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Sample records for dpi dutch polymer

  1. Applicability of DPI formulations for novel neurokinin receptor antagonist.

    PubMed

    Kumon, M; Yabe, Y; Kasuya, Y; Suzuki, M; Kusai, A; Yonemochi, E; Terada, K

    2008-05-22

    A novel triple neurokinin receptor antagonist (TNRA) could have pharmaceutical efficacy for asthma and/or chronic obstructive pulmonary disease. TNRA is potentially developed as inhalation medicine. The aim of this investigation was to evaluate the applicability of dry powder inhaler (DPI) formulation for TNRA. DPI formulation containing lactose was used for this feasibility study. Mechanofusion process for surface modification was applied on lactose particles to prepare four different DPI formulations. The mixture of TNRA and lactose was administered to rats intratracheally using an insufflator. The deposition pattern and blood concentration profile of TNRA were evaluated. Although there was no significant difference in deposition on deep lungs between the four formulations, DPI formulations containing mechanofusion-processed lactose showed longer T(max) and t(1/2) and higher AUC(0-infinity) and MRT compared to that containing intact lactose. On the other hand, the contact angle measurement showed that the mechanofusion process decreased the polar part of the surface energy of the lactose. Therefore, the prolongation of the wetting of the formulated powder mixture seemed to delay the dissolution of TNRA deposited in respiratory tract. It was concluded that DPI formulation containing mechanofusion-processed lactose could be suitable for inhalation of TNRA. PMID:18294787

  2. Identification and activity of inhibitors of the essential nematode-specific metalloprotease DPY-31.

    PubMed

    France, David J; Stepek, Gillian; Houston, Douglas R; Williams, Lewis; McCormack, Gillian; Walkinshaw, Malcolm D; Page, Antony P

    2015-12-15

    Infection by parasitic nematodes is widespread in the developing world causing extensive morbidity and mortality. Furthermore, infection of animals is a global problem, with a substantial impact on food production. Here we identify small molecule inhibitors of a nematode-specific metalloprotease, DPY-31, using both known metalloprotease inhibitors and virtual screening. This strategy successfully identified several μM inhibitors of DPY-31 from both the human filarial nematode Brugia malayi, and the parasitic gastrointestinal nematode of sheep Teladorsagia circumcincta. Further studies using both free living and parasitic nematodes show that these inhibitors elicit the severe body morphology defect 'Dumpy' (Dpy; shorter and fatter), a predominantly non-viable phenotype consistent with mutants lacking the DPY-31 gene. Taken together, these results represent a start point in developing DPY-31 inhibition as a totally novel mechanism for treating infection by parasitic nematodes in humans and animals. PMID:26546217

  3. Spoken Dutch.

    ERIC Educational Resources Information Center

    Bloomfield, Leonard

    This course in spoken Dutch is intended for use in introductory conversational classes. The book is divided into five major parts, each containing five learning units and one unit devoted to review. Each unit contains sections including (1) basic sentences, (2) word study and review of basic sentences, (3) listening comprehension, and (4)…

  4. Assessment of DPY19L2 Deletion in Familial and Non-Familial Individuals with Globozoospermia and DPY19L2 Genotyping

    PubMed Central

    Modarres, Parastoo; Tanhaei, Somayeh; Tavalaee, Marziyeh; Ghaedi, Kamran; Deemeh, Mohammad Reza; Nasr-Esfahani, Mohammad Hossein

    2016-01-01

    Background Globozoospermia is a rare syndrome with an incidence of less than 0.1% among infertile men. Researchers have recently identified a large deletion, about 200 kbp, encompassing the whole length of DPY19L2 or mutations in SPATA16 and PICK1 genes associated with globozoospermia. The aim of this study was to analyze the DPY19L2 gene deletion using polymerase chain reaction technique for the exons 1, 48, 11 and 22 as well as break point (BP) “a” in globozoospermic men. Materials and Methods In this experimental study, genome samples were collected from 27 men with globozoospermia (cases) and 36 fertile individuals (controls), and genomic analysis was carried out on each sample. Results Deletion of DPY19L2 gene accounted for 74% of individuals with globozoospermia. DPY19L2 gene deletion was considered as the molecular pathogenic factor for the onset of globozoospermia in infertile men. By quantitative real-time polymerase chain reaction (qPCR), we genotyped DPY19L2 deletion and identified carriers within the population. Conclusion This technique may be considered as a method for family counseling and has the potential to be used as a pre-implantation genetic diagnosis, especially in ethnic community with high rate of consanguineous marriages. PMID:27441053

  5. DPY30 regulates pathways in cellular senescence through ID protein expression

    PubMed Central

    Simboeck, Elisabeth; Gutierrez, Arantxa; Cozzuto, Luca; Beringer, Malte; Caizzi, Livia; M Keyes, William; Di Croce, Luciano

    2013-01-01

    Cellular senescence is an intrinsic defense mechanism to various cellular stresses: while still metabolically active, senescent cells stop dividing and enter a proliferation arrest. Here, we identify DPY30, a member of all mammalian histone H3K4 histone methyltransferases (HMTases), as a key regulator of the proliferation potential of human primary cells. Following depletion of DPY30, cells show a severe proliferation defect and display a senescent phenotype, including a flattened and enlarged morphology, elevated level of reactive oxygen species (ROS), increased SA-β-galactosidase activity, and formation of senescence-associated heterochromatin foci (SAHFs). While DPY30 depletion leads to a reduced level of H3K4me3-marked active chromatin, we observed a concomitant activation of CDK inhibitors, including p16INK4a, independent of H3K4me3. ChIP experiments show that key regulators of cell-cycle progression, including ID proteins, are under direct control of DPY30. Because ID proteins are negative regulators of the transcription factors ETS1/2, depletion of DPY30 leads to the transcriptional activation of p16INK4a by ETS1/2 and thus to a senescent-like phenotype. Ectoptic re-introduction of ID protein expression can partially rescue the senescence-like phenotype induced by DPY30 depletion. Thus, our data indicate that DPY30 controls proliferation by regulating ID proteins expression, which in turn lead to senescence bypass. PMID:23872946

  6. Ciprofloxacin DPI: a randomised, placebo-controlled, phase IIb efficacy and safety study on cystic fibrosis

    PubMed Central

    Dorkin, Henry L; Staab, Doris; Operschall, Elisabeth; Alder, Jeff; Criollo, Margarita

    2015-01-01

    Background Treatment of infective bronchitis involving Pseudomonas aeruginosa is a cornerstone of care in patients with cystic fibrosis (CF). This phase IIb, randomised, double-blind, placebo-controlled study assessed the efficacy and safety of ciprofloxacin dry powder for inhalation (DPI) in this population. Methods Patients with CF, ≥12 years of age (N=286), were randomised to ciprofloxacin DPI (32.5 mg (n=93) or 48.75 mg (n=93)), or corresponding placebo (32.5 mg, n=65; 48.75 mg, n=35) twice daily for 28 days. The primary objective was the change in forced expiratory volume in 1 s (FEV1) from baseline (day 0) to end of treatment (day 29) in the intent-to-treat population for ciprofloxacin DPI compared with the corresponding placebo group. Results The primary effectiveness objective was not met; there were no significant differences in change in FEV1 between ciprofloxacin DPI and the corresponding placebo group for either dose (p=0.154). However, in pooled analyses, FEV1 decline from baseline to treatment end was significantly lower with ciprofloxacin DPI than with placebo (pooled data; p=0.02). Ciprofloxacin DPI showed positive effects on sputum bacterial load and quality of life, but these effects were not maintained at the 4-week follow-up. Ciprofloxacin DPI was well tolerated and there were no significant differences in type/incidence of treatment-emergent adverse events by treatment group (p=0.115). Conclusions Further investigations are needed to determine the full scope of the beneficial effects of ciprofloxacin DPI for patients with CF. Trial registration number Clinicaltrials.gov NCT00645788; EudraCT 2008-008314-40. PMID:26688732

  7. DPY19L2 Deletion as a Major Cause of Globozoospermia

    PubMed Central

    Koscinski, Isabelle; ElInati, Elias; Fossard, Camille; Redin, Claire; Muller, Jean; Velez de la Calle, Juan; Schmitt, Françoise; Ben Khelifa, Mariem; Ray, Pierre; Kilani, Zaid; Barratt, Christopher L.R.; Viville, Stéphane

    2011-01-01

    Globozoospermia, characterized by round-headed spermatozoa, is a rare (< 0.1% in male infertile patients) and severe teratozoospermia consisting primarily of spermatozoa lacking an acrosome. Studying a Jordanian consanguineous family in which five brothers were diagnosed with complete globozoospermia, we showed that the four out of five analyzed infertile brothers carried a homozygous deletion of 200 kb on chromosome 12 encompassing only DPY19L2. Very similar deletions were found in three additional unrelated patients, suggesting that DPY19L2 deletion is a major cause of globozoospermia, given that 19% (4 of 21) of the analyzed patients had such deletion. The deletion is most probably due to a nonallelic homologous recombination (NAHR), because the gene is surrounded by two low copy repeats (LCRs). We found DPY19L2 deletion in patients from three different origins and two different breakpoints, strongly suggesting that the deletion results from recurrent events linked to the specific architectural feature of this locus rather than from a founder effect, without fully excluding a recent founder effect. DPY19L2 is associated with a complete form of globozoospermia, as is the case for the first two genes found to be associated with globozoospermia, SPATA16 or PICK1. However, in contrast to SPATA16, for which no pregnancy was reported, pregnancies were achieved, via intracytoplasmic sperm injection, for two patients with DPY19L2 deletion, who then fathered three children. PMID:21397063

  8. Quantitative Analysis of Protein-DNA Interaction by qDPI-ELISA.

    PubMed

    Fischer, Stefan M; Böser, Alexander; Hirsch, Jan P; Wanke, Dierk

    2016-01-01

    The specific binding of DNA-binding proteins to their cognate DNA motifs is a crucial step for gene expression control and chromatin organization in vivo. The development of methods for the identification of in vivo binding regions by, e.g. chromatin immunoprecipitation (ChIP) or DNA adenine methyltransferase identification (Dam-ID) added an additional level of qualitative information for data mining in systems biology or applications in synthetic biology. In this respect, the in vivo techniques outpaced methods for thorough characterization of protein-DNA interaction and, especially, of the binding motifs at single base-pair resolution. The elucidation of DNA-binding capacities of proteins is frequently done with methods such as yeast one-hybrid, electrophoretic mobility shift assay (EMSA) or systematic evolution of ligands by exponential enrichment (SELEX) that provide only qualitative binding information and are not suited for automation or high-throughput screening of several DNA motifs. Here, we describe the quantitative DNA-protein-Interaction-ELISA (qDPI-ELISA) protocol, which makes use of fluorescent fusion proteins and, hence, is faster and easier to handle than the classical DPI-ELISA. Although every DPI-ELISA experiment delivers quantitative information, the qDPI-ELISA has an increased consistency, as it does not depend on immunological detection. We demonstrate the high comparability between probes and different protein extracts in qDPI-ELISA experiments. PMID:27557760

  9. Protein–ligand interactions investigated by thermal shift assays (TSA) and dual polarization interferometry (DPI)

    SciTech Connect

    Grøftehauge, Morten K. Hajizadeh, Nelly R.; Swann, Marcus J.; Pohl, Ehmke

    2015-01-01

    The biophysical characterization of protein–ligand interactions in solution using techniques such as thermal shift assay, or on surfaces using, for example, dual polarization interferometry, plays an increasingly important role in complementing crystal structure determinations. Over the last decades, a wide range of biophysical techniques investigating protein–ligand interactions have become indispensable tools to complement high-resolution crystal structure determinations. Current approaches in solution range from high-throughput-capable methods such as thermal shift assays (TSA) to highly accurate techniques including microscale thermophoresis (MST) and isothermal titration calorimetry (ITC) that can provide a full thermodynamic description of binding events. Surface-based methods such as surface plasmon resonance (SPR) and dual polarization interferometry (DPI) allow real-time measurements and can provide kinetic parameters as well as binding constants. DPI provides additional spatial information about the binding event. Here, an account is presented of new developments and recent applications of TSA and DPI connected to crystallography.

  10. Protein–ligand interactions investigated by thermal shift assays (TSA) and dual polarization interferometry (DPI)

    PubMed Central

    Grøftehauge, Morten K.; Hajizadeh, Nelly R.; Swann, Marcus J.; Pohl, Ehmke

    2015-01-01

    Over the last decades, a wide range of biophysical techniques investigating protein–ligand interactions have become indispensable tools to complement high-resolution crystal structure determinations. Current approaches in solution range from high-throughput-capable methods such as thermal shift assays (TSA) to highly accurate techniques including microscale thermophoresis (MST) and isothermal titration calorimetry (ITC) that can provide a full thermodynamic description of binding events. Surface-based methods such as surface plasmon resonance (SPR) and dual polarization interferometry (DPI) allow real-time measurements and can provide kinetic parameters as well as binding constants. DPI provides additional spatial information about the binding event. Here, an account is presented of new developments and recent applications of TSA and DPI connected to crystallography. PMID:25615858

  11. Advocacy in Action: Annual 2006 DPI/NGO Conference at the United Nations

    ERIC Educational Resources Information Center

    Brown, Nancy

    2007-01-01

    The Association for Childhood Education International (ACEI) was again represented at the annual 2006 DPI/NGO conference, along with 1,600 participants from around the world. The mood this year was somber and quite serious, possibly in response to the uncertainty created by the Middle East crisis that was raging while the conference was taking…

  12. Dutch surgery in Japan.

    PubMed

    van Gulik, Thomas M; Nimura, Yuji

    2005-01-01

    An isolation policy was adopted in feudal Japan from 1639 to 1853 owing to the fear of foreign influence. During those 200 years of isolation, all foreigners were withheld from the country with the exception of the Dutch, who were permitted to establish a trading post on a small island in the Bay of Nagasaki, called Decima. Western culture and science reached the Japanese exclusively through the Dutch on Decima. Health care on Decima was provided by Dutch barber-surgeons, who introduced Western surgical practice in Japan. Official interpreters were the only Japanese allowed on Decima. It was from among these interpreters that the first Japanese surgeons arose who, having mastered the Dutch language, translated several Dutch anatomic and surgical texts. Genpaku Sugita translated a Dutch anatomy textbook into Japanese, which was completed in 1774. This book, entitled Kaitai Shinsho [New Book on Anatomy], was the first Western scientific monograph to be translated entirely into Japanese. Several Dutch surgical schools were founded through which Dutch surgery, known in Japan as "surgery of the red-haired" was propagated. According to the custom of the surgical guilds in Holland, certificates were granted to Japanese apprentices who had completed their training in Dutch surgery. About 60 Dutch surgeons had served on Decima up to 1850, providing the basis for surgery to develop in Japan. Among them, Philipp Franz von Siebold was an exceptional scholar who also had a great impact in making Japanese culture known to the Western world. PMID:15599736

  13. Polymers.

    ERIC Educational Resources Information Center

    Tucker, David C.

    1986-01-01

    Presents an open-ended experiment which has students exploring polymer chemistry and reverse osmosis. This activity involves construction of a polymer membrane, use of it in a simple osmosis experiment, and application of its principles in solving a science-technology-society problem. (ML)

  14. What's Missing in Dutch?

    ERIC Educational Resources Information Center

    Weverink, Meike

    An often-noted contrast between child and adult language is that young children produce sentences both with and without lexical subjects even if subjects are obligatory in the adult system. However, in Dutch, there is no such structural difference between the earliest stages of Dutch child grammar and the adult stage where subjects are concerned.…

  15. Pharmacoscintigraphic and pharmacokinetic evaluation of tobramycin DPI formulations in cystic fibrosis patients.

    PubMed

    Pilcer, Gabrielle; Goole, Jonathan; Van Gansbeke, Bernard; Blocklet, Didier; Knoop, Christiane; Vanderbist, Francis; Amighi, Karim

    2008-02-01

    Tobramycin dry powder formulations were evaluated by gamma scintigraphy and pharmacokinetic methods. In an open single-dose, three-treatment, three-period, cross-over study, nine cystic fibrosis patients received both the two test products and the reference product Tobi (nebulizer solution) in order to assess lung deposition and systemic comparative bioavailability of the two investigational inhaled products versus the marketed inhaled comparator product. The percentage of dose (mean+/-SD) in the whole lung was 53.0+/-10.0% for the tobramycin Form 1, 34.1+/-12.4% for the tobramycin Form 2 and 7.6+/-2.7% for the comparator product Tobi. Lung deposition expressed as a percentage of the nominal dose was thus estimated to be 7.0 and 4.5 times higher for the Tobra Form 1 and Tobra Form 2 than for the Tobi, respectively. Furthermore, the systemic bioavailability (adjusted to correspond to the same drug dose as that of the comparator product deposited in the lung) was found to be 1.6 times higher for the comparator product Tobi than for the two DPI formulations. The principal advantages of the DPI formulations include reduced systemic availability and thus, side effects, and higher dose levels of the drug at the site of drug action. PMID:17574400

  16. PyDPI: freely available python package for chemoinformatics, bioinformatics, and chemogenomics studies.

    PubMed

    Cao, Dong-Sheng; Liang, Yi-Zeng; Yan, Jun; Tan, Gui-Shan; Xu, Qing-Song; Liu, Shao

    2013-11-25

    The rapidly increasing amount of publicly available data in biology and chemistry enables researchers to revisit interaction problems by systematic integration and analysis of heterogeneous data. Herein, we developed a comprehensive python package to emphasize the integration of chemoinformatics and bioinformatics into a molecular informatics platform for drug discovery. PyDPI (drug-protein interaction with Python) is a powerful python toolkit for computing commonly used structural and physicochemical features of proteins and peptides from amino acid sequences, molecular descriptors of drug molecules from their topology, and protein-protein interaction and protein-ligand interaction descriptors. It computes 6 protein feature groups composed of 14 features that include 52 descriptor types and 9890 descriptors, 9 drug feature groups composed of 13 descriptor types that include 615 descriptors. In addition, it provides seven types of molecular fingerprint systems for drug molecules, including topological fingerprints, electro-topological state (E-state) fingerprints, MACCS keys, FP4 keys, atom pair fingerprints, topological torsion fingerprints, and Morgan/circular fingerprints. By combining different types of descriptors from drugs and proteins in different ways, interaction descriptors representing protein-protein or drug-protein interactions could be conveniently generated. These computed descriptors can be widely used in various fields relevant to chemoinformatics, bioinformatics, and chemogenomics. PyDPI is freely available via https://sourceforge.net/projects/pydpicao/. PMID:24047419

  17. Syntactic Persistence in Dutch.

    ERIC Educational Resources Information Center

    Hartsuiker, Robert J.; Kolk, Herman H. J.

    1998-01-01

    Three experiments are reported that showed effects of "structure priming," the tendency to repeat syntactic structure across successive sentences. These effects were demonstrated in Dutch, a previously untested language. All experiments studied spoken sentence production. (Author/JL)

  18. cis regulatory requirements for hypodermal cell-specific expression of the Caenorhabditis elegans cuticle collagen gene dpy-7.

    PubMed Central

    Gilleard, J S; Barry, J D; Johnstone, I L

    1997-01-01

    The Caenorhabditis elegans cuticle collagens are encoded by a multigene family of between 50 and 100 members and are the major component of the nematode cuticular exoskeleton. They are synthesized in the hypodermis prior to secretion and incorporation into the cuticle and exhibit complex patterns of spatial and temporal expression. We have investigated the cis regulatory requirements for tissue- and stage-specific expression of the cuticle collagen gene dpy-7 and have identified a compact regulatory element which is sufficient to specify hypodermal cell reporter gene expression. This element appears to be a true tissue-specific promoter element, since it encompasses the dpy-7 transcription initiation sites and functions in an orientation-dependent manner. We have also shown, by interspecies transformation experiments, that the dpy-7 cis regulatory elements are functionally conserved between C. elegans and C. briggsae, and comparative sequence analysis supports the importance of the regulatory sequence that we have identified by reporter gene analysis. All of our data suggest that the spatial expression of the dpy-7 cuticle collagen gene is established essentially by a small tissue-specific promoter element and does not require upstream activator or repressor elements. In addition, we have found the DPY-7 polypeptide is very highly conserved between the two species and that the C. briggsae polypeptide can function appropriately within the C. elegans cuticle. This finding suggests a remarkably high level of conservation of individual cuticle components, and their interactions, between these two nematode species. PMID:9121480

  19. Na/sup +/ channels as sites of action of the cardioactive agent DPI 201-106 with agonist and antagonist enantiomers

    SciTech Connect

    Romey, G.; Quast, U.; Pauron, D.; Frelin, C.; Renaud, J.F.; Lazdunski, M.

    1987-02-01

    This paper shows the interaction of the cardiotonic agent 4-(3-(4-diphenylmethyl-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile (DPI 201-106) and its optic enantiomers R-DPI (205-429) and S-DPI (205-430) with the Na/sup +/ channel of a variety of excitable cells. Voltage-clamp experiments show that DPI 201-106 acts on neuroblastoma cells and rat cardiac cells. S-DPI (205-430) increases the peak Na/sup +/ current, slows down the kinetics of Na/sup +/ channel inactivation, and is cardiotonic on heart cells. Conversely, R-DPI (205-429) reduces the peak Na/sup +/ current and blocks Na/sup +/ channel activity and cardiac contractions. Binding experiments using radioactively labeled toxins indicate that DPI 201-106 and its enantiomers do not interact with sites already identified for tetrodotoxin or sea anemone and scorpion toxins. DPI 201-106 and its enantiomers inhibit binding of a /sup 3/H-labeled batrachotoxin derivative, (/sup 3/H)batrachotoxinin A 20-..cap alpha..-benzoate, to brain membranes. The dissociation constant of the complex formed between the Na/sup +/ channel and both R-DPI and S-DPI is K/sub d/ approx. 100 nM. /sup 22/Na/sup +/ uptake experiments using different cell types have shown that R and S enantiomers of DPI 201-106 are active on the different Na/sup +/ channel subtypes with similar IC/sub 50/ values. These results are discussed in relation with the cardiotonic properties of DPI 201-106 that are not accompanied by cardiotoxic effects.

  20. A Recurrent Deletion of DPY19L2 Causes Infertility in Man by Blocking Sperm Head Elongation and Acrosome Formation

    PubMed Central

    Harbuz, Radu; Zouari, Raoudha; Pierre, Virginie; Ben Khelifa, Mariem; Kharouf, Mahmoud; Coutton, Charles; Merdassi, Ghaya; Abada, Farid; Escoffier, Jessica; Nikas, Yorgos; Vialard, François; Koscinski, Isabelle; Triki, Chema; Sermondade, Nathalie; Schweitzer, Thérèse; Zhioua, Amel; Zhioua, Fethi; Latrous, Habib; Halouani, Lazhar; Ouafi, Marrakchi; Makni, Mounir; Jouk, Pierre-Simon; Sèle, Bernard; Hennebicq, Sylviane; Satre, Véronique; Viville, Stéphane; Arnoult, Christophe; Lunardi, Joël; Ray, Pierre F.

    2011-01-01

    An increasing number of couples require medical assistance to achieve a pregnancy, and more than 2% of the births in Western countries now result from assisted reproductive technologies. To identify genetic variants responsible for male infertility, we performed a whole-genome SNP scan on patients presenting with total globozoospermia, a primary infertility phenotype characterized by the presence of 100% round acrosomeless spermatozoa in the ejaculate. This strategy allowed us to identify in most patients (15/20) a 200 kb homozygous deletion encompassing only DPY19L2, which is highly expressed in the testis. Although there was no known function for DPY19L2 in humans, previous work indicated that its ortholog in C. elegans is involved in cell polarity. In man, the DPY19L2 region has been described as a copy-number variant (CNV) found to be duplicated and heterozygously deleted in healthy individuals. We show here that the breakpoints of the deletions are located on a highly homologous 28 kb low copy repeat (LCR) sequence present on each side of DPY19L2, indicating that the identified deletions were probably produced by nonallelic homologous recombination (NAHR) between these two regions. We demonstrate that patients with globozoospermia have a homozygous deletion of DPY19L2, thus indicating that DPY19L2 is necessary in men for sperm head elongation and acrosome formation. A molecular diagnosis can now be proposed to affected men; the presence of the deletion confirms the diagnosis of globozoospermia and assigns a poor prognosis for the success of in vitro fertilization. PMID:21397064

  1. Measurement of Time-dependent CP Asymmetries inB0->D(*)pi and B0->Drho Decays

    SciTech Connect

    Aubert, B.

    2006-03-03

    We present updated results on time-dependent CP asymmetries in fully reconstructed B{sup 0} {yields} D{sup (*){+-}}{pi}{sup {-+}} and B{sup 0} {yields} D{sup {+-}}{rho}{sup {-+}} decays in approximately 232 million {Upsilon}(4S) {yields} B{bar B} events collected with the BABAR detector at the PEP-II asymmetric-energy B factory at SLAC. From a time-dependent maximum likelihood fit we obtain for the parameters related to the CP violation angle 2{beta} + {gamma}: a{sup D{pi}} = -0.010 {+-} 0.023 {+-} 0.007, c{sub lep}{sup D{pi}} = -0.033 {+-} 0.042 {+-} 0.012, a{sup D*{pi}} = -0.040 {+-} 0.023 {+-} 0.010, C{sub lep}{sup D*{pi}} = 0.049 {+-} 0.042 {+-} 0.015, a{sup D{rho}} = -0.024 {+-} 0.031 {+-} 0.009, c{sub lep}{sup D{rho}} = -0.098 {+-} 0.055 {+-} 0.018, where the first error is statistical and the second is systematic. Using other measurements and theoretical assumptions, we interpret the results in terms of the angles of the Cabibbo-Kobayashi-Maskawa unitarity triangle and find |sin(2{beta}+{gamma})| > 0.64 (0.40) at 68% (90%) confidence level.

  2. The DPY-30 Domain and Its Flanking Sequence Mediate the Assembly and Modulation of Flagellar Radial Spoke Complexes

    PubMed Central

    Gopal, Radhika; Foster, Kenneth W.

    2012-01-01

    RIIa is known as the dimerization and docking (D/D) domain of the cyclic AMP (cAMP)-dependent protein kinase. However, numerous molecules, including radial spoke protein 2 (RSP2) in Chlamydomonas flagella, also contain an RIIa or a similar DPY-30 domain. To elucidate new roles of D/D domain-containing proteins, we investigated a panel of RSP2 mutants. An RSP2 mutant had paralyzed flagella defective in RSP2 and multiple subunits near the spokehead. New transgenic strains lacking only the DPY-30 domain in RSP2 were also paralyzed. In contrast, motility was restored in strains that lacked only RSP2's calmodulin-binding C-terminal region. These cells swam normally in dim light but could not maintain typical swimming trajectories under bright illumination. In both deletion transgenic strains, the subunits near the spokehead were restored, but their firm attachment to the spokestalk required the DPY-30 domain. We postulate that the DPY-30–helix dimer is a conserved two-prong linker, required for normal motility, organizing duplicated subunits in the radial spoke stalk and formation of a symmetrical spokehead. Further, the dispensable calmodulin-binding region appears to fine-tune the spokehead for regulation of “steering” motility in the green algae. Thus, in general, D/D domains may function to localize molecular modules for both the assembly and modulation of macromolecular complexes. PMID:22851692

  3. A New Direct-Pour In-Mold (DPI) Technology for Producing Ductile and Compacted Graphite Iron Castings.

    SciTech Connect

    Jason Hitchings; Jay R. Hitchings

    2007-07-20

    A new "Direct Pour In-Mold" (DPI) Magnesium treatment technology has been developed that can produce both Nodular and Compacted Graphite iron. The DPI technology converts the standard horizontal runner system into a vertical one, by placing a Magnesium Ferrosilicon treatment alloy and molten metal filter into a specially designed container. The DPI container is easily placed into either vertically or horizontally parted molds, and then a base metal can be poured directly into it. The metal is treated and filtered as it passes through, and then proceeds directly into a runner or casting cavity. Various sizes of containers provide all of the necessary components required to deliver a range of weights of treated and filtered metal at accurate and consistent flow rates. The DPI containers provide energy savings over competing techniques, increased mold yields, very high Magnesium recovery, zero Magnesium fume, and no post inoculation is required. By treating the metal just prior to it entering a casting cavity many other benefits and advantages are also realized.

  4. Identification of DPY19L3 as the C-mannosyltransferase of R-spondin1 in human cells

    PubMed Central

    Niwa, Yuki; Suzuki, Takehiro; Dohmae, Naoshi; Simizu, Siro

    2016-01-01

    R-spondin1 (Rspo1) is a secreted protein that enhances Wnt signaling, which has crucial functions in embryonic development and several cancers. C-mannosylation is a rare type of glycosylation and might regulate secretion, protein–protein interactions, and enzymatic activity. Although human Rspo1 contains 2 predicted C-mannosylation sites, C-mannosylation of Rspo1 has not been reported, nor have its functional effects on this protein. In this study, we demonstrate by mass spectrometry that Rspo1 is C-mannosylated at W153 and W156. Using Lec15.2 cells, which lack dolichol-phosphate-mannose synthesis activity, and mutant Rspo1-expressing cells that replace W153 and W156 by alanine residues, we observed that C-mannosylation of Rspo1 is required for its secretion. Further, the enhancement of canonical Wnt signaling by Rspo1 is regulated by C-mannosylation. Recently DPY19 was reported to be a C-mannosyltransferase in Caenorhabditis elegans, but no C-mannosyltransferases have been identified in any other organism. In gain- and loss-of-function experiments, human DPY19L3 selectively modified Rspo1 at W156 but not W153 based on mass spectrometry. Moreover, knockdown of DPY19L3 inhibited the secretion of Rspo1. In conclusion, we identified DPY19L3 as the C-mannosyltransferase of Rspo1 at W156 and found that DPY19L3-mediated C-mannosylation of Rspo1 at W156 is required for its secretion. PMID:26764097

  5. Dutch euthanasia revisited.

    PubMed

    Fenigsen, R

    1997-01-01

    The results of a follow-up study of euthanasia by the Dutch government, five years after the first study, were published on November 26, 1996. This article provides a detailed review of the two reports comparing and contrasting the statistics cited therein. The author notes that the "rules of careful conduct" proposed by the courts and by the Royal Dutch Society of Medicine were frequently disregarded. Special topics included for the first time in the second study were the notification and non-prosecution procedure, euthanasia of newborns and infants, and assisted suicide in psychiatric practice. The authors of the follow-up report state that it would be desirable to reduce the number of "terminations of life without patients' request," but this must be the common responsibility of the doctor and the patient. They suggest that the person who does not wish to have his life terminated should declare this clearly, in advance, verbally and in writing, preferably in the form of a living will. Involuntary euthanasia was rampant in 1990 and equally rampant in 1995. The author concludes that Dutch doctors who practice euthanasia are not on the slippery slope. From the very beginning, they have been at the bottom. PMID:9479883

  6. Will Dutch Become Flemish? Autonomous Developments in Belgian Dutch

    ERIC Educational Resources Information Center

    Van de Velde, Hans; Kissine, Mikhail; Tops, Evie; van der Harst, Sander; van Hout, Roeland

    2010-01-01

    In this paper a series of studies of standard Dutch pronunciation in Belgium and the Netherlands is presented. The research is based on two speech corpora: a diachronic corpus of radio speech (1935-1995) and a synchronic corpus of Belgian and Netherlandic standard Dutch from different regions at the turn of the millennium. It is shown that two…

  7. Pennsylvania Dutch Crafts and Culture

    ERIC Educational Resources Information Center

    Turner, Dianne

    2008-01-01

    Many people hold two common misconceptions about the Pennsylvania Dutch: first, that these people live exclusively in the state of Pennsylvania; second, that their ancestors came from Holland. However, neither assumption is correct. One can find large Pennsylvania Dutch communities in Mary land, West Virginia, Virginia, the Carolinas, Ohio,…

  8. The Dutch experience.

    PubMed

    Hendin, Herbert

    2002-01-01

    Euthanasia has been legally sanctioned in the Netherlands by a series of court decisions going back to the 1970s. The author discusses the cultural and historical factors that may have contributed to this development. In the past decade, studies sanctioned by the Dutch government reveal that guidelines established for the regulation of euthanasia--a voluntary, well-considered, persistent request, intolerable suffering that cannot be relieved, consultation with a colleague, and reporting of cases--are consistently violated. Of greatest concern is the number of patients who are put to death without their consent--there are more involuntary than voluntary cases. Euthanasia intended originally for the exceptional case has become an accepted way of dealing with the physical and mental distress of serious or terminal illness. In the process palliative care has become one of the casualties while hospice care lags behind that of other countries. Case examples are given. PMID:11925835

  9. Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation

    PubMed Central

    Escoffier, Jessica; Yassine, Sandra; Lee, Hoi Chang; Martinez, Guillaume; Delaroche, Julie; Coutton, Charles; Karaouzène, Thomas; Zouari, Raoudha; Metzler-Guillemain, Catherine; Pernet-Gallay, Karin; Hennebicq, Sylviane; Ray, Pierre F.; Fissore, Rafael; Arnoult, Christophe

    2015-01-01

    We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia (70%) and described that Dpy19l2 knockout (KO) mice faithfully reproduce the human phenotype of globozoospermia making it an excellent model to characterize the molecular physiopathology of globozoospermia. Recent case studies on non-genetically characterized men with globozoospermia showed that phospholipase C, zeta (PLCζ), the sperm factor thought to induce the Ca2+ oscillations at fertilization, was absent from their sperm, explaining the poor fertilization potential of these spermatozoa. Since 30% of globozoospermic men remain genetically uncharacterized, the absence of PLCζ in DPY19L2 globozoospermic men remains to be formally established. Moreover, the precise localization of PLCζ and the reasons underlying its loss during spermatogenesis in globozoospermic patients are still not understood. Herein, we show that PLCζ is absent, or its presence highly reduced, in human and mouse sperm with DPY19L2-associated globozoospermia. As a consequence, fertilization with sperm from Dpy19l2 KO mice failed to initiate Ca2+ oscillations and injected oocytes remained arrested at the metaphase II stage, although a few human oocytes injected with DPY19L2-defective sperm showed formation of 2-pronuclei embryos. We report for the first time the subcellular localization of PLCζ in control human sperm, which is along the inner acrosomal membrane and in the perinuclear theca, in the area corresponding to the equatorial region. Because these cellular components are absent in globozoospermic sperm, the loss of PLCζ in globozoospermic sperm is thus consistent and reinforces the role of PLCζ as an oocyte activation factor necessary for oocyte activation. In our companion article, we showed that chromatin compaction during spermiogenesis in Dpy19l2 KO mouse is defective and leads to sperm DNA damage. Together, these defects explain the poor fertilization potential of DPY19L2

  10. Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.

    PubMed

    Escoffier, Jessica; Yassine, Sandra; Lee, Hoi Chang; Martinez, Guillaume; Delaroche, Julie; Coutton, Charles; Karaouzène, Thomas; Zouari, Raoudha; Metzler-Guillemain, Catherine; Pernet-Gallay, Karin; Hennebicq, Sylviane; Ray, Pierre F; Fissore, Rafael; Arnoult, Christophe

    2015-02-01

    We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia (70%) and described that Dpy19l2 knockout (KO) mice faithfully reproduce the human phenotype of globozoospermia making it an excellent model to characterize the molecular physiopathology of globozoospermia. Recent case studies on non-genetically characterized men with globozoospermia showed that phospholipase C, zeta (PLCζ), the sperm factor thought to induce the Ca(2+) oscillations at fertilization, was absent from their sperm, explaining the poor fertilization potential of these spermatozoa. Since 30% of globozoospermic men remain genetically uncharacterized, the absence of PLCζ in DPY19L2 globozoospermic men remains to be formally established. Moreover, the precise localization of PLCζ and the reasons underlying its loss during spermatogenesis in globozoospermic patients are still not understood. Herein, we show that PLCζ is absent, or its presence highly reduced, in human and mouse sperm with DPY19L2-associated globozoospermia. As a consequence, fertilization with sperm from Dpy19l2 KO mice failed to initiate Ca(2+) oscillations and injected oocytes remained arrested at the metaphase II stage, although a few human oocytes injected with DPY19L2-defective sperm showed formation of 2-pronuclei embryos. We report for the first time the subcellular localization of PLCζ in control human sperm, which is along the inner acrosomal membrane and in the perinuclear theca, in the area corresponding to the equatorial region. Because these cellular components are absent in globozoospermic sperm, the loss of PLCζ in globozoospermic sperm is thus consistent and reinforces the role of PLCζ as an oocyte activation factor necessary for oocyte activation. In our companion article, we showed that chromatin compaction during spermiogenesis in Dpy19l2 KO mouse is defective and leads to sperm DNA damage. Together, these defects explain the poor fertilization potential of DPY19L2

  11. DPY-17 and MUA-3 Interact for Connective Tissue-Like Tissue Integrity in Caenorhabditis elegans: A Model for Marfan Syndrome

    PubMed Central

    Fotopoulos, Pauline; Kim, Jeongho; Hyun, Moonjung; Qamari, Waiss; Lee, Inhwan; You, Young-Jai

    2015-01-01

    mua-3 is a Caenorhabditis elegans homolog of the mammalian fibrillin1, a monogenic cause of Marfan syndrome. We identified a new mutation of mua-3 that carries an in-frame deletion of 131 amino acids in the extracellular domain, which allows the mutants to survive in a temperature-dependent manner; at the permissive temperature, the mutants grow normally without obvious phenotypes, but at the nonpermissive temperature, more than 90% die during the L4 molt due to internal organ detachment. Using the temperature-sensitive lethality, we performed unbiased genetic screens to isolate suppressors to find genetic interactors of MUA-3. From two independent screens, we isolated mutations in dpy-17 as a suppressor. RNAi of dpy-17 in mua-3 rescued the lethality, confirming dpy-17 is a suppressor. dpy-17 encodes a collagen known to genetically interact with dpy-31, a BMP-1/Tolloid-like metalloprotease required for TGFβ activation in mammals. Human fibrillin1 mutants fail to sequester TGFβ2 leading to excess TGFβ signaling, which in turn contributes to Marfan syndrome or Marfan-related syndrome. Consistent with that, RNAi of dbl-1, a TGFβ homolog, modestly rescued the lethality of mua-3 mutants, suggesting a potentially conserved interaction between MUA-3 and a TGFβ pathway in C. elegans. Our work provides genetic evidence of the interaction between TGFβ and a fibrillin homolog, and thus provides a simple yet powerful genetic model to study TGFβ function in development of Marfan pathology. PMID:25917920

  12. Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development

    PubMed Central

    Yassine, Sandra; Escoffier, Jessica; Martinez, Guillaume; Coutton, Charles; Karaouzène, Thomas; Zouari, Raoudha; Ravanat, Jean-Luc; Metzler-Guillemain, Catherine; Lee, Hoi Chang; Fissore, Rafael; Hennebicq, Sylviane; Ray, Pierre F.; Arnoult, Christophe

    2015-01-01

    We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia. Non-genetically characterized cases of globozoospermia were associated with DNA alterations, suggesting that DPY19L2-dependent globozoospermia may be associated with poor DNA quality. However the origins of such defects have not yet been characterized and the consequences on the quality of embryos generated with globozoospermic sperm remain to be determined. Using the mouse model lacking Dpy19l2, we compared several key steps of nuclear compaction. We show that the kinetics of appearance and disappearance of the histone H4 acetylation waves and of transition proteins are defective. More importantly, the nuclear invasion by protamines does not occur. As a consequence, we showed that globozoospermic sperm presented with poor sperm chromatin compaction and sperm DNA integrity breakdown. We next assessed the developmental consequences of using such faulty sperm by performing ICSI. We showed in the companion article that oocyte activation (OA) with globozoospermic sperm is very poor and due to the absence of phospholipase Cζ; therefore artificial OA (AOA) was used to bypass defective OA. Herein, we evaluated the developmental potential of embryos generated by ICSI + AOA in mice. We demonstrate that although OA was fully rescued, preimplantation development was impaired when using globozoospermic sperm. In human, a small number of embryos could be generated with sperm from DPY19L2-deleted patients in the absence of AOA and these embryos also showed a poor developmental potential. In conclusion, we show that chromatin compaction during spermiogenesis in Dpy19l2 KO mouse is defective and leads to sperm DNA damage. Most of the DNA breaks were already present when the sperm reached the epididymis, indicating that they occurred inside the testis. This result thus suggests that testicular sperm extraction in Dpy19l2-dependent globozoospermia is not recommended. These defects may

  13. Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development.

    PubMed

    Yassine, Sandra; Escoffier, Jessica; Martinez, Guillaume; Coutton, Charles; Karaouzène, Thomas; Zouari, Raoudha; Ravanat, Jean-Luc; Metzler-Guillemain, Catherine; Lee, Hoi Chang; Fissore, Rafael; Hennebicq, Sylviane; Ray, Pierre F; Arnoult, Christophe

    2015-02-01

    We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia. Non-genetically characterized cases of globozoospermia were associated with DNA alterations, suggesting that DPY19L2-dependent globozoospermia may be associated with poor DNA quality. However the origins of such defects have not yet been characterized and the consequences on the quality of embryos generated with globozoospermic sperm remain to be determined. Using the mouse model lacking Dpy19l2, we compared several key steps of nuclear compaction. We show that the kinetics of appearance and disappearance of the histone H4 acetylation waves and of transition proteins are defective. More importantly, the nuclear invasion by protamines does not occur. As a consequence, we showed that globozoospermic sperm presented with poor sperm chromatin compaction and sperm DNA integrity breakdown. We next assessed the developmental consequences of using such faulty sperm by performing ICSI. We showed in the companion article that oocyte activation (OA) with globozoospermic sperm is very poor and due to the absence of phospholipase Cζ; therefore artificial OA (AOA) was used to bypass defective OA. Herein, we evaluated the developmental potential of embryos generated by ICSI + AOA in mice. We demonstrate that although OA was fully rescued, preimplantation development was impaired when using globozoospermic sperm. In human, a small number of embryos could be generated with sperm from DPY19L2-deleted patients in the absence of AOA and these embryos also showed a poor developmental potential. In conclusion, we show that chromatin compaction during spermiogenesis in Dpy19l2 KO mouse is defective and leads to sperm DNA damage. Most of the DNA breaks were already present when the sperm reached the epididymis, indicating that they occurred inside the testis. This result thus suggests that testicular sperm extraction in Dpy19l2-dependent globozoospermia is not recommended. These defects may

  14. A Homozygous Deletion of the DPY19l2 Gene is a Cause of Globozoospermia in Men from the Republic of Macedonia

    PubMed Central

    Noveski, P; Madjunkova, S; Maleva, I; Sotiroska, V; Petanovski, Z; Plaseska-Karanfilska, D

    Globozoospermia is a rare but severe teratozoospermia, characterized by ejaculates consisting completely of round-headed spermatozoa that lack an acrosome or, in partial globozoospermia, containing a variable proportion (20.0–90.0%) of acrosomeless spermatozoa. Men that are affected with total globozoospermia are infertile, and even the application of intracytoplasmic sperm injection (ICSI) has met with disappointingly low success rates. In humans, several case reports of globozoospermia have demonstrated that two or more siblings were affected in each family, which suggested a genetic component to this disease. Currently, three genes are known to be associated with total globozoospermia in humans, SPATA16 , PICK1 and DPY19L2 genes. Mutations in SPATA16 and PICK1 are rare causes of globozoospermia, found in only one patient each. Several studies have suggested that DPY19L2 mutations are the major cause of globozoospermia in patients from different ethnic origins and different geographic regions. The most common DPY19L2 mutation is the 200 kb deletion arising from a nonallelic homologous recombination (NAHR) between the flanking low copy repeats (LCRs). Here we describe the presence of a homozygous deletion of the DPY19L2 gene in two infertile Macedonian patients with 100.0% round headed spermatozoa, thus suggesting that this deletion represents a major cause of globozoospermia among Macedonian men. PMID:24265589

  15. Dutch museum marks Einstein anniversary

    NASA Astrophysics Data System (ADS)

    van Calmthout, Matijn

    2016-01-01

    A new painting of Albert Einstein's field equation from his 1915 general theory of relativity was unveiled in a ceremony in November 2015 by the Dutch physicist Robbert Dijkgraaf, who is director of the Princeton Institute for Advanced Study in the US.

  16. [Dutch parliament legitimizes harmful quackery].

    PubMed

    van Dam, Frits S A M; Renckens, Cees N M

    2010-01-01

    The Dutch parliament has recently accepted a tax law in which certain groups of alternative therapists can be exempt from VAT. To be eligible for this VAT exemption, the disciplines to which the therapists belong have to meet certain training requirements. In this article it is contended, in agreement with the Royal College of Physicians in the UK, that statutory regulation is inappropriate for disciplines whose therapies are neither of proved benefit nor appropriately tested. It legitimizes harmful therapies. This is illustrated by two serious accidents, previously described in this journal, caused by a chiropractor and a craniosacral therapist. PMID:20298623

  17. [Teledermatology within Dutch nursing homes].

    PubMed

    Lubeek, Satish F K; Mommers, Roland J M; van der Geer, Eric R; van de Kerkhof, Peter C M; Gerritsen, Marie-Jeanne Rianne P

    2016-06-01

    Skin problems are common within the nursing home population and could have a significant impact on quality of life. As a form of long-distance consultation teledermatology offers several potential benefits within this frail population. In this review we discuss several aspects of teledermatology, especially in relation to the nursing home population. Several studies demonstrated that teledermatology is a cost-effective and easy-to-use consultation method, which could significantly reduce the amount of hospital visits. However, teledermatology is only used in a limited number of Dutch nursing homes in daily practice due to several factors. For the optimal implementation of teledermatological consultation there are some important logistical, legal and financial framework conditions. In conclusion, teledermatology has a lot to offer within the nursing home population and therefore teledermatology will hopefully be increasingly used in daily practice within the near future. PMID:27098424

  18. A case against Dutch euthanasia.

    PubMed

    Fenigsen, Richard

    1989-01-01

    The growing acceptance of voluntary active euthanasia by the Dutch is examined in relation to the plastic cards requesting active euthanasia carried by many people in The Netherlands, public opinion polls, and support by leading medical figures of the movement to legalize euthanasia. The author draws upon his experience as a hospital doctor to condemn the practice of active euthanasia, arguing that its voluntariness is often counterfeit and always questionable, that it is inseparable from overtly involuntary forms of euthanasia, and that its promise of sparing the sick person agony is false. "Voluntary" euthanasia also brings an ominous change in society because of the message it sends to the elderly and sick, the weak and the dependent; because the fallibility of medical judgments are inconsistent with the irreversibility of the act; and because the fallacious reasoning of the philosophy threatens to cause irreparable damage to the medical profession. PMID:11650123

  19. Therapeutic comparison of a new budesonide/formoterol pMDI with budesonide pMDI and budesonide/formoterol DPI in asthma

    PubMed Central

    Morice, A H; Peterson, S; Beckman, O; Osmanliev, D

    2007-01-01

    Background Budesonide/formoterol is an effective treatment for both asthma and chronic obstructive pulmonary disease. This study compared the efficacy and safety of a novel hydrofluoroalkane (HFA) pressurised metered-dose inhaler (pMDI) formulation of budesonide/formoterol with that of budesonide pMDI and budesonide/formoterol dry-powder inhaler (DPI; Turbuhaler®). Methods This was a 12-week, multinational, randomised, double-blind, double-dummy study involving patients aged ≥ 12 years with asthma. All patients had a forced expiratory volume in 1 s of 50–90% predicted normal and were inadequately controlled on inhaled corticosteroids (500–1600 mu g/day) alone. Following a 2-week run-in, during which they received their usual medication, patients were randomised (two inhalations twice daily) to budesonide pMDI 200 mu g, budesonide/formoterol DPI 160/4.5 mu g or budesonide/formoterol pMDI 160/4.5 mu g. The primary efficacy end-point was change from baseline in morning peak expiratory flow (PEF). Results In total, 680 patients were randomised, of whom 668 were included in the primary analysis. Therapeutically equivalent increases in morning PEF were observed with budesonide/formoterol pMDI (29.3 l/min) and budesonide/formoterol DPI (32.0 l/min) (95% confidence interval: −10.4 to 4.9; p = 0.48). The increase in morning PEF with budesonide/formoterol pMDI was significantly higher than with budesonide pMDI (+28.7 l/min; p < 0.001). Similar improvements with budesonide/formoterol pMDI vs. budesonide pMDI were seen for all secondary efficacy end-points. Both combination treatments were similarly well tolerated. Conclusions Budesonide/formoterol, administered via the HFA pMDI or DPI, is an effective and well-tolerated treatment for adult and adolescent patients with asthma, with both devices being therapeutically equivalent. PMID:17887990

  20. Dutch research reforms cause a stir

    NASA Astrophysics Data System (ADS)

    van Calmthout, Martijn

    2015-02-01

    All 69 winners of the Spinoza prize - the highest award in Dutch science - have signed a petition against proposed reforms to the country's leading funding agency, the Netherlands Organisation for Scientific Research (NWO).

  1. [Dutch government invests in existing biobanks].

    PubMed

    Brandsma, Margreet; van Ommen, Gert-Jan B; Wijmenga, Cisca; Kiemeney, Lambertus A

    2010-01-01

    Modern research, aimed at discovering factors that influence health and disease, requires large collections of data and samples. Collaboration between biobanks is therefore essential. The Dutch hub in the network of biobanks, the Biobanking and Biomolecular Resources Research Infrastructure (BBMRI-NL), is one of the major Dutch biobanking initiatives. It is sponsored by the Dutch government through the Netherlands Organization for Scientific Research (NWO). BBMRI-NL sets up collaboration between approximately 150 existing clinical and population biobanks in the Netherlands, and forms the link with the European BBMRI initiative. BBMRI-NL aims at enrichment and harmonization of existing Dutch biobanks, at data management and analysis, and at laying the legal, social and ethical foundations, in order to improve access and inter-operability, and to render the information and organization up to date. Other major Dutch initiatives are String of Pearls and LifeLines. Together these will create the conditions needed for Dutch researchers to further develop their strong position in the international biobanking field. PMID:21029488

  2. Ethnic Identity, Externalizing Problem Behaviour and the Mediating Role of Self-Esteem among Dutch, Turkish-Dutch and Moroccan-Dutch Adolescents

    ERIC Educational Resources Information Center

    Wissink, Inge B.; Dekovic, Maja; Yagmur, Sengul; Stams, Geert Jan; de Haan, Mariette

    2008-01-01

    The present study examined whether self-esteem mediates the relationship between two aspects of ethnic identity (i.e. ethnic identity exploration and ethnic identity commitment-affirmation) and externalizing problem behaviour in Dutch, Turkish-Dutch and Moroccan-Dutch adolescents living in the Netherlands. A total number of 345 adolescents (115…

  3. Polymer films

    DOEpatents

    Granick, Steve; Sukhishvili, Svetlana A.

    2004-05-25

    A film contains a first polymer having a plurality of hydrogen bond donating moieties, and a second polymer having a plurality of hydrogen bond accepting moieties. The second polymer is hydrogen bonded to the first polymer.

  4. Polymer films

    DOEpatents

    Granick, Steve; Sukhishvili, Svetlana A.

    2008-12-30

    A film contains a first polymer having a plurality of hydrogen bond donating moieties, and a second polymer having a plurality of hydrogen bond accepting moieties. The second polymer is hydrogen bonded to the first polymer.

  5. DNA barcoding of Dutch birds

    PubMed Central

    Aliabadian, Mansour; Beentjes, Kevin K.; Roselaar, C.S. (Kees); van Brandwijk, Hans; Nijman, Vincent; Vonk, Ronald

    2013-01-01

    Abstract The mitochondrial cytochrome c oxidase subunit I (COI) can serve as a fast and accurate marker for the identification of animal species, and has been applied in a number of studies on birds. We here sequenced the COI gene for 387 individuals of 147 species of birds from the Netherlands, with 83 species being represented by > 2 sequences. The Netherlands occupies a small geographic area and 95% of all samples were collected within a 50 km radius from one another. The intraspecific divergences averaged 0.29% among this assemblage, but most values were lower; the interspecific divergences averaged 9.54%. In all, 95% of species were represented by a unique barcode, with 6 species of gulls and skua (Larus and Stercorarius) having at least one shared barcode. This is best explained by these species representing recent radiations with ongoing hybridization. In contrast, one species, the Lesser Whitethroat Sylvia curruca showed deep divergences, averaging 5.76% and up to 8.68% between individuals. These possibly represent two distinct taxa, S. curruca and S. blythi, both clearly separated in a haplotype network analysis. Our study adds to a growing body of DNA barcodes that have become available for birds, and shows that a DNA barcoding approach enables to identify known Dutch bird species with a very high resolution. In addition some species were flagged up for further detailed taxonomic investigation, illustrating that even in ornithologically well-known areas such as the Netherlands, more is to be learned about the birds that are present. PMID:24453549

  6. Perceived antecedents of marital satisfaction among Turkish, Turkish-Dutch, and Dutch couples.

    PubMed

    Celenk, Ozgur; van de Vijver, Fons J R

    2013-01-01

    We studied mainstream couples in The Netherlands and Turkey as well as Turkish-Dutch immigrant couples to address cultural factors associated with marital satisfaction. A total of 13 Turkish (mainstream couples living in Turkey), 19 Turkish-Dutch (Turkish immigrant couples living in The Netherlands), and 17 Dutch (mainstream couples living in The Netherlands) married dyads (total of 98 individuals) were independently interviewed about positive and negative characteristics of marriages, determinants of general marital satisfaction and dissatisfaction, spousal communication, marital conflict, and marital roles. Multivariate tests revealed ethnic group differences on all marriage-related domains except the conflict resolution strategies. However, univariate analyses showed differences in few themes within domains; main differences were assessed between the Turkish/Turkish-Dutch (who put more emphasis on children and economical aspects) and Dutch couples (who put more emphasis on behavior, and personality of the spouse, reciprocity, emotional sharing, and psychological roles). Turkish-Dutch couples were more similar to Turkish than to Dutch couples. Results were discussed in light of the socioeconomic development and cultural value theories, which are believed to provide a useful framework for understanding the role of culture in marital satisfaction. PMID:23126343

  7. Measurement of time-dependent CP asymmetries and constraints on sin(2beta+gamma) with partial reconstruction of B0-->D*-/+pi+/- decays.

    PubMed

    Aubert, B; Barate, R; Boutigny, D; Couderc, F; Gaillard, J-M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Knowles, D J; Morgan, S E; Penny, R C; Watson, A T; Watson, N K; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schmuecker, H; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Mackay, C; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; McKemey, A K; Teodorescu, L; Blinov, V E; Bukin, A D; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Gary, J W; Layter, J; Shen, B C; Wang, K; del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Beringer, J; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Spradlin, P; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Erwin, R J; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Roy, J; Smith, J G; van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Dubitzky, R S; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Wilden, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Khan, A; Lavin, D; Muheim, F; Playfer, S; Swain, J E; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Morii, M; Won, E; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Eschrich, I; Gaillard, J R; Morton, G W; Nash, J A; Taylor, G P; Grenier, G J; Lee, S-J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Diberder, F Le; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Brigljević, V; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Coleman, J P; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Shorthouse, H W; Vidal, P B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Jackson, F; Lafferty, G D; Lyon, A J; Weatherall, J H; Williams, J C; Farbin, A; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Cote-Ahern, D; Taras, P; Nicholson, H; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; LoSecco, J M; Gabriel, T A; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Wong, Q K; Brau, J; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; de la Vaissière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; Stark, J; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Anulli, F; Biasini, M; Peruzzi, I M; Pioppi, M; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Del Gamba, V; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Tanaka, H A; Varnes, E W; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; SafaiTehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P-F; Hamel de Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yeche, Ch; Zito, M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Cristinziani, M; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Elsen, E E; Field, R C; Glanzman, T; Gowdy, S J; Grauges-Pous, E; Hadig, T; Halyo, V; Hryn'ova, T; Innes, W R; Jessop, C P; Kelsey, M H; Kim, P; Kocian, M L; Langenegger, U; Leith, D W G S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, M; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Johnson, J R; Kutter, P E; Li, H; Liu, R; Di Lodovico, F; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

    2004-06-25

    We present a measurement of time-dependent CP-violating asymmetries in decays of neutral B mesons to the final states D(*-/+)pi(+/-), using approximately 82x10(6) BBmacr; events recorded by the BABAR experiment at the PEP-II e(+)e(-) storage ring. Events containing these decays are selected with a partial reconstruction technique, in which only the high-momentum pi(+/-) from the B decay and the low-momentum pi(-/+) from the D(*-/+) decay are used. We measure the amplitude of the asymmetry to be -0.063+/-0.024(stat)+/-0.014(syst) and compute bounds on |sin((2beta+gamma)|. PMID:15244996

  8. EFQM approach and the Dutch Quality Award.

    PubMed

    Nabitz, U W; Klazinga, N S

    1999-01-01

    Different approaches to improve quality are used in organizations delivering health care. Donabedian introduced structure, process and outcome, from which other approaches like self-assessment, accreditation, visitation, International Standards Organisation (ISO) and European Foundation for Quality Management (EFQM) can be aligned. The EFQM model is one such approach that has been adopted and adapted by the Dutch Institute for Quality Management. This article describes the background and progress relating to the use of the EFQM business excellence model within Dutch health care organizations. In addition the process for applying for the European Quality Award and the Dutch Quality Award are described in detail. Finally, the reader is enlightened regarding the work of the European ExPeRT research group who are promoting the use of quality models within health care. PMID:10537859

  9. Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxical excess of duplications over deletions in the general population.

    PubMed

    Coutton, Charles; Abada, Farid; Karaouzene, Thomas; Sanlaville, Damien; Satre, Véronique; Lunardi, Joël; Jouk, Pierre-Simon; Arnoult, Christophe; Thierry-Mieg, Nicolas; Ray, Pierre F

    2013-03-01

    We demonstrated previously that 75% of infertile men with round, acrosomeless spermatozoa (globozoospermia) had a homozygous 200-Kb deletion removing the totality of DPY19L2. We showed that this deletion occurred by Non-Allelic Homologous Recombination (NAHR) between two homologous 28-Kb Low Copy Repeats (LCRs) located on each side of the gene. The accepted NAHR model predicts that inter-chromatid and inter-chromosome NAHR create a deleted and a duplicated recombined allele, while intra-chromatid events only generate deletions. Therefore more deletions are expected to be produced de novo. Surprisingly, array CGH data show that, in the general population, DPY19L2 duplicated alleles are approximately three times as frequent as deleted alleles. In order to shed light on this paradox, we developed a sperm-based assay to measure the de novo rates of deletions and duplications at this locus. As predicted by the NAHR model, we identified an excess of de novo deletions over duplications. We calculated that the excess of de novo deletion was compensated by evolutionary loss, whereas duplications, not subjected to selection, increased gradually. Purifying selection against sterile, homozygous deleted men may be sufficient for this compensation, but heterozygously deleted men might also suffer a small fitness penalty. The recombined alleles were sequenced to pinpoint the localisation of the breakpoints. We analysed a total of 15 homozygous deleted patients and 17 heterozygous individuals carrying either a deletion (n = 4) or a duplication (n = 13). All but two alleles fell within a 1.2-Kb region central to the 28-Kb LCR, indicating that >90% of the NAHR took place in that region. We showed that a PRDM9 13-mer recognition sequence is located right in the centre of that region. Our results therefore strengthen the link between this consensus sequence and the occurrence of NAHR. PMID:23555282

  10. Fine Characterisation of a Recombination Hotspot at the DPY19L2 Locus and Resolution of the Paradoxical Excess of Duplications over Deletions in the General Population

    PubMed Central

    Coutton, Charles; Abada, Farid; Karaouzene, Thomas; Sanlaville, Damien; Satre, Véronique; Lunardi, Joël; Jouk, Pierre-Simon; Arnoult, Christophe; Thierry-Mieg, Nicolas; Ray, Pierre F.

    2013-01-01

    We demonstrated previously that 75% of infertile men with round, acrosomeless spermatozoa (globozoospermia) had a homozygous 200-Kb deletion removing the totality of DPY19L2. We showed that this deletion occurred by Non-Allelic Homologous Recombination (NAHR) between two homologous 28-Kb Low Copy Repeats (LCRs) located on each side of the gene. The accepted NAHR model predicts that inter-chromatid and inter-chromosome NAHR create a deleted and a duplicated recombined allele, while intra-chromatid events only generate deletions. Therefore more deletions are expected to be produced de novo. Surprisingly, array CGH data show that, in the general population, DPY19L2 duplicated alleles are approximately three times as frequent as deleted alleles. In order to shed light on this paradox, we developed a sperm-based assay to measure the de novo rates of deletions and duplications at this locus. As predicted by the NAHR model, we identified an excess of de novo deletions over duplications. We calculated that the excess of de novo deletion was compensated by evolutionary loss, whereas duplications, not subjected to selection, increased gradually. Purifying selection against sterile, homozygous deleted men may be sufficient for this compensation, but heterozygously deleted men might also suffer a small fitness penalty. The recombined alleles were sequenced to pinpoint the localisation of the breakpoints. We analysed a total of 15 homozygous deleted patients and 17 heterozygous individuals carrying either a deletion (n = 4) or a duplication (n = 13). All but two alleles fell within a 1.2-Kb region central to the 28-Kb LCR, indicating that >90% of the NAHR took place in that region. We showed that a PRDM9 13-mer recognition sequence is located right in the centre of that region. Our results therefore strengthen the link between this consensus sequence and the occurrence of NAHR. PMID:23555282

  11. Dutch/Flemish in the North of France.

    ERIC Educational Resources Information Center

    Ryckeboer, Hugo

    2002-01-01

    Discusses Dutch in the Northern France, specifically the historical retreat of Dutch from Pas-de-Calais, historical evolution of the language situation in the Department du Nord, reactions to official language policy and language loss, characteristics of Flemish in France, alienation from other Dutch dialects by communicative isolation, linguistic…

  12. An Intermediate-Advanced Level Dutch Refresher Course.

    ERIC Educational Resources Information Center

    English Language Services, Inc., Washington, DC.

    This refresher course in Dutch consists of eight volumes (Books I-IV, each in two parts). Book I, which begins on the intermediate level, presents the sound system of Dutch with accompanying drills. These provide practice in sound-to-spelling correspondence, and contrastive English-Dutch phonology. Books II and III are comprised of six units of…

  13. The Dutch Euthanasia Act: recent legal developments.

    PubMed

    Legemaate, Johan; Bolt, Ineke

    2013-12-01

    The Dutch Termination of Life on Request and Assisted Suicide Act [Wet toetsing levensbeëindiging op verzoek en hulp bij zelfdoding (Wtl)] came into force in 2002. Its aim is to increase the degree of due care exercised by physicians when terminating a patient's life and to provide a legal framework within which physicians account for their actions in such cases. On the basis of the second evaluation of the Act, published in December 2012, this article provides an overview of the most recent legal developments regarding the Dutch Euthanasia Act. Special attention is given to patients with dementia, psychiatric patients and patient who are "weary of life". PMID:24437331

  14. Learning Styles of Chinese and Dutch Students Compared within the Context of Dutch Higher Education in Life Sciences

    ERIC Educational Resources Information Center

    Biemans, Harm; Van Mil, Marc

    2008-01-01

    This study investigated the extent to which the learning styles of Chinese students differ from those of Dutch students. The study was conducted within the context of English language Bachelor of Science programmes that Wageningen University offers together with China Agricultural University to Dutch and Chinese students. Sixteen Dutch students…

  15. Delinquent Behavior of Dutch Rural Adolescents

    ERIC Educational Resources Information Center

    Weenink, Don

    2011-01-01

    This article compares Dutch rural and non-rural adolescents' delinquent behavior and examines two social correlates of rural delinquency: communal social control and traditional rural culture. The analyses are based on cross-sectional data, containing 3,797 participants aged 13-18 (48.7% females). The analyses show that rural adolescents are only…

  16. Dutch Universities' Joint Aid to Vietnam

    ERIC Educational Resources Information Center

    Higher Education and Research in the Netherlands, 1975

    1975-01-01

    A survey is presented of the joint aid in the reconstruction of North and South Vietnam provided by Dutch universities. The hospital project, solid matter physics project, micro-electronics project, agricultural project and dentistry project are defined. (Author/PG)

  17. Government as Electronic Publishers? The Dutch Case.

    ERIC Educational Resources Information Center

    Bouwman, Harry; Nouwens, John

    1999-01-01

    Discussion of the accessibility of government information focuses on how the Dutch government has tried to improve accessibility in six particular cases of electronic publishing. Topics include public-private partnerships, technological barriers of accessibility, outsourcing, and decentralization. (Author/LRW)

  18. Dutch national rainfallradar project: a unique corporation

    NASA Astrophysics Data System (ADS)

    Schuurmans, Hanneke; Maarten Verbree, Jan; Leijnse, Hidde; van Heeringen, Klaas-Jan; Uijlenhoet, Remko; Bierkens, Mark; van de Giesen, Nick; Gooijer, Jan; van den Houten, Gert

    2013-04-01

    Since January 2013 Dutch watermanagers have access to innovative high-quality rainfall data. This product is innovative because of the following reasons. (i) The product is developed in a 'golden triangle' construction - corporation between government, business and research institutes. (ii) Second the rainfall products are developed according to the open-source GPL license. The initiative comes from a group of water boards in the Netherlands that joined their forces to fund the development of a new rainfall product. Not only data from Dutch radar stations (as is currently done by the Dutch meteorological organization KNMI) is used but also data from radars in Germany and Belgium. After a radarcomposite is made, it is adjusted according to data from raingauges (ground truth). This results in 9 different rainfall products that give for each moment the best rainfall data. This data will be used, depending on the end-user for several applications: (i) forecasts: input for flood early warning systems, (ii) water system analysis: hydrological model input, (iii) optimization: real time control and (iv) investigation of incidents: in case of flooding, who's responsible. The latter is mainly insight in the return period of heavy rainfall events. More info (in Dutch): www.nationaleregenradar.nl

  19. Management Development from a Dutch Perspective.

    ERIC Educational Resources Information Center

    Paauwe, Jaap, Ed.; Williams, Roger, Ed.

    2001-01-01

    Includes "Seven Key Issues for Management Development" (Paauwe, Williams); "Typology of Management Development" (Jansen, van der Velde, Mul); "Management Development at Royal Dutch/Shell" (Mahieu); "Management Development in Unilever" (Reitsma); "International Co-ordination and Management Development" (Hoeksema, de Jong); "Breaking in of New…

  20. National identification of Dutch youth: an exploratory study.

    PubMed

    Oppenheimer, Louis

    2011-06-01

    246 Dutch participants aged 8, 10, 12, 14, and 16 years were presented with the Strength of Identification Scale (SoIS; Barrett, 2007) and the National Identity scale based on Cultural and Historical achievements (NICH; derived from the NATID, Keillor & Hult, 1999). The study aimed to examine the extent and nature of Dutch children and adolescents' identification with The Netherlands and to explore whether changes in aspects of national identification are evident across age. Already at age 8 years children identify themselves with the Dutch nation and with increasing age national identification becomes primarily determined by the extent that participants consider themselves to be Dutch and show positive affect towards the Dutch nation. Identification on the basis of cultural and historical achievements of the Dutch people became less evident following the age of 10 years although Dutch historical and cultural achievements contributed significantly to the extent of national identification. PMID:20673993

  1. Microgravity Polymers

    NASA Technical Reports Server (NTRS)

    1986-01-01

    A one-day, interactive workshop considering the effects of gravity on polymer materials science was held in Cleveland, Ohio, on May 9, 1985. Selected programmatic and technical issues were reviewed to introduce the field to workshop participants. Parallel discussions were conducted in three disciplinary working groups: polymer chemistry, polymer physics, and polymer engineering. This proceedings presents summaries of the workshop discussions and conclusions.

  2. Measurement of time-dependent CP asymmetries in B0-->D(*)+/-pi-/+ decays and constraints on sin(2beta+gamma).

    PubMed

    Aubert, B; Barate, R; Boutigny, D; Gaillard, J-M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Knowles, D J; Morgan, S E; Penny, R C; Watson, A T; Watson, N K; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schmuecker, H; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Mackay, C; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; McKemey, A K; Teodorescu, L; Blinov, V E; Bukin, A D; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Gary, J W; Layter, J; Shen, B C; Wang, K; del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Kuznetsova, N; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Beringer, J; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Erwin, R J; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Roy, J; Smith, J G; van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Dubitzky, R S; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Wilden, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Khan, A; Lavin, D; Muheim, F; Playfer, S; Swain, J E; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Biasini, M; Calcaterra, A; de Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Pioppi, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Morii, M; Won, E; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Eschrich, I; Gaillard, J R; Morton, G W; Nash, J A; Sanders, P; Taylor, G P; Grenier, G J; Lee, S-J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Brigljević, V; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Coleman, J P; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Shorthouse, H W; Vidal, P B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Jackson, F; Lafferty, G D; Lyon, A J; Weatherall, J H; Williams, J C; Farbin, A; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Cote-Ahern, D; Taras, P; Nicholson, H; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; LoSecco, J M; Gabriel, T A; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Wong, Q K; Brau, J; Frey, R; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; de la Vaissière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; Stark, J; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Del Gamba, V; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Tanaka, H A; Varnes, E W; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Tehrani, F Safai; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P-F; Hamel de Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yeche, Ch; Zito, M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Coupal, D P; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Field, R C; Glanzman, T; Gowdy, S J; Grauges-Pous, E; Hadig, T; Halyo, V; Hryn'ova, T; Innes, W R; Jessop, C P; Kelsey, M H; Kim, P; Kocian, M L; Langenegger, U; Leith, D W G S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, M; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Johnson, J R; Kutter, P E; Li, H; Liu, R; Di Lodovico, F; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

    2004-06-25

    We present a measurement of CP-violating asymmetries in fully reconstructed B0-->D(*)+/-pi-/+ decays in approximately 88 x 10(6) upsilon(4S)-->BBmacr; decays collected with the BABAR detector at the PEP-II asymmetric-energy B factory at SLAC. From a time-dependent maximum-likelihood fit we obtain the following for the CP-violating parameters: a=-0.022+/-0.038 (stat)+/-0.020 (syst), a*=-0.068+/-0.038 (stat)+/-0.020 (syst), c(lep)=+0.025+/-0.068 (stat)+/-0.033 (syst), and c*(lep)=+0.031+/-0.070 (stat)+/-0.033 (syst). Using other measurements and theoretical assumptions we interpret the results in terms of the angles of the Cabibbo-Kobayashi-Maskawa unitarity triangle, and find |sin((2beta+gamma)|>0.69 at 68% confidence level. We exclude the hypothesis of no CP violation [sin(2beta+gamma)=0] at 83% confidence level. PMID:15244995

  3. The bilateral action between EQ14-2-14 gemini surfactant and bovine serum albumin by DPI and 1H NMR

    NASA Astrophysics Data System (ADS)

    Wu, Gang; Jiang, Xiaohui; Zhou, Limei; Yang, Lijun; Wang, Ya; Xia, Guangqiang; Chen, Zhengjun; Duan, Ming

    2013-08-01

    Gemini surfactant diglycol bis-N-tetradecyl nicotinate dibromide (designed as EQ14-2-14) has been synthesized. The interaction between EQ14-2-14 and bovine serum albumin (BSA) was studied by dual polarization interferometry (DPI), proton nuclear magnetic resonance spectroscopy (1H NMR), Fourier transform infrared spectroscopy (FTIR) and molecular docking. Owing to the binding of EQ14-2-14, the thickness and mass of BSA increased; refractive index (RI) and density firstly raised and then tended to a plateau. In addition, a decrease of α-helix was observed from 54.01% to 31.56% with an increase in random structure from 7.86% to 21.76%. Due to BSA intertwining, the proton resonance signals of EQ14-2-14 shifted up-field and relaxation time decreased with increasing concentration of BSA. The study of molecular docking indicated that EQ14-2-14 embedded into subdomain II of BSA by π-π stacking between the electron-deficit pyridinium rings in EQ14-2-14 and the electron-abundant pyrrole ring in Trp residues of BSA, by hydrogen bonding and by hydrophobic interaction. Therefore the present work offers a whole view of the interaction of BSA with a new gemini surfactant.

  4. Investment and regulation: the Dutch experience

    SciTech Connect

    Haffner, Robert; Helmer, Dorine; van Til, Harry

    2010-06-15

    Theoretical studies on the relationship between incentive regulation and investment in network industries generally point out that incentive regulation has a negative impact on investment. However, empirical evidence in this area is scarce. An analysis suggests that in the Dutch electricity and gas networks since 2001, incentive regulation has ensured a more rational and professional approach towards investments, with investment levels coming down somewhat at the start of the regulation but picking up later on. (author)

  5. Dutch chemical producers pledge emissions cuts

    SciTech Connect

    Chynoweth, E.; Schoenmakers, J.

    1993-02-24

    Dutch chemical producers have negotiated a long-term agreement with government ministries to reduce emissions of a wide range of chemicals. Industry association Vereniging van de Nederlandse Chemische Industrie (VNCI; Leidschendam) says implementing the commitment will cost companies Dfl 10 billion ($5.4 billion) between 1993 and 2000. VNCI technical director Wim Quik welcomes the accord, which he describes as a management contract, saying, Rather than have legislation, there is a certain adjustment available. Peter Santen, managing director of midsized chemicals player Cindu Chemicals (Uithoorn, the Netherlands) voices some concern about the details of the accord, but adds, we are flexible in trying to agree with the contents of the covenant [it] is better than having new rules from law. The Dutch government, traditionally eager for consensus, has struck a number of such deals with Dutch industries - including packaging, metal, and tire - to reduce emissions and set up environmental management programs. The effort is based on the government's National Environmental Policy Plans - NMP and NMP Plus. Targets for emissions reduction by the chemical industry were provided by a government-funded environmental research institute.

  6. Inflammatory responses to infection: the Dutch contribution.

    PubMed

    Nolte, Martijn A; van der Meer, Jos W M

    2014-12-01

    At any given moment, our body is under attack by a large variety of pathogens, which aim to enter and use our body to propagate and disseminate. The extensive cellular and molecular complexity of our immune system enables us to efficiently eliminate invading pathogens or at least develop a condition in which propagation of the microorganism is reduced to a minimum. Yet, the evolutionary pressure on pathogens to circumvent our immune defense mechanisms is immense, which continuously leads to the development of novel pathogenic strains that challenge the health of mankind. Understanding this battle between pathogen and the immune system has been a fruitful area of immunological research over the last century and will continue to do so for many years. In this review, which has been written on the occasion of the 50th anniversary of the Dutch Society for Immunology, we provide an overview of the major contributions that Dutch immunologists and infection biologists have made in the last decades on the inflammatory response to viral, bacterial, fungal or parasitic infections. We focus on those studies that have addressed both the host and the pathogen, as these are most interesting from an immunological point of view. Although it is not possible to completely cover this comprehensive research field, this review does provide an interesting overview of Dutch research on inflammatory responses to infection. PMID:25455597

  7. Tolerance at arm's length: the Dutch experience.

    PubMed

    Schuijer, J

    1990-01-01

    With respect to pedophilia and the age of consent, the Netherlands warrants special attention. Although pedophilia is not as widely accepted in the Netherlands as sometimes is supposed, developments in the judicial practice showed a growing reservedness. These developments are a spin-off of related developments in Dutch society. The tolerance in the Dutch society has roots that go far back in history and is also a consequence of the way this society is structured. The social changes of the sixties and seventies resulted in a "tolerance at arm's length" for pedophiles, which proved to be deceptive when the Dutch government proposed to lower the age of consent in 1985. It resulted in a vehement public outcry. The prevailing sex laws have been the prime target of protagonists of pedophile emancipation. Around 1960, organized as a group, they started to undertake several activities. In the course of their existence, they came to redefine the issue of pedophilia as one of youth emancipation. PMID:2086632

  8. Performance of Dutch Children on the Bayley III: A Comparison Study of US and Dutch Norms

    PubMed Central

    Steenis, Leonie J. P.; Verhoeven, Marjolein; Hessen, Dave J.; van Baar, Anneloes L.

    2015-01-01

    Background The Bayley Scales of Infant and Toddler Development-third edition (Bayley-III) are frequently used to assess early child development worldwide. However, the original standardization only included US children, and it is still unclear whether or not these norms are adequate for use in other populations. Recently, norms for the Dutch version of the Bayley-III (The Bayley-III-NL) were made. Scores based on Dutch and US norms were compared to study the need for population-specific norms. Methods Scaled scores based on Dutch and US norms were compared for 1912 children between 14 days and 42 months 14 days. Next, the proportions of children scoring < 1-SD and < -2 SD based on the two norms were compared, to identify over- or under-referral for developmental delay resulting from non-population-based norms. Results Scaled scores based on Dutch norms fluctuated around values based on US norms on all subtests. The extent of the deviations differed across ages and subtests. Differences in means were significant across all five subtests (p < .01) with small to large effect sizes (ηp2) ranging from .03 to .26). Using the US instead of Dutch norms resulted in over-referral regarding gross motor skills, and under-referral regarding cognitive, receptive communication, expressive communication, and fine motor skills. Conclusions The Dutch norms differ from the US norms for all subtests and these differences are clinically relevant. Population specific norms are needed to identify children with low scores for referral and intervention, and to facilitate international comparisons of population data. PMID:26267907

  9. Dynamics of Sun5 Localization during Spermatogenesis in Wild Type and Dpy19l2 Knock-Out Mice Indicates That Sun5 Is Not Involved in Acrosome Attachment to the Nuclear Envelope

    PubMed Central

    Yassine, Sandra; Escoffier, Jessica; Nahed, Roland Abi; Pierre, Virginie; Karaouzene, Thomas; Ray, Pierre F.; Arnoult, Christophe

    2015-01-01

    The acrosome is an organelle that is central to sperm physiology and a defective acrosome biogenesis leads to globozoospermia, a severe male infertility. The identification of the actors involved in acrosome biogenesis is therefore particularly important to decipher the molecular pathogeny of globozoospermia. We recently showed that a defect in the DPY19L2 gene is present in more than 70% of globozoospermic men and demonstrated that Dpy19l2, located in the inner nuclear membrane, is the first protein involved in the attachment of the acrosome to the nuclear envelope (NE). SUN proteins serve to link the nuclear envelope to the cytoskeleton and are therefore good candidates to participate in acrosome-nucleus attachment, potentially by interacting with DPY19L2. In order to characterize new actors of acrosomal attachment, we focused on Sun5 (also called Spag4l), which is highly expressed in male germ cells, and investigated its localization during spermatogenesis. Using immunohistochemistry and Western blot experiments in mice, we showed that Sun5 transits through different cellular compartments during meiosis. In pachytene spermatocytes, it is located in a membranous compartment different to the reticulum. In round spermatids, it progresses to the Golgi and the NE before to be located to the tail/head junction in epididymal sperm. Interestingly, we demonstrate that Sun5 is not, as initially reported, facing the acrosome but is in fact excluded from this zone. Moreover, we show that in Dpy19l2 KO spermatids, upon the detachment of the acrosome, Sun5 relocalizes to the totality of the NE suggesting that the acrosome attachment excludes Sun5 from the NE facing the acrosome. Finally, Western-blot experiments demonstrate that Sun5 is glycosylated. Overall, our work, associated with other publications, strongly suggests that the attachment of the acrosome to the nucleus does not likely depend on the formation of SUN complexes. PMID:25775128

  10. Verb inflection in Monolingual Dutch and Sequential Bilingual Turkish-Dutch Children with and without SLI

    ERIC Educational Resources Information Center

    Blom, Elma; De Jong, Jan; Orgassa, Antje; Baker, Anne; Weerman, Fred

    2013-01-01

    Both children with specific language impairment (SLI) and children who acquire a second language (L2) make errors with verb inflection. This overlap between SLI and L2 raises the question if verb inflection can discriminate between L2 children with and without SLI. In this study we addressed this question for Dutch. The secondary goal of the study…

  11. Piezoelectric Polymers

    NASA Technical Reports Server (NTRS)

    Harrison, J. S.; Ounaies, Z.; Bushnell, Dennis M. (Technical Monitor)

    2001-01-01

    The purpose of this review is to detail the current theoretical understanding of the origin of piezoelectric and ferroelectric phenomena in polymers; to present the state-of-the-art in piezoelectric polymers and emerging material systems that exhibit promising properties; and to discuss key characterization methods, fundamental modeling approaches, and applications of piezoelectric polymers. Piezoelectric polymers have been known to exist for more than forty years, but in recent years they have gained notoriety as a valuable class of smart materials.

  12. Challenges to prevention in Dutch general practice.

    PubMed

    Drenthen, T

    1997-06-01

    In the Netherlands the general practitioner (GP) plays an important role in prevention. Every Dutch citizen has to be registered with one GP and GPs know their patients well. Face-to-face contact is a relatively effective means of influencing behavior; if preventive advice is related to a patient's state of health, compliance may be stimulated. However, Dutch GPs have shown reluctance toward preventive work. Curing rather than preventing disease is emphasized in medical school. Many GPs doubt that they are entitled to interfere with a patients' lifestyle unless asked. Some GPs are aware of their limited knowledge of nutrition. Preventive work requires some reorganization of medical practice and can lead to an increased workload, without financial compensation. Then there is the "prevention paradox": preventive actions that have a demonstrable effect on the whole population bring only small benefits for individuals. Since 1989 the Dutch College of General Practitioners has published 60 standards for general practice. Several of these include advice on lifestyle and diet, eg, for non-insulin-dependent diabetes mellitus, hypertension, hypercholesterolemia, peptic ulcer, and heart failure. Prevention work in general practice must use only interventions proved to be effective and they must be feasible in the context of general practice. A trial collaboration of 118 GPs and 5 public health authorities between 1988 and 1990 for screening and lifestyle management of hypertension was a limited success. It brought to light the practical problems of this type of work in general practice. Present government priorities for GP-public health collaboration are influenza vaccination and cervical screening. PMID:9174499

  13. Dutch Elementary School Children's Attribution of Meaning to Written Pseudowords

    ERIC Educational Resources Information Center

    Tellings, Agnes; Bouts, Lex

    2011-01-01

    Grade two through six elementary school Dutch children were asked to perform a lexical decision task including 90 pseudowords constructed by changing one or two letters in a Dutch word. Subsequently, the children were asked about the meaning of pseudowords they had not crossed out and that they, apparently, had considered to be words. Multiple…

  14. Neural Correlates of Dutch Verb Second in Speech Production

    ERIC Educational Resources Information Center

    den Ouden, Dirk-Bart; Hoogduin, Hans; Stowe, Laurie A.; Bastiaanse, Roelien

    2008-01-01

    Dutch speakers with agrammatic Broca's aphasia are known to have problems with the production of finite verbs in main clauses. This performance pattern has been accounted for in terms of the specific syntactic complexity of the Dutch main clause structure, which requires an extra syntactic operation (Verb Second), relative to the basic…

  15. The Dutch Are Missing in the American Curriculum

    ERIC Educational Resources Information Center

    Claunch, Ann

    2009-01-01

    The Dutch are missing in any U.S. history textbook, in the content standards, and in the nationally endorsed curriculum. Outside of New York State history classes, there is almost no mention of the Dutch influence in early 17th-century America. Fleeting references to the Netherlands as a staging area for the Pilgrims' famous "Mayflower" voyage or…

  16. Units of Analysis in Reading Dutch Bisyllabic Pseudowords

    ERIC Educational Resources Information Center

    Verhoeven, Ludo; Schreuder, Robert; Baayen, Harald

    2003-01-01

    Two experiments were carried out to explore the units of analysis used by children to read Dutch bisyllabic pseudowords. Although Dutch orthography is highly regular, several deviations from a one-to-one correspondence occur. In polysyllabic words, the grapheme e may represent three different vowels: /e/, /e/, or [/schwa/]. In Experiment 1, Grade…

  17. Prefix Identification in the Reading of Dutch Bisyllabic Words

    ERIC Educational Resources Information Center

    Verhoeven, Ludo; Schreuder, Robert; Haarman, Vera

    2006-01-01

    Two experiments were conducted in order to explore the role of prefix identification in the reading of Dutch bisyllabic words. Although Dutch orthography is highly regular, several deviations from a one-to-one correspondence exist. A case in point is the grapheme E which can represent the vowels epsilon, e and oe in polysyllabic words. In…

  18. The Electrophysiological Manifestation of Dutch Verb Second Violations

    ERIC Educational Resources Information Center

    den Ouden, Dirk-Bart; Bastiaanse, Roelien

    2009-01-01

    We investigated the processing of violations of the verb position in Dutch, in a group of healthy subjects, by measuring event-related potentials (ERPs) through electroencephalography (EEG). In Dutch, the base position of the verb is clause final, but in matrix clauses, the finite verb is in second position, a construction known as "Verb Second".…

  19. Agrammatic Sentence Production: Is Verb Second Impaired in Dutch?

    ERIC Educational Resources Information Center

    Kok, Peter; Kolk, Herman; Haverkort, Marco

    2006-01-01

    This study investigates effects of verb movement in nine Dutch-speaking agrammatic aphasics. According to linguistic theory, in verb second languages such as Dutch and German, the verb remains in its clause-final base position in embedded clauses, whereas it moves to second position in main clauses. In recent linguistic accounts of agrammatic…

  20. Ecological compensation in Dutch highway planning.

    PubMed

    Cuperus, R; Bakermans, M M; De Haes, H A; Canters, K J

    2001-01-01

    The ecological compensation principle was introduced by the Dutch government in 1993. This principle is designed to enhance the input of nature conservation interests in decision-making on large-scale development projects and to counterbalance the ecological impacts of such developments when implemented. This article evaluates the application of the Dutch compensation principle in highway planning. Six current highway projects reveal consistent implementation of this principle, although provincial policies on compensation and a national method for identifying compensation measures are still under development. As the planning process has not yet been completed for all the projects, no general conclusions can be drawn on the impact of the compensation principle on highway decision-making. Nevertheless, several examples show that the principle stimulates project initiators to develop alternative routes or route sections in order to avoid or reduce ecological impacts and the need for coherent compensation measures. If the compensation principle is to be properly implemented in the context of highway planning, particular attention should be paid to the following aspects: (1) sequential assessment of overall project legitimacy and the necessity of intersecting protected areas and compensation measures. (2) the initiator's attempts to avoid and mitigate ecological impacts in developing alternative routes prior to compensation for impacts, and (3) the role of uncertain ecological impacts in identifying compensation measures, especially those concerning habitat isolation. PMID:11083910

  1. Cancer incidence in Dutch Balkan veterans.

    PubMed

    Bogers, Rik P; van Leeuwen, Flora E; Grievink, Linda; Schouten, Leo J; Kiemeney, Lambertus A L M; Schram-Bijkerk, Dieneke

    2013-10-01

    Suspicion has been raised about an increased cancer risk among Balkan veterans because of alleged exposure to depleted uranium. The authors conducted a historical cohort study to examine cancer incidence among Dutch Balkan veterans. Male military personnel (n=18,175, median follow-up 11 years) of the Army and Military Police who had been deployed to the Balkan region (1993-2001) was compared with their peers not deployed to the Balkans (n=135,355, median follow-up 15 years) and with the general Dutch population of comparable age and sex. The incidence of all cancers and 4 main cancer subgroups was studied in the period 1993-2008. The cancer incidence rate among Balkan deployed military men was 17% lower than among non-Balkan deployed military men (hazard ratio 0.83 (95% confidence interval 0.69, 1.00)). For the 4 main cancer subgroups, hazard ratios were statistically non-significantly below 1. Also compared to the general population cancer rates were lower in Balkan deployed personnel (standardised incidence rate ratio (SIR) 0.85 (0.73, 0.99). The SIR for leukaemia was 0.63 (0.20, 1.46). The authors conclude that earlier suggestions of increased cancer risks among veterans are not supported by empirical data. The lower risk of cancer might be explained by the 'healthy warrior effect'. PMID:23707157

  2. Implementing prospective budgeting for Dutch sickness funds.

    PubMed

    Okma, K G; Poelert, J D

    2001-06-01

    Most if not all social policies entail redistribution of scarce public resources from central government to regional and local authorities, to individual citizens or non-government agencies. Governments use a wide variety of instruments to allocate public funds, including direct state provision of subsidies and goods and services, setting budgets at different levels, and regulation of social insurance schemes. Most industrialised countries have developed budget models based on implicit or explicit allocation criteria. Governments usually start by determining global budgets for an entire category of public spending and then specifying the amounts allocated for categories of spending, and next, the budgets for individual agencies. Within such a 'cascading' model, the lower level budgets may be more controversial than the global budgets, as they directly affect the amounts available to individual actors in the system, e.g. hospitals or health insurance agencies. Setting budgets not only shifts decision-making authority but also financial risks from the central government to decentralised actors. The introduction of the prospective budgeting model for the Dutch sickness funds illustrates why determining budgets is not merely a matter of choosing objective allocation criteria, but also, of interaction between state and stakeholders. In the typical Dutch neocorporatist policy arena, where organised interests share responsibilities with government for the shaping and implementation of social policies, the health insurance agencies actively participated in the development of the budget model. PMID:11420806

  3. Dutch Cycling: Quantifying the Health and Related Economic Benefits.

    PubMed

    Fishman, Elliot; Schepers, Paul; Kamphuis, Carlijn Barbara Maria

    2015-08-01

    The Netherlands is well known for their high bicycle use. We used the Health Economic Assessment Tool and life table calculations to quantify the population-level health benefits from Dutch cycling levels. Cycling prevents about 6500 deaths each year, and Dutch people have half-a-year-longer life expectancy because of cycling. These health benefits correspond to more than 3% of the Dutch gross domestic product. Our study confirmed that investments in bicycle-promoting policies (e.g., improved bicycle infrastructure and facilities) will likely yield a high cost-benefit ratio in the long term. PMID:26066942

  4. Polymer Electrolytes

    NASA Astrophysics Data System (ADS)

    Hallinan, Daniel T.; Balsara, Nitash P.

    2013-07-01

    This review article covers applications in which polymer electrolytes are used: lithium batteries, fuel cells, and water desalination. The ideas of electrochemical potential, salt activity, and ion transport are presented in the context of these applications. Potential is defined, and we show how a cell potential measurement can be used to ascertain salt activity. The transport parameters needed to fully specify a binary electrolyte (salt + solvent) are presented. We define five fundamentally different types of homogeneous electrolytes: type I (classical liquid electrolytes), type II (gel electrolytes), type III (dry polymer electrolytes), type IV (dry single-ion-conducting polymer electrolytes), and type V (solvated single-ion-conducting polymer electrolytes). Typical values of transport parameters are provided for all types of electrolytes. Comparison among the values provides insight into the transport mechanisms occurring in polymer electrolytes. It is desirable to decouple the mechanical properties of polymer electrolyte membranes from the ionic conductivity. One way to accomplish this is through the development of microphase-separated polymers, wherein one of the microphases conducts ions while the other enhances the mechanical rigidity of the heterogeneous polymer electrolyte. We cover all three types of conducting polymer electrolyte phases (types III, IV, and V). We present a simple framework that relates the transport parameters of heterogeneous electrolytes to homogeneous analogs. We conclude by discussing electrochemical stability of electrolytes and the effects of water contamination because of their relevance to applications such as lithium ion batteries.

  5. Star Polymers.

    PubMed

    Ren, Jing M; McKenzie, Thomas G; Fu, Qiang; Wong, Edgar H H; Xu, Jiangtao; An, Zesheng; Shanmugam, Sivaprakash; Davis, Thomas P; Boyer, Cyrille; Qiao, Greg G

    2016-06-22

    Recent advances in controlled/living polymerization techniques and highly efficient coupling chemistries have enabled the facile synthesis of complex polymer architectures with controlled dimensions and functionality. As an example, star polymers consist of many linear polymers fused at a central point with a large number of chain end functionalities. Owing to this exclusive structure, star polymers exhibit some remarkable characteristics and properties unattainable by simple linear polymers. Hence, they constitute a unique class of technologically important nanomaterials that have been utilized or are currently under audition for many applications in life sciences and nanotechnologies. This article first provides a comprehensive summary of synthetic strategies towards star polymers, then reviews the latest developments in the synthesis and characterization methods of star macromolecules, and lastly outlines emerging applications and current commercial use of star-shaped polymers. The aim of this work is to promote star polymer research, generate new avenues of scientific investigation, and provide contemporary perspectives on chemical innovation that may expedite the commercialization of new star nanomaterials. We envision in the not-too-distant future star polymers will play an increasingly important role in materials science and nanotechnology in both academic and industrial settings. PMID:27299693

  6. Polymer Chemistry

    NASA Technical Reports Server (NTRS)

    Williams, Martha; Roberson, Luke; Caraccio, Anne

    2010-01-01

    This viewgraph presentation describes new technologies in polymer and material chemistry that benefits NASA programs and missions. The topics include: 1) What are Polymers?; 2) History of Polymer Chemistry; 3) Composites/Materials Development at KSC; 4) Why Wiring; 5) Next Generation Wiring Materials; 6) Wire System Materials and Integration; 7) Self-Healing Wire Repair; 8) Smart Wiring Summary; 9) Fire and Polymers; 10) Aerogel Technology; 11) Aerogel Composites; 12) Aerogels for Oil Remediation; 13) KSC's Solution; 14) Chemochromic Hydrogen Sensors; 15) STS-130 and 131 Operations; 16) HyperPigment; 17) Antimicrobial Materials; 18) Conductive Inks Formulations for Multiple Applications; and 19) Testing and Processing Equipment.

  7. Development of a Dutch Drainpipe exposure scenario

    NASA Astrophysics Data System (ADS)

    Tiktak, Aaldrik; Boesten, Jos; van der Linden, Ton

    2010-05-01

    In the new Dutch pesticide authorisation procedure, the leaching of pesticides to surface waters will be evaluated. The 90th percentile of the peak concentrations in all Dutch ditches will be used for the exposure assessment of aquatic organisms The peak concentration in surface waters is primarily affected by fast transfer routes (amongst others by macropores). For this reason, we developed a macropore version of the pesticide leaching model PEARL. The macropore version of PEARL describes transport of pesticides through the soil matrix and through two preferential flow domains, i.e. a bypass domain and an internal catchment domain. The drainpipe exposure assessment will be done for a single field site. We selected the Andelst field experiment (Scorza Júnior et al., 2004) for this purpose, because at this site sufficient data is available to parameterise and test the model. To assess the effect of weather variability on drainpipe concentration, the model is run for a 20-years period. Hydrological boundary conditions for the 20-years period were taken from nearby weather stations and ground water observation wells. Application of PEARL to this field site showed that the model adequately describes the peak concentration and the later decline of the concentration for two different pesticides. The exposure assessment at the Andelst field site results in 20 annual peak concentrations, that need to be compared with the 90th percentile of the peak concentration in all Dutch ditches, so we performed simulations with a spatially-distributed version of PEARL. This assessment resulted in 20 times n concentrations, with n the number of locations. A contour diagram was used to assess which weather year corresponds with the 90th percentile of all 20 times n peak concentrations. The X-coordinate in the contour diagram corresponds with the percentile of the cumulative distribution of the predicted concentrations due to spatial variability that is obtained for a median weather

  8. Material efficiency in Dutch packaging policy.

    PubMed

    Worrell, Ernst; van Sluisveld, Mariësse A E

    2013-03-13

    Packaging materials are one of the largest contributors to municipal solid waste generation. In this paper, we evaluate the material impacts of packaging policy in The Netherlands, focusing on the role of material efficiency (or waste prevention). Since 1991, five different policies have been implemented to reduce the environmental impact of packaging. The analysis shows that Dutch packaging policies helped to reduce the total packaging volume until 1999. After 2000, packaging consumption increased more rapidly than the baseline, suggesting that policy measures were not effective. Generally, we see limited attention to material efficiency to reduce packaging material use. For this purpose, we tried to gain more insight in recent activities on material efficiency, by building a database of packaging prevention initiatives. We identified 131 alterations to packaging implemented in the period 2005-2010, of which weight reduction was the predominant approach. More appropriate packaging policy is needed to increase the effectiveness of policies, with special attention to material efficiency. PMID:23359741

  9. Dutch refinery nears completion of major renovation

    SciTech Connect

    Rhodes, A.K.

    1997-03-17

    Shell Nederland Raffinaderij B.V. has completed construction of a major upgrade at its refinery in Pernis, The Netherlands. The project, called PER+, centers around the addition of Shell Gasification Hydrogen Process (SGHP) and hydrocracking units. The expansion will increase the complexity of Shell`s Dutch refinery and enable it to convert low-value streams to useful products such as cleaner-burning transportation fuels, hydrogen, and electricity. PER+ is a prime example of the kind of innovative planning necessary for European refineries to stay competitive in a tough market. The project reached mechanical completion early this year, and is scheduled to start up in May. The paper describes the refinery, project objectives, process options, the SGHP process, soot ash removal, syngas treatment, power and hydrogen production, environmental issues, and construction.

  10. Inertial properties of Dutch Warmblood horses.

    PubMed

    Buchner, H H; Savelberg, H H; Schamhardt, H C; Barneveld, A

    1997-06-01

    The complete set of three-dimensional inertial properties (mass, density, centre of mass, inertial tensor) was determined in 26 segments of six Dutch Warmblood horses. The measurements were performed with frozen segments similar to the procedure described by Lephart (1984, J. Biomechanics 17, 537-543). Based on these data linear regression models were developed for the estimation of inertial properties in living horses. The reproducibility of the dissection procedure was found to range between 2 and 9%. Both mean values and regression models are presented for all parameters. The mean standard error of estimation was 8% for the segment mass, 3% of the segment reference length for the position of the centre of mass, and 17% for the moments of inertia. PMID:9165402

  11. The art of governance of Dutch hospitals.

    PubMed

    Hoek, H

    1999-01-01

    Hospitals in The Netherlands are governed by two boards: The Board of Directors, the legal representative of the hospital, responsible for strategic and operational business activities; and the Supervisory Board, made up of co-opted volunteers and responsible for checking and approving of the major decisions of the Board of Directors. The question which arises is whether the system of governance is able to function appropriately and guarantee enough concern about general health problems, moral and ethical questions and the interest of the patients. This paper investigate the successes and shortfalls of such a system of governance in Dutch hospitals. The results and conclusions determine that although copied from the corporate governance model, it does not function well in an environment where the influence of patients and the inhabitants of the region are of great importance and shareholders do not exist. PMID:10977190

  12. The Dutch school of malaria research.

    PubMed

    Verhave, J P

    1987-01-01

    An epidemic of tertian malaria in some coastal areas of The Netherlands resulted in the setting up of official measures in 1920. A scientific and a propaganda commission were charged with control. Efforts were made to reduce mosquito populations by adult and larval spraying. After the discovery that infected mosquitoes were to be found only inside houses, control operations were focussed against adult mosquitoes. Some later discoveries resulted in a more effective control. a) Spraying ditches with Paris green did not prevent adult mosquitoes from entering the control area. b) Anopheles maculipennis turned out to be a complex of species, with A. atroparvus as the vector. The latter preferred brackish water and did not go into full hibernation. The closing of the Zuyder Sea and the expected desalinization gave hope for less suitable conditions for the vector. c) Plasmodium vivax normally had an incubation period of 8 months. d) Pyrethrum was an effective but short-lasting insecticide. e) Healthy parasite carriers could infect mosquitoes. This knowledge was applied through an extensive system of investigation, including spleen examination of schoolchildren. Suspected houses were sprayed bimonthly from August to November, during which period infected mosquitoes were likely to be present. This system worked extremely well, and during the next epidemic from 1943 to 1947 the thus treated towns remained virtually free of malaria! DDT became available and was either sprayed in suspected houses as before, or through wide-spread coverage of all houses. The epidemic subsided whatever method employed and not only due to the use of DDT. The number of cases even went down to the point of no return and the last case of Dutch malaria was recorded in 1959. The wealth of experience on house-spray control, parasite and mosquito biology and experimental malaria of the Dutch malariologists has had its impact on the international bodies engaged in the battle against malaria. PMID:3334084

  13. Predicting naming latencies for action pictures: Dutch norms.

    PubMed

    Shao, Zeshu; Roelofs, Ardi; Meyer, Antje S

    2014-03-01

    The present study provides Dutch norms for age of acquisition, familiarity, imageability, image agreement, visual complexity, word frequency, and word length (in syllables) for 124 line drawings of actions. Ratings were obtained from 117 Dutch participants. Word frequency was determined on the basis of the SUBTLEX-NL corpus (Keuleers, Brysbaert, & New, Behavior Research Methods, 42, 643-650, 2010). For 104 of the pictures, naming latencies and name agreement were determined in a separate naming experiment with 74 native speakers of Dutch. The Dutch norms closely corresponded to the norms for British English. Multiple regression analysis showed that age of acquisition, imageability, image agreement, visual complexity, and name agreement were significant predictors of naming latencies, whereas word frequency and word length were not. Combined with the results of a principal-component analysis, these findings suggest that variables influencing the processes of conceptual preparation and lexical selection affect latencies more strongly than do variables influencing word-form encoding. PMID:23771428

  14. INTERIOR VIEW OF THE KITCHEN. SHOWING THE DUTCH DOOR TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF THE KITCHEN. SHOWING THE DUTCH DOOR TO THE SERVICE PORCH. PANTRY AND DOOR TO THE DINING ROOM ARE TO THE LEFT. VIEW FACING NORTH. - Hickam Field, Officers' Housing Type K, 304 Sixth Street, Honolulu, Honolulu County, HI

  15. Interior view of addition pharmacy showing dutch door and security ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view of addition pharmacy showing dutch door and security ceiling grate, facing north. - Albrook Air Force Station, Dispensary, East side of Canfield Avenue, Balboa, Former Panama Canal Zone, CZ

  16. Interior view of dutch door, double doorway with operable transom, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view of dutch door, double doorway with operable transom, and typical single doorway with transom, facing south. - Marine Barracks, Panama Canal, Barracks Building, 100' North of Thatcher Highway, Balboa, Former Panama Canal Zone, CZ

  17. Polymer Informatics

    NASA Astrophysics Data System (ADS)

    Adams, Nico

    Polymers are arguably the most important set of materials in common use. The increasing adoption of both combinatorial as well as high-throughput approaches, coupled with an increasing amount of interdisciplinarity, has wrought tremendous change in the field of polymer science. Yet the informatics tools required to support and further enhance these changes are almost completely absent. In the first part of the chapter, a critical analysis of the challenges facing modern polymer informatics is provided. It is argued, that most of the problems facing the field today are rooted in the current scholarly communication process and the way in which chemists and polymer scientists handle and publish data. Furthermore, the chapter reviews existing modes of representing and communicating polymer information and discusses the impact, which the emergence of semantic technologies will have on the way in which scientific and polymer data is published and transmitted. In the second part, a review of the use of informatics tools for the prediction of polymer properties and in silico design of polymers is offered.

  18. Polymers & People

    ERIC Educational Resources Information Center

    Lentz, Linda; Robinson, Thomas; Martin, Elizabeth; Miller, Mary; Ashburn, Norma

    2004-01-01

    Each Tuesday during the fall of 2002, teams of high school students from three South Carolina counties conducted a four-hour polymer institute for their peers. In less than two months, over 300 students visited the Charleston County Public Library in Charleston, South Carolina, to explore DNA, nylon, rubber, gluep, and other polymers. Teams of…

  19. Persistent Identifiers for Dutch cultural heritage institutions

    NASA Astrophysics Data System (ADS)

    Ras, Marcel; Kruithof, Gijsbert

    2016-04-01

    Over the past years, more and more collections belonging to archives, libraries, media, museums, and knowledge institutes are being digitised and made available online. These are exciting times for ALM institutions. They are realising that, in the information society, their collections are goldmines. Unfortunately most heritage institutions in the Netherlands do not yet meet the basic preconditions for long-term availability of their collections. The digital objects often have no long lasting fixed reference yet. URL's and web addresses change. Some digital objects that were referenced in Europeana and other portals can no longer be found. References in scientific articles have a very short life span, which is damaging for scholarly research. In 2015, the Dutch Digital Heritage Network (NDE) has started a two-year work program to co-ordinate existing initiatives in order to improve the (long-term) accessibility of the Dutch digital heritage for a wide range of users, anytime, anyplace. The Digital Heritage Network is a partnership established on the initiative of the Ministry of Education, Culture and Science. The members of the NDE are large, national institutions that strive to professionally preserve and manage digital data, e.g. the National Library, The Netherlands Institute for Sound and Vision, the Netherlands Cultural Heritage Agency, the Royal Netherlands Academy of Arts and Sciences, the National Archive of the Netherlands and the DEN Foundation, and a growing number of associations and individuals both within and outside the heritage sector. By means of three work programmes the goals of the Network should be accomplished and improve the visibility, the usability and the sustainability of digital heritage. Each programme contains of a set of projects. Within the sustainability program a project on creating a model for persistent identifiers is taking place. The main goals of the project are (1) raise awareness among cultural heritage institutions on the

  20. Measurement of sigma Lambda b0/sigma B0 x B(Lambda b0-->Lambda c+pi-)/B(B0-->D+pi-) in pp collisions at square root s=1.96 TeV.

    PubMed

    Abulencia, A; Adelman, J; Affolder, T; Akimoto, T; Albrow, M G; Ambrose, D; Amerio, S; Amidei, D; Anastassov, A; Anikeev, K; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Arguin, J-F; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Bedeschi, F; Behari, S; Belforte, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Budroni, S; Burkett, K; Busetto, G; Bussey, P; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carillo, S; Carlsmith, D; Carosi, R; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, I; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciljak, M; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Coca, M; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Cyr, D; DaRonco, S; D'Auria, S; Davies, T; D'Onofrio, M; Dagenhart, D; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; Dell'Orso, M; Delli Paoli, F; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; DiTuro, P; Dörr, C; Donati, S; Donega, M; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, I; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Field, R; Flanagan, G; Foland, A; Forrester, S; Foster, G W; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garcia, J E; Garberson, F; Garfinkel, A F; Gay, C; Gerberich, H; Gerdes, D; Giagu, S; Giannetti, P; Gibson, A; Gibson, K; Gimmell, J L; Ginsburg, C; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Goldstein, J; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Griffiths, M; Grinstein, S; Grosso-Pilcher, C; Group, R C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Hamilton, A; Han, B-Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hauser, J; Heijboer, A; Heinemann, B; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Holloway, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ishizawa, Y; Ivanov, A; Iyutin, B; James, E; Jang, D; Jayatilaka, B; Jeans, D; Jensen, H; Jeon, E J; Jindariani, S; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Karchin, P E; Kato, Y; Kemp, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kovalev, A; Kraan, A C; Kraus, J; Kravchenko, I; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; Le, Y; LeCompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Loverre, P; Lu, R-S; Lucchesi, D; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Manca, G; Margaroli, F; Marginean, R; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Maruyama, T; Mastrandrea, P; Masubuchi, T; Matsunaga, H; Mattson, M E; Mazini, R; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyamoto, A; Moed, S; Moggi, N; Mohr, B; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Nachtman, J; Nagano, A; Naganoma, J; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nigmanov, T; Nodulman, L; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagliarone, C; Palencia, E; Papadimitriou, V; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ranjan, N; Rappoccio, S; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Sabik, S; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Saltzberg, D; Sánchez, C; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savard, P; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyrla, A; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Sjolin, J; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; Staveris-Polykalas, A; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Takikawa, K; Tanaka, M; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tseng, J; Tsuchiya, R; Tsuno, S; Turini, N; Ukegawa, F; Unverhau, T; Uozumi, S; Usynin, D; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Veramendi, G; Veszpremi, V; Vidal, R; Vila, I; Vilar, R; Vine, T; Vollrath, I; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner, J; Wagner, W; Wallny, R; Wang, S M; Warburton, A; Waschke, S; Waters, D; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zhou, J; Zucchelli, S

    2007-03-23

    We present the first observation of the baryon decay Lambda b0-->Lambda c+pi- followed by Lambda c+-->pK-pi+ in 106 pb-1 pp collisions at square root s=1.96 TeV in the CDF experiment. In order to reduce systematic error, the measured rate for Lambda b0 decay is normalized to the kinematically similar meson decay B0-->D+pi- followed by D+-->pi+K-pi+. We report the ratio of production cross sections (sigma) times the ratio of branching fractions (B) for the momentum region integrated above pT>6 GeV/c and pseudorapidity range |eta|<1.3: sigma(pp-->Lambda b0X)/sigma(pp-->B0X)xB(Lambda b0-->Lambda c+pi-)/B(B0-->D+pi-)=0.82+/-0.08(stat)+/-0.11(syst)+/-0.22[B(Lambda c+-->pK-pi+)]. PMID:17501113

  1. [Dutch computer domestication, 1975-1990].

    PubMed

    Veraart, Frank

    2008-01-01

    A computer seems an indispensable tool among twenty-first century households. Computers however, did not come as manna from heaven. The domestication and appropriation of computers in Dutch households was a result of activities by various intermediary actors. Computers became household commodities only gradually. Technophile computer hobbyists imported the first computers into the Netherlands from the USA, and started small businesses from 1975 onwards. They developed a social network in which computer technology was made available for use by individuals. This network extended itself via shops, clubs, magazines, and other means of acquiring and exchanging computer hard- and software. Hobbyist culture established the software-copying habits of private computer users as well as their ambivalence to commercial software. They also made the computer into a game machine. Under the impulse of a national policy that aimed at transforming society into an 'Information Society', clubs and other actors extended their activities and tailored them to this new agenda. Hobby clubs presented themselves as consumer organizations and transformed into intermediary actors that filled the gap between suppliers and a growing group of users. They worked hard to give meaning to (proper) use of computers. A second impulse to the increasing use of computers in the household came from so-called 'private-PC' projects in the late 1980s. In these projects employers financially aided employees in purchasing their own private PCs'. The initially important intermediary actors such as hobby clubs lost control and the agenda for personal computers was shifted to interoperability with office equipment. IBM compatible PC's flooded the households. In the household the new equipment blended with the established uses, such as gaming. The copying habits together with the PC standard created a risky combination in which computer viruses could spread easily. New roles arose for intermediary actors in guiding

  2. Organometallic Polymers.

    ERIC Educational Resources Information Center

    Carraher, Charles E., Jr.

    1981-01-01

    Reactions utilized to incorporate a metal-containing moiety into a polymer chain (addition, condensation, and coordination) are considered, emphasizing that these reactions also apply to smaller molecules. (JN)

  3. Polymer flooding

    SciTech Connect

    Littmann, W.

    1988-01-01

    This book covers all aspects of polymer flooding, an enhanced oil recovery method using water soluble polymers to increase the viscosity of flood water, for the displacement of crude oil from porous reservoir rocks. Although this method is becoming increasingly important, there is very little literature available for the engineer wishing to embark on such a project. In the past, polymer flooding was mainly the subject of research. The results of this research are spread over a vast number of single publications, making it difficult for someone who has not kept up-to-date with developments during the last 10-15 years to judge the suitability of polymer flooding to a particular field case. This book tries to fill that gap. An indispensable book for reservoir engineers, production engineers and lab. technicians within the petroleum industry.

  4. Polymers All Around You!

    ERIC Educational Resources Information Center

    Gertz, Susan

    Background information on natural polymers, synthetic polymers, and the properties of polymers is presented as an introduction to this curriculum guide. Details are provided on the use of polymer products in consumer goods, polymer recycling, polymer densities, the making of a polymer such as GLUEP, polyvinyl alcohol, dissolving plastics, polymers…

  5. Leaf trait dissimilarities between Dutch elm hybrids with a contrasting tolerance to Dutch elm disease

    PubMed Central

    Ďurkovič, Jaroslav; Čaňová, Ingrid; Lagaňa, Rastislav; Kučerová, Veronika; Moravčík, Michal; Priwitzer, Tibor; Urban, Josef; Dvořák, Miloň; Krajňáková, Jana

    2013-01-01

    Background and Aims Previous studies have shown that Ophiostoma novo-ulmi, the causative agent of Dutch elm disease (DED), is able to colonize remote areas in infected plants of Ulmus such as the leaf midrib and secondary veins. The objective of this study was to compare the performances in leaf traits between two Dutch elm hybrids ‘Groeneveld’ and ‘Dodoens’ which possess a contrasting tolerance to DED. Trait linkages were also tested with leaf mass per area (LMA) and with the reduced Young's modulus of elasticity (MOE) as a result of structural, developmental or functional linkages. Methods Measurements and comparisons were made of leaf growth traits, primary xylem density components, gas exchange variables and chlorophyll a fluorescence yields between mature plants of ‘Groeneveld’ and ‘Dodoens’ grown under field conditions. A recently developed atomic force microscopy technique, PeakForce quantitative nanomechanical mapping, was used to reveal nanomechanical properties of the cell walls of tracheary elements such as MOE, adhesion and dissipation. Key Results ‘Dodoens’ had significantly higher values for LMA, leaf tissue thickness variables, tracheary element lumen area (A), relative hydraulic conductivity (RC), gas exchange variables and chlorophyll a fluorescence yields. ‘Groeneveld’ had stiffer cell walls of tracheary elements, and higher values for water-use efficiency and leaf water potential. Leaves with a large carbon and nutrient investment in LMA tended to have a greater leaf thickness and a higher net photosynthetic rate, but LMA was independent of RC. Significant linkages were also found between the MOE and some vascular traits such as RC, A and the number of tracheary elements per unit area. Conclusions Strong dissimilarities in leaf trait performances were observed between the examined Dutch elm hybrids. Both hybrids were clearly separated from each other in the multivariate leaf trait space. Leaf growth, vascular and gas

  6. [The first Dutch debate on anaesthesia in obstetrics].

    PubMed

    Bijker, Liselotte E

    2015-01-01

    After the publication of the Dutch medical guideline on pharmacological analgesia during childbirth in 2008, the question of whether pharmacological pain relief should be permissible during labour was hotly debated. This discussion has been going on since the second half of the 19th century when the introduction of ether and chloroform was extensively studied and described in Great Britain. This article looks back on the same debate in the Netherlands when inhalational anaesthetics were introduced into obstetrics. Study of historical journals and textbooks, originating in the Netherlands and elsewhere, and of historical medical literature on anaesthesia and obstetrics shows that the Dutch protagonists adopted more nuanced ideas on this issue than many of their foreign colleagues. This description of the first Dutch debate on anaesthesia in obstetrics shows that in fact the issues and arguments are timeless. PMID:25827148

  7. [Smoking behavior of Dutch family physicians in 1983-1988].

    PubMed

    Adriaanse, H; van Reek, J; Rabier, J R

    1990-08-01

    General practitioners' smoking behaviour in The Netherlands is described on the basis of survey data collected in the period 1983-1988. Until 1983 a large majority of the Dutch family physicians were smokers (1957: 82%, 1983: 56%). The smoking prevalence then was higher among physicians than among the male population. After 1983 a new development set in. Three inquiries showed that among Dutch physicians the smoking prevalence in 1988 was lower than that among the male general population (29 versus 37%). Dutch family physicians have stopped smoking to a larger extent than the physicians in any other EC-country (43% ex-smokers). Young entry-level doctors more and more tend to be never-smokers. PMID:2392168

  8. Nicolaes Tulp and the golden age of the Dutch Republic.

    PubMed

    Simpson, Donald

    2007-12-01

    In the seventeenth century, Holland and the allied provinces of the northern Netherlands won final independence from their Spanish overlords and formed a worldwide economic empire. Dutch ships dominated the seas from the Caribbean to Japan and reconnoitred the coasts of Australia and New Zealand. Dutch society was cosmopolitan and supported great painters, philosophers and scientists. In these astonishing years, the physician Nicolaes Tulp [1593-1674] practised medicine in Amsterdam and, in 1641, published a book of his medical observations. This book ran into many editions; the Cowlishaw collection contains one of the last, dated 1716. Tulp is best known as the chief figure in a famous painting by Rembrandt, but his book has been studied by medical historians as a source of early descriptions of cranial surgery, spina bifida, vesical calculi, beriberi and many other conditions. The book is also a mirror of Dutch society in a great period in European history. PMID:17973670

  9. Cultural Perspectives on Peer Conflicts in Multicultural Dutch Child Care Centres

    ERIC Educational Resources Information Center

    Rourou, Amina; Singer, Elly; Bekkema, Nienke; De Haan, Dorian

    2006-01-01

    In this paper we discuss a study of cultural perspectives on peer conflicts in multicultural child care centres. On the level of child behaviour we did not find differences between native Dutch. Moroccan-Dutch and Antillean-Dutch children with regard to occurrence, duration and actions to solve peer conflicts. On the level of mother' opinions…

  10. Word Order and Finiteness in Dutch and English Broca's and Wernicke's Aphasia

    ERIC Educational Resources Information Center

    Bastiaanse, Roelien; Edwards, Susan

    2004-01-01

    The effect of two linguistic factors in Broca's and Wernicke's aphasia was examined using Dutch and English subjects. Three tasks were used to test (1) the comprehension and (2) the construction of sentences, where verbs (in Dutch) and verb arguments (in Dutch and English) are in canonical versus non-canonical position; (3) the production of…

  11. Challenging Dutch Holocaust Education: Towards a Curriculum Based on Moral Choices and Empathetic Capacity

    ERIC Educational Resources Information Center

    Boersema, Jacob R.; Schimmel, Noam

    2008-01-01

    We analyse the way in which the Holocaust is taught in The Netherlands, with an emphasis on critically examining the content of secondary school textbooks used to teach Dutch students about the history of the Holocaust. We also interview Dutch educators, government officials and academics about the state of Dutch Holocaust education. Our findings…

  12. Antimocrobial Polymer

    DOEpatents

    McDonald, William F.; Huang, Zhi-Heng; Wright, Stacy C.

    2005-09-06

    A polymeric composition having antimicrobial properties and a process for rendering the surface of a substrate antimicrobial are disclosed. The composition comprises a crosslinked chemical combination of (i) a polymer having amino group-containing side chains along a backbone forming the polymer, (ii) an antimicrobial agent selected from quaternary ammonium compounds, gentian violet compounds, substituted or unsubstituted phenols, biguanide compounds, iodine compounds, and mixtures thereof, and (iii) a crosslinking agent containing functional groups capable of reacting with the amino groups. In one embodiment, the polymer is a polyamide formed from a maleic anhydride or maleic acid ester monomer and alkylamines thereby producing a polyamide having amino substituted alkyl chains on one side of the polyamide backbone; the crosslinking agent is a phosphine having the general formula (A)3P wherein A is hydroxyalkyl; and the antimicrobial agent is chlorhexidine, dimethylchlorophenol, cetyl pyridinium chloride, gentian violet, triclosan, thymol, iodine, and mixtures thereof.

  13. Antimicrobial Polymer

    DOEpatents

    McDonald, William F.; Wright, Stacy C.; Taylor, Andrew C.

    2004-09-28

    A polymeric composition having antimicrobial properties and a process for rendering the surface of a substrate antimicrobial are disclosed. The polymeric composition comprises a crosslinked chemical combination of (i) a polymer having amino group-containing side chains along a backbone forming the polymer, (ii) an antimicrobial agent selected from metals, metal alloys, metal salts, metal complexes and mixtures thereof, and (iii) a crosslinking agent containing functional groups capable of reacting with the amino groups. In one example embodiment, the polymer is a polyamide formed from a maleic anhydride or maleic acid ester monomer and alkylamines thereby producing a polyamide having amino substituted alkyl chains on one side of the polyamide backbone; the crosslinking agent is a phosphine having the general formula (A).sub.3 P wherein A is hydroxyalkyl; and the metallic antimicrobial agent is selected from chelated silver ions, silver metal, chelated copper ions, copper metal, chelated zinc ions, zinc metal and mixtures thereof.

  14. Polymer inflation

    NASA Astrophysics Data System (ADS)

    Hassan, Syed Moeez; Husain, Viqar; Seahra, Sanjeev S.

    2015-03-01

    We consider the semiclassical dynamics of a free massive scalar field in a homogeneous and isotropic cosmological spacetime. The scalar field is quantized using the polymer quantization method assuming that it is described by a Gaussian coherent state. For quadratic potentials, the semiclassical equations of motion yield a universe that has an early "polymer inflation" phase which is generic and almost exactly de Sitter, followed by an epoch of slow-roll inflation. We compute polymer corrections to the slow-roll formalism, and discuss the probability of inflation in this model using a physical Hamiltonian arising from time gauge fixing. We also show how in this model, it is possible to obtain a significant amount of slow-roll inflation from sub-Planckian initial data, hence circumventing some of the criticisms of standard scenarios. These results show the extent to which a quantum gravity motivated quantization method affects early universe dynamics.

  15. Productivity and quality of Dutch hospitals during system reform.

    PubMed

    van Ineveld, Martin; van Oostrum, Jeroen; Vermeulen, Rob; Steenhoek, Adri; van de Klundert, Joris

    2016-09-01

    This study addresses the productivity of Dutch hospitals since the start of the health systems reform in 2005. We consider DEA based measures, which include efficiency and quality for the complete set of Dutch hospitals and present cross-sectional and longitudinal analysis. In particular, we consider how hospital efficiency has developed. As the reform created an environment of regulated competition, we pay special attention to relative efficiency. Our results suggest that the differences in efficiency among hospitals have become larger. In the years 2009-2010, the number of hospitals identified as (close to) efficient by DEA analysis decreased. PMID:25774011

  16. Historical Notes on the Dutch and American-Dutch "schools" in Astronomy and Their Relations with Physics

    NASA Astrophysics Data System (ADS)

    van den Heuvel, Ed

    2006-04-01

    Dutch astronomy and physics experienced two "golden ages". The firstone covered the 17th century, culminating with Christiaan Huygens,inventor of the pendulum clock and the wave theory of light, anddiscoverer of Saturn's rings and largest satellite Titan. The secondone, which lasts till the present, started around 1880 withphysicists Lorentz, van der Waals, Zeeman and Kamerlingh Onnes andastronomer Kapteijn and his pupils De Sitter, van Rhijn, Oort andSchilt. Kapteijn, through his friendship with George Ellery Hale,initiated the strong connection between American and Dutch astronomy,which led to the rise of many Dutch-born astronomers to prominentpositions in the US, from Luyten, Bok, Brouwer, Schilt and Kuiperto Woltjer, Gehrels, and Beckers. The rise of the second "goldenage" appears to be closely related to drastic reforms in the Dutchhigh school and university systems in the last decades of the 19thcentury.

  17. Polymer solutions

    SciTech Connect

    Krawczyk, Gerhard Erich; Miller, Kevin Michael

    2011-07-26

    There is provided a method of making a polymer solution comprising polymerizing one or more monomer in a solvent, wherein said monomer comprises one or more ethylenically unsaturated monomer that is a multi-functional Michael donor, and wherein said solvent comprises 40% or more by weight, based on the weight of said solvent, one or more multi-functional Michael donor.

  18. Polymer Science.

    ERIC Educational Resources Information Center

    Frank, Curtis W.

    1979-01-01

    Described is a series of four graduate level courses in polymer science, offered or currently in preparation, at Stanford University. Course descriptions and a list of required and recommended texts are included. Detailed course outlines for two of the courses are presented. (BT)

  19. Functional polymers

    SciTech Connect

    Wegner, G.

    2000-01-01

    Improving the existing polymer materials and the designing of model polymers need fundamental insights into the structure and dynamics over a large range of length and time scales. Consequently, a host of quite different methods needs to be applied to gain insights into the molecular and supramolecular structures and interactions that determine the performance of these materials. Supramolecular structures derived from shape persistent (stiff) macromolecules are used as examples to demonstrate the correlation between chemical structure, order phenomena and performance in applications concerning advanced or developing technologies: organic light emitting diodes (OLEDs) and separator membranes in lithium based batteries and fuel cells. Polymers are also important as additives in the manufacture and the processing of other materials. The design of block copolymers to control the nucleation and growth of inorganic particles precipitating from aqueous solutions (mineralization) is discussed as well as the use of block copolymers to optimize the processing of ceramic pieces and objects. Finally, the modification of surfaces by polymers including aspects of biocompatibility is discussed. Some remarks concerning the importance of recent developments and advances in synthesis of macromolecular materials are also given.

  20. The Role of Dutch Government in Curriculum Design and Change.

    ERIC Educational Resources Information Center

    Huisman, Jeroen; Jenniskens, Ineke

    1994-01-01

    A discussion of Dutch higher education looks at whether a 1985 proposal for fundamental changes in the relationship between government and higher education institutions has been implemented with regard to curriculum design. It is concluded that, despite policy intentions for increased institutional autonomy, the government retains relatively tight…

  1. Acquisition of Publications from Asiatic Countries: Dutch Problems.

    ERIC Educational Resources Information Center

    Schiltman, Maria J.

    This presentation of the Dutch experience with the international exchange of publications focuses on the acquisition of publications from China and Indonesia to illustrate problems of availability. Lack of depository systems, restrictive export policies, inadequate national bibliographies, exorbitant commercial prices, and time consuming delivery…

  2. Smoking among Dutch Elementary Schoolchildren: Gender-Specific Predictors

    ERIC Educational Resources Information Center

    Ausems, M.; Mesters, I.; van Breukelen, G.; De Vries, H.

    2009-01-01

    Higher rates of smoking initiation and continuation by female compared with male adolescents, as found in many developed countries, may call for gender-specific prevention programs. Risk factors of smoking initiation and continuation were examined prospectively (1997-2002) among 3205 Dutch elementary schoolchildren (mean age 11.64) in an…

  3. The Speed of Obsolescence: Evidence from the Dutch Public Sector

    ERIC Educational Resources Information Center

    van Loo, Jasper B.

    2007-01-01

    HRD is extensively concerned with human capital investment, but only focuses on how skills and knowledge become obsolete to a limited extent. In this paper we look at the speed of obsolescence. Using data from a survey among Dutch public sector employees, we find that the yearly rate of skills obsolescence is 2.6%. Subsequent analyses show that…

  4. Developments and Issues in Dutch Adult Education Policy.

    ERIC Educational Resources Information Center

    Hake, Barry

    The three areas of educational activity recognized by the Dutch have developed historically into distinct and separate institutionalized sectors for educational provision for adults. These areas are knowledge-based, skill-based, and value-based. Each is the responsibility of a different governmental department and cabinet minister. Educational…

  5. "Modern" Governance and Codes of Conduct in Dutch Higher Education

    ERIC Educational Resources Information Center

    de Boer, Harry; Goedegebuure, Leo

    2007-01-01

    As one of the first countries in Europe to do so, The Netherlands moved towards a new relationship between the state and the higher education institutions in the mid-1980s. Autonomy, quality and accountability were key considerations in this move. In 2006 the Dutch government proposed another radical innovation in its approach to higher education…

  6. Contact Hours in Dutch and Vietnamese Higher Education: A Comparison

    ERIC Educational Resources Information Center

    Quyen, Do Thi Ngoc

    2009-01-01

    The number of contact hours, one of the important institutional context factors, was examined and compared between Dutch and Vietnamese higher education at institute and student levels in Psychology and Business and/or Economics specializations. The quantity of contact hours per credit point given by institutions was investigated in a number of…

  7. Gender Representation and Participation in Dutch Human Geography Departments. Symposium

    ERIC Educational Resources Information Center

    Fortuijn, Joos Droogleever

    2004-01-01

    Since the beginning of the 1970s the under-representation of women in geography has been questioned in several publications. Most articles refer to the situation in English-speaking countries. This paper examines the vertical and horizontal gender segregation in human geography departments in Dutch universities. In spite of several policy measures…

  8. Towards an "Americanization" of Dutch Drug Policy? [Revised].

    ERIC Educational Resources Information Center

    Marshall, Ineke Haen; And Others

    Historically, the Netherlands liberal approach to the problems related to drug use has been based on tolerance and a pragmatic concern for "harm reduction." Since the early 1980s, however, a shift has taken place in the direction of a tougher policy. This document describes: (1) the main features of the Dutch approach to the control of…

  9. Rhythm versus Analogy: Prosodic Form Variation in Dutch Compounds

    ERIC Educational Resources Information Center

    Neijt, Anneke; Schreuder, Robert

    2007-01-01

    Creating compound nouns is the most productive process of Dutch morphology, with an interesting pattern of form variation. For instance, "staat" "nation" simply combines with "kunde" "art" ("staatkunde" "political science, statesmanship"), but needs a linking element "s" or "en" to form staatsschuld "national debt" and "statenbond"…

  10. Attitudes toward Lesbians and Gays among American and Dutch Adolescents

    PubMed Central

    Collier, Kate L.; Horn, Stacey S.; Bos, Henny M. W.; Sandfort, Theo G. M.

    2014-01-01

    Attitudes toward lesbians and gays vary across national populations, and previous research has found relatively more accepting attitudes in the Netherlands as compared to the U.S. In this study, we compared beliefs about and attitudes toward lesbians and gays in samples of Dutch and American heterosexual adolescents, utilizing survey data from 1,080 American adolescents (mean age = 15.86 years) attending two schools and from 1,391 Dutch adolescents (mean age = 16.27 years) attending eight schools. Findings indicated the Dutch participants were more tolerant of lesbians and gays, after adjusting for the gender, age, and racial/ethnic minority status of the participants. However, between-country differences were attenuated by accounting for the beliefs about lesbians and gays that participants used to justify their attitudes. American participants were more likely to justify their attitudes using beliefs related to social norms and religious opposition, while the Dutch participants were more likely to justify their attitudes using beliefs related to individual rights and the biological/genetic basis of homosexuality. The results suggest that the relative importance of particular beliefs about lesbians and gays to attitudes at the group level may be context-dependent but also that certain beliefs are salient to attitudes across national contexts. PMID:24512056

  11. From Curacao: Papiamentu at Home, Dutch in School.

    ERIC Educational Resources Information Center

    Jones, Frances Faircloth

    1997-01-01

    Three major issues shape delivery of education in the Caribbean island of Curacao: the Dutch and Papiamentu languages of instruction, the two governmental layers, and scarcity of resources. Despite funding limitations, education is changing. The five-year general secondary education model and the six-year college preparatory program are being…

  12. Career Guidance and Student Success in Dutch Higher Vocational Education

    ERIC Educational Resources Information Center

    te Wierik, Mark L. J.; Beishuizen, Jos; van Os, Willem

    2015-01-01

    To enhance student success, a growing number of vocational education and training institutions in the Netherlands are nowadays implementing new career guidance practices in their competence-based approaches to learning. Based on individual-level data of undergraduate first-year full-time students from a Dutch university of applied sciences, this…

  13. Mentoring in Dutch Vocational Education: An Unfulfilled Promise

    ERIC Educational Resources Information Center

    Meijers, Frans

    2008-01-01

    Between 1998 and 2002 an estimated 250 mentoring programmes were started in Dutch secondary vocational education in order to decrease motivational problems and drop-out rates, especially among youngsters from ethnic minorities. Currently there are only two schools in secondary vocational education that include mentoring as part and parcel of their…

  14. The Dutch-Belgian beamline at the ESRF.

    PubMed

    Borsboom, M; Bras, W; Cerjak, I; Detollenaere, D; Glastra Van Loon, D; Goedtkindt, P; Konijnenburg, M; Lassing, P; Levine, Y K; Munneke, B; Oversluizen, M; Van Tol, R; Vlieg, E

    1998-05-01

    A brief description is given of the design principles and layout of the Dutch-Belgian beamline at the ESRF. This beamline optimizes the use of the available bending-magnet radiation fan by splitting the beam into two branches, each accommodating two experimental techniques. PMID:15263564

  15. Measurement of Tear Production in English Angora and Dutch Rabbits

    PubMed Central

    Rajaei, Seyed Mehdi; Rafiee, Siamak Mashhady; Ghaffari, Masoud Selk; Masouleh, Mohammad N; Jamshidian, Mahmoud

    2016-01-01

    The purpose of this study was to establish normal values for tear production tests in different breeds of domestic rabbits. Healthy adult rabbits (n = 60; 120 eyes) of 2 different breeds (English angora and Dutch; n = 15 of each sex and breed) were used in this study. Tear production was measured by using the 1-min Schirmer tear test (STT), phenol red thread test (PRTT), and endodontic absorbent paper point tear test (EAPTT). In addition, horizontal palpebral fissure length was evaluated as a measure of ocular adnexal dimensions. Tear production (mean ± 1 SD) in English angora rabbits was 5.4 ± 1.6 mm/min according to the STT, 25.0 ± 2.7 mm in 15 s for the PRTT, and 18.8 ± 2.1 mm/min by the EAPTT; in Dutch rabbits, these values were 4.6 ± 1.2 mm/min, 23.6 ± 2.3 mm in 15 s, and 16.9 ± 1.7 mm/min, respectively. Only the EAPTT revealed a significant difference in tear production between English Angora and Dutch rabbits. These results provide reference values for tear production in English Angora and Dutch rabbits according to 3 different quantitative tear film assessment methods. PMID:27025815

  16. OpenER, a Dutch Initiative in Open Educational Resources

    ERIC Educational Resources Information Center

    Schuwer, Robert; Mulder, Fred

    2009-01-01

    Over the period 2006-2008, the Dutch Open Universiteit Nederland conducted an experiment in which Open Educational Resources (OER) were offered in an effort to bridge the gap between informal and formal learning and to establish a new style of entry portal to higher education with no barriers at all. OpenER received considerable attention both in…

  17. Dutch Treat for U.S. Database Producers.

    ERIC Educational Resources Information Center

    Boumans, Jak

    1984-01-01

    Reports on investments in the United States (including database activities) by four Dutch publishing companies--Elsevier-NDU, VNU, Kluwer, Wolters Samsom Group. An analysis of the reasons behind these investments, the solidness of the companies, the approach to the U.S. information market, and the knowledge transfer to Europe are highlighted. (EJS)

  18. Citizenship Education and the Dutch National Identity Debate

    ERIC Educational Resources Information Center

    Doppen, Frans H.

    2010-01-01

    As a result of dramatic demographic changes during the last half century as well as a series of recent events surrounding prominent personas, the Dutch have been engaged in an intense debate about their national identity and how citizenship education can contribute to the integration of Muslim immigrants in particular. This article analyses the…

  19. Exploring EFL Literature Approaches in Dutch Secondary Education

    ERIC Educational Resources Information Center

    Bloemert, Jasmijn; Jansen, Ellen; van de Grift, Wim

    2016-01-01

    There is an increasing awareness that the inclusion of literature in foreign language (FL) curricula can be beneficial to language learners. Especially, the move towards integrated language and literature curricula is gaining ground. In this study we investigated the way English as a foreign language (EFL) is approached in Dutch secondary…

  20. Collaboration on ICT in Dutch Higher Education: The SURF Approach

    ERIC Educational Resources Information Center

    Boezerooy, Petra; Cordewener, Bas; Liebrand, Wim

    2007-01-01

    In "Thinking Ahead: A Vision of the Role of ICT in Education and Research in the Future, 2007-2010," the higher education institutions in the Netherlands agreed on future strategy. Under the direction of SURF, the Dutch national organization, a collaborative strategy for the application of information and communications technology (ICT) was…

  1. Alliances in the Dutch BeweegKuur Lifestyle Intervention

    ERIC Educational Resources Information Center

    den Hartog, Franciska; Wagemakers, Annemarie; Vaandrager, Lenneke; van Dijk, Marieke; Koelen, Maria A.

    2014-01-01

    Objective: BeweegKuur (Exercise Therapy) is a Dutch lifestyle programme in which participants are referred by a general practitioner (GP) to a lifestyle advisor. To support participants, regional and local alliances are established. The present study explored the successes and challenges associated with collaboration processes in local BeweegKuur…

  2. Two Profiles of the Dutch High Performing Employee

    ERIC Educational Resources Information Center

    de Waal, A. A.; Oudshoorn, Michella

    2015-01-01

    Purpose: The purpose of this study is to explore the profile of an ideal employee, to be more precise the behavioral characteristics of the Dutch high-performing employee (HPE). Organizational performance depends for a large part on the commitment of employees. Employees provide their knowledge, skills, experiences and creativity to the…

  3. Trends in Educational Disadvantage in Dutch Primary School

    ERIC Educational Resources Information Center

    Driessen, Geert; Merry, Michael S.

    2014-01-01

    The central question in this study is whether the language and math delays of the different socio-economic and ethnic minority groups targeted by Dutch educational disadvantage policy have diminished or not. Data are from the years 1995, 1999, 2003 and 2008. Information from a total of 90,000 pupils in Grades 2 and 8 was selected to represent the…

  4. Cognitive and Linguistic Constraints on Phoneme Isolation in Dutch Kindergartners

    ERIC Educational Resources Information Center

    de Graaff, Saskia; Hasselman, Fred; Bosman, Anna M. T.; Verhoeven, Ludo

    2008-01-01

    This study investigated whether task instructions affect sound-isolation performance. The effects of phoneme class and phoneme position were also assessed. Two hundred Dutch kindergartners were presented with a free-sound-isolation task and its constrained counterparts: an initial-, a middle-, and a final-sound-isolation task. All tasks contained…

  5. How Dutch employees experience freedom of learning for work

    NASA Astrophysics Data System (ADS)

    van Dellen, Theo; Heidekamp, Ina

    2015-12-01

    This article focuses on the perceived freedom of Dutch employees to embark on workplace learning in terms of whether they feel it is "voluntary" or "compulsory". The paper is based on the findings of a large international explorative survey carried out by the Workplace Learning (WPL) Research Network (RN2) of the Asia-Europe Meeting (ASEM) Lifelong Learning (LLL) Research Hub. The comparative study focused on employees' quest for "freedom of learning for work". This paper reports on the Dutch part of the research, the quantitative results of which seem to indicate that the freedom of learning for work is not as important to Dutch employees as might be expected. In a second phase, to investigate employees' experiences of work-related learning in more depth, the Dutch researchers added a follow-up qualitative study, involving one-on-one interviews. In order to triangulate the results of the quantitative and qualitative research phases, the authors then added a mixed-methods sequential explanatory analysis. They assessed the quality of the collected data in both distinct phases by identifying converging results, which are useful for refining our understanding of learning for work. The paper draws both on rich insights into workplace learning based on this research as well as on theoretical literature which refers to concepts like motivation, subjectivity, work identity and agency in connection with the quest for freedom of learning.

  6. Tensions in water management: Dutch tradition and European policy.

    PubMed

    Ravesteijn, W; Kroesen, O

    2007-01-01

    Present-day worldwide water problems require new management tools and sustainable system innovations. At Delft University of Technology research is being carried out into water resources and management development aimed at forming such tools and innovations, focused on Integrated River Basin Management (IRBM). One of the case-studies deals with Dutch water management and technology in the context of European IRBM in the form of the 2000 Water Frame Directive. The Netherlands experience many water problems and European IRBM could bring help by offering a framework for both international cooperation and technological innovations. To work as an adequate management tool European IRBM should be tailored to the Dutch water tradition, which recently culminated in Integrated Water Management. Both approaches are in some respects contradicting. Europe pursues, for example, centralized control; while the Dutch have their strongly water boards based decentralized administration. The tensions between both approaches require mutual adaptation, for which the concept of subsidiarity might offer points of departure. This paper describes the first results of the case-research into Dutch water management and technology in the context of Europe as well as the backgrounds and the set-up of the research as a whole. PMID:17851211

  7. A Collaborative Dialogue--Research in Dutch Language Education

    ERIC Educational Resources Information Center

    Van de Ven, Piet-Hein

    2007-01-01

    In order to address a perceived gap between academic knowledge and education, The Dutch National Advisory Board on Education has suggested that there is a need for more communication between research and practice. For me the gap is more than simply a matter of lack of communication, than a result of the model of Research, Development and Diffusion…

  8. Phonotactics and Morphophonology in Early Child Language: Evidence from Dutch

    ERIC Educational Resources Information Center

    Zamuner, Tania S.; Kerkhoff, Annemarie; Fikkert, Paula

    2012-01-01

    This research investigates children's knowledge of how surface pronunciations of lexical items vary according to their phonological and morphological context. Dutch-learning children aged 2.5 and 3.5 years were tested on voicing neutralization and morphophonological alternations. For instance, voicing does not alternate between the pair…

  9. SEAFOOD PROCESSING PERMITTING, ALASKA - UNALASKA BAY - DUTCH HARBOR

    EPA Science Inventory

    Unalaska Bay - Dutch Harbor was digitized from NOAA Marine Charts #16528, #16529, and #16530. Map details include water depth and land. This map was created for EPA Region 10 Water Division to evaluate NPDES permit sites and environmental quality. Visual illustration facilitates ...

  10. Sex Differences on the Dutch WAIS-III

    ERIC Educational Resources Information Center

    van der Sluis, Sophie; Posthuma, Danielle; Dolan, Conor V.; de Geus, Eco J. C.; Colom, Roberto; Boomsma, Dorret I.

    2006-01-01

    Using multi-group covariance and means structure analysis (MG-CMSA), this study investigated whether sex differences were present on the Dutch WAIS-III, and if so, whether these sex differences were attributable to differences in general intelligence ("g"). The sample consisted of 294 females and 228 males between 18 and 46 years old. Both first…

  11. Development of a Test of Spoken Dutch for Prospective Immigrants

    ERIC Educational Resources Information Center

    De Jong, John H. A. L.; Lennig, Matthew; Kerkhoff, Anne; Poelmans, Petra

    2009-01-01

    Based on a parliamentary vote with broad support, the Ministry of Justice of the Netherlands in December 2003 commissioned the development of an examination system to test the Dutch oral language skills of foreigners who want to immigrate permanently to the Netherlands for economic or family reasons. This assessment would take place in the country…

  12. Organisational Factors and Teachers' Professional Development in Dutch Secondary Schools

    ERIC Educational Resources Information Center

    Evers, Arnoud T.; van der Heijden, Beatrice I. J. M.; Kreijns, Karel; Gerrichhauzen, John T. G.

    2011-01-01

    Purpose: The purpose of this paper is to report on a study that investigates the relationship between organisational factors, Teachers' Professional Development (TPD) and occupational expertise. Design/methodology/approach: A survey was administered among 152 Dutch teachers in secondary education. Findings: Analysis of the data revealed that of…

  13. How Dutch Employees Experience Freedom of Learning for Work

    ERIC Educational Resources Information Center

    van Dellen, Theo; Heidekamp, Ina

    2015-01-01

    This article focuses on the perceived freedom of Dutch employees to embark on workplace learning in terms of whether they feel it is "voluntary" or "compulsory". The paper is based on the findings of a large international explorative survey carried out by the Workplace Learning (WPL) Research Network (RN2) of the Asia-Europe…

  14. Applying Dutch and US Versions of the BSID-II in Dutch Children Born Preterm Leads to Different Outcomes

    ERIC Educational Resources Information Center

    Westera, J. J.; Houtzager, B. A.; Overdiek, B.; van Wassenaer, A. G.

    2008-01-01

    The aim of the present study was to evaluate whether the application of Dutch versus US test procedures and norms of the Bayley Scales of Infant Development-2nd edition (BSID-II) leads to different developmental outcomes. The BSID-II was administered to 376 preterm infants (191 males, 185 females; mean gestational age 30wks [SD 2.7], mean…

  15. Advanced Polymer

    NASA Technical Reports Server (NTRS)

    1992-01-01

    In the mid-1980's, Langley developed a polyimide sulfone, combining desirable properties of two classes of polymers. Composites and other products made from polyimide sulfone can be used with solvents and corrosive fluids, are light weight, low cost and can be easily fabricated for a wide range of industrial uses. High Technology Systems, Inc. obtained a license for the polymer and was awarded a Small Business Innovation Research (SBIR) contract for development in a powder form. Although its principal use is as a matrix resin for composites, the material can also be used as a high temperature structural adhesive for aircraft structures and as a coating for protection from heat and radiation for electronic components.

  16. Phthalocyanine polymers

    NASA Technical Reports Server (NTRS)

    Achar, B. N.; Fohlen, G. M.; Parker, J. A. (Inventor)

    1985-01-01

    A method of forming 4,4',4'',4''' -tetraamino phthalocyanines involves reducing 4,4',4'',4''' -tetranitro phthalocyanines, polymerizing the metal tetraamino phthalocyanines with a tetracarboxylic dianhydride (preferably aromatic) or copolymerizing with a tetracarboxylic dianhydride and a diamine (preferably also aromatic) to produce amic acids which are then dehydrocyclized to imides. Thermally and oxidatively stable polymers result which form tough, flexible films, varnishes, adhesives, and fibers.

  17. Periodic Polymers

    NASA Astrophysics Data System (ADS)

    Thomas, Edwin

    2013-03-01

    Periodic polymers can be made by self assembly, directed self assembly and by photolithography. Such materials provide a versatile platform for 1, 2 and 3D periodic nano-micro scale composites with either dielectric or impedance contrast or both, and these can serve for example, as photonic and or phononic crystals for electromagnetic and elastic waves as well as mechanical frames/trusses. Compared to electromagnetic waves, elastic waves are both less complex (longitudinal modes in fluids) and more complex (longitudinal, transverse in-plane and transverse out-of-plane modes in solids). Engineering of the dispersion relation between wave frequency w and wave vector, k enables the opening of band gaps in the density of modes and detailed shaping of w(k). Band gaps can be opened by Bragg scattering, anti-crossing of bands and discrete shape resonances. Current interest is in our group focuses using design - modeling, fabrication and measurement of polymer-based periodic materials for applications as tunable optics and control of phonon flow. Several examples will be described including the design of structures for multispectral band gaps for elastic waves to alter the phonon density of states, the creation of block polymer and bicontinuous metal-carbon nanoframes for structures that are robust against ballistic projectiles and quasi-crystalline solid/fluid structures that can steer shock waves.

  18. Polymer Electronics: Power from Polymers

    SciTech Connect

    Venkataraman, D.; Russell, Thomas P.

    2012-06-19

    We review polymer-based electronics and photovoltaics to provide the reader with a sense of how the field has developed, where we stand at present, and what possibilities are looming in the future. Expertise in areas ranging from synthesis to morphology to device design was sought to achieve this end. While these reviews cannot be exhaustive, they do provide a snapshot of the field at present and give some sense of where the key impediments are.

  19. Combatting Electoral Traces: The Dutch Tempest Discussion and Beyond

    NASA Astrophysics Data System (ADS)

    Pieters, Wolter

    In the Dutch e-voting debate, the crucial issue leading to the abandonment of all electronic voting machines was compromising radiation, or tempest: it would be possible to eavesdrop on the choice of the voter by capturing the radiation from the machine. Other countries, however, do not seem to be bothered by this risk. In this paper, we use actor-network theory to analyse the socio-technical origins of the Dutch tempest issue in e-voting, and we introduce concepts for discussing its implications for e-voting beyond the Netherlands. We introduce the term electoral traces to denote any physical, digital or social evidence of a voter’s choices in an election. From this perspective, we provide a framework for risk classification as well as an overview of countermeasures against such traces.

  20. Predictors of photo naming: Dutch norms for 327 photos.

    PubMed

    Shao, Zeshu; Stiegert, Julia

    2016-06-01

    In the present study, we report naming latencies and norms for 327 photos of objects in Dutch. We provide norms for eight psycholinguistic variables: age of acquisition, familiarity, imageability, image agreement, objective and subjective visual complexity, word frequency, word length in syllables and letters, and name agreement. Furthermore, multiple regression analyses revealed that the significant predictors of photo-naming latencies were name agreement, word frequency, imageability, and image agreement. The naming latencies, norms, and stimuli are provided as supplemental materials. PMID:26122979

  1. [The Dutch emigration pattern around 1840 in the European perspective].

    PubMed

    Stokvis Prd

    1980-01-01

    "In 1850 and 1860 the Netherlands ranked eighth among twelve North-Western European nations that contributed to the transatlantic migration. The Dutch emigration pattern reflecting the agrarian crisis of the 1840's resembled the one of Hanover and Westphalia, be it that like in Scandinavia the ecclesiastical situation played a more important part. Besides the motivating forces, conditions such as information, organization, public and official reactions, and transportation are reviewed." (SUMMARY IN ENG) PMID:12311282

  2. High fatigue scores among older Dutch nurse anesthetists.

    PubMed

    Meeusen, Vera; Hoekman, Jaap; van Zundert, André

    2014-06-01

    In The Netherlands, hospital care production pressure recently increased substantially, while the number of nurse anesthetists available did not match this rise. The longtime existing norm of no night shifts for nurses beyond the age of 55 years was increased to age 57 to meet the demand for more nurse anesthetists. In this pilot study, we aimed to determine the level of fatigue and its correlation with demographic items among this category of employees. A validated questionnaire was distributed to all Dutch nurse anesthetists above 50 years of age working in Dutch hospitals, which asked for their level of fatigue. The Checklist Individual Strength Questionnaire was used to measure fatigue. Overall, 105 of 115 potential participants completed the questionnaire (response rate, 91%). The mean scores (+/- standard deviation) were as follows: total fatigue, 81.3 +/- 8.3; subjective fatigue, 31.4 +/- 3.2; physical activity, 13.1 +/- 2.2; motivation, 16.8 +/- 2.6; and concentration, 20.0 +/- 3.8. No correlation could be demonstrated between demographic characteristics and fatigue. Dutch nurse anesthetists above the age of 50 years show a high fatigue score and therefore need special attention to prevent them from harmful physical and psychological effects and to sustain maximal patient safety. PMID:25109162

  3. When Correction Turns Positive: Processing Corrective Prosody in Dutch

    PubMed Central

    Dimitrova, Diana V.; Stowe, Laurie A.; Hoeks, John C. J.

    2015-01-01

    Current research on spoken language does not provide a consistent picture as to whether prosody, the melody and rhythm of speech, conveys a specific meaning. Perception studies show that English listeners assign meaning to prosodic patterns, and, for instance, associate some accents with contrast, whereas Dutch listeners behave more controversially. In two ERP studies we tested how Dutch listeners process words carrying two types of accents, which either provided new information (new information accents) or corrected information (corrective accents), both in single sentences (experiment 1) and after corrective and new information questions (experiment 2). In both experiments corrective accents elicited a sustained positivity as compared to new information accents, which started earlier in context than in single sentences. The positivity was not modulated by the nature of the preceding question, suggesting that the underlying neural mechanism likely reflects the construction of an interpretation to the accented word, either by identifying an alternative in context or by inferring it when no context is present. Our experimental results provide strong evidence for inferential processes related to prosodic contours in Dutch. PMID:25973607

  4. Rational pharmacotherapy in The Netherlands: formulary management in Dutch hospitals.

    PubMed

    Fijn, R; de Jong-van den Berg, L T; Brouwers, J R

    1999-04-01

    A survey regarding the management of rational pharmacotherapy was conducted among all Dutch general hospitals in 1998. The response was 99% (n = 120). The presence of a drugs and therapeutics committee and antibiotic policies in Dutch general hospitals appears independent of hospital characteristics. However, formulary agreements and treatment guidelines are less likely to be present in hospitals that employ only 1 pharmacist or those served by community pharmacies. More than half of the hospitals claim to have restrictive formulary agreements. Large hospitals, hospitals in the eastern and southern provinces and those served by hospital pharmacies more often tend to have restrictive agreements compared to small hospitals, hospitals in the northern, central, and western provinces, and those served by community pharmacies. Various methods to impose restriction and ensure formulary compliance are mentioned. It must be noted that hospitals tend to operate rather solely regarding the large number of different formularies. Surprisingly just a small majority of pharmacists evaluates formulary agreements positively as a management tool. Many drawbacks appear to be present. The results of this survey indicate that in the future Dutch hospitals will favour disease management (treatment guidelines) over drug management (formulary agreements) in the management of rational pharmacotherapy and that information technology will be used to influence clinicians' prescribing behaviour. PMID:10380234

  5. Sexual orientation of parents and Dutch family law.

    PubMed

    van Nijnatten, C H

    1995-01-01

    A few years ago, the Dutch government asked for advice about the legal consequences of various living arrangements. One of the main issues concerned the legal consequences thereof for children. In a letter to parliament, the Dutch cabinet confirmed that couples of the same sex would be excluded from being awarded children for adoption. Legal and psychological reasons play an important role in the reasoning of the Dutch government. The harmonious development of children is supposed to be at risk when the child is reared by two adults of the same sex. This article sets out psychological theories and the results of recent research which contradict the argumentation presented in a number of recent reports published by the government. The outcome of most research is that gay and lesbian parents 'perform' as well as heterosexual parents. Excluding lesbian and gay parents from taking responsibility for children seems to be a poor policy which does not take into account the social capacities of the population. PMID:8868496

  6. [Dutch-Romanian cooperation in the area of family practice].

    PubMed

    van Es, J C

    2001-10-27

    During the years 1992-2000, there was a cooperative programme between the Romanian general practitioners' association (Societatea Nationala de Medicina Generala) in Romania and the Dutch Foundation for the Advancement of Quality in Healthcare in Romania. A succession of programmes were developed and carried out, which were financed by the Dutch government. The purpose of the cooperative programme was to support the development of Romanian general practice in terms of quality and structure. In the first programme, financed by the Dutch Ministry of Health, Welfare and Sport, about 200 Romanian general practitioners received continuing education. This was followed by a social transformation programme (MATRA) that had two parts: (a) the general practitioners association was supported and advised with respect to improving its organisational efficiency and (b) about 50 carefully selected Romanian general practitioners were trained, in post-academic research, management or teaching. The Romanian authorities accredited these trainees as teachers. The co-operation is being continued in 2001 with the setting up of a sentinel station programme in which 100 Romanian general practitioners collect relevant, representative data on health, illness and practice. PMID:11715598

  7. Relative Age Effects in Dutch Adolescents: Concurrent and Prospective Analyses

    PubMed Central

    Jeronimus, Bertus F.; Stavrakakis, Nikolaos; Veenstra, René; Oldehinkel, Albertine J.

    2015-01-01

    The literature on relative age position effects is rather inconsistent. In this study we examined intra-classroom age position (or relative age) effects on Dutch adolescents’ school progress and performance (as rated by teachers), physical development, temperamental development (fear and frustration), and depressive symptoms, all adjusted for age at the time of measurement. Data were derived from three waves of Tracking Adolescents' Individuals Lives Survey (TRAILS) of 2230 Dutch adolescents (baseline mean age 11.1, SD = 0.6, 51% girls). Albeit relative age predicted school progress (grade retention ORs = 0.83 for each month, skipped grade OR = 1.47, both p<.001), our key observation is the absence of substantial developmental differences as a result of relative age position in Dutch adolescents with a normative school trajectory, in contrast to most literature. For adolescents who had repeated a grade inverse relative age effects were observed, in terms of physical development and school performance, as well as on depressive symptoms, favoring the relatively young. Cross-cultural differences in relative age effect may be partly explained by the decision threshold for grade retention. PMID:26076384

  8. Interpretations of Polymer-Polymer Miscibility.

    ERIC Educational Resources Information Center

    Olabisi, Olagoke

    1981-01-01

    Discusses various aspects of polymeric mixtures, mixtures of structurally different homopolymers, copolymers, terpolymers, and the like. Defines concepts of polymer-polymer miscibility from practical and theoretical viewpoints, and ways of predicting such miscibility. (JN)

  9. Polymer tensiometers in a saline environment.

    NASA Astrophysics Data System (ADS)

    van der Ploeg, Martine; Gooren, H. P. A.; Bakker, G.; Russell, W.; Hoogendam, C. W.; Huiskes, C.; Shouse, P.; de Rooij, G. H.

    2010-05-01

    It is estimated that 20% of all cultivated land and nearly half of the irrigated land is salt-affected, which pose major economic and environmental problems. Salinity may be the result of two processes; dryland and irrigation salinity. Dryland salinity is caused by a rise in the groundwater table, which occurs as a result of the replacement of deep-rooted, perennial native vegetation by shallow-rooted annual species meant for production. Irrigation salinity may occur as a result of poor water quality, poor drainage, or inefficient use of water. Consequently, new strategies to enhance crop yield stability on saline soils represent a major research priority (Botella et al. 2005). At the same time, native vegetation is capable of thriving under saline and/or dry conditions. The plant physiology of such vegetation has been investigated thoroughly, but the relation with in situ soil properties (soil moisture and salinity) may be more difficult to unravel as soil moisture sensors are less sensitive in dry soil, and the signal of most soil moisture content sensors is strongly attenuated by soil salinity. Recently, polymer tensiometer were developed that are able to measure matric potentials (closely related to a soil's moisture status) in dry soils. Polymer tensiometers consist of a solid ceramic, a stainless steel cup and a pressure transducer. The ceramic consist of a support layer and a membrane with 2 nm pore-size to prevent polymer leakage. Between the ceramic membrane and the pressure transducer a tiny chamber is located, which contains the polymer solution. The polymer's osmotic potential strongly reduces the total water potential inside the polymer tensiometer, which causes build-up of osmotic pressure. Polymer tensiometers would thus be an ideal instrument to measure in dry soil, if the polymer inside the tensiometer is not affected by the salts in the soil solution. We will address some key issues regarding the use of POTs in saline environments by showing

  10. Summary of the Dutch S3-guidelines on the treatment of psoriasis 2011. Dutch Society of Dermatology and Venereology.

    PubMed

    Zweegers, J; de Jong, E M G J; Nijsten, T E C; de Bes, J; te Booij, M; Borgonjen, R J; van Cranenburgh, O D; van Deutekom, H; van Everdingen, J J E; de Groot, M; Van Hees, C L M; Hulshuizen, H; Koek, M B G; de Korte, W J A; de Korte, J; Lecluse, L L A; Pasch, M C; Poblete-Gutiérrez, P A; Prens, E P; Seyger, M M B; Thio, H B; Torcque, L A; de Vries, A C Q; van de Kerkhof, P C M; Spuls, Ph I

    2014-03-01

    This document provides a summary of the Dutch S3-guidelines on the treatment of psoriasis. These guidelines were finalized in December 2011 and contain unique chapters on the treatment of psoriasis of the face and flexures, childhood psoriasis as well as the patient's perspective on treatment. They also cover the topical treatment of psoriasis, photo(chemo)therapy, conventional systemic therapy and biological therapy. PMID:24656281

  11. An experimental study of the electronic absorption and fluorescence spectral properties of new p-substituted-N-phenylpyrroles and their electrosynthesized polymers

    NASA Astrophysics Data System (ADS)

    Diaw, A. K. D.; Gningue-Sall, D.; Yassar, A.; Brochon, J.-C.; Henry, E.; Aaron, J.-J.

    2015-01-01

    Electronic absorption and fluorescence spectral properties of new p-substituted-N-phenylpyrroles (N-PhPys), including HOPhPy, MeOPhPy, ThPhPy, PhDPy, DPhDPy, PyPhThThPhPy, and their available, electrosynthesized polymers were investigated. Electronic absorption spectra, fluorescence excitation and emission spectra, fluorescence quantum yields (ΦF) and lifetimes (τF), and other photophysical parameters of these N-PhPy derivatives and their polymers were measured in DMF, DMSO diluted solutions and/or solid state at room temperature. The electronic absorption spectra of N-PhPy derivatives and their polymers included one to several bands, located in the 270-395 nm region, according to the p-phenyl substituent electron-donating effect and conjugated heteroaromatic system length. The fluorescence excitation spectra were characterized by one broad main peak, with, in most cases, one (or more) poorly resolved shoulder (s), appearing in the 270-405 nm region, and their emission spectra were generally constituted of several bands located in the 330-480 nm region. No significant shift of the absorption, fluorescence excitation and emission spectra wavelengths was found upon going from the monomers to the corresponding polymers. ΦF values were high, varying between 0.11 and 0.63, according to the nature of substituents(s) and to the conjugated system extension. Fluorescence decays were mono-exponential for the monomers and poly-exponential for PyPhThThPhPy and for polymers. τF values were relatively short (0.35-5.17 ns), and markedly decreased with the electron-donor character of the phenyl group p-substituent and the conjugated system extension.

  12. An experimental study of the electronic absorption and fluorescence spectral properties of new p-substituted-N-phenylpyrroles and their electrosynthesized polymers.

    PubMed

    Diaw, A K D; Gningue-Sall, D; Yassar, A; Brochon, J-C; Henry, E; Aaron, J-J

    2015-01-25

    Electronic absorption and fluorescence spectral properties of new p-substituted-N-phenylpyrroles (N-PhPys), including HOPhPy, MeOPhPy, ThPhPy, PhDPy, DPhDPy, PyPhThThPhPy, and their available, electrosynthesized polymers were investigated. Electronic absorption spectra, fluorescence excitation and emission spectra, fluorescence quantum yields (ΦF) and lifetimes (τF), and other photophysical parameters of these N-PhPy derivatives and their polymers were measured in DMF, DMSO diluted solutions and/or solid state at room temperature. The electronic absorption spectra of N-PhPy derivatives and their polymers included one to several bands, located in the 270-395 nm region, according to the p-phenyl substituent electron-donating effect and conjugated heteroaromatic system length. The fluorescence excitation spectra were characterized by one broad main peak, with, in most cases, one (or more) poorly resolved shoulder (s), appearing in the 270-405 nm region, and their emission spectra were generally constituted of several bands located in the 330-480 nm region. No significant shift of the absorption, fluorescence excitation and emission spectra wavelengths was found upon going from the monomers to the corresponding polymers. ΦF values were high, varying between 0.11 and 0.63, according to the nature of substituents(s) and to the conjugated system extension. Fluorescence decays were mono-exponential for the monomers and poly-exponential for PyPhThThPhPy and for polymers. τF values were relatively short (0.35-5.17 ns), and markedly decreased with the electron-donor character of the phenyl group p-substituent and the conjugated system extension. PMID:25173528

  13. From Commodity Polymers to Functional Polymers

    PubMed Central

    Xiang, Tao; Wang, Ling-Ren; Ma, Lang; Han, Zhi-Yuan; Wang, Rui; Cheng, Chong; Xia, Yi; Qin, Hui; Zhao, Chang-Sheng

    2014-01-01

    Functional polymers bear specified chemical groups, and have specified physical, chemical, biological, pharmacological, or other uses. To adjust the properties while keeping material usage low, a method for direct synthesis of functional polymers is indispensable. Here we show that various functional polymers can be synthesized by in situ cross-linked polymerization/copolymerization. We demonstrate that the polymers synthesized by the facile method using different functional monomers own outstanding pH-sensitivity and pH-reversibility, antifouling property, antibacterial, and anticoagulant property. Our study opens a route for the functionalization of commodity polymers, which lead to important advances in polymeric materials applications. PMID:24710333

  14. Shape memory polymers

    DOEpatents

    Wilson, Thomas S.; Bearinger, Jane P.

    2015-06-09

    New shape memory polymer compositions, methods for synthesizing new shape memory polymers, and apparatus comprising an actuator and a shape memory polymer wherein the shape memory polymer comprises at least a portion of the actuator. A shape memory polymer comprising a polymer composition which physically forms a network structure wherein the polymer composition has shape-memory behavior and can be formed into a permanent primary shape, re-formed into a stable secondary shape, and controllably actuated to recover the permanent primary shape. Polymers have optimal aliphatic network structures due to minimization of dangling chains by using monomers that are symmetrical and that have matching amine and hydroxyl groups providing polymers and polymer foams with clarity, tight (narrow temperature range) single transitions, and high shape recovery and recovery force that are especially useful for implanting in the human body.

  15. Choices in Dutch health care: mixing strategies and responsibilities.

    PubMed

    van der Grinten, T E; Kasdorp, J P

    1999-12-01

    In the light of experience that choices in health care appear to be not so much hindered by a lack of insight into how choices should be made in theory, as uncertainty as to how choices could be made in practice, this paper sets out to deepen our insight into the dynamics of health care policy making within the concrete socio-economic and political context. The paper examines how Dutch policy-makers have dealt with the priority issue in health care over the past 10 years by means of a gradual incremental approach. In this approach, use is made of a mix of strategies and shared responsibilities, with an important role for the actors at the meso and the micro levels; while at the same time, the government has not abandoned the tried and trusted policy of national rationing (i.e. keeping the production capacity limited and setting a ceiling on production in order to resist the pressure on the public system of Dutch health care). Looking at the declining percentage of Gross National Product assigned to health care annually, the broad accessibility and the good overall quality of Dutch health care, it may be concluded that the issue of choice has not come off badly under this mixed approach. The degree to which the system can respond adequately to likely developments, such as a recession, worsening waiting lists, further liberalisation (i.e. the application of market forces in health care) and, by way of extension, the ongoing integration of 'Europe' is questioned. PMID:10827303

  16. Prevalence of intramammary infection in Dutch dairy herds.

    PubMed

    Sampimon, Otlis; Barkema, Herman W; Berends, Inge; Sol, Jan; Lam, Theo

    2009-05-01

    A survey was carried out in 2003 in 49 dairy herds to determine the overall and pathogen-specific prevalence of intramammary infection (IMI) in Dutch dairy herds, and to compare the distribution with four studies performed from 1973 to 1985 in The Netherlands. Herds were randomly selected stratified over the 12 Dutch provinces, had at least 40 lactating cows and participated in the Dutch milk recording system. Quarter milk samples were collected from all 408 cows with a somatic cell count (SCC) >or=250,000 cells/ml and 145 heifers with SCC >or=150,000 cells/ml at the last milk test before the farm visit. Additionally, samples were collected from 519 (approximately 25%) of the remaining low-SCC cows and heifers with a SCC at the last milk test before the farm visit of <250 000 and <150 000 cells/ml, respectively. Bacterial growth occurred in 37.3% of milk samples of high-SCC cows and in 21.1% of low-SCC cows. Coagulase-negative staphylococci (CNS) were the most frequently isolated group of bacteria (10.8% of quarters) and were found in all herds. Prevalence of Staphylococcus aureus IMI was lower in 2003 than in 1973, respectively 1.8% and 6.2% of quarters. Prevalence of Streptococcus uberis and Str. dysgalactiae IMI was almost the same in the five samplings during the 30-year period, at 1.1-1.7 and 0.9-1.5%, respectively. Str. agalactiae was not found in this study. Prevalence of CNS IMI was higher in lactating heifers, while prevalence of Str. uberis, Str. dysgalactiae and penicillin-resistant Staph. aureus IMI was higher in older cows. Because distribution of pathogens changes over time, herd-level samples for bacteriological culturing must be taken regularly to monitor udder health. Additionally, national mastitis prevalence studies give important information through monitoring the national udder health status. PMID:19121233

  17. Secular trend of dental development in Dutch children.

    PubMed

    Vucic, Strahinja; de Vries, Esther; Eilers, Paul H C; Willemsen, Sten P; Kuijpers, Mette A R; Prahl-Andersen, Birte; Jaddoe, Vincent W V; Hofman, Albert; Wolvius, Eppo B; Ongkosuwito, Edwin M

    2014-09-01

    Many studies have established dental age standards for different populations; however, very few studies have investigated whether dental development is stable over time on a population level. Therefore, the aim of this study was to analyze changes in dental maturity in Dutch children born between 1961 and 2004. We used 2,655 dental panoramic radiographs of 2- to 16-year-old Dutch children from studies performed in three major cities in the Netherlands. Based on a trend in children born between 1961 and 1994, we predicted that a child of a certain age and gender born in 1963 achieved the same dental maturity on average, 1.5 years later than a child of the same age born 40 years later. After adjusting for the birth year of a child in the analysis, the regression coefficient of the city variable was reduced by 56.6% and it remained statistically significant. The observed trend from 1961 to 1994 was extrapolated to 9- to 10-year-old children born in 2002-2004, and validation with the other samples of children with the same characteristics showed that 95.9%-96.8% of the children had dental maturity within the 95% of the predicted range. Dental maturity score was significantly and positively associated with the year of birth, gender, and age in Dutch children, indicating a trend in earlier dental development during the observation period, 1961-2004. These findings highlight the necessity of taking the year of birth into account when assessing dental development within a population with a wider time span. PMID:24912457

  18. Implicit Motivational Processes Underlying Smoking in American and Dutch Adolescents

    PubMed Central

    Larsen, Helle; Kong, Grace; Becker, Daniela; Cousijn, Janna; Boendermaker, Wouter; Cavallo, Dana; Krishnan-Sarin, Suchitra; Wiers, Reinout

    2014-01-01

    Introduction: Research demonstrates that cognitive biases toward drug-related stimuli are correlated with substance use. This study aimed to investigate differences in cognitive biases (i.e., approach bias, attentional bias, and memory associations) between smoking and non-smoking adolescents in the US and the Netherlands. Within the group of smokers, we examined the relative predictive value of the cognitive biases and impulsivity related constructs (including inhibition skills, working memory, and risk taking) on daily smoking and nicotine dependence. Method: A total of 125 American and Dutch adolescent smokers (n = 67) and non-smokers (n = 58) between 13 and 18 years old participated. Participants completed the smoking approach–avoidance task, the classical and emotional Stroop task, brief implicit associations task, balloon analog risk task, the self-ordering pointing task, and a questionnaire assessing level of nicotine dependence and smoking behavior. Results: The analytical sample consisted of 56 Dutch adolescents (27 smokers and 29 non-smokers) and 37 American adolescents (19 smokers and 18 non-smokers). No differences in cognitive biases between smokers and non-smokers were found. Generally, Dutch adolescents demonstrated an avoidance bias toward both smoking and neutral stimuli whereas the American adolescents did not demonstrate a bias. Within the group of smokers, regression analyses showed that stronger attentional bias and weaker inhibition skills predicted greater nicotine dependence while weak working memory predicted more daily cigarette use. Conclusion: Attentional bias, inhibition skills, and working memory might be important factors explaining smoking in adolescence. Cultural differences in approach–avoidance bias should be considered in future research. PMID:24904435

  19. Eliminating Social Inequality by Reinforcing Standard Language Ideology? Language Policy for Dutch in Flemish Schools

    ERIC Educational Resources Information Center

    Delarue, Steven; De Caluwe, Johan

    2015-01-01

    Flanders, the northern, Dutch-speaking part of Belgium, is experiencing growing intra- and interlingual diversity. On the intralingual level, Tussentaal ("in-between-language") has emerged as a cluster of intermediate varieties between the Flemish dialects and Standard Dutch, gradually becoming "the" colloquial language. At the…

  20. Articles, Adjectives and Age of Onset: The Acquisition of Dutch Grammatical Gender

    ERIC Educational Resources Information Center

    Blom, Elma; Polisenska, Daniela; Weerman, Fred

    2008-01-01

    A comparison of the error profiles of monolingual (child L1) learners of Dutch, Moroccan children (child L2) and Moroccan adults (adult L2) learning Dutch as their L2 shows that participants in all groups massively overgeneralize [-neuter] articles to [+neuter] contexts. In all groups, the reverse gender mistake infrequently occurs. Gender…

  1. In the Shadow of Tolerance: The Discursive Context of Dutch-Born Muslim Youth

    ERIC Educational Resources Information Center

    Zaal, Mayida

    2014-01-01

    Despite a public discourse on tolerance, anxiety about immigrants, Islam and the preservation of Dutch values has amplified fear of Muslim youth in the Netherlands. In this context, Dutch-born Muslim youth endure social and systemic discrimination that affects all aspects of their futures, including available educational opportunities and…

  2. Parent Involvement as Professionalization: Professionals' Struggle for Power in Dutch Urban Deprived Areas

    ERIC Educational Resources Information Center

    van den Berg, Marguerite; van Reekum, Rogier

    2011-01-01

    Parent involvement policies have been central in the Dutch push towards educational governance. How the implementation of these policies plays out on the ground is context-dependent. The ethnic and class cleavages impacting the Dutch educational system should be taken into account. On the basis of 50 in-depth interviews with teachers, social…

  3. Observations of the 1761 and 1769 transits of Venus from Batavia (Dutch East Indies)

    NASA Astrophysics Data System (ADS)

    van Gent, Robert H.

    2005-04-01

    This paper discusses the observations of the 1761 and 1769 transits of Venus by the Dutch-German clergyman Johan Maurits Mohr (1716-1775) from Batavia (Dutch East Indies). We will investigate how Mohr became interested in observing this phenomenon and how he made the necessary preparations. Finally, the fate of his observatory and his instruments will be discussed.

  4. Eight Years of Specialist Training of Dutch Intellectual Disability Physicians: Results of Scientific Research Education

    ERIC Educational Resources Information Center

    Evenhuis, Heleen M.; Penning, Corine

    2009-01-01

    Training in scientific research methods and skills is a vital part of Dutch specialist training in intellectual disability medicine. The authors evaluated results of such training at one Dutch university medical facility that had an obligatory research program involving projects conducted by the physicians-in-training (topics, teamwork, acquired…

  5. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following requirements apply to all bridges across Newtown Creek, Dutch Kills, English Kills, and their tributaries: (1)...

  6. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following requirements apply to all bridges across Newtown Creek, Dutch Kills, English Kills, and their tributaries: (1)...

  7. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following requirements apply to all bridges across Newtown Creek, Dutch Kills, English Kills, and their tributaries: (1)...

  8. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following requirements apply to all bridges across Newtown Creek, Dutch Kills, English Kills, and their tributaries: (1)...

  9. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following requirements apply to all bridges across Newtown Creek, Dutch Kills, English Kills, and their tributaries: (1)...

  10. Modeling the Developmental Patterning of Finiteness Marking in English, Dutch, German, and Spanish Using MOSAIC

    ERIC Educational Resources Information Center

    Freudenthal, Daniel; Pine, Julian M.; Aguado-Orea, Javier; Gobet, Fernand

    2007-01-01

    In this study, we apply MOSAIC (model of syntax acquisition in children) to the simulation of the developmental patterning of children's optional infinitive (OI) errors in 4 languages: English, Dutch, German, and Spanish. MOSAIC, which has already simulated this phenomenon in Dutch and English, now implements a learning mechanism that better…

  11. Modeling the Development of Children's Use of Optional Infinitives in Dutch and English Using MOSAIC

    ERIC Educational Resources Information Center

    Freudenthal, Daniel; Pine, Julian M.; Gobet, Fernand

    2006-01-01

    In this study we use a computational model of language learning called model of syntax acquisition in children (MOSAIC) to investigate the extent to which the optional infinitive (OI) phenomenon in Dutch and English can be explained in terms of a resource-limited distributional analysis of Dutch and English child-directed speech. The results show…

  12. Modality, Infinitives, and Finite Bare Verbs in Dutch and English Child Language

    ERIC Educational Resources Information Center

    Blom, Elma

    2007-01-01

    This article focuses on the meaning of nonfinite clauses ("root infinitives") in Dutch and English child language. I present experimental and naturalistic data confirming the claim that Dutch root infinitives are more often modal than English root infinitives. This cross-linguistic difference is significantly smaller than previously assumed,…

  13. Production and Processing of Subject-Verb Agreement in Monolingual Dutch Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Blom, Elma; Vasic, Nada; de Jong, Jan

    2014-01-01

    Purpose: In this study, the authors investigated whether errors with subject-verb agreement in monolingual Dutch children with specific language impairment (SLI) are influenced by verb phonology. In addition, the productive and receptive abilities of Dutch acquiring children with SLI regarding agreement inflection were compared. Method: An SLI…

  14. Zertifikat Niederlaendisch: Examen en getuigschrift Nederlands als vreemde taal (Certificate in Dutch)

    ERIC Educational Resources Information Center

    Beersmans, Frans; Sudhoelter, Juergen

    1976-01-01

    An interim report on preparations for designing an examination in Dutch. The "unit-credit system" proposed by the Council of Europe is being used. The Dutch certificate will be comparable to the certificates given by the British Council and by the People's Universities. Sample portions are given. (Text is in German.) (IFS/WGA)

  15. From Noun to Intensifier: Massa and Massa's in Flemish Varieties of Dutch

    ERIC Educational Resources Information Center

    De Clerck, Bernard; Colleman, Timothy

    2013-01-01

    In this paper a case of synchronic layering is examined in which Dutch "massa" ("mass") and plural "massa's" ("masses") are attested with lexical uses as a collective noun, quantifying uses ("a large quantity of") and intensifying uses ("very")--with plural "massa's" only--in some Flemish varieties of Dutch. Against the background of…

  16. Influence of Linguistic Environment on Children's Language Development: Flemish versus Dutch Children

    ERIC Educational Resources Information Center

    Wiefferink, C. H.; Spaai, G. W. G.; Uilenburg, N.; Vermeij, B. A. M.; De Raeve, L.

    2008-01-01

    In the present study, language development of Dutch children with a cochlear implant (CI) in a bilingual educational setting and Flemish children with a CI in a dominantly monolingual educational setting is compared. In addition, we compared the development of spoken language with the development of sign language in Dutch children. Eighteen…

  17. Phoneme Awareness, Vocabulary and Word Decoding in Monolingual and Bilingual Dutch Children

    ERIC Educational Resources Information Center

    Janssen, Marije; Bosman, Anna M. T.; Leseman, Paul P. M.

    2013-01-01

    The aim of this study was to investigate whether bilingually raised children in the Netherlands, who receive literacy instruction in their second language only, show an advantage on Dutch phoneme-awareness tasks compared with monolingual Dutch-speaking children. Language performance of a group of 47 immigrant first-grade children with various…

  18. Asymmetries in the Acquisition of Subject-Verb Agreement in Dutch: Evidence from Comprehension and Production

    ERIC Educational Resources Information Center

    Verhagen, Josje; Blom, Elma

    2014-01-01

    Across languages, children do not comprehend 3SG/3PL subject-verb agreement before age five, despite early mastery in spontaneous speech. This study investigates subject-verb agreement in a language hitherto not studied in this respect, namely Dutch. The authors examine if (1) Dutch two- and three-year-olds comprehend subject-verb agreement and…

  19. Changing Places: A Cross-Language Perspective on Frequency and Family Size in Dutch and Hebrew

    ERIC Educational Resources Information Center

    Moscoso del Prado Martin, Fermin; Deutsch, Avital; Frost, Ram; Schreuder, Robert; De Jong, Nivja H.; Baayen, R. Harald

    2005-01-01

    This study uses the morphological family size effect as a tool for exploring the degree of isomorphism in the networks of morphologically related words in the Hebrew and Dutch mental lexicon. Hebrew and Dutch are genetically unrelated, and they structure their morphologically complex words in very different ways. Two visual lexical decision…

  20. A Comparison of Dutch and US Teachers' Perceptions of the Incidence and Management of ADHD

    ERIC Educational Resources Information Center

    Havey, J. Michael

    2007-01-01

    Dutch and US teachers were questioned about their perceptions of the incidence and causes of ADHD, as well as their views of appropriate treatments. Dutch teachers were more likely than US teachers to think the etiology of the disorder lay in biochemistry, while US teachers were more likely to believe in a combination of environmental and…

  1. Speech Rate in a Pluricentric Language: A Comparison between Dutch in Belgium and the Netherlands

    ERIC Educational Resources Information Center

    Verhoeven, Jo; De Pauw, Guy; Kloots, Hanne

    2004-01-01

    This paper investigates speech rate in two standard national varieties of Dutch on the basis of 160 15 mins conversations with native speakers who belong to four different regions in the Netherlands and four in the Dutch-speaking part of Belgium (Flanders). Speech rate was quantified as articulation rate and speaking rate, both expressed as the…

  2. Patient safety in Dutch primary care: a study protocol

    PubMed Central

    2010-01-01

    Background Insight into the frequency and seriousness of potentially unsafe situations may be the first step towards improving patient safety. Most patient safety attention has been paid to patient safety in hospitals. However, in many countries, patients receive most of their healthcare in primary care settings. There is little concrete information about patient safety in primary care in the Netherlands. The overall aim of this study was to provide insight into the current patient safety issues in Dutch general practices, out-of-hours primary care centres, general dental practices, midwifery practices, and allied healthcare practices. The objectives of this study are: to determine the frequency, type, impact, and causes of incidents found in the records of primary care patients; to determine the type, impact, and causes of incidents reported by Dutch healthcare professionals; and to provide insight into patient safety management in primary care practices. Design and methods The study consists of three parts: a retrospective patient record study of 1,000 records per practice type was conducted to determine the frequency, type, impact, and causes of incidents found in the records of primary care patients (objective one); a prospective component concerns an incident-reporting study in each of the participating practices, during two successive weeks, to determine the type, impact, and causes of incidents reported by Dutch healthcare professionals (objective two); to provide insight into patient safety management in Dutch primary care practices (objective three), we surveyed organizational and cultural items relating to patient safety. We analysed the incidents found in the retrospective patient record study and the prospective incident-reporting study by type of incident, causes (Eindhoven Classification Model), actual harm (severity-of-outcome domain of the International Taxonomy of Medical Errors in Primary Care), and probability of severe harm or death. Discussion

  3. Victimization and Suicidality Among Dutch Lesbian, Gay, and Bisexual Youths

    PubMed Central

    Bos, Henny M. W.; van Lisdonk, Jantine; Keuzenkamp, Saskia; Sandfort, Theo G. M.

    2013-01-01

    We examined Netherlands Institute for Social Research data, collected between May and August 2009, on 274 Dutch lesbian, gay, and bisexual youths. The data showed that victimization at school was associated with suicidal ideation and actual suicide attempts. Homophobic rejection by parents was also associated with actual suicide attempts. Suicidality in this population could be reduced by supporting coping strategies of lesbian, gay, and bisexual youths who are confronted with stigmatization by peers and parents, and by schools actively promoting acceptance of same-sex sexuality. PMID:23153134

  4. Teaching about Flame Retardants. A Joint Israeli-Dutch Project

    NASA Astrophysics Data System (ADS)

    Kesner, Miri; de Vos, Wobbe

    2001-01-01

    Flame retardants make interesting chemistry and moreover, the chemistry is highly relevant from an everyday life point of view. This article reports on a joint Israeli-Dutch project aimed at teaching the production, properties, and applications of some bromine-containing flame retardants, including their environmental aspects, in secondary education. We provide information on the nature of flame retardants in general and the mechanisms of flame retardation. In addition, we offer a complete pedagogical presentation of the topic, including the use of video and some simple laboratory experiments, that was developed and successfully implemented in both countries.

    Featured on the Cover

  5. Dutch Minister of Science Visits ESO Facilities in Chile

    NASA Astrophysics Data System (ADS)

    2005-05-01

    Mrs. Maria van der Hoeven, the Dutch Minister of Education, Culture and Science, who travelled to the Republic of Chile, arrived at the ESO Paranal Observatory on Friday afternoon, May 13, 2005. The Minister was accompanied, among others, by the Dutch Ambassador to Chile, Mr. Hinkinus Nijenhuis, and Mr. Cornelis van Bochove, the Dutch Director of Science. The distinguished visitors were able to acquaint themselves with one of the foremost European research facilities, the ESO Very Large Telescope (VLT), during an overnight stay at this remote site, and later, with the next major world facility in sub-millimetre and millimetre astronomy, the Atacama Large Millimeter Array (ALMA). At Paranal, the guests were welcomed by the ESO Director General, Dr. Catherine Cesarsky; the ESO Council President, Prof. Piet van der Kruit; the ESO Representative in Chile, Prof. Felix Mirabel; the Director of the La Silla Paranal Observatory, Dr. Jason Spyromilio; by one of the Dutch members of the ESO Council, Prof. Tim de Zeeuw; by the renowned astrophysicist from Leiden, Prof. Ewine van Dishoek, as well as by ESO staff members. The visitors were shown the various high-tech installations at the observatory, including many of the large, front-line VLT astronomical instruments that have been built in collaboration between ESO and European research institutes. Explanations were given by ESO astronomers and engineers and the Minister gained a good impression of the wide range of exciting research programmes that are carried out with the VLT. Having enjoyed the spectacular sunset over the Pacific Ocean from the Paranal deck, the Minister visited the VLT Control Room from where the four 8.2-m Unit Telescopes and the VLT Interferometer (VLTI) are operated. Here, the Minister was invited to follow an observing sequence at the console of the Kueyen (UT2) and Melipal (UT3) telescopes. "I was very impressed, not just by the technology and the science, but most of all by all the people involved

  6. Do Mothers Have the Right to Bring up Their Own Children? How Facts Do Not Determine (Dutch) Government Policy

    ERIC Educational Resources Information Center

    Allewijn, Ellen

    2010-01-01

    The Dutch government has a double moral message for Dutch parents. On the one hand, they expect mothers to work more hours outside the home; on the other hand, they expect parents to perform better in their parental tasks. New research shows again that in spite of all stimulation measures, Dutch women with children prefer their part-time jobs, and…

  7. Social Integration and Religious Identity Expression among Dutch Muslims: The Role of Minority and Majority Group Contact

    ERIC Educational Resources Information Center

    Maliepaard, Mieke; Phalet, Karen

    2012-01-01

    Against the background of contrasting religious versus secular norms in immigrant communities and in Dutch society, this study examines how religious identity expression is related to the social integration of Dutch Muslims within (a) Turkish or Moroccan minority groups and (b) Dutch majority groups. Using nationally representative survey data (N…

  8. Phonological and morphological consistency in the acquisition of vowel duration spelling in Dutch and German.

    PubMed

    Landerl, Karin; Reitsma, Pieter

    2005-12-01

    In Dutch, vowel duration spelling is phonologically consistent but morphologically inconsistent (e.g., paar-paren). In German, it is phonologically inconsistent but morphologically consistent (e.g., Paar-Paare). Contrasting the two orthographies allowed us to examine the role of phonological and morphological consistency in the acquisition of the same orthographic feature. Dutch and German children in Grades 2 to 4 spelled singular and plural word forms and in a second task identified the correct spelling of singular and plural forms of the same nonword. Dutch children were better in word spelling, but German children outperformed the Dutch children in nonword selection. Also, whereas German children performed on a similar level for singular and plural items, Dutch children showed a large discrepancy. The results indicate that children use phonological and morphological rules from an early age but that the developmental balance between the two sources of information is constrained by the specific orthography. PMID:15975590

  9. Loop polymer brushes from polymer single crystals

    NASA Astrophysics Data System (ADS)

    Zhou, Tian; Li, Christopher

    2014-03-01

    Loop polymer brushes represent a category of polymer brushes with both chain ends being tethered to a surface or interface with sufficiently high density. Due to this morphological difference, loop brushes exhibit distinct properties compared with traditional polymer brushes with single chain end being tethered. In our study, α, ω-functionalized polycaprolactone (PCL) single crystals were prepared as templates for polymer brush synthesis. By carefully controlling crystallization condition and immobilization, looped polymer brushes were successfully prepared. Comprehensive studies on the morphology and physical properties of these polymer brushes were carried out using Atomic Force Microscopy and FTIR. Advantages of using this method include exclusive loop morphology, high grafting density, controlled tethering sites and tunable loop size.

  10. Polymer Functionalized Nanoparticles in Polymer Nanocomposites

    NASA Astrophysics Data System (ADS)

    Jayaraman, Arthi

    2013-03-01

    Significant interest has grown around the ability to control spatial arrangement of nanoparticles in a polymer nanocomposite to engineer materials with target properties. Past work has shown that one could achieve controlled assembly of nanoparticles in the polymer matrix by functionalizing nanoparticle surfaces with homopolymers. This talk will focus on our recent work using Polymer Reference Interaction Site Model (PRISM) theory and Monte Carlo simulations and GPU-based molecular dynamics simulations to specifically understand how heterogeneity in the polymer functionalization in the form of a) copolymers with varying monomer chemistry and monomer sequence, and b) polydispersity in homopolymer grafts can tune effective interactions between functionalized nanoparticles, and the assembly of functionalized nanoparticles.

  11. Re-Mendable Polymers

    NASA Astrophysics Data System (ADS)

    Bergman, Sheba D.; Wudl, Fred

    Polymers have become an indispensable material resource, representing billions of dollars worth of material consumption every year. The rising prices and exhaust of natural resources such as petroleum, combined with rising environmental concerns, have prompted the development of recyclable and degradable polymers. Polymers that can be reverted back to their monomers or to shorter repolymerizable oligomers, hence, reversible polymers are particularly enticing in this respect because they essentially prevent any material loss with multiple recycling. While reversible polymers have been known for a long time, there has been recent renewed interest in such polymers, since their reversibility can be exploited for repair at the molecular level.

  12. Lipid-absorbing Polymers

    NASA Technical Reports Server (NTRS)

    Marsh, H. E., Jr.; Wallace, C. J.

    1973-01-01

    The removal of bile acids and cholesterol by polymeric absorption is discussed in terms of micelle-polymer interaction. The results obtained with a polymer composed of 75 parts PEO and 25 parts PB plus curing ingredients show an absorption of 305 to 309%, based on original polymer weight. Particle size effects on absorption rate are analyzed. It is concluded that crosslinked polyethylene oxide polymers will absorb water, crosslinked polybutadiene polymers will absorb lipids; neither polymer will absorb appreciable amounts of lipids from micellar solutions of lipids in water.

  13. How to target uncertainty in Dutch invasive cardiovascular care

    PubMed Central

    Jessurun, G.A.J.; Peels, J.O.J.; Zijlstra, F.

    2004-01-01

    Current meetings of the Netherlands Society of Cardiology and the Working Group on Intervention Cardiology have shown that new strategic developments in the Dutch healthcare system have created much turbulence and uncertainty amongst members of the organisations. Both on-site and off-site new cardiac centres with and without surgical backup, respectively, are arising or being planned throughout the Netherlands. These strategic adaptations are related to service delivery failure, despite appropriate quality measures. To understand the reasoning behind this uncertainty and how to deal with it, we need to explore its origin and thinking. Its rationale is based on the assumption that each organisation relies on its ability to survive through innovation and transformation. Cardiologists and cardiac surgeons are key players in a large group of stakeholders participating in the chain of cardiovascular care. In addition, the Dutch healthcare system is deeply embedded in a historical sociopolitical environment. This may explain why ongoing uncertainty may beget more uncertainty. What are the consequences for the content of the route forward? PMID:25696266

  14. Control of VTEC in Dutch livestock and meat production.

    PubMed

    Reinders, R D; Weber, M F; Lipman, L J; Verhoeff, J; Bijker, P G

    2001-05-21

    The Dutch government and the meat industry, recognising VTEC as having important public health, meat quality and economic implications, have taken a number of initiatives within the last 5 years to control VTEC in livestock and meat. These initiatives, brought together last year in a 'Masterplan VTEC', include short-, middle- and long-term priorities. Short-term priorities include advice on interventions in the cases of an outbreak of VTEC associated with a cattle herd, the implementation of handbooks for Good Manufacturing Practice (GMP) in slaughterhouses and deboning plants, and the execution of an action programme on zero-tolerance to faecal contamination of carcasses. Mid-term activities include surveillance of the occurrence of VTEC and other enteropathogens in livestock and meat, and the investigations of VTEC population dynamics in dairy farms, transportation and farm hygiene. In the longer term, this programme aims to produce a system of Integrated Quality Assurance, consolidating effective measures to control VTEC in Dutch livestock and meat, and integrating emerging means for control and prevention. PMID:11407551

  15. Public cancer information by GPs: evaluation of a Dutch campaign.

    PubMed

    Visser, A; Alkema, I; van Koppen, K

    1994-10-01

    A postal survey among Dutch general practitioners (N = 259) investigated to what extent GPs acted as intermediaries in the provision of information about cancer, in order to encourage patients to consult their general practitioners with questions about cancer. The GPs received a box with three types of folders and a poster free of charge. Only few GPs showed resistance to the unsolicited reception of information material. They were positive towards the Dutch Cancer Society and considered it part of their task to provide patients with information about cancer. Nearly all GPs placed the box with folders in their waiting rooms, while 43% put up the poster. The leaflet and the poster entitled 'Don't walk around with questions' were negatively assessed by around half of the GPs due to the generalized information about cancer, which they felt might arouse fear. The GPs tended to make use of the information material if they had a positive opinion of it, ascribed themselves a role in providing information about cancer, and had positive expectations of the campaign. Biographical factors and characteristics of the GPs practice had hardly any influence on the use of the information material. The practical implication and research method used are discussed. Additional study among patients is stressed. PMID:7746761

  16. A change of direction in the Dutch health care system?

    PubMed

    Lapré, R M

    1988-08-01

    The Dutch health care system seems to be undergoing a clear change of direction. The publication of the Report of the Committee of the Structure and Financing of the Health Care System is a prominent document which marks the emergence of a new trend. After an analysis of the characteristics of the Dutch health care system in the periods 1960-1975 and 1975-1985, an account is given of the most important proposals of the committee. The proposals clearly alter the trend towards more governmental involvement. They envisage a more market-oriented approach and freedom of operation while at the same time paying attention to aspects such as solidarity and social justice. The Committee's suggestions include the introduction of a basic insurance scheme for every citizen with a coverage determined by law, and in addition a voluntary supplementary insurance scheme in which the insured can decide what coverage he requires and that the insurer is obliged to accept him. The fact that there is a certain amount of agreement, at least over the direction that the strategy for change should take, justifies the expectation that many of the committee's proposals will be implemented. PMID:10288395

  17. Rationing and competition in the Dutch health-care system.

    PubMed

    Schut, Frederik T; Van de Ven, Wynand P M M

    2005-09-01

    In this paper we examine the goals and effects of health-care policy in the Netherlands over the period 1980--2000. During this period Dutch health-care policy is marked by a peculiar combination of increasingly stringent cost-containment policies alongside a persistent pursuit of market-oriented reforms. The main goal of cost containment was to keep labour costs down under the restriction of universal equal access to health care. Supply and price control policies were quite successful in achieving cost containment, but in due course prolonged quantity rationing began to jeopardise universal physical access to health services. The main goal of market-oriented health-care reforms is to increase the system's efficiency and its responsiveness to patient's needs, while maintaining equal access. The feasibility of the reforms crucially hinges on the realisation of adequate methods of risk adjustment, product classification and quality measurement, an appropriate consumer information system and an effective competition policy. Realising these preconditions requires a lengthy and cautious implementation process. Although considerable progress has been made in setting the appropriate stage for regulated competition in Dutch health care, the role of the market is still limited. PMID:16161190

  18. Playing with Polymers.

    ERIC Educational Resources Information Center

    Chemecology, 1997

    1997-01-01

    Presents an activity that enables students to gain a better understanding of the importance of polymers. Students perform an experiment in which polymer chains of polyvinyl acetate form crosslinks. Includes background information and discussion questions. (DDR)

  19. Introduction to Polymer Chemistry.

    ERIC Educational Resources Information Center

    Harris, Frank W.

    1981-01-01

    Reviews the physical and chemical properties of polymers and the two major methods of polymer synthesis: addition (chain, chain-growth, or chain-reaction), and condensation (step-growth or step-reaction) polymerization. (JN)

  20. Anion exchange polymer electrolytes

    SciTech Connect

    Kim, Yu Seung; Kim, Dae Sik

    2015-06-02

    Anion exchange polymer electrolytes that include guanidinium functionalized polymers may be used as membranes and binders for electrocatalysts in preparation of anodes for electrochemical cells such as solid alkaline fuel cells.

  1. Polymer composites containing nanotubes

    NASA Technical Reports Server (NTRS)

    Bley, Richard A. (Inventor)

    2008-01-01

    The present invention relates to polymer composite materials containing carbon nanotubes, particularly to those containing singled-walled nanotubes. The invention provides a polymer composite comprising one or more base polymers, one or more functionalized m-phenylenevinylene-2,5-disubstituted-p-phenylenevinylene polymers and carbon nanotubes. The invention also relates to functionalized m-phenylenevinylene-2,5-disubstituted-p-phenylenevinylene polymers, particularly to m-phenylenevinylene-2,5-disubstituted-p-phenylenevinylene polymers having side chain functionalization, and more particularly to m-phenylenevinylene-2,5-disubstituted-p-phenylenevinylene polymers having olefin side chains and alkyl epoxy side chains. The invention further relates to methods of making polymer composites comprising carbon nanotubes.

  2. Polymer Fluid Dynamics.

    ERIC Educational Resources Information Center

    Bird, R. Byron

    1980-01-01

    Problems in polymer fluid dynamics are described, including development of constitutive equations, rheometry, kinetic theory, flow visualization, heat transfer studies, flows with phase change, two-phase flow, polymer unit operations, and drag reduction. (JN)

  3. Metal-polymer and polymer-polymer interfaces: Application to conjugated polymer electronic devices

    NASA Astrophysics Data System (ADS)

    Smallfield, Julie Anne Osladil

    The study of metal-polymer and polymer-polymer interfaces is applied to conjugated polymer electronic devices. Conjugated polymers are a class of organic materials which have metallic or semiconducting properties which are being investigated as alternatives to traditional semiconducting materials. When conjugated polymers are used in devices, the interfaces are found to be critical to device performance. X-ray photoelectron spectroscopy (XPS) and ultraviolet photoelectron spectroscopy (UPS), which give information about the atomic and chemical composition, workfunction, and ionization potential of materials, are used to study these interfaces. In studying metal-polymer interfaces, it is shown that the interface between the conjugated polymer fully sulfonated polyaniline (NSPAN) and an aluminum alloy is an active interface, in which copper is extracted by the polymer from the aluminum alloy. This results in the aluminum alloy becoming more resistant to corrosion in a salty environment. The interface between aluminum and NSPAN, as it is found in some light emitting devices (LEDS), is also studied. It is concluded that negative charge is transferred from the aluminum to the polymer, resulting in a thin layer of oxidized aluminum and a more reduced form of the polymer at the interface. In studying polymer-polymer interfaces, it is proposed that NSPAN protonates a pyridine containing polymer at an interface which is also found in some LEDs. This is proposed to be responsible for color variation found in some LEDs. A model system was studied, and protonation at the polymer-polymer interface was directly observed, supporting the earlier proposals. Polymer-polymer interfaces found in SCALE devices, which are LEDs made with three polymer layers, are studied by UPS to determine the band structure of these devices. It is concluded that the EB layers decrease the hole barrier and increase the electron barrier, which leads to better charge balance and a better device. The EB

  4. Prevalence and treatment of personality disorders in Dutch forensic mental health services.

    PubMed

    de Ruiter, Corine; Trestman, Robert L

    2007-01-01

    Offenders with serious personality disorders challenge forensic systems throughout the world. In this article, the authors describe the legal system that shapes the forensic treatment of personality-disordered offenders in the Dutch psychiatric and correctional systems. The evolution of laws and regulations are addressed, as is the bifurcation of treatment between forensic hospitals and correctional settings. Prevalence data of personality disorders in the Dutch systems are presented, and comparisons between the Dutch and American systems are delineated. Current treatment modalities are described. Research initiatives and future directions for the system are presented. PMID:17389350

  5. Semi-automatic coding with ICPC: the Thesaurus, the algorithm and the Dutch subtitles.

    PubMed

    Gebel, R S

    1997-01-01

    In the ICPC Thesaurus Project, which ran from 1990 to 1992, the Dutch translation of the English version of the ICPC-components 1 and 7 was made available for automated coding by structuring and improving the thesaurus and by developing an algorithm for selecting possible ICPC-codes from a set of medical terms given as input to the program. The thesaurus and algorithm are available to the developers of GP information systems and are at present incorporated in all Dutch GP-systems. This paper brings you up to date with the semi-automatic coding system and the so called Dutch subtitles, an extension to the ICPC. PMID:10179584

  6. Native dialect influences second-language vowel perception: Peruvian versus Iberian Spanish learners of Dutch.

    PubMed

    Escudero, Paola; Williams, Daniel

    2012-05-01

    Peruvian Spanish (PS) and Iberian Spanish (IS) learners were tested on their ability to categorically discriminate and identify Dutch vowels. It was predicted that the acoustic differences between the vowel productions of the two dialects, which compare differently to Dutch vowels, would manifest in differential L2 perception for listeners of these two dialects. The results show that although PS learners had higher general L2 proficiency, IS learners were more accurate at discriminating all five contrasts and at identifying six of the L2 Dutch vowels. These findings confirm that acoustic differences in native vowel production lead to differential L2 vowel perception. PMID:22559460

  7. Nanoporous polymer electrolyte

    SciTech Connect

    Elliott, Brian; Nguyen, Vinh

    2012-04-24

    A nanoporous polymer electrolyte and methods for making the polymer electrolyte are disclosed. The polymer electrolyte comprises a crosslinked self-assembly of a polymerizable salt surfactant, wherein the crosslinked self-assembly includes nanopores and wherein the crosslinked self-assembly has a conductivity of at least 1.0.times.10.sup.-6 S/cm at 25.degree. C. The method of making a polymer electrolyte comprises providing a polymerizable salt surfactant. The method further comprises crosslinking the polymerizable salt surfactant to form a nanoporous polymer electrolyte.

  8. Sex differences in risk taking behavior among Dutch cyclists.

    PubMed

    Cobey, Kelly D; Stulp, Gert; Laan, Freek; Buunk, Abraham P; Pollet, Thomas V

    2013-01-01

    The majority of research examining sex differences in risk-taking behavior focuses on overt physical risk measures in which failed risk attempts may result in serious injury or death. The present research describes sex differences in patterns of risk taking in day-to-day behavior among Dutch cyclists. Through three observational studies we test sex differences in risk taking in situations of financial risk (fines for failing to use bike lights, Study 1), theft risk (bike locking behavior, Study 2) as well as physical risk (risky maneuvers, Study 3). Results corroborate previous findings by showing that across these domains men are more inclined to take risks than women. We discuss how these findings might be used in an applied context. PMID:23674522

  9. Secondary traumatization in Dutch couples of World War II survivors.

    PubMed

    Bramsen, Inge; van der Ploeg, Henk M; Twisk, Jos W R

    2002-02-01

    This study examined whether signs of secondary traumatic stress were present in a community sample of couples who experienced World War II. The authors hypothesized that symptoms of posttraumatic stress disorder (PTSD) in either spouse may be predicted not only by his or her own war experiences but also by the war experiences and posttraumatic symptoms of the partner. Approximately 50 years after the end of World War II, 444 couples from a community sample of elderly Dutch citizens answered a questionnaire. A multilevel regression analysis was performed with symptoms of PTSD as the dependent variable. The most important predictors of PTSD symptoms were the number of war events reported by the participant and the current level of PTSD symptoms of his or her spouse. The results lend empirical support to the notion that posttraumatic stress reactions of both members of a couple are not independent from each other. Several explanations of the findings are discussed. PMID:11862996

  10. Intoxication and criminal responsibility in Dutch criminal Law.

    PubMed

    van Kalmthout, A

    1998-09-01

    This article deals with the question in how far an offence committed in the Netherlands under the influence of alcohol or other drugs can be imputed to the offender. Unlike many other countries the Dutch Penal Code does not contain specific provisions with respect to the criminal liability of addicted or intoxicated offenders. In principle, they are held responsible for their offences, even when the dolus or culpa is absent at the moment they commit their offence. Doctrine and jurisprudence found this liability on the principle of 'culpa/dolus in causa', by accepting an anterior dolus or culpa, which is situated at the moment the offender takes alcohol or other drugs. As is shown in this article, the - nondogmatic - interpretation of this culpa in causa doctrine leaves hardly any space for a claim to impunity. PMID:9742271

  11. Secondary traumatization in partners and parents of Dutch peacekeeping soldiers.

    PubMed

    Dirkzwager, Anja J E; Bramsen, Inge; Adèr, Herman; van der Ploeg, Henk M

    2005-06-01

    This study examines secondary traumatization among 708 partners and 332 parents of Dutch peacekeepers (i.e., personnel who participated in military actions implemented by international organizations such as the United Nations). Partners or parents of peacekeepers with 4 levels of posttraumatic stress symptoms were compared on posttraumatic stress, health problems, the quality of the marital relationship, and social support. In comparison with partners of peacekeepers without posttraumatic stress disorder (PTSD) symptoms, partners of peacekeepers with PTSD symptoms reported more sleeping and somatic problems, reported more negative social support, and judged the marital relationship as less favorable. No significant differences were found for parents. Thus, peacekeepers' stress reactions were related to various problems of their partners. A systemic approach to the treatment of persons with PTSD appears appropriate. PMID:15982097

  12. Consumer choice in Dutch health insurance after reform.

    PubMed

    Maarse, Hans; Meulen, Ruud Ter

    2006-03-01

    This article investigates the scope and effects of enhanced consumer choice in health insurance that is presented as a cornerstone of the new health insurance legislation in the Netherlands that will come into effect in 2006. The choice for choice marks the current libertarian trend in Dutch health care policymaking. One of our conclusions is that the scope of enhanced choice should not be overstated due to many legal and non-legal restrictions to it. The consumer choice advocates have great expectations of the impact of enhanced choice. A critical analysis of its impact demonstrates that these expectations may not become true and that enhanced consumer choice should not be perceived as the 'magic bullet' for many problems in health care. PMID:17137018

  13. The Time Course of Verb Processing in Dutch Sentences

    PubMed Central

    Shapiro, Lewis P.; Wester, Femke; Swinney, David A.; Bastiaanse, Roelien

    2012-01-01

    The verb has traditionally been characterized as the central element in a sentence. Nevertheless, the exact role of the verb during the actual ongoing comprehension of a sentence as it unfolds in time remains largely unknown. This paper reports the results of two Cross-Modal Lexical Priming (CMLP) experiments detailing the pattern of verb priming during on-line processing of Dutch sentences. Results are contrasted with data from a third CMLP experiment on priming of nouns in similar sentences. It is demonstrated that the meaning of a matrix verb remains active throughout the entire matrix clause, while this is not the case for the meaning of a subject head noun. Activation of the meaning of the verb only dissipates upon encountering a clear signal as to the start of a new clause. PMID:19452278

  14. Autologous and allogeneic serum eye drops. The Dutch perspective.

    PubMed

    van der Meer, Pieter F; Seghatchian, Jerard; de Korte, Dirk

    2015-08-01

    If regular artificial tears are ineffective for treatment of ocular surface disorders (including extreme dry eye syndrome), serum eye drops (SEDs) may provide a way to relieve the symptoms. However, not all patients are eligible to donate blood to produce autologous SEDs. Therefore, the use of allogeneic SEDs (obtained from voluntary blood donors) should be explored as an alternative for autologous SEDs. The Dutch blood bank organization is currently looking into the possibilities to provide allogeneic SEDs, as (GMP) regulations become stricter, making it for hospitals more difficult to provide autologous SEDs. To demonstrate effectiveness of both autologous and allogeneic SEDs, a clinical trial is planned. The current status of SEDs in The Netherlands is described. This paper is based on summary of the presentation given at the DGTI meeting in Dresden. PMID:26138910

  15. Black Pete through the Eyes of Dutch Children

    PubMed Central

    Mesman, Judi; Janssen, Sofie; van Rosmalen, Lenny

    2016-01-01

    The traditional figure of Black Pete seen during the December festivities around Sinterklaas (the Dutch Santa Claus) in the Netherlands has sparked fierce debates about his racial stereotypical characteristics and his potentially negative effects on children’s opinions about black people. The Black Pete phenomenon has even been discussed by the United Nations Committee on the Elimination of Racial Discrimination, resulting in a report urging the Netherlands to eliminate this form of racial stereotyping. The adult debate about Black Pete is clearly important, but Sinterklaas is essentially a children’s holiday. Surprisingly, there have never been any systematic studies to examine children’s views on Black Pete. The current study is the first to do so. In a sample of 201 children aged 5–7 years, we collected free descriptions of Black Pete, asked children to group him in relation to other figures, and to assign characteristics to him and comparison figures. The results showed that (1) Children are clearly aware of Black Pete’s skin color and subordinate status; (2) Children associate Black Pete more with clowns than with black people; (3) Children evaluate Black Pete very positively, but the positive characteristics do not generalize to their evaluation of black people. The findings illustrate the deep-rooted childhood origins of many Dutch people’s affection for Black Pete and their lack of awareness of his relation to racial stereotypes. This explains the resistance to changing the Black Pete figure and the slowness of the change process on this front. PMID:27322583

  16. [Twisting and turning; the development of the Dutch science shops].

    PubMed

    Lursen, M; Mulder, H; Lieshout, M

    2000-01-01

    The concept of science shops (Wetenschapswinkels) originates from the Netherlands. Science shops were based on the idea that universities had to play a more prominent role in the solution of social problems - an outcome of the discussion, initiated by students, on the democratisation of universities in the early 1970s. Starting as voluntary student organisations supported by individual staff members from the universities, they were devoted to give oppressed minority groups and the financially weak access to scientific research. Slowly, acknowledgement came. Science shops began to receive financial support from university boards. Support also came from the Dutch government. By now science shops have professionalized and most of them are well embedded in their universities. Many developments within society and the universities influenced the work and structure of the science shops. Positive developments were professionalization, growth, becoming embedded, and the introduction of new research themes. There were also negative developments, such as budget cuts and the fact that 'service to society' ceased to be a government objective for the universities. These led to recurring struggles for survival, which were not always won. Interest in the science shop concept has grown in other countries over the last years. In the 1980s, the system spread within Western Europe. Similar activities, based on the Dutch model, have started in North America and Eastern Europe in the 1990s. The activities on the international level led to an E.U. financial project to prepare an international network of science shops, which commenced in 1999. With information exchange and international cooperation as its major goals, the network will create new opportunties for the future. PMID:11640527

  17. Dutch translation and cross-cultural adaptation of the PROMIS® physical function item bank and cognitive pre-test in Dutch arthritis patients

    PubMed Central

    2012-01-01

    Introduction Patient-reported physical function is an established outcome domain in clinical studies in rheumatology. To overcome the limitations of the current generation of questionnaires, the Patient-Reported Outcomes Measurement Information System (PROMIS®) project in the USA has developed calibrated item banks for measuring several domains of health status in people with a wide range of chronic diseases. The aim of this study was to translate and cross-culturally adapt the PROMIS physical function item bank to the Dutch language and to pretest it in a sample of patients with arthritis. Methods The items of the PROMIS physical function item bank were translated using rigorous forward-backward protocols and the translated version was subsequently cognitively pretested in a sample of Dutch patients with rheumatoid arthritis. Results Few issues were encountered in the forward-backward translation. Only 5 of the 124 items to be translated had to be rewritten because of culturally inappropriate content. Subsequent pretesting showed that overall, questions of the Dutch version were understood as they were intended, while only one item required rewriting. Conclusions Results suggest that the translated version of the PROMIS physical function item bank is semantically and conceptually equivalent to the original. Future work will be directed at creating a Dutch-Flemish final version of the item bank to be used in research with Dutch speaking populations. PMID:22390734

  18. High performance polymer development

    NASA Technical Reports Server (NTRS)

    Hergenrother, Paul M.

    1991-01-01

    The term high performance as applied to polymers is generally associated with polymers that operate at high temperatures. High performance is used to describe polymers that perform at temperatures of 177 C or higher. In addition to temperature, other factors obviously influence the performance of polymers such as thermal cycling, stress level, and environmental effects. Some recent developments at NASA Langley in polyimides, poly(arylene ethers), and acetylenic terminated materials are discussed. The high performance/high temperature polymers discussed are representative of the type of work underway at NASA Langley Research Center. Further improvement in these materials as well as the development of new polymers will provide technology to help meet NASA future needs in high performance/high temperature applications. In addition, because of the combination of properties offered by many of these polymers, they should find use in many other applications.

  19. Does Media Use Result in More Active Communicators? Differences Between Native Dutch and Turkish-Dutch Patients in Information-Seeking Behavior and Participation During Consultations With General Practitioners.

    PubMed

    Schinkel, Sanne; Van Weert, Julia C M; Kester, Jorrit A M; Smit, Edith G; Schouten, Barbara C

    2015-08-01

    This study investigates differences between native Dutch and Turkish-Dutch patients with respect to media usage before and patient participation during medical consultations with general practitioners. In addition, the authors assessed the relation between patient participation and communication outcomes. The patients were recruited in the waiting rooms of general practitioners, and 191 patients (117 native Dutch, 74 Turkish-Dutch) completed pre- and postconsultation questionnaires. Of this sample, 120 patients (62.8%; 82 native Dutch, 38 Turkish-Dutch) agreed to have their consultations recorded to measure patient participation. Compared with Turkish-Dutch patients of similar educational levels, results showed that native Dutch patients used different media to search for information, participated to a greater extent during their consultations and were more responsive to their general practitioner. With respect to the Turkish-Dutch patients, media usage was related to increased patient participation, which was correlated with having fewer unfulfilled information needs; however, these relations were not found in the native Dutch patient sample. In conclusion, interventions that enhance participation among ethnic minority patients will better fulfill informational needs when such interventions stimulate information-seeking behavior in that group before a medical consultation. PMID:26073918

  20. Crime and mental disorders among native Dutch and ethnic minority juvenile defendants in the Netherlands.

    PubMed

    Vinkers, David J; Duits, Nils

    2011-01-01

    We examined the prevalence of mental disorders and the recommendations regarding criminal responsibility and treatment in pre-trial mental health evaluations requested by Dutch juvenile courts for youths between the ages of 12 to 17. Youths of native Dutch (n=2694) and of ethnic minority background (n=1393) were compared. The prevalence of mental disorders was similar for both groups (76.8% versus 74.4%). Criminal responsibility in native Dutch youth was more often considered 'diminished' or 'strongly diminished' than in ethnic minority youth. Admission to a juvenile institution was more often recommended for ethnic minority juveniles than for native Dutch juveniles. It remains unclear from our data whether these differences reflect a false stereotype of ethnic minority populations as being more dangerous and threatening. PMID:21420173

  1. Decisionmaking in Environmental Education: Notes from Research in the Dutch NME-VO Project.

    ERIC Educational Resources Information Center

    De Jager, Henk; van der Loo, Frans

    1990-01-01

    The Dutch project on environmental education, which features decision making on environmental issues within its teaching materials, is described. The results of research done on teaching units entitled "Meat" and "Fuel" are outlined. (CW)

  2. The Involvement of Dutch Universities in Development Cooperation: The Current Situation

    ERIC Educational Resources Information Center

    van der Horst, G. J. C.

    1976-01-01

    Discusses the contribution Dutch universities can make to development cooperation through collaboration in the fields of higher education and research with partners from Third World countries. (Author/RK)

  3. Interior building details of Building A, Room A109 Dutch door, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior building details of Building A, Room A109 Dutch door, room A-108 single panel wood door with wood trim northerly view - San Quentin State Prison, Building 22, Point San Quentin, San Quentin, Marin County, CA

  4. Dutch elm disease. (Latest citations from the Life Sciences Collection database). Published Search

    SciTech Connect

    Not Available

    1994-03-01

    The bibliography contains citations concerning the spread and control of Dutch elm disease. Dutch elm disease is a lethal fungal disease in elm trees which is transmitted via bark beetles. Topics included methods to treat the disease and to control the disease-carrying beetle, biochemistry and genetic information on the disease fungus and its phytotoxin, ecological effects of the disease, evidence of fungicide tolerance by the disease fungus, and attempts to breed disease resistant elm trees. Distribution of Dutch elm disease in Iran, Scotland, the United States, Yugoslavia, and Sweden is described. This information is useful, for example, in the development of methods for detection and treatment of Dutch elm disease. (Contains a minimum of 128 citations and includes a subject term index and title list.)

  5. A survey of evidence-based practise among Dutch occupational therapists.

    PubMed

    Döpp, Carola M E; Steultjens, Esther M J; Radel, Jeff

    2012-03-01

    This study explored how the evidenced-based practise (EBP) is perceived by Dutch occupational therapists (OTs), what sources of research data are used to make clinical decisions, and what barriers are identified in implementing EBP. A self-administered, pre-tested, questionnaire was distributed through an email survey and postal mail among the 200 randomly stratified selected OTs out of a total population of 2,019 Dutch OTs. Analyses of data comprised descriptive statistics of all variables and test statistics to evaluate the differences between demographical groups. Dutch OTs have a very positive attitude toward the EBP. Barriers experienced are mostly related to a lack of skills needed to implement the EBP and to the characteristics of the work environment. The attitude, experiences and barriers are mainly similar to research findings in other countries or professions. A unique barrier to the implementation of the EBP found in this study was that Dutch OTs perceived evidence written in a foreign (non-Dutch) language as a barrier to using evidence in non-Dutch languages. The results of the study, derived from a partly representative group of working OTs, implicate universal problems regarding the effective implementation of the EBP. Solutions to increase the implementation of the EBP from an international point of view are called for and need to be evaluated. PMID:22468272

  6. Synkinesis assessment in facial palsy: validation of the Dutch Synkinesis Assessment Questionnaire.

    PubMed

    Kleiss, Ingrid J; Beurskens, Carien H G; Stalmeier, Peep F M; Ingels, Koen J A O; Marres, Henri A M

    2016-06-01

    The objective of this study is to validate an existing health-related quality of life questionnaire for patients with synkinesis in facial palsy for implementation in the Dutch language and culture. The Synkinesis Assessment Questionnaire was translated into the Dutch language using a forward-backward translation method. A pilot test with the translated questionnaire was performed in 10 patients with facial palsy and 10 normal subjects. Finally, cross-cultural adaption was accomplished at our outpatient clinic for facial palsy. Analyses for internal consistency, test-retest reliability, and construct validity were performed. Sixty-six patients completed the Dutch Synkinesis Assessment Questionnaire and the Dutch Facial Disability Index. Cronbach's α, representing internal consistency, was 0.80. Test-retest reliability was 0.53 (Spearman's correlation coefficient, P < 0.01). Correlations with the House-Brackmann score, Sunnybrook score, Facial Disability Index physical function, and social/well-being function were -0.29, 0.20, -0.29, and -0.32, respectively. Correlation with the Sunnybrook synkinesis subscore was 0.50 (Spearman's correlation coefficient). The Dutch Synkinesis Assessment Questionnaire shows good psychometric values and can be implemented in the management of Dutch-speaking patients with facial palsy and synkinesis in the Netherlands. Translation of the instrument into other languages may lead to widespread use, making evaluation, and comparison possible among different providers. PMID:26377698

  7. [Marked similarity between the Dutch Institute for Health Care Improvement guideline 'Aspecific low back pain complaints' and the Dutch College of General Practitioners guideline 'Low back pain'].

    PubMed

    Mazel, J A

    2004-02-14

    The Dutch Institute for Healthcare Improvement's (CBO) guideline on the diagnosis and treatment of aspecific, acute and chronic, low back complaints corresponds in general to the Dutch College of General Practitioners' guideline with regard to the following topics: time-contingent treatment, restricted use of X-ray examination, and the options for non-medical treatment. A noteworthy exception in the CBO-guideline is the suggestion of manipulation of the spine as a possible treatment although there is no mention of proof of effectiveness. PMID:15015244

  8. Frontiers in polymer chemistry.

    PubMed

    Schlüter, A Dieter

    2013-01-01

    The article shows how the initial concept of Staudinger on linear macromolecules was expanded topologically by increasing the cross-section diameter of polymer chains and by introducing sheet polymers with planar rather than the commonly known linear repeat units. The two concrete projects addressed are the synthesis of dendronized and of two-dimensional polymers. It is explained how these novel macromolecules were achieved and which obstacles had to be overcome but also where these frontiers in polymer chemistry might lead to new insights in polymer science in general and novel applications in particular. The article also provides insights into analytical issues because both target macromolecules are in an extraordinarily high molar mass range and contrast/sensitivity issues can turn rather serious in particular for the two-dimensional polymers. PMID:24388233

  9. High Performance Polymers

    NASA Technical Reports Server (NTRS)

    Venumbaka, Sreenivasulu R.; Cassidy, Patrick E.

    2003-01-01

    This report summarizes results from research on high performance polymers. The research areas proposed in this report include: 1) Effort to improve the synthesis and to understand and replicate the dielectric behavior of 6HC17-PEK; 2) Continue preparation and evaluation of flexible, low dielectric silicon- and fluorine- containing polymers with improved toughness; and 3) Synthesis and characterization of high performance polymers containing the spirodilactam moiety.

  10. Polymer concrete patching manual

    NASA Astrophysics Data System (ADS)

    Fontana, J. J.; Bartholomew, J.

    1982-06-01

    The practicality of using polymer concrete to repair deteriorated portland cement concrete bridge decks and pavements was demonstrated. This manual outlines the procedures for using polymer concrete as a rapid patching material to repair deteriorated concrete. The process technology, materials, equipment, and safety provisions used in manufacturing and placing polymer concrete are discussed. Potential users are informed of the various steps necessary to insure successful field applications of the material.

  11. Thermally conductive polymers

    NASA Technical Reports Server (NTRS)

    Byrd, N. R.; Jenkins, R. K.; Lister, J. L. (Inventor)

    1971-01-01

    A thermally conductive polymer is provided having physical and chemical properties suited to use as a medium for potting electrical components. The polymer is prepared from hydroquinone, phenol, and formaldehyde, by conventional procedures employed for the preparation of phenol-formaldehyde resins. While the proportions of the monomers can be varied, a preferred polymer is formed from the monomers in a 1:1:2.4 molar or ratio of hydroquinone:phenol:formaldehyde.

  12. Dutch survey of congenital coronary artery fistulas in adults

    PubMed Central

    Said, S.A.M.; van der Werf, T.

    2006-01-01

    Aims This Dutch survey focused on the clinical presentation, noninvasive and invasive diagnostic methods, and treatment modalities of adult patients with congenital coronary artery fistulas (CAFs). Methods Between 1996 and 2003, the initiative was taken to start a registry on congenital CAFs in adults. In total 71 patients from a diagnostic coronary angiographic population of 30,829 at 28 hospitals were collected from previously developed case report forms. Patient demographic data, clinical presentation, noninvasive and invasive techniques and treatment options were retrospectively collected and analysed. Results Out of 71 patients with angiographically proven CAFs, 51 (72%) had 63 congenital solitary fistulas and 20 (28%) had 31 congenital coronary-ventricular multiple microfistulas. Patients with pseudofistulas were excluded from the registry. Coronary angiograms were independently re-analysed for morphology and specific fistula details. The majority (72%) of the fistulas were unilateral, 24% were bilateral and only 4% were multilateral. The morphological characteristics of these 94 fistulas were as follows: the origin was multiple in 47% and single in 53%; the termination was multiple in 52% and single in 48%; and the pathway of the fistulous vessels was tortuous/multiple in 66%, tortuous/single in 28%, straight/multiple in 3% and straight/single in 3%. Percutaneous transluminal embolisation (PTE) was performed in two (3%) patients; surgical ligation was undertaken in 13 (18%) patients. The overwhelming majority of the patients (56; 79%) were treated with conservative medical management. The total mortality was 6% (4/71) at a mean follow-up period of approximately five years. Cardiac mortality accounted for 4% (3/71); in all three patients, death could possibly be attributed to the presence of the fistula. Conclusion Registry of congenital coronary artery fistulas in adults in the Netherlands is feasible. In spite of restrictions imposed by the Dutch Privacy

  13. Dutch dairy farmers' need for microbiological mastitis diagnostics.

    PubMed

    Griffioen, Karien; Hop, Geralda E; Holstege, Manon M C; Velthuis, Annet G J; Lam, Theo J G M

    2016-07-01

    Although several microbiological mastitis diagnostic tools are currently available, dairy farmers rarely use them to base treatment decisions on. In this study, we conducted a telephone interview among 195 randomly selected Dutch dairy farmers to determine their current use of and their need for microbiological diagnostics for clinical mastitis (CM), subclinical mastitis (SCM), and dry-cow treatment (DCT), followed by the test characteristics they consider important. A structured questionnaire was used, based on face-to-face interviews previously held with other farmers. The answers were registered in a database and analyzed using descriptive statistics and univariable and multivariable models. Antimicrobial treatment decisions for CM, SCM, and DCT were mainly based on clinical signs and somatic cell count. In case of CM, 34% of farmers indicated that they currently submit milk samples for bacteriological culture (BC). This would increase to 71% if an on-farm test resulting in treatment advice within 12 h were available. For SCM, use would increase from 22 to 55%, and for DCT, from 7 to 34%, if the same 12-h test were available. For CM and DCT, the preferred test outcome was advice on which antibiotic to use, according to 58 and 15% of the farmers, respectively. For SCM, the preferred test outcome was the causative bacterium for 38% of the farmers. Farmers who currently submit CM milk samples for BC were 13.1 times more likely to indicate, as the preferred test outcome, advice on which antibiotic to use, compared with farmers who do not currently submit CM milk samples for BC. Fourteen percent of the farmers indicated not being interested at all in microbiological mastitis diagnostics for CM. For SCM and DCT, 27 and 55%, respectively, were not interested in microbiological mastitis diagnostics. Regarding test characteristics that farmers considered important, reliability was most often indicated (44-51% of the farmers). Additionally, a preferred time-to-result of

  14. Implications of Dutch ammonia policy on the livestock sector

    NASA Astrophysics Data System (ADS)

    Lekkerkerk, L. J. A.

    The Dutch livestock sector is responsible for large emissions of ammonia, resulting in an ammonia deposition that greatly exceeds the critical loads for nitrogen and acidifying compounds in a large part of the country. Based on critical loads and technical possibilities for emission reduction, targets for the deposition of ammonia have been defined. According to plans for the Netherlands, in the year 2000 the deposition of ammonia should be reduced to a maximum of 1000 mol c ha -1 yr -1. In 2010 the target is to further reduce the ammonia deposition to 600 mol c ha -1 yr -1. This study examines the consequences of this environmental policy for the Dutch livestock sector. The scenario's are also applicable to regions outside the Netherlands with high livestock density and high levels of ammonia emission and deposition. In most parts of the Netherlands, planned policy measures to abate ammonia emissions are expected to achieve the ammonia deposition target of 1000 mol c ha -1 yr -1. However, extra measures are necessary in regions with non-calcareous sandy soils, which are sensitive to acidification and where livestock density is high. The deposition target can be reached in these regions (mostly in the central, eastern and southern part of the country) by a combination of extra adaptations of animal housing systems to reduce ammonia emissions, together with relocation of holdings to other regions. If the more stringent deposition target of 600 mol c ha -1 yr -1 is to be reached, more efforts from the livestock sector will be required. In most parts of the Netherlands housing systems with low emission rates should reduce the deposition sufficiently. In the central, eastern and southern parts it is impossible to reach the deposition target for ammonia of 600 mol c ha -1 yr -1 with just technical measures. To meet this target will require a radical contraction of the livestock sector in these regions. Additional to measures in the Netherlands, it is important that the

  15. Predictive aging of polymers

    NASA Technical Reports Server (NTRS)

    Cuddihy, Edward F. (Inventor); Willis, Paul B. (Inventor)

    1990-01-01

    A method of predicting aging of polymers operates by heating a polymer in the outdoors to an elevated temperature until a change of property is induced. The test is conducted at a plurality of temperatures to establish a linear Arrhenius plot which is extrapolated to predict the induction period for failure of the polymer at ambient temperature. An Outdoor Photo Thermal Aging Reactor (OPTAR) is also described including a heatable platen for receiving a sheet of polymer, means to heat the platen and switching means such as a photoelectric switch for turning off the heater during dark periods.

  16. Predictive aging of polymers

    NASA Technical Reports Server (NTRS)

    Cuddihy, Edward F. (Inventor); Willis, Paul B. (Inventor)

    1989-01-01

    A method of predicting aging of polymers operates by heating a polymer in the outdoors to an elevated temperature until a change of property is induced. The test is conducted at a plurality of temperatures to establish a linear Arrhenius plot which is extrapolated to predict the induction period for failure of the polymer at ambient temperature. An Outdoor Photo Thermal Aging Reactor (OPTAR) is also described including a heatable platen for receiving a sheet of polymer, means to heat the platen, and switching means such as a photoelectric switch for turning off the heater during dark periods.

  17. Polymers for engineering applications

    SciTech Connect

    Seymour, R.B.

    1987-01-01

    This book provides an introduction to the world of engineering plastics. It discusses the polymers, their properties strengths and limitations. There are 11 chapters, organized so that each chapter builds on the knowledge of the previous material. Coverage includes important polymer concepts, such as molecular structure, bonding, morphology and molecular weight, and polymer properties, such as thermal expansion, thermal transition, electrical properties and viscoelasticity. Details are provided on methods of processing fabrication and on specific families of polymers. The general-purpose polymers are discussed, such as natural and synthetic rubbers, rayon, acrylic and alkyd coatings, polyethylene, polystyrene and polyvinyl chloride (PVC). There's information on high-performance polymers - fibers, elastomers, and coatings. A thorough explanation of the characteristics and qualities of nylons, polyesters, polyimides, neoprene, silicones, polyurethanes and other polymers is given in the same section. Functional polymers with special properties, such as photoconductivity, electric conductivity, piezoelectricity, light sensitivity, and ion exchange; and polymers that are superior to general-purpose plastics, such as ABS, filled polypropylene, and glass-reinforced plastics, are also covered.

  18. Antioxidant Stabilisation of Polymers

    NASA Astrophysics Data System (ADS)

    Shlyapnikov, Yurii A.

    1981-06-01

    Physicochemical aspects of the stabilisation of polymers are discussed. Attention is paid mainly to the aging and stabilisation of polymers under processing conditions. Topics considered are the kinetics and mechanism of the high-temperature oxidation of polymers, critical phenomena in the inhibited oxidation of polymers, the theory of synergism and antagonism among antioxidants, the reasons for differences in efficiency of antioxidants, and certain aspects of the relation between the efficiency of antioxidants and their molecular structure. A list of 132 references is included.

  19. Observations on the history of Dutch physical stature from the late-Middle Ages to the present.

    PubMed

    de Beer, Hans

    2004-03-01

    In the late-Middle Ages and at the onset of the early modern period, the Dutch population was taller than in the first half of the 19th century. This inference is partially based on skeletal evidence, mainly collected by the Dutch physical anthropologist George Maat and his co-workers. A spectacular increase in Dutch heights began in the second half of the 19th century and accelerated in the second half of the 20th century. At the end of the 20th century, the Dutch became tallest in the world. PMID:15463992

  20. Triclosan antimicrobial polymers

    PubMed Central

    Petersen, Richard C.

    2016-01-01

    Triclosan antimicrobial molecular fluctuating energies of nonbonding electron pairs for the oxygen atom by ether bond rotations are reviewed with conformational computational chemistry analyses. Subsequent understanding of triclosan alternating ether bond rotations is able to help explain several material properties in Polymer Science. Unique bond rotation entanglements between triclosan and the polymer chains increase both the mechanical properties of polymer toughness and strength that are enhanced even better through secondary bonding relationships. Further, polymer blend compatibilization is considered due to similar molecular relationships and polarities. With compatibilization of triclosan in polymers a more uniform stability for nonpolar triclosan in the polymer solid state is retained by the antimicrobial for extremely low release with minimum solubility into aqueous solution. As a result, triclosan is projected for long extended lifetimes as an antimicrobial polymer additive. Further, triclosan rapid alternating ether bond rotations disrupt secondary bonding between chain monomers in the resin state to reduce viscosity and enhance polymer blending. Thus, triclosan is considered for a polymer additive with multiple properties to be an antimicrobial with additional benefits as a nonpolar toughening agent and a hydrophobic wetting agent. The triclosan material relationships with alternating ether bond rotations are described through a complete different form of medium by comparisons with known antimicrobial properties that upset bacterial cell membranes through rapid fluctuating mechanomolecular energies. Also, triclosan bond entanglements with secondary bonding can produce structural defects in weak bacterial lipid membranes requiring pliability that can then interfere with cell division. Regarding applications with polymers, triclosan can be incorporated by mixing into a resin system before cure, melt mixed with thermoplastic polymers that set on cooling

  1. Gender Nonconformity, Sexual Orientation, and Dutch Adolescents' Relationship with Peers.

    PubMed

    Bos, Henny; Sandfort, Theo

    2015-07-01

    Same-sex attraction and gender nonconformity have both been shown to negatively affect the relationships of adolescents with their peers. It is not clear, though, whether same-sex attracted adolescents are more likely to have negative peer relationships because they are same-sex attracted or because they are more likely to be gender nonconforming. It is also possible that both stressors affect peer relationships independently or amplify each other in their impact. We explored these questions in a sample of 486 Dutch adolescents (M age = 14.02 years). We found that same-sex attraction and gender nonconformity both had an independent effect and that gender nonconformity moderated, but not mediated, the associations between same-sex attraction and peer relationships at school. Same-sex attraction was more strongly associated with poorer relationships with peers in adolescents who were more gender nonconforming. These findings indicate the importance of including gender nonconformity in the understanding of same-sex attracted adolescents' relationships and suggest that in order to improve same-sex attracted adolescents' social position at school, acceptance of gender diversity should be promoted as well. PMID:25548066

  2. Epidemiology of Campylobacter spp. at two Dutch broiler farms.

    PubMed Central

    Jacobs-Reitsma, W. F.; van de Giessen, A. W.; Bolder, N. M.; Mulder, R. W.

    1995-01-01

    Broiler flocks on two Dutch poultry farms were screened weekly for the presence of campylobacter in fresh caecal droppings during eight consecutive production cycles. Hatchery and fresh litter samples were taken at the start of each new cycle. Water, feed, insects, and faeces of domestic animals, present on the farms were also included in the sampling. Penner serotyping of isolates was used to identify epidemiological factors that contribute to campylobacter colonization in the broiler flocks. Generally, broiler flocks became colonized with campylobacter at about 3-4 weeks of age with isolation percentages of 100%, and stayed colonized up to slaughter. A similar pattern of serotypes was found within the various broiler houses on one farm during one production cycle. New flocks generally showed also a new pattern of serotypes. Most serotypes isolated from the laying hens, pigs, sheep and cattle were different from those isolated from the broilers at the same time. Campylobacter serotypes from darkling beetles inside the broiler houses were identical to the ones isolated from the broilers. No campylobacter was isolated from any of the hatchery, water, feed or fresh litter samples. Conclusive evidence of transmission routes was not found, but results certainly point towards horizontal transmission from the environment. Horizontal transmission from one broiler flock to the next one via a persistent contamination within the broiler house, as well as vertical transmission from breeder flocks via the hatchery to progeny, did not seem to be very likely. PMID:7781729

  3. Phytolith aided paleoenvironmental studies from the Dutch Neolithic

    NASA Astrophysics Data System (ADS)

    Persaits, Gergő; Gulyás, Sándor; Náfrádi, Katalin; Sümegi, Pál; Szalontai, Csaba

    2015-11-01

    There is increasing evidence for crop cultivation at sites of the Neolithic Swifterbant culture from ca. 4300 B.C. onwards. Presence of cereal fields at the Swifterbant S2, S3 and S4 sites has been corroborated from micro morphological studies of soil samples. Swifterbant sites with evidence for cultivated plants are still scarce though and only emerging, and have produced very low numbers of charred cereals only. The major aim of our work was to elucidate the environmental background of the Dutch Neolithic site Swifterbant S4 based on the investigation of phytolith remains retrieved from soil samples. In addition to find evidence for crop cultivation independently from other studies. Samples were taken at 1 cm intervals vertically from the soil section at the central profile of site S4. Additional samples were taken from pocket-like structures and adjacent horizons above and below. Pig coprolites yielded an astonishing phytolith assemblage which was compared to that of the soil samples. A pig tooth also yielded evaluable material via detailed investigation using SEM. The evaluation of phytolith assemblages retrieved from the soil horizons plus those ending up in the droppings of pigs feasting in the area enabled to draw a relatively reliable environmental picture of the area. All these refer to the presence of a Neolithic horticulture (cereal cultivation) under balanced micro-climatic conditions as a result of the vicinity of the nearby floodplain. These findings corroborate those of previous soil micro-morphological studies.

  4. High risk of tick bites in Dutch gardens.

    PubMed

    Mulder, Sara; van Vliet, Arnold J H; Bron, Wichertje A; Gassner, Fedor; Takken, Willem

    2013-12-01

    Lyme borreliosis is the most prevalent tick-borne disease throughout the Northern Hemisphere. Because the disease has large socioeconomic consequences, there is an urgent need to further educate the public to stimulate preventive behavior. Unfortunately, risk factors for tick bites are poorly known. In this study, we determined the habitats and activities at risk for tick bites for people of different age categories using reports of Dutch citizens. Most people, 43%, were bitten in the forest, and an unexpected large number of people reported tick bites from their gardens (31%). Hiking, hobby gardening, and playing were the most-mentioned activities during which tick bites were received; people aged from 50 to 69 and children below 10 were bitten most. Different age categories were bitten in different habitats and during different activities. People aged from 0 to 60 reported most tick bites related to visiting a forest and hiking, whereas people older than 60 were mainly bitten in gardens. The percentage of garden and hobby gardening tick bites increased with age, but was also high for children less than 10 years of age. We suggest that these findings should be taken into account for the development of prevention strategies aiming to decrease the number of Lyme borreliosis cases. PMID:24107214

  5. First high power experiments with the Dutch free electron maser

    NASA Astrophysics Data System (ADS)

    Verhoeven, A. G. A.; Bongers, W. A.; Bratman, V. L.; Caplan, M.; Denisov, G. G.; van Dijk, G.; van der Geer, C. A. J.; Manintveld, P.; Poelman, A. J.; Pluygers, J.; Shmelyov, M. Yu.; Smeets, P. H. M.; Sterk, A. B.; Urbanus, W. H.

    1998-05-01

    A free electron maser (FEM) has been built as a mm-wave source for applications on future fusion research devices such as ITER, the international tokamak experimental reactor [M. A. Makowski, F. Elio, and D. Loeser, April 97, Proc. 10th Workshop on ECE and ECRH, EC10, 549-559. World Scientific (1998)]. A unique feature of the Dutch fusion-FEM is the possibility to tune the frequency over the entire range from 130 to 260 GHz at an output power exceeding 1 MW. In the first phase of the project, a so-called inverse setup is used. The electron gun is mounted inside the high-voltage terminal. The entire beam line was tested successfully with extremely low loss current, lower than 0.05%. This included the accelerating structure up to 2 MV level and the transport through the undulator. First generation of mm-waves was achieved in October 1997. With an electron beam current around 8 A and an accelerator voltage of 1.76 MV the mm-wave pulse starts after 3 μs and lasts for 3 μs, reaching a maximum saturated peak power level of more than 500 kW at a frequency of 200 GHz. Output power, start-up time, and frequency correspond well with simulation results.

  6. Extensive Genetic Diversity within the Dutch Clinical Cryptococcus neoformans Population

    PubMed Central

    Hagen, Ferry; Illnait-Zaragozí, María-Teresa; Meis, Jacques F.; Chew, William H. M.; Curfs-Breuker, Ilse; Mouton, Johan W.; Hoepelman, Andy I. M.; Spanjaard, Lodewijk; Verweij, Paul E.; Kampinga, Greetje A.; Kuijper, Ed J.; Klaassen, Corné H. W.

    2012-01-01

    A set of 300 Dutch Cryptococcus neoformans isolates, obtained from 237 patients during 1977 to 2007, was investigated by determining the mating type, serotype, and AFLP and microsatellite genotype and susceptibility to seven antifungal compounds. Almost half of the studied cases were from HIV-infected patients, followed by a patient group of individuals with other underlying diseases and immunocompetent individuals. The majority of the isolates were mating type α and serotype A, followed by αD isolates and other minor categories. The most frequently observed genotype was AFLP1, distantly followed by AFLP2 and AFLP3. Microsatellite typing revealed a high genetic diversity among serotype A isolates but a lower diversity within the serotype D set of isolates. One patient was infected by multiple AFLP genotypes. Fluconazole and flucytosine had the highest geometric mean MICs of 2.9 and 3.5 μg/ml, respectively, while amphotericin B (0.24 μg/ml), itraconazole (0.08 μg/ml), voriconazole (0.07 μg/ml), posaconazole (0.06 μg/ml), and isavuconazole (0.03 μg/ml) had much lower geometric mean MICs. One isolate had a high flucytosine MIC (>64 μg/ml), while decreased susceptibility (≥16 μg/ml) for flucytosine and fluconazole was found in 9 and 10 C. neoformans isolates, respectively. PMID:22442325

  7. [A limited role for telemedicine on the Dutch intensive care].

    PubMed

    Girbes, Armand R J; Vroom, Margreeth B

    2014-01-01

    The use of telecommunication and information technology has evolved rapidly in many areas. However, it has not kept pace for the organisation of medicine. It can be expected that e-Health will revolutionise the landscape of medicine in the coming years. Due to a shortage of intensivists, with the 24/7 availability of an intensivist in less than 30% of ICUs, tele-ICU care has been introduced in the U.S. with proven beneficial effects on patient outcome and economics. This cannot be compared with the Dutch situation where there are short distances between hospitals, ubiquitous, excellent infrastructure for patient transport and a sufficient number of intensivists. Furthermore, an ICU is not only characterised by its own means in terms of human resources and equipment, but also by the 24/7 availability of other (critical) medical specialities in the hospital. The contribution of tele-ICU is therefore limited in the Netherlands but might play a role for second opinions and consultation for highly specialized expertise. PMID:25534269

  8. Daily hassles reported by Dutch multiple sclerosis patients.

    PubMed

    van der Hiele, Karin; Spliethoff-Kamminga, Noëlle G; Ruimschotel, Rob P; Middelkoop, Huub A; Visser, Leo H

    2012-09-15

    There is growing evidence for the association between stress and relapse risk in multiple sclerosis (MS). The current study focuses on daily hassles, which by their chronic and accumulating nature can cause considerable psychosocial stress. The main aim was to investigate the frequency, associated distress and type of daily hassles encountered by Dutch MS patients from a large community-based sample. We further examined factors associated with high levels of psychosocial stress. Questionnaires concerning demographics, disease characteristics, physical functioning, daily hassles, fatigue, depression and anxiety were completed by 718 MS patients. Three patients younger than 18 were excluded, resulting in 715 patients. Compared with published norm data, more than 50% of the participants reported a high number of daily hassles (57.5%) and high levels of associated distress (55.7%). Frequently mentioned daily hassles concern personal functioning and social developments. A logistic regression model revealed that being female, being younger, having a higher educational level, using benzodiazepines, exhibiting more symptoms of anxiety, and a higher physical impact of fatigue were all independently associated with high levels of psychosocial stress. Our findings may alert clinicians of the high prevalence and impact of daily hassles in MS and underline the need to incorporate stress and anxiety management strategies in (psycho)therapeutic interventions. PMID:22795386

  9. Availability of information on renal function in Dutch community pharmacies.

    PubMed

    Koster, Ellen S; Philbert, Daphne; Noordam, Michelle; Winters, Nina A; Blom, Lyda; Bouvy, Marcel L

    2016-08-01

    Background Early detection and monitoring of impaired renal function may prevent drug related problems. Objective To assess the availability of information on patient's renal function in Dutch community pharmacies, for patients using medication that might need monitoring in case of renal impairment. Methods Per pharmacy, 25 patients aged ≥65 years using at least one drug that requires monitoring, were randomly selected from the pharmacy information system. For these patients, information on renal function [estimated glomerular filtration rate (eGFR)], was obtained from the pharmacy information system. When absent, this information was obtained from the general practitioner (GP). Results Data were collected for 1632 patients. For 1201 patients (74 %) eGFR values were not directly available in the pharmacy, for another 194 patients (12 %) the eGFR value was not up-to-date. For 1082 patients information could be obtained from the GP, resulting in 942 additional recent eGFR values. Finally, recent information on renal function was available for 72 % (n = 1179) of selected patients. Conclusion In patients using drugs that require renal monitoring, information on renal function is often unknown in the pharmacy. For the majority of patients this information can be retrieved from the GP. PMID:27306651

  10. A Dutch Survey on Circumpatellar Electrocautery in Total Knee Arthroplasty

    PubMed Central

    van Jonbergen, Hans-Peter W.; Barnaart, Alexander F.W.; Verheyen, Cees C.P.M.

    2010-01-01

    Introduction: Anterior knee pain following total knee arthroplasty is estimated to occur in 4-49% of patients. Some orthopedic surgeons use circumpatellar electrocautery (diathermy) to reduce the prevalence of postsurgical anterior knee pain; however, the extent of its use is unknown. Materials and Methodology: In April 2009, a postal questionnaire was sent to all 98 departments of orthopedic surgery in The Netherlands. The questions focused on the frequency of total knee arthroplasties, patellar resurfacing, and the use of circumpatellar electrocautery. Results: The response rate was 92%. A total of 18,876 TKAs, 2,096 unicompartmental knee arthroplasties, and 215 patellofemoral arthroplasties are performed yearly in The Netherlands by the responding orthopedic surgeons. Of the orthopedic surgeons performing TKA, 13% always use patellar resurfacing in total knee arthroplasty for osteoarthritis, 49% use selective patellar resurfacing, and 38% never use it. Fifty-six percent of orthopedic surgeons use circumpatellar electrocautery when not resurfacing the patella, and 32% use electrocautery when resurfacing the patella. Conclusion: There is no consensus among Dutch orthopedic surgeons on the use of patellar resurfacing or circumpatellar electrocautery in total knee replacement performed for osteoarthritis. A prospective clinical trial is currently underway to fully evaluate the effect of circumpatellar electrocautery on the prevalence of anterior knee pain following total knee arthroplasty. PMID:21228917

  11. Pendra goes Dutch: lessons for the CE mark in Europe.

    PubMed

    Wentholt, I M E; Hoekstra, J B L; Zwart, A; DeVries, J H

    2005-06-01

    The development of a truly non-invasive continuous glucose sensor is an elusive goal. We describe the rise and fall of the Pendra device. In 2000 the company Pendragon Medical introduced a truly non-invasive continuous glucose-monitoring device. This system was supposed to work through so-called impedance spectroscopy. Pendra was Conformité Européenne (CE) approved in May 2003. For a short time the Pendra was available on the Dutch direct-to-consumer market. A post-marketing reliability study was performed in six type 1 diabetes patients. Mean absolute difference between Pendra glucose values and values obtained through self-monitoring of blood glucose was 52%; the Pearson's correlation coefficient was 35.1%; and a Clarke error grid showed 4.3% of the Pendra readings in the potentially dangerous zone E. We argue that the CE certification process for continuous glucose sensors should be made more transparent, and that a consensus on specific requirements for continuous glucose sensors is needed to prevent patient exposure to potentially dangerous situations. PMID:15871008

  12. The success of SEA in the Dutch planning practice

    SciTech Connect

    Van Buuren, Arwin; Nooteboom, Sibout

    2010-02-15

    In this article we answer the question how Strategic Environmental Assessment (SEA) may assist collaborative planning. We argue that successful collaborative planning generates specific demands on the production of policy-relevant knowledge, which SEA may help to meet. Important criteria for usable knowledge in governance processes are its interactive production, its flexible character to cope with the dynamics of collaborative processes, its openness to stakeholder involvement, and its focus on close interplay between policy and knowledge developers. The SEA procedure may fit well into collaborative planning processes, depending on how policy makers apply and use this procedure. From two rather controversial Dutch planning cases we learn that SEA, applied wisely, plays an important role in realizing meaningful stakeholder involvement, joint fact-finding and interaction between lay people and experts, agreement about the policy problem, the alternative solutions and their effects, and knowledge which is feasible to facilitate decision-making in a context of highly polarized positions and value-laden conflicts. We can conclude that SEA seems to be perhaps not formally intended to facilitate collaborative governance processes, but that it can do so when the users translate its principles in accordance to the general principles of successful collaborative governance and joint fact finding.

  13. Health-related quality of life in epidermolysis bullosa: Validation of the Dutch QOLEB questionnaire and assessment in the Dutch population.

    PubMed

    Yuen, Wing Yan; Frew, John W; Veerman, Kelly; van den Heuvel, Edwin R; Murrell, Dedee F; Jonkman, Marcel F

    2014-07-01

    Defining the health-related quality of life (HRQoL) in patients suffering from the heritable blistering disease epidermolysis bullosa (EB) is important in assessing the efficacy of new treatments. The quality of life in EB questionnaire (QOLEB) is an English 17-item EB-specific HRQoL measurement tool. The aim of this study was to develop a validated and reliable QOLEB in Dutch and assess the HRQoL in Dutch EB patients. The QOLEB was translated to Dutch according to protocol. Fifty-five adult patients across 4 EB subtypes participated. The QOLEB had excellant correlation with the Skindex-29 (ρs = 0.86), good correlation with the SF-36 physical score (ρs = -0.75), and moderate correlation with the SF-36 mental score (ρs = -0.43). The discriminative validity between the 4 different EB subtypes was significant (p = 0.002). The internal consistency was excellent (α = 0.905), and the test-retest reliability strong (ρs = 0.88). In conclusion, the Dutch QOLEB is a reliable and valid instrument for the assessment of the HRQoL in adult EB patients. PMID:24337132

  14. Host responses and metabolic profiles of wood components in Dutch elm hybrids with a contrasting tolerance to Dutch elm disease

    PubMed Central

    Ďurkovič, Jaroslav; Kačík, František; Olčák, Dušan; Kučerová, Veronika; Krajňáková, Jana

    2014-01-01

    Background and Aims Changes occurring in the macromolecular traits of cell wall components in elm wood following attack by Ophiostoma novo-ulmi, the causative agent of Dutch elm disease (DED), are poorly understood. The purpose of this study was to compare host responses and the metabolic profiles of wood components for two Dutch elm (Ulmus) hybrids, ‘Groeneveld’ (a susceptible clone) and ‘Dodoens’ (a tolerant clone), that have contrasting survival strategies upon infection with the current prevalent strain of DED. Methods Ten-year-old plants of the hybrid elms were inoculated with O. novo-ulmi ssp. americana × novo-ulmi. Measurements were made of the content of main cell wall components and extractives, lignin monomer composition, macromolecular traits of cellulose and neutral saccharide composition. Key Results Upon infection, medium molecular weight macromolecules of cellulose were degraded in both the susceptible and tolerant elm hybrids, resulting in the occurrence of secondary cell wall ruptures and cracks in the vessels, but rarely in the fibres. The 13C nuclear magnetic resonance spectra revealed that loss of crystalline and non-crystalline cellulose regions occurred in parallel. The rate of cellulose degradation was influenced by the syringyl:guaiacyl ratio in lignin. Both hybrids commonly responded to the medium molecular weight cellulose degradation with the biosynthesis of high molecular weight macromolecules of cellulose, resulting in a significant increase in values for the degree of polymerization and polydispersity. Other responses of the hybrids included an increase in lignin content, a decrease in relative proportions of d-glucose, and an increase in proportions of d-xylose. Differential responses between the hybrids were found in the syringyl:guaiacyl ratio in lignin. Conclusions In susceptible ‘Groeneveld’ plants, syringyl-rich lignin provided a far greater degree of protection from cellulose degradation than in ‘Dodoens’, but

  15. Quality of life assessment in facial palsy: validation of the Dutch Facial Clinimetric Evaluation Scale.

    PubMed

    Kleiss, Ingrid J; Beurskens, Carien H G; Stalmeier, Peep F M; Ingels, Koen J A O; Marres, Henri A M

    2015-08-01

    This study aimed at validating an existing health-related quality of life questionnaire for patients with facial palsy for implementation in the Dutch language and culture. The Facial Clinimetric Evaluation Scale was translated into the Dutch language using a forward-backward translation method. A pilot test with the translated questionnaire was performed in 10 patients with facial palsy and 10 normal subjects. Finally, cross-cultural adaption was accomplished at our outpatient clinic for facial palsy. Analyses for internal consistency, test-retest reliability, construct validity and responsiveness were performed. Ninety-three patients completed the Dutch Facial Clinimetric Evaluation Scale, the Dutch Facial Disability Index, and the Dutch Short Form (36) Health Survey. Cronbach's α, representing internal consistency, was 0.800. Test-retest reliability was shown by an intraclass correlation coefficient of 0.737. Correlations with the House-Brackmann score, Sunnybrook score, Facial Disability Index physical function, and social/well-being function were -0.292, 0.570, 0.713, and 0.575, respectively. The SF-36 domains correlate best with the FaCE social function domain, with the strongest correlation between the both social function domains (r = 0.576). The FaCE score did statistically significantly increase in 35 patients receiving botulinum toxin type A (P = 0.042, Student t test). The domains 'facial comfort' and 'social function' improved statistically significantly as well (P = 0.022 and P = 0.046, respectively, Student t-test). The Dutch Facial Clinimetric Evaluation Scale shows good psychometric values and can be implemented in the management of Dutch-speaking patients with facial palsy in the Netherlands. Translation of the instrument into other languages may lead to widespread use, making evaluation and comparison possible among different providers. PMID:25628237

  16. Polymers Are Everywhere.

    ERIC Educational Resources Information Center

    Seymour, Raymond B.

    1988-01-01

    Describes the history of the human understanding of polymers from alchemy to modern times. Discusses renaissance chemistry, polymers in the nineteenth century, synthetic elastomers, thermoplastic elastomers, fibers, coatings, adhesives, derivatives of natural rubber, thermosets, step-reaction, and chain polymerization. (CW)

  17. Melons are Branched Polymers

    NASA Astrophysics Data System (ADS)

    Gurau, Razvan; Ryan, James P.

    2014-11-01

    Melonic graphs constitute the family of graphs arising at leading order in the 1/N expansion of tensor models. They were shown to lead to a continuum phase, reminiscent of branched polymers. We show here that they are in fact precisely branched polymers, that is, they possess Hausdorff dimension 2 and spectral dimension 4/3.

  18. Heat resistant polyphosphazene polymers

    NASA Technical Reports Server (NTRS)

    Fewell, L. L.; Allcock, H. R.; Obrien, J. P.; Scopelianos, A. G.

    1981-01-01

    Polymers of carboranyl substituted polyphosphazene are stable at high temperatures and produce insulating char upon pyrolysis. Substituted compounds are prepared by heat polymerizing carboranyl halophosphazene, which is obtained by reacting lithium carborane with, for example, hexachlorocyclotriphosphazene under anhydrous conditions. Chlorine of polymer may be replaced by aryloxy and alkoxy groups.

  19. Polymer based tunneling sensor

    NASA Technical Reports Server (NTRS)

    Cui, Tianhong (Inventor); Wang, Jing (Inventor); Zhao, Yongjun (Inventor)

    2006-01-01

    A process for fabricating a polymer based circuit by the following steps. A mold of a design is formed through a lithography process. The design is transferred to a polymer substrate through a hot embossing process. A metal layer is then deposited over at least part of said design and at least one electrical lead is connected to said metal layer.

  20. Porous polymer media

    DOEpatents

    Shepodd, Timothy J.

    2002-01-01

    Highly crosslinked monolithic porous polymer materials for chromatographic applications. By using solvent compositions that provide not only for polymerization of acrylate monomers in such a fashion that a porous polymer network is formed prior to phase separation but also for exchanging the polymerization solvent for a running buffer using electroosmotic flow, the need for high pressure purging is eliminated. The polymer materials have been shown to be an effective capillary electrochromatographic separations medium at lower field strengths than conventional polymer media. Further, because of their highly crosslinked nature these polymer materials are structurally stable in a wide range of organic and aqueous solvents and over a pH range of 2-12.

  1. Polymer Crystallization under Confinement

    NASA Astrophysics Data System (ADS)

    Floudas, George

    Recent efforts indicated that polymer crystallization under confinement can be substantially different from the bulk. This can have important technological applications for the design of polymeric nanofibers with tunable mechanical strength, processability and optical clarity. However, the question of how, why and when polymers crystallize under confinement is not fully answered. Important studies of polymer crystallization confined to droplets and within the spherical nanodomains of block copolymers emphasized the interplay between heterogeneous and homogeneous nucleation. Herein we report on recent studies1-5 of polymer crystallization under hard confinement provided by model self-ordered AAO nanopores. Important open questions here are on the type of nucleation (homogeneous vs. heterogeneous), the size of critical nucleus, the crystal orientation and the possibility to control the overall crystallinity. Providing answers to these questions is of technological relevance for the understanding of nanocomposites containing semicrystalline polymers. In collaboration with Y. Suzuki, H. Duran, M. Steinhart, H.-J. Butt.

  2. Rapid Polymer Sequencer

    NASA Technical Reports Server (NTRS)

    Stolc, Viktor (Inventor); Brock, Mathew W. (Inventor)

    2011-01-01

    Method and system for rapid and accurate determination of each of a sequence of unknown polymer components, such as nucleic acid components. A self-assembling monolayer of a selected substance is optionally provided on an interior surface of a pipette tip, and the interior surface is immersed in a selected liquid. A selected electrical field is impressed in a longitudinal or transverse direction at the tip, a polymer sequence is passed through the tip, and a change in an electrical current signal is measured as each polymer component passes through the tip. Each measured change in electrical current signals is compared with a database of reference signals, with each reference signal identified with a polymer component, to identify the unknown polymer component. The tip preferably has a pore inner diameter of no more than about 40 nm and is prepared by heating and pulling a very small section of a glass tubing.

  3. Polymers at membranes

    NASA Astrophysics Data System (ADS)

    Breidenich, Markus

    2000-11-01

    The surface of biological cells consists of a lipid membrane and a large amount of various proteins and polymers, which are embedded in the membrane or attached to it. We investigate how membranes are influenced by polymers, which are anchored to the membrane by one end. The entropic pressure exerted by the polymer induces a curvature, which bends the membrane away from the polymer. The resulting membrane shape profile is a cone in the vicinity of the anchor segment and a catenoid far away from it. The perturbative calculations are confirmed by Monte-Carlo simulations. An additional attractive interaction between polymer and membrane reduces the entropically induced curvature. In the limit of strong adsorption, the polymer is localized directly on the membrane surface and does not induce any pressure, i.e. the membrane curvature vanishes. If the polymer is not anchored directly on the membrane surface, but in a non-vanishing anchoring distance, the membrane bends towards the polymer for strong adsorption. In the last part of the thesis, we study membranes under the influence of non-anchored polymers in solution. In the limit of pure steric interactions between the membrane and free polymers, the membrane curves towards the polymers (in contrast to the case of anchored polymers). In the limit of strong adsorption the membrane bends away from the polymers. Die Oberfläche biologischer Zellen besteht aus einer Lipidmembran und einer Vielzahl von Proteinen und Polymeren, die in die Membran eingebaut sind. Die Beeinflussung der Membran durch Polymere, die mit einem Ende an der Membran verankert sind, wird im Rahmen dieser Arbeit anhand eines vereinfachten biomimetischen Systems studiert. Der entropische Druck, den das Polymer durch Stöße auf die Membran ausübt, führt dazu, dass sich die Membran vom Polymer weg krümmt. Die resultierende Membranform ist ein Kegel in der Nähe des Ankers und ein Katenoid in grossem Abstand vom Ankerpunkt. Monte Carlo-Simulationen best

  4. Electroactive polymers for sensing.

    PubMed

    Wang, Tiesheng; Farajollahi, Meisam; Choi, Yeon Sik; Lin, I-Ting; Marshall, Jean E; Thompson, Noel M; Kar-Narayan, Sohini; Madden, John D W; Smoukov, Stoyan K

    2016-08-01

    Electromechanical coupling in electroactive polymers (EAPs) has been widely applied for actuation and is also being increasingly investigated for sensing chemical and mechanical stimuli. EAPs are a unique class of materials, with low-moduli high-strain capabilities and the ability to conform to surfaces of different shapes. These features make them attractive for applications such as wearable sensors and interfacing with soft tissues. Here, we review the major types of EAPs and their sensing mechanisms. These are divided into two classes depending on the main type of charge carrier: ionic EAPs (such as conducting polymers and ionic polymer-metal composites) and electronic EAPs (such as dielectric elastomers, liquid-crystal polymers and piezoelectric polymers). This review is intended to serve as an introduction to the mechanisms of these materials and as a first step in material selection for both researchers and designers of flexible/bendable devices, biocompatible sensors or even robotic tactile sensing units. PMID:27499846

  5. A review of a new Dutch guideline for management of recurrent varicose veins.

    PubMed

    Lawson, James A; Toonder, Irwin M

    2016-03-01

    In 2013, the new Dutch guideline for "Venous Pathology" was published. The guideline was a revision and update from the guideline "Diagnostics and Treatment of Varicose Veins" from 2009 and the guideline "Venous Ulcer" from 2005. A guideline for "Deep Venous Pathology" and one for "Compression Therapy" was added to the overall guideline "Venous Pathology." The chapter about treatment of recurrent varicose veins after initial intervention was recently updated in 2015 and is reviewed here. The Dutch term "recidief varices" or the French "récidive de varices" should be used analogous to the English term "recurrent varicose veins." The DCOP Guideline Development Group Neovarices concluded that "recidief" in Dutch actually suggests recurrence after apparent successful treatment and ignores the natural progression of venous disease in its own right. So the group opted to use the term "neovarices." In the Dutch guideline, neovarices is meant to be an all embracing term for recurrent varicose veins caused by technical or tactical failure, evolvement from residual refluxing veins or natural progression of varicose vein disease at different locations of the treated leg after intervention. This report reviews the most important issues in the treatment of varicose vein recurrence, and discusses conclusions and recommendations of the Dutch Neovarices Guideline Committee. PMID:26916778

  6. Quiet is the new loud: pausing and focus in child and adult Dutch.

    PubMed

    Romøren, Anna Sara H; Chen, Aoju

    2015-03-01

    In a number of languages, prosody is used to highlight new information (or focus). In Dutch, focus is marked by accentuation, whereby focal constituents are accented and post-focal constituents are de-accented. Even if pausing is not traditionally seen as a cue to focus in Dutch, several previous studies have pointed to a possible relationship between pausing and information structure. Considering that Dutch-speaking 4 to 5 year olds are not yet completely proficient in using accentuation for focus and that children generally pause more than adults, we asked whether pausing might be an available parameter for children to manipulate for focus. Sentences with varying focus structure were elicited from 10 Dutch-speaking 4 to 5 year olds and 9 Dutch-speaking adults by means of a picture-matching game. Comparing pause durations before focal and non-focal targets showed pre-target pauses to be significantly longer when the targets were focal than when they were not. Notably, the use of pausing was more robust in the children than in the adults, suggesting that children exploit pausing to mark focus more generally than adults do, at a stage where their mastery of the canonical cues to focus is still developing. PMID:25935935

  7. Bottlebrush Polymer Additives for Binary Polymer Blends

    NASA Astrophysics Data System (ADS)

    Mah, Hui Zhen; Afzali, Pantea; Phan, Hanh; Qi, Luqing; Pesek, Stacy; Verduzco, Rafael; Stein, Gila

    Bottlebrush polymers are highly branched polymers that have been used in applications such as self-assembling photonics, drug delivery and stimuli-responsive surface coatings. However, they have not been widely studied as compatibilizers for polymer blends. In this study, bottlebrush polymers with poly(styrene-r-methyl methacrylate) side chains were used as additives for thin film blends of polystyrene (PS) and poly (methyl methacrylate) (PMMA). The blends were heated above the glass transition temperature to drive phase separation, and the resulting morphology was characterized with atomic force microscopy and optical microscopy. Outcomes were compared with PS/PMMA blends that contain conventional compatibilizers such as linear random copolymers of poly(styrene-r-methyl methacrylate) and diblock PS-PMMA copolymers. The bottlebrush additive accumulates at the PS/PMMA interface and drives the formation of vesicle-like droplets that assemble into longer chains. The continuity of the chains depends on the blend composition, where a network structure is achieved close to the critical composition. This unusual microstructure was not observed with the other additives, and may be a consequence of preferential wetting of the bottlebrush by the PS phase.

  8. Eutrophic urban ponds suffer from cyanobacterial blooms: Dutch examples.

    PubMed

    Waajen, Guido W A M; Faassen, Elisabeth J; Lürling, Miquel

    2014-01-01

    Ponds play an important role in urban areas. However, cyanobacterial blooms counteract the societal need for a good water quality and pose serious health risks for citizens and pets. To provide insight into the extent and possible causes of cyanobacterial problems in urban ponds, we conducted a survey on cyanobacterial blooms and studied three ponds in detail. Among 3,500 urban ponds in the urbanized Dutch province of North Brabant, 125 showed cyanobacterial blooms in the period 2009-2012. This covered 79% of all locations registered for cyanobacterial blooms, despite the fact that urban ponds comprise only 11% of the area of surface water in North Brabant. Dominant bloom-forming genera in urban ponds were Microcystis, Anabaena and Planktothrix. In the three ponds selected for further study, the microcystin concentration of the water peaked at 77 μg l(-1) and in scums at 64,000 μg l(-1), which is considered highly toxic. Microcystin-RR and microcystin-LR were the most prevalent variants in these waters and in scums. Cyanobacterial chlorophyll-a peaked in August with concentrations up to 962 μg l(-1) outside of scums. The ponds were highly eutrophic with mean total phosphorus concentrations between 0.16 and 0.44 mg l(-1), and the sediments were rich in potential releasable phosphorus. High fish stocks dominated by carp lead to bioturbation, which also favours blooms. As urban ponds in North Brabant, and likely in other regions, regularly suffer from cyanobacterial blooms and citizens may easily have contact with the water and may ingest cyanobacterial material during recreational activities, particularly swimming, control of health risk is of importance. Monitoring of cyanobacteria and cyanobacterial toxins in urban ponds is a first step to control health risks. Mitigation strategies should focus on external sources of eutrophication and consider the effect of sediment P release and bioturbation by fish. PMID:24798921

  9. Exposure to polycyclic aromatic hydrocarbons among Dutch children.

    PubMed Central

    van Wijnen, J H; Slob, R; Jongmans-Liedekerken, G; van de Weerdt, R H; Woudenberg, F

    1996-01-01

    We determined the urinary 1-hydroxypyrene (1-HP) concentration and the creatinine-adjusted 1-HP concentration in 644 randomly selected Dutch children, aged 1-6 years and living in five areas with roughly different levels of polycyclic aromatic hydrocarbons (PAHs) in soil and ambient air. The presence of other factors that might influence the exposure to PAHs was studied using a questionnaire. To evaluate the reliability of a single urinary 1-HP determination, measurements were repeated after 3 weeks for approximately 200 children. The mean urinary 1-HP content of the total study population was 2.06 nmol/l. This varied from 1.58 nmol/l in the reference area (Flevoland) to 2.71 nmol/l in the valley of the Geul. Only indoor sources of PAHs showed a small, positive association with urinary 1-HP. The urinary 1-HP concentrations of children from the valley of the Geul were higher (p < 0.01) and those of children from a suburb of Amsterdam were lower (p < 0.01) than those of children from the reference area. The possible ambient environment-related differences were probably too small to be detected in the variations of the intake of PAHs from the daily diet. The reliability of a single 1-HP measurement was low. Similar results were obtained with the creatinine-adjusted data. In one neighborhood built on coal-mine tailings, the urinary 1-HP content in children was weakly but positively associated with the PAH content in the upper soil layer of the garden of their homes. However, this association was not found for the children from the other neighborhood built on coal-mine tailings and with similar PAH levels in soil. PMID:8743441

  10. Manifestations of integrated public health policy in Dutch municipalities.

    PubMed

    Peters, Dorothee; Harting, Janneke; van Oers, Hans; Schuit, Jantine; de Vries, Nanne; Stronks, Karien

    2016-06-01

    Integrated public health policy (IPHP) aims at integrating health considerations into policies of other sectors. Since the limited empirical evidence available may hamper its further development, we systematically analysed empirical manifestations of IPHP, by placing policy strategies along a continuum of less-to-more policy integration, going from intersectoral action (IA) to healthy public policy (HPP) to health in all policies (HiAP). Our case study included 34 municipal projects of the Dutch Gezonde Slagkracht Programme (2009-15), which supports the development and implementation of IPHP on overweight, alcohol and drug abuse, and smoking. Our content analysis of project application forms and interviews with all project leaders used a framework approach involving the policy strategies and the following policy variables: initiator, actors, policy goals, determinants and policy instruments. Most projects showed a combination of policy strategies. However, manifestations of IPHP in overweight projects predominantly involved IA. More policy integration was apparent in alcohol/drugs projects (HPP) and in all-theme projects (HiAP). More policy integration was related to broad goal definitions, which allowed for the involvement of actors representing several policy sectors. This enabled the implementation of a mix of policy instruments. Determinants of health were not explicitly used as a starting point of the policy process. If a policy problem justifies policy integration beyond IA, it might be helpful to start from the determinants of health (epidemiological reality), systematically transform them into policy (policy reality) and set broad policy goals, since this gives actors from other sectors the opportunity to participate. PMID:25500994

  11. Bird mortality following DDT spray for Dutch elm disease

    USGS Publications Warehouse

    Wurster, D.H.; Wurster, C.F.; Strickland, W.N.

    1965-01-01

    Avian populations in Hanover, N. H., a town that has sprayed its elms with DDT for many years in an attempt to control Dutch elm disease, were compared with those in Norwich, Vt., a town 1 mile (1.6 km) west of Hanover that has never sprayed. Hanover applied 109 lb DDT/acre (2.1 kg/hectare) in April 1963, then used Methoxychlor in April 1964. Population surveys were taken regularly during spring and early summer of these years, dead birds were collected in both towns, and 106 birds were analyzed for DDT, DDE, and DDD. Severe mortality of both resident and migrant birds occurred in Hanover during spring 1963, and the evidence implicates DDT as its cause. Robin loss was estimated at 70% of the resident population, or 350 to 400 individuals, but mortality among other species of widely varied feeding habits was also substantial. Feeding habits suggest that some birds acquired the toxicant by eating living insects carrying DDT, presenting the paradox of survival of the intended DDT victims, and death, instead, of insectivorous birds. Organ and whole bird analyses are presented and criteria for establishing cause of death are discussed. Most of the DDT had been converted to DDE and DDD, and residues were found in all organs analyzed. Robin mortality was reduced, but not eliminated following Methoxychlor application in 1964; these losses were believed caused by residual DDT in the soil. There was no evidence DDT poisoning among other species in 1964, though the dead birds collected were not analyzed.

  12. The 2015 Dutch food-based dietary guidelines.

    PubMed

    Kromhout, D; Spaaij, C J K; de Goede, J; Weggemans, R M

    2016-08-01

    The objective of this study was to derive food-based dietary guidelines for the Dutch population. The dietary guidelines are based on 29 systematic reviews of English language meta-analyses in PubMed summarizing randomized controlled trials and prospective cohort studies on nutrients, foods and food patterns and the risk of 10 major chronic diseases: coronary heart disease, stroke, heart failure, diabetes, breast cancer, colorectal cancer, lung cancer, chronic obstructive pulmonary disease, dementia and depression. The committee also selected three causal risk factors for cardiovascular diseases or diabetes: systolic blood pressure, low-density lipoprotein cholesterol and body weight. Findings were categorized as strong or weak evidence, inconsistent effects, too little evidence or effect unlikely for experimental and observational data separately. Next, the committee selected only findings with a strong level of evidence for deriving the guidelines. Convincing evidence was based on strong evidence from the experimental data either or not in combination with strong evidence from prospective cohort studies. Plausible evidence was based on strong evidence from prospective cohort studies only. A general guideline to eat a more plant food-based dietary pattern and limit consumption of animal-based food and 15 specific guidelines have been formulated. There are 10 new guidelines on legumes, nuts, meat, dairy produce, cereal products, fats and oils, tea, coffee and sugar-containing beverages. Three guidelines on vegetables, fruits, fish and alcoholic beverages have been sharpened, and the 2006 guideline on salt stayed the same. A separate guideline has been formulated on nutrient supplements. Completely food-based dietary guidelines can be derived in a systematic and transparent way. PMID:27049034

  13. Molecular genetic analysis of six Dutch families with atrial fibrillation

    PubMed Central

    Entius, M.M.; Groenewegen, A.; Pronk, A.; van der Smagt, J.J; Loh, P.; Hauer, R.N.; Derksen, R.; van Gelder, I.C.; Lok, D.J.A.; Doevendans, P.A.

    2005-01-01

    Background Atrial fibrillation (AF), the most common cardiac arrhythmia, is characterised by rapid and irregular contraction of the atrium. The risk of AF increases with age and AF increases the risk of various heart disorders, stroke and mortality. AF can occur in a sporadic or familial form. The underlying mechanism leading to AF is not well known but genetic analysis can increase our insight into the molecular pathways in AF. Detailed information on the molecular mechanisms of a disorder increase options for diagnosis and treatment. Recently, a gain-of-function mutation in exon of the KCNQ1 gene located on chromosome 11 was identified in a large Chinese AF family. KCNQ1 associates with KCNE1 or KCNE2 (both located on chromosome 21) to form cardiac potassium channels. Subsequent analysis of Chinese families showed a KCNE2 mutation in two families. Other genetic studies show linkage to chromosome 6 and 10, indicating genetic heterogeneity. A number of studies have shown that altered expression of the atrial connexin40 protein is a risk factor for AF. Connexin genes encode gap-junction proteins that are important in cardiac conduction and for normal wave propagation. Objectives/methods In this study we analysed the role of KCNQ1, KCNE1 coding region and Cx40 promoter region in six Dutch AF families by sequence analysis. Conclusion No mutations were found in these genes. The absence of mutations indicates genetic heterogeneity in familial AF; however, further research is needed. Candidate genes are being sequenced, linkage analysis in a large family will be performed and additional AF families will be collected. ImagesFigure 1 PMID:25696507

  14. Feasibility of the Dutch ICF Activity Inventory: a pilot study

    PubMed Central

    2010-01-01

    Background Demographic ageing will lead to increasing pressure on visual rehabilitation services, which need to be efficiently organised in the near future. The Dutch ICF Activity Inventory (D-AI) was developed to assess the rehabilitation needs of visually impaired persons. This pilot study tests the feasibility of the D-AI using a computer-assisted telephone interview. Methods In addition to the regular intake, the first version of the D-AI was assessed in 20 patients. Subsequently, patients and intake assessors were asked to fill in an evaluation form. Based on these evaluations, a new version of the D-AI was developed. Results Mean administration time of the D-AI was 88.8 (± 41.0) minutes. Overall, patients and assessors were positive about the D-AI assessment. However, professionals and 60% of the patients found the administration time to be too long. All included items were considered relevant and only minor adjustments were recommended. Conclusion The systematic character of the revised D-AI will prevent topics from being overlooked and indicate which needs have the highest priority from a patient-centred perspective. Moreover, ongoing assessment of the D-AI will enhance evaluation of the rehabilitation process. To decrease administration time, in the revised D-AI only the top priority goals will be fully assessed. Using the D-AI, a rehabilitation plan based on individual needs can be developed for each patient. Moreover, it enables better evaluation of the effects of rehabilitation. A larger validation study is planned. PMID:21110871

  15. Return of separated children: the impact of Dutch policies.

    PubMed

    Kromhout, Mariska

    2011-01-01

    In many European countries, both the voluntary and the forced return of rejected asylum seekers are problematic. In the case of separated children, the difficulties seem to be even greater. In the Netherlands, many of these children disappear from the reception centres for unknown destinations, instead of returning to their home country. The new, stricter return policies adopted by the Dutch government in recent years have not (yet) changed this situation.In an explorative study of separated children aged between 15 and 18, the implementation and results of these policies were studied. The impact of the activities designed to promote voluntary return appeared to be very limited. Most separated young people did not want to consider return and did not take any action in this regard. Forced return rarely constituted a viable alternative. These findings may be explained by several factors. Among other things, considerations pertaining to personal security, family circumstances, and structural conditions in the countries of origin influence both the attitudes and behaviours of separated children, and host government policies. Moreover, many children were not willing to discuss their return with the youth care workers who were supposed to discuss and promote a voluntary return with them. The fact that most of the young people were allowed to stay in the reception centres until their eighteenth birthday enabled them to postpone making a final decision. A forced return was hindered by such obstacles as the absence of documents and the lack of appropriate care in the country of origin. More insight into the backgrounds of separated children and the (im)possibilities regarding their return seems necessary to be able to design more effective return policies. PMID:22167864

  16. Disability Management: Organizational Diversity and Dutch Employment Policy

    PubMed Central

    Haafkens, Joke A.

    2010-01-01

    Introduction While Human Resource Managers (HRM) and line managers could play a significant role in the prevention of job-related problems and in promotion of early job-continuation, it is not clear wether the chronically ill workers are recognized as a group. Unlike some other groups, distinguished by gender, age or ethnicity, those with chronic illness are less distinct and may not be included in diversity management programs. The aim of this research is to address theory and evidence in literature about the topic, as well as to inquire whether chronic illness of the employees is ‘visible’ in practice. Methods For desk research, we used a systematic search strategy involving medical, statistical, management, and social science databases (Web of Science, MedLine, Pub Med, Psych Info, etc.). Research results are based on case studies conducted with the managers and HRM of government and commercial organizations between March 2007 and October 2008 and between October 2008 and April 2009. These case studies were based on open interviews and focus group sessions (for human resource departments) which were consequently analyzed using thematical analysis. For group sessions, we used concept mapping to collect information from two groups of HRM professionals and managers. Secondary analysis included thematic and content analysis of ‘best practice’ organizations carried out by the Dutch organization Gatekeeper. Conclusions We have discovered that the chronically ill employees are largely invisible to HRM practitioners, line managers who do not always have the right instruments for implementation of the European or national frameworks. Most practitioners are unaware of the impact of chronic illness in their organizations and in employees work life. PMID:20383740

  17. Urban Climate Map System for Dutch spatial planning

    NASA Astrophysics Data System (ADS)

    Ren, Chao; Spit, Tejo; Lenzholzer, Sanda; Yim, Hung Lam Steve; Heusinkveld, Bert; van Hove, Bert; Chen, Liang; Kupski, Sebastian; Burghardt, René; Katzschner, Lutz

    2012-08-01

    Facing climate change and global warming, outdoor climatic environment is an important consideration factor for planners and policy makers because improving it can greatly contribute to achieve citizen's thermal comfort and create a better urban living quality for adaptation. Thus, the climatic information must be assessed systematically and applied strategically into the planning process. This paper presents a tool named Urban Climate Map System (UCMS) that has proven capable of helping compact cities to incorporate climate effects in planning processes in a systematic way. UCMS is developed and presented in a Geographic Information System (GIS) platform in which the lessons learned and experience gained from interdisciplinary studies can be included. The methodology of UCMS of compact cities, the construction procedure, and the basic input factors - including the natural climate resources and planning data - are described. Some literatures that shed light on the applicability of UMCS are reported. The Municipality of Arnhem is one of Dutch compact urban areas and still under fast urban development and urban renewal. There is an urgent need for local planners and policy makers to protect local climate and open landscape resources and make climate change adaptation in urban construction. Thus, Arnhem is chosen to carry out a case study of UCMS. Although it is the first work of Urban Climatic Mapping in The Netherlands, it serves as a useful climatic information platform to local planners and policy makers for their daily on-going works. We attempt to use a quick method to collect available climatic and planning data and create an information platform for planning use. It relies mostly on literature and theoretical understanding that has been well practiced elsewhere. The effort here is to synergize the established understanding for a case at hand and demonstrate how useful guidance can still be made for planners and policy makers.

  18. The Sooner the Better? An Investigation into the Role of Age of Onset and Its Relation with Transfer and Exposure in Bilingual Frisian-Dutch Children

    ERIC Educational Resources Information Center

    Blom, Elma; Bosma, Evelyn

    2016-01-01

    In this study, age of onset (AoO) was investigated in five- and six-year-old bilingual Frisian-Dutch children. AoO to Dutch ranged between zero and four and had a positive effect on Dutch receptive vocabulary size, but hardly influenced the children's accurate use of Dutch inflection. The influence of AoO on vocabulary was more prominent than the…

  19. Teaching polymers to fold

    SciTech Connect

    Judson, R.S. )

    1992-12-10

    A new method is presented for predicting folding pathways of polymers. The folding pathway is described as a generic program or sequence of logical steps of such a form that a computer can carry them out to produce a folded structure. A genetic (GA) is used to learn specific sequences or folding pathways that carry a denatured conformation into a target final conformation. The method is demonstrated on a model 2-dimensional polymer for which the global energy minimum is known. The GA learns a program that will fold a denatured polymer into its global energy minimum conformation. 27 refs., 4 figs.

  20. Low Dielectric Polymers

    NASA Technical Reports Server (NTRS)

    Venumbaka, Sreenivasulu R.; Cassidy, Patrick E.

    2002-01-01

    This report summarizes results obtained from research funded through Research Cooperative Agreement No. NCC-1-01033-"Low Dielectric Polymers" (from 5/10/01 through 5/09/02). Results are reported in three of the proposed research areas (Tasks 1-3 in the original proposal): (1) Repeat and confirm the preparation and properties of the new alkyl-substituted PEK, 6HC17-PEK, (2) Prepare and evaluate polymers derived from a highly fluorinated monomer, and (3) Prepare and evaluate new silicon and/or fluorine-containing polymers expected to retain useful properties at low temperature.

  1. Soluble porphyrin polymers

    DOEpatents

    Gust, Jr., John Devens; Liddell, Paul Anthony

    2015-07-07

    Porphyrin polymers of Structure 1, where n is an integer (e.g., 1, 2, 3, 4, 5, or greater) ##STR00001## are synthesized by the method shown in FIGS. 2A and 2B. The porphyrin polymers of Structure 1 are soluble in organic solvents such as 2-MeTHF and the like, and can be synthesized in bulk (i.e., in processes other than electropolymerization). These porphyrin polymers have long excited state lifetimes, making the material suitable as an organic semiconductor for organic electronic devices including transistors and memories, as well as solar cells, sensors, light-emitting devices, and other opto-electronic devices.

  2. Piezoelectric and pyroelectric polymers

    SciTech Connect

    Davis, G.T.

    1995-12-01

    Many polar polymers can be made to exhibit piezoelectric and pyroelectric properties by permanently aligning their dipoles in an electric field. The largest response is found in semi-crystalline polymers which exhibit a polar crystal phase which is amenable to reorientation in an applied electric field. The properties of poly(vinylidenefluoride), copolymers of vinyl idenefluoride and trifluoroethylene, nylon 7 and nylon 11 are compared. Polarization distribution across the thickness of such polymer films are discussed and novel techniques for the construction of piezoelectric bimorphs from the above copolymers are presented.

  3. [Military veterinary services in the former Dutch East Indies 1849-1950].

    PubMed

    Steltenpool, Bas

    2008-01-01

    The former Dutch colony is a vast archipelago and Java was the center of the Dutch colonial authority. In the outlying districts this authority had lesser influence. The army had a double task, at the one hand the protection of Java against foreign aggression and on the other hand police actions in the outlying districts. As usual during the 19th century, the army used animals, principally horses, but elephants were also used for provisioning the remote districts. In the beginning the veterinary care was in the hands of empiricists, but in 1830 the first officer horsedoctor was active and little by little a military veterinary service was developed and well trained vets came to the colony They were at the basis of the development of; veternnary medicine in the Dutch East Indies. PMID:20642140

  4. [Mental illness in the former Dutch Indies--four psychiatric syndromes: amok, latah, koro and neurasthenia].

    PubMed

    Bartelsman, M; Eckhardt, P P

    2007-12-22

    --At the beginning of the 20th century Dutch psychiatrists in the former Dutch Indies encountered exotic psychiatric syndromes and variant expressions of psychopathological diseases that were also prevalent in Europe. --The amok and latah syndromes were reported relatively frequently and were considered typical endemic psychopathologies. Amok is an acute condition of insanity in which the affected individual, a man, attempts to kill others. Latah is a shock-like condition in which the affected individual, a woman, mimics the movements and sounds of those nearby against her will. --The koro syndrome is considered a typical but rare psychosis seen primarily among the Chinese population of the former Dutch Indies. Patients have a recurring fear of the penis retracting into the body. --A diagnosis of 'tropical neurasthenia' was frequently made in Europeans for what today would be referred to as dysthymic disorder or minor depressive disorder. PMID:18237055

  5. [Willem Kouwenaar, editor-in-chief of the Dutch Journal of Medicine 1950-1954].

    PubMed

    van 't Hof, S E

    2007-12-15

    Willem Kouwenaar (1891-1954) spent the first part of his career in the Dutch East Indies as a physician of tropical medicine and tropical hygienist. He conducted many comparative epidemiological studies. After returning to The Netherlands in 1946, he became a professor of tropical medicine. Among other accomplishments, he developed a vaccine against yellow fever. In 1950 he became editor-in-chief of the Nederlandsch Tijdschrift voor Geneeskunde (Dutch Journal ofMedicine). He was of the opinion that 'everything that Dutch physicians are dealing with should also be presented for the information of the subscribers to our Journal,' which also applied to the controversial topics of birth control and contraceptive agents. He died in an airplane accident in 1954. PMID:18232201

  6. The Dutch Linguistic Intraoperative Protocol: a valid linguistic approach to awake brain surgery.

    PubMed

    De Witte, E; Satoer, D; Robert, E; Colle, H; Verheyen, S; Visch-Brink, E; Mariën, P

    2015-01-01

    Intraoperative direct electrical stimulation (DES) is increasingly used in patients operated on for tumours in eloquent areas. Although a positive impact of DES on postoperative linguistic outcome is generally advocated, information about the neurolinguistic methods applied in awake surgery is scarce. We developed for the first time a standardised Dutch linguistic test battery (measuring phonology, semantics, syntax) to reliably identify the critical language zones in detail. A normative study was carried out in a control group of 250 native Dutch-speaking healthy adults. In addition, the clinical application of the Dutch Linguistic Intraoperative Protocol (DuLIP) was demonstrated by means of anatomo-functional models and five case studies. A set of DuLIP tests was selected for each patient depending on the tumour location and degree of linguistic impairment. DuLIP is a valid test battery for pre-, intraoperative and postoperative language testing and facilitates intraoperative mapping of eloquent language regions that are variably located. PMID:25526520

  7. Anatomist on the dissecting table? Dutch anatomical professionals' views on body donation.

    PubMed

    Bolt, Sophie; Venbrux, Eric; Eisinga, Rob; Gerrits, Peter O

    2012-03-01

    Anatomical professionals know better than anyone else that donated bodies are a valuable asset to anatomical science and medical education. They highly value voluntary donations, since a dearth of bodies negatively affects their profession. With this in mind, we conducted a survey (n = 54) at the 171st scientific meeting of the Dutch Anatomical Society in 2009 to see to what extent anatomical professionals are willing to donate their own body. The results reveal that none of the survey participants are registered as a whole body donor and that only a quarter of them would consider the possibility of body donation. We argue that the two main constraints preventing Dutch anatomical professionals from donating their own body are their professional and their social environments. In contrast to the absence of registered body donors, half of the anatomical professionals are registered as an organ donor. This figure far exceeds the proportion of registered organ donors among the general Dutch population. PMID:21748808

  8. Acquiring a New Second Language Contrast: An Analysis of the English Laryngeal System of Native Speakers of Dutch

    ERIC Educational Resources Information Center

    Simon, Ellen

    2009-01-01

    This study examines the acquisition of the English laryngeal system by native speakers of (Belgian) Dutch. Both languages have a two-way laryngeal system, but while Dutch contrasts prevoiced with short-lag stops, English has a contrast between short-lag and long-lag stops. The primary aim of the article is to test two hypotheses on the acquisition…

  9. Government, School Autonomy, and Legitimacy: Why the Dutch Government Is Adopting an Unprecedented Level of Interference with Independent Schools

    ERIC Educational Resources Information Center

    Waslander, Sietske

    2010-01-01

    When looking at independent schools, the Netherlands is often mentioned as a prime example of school autonomy. Rooted in the constitution, the Dutch education system is build upon a combination of public funding and private operation. After almost a century of independent schools, the Dutch Government adopted a law recently which enables…

  10. The Dutch Schools of New Netherland and Colonial New York. Bulletin, 1912, No. 12. Whole Number 483

    ERIC Educational Resources Information Center

    Kilpatrick, William Heard

    1912-01-01

    The scope of this work has been indicated through the title. There were in New Netherland both Dutch and English settlements; the schools of the former only are included in the study. For a long time after the English took over the colony, the Dutch clung to their language and customs. The effort herein made is to trace the history of these Dutch…

  11. The Selection of Intonation Contours by Chinese L2 Speakers of Dutch: Orthographic Closure vs. Prosodic Knowledge

    ERIC Educational Resources Information Center

    He, Xuliang; van Heuven, Vincent J.; Gussenhoven, Carlos

    2012-01-01

    Chinese learners of Dutch and a control group of native speakers of Dutch were presented with 26 sentences in the order they come in a story, visually as well as auditorily as spoken with four intonation contours. Participants were instructed to select the most appropriate intonation contour for each sentence in a forced choice task. Chinese…

  12. Making Dutch Pupils Media Conscious: Preadolescents' Self-Assessment of Possible Media Risks and the Need for Media Education

    ERIC Educational Resources Information Center

    Kuter-Luks, Theresa; Heuvelman, Ard; Peters, Oscar

    2011-01-01

    Despite clear European and Dutch policies about media education, there is currently no media education curriculum in Dutch schools. A survey among preadolescents (n = 257) in six primary schools in the Netherlands included questions regarding media access, fears, risks, parental mediation of television and the internet, and the need for media…

  13. Une mort tres douce: end-of-life decisions in France; reflections from a Dutch perspective.

    PubMed

    Haverkamp, Margje H; van Delden, Johannes J M

    2006-01-01

    This study considers the range of thinking about end-of-life decisions (ELD) in France from a Dutch point of view, taking a small number of interviews with important French opinion-leaders as a basis. Until today, end-of-life care in France has been clouded with uncertainty pending the enactment of more specific definitions and regulations. French physicians could face a dilemma in treating a dying patient, caught between an official ban on ELD and a professional obligation to treat cases individually. The practical consequence of this climate is a lack of accountability of the French physician towards colleagues and patients. Rationalistic, paternalistic, and religious traditions have been obstructive to the adoption of regulatory reforms. In November 2004, Parliament accepted a law proposal by which the practice of the withholding and withdrawal of life-saving therapies would become more transparent, which would diminish the physician's fear of legal persecution. This proposal was then converted into law by the Senate. In the Netherlands, euthanasia - the active termination of life - is legal and regulated according to specific criteria. The Dutch approach has been shaped by an Anglo-Saxon emphasis on individual autonomy, and conforms to a broad preference in Dutch society to disclose and regulate controversial activities rather than to tolerate them sub rosa. As the Dutch regulations have been enacted, reporting rates - but not euthanasia cases - have risen. Compliance with the criteria and doctor-patient communication have been high. The French vigilance of professional autonomy provides a valuable example to the Dutch. The Dutch, in return, offer the French concrete examples for ELD policy. PMID:16858623

  14. Equality or Equity, Player or Guardian? The Dutch Government and Its Role in Providing Access Opportunities for Government Sponsored International Secondary Education, 1979-2009

    ERIC Educational Resources Information Center

    Prickarts, Boris

    2010-01-01

    This article focuses on the Dutch government's International Baccalaureate (IB) Diploma Programme (DP) Pilot, allowing Dutch pre-university students to take part in the IB DP. Is it likely to create "equal", or rather "equitable", access opportunities for government-sponsored Dutch international secondary schools? The article advances the position…

  15. The psychiatrist as administrator: the career of W.F. Theunissen in the Dutch East Indies.

    PubMed

    Pols, Hans

    2012-01-01

    W. F. Theunissen (1882-1961) was a leading psychiatrist in the Dutch East Indies. He was the medical director of several large mental hospitals after which he became director of the Dutch East Indies Public Health Service. Theunissen was not known for his research into the causes of mental illness. Instead, he made his mark as an administrator greatly reducing the expenses of the Lawang mental hospital by expanding occupational therapy in new and innovative ways. His accomplishments earned him the position of director of the Indies Public Health Department, where he oversaw the decentralisation of health services and the development of public health initiatives. PMID:23066606

  16. [Population born in Indonesia or in the former Dutch East-Indies].

    PubMed

    Prins, C J

    1997-04-01

    "The number of persons born in Indonesia or in the former Dutch East Indies and residing in the Netherlands decreases every year. This is primarily caused by ageing. Moreover, immigration from Indonesia has been at a relatively low level for many years. About 178 thousand persons born in Indonesia or in the former Dutch East Indies were living in the Netherlands on 1 January 1996." Information is included on parents' nationality, length of time in the Netherlands, migration policy, and spatial distribution. (EXCERPT) PMID:12348139

  17. Animals inside. Anatomy, interiority and virtue in the early modern Dutch Republic.

    PubMed

    Knoeff, Rina

    2008-01-01

    People in the early modern period frequently gave accounts of little animals (such as worms, flies, slugs and even dogs) living and breeding inside their bodies. This article investigates descriptions of "animals inside" in the works of Dutch anatomist Frederik Ruysch. It links the occurrence of such animals to the fear of pile worms endangering Dutch dikes and houses, and thereby the safety of society. The animals embodied pain and discomfort and were often associated with immorality and sexuality. As powerful symbols of interior corruption, they served as tangible reminders of the corruption of individuals as well as of the nation. PMID:18664011

  18. Eutrophication, water management, and the functioning of dutch estuaries and coastal lagoons

    SciTech Connect

    Nienhuis, P.H. )

    1992-12-01

    A number of European rivers (especially the Rhine) have a prevailing influence on the nutrient cycling of most Dutch estuaries. Owing to the increased loading of the estuaries with nitrogen and phosphorous compounds, effects of eutrophication on the biological communities are most evident in the tidal Western Wadden Sea and in a nontidal brackish lagoon, Veerse Meer. Whether the relation between changed nutrient loadings and changed biomass and production of primary and secondary producers in the turbid tidal Dutch ecosystems should be considered as a causal relation is questionable. The very widespread practice of lagoon modification confuses the effects of nutrient loading. 29 refs., 7 figs., 2 tabs.

  19. Meeting report on the first Sino-Dutch symposium on oncology.

    PubMed

    Peppelenbosch, Maikel P

    2016-01-01

    On October 31, 2015, the first Sino-Dutch symposium on oncology was organized in Guangzhou (China). The symposium revealed similarities between Chinese and Dutch efforts to improve the care of tumor patients and to create enhanced insight into the nature of cancers. In particular, it became evident for some types of cancer that immunotherapy should focus on counteracting interleukin-17-associated immunity and targeting cancer stroma. Targeting specific cancer microenvironment and stroma also opens new therapeutic options, including the use of radio-active theranostics and live tumor imaging-guided surgeries. PMID:26983406

  20. Analysis of Synthetic Polymers.

    ERIC Educational Resources Information Center

    Smith, Charles G.; And Others

    1989-01-01

    Reviews techniques for the characterization and analysis of synthetic polymers, copolymers, and blends. Includes techniques for structure determination, separation, and quantitation of additives and residual monomers; determination of molecular weight; and the study of thermal properties including degradation mechanisms. (MVL)

  1. Polymer Literature for Classrooms.

    ERIC Educational Resources Information Center

    Kirshenbaum, Gerald S.

    1987-01-01

    Lists eight sources of technical information suitable for classroom use which deal with polymer materials. Provides the names and addresses of these societies and associations and describes the type of information each has available. (TW)

  2. Nanocomposites with Crystalline Polymers

    NASA Astrophysics Data System (ADS)

    Kumar, Sanat

    2015-03-01

    The creation of ordered (layered) biomimetic materials typically follows a series of steps: first mix nanoparticles with water, organize the NPs by ice templating, evaporate the ice and then back fill with metal or polymer. We propose a simple method exploiting the in situ self-assembly of a crystalline polymer in the presence of nanoparticles to facilitate this process, and provide a completely new pathway for the synthesis of biomimetic materials. A suite of complementary experimental tools are used in this analysis. In parallel, we are developing theoretical tools to a priori predict the morphologies adopted by semicrystalline polymers. The convergence of these novel experimental and theoretical developments in the venerable field of semicrystalline polymers could lead to new applications for this largest class of commercially relevant polymeric materials. With Jacques Jestin, Brian Benicewicz, Dan Zhao, Longxi Zhao

  3. Sulfonated polyphenylene polymers

    DOEpatents

    Cornelius, Christopher J.; Fujimoto, Cy H.; Hickner, Michael A.

    2007-11-27

    Improved sulfonated polyphenylene compositions, improved polymer electrolyte membranes and nanocomposites formed there from for use in fuel cells are described herein. The improved compositions, membranes and nanocomposites formed there from overcome limitations of Nafion.RTM. membranes.

  4. Driving magnetic colloidal polymers

    NASA Astrophysics Data System (ADS)

    Dempster, Joshua; Olvera de La Cruz, Monica

    Magnetic colloids are of growing interest for applications such as drug delivery and in vitro tissue growth. Recent experiments have synthesized 1D chains of magnetic colloids into permanent colloidal polymers. We study magnetic colloidal polymers theoretically and computationally under the influence of time-varying external fields and find a rich set of controllable, dynamic conformations. By iterating through a sequence of conformations, these polymers can perform mechanical functions. We discuss possible roles for these polymers beyond those considered for single colloids. This work was supported as part of the Center for Bio-Inspired Energy Science, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Basic Energy Sciences under Award # DE-SC0000989.

  5. Dendritic Polymers for Theranostics

    PubMed Central

    Ma, Yuan; Mou, Quanbing; Wang, Dali; Zhu, Xinyuan; Yan, Deyue

    2016-01-01

    Dendritic polymers are highly branched polymers with controllable structures, which possess a large population of terminal functional groups, low solution or melt viscosity, and good solubility. Their size, degree of branching and functionality can be adjusted and controlled through the synthetic procedures. These tunable structures correspond to application-related properties, such as biodegradability, biocompatibility, stimuli-responsiveness and self-assembly ability, which are the key points for theranostic applications, including chemotherapeutic theranostics, biotherapeutic theranostics, phototherapeutic theranostics, radiotherapeutic theranostics and combined therapeutic theranostics. Up to now, significant progress has been made for the dendritic polymers in solving some of the fundamental and technical questions toward their theranostic applications. In this review, we briefly summarize how to control the structures of dendritic polymers, the theranostics-related properties derived from their structures and their theranostics-related applications. PMID:27217829

  6. Polymers for acid thickening

    SciTech Connect

    Dixon, K.W.

    1980-09-30

    Acids, thickened with branched emulsion or suspension polymers of diallyldimethylammonium chloride are useful as oil well drilling and fracturing fluids for stimulating well production and in other applications, such as thickeners for cosmetics, paints, adhesives, textiles and printing inks.

  7. Electroactive polymers for sensing

    PubMed Central

    2016-01-01

    Electromechanical coupling in electroactive polymers (EAPs) has been widely applied for actuation and is also being increasingly investigated for sensing chemical and mechanical stimuli. EAPs are a unique class of materials, with low-moduli high-strain capabilities and the ability to conform to surfaces of different shapes. These features make them attractive for applications such as wearable sensors and interfacing with soft tissues. Here, we review the major types of EAPs and their sensing mechanisms. These are divided into two classes depending on the main type of charge carrier: ionic EAPs (such as conducting polymers and ionic polymer–metal composites) and electronic EAPs (such as dielectric elastomers, liquid-crystal polymers and piezoelectric polymers). This review is intended to serve as an introduction to the mechanisms of these materials and as a first step in material selection for both researchers and designers of flexible/bendable devices, biocompatible sensors or even robotic tactile sensing units. PMID:27499846

  8. Functional Supramolecular Polymers*

    PubMed Central

    Aida, T.; Meijer, E.W.; Stupp, S.I.

    2012-01-01

    Supramolecular polymers can be random and entangled coils with the mechanical properties of plastics and elastomers, but with great capacity for processability, recycling, and self-healing due to their reversible monomer-to-polymer transitions. At the other extreme, supramolecular polymers can be formed by self-assembly among designed subunits to yield shape-persistent and highly ordered filaments. The use of strong and directional interactions among molecular subunits can achieve not only rich dynamic behavior but also high degrees of internal order that are not known in ordinary polymers. They can resemble, for example, the ordered and dynamic one-dimensional supramolecular assemblies of the cell cytoskeleton, and possess useful biological and electronic functions. PMID:22344437

  9. Interpenetrations in polymer brushes

    NASA Astrophysics Data System (ADS)

    Chakrabarti, Amitabha; Nelson, Peter; Toral, Raúl

    1994-01-01

    We carry out Monte Carlo simulations in both lattice and off-lattice geometry, to study the configurational properties of a system of two polymer-coated plates. We compare our results with numerical and analytical self-consistent-field theories. For the short chain-lengths considered here, we find both compression and interpenetration of the polymer brushes as the plate separation is decreased, instead of the ``classical-limit'' picture of compression with no interpenetration.

  10. Cylodextrin Polymer Nitrate

    NASA Technical Reports Server (NTRS)

    Kosowski, Bernard; Ruebner, Anja; Statton, Gary; Robitelle, Danielle; Meyers, Curtis

    2000-01-01

    The development of the use of cyclodextrin nitrates as possible components of insensitive, high-energy energetics is outlined over a time period of 12 years. Four different types of cyclodextrin polymers were synthesized, nitrated, and evaluated regarding their potential use for the military and aerospace community. The synthesis of these novel cyclodextrin polymers and different nitration techniques are shown and the potential of these new materials is discussed.

  11. Polymer optical motherboard technology

    NASA Astrophysics Data System (ADS)

    Keil, N.; Yao, H.; Zawadzki, C.; Grote, N.; Schell, M.

    2008-02-01

    In this paper, different hybridly integrated optical devices including optical multiplexer/ demultiplexer and optical transceivers are described. The devices were made using polymer planar light wave circuit (P2LC) technology. Laser diodes, photodiodes, and thin-film filters have been integrated. Key issues involved in this technology, in particular the coupling between laser diodes and polymer waveguides, and between waveguides and photodiodes and also fibers are discussed.

  12. Rechargeable solid polymer electrolyte battery cell

    DOEpatents

    Skotheim, Terji

    1985-01-01

    A rechargeable battery cell comprising first and second electrodes sandwiching a solid polymer electrolyte comprising a layer of a polymer blend of a highly conductive polymer and a solid polymer electrolyte adjacent said polymer blend and a layer of dry solid polymer electrolyte adjacent said layer of polymer blend and said second electrode.

  13. Rapid Polymer Sequencer

    NASA Technical Reports Server (NTRS)

    Stolc, Viktor (Inventor); Brock, Matthew W (Inventor)

    2013-01-01

    Method and system for rapid and accurate determination of each of a sequence of unknown polymer components, such as nucleic acid components. A self-assembling monolayer of a selected substance is optionally provided on an interior surface of a pipette tip, and the interior surface is immersed in a selected liquid. A selected electrical field is impressed in a longitudinal direction, or in a transverse direction, in the tip region, a polymer sequence is passed through the tip region, and a change in an electrical current signal is measured as each polymer component passes through the tip region. Each of the measured changes in electrical current signals is compared with a database of reference electrical change signals, with each reference signal corresponding to an identified polymer component, to identify the unknown polymer component with a reference polymer component. The nanopore preferably has a pore inner diameter of no more than about 40 nm and is prepared by heating and pulling a very small section of a glass tubing.

  14. Selenium speciation and extractability in Dutch agricultural soils.

    PubMed

    Supriatin, Supriatin; Weng, Liping; Comans, Rob N J

    2015-11-01

    The study aimed to understand selenium (Se) speciation and extractability in Dutch agricultural soils. Top soil samples were taken from 42 grassland fields and 41 arable land fields in the Netherlands. Total Se contents measured in aqua regia were between 0.12 and 1.97 mg kg(-1) (on average 0.58 mg kg(-1)). Organic Se after NaOCl oxidation-extraction accounted for on average 82% of total Se, whereas inorganic selenite (selenate was not measurable) measured in ammonium oxalate extraction using HPLC-ICP-MS accounted for on average 5% of total Se. The predominance of organic Se in the soils is supported by the positive correlations between total Se (aqua regia) and total soil organic matter content, and Se and organic C content in all the other extractions performed in this study. The amount of Se extracted followed the order of aqua regia > 1 M NaOCl (pH8) > 0.1 M NaOH>ammonium oxalate (pH3) > hot water>0.43 M HNO3 > 0.01 M CaCl2. None of these extractions selectively extracts only inorganic Se, and relative to other extractions 0.43 M HNO3 extraction contains the lowest fraction of organic Se, followed by ammonium oxalate extraction. In the 0.1M NaOH extraction, the hydrophobic neutral (HON) fraction of soil organic matter is richer in Se than in the hydrophilic (Hy) and humic acid (HA) fractions. The organic matter extracted in 0.01 M CaCl2 and hot water is in general richer in Se compared to the organic matter extracted in 0.1M NaOH, and other extractions (HNO3, ammonium oxalate, NaOCl, and aqua regia). Although the extractability of Se follows to a large extent the extractability of soil organic carbon, there is several time variations in the Se to organic C ratios, reflecting the changes in composition of organic matter extracted. PMID:26093220

  15. Simulations of Polymer Translocation

    NASA Astrophysics Data System (ADS)

    Vocks, H.

    2008-07-01

    Transport of molecules across membranes is an essential mechanism for life processes. These molecules are often long, and the pores in the membranes are too narrow for the molecules to pass through as a single unit. In such circumstances, the molecules have to squeeze -- i.e., translocate -- themselves through the pores. DNA, RNA and proteins are such naturally occuring long molecules in a variety of biological processes. Understandably, the process of translocation has been an active topic of current research: not only because it is a cornerstone of many biological processes, but also due to its relevance for practical applications. Translocation is a complicated process in living organisms -- the presence of chaperone molecules, pH, chemical potential gradients, and assisting molecular motors strongly influence its dynamics. Consequently, the translocation process has been empirically studied in great variety in biological literature. Study of translocation as a biophysical process is more recent. Herein, the polymer is simplified to a sequentially connected string of N monomers as it passes through a narrow pore on a membrane. The quantities of interest are the typical time scale for the polymer to leave a confining cell (the ``escape of a polymer from a vesicle'' time scale), and the typical time scale the polymer spends in the pore (the ``dwell'' time scale) as a function of N and other parameters like membrane thickness, membrane adsorption, electrochemical potential gradient, etc. Our research is focused on computer simulations of translocation. Since our main interest is in the scaling properties, we use a highly simplified description of the translocation process. The polymer is described as a self-avoiding walk on a lattice, and its dynamics consists of single-monomer jumps from one lattice site to another neighboring one. Since we have a very efficient program to simulate such polymer dynamics, which we decribe in Chapter 2, we can perform long

  16. Precursor polymer compositions comprising polybenzimidazole

    SciTech Connect

    Klaehn, John R.; Peterson, Eric S.; Orme, Christopher J.

    2015-07-14

    Stable, high performance polymer compositions including polybenzimidazole (PBI) and a melamine-formaldehyde polymer, such as methylated, poly(melamine-co-formaldehyde), for forming structures such as films, fibers and bulky structures. The polymer compositions may be formed by combining polybenzimidazole with the melamine-formaldehyde polymer to form a precursor. The polybenzimidazole may be reacted and/or intertwined with the melamine-formaldehyde polymer to form the polymer composition. For example, a stable, free-standing film having a thickness of, for example, between about 5 .mu.m and about 30 .mu.m may be formed from the polymer composition. Such films may be used as gas separation membranes and may be submerged into water for extended periods without crazing and cracking. The polymer composition may also be used as a coating on substrates, such as metal and ceramics, or may be used for spinning fibers. Precursors for forming such polymer compositions are also disclosed.

  17. Processing Trade-Offs in the Reading of Dutch Derived Words

    ERIC Educational Resources Information Center

    Kuperman, Victor; Bertram, Raymond; Baayen, R. Harald

    2010-01-01

    This eye-tracking study explores visual recognition of Dutch suffixed words (e.g., "plaats+ing" "placing") embedded in sentential contexts, and provides new evidence on the interplay between storage and computation in morphological processing. We show that suffix length crucially moderates the use of morphological properties. In words with shorter…

  18. "Ground Force" Does the Dutch Higher Education Gardens: Three Scenarios Revisited

    ERIC Educational Resources Information Center

    Westerheijden, Don F.; Huisman, Jeroen; de Boer, Harry

    2004-01-01

    This article shows the changes currently made to higher education in the Netherlands, and what they may mean for its future. Findings from a Delphi study were used to develop three scenarios for Dutch higher education in 2010. The Palatial Garden scenario combined little openness of the system with high governmental involvement, making it more…

  19. The Perception of Participation in Executive Governance Structures in Dutch Universities

    ERIC Educational Resources Information Center

    Huisman, Jeroen; de Boer, Harry; Goedegebuure, Leo

    2006-01-01

    In 1997 a new governance act, based on the principles of New Public Management (NPM) was introduced at Dutch universities. The aims were to realise integrated management, to strengthen the position of executives at the central (executive board) and faculty (dean) levels, to introduce a Supervisory Board at the institution's central level, and to…

  20. Towards a Further Characterization of Phonological and Literacy Problems in Dutch-Speaking Children with Dyslexia

    ERIC Educational Resources Information Center

    Boets, Bart; De Smedt, Bert; Cleuren, Leen; Vandewalle, Ellen; Wouters, Jan; Ghesquiere, Pol

    2010-01-01

    This longitudinal study examined the development of phonology and literacy in Dutch-speaking children at family risk of dyslexia and in matched controls. Measures were administered in kindergarten (before the start of formal reading instruction), in first and in third grade. Children, diagnosed with dyslexia in third grade, showed impaired…

  1. Morphological Awareness and Early and Advanced Word Recognition and Spelling in Dutch

    ERIC Educational Resources Information Center

    Rispens, Judith E.; McBride-Chang, Catherine; Reitsma, Pieter

    2008-01-01

    This study investigated the relations of three aspects of morphological awareness to word recognition and spelling skills of Dutch speaking children. Tasks of inflectional and derivational morphology and lexical compounding, as well as measures of phonological awareness, vocabulary and mathematics were administered to 104 first graders (mean age 6…

  2. On the Syntax-Semantics Interface in Dutch: Adult and Child L2 Acquisition Compared

    ERIC Educational Resources Information Center

    Unsworth, Sharon

    2004-01-01

    Using experimental data from adult and child non-native language acquirers (L2ers), this paper addresses "interface issues" in language acquisition in two different ways. First, it examines the acquisition of direct object scrambling in Dutch, a phenomenon which involves the interaction of at least two different modules of language, i.e., syntax…

  3. Gendered Subjective Theologies: Dutch Teenage Girls and Boys on the Role of Religion in Their Life

    ERIC Educational Resources Information Center

    ter Avest, Ina; Jozsa, Dan-Paul; Knauth, Thorsten

    2010-01-01

    In this article about the Dutch contribution to the REDCo sub-project on the role of gender, related to religion in/and school, the authors present the characteristics in the answers girls and boys, respectively gave to their questionnaires. Qualitative as well as quantitative methods were used in this research project. The research findings show…

  4. Timing Preferences for Women's Family-Life Transitions: Intergenerational Transmission among Migrants and Dutch

    ERIC Educational Resources Information Center

    de Valk, Helga A. G.; Liefbroer, Aart C.

    2007-01-01

    This study examines the transmission of preferences regarding the timing of family-life transitions of women among migrant and native Dutch families. We study how and to what extent parental preferences, migrant origin, and family characteristics affect the child's timing preferences. We use parent and child data (N = 1,290) from the Netherlands…

  5. Quality of Austrian and Dutch Falls-Prevention Information: A Comparative Descriptive Study

    ERIC Educational Resources Information Center

    Schoberer, Daniela; Mijnarends, Donja M.; Fliedner, Monica; Halfens, Ruud J. G.; Lohrmann, Christa

    2016-01-01

    Objectives: The aim of this study was to evaluate and compare the quality of written patient information material available in Austrian and Dutch hospitals and nursing homes pertaining to falls prevention. Design: Comparative descriptive study design Setting: Hospitals and nursing homes in Austria and the Netherlands. Method: Written patient…

  6. Teachers' Professional Development: An Analysis of the Use of Professional Development Plans in a Dutch School

    ERIC Educational Resources Information Center

    Janssen, S.; Kreijns, K.; Bastiaens, T.; Stijnen, S.; Vermeulen, M.

    2012-01-01

    Professional development of teachers has become an essential condition in today's knowledge-based society to sustain the quality of teaching. Therefore, the Dutch government promotes this professional development. As a result, Professional Development Plans (PDPs) are now increasingly used to stimulate and support the professional development of…

  7. Factors of Success and Failure in the Acquisition of Grammatical Gender in Dutch

    ERIC Educational Resources Information Center

    Cornips, Leonie; Hulk, Aafke

    2008-01-01

    The goal of this article is to examine the factors that are proposed in the literature to explain the success--failure in the child L2 (second language) acquisition of grammatical gender in Dutch definite determiners. Focusing on four different groups of bilingual children, we discuss four external success factors put forward in the literature:…

  8. Perception of Individualism and Collectivism in Dutch Society: A Developmental Approach

    ERIC Educational Resources Information Center

    Oppenheimer, Louis

    2004-01-01

    Within Triandis's (1994) theoretical framework, two studies are reported that deal with the developmental course for subjective perceptions of cultural dimensions in Dutch society (i.e., vertical and horizontal individualism and collectivism). While perceptions of society are always subjectively determined, the perceived dimensions that are…

  9. PCL-R Psychopathy Predicts Disruptive Behavior Among Male Offenders in a Dutch Forensic Psychiatric Hospital

    ERIC Educational Resources Information Center

    Hildebrand, Martin; De Ruiter, Corine; Nijman, Henk

    2004-01-01

    In this study, the relationship between psychopathy, according to the Dutch language version of Hare's Psychopathy Checklist-Revised (PCL-R), and various types of disruptive behavior during inpatient forensic psychiatric treatment is investigated. Ninety-two male participants were administered the PCL-R following admission to an inpatient forensic…

  10. The Complexities of a Lesson Study in a Dutch Situation: Mathematics Teacher Learning

    ERIC Educational Resources Information Center

    Verhoef, Nellie; Tall, David; Coenders, Fer; van Smaalen, Daan

    2014-01-01

    This study combines the Japanese lesson study approach and mathematics teachers' professional development. The first year of a 4-year project in which 3 Dutch secondary school teachers worked cooperatively on introducing making sense of the calculus is reported. The analysis focusses on instrumental and relational student understanding of…

  11. Parental Work Demands and Parent-Child, Family, and Couple Leisure in Dutch Families: What Gives?

    ERIC Educational Resources Information Center

    Roeters, Anne; Treas, Judith K.

    2011-01-01

    This study uses data on 898 Dutch couples with minor children to examine whether parental work demands are related differently to one-on-one parent-child, family, and couple leisure activities. The authors presume that the impact of working hours and work arrangements is smaller on activities that are prioritized highly and that are easier and…

  12. Dutch and English toddlers' use of linguistic cues in predicting upcoming turn transitions

    PubMed Central

    Lammertink, Imme; Casillas, Marisa; Benders, Titia; Post, Brechtje; Fikkert, Paula

    2015-01-01

    Adults achieve successful coordination during conversation by using prosodic and lexicosyntactic cues to predict upcoming changes in speakership. We examined the relative weight of these linguistic cues in the prediction of upcoming turn structure by toddlers learning Dutch (Experiment 1; N = 21) and British English (Experiment 2; N = 20) and adult control participants (Dutch: N = 16; English: N = 20). We tracked participants' anticipatory eye movements as they watched videos of dyadic puppet conversation. We controlled the prosodic and lexicosyntactic cues to turn completion for a subset of the utterances in each conversation to create four types of target utterances (fully incomplete, incomplete syntax, incomplete prosody, and fully complete). All participants (Dutch and English toddlers and adults) used both prosodic and lexicosyntactic cues to anticipate upcoming speaker changes, but weighed lexicosyntactic cues over prosodic ones when the two were pitted against each other. The results suggest that Dutch and English toddlers are already nearly adult-like in their use of prosodic and lexicosyntactic cues in anticipating upcoming turn transitions. PMID:25964772

  13. The Resilience of Recently Graduated and Unemployed Dutch Academics in Coping with the Economic Crisis

    ERIC Educational Resources Information Center

    Dekker, Jeroen J. H.; Amsing, Hilda T. A.; Hahurij, Lisa; Wichgers, Inge

    2014-01-01

    Some years after the world-wide crisis starting in 2008, also many recently graduated Dutch academics were confronted with the problem of how to cope with getting a job. This article focuses on the coping strategies they use when searching after a job, spending the day, and coping with limited financial means. 91 graduated academics completed a…

  14. Scenarios for Dutch Teacher Education. A Trip to Rome: Coach Bus Company or Travel Agency?

    ERIC Educational Resources Information Center

    Snoek, Marco

    2003-01-01

    Stimulated by severe teacher shortages, teacher education in the Netherlands is changing toward competence-based, work- based-, and market-oriented programs. A Dutch scenario project was developed in which four scenarios for the future of teacher education emerged. These scenarios were structured by the freedom of schools to define the type of…

  15. The Role of Familiarity and Similarity in Friendship Relationships in Toddlers in Dutch Daycare Centers

    ERIC Educational Resources Information Center

    van Hoogdalem, Anne-Greth; Singer, Elly; Wijngaards, Leoniek; Heesbeen, Danielle

    2012-01-01

    In this article a study is presented of selective affiliation of two- and three-year-old children in the natural situation of Dutch daycare centers. Data of (behavioral) characteristics of 674 pairs of children (dyads) were collected. Multi-level analyses of these dyadic data were conducted and showed that the chance of friendship between two…

  16. Mental Health Problems of Dutch Youth with Hearing Loss as Shown on the Youth Self Report

    ERIC Educational Resources Information Center

    Van Eldik, Theo

    2005-01-01

    The prevalence of mental health problems among youth with hearing loss was assessed with an adjusted version of the Dutch rendition of the Youth Self Report, or YSR (Achenbach, 1991). The sample totaled 202 youth, aged 11?18 years, with auditory disabilities. The prevalence rates of externalizing problems, internalizing problems, and moderate to…

  17. The Evaluation of Phonological vs. Phonetic Variation in Dutch Standard Pronunciation.

    ERIC Educational Resources Information Center

    Knops, Uus

    There is a substantial discrepancy between normative and empirical views on Dutch standard pronunciation. The discrepancy between these views can be reduced by looking at the empirical range as being structured from an imagined point of reference. The prescriptive standard then operates as the ultimate model toward which the submodels for standard…

  18. Past Tense Productivity in Dutch Children with and without SLI: The Role of Morphophonology and Frequency

    ERIC Educational Resources Information Center

    Rispens, Judith E.; De Bree, Elise H.

    2014-01-01

    This study focuses on morphophonology and frequency in past tense production. It was assessed whether Dutch five- and seven-year-old typically developing (TD) children and eight-year-old children with specific language impairment (SLI) produce the correct allomorph in regular, irregular, and novel past tense formation. Type frequency of the…

  19. News Note: SA-Dutch SKA data science partnership seeks to address big data conundrum

    NASA Astrophysics Data System (ADS)

    2015-12-01

    The visit to South Africa by Netherlands Prime Minister Mark Rutte included a pivotal South African-Dutch data science partnership between key institutions from both countries bringing us closer to understanding the volume of data generated by the Square Kilometre Array (SKA).

  20. Pre-Conditions, Benefits and Costs of Privatized Public Services: Lessons from the Dutch Educational System.

    ERIC Educational Resources Information Center

    James, Estelle

    The system in the Netherlands of "privatization," a government policy of financially supporting private schools and encouraging people to use them, depends on conditions in Dutch society that are conducive to a large nongovernment, nonprofit sector. These include cultural heterogeneity, coupled with the lack of a single dominant culture and class…

  1. Harbor porpoise Phocoena phocoena strandings on the Dutch coast: No genetic structure, but evidence of inbreeding

    NASA Astrophysics Data System (ADS)

    van der Plas-Duivesteijn, Suzanne J.; Smit, Femmie J. L.; van Alphen, Jacques J. M.; Kraaijeveld, Ken

    2015-03-01

    Conservation management in the North Sea is often motivated by the population size of marine mammals, like harbor porpoises Phocoena phocoena. In the Dutch part of the North Sea, sighting and stranding data are used to estimate population sizes, but these data give little insight into genetic structuring of the population. In this study we investigated genetic structure among animals stranded at different locations and times of year. We also tested whether there is a link between stranding and necropsy data, and genetic diversity. We made use of both mitochondrial (mtDNA) and microsatellite DNA analysis of samples from dead stranded porpoises along the Dutch coast during 2007. mtDNA analysis showed 6 variable positions in the control region, defining 3 different haplotypes. mtDNA haplotypes were not randomly distributed along the Dutch coastline. However, microsatellite analysis showed that these mtDNA haplotypes did not represent separate groups on a nuclear level. Furthermore, microsatellite analysis revealed no genotypic differences between seasons, locations or genders. The results of this study indicate that the Dutch population is panmictic. In contrast, heterozygosity levels were low, indicating some level of inbreeding in this population. However, this was not corroborated by other indices of inbreeding. This research provided insight into genetic structuring of stranded porpoises in 2007, but data from multiple years should be included to be able to help estimate population sizes.

  2. What Makes Children Behave Aggressively? The Inner Logic of Dutch Children in Special Education

    ERIC Educational Resources Information Center

    Visser, Marieke; Singer, Elly; van Geert, Paul L. C.; Kunnen, Saskia E.

    2009-01-01

    The ambiguous results of existing intervention programmes show the need for new ways in research on aggression among children. The present study focuses on the children's own perspective on their aggressive behaviour. Based on a constructivist approach, the inner logic of narratives about peer conflicts of 64 children in Dutch special education…

  3. Dutch Adolescents' Tolerance of Practices by Muslim Actors: The Effect of Issue Framing

    ERIC Educational Resources Information Center

    Gieling, Maike; Thijs, Jochem; Verkuyten, Maykel

    2012-01-01

    This research, conducted in the Netherlands, examines whether native adolescents' tolerance of practices by Muslim immigrants (e.g., the founding of Islamic schools) is affected by the type of considerations (e.g., educational freedom vs. integration of Muslims in Dutch society). Using an experimental questionnaire design (N = 970), the findings…

  4. Multiple Identities and Religious Transmission: A Study among Moroccan-Dutch Muslim Adolescents and Their Parents

    ERIC Educational Resources Information Center

    Verkuyten, Maykel; Thijs, Jochem; Stevens, Gonneke

    2012-01-01

    This study investigates the relation between religious group identification and ethnic and national identity among Moroccan-Dutch Muslim adolescents (11-18 years) and their parents (n = 369). Compared to their parents, adolescents showed higher national identification and lower religious and ethnic group identification. However, for adolescents…

  5. When Will I Succeed in My First-Year Diploma? Survival Analysis in Dutch Higher Education

    ERIC Educational Resources Information Center

    Bruinsma, Marjon; Jansen, Ellen P. W. A.

    2009-01-01

    The goal of this study was to illustrate survival analysis with higher education data and gain insight into a limited set of factors that predict when students passed their first-year examination at a Dutch university. Study participants consisted of 565 first-year students in four departments. Data were collected on when students pass their…

  6. Hereditary Deafness in a Former Fishing Village on the Dutch Coast

    ERIC Educational Resources Information Center

    Nyst, Victoria A. S.

    2016-01-01

    In communities with an increased prevalence of hereditary deafness, social, and linguistic adaptations are found in response. Aulbers (1959) describes a high prevalence of deafness in a fishing village on the Dutch coast: Katwijk aan Zee. This article aims to assess the current prevalence of deafness in Katwijk, as well as the current sign…

  7. Art Education in the Former Dutch East Indies in the 1930s: Questions of Different Cultures.

    ERIC Educational Resources Information Center

    Van Rheeden, Herbert

    1990-01-01

    Analyzes drawings by children from a Dutch East Indies exhibition in 1937 organized by educator Johan Toot. Divides the drawings thematically and discusses how the drawings are influenced by various cultures. Describes how Johan Toot worked to replace rote learning with an activity-based education. (KM)

  8. Factoring out the Parallelism Effect in VP-Ellipsis: English vs. Dutch Contrasts

    ERIC Educational Resources Information Center

    Duffield, Nigel; Matsuo, Ayumi; Roberts, Leah

    2009-01-01

    Previous studies, including Duffield and Matsuo (2001; 2002; 2009), have demonstrated second language learners' overall sensitivity to a parallelism constraint governing English VP-ellipsis constructions: like native speakers (NS), advanced Dutch, Spanish and Japanese learners of English reliably prefer ellipsis clauses with structurally parallel…

  9. Happy Spouses, Happy Parents? Family Relationships among Finnish and Dutch Dual Earners

    ERIC Educational Resources Information Center

    Malinen, Kaisa; Kinnunen, Ulla; Tolvanen, Asko; Ronka, Anna; Wierda-Boer, Hilde; Gerris, Jan

    2010-01-01

    In this study links between spousal and parent-child relationships among Finnish (n = 157 couples) and Dutch (n = 276 couples) dual earners with young children were examined using paired questionnaire data. Variable-oriented analyses (structural equation modeling with a multigroup procedure) supported the spillover hypothesis, as higher levels of…

  10. Reading Polymorphemic Dutch Compounds: Toward a Multiple Route Model of Lexical Processing

    ERIC Educational Resources Information Center

    Kuperman, Victor; Schreuder, Robert; Bertram, Raymond; Baayen, R. Harald

    2009-01-01

    This article reports an eye-tracking experiment with 2,500 polymorphemic Dutch compounds presented in isolation for visual lexical decision while readers' eye movements were registered. The authors found evidence that both full forms of compounds ("dishwasher") and their constituent morphemes (e.g., "dish," "washer," "er") and morphological…

  11. Meaning and Function of Dummy Auxiliaries in Adult Acquisition of Dutch as an Additional Language

    ERIC Educational Resources Information Center

    Julien, Manuela; van Hout, Roeland; van de Craats, Ineke

    2016-01-01

    This article presents the results of experimental data on language production and comprehension. These show that adult learners of Dutch as an additional language, with different language backgrounds, and a L2 proficiency below level A2 (Waystage) of the Common European Framework of Reference for Languages (CEFR; Council of Europe, 2001), use…

  12. Characteristics of Stuttering-Like Disfluencies in Dutch-Speaking Children

    ERIC Educational Resources Information Center

    Boey, Ronny A.; Wuyts, Floris L.; Van de Heyning, Paul H.; De Bodt, Marc S.; Heylen, Louis

    2007-01-01

    The purpose of this study was to compare the characteristics of stuttering-like disfluencies in a group of native Dutch-speaking children who stutter (n = 693), with a group of normally fluent children (n = 79). Methods involved the observation of stuttering-like disfluencies in participants' conversational speech samples (total 77,200 words),…

  13. The Dutch Review Process for Evaluating the Quality of Psychological Tests: History, Procedure, and Results

    ERIC Educational Resources Information Center

    Evers, Arne; Sijtsma, Klaas; Lucassen, Wouter; Meijer, Rob R.

    2010-01-01

    This article describes the 2009 revision of the Dutch Rating System for Test Quality and presents the results of test ratings from almost 30 years. The rating system evaluates the quality of a test on seven criteria: theoretical basis, quality of the testing materials, comprehensiveness of the manual, norms, reliability, construct validity, and…

  14. Sleep habits and sleep disturbances in Dutch children: a population-based study

    PubMed Central

    Waumans, Ruth C.; van den Berg, Gerrit; Gemke, Reinoud J. B. J.

    2010-01-01

    Sleep disorders can lead to significant morbidity. Information on sleep in healthy children is necessary to evaluate sleep disorders in clinical practice, but data from different societies cannot be simply generalized. The aims of this study were to (1) assess the prevalence of sleep disturbances in Dutch healthy children, (2) describe sleep habits and problems in this population, (3) collect Dutch norm data for future reference, and (4) compare sleep in children from different cultural backgrounds. A population-based descriptive study was conducted using the Children’s sleep habits questionnaire and the sleep self-report. One thousand five hundred seven proxy-reports and 262 self-reports were analyzed. Mean age was 8.5 years (95% confidence interval, 8.4–8.6), 52% were boys. Sleep problems in Dutch children were present in 25%, i.e., comparable to other populations. Sleep habits were age-related. Problem sleepers scored significantly higher on all scales. Correlations between parental and self-assessments were low to moderate. Dutch children had significantly more sleep disturbances than children from the USA and less than Chinese children. Cognitions and attitudes towards what is considered normal sleep seem to affect the appraisal of sleep, this probably accounts partly for cultural differences. For a better understanding of cultural influences on sleep, more information on these determinants and the establishment of cultural norms are mandatory. PMID:20191392

  15. Sign-Supported Dutch in Children with Severe Speech and Language Impairments: A Multiple Case Study

    ERIC Educational Resources Information Center

    Wijkamp, Inge; Gerritsen, Betsy; Bonder, Freke; Haisma, Hinke; van der Schans, Cees

    2010-01-01

    In the Netherlands, many educators and care providers working at special schools for children with severe speech and language impairments (SSLI) use sign-supported Dutch (SSD) to facilitate communication. Anecdotal experiences suggest positive results, but empirical evidence is lacking. In this multiple case study the changes that occur in the way…

  16. 75 FR 30299 - Drawbridge Operation Regulations; Newtown Creek, Dutch Kills, English Kills, and Their...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Newtown Creek, Dutch Kills, English Kills, and Their Tributaries, NY, Maintenance AGENCY: Coast Guard, DHS. ACTION: Notice of...

  17. 75 FR 62469 - Drawbridge Operation Regulations; Newtown Creek, Dutch Kills, English Kills, and Their...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Newtown Creek, Dutch Kills, English Kills, and Their Tributaries, NY, Maintenance AGENCY: Coast Guard, DHS. ACTION: Notice of...

  18. Health-hazard evaluation report HETA 86-005-1679, Dutch Girl Cleaners, Springdale, Ohio

    SciTech Connect

    Burr, G.A.; Todd, W.

    1986-03-01

    An environmental survey at Dutch Girl Cleaners in the Thriftway Mini Mall, Springdale, Ohio, was conducted on October 25, 1985, and air samples collected on October 30, 1985 from the cleaners, an adjacent supermarket and the enclosed pedestrian mall were analyzed for perchloroethylene.

  19. Modeling the Growth of Word-Decoding Skills: Evidence from Dutch

    ERIC Educational Resources Information Center

    Verhoeven, Ludo; van Leeuwe, Jan

    2009-01-01

    This study investigated the growth of word-decoding skills throughout the elementary school years for a representative sample of 2,819 Dutch children. Children's decoding abilities for (a) regular consonant-vowel-consonant words, (b) complex monosyllabic words with consonant clusters in prevocalic and postvocalic position, and (c) polysyllabic…

  20. Studying Dutch emigration to the United States: new methods and concepts.

    PubMed

    Swierenga, R P

    1984-01-01

    The author considers how modern computerized methods could be applied to the study of migration from the Netherlands to the United States. An example is presented using data on Dutch migration from 1835 to 1880. The sources of available data in the Netherlands and the United States are reviewed. PMID:12267139

  1. A Dutch Comprehension Test for Identifying Reading Problems in L1 and L2 Students.

    ERIC Educational Resources Information Center

    Hacquebord, Hilde

    1999-01-01

    Evaluates the Dutch Text Comprehension Test, developed to help improve the education of secondary school minority students in the Netherlands. Finds the test proved reliable for both L1 students and L2 students. Suggests, although classification results were not optimal, the test can be used for diagnostic purposes provided a relatively large…

  2. Qualitative Issues of Planning in a Dutch University. AIR 1985 Annual Forum Paper.

    ERIC Educational Resources Information Center

    Savenije, Bas; Otten, Christ

    Results of changes to the planning process at the University of Utrecht in the Netherlands are described. During the past years, government actions related to retrenchment prompted the Dutch universities to change their planning process in order to increase flexibility and to account for differences in quality. Two important procedures were…

  3. Parental Divorce and Offspring Depressive Symptoms: Dutch Developmental Trends during Early Adolescence

    ERIC Educational Resources Information Center

    Oldehinkel, Albertine J.; Ormel, Johan; Veenstra, Rene; De Winter, Andrea F.; Verhulst, Frank C.

    2008-01-01

    In this study, we investigated if the association between parental divorce and depressive symptoms changes during early adolescence and if developmental patterns are similar for boys and girls. Data were collected in a prospective population cohort of Dutch adolescents (N = 2,149), aged 10 - 15 years. Outcome variables were self-reported and…

  4. Development of Morphosyntactic Accuracy and Grammatical Complexity in Dutch School-Age Children with SLI

    ERIC Educational Resources Information Center

    Zwitserlood, Rob; van Weerdenburg, Marjolijn; Verhoeven, Ludo; Wijnen, Frank

    2015-01-01

    Purpose: The purpose of this study was to identify the development of morphosyntactic accuracy and grammatical complexity in Dutch school-age children with specific language impairment (SLI). Method: Morphosyntactic accuracy, the use of dummy auxiliaries, and complex syntax were assessed using a narrative task that was administered at three points…

  5. The Impact of Parental Religiosity on Parenting Goals and Parenting Style: A Dutch Perspective

    ERIC Educational Resources Information Center

    Vermeer, Paul

    2011-01-01

    Several studies, conducted mainly in the United States, have revealed that parental religiosity influences the way parents raise their children. Against this background, the current study explores if such an effect is also discernible in the Netherlands. Data were gathered as part of a longitudinal study, in which 356 Dutch parents answered…

  6. Innovative Constructions in Dutch Turkish: An Assessment of Ongoing Contact-Induced Change

    ERIC Educational Resources Information Center

    Dogruoz, A. Seza; Backus, Ad

    2009-01-01

    Turkish as spoken in the Netherlands (NL-Turkish) sounds "different" (unconventional) to Turkish speakers in Turkey (TR-Turkish). We claim that this is due to structural contact-induced change that is, however, located within specific lexically complex units copied from Dutch. This article investigates structural change in NL-Turkish through…

  7. Salience and Contrast Effects in Reference Resolution: The Interpretation of Dutch Pronouns and Demonstratives

    ERIC Educational Resources Information Center

    Kaiser, Elsi

    2011-01-01

    We report three experiments on reference resolution in Dutch. The results of two off-line experiments and an eye-tracking study suggest that the interpretation of different referential forms--in particular, "emphatic" strong pronouns, weak pronouns, and demonstrative pronouns--cannot be satisfactorily explained in terms of a single feature of the…

  8. Spelling Dutch Doublets: Children's Learning of a Phonological and Morphological Spelling Rule

    ERIC Educational Resources Information Center

    Notenboom, Annelise; Reitsma, Pieter

    2007-01-01

    This study addresses the question of why spellings determined by morphology are relatively hard to acquire by presenting a latent class model of children's acquisition of a doublet of consonants in the spelling of Dutch verbs. This spelling pattern can be determined either by a phonological rule (after a short vowel, a doublet is spelled) or a…

  9. Testing Structural Invariance of the Achievement Goal Questionnaire in American, Chinese, and Dutch College Students

    ERIC Educational Resources Information Center

    Sun, Huaping; Hernandez, Diley

    2012-01-01

    This study investigates the structural invariance of the Achievement Goal Questionnaire (AGQ) in American, Chinese, and Dutch college students. Using confirmatory factor analyses (CFA), the authors found evidence for the four-factor structure of achievement goals in all three samples. Subsequent multigroup CFAs supported structural invariance of…

  10. The Novaco Anger Scale--Provocation Inventory (1994 Version) in Dutch Forensic Psychiatric Patients

    ERIC Educational Resources Information Center

    Hornsveld, Ruud H. J.; Muris, Peter; Kraaimaat, Floris W.

    2011-01-01

    We examined the psychometric properties of the Novaco Anger Scale--Provocation Inventory (NAS-PI, 1994 version) in Dutch violent forensic psychiatric patients and secondary vocational students. A confirmatory factor analysis of the subscale structure of the NAS was carried out, reliability was investigated, and relations were calculated between…

  11. The benefits of being bilingual: working memory in bilingual Turkish-Dutch children.

    PubMed

    Blom, Elma; Küntay, Aylin C; Messer, Marielle; Verhagen, Josje; Leseman, Paul

    2014-12-01

    Whether bilingual children outperform monolingual children on visuospatial and verbal working memory tests was investigated. In addition, relations among bilingual proficiency, language use at home, and working memory were explored. The bilingual Turkish-Dutch children (n=68) in this study were raised in families with lower socioeconomic status (SES) and had smaller Dutch vocabularies than Dutch monolingual controls (n=52). Having these characteristics, they are part of an under-researched bilingual population. It was found that the bilingual Turkish-Dutch children showed cognitive gains in visuospatial and verbal working memory tests when SES and vocabulary were controlled, in particular on tests that require processing and not merely storage. These findings converge with recent studies that have revealed bilingual cognitive advantages beyond inhibition, and they support the hypothesis that experience with dual language management influences the central executive control system that regulates processing across a wide range of task demands. Furthermore, the results show that bilingual cognitive advantages are found in socioeconomically disadvantaged bilingual populations and suggest that benefits to executive control are moderated by bilingual proficiency. PMID:25160938

  12. Effectiveness of a Smoking Cessation Intervention in Dutch Pharmacies and General Practices

    ERIC Educational Resources Information Center

    Hoving, Ciska; Mudde, Aart N.; Dijk, Froukje; de Vries, Hein

    2010-01-01

    Purpose: The purpose of this paper is to test the effectiveness of a computer-tailored smoking cessation intervention, distributed through 75 Dutch general practices (GP) and 65 pharmacies (PH) in a randomised control trial. Design/methodology/approach: Respondents receive a tailored letter or a thank you letter (control condition). Main outcome…

  13. Learning the Spelling of Strange Words in Dutch Benefits from Regularized Reading

    ERIC Educational Resources Information Center

    Bosman, Anna M. T.; van Hell, Janet G.; Verhoeven, Ludo

    2006-01-01

    In two experiments, the authors tested the effect of two types of reading on the spelling memory of strange or sound-spelling inconsistent words in Dutch students with and without learning disabilities: standard reading and regularized reading. Standard reading refers to reading the word the way it has to be read. Regularized reading refers to…

  14. Comparison of Dutch Ethnic Minority and Majority Engineering Students: Social and Academic Integration

    ERIC Educational Resources Information Center

    Severiens, Sabine; ten Dam, Geert; Blom, Sarah

    2006-01-01

    Study careers of minority students in Dutch higher education are still less successful compared with the careers of majority students. Minority students still seem to experience more difficulties than majority students. Vincent Tinto's twin concepts of academic and social integration are used here to explore the experiences of minority and…

  15. Substitution of Dental Fricatives in English by Dutch L2 Speakers

    ERIC Educational Resources Information Center

    Wester, Femke; Gilbers, Dicky; Lowie, Wander

    2007-01-01

    This paper investigates the nature of the substitutions used for the dental fricatives (/theta/ and /eth/) by Dutch learners of English as a second language. By means of an OT analysis, the underlying reasons for the difficulties encountered with these sounds are brought to light. The present data reveal that phonetics (or acoustics) rather than…

  16. Moving Forward? Addressing the Needs of Young At-Risk Students in the Dutch Education System

    ERIC Educational Resources Information Center

    van der Aalsvoort, Geerdina M.

    2007-01-01

    Inclusive education in the Dutch education system has achieved new meaning in the last decade or so. Until 1998, the Netherlands recognized 19 types of special education. Then, two Educational Acts were passed, in 1998 and 2003, that decreased the types of special education by including measures to enhance inclusion of students with special…

  17. Aspects of Language Choice in the Frisian-Dutch Bilingual Context: Neutrality and Asymmetry.

    ERIC Educational Resources Information Center

    Gorter, Durk

    1987-01-01

    Preliminary results from a large research project on the use of Frisian and Dutch in the official domain in Friesland focuses on language use in contacts between civil servants and customers in service encounters. Language patterns observed include convergence, neutrality, switching, and asymmetry. (CB)

  18. An Exploratory Case Study of Dutch Children's Attitudes toward Consumption: Implications for Environmental Education

    ERIC Educational Resources Information Center

    Kopnina, Helen

    2013-01-01

    This critical essay based on empirical study draws upon research on the differences in attitudes toward consumption among Dutch upper-elementary school children with different socioeconomic backgrounds. This article examines two strands of theory: critical literature on the conceptualization and practice of sustainable consumption, and the theory…

  19. Acceptability of the Components of a Loneliness Intervention among Elderly Dutch People: A Qualitative Study

    ERIC Educational Resources Information Center

    Honigh-de Vlaming, R.; Haveman-Nies, A.; Ziylan, C.; Renes, R. J.

    2013-01-01

    Background: Healthy Ageing is a complex intervention aimed at reducing the prevalence of loneliness among elderly Dutch people. Purpose: This study aimed to assess how mass media communication materials, information meetings, and psychosocial courses were received by elderly people at high risk of loneliness. Methods: Face-to-face interviews with…

  20. Age and Input in the Acquisition of Grammatical Gender in Dutch

    ERIC Educational Resources Information Center

    Unsworth, Sharon

    2008-01-01

    This article investigates the effect of age of first exposure and the quantity and quality of input to which non-native acquirers (L2ers) are exposed in their acquisition of grammatical gender in Dutch. Data from 103 English-speaking children, preteens and adults were analyzed for gender agreement on definite determiners. It was observed that…

  1. Phonological Awareness and Naming Speed in the Prediction of Dutch Children's Word Recognition

    ERIC Educational Resources Information Center

    Verhagen, W.; Aarnoutse, C.; van Leeuwe, J.

    2008-01-01

    Influences of phonological awareness and naming speed on the speed and accuracy of Dutch children's word recognition were investigated in a longitudinal study. The speed and accuracy of word recognition at the ends of Grades 1 and 2 were predicted by naming speed from both the beginning and end of Grade 1, after control for autoregressive…

  2. Communicating Astronomy with a Mass Audience — BBC's Stargazing Live goes Dutch

    NASA Astrophysics Data System (ADS)

    Baan, M.

    2015-06-01

    Following on from the hugely successful airing of Heel Nederland Kijkt Sterren — a Dutch stargazing event modelled on the BBC's programme Stargazing Live — this article explores some of the issues involved in communicating astronomy directly to a mass audience. This includes the production process, co-sponsorship, content, the reach and lessons learned.

  3. Prefixes as Access Units in Visual Word Recognition: A Comparison of Italian and Dutch Data.

    ERIC Educational Resources Information Center

    Assink, Egbert M. H.; Vooijs, Caroline; Knuijt, Paul P. N. A.

    2000-01-01

    Compares morphological processing of skilled and less skilled Dutch readers. Focuses on the role of prefixes as access units in visual word recognition. Finds evidence for differential use of prefix information in undergraduate students and elementary school children. Concludes that the information accessed by prefixes is semantically combined…

  4. Creating Critical-Democratic Citizenship Education: Empowering Humanity and Democracy in Dutch Education

    ERIC Educational Resources Information Center

    Veugelers, Wiel

    2007-01-01

    Dutch society and educational policy see citizenship education as being an important task of education. The first section of this paper discusses the concept of citizenship and citizenship education, and analyses educational developments in the Netherlands. Following on from this introduction the second part of the paper puts forward a critical…

  5. Scalar Meanings, Inferential Complexity, and Communicative Function: The Semantics and Pragmatics of Deixis in Modern Dutch.

    ERIC Educational Resources Information Center

    Kirsner, Robert S.

    The Dutch deictics are typically given a locative analysis: the adverbial pronoun "hier" ("here") and the demonstrative "deze" ("this") are said to point near the speaker, "daar" ("there") and "die" ("that") to point far, with "er" (weak "there") and the article "de" ("the") left unspecified (Bech 1952:7). The present paper rejects this view,…

  6. Which Way with Informatics in High Schools in the Netherlands? The Dutch Dilemma

    ERIC Educational Resources Information Center

    van Diepen, Nico; Perrenet, Jacob; Zwaneveld, Bert

    2011-01-01

    Informatics is currently being taught in high schools all over the world. In the Dutch curriculum, computer literacy is taught in the lower grades as a compulsory subject, Informatics is taught as an elective in the higher grades of some schools. As a follow-up to the outline of Grgurina and Tolboom (2008), the discussion about the future of…

  7. Orthographic Learning and the Role of Text-to-Speech Software in Dutch Disabled Readers

    ERIC Educational Resources Information Center

    Staels, Eva; Van den Broeck, Wim

    2015-01-01

    In this study, we examined whether orthographic learning can be demonstrated in disabled readers learning to read in a transparent orthography (Dutch). In addition, we tested the effect of the use of text-to-speech software, a new form of direct instruction, on orthographic learning. Both research goals were investigated by replicating…

  8. Acquisition of /s/-Clusters in Dutch-Speaking Children with Phonological Disorders

    ERIC Educational Resources Information Center

    Gerrits, Ellen

    2010-01-01

    This study investigated the acquisition of word initial s clusters of 3-5 year old Dutch children with phonological disorders. Within these clusters, sl was produced correctly most often, whereas sn and sx were the more difficult clusters. In cluster reductions, s+obstruent and sl clusters reduction patterns followed the Sonority Sequencing…

  9. Perceptions of "Nursing" and "Nursing Care" in the United States by Dutch Nursing Students.

    ERIC Educational Resources Information Center

    Haloburdo, Esther P.; Thompson, Mary Ann

    2001-01-01

    In the opinions of 11 Dutch nursing students on a study tour of the United States, the U.S. emphasizes technical aspects of nursing and medical over nursing care, lacks team nursing and collegiality, and has a litigious environment. These negative images have implications for the use of U.S. nursing as a benchmark for global education and…

  10. Coping with Academic Failure, a Study of Dutch Children with Dyslexia

    ERIC Educational Resources Information Center

    Singer, Elly

    2008-01-01

    This paper reports the results of a study of strategies that Dutch children with dyslexia employ to cope with recurrent academic failure. All of the students in the study had developed strategies for protecting their self-esteem. Using Harter's theory of coping with discrepancies between performance and standards, we distinguish four strategies:…

  11. Predicting Trajectories of Offending over the Life Course: Findings from a Dutch Conviction Cohort

    ERIC Educational Resources Information Center

    Bersani, Bianca E.; Nieuwbeerta, Paul; Laub, John H.

    2009-01-01

    Distinguishing trajectories of criminal offending over the life course, especially the prediction of high-rate offenders, has received considerable attention over the past two decades. Motivated by a recent study by Sampson and Laub (2003), this study uses longitudinal data on conviction histories from the Dutch Criminal Career and Life-Course…

  12. Benefits and Costs of Privatized Public Services: Lessons from the Dutch Educational System.

    ERIC Educational Resources Information Center

    James, Estelle

    1984-01-01

    Examines the possibility of "privitizing" education (a government policy, such as a voucher or tax credit system, which combines public financing with private production of the service). Describes the Dutch system of publicly funded private education. Suggests that private organizations and local governments find themselves competing to provide…

  13. Determining Subjectivity in Text: The Case of Backward Causal Connectives in Dutch

    ERIC Educational Resources Information Center

    Pit, Mirna

    2006-01-01

    This article addresses the question of how to systematically determine the degree of subjectivity expressed in a text, more specifically, the degree of subjectivity expressed in causal coherence relations. The main hypothesis is that the distribution of Dutch backward causal connectives (want, omdat, aangezien, and doordat) can be explained by the…

  14. Perceived Teacher-Student Interpersonal Relationships in Dutch Multi-Ethnic Classes

    ERIC Educational Resources Information Center

    den Brok, Perry; Wubbels, Theo; Veldman, Ietje; van Tartwijk, Jan

    2009-01-01

    Research on students' perceptions of the teacher-student interpersonal relationship in multi-ethnic classes is scarce in Europe. This study compares students' perceptions in multi-ethnic classes in The Netherlands with those in mainstream Dutch classes and investigates differences in perceptions between students with various ethnic backgrounds.…

  15. Motives Underlying Bachelors-Masters Transitions: The Case of Dutch Degree Stackers

    ERIC Educational Resources Information Center

    de Boer, Harry; Kolster, Renze; Vossensteyn, Hans

    2010-01-01

    In the light of the Bologna process, traditional degree programmes of research-led universities in the Netherlands have been transformed into 3 year bachelors programmes and 1 or 2 year masters programmes. The Dutch universities of applied sciences (UAS) mainly offer 4 year bachelors programmes. In principle, this UAS bachelors degree qualifies…

  16. Individualism and the "Western Mind" Reconsidered: American and Dutch Parents' Ethnotheories of the Child.

    ERIC Educational Resources Information Center

    Harkness, Sara; Super, Charles M.; van Tijen, Nathalie

    2000-01-01

    Compares descriptions and interpretations of their children's personality and behavior among Dutch and American parents' of infants to 8-year-olds. Analysis of relevant descriptors in parents' discourse and how they talked about core constructs of dependence, and independence reveals a systematic difference defying simple dichotomies of…

  17. Dutch Children at Family Risk of Dyslexia: Precursors, Reading Development, and Parental Effects

    ERIC Educational Resources Information Center

    van Bergen, Elsje; de Jong, Peter F.; Regtvoort, Anne; Oort, Frans; van Otterloo, Sandra; van der Leij, Aryan

    2011-01-01

    The study concerns reading development and its precursors in a transparent orthography. Dutch children differing in family risk for dyslexia were followed from kindergarten through fifth grade. In fifth grade, at-risk dyslexic (n = 22), at-risk non-dyslexic (n = 45), and control children (n = 12) were distinguished. In kindergarten, the at-risk…

  18. Predictors of Response to Intervention of Word Reading Fluency in Dutch

    ERIC Educational Resources Information Center

    Scheltinga, Femke; van der Leij, Aryan; Struiksma, Chris

    2010-01-01

    The objective of this study was to investigate the contribution of rapid digit naming, phonological memory, letter sound naming, and orthographic knowledge to the prediction of responsiveness to a school-based, individual intervention of word reading fluency problems of 122 Dutch second and third graders whose reading scores were below the 10th…

  19. The Affect and Arousal Scales: Psychometric Properties of the Dutch Version and Multigroup Confirmatory Factor Analyses

    ERIC Educational Resources Information Center

    De Bolle, Marleen; De Fruyt, Filip; Decuyper, Mieke

    2010-01-01

    Psychometric properties of the Dutch version of the Affect and Arousal Scales (AFARS) were inspected in a combined clinical and population sample (N = 1,215). The validity of the tripartite structure and the relations between Negative Affect, Positive Affect, and Physiological Hyperarousal (PH) were investigated for boys and girls, younger (8-11…

  20. The Dutch Memory Compensation Questionnaire: Psychometric Properties and Regression-Based Norms

    ERIC Educational Resources Information Center

    Van der Elst, Wim; Hoogenhout, Esther M.; Dixon, Roger A.; De Groot, Renate H. M.; Jolles, Jelle

    2011-01-01

    The Memory Compensation Questionnaire (MCQ) is a psychometrically sound instrument that assesses the variety and extent to which an individual compensates for actual or perceived memory losses. Until now, only an English version of the MCQ has been psychometrically evaluated. The aim of the present study was to establish a Dutch version of the MCQ…

  1. Neoliberal Individualism in Dutch Universities: Teaching and Learning Anthropology in an Insecure Environment

    ERIC Educational Resources Information Center

    Bal, Ellen; Grassiani, Erella; Kirk, Kate

    2014-01-01

    This article is based on our own experiences and that of several of our colleagues teaching social and cultural anthropology in different Dutch institutions for higher learning. We focus in particular on teaching and learning in two small liberal arts and science (LAS) colleges, where anthropology makes up part of the social science curriculum…

  2. Construct Validation of the Dutch Version of the Impact of Event Scale

    ERIC Educational Resources Information Center

    van der Ploeg, Eleonore; Mooren, Trudy T. M.; Kleber, Rolf J.; van der Velden, Peter G.; Brom, Danny

    2004-01-01

    The Impact of Event Scale (ES; M. J. Horowitz, N. Wilner, & W. Alvarez, 1979) is a worldwide-used self-report measure to assess the frequency of intrusive and avoidant phenomena after a variety of traumatic experiences. The purpose of this article is to assess the psychometric value of the Dutch version of the IES (D. Brom & R. J. Kleber, 1985) in…

  3. Morpheme Frequency Effects in Dutch Complex Word Reading: A Developmental Perspective

    ERIC Educational Resources Information Center

    Verhoeven, Ludo; Schreuder, Rob

    2011-01-01

    This study examined to what extent advanced and beginning readers, including dyslexic readers of Dutch, make use of morphological access units in the reading of polymorphemic words. Therefore, experiments were carried out in which the role of singular root form frequency in reading plural word forms was investigated in a lexical decision task with…

  4. Parent-Reported Feeding and Feeding Problems in a Sample of Dutch Toddlers

    ERIC Educational Resources Information Center

    de Moor, Jan; Didden, Robert; Korzilius, Hubert

    2007-01-01

    Little is known about the feeding behaviors and problems with feeding in toddlers. In the present questionnaire study, data were collected on the feeding behaviors and feeding problems in a relatively large (n = 422) sample of Dutch healthy toddlers (i.e. 18-36 months old) who lived at home with their parents. Results show that three meals a day…

  5. Consonantal and Syllabic Repairs of Arabic and Dutch Loanwords in Indonesian: A Phonological Account

    ERIC Educational Resources Information Center

    Batais, Saleh Saeed

    2013-01-01

    The dissertation study aims to contribute mainly to the field of loanword phonology in general and particularly to Indonesian and its phonology that are rarely studied to date. The study investigates what consonantal and syllabic repair strategies are employed by Indonesian in adapting Arabic and Dutch loanwords, whether these adaptation…

  6. Conflicts about Water: A Case Study of Contest and Power in Dutch Rural Policy

    ERIC Educational Resources Information Center

    Boonstra, Wijnand; Frouws, Jaap

    2005-01-01

    The Dutch countryside forms the scene for pressing problems of management and allocation of land and water. These problems underscore the need for comprehensive rural policies. For that purpose, area-based rural policy has been initiated. This new policy is part of a larger policy shift, labelled in literature as "new rural governance". Area-based…

  7. Adaptive Strategies, Gender Ideology, and Work-Family Balance among Dutch Dual Earners

    ERIC Educational Resources Information Center

    Wierda-Boer, Hilde H.; Gerris, Jan R. M.; Vermulst, Ad A.

    2008-01-01

    Using questionnaire data on 149 Dutch dual-earner couples with young children participating in the European Famwork study, we examine how adaptive strategies and gender ideology relate to parents' perceived success in balancing work and family. Path analysis indicates that some adaptive strategies may harm individuals' work-family balance,…

  8. Academic Drift in Dutch Non-University Higher Education Evaluated: A Staff Perspective

    ERIC Educational Resources Information Center

    Griffioen, Didi M. E.; de Jong, Uulkje

    2013-01-01

    In the context of a European knowledge economy, the Dutch non-university institutions systematically develop research activities at a higher frequency than before. With this development, they have been accused of academic drift, of striving to receive a status comparable to traditional universities. This study considers the perceptions of both…

  9. Alignment of "Phrase Accent" Lows in Dutch Falling Rising Questions: Theoretical and Methodological Implications

    ERIC Educational Resources Information Center

    Lickley, Robin J.; Schepman, Astrid; Ladd, D. Robert

    2005-01-01

    In the first part of this study, we measured the alignment (relative to segmental landmarks) of the low F0 turning points between the accentual fall and the final boundary rise in short Dutch falling-rising questions of the form "Do you live in [place name]?" produced as read speech in a laboratory setting. We found that the alignment of these…

  10. Utility of the PASS Theory and Cognitive Assessment System for Dutch Children with and without ADHD

    ERIC Educational Resources Information Center

    Van Luit, Johannes E. H.; Kroesbergen, Evelyn H.; Naglieri, Jack A.

    2005-01-01

    This study examined the utility of the Planning, Attention, Simultaneous, Successive (PASS) theory of intelligence as measured by the "Cognitive Assessment System" (CAS) for evaluation of children with attention-deficit/hyperactivity disorder (ADHD). The CAS scores of 51 Dutch children without ADHD were compared to the scores of a group of 20…

  11. Perception and Production of the Final /s-ts/ Contrast in Dutch by Misarticulating Children.

    ERIC Educational Resources Information Center

    Raaymakkers, Emile M. J. A.; Crul, Thom A. M.

    1988-01-01

    The relationship between speech perception and speech production was investigated, by comparing five six and seven-year-old Dutch children who misarticulated the final consonant cluster /-ts/ with three control groups. Results indicate that the poorer the articulation proficiency of a group, the more variability there was in both production and…

  12. Comparing Deaf and Hearing Dutch Infants: Changes in the Vowel Space in the First 2 Years

    ERIC Educational Resources Information Center

    van der Stelt, Jeannette M.; Wempe, Ton G.; Pols, Louis C. W.

    2008-01-01

    The influence of the mother tongue on vowel productions in infancy is different for deaf and hearing babies. Audio material of five hearing and five deaf infants acquiring Dutch was collected monthly from month 5-18, and at 24 months. Fifty unlabelled utterances were digitized for each recording. This study focused on developmental paths in vowel…

  13. A Cross Cultural Examination of Creative Problem Solving Style: The Dutch Translation of VIEW

    ERIC Educational Resources Information Center

    Isaksen, Scott G.; De Schryver, Luc; Onkelinx, Jonas

    2010-01-01

    Creativity and Creative Problem Solving are globally important. This study examined the cross-cultural applicability of creative problem solving styles by translating VIEW: An Assessment of Problem Solving Style from its native English into Dutch and examining its psychometric properties and preliminary validation evidence. In general, support was…

  14. Changes in Student Populations and Average Test Scores of Dutch Primary Schools

    ERIC Educational Resources Information Center

    Luyten, Hans; de Wolf, Inge

    2011-01-01

    This article focuses on the relation between student population characteristics and average test scores per school in the final grade of primary education from a dynamic perspective. Aggregated data of over 5,000 Dutch primary schools covering a 6-year period were used to study the relation between changes in school populations and shifts in mean…

  15. Acoustic Analysis of the Voiced-Voiceless Distinction in Dutch Tracheoesophageal Speech

    ERIC Educational Resources Information Center

    Jongmans, Petra; Wempe, Ton G.; van Tinteren, Harm; Hilgers, Frans J. M.; Pols, Louis C. W.; van As-Brooks, Corina J.

    2010-01-01

    Purpose: Confusions between voiced and voiceless plosives and voiced and voiceless fricatives are common in Dutch tracheoesophageal (TE) speech. This study investigates (a) which acoustic measures are found to convey a correct voicing contrast in TE speech and (b) whether different measures are found in TE speech than in normal laryngeal (NL)…

  16. The Predictive Power of Phonemic Awareness and Naming Speed for Early Dutch Word Recognition

    ERIC Educational Resources Information Center

    Verhagen, Wim G. M.; Aarnoutse, Cor A. J.; van Leeuwe, Jan F. J.

    2009-01-01

    Effects of phonemic awareness and naming speed on the speed and accuracy of Dutch children's word recognition were investigated in a longitudinal study. Both the speed and accuracy of word recognition at the end of Grade 2 were predicted by naming speed from both kindergarten and Grade 1, after control for autoregressive relations, kindergarten…

  17. Hunting Reynard: How "Reynard the Fox" Tricked His Way into English and Dutch Children's Literature

    ERIC Educational Resources Information Center

    Parlevliet, Sanne

    2008-01-01

    This article examines adaptations in their capacity of preserving literary heritage. It describes how the Middle Dutch beast epic "Reynard the Fox" lost its position in literature for adults and became part of a literary heritage that was no longer read but only studied for its historical value. Versions for children kept the story alive. A…

  18. Evaluation of the ADOS Revised Algorithm: The Applicability in 558 Dutch Children and Adolescents

    ERIC Educational Resources Information Center

    de Bildt, Annelies; Sytema, Sjoerd; van Lang, Natasja D. J.; Minderaa, Ruud B.; van Engeland, Herman; de Jonge, Maretha V.

    2009-01-01

    The revised ADOS algorithms, proposed by Gotham et al. (J Autism Dev Disord 37:613-627, 2007), were investigated in an independent sample of 558 Dutch children (modules 1, 2 and 3). The revised algorithms lead to better balanced sensitivity and specificity for modules 2 and 3, without losing efficiency of the classification. Including the…

  19. Physical properties of immiscible polymers

    NASA Technical Reports Server (NTRS)

    Harris, J. Milton

    1987-01-01

    The demixing of immiscible polymers in low gravity is discussed. Applications of knowledge gained in this research will provide a better understanding of the role of phase segregation in determining the properties of polymer blends made from immiscible polymers. Knowledge will also be gained regarding the purification of biological materials by partitioning between the two liquid phases formed by solution of the polymers polyethylene glycol and dextran in water. Testing of new apparatus for space flight, extension of affinity phase partitioning, refinement of polymer chemistry, and demixing of isopycnic polymer phases in a one gravity environment are discussed.

  20. Piezoresistance in Polymer Nanocomposites

    NASA Astrophysics Data System (ADS)

    Rizvi, Reza

    Piezoresistivity in conductive polymer nanocomposites occurs because of the disturbance of particle networks in the polymer matrix. The piezoresistance effect becomes more prominent if the matrix material is compliant making these materials attractive for applications that require flexible force and displacement sensors such as e-textiles and biomechanical measurement devices. However, the exact mechanisms of piezoresistivity including the relationship between the matrix polymer, conductive particle, internal structure and the composite's piezoresistance need to be better understood before it can be applied for such applications. The objective of this thesis is to report on the development of conductive polymer nanocomposites for use as flexible sensors and electrodes. Electrically conductive and piezoresistive nanocomposites were fabricated by a scalable melt compounding process. Particular attention was given to elucidating the role of matrix and filler materials, plastic deformation and porosity on the electrical conduction and piezoresistance. These effects were parametrically investigated through characterizing the morphology, electrical properties, rheological properties, and piezoresistivity of the polymer nanocomposites. The electrical and rheological behavior of the nanocomposites was modeled by the percolation-power law. Furthermore, a model was developed to describe the piezoresistance behavior during plastic deformation in relation to the stress and filler concentration.

  1. Processing of semicrystalline polymers

    NASA Technical Reports Server (NTRS)

    Cebe, Peggy; Brillhart, Mark V.

    1993-01-01

    Our research group has been interested in the processing-structure-property relationships in semicrystalline polymers and blends for many years. In situ real time x ray scattering at elevated temperatures is being used to monitor the development of structure. An ongoing collaboration with Dr. Malcolm Capel at the Brookhaven National Synchrotron Light Source allows the performance of real time wide and small angle x ray scattering to study the phase transformations in semicrystalline polymers. The first part of my presentation will be about our recent use of x ray scattering to study blends of poly(ethylene terephthalate) with polyarylates. The purpose of the next portion of the presentation is to show how we may study effects of self-deformation of polymers during processing in the gravity environment, using real time x ray scattering. In this way, how processing stresses alter the microstructure of semicrystalline polymers was learned, and ultimately microgravity processing strategies that will result in more uniform morphology in these polymers is hoped to be developed.

  2. Calibration and Validation of the Dutch-Flemish PROMIS Pain Interference Item Bank in Patients with Chronic Pain.

    PubMed

    Crins, Martine H P; Roorda, Leo D; Smits, Niels; de Vet, Henrica C W; Westhovens, Rene; Cella, David; Cook, Karon F; Revicki, Dennis; van Leeuwen, Jaap; Boers, Maarten; Dekker, Joost; Terwee, Caroline B

    2015-01-01

    The Dutch-Flemish PROMIS Group translated the adult PROMIS Pain Interference item bank into Dutch-Flemish. The aims of the current study were to calibrate the parameters of these items using an item response theory (IRT) model, to evaluate the cross-cultural validity of the Dutch-Flemish translations compared to the original English items, and to evaluate their reliability and construct validity. The 40 items in the bank were completed by 1085 Dutch chronic pain patients. Before calibrating the items, IRT model assumptions were evaluated using confirmatory factor analysis (CFA). Items were calibrated using the graded response model (GRM), an IRT model appropriate for items with more than two response options. To evaluate cross-cultural validity, differential item functioning (DIF) for language (Dutch vs. English) was examined. Reliability was evaluated based on standard errors and Cronbach's alpha. To evaluate construct validity correlations with scores on legacy instruments (e.g., the Disabilities of the Arm, Shoulder and Hand Questionnaire) were calculated. Unidimensionality of the Dutch-Flemish PROMIS Pain Interference item bank was supported by CFA tests of model fit (CFI = 0.986, TLI = 0.986). Furthermore, the data fit the GRM and showed good coverage across the pain interference continuum (threshold-parameters range: -3.04 to 3.44). The Dutch-Flemish PROMIS Pain Interference item bank has good cross-cultural validity (only two out of 40 items showing DIF), good reliability (Cronbach's alpha = 0.98), and good construct validity (Pearson correlations between 0.62 and 0.75). A computer adaptive test (CAT) and Dutch-Flemish PROMIS short forms of the Dutch-Flemish PROMIS Pain Interference item bank can now be developed. PMID:26214178

  3. Measuring safety culture in Dutch primary care: psychometric characteristics of the SCOPE-PC questionnaire

    PubMed Central

    2013-01-01

    Background Patient safety has been a priority in primary healthcare in the last years. The prevailing culture is seen as an important condition for patient safety in practice and several tools to measure patient safety culture have therefore been developed. Although Dutch primary care consists of different professions, such as general practice, dental care, dietetics, physiotherapy and midwifery, a safety culture questionnaire was only available for general practices. The purpose of this study was to modify and validate this existing questionnaire to a generic questionnaire for all professions in Dutch primary care. Methods A validated Dutch questionnaire for general practices was modified to make it usable for all Dutch primary care professions. Subsequently, this questionnaire was administered to a random sample of 2400 practices from eleven primary care professions. The instrument’s factor structure, reliability and validity were examined using confirmatory and explorative factor analyses. Results 921 questionnaires were returned. Of these, 615 were eligible for factor analysis. The resulting SCOPE-PC questionnaire consisted of seven dimensions: ‘open communication and learning from errors’, ‘handover and teamwork’, ‘adequate procedures and working conditions’, ‘patient safety management’, ‘support and fellowship’, ‘intention to report events’ and ‘organisational learning’ with a total of 41 items. All dimensions had good reliability with Cronbach’s alphas ranging from 0.70 – 0.90, and the questionnaire had a good construct validity. Conclusions The SCOPE-PC questionnaire has sound psychometric characteristics for use by the different professions in Dutch primary care to gain insight in their safety culture. PMID:24044750

  4. Fatal grand mal seizure in a Dutch trekker.

    PubMed

    Basnyat, B

    1998-12-01

    A 35-year-old healthy Dutch woman went on a trek (Lang Tang) in Nepal up to an approximate altitude of about 3800 meters. She had no prior history of any medical problems except attacks of generalized epilepsy when she was 19 years old, which had been controlled with antiepileptic medications. She had had no attacks after the age of 20. A CT scan done around that time had apparently been normal. On this trek she had developed diarrhea which had been cured with norfloxacin 400 mg two times per day for 3 days. Two days later, while descending, she developed a grand mal seizure at an altitude of 3300 meters, after which she developed a classic postictal phase but gradually recovered. She developed grand mal seizures again the next day, but when she went to a travel clinic in Kathmandu, she had been seizure free for 72 hours. She also revealed that she had not suffered from acute mountain sickness on the trek. She also had a prior history of gastroenteritis at high altitude which improved significantly with norfloxacin, a quinolone antibiotic. This was corroborated by her party. Upon examination she was fully conscious and oriented to person, place and time. Her pulse was 70 beats per minute and her BP was 110/80 mm of Hg. Her fundi and cranial nerves exam were completely normal. Her abstract thinking, gait, power, tone, reflexes and other facets of her neurologic exam revealed absolutely no abnormalities. Her cardiovascular exam revealed a normal rhythm with no murmurs or bruits. The rest of her exam was also normal. She revealed that she played tennis on a regular basis and was an outdoor person. She had not trekked before in the Himalayas and it was uncertain if she had been to high altitude before. She was on no medications at the time. There was no history of drug abuse. She did not smoke and consumed few alcoholic beverages. She had not consumed any alcohol on the trek. She was advised to get a CT scan (she declined as she was going home to Holland in 2 days) and

  5. Antithrombogenic Polymer Coating.

    DOEpatents

    Huang, Zhi Heng; McDonald, William F.; Wright, Stacy C.; Taylor, Andrew C.

    2003-01-21

    An article having a non-thrombogenic surface and a process for making the article are disclosed. The article is formed by (i) coating a polymeric substrate with a crosslinked chemical combination of a polymer having at least two amino substituted side chains, a crosslinking agent containing at least two crosslinking functional groups which react with amino groups on the polymer, and a linking agent containing a first functional group which reacts with a third functional group of the crosslinking agent, and (ii) contacting the coating on the substrate with an antithrombogenic agent which covalently bonds to a second functional group of the linking agent. In one example embodiment, the polymer is a polyamide having amino substituted alkyl chains on one side of the polyamide backbone, the crosslinking agent is a phosphine having the general formula (A).sub.3 P wherein A is hydroxyalkyl, the linking agent is a polyhydrazide and the antithrombogenic agent is heparin.

  6. Liquid crystalline polymers

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The remarkable mechanical properties and thermal stability of fibers fabricated from liquid crystalline polymers (LCPs) have led to the use of these materials in structural applications where weight savings are critical. Advances in processing of LCPs could permit the incorporation of these polymers into other than uniaxial designs and extend their utility into new areas such as nonlinear optical devices. However, the unique feature of LCPs (intrinsic orientation order) is itself problematic, and current understanding of processing with control of orientation falls short of allowing manipulation of macroscopic orientation (except for the case of uniaxial fibers). The current and desirable characteristics of LCPs are reviewed and specific problems are identified along with issues that must be addressed so that advances in the use of these unique polymers can be expedited.

  7. Flame spraying of polymers

    SciTech Connect

    Varacalle, D.J. Jr.; Zeek, D.P.; Couch, K.W.; Benson, D.M.; Kirk, S.M.

    1997-08-01

    Statistical design-of-experiment studies of the thermal spraying of polymer powders are presented. Studies of the subsonic combustion (i.e., Flame) process were conducted in order to determine the quality and economics of polyester and urethane coatings. Thermally sprayed polymer coatings are of interest to several industries for anticorrosion applications, including the chemical, automotive, and aircraft industries. In this study, the coating design has been optimized for a site-specific application using Taguchi-type fractional-factorial experiments. Optimized coating designs are presented for the two powder systems. A substantial range of thermal processing conditions and their effect on the resultant polymer coatings is presented. The coatings were characterized by optical metallography, hardness testing, tensile testing, and compositional analysis. Characterization of the coatings yielded the thickness, bond strength, Knoop microhardness, roughness, deposition efficiency, and porosity. Confirmation testing was accomplished to verify the coating designs.

  8. Inorganic polymer engineering materials

    SciTech Connect

    Stone, M.L.

    1993-06-01

    Phosphazene-based, inorganic-polymer composites have been produced and evaluated as potential engineering materials. The thermal, chemical, and mechanical properties of several different composites made from one polymer formulation have been measured. Measured properties are very good, and the composites show excellent promise for structural applications in harsh environments. Chopped fiberglass, mineral, cellulose, and woodflour filled composites were tested. Chopped fiberglass filled composites showed the best overall properties. The phosphazene composites are very hard and rigid. They have low dielectric constants and typical linear thermal expansion coefficients for polymers. In most cases, the phosphazene materials performed as well or better than analogous, commercially available, filled phenolic composites. After 3 to 5 weeks of exposure, both the phosphazene and phenolics were degraded to aqueous bases and acids. The glass filled phosphazene samples were least affected.

  9. Polymer infiltration studies

    NASA Technical Reports Server (NTRS)

    Marchello, Joseph M.

    1992-01-01

    Progress was made in several areas on the preparation of carbon fiber composites using advanced polymer resins. Polymer infiltration studies dealt with ways of preparing composite materials from advanced polymer resins and carbon fibers. This effort is comprised of an integrated approach to the process of composite part fabrication. The goal is to produce advanced composite materials for automated part fabrication using textile and robotics technology in the manufacture of subsonic and supersonic aircraft. The object is achieved through investigations at the NASA Langley Research Center and by stimulating technology transfer between contract researchers and the aircraft industry. Covered here are literature reviews, a status report on individual projects, current and planned research, publications, and scheduled technical presentations.

  10. Terahertz Spectroscopy of Polymers

    NASA Astrophysics Data System (ADS)

    Jansen, Christian; Wietzke, Steffen; Koch, Martin

    Polymers and terahertz (THz) waves form a fruitful symbiosis: on the one hand, non-polar plastics serve as base materials for THz optics as they exhibit low absorption and excellent machinability. On the other hand, THz time-domain spectroscopy (TDS) grants access to unique information about the molecular structure and morphology of polymers, offering an immense portfolio of interesting scientific opportunities. Furthermore, contact-free, non-destructive testing with non-ionizing THz radiation could evolve as a valuable addition to or substitution of ultrasonic and X-ray characterization, especially in quality inspection and process control applications. This chapter aims to give an overview of recent activities in this field, covering both the spectroscopic analysis of polymers with THz waves as well as the non-destructive testing of plastic components with THz systems.

  11. Atomic Oxygen Textured Polymers

    NASA Technical Reports Server (NTRS)

    Banks, Bruce A.; Rutledge, Sharon K.; Hunt, Jason D.; Drobotij, Erin; Cales, Michael R.; Cantrell, Gidget

    1995-01-01

    Atomic oxygen can be used to microscopically alter the surface morphology of polymeric materials in space or in ground laboratory facilities. For polymeric materials whose sole oxidation products are volatile species, directed atomic oxygen reactions produce surfaces of microscopic cones. However, isotropic atomic oxygen exposure results in polymer surfaces covered with lower aspect ratio sharp-edged craters. Isotropic atomic oxygen plasma exposure of polymers typically causes a significant decrease in water contact angle as well as altered coefficient of static friction. Such surface alterations may be of benefit for industrial and biomedical applications. The results of atomic oxygen plasma exposure of thirty-three (33) different polymers are presented, including typical morphology changes, effects on water contact angle, and coefficient of static friction.

  12. Thermally tunable polymer microlenses

    NASA Astrophysics Data System (ADS)

    Huang, Xian; Cheng, Chao-Min; Wang, Li; Wang, Bin; Su, Chih-Chuan; Ho, Mon-Shu; LeDuc, Philip R.; Lin, Qiao

    2008-06-01

    Polymer microlenses capable of using heat to control its focal length are presented. The microlenses are created by exposing droplets of the polymer SU-8 to UV light. By altering the temperature of the microlenses via on-chip heating, their curvature and focal length are actively controlled without mechanical movements. By directly and indirectly measuring temperature-dependent changes of the focal length, we test the ability of the microlenses as a tunable imaging component. The microlenses have potential use in applications such as laser systems, functional biomimetics, and endoscopy.

  13. Trifluoromethyl-substituted polymers

    NASA Technical Reports Server (NTRS)

    Cassidy, Patrick E.

    1990-01-01

    The synthesis of polymers is discussed. It includes: (1) the synthesis of fluorine-containing crosslinked poly(ether ketones); (2) the synthesis and characterization of poly(imide amides) and their N-methylated analogues; (3) the synthesis of fluorine-containing aromatic polyethers; (4) the synthesis of novel fluorine-containing aromatic polysiloxanes; and (5) the conversion of 6F-containing polythioethers to polysulfones. It is hoped that these polymers will find use as low dielectric materials in electronic applications, function as thermal control coatings, or be suitable elastomeric sealants for extreme service conditions.

  14. Randomly Hyperbranched Polymers

    NASA Astrophysics Data System (ADS)

    Konkolewicz, Dominik; Gilbert, Robert G.; Gray-Weale, Angus

    2007-06-01

    We describe a model for the structures of randomly hyperbranched polymers in solution, and find a logarithmic growth of radius with polymer mass. We include segmental overcrowding, which puts an upper limit on the density. The model is tested against simulations, against data on amylopectin, a major component of starch, on glycogen, and on polyglycerols. For samples of synthetic polyglycerol and glycogen, our model holds well for all the available data. The model reveals higher-level scaling structure in glycogen, related to the β particles seen in electron microscopy.

  15. Nanoparticles from renewable polymers

    PubMed Central

    Wurm, Frederik R.; Weiss, Clemens K.

    2014-01-01

    The use of polymers from natural resources can bring many benefits for novel polymeric nanoparticle systems. Such polymers have a variety of beneficial properties such as biodegradability and biocompatibility, they are readily available on large scale and at low cost. As the amount of fossil fuels decrease, their application becomes more interesting even if characterization is in many cases more challenging due to structural complexity, either by broad distribution of their molecular weights (polysaccharides, polyesters, lignin) or by complex structure (proteins, lignin). This review summarizes different sources and methods for the preparation of biopolymer-based nanoparticle systems for various applications. PMID:25101259

  16. Antibacterial polymer coatings.

    SciTech Connect

    Wilson, Mollye C.; Allen, Ashley N.; Barnhart, Meghan; Tucker, Mark David; Hibbs, Michael R.

    2009-09-01

    A series of poly(sulfone)s with quaternary ammonium groups and another series with aldehyde groups are synthesized and tested for biocidal activity against vegetative bacteria and spores, respectively. The polymers are sprayed onto substrates as coatings which are then exposed to aqueous suspensions of organisms. The coatings are inherently biocidal and do not release any agents into the environment. The coatings adhere well to both glass and CARC-coated coupons and they exhibit significant biotoxicity. The most effective quaternary ammonium polymers kills 99.9% of both gram negative and gram positive bacteria and the best aldehyde coating kills 81% of the spores on its surface.

  17. Polymer infiltration studies

    NASA Technical Reports Server (NTRS)

    Marchello, Joseph M.

    1995-01-01

    Polymer infiltration investigations were directed toward development of methods by which to produce advanced composite material for automated part fabrication utilizing textile and robotic technology in the manufacture of subsonic and supersonic aircraft. Significant progress was made during the project on the preparation of carbon fiber composites using advanced polymer resins. The findings and results of the project are summarized in the attached paper entitled 'Powder-Coated Towpreg: Avenues to Near Net Shape Fabrication of High Performance Composite.' Also attached to this report is the second of two patent applications submitted as a result of these studies.

  18. Computer modeling of polymers

    NASA Technical Reports Server (NTRS)

    Green, Terry J.

    1988-01-01

    A Polymer Molecular Analysis Display System (p-MADS) was developed for computer modeling of polymers. This method of modeling allows for the theoretical calculation of molecular properties such as equilibrium geometries, conformational energies, heats of formations, crystal packing arrangements, and other properties. Furthermore, p-MADS has the following capabilities: constructing molecules from internal coordinates (bonds length, angles, and dihedral angles), Cartesian coordinates (such as X-ray structures), or from stick drawings; manipulating molecules using graphics and making hard copy representation of the molecules on a graphics printer; and performing geometry optimization calculations on molecules using the methods of molecular mechanics or molecular orbital theory.

  19. Polymer infiltration studies

    NASA Technical Reports Server (NTRS)

    Marchello, Joseph M.

    1991-01-01

    Progress was made on the preparation of carbon fiber composites using advanced polymer resins. Processes reported include powder towpreg process, weaving towpreg made from dry powder prepreg, composite from powder coated towpreg, and toughening of polyimide resin (PMR) composites by semi-interpenetrating networks. Several important areas of polymer infiltration into fiber bundles will be researched. Preparation to towpreg for textile preform weaving and braiding and for automated tow placement is a major goal, as are the continued development of prepregging technology and the various aspects of composite part fabrication.

  20. Irreversibility and Polymer Adsorption

    NASA Astrophysics Data System (ADS)

    O'Shaughnessy, Ben; Vavylonis, Dimitrios

    2003-02-01

    Physisorption or chemisorption from dilute polymer solutions often entails irreversible polymer-surface bonding. We present a theory of the resultant nonequilibrium layers. While the density profile and loop distribution are the same as for equilibrium layers, the final layer comprises a tightly bound inner part plus an outer part whose chains make only fN surface contacts where N is chain length. The contact fractions f follow a broad distribution, P(f)˜f-4/5, in rather close agreement with strong physisorption experiments [

    H. M. Schneider et al., LangmuirLANGD50743-7463 12, 994 (1996)
    ].

  1. Shape memory polymer foams

    NASA Astrophysics Data System (ADS)

    Santo, Loredana

    2016-02-01

    Recent advances in shape memory polymer (SMP) foam research are reviewed. The SMPs belong to a new class of smart polymers which can have interesting applications in microelectromechanical systems, actuators and biomedical devices. They can respond to specific external stimulus changing their configuration and then remember the original shape. In the form of foams, the shape memory behaviour can be enhanced because they generally have higher compressibility. Considering also the low weight, and recovery force, the SMP foams are expected to have great potential applications primarily in aerospace. This review highlights the recent progress in characterization, evaluation, and proposed applications of SMP foams mainly for aerospace applications.

  2. Composite solid polymer electrolyte membranes

    SciTech Connect

    Formato, Richard M.; Kovar, Robert F.; Osenar, Paul; Landrau, Nelson; Rubin, Leslie S.

    2006-05-30

    The present invention relates to composite solid polymer electrolyte membranes (SPEMs) which include a porous polymer substrate interpenetrated with an ion-conducting material. SPEMs of the present invention are useful in electrochemical applications, including fuel cells and electrodialysis.

  3. A Course in Polymer Processing.

    ERIC Educational Resources Information Center

    Soong, David S.

    1985-01-01

    A special-topics course in polymer processing has acquired regular course status. Course goals, content (including such new topics as polymer applications in microelectronics), and selected term projects are described. (JN)

  4. Living in the Polymer Age.

    ERIC Educational Resources Information Center

    Markle, Sandra

    1989-01-01

    A number of hands-on science activities are suggested to acquaint children with the variety and properties of polymers. Common polymers are listed; individual and group activities are described; and a reproducible worksheet is included. (IAH)

  5. An overview of degradable polymers

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Many degradable polymers are being investigated for research purpose or for possible commercial use. This overview provides a listing of the more important degradable polymers and their mechanisms of action. Some application areas, particularly in packaging, housewares, personal care, biomaterials, ...

  6. An overview of degradable polymers

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Many degradable polymers are being investigated for research purpose or for possible commercial use. This overview provides a listing of the more important degradable polymers and their mechanisms of action. Some application areas, particularly in packaging, housewares, personal care, biomaterials...

  7. Composite solid polymer electrolyte membranes

    DOEpatents

    Formato, Richard M.; Kovar, Robert F.; Osenar, Paul; Landrau, Nelson; Rubin, Leslie S.

    2001-06-19

    The present invention relates to composite solid polymer electrolyte membranes (SPEMs) which include a porous polymer substrate interpenetrated with an ion-conducting material. SPEMs of the present invention are useful in electrochemical applications, including fuel cells and electrodialysis.

  8. Synthetic Metal-Containing Polymers

    NASA Astrophysics Data System (ADS)

    Manners, Ian

    2004-04-01

    The development of the field of synthetic metal-containing polymers - where metal atoms form an integral part of the main chain or side group structure of a polymer - aims to create new materials which combine the processability of organic polymers with the physical or chemical characteristics associated with the metallic element or complex. This book covers the major developments in the synthesis, properties, and applications of synthetic metal-containing macromolecules, and includes chapters on the preparation and characterization of metal-containing polymers, metallocene-based polymers, rigid-rod organometallic polymers, coordination polymers, polymers containing main group metals, and also covers dendritic and supramolecular systems. The book describes both polymeric materials with metals in the main chain or side group structure and covers the literature up to the end of 2002.

  9. Shape memory polymer medical device

    DOEpatents

    Maitland, Duncan; Benett, William J.; Bearinger, Jane P.; Wilson, Thomas S.; Small, IV, Ward; Schumann, Daniel L.; Jensen, Wayne A.; Ortega, Jason M.; Marion, III, John E.; Loge, Jeffrey M.

    2010-06-29

    A system for removing matter from a conduit. The system includes the steps of passing a transport vehicle and a shape memory polymer material through the conduit, transmitting energy to the shape memory polymer material for moving the shape memory polymer material from a first shape to a second and different shape, and withdrawing the transport vehicle and the shape memory polymer material through the conduit carrying the matter.

  10. Synthesis of thermally stable polymers

    NASA Technical Reports Server (NTRS)

    Butler, G. B.

    1978-01-01

    The reaction of bis triazo linediones with divinyl esters and substituted styrenes was investigated. Twenty new polymers were derived via reaction of two previously synthesized bis triazol linediones and four new bis atriazol linediones with eight styrenes. The structure and polymer properties of these thermally stable polymers was examined. The reaction of triazo linediones with enol esters was also considered.

  11. Polymer Thermoelectric Generators: Device Considerations

    NASA Astrophysics Data System (ADS)

    Yee, Shannon

    2014-03-01

    Recent control of the transport properties in polymers has encouraged the development of polymer thermoelectric (TE) devices. Polymer TEs are thought to be less expensive and more scalable than their inorganic counterparts. The cost of the raw material is less and polymer TEs can leverage the large areal manufacturing technique established by the plastics industry. Additionally, while the overall ZT of polymer TEs appears attractive, individual polymer properties have a very different scale than their inorganic counterparts (i.e., the thermal conductivity and electrical conductivity are approximately one and two orders of magnitude smaller, respectively). Furthermore, the majority of TE measurements on polymers have been limited to thin-films where traditional TE materials are measured in bulk. So why should it be expected that polymer TE devices resemble traditional TE devices? Given the uniqueness of polymers, different device architectures are proposed that can leverage the unique strengths of polymer films. It will be shown that by logically considering device requirements, new polymer TE devices have non-linear features that are more attractive than linear inorganic TE devices. This leads to very different device optimizations that favor polymer TEs.

  12. New polymers for phase partitioning

    NASA Technical Reports Server (NTRS)

    Harris, J. M.

    1981-01-01

    The synthesizing of several polyethylene glycols having crown ethers attached is reported. This work led to the identification of three new polymer types which promise to be more effective at selectively binding specific cell types. Work was completed on identification of chemical properties of the new polymer crowns and on development of new techniques for determination of polymer-phase composition.

  13. Viscoelastic Properties of Polymer Blends

    NASA Technical Reports Server (NTRS)

    Hong, S. D.; Moacanin, J.; Soong, D.

    1982-01-01

    Viscosity, shear modulus and other viscoelastic properties of multicomponent polymer blends are predicted from behavior of individual components, using a mathematical model. Model is extension of two-component-blend model based on Rouse-Bueche-Zimm theory of polymer viscoelasticity. Extension assumes that probabilities of forming various possible intracomponent and intercomponent entanglements among polymer molecules are proportional to relative abundances of components.

  14. Semi-Interpenetrating Polymer Networks

    NASA Technical Reports Server (NTRS)

    St. Clair, T. L.; Egli, A. O.

    1987-01-01

    Desirable qualities achieved by "networking" aromatic and addition polyimides. Novel semi-interpenetrating network (semi-ipn) prepared from two types of polyimides. Semi-ipn results when linear polymer synthesized in presence of cross-linked polymer or vice-versa. Semi-ipn attains certain properties better than those of either polymer alone.

  15. Aerogel/polymer composite materials

    NASA Technical Reports Server (NTRS)

    Williams, Martha K. (Inventor); Smith, Trent M. (Inventor); Fesmire, James E. (Inventor); Roberson, Luke B. (Inventor); Clayton, LaNetra M. (Inventor)

    2010-01-01

    The invention provides new composite materials containing aerogels blended with thermoplastic polymer materials at a weight ratio of aerogel to thermoplastic polymer of less than 20:100. The composite materials have improved thermal insulation ability. The composite materials also have better flexibility and less brittleness at low temperatures than the parent thermoplastic polymer materials.

  16. Solid polymer electrolyte compositions

    DOEpatents

    Garbe, James E.; Atanasoski, Radoslav; Hamrock, Steven J.; Le, Dinh Ba

    2001-01-01

    An electrolyte composition is featured that includes a solid, ionically conductive polymer, organically modified oxide particles that include organic groups covalently bonded to the oxide particles, and an alkali metal salt. The electrolyte composition is free of lithiated zeolite. The invention also features cells that incorporate the electrolyte composition.

  17. High temperature polymer concrete

    DOEpatents

    Fontana, J.J.; Reams, W.

    1984-05-29

    This invention is concerned with a polymer concrete composition, which is a two-component composition useful with many bases including metal. Component A, the aggregate composition, is broadly composed of silica, silica flour, portland cement, and acrylamide, whereas Component B, which is primarily vinyl and acrylyl reactive monomers, is a liquid system.

  18. Selecting the right polymer.

    PubMed

    Olson, C M

    2009-10-01

    Choosing the correct polymer for a medical device requires a comprehensive look at many aspects of performance and economy. This decision-making process is illustrated here with approaches to choosing materials for an injection moulded steam sterilisation tray for surgical instruments and goods. PMID:20302136

  19. Overview on energetic polymers

    SciTech Connect

    Boileau, J.

    1996-07-01

    Energetic materials for missiles, gun munitions or pyrotechnic devices often are mixtures in a biphasic form, with a filler and a binder. To satisfy the user needs, an analysis of functional requirements together with constraints (safety, vulnerability, aging, environment, disposal, price) is useful to choose a convenient binder. From this point of view numerous synthetic energetic polymers proposed or developed as binders are reviewed with regard to their syntheses, processing, properties and possible uses. These polymers contain explosophore groups: C-NO{sub 2} aliphatic or aromatic, ONO{sub 2}, NNO{sub 2}, NF{sub 2} and N{sub 3}. Some research projects are suggested. Among them in the list of published polymers, following a NIMIC (NATO) suggestion, note the reason of a development interruption. Some dinitropolystyrene-polyvinyl nitrate mixtures or copolymers could exhibit interesting properties. For unknown reasons, some mixtures of crystalline filler with polymer binder, generally in a biphasic form, may also be monophasic for a same composition. What properties are modified between both forms (e.g. combustion mechanisms, erosion, ideal character of the detonation)? It is also interesting to pursue a newly open route to thermo-plastic elastomers. 50 refs., 1 tab.

  20. Durable metallized polymer mirror

    DOEpatents

    Schissel, Paul O.; Kennedy, Cheryl E.; Jorgensen, Gary J.; Shinton, Yvonne D.; Goggin, Rita M.

    1994-01-01

    A metallized polymer mirror construction having improved durability against delamination and tunneling, comprising: an outer layer of polymeric material; a metal oxide layer underlying the outer layer of polymeric material; a silver reflective layer underneath the metal oxide layer; and a layer of adhesive attaching the silver layer to a substrate.

  1. Durable metallized polymer mirror

    DOEpatents

    Schissel, P.O.; Kennedy, C.E.; Jorgensen, G.J.; Shinton, Y.D.; Goggin, R.M.

    1994-11-01

    A metallized polymer mirror construction is disclosed having improved durability against delamination and tunneling, comprising: an outer layer of polymeric material; a metal oxide layer underlying the outer layer of polymeric material; a silver reflective layer underneath the metal oxide layer; and a layer of adhesive attaching the silver layer to a substrate. 6 figs.

  2. Self-sterilizing polymers

    NASA Technical Reports Server (NTRS)

    Tulis, J. J.; Daley, D. J.; Phillips, G. B.

    1973-01-01

    Addition of approximately 1% paraformaldehyde to room-temperature-vulcanizing potting polymer results in effective, controllable germicide. When heated above ambient temperatures, paraformaldehyde releases dry formaldehyde, which can penetrate enclosed areas and packages, will not damage material, and leaves no permanent residue.

  3. Cyclic polymers from alkynes.

    PubMed

    Roland, Christopher D; Li, Hong; Abboud, Khalil A; Wagener, Kenneth B; Veige, Adam S

    2016-08-01

    Cyclic polymers have dramatically different physical properties compared with those of their equivalent linear counterparts. However, the exploration of cyclic polymers is limited because of the inherent challenges associated with their synthesis. Conjugated linear polyacetylenes are important materials for electrical conductivity, paramagnetic susceptibility, optical nonlinearity, photoconductivity, gas permeability, liquid crystallinity and chain helicity. However, their cyclic analogues are unknown, and therefore the ability to examine how a cyclic topology influences their properties is currently not possible. We have solved this challenge and now report a tungsten catalyst supported by a tetraanionic pincer ligand that can rapidly polymerize alkynes to form conjugated macrocycles in high yield. The catalyst works by tethering the ends of the polymer to the metal centre to overcome the inherent entropic penalty of cyclization. Gel-permeation chromatography, dynamic and static light scattering, viscometry and chemical tests are all consistent with theoretical predictions and provide unambiguous confirmation of a cyclic topology. Access to a wide variety of new cyclic polymers is now possible by simply choosing the appropriate alkyne monomer. PMID:27442285

  4. Cyclic polymers from alkynes

    NASA Astrophysics Data System (ADS)

    Roland, Christopher D.; Li, Hong; Abboud, Khalil A.; Wagener, Kenneth B.; Veige, Adam S.

    2016-08-01

    Cyclic polymers have dramatically different physical properties compared with those of their equivalent linear counterparts. However, the exploration of cyclic polymers is limited because of the inherent challenges associated with their synthesis. Conjugated linear polyacetylenes are important materials for electrical conductivity, paramagnetic susceptibility, optical nonlinearity, photoconductivity, gas permeability, liquid crystallinity and chain helicity. However, their cyclic analogues are unknown, and therefore the ability to examine how a cyclic topology influences their properties is currently not possible. We have solved this challenge and now report a tungsten catalyst supported by a tetraanionic pincer ligand that can rapidly polymerize alkynes to form conjugated macrocycles in high yield. The catalyst works by tethering the ends of the polymer to the metal centre to overcome the inherent entropic penalty of cyclization. Gel-permeation chromatography, dynamic and static light scattering, viscometry and chemical tests are all consistent with theoretical predictions and provide unambiguous confirmation of a cyclic topology. Access to a wide variety of new cyclic polymers is now possible by simply choosing the appropriate alkyne monomer.

  5. Rippling of polymer nanofibers.

    PubMed

    Wu, Xiang-Fa; Kostogorova-Beller, Yulia Y; Goponenko, Alexander V; Hou, Haoqing; Dzenis, Yuris A

    2008-12-01

    This paper studies the evolution mechanism of surface rippling in polymer nanofibers under axial stretching. This rippling phenomenon has been detected in as-electrospun polyacrylonitrile in recent single-fiber tension tests, and in electrospun polyimide nanofibers after imidization. We herein propose a one-dimensional nonlinear elastic model that takes into account the combined effect of surface tension and nonlinear elasticity during the rippling initiation and its evolution in compliant polymer nanofibers. The polymer nanofiber is modeled as an incompressible, isotropically hyperelastic Mooney-Rivlin solid. The fiber geometry prior to rippling is considered as a long circular cylinder. The governing equation of surface rippling is established through linear perturbation of the static equilibrium state of the nanofiber subjected to finite axial prestretching. The critical stretch and ripple wavelength are determined in terms of surface tension, elastic property, and fiber radius. Numerical examples are demonstrated to examine these dependencies. In addition, a critical fiber radius is determined, below which the polymer nanofibers are intrinsically unstable. The present model, therefore, is capable of predicting the rippling condition in compliant nanofibers, and can be further used as a continuum mechanics approach for the study of surface instability and nonlinear wave propagation in compliant fibers and wires at the nanoscale. PMID:19256861

  6. Phosphazene Polymers Containing Carborane

    NASA Technical Reports Server (NTRS)

    Fewell, L. L.; Parker, J. A.; Basi, R. J.

    1986-01-01

    Addition of carborane increases thermal stability. Carborane-substituted polyphosphazenes prepared by thermal polymerization of phenylcarbonyl-pentachlorocyclotriphosphazene followed by reaction with sodium trifluoroethoxide to replace remaining chlorine atoms with trifluoroethoxy groups. Improved polymers offer high char yields and resistance to hydrolysis.

  7. Metal-Polymer Nanocomposites

    NASA Astrophysics Data System (ADS)

    Nicolais, Luigi; Carotenuto, Gianfranco

    2004-09-01

    A unique guide to an essential area of nanoscience Interest in nano-sized metals has increased greatly due to their special characteristics and suitability for a number of advanced applications. As technology becomes more refined-including the ability to effectively manipulate and stabilize metals at the nanoscale-these materials present ever-more workable solutions to a growing range of problems. Metal-Polymer Nanocomposites provides the first guide solely devoted to the unique properties and applications of this essential area of nanoscience. It offers a truly multidisciplinary approach, making the text accessible to readers in physical, chemical, and materials science as well as areas such as engineering and topology. The thorough coverage includes: * The chemical and physical properties of nano-sized metals * Different approaches to the synthesis of metal-polymer nanocomposites (MPN) * Advanced characterization techniques and methods for study of MPN * Real-world applications, including color filters, polarizers, optical sensors, nonlinear optical devices, and more * An extensive list of references on the topics covered A unique, cutting-edge resource for a vital area of nanoscience development, Metal-Polymer Nanocomposites is an invaluable text for students and practitioners of materials science, engineering, polymer science, chemical engineering, electrical engineering, and optics.

  8. Water soluble conductive polymers

    SciTech Connect

    Aldissi, M.

    1989-11-14

    This patent describes polymers which are soluble in water and are electrically conductive. The monomer repeat unit is a thiophene or pyrrole molecule having an alkyl group substituted for the hydrogen atom located in the beta position of the thiophene or pyrrole ring and having a surfactant molecule at the end of the alkyl chain. Polymers of this class having 8 or more carbon atoms in the alkyl chain exhibit liquid crystalline behavior, resulting in high electrical anisotropy. The monomer-to-monomer bonds are located between the carbon atoms which are adjacent to the sulfur or nitrogen atoms. The number of carbon atoms in the alkyl group may vary from 1 to 20 carbon atoms. The surfactant molecule consists of a sulfonate group, or a sulfate group, or a carboxylate group, and hydrogen or an alkali metal. Negative ions from a supporting electrolyte which may be used in the electrochemical synthesis of a polymer may be incorporated into the polymer during the synthesis and serve as a dopant to increase the conductivity.

  9. Polymer infiltration studies

    NASA Technical Reports Server (NTRS)

    Marchello, Joseph M.

    1992-01-01

    The preparation is reported of carbon fiber composites using advanced polymer resins. Current and ongoing research activities include: powder towpreg process; weaving, braiding and stitching dry powder prepreg; advanced tow placement; and customized ATP towpreg. The goal of these studies is to produce advanced composite materials for automated part fabrication using textile and robotics technology in the manufacture of subsonic and supersonic aircraft.

  10. Mesoporous carbons and polymers

    DOEpatents

    Bell, William; Dietz, Steven

    2001-01-01

    A mesoporous material prepared by polymerizing a resorcinol/formaldehyde system from an aqueous solution containing resorcinol, formaldehyde and a surfactant and optionally pyrolyzing the polymer to form a primarily carbonaceous solid. The material has an average pore size between 4 and 75 nm and is suitable for use in liquid-phase surface limited applications, including sorbent, catalytic, and electrical applications.

  11. The Epidemiology of Hip and Major Osteoporotic Fractures in a Dutch Population of Community-Dwelling Elderly: Implications for the Dutch FRAX® Algorithm

    PubMed Central

    Klop, Corinne; Welsing, Paco M. J.; Leufkens, Hubert G. M.; Elders, Petra J. M.; Overbeek, Jetty A.; van den Bergh, Joop P.; Bijlsma, Johannes W. J.; de Vries, Frank

    2015-01-01

    Background Incidence rates of non-hip major osteoporotic fractures (MOF) remain poorly characterized in the Netherlands. The Dutch FRAX® algorithm, which predicts 10-year probabilities of hip fracture and MOF (first of hip, humerus, forearm, clinical vertebral), therefore incorporates imputed MOF rates. Swedish incidence rate ratios for hip fracture to MOF (Malmo 1987–1996) were used to perform this imputation. However, equality of these ratios between countries is uncertain and recent evidence is scarce. Aims were to estimate incidence rates of hip fracture and MOF and to compare observed MOF rates to those predicted by the imputation method for the Netherlands. Methods Using hospitalisation and general practitioner records from the Dutch PHARMO Database Network (2002–2011) we calculated age-and-sex-specific and age-standardized incidence rates (IRs) of hip and other MOFs (humerus, forearm, clinical vertebral) and as used in FRAX®. Observed MOF rates were compared to those predicted among community-dwelling individuals ≥50 years by the standardized incidence ratio (SIR; 95% CI). Results Age-standardized IRs (per 10,000 person-years) of MOF among men and women ≥50 years were 25.9 and 77.0, respectively. These numbers were 9.3 and 24.0 for hip fracture. Among women 55–84 years, observed MOF rates were significantly higher than predicted (SIR ranged between 1.12–1.50, depending on age). In men, the imputation method performed reasonable. Conclusion Observed MOF incidence was higher than predicted for community-dwelling women over a wide age-range, while it agreed reasonable for men. As miscalibration may influence treatment decisions, there is a need for confirmation of results in another data source. Until then, the Dutch FRAX® output should be interpreted with caution. PMID:26633011

  12. Food insecurity among Dutch food bank recipients: a cross-sectional study

    PubMed Central

    Neter, Judith E; Dijkstra, S Coosje; Visser, Marjolein; Brouwer, Ingeborg A

    2014-01-01

    Objective To determine the prevalence of (very) low food security among Dutch food bank recipients, and to identify potential demographic, lifestyle and nutrition-related factors associated with (very) low food security. Setting 11 of 135 Dutch food banks were selected throughout the Netherlands. Participants 251 Dutch food bank recipients participated in the study (93 men and 158 women). Inclusion criteria for participation were: (1) at least 18 years of age, (2) sufficiently fluent in Dutch to participate in oral and written interviews, (3) recipient of a Dutch food bank for at least 1 month and (4) collect own food parcel at the food bank. A single member per household was included. Primary outcome Level of food security. Results The prevalence of food insecurity was 72.9% (N=183), of which 40.4% (N=74) reported very low food security. Of the very low food secure participants, 56.8% (N=42) reported they were ever hungry but did not eat because they could not afford enough food in the previous 3 months. Adjusted multinomial logistic regression analyses showed that households without children were less likely to experience low food security (OR 0.39 (95% CI 0.18 to 0.88)) and men (OR 0.24 (95% CI 0.11 to 0.51)) were less likely to experience very low food security, while low-educated recipients (OR 5.05 (95% CI 1.37 to 18.61)) were more likely to experience very low food security. Furthermore, recipients with high satisfaction with overall food intake (OR 0.46 (95% CI 0.27 to 0.78)), high perceived healthiness of overall food intake (OR 0.34 (95% CI 0.19 to 0.62)) or high self-efficacy of eating healthy (OR 0.62 (95% CI 0.40 to 0.96)) were less likely to experience very low food security. Conclusions Our study showed high prevalence rates of food insecurity among Dutch food bank recipients, and identified subgroups at increased risk of food insecurity. More research is urgently needed on the underlying determinants of food insecurity and the effectiveness of

  13. [The foundation of the Dutch Society for Tropical Medicine: an affair of national importance].

    PubMed

    van Bergen, Leo

    2009-01-01

    The 'Nederlandsche Vereeniging voor Tropische Geneeskunde' (Dutch Society for Tropical Medicine--in short: NVTG) was founded in 1907, a time not only of colonial expansion, but also a time in which the economic interest of the Dutch East-Indies for The Netherlands grew exceptionally. This had its effect on the motivations behind medical aid. Hygienic measures were financially backed because healthy workers had a positive effect on profits. This atmosphere of economic interest and political-military expansion had its effect on the foundation of the NVTG as well. Colonialism was generally approved of, and the goal of the society apart from sociability motives--was to support research into illnesses torturing mainly the Dutch colonies. This was in line with the reasoning that the colonies were rightfully governed by the Netherlands, because the peoples living there had proven not to be able to look after themselves in a proper manner. The foundation of the Society should have been a part of the foundation of an international society for tropical medicine, but this failed. Although internationalism generally was seen as an important feature of science and certainly of medical science, it is not strange this was not seen as a major problem. For it was national and not international reasons that had led to founding the Dutch society. It was the Dutch position as a colonial power that had convinced Dutch tropical doctors a society should be called into being. A generally shared spirit of internationalism had little to do with this unless internationalism is defined as: what others have, we need to have as well, and let us see in international conferences what could be of national benefit. That nevertheless this spirit of internationalism--and not nationalism--is commonly hailed as the main reason behind the foundation, is probably due to the fact that around 1900 nationalism was such a normal state of mind and so fully incorporated in man's way of thinking and acting

  14. Reliability and validity of the Dutch version of the Behavioural Status Index: a nurse-rated forensic assessment tool.

    PubMed

    Chakhssi, Farid; de Ruiter, Corine; Bernstein, David

    2010-03-01

    The Behavioural Status Index (BEST-Index) has been introduced into Dutch forensic psychiatry to measure change in risk level of future violence. The BEST-Index is a structured observational measure that assesses aggressive behavior, degree of insight, social skills, self-care, and work and leisure skills during inpatient treatment. Thus far, limited information regarding the psychometric properties of the Dutch version of the BEST-Index is available. The present study examines the reliability and validity of the Dutch BEST-Index in a sample of 291 mentally disordered offenders admitted to a forensic psychiatric hospital. Interrater reliability was investigated in a sample of 182 raters. Findings show that the Dutch BEST-Index can be used reliably and is significantly associated with risk of future violence and institutional aggression. Furthermore, this study revealed a different and clearer factor structure compared with the original one. Further research is needed to examine how these derived factors predict future recidivism. PMID:19700739

  15. Logique des langues europeennes VII: Le Neerlandais et le polder (Logic of European Languages VII: Dutch and the Polder).

    ERIC Educational Resources Information Center

    Van Lier, Henri

    1990-01-01

    Views the Dutch language as analogous to the polder typical of the Netherlands, an area of low-lying land reclaimed from a body of water and protected by dikes. Phonological, morphological, syntactic, semantic, and stylistic analyses are presented. (MSE)

  16. Gel polymer electrolytes for batteries

    DOEpatents

    Balsara, Nitash Pervez; Eitouni, Hany Basam; Gur, Ilan; Singh, Mohit; Hudson, William

    2014-11-18

    Nanostructured gel polymer electrolytes that have both high ionic conductivity and high mechanical strength are disclosed. The electrolytes have at least two domains--one domain contains an ionically-conductive gel polymer and the other domain contains a rigid polymer that provides structure for the electrolyte. The domains are formed by block copolymers. The first block provides a polymer matrix that may or may not be conductive on by itself, but that can soak up a liquid electrolyte, thereby making a gel. An exemplary nanostructured gel polymer electrolyte has an ionic conductivity of at least 1.times.10.sup.-4 S cm.sup.-1 at 25.degree. C.

  17. Supramolecular Polymers in Aqueous Media.

    PubMed

    Krieg, Elisha; Bastings, Maartje M C; Besenius, Pol; Rybtchinski, Boris

    2016-02-24

    This review discusses one-dimensional supramolecular polymers that form in aqueous media. First, naturally occurring supramolecular polymers are described, in particular, amyloid fibrils, actin filaments, and microtubules. Their structural, thermodynamic, kinetic, and nanomechanical properties are highlighted, as well as their importance for the advancement of biologically inspired supramolecular polymer materials. Second, five classes of synthetic supramolecular polymers are described: systems based on (1) hydrogen-bond motifs, (2) large π-conjugated surfaces, (3) host-guest interactions, (4) peptides, and (5) DNA. We focus on recent studies that address key challenges in the field, providing mechanistic understanding, rational polymer design, important functionality, robustness, or unusual thermodynamic and kinetic properties. PMID:26727633

  18. Conducting Polymers for Neutron Detection

    SciTech Connect

    Kimblin, Clare; Miller, Kirk; Vogel, Bob; Quam, Bill; McHugh, Harry; Anthony, Glen; Mike, Grover

    2007-12-01

    Conjugated polymers have emerged as an attractive technology for large-area electronic applications. As organic semiconductors, they can be used to make large-area arrays of diodes or transistors using fabrication techniques developed for polymer coatings, such as spraying and screen-printing. We have demonstrated both neutron and alpha detection using diodes made from conjugated polymers and have done preliminary work to integrate a boron carbide layer into the conventional polymer device structure to capture thermal neutrons. The polymer devices appear to be insensitive to gamma rays, due to their small physical thickness and low atomic number.

  19. Polymers for Drug Delivery Systems

    PubMed Central

    Liechty, William B.; Kryscio, David R.; Slaughter, Brandon V.; Peppas, Nicholas A.

    2012-01-01

    Polymers have played an integral role in the advancement of drug delivery technology by providing controlled release of therapeutic agents in constant doses over long periods, cyclic dosage, and tunable release of both hydrophilic and hydrophobic drugs. From early beginnings using off-the-shelf materials, the field has grown tremendously, driven in part by the innovations of chemical engineers. Modern advances in drug delivery are now predicated upon the rational design of polymers tailored for specific cargo and engineered to exert distinct biological functions. In this review, we highlight the fundamental drug delivery systems and their mathematical foundations and discuss the physiological barriers to drug delivery. We review the origins and applications of stimuli-responsive polymer systems and polymer therapeutics such as polymer-protein and polymer-drug conjugates. The latest developments in polymers capable of molecular recognition or directing intracellular delivery are surveyed to illustrate areas of research advancing the frontiers of drug delivery. PMID:22432577

  20. Dissolving Polymers in Ionic Liquids.

    NASA Astrophysics Data System (ADS)

    Hoagland, David; Harner, John

    2009-03-01

    Dissolution and phase behavior of polymers in ionic liquids have been assessed by solution characterization techniques such as intrinsic viscosity and light scattering (static and dynamic). Elevated viscosity proved the greatest obstacle. As yet, whether principles standard to conventional polymer solutions apply to ionic liquid solutions is uncertain, especially for polymers such as polyelectrolytes and hydrophilic block copolymers that may specifically interact with ionic liquid anions or cations. For flexible polyelectrolytes (polymers releasing counterions into high dielectric solvents), characterization in ionic liquids suggests behaviors more typical of neutral polymer. Coil sizes and conformations are approximately the same as in aqueous buffer. Further, several globular proteins dissolve in a hydrophilic ionic liquid with conformations analogous to those in buffer. General principles of solubility, however, remain unclear, making predictions of which polymer dissolves in which ionic liquid difficult; several otherwise intractable polymers (e.g., cellulose, polyvinyl alcohol) dissolve and can be efficiently functionalized in ionic liquids.