In present work, compact holographic lenses have been used to generate the two apertures of Duffy's double-aperture interferometer. This imaging system has been used in speckle metrology to measure crack mouth opening displacement (CMOD) in an aluminium beam specimen having central edge crack subjected to three point bending. Experimental results are in good agreement with theoretical predictions. Present experimental investigation reveals that compact holographic lenses can be used advantageously to generate apertures of double-aperture speckle interferometer for its use in the measurement of in-plane displacement component.

  9. Analysis of the double bounce scattering mechanism of buildings in VHR SAR data

    NASA Astrophysics Data System (ADS)

    Brunner, D.; Bruzzone, L.; Ferro, A.; Fortuny, J.; Lemoine, G.

    2008-10-01

    This paper presents a detailed experimental study on the behavior of the backscattering of buildings in very high resolution (VHR) synthetic aperture radar (SAR) images under varying conditions. The double bounce effect caused by the corner reflector between the front wall of the buildign and its surrounding ground area is an important characterist of the building in VHR SAR. Therefore, we focus on the analysis of the relation between the double bounce effect and the aspect angle of the building. The study is carried out in three phases: i)development of a laboratory experimental setup on a scaled building model under well-controlled conditions with a variety of viewing configurations; ii) validation of the results obtained from the laboratyr measurements with real VHR airborne SAR data; iii) comparison of the above mentioned results with the simulations obtained by two theoretical models derived from electromagnetic theory. The laboratory experiments were carried out at the European Microwave Signature Lab (EMSL) at the Joint Research Centre (JRC) of the European Commission (EC), whie the real airborne SAR images wer acquired by the RAMSES sensor and were processed in order to obtain simulations of COSMO-SkyMed satellite images. The analyses showed that the strength of the double bounce drops rapidly in the low aspect angle range, while it decreases moderately for larter angles.

  10. Multiagent model and mean field theory of complex auction dynamics

    NASA Astrophysics Data System (ADS)

    Chen, Qinghua; Huang, Zi-Gang; Wang, Yougui; Lai, Ying-Cheng

    2015-09-01

    Recent years have witnessed a growing interest in analyzing a variety of socio-economic phenomena using methods from statistical and nonlinear physics. We study a class of complex systems arising from economics, the lowest unique bid auction (LUBA) systems, which is a recently emerged class of online auction game systems. Through analyzing large, empirical data sets of LUBA, we identify a general feature of the bid price distribution: an inverted J-shaped function with exponential decay in the large bid price region. To account for the distribution, we propose a multi-agent model in which each agent bids stochastically in the field of winner’s attractiveness, and develop a theoretical framework to obtain analytic solutions of the model based on mean field analysis. The theory produces bid-price distributions that are in excellent agreement with those from the real data. Our model and theory capture the essential features of human behaviors in the competitive environment as exemplified by LUBA, and may provide significant quantitative insights into complex socio-economic phenomena.

  11. Determination of Constitutive Equation for Thermo-mechanical Processing of INCONEL 718 Through Double Multivariate Nonlinear Regression Analysis

    NASA Astrophysics Data System (ADS)

    Hussain, Mirza Zahid; Li, Fuguo; Wang, Jing; Yuan, Zhanwei; Li, Pan; Wu, Tao

    2015-07-01

    The present study comprises the determination of constitutive relationship for thermo-mechanical processing of INCONEL 718 through double multivariate nonlinear regression, a newly developed approach which not only considers the effect of strain, strain rate, and temperature on flow stress but also explains the interaction effect of these thermo-mechanical parameters on flow behavior of the alloy. Hot isothermal compression experiments were performed on Gleeble-3500 thermo-mechanical testing machine in the temperature range of 1153 to 1333 K within the strain rate range of 0.001 to 10 s-1. The deformation behavior of INCONEL 718 is analyzed and summarized by establishing the high temperature deformation constitutive equation. The calculated correlation coefficient ( R) and average absolute relative error ( AARE) underline the precision of proposed constitutive model.

  12. Use of a small palindrome genetic marker to investigate mechanisms of double-strand-break repair in mammalian cells.

    PubMed Central

    Li, J; Baker, M D

    2000-01-01

    We examined mechanisms of mammalian homologous recombination using a gene targeting assay in which the vector-borne region of homology to the chromosome bore small palindrome insertions that frequently escape mismatch repair when encompassed within heteroduplex DNA (hDNA). Our assay permitted the product(s) of each independent recombination event to be recovered for molecular analysis. The results revealed the following: (i) vector-borne double-strand break (DSB) processing usually did not yield a large double-strand gap (DSG); (ii) in 43% of the recombinants, the results were consistent with crossover at or near the DSB; and (iii) in the remaining recombinants, hDNA was an intermediate. The sectored (mixed) genotypes observed in 38% of the recombinants provided direct evidence for involvement of hDNA, while indirect evidence was obtained from the patterns of mismatch repair (MMR). Individual hDNA tracts were either long or short and asymmetric or symmetric on the one side of the DSB examined. Clonal analysis of the sectored recombinants revealed how vector-borne and chromosomal markers were linked in each strand of individual hDNA intermediates. As expected, vector-borne and chromosomal markers usually resided on opposite strands. However, in one recombinant, they were linked on the same strand. The results are discussed with particular reference to the double-strand-break repair (DSBR) model of recombination. PMID:10757769

  13. Importance of the recoil contribution in Two Step 2 mechanism for the electron impact double ionization process

    NASA Astrophysics Data System (ADS)

    Li, C.; Staicu Casagrande, E. M.; Lahmam-Bennani, A.

    2014-04-01

    The second order, Two-Step-2 (TS2) mechanism for electron impact double ionization (DI) of various targets at intermediate incident energy is investigated based on a kinematical analysis which assumes the DI to result from two successive (e,2e) single ionization (SI) events. The results show that under the present kinematics, the inclusion of the recoil scattering in each of these (e,2e)-SI steps (in previous studies only the binary scattering was considered) allows a more detailed understanding of the various peaks observed in the experimental angular distributions of the ejected electrons in both (e,3-1e) and (e,3e) experiments.

  14. From classical mechanics with doubled degrees of freedom to quantum field theory for nonconservative systems

    NASA Astrophysics Data System (ADS)

    Kuwahara, Y.; Nakamura, Y.; Yamanaka, Y.

    2013-12-01

    The 2×2-matrix structure of Green's functions is a common feature for the real-time formalisms of quantum field theory under thermal situations, such as the closed time path formalism and Thermo Field Dynamics (TFD). It has been believed to originate from quantum nature. Recently, Galley has proposed the Hamilton's principle with initial data for nonconservative classical systems, doubling each degree of freedom [1]. We show that the Galley's Hamilton formalism can be extended to quantum field and that the resulting theory is naturally identical with nonequilibrium TFD.

  15. Probable new type of reaction mechanism: Double. cap alpha. direct transfer process

    SciTech Connect

    Xu Shu-wei; Wu Guo-hua; Miao Rong-zhi; Han Fei

    1983-10-01

    It is assumed that /sup 8/Be consists of two ..cap alpha.. particles which are close to each other in configuration space. A spectroscopic density of /sup 8/Be cluster in the residue nuclei is then obtained, which is proportional to the square of the preformation probability of ..cap alpha.. particle at nuclear surface. Using the improved method of parametrization of EFR-DWBA overlap integral,/sup 1//sup en-dash//sup 2/ we calculate the double differential energy spectra and angular distributions of ..cap alpha.. particles for the reactions /sup 209/Bi (/sup 12/C, ..cap alpha..) /sup 217/Fr and extract the preformation probability of ..cap alpha.. particle at the surface of /sup 217/Fr nuclei from fitting the experimental data. The agreement within the range of calculation error between the preformation probabilities extracted from transfer reactions and ..cap alpha.. decay suggests that the reaction /sup 209/Bi(/sup 12/C, ..cap alpha..) /sup 217/Fr may be explained as a double ..cap alpha.. direct transfer process.

  16. 75 FR 74719 - Auction of VHF Commercial Television Station Construction Permits Scheduled for February 15, 2011...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... Auction 90 Comment Public Notice 75 FR 59747, September 23, 2010. i. Background 2. The Media Bureau... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS... 90 AGENCY: Federal Communications Commission. ACTION: Notice. SUMMARY: This document announces...

  17. 31 CFR 356.33 - Does the Treasury have any discretion in the auction process?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... discretion in the auction process? (a) We have the discretion to: (1) Accept, reject, or refuse to recognize... to modify the terms and conditions of new securities and to depart from the customary pattern...

  18. 31 CFR 356.33 - Does the Treasury have any discretion in the auction process?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... discretion in the auction process? (a) We have the discretion to: (1) Accept, reject, or refuse to recognize... to modify the terms and conditions of new securities and to depart from the customary pattern...

  19. 31 CFR 356.33 - Does the Treasury have any discretion in the auction process?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... discretion in the auction process? (a) We have the discretion to: (1) Accept, reject, or refuse to recognize... to modify the terms and conditions of new securities and to depart from the customary pattern...

  20. Bid distribution derived from consistent mixed strategy in lowest unique bid auction

    NASA Astrophysics Data System (ADS)

    Zhao, Yinan; Chen, Qinghua; Wang, Yougui

    2014-12-01

    The Lowest Unique Bid Auction (LUBA) booms recently through the Internet. A typical distribution pattern of bid price in this reverse auction has been found and needs to be interpreted. The distribution curve is a decreasing one whose slope has a close relationship with the number of agents participating in the auction. To explain this stylized fact, we develop a model assuming that agents prefer to bid on the price at which the probability of winning is higher. The bid distributions of actual auctions with the number of agents less than 200 can be fitted very well using the parameters for the value of items and the number of bids. When this number becomes larger, however, a deviation occurs between prediction and empirical data, which can be adjusted by introducing cognitive illusion of the bid number.

  1. Methotrexate intercalated layered double hydroxides with the mediation of surfactants: Mechanism exploration and bioassay study.

    PubMed

    Dai, Chao-Fan; Tian, De-Ying; Li, Shu-Ping; Li, Xiao-Dong

    2015-12-01

    Methotrexatum intercalated layered double hydroxides (MTX/LDHs) hybrids were synthesized by the co-precipitation method and three kinds of nonionic surfactants with different hydrocarbon chain lengths were used. The resulting hybrids were then characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy and transmission electron microscopy (TEM). XRD and FTIR investigations manifest the successful intercalation of MTX anions into the interlayer of LDHs. TEM graphs indicate that the morphology of the hybrids changes with the variation of the chain length of the surfactants, i.e., the particles synthesized using polyethylene glycol (PEG-7) present regular disc morphology with good monodispersity, while samples with the mediation of alkyl polyglycoside (APG-14) are heavily aggregated and samples with the addition of polyvinylpyrrolidone (PVP-10) exhibit irregular branches. Furthermore, the release and bioassay experiments show that monodisperse MTX/LDHs present good controlled-release and are more efficient in the suppression of the tumor cells. PMID:26354264

  2. Ions Transport and Adsorption Mechanisms in Porous Electrodes During Capacitive-Mixing Double Layer Expansion (CDLE)

    PubMed Central

    2012-01-01

    A model of the electro-diffusion of ions in porous electrodes is applied to analyze the dynamics of capacitive-mixing extraction of energy from salinity gradients with carbon porous electrodes. The complex time-evolution of the cell voltage observed in experiments is satisfactorily described. The asymmetry on the duration of the solution-change steps performed in open circuit is found to be due to the nonlinear voltage–concentration relationship of the electric double layers and to a current that redistributes the counterions along the depth of the electrode leading to nonuniform charge and salt adsorption. The validated model is an essential tool for the design and optimization of renewable energy extraction by this technique. PMID:24319518

  3. Mechanical coupled vibrations in an individual double-walled carbon nanotube

    NASA Astrophysics Data System (ADS)

    Boutahir, Mourad; Rahmani, Abdelhai; Chadli, Hassan; Rahmani, Abdelali

    2016-05-01

    In this paper we calculate the Raman spectra of different double-walled carbon nanotubes (DWCNTs) by using the spectral moments method. Using a convenient Lennard-Jones expression of the van der Waals intermolecular interaction between the inner and outer tubes, the optimized structures of DWCNT are derived. We found that the C-C bond length in DWCNT is depending on the metallic (M) or semiconducting (Sc) character of the inner and outer nanotubes. We show that the radial breathing-like modes (RBLM) of DWCNT are characterized by concerted inner and outer wall motions. Comparison with Raman spectra measurements is given. Contribution to the topical issue "Materials for Energy Harvesting, Conversion and Storage (ICOME 2015) - Elected submissions", edited by Jean-Michel Nunzi, Rachid Bennacer and Mohammed El Ganaoui

  4. Cryptanalysis and improvement of a secure quantum sealed-bid auction

    NASA Astrophysics Data System (ADS)

    Qin, Su-Juan; Gao, Fei; Wen, Qiao-Yan; Meng, Luo-Ming; Zhu, Fu-Chen

    2009-10-01

    The security of a secure quantum sealed-bid auction protocol using quantum secure direct communication [Mosayeb Naseri, Opt. Commun. 282 (2009) 1939] is analyzed. It is shown that this protocol is unfair as a malicious bidder can obtain others' bids without being found, and then he can optimize his bid to win the auction. Finally, a simple improvement to resist this attack is proposed.

  5. Analysis of a Receipt-Free Auction Protocol in the Applied Pi Calculus

    NASA Astrophysics Data System (ADS)

    Dong, Naipeng; Jonker, Hugo; Pang, Jun

    We formally study two privacy-type properties for online auction protocols: bidding-price-secrecy and receipt-freeness. These properties are formalised as observational equivalences in the applied π calculus. We analyse the receipt-free auction protocol by Abe and Suzuki. Bidding-price-secrecy of the protocol is verified using ProVerif, whereas receipt-freeness of the protocol is proved manually.

  6. A deployment mechanism for the double roll-out flexible solar array on the space telescope

    NASA Technical Reports Server (NTRS)

    Cawsey, T. R.

    1982-01-01

    A roll-out flexible array which provides more than 4 kW of power for the space telescope was developed. The Array is configured as two wings. The deployment mechanism for each wing is based on flight-proven FRUSA design. Modifications have been incorporated to accommodate an increase in size and mission requirements. The assembly and operation of the deployment mechanism are described together with environmental and functional tests results.

  7. Mechanical Properties of Double-Layer and Graded Composite Coatings of YSZ Obtained by Atmospheric Plasma Spraying

    NASA Astrophysics Data System (ADS)

    Carpio, Pablo; Rayón, Emilio; Salvador, María Dolores; Lusvarghi, Luca; Sánchez, Enrique

    2016-04-01

    Double-layer and graded composite coatings of yttria-stabilized zirconia were sprayed on metallic substrates by atmospheric plasma spray. The coating architecture was built up by combining two different feedstocks: one micro- and one nanostructured. Microstructural features and mechanical properties (hardness and elastic modulus) of the coatings were determined by FE-SEM microscopy and nanoindentation technique, respectively. Additional adherence and scratch tests were carried out in order to assess the failure mechanisms occurring between the layers comprising the composites. Microstructural inspection of the coatings confirms the two-zone microstructure. This bimodal microstructure which is exclusive of the layer obtained from the nanostructured feedstock negatively affects the mechanical properties of the whole composite. Nanoindentation tests suitably reproduce the evolution of mechanical properties through coatings thickness on the basis of the position and/or amount of nanostructured feedstock used in the depositing layer. Adhesion and scratch tests show the negative effect on the coating adhesion of layer obtained from the nanostructured feedstock when this layer is deposited on the bond coat. Thus, the poor integrity of this layer results in lower normal stresses required to delaminate the coating in the adhesion test as well as minor critical load registered by using the scratch test.

  8. Experimental investigation of combustion mechanisms of kerosene-fueled scramjet engines with double-cavity flameholders

    NASA Astrophysics Data System (ADS)

    Pan, Yu; Tan, Jian-Guo; Liang, Jian-Han; Liu, Wei-Dong; Wang, Zhen-Guo

    2011-12-01

    A scramjet combustor with double cavitybased flameholders was experimentally studied in a directconnected test bed with the inflow conditions of M = 2.64, P t = 1.84MPa, T t = 1 300 K. Successful ignition and self-sustained combustion with room temperature kerosene was achieved using pilot hydrogen, and kerosene was vertically injected into the combustor through 4×ϕ0.5mm holes mounted on the wall. For different equivalence ratios and different injection schemes with both tandem cavities and parallel cavities, flow fields were obtained and compared using a high speed camera and a Schlieren system. Results revealed that the combustor inside the flow field was greatly influenced by the cavity installation scheme, cavities in tandem easily to form a single side flame distribution, and cavities in parallel are more likely to form a joint flame, forming a choked combustion mode. The supersonic combustion flame was a kind of diffusion flame and there were two kinds of combustion modes. In the unchoked combustion mode, both subsonic and supersonic combustion regions existed. While in the choked mode, the combustion region was fully subsonic with strong shock propagating upstream. Results also showed that there was a balance point between the boundary separation and shock enhanced combustion, depending on the intensity of heat release.

  9. Measuring electrical and mechanical properties of red blood cells with a double optical tweezers

    NASA Astrophysics Data System (ADS)

    Fontes, Adriana; Fernandes, Heloise P.; Barjas-Castro, Maria L.; de Thomaz, André A.; Pozzo, Liliana d. Y.; Barbosa, Luiz C.; Cesar, Carlos L.

    2006-08-01

    The fluid lipid bilayer viscoelastic membrane of red blood cells (RBC) contains antigen glycolproteins and proteins which can interact with antibodies to cause cell agglutination. This is the basis of most of the immunohematologic tests in blood banks and the identification of the antibodies against the erythrocyte antigens is of fundamental importance for transfusional routines. The negative charges of the RBCs creates a repulsive electric (zeta) potential between the cells and prevents their aggregation in the blood stream. The first counterions cloud strongly binded moving together with the RBC is called the compact layer. This report proposes the use of a double optical tweezers for a new procedure for measuring: (1) the apparent membrane viscosity, (2) the cell adhesion, (3) the zeta potential and (4) the compact layer's size of the charges formed around the cell in the electrolytic solution. To measure the membrane viscosity we trapped silica beads strongly attached to agglutinated RBCs and measured the force to slide one RBC over the other as a function of the relative velocity. The RBC adhesion was measured by slowly displacing two RBCs apart until the disagglutination happens. The compact layer's size was measured using the force on the silica bead attached to a single RBC in response to an applied voltage and the zeta potential was obtained by measuring the terminal velocity after releasing the RBC from the optical trap at the last applied voltage. We believe that the methodology here proposed can improve the methods of diagnosis in blood banks.

  10. Heat transfer augmentation in double pipe heat exchanger using mechanical turbulators

    NASA Astrophysics Data System (ADS)

    Kamboj, Kushal; Singh, Gurjeet; Sharma, Rohit; Panchal, Dilbagh; Hira, Jaspreet

    2016-05-01

    The work presented here focuses on heat transfer augmentation by means of divergent-convergent spring turbulator (the enhancement device). Aim of the present work is to find such an optimum pitch at which the augmentation in heat transfer is maximum and the amount of power consumption is minimum, so that an economic design can be created with maximum thermal efficiency. So, the concept of pitch variation is introduced, which is defined as the horizontal distance between two consecutive turbulators. It describes that, the lesser is the pitch the more number of turbulators that can be inserted in inner pipe of double pipe heat exchanger, hence more will be the friction factor. This physics increases convective ability of the heat transfer process from the surface of inner pipe. There is a certain limit to which a pitch can be decreased, lesser the pitch the more the pressure drop and friction factor and hence the more will be the pumping power requirement to maintain a desired mass flow rate of hot water. Analysis of thermal factors such as Nusselts number, friction factor, with different pitches of divergent convergent spring turbulators of circular cross-section 15, 10, and 5 cm at Reynolds's number ranging between 9000 < Re < 40,000 is done graphically.

  11. Green Auctions and Reduction of Information Rents in Payments for Environmental Services: An Experimental Investigation in Sunan County, Northwestern China

    PubMed Central

    Deng, Xiaohong; Xu, Zhongmin

    2015-01-01

    Reducing information rents is an important task for government agencies wishing to purchase maximal environmental services with limited budgets. This paper reports on several green auction options for reducing information rents and improving the performance of the “Grain for Green” Payments for environmental services (PES) program implemented in northwestern China. In r experimental auctions and investigations, door-to-door interviews were conducted and bidding envelopes and survey questionnaires were used to determine the offers and the foregone profits of the participants. Three scenarios are analyzed in this paper: a uniform price auction, a discriminatory price auction, and an opportunity-cost system. The results show that compared to the uniform price auction system, the other auction systems can increase the cost-effectiveness of conservation contracting. Competitive bidding can reveal true opportunity costs and can reduce information rents extracted from the government by farmers using private information. The demographics and average bids of these auction types were also analyzed. “Perfect information” in the opportunity-cost offer system has the best performance but is very hard to implement in reality. The results of this research show that the auction is a valuable tool for purchasing conservation contracts in northwestern China, but that in the future, the performance of these auctions should be studied with relaxed model assumptions. PMID:25793263

  12. Green auctions and reduction of information rents in payments for environmental services: an experimental investigation in Sunan County, northwestern China.

    PubMed

    Deng, Xiaohong; Xu, Zhongmin

    2015-01-01

    Reducing information rents is an important task for government agencies wishing to purchase maximal environmental services with limited budgets. This paper reports on several green auction options for reducing information rents and improving the performance of the "Grain for Green" Payments for environmental services (PES) program implemented in northwestern China. In r experimental auctions and investigations, door-to-door interviews were conducted and bidding envelopes and survey questionnaires were used to determine the offers and the foregone profits of the participants. Three scenarios are analyzed in this paper: a uniform price auction, a discriminatory price auction, and an opportunity-cost system. The results show that compared to the uniform price auction system, the other auction systems can increase the cost-effectiveness of conservation contracting. Competitive bidding can reveal true opportunity costs and can reduce information rents extracted from the government by farmers using private information. The demographics and average bids of these auction types were also analyzed. "Perfect information" in the opportunity-cost offer system has the best performance but is very hard to implement in reality. The results of this research show that the auction is a valuable tool for purchasing conservation contracts in northwestern China, but that in the future, the performance of these auctions should be studied with relaxed model assumptions. PMID:25793263

  13. Development of Thread Rolled Anti-Loosening Bolts Based on the Double Thread Mechanism and a Performance Evaluation

    NASA Astrophysics Data System (ADS)

    Takemasu, Teruie; Miyahara, Hiroshi

    It has already been proven that bolt fasteners based on the double thread mechanism have an excellent anti-loosening performance. The purpose of this study is to establish a mass production method for these double thread bolts (DTBs) by thread rolling. The pitch ratio of the coarse thread and the fine thread of the target DTB is set as 2 to 1. A two-die roller with a plunge feed is employed as the rolling method due to its fine processing precision. The roller dies used in the experiments have special grooves on the external surface which follow the same outline as the thread profiles of the DTB. Using these special dies, the DTB can be successfully formed in the same process as single thread bolts. The deformation of a workpiece during rolling is examined, and the examination shows that the formed material smoothly fills the die grooves in each cross section. The rolled DTBs completely pass the loosening test with extremely severe vibration and impact, as specified in NAS3354. The tensile fatigue strength of the rolled DTB is about 100% greater than that of the cutting DTB.

  14. Double core of ozone valley over the Tibetan Plateau and its possible mechanisms

    NASA Astrophysics Data System (ADS)

    Guo, Dong; Su, Yucheng; Shi, Chunhua; Xu, Jianjun; Powell, Alfred M.

    2015-08-01

    In this study, the three-dimensional structure of the ozone valley (e.g. ozone depletion) over the Tibetan Plateau (TP) in summer (June-August) has been investigated using Microwave Limb Sounder (MLS) ozone (O3) data from 2005 to 2013. A double core structure of the ozone valley over the TP is found with one depletion center in upper stratosphere (10-2 hPa) named the upper core, and another depletion center, named the lower core, is observed in the upper troposphere/lower stratosphere (200-50 hPa). The analysis indicates that the zonal deviation of ozone O3* (O3*=O3-[O3], here [O3] is the zonal mean of O3) at the upper core is nearly -1 DU while its counterpart's deviation at the lower core is nearly -15 DU. Large scale atmospheric circulation and terrain effects play an important role in the ozone valley at the lower core. In contrast, photochemistry reactions of odd chlorine including chlorine atoms (Cl) and chlorine monoxide (ClO) dominate the ozone valley at the upper core. Based on the MLS products, support for a chemical driver at the upper core is based on: (1) the significant diurnal variability of ozone suggests possible photochemistry reactions impacting the ozone valley; (2) the positive center of the ClO zonal deviation (CLO*) and hydrogen chloride (HCl) zonal deviation (HCl*) are found at the bottom of the upper core, which means the higher odd chlorine may accelerate the ozone loss.

  15. Hydroxy double salts loaded with bioactive ions: Synthesis, intercalation mechanisms, and functional performance

    NASA Astrophysics Data System (ADS)

    Kaassis, Abdessamad Y. A.; Xu, Si-Min; Guan, Shanyue; Evans, David G.; Wei, Min; Williams, Gareth R.

    2016-06-01

    The intercalation of the anions of diclofenac (Dic), naproxen (Nap), and valproic acid (Val) into three hydroxy double salts (HDSs) has been explored in this work. Experiments were performed with [Co1.2Zn3.8(OH)8](NO3)2·2H2O (CoZn-NO3), [Ni2Zn3(OH)8](NO3)2·2H2O (NiZn-NO3) and [Zn5(OH)8](NO3)2·2H2O (Zn-NO3). It proved possible to intercalate diclofenac and naproxen into all three HDSs. In contrast, Val could be intercalated into CoZn-NO3 but when it was reacted with Zn-NO3 the HDS structure was destroyed, and the product comprised ZnO. Successful intercalation was verified by X-ray diffraction, IR spectroscopy, and elemental microanalysis. Molecular dynamics simulations showed the Dic and Nap ions to arrange themselves in an "X" shape in the interlayer space, forming a bilayer. Val was found to adopt a position with its aliphatic groups parallel to the HDS layer, again in a bilayer. In situ time resolved X-ray diffraction experiments revealed that intercalation of Dic and Nap into CoZn-NO3 and Zn-NO3 is mechanistically complex, with a number of intermediate phases observed. In contrast, the intercalation of all three guests into NiZn-NO3 and of Val into CoZn-NO3 are simple one step reactions proceeding directly from the starting material to the product. The HDS-drug composites were found to have sustained release profiles.

  16. Study of the negative ion extraction mechanism from a double-ion plasma in negative ion sources

    NASA Astrophysics Data System (ADS)

    Goto, I.; Miyamoto, K.; Nishioka, S.; Hatayama, A.

    2015-04-01

    We have developed a 2D3V-PIC model of the extraction region, aiming to clarify the basic extraction mechanism of H- ions from the double-ion plasma in H- negative ion sources. The result shows the same tendency of the H- ion density nH- as that observed in the experiments, i.e.,nH- in the upstream region away from the plasma meniscus (H- emitting surface) has been reduced by applying the extraction voltage. At the same time, relatively slow temporal oscillation of the electric potential compared with the electron plasma frequency has been observed in the extraction region. Results of the systematic study using a 1D3V-PIC model with the uniform magnetic field confirm the result that the electrostatic oscillation is identified to be lower hybrid wave. The effect of this oscillation on the H- transport will be studied in the future.

  17. Correlation of fragility with mechanical moduli in double-well potential for glass-forming liquid

    NASA Astrophysics Data System (ADS)

    Cao, Wan Qiang

    2012-02-01

    The shoving model and the Vogel-Fulcher relation are employed to derive correlation of the fragility with the mechanical moduli for glass-forming simple liquids. The result shows that a liquid with smaller fragility will have larger ratio of K∞/G∞ in dilute liquid system. Based on radial distribution function with the Lennard-Jones potential modified by the Gaussian potential with a second minimum, fragility of the supercooled simple liquid is derived from the correlation between viscosity and shear modulus via configurational entropy. The results demonstrate that the fragility is determined by two parts: thermodynamic components and mechanical moduli. For a weak Gaussian potential liquid, the fragility is proportional to the Tg, while for a strong one, the fragility is inversely proportional to the Tg, and the Gaussian potential will increase fragility.

  18. DNA Double-Strand Breaks Induced by Cavitational Mechanical Effects of Ultrasound in Cancer Cell Lines

    PubMed Central

    Furusawa, Yukihiro; Fujiwara, Yoshisada; Campbell, Paul; Zhao, Qing-Li; Ogawa, Ryohei; Ali Hassan, Mariame; Tabuchi, Yoshiaki; Takasaki, Ichiro; Takahashi, Akihisa; Kondo, Takashi

    2012-01-01

    Ultrasonic technologies pervade the medical field: as a long established imaging modality in clinical diagnostics; and, with the emergence of targeted high intensity focused ultrasound, as a means of thermally ablating tumours. In parallel, the potential of [non-thermal] intermediate intensity ultrasound as a minimally invasive therapy is also being rigorously assessed. Here, induction of apoptosis in cancer cells has been observed, although definitive identification of the underlying mechanism has thus far remained elusive. A likely candidate process has been suggested to involve sonochemical activity, where reactive oxygen species (ROS) mediate the generation of DNA single-strand breaks. Here however, we provide compelling new evidence that strongly supports a purely mechanical mechanism. Moreover, by a combination of specific assays (neutral comet tail and staining for γH2AX foci formation) we demonstrate for the first time that US exposure at even moderate intensities exhibits genotoxic potential, through its facility to generate DNA damage across multiple cancer lines. Notably, colocalization assays highlight that ionizing radiation and ultrasound have distinctly different signatures to their respective γH2AX foci formation patterns, likely reflecting the different stress distributions that initiated damage formation. Furthermore, parallel immuno-blotting suggests that DNA-PKcs have a preferential role in the repair of ultrasound-induced damage. PMID:22235259

  19. Study of Electrical Conduction Mechanism of Organic Double-Layer Diode Using Electric Field Induced Optical Second Harmonic Generation Measurement.

    PubMed

    Nishi, Shohei; Taguchi, Dai; Manaka, Takaaki; Iwamoto, Mitsumasa

    2016-04-01

    By using electric field induced optical second harmonic generation (EFISHG) and current voltage (I-V) measurements, we studied the electrical transport mechanism of organic double-layer diodes with a structure of Au/N, N'-di-[(1-naphthyl)-N, N'-diphenyl]-(1,1'-biphenyl)-4,4'-diamine (a-NPD)/poly(methyl methacrylate) (PMMA)/indium zinc oxide (IZO). Here the α-NPD is a carrier transport layer and the PMMA is an electrical insulating layer. The current level was very low, but the I-V characteristics showed a rectifying behavior. The EFISHG measurement selectively and directly probed the electric field across the α-NPD layer, and showed that the electric field across the a-NPD layer is completely relaxed owing to the charge accumulation at the a-NPD/PMMA interface in the region V > 0, whereas the carrier accumulation was not significant in the region V < 0. On the basis of these experimental results, we proposed a model of the rectification. Further, by coupling the I-V characteristics with the EFISHG measurement, the I-V characteristics of the diodes were well converted into the current-electric field (I-E) characteristics of the α-NPD layer and the PMMA layer. The I-E characteristics suggested the Schottky-type conduction governs the carrier transport. We conclude that the I-V measurement coupled with the EFISHG measurement is very useful to study carrier transport mechanism of the organic double-layer diodes. PMID:27451633

  20. Nonsequential Double Ionization of Atoms in Strong Laser Field: Identifying the Mechanisms behind the Correlated-Electron Momentum Spectra

    NASA Astrophysics Data System (ADS)

    Ye, Difa; Fu, Libin; Liu, Jie

    Within the strong-field physics community, there has been increasing interest on nonsequential double ionization (NSDI) induced by electron-electron (e-e) correlation. A large variety of novel phenomena has been revealed in experiments during the past decades. However, the theoretical understanding and interpretation of this process is still far from being complete. The most accurate simulation, i.e. the exact solution of the time-dependent Schrödinger equation (TDSE) for two electrons in a laser field is computationally expensive. In order to overcome the difficulty, we proposed a feasible semiclassical model, in which we treat the tunneling ionization of the outmost electron quantum mechanically according to the ADK theory, sample the inner electron from microcanonical distribution and then evolve the two electrons with Newton's equations. With this model, we have successfully explained various NSDI phenomena, including the excessive DI yield, the energy spectra and angular distribution of photoelectrons. Very recently, it is adopted to reveal the physical mechanisms behind the fingerlike structure in the correlated electron momentum spectra, the unexpected correlation-anticorrelation transition close to the recollision threshold, and the anomalous NSDI of alkaline-earth-metal atoms in circularly polarized field. The obvious advantage of our model is that it gives time-resolved insights into the complex dynamics of NSDI, from the turn-on of the laser field to the final escape of the electrons, thus allowing us to disentangle and thoroughly analyze the underlying physical mechanisms.

  1. Double torsion fracture mechanics testing of shales under chemically reactive conditions

    NASA Astrophysics Data System (ADS)

    Chen, X.; Callahan, O. A.; Holder, J. T.; Olson, J. E.; Eichhubl, P.

    2015-12-01

    Fracture properties of shales is vital for applications such as shale and tight gas development, and seal performance of carbon storage reservoirs. We analyze the fracture behavior from samples of Marcellus, Woodford, and Mancos shales using double-torsion (DT) load relaxation fracture tests. The DT test allows the determination of mode-I fracture toughness (KIC), subcritical crack growth index (SCI), and the stress-intensity factor vs crack velocity (K-V) curves. Samples are tested at ambient air and aqueous conditions with variable ionic concentrations of NaCl and CaCl2, and temperatures up to 70 to determine the effects of chemical/environmental conditions on fracture. Under ambient air condition, KIC determined from DT tests is 1.51±0.32, 0.85±0.25, 1.08±0.17 MPam1/2 for Marcellus, Woodford, and Mancos shales, respectively. Tests under water showed considerable change of KIC compared to ambient condition, with 10.6% increase for Marcellus, 36.5% decrease for Woodford, and 6.7% decrease for Mancos shales. SCI under ambient air condition is between 56 and 80 for the shales tested. The presence of water results in a significant reduction of the SCI from 70% to 85% compared to air condition. Tests under chemically reactive solutions are currently being performed with temperature control. K-V curves under ambient air conditions are linear with stable SCI throughout the load-relaxation period. However, tests conducted under water result in an initial cracking period with SCI values comparable to ambient air tests, which then gradually transition into stable but significantly lower SCI values of 10-20. The non-linear K-V curves reveal that crack propagation in shales is initially limited by the transport of chemical agents due to their low permeability. Only after the initial cracking do interactions at the crack tip lead to cracking controlled by faster stress corrosion reactions. The decrease of SCI in water indicates higher crack propagation velocity due to

  2. Identification of shareholder ethics and responsibilities in online reverse auctions for construction projects.

    PubMed

    Hatipkarasulu, Yilmaz; Gill, James H

    2004-04-01

    The increasing number of companies providing internet services and auction tools helped popularize the online reverse auction trend for purchasing commodities and services in the last decade. As a result, a number of owners, both public and private, accepted the online reverse auctions as the bidding technique for their construction projects. Owners, while trying to minimize their costs for construction projects, are also required to address their ethical responsibilities to the shareholders. In the case of online reverse auctions for construction projects, the ethical issues involved in the bidding technique directly reflects on the owner's ethical and social responsibilities to their shareholders. The goal of this paper is to identify the shareholder ethics and responsibilities in online reverse auctions for construction projects by analyzing the ethical issues for the parties involved in the process. The identification of the ethical issues and responsibilities requires clear definition and understanding of professional ethics and the roles of the involved parties. In this paper, first, the concept of professional ethics and social responsibility is described in a general form. To illustrate the ethical issues and responsibilities, a sample case of bidding for a construction project using online reverse auction techniques is presented in which the shareholders were actively involved in questioning the ethical issues. The issues involved in the bidding process and their reflection on the shareholder responsibilities are described and analyzed for each stage of the process. A brief discussion of the overall process is also included to address the general ethical issues involved in online reverse auctions. PMID:15152854

  3. Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections

    PubMed Central

    Hodgson, Kelly; Morris, Jodie; Bridson, Tahnee; Govan, Brenda; Rush, Catherine; Ketheesan, Natkunam

    2015-01-01

    Diabetes has been recognized as an important risk factor for a variety of intracellular bacterial infections, but research into the dysregulated immune mechanisms contributing to the impaired host–pathogen interactions is in its infancy. Diabetes is characterized by a chronic state of low-grade inflammation due to activation of pro-inflammatory mediators and increased formation of advanced glycation end products. Increased oxidative stress also exacerbates the chronic inflammatory processes observed in diabetes. The reduced phagocytic and antibacterial activity of neutrophils and macrophages provides an intracellular niche for the pathogen to replicate. Phagocytic and antibacterial dysfunction may be mediated directly through altered glucose metabolism and oxidative stress. Furthermore, impaired activation of natural killer cells contributes to decreased levels of interferon-γ, required for promoting macrophage antibacterial mechanisms. Together with impaired dendritic cell function, this impedes timely activation of adaptive immune responses. Increased intracellular oxidation of antigen-presenting cells in individuals with diabetes alters the cytokine profile generated and the subsequent balance of T-cell immunity. The establishment of acute intracellular bacterial infections in the diabetic host is associated with impaired T-cell-mediated immune responses. Concomitant to the greater intracellular bacterial burden and potential cumulative effect of chronic inflammatory processes, late hyper-inflammatory cytokine responses are often observed in individuals with diabetes, contributing to systemic pathology. The convergence of intracellular bacterial infections and diabetes poses new challenges for immunologists, providing the impetus for multidisciplinary research. PMID:25262977

  4. A preconscious neural mechanism of hypnotically altered colors: a double case study.

    PubMed

    Koivisto, Mika; Kirjanen, Svetlana; Revonsuo, Antti; Kallio, Sakari

    2013-01-01

    Hypnotic suggestions may change the perceived color of objects. Given that chromatic stimulus information is processed rapidly and automatically by the visual system, how can hypnotic suggestions affect perceived colors in a seemingly immediate fashion? We studied the mechanisms of such color alterations by measuring electroencephalography in two highly suggestible participants as they perceived briefly presented visual shapes under posthypnotic color alternation suggestions such as "all the squares are blue". One participant consistently reported seeing the suggested colors. Her reports correlated with enhanced evoked upper beta-band activity (22 Hz) 70-120 ms after stimulus in response to the shapes mentioned in the suggestion. This effect was not observed in a control condition where the participants merely tried to simulate the effects of the suggestion on behavior. The second participant neither reported color alterations nor showed the evoked beta activity, although her subjective experience and event-related potentials were changed by the suggestions. The results indicate a preconscious mechanism that first compares early visual input with a memory representation of the suggestion and consequently triggers the color alteration process in response to the objects specified by the suggestion. Conscious color experience is not purely the result of bottom-up processing but it can be modulated, at least in some individuals, by top-down factors such as hypnotic suggestions. PMID:23940663

  5. Double seesaw mechanism in a left-right symmetric model with TeV neutrinos

    SciTech Connect

    Almeida, F. M. L. Jr. de; Coutinho, Y. A.; Simoes, J. A. Martins; Ramalho, A. J.; Pinto, L. Ribeiro; Wulck, S.; Vale, M. A. B. do

    2010-03-01

    A left-right symmetric model is discussed with new mirror fermions and a Higgs sector with two doublets and neutral scalar singlets. The seesaw mechanism is generalized, including not only neutrino masses but also charged fermion masses. The spectrum of heavy neutrinos presents a second seesaw mass matrix and has neutrinos masses naturally in the TeV region. The model has very clear signatures for the new neutral vector gauge bosons. Two classes of models are discussed. New mirror neutrinos can be very light and a new Z{sup '} can be discriminated from other models by a very high invisible branching fraction. The other possibility is that mirror neutrinos can have masses naturally in the TeV region and can be produced through Z{sup '} decays into heavy neutrino pairs. Signatures and production processes for the model at the LHC energy are also presented.

  6. Structural Mechanism of Allosteric Activity Regulation in a Ribonucleotide Reductase with Double ATP Cones.

    PubMed

    Johansson, Renzo; Jonna, Venkateswara Rao; Kumar, Rohit; Nayeri, Niloofar; Lundin, Daniel; Sjöberg, Britt-Marie; Hofer, Anders; Logan, Derek T

    2016-06-01

    Ribonucleotide reductases (RNRs) reduce ribonucleotides to deoxyribonucleotides. Their overall activity is stimulated by ATP and downregulated by dATP via a genetically mobile ATP cone domain mediating the formation of oligomeric complexes with varying quaternary structures. The crystal structure and solution X-ray scattering data of a novel dATP-induced homotetramer of the Pseudomonas aeruginosa class I RNR reveal the structural bases for its unique properties, namely one ATP cone that binds two dATP molecules and a second one that is non-functional, binding no nucleotides. Mutations in the observed tetramer interface ablate oligomerization and dATP-induced inhibition but not the ability to bind dATP. Sequence analysis shows that the novel type of ATP cone may be widespread in RNRs. The present study supports a scenario in which diverse mechanisms for allosteric activity regulation are gained and lost through acquisition and evolutionary erosion of different types of ATP cone. PMID:27133024

  7. Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formation

    PubMed Central

    Fishburn, James; Tomko, Eric; Galburt, Eric; Hahn, Steven

    2015-01-01

    Formation of the RNA polymerase II (Pol II) open complex (OC) requires DNA unwinding mediated by the transcription factor TFIIH helicase-related subunit XPB/Ssl2. Because XPB/Ssl2 binds DNA downstream from the location of DNA unwinding, it cannot function using a conventional helicase mechanism. Here we show that yeast TFIIH contains an Ssl2-dependent double-stranded DNA translocase activity. Ssl2 tracks along one DNA strand in the 5′ → 3′ direction, implying it uses the nontemplate promoter strand to reel downstream DNA into the Pol II cleft, creating torsional strain and leading to DNA unwinding. Analysis of the Ssl2 and DNA-dependent ATPase activity of TFIIH suggests that Ssl2 has a processivity of approximately one DNA turn, consistent with the length of DNA unwound during transcription initiation. Our results can explain why maintaining the OC requires continuous ATP hydrolysis and the function of TFIIH in promoter escape. Our results also suggest that XPB/Ssl2 uses this translocase mechanism during DNA repair rather than physically wedging open damaged DNA. PMID:25775526

  8. Electrical transport mechanism in a newly synthesized rare earth double perovskite oxide Sr2CeTaO6

    NASA Astrophysics Data System (ADS)

    Bharti, Chandrahas; Chanda, Sadhan; Sinha, T. P.

    2013-01-01

    A rare earth double perovskite oxide strontium cerium tantalate, Sr2CeTaO6 (SCT) is synthesized by the solid state reaction technique for the first time. The determination of lattice parameters and the identification of phase are carried out by the Rietveld refinement method (RRM) using the Fullprof program in the space group P21/n (C52h). A structure of SCT is obtained from RRM. The bond angle and bond length are calculated and listed in Table 1 for SCT. A small amount of impurity of CeO2 is found in the refinement with space group Fm3m. The scanning electron micrograph shows the average grain size ∼2 μm. The ac electrical property is investigated in the temperature range from 303 to 703 K and in the frequency range from 0.1 kHz to 1 MHz using impedance spectroscopy. The relaxation mechanism of SCT is explained in detail by fitting experimental impedance and electric modulus data with the modified Debye (Cole-Cole) model. The frequency-dependent electrical data are analyzed in the framework of the conductivity and modulus formalisms. The σac data are fitted with Jonscher's universal power law. The dc conductivity (σdc) (calculated from σac) follows an Arrhenius law with the estimated conduction activation energy =0.78 eV. The scaling behavior of imaginary part of electrical impedance (Z″) shows that the relaxation describes the same mechanism at various temperatures.

  9. PicoNewton-Millisecond Force Steps Reveal the Transition Kinetics and Mechanism of the Double-Stranded DNA Elongation

    PubMed Central

    Bianco, Pasquale; Bongini, Lorenzo; Melli, Luca; Dolfi, Mario; Lombardi, Vincenzo

    2011-01-01

    We study the kinetics of the overstretching transition in λ-phage double-stranded (ds) DNA from the basic conformation (B state) to the 1.7-times longer and partially unwound conformation (S state), using the dual-laser optical tweezers under force-clamp conditions at 25°C. The unprecedented resolution of our piezo servo-system, which can impose millisecond force steps of 0.5–2 pN, reveals the exponential character of the elongation kinetics and allows us to test the two-state nature of the B-S transition mechanism. By analyzing the load-dependence of the rate constant of the elongation, we find that the elementary elongation step is 5.85 nm, indicating a cooperativity of ∼25 basepairs. This mechanism increases the free energy for the elementary reaction to ∼94 kBT, accounting for the stability of the basic conformation of DNA, and explains why ds-DNA can remain in equilibrium as it overstretches. PMID:21843477

  10. Quantum Mechanical Effects on the Threshold Voltage of Double-Gate Metal-Oxide-Semiconductor Field-Effect Transistors

    NASA Astrophysics Data System (ADS)

    Hu, Guang-Xi; Liu, Ran; Qiu, Zhi-Jun; Wang, Ling-Li; Tang, Ting-Ao

    2010-03-01

    A model for a metal-oxide-semiconductor field-effect transistor (MOSFET) with a double gate (DG) is developed. Quantum mechanical effects on the threshold voltage (VTH) are modeled and investigated analytically. The analytic model shows how VTH is increased with quantum mechanical effect. The model is applicable to both symmetric DG (SDG) and asymmetric DG (ADG) nMOSFETs, and is also applicable to both doped and undoped DG nMOSFETs. The analytic results are verified by comparing with the results obtained from simulations using Schred, and good agreement is observed. The VTH of an ADG nMOSFET will shift more than that of an SDG nMOSFET, and the VTH of a DG transistor with (110)-silicon (Si) orientation will shift more than that of a DG transistor with (100)-Si orientation. When the silicon thickness tsi < 3 nm, the VTH shift will be significant, and one should be careful in the use of an extremely thin silicon body. When the body doping density (NA) is not high (<1018 cm-3), the VTH shift is almost the same for different NA. When NA > 1018 cm-3, the higher the NA, the more the VTH shift.

  11. Double-Barrier mechanism for chromium immobilization: A quantitative study of crystallization and leachability.

    PubMed

    Liao, Changzhong; Tang, Yuanyuan; Liu, Chengshuai; Shih, Kaimin; Li, Fangbai

    2016-07-01

    Glass-ceramics are well known for the excellent combination properties provided by their components, a glassy matrix and crystalline phases, and have promising applications in the immobilization and detoxification of solid waste containing toxic metals. Glass-ceramic products were successfully synthesized in CaO-MgO-SiO2-Al2O3 -Cr2O3 system. Two key measures--partitioning ratio of Cr in the spinel and Cr leaching ratio--were used to investigate the mechanism of Cr immobilization in the glass-ceramic products. The results of powder X-ray diffraction revealed that both spinel and diopside were major crystalline phases in the products. The value of x in the MgCr(x)Al(2-x)O4 spinel was highly related to the amount of Cr2O3 added to the glass-ceramic system. As Cr2O3 content increased, the proportion of spinel phase increased, while that of glass phase decreased. The partitioning ratio of Cr in spinel phase was about 70% for 2 wt.% Cr2O3, and increased to 90% when loaded with 10 wt.% of Cr2O3. According to the results of the prolonged toxicity characteristic leaching procedure, the Cr leaching ratio decreased with the increase of Cr partitioning ratio into the spinel phase. The findings of this study clearly indicate that glass-ceramic formed by spinel structure and residual glass successfully immobilized Cr. PMID:26994355

  12. Reversible and Irreversible Mechanical Damaging of Large Double-Stranded DNA upon Electrospraying.

    PubMed

    Shlyapnikov, Yuri M; Shlyapnikova, Elena A; Morozov, Victor N

    2016-07-19

    Electrohydrodynamic spraying (or electrospaying, ES) of DNA solutions is an attractive technique for applications in mass spectrometry, in microarray fabrication, and in generation of DNA nanoaerosols. Here we report how ES affects DNA structure and evaluate possible ways to reduce DNA damage upon ES. It is shown that under any ES conditions, linear λ-phage DNA is subjected to intensive rupture producing a mixture of fragments. In addition to such fragmentation, notable reversible changes in the DNA structure were revealed by a slight increase in DNA electrophoretic mobility. The degree of fragmentation was shown to decrease with decreased DNA length and with increased flow rate through the ES capillary. Fragments shorter than 5 kbp did not show any notable damage upon ES. Both experimental data and theoretical estimations of the forces acting on DNA during ES indicate that DNA is damaged by mechanical forces, and the damage takes place in the vicinity of the Taylor cone tip, presumably due to the high shear stress or/and viscous drag forces operating there. Condensation of λ-DNA with hexamminecobalt(III) ions completely protected it from any damage upon ES. PMID:27306261

  13. Competitive bidding for health insurance contracts: lessons from the online HMO auctions.

    PubMed

    Gupta, Alok; Parente, Stephen T; Sanyal, Pallab

    2012-12-01

    Healthcare is an important social and economic component of modern society, and the effective use of information technology in this industry is critical to its success. As health insurance premiums continue to rise, competitive bidding may be useful in generating stronger price competition and lower premium costs for employers and possibly, government agencies. In this paper, we assess an endeavor by several Fortune 500 companies to reduce healthcare procurement costs for their employees by having HMOs compete in open electronic auctions. Although the auctions were successful in generating significant cost savings for the companies in the first year, i.e., 1999, they failed to replicate the success and were eventually discontinued after two more years. Over the past decade since the failed auction experiment, effective utilization of information technologies have led to significant advances in the design of complex electronic markets. Using this knowledge, and data from the auctions, we point out several shortcomings of the auction design that, we believe, led to the discontinuation of the market after three years. Based on our analysis, we propose several actionable recommendations that policy makers can use to design a sustainable electronic market for procuring health insurance. PMID:23224233

  14. 76 FR 76174 - Request for Information on the State of the Offshore Renewable Energy Industry-Auction Format...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ...BOEM invites public comment on a proposed set of auction formats which may be used to issue commercial renewable energy leases on the Outer Continental Shelf (OCS). BOEM is examining several auction formats, each designed to efficiently issue renewable energy leases to those who value them most and are best positioned to develop them, while also ensuring that the government receives a fair......

  15. 7 CFR 29.75a - Display of burley tobacco on auction warehouse floors in designated markets.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Display of burley tobacco on auction warehouse floors... COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS TOBACCO INSPECTION Regulations Mandatory Inspection § 29.75a Display of burley tobacco on auction warehouse floors in designated markets. (a)(1) Each...

  16. 7 CFR 29.75a - Display of burley tobacco on auction warehouse floors in designated markets.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Display of burley tobacco on auction warehouse floors... COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS TOBACCO INSPECTION Regulations Mandatory Inspection § 29.75a Display of burley tobacco on auction warehouse floors in designated markets. (a)(1) Each...

  17. 7 CFR 29.75b - Display of baled flue-cured tobacco on auction warehouse floors in designated markets.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Display of baled flue-cured tobacco on auction... AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS TOBACCO INSPECTION Regulations Mandatory Inspection § 29.75b Display of baled flue-cured tobacco on auction warehouse floors in designated...

  18. 7 CFR 29.75b - Display of baled flue-cured tobacco on auction warehouse floors in designated markets.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Display of baled flue-cured tobacco on auction... AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS TOBACCO INSPECTION Regulations Mandatory Inspection § 29.75b Display of baled flue-cured tobacco on auction warehouse floors in designated...

  19. 77 FR 60690 - Auction of FM Broadcast Construction Permits Scheduled for March 26, 2013; Comment Sought on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ... Competitive Bidding Procedures for Auction 94 AGENCY: Federal Communications Commission. ACTION: Notice... commence on March 26, 2013. This document also seeks comment on competitive bidding procedures for Auction... that FM allotment will be awarded by competitive bidding procedures. Once mutual exclusivity exists...

  20. 76 FR 1158 - Auction of 700 MHz Band Licenses Scheduled for July 19, 2011; Comment Sought on Competitive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... COMMISSION Auction of 700 MHz Band Licenses Scheduled for July 19, 2011; Comment Sought on Competitive... comment on competitive bidding procedures for Auction 92. DATES: Comments are due on or before January 12... the fair and efficient conduct of competitive bidding. In such cases, the Bureau, in its...

  1. 78 FR 11179 - Auction of Lower and Upper Paging Bands Licenses Scheduled for July 16, 2013; Comment Sought on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... Competitive Bidding Procedures for Auction 95 AGENCY: Federal Communications Commission. ACTION: Notice... July 16, 2013. This document also seeks comment on competitive bidding procedures for Auction 95. DATES... any other reason that affects the fair and efficient conduct of competitive bidding. The Bureau...

  2. 75 FR 61752 - Auction of FM Broadcast Construction Permits Scheduled for March 29, 2011; Comment Sought on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... Competitive Bidding Procedures for Auction 91 AGENCY: Federal Communications Commission. ACTION: Notice... March 29, 2011 (Auction 91). This document also seeks comment on competitive bidding procedures for... the construction permit for that FM allotment will be awarded by competitive bidding procedures....

  3. 78 FR 21355 - Tribal Mobility Fund Phase I Auction Scheduled for October 24, 2013; Comment Sought on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ..., 76 FR 73830, November 29, 2011 and 76 FR 81562, December 28, 2011. Auction 902 will award one-time... Mobility Fund Phase I, 77 FR 14012. Petitions for designation as an ETC should be filed in WC Docket No. 09... COMMISSION Tribal Mobility Fund Phase I Auction Scheduled for October 24, 2013; Comment Sought on...

  4. 77 FR 11115 - Mobility Fund Phase I Auction Limited Extension of Deadlines for Comments and Reply Comments on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... released the Auction 901 Comment Public Notice, 77 FR 7152, February 10, 2012, which seeks comment on... Commission in the USF/ICC Transformation Order, 76 FR 73830, November 29, 2011 and 76 FR 81562, December 28... COMMISSION Mobility Fund Phase I Auction Limited Extension of Deadlines for Comments and Reply Comments...

  5. 47 CFR 27.1213 - Designated entity provisions for BRS in Commission auctions commencing prior to January 1, 2004.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., 2004 for BTA service areas are eligible for special incentives in the auction process. See 47 CFR 1... entity will have both de facto and de jure control of the entity. See 47 CFR 1.2110(i). (g) Records... authorizations awarded in the Commission BRS auctions commencing prior to January 1, 2004. (f)...

  6. Electronic Reverse Auctions: Integrating an E-Sourcing Tool into a Sales and Purchasing Cross-Course Negotiation Project

    ERIC Educational Resources Information Center

    Williams, Jacqueline A.; Dobie, Kathryn

    2011-01-01

    Electronic reverse auctions are increasingly being used by firms to improve firm financial and operational performance. The described teaching innovation serves as a model for introducing electronic reverse auctions as a central element in a comprehensive negotiation exercise involving sales management and purchasing management students. Results…

  7. 75 FR 56533 - Wireless Telecommunications Bureau Postpones Auction of 218-219 MHz Service and Phase II 220 MHz...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ... COMMISSION Wireless Telecommunications Bureau Postpones Auction of 218-219 MHz Service and Phase II 220 MHz... document announces the postponement of Auction 89. FOR FURTHER INFORMATION CONTACT: Wireless... related documents are also available on the Internet at the Commission's Web site:...

  8. 7 CFR 29.75b - Display of baled flue-cured tobacco on auction warehouse floors in designated markets.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... warehouse floors in designated markets. 29.75b Section 29.75b Agriculture Regulations of the Department of... Inspection § 29.75b Display of baled flue-cured tobacco on auction warehouse floors in designated markets. Each lot of baled flue-cured tobacco displayed for sale on auction warehouse floors shall have...

  9. Physical contact influences how much people pay at celebrity auctions.

    PubMed

    Newman, George E; Bloom, Paul

    2014-03-11

    Contagion is a form of magical thinking in which people believe that a person's immaterial qualities or essence can be transferred to an object through physical contact. Here we investigate how a belief in contagion influences the sale of celebrity memorabilia. Using data from three high-profile estate auctions, we find that people's expectations about the amount of physical contact between the object and the celebrity positively predicts the final bids for items that belonged to well-liked individuals (e.g., John F. Kennedy) and negatively predicts final bids for items that belonged to disliked individuals (e.g., Bernard Madoff). A follow-up experiment further suggests that these effects are driven by contagion beliefs: when asked to bid on a sweater owned by a well-liked celebrity, participants report that they would pay substantially less if it was sterilized before they received it. However, sterilization increases the amount they would pay for a sweater owned by a disliked celebrity. These studies suggest that magical thinking may still have effects in contemporary Western societies and they provide some unique demonstrations of contagion effects on real-world purchase decisions. PMID:24567388

  10. Physical contact influences how much people pay at celebrity auctions

    PubMed Central

    Newman, George E.; Bloom, Paul

    2014-01-01

    Contagion is a form of magical thinking in which people believe that a person’s immaterial qualities or essence can be transferred to an object through physical contact. Here we investigate how a belief in contagion influences the sale of celebrity memorabilia. Using data from three high-profile estate auctions, we find that people’s expectations about the amount of physical contact between the object and the celebrity positively predicts the final bids for items that belonged to well-liked individuals (e.g., John F. Kennedy) and negatively predicts final bids for items that belonged to disliked individuals (e.g., Bernard Madoff). A follow-up experiment further suggests that these effects are driven by contagion beliefs: when asked to bid on a sweater owned by a well-liked celebrity, participants report that they would pay substantially less if it was sterilized before they received it. However, sterilization increases the amount they would pay for a sweater owned by a disliked celebrity. These studies suggest that magical thinking may still have effects in contemporary Western societies and they provide some unique demonstrations of contagion effects on real-world purchase decisions. PMID:24567388

  11. Bidding process in online auctions and winning strategy: Rate equation approach

    NASA Astrophysics Data System (ADS)

    Yang, I.; Kahng, B.

    2006-06-01

    Online auctions have expanded rapidly over the last decade and have become a fascinating new type of business or commercial transaction in this digital era. Here we introduce a master equation for the bidding process that takes place in online auctions. We find that the number of distinct bidders who bid k times up to the t th bidding progresses, called the k -frequent bidder, seems to scale as nk(t)˜tk-2.4 . The successfully transmitted bidding rate by the k -frequent bidder is likely to scale as qk(t)˜k-1.4 , independent of t for large t . This theoretical prediction is close to empirical data. These results imply that bidding at the last moment is a rational and effective strategy to win in an eBay auction.

  12. Spiral of Hatred: Social Effects in Buyer-Seller Cross-Comments Left on Internet Auctions

    NASA Astrophysics Data System (ADS)

    Nielek, Radoslaw; Wawer, Aleksander; Wierzbicki, Adam

    An auction platform is a dynamic environment where a rich variety of social effects can be observed. Most of those effects remain unnoticed or even hidden to ordinary users. The in-depth studies of such effects should allow us to identify and understand the key factors influencing users’ behaviour. The material collected from the biggest Polish auction house has been analyzed. NLP algorithms were applied to extract sentiment-related content from collected comments. Emotional distance between negative, neutral and positive comments has been calculated. The obtained results confirm the existence of the spiral-of-hatred effect but also indicate that much more complex patterns of mutual relations between sellers and buyers exist. The last section contains a several suggestions which can prove useful to improve trustworthiness of users’ reports and security of an auction platform in general.

  13. Bidding process in online auctions and winning strategy: Rate equation approach.

    PubMed

    Yang, I; Kahng, B

    2006-06-01

    Online auctions have expanded rapidly over the last decade and have become a fascinating new type of business or commercial transaction in this digital era. Here we introduce a master equation for the bidding process that takes place in online auctions. We find that the number of distinct bidders who bid k times up to the tth bidding progresses, called the k-frequent bidder, seems to scale as n(k)(t) approximately tk(-2.4). The successfully transmitted bidding rate by the k-frequent bidder is likely to scale as q(k)(t) approximately k(-1.4), independent of t for large t. This theoretical prediction is close to empirical data. These results imply that bidding at the last moment is a rational and effective strategy to win in an eBay auction. PMID:16907028

  14. Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS

    PubMed Central

    Hanley, Claire J.; Tommerdahl, Mark; McGonigle, David J.

    2015-01-01

    The neuromodulation technique transcranial direct current stimulation (tDCS) is thought to produce its effects on behavior by altering cortical excitability. Although the mechanisms underlying the observed effects are thought to rely on the balance of excitatory and inhibitory neurotransmission, the physiological principles of the technique are not completely understood. In this study, we examine the influence of tDCS on vibrotactile adaptation, using a simple amplitude discrimination paradigm that has been shown to exhibit modifications in performance due to changes in inhibitory neurotransmission. Double-blind tDCS (Anodal/Sham) of 1 mA was delivered for 600 s to electrodes positioned in a somatosensory/contralateral orbit montage. Stimulation was applied as part of a pre/post design, between blocks of the behavioral tasks. In accordance with previous work, results obtained before the application of tDCS indicated that amplitude discrimination thresholds were significantly worsened during adaptation trials, compared to those achieved at baseline. However, tDCS failed to modify amplitude discrimination performance. Using a Bayesian approach, this finding was revealed to constitute substantial evidence for the null hypothesis. The failure of DC stimulation to alter vibrotactile adaptation thresholds is discussed in the context of several factors that may have confounded the induction of changes in cortical plasticity. PMID:26500499

  15. Study of the negative ion extraction mechanism from a double-ion plasma in negative ion sources

    SciTech Connect

    Goto, I.; Nishioka, S.; Hatayama, A.; Miyamoto, K.

    2015-04-08

    We have developed a 2D3V-PIC model of the extraction region, aiming to clarify the basic extraction mechanism of H{sup −} ions from the double-ion plasma in H{sup −} negative ion sources. The result shows the same tendency of the H{sup −} ion density n{sub H{sup −}} as that observed in the experiments, i.e.,n{sub H{sup −}} in the upstream region away from the plasma meniscus (H{sup −} emitting surface) has been reduced by applying the extraction voltage. At the same time, relatively slow temporal oscillation of the electric potential compared with the electron plasma frequency has been observed in the extraction region. Results of the systematic study using a 1D3V-PIC model with the uniform magnetic field confirm the result that the electrostatic oscillation is identified to be lower hybrid wave. The effect of this oscillation on the H{sup −} transport will be studied in the future.

  16. Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms

    PubMed Central

    Kostyrko, Kaja; Mermod, Nicolas

    2016-01-01

    DNA double stranded breaks (DSBs) are one of the most deleterious types of DNA lesions. The main pathways responsible for repairing these breaks in eukaryotic cells are homologous recombination (HR) and non-homologous end-joining (NHEJ). However, a third group of still poorly characterized DSB repair pathways, collectively termed microhomology-mediated end-joining (MMEJ), relies on short homologies for the end-joining process. Here, we constructed GFP reporter assays to characterize and distinguish MMEJ variant pathways, namely the simple MMEJ and the DNA synthesis-dependent (SD)-MMEJ mechanisms. Transfection of these assay vectors in Chinese hamster ovary (CHO) cells and characterization of the repaired DNA sequences indicated that while simple MMEJ is able to mediate relatively efficient DSB repair if longer microhomologies are present, the majority of DSBs were repaired using the highly error-prone SD-MMEJ pathway. To validate the involvement of DNA synthesis in the repair process, siRNA knock-down of different genes proposed to play a role in MMEJ were performed, revealing that the knock-down of DNA polymerase θ inhibited DNA end resection and repair through simple MMEJ, thus favoring the other repair pathway. Overall, we conclude that this approach provides a convenient assay to study MMEJ-related DNA repair pathways. PMID:26657630

  17. Scaling of volume to surface ratio and doubling time in growing unicellular organisms: Do cells appear quantum-mechanical systems?

    NASA Astrophysics Data System (ADS)

    Atanasov, Atanas Todorov

    2014-10-01

    The scaling of physical and biological characteristics of the living organisms is a basic method for searching of new biophysical laws. In series of previous studies the author showed that in Poikilotherms, Mammals and Aves, the volume to surface ratio V×S-1 (m) of organisms is proportional to their generation time Tgt(s) via growth rate v (m s-1): V×S-1 = vgr×Tr. The power and the correlation coefficients are near to 1.0. Aim of this study is: i) to prove with experimental data the validity of the above equation for Unicellular organisms and ii) to show that perhaps, the cells are quantum-mechanical systems. The data for body mass M (kg), density ρ (kg/m3), minimum and maximum doubling time Tdt (s) for 50 unicellular organisms are assembled from scientific sources, and the computer program `Statistics' is used for calculations. In result i) the analytical relationship from type: V×S-1 = 4.46ṡ10-11×Tdt was found, where vgr = 4.46×10-11 m/s and ii) it is shown that the products between cell mass M, cell length expressed by V/S ratio and growth rate vgr satisfied the Heisenberg uncertainty principle i.e. the inequalities V/S×M×vgr>h/2π and Tdt×M×vgr2>h/2π are valid, where h= 6.626×10-34 Jṡs is the Planck constant. This rise the question: do cells appear quantum-mechanical systems?

  18. Scaling of volume to surface ratio and doubling time in growing unicellular organisms: Do cells appear quantum-mechanical systems?

    SciTech Connect

    Atanasov, Atanas Todorov

    2014-10-06

    The scaling of physical and biological characteristics of the living organisms is a basic method for searching of new biophysical laws. In series of previous studies the author showed that in Poikilotherms, Mammals and Aves, the volume to surface ratio V×S{sup −1} (m) of organisms is proportional to their generation time T{sub gt}(s) via growth rate v (m s{sup −1}): V×S{sup −1} = v{sub gr}×T{sup r}. The power and the correlation coefficients are near to 1.0. Aim of this study is: i) to prove with experimental data the validity of the above equation for Unicellular organisms and ii) to show that perhaps, the cells are quantum-mechanical systems. The data for body mass M (kg), density ρ (kg/m{sup 3}), minimum and maximum doubling time T{sub dt} (s) for 50 unicellular organisms are assembled from scientific sources, and the computer program ‘Statistics’ is used for calculations. In result i) the analytical relationship from type: V×S{sup −1} = 4.46⋅10{sup −11}×T{sub dt} was found, where v{sub gr} = 4.46×10{sup −11} m/s and ii) it is shown that the products between cell mass M, cell length expressed by V/S ratio and growth rate v{sub gr} satisfied the Heisenberg uncertainty principle i.e. the inequalities V/S×M×v{sub gr}>h/2π and T{sub dt}×M×v{sub gr}{sup 2}>h/2π are valid, where h= 6.626×10{sup −34} J⋅s is the Planck constant. This rise the question: do cells appear quantum-mechanical systems?.

  19. Double-strand DNA break repair with replication slippage on two strands: a novel mechanism of deletion formation.

    PubMed

    MacLean, Helen E; Favaloro, Jenny M; Warne, Garry L; Zajac, Jeffrey D

    2006-05-01

    We have characterized an unusual family with two different androgen receptor (AR) gene deletions, in which we propose a novel mechanism of deletion formation has occurred. Affected individuals have the X-linked disorder androgen insensitivity syndrome, and we previously showed that different family members have deletions of different exons of the AR gene. We have now fully sequenced the deletions from affected individuals, and confirmed the presence of different deletions in different affected family members. Most affected and heterozygote individuals have a 4,430-bp deletion of exon 5 that occurred between repeated GTGGCAT motifs in introns 4 and 5. One affected hemizygous individual has a 4,033-bp deletion of exons 6 and 7 that occurred between repeated CCTC motifs in introns 5 and 7. The intron 5 breakpoint junctions of the two deletions are only 11 bp apart. Surprisingly, the maternal grandmother of the original index case was found to be mosaic for both deletional events, as well as having the normal AR gene. Karyotyping ruled out 47,XXX trisomy, indicating triple mosaicism for the two different deleted AR alleles and a normal AR allele. This triple mosaicism must have occurred early in embryonic development, as both deletions were passed on to different children. Based on these findings, we propose a novel mechanism of deletion formation. We suggest that during AR gene replication, a double strand DNA break occurred in intron 5, and that a variant of replication slippage occurred on both newly synthesized strands between the repeat motifs of microhomology, leading to the formation of the two different AR gene deletions. PMID:16619235

  20. A new quantum sealed-bid auction protocol with secret order in post-confirmation

    NASA Astrophysics Data System (ADS)

    Wang, Jing-Tao; Chen, Xiu-Bo; Xu, Gang; Meng, Xiang-Hua; Yang, Yi-Xian

    2015-10-01

    A new security protocol for quantum sealed-bid auction is proposed to resist the collusion attack from some malicious bidders. The most significant feature of this protocol is that bidders prepare their particles with secret order in post-confirmation for encoding bids. In addition, a new theorem and its proof are given based on the theory of combinatorial mathematics, which can be used as evaluation criteria for the collusion attack. It is shown that the new protocol is immune to the collusion attack and meets the demand for a secure auction. Compared with those previous protocols, the security, efficiency and availability of the proposed protocol are largely improved.

  1. Double Mantle Plume Upwelling—A Possible Formation Mechanism of Beta Plateau and Devana Chasma,Venus

    NASA Astrophysics Data System (ADS)

    Ding, N.

    2009-12-01

    Ning Ding,Zuoxun Zeng,China University of Geosciences,Wuhan,430074,China NingDing.eagle@gmail.com Introduction:Venus represents a‘one plate planet’[1],and the uplift,fractures and volcanism in Beta Regio on Venus are considered to be formed by lithosphere uplift driven by a hot plume[2]. Based on the double peaking saddle landform,we suggest the tectonic pattern of double mantle plume upwelling to interpret the formation mechanism of Beta Plateau and Devana Chasma.We take a physical modeling to validate this possibility. Model:There is no ductile shear in Venus[3],so we use quartz sands to simulate the crust of Venus.We use two wood stickes 1.5cm in diameter rising from the rubber canvas slowly and straight till about half of the model,then falling down slowly and straight.The base is a hard rubber plate,in the center of which,there are two holes 3cm in diameter,and the distance between them is 5cm.The holes are covered by rubber canvas.We use the quartz sands in colours of white, red and black with particle size of 70 mess as the model materials. Result:Fig.1:At the beginning of the wood stickes upwelling,only fine radial cracks are formed above the upwelling from central to outside.With the upwelling continue,surface energy of the fine radial cracks increase and make the cracks unstable,finally,the fine radial cracks connect each other and form a fracture zone.And then the two mantle plume downwelling,the fracture zone is developed to form a chasma at the end. Fig.2:The four profiles all form reverse faults outside and normal faults inside.But the difference is the faults in the middle of the chasma goes deeper than others.It is the pattern of Beta Plateau where the tectonic rising is cut by Devana Chasma zone in the topographic features. Fig.3:From the tow fig., we can see two points similar:a.the elevation is high and distribution area is large around the area of two upwelling and it is high around the area of chasma,but the distribution area is small

  2. Double screening

    NASA Astrophysics Data System (ADS)

    Gratia, Pierre; Hu, Wayne; Joyce, Austin; Ribeiro, Raquel H.

    2016-06-01

    Attempts to modify gravity in the infrared typically require a screening mechanism to ensure consistency with local tests of gravity. These screening mechanisms fit into three broad classes; we investigate theories which are capable of exhibiting more than one type of screening. Specifically, we focus on a simple model which exhibits both Vainshtein and kinetic screening. We point out that due to the two characteristic length scales in the problem, the type of screening that dominates depends on the mass of the sourcing object, allowing for different phenomenology at different scales. We consider embedding this double screening phenomenology in a broader cosmological scenario and show that the simplest examples that exhibit double screening are radiatively stable.

  3. The transition mechanism from a symmetric single period discharge to a period-doubling discharge in atmospheric helium dielectric-barrier discharge

    SciTech Connect

    Zhang, Dingzong; Wang, Yanhui; Wang, Dezhen

    2013-06-15

    Period-doubling and chaos phenomenon have been frequently observed in atmospheric-pressure dielectric-barrier discharges. However, how a normal single period discharge bifurcates into period-doubling state is still unclear. In this paper, by changing the driving frequency, we study numerically the transition mechanisms from a normal single period discharge to a period-doubling state using a one-dimensional self-consistent fluid model. The results show that before a discharge bifurcates into a period-doubling state, it first deviates from its normal operation and transforms into an asymmetric single period discharge mode. Then the weaker discharge in this asymmetric discharge will be enhanced gradually with increasing of the frequency until it makes the subsequent discharge weaken and results in the discharge entering a period-doubling state. In the whole transition process, the spatial distribution of the charged particle density and the electric field plays a definitive role. The conclusions are further confirmed by changing the gap width and the amplitude of the applied voltage.

  4. 31 CFR 356.33 - Does the Treasury have any discretion in the auction process?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Does the Treasury have any discretion... CIRCULAR, PUBLIC DEBT SERIES NO. 1-93) Miscellaneous Provisions § 356.33 Does the Treasury have any discretion in the auction process? (a) We have the discretion to: (1) Accept, reject, or refuse to...

  5. See Art History in a New Light: Have an Art Auction

    ERIC Educational Resources Information Center

    Benter, Doris J.

    2008-01-01

    At Portledge School in Locust Valley, New York, ninth graders in their upper school study art history for one semester. The visual arts department has created a vigorous new syllabus culminating in an hour-long mock art auction. The department selects several art movements (e.g., Post-Impressionism, Cubism, Abstract Expressionism, Social Realism,…

  6. 25 CFR 215.4 - Leases to be sold at public auction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Leases to be sold at public auction. 215.4 Section 215.4 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEAD AND ZINC MINING... provided in the regulations in this part, no lead and zinc mining lease under this part of restricted...

  7. 25 CFR 215.4 - Leases to be sold at public auction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Leases to be sold at public auction. 215.4 Section 215.4 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEAD AND ZINC MINING... provided in the regulations in this part, no lead and zinc mining lease under this part of restricted...

  8. 25 CFR 215.4 - Leases to be sold at public auction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Leases to be sold at public auction. 215.4 Section 215.4 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEAD AND ZINC MINING... provided in the regulations in this part, no lead and zinc mining lease under this part of restricted...

  9. 25 CFR 215.4 - Leases to be sold at public auction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Leases to be sold at public auction. 215.4 Section 215.4 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEAD AND ZINC MINING... provided in the regulations in this part, no lead and zinc mining lease under this part of restricted...

  10. Teaching Undergraduate Money and Banking: T-Bill Auctions and Stock Market Models

    ERIC Educational Resources Information Center

    Saros, Daniel E.

    2009-01-01

    The author offers innovative approaches to 3 topics that are typically only briefly mentioned (if at all) in money and banking courses. The first topic is a Treasury bill auction experiment in which students have an opportunity to participate directly. The results from a class of 14 money and banking students are used to explain how an instructor…

  11. 30 CFR 585.220 - What auction format may BOEM use in a lease sale?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What auction format may BOEM use in a lease sale? 585.220 Section 585.220 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Issuance of OCS Renewable Energy...

  12. 40 CFR 97.421 - Recordation of TR NOX Annual allowance allocations and auction results.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Recordation of TR NOX Annual allowance... TRADING PROGRAMS TR NOX Annual Trading Program § 97.421 Recordation of TR NOX Annual allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR NOX...

  13. 40 CFR 97.421 - Recordation of TR NOX Annual allowance allocations and auction results.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Recordation of TR NOX Annual allowance... TRADING PROGRAMS TR NOX Annual Trading Program § 97.421 Recordation of TR NOX Annual allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR NOX...

  14. 40 CFR 97.421 - Recordation of TR NOX Annual allowance allocations and auction results.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Recordation of TR NOX Annual allowance... TRADING PROGRAMS TR NOX Annual Trading Program § 97.421 Recordation of TR NOX Annual allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR NOX...

  15. 31 CFR 356.20 - How does the Treasury determine auction awards?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... yields or discount rates through successively higher yields or discount rates, up to the amount required to meet the offering amount. When necessary, we prorate bids at the highest accepted yield or... the yield or discount rate for the securities we are auctioning. (2) Accepting bids at the high...

  16. 31 CFR 356.20 - How does the Treasury determine auction awards?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... yields or discount rates through successively higher yields or discount rates, up to the amount required to meet the offering amount. When necessary, we prorate bids at the highest accepted yield or... the yield or discount rate for the securities we are auctioning. (2) Accepting bids at the high...

  17. 47 CFR 27.604 - Limitation on licenses won at auction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Limitation on licenses won at auction. 27.604 Section 27.604 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Guard Band A and B Blocks (757-758/787-788 MHz and...

  18. 49 CFR Appendix F to Part 599 - Salvage Auction Cerification Form

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Salvage Auction Cerification Form F Appendix F to Part 599 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY... CONSUMER ASSISTANCE TO RECYCLE AND SAVE ACT PROGRAM Pt. 599, App. F Appendix F to Part 599—Salvage...

  19. 49 CFR Appendix F to Part 599 - Salvage Auction Certification Form

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Salvage Auction Certification Form F Appendix F to Part 599 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY... CONSUMER ASSISTANCE TO RECYCLE AND SAVE ACT PROGRAM Pt. 599, App. F Appendix F to Part 599—Salvage...

  20. 49 CFR Appendix F to Part 599 - Salvage Auction Certification Form

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 7 2011-10-01 2011-10-01 false Salvage Auction Certification Form F Appendix F to Part 599 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY... CONSUMER ASSISTANCE TO RECYCLE AND SAVE ACT PROGRAM Pt. 599, App. F Appendix F to Part 599—Salvage...

  1. 31 CFR 356.11 - How are bids submitted in an auction?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Direct, you may submit bids by using one of our approved methods, e.g., computer, automated telephone... telephone call to designated Treasury employees if you submit them prior to the relevant bidding deadline... was mailed prior to the auction date. (3) If you are submitting a bid by computer or...

  2. 31 CFR 356.11 - How are bids submitted in an auction?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Direct, you may submit bids by using one of our approved methods, e.g., computer, automated telephone... telephone call to designated Treasury employees if you submit them prior to the relevant bidding deadline... was mailed prior to the auction date. (3) If you are submitting a bid by computer or...

  3. 31 CFR 356.11 - How are bids submitted in an auction?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Direct, you may submit bids by using one of our approved methods, e.g., computer, automated telephone... telephone call to designated Treasury employees if you submit them prior to the relevant bidding deadline... it was mailed prior to the auction date. (3) If you are submitting a bid by computer or...

  4. 9 CFR 2.76 - Records: Operators of auction sales and brokers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... breed or type of animal; (ii) The sex of the animal; and (iii) The date of birth or approximate age; and... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Records: Operators of auction sales and brokers. 2.76 Section 2.76 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION...

  5. 9 CFR 2.76 - Records: Operators of auction sales and brokers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... breed or type of animal; (ii) The sex of the animal; and (iii) The date of birth or approximate age; and... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Records: Operators of auction sales and brokers. 2.76 Section 2.76 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION...

  6. 9 CFR 2.76 - Records: Operators of auction sales and brokers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... breed or type of animal; (ii) The sex of the animal; and (iii) The date of birth or approximate age; and... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Records: Operators of auction sales and brokers. 2.76 Section 2.76 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION...

  7. 9 CFR 2.76 - Records: Operators of auction sales and brokers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... breed or type of animal; (ii) The sex of the animal; and (iii) The date of birth or approximate age; and... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Records: Operators of auction sales and brokers. 2.76 Section 2.76 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION...

  8. 9 CFR 2.76 - Records: Operators of auction sales and brokers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... breed or type of animal; (ii) The sex of the animal; and (iii) The date of birth or approximate age; and... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Records: Operators of auction sales and brokers. 2.76 Section 2.76 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION...

  9. 77 FR 9655 - Mobility Fund Phase I Auction Updated List of Potentially Eligible Census Blocks

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ..., 77 FR 7152, February 10, 2012, comments are due on or before February 24, 2012. Reply comments are... Public Notice, 77 FR 7152, February 10, 2012, all filings in response to the notice must refer to AU... program requirements in the Auction 901 (Mobility Fund Phase I) Comment Public Notice, 77 FR...

  10. Revisiting "The Loophole of the Improved Secure Quantum Sealed-Bid Auction with Post-Confirmation and Solution"

    NASA Astrophysics Data System (ADS)

    Wang, Qing-Le; Zhang, Wei-Wei; Su, Qi

    2014-09-01

    Recently, Luo et al. make a detailed analysis on the security of quantum sealed-bid auction with post-confirmation protocol (Quantum Information Processing, Volume 11, Issue 6, pp 1359-1369, 2012) and present the corresponding improved strategy for its loophole. Unfortunately, we find their improved version is still not as secure as expected, since it is vulnerable to malicious bidders in collusion with the auctioneer. And there is an unreasonable suspicion in the honesty of the auctioneer for special situation. Then we propose an improved strategy, which can perfectly defeat kinds of attacks.

  11. A Double-Hotdog with a New Trick: Structure and Mechanism of the trans-Acyltransferase Polyketide Synthase Enoyl-isomerase

    PubMed Central

    2015-01-01

    Many polyketide natural products exhibit invaluable medicinal properties, yet much remains to be understood regarding the machinery responsible for their biosynthesis. The recently discovered trans-acyltransferase polyketide synthases employ processing enzymes that catalyze modifications unique from those of the classical cis-acyltransferase polyketide synthases. The enoyl-isomerase domains of these megasynthases shift double bonds and are well-represented by an enzyme that helps forge the triene system within the antibiotic produced by the prototypical bacillaene synthase. This first crystal structure of an enoyl-isomerase, at 1.73 Å resolution, not only revealed relationships between this class of enzymes and dehydratases but also guided an investigation into the mechanism of double bond migration. The catalytic histidine, positioned differently from that of dehydratases, was demonstrated to independently shuttle a proton between the γ- and α-positions of the intermediate. This unprecedented mechanism highlights the catalytic diversity of divergent enzymes within trans-acyltransferase polyketide synthases. PMID:25089587

  12. The influence of an online auction's product price and e-retailer reputation on consumers' perception, attitude, and behavioral intention.

    PubMed

    Wu, Wann-Yih; Huang, Po-Ching; Fu, Chen-Su

    2011-06-01

    Online auctions combine the conventional auction model with information technology. However, information asymmetry within such auctions causes risks and uncertainties that influence consumer purchase intentions. In this study, a 2 (product price: high vs. low) × 2 (e-retailer reputation: high vs. low) experimental design was used to understand whether the product price and e-retailer reputation will influence consumers' perceived risk, attitude toward the website and purchase intention. The results of this study indicate that perceived risk negatively influences consumer attitude toward the website and online purchase intention, while consumer attitude toward the website positively influences purchase intention. Moreover, involvement moderates the influence of product price and e-retailer reputation only on social risk but does not have a significant effect on consumer attitude toward the website. This study contributes to a more comprehensive understanding of online auction users' behavior. Finally, the managerial implications, limitations and future research directions are also provided. PMID:21332721

  13. 78 FR 72081 - Closed Auction of AM Broadcast Construction Permits Scheduled for May 6, 2014; Comment Sought on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS... Competitive Bidding Procedures for Auction 84 AGENCY: Federal Communications Commission. ACTION: Notice... the instructions for submitting comments. Federal Communications Commission's Web site:...

  14. Effect of single and double austenitization treatments on the microstructure and mechanical properties of 16Cr-2Ni steel

    SciTech Connect

    Balan, K.P.; Venugopal Reddy, A.; Sarma, D.S.

    1999-06-01

    Double austenitization (DA) treatment is found to yield the best combination of strength and toughness in both low-temperature as well as high-temperature tempered conditions as compared to single austenitization (SA) treatments. Obtaining the advantages of double austenitization (DA) to permit dissolution of alloy carbides without significant grain coarsening was attempted in AISI 431 type martensitic stainless steel. Structure-property correlation after low-temperature tempering (200 C) as well as high-temperature double tempering (650 + 600 C) was carried out for three austenitization treatments through SA at 1000 C, SA at 1070 C, and DA at 1070 + 1000 C. While the increase in strength after DA treatment and low-temperature tempering at 200 C is due to the increased amount of carbon in solution as a result of dissolution of alloy carbides during first austenitization, the increased toughness is attributable to the increased quantity of retained austenite. After double tempering (650 + 600 C), strength and toughness are mainly found to depend on the precipitation and distribution of carbides in the microstructure and the grain size effect.

  15. A Supplier Bidding Strategy Through Q-Learning Algorithm in Electricity Auction Markets

    NASA Astrophysics Data System (ADS)

    Xiong, Gaofeng; Hashiyama, Tomonori; Okuma, Shigeru

    One of the most important issues for power suppliers in the deregulated electric industry is how to bid into the electricity auction market to satisfy their profit-maximizing goals. Based on the Q-Learning algorithm, this paper presents a novel supplier bidding strategy to maximize supplier’s profit in the long run. In this approach, the supplier bidding strategy is viewed as a kind of stochastic optimal control problem and each supplier can learn from experience. A competitive day-ahead electricity auction market with hourly bids is assumed here, where no supplier possesses the market power. The dynamics and the incomplete information of the market are considered. The impacts of suppliers’ strategic bidding on the market price are analyzed under uniform pricing rule and discriminatory pricing rule. Agent-based simulations are presented. The simulation results show the feasibility of the proposed bidding strategy.

  16. A Q-Learning-Based Supplier Bidding Strategy in Electricity Auction Market

    NASA Astrophysics Data System (ADS)

    Xiong, Gaofeng; Hashiyama, Tomonori; Okuma, Shigeru

    One of the most important issues for power suppliers in the deregulated electric industry is how to bid into the electricity auction market to satisfy their profit-maximizing goals. Based on the Q-Learning algorithm, this paper presents a novel supplier bidding strategy to maximize supplier’s profit in the long run. In this approach, the supplier bidding strategy is viewed as one kind of stochastic optimal control problem and each supplier can learn from experience. A competitive day-ahead electricity auction market with hourly bids is assumed here, where no supplier possesses the market power and all suppliers winning the market are paid based on their own bid prices. The dynamics and the incomplete information of the market are considered. The impact of suppliers’ strategic bidding on the market price is analyzed. Agent-based simulations are presented. The simulation results show the feasibility of the proposed bidding strategy.

  17. Equilibrium Strategy and Population-Size Effects in Lowest Unique Bid Auctions

    NASA Astrophysics Data System (ADS)

    Pigolotti, Simone; Bernhardsson, Sebastian; Juul, Jeppe; Galster, Gorm; Vivo, Pierpaolo

    2012-02-01

    In lowest unique bid auctions, N players bid for an item. The winner is whoever places the lowest bid, provided that it is also unique. We use a grand canonical approach to derive an analytical expression for the equilibrium distribution of strategies. We then study the properties of the solution as a function of the mean number of players, and compare them with a large data set of internet auctions. The theory agrees with the data with striking accuracy for small population-size N, while for larger N a qualitatively different distribution is observed. We interpret this result as the emergence of two different regimes, one in which adaptation is feasible and one in which it is not. Our results question the actual possibility of a large population to adapt and find the optimal strategy when participating in a collective game.

  18. Collective induction without cooperation? Learning and knowledge transfer in cooperative groups and competitive auctions.

    PubMed

    Maciejovsky, Boris; Budescu, David V

    2007-05-01

    There is strong evidence that groups perform better than individuals do on intellective tasks with demonstrably correct solutions. Typically, these studies assume that group members share common goals. The authors extend this line of research by replacing standard face-to-face group interactions with competitive auctions, allowing for conflicting individual incentives. In a series of studies involving the well-known Wason selection task, they demonstrate that competitive auctions induce learning effects equally impressive as those of standard group interactions, and they uncover specific and general knowledge transfers from these institutions to new reasoning problems. The authors identify payoff feedback and information pooling as the driving factors underlying these findings, and they explain these factors within the theoretical framework of collective induction. PMID:17484609

  19. Biased Random-Key Genetic Algorithms for the Winner Determination Problem in Combinatorial Auctions.

    PubMed

    de Andrade, Carlos Eduardo; Toso, Rodrigo Franco; Resende, Mauricio G C; Miyazawa, Flávio Keidi

    2015-01-01

    In this paper we address the problem of picking a subset of bids in a general combinatorial auction so as to maximize the overall profit using the first-price model. This winner determination problem assumes that a single bidding round is held to determine both the winners and prices to be paid. We introduce six variants of biased random-key genetic algorithms for this problem. Three of them use a novel initialization technique that makes use of solutions of intermediate linear programming relaxations of an exact mixed integer linear programming model as initial chromosomes of the population. An experimental evaluation compares the effectiveness of the proposed algorithms with the standard mixed linear integer programming formulation, a specialized exact algorithm, and the best-performing heuristics proposed for this problem. The proposed algorithms are competitive and offer strong results, mainly for large-scale auctions. PMID:25299242

  20. 31 CFR 356.11 - How are bids submitted in an auction?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false How are bids submitted in an auction? 356.11 Section 356.11 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT SALE AND ISSUE OF MARKETABLE BOOK-ENTRY TREASURY BILLS, NOTES, AND BONDS...

  1. Improving the secrecy rate by turning foes to allies: An auction scheme

    NASA Astrophysics Data System (ADS)

    Ma, Ya-Yan; Wang, Bao-Yun

    2015-09-01

    Security against eavesdroppers is a critical issue in cognitive radio networks (CRNs). In this paper, a scenario consisting of one primary pair and multiple secondary pairs is considered. The secondary transmitters (STs) work in half-duplex mode and they are potential eavesdroppers on the primary transmission unless they are allowed to simultaneously transmit with the primary transmitter (PT). A modified second-price sealed-bid auction scheme is employed to model the interaction between the PT and STs. With the proposed auction scheme, the hostile relationship between the PT and STs is transformed into a cooperative relationship. An iterative algorithm based on the max-min criteria is proposed to find the optimal bidding power of the STs for an access chance in the presence of multiple eavesdroppers. Numerical results show that the proposed auction scheme not only improves the PT’s security but also increases the access opportunities of the STs. Project supported by the National Natural Science Foundation of China (Grant Nos. 61271232 and 61372126) and the University Postgraduate Research and Innovation Project in Jiangsu Province, China (Grant No. CXZZ12-0472).

  2. Bulk-wave and guided-wave photoacoustic evaluation of the mechanical properties of aluminum/silicon nitride double-layer thin films.

    PubMed

    Zhang, Feifei; Krishnaswamy, Sridhar; Lilley, Carmen M

    2006-12-01

    The development of devices made of micro- and nano-structured thin film materials has resulted in the need for advanced measurement techniques to characterize their mechanical properties. Photoacoustic techniques, which use pulsed laser irradiation to nondestructively induce very high frequency ultrasound in a test object via rapid thermal expansion, are suitable for nondestructive and non-contact evaluation of thin films. In this paper, we compare two photoacoustic techniques to characterize the mechanical parameters of edge-supported aluminum and silicon nitride double-layer thin films. The elastic properties and residual stresses in such films affect their mechanical performance. In a first set of experiments, a femtosecond transient pump-probe technique is used to investigate the Young's moduli of the aluminum and silicon nitride layers by launching ultra-high frequency bulk acoustic waves in the films. The measured transient signals are compared with simulated transient thermoelastic signals in multi-layer structures, and the elastic moduli are determined. Independent pump-probe tests on silicon substrate-supported region and unsupported region are in good agreement. In a second set of experiments, dispersion curves of the A(0) mode of the Lamb waves that propagate along the unsupported films are measured using a broadband photoacoustic guided-wave method. The residual stresses and flexural rigidities for the same set of double-layer membranes are determined from these dispersion curves. Comparisons of the results obtained by the two photoacoustic techniques are made and discussed. PMID:16899268

  3. Mode-Specific Tunneling Splittings for a Sequential Double-Hydrogen Transfer Case: An Accurate Quantum Mechanical Scheme.

    PubMed

    Ren, Yinghui; Bian, Wensheng

    2015-05-21

    We present the first accurate quantum dynamics calculations of mode-specific tunneling splittings in a sequential double-hydrogen transfer process. This is achieved in the vinylidene-acetylene system, the simplest molecular system of this kind, and by large-scale parallel computations with an efficient theoretical scheme developed by us. In our scheme, basis functions are customized for the hydrogen transfer process; a 4-dimensional basis contraction strategy is combined with the preconditioned inexact spectral transform method; efficient parallel implementation is achieved. Mode-specific permutation tunneling splittings of vinylidene states are reported and tremendous mode-specific promotion effects are revealed; in particular, the CH2 rock mode enhances the ground-state splitting by a factor of 10(3). We find that the ground-state vinylidene has a reversible-isomerization time of 622 ps, much longer than all previous estimates. Our calculations also shed light on the importance of the deep intermediate well and vibrational excitation in the double-hydrogen transfer processes. PMID:26263255

  4. Double Your Pleasure, Double Your Funds.

    ERIC Educational Resources Information Center

    McCall, Miles; Sitton, Bob

    1999-01-01

    Discusses a variety of fun activities that college and universities can develop as alumni fund-raising events: a golf tournament; scholarship auctions (silent, on-the-spot, live televised, and live); charitable raffles; duck dashes; themed banquets; and a tuition raffle. (MSE)

  5. Modeling effects of gas bubbles on the mechanical behaviors of Ag/Bi-2212 round wires using a double cantilever beam bridge model

    NASA Astrophysics Data System (ADS)

    Lu, Yurong; Wang, Zhongtong; Yong, Huadong; Zhou, Youhe

    2016-07-01

    Due to the larger current-carrying property, Bi2Sr2CaCu2Ox (Bi2212) superconductors have a great potential application in high field magnet. Bi2212 superconducting material can be fabricated as an isotropic round wire. However, there is 30% void space in the wire, such as gas bubbles. The void space has a larger influence on the property of the wire. In this paper, we will study the effect of gas bubble on the fracture behavior. Based on the double cantilever beam model and critical state theory, the mechanical behavior of Bi2212 wire is studied for decreasing field. Two different damage mechanisms are discussed using the strain energy release rate and strain of bridge. The results show that the large gas bubble can increase the strain of bridge. The central filaments with gas bubble are easier to be damaged than the edge filaments with gas bubble.

  6. The mechanical properties and cytotoxicity of cell-laden double-network hydrogels based on photocrosslinkable gelatin and gellan gum biomacromolecules.

    PubMed

    Shin, Hyeongho; Olsen, Bradley D; Khademhosseini, Ali

    2012-04-01

    A major goal in the application of hydrogels for tissue engineering scaffolds, especially for load-bearing tissues such as cartilage, is to develop hydrogels with high mechanical strength. In this study, a double-network (DN) strategy was used to engineer strong hydrogels that can encapsulate cells. We improved upon previously studied double-network (DN) hydrogels by using a processing condition compatible with cell survival. The DN hydrogels were created by a two-step photocrosslinking using gellan gum methacrylate (GGMA) for the rigid and brittle first network, and gelatin methacrylamide (GelMA) for the soft and ductile second network. We controlled the degree of methacrylation of each polymer so that they obtain relevant mechanical properties as each network. The DN was formed by photocrosslinking the GGMA, diffusing GelMA into the first network, and photocrosslinking the GelMA to form the second network. The formation of the DN was examined by diffusion tests of the large GelMA molecules into the GGMA network, the resulting enhancement in the mechanical properties, and the difference in mechanical properties between GGMA/GelMA single networks (SN) and DNs. The resulting DN hydrogels exhibited the compressive failure stress of up to 6.9 MPa, which approaches the strength of cartilage. It was found that there is an optimal range of the crosslink density of the second network for high strength of DN hydrogels. DN hydrogels with a higher mass ratio of GelMA to GGMA exhibited higher strength, which shows promise in developing even stronger DN hydrogels in the future. Three dimensional (3D) encapsulation of NIH-3T3 fibroblasts and the following viability test showed the cell-compatibility of the DN formation process. Given the high strength and the ability to encapsulate cells, the DN hydrogels made from photocrosslinkable macromolecules could be useful for the regeneration of load-bearing tissues. PMID:22265786

  7. The mechanical properties and cytotoxicity of cell-laden double-network hydrogels based on photocrosslinkable gelatin and gellan gum biomacromolecules

    PubMed Central

    Shin, Hyeongho; Olsen, Bradley D.; Khademhosseini, Ali

    2012-01-01

    A major goal in the application of hydrogels for tissue engineering scaffolds, especially for load-bearing tissues such as cartilage, is to develop hydrogels with high mechanical strength. In this study, a double-network (DN) strategy was used to engineer strong hydrogels that can encapsulate cells. We improved upon previously studied double-network (DN) hydrogels by using a processing condition compatible with cell survival. The DN hydrogels were created by a two-step photocrosslinking using gellan gum methacrylate (GGMA) for the rigid and brittle first network, and gelatin methacrylamide (GelMA) for the soft and ductile second network. We controlled the degree of methacrylation of each polymer so that they obtain relevant mechanical properties as each network. The DN was formed by photocrosslinking the GGMA, diffusing GelMA into the first network, and photocrosslinking the GelMA to form the second network. The formation of the DN was examined by diffusion tests of the large GelMA molecules into the GGMA network, the resulting enhancement in the mechanical properties, and the difference in mechanical properties between GGMA/GelMA single networks (SN) and DNs. The resulting DN hydrogels exhibited the compressive failure stress of up to 6.9 MPa, which approaches the strength of cartilage. It was found that there is an optimal range of the crosslink density of the second network for high strength of DN hydrogels. DN hydrogels with a higher mass ratio of GelMA to GGMA exhibited higher strength, which shows promise in developing even stronger DN hydrogels in the future. Three dimensional (3D) encapsulation of NIH-3T3 fibroblasts and the following viability test showed the cell-compatibility of the DN formation process. Given the high strength and the ability to encapsulate cells, the DN hydrogels made from photocrosslinkable macromolecules could be useful for the regeneration of load-bearing tissues. PMID:22265786

  8. A Study on the Propulsive Mechanism of a Double Jointed Fish Robot Utilizing Self-Excitation Control

    NASA Astrophysics Data System (ADS)

    Nakashima, Motomu; Ohgishi, Norifumi; Ono, Kyosuke

    This paper describes a numerical and experimental study of a double jointed fish robot utilizing self-excitation control. The fish robot is composed of a streamlined body and a rectangular caudal fin. The body length is 280mm and it has a DC motor to actuate its first joint and a potentiometer to detect the angle of its second joint. The signal from the potentiometer is fed back into the DC motor, so that the system can be self-excited. In order to obtain a stable oscillation and a resultant stable propulsion, a torque limiter circuit is employed. From the experiment, it has been found that the robot can stably propel using this control and the maximum propulsive speed is 0.42m/s.

  9. 78 FR 45524 - Auction of H Block Licenses in the 1915-1920 MHz and 1995-2000 MHz Bands; Comment Sought on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    .... SUMMARY: This document announces the intention to hold an auction of H Block licenses in the 1915-1920 and...) announces its intention to hold an auction of licenses in the 1915-1920 MHz (Lower H Block) and 1995-2000... with the bidders' need to study round results and adjust their bidding strategies. Under this...

  10. 75 FR 32773 - Auction of 218-219 MHz Service and Phase II 220 MHz Service Licenses Scheduled for December 7...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... certain portions of the electromagnetic spectrum or provide service to certain areas in their geographic..., Auctions and Spectrum Access Division: For auction legal questions: Sayuri Rajapakse at (202) 418-0660; for... 89 will include a total of 1,868 licenses. These include licenses for spectrum not previously...

  11. The impact of product information and trials on demand for smokeless tobacco and cigarettes: Evidence from experimental auctions

    PubMed Central

    Rousu, Matthew C.; O'Connor, Richard; Thrasher, James F; June, Kristie; Bansal-Travers, Maansi; Pitcavage, James

    2014-01-01

    Introduction Epidemiological and toxicological evidence suggests lower risk of smokeless tobacco (ST) products compared to cigarettes. Less is known, however, about consumer perceptions and use of novel forms of ST, including snus and dissolvable tobacco. Methods In this study, we conducted in-person experimental auctions in Buffalo, NY, Columbia, SC, and Selinsgrove, PA with 571 smokers to test the impact of information and product trials on smokers’ preferences. Auctions were conducted between November 2010-November 2011. Results We found no evidence of an impact of product trials on demand in our auctions. Anti-ST information increased demand for cigarettes when presented alone, but when presented with Pro-ST information it decreased demand for cigarettes. It did not decrease demand for ST products. Anti-smoking information increased demand for ST products, but did not affect cigarette demand. Conclusions These findings suggest that credible and effective communications about tobacco harm reduction should reinforce the negative effects of smoking. PMID:24321456

  12. Central mechanisms of controlled-release metoprolol in migraine: a double-blind, placebo-controlled study.

    PubMed

    Siniatchkin, M; Andrasik, F; Kropp, P; Niederberger, U; Strenge, H; Averkina, N; Lindner, V; Stephani, U; Gerber, W-D

    2007-09-01

    beta-Blockers are widely used in the prophylaxis of migraine and have been described as very effective drugs in many studies. Some investigators have demonstrated that the clinical improvement of migraine corresponds to the normalization of the contingent negative variation (CNV), a slow cortical potential measuring cortical information processing. However, most of these studies have contained a variety of methodological pitfalls, which we attempted to address in the current study. Twenty patients suffering from migraine without aura were randomly divided into two groups. The groups were treated either with controlled-release metoprolol or placebo for 3 months, using a double-blind design. Twice before and once after each month of the treatment the CNV was recorded. After 3 months, a significant reduction of migraine frequency, duration and intensity was demonstrated for the metoprolol compared with the placebo group. The CNV was characterized by a marked reduction of the amplitude of the total CNV and postimperative negative variation and normalization of the eartly CNV habituation following treatment. Therefore, metoprolol may exert its prophylactic effect in migraine through the influence on cortical information processing and excitability represented by the CNV. PMID:17680819

  13. Underlying mechanisms for normal heat transport in one-dimensional anharmonic oscillator systems with a double-well interparticle interaction

    NASA Astrophysics Data System (ADS)

    Xiong, Daxing

    2016-04-01

    Previous studies have suggested a crossover from superdiffusive to normal heat transport in one-dimensional (1D) anharmonic oscillator systems with a double-well type interatomic interaction like V(ξ )=-{ξ2}/2+{ξ4}/4 , when the system temperature is varied. In order to better understand this unusual manner of thermal transport, here we perform a direct dynamics simulation to examine how the spreading processes of the three physical quantities, i.e. the heat, the total energy and the momentum, would depend on temperature. We find three main points that are worth noting. (i) The crossover from superdiffusive to normal heat transport is well verified from a new perspective of heat spread. (ii) The spreading of the total energy is found to be very distinct from heat diffusion, especially under some temperature regimes, energy is strongly localized, while heat can be superdiffusive. So one should take care to derive a general connection between the heat conduction and energy diffusion. (iii) In a narrow range of temperatures, the spreading of momentum implies clear unusual non-ballistic behaviors; however, such unusual transport of momentum cannot be directly related to the normal transport of heat. An analysis of phonon spectra suggests that one should also take the effects of phonon softening into account. All of these results may provide insights into establishing the connection between the macroscopic heat transport and the underlying dynamics in 1D systems.

  14. Exchange mechanism of half-metallic ferromagnetism of TiO 2 doped with double impurities: A first-principles ASW study

    NASA Astrophysics Data System (ADS)

    Fakhim Lamrani, A.; Belaiche, M.; Benyoussef, A.; El Kenz, A.; Saidi, E. H.

    2010-02-01

    The electronic structure and ferromagnetic properties of rutile TiO 2 doped with double-impurities Ti 1-2xCr xMn xO 2 has been investigated using first-principles calculations within the density-functional theory (DFT) and the local density approximation (LDA), functional for treating the effects of exchange and correlation. They were performed using the scalar-relativistic implementation of the augmented spherical wave (ASW). The advantages of doping TiO 2 with double impurities instead of single impurities are the increase of the total moment of the system and the exhibition of the half-metallic ferromagnetic nature in Cr- and Mn-doped TiO 2 rutile. These behaviors are due to the hybridization of Cr 3d states and nearest-neighboring O 2p states. The spin-spin interaction between magnetic impurities examined by the total energy between parallel and antiparallel aligned states indicated that the Cr and Mn impurities are energetically favorable to be parallel coupled, which mean that the ferromagnetic state is more stable than the ferrimagnetic one. We proposed a bond magnetic polarons (BMP) model, based on localized carriers, to explain the mechanism of ferromagnetism in these systems.

  15. Direct electron-impact mechanism of excitation of mercury monobromide in a double-pulse dielectric-barrier-discharge HgBr lamp

    NASA Astrophysics Data System (ADS)

    Datsyuk, V. V.; Izmailov, I. A.; Naumov, V. V.; Kochelap, V. A.

    2016-08-01

    In a nonequlibrium plasma of a gas-discharge HgBr lamp, the terminal electronic state of the HgBr(B–X) radiative transition with a peak wavelength of 502 nm remains populated for a relatively long time and is repeatedly excited to the B state in collisions with plasma electrons. This transfer of the HgBr molecules from the ground state X to the excited state B is the main mechanism of formation of the light-emitting molecules especially when the lamp is excited by double current pulses. According to our simulations, due to the electron-induced transitions between HgBr(X) and HgBr(B), the output characteristics of the DBD lamp operating in a double-pulse regime are better than those of the lamp operating in a single-pulse regime. In the considered case, the peak power is calculated to increase by a factor of about 2 and the lamp efficiency increases by about 50%.

  16. Double-Strand Break Repair by Interchromosomal Recombination: An In Vivo Repair Mechanism Utilized by Multiple Somatic Tissues in Mammals

    PubMed Central

    White, Ryan R.; Sung, Patricia; Vestal, C. Greer; Benedetto, Gregory; Cornelio, Noelle; Richardson, Christine

    2013-01-01

    Homologous recombination (HR) is essential for accurate genome duplication and maintenance of genome stability. In eukaryotes, chromosomal double strand breaks (DSBs) are central to HR during specialized developmental programs of meiosis and antigen receptor gene rearrangements, and form at unusual DNA structures and stalled replication forks. DSBs also result from exposure to ionizing radiation, reactive oxygen species, some anti-cancer agents, or inhibitors of topoisomerase II. Literature predicts that repair of such breaks normally will occur by non-homologous end-joining (in G1), intrachromosomal HR (all phases), or sister chromatid HR (in S/G2). However, no in vivo model is in place to directly determine the potential for DSB repair in somatic cells of mammals to occur by HR between repeated sequences on heterologs (i.e., interchromosomal HR). To test this, we developed a mouse model with three transgenes—two nonfunctional green fluorescent protein (GFP) transgenes each containing a recognition site for the I-SceI endonuclease, and a tetracycline-inducible I-SceI endonuclease transgene. If interchromosomal HR can be utilized for DSB repair in somatic cells, then I-SceI expression and induction of DSBs within the GFP reporters may result in a functional GFP+ gene. Strikingly, GFP+ recombinant cells were observed in multiple organs with highest numbers in thymus, kidney, and lung. Additionally, bone marrow cultures demonstrated interchromosomal HR within multiple hematopoietic subpopulations including multi-lineage colony forming unit–granulocyte-erythrocyte-monocyte-megakaryocte (CFU-GEMM) colonies. This is a direct demonstration that somatic cells in vivo search genome-wide for homologous sequences suitable for DSB repair, and this type of repair can occur within early developmental populations capable of multi-lineage differentiation. PMID:24349572

  17. A Winner Determination Algorithm for Combinatorial Auctions Based on Hybrid Artificial Fish Swarm Algorithm

    NASA Astrophysics Data System (ADS)

    Zheng, Genrang; Lin, ZhengChun

    The problem of winner determination in combinatorial auctions is a hotspot electronic business, and a NP hard problem. A Hybrid Artificial Fish Swarm Algorithm(HAFSA), which is combined with First Suite Heuristic Algorithm (FSHA) and Artificial Fish Swarm Algorithm (AFSA), is proposed to solve the problem after probing it base on the theories of AFSA. Experiment results show that the HAFSA is a rapidly and efficient algorithm for The problem of winner determining. Compared with Ant colony Optimization Algorithm, it has a good performance with broad and prosperous application.

  18. A Robust Open Ascending-price Multi-unit Auction Protocol against False-name Bids

    NASA Astrophysics Data System (ADS)

    Iwasaki, Atsushi; Yokoo, Makoto; Terada, Kenji

    This paper develops a new ascending-price multi-unit auction protocol that has following characteristics: (i) it has an open format, (ii) sincere bidding is an equilibrium strategy even if the marginal utilities of each agent can increase and agents can submit false-name bids. False-name bids are bids submitted under fictitious names such as multiple e-mail addresses, which can be done easily in the Internet. This is the first protocol that has these two characteristics. We show that our new protocol outperforms an existing protocol, which satisfies (ii), with respect to the social surplus and the seller's revenue.

  19. Analysis of interface formation mechanism in GaN double-polarity selective-area growth by metalorganic vapor phase epitaxy

    NASA Astrophysics Data System (ADS)

    Kuze, Kenta; Osumi, Noriyuki; Fujita, Yohei; Inoue, Yoku; Nakano, Takayuki

    2016-05-01

    The fabrication of quasi-phase-matching (QPM) crystals by selective-area growth on the two asymmetrically polar surfaces of GaN is examined. We attempted the fabrication of GaN-QPM crystals by one-time growth using a carbon mask. For GaN double-polarity selective-area growth (DP-SAG), we investigated the effect of varied nitriding times of the Al2O3 templates patterned with the carbon mask. We optimized the nitriding conditions for the DP-SAG process, and evaluated the substrate fabricated by the optimized DP-SAG process. In addition, we examined the interface formation mechanism of DP-GaN fabricated by GaN DP-SAG process. We determined that it is possible to fabricate DP-GaN with a sharp interface by optimizing the growth conditions.

  20. Chemisorption Mechanism of DNA on Mg/Fe Layered Double Hydroxide Nanoparticles: Insights into Engineering Effective SiRNA Delivery Systems.

    PubMed

    Lu, Mingsheng; Shan, Zhi; Andrea, Kori; MacDonald, Bruce; Beale, Stefanie; Curry, Dennis E; Wang, Li; Wang, Shujun; Oakes, Ken D; Bennett, Craig; Wu, Wenhui; Zhang, Xu

    2016-03-22

    Layered double hydroxide nanoparticles (LDH NPs) have attracted interest as an effective gene delivery vehicle in biomedicine. Recent advances in clinic trials have demonstrated the efficacy of Mg/Fe LDHs for hyperphosphatemia treatment, but their feasibility for gene delivery has not been systematically evaluated. As a starting point, we aimed to study the interaction between oligo-DNA and Mg/Fe LDH NPs. Our investigation revealed the chemisorption mechanism of DNA on Mg/Fe LDH surfaces, wherein the phosphate backbone of the DNA polymer coordinates with the metal cations of the LDH lattice via the ligand-exchange process. This mechanistic insight may facilitate future gene delivery applications using Mg/Fe LDH NPs. PMID:26919981

  1. Mechanism of Action of Sulforaphane as a Superoxide Radical Anion and Hydrogen Peroxide Scavenger by Double Hydrogen Transfer: A Model for Iron Superoxide Dismutase.

    PubMed

    Prasad, Ajit Kumar; Mishra, P C

    2015-06-25

    The mechanism of action of sulforaphane as a scavenger of superoxide radical anion (O2(•-)) and hydrogen peroxide (H2O2) was investigated using density functional theory (DFT) in both gas phase and aqueous media. Iron superoxide dismutase (Fe-SOD) involved in scavenging superoxide radical anion from biological media was modeled by a complex consisting of the ferric ion (Fe(3+)) attached to three histidine rings. Reactions related to scavenging of superoxide radical anion by sulforaphane were studied using DFT in the presence and absence of Fe-SOD represented by this model in both gas phase and aqueous media. The scavenging action of sulforaphane toward both superoxide radical anion and hydrogen peroxide was found to involve the unusual mechanism of double hydrogen transfer. It was found that sulforaphane alone, without Fe-SOD, cannot scavenge superoxide radical anion in gas phase or aqueous media efficiently as the corresponding reaction barriers are very high. However, in the presence of Fe-SOD represented by the above-mentioned model, the scavenging reactions become barrierless, and so sulforaphane scavenges superoxide radical anion by converting it to hydrogen peroxide efficiently. Further, sulforaphane was found to scavenge hydrogen peroxide also very efficiently by converting it into water. Thus, the mechanism of action of sulforaphane as an excellent antioxidant has been unravelled. PMID:26020652

  2. Theoretical study of the aluminum distribution effects on the double proton transfer mechanisms upon adsorption of 4,4'-bipyridine on H-ZSM-5.

    PubMed

    Akacem, Yamina; Castellà-Ventura, Martine; Kassab, Emile

    2012-02-01

    The aluminum distribution effects on the adsorption of 4,4'-bipyridine (44BPY) in the straight channel of H-ZSM-5 simulated by two ten-membered ring clusters (2-10T) have been investigated by DFT methods. The energetic and structural properties of the complexes formed upon interaction of 44BPY with the zeolite Brønsted acid sites for six different aluminum distributions were determined by B3LYP/6-31+G* calculations. Dispersion energies were estimated by performing single point calculations at the MP2 and M06-2X levels. Interaction energies were corrected for basis set superposition error (BSSE). The minimum energy pathways of the double proton transfer from H-ZSM-5 to 44BPY were characterized. Two mechanisms are proposed: a concerted mechanism in which both protons are simultaneously transferred giving the bidentate ion pair complex (44BPYH₂²⁺/2-10T²⁻) and a consecutive mechanism in which one proton is transferred directly leading to the monodentate ion pair complex (44BPYH⁺/2-10T⁻), whereas the second proton can be transferred according to Al distribution. The formation of monodentate or bidentate complexes strongly depends on the Al distribution. PMID:22220497

  3. New mechanism of γ-H2AX generation: Surfactant-induced actin disruption causes deoxyribonuclease I translocation to the nucleus and forms DNA double-strand breaks.

    PubMed

    Zhao, Xiaoxu; Yang, Gang; Toyooka, Tatsushi; Ibuki, Yuko

    2015-12-01

    We previously showed that nonionic surfactants, nonylphenol polyethoxylates (NPEOs), induced phosphorylation of histone H2AX, forming γ-H2AX. In this study, we analyzed the mechanism of γ-H2AX generation by an NPEO with 15 ethylene oxide units (NPEO(15)). In MCF-7 breast carcinoma cells, NPEO(15) treatment induced γ-H2AX in a dose-dependent manner. EDTA and ZnCl2, two inhibitors of deoxyribonuclease I (DNase I), inhibited both the γ-H2AX and DNA double-strand breaks induced by NPEO(15). NPEO(15) disrupted filamentous actin and released free DNase I as detected by cell fractionation analysis. Based on immunofluorescence staining of DNase I and monitoring DNase I-GFP localization, DNase I was translocated from the cytosol to the nucleus of cells after treatment with NPEO(15). This translocation did not occur with the common DNA damage inducers ultraviolet B irradiation and hydrogen peroxide. Other surfactants, Tween 20, Triton X-100 and Nonidet P-40, also generated γ-H2AX. These results show that γ-H2AX induction by surfactants including NPEOs, occurs via a new mechanism involving release of free DNase I with actin disruption. This mechanism is distinct from the process of γ-H2AX generation caused by direct chemically induced DNA damage. PMID:26653977

  4. Plastic mechanism of multi-pass double-roller clamping spinning for arc-shaped surface flange

    NASA Astrophysics Data System (ADS)

    Fan, Shuqin; Zhao, Shengdun; Zhang, Qi; Li, Yongyi

    2013-11-01

    Compared with the conventional single-roller spinning process, the double-roller clamping spinning(DRCS) process can effectively prevent the sheet metal surface wrinkling and improve the the production efficiency and the shape precision of final spun part. Based on ABAQUS/Explicit nonlinear finite element software, the finite element model of the multi-pass DRCS for the sheet metal is established, and the material model, the contact definition, the mesh generation, the loading trajectory and other key technical problems are solved. The simulations on the multi-pass DRCS of the ordinary Q235A steel cylindrical part with the arc-shaped surface flange are carried out. The effects of number of spinning passes on the production efficiency, the spinning moment, the shape error of the workpiece, and the wall thickness distribution of the final part are obtained. It is indicated definitely that with the increase of the number of spinning passes the geometrical precision of the spun part increases while the production efficiency reduces. Moreover, the variations of the spinning forces and the distributions of the stresses, strains, wall thickness during the multi-pass DRCS process are revealed. It is indicated that during the DRCS process the radical force is the largest, and the whole deformation area shows the tangential tensile strain and the radial compressive strain, while the thickness strain changes along the generatrix directions from the compressive strain on the outer edge of the flange to the tensile strain on the inner edge of the flange. Based on the G-CNC6135 NC lathe, the three-axis linkage computer-controlled experimental device for DRCS which is driven by the AC servo motor is developed. And then using the experimental device, the Q235A cylindrical parts with the arc-shape surface flange are formed by the DRCS. The simulation results of spun parts have good consistency with the experimental results, which verifies the feasibility of DRCS process and the

  5. A thermo-hydro-mechanical coupled model in local thermal non-equilibrium for fractured HDR reservoir with double porosity

    NASA Astrophysics Data System (ADS)

    Gelet, R.; Loret, B.; Khalili, N.

    2012-07-01

    The constitutive thermo-hydro-mechanical equations of fractured media are embodied in the theory of mixtures applied to three-phase poroelastic media. The solid skeleton contains two distinct cavities filled with the same fluid. Each of the three phases is endowed with its own temperature. The constitutive relations governing the thermomechanical behavior, generalized diffusion and transfer are structured by, and satisfy, the dissipation inequality. The cavities exchange both mass and energy. Mass exchanges are driven by the jump in scaled chemical potential, and energy exchanges by the jump in coldness. The finite element approximation uses the displacement vector, the two fluid pressures and the three temperatures as primary variables. It is used to analyze a generic hot dry rock geothermal reservoir. Three parameters of the model are calibrated from the thermal outputs of Fenton Hill and Rosemanowes HDR reservoirs. The calibrated model is next applied to simulate circulation tests at the Fenton Hill HDR reservoir. The finer thermo-hydro-mechanical response provided by the dual porosity model with respect to a single porosity model is highlighted in a parameter analysis. Emphasis is put on the influence of the fracture spacing, on the effective stress response and on the permeation of the fluid into the porous blocks. The dual porosity model yields a thermally induced effective stress that is less tensile compared with the single porosity response. This effect becomes significant for large fracture spacings. In agreement with field data, fluid loss is observed to be high initially and to decrease with time.

  6. Von Willebrand factor in patients on mechanical circulatory support – a double-edged sword between bleeding and thrombosis

    PubMed Central

    Kaczmarski, Jacek; Pacholewicz, Jerzy; Zakliczynski, Michal; Gasior, Mariusz; Zembala, Marian

    2015-01-01

    Mechanical circulatory support (MCS) is an umbrella term describing the various technologies used in both short- and long-term management of patients with either end-stage chronic heart failure (HF) or acute HF. Most often, MCS has emerged as a bridge to transplantation, but more recently it is also used as a destination therapy. Mechanical circulatory support includes left ventricular assist device (LVAD) or bi-ventricular assist device (Bi-VAD). Currently, 2- to 3-year survival in carefully selected patients is much better than with medical therapy. However, MCS therapy is hampered by sometimes life-threatening complications including bleeding and device thrombosis. Von Willebrand factor (vWF) has two major functions in haemostasis. First, it plays a crucial role in platelet-subendothelium adhesion and platelet-platelet interactions (aggregation). Second, it is the carrier of factor VIII (FVIII) in plasma. Von Willebrand factor prolongs FVIII half-time by protecting it from proteolytic degradation. It delivers FVIII to the site of vascular injury thus enhancing haemostatic process. On one hand, high plasma levels of vWF have been associated with an increased risk of thrombosis. On the other, defects or deficiencies of vWF underlie the inherited von Willebrand disease or acquired von Willebrand syndrome. Here we review the pathophysiology of thrombosis and bleeding associated with vWF. PMID:26702279

  7. 78 FR 2260 - Auction of FM Broadcast Construction Permits Rescheduled for April 23, 2013; Notice of Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-10

    ... parties submitted seven comments in response to the Auction 94 Comment Public Notice, 77 FR 60690, October... interest is non- voting. 53. In the Diversity Order, 73 FR 28400, May 16, 2008, the Commission relaxed the... From the Federal Register Online via the Government Publishing Office FEDERAL...

  8. 75 FR 28278 - Notice of amendment to Notice of Realty Action: Competitive Online Auction of Public Lands in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ..., 2009 (74 FR 46790), to add additional terms and conditions to the sale process. DATES: Interested... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE INTERIOR...: 14X5232] Notice of amendment to Notice of Realty Action: Competitive Online Auction of Public Lands...

  9. 47 CFR 27.1213 - Designated entity provisions for BRS in Commission auctions commencing prior to January 1, 2004.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., 2004 for BTA service areas are eligible for special incentives in the auction process. See 47 CFR 1... entity will have both de facto and de jure control of the entity. See 47 CFR 1.2110(i). (g) Records... COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS...

  10. 47 CFR 27.1213 - Designated entity provisions for BRS in Commission auctions commencing prior to January 1, 2004.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., 2004 for BTA service areas are eligible for special incentives in the auction process. See 47 CFR 1... entity will have both de facto and de jure control of the entity. See 47 CFR 1.2110(i). (g) Records... COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS...

  11. 75 FR 38545 - Notice of Realty Action: Competitive Auction of Public Lands in White Pine County, NV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ...: 14X5232] Notice of Realty Action: Competitive Auction of Public Lands in White Pine County, NV AGENCY... Management (BLM) proposes to offer one parcel of public land of approximately 2.5 acres in White Pine County... proposed sale of public lands until August 16, 2010. If the BLM decision is to proceed with the sale,...

  12. 40 CFR 97.721 - Recordation of TR SO2 Group 2 allowance allocations and auction results.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Recordation of TR SO2 Group 2... SO2 TRADING PROGRAMS TR SO2 Group 2 Trading Program § 97.721 Recordation of TR SO2 Group 2 allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR SO2 Group...

  13. 40 CFR 97.621 - Recordation of TR SO2 Group 1 allowance allocations and auction results.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Recordation of TR SO2 Group 1... SO2 TRADING PROGRAMS TR SO2 Group 1 Trading Program § 97.621 Recordation of TR SO2 Group 1 allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR SO2 Group...

  14. 40 CFR 97.721 - Recordation of TR SO2 Group 2 allowance allocations and auction results.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Recordation of TR SO2 Group 2... SO2 TRADING PROGRAMS TR SO2 Group 2 Trading Program § 97.721 Recordation of TR SO2 Group 2 allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR SO2 Group...

  15. 40 CFR 97.621 - Recordation of TR SO2 Group 1 allowance allocations and auction results.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Recordation of TR SO2 Group 1... SO2 TRADING PROGRAMS TR SO2 Group 1 Trading Program § 97.621 Recordation of TR SO2 Group 1 allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR SO2 Group...

  16. 40 CFR 97.621 - Recordation of TR SO2 Group 1 allowance allocations and auction results.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 22 2012-07-01 2012-07-01 false Recordation of TR SO2 Group 1... SO2 TRADING PROGRAMS TR SO2 Group 1 Trading Program § 97.621 Recordation of TR SO2 Group 1 allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR SO2 Group...

  17. 40 CFR 97.721 - Recordation of TR SO2 Group 2 allowance allocations and auction results.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Recordation of TR SO2 Group 2... SO2 TRADING PROGRAMS TR SO2 Group 2 Trading Program § 97.721 Recordation of TR SO2 Group 2 allowance allocations and auction results. (a) By November 7, 2011, the Administrator will record in each TR SO2 Group...

  18. 31 CFR 356.4 - What are the book-entry systems in which auctioned Treasury securities may be issued?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false What are the book-entry systems in which auctioned Treasury securities may be issued? 356.4 Section 356.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT SALE AND ISSUE OF...

  19. 76 FR 60830 - Auction of FM Broadcast Construction Permits Scheduled for March 27, 2012; Comment Sought on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... Competitive Bidding Procedures for Auction 93 AGENCY: Federal Communications Commission. ACTION: Notice... commence on March 27, 2012. This document also seeks comment on competitive bidding procedures for this... that FM allotment will be awarded by competitive bidding procedures. Once mutual exclusivity exists...

  20. 78 FR 50086 - Notice of Competitive Auction for Solar Energy Development on Public Lands in the State of Colorado

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... Bureau of Land Management Notice of Competitive Auction for Solar Energy Development on Public Lands in... applicant to submit a right-of-way (ROW) application and a plan of development for solar energy projects on... solicitations of interest and ROW applications within two designated Solar Energy Zones (SEZ): Los Mogotes...

  1. 47 CFR 27.1213 - Designated entity provisions for BRS in Commission auctions commencing prior to January 1, 2004.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., 2004 for BTA service areas are eligible for special incentives in the auction process. See 47 CFR 1... entity will have both de facto and de jure control of the entity. See 47 CFR 1.2110(i). (g) Records... areas in installments over a ten (10) year period running from the date that their BTA...

  2. 47 CFR 27.1213 - Designated entity provisions for BRS in Commission auctions commencing prior to January 1, 2004.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., 2004 for BTA service areas are eligible for special incentives in the auction process. See 47 CFR 1... entity will have both de facto and de jure control of the entity. See 47 CFR 1.2110(i). (g) Records... areas in installments over a ten (10) year period running from the date that their BTA...

  3. 75 FR 22792 - Closed Auction of Broadcast Construction Permits Scheduled for July 20, 2010; Notice and Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... comments and one reply comment in response to the Auction 88 Comment Public Notice, 75 FR 8070, Feb. 23... are also reminded that, by the New Entrant Bidding Credit Reconsideration Order, 64 FR 44856, Aug. 18..., even if such an interest is non-voting. 40. In the Diversity Order, 73 FR 28361, May 16, 2008,...

  4. 76 FR 21350 - Auction of 700 MHz Band Licenses Scheduled for July 19, 2011; Notice and Filing Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ..., 2011, 76 FR 1158. One party submitted comments in response to the Auction 92 Comment Public Notice, and... agreements with any individual entity for the lease or resale (including under a wholesale agreement) of, on... assignments, transfers of control, spectrum leases, or other reportable eligibility events. Rather, in...

  5. 78 FR 56875 - Tribal Mobility Fund Phase I Auction Rescheduled for December 19, 2013; Notice and Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... service support through reverse competitive bidding. The USF/ICC Transformation Order, 76 FR 73830, November 29, 2011 and 76 FR 81562, December 28, 2011, established the Mobility Fund as a universal service... program details. On March 29, 2013, the Bureaus released the Auction 902 Comment Public Notice, 78...

  6. 76 FR 3892 - Auction of FM Broadcast Construction Permits Rescheduled for April 27, 2011; Notice and Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Notice, 75 FR 61752, October 6, 2010, and two entities submitted filings by the reply comment deadline. i... auctions. J. Noncommercial Educational Status Election 66. In the NCE Second Report and Order, 68 FR 26220... From the Federal Register Online via the Government Publishing Office FEDERAL...

  7. 76 FR 78645 - Auction of FM Broadcast Construction Permits Scheduled for March 27, 2012; Notice and Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... (collectively, the Bureaus) released the Auction 93 Comment Public Notice, 76 FR 60830, September 30, 2011... applicant, even if such an interest is non-voting. 54. In the Diversity Order, 73 FR 28400, May 16, 2008... From the Federal Register Online via the Government Publishing Office ] FEDERAL...

  8. 31 CFR 356.17 - How and when do I pay for securities awarded in an auction?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false How and when do I pay for securities awarded in an auction? 356.17 Section 356.17 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE FISCAL SERVICE SALE AND ISSUE OF MARKETABLE BOOK-ENTRY...

  9. 49 CFR 599.402 - Requirements and limitations for salvage auctions that are consigned trade-in vehicles under the...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Requirements and limitations for salvage auctions that are consigned trade-in vehicles under the CARS program. 599.402 Section 599.402 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY...

  10. 77 FR 22575 - The Auction Block Company, an Alaska Corporation v. the City of Homer, a Municipal Corporation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION The Auction Block Company, an Alaska Corporation v. the City of Homer, a Municipal Corporation and Its Port of Homer; Notice of Filing of Complaint and Assignment Notice is given that a complaint has been filed with the Federal Maritime Commission...

  11. A mechanical property and stress corrosion evaluation of VIM-ESR-VAR work strengthened and direct double aged Inconel 718 bar material

    NASA Technical Reports Server (NTRS)

    Montano, J. W.

    1986-01-01

    Presented are the mechanical properties and the stress corrosion resistance of triple melted vacuum induction melted (VIM), electro-slag remelted (ESR), and vacuum arc remelted (VAR), solution treated, work strengthened and direct double aged Inconel 718 alloy bars 4.00 in. (10.16) and 5.75 in. (14.60 cm) diameter. Tensile, charpy v-notched impact, and compact tension specimens were tested at ambient temperature in both the longitudinal and transverse directions. Longitudinal tensile and yield strengths in excess of 220 ksi (1516.85 MPa) and 200 ksi (1378.00 MPa) respectively, were realized at ambient temperature. Additional charpy impact and compact tension tests were performed at -100 F (-73 C). Longitudinal charpy impact strength equalled or exceeded 12.0 ft-lbs (16.3 Joules) at ambient and at -100 F(-73 C) while longitudinal compact (LC) tension fracture toughness strength remained above 79 ksi (86.80 MPa) at ambient and at -100 F(-73 C) temperatures. No failures occurred in the longitudinal or transverse tensile specimens stressed to 75 and 100 percent of their respective yield strengths and exposed to a salt fog environment for 180 days. Tensile tests performed after the stress corrosion test indicated no mechanical property degradation.

  12. Stratification of pediatric ALL by in vitro cellular responses to DNA double-strand breaks provides insight into the molecular mechanisms underlying clinical response.

    PubMed

    Marston, Eliot; Weston, Victoria; Jesson, Jennifer; Maina, Esther; McConville, Carmel; Agathanggelou, Angelo; Skowronska, Anna; Mapp, Katie; Sameith, Katrin; Powell, Judith E; Lawson, Sarah; Kearns, Pamela; Falciani, Francesco; Taylor, Malcolm; Stankovic, Tatjana

    2009-01-01

    The molecular basis of different outcomes in pediatric acute lymphoblastic leukemia (ALL) remains poorly understood. We addressed the clinical significance and mechanisms behind in vitro cellular responses to ionizing radiation (IR)-induced DNA double-strand breaks in 74 pediatric patients with ALL. We found an apoptosis-resistant response in 36% of patients characterized by failure to cleave caspase-3, -7, -9, and PARP1 by 24 hours after IR and an apoptosis-sensitive response with the cleavage of the same substrates in the remaining 64% of leukemias. Resistance to IR in vitro was associated with poor early blast clearance at day 7 or 15 and persistent minimal residual disease (MRD) at day 28 of induction treatment. Global gene expression profiling revealed abnormal up-regulation of multiple prosurvival pathways in response to IR in apoptosis-resistant leukemias and differential posttranscriptional activation of the PI3-Akt pathway was observed in representative resistant cases. Importantly, pharmacologic inhibition of selected prosurvival pathways sensitized apoptosis-resistant ALL cells to IR in vitro. We suggest that abnormal prosurvival responses to DNA damage provide one of the mechanisms of primary resistance in ALL, and that they should be considered as therapeutic targets in children with aggressive disease. PMID:18941120

  13. MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression.

    PubMed

    Paugh, Steven W; Coss, David R; Bao, Ju; Laudermilk, Lucas T; Grace, Christy R; Ferreira, Antonio M; Waddell, M Brett; Ridout, Granger; Naeve, Deanna; Leuze, Michael; LoCascio, Philip F; Panetta, John C; Wilkinson, Mark R; Pui, Ching-Hon; Naeve, Clayton W; Uberbacher, Edward C; Bonten, Erik J; Evans, William E

    2016-02-01

    MicroRNAs are important regulators of gene expression, acting primarily by binding to sequence-specific locations on already transcribed messenger RNAs (mRNA) and typically down-regulating their stability or translation. Recent studies indicate that microRNAs may also play a role in up-regulating mRNA transcription levels, although a definitive mechanism has not been established. Double-helical DNA is capable of forming triple-helical structures through Hoogsteen and reverse Hoogsteen interactions in the major groove of the duplex, and we show physical evidence (i.e., NMR, FRET, SPR) that purine or pyrimidine-rich microRNAs of appropriate length and sequence form triple-helical structures with purine-rich sequences of duplex DNA, and identify microRNA sequences that favor triplex formation. We developed an algorithm (Trident) to search genome-wide for potential triplex-forming sites and show that several mammalian and non-mammalian genomes are enriched for strong microRNA triplex binding sites. We show that those genes containing sequences favoring microRNA triplex formation are markedly enriched (3.3 fold, p<2.2 × 10(-16)) for genes whose expression is positively correlated with expression of microRNAs targeting triplex binding sequences. This work has thus revealed a new mechanism by which microRNAs could interact with gene promoter regions to modify gene transcription. PMID:26844769

  14. A randomized, double-blind, placebo-controlled, cross-over study to evaluate analgesic activity of Terminalia chebula in healthy human volunteers using a mechanical pain model

    PubMed Central

    Pokuri, Venkata Kishan; Kumar, Chiranjeevi Uday; Pingali, Usharani

    2016-01-01

    Background and Aims: To evaluate analgesic activity and safety of single oral dose (1000 mg) of Terminalia chebula using a mechanical pain model in healthy human volunteers. Material and Methods: Twelve healthy volunteers were randomized to receive either single oral dose of 2 capsules of T. chebula 500 mg each or identical placebo capsules in a double-blinded manner. Mechanical pain was assessed using Ugo basile analgesy meter (Randall–Selitto test) before and 3 h after administration of test drug. The parameters evaluated were pain threshold force and time; pain tolerance force and time. A washout period of 1-week was given for crossover between active drug and placebo. Results: Terminalia chebula significantly increased the mean percentage change for pain threshold force and time, and pain tolerance force and time compared to placebo (P < 0.001). The mean percentage change for pain threshold force and time (20.8% and 21.0%) was increased more than that of pain tolerance force and time (13.4% and 13.4%). No adverse drug reaction was reported with either of the study medications during the study period. Conclusion: T. chebula significantly increased pain threshold and pain tolerance compared to placebo. Both the study medications were well tolerated. Further multiple dose studies may be needed to establish the analgesic efficacy of the drug in patients suffering from osteoarthritis, rheumatoid arthritis and other painful conditions. PMID:27625480

  15. MicroRNAs form triplexes with double stranded DNA at sequence-specific binding sites; a eukaryotic mechanism via which microRNAs could directly alter gene expression

    DOE PAGESBeta

    Paugh, Steven W.; Coss, David R.; Bao, Ju; Laudermilk, Lucas T.; Grace, Christy R.; Ferreira, Antonio M.; Waddell, M. Brett; Ridout, Granger; Naeve, Deanna; Leuze, Michael Rex; et al

    2016-02-04

    MicroRNAs are important regulators of gene expression, acting primarily by binding to sequence-specific locations on already transcribed messenger RNAs (mRNA). Recent studies indicate that microRNAs may also play a role in up-regulating mRNA transcription levels, although a definitive mechanism has not been established. Double-helical DNA is capable of forming triple-helical structures through Hoogsteen and reverse Hoogsteen interactions in the major groove of the duplex, and we show physical evidence that microRNAs form triple-helical structures with duplex DNA, and identify microRNA sequences that favor triplex formation. We developed an algorithm (Trident) to search genome-wide for potential triplex-forming sites and show thatmore » several mammalian and non-mammalian genomes are enriched for strong microRNA triplex binding sites. We show that those genes containing sequences favoring microRNA triplex formation are markedly enriched (3.3 fold, p<2.2 x 10-16) for genes whose expression is positively correlated with expression of microRNAs targeting triplex binding sequences. As a result, this work has thus revealed a new mechanism by which microRNAs can interact with gene promoter regions to modify gene transcription.« less

  16. Controlled synthesis and investigation of the mechanism of formation of hollow hemispherical protrusions on laurate anion-intercalated Zn/Al layered double hydroxide hybrid films.

    PubMed

    Yue, Caili; Chen, Hongyun; Xu, Sailong; Zhang, Fazhi

    2012-11-01

    Films of laurate (La) anion-intercalated zinc-aluminum layered double hydroxides (ZnAl-La-LDHs) with hollow hemispherical protrusions on the surface of the hybrid film have been conveniently prepared by an ion-exchange reaction of a nitrate-containing LDH film previously grown in situ on a porous anodic alumina/aluminum (PAO/Al) substrate. No template is required to form the hemispherical protrusions, thus avoiding a complicated template removal process. The dimensions, morphology, and resistance to bursting of the hollow hemispherical protrusions can be easily tuned by varying the experimental conditions such as sodium laurate concentration, reaction time, and reaction temperature. The evolution of the hollow protrusions was investigated by scanning electron microscopy (SEM), and a "bubble template-reconfiguration assembly" mechanism, in which air bubbles on the film surface act as a template, has been proposed to explain their formation. When the ion-exchange reaction was carried out on a film that had been treated by ultrasound to eliminate surface air bubbles, no hemispherical protrusions were formed, which is consistent with the proposed mechanism. PMID:22840873

  17. A mechanical property and stress corrosion evaluation of VIM-ESR-VAR work strengthened and direct double aged Inconel 718 bar material

    NASA Astrophysics Data System (ADS)

    Montano, J. W.

    1986-09-01

    Presented are the mechanical properties and the stress corrosion resistance of triple melted vacuum induction melted (VIM), electro-slag remelted (ESR), and vacuum arc remelted (VAR), solution treated, work strengthened and direct double aged Inconel 718 alloy bars 4.00 in. (10.16) and 5.75 in. (14.60 cm) diameter. Tensile, charpy v-notched impact, and compact tension specimens were tested at ambient temperature in both the longitudinal and transverse directions. Longitudinal tensile and yield strengths in excess of 220 ksi (1516.85 MPa) and 200 ksi (1378.00 MPa) respectively, were realized at ambient temperature. Additional charpy impact and compact tension tests were performed at -100 F (-73 C). Longitudinal charpy impact strength equalled or exceeded 12.0 ft-lbs (16.3 Joules) at ambient and at -100 F(-73 C) while longitudinal compact (LC) tension fracture toughness strength remained above 79 ksi (86.80 MPa) at ambient and at -100 F(-73 C) temperatures. No failures occurred in the longitudinal or transverse tensile specimens stressed to 75 and 100 percent of their respective yield strengths and exposed to a salt fog environment for 180 days. Tensile tests performed after the stress corrosion test indicated no mechanical property degradation.

  18. MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression

    PubMed Central

    Grace, Christy R.; Ferreira, Antonio M.; Waddell, M. Brett; Ridout, Granger; Naeve, Deanna; Leuze, Michael; LoCascio, Philip F.; Panetta, John C.; Wilkinson, Mark R.; Pui, Ching-Hon; Naeve, Clayton W.; Uberbacher, Edward C.; Bonten, Erik J.; Evans, William E.

    2016-01-01

    MicroRNAs are important regulators of gene expression, acting primarily by binding to sequence-specific locations on already transcribed messenger RNAs (mRNA) and typically down-regulating their stability or translation. Recent studies indicate that microRNAs may also play a role in up-regulating mRNA transcription levels, although a definitive mechanism has not been established. Double-helical DNA is capable of forming triple-helical structures through Hoogsteen and reverse Hoogsteen interactions in the major groove of the duplex, and we show physical evidence (i.e., NMR, FRET, SPR) that purine or pyrimidine-rich microRNAs of appropriate length and sequence form triple-helical structures with purine-rich sequences of duplex DNA, and identify microRNA sequences that favor triplex formation. We developed an algorithm (Trident) to search genome-wide for potential triplex-forming sites and show that several mammalian and non-mammalian genomes are enriched for strong microRNA triplex binding sites. We show that those genes containing sequences favoring microRNA triplex formation are markedly enriched (3.3 fold, p<2.2 × 10−16) for genes whose expression is positively correlated with expression of microRNAs targeting triplex binding sequences. This work has thus revealed a new mechanism by which microRNAs could interact with gene promoter regions to modify gene transcription. PMID:26844769

  19. Identifying Oneself with the Face of Someone Else Impairs the Egocentered Visuo-spatial Mechanisms: A New Double Mirror Paradigm to Study Self-other Distinction and Interaction.

    PubMed

    Thirioux, Bérangère; Wehrmann, Moritz; Langbour, Nicolas; Jaafari, Nematollah; Berthoz, Alain

    2016-01-01

    Looking at our face in a mirror is one of the strongest phenomenological experiences of the Self in which we need to identify the face as reflected in the mirror as belonging to us. Recent behavioral and neuroimaging studies reported that self-face identification not only relies upon visual-mnemonic representation of one's own face but also upon continuous updating and integration of visuo-tactile signals. Therefore, bodily self-consciousness plays a major role in self-face identification, with respect to interplay between unisensory and multisensory processing. However, if previous studies demonstrated that the integration of multisensory body-related signals contributes to the visual processing of one's own face, there is so far no data regarding how self-face identification, inversely, contributes to bodily self-consciousness. In the present study, we tested whether self-other face identification impacts either the egocentered or heterocentered visuo-spatial mechanisms that are core processes of bodily self-consciousness and sustain self-other distinction. For that, we developed a new paradigm, named "Double Mirror." This paradigm, consisting of a semi-transparent double mirror and computer-controlled Light Emitting Diodes, elicits self-other face merging illusory effect in ecologically more valid conditions, i.e., when participants are physically facing each other and interacting. Self-face identification was manipulated by exposing pairs of participants to an Interpersonal Visual Stimulation in which the reflection of their faces merged in the mirror. Participants simultaneously performed visuo-spatial and mental own-body transformation tasks centered on their own face (egocentered) or the face of their partner (heterocentered) in the pre- and post-stimulation phase. We show that self-other face identification altered the egocentered visuo-spatial mechanisms. Heterocentered coding was preserved. Our data suggest that changes in self-face identification induced

  20. Identifying Oneself with the Face of Someone Else Impairs the Egocentered Visuo-spatial Mechanisms: A New Double Mirror Paradigm to Study Self–other Distinction and Interaction

    PubMed Central

    Thirioux, Bérangère; Wehrmann, Moritz; Langbour, Nicolas; Jaafari, Nematollah; Berthoz, Alain

    2016-01-01

    Looking at our face in a mirror is one of the strongest phenomenological experiences of the Self in which we need to identify the face as reflected in the mirror as belonging to us. Recent behavioral and neuroimaging studies reported that self-face identification not only relies upon visual-mnemonic representation of one’s own face but also upon continuous updating and integration of visuo-tactile signals. Therefore, bodily self-consciousness plays a major role in self-face identification, with respect to interplay between unisensory and multisensory processing. However, if previous studies demonstrated that the integration of multisensory body-related signals contributes to the visual processing of one’s own face, there is so far no data regarding how self-face identification, inversely, contributes to bodily self-consciousness. In the present study, we tested whether self–other face identification impacts either the egocentered or heterocentered visuo-spatial mechanisms that are core processes of bodily self-consciousness and sustain self–other distinction. For that, we developed a new paradigm, named “Double Mirror.” This paradigm, consisting of a semi-transparent double mirror and computer-controlled Light Emitting Diodes, elicits self–other face merging illusory effect in ecologically more valid conditions, i.e., when participants are physically facing each other and interacting. Self-face identification was manipulated by exposing pairs of participants to an Interpersonal Visual Stimulation in which the reflection of their faces merged in the mirror. Participants simultaneously performed visuo-spatial and mental own-body transformation tasks centered on their own face (egocentered) or the face of their partner (heterocentered) in the pre- and post-stimulation phase. We show that self–other face identification altered the egocentered visuo-spatial mechanisms. Heterocentered coding was preserved. Our data suggest that changes in self

  1. Emerging double helical nanostructures

    NASA Astrophysics Data System (ADS)

    Zhao, Meng-Qiang; Zhang, Qiang; Tian, Gui-Li; Wei, Fei

    2014-07-01

    As one of the most important and land-mark structures found in nature, a double helix consists of two congruent single helices with the same axis or a translation along the axis. This double helical structure renders the deoxyribonucleic acid (DNA) the crucial biomolecule in evolution and metabolism. DNA-like double helical nanostructures are probably the most fantastic yet ubiquitous geometry at the nanoscale level, which are expected to exhibit exceptional and even rather different properties due to the unique organization of the two single helices and their synergistic effect. The organization of nanomaterials into double helical structures is an emerging hot topic for nanomaterials science due to their promising exceptional unique properties and applications. This review focuses on the state-of-the-art research progress for the fabrication of double-helical nanostructures based on `bottom-up' and `top-down' strategies. The relevant nanoscale, mesoscale, and macroscopic scale fabrication methods, as well as the properties of the double helical nanostructures are included. Critical perspectives are devoted to the synthesis principles and potential applications in this emerging research area. A multidisciplinary approach from the scope of nanoscience, physics, chemistry, materials, engineering, and other application areas is still required to the well-controlled and large-scale synthesis, mechanism, property, and application exploration of double helical nanostructures.

  2. Human remains sold to the highest bidder! A snapshot of the buying and selling of human skeletal remains on eBay, an Internet auction site.

    PubMed

    Huxley, Angie K; Finnegan, Michael

    2004-01-01

    Internet auction sites have become increasingly popular, with diverse items up for sale to the public worldwide. The purposes of this paper are to inform the forensic community that human skeletal remains, old and new, are for sale on the eBay internet auction site, and to advise forensic scientists that eBay does not use a forensic anthropologist to assess photographs of these materials. Over the last few years, this website was "surfed," with numerous auctions during this period. After contacting eBay by email, representatives responded that they adhere to Native American Grave Protection and Repatriation Act (NAGPRA) and that their website indicates that auctions must state that sale of human remains is for instructional purposes only. Based on the photographs, the remains appear to be of prehistoric and modern origin. An unfortunate consequence of such sale may generate interest in stealing remains from graves, mortuaries, hospitals, or county morgues worldwide. PMID:14979339

  3. The Structural Features of Thousands of T-DNA Insertion Sites Are Consistent with a Double-Strand Break Repair-Based Insertion Mechanism.

    PubMed

    Kleinboelting, Nils; Huep, Gunnar; Appelhagen, Ingo; Viehoever, Prisca; Li, Yong; Weisshaar, Bernd

    2015-11-01

    Transformation by Agrobacterium tumefaciens, an important tool in modern plant research, involves the integration of T-DNA initially present on a plasmid in agrobacteria into the genome of plant cells. The process of attachment of the agrobacteria to plant cells and the transport of T-DNA into the cell and further to the nucleus has been well described. However, the exact mechanism of integration into the host's DNA is still unclear, although several models have been proposed. During confirmation of T-DNA insertion alleles from the GABI-Kat collection of Arabidopsis thaliana mutants, we have generated about 34,000 sequences from the junctions between inserted T-DNA and adjacent genome regions. Here, we describe the evaluation of this dataset with regard to existing models for T-DNA integration. The results suggest that integration into the plant genome is mainly mediated by the endogenous plant DNA repair machinery. The observed integration events showed characteristics highly similar to those of repair sites of double-strand breaks with respect to microhomology and deletion sizes. In addition, we describe unexpected integration events, such as large deletions and inversions at the integration site that are relevant for correct interpretation of results from T-DNA insertion mutants in reverse genetics experiments. PMID:26343971

  4. Electrophoretic mobility of semi-flexible double-stranded DNA in defect-controlled polymer networks: Mechanism investigation and role of structural parameters

    NASA Astrophysics Data System (ADS)

    Khairulina, Kateryna; Li, Xiang; Nishi, Kengo; Shibayama, Mitsuhiro; Chung, Ung-il; Sakai, Takamasa

    2015-06-01

    Our previous studies have reported an empirical model, which explains the electrophoretic mobility (μ) of double-stranded DNA (dsDNA) as a combination of a basic migration term (Rouse-like or reptation) and entropy loss term in polymer gels with ideal network structure. However, this case is of exception, considering a large amount of heterogeneity in the conventional polymer gels. In this study, we systematically tune the heterogeneity in the polymer gels and study the migration of dsDNA in these gels. Our experimental data well agree with the model found for ideal networks. The basic migration mechanism (Rouse-like or reptation) persists perfectly in the conventional heterogeneous polymer gel system, while the entropy loss term continuously changes with increase in the heterogeneity. Furthermore, we found that in the limit where dsDNA is shorter than dsDNA persistence length, the entropy loss term may be related to the collisional motions between DNA fragments and the cross-links.

  5. Truthful Incentive Mechanisms for Social Cost Minimization in Mobile Crowdsourcing Systems.

    PubMed

    Duan, Zhuojun; Yan, Mingyuan; Cai, Zhipeng; Wang, Xiaoming; Han, Meng; Li, Yingshu

    2016-01-01

    With the emergence of new technologies, mobile devices are capable of undertaking computational and sensing tasks. A large number of users with these mobile devices promote the formation of the Mobile Crowdsourcing Systems (MCSs). Within a MCS, each mobile device can contribute to the crowdsourcing platform and get rewards from it. In order to achieve better performance, it is important to design a mechanism that can attract enough participants with mobile devices and then allocate the tasks among participants efficiently. In this paper, we are interested in the investigation of tasks allocation and price determination in MCSs. Two truthful auction mechanisms are proposed for different working patterns. A Vickrey-Clarke-Groves (VCG)-based auction mechanism is proposed to the continuous working pattern, and a suboptimal auction mechanism is introduced for the discontinuous working pattern. Further analysis shows that the proposed mechanisms have the properties of individual rationality and computational efficiencies. Experimental results suggest that both mechanisms guarantee all the mobile users bidding with their truthful values and the optimal maximal social cost can be achieved in the VCG-based auction mechanism. PMID:27058541

  6. Truthful Incentive Mechanisms for Social Cost Minimization in Mobile Crowdsourcing Systems

    PubMed Central

    Duan, Zhuojun; Yan, Mingyuan; Cai, Zhipeng; Wang, Xiaoming; Han, Meng; Li, Yingshu

    2016-01-01

    With the emergence of new technologies, mobile devices are capable of undertaking computational and sensing tasks. A large number of users with these mobile devices promote the formation of the Mobile Crowdsourcing Systems (MCSs). Within a MCS, each mobile device can contribute to the crowdsourcing platform and get rewards from it. In order to achieve better performance, it is important to design a mechanism that can attract enough participants with mobile devices and then allocate the tasks among participants efficiently. In this paper, we are interested in the investigation of tasks allocation and price determination in MCSs. Two truthful auction mechanisms are proposed for different working patterns. A Vickrey–Clarke–Groves (VCG)-based auction mechanism is proposed to the continuous working pattern, and a suboptimal auction mechanism is introduced for the discontinuous working pattern. Further analysis shows that the proposed mechanisms have the properties of individual rationality and computational efficiencies. Experimental results suggest that both mechanisms guarantee all the mobile users bidding with their truthful values and the optimal maximal social cost can be achieved in the VCG-based auction mechanism. PMID:27058541

  7. Effects of information on young consumers' willingness to pay for genetically modified food: experimental auction analysis.

    PubMed

    Kajale, Dilip B; Becker, T C

    2014-01-01

    This study examines the effects of information on consumers' willingness to pay (WTP) for genetically modified food (GMF). We used Vickrey second price experimental auction method for elicitation of consumer WTP for GM potato chips and GM soya-chocolate bar. The sample used in this study was university students from Delhi, India. Four information formats (positive, negative, no information, and combined information about GM technology) were used for the examination. The results show that, when students received the combine information they were willing to pay around 17%-20% premium for GMF and when received the negative information they demanded around 22% discount for GMF. While the positive- and the no-information formats alone have no considerable effect on consumers' WTP for GMF. Overall, our findings suggest that while doing marketing of GMF in India, the best strategy is to provide combined information about GM technology. PMID:24735210

  8. Double-Entry Bookkeeping.

    ERIC Educational Resources Information Center

    Snyder, Herbert

    1999-01-01

    Explains the principles and mechanics of double-entry bookkeeping as a part of the accounting cycle to produce a functioning set of accounting records. Suggests that libraries need to have accurate and timely information about their spending to gain financial control and protect against fraud and abuse. (LRW)

  9. A Good Beginning Makes a Good Market: The Effect of Different Market Opening Structures on Market Quality.

    PubMed

    Hinterleitner, Gernot; Leopold-Wildburger, Ulrike; Mestel, Roland; Palan, Stefan

    2015-01-01

    This paper deals with the market structure at the opening of the trading day and its influence on subsequent trading. We compare a single continuous double auction and two complement markets with different call auction designs as opening mechanisms in a unified experimental framework. The call auctions differ with respect to their levels of transparency. We find that a call auction not only improves market efficiency and liquidity at the beginning of the trading day when compared to the stand-alone continuous double auction, but also causes positive spillover effects on subsequent trading. Concerning the design of the opening call auction, we find no significant differences between the transparent and nontransparent specification with respect to opening prices and liquidity. In the course of subsequent continuous trading, however, market quality is slightly higher after a nontransparent call auction. PMID:26351653

  10. A Good Beginning Makes a Good Market: The Effect of Different Market Opening Structures on Market Quality

    PubMed Central

    Hinterleitner, Gernot; Leopold-Wildburger, Ulrike; Mestel, Roland; Palan, Stefan

    2015-01-01

    This paper deals with the market structure at the opening of the trading day and its influence on subsequent trading. We compare a single continuous double auction and two complement markets with different call auction designs as opening mechanisms in a unified experimental framework. The call auctions differ with respect to their levels of transparency. We find that a call auction not only improves market efficiency and liquidity at the beginning of the trading day when compared to the stand-alone continuous double auction, but also causes positive spillover effects on subsequent trading. Concerning the design of the opening call auction, we find no significant differences between the transparent and nontransparent specification with respect to opening prices and liquidity. In the course of subsequent continuous trading, however, market quality is slightly higher after a nontransparent call auction. PMID:26351653

  11. Microscopic mechanism underlying double-state lasing in an InAs/GaAs quantum dot laser diode elucidated using coupled rate equations and the spontaneous emission recorded from a window structure.

    PubMed

    Lee, J M; Jeon, B H; Kim, J; Lee, D

    2015-12-14

    We investigated the microscopic mechanism underlying the double-state lasing behavior (simultaneous lasing at the ground state [GS] and excited state [ES]) in InAs/GaAs quantum dot (QD) laser diodes. The ES and GS lasing processes that contributed to double-state lasing were examined experimentally and theoretically. Experiments were conducted in which spontaneous emission from a window of a QD laser diode was examined under lasing conditions, and numerical simulations were performed using a coupled rate equation model of the QD microstates. The findings showed that, when carrier relaxation from the ES to the GS was sufficiently slow, double-state lasing occurred. Additionally, ES lasing was found to arise not from the QD group undergoing GS lasing, but rather from another QD group in which the states were lower in energy and outside of the homogeneous bandwidth. PMID:26698961

  12. 31 CFR 356.17 - How and when do I pay for securities awarded in an auction?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false How and when do I pay for securities awarded in an auction? 356.17 Section 356.17 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT SALE AND ISSUE OF MARKETABLE BOOK-ENTRY TREASURY...

  13. Hydrothermal synthesis of a 3D double-sided comb-like ZnO nanostructure and its growth mechanism analysis.

    PubMed

    Li, Wenqiang; Gao, Shiyong; Li, Lin; Jiao, Shujie; Li, Hongtao; Wang, Jinzhong; Yu, Qingjiang; Zhang, Yong; Wang, Dongbo; Zhao, Liancheng

    2016-07-01

    Self-assembly of two-dimensional (2D) nanosheets and one-dimensional (1D) nanorods into three-dimensional (3D) double-sided comb-like ZnO nanostructures has been successfully performed via a simple one-step hydrothermal method on Si and ITO substrates. It is found that the thickness of the ZnO seeds plays a vital role in the formation of 3D double-sided comb-like ZnO. PMID:27279279

  14. Characterizing the Mechanism of Action of Double-Stranded RNA Activity against Western Corn Rootworm (Diabrotica virgifera virgifera LeConte)

    PubMed Central

    Bolognesi, Renata; Ramaseshadri, Parthasarathy; Anderson, Jerry; Bachman, Pamela; Clinton, William; Flannagan, Ronald; Ilagan, Oliver; Lawrence, Christina; Levine, Steven; Moar, William; Mueller, Geoffrey; Tan, Jianguo; Uffman, Joshua; Wiggins, Elizabeth; Heck, Gregory; Segers, Gerrit

    2012-01-01

    RNA interference (RNAi) has previously been shown to be effective in western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte) larvae via oral delivery of synthetic double-stranded RNA (dsRNA) in an artificial diet bioassay, as well as by ingestion of transgenic corn plant tissues engineered to express dsRNA. Although the RNAi machinery components appear to be conserved in Coleopteran insects, the key steps in this process have not been reported for WCR. Here we characterized the sequence of events that result in mortality after ingestion of a dsRNA designed against WCR larvae. We selected the Snf7 ortholog (DvSnf7) as the target mRNA, which encodes an essential protein involved in intracellular trafficking. Our results showed that dsRNAs greater than or equal to approximately 60 base-pairs (bp) are required for biological activity in artificial diet bioassays. Additionally, 240 bp dsRNAs containing a single 21 bp match to the target sequence were also efficacious, whereas 21 bp short interfering (si) RNAs matching the target sequence were not. This result was further investigated in WCR midgut tissues: uptake of 240 bp dsRNA was evident in WCR midgut cells while a 21 bp siRNA was not, supporting the size-activity relationship established in diet bioassays. DvSnf7 suppression was observed in a time-dependent manner with suppression at the mRNA level preceding suppression at the protein level when a 240 bp dsRNA was fed to WCR larvae. DvSnf7 suppression was shown to spread to tissues beyond the midgut within 24 h after dsRNA ingestion. These events (dsRNA uptake, target mRNA and protein suppression, systemic spreading, growth inhibition and eventual mortality) comprise the overall mechanism of action by which DvSnf7 dsRNA affects WCR via oral delivery and provides insights as to how targeted dsRNAs in general are active against insects. PMID:23071820

  15. Characterizing the mechanism of action of double-stranded RNA activity against western corn rootworm (Diabrotica virgifera virgifera LeConte).

    PubMed

    Bolognesi, Renata; Ramaseshadri, Parthasarathy; Anderson, Jerry; Bachman, Pamela; Clinton, William; Flannagan, Ronald; Ilagan, Oliver; Lawrence, Christina; Levine, Steven; Moar, William; Mueller, Geoffrey; Tan, Jianguo; Uffman, Joshua; Wiggins, Elizabeth; Heck, Gregory; Segers, Gerrit

    2012-01-01

    RNA interference (RNAi) has previously been shown to be effective in western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte) larvae via oral delivery of synthetic double-stranded RNA (dsRNA) in an artificial diet bioassay, as well as by ingestion of transgenic corn plant tissues engineered to express dsRNA. Although the RNAi machinery components appear to be conserved in Coleopteran insects, the key steps in this process have not been reported for WCR. Here we characterized the sequence of events that result in mortality after ingestion of a dsRNA designed against WCR larvae. We selected the Snf7 ortholog (DvSnf7) as the target mRNA, which encodes an essential protein involved in intracellular trafficking. Our results showed that dsRNAs greater than or equal to approximately 60 base-pairs (bp) are required for biological activity in artificial diet bioassays. Additionally, 240 bp dsRNAs containing a single 21 bp match to the target sequence were also efficacious, whereas 21 bp short interfering (si) RNAs matching the target sequence were not. This result was further investigated in WCR midgut tissues: uptake of 240 bp dsRNA was evident in WCR midgut cells while a 21 bp siRNA was not, supporting the size-activity relationship established in diet bioassays. DvSnf7 suppression was observed in a time-dependent manner with suppression at the mRNA level preceding suppression at the protein level when a 240 bp dsRNA was fed to WCR larvae. DvSnf7 suppression was shown to spread to tissues beyond the midgut within 24 h after dsRNA ingestion. These events (dsRNA uptake, target mRNA and protein suppression, systemic spreading, growth inhibition and eventual mortality) comprise the overall mechanism of action by which DvSnf7 dsRNA affects WCR via oral delivery and provides insights as to how targeted dsRNAs in general are active against insects. PMID:23071820

  16. Double Layers in Astrophysics

    NASA Technical Reports Server (NTRS)

    Williams, Alton C. (Editor); Moorehead, Tauna W. (Editor)

    1987-01-01

    Topics addressed include: laboratory double layers; ion-acoustic double layers; pumping potential wells; ion phase-space vortices; weak double layers; electric fields and double layers in plasmas; auroral double layers; double layer formation in a plasma; beamed emission from gamma-ray burst source; double layers and extragalactic jets; and electric potential between plasma sheet clouds.

  17. Reverse Auction: A Potential Strategy for Reduction of Pharmacological Therapy Cost

    PubMed Central

    Brandão, Sara Michelly Gonçalves; Issa, Victor Sarli; Ayub-Ferreira, Silvia Moreira; Storer, Samantha; Gonçalves, Bianca Gigliotti; Santos, Valter Garcia; Carvas Junior, Nelson; Guimarães, Guilherme Veiga; Bocchi, Edimar Alcides

    2015-01-01

    Background Polypharmacy is a significant economic burden. Objective We tested whether using reverse auction (RA) as compared with commercial pharmacy (CP) to purchase medicine results in lower pharmaceutical costs for heart failure (HF) and heart transplantation (HT) outpatients. Methods We compared the costs via RA versus CP in 808 HF and 147 HT patients followed from 2009 through 2011, and evaluated the influence of clinical and demographic variables on cost. Results The monthly cost per patient for HF drugs acquired via RA was $10.15 (IQ 3.51-40.22) versus $161.76 (IQ 86.05‑340.15) via CP; for HT, those costs were $393.08 (IQ 124.74-774.76) and $1,207.70 (IQ 604.48-2,499.97), respectively. Conclusion RA may reduce the cost of prescription drugs for HF and HT, potentially making HF treatment more accessible. Clinical characteristics can influence the cost and benefits of RA. RA may be a new health policy strategy to reduce costs of prescribed medications for HF and HT patients, reducing the economic burden of treatment. PMID:26200898

  18. Game auction prices are not related to biodiversity contributions of southern African ungulates and large carnivores

    PubMed Central

    Dalerum, Fredrik; Miranda, Maria

    2016-01-01

    There is an urgent need for human societies to become environmentally sustainable. Because public policy is largely driven by economic processes, quantifications of the relationship between market prices and environmental values can provide important information for developing strategies towards sustainability. Wildlife in southern Africa is often privately owned and traded at game auctions to be utilized for commercial purposes mostly related to tourism. This market offers an interesting opportunity to evaluate how market prices relate to biologically meaningful species characteristics. In this market, prices were not correlated with species contributions to either phylogenetic or functional diversity, and species contributions to phylogenetic or functional diversity did not influence the trends in prices over time for the past 20 years. Since this economic market did not seem to appreciate evolutionary or ecologically relevant characteristics, we question if the game tourism market may contribute towards biodiversity conservation in southern Africa. We suggest that market prices in general may have limited values as guides for directing conservation and environmental management. We further suggest that there is a need to evaluate what humans value in biological organisms, and how potentially necessary shifts in such values can be instigated. PMID:26911226

  19. Game auction prices are not related to biodiversity contributions of southern African ungulates and large carnivores.

    PubMed

    Dalerum, Fredrik; Miranda, Maria

    2016-01-01

    There is an urgent need for human societies to become environmentally sustainable. Because public policy is largely driven by economic processes, quantifications of the relationship between market prices and environmental values can provide important information for developing strategies towards sustainability. Wildlife in southern Africa is often privately owned and traded at game auctions to be utilized for commercial purposes mostly related to tourism. This market offers an interesting opportunity to evaluate how market prices relate to biologically meaningful species characteristics. In this market, prices were not correlated with species contributions to either phylogenetic or functional diversity, and species contributions to phylogenetic or functional diversity did not influence the trends in prices over time for the past 20 years. Since this economic market did not seem to appreciate evolutionary or ecologically relevant characteristics, we question if the game tourism market may contribute towards biodiversity conservation in southern Africa. We suggest that market prices in general may have limited values as guides for directing conservation and environmental management. We further suggest that there is a need to evaluate what humans value in biological organisms, and how potentially necessary shifts in such values can be instigated. PMID:26911226

  20. Estimating the impact of different cigarette package warning label policies: the auction method.

    PubMed

    Thrasher, James F; Rousu, Matthew C; Anaya-Ocampo, Rafael; Reynales-Shigematsu, Luz Myriam; Arillo-Santillán, Edna; Hernández-Avila, Mauricio

    2007-12-01

    The study estimated the reduction in demand associated with implementing cigarette package warning labels that contain imagery illustrating the consequences of smoking. The experimental auction method was used, wherein adult smokers in Mexico (n=89) placed separate bids on two packs of cigarettes: one with a text-only warning label and the other with a warning label that included text and a graphic image. Differences in the values attributed to each pack were assessed using t-tests and multivariate regression. The pack with the graphic image had a mean attributed value which was 17% lower ($3.21 pesos) than the pack with the text-only warning, and this difference remained statistically significant within subgroups defined by sociodemographics, amount of smoking, number of quit attempts, and levels of perceived smoking risks. In the multivariate model, the difference in attributed values was greater among females than males, but no such differences were found for other sociodemographic or smoking-related variables. The consistently lower value that smokers attributed to cigarette packages with the graphic warning label indicates that these labels are likely to reduce cigarette demand. PMID:17630221

  1. Experimental study of a mechanically ventilated double-skin facade with venetian sun-shading device: A full-scale investigation in controlled environment

    SciTech Connect

    Gavan, Valentin; Woloszyn, Monika; Kuznik, Frederic; Roux, Jean-Jacques

    2010-02-15

    The aim of this article is to present results of an experimental campaign performed on a full-scale facility provided with a double-skin facade. The behaviour of this architectural concept is tested under controlled climatic conditions. A summer case is scrutinised under different configurations: variation of the airflow through the double-skin facade and different angle of the solar shading device. This paper describes the experimental conditions, as well the test facility and the tested facade element. The results show the temperatures of the test cell and the facade and how they depend on the climatic conditions and the sun-shading device blade angles. One objective of this research was to measure and provide extensive data set detailing air and surface temperatures on the double-skin facade, together with airflow rates and air velocities. The experiments are fully described so that the results can be used for the validation of numerical models dealing with ventilated double-skin facades with venetian sun-shading device. (author)

  2. Usefulness of extracorporeal membrane oxygenation using double roller pumps in a low body weight newborn: A novel strategy for mechanical circulatory support in an infant.

    PubMed

    Nakanishi, Keisuke; Kato, Tomoko; Kawasaki, Shiori; Amano, Atsushi

    2016-01-01

    Extracorporeal membrane oxygenation (ECMO) with a centrifugal pump requires a certain flow rate; therefore, its application for low body weight infants is frequently accompanied by oxygenator membrane malfunction and/or inadequate perfusion. To prevent low-flow associated complications, we report a case in which a novel system of dual roller pumps was used. A baby girl with a body mass index 0.25 m(2), who experienced difficulty weaning from cardiopulmonary bypass after a Norwood-like operation, required an ECMO. Concerns for the tube lifespan reduction due to roller pump friction led to the use of a double roller pump circulation. The termination of ECMO during tube exchange is not needed, because circulation is maintained by another roller pump. The novel strategy of ECMO with double roller pumps will allow low perfusion rate to provide adequate circulatory support for low body weight patients. PMID:27011702

  3. Usefulness of extracorporeal membrane oxygenation using double roller pumps in a low body weight newborn: A novel strategy for mechanical circulatory support in an infant

    PubMed Central

    Nakanishi, Keisuke; Kato, Tomoko; Kawasaki, Shiori; Amano, Atsushi

    2016-01-01

    Extracorporeal membrane oxygenation (ECMO) with a centrifugal pump requires a certain flow rate; therefore, its application for low body weight infants is frequently accompanied by oxygenator membrane malfunction and/or inadequate perfusion. To prevent low-flow associated complications, we report a case in which a novel system of dual roller pumps was used. A baby girl with a body mass index 0.25 m2, who experienced difficulty weaning from cardiopulmonary bypass after a Norwood-like operation, required an ECMO. Concerns for the tube lifespan reduction due to roller pump friction led to the use of a double roller pump circulation. The termination of ECMO during tube exchange is not needed, because circulation is maintained by another roller pump. The novel strategy of ECMO with double roller pumps will allow low perfusion rate to provide adequate circulatory support for low body weight patients. PMID:27011702

  4. ELECTROMAGNETISM, OPTICS, ACOUSTICS, HEAT TRANSFER, CLASSICAL MECHANICS, AND FLUID DYNAMICS: Double Symplectic Eigenfunction Expansion Method of Free Vibration of Rectangular Thin Plates

    NASA Astrophysics Data System (ADS)

    Wang, Hua; Alatancang; Huang, Jun-Jie

    2009-12-01

    The free vibration problem of rectangular thin plates is rewritten as a new upper triangular matrix differential system. For the associated operator matrix, we find that the two diagonal block operators are Hamiltonian. Moreover, the existence and completeness of normed symplectic orthogonal eigenfunction systems of these two block operators are demonstrated. Based on the completeness, the general solution of the free vibration of rectangular thin plates is given by double symplectic eigenfunction expansion method.

  5. Factors affecting the selling price of feeder cattle sold at Arkansas livestock auctions in 2005.

    PubMed

    Barham, B L; Troxel, T R

    2007-12-01

    Data were collected from 15 Arkansas livestock auctions to determine factors affecting selling price. Data included how calves were sold (single or groups), sex, breed or breed type, color, muscle thickness, horn status, frame score, fill, body condition, age, health, BW, and price. Data were randomly collected on 52,401 lots consisting of 105,542 calves. Selling prices for steers ($124.20 +/- 0.07), bulls ($117.93 +/- 0.12), and heifers ($112.81 +/- 0.07) were different from each other (P <0.001). Hereford x Charolais feeder calves sold for the highest price ($122.66 +/- 0.14) and Longhorns sold for the lowest price ($74.52 +/- 0.46). Yellow feeder cattle received the highest selling price ($96.47 +/- 0.12), and spotted or striped feeder cattle received the lowest price ($83.84 +/- 0.23). The selling price of singles was lower than the price for calves sold in groups of 6 or more ($117.26 +/- 0.06 vs. $122.61 +/- 0.21; P <0.001). For cattle classified as having muscle scores of 1, 2, 3, and 4, selling prices were $120.45 +/- 0.05, $111.31 +/- 0.09, $96.28 +/- 0.44, and $82.21 +/- 1.87, respectively. Polled feeder cattle sold for $118.57 +/- 0.05, and horned feeder cattle sold for $114.87 +/- 0.14 (P <0.001). Interactions (P <0.001) were detected between frame score and BW groups, and muscle score and BW groups on the selling price of cattle. A number of management and genetic factors affected the selling price of feeder cattle. PMID:17709785

  6. Measuring the Double Helix

    SciTech Connect

    Mathew-Fenn, R.S.; Das, R.; Harbury, P.A.B.

    2009-05-26

    DNA is thought to behave as a stiff elastic rod with respect to the ubiquitous mechanical deformations inherent to its biology. To test this model at short DNA lengths, we measured the mean and variance of end-to-end length for a series of DNA double helices in solution, using small-angle x-ray scattering interference between gold nanocrystal labels. In the absence of applied tension, DNA is at least one order of magnitude softer than measured by single-molecule stretching experiments. Further, the data rule out the conventional elastic rod model. The variance in end-to-end length follows a quadratic dependence on the number of base pairs rather than the expected linear dependence, indicating that DNA stretching is cooperative over more than two turns of the DNA double helix. Our observations support the idea of long-range allosteric communication through DNA structure.

  7. ELECTROMAGNETISM, OPTICS, ACOUSTICS, HEAT TRANSFER, CLASSICAL MECHANICS, AND FLUID DYNAMICS: Ultraslow Optical Solitons in a Coupled Double Quantum-Well Nanostructure

    NASA Astrophysics Data System (ADS)

    Hao, Xiang-Ying; Liu, Ji-Bing; Lü, Xin-You; Song, Pei-Jun; Si, Liu-Gang

    2009-03-01

    We demonstrate the formation of ultraslow dark optical solitons with a four-level scheme in an asymmetric semiconductor double quantum well (SDQW) structure based on intersubband transitions by using only a low-intensity pulsed laser radiation. With appropriate conditions we show numerically that the dark optical soliton can travel with a ultraslow group velocity Vg/c ~ - 10-3. Such a semiconductor system is much more practical than its atomic counterpart because of its flexible design and the controllable interference strength. This nonlinear optical process in the SDQW solid-state material may be used for the control technology of optical delay lines and optical buffers.

  8. ELECTROMAGNETISM, OPTICS, ACOUSTICS, HEAT TRANSFER, CLASSICAL MECHANICS, AND FLUID DYNAMICS: Selective Deflection of Polarized Light Via Coherently Driven Four-Level Atoms in a Double-Λ Configuration

    NASA Astrophysics Data System (ADS)

    Guo, Yu

    2010-05-01

    We study the interaction of a weak probe field, having two circular polarized components, i.e., σ- and σ+ polarization, with an optically dense medium of four-level atoms in a double-Λ configuration, which is mediated by the electromagnetically induced transparency with a polarized control light with spatially inhomogeneous profile. We analyse the deflection of the polarized probe light and we find that we can selectively determine which circular component will be deflected after the polarized probe light enters the atom medium via adjusting the polarization and detuning of the control field.

  9. A revealed preference approach to estimating supply curves for ecosystem services: use of auctions to set payments for soil erosion control in Indonesia.

    PubMed

    Jack, B Kelsey; Leimona, Beria; Ferraro, Paul J

    2009-04-01

    To supply ecosystem services, private landholders incur costs. Knowledge of these costs is critical for the design of conservation-payment programs. Estimating these costs accurately is difficult because the minimum acceptable payment to a potential supplier is private information. We describe how an auction of payment contracts can be designed to elicit this information during the design phase of a conservation-payment program. With an estimate of the ecosystem-service supply curve from a pilot auction, conservation planners can explore the financial, ecological, and socioeconomic consequences of alternative scaled-up programs. We demonstrate the potential of our approach in Indonesia, where soil erosion on coffee farms generates downstream ecological and economic costs. Bid data from a small-scale, uniform-price auction for soil-conservation contracts allowed estimates of the costs of a scaled-up program, the gain from integrating biophysical and economic data to target contracts, and the trade-offs between poverty alleviation and supply of ecosystem services. Our study illustrates an auction-based approach to revealing private information about the costs of supplying ecosystem services. Such information can improve the design of programs devised to protect and enhance ecosystem services. PMID:18983597

  10. 31 CFR 356.4 - What are the book-entry systems in which auctioned Treasury securities may be issued or maintained?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false What are the book-entry systems in... BUREAU OF THE PUBLIC DEBT SALE AND ISSUE OF MARKETABLE BOOK-ENTRY TREASURY BILLS, NOTES, AND BONDS... book-entry systems in which auctioned Treasury securities may be issued or maintained? There are...

  11. 31 CFR 356.4 - What are the book-entry systems in which auctioned Treasury securities may be issued or maintained?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false What are the book-entry systems in which auctioned Treasury securities may be issued or maintained? 356.4 Section 356.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE...

  12. 31 CFR 356.4 - What are the book-entry systems in which auctioned Treasury securities may be issued or maintained?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false What are the book-entry systems in which auctioned Treasury securities may be issued or maintained? 356.4 Section 356.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE...

  13. 31 CFR 356.4 - What are the book-entry systems in which auctioned Treasury securities may be issued or maintained?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false What are the book-entry systems in which auctioned Treasury securities may be issued or maintained? 356.4 Section 356.4 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE...

  14. Do I hear... anyone here? Tax-exempt healthcare facilities have taken a hit on auction-rate securities as the mortgage meltdown has investors skittish.

    PubMed

    Evans, Melanie

    2008-02-25

    The crisis in auction-rate securities is coming down hard on tax-exempt providers. Buyers are disappearing, sending interest rates soaring. Some hospitals and other healthcare borrowers are being forced to pay maximum interest. "Basically, the investor pool has all but vanished," says Melissa Williams, left, of Christus Health. PMID:18491765

  15. 78 FR 65982 - Auction of H Block Licenses in the 1915-1920 MHz and 1995-2000 MHz Bands Rescheduled for January...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ... Comment Public Notice, 78 FR 45524, July 29, 2013. B. Description of Licenses To Be Offered in Auction 96 4. In the H Block Report and Order, 78 FR 50213, August 16, 2013, the Commission concluded that... From the Federal Register Online via the Government Publishing Office FEDERAL...

  16. A Virtual Field Trip to the Real World of Cap and Trade: Environmental Economics and the EPA SO[subscript 2] Allowance Auction

    ERIC Educational Resources Information Center

    Lewis, Lynne Y.

    2011-01-01

    In the spring of 2001, Bates College Environmental Economics classes bought their first sulfur dioxide emissions allowance at U.S. Environmental Protection Agency's annual auction, then conducted by the Chicago Board of Trade. In the spring of 2010, they bought their 22nd through 34th allowances. This article describes a three-part method for…

  17. Lubrication performance and mechanisms of Mg/Al-, Zn/Al-, and Zn/Mg/Al-layered double hydroxide nanoparticles as lubricant additives

    NASA Astrophysics Data System (ADS)

    Li, Shuo; Bhushan, Bharat

    2016-08-01

    Solid lubricant particles are commonly used as oil additives for low friction and wear. Mg/Al-, Zn/Al-, and Zn/Mg/Al-layered double hydroxides (LDH) were synthesized by coprecipitation method. The benefits of LDH nanoparticles are that they can be synthesized using chemical methods where size and shape can be controlled, and can be modified organically to allow dispersal in fluids. The LDH nanoparticles were characterized by X-ray diffraction, scanning electron microscope, thermogravimetry, and differential scanning calorimetry. A pin-on-disk friction and wear tester was used for evaluating the friction and wear properties of LDH nanoparticles as lubricant additives. LDH nanoparticles have friction-reducing and anti-wear properties compared to oil without LDHs. Mg/Al-LDH has the best lubrication, possibly due to better thermal stability in severe conditions.

  18. Possible interstellar formation of glycine through a concerted mechanism: a computational study on the reaction of CH2[double bond, length as m-dash]NH, CO2 and H2.

    PubMed

    Nhlabatsi, Zanele P; Bhasi, Priya; Sitha, Sanyasi

    2016-07-27

    Glycine being the simplest amino acid and also having significant astrobiological implications, has meant that intensive investigations have been carried out in the past, starting from its detection in the interstellar medium (ISM) to analysis of meteorites and cometary samples and laboratory synthesis, as well as computational studies on the possible reaction paths. In this present work quantum chemical calculations have been performed to investigate the possible interstellar formation of glycine via two different paths; (1) in a two-step process via a dihydroxy carbene intermediate and (2) through a one-step concerted mechanism, starting from reactants like CH2[double bond, length as m-dash]NH, CO, CO2, H2O and H2. For the two reactions representing the carbene route, it was observed that the formation of dihydroxy carbene from either CO + H2O or CO2 + H2 is highly endothermic with large barrier heights, whereas the subsequent step of interaction of this carbene with CH2[double bond, length as m-dash]NH to give glycine is exothermic and the barrier is below the reactants. Based on this observation it is suggested that the formation of glycine via the carbene route is a least favourable or even unfavourable path. On the other hand, the two reactions CH2[double bond, length as m-dash]NH + CO + H2O and CH2[double bond, length as m-dash]NH + CO2 + H2 representing the concerted paths were found to be favourable in leading to the formation of glycine. After an extensive study on the first concerted reaction in our previous work (Phys. Chem. Chem. Phys., 2016, 18, 375-381), in this work a detailed investigation has been carried out for the second concerted reaction, CH2[double bond, length as m-dash]NH + CO2 + H2, which can possibly lead to the interstellar formation of glycine. It was observed that this reaction proceeds through a large barrier and at the same time the transition state shows prominent hydrogen dynamics, indicating a tunnelling possibility for this

  19. Target Tracking via Crowdsourcing: A Mechanism Design Approach

    NASA Astrophysics Data System (ADS)

    Cao, Nianxia; Brahma, Swastik; Varshney, Pramod K.

    2015-03-01

    In this paper, we propose a crowdsourcing based framework for myopic target tracking by designing an incentive-compatible mechanism based optimal auction in a wireless sensor network (WSN) containing sensors that are selfish and profit-motivated. For typical WSNs which have limited bandwidth, the fusion center (FC) has to distribute the total number of bits that can be transmitted from the sensors to the FC among the sensors. To accomplish the task, the FC conducts an auction by soliciting bids from the selfish sensors, which reflect how much they value their energy cost. Furthermore, the rationality and truthfulness of the sensors are guaranteed in our model. The final problem is formulated as a multiple-choice knapsack problem (MCKP), which is solved by the dynamic programming method in pseudo-polynomial time. Simulation results show the effectiveness of our proposed approach in terms of both the tracking performance and lifetime of the sensor network.

  20. Seeing Double

    NASA Astrophysics Data System (ADS)

    Pesic, Peter

    2003-10-01

    The separateness and connection of individuals is perhaps the central question of human life: What, exactly, is my individuality? To what degree is it unique? To what degree can it be shared, and how? To the many philosophical and literary speculations about these topics over time, modern science has added the curious twist of quantum theory, which requires that the elementary particles of which everything consists have no individuality at all. All aspects of chemistry depend on this lack of individuality, as do many branches of physics. From where, then, does our individuality come? In Seeing Double, Peter Pesic invites readers to explore this intriguing set of questions. He draws on literary and historical examples that open the mind (from Homer to Martin Guerre to Kafka), philosophical analyses that have helped to make our thinking and speech more precise, and scientific work that has enabled us to characterize the phenomena of nature. Though he does not try to be all-inclusive, Pesic presents a broad range of ideas, building toward a specific point of view: that the crux of modern quantum theory is its clash with our ordinary concept of individuality. This represents a departure from the usual understanding of quantum theory. Pesic argues that what is bizarre about quantum theory becomes more intelligible as we reconsider what we mean by individuality and identity in ordinary experience. In turn, quantum identity opens a new perspective on us. Peter Pesic is a Tutor and Musician-in-Residence at St. John's College, Santa Fe, New Mexico. He has a Ph.D. in physics from Stanford University.

  1. Double inflation

    SciTech Connect

    Silk, J.; Turner, M.S.

    1986-04-01

    The Zel'dovich spectrum of adiabatic density perturbations is a generic prediction of inflation. There is increasing evidence that when the spectrum is normalized by observational data on small scales, there is not enough power on large scales to account for the observed large-scale structure in the Universe. Decoupling the spectrum on large and small scales could solve this problem. As a means of decoupling the large and small scales we propose double inflation (i.e., two episodes of inflation). In this scenario the spectrum on large scales is determined by the first episode of inflation and those on small scales by a second episode of inflation. We present three models for such a scenario. By nearly saturating the large angular-scale cosmic microwave anisotropy bound, we can easily account for the observed large-scale structure. We take the perturbations on small scales to be very large, deltarho/rho approx. = 0.1 to 0.01, which results in the production of primordial black holes (PBHs), early formation of structure, reionization of the Universe, and a rich array of astrophysical events. The ..cap omega..-problem is also addressed by our scenario. Allowing the density perturbations produced by the second episode of inflation to be large also lessens the fine-tuning required in the scalar potential and makes reheating much easier. We briefly speculate on the possibility that the second episode of inflation proceeds through the nucleation of bubbles, which today manifest themselves as empty bubbles whose surfaces are covered with galaxies. 37 refs., 1 fig.

  2. Colloidal Double Quantum Dots

    PubMed Central

    2016-01-01

    Conspectus Pairs of coupled quantum dots with controlled coupling between the two potential wells serve as an extremely rich system, exhibiting a plethora of optical phenomena that do not exist in each of the isolated constituent dots. Over the past decade, coupled quantum systems have been under extensive study in the context of epitaxially grown quantum dots (QDs), but only a handful of examples have been reported with colloidal QDs. This is mostly due to the difficulties in controllably growing nanoparticles that encapsulate within them two dots separated by an energetic barrier via colloidal synthesis methods. Recent advances in colloidal synthesis methods have enabled the first clear demonstrations of colloidal double quantum dots and allowed for the first exploratory studies into their optical properties. Nevertheless, colloidal double QDs can offer an extended level of structural manipulation that allows not only for a broader range of materials to be used as compared with epitaxially grown counterparts but also for more complex control over the coupling mechanisms and coupling strength between two spatially separated quantum dots. The photophysics of these nanostructures is governed by the balance between two coupling mechanisms. The first is via dipole–dipole interactions between the two constituent components, leading to energy transfer between them. The second is associated with overlap of excited carrier wave functions, leading to charge transfer and multicarrier interactions between the two components. The magnitude of the coupling between the two subcomponents is determined by the detailed potential landscape within the nanocrystals (NCs). One of the hallmarks of double QDs is the observation of dual-color emission from a single nanoparticle, which allows for detailed spectroscopy of their properties down to the single particle level. Furthermore, rational design of the two coupled subsystems enables one to tune the emission statistics from single

  3. Colloidal Double Quantum Dots.

    PubMed

    Teitelboim, Ayelet; Meir, Noga; Kazes, Miri; Oron, Dan

    2016-05-17

    Pairs of coupled quantum dots with controlled coupling between the two potential wells serve as an extremely rich system, exhibiting a plethora of optical phenomena that do not exist in each of the isolated constituent dots. Over the past decade, coupled quantum systems have been under extensive study in the context of epitaxially grown quantum dots (QDs), but only a handful of examples have been reported with colloidal QDs. This is mostly due to the difficulties in controllably growing nanoparticles that encapsulate within them two dots separated by an energetic barrier via colloidal synthesis methods. Recent advances in colloidal synthesis methods have enabled the first clear demonstrations of colloidal double quantum dots and allowed for the first exploratory studies into their optical properties. Nevertheless, colloidal double QDs can offer an extended level of structural manipulation that allows not only for a broader range of materials to be used as compared with epitaxially grown counterparts but also for more complex control over the coupling mechanisms and coupling strength between two spatially separated quantum dots. The photophysics of these nanostructures is governed by the balance between two coupling mechanisms. The first is via dipole-dipole interactions between the two constituent components, leading to energy transfer between them. The second is associated with overlap of excited carrier wave functions, leading to charge transfer and multicarrier interactions between the two components. The magnitude of the coupling between the two subcomponents is determined by the detailed potential landscape within the nanocrystals (NCs). One of the hallmarks of double QDs is the observation of dual-color emission from a single nanoparticle, which allows for detailed spectroscopy of their properties down to the single particle level. Furthermore, rational design of the two coupled subsystems enables one to tune the emission statistics from single photon

  4. Fabrication of mechanically robust, self-cleaning and optically high-performance hybrid thin films by SiO₂&TiO₂ double-shelled hollow nanospheres.

    PubMed

    Yao, Lin; He, Junhui; Geng, Zhi; Ren, Tingting

    2015-08-14

    Low-cost antireflection (AR) thin films on large-area optical surfaces are important for high-performance optical devices, display devices and photovoltaic cells. In the current work, SiO2&TiO2 double-shell hollow nanospheres (DSHNs) were designed, synthesized and utilized as building blocks for fabricating multifunctional AR thin films. By optimizing the porosity of SiO2&TiO2 DSHN and thin film structure, substrates with DSHN thin films attained transmittance as high as 99.4% and average transmittance up to 98.5% in the visible region. The nano-composite SiO2-TiO2 films exhibited intrinsic superhydrophilicity, anti-fogging and high photocatalytic activity. Tape peeling test, sponge washing test, and high temperature and moisture proof test showed favorable robustness and functional durability of the thin films, which make them extremely attractive for applications in lenses, photovoltaic cells and windows of high-rise buildings. PMID:26176362

  5. Generation and transportation mechanisms for two-dimensional hole gases in GaN/AlGaN/GaN double heterostructures

    SciTech Connect

    Nakajima, Akira Ogura, Masahiko; Makino, Toshiharu; Nishizawa, Shin-ichi; Ohashi, Hiromichi; Yamasaki, Satoshi; Liu, Pucheng; Kakushima, Kuniyuki; Iwai, Hiroshi

    2014-04-21

    The electrical properties of two-dimensional hole gases (2DHGs) in GaN/AlGaN/GaN double heterostructures were investigated. The layers were grown on sapphire substrates and a high-quality bulk GaN substrate. The coexistence of 2DHG and 2D electron gases on both sides of the AlGaN layer was confirmed by Hall effect measurements at 80–460 K. It was also verified that the 2DHGs were generated by negative polarization at the undoped GaN/AlGaN interface, which did not have a doped Mg acceptor. It was also demonstrated that the 2DHG density could be controlled by varying the AlGaN layer thickness and was inversely related to the 2DHG mobility. The measured relation indicated that the 2DHG mobility is mainly limited by phonon scatterings at around room temperature. As a result, the maximum 2DHG mobility of 16 cm{sup 2}/Vs at 300 K was achieved with a density of 1 × 10{sup 13} cm{sup −2}.

  6. Effect of amino acid dopants on the spectral, optical, mechanical and thermal properties of potassium acid phthalate crystals for possible optoelectronic and frequency doubling applications

    NASA Astrophysics Data System (ADS)

    Prakash, J. Thomas Joseph; Gnanaraj, J. Martin Sam; Dhavud, S. Shek; Ekadevasena, S.

    2015-09-01

    Undoped and amino acid (L-Arginine and L-Valine) doped KAP crystals were grown by slow evaporation solution growth technique. The changes in the structural, spectral, optical, mechanical and thermal properties were observed. The sharp prominent peaks in the indexed powder XRD pattern confirms the crystalline nature of the sample. Optical studies reveal that the crystal is transparent in the entire visible light region. Thermal stability was checked by TG/DTA analysis. The mechanical stability was evaluated from Vicker's microhardness test. The SHG efficiency for the title materials was tested with different particle sizes by the Kurtz and Perry powder method, which established the existence of phase matching.

  7. Biphoton double-slit experiment

    SciTech Connect

    Brida, G.; Cagliero, E.; Falzetta, G.; Genovese, M.; Gramegna, M.; Predazzi, E.

    2003-09-01

    In this paper we present a double-slit experiment where two indistinguishable photons produced by type-I parametric down-conversion are each sent to a well-defined slit. Data about the diffraction and interference patterns for coincidences are presented and discussed. An analysis of these data allows a test of standard quantum mechanics against the de Broglie-Bohm theory.

  8. Mechanisms Regulating Insulin Response to Intragastric Glucose in Lean and Non-Diabetic Obese Subjects: A Randomized, Double-Blind, Parallel-Group Trial

    PubMed Central

    Meyer-Gerspach, Anne Christin; Cajacob, Lucian; Riva, Daniele; Herzog, Raphael; Drewe, Juergen; Beglinger, Christoph; Wölnerhanssen, Bettina K.

    2016-01-01

    Background/Objectives The changes in blood glucose concentrations that result from an oral glucose challenge are dependent on the rate of gastric emptying, the rate of glucose absorption and the rate of insulin-driven metabolism that include the incretins, glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1). The rate of insulin-driven metabolism is clearly altered in obese subjects, but it is controversial which of these factors is predominant. We aimed to quantify gastric emptying, plasma insulin, C-peptide, glucagon and glucose responses, as well as incretin hormone secretions in obese subjects and healthy controls during increasing glucose loads. Subjects/Methods The study was conducted as a randomized, double-blind, parallel-group trial in a hospital research unit. A total of 12 normal weight (6 men and 6 women) and 12 non-diabetic obese (BMI > 30, 6 men and 6 women) participants took part in the study. Subjects received intragastric loads of 10 g, 25 g and 75 g glucose dissolved in 300 ml tap water. Results Main outcome measures were plasma GLP-1 and GIP, plasma glucagon, glucose, insulin, C-peptide and gastric emptying. The primary findings are: i) insulin resistance (P < 0.001) and hyperinsulinemia (P < 0.001); ii) decreased insulin disposal (P < 0.001); iii) trend for reduced GLP-1 responses at 75 g glucose; and iv) increased fasting glucagon levels (P < 0.001) in obese subjects. Conclusions It seems that, rather than changes in incretin secretion, fasting hyperglucagonemia and consequent hyperglycemia play a role in reduced disposal of insulin, contributing to hyperinsulinemia and insulin resistance. Trial Registration ClinicalTrials.gov NCT01875575 PMID:26942445

  9. The double loop mattress suture

    PubMed Central

    Biddlestone, John; Samuel, Madan; Creagh, Terry; Ahmad, Tariq

    2014-01-01

    An interrupted stitch type with favorable tissue characteristics will reduce local wound complications. We describe a novel high-strength, low-tension repair for the interrupted closure of skin, cartilage, and muscle, the double loop mattress stitch, and compare it experimentally with other interrupted closure methods. The performance of the double loop mattress technique in porcine cartilage and skeletal muscle is compared with the simple, mattress, and loop mattress interrupted sutures in both a novel porcine loading chamber and mechanical model. Wound apposition is assessed by electron microscopy. The performance of the double loop mattress in vivo was confirmed using a series of 805 pediatric laparotomies/laparoscopies. The double loop mattress suture is 3.5 times stronger than the loop mattress in muscle and 1.6 times stronger in cartilage (p ≤ 0.001). Additionally, the double loop mattress reduces tissue tension by 66% compared with just 53% for the loop mattress (p ≤ 0.001). Wound gapping is equal, and wound eversion appears significantly improved (p ≤ 0.001) compared with the loop mattress in vitro. In vivo, the double loop mattress performs as well as the loop mattress and significantly better than the mattress stitch in assessments of wound eversion and dehiscence. There were no episodes of stitch extrusion in our series of patients. The mechanical advantage of its intrinsic pulley arrangement gives the double loop mattress its favorable properties. Wound dehiscence is reduced because this stitch type is stronger and exerts less tension on the tissue than the mattress stitch. We advocate the use of this novel stitch wherever a high-strength, low-tension repair is required. These properties will enhance wound repair, and its application will be useful to surgeons of all disciplines. PMID:24698436

  10. [The application of n-acetylcysteine as an antioxidant and mucolytic in mechanical ventilation in intensive care patients. A prospective, randomized, placebo-controlled, double-blind study].

    PubMed

    Konrad, F; Schoenberg, M H; Wiedmann, H; Kilian, J; Georgieff, M

    1995-09-01

    Oxygen radicals and oxygen radial mediators are thought to be important components in the development of acute lung injury, sepsis, and multiple organ failure. Injured patients, patients with pulmonary diseases, and multiple trauma patients also showed an elevated lipid peroxidation, indicating increased oxidant stress. N-Acetylcysteine (NAC) has been used as an antioxidant in a wide variety of experiments. NAC has been suggested to act by raising concentrations of cysteine, and hence glutathione, and by scavenging of oxidant species [1, 11, 17, 29]. The present study was designed to investigate whether the application of NAC in intubated patients has an effect on concentrations of reduced glutathione in plasma and bronchoalveolar lavage fluid (BAL) and on the lipid peroxidation products malondialdehyde and conjugated dienes. Because NAC has been widely used as a mucolytic drug for the treatment of lung diseases, the influence on tracheobronchial mucus was studied, too. METHODS. In a randomized, double-blind, placebo-controlled study, a total of 38 long-term ventilated patients of a surgical intensive care unit were investigated. Patients were treated for 5 days with either 3 g NAC/day or placebo. The plasma concentration of reduced glutathione, malondialdehyde, and conjugated dienes were measured on admission and on the 3rd and 5th days of treatment [8, 34, 48]. Additionally, the numbers of tracheobronchial suctionings were registered and chest radiographs were evaluated. A fibre-bronchoscopy was performed on admission and on the 3rd day of treatment. The amount and viscidity of tracheobronchial secretions were examined semiquantitatively, and glutathione levels were measured in the unconcentrated BAL. The study was approved by the ethics committee of the University of Ulm. RESULTS. The two groups were comparable with respect to age, sex, APACHE II score and diagnosis (Table 1). We found no significant differences in reduced glutathione levels in the plasma or in

  11. Mechanism of action studies of lomaiviticin A and the monomeric lomaiviticin aglycon. Selective and potent activity toward DNA double-strand break repair-deficient cell lines.

    PubMed

    Colis, Laureen C; Hegan, Denise C; Kaneko, Miho; Glazer, Peter M; Herzon, Seth B

    2015-05-01

    (-)-Lomaiviticin A (1) and the monomeric lomaiviticin aglycon [aka: (-)-MK7-206, (3)] are cytotoxic agents that induce double-strand breaks (DSBs) in DNA. Here we elucidate the cellular responses to these agents and identify synthetic lethal interactions with specific DNA repair factors. Toward this end, we first characterized the kinetics of DNA damage by 1 and 3 in human chronic myelogenous leukemia (K562) cells. DSBs are rapidly induced by 3, reaching a maximum at 15 min post addition and are resolved within 4 h. By comparison, DSB production by 1 requires 2-4 h to achieve maximal values and >8 h to achieve resolution. As evidenced by an alkaline comet unwinding assay, 3 induces extensive DNA damage, suggesting that the observed DSBs arise from closely spaced single-strand breaks (SSBs). Both 1 and 3 induce ataxia telangiectasia mutated- (ATM-) and DNA-dependent protein kinase- (DNA-PK-) dependent production of phospho-SER139-histone H2AX (γH2AX) and generation of p53 binding protein 1 (53BP1) foci in K562 cells within 1 h of exposure, which is indicative of activation of nonhomologous end joining (NHEJ) and homologous recombination (HR) repair. Both compounds also lead to ataxia telangiectasia and Rad3-related- (ATR-) dependent production of γH2AX at later time points (6 h post addition), which is indicative of replication stress. 3 is also shown to induce apoptosis. In accord with these data, 1 and 3 were found to be synthetic lethal with certain mutations in DNA DSB repair. 1 potently inhibits the growth of breast cancer type 2, early onset- (BRCA2-) deficient V79 Chinese hamster lung fibroblast cell line derivative (VC8), and phosphatase and tensin homologue deleted on chromosome ten- (PTEN-) deficient human glioblastoma (U251) cell lines, with LC50 values of 1.5 ± 0.5 and 2.0 ± 0.6 pM, respectively, and selectivities of >11.6 versus the isogenic cell lines transfected with and expressing functional BRCA2 and PTEN genes. 3 inhibits the growth of the same

  12. Responses to the advanced notice of proposed rulemaking EPA published on June 6, 1996 regarding changes to the EPA allowance auctions and elimination of the direct sale

    SciTech Connect

    Critchfield, L.R.

    1997-12-31

    On June 6, 1996, EPA`s Acid Rain Program published an advance notice of proposed rulemaking (ANPRM) in the Federal Register seeking comment on: (1) whether to change the design of the annual sulfur dioxide (SO{sub 2}) allowance auctions; (2) whether to change the timing of the allowance auctions; (3) whether to change the requirement that the minimum price of offered allowances must be in whole dollars, and (4) whether EPA should propose the ability to submit allowance transfers electronically. EPA also published on that day a proposed and direct final rule on whether to eliminate the direct sale. This paper documents the issues addressed in the ANPRM, the comments EPA received, and EPA`s responses to those comments. EPA received comments from 14 separate commenters.

  13. Double ionization of atomic cadmium

    SciTech Connect

    Linusson, P.; Fritzsche, S.; Eland, J. H. D.; Hedin, L.; Karlsson, L.; Feifel, R.

    2011-02-15

    We have recorded the double photoionization spectrum of atomic Cd at four different photon energies in the range 40-200 eV. The main channel is single ionization and subsequent decay of excited Cd{sup +} states, some involving Coster-Kronig processes, whereas direct double ionization is found to be weak. The decay of the excited Cd{sup +} states shows a strong selectivity, related to the configuration of the final state. Double ionization leading to the Cd{sup 2+} ground state is investigated in some detail and is found to proceed mainly through ionization and decay of 4d correlation satellites. The most prominent autoionization peaks have been identified with the aid of quantum-mechanical calculations.

  14. Distinct mechanisms for opposite functions of homeoproteins Cdx2 and HoxB7 in double-strand break DNA repair in colon cancer cells.

    PubMed

    Soret, Christine; Martin, Elisabeth; Duluc, Isabelle; Dantzer, Françoise; Vanier, Marie; Gross, Isabelle; Freund, Jean-Noël; Domon-Dell, Claire

    2016-05-01

    Homeobox genes, involved in embryonic development and tissues homeostasis in adults, are often deregulated in cancer, but their relevance in pathology is far from being fully elucidated. In colon cancers, we report that the homeoproteins HoxB7 and Cdx2 exhibit different heterogeneous patterns, Cdx2 being localized in moderately altered neoplasic glands in contrast to HoxB7 which predominates in poorly-differentiated areas; they are coexpressed in few cancer cells. In human colon cancer cells, both homeoproteins interact with the DNA repair factor KU70/80, but functional studies reveal opposite effects: HoxB7 stimulates DNA repair and cell survival upon etoposide treatment, whereas Cdx2 inhibits both processes. The stimulatory effect of HoxB7 on DNA repair requires the transactivation domain linked to the homeodomain involved in the interaction with KU70/80, whereas the transactivation domain of Cdx2 is dispensable for its inhibitory function, which instead needs the homeodomain to interact with KU70/80 and the C-terminal domain. Thus, HoxB7 and Cdx2 respectively use transcription-dependent and -independent mechanisms to stimulate and inhibit DNA repair. In addition, in cells co-expressing both homeoproteins, Cdx2 lessens DNA repair activity through a novel mechanism of inhibition of the transcriptional function of HoxB7, whereby Cdx2 forms a molecular complex with HoxB7 and prevents it to recognize its target in the chromatin. These results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 and Cdx2 in colon cancer cells, making the balance between these factors a determinant and a potential indicator of the efficacy of genotoxic drugs. PMID:26902420

  15. Estimating the impact of various menu labeling formats on parents' demand for fast-food kids' meals for their children: An experimental auction.

    PubMed

    Hobin, Erin; Lillico, Heather; Zuo, Fei; Sacco, Jocelyn; Rosella, Laura; Hammond, David

    2016-10-01

    This study experimentally tested whether parents' demand for fast-food kids' meals for their children is influenced by various menu labeling formats disclosing calorie and sodium information. The study also examined the effect of various menu labeling formats on parents' ability to identify fast-food kids' meals with higher calorie and sodium content. Online surveys were conducted among parents of children aged 3-12. Parents were randomized to view 1 of 5 menu conditions: 1) No Nutrition Information; 2) Calories-Only; 3) Calories + Contextual Statement (CS); 4) Calories, Sodium, + CS; and, 5) Calorie and Sodium in Traffic Lights + CS. Using an established experimental auction study design, parents viewed replicated McDonald's menus according to their assigned condition and were asked to bid on 4 Happy Meals. A randomly selected price was chosen; bids equal to or above this price "won" the auction, and bids less than this price "lost" the auction. After the auction, participants were asked to identify the Happy Meal with the highest calories and sodium content. Adjusting for multiple comparisons and covariates, the Calories, Sodium, + CS menu had a mean attributed value across all 4 Happy Meals which was 8% lower (-$0.31) than the Calories + CS menu (p < 0.05). Significantly more parents in the 4 menu conditions providing calories were able to correctly identify the Happy Meal with the highest calories (p < 0.0001) and significantly more parents in the 2 conditions providing sodium information were able to correctly identify the Happy Meal with the highest sodium content (p < 0.0001). Menus disclosing both calories and sodium information may reduce demand for fast-food kids' meals and better support parents in making more informed and healthier food choices for their children. PMID:27317971

  16. Examining the relationship between psychosocial and behavioral proxies for future consumption behavior: self-reported impact and bidding behavior in an experimental auction study on cigarette labeling

    PubMed Central

    Rousu, Matthew C.; Thrasher, James F.

    2014-01-01

    Experimental and observational research often involves asking consumers to self-report the impact of some proposed option. Because self-reported responses involve no consequence to the respondent for falsely revealing how he or she feels about an issue, self-reports may be subject to social desirability and other influences that bias responses in important ways. In this article, we analyzed data from an experiment on the impact of cigarette packaging and pack warnings, comparing smokers’ self-reported impact (four-item scale) and the bids they placed in experimental auctions to estimate differences in demand. The results were consistent across methods; however, the estimated effect size associated with different warning labels was two times greater for the four-item self-reported response scale when compared to the change in demand as indicated by auction bids. Our study provides evidence that self-reported psychosocial responses provide a valid proxy for behavioral change as reflected by experimental auction bidding behavior. More research is needed to better understand the advantages and disadvantages of behavioral economic methods and traditional self-report approaches to evaluating health behavior change interventions. PMID:24399267

  17. A double-double/double-single computation package

    SciTech Connect

    Bailey, David H.

    2004-12-01

    The DDFUNIDSFUN software permits a new or existing Fortran-90 program to utilize double-double precision (approx. 31 digits) or double-single precision (approx. 14 digits) arithmetic. Double-double precision is required by a rapidly expandirtg body of scientific computations in physics and mathematics, for which the conventional 64-bit IEEE computer arithmetic (about 16 decimal digit accuracy) is not sufficient. Double-single precision permits users of systems that do not have hardware 64-bit IEEE arithmetic (such as some game systems) to perform arithmetic at a precision nearly as high as that of systems that do. Both packages run significantly faster Than using multiple precision or arbitrary precision software for this purpose. The package includes an extensive set of low-level routines to perform high-precision arithmetic, including routines to calculate various algebraic and transcendental functions, such as square roots, sin, ccc, exp, log and others. In addition, the package includes high-level translation facilities, so that Fortran programs can utilize these facilities by making only a few changes to conventional Fortran programs. In most cases, the only changes that are required are to change the type statements of variables that one wishes to be treated as multiple precision, plus a few other minor changes. The DDFUN package is similar in functionality to the double-double part of the GD package, which was previously written at LBNL. However, the DDFUN package is written exclusively in Fortran-90, thus avoidIng difficulties that some users experience when using GD, which includes both Fortran-90 and C++ code.

  18. A double-double/double-single computation package

    Energy Science and Technology Software Center (ESTSC)

    2004-12-01

    The DDFUNIDSFUN software permits a new or existing Fortran-90 program to utilize double-double precision (approx. 31 digits) or double-single precision (approx. 14 digits) arithmetic. Double-double precision is required by a rapidly expandirtg body of scientific computations in physics and mathematics, for which the conventional 64-bit IEEE computer arithmetic (about 16 decimal digit accuracy) is not sufficient. Double-single precision permits users of systems that do not have hardware 64-bit IEEE arithmetic (such as some game systems)more » to perform arithmetic at a precision nearly as high as that of systems that do. Both packages run significantly faster Than using multiple precision or arbitrary precision software for this purpose. The package includes an extensive set of low-level routines to perform high-precision arithmetic, including routines to calculate various algebraic and transcendental functions, such as square roots, sin, ccc, exp, log and others. In addition, the package includes high-level translation facilities, so that Fortran programs can utilize these facilities by making only a few changes to conventional Fortran programs. In most cases, the only changes that are required are to change the type statements of variables that one wishes to be treated as multiple precision, plus a few other minor changes. The DDFUN package is similar in functionality to the double-double part of the GD package, which was previously written at LBNL. However, the DDFUN package is written exclusively in Fortran-90, thus avoidIng difficulties that some users experience when using GD, which includes both Fortran-90 and C++ code.« less

  19. The Cambridge Double Star Atlas

    NASA Astrophysics Data System (ADS)

    MacEvoy, Bruce; Tirion, Wil

    2015-12-01

    Preface; What are double stars?; The binary orbit; Double star dynamics; Stellar mass and the binary life cycle; The double star population; Detecting double stars; Double star catalogs; Telescope optics; Preparing to observe; Helpful accessories; Viewing challenges; Next steps; Appendices: target list; Useful formulas; Double star orbits; Double star catalogs; The Greek alphabet.

  20. Double outlet right ventricle

    MedlinePlus

    ... medlineplus.gov/ency/article/007328.htm Double outlet right ventricle To use the sharing features on this page, please enable JavaScript. Double outlet right ventricle (DORV) is a heart disease that is ...

  1. Chromosome doubling method

    DOEpatents

    Kato, Akio

    2006-11-14

    The invention provides methods for chromosome doubling in plants. The technique overcomes the low yields of doubled progeny associated with the use of prior techniques for doubling chromosomes in plants such as grasses. The technique can be used in large scale applications and has been demonstrated to be highly effective in maize. Following treatment in accordance with the invention, plants remain amenable to self fertilization, thereby allowing the efficient isolation of doubled progeny plants.

  2. Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion effects on the cleavage rates of 5′-oxy and 5′-thio substrates by a hammerhead ribozyme

    PubMed Central

    Zhou, De-Min; Zhang, Li-He; Taira, Kazunari

    1997-01-01

    In a previous examination using natural all-RNA substrates that contained either a 5′-oxy or 5′-thio leaving group at the cleavage site, we demonstrated that (i) the attack by the 2′-oxygen at C17 on the phosphorus atom is the rate-limiting step only for the substrate that contains a 5′-thio group (R11S) and (ii) the departure of the 5′ leaving group is the rate-limiting step for the natural all-RNA substrate (R11O) in both nonenzymatic and hammerhead ribozyme-catalyzed reactions; the energy diagrams for these reactions were provided in our previous publication. In this report we found that the rate of cleavage of R11O by a hammerhead ribozyme was enhanced 14-fold when Mg2+ ions were replaced by Mn2+ ions, whereas the rate of cleavage of R11S was enhanced only 2.2-fold when Mg2+ ions were replaced by Mn2+ ions. This result appears to be exactly the opposite of that predicted from the direct coordination of the metal ion with the leaving 5′-oxygen, because a switch in metal ion specificity was not observed with the 5′-thio substrate. However, our quantitative analyses based on the previously provided energy diagram indicate that this result is in accord with the double-metal-ion mechanism of catalysis. PMID:9405614

  3. Cardiovascular risk and mortality in end-stage renal disease patients undergoing dialysis: sleep study, pulmonary function, respiratory mechanics, upper airway collapsibility, autonomic nervous activity, depression, anxiety, stress and quality of life: a prospective, double blind, randomized controlled clinical trial

    PubMed Central

    2013-01-01

    Background Chronic kidney disease (CKD) is one of the most serious public health problems. The increasing prevalence of CKD in developed and developing countries has led to a global epidemic. The hypothesis proposed is that patients undergoing dialysis would experience a marked negative influence on physiological variables of sleep and autonomic nervous system activity, compromising quality of life. Methods/Design A prospective, consecutive, double blind, randomized controlled clinical trial is proposed to address the effect of dialysis on sleep, pulmonary function, respiratory mechanics, upper airway collapsibility, autonomic nervous activity, depression, anxiety, stress and quality of life in patients with CKD. The measurement protocol will include body weight (kg); height (cm); body mass index calculated as weight/height2; circumferences (cm) of the neck, waist, and hip; heart and respiratory rates; blood pressures; Mallampati index; tonsil index; heart rate variability; maximum ventilatory pressures; negative expiratory pressure test, and polysomnography (sleep study), as well as the administration of specific questionnaires addressing sleep apnea, excessive daytime sleepiness, depression, anxiety, stress, and quality of life. Discussion CKD is a major public health problem worldwide, and its incidence has increased in part by the increased life expectancy and increasing number of cases of diabetes mellitus and hypertension. Sleep disorders are common in patients with renal insufficiency. Our hypothesis is that the weather weight gain due to volume overload observed during interdialytic period will influence the degree of collapsibility of the upper airway due to narrowing and predispose to upper airway occlusion during sleep, and to investigate the negative influences of haemodialysis in the physiological variables of sleep, and autonomic nervous system, and respiratory mechanics and thereby compromise the quality of life of patients. Trial registration The

  4. 47 CFR 1.2104 - Competitive bidding mechanisms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... on bidders who withdraw high bids during the course of an auction, or who default on payments due... that withdraws a bid during the course of an auction is subject to a withdrawal payment equal to...

  5. Origin of double-line structure in nonsequential double ionization by few-cycle laser pulses

    NASA Astrophysics Data System (ADS)

    Huang, Cheng; Zhong, Mingmin; Wu, Zhengmao

    2016-07-01

    We investigate nonsequential double ionization (NSDI) of molecules by few-cycle laser pulses at the laser intensity of 1.2-1.5 × 1014 W/cm2 using the classical ensemble model. The same double-line structure as the lower intensity (1.0 × 1014 W/cm2) is also observed in the correlated electron momentum spectra for 1.2-1.4 × 1014 W/cm2. However, in contrast to the lower intensity where NSDI proceeds only through the recollision-induced double excitation with subsequent ionization (RDESI) mechanism, here, the recollision-induced excitation with subsequent ionization (RESI) mechanism has a more significant contribution to NSDI. This indicates that RDESI is not necessary for the formation of the double-line structure and RESI can give rise to the same type of structure independently. Furthermore, we explore the ultrafast dynamics underlying the formation of the double-line structure in RESI.

  6. Encouraging stormwater management using a reverse auction: potential to restore stream ecosystems

    EPA Science Inventory

    Stormwater runoff is the primary mechanism by which urbanizing landscapes disrupt natural, stream ecosystems. Source control management has been demonstrated as an effective and cost-efficient method for reducing stormwater runoff; however, sufficiently widespread implementation...

  7. Negative Coulomb Drag in Double Bilayer Graphene.

    PubMed

    Li, J I A; Taniguchi, T; Watanabe, K; Hone, J; Levchenko, A; Dean, C R

    2016-07-22

    We report on an experimental measurement of Coulomb drag in a double quantum well structure consisting of bilayer-bilayer graphene, separated by few layer hexagonal boron nitride. At low temperatures and intermediate densities, a novel negative drag response with an inverse sign is observed, distinct from the momentum and energy drag mechanisms previously reported in double monolayer graphene. By varying the device aspect ratio, the negative drag component is suppressed and a response consistent with pure momentum drag is recovered. In the momentum drag dominated regime, excellent quantitative agreement with the density and temperature dependence predicted for double bilayer graphene is found. PMID:27494491

  8. Electric fields and double layers in plasmas

    NASA Technical Reports Server (NTRS)

    Singh, Nagendra; Thiemann, H.; Schunk, R. W.

    1987-01-01

    Various mechanisms for driving double layers in plasmas are briefly described, including applied potential drops, currents, contact potentials, and plasma expansions. Some dynamical features of the double layers are discussed. These features, as seen in simulations, laboratory experiments, and theory, indicate that double layers and the currents through them undergo slow oscillations which are determined by the ion transit time across an effective length of the system in which double layers form. It is shown that a localized potential dip forms at the low potential end of a double layer, which interrupts the electron current through it according to the Langmuir criterion, whenever the ion flux into the double is disrupted. The generation of electric fields perpendicular to the ambient magnetic field by contact potentials is also discussed. Two different situations were considered; in one, a low-density hot plasma is sandwiched between high-density cold plasmas, while in the other a high-density current sheet permeates a low-density background plasma. Perpendicular electric fields develop near the contact surfaces. In the case of the current sheet, the creation of parallel electric fields and the formation of double layers are also discussed when the current sheet thickness is varied. Finally, the generation of electric fields and double layers in an expanding plasma is discussed.

  9. Ionizing radiation and genetic risks. XVII. Formation mechanisms underlying naturally occurring DNA deletions in the human genome and their potential relevance for bridging the gap between induced DNA double-strand breaks and deletions in irradiated germ cells.

    PubMed

    Sankaranarayanan, Krishnaswami; Taleei, Reza; Rahmanian, Shirin; Nikjoo, Hooshang

    2013-01-01

    While much is known about radiation-induced DNA double-strand breaks (DSBs) and their repair, the question of how deletions of different sizes arise as a result of the processing of DSBs by the cell's repair systems has not been fully answered. In order to bridge this gap between DSBs and deletions, we critically reviewed published data on mechanisms pertaining to: (a) repair of DNA DSBs (from basic studies in this area); (b) formation of naturally occurring structural variation (SV) - especially of deletions - in the human genome (from genomic studies) and (c) radiation-induced mutations and structural chromosomal aberrations in mammalian somatic cells (from radiation mutagenesis and radiation cytogenetic studies). The specific aim was to assess the relative importance of the postulated mechanisms in generating deletions in the human genome and examine whether empirical data on radiation-induced deletions in mouse germ cells are consistent with predictions of these mechanisms. The mechanisms include (a) NHEJ, a DSB repair process that does not require any homology and which functions in all stages of the cell cycle (and is of particular relevance in G0/G1); (b) MMEJ, also a DSB repair process but which requires microhomology and which presumably functions in all cell cycle stages; (c) NAHR, a recombination-based DSB repair mechanism which operates in prophase I of meiosis in germ cells; (d) MMBIR, a microhomology-mediated, replication-based mechanism which operates in the S phase of the cell cycle, and (e) strand slippage during replication (involved in the origin of small insertions and deletions (INDELs). Our analysis permits the inference that, between them, these five mechanisms can explain nearly all naturally occurring deletions of different sizes identified in the human genome, NAHR and MMBIR being potentially more versatile in this regard. With respect to radiation-induced deletions, the basic studies suggest that those arising as a result of the operation

  10. Observing Double Stars

    NASA Astrophysics Data System (ADS)

    Genet, Russell M.; Fulton, B. J.; Bianco, Federica B.; Martinez, John; Baxter, John; Brewer, Mark; Carro, Joseph; Collins, Sarah; Estrada, Chris; Johnson, Jolyon; Salam, Akash; Wallen, Vera; Warren, Naomi; Smith, Thomas C.; Armstrong, James D.; McGaughey, Steve; Pye, John; Mohanan, Kakkala; Church, Rebecca

    2012-05-01

    Double stars have been systematically observed since William Herschel initiated his program in 1779. In 1803 he reported that, to his surprise, many of the systems he had been observing for a quarter century were gravitationally bound binary stars. In 1830 the first binary orbital solution was obtained, leading eventually to the determination of stellar masses. Double star observations have been a prolific field, with observations and discoveries - often made by students and amateurs - routinely published in a number of specialized journals such as the Journal of Double Star Observations. All published double star observations from Herschel's to the present have been incorporated in the Washington Double Star Catalog. In addition to reviewing the history of visual double stars, we discuss four observational technologies and illustrate these with our own observational results from both California and Hawaii on telescopes ranging from small SCTs to the 2-meter Faulkes Telescope North on Haleakala. Two of these technologies are visual observations aimed primarily at published "hands-on" student science education, and CCD observations of both bright and very faint doubles. The other two are recent technologies that have launched a double star renaissance. These are lucky imaging and speckle interferometry, both of which can use electron-multiplying CCD cameras to allow short (30 ms or less) exposures that are read out at high speed with very low noise. Analysis of thousands of high speed exposures allows normal seeing limitations to be overcome so very close doubles can be accurately measured.

  11. 47 CFR 90.903 - Competitive bidding mechanisms.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Bureau will establish and may vary the sequence in which 800 MHz SMR licenses for Spectrum Blocks A through V will be auctioned. (b) Grouping. (1) All EA licenses for Spectrum Blocks A through V will be... the auction, an alternative method of grouping these licenses for auction. (2) Spectrum blocks...

  12. 47 CFR 90.903 - Competitive bidding mechanisms.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Bureau will establish and may vary the sequence in which 800 MHz SMR licenses for Spectrum Blocks A through V will be auctioned. (b) Grouping. (1) All EA licenses for Spectrum Blocks A through V will be... the auction, an alternative method of grouping these licenses for auction. (2) Spectrum blocks...

  13. 47 CFR 90.903 - Competitive bidding mechanisms.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Bureau will establish and may vary the sequence in which 800 MHz SMR licenses for Spectrum Blocks A through V will be auctioned. (b) Grouping. (1) All EA licenses for Spectrum Blocks A through V will be... the auction, an alternative method of grouping these licenses for auction. (2) Spectrum blocks...

  14. 47 CFR 90.903 - Competitive bidding mechanisms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Bureau will establish and may vary the sequence in which 800 MHz SMR licenses for Spectrum Blocks A through V will be auctioned. (b) Grouping. (1) All EA licenses for Spectrum Blocks A through V will be... the auction, an alternative method of grouping these licenses for auction. (2) Spectrum blocks...

  15. 47 CFR 90.903 - Competitive bidding mechanisms.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Bureau will establish and may vary the sequence in which 800 MHz SMR licenses for Spectrum Blocks A through V will be auctioned. (b) Grouping. (1) All EA licenses for Spectrum Blocks A through V will be... the auction, an alternative method of grouping these licenses for auction. (2) Spectrum blocks...

  16. Topological Quantum Double

    NASA Astrophysics Data System (ADS)

    Bonneau, Philippe

    Following a preceding paper showing how the introduction of a t.v.s. topology on quantum groups led to a remarkable unification and rigidification of the different definitions, we adapt here, in the same way, the definition of quantum double. This topological double is dualizable and reflexive (even for infinite dimensional algebras). In a simple case we show, considering the double as the "zero class" of an extension theory, the uniqueness of the double structure as a quasi-Hopf algebra. A la suite d'un précédent article montrant comment l'introduction d'une topologie d'e.v.t. sur les groupes quantiques permet une unification et une rigidification remarquables des différentes définitions, on adapte ici de la même manière la définition du double quantique. Ce double topologique est alors dualisable et reflexif (même pour des algèbres de dimension infinie). Dans un cas simple on montre, en considérant le double comme la "classe zéro" d'une théorie d'extensions, l'unicité de cette structure comme algèbre quasi-Hopf.

  17. On fair, effective and efficient REDD mechanism design

    PubMed Central

    2009-01-01

    The issues surrounding 'Reduced Emissions from Deforestation and Forest Degradation' (REDD) have become a major component of continuing negotiations under the United Nations Framework Convention on Climate Change (UNFCCC). This paper aims to address two key requirements of any potential REDD mechanism: first, the generation of measurable, reportable and verifiable (MRV) REDD credits; and secondly, the sustainable and efficient provision of emission reductions under a robust financing regime. To ensure the supply of MRV credits, we advocate the establishment of an 'International Emission Reference Scenario Coordination Centre' (IERSCC). The IERSCC would act as a global clearing house for harmonized data to be used in implementing reference level methodologies. It would be tasked with the collection, reporting and subsequent processing of earth observation, deforestation- and degradation driver information in a globally consistent manner. The IERSCC would also assist, coordinate and supervise the computation of national reference scenarios according to rules negotiated under the UNFCCC. To overcome the threats of "market flooding" on the one hand and insufficient economic incentives for REDD on the other hand, we suggest an 'International Investment Reserve' (IIR) as REDD financing framework. In order to distribute the resources of the IIR we propose adopting an auctioning mechanism. Auctioning not only reveals the true emission reduction costs, but might also allow for incentivizing the protection of biodiversity and socio-economic values. The introduced concepts will be vital to ensure robustness, environmental integrity and economic efficiency of the future REDD mechanism. PMID:19943927

  18. Double Degenerate Binary Systems

    SciTech Connect

    Yakut, K.

    2011-09-21

    In this study, angular momentum loss via gravitational radiation in double degenerate binary (DDB)systems (NS + NS, NS + WD, WD + WD, and AM CVn) is studied. Energy loss by gravitational waves has been estimated for each type of systems.

  19. Double aortic arch

    MedlinePlus

    ... double aortic arch may press on the windpipe (trachea) and esophagus, leading to trouble breathing and swallowing. ... to relieve pressure on the esophagus and windpipe (trachea). The surgeon ties off the smaller branch and ...

  20. Differential double capture cross sections in p+He collisions

    SciTech Connect

    Schulz, M.; Brand, J. A.; Vajnai, T.

    2007-02-15

    We have measured differential double capture cross sections for 15 to 150 keV p+He collisions. We also analyzed differential double to single capture ratios, where we find pronounced peak structures. An explanation of these structures probably requires a quantum-mechanical description of elastic scattering between the projectile and the target nucleus. Strong final-state correlations have a large effect on the magnitude of the double capture cross sections.

  1. Piezotronically modified double Schottky barriers in ZnO varistors.

    PubMed

    Raidl, Nadine; Supancic, Peter; Danzer, Robert; Hofstätter, Michael

    2015-03-25

    Double Schottky barriers in ZnO are modified piezotronically by the application of mechanical stresses. New effects such as the enhancement of the potential barrier height and the increase or decrease of the natural barrier asymmetry are presented. Also, an extended model for the piezotronic modification of double Schottky barriers is given. PMID:25655302

  2. Dynamics of Double Stochastic Operators

    NASA Astrophysics Data System (ADS)

    Saburov, Mansoor

    2016-03-01

    A double stochastic operator is a generalization of a double stochastic matrix. In this paper, we study the dynamics of double stochastic operators. We give a criterion for a regularity of a double stochastic operator in terms of absences of its periodic points. We provide some examples to insure that, in general, a trajectory of a double stochastic operator may converge to any interior point of the simplex.

  3. Double Emulsion Templated Celloidosomes

    NASA Astrophysics Data System (ADS)

    Arriaga, Laura R.; Marquez, Samantha M.; Kim, Shin-Hyun; Chang, Connie; Wilking, Jim; Monroy, Francisco; Marquez, Manuel; Weitz, David A.

    2012-02-01

    We present a novel approach for fabricating celloidosomes, which represent a hollow and spherical three-dimensional self-assembly of living cells encapsulating an aqueous core. Glass- capillary microfluidics is used to generate monodisperse water-in-oil-in-water double emulsion templates using lipids as stabilizers. Such templates allow for obtaining single but also double concentric celloidosomes. In addition, after a solvent removal step the double emulsion templates turn into monodisperse lipid vesicles, whose membrane spontaneously phase separates when choosing the adequate lipid composition, providing the adequate scaffold for fabricating Janus-celloidosomes. These structures may find applications in the development of bioreactors in which the synergistic effects of two different types of cells selectively adsorbed on one of the vesicle hemispheres may be exploited.

  4. Tracking The Double Eagle

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Last summer a trio of aeronauts made aviation history. Ben Abruzzo, Maxie Anderson and Larry Newman, all of Albuquerque, New Mexico, piloted their balloon Double Eagle I1 from Presque Isle, Maine to Miserey, France, some 50 miles from Paris. They were the first to negotiate a successful Atlantic crossing in a freeflying balloon after a score of attempts over a span of more than a century. A year earlier, Abruzzo and Anderson had made an unsuccessful try in their predecessor balloon Double Eagle. On that occasion, a NASA-developed satellite beacon helped save their lives. Carried aboard the balloon, the simple, seven-pound beacon continuously transmitted signals to NASA's Nimbus-6 satellite. Nimbus relayed the signals to monitors at Goddard Space Flight Center, enabling Goddard to compute the balloon's position. Position reports were then telephoned regularly to Double Eagle's control center at Bedford, Massachusetts. This monitoring system proved invaluable when the balloon encountered trouble several days after liftoff.

  5. Double face sealing device

    NASA Technical Reports Server (NTRS)

    Weddendorf, Bruce C. (Inventor)

    1991-01-01

    A double face sealing device for mounting between two surfaces to provide an airtight and fluid-tight seal between a closure member bearing one of the surfaces and a structure or housing bearing the other surface which extends around the opening or hatchway to be closed. The double face sealing device includes a plurality of sections or segments mounted to one of the surfaces, each having a main body portion, a pair of outwardly extending and diverging, cantilever, spring arms, and a pair of inwardly extending and diverging, cantilever, spring arms, an elastomeric cover on the distal, free, ends of the outwardly extending and diverging spring arms, and an elastomeric cover on the distal, free, ends of the inwardly extending and diverging spring arms. The double face sealing device has application or use in all environments requiring a seal, but is particularly useful to seal openings or hatchways between compartments of spacecraft or aircraft.

  6. Mechanical Paradox: The Uphill Roller

    ERIC Educational Resources Information Center

    Cortes, Emilio; Cortes-Poza, D.

    2011-01-01

    We analyse in detail the dynamics of a mechanical system which is a rigid body with the geometry of a double cone. This double cone is apparently able to spontaneously roll uphill along inclined rails. The experiment has been known for some centuries, and because of its peculiar behaviour, it has been named "mechanical paradox". Although this…

  7. Design friendly double patterning

    NASA Astrophysics Data System (ADS)

    Yesilada, Emek

    2012-03-01

    Double patterning using 193nm immersion has been adapted as the solution to enable 2x nm technology nodes until the arrival of EUV tools. As a result the past few years have seen a huge effort in creating double patterning friendly design flows. These flows have so far proposed a combination of decomposition rules at cell level and/or at placement level as well as sophisticated decomposition tools with varying density, design iteration and decomposition complexity penalties. What is more, designers have to familiarize themselves with double patterning challenges and decomposition tools. In this paper an alternative approach is presented that allows the development of dense standard cells with minimal impact on design flow due to double patterning. A real case study is done on 20nm node first metal layer where standard cells are designed without considering decomposition restrictions. The resulting layout is carefully studied in order to establish decomposition or color rules that can map the layout into two masks required for double patterning but without the need of complex coloring algorithms. Since the rules are derived from a decomposition unaware design they do not in return impose heavy restrictions on the design at the cell or placement level and show substantial density gains compared to previously proposed methods. Other key advantages are a simplified design flow without complex decomposition tools that can generate a faster time to market solution all at the same time keeping designers isolated from the challenges of the double patterning. The derived design rules highlight process development path required for design driven manufacturing.

  8. Double Bragg Interferometry.

    PubMed

    Ahlers, H; Müntinga, H; Wenzlawski, A; Krutzik, M; Tackmann, G; Abend, S; Gaaloul, N; Giese, E; Roura, A; Kuhl, R; Lämmerzahl, C; Peters, A; Windpassinger, P; Sengstock, K; Schleich, W P; Ertmer, W; Rasel, E M

    2016-04-29

    We employ light-induced double Bragg diffraction of delta-kick collimated Bose-Einstein condensates to create three symmetric Mach-Zehnder interferometers. They rely on (i) first-order, (ii) two successive first-order, and (iii) second-order processes which demonstrate the scalability of the corresponding momentum transfer. With respect to devices based on conventional Bragg scattering, these symmetric interferometers double the scale factor and feature a better suppression of noise and systematic uncertainties intrinsic to the diffraction process. Moreover, we utilize these interferometers as tiltmeters for monitoring their inclination with respect to gravity. PMID:27176520

  9. Double Bragg Interferometry

    NASA Astrophysics Data System (ADS)

    Ahlers, H.; Müntinga, H.; Wenzlawski, A.; Krutzik, M.; Tackmann, G.; Abend, S.; Gaaloul, N.; Giese, E.; Roura, A.; Kuhl, R.; Lämmerzahl, C.; Peters, A.; Windpassinger, P.; Sengstock, K.; Schleich, W. P.; Ertmer, W.; Rasel, E. M.

    2016-04-01

    We employ light-induced double Bragg diffraction of delta-kick collimated Bose-Einstein condensates to create three symmetric Mach-Zehnder interferometers. They rely on (i) first-order, (ii) two successive first-order, and (iii) second-order processes which demonstrate the scalability of the corresponding momentum transfer. With respect to devices based on conventional Bragg scattering, these symmetric interferometers double the scale factor and feature a better suppression of noise and systematic uncertainties intrinsic to the diffraction process. Moreover, we utilize these interferometers as tiltmeters for monitoring their inclination with respect to gravity.

  10. Double-helix stellarator

    SciTech Connect

    Moroz, P.E.

    1997-09-01

    A new stellarator configuration, the Double-Helix Stellarator (DHS), is introduced. This novel configuration features a double-helix center post as the only helical element of the stellarator coil system. The DHS configuration has many unique characteristics. One of them is the extreme low plasma aspect ratio, A {approx} 1--1.2. Other advantages include a high enclosed volume, appreciable rotational transform, and a possibility of extreme-high-{beta} MHD equilibria. Moreover, the DHS features improved transport characteristics caused by the absence of the magnetic field ripple on the outboard of the torus. Compactness, simplicity and modularity of the coil system add to the DHS advantages for fusion applications.

  11. Double arch mirror study

    NASA Technical Reports Server (NTRS)

    Vukobratovich, D.; Hillman, D.

    1983-01-01

    The development of a method of mounting light weight glass mirrors for astronomical telescopes compatible with the goals of the Shuttle Infrared Telescope Facility (SIRTF) was investigated. A 20 in. diameter double arch lightweight mirror previously fabricated was modified to use a new mount configuration. This mount concept was developed and fabricated. The mounting concept of the double mounting mirror is outlined. The modifications made to the mirror, fabrication of the mirror mount, and room temperature testing of the mirror and mount and the extension of the mirror and mount concept to a full size (40 in. diameter) primary mirror for SIRTF are discussed.

  12. Experimental evidence of the double-porosity effects in geomaterials

    NASA Astrophysics Data System (ADS)

    Tran Ngoc, Tien; Lewandowska, Jolanta; Bertin, Henri

    2014-06-01

    Double-porosity is an important characteristic of microstructure in a large range of geomaterials. It designs porous media with connected fissures/fractures or aggregated soils. The origin of double-porosity can be natural or/and it can result from mechanical, chemical or biological damage. The presence of double-porosity can significantly affect the behaviour of geomaterials. In this paper we provide an experimental evidence of the double-porosity effects by performing laboratory experiments. Series of tracer dispersion experiments (in saturated and unsaturated steady-state water flow conditions) in a physical model of double-porosity geomaterial were carried out. For the comparative purposes, experiments of the same type were also performed in a singleporosity model medium. The results clearly showed that the double-porosity microstructure leads to the non-Fickian behaviour of the tracer (early breakthrough and long tail) in both saturated and unsaturated cases.

  13. Comparing the 2000 and 2005 factors affecting the selling price of feeder cattle sold at Arkansas livestock auctions.

    PubMed

    Troxel, T R; Barham, B L

    2007-12-01

    The objectives of the study were to determine how factors affecting the selling price of feeder calves changed from 2000 to 2005 and to examine the perception that discounts narrow or even disappear as calf supplies decrease and selling prices increase. Data from weekly Arkansas livestock auctions were collected from January 1 to December 31 in 2000 and 2005. Data included calf sex, breed type, color, muscle score, horn status, frame score, fill, condition, health, and BW. Mean selling prices for 2000 and 2005 were $92.91 +/- 15.05 and $118.32 +/- 15.13 (mean +/- SD; $/45.45 kg), respectively. Individual price observations were subtracted from the respective annual means and became the dependent variable. The selling prices for feeder calves sold in groups of 2 to 5 calves and in groups of >/= 6 calves were greater in 2005 than 2000 (P < 0.001). Steers received a greater premium ($6.48 +/- 0.09 vs. $6.02 +/- 0.08; mean +/- SE) and bull calves received greater discounts ($0.30 +/- 0.14 vs. $1.68 +/- 0.09) in 2005 than in 2000. Breeds types that increased in value from 2000 to 2005 were Angus x Hereford, Angus, Angus x Charolais, and Brahman (P < 0.001). Breed types that received a reduced selling price in 2005 compared with 2000 (P < 0.001) were one-fourth Brahman Cross, Charolais, Charolais x Limousin, Hereford x Limousin, Limousin, Limousin x one-fourth Brahman, Longhorn, Saler and Simmental. Yellow-white face, black-white face, black, and gray feeder calves received an increase in selling price from 2000 to 2005 (P < 0.001). Although fewer horned feeder calves were sold in 2005 (P < 0.01), they received greater discounts in 2005 than 2000 (-$2.86 +/- 0.16 and -$0.51 +/- 0.09; P < 0.001). In 2005, large-framed feeder calves did not receive the premium detected in 2000, but medium-framed feeder calves in 2005 received a greater selling price compared with 2000. Feeder calves with a muscle score of 1 received a greater premium in 2005 compared with 2000 ($2.58 +/- 0

  14. Machine learning bandgaps of double perovskites

    NASA Astrophysics Data System (ADS)

    Pilania, Ghanshyam; Mannodi-Kanakkithodi, Arun; Uberuaga, Blas; Ramprasad, Rampi; Gubernatis, James; Lookman, Turab

    The ability to make rapid and accurate predictions of bandgaps for double perovskites is of much practical interest for a range of applications. While quantum mechanical computations for high-fidelity bandgaps are enormously computation-time intensive and thus impractical in high throughput studies, informatics-based statistical learning approaches can be a promising alternative. Here we demonstrate a systematic feature-engineering approach and a robust learning framework for efficient and accurate predictions of electronic bandgaps for double perovskites. After evaluating a set of nearly 1.2 million features, we identify several elemental features of the constituent atomic species as the most crucial and relevant predictors. The developed models are validated and tested using the best practices of data science (on a dataset of more than 1300 double perovskite bandgaps) and further analyzed to rationalize their prediction performance. Los Alamos National Laboratory LDRD program and the U.S. Department of Energy, Office of Science, Basic Energy Sciences.

  15. Numerical simulations of plasma double layers

    NASA Technical Reports Server (NTRS)

    Goertz, C. K.; Borovsky, J. E.

    1983-01-01

    The results of analytical studies of quasi-static electric fields along geomagnetic field lines are discussed. The calculations were targeted at the structure, generation mechanisms and stability parameters. The field consists of two oppositely charged layers, either weakly or strongly charged, with an electric field between. Existence conditions are defined for the double layer field and balancing requirements are explored. Details of the simulation techniques, i.e., particle in cell and Vlasov simulations, for studying the double layer are outlined, noting that both periodic and quasi-periodic simulations are used. Solutions to Poisson's equation for fixed and floating point boundary conditions are generated. Finally, attention is also given to oblique and two-dimensional magnetic double layers.

  16. Double-Front Detonation Waves

    NASA Astrophysics Data System (ADS)

    Gubin, S. A.; Sumskoi, S. I.; Victorov, S. B.

    According to the theory of detonation, in a detonation wave there is a sound plane, named Chapman-Jouguet (CJ) plane. There are certain stationary parameters for this plane. In this work the possibility of the second CJ plane is shown. This second CJ plane is stationary as well. The physical mechanism of non-equilibrium transition providing the existence of the second CJ plane is presented. There is a non-equilibrium state, when the heat is removed from the reaction zone and the heat capacity decreases sharply. As a result of this non-equilibrium state, the sound velocity increases, and the local supersonic zone with second sonic plane (second CJ plane) appears. So the new mode of detonation wave is predicted. Equations describing this mode of detonation are presented. The exact analytical solution for the second CJ plane parameters is obtained. The example of double-front detonation in high explosive (TNT) is presented. In this double-front structure "nanodiamond-nanographite" phase transition takes place in condensed particles of detonation products.

  17. Double-Glazing Interferometry

    ERIC Educational Resources Information Center

    Toal, Vincent; Mihaylova, Emilia M.

    2009-01-01

    This note describes how white light interference fringes can be seen by observing the Moon through a double-glazed window. White light interferometric fringes are normally observed only in a well-aligned interferometer whose optical path difference is less than the coherence length of the light source, which is approximately one micrometer for…

  18. Rosette (Double Blossom)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Rosette, or double blossom, is a serious disease of erect blackberries that is limited to the genus Rubus. Rosette may occur on trailing blackberries and dewberries, but rarely on red and black raspberries. In the United States, rosette occurs from New Jersey to Illinois and southwest to Texas and i...

  19. Double layers without current

    SciTech Connect

    Perkins, F.W.; Sun, Y.C.

    1980-11-01

    The steady-state solution of the nonlinear Vlasov-Poisson equations is reduced to a nonlinear eigenvalue problem for the case of double-layer (potential drop) boundary conditions. Solutions with no relative electron-ion drifts are found. The kinetic stability is discussed. Suggestions for creating these states in experiments and computer simulations are offered.

  20. Double resonator cantilever accelerometer

    DOEpatents

    Koehler, Dale R.

    1984-01-01

    A digital quartz accelerometer includes a pair of spaced double-ended tuning forks fastened at one end to a base and at the other end through a spacer mass. Transverse movement of the resonator members stresses one and compresses the other, providing a differential frequency output which is indicative of acceleration.