Science.gov

Sample records for efeitos da isoflavona

  1. Efeito do Solo do Materias Organicos E do Adubo Formula 4N:14P:8K Para Producao DA Batata (Solanum tuberosum L.) Semente Pre-Basica no Casa de Vegetacao

    NASA Astrophysics Data System (ADS)

    László, Márton

    2010-05-01

    Widely well know that the potato is an important vegetable crop at Brazíl. Plant grown on about 173.000 ha, with total yield of 2.6 million tons year-1. The average yield is about 15 t ha-1. This level is very low because degeneration of crop is rapid under high temperature and high viruses pressure. Therefore seed potato propagation and production is principal on consumption potato production. This is why we found it necessary to develop it. The latossolo vermelho soil-farmyard manure- burnt rice straw-fertilizer 4N:14P:8K greenhouse pot trial was set up at the National Vegetable Crops Research Center, Brasília-DF, Brazíl in 1990. The methods of the experiments were soil x farmyard manure x burnt rice straw, soil x 4N:14P:8K fertilizer and soil x farmyard manure x burnt rice straw x 4N:14P:8K fertilizer on randomized block design in total 29 combination of treatments in 5, 5 and 3 repetitions with in a total parcel of 116. According to chemical analysis of the a., soil, b., farmyard manure and c., burnt rice straw the agrochemistry parameters were as follows: a., latossolo vermelho soil: CaCO3 0.3-0.7%, humo 0.9-1.0%, pH (H2O) 5.3, pH (KCl) 4.5, AL- P2O5 3.2-3.5 mg kg-1, AL- K2O 180 mg kg-1, Mg (KCl) 70 mg kg-1, EDTA-Zn 0.5-0.8 mg kg-1, EDTA-Cu 0.5-0.6 mg kg-1, b., farmyard manure: N 1.8 g kg-1, P2O5 2.0 g kg-1, K2O 4.0 g kg-1, c., burnt rice straw: N 0.8 g kg-1, P2O5 7.0 g kg-1, K2O 4.5 g kg-1. The experimental datas were estimated by analysis of variance, ANOVA and MANOVA. The main conclusions were as follows: 1. Mixture of 80% latossolo vermelho, 10% burnt rice straw and 10% farmyard manure were shown best performance on seed potato productivity. The piece of tubers with a 0-20 mm (consumption seeds) was increased by 77%. 2. Total seed potato number was reached maximum at 10.8 g pot-1 4N:14P:8K fertilizer regarding to average of treatments with a 33%. 3. Dry biomassa production plant-1 was decreased by high dose of 4N:14P:8K fertilizer (18.0 g pot-1) with a hard effect (57%). Our results are shown that it was possible developing of the seed potato production under tropical greenhouse conditions by optimalised soil-organic matter-fertilizer system. This datas should be as indicators to sustainable field potato advisory systems. Keywords: potato (Solanum tuberosum L.), greenhouse, latossolo vermelho soil, farmyard manure, burnt rice straw, 4N:14P:8K fertilizer, sustainability, yield RESUMO A batata é atualmente uma das hortaliças de maior importância no Brasíl. Nos conduzirémos os três experimentos para aumentár-se do produção e produtividade da batata (Solanum tuberosum L.) semente pré- básica no casa de vegetação da Brazília-DF, no Empresa Brasileira de Pesquisa Agropecuaria- Centro Nacional de Pesquisas de Hortaliças no 1990. Os três experimentos (latossolo vermelho novo x esterco de curral x palha de arroz queimado, latossolo vermelho novo x adubo 4:14:8 NPK, latossolo vermelho novo x esterco de curral x palha de arroz queimado x adubo 4:14:8 NPK) no casa de vegetação foram conduzidos com total 29 combinações, no 5-5-3 repetições com total parcelas de 116. Os resultados foram submetidos a analise de variáncia, ANOVA e MANOVA. Nossos principal resultados estam apresentándo abaixo. 1. A mistura de 80% latossolo vermelho novo, 10% palha de arroz queimado e 10% de esterco de curral, apresentou os maiores valores para numero de tuberculos com 0-20 mm, peso total de tuberculos com 0-20 mm e peso total de tuberculos por vaso. 2. Há um efeito grande crescente das doses de 4N:14P:8K nos caracteres observados. 3. Analise-se do latossolo vermelho novo x esterco de curral x palha de arroz queimado x adubo 4:14:8 NPK experimento os resultados apresentárám-se que entre nas misturas também foi melhor a 80% latossolo vermelho novo, 10% palha de arroz queimado, 10% esterco de curral. Examinando-se 15 fatores, entre 11 casos afirmou-se a mistura como para melhor que a outra mistura. Nossos resultados apresentam- se que possivel aumentar em grande volumens o produção da batata semente pré- básica co

  2. Estudo de não gaussianidade nas anisotropias da RCF medidas Wmap

    NASA Astrophysics Data System (ADS)

    Andrade, A. P. A.; Wuensche, C. A.; Ribeiro, A. L. B.

    2003-08-01

    A investigação do campo de flutuações da Radiação Cósmica de Fundo (RCF) pode oferecer um importante teste para os modelos cosmológicos que descrevem a origem e a evolução das flutuações primordiais. De um lado, apresenta-se o modelo inflacionário que prevê um espectro de flutuações adiabáticas distribuídas segundo uma gaussiana e, de outro, os modelos de defeitos topológicos (dentre outros) que descrevem um mecanismo para a geração de flutuações de isocurvatura que obedecem a uma distribuição não gaussiana. Este trabalho tem como objetivo caracterizar traços do modelo não gaussiano de campo misto (entre flutuações adiabáticas e de isocurvatura) nos mapas do Wilkinson Microwave Anisotropy Probe (WMAP). Simulações das anisotropias da RCF no contexto de mistura indicam traços marcantes na distribuição das flutuações de temperatura, mesmo quando consideradas pequenas contribuições do campo de isocurvatura (da ordem de 0.001). O efeito da mistura entre os campos resulta na transferência de potência de flutuações em escalas angulares intermediárias para flutuações em pequenas escalas angulares. Este efeito pode ser caracterizado pela relação entre as amplitudes dos primeiros picos acústicos no espectro de potência da RCF. Neste trabalho, investigamos a contribuição do campo de isocurvatura, no contexto de mistura, sobre as observações recentes da RCF realizadas pelo WMAP. As previsões do modelo de campo misto, uma vez confrontadas com as observações em pequenas escalas angulares, podem ajudar a revelar a natureza das flutuações primordiais.

  3. MONITORAMENTO DA COBERTURA FLORESTAL DA AMAZNIA

    E-print Network

    INPE SOBRE O RELATÓRIO: "INSPEÇÃO DE PONTOS E ÁREAS DO DETER" DA SECRETARIA DE ESTADO DO MEIO AMBIENTE 2008, técnicos do Instituto Nacional de Pesquisas Espaciais (INPE) e da Secretaria de Estado do Meio

  4. Lionardo da Vinci Cantor, Moritz

    E-print Network

    Gertz, Michael

    Lionardo da Vinci Cantor, Moritz Originalveröffentlichung in: Westermanns illustrierte deutsche Vinci Quelle: Westermanns illustrierte deutsche Monatshefte. Band 44 (1878), S. 369-381 Seite 369 ­ 381 Naturwissenschaftler Leo- nardo da Vinci. Er berichtet ¨uber den in Spiegelschrift verfassten Codex atlantico da Vincis

  5. Informativo Ano 1 n 02 Agosto/2013 Lanamento da pedra fundamental da sede da OTCA

    E-print Network

    Como parte da comemoração dos 35 anos do Tratado de Cooperação Amazônica foi lançada, no dia 01 de agosto, a pedra fundamental para a construção da nova sede da OTCA em Brasília. O tratado foi assinado reunião com a OTCA (Organização do Tratado de Cooperação Amazônica) em que foram discutidos os resultados

  6. [da Vinci surgical system].

    PubMed

    Watanabe, Gou; Ishikawa, Norihiro

    2014-07-01

    The da Vinci surgical system was developed by Intuitive Surgical Inc. in the United States as an endoscopic surgical device to assist remote control surgeries. In 1998, the Da Vinci system was first used for cardiothoracic procedures. Currently a combination of robot-assisted internal thoracic artery harvest together with coronary artery bypass grafting (CABG) through a mini-incision (ThoraCAB) or totally endoscopic procedures including anastomoses under robotic assistance (TECAB) are being conducted for the treatment of coronary artery diseases. With the recent advances in catheter interventions, hybrid procedures combining catheter intervention with ThoraCAB or TECAB are anticipated in the future.On the other hand, with the decrease in number of coronary artery bypass surgeries, the share of valvular surgeries is expected to increase in the future. Among them, mitral valvuloplasty for mitral regurgitation is anticipated to be conducted mainly by low-invasive procedures, represented by minimally invasive cardiac surgery( MICS) and robot-assisted surgery. Apart from the intrinsic good surgical view, robotic-assisted systems offer additional advantages of the availability of an amplified view and the easy to observe the mitral valve in the physiological position. Thus, robotic surgical surgeries that make complicated procedures easier are expected to accomplish further developments in the future. Furthermore, while the number of surgeries for atrial septal defects has decreased dramatically following the widespread use of Amplatzer septal occluder, robotic surgery may become a good indication for cases in which the Amplatzer device is not indicated. In Japan, clinical trial of the da Vinci robotic system for heart surgeries has been completed. Statutory approval of the da Vinci system for mitral regurgitation and atrial septal defects is anticipated in the next few years. PMID:25138939

  7. Abundâncias de oxigênio e enxofre nas estrelas de tipo solar da vizinhança solar

    NASA Astrophysics Data System (ADS)

    Requeijo, F.; Porto de Mello, G. F.

    2003-08-01

    Alguns resultados sugerem que o Sol seja 58% mais abundante em oxigênio que o meio interestelar local. Esta anomalia parece estender-se para o carbono e o criptônio. Entre as possíveis explicações deste fenômeno estão: uma supernova de tipo II que tenha enriquecido a nebulosa protosolar, tornando-a superabundante em oxigênio; um episódio de infall de material pobre em metais sobre o disco Galático, diluindo o meio interestelar local ou uma migração dinâmica do Sol de uma órbita mais interna da Galáxia para sua posição atual. A escolha entre estes cenários exige o conhecimento preciso da abundância solar em relação às anãs G da vizinhança. Neste contexto, o oxigênio e enxofre, são elementos-chave por serem ambos produzidos pelas supernovas de tipo II, devendo portanto possuir o mesmo padrão de abundância. Este projeto visa esclarecer qual a posição do Sol na distribuição local de abundâncias de enxofre e oxigênio para uma amostra de estrelas de tipo solar com idades e metalicidades bem conhecidas. Para tal, analisamos espectros de alta resolução e alta relação sinal-ruído nas regiões espectrais de ll 6300, 7774 (O) e l8695 (S). Para o enxofre encontramos que o Sol parece ser uma estrela típica dentre as da vizinhança, e que este elemento não mostra a sobreabundância para baixas metalicidades, já bem estabelecida para o oxigênio. Discutimos as abundâncias do enxofre no contexto da Evolução Química da Galáxia. Apresentamos resultados preliminares muito precisos para a linha proibida do oxigênio l6300 e comparamos estes com os obtidos para o tripleto em l7774. Quantificamos os efeitos não-ETL presentes no tripleto em função dos parâmetros atmosféricos estelares.

  8. Henrique da Rocha Lima.

    PubMed

    Bernardes Filho, Fred; Avelleira, João Carlos Regazzi

    2015-01-01

    Brazilian physician and researcher Henrique da Rocha Lima was born in 1879 in the city of Rio de Janeiro, where he studied medicine and obtained the degree of M.D. in 1901. He specialized in Clinical Medicine in Germany and was the ambassador in European countries of the scientific medicine that emerged from the Oswaldo Cruz Institute in the early twentieth century. Rocha Lima has discovered the causative agent of typhus and had a major contribution to the studies of yellow fever, Chagas disease, Carrión's disease and histoplasmosis. His genius, his research and his discoveries projected his name, and, with it, the image of Brazil in the international scientific scene. PMID:26131867

  9. A importância da poeira e ondas de Alfvén na estabilidade de nuvens moleculares anãs

    NASA Astrophysics Data System (ADS)

    Falceta-Gonçalves, D.; de Juli, M. C.; Jatenco-Pereira, V.

    2003-08-01

    Nuvens moleculares anãs se apresentam dinamicamente estáveis, embora possuam massas muito maiores que a massa de Jeans. Por este motivo, a estabilidade destes objetos não pode ser explicada considerando-se apenas a pressão térmica. Campos magnéticos, aproximadamente uniformes e de ~mG, exercem um termo extra de pressão que sustenta a nuvem, mas somente na direção perpendicular às linhas de campo. Para a direção paralela, ondas de Alfvén geradas por turbulências no meio, por exemplo, têm sido utilizadas. Estas, sendo supostamente fracamente amortecidas, poderiam sustentar a nuvem nesta direção. Entretanto, estes meios contêm grandes quantidades de poeira carregada eletricamente. Estes grãos de poeira possuem frequências cíclotron, que podem entrar em ressonância com as ondas. Neste trabalho calculamos os efeitos que o amortecimento cíclotron da poeira teriam na propagação da onda, e consequentemente na estabilidade da nuvem. Considerando um fluxo de ondas, com um dado espectro de frequências, e uma população de grãos de poeira, com distribuição de tamanho observada, foi possível mostrar que o amortecimento é eficiente em uma larga banda de frequências. Neste caso as ondas seriam rapidamente amortecidas gerando pequenas condensações de alta densidade, e não poderiam ser utilizadas para explicar a estabilidade de uma nuvem inteira. Desta forma, rotação e turbulência seriam candidatos alternativos para garantir a estabilidade destes objetos.

  10. Portugueses criam terapeuta virtual da fala

    E-print Network

    Instituto de Sistemas e Robotica

    avaliação de 30 terapeutas da fala, "numa escala de zero a cinco, teve a nota muito boa de 4,65", diz Fonseca, da Facul- dade de Medicina da Universidade de Lis- boa, ficou claro que uma ferramenta deste tipo

  11. Henrique da Rocha Lima*

    PubMed Central

    Bernardes Filho, Fred; Avelleira, João Carlos Regazzi

    2015-01-01

    Brazilian physician and researcher Henrique da Rocha Lima was born in 1879 in the city of Rio de Janeiro, where he studied medicine and obtained the degree of M.D. in 1901. He specialized in Clinical Medicine in Germany and was the ambassador in European countries of the scientific medicine that emerged from the Oswaldo Cruz Institute in the early twentieth century. Rocha Lima has discovered the causative agent of typhus and had a major contribution to the studies of yellow fever, Chagas disease, Carrión’s disease and histoplasmosis. His genius, his research and his discoveries projected his name, and, with it, the image of Brazil in the international scientific scene. PMID:26131867

  12. PRESIDNCIA DA REPBLICA CONTROLADORIA-GERAL DA UNIO

    E-print Network

    Maier, Rudolf Richard

    pessoal em exercício na Auditoria Interna, bem como da carência de pessoal qualificado para execução dessa trabalhos administrativos (secretária). Apesar dessa dificuldade, há que se registrar a boa qualidade do

  13. Leonardo da Vinci and the Downburst.

    NASA Astrophysics Data System (ADS)

    Gedzelman, Stanley David

    1990-05-01

    Evidence from the drawings, experiments, and writings of Leonardo da Vinci are presented to demonstrate that da Vinci recognized and, possibly, discovered the downburst and understood its associated airflow. Other early references to vortex flows resembling downbursts are mentioned.

  14. Lembranías da Companhia dramática Nacional

    E-print Network

    Calvet, Aldo

    1984-04-01

    Falecida, de Nelson Rodrigues; a Nilson Pena, de Melhor Cenógrafo e Figurinista de Canção dentro do Põ, de R. Magalhães Jr.; e a Anísio Medeiros, de Melhor Cenógrafo e Figurinista de A Raposa e as Uvas; todos em dinheiro da Prefeitura do Distrito Federal...

  15. AGUARDANDO HOMOLOGAO MINISTRIO DA EDUCAO

    E-print Network

    Maier, Rudolf Richard

    do Tratado da Amizade, Cooperação e Consulta entre a República #12;Federativa do Brasil e a República Portuguesa, Decreto 3.927, de 19 de setembro de 2001. A implementação deste Tratado por parte do governo

  16. Leonardo da EmileTruijen

    E-print Network

    Stevin Lect. room B Isaac Newton Lect. room C Daniel Bernoulli Lect. room D James Wa L.r.JCoenraad Stork L laboratories Departments Levels A Leonardo da Vinci - 6 gf B Isaac Newton - 6 gf C Daniel Bernoulli - 6 gf D

  17. Minerao de Sries Temporais por meio da Extrao de Caractersticas e da Identificao de Motifs

    E-print Network

    Batista, Gustavo

    Mineração de Séries Temporais por meio da Extração de Características e da Identificação de Motifs conhecimento de sé- ries temporais, por meio da extração de características e da identificação de motifs

  18. Normas de Emprstimo de Notebooks Da Finalidade

    E-print Network

    Paraná, Universidade Federal do

    Normas de Empréstimo de Notebooks Da Finalidade Art. 1 - Garantir aos estudantes vinculados ao Programa de Benefícios Econômicos da UFPR (Probem), acesso a notebook para fins acadêmicos, como ferramenta da devolução. #12;Art. 13 ­ Não é permitido: a) instalar e desinstalar qualquer programa do notebook

  19. Ministrio da Educao UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    confirmação da matrícula e solicitação de equivalências 10-12/fev - (TCC Lic e Bac ) Inscrição em monografia-21/nov (TCC Lic e Bac ) Prazo para entregar uma cópia da monografia para os membros da banca de avaliação Semana de Estudos 09-14/jun 01-06/dez (TCC Lic e Bac ) Semana de Apresentação de Monografias 09-14/jun 01

  20. The major histocompatibility complex genes impact pain response in DA and DA.1U rats.

    PubMed

    Guo, Yuan; Yao, Fan-Rong; Cao, Dong-Yuan; Li, Li; Wang, Hui-Sheng; Xie, Wen; Zhao, Yan

    2015-08-01

    Our recent studies have shown that the difference in basal pain sensitivity to mechanical and thermal stimulation between Dark-Agouti (DA) rats and a novel congenic DA.1U rats is major histocompatibility complex (MHC) genes dependent. In the present study, we further used DA and DA.1U rats to investigate the role of MHC genes in formalin-induced pain model by behavioral, electrophysiological and immunohistochemical methods. Behavioral results showed biphasic nociceptive behaviors increased significantly following the intraplantar injection of formalin in the hindpaw of DA and DA.1U rats. The main nociceptive behaviors were lifting and licking, especially in DA rats (P<0.001 and P<0.01). The composite pain scores (CPS) in DA rats were significantly higher than those in DA.1U rats in both phases of the formalin test (P<0.01). Electrophysiological results also showed the biphasic increase in discharge rates of C and A? fibers of L5 dorsal root in the two strains, and the net change of the discharge rate of DA rats was significantly higher than that of DA.1U rats (P<0.05). The mechanical thresholds decreased after formalin injection in both strains (P<0.01), and the net change in the mechanical threshold in DA was greater than that in DA.1U rats (P<0.05). The expression of RT1-B, representation of MHC class II molecule, in laminae I-II of L4/5 spinal cord in DA rats was significantly higher than that in DA.1U rats in the respective experimental group (P<0.05). These results suggested that both DA and DA.1U rats exhibited nociceptive responses in formalin-induced pain model and DA rats were more sensitive to noxious chemical stimulus than DA.1U rats, indicating that MHC genes might contribute to the difference in pain sensitivity. PMID:25861730

  1. PRESIDNCIA DA REPBLICA CONTROLADORIA-GERAL DA UNIO

    E-print Network

    Maier, Rudolf Richard

    INTERNA . Em cumprimento à Instrução Normativa SFC n.º 2, de 24/12/2002, o Gestor encaminhou, por meio do meio do Ofício n.º 253, de 31/3/2008, o Relatório Anual de Atividades da Auditoria Interna - RAINT Auditoria Interna PAINT/FUB para o exercício de 2008 foi enviado a esta CGU-PR, por meio do Ofício nº 1163

  2. SERVIO PBLICO FEDERAL MINISTRIO DA EDUCAO

    E-print Network

    Hanazaki, Natalia

    SERVIÇO PÚBLICO FEDERAL MINISTÉRIO DA EDUCAÇÃO UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE Psicossocial ­ Mestrado Profissional da Universidade Federal de Santa Catarina, atendendo ao disposto no item 2 atende ao item 3.8 do Edital) 9 20150004162 MARIANA VIDAL FOLTZ Homologada 10 20150003991 MAYARA MARIA

  3. SERVIO PBLICO FEDERAL MINISTRIO DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    SERVIÇO PÚBLICO FEDERAL MINISTÉRIO DA EDUCAÇÃO UNIVERSIDADE FEDERAL DE SANTA CATARINA PRÓ Docência (PIBID) da Universidade Federal de Santa Catarina, no uso de suas atribuições, torna público o Gabriela Nogueira de Souza 14102393 Classificada Ravi Sagae de Oliveira 15104819 Classificado Maria Paula

  4. Universidades nacionais a meio da tabela

    E-print Network

    Instituto de Sistemas e Robotica

    Universidades nacionais a meio da tabela no primeiro ranldng encomendado pela UE Ensino superior indicadores, as representantes por- tuguesas ficam a meio das tabelas do U-Multirank. Tanto a Católica como instituições nacionais acima do lugar 500 surgem mais uma vez a meio da tabela, entre a posição 388

  5. ANA TERESA FREITAS Fora da norma

    E-print Network

    Instituto de Sistemas e Robotica

    duas das áreas mais competitivas do momento: a biologia e a informática por sara sá m urante metade da biologia, em particular da genética, «onde nenhum projeto, hoje em dia, dispensa um especialista em, arregaçou as mangas e com outras duas sócias (Susa- na Santos, bióloga molecular, e Alexandra Fernandes

  6. Ministrio da Educao UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    Conhecimento: Literatura de Língua Francesa Processo: 23075.070275/2015-27 Número de vagas: 01 (uma) Número Doutorado em Letras e Tese em Literatura de Expressão Francesa / Teoria da Literatura Francesa, ou Literatura Comparada Francófona, obtidos na forma da lei. Tipos de Provas: Escrita (classificatória e

  7. Astronomy at School: Measurements of the Earth-Moon Distance. (Spanish Title: Astronomía en la Escuela: Medición de la Distancia Tierra-Luna.) Astronomia na Escola: Medida da Distância Terra-Lua

    NASA Astrophysics Data System (ADS)

    Paolantonio, Santiago; Pintado, Olga I.

    2006-12-01

    The aim of this project is to approach High School students to Science. We propose to measure the Earth-Moon distance using the parallax. The observation and measurements techniques and all the calculations needed are described in this paper. The results obtained in a test experience realized during 2003 are presented. This test shows that this is a feasible project and also shows which things needed to be improved. Se plantea la propuesta de un proyecto educativo dirigido al Nivel Medio de enseñanza, consistente en la determinación de la distancia Tierra - Luna por paralaje. Se describen las técnicas de observación, mediciones y cálculos. Se proporcionan a continuación los resultados obtenidos en la experiencia piloto realizada en el 2003, la que permitió comprobar la factibilidad de llevar a cabo la propuesta, así como perfeccionar los diferentes aspectos involucrados en la misma. Propomos neste trabalho um projeto educativo dirigido ao Ensino Médio que consiste na determinação da distância Terra-Lua pelo efeito da paralaxe. As técnicas de observação, medidas e cálculos auxiliares são descritos, e os resultados obtidos numa experiência-teste realizada no ano de 2003 apresentados. Este último teste permitiu comprovar a viabilidade de execução da proposta e aperfeiçoar diversos aspectos da mesma.

  8. Origin of the DA and non-DA white dwarf stars

    NASA Technical Reports Server (NTRS)

    Shipman, Harry L.

    1989-01-01

    Various proposals for the bifurcation of the white dwarf cooling sequence are reviewed. 'Primordial' theories, in which the basic bifurcation of the white dwarf sequence is rooted in events predating the white dwarf stage of stellar evolution, are discussed, along with the competing 'mixing' theories in which processes occurring during the white dwarf stage are responsible for the existence of DA or non-DA stars. A new proposal is suggested, representing a two-channel scenario. In the DA channel, some process reduces the hydrogen layer mass to the value of less than 10 to the -7th. The non-DA channel is similar to that in the primordial scenario. These considerations suggest that some mechanism operates in both channels to reduce the thickness of the outermost layer of the white dwarf. It is also noted that accretion from the interstellar medium has little to do with whether a particular white dwarf becomes a DA or a non-DA star.

  9. An Extension of PPLS-DA for Classification and Comparison to Ordinary PLS-DA

    PubMed Central

    Telaar, Anna; Liland, Kristian Hovde; Repsilber, Dirk; Nürnberg, Gerd

    2013-01-01

    Classification studies are widely applied, e.g. in biomedical research to classify objects/patients into predefined groups. The goal is to find a classification function/rule which assigns each object/patient to a unique group with the greatest possible accuracy (classification error). Especially in gene expression experiments often a lot of variables (genes) are measured for only few objects/patients. A suitable approach is the well-known method PLS-DA, which searches for a transformation to a lower dimensional space. Resulting new components are linear combinations of the original variables. An advancement of PLS-DA leads to PPLS-DA, introducing a so called ‘power parameter’, which is maximized towards the correlation between the components and the group-membership. We introduce an extension of PPLS-DA for optimizing this power parameter towards the final aim, namely towards a minimal classification error. We compare this new extension with the original PPLS-DA and also with the ordinary PLS-DA using simulated and experimental datasets. For the investigated data sets with weak linear dependency between features/variables, no improvement is shown for PPLS-DA and for the extensions compared to PLS-DA. A very weak linear dependency, a low proportion of differentially expressed genes for simulated data, does not lead to an improvement of PPLS-DA over PLS-DA, but our extension shows a lower prediction error. On the contrary, for the data set with strong between-feature collinearity and a low proportion of differentially expressed genes and a large total number of genes, the prediction error of PPLS-DA and the extensions is clearly lower than for PLS-DA. Moreover we compare these prediction results with results of support vector machines with linear kernel and linear discriminant analysis. PMID:23408965

  10. Ministrio da Educao UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    Ministério da Educação UNIVERSIDADE FEDERAL DO PARANÁ Pró-Reitoria de Gestão de Pessoas EDITAL N: Planejamento e Administração Escolar Área de Conhecimento: Organização do Trabalho Pedagógico Processo nº

  11. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Catarina, Centro de Ciências da Educação. Ata da1 nonagésima primeira reunião do Colegiado do Núcleo de, Giseli Day, Graziela Maria Beretta Lopez, Jodete Bayer6 Gomes Fullgraf, Márcia Regina Goulart da Silva

  12. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO;UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO INFANTIL-11-201128-11-201128-11-201128-11-2011ANTÔNIO MARIA MARÇAL TELO NUNES DA COSTAANTÔNIO MARIA MARÇAL TELO NUNES DA COSTAANTÔNIO MARIA MARÇAL TELO

  13. Analise Destendenciada das Flutuac~oes da Variabilidade da Frequ^encia Cardiaca: Melhorias e Aplicac~oes

    E-print Network

    Carvalho, João Luiz

    ´alise da variabilidade da frequ^encia card´iaca (HRV): permite detectar anormalidades no controle nervoso. Neste trabalho: Propomos melhorias no software que realiza a an´alise DFA da HRV (Figura 1) [3´alise destendenciada da HRV [3]. An´alise Destendenciada das Flutua¸c~oes 1) Obt´em-se o sinal de HRV (intervalos RR

  14. Da necessidade de princpios de Arquitetura da Informao para a Internet das Coisas

    E-print Network

    Floeter, Sergio Ricardo

    principles to the Internet of Things This article analyzes Internet of Things (IoT) scenario and its impacts Architecture; Internet of Things; Information ecosystems. Recebido em 09.03.2015 Aceito em 06.05.2015 1Da necessidade de princípios de Arquitetura da Informação para a Internet das Coisas Flavia Lacerda

  15. The Supernova Impostor SN 2010da

    NASA Astrophysics Data System (ADS)

    Binder, Breanna A.; Williams, Benjamin F.; Kong, Albert K. H.; Plucinsky, Paul P.; Gaetz, Terrance J.; Skillman, Evan D.; Dolphin, Andrew E.

    2016-01-01

    Supernova impostors are optical transients that, despite being assigned a supernova designation, do not signal the death of a massive star or accreting white dwarf. Instead, many impostors are thought to be major eruptions from luminous blue variables. Although the physical cause of these eruptions is still debated, tidal interactions from a binary companion has recently gained traction as a possible explanation for observations of some supernova impostors. In this talk, I will discuss the particularly interesting impostor SN 2010da, which exhibits high-luminosity, variable X-ray emission. The X-ray emission is consistent with accretion onto a neutron star, making SN 2010da a likely high mass X-ray binary in addition to a supernova impostor. SN 2010da is a unique laboratory for understanding both binary interactions as drivers of massive star eruptions and the evolutionary processes that create high mass X-ray binaries.

  16. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Professoras Sonia Maria Jordão de Castro e Regina Ingrid Bragagnolo 3. Assunto: Apresentação da Proposta de

  17. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO ADMINISTRATIVO S 1 - ISADORA BINOTTO GUIMARÃES GRUPO 4 ­ ESTUDANTES 1 ­ GABRIELA MARIA GOSSLER RODRIGUES DA SILVA

  18. "O financiamento da Cincia pretende garantir o

    E-print Network

    Instituto de Sistemas e Robotica

    acusado de estar a cortar no dinheiro para a Ciência. A secretária de Estado nega. Não houve mostra os valores que provam que o sistema tem recebido mais dinheiro. Porém, a secretária de Estado da Ciên- cia reconhece mudanças nos critérios de financiamento. Há menos dinheiro para bolsas e mais para

  19. The PAN-DA data acquisition system

    SciTech Connect

    Petravick, D.; Berg, D.; Berman, E.; Bernett, M.; Constanta-Fanourakis, P.; Dorries, T.; Haire, M.; Kaczar, K; MacKinnon, B.; Moore, C.; Nicinski, T.; Oleynik, G.; Pordes, R.; Sergey, G.; Votava, M.; White, V.

    1989-05-01

    The Online and Data Acquisition software groups at Fermi National Accelerator Laboratory have extended the VAXONLINE data acquisition package to include a VME based data path. The resulting environment, PAN-DA, provides a high throughput for logging, filtering, formatting and selecting events. 10 refs., 1 fig.

  20. The FINUDA experiment at DA?NE

    NASA Astrophysics Data System (ADS)

    Agnello, M.; Amaudruz, P. A.; Beer, G.; Benussi, L.; Bertani, M.; Bianco, S.; Botta, E.; Bressani, T.; Busso, I.; Calvo, D.; Camerini, P.; Celano, L.; Cerello, P.; D'Erasmo, G.; Fabbri, F. L.; Feliciello, A.; Filippi, A.; Filippini, V.; Fiore, E. M.; Fiore, L.; Gianotti, P.; Giardoni, M.; Gill, D. R.; Grion, N.; Guaraldo, C.; Headon, R.; Iazzi, F.; Lanaro, A.; Lee, L.; Lucherini, V.; Marcello, S.; Marciano, G.; Minetti, B.; Mirfakhrai, N.; Morra, O.; Nozdrin, A. A.; Olin, A.; Pantaleo, A.; Paticchio, V.; Raimondo, A.; Rossetto, E.; Rotondi, A.; Rui, R.; Salvini, P.; Sarwar, S.; Serdyuk, V.; Smith, G.; Venturelli, L.; Yen, S.; Zenoni, A.

    1997-02-01

    FINUDA is a large acceptance, high resolution magnetic spectrometer dedicated to hypernuclear physics. The experiment is in an advanced stage of construction and will run in 1997 at DA?NE, the Frascati o-Factory. Motivations, physics goals and expected performance are illustrated.

  1. The Finuda Experiment at DA?NE

    NASA Astrophysics Data System (ADS)

    Bressani, T.; Bergo, D.; Botta, E.; Busso, L.; Calvo, D.; Cerello, P.; Feliciello, A.; Filippi, A.; Marcello, S.; Morra, O.; Panzarasa, A.; Raimondo, A.; Agnello, M.; Iazzi, F.; Minetti, B.; Celano, L.; D'Erasmo, G.; Fiore, E. M.; Fiore, L.; Pantaleo, A.; Paticchio, V.; Tagliente, G.; Bianconi, A.; Bonomi, G.; Venturelli, L.; Zenoni, A.; Benussi, L.; Bertani, M.; Bianco, S.; Fabbri, F. L.; Gianotti, P.; Giardoni, M.; Lucherini, V.; Pace, E.; Pallotta, M.; Sarwar, S.; Serdyuk, V.; Trasatti, L.; Filippini, V.; Marchesotti, M.; Marciano, G.; Rotondi, A.; Mirfakhrai, N.; Bottan, P.; Camerini, P.; Grion, N.; Rui, R.; Wheadon, R.; Amaudruz, P.; Beer, G.; Olin, A.

    2000-09-01

    The FINUDA experiment at DA?NE, the recently commissioned Frascati ?-Factory, is now ready to start the data taking. Main expected performances of the detector are reviewed. The initial physics program, aiming to study the spectroscopy and the decay of Hypernuclei formed following K- capture at rest, is described. Further developement of the detector capabilities are outlined.

  2. How to Think Like Leonardo da Vinci

    ERIC Educational Resources Information Center

    Caouette, Ralph

    2008-01-01

    To be effective and relevant in twenty-first-century learning, art needs to be more inclusive. In this article, the author discusses how teachers can find a good example in Leonardo da Vinci for building an art program. His art, design, and curiosity are the perfect foundation for any art program, at any level. (Contains 3 resources and 3 online…

  3. Dilma Vana Rousseff Presidenta da Repblica

    E-print Network

    Maier, Rudolf Richard

    Toledo Camargo Vice-Reitora: Profª. Sônia Nair Báo Decano de Ensino de Graduação: Prof. Mauro Luiz Rabelo Universitário Darcy Ribeiro ­ Asa Norte Prédio da Reitoria, bloco B, 1º andar CEP: 70910-900 Brasília-DF, Brasil Projeto Gráfico, Editoração Eletrônica e Capa: Mauro Pereira Bento #12;Relatório de Gestão 2012 Gestores

  4. Ministrio da Educao Secretaria de Educao Superior

    E-print Network

    Maier, Rudolf Richard

    Toledo Camargo Vice-Reitora: Profª. Sônia Nair Báo Decano de Ensino de Graduação: Prof. Mauro Luiz Rabelo ­ Asa Norte Prédio da Reitoria, Bloco B, 1º andar CEP: 70910-900 Brasília-DF, Brasil Telefones: (61 Alves de Faria Decanato de Ensino de Graduação DEG Prof. Mauro Luiz Rabelo Decanato de Pesquisa e Pós

  5. Ministrio da Educao Secretaria de Educao Superior

    E-print Network

    Maier, Rudolf Richard

    Superior UNIVERSIDADE DE BRASÍLIA Reitor: Prof. Ivan Marques de Toledo Camargo Vice-Reitora: Profª. Sônia Nair Báo Decano de Ensino de Graduação: Prof. Mauro Luiz Rabelo Decano de Pesquisa e Pós Universitário Darcy Ribeiro ­ Asa Norte Prédio da Reitoria, Bloco B, 1º andar CEP: 70910-900 Brasília-DF, Brasil

  6. Jeronimo Gomes Da Silva Neto Curriculum Vitae

    E-print Network

    Hopkins, William A.

    , U.S. Fish and Wildlife Service Back Bay National Wildlife Refuge, VA. May 2013 ­ September 2013 LeadJeronimo Gomes Da Silva Neto Curriculum Vitae Hellbender Field Technician Wildlife Ecotoxicology and Physiology Ecology Program Department of Fish and Wildlife Conservation, Virginia Tech, VA EDUCATION Virginia

  7. Estudo da Influncia de Seqncias Polipeptdicas e

    E-print Network

    Neshich, Goran

    no ASTRAL SCOP Genetic Domain Sequence (Brenner et al., 2000) que é derivada da base de dados PDB SEQRES. Foram então escolhidos três bancos de dados com diferentes níveis de similaridade: ASTRAL SCOP 10, ASTRAL SCOP 40 e ASTRAL SCOP 70, com valores máximos de 10

  8. Ministrio da Educao UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    Departamento de Linguística, Letras Clássicas e Vernáculas Área de Conhecimento: Literatura Brasileira Matéria Específica: Literatura Brasileira e Teoria da Literatura Processo: 23075.115067/2011-31 Número de Vagas: 01

  9. Ministrio da Educao Universidade Federal do Paran

    E-print Network

    Paraná, Universidade Federal do

    (Depto/Setor) Departamento de Biologia Celular - Setor Ciências Biológicas Área temática do Programa desenvolvidas As atividades internas serão realizadas no Depto de Biologia Celular - BL da UFPR e as atividades Departamento de Biologia Celular E-mail: marmend@ufpr.br (preferencialmente) Seleção Data: 05/06/2013 Local

  10. Maria Adelaide Amaral ou a Crise da Classe Média Brasileira

    E-print Network

    Ravetti, Graciela; Rojo, Sara

    1996-10-01

    Adelaide Amaral ou a Crise da Classe Média Brasileira Graciela Ravetti e Sara Rojo INTRODUÇÃO l. A família Quando entramos em contato com a produção dramática da escritora brasileira Maria Adelaide Amaral, mergulhamos no mundo privado da classe média... limite do privado, romper com a imagem do amor cor de rosa ou dos anúncios publicitários que se valem da família feliz para vender carros. A obra entra nas lutas internas do poder, nas pequenas ou grandes maldades, nas pessoas asfixiadas pela repressão...

  11. A Day in the Life at DaVita Academy

    ERIC Educational Resources Information Center

    Weinstein, Margery

    2010-01-01

    When a company name means "giving life," the bar for learning and development programs is held high. In this article, the author describes what it takes to graduate from DaVita Academy, the soft skills training program dialysis services company DaVita offers all its employees. DaVita's chief executive officer, Kent Thiry, states that the Academy…

  12. ciclo di conferenze organizzato da Politecnico di Milano,

    E-print Network

    'Informazione, Corso di laurea in Ingegneria delle Telecomunicazioni, Liceo Scientifico Statale Leonardo da Vinci al di'Informazione Politecnico di Milano 02.2399.9714 quintafacolta@polimi.it Liceo Scientifico Statale Leonardo da Vinci Centro dello spazio, al di là del tempo Liceo Scientifico Statale Leonardo da Vinci Centro Congressi

  13. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Catarina, Centro de Ciências da Educação. Ata da1 nonagésima quinta reunião, do Colegiado do Núcleo de Maria8 Beretta Lopez, Jodete Bayer Gomes Fülgraff, Josiana Piccoli, Juliane Mendes Rosa La9 Banca

  14. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 sétima reunião Sônia5 Maria Jordão de Castro; as professoras efetivas: Carolina Shimomura Spinelli, Débora6 Cristina de

  15. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Catarina, Centro de Ciências da Educação. Ata da1 octogésima nona reunião do Colegiado do Núcleo de Maria Beretta Lopez, Sonia Mary Valente8 Bayestorff, Caroline Machado Momm, Regina Ingrid Bragagnolo

  16. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Funcional Horizontal da Profª Sonia Maria Jordão de Castro classe DIV para classe DIV nível 1. Relatora da Profª Sonia Maria Jordão de Castro classe DIV nível 1 para classe DIV nível 2. Relatora: Profª

  17. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 oitava reunião Sônia Maria5 Jordão de Castro; as professoras efetivas: Carolina Shimomura Spinelli, Débora Cristina de6

  18. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Catarina, Centro de Ciências da Educação. Ata da1 nonagésima segunda reunião do Colegiado do Núcleo de, Giseli Day, Giandréa Reuss Strenzel, Graziela Maria6 Beretta Lopez, Jodete Bayer Gomes Fullgraf, Josiana

  19. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 décima reunião do e de5 Pesquisa: Sônia Maria Jordão de Castro; as Professoras Efetivas: Caroline Machado6 Momm

  20. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Hanazaki, Natalia

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO COLÉGIO DE APLICAÇÃO Educação da Universidade Federal de Santa Catarina, no uso de suas atribuições e, tendo em vista o que ­ Maria Eduarda Marinho de Souza inscrição 201 ­ nascimento 06/01/2000 7 ­ Amanda Juliana Schutz da Costa

  1. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 quarta reunião Sônia5 Maria Jordão de Castro; as professoras efetivas: Caroline Machado Momm, Carolina6 Shimomura

  2. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Catarina, Centro de Ciências da Educação. Ata da1 nonagésima reunião do Colegiado do Núcleo de Gomes Fulgraff, Sônia Maria Jordão de Castro, Giandrea7 Reuss Strenzel, Graziela Maria Beretta Lopez

  3. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Catarina, Centro de Ciências da Educação. Ata da1 octogésima nona (B) reunião do Colegiado do Núcleo de Maria Beretta Lopez, Rose Elaine Waltrick,7 Caroline Machado Momm, Regina Ingrid Bragagnolo, Soraya

  4. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Catarina, Centro de Ciências da Educação. Ata da1 nonagésima terceira reunião do Colegiado do Núcleo de Cristina de Sampaio Peixe, Eloisa Raquel de6 Oliveira, Giseli Day, Giandréa Reuss Strenzel, Graziela Maria

  5. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 décima quarta reunião; a Coordenadora5 Pedagógica e de Pesquisa: Sônia Maria Jordão de Castro; as Professoras Efetivas: Caroline6

  6. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Graziela Maria Beretta López 4. Assunto: Estágio Probatório (2º sem.) da Profª Regina Ingrid Bragagnolo Relatora: Profª Sonia Maria Jordão Castro 5. Assunto: Estágio Probatório (2º sem.) da Profª Débora Cristina

  7. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 décima terceira; a Coordenadora5 Pedagógica e de Pesquisa: Sônia Maria Jordão de Castro; as Professoras Efetivas: Caroline6

  8. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 nona reunião do; a Coordenadora5 Pedagógica e de Pesquisa: Sônia Maria Jordão de Castro; as Professoras Efetivas: Carolina6

  9. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Catarina, Centro de Ciências da Educação. Ata da1 nonagésima quarta sessão, extraordinária, do Colegiado do, Giandréa Reuss Strenzel,8 Graziela Maria Beretta López, Jodete Bayer Gommes Fullgraf, Josiana Piccolli

  10. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 décima primeira Waltrick; a Coordenadora5 Pedagógica e de Pesquisa: Sônia Maria Jordão de Castro; as Professoras Efetivas

  11. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Universidade Federal de Santa Catarina, Centro de Ciências da Educação. Ata da centésima1 décima segunda; a Coordenadora5 Pedagógica e de Pesquisa: Sônia Maria Jordão de Castro; as Professoras Efetivas: Caroline6

  12. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO profª Sonia Maria Jordão de Castro da Classe D3 Nível 3 para Classe D3 Nível 4. Relatora: presidente da comissão Profª Graziela Maria Beretta López 5. Apreciação e aprovação do processo de progressão funcional

  13. Universidade Federal de Santa Catarina Centro de Cincias da Sade

    E-print Network

    Hanazaki, Natalia

    dezembro de 2012, às 08h30min, na sala de aula da UTI- Hospital Universitário - HU. 2.3-Data da seleção: 13 de dezembro de 2012, às 08h00min, na sala de aula da UTI- Hospital Universitário - HU. O Resultado do

  14. Universidade Federal de Santa Catarina Centro de Cincias da Sade

    E-print Network

    Hanazaki, Natalia

    : 6 de dezembro de 2012, às 08h30min, na sala de aula da UTI- Hospital Universitário - HU. Leia-se: 2.3-Data da seleção: 13 de dezembro de 2012, às 08h00min, na sala de aula da UTI- Hospital Universitário

  15. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA SADE

    E-print Network

    Hanazaki, Natalia

    aula da UTI- Hospital Universitário - HU Leia-se: 2.3-Data da seleção: 15 e 16 de dezembro de 2014, às 08h00min, na sala de aula da UTI- Hospital Universitário ­ HU. OBS.: A definição de data que cada

  16. The Moon Phases in a Paper Box. (Spanish Title: Las Fases de la Luna en Una Caja de Cartón.) As Fases da Lua Numa Caixa de Papelão

    NASA Astrophysics Data System (ADS)

    de Fátima O. Saraiva, Maria; Amador, Cláudio B.; Kemper, Érico; Goulart, Paulo; Muller, Angela

    2007-12-01

    We present a very simple concrete model to demonstrate the concept of phases of an illuminated body. The main objective of our model is to help the understanding of the Moon phases as viewed from the perspective of an observer on Earth. The material allows the visualization of two important effects: (1st) even though all the time half Moon is illuminated by the Sun, we see different fractions of the illuminated Moon surface, depending on our angle of sight; (2nd) the orientation of the convex part of the Moon in the crescent and waning phases on the sky also depends on our perspective from Earth. The use of a closed box allows one to see the contrast among the different phases with no need of a dark room. We also present a text on the Moon phases, emphasizing the dependence of the aspect of the bright part on the angle of sight. En este trabajo proponemos la construcción de material didáctico de bajo costo para demostración del concepto de fases de un cuerpo iluminado. El principal objetivo de nuestro material es facilitar la comprensión de las fases de la Luna desde la perspectiva de un observador en la Tierra. El material ayuda la visualización de dos efectos importantes: (1º) a pesar de tener siempre la mitad de la Luna (representada por una bolita de espuma plástica o de ping-pong), iluminada por el Sol ( representado por una fuente de luz natural o artificial), vemos diferentes fracciones de su superficie iluminada, dependiendo del ángulo por el cual la vemos; (2º) la orientación del borde convexo de la Luna en las fases Creciente y Menguante también depende de la perspectiva por la cual la miramos desde la Tierra. El uso de una caja cerrada permite observar el contraste entre las diferentes fases sin necesidad de estar en un recinto oscuro. Presentamos también un texto explicativo sobre las fases de la Luna, enfatizando la dependencia de la apariencia de la parte iluminada con el ángulo de visión. Neste trabalho propomos a construção de material didático de baixo custo para demonstração do conceito de fases de um corpo iluminado. O principal objetivo de nosso material é facilitar a compreensão das fases da Lua da perspectiva de um observador na Terra. O material ajuda na visualização de dois efeitos importantes: (1º) mesmo tendo sempre a metade da "Lua" (representada por uma bolinha de isopor ou de ping-pong) iluminada pelo "Sol" (representado por uma fonte de luz natural ou artificial), nós vemos diferentes frações de sua superfície iluminada, dependendo do ângulo pelo qual a olhamos; (2º) a orientação da borda convexa da Lua nas fases Crescente e Minguante também depende da perspectiva pela qual a olhamos da Terra. O uso de uma caixa fechada permite observar o contraste entre as diferentes fases sem necessidade de estar em uma sala escurecida. Apresentamos também um texto explicativo sobre fases da Lua, enfatizando a dependência da aparência da parte iluminada com o ângulo de visada.

  17. Homogeneous generation of iDA neurons with high similarity to bona fide DA neurons using a drug inducible system.

    PubMed

    Park, Hanseul; Kim, Hongwon; Yoo, Junsang; Lee, Jaekwang; Choi, Hwan; Baek, Soonbong; Lee, C Justin; Kim, Janghwan; Lengner, Christopher J; Sung, Jung-Suk; Kim, Jongpil

    2015-12-01

    Recent work generating induced dopaminergic (iDA) neurons using direct lineage reprogramming potentially provides a novel platform for the study and treatment Parkinson's disease (PD). However, one of the most important issues for iDA-based applications is the degree to which iDA neurons resemble the molecular and functional properties of their endogenous DA neuron counterparts. Here we report that the homogeneity of the reprogramming gene expression system is critical for the generation of iDA neuron cultures that are highly similar to endogenous DA neurons. We employed an inducible system that carries iDA-inducing factors as defined transgenes for direct lineage reprogramming to iDA neurons. This system circumvents the need for viral transduction, enabling a more efficient and reproducible reprogramming process for the generation of genetically homogenous iDA neurons. We showed that this inducible system generates iDA neurons with high similarity to their bona fide in vivo counterparts in comparison to direct infection methods. Thus, our results suggest that homogenous expression of exogenous genes in direct lineage reprogramming is critical for the generation of high quality iDA neuron cultures, making such culture systems a valuable resource for iDA-based drug screening and, ultimately, potential therapeutic intervention in PD. PMID:26370928

  18. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    Programas e Projetos de Extensão 2015. A Universidade Federal do Paraná (UFPR), por meio da Pró-Reitoria de para produção de biodiesel metílico, uma integração universidade, escola, comunidade e meio 3 Colheita meio ambiente 2 Direito e Cidadania: a luta pela moradia 3 Divulgando a informação técnica e

  19. Ministrio da Educao UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    Departamento de Linguística, Letras Clássicas e Vernáculas Área de Conhecimento: Teoria Literária e Literatura Brasileira Matéria Específica: Teoria da Literatura; Literatura Brasileiras I, II, III e IV; Leitura e literatura na escola Processo: 23075. 046186/2013-06 Número de Vagas: 01 (uma) N.º DE ORDEM NOME M�DIA 01

  20. A Influência da Escola e da Mídia na Obtenção dos Conhecimentos Astronômicos

    NASA Astrophysics Data System (ADS)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2006-08-01

    O universo em que vivemos possui segredos jamais imaginados pelo homem, fruto da pequena proporção que ocupamos diante de um cosmos infinito. A astronomia funciona como um instrumento que sacia a sede humana em desvendar esses segredos, estudando as galáxias, quasares, pulsares além da existência de todos os elementos que preenchem o espaço cósmico, o vácuo, não mais vazio como se pensou em outros tempos. A mídia explora esse campo de forma mística e também científica. A difusão adequada e dentro dos padrões educacionais vigentes, de conceitos astronômicos, se faz necessária, devido sua presença nos conteúdos escolares, centros de ciência e na mídia, de modo geral. A reforma do Currículo Básico da Escola Pública da maioria dos Estados brasileiros introduziu conceitos astronômicos desde a pré-escola até o Ensino Médio. Num estudo realizado com 1.032 alunos do Ensino Médio de seis escolas estaduais, revelou-se através da aplicação de um questionário que abordava conheciment os básicos em astronomia, como estes foram adquiridos e qual era a infra-estrutura oferecida pela escola: para 66,2% dos entrevistados o professor já fez alguma apresentação a respeito de astronomia. O presente estudo revelou também que 44,5% dos alunos entrevistados adquiriram seus conhecimentos astronômicos na escola, 28,1% através da televisão e 27,4% afirmaram que seus conhecimentos foram obtidos através de outros tipos de mídia (internet, filmes e revistas). Embora o estudo revele claramente que há certo equilíbrio na forma em que os alunos obtiveram seus conhecimentos astronômicos, a mídia ainda explora e muitas vezes desperta o interesse pela astronomia com assuntos que não fazem parte de nosso cotidiano como, por exemplo, o homem na Lua, os projetos espaciais e a primeira viagem de um astronauta brasileiro no espaço. Porém, em certos casos, a mídia pode promover conhecimentos incompletos ou mesmo equivocados sobre os conceitos que envolvam a astronomia, como por exemplo a propagação do som no vácuo observado na maioria dos filmes de f icção científica ou da existência das estações do ano em função da distância da Terra ao Sol, em conformidade com o questionário aplicado.

  1. Qual o Papel da Escola e da Mídia na Obtenção dos Conhecimentos Astronômicos?

    NASA Astrophysics Data System (ADS)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2007-08-01

    É amplamente reconhecido que as pessoas em geral têm grande fascínio e interesse pela Astronomia. Por outro lado, o conteúdo dessa área incluído no ensino formal está longe de ser abrangente e suficiente para suprir a demanda. Esse interesse permite aperfeiçoar a divulgação e o ensino não formal de Astronomia através da mídia aliando a adequação do conteúdo à expectativa das pessoas. A reforma do Currículo Básico da Escola Pública da maioria dos Estados brasileiros tem introduzido Astronomia desde a pré-escola até o Ensino Médio. Num estudo realizado com 1180 alunos do Ensino Médio de seis escolas estaduais, revelou-se através da aplicação de um formulário contendo questões que abordavam conhecimentos básicos em Astronomia, como foram adquiridos tais conhecimentos e à infra-estrutura da escola. Para 66,1% dos entrevistados o professor já fez alguma apresentação a respeito de Astronomia. O presente estudo revelou também que 54,4% dos alunos entrevistados adquiriram seus conhecimentos astronômicos na escola, 18,4% através da televisão e 27,1% afirmaram que seus conhecimentos foram obtidos através de outros tipos de mídia (internet, livros didáticos, filmes e revistas). Embora o estudo revele claramente que há certo equilíbrio no meio em que os alunos obtiveram seus conhecimentos astronômicos, a mídia busca não somente sua difusão, mas a disponibilização desse conhecimento de maneira correta, que às vezes, não é atingido, apresentando conceitos sem fundamentação e incorretos. Por outro lado, no dia-a-dia escolar, é comum encontrar professores que vêm para as aulas com concepções prévias, que podem diferir substancialmente das idéias a serem ensinadas, dificultando o aprendizado de futuros conceitos científicos. Uma avaliação criteriosa, avaliando as dificuldades dos professores em determinar o sentido correto dos conceitos e observando a metodologia que utilizam no ensino, poderá proporcionar uma melhor compreensão sobre as concepções alternativas, presentes no ensino de Astronomia.

  2. Rational design of D-A1-D-A2 conjugated polymers with superior spectral coverage.

    PubMed

    Hedström, Svante; Tao, Qiang; Wang, Ergang; Persson, Petter

    2015-10-28

    The spectral coverage of a light-harvesting polymer largely determines the maximum achievable photocurrent in organic photovoltaics, and therefore constitutes a crucial parameter for improving their performance. The D-A1-D-A2 copolymer motif is a new and promising design strategy for extending the absorption range by incorporating two acceptor units with complementary photoresponses. The fundamental factors that promote an extended absorption are here determined for three prototype D-A1-D-A2 systems through a combination of experimental and computational methods. Systematic quantum chemical calculations are then used to reveal the intrinsic optical properties of ten further D-A1-D-A2 polymer candidates. These investigated polymers are all predicted to exhibit intense primary absorption peaks at 615-954 nm, corresponding to charge-transfer (CT) transitions to the stronger acceptor, as well as secondary absorption features at 444-647 nm that originate from CT transitions to the weaker acceptors. Realization of D-A1-D-A2 polymers with superior spectral coverage is thereby found to depend critically on the spatial and energetic separation between the two distinct acceptor LUMOs. Two promising D-A1-D-A2 copolymer candidates were finally selected for further theoretical and experimental study, and demonstrate superior light-harvesting properties in terms of significantly extended spectral coverage. This demonstrates great potential for enhanced light-harvesting in D-A1-D-A2 polymers via multiple absorption features compared to traditional D-A polymers. PMID:26394002

  3. Que pensa você da arte de esquerda?

    E-print Network

    Boal, Augusto

    1970-04-01

    demiurgo da arte—este lugar comum já foi destruído por Roberto Schwarz {Teoria e Prática, No. 2) onde observa que entre o artista e o consumidor, numa sociedade capitalista, insere-se o mediador-capital, o mediado-patrocinador. O dinheiro, este sim, é o... para o povo e justamente por isso todos os governos excluem, cuidadosamente, a verdadeira popularização do teatro dos seus planos de auxílio. Em geral, dá-se dinheiro para que os preços caiam de sete para três cruzeiros—as chamadas temporadas...

  4. The Digital Restoration of Da Vinci's Sketches

    E-print Network

    Sparavigna, Amelia

    2009-01-01

    A sketch, found in one of Leonardo da Vinci's notebooks and covered by the written notes of this genius, has been recently restored. The restoration reveals a possible self-portrait of the artist, drawn when he was young. Here, we discuss the discovery of this self-portrait and the procedure used for restoration. Actually, this is a restoration performed on the digital image of the sketch, a procedure that can easily extended and applied to ancient documents for studies of art and palaeography.

  5. DA?NE and KLOE-2

    NASA Astrophysics Data System (ADS)

    De Santis, Antonio

    2015-11-01

    The DA?NE collider, located in the Frascati National Laboratories of INFN, has two main rings, where electrons and positrons are stored to collide at a center of mass energy of 1.02 GeV, the ? resonance mass. The KLOE-2 experiment is located at the collider interaction region (IR). The detector is capable of observing and collecting data coming from ? decay: charged and neutral kaon pairs, lighter unflavored mesons (?, ? \\prime , f0, ao, ? /? ). In the first half of 2013 the KLOE detector has been upgraded inserting new detector layers in the inner part of the apparatus, around the IR in order to improve detector hermeticity and acceptance. The long shutdown has been used to undertake a general consolidation program aimed at improving the DA?NE performances. This contribution presents the ?-factory setup and the achieved performances in terms of beam currents, luminosity and related aspects together with the KLOE-2 physics program, upgrade status report and recent physics results.

  6. DAEdALUS and Dark Matter

    E-print Network

    Kahn, Yonatan; Thaler, Jesse; Toups, Matthew

    2014-01-01

    Among laboratory probes of dark matter, fixed-target neutrino experiments are particularly well-suited to search for light weakly-coupled dark sectors. In this paper, we show that the DAEdALUS source setup---an 800 MeV proton beam impinging on a target of graphite and copper---can improve the present LSND bound on dark photon models by an order of magnitude over much of the accessible parameter space for light dark matter when paired with a suitable neutrino detector such as LENA. Interestingly, both DAEdALUS and LSND are sensitive to dark matter produced from off-shell dark photons. We show for the first time that LSND can be competitive with searches for visible dark photon decays, and that fixed-target experiments have sensitivity to a much larger range of heavy dark photon masses than previously thought. We review the mechanism for dark matter production and detection through a dark photon mediator, discuss the beam-off and beam-on backgrounds, and present the sensitivity in dark photon kinetic mixing for...

  7. The Case: Bunche-Da Vinci Learning Partnership Academy

    ERIC Educational Resources Information Center

    Eisenberg, Nicole; Winters, Lynn; Alkin, Marvin C.

    2005-01-01

    The Bunche-Da Vinci case described in this article presents a situation at Bunche Elementary School that four theorists were asked to address in their evaluation designs (see EJ791771, EJ719772, EJ791773, and EJ792694). The Bunche-Da Vinci Learning Partnership Academy, an elementary school located between an urban port city and a historically…

  8. 40 CFR 60.48Da - Compliance provisions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Csg ). The continuous flow monitoring system specified in § 60.49Da...If the option to use the flow monitoring system in § 60.49Da(m) is selected...recording data from the continuous flow monitoring system specified in §...

  9. 40 CFR 60.48Da - Compliance provisions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Csg ). The continuous flow monitoring system specified in § 60.49Da...If the option to use the flow monitoring system in § 60.49Da(m) is selected...recording data from the continuous flow monitoring system specified in §...

  10. 40 CFR 60.48Da - Compliance provisions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Csg ). The continuous flow monitoring system specified in § 60.49Da...If the option to use the flow monitoring system in § 60.49Da(m) is selected...recording data from the continuous flow monitoring system specified in §...

  11. Universidade Federal de Santa Catarina Centro de Cincias da Educao

    E-print Network

    Floeter, Sergio Ricardo

    Universidade Federal de Santa Catarina Centro de Ciências da Educação Núcleo de Desenvolvimento-Graduação Joana Maria Pedro Pró-Reitor de Pesquisa Jamil Assreuy Pró-Reitor de Extensão Edison da Rosa Pró. Stemmer e Sonia Maria Jordão de Castro Coordenadora de Saúde/NDI Elfy Margrit Göhring Weiss #12;RELATÓRIO

  12. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO ao 2º ano de exercício) da Profª Josiana Picolli. Relatora: Profª Graziela Maria Beretta López 6 Regina Ingrid Bragagnolo Relatora: Profª Sonia Maria Jordão de Castro 7. Assunto: Processo de Estágio

  13. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO de 2014 REALIZAÇÃO MEC MINISTÉRIO DA EDUCAÇÃO UFSC UNIVERSIDADE FEDERAL DE SANTA CATARINA CED CENTRO/NDI/CED/UFSC Drª VERENA WIGGERS COORDENADORA ADJUNTA ­ POLO ARARANGUÁ ­ CEDEI/NDI/CED/UFSC Msc. MARIA RAQUEL

  14. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO professora Jane Cunha Pacheco. Relatora: professora Sonia Maria Jordão de Castro 6. Assunto: Progressão: professora Sonia Maria Jordão de Castro 7. Assunto: Progressão Funcional Vertical da Classe D nível 4 para

  15. MINISTRIO DA EDUCAO UNIVERSIDADE FEDERAL DO RIO DE JANEIRO

    E-print Network

    Liu, I-Shih

    inteiramente gratuito do programa na Instituição. Nos termos do Regimento e das Normas Acadêmicas: a proposta e Regimento do PROFHISTÓRIA. b) Documento de aprovação institucional do curso¸ ou declaração participação da Instituição no PROFHISTÓRIA estará condicionada à aprovação institucional do curso antes da

  16. Berengario da Carpi: a pioneer in neurotraumatology.

    PubMed

    Di Ieva, Antonio; Gaetani, Paolo; Matula, Christian; Sherif, Camillo; Skopec, Manfred; Tschabitscher, Manfred

    2011-05-01

    Berengario da Carpi was one of the most famous physicians of the 16th century, a recognized master of anatomy and surgery, an emblematic "Renaissance man" who combined his medical experience and engineering knowledge to design new surgical instruments, and effectively used the arts of writing and drawing to describe state-of-the-art medicine and provide illustrations of anatomical structures. His greatest contribution to medicine was to write the most important work on craniocerebral surgery of the 16th century, the Tractatus de Fractura Calvae sive Cranei (Treatise on Fractures of the Calvaria or Cranium), in which he described an entire set of surgical instruments to be used for cranial operations to treat head traumas that became a reference for later generations of physicians. This was a systematic treatise covering the mechanisms, classification, and medical and surgical treatment of head traumas, and can be considered a milestone in the history of neurotraumatology. PMID:21128734

  17. 75 FR 52292 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40 and DA 40F Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40...airworthiness directive (AD) for all Diamond Aircraft Industries GmbH Models DA 40...identified in this proposed AD, contact Diamond Aircraft Industries GmbH, N.A....

  18. 75 FR 52292 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40 and DA 40F Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    ... ``significant rule'' under the DOT Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); and 3... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Diamond Aircraft... new airworthiness directive (AD) for all Diamond Aircraft Industries GmbH Models DA 40 and DA...

  19. ATA N. 99 / COLEGIADO / 2011 Universidade Federal de Santa Catarina, Centro de Cincias da Educao. Ata da nonagsima1

    E-print Network

    Floeter, Sergio Ricardo

    ATA N. 99 / COLEGIADO / 2011 Universidade Federal de Santa Catarina, Centro de Ciências da Educação, Giseli Day, Graziela Maria Beretta Lopez, Jane Cunha Pacheco6 Derner, Jodete Bayer Gommes Fullgraf Costa. Justificaram ausência: as professoras Márcia Regina Goulart da Silva Stemmer, Sônia12 Maria

  20. ATA N. 100 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Cincias da Educao. Ata da centsima1

    E-print Network

    Floeter, Sergio Ricardo

    ATA N. 100 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Ciências da Regina Goulart da Silva Stemmer e Sônia Maria Jordão de Castro; a coordenadora de Saúde: Elfy5 Margrit Reuss Strenzel, Giseli Day, Graziela Maria Beretta Lopez, Josiana7 Piccolli, Juliane Mendes Rosa La

  1. ATA N. 101 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Cincias da Educao. Ata da centsima1

    E-print Network

    Floeter, Sergio Ricardo

    ATA N. 101 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Ciências da; as4 coordenadoras pedagógicas Sonia Maria Jordão de Castro e Marcia Regina Goulart da Silva5 Stemmer Momm, Graziela12 Maria Beretta López, Pricilla Cristine Trierweiller, Ligia Mara Santos, Sandra Maria

  2. Respostas religiosas à aids no Brasil: impressões de pesquisa acerca da Pastoral de DST/Aids da Igreja Católica1

    PubMed Central

    Seffner, Fernando; Silva, Cristiane Gonçalves Meireles da; Maksud, Ívia; Garcia, Jonathan; Rios, Luís Felipe; Natividade, Marcelo; Borges, Priscila Rodrigues; Parker, Richard; Terto, Veriano

    2009-01-01

    O texto encontra-se estruturado em quatro partes. Na primeira delas, apresentamos um conjunto de considerações e informações acerca da situação da aids no Brasil, das relações entre religião, sexualidade, aids e estado laico, bem como uma descrição mais clara do Projeto Respostas Religiosas ao HIV/Aids no Brasil, do qual este texto apresenta algumas impressões de pesquisa preliminares. A seguir, dedicamos um item a apresentação da Pastoral de DST/Aids, sua história, estrutura e objetivos. No item seguinte problematizamos diversas questões em particular no âmbito das relações Estado e Igreja, relações entre agentes de pastoral e hierarquia da Igreja, e questões ligadas mais diretamente à sexualidade e aids, todas referenciadas ao trabalho da Pastoral de DST/Aids. Ao final, apresentamos a bibliografia e fontes consultadas. PMID:20442806

  3. Outubro/2015 Reunio da PROPG/UFSC com os

    E-print Network

    Hanazaki, Natalia

    Mestrado Profissional em Ensino de Física ­ Polo de Blumenau/SC (em apreciação) #12;4. Prêmio CAPES de Teses 2015 Autor: Marco Antônio de Oliveira Vieira Goulart Orientador: Prof. Newton Carneiro Affonso da

  4. Hypernuclear Physics with stopped K? at DA Phi NE

    NASA Astrophysics Data System (ADS)

    Agnello, M.; Amaudruz, P. A.; Beer, G.; Benussi, L.; Bertani, M.; Bianco, S.; Botta, E.; Bressani, T.; Busso, L.; Calvo, D.; Camerini, P.; Celano, L.; Cerello, P.; D'Erasmo, G.; Fabbri, F. L.; Feliciello, A.; Filippi, A.; Filippini, V.; Fiore, E. M.; Fiore, L.; Gianotti, P.; Giardoni, M.; Gill, D. R.; Grion, N.; Guaraldo, C.; Iazzi, F.; Lanaro, A.; Lee, L.; Lucherini, V.; Marcello, S.; Marciano, G.; Minetti, B.; Mirfakhrai, N.; Morra, O.; Nozdrin, A. A.; Olin, A.; Pantaleo, A.; Paticchio, V.; Raimondo, A.; Rossetto, E.; Rotondi, A.; Rui, R.; Salvini, P.; Sarwar, S.; Serdyuk, V.; Smith, G.; Venturelli, L.; Wheadon, R.; Yen, S.; Zenoni, A.

    1998-02-01

    The FINUDA experiment will start data taking in 1997 to study hypernuclear physics by a large acceptance. high resolution magnetic spectrometer at DA?NE, the Frascati o-factory. Physics motivations and goals besides the expected performances are described.

  5. Hypernuclear physics with stopped K- at DA?NE

    NASA Astrophysics Data System (ADS)

    Agnello, M.; Amaudruz, P. A.; Beer, G.; Benussi, L.; Bertani, M.; Bianco, S.; Botta, E.; Bressani, T.; Busso, L.; Calvo, D.; Camerini, P.; Celano, L.; Cerello, P.; D'Erasmo, G.; Fabbri, F. L.; Feliciello, A.; Filippi, A.; Filippini, V.; Fiore, E. M.; Fiore, L.; Gianotti, P.; Giardoni, M.; Gill, D. R.; Grion, N.; Guaraldo, C.; Iazzi, F.; Lanaro, A.; Lee, L.; Lucherini, V.; Marcello, S.; Marciano, G.; Minetti, B.; Mirfakhrai, N.; Morra, O.; Nozdrin, A. A.; Olin, A.; Pantaleo, A.; Paticchio, V.; Raimondo, A.; Rossetto, E.; Rotondi, A.; Rui, R.; Salvini, P.; Sarwar, S.; Serdyuk, V.; Smith, G.; Venturelli, L.; Wheadon, R.; Yen, S.; Zenoni, A.

    1997-02-01

    The FINUDA experiment will start data taking in 1997 to study hypernuclear physics by a large acceptance, high resolution magnetic spectrometer at DA?NE, the Frascati ?-factory. Physics motivations and goals besides the expected performances are described.

  6. Hypernuclear Physics with the FINUDA Spectrometer at DA?NE

    NASA Astrophysics Data System (ADS)

    Agnello, M.; Amaudruz, P. A.; Beer, G.; Benussi, L.; Bertani, M.; Bianco, S.; Botta, E.; Bressani, T.; Busso, L.; Calvo, D.; Camerini, P.; Celano, L.; Cerello, P.; D'Erasmo, G.; Fabbri, F. L.; Feliciello, A.; Filippi, A.; Filippini, V.; Fiore, E. M.; Fiore, L.; Gianotti, P.; Giardoni, M.; Gill, D. R.; Grion, N.; Guaraldo, C.; Iazzi, F.; Lanaro, A.; Lee, L.; Lucherini, V.; Marcello, S.; Marciano, G.; Minetti, B.; Montagna, P.; Mirfakhrai, N.; Morra, O.; Nozdrin, A. A.; Olin, A.; Pantaleo, A.; Paticchio, V.; Raimondo, A.; Rossetto, E.; Rotondi, A.; Rui, R.; Salvini, P.; Sarwar, S.; Serdyuk, V.; Smith, G.; Venturelli, L.; Wheadon, R.; Yen, S.; Zenoni, A.

    1997-02-01

    The FINUDA experiment will start data taking in 1997 to study hypernuclear physics by a large acceptance, high resolution magnetic spectrometer at DA?NE, the Frascati ?-factory. Physics motivations and goals besides the expected performances are described.

  7. MIGRATION FROM OPC-DA TO OPC-UA

    E-print Network

    Farnham, B

    2011-01-01

    The OPC-DA specification of OPC has been a highly successful interoperability standard for process automation since 1996, allowing communications between any compliant components regardless of vendor. CERN has a reliance on OPC-DA Server implementations from various 3rd party vendors which provide a standard interface to their hardware. The OPC foundation finalized the OPC-UA specification and OPC-UA implementations are now starting to gather momentum. This paper gives a brief overview of the headline features of OPC-UA and a comparison with OPC-DA and outlines the necessity of migrating from OPC-DA and the motivaion for migraing to OPC-UA. Feedback from research into the avaiblability of tools and testing utilities will be presented and a practical overview of what will be required from a computing perspecive in order to run OPC-UA clients and servers in the CERN network.

  8. EDITAL 008/POSJOR/2015 SELEO DA TURMA 2015 DE

    E-print Network

    Hanazaki, Natalia

    Jornalismo da Universidade Federal de Santa Catarina, no uso de suas atribuições, comunica aos candidatos Jornalismo ­ 1o andar) 14 h: Ana Paula Luckman 14h 30: Cândida de Oliveira 15 h: Criselli Maria Montipó 15 h

  9. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Hanazaki, Natalia

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO COLÉGIO DE APLICAÇÃO-09-200615-09-200615-09-200615-09-2006MARIA EDUARDA WOLF LUIZMARIA EDUARDA WOLF LUIZMARIA EDUARDA WOLF LUIZMARIA EDUARDA WOLF LUIZ 4444

  10. EDITAL 009/POSJOR/2015 SELEO DA TURMA 2015 DE

    E-print Network

    Hanazaki, Natalia

    Jornalismo da Universidade Federal de Santa Catarina, no uso de suas atribuições e em conformidade com o,25 (oito vírgula vinte e cinco) CRISELLI MARIA MONTIPÓ ­ 8,62 (oito vírgula sessenta e dois) DANIELA

  11. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true DA Form 4833 (Commander's Report of Disciplinary... Offense Reporting § 635.23 DA Form 4833 (Commander's Report of Disciplinary or Administrative Action). (a) Use. DA Form 4833 is used with DA Form 3975 to— (1) Record actions taken against identified...

  12. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true DA Form 4833 (Commander's Report of Disciplinary... Offense Reporting § 635.23 DA Form 4833 (Commander's Report of Disciplinary or Administrative Action). (a) Use. DA Form 4833 is used with DA Form 3975 to— (1) Record actions taken against identified...

  13. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false DA Form 4833 (Commander's Report of Disciplinary... Offense Reporting § 635.23 DA Form 4833 (Commander's Report of Disciplinary or Administrative Action). (a) Use. DA Form 4833 is used with DA Form 3975 to— (1) Record actions taken against identified...

  14. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false DA Form 4833 (Commander's Report of Disciplinary... Offense Reporting § 635.23 DA Form 4833 (Commander's Report of Disciplinary or Administrative Action). (a) Use. DA Form 4833 is used with DA Form 3975 to— (1) Record actions taken against identified...

  15. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true DA Form 4833 (Commander's Report of Disciplinary... Offense Reporting § 635.23 DA Form 4833 (Commander's Report of Disciplinary or Administrative Action). (a) Use. DA Form 4833 is used with DA Form 3975 to— (1) Record actions taken against identified...

  16. Novas determinações dos parâmetros atmosféricos das estrelas anãs brancas DA

    NASA Astrophysics Data System (ADS)

    Giovannini, O.; Costa, A. F. M.; Kepler, S. O.

    2003-08-01

    Nós temos selecionado uma amostra de estrelas anãs brancas DA (atmosfera de hidrogênio) a partir dos índices de Strömgren cujos valores estão próximos a região de instabilidade das estrelas anãs brancas DA variáveis, as chamadas estrelas DAV ou ZZ Ceti. O objetivo é determinar os parâmetros fundamentais (temperatura efetiva, Teff, aceleração da gravidade, log g, e massa) destas estrelas para verificar quais os parâmetros estelares estão envolvidos com o mecanismo de pulsação das estrelas DAV. Nós obtemos, até agora, mais de 120 espectros óticos de estrelas DA. Entre as estrelas selecionadas há 20 estrelas variáveis (DAV). Assim, podemos verificar se existem ou não estrelas não variáveis dentro da faixa de instabilidade das estrelas ZZ Ceti. Neste trabalho nós apresentamos a determinação dos parâmetros atmosféricos (temperatura efetiva, Teff, e aceleração da gravidade, log g) das estrelas anãs brancas DA usando os novos modelos de atmosfera ML2/a = 0.6. Estes modelos têm sido utilizados recentemente por fornecerem uma excelente consistência interna na determinação das temperaturas nas regiões do ultra-violeta e ótico. Os parâmetros atmosféricos são determinados espectroscopicamente através da comparação do fluxo de energia das linhas de Balmer (Hb à H9) entre os espectros observados e sintéticos (gerados pelos modelos de atmosfera). As temperaturas obtidas com os novos modelos são, em geral, menores (~ 1000 K menos) que as temperaturas determinadas anteriormente, com modelos ML1. Os valores de log g não mudaram significativamente (menos de 10%). A faixa de instabilidade das DAVs está entre 11000 e 13000 K, consistente com dados de outros autores.

  17. Tree branching: Leonardo da Vinci's rule versus biomechanical models.

    PubMed

    Minamino, Ryoko; Tateno, Masaki

    2014-01-01

    This study examined Leonardo da Vinci's rule (i.e., the sum of the cross-sectional area of all tree branches above a branching point at any height is equal to the cross-sectional area of the trunk or the branch immediately below the branching point) using simulations based on two biomechanical models: the uniform stress and elastic similarity models. Model calculations of the daughter/mother ratio (i.e., the ratio of the total cross-sectional area of the daughter branches to the cross-sectional area of the mother branch at the branching point) showed that both biomechanical models agreed with da Vinci's rule when the branching angles of daughter branches and the weights of lateral daughter branches were small; however, the models deviated from da Vinci's rule as the weights and/or the branching angles of lateral daughter branches increased. The calculated values of the two models were largely similar but differed in some ways. Field measurements of Fagus crenata and Abies homolepis also fit this trend, wherein models deviated from da Vinci's rule with increasing relative weights of lateral daughter branches. However, this deviation was small for a branching pattern in nature, where empirical measurements were taken under realistic measurement conditions; thus, da Vinci's rule did not critically contradict the biomechanical models in the case of real branching patterns, though the model calculations described the contradiction between da Vinci's rule and the biomechanical models. The field data for Fagus crenata fit the uniform stress model best, indicating that stress uniformity is the key constraint of branch morphology in Fagus crenata rather than elastic similarity or da Vinci's rule. On the other hand, mechanical constraints are not necessarily significant in the morphology of Abies homolepis branches, depending on the number of daughter branches. Rather, these branches were often in agreement with da Vinci's rule. PMID:24714065

  18. Tutorial de Pesquisa Bibliogrfica Este Tutorial faz parte da programao de treinamentos

    E-print Network

    Paraná, Universidade Federal do

    na área da saúde com acesso gratuito. As principais bases da área médica são: LILACS - Literatura Latino-Americana e do Caribe em Ciências da Saúde LILACS é um índice bibliográfico da literatura relativa da base Scielo. LILACS também indexa outros tipos de literatura científica e técnica como teses

  19. Mevalocidin: a novel, phloem mobile phytotoxin from Fusarium DA056446 and Rosellinia DA092917.

    PubMed

    Gerwick, B Clifford; Brewster, William K; Deboer, Gerrit J; Fields, Steve C; Graupner, Paul R; Hahn, Donald R; Pearce, Cedric J; Schmitzer, Paul R; Webster, Jeffery D

    2013-02-01

    A multiyear effort to identify new natural products was built on a hypothesis that both phytotoxins from plant pathogens and antimicrobial compounds might demonstrate herbicidal activity. The discovery of one such compound, mevalocidin, is described in the current report. Mevalocidin was discovered from static cultures of two unrelated fungal isolates designated Rosellinia DA092917 and Fusarium DA056446. The chemical structure was confirmed by independent synthesis. Mevalocidin demonstrated broad spectrum post-emergence activity on grasses and broadleaves and produced a unique set of visual symptoms on treated plants suggesting a novel mode of action. Mevalocidin was rapidly absorbed in a representative grass and broadleaf plant. Translocation occurred from the treated leaf to other plant parts including roots confirming phloem as well as xylem mobility. By 24 hr after application, over 20 % had been redistributed through-out the plant. Mevalocidin is a unique phytotoxin based on its chemistry, with the uncommon attribute of demonstrating both xylem and phloem mobility in grass and broadleaf plants. PMID:23314893

  20. Boso de Higgs recebe Nobel da Fsica no ano a seguir descoberta p29 Nobel da Fsica de 2013 para teoria

    E-print Network

    Instituto de Sistemas e Robotica

    Gerschenfeltl François Englert (80 anos), da Uni- versidade Livre de Bruxelas, na Bél- gica, e Peter Higgs (84 anos), da altíssima energia do LHC. Num comunicado emitido pouco depois do anúncio, o CERN, que fi- cou fora do Nobel

  1. Divulgamos a lista de associados pais/mes/responsveis, em virtude do processo eleitoral para escolha da nova diretoria da APP que ser aberto em breve. Qualquer

    E-print Network

    Hanazaki, Natalia

    escolha da nova diretoria da APP que será aberto em breve. Qualquer divergência, entre em contato. ASSOCIADOS APP ­ PAIS/MÃES/RESPONSÁVEIS ATÉ SETEMBRO DE 2013 ASSOCIADOS - APP CA/UFSC 1. ABIGAIL SILVA DE

  2. 76 FR 12627 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42...in-flight loss of a rear passenger door on Diamond aeroplanes, the majority of which were...because of damage found on the hinge. Diamond Aircraft Industries conducted...

  3. 76 FR 27861 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42...in-flight loss of a rear passenger door on Diamond aeroplanes, the majority of which were...because of damage found on the hinge. Diamond Aircraft Industries conducted...

  4. Overview of ATLAS PanDA Workload Management

    SciTech Connect

    Maeno T.; De K.; Wenaus T.; Nilsson P.; Stewart G. A.; Walker R.; Stradling A.; Caballero J.; Potekhin M.; Smith D.

    2011-01-01

    The Production and Distributed Analysis System (PanDA) plays a key role in the ATLAS distributed computing infrastructure. All ATLAS Monte-Carlo simulation and data reprocessing jobs pass through the PanDA system. We will describe how PanDA manages job execution on the grid using dynamic resource estimation and data replication together with intelligent brokerage in order to meet the scaling and automation requirements of ATLAS distributed computing. PanDA is also the primary ATLAS system for processing user and group analysis jobs, bringing further requirements for quick, flexible adaptation to the rapidly evolving analysis use cases of the early datataking phase, in addition to the high reliability, robustness and usability needed to provide efficient and transparent utilization of the grid for analysis users. We will describe how PanDA meets ATLAS requirements, the evolution of the system in light of operational experience, how the system has performed during the first LHC data-taking phase and plans for the future.

  5. Recent Improvements in the ATLAS PanDA Pilot

    NASA Astrophysics Data System (ADS)

    Nilsson, P.; Caballero Bejar, J.; Compostella, G.; Contreras, C.; De, K.; Dos Santos, T.; Maeno, T.; Potekhin, M.; Wenaus, T.

    2012-12-01

    The Production and Distributed Analysis system (PanDA) in the ATLAS experiment uses pilots to execute submitted jobs on the worker nodes. The pilots are designed to deal with different runtime conditions and failure scenarios, and support many storage systems. This talk will give a brief overview of the PanDA pilot system and will present major features and recent improvements including CernVM File System integration, the job retry mechanism, advanced job monitoring including JEM technology, and validation of new pilot code using the HammerCloud stress-testing system. PanDA is used for all ATLAS distributed production and is the primary system for distributed analysis. It is currently used at over 130 sites worldwide. We analyze the performance of the pilot system in processing LHC data on the OSG, EGI and Nordugrid infrastructures used by ATLAS, and describe plans for its further evolution.

  6. Geomagnetic observations on tristan da cunha, south atlantic ocean

    USGS Publications Warehouse

    Matzka, J.; Olsen, N.; Maule, C.F.; Pedersen, L.W.; Berarducci, A.M.; Macmillan, S.

    2009-01-01

    Few geomagnetic ground observations exist of the Earth's strongest core field anomaly, the South Atlantic Anomaly (SAA). The geomagnetic repeat station on the island Tristan da Cunha, located half-way between South Africa and South America at 37?? 05' S, 12?? 18' W, is therefore of crucial importance. We have conducted several sets of repeat station measurements during magnetically quiet conditions (Kp 2o or less) in 2004. The procedures are described and the results are compared to those from earlier campaigns and to the predictions of various global field models. Features of the local crustal bias field and the solar quiet daily variation are discussed. We also evaluate the benefit of continuous magnetic field recordings from Tristan da Cunha, and argue that such a data set is a very valuable addition to geomagnetic satellite data. Recently, funds were set up to establish and operate a magnetometer station on Tristan da Cunha during the Swarm magnetic satellite mission (2011-2014).

  7. Integration Of PanDA Workload Management System With Supercomputers

    E-print Network

    Klimentov, Alexei; The ATLAS collaboration; Maeno, Tadashi; Mashinistov, Ruslan; Nilsson, Paul; Oleynik, Danila; Panitkin, Sergey; Read, Kenneth; Ryabinkin, Evgeny; Wenaus, Torre

    2015-01-01

    The Large Hadron Collider (LHC), operating at the international CERN Laboratory in Geneva, Switzerland, is leading Big Data driven scientific explorations. Experiments at the LHC explore the fundamental nature of matter and the basic forces that shape our universe, and were recently credited for the discovery of a Higgs boson. ATLAS, one of the largest collaborations ever assembled in the sciences, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. The ATLAS experiment uses PanDA (Production and Data Analysis) Workload Management System for managing the workflow for all data processing on over 140 data centers. Through PanDA, ATLAS physicists see a single computing facility that enables rapid scientific breakthroughs for the experiment, even though the data centers are physically scattered all over the world. While PanDA currently uses more than 100,000 co...

  8. Departamento de Matem'atica da Universidade de Coimbra An'alise Num'erica I

    E-print Network

    Pascoal, Marta Margarida Braz

    Departamento de Matem'atica da Universidade de Coimbra An'alise Num'erica I Ano lectivo 1999'atica da Universidade de Coimbra An'alise Num'erica I Ano lectivo 1999/2000 Teste 1 -----\\Pi----- Considere

  9. 40 CFR 60.48Da - Compliance provisions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Specification 1 in 40 CFR part 60, appendix B. (ii) You must comply with the quality assurance requirements in... of Performance Specification 1 in 40 CFR part 60, appendix B. (B) You must adjust the zero and span... using the CEMS specified under § 60.49Da for measuring NOX and oxygen (O2) (or carbon dioxide (CO2))...

  10. Studying and Working Abroad. Leonardo da Vinci Series: Good Practices.

    ERIC Educational Resources Information Center

    Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

    This document profiles recent successful examples of students studying and working abroad as part of the European Commission's Leonardo da Vinci program, which is designed to give students across the European Union the opportunity to experience vocational training in a foreign country. The following examples are presented: (1) 3 Finnish students…

  11. Anurio Estatstico da UnB Perodo: 2010 a 2014

    E-print Network

    Maier, Rudolf Richard

    NOVO Anuário Estatístico da UnB 2015 Período: 2010 a 2014 UNIVERSIDADE DE BRASÍLIA DECANATO DE Reitor: Professor Ivan Marques de Toledo Camargo Vice-Reitora: Professora Sônia Nair Báo Decano de de Carvalho Decano de Graduação: Professor Mauro Luiz Rabelo Decana de Extensão: Professora Thérèse

  12. TEODOLINDA BAROLINI Lorenzo Da Ponte Professor of Italian

    E-print Network

    Qian, Ning

    TEODOLINDA BAROLINI Lorenzo Da Ponte Professor of Italian Department of Italian 510 Hamilton Hall Columbia University New York, NY 10027 (212) 854-2312 tb27@columbia.edu http://italian.columbia.edu/people/profile/1478 EDUCATION Columbia University, 1972-1978 o M.A. Italian, 1973 o Ph.D. Italian and Comparative

  13. IDIAS ACESASIDIAS ACESAS Jornal da Unicamp traz na lti-

    E-print Network

    de Aguiar, Marcus A. M.

    - lho, por conta do racionamento de energia. São esperados outros dois impac- tos sobre o mercado de haverá energia para suportar a ampliação da capaci- dade instalada no Brasil. Declarações de grandes energia elé- trica. Mais uma vez, quem arcará com as conseqüências é a população. "A energia elétrica é

  14. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO a participação dos seguintes profissionais do NDI: coordenadora pedagógica Sonia Maria Jordão de Castro; pedagoga Joyce Regina Borges; professoras Graziela Maria Beretta López e Thaisa Neiverth. 3. Informamos que o

  15. UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CINCIAS DA EDUCAO

    E-print Network

    Floeter, Sergio Ricardo

    UNIVERSIDADE FEDERAL DE SANTA CATARINA CENTRO DE CIÊNCIAS DA EDUCAÇÃO NÚCLEO DE DESENVOLVIMENTO Federal de Santa Catarina. Florianópolis: 2002. 102 p. STRENZEL, Giandréa R. et al. "Educação Infantil. RAUPP, Marilene D.; LAFFIN, Maria H. F. ; DURLI, Zenilde (Orgs.). A Formação de Professores para

  16. Galapagos sharks (Carcharhinus galapagensis) at the Bassas da

    E-print Network

    Galapagos sharks (Carcharhinus galapagensis) at the Bassas da India atoll: first record from Introduction The Galapagos shark, Carcharhinus galapagensis,1 is circum- tropical in its distribution; however and species identification During October 2003, a shark diversity survey was conducted at several locations

  17. Introduc ~ao `a Teoria da Medida e Integral de Lebesgue

    E-print Network

    Cabral, Marco

    Dominada, Fubini, derivada de Radon-Nikod´ym, espa¸co produto. Por isso inclu´imos estes resultados://dsl.org/copyleft/dsl.txt. Recomendamos como leitura complementar o livro do Bartle (Elements of Integration, ver Bibliografia) por ser um Radon-Nikod´ym e Fubini . . . . . . . . . . . . . . . . . . . . . 32 2.6 Outras Constru¸c~oes da

  18. 40 CFR 60.45Da - Standard for mercury (Hg).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Standard for mercury (Hg). 60.45Da... for mercury (Hg). (a) For each coal-fired electric utility steam generating unit other than an IGCC... gases that contain mercury (Hg) emissions in excess of each Hg emissions limit in paragraphs...

  19. 40 CFR 60.45Da - Standard for mercury (Hg).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Standard for mercury (Hg). 60.45Da... for mercury (Hg). (a) For each coal-fired electric utility steam generating unit other than an IGCC... gases that contain mercury (Hg) emissions in excess of each Hg emissions limit in paragraphs...

  20. The DaVinci Project: Multimedia in Art and Chemistry.

    ERIC Educational Resources Information Center

    Simonson, Michael; Schlosser, Charles

    1998-01-01

    Provides an overview of the DaVinci Project, a collaboration of students, teachers, and researchers in chemistry and art to develop multimedia materials for grades 3-12 visualizing basic concepts in chemistry and visual art. Topics addressed include standards in art and science; the conceptual framework for the project; and project goals,…

  1. The Potential da Vinci in All of Us

    ERIC Educational Resources Information Center

    Petto, Sarah; Petto, Andrew

    2009-01-01

    The study of the human form is fundamental to both science and art curricula. For vertebrates, perhaps no feature is more important than the skeleton to determine observable form and function. As Leonard da Vinci's famous Proportions of the Human Figure (Virtruvian Man) illustrates, the size, shape, and proportions of the human body are defined by…

  2. The Future of PanDA in ATLAS Distributed Computing

    E-print Network

    De, Kaushik; The ATLAS collaboration; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Panitkin, Sergey; Petrosyan, Artem; Schovancova, Jaroslava; Vaniachine, Alexandre; Wenaus, Torre

    2015-01-01

    Experiments at the Large Hadron Collider (LHC) face unprecedented computing challenges. Heterogeneous resources are distributed worldwide at hundreds of sites, thousands of physicists analyze the data remotely, the volume of processed data is beyond the exabyte scale, while data processing requires more than a few billion hours of computing usage per year. The PanDA (Production and Distributed Analysis) system was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. In the process, the old batch job paradigm of locally managed computing in HEP was discarded in favor of a far more automated, flexible and scalable model. The success of PanDA in ATLAS is leading to widespread adoption and testing by other experiments. PanDA is the first exascale workload management system in HEP, already operating at more than a million computing jobs per day, and processing over an exabyte of data in 2013. There are many new challenges that PanDA will face in the near future, in addi...

  3. Training and Health. Leonardo da Vinci Series: Good Practices.

    ERIC Educational Resources Information Center

    Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

    This document profiles programs in the fields of health and medicine that are offered through the European Commission's Leonardo da Vinci program. The following programs are profiled: (1) CYTOTRAIN (a transnational vocational training program in cervical cancer screening); (2) Apollo (a program of open and distance learning for paramedical…

  4. Women and Technical Professions. Leonardo da Vinci Series: Good Practices.

    ERIC Educational Resources Information Center

    Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

    This document profiles programs for women in technical professions that are offered through the European Commission's Leonardo da Vinci program. The following programs are profiled: (1) Artemis and Diana (vocational guidance programs to help direct girls toward technology-related careers); (2) CEEWIT (an Internet-based information and…

  5. A Situação Social da Mulher no Teatro de Consuelo de Castro e Leilah Assunção

    E-print Network

    Barros, Alcides J. de.

    1976-04-01

    passa o tempo bebendo whisky à beira da piscina ou esbanjando dinheiro com diversões noturnas. Essa atitude adolescente só poderia ter o desfecho que teve: incapaz de destruir o mundo e não sabendo como fazer para moldá-lo de acordo com seus próprios... da sociedade de consumo, "o processo de alienação da dignidade individual diante do engajamento de produção numa sociedade."8 Marisa da Penha é uma moça que trabalha numa agência de publicidade, onde tenta ganhar suficiente dinheiro para que seu...

  6. Solving da Vinci stereopsis with depth-edge-selective V2 cells Andrew Assee *, Ning Qian *

    E-print Network

    Qian, Ning

    Solving da Vinci stereopsis with depth-edge-selective V2 cells Andrew Assee *, Ning Qian * Center; received in revised form 22 June 2007 Abstract We propose a new model for da Vinci stereopsis based of a monocular bar next to a binocular rect- angle may not be da Vinci stereopsis per se [Gillam, B., Cook, M

  7. Cutaneous Feedback of Planar Fingertip Deformation and Vibration on a da Vinci Surgical Robot

    E-print Network

    Siena, Università di

    Cutaneous Feedback of Planar Fingertip Deformation and Vibration on a da Vinci Surgical Robot da Vinci Si), but current surgical robots have very limited haptic feedback, despite its expected to leave only the cutaneous cues. This paper presents a novel cutaneous feedback system for the da Vinci

  8. Yarkovsky-driven Impact Predictions: Apophis and 1950 DA

    NASA Astrophysics Data System (ADS)

    Chesley, Steven R.; Farnocchia, D.; Chodas, P. W.; Milani, A.

    2013-10-01

    Orbit determination for Near-Earth Asteroids presents unique technical challenges due to the imperative of early detection and careful assessment of the risk posed by specific Earth close approaches. The occurrence of an Earth impact can be decisively driven by the Yarkovsky effect, which is the most important nongravitational perturbation as it causes asteroids to undergo a secular variation in semimajor axis resulting in a quadratic effect in anomaly. We discuss the cases of (99942) Apophis and (29075) 1950 DA. The relevance of the Yarkovsky effect for Apophis is due to a scattering close approach in 2029 with minimum geocentric distance ~38000 km. For 1950 DA the influence of the Yarkovsky effect in 2880 is due to the long time interval preceding the impact. We use the available information from the astrometry and the asteroids' physical models and dynamical evolution as a starting point for a Monte Carlo method that allows us to measure how the Yarkovsky effect affects orbital predictions. We also find that 1950 DA has a 98% likelihood of being a retrograde rotator. For Apophis we map onto the 2029 close approach b-plane and analyze the keyholes corresponding to resonant close approaches. For 1950 DA we use the b-plane corresponding to the possible impact in 2880. We finally compute the impact probability from the mapped probability density function on the considered b-plane. For Apophis we have 4 in a million chances of an impact in 2068, while the probability of Earth impact in 2880 for 1950 DA is 0.04%.

  9. 75 FR 75868 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40 and DA 40F Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40...information identified in this AD, contact Diamond Aircraft Industries GmbH, N.A. Otto-Stra...43 2622 26780; e-mail: office@diamond-air.at; Internet:...

  10. ATA N. 103 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Cincias da Educao. Ata da centsima1

    E-print Network

    Floeter, Sergio Ricardo

    ATA N. 103 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Ciências da. Estavam3 presentes: a coordenadora pedagógica: Sônia Maria Jordão de Castro; as professoras efetivas:4 Caroline Machado Momm, Débora Cristina de Sampaio Peixe, Graziela Maria Beretta López,5 Jodete Bayer Gomes

  11. ATA N. 98 / COLEGIADO / 2011 Universidade Federal de Santa Catarina, Centro de Cincias da Educao. Ata da nonagsima1

    E-print Network

    Floeter, Sergio Ricardo

    ATA N. 98 / COLEGIADO / 2011 Universidade Federal de Santa Catarina, Centro de Ciências da Educação Machado Momm, Débora Cristina de Sampaio Peixe,6 Giandréa Reuss Strenzel, Graziela Maria Beretta Lopez representante das famílias: Carlos Henrique Lemos Soares. Justificaram ausência:12 as professoras Sônia Maria

  12. ATA N. 96 / COLEGIADO / 2011 Universidade Federal de Santa Catarina, Centro de Cincias da Educao. Ata da nonagsima1

    E-print Network

    Floeter, Sergio Ricardo

    ATA N. 96 / COLEGIADO / 2011 Universidade Federal de Santa Catarina, Centro de Ciências da Educação, Graziela Maria Beretta López, Jodete Bayer Gommes Fullgraf,7 Josiana Piccolli, Juliane Mendes Rosa La Banca, Pricilla Cristine Trierweiller, Regina Ingrid8 Bragagnolo, Rose Elaine de Liz Waltrick, Sandra Maria

  13. ATA N. 105 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Cincias da Educao. Ata da centsima1

    E-print Network

    Floeter, Sergio Ricardo

    ATA N. 105 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Ciências da pedagógica: Sônia Maria Jordão de Castro; as professoras efetivas: Carolina Shimomura Spinelli,5 Débora; as professoras: Graziela11 Maria Beretta Lópeze e Pricilla Cristine Trierweiller. A presidente inicia a reunião

  14. ATA N. 104 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Cincias da Educao. Ata da centsima1

    E-print Network

    Floeter, Sergio Ricardo

    ATA N. 104 / COLEGIADO / 2012 Universidade Federal de Santa Catarina, Centro de Ciências da pedagógica: Sônia Maria Jordão de Castro; as professoras efetivas: Carolina Shimomura Spinelli,5 Débora Cristina de Sampaio Peixe, Giandréa Reuss Strenzel, Gisele Day, Graziela Maria Beretta6 López, Jodete Bayer

  15. DA-9801 promotes neurite outgrowth via ERK1/2-CREB pathway in PC12 cells.

    PubMed

    Won, Jong Hoon; Ahn, Kyong Hoon; Back, Moon Jung; Ha, Hae Chan; Jang, Ji Min; Kim, Ha Hyung; Choi, Sang-Zin; Son, Miwon; Kim, Dae Kyong

    2015-01-01

    In the present study, we examined the mechanisms underlying the effect of DA-9801 on neurite outgrowth. We found that DA-9801 elicits its effects via the mitogen-activated protein kinase (MEK) extracellular signal-regulated kinase (ERK)1/2-cAMP response element-binding protein (CREB) pathway. DA-9801, an extract from a mixture of Dioscorea japonica and Dioscorea nipponica, was reported to promote neurite outgrowth in PC12 cells. The effects of DA-9801 on cell viability and expression of neuronal markers were evaluated in PC12 cells. To investigate DA-9801 action, specific inhibitors targeting the ERK signaling cascade were used. No cytotoxicity was observed in PC12 cells at DA-9801 concentrations of less than 30 µg/mL. In the presence of nerve growth factor (NGF, 2 ng/mL), DA-9801 promoted neurite outgrowth and increased the relative mRNA levels of neurofilament-L (NF-L), a marker of neuronal differentiation. The Raf-1 inhibitor GW5074 and MEK inhibitor PD98059 significantly attenuated DA-9801-induced neurite outgrowth. Additionally, the MEK1 and MEK2 inhibitor SL327 significantly attenuated the increase in the percentage of neurite-bearing PC12 cells induced by DA-9801 treatment. Conversely, the selective p38 mitogen-activated protein kinase inhibitor SB203580 did not attenuate the DA-9801 treatment-induced increase in the percentage of neurite-bearing PC12 cells. DA-9801 enhanced the phosphorylation of ERK1/2 and CREB in PC12 cells incubated with and without NGF. Pretreatment with PD98059 blocked the DA-9801-induced phosphorylation of ERK1/2 and CREB. In conclusion, DA-9801 induces neurite outgrowth by affecting the ERK1/2-CREB signaling pathway. Insights into the mechanism underlying this effect of DA-9801 may suggest novel potential strategies for the treatment of peripheral neuropathy. PMID:25482167

  16. TA-DA: A TOOL FOR ASTROPHYSICAL DATA ANALYSIS

    SciTech Connect

    Da Rio, Nicola; Robberto, Massimo

    2012-12-01

    We present the Tool for Astrophysical Data Analysis (TA-DA), a new software aimed to greatly simplify and improve the analysis of stellar photometric data in comparison with theoretical models, and allow the derivation of stellar parameters from multi-band photometry. Its flexibility allows one to address a number of such problems: from the interpolation of stellar models, or sets of stellar physical parameters in general, to the computation of synthetic photometry in arbitrary filters or units; from the analysis of observed color-magnitude diagrams to a Bayesian derivation of stellar parameters (and extinction) based on multi-band data. TA-DA is available as a pre-compiled Interactive Data Language widget-based application; its graphical user interface makes it considerably user-friendly. In this paper, we describe the software and its functionalities.

  17. [Lobectomy for lung cancer using the Da Vinci surgical system].

    PubMed

    Nakamura, Hiroshige

    2014-05-01

    Robot-assisted surgery using the da Vinci surgical system has attracted attention because of excellent operability without shaking by joint forceps under the clear vision of a three-dimensional high-definition camera in lung cancer surgery. Although this form of advanced medical care is not yet approved for insurance coverage, it is at the stage of clinical research and expected to be useful in hilar exposure, lymph node dissection, and suturing of the lung parenchyma or bronchus. Lung cancer surgery with the da Vinci system has the advantage of combining thoracotomy and minimally invasive surgery in video-assisted thoracic surgery. However, safety management, education, and significant cost are problems to be resolved. Several important issues such as sharing knowledge and technology of robotic surgery, education, training, development of new instruments, and acquisition of advanced medical insurance are discussed for the future development of robotic surgical systems. PMID:24946522

  18. TUTORIAL DE PESQUISA BIBLIOGRTUTORIAL DE PESQUISA BIBLIOGRTUTORIAL DE PESQUISA BIBLIOGRTUTORIAL DE PESQUISA BIBLIOGRFICAFICAFICAFICA Este tutorial faz parte da programao de treinamentos da Biblioteca de Cincias daBiblioteca de Cincias daBiblioteca de Cinc

    E-print Network

    Paraná, Universidade Federal do

    SaSaSaúúúúdededede ­­­­ SdSdSdSd da Universidade Federal do Paranda Universidade Federal do Paranda Universidade Federal do Paranda Universidade Federal do Paranáááá.... Serve como material de apoio e não possui fins lucrativos 11111111 3.1 Online Search3.1 Online Search3.1 Online Search3.1 Online Search ---- Pesquisa Online

  19. Plug flow formation and growth in da Vinci Fluids

    E-print Network

    Moshe Schwartz; Raphael Blumenfeld

    2010-04-22

    A new, da Vinci, fluid is described as a model for flow of dense granular matter. We postulate local properties of the fluid, which are generically different from ordinary fluids in that energy is dissipated by solid friction. We present the equation of flow of such a fluid and show that it gives rise to formation and growth of plug flow regions, which is characteristic of flow of granular matter. Simple explicit examples are presented to illustrate the evolution of plug flow regions.

  20. Identification of an abundant 56 kDa protein implicated in food allergy as granule-bound starch synthase

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Rice, the staple food of South and East Asian counties, is considered to be hypoallergenic. However, several clinical studies have documented rice-induced allergy in sensitive patients. Rice proteins with molecular weights of 14-16 kDa, 26 kDa, 33 kDa and 56 kDa have been identified as allergens. Re...

  1. The ATLAS PanDA Pilot in Operation

    NASA Astrophysics Data System (ADS)

    Nilsson, P.; Caballero, J.; De, K.; Maeno, T.; Stradling, A.; Wenaus, T.; ATLAS Collaboration

    2011-12-01

    The Production and Distributed Analysis system (PanDA) [1-2] was designed to meet ATLAS [3] requirements for a data-driven workload management system capable of operating at LHC data processing scale. Submitted jobs are executed on worker nodes by pilot jobs sent to the grid sites by pilot factories. This paper provides an overview of the PanDA pilot [4] system and presents major features added in light of recent operational experience, including multi-job processing, advanced job recovery for jobs with output storage failures, gLExec [5-6] based identity switching from the generic pilot to the actual user, and other security measures. The PanDA system serves all ATLAS distributed processing and is the primary system for distributed analysis; it is currently used at over 100 sites worldwide. We analyze the performance of the pilot system in processing real LHC data on the OSG [7], EGI [8] and Nordugrid [9-10] infrastructures used by ATLAS, and describe plans for its evolution.

  2. Análise da medição do raio solar em ultravioleta

    NASA Astrophysics Data System (ADS)

    Saraiva, A. C. V.; Giménez de Castro, C. G.; Costa, J. E. R.; Selhorst, C. L.; Simões, P. J. A.

    2003-08-01

    A medição acurada do raio solar em qualquer banda do espectro eletromagnético é de relevância na formulação e calibração de modelos da estrutura e atmosfera solar. Esses modelos atribuem emissão do contínuo do Sol calmo em microondas à mesma região da linha Ha do Hell. Apresentamos a medição do raio solar em UV com imagens do EIT (Extreme Ultraviolet Image Telescope) entre 1996 e 2002, no comprimento de onda 30,9 nm (Ha do Hell), que se forma na região de transição/cromosfera solar. A técnica utilizada para o cálculo do raio UV foi baseada na transformada Wavelet B3spline. Fizemos um banco de dados com 1 imagem por dia durante o período citado. Obtivemos como resultado o raio médio da ordem de 975.61" e uma diminuição do mesmo para o período citado variando em média -0,45" /ano. Comparamos estes dados com os valores obtidos pelo ROI (Radio Observatório de Itapetinga) em 22/48 GHz e Nobeyama Radio Heliograph em 17 GHz mostrando que os raios médios são muito próximos o que indica que a região de formação nessas freqüências é a mesma conforme os modelos. Comparamos os resultados também com outros índices de atividade solar.

  3. Amelioration of Auditory Response by DA9801 in Diabetic Mouse.

    PubMed

    Lee, Yeong Ro; Hong, Bin Na; Her, You Ri; Castañeda, Rodrigo; Moon, Hyo Won; Kang, Tong Ho

    2015-01-01

    Diabetes mellitus (DM) is a metabolic disease that involves disorders such as diabetic retinopathy, diabetic neuropathy, and diabetic hearing loss. Recently, neurotrophin has become a treatment target that has shown to be an attractive alternative in recovering auditory function altered by DM. The aim of this study was to evaluate the effect of DA9801, a mixture of Dioscorea nipponica and Dioscorea japonica extracts, in the auditory function damage produced in a STZ-induced diabetic model and to provide evidence of the mechanisms involved in enhancing these protective effects. We found a potential application of DA9801 on hearing impairment in the STZ-induced diabetic model, demonstrated by reducing the deterioration produced by DM in ABR threshold in response to clicks and normalizing wave I-IV latencies and Pa latencies in AMLR. We also show evidence that these effects might be elicited by inducing NGF related through Nr3c1 and Akt. Therefore, this result suggests that the neuroprotective effects of DA9801 on the auditory damage produced by DM may be affected by NGF increase resulting from Nr3c1 via Akt transformation. PMID:25878713

  4. Yarkovsky-driven Impact Predictions: Apophis and 1950 DA

    NASA Astrophysics Data System (ADS)

    Farnocchia, Davide; Chesley, S. R.; Chodas, P.; Milani, A.

    2013-05-01

    Abstract (2,250 Maximum Characters): Orbit determination for Near-Earth Asteroids presents unique technical challenges due to the imperative of early detection and careful assessment of the risk posed by specific Earth close approaches. The occurrence of an Earth impact can be decisively driven by the Yarkovsky effect, which is the most important nongravitational perturbation as it causes asteroids to undergo a secular variation in semimajor axis resulting in a quadratic effect in anomaly. We discuss the cases of (99942) Apophis and (29075) 1950 DA. The relevance of the Yarkovsky effect for Apophis is due to a scattering close approach in 2029 with minimum geocentric distance ~38000 km. For 1950 DA the influence of the Yarkovsky effect in 2880 is due to the long time interval preceding the impact. We use the available information on the asteroids' physical models as a starting point for a Monte Carlo method that allow us to measure how the Yarkovsky effect affects orbital predictions. For Apophis we map onto the 2029 close approach b-plane and analyze the keyholes corresponding to resonant close approaches. For 1950 DA we use the b-plane corresponding to the possible impact in 2880. We finally compute the impact probability from the mapped probability density function on the considered b-plane.

  5. The DaVinci Group: a second modern Ophthalmotrope.

    PubMed

    Pruehsner, William R; Enderle, John D

    2006-01-01

    A group of undergraduate students at the University of Connecticut Biomedical Engineering Program has formed a "club" in order to more fully understand and educate themselves in modeling anatomical processes. This group is called the DaVinci Robot or DaVinci Group. Experiments to mechanically model the six extraocular muscles of the eye have been performed, each meeting little success. While researching methods that would lead to better success, the concept of the Ophthalmotrope was discovered. The Ophthalmotrope is a mechanical visual aide used in teaching the function of the extraocular muscles, prevalent in the mid 1800's. The Group decided to study this device and ultimately decided to build one. The paper presented here discusses our third experiment, currently under investigation, that is, to build an Opthalmotrope. Difficulties with this task are lack of any information with regard to how to construct this device. Presented are descriptions of the Group's initial experiments and research conducted into the construction of the Ophthalmotrpe. In the main body of the presented paper is a description of how the DaVinci Group Ophthalmotrope is constructed. Concluding is a discussion of the progress of the construction of the Ophthalmotrope along with a brief listing of research conducted in order to build the device. PMID:16817648

  6. Seeking 'energy' vs. pain relief in spas in Brazil (Caldas da Imperatriz) and Portugal (Termas da Sulfurea).

    PubMed

    Quintela, Maria Manuel

    2011-04-01

    This paper is a comparative ethnography of the therapeutic practices at two different spa locations: Caldas da Imperatriz, SC, Brazil, and Termas da Sulfurea in Cabeco de Vide, Portugal. The comparison reveals the existence of contrasting 'explanatory models' held by the spa-goers as well as by the official medical systems. In the Portuguese context this model is highly medicalized; in the Brazilian case, spa treatments are viewed as 'alternative' or 'complementary' therapy and are also related to religious philosophies. Each model corresponds to a different idiom expressing certain experiences and world views, one focusing on 'pains' (dores) and the other on 'energy' (energia), the former leading to the rationale of 'curing', the latter to the notion of 'energizing'. In this paper the author intends to analyze and contrast the categories found in these models, which originate from different conceptions of health, illness and healing for Brazilian and Portuguese spa-goers. PMID:21563001

  7. Ci sta, ci sta. inutile che ridete, stronzi. Ci sta perch io ci so fare. Io trombo da dio. Io rimbombo, da come trombo. Ragazzi,

    E-print Network

    Frosini, Patrizio

    Ciriatto «Ci sta, ci sta. È inutile che ridete, stronzi. Ci sta perché io ci so fare. Io trombo da dio. Io rimbombo, da come trombo. Ragazzi, l'ho fatta innamorare alla prima scopata. È pazza di me tornare alla base. Lei si mette a ridere e io capisco subito: è fatta. Siamo andati insieme al Bar

  8. A Direo do Ncleo de Desenvolvimento Infantil do Centro de Cincias da Educao da Universidade Federal de Santa Catarina, no uso de suas atribuies e, tendo em vista

    E-print Network

    Floeter, Sergio Ricardo

    Federal de Santa Catarina, no uso de suas atribuições e, tendo em vista o que dispõe o edital n.01/NDI/04/2011 a 31/03/2012) 1. Alice da Silva Magnus 2. Antonio Maria Marçal Telo Nunes da Costa 3. Gustavo Reis

  9. The 29-kDa proteins phosphorylated ion thrombin-activated human platelets are forms of the estrogen receptor-related 27-kDa heat shock protein

    SciTech Connect

    Mendelsohn, M.E.; Yan Zhu; O'Neill, S. )

    1991-12-15

    Thrombin plays a critical role in platelet activation, hemostasis, and thrombosis. Cellular activation by thrombin leads to the phosphorylation of multiple proteins, most of which are unidentified. The authors have characterized several 29-kDa proteins that are rapidly phosphorylated following exposure of intact human platelets to thrombin. A murine monoclonal antibody raised to an unidentified estrogen receptor-related 29-kDa protein selectively recognized these proteins as well as a more basic, unphosphorylated 27-kDa protein. Cellular activation by thrombin led to a marked shift in the proportion of protein from the 27-kDa unphosphorylated form to the 29-kDa phosphoprotein species. Using this antibody, they isolated and sequenced a human cDNA clone encoding a protein that was identical to the mammalian 27-kDa heat shock protein (HSP27), a protein of uncertain function that is known to be phosphorylated to several forms and to be transcriptionally induced by estrogen. The 29-kDa proteins were confirmed to be phosphorylated forms of HSP27 by immunoprecipitation studies. Thus, the estrogen receptor-related protein is HSP27, and the three major 20-kDa proteins phosphorylated in thrombin-activated platelets are forms of HSP27. These data suggest a role for HSP27 in the signal transduction events of platelet activation.

  10. a) Da R konvergent ist, brauchen wir nur app(y, nil) und y zu Normalformen auszuwerten und auf Gleichheit zu testen. Da die beiden Terme bereits in

    E-print Network

    Ábrahám, Erika

    Aufgabe 1 a) Da R konvergent ist, brauchen wir nur app(y, nil) und y zu Normalformen auszuwerten und auf Gleichheit zu testen. Da die beiden Terme bereits in Normalform sind, gilt E #|= app(y, nil) # y. b) Wir nutzen das Verfahren der impliziten Induktion mit der LPO mit app # cons, um E |= I app

  11. a) Da R konvergent ist, brauchen wir nur app(y, nil) und y zu Normalformen auszuwerten und auf Gleichheit zu testen. Da die beiden Terme bereits in

    E-print Network

    Ábrahám, Erika

    Aufgabe 1 a) Da R konvergent ist, brauchen wir nur app(y, nil) und y zu Normalformen auszuwerten und auf Gleichheit zu testen. Da die beiden Terme bereits in Normalform sind, gilt E |= app(y, nil) y. b) Wir nutzen das Verfahren der impliziten Induktion mit der LPO mit app cons, um E |=I app(y, nil

  12. Relatrio Final da licenciatura em Matemtica Aplicada e Computao

    E-print Network

    Cannas da Silva, Ana

    -se a boa organização da visita que, conjuntamente com a clareza do Relatório de Auto-Avaliação, em muito docente (com melhorias em relação à já boa situação detectada no 1o ciclo de avaliação), as boas condições de trabalho, a qualidade dos candidatos e a boa relação entre docentes e discentes. 2. A necessidade

  13. Mammary artery harvesting using the Da Vinci Si robotic system

    PubMed Central

    Canale, Leonardo Secchin; Bonatti, Johannes

    2014-01-01

    Internal mammary artery harvesting is an essential part of any coronary artery bypass operation. Totally endoscopic coronary artery bypass graft surgery has become reality in many centers as a safe and effective alternative to conventional surgery in selected patients. Internal mammary artery harvesting is the initial part of the procedure and should be performed equally safely if one wants to achieve excellence in patency rates for the bypass. We here describe the technique for mammary harvesting with the Da Vinci Si robotic system. PMID:24896171

  14. Da Vinci's codex and the anatomy of healthcare.

    PubMed

    Stephens-Borg, Keith

    2012-08-01

    We usually display a laid-back approach to medical jargon throughout our theatre work. The word 'perioperative' is built from the Greek word 'peri' (around) and the Latin 'operari' (to work). Latin and Greek became the prefixed language of choice for Leonardo da Vinci, and his research was pivotal in determining the way in which surgical procedures are documented. Ancient manuscripts aided the unfolding of the secrets of anatomy, and Leonardo revealed that art was the key in expressive detailed explanation. PMID:23248927

  15. Visual tracking of da Vinci instruments for laparoscopic surgery

    NASA Astrophysics Data System (ADS)

    Speidel, S.; Kuhn, E.; Bodenstedt, S.; Röhl, S.; Kenngott, H.; Müller-Stich, B.; Dillmann, R.

    2014-03-01

    Intraoperative tracking of laparoscopic instruments is a prerequisite to realize further assistance functions. Since endoscopic images are always available, this sensor input can be used to localize the instruments without special devices or robot kinematics. In this paper, we present an image-based markerless 3D tracking of different da Vinci instruments in near real-time without an explicit model. The method is based on different visual cues to segment the instrument tip, calculates a tip point and uses a multiple object particle filter for tracking. The accuracy and robustness is evaluated with in vivo data.

  16. Leonardo da Vinci and the origin of semen

    PubMed Central

    Noble, Denis; DiFrancesco, Dario; Zancani, Diego

    2014-01-01

    It is well known that Leonardo da Vinci made several drawings of the human male anatomy. The early drawings (before 1500) were incorrect in identifying the origin of semen, where he followed accepted teaching of his time. It is widely thought that he did not correct this mistake, a view that is reflected in several biographies. In fact, he made a later drawing (after 1500) in which the description of the anatomy is remarkably accurate and must have been based on careful dissection. In addition to highlighting this fact, acknowledged previously in only one other source, this article reviews the background to Leonardo's knowledge of the relevant anatomy.

  17. Evolution of the ATLAS PanDA workload management system for exascale computational science

    NASA Astrophysics Data System (ADS)

    Maeno, T.; De, K.; Klimentov, A.; Nilsson, P.; Oleynik, D.; Panitkin, S.; Petrosyan, A.; Schovancova, J.; Vaniachine, A.; Wenaus, T.; Yu, D.; Atlas Collaboration

    2014-06-01

    An important foundation underlying the impressive success of data processing and analysis in the ATLAS experiment [1] at the LHC [2] is the Production and Distributed Analysis (PanDA) workload management system [3]. PanDA was designed specifically for ATLAS and proved to be highly successful in meeting all the distributed computing needs of the experiment. However, the core design of PanDA is not experiment specific. The PanDA workload management system is capable of meeting the needs of other data intensive scientific applications. Alpha-Magnetic Spectrometer [4], an astro-particle experiment on the International Space Station, and the Compact Muon Solenoid [5], an LHC experiment, have successfully evaluated PanDA and are pursuing its adoption. In this paper, a description of the new program of work to develop a generic version of PanDA will be given, as well as the progress in extending PanDA's capabilities to support supercomputers and clouds and to leverage intelligent networking. PanDA has demonstrated at a very large scale the value of automated dynamic brokering of diverse workloads across distributed computing resources. The next generation of PanDA will allow other data-intensive sciences and a wider exascale community employing a variety of computing platforms to benefit from ATLAS' experience and proven tools.

  18. D-A and D-2 dopamine receptor function in the rabbit retina: a model for the central nervous system

    SciTech Connect

    Hensler, J.G.

    1987-01-01

    Studies were done investigating the effect of the synaptic concentration of the transmitter DA, modified by changes in the frequency of electrical field stimulation and by the DA uptake inhibitor nomifensine, on the modulation of /sup 3/H-DA release by D-2 DA autoreceptors and by melatonin receptor sites. At lower synaptic concentrations of the transmitter dopamine, D-2 DA receptor agonists were more potent, while antagonists were more potent when the synaptic concentration of transmitter was higher. The potency of melatonin to inhibit DA release was not altered by the frequency of field stimulation of by frequency-dependent changes in the synaptic concentration of the transmitter.

  19. [Prolactin and its cleaved 16 kDa fragment].

    PubMed

    Lkhider, Mustapha; Seddiki, Touria; Ollivier-Bousquet, Michèle

    2010-12-01

    Prolactin, owing to its origins, actions and molecular forms, is an ubiquitous and pleiotropic hormone. Indeed prolactin, initially thought to be essentially synthesized in the hypophysis, is also produced by several tissues in mammals. It is involved in more than 300 different biological activities, such as reproduction, developmental immunity and behaviour. It is also described under several molecular forms resulting from co- or post-translational modifications and enzymatic cleavage. Among these, the 16 kDa form, derived from native prolactin, has received particular attention because of its inhibitory effect on angiogenesis. Recent results have suggested an important role of tissue enzymes in the production of this form in several tissues (retina, myocardium and mammary gland). The cleavage leading to the production of 16 kDa prolactin may occur outside the cells, in the interstitial medium and therefore in the vicinity of blood capillaries. This process implies tissue-specific mechanisms of regulation. A better knowledge of the location of the cleavage and of the regulation of these activities of the cleaving enzymes is now essential for controlling the processes. This knowledge will allow a better understanding of the relationships between some pathologies (cardiomyopathy, pre-eclampsia, retinopathy) and modification of the production of the anti-angiogenic form of prolactin. PMID:21187043

  20. Chandra Confirmation of a Pulsar Wind Nebula in DA 495

    NASA Technical Reports Server (NTRS)

    Arzoumanian, Z.; Safi-Harb, S.; Landecker, T.L.; Kothes, R.; Camilo, F.

    2008-01-01

    As part of a multiwavelength study of the unusual radio supernova remnant DA 495, we present observations made with the Chandra X-ray Observatory. Imaging and spectroscopic analysis confirms the previously detected X-ray source at the heart of the annular radio nebula, establishing the radiative properties of two key emission components: a soft unresolved source with a blackbody temperature of 1 MK consistent with a neutron star, surrounded by a nontherma1 nebula 40" in diameter exhibiting a power-law spectrum with photon index Gamma = 1.63, typical of a pulsar wind nebula. Morphologically, the nebula appears to be slightly extended along a direction, in projection on the sky, previously demonstrated to be of significance in radio and ASCA observations; we argue that this represents the orientation of the pulsar spin axis. At smaller scales, a narrow X-ray feature is seen extending out 5" from the point source, but energetic arguments suggest that it is not the resolved termination shock of the pulsar wind against the ambient medium. Finally, we argue based on synchrotron lifetimes in the nebular magnetic field that DA 495 represents the first example of a pulsar wind nebula in which electromagnetic flux makes up a significant part, together with particle flux, of the neutron star's wind.

  1. 28 kDa adenosine-binding proteins of brain and other tissues.

    PubMed Central

    Ravid, K; Rosenthal, R A; Doctrow, S R; Lowenstein, J M

    1989-01-01

    Membranes prepared from calf brain were solubilized and chromatographed on a column containing 5'-amino-5'-deoxyadenosine covalently linked to agarose through the 5'-amino group. When the column was eluted with adenosine, a pure protein emerged with subunit molecular mass of 28 kDa. The protein was extracted from the membranes with sodium cholate, but not with 100 microM-adenosine or 0.5 M-NaCl. A similar 28 kDa protein was isolated from the soluble fraction of calf brain. The yield of membrane-bound and soluble 28 kDa protein per gram of tissue was about the same. The 28 kDa protein was also found in membrane and soluble fractions of rabbit heart, rat liver and vascular smooth muscle from calf aorta. The yield per gram of tissue fell into the order brain greater than heart approximately vascular smooth muscle greater than liver for the 28 kDa protein from the membrane fraction, and brain approximately heart greater than vascular smooth muscle greater than liver for the 28 kDa protein from the soluble fraction. Polyclonal antibodies to pure 28 kDa protein from calf brain membranes cross-reacted with the 28 kDa protein from calf brain soluble fraction and with 28 kDa proteins isolated from other tissues. The 28 kDa protein from calf brain membranes was also eluted from the affinity column by AMP and 2',5'-dideoxyadenosine, but at a concentration higher than that at which adenosine eluted the protein, but N6-(R-phenylisopropyl)adenosine, 5'-N-ethylcarboxamidoadenosine, ADP, ATP, GTP, NAD+, cyclic AMP and inosine failed to elute the protein at concentrations up to 1 mM. The 28 kDa protein from the soluble fraction was not eluted by 3 mM-AMP or 1 mM-N6-(R-phenylisopropyl)adenosine,-5'-N-ethylcarboxamidoadenosine or -cyclic AMP. Unexpectedly, the soluble 28 kDa protein was eluted by AMP in the presence of sodium cholate. Soluble 28 kDa protein from calf brain had a KD for adenosine of 12 microM. Membrane 28 kDa protein from calf brain had a KD of 14 microM in the presence of 0.1% sodium cholate. Amino acid compositions of the 28 kDa proteins were similar, but not identical. Images Fig. 1. Fig. 2. Fig. 4. PMID:2730563

  2. Immunoreactivity of the Mycobacterium avium subsp. paratuberculosis 19-kDa lipoprotein

    PubMed Central

    Huntley, Jason FJ; Stabel, Judith R; Bannantine, John P

    2005-01-01

    Background The Mycobacterium tuberculosis 19-kDa lipoprotein has been reported to stimulate both T and B cell responses as well as induce a number of Th1 cytokines. In order to evaluate the Mycobacterium avium subsp. paratuberculosis (M. avium subsp. paratuberculosis) 19-kDa lipoprotein as an immunomodulator in cattle with Johne's disease, the gene encoding the 19-kDa protein (MAP0261c) was analyzed. Results MAP0261c is conserved in mycobacteria, showing a 95% amino acid identity in M. avium subspecies avium, 84% in M. intracellulare and 76% in M. bovis and M. tuberculosis. MAP0261c was cloned, expressed, and purified as a fusion protein with the maltose-binding protein (MBP-19 kDa) in Escherichia coli. IFN-? production was measured from 21 naturally infected and 9 control cattle after peripheral blood mononuclear cells (PBMCs) were stimulated with a whole cell lysate (WCL) of M. avium subsp. paratuberculosis or the recombinant MBP-19 kDa. Overall, the mean response to MBP-19 kDa was not as strong as the mean response to the WCL. By comparison, cells from control, non-infected cattle did not produce IFN-? after stimulation with either WCL or MBP-19 kDa. To assess the humoral immune response to the 19-kDa protein, sera from cattle with clinical Johne's disease were used in immunoblot analysis. Reactivity to MBP-19 kDa protein, but not MBP alone, was observed in 9 of 14 infected cattle. Antibodies to the 19-kDa protein were not observed in 8 of 9 control cows. Conclusions Collectively, these results demonstrate that while the 19-kDa protein from M. avium subsp. paratuberculosis stimulates a humoral immune response and weak IFN-? production in infected cattle, the elicited responses are not strong enough to be used in a sensitive diagnostic assay. PMID:15663791

  3. COMO SE CONECTAR A REDE WIFI DA BIBLIOTECA Para conectar a rede WIFI da biblioteca a partir do notebook, siga os passos abaixo

    E-print Network

    Paraná, Universidade Federal do

    1 COMO SE CONECTAR A REDE WIFI DA BIBLIOTECA Para conectar a rede WIFI da biblioteca a partir do. Se caso apareça mais opções procure pela "Conectar-se a internet". 3º Passo: - Ao clicar em "Conectar-se as conexões disponíveis para você se conectar: 5º Passo: Ao serem procuradas e exibidas as conexões

  4. Stress and Failure Analysis of Rapidly Rotating Asteroid (29075) 1950 DA

    NASA Astrophysics Data System (ADS)

    Hirabayashi, M.; Scheeres, D. J.

    2015-01-01

    Rozitis et al. reported that 1950 DA is a rubble pile and requires a cohesive strength of at least 44 Pa to 74 Pa to keep the current shape. This paper develops a finite element model and revisits the analysis of the failure condition of 1950 DA.

  5. Processing and Visualizing Planetary Data Using DaVinci: Updates for Portability and Scriptable Execution

    NASA Astrophysics Data System (ADS)

    Edwards, C. S.; Anwar, S.; Hagee, W.; Doerres, D.; Dickensheid, S.; Christensen, P. R.

    2015-06-01

    We present updates to the DaVinci software toolkit that enable stand-alone reading of ISIS3 files, a link between DaVinci and JMARS, the ingestion and use of geospatial information, and a series of executable THEMIS processing scripts.

  6. Was machen die da druben in der Numerik? Die Verbindung zur Topologie

    E-print Network

    Löh, Clara

    Was machen die da dr¨uben in der Numerik? Die Verbindung zur Topologie Verallgemeinerung in n-Dimensionen Anwendungsbeispiel Segmentierung Einf¨uhrung in die algorithmische Topologie Michael Moeller April 14, 2010 Michael Moeller Einf¨uhrung in die algorithmische Topologie #12;Was machen die da dr¨uben in der Numerik? Die

  7. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Standards for nitrogen oxides (NOX). 60.44Da Section 60.44Da Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Electric Utility Steam Generating Units §...

  8. 76 FR 55293 - Special Conditions: Diamond Aircraft Industries, Model DA-40NG; Electronic Engine Control (EEC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ...23-10-03-SC] Special Conditions: Diamond Aircraft Industries, Model DA-40NG...notice proposes special conditions for the Diamond Aircraft Industries (DAI), model DA-40NG...commenter. Background On May 11, 2010 Diamond Aircraft Industry GmbH applied for...

  9. 32 CFR Appendix F to Part 623 - Power of Attorney (DA Form 4881-4-R)

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Power of Attorney (DA Form 4881-4-R) F Appendix F to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. F Appendix F to Part 623—Power of Attorney (DA Form...

  10. 32 CFR Appendix F to Part 623 - Power of Attorney (DA Form 4881-4-R)

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Power of Attorney (DA Form 4881-4-R) F Appendix F to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. F Appendix F to Part 623—Power of Attorney (DA Form...

  11. 32 CFR Appendix F to Part 623 - Power of Attorney (DA Form 4881-4-R)

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Power of Attorney (DA Form 4881-4-R) F Appendix F to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. F Appendix F to Part 623—Power of Attorney (DA Form...

  12. Evolution of the ATLAS PanDA Workload Management System for Exascale Computational Science

    E-print Network

    Maeno, T; The ATLAS collaboration; Klimentov, A; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Schovancova, J; Vaniachine, A; Wenaus, T; Yu, D

    2013-01-01

    An important foundation underlying the impressive success of data processing and analysis in the ATLAS experiment [1] at the LHC [2] is the Production and Distributed Analysis (PanDA) workload management system [3]. PanDA was designed specifically for ATLAS and proved to be highly successful in meeting all the distributed computing needs of the experiment. However, the core design of PanDA is not experiment specific. The PanDA workload management system is capable of meeting the needs of other data intensive scientific applications. Alpha-Magnetic Spectrometer [4], an astro-particle experiment on the International Space Station, and the Compact Muon Solenoid [5], an LHC experiment, have successfully evaluated PanDA and are pursuing its adoption. In this paper, a description of the new program of work to develop a generic version of PanDA will be given, as well as the progress in extending PanDA's capabilities to support supercomputers and clouds and to leverage intelligent networking. PanDA has demonstrated a...

  13. 76 FR 19903 - Special Conditions: Diamond Aircraft Industry Model DA-40NG; Diesel Cycle Engine

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ...Diamond Aircraft Industry Model DA-40NG; Diesel Cycle Engine...Aircraft Industry (DAI) GmbH model DA-40NG the Austro Engine...as applicable to various models); 23.572; 23.573; 23...Tests or analysis, or a combination of methods, must show...

  14. 17 CFR 209.1 - Form D-A: Disclosure of assets and financial information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...2010-04-01 false Form D-A: Disclosure of assets and financial information. 209.1 Section 209.1 Commodity...PRACTICE § 209.1 Form D-A: Disclosure of assets and financial information. (a) Rules 410 and 630...

  15. 40 CFR 60.40Da - Applicability and designation of affected facility.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Applicability and designation of affected facility. 60.40Da Section 60.40Da Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Standards of Performance for Electric Utility Steam...

  16. A Creative Approach to the Common Core Standards: The Da Vinci Curriculum

    ERIC Educational Resources Information Center

    Chaucer, Harry

    2012-01-01

    "A Creative Approach to the Common Core Standards: The Da Vinci Curriculum" challenges educators to design programs that boldly embrace the Common Core State Standards by imaginatively drawing from the genius of great men and women such as Leonardo da Vinci. A central figure in the High Renaissance, Leonardo made extraordinary contributions as a…

  17. R. Zingales -L'atomismo chimico L'atomismo chimico, da Dalton a Cannizzaro

    E-print Network

    Spagnolo, Filippo

    alchimisti in una scienza moderna, Antoine Laurent Lavoisier (1743-1794), per l'enfasi che diede sempre alla sia da Pierre Joseph Macquer (1718-1784), nel Dizionario di Chimica (2a ed, 1777), che da Antoine, coniugata a una geniale capa- cità di analisi e sintesi concettuale, Lavoisier si pose l'obiettivo di

  18. Distance-Adaptive Routing and Spectrum Assignment (DA-RSA) in Rings

    E-print Network

    with traffic grooming was considered in [11]. The joint routing, spectrum assignment, and modulation formatDistance-Adaptive Routing and Spectrum Assignment (DA-RSA) in Rings Sahar Talebi, Iyad Katib that the the distance- adaptive routing and spectrum assignment (DA-RSA) problem in mesh networks is a special case

  19. EXAM SCORE MNOA CREDIT ART HISTORY 3 3 credits for ART DA

    E-print Network

    Reed, Nancy E.

    EXAM SCORE MNOA CREDIT ART HISTORY 3 3 credits for ART DA 4 - 5 3 credits for ART 101 ART STUDIO 3 - 5 3 credits for ART DA (ART DRAWING, 2-D DESIGN, 3-D DESIGN) CALCULUS AB 3 No credits: Students can enroll in MATH 203, 215, or 241 AFTER obtaining approval from the Math Department. 4 - 5 4 credits

  20. 32 CFR Appendix F to Part 623 - Power of Attorney (DA Form 4881-4-R)

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Power of Attorney (DA Form 4881-4-R) F Appendix F to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. F Appendix F to Part 623—Power of Attorney (DA Form...

  1. 32 CFR Appendix F to Part 623 - Power of Attorney (DA Form 4881-4-R)

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Power of Attorney (DA Form 4881-4-R) F Appendix F to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. F Appendix F to Part 623—Power of Attorney (DA Form...

  2. Estudo revela que dunas da cratera de Gale em Marte esto ativas Autor: Catarina Solano

    E-print Network

    Instituto de Sistemas e Robotica

    Estudo revela que dunas da cratera de Gale em Marte estão ativas Autor: Catarina Solano Data de liderada pelo instituto norte-americano SETI concluiu que as dunas da cratera de Gale, no planeta Marte transporte de sedimentos em Marte", sublinha David Vaz, que também é investigador no Centro de Recursos

  3. Solution NMR Structure of the 48-kDa IIAMannose -HPr Complex of

    E-print Network

    Clore, G. Marius

    Solution NMR Structure of the 48-kDa IIAMannose -HPr Complex of the Escherichia coli Mannose structure of the 48-kDa IIAMan -HPr com- plex of the mannose branch of the Escherichia coli phos sugar- specific enzymes II, which fall into four major families (glucose, mannitol, mannose, and lactose

  4. REGULAMENTO DOS ESTGIOS SUPERVISIONADOS DO CURSO DE PSICOLOGIA DA UNIVERSIDADE FEDERAL DO PARAN

    E-print Network

    Paraná, Universidade Federal do

    1 REGULAMENTO DOS ESTÁGIOS SUPERVISIONADOS DO CURSO DE PSICOLOGIA DA UNIVERSIDADE FEDERAL DO PARANÁ-obrigatórios do curso de Psicologia estão regulamentados em legislação federal pela Lei n°. 6494/77, pelo Decreto estágios do curso de Psicologia da UFPR estão regulamentados internamente pela Resolução n°.19/90-CEPE

  5. Pa?u Ayurv?da (veterinary medicine) in Garudapur??a.

    PubMed

    Varanasi, Subhose; Narayana, A

    2007-01-01

    The history of veterinary medicine is closely tied to the development of human medicine. Evidence of animal medicine has been found in ancient civilizations, such as those of the Hindu, Babylonians, Hebrews, Arabs, Greeks, and Romans. Ancient Indian literature in the form of the holy V?da, Pur?na, Br?hma?a, epics, etc. is flooded with information on animal care. The Pur??a are ancient scriptures discuss varied topics like devotion to God and his various aspects, traditional sciences like Ayurv?da, Jy?ti?a (Astrology), cosmology, concepts like dharma, karma, reincarnation and many others. The treatment of animal diseases using Ayurvedic medicine has been mentioned in Garudapur?na, Agnipur??a, Atri-samhit?, Matsyapur??a and many other texts. The Garudapur??a is one of the important S?ttvika pur?na, the subject matter is divided into two parts, viz. P?rvakha?da (first part) and an Uttarakha?da (subsequent part). Gav?yurv?da, Gaj?yurv?da narrated briefly and A?v?yurv?da described detailly in P?rvakha?da. PMID:19580108

  6. Avaliao de Mtodos de Interpolao do Sinal de Variabilidade da Freqncia Cardaca

    E-print Network

    Carvalho, João Luiz

    métodos de interpolação do sinal de variabilidade da freqüência cardíaca, ou heart rate variability (HRV). O sinal de HRV é usado como uma ferramenta para a avaliação da atuação do sistema nervoso para a análise espectral do sinal de HRV, mas estes exigem que o sinal tenha sido amostrado com taxa de

  7. 32 CFR Appendix E to Part 623 - Surety Bond (DA Form 4881-3-R)

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Surety Bond (DA Form 4881-3-R) E Appendix E to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. E Appendix E to Part 623—Surety Bond (DA Form...

  8. 32 CFR Appendix E to Part 623 - Surety Bond (DA Form 4881-3-R)

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Surety Bond (DA Form 4881-3-R) E Appendix E to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. E Appendix E to Part 623—Surety Bond (DA Form...

  9. 32 CFR Appendix E to Part 623 - Surety Bond (DA Form 4881-3-R)

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Surety Bond (DA Form 4881-3-R) E Appendix E to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. E Appendix E to Part 623—Surety Bond (DA Form...

  10. 32 CFR Appendix E to Part 623 - Surety Bond (DA Form 4881-3-R)

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Surety Bond (DA Form 4881-3-R) E Appendix E to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. E Appendix E to Part 623—Surety Bond (DA Form...

  11. A Value-Engaged Approach for Evaluating the Bunche-Da Vinci Learning Academy

    ERIC Educational Resources Information Center

    Greene, Jennifer C.

    2005-01-01

    In 2001, the Bunche Academy was chosen by its district to join in partnership with the Da Vinci Learning Corporation to embark on an ambitious whole-school reform initiative, especially designed by the corporation for low-performing schools. In this chapter, the author describes how, as illustrated in the Bunche-Da Vinci Learning Academy context,…

  12. The Indicative and Subjunctive "da"-complements in Serbian A Syntactic-Semantic Approach

    ERIC Educational Resources Information Center

    Todorovic, Natasa

    2012-01-01

    A syntactic-semantic investigation of subjunctive and indicative "da"-complements in Serbian is conducted in this project. After a careful comparison of Serbian sentence constructions with "da"-complements to the equivalent sentence structures in languages of the Balkans as well as other Slavic languages, it is clearly…

  13. Energy Consumption Tools Pack Leandro Fontoura Cupertino, Georges DaCosta,

    E-print Network

    Lefèvre, Laurent

    Energy Consumption Tools Pack Leandro Fontoura Cupertino, Georges DaCosta, Amal Sayah, Jean) GreenDays @ Luxembourg ­ January 28-29th 2013 Cupertino, DaCosta, Sayah, Pierson (IRIT) Energy Consumption Tools Pack 1 / 23 #12;Outline 1 Introduction Motivation Our proposal 2 Energy Consumption Tools

  14. A Proposal to Build Evaluation Capacity at the Bunche-Da Vinci Learning Partnership Academy

    ERIC Educational Resources Information Center

    King, Jean A.

    2005-01-01

    The author describes potential evaluation capacity-building activities in contrast to the specifics of an evaluation design. Her response to the case of the Bunche-Da Vinci Learning Partnership Academy is developed in three parts: (1) an initial framing of the Bunche-Da Vinci situation; (2) what should be done before signing a contract; and (3)…

  15. Relatrio de Atividades de 2002 da Linha de Pesquisa e Desenvolvimento em Fuso Termonuclear Controlada FUSO

    E-print Network

    de alta potência. O pessoal da equipe de apoio técnico teve, em sua maior parte, dedicação em tempo pesquisa, Teoria e Engenharia) Dr. Edson Del Bosco (Operação da máquina, Diagnósticos, Chefe do LAP ­ Tempo parcial) Dr. Joaquim José Barroso de Castro (Fontes de microondas ­ Tempo parcial) Dr. Luiz Ângelo Berni

  16. 32 CFR 516.14 - Service of process on DA or Secretary of Army.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Service of process on DA or Secretary of Army. 516.14 Section 516.14 National...Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS...Service of process on DA or Secretary of Army. The Chief, Litigation...

  17. 32 CFR 516.14 - Service of process on DA or Secretary of Army.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Service of process on DA or Secretary of Army. 516.14 Section 516.14 National...Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS...Service of process on DA or Secretary of Army. The Chief, Litigation...

  18. 32 CFR 516.14 - Service of process on DA or Secretary of Army.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Service of process on DA or Secretary of Army. 516.14 Section 516.14 National...Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS...Service of process on DA or Secretary of Army. The Chief, Litigation...

  19. 32 CFR 516.14 - Service of process on DA or Secretary of Army.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Service of process on DA or Secretary of Army. 516.14 Section 516.14 National...Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS...Service of process on DA or Secretary of Army. The Chief, Litigation...

  20. DA 2 Merging Operators # S. Konieczny a J. Lang a P. Marquis b

    E-print Network

    Lang, Jérôme

    DA 2 Merging Operators # S. Konieczny a J. Lang a P. Marquis b a IRIT ­ CNRS / Universitâ??e Paul A new framework for propositional merging is presented. DA 2 merging operators, parameterized and aggregation functions can be used and many merging operators already defined in the literature (including both

  1. 32 CFR Appendix E to Part 623 - Surety Bond (DA Form 4881-3-R)

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Surety Bond (DA Form 4881-3-R) E Appendix E to Part 623 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY SUPPLIES AND EQUIPMENT LOAN OF ARMY MATERIEL Pt. 623, App. E Appendix E to Part 623—Surety Bond (DA Form...

  2. ARTIGO INTERNET Programa da troika "tem de ir evoluindo ao longo do tempo", diz Fernando

    E-print Network

    Instituto de Sistemas e Robotica

    ARTIGO INTERNET Programa da troika "tem de ir evoluindo ao longo do tempo", diz Fernando Ulrich ir evoluindo ao longo do tempo", diz Fernando Ulrich O presidente do BPI, Fernando Ulrich, considerou tempo" e que os justos não podem pagar pelos pecadores a nível de cortes. Falando à margem da

  3. Evidence for a 12?kDa “Carrier Protein” for Natriuretic Hormone

    PubMed Central

    Gonick, Harvey C.

    2014-01-01

    The search for the elusive Na-K-ATPase-inhibiting natriuretic hormone continues. In this review, evidence is presented that isolating the carrier protein for natriuretic hormone from hypertensive plasma is a necessary first step before splitting off the final hormone. The carrier protein has a molecular weight of 12?kDa while the final hormone has a molecular weight of 408?Da. Both compounds inhibit Na-K-ATPase but the compound containing the carrier protein predominates. The question has been raised as to whether the carrier protein is in actuality proANF, a 17?kDa protein that can be split between a 14?kDa protein (the presumptive proANF) and the 3?kDa ANF. PMID:25477863

  4. PanDA Beyond ATLAS: Workload Management for Data Intensive Science

    E-print Network

    Schovancova, J; The ATLAS collaboration; Klimentov, A; Maeno, T; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Vaniachine, A; Wenaus, T; Yu, D

    2013-01-01

    The PanDA Production ANd Distributed Analysis system has been developed by ATLAS to meet the experiment's requirements for a data-driven workload management system for production and distributed analysis processing capable of operating at LHC data processing scale. After 7 years of impressively successful PanDA operation in ATLAS there are also other experiments which can benefit from PanDA in the Big Data challenge, with several at various stages of evaluation and adoption. The new project "Next Generation Workload Management and Analysis System for Big Data" is extending PanDA to meet the needs of other data intensive scientific applications in HEP, astro-particle and astrophysics communities, bio-informatics and other fields as a general solution to large scale workload management. PanDA can utilize dedicated or opportunistic computing resources such as grids, clouds, and High Performance Computing facilities, and is being extended to leverage next generation intelligent networks in automated workflow mana...

  5. 40 CFR 60.45Da - Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 false Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO). 60.45Da Section...Generating Units § 60.45Da Alternative standards for combined nitrogen oxides (NOX ) and carbon monoxide (CO). (a)...

  6. 40 CFR 60.45Da - Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO). 60.45Da Section...Generating Units § 60.45Da Alternative standards for combined nitrogen oxides (NOX ) and carbon monoxide (CO). (a)...

  7. 40 CFR 60.45Da - Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 false Alternative standards for combined nitrogen oxides (NOX) and carbon monoxide (CO). 60.45Da Section...Generating Units § 60.45Da Alternative standards for combined nitrogen oxides (NOX ) and carbon monoxide (CO). (a)...

  8. Absolutely Continuous Invariant Measures for a Class of Affine Interval Exchange Zaqueu Coelho; Artur Lopes; Luiz Fernando da Rocha

    E-print Network

    Lopes, Artur Oscar

    ; Artur Lopes; Luiz Fernando da Rocha Proceedings of the American Mathematical Society, Vol. 123, No. 11 INTERVAL EXCHANGE MAPS ZAQUEU COELHO, ARTUR LOPES, AND LUIZ FERNANDO DA ROCHA (Communicated by Linda Keen

  9. Da Vinci facility is state-of-the art.

    PubMed

    Baillie, Jonathan

    2011-10-01

    Growing demand for a wide range of surgical procedures, coupled with a strong belief in the advantages--both to surgeons and patients--of minimally invasive robot-assisted surgery, have seen the Royal Wolverhampton Hospitals NHS Trust open a new twin operating theatre suite, equipped with the Midlands' first da Vinci surgical robot, at Wolverhampton's New Cross Hospital. The two theatres, together with accompanying "preparation" and scrub facilities, and a separate five-bed recovery bay to serve several of the hospital's eight other existing main theatres, were completed to time and on budget recently by modular construction specialist, MTX Contracts, under a pound 2 million design and build contract, as HEJ editor Jonathan Baillie reports. PMID:22053358

  10. VLBI Radar of the 2012 DA14 Asteroid

    NASA Astrophysics Data System (ADS)

    Nechaeva, M. B.; Dugin, N. A.; Antipenko, A. A.; Bezrukov, D. A.; Bezrukov, V. V.; Voytyuk, V. V.; Dement'ev, A. F.; Jekabsons, N.; Klapers, M.; Konovalenko, A. A.; Kulishenko, V. F.; Nabatov, A. S.; Nesteruk, V. N.; Putillo, D.; Reznichenko, A. M.; Salerno, E.; Snegirev, S. D.; Tikhomirov, Yu. V.; Khutornoy, R. V.; Skirmante, K.; Shmeld, I.; Chagunin, A. K.

    2015-03-01

    An experiment on VLBI radar of the 2012 DA14 asteroid was carried out on February 15-16, 2011 at the time of its closest approach to the Earth. The research teams of Kharkov (Institute of Radio Astronomy of the National Academy of Sciences of Ukraine), Evpatoria (National Space Facilities Control and Test Center), Nizhny Novgorod (Radiophysical Research Institute), Bologna (Istituto di Radioastronomia (INAF)), and Ventspils (Ventspils International Radioastronomy Center) took part in the experiment. The asteroid was irradiated by the RT-70 planetary radar (Evpatoria) at a frequency of 5 GHz. The reflected signal was received using two 32-m radio telescopes in Medicina (Italy) and Irbene (Latvia) in radiointerferometric mode. The Doppler frequency shifts in bi-static radar mode and interference frequency in VLBI mode were measured. Accuracy of the VLBI radar method for determining the radial and angular velocities of the asteroid were estimated.

  11. Chandra Confirmation of a Pulsar Wind Nebula in DA 495

    E-print Network

    Z. Arzoumanian; S. Safi-Harb; T. L. Landecker; R. Kothes; F. Camilo

    2008-06-23

    As part of a multiwavelength study of the unusual radio supernova remnant DA 495, we present observations made with the Chandra X-ray Observatory. Imaging and spectroscopic analysis confirms the previously detected X-ray source at the heart of the annular radio nebula, establishing the radiative properties of two key emission components: a soft unresolved source with a blackbody temperature of 1 MK consistent with a neutron star, surrounded by a nonthermal nebula 40'' in diameter exhibiting a power-law spectrum with photon index Gamma = 1.6+/-0.3, typical of a pulsar wind nebula. The implied spin-down luminosity of the neutron star, assuming a conversion efficiency to nebular flux appropriate to Vela-like pulsars, is ~10^{35} ergs/s, again typical of objects a few tens of kyr old. Morphologically, the nebular flux is slightly enhanced along a direction, in projection on the sky, independently demonstrated to be of significance in radio polarization observations; we argue that this represents the orientation of the pulsar spin axis. At smaller scales, a narrow X-ray feature is seen extending out 5'' from the point source, a distance consistent with the sizes of resolved wind termination shocks around many Vela-like pulsars. Finally, we argue based on synchrotron lifetimes in the estimated nebular magnetic field that DA 495 represents a rare pulsar wind nebula in which electromagnetic flux makes up a significant part, together with particle flux, of the neutron star's wind, and that this high magnetization factor may account for the nebula's low luminosity.

  12. DaVinci-assisted laparoscopic radical prostatectomy: the learning curve

    NASA Astrophysics Data System (ADS)

    Le, Carter Q.; Ho, Khai-Linh V.; Gettman, Matthew T.

    2007-02-01

    Objective: To define the learning curve for daVinci-assisted laparoscopic radical prostatectomy (DLP) at our institution. Methods: The data from 170 patients who underwent DLP between August 2002 and December 2004 by a single surgeon (MTG) were reviewed. Operative time, hemoglobin decrease, conversion to open procedure, positive margin rates, complications, length of stay (LOS), length of catheterization, continence, and erectile function were analyzed. Results: Hemoglobin decrease (p=0.11), positive margin rates (p=0.80), and early urinary continence (p=0.17) did not significantly correlate with surgical experience. A trend towards lower complications (p=0.07) and an earlier return of erectile function (p=0.09) was noted with increased experience with DLP. Operative time, hospital stay, catheterization time, and open conversion showed significant association with patient sequence. Median operative time for the first 60 and the last 110 patients was 323.5 and 239.5 minutes (p=<0.0001), respectively. Median LOS for the aforementioned groups was 53 and 51 hours (p=0.009). Length of catheterization declined significantly between the first 60 and the remaining 110 patients, 14 as compared to 11.5 days (p=<0.0001). Eight open conversions occurred, six were in the first 30 patients (p=0.03). Conclusion: As an indicator of the learning curve, the operative time in our series showed no correlation with sequence after the 60 th patient. Thus, despite the advantages of robotics, the learning curve to efficient performance of daVinciassisted laparoscopic radical prostatectomy is long. Oncological and functional outcomes should not be affected during the learning curve.

  13. 11 CFR 111.14 - Witness fees and mileage (2 U.S.C. 437d(a)(5)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...false Witness fees and mileage (2 U.S.C. 437d(a)(5)). 111.14 Section...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111.14 Witness fees and mileage (2 U.S.C. 437d(a)(5)). Witnesses...

  14. 11 CFR 111.11 - Written questions under order (2 U.S.C. 437d(a)(1)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...Written questions under order (2 U.S.C. 437d(a)(1)). 111.11 Section...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...Written questions under order (2 U.S.C. 437d(a)(1)). The...

  15. 11 CFR 111.11 - Written questions under order (2 U.S.C. 437d(a)(1)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...Written questions under order (2 U.S.C. 437d(a)(1)). 111.11 Section...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...Written questions under order (2 U.S.C. 437d(a)(1)). The...

  16. 11 CFR 111.14 - Witness fees and mileage (2 U.S.C. 437d(a)(5)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...true Witness fees and mileage (2 U.S.C. 437d(a)(5)). 111.14 Section...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111.14 Witness fees and mileage (2 U.S.C. 437d(a)(5)). Witnesses...

  17. Pgina Inicial Empresas Startup de Cantanhede no top mundial da sade Na edio deste sbado do Dinheiro

    E-print Network

    Instituto de Sistemas e Robotica

    Dinheiro Vivo (vendido com o DN e com o JN), e que também poderá... LEIA TUDO Últimas Telecom Construção:00 | Dinheiro Vivo Uma das dez melhores startups da área da saúde a nível mundial é portuguesa: a Heart | REGISTAR Pesquisa SITES DO GRUPO Startup de Cantanhede no top mundial da saúde - Dinheiro Vivo http

  18. Tão perto de casa, tão longe de nós: etnografia das novas margens no centro da urbe

    PubMed Central

    Fernandes, Por Luís

    2011-01-01

    Philippe Bourgois é, desde 2007, “Richard Perry University professor” no Departamento de Antropologia e de Medicina Familiar e de Práticas Comunitárias na Universidade da Pensilvânia. Esteve durante largos anos ligado ao Departamento de Antropologia, História e Medicina Social da Universidade da Califórnia, São Francisco. A publicação, em 1995, de In Search of Respect: Selling Crack in El Barrio1 projectaria o seu nome muito para além dos Estados Unidos: uma etnografia no coração porto-riquenho do Harlem, em torno dos actores e dos ambientes da venda de crack. Seguir-se-ia um longo trabalho de terreno em acampamentos de dependentes de heroína em São Francisco, orientando o seu trabalho para as formas mais radicais da pobreza e da marginalidade nos EUA. É deste trabalho de terreno que sai o seu último livro, Righteous Dopefiend2. Em Junho de 2007 esteve em Lisboa para participar na 3.a edição do “Ethnografeast”. Foi então que aproveitámos a oportunidade para ouvir um percurso invulgar contado pelo próprio: uma longa conversa no Hotel Zurique, cujo nome só vem ao caso por evocar o país onde passou uma parte da infância. PMID:22013286

  19. Endogenous dopamine (DA) modulates (3H)spiperone binding in vivo in rat brain

    SciTech Connect

    Bischoff, S.; Krauss, J.; Grunenwald, C.; Gunst, F.; Heinrich, M.; Schaub, M.; Stoecklin, K.V.; Vassout, A.; Waldmeier, P.; Maitre, L. )

    1991-01-01

    (3H)spiperone (SPI) binding in vivo, biochemical parameters and behavior were measured after modulating DA levels by various drug treatments. DA releasers and uptake inhibitors increased SPI binding in rat striatum. In other brain areas, the effects were variable, but only the pituitary remained unaffected. Surprisingly, nomifensine decreased SPI binding in frontal cortex. The effects of these drugs were monitored by measuring DA, serotonin (5-HT) and their metabolites in the same rats. The increased SPI binding in striatum was parallel to the locomotor stimulation with the following rank order: amfonelic acid greater than nomifensine greater than D-amphetamine greater than or equal to methylphenidate greater than amineptine greater than bupropion. Decreasing DA levels with reserpine or alpha-methyl-para-tyrosine reduced SPI binding by 45% in striatum only when both drugs were combined. In contrast, reserpine enhanced SPI binding in pituitary. Thus, the amount of releasable DA seems to modulate SPI binding characteristics. It is suggested that in vivo, DA receptors are submitted to dynamic regulation in response to changes in intrasynaptic concentrations of DA.

  20. Biofortification of soybean meal: immunological properties of the 27 kDa ?-zein.

    PubMed

    Krishnan, Hari B; Jang, Sungchan; Kim, Won-Seok; Kerley, Monty S; Oliver, Melvin J; Trick, Harold N

    2011-02-23

    Legumes, including soybeans ( Glycine max ), are deficient in sulfur-containing amino acids, which are required for the optimal growth of monogastric animals. This deficiency can be overcome by expressing heterologous proteins rich in sulfur-containing amino acids in soybean seeds. A maize 27 kDa ?-zein, a cysteine-rich protein, has been successfully expressed in several crops including soybean, barley, and alfalfa with the intent to biofortify these crops for animal feed. Previous work has shown that the maize 27 kDa zein can withstand digestion by pepsin and elicit an immunogenic response in young pigs. By use of sera from patients who tested positive by ImmunoCAP assay for elevated IgE to maize proteins, specific IgE binding to the 27 kDa ?-zein is demonstrated. Bioinformatic analysis using the full-length and 80 amino acid sliding window FASTA searches identified significant sequence homology of the 27 kDa ?-zein with several known allergens. Immunoblot analysis using human serum that cross-reacts with maize seed proteins also revealed specific IgE-binding to the 27 kDa ?-zein in soybean seed protein extracts containing the 27 kDa zein. This study demonstrates for the first time the allergenicity potential of the 27 kDa ?-zein and the potential that this protein has to limit livestock performance when used in soybeans that serve as a biofortified feed supplement. PMID:21226519

  1. Porphyromonas gulae 41-kDa fimbriae induced osteoclast differentiation and cytokine production

    PubMed Central

    SASAKI, Haruka; WATANABE, Kiyoko; TOYAMA, Toshizo; KOYATA, Yasunori; HAMADA, Nobushiro

    2014-01-01

    Porphyromonas gulae is considered to be associated with canine periodontitis. We have previously reported that the P. gulae American Type Culture Collection (ATCC) 51700 comprised 41-kDa fimbriae. The purpose of the present study was to demonstrate the roles of 41-kDa fimbrial protein in periodontal disease. In this study, we examined the involvement of the 41-kDa fimbrial protein in osteoclast differentiation and cytokine production in murine macrophages. Furthermore, alveolar bone resorption induced by P. gulae infection in rats was evaluated. To estimate osteoclast differentiation, bone marrow cells and MC3T3-G2/PA6 cells were cultured with or without the 41-kDa fimbrial protein for 7 days. BALB/c mouse peritoneal macrophages were stimulated with the 41-kDa fimbrial protein, and the levels of interleukin (IL)-1? and tumor necrosis factor (TNF)-? production were determined by enzyme-linked immunosorbent assay. Osteoclast differentiation was significantly enhanced by treatment with the 41-kDa fimbrial protein in a dose-dependent manner. The total area of pits formed on the dentine slices with osteoclasts incubated with the 41-kDa fimbrial protein was significantly greater than that of the control. The purified 41-kDa fimbrial protein induced IL-1? and TNF-? production in BALB/c mouse peritoneal macrophages after 6 hr of incubation in a dose-dependent manner. The bone loss level in rats infected with P. gulae was significantly higher than that of the sham-infected rats. These results suggest that P. gulae 41-kDa fimbriae play important roles in the pathogenesis of periodontal disease. PMID:25421499

  2. Porphyromonas gulae 41-kDa fimbriae induced osteoclast differentiation and cytokine production.

    PubMed

    Sasaki, Haruka; Watanabe, Kiyoko; Toyama, Toshizo; Koyata, Yasunori; Hamada, Nobushiro

    2015-03-01

    Porphyromonas gulae is considered to be associated with canine periodontitis. We have previously reported that the P. gulae American Type Culture Collection (ATCC) 51700 comprised 41-kDa fimbriae. The purpose of the present study was to demonstrate the roles of 41-kDa fimbrial protein in periodontal disease. In this study, we examined the involvement of the 41-kDa fimbrial protein in osteoclast differentiation and cytokine production in murine macrophages. Furthermore, alveolar bone resorption induced by P. gulae infection in rats was evaluated. To estimate osteoclast differentiation, bone marrow cells and MC3T3-G2/PA6 cells were cultured with or without the 41-kDa fimbrial protein for 7 days. BALB/c mouse peritoneal macrophages were stimulated with the 41-kDa fimbrial protein, and the levels of interleukin (IL)-1? and tumor necrosis factor (TNF)-? production were determined by enzyme-linked immunosorbent assay. Osteoclast differentiation was significantly enhanced by treatment with the 41-kDa fimbrial protein in a dose-dependent manner. The total area of pits formed on the dentine slices with osteoclasts incubated with the 41-kDa fimbrial protein was significantly greater than that of the control. The purified 41-kDa fimbrial protein induced IL-1? and TNF-? production in BALB/c mouse peritoneal macrophages after 6 hr of incubation in a dose-dependent manner. The bone loss level in rats infected with P. gulae was significantly higher than that of the sham-infected rats. These results suggest that P. gulae 41-kDa fimbriae play important roles in the pathogenesis of periodontal disease. PMID:25421499

  3. Stability of new carbapenem DA-1131 to renal dipeptidase (dehydropeptidase I).

    PubMed

    Park, Sung Wook; We, Jeoung Soon; Kim, Gye Won; Choi, Seong Hak; Park, Haeng Soon

    2002-02-01

    The stability of DA-1131 to renal dipeptidase (RDPase) (EC 3.4.13.19) was compared with that of imipenem and meropenem by V(max)/K(m) ratios as an index of the enzyme's preference for substrates. Our results showed a decreasing order of imipenem (6.24), meropenem (2.41), and DA-1131 (1.39). The biochemical evaluation of DA-1131 as the least preferred substrate of RDPase suggests its potential use as a novel beta-lactam antibiotic which may be usable without coadministration of RDPase inhibitors once its clinical suitability is proven. PMID:11796382

  4. Arbitrary Amplitude DIA and DA Solitary Waves in Adiabatic Dusty Plasmas

    SciTech Connect

    Mamun, A. A.; Jahan, N.; Shukla, P. K.

    2008-10-15

    The dust-ion-acoustic (DIA) as well as the dust-acoustic (DA) solitary waves (SWs) in an adiabatic dusty plasma are investigated by the pseudo-potential approach which is valid for arbitrary amplitude SWs. The role of the adiabaticity of electrons and ions in modifying the basic features (polarity, speed, amplitude and width) of arbitrary amplitude DIA and DA SWs are explicitly examined. It is found that the effects of the adiabaticity of electrons and ions significantly modify the basic features (polarity, speed, amplitude and width) of the DIA and DA SWs. The implications of our results in space and laboratory dusty plasmas are briefly discussed.

  5. Representando o Irrepresentável: Encenações de Tortura no Teatro Brasileiro da Ditadura Militar

    E-print Network

    Albuquerque, Severino Joã o

    1987-10-01

    -se os gritos de Glauco provocados pelos ataques do "Homem de Botas" (81-83). Como a vítima FALL 1987 9 nada diz, suas reações nos são veiculadas indiretamente, através da única fala do "Homem de Botas" em toda a peça: (A mão direita sobre uma chave..., desta vez a mudança de volta para o presente não se efetua através da iluminação e consequente desaparecimento dos torturadores, mas sim pela entrada da empregada de Papa, Grissa, que "traz dois ou três uniformes, chapéus de chofer, botas" (23) para...

  6. O Prazer da Influência: John Gay, Bertolt Brecht e Chico Buarque de Hollanda

    E-print Network

    Bernucci, Leopoldo M.

    1994-04-01

    desaparecimento {o malandro já era . ..); e outra que se aproximasse da esfera discursiva, literária e canónica que o acolhe, ou seja, do universo das narrativas de um género no qual um indivíduo espertalhão desempenha um papel principal. A história das três... coloca as duas rivais em pé de igualdade e em ato de contrição. Não se defende a honra aqui porque ela obviamente não existe e no pior dos casos a sua presença nos faria recordar que estamos no mundo da ópera-bufa, mantendo-nos no doce sonho da ficção...

  7. Near-UV absorption in very cool DA white dwarfs

    SciTech Connect

    Saumon, D.; Holberg, J. B.; Kowalski, P. M. E-mail: holberg@argus.lpl.arizona.edu

    2014-07-20

    The atmospheres of very cool, hydrogen-rich white dwarfs (WDs) (T{sub eff} < 6000 K) are challenging to model because of the increased complexity of the equation of state, chemical equilibrium, and opacity sources in a low-temperature, weakly ionized dense gas. In particular, many models that assume relatively simple models for the broadening of atomic levels and mostly ideal gas physics overestimate the flux in the blue part of their spectra. A solution to this problem that has met with some success is that additional opacity at short wavelengths comes for the extreme broadening of the Lyman ? line of atomic H by collisions primarily with H{sub 2}. For the purpose of validating this model more rigorously, we acquired Hubble Space Telescope STIS spectra of eight very cool WDs (five DA and three DC stars). Combined with their known parallaxes, BVRIJHK, and Spitzer IRAC photometry, we analyze their entire spectral energy distribution (from 0.24 to 9.3 ?m) with a large grid of model atmospheres and synthetic spectra. We find that the red wing of the Lyman ? line reproduces the rapidly decreasing near-UV flux of these very cool stars very well. We determine better constrained values of T{sub eff} and gravity as well as upper limits to the helium abundance in their atmospheres.

  8. Granite geomorphology and its geological controls, Serra da Estrela, Portugal

    NASA Astrophysics Data System (ADS)

    Migo?, Piotr; Vieira, Gonçalo

    2014-12-01

    Serra da Estrela is an elevated granite massif in central Portugal, characterized by extensive plateau surfaces incised by deep valleys affected by Quaternary glaciation, bounded by steep fault-generated escarpments. The presence of seven major textural variants of granite provides an opportunity to study the relationships between lithology and relief, whereas DEM analysis helped to show the relationships between lithology and topography objectively. The higher ground is associated with fine- to medium-grained granites and is typified by planar surfaces of low gradient, with occasional angular tors and rock pedestals. Block fields built by angular material are common in the parts that were not previously glaciated. Less elevated parts of the plateau are supported by medium- to coarse-grained granites and show more varied topography, with an abundance of tors, boulder piles, and depressions. Lithological boundaries locally coincide with slope breaks but this is not the rule. In the northern part of the massif a deep topographic basin has evolved in biotite granite, whereas deeply incised valleys follow major fault lines. Geological controls show a hierarchy, in that gross relief reflects the pattern of tectonic uplift and subsidence, whereas lithology and then fracture patterns become more and more important if one focuses on smaller and smaller landforms.

  9. DA?NE operation with electron-cloud-clearing electrodes.

    PubMed

    Alesini, D; Drago, A; Gallo, A; Guiducci, S; Milardi, C; Stella, A; Zobov, M; De Santis, S; Demma, T; Raimondi, P

    2013-03-22

    The effects of an electron cloud (e-cloud) on beam dynamics are one of the major factors limiting performances of high intensity positron, proton, and ion storage rings. In the electron-positron collider DA?NE, namely, a horizontal beam instability due to the electron-cloud effect has been identified as one of the main limitations on the maximum stored positron beam current and as a source of beam quality deterioration. During the last machine shutdown in order to mitigate such instability, special electrodes have been inserted in all dipole and wiggler magnets of the positron ring. It has been the first installation all over the world of this type since long metallic electrodes have been installed in all arcs of the collider positron ring and are currently used during the machine operation in collision. This has allowed a number of unprecedented measurements (e-cloud instabilities growth rate, transverse beam size variation, tune shifts along the bunch train) where the e-cloud contribution is clearly evidenced by turning the electrodes on and off. In this Letter we briefly describe a novel design of the electrodes, while the main focus is on experimental measurements. Here we report all results that clearly indicate the effectiveness of the electrodes for e-cloud suppression. PMID:25166811

  10. Evolving understanding of translocator protein 18 kDa (TSPO).

    PubMed

    Li, Fei; Liu, Jian; Garavito, R Michael; Ferguson-Miller, Shelagh

    2015-09-01

    The translocator protein 18 kDa (TSPO) has been the focus of intense research by the biomedical community and the pharmaceutical industry because of its apparent involvement in many disease-related processes. These include steroidogenesis, apoptosis, inflammation, neurological disease and cancer, resulting in the use of TSPO as a biomarker and its potential as a drug target. Despite more than 30 years of study, the precise function of TSPO remains elusive. A recent breakthrough in determining the high-resolution crystal structures of bacterial homologs of mitochondrial TSPO provides new insight into the structural and functional properties at a molecular level and new opportunities for investigating the significance of this ancient and highly conserved protein family. The availability of atomic level structural information from different species also provides a platform for structure-based drug development. Here we briefly review current knowledge regarding TSPO and the implications of the new structures with respect to hypotheses and controversies in the field. PMID:25882248

  11. Voltammetric classification of ciders with PLS-DA.

    PubMed

    Górski, ?ukasz; Sordo?, Wanda; Ciepiela, Filip; Kubiak, W?adys?aw W; Jakubowska, Ma?gorzata

    2016-01-01

    Voltammograms recorded on the glassy carbon electrode (GCE) may be a chemical fingerprints of food samples, enabled distinguishing the origin of the considered products. In this work the objects of the study was 5 Polish ciders of various brands. For each sample 10 scans were recorded by DPV in the potential range between -0.2 and 1.0V in Britton-Robinson buffer at pH 2.0. The signals preprocessing realized by baseline correction with 4-th degree polynomial and normalization (in 0 to 1 interval), performed to reduce problems with insufficient signal's repeatability associated with mechanical renovation of the electrode surface before each measurement. The PLS-DA classification models were built using the training set and then validated using the samples absent in the learning process. The final multi-class model with optimized complexity enables classification of the ciders with 100% sensitivity and specificity, with the exception of one cider, where specificity was 95% (for validation set). PMID:26695257

  12. DA WHITE DWARFS OBSERVED IN THE LAMOST PILOT SURVEY

    SciTech Connect

    Zhang Yueyang; Deng Licai; Liu Chao; Carrell, Kenneth; Yang Fan; Gao Shuang; Xu Yan; Li Jing; Zhang Haotong; Zhao Yongheng; Luo Ali; Bai Zhongrui; Yuan Hailong; Lepine, Sebastien; Newberg, Heidi Jo; Carlin, Jeffrey L.; Jin Ge

    2013-08-01

    A total of {approx}640, 000 objects from the LAMOST pilot survey have been publicly released. In this work, we present a catalog of DA white dwarfs (DAWDs) from the entire pilot survey. We outline a new algorithm for the selection of white dwarfs (WDs) by fitting Sersic profiles to the Balmer H{beta}, H{gamma}, and H{delta} lines of the spectra, and calculating the equivalent width of the Ca II K line. Two thousand nine hundred sixty-four candidates are selected by constraining the fitting parameters and the equivalent width of the Ca II K line. All the spectra of candidates are visually inspected. We identify 230 DAWDs (59 of which are already included in the Villanova and SDSS WD catalogs), 20 of which are DAWDs with non-degenerate companions. In addition, 128 candidates are classified as DAWDs/subdwarfs, which means the classifications are ambiguous. The result is consistent with the expected DAWD number estimated based on the LEGUE target selection algorithm.

  13. Da\\phi ne gamma-rays factory

    E-print Network

    Alesini, D; Variola, A; Guiducci, S; Zomer, F; Milardi, C; Zobov, M

    2014-01-01

    Gamma sources with high flux and spectral densities are the main requirements for new nuclear physics experiments to be performed in several worldwide laboratories and envisaged in the ELI-NP (Extreme Light Infrastructure-Nuclear Physics) project or in the IRIDE (Interdisciplinary Research Infrastructure with Dual Electron Linacs) proposals. The paper is focalized on an experiment of gamma photons production using Compton collisions between the DA\\Phi NE electron beam and a high average power laser pulse, amplified in a Fabry-P\\'erot optical resonator. The calculations show that the resulting gamma beam source has extremely interesting properties in terms of spectral density, energy spread and gamma flux comparable (and even better) with the last generation gamma sources. The energy of the gamma beam depends on the adopted laser wavelength and can be tuned changing the energy of the electron ring. In particular we have analyzed the case of a gamma factory tunable in the 2-9 MeV range. The main parameters of t...

  14. Identifying nude pictures D.A. Forsyth M.M. Fleck

    E-print Network

    Fleck, Margaret M.

    Identifying nude pictures D.A. Forsyth M.M. Fleck Computer Science Division Department of Computer background (e.g. [?]); there is little work on segmentation. None of these systems is suitable for analyzing

  15. Thinking like Leonardo da Vinci and its implications for the modern doctor.

    PubMed

    Baum, Neil

    2013-01-01

    Most people when asked to name the most creative, innovative, and multidimensional people in history would agree that Leonardo da Vinci is either at the top or very close to the number one position on that list. Wouldn't it be nice to think like da Vinci? This article shares the seven unique principles of thinking that da Vinci used that enabled him to be the greatest painter, sculptor, architect, musician, mathematician, engineer, inventor, anatomist, geologist, cartographer, botanist, and writer of his (if not of all) time. This article will take you deep into the notebooks and codices of da Vinci, and suggest ways his ideas can be used by anyone in the healthcare profession to make them a better healthcare provider. PMID:24228380

  16. Cortes adicionais no ensino superior vista oramento Para alm da re-

    E-print Network

    Instituto de Sistemas e Robotica

    Ensino Superior, José Ferreira Gomes, ad- mitiu ontem, à agência Lusa, que as transferências de dinheiro dinheiro para ter uma universidade em cada cidade". A Reorganização da Rede de En- sino Superior também foi

  17. Area Efficient D/A Converters For Accurate DC Operation Brandon Royce Greenley

    E-print Network

    Moon, Un-Ku

    . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 6.2 Mismatch Modeling For Area Optimization . . . . . . . . . . . . . . . . . . . . . . . 51 6Area Efficient D/A Converters For Accurate DC Operation by Brandon Royce Greenley A THESIS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 5.1 Measurement Setup

  18. 32 CFR 516.14 - Service of process on DA or Secretary of Army.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Service of Process § 516.14 Service of process on DA or Secretary of Army. The Chief,...

  19. PARECER HOMOLOGADO(*) (*) Despacho do Ministro, publicado no Dirio Oficial da Unio de 09/07/2007

    E-print Network

    Floeter, Sergio Ricardo

    dos princípios, fins e objetivos do Tratado de Assunção, assinado em março de 1991, CONSIDERANDO: Que Reunião de Ministros da Educação dos Países Signatários do Tratado do Mercado Comum do Sul, realizada em

  20. DaG 1066: A Newfound Anomalous Ureilite with Chondritic Inclusions

    NASA Astrophysics Data System (ADS)

    Moggi Cecchi, V.; Caporali, S.; Pratesi, G.

    2015-07-01

    General description, textural, and compositional features of the polymict ureilite DaG 1066, recovered in 1999 in Libya, are provided. The meteorite contains various inclusions, among which almost pure forsterite and enstatite-bearing chondrules.

  1. The China-in-Global Energy Model Tianyu Qi, Niven Winchester, Da Zhang,

    E-print Network

    The China-in-Global Energy Model Tianyu Qi, Niven Winchester, Da Zhang, Xiliang Zhang and Valerie J: globalchange@mit.edu Website: http://globalchange.mit.edu/ #12;1 The China-in-Global Energy Model Tianyu Qi

  2. 32 CFR 635.23 - DA Form 4833 (Commander's Report of Disciplinary or Administrative Action).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Director of Emergency Services initiates this critical document and is responsible for its distribution...signature block of DA Form 4833 that contains the word “Commanding” will be deleted and the word “Reporting” substituted. The Provost...

  3. AVALIAÇÃO DA PRESENÇA DE ENDOSSIMBIONTES Cardinium em DIFERENTES ESPÉCIES DE ARTRÓPODES.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A presença de endossimbiontes do gênero Cardinium em alguns grupos de artrópodes foi recentemente relatada e relacionada com diversas alterações reprodutivas em seus hospedeiros, tais como feminilização de ácaros, partenogênese em parasitóides, incompatibilidade citoplasmática e aumento da fecundida...

  4. Analise Matematica III A Ficha 1 Derivac~ao em Rn, Teoremas da Func~ao Inversa e da Func~ao Implicita

    E-print Network

    Ventura, Joana

    An´alise Matem´atica III A ­ Ficha 1 Deriva¸c~ao em Rn, Teoremas da Fun¸c~ao Inversa e da Fun¸c~ao Impl´icita 1. Seja f : R2 R uma fun¸c~ao de classe C2. Seja F(x, y) = f(x3 - y, x2y). Sabendo que f(2, -1) = (1, 4), calcule F(1, -1). 2. Sejam f, g : R R duas fun¸c~oes de classe C2. Seja F(x, y) = f

  5. Temperature and Gravity Dependence of Trace Element Abundances in Hot DA White Dwarfs (94-EUVE-094)

    NASA Technical Reports Server (NTRS)

    Finley, David S.

    1998-01-01

    EUV spectroscopy has shown that DA white dwarfs hotter than about 45,000 K may contain trace heavy elements, while those hotter than about 50,000 K almost always have significant abundances of trace heavy elements. One of our continuing challenges is to identify and determine the abundances of these trace constituents, and then to relate the observed abundance patterns to the present conditions and previous evolutionary histories of the hot DA white dwarfs.

  6. Load evaluation of the da Vinci surgical system for transoral robotic surgery.

    PubMed

    Fujiwara, Kazunori; Fukuhara, Takahiro; Niimi, Koji; Sato, Takahiro; Kitano, Hiroya

    2015-12-01

    Transoral robotic surgery, performed with the da Vinci surgical system (da Vinci), is a surgical approach for benign and malignant lesions of the oral cavity and laryngopharynx. It provides several unique advantages, which include a 3-dimensional magnified view and ability to see and work around curves or angles. However, the current da Vinci surgical system does not provide haptic feedback. This is problematic because the potential risks specific to the transoral use of the da Vinci include tooth injury, mucosal laceration, ocular injury and mandibular fracture. To assess the potential for intraoperative injuries, we measured the load of the endoscope and the instrument of the da Vinci Si surgical system. We pressed the endoscope and instrument of the da Vinci Si against Load cell six times each and measured the dynamic load and the time-to-maximum load. We also struck the da Vinci Si endoscope and instrument against the Load cell six times each and measured the impact load. The maximum dynamic load was 7.27 ± 1.31 kg for the endoscope and 1.90 ± 0.72 for the instrument. The corresponding time-to-maximum loads were 1.72 ± 0.22 and 1.29 ± 0.34 s, but the impact loads were significantly lower than the dynamic load. It remains possible that a major load is exerted on adjacent structures by continuous contact with the endoscope and instrument of da Vinci Si. However, there is a minor delay in reaching the maximum load. Careful monitoring by an on-site assistant may, therefore, help prevent contiguous injury. PMID:26530845

  7. PAN-DA and beyond: Data acquisition for the next generation experiments

    SciTech Connect

    Pordes, R.; Anderson, J.; Berg, D.; Berman, E.; Brown, D.; Dorries, T.; Mackinnon, B.; Meadows, J.; Moore, C.; Nicinski, T.; Oleynik, G.; Petravick, D.; Rechenmacher, R.; Sergey, G.; Slimmer, D.; Streets, J.; Vittone, M.; Votava, M.; Wilcer, N.; White, V.

    1991-06-01

    We report on the status of the PAN-DA data acquisition system presented at the last Real Time Conference. Since that time, PAN-DA has been successfully used in the fixed target program at Fermilab. We also report on the plans and strategies for development of a new data acquisition system for the next generation of fixed target experiments at Fermilab. 10 refs., 3 figs.

  8. An antibody against 100- to 116-kDa polypeptides in coated vesicles inhibits triskelion binding

    SciTech Connect

    Mosley, S.T.; Branton, D. )

    1988-02-01

    There is considerable evidence that the 100- to 116-kDa polypeptides in calf brain coated vesicles are involved in the assembly of clathrin triskelions to form coated vesicles. The authors have raised polyclonal antibodies against these polypeptides. By Western blot analysis, these antibodies bind to a distinct subset of the six polypeptides in the region 100-116 kDa. Whole cell homogenates from calf brain, calf liver, and rat liver also show immunoreactivity in the 100-kDa region with no other cross reactivity. Isolated coated vesicles from calf liver, rat brain, and soybean roots also cross-react. Stripped coated vesicles, which are depleted of clathrin but which retain the 100- to 116-kDa polypeptides, quantitatively rebind {sup 125}I-triskelions. These studies indicate that (1) specific sites on the 100- to 116-kDa polypeptides are required for assembly of coated vesicles, and (2) this antibody will be useful in clarifying more precisely the role of the 100- to 116-kDa polypeptides in coated vesicle recycling.

  9. The sandfly fauna (Diptera: Psychodidae: Phlebotominae) of the Parque Estadual da Serra da Tiririca, Rio de Janeiro, Brazil

    PubMed Central

    Rodrigues, Andressa Alencastre Fuzari; Barbosa, Vanessa de Araújo; Andrade, José Dilermando; Brazil, Reginaldo Peçanha

    2013-01-01

    Cutaneous leishmaniasis (CL) in the state of Rio de Janeiro is sporadic and can be characterised as a peridomestic transmission that occurs in modified natural environments. The aim of this work was to study the fauna and ecological characteristics of sandflies in an environmentally protected area (the State Park of Serra da Tiririca) within the remnants of the Atlantic Forest in the municipalities of Niterói and Maricá and their possible relationship with leishmaniasis. Captures were performed using light traps during the night once a month for one year in both sylvatic environments and areas surrounding homes near the park. A total of 1,037 sandflies were captured, belonging to nine genera and 12 species: Evandromyia tupynambai (34.1%), Migonemyia migonei (20.6%), Brumptomyia cunhai (13.8%), Micropygomyia schreiberi (9.7%), Psathyromyia lanei (6.5%), Brumptomyia nitzulescui (5.7%), Evandromyia edwardsi (5.4%), Nyssomyia intermedia (2.8%), Evandromyia cortelezzii (0.6%), Pintomyia bianchigalatiae (0.5%), Lutzomyia longipalpis (0.2%) and Sciopemyia microps (0.1%). Both Mg. migonei and Ny. intermedia may be acting as vectors of CL in this area. PMID:24141956

  10. D-amphetamine (A)-induced dopamine (DA) release is not strictly dependent on newly-synthesized transmitter

    SciTech Connect

    Parker, E.; Cubeddu, L.

    1986-03-05

    A is thought to exert its stimulant effects by releasing DA from a newly synthesized transmitter pool. This hypothesis was evaluated directly by measuring the basal efflux and electrically-evoked release of endogenous DA and dihydroxyphenylacetic acid (DOPAC). In striatal slices from reserpine-treated rabbits A increased DA efflux, reduced DOPAC efflux, and inhibited electrically-evoked /sup 3/H-ACh release in a concentration-dependent manner. These effects could not be mimicked by inhibition of neuronal uptake or MAO, but were blocked by inhibition of DA synthesis or neuronal uptake, and were potentiated by inhibition of MAO. In slices with intact vesicular transmitter stores A induced DA efflux was 2-fold greater than that seen in slices having no vesicular stores. Inhibition of DA synthesis reduced A-induced DA efflux by 60%, but had little effect on the ability of A to inhibit /sup 3/H-ACh release. A also increased the electrical stimulation-evoked overflow of DA (an effect which was attenuated slightly by synthesis inhibition), and potently inhibited DOPAC overflow. These results suggest that: 1) A facilitates efflux of axoplasmic DA by an accelerated exchange diffusion mechanism. The releasable axoplasmic pool is derived from newly synthesized and vesicular transmitter pools; 2) postsynaptic indices of transmitter release may be misleading; and 3) A increases electrically-evoked DA release possibly by inhibiting neuronal uptake.

  11. Antiapoptotic activity of 30 kDa lipoproteins family from fat body tissue of silkworm, Bombyx mori.

    PubMed

    Pakkianathan, Britto Cathrin; Singh, Nitin Kumar; König, Simone; Krishnan, Muthukalingan

    2015-10-01

    The family of 30?kDa lipoproteins (LP1-5) is abundant in silkworm pupa fat body (FB) and hemolymph. One of its members, the 29?kDa protein decreased in concentration from peripheral (PP) FB tissue but was sustained in perivisceral (PV) FB tissue at the time of apoptosis. This study investigated the correlation of the 30?kDa proteins with FB apoptosis. Two protein fractions were purified, a 29 and a 30/31?kDa protein fraction, and they were used to test for activity against actinomycin D-induced apoptosis in the FB tissues. Concentrations as little as 50??g/mL of the 29?kDa protein fraction efficiently inhibited apoptosis. Less antiapoptotic activity was detected for the higher MW fraction; DNA fragmentation was observed in FB tissue treated with 50??g/mL of the 30/31?kDa fraction. The viability of the cells in the 29?kDa protein-supplemented culture was 40% higher than in the 31?kDa protein-supplemented culture. However, the 30?kDa lipoproteins were not able to prevent scheduled FB degeneration during silkworm metamorphosis. Thus, it is hypothesized that the antiapoptotic 29?kDa protein needs to be proteolytically degraded by a regulatory mechanism to allow programmed cell death of FB tissue. PMID:24591444

  12. Lista de Presena da 225 Reunio da Cmara de Carreira Docente, realizada em 1/12/2014 N NOME CARGO/FUNO ASSINATURA

    E-print Network

    Maier, Rudolf Richard

    CARGO/FUNÇÃO ASSINATURA 01 Sônia Nair Báo Vice-Reitor 02 Jaime Martins Santana Decano/DPP 03 Mauro Luiz Toledo 12 Brasilmar Ferreira Nunes Rep. da ICS/SOL 13 Davi Monteiro Diniz Carlos Tadeu de Carvalho Rep Castioni ADUnB Carlos Eduardo Vidigal ADUnB #12;#12;

  13. Purification and characterization of 33.5 kDa vesicular protein in human bile

    PubMed Central

    Xiang, Jian-Bin; Cai, Duan; Ma, Bao-Jin; Cha, Xi-Liang; Wang, Li-Ying; Mo, Han-Qing; Zhang, Yan-Ling

    2003-01-01

    AIM: The present study was undertaken to purify and partially characterize the 33.5-kilodalton (33.5 kDa) vesicular protein in human bile and to explore the possible molecular mechanisms of the initial crystal nucleation process. METHODS: The 33.5 kDa vesicular protein was isolated by ultracentrifugation and further purified by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) under nonreducing conditions. The purified 33.5 kDa vesicular protein was subjected to N-terminal amino acid sequencing and amino acid analysis. Cholesterol crystallization activity was detected by cholesterol crystal growth assay. The sugar chain of the 33.5 kDa vesicular protein was analyzed by dot-immunobinding assay of lectin coupled to a peroxidase (HRP-DSA, HRP-ConA, HRP-WGA) and was deglycosylated using two different enzymatic approaches (N-deglycosylation and O-deglycosylation) to determine the molecular weight of the protein component, the type of linkage between polypeptide and carbohydrate components. RESULTS: The 33.5 kDa vesicular protein with complicated glycan was an extensively glycosylated (37.3%) monomer and these sugar chains strongly bound to DSA, but did not bind to ConA. Amino acid sequencing indicated that the protein was unique. The 33.5 kDa vesicular protein exhibited potent cholesterol crystallization promoting activity in vitro with derived crystal growth curve indices It, Ig, Ic presented as 0.57, 1.52, and 1.63 respectively. Both enzymatic proteolysis and N-deglycosylation of the protein removed all activity. CONCLUSION: These data suggest the 33.5 kDa vesicular protein may be responsible for the pathogenesis of cholesterol gallstone disease, and the sugar chains play an important role in pro-nucleating process. PMID:14606092

  14. Católicos, fidelidade conjugal e AIDS: entre a cruz da doutrina moral e as espadas do cotidiano sexual dos adeptos1

    PubMed Central

    Rios, Luis Felipe; de Aquino, Francisca Luciana; Muñoz-Laboy, Miguel; Oliveira, Cinthia; Parker, Richard

    2009-01-01

    Neste artigo discutimos a visão da Igreja Católica sobre sexualidade na interface com a epidemia do HIV/AIDS. Nossa reflexão está embasada em pesquisa etnográfica que envolveu dois meses de observação participante do cotidiano de católicos de um bairro popular da Região Metropolitana do Recife, além de contar com entrevistas a onze dos leigos engajados nos serviços religiosos da igreja do bairro e a oito sacerdotes que realizam seus trabalhos religiosos em outras localidades. Nelas abordamos diferentes temáticas relacionadas ao enfrentamento da epidemia da AIDS. Nesse contexto, conjugalidade e fidelidade se afiguram como importantes analisadores de como aqueles lidam com a epidemia, em uma variedade de re-descrições práticas e de re-interpretações conceptuais das assertivas do discurso moral religioso – ainda que, muitos impasses permaneçam em aberto em termos das prerrogativas da Igreja e seus possíveis rebatimentos na saúde sexual dos adeptos. PMID:21765650

  15. Percepção Astronômica de Alunos do Ensino Médio da Rede Estadual de São Paulo

    NASA Astrophysics Data System (ADS)

    de Oliveira, E. F.; Voelzke, M. R.; Amaral, L. H.

    2005-08-01

    Embora a astronomia seja uma das ciências mais antigas da humanidade e muitos dos conceitos astronômicos serem populares, principalmente nesta época de alta globalização do conhecimento por intermédio de eficientes meios de comunicação e de obtenção da informação, notadamente através da internet, observa-se que uma parcela significativa dos estudantes encontra-se à margem dessas informações. O presente trabalho visa analisar o nível de conhecimento básico dos alunos de Ensino Médio da rede estadual da cidade de Suzano quanto aos fenômenos astronômicos que os rodeiam, tais como a sucessão dos dias e das estações do ano, além de questioná-los sobre fatos genéricos tais como: quais são os astros que se encontram mais próximos do planeta Terra, o que vem a ser o Sol, o Big Bang, um ano-luz, uma estrela cadente, a estrela de Bélem e o que ocasionou a extinção dos dinossauros. Para tanto foi elaborado um formulário constando de questões de múltipla escolha, o qual foi aplicado no primeiro colegial noturno da Escola Estadual Batista Renzi. Num espaço amostral de 34 alunos constatou-se que apenas 29,4% compreendiam a sucessão dos dias da semana, que apenas 20,6% explicaram corretamente as estações do ano, que apenas 20,6% tinham idéia de quais são os objetos celestes mais próximos da Terra, em contraposição 67,6% sabiam classificar corretamente o Sol como estrela, 55,9% relacionavam o Big Bang à origem do universo, apenas 20,6% identificavam um ano-luz como unidade de distância, 32,4% reconheciam uma estrela cadente como meteoro, 41,2% consideravam a estrela de Belém como um cometa e 50,0% explicaram corretamente a extinção dos dinossauros. A presente análise será expandida para as demais classes de primeiro colegial, não somente do período noturno, mas também do diurno da Escola Estadual Batista Renzi, bem como o formulário será devidamente ampliado. Já nesta primeira fase nota-se claramente o pequeno discernimento de eventos astronômicos dos alunos e principalmente a grande confusão sobre o significado correto de termos astronômicos populares.

  16. Extending the ATLAS PanDA Workload Management System for New Big Data Applications

    E-print Network

    De, K; The ATLAS collaboration; Maeno, T; Nilsson, P; Panitkin, S; Vaniachine, A; Wenaus, T; Yu, D

    2013-01-01

    The LHC experiments are today at the leading edge of large scale distributed data-intensive computational science. The LHC's ATLAS experiment processes data volumes which are particularly extreme, over 130 PB to date, distributed worldwide at over of 120 sites. An important element in the success of the exciting physics results from ATLAS is the highly scalable integrated workflow and dataflow management afforded by the PanDA workload management system, used for all the distributed computing needs of the experiment. The PanDA design is not experiment specific and PanDA is now being extended to support other data intensive scientific applications. Alpha-Magnetic Spectrometer, an astro-particle experiment on the International Space Station, and the Compact Muon Solenoid, an LHC experiment, have successfully evaluated PanDA and are pursuing its adoption. PanDA was cited as an example of "a high performance, fault tolerant software for fast, scalable access to data repositories of many kinds" during the "Big Data...

  17. Integration of PanDA workload management system with Titan supercomputer at OLCF

    E-print Network

    De, Kaushik; The ATLAS collaboration; Oleynik, Danila; Panitkin, Sergey; Petrosyan, Artem; Vaniachine, Alexandre; Wenaus, Torre; Schovancova, Jaroslava

    2015-01-01

    The PanDA (Production and Distributed Analysis) workload management system (WMS) was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. While PanDA currently distributes jobs to more than 100,000 cores at well over 100 Grid sites, next LHC data taking run will require more resources than Grid computing can possibly provide. To alleviate these challenges, ATLAS is engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF). Current approach utilizes modi ed PanDA pilot framework for job submission to Titan's batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on Titan's multi-core worker nodes. It also gives PanDA new capability to collect, in real time, information about unused...

  18. Integration of PanDA workload management system with Titan supercomputer at OLCF

    E-print Network

    Panitkin, Sergey; The ATLAS collaboration; Klimentov, Alexei; Oleynik, Danila; Petrosyan, Artem; Schovancova, Jaroslava; Vaniachine, Alexandre; Wenaus, Torre

    2015-01-01

    The PanDA (Production and Distributed Analysis) workload management system (WMS) was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. While PanDA currently uses more than 100,000 cores at well over 100 Grid sites with a peak performance of 0.3 petaFLOPS, next LHC data taking run will require more resources than Grid computing can possibly provide. To alleviate these challenges, ATLAS is engaged in an ambitious program to expand the current computing model to include additional resources such as the opportunistic use of supercomputers. We will describe a project aimed at integration of PanDA WMS with Titan supercomputer at Oak Ridge Leadership Computing Facility (OLCF). Current approach utilizes modified PanDA pilot framework for job submission to Titan's batch queues and local data management, with light-weight MPI wrappers to run single threaded workloads in parallel on Titan's multi-core worker nodes. It also gives PanDA new capability to collect, in real tim...

  19. Low strain, long life creep fatigue of AF2-1DA and INCO 718

    NASA Technical Reports Server (NTRS)

    Thakker, A. B.; Cowles, B. A.

    1983-01-01

    Two aircraft turbine disk alloys, GATORIZED AF2-DA and INCO 718 were evaluated for their low strain long life creep-fatigue behavior. Static (tensile and creep rupture) and cyclic properties of both alloys were characterized. The cntrolled strain LCF tests were conducted at 760 C (1400 F) and 649 C (1200 F) for AF2-1DA and INCO 718, respectively. Hold times were varied for tensile, compressive and tensile/compressive strain dwell (relaxation) tests. Stress (creep) hold behavior of AF2-1DA was also evaluated. Generally, INCO 718 exhibited more pronounced reduction in cyclic life due to hold than AF2-1DA. The percent reduction in life for both alloys for strain dwell tests was greater at low strain ranges (longer life regime). Changing hold time from 0 to 0.5, 2.0 and 15.0 min. resulted in corresponding reductions in life. The continuous cycle and cyclic/dwell initiation failure mechanism was predominantly transgranular for AF2-1DA and intergranular for INCO 718.

  20. Fluorescence spectroscopy coupled with PARAFAC and PLS DA for characterization and classification of honey.

    PubMed

    Lenhardt, Lea; Bro, Rasmus; Zekovi?, Ivana; Drami?anin, Tatjana; Drami?anin, Miroslav D

    2015-05-15

    Fluorescence spectroscopy coupled with parallel factor analysis (PARAFAC) and Partial least squares Discriminant Analysis (PLS DA) were used for characterization and classification of honey. Excitation emission spectra were obtained for 95 honey samples of different botanical origin (acacia, sunflower, linden, meadow, and fake honey) by recording emission from 270 to 640 nm with excitation in the range of 240-500 nm. The number of fluorophores present in honey, excitation and emission spectra of each fluorophore, and their relative concentration are determined using a six-component PARAFAC model. Emissions from phenolic compounds and Maillard reaction products exhibited the largest difference among classes of honey of different botanical origin. The PLS DA classification model, constructed from PARAFAC model scores, detected fake honey samples with 100% sensitivity and specificity. Honey samples were also classified using PLS DA with errors of 0.5% for linden, 10% for acacia, and about 20% for both sunflower and meadow mix. PMID:25577082

  1. Trypanosoma cruzi uses a 45-kDa mucin for adhesion to mammalian cells.

    PubMed

    Turner, Corey W; Lima, Maria F; Villalta, Fernando

    2002-01-11

    A set of monoclonal antibodies that recognizes a Trypanosoma cruzi 45-kDa protein was produced and used to characterize this molecule and study its role in trypanosome adhesion to heart myoblasts. We found that the 45-kDa protein is a surface mucin, is expressed only in invasive trypomastigotes, but not in noninvasive epimastigotes or amastigotes, and is released by the trypanosome in culture medium. One of the monoclonal antibodies (Mab B5) from this set inhibits the attachment of trypomastigotes to heart myoblasts preventing trypanosome entry, whereas the others (Mabs B4 and F1) do not. This inhibition was seen with the B5 hybridoma culture supernatant, with the purified Mab B5 IgG or with Mab B5 Fab fragments. These novel findings identify the 45-kDa mucin as a new T. cruzi ligand that is used by invasive forms of this organism to adhere to heart myoblasts. PMID:11779128

  2. Detection of trace helium in G104 - 27, a 26,000 K DA white dwarf

    NASA Technical Reports Server (NTRS)

    Holberg, J. B.; Kidder, K. M.; Wesemael, F.

    1990-01-01

    The detection of the He I 4471 A feature in the moderately hot DA white dwarf G104 - 27 places this star within the rather sparse class of DAB white dwarfs. It does not appear possible, on the basis of the present data, to distinguish between a stratified and a homogeneously mixed atmosphere. While a stratified structure would be natural for a DA white dwarf, G104 - 27 resides near the red edge of the DB gap, in a region where DA stars could transform into DB stars through convective mixing in the underlying He envelope and thereby destroy envelope stratification. Both atmospheres are consistent with the existing soft X-ray flux limit for this star.

  3. The Da Vinci European BioBank: A Metabolomics-Driven Infrastructure

    PubMed Central

    Carotenuto, Dario; Luchinat, Claudio; Marcon, Giordana; Rosato, Antonio; Turano, Paola

    2015-01-01

    We present here the organization of the recently-constituted da Vinci European BioBank (daVEB, https://www.davincieuropeanbiobank.org/it). The biobank was created as an infrastructure to support the activities of the Fiorgen Foundation (http://www.fiorgen.net/), a nonprofit organization that promotes research in the field of pharmacogenomics and personalized medicine. The way operating procedures concerning samples and data have been developed at daVEB largely stems from the strong metabolomics connotation of Fiorgen and from the involvement of the scientific collaborators of the foundation in international/European projects aimed to tackle the standardization of pre-analytical procedures and the promotion of data standards in metabolomics. PMID:25913579

  4. gLExec Integration with the ATLAS PanDA Workload Management System

    E-print Network

    Karavakis, Edward; The ATLAS collaboration; Campana, Simone; De, Kaushik; Di Girolamo, Alessandro; Litmaath, Maarten; Maeno, Tadashi; Medrano Llamas, Ramon; Nilsson, Paul; Wenaus, Torre

    2015-01-01

    ATLAS user jobs are executed on Worker Nodes (WNs) by pilots sent to sites by pilot factories. This paradigm serves to allow a high job reliability and although it has clear advantages, such as making the working environment homogeneous, the approach presents security and traceability challenges. To address these challenges, gLExec can be used to let the payloads for each user be executed under a different UNIX user id that uniquely identifies the ATLAS user. This paper describes the recent improvements and evolution of the security model within the ATLAS PanDA system, including improvements in the PanDA pilot, in the PanDA server and their integration with MyProxy, a credential caching system that entitles a person or a service to act in the name of the issuer of the credential. Finally, it presents results from ATLAS user jobs running with gLExec and describes the deployment campaign within ATLAS.

  5. Performance of a 27 kDa Fasciola hepatica Antigen in the Diagnosis of Human Fascioliasis

    PubMed Central

    Shafiei, Reza; Sarkari, Bahador; Sadjjadi, Seyed Mahmoud

    2015-01-01

    Background: Serological diagnosis, based on antigenic fractions of the parasite can be used for the early diagnosis of human fascioliasis. The current study aimed to evaluate the efficacy of a 27 kDa immunodominant antigen of Fasciola hepatica adult worms, in an indirect enzyme-linked immunosorbent assay (ELISA) system for serological diagnosis of human fascioliasis. Materials and Methods: The immunodiagnosis of human fascioliasis, using a 27 kDa immunodominant antigen, purified from F. hepatica somatic antigens (SAs), was evaluated by Western blotting and ELISA with sera samples of human fascioliasis patients, healthy controls and patients with other parasitic infections. Results: Using western blotting, from 12 sera of fascioliasis patients, 11 sera (91.6%) detected the 27 kDa subunit. None of 30 samples from healthy controls or 32 sera from nonfascioliasis patients reacted with the 27 kDa antigen. Accordingly, sensitivity and specificity of the system was found to be 91.6% and 100%, respectively. The 27 kDa antigen was purified from the SAs and was used in an indirect ELISA system. Of 15 sera of fascioliasis patients, all (100%) were found to be positive by ELISA whereas only 4 cases (6.25%) of nonfascioliasis patients or healthy controls were false-positive by this system. Accordingly, the sensitivity and specificity of the test were 100% and 93.6%, respectively. Conclusion: Findings of this study demonstrated that both Western blotting and the indirect ELISA, based on the 27 kDa subunit of F. hepatica SA, are reliable methods for serodiagnosis of human fascioliasis. PMID:25949054

  6. Evolution of robots throughout history from Hephaestus to Da Vinci Robot.

    PubMed

    Iavazzo, Christos; Gkegke, Xanthi-Ekaterini D; Iavazzo, Paraskevi-Evangelia; Gkegkes, Ioannis D

    2014-01-01

    Da Vinci robot is increasingly used for operations adding the advantages of robots to the favor of medicine. This is a historical article with the aim to present the evolution of robots in the medical area from the time of ancient myths to Renaissance and finally to the current revolutionary applications. We endeavored to collect several elegant narratives on the topic. The use of imagination could help the reader to find similarities. A trip from the Greek myths of Hephaestus through Aristotle and Leonardo Da Vinci to the robots of Karel Capek and Isaac Asimov and finally the invention of the medical robots is presented. PMID:25811686

  7. A Study of the Ultraviolet Absorptions in the Spectra of DA White Dwarfs

    NASA Technical Reports Server (NTRS)

    Wegner, G. A.

    1986-01-01

    Systematic investigations of the ultraviolet spectra of the hydrogen-rich white dwarfs were conducted with the International Ultraviolet Explorer satellite (IUE). This is to follow up on the work reported in Nelan and Wegner (1985) that the strong absorptions found earlier near lambda lambda 1600 and 1400 (cf. Greenstein 1980; Wegner 1982 and 1984, b) in the spectra of the cooler DA are absorptions produced by the H2 and H2(+) quasi-molecules. Observations of new DA white dwarfs obtained with the IUE are summarized.

  8. Spectroscopy of the DA white dwarfs - Automatic atmospheric parameterization and mass distribution

    NASA Technical Reports Server (NTRS)

    Mcmahan, Robert K.

    1989-01-01

    A method for the automatic calculation of the atmospheric parameters (Teff and log g) of hydrogen-rich degenerate stars from low-resolution spectra is described, and then applied to the spectra of 53 DA white dwarfs. A value for the width of the DA mass distribution of sigma M/solar-M not greater than +0.10 is obtained using the proposed approach. The data indicate that the distribution is asymmetrically skewed to low masses; however, there is also evidence of a high-mass non-Gaussian tail.

  9. Aerodynamic design of the Cal Poly Da Vinci Human-Powered Helicopter

    NASA Technical Reports Server (NTRS)

    Larwood, Scott; Saiki, Neal

    1990-01-01

    This paper will discuss the methodology used in designing the rotor and drive propellers for the third generation Cal Poly Da Vinci Human-Powered Helicopter. The rotor was designed using a lifting surface, uniform inflow hover analysis code and the propeller was designed using a minimum induced-loss method. Construction, geometry, and operating considerations are discussed as they impact the designs. Optimization of the design performance is also explained. The propellers were tested in a wind tunnel and results are compared with theoretical data. Successful flight tests of the Da Vinci III are discussed.

  10. Detection and differentiation of 22 kDa and 20 kDa Growth Hormone proteoforms in human plasma by LC-MS/MS.

    PubMed

    Such-Sanmartín, Gerard; Bache, Nicolai; Bosch, Jaume; Gutiérrez-Gallego, Ricardo; Segura, Jordi; Jensen, Ole N

    2015-04-01

    Human growth hormone (GH) is suspected to be widely and illegally used in sport to improve athletes' performance. For the detection of GH abuse, blood samples are screened for abnormal ratios between the 22 and 20 kDa GH proteoforms that demonstrate the administration of the synthetic hormone. Current detection methods are based on classical immunoassays as they provide sufficient sensitivity for the detection of GH proteoforms. These antibody based methods, however, suffer from unclear selectivity and potential cross-reactivity towards similar proteins. For unambiguous GH detection, we report a Mass Spectrometry ImmunoAssay (MSIA) that first enriches GH from plasma with an antibody of relatively low specificity, and subsequently quantifies the 22 and 20 kDa proteoforms by Selected Reaction Monitoring (SRM) LC-MS/MS analysis. This method proved superior to an antibody-free strategy based on GH purification by protein precipitation. Using GH-MSIA we successfully quantified the 22/20 kDa GH ratio in post-exercise capillary plasma extracted from two individuals. This GH-MSIA is applicable to anti-doping and GH-related disease analysis. PMID:25556001

  11. The Drosophila 110-kDa transcription factor TFIID subunit directly interacts with the N-terminal region of the 230-kDa subunit.

    PubMed Central

    Kokubo, T; Gong, D W; Roeder, R G; Horikoshi, M; Nakatani, Y

    1993-01-01

    Transcription initiation factor TFIID is a multimeric protein complex that plays a central role in transcriptional regulation by facilitating promoter responses to various activators. cDNAs encoding the 110-kDa subunit of Drosophila TFIID (p110) were isolated with a degenerate oligodeoxynucleotide probe based on an amino acid sequence of the purified protein. The entire cDNA sequence contains an open reading frame encoding a 921-amino acid polypeptide with a calculated molecular mass of 99,337 Da. The recombinant protein expressed in Sf9 cells via a baculovirus vector interacts directly with the 230-kDa subunit of TFIID (p230). Together with the previous observation that the TATA box-binding subunit of TFIID (TFIID tau or TBP) interacts directly with only p230 among the TFIID subunits, this result suggests that p110 forms a complex with TFIID tau via p230. A binding study using various p230 mutants indicated that both p110 and TFIID tau interact with the N-terminal 352-amino acid portion of p230, suggesting a functional communication between p110 and TFIID tau via p230 interactions. Images Fig. 2 Fig. 3 Fig. 4 Fig. 5 PMID:8327460

  12. Long-term evolution of 1991 DA: A dynamically evolved extinct Halley-type comet

    NASA Technical Reports Server (NTRS)

    Hahn, Gerhard; Bailey, M. E.

    1992-01-01

    The long-term dynamical evolution of 21 variational orbits for the intermediate-period asteroid 1991 DA was followed for up to +/-10(exp 5) years from the present. 1991 DA is close to the 2:7 resonance with Jupiter; it has avoided close encounters, within 1 AU, with this planet for at least the past 30,000 years, even at the node crossing. The future evolution typically shows no close encounters with Jupiter within at least 50,000 years. This corresponds to the mean time between node crossings with either Jupiter or Saturn. Close encounters with Saturn and Jupiter lead to a chaotic evolution for the whole ensemble, while secular perturbations cause large-amplitude swings in eccentricity and inclination (the latter covering the range 15 deg approximately less than i approximately less than 85 deg) which correlate with deep excursions of the perihelion distance to values much less than 1 AU. These variations are similar to those found in P/Machholz and a variety of other high-inclination orbits, e.g., P/Hartley-IRAS. We emphasize the connection between the orbital evolution of 1991 DA and that of Halley-type comets. If 1991 DA was once a comet, it is not surprising that it is now extinct.

  13. Reoxygenation of mouse mammary carcinoma by Fluosol-DA 20% and carbogen

    SciTech Connect

    Lee, I.

    1988-01-01

    The purpose of this study was to investigate the feasibility of using Fluosol-DA 20% in combination with carbogen inhalation to improve the radiotherapy of SCK tumors in A/J mice. The effect of i.v. injected Fluosol-DA and carbogen inhalation on the response of tumors to single and fractionated irradiation, and that on the changes in hypoxic cell fraction in the tumors were studied. The radiation-induced tumor growth delay and cure was enhanced by a D.M.F. of 2.10 and 1.86, respectively. The treatment slightly increased radiation-induced skin damage by a factor of 1.17 resulting in a therapeutic gain of 1.79 for growth delay and 1.59 for curability. Tumor growth delay by fractionated irradiation was enhanced by Fluosol-DA and carbogen treatment with a D.M.F. of 1.63. The hypoxic cell fraction, as measured with an in vivo-in vitro cloning method, was 39% in control tumors, and it decreased to only 5% in the tumors of animals treated with Fluosol-DA plus carbogen breathing.

  14. Two rubber balloons: Phase diagram of air transfer Yan Levin* and Fernando L. da Silveira

    E-print Network

    Levin, Yan

    Two rubber balloons: Phase diagram of air transfer Yan Levin* and Fernando L. da Silveira Instituto, RS, Brazil (Received 1 December 2003; published 26 May 2004) Two identical rubber balloons. The phenomenon is explained in terms of the nonideal rubber elasticity of balloons. The full phase diagram

  15. Specific binding of victorin to a 100-kDa protein from oats

    SciTech Connect

    Wolpert, T.J.; Macko, V. )

    1989-06-01

    Susceptibility of oats to victoria blight, caused by the fungus Cochliobolus victoriae, and sensitivity to the host-specific toxin victorin, produced by the fungus, are controlled by the dominant allele at the Vb locus. It has been postulated that the Vb locus encodes a toxin receptor, although direct evidence for such a receptor is not available. Recent studies on structure-activity relationships of the toxin established a methodology for producing {sup 125}I-labeled victorin. Electrophoretic analysis of proteins from isogenic susceptible and resistant oat genotypes following treatment of leaves with radiolabeled victorin showed that victorin binds in a covalent and a genotype-specific manner to a 100-kDa protein only in susceptible oat leaf slices. This in vivo binding was competitively displaced by reduced victorin, a nontoxic protective compound, and appeared to be correlated with biological activity. In vitro binding to the 100-kDa protein in leaf extracts showed several differences from in vivo binding. Binding was not genotype specific and required a reducing agent that was not required for in vivo binding. Differential centrifugation showed that the 100-kDa victorin binding protein was not a cytosolic protein but was enriched in a high-speed particulate fraction. The data support the hypothesis that the 100-kDa protein is the victorin receptor.

  16. A Case Study in Implementing Dependency-Based Grammars Made BOURDON, Lyne DA SYLVA, Michel GAGNON,

    E-print Network

    A Case Study in Implementing Dependency-Based Grammars Made BOURDON, Lyne DA SYLVA, Michel GAGNON grammar literature, led to inefficiency in the parser. By modifying the grammatical analysis in some cases,ldasylva,mgaguon,akharrat'sknoll,amaclachlan@machinasapiens.com http://www.machinasapiens.com Abstract In creating an English grammar checking software product, we

  17. Stress and Failure Analysis of Rapidly Rotating Asteroid (29075) 1950 DA

    NASA Astrophysics Data System (ADS)

    Hirabayashi, Masatoshi; Scheeres, Daniel J.

    2015-01-01

    Rozitis et al. recently reported that near-Earth asteroid (29075) 1950 DA, whose bulk density ranges from 1.0 g cm-3 to 2.4 g cm-3, is a rubble pile and requires a cohesive strength of at least 44-76 Pa to keep from failing due to its fast spin period. Since their technique for giving failure conditions required the averaged stress over the whole volume, it discarded information about the asteroid's failure mode and internal stress condition. This paper develops a finite element model and revisits the stress and failure analysis of 1950 DA. For the modeling, we do not consider material hardening and softening. Under the assumption of an associated flow rule and uniform material distribution, we identify the deformation process of 1950 DA when its constant cohesion reaches the lowest value that keeps its current shape. The results show that to avoid structural failure the internal core requires a cohesive strength of at least 75-85 Pa. It suggests that for the failure mode of this body, the internal core first fails structurally, followed by the surface region. This implies that if cohesion is constant over the whole volume, the equatorial ridge of 1950 DA results from a material flow going outward along the equatorial plane in the internal core, but not from a landslide as has been hypothesized. This has additional implications for the likely density of the interior of the body.

  18. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Standards for nitrogen oxides (NOX). 60... Steam Generating Units § 60.44Da Standards for nitrogen oxides (NOX). (a) Except as provided in... 50 percent or more of the total heat input to the combined cycle combustion turbine, the owner...

  19. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Standards for nitrogen oxides (NOX). 60... Steam Generating Units § 60.44Da Standards for nitrogen oxides (NOX). (a) Except as provided in... 50 percent or more of the total heat input to the combined cycle combustion turbine, the owner...

  20. In response to Dr. Jose AP da Silva: fall prevention with vitamin D clarifications needed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We agree with Dr. da Silva, and wish to clarify three issues raised by the recent IOM report concerning our 2009 meta-analysis on vitamin D and fall prevention. 1. The IOM questioned the inclusion of Broe et al., which did not pre-specify falls as a primary or secondary outcome. While this did viol...

  1. 40 CFR 60.43Da - Standards for sulfur dioxide (SO2).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Standards for sulfur dioxide (SO2). 60... Steam Generating Units § 60.43Da Standards for sulfur dioxide (SO2). (a) On and after the date on which... the percent reduction requirement is determined on a 24-hour basis. (d) Sulfur dioxide emissions...

  2. 40 CFR 60.43Da - Standards for sulfur dioxide (SO2).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false Standards for sulfur dioxide (SO2). 60... Steam Generating Units § 60.43Da Standards for sulfur dioxide (SO2). (a) On and after the date on which... the percent reduction requirement is determined on a 24-hour basis. (d) Sulfur dioxide emissions...

  3. 40 CFR 60.43Da - Standards for sulfur dioxide (SO2).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Standards for sulfur dioxide (SO2). 60... Steam Generating Units § 60.43Da Standards for sulfur dioxide (SO2). (a) On and after the date on which... the percent reduction requirement is determined on a 24-hour basis. (d) Sulfur dioxide emissions...

  4. 76 FR 14346 - Airworthiness Directives; Diamond Aircraft Industries GmbH Model DA 42 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Model DA 42 Airplanes...identified in this proposed AD, contact Diamond Aircraft Industries GmbH, N.A. Otto-Stra...43 2622 26780; e-mail: office@diamond-air.at; Internet:...

  5. 76 FR 31457 - Airworthiness Directives; Diamond Aircraft Industries GmbH Model DA 42 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-01

    ...2120-AA64 Airworthiness Directives; Diamond Aircraft Industries GmbH Model DA 42 Airplanes...information identified in this AD, contact Diamond Aircraft Industries GmbH, N.A. Otto-Stra...43 2622 26780; e- mail: office@diamond-air.at; Internet:...

  6. Projeto CityOn da Biodroid entre os finalistas dos Digital Communication

    E-print Network

    Instituto de Sistemas e Robotica

    finalistas na categoria Best Corporate Games, o jogo da Biodroid coloca o jogador no papel de gestor dos jovens e jovens adultos que utilizam com frequência a Internet e os jogos online. Apresentando-se pela gratuitamente no site oficial do jogo, e está dispoível em português, inglês e espanhol. Ainda não há

  7. The bow shocks and upstream waves of Venus and Mars D.A. Brain *

    E-print Network

    California at Berkeley, University of

    The bow shocks and upstream waves of Venus and Mars D.A. Brain * LASP/University of Colorado; accepted 14 May 2003 Abstract Because they both lack measurable magnetic fields, Venus and Mars are often waves are observed. In many respects the collisionless shocks at Venus and Mars are quite different

  8. A Integracao de Ensino das Ciencias da Saude (An Integrated Medical Education Program [in Brazil]).

    ERIC Educational Resources Information Center

    Pourchet-Campos, M. A.; Guimaraes Junior, Paulino

    At the Sixth Annual Reunion of the Brazilian Association of Medical Schools (VI Reuniao Anual da Associacao Brasileira de Escolas Medicas) leaders in the Brazilian medical profession proposed an integrated educational program for training students in the fields of medicine and public health. Under Brazil's present system of education, all…

  9. A Generic Multilevel Multiplying D/A Converter for Pipelined ADCs

    E-print Network

    Moon, Un-Ku

    A Generic Multilevel Multiplying D/A Converter for Pipelined ADCs Vivek Sharma, Un-Ku Moon, Gabor C.Sharma@austriamicrosystems.com, moon@ece.orst.edu, temes@ece.orst.edu Abstract--State-of-art implementations of pipelined ADCs can only stage. Previous research has shown the importance of choosing the number of levels m and also suggested

  10. 76 FR 19903 - Special Conditions: Diamond Aircraft Industry Model DA-40NG; Diesel Cycle Engine

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ... Conditions: Diamond Aircraft Industry Model DA-40NG; Diesel Cycle Engine AGENCY: Federal Aviation... E4 aircraft diesel engine (ADE) using turbine (jet) fuel. This airplane will have a novel or unusual design feature(s) associated with the installation of a diesel cycle engine utilizing turbine (jet)...

  11. PanDA Beyond ATLAS : A Scalable Workload Management System For Data Intensive Science

    E-print Network

    Borodin, M; The ATLAS collaboration; Jha, S; Golubkov, D; Klimentov, A; Maeno, T; Nilsson, P; Oleynik, D; Panitkin, S; Petrosyan, A; Schovancova, J; Vaniachine, A; Wenaus, T

    2014-01-01

    The LHC experiments are today at the leading edge of large scale distributed data-intensive computational science. The LHC's ATLAS experiment processes data volumes which are particularly extreme, over 140 PB to date, distributed worldwide at over of 120 sites. An important element in the success of the exciting physics results from ATLAS is the highly scalable integrated workflow and dataflow management afforded by the PanDA workload management system, used for all the distributed computing needs of the experiment. The PanDA design is not experiment specific and PanDA is now being extended to support other data intensive scientific applications. PanDA was cited as an example of "a high performance, fault tolerant software for fast, scalable access to data repositories of many kinds" during the "Big Data Research and Development Initiative" announcement, a 200 million USD U.S. government investment in tools to handle huge volumes of digital data needed to spur science and engineering discoveries. In this talk...

  12. Analysis of Chandra-LETG spectra of two DA white dwarfs and a PG 1159 star

    E-print Network

    Barnstedt, Jürgen

    of hot DAs with Teff > 30000K, H is almost completely ionized and the opacity strongly reduced. X white dwarfs with Teff > 60000K were detected at all [1], among these the class of the metal poor DA WDs Vir instability strip in the HRD. The pulsations depend on the chemical composition, logg, and Teff

  13. The Validity of the Autism Spectrum Disorders-Diagnosis for Intellectually Disabled Adults (ASD-DA)

    ERIC Educational Resources Information Center

    Matson, Johnny L.; Wilkins, Jonathan; Boisjoli, Jessica A.; Smith, Kimberly R.

    2008-01-01

    Psychologists interviewed direct-care staff using a battery of assessment measures including the autism spectrum disorders-diagnosis for intellectually disabled adults (ASD-DA), the Diagnostic Assessment for the Severely Handicapped-II (DASH-II), the Matson Evaluation of Social Skills for Individuals with Severe Retardation (MESSIER), the…

  14. 76 FR 72087 - Special Conditions: Diamond Aircraft Industries, Model DA-40NG; Electronic Engine Control (EEC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-22

    ...unusual design features on one model of airplane. It is not a rule...Diamond Aircraft Industry GmbH model DA-40NG with the installation of the Austro Engine GmbH model E4 aircraft diesel engine...or malfunction or probable combinations of failures of Electronic...

  15. 40 CFR 60.40Da - Applicability and designation of affected facility.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... combination with any other fuel) in the combustion turbine engine and associated heat recovery steam generator... Performance for Electric Utility Steam Generating Units § 60.40Da Applicability and designation of affected... subpart applies is each electric utility steam generating unit: (1) That is capable of combusting...

  16. 40 CFR 60.40Da - Applicability and designation of affected facility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... combination with any other fuel) in the combustion turbine engine and associated heat recovery steam generator... Performance for Electric Utility Steam Generating Units § 60.40Da Applicability and designation of affected... subpart applies is each electric utility steam generating unit: (1) That is capable of combusting...

  17. 76 FR 72087 - Special Conditions: Diamond Aircraft Industries, Model DA-40NG; Electronic Engine Control (EEC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-22

    ...These special conditions are issued for the Diamond Aircraft Industries, Model DA-40NG airplane. This airplane will have a novel or unusual design feature(s) associated with an electronic engine control (EEC) also known as a Full authority Digital Engine Control (FADEC). The applicable airworthiness regulations do not contain adequate or appropriate safety standards for this design feature.......

  18. Orthogonality Does Not Imply Asymptotic Normality DA Freedman Statistics 215 October 2007

    E-print Network

    Freedman, David A.

    . With rapidly increasing block length, D2 n/n oscillates between 0+ and 2-. So Sn/ n isn't asymptoticallyOrthogonality Does Not Imply Asymptotic Normality DA Freedman Statistics 215 October 2007 Consider to normalizing regression statistics by ^. The punchline: the usual asymptotics need not hold for the OLS

  19. Como os Alunos do Ensino Médio da Rede Estadual de São Paulo obtém Conhecimentos Astronômicos?

    NASA Astrophysics Data System (ADS)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2005-08-01

    Atualmente vivencia-se um mundo globalizado onde os computadores e a internet permitiram um acesso rápido e seguro a todo tipo de informação e conhecimento. O presente trabalho visa analisar a maneira pela qual alunos de segundo grau da rede estadual da cidade de São Paulo obtiveram, caso tenham, conhecimentos básicos de astronomia quanto aos fenômenos celestes que os rodeiam, tais como a sucessão dos dias e das estações do ano, além de questioná~los sobre fatos genéricos tais como: o que vem a ser o Sol, o Big Bang, o que ocasionou a extinção dos dinossauros. Para tanto foi elaborado um formulário constando de questões de múltipla escolha, o qual foi aplicado no primeiro colegial diurno da Escola Estadual Guilherme de Almeida. Num espaço amostral de 44 alunos constatou-se que 41% dos alunos adquiriram seus conhecimentos astronômicos na escola e 59% através da mídia em geral. Neste mesmo espaço amostral apenas 11% dos alunos usaram computadores na escola, 41% na residência, 5% no trabalho e 43% não utilizaram. O presente estudo revelou também que para 50% dos alunos o professor jamais utilizou um programa de computador a respeito de astronomia ou fez alguma apresentação sobre o tema. Embora em sua fase inicial este estudo revela claramente que a maioria dos alunos não obtém na escola seus conhecimentos astronômicos, estes provém de fontes não especificamente didático-pedagógicas tais como filmes e revistas populares que não raramente geram conhecimentos incompletos e em muitos casos inclusive falhos.

  20. STRESS AND FAILURE ANALYSIS OF RAPIDLY ROTATING ASTEROID (29075) 1950 DA

    SciTech Connect

    Hirabayashi, Masatoshi; Scheeres, Daniel J.

    2015-01-01

    Rozitis et al. recently reported that near-Earth asteroid (29075) 1950 DA, whose bulk density ranges from 1.0 g cm{sup –3} to 2.4 g cm{sup –3}, is a rubble pile and requires a cohesive strength of at least 44-76 Pa to keep from failing due to its fast spin period. Since their technique for giving failure conditions required the averaged stress over the whole volume, it discarded information about the asteroid's failure mode and internal stress condition. This paper develops a finite element model and revisits the stress and failure analysis of 1950 DA. For the modeling, we do not consider material hardening and softening. Under the assumption of an associated flow rule and uniform material distribution, we identify the deformation process of 1950 DA when its constant cohesion reaches the lowest value that keeps its current shape. The results show that to avoid structural failure the internal core requires a cohesive strength of at least 75-85 Pa. It suggests that for the failure mode of this body, the internal core first fails structurally, followed by the surface region. This implies that if cohesion is constant over the whole volume, the equatorial ridge of 1950 DA results from a material flow going outward along the equatorial plane in the internal core, but not from a landslide as has been hypothesized. This has additional implications for the likely density of the interior of the body.

  1. Transparency of Vocational Qualifications: The Leonardo da Vinci Approach. CEDEFOP Panorama Series.

    ERIC Educational Resources Information Center

    Bjornavold, Jens; Pettersson, Sten

    This report gives an overview of the situation of transparency of vocational qualifications by presenting measures introduced at the European Community level and by drawing attention to projects within the Leonardo da Vinci Program dealing with the issue. A 16-page executive summary appears first. Chapter 1 provides general background and aims.…

  2. Leonardo da Vinci, One Year on...a Different Look at Vocational Training in Europe.

    ERIC Educational Resources Information Center

    Le Magazine, 1996

    1996-01-01

    Discusses the success of the Leonardo da Vinci program, a European laboratory of innovation in vocational training, a priority focus of investment in human resources and intelligence, and a way to mobilize innovative forces beyond national boundaries. Trends identified by the program focus on new information and communication technologies. (JOW)

  3. Employee Drug and Alcohol Abuse Policy #CofC.HR.DA.03 Revised 12/2001

    E-print Network

    Kunkle, Tom

    Policy Employee Drug and Alcohol Abuse Policy #CofC.HR.DA.03 Revised 12/2001 The Drug-Free Schools requires them to have a Commercial Driver's License. The policy below, Employee Drug and Alcohol Abuse committed to having a campus that is free of the illegal or abusive use of drugs and alcohol. In keeping

  4. Application of Wildland Fire Assessments1 Michael A. da Luz,2

    E-print Network

    sensitivity, goals, and priorities. Ranking can be based on quantifiable and detailed data if it is available that result in similar fire behavior characteristics. In our experience, we used vegetative data, reduced themApplication of Wildland Fire Assessments1 Michael A. da Luz,2 William S. Wallis3 Abstract Wildland

  5. Understanding and Interpreting Japanese NP1 "wa" NP2 "da" Sentences: Mechanism and Contextual Factors

    ERIC Educational Resources Information Center

    Yoshida, Megumi

    2013-01-01

    This dissertation investigates the contextual factors that affect the understanding and interpretation of one Japanese topicalized construction, NP[subscript 1] wa NP[subscript 2] da sentences, by native speakers of Japanese. The construction allows two possibilities in the relation between the NP[subscript 1] and the NP[subscript 2]. When the two…

  6. Vo1. nI. No. 1 CHARLES DA.RWI~

    E-print Network

    Vo1. nI. No. 1 JUN 101930 JUNE 1930 ~. S-s 20 Cehts CHARLES DA.RWI~ #12;EVOLUTION e5\\ Journal of P'in at the recent dedit:tdion of Darwin's old hOllle, Down Housc, as a public nlOl1UllIent. E\\,OLUTIOl'; joins

  7. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  8. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  9. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  10. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  11. 32 CFR 644.512 - DA-SBA joint set-aside determination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Standing Timber, Crops, and Embedded Gravel, Sand and Stone § 644.512 DA-SBA joint set-aside determination. Section 15 of the Small Business Act (15 U.S.C....

  12. Brominated and radioiodinated derivatives of methylphenidate (MP): Potential imaging agents for the dopamine (DA) transporter

    SciTech Connect

    Pan, D.; Gatley, S.J.; Dewey, S.L.

    1994-05-01

    MP (Ritalin) is a psychomotor stimulant used in the treatment of attention-deficit hyperactivity disorder. The therapeutic properties of MP are thought to be mediated by its binding to a site on the DA transporter, resulting in inhibition of DA reuptake and enhanced levels of synaptic dopamine. MP also inhibits reuptake of norepinephrine (NE) in vitro. MP has two chiral centers, but its pharmacological activity is believed due solely to the d-threo isomer. We have found that d,l-threo-C-11 MP has favorable properties for PET studies, and therefore examined the effects of incorporating halogen atoms into the phenyl ring of MP, with a view to preparing C-11 and I-123 MP analogs as potential PET/SPECT tracers. We synthesized the 2-, 3- and 4-bromo MP analogs from the corresponding bromophenylacetonitriles by modification of the original synthesis of MP. In in vitro binding assays all three d,l-threo bromo compounds had higher affinities than MP for DA transporter sites labeled with tritiated WIN 35,428 (3->4-, 2->MP). They also showed high activity with NE reuptake sites labeled with tritiated nisoxetine. They were active in vivo as demonstrated by inhibition of heart uptake of tritiated NE in the mouse, and elevation of striatal extracellular DA (microdialysis) and stimulation of locomotor activity in the rat.

  13. 99129-5/2002-DR/SC A fartura da iniciao cientfica

    E-print Network

    Floeter, Sergio Ricardo

    Universidade Federal de Santa Catarina - Novembro de 2009 - Nº 406 Um novo Magnífico p. 14 UFFS Parceiro da ciência p (Jornalista) Margareth Rossi (Jornalista) Maria Luiza de Oliveira Gil (Bolsista) Natália Izidoro (Bolsista as ciências duras. É preciso mudar essa visão. (Maria Lúcia de Barros Camargo, pró-reito- ra de Pós

  14. DNA binding properties of a 110 kDa nucleolar protein.

    PubMed Central

    Sapp, M; Knippers, R; Richter, A

    1986-01-01

    A single strand specific DNA binding protein was purified to homogeneity from calf thymus nucleoprotein. The monomeric protein is elongated in shape and has a molecular mass of 110 kDa. Since immunocytochemistry revealed that the protein is predominantly located in the nucleolus we refer to it as the 110 kDa nucleolar protein. The protein binds not only to single stranded DNA but also to single stranded RNA, including homopolymeric synthetic RNA. We have used the single stranded DNA binding properties of the 110 kDa protein in model studies to investigate its effects on the configuration of nucleic acid. Our results are: only 50-55 protein molecules are sufficient to saturate all binding sites on the 6408 nucleotides of phage fd DNA; protein binding cause a compaction of single stranded DNA; large nucleoprotein aggregates are formed in the presence of divalent cations; this is due to protein-protein interactions which occur at moderately high concentrations of magnesium-, calcium or manganese ions; the protein induces the reassociation of complementary nucleic acid sequences. We speculate that the 110 kDa protein performs similar reactions in vivo and may have a function related to the processing and packaging of preribosomal RNA. Images PMID:3763392

  15. Roles of upper-level processes in tropical cyclogenesis Da-Lin Zhang1

    E-print Network

    Zhang, Da-Lin

    Roles of upper-level processes in tropical cyclogenesis Da-Lin Zhang1 and Lin Zhu1 Received 16 July and prediction of TCG. Citation: Zhang, D.-L., and L. Zhu (2012), Roles of upper-level processes in tropical and Zhang, 2008], and mesoscale convective systems (MCSs) [Zhang and Bao, 1996a, 1996b; Zhang et al., 2011

  16. The Harvard University daVinci Center Initiative for Physical Biology

    E-print Network

    #12;The Harvard University daVinci Center Initiative for Physical Biology: Viewing Living Systems rationale. For the past 50-100 years, biology at the molecular and cellular levels has been viewed primarily) on the basis of their shared belief that the next round of fundamental advances in the life sciences

  17. MATERNAL ATRAZINE (ATR) ALTERS HYPOTHALAMIC DOPAMINE (HYP-DA) AND SERUM PROLACTIN (SPRL) IN MALE PUPS

    EPA Science Inventory

    Maternal Atrazine (ATR) alters hypothalamic dopamine (HYP-DA) and serum prolactin (sPRL) in male pups. 1Christopher Langdale, 2Tammy Stoker and 2Ralph Cooper. 1 Dept. of Cell Biology, North Carolina State University College of Veterinary Medicine, Raleigh, NC. 2 Endocrinology ...

  18. MODELING OF THE "PLAN DA MATTUN" ARCHAEOLOGICAL SITE USING A COMBINATION OF DIFFERENT SENSORS

    E-print Network

    Schindler, Konrad

    . The larger boulders feature a resolution of 1 cm and a relative accuracy of 0.5 cm. The 3D data is to be used, close range, DEM/DTM, laser scanning, measurement, reconstruction, visualization ABSTRACT: Plan da surveying techniques in order to cover all objects of interest. Therefore the digital terrain model

  19. La verit`a matematica da Kant a Godel Alessandro Berarducci

    E-print Network

    Berarducci, Alessandro

    pensatore poco pi`u di un secolo prima. Immanuel Kant 1724-1804 "La rappresentazione dello spazio non puLa verit`a matematica da Kant a G¨odel Alessandro Berarducci Pisa, 15 Marzo 2010 Questa `e la evidentemente essa non `e una scienza sperimentale? Kant 1787. L'intuizione Sentiamo cosa diceva un altro grande

  20. Upstream urbanization exacerbates urban heat island effects Da-Lin Zhang,1

    E-print Network

    Zhang, Da-Lin

    Upstream urbanization exacerbates urban heat island effects Da-Lin Zhang,1 Yi-Xuan Shou,1; published 19 December 2009. [1] Urban Heat Island (UHI) effects adversely impact weather, air quality find that upstream urbanization exacerbates UHI effects and that meteorological consequences of extra-urban

  1. Quantification of Translocator Protein (18 kDa) in the Human Brain with PET

    E-print Network

    Pike, Victor W.

    benzodiazepine receptor, is upregulated on activated microglia and macrophages and is, thus, a biomarker (TSPO) (18kDa), formerly called the peripheral benzodiazepine receptor, is a mitochondrial proteinC-(R)-PK 11195 have been used for in vivo imaging of peripheral benzodiazepine receptors (PBRs

  2. English languagE Program WinniPEg, manitoba, CanaDa

    E-print Network

    Martin, Jeff

    -focused, job ready and general interest courses, as well as, certificate and diploma programs aimedEnglish languagE Program WinniPEg, manitoba, CanaDa #12;thE univErsity of WinniPEg English language Program The University of Winnipeg English Language Program welcomes more than 450 students from more than

  3. An Enhanced Wiki for Requirements Engineering David de Almeida Ferreira, and Alberto Rodrigues da Silva

    E-print Network

    da Silva, Alberto Rodrigues

    An Enhanced Wiki for Requirements Engineering David de Almeida Ferreira, and Alberto Rodrigues da of an enhanced Wiki for dealing with Requirements Engineering aspects, according to a CSCW approach. Moreover, we discuss the benefits of this Wiki- based solution in the broader context of ProjectIT initiative, and how

  4. Global prediction of dA and d2 O evaporation slopes for lakes

    E-print Network

    Edwards, Thomas W.D.

    -based isotope measurements of vapor, surface water, and soil water and as a diagnostic tool for more complexGlobal prediction of dA and d2 H-d18 O evaporation slopes for lakes and soil water accounting slope of continental lakes and shallow soil water undergoing natural evaporation are predicted

  5. XXIII Congresso Brasileiro em Engenharia Biomdica XXIII CBEB ANLISE MULTIDIMENSIONAL DA FADIGA MUSCULAR POR MEIO DE

    E-print Network

    Carvalho, João Luiz

    FADIGA MUSCULAR POR MEIO DE ELETROMIOGRAFIA DE SUPERFÍCIE DE ALTA DENSIDADE G. M. Q. Mendonça1 , F. A fadiga muscular, por meio de mapas topológicos (no plano espacial) e regressão linear (no eixo do tempo trabalho propõe a avaliação da fatigabilidade em três momentos -- início, meio e fim -- do esforço. Esta

  6. 1/4 XXII CBEB 2010 MEDIO DA VARIABILIDADE DO VOLUME SISTLICO POR MEIO DE

    E-print Network

    Carvalho, João Luiz

    1/4 XXII CBEB 2010 MEDIÇÃO DA VARIABILIDADE DO VOLUME SISTÓLICO POR MEIO DE RESSONÂNCIA MAGNÉTICA do débito cardíaco por meio de ressonância magnética (RM) de fluxo [2,3]. Embora resultados técnica para medição não invasiva do volume sistólico batimento a batimento por meio de RM de fluxo

  7. Characterisation of the 5 kDa growth hormone isoform GERARD SUCH-SANMARTIN1

    E-print Network

    Pompeu Fabra, Universitat

    phase synthesis, limited proteolysis Abbreviations: GH, human growth hormone; T2DM, type 2 diabetesCharacterisation of the 5 kDa growth hormone isoform GERARD SUCH-SANMARTI´N1 , JAUME BOSCH1 , JORDI-terminal fragment of 43 amino acids of human growth hormone (GH) shows a specific and significant in-vivo insulin

  8. An Architecture for Motion Capture Based Animation Fernando Wagner Serpa Vieira da Silva 1;2

    E-print Network

    de Figueiredo, Luiz Henrique

    An Architecture for Motion Capture Based Animation Fernando Wagner Serpa Vieira da Silva 1;2 Luiz animation systems, that works with several data formats and uses the building block paradigm for motion of the animation main elements. A prototype system has been implemented, based on the presented concepts, and its

  9. An Architecture for Motion Capture Based Animation FERNANDO WAGNER DA SILVA1;2

    E-print Network

    de Figueiredo, Luiz Henrique

    An Architecture for Motion Capture Based Animation FERNANDO WAGNER DA SILVA1;2 LUIZ VELHO1 PAULO Abstract. This paper proposes an architecture for motion capture based animation systems, which works interface is proposed to perform an intuitive visualization of the animation main elements. A prototype

  10. An Architecture for Motion Capture Based Animation Fernando Wagner da Silva 1,2

    E-print Network

    de Figueiredo, Luiz Henrique

    An Architecture for Motion Capture Based Animation Fernando Wagner da Silva 1,2 Luiz Velho 1 Paulo Postal 68511 Abstract. This paper proposes an architecture for motion capture based animation systems operations. Also, a user interface is proposed to perform an intuitive visualization of the animation main

  11. An Architecture for Motion Capture Based Animation FERNANDO WAGNER DA SILVA 1;2

    E-print Network

    de Figueiredo, Luiz Henrique

    An Architecture for Motion Capture Based Animation FERNANDO WAGNER DA SILVA 1;2 LUIZ VELHO 1 PAULO 68511 Abstract. This paper proposes an architecture for motion capture based animation systems, which. Also, a user interface is proposed to perform an intuitive visualization of the animation main elements

  12. Next Generation PanDA Pilot for ATLAS and Other Experiments

    NASA Astrophysics Data System (ADS)

    Nilsson, P.; Barreiro Megino, F.; Caballero Bejar, J.; De, K.; Hover, J.; Love, P.; Maeno, T.; Medrano Llamas, R.; Walker, R.; Wenaus, T.; Atlas Collaboration

    2014-06-01

    The Production and Distributed Analysis system (PanDA) has been in use in the ATLAS Experiment since 2005. It uses a sophisticated pilot system to execute submitted jobs on the worker nodes. While originally designed for ATLAS, the PanDA Pilot has recently been refactored to facilitate use outside of ATLAS. Experiments are now handled as plug-ins such that a new PanDA Pilot user only has to implement a set of prototyped methods in the plug-in classes, and provide a script that configures and runs the experiment-specific payload. We will give an overview of the Next Generation PanDA Pilot system and will present major features and recent improvements including live user payload debugging, data access via the Federated XRootD system, stage-out to alternative storage elements, support for the new ATLAS DDM system (Rucio), and an improved integration with glExec, as well as a description of the experiment-specific plug-in classes. The performance of the pilot system in processing LHC data on the OSG, LCG and Nordugrid infrastructures used by ATLAS will also be presented. We will describe plans for future development on the time scale of the next few years.

  13. The next generation of the ATLAS PanDA Monitoring System

    E-print Network

    Schovancova, J; The ATLAS collaboration; Klimentov, A; Love, P; Potekhin, M; Wenaus, T

    2014-01-01

    For many years the PanDA Workload Management System has been the basis for distributed production and analysis for the ATLAS experiment at the LHC. Since the start of data taking PanDA usage has ramped up steadily, with up to 1M completed jobs/day in 2013. The associated monitoring data volume has been rising as well, to levels that present a new set of challenges in the areas of database scalability and monitoring system performance and efficiency. Outside of ATLAS, the PanDA system is also being used in projects like AMS, LSST and a few others. It currently undergoes a significant redesign, both of the core server components responsible for workload management, brokerage and data access, and of the monitoring part, which is critically important for efficient execution of the workflow in a way that’s transparent to the user and also provides an effective set of tools for operational support. The new generation of the PanDA Monitoring Service is designed based on a proven, scalable, industry-standard Web Fr...

  14. Assessments of the economic impacts of natural hazards in Albania: application of DaLA methodology.

    NASA Astrophysics Data System (ADS)

    Massabo, Marco; Toto, Emanuela; Deda, Miranda; Prenci, Shemsi; Dhima, Maksimiljan

    2015-04-01

    Disaster loss datasets are built using economic assessments done by different parties and using different approaches which are in many cases inconsistent. This is observed in more than 75% of the Alabanian records with missing economic evaluations. To assess the economic impact of disasters at all scales in Global Assessment Report on Disaster Risk Reduction 2011 and 2013 has used the DaLA methodology that takes advantage of a common and homogeneous set of quantitative physical damage indicators contained in the disaster databases. These have to be taken as the lower bound of the damage, which in general is higher. The UN-ECLAC DaLA Methodology takes into account in its assessments the overall status of economy of the affected country. It uses the national accounts and statistics of the country government as baseline data to assess damage and loss. It also factors in the impact of disasters on individual livelihoods and incomes to fully define the needs for recovery and reconstruction. Similarly to national disaster loss databases DaLA assessments have a national level of observation and data produced at sub-national resolution, resulting in highly detailed and accurate data sets. In 2013 in Albania was implemented a collection of disaster losses based on Desinventar. We applied the DaLa methodology to the Albanian database of impacts of natural disasters.

  15. Universit di Pisa Scuola di dottorato in Ingegneria "Leonardo da Vinci"

    E-print Network

    Meini, Beatrice

    ) dal titolo: Displacement-Based Seismic Design of Structures Sommario. Il corso si propone di-BASED SEISMIC DESIGN OF STRUCTURES, di M.J.N. Priesltey, G.M. Calvi e M.J. Kowalsky, pubblicato nel 2007 da IUSS

  16. Characterization of new 18-kDa IgE-binding proteins in beer.

    PubMed

    Hiemori, Miki; Eguchi, Yuka; Kimoto, Masumi; Yamasita, Hiromi; Takahashi, Kyoko; Takahashi, Kiyoshi; Tsuji, Hideaki

    2008-04-01

    The IgE-binding proteins in beer were examined by immunoblotting analysis with sera of patients sensitive to beer. Several proteins were immunoblotted with the sera, and among these, 18-kDa proteins were identified as new IgE-binding proteins in beer. Perhaps they originated from barley as a raw material. PMID:18391472

  17. 20/10/2012 | NOTAS Professora recebe prmio cientfico da Unesco

    E-print Network

    Barbosa, Marcia C. B.

    /10/2012 do Jornal Cruzeiro do Sul, na página 008 do caderno B - o conteúdo da edição impressa na internet é liberado, porém responderá por crime ambiental. 08 NOV 2012 | Sorocaba SP SOROCABA REGIÃO BRASIL EXTERIOR internet, manifestar-se dessa forma é o mesmo que gritar; 8. Este espaço é destinado somente a comentários

  18. 40 CFR 60.44Da - Standard for nitrogen oxides (NOX).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Steam Generating Units for Which Construction is Commenced After September 18, 1978 § 60.44Da Standard... average basis. (e) Except for an IGCC electric utility steam generating unit meeting the requirements of... under § 60.8, whichever date comes first, the owner or operator of an IGCC electric utility...

  19. 40 CFR 60.50Da - Compliance determination procedures and methods.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Electric Utility Steam Generating Units § 60.50Da Compliance determination procedures and methods. (a) In... calculations from the gas turbine used in Method 19 of appendix A-7 of this part are determined when the gas turbine is performance tested under subpart GG of this part. The potential uncontrolled PM emission...

  20. 40 CFR 60.50Da - Compliance determination procedures and methods.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Electric Utility Steam Generating Units § 60.50Da Compliance determination procedures and methods. (a) In... operator of an electric utility combined cycle gas turbine that does not meet the definition of an IGCC... of this part. The SO2 and NOX emission rates calculations from the gas turbine used in Method 19...

  1. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Steam Generating Units § 60.44Da Standards for nitrogen oxides (NOX). (a) Except as provided in..., whichever date comes first, the owner or operator of an IGCC electric utility steam generating unit subject... 50 percent or more of the total heat input to the combined cycle combustion turbine, the owner...

  2. 40 CFR 60.44Da - Standard for nitrogen oxides (NOX).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Steam Generating Units for Which Construction is Commenced After September 18, 1978 § 60.44Da Standard... average basis. (e) Except for an IGCC electric utility steam generating unit meeting the requirements of... under § 60.8, whichever date comes first, the owner or operator of an IGCC electric utility...

  3. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Steam Generating Units § 60.44Da Standards for nitrogen oxides (NOX). (a) Except as provided in..., whichever date comes first, the owner or operator of an IGCC electric utility steam generating unit subject... 50 percent or more of the total heat input to the combined cycle combustion turbine, the owner...

  4. 40 CFR 60.50Da - Compliance determination procedures and methods.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Electric Utility Steam Generating Units § 60.50Da Compliance determination procedures and methods. (a) In... operator of an electric utility combined cycle gas turbine that does not meet the definition of an IGCC... of this part. The SO2 and NOX emission rates calculations from the gas turbine used in Method 19...

  5. 40 CFR 60.44Da - Standards for nitrogen oxides (NOX).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Steam Generating Units § 60.44Da Standards for nitrogen oxides (NOX). (a) Except as provided in..., whichever date comes first, the owner or operator of an IGCC electric utility steam generating unit subject... 50 percent or more of the total heat input to the combined cycle combustion turbine, the owner...

  6. Computerized Dynamic Assessment (C-DA): Diagnosing L2 Development According to Learner Responsiveness to Mediation

    ERIC Educational Resources Information Center

    Poehner, Matthew E.; Zhang, Jie; Lu, Xiaofei

    2015-01-01

    Dynamic assessment (DA) derives from the sociocultural theory of mind as elaborated by Russian psychologist L. S. Vygotsky. By offering mediation when individuals experience difficulties and carefully tracing their responsiveness, Vygotsky (1998) proposed that diagnoses may uncover abilities that have fully formed as well as those still in the…

  7. Notes & Tips Utilities for quantifying separation in PCA/PLS-DA scores plots

    E-print Network

    Powers, Robert

    Notes & Tips Utilities for quantifying separation in PCA/PLS-DA scores plots Bradley Worley, Steven and chemo- metric analyses involving these low-dimensional scores plots necessitates the use of quantitative in scores plots through dendrograms employing both nonparametric and parametric hypothesis testing to assess

  8. 11 CFR 111.15 - Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)). 111.15...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4))....

  9. 11 CFR 111.15 - Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)). 111.15...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4))....

  10. 11 CFR 111.12 - Subpoenas and subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)). 111.12...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4))....

  11. 11 CFR 111.15 - Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)). 111.15...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4))....

  12. 11 CFR 111.13 - Service of subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)). 111.13...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4))....

  13. 11 CFR 111.12 - Subpoenas and subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)). 111.12...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4))....

  14. 11 CFR 111.13 - Service of subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)). 111.13...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4))....

  15. 11 CFR 111.15 - Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)). 111.15...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4))....

  16. 11 CFR 111.12 - Subpoenas and subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)). 111.12...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4))....

  17. 11 CFR 111.13 - Service of subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)). 111.13...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4))....

  18. 11 CFR 111.12 - Subpoenas and subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)). 111.12...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4))....

  19. 11 CFR 111.15 - Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...Motions to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4)). 111.15...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...to quash or modify a subpoena (2 U.S.C. 437d(a) (3), (4))....

  20. 11 CFR 111.13 - Service of subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)). 111.13...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4))....

  1. 11 CFR 111.13 - Service of subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4)). 111.13...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas, orders and notifications (2 U.S.C. 437d(a) (3), (4))....

  2. 11 CFR 111.12 - Subpoenas and subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4)). 111.12...GENERAL COMPLIANCE PROCEDURE (2 U.S.C. 437g, 437d(a)) Enforcement § 111...subpoenas duces tecum; depositions (2 U.S.C. 437d(a) (3), (4))....

  3. PanDA Pilot Submission using Condor-G: Experience and Improvements

    SciTech Connect

    Zhao X.; Hover John; Wlodek Tomasz; Wenaus Torre; Frey Jaime; Tannenbaum Todd; Livny Miron

    2011-01-01

    PanDA (Production and Distributed Analysis) is the workload management system of the ATLAS experiment, used to run managed production and user analysis jobs on the grid. As a late-binding, pilot-based system, the maintenance of a smooth and steady stream of pilot jobs to all grid sites is critical for PanDA operation. The ATLAS Computing Facility (ACF) at BNL, as the ATLAS Tier1 center in the US, operates the pilot submission systems for the US. This is done using the PanDA 'AutoPilot' scheduler component which submits pilot jobs via Condor-G, a grid job scheduling system developed at the University of Wisconsin-Madison. In this paper, we discuss the operation and performance of the Condor-G pilot submission at BNL, with emphasis on the challenges and issues encountered in the real grid production environment. With the close collaboration of Condor and PanDA teams, the scalability and stability of the overall system has been greatly improved over the last year. We review improvements made to Condor-G resulting from this collaboration, including isolation of site-based issues by running a separate Gridmanager for each remote site, introduction of the 'Nonessential' job attribute to allow Condor to optimize its behavior for the specific character of pilot jobs, better understanding and handling of the Gridmonitor process, as well as better scheduling in the PanDA pilot scheduler component. We will also cover the monitoring of the health of the system.

  4. Estudo exaustivo e sistemático de erros nas provas da olimpíada brasileira de astronomia - resultados preliminares

    NASA Astrophysics Data System (ADS)

    Oliveira, F. S.; Canalle, J. B. G.; Villas da Rocha, J. F.

    2003-08-01

    A Olimpíada Brasileira de Astronomia (OBA) contou, em sua quinta edição, com a participação de mais de 60 mil alunos dos ensinos fundamental e médio de praticamente todo o território nacional. Uma das formas de controle que a sua coordenação nacional possui sobre a correção, levada a cabo pelos professores que as aplicaram, é a do envio, por parte destes professores, das 10 melhores provas de cada um dos três níveis nos quais a Olimpíada é realizada. Assim, e dado ao caráter discursivo das provas da Olimpíada, a sua coordenação nacional dispõe de um vasto acervo sobre as concepções, certas ou erradas, dos alunos que dela participaram. Este conjunto de dados jamais fora explorado até o presente trabalho que pretende ser, neste sentido, inaugural. Nas provas dos níveis I e II da V OBA, que abrangem todo o conjunto do ensino fundamental, uma das questões versava sobre a noção que os alunos tinham sobre como os habitantes da Terra situam-se sobre sua superfície. Fizemos um estudo sistemático das respostas a esta questão. Primeiramente, todas as modalidades de erros foram levantadas; em seguida, realizamos uma distribuição por idade tanto do índice de acerto como da ocorrência e da distribuição de cada erro. Como resultado, obtivemos que, em ambos os níveis: 1) as concepções errôneas não se apresentam distribuídas aleatoriamente; 2) há uma concentração no tipo de erro apresentado; 3) há uma tendência de progressivo acerto com relação à idade quando os dados são considerados em termos nacionais; 4) esta tendência nacional é fraca ou mesmo não é verificada em alguns dos estados com maior patamar de acerto.

  5. Automatic localization of the da Vinci surgical instrument tips in 3-D transrectal ultrasound.

    PubMed

    Mohareri, Omid; Ramezani, Mahdi; Adebar, Troy K; Abolmaesumi, Purang; Salcudean, Septimiu E

    2013-09-01

    Robot-assisted laparoscopic radical prostatectomy (RALRP) using the da Vinci surgical system is the current state-of-the-art treatment option for clinically confined prostate cancer. Given the limited field of view of the surgical site in RALRP, several groups have proposed the integration of transrectal ultrasound (TRUS) imaging in the surgical workflow to assist with accurate resection of the prostate and the sparing of the neurovascular bundles (NVBs). We previously introduced a robotic TRUS manipulator and a method for automatically tracking da Vinci surgical instruments with the TRUS imaging plane, in order to facilitate the integration of intraoperative TRUS in RALRP. Rapid and automatic registration of the kinematic frames of the da Vinci surgical system and the robotic TRUS probe manipulator is a critical component of the instrument tracking system. In this paper, we propose a fully automatic registration technique based on automatic 3-D TRUS localization of robot instrument tips pressed against the air-tissue boundary anterior to the prostate. The detection approach uses a multiscale filtering technique to identify and localize surgical instrument tips in the TRUS volume, and could also be used to detect other surface fiducials in 3-D ultrasound. Experiments have been performed using a tissue phantom and two ex vivo tissue samples to show the feasibility of the proposed methods. Also, an initial in vivo evaluation of the system has been carried out on a live anaesthetized dog with a da Vinci Si surgical system and a target registration error (defined as the root mean square distance of corresponding points after registration) of 2.68 mm has been achieved. Results show this method's accuracy and consistency for automatic registration of TRUS images to the da Vinci surgical system. PMID:23674418

  6. Effects of acute amphetamine (AMPH) treatment on rat striatal dopamine (DA) receptor activity

    SciTech Connect

    Roseboom, P.H.; Iwaniec, L.M.; Ackerman, J.M.; Gnegy, M.E.

    1986-03-05

    Upon administration of AMPH rats display a complex series of dose and time dependent behaviors and changes in dopaminergic activity. They found a decrease in D1 DA receptor-stimulated adenylate cyclase (DA-AC) activity in rat striatal membranes after acute in vivo AMPH at a dose and time of intense stereotyped behavior. The Ka for D1-AC activity increased and the Vmax decreased in striatal membranes from rats given 7.5 mg/kg AMPH i.p. and killed 1 hr later as compared to saline (SAL) controls. They examined whether the decrease of DA-AC was due to a change in receptor number or activation of GTP-binding protein, Ns. Female Holtzman rats were injected with SAL or 7.5 mg/kg AMPH and killed 1 hr later. A 27,000 x g striatal particulate fraction was prepared for AC assay or (/sup 3/H)DA binding with 10 nM spiroperidol. They found no difference in stimulation of AC by NaF, GTP or GppNHp at any dose tested in membranes from SAL- and AMPH-treated rats. Calmodulin-stimulated AC was also unchanged after AMPH. Specific binding at a saturating concentration of (/sup 3/H)DA was 191 +/- 31 and 117 +/- 14 fmol/mg prot in membranes from SAL- and AMPH-treated rats, respectively. This suggests an alteration is occurring at the level of the D1 receptor rather than at coupling of Ns with the AC catalytic subunit.

  7. PanDA Pilot Submission using Condor-G: Experience and Improvements

    NASA Astrophysics Data System (ADS)

    Zhao, Xin; Hover, John; Wlodek, Tomasz; Wenaus, Torre; Frey, Jaime; Tannenbaum, Todd; Livny, Miron; ATLAS Collaboration

    2011-12-01

    PanDA (Production and Distributed Analysis) is the workload management system of the ATLAS experiment, used to run managed production and user analysis jobs on the grid. As a late-binding, pilot-based system, the maintenance of a smooth and steady stream of pilot jobs to all grid sites is critical for PanDA operation. The ATLAS Computing Facility (ACF) at BNL, as the ATLAS Tier1 center in the US, operates the pilot submission systems for the US. This is done using the PanDA "AutoPilot" scheduler component which submits pilot jobs via Condor-G, a grid job scheduling system developed at the University of Wisconsin-Madison. In this paper, we discuss the operation and performance of the Condor-G pilot submission at BNL, with emphasis on the challenges and issues encountered in the real grid production environment. With the close collaboration of Condor and PanDA teams, the scalability and stability of the overall system has been greatly improved over the last year. We review improvements made to Condor-G resulting from this collaboration, including isolation of site-based issues by running a separate Gridmanager for each remote site, introduction of the 'Nonessential' job attribute to allow Condor to optimize its behavior for the specific character of pilot jobs, better understanding and handling of the Gridmonitor process, as well as better scheduling in the PanDA pilot scheduler component. We will also cover the monitoring of the health of the system.

  8. Whole-Genome Sequences of DA and F344 Rats with Different Susceptibilities to Arthritis, Autoimmunity, Inflammation and Cancer

    PubMed Central

    Guo, Xiaosen; Brenner, Max; Zhang, Xuemei; Laragione, Teresina; Tai, Shuaishuai; Li, Yanhong; Bu, Junjie; Yin, Ye; Shah, Anish A.; Kwan, Kevin; Li, Yingrui; Jun, Wang; Gulko, Pércio S.

    2013-01-01

    DA (D-blood group of Palm and Agouti, also known as Dark Agouti) and F344 (Fischer) are two inbred rat strains with differences in several phenotypes, including susceptibility to autoimmune disease models and inflammatory responses. While these strains have been extensively studied, little information is available about the DA and F344 genomes, as only the Brown Norway (BN) and spontaneously hypertensive rat strains have been sequenced to date. Here we report the sequencing of the DA and F344 genomes using next-generation Illumina paired-end read technology and the first de novo assembly of a rat genome. DA and F344 were sequenced with an average depth of 32-fold, covered 98.9% of the BN reference genome, and included 97.97% of known rat ESTs. New sequences could be assigned to 59 million positions with previously unknown data in the BN reference genome. Differences between DA, F344, and BN included 19 million positions in novel scaffolds, 4.09 million single nucleotide polymorphisms (SNPs) (including 1.37 million new SNPs), 458,224 short insertions and deletions, and 58,174 structural variants. Genetic differences between DA, F344, and BN, including high-impact SNPs and short insertions and deletions affecting >2500 genes, are likely to account for most of the phenotypic variation between these strains. The new DA and F344 genome sequencing data should facilitate gene discovery efforts in rat models of human disease. PMID:23695301

  9. Dioscorea Extract (DA-9801) Modulates Markers of Peripheral Neuropathy in Type 2 Diabetic db/db Mice

    PubMed Central

    Moon, Eunjung; Lee, Sung Ok; Kang, Tong Ho; Kim, Hye Ju; Choi, Sang Zin; Son, Mi-Won; Kim, Sun Yeou

    2014-01-01

    The purpose of this study was to investigate the therapeutic effects of DA-9801, an optimized extract of Dioscorea species, on diabetic peripheral neuropathy in a type 2 diabetic animal model. In this study, db/db mice were treated with DA-9801 (30 and 100 mg/kg, daily, p.o.) for 12 weeks. DA-9801 reduced the blood glucose levels and increased the withdrawal latencies in hot plate tests. Moreover, it prevented nerve damage based on increased nerve conduction velocity and ultrastructural changes. Decrease of nerve growth factor (NGF) may have a detrimental effect on diabetic neuropathy. We previously reported NGF regulatory properties of the Dioscorea genus. In this study, DA-9801 induced NGF production in rat primary astrocytes. In addition, it increased NGF levels in the sciatic nerve and the plasma of type 2 diabetic animals. DA-9801 also increased neurite outgrowth and mRNA expression of Tieg1/Klf10, an NGF target gene, in PC12 cells. These results demonstrated the attenuation of diabetic peripheral neuropathy by oral treatment with DA-9801 via NGF regulation. DA-9801 is currently being evaluated in a phase II clinical study. PMID:25414776

  10. Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity

    PubMed Central

    Otgaar, Tyrone C.; Bernert, Martin; Ferreira, Eloise; Reusch, Uwe; Knackmuss, Stefan; Little, Melvyn; Weiss, Stefan F. T.; Letsolo, Boitelo T.

    2015-01-01

    Cancer has become a major problem worldwide due to its increasing incidence and mortality rates. Both the 37kDa/67kDa laminin receptor (LRP/LR) and telomerase are overexpressed in cancer cells. LRP/LR enhances the invasiveness of cancer cells thereby promoting metastasis, supporting angiogenesis and hampering apoptosis. An essential component of telomerase, hTERT is overexpressed in 85–90% of most cancers. hTERT expression and increased telomerase activity are associated with tumor progression. As LRP/LR and hTERT both play a role in cancer progression, we investigated a possible correlation between LRP/LR and telomerase. LRP/LR and hTERT co-localized in the perinuclear compartment of tumorigenic breast cancer (MDA_MB231) cells and non-tumorigenic human embryonic kidney (HEK293) cells. FLAG® Co-immunoprecipitation assays confirmed an interaction between LRP/LR and hTERT. In addition, flow cytometry revealed that both cell lines displayed high cell surface and intracellular LRP/LR and hTERT levels. Knock-down of LRP/LR by RNAi technology significantly reduced telomerase activity. These results suggest for the first time a novel function of LRP/LR in contributing to telomerase activity. siRNAs targeting LRP/LR may act as a potential alternative therapeutic tool for cancer treatment by (i) blocking metastasis (ii) promoting angiogenesis (iii) inducing apoptosis and (iv) impeding telomerase activity. PMID:26545108

  11. Visual degradation in Leonardo da Vinci's iconic self-portrait: A nanoscale study

    NASA Astrophysics Data System (ADS)

    Conte, A. Mosca; Pulci, O.; Misiti, M. C.; Lojewska, J.; Teodonio, L.; Violante, C.; Missori, M.

    2014-06-01

    The discoloration of ancient paper, due to the development of oxidized groups acting as chromophores in its chief component, cellulose, is responsible for severe visual degradation in ancient artifacts. By adopting a non-destructive approach based on the combination of optical reflectance measurements and time-dependent density functional theory ab-initio calculations, we describe and quantify the chromophores affecting Leonardo da Vinci's iconic self-portrait. Their relative concentrations are very similar to those measured in modern and ancient samples aged in humid environments. This analysis quantifies the present level of optical degradation of the Leonardo da Vinci's self-portrait which, compared with future measurements, will assess its degradation rate. This is a fundamental information in order to plan appropriate conservation strategies.

  12. Crosslinking of hemin to a specific site on the 90-kDa ferritin repressor protein

    SciTech Connect

    Lin, Jihjing; Thach, R.E. ); Patino, M.M.; Gaffield, L.; Walden. W.E. ); Smith, A. )

    1991-07-15

    Incubation of a 90-kDa ferritin repressor protein (FRP) with small amounts of radiolabeled hemin resulted in the formation of a strong interaction between the two that was stable to SDS/PAGE. Of seven other proteins tested individually, only apohemopexin and bovine serum albumin showed similar crosslinking ability, albeit to a much lower extent. ({sup 14}C)Hemin specifically crosslinked to FRP in the presence of a 50-fold excess of total wheat germ proteins. Inclusion of catalase did not prevent the reaction of hemin with FRP, suggesting that H{sub 2}O{sub 2} is not involved. The subsequent addition of a stoichiometric amount of apohemopexin did not reverse the reaction. Exhaustive digestion of the complex with Staphylococcus aureus V8 protease produced a major labeled peptide of 17 kDa. These results show the existence of a highly specific, uniquely reactive hemin binding site on FRP.

  13. Iron abundance in the hot DA white dwarfs Feige 24 and G191 B2B

    NASA Technical Reports Server (NTRS)

    Vennes, Stephane; Chayer, Pierre; Thorstensen, John R.; Bowyer, Stuart; Shipman, Harry L.

    1992-01-01

    Attention is given to model calculations of the far- and extreme-UV line spectra of highly ionized Fe species (Fe IV, Fe V, and Fe VI) for hot high-gravity H-rich stars. A spectral analysis of 31 hr of exposure of the DA white dwarf Feige 24 with IUE in the echelle mode reveals the presence of Fe with an abundance relative to H by number of (5-10) x 10 exp -6 with an uncertainty dominated by the determination of stellar parameters. An analysis of IUE data from the white dwarf G191 B2B results in a similar Fe abundance if this star shares similar atmospheric parameters (Teff, g) with Feige 24. Fe is thus the second most abundant photospheric element in hot DA white dwarfs.

  14. Maximizing use of robot-arm no. 3 in da vinci-assisted thoracic surgery.

    PubMed

    Kajiwara, Naohiro; Maeda, Junichi; Yoshida, Koichi; Kato, Yasufumi; Hagiwara, Masaru; Kakihana, Masatoshi; Ohira, Tatsuo; Kawate, Norihiko; Ikeda, Norihiko

    2015-05-01

    We have previously reported on the importance of appropriate robot-arm settings and replacement of instrument ports in robot-assisted thoracic surgery, because the thoracic cavity requires a large space to access all lesions in various areas of the thoracic cavity from the apex to the diaphragm and mediastinum and the chest wall. (1 - 3) Moreover, it can be difficult to manipulate the da Vinci Surgical System using only arms No. 1 and No. 2 depending on the tumor location. However, arm No. 3 is usually positioned on the same side as arm No. 2, and sometimes it is only used as an assisting-arm to avoid conflict with other arms ( Fig. 1 ). In this report, we show how robot-arm No. 3 can be used with maximum effectiveness in da Vinci-assisted thoracic surgery. [Figure: see text]. PMID:26011219

  15. Development of noSQL data storage for the ATLAS PanDA Monitoring System

    NASA Astrophysics Data System (ADS)

    Potekhin, M.; ATLAS Collaboration

    2012-06-01

    For several years the PanDA Workload Management System has been the basis for distributed production and analysis for the ATLAS experiment at the LHC. Since the start of data taking PanDA usage has ramped up steadily, typically exceeding 500k completed jobs/day by June 2011. The associated monitoring data volume has been rising as well, to levels that present a new set of challenges in the areas of database scalability and monitoring system performance and efficiency. These challenges are being met with a R&D effort aimed at implementing a scalable and efficient monitoring data storage based on a noSQL solution (Cassandra). We present our motivations for using this technology, as well as data design and the techniques used for efficient indexing of the data. We also discuss the hardware requirements as they were determined by testing with actual data and realistic loads.

  16. A Case Study in Implementing DependencyBased Grammars Marie BOURDON, Lyne DA SYLVA, Michel GAGNON,

    E-print Network

    Gagnon, Michel

    A Case Study in Implementing Dependency­Based Grammars Marie BOURDON, Lyne DA SYLVA, Michel GAGNON,ldasylva,mgagnon,akharrat,sknoll,amaclachlan@machinasapiens.com http://www.machinasapiens.com Abstract In creating an English grammar check i ng sof t ware product , we implemented a large­coverage grammar based on the dependency grammar forma l i sm . Th i s i mp l

  17. Teorema da Diverg^encia e Teorema de Stokes (Resoluc~ao Sumaria)

    E-print Network

    Ventura, Joana

    Teorema da Diverg^encia e Teorema de Stokes (Resolu¸c~ao Sum´aria) 19 de Maio de 2009 1. Calcule o de S, conclu´imos que g induz a orienta¸c~ao correspondente `a normal exterior unit´aria, e que unit´aria indicada corresponde ent~ao `a normal unit´aria exterior n ao volume V limitado por D1 SD2

  18. Determinac~ao da parametrizac~ao e curvatura de uma superficie em R3

    E-print Network

    Natário, José

    , Karl Schwarzschild descobriu a solu¸c~ao das equa¸c~oes de Einstein correspondente ao campo de gravita´icie. Determina¸c~ao da m´etrica Se restringirmos o espa¸co-tempo de Schwarzschild a tr^es dimens~oes (t, r~ao, que (3) ´e a m´etrica medida pelos observadores esta- cion´arios no espa¸co-tempo de Schwarzschild

  19. The Handedness of Leonardo da Vinci: A Tale of the Complexities of Lateralisation

    ERIC Educational Resources Information Center

    McManus, I. C.; Drury, Helena

    2004-01-01

    The handedness of Leonardo da Vinci is controversial. Although there is little doubt that many of his well-attributed drawings were drawn with the left hand, the hatch marks of the shading going downwards from left to right, it is not clear that he was a natural left-hander, there being some suggestion that he may have become left-handed as the…

  20. Departamento de Matem' atica da Universidade de Coimbra ESTAT'iSTICA

    E-print Network

    Pascoal, Marta Margarida Braz

    Departamento de Matem' atica da Universidade de Coimbra ESTAT'iSTICA Ano lectivo: 1999/2000 Folha 3 18. O Jos'e tem de se deslocar urgentemente de Coimbra para a Esta¸c~ao de Santa Apol, a fim de poder chegar `a Esta¸c~ao de Coimbra B a tempo de apanhar o referido comboio. O Jos'e tem 20

  1. The experience of totally endoscopic coronary bypass grafting with the robotic system «Da Vinci» in Russia

    NASA Astrophysics Data System (ADS)

    Efendiev, V. U.; Alsov, S. A.; Ruzmatov, T. M.; Mikheenko, I. L.; Chernyavsky, A. M.; Malakhov, E. S.

    2015-11-01

    A new technology - a thoracoscopic coronary bypass grafting with the use of Da Vinci robotic system in Russia is represented by the experience of NRICP. The technology was introduced in Russia in 2011. Overall, one hundred endoscopic coronary artery bypass procedures were performed. We have compared and analyzed results of coronary artery stenting vs minimally invasive coronary artery bypass grafting. According to the results, totally endoscopic coronary artery bypass grafting has several advantages over alternative treatment strategies.

  2. Aconteceu no SEPT: Aula inaugural no Laboratrio de Ensaios Qumicos (LEQPetro) e visita ao Parque da Cincia

    E-print Network

    Paraná, Universidade Federal do

    com muito orgulho. Foto 1: Visão geral da aula pratica Foto 2: prof. Guimarães auxiliando os preocupado com a qualidade e excelência do ensino. Foto 3: Estudantes do 1º. ano na visita ao Parque Newton F

  3. Diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT: a clinical follow up study

    PubMed Central

    Menéndez-González, Manuel; Tavares, Francisco; Zeidan, Nahla; Salas-Pacheco, José M.; Arias-Carrión, Oscar

    2014-01-01

    The [123I]ioflupane—a dopamine transporter radioligand—SPECT (DaT-SPECT) has proven to be useful in the differential diagnosis of tremor. Here, we investigate the diagnoses behind patients with hard-to-classify tremor and normal DaT-SPECT. Therefore, 30 patients with tremor and normal DaT-SPECT were followed up for 2 years. In 18 cases we were able to make a diagnosis. The residual 12 patients underwent a second DaT-SPECT, were then followed for additional 12 months and thereafter the diagnosis was reconsidered again. The final diagnoses included cases of essential tremor, dystonic tremor, multisystem atrophy, vascular parkinsonism, progressive supranuclear palsy, corticobasal degeneration, fragile X–associated tremor ataxia syndrome, psychogenic parkinsonism, iatrogenic parkinsonism and Parkinson's disease. However, for 6 patients the diagnosis remained uncertain. Larger series are needed to better establish the relative frequency of the different conditions behind these cases. PMID:24744729

  4. Roles of a 67-kDa polypeptide in reversal of protein synthesis inhibition in heme-deficient reticulocyte lysate.

    PubMed Central

    Datta, B; Chakrabarti, D; Roy, A L; Gupta, N K

    1988-01-01

    During heme deficiency in reticulocyte lysates, the heme-regulated protein synthesis inhibitor, HRI, phosphorylates the alpha subunit of eukaryotic initiation factor 2 (eIF-2) and thus inhibits protein synthesis. Two factors, eIF-2 and a reticulocyte-lysate supernatant factor that we term RF, reverse this inhibition. We now report the following. (i) An active eIF-2 preparation contained, in addition to the three subunits (alpha, beta, and gamma), a 67-kDa polypeptide. Pretreatment of eIF-2 with polyclonal antibodies against either isolated alpha subunit or 67-kDa polypeptide almost completely inhibited the reversal activity. Upon further fractionation, three-subunit eIF-2 and the 67-kDa polypeptide were resolved. Neither the three-subunit eIF-2 nor the 67-kDa polypeptide alone was active in protein synthesis inhibition reversal. The activity was, however, restored by combining both the three-subunit eIF-2 and the 67-kDa polypeptide. (ii) Active RF preparations contained eIF-2 alpha (unphosphorylated) and beta subunits and the 67-kDa polypeptide. As with eIF-2, prior treatment of the RF preparation with antibodies to either the alpha subunit or the 67-kDa polypeptide almost completely inhibited the reversal activity. The RF preparation devoid of eIF-2 gamma subunit did not form ternary complex (Met-tRNA(fMet).eIF-2.GTP). The eIF-2 gamma subunit in the free form was isolated, and addition of this isolated gamma subunit to RF promoted significant ternary-complex formation. (iii) Purified HRI efficiently phosphorylated the alpha subunit in the three subunit eIF-2. However, the extent of such phosphorylation was significantly reduced when eIF-2 containing the 67-kDa polypeptide was used. The 67-kDa polypeptide apparently protected eIF-2 alpha subunit from HRI-catalyzed phosphorylation but did not inhibit HRI activity. Based on these results, we suggest that the protein synthesis inhibition reversal activity in both eIF-2 and RF is due to the same components--namely, eIF-2 alpha subunit and the 67-kDa polypeptide. The 67-kDa polypeptide protects eIF-2 alpha subunit from HRI-catalyzed phosphorylation and may also be a necessary component of the functioning eIF-2 molecule. Images PMID:3368443

  5. da Vinci robot-assisted keyhole neurosurgery: a cadaver study on feasibility and safety.

    PubMed

    Marcus, Hani J; Hughes-Hallett, Archie; Cundy, Thomas P; Yang, Guang-Zhong; Darzi, Ara; Nandi, Dipankar

    2015-04-01

    The goal of this cadaver study was to evaluate the feasibility and safety of da Vinci robot-assisted keyhole neurosurgery. Several keyhole craniotomies were fashioned including supraorbital subfrontal, retrosigmoid and supracerebellar infratentorial. In each case, a simple durotomy was performed, and the flap was retracted. The da Vinci surgical system was then used to perform arachnoid dissection towards the deep-seated intracranial cisterns. It was not possible to simultaneously pass the 12-mm endoscope and instruments through the keyhole craniotomy in any of the approaches performed, limiting visualization. The articulated instruments provided greater dexterity than existing tools, but the instrument arms could not be placed in parallel through the keyhole craniotomy and, therefore, could not be advanced to the deep cisterns without significant clashing. The da Vinci console offered considerable ergonomic advantages over the existing operating room arrangement, allowing the operating surgeon to remain non-sterile and seated comfortably throughout the procedure. However, the lack of haptic feedback was a notable limitation. In conclusion, while robotic platforms have the potential to greatly enhance the performance of transcranial approaches, there is strong justification for research into next-generation robots, better suited to keyhole neurosurgery. PMID:25516094

  6. Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement.

    PubMed

    Tolu, S; Eddine, R; Marti, F; David, V; Graupner, M; Pons, S; Baudonnat, M; Husson, M; Besson, M; Reperant, C; Zemdegs, J; Pagès, C; Hay, Y A H; Lambolez, B; Caboche, J; Gutkin, B; Gardier, A M; Changeux, J-P; Faure, P; Maskos, U

    2013-03-01

    Smoking is the most important preventable cause of mortality and morbidity worldwide. This nicotine addiction is mediated through the nicotinic acetylcholine receptor (nAChR), expressed on most neurons, and also many other organs in the body. Even within the ventral tegmental area (VTA), the key brain area responsible for the reinforcing properties of all drugs of abuse, nicotine acts on several different cell types and afferents. Identifying the precise action of nicotine on this microcircuit, in vivo, is important to understand reinforcement, and finally to develop efficient smoking cessation treatments. We used a novel lentiviral system to re-express exclusively high-affinity nAChRs on either dopaminergic (DAergic) or ?-aminobutyric acid-releasing (GABAergic) neurons, or both, in the VTA. Using in vivo electrophysiology, we show that, contrary to widely accepted models, the activation of GABA neurons in the VTA plays a crucial role in the control of nicotine-elicited DAergic activity. Our results demonstrate that both positive and negative motivational values are transmitted through the dopamine (DA) neuron, but that the concerted activity of DA and GABA systems is necessary for the reinforcing actions of nicotine through burst firing of DA neurons. This work identifies the GABAergic interneuron as a potential target for smoking cessation drug development. PMID:22751493

  7. Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein.

    PubMed Central

    Guan, J L; Trevithick, J E; Hynes, R O

    1991-01-01

    We describe a 120-kDa protein (pp120) that is phosphorylated on tyrosine in cells attached to fibronectin-coated surfaces. The protein appears to be located in focal contacts where it codistributes with beta 1 integrins. pp120 is distinct from the beta 1 subunit of integrins and from vinculin and alpha-actinin. pp120 is rapidly dephosphorylated in cells suspended by trypsinization but becomes rapidly phosphorylated in cells attaching and spreading on fibronectin. Attachment of cells to RGD-containing peptides, polylysine, or concanavalin A is not sufficient to induce phosphorylation of pp120. The 120-kDa cell-binding domain of fibronectin can induce some phosphorylation of pp120, but further phosphorylation occurs in the presence also of the heparin-binding domain of fibronectin. Phosphorylation of pp120 precedes, but is correlated with, subsequent cell spreading. Phosphorylation of pp120 can also be triggered by attachment of cells to anti-integrin antibodies, and this requires the cytoplasmic domain of the integrin beta 1 subunit. Thus interaction of beta 1 integrins with extracellular ligands (fibronectin or antibodies) triggers phosphorylation of an intracellular 120-kDa protein, pp120, that may be involved in the responses of cells to attachment. Images PMID:1725602

  8. [History of robotics: from archytas of tarentum until Da Vinci robot. (Part II)].

    PubMed

    Sánchez-Martín, F M; Jiménez Schlegl, P; Millán Rodríguez, F; Salvador-Bayarri, J; Monllau Font, V; Palou Redorta, J; Villavicencio Mavrich, H

    2007-03-01

    Robotic surgery is a reality. In order to to understand how new robots work is interesting to know the history of ancient (see part i) and modern robotics. The desire to design automatic machines imitating humans continued for more than 4000 years. Archytas of Tarentum (at around 400 a.C.), Heron of Alexandria, Hsieh-Fec, Al-Jazari, Bacon, Turriano, Leonardo da Vinci, Vaucanson o von Kempelen were robot inventors. At 1942 Asimov published the three robotics laws. Mechanics, electronics and informatics advances at XXth century developed robots to be able to do very complex self governing works. At 1985 the robot PUMA 560 was employed to introduce a needle inside the brain. Later on, they were designed surgical robots like World First, Robodoc, Gaspar o Acrobot, Zeus, AESOP, Probot o PAKI-RCP. At 2000 the FDA approved the da Vinci Surgical System (Intuitive Surgical Inc, Sunnyvale, CA, USA), a very sophisticated robot to assist surgeons. Currently urological procedures like prostatectomy, cystectomy and nephrectomy are performed with the da Vinci, so urology has become a very suitable speciality to robotic surgery. PMID:17658147

  9. Attachment of group B streptococci to macrophages is mediated by a 21-kDa protein.

    PubMed

    Smith, L M; Laganas, V; Pistole, T G

    1998-02-01

    Group B Streptococcus (GBS) is able to bind to human macrophages in vitro in the absence of exogenous opsonins. The exact mechanisms that mediate this attachment are unclear. This study was undertaken to determine what protein adhesins are present on the surface of GBS that mediate attachment to macrophages. We have identified a 21-kDa protein from the envelope of GBS type III that directly binds to macrophages as determined by Western blot analysis. Antiserum against this protein was able to inhibit binding of GBS to macrophages by greater than 80% as measured by flow cytometry. Antiserum against the 21-kDa protein cross-reacted with 21-kDa proteins from GBS type Ib, type II, type III (COH31 and MR732) and type IV, as well as Staphyloccus epidermidis, but not GBS type Ia, Listeria monocytogenes or Enterococcus faecalis. This protein may be important in mediating the attachment of GBS to macrophages in an opsonin-poor environment. PMID:9544775

  10. Migration and urban schistosomiasis. The case of São Lourenço da Mata, northeast of Brazil.

    PubMed

    Ximenes, R A; Southgate, B; Smith, P G; Guimarães Neto, L

    2000-01-01

    A population-based case-control design was used to investigate the association between migration, urbanisation and schistosomiasis in the Metropolitan Region of Recife, Northeast of Brazil. 1022 cases and 994 controls, aged 10 to 25, were selected. The natives and the migrants who come from endemic areas have a similar risk of infection. On the other hand, the risk of infection of migrants from nonendemic areas seems to be related with the time elapsed since their arrival in São Lourenço da Mata; those who have been living in that urban area for 5 or more years have a risk of infection similar to that of the natives. Those arriving in the metropolitan region of Recife mostly emigrate from "zona da mata" and "zona do agreste" in the state of Pernambuco. Due to the changes in the sugar agroindustry and to the increase in the area used for cattle grazing these workers were driven to villages and cities. The pattern of urbanisation created the conditions for the establishment of foci of transmission in São Lourenço da Mata. PMID:10968884

  11. Regolith grain size and cohesive strength of near-Earth Asteroid (29075) 1950 DA

    NASA Astrophysics Data System (ADS)

    Gundlach, B.; Blum, J.

    2015-09-01

    Due to its fast rotation period of 2.12 h, about half of the surface of near-Earth Asteroid (29075) 1950 DA experiences negative (i.e., outward directed) acceleration levels (Rozitis, B., Maclennan, E., Emery, J.P. [2014]. Nature 512, 174-176). Thus, cohesion of the surface material is mandatory to prevent rotational breakup of the asteroid. Rozitis et al. (Rozitis, B., Maclennan, E., Emery, J.P. [2014]. Nature 512, 174-176) concluded that a grain size of ?6 cm or lower is needed to explain the required cohesive strength of 64-20+12Pa . Here, we present another approach to determine the grain size of near-Earth Asteroid (29075) 1950 DA by using the thermal inertia value from Rozitis et al. (Rozitis, B., Maclennan, E., Emery, J.P. [2014]. Nature 512, 174-176) and a model of the heat conductivity of the surface regolith (Gundlach, B., Blum, J. [2013]. Icarus 223, 479-492). This method yields a mean particle radius ranging from 32 ?m to 117 ?m. The derived grain sizes are then used to infer the cohesive strength of the surface material of Asteroid (29075) 1950 DA (ranging from 24 Pa to 88 Pa), by using laboratory measurements of the tensile strength of powders.

  12. Fenomenologia da Supercondutividade e Supercondutores Mesosc\\'opicos Phenomenology of the superconductivity and mesoscopic superconductors

    E-print Network

    Zadorosny, Rafael; Duarte, Elwis C S; Sardella, Edson

    2015-01-01

    Em geral, quando a teoria fenomenol\\'ogica de Ginzburg-Landau para supercondutores \\'e trabalhada, pouco se esclarece aos alunos sobre a origem da mesma. Esta tem como base conceitos termodin\\^amicos como fen\\^omenos cr\\'iticos e transi\\c{c}\\~oes de fase que, se devidamente tratados, enriquecem de sobremaneira a aula sobre tal assunto. Assim, neste trabalho apresentamos uma sequ\\^encia para o desenvolvimento da principal teoria fenomenol\\'ogica da supercondutividade. Iniciamos com uma breve introdu\\c{c}\\~ao aos fen\\^omenos cr\\'iticos e transi\\c{c}\\~oes de fase e, ent\\~ao, desenvolvemos a teoria de Landau para transi\\c{c}\\~oes de fase de segunda ordem. Ap\\'os isso, expomos a teoria de Ginzburg-Landau, e a teoria de Ginzburg-Landau dependente do tempo. Aplicamos esta \\'ultima para o caso de dois sistemas supercondutores mesosc\\'opicos, um homog\\^eneo e outro com defeitos superficiais. Observa-se que os defeitos interferem de sobremaneira na din\\^amica de v\\'ortices do sistema. Palavras chave: Ginzburg-Landau, m...

  13. Production of large transverse momentum dileptons and photons in $pp$, $dA$ and $AA$ collisions by photoproduction processes

    E-print Network

    Fu, Yong-Ping

    2011-01-01

    The production of large $P_{T}$ dileptons and photons originating from photoproduction processes in $pp$, $dA$ and $AA$ collisions is calculated. We find that the contribution of dileptons and photons produced by photoproduction processes is not prominent at RHIC energies. However, the numerical results indicate that the modification of photoproduction processes becomes evident in the large $P_{T}$ region for $pp$, $dA$ and $AA$ collisions at LHC energies.

  14. Identification and purification of a novel 120-kDa protein that recognizes the cAMP-responsive element

    SciTech Connect

    Andrisani, O.; Dixon, J.E. )

    1990-02-25

    The TGACGTCA (CRE) motif required for function by a number of cellular (somatostatin, enkephalin, alpha-human chorionic gonadotropin) and viral (Ad5 E1A-inducible, HTLV-1 TAX-inducible) genes is the site of interaction of multiple sequence-specific complexes. A protocol has been developed for the fractionation and purification of these activities. We report here the purification from HeLa nuclear extracts of a novel 120-kDa polypeptide which by Southwestern blots, gel retardation, and UV cross-linking assays displays CRE-specific binding. The CRE-affinity purified 120-kDa protein displays properties distinct from those of the 43-kDa CREB/ATF polypeptide. The 120-kDa protein is readily phosphorylated in vitro by protein kinase C but not by protein kinase A, suggesting that this molecule may mediate cellular signals distinct from the cAMP-responsive pathway. In vitro transcription-complementation assays utilizing the purified 120-kDa protein failed to transactivate the cAMP-responsive somatostatin promoter suggesting that the mode of action of this 120-kDa polypeptide may require an activation step distinct from the cAMP-signaling pathway.

  15. Projeto educação em ciências com observatórios virtuais: a participação da Escola Moppe no período 2000-2003

    NASA Astrophysics Data System (ADS)

    Wuensche, C. A.; Gavioli, E.; Oliveira, A. L. P. R. S.; da Silva, C.; Cardoso, H. P.; Estácio, S.

    2003-08-01

    O projeto Educação em Ciências com Observatórios Virtuais foi concebido pelo Instituto Astronômico e Geofísico da USP, agregando diversas instituições de ensino e pesquisa no país para desenvolver competências diversas na educação fundamental, média e superior utilizando a astronomia como ferramenta multidisciplinar. Este trabalho descreve a participação da MOPPE, escola-piloto do INPE no projeto, no período de 2000-2003. Serão apresentadas 1) a criação de um clube de ciências (1999 a 2001) cujo tema foi a colonização de Marte e 2) a ementa de astronomia trabalhada com as 7a. e 8a. séries do ensino fundamental. A proposta do projeto Colonizando Marte foi estudar diversos aspectos de uma missão interplanetária e construir experiementos que permitissem quantificar esses aspectos. Os resultados obtidos incluiram apresentações nas SBPC Jovem em 2000 e 2001. Discutiremos também as ementas de astronomia trabalhadas desde 2001 e o envolvimento dos alunos com atividades ligadas a astronomia, fora da aula de ciências. A inclusão de astronomia no currículo das últimas séries motivou a participação de mais alunos culminando com a conquista de duas medalhas para alunos da 7a. série na Olimpiada Brasileira de Astronomia em 2002. Houve também um aumento no número de participantes na OBA 2003 e nos projetos de astronomia mais elaborados nas Feira de Ciências de 2001 e 2002. Destacamos em 2003 a inclusão da MOPPE no projeto TIE - Telescopes in Education - da NASA, que utiliza o telescópio do Observatório de Mount Wilson (EUA) para observações remotas em projetos pedagógicos para o ensino de astronomia.

  16. Effect of DA-8159, a Selective Phosphodiesterase Type 5 Inhibitor, on Electroretinogram and Retinal Histology in Rabbits

    PubMed Central

    Kang, Kyung Koo; Ahn, Gook Jun; Shim, Hyun Joo; Kim, Won Bae

    2004-01-01

    DA-8159, a selective inhibitor of phosphodiesterase type 5, was developed as a new drug for erectile dysfunction. The effect of DA-8159 on the electroretinogram (ERG) and the retinal histopathology were evaluated in rabbits. The ERG was performed prior to, and 1 and 5 hr after DA-8159 (5 to 30 mg/kg) administration. The plasma concentration of DA-8159 was determined at each time point, and retinal microscopic examination was also performed. There was no statistically significant ERG change at any dose or at any time. Though the 30 Hz flicker showed a prolongation of the implicit time at 5 hr after the administration of either DA-8159 15 mg or 30 mg/kg (p<0.05), but concurrent amplitude decreases were not statistically significant. At a dose of 5 mg/kg, no test drug was detected in the blood after either 1 or 5 hr. At either 15 mg/kg or 30 mg/kg, there was a dose-dependent increase in the blood concentration after 1 hr of drug administration, which decreased with time. In light and electron microscopic examinations of the retina, there was no remarkable change at any dose. These results suggest DA-8159 has a low risk potential to the retina, but further evaluation on the visual functions in human is needed. PMID:15308852

  17. The Greek Database of Seismogenic Sources (GreDaSS): the new version.

    NASA Astrophysics Data System (ADS)

    Caputo, Riccardo; Pavlides, Spyros; GreDaSS Working Group

    2014-05-01

    The Greek Database of Seismogenic Sources (GreDaSS) is a repository of geological, tectonic and active fault data for the Greek territory and its surroundings including sectors of western Anatolia, southern Bulgaria, FYR of Macedonia and Albania. The principal aim of this international project is to create a homogenized framework of all data relevant to the seismotectonics, and especially the seismic hazard assessment, of Greece and its surroundings as well as a common research platform for performing seismic hazard analyses, modelling and scenarios from specific seismogenic structures. GreDaSS represents an on-going project based on the results of decades of investigations by the GreDaSS Working Group* and by numerous other researchers working on the active tectonics of the broader Aegean Region. Members of the WG have contributed in several national and European projects like FAUST (Faults as a seismological tool, 1998-2000) and SHARE (Seismic Hazard and Armonization in Europe, 2009-2012). The database is continuously updated by the WG, with the aim of improving its completeness in terms of seismogenic sources analysed and included, but also of enriching and better defining all parametric and ancillary information on each source. Preliminary and partial versions of GreDaSS have been already presented at previous congresses (Pavlides et al., 2010; Caputo et al., 2012; Sboras et al., 2013), but at next EGU the whole area and the most recent version of the database will be displayed. *) the principal scientific contributors belonging to the GreDaSS WG are: Sboras. S., Chatzipetros A., Koukouvelas I., Michailidou A., Valkaniotis S., Tarabusi G. Caputo R., Chatzipetros A., Pavlides S. and Sboras S. (2012): Ann. Geophysics, 55(5), 859-894, doi: 10.4401/ag-5168 Pavlides S., Caputo R., Sboras S., Chatzipetros A., Papathanasiou G. & Valkaniotis S. (2010): Bull. Geol. Soc. Greece, 43(1), 486-494 Sboras S., Pavlides S., Caputo R., Chatzipetros A., Michailidou A., Valkaniotis S. and Papathanasiou G. (2013): Boll. Geofis. Teor. Appl., 13 pp. doi: 10.4430/bgta0101.

  18. The Near-Earth Flyby of Asteroid 2012 DA14 (Invited)

    NASA Astrophysics Data System (ADS)

    Moskovitz, N. A.; Endicott, T.; Lister, T.; Ryan, B.; Ryan, E. V.; Willman, M.; Hergenrother, C.; Binzel, R. P.; Polishook, D.; DeMeo, F.; Bennechi, S.; Sheppard, S.; Marchis, F.; Angusteijn, T.; Birthwhistle, P.; Verveer, A.; Gulbis, A.; Nagayama, T.; Gilmore, A.; Kilmartin, P.

    2013-12-01

    On UT 2013 February 15, the elongated 20x40 meter near-Earth asteroid 2012 DA14 made a close flyby of the Earth at a distance of approximately 27,000 km or 4 Earth-radii. This passage was inside the orbital distance of geosynchronous satellites and close to the Earth's Roche limit. This close encounter was unprecedented in our advance knowledge of the incoming trajectory, thereby allowing us to forge a detailed coordinated plan for observation and testing of physical models predicting tidal effects near our planet's Roche limit. Predicted outcomes of such close encounters include tidal disruption, changes in rotation state, and mass loss or mass redistribution due to seismic shaking. Each of these effects sensitively depend on how tidal energy is dissipated in the interior of the asteroid: a rubble pile will dissipate tidal energy differently than a solid or partially fractured monolith. The internal properties of asteroids in general and particularly those in the size range of 2012 DA14 are largely unknown. This encounter represents one of the first ever opportunities to observationally test models of the interior structure of small planetary bodies. We will present the results of a large multi-observatory campaign focused on 2012 DA14. This campaign includes data from shortly after discovery in 2012 and surrounding the close approach of the asteroid in February of 2013. These data were collected with over a dozen telescopes worldwide, ranging in aperture from 1m to 8m and include major facilities in Chile, Australia, New Zealand, South Africa, Israel, Hawaii, Arizona, New Mexico, and the Canary Islands. We will highlight the outcome of pre- and post-flyby visible-wavelength photometric and spectroscopic observations. This will include clear evidence that 2012 DA14 is now in a non-principal axis rotation state, requiring a multi-periodic tumbling model to fit its post-flyby rotational light curve. Such a complex rotation state is consistent with models for the effects of gravitational interactions during close planetary encounters. The ultimate goal of this campaign will be to investigate changes to 2012 DA14's physical properties induced by its gravitational interactions with the Earth.

  19. Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice.

    PubMed

    Albers, Shawn; Inthathirath, Fatima; Gill, Sandeep K; Winick-Ng, Warren; Jaworski, Ewa; Wong, Daisy Y L; Gros, Robert; Rylett, R Jane

    2014-09-01

    Alzheimer disease (AD) is associated with increased amyloidogenic processing of amyloid precursor protein (APP) to ?-amyloid peptides (A?), cholinergic neuron loss with decreased choline acetyltransferase (ChAT) activity, and cognitive dysfunction. Both 69-kDa ChAT and 82-kDa ChAT are expressed in cholinergic neurons in human brain and spinal cord with 82-kDa ChAT localized predominantly to neuronal nuclei, suggesting potential alternative functional roles for the enzyme. By gene microarray analysis, we found that 82-kDa ChAT-expressing IMR32 neural cells have altered expression of genes involved in diverse cellular functions. Importantly, genes for several proteins that regulate APP processing along amyloidogenic and non-amyloidogenic pathways are differentially expressed in 82-kDa ChAT-containing cells. The predicted net effect based on observed changes in expression patterns of these genes would be decreased amyloidogenic APP processing with decreased A? production. This functional outcome was verified experimentally as a significant decrease in BACE1 protein levels and activity and a concomitant reduction in the release of endogenous A?1-42 from neurons cultured from brains of AD-model APP/PS1 transgenic mice. The expression of 82-kDa ChAT in neurons increased levels of GGA3, which is involved in trafficking BACE1 to lysosomes for degradation. shRNA-induced decreases in GGA3 protein levels attenuated the 82-kDa ChAT-mediated decreases in BACE1 protein and activity and A?1-42 release. Evidence that 82-kDa ChAT can enhance GGA3 gene expression is shown by enhanced GGA3 gene promoter activity in SN56 neural cells expressing this ChAT protein. These studies indicate a novel relationship between cholinergic neurons and APP processing, with 82-kDa ChAT acting as a negative regulator of A? production. This decreased formation of A? could result in protection for cholinergic neurons, as well as protection of other cells in the vicinity that are sensitive to increased levels of A?. Decreasing levels of 82-kDa ChAT due to increasing age or neurodegeneration could alter the balance towards increasing A? production, with this potentiating the decline in function of cholinergic neurons. PMID:24844149

  20. Analyzing the relation between the microbial diversity of DaQu and the turbidity spoilage of traditional Chinese vinegar.

    PubMed

    Li, Pan; Li, Sha; Cheng, Lili; Luo, Lixin

    2014-07-01

    Vinegar is a traditional fermented condiment, and the microbial diversity of DaQu makes the quality of vinegar products. Recently, turbidity spoilage of vinegar sharply tampered with the quality of vinegar. In this study, the relation between the microbial diversity of DaQu and turbidity spoilage of vinegar was analyzed by plating technique, PCR-denaturing gradient gel electrophoresis (DGGE), and high-performance liquid chromatography (HPLC). The 16S rRNA sequencing and DGGE analysis indicated that Bacillus (Bacillus subtilis, Bacillus amyloliquefaciens, and Bacillus thuringiensis) and Lactobacillus (including Lactobacillus acidipiscis and Lactobacillus pobuzihii) species were the dominant contaminants in vinegar products. Meanwhile, DGGE analysis showed that the dominant bacteria in DaQu belonged to genera Bacillus, Lactobacillus, Pseudomonas, Weissella, Saccharopolyspora, Enterobacter, and Pantoea. However, only two yeast species (Pichia kudriavzevii and Saccharomycopsis fibuligera) and seven mold species including Aspergillus oryzae, Aspergillus niger, Aspergillus candidus, Rhizopus microspores, Eurotium herbariorum, Absidia corymbifera, and Eupenicillium javanicum were detected in the DaQu. The population level of fungi was below 5 log CFU/g in DaQu. The chemical and physical properties of vinegar and sediments were also determined. On the basis of a combined microbial diversity-chemical analysis, we demonstrated that turbidity spoilage of vinegar was a result of cooperation among the low population level and abundance of fungal species in DaQu, the suitable climate conditions, and the contaminants in vinegar. This is the first report to analyze the relation between the microbial diversity of DaQu and turbidity spoilage of vinegar. PMID:24691870

  1. Expression, subcellular location and modification of the 50 kDa protein encoded by ORF2 of the apple chlorotic leaf spot trichovirus genome.

    PubMed

    Sato, K; Yoshikawa, N; Takahashi, T; Taira, H

    1995-06-01

    A putative movement protein of molecular mass 50 kDa encoded by the ORF2 of the apple chlorotic leaf spot virus (ACLSV) genome was expressed in Escherichia coli using an expression vector and was then used to produce an antiserum. Immunoblot analysis using an antiserum raised against this protein showed that the ORF2 protein of ACLSV was detected in both cell wall and cell membrane fractions prepared from infected Chenopodium quinoa tissues. The ORF2 protein from infected tissues had a molecular mass of 52 kDa, larger than that of the full-length ORF2 protein (50 kDa protein) expressed in E. coli. Incubation of the 52 kDa protein with alkaline phosphatase resulted in a decrease in its apparent molecular mass from 52 kDa to 50 kDa, strongly suggesting that the ORF2 protein of ACLSV is phosphorylated in infected plant tissues. PMID:7782779

  2. Projeto do sistema anti-ressonante da fiação dos transdutores para o detector Mario Schenberg

    NASA Astrophysics Data System (ADS)

    Vieira, S. J.., Jr.; Melo, J. L.

    2003-08-01

    O detector de ondas gravitacionais Mario Schenberg está sendo projetado e construído pelo grupo Gráviton. Sua construção está ocorrendo no Laboratório de Estado Sólido e Baixas Temperaturas (LESBT) da Universidade de São Paulo, na cidade de São Paulo. Esse detector possui uma massa ressonante esférica de cobre-alumínio, com 65 cm de diâmetro, pesando aproximadamente 1150 Kg, suspensa por um sistema de isolamento vibracional, que se encontra em fase de testes preliminares. A real eficácia desse sistema, entretanto, só poderá ser comprovada quando o detector estiver aparelhado com, pelo menos, um transdutor eletromecânico de altíssima sensibilidade acoplado à massa ressonante. Neste momento, não só este sistema de isolamento vibracional será posto em teste, como o do projeto da fiação que transporta os sinais de microondas até os transdutores e destes para a pré-amplificação. Apesar dessa fiação ter sido projetada para não apresentar nenhum contato com a superfície esférica da antena, de maneira a não haver nenhuma transmissão de ruído vibracional do laboratório para esta, deve-se minimizar o ruído microfônico produzido nessa fiação por oscilações mecânicas, uma vez que ela não utiliza nenhum sistema de isolamento vibracional. Com o intuito de resolver este problema, projetamos uma estrutura, formada por pequenos cilindros conectados por barras, a qual não terá nenhuma ressonância mecânica na faixa de freqüências de interesse para detecção (3000 - 3400 Hz). Desta forma, as vibrações nessa faixa não serão amplificadas. O projeto foi feito usando iterativamente, de maneira a otimizar os resultados obtidos, o programa de elementos finitos Msc/Nastran. Através de simulações feitas neste programa, determinamos os parâmetros geométricos ideais a serem utilizados, os quais proporcionam a maior região espectral de interesse livre de ressonâncias.

  3. Abnormality of epiphyseal plate induced by selenium deficiency diet in two generation DA rats.

    PubMed

    Min, Zixin; Zhao, Wenxiang; Zhong, Nannan; Guo, Yuanxu; Sun, Mengyao; Wang, Quancheng; Zhang, Rui; Yan, Jidong; Tian, Lifang; Zhang, Fujun; Han, Yan; Ning, Qilan; Meng, Liesu; Sun, Jian; Lu, Shemin

    2015-08-01

    This study aimed to observe the effects of Se deficiency on epiphyseal plates of two generation DA rats fed with artificial total synthetic low Se diet. All F0 and F1 DA rats were fed with synthetic low Se diet (SeD group) and low Se diet supplied with Se (SeS group). The levels of selenium and enzyme activities of GPx were detected in plasma of the rats. General growth of bone and articular cartilage was measured macroscopically and microscopically. The epiphyseal plate of femur heads or tibia were obtained to histological and immunohistochemical examinations. The cartilage from left knee joints and femur heads was used to detect the gene expression of collagens, ADAMTSs and several selenoproteins by RT-qPCR. Two generation SeD rats showed Se insufficiency status. The thicknesses of the femur and tibial epiphyseal plates in both F0 and F1 SeD rats were significantly less than that of SeS rats. In F1 generation, SeD rats showed much fewer proliferative chondrocyte layers than SeS ones. Importantly, two generation SeD rats both showed significantly more serious pathological changes of epiphyseal plates. In two generation rats, gene expressions of COL II, GPx1 and GPx4 were significantly down-regulated in SeD rats than SeS ones; meanwhile ADAMTS-4 showed an up-regulated expression in cartilage. Dietary Se deficiency can apparently cause epiphyseal plate lesion and decrease cartilage type II collagen production and GPx1 activity in two generation DA rats fed with the artificial total synthesis low Se diet. PMID:26011228

  4. [The Vitruvian Man: an anatomical drawing for proportions by Leonardo Da Vinci].

    PubMed

    Le Floch-Prigent, P

    2008-12-01

    The aim of the study was to find out and to analyse the text by Vitruvius which inspired the famous drawing by Leonardo da Vinci (circa 1490) kept in the Galleria dell'Accademia, in Venezia, Italy: the man inscribed in one circle and in one square. The book "de Architectura" by Vitruvius Marcus Pollio was printed several times since the Renaissance when both the roman architecture of antiquity and this text became very popular. From a French translation by Claude Perrault in 1864, it became easy to find a French translation with the original text in Latin (Paris, 2003, Les Belles Lettres, French text by Pierre Gros). The drawing by Leonardo da Vinci illustrates with great accuracy and fidelity the quotation of Vitruvius (with the exception of two of the 12 main relationships). The genius of Leonardo da Vinci was to keep only one trunk, head and neck for two pairs of limbs: scapular and pelvic; to make the circle tangent to the lower edge of the square; to adjust a few features of the quotation for the equilibrium of the whole figure; and of course to bring his incredible skill as a drawer (one of the best of his century). The drawing was made on a sheet of paper 344x245mm, in black ink which became dark brown with time; several lines complete the figure above and below; a short caption and a horizontal scale appear just under the drawing. The celebrity of the drawing, a symbol of the Renaissance, of the equilibrium of man and mankind, of the universality of the artists and intellectuals of the time (Humanism) made it iconic and it has been constantly reproduced and adapted especially for advertisement and logos, not only in the medical field. PMID:18951824

  5. Identification and characterization of a novel 34 kDa merozoite protein in Babesia orientalis.

    PubMed

    He, Lan; Fan, Lizhe; Liu, Qin; Hu, Jinfang; Miao, Xiaoyan; Huang, Yuan; He, Pei; He, Junwei; Yu, Long; Khan, Muhammad Kasib; Zhou, Yanqin; Shen, Bang; Zhao, Junlong

    2015-09-15

    A novel Babesia orientalis 34 kDa protein (designated BoP34) was obtained by immunoscreening of a cDNA expression library using B. orientalis infected water buffalo serum. The complete nucleotide sequence of the BoP34 was 1088 bp, which contained one open reading frame (ORF), two untranslated regions (UTRs) and a poly (A) tail. The length of ORF was 933 bp, encoding a polypeptide of 310 aa with a predicted size of 34 kDa. BLAST analysis showed that the nucleotide sequence of BoP34 had 71% similarity with that of the Babesia bovis gene XM_001611335, which encodes a nuclear movement family protein. This suggested that BoP34 is a homologous of the movement family protein. Structural analysis of the BoP34 protein indicated a CS domain which may interact with the ATPase domain of the heat shock protein 90. A truncated version of BoP34 was cloned into the expression vector pET-32a and subsequently expressed and purified from the Escherichia coli Rosetta™ (DE3) pLysS stain as a Trx-fusion (designated rBoP34-T). Antibodies in the serum of a B. orientalis-infected water buffalo were able to recognize this protein in immune-bloting analysis. Rabbit antibodies raised against rBoP34-T could detecte native BoP34 (34 kDa) in B. orientalis-infected water buffalo erythrocytes. These results suggested that BoP34 might be a good diagnostic antigen for the specific detection of anti-B. orientalis antibody in water buffalo. Further research is required to explore the biological function and diagnostic potential of this molecule. PMID:26169218

  6. OCT structural examination of Madonna dei Fusi by Leonardo da Vinci

    NASA Astrophysics Data System (ADS)

    Targowski, Piotr; Iwanicka, Magdalena; Sylwestrzak, Marcin; Kaszewska, Ewa A.; Frosinini, Cecilia

    2013-05-01

    Madonna dei Fusi (`Madonna of the Yarnwider') is a spectacular example of Italian Renaissance painting, attributed to Leonardo da Vinci. The aim of this study is to give an account of past restoration procedures. The evidence of a former retouching campaign will be presented with cross-sectional images obtained non-invasively with Optical Coherence Tomography (OCT). Specifically, the locations of overpaintings/retouchings with respect to the original paint layer and secondary varnishes will be given. Additionally, the evidence of a former transfer of the pictorial layer to the new canvas support by detecting the presence of its structure incised into paint layer will be shown.

  7. Epidemiological evidence in law: a comment on Supreme Court Decision 2011Da22092, South Korea.

    PubMed

    Broadbent, Alex

    2015-01-01

    This paper offers a commentary on three aspects of the Supreme Court's recent decision (2011Da22092). First, contrary to the Court's finding, this paper argues that epidemiological evidence can be used to estimate the probability that a given risk factor caused a disease in an individual plaintiff. Second, the distinction between specific and non-specific diseases, upon which the Court relies, is shown to be without scientific basis. Third, this commentary points out that the Court's finding concerning defect of expression effectively enables tobacco companies to profit from the efforts of epidemiologists and others involved in public health to raise awareness of the dangers of smoking. PMID:26063352

  8. [The anatomy of a reduced skull model--visualisation of Leonardo da Vinci's anthropology].

    PubMed

    Ahner, E

    2008-04-01

    The article focuses on a rare example of a miniature skull of unknown origin. The profoundness of the anatomical details, conjoint with outstanding virtuosity, reminds of Leonardo da Vinci's anatomical skull studies and asks for additional interpretation beside the emblematic "memento mori"-character. Following the miscellaneous topics of his skull studies an anatomical-anthropological interpretation is proposed. For such a project the mergence of anthropology, history of medicine and history of art was mandatory. Concerning some discrepancies within the anatomical realism, the depiction of a pathology is discussed and beyond the visualisation of a historic concept of brain function. PMID:18548818

  9. MA092 Geometria plana e analitica Comprimento da circunfer^encia -Area do circulo

    E-print Network

    Gomes, Francisco A. M.

    MA092 ­ Geometria plana e anal´itica Comprimento da circunfer^encia - ´Area do c´irculo Francisco A) 51.758 voltas Francisco A. M. Gomes (UNICAMP - IMECC)MA092 ­ Geometria plana e anal´itica Setembro de´itica Setembro de 2014 5 / 14 ´Area do c´irculo C´irculo ´Area A ´area de um c´irculo de raio R ´e dada por AC

  10. HyDA-Vista: towards optimal guided selection of k-mer size for sequence assembly

    PubMed Central

    2014-01-01

    Motivation Intimately tied to assembly quality is the complexity of the de Bruijn graph built by the assembler. Thus, there have been many paradigms developed to decrease the complexity of the de Bruijn graph. One obvious combinatorial paradigm for this is to allow the value of k to vary; having a larger value of k where the graph is more complex and a smaller value of k where the graph would likely contain fewer spurious edges and vertices. One open problem that affects the practicality of this method is how to predict the value of k prior to building the de Bruijn graph. We show that optimal values of k can be predicted prior to assembly by using the information contained in a phylogenetically-close genome and therefore, help make the use of multiple values of k practical for genome assembly. Results We present HyDA-Vista, which is a genome assembler that uses homology information to choose a value of k for each read prior to the de Bruijn graph construction. The chosen k is optimal if there are no sequencing errors and the coverage is sufficient. Fundamental to our method is the construction of the maximal sequence landscape, which is a data structure that stores for each position in the input string, the largest repeated substring containing that position. In particular, we show the maximal sequence landscape can be constructed in O(n + n log n)-time and O(n)-space. HyDA-Vista first constructs the maximal sequence landscape for a homologous genome. The reads are then aligned to this reference genome, and values of k are assigned to each read using the maximal sequence landscape and the alignments. Eventually, all the reads are assembled by an iterative de Bruijn graph construction method. Our results and comparison to other assemblers demonstrate that HyDA-Vista achieves the best assembly of E. coli before repeat resolution or scaffolding. Availability HyDA-Vista is freely available [1]. The code for constructing the maximal sequence landscape and choosing the optimal value of k for each read is also separately available on the website and could be incorporated into any genome assembler. PMID:25558875

  11. Microfossils in micrites from Serra da Bodoquena (MS), Brazil: taxonomy and paleoenvironmental implications.

    PubMed

    Utida, Giselle; Petri, Setembrino; Oliveira, Emiliano C; Boggiani, Paulo C

    2012-06-01

    Microfossils present in Quaternary micrites from Serra da Bodoquena, Mato Grosso do Sul State, Brazil, are here described for the first time. The studied taxa are: a) ostracods: Candona sp., Candonopsis sp., Cyclocypris sp., Cypria sp., Cypridopsis sp., Notodromas sp., Ilyocypris sp., Cyprideis sp., Wolburgiopsis cf. chinamuertensis (Musacchio 1970), Darwinula sp. and 5 morphotypes; b) microgastropod Acrobis sp., and c) Characeae remains and gyrogonites Chara sp.. The presence of these microfossils suggests clear-water shallow lacustrine paleoenvironments and the presence of aquatic vegetation. Similarities between microfossils and the living taxa suggest possible Holocene ages for these deposits, which is in accordance with previous C(14) dates. PMID:22499261

  12. Is the DA white dwarf 1910 + 047 a soft X-ray source?

    NASA Technical Reports Server (NTRS)

    Vennes, Stephane

    1990-01-01

    The possibility that the recently discovered DA white dwarf WD 1910 + 047 might be an Einstein soft X-ray source is studied, applying a complete model atmosphere analyis to both the optical and the soft X-ray data. It is found that the X-ray source in question is at least one order of magnitude too strong to be compatible with the estimated atmospheric parameters of the possible optical counterpart. The spatial coincidence between the two, however, remains extremely intriguing and has left us with the dilemma of accepting the relatively improbable coincidence of two unrelated objects or rejoicing over the discovery of a highly unusual one.

  13. The strainrange partitioning behavior of an advanced gas turbine disk alloy, AF2-1DA

    NASA Technical Reports Server (NTRS)

    Halford, G. R.; Nachtigall, A. J.

    1979-01-01

    The low-cycle, creep-fatigue characteristics of the advanced gas turbine disk alloy, AF2-1DA have been determined at 1400 F and are presented in terms of the method of strainrange partitioning (SRP). The mean stresses which develop in the PC and CP type SRP cycles at the lowest inelastic strainrange were observed to influence the cyclic lives to a greater extent than the creep effects and hence interfered with a conventional interpretation of the results by SRP. A procedure is proposed for dealing with the mean stress effects on life which is compatible with SRP.

  14. The strainrange partitioning behavior of an advanced gas turbine disk alloy, AF2-1DA

    NASA Technical Reports Server (NTRS)

    Halford, G. R.; Nachtigall, A. J.

    1979-01-01

    The low-cycle, creep-fatigue characteristics of the advanced gas turbine disk alloy, AF2-1DA have been determined at 1400 F and are presented in terms of the method of strainrange partitioning (SRP). The mean stresses which develop in the PC (tensile Plasticity reversed by compressive Creep) and CP (tensile Creep reversed by compressive Plasticity) type SRP cycles at the lowest inelastic strainrange were observed to influence the cyclic lives to a greater extent than the creep effects and hence interfered with a conventional interpretation of the results by SRP. A procedure is proposed for dealing with the mean stress effects on life which is compatible with SRP.

  15. Exacerbation of protracted-relapsing experimental allergic encephalomyelitis in DA rats by gluten-free diet.

    PubMed

    Di Marco, Roberto; Mangano, Katia; Quattrocchi, Cinzia; Amato, Filiberto; Nicoletti, Ferdinando; Buschard, Karsten

    2004-10-01

    The observation of neurological dysfunctions resembling multiple sclerosis (MS) seen clinically and/or by MRI in patients with celiac disease has focused attention on the possibility that cryptic gluten sensitivity may be involved in the pathogenesis of MS. Here we study the effects of a gluten-free diet on the course of protracted-relapsing EAE in DA rats, serving as a preclinical model of human MS. The data show not only that this nutritional approach failed to ameliorate development of the disease but rather that it exacerbated the course. PMID:15601316

  16. Angiotensin Converting Enzyme 90 kDa isoform: Biomarker for diagnosis of preeclampsia?

    PubMed

    Krauspenhar, Bruna; Sontag, Fernando; Ronchi, Fernanda A; Casarini, Dulce E; Poli-de-Figueiredo, Carlos Eduardo; Pinheiro da Costa, Bartira E

    2014-11-01

    Preeclampsia (PE), one of the leading gestational hypertensive diseases, is characterized by increased blood pressure (?140/90mmHg) and pathological proteinuria after 20weeks gestation. It is a complex, multifactorial syndrome with an unestablished etiology and cure. The search continues for a biomarker that could assist in the early prediction or diagnosis of PE, reducing the rate of maternal and fetal mortality. Based on the findings of Casarini et al. that suggest the 90kDa isoform of the Angiotensin Converting Enzyme (ACE) as a possible marker of hypertension, we hypothesized that this isoform may be present in pregnant women with PE, since they present a transient and spontaneous model of systemic arterial hypertension in pregnancy. We believe, therefore, that pregnant women with pure PE (PPE) express the ACE 90kDa isoform in urine, as well as having elevated isoform enzymatic activity, during pregnancy only. Postpartum, with the normalization of blood pressure, the protein isoform would no longer be expressed. Pregnant women with superimposed preeclampsia (SPE) would present the ACE 90kDa isoform both during and after the gestation period, and its enzymatic activity would remain high as they are chronically hypertensive. It is expected that normotensive pregnant women do not present this isoform in their urine as elevated blood pressure levels do not occur. Both normotensive and PPE affected pregnant women with a family history of hypertension, will possibly express the ACE 90kDa isoform before pregnancy and may become hypertensive, only after some years, through the influence of environmental factors and/or other diseases. If our hypothesis is confirmed, it will allow differentiation of PPE and SPE sooner than 12weeks postpartum, which is currently the estimated period for confirmation of the specific diagnosis. Furthermore, it could be an early biomarker for predicting the disease, enabling the physician to choose the best clinical management. In addition, it would minimize the use of other methods as the biological sample for obtaining the marker is urine, a practical and effective test with good reproducibility. Finally, test results would enable a greater understanding of the mechanisms involved in gestational hypertension. PMID:25257705

  17. Middle Paleolithic human remains from the Gruta da Oliveira (Torres Novas), Portugal.

    PubMed

    Trinkaus, Erik; Maki, Julia; Zilhão, João

    2007-10-01

    Ongoing excavations in the Middle Paleolithic levels at the Gruta da Oliveira, Portugal have yielded four fragmentary human remains, a manual phalanx and an ulna from levels 9 and 10, and a humerus and a tibia from levels 18 and 19. The first two remains date to approximately 39 ka 14C BP ( approximately 43.5 ka cal BP), whereas the latter two derive from earlier in oxygen isotope stage 3. The preserved portions of the phalanx, humerus, and tibia align them morphologically with the Neandertals. In addition, the Oliveira 4 tibial diaphysis shows evidence of carnivore (probably canid) gnawing. PMID:17632802

  18. Quadrupole Ion Mass Spectrometer for Masses of 2 to 50 Da

    NASA Technical Reports Server (NTRS)

    Helms, William; Griffin, Timothy P.; Ottens, Andrew; Harrison, Willard

    2005-01-01

    A customized quadrupole ion-trap mass spectrometer (QITMS) has been built to satisfy a need for a compact, rugged instrument for measuring small concentrations of hydrogen, helium, oxygen, and argon in a nitrogen atmosphere. This QITMS can also be used to perform quantitative analyses of other gases within its molecular-mass range, which is 2 to 50 daltons (Da). (More precisely, it can be used to perform quantitative analysis of gases that, when ionized, are characterized by m/Z ratios between 2 and 50, where m is the mass of an ion in daltons and Z is the number of fundamental electric charges on the ion.

  19. Orthosteric binding of ?-Da1a, a natural peptide of snake venom interacting selectively with the ?1A-adrenoceptor.

    PubMed

    Maïga, Arhamatoulaye; Merlin, Jon; Marcon, Elodie; Rouget, Céline; Larregola, Maud; Gilquin, Bernard; Fruchart-Gaillard, Carole; Lajeunesse, Evelyne; Marchetti, Charles; Lorphelin, Alain; Bellanger, Laurent; Summers, Roger J; Hutchinson, Dana S; Evans, Bronwyn A; Servent, Denis; Gilles, Nicolas

    2013-01-01

    ?-Da1a is a three-finger fold toxin from green mamba venom that is highly selective for the ?1A-adrenoceptor. This toxin has atypical pharmacological properties, including incomplete inhibition of (3)H-prazosin or (125)I-HEAT binding and insurmountable antagonist action. We aimed to clarify its mode of action at the ?1A-adrenoceptor. The affinity (pKi 9.26) and selectivity of ?-Da1a for the ?1A-adrenoceptor were confirmed by comparing binding to human adrenoceptors expressed in eukaryotic cells. Equilibrium and kinetic binding experiments were used to demonstrate that ?-Da1a, prazosin and HEAT compete at the ?1A-adrenoceptor. ?-Da1a did not affect the dissociation kinetics of (3)H-prazosin or (125)I-HEAT, and the IC50 of ?-Da1a, determined by competition experiments, increased linearly with the concentration of radioligands used, while the residual binding by ?-Da1a remained stable. The effect of ?-Da1a on agonist-stimulated Ca(2+) release was insurmountable in the presence of phenethylamine- or imidazoline-type agonists. Ten mutations in the orthosteric binding pocket of the ?1A-adrenoceptor were evaluated for alterations in ?-Da1a affinity. The D106(3.32)A and the S188(5.42)A/S192(5.46)A receptor mutations reduced toxin affinity moderately (6 and 7.6 times, respectively), while the F86(2.64)A, F288(6.51)A and F312(7.39)A mutations diminished it dramatically by 18- to 93-fold. In addition, residue F86(2.64) was identified as a key interaction point for (125)I-HEAT, as the variant F86(2.64)A induced a 23-fold reduction in HEAT affinity. Unlike the M1 muscarinic acetylcholine receptor toxin MT7, ?-Da1a interacts with the human ?1A-adrenoceptor orthosteric pocket and shares receptor interaction points with antagonist (F86(2.64), F288(6.51) and F312(7.39)) and agonist (F288(6.51) and F312(7.39)) ligands. Its selectivity for the ?1A-adrenoceptor may result, at least partly, from its interaction with the residue F86(2.64), which appears to be important also for HEAT binding. PMID:23935897

  20. The DA antagonist tiapride impairs context-related extinction learning in a novel context without affecting renewal

    PubMed Central

    Lissek, Silke; Glaubitz, Benjamin; Wolf, Oliver T.; Tegenthoff, Martin

    2015-01-01

    Renewal describes the recovery of an extinguished response if recall is tested in a context different from the extinction context. Behavioral studies demonstrated that attention to relevant context strengthens renewal. Neurotransmitters mediating attention and learning such as the dopaminergic (DA) system presumably modulate extinction learning and renewal. However, the role of DA for non-fear-based extinction learning and renewal in humans has not yet been investigated. This fMRI study investigated effects of DA-antagonism upon context-related extinction in a predictive learning task in which extinction occurred either in a novel (ABA) or an unchanged (AAA) context. The tiapride-treated group (TIA) showed significantly impaired ABA extinction learning and a significant within-group difference between ABA and AAA extinction, compared to placebo (PLAC). Groups did not differ in their level of ABA renewal. In ABA extinction, TIA showed reduced activation in dlPFC and OFC, hippocampus, and temporal regions. Across groups, activation in PFC and hippocampus correlated negatively with ABA extinction errors. Results suggest that in context-related extinction learning DA in PFC and hippocampus is involved in readjusting the cue-outcome relationship in the presence of a novel context. However, relating context to the appropriate association during recall does not appear to rely exclusively on DA signaling. PMID:26388752

  1. Agarose and Polyacrylamide Gel Electrophoresis Methods for Molecular Mass Analysis of 5–500 kDa Hyaluronan

    PubMed Central

    Bhilocha, Shardul; Amin, Ripal; Pandya, Monika; Yuan, Han; Tank, Mihir; LoBello, Jaclyn; Shytuhina, Anastasia; Wang, Wenlan; Wisniewski, Hans-Georg; de la Motte, Carol; Cowman, Mary K.

    2011-01-01

    Agarose and polyacrylamide gel electrophoresis systems for the molecular mass-dependent separation of hyaluronan (HA) in the size range of approximately 5–500 kDa have been investigated. For agarose-based systems, the suitability of different agarose types, agarose concentrations, and buffers systems were determined. Using chemoenzymatically synthesized HA standards of low polydispersity, the molecular mass range was determined for each gel composition, over which the relationship between HA mobility and logarithm of the molecular mass was linear. Excellent linear calibration was obtained for HA molecular mass as low as approximately 9 kDa in agarose gels. For higher resolution separation, and for extension to molecular masses as low as approximately 5 kDa, gradient polyacrylamide gels were superior. Densitometric scanning of stained gels allowed analysis of the range of molecular masses present in a sample, and calculation of weight-average and number-average values. The methods were validated for polydisperse HA samples with viscosity-average molecular masses of 112, 59, 37, and 22 kDa, at sample loads of 0.5 µg (for polyacrylamide) to 2.5 µg (for agarose). Use of the methods for electrophoretic mobility shift assays was demonstrated for binding of the HA-binding region of aggrecan (recombinant human aggrecan G1-IGD-G2 domains) to a 150 kDa HA standard. PMID:21684248

  2. PanDA: A New Paradigm for Distributed Computing in HEP Through the Lens of ATLAS and other Experiments

    E-print Network

    De, K; The ATLAS collaboration; Maeno, T; Nilsson, P; Wenaus, T

    2014-01-01

    Experiments at the Large Hadron Collider (LHC) face unprecedented computing challenges. Heterogeneous resources are distributed worldwide, thousands of physicists analyzing the data need remote access to hundreds of computing sites, the volume of processed data is beyond the exabyte scale, and data processing requires more than a billion hours of computing usage per year. The PanDA (Production and Distributed Analysis) system was developed to meet the scale and complexity of LHC distributed computing for the ATLAS experiment. In the process, the old batch job paradigm of computing in HEP was discarded in favor of a far more flexible and scalable model. The success of PanDA in ATLAS is leading to widespread adoption and testing by other experiments. PanDA is the first exascale workload management system in HEP, already operating at a million computing jobs per day, and processing over an exabyte of data in 2013. We will describe the design and implementation of PanDA, present data on the performance of PanDA a...

  3. Project Da Vinci: a study of long-range air pollution using a balloon-borne Lagrangian measurement platform. Volume 2. Reports of participants in Da Vinci 1. Final report

    SciTech Connect

    Zak, B.D.

    1981-05-01

    Understanding long-range air pollution is becoming increasingly important for the development of cost-effective air-quality control strategies. Project Da Vinci was the beginning of a continuing effort at Sandia to address the need to study long-range air pollution. It consisted of a series of three instrumented, manned balloon flights to study the lower atmosphere in a Lagrangian frame of reference. These experiments gathered information on gases and aerosols, radiation, electrical fields, atmospheric structure, turbulence, diffusion, mesoscale motions, and their interrelationship. Volume II is a collection of the reports from researchers involved in Da Vinci I.

  4. The 55?kDa tissue transglutaminase cross-linking active isoform TG induces cell death.

    PubMed

    Fraij, Bassam M

    2015-09-01

    Transamidations are calcium-dependent reactions catalyzed by transglutaminase enzymes. Tissue transglutaminase (TG2 or TGC) is a multifunctional protein with a controversial role in apoptosis. The cross-linking function of transglutaminase enzymes has been shown to play a role in cell death. Human breast cancer cell lines (MCF7 and T47D), which express low endogenous levels of transglutaminase, were transiently transfected with the cross-linking 55?kDa active TG isoform or its precursor the 80?kDa full-length TGC. The increased frequency of apoptosis correlated with the increase in transglutaminase expression and the highest rates of apoptosis were found in cells transfected with the potent TG isoform as compared to the full length TGC. The calcium ionophores A231827 and maitotoxin, which are known to induce transamidation, were found to promote apoptosis, whereas cystamine, an active transglutaminase inhibitor, blocked apoptosis due to the over-expression of the active TG isoform. This is the first time that TG has been used in cellular transfections and the results presented show that TG is a potent inducer of cell death. This finding may help to clarify the conflicting functions of TG in the induction of cell death. The TG-dependent irreversible cross-linking of intracellular proteins, a function previously assigned to TGC, represents an important biochemical event in the induction of the structural changes present in cells during apoptosis. PMID:24464646

  5. The uncatchable smile in Leonardo da Vinci's La Bella Principessa portrait.

    PubMed

    Soranzo, Alessandro; Newberry, Michelle

    2015-08-01

    A portrait of uncertain origin recently came to light which, after extensive research and examination, was shown to be that rarest of things: a newly discovered Leonardo da Vinci painting entitled La Bella Principessa. This research presents a new illusion which is similar to that identified in the Mona Lisa; La Bella Principessa's mouth appears to change slant depending on both the Viewing Distance and the Level of Blur applied to a digital version of the portrait. Through a series of psychophysics experiments, it was found that a perceived change in the slant of the La Bella Principessa's mouth influences her expression of contentment thus generating an illusion that we have coined the "uncatchable smile". The elusive quality of the Mona Lisa's smile has been previously reported (Science, 290 (2000) 1299) and so the existence of a similar illusion in a portrait painted prior to the Mona Lisa becomes more interesting. The question remains whether Leonardo da Vinci intended this illusion. In any case, it can be argued that the ambiguity created adds to the portrait's allure. PMID:26049039

  6. Determinação da composição química em nebulosas planetárias na direção do anticentro galáctico

    NASA Astrophysics Data System (ADS)

    Costa, R. D. D.; Uchida, M. M. M.; Maciel, W. J.

    2003-08-01

    Existe um gradiente radial de abundâncias no disco galáctico, cujo comportamento é razoavelmente bem conhecido para distâncias galactocêntricas entre 3 e 10 kpc. Foi obtido a partir de resultados derivados de nebulosas planetárias, regiões HII e estrelas, como as estrelas quentes de tipo O, B e aglomerados abertos. Com o objetivo de investigar o comportamento deste gradiente radial na região externa do disco, conhecida como anticentro galáctico, reportamos aqui os resultados finais da análise de uma amostra de nebulosas planetárias na direção do anticentro, observadas no LNA e no ESO entre 1995 e 2000. O uso de nebulosas planetárias permite o cálculo das abundâncias de elementos traçadores da evolução química do disco como oxigênio, argônio e neônio com o uso de técnicas de espectroscopia nebular. Os resultados indicam uma distribuição de abundâncias distinta daquela encontrada na vizinhança solar, mostrando que o gradiente radial diminui sensivelmente para distâncias galactocêntricas maiores que 10 kpc. Este resultado está de acordo com os mais recentes modelos de evolução química do disco, que prevêem uma diminuição ou mesmo um desaparecimento do gradiente radial no bordo externo do disco galáctico. (FAPESP/CNPq)

  7. Development of a benthic multimetric index for the Serra da Bocaina bioregion in Southeast Brazil.

    PubMed

    Baptista, D F; Henriques-Oliveira, A L; Oliveira, R B S; Mugnai, R; Nessimian, J L; Buss, D F

    2013-08-01

    Brazil faces a challenge to develop biomonitoring tools to be used in water quality assessment programs, but few multimetric indices were developed so far. This study is part of an effort to test and implement programs using benthic macroinvertebrates as bioindicators in Rio de Janeiro State. Our aim was first to test the Multimetric Index for Serra dos Órgãos (SOMI) for a different area--Serra da Bocaina (SB)--in the same ecoregion. We sampled 27 streams of different sizes and altitudes in the SB region. Despite the environmental similarities, results indicated biological differences between reference sites of the two regions. Considering these differences, we decided to develop an index specific for the SB region, the Serra da Bocaina Multimetric Index (MISB). We tested twenty-two metrics for sensitivity to impairment and redundancy, and six metrics were considered valid to integrate the MISB: Family Richness, Trichoptera Richness, % Coleoptera, % Diptera, IBE-IOC index, EPT / Chironomidae ratio. A test of the MISB in eleven sites indicated it was more related to land-use and water physico-chemical parameters than with altitude or stream width, being a useful tool for the monitoring and assessment of streams in the bioregion. PMID:24212698

  8. PanDA: Exascale Federation of Resources for the ATLAS Experiment at the LHC

    E-print Network

    Barreiro Megino, Fernando Harald; The ATLAS collaboration; De, Kaushik; Hover, John; Klimentov, Alexei; Maeno, Tadashi; Nilsson, Paul; Oleynik, Danila; Padolski, Siarhei; Panitkin, Sergey; Petrosyan, Artem; Wenaus, Torre

    2015-01-01

    After a scheduled maintenance and upgrade period, the world’s largest and most powerful machine - the Large Hadron Collider(LHC) - is about to enter its second run at unprecedented energies. In order to exploit the scientific potential of the machine, the experiments at the LHC face computational challenges with enormous data volumes that need to be analysed by thousand of physics users and compared to simulated data. Given diverse funding constraints, the computational resources for the LHC have been deployed in a worldwide mesh of data centres, connected to each other through Grid technologies. The PanDA (Production and Distributed Analysis) system was developed in 2005 for the ATLAS experiment on top of this heterogeneous infrastructure to seamlessly integrate the computational resources and give the users the feeling of a unique system. Since its origins, PanDA has evolved together with upcoming computing paradigms in and outside HEP, such as changes in the networking model, Cloud Computing and HPC. It ...

  9. VaccineDA: Prediction, design and genome-wide screening of oligodeoxynucleotide-based vaccine adjuvants

    PubMed Central

    Nagpal, Gandharva; Gupta, Sudheer; Chaudhary, Kumardeep; Kumar Dhanda, Sandeep; Prakash, Satya; Raghava, Gajendra P. S.

    2015-01-01

    Immunomodulatory oligodeoxynucleotides (IMODNs) are the short DNA sequences that activate the innate immune system via toll-like receptor 9. These sequences predominantly contain unmethylated CpG motifs. In this work, we describe VaccineDA (Vaccine DNA adjuvants), a web-based resource developed to design IMODN-based vaccine adjuvants. We collected and analyzed 2193 experimentally validated IMODNs obtained from the literature. Certain types of nucleotides (e.g., T, GT, TC, TT, CGT, TCG, TTT) are dominant in IMODNs. Based on these observations, we developed support vector machine-based models to predict IMODNs using various compositions. The developed models achieved the maximum Matthews Correlation Coefficient (MCC) of 0.75 with an accuracy of 87.57% using the pentanucleotide composition. The integration of motif information further improved the performance of our model from the MCC of 0.75 to 0.77. Similarly, models were developed to predict palindromic IMODNs and attained a maximum MCC of 0.84 with the accuracy of 91.94%. These models were evaluated using a five-fold cross-validation technique as well as validated on an independent dataset. The models developed in this study were integrated into VaccineDA to provide a wide range of services that facilitate the design of DNA-based vaccine adjuvants (http://crdd.osdd.net/raghava/vaccineda/). PMID:26212482

  10. Observações espectroscópicas da candidata a pós-AGB IRAS 19386+0155

    NASA Astrophysics Data System (ADS)

    Lorenz-Martins, S.; Pereira, C. B.

    2003-08-01

    Nesse trabalho apresentamos a análise fotosférica da estrela candidata a pós-AGB IRAS 19386+0155. Com os dados obtidos no espectrógrafo FEROS foram determinados os parâmetros atmosféricos e abundâncias fotosféricas utilizando o código MOOG. A análise do espectro mostrou que IRAS 19386+0155 possui os seguintes parâmetros atmosféricos : Teff = 6800K, log g = 1.4, [M/H] = -1.5 e Vt = 8.4 km/s. O padrão de abundância obtido para os elementos mais leves (Carbono, Nitrogênio e Oxigênio) e elementos a (Magnésio, Silício e Cálcio) foi inferior ao solar (log C = 7.74, log N = 7.28, Log O = 8.43, log Mg = 7.14, log Si = 7.54 e log Ca = 5.91). Uma inspeção visual do espectro ISO deste objeto revela a presença de poeira fria na forma de silicatos cristalinos. Embora as bandas mais marcantes de silicatos amorfos (em 10 mm e 18mm) não sejam observadas, a emissão em 21 mm, presente em algumas pós-AGBs também não está presente. O espectro ISO parece revelar um meio rico em oxigênio, mas a forma da distribuição de energia no infravermelho não obedece ao padrão apresentado por outras pós-AGBs. Nossos resultados nos levam a sugerir que IRAS 19386+0155 talvez faça parte de um sistema binário, uma vez que outras pós-AGBs que são membros de sistemas binários apresentam padrão de abundância semelhante.

  11. Leonardo da Vinci and Andreas Vesalius; the shoulder girdle and the spine, a comparison.

    PubMed

    Ganseman, Y; Broos, P

    2008-01-01

    Leonardo Da Vinci and Andreas Vesalius were two important renaissance persons; Vesalius was a surgeon-anatomist who delivered innovative work on the study of the human body, Leonardo da Vinci was an artist who delivered strikingly accurate and beautiful drawings on the human body. Below we compare both masters with regard to their knowledge of the working of the muscles, their method and system of dissection and their system and presentation of the drawings. The investigation consisted of a comparison between both anatomists, in particular concerning their study on the shoulder girdle and spine, by reviewing their original work as well as already existing literature on this subject. The investigation led to the conclusion that the drawings mentioned meant a change in history, and were of high quality, centuries ahead of their time. Both were anatomists, both were revolutionary, only one changed history at the moment itself, while the other changed history centuries later. Leonardo has made beautiful drawings that are at a match with the drawings of today or are even better. Vesalius set the start for medicine as a science as it is until this day. Their lives differed as strongly as their impact. In the light of their time, the achievement they made was extraordinary. PMID:18807610

  12. Development of noSQL data storage for the ATLAS PanDA Monitoring System

    NASA Astrophysics Data System (ADS)

    Ito, H.; Potekhin, M.; Wenaus, T.

    2012-12-01

    For several years the PanDA Workload Management System has been the basis for distributed production and analysis for the ATLAS experiment at the LHC. Since the start of data taking PanDA usage has ramped up steadily, typically exceeding 500k completed jobs/day by June 2011. The associated monitoring data volume has been rising as well, to levels that present a new set of challenges in the areas of database scalability and monitoring system performance and efficiency. These challenges are being met with an R&D effort aimed at implementing a scalable and efficient monitoring data storage based on a noSQL solution (Cassandra). We present our motivations for using this technology, as well as data design and the techniques used for efficient indexing of the data. We also discuss the hardware requirements as they were determined by testing with actual data and realistic rate of queries. In conclusion, we present our experience with operating a Cassandra cluster over an extended period of time and with data load adequate for planned application.

  13. Crystal Structure of the 25 kDa Subunit of Human Cleavage Factor I{m}

    SciTech Connect

    Coseno,M.; Martin, G.; Berger, C.; Gilmartin, G.; Keller, W.; Doublie, S.

    2008-01-01

    Cleavage factor Im is an essential component of the pre-messenger RNA 3'-end processing machinery in higher eukaryotes, participating in both the polyadenylation and cleavage steps. Cleavage factor Im is an oligomer composed of a small 25 kDa subunit (CF Im25) and a variable larger subunit of either 59, 68 or 72 kDa. The small subunit also interacts with RNA, poly(A) polymerase, and the nuclear poly(A)-binding protein. These protein-protein interactions are thought to be facilitated by the Nudix domain of CF Im25, a hydrolase motif with a characteristic {alpha}/{beta}/{alpha} fold and a conserved catalytic sequence or Nudix box. We present here the crystal structures of human CF Im25 in its free and diadenosine tetraphosphate (Ap4A) bound forms at 1.85 and 1.80 Angstroms, respectively. CF Im25 crystallizes as a dimer and presents the classical Nudix fold. Results from crystallographic and biochemical experiments suggest that CF Im25 makes use of its Nudix fold to bind but not hydrolyze ATP and Ap4A. The complex and apo protein structures provide insight into the active oligomeric state of CF Im and suggest a possible role of nucleotide binding in either the polyadenylation and/or cleavage steps of pre-messenger RNA 3'-end processing.

  14. Generation of a multi-band spectrum using a D/A converter for an RF-knockout system

    NASA Astrophysics Data System (ADS)

    Shinkai, Akio; Ishikawa, Soichiro; Nakanishi, Tetsuya

    2015-01-01

    A method of generating a multi-band spectrum is proposed using a digital-to-analog (D/A) converter. The multi-band spectrum is useful for the slow-beam-extraction from a synchrotron using the method of radio frequency (RF)-knockout. Data for the spectrum are calculated in advance to be saved in the memory of a D/A converter, and are output synchronized with external clocks. An experiment showed that a multi-band spectrum of 10 bands could be generated with a total bandwidth of about 16.4 MHz and each bandwidth less than 45 kHz. Beam simulation with this method showed that an RF signal from a D/A converter could be effectively used for the control of uniform spill structure.

  15. gLExec and MyProxy integration in the ATLAS/OSG PanDA workload management system

    NASA Astrophysics Data System (ADS)

    Caballero, J.; Hover, J.; Litmaath, M.; Maeno, T.; Nilsson, P.; Potekhin, M.; Wenaus, T.; Zhao, X.

    2010-04-01

    Worker nodes on the grid exhibit great diversity, making it difficult to offer uniform processing resources. A pilot job architecture, which probes the environment on the remote worker node before pulling down a payload job, can help. Pilot jobs become smart wrappers, preparing an appropriate environment for job execution and providing logging and monitoring capabilities. PanDA (Production and Distributed Analysis), an ATLAS and OSG workload management system, follows this design. However, in the simplest (and most efficient) pilot submission approach of identical pilots carrying the same identifying grid proxy, end-user accounting by the site can only be done with application-level information (PanDA maintains its own end-user accounting), and end-user jobs run with the identity and privileges of the proxy carried by the pilots, which may be seen as a security risk. To address these issues, we have enabled PanDA to use gLExec, a tool provided by EGEE which runs payload jobs under an end-user's identity. End-user proxies are pre-staged in a credential caching service, MyProxy, and the information needed by the pilots to access them is stored in the PanDA DB. gLExec then extracts from the user's proxy the proper identity under which to run. We describe the deployment, installation, and configuration of gLExec, and how PanDA components have been augmented to use it. We describe how difficulties were overcome, and how security risks have been mitigated. Results are presented from OSG and EGEE Grid environments performing ATLAS analysis using PanDA and gLExec.

  16. Membrane-associated 41-kDa GTP-binding protein in collagen-induced platelet activation

    SciTech Connect

    Walker, G.; Bourguignon, L.Y. )

    1990-08-01

    Initially we established that the binding of collagen to human blood platelets stimulates both the rapid loss of PIP2 and the generation of inositol-4,5-bisphosphate (IP2) and inositol-1,4,5-triphosphate (IP3). These results indicate that the binding of collagen stimulates inositol phospholipid-specific phospholipase C during platelet activation. The fact that GTP or GTP-gamma-S augments, and pertussis toxin inhibits, collagen-induced IP3 formation suggests that a GTP-binding protein or (or proteins) may be directly involved in the regulation of phospholipase C-mediated phosphoinositide turnover in human platelets. We have used several complementary techniques to isolate and characterize a platelet 41-kDa polypeptide (or polypeptides) that has a number of structural and functional similarities to the regulatory alpha i subunit of the GTP-binding proteins isolated from bovine brain. This 41-kDa polypeptide (or polypeptides) is found to be closely associated with at least four membrane glycoproteins (e.g., gp180, gp110, gp95, and gp75) in a 330-kDa complex that can be dissociated by treatment with high salt plus urea. Most important, we have demonstrated that antilymphoma 41-kDa (alpha i subunit of GTP-binding proteins) antibody cross-reacts with the platelet 41-kDa protein (or proteins) and the alpha i subunit of bovine brain Gi alpha proteins, and blocks GTP/collagen-induced IP3 formation. These data provide strong evidence that the 41-kDa platelet GTP-binding protein (or proteins) is directly involved in collagen-induced signal transduction during platelet activation.

  17. Observing the result of external magnetic field with nonextensivity on DA waves for two temperature electrons in a dusty plasmas

    NASA Astrophysics Data System (ADS)

    Zobaer, M. S.; Roy, N.; Mamun, A. A.

    2014-03-01

    This theoretical investigation has been made on dust-acoustic (DA) waves containing nonextensivity of electrons being two different temperatures, negatively charged dust grains, and Maxwellian ions. The Zakharov-Kuznetsov (Z-K) equation has been derived and numerically solved to analysis the basis features. It is observed that the characteristics of the DA solitary waves (DASWs) are significantly modified by the external magnetic field with the different temperatures for electrons followed by the nonextensive distribution. The results obtained from this analysis can be employed in understanding the nature of plasma waves both in laboratory and space plasma system.

  18. L151-81A/B - A unique white dwarf binary with DB and DA components

    NASA Technical Reports Server (NTRS)

    Oswalt, Terry D.; Hintzen, Paul M.; Liebert, James W.; Sion, Edward M.

    1988-01-01

    Spectroscopic observations of the wide binary L151-81A/B reveal that both components are white dwarfs with spectral types DB3 and DA4, the first such binary identified in a comprehensive survey of Luyten and Giclas common proper motion pairs. Assuming log g = 8, measurements of the helium line profiles in the DB primary yield Teff = 16,000 + or - 2,000, while the hydrogen profiles for the DA companion yield Teff =12,000 + or - 2,000. The existence of a helium-rich/hydrogen-rich degenerate pair offers several interesting tests of theoretical white dwarf formation channels and surface abundance evolution.

  19. 1 Interferenza prodotta da due fenditure 1 L'intensit`a sullo schermo di osservazione `e data, nell'approssimazione detta

    E-print Network

    Spagnolo, Filippo

    presente nella descrizione basata sull'elettromagnetismo. Infatti, la distribuzione dell'energia nello l'energia sia diversa da zero (figura 2), la teoria non `e in grado di specificare da dove l'energia provenga. La teoria non `e quindi in grado di specificare quale sia il percorso dell'energia tra la

  20. I Workshop de Tec. da Inf. Apl. ao Meio Ambiente -CBComp 2003 Sis. de Apoio Tomada de Deciso DESIGN DE UM SISTEMA DE SUPORTE DECISO BASEADO

    E-print Network

    Cengarle, María Victoria

    I Workshop de Tec. da Inf. Apl. ao Meio Ambiente - CBComp 2003 Sis. de Apoio à Tomada de Decisão Workshop de Tec. da Inf. Apl. ao Meio Ambiente - CBComp 2003 Sis. de Apoio à Tomada de Decisão 1895 de conhecimento com base em modelos fornecem meios para tornar disponível o conhecimento de

  1. In para totale...una cosa da panico...sulla lingua dei giovani in Italia (In para totale...una cosa da panico...The Language of Young People in Italy).

    ERIC Educational Resources Information Center

    Marcato, Carla

    1997-01-01

    Describes and analyzes the language of young people in Italy today. Particular focus is on the expressions using "para" (e.g., "in para totale" = to be very bored or worried) and the phrase "una cosa da panico" (something terrible or its opposite something wonderful). (CFM)

  2. DaVIE: Database for the Visualization and Integration of Epigenetic data.

    PubMed

    Fejes, Anthony P; Jones, Meaghan J; Kobor, Michael S

    2014-01-01

    One of the challenges in the analysis of large data sets, particularly in a population-based setting, is the ability to perform comparisons across projects. This has to be done in such a way that the integrity of each individual project is maintained, while ensuring that the data are comparable across projects. These issues are beginning to be observed in human DNA methylation studies, as the Illumina 450k platform and next generation sequencing-based assays grow in popularity and decrease in price. This increase in productivity is enabling new insights into epigenetics, but also requires the development of pipelines and software capable of handling the large volumes of data. The specific problems inherent in creating a platform for the storage, comparison, integration, and visualization of DNA methylation data include data storage, algorithm efficiency and ability to interpret the results to derive biological meaning from them. Databases provide a ready-made solution to these issues, but as yet no tools exist that that leverage these advantages while providing an intuitive user interface for interpreting results in a genomic context. We have addressed this void by integrating a database to store DNA methylation data with a web interface to query and visualize the database and a set of libraries for more complex analysis. The resulting platform is called DaVIE: Database for the Visualization and Integration of Epigenetics data. DaVIE can use data culled from a variety of sources, and the web interface includes the ability to group samples by sub-type, compare multiple projects and visualize genomic features in relation to sites of interest. We have used DaVIE to identify patterns of DNA methylation in specific projects and across different projects, identify outlier samples, and cross-check differentially methylated CpG sites identified in specific projects across large numbers of samples. A demonstration server has been setup using GEO data at http://echelon.cmmt.ubc.ca/dbaccess/, with login "guest" and password "guest." Groups may download and install their own version of the server following the instructions on the project's wiki. PMID:25278960

  3. DaVIE: Database for the Visualization and Integration of Epigenetic data

    PubMed Central

    Fejes, Anthony P.; Jones, Meaghan J.; Kobor, Michael S.

    2014-01-01

    One of the challenges in the analysis of large data sets, particularly in a population-based setting, is the ability to perform comparisons across projects. This has to be done in such a way that the integrity of each individual project is maintained, while ensuring that the data are comparable across projects. These issues are beginning to be observed in human DNA methylation studies, as the Illumina 450k platform and next generation sequencing-based assays grow in popularity and decrease in price. This increase in productivity is enabling new insights into epigenetics, but also requires the development of pipelines and software capable of handling the large volumes of data. The specific problems inherent in creating a platform for the storage, comparison, integration, and visualization of DNA methylation data include data storage, algorithm efficiency and ability to interpret the results to derive biological meaning from them. Databases provide a ready-made solution to these issues, but as yet no tools exist that that leverage these advantages while providing an intuitive user interface for interpreting results in a genomic context. We have addressed this void by integrating a database to store DNA methylation data with a web interface to query and visualize the database and a set of libraries for more complex analysis. The resulting platform is called DaVIE: Database for the Visualization and Integration of Epigenetics data. DaVIE can use data culled from a variety of sources, and the web interface includes the ability to group samples by sub-type, compare multiple projects and visualize genomic features in relation to sites of interest. We have used DaVIE to identify patterns of DNA methylation in specific projects and across different projects, identify outlier samples, and cross-check differentially methylated CpG sites identified in specific projects across large numbers of samples. A demonstration server has been setup using GEO data at http://echelon.cmmt.ubc.ca/dbaccess/, with login “guest” and password “guest.” Groups may download and install their own version of the server following the instructions on the project's wiki. PMID:25278960

  4. A 58-kDa resident protein of the cis Golgi cisterna is not terminally glycosylated.

    PubMed

    Hendricks, L C; Gabel, C A; Suh, K; Farquhar, M G

    1991-09-15

    A 58-kDa Golgi protein (gp58) was previously identified and found to be concentrated in cis Golgi cisternae in several cell types (Saraste, J., Palade, G.E., and Farquhar, M.G. (1987) J. Cell Biol. 105, 2021-2029). In this study the protein was partially purified from rat pancreas and mouse myeloma cells in order to characterize its oligosaccharides. It migrated on sodium dodecyl sulfate-polyacrylamide gels as a 57-58-kDa doublet under reducing conditions or as a single approximately 116-kDa band under nonreducing conditions. Pancreatic gp58 was susceptible to alpha-N-acetylgalactosaminidase digestion and it bound concanavalin A, Helix pomatia, Dolichos biflorus, soybean agglutinin, and Bauhinia purpurea lectins, but not Ricinus communis agglutinin or lectins from Griffonia simplicifolia-1, Arachis hypogaea, and Limulus polyphemus. It bound Ricinus communis agglutinin after galactosylation with GlcNAc galactosyltransferase. These data demonstrate that pancreatic p58 contains immature N-linked moieties with nonreducing terminal GlcNAc residues as well as the initiating GalNAc of O-linked glycoproteins. Myeloma gp58 was sensitive to endo-beta-N-acetylglucosaminidase H, and oligosaccharide analysis of its [3H]glucosamine-labeled glycopeptides indicated that it also contained immature N-linked glycans. Some of the latter consist of high mannose chains (high affinity for concanavalin A, endo-beta-N-acetylglucosaminidase H-sensitive), but the predominant (95%) species are neutral tri- or tetraantennary N-linked chains containing GlcNAc (no binding to concanavalin A). Glycopeptides from biosynthetically labeled myeloma cells did not contain detectable base labile oligosaccharides, indicating that unlike pancreatic p58, myeloma gp58 may not be an O-linked glycoprotein. Neither pancreatic nor myeloma gp58 contained terminally processed oligosaccharides, indicating that gp58 has not been modified by trans-Golgi glycosyltransferases. Thus, the oligosaccharide content of gp58 is consistent with the assumption that this protein is retained in the cis Golgi cisternae during biosynthesis instead of being transported across the Golgi stacks and targeted back to the cis Golgi from the trans side. PMID:1894639

  5. Micromorphology of selected relict slope deposits from Serra da Estrela, Portugal

    NASA Astrophysics Data System (ADS)

    Nieuwendam, Alexandre; Vieira, Gonçalo; Schaefer, Carlos

    2013-04-01

    Serra da Estrela is the highest mountain in Portugal (1,993 m ASL) and part of the Iberian Central Cordillera. The mountain has a strong relief and a lithological diversity with several types of granitoids and metasediments. Most of the western plateau area was glaciated during the Last Glacial Maximum and its morphology is dominated by glacial landforms. Vieira (2004) produced a detailed geomorphological map of Serra da Estrela and described several sites showing stratified slope, head and debris-flow deposits. Based on the geomorphological analysis of the relationships between glacial and periglacial evidence, a first relative chronology was presented. However, a detailed and systematical sedimentological analysis has not been conducted before and absolute ages are also lacking. Micromorphology analysis has proven to be of considerable value in the interpretation of mountain soils and sediments. Such interpretation depends on identifying diagnostic features, indicating factors as the presence or absence of permafrost, thickness of the active layer, ice segregation and the operation of processes of mass-wasting. In this study, micromorphology was used to answer questions concerning the composition, structure, origin and depositional processes of relict slope deposits. Micromorphology allowed a systematic description of the physical characteristics of the sediments. Lamination and sorting, when preserved, are good evidence for overland flow. Features due to deformation (folds, boudins, coatings and tails due to the rotation of clasts) are associated with sliding. Other mass-movements such as debris flows, earth flows, and to a certain extent, dry grain flows may be characterized by similar microscopic facies, typically a poorly sorted, porphyric material. Porosity gives evidence for both liquefaction (debris flows) and frost-induced mass-movement (solifluction). The relict slope deposits of the Serra da Estrela show an increase in cryogenic micromorphological features with altitude. Above 1100-1200 m, solifluction microstructures become frequent and very well-developed, evidencing frost-induced mass movement. Below this altitude solifluction processes were less frequently observed, and with poorly developed microfeatures. Debris-flow and run-off processes occur in a wider altitudinal range and are controlled by local topographical and geomorphological conditions.

  6. An Active 32-kDa Cathepsin L Is Secreted Directly from HT 1080 Fibrosarcoma Cells and Not via Lysosomal Exocytosis

    PubMed Central

    Hashimoto, Yoko; Kondo, Chihiro; Katunuma, Nobuhiko

    2015-01-01

    Cathepsin L [EC 3.4.22.15] is secreted via lysosomal exocytosis by several types of cancer cells, including prostate and breast cancer cells. We previously reported that human cultured fibrosarcoma (HT 1080) cells secrete cathepsin L into the medium; this secreted cathepsin is 10-times more active than intracellular cathepsin. This increased activity was attributed to the presence of a 32-kDa cathepsin L in the medium. The aim of this study was to examine how this active 32-kDa cathepsin L is secreted into the medium. To this end, we compared the secreted active 32-kDa cathepsin L with lysosomal cathepsin L by using a novel gelatin zymography technique that employs leupeptin. We also examined the glycosylation and phosphorylation status of the proteins by using the enzymes endoglycosidase H [EC 3.2.1.96] and alkaline phosphatase [EC 3.1.3.1]. Strong active bands corresponding to the 32-kDa and 34-kDa cathepsin L forms were detected in the medium and lysosomes, respectively. The cell extract exhibited strong active bands for both forms. Moreover, both forms were adsorbed onto a concanavalin A-agarose column. The core protein domain of both forms had the same molecular mass of 30 kDa. The 32-kDa cathepsin L was phosphorylated, while the 34-kDa lysosomal form was dephosphorylated, perhaps because of the lysosomal marker enzyme, acid phosphatase. These results suggest that the active 32-kDa form does not enter the lysosomes. In conclusion, our results indicate that the active 32-kDa cathepsin L is secreted directly from the HT 1080 cells and not via lysosomal exocytosis. PMID:26674348

  7. A NEW TIMESCALE FOR PERIOD CHANGE IN THE PULSATING DA WHITE DWARF WD 0111+0018

    SciTech Connect

    Hermes, J. J.; Montgomery, M. H.; Winget, D. E.; Mullally, Fergal; Bischoff-Kim, A.

    2013-03-20

    We report the most rapid rate of period change measured to date for a pulsating DA (hydrogen atmosphere) white dwarf (WD), observed in the 292.9 s mode of WD 0111+0018. The observed period change, faster than 10{sup -12} s s{sup -1}, exceeds by more than two orders of magnitude the expected rate from cooling alone for this class of slow and simply evolving pulsating WDs. This result indicates the presence of an additional timescale for period evolution in these pulsating objects. We also measure the rates of period change of nonlinear combination frequencies and show that they share the evolutionary characteristics of their parent modes, confirming that these combination frequencies are not independent modes but rather artifacts of some nonlinear distortion in the outer layers of the star.

  8. First Results of the VLBI Experiment on Radar Location of the Asteroid 2012 DA14

    NASA Astrophysics Data System (ADS)

    Nechaeva, M.; Antipenko, A.; Bezrukov, D.; Bezrukovs, Vl.; Dementjev, A.; Dugin, N.; Jekabsons, N.; Khutornoy, R.; Klapers, M.; Konovalenko, A.; Kulishenko, V.; Nabatov, A.; Nesteruk, V.; Pupillo, G.; Reznichenko, A.; Salerno, E.; Shmeld, I.; Skirmante, K.; Tikhomirov, Yu.; Voytyuk, V.

    An international VLBI experiment on radio location of the asteroid 2012 DA14 was organized on 2013 February 15--16, during its flyby close to Earth. The purpose of observations was to investigate and specify orbital parameters of the asteroid, as well as to evaluate its rotation period and other characteristics. The irradiation of the asteroid was performed by the RT-70 transmitter at Evpatoria (Crimea, Ukraine), while the reflected signals were successfully accepted by the two 32 m radio telescopes at Medicina (Bologna, Italy) and Irbene (Ventspils, Latvia). Processing and interpretation of the data were performed both in the Radiophysical Research Institute and in the Ventspils International Radio Astronomy Center. The first results of this experiment are presented and discussed.

  9. da Vinci fluids, catch-up dynamics and dense granular flow.

    PubMed

    Blumenfeld, R; Edwards, S F; Schwartz, M

    2010-08-01

    We introduce and study a da Vinci fluid, a fluid whose dissipation is dominated by solid friction. We analyse the flow rheology of a discrete model and then coarse-grain it to the continuum. We find that the model gives rise to behaviour that is characteristic of dense granular fluids. In particular, it leads to plug flow. We analyse the nucleation mechanism of plugs and their development. We find that plug boundaries generically expand and we calculate the growth rate of plug regions. In systems whose internal effective dynamic and static friction coefficients are relatively uniform we find that the linear size of plug regions grows as (time)¹(/)³ . The suitability of the model to granular materials is discussed. PMID:20668906

  10. Microbiological Analysis of Surfaces of Leonardo Da Vinci's Atlantic Codex: Biodeterioration Risk

    PubMed Central

    Moroni, Catia; Pasquariello, Giovanna; Maggi, Oriana

    2014-01-01

    Following the discovery of discoloration on some pages of the Atlantic Codex (AC) of Leonardo da Vinci kept in the Biblioteca Ambrosiana in Milan, some investigations have been carried out to verify the presence of microorganisms, such as bacteria and fungi. To verify the presence of microorganisms a noninvasive method of sampling has been used that was efficient and allowed us to highlight the microbial facies of the material that was examined using conventional microbiological techniques. The microclimatic conditions in the storage room as well as the water content of the volume were also assessed. The combined observations allowed the conclusion that the discoloration of suspected biological origin on some pages of AC is not related to the presence or current attack of microbial agents. PMID:25574171

  11. Identification of a 34 kDa protein specific to synaptic vesicles

    PubMed Central

    Miller, Kenneth G.; Wendland, Beverly; Scheller, Richard H.

    2016-01-01

    In this study, we used synaptic vesicles purified from the electric organ of marine electric rays to search for novel molecules which have important functions in synaptic transmission. Proteins that copurified with synaptic vesicles were used to immunize rats, and the resulting antisera were then used to further characterize the vesicle proteins. One of the antisera recognizes a protein of 34 kDa, p34, that has several characteristics which suggest it is a synaptic vesicle specific protein: (1) it copurifies exclusively with the synaptic vesicle peak during permeation chromatography on a controlled pore glass beads column, (2) it can be immunoprecipitated with intact synaptic vesicles and (3) it is specifically localized to the nervous system. The results suggest that p34 is a synaptic vesicle specific protein with a widespread distribution in the nervous system. PMID:8358632

  12. The binary Feige 24 - The mass, radius, and gravitational redshift of the DA white dwarf

    NASA Technical Reports Server (NTRS)

    Vennes, Stephane; Shipman, Harry L.; Thorstensen, John R.; Thejll, Peter

    1991-01-01

    Observations are reported which refine the binary ephemeris of the Feige 24 system, which contains a peculiar hot DA white dwarf and an M dwarf with an atmosphere illuminated by extreme ultraviolet radiation from the white dwarf. With the new ephemeris and a set of IUE high-dispersion spectra, showing phase-dependent redshifted C IV, N V, and Si IV resonance lines, the orbital velocity, and hence the mass (0.54 + or - 0.20 solar masses), and the gravitational redshift of the white dwarf (14.1 + or - 5.2 km/s) are determined independently. It is shown that the measured Einstein redshift is consistent with an estimated radius for the white dwarf obtained from a model atmosphere solid angle and a parallax measurement. This radius is twice the Hamada-Salpeter radius for the given mass and offers a prospect to investigate the presence of a massive hydrogen envelope in that white dwarf star.

  13. Da Vinci Fluids, catch-up dynamics and dense granular flow

    E-print Network

    Raphael Blumenfeld; Sam F. Edwards; Moshe Schwartz

    2010-04-22

    We introduce and study a da Vinci Fluid, a fluid whose dissipation is dominated by solid friction. We analyse the flow rheology of a discrete model and then coarse-grain it to the continuum. We find that the model gives rise to behaviour that is characteristic of dense granular fluids. In particular, it leads to plug flow. We analyse the nucleation mechanism of plugs and their development. We find that plug boundaries generically expand and we calculate the growth rate of plug regions. In systems whose internal effective friction coefficient is relatively uniform we find that the linear size of plug regions grows as (time)$^{1/3}$. The suitability of the model to granular materials is discussed.

  14. Enhancement of uranium 234 in springwaters of Águas da Prata, São Paulo, Brazil

    NASA Astrophysics Data System (ADS)

    Bonotto, Daniel Marcos

    1993-07-01

    Springwater samples were collected at Águas da Prata, an important spa in S?o Paulo State, Brazil. The 238U and 234U isotopes were evaluated for Platina, Paiol, Villela, Prata-Radioativa, Prata-Nova, Boi, Vitória, and Prata-Antiga springs. An inverse logarithmic correlation was found between 234U/238U activity ratio and 222Rn content of the studied waters, which was related to different solution mechanisms of 222Rn and 234U nuclides at the rock-water interface. A linear correlation also exists between the 234U/238U activity ratios of the studied waters and total dissolved solids, ionic strength, CO2 partial pressure, and index of base exchange, which indicates that the enhancement of 234U in solution increases with the degree of weathering in the aquifers. A higher 234U/238U activity ratio was found to be directly related to a higher value of dissolution rate.

  15. Theoretical profiles of Lyman-alpha satellites and application to synthetic spectra of DA white dwarfs

    NASA Technical Reports Server (NTRS)

    Allard, N. F.; Koester, D.

    1992-01-01

    We present new theoretical calculations for the red wing of the Lyman-alpha profile. Close collisions with neutral and ionized hydrogen lead to the formation of the pseudomolecules H-H and H-H(+) with the appearance of satellite features near 1600 and 1400 A. The calculations include multiperturber effects, which are responsible for the formation of H3 and H3 with features near 1950 and 2600 A. The theoretical absorption profiles are included in stellar atmosphere codes and used to predict synthetic spectra for DA white dwarfs of intermediate temperatures (20,000 to 8000 K). These new calculations offer a unique opportunity to determine accurate effective temperatures and surface gravities for the variable ZZ Ceti stars.

  16. AiiDA: Automated Interactive Infrastructure and Database for Computational Science

    E-print Network

    Pizzi, Giovanni; Sabatini, Riccardo; Marzari, Nicola; Kozinsky, Boris

    2015-01-01

    Computational science has seen in the last decades a spectacular rise in the scope, breadth, and depth of its efforts. Notwithstanding this prevalence and impact, it is often still performed using the renaissance model of individual artisans gathered in a workshop, under the guidance of an established practitioner. Great benefits could follow instead from adopting concepts and tools coming from computer science to manage, preserve, and share these computational efforts. We illustrate here our paradigm sustaining such vision, based around the four pillars of Automation, Data, Environment, and Sharing, and discuss its implementation in the open-source AiiDA platform (http://www.aiida.net). The platform is tuned first to the demands of computational materials science: coupling remote management with automatic data generation; ensuring provenance, preservation, and searchability of heterogeneous data through a design based on directed acyclic graphs; encoding complex sequences of low-level codes into scientific w...

  17. Integrating Leonardo da Vinci's principles of demonstration, uncertainty, and cultivation in contemporary nursing education.

    PubMed

    Story, Lachel; Butts, Janie

    2014-03-01

    Nurses today are facing an ever changing health care system. Stimulated by health care reform and limited resources, nursing education is being challenged to prepare nurses for this uncertain environment. Looking to the past can offer possible solutions to the issues nursing education is confronting. Seven principles of da Vincian thinking have been identified (Gelb, 2004). As a follow-up to an exploration of the curiosità principle (Butts & Story, 2013), this article will explore the three principles of dimostrazione, sfumato, and corporalita. Nursing faculty can set the stage for a meaningful educational experience through these principles of demonstration (dimostrazione), uncertainty (sfumato), and cultivation (corporalita). Preparing nurses not only to manage but also to flourish in the current health care environment that will enhance the nurse's and patient's experience. PMID:23830068

  18. Test of ''Crab-Waist'' Collisions at the DA{Phi}NE {Phi} Factory

    SciTech Connect

    Zobov, M.; Alesini, D.; Biagini, M. E.; Biscari, C.; Bocci, A.; Boni, R.; Boscolo, M.; Bossi, F.; Buonomo, B.; Clozza, A.; Delle Monache, G. O.; Demma, T.; Di Pasquale, E.; Di Pirro, G.; Drago, A.; Gallo, A.; Ghigo, A.; Guiducci, S.; Ligi, C.; Marcellini, F.

    2010-04-30

    The electron-positron collider DA{Phi}NE, the Italian {Phi} factory, has been recently upgraded in order to implement an innovative collision scheme based on large crossing angle, small beam sizes at the crossing point, and compensation of beam-beam interaction by means of sextupole pairs creating a ''crab-waist'' configuration in the interaction region. Experimental tests of the novel scheme exhibited an increase by a factor of 3 in the peak luminosity of the collider with respect to the performances reached before the upgrade. In this Letter we present the new collision scheme, discuss its advantages, describe the hardware modifications realized for the upgrade, and report the results of the experimental tests carried out during commissioning of the machine in the new configuration and standard operation for the users.

  19. THE KEPLER LIGHT CURVE OF THE UNIQUE DA WHITE DWARF BOKS 53856

    SciTech Connect

    Holberg, J. B.; Howell, Steve B. E-mail: howell@noao.edu

    2011-08-15

    The faint (g = 16.9) hot white dwarf BOKS 53856 was observed by the Kepler Mission in short cadence mode during mid-2009. Analysis of these observations reveals a highly stable modulation with a period of 6.1375 hr and a 2.46% half-amplitude. The folded light curve has an unusual shape that is difficult to explain in terms of a binary system containing an unseen companion more luminous than an L0 brown dwarf. Optical spectra of BOKS 53856 show a T{sub eff} = 34,000 K, log g = 8.0 DA white dwarf. There are few, if any, known white dwarfs in this temperature range exhibiting photometric variations similar to those we describe. A magnetic spin-modulated white dwarf model can in principle explain the light curve, an interpretation supported by spectral observations of the H{alpha} line showing evidence of Zeeman splitting.

  20. First experimental evidence for heavy hyperhydrogen 6?H by the FINUDA experiment at DA?NE

    NASA Astrophysics Data System (ADS)

    Feliciello, Alessandro

    2014-12-01

    The FINUDA experiment, carried out at the Frascati phi-factory DA?NE, allowed to find the first experimental evidence for the existence of the neutron-rich hypernucleus 6?H by measuring in coincidence (?+,?-) pairs from the K-stop + 6Li ? 6?H + ?+ production reaction, followed by the 6?H ? 6He + ?- mesonic weak decay. The production rate of 6?H undergoing such a two-body ?- decay turned out to be (2.9 ± 2.0) × 10-6/K-stop. A binding energy value B?(6?H) = (4.0 ± 1.1) MeV was evaluated with respect to the (5H + ?) threshold by combining the information from both production and decay processes. A systematic difference of (0.98 ± 0.74) MeV observed between B? values when derived separately from 6?H formation and from its decay was tentatively assigned to the 6?H 0+g.s. ? 1+ excitation.

  1. [Dr Guillermo Contreras Da Silva, a relevant figure in the development of Chilean microbiology].

    PubMed

    Cabello, Felipe C

    2008-02-01

    The influence of the work of Dr. Guillermo Contreras Da Silva and his colaborators on the evolution of microbiology in Chile is briefly analyzed. Dr. Contreras was trained in modern virology at Yale University with Dr. J. Melnick under the sponsorhip of the Rockefeller Foundation. During this training, he used serological methods to classify Cocksakie viruses. After his return to Chile, he studied the epidemiology of enteroviruses, including poliovirus. His laboratory, the country's first in modern virology, took an active role in Chile's first Sabin polio vaccination in 1961. Dr. Contreras and his group transformed the teaching and the character of microbiology in Chile from a descriptive medically oriented discipline into an autonomous, quantitative and experimental science. They modernized microbiology with the introduction of molecular biology and microbial genetics and fostered collaborations with allied biological sciences. Dr. Contreras was a Guggenheim Fellow, and until his retirement, was the Chief of the Viral Products Division, Bureau of Biologies, Ottawa, Canada. PMID:18483682

  2. Middle Paleolithic human remains from the Gruta Da Oliveira (Torres Novas), Portugal.

    PubMed

    Willman, John C; Maki, Julia; Bayle, Priscilla; Trinkaus, Erik; Zilhão, João

    2012-09-01

    Additional Middle Paleolithic human remains from layers 17, 18, and 22 of the Gruta da Oliveira, Portugal consist of a proximal manual phalanx 2 (Oliveira 5), a partial postcanine tooth (Oliveira 6), a humeral diaphysis (Oliveira 7), a distal mandibular molar (Oliveira 8), and a mandibular premolar (P(3) ) (Oliveira 9). Oliveira 5, 6, and 8 are unremarkable for Late Pleistocene humans. The Oliveira 7 right humerus is moderately robust or the individual had the stocky body proportions of other European (including Iberian) Neandertals. The Oliveira 9 P(3) has a large and symmetrical crown and lacks a distal accessory ridge and accessory lingual cusps, overlapping both Neandertal and recent human ranges of variation. It contrasts with at least recent human P(3) s in having relatively thin enamel. These join the Oliveira 1 to 4 remains in further documenting early MIS 3 Neandertal morphology in western Iberia. PMID:22610966

  3. Refurbishment, reloading of the Da Lat Nuclear Research Reactor and renovation of its control system

    SciTech Connect

    Tran Ha Anh; Tran Khacan; Trinh Dinh Hal

    1994-12-31

    As the main scientific tool at the Nuclear Research Institute (NRI), the Da Lat Nuclear Research Reactor is playing a special role in the development of nuclear application in Viet Nam. Reconstructed from the previous TRIGAMARK II, it has been operating since, 1984, totalling 13,500 hrs. Since November 1992 it has undergone a general inspection followed by a complete refurbishment in response to technical requirement for ensuring its reliability and safety. The reactor, shut down for main inspection and refurbishment tasks until March 1993, was put into operation alternately with the remaining refurbishment works. In pullet the renovation of its control and instrumentation system has been carried out. This has been thought necessary due to spare part procurement problems and the need to modernize the system for improving its reliability. Finally, a programme for reloading the reactor core is being implemented, in order to increase its reserve reactivity.

  4. Radiative Levitation of Silicon in the Atmospheres of Two Hyades DA White Dwarfs

    E-print Network

    Chayer, P

    2013-01-01

    The presence of silicon at the surface of the two Hyades DA white dwarfs WD 0421+162 and WD 0431+126 requires mechanisms that counteract the effects of the downward diffusion. Radiative levitation calculations indicate that the silicon abundance observed in WD 0431+126 corresponds to the abundance supported by radiative levitation. Detailed time-dependent diffusion calculations that take into account radiative levitation and accretion indicate that accretion with rates of dM/dt(Si) levitation. In the case of WD 0421+162, accretion with a rate of dM/dt(Si) = 1.25E5 g/s must be invoked, because its observed silicon abundance is larger than the abundance supported by radiative levitation. This accretion rate is lower than the accretion rate given by the accretion-diffusion model, because the radiative levitation slows down the downward diffusion of silicon. The silicon abundances observed in the two Hyades white dwarfs ...

  5. The synthesis and spectral properties of a stimuli-responsive D-?-A charge transfer dye

    NASA Astrophysics Data System (ADS)

    Kim, Sung-Hoon; Gwon, Seon-Yeong; Bae, Jin-Seok; Son, Young-A.

    2011-01-01

    A new donor-?-acceptor (D-?-A) type isophorone dye was synthesized by the condensation reaction between 2-(3,5,5-trimethylcyclohex-2-enylidene)-malononitrile and indole-3-carboxaldehyde. The chemical structure of the dye was characterized by 1H NMR, EA and MS. A novel, chromogenic, fluorescent dye based on indol as donor unit and isophorone as acceptor unit displayed marked UV-visible absorption changes and highly selective fluorescence quenching in the presence of fluoride ion. The dye also exhibited sizeable colour changes when used as a pH-induced molecular switch and as a detector for volatile organic compounds. The absorption and fluorescent intensity of the dye can be reversibly selected by protonation/deprotonation of the amine moiety via control of intramolecular charge transfer (ICT), leading to a molecular switch with "on" and "off" states.

  6. Lista de Problemas da Area II 1. Modelo de Blume-Capel I (Salinas): Considere um modelo unidimensional

    E-print Network

    Stariolo, Daniel Adrián

    N 2 , u( , )f( )f( ) e S NkB = - f() ln f() respectivamente. Minimizando a energia livre U - TS . 6. Ponto tricrítico (Pathria): Considere um sistema descrito por uma energia livre de Landau da transferência. (b) Calcule expressões para a energia interna e a entropia por spin. (c) Qual o estado

  7. Crystal Structure of a 16 kDa Double-headed Bowman-Birk Trypsin Inhibitor from Barley Seeds at

    E-print Network

    Suh, Se Won

    Crystal Structure of a 16 kDa Double-headed Bowman- Birk Trypsin Inhibitor from Barley Seeds at 1 The Bowman-Birk trypsin inhibitor from barley seeds (BBBI) consists of 125 amino acid residues with two trypsin inhibitor; BBBI, barley Bowman-Birk trypsin inhibitor; BBI, Bowman-Birk protease inhibitor; BPT

  8. Representation and Control of Infinite Dimensional Systems, by A. Bensoussan, G. Da Prato, M. C. Delfour, S. K. Mitter

    E-print Network

    Rathinam, Muruhan

    Representation and Control of Infinite Dimensional Systems, 2nd edition by A. Bensoussan, G. Da with the behavior of dynamical systems. If we look back to the 1 #12;inception of control theory as a subject the treatment of the first 1992- 1993 two-volume edition [2] was in using the modern functional analytically

  9. Bringing the ZPD into the Equation: Capturing L2 Development during Computerized Dynamic Assessment (C-DA)

    ERIC Educational Resources Information Center

    Poehner, Matthew E.; Lantolf, James P.

    2013-01-01

    Dynamic Assessment (DA) derives from Vygotsky's (1987) insight that the use of mediation, attuned to learner needs, enables learners to perform beyond their current level of functioning, thereby providing insights into emerging capabilities. The instructional quality of mediation means that this process simultaneously creates possibilities…

  10. Activation, Inhibition, and Regiospecificity of the Lysophospholipase Activity of the 85-kDa Group IV Cytosolic

    E-print Network

    Dennis, Edward A.

    Activation, Inhibition, and Regiospecificity of the Lysophospholipase Activity of the 85-kDa Group is accelerated in the presence of glyc- erol. We now find that this apparent increase in activity is accounted, as is the case for this enzyme's phospholipase A2 (PLA2) activity. In contrast, dioleoylglycerol, which

  11. Simultaneous voltammetric determination for DA, AA and NO2(-) based on graphene/poly-cyclodextrin/MWCNTs nanocomposite platform.

    PubMed

    Zhang, Yu; Yuan, Ruo; Chai, Yaqin; Li, Wenjuan; Zhong, Xia; Zhong, Huaan

    2011-05-15

    In the present work, graphene sheets (GS) and multiwall carbon nanotubes (MWCNTs) were dispersed in the mixed solution of cyclodextrin (CD) and cyclodextrin prepolymer (pre-CD) and were used as modifier to fabricate chemical modified electrode to simultaneous detect dopamine (DA), ascorbic acid (AA) and nitrite (NO2(-)). CD cross-linked pre-CD (CDP) displays excellent film forming ability, which made the electrode stable. Comparing with CDP-GS, CDP-MWCNTs and CDP-GS-MWCNTs modified electrodes, the CDP-GS-MWCNTs displays higher catalytic activity and selectivity toward the oxidation of DA, AA and NO2(-), revealing that MWCNTs effectively inhibited the stacking of individual GS and enhanced the utilization of GS based composites. The host-guest chemical reaction ability of CD and ?-? stacking interaction between detected molecules and GS-MWCNTs surface were considered as the main reasons of the successfully simultaneous detection of DA, AA and NO2(-). Cyclic voltammetry (CV), scanning electron microscopy (SEM) and different pulse voltammetry (DPV) were employed to characterize the biosensor. The linear response range for AA, DA and NO2(-) were 5?M-0.48mM, 0.15-21.65?M and 5?M-6.75mM, respectively and the detection limits were 1.65?M, 0.05?M and 1.65?M. PMID:21497078

  12. An error in "On a new formal proof model for RFID location Da-Zhi Sun a, *

    E-print Network

    International Association for Cryptologic Research (IACR)

    Frequency Identification (RFID) systems are a promising automatic identification technology. Basically, RFIDAn error in "On a new formal proof model for RFID location privacy" Da-Zhi Sun a, * a School evaluated five formal RFID privacy models. One main result is that Ha et al.'s RFID privacy model

  13. MR-Guided Interventions for Prostate Cancer Ergin Atalar, PhDa,b,*, Cynthia Me nard, MDc

    E-print Network

    Atalar, Ergin

    MR-Guided Interventions for Prostate Cancer Ergin Atalar, PhDa,b,*, Cynthia Me´ nard, MDc,000 cases in 2004, prostate cancer is the most common noncutaneous cancer in men in the United States [1 of prostate cancer care, including diagnosis, prognostication, and treatment. First and foremost is a pressing

  14. THE REMARKABLE X-RAY JET IN THE QUASAR 4C 20.24 D.A. Schwartz1

    E-print Network

    Gelbord, Jonathan

    , Australia 7 Jet Propulsion Laboratory, 4800 Oak Grove Drive, Pasadena, CA 91109, USA 8 Fermi National1 THE REMARKABLE X-RAY JET IN THE QUASAR 4C 20.24 D.A. Schwartz1 , H.L. Marshall2 , J. Gelbord2 , E Accelerator Laboratory, P.O. Box 500, Batavia, IL, 60510, USA ABSTRACT The Chandra X-ray telescope has

  15. Educating in the Design and Construction of Built Environments Accessible to Disabled People: The Leonardo da Vinci AWARD Project

    ERIC Educational Resources Information Center

    Frattari, Antonio; Dalpra, Michela; Bernardi, Fabio

    2013-01-01

    An interdisciplinary partnership within an European Leonardo da Vinci project has developed a new approach aimed at educating secondary school students in the creation of built environments accessible to disabled people and at sensitizing them towards the inclusion of people with disabilities in all realms of social life. The AWARD (Accessible…

  16. Virtual Mobility in Reality: A Study of the Use of ICT in Finnish Leonardo da Vinci Mobility Projects.

    ERIC Educational Resources Information Center

    Valjus, Sonja

    An e-mail survey and interviews collected data on use of information and communications technology (ICT) in Finnish Leonardo da Vinci mobility projects from 2000-02. Findings showed that the most common ICT tools used were e-mail, digital tools, and the World Wide Web; ICT was used during all project phases; the most common problems concerned…

  17. MENTORED RESEARCH FUNDING OPPORTUNITY FOR MEDICAL STUDENTS UC DA TSC)VIS Clinical and Translational Science Center (C

    E-print Network

    Leistikow, Bruce N.

    MENTORED RESEARCH FUNDING OPPORTUNITY FOR MEDICAL STUDENTS UC DA TSC)VIS Clinical and Translational research relevant to human health. In line with the NIH focus on translational research to bridge the gap in multidisciplinary, translational biomedical research 6. Identification of a faculty mentor and strong mentor support

  18. Multi-objective Design Space Exploration based on UML Marcio F. da S. Oliveira, Eduardo W. Brio, Francisco A. Nascimento,

    E-print Network

    Wagner, Flávio Rech

    Multi-objective Design Space Exploration based on UML Marcio F. da S. Oliveira, Eduardo W. Brião, flavio}@inf.ufrgs.br Abstract. This paper proposes a Design Space Exploration (DSE) framework using UML requiring costly hardware synthesis and code generation steps. A design space exploration scenario

  19. ESTRUTURAO GENTICA DAS POPULAES DE DUAS ESPCIES DE PEIXES RECIFAIS DO ATOL DAS ROCAS E DA COSTA DO CEAR.

    E-print Network

    Solé-Cava, Antonio M.

    193 ESTRUTURAÇÃO GENÉTICA DAS POPULAÇÕES DE DUAS ESPÉCIES DE PEIXES RECIFAIS DO ATOL DAS ROCAS E DA UFRJ Recebido: 16/03/2003 Aceito: 10/10/2003 RESUMO O Atol das Rocas, que recentemente foi declarado genética dessas populações. Foram analisadas geneticamente populações do Atol das Rocas e Costa do Ceará

  20. Notes for first lectures Statistics 215 DA Freedman Text. Freedman, Statistical Models: Theory and Practice, Cambridge (2005).

    E-print Network

    Freedman, David A.

    2005-01-01

    Notes for first lectures Statistics 215 DA Freedman Text. Freedman, Statistical Models: Theory-Bartsch Read. Talk. Work exercises. No Midterm. No Homework. Pop quizzes? Labs. Project. Final. Final exam" the controls to the cases, which we're ignoring here.) STUDIES VS ANECDOTES: THE CONTROL GROUP 3 #12;Cohort