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Sample records for effective warning labels

  1. An experiment in designing effective warning labels.

    PubMed

    Gorn, G J; Lavack, A M; Pollack, C R; Weinberg, C B

    1996-01-01

    This paper proposes a model for the design of effective warning labels concerning drinking and driving. One important aspect of the model is that producing a multiplicity of warning labels should result in a higher probability that at least a few of the warning labels will be of high quality and effectiveness. Secondly, greater similarity between the warning label designer and the intended target group should enhance the effectiveness of the warning label. In the present study, 49 warning labels were created by university undergraduates, and the effectiveness of these warning labels was assessed by a group of university students (target group members). A number of labels were judged as being effective, and more effective than the government warning label. Extending the notion of being close to the target group, warning labels designed by male and female university students for university students of the same sex were judged as more effective than warning labels designed for the opposite sex. PMID:10164447

  2. Enhancing the effectiveness of tobacco package warning labels: a social psychological perspective

    PubMed Central

    Strahan, E; White, K; Fong, G; Fabrigar, L; Zanna, M; Cameron, R

    2002-01-01

    Objective: To outline social psychological principles that could influence the psychosocial and behavioural effects of tobacco warning labels, and to inform the development of more effective tobacco warning labels. Data sources: PsycInfo and Medline literature searches and expert guided selection of principles and theories in social psychology and of tobacco warning labels, including articles, books, and reports. Conclusions: Tobacco warning labels represent a potentially effective method of influencing attitudes and behaviours. This review describes social psychological principles that could be used to guide the creation of more effective warning labels. The potential value of incorporating warning labels into a broader public health education campaign is discussed, and directions for future research are suggested. PMID:12198266

  3. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...following information: DANGER BERYLLIUM CAN CAUSE LUNG DAMAGE CANCER HAZARD AUTHORIZED PERSONNEL ONLY (b) Warning labels...DO NOT REMOVE DUST BY BLOWING OR SHAKING CANCER AND LUNG DISEASE HAZARD (c) Warning signs and labels...

  4. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...following information: DANGER BERYLLIUM CAN CAUSE LUNG DAMAGE CANCER HAZARD AUTHORIZED PERSONNEL ONLY (b) Warning labels...DO NOT REMOVE DUST BY BLOWING OR SHAKING CANCER AND LUNG DISEASE HAZARD (c) Warning signs and labels...

  5. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...following information: DANGER BERYLLIUM CAN CAUSE LUNG DAMAGE CANCER HAZARD AUTHORIZED PERSONNEL ONLY (b) Warning labels...DO NOT REMOVE DUST BY BLOWING OR SHAKING CANCER AND LUNG DISEASE HAZARD (c) Warning signs and labels...

  6. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...following information: DANGER BERYLLIUM CAN CAUSE LUNG DAMAGE CANCER HAZARD AUTHORIZED PERSONNEL ONLY (b) Warning labels...DO NOT REMOVE DUST BY BLOWING OR SHAKING CANCER AND LUNG DISEASE HAZARD (c) Warning signs and labels...

  7. Warning labels formulated as questions positively influence smoking-related risk perception.

    PubMed

    Glock, Sabine; Müller, Barbara C N; Ritter, Simone M

    2013-02-01

    Research on warning labels printed on cigarette packages has shown that fear inducing health warnings might provoke defensive responses. This study investigated whether reformulating statements into questions could avoid defensive reactions. Smokers were presented with either warning labels formulated as questions, textual warning labels, graphic warning labels, or no warning labels. Participants' smoking-related risk perception was higher after exposure to warning labels formulated as questions or no warning labels than after exposure to textual or graphic warning labels. These results indicate that reformulating statements into questions can avoid defensive responses elicited by textual- and graphic warning labels. PMID:22419415

  8. 29 CFR 1915.16 - Warning signs and labels.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT Confined and Enclosed Spaces and Other Dangerous Atmospheres in Shipyard Employment § 1915.16 Warning signs and labels. (a) Employee comprehension of signs and...

  9. 29 CFR 1915.16 - Warning signs and labels.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT Confined and Enclosed Spaces and Other Dangerous Atmospheres in Shipyard Employment § 1915.16 Warning signs and labels. (a) Employee comprehension of signs and...

  10. 29 CFR 1915.16 - Warning signs and labels.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT Confined and Enclosed Spaces and Other Dangerous Atmospheres in Shipyard Employment § 1915.16 Warning signs and labels. (a) Employee comprehension of signs and...

  11. 29 CFR 1915.16 - Warning signs and labels.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT Confined and Enclosed Spaces and Other Dangerous Atmospheres in Shipyard Employment § 1915.16 Warning signs and labels. (a) Employee comprehension of signs and...

  12. 29 CFR 1915.16 - Warning signs and labels.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT Confined and Enclosed Spaces and Other Dangerous Atmospheres in Shipyard Employment § 1915.16 Warning signs and labels. (a) Employee comprehension of signs and...

  13. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82. ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Animal food labeling warning statements. 501.17... (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ANIMAL FOOD LABELING General Provisions § 501.17...

  14. Interpretations of cigarette advertisement warning labels by Philadelphia Puerto Ricans.

    PubMed

    Morris, Nancy; Gilpin, Dawn R; Lenos, Melissa; Hobbs, Renee

    2011-09-01

    This study examined Philadelphia Puerto Ricans' interpretations of the Surgeon General's warnings that appear on cigarette packaging and in advertisements. In-home family focus groups in which participants were asked to comment on magazine cigarette advertisements showed a great variety of interpretations of the legally mandated warning labels. These findings (a) corroborate and add to research in public health and communications regarding the possibility of wide variations in message interpretations and (b) support the call for public health messages to be carefully tested for effectiveness among different social groups. The article's focus on Puerto Ricans addresses the problem of misleading conclusions that can arise from aggregating all Latino subpopulations into one group. The use of a naturalistic setting to examine interpretations of messages about smoking departs from the experimental methods typically used for such research and provides new evidence that even a seemingly straightforward message can be interpreted in multiple ways. Understanding and addressing differences in message interpretation can guide public health campaigns aimed at reducing health disparities. PMID:21534024

  15. The evolution of health warning labels on cigarette packs: the role of precedents, and tobacco industry strategies to block diffusion

    PubMed Central

    Hiilamo, Heikki; Crosbie, Eric; Glantz, Stanton A

    2013-01-01

    Objective To analyse the evolution and diffusion of health warnings on cigarette packs around the world, including tobacco industry attempts to block this diffusion. Methods We analysed tobacco industry documents and public sources to construct a database on the global evolution and diffusion of health warning labels from 1966 to 2012, and also analysed industry strategies. Results Health warning labels, especially labels with graphic elements, threaten the tobacco industry because they are a low-cost, effective measure to reduce smoking. Multinational tobacco companies did not object to voluntary innocuous warnings with ambiguous health messages, in part because they saw them as offering protection from lawsuits and local packaging regulations. The companies worked systematically at the international level to block or weaken warnings once stronger more specific warnings began to appear in the 1970s. Since 1985 in Iceland, the tobacco industry has been aware of the effectiveness of graphic health warning labels (GWHL). The industry launched an all-out attack in the early 1990s to prevent GHWLs, and was successful in delaying GHWLs internationally for nearly 10 years. Conclusions Beginning in 2005, as a result of the World Health Organisation Framework Convention on Tobacco Control (FCTC), GHWLs began to spread. Effective implementation of FCTC labelling provisions has stimulated diffusion of strong health warning labels despite industry opposition. PMID:23092884

  16. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82. ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Animal food labeling warning statements. 501.17 Section 501.17 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  17. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82. ... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Animal food labeling warning statements. 501.17 Section 501.17 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  18. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82. ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Animal food labeling warning statements. 501.17 Section 501.17 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  19. Effects of exposure to thin-ideal media images on body dissatisfaction: testing the inclusion of a disclaimer versus warning label.

    PubMed

    Ata, Rheanna N; Thompson, J Kevin; Small, Brent J

    2013-09-01

    The current study was designed to determine whether the inclusion of a disclaimer (i.e., "Retouched photograph aimed at changing a person's physical appearance.") or warning (i.e., "Warning: Trying to look as thin as this model may be dangerous to your health.") added to images of thin/attractive models would affect body dissatisfaction and intent to diet in female undergraduate students (n=342). Participants were randomly assigned to one of four groups: (a) disclaimer, (b) warning, (c) model control, or (d) car control. Results revealed a significant interaction between group and time, whereby only the car control group reported a significant change (i.e., decrease) in body dissatisfaction over time. Groups did not differ on intent to diet measured at post-exposure. The results largely replicate other findings in this area and call into question advocacy efforts to label media images as a strategy to decrease women's identification with the stimuli. PMID:23688859

  20. Perceptions of prescription warning labels within an underserved population

    PubMed Central

    Shiyanbola, Olayinka O.; Meyer, Brittney A.; Locke, Michelle R.; Wettergreen, Sara

    Objective To understand how underserved populations attend to prescription warning label (PWL) instructions, examine the importance of PWL instructions to participants and describe the challenges associated with interpreting the information on PWLs. Methods Adults from an underserved population (racial and ethnic minorities, individuals with low income, older adults) who had a history of prescription medication use and were able to understand English took part in semi-structured interviews. Participants were presented with eight different prescription bottles with an attached PWL. Participants were asked, “If this prescription was yours, what information would you need to know about the medicine?” The number of participants who attended to the warning labels was noted. Other questions assessed the importance of PWLs, the challenges with understanding PWLs, and ways a pharmacist could help participant understanding of the PWL. Results There were 103 participants. The mean age was 50.25 years (SD=18.05). Majority attended to the PWL. Participants not currently taking medications and who had limited health literacy were likely to overlook the warning labels. Majority rated the warning instructions to be extremely important (n=86, 83.5 %), wanted the pharmacist to help them understand PWLs by counseling them on the information on the label (n=63, 61.2%), and thought the graphics made the label information easy to understand. Conclusions PWLs are an important method of communicating medication information, as long as they are easily comprehensible to patients. In addition to placing PWLs on prescription bottles, health care providers need to counsel underserved populations on medication warnings, especially individuals with limited health literacy who are not currently using a prescription medication. PMID:24644523

  1. Graphic Warning Labels Elicit Affective and Thoughtful Responses from Smokers: Results of a Randomized Clinical Trial

    PubMed Central

    Evans, Abigail T.; Peters, Ellen; Strasser, Andrew A.; Emery, Lydia F.; Sheerin, Kaitlin M.; Romer, Daniel

    2015-01-01

    Objective Observational research suggests that placing graphic images on cigarette warning labels can reduce smoking rates, but field studies lack experimental control. Our primary objective was to determine the psychological processes set in motion by naturalistic exposure to graphic vs. text-only warnings in a randomized clinical trial involving exposure to modified cigarette packs over a 4-week period. Theories of graphic-warning impact were tested by examining affect toward smoking, credibility of warning information, risk perceptions, quit intentions, warning label memory, and smoking risk knowledge. Methods Adults who smoked between 5 and 40 cigarettes daily (N = 293; mean age = 33.7), did not have a contra-indicated medical condition, and did not intend to quit were recruited from Philadelphia, PA and Columbus, OH. Smokers were randomly assigned to receive their own brand of cigarettes for four weeks in one of three warning conditions: text only, graphic images plus text, or graphic images with elaborated text. Results Data from 244 participants who completed the trial were analyzed in structural-equation models. The presence of graphic images (compared to text-only) caused more negative affect toward smoking, a process that indirectly influenced risk perceptions and quit intentions (e.g., image->negative affect->risk perception->quit intention). Negative affect from graphic images also enhanced warning credibility including through increased scrutiny of the warnings, a process that also indirectly affected risk perceptions and quit intentions (e.g., image->negative affect->risk scrutiny->warning credibility->risk perception->quit intention). Unexpectedly, elaborated text reduced warning credibility. Finally, graphic warnings increased warning-information recall and indirectly increased smoking-risk knowledge at the end of the trial and one month later. Conclusions In the first naturalistic clinical trial conducted, graphic warning labels are more effective than text-only warnings in encouraging smokers to consider quitting and in educating them about smoking’s risks. Negative affective reactions to smoking, thinking about risks, and perceptions of credibility are mediators of their impact. Trial Registration Clinicaltrials.gov NCT01782053 PMID:26672982

  2. Appalachian Residents’ Perspectives on New U.S. Cigarette Warning Labels

    PubMed Central

    Reiter, Paul L.; Broder-Oldach, Benjamin; Ellen Wewers, Mary; Klein, Elizabeth G.; Paskett, Electra D.; Katz, Mira L.

    2012-01-01

    Introduction The U.S. Food and Drug Administration revealed new pictorial warning labels in June 2011 for cigarette packages, yet little is known about how these labels are perceived by U.S. residents. We examined the reactions to and attitudes about the new labels among residents of Appalachian Ohio, a region with a high smoking prevalence. Methods We conducted focus groups with Appalachian Ohio residents between July and October 2011. Participants included healthcare providers (n=30), community leaders (n=26), parents (n=28), and young adult men ages 18–26 (n=18). Results Most participants supported the addition of the new labels to U.S. cigarette packages, though many were unaware of the labels prior to the focus groups. Participants did not think the labels would be effective in promoting smoking cessation among smokers in their communities, but they were more positive about the potential of the labels to reduce smoking initiation. Smokers reported positive feedback about the more graphic labels, particularly those showing a man with a tracheal stoma or a person with severe oral disease. The labels that include a cartoon image of an ill infant and a man who quit smoking received the most negative feedback. Conclusions Participants generally supported adding pictorial warning labels to U.S. cigarette packages, but only a few of labels received mostly positive feedback. Results offer early insight into how the new labels may be received if they are put into practice. PMID:22527659

  3. FDA cigarette warning labels lower craving and elicit frontoinsular activation in adolescent smokers.

    PubMed

    Do, Kathy T; Galván, Adriana

    2015-11-01

    Cigarette smoking is an economically and epidemiologically expensive public health concern. Most adult smokers become addicted during adolescence, rendering it a crucial period for prevention and intervention. Although litigation claims have delayed implementation, graphic warning labels proposed by the U.S. Food and Drug Administration (FDA) may be a promising way to achieve this goal. We aimed to determine the efficacy of the labels in reducing in-scanner craving and to characterize the neurobiological responses in adolescent and adult smokers and non-smokers. While undergoing functional magnetic resonance imaging, thirty-nine 13- to 18-year-old adolescent and forty-one 25- to 30-year-old adult smokers and non-smokers rated their desire to smoke when presented with emotionally graphic warning labels and comparison non-graphic labels. Compared with adult smokers, adolescent smokers exhibited greater craving reduction in response to the warning labels. Although smokers evinced overall blunted recruitment of insula and dorsolateral prefrontal cortex (DLPFC) relative to non-smokers, an effect that was stronger in adolescent smokers, parametrically increasing activation of these regions was associated with greater craving reduction. Functional connectivity analyses suggest that greater DLPFC regulation of limbic regions predicted cigarette craving. These data underscore a prominent role of frontoinsular circuitry in predicting the efficacy of FDA graphic warning labels in craving reduction in adult and adolescent smokers. PMID:25887154

  4. Can cigarette warnings counterbalance effects of smoking scenes in movies?

    PubMed

    Golmier, Isabelle; Chebat, Jean-Charles; Gélinas-Chebat, Claire

    2007-02-01

    Scenes in movies where smoking occurs have been empirically shown to influence teenagers to smoke cigarettes. The capacity of a Canadian warning label on cigarette packages to decrease the effects of smoking scenes in popular movies has been investigated. A 2 x 3 factorial design was used to test the effects of the same movie scene with or without electronic manipulation of all elements related to smoking, and cigarette pack warnings, i.e., no warning, text-only warning, and text+picture warning. Smoking-related stereotypes and intent to smoke of teenagers were measured. It was found that, in the absence of warning, and in the presence of smoking scenes, teenagers showed positive smoking-related stereotypes. However, these effects were not observed if the teenagers were first exposed to a picture and text warning. Also, smoking-related stereotypes mediated the relationship of the combined presentation of a text and picture warning and a smoking scene on teenagers' intent to smoke. Effectiveness of Canadian warning labels to prevent or to decrease cigarette smoking among teenagers is discussed, and areas of research are proposed. PMID:17450995

  5. The Efficacy of Cigarette Warning Labels on Health Beliefs in the United States and Mexico

    PubMed Central

    MUTTI, SEEMA; HAMMOND, DAVID; REID, JESSICA L.; THRASHER, JAMES F.

    2013-01-01

    Concern over health risks is the most common motivation for quitting smoking. Health warnings on tobacco packages are among the most prominent interventions to convey the health risks of smoking. Face-to-face surveys were conducted in Mexico (n=1,072), and a web-based survey was conducted in the US (n=1,449) to examine the efficacy of health warning labels on health beliefs. Respondents were randomly assigned to view two sets of health warnings (each with one text-only warning and 5–6 pictorial warnings) for two different health effects. Respondents were asked whether they believed smoking caused 12 different health effects. Overall, the findings indicate high levels of health knowledge in both countries for some health effects, although significant knowledge gaps remained; for example: less than half of respondents agreed that smoking causes impotence and less than one third agreed that smoking causes gangrene. Mexican respondents endorsed a greater number of correct beliefs about the health impact of smoking than the US sample. In both countries, viewing related health warning labels increased beliefs about the health risks of smoking, particularly for less well-known health effects, such as gangrene, impotence, and stroke. PMID:23905611

  6. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... warning statement shall be the standard chemical name of the substance as listed in 40 CFR part 82... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Form of label bearing warning... Substances § 82.110 Form of label bearing warning statement. (a) Conspicuousness and contrast. The...

  7. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... warning statement shall be the standard chemical name of the substance as listed in 40 CFR part 82... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Form of label bearing warning... Substances § 82.110 Form of label bearing warning statement. (a) Conspicuousness and contrast. The...

  8. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (a) Conspicuousness and contrast. The warning statement shall appear in conspicuous and legible type by typography, layout, and color with other printed matter on the label. The warning statement shall appear in sharp contrast to any...

  9. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (a) Conspicuousness and contrast. The warning statement shall appear in conspicuous and legible type by typography, layout, and color with other printed matter on the label. The warning statement shall appear in sharp contrast to any...

  10. 40 CFR 82.112 - Removal of label bearing warning statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Removal of label bearing warning... Substances § 82.112 Removal of label bearing warning statement. (a) Prohibition on removal. Except as... manufacturer of a product that incorporates a product that is accompanied by a label bearing the...

  11. 40 CFR 82.112 - Removal of label bearing warning statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Removal of label bearing warning... Substances § 82.112 Removal of label bearing warning statement. (a) Prohibition on removal. Except as... manufacturer of a product that incorporates a product that is accompanied by a label bearing the...

  12. 40 CFR 82.112 - Removal of label bearing warning statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Removal of label bearing warning... Substances § 82.112 Removal of label bearing warning statement. (a) Prohibition on removal. Except as... manufacturer of a product that incorporates a product that is accompanied by a label bearing the...

  13. 40 CFR 82.112 - Removal of label bearing warning statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Removal of label bearing warning... Substances § 82.112 Removal of label bearing warning statement. (a) Prohibition on removal. Except as... manufacturer of a product that incorporates a product that is accompanied by a label bearing the...

  14. 40 CFR 82.112 - Removal of label bearing warning statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Removal of label bearing warning... Substances § 82.112 Removal of label bearing warning statement. (a) Prohibition on removal. Except as... manufacturer of a product that incorporates a product that is accompanied by a label bearing the...

  15. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... adjacent supporting structure or assembly, with the warning label shown in Fig. 7. The label shall be at... size relation to each other and to the label as shown in Fig. 7. EC03OC91.016 (b) Rotary mowers. Walk-behind rotary mowers shall have one label as shown in Fig. 7, on the blade housing. The label shall...

  16. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... adjacent supporting structure or assembly, with the warning label shown in Fig. 7. The label shall be at... size relation to each other and to the label as shown in Fig. 7. EC03OC91.016 (b) Rotary mowers. Walk-behind rotary mowers shall have one label as shown in Fig. 7, on the blade housing. The label shall...

  17. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...Warning label for reel-type and rotary power mowers. 1205.6 Section 1205.6...REGULATIONS SAFETY STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.6 Warning label for reel-type and rotary power mowers. (a) General....

  18. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...Warning label for reel-type and rotary power mowers. 1205.6 Section 1205.6...REGULATIONS SAFETY STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.6 Warning label for reel-type and rotary power mowers. (a) General....

  19. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...Warning label for reel-type and rotary power mowers. 1205.6 Section 1205.6...REGULATIONS SAFETY STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.6 Warning label for reel-type and rotary power mowers. (a) General....

  20. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...assembly, with the warning label shown in Fig. 7. The label shall be at least 3...each other and to the label as shown in Fig. 7. EC03OC91.016 (b) Rotary mowers...mowers shall have one label as shown in Fig. 7, on the blade housing. The...

  1. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...assembly, with the warning label shown in Fig. 7. The label shall be at least 3...each other and to the label as shown in Fig. 7. EC03OC91.016 (b) Rotary mowers...mowers shall have one label as shown in Fig. 7, on the blade housing. The...

  2. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...typography, layout, and color with other printed matter on the label. The warning statement shall...requirement for sharp contrast are: black letters on a dark blue or dark green background, dark red letters on a light red background,...

  3. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...typography, layout, and color with other printed matter on the label. The warning statement shall...requirement for sharp contrast are: black letters on a dark blue or dark green background, dark red letters on a light red background,...

  4. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...typography, layout, and color with other printed matter on the label. The warning statement shall...requirement for sharp contrast are: black letters on a dark blue or dark green background, dark red letters on a light red background,...

  5. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SAFETY ACT REGULATIONS SAFETY STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.6 Warning label for reel-type and rotary power mowers. (a) General. Walk-behind power lawn mowers shall be...

  6. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... SAFETY ACT REGULATIONS SAFETY STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.6 Warning label for reel-type and rotary power mowers. (a) General. Walk-behind power lawn mowers shall be...

  7. 16 CFR 1205.6 - Warning label for reel-type and rotary power mowers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... SAFETY ACT REGULATIONS SAFETY STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.6 Warning label for reel-type and rotary power mowers. (a) General. Walk-behind power lawn mowers shall be...

  8. Mediational pathways of the impact of cigarette warning labels on quit attempts

    PubMed Central

    Yong, Hua-Hie; Borland, Ron; Thrasher, James F.; Thompson, Mary E.; Nagelhout, Gera E.; Fong, Geoffrey T.; Hammond, David; Cummings, K. Michael

    2015-01-01

    Objectives To test and develop, using structural equation modelling, a robust model of the mediational pathways through which health warning labels exert their influence on smokers’ subsequent quitting behaviour. Methods Data come from the International Tobacco Control Four-Country Survey, a longitudinal cohort study conducted in Australia, Canada, the UK, and the US. Waves 5–6 data (n=4988) were used to calibrate the hypothesized model of warning label impact on subsequent quit attempts via a set of policy-specific and general psychosocial mediators. The finalised model was validated using Waves 6–7 data (n=5065). Results As hypothesized, warning label salience was positively associated with thoughts about risks of smoking stimulated by the warnings (?=.58, p<.001), which in turn were positively related to increased worry about negative outcomes of smoking (?=.52, p<.001); increased worry in turn predicted stronger intention to quit (?=.39, p<.001) which was a strong predictor of subsequent quit attempts (?=.39, p<.001). This calibrated model was successfully replicated using Waves 6–7 data. Conclusions Health warning labels seem to influence future quitting attempts primarily through their ability to stimulate thoughts about the risks of smoking, which in turn help to raise smoking-related health concerns, which lead to stronger intentions to quit, a known key predictor of future quit attempts for smokers. By making warning labels more salient and engaging, they should have a greater chance to change behaviour. PMID:24977309

  9. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program... BERYLLIUM CAN CAUSE LUNG DAMAGE CANCER HAZARD AUTHORIZED PERSONNEL ONLY...BLOWING OR SHAKING CANCER AND LUNG DISEASE HAZARD (c) Warning signs...

  10. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... food containing or manufactured with a chlorofluorocarbon or other ozone-depleting substance. Labeling requirements for animal foods that contain or are manufactured with a chlorofluorocarbon or other ozone-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82....

  11. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... signs and labels must be in accordance with 29 CFR 1910.1200, Hazard Communication. ... DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program Requirements § 850.38... access point to a regulated area with the following information: DANGER BERYLLIUM CAN CAUSE LUNG...

  12. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... signs and labels must be in accordance with 29 CFR 1910.1200, Hazard Communication. ... DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program Requirements § 850.38... access point to a regulated area with the following information: DANGER BERYLLIUM CAN CAUSE LUNG...

  13. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... signs and labels must be in accordance with 29 CFR 1910.1200, Hazard Communication. ... DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program Requirements § 850.38... access point to a regulated area with the following information: DANGER BERYLLIUM CAN CAUSE LUNG...

  14. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... signs and labels must be in accordance with 29 CFR 1910.1200, Hazard Communication. ... DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program Requirements § 850.38... access point to a regulated area with the following information: DANGER BERYLLIUM CAN CAUSE LUNG...

  15. 10 CFR 850.38 - Warning signs and labels.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... signs and labels must be in accordance with 29 CFR 1910.1200, Hazard Communication. ... DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program Requirements § 850.38... access point to a regulated area with the following information: DANGER BERYLLIUM CAN CAUSE LUNG...

  16. Cancer illustrations and warning labels on cigarette packs: perceptions of teenagers from high socioeconomic status in Lahore.

    PubMed

    Ahsen, Noor Fatima; Iqbal, Humaira

    2015-06-01

    Smoking is linked with adverse health outcomes and multi-organ diseases with six million deaths every year. The smoking population includes both genders and the habit is seen in minors as well. The cross-sectional study was conducted in Lahore among teenagers belonging to high socioeconomic class. A sample of 191 students was recruited by convenience sampling. The teenagers were questioned on their perceptions relating to prohibition labels, factors that led them to smoke, and ideas to make health warnings more effective. Overall, 66(34.55%) teenagers were smokers, and of them, 50(75.75%) were boys and 16(24.24%) were girls. Besides, 25(37.9%) smokers were of the view that smoking is a bad habit; 40(60.6%) said prohibition labels would not change the mindset of the smoker; 35(53%)believed that a smoker is completely uninfluenced by prohibition labels. Results suggest that the warning labels on cigarette packs should be made more comprehensible and alarming for smokers. PMID:26060175

  17. Disclaimer labels on fashion magazine advertisements: effects on social comparison and body dissatisfaction.

    PubMed

    Tiggemann, Marika; Slater, Amy; Bury, Belinda; Hawkins, Kimberley; Firth, Bonny

    2013-01-01

    Recent proposals across a number of Western countries have suggested that idealised media images should carry some sort of disclaimer informing readers when these images have been digitally enhanced. The present studies aimed to experimentally investigate the impact on women's body dissatisfaction of the addition of such warning labels to fashion magazine advertisements. Participants were 120 and 114 female undergraduate students in Experiment 1 and Experiment 2 respectively. In both experiments, participants viewed fashion magazine advertisements with either no warning label, a generic warning label, or a specific more detailed warning label. In neither experiment was there a significant effect of type of label. However, state appearance comparison was found to predict change in body dissatisfaction irrespective of condition. Unexpectedly, trait appearance comparison moderated the effect of label on body dissatisfaction, such that for women high on trait appearance comparison, exposure to specific warning labels actually resulted in increased body dissatisfaction. In sum, the present results showed no benefit of warning labels in ameliorating the known negative effect of viewing thin-ideal media images, and even suggested that one form of warning (specific) might be harmful for some individuals. Accordingly, it was concluded that more extensive research is required to guide the most effective use of disclaimer labels. PMID:22947622

  18. Pictorial Health Warning Label Content and Smokers' Understanding of Smoking-Related Risks--A Cross-Country Comparison

    ERIC Educational Resources Information Center

    Swayampakala, Kamala; Thrasher, James F.; Hammond, David; Yong, Hua-Hie; Bansal-Travers, Maansi; Krugman, Dean; Brown, Abraham; Borland, Ron; Hardin, James

    2015-01-01

    The aim of the present study was to assess smokers' level of agreement with smoking-related risks and toxic tobacco constituents relative to inclusion of these topics on health warning labels (HWLs). 1000 adult smokers were interviewed between 2012 and 2013 from online consumer panels of adult smokers from each of the three countries: Australia…

  19. Investigating the Effectiveness of Pictorial Health Warnings in Mauritius: Findings From the ITC Mauritius Survey

    PubMed Central

    Kaai, Susan C.; Fong, Geoffrey T.; Driezen, Pete; Quah, Anne C. K.; Burhoo, Premduth

    2014-01-01

    Introduction: Health warnings on tobacco packages are an effective strategy for informing the public about the harms associated with tobacco use. Most studies investigating the effectiveness of pictorial health warnings (PHWs) on cigarette packages are from high-income countries. This study evaluated the impact of PHWs on smokers’ perceptions and behavior in Mauritius, the first country in the World Health Organization African region to implement PHWs. Methods: Data were drawn from 3 waves of a nationally representative cohort of adult smokers from the International Tobacco Control (ITC) Mauritius Survey (n = 668). Wave 1 was conducted in 2009, 6 months prior to the implementation of PHWs. Waves 2 and 3 were conducted 10–12 months and 20–21 months, respectively, postimplementation. Six established indicators of warning effectiveness were used to evaluate the effect of PHWs on smokers’ perceptions and behavior. Results: All indicators of warning effectiveness (salience, cognitive, and behavioral reactions) and the Label Impact Index, a weighted combination of 4 indicators, increased significantly between Waves 1 and 2. However, between Waves 2 and 3, there was a significant decline in the proportion of smokers who reported “avoiding looking” at labels. Conclusions: This study found that implementation of PHWs in Mauritius significantly enhanced the effectiveness of warnings, illustrating their value for other countries, particularly in Africa, at an early stage in tobacco control. The study also demonstrates the importance of revising PHWs to counteract wearout. The introduction of PHWs in Mauritius clearly demonstrates the benefits of employing an evidence-based approach to strengthen tobacco control policies. PMID:24747120

  20. Paradoxical Effects of Warning in the Production of Children's False Memories

    ERIC Educational Resources Information Center

    Del Prete, Francesco; Mirandola, Chiara; Konishi, Mahiko; Cornoldi, Cesare; Ghetti, Simona

    2014-01-01

    The effects of warning on false recognition and associated subjective experience of false recollection and familiarity were investigated in 7-to 13-year-old children and young adults (N = 259) using the Deese-Roediger-McDermott (DRM) paradigm. Two warning conditions (warning with an example of a critical lure and warning without an example of a…

  1. Is the Effectiveness of Tobacco Image-Based Warning Labels Likely to Vary by Socio-Demographic Variable? Findings from an Online Survey of 19,000 Members of the UK Public

    ERIC Educational Resources Information Center

    Styles, Maggie; Williams, Brian; Humphris, Gerry

    2013-01-01

    Objective: Smoking continues to be a major global cause of mortality and morbidity. Countries have increasingly adopted the use of images as warnings on cigarette packs. We aimed to investigate the likely differential impact of varied images and messages on sub-groups of the United Kingdom (UK) smoking population. Methods: Forty two images…

  2. Earthquake Early Warning: User Education and Designing Effective Messages

    NASA Astrophysics Data System (ADS)

    Burkett, E. R.; Sellnow, D. D.; Jones, L.; Sellnow, T. L.

    2014-12-01

    The U.S. Geological Survey (USGS) and partners are transitioning from test-user trials of a demonstration earthquake early warning system (ShakeAlert) to deciding and preparing how to implement the release of earthquake early warning information, alert messages, and products to the public and other stakeholders. An earthquake early warning system uses seismic station networks to rapidly gather information about an occurring earthquake and send notifications to user devices ahead of the arrival of potentially damaging ground shaking at their locations. Earthquake early warning alerts can thereby allow time for actions to protect lives and property before arrival of damaging shaking, if users are properly educated on how to use and react to such notifications. A collaboration team of risk communications researchers and earth scientists is researching the effectiveness of a chosen subset of potential earthquake early warning interface designs and messages, which could be displayed on a device such as a smartphone. Preliminary results indicate, for instance, that users prefer alerts that include 1) a map to relate their location to the earthquake and 2) instructions for what to do in response to the expected level of shaking. A number of important factors must be considered to design a message that will promote appropriate self-protective behavior. While users prefer to see a map, how much information can be processed in limited time? Are graphical representations of wavefronts helpful or confusing? The most important factor to promote a helpful response is the predicted earthquake intensity, or how strong the expected shaking will be at the user's location. Unlike Japanese users of early warning, few Californians are familiar with the earthquake intensity scale, so we are exploring how differentiating instructions between intensity levels (e.g., "Be aware" for lower shaking levels and "Drop, cover, hold on" at high levels) can be paired with self-directed supplemental information to increase the public's understanding of earthquake shaking and protective behaviors.

  3. Patterns of combustible tobacco use in U.S. young adults and potential response to graphic cigarette health warning labels.

    PubMed

    Villanti, Andrea C; Pearson, Jennifer L; Cantrell, Jennifer; Vallone, Donna M; Rath, Jessica M

    2015-03-01

    In the evolving landscape of tobacco use, it remains unclear how tobacco control efforts should be designed and promoted for maximum impact. The current study links the identification of latent classes of young adult combustible tobacco users with anticipated responses to graphic health warning labels (HWLs). Data were collected in January 2012 using an online address-based panel as part of the Legacy Young Adult Cohort Study, and analyses were conducted in 2013. Latent class analyses identified five groups of tobacco users in a national sample of 4,236 young adults aged 18-34years: (1) little cigar/cigarillo/bidi (LCC) and hookah users (4%); (2) nonusers, open to smoking (3%); (3) daily smokers who self-identify as "smokers" (11%); (4) nondaily, light smokers who self-identify as "social or occasional smokers" (9%); and (5) nonusers closed to smoking (73%). Of the nonusers closed to smoking, 23% may be better characterized as at risk for tobacco initiation. Results indicate differences in the potential effectiveness of HWLs across classes. Compared to the daily "smokers," LCC and hookah users (RRR=2.35) and nonusers closed to smoking (RRR=2.33) were more than twice as likely to report that new graphic HWLs would make them think about not smoking. This study supports the potential of graphic HWLs to prevent young nonusers from using tobacco products. It suggests that the extension of prominent HWLs to other tobacco products, including LCCs and hookah tobacco, may also serve a prevention function. PMID:25437268

  4. 21 CFR 101.17 - Food labeling warning, notice, and safe handling statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82... use in reducing weight shall bear the following warning: WARNING: Very low calorie protein diets (below 400 Calories per day) may cause serious illness or death. Do Not Use for Weight Reduction in...

  5. 21 CFR 101.17 - Food labeling warning, notice, and safe handling statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82... use in reducing weight shall bear the following warning: WARNING: Very low calorie protein diets (below 400 Calories per day) may cause serious illness or death. Do Not Use for Weight Reduction in...

  6. 21 CFR 101.17 - Food labeling warning, notice, and safe handling statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82... use in reducing weight shall bear the following warning: WARNING: Very low calorie protein diets (below 400 Calories per day) may cause serious illness or death. Do Not Use for Weight Reduction in...

  7. 21 CFR 101.17 - Food labeling warning, notice, and safe handling statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82... use in reducing weight shall bear the following warning: WARNING: Very low calorie protein diets (below 400 Calories per day) may cause serious illness or death. Do Not Use for Weight Reduction in...

  8. 21 CFR 101.17 - Food labeling warning, notice, and safe handling statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-depleting substance designated by the Environmental Protection Agency (EPA) are set forth in 40 CFR part 82... use in reducing weight shall bear the following warning: WARNING: Very low calorie protein diets (below 400 Calories per day) may cause serious illness or death. Do Not Use for Weight Reduction in...

  9. The Use of Vivid Stimuli to Enhance Comprehension of the Content of Product Warning Messages.

    ERIC Educational Resources Information Center

    Kelley, Craig A.; And Others

    1989-01-01

    Two levels of vividness and three levels of motivation were measured in reactions to product label warnings. Vivid product warnings proved to be an effective tool to communicate the hazards associated with product use. (JOW)

  10. Improved Label and Liver Warning for Nonprescription Acetaminophen Products ! Acetaminophen is safe for self-care when used as directed, but has a

    E-print Network

    Martin, Gail

    Improved Label and Liver Warning for Nonprescription Acetaminophen Products BACKGROUND,2 ! Acetaminophen-related overdose is currently the number one cause of acute liver failure, and is a leading cause of liver transplant in the United States.2,3 ! Appropriate labeling of the over-the-counter (OTC) Drug

  11. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... warning statement shall be the standard chemical name of the substance as listed in 40 CFR part 82... greater than. 1 Minimum height of printed image of letters. (2) Alternative placement. The minimum...

  12. Cigarette Graphic Warning Labels and Smoking Prevalence in Canada: A Critical Examination and Reformulation of the FDA Regulatory Impact Analysis

    PubMed Central

    Huang, Jidong; Chaloupka, Frank J.; Fong, Geoffrey T.

    2014-01-01

    Background The estimated effect of cigarette graphic warning labels (GWLs) on smoking rates is a key input to FDA's regulatory impact analysis (RIA), required by law as part of its rulemaking process. However, evidence on the impact of GWLs on smoking prevalence is scarce. Objective The goal of this paper is to critically analyze FDA's approach to estimating the impact of GWLs on smoking rates in its RIA, and to suggest a path forward to estimating the impact of the adoption of GWLs in Canada on Canadian national adult smoking prevalence. Methods A quasi-experimental methodology was employed to examine the impact of adoption of GWLs in Canada in 2000, using the U.S. as a control. Findings We found a statistically significant reduction in smoking rates after the adoption of GWLs in Canada in comparison to the U.S. Our analyses show that implementation of GWLs in Canada reduced smoking rates by 2.87 to 4.68 percentage points, a relative reduction of 12.1 to 19.6% — 33 to 53 times larger than FDA's estimates of a 0.088 percentage point reduction. We also demonstrated that FDA's estimate of the impact was flawed because it is highly sensitive to the changes in variable selection, model specification, and the time period analyzed. Conclusions Adopting GWLs on cigarette packages reduces smoking prevalence. Applying our analysis of the Canadian GWLs, we estimate that if the U.S. had adopted GWLs in 2012, the number of adult smokers in the U.S. would have decreased by 5.3 to 8.6 million in 2013. Our analysis demonstrates that FDA's approach to estimating the impact of GWLs on smoking rates is flawed. Rectifying these problems before this approach becomes the norm is critical for FDA's effective regulation of tobacco products. PMID:24218057

  13. The communication triangle: elements of an effective warning message

    SciTech Connect

    Vaught, C.; Brnich, M.J. Jr.; Mallett, L.

    2007-01-15

    The lack of good communication is a very real problem in mine emergencies. To counter communication breakdowns, researchers at the NIOSH Pittsburgh Research Laboratory developed the Emergency Communication Triangle. It is a training intervention designed to help those giving a warning to provide the right sort of information and those receiving a warning to ask the right questions. The Triangle has six ordered components with the first three considered most important. The Emergency Communication is packaged as a short safety talk to be given by supervisors at the start of a shift. It was first tested in 1998 with a group of 236 workers at an underground mine in Colorado, and proved effective. It was followed up in 2003 and again in 2004. Now, more than half the miners would report who was affected by an event, 60% would report in its severity, and 70% would say what had been done so far. 3 figs.

  14. Adolescents' Attention to Traditional and Graphic Tobacco Warning Labels: An Eye-Tracking Approach

    ERIC Educational Resources Information Center

    Peterson, Emily Bylund; Thomsen, Steven; Lindsay, Gordon; John, Kevin

    2010-01-01

    The objective of this study was determine if the inclusion of Canadian-style graphic images would improve the degree to which adolescents attend to, and subsequently are able to recall, novel warning messages in tobacco magazine advertising. Specifically, our goal was to determine if the inclusion of graphic images would 1) increase visual…

  15. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... warning statement shall be the standard chemical name of the substance as listed in 40 CFR part 82, appendix A to subpart A, except that: (1) The acronym “CFC” may be substituted for “chlorofluorocarbon.” (2) The acronym “HCFC” may be substituted for “hydrochlorofluorocarbon.” (3) The term...

  16. 40 CFR 82.110 - Form of label bearing warning statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... warning statement shall be the standard chemical name of the substance as listed in 40 CFR part 82, appendix A to subpart A, except that: (1) The acronym “CFC” may be substituted for “chlorofluorocarbon.” (2) The acronym “HCFC” may be substituted for “hydrochlorofluorocarbon.” (3) The term...

  17. The Effect of Sonic Booms on Earthquake Warning Systems

    NASA Technical Reports Server (NTRS)

    Wurman, Gilead; Haering, Edward A, Jr.; Price, Michael J.

    2011-01-01

    Several aerospace companies are designing quiet supersonic business jets for service over the United States. These aircraft have the potential to increase the occurrence of mild sonic booms across the country. This leads to interest among earthquake warning (EQW) developers and the general seismological community in characterizing the effect of sonic booms on seismic sensors in the field, their potential impact on EQW systems, and means of discriminating their signatures from those of earthquakes. The SonicBREWS project (Sonic Boom Resistant Earthquake Warning Systems) is a collaborative effort between Seismic Warning Systems, Inc. (SWS) and NASA Dryden Flight Research Center. This project aims to evaluate the effects of sonic booms on EQW sensors. The study consists of exposing high-sample-rate (1000 sps) triaxial accelerometers to sonic booms with overpressures ranging from 10 to 600 Pa in the free field and the built environment. The accelerometers record the coupling of the sonic boom to the ground and surrounding structures, while microphones record the acoustic wave above ground near the sensor. Sonic booms are broadband signals with more high-frequency content than earthquakes. Even a 1000 sps accelerometer will produce a significantly aliased record. Thus the observed peak ground velocity is strongly dependent on the sampling rate, and increases as the sampling rate is reduced. At 1000 sps we observe ground velocities that exceed those of P-waves from ML 3 earthquakes at local distances, suggesting that sonic booms are not negligible for EQW applications. We present the results of several experiments conducted under SonicBREWS showing the effects of typical-case low amplitude sonic booms and worst-case high amplitude booms. We show the effects of various sensor placements and sensor array geometries. Finally, we suggest possible avenues for discriminating sonic booms from earthquakes for the purposes of EQW.

  18. Effects of Single versus Multiple Warnings on Driver Performance

    E-print Network

    Cummings, M. L.

    2007-01-01

    Objective: To explore how a single master alarm system affects drivers’ responses when compared to multiple, distinct warnings. Background: Advanced driver warning systems are intended to improve safety, yet inappropriate ...

  19. Effect of Graphic Cigarette Warnings on Smoking Intentions in Young Adults

    PubMed Central

    Blanton, Hart; Snyder, Leslie B.; Strauts, Erin; Larson, Joy G.

    2014-01-01

    Introduction Graphic warnings (GWs) on cigarette packs are widely used internationally and perhaps will be in the US but their impact is not well understood. This study tested support for competing hypotheses in different subgroups of young adults defined by their history of cigarette smoking and individual difference variables (e.g., psychological reactance). One hypothesis predicted adaptive responding (GWs would lower smoking-related intentions) and another predicted defensive responding (GWs would raise smoking-related intentions). Methods Participants were an online sample of 1,169 Americans ages 18–24, who were randomly assigned either to view nine GWs designed by the FDA or to a no-label control. Both the intention to smoke in the future and the intention to quit smoking (among smokers) were assessed before and after message exposure. Results GWs lowered intention to smoke in the future among those with a moderate lifetime smoking history (between 1 and 100 cigarettes), and they increased intention to quit smoking among those with a heavy lifetime smoking history (more than 100 cigarettes). Both effects were limited to individuals who had smoked in some but not all of the prior 30 days (i.e., occasional smokers). No evidence of defensive “boomerang effects” on intention was observed in any subgroup. Conclusion Graphic warnings can reduce interest in smoking among occasional smokers, a finding that supports the adaptive-change hypothesis. GWs that target occasional smokers might be more effective at reducing cigarette smoking in young adults. PMID:24806481

  20. When Health Policy and Empirical Evidence Collide: The Case of Cigarette Package Warning Labels and Economic Consumer Surplus

    PubMed Central

    Song, Anna V.; Brown, Paul

    2014-01-01

    In its graphic warning label regulations on cigarette packages, the Food and Drug Administration severely discounts the benefits of reduced smoking because of the lost “pleasure” smokers experience when they stop smoking; this is quantified as lost “consumer surplus.” Consumer surplus is grounded in rational choice theory. However, empirical evidence from psychological cognitive science and behavioral economics demonstrates that the assumptions of rational choice are inconsistent with complex multidimensional decisions, particularly smoking. Rational choice does not account for the roles of emotions, misperceptions, optimistic bias, regret, and cognitive inefficiency that are germane to smoking, particularly because most smokers begin smoking in their youth. Continued application of a consumer surplus discount will undermine sensible policies to reduce tobacco use and other policies to promote public health. PMID:24328661

  1. The Impact of Graphic Cigarette Warning Labels and Smoke-Free Law on Health Awareness and Thoughts of Quitting in Taiwan

    ERIC Educational Resources Information Center

    Chang, Fong-Ching; Chung, Chi-Hui; Yu, Po-Tswen; Chao, Kun-yu

    2011-01-01

    The present study evaluated the impact of Taiwan's graphic cigarette warning labels and smoke-free law on awareness of the health hazards of smoking and thoughts of quitting smoking. National representative samples of 1074 and 1094 people, respectively, were conducted successfully by telephone in July 2008 (pre-law) and March 2009 (post-law).…

  2. Off-Label Prescribing, Polypharmacy, and Black-Box Warnings: A Primer for School Psychologists

    ERIC Educational Resources Information Center

    Shahidullah, Jeffrey D.

    2012-01-01

    Psychotropic medications are increasingly used to treat children and adolescents with mental health conditions. Between the years 1994 and 2001, there was a 191.7% increase in number of office visits resulting in a psychotropic medication prescription among children and adolescents. Many drugs are prescribed to children "off-label", whereby they…

  3. Examining the conspicuousness and prominence of two required warnings on OTC pain relievers

    PubMed Central

    Bix, Laura; Bello, Nora M.; Auras, Rafael; Ranger, Jon; Lapinski, Maria K.

    2009-01-01

    The labeling of over-the-counter (OTC) drugs is critical to their safe and effective use, and certain warnings are meant to be read at the point of purchase (POP). Examples include (i) warnings that alert consumers to the fact that the package is not child-resistant and (ii) warnings that alert consumers to potential product tampering. U.S. law mandates these warnings be “conspicuous” and “prominent” so that it is likely that consumers will read them before leaving the store. Our objective was to quantify the relative prominence and conspicuousness of these warnings. Sixty-one participants reviewed the packages of 5 commercially available analgesics to evaluate the prominence and conspicuousness of these warnings. Evaluated data included (i) the time spent examining the warnings compared with other areas of the label (using a bright pupil eye tracker), (ii) the ability to recall information from the OTCs viewed, and (iii) the legibility of the warnings relative to other elements of the labels (as measured by ASTM D7298-06). Eye-tracking data indicated that warnings were viewed by fewer participants and for less time than other elements of the packages. Recall and legibility data also indicated that the warning statements compared unfavorably with other elements of the labels tested. Evidence presented in this study suggests that 2 required warnings on 5 different OTCs are not prominent or conspicuous when compared with other elements of tested labels. PMID:19332798

  4. Response time effects of alerting tone and semantic context for synthesized voice cockpit warnings

    NASA Technical Reports Server (NTRS)

    Simpson, C. A.; Williams, D. H.

    1980-01-01

    Some handbooks and human factors design guides have recommended that a voice warning should be preceded by a tone to attract attention to the warning. As far as can be determined from a search of the literature, no experimental evidence supporting this exists. A fixed-base simulator flown by airline pilots was used to test the hypothesis that the total 'system-time' to respond to a synthesized voice cockpit warning would be longer when the message was preceded by a tone because the voice itself was expected to perform both the alerting and the information transfer functions. The simulation included realistic ATC radio voice communications, synthesized engine noise, cockpit conversation, and realistic flight routes. The effect of a tone before a voice warning was to lengthen response time; that is, responses were slower with an alerting tone. Lengthening the voice warning with another work, however, did not increase response time.

  5. An evaluation of the FDA's analysis of the costs and benefits of the graphic warning label regulation

    PubMed Central

    Chaloupka, Frank J; Warner, Kenneth E; Acemo?lu, Daron; Gruber, Jonathan; Laux, Fritz; Max, Wendy; Newhouse, Joseph; Schelling, Thomas; Sindelar, Jody

    2015-01-01

    The Family Smoking Prevention and Tobacco Control Act of 2009 gave the Food and Drug Administration (FDA) regulatory authority over cigarettes and smokeless tobacco products and authorised it to assert jurisdiction over other tobacco products. As with other Federal agencies, FDA is required to assess the costs and benefits of its significant regulatory actions. To date, FDA has issued economic impact analyses of one proposed and one final rule requiring graphic warning labels (GWLs) on cigarette packaging and, most recently, of a proposed rule that would assert FDA’s authority over tobacco products other than cigarettes and smokeless tobacco. Given the controversy over the FDA's approach to assessing net economic benefits in its proposed and final rules on GWLs and the importance of having economic impact analyses prepared in accordance with sound economic analysis, a group of prominent economists met in early 2014 to review that approach and, where indicated, to offer suggestions for an improved analysis. We concluded that the analysis of the impact of GWLs on smoking substantially underestimated the benefits and overestimated the costs, leading the FDA to substantially underestimate the net benefits of the GWLs. We hope that the FDA will find our evaluation useful in subsequent analyses, not only of GWLs but also of other regulations regarding tobacco products. Most of what we discuss applies to all instances of evaluating the costs and benefits of tobacco product regulation and, we believe, should be considered in FDA's future analyses of proposed rules. PMID:25550419

  6. Promoting cessation resources through cigarette package warning labels: a longitudinal survey with adult smokers in Canada, Australia and Mexico

    PubMed Central

    Thrasher, James F; Osman, Amira; Moodie, Crawford; Hammond, David; Bansal-Travers, Maansi; Cummings, K Michael; Borland, Ron; Yong, Hua-Hie; Hardin, James

    2015-01-01

    Introduction Health warning labels (HWLs) on tobacco packaging can be used to provide smoking cessation information, but the impact of this information is not well understood. Methods Online consumer panels of adult smokers from Canada, Australia and Mexico were surveyed in September 2012, January 2013 and May 2013; replenishment was used to maintain sample sizes of 1000 participants in each country at each wave. Country-stratified logistic Generalised Estimating Equation (GEE) models were estimated to assess correlates of citing HWLs as a source of information on quitlines and cessation websites. GEE models also regressed having called the quitline, and having visited a cessation website, on awareness of these resources because of HWLs. Results At baseline, citing HWLs as a source of information about quitlines was highest in Canada, followed by Australia and Mexico (33%, 19% and 16%, respectively). Significant increases over time were only evident in Australia and Mexico. In all countries, citing HWLs as a source of quitline information was significantly associated with self-report of having called a quitline. At baseline, citing HWLs as a source of information about cessation websites was higher in Canada than in Australia (14% and 6%, respectively; Mexico was excluded because HWLs do not include website information), but no significant changes over time were found for either country. Citing HWLs as a source of information about cessation websites was significantly associated with having visited a website in both Canada and Australia. Conclusions HWLs are an important source of cessation information. PMID:25052860

  7. An evaluation of the FDA's analysis of the costs and benefits of the graphic warning label regulation.

    PubMed

    Chaloupka, Frank J; Warner, Kenneth E; Acemo?lu, Daron; Gruber, Jonathan; Laux, Fritz; Max, Wendy; Newhouse, Joseph; Schelling, Thomas; Sindelar, Jody

    2015-03-01

    The Family Smoking Prevention and Tobacco Control Act of 2009 gave the Food and Drug Administration (FDA) regulatory authority over cigarettes and smokeless tobacco products and authorised it to assert jurisdiction over other tobacco products. As with other Federal agencies, FDA is required to assess the costs and benefits of its significant regulatory actions. To date, FDA has issued economic impact analyses of one proposed and one final rule requiring graphic warning labels (GWLs) on cigarette packaging and, most recently, of a proposed rule that would assert FDA's authority over tobacco products other than cigarettes and smokeless tobacco. Given the controversy over the FDA's approach to assessing net economic benefits in its proposed and final rules on GWLs and the importance of having economic impact analyses prepared in accordance with sound economic analysis, a group of prominent economists met in early 2014 to review that approach and, where indicated, to offer suggestions for an improved analysis. We concluded that the analysis of the impact of GWLs on smoking substantially underestimated the benefits and overestimated the costs, leading the FDA to substantially underestimate the net benefits of the GWLs. We hope that the FDA will find our evaluation useful in subsequent analyses, not only of GWLs but also of other regulations regarding tobacco products. Most of what we discuss applies to all instances of evaluating the costs and benefits of tobacco product regulation and, we believe, should be considered in FDA's future analyses of proposed rules. PMID:25550419

  8. Assessing the impact of cigarette package health warning labels: a cross-country comparison in Brazil, Uruguay, and Mexico

    PubMed Central

    Thrasher, James F; Villalobos, Victor; Szklo, André; Fong, Geoffrey T; Pérez, Cristina; Sebrié, Ernesto; Sansone, Natalie; Figueiredo, Valeska; Boado, Marcelo; Arillo-Santillán, Edna; Bianco, Eduardo

    2015-01-01

    Objective To assess the impact of different health warning labels (HWL). Material and Methods Data from the International Tobacco Control Survey (ITC Survey) were analyzed from adult smokers in Brazil, Uruguay and Mexico, each of which used a different HWL strategy (pictures of human suffering and diseased organs; abstract pictorial representations of risk; and text-only messages, respectively). Main outcomes were HWL salience and cognitive impact. Results HWLs in Uruguay (which was the only country with a HWL on the front of the package) had higher salience than either Brazilian or Mexican packs. People at higher levels of educational attainment in Mexico were more likely to read the text-only HWLs whereas education was unassociated with salience in Brazil or Uruguay. Brazilian HWLs had greater cognitive impacts than HWLs in either Uruguay or Mexico. HWLs in Uruguay generated lower cognitive impacts than the text-only HWLs in Mexico. In Brazil, cognitive impacts were strongest among smokers with low educational attainment. Conclusions This study suggests that HWLs have the most impact when they are prominent (i.e., front and back of the package) and include emotionally engaging imagery that illustrates negative bodily impacts or human suffering due to smoking. PMID:21243191

  9. The effect of warnings on false memories in young and older adults.

    PubMed

    McCabe, David P; Smith, Anderson D

    2002-10-01

    In the present experiments, we examined adult age differences in the ability to suppress false memories, using the Deese-Roediger-McDermott (DRM) paradigm (Deese, 1959; Roediger & McDermott, 1995). Participants studied lists of words (e.g., bed, rest, awake, etc.), each related to a nonpresented critical lure word (e.g., sleep). Typically, recognition tests reveal false alarms to critical lures at rates comparable to those for hits for studied words. In two experiments, separate groups of young and older adults were unwarned about the false memory effect, warned before studying the lists, or warned after study and before test. Lists were presented at either a slow rate (4 sec/word) or a faster rate (2 sec/word). Young adults were better able to discriminate between studied words and critical lures when warned about the DRM effect either before study or after study but before retrieval, and their performance improved with a slower presentation rate. Older adults were able to discriminate between studied words and critical lures when given warnings before study, but not when given warnings after study but before retrieval. Performance on a working memory capacity measure predicted false recognition following study and retrieval warnings. The results suggest that effective use of warnings to reduce false memories is contingent on the quality and type of encoded information, as well as on whether that information is accessed at retrieval. Furthermore, discriminating between similar sources of activation is dependent on working memory capacity, which declines with advancing age. PMID:12507371

  10. Exposure to Prescription Drugs Labeled for Risk of Adverse Effects of Suicidal Behavior or Ideation among 100 Air Force Personnel Who Died by Suicide, 2006-2009

    ERIC Educational Resources Information Center

    Lavigne, Jill E.; McCarthy, Michael; Chapman, Richard; Petrilla, Allison; Knox, Kerry L.

    2012-01-01

    Prescription drugs for many indications are labeled with warnings for potential risk of suicidal ideation or behavior. Exposures to prescription drugs labeled for adverse effects of suicidal behavior or ideation among 100 Air Force personnel who died by suicide between 2006 and 2009 are described. Air Force registry data were linked to…

  11. Effects of Shared Electronic Health Record Systems on Drug-Drug Interaction and Duplication Warning Detection.

    PubMed

    Rinner, Christoph; Grossmann, Wilfried; Sauter, Simone Katja; Wolzt, Michael; Gall, Walter

    2015-01-01

    Shared electronic health records (EHRs) systems can offer a complete medication overview of the prescriptions of different health care providers. We use health claims data of more than 1 million Austrians in 2006 and 2007 with 27 million prescriptions to estimate the effect of shared EHR systems on drug-drug interaction (DDI) and duplication warnings detection and prevention. The Austria Codex and the ATC/DDD information were used as a knowledge base to detect possible DDIs. DDIs are categorized as severe, moderate, and minor interactions. In comparison to the current situation where only DDIs between drugs issued by a single health care provider can be checked, the number of warnings increases significantly if all drugs of a patient are checked: severe DDI warnings would be detected for 20% more persons, and the number of severe DDI warnings and duplication warnings would increase by 17%. We show that not only do shared EHR systems help to detect more patients with warnings but DDIs are also detected more frequently. Patient safety can be increased using shared EHR systems. PMID:26682218

  12. Effects of Shared Electronic Health Record Systems on Drug-Drug Interaction and Duplication Warning Detection

    PubMed Central

    Rinner, Christoph; Grossmann, Wilfried; Sauter, Simone Katja; Wolzt, Michael; Gall, Walter

    2015-01-01

    Shared electronic health records (EHRs) systems can offer a complete medication overview of the prescriptions of different health care providers. We use health claims data of more than 1 million Austrians in 2006 and 2007 with 27 million prescriptions to estimate the effect of shared EHR systems on drug-drug interaction (DDI) and duplication warnings detection and prevention. The Austria Codex and the ATC/DDD information were used as a knowledge base to detect possible DDIs. DDIs are categorized as severe, moderate, and minor interactions. In comparison to the current situation where only DDIs between drugs issued by a single health care provider can be checked, the number of warnings increases significantly if all drugs of a patient are checked: severe DDI warnings would be detected for 20% more persons, and the number of severe DDI warnings and duplication warnings would increase by 17%. We show that not only do shared EHR systems help to detect more patients with warnings but DDIs are also detected more frequently. Patient safety can be increased using shared EHR systems. PMID:26682218

  13. Developing effective warning systems: Ongoing research at Ruapehu volcano, New Zealand

    NASA Astrophysics Data System (ADS)

    Leonard, Graham S.; Johnston, David M.; Paton, Douglas; Christianson, Amy; Becker, Julia; Keys, Harry

    2008-05-01

    PurposeThis paper examines the unique challenges to volcanic risk management associated with having a ski area on an active volcano. Using a series of simulated eruption/lahar events at Ruapehu volcano, New Zealand, as a context, a model of risk management that integrates warning system design and technology, risk perceptions and the human response is explored. Principal resultsDespite increases in the observed audibility and comprehension of the warning message, recall of public education content, and people's awareness of volcanic risk, a persistent minority of the public continued to demonstrate only moderate awareness of the correct actions to take during a warning and failed to respond effectively. A relationship between level of staff competence and correct public response allowed the level of public response to be used to identify residual risk and additional staff training needs. The quality of staff awareness, action and decision-making has emerged as a critical factor, from detailed staff and public interviews and from exercise observations. Staff actions are especially important for mobilising correct public response at Ruapehu ski areas due to the transient nature of the visitor population. Introduction of education material and staff training strategies that included the development of emergency decision-making competencies improved knowledge of correct actions, and increased the proportion of people moving out of harm's way during blind tests. Major conclusionsWarning effectiveness is a function of more than good hazard knowledge and the generation and notification of an early warning message. For warning systems to be effective, these factors must be complemented by accurate knowledge of risk and risk management actions. By combining the Ruapehu findings with those of other warning system studies in New Zealand, and internationally, a practical five-step model for effective early warning systems is discussed. These steps must be based upon sound and regularly updated underpinning science and be tied to formal effectiveness evaluation, which is fed back into system improvements. The model presented emphasises human considerations, the development of which arguably require even more effort than the hardware components of early warning systems.

  14. Abandoning a label doesn’t make it disappear: The perseverance of labeling effects

    PubMed Central

    Foroni, Francesco; Rothbart, Myron

    2012-01-01

    Labels exert strong influence on perception and judgment. The present experiment examines the possibility that such effects may persist even when labels are abandoned. Participants judged the similarity of pairs of silhouette drawings of female body types, ordered on a continuum from very thin to very heavy, under conditions where category labels were, and were not, superimposed on the ordered stimuli. Consistent with earlier research, labels had strong effects on perceived similarity, with silhouettes sharing the same label judged as more similar than those having different labels. Moreover, when the labels were removed and no longer present, the effect of the labels, although diminished, persisted. It did not make any difference whether the labels were simply abandoned or, in addition, had their validity challenged. The results are important for our understanding of categorization and labeling processes. The potential theoretical and practical implications of these results for social processes are discussed. PMID:23105148

  15. Synthesized speech rate and pitch effects on intelligibility of warning messages for pilots

    NASA Technical Reports Server (NTRS)

    Simpson, C. A.; Marchionda-Frost, K.

    1984-01-01

    In civilian and military operations, a future threat-warning system with a voice display could warn pilots of other traffic, obstacles in the flight path, and/or terrain during low-altitude helicopter flights. The present study was conducted to learn whether speech rate and voice pitch of phoneme-synthesized speech affects pilot accuracy and response time to typical threat-warning messages. Helicopter pilots engaged in an attention-demanding flying task and listened for voice threat warnings presented in a background of simulated helicopter cockpit noise. Performance was measured by flying-task performance, threat-warning intelligibility, and response time. Pilot ratings were elicited for the different voice pitches and speech rates. Significant effects were obtained only for response time and for pilot ratings, both as a function of speech rate. For the few cases when pilots forgot to respond to a voice message, they remembered 90 percent of the messages accurately when queried for their response 8 to 10 sec later.

  16. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1...Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement...

  17. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1...Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement...

  18. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1...Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement...

  19. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1...Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement...

  20. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1...Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement...

  1. Perceived effectiveness of pictorial health warnings among Mexican youth and adults: a population-level intervention to reduce tobacco related inequities

    PubMed Central

    Hammond, David; Thrasher, James; Reid, Jessica L.; Driezen, Pete; Boudreau, Christian; Santillan, Edna Arillo

    2015-01-01

    Purpose Pictorial health warnings on cigarette packages are a prominent and effective means of communicating the risks of smoking; however, there is little research on effective types of message content and socio-demographic effects. This study tested message themes and content of pictorial warnings in Mexico. Methods Face-to-face surveys were conducted with 544 adult smokers and 528 youth in Mexico City. Participants were randomized to view 5–7 warnings for two of 15 different health effects. Warnings for each health effect included a text-only warning and pictorial warnings with various themes: “graphic” health effects, “lived experience”, symbolic images, and testimonials. Results Pictorial health warnings were rated as more effective than text-only warnings. Pictorial warnings featuring “graphic” depictions of disease were significantly more effective than symbolic images or experiences of human suffering. Adding testimonial information to warnings increased perceived effectiveness. Adults who were female, older, had lower education, and intended to quit smoking rated warnings as more effective, although the magnitude of these differences was modest. Few interactions were observed between socio-demographics and message theme. Conclusions Graphic depictions of disease were perceived by youth and adults as the most effective warning theme. Perceptions of warnings were generally similar across socio-demographic groups. PMID:22362058

  2. The Effects of Tobacco-Related Health-Warning Images on Intention to Quit Smoking among Urban Chinese Smokers

    ERIC Educational Resources Information Center

    Wu, Dan; Yang, Tingzhong; Cottrell, Randall R.; Zhou, Huan; Yang, Xiaozhao Y.; Zhang, Yanqin

    2015-01-01

    Objective: The purpose of this study was to explore the effects of different tobacco health-warning images on intention to quit smoking among urban Chinese smokers. The different tobacco health-warning images utilised in this study addressed the five variables of age, gender, cultural-appropriateness, abstractness and explicitness. Design:…

  3. Effects of culture (China vs. US) and task on perceived hazard: Evidence from product ratings, label ratings, and product to label matching.

    PubMed

    Lesch, Mary F; Rau, Pei-Luen Patrick; Choi, YoonSun

    2016-01-01

    In the current study, 44 Chinese and 40 US college students rated their perceived hazard in response to warning labels and products and attempted to match products with warning labels communicating the same level of hazard. Chinese participants tended to provide lower ratings of hazard in response to labels, but hazard perceived in response to products did not significantly differ as a function of culture. When asked to match a product with a warning label, Chinese participants' hazard perceptions appeared to be better calibrated, than did US participants', across products and labels. The results are interpreted in terms of constructivist theory which suggests that risk perceptions vary depending on the "frame of mind" evoked by the environment/context. Designers of warnings must be sensitive to the fact that product users' cognitive representations develop within a culture and that risk perceptions will vary based on the context in which they are derived. PMID:26360193

  4. Effects of Labels on Visual Perceptions 

    E-print Network

    Lara, Frankie

    2009-06-09

    of rules. Cognition, 65, 263-297. Willadsen-Jensen, E.C., & Ito, T. A., (2008). A foot in both worlds: Asian Americans? perceptions of Asian, White, and racially ambiguous faces. Group Processes & Intergroup Relations, 11, 182-200. Markman, E. M...-1 EFFECTS OF LABELS ON VISUAL PERCEPTIONS Major: Psychology April 2009 Submitted to the Office of Undergraduate Research Texas A&M University in partial fulfillment of the requirements for the designation as UNDERGRADUATE RESEARCH SCHOLAR A Senior...

  5. Effects of label distinctiveness and label testing on recognition of complex pictures.

    PubMed

    Bartlett, J C; Till, R E; Fields, W C

    1980-09-01

    Two experiments examined the effects of label retrieval upon subsequent recognition of complex, scenic pictures. Contrary to past research, i.e., Bahrick and Boucher's 1968 study, retrieval of labels which accompanied pictures at input was associated with high recognition of "same-photo" (copy) cues but not false recognition of similar "same-scene" cues on a subsequent "photo" recognition test. The label-retrieval effect can be attributed to actual rehearsal of pictorial information and not to item selection. In addition, the beneficial effects of label retrieval did not vary with the informational content of the label itself, i.e., its power to distinguish between same-photo and same-scene items. However, the effects of label-type as well as label retrieval varied with recognition test instructions. In a "scene" recognition test, requiring recognition of both same-photo and same-scene items, effects of label-type were stronger than in the "photo" test, while effects of label retrieval were not significant. The results highlight the complexity of the relationships between label retrieval and picture recognition and suggest several factors which might determine such relationships. PMID:7212128

  6. Use of an auditory signal in a rear-end collision warning system: effects on braking force and reaction time 

    E-print Network

    Hopkins, Jennifer Susan

    1995-01-01

    This simulator experiment is a preliminary study examining the effects of different auditory signals on braking force and reaction time in a rear-end collision warning system. A driving simulator was built in which subjects operated a computer...

  7. The effect of colored borders and age on the conspicuity of warning signs in a complex visual environment 

    E-print Network

    Chard, Joshua Turner

    1993-01-01

    This laboratory study examined the effect of colored borders and age on the conspicuity of roadside warning signs embedded in cluttered urban environments. Prior research has suggested that a uniform border surrounding a ...

  8. Neural biomarkers for assessing different types of imagery in pictorial health warning labels for cigarette packaging: a cross-sectional study

    PubMed Central

    Newman-Norlund, Roger D; Thrasher, James F; Fridriksson, Johann; Brixius, William; Froeliger, Brett; Hammond, David; Cummings, Michael K

    2014-01-01

    Objective Countries around the world have increasingly adopted pictorial health warning labels (HWLs) for tobacco packages to warn consumers about smoking-related risks. Research on how pictorial HWLs work has primarily analysed self-reported responses to HWLs; studies at the neural level comparing the brain's response to different types of HWLs may provide an important complement to prior studies, especially if self-reported responses are systematically biased. In this study we characterise the brain's response to three types of pictorial HWLs for which prior self-report studies indicated different levels of efficacy. Methods Current smokers rated pictorial HWLs and then observed the same HWLs during functional MRI (fMRI) scanning. Fifty 18–50-year-old current adult smokers who were free from neurological disorders were recruited from the general population and participated in the study. Demographics, smoking-related behaviours and self-reported ratings of pictorial HWL stimuli were obtained prior to scanning. Brain responses to HWLs were assessed using fMRI, focusing on a priori regions of interest. Results Pictorial HWL stimuli elicited activation in a broad network of brain areas associated with visual processing and emotion. Participants who rated the stimuli as more emotionally arousing also showed greater neural responses at these sites. Conclusions Self-reported ratings of pictorial HWLs are correlated with neural responses in brain areas associated with visual and emotional processing. Study results cross-validate self-reported ratings of pictorial HWLs and provide insights into how pictorial HWLs are processed. PMID:25552613

  9. Memory Saves Lives: Inter-generational Warnings Effectiveness - 13556

    SciTech Connect

    Van Luik, Abraham; Patterson, Russell; Shafer, David; Klein, Thomas

    2013-07-01

    The 2011 Tohoku earthquake and tsunami was a world-class natural disaster. It has been described as the most powerful earthquake ever in Japan, and as one of the most powerful earthquakes ever noted in the world. The toll in terms of human lives lost and property destruction was unimaginable. Even the word 'horrible' is inadequate to describe the suffering and misery that resulted. Nations with nuclear power programs are engaged in, or at least planning to become engaged in, arranging to eventually dispose of their higher-level radioactive waste materials in deep geologic repositories. Geologic repositories are passive safety systems, and if undisturbed isolate these dangerous materials form the biosphere for extremely long times. The key words, however, are 'if undisturbed'. To assure that future generations do not inadvertently drill into repositories, national programs, and the international community (the Records, Knowledge and Memory (RK and M) preservation project of the Nuclear Energy Agency, for example), are proposing to place markers and/or monuments on closed repository sites that say 'do not drill here, and this is why' in various sophisticated ways. Such markers or monuments are attempts at providing passive institutional controls. The effectiveness of messages from past generations to a present generation may give an indication of how effective such passive institutional controls may be. (authors)

  10. Affect labeling enhances exposure effectiveness for public speaking anxiety.

    PubMed

    Niles, Andrea N; Craske, Michelle G; Lieberman, Matthew D; Hur, Christopher

    2015-05-01

    Exposure is an effective treatment for anxiety but many patients do not respond fully. Affect labeling (labeling emotional experience) attenuates emotional responding. The current project examined whether affect labeling enhances exposure effectiveness in participants with public speaking anxiety. Participants were randomized to exposure with or without affect labeling. Physiological arousal and self-reported fear were assessed before and after exposure and compared between groups. Consistent with hypotheses, participants assigned to Affect Labeling, especially those who used more labels during exposure, showed greater reduction in physiological activation than Control participants. No effect was found for self-report measures. Also, greater emotion regulation deficits at baseline predicted more benefit in physiological arousal from exposure combined with affect labeling than exposure alone. The current research provides evidence that behavioral strategies that target prefrontal-amygdala circuitry can improve treatment effectiveness for anxiety and these effects are particularly pronounced for patients with the greatest deficits in emotion regulation. PMID:25795524

  11. Tobacco industry argues domestic trademark laws and international treaties preclude cigarette health warning labels, despite consistent legal advice that the argument is invalid

    PubMed Central

    Crosbie, Eric; Glantz, Stanton A

    2013-01-01

    Objectives To analyse the tobacco industry’s use of international trade agreements to oppose policies to strengthen health warning labels (HWLs). Design A review of tobacco industry documents, tobacco control legislation and international treaties. Results During the early 1990s, the tobacco industry became increasingly alarmed about the advancement of HWLs on cigarettes packages. In response, it requested legal opinions from British American Tobacco’s law firms in Australia and England, Britain’s Department of Trade and Industry and the World Intellectual Property Organisation on the legality of restricting and prohibiting the use of their trademarks, as embodied in cigarette packages. The consistent legal advice, privately submitted to the companies, was that international treaties do not shield trademark owners from government limitations (including prohibition) on the use of their trademarks. Despite receiving this legal advice, the companies publicly argued that requiring large HWLs compromised their trademark rights under international treaties. The companies successfully used these arguments as part of their successful effort to deter Canadian and Australian governments from enacting laws requiring the plan packaging of cigarettes, which helped delay large graphic HWLs, including ‘plain’ packaging, for over a decade. Conclusions Governments should not be intimidated by tobacco company threats and unsubstantiated claims, and carefully craft HWL laws to withstand the inevitable tobacco industry lawsuits with the knowledge that the companies’ own lawyers as well as authoritative bodies have told the companies that the rights they claim do not exist. PMID:23179728

  12. The Fetal Alcohol Syndrome Public Awareness Campaign, 1979: Progress Report Concerning the Advance Notice of Proposed Rulemaking on Warning Labels on Containers of Alcoholic Beverages and Addendum.

    ERIC Educational Resources Information Center

    Department of the Treasury, Washington, DC.

    This report provides expert opinion on the problems of fetal alcohol syndrome (FAS) and ways to inform the public of teratogenic risk of alcohol consumption during pregnancy. In the absence of firm evidence that moderate drinking of alcoholic beverages leads to FAS and uncertainty concerning the effectiveness of labeling of alcoholic beverages, a…

  13. Smokers' recall of Australian graphic cigarette packet warnings & awareness of associated health effects, 2005-2008

    PubMed Central

    2011-01-01

    Background In 2006, Australia introduced graphic cigarette packet warnings. The new warnings include one of 14 pictures, many depicting tobacco-related pathology. The warnings were introduced in two sets; Set A in March and Set B from November. This study explores their impact on smokers' beliefs about smoking related illnesses. This study also examines the varying impact of different warnings, to see whether warnings with visceral images have greater impact on smokers' beliefs than other images. Methods Representative samples of South Australian smokers were interviewed in four independent cross-sectional omnibus surveys; in 2005 (n = 504), 2006 (n = 525), 2007 (n = 414) and 2008 (n = 464). Results Unprompted recall of new graphic cigarette warnings was high in the months following their introduction, demonstrating that smokers' had been exposed to them. Smokers also demonstrated an increase in awareness about smoking-related diseases specific to the warning messages. Warnings that conveyed new information and had emotive images demonstrated greater impact on recall and smokers' beliefs than more familiar information and less emotive images. Conclusions Overall graphic pack warnings have had the intended impact on smokers. Some have greater impact than others. The implications for policy makers in countries introducing similar warnings are that fresh messaging and visceral images have the greatest impact. PMID:21496314

  14. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2 Conspicuousness of warning... exemption pursuant to paragraph (b) of this section is established. (b) If the label of any cosmetic...

  15. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2 Conspicuousness of warning... exemption pursuant to paragraph (b) of this section is established. (b) If the label of any cosmetic...

  16. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2 Conspicuousness of warning... exemption pursuant to paragraph (b) of this section is established. (b) If the label of any cosmetic...

  17. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2 Conspicuousness of warning... exemption pursuant to paragraph (b) of this section is established. (b) If the label of any cosmetic...

  18. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2 Conspicuousness of warning... exemption pursuant to paragraph (b) of this section is established. (b) If the label of any cosmetic...

  19. A qualitative exploration of young adult smokers’ responses to novel tobacco warnings

    PubMed Central

    2013-01-01

    Background Despite reduced smoking among adolescents, smoking prevalence peaks among young adults aged 18–30, many of whom believe themselves exempt from the health risks of smoking shown in warning labels. We explored how young adult smokers perceived warnings featuring proximal risks, and whether these encouraged cessation more effectively than traditional health messages. Methods We conducted in-depth interviews with 17 young adult smokers and explored their perceptions of current warnings as well as novel warnings representing short-term health consequences; immediate social risks, and tobacco’s toxicity (denormalizing tobacco as an everyday product). We used a thematic analysis approach to explore how participants rationalized existing warnings and interpreted the novel messages. Results Participants considered the immediate social and physiological benefits they gained from smoking outweighed the distal risks shown in health warnings, which they regarded as improbable and irrelevant. Of the novel warnings, those presenting immediate social risks altered the balance of gains and losses young adults associated with smoking; however, those presenting short-term health risks or depicting tobacco as a toxin were less effective. Conclusions Participants regarded warnings featuring proximal social risks as more salient and they were less likely to rationalise these as irrelevant. Social risk messages merit further investigation to examine their potential as a complement to traditional health warnings. PMID:23800292

  20. Impact of Waterpipe Tobacco Pack Health Warnings on Waterpipe Smoking Attitudes: A Qualitative Analysis among Regular Users in London

    PubMed Central

    Jawad, Mohammed; Bakir, Ali; Ali, Mohammed; Grant, Aimee

    2015-01-01

    Background. Despite the rise in prevalence of waterpipe tobacco smoking, it has received little legislative enforcement from governing bodies, especially in the area of health warning labels. Methods. Twenty regular waterpipe tobacco smokers from London took part in five focus groups discussing the impact of waterpipe tobacco pack health warnings on their attitudes towards waterpipe smoking. We presented them with existing and mock waterpipe tobacco products, designed to be compliant with current and future UK/EU legislation. Data were analysed using thematic analysis. Results. Participants felt packs were less attractive and health warnings were more impactful as health warnings increased in size and packaging became less branded. However, participants highlighted their lack of exposure to waterpipe tobacco pack health warnings due to the inherent nature of waterpipe smoking, that is, smoking in a café with the apparatus already prepacked by staff. Health warnings at the point of consumption had more reported impact than health warnings at the point of sale. Conclusions. Waterpipe tobacco pack health warnings are likely to be effective if compliant with existing laws and exposed to end-users. Legislations should be reviewed to extend health warning labels to waterpipe accessories, particularly the apparatus, and to waterpipe-serving premises. PMID:26273642

  1. Bringing Effective Security Warnings to Mobile Browsing Max-Emanuel Maurer

    E-print Network

    of such web pages is rated and the way it is presented to the users has changed as well. New security icons the users. Although those toolbars warned the users about phishing websites, they refused to believe them due to the professional look of the phishing site. Egelman et al. [3] tested phishing warnings

  2. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1 Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement whenever necessary or appropriate to prevent... for a cosmetic. Any such petition shall include an adequate factual basis to support the...

  3. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1 Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement whenever necessary or appropriate to prevent... for a cosmetic. Any such petition shall include an adequate factual basis to support the...

  4. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1 Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement whenever necessary or appropriate to prevent... for a cosmetic. Any such petition shall include an adequate factual basis to support the...

  5. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1 Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement whenever necessary or appropriate to prevent... for a cosmetic. Any such petition shall include an adequate factual basis to support the...

  6. 21 CFR 740.1 - Establishment of warning statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.1 Establishment of warning statements. (a) The label of a cosmetic product shall bear a warning statement whenever necessary or appropriate to prevent... for a cosmetic. Any such petition shall include an adequate factual basis to support the...

  7. The effects of hearing protectors on speech communication and the perception of warning signals

    NASA Astrophysics Data System (ADS)

    Suter, Alice H.

    1989-06-01

    Because hearing protectors attenuate the noise and signal by equal amounts within a given frequency range, reducing both to a level where there is less likelihood of distortion, they often provide improved listening conditions. The crossover level from disadvantage to advantage usually occurs between 80 and 90 dB. However, hearing protectors may adversely affect speech recognition under a variety of conditions. For hearing-impaired listeners, whose average hearing levels at 2000, 3000, and 4000 Hz exceed 30 dB, certain speech sounds will fall below the level of audibility. Visual cues may decrease the disadvantage imposed by hearing protectors. However, the Occlusion Effect, which decreases vocal output when the talker wears protection, adversely affects the listener's speech recognition. The poorest performance occurs when both talkers and listeners wear protectors. Hearing protectors affect warning signal perception in a similar manner. Again the crossover level seems to be between 80 and 90 dB, and there is greater degradation for individuals with impaired hearing. Earmuffs appear to pose greater problems than plugs, and this is especially true of difficulties in signal localization. Earplugs produce mainly front-back localization errors, while earmuffs produce left-right localization errors as well. Earmuffs also drastically impede localization in the vertical plane.

  8. 24 CFR 200.1505 - Warning letter.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...TO FHA PROGRAMS Multifamily Accelerated Processing (MAP): MAP Lender Quality Assurance Enforcement § 200.1505 Warning...specifies problems or violations identified by HUD, to a MAP lender. (b) Effect of warning letter. The...

  9. 21 CFR 201.80 - Specific requirements on content and format of labeling for human prescription drug and...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... shall state: “See ‘Warnings’ section for information on carcinogenesis, mutagenesis, and impairment of... Category D. See ‘Warnings’ section.” Under the “Warnings” section, the labeling states: “(Name of drug) can...: “Pregnancy Category X. See ‘Contraindications’ section.” Under “Contraindications,” the labeling shall...

  10. 21 CFR 201.80 - Specific requirements on content and format of labeling for human prescription drug and...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shall state: “See ‘Warnings’ section for information on carcinogenesis, mutagenesis, and impairment of... Category D. See ‘Warnings’ section.” Under the “Warnings” section, the labeling states: “(Name of drug) can...: “Pregnancy Category X. See ‘Contraindications’ section.” Under “Contraindications,” the labeling shall...

  11. 21 CFR 201.80 - Specific requirements on content and format of labeling for human prescription drug and...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... shall state: “See ‘Warnings’ section for information on carcinogenesis, mutagenesis, and impairment of... Category D. See ‘Warnings’ section.” Under the “Warnings” section, the labeling states: “(Name of drug) can...: “Pregnancy Category X. See ‘Contraindications’ section.” Under “Contraindications,” the labeling shall...

  12. 21 CFR 201.80 - Specific requirements on content and format of labeling for human prescription drug and...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... shall state: “See ‘Warnings’ section for information on carcinogenesis, mutagenesis, and impairment of... Category D. See ‘Warnings’ section.” Under the “Warnings” section, the labeling states: “(Name of drug) can...: “Pregnancy Category X. See ‘Contraindications’ section.” Under “Contraindications,” the labeling shall...

  13. 21 CFR 201.80 - Specific requirements on content and format of labeling for human prescription drug and...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... shall state: “See ‘Warnings’ section for information on carcinogenesis, mutagenesis, and impairment of... Category D. See ‘Warnings’ section.” Under the “Warnings” section, the labeling states: “(Name of drug) can...: “Pregnancy Category X. See ‘Contraindications’ section.” Under “Contraindications,” the labeling shall...

  14. A cross-sectional survey investigating the desensitisation of graphic health warning labels and their impact on smokers, non-smokers and patients with COPD in a London cohort

    PubMed Central

    Ratneswaran, Culadeeban; Chisnall, Ben; Drakatos, Panagis; Sivakumar, Sukhanthan; Sivakumar, Bairavie; Barrecheguren, Miriam; Douiri, Abdel; Steier, Joerg

    2014-01-01

    Objectives There is a lack of evidence regarding the effectiveness of graphic health warning labels (GHWL) in different individuals, including patients with chronic obstructive pulmonary disease (COPD). Investigating knowledge and attitudes may allow better implementation of future public health policies. We hypothesised that differences in the impact of GHWL exist between non-smokers, smokers and patients with COPD, with decreased efficacy in those groups who are longer and more frequently exposed to them. Participants and setting 163 participants (54% male, aged 21–80) including 60 non-smokers, 53 smokers and 50 patients with COPD (Gold stage II–IV), attending London respiratory outpatient clinics, participated in case-controlled surveys (50 items). Outcome measures Ten different GHWL were shown and demographics, smoking history, plans to quit, smoking-risk awareness, emotional response, processing and impact of GHWL on behaviour were recorded. Patients were further asked to prioritise the hypothetical treatment or prevention of five specific smoking-related diseases. Results Smokers, in particular those with COPD, were less susceptible to GHWL than non-smokers; 53.4% of all participants expressed fear when looking at GHWL, non-smokers (71.9%) more so than smokers (39.8%, p<0.001). COPD participants were less aware of the consequences than non-COPD participants (p<0.001), including an awareness of lung cancer (p=0.001). Lung cancer (95%), oral cancer (90.2%), heart disease (84.7%) and stroke (71.2%) were correctly associated with smoking, whereas blindness was least associated (23.9%). However, blindness was prioritised over oral cancer, stroke and in patients with COPD also over heart disease when participants were asked about hypothetical treatment or prevention. Conclusions GHWL are most effective in non-smokers and a desensitisation effect was observed in smokers and patients with COPD. As a consequence, a tailored and concerted public health approach to use such messages is required and ‘blindness’ deserves to be mentioned in this context because of an unexpectedly high-deterring impact. PMID:24996914

  15. The Effectiveness of Reverse Telephon Emergency Warning Systems in the October 2007 San Diego Wildfires

    SciTech Connect

    Sorensen, John H; Sorensen, Barbara Vogt

    2009-01-01

    Late in October, 2007, fast-moving wildfires fueled by extreme Santa Ana winds threatened residents and their properties in San Diego County, California. The impacted area also included the City of San Diego within the County s boundaries. It turns out the San Diego firestorms would be the biggest in the County's history, surpassing the devastating 2003 firestorms in intensity, duration, and impacted populations. Both San Diego County and the City of San Diego have installed telephone reverse call-down emergency warning systems. A telephone survey of 1200 households located in areas identified by emergency officials as the evacuation zones for the 2007 fires was conducted in late March and early April 2008 using a random telephone dialing process to determine if people responded to the reverse telephone warning systems calls. Findings indicate that those who received a reverse emergency warning call were much more likely to evacuate than those who did not receive a call. The telephone calls were also the most likely source of first warning.

  16. Driving-Simulator-Based Test on the Effectiveness of Auditory Red-Light Running Vehicle Warning System Based on Time-To-Collision Sensor

    PubMed Central

    Yan, Xuedong; Xue, Qingwan; Ma, Lu; Xu, Yongcun

    2014-01-01

    The collision avoidance warning system is an emerging technology designed to assist drivers in avoiding red-light running (RLR) collisions at intersections. The aim of this paper is to evaluate the effect of auditory warning information on collision avoidance behaviors in the RLR pre-crash scenarios and further to examine the casual relationships among the relevant factors. A driving-simulator-based experiment was designed and conducted with 50 participants. The data from the experiments were analyzed by approaches of ANOVA and structural equation modeling (SEM). The collisions avoidance related variables were measured in terms of brake reaction time (BRT), maximum deceleration and lane deviation in this study. It was found that the collision avoidance warning system can result in smaller collision rates compared to the without-warning condition and lead to shorter reaction times, larger maximum deceleration and less lane deviation. Furthermore, the SEM analysis illustrate that the audio warning information in fact has both direct and indirect effect on occurrence of collisions, and the indirect effect plays a more important role on collision avoidance than the direct effect. Essentially, the auditory warning information can assist drivers in detecting the RLR vehicles in a timely manner, thus providing drivers more adequate time and space to decelerate to avoid collisions with the conflicting vehicles. PMID:24566631

  17. Standardised (plain) cigarette packaging increases attention to both text-based and graphical health warnings: experimental evidence

    PubMed Central

    Shankleman, M.; Sykes, C.; Mandeville, K.L.; Di Costa, S.; Yarrow, K.

    2015-01-01

    Objective To investigate whether standardised cigarette packaging increases the time spent looking at health warnings, regardless of the format of those warnings. Study design A factorial (two pack styles x three warning types) within-subject experiment, with participants randomised to different orders of conditions, completed at a university in London, UK. Methods Mock-ups of cigarette packets were presented to participants with their branded portion in either standardised (plain) or manufacturer-designed (branded) format. Health warnings were present on all packets, representing all three types currently in use in the UK: black & white text, colour text, or colour images with accompanying text. Gaze position was recorded using a specialised eye tracker, providing the main outcome measure, which was the mean proportion of a five-second viewing period spent gazing at the warning-label region of the packet. Results An opportunity sample of 30 (six male, mean age = 23) young adults met the following inclusion criteria: 1) not currently a smoker; 2) <100 lifetime cigarettes smoked; 3) gaze position successfully tracked for > 50% viewing time. These participants spent a greater proportion of the available time gazing at the warning-label region when the branded section of the pack was standardised (following current Australian guidelines) rather than containing the manufacturer's preferred design (mean difference in proportions = 0.078, 95% confidence interval 0.049 to 0.106, p < 0.001). There was no evidence that this effect varied based on the type of warning label (black & white text vs. colour text vs. colour image & text; interaction p = 0.295). Conclusions During incidental viewing of cigarette packets, young adult never-smokers are likely to spend more time looking at health warnings if manufacturers are compelled to use standardised packaging, regardless of the warning design. PMID:25542740

  18. 30 CFR 47.43 - Label alternatives.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false Label alternatives. 47.43 Section 47...EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Container...Warning § 47.43 Label alternatives. The operator may...procedures, or other label alternatives for individual,...

  19. 30 CFR 47.43 - Label alternatives.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 false Label alternatives. 47.43 Section 47...EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Container...Warning § 47.43 Label alternatives. The operator may...procedures, or other label alternatives for individual,...

  20. The effects of motorcycle helmets on hearing and the detection of warning signals

    NASA Astrophysics Data System (ADS)

    Van Moorhem, W. K.; Shepherd, K. P.; Magleby, T. D.; Torian, G. E.

    1981-07-01

    Measurements of the at-ear helmet-generated aerodynamic noise and helmet insertion loss were carried out for the two major types of motorcycle helmets. From these data and existing information on noise generation by flow around a bare head it was found that for quiet motorcycles at typical operating speeds a significant part of the riders at-ear noise is generated by the air flow. An assessment of the possibility of hearing damage was then carried out. It was found that only with extremely high usage would there be a significant risk of hearing damage for either the bare headed or helmeted rider. Helmets did, however, give significant protection. Detection of warning signals was then considered. It was found that under none of the conditions investigated here did the helmet put its wearer at a disadvantage compared with the bare headed rider, and at typical constant speeds the helmet gave a rider an advantage in the detection of warning signals.

  1. Academic Warning Preclinical Y

    E-print Network

    Leistikow, Bruce N.

    warning/continue ---------------------- Fail = probation/CSP Student meets with ADSA & DOSLER --------------------- 1 Y left Student retakes exams Pass = off warning/continue ---------------------- Fail = probation ---------------------- Student retakes exams Pass = off warning/continue ---------------------- Fail = probation/CSP Student

  2. The Effects of Band Labels on Evaluators' Judgments of Musical Performance

    ERIC Educational Resources Information Center

    Silvey, Brian A.

    2009-01-01

    This study investigates the effects of band labels on evaluators' judgments of musical performance. High school concert band members (n = 72), wind ensemble members ( n = 77), and band directors (n = 8) were randomly assigned to a band label or no label group. Only the band label group was given evaluation forms that specified the group playing…

  3. Misinformation effects in eyewitness memory: the presence and absence of memory impairment as a function of warning and misinformation accessibility.

    PubMed

    Eakin, Deborah K; Schreiber, Thomas A; Sergent-Marshall, Susan

    2003-09-01

    The authors report 5 experiments investigating how exposure to misleading postevent information affects people's ability to remember details from a witnessed event. In each experiment the authors tested memory using the modified opposition test, which was designed to isolate retrieval-blocking effects. The findings indicate that retrieval blocking occurs regardless of whether the misleading information is presented before or after the witnessed event. In addition, when people are warned immediately about the presence of misleading information, they can counteract retrieval-blocking effects but only if the misinformation is relatively low in accessibility. The authors discuss the findings in terms of the retrieval-blocking hypothesis and a hypothetical suppression mechanism that can counteract retrieval-blocking effects in some circumstances. PMID:14516215

  4. Category label effects on Chinese children's inductive inferences: modulation by perceptual detail and category specificity.

    PubMed

    Long, Changquan; Lu, Xiaoying; Zhang, Li; Li, Hong; Deák, Gedeon O

    2012-02-01

    Inductive generalization of novel properties to same-category or similar-looking objects was studied in Chinese preschool children. The effects of category labels on generalizations were investigated by comparing basic-level labels, superordinate-level labels, and a control phrase applied to three kinds of stimulus materials: colored photographs (Experiment 1), realistic line drawings (Experiment 2), and cartoon-like line drawings (Experiment 3). No significant labeling effects were found for photos and realistic drawings, but there were significant effects for cartoon-like drawings. Children made mostly (>70%) category-based inferences about photographs whether or not labels were provided (Experiment 1). Children showed a bias toward category-based inferences about realistic drawings (Experiment 2) but did so only when labels were provided. Finally, children made mostly appearance-based generalizations for cartoon-like drawings (Experiment 3). However, labels (basic or superordinate level) reduced appearance-based responses. Labeling effects did not depend on having identical labels; however, identical superordinate labels were more effective than different basic-level labels for the least informative stimuli (i.e., cartoons). Thus, labels sometimes confirm the identity of ambiguous items. This evidence of labeling effects in Mandarin-speaking Chinese children extends previous findings beyond English-speaking children and shows that the effects are not narrowly culture and language specific. PMID:21945344

  5. A Study on Estimation on Flood Warning Trigger Rainfall in medium and small Stream Affected by Urban Effects

    NASA Astrophysics Data System (ADS)

    Youngseok, Song; Moojong, Park; JungHo, Lee; HeeSup, Lee

    2013-04-01

    As extreme floods occur frequently in recent years due to global climate changes, an in sudden local flooding of great volume and short duration is becoming the significant danger and loss of life and property in the Korean Peninsula as well as most parts of the world. The desire for living without hazardous damages grows these days, the city strategy to make the safer community has become an issue. Previously most of flood prevention efforts have been made for relatively large watersheds near to channel flow. However, as economical development and the expansion of city near medium and small stream, human casualty and property by flood occurs frequently. Therefore, to reduce the damage of human lives and property by flood, we develop an assessment method for flood warning trigger rainfall considering urban effect. Considering complex land use, HEC-HMS is used for rural area and SWMM is adopted for sewer networks runoff. And relationship between runoff and stream water level, HEC-RAS is accompanied with runoff results. Proposed flood warning trigger rainfall assessment method shows good agreement with gauged data and could be used for another case to mitigate damage. Acknowledgement: "This research was supported by a grant [NEMA-NH-2011-45] from the Natural Hazard Mitigation Research Group, National Emergency Management Agency of Korea." Keyword: HEC-HMS, HEC-RAS, critical precipitation, medium and small stream

  6. Effect of information education and communication (IEC) programme on knowledge of pregnant mothers regarding prevention and management of warning signs during pregnancy.

    PubMed

    Takoo, Sarla; Chhugani, Manju; Sharma, Veena

    2013-01-01

    The present study was conducted to evaluate the effectiveness of an Information, Education and Communication (IEC) programme on knowledge of pregnant mothers regarding prevention and management of warning signs during pregnancy in a selected health care setting at New Delhi. An evaluative research approach with one group pre-test and post-test design was adopted for the present study. A structured interview schedule was prepared. Purposive non-probability sampling technique was employed to interview 30 pregnant mothers who attended antenatal clinic. Data gathered was analysed and interpreted using both descriptive and inferential statistics. The study revealed that there was maximum knowledge deficit regarding warning signs of pregnancy. IEC programme was effective in enhancing the knowledge of pregnant mothers on prevention and management of warning signs during pregnancy. PMID:24974534

  7. 40 CFR 82.106 - Warning statement requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Warning statement requirements. 82.106 Section 82.106 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE The Labeling of Products Using Ozone-Depleting Substances § 82.106 Warning statement requirements....

  8. 40 CFR 82.108 - Placement of warning statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Placement of warning statement. 82.108 Section 82.108 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE The Labeling of Products Using Ozone-Depleting Substances § 82.108 Placement of warning statement....

  9. Warning systems and public warning response

    SciTech Connect

    Sorensen, J.H.

    1993-09-01

    This background paper reviews current knowledge on warning systems and human response to warnings. It expands on an earlier paper prepared for a workshop on the Second Assessment on Natural Hazards, held in Estes Park, Colorado in July 1992. Although it has a North American perspective, many of the lessons learned are universally applicable. The paper addresses warning systems in terms of dissemination and does not cover physical science issues associated with prediction and forecast. Finally, it covers hazards with relatively short lead times -- 48 hours or less. It does not address topics such as long-term forecasts of earthquakes or volcanic eruptions or early famine warning systems.

  10. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...The labeling of orally or rectally administered OTC aspirin and aspirin-containing drug products must bear a warning that...is especially important not to use” (select “aspirin” or “carbaspirin calcium,” as...

  11. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...The labeling of orally or rectally administered OTC aspirin and aspirin-containing drug products must bear a warning that...is especially important not to use” (select “aspirin” or “carbaspirin calcium,” as...

  12. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...The labeling of orally or rectally administered OTC aspirin and aspirin-containing drug products must bear a warning that...is especially important not to use” (select “aspirin” or “carbaspirin calcium,” as...

  13. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...The labeling of orally or rectally administered OTC aspirin and aspirin-containing drug products must bear a warning that...is especially important not to use” (select “aspirin” or “carbaspirin calcium,” as...

  14. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...The labeling of orally or rectally administered OTC aspirin and aspirin-containing drug products must bear a warning that...is especially important not to use” (select “aspirin” or “carbaspirin calcium,” as...

  15. Illnesses, Deaths Spur FDA Warning on Hepatitis C Drugs

    MedlinePLUS

    ... html Illnesses, Deaths Spur FDA Warning on Hepatitis C Drugs Cautionary label will be added to Viekira ... on two drugs used to fight the hepatitis C virus. The drugs, called Viekira Pak and Technivie, ...

  16. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2...section is established. (b) If the label of any cosmetic package is too small to accommodate the...

  17. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2...section is established. (b) If the label of any cosmetic package is too small to accommodate the...

  18. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2...section is established. (b) If the label of any cosmetic package is too small to accommodate the...

  19. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2...section is established. (b) If the label of any cosmetic package is too small to accommodate the...

  20. 21 CFR 740.2 - Conspicuousness of warning statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS General § 740.2...section is established. (b) If the label of any cosmetic package is too small to accommodate the...

  1. Metamnemonic Control Over the Discriminability of Memory Evidence: A Signal Detection Analysis of Warning Effects in the Associative List Paradigm

    ERIC Educational Resources Information Center

    Starns, Jeffrey J.; Lane, Sean M.; Alonzo, Jill D.; Roussel, Cristine C.

    2007-01-01

    According to signal detection theory (SDT), retrieval warnings may decrease false memory in the associative list paradigm either by inducing a conservative criterion shift or by decreasing the amount of evidence that critical theme words were studied. Fitting a SDT model to 12 existing datasets revealed suggestive evidence that warnings impact…

  2. The Effect of Labeling on Preschool Children's Performance in the Dimensional Change Card Sort Task

    ERIC Educational Resources Information Center

    Muller, Ulrich; Zelazo, Philip D.; Lurye, Leah E.; Liebermann, Dana P.

    2008-01-01

    Previous research suggests that experimenter-induced labeling of test cards improves preschoolers' performance on the Dimensional Change Card Sort Task (DCCS), a measure of flexible rule use. Three experiments attempted to further clarify how labeling aids performance on the DCCS. Experiment 1 examined the nature of the labeling effect but failed…

  3. Category Label Effects on Chinese Children's Inductive Inferences: Modulation by Perceptual Detail and Category Specificity

    ERIC Educational Resources Information Center

    Long, Changquan; Lu, Xiaoying; Zhang, Li; Li, Hong; Deak, Gedeon O.

    2012-01-01

    Inductive generalization of novel properties to same-category or similar-looking objects was studied in Chinese preschool children. The effects of category labels on generalizations were investigated by comparing basic-level labels, superordinate-level labels, and a control phrase applied to three kinds of stimulus materials: colored photographs…

  4. A more effective way to label affective expressions

    E-print Network

    Eckhardt, Micah Rye

    Labeling videos for affect content such as facial expression is tedious and time consuming. Researchers often spend significant amounts of time annotating experimental data, or simply lack the time required to label their ...

  5. Reducing online identity disclosure using warnings.

    PubMed

    Carpenter, Sandra; Zhu, Feng; Kolimi, Swapna

    2014-09-01

    In an experimental design, we tested whether written warnings can reduce the amount of identity information exposure online. A psychological attack on information privacy that has been shown to be effective in previous research was launched. This attack took advantage of the fact that people respond to certain types of requests in a relatively automatic, or mindless, fashion. The experiment manipulated the word that was used in the alert header: "warning", "caution", or "hazard". All warnings proved to be effective in reducing disclosure, but "hazard" proved to be most effective. Also warnings were more effective in reducing disclosure of driver's license numbers than email addresses. The discussion (a) provides tentative conclusions why these patterns were obtained, (b) suggests how to design warnings in cyber-environments, and (c) addresses future possibilities for research on this topic. PMID:24161300

  6. Looking at the label and beyond: the effects of calorie labels, health consciousness, and demographics on caloric intake in restaurants

    PubMed Central

    2013-01-01

    Background Recent legislation has required calorie labels on restaurant menus as a means of improving Americans’ health. Despite the growing research in this area, no consensus has been reached on the effectiveness of menu labels. This suggests the possibility of heterogeneity in responses to caloric labels across people with different attitudes and demographics. The purpose of this study was to explore the potential relationships between caloric intake and diners’ socio-economic characteristics and attitudes in a restaurant field experiment that systematically varied the caloric information printed on the menus. Methods We conducted a field experiment in a full service restaurant where patrons were randomly assigned to one of three menu treatments which varied the amount of caloric information printed on the menus (none, numeric, or symbolic calorie label). At the conclusion of their meals, diners were asked to complete a brief survey regarding their socio-economic characteristics, attitudes, and meal selections. Using regression analysis, we estimated the number of entrée and extra calories ordered by diners as a function of demographic and attitudinal variables. Additionally, irrespective of the menu treatment to which a subject was assigned, our study identified which types of people are likely to be low-, medium-, and high-calorie diners. Results Results showed that calorie labels have the greatest impact on those who are least health conscious. Additionally, using a symbolic calorie label can further reduce the caloric intake of even the most health conscious patrons. Finally, calorie labels were more likely to influence the selection of the main entrée as opposed to supplemental items such as drinks and desserts. Conclusions If numeric calorie labels are implemented (as currently proposed), they are most likely to influence consumers who are less health conscious – probably one of the key targets of this legislation. Unfortunately, numeric labels did little for those consumers who were already more knowledgeable about health and nutrition. To reach a broader group of diners, a symbolic calorie label may be preferred as it reduced caloric intake across all levels of health consciousness. PMID:23394433

  7. Multitasking in academia: Effective combinations of research, education and public outreach illustrated by a volcanic ash warning system

    NASA Astrophysics Data System (ADS)

    Bye, B. L.; Plag, H.

    2011-12-01

    Science permeates our society. Its role and its perceived importance evolves with time. Scientists today are highly specialized, yet society demands they master a variety of skills requiring not only a number of different competencies but also a broad mindset. Scientists are subjected to a meritocracy in terms of having to produce scientific papers. Peer-reviewed scientific publications used to be sufficient to meet the various laws and regulations with respect to dissemination of scientific results. This has dramatically changed; both expressed directly through public voices (such as in the climate change discourses), but also by politicians and policy makers. In some countries research funding now comes with specific requirements concerning public outreach that go way beyond peer-reviewed publications and presentation at scientific conferences. Science policies encourage multidisciplinary cooperation and scientific questions themselves often cannot be answered without knowledge and information from several scientific areas. Scientists increasingly need to communicate knowledge and results in more general terms as well as educating future generations. A huge challenge lies in developing the knowledge, human capacity and mindset that will allow an individual academician to contribute to education, communicate across scientific fields and sectors in multidisciplinary cross sectoral cooperations and also reach out to the general public while succeeding within the scientific meritocracy. We demonstrate how research, education and communication within and outside academia can effectively be combined through a presentation of the International Airways Volcano Watch that encompasses an operational volcanic ash warning system for the aviation industry. This presentation will show the role of science throughout the information flow, from basic science to the pilots' decision-making. Furthermore, it will illustrate how one can connect specific scientific topics to societal issues such as security and economy. Skills, knowledge and mindset must be developed and nurtured through university curricula and reflected in career awards and other professional appreciations. By using concrete examples of geoscience in practice, such as the volcanic ash warning system, different aspects of science, it's role in society and economic impact is being communicated across sectors and taught simultaneously. The very same information is relevant and appropriate for society at large and thus time saving for academicians. It also serves as a recruiting strategy.

  8. Pictorial Health Warnings on Cigarette Packs in the United States: An Experimental Evaluation of the Proposed FDA Warnings

    PubMed Central

    Reid, Jessica L.; Driezen, Pete; Boudreau, Christian

    2013-01-01

    Introduction: In 2010, the U.S. Food and Drug Administration (FDA) developed 36 proposed health warnings for cigarette packages, from which 9 were subsequently selected for implementation. The current study aimed to evaluate the perceived efficacy of the 36 proposed FDA warnings. Methods: Web-based surveys were conducted with 783 adult smokers and 510 youth in United States. Participants were randomized to view and rate two sets of 6–7 warnings, each set corresponding to one of nine health effect statements required under the Tobacco Control Act. Warnings included all 36 FDA-proposed warnings and additional warnings for comparison. Results: Youth and adults rated individual warnings similarly; in all cases where differences were found, youth perceived warnings as more effective. Comparisons on specific elements indicated that warnings were perceived as more effective if they were: full color (vs. black and white), featured real people (vs. comic book style), contained graphic images (vs. nongraphic), and included a telephone “quitline” number or personal information. Few sociodemographic differences were observed in overall perceived effectiveness: younger respondents, non-White respondents, and smokers intending to quit rated warnings higher. Conclusions: Seven of the nine health warnings selected by the FDA for implementation were among the proposed warnings rated as most effective in the current study. However, the warning(s) added for comparison were rated higher than the FDA-selected warning for five of the nine sets, suggesting some warnings could be improved for greater impact. The findings support the inclusion of a telephone “quitline” number and reinforce the importance of depicting “real” people and health effects. PMID:22505660

  9. 'Retouch free': The effect of labelling media images as not digitally altered on women's body dissatisfaction.

    PubMed

    Tiggemann, Marika; Slater, Amy; Smyth, Veronica

    2014-01-01

    This study aimed to investigate the effect of 'retouch free' labels on thin ideal fashion images on women's body dissatisfaction. This represents an experimental analogue to current practice by some fashion magazines. Participants were 224 female undergraduates who viewed a set of fashion shoots with either no label, or a label indicating that the image had not been digitally altered. Results indicated that, although body dissatisfaction increased after exposure to the thin ideal images, there was no significant effect of label type on mood or body dissatisfaction. It was concluded that labelling images as digitally unaltered appears neither helpful nor harmful in terms of body dissatisfaction. Nevertheless, more extensive research is required to guide the most effective use of labels. PMID:24094477

  10. Effects of safety warnings on prescription rates of cough and cold medicines in children below 2 years of age

    PubMed Central

    Sen, E Fatma; Verhamme, Katia M C; Felisi, Mariagrazia; 't Jong, Geert W; Giaquinto, Carlo; Picelli, Gino; Ceci, Adriana; Sturkenboom, Miriam C J M

    2011-01-01

    AIM The aim of the study was to assess the influence of national and international warnings on the prescription rates of cough and cold medicines (CCMs) in the youngest children (<2 years) in the Netherlands and Italy. METHODS Analysis of outpatient electronic medical records of children <2 years in Italy and the Netherlands was carried out. Age and country specific prescription prevalence rates were calculated for the period 2005–08. Comparisons of prescription rates in 2005 (pre) and 2008 (post) warnings were done by means of a chi-square test. RESULTS The cohort consisted of 99 176 children <2 years of age. After international warnings, overall prescription rates for CCMs decreased slightly from 83 to 77/1000 person years (P = 0.05) in Italy and increased in the Netherlands from 74 to 92/1000 children per year. Despite the international warnings, prescription rates for nasal sympathomimetics and opium alkaloids increased in the Netherlands (P < 0.01). In Italy a significant decrease in the prescription rates of opium alkaloids and other cough suppressants (P < 0.01) was observed, and also a significant reduction in use of combinations of nasal sympathomimetics. CONCLUSION Despite the international safety warnings and negative benefit-risk profiles, prescription rates of cough and cold medicines remain substantial and were hardly affected by the warnings, especially in the Netherlands where no warning was issued. The hazards of use of these medicines in young children should be explicitly stipulated by the European Medicines Agency and all national agencies, in order to increase awareness amongst physicians and caretakers and reduce heterogeneity across the EU. PMID:21564162

  11. Long-Term Effects of Labeling a Rape Experience

    ERIC Educational Resources Information Center

    McMullin, Darcy; White, Jacquelyn W.

    2006-01-01

    Research has found that approximately half of women who report an experience that meets the legal definition of rape do not label it rape. It has been assumed that labeling the experience as rape is necessary and beneficial for recovery; however, conflicting findings have been reported. In the present study, a longitudinal design was utilized to…

  12. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Pregnancy/breast-feeding warning. 201.63 Section...) DRUGS: GENERAL LABELING Labeling Requirements for Over-the-Counter Drugs § 201.63 Pregnancy/breast... during pregnancy or while nursing has been established for a particular drug product in a new...

  13. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Pregnancy/breast-feeding warning. 201.63 Section...) DRUGS: GENERAL LABELING Labeling Requirements for Over-the-Counter Drugs § 201.63 Pregnancy/breast... during pregnancy or while nursing has been established for a particular drug product in a new...

  14. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Pregnancy/breast-feeding warning. 201.63 Section...) DRUGS: GENERAL LABELING Labeling Requirements for Over-the-Counter Drugs § 201.63 Pregnancy/breast... during pregnancy or while nursing has been established for a particular drug product in a new...

  15. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Pregnancy/breast-feeding warning. 201.63 Section...) DRUGS: GENERAL LABELING Labeling Requirements for Over-the-Counter Drugs § 201.63 Pregnancy/breast... during pregnancy or while nursing has been established for a particular drug product in a new...

  16. 21 CFR 201.63 - Pregnancy/breast-feeding warning.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Pregnancy/breast-feeding warning. 201.63 Section...) DRUGS: GENERAL LABELING Labeling Requirements for Over-the-Counter Drugs § 201.63 Pregnancy/breast... during pregnancy or while nursing has been established for a particular drug product in a new...

  17. Quantitative Localization Microscopy: Effects of Photophysics and Labeling Stoichiometry

    PubMed Central

    Szymborska, Anna; Lidke, Keith A.; Rieger, Bernd; Stallinga, Sjoerd

    2015-01-01

    Quantification in localization microscopy with reversibly switchable fluorophores is severely hampered by the unknown number of switching cycles a fluorophore undergoes and the unknown stoichiometry of fluorophores on a marker such as an antibody. We overcome this problem by measuring the average number of localizations per fluorophore, or generally per fluorescently labeled site from the build-up of spatial image correlation during acquisition. To this end we employ a model for the interplay between the statistics of activation, bleaching, and labeling stoichiometry. We validated our method using single fluorophore labeled DNA oligomers and multiple-labeled neutravidin tetramers where we find a counting error of less than 17% without any calibration of transition rates. Furthermore, we demonstrated our quantification method on nanobody- and antibody-labeled biological specimens. PMID:25992915

  18. Application of a Tsunami Warning Message Metric to refine NOAA NWS Tsunami Warning Messages

    NASA Astrophysics Data System (ADS)

    Gregg, C. E.; Johnston, D.; Sorensen, J.; Whitmore, P.

    2013-12-01

    In 2010, the U.S. National Weather Service (NWS) funded a three year project to integrate social science into their Tsunami Program. One of three primary requirements of the grant was to make improvements to tsunami warning messages of the NWS' two Tsunami Warning Centers- the West Coast/Alaska Tsunami Warning Center (WCATWC) in Palmer, Alaska and the Pacific Tsunami Warning Center (PTWC) in Ewa Beach, Hawaii. We conducted focus group meetings with a purposive sample of local, state and Federal stakeholders and emergency managers in six states (AK, WA, OR, CA, HI and NC) and two US Territories (US Virgin Islands and American Samoa) to qualitatively asses information needs in tsunami warning messages using WCATWC tsunami messages for the March 2011 Tohoku earthquake and tsunami event. We also reviewed research literature on behavioral response to warnings to develop a tsunami warning message metric that could be used to guide revisions to tsunami warning messages of both warning centers. The message metric is divided into categories of Message Content, Style, Order and Formatting and Receiver Characteristics. A message is evaluated by cross-referencing the message with the operational definitions of metric factors. Findings are then used to guide revisions of the message until the characteristics of each factor are met. Using findings from this project and findings from a parallel NWS Warning Tiger Team study led by T. Nicolini, the WCATWC implemented the first of two phases of revisions to their warning messages in November 2012. A second phase of additional changes, which will fully implement the redesign of messages based on the metric, is in progress. The resulting messages will reflect current state-of-the-art knowledge on warning message effectiveness. Here we present the message metric; evidence-based rational for message factors; and examples of previous, existing and proposed messages.

  19. THE EFFECTS ON DRIVING SPEED OF A HEAD-UP DISPLAY OF ROAD WARNINGS (1).

    PubMed

    Huang, Cheng-Hung; Chao, Chun-Wen

    2015-10-01

    This study investigated the superimposition of the projected markings on the road with head-up display, as well as their effects on the driver's speed. Two experiments were conducted. In Exp. 1, driving operations were simulated with a desktop computer to assess 18 deceleration markings (from the factors position, shape, and color) and determined the factors and levels influencing driving speeds. Based on the results of Exp. 1, six deceleration markings (from the factors shape and color) were selected in the driving simulator for conducting Exp. 2. The results of Exp. 1 showed that markings at the sides were better than the markings in the center. In Exp. 2, there was no significant difference between the effects of the arrangement of markings and the change of shape and color on driving stability. Yellow and white colors had no significant effect on speed; however, bar markings were better than zigzag markings. The results indicated that the projection of markings on a head-up display was helpful for indicating necessary deceleration. PMID:26474437

  20. How Public Relations Professionals Can Use Food Labels as Effective Communication Tools.

    ERIC Educational Resources Information Center

    Somerick, Nancy; Weir, Lee

    1998-01-01

    Utilizes a panel of graphic arts education experts to review suggested Food and Drug Administration label guidelines--if the participants thought that "graphic problems" existed in the guidelines, they were asked to make suggestions to indicate how food labels could be prepared more effectively, at no additional cost. (PA)

  1. The Effect of Being Labelled as "Patient" on Subsequent Self-Control in Children.

    ERIC Educational Resources Information Center

    Toner, Ignatius J.; And Others

    This study investigated the effect of labeling a girl as "patient" on the girl's subsequent self-imposed delay of gratification. Subjects were 78 girls from 5 1/2 to 9 years of age. In a delay task, each child's possession of accumulating candy rewards was made contingent upon her stopping further accumulation. Labeled girls waited longer than did…

  2. The Effect of Being Labeled on Subsequent Self-Control in Children.

    ERIC Educational Resources Information Center

    Toner, Ignatius J.; And Others

    1980-01-01

    Investigates the effect of being labeled "patient" among kindergarten, first- and second-grade girls in a self-imposed delay of gratification task making rewards contingent upon stopping further accumulation. Results are interpreted in terms of modifications in the child's self perceptions as a consequence of being labeled by an adult. (RH)

  3. Effects of Labeling and Teacher Certification Type on Recall and Conflict Resolution

    ERIC Educational Resources Information Center

    Ayers, Jane M.; Krueger, Lacy E.; Jones, Beth A.

    2015-01-01

    Understanding how labels and prior training affect teachers of students with a disability is a step toward creating effective educational environments. Two goals of the present study were to examine how teacher training (special education vs. general education training) and labeling of students (either as having attention deficit hyperactivity…

  4. Effect of preparation procedures on intensity of radioautographic labeling is studied

    NASA Technical Reports Server (NTRS)

    Baserga, R.; Kisieleski, W. E.

    1967-01-01

    Effects of tissue preparation and extractive procedures on the intensity of radioautographic labeling are presented in terms of mean grain count per cell in cells labeled with tritiated precursors of proteins or nucleic acids. This information would be of interest to medical researchers and cytologists.

  5. Why People Don't Listen to Warnings: With Discussion of Implications for Futurists.

    ERIC Educational Resources Information Center

    Koster, Fran

    The document reviews recent literature on warning processes, evaluates the effectiveness of warnings in changing public policy and personal behavior, and applies warning literature to specific problem areas. Warning is interpreted to include a statement of the problem and a proposed course of action. The document is presented in six parts. Part…

  6. Effects of Labeling and Group Category of Evaluators on Evaluations of Aggression.

    PubMed

    Teraguchi, Tsukasa; Kugihara, Naoki

    2015-01-01

    This study investigated whether the effect of labeling on people's evaluation of aggression varies according to the group category of the evaluators (i.e., whether they are ingroup members or third parties). Two labeling strategies-the negative labeling of victims (NL strategy) and the positive labeling of aggressors (PL strategy)-were adopted. We conducted an experiment using the hot sauce paradigm, as a way to assess aggressive intent that includes behavioral measures of evaluations. The results suggested that the NL strategy causes ingroup members to evaluate aggression in a more positive light, while the PL strategy has the same effect but on third parties instead. Thus, labeling strategies may increase the severity of aggressors' reaction and could also be a factor that can escalate a war or conflict. PMID:26646836

  7. Effects of Labeling and Group Category of Evaluators on Evaluations of Aggression

    PubMed Central

    Teraguchi, Tsukasa; Kugihara, Naoki

    2015-01-01

    This study investigated whether the effect of labeling on people’s evaluation of aggression varies according to the group category of the evaluators (i.e., whether they are ingroup members or third parties). Two labeling strategies—the negative labeling of victims (NL strategy) and the positive labeling of aggressors (PL strategy)–were adopted. We conducted an experiment using the hot sauce paradigm, as a way to assess aggressive intent that includes behavioral measures of evaluations. The results suggested that the NL strategy causes ingroup members to evaluate aggression in a more positive light, while the PL strategy has the same effect but on third parties instead. Thus, labeling strategies may increase the severity of aggressors’ reaction and could also be a factor that can escalate a war or conflict. PMID:26646836

  8. Social Interactions Sparked by Pictorial Warnings on Cigarette Packs

    PubMed Central

    Hall, Marissa G.; Peebles, Kathryn; Bach, Laura E.; Noar, Seth M.; Ribisl, Kurt M.; Brewer, Noel T.

    2015-01-01

    The Message Impact Framework suggests that social interactions may offer smokers the opportunity to process pictorial warnings on cigarette packs more deeply. We aimed to describe adult smokers’ social interactions about pictorial cigarette pack warnings in two longitudinal pilot studies. In Pilot Study 1, 30 smokers used cigarette packs with one of nine pictorial warnings for two weeks. In Pilot Study 2, 46 smokers used cigarette packs with one of five pictorial warnings for four weeks. Nearly all smokers (97%/96% in Pilot Study 1/2) talked about the warnings with other people, with the most common people being friends (67%/87%) and spouses/significant others (34%/42%). Pilot Study 2 found that 26% of smokers talked about the warnings with strangers. Discussions about the health effects of smoking and quitting smoking were more frequent during the first week of exposure to pictorial warnings than in the week prior to beginning the study (both p < 0.05). Pictorial warnings sparked social interactions about the warnings, the health effects of smoking, and quitting smoking, indicating that pictorial warnings may act as a social intervention reaching beyond the individual. Future research should examine social interactions as a potential mediator of the impact of pictorial warnings on smoking behavior. PMID:26506363

  9. Social Interactions Sparked by Pictorial Warnings on Cigarette Packs.

    PubMed

    Hall, Marissa G; Peebles, Kathryn; Bach, Laura E; Noar, Seth M; Ribisl, Kurt M; Brewer, Noel T

    2015-10-01

    The Message Impact Framework suggests that social interactions may offer smokers the opportunity to process pictorial warnings on cigarette packs more deeply. We aimed to describe adult smokers' social interactions about pictorial cigarette pack warnings in two longitudinal pilot studies. In Pilot Study 1, 30 smokers used cigarette packs with one of nine pictorial warnings for two weeks. In Pilot Study 2, 46 smokers used cigarette packs with one of five pictorial warnings for four weeks. Nearly all smokers (97%/96% in Pilot Study 1/2) talked about the warnings with other people, with the most common people being friends (67%/87%) and spouses/significant others (34%/42%). Pilot Study 2 found that 26% of smokers talked about the warnings with strangers. Discussions about the health effects of smoking and quitting smoking were more frequent during the first week of exposure to pictorial warnings than in the week prior to beginning the study (both p < 0.05). Pictorial warnings sparked social interactions about the warnings, the health effects of smoking, and quitting smoking, indicating that pictorial warnings may act as a social intervention reaching beyond the individual. Future research should examine social interactions as a potential mediator of the impact of pictorial warnings on smoking behavior. PMID:26506363

  10. Effect of acetaminophen on the leukocyte-labeling efficiency of indium oxine In 111

    SciTech Connect

    Augustine, S.C.; Schmelter, R.F.; Nelson, K.L.; Petersen, R.J.; Qualfe, M.A.

    1983-11-01

    The effect of acetaminophen on the labeling efficiency of leukocytes with indium oxine In 111 was studied. A blood sample was obtained from eight healthy men before and after they received acetaminophen 650 mg every four hours for 24 hours. After dividing the plasma from each sample into three portions, leukocytes were separated and labeled with indium oxine In 111. In an in vitro study, 200 ml of blood was obtained from one of the men, and the plasma was separated into four portions. Acetaminophen in 95% ethanol was added to three of the plasma fractions to produce acetaminophen concentrations of 4, 20, and 100 micrograms/ml; ethanol was added to the fourth fraction as a control. Each plasma fraction was then subdivided into three aliquots, and leukocytes were labeled as in the in vivo study. Mean leukocyte labeling efficiencies in both studies were calculated from the ratios of leukocyte radioactivity to initial radioactivity in the samples, expressed as percentages. Leukocyte labeling efficiencies before acetaminophen administration ranged from 79 to 85%; after administration, labeling efficiencies ranged from 70 to 87%. No significant differences in mean labeling efficiency before and after acetaminophen administration were noted in any of the subjects. Leukocyte labeling efficiencies in all in vitro plasma fractions were reduced, ranging from 54 to 63%, but no significant differences in labeling efficiency between any of the plasma fractions were found. Using the labeling procedures in this study, exposure of leukocytes from healthy men to acetaminophen in vivo or in vitro does not affect labeling efficiency with indium oxine In 111.

  11. The effects of nutrition labeling on consumer food choice: a psychological experiment and computational model.

    PubMed

    Helfer, Peter; Shultz, Thomas R

    2014-12-01

    The widespread availability of calorie-dense food is believed to be a contributing cause of an epidemic of obesity and associated diseases throughout the world. One possible countermeasure is to empower consumers to make healthier food choices with useful nutrition labeling. An important part of this endeavor is to determine the usability of existing and proposed labeling schemes. Here, we report an experiment on how four different labeling schemes affect the speed and nutritional value of food choices. We then apply decision field theory, a leading computational model of human decision making, to simulate the experimental results. The psychology experiment shows that quantitative, single-attribute labeling schemes have greater usability than multiattribute and binary ones, and that they remain effective under moderate time pressure. The computational model simulates these psychological results and provides explanatory insights into them. This work shows how experimental psychology and computational modeling can contribute to the evaluation and improvement of nutrition-labeling schemes. PMID:24913496

  12. The Effects of Symptom Recognition and Diagnostic Labels on Public Beliefs, Emotional Reactions, and Stigmas Associated with Intellectual Disability

    ERIC Educational Resources Information Center

    Scior, Katrina; Connolly, Theresa; Williams, Janice

    2013-01-01

    Labels are firmly rejected by the disability rights movement, yet the complex effects of labeling on lay beliefs are poorly understood. This study examined the effects of labeling on the general public's reactions to people with intellectual disabilities. A sample of 1,233 adult members of the UK general population were randomly presented with…

  13. 19 CFR 122.115 - Labeling of cargo.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AIR COMMERCE REGULATIONS Transit Air Cargo Manifest (TACM) Procedures § 122.115 Labeling of cargo. A warning label, as required by § 18.4(e) of this chapter, shall be attached to all transit air cargo...

  14. Red blood cell labeling with technetium-99m. Effect of radiopaque contrast agents

    SciTech Connect

    Finkel, J.; Chervu, L.R.; Bernstein, R.G.; Srivastava, S.C.

    1988-03-01

    Radiographic contrast agents have been reported in the literature to interfere significantly with red blood cell (RBC) labeling in vivo by Tc-99m. Moreover, in the presence of contrast agents, red cells have been known to undergo significant morphologic changes. These observations led to the current RBC labeling study in patients (N = 25) undergoing procedures with the administration of contrast media. Before and after contrast administration, blood samples were drawn from each patient into vacutainer tubes containing heparin and RBC labeling was performed using 1-ml aliquots of these samples following the Brookhaven National Laboratory protocol. The differences in average percentage labeling yield with and without contrast media were not significant. In vivo labeling in hypertensive rats with administration of contrast media up to 600 mg likewise consistently gave high labeling yields at all concentrations. Purported alterations in cell labeling attributed to contrast agents are not reflected in these studies, and other pathophysiologic factors need to be identified to substantiate the previous reports. In vitro study offers a potentially useful and simple method to delineate effects of various agents on cell labeling.

  15. Communication of emergency public warnings: A social science perspective and state-of-the-art assessment

    SciTech Connect

    Mileti, D.S. ); Sorensen, J.H. )

    1990-08-01

    More than 200 studies of warning systems and warning response were reviewed for this social science perspective and state-of-the-art assessment of communication of emergency public warnings. The major findings are as follows. First, variations in the nature and content of warnings have a large impact on whether or not the public heeds the warning. Relevant factors include the warning source; warning channel; the consistency, credibility, accuracy, and understandability of the message; and the warning frequency. Second, characteristics of the population receiving the warning affect warning response. These include social characteristics such as gender, ethnicity and age, social setting characteristics such as stage of life or family context, psychological characteristics such as fatalism or risk perception, and knowledge characteristics such as experience or training. Third, many current myths about public response to emergency warning are at odds with knowledge derived from field investigations. Some of these myths include the keep it simple'' notion, the cry wolf'' syndrome, public panic and hysteria, and those concerning public willingness to respond to warnings. Finally, different methods of warning the public are not equally effective at providing an alert and notification in different physical and social settings. Most systems can provide a warning given three or more hours of available warning time. Special systems such as tone-alert radios are needed to provide rapid warning. 235 refs., 8 figs., 2 tabs.

  16. 30 CFR 47.42 - Label contents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Label contents. 47.42 Section 47.42 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Container Labels and Other Forms of Warning § 47.42 Label contents. When an operator...

  17. 30 CFR 47.42 - Label contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Label contents. 47.42 Section 47.42 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Container Labels and Other Forms of Warning § 47.42 Label contents. When an operator...

  18. 30 CFR 47.42 - Label contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Label contents. 47.42 Section 47.42 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Container Labels and Other Forms of Warning § 47.42 Label contents. When an operator...

  19. 30 CFR 47.42 - Label contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Label contents. 47.42 Section 47.42 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Container Labels and Other Forms of Warning § 47.42 Label contents. When an operator...

  20. 30 CFR 47.42 - Label contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Label contents. 47.42 Section 47.42 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING HAZARD COMMUNICATION (HazCom) Container Labels and Other Forms of Warning § 47.42 Label contents. When an operator...

  1. Effect of Superparamagnetic Iron Oxide Nanoparticles-Labeling on Mouse Embryonic Stem Cells

    PubMed Central

    Parsa, Hamed; Shamsasenjan, Karim; Movassaghpour, Aliakbar; Akbarzadeh, Parvin; Amoghli Tabrizi, Bahram; Dehdilani, Nima; Lotfinegad, Parisa; Soleimanloo, Farzaneh

    2015-01-01

    Objective Superparamagnetic iron oxide nanoparticles (SPIONs) have been used to label mammalian cells and to monitor their fate in vivo using magnetic resonance imaging (MRI). However, the effectiveness of phenotype of labeled cells by SPIONs is still a matter of question. The aim of this study was to investigate the efficiency and biological effects of labeled mouse embryonic stem cells (mESCs) using ferumoxide- protamine sulfate complex. Materials and Methods In an experimental study, undifferentiated mESCs, C571 line, a generous gift of Stem Cell Technology Company, were cultured on gelatin-coated flasks. The proliferation and viability of SPION-labeled cells were compared with control. ESCs and embryoid bodies (EBs) derived from differentiated hematopoietic stem cells (HSCs) were analyzed for stage-specific cell surface markers using fluorescence-activated cell sorting (FACS). Results Our observations showed that SPIONs have no effect on the self-renewal ability of mESCs. Reverse microscopic observations and prussian blue staining revealed 100% of cells were labeled with iron particles. SPION-labeled mESCs did not significantly alter cell viability and proliferation activity. Furthermore, labeling did not alter expression of representative surface phenotypic markers such as stage-specific embryonic antigen 1 (SSEA1) and cluster of differentiation 117 (CD117) on undifferentiated ESC and CD34, CD38 on HSCs, as measured by flowcytometry. Conclusion According to the results of the present study, SPIONs-labeling method as MRI agents in mESCs has no negative effects on growth, morphology, viability, proliferation and differentiation that can be monitored in vivo, noninvasively. Noninvasive cell tracking methods are considered as new perspectives in cell therapy for clinical use and as an easy method for evaluating the placement of stem cells after transplantation. PMID:26199901

  2. Evolution of tsunami warning systems and products

    PubMed Central

    Bernard, Eddie; Titov, Vasily

    2015-01-01

    Each year, about 60?000 people and $4 billion (US$) in assets are exposed to the global tsunami hazard. Accurate and reliable tsunami warning systems have been shown to provide a significant defence for this flooding hazard. However, the evolution of warning systems has been influenced by two processes: deadly tsunamis and available technology. In this paper, we explore the evolution of science and technology used in tsunami warning systems, the evolution of their products using warning technologies, and offer suggestions for a new generation of warning products, aimed at the flooding nature of the hazard, to reduce future tsunami impacts on society. We conclude that coastal communities would be well served by receiving three standardized, accurate, real-time tsunami warning products, namely (i) tsunami energy estimate, (ii) flooding maps and (iii) tsunami-induced harbour current maps to minimize the impact of tsunamis. Such information would arm communities with vital flooding guidance for evacuations and port operations. The advantage of global standardized flooding products delivered in a common format is efficiency and accuracy, which leads to effectiveness in promoting tsunami resilience at the community level. PMID:26392620

  3. Evolution of tsunami warning systems and products.

    PubMed

    Bernard, Eddie; Titov, Vasily

    2015-10-28

    Each year, about 60?000 people and $4 billion (US$) in assets are exposed to the global tsunami hazard. Accurate and reliable tsunami warning systems have been shown to provide a significant defence for this flooding hazard. However, the evolution of warning systems has been influenced by two processes: deadly tsunamis and available technology. In this paper, we explore the evolution of science and technology used in tsunami warning systems, the evolution of their products using warning technologies, and offer suggestions for a new generation of warning products, aimed at the flooding nature of the hazard, to reduce future tsunami impacts on society. We conclude that coastal communities would be well served by receiving three standardized, accurate, real-time tsunami warning products, namely (i) tsunami energy estimate, (ii) flooding maps and (iii) tsunami-induced harbour current maps to minimize the impact of tsunamis. Such information would arm communities with vital flooding guidance for evacuations and port operations. The advantage of global standardized flooding products delivered in a common format is efficiency and accuracy, which leads to effectiveness in promoting tsunami resilience at the community level. PMID:26392620

  4. 75 FR 75936 - Required Warnings for Cigarette Packages and Advertisements; Research Report

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ...The Food and Drug Administration (FDA) is announcing that it has added a document to the docket for the proposed rulemaking concerning required textual warnings and accompanying graphics to be displayed on cigarette packages and in cigarette advertisements. The document is a report entitled ``Report: Experimental Study of Graphic Cigarette Warning Labels'' (Experimental Study Report) and it......

  5. Effect of labeling on new vegetable dish acceptance in preadolescent children.

    PubMed

    Morizet, David; Depezay, Laurence; Combris, Pierre; Picard, Delphine; Giboreau, Agnès

    2012-10-01

    The aim of this study was to explore the effectiveness of a food-labeling strategy to introduce new versions of foods to children's diets, in natural lunch settings (school canteens). The proposed food involved two different types of vegetables: carrots (very familiar) and broccoli (less familiar), both being prepared and presented for choice in a 'familiar' (known) versus a 'new' (unknown) version. We assessed whether adding a label (either basic or model-related) to new versions of vegetable dishes would increase the likelihood that 8- to 11-year-old children would select the new dishes rather than the familiar versions. In the first condition (no label/control condition), both the familiar and the new versions of the vegetable dishes were presented with absence of any information. In the second condition (basic label condition), the new dish was presented accompanied by a basic label: "new carrot/broccoli recipe". In the third condition (model-related label condition), the new version of the dish was presented with a model-related label: "new carrot/broccoli recipe, Special Mix for Super Heroes". Results showed that children chose significantly more often the familiar version of the dish when no information was given (control condition). The addition of a descriptive label (whether basic or model-related) led to an increased frequency of choice for the new vegetable dish for carrots only, and not for broccoli. This study suggests that adding a label with the vegetable's name can be used to increase children's willingness to select a new version of a vegetable dish instead of a familiar one, at least when the vegetable is familiar to the children (i.e. carrots). PMID:22664298

  6. 42 CFR 84.257 - Labeling requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Special Use Respirators § 84.257 Labeling requirements. (a) A warning shall...

  7. 27 CFR 20.134 - Labeling.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...to the proof strength, and (iv) shall have the warning “For external use only. If taken internally, will cause serious gastric disturbances.” An alcohol rub made from any other material, such as isopropyl alcohol, shall not be labeled “Rubbing...

  8. 21 CFR 660.45 - Labeling.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B Surface Antigen § 660.45 Labeling...the product is capable of transmitting hepatitis and should be handled accordingly...warnings as to possible hazards, including hepatitis transmitted in handling the product...

  9. 21 CFR 660.45 - Labeling.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B Surface Antigen § 660.45 Labeling...the product is capable of transmitting hepatitis and should be handled accordingly...warnings as to possible hazards, including hepatitis transmitted in handling the product...

  10. 21 CFR 660.45 - Labeling.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B Surface Antigen § 660.45 Labeling...the product is capable of transmitting hepatitis and should be handled accordingly...warnings as to possible hazards, including hepatitis transmitted in handling the product...

  11. 21 CFR 660.45 - Labeling.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B Surface Antigen § 660.45 Labeling...the product is capable of transmitting hepatitis and should be handled accordingly...warnings as to possible hazards, including hepatitis transmitted in handling the product...

  12. 21 CFR 660.45 - Labeling.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Hepatitis B Surface Antigen § 660.45 Labeling...the product is capable of transmitting hepatitis and should be handled accordingly...warnings as to possible hazards, including hepatitis transmitted in handling the product...

  13. 75 FR 50770 - Guidance for Industry on Organ-Specific Warnings: Internal Analgesic, Antipyretic, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ...anti-inflammatory drug ingredients (NSAIDs). The labeling of those products must include specific warnings about the risks of liver injury when using acetaminophen, and stomach bleeding when using nonsteroidal NSAIDs, as well as related information...

  14. Can words heal? Using affect labeling to reduce the effects of unpleasant cues on symptom reporting

    PubMed Central

    Constantinou, Elena; Van Den Houte, Maaike; Bogaerts, Katleen; Van Diest, Ilse; Van den Bergh, Omer

    2014-01-01

    Processing unpleasant affective cues induces elevated momentary symptom reports, especially in persons with high levels of symptom reporting in daily life. The present study aimed to examine whether applying an emotion regulation strategy, i.e. affect labeling, can inhibit these emotion influences on symptom reporting. Student participants (N = 61) with varying levels of habitual symptom reporting completed six picture viewing trials of homogeneous valence (three pleasant, three unpleasant) under three conditions: merely viewing, emotional labeling, or content (non-emotional) labeling. Affect ratings and symptom reports were collected after each trial. Participants completed a motor inhibition task and self-control questionnaires as indices of their inhibitory capacities. Heart rate variability was also measured. Labeling, either emotional or non-emotional, significantly reduced experienced affect, as well as the elevated symptoms reports observed after unpleasant picture viewing. These labeling effects became more pronounced with increasing levels of habitual symptom reporting, suggesting a moderating role of the latter variable, but did not correlate with any index of general inhibitory capacity. Our findings suggest that using an emotion regulation strategy, such as labeling emotional stimuli, can reverse the effects of unpleasant stimuli on symptom reporting and that such strategies can be especially beneficial for individuals suffering from medically unexplained physical symptoms. PMID:25101048

  15. Desired and Undesired Effects of Energy Labels—An Eye-Tracking Study

    PubMed Central

    Waechter, Signe; Sütterlin, Bernadette; Siegrist, Michael

    2015-01-01

    Saving energy is an important pillar for the mitigation of climate change. Electric devices (e.g., freezer and television) are an important player in the residential sector in the final demand for energy. Consumers’ purchase decisions are therefore crucial to successfully reach the energy-efficiency goals. Putting energy labels on products is often considered an adequate way of empowering consumers to make informed purchase decisions. Consequently, this approach should contribute to reducing overall energy consumption. The effectiveness of its measurement depends on consumers’ use and interpretation of the information provided. Despite advances in energy efficiency and a mandatory labeling policy, final energy consumption per capita is in many countries still increasing. This paper provides a systematic analysis of consumers’ reactions to one of the most widely used eco-labels, the European Union (EU) energy label, by using eye-tracking methodology as an objective measurement. The study’s results partially support the EU’s mandatory policy, showing that the energy label triggers attention toward energy information in general. However, the energy label’s effect on consumers’ actual product choices seems to be rather low. The study’s results show that the currently used presentation format on the label is insufficient. The findings suggest that it does not facilitate the integration of energy-related information. Furthermore, the current format can attract consumers to focus more on energy-efficiency information, leading them to disregard information about actual energy consumption. As a result, the final energy consumption may increase because excellent ratings on energy efficiency (e.g., A++) do not automatically imply little consumption. Finally, implications for policymakers and suggestions for further research are discussed. PMID:26231028

  16. Disaster warning satellite study

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The Disaster Warning Satellite System is described. It will provide NOAA with an independent, mass communication system for the purpose of warning the public of impending disaster and issuing bulletins for corrective action to protect lives and property. The system consists of three major segments. The first segment is the network of state or regional offices that communicate with the central ground station; the second segment is the satellite that relays information from ground stations to home receivers; the third segment is composed of the home receivers that receive information from the satellite and provide an audio output to the public. The ground stations required in this system are linked together by two, separate, voice bandwidth communication channels on the Disaster Warning Satellites so that a communications link would be available in the event of disruption of land line service.

  17. GEO Label - Quality Information Interrogation Tool for Geospatial Datasets: Towards Effective Visualization of Quality Metadata.

    NASA Astrophysics Data System (ADS)

    Lush, Victoria; Lumsden, Jo; Bastin, Lucy

    2013-04-01

    Although the importance of dataset fitness-for-use evaluation and intercomparison is widely recognised within the GIS community, no practical tools have yet been developed to support such interrogation. GeoViQua aims to develop a GEO label which will visually summarise and allow interrogation of key informational aspects of geospatial datasets upon which users rely when selecting datasets for use. The proposed GEO label will be integrated in the Global Earth Observation System of Systems (GEOSS) and will be used as a value and trust indicator for datasets accessible through the GEO Portal. As envisioned, the GEO label will act as a decision support mechanism for dataset selection and thereby hopefully improve user recognition of the quality of datasets. To date we have conducted 3 user studies to (1) identify the informational aspects of geospatial datasets upon which users rely when assessing dataset quality and trustworthiness, (2) elicit initial user views on a GEO label and its potential role and (3), evaluate prototype label visualisations. Our first study revealed that, when evaluating quality of data, users consider 8 facets: dataset producer information; producer comments on dataset quality; dataset compliance with international standards; community advice; dataset ratings; links to dataset citations; expert value judgements; and quantitative quality information. Our second study confirmed the relevance of these facets in terms of the community-perceived function that a GEO label should fulfil: users and producers of geospatial data supported the concept of a GEO label that provides a drill-down interrogation facility covering all 8 informational aspects. Consequently, we developed three prototype label visualisations and evaluated their comparative effectiveness and user preference via a third user study to arrive at a final graphical GEO label representation. When integrated in the GEOSS, an individual GEO label will be provided for each dataset in the GEOSS clearinghouse (or other data portals and clearinghouses) based on its available quality information. Producer and feedback metadata documents are being used to dynamically assess information availability and generate the GEO labels. The producer metadata document can either be a standard ISO compliant metadata record supplied with the dataset, or an extended version of a GeoViQua-derived metadata record, and is used to assess the availability of a producer profile, producer comments, compliance with standards, citations and quantitative quality information. GeoViQua is also currently developing a feedback server to collect and encode (as metadata records) user and producer feedback on datasets; these metadata records will be used to assess the availability of user comments, ratings, expert reviews and user-supplied citations for a dataset. The GEO label will provide drill-down functionality which will allow a user to navigate to a GEO label page offering detailed quality information for its associated dataset. At this stage, we are developing the GEO label service that will be used to provide GEO labels on demand based on supplied metadata records. In this presentation, we will provide a comprehensive overview of the GEO label development process, with specific emphasis on the GEO label implementation and integration into the GEOSS.

  18. A "Nutrition Label" for Privacy Patrick Gage Kelley,*

    E-print Network

    Sadeh, Norman M.

    A "Nutrition Label" for Privacy Patrick Gage Kelley,* Joanna Bresee,* Lorrie Faith Cranor,* Robert presentation and comprehensibility of privacy policies. Drawing from nutrition, warning, and energy labeling Keywords privacy, P3P, policy, user interface, information design, labeling, nutrition label. 1

  19. 40 CFR 156.66 - Child hazard warning.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must...

  20. 40 CFR 156.66 - Child hazard warning.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must...

  1. 40 CFR 156.66 - Child hazard warning.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must...

  2. 40 CFR 156.66 - Child hazard warning.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must...

  3. 40 CFR 156.66 - Child hazard warning.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Child hazard warning. 156.66 Section... LABELING REQUIREMENTS FOR PESTICIDES AND DEVICES Human Hazard and Precautionary Statements § 156.66 Child... Out of Reach of Children.” That statement, or any alternative statement approved by EPA, must...

  4. Effectiveness of Front-Of-Pack Nutrition Labels in French Adults: Results from the NutriNet-Santé Cohort Study

    PubMed Central

    Ducrot, Pauline; Méjean, Caroline; Julia, Chantal; Kesse-Guyot, Emmanuelle; Touvier, Mathilde; Fezeu, Léopold; Hercberg, Serge; Péneau, Sandrine

    2015-01-01

    Background To date, no consensus has emerged on the most appropriate front-of-pack (FOP) nutrition label to help consumers in making informed choices. We aimed to compare the effectiveness of the label formats currently in use: nutrient-specific, graded and simple summary systems, in a large sample of adults. Methods The FOP label effectiveness was assessed by measuring the label acceptability and understanding among 13,578 participants of the NutriNet-Santé cohort study, representative of the French adult population. Participants were exposed to five conditions, including four FOP labels: Guideline Daily Amounts (GDA), Multiple Traffic Lights (MTL), 5-Color Nutrition Label (5-CNL), Green Tick (Tick), and a “no label” condition. Acceptability was evaluated by several indicators: attractiveness, liking and perceived cognitive workload. Objective understanding was assessed by the percentage of correct answers when ranking three products according to their nutritional quality. Five different product categories were tested: prepared fish dishes, pizzas, dairy products, breakfast cereals, and appetizers. Differences among the label effectiveness were compared with chi-square tests. Results The 5-CNL was viewed as the easiest label to identify and as the one requiring the lowest amount of effort and time to understand. GDA was considered as the least easy to identify and to understand, despite being the most attractive and liked label. All FOP labels were found to be effective in ranking products according to their nutritional quality compared with the “no label” situation, although they showed differing levels of effectiveness (p<0.0001). Globally, the 5-CNL performed best, followed by MTL, GDA and Tick labels. Conclusions The graded 5-CNL label was considered as easy to identify, simple and rapid to understand; it performed well when comparing the products’ nutritional quality. Therefore, it is likely to present advantages in real shopping situations where choices are usually made quickly. PMID:26509679

  5. Modeling warning times for the Israel's earthquake early warning system

    NASA Astrophysics Data System (ADS)

    Pinsky, Vladimir

    2015-01-01

    In June 2012, the Israeli government approved the offer of the creation of an earthquake early warning system (EEWS) that would provide timely alarms for schools and colleges in Israel. A network configuration was chosen, consisting of a staggered line of ˜100 stations along the main regional faults: the Dead Sea fault and the Carmel fault, and an additional ˜40 stations spread more or less evenly over the country. A hybrid approach to the EEWS alarm was suggested, where a P-wave-based system will be combined with the S-threshold method. The former utilizes first arrivals to several stations closest to the event for prompt location and determination of the earthquake's magnitude from the first 3 s of the waveform data. The latter issues alarms, when the acceleration of the surface movement exceeds a threshold for at least two neighboring stations. The threshold will be chosen to be a peak acceleration level corresponding to a magnitude 5 earthquake at a short distance range (5-10 km). The warning times or lead times, i.e., times between the alarm signal arrival and arrival of the damaging S-waves, are considered for the P, S, and hybrid EEWS methods. For each of the approaches, the P- and the S-wave travel times and the alarm times were calculated using a standard 1D velocity model and some assumptions regarding the EEWS data latencies. Then, a definition of alarm effectiveness was introduced as a measure of the trade-off between the warning time and the shaking intensity. A number of strong earthquake scenarios, together with anticipated shaking intensities at important targets, namely cities with high populations, are considered. The scenarios demonstrated in probabilistic terms how the alarm effectiveness varies depending on the target distance from the epicenter and event magnitude.

  6. Modeling warning times for the Israel's earthquake early warning system

    NASA Astrophysics Data System (ADS)

    Pinsky, Vladimir

    2014-09-01

    In June 2012, the Israeli government approved the offer of the creation of an earthquake early warning system (EEWS) that would provide timely alarms for schools and colleges in Israel. A network configuration was chosen, consisting of a staggered line of ˜100 stations along the main regional faults: the Dead Sea fault and the Carmel fault, and an additional ˜40 stations spread more or less evenly over the country. A hybrid approach to the EEWS alarm was suggested, where a P-wave-based system will be combined with the S-threshold method. The former utilizes first arrivals to several stations closest to the event for prompt location and determination of the earthquake's magnitude from the first 3 s of the waveform data. The latter issues alarms, when the acceleration of the surface movement exceeds a threshold for at least two neighboring stations. The threshold will be chosen to be a peak acceleration level corresponding to a magnitude 5 earthquake at a short distance range (5-10 km). The warning times or lead times, i.e., times between the alarm signal arrival and arrival of the damaging S-waves, are considered for the P, S, and hybrid EEWS methods. For each of the approaches, the P- and the S-wave travel times and the alarm times were calculated using a standard 1D velocity model and some assumptions regarding the EEWS data latencies. Then, a definition of alarm effectiveness was introduced as a measure of the trade-off between the warning time and the shaking intensity. A number of strong earthquake scenarios, together with anticipated shaking intensities at important targets, namely cities with high populations, are considered. The scenarios demonstrated in probabilistic terms how the alarm effectiveness varies depending on the target distance from the epicenter and event magnitude.

  7. GEO Label Web Services for Dynamic and Effective Communication of Geospatial Metadata Quality

    NASA Astrophysics Data System (ADS)

    Lush, Victoria; Nüst, Daniel; Bastin, Lucy; Masó, Joan; Lumsden, Jo

    2014-05-01

    We present demonstrations of the GEO label Web services and their integration into a prototype extension of the GEOSS portal (http://scgeoviqua.sapienzaconsulting.com/web/guest/geo_home), the GMU portal (http://gis.csiss.gmu.edu/GADMFS/) and a GeoNetwork catalog application (http://uncertdata.aston.ac.uk:8080/geonetwork/srv/eng/main.home). The GEO label is designed to communicate, and facilitate interrogation of, geospatial quality information with a view to supporting efficient and effective dataset selection on the basis of quality, trustworthiness and fitness for use. The GEO label which we propose was developed and evaluated according to a user-centred design (UCD) approach in order to maximise the likelihood of user acceptance once deployed. The resulting label is dynamically generated from producer metadata in ISO or FDGC format, and incorporates user feedback on dataset usage, ratings and discovered issues, in order to supply a highly informative summary of metadata completeness and quality. The label was easily incorporated into a community portal as part of the GEO Architecture Implementation Programme (AIP-6) and has been successfully integrated into a prototype extension of the GEOSS portal, as well as the popular metadata catalog and editor, GeoNetwork. The design of the GEO label was based on 4 user studies conducted to: (1) elicit initial user requirements; (2) investigate initial user views on the concept of a GEO label and its potential role; (3) evaluate prototype label visualizations; and (4) evaluate and validate physical GEO label prototypes. The results of these studies indicated that users and producers support the concept of a label with drill-down interrogation facility, combining eight geospatial data informational aspects, namely: producer profile, producer comments, lineage information, standards compliance, quality information, user feedback, expert reviews, and citations information. These are delivered as eight facets of a wheel-like label, which are coloured according to metadata availability and are clickable to allow a user to engage with the original metadata and explore specific aspects in more detail. To support this graphical representation and allow for wider deployment architectures we have implemented two Web services, a PHP and a Java implementation, that generate GEO label representations by combining producer metadata (from standard catalogues or other published locations) with structured user feedback. Both services accept encoded URLs of publicly available metadata documents or metadata XML files as HTTP POST and GET requests and apply XPath and XSLT mappings to transform producer and feedback XML documents into clickable SVG GEO label representations. The label and services are underpinned by two XML-based quality models. The first is a producer model that extends ISO 19115 and 19157 to allow fuller citation of reference data, presentation of pixel- and dataset- level statistical quality information, and encoding of 'traceability' information on the lineage of an actual quality assessment. The second is a user quality model (realised as a feedback server and client) which allows reporting and query of ratings, usage reports, citations, comments and other domain knowledge. Both services are Open Source and are available on GitHub at https://github.com/lushv/geolabel-service and https://github.com/52North/GEO-label-java. The functionality of these services can be tested using our GEO label generation demos, available online at http://www.geolabel.net/demo.html and http://geoviqua.dev.52north.org/glbservice/index.jsf.

  8. earthquake warning earthquake strikes

    E-print Network

    Emergency earthquake warning When an earthquake strikes Immediately after the earthquake Several-8550 For Students LargeLaargege Earthquake #12;According to tables explaining the JMA (Japan Meteorological Agency situation Wooden houses Ground situation Lifelines Slopes, etc. situation In preparation for an earthquake

  9. earthquake warning earthquake strikes

    E-print Network

    Emergency earthquake warning When an earthquake strikes Immediately after the earthquake Several, Kanagawa 226-8503 For Students LargeLaargege Earthquake #12;According to tables explaining the JMA (Japan for an earthquake with a seismic intensity of 5-Lower or greater, this manual summarizes what you should do

  10. Stannous glucoheptonate: An effective tinning agent for Tc-99m labeling of blood cells

    SciTech Connect

    Straub, R.F.; Meinken, G.E.; Srivastava, S.C.

    1986-01-01

    Of the various tin compounds studied, stannous glucoheptonate proved to be the most effective tinning agent for labelling blood cells with technetium 99. Much less tin was needed to achieve a rapid and satisfactory intracellular Sn(II) content. Less Sn(II) remained extracellular, facilitating its removal by oxidation or washing. Highest /sup 99m/Tc-labeling efficiencies are obtained for RBC, leukocytes, and platelets. Label stability in vitro was higher (2 to 3% washout from /sup 99m/Tc-RBC, and approx. 10% from /sup 99m/Tc-leukocytes and platelets, upon prolonged incubation with saline or plasma). The order of effectiveness for the tinning agents tested is glucoheptonate > citrate >> DTPA > PYP. 4 refs., 6 figs.

  11. Tsunami early warning using earthquake rupture duration Anthony Lomax1

    E-print Network

    Rawlinson, Nick

    Tsunami early warning using earthquake rupture duration Anthony Lomax1 and Alberto Michelini2] Effective tsunami early warning for coastlines near a tsunamigenic earthquake requires notification within 5, greater than about 50 s. Here we show that T0 gives more information on tsunami importance than moment

  12. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...2014-04-01 2014-04-01 false Labeling of cosmetic products for which adequate substantiation of safety...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements...

  13. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...2013-04-01 2013-04-01 false Labeling of cosmetic products for which adequate substantiation of safety...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements...

  14. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...2012-04-01 2012-04-01 false Labeling of cosmetic products for which adequate substantiation of safety...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements...

  15. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...2011-04-01 2010-04-01 true Labeling of cosmetic products for which adequate substantiation of safety...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements...

  16. Effects of Picture Labeling on Science Text Processing and Learning: Evidence from Eye Movements

    ERIC Educational Resources Information Center

    Mason, Lucia; Pluchino, Patrik; Tornatora, Maria Caterina

    2013-01-01

    This study investigated the effects of reading a science text illustrated by either a labeled or unlabeled picture. Both the online process of reading the text and the offline conceptual learning from the text were examined. Eye-tracking methodology was used to trace text and picture processing through indexes of first- and second-pass reading or…

  17. 77 FR 72868 - Compliance Guidance for Small Business Entities on Labeling and Effectiveness Testing; Sunscreen...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... (76 FR 35620) regarding labeling and testing requirements for OTC sunscreen drug products. Under the... From the Federal Register Online via the Government Printing Office DEPARTMENT OF HEALTH AND HUMAN... Effectiveness Testing; Sunscreen Drug Products for Over-the-Counter Human Use; Notice of Availability...

  18. The Effects of Child Age and Label on Instructor Expectation and Performance.

    ERIC Educational Resources Information Center

    Toner, Ignatius J.; Hagan, Margaret S.

    The present study explored the dynamics of expectancy effects. The process by which labels about children provided to adults (but not to the children themselves) achieve their outcomes was investigated. Forty-eight undergraduate females were provided with information about children whom they were to instruct; each undergraduate was then…

  19. The Effects of Verbal Labels and Vocabulary Skill on Memory and Suggestibility

    ERIC Educational Resources Information Center

    Kulkofsky, Sarah

    2010-01-01

    The current study investigated the effectiveness of the verbal labels procedure (D. A. Brown & M. E. Pipe, 2003) to improve preschool children's responses to direct open-ended and misleading questions. Additionally, children's vocabulary skill was considered. Eighty-seven preschool children from diverse backgrounds were interviewed about a unique…

  20. Effective Graph Classification Based on Topological and Label Attributes , Murat Semerci2

    E-print Network

    Zaki, Mohammed Javeed

    online 12 June 2012 in Wiley Online Library (wileyonlinelibrary.com). Abstract: Graph classificationEffective Graph Classification Based on Topological and Label Attributes Geng Li1 , Murat Semerci2 propose an alternative approach to graph classification that is based on feature vectors constructed from

  1. Effects of Labeling on Preschoolers' Explicit False Belief Performance: Outcomes of Cognitive Flexibility or Inhibitory Control?

    ERIC Educational Resources Information Center

    Low, Jason; Simpson, Samantha

    2012-01-01

    Executive function mechanisms underpinning language-related effects on theory of mind understanding were examined in a sample of 165 preschoolers. Verbal labels were manipulated to identify relevant perspectives on an explicit false belief task. In Experiment 1 with 4-year-olds (N = 74), false belief reasoning was superior in the fully and…

  2. Attitudes Toward Retarded Children: Effects of Labeling and Behavioral Aggressiveness. Volume 4, Number 74.

    ERIC Educational Resources Information Center

    Gottlieb, Jay

    Effects of the label "mentally retarded" on attitudes of peers were examined among 48 third grade pupils. Half of the Ss were shown a videotape of an actor displaying acting out behavior, while the remaining Ss were shown a videotape with the same actor engaging in passive behavior. Half of the Ss in each group were told that the actor was a…

  3. 76 FR 30093 - Effectiveness Indications Statements in Veterinary Biologics Labeling; Notice of Public Meeting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... Animal and Plant Health Inspection Service Effectiveness Indications Statements in Veterinary Biologics... veterinary biological products, as well as other interested individuals, that we will be holding a public... veterinary biologics labeling. We are also making the concept paper available for review and comment....

  4. Tsunami early warning and decision support

    NASA Astrophysics Data System (ADS)

    Steinmetz, T.; Raape, U.; Teßmann, S.; Strobl, C.; Friedemann, M.; Kukofka, T.; Riedlinger, T.; Mikusch, E.; Dech, S.

    2010-09-01

    An innovative newly developed modular and standards based Decision Support System (DSS) is presented which forms part of the German Indonesian Tsunami Early Warning System (GITEWS). The GITEWS project stems from the effort to implement an effective and efficient Tsunami Early Warning and Mitigation System for the coast of Indonesia facing the Sunda Arc along the islands of Sumatra, Java and Bali. The geological setting along an active continental margin which is very close to densely populated areas is a particularly difficult one to cope with, because potential tsunamis' travel times are thus inherently short. National policies require an initial warning to be issued within the first five minutes after an earthquake has occurred. There is an urgent requirement for an end-to-end solution where the decision support takes the entire warning chain into account. The system of choice is based on pre-computed scenario simulations and rule-based decision support which is delivered to the decision maker through a sophisticated graphical user interface (GUI) using information fusion and fast information aggregation to create situational awareness in the shortest time possible. The system also contains risk and vulnerability information which was designed with the far end of the warning chain in mind - it enables the decision maker to base his acceptance (or refusal) of the supported decision also on regionally differentiated risk and vulnerability information (see Strunz et al., 2010). While the system strives to provide a warning as quickly as possible, it is not in its proper responsibility to send and disseminate the warning to the recipients. The DSS only broadcasts its messages to a dissemination system (and possibly any other dissemination system) which is operated under the responsibility of BMKG - the meteorological, climatological and geophysical service of Indonesia - which also hosts the tsunami early warning center. The system is to be seen as one step towards the development of a "system of systems" enabling all countries around the Indian Ocean to have such early warning systems in place. It is within the responsibility of the UNESCO Intergovernmental Oceonographic Commission (IOC) and in particular its Intergovernmental Coordinating Group (ICG) to coordinate and give recommendations for such a development. Therefore the Decision Support System presented here is designed to be modular, extensible and interoperable (Raape et al., 2010).

  5. Effects of different discount levels on healthy products coupled with a healthy choice label, special offer label or both: results from a web-based supermarket experiment

    PubMed Central

    2013-01-01

    Background Two strategies commonly recommended to improve population diets include food labels and food taxes/subsidies. The aim of this study was to examine the effects of both strategies separately and in combination. Findings An experiment with a 3x3 factorial design was conducted, including: three levels of price reduction (10%; 25%; and 50%) x three labels (‘special offer’, ‘healthy choice’ and ‘special offer & healthy choice’) on healthy foods defined following the Choices front-of-pack nutrition label. N?=?109 participants completed the experiment by conducting a typical weekly shop for their household at a three-dimensional web-based supermarket. Data were analysed using analysis of covariance. Participants receiving a 50% price discount purchased significantly more healthy foods for their household in a typical weekly shop than the 10% discount (+8.7 items; 95%CI?=?3.8-13.6) and the 25% discount group (+7.7 items; 95%CI?=?2.74 – 12.6). However, the proportion of healthy foods was not significantly higher and the discounts lead to an increased amount of energy purchased. No significant effects of the labels were found. Conclusion This study brings some relevant insights into the effects of price discounts on healthier foods coupled with different labels and shows that price effects over shadowed food labels. However, price discounts seem to have ambiguous effects; they do encourage the purchase of healthy products, but also lead to increased energy purchases. More research is needed to examine how pricing strategies can work in directing consumers towards interchanging unhealthier options for healthier alternatives. PMID:23680347

  6. Early warning signals in complex ecosystems

    NASA Astrophysics Data System (ADS)

    Weaver, I. S.; Dyke, J. G.

    2015-11-01

    Given the potential for elements of the Earth system to undergo rapid, hard to reverse changes in state, there is a pressing need to establish robust methods to produce early warning signals of such events. Here we present a conceptual ecosystem model in which a diversity of stable states emerge, along with rapid changes, referred to as critical transitions, as a consequence of external driving and non-linear ecological dynamics. We are able to produce robust early warning signals that precede critical transitions. However, we show that there is no correlation between the magnitude of the signal and magnitude or reversibility of any individual critical transition. We discuss these findings in the context of ecosystem management prior to and post critical transitions. We argue that an understanding of the dynamics of the systems is necessary both for management prior and post critical transitions and the effective interpretation of any early warning signal that may be produced for that system.

  7. Automatic earthquake confirmation for early warning system

    NASA Astrophysics Data System (ADS)

    Kuyuk, H. S.; Colombelli, S.; Zollo, A.; Allen, R. M.; Erdik, M. O.

    2015-07-01

    Earthquake early warning studies are shifting real-time seismology in earthquake science. They provide methods to rapidly assess earthquakes to predict damaging ground shaking. Preventing false alarms from these systems is key. Here we developed a simple, robust algorithm, Authorizing GRound shaking for Earthquake Early warning Systems (AGREEs), to reduce falsely issued alarms. This is a network threshold-based algorithm, which differs from existing approaches based on apparent velocity of P and S waves. AGREEs is designed to function as an external module to support existing earthquake early warning systems (EEWSs) and filters out the false events, by evaluating actual shaking near the epicenter. Our retrospective analyses of the 2009 L'Aquila and 2012 Emilia earthquakes show that AGREEs could help an EEWS by confirming the epicentral intensity. Furthermore, AGREEs is able to effectively identify three false events due to a storm, a teleseismic earthquake, and broken sensors in Irpinia Seismic Network, Italy.

  8. Proposal for tunnel-field-effect-transistor as ultra-sensitive and label-free Deblina Sarkar and Kaustav Banerjee

    E-print Network

    Proposal for tunnel-field-effect-transistor as ultra-sensitive and label-free biosensors Deblina. Phys. 110, 104702 (2011) Cerium oxide-chitosan based nanobiocomposite for food borne mycotoxin://apl.aip.org/authors #12;Proposal for tunnel-field-effect-transistor as ultra-sensitive and label-free biosensors Deblina

  9. The Global Emergency Observation and Warning System

    NASA Technical Reports Server (NTRS)

    Bukley, Angelia P.; Mulqueen, John A.

    1994-01-01

    Based on an extensive characterization of natural hazards, and an evaluation of their impacts on humanity, a set of functional technical requirements for a global warning and relief system was developed. Since no technological breakthroughs are required to implement a global system capable of performing the functions required to provide sufficient information for prevention, preparedness, warning, and relief from natural disaster effects, a system is proposed which would combine the elements of remote sensing, data processing, information distribution, and communications support on a global scale for disaster mitigation.

  10. 1Bureau of Meteorology | Water Information > INFORMATION SHEET 6 > Flood Forecasting and Warning Services Flood Forecasting

    E-print Network

    Greenslade, Diana

    SHEET 6 1Bureau of Meteorology | Water Information > INFORMATION SHEET 6 > Flood Forecasting and Warning Services Flood Forecasting and Warning Services The Bureau of Meteorology (the Bureau) is responsible for providing an effective flood forecasting and warning service in each Australian state

  11. Longer Term Impact of Cigarette Package Warnings in Australia Compared with the United Kingdom and Canada

    ERIC Educational Resources Information Center

    Li, Lin; Borland, Ron; Yong, Hua; Cummings, Kenneth M.; Thrasher, James F.; Hitchman, Sara C.; Fong, Geoffrey T.; Hammond, David; Bansal-Travers, Maansi

    2015-01-01

    This study examines the effects of different cigarette package warnings in Australia, Canada and the United Kingdom up to 5 years post-implementation. The data came from the International Tobacco Control Surveys. Measures included salience of warnings, cognitive responses, forgoing cigarettes and avoiding warnings. Although salience of the UK…

  12. Heavy atom labeled nucleotides for measurement of kinetic isotope effects.

    PubMed

    Weissman, Benjamin P; Li, Nan-Sheng; York, Darrin; Harris, Michael; Piccirilli, Joseph A

    2015-11-01

    Experimental analysis of kinetic isotope effects represents an extremely powerful approach for gaining information about the transition state structure of complex reactions not available through other methodologies. The implementation of this approach to the study of nucleic acid chemistry requires the synthesis of nucleobases and nucleotides enriched for heavy isotopes at specific positions. In this review, we highlight current approaches to the synthesis of nucleic acids enriched site specifically for heavy oxygen and nitrogen and their application in heavy atom isotope effect studies. This article is part of a special issue titled: Enzyme Transition States from Theory and Experiment. PMID:25828952

  13. Evaluating Warning Sound Urgency with Reaction Times

    ERIC Educational Resources Information Center

    Suied, Clara; Susini, Patrick; McAdams, Stephen

    2008-01-01

    It is well-established that subjective judgments of perceived urgency of alarm sounds can be affected by acoustic parameters. In this study, the authors investigated an objective measurement, the reaction time (RT), to test the effectiveness of temporal parameters of sounds in the context of warning sounds. Three experiments were performed using a…

  14. Directing gaze: the effect of disclaimer labels on women's visual attention to fashion magazine advertisements.

    PubMed

    Bury, Belinda; Tiggemann, Marika; Slater, Amy

    2014-09-01

    In an effort to combat the known negative effects of exposure to unrealistic thin ideal images, there is increasing worldwide pressure on fashion, media and advertising industries to disclose when images have been digitally altered. The current study used eye tracking technology to investigate experimentally how digital alteration disclaimer labels impact women's visual attention to fashion magazine advertisements. Participants were 60 female undergraduate students who viewed four thin ideal advertisements with either no disclaimer, a generic disclaimer, or a specific more detailed disclaimer. It was established that women did attend to the disclaimers. The nature of the disclaimer had no effect on time spent looking at particular body parts, but did affect the direction of gaze following reading of the disclaimer. This latter effect was found to be greater for women high on trait appearance comparison. Further research is paramount in guiding effective policy around the use of disclaimer labels. PMID:24997284

  15. 49 CFR 172.407 - Label specifications.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...label with a one color background of green, red or blue. (ii) White must be used for...Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh Street...warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For...

  16. 49 CFR 172.407 - Label specifications.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...label with a one color background of green, red or blue. (ii) White must be used for...Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh Street...warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For...

  17. 49 CFR 172.407 - Label specifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...label with a one color background of green, red or blue. (ii) White must be used for...Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh Street...warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For...

  18. 49 CFR 172.407 - Label specifications.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...label with a one color background of green, red or blue. (ii) White must be used for...Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh Street...warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For...

  19. Correlation between phosphatidylinositol labeling and contraction in rabbit aorta: effect of alpha-1 adrenergic activation

    SciTech Connect

    Villalobos-Molina, R.; Uc, M.; Hong, E.; Garcia-Sainz, J.A.

    1982-07-01

    Activation of rabbit aortic strips with alpha adrenergic agonists increased the labeling (with (/sup 32/P)Pi) of phosphatidylinositol (PI) and phosphatidic acid and contracted the vascular preparations in dose-related fashion. Epinephrine, norepinephrine and methoxamine produced maximal effects, whereas clonidine behaved as partial agonist and B-HT 933 (2-amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazole-(5,4-d) azepin dihydrochloride) was almost without activity in the two experimental models used. Phenylephrine was a full agonist in producing contraction, but failed to elicit the maximal increase in PI labeling. The EC50 values to produce contraction of aortic strips were lower for all agonists than those required to increase the incorporation of radioactive phosphate into PI, but there was a good correlation between the two sets of data. The increased PI labeling and contraction of aortic strips induced by epinephrine were antagonized by prazosin and yohimbine in dose-related fashion, but the first alpha blocker was about three orders of magnitude more potent than the second in antagonizing the two effects. The present results indicate that both stimulation of PI labeling and contraction are mediated through activation of alpha-1 adrenoceptors in rabbit aorta.

  20. Warning: Don't wear medication patches during MRI By LAURAN NEERGAARD, AP Medical Writer

    E-print Network

    California at San Diego, University of

    for chemotherapy recipients. But the Food and Drug Administration just discovered that some are missing a key." As for patch makers, FDA is reviewing every product's label to be sure ones that are supposed to carry the safety warning do. Some may be missing because a patch was reformulated to add metal after its label

  1. Rock Music Gets a Label.

    ERIC Educational Resources Information Center

    Cutietta, Robert

    1986-01-01

    A group called Parents Music Resource Center (PMRC) has captured the media spotlight with a proposal to have warning labels placed on music albums containing sexually explicit or violent lyrics. Major record companies have agreed to a version of the PMRC's demands for a one-year trial period, beginning in 1986. (RM)

  2. Linking the evolution and form of warning coloration in nature.

    PubMed

    Stevens, Martin; Ruxton, Graeme D

    2012-02-01

    Many animals are toxic or unpalatable and signal this to predators with warning signals (aposematism). Aposematic appearance has long been a classical system to study predator-prey interactions, communication and signalling, and animal behaviour and learning. The area has received considerable empirical and theoretical investigation. However, most research has centred on understanding the initial evolution of aposematism, despite the fact that these studies often tell us little about the form and diversity of real warning signals in nature. In contrast, less attention has been given to the mechanistic basis of aposematic markings; that is, 'what makes an effective warning signal?', and the efficacy of warning signals has been neglected. Furthermore, unlike other areas of adaptive coloration research (such as camouflage and mate choice), studies of warning coloration have often been slow to address predator vision and psychology. Here, we review the current understanding of warning signal form, with an aim to comprehend the diversity of warning signals in nature. We present hypotheses and suggestions for future work regarding our current understanding of several inter-related questions covering the form of warning signals and their relationship with predator vision, learning, and links to broader issues in evolutionary ecology such as mate choice and speciation. PMID:22113031

  3. 76 FR 44475 - Labeling for Bronchodilators To Treat Asthma; Cold, Cough, Allergy, Bronchodilator, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ...Labeling for Bronchodilators To Treat Asthma; Cold, Cough, Allergy, Bronchodilator...additional warnings (e.g., an ``Asthma alert'') and to revise the indications...Labeling of OTC Drug Products Used To Treat Asthma II. History of the Development of...

  4. 76 FR 82129 - Medical Devices; Ovarian Adnexal Mass Assessment Score Test System; Labeling; Black Box Restrictions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ...Assessment Score Test System; Labeling; Black Box Restrictions AGENCY: Food and Drug...controls guidance document must be in a black box and must appear in all labeling, advertising, and promotional material. The black box warning mitigates the risk to...

  5. 49 CFR 234.259 - Warning time.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Warning time. 234.259 Section 234.259..., Inspection, and Testing Inspections and Tests § 234.259 Warning time. Each crossing warning system shall be tested for the prescribed warning time at least once every 12 months and when the warning system...

  6. Tobacco Health Warning Messages on Plain Cigarette Packs and in Television Campaigns: A Qualitative Study with Australian Socioeconomically Disadvantaged Smokers

    ERIC Educational Resources Information Center

    Guillaumier, Ashleigh; Bonevski, Billie; Paul, Christine

    2015-01-01

    Television advertisements, packaging regulations and health warning labels (HWLs) are designed to communicate anti-smoking messages to large number of smokers. However, only a few studies have examined how high smoking prevalence groups respond to these warnings. This study explored how socioeconomically disadvantaged smokers engage with health…

  7. forthcoming in the American Journal of Agricultural Economics Effects of the Private-Label Invasion in Food Industries

    E-print Network

    Perloff, Jeffrey M.

    in Food Industries Abstract Using supermarket scanner data, we test a variety of hypotheses from trade journals about the invasion of private-label food products. According to conventional industry wisdom, name reviewers made very helpful suggestions. #12;Effects of the Private-Label Invasion in Food Industries When

  8. Agonist-induced alterations in lymphocyte. beta. -adrenergic receptor photoaffintiy labelling: effects of phenylarsine oxide

    SciTech Connect

    Feldman, R.D.; McArdle, W.; Lai, C.

    1986-03-01

    In several models, desensitization of the ..beta..-adrenergic receptor (..beta..AR) is associated with a decrease in binding of hydrophilic but not hydrophobic ..beta..AR ligands. This suggests a sequestration of cell surface ..beta..AR. Desensitization of the lymphobyte ..beta..AR is also associated with a selective reduction in the photoaffinity labelling of a 55K ..beta..AR protein as compared to a 68K ..beta..AR protein. In order to examine the relationship between sequestration and reduction in labelling of the 55K peptide, the authors have studied the effect of phenylarsine oxide (PAO; an inhibitor of sequestration) on lymphocyte ..beta..AR desensitization. Incubation of cells with PAO prior to desensitization did not block the consequent reduction in isoproterenol-stimulated adenylate cyclase activity. However, the agonist-induced reduction in binding of the hydrophilic ..beta..AR ligand CGP-12177 was blocked by PAO (without PAO:57 +/- 4% of control, with PAO: 97 +/- 2% of control). Photolabelling studies with (/sup 125/I) iodocyanopindolol diazirine revealed that PAO pretreatment also blocked the selective loss in labelling of the 55K ..beta..AR protein seen with desensitization. These data suggest that loss of labelling of the 55K protein of the ..beta..AR is closely coupled to ..beta..AR sequestration.

  9. Crowdsourced earthquake early warning

    PubMed Central

    Minson, Sarah E.; Brooks, Benjamin A.; Glennie, Craig L.; Murray, Jessica R.; Langbein, John O.; Owen, Susan E.; Heaton, Thomas H.; Iannucci, Robert A.; Hauser, Darren L.

    2015-01-01

    Earthquake early warning (EEW) can reduce harm to people and infrastructure from earthquakes and tsunamis, but it has not been implemented in most high earthquake-risk regions because of prohibitive cost. Common consumer devices such as smartphones contain low-cost versions of the sensors used in EEW. Although less accurate than scientific-grade instruments, these sensors are globally ubiquitous. Through controlled tests of consumer devices, simulation of an Mw (moment magnitude) 7 earthquake on California’s Hayward fault, and real data from the Mw 9 Tohoku-oki earthquake, we demonstrate that EEW could be achieved via crowdsourcing. PMID:26601167

  10. Crowdsourced earthquake early warning.

    PubMed

    Minson, Sarah E; Brooks, Benjamin A; Glennie, Craig L; Murray, Jessica R; Langbein, John O; Owen, Susan E; Heaton, Thomas H; Iannucci, Robert A; Hauser, Darren L

    2015-04-01

    Earthquake early warning (EEW) can reduce harm to people and infrastructure from earthquakes and tsunamis, but it has not been implemented in most high earthquake-risk regions because of prohibitive cost. Common consumer devices such as smartphones contain low-cost versions of the sensors used in EEW. Although less accurate than scientific-grade instruments, these sensors are globally ubiquitous. Through controlled tests of consumer devices, simulation of an M w (moment magnitude) 7 earthquake on California's Hayward fault, and real data from the M w 9 Tohoku-oki earthquake, we demonstrate that EEW could be achieved via crowdsourcing. PMID:26601167

  11. Effect of antiarrhythmic drugs on In-111-labeled leukocytes: chemotaxis and adherence to nylon wool

    SciTech Connect

    Thakur, M.L.; Walsh, L.J.; Zaret, B.L.; Gottschalk, A.

    1982-02-01

    The influence of lidocaine (L) and procainamide (P) on the chemotactic ability and adherence to nylon wool of In-111-labeled human polymorphonuclear leukocytes (PMNs) was investigated. At the normal therapeutic levels of L (0.022 mM whole blood) or P (0.03 mM whole blood) no change in PMN function was observed. However, at and above five times the aforementioned blood levels of L, significant reduction in the chemotactic ability of PMNs was noted (P <0.005). The adverse effects of In-111 radiation appeared insignificant at all L or P concentrations during the 3-hr observation period. The labeled PMNs were resistant to the toxic effects of a higher concentration of P than that of L, and the reduction in PMN chemotaxis and adherence to nylon wool was not apparent until the P concentration reached 1.5 mM.

  12. Effect of antiarrhythmic drugs on In-111-labeled leukocytes: chemotaxis and adherence to nylon wool

    SciTech Connect

    Thakur, M.L.; Walsh, L.J.; Zaret, B.L.; Gottschalk, A.

    1982-02-01

    The influence of lidocaine (L) and procainamide (P) on the chemotactic ability and adherence to nylon wool of In-111-labeled human polymorphonuclear leukocytes (PMNs) was investigated. At the normal therapeutic levels of L (0.022 mM whole blood) or P (0.03 mM whole blood) no change in PMN function was observed. However, at and above five times the aforementioned blood levels of L, significant reduction in the chemotactic ability of PMNs was noted (p less than 0.005). The adverse effects of In-111 radiation appeared insignificant at all L or P concentrations during the 3-hr observation period. The labeled PMNs were resistant to the toxic effects of a higher concentration of P than that of L, and the reduction in PMN chemotaxis and adherence to nylon wool was not apparent until the P concentration reached 1.5 mM.

  13. Car Gestures - Advisory warning using additional steering wheel angles.

    PubMed

    Maag, Christian; Schneider, Norbert; Lübbeke, Thomas; Weisswange, Thomas H; Goerick, Christian

    2015-10-01

    Advisory warning systems (AWS) notify the driver about upcoming hazards. This is in contrast to the majority of currently deployed advanced driver assistance systems (ADAS) that manage emergency situations. The target of this study is to investigate the effectiveness, acceptance, and controllability of a specific kind of AWS that uses the haptic information channel for warning the driver. This could be beneficial, as alternatives for using the visual modality can help to reduce the risk of visual overload. The driving simulator study (N=24) compared an AWS based on additional steering wheel angle control (Car Gestures) with a visual warning presented in a simulated head-up display (HUD). Both types of warning were activated 3.5s before the hazard object was reached. An additional condition of unassisted driving completed the experimental design. The subjects encountered potential hazards in a variety of urban situations (e.g. a pedestrian standing on the curbs). For the investigated situations, subjective ratings show that a majority of drivers prefer visual warnings over haptic information via gestures. An analysis of driving behavior indicates that both warning approaches guide the vehicle away from the potential hazard. Whereas gestures lead to a faster lateral driving reaction (compared to HUD warnings), the visual warnings result in a greater safety benefit (measured by the minimum distance to the hazard object). A controllability study with gestures in the wrong direction (i.e. leading toward the hazard object) shows that drivers are able to cope with wrong haptic warnings and safety is not reduced compared to unassisted driving as well as compared to (correct) haptic gestures and visual warnings. PMID:26264518

  14. Comparison of several indium-111 ligands in labeling blood cells: effect of diethylpyrocarbonate and CO/sub 2/

    SciTech Connect

    Goedemans, W.T.; de Jong, M.M.

    1987-06-01

    The effect of oxine sulfate, oxine sulfonate, tropolone, and Merc (2 mercaptopyridine-1-oxide) were compared with oxine, with respect to their capability of labeling blood cells when complexed to indium-111 (/sup 111/In). Indium-111 oxine sulfate performed similarly to (/sup 111/In)oxine with regard to cell labeling capability. Indium-111 oxine sulfonate had no labeling ability. Indium-111 tropolone and Merc were not superior to (/sup 111/In)oxine as cell labeling agents. Carbon dioxide (CO/sub 2/) and a CO/sub 2/ generating compound, diethyl pyrocarbonate, dramatically improved the cell labeling ability in plasma of (/sup 111/In)tropolone and Merc. In the case of oxine, this improvement was less distinct. Theoretical aspects of the CO/sub 2/ cell labeling stimulating effect are discussed in terms of intra- and extracellular transferrin and lactoferrin iron (indium) binding capacity. Indium-111 tropolone behaved favorably with respect to inhibition of leukocyte migration, compared with oxine and Merc. Combined with the property of easy cell labeling and good solubility in water, also in the complexed state, tropolone must be regarded as the most suitable cell labeling ligand.

  15. Effect of reversible reactions on isotope label redistribution--analysis of the pentose phosphate pathway.

    PubMed

    Follstad, B D; Stephanopoulos, G

    1998-03-15

    The pentose phosphate pathway plays several key roles in metabolism including supply of biosynthetic carbon skeletons and reducing power. Previous research has focused on determining the fluxes through the reactions of this pathway using carbon-labeled substrates and models that make certain assumptions about the reversibility of the transketolase and transaldolase reactions in the nonoxidative pathway. These assumptions, however, have resulted in inconsistencies between the predicted carbon label distributions using these models and those determined experimentally. A general metabolic reaction network model developed in this paper and applied to the pentose phosphate pathway not only incorporates reaction reversibility but also accounts for the effect of individually varying extents of reaction reversibility on labeled carbon fractional enrichment values for intermediate metabolites. In addition, an algorithm is presented that can be used to calculate the three individual transaldolase and transketolase extents of reversibility. The results of this method show that varying extents of reaction reversibility have an observable effect on the metabolite carbon label distributions which can in turn affect flux calculation for other parts of the metabolic network such as the tricarboxylic acid cycle. In addition, the observability of reversibility extent and accuracy of flux calculations depend on the particular choice of metabolite carbon enrichments measured. In particular, [6-13C]hexose 6-phosphate and [4-13C]erythrose 4-phosphate carbon enrichment values resulting from [1-13C]glucose feeding contained more information as compared to those from ribose 5-phosphate. This analysis was applied to literature data of metabolite carbon labeling that resulted from supplying either 13C- or 14C-enriched substrates to several cell types growing under various conditions. The specific activities of metabolite carbon atoms taken from rat epididymal adipose tissue, goosefish islet cells, Corynebacterium glutamicum, and Escherichia coli supplied with either [2-14C]glucose or [1-13C]glucose demonstrate how reversibility is present in the pentose phosphate pathway and the extents of reversibility can be estimated from labeled carbon data sets. PMID:9546650

  16. 27 CFR 16.21 - Mandatory label information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Mandatory label information. 16.21 Section 16.21 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS ALCOHOLIC BEVERAGE HEALTH WARNING STATEMENT Health Warning Statement Requirements for Alcoholic Beverages...

  17. 27 CFR 16.21 - Mandatory label information.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Mandatory label information. 16.21 Section 16.21 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL ALCOHOLIC BEVERAGE HEALTH WARNING STATEMENT Health Warning Statement Requirements for Alcoholic Beverages...

  18. Designing Fatigue Warning Systems: The perspective of professional drivers.

    PubMed

    Meng, Fanxing; Li, Shuling; Cao, Lingzhi; Peng, Qijia; Li, Musen; Wang, Chunhui; Zhang, Wei

    2016-03-01

    Professional drivers have been characterized as experiencing heavy fatigue resulting from long driving time in their daily work. This study aimed to explore the potential demand of Fatigue Warning Systems (FWSs) among professional drivers as a means of reducing the danger of fatigue driving and to examine their opinions regarding the design of FWSs. Six focus groups with 35 participants and a questionnaire survey with 600 respondents were conducted among Chinese truck and taxi drivers to collect qualitative and quantitative data concerning the current situation of fatigue driving and opinions regarding the design of FWSs. The results revealed that both truck and taxi drivers had a positive attitude toward FWSs, and they hoped this system could not only monitor and warn them regarding their fatigue but also somewhat relieve their fatigue before they could stop and rest. As for warning signals, participants preferred auditory warnings, as opposed to visual, vibrotactile or electric stimuli. Interestingly, it was proposed that verbal warnings involving the information regarding consequences of fatigue driving or the wishes of drivers' family members would be more effective. Additionally, different warning patterns, including graded, single and continuous warnings, were discussed in the focus group. Finally, the participants proposed many other suggestions, as well as their concerns regarding FWSs, which will provide valuable information for companies who wish to develop FWSs for professional drivers. PMID:26482894

  19. 49 CFR 234.259 - Warning time.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Warning time. 234.259 Section 234.259... time. Each crossing warning system shall be tested for the prescribed warning time at least once every... devices that accurately determine actual warning time may be used in performing such tests....

  20. February 2001 Flood Warning Services in Victoria

    E-print Network

    Greenslade, Diana

    February 2001 Flood Warning Services in Victoria Arrangements for VICTORIAN FLOOD WARNING CONSULTATIVE COMMITTEE #12;Arrangements for Flood Warning Services in Victoria VICTORIAN FLOOD WARNING, `Geelong Advertiser' Title page: Bulleen Road at the Yarra River, Melbourne. Flooding a long time ago

  1. 49 CFR 234.259 - Warning time.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Warning time. 234.259 Section 234.259... time. Each crossing warning system shall be tested for the prescribed warning time at least once every... devices that accurately determine actual warning time may be used in performing such tests....

  2. Attention mediates the effect of nutrition label information on consumers' choice. Evidence from a choice experiment involving eye-tracking.

    PubMed

    Bialkova, Svetlana; Grunert, Klaus G; Juhl, Hans Jørn; Wasowicz-Kirylo, Grazyna; Stysko-Kunkowska, Malgorzata; van Trijp, Hans C M

    2014-05-01

    In two eye-tracking studies, we explored whether and how attention to nutrition information mediates consumers' choice. Consumers had to select either the healthiest option or a product of their preference within an assortment. On each product a particular label (Choices logo, monochrome GDA label, or color-coded GDA label) communicated the product's nutrient profile. In study 1, participants had to select from 4 products differentiated, in addition to the nutrition information, by flavor (strawberry, muesli, apple, chocolate; varied within participants) and brand (local vs. global, varied between participants). Study 2 further explored brand effect within-participants, and thus only 2 flavors (strawberry, chocolate) were presented within an assortment. Actual choice made, response time and eye movements were recorded. Respondents fixated longer and more often on products with color-coded GDAs label than on products with monochrome GDAs or Choices logo. A health goal resulted in longer and more frequent fixations in comparison to a preference goal. Products with color-coded and monochrome GDAs had the highest likelihood of being chosen, and this effect was related to the attention-getting property of the label (irrespective of brand and flavor effects). The product fixated most had the highest likelihood of being chosen. These results suggest that attention mediates the effect of nutrition labels on choice. PMID:24503332

  3. Warning Signs of Mental Illnesses

    MedlinePLUS

    ... in personal care Mood changes — Rapid or dramatic shifts in feelings One or two of these symptoms ... clear signs of a diagnosable mental illness, these “red flag” early warning symptoms can be frightening and ...

  4. Aircraft Cabin Turbulence Warning Experiment

    NASA Technical Reports Server (NTRS)

    Bogue, Rodney K.; Larcher, Kenneth

    2006-01-01

    New turbulence prediction technology offers the potential for advance warning of impending turbulence encounters, thereby allowing necessary cabin preparation time prior to the encounter. The amount of time required for passengers and flight attendants to be securely seated (that is, seated with seat belts fastened) currently is not known. To determine secured seating-based warning times, a consortium of aircraft safety organizations have conducted an experiment involving a series of timed secured seating trials. This demonstrative experiment, conducted on October 1, 2, and 3, 2002, used a full-scale B-747 wide-body aircraft simulator, human passenger subjects, and supporting staff from six airlines. Active line-qualified flight attendants from three airlines participated in the trials. Definitive results have been obtained to provide secured seating-based warning times for the developers of turbulence warning technology

  5. LIVE DEMONSTRATION OF DISTANT EARLY WARNING SYSTEM

    NASA Astrophysics Data System (ADS)

    Hammitzsch, M.; Lendholt, M.; Wächter, J.

    2009-12-01

    The DEWS (Distant Early Warning System) [1] project, funded under the 6th Framework Programme of the European Union, has the objective to create a new generation of interoperable early warning systems based on an open sensor platform. This platform integrates OGC [2] SWE [3] compliant sensor systems for the rapid detection of earthquakes, for the monitoring of sea level, ocean floor events, and ground displacements. Based on the upstream information flow DEWS focuses on the improvement of downstream capacities of warning centres especially by improving information logistics for effective and targeted warning message aggregation for a multilingual environment. Multiple telecommunication channels will be used for the dissemination of warning messages. Wherever possible, existing standards have been integrated. The Command and Control User Interface (CCUI), a rich client application based on Eclipse RCP (Rich Client Platform) [4] and the open source GIS uDig [5], integrates various OGC services. Using WMS (Web Map Service) [6] and WFS (Web Feature Service) [7] spatial data are utilized to depict the situation picture and to integrate a simulation system via WPS (Web Processing Service) [8] to identify affected areas. Warning messages are compiled and transmitted in the OASIS [9] CAP (Common Alerting Protocol) [10] standard together with addressing information defined via EDXL-DE (Emergency Data Exchange Language - Distribution Element) [11]. Internal interfaces are realized with SOAP [12] web services. Based on results of GITEWS [13] - in particular the GITEWS Tsunami Service Bus [14] - the DEWS approach provides an implementation for tsunami early warning systems. The introductory part of the demonstration briefly explains the DEWS project, the CCUI in conjunction with operators’ workflow, the system architecture, details of information logistics and the virtual scenario of live demonstration. The live demonstration exhibits the CCUI on screen and the service environment of DEWS working in the background. The demonstration runs through a virtual Tsunami threat located in the Andaman Sea in front of Thailand; Beginning with the detection of an earthquake of critical magnitude and the calculation of early Tsunami predictions; Continuing with sea level measurements and the refinement of Tsunami predictions; Finally reaching the dissemination of warning messages via SMS, mail and other channels. REFERENCES [1] DEWS, www.dews-online.org [2] OGC, www.opengeospatial.org [3] SWE, www.opengeospatial.org/projects/groups/sensorweb [4] Eclipse RCP, www.eclipse.org/home/categories/rcp.php [5] uDig, udig.refractions.net [6] WMS, www.opengeospatial.org/standards/wms [7] WFS, www.opengeospatial.org/standards/wfs [8] WPS, www.opengeospatial.org/standards/wps [9] OASIS, www.oasis-open.org [10] CAP, www.oasis-open.org/specs/#capv1.1 [11] EDXL-DE, www.oasis-open.org/specs/#edxlde-v1.0 [12] SOAP, www.w3.org/TR/soap [13] GITEWS (German Indonesian Tsunami Early Warning System) is a project of the German Federal Government to aid the reconstruction of the tsunami-prone Indian Ocean region, www.gitews.org [14] The Tsunami Service Bus is the GITEWS sensor system integration platform offering standardised services for the detection and monitoring of tsunamis

  6. Satellite Threat Warning and Attack Reporting

    SciTech Connect

    Hilland, D.; Phipps, G.; Jingle, C.; Newton, G.

    1997-12-31

    The Air Force Research Laboratory`s Satellite Threat Warning and Attack Reporting (STW/AR) program will provide technologies for advanced threat warning and reporting of radio frequency (RF) and laser threats. The STW/AR program objectives are: (a) develop cost- effective technologies to detect, identify, locate, characterize, and report attacks or interference against U.S. and Allied satellites. (b) demonstrate innovative, light-weight, low-power, laser and RF sensors. The program focuses on the demonstration of RF and laser sensors. The RF sensor effort includes the investigation of interferometric antenna arrays, multi-arm spiral and butler matrix antennas, wideband receivers, adaptive processors, and improved processing algorithms. The laser sensor effort includes the investigation of alternative detectors, broadband grating and optical designs, active pixel sensing, and improved processing algorithms.

  7. 21 CFR 201.307 - Sodium phosphates; package size limitation, warnings, and directions for over-the-counter sale.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Sodium phosphates; package size limitation, warnings, and directions for over-the-counter sale. 201.307 Section 201.307 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING Specific Labeling Requirements for Specific Drug Products...

  8. 16 CFR 1205.2 - Effective date.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.2 Effective date. This standard applies to all rotary walk behind power lawn mowers manufactured after June 30, 1982, except § 1205.6 Warning labels, applies to rotary and reel-type walk-behind power lawn mowers manufactured after December...

  9. 16 CFR 1205.2 - Effective date.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.2 Effective date. This standard applies to all rotary walk behind power lawn mowers manufactured after June 30, 1982, except § 1205.6 Warning labels, applies to rotary and reel-type walk-behind power lawn mowers manufactured after December...

  10. 16 CFR 1205.2 - Effective date.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.2 Effective date. This standard applies to all rotary walk behind power lawn mowers manufactured after June 30, 1982, except § 1205.6 Warning labels, applies to rotary and reel-type walk-behind power lawn mowers manufactured after December...

  11. 16 CFR 1205.2 - Effective date.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.2 Effective date. This standard applies to all rotary walk behind power lawn mowers manufactured after June 30, 1982, except § 1205.6 Warning labels, applies to rotary and reel-type walk-behind power lawn mowers manufactured after December...

  12. 16 CFR 1205.2 - Effective date.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... STANDARD FOR WALK-BEHIND POWER LAWN MOWERS The Standard § 1205.2 Effective date. This standard applies to all rotary walk behind power lawn mowers manufactured after June 30, 1982, except § 1205.6 Warning labels, applies to rotary and reel-type walk-behind power lawn mowers manufactured after December...

  13. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not...

  14. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not...

  15. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not...

  16. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not...

  17. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not...

  18. Speech, "Inner Speech," and the Development of Short-Term Memory: Effects of Picture-Labeling on Recall.

    ERIC Educational Resources Information Center

    Hitch, Graham J.; And Others

    1991-01-01

    Reports on experiments to determine effects of overt speech on children's use of inner speech in short-term memory. Word length and phonemic similarity had greater effects on older children and when pictures were labeled at presentation. Suggests that speaking or listening to speech activates an internal articulatory loop. (Author/GH)

  19. Effect of the label of oligosaccharide acceptors on the kinetic parameters of nasturtium seed xyloglucan endotransglycosylase (XET).

    PubMed

    Kosík, Ond?ej; Garajová, So?a; Matulová, Mária; Rehulka, Pavel; Stratilová, Eva; Farkaš, Vladimír

    2011-02-01

    Fluorescently labeled derivatives of a xyloglucan (XG) nonasaccharide Glc(4)Xyl(3)Gal(2) (XLLG) were used as glycosyl acceptors in assays of xyloglucan endotransglycosylase (XET) from germinated nasturtium (Tropaeolum majus) seeds. We have investigated how the type of the oligosaccharide label influences the kinetic parameters of the reaction. The fluorescent probes used to label XLLG were anthranilic acid (AA), 8-aminonaphtalene-1,3,6-trisulfonic acid (ANTS), fluorescein isothiocyanate (FITC), and sulforhodamine (SR), respectively. The obtained data were compared with those of the reactions where aldose and/or alditol forms of tritium-labeled xyloglucan-derived nonasaccharide served as the respective acceptors. Modification at C-1 of the reducing-end glucose in XLLG by substitution with the fluorophore markedly affected the kinetic parameters of the reaction. The Michaelis constants K(m) for individual acceptors increased in the order [1-(3)H]XLLGXLLG-SR>XLLG-ANTS>[1-(3)H]XLLGol>[1-(3)H]XLLG>XLLG-AA. Catalytic efficiency (expressed as k(cat)/K(m)) with XLLG labeled with SR or FITC was 15 and 28 times, respectively, higher than with the tritium-labeled natural substrate [1-(3)H]XLLG. Comparison of the kinetic parameters found with acceptors labeled with different types of labels enables to select the most effective substrates for the high-throughput assays of XET. PMID:21146161

  20. Effect of Labeling with Iron Oxide Particles or Nanodiamonds on the Functionality of Adipose-Derived Mesenchymal Stem Cells

    PubMed Central

    Blaber, Sinead P.; Hill, Cameron J.; Webster, Rebecca A.; Say, Jana M.; Brown, Louise J.; Wang, Shih-Chang; Vesey, Graham; Herbert, Benjamin Ross

    2013-01-01

    Stem cells are increasingly the focus of translational research as well as having emerging roles in human cellular therapy. To support these uses there is a need for improved methods for in vivo cell localization and tracking. In this study, we examined the effects of cell labeling on the in vitro functionality of human adipose-derived mesenchymal stem cells. Our results provide a basis for future in vivo studies investigating implanted cell fate and longevity. In particular, we investigated the effects of two different particles: micron-sized (?0.9 µm) fluorescently labeled (Dragon Green) superparamagnetic iron oxide particles (M-SPIO particles); and, carboxylated nanodiamonds of ?0.25 µm in size. The effects of labeling on the functionality of adipose-derived MSCs were assessed by in vitro morphology, osteogenic and adipogenic differentiation potential, CD marker expression, cytokine secretion profiling and quantitative proteomics of the intra-cellular proteome. The differentiation and CD marker assays for stem-like functionality were not altered upon label incorporation and no secreted or intra-cellular protein changes indicative of stress or toxicity were detected. These in vitro results indicate that the M-SPIO particles and nanodiamonds investigated in this study are biocompatible with MSCs and therefore would be suitable labels for cell localization and tracking in vivo. PMID:23301012

  1. Potential Effect of Physical Activity Calorie Equivalent (PACE) Labeling on Adult Fast Food Ordering and Exercise

    PubMed Central

    Antonelli, Ray; Viera, Anthony J.

    2015-01-01

    Introduction Numeric calorie content labels show limited efficacy in reducing the number of calories ordered from fast food meals. Physical activity calorie equivalent (PACE) labels are an alternative that may reduce the number of calories ordered in fast food meals while encouraging patrons to exercise. Methods A total of 1000 adults from 47 US states were randomly assigned via internet survey to one of four generic fast food menus: no label, calories only, calories + minutes, or calories + miles necessary to walk to burn off the calories. After completing hypothetical orders participants were asked to rate the likelihood of calorie-only and PACE labels to influence (1) food choice and (2) physical activity. Results Respondents (n = 823) ordered a median of 1580 calories from the no-label menu, 1200 from the calories-only menu, 1140 from the calories + minutes menu, and 1210 from the calories + miles menu (p = 0.0001). 40% of respondents reported that PACE labels were “very likely” to influence food item choice vs. 28% for calorie-only labels (p<0.0001). 64% of participants reported that PACE labels were “somewhat likely” or “very likely” to influence their level of physical activity vs. 49% for calorie-only labels (p<0.0001). Conclusions PACE labels may be helpful in reducing the number of calories ordered in fast food meals and may have the added benefit of encouraging exercise. PMID:26222056

  2. Label-Free and Real-Time Detection of Avian Influenza Using Nanowire Field Effect Transistors.

    PubMed

    Ahn, Jae-Hyuk; Im, Maesoon; Park, Tae Jung; Lee, Sang Yup; Choi, Yang-Kyu

    2015-09-01

    Real-time and label-free detection of antibodies from avian influenza (anti-AI) in an aqueous solution is demonstrated with the use of a nanowire field effect transistor. A real-time measurement system is constructed without leakage paths through the solution medium. The current through the nanowire changes significantly after an injection of an anti-AI solution onto the device, which was previously functionalized by the antigen of AI as a probe of anti-AI. In contrast, no significant response arises when an anti-AI solution is injected onto a non-functionalized device. Therefore, the real-time detection of specific antibody-antigen interaction of the AI is successfully implemented for a chip-based biosensor. PMID:26485932

  3. Istanbul Earthquake Early Warning System

    NASA Astrophysics Data System (ADS)

    Alcik, H.; Mert, A.; Ozel, O.; Erdik, M.

    2007-12-01

    As part of the preparations for the future earthquake in Istanbul a Rapid Response and Early Warning system in the metropolitan area is in operation. For the Early Warning system ten strong motion stations were installed as close as possible to the fault zone. Continuous on-line data from these stations via digital radio modem provide early warning for potentially disastrous earthquakes. Considering the complexity of fault rupture and the short fault distances involved, a simple and robust Early Warning algorithm, based on the exceedance of specified threshold time domain amplitude levels is implemented. The band-pass filtered accelerations and the cumulative absolute velocity (CAV) are compared with specified threshold levels. When any acceleration or CAV (on any channel) in a given station exceeds specific threshold values it is considered a vote. Whenever we have 2 station votes within selectable time interval, after the first vote, the first alarm is declared. In order to specify the appropriate threshold levels a data set of near field strong ground motions records form Turkey and the world has been analyzed. Correlations among these thresholds in terms of the epicenter distance the magnitude of the earthquake have been studied. The encrypted early warning signals will be communicated to the respective end users. Depending on the location of the earthquake (initiation of fault rupture) and the recipient facility the alarm time can be as high as about 8s. The first users of the early warning signal will be the Istanbul gas company (IGDAS) and the metro line using the immersed tube tunnel (MARMARAY). Other prospective users are power plants and power distribution systems, nuclear research facilities, critical chemical factories, petroleum facilities and high-rise buildings. In this study, different algorithms based on PGA, CAV and various definitions of instrumental intensity will be discussed and triggering threshold levels of these parameters will be studied. More complex algorithms based on artificial neural networks (ANN) can also be used [Boese et al., 2003]. ANN approach considers the problem of earthquake early-warning as a pattern recognition task. The seismic patterns can be defined by the shape and frequency content of the parts of accelerograms that are available at each time step. ANN can extract the engineering parameters PGA, CAV and instrumental intensity from these patterns, and map them to any location in the surrounded area. Boese M., Erdik, M., Wenzel, F. (2003), Artificial Neural Networks for Earthquake Early Warning, Proceedings AGU2003 Abstracts, S42B-0155

  4. Effect of HSA coated iron oxide labeling on human umbilical cord derived mesenchymal stem cells

    NASA Astrophysics Data System (ADS)

    Sanganeria, Purva; Chandra, Sudeshna; Bahadur, Dhirendra; Khanna, Aparna

    2015-03-01

    Human umbilical cord derived mesenchymal stem cells (hUC-MSCs) are known for self-renewal and differentiation into cells of various lineages like bone, cartilage and fat. They have been used in biomedical applications to treat degenerative disorders. However, to exploit the therapeutic potential of stem cells, there is a requirement of sensitive non-invasive imaging techniques which will offer the ability to track transplanted cells, bio-distribution, proliferation and differentiation. In this study, we have analyzed the efficacy of human serum albumin coated iron oxide nanoparticles (HSA-IONPs) on the differentiation of hUC-MSCs. The colloidal stability of the HSA-IONPs was tested over a long period of time (?20 months) and the optimized concentration of HSA-IONPs for labeling the stem cells was 60 ?g ml-1. Detailed in vitro assays have been performed to ascertain the effect of the nanoparticles (NPs) on stem cells. Lactate dehydrogenase (LDH) assay showed minimum release of LDH depicting the least disruptions in cellular membrane. At the same time, mitochondrial impairment of the cells was also not observed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Flow cytometry analysis revealed lesser generation of reactive oxygen species in HSA-IONPs labeled hUC-MSCs in comparison to bare and commercial IONPs. Transmission electron microscopy showed endocytic engulfment of the NPs by the hUC-MSCs. During the process, the gross morphologies of the actin cytoskeleton were found to be intact as shown by immunofluorescence microscopy. Also, the engulfment of the HSA-IONPs did not show any detrimental effect on the differentiation potential of the stem cells into adipocytes, osteocytes and chondrocytes, thereby confirming that the inherent properties of stem cells were maintained.

  5. Effect of HSA coated iron oxide labeling on human umbilical cord derived mesenchymal stem cells.

    PubMed

    Sanganeria, Purva; Chandra, Sudeshna; Bahadur, Dhirendra; Khanna, Aparna

    2015-03-27

    Human umbilical cord derived mesenchymal stem cells (hUC-MSCs) are known for self-renewal and differentiation into cells of various lineages like bone, cartilage and fat. They have been used in biomedical applications to treat degenerative disorders. However, to exploit the therapeutic potential of stem cells, there is a requirement of sensitive non-invasive imaging techniques which will offer the ability to track transplanted cells, bio-distribution, proliferation and differentiation. In this study, we have analyzed the efficacy of human serum albumin coated iron oxide nanoparticles (HSA-IONPs) on the differentiation of hUC-MSCs. The colloidal stability of the HSA-IONPs was tested over a long period of time (?20 months) and the optimized concentration of HSA-IONPs for labeling the stem cells was 60 ?g ml(-1). Detailed in vitro assays have been performed to ascertain the effect of the nanoparticles (NPs) on stem cells. Lactate dehydrogenase (LDH) assay showed minimum release of LDH depicting the least disruptions in cellular membrane. At the same time, mitochondrial impairment of the cells was also not observed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Flow cytometry analysis revealed lesser generation of reactive oxygen species in HSA-IONPs labeled hUC-MSCs in comparison to bare and commercial IONPs. Transmission electron microscopy showed endocytic engulfment of the NPs by the hUC-MSCs. During the process, the gross morphologies of the actin cytoskeleton were found to be intact as shown by immunofluorescence microscopy. Also, the engulfment of the HSA-IONPs did not show any detrimental effect on the differentiation potential of the stem cells into adipocytes, osteocytes and chondrocytes, thereby confirming that the inherent properties of stem cells were maintained. PMID:25744689

  6. 49 CFR 172.407 - Label specifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... one color background of green, red or blue. (ii) White must be used for the text and class number for... Hazardous Materials Safety, Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh... markings and hazard warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For...

  7. 49 CFR 172.407 - Label specifications.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... one color background of green, red or blue. (ii) White must be used for the text and class number for... Hazardous Materials Safety, Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh... markings and hazard warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For...

  8. 49 CFR 172.407 - Label specifications.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... one color background of green, red or blue. (ii) White must be used for the text and class number for... Hazardous Materials Safety, Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh... markings and hazard warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For...

  9. 49 CFR 172.407 - Label specifications.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... one color background of green, red or blue. (ii) White must be used for the text and class number for... Hazardous Materials Safety, Office of Hazardous Materials Standards, Room 8422, Nassif Building, 400 Seventh... markings and hazard warning labels and placards: (i) For Red—Use PANTONE ® 186 U (ii) For...

  10. 16 CFR 1508.9 - Identifying marks, warning statement, and compliance declaration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) The name and place of business (city and State) of the manufacturer, importer, distributor, and/or... dimensions shall bear identical markings. (c) The following warning shall appear on the retail carton and on... retail carton shall bear a conspicuous label stating that the crib conforms to applicable...

  11. 21 CFR 1141.10 - Required warnings.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...shall be obtained from the electronic images contained in “Cigarette Required Warnings...shall be obtained from the electronic images contained in “Cigarette Required Warnings...shall be obtained from the electronic images contained in “Cigarette Required...

  12. 21 CFR 1141.10 - Required warnings.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...shall be obtained from the electronic images contained in “Cigarette Required Warnings...shall be obtained from the electronic images contained in “Cigarette Required Warnings...shall be obtained from the electronic images contained in “Cigarette Required...

  13. 33 CFR 127.1113 - Warning signs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Waterfront Facilities Handling Liquefied Hazardous Gas Design and Construction § 127.1113 Warning signs. (a... section, bear the following text: Warning Dangerous Cargo No visitors No Smoking No Open Lights (b)...

  14. 33 CFR 127.1113 - Warning signs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Waterfront Facilities Handling Liquefied Hazardous Gas Design and Construction § 127.1113 Warning signs. (a... section, bear the following text: Warning Dangerous Cargo No visitors No Smoking No Open Lights (b)...

  15. 33 CFR 127.1113 - Warning signs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Waterfront Facilities Handling Liquefied Hazardous Gas Design and Construction § 127.1113 Warning signs. (a... section, bear the following text: Warning Dangerous Cargo No visitors No Smoking No Open Lights (b)...

  16. Few Americans Know Warning Signs of Stroke

    MedlinePLUS

    ... 155373.html Few Americans Know Warning Signs of Stroke New song can help people recall symptoms and ... people can't list any warning signs of stroke, research from the American Stroke Association shows. However, ...

  17. People-centred landslide early warning systems in the context of risk management

    NASA Astrophysics Data System (ADS)

    Haß, S.; Asch, K.; Fernandez-Steeger, T.; Arnhardt, C.

    2009-04-01

    In the current hazard research people-centred warning becomes more and more important, because different types of organizations and groups have to be involved in the warning process. This fact has to be taken into account when developing early warning systems. The effectiveness of early warning depends not only on technical capabilities but also on the preparedness of decision makers and their immediate response on how to act in case of emergency. Hence early warning systems have to be regarded in the context of an integrated and holistic risk management. Disaster Risk Reduction (DRR) measures include people-centred, timely and understandable warning. Further responsible authorities have to be identified in advance and standards for risk communication have to be established. Up to now, hazard and risk assessment for geohazards focuses on the development of inventory, susceptibility, hazard and risk maps. But often, especially in Europe, there are no institutional structures for managing geohazards and in addition there is a lack of an authority that is legally obliged to alarm on landslides at national or regional level. One of the main characteristics within the warning process for natural hazards e.g. in Germany is the split of responsibility between scientific authorities (wissenschaftliche Fachbehörde) and enforcement authorities (Vollzugsbehörde). The scientific authority provides the experts who define the methods and measures for monitoring and evaluate the hazard level. The main focus is the acquisition and evaluation of data and subsequently the distribution of information. The enforcement authority issues official warnings about dangerous natural phenomena. Hence the information chain in the context of early warning ranges over two different institutions, the forecast service and the warning service. But there doesn't exist a framework for warning processes in terms of landslides as yet. The concept for managing natural disasters is often reduced to hazard assessment and emergency response. Great importance is attached to the scientific understanding of hazards and protective structures, while analysis of socio-economic impacts and risk assessment are not considered enough. The reduction of vulnerability has to be taken into greater account. Also the information needs of different stakeholders have to be identified at an early stage and should be integrated in the development of early warning systems. The content of the warning message must be simple, understandable and should cover instructions on how to react. Further the timeliness of the messages has to be guarented. In this context the aim of the landslide monitoring and early warning system SLEWS (Sensor Based Landslide Early Warning System) is to integrate the above mentioned aspects of a holistic disaster and risk management. The technology of spatial data infrastructures and web services provides the use of multiple communication channels within an early warning system. Thus people-centred early warning messages and information about slope stability can be sent in nearly real-time. It has to be underlined that the technological information process is just one element of an effective warning system. Moreover the warning system has also to be considered as a social system and has to make allowance to socio-economic and gender aspects : «[...] Develop early warning systems that are people centered, in particular systems whose warnings are timely and understandable to those at risk, which take into account the demographic, gender, cultural and livelihood characteristics of the target audiences, including guidance on how to act upon warnings, and that support effective operations by disaster managers and other decision makers » (Hyogo Framework, 2005) References : UNITED NATIONS INTERNATIONAL STRATEGY FOR DISASTER REDUCTION SECRETARIAT (UNISDR) (2006): Developing early warning systems: a checklist, Third international conference on early warning (EWC III): from concept to action: 27-29 March 2006, Bonn, Germany. Geneva, Switzerland: International Strate

  18. 14 CFR 25.207 - Stall warning.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Stall warning. 25.207 Section 25.207 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Flight Stalls § 25.207 Stall warning. (a) Stall warning with sufficient margin to prevent...

  19. 30 CFR 57.14214 - Train warnings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Train warnings. 57.14214 Section 57.14214... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b)...

  20. 30 CFR 56.14214 - Train warnings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Train warnings. 56.14214 Section 56.14214... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b) When...

  1. 30 CFR 57.14214 - Train warnings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Train warnings. 57.14214 Section 57.14214... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b)...

  2. 30 CFR 57.14214 - Train warnings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Train warnings. 57.14214 Section 57.14214... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b)...

  3. 30 CFR 56.14214 - Train warnings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Train warnings. 56.14214 Section 56.14214... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b) When...

  4. 30 CFR 57.14214 - Train warnings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Train warnings. 57.14214 Section 57.14214... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b)...

  5. 30 CFR 57.14214 - Train warnings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Train warnings. 57.14214 Section 57.14214... Equipment Safety Practices and Operational Procedures § 57.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b)...

  6. 30 CFR 56.14214 - Train warnings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Train warnings. 56.14214 Section 56.14214... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b) When...

  7. 30 CFR 56.14214 - Train warnings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Train warnings. 56.14214 Section 56.14214... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b) When...

  8. 30 CFR 56.14214 - Train warnings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Train warnings. 56.14214 Section 56.14214... Safety Practices and Operational Procedures § 56.14214 Train warnings. A warning that is audible above the surrounding noise level shall be sounded— (a) Immediately prior to moving trains; (b) When...

  9. Warning Signs of Heart Failure

    MedlinePLUS

    Warning Signs of Heart Failure Updated:Sep 30,2015 By themselves, any one sign of heart failure may not be cause for alarm. But ... below you agree to the Terms and Conditions Heart Failure Questions to Ask Your Doctor Use these questions ...

  10. WARNING: Eclipse! chasing is addictive.!

    E-print Network

    Schneider, Glenn

    WARNING: Eclipse! chasing is addictive.! There is no cure.! center image by M. Druckmuller Dr to the memory of Prof. David Peck Todd (1855 ­ 1939) The Eclipse-Chaser's Eclipse-Chaser and inventor of Automatic Eclipse Photography and Radial Gradient (coronal) Imaging (and much more...) #12

  11. 77 FR 27591 - Labeling and Effectiveness Testing; Sunscreen Drug Products for Over-the-Counter Human Use; Delay...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-11

    ...The Food and Drug Administration (FDA) is delaying the compliance dates for the final rule for over-the-counter (OTC) sunscreen drug products that published in the Federal Register of June 17, 2011 (76 FR 35620). The final rule establishes labeling and effectiveness testing for certain OTC sunscreen products containing specified active ingredients and marketed without approved applications. It......

  12. 75 FR 9767 - Classification of Benzoyl Peroxide as Safe and Effective and Revision of Labeling to Drug Facts...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 333 RIN 0910--AG00...as Safe and Effective and Revision of Labeling to Drug Facts Format; Topical Acne Drug Products for Over-The-Counter Human Use;...

  13. What Contributes to the Split-Attention Effect? The Role of Text Segmentation, Picture Labelling, and Spatial Proximity

    ERIC Educational Resources Information Center

    Florax, Mareike; Ploetzner, Rolf

    2010-01-01

    In the split-attention effect spatial proximity is frequently considered to be pivotal. The transition from a spatially separated to a spatially integrated format not only involves changes in spatial proximity, but commonly necessitates text segmentation and picture labelling as well. In an experimental study, we investigated the influence of…

  14. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...Animal food containing or manufactured with a chlorofluorocarbon or other ozone-depleting substance. ...foods that contain or are manufactured with a chlorofluorocarbon or other ozone-depleting substance...

  15. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...Animal food containing or manufactured with a chlorofluorocarbon or other ozone-depleting substance. ...foods that contain or are manufactured with a chlorofluorocarbon or other ozone-depleting substance...

  16. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...Animal food containing or manufactured with a chlorofluorocarbon or other ozone-depleting substance. ...foods that contain or are manufactured with a chlorofluorocarbon or other ozone-depleting substance...

  17. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...Animal food containing or manufactured with a chlorofluorocarbon or other ozone-depleting substance. ...foods that contain or are manufactured with a chlorofluorocarbon or other ozone-depleting substance...

  18. 21 CFR 501.17 - Animal food labeling warning statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...Animal food containing or manufactured with a chlorofluorocarbon or other ozone-depleting substance. ...foods that contain or are manufactured with a chlorofluorocarbon or other ozone-depleting substance...

  19. Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling

    NASA Astrophysics Data System (ADS)

    Horák, Daniel; Babi?, Michal; Jendelová, Pavla; Herynek, Vít; Trchová, Miroslava; Likav?anová, Katarina; Kapcalová, Miroslava; Hájek, Milan; Syková, Eva

    2009-05-01

    Maghemite nanoparticles with various coatings were prepared by the coprecipitation method and characterized by transmission electron microscopy, dynamic light scattering and IR in terms of morphology, size, polydispersity and surface coating. The labeling efficiency and the viability of both rat and human mesenchymal stem cells labeled with Endorem ®, poly( L-lysine) (PLL)-modified Endorem ®, uncoated ?-Fe 2O 3, D-mannose-, PLL- or poly( N,N-dimethylacrylamide) (PDMAAm)-coated ?-Fe 2O 3 nanoparticles were compared. Coated ?-Fe 2O 3 nanoparticles labeled cells better than did Endorem ®. High relaxation rates and in vitro magnetic resonance imaging of cells labeled with coated nanoparticles showed clearly visible contrast compared with unlabeled cells or cells labeled with Endorem ®.

  20. The Emotional Impact and Ease of Recall of Warning Signs for Suicide: A Controlled Study

    ERIC Educational Resources Information Center

    Rudd, M. David; Mandrusiak, Michael; Joiner, Thomas E., Jr.; Berman, Alan L.; Van Orden, Kimberly A.; Hollar, Daniel

    2006-01-01

    In light of concerns about potential iatrogenic effects of information about suicide, in the current study we examined the emotional impact of reading a list of warning signs for suicide in comparison to comparable lists for heart attacks and diabetes. All participants read two sets of warning signs, with the experimental group reading the suicide…

  1. Licorice abuse: time to send a warning message

    PubMed Central

    Komarova, Irina; El-Ghonemi, Mohamed; Fathy, Ahmed; Rashad, Rania; Abdelmalak, Hany D.; Yerramadha, Muralidhar Reddy; Ali, Yaseen; Helal, Engy; Camporesi, Enrico M.

    2012-01-01

    Licorice extract has always been recognized as a sweetener and a thirst quencher. Its nutritive value is overrated by many who consume significant amounts and are prone to complications. Glycyrrhetic acid, the active metabolite in licorice, inhibits the enzyme 11-ß-hydroxysteroid dehydrogenase enzyme type 2 with a resultant cortisol-induced mineralocorticoid effect and the tendency towards the elevation of sodium and reduction of potassium levels. This aldosterone-like action is the fundamental basis for understanding its health benefits and the wide spectrum of adverse effects. Herein, we present a comprehensive review of licorice along with the reported complications related to excess intake. Despite its apparent use in a few clinical scenarios, the daily consumption of licorice is never justified because its benefits are minor compared to the adverse outcomes of chronic consumption. The review highlights the importance of investigating the dietary habits and herbal remedies which are being used worldwide on cultural and habitual bases rather than reliable scientific evidence. Licorice is a US Food and Drug Administration (FDA) approved food supplement used in many products without precise regulations to prevent toxicity. Increased awareness among the public is required through TV commercials, newspapers, internet sites, magazines and product labels regarding the upper limit of ingestion and health hazards associated with excess intake. We hope that this review will serve as a warning message that should be transmitted from physicians to patients to avoid excessive licorice intake as well as a message to the FDA to start regulating the use of this substance. PMID:23185686

  2. The Financial Benefit of Early Flood Warnings in Europe

    NASA Astrophysics Data System (ADS)

    Pappenberger, Florian; Cloke, Hannah L.; Wetterhall, Fredrik; Parker, Dennis J.; Richardson, David; Thielen, Jutta

    2015-04-01

    Effective disaster risk management relies on science based solutions to close the gap between prevention and preparedness measures. The outcome of consultations on the UNIDSR post-2015 framework for disaster risk reduction highlight the need for cross-border early warning systems to strengthen the preparedness phases of disaster risk management in order to save people's lives and property and reduce the overall impact of severe events. In particular, continental and global scale flood forecasting systems provide vital information to various decision makers with which early warnings of floods can be made. Here the potential monetary benefits of early flood warnings using the example of the European Flood Awareness System (EFAS) are calculated based on pan-European Flood damage data and calculations of potential flood damage reductions. The benefits are of the order of 400 Euro for every 1 Euro invested. Because of the uncertainties which accompany the calculation, a large sensitivity analysis is performed in order to develop an envelope of possible financial benefits. Current EFAS system skill is compared against perfect forecasts to demonstrate the importance of further improving the skill of the forecasts. Improving the response to warnings is also essential in reaping the benefits of flood early warnings.

  3. Dynamic Vibrotactile Signals for Forward Collision Avoidance Warning Systems

    PubMed Central

    Meng, Fanxing; Gray, Rob; Ho, Cristy; Ahtamad, Mujthaba

    2015-01-01

    Objective: Four experiments were conducted in order to assess the effectiveness of dynamic vibrotactile collision-warning signals in potentially enhancing safe driving. Background: Auditory neuroscience research has demonstrated that auditory signals that move toward a person are more salient than those that move away. If this looming effect were found to extend to the tactile modality, then it could be utilized in the context of in-car warning signal design. Method: The effectiveness of various vibrotactile warning signals was assessed using a simulated car-following task. The vibrotactile warning signals consisted of dynamic toward-/away-from-torso cues (Experiment 1), dynamic versus static vibrotactile cues (Experiment 2), looming-intensity- and constant-intensity-toward-torso cues (Experiment 3), and static cues presented on the hands or on the waist, having either a low or high vibration intensity (Experiment 4). Results: Braking reaction times (BRTs) were significantly faster for toward-torso as compared to away-from-torso cues (Experiments 1 and 2) and static cues (Experiment 2). This difference could not have been attributed to differential responses to signals delivered to different body parts (i.e., the waist vs. hands; Experiment 4). Embedding a looming-intensity signal into the toward-torso signal did not result in any additional BRT benefits (Experiment 3). Conclusion: Dynamic vibrotactile cues that feel as though they are approaching the torso can be used to communicate information concerning external events, resulting in a significantly faster reaction time to potential collisions. Application: Dynamic vibrotactile warning signals that move toward the body offer great potential for the design of future in-car collision-warning system. PMID:25850161

  4. Effects of organizational scheme and labeling on task performance in product-centered and user-centered retail Web sites.

    PubMed

    Resnick, Marc L; Sanchez, Julian

    2004-01-01

    As companies increase the quantity of information they provide through their Web sites, it is critical that content is structured with an appropriate architecture. However, resource constraints often limit the ability of companies to apply all Web design principles completely. This study quantifies the effects of two major information architecture principles in a controlled study that isolates the incremental effects of organizational scheme and labeling on user performance and satisfaction. Sixty participants with a wide range of Internet and on-line shopping experience were recruited to complete a series of shopping tasks on a prototype retail shopping Web site. User-centered labels provided a significant benefit in performance and satisfaction over labels obtained through company-centered methods. User-centered organization did not result in improved performance except when the label quality was poor. Significant interactions suggest specific guidelines for allocating resources in Web site design. Applications of this research include the design of Web sites for any commercial application, particularly E-commerce. PMID:15151158

  5. Global warning, global warming

    SciTech Connect

    Benarde, M.A. )

    1992-01-01

    This book provides insights into the formidable array of issues which, in a warmer world, could impinge upon every facet of readers lives. It examines climatic change and long-term implications of global warming for the ecosystem. Topics include the ozone layer and how it works; the greenhouse effect; the dangers of imbalance and its effects on human and animal life; disruptions to the basic ecology of the planet; and the real scientific evidence for and against aberrant climatic shifts. The author also examines workable social and political programs and changes that must be instituted to avoid ecological disaster.

  6. 9 CFR 112.2 - Final container label, carton label, and enclosure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...C. or stated as not over 45 °F. or 7 °C. (5) Full instructions for the proper use of the product, including vaccination schedules, warnings, cautions, and the like: Provided, That in the case of very small final container labels or...

  7. 9 CFR 112.2 - Final container label, carton label, and enclosure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...C. or stated as not over 45 °F. or 7 °C. (5) Full instructions for the proper use of the product, including vaccination schedules, warnings, cautions, and the like: Provided, That in the case of very small final container labels or...

  8. 9 CFR 112.2 - Final container label, carton label, and enclosure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS PACKAGING AND LABELING...product contains viable or dangerous organisms or viruses, a warning to “Burn this container...antigenic fraction is to be used instead of a water diluent for one or more...

  9. 9 CFR 112.2 - Final container label, carton label, and enclosure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS PACKAGING AND LABELING...product contains viable or dangerous organisms or viruses, a warning to “Burn this container...antigenic fraction is to be used instead of a water diluent for one or more...

  10. 9 CFR 112.2 - Final container label, carton label, and enclosure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS PACKAGING AND LABELING...product contains viable or dangerous organisms or viruses, a warning to “Burn this container...antigenic fraction is to be used instead of a water diluent for one or more...

  11. Kinetic isotope effects significantly influence intracellular metabolite [superscript 13]C labeling patterns and flux determination

    E-print Network

    Stephanopoulos, Gregory

    Rigorous mathematical modeling of carbon-labeling experiments allows estimation of fluxes through the pathways of central carbon metabolism, yielding powerful information for basic scientific studies as well as for a wide ...

  12. Label-free field-effect-based single-molecule detection of DNA hybridization kinetics

    PubMed Central

    Sorgenfrei, Sebastian; Chiu, Chien-yang; Gonzalez, Ruben L.; Yu, Young-Jun; Kim, Philip; Nuckolls, Colin; Shepard, Kenneth L.

    2013-01-01

    Probing biomolecules at the single-molecule level can provide useful information about molecular interactions, kinetics and motions that is usually hidden in ensemble measurements. Techniques with improved sensitivity and time resolution are required to explore fast biomolecular dynamics. Here, we report the first observation of DNA hybridization at the single-molecule level using a carbon nanotube field-effect transistor. By covalently attaching a single-stranded probe DNA sequence to a point defect in a carbon nanotube, we are able to measure two-level fluctuations in the nanotube conductance due to reversible hybridizing and melting of a complementary DNA target. The kinetics are studied as a function of temperature, allowing the measurement of rate constants, melting curves and activation energies for different sequences and target concentrations. The kinetics show non-Arrhenius behavior, in agreement with DNA hybridization experiments using fluorescence correlation spectroscopy. This technique is label-free and has the potential for studying single-molecule dynamics at sub-microsecond time-scales. PMID:21258331

  13. Supplementing Menu Labeling With Calorie Recommendations to Test for Facilitation Effects

    PubMed Central

    Wisdom, Jessica; Wansink, Brian; Loewenstein, George

    2013-01-01

    Objectives. We examined the effect on food purchases of adding recommended calorie intake per day or per meal to the mandated calorie information posted on chain restaurant menus. Methods. Before and after New York City implemented calorie posting on chain restaurant menus in 2008, we provided daily, per-meal, or no calorie recommendations to randomized subsets of adult lunchtime customers (n?=?1121) entering 2 McDonald’s restaurants, in Manhattan and Brooklyn, and collected receipts and survey responses as they exited. In linear and logistic regressions, with adjustment for gender, race, age, and day, we tested for simple differences in calories consumed and interactions between variables. Results. Posting calorie benchmarks had no direct impact, nor did it moderate the impact of calorie labels on food purchases. The recommendation appeared to promote a slight increase in calorie intake, attributable to increased purchases of higher-calorie entrées. Conclusions. These results do not support the introduction of calorie recommendations as a means of enhancing the impact of posted calorie information or reducing the contribution of restaurant dining to the obesity epidemic. PMID:23865657

  14. 14 CFR 23.703 - Takeoff warning system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AIRWORTHINESS STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Design and Construction... revising the introductory text and adding a new paragraph (c), effective Jan. 31, 2012. For the convenience of the user, the added and revised text is set forth as follows: § 23.703 Takeoff warning system....

  15. The effect of cryoprotection on the use of PLGA encapsulated iron oxide nanoparticles for magnetic cell labeling

    NASA Astrophysics Data System (ADS)

    Tang, Kevin S.; Hashmi, Sarah M.; Shapiro, Erik M.

    2013-03-01

    Magnetic PLGA nanoparticles are a significant advancement in the quest to translate MRI-based cell tracking to the clinic. The benefits of these types of particles are that they encapsulate large amounts of iron oxide nanocrystals within an FDA-approved polymer matrix, combining the best aspects of inert micron-sized iron oxide particles, or MPIOs, and biodegradable small particles of iron oxide, or SPIOs. Practically, PLGA nanoparticle fabrication and storage requires some form of cryoprotectant to both protect the particle during freeze drying and to promote resuspension. While this is a commonly employed procedure in the fabrication of drug loaded PLGA nanoparticles, it has yet to be investigated for magnetic particles and what effect this might have on internalization of magnetic particles. As such, in this study, magnetic PLGA nanoparticles were fabricated with various concentrations of two common cryoprotectants, dextrose and sucrose, and analyzed for their ability to magnetically label cells. It was found that cryoprotection with either sugar significantly enhanced the ability to resuspend nanoparticles without aggregation. Magnetic cell labeling was impacted by sugar concentration, with higher sugar concentrations used during freeze drying more significantly reducing magnetic cell labeling than lower concentrations. These studies suggest that cryoprotection with 1% dextrose is an optimal compromise that preserves monodispersity following resuspension and high magnetic cell labeling.

  16. Methane production in ruminants: Its effect on the doubly labeled water method

    SciTech Connect

    Midwood, A.J.; Haggarty, P.; McGaw, B.A.; Robinson, J.J. )

    1989-12-01

    The doubly labeled water (DLW) technique for measuring CO2 production (rCO2) in free-living animals requires an assessment of the elimination of both 2H and 18O from the body over a long period of time. To calculate rCO2, it is necessary to calculate water turnover (rH2O) from the 2H flux rate. In ruminant animals, the accuracy of this calculation is affected by the loss of 2H in methane. We have quantified the effect of methane production (rCH4) on the 2H flux rate, determined in four sheep given 2H2O. The methane produced was depleted in 2H relative to the urine. A relationship between the enrichment of the methane and urine was established. The ratio of urine to methane enrichment was found on average to be 0.6536, and this value was unaffected by the level of rCH4 but showed some dependence on the absolute concentration of 2H in urine. For this reason, the ratio value obtained from four sheep not given 2H2O was different, a mean of 0.6886 was measured, this ratio was unaffected by changes in the diet supplied to the animals. Computer modeling was used to illustrate the dependence of the isotopically derived value for rCO2 on not only rCH4 but also the magnitude of rCO2 itself. The effect of rCH4 on the DLW method can be predicted from the observed ratio of rCO2 to rCH4 and the value of 0.6536 obtained for the ratio of methane to urine enrichment. With the use of data from several studies at this Institute, a limited range of 10 to 20 was found for rCO2/rCH4 in animals fed at or above maintenance.

  17. Implementing drought early warning systems: policy lessons and future needs

    NASA Astrophysics Data System (ADS)

    Iglesias, Ana; Werner, Micha; Maia, Rodrigo; Garrote, Luis; Nyabeze, Washington

    2014-05-01

    Drought forecasting and Warning provides the potential of reducing impacts to society due to drought events. The implementation of effective drought forecasting and warning, however, requires not only science to support reliable forecasting, but also adequate policy and societal response. Here we propose a protocol to develop drought forecasting and early warning based in the international cooperation of African and European institutions in the DEWFORA project (EC, 7th Framework Programme). The protocol includes four major phases that address the scientific knowledge and the social capacity to use the knowledge: (a) What is the science available? Evaluating how signs of impending drought can be detected and predicted, defining risk levels, and analysing of the signs of drought in an integrated vulnerability approach. (b) What are the societal capacities? In this the institutional framework that enables policy development is evaluated. The protocol gathers information on vulnerability and pending hazard in advance so that early warnings can be declared at sufficient lead time and drought mitigation planning can be implemented at an early stage. (c) How can science be translated into policy? Linking science indicators into the actions/interventions that society needs to implement, and evaluating how policy is implemented. Key limitations to planning for drought are the social capacities to implement early warning systems. Vulnerability assessment contributes to identify these limitations and therefore provides crucial information to policy development. Based on the assessment of vulnerability we suggest thresholds for management actions to respond to drought forecasts and link predictive indicators to relevant potential mitigation strategies. Vulnerability assessment is crucial to identify relief, coping and management responses that contribute to a more resilient society. (d) How can society benefit from the forecast? Evaluating how information is provided to potentially affected groups, and how mitigation strategies can be taken in response. This paper presents an outline of the protocol that was developed in the DEWFORA project, outlining the complementary roles of science, policy and societal uptake in effective drought forecasting and warning. A consensus on the need to emphasise the social component of early warning was reached when testing the DEWFORA early warning system protocol among experts from 18 countries.

  18. Effectiveness and Duration of Effect of Open-Label Lisdexamfetamine Dimesylate in Adults With ADHD.

    PubMed

    Adler, Lenard A; Lynch, Lauren R; Shaw, David M; Wallace, Samantha P; O'Donnell, Katherine E; Ciranni, Michael A; Briggie, Alexis M; Faraone, Stephen V

    2013-05-01

    Objectives: (a) Evaluate the efficacy and duration of effect of lisdexamfetamine dimesylate (LDX) in adult ADHD. (b) Assess the reliability and validity of the Adult ADHD Medication Smoothness of Effect Scale (AMSES) and Adult ADHD Medication Rebound Scale (AMRS). Method: Adults (N = 40) with ADHD were treated with LDX for up to 12 weeks. The primary efficacy measure was the ADHD Rating Scale (ADHD-RS). The psychometric properties of the AMSES and AMRS are analyzed and compared with the ADHD-RS, ADHD Self-Report Scale (ASRS) v1.1 Symptom Checklist, and Time-Sensitive ADHD Symptom Scale (TASS). Results: ADHD-RS scores were significantly improved with LDX. The AMSES and AMRS had high internal consistency and were correlated with the ADHD-RS, ASRS v1.1 Symptom Checklist, and TASS. Conclusion: LDX is effective in treating adult ADHD and has a smooth drug effect throughout the day with limited symptom rebound. The AMSES and AMRS are valid and reliable measures. (J. of Att. Dis. 2013; XX(X) 1-XX). PMID:23657761

  19. Effect of Thuya occidentalis on the labeling of red blood cells and plasma proteins with technetium-99m.

    PubMed Central

    Oliveira, J. F.; Braga, A. C.; Avila, A. S.; Fonseca, L. M.; Gutfilen, B.; Bernardo-Filho, M.

    1996-01-01

    Thuya occidentalis is used in popular medicine in the treatment of condyloma and has antibacterial action. Red blood cells (RBC) labeled with technetium-99m (99mTc) are used for several evaluations in nuclear medicine. This labeling depends on a reducing agent, usually stannous ion. Any drug which alters the labeling of the tracer could be expected to modify the disposition of the radiopharmaceutical. We have evaluated the influence of T. occidentalis extract on the labeling of RBC and plasma proteins with 99mTc. Blood was withdrawn and incubated with T. occidentalis (0.25; 2.5; 20.5; and 34.1 percent v/v). Stannous chloride (1.2 micrograms/ml) was added and then 99mTc was added. Plasma (P) and blood cells (BC) were isolated, also precipitated with trichloroacetic acid and soluble (SF) and insoluble fractions (IF) separated. The analysis of the results shows that there is a decrease in radioactivity (from 97.64 to 75.89 percent) in BC with 34.1 percent of the drug. In the labeling process of RBC with 99mTc, the stannous and pertechnetate ions pass through the membrane, so we suggest that the T. occidentalis effect can be explained (i) by an inhibition of the transport of these ions, (ii) by damage in membrane, (iii) by competition with the cited ions for the same binding sites, or (iv) by possible generation of reactive oxygen species that could oxidize the stannous ion. PMID:9436292

  20. The effect of circulating antigen and radiolabel stability on the biodistribution of an indium labelled antibody.

    PubMed Central

    Davidson, B. R.; Babich, J.; Young, H.; Waddington, W.; Clarke, G.; Short, M.; Boulos, P.; Styles, J.; Dean, C.

    1991-01-01

    This study has investigated two of the main problems with radiolabelled antibody imaging, the formation of circulating immune complexes (I.C.) and the non specific binding of radiolabel to the antibody molecule. Patients undergoing immunoscintigraphy with 111In labelled monoclonal antibody ICR2 were divided into three groups who received either the radiolabelled antibody alone (control, n = 12), the radiolabelled antibody which was incubated with the chelating agent diethylene triamine pentacetic acid (DTPA) prior to size exclusion chromatography (n = 6) or whose injectate was treated with DTPA and cold MAb administered intravenously prior to radiolabelled MAb administration (n = 6). Radiolabelled antibody uptake in abdominal organs was measured by region of interest analysis using a gamma camera with online computer and that in tumour and normal tissues by gamma well counting of biopsies. Circulating antigen and immune complex was measured by high pressure liquid chromatography (HPLC). The sensitivity of tumour imaging and the tumour uptake of radiolabelled antibody was not significantly different between the groups. Patients with high circulating antigen levels developed high levels of circulating immune complex but also had high tumour uptakes of radiolabelled antibody. Administration of cold MAb increased the splenic, but did not effect the tumour uptake of radiolabelled antibody and only minimally reduced levels of circulating immune complex. Chelate administration reduced the urinary excretion of radioactivity but increased the liver uptake of radioactivity. These results have shown that successful antibody imaging can be carried out despite high levels of circulating antigen, that large doses of unlabelled antibody are required to prevent immune complex formation and that removal of non specifically bound 111In does not reduce the liver uptake of radioactivity. PMID:1931605

  1. Effects of laser labeling on the quality of citrus fruit during storage

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Etching the required information on fruit and vegetables is an alternative means to label produce. Low energy CO2 laser etches the surface showing the contrasting underlying layer. These etched surfaces can promote water loss and potentially allow for pathogen entry. Studies were conducted to measur...

  2. 77 FR 72868 - Compliance Guidance for Small Business Entities on Labeling and Effectiveness Testing; Sunscreen...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ...51, Rm. 2201, Silver Spring, MD 20993-0002. Send one self-addressed adhesive label to assist that office in processing...Rockville, MD 20852. FOR FURTHER INFORMATION CONTACT: Reynold Tan, Center for Drug Evaluation and Research, Food and Drug...

  3. Speaking the Same Language: The Cooperative Effects of Labeling in the Prisoner's Dilemma

    ERIC Educational Resources Information Center

    Zhong, Chen-Bo; Loewenstein, Jeffrey; Murnighan, J. Keith

    2007-01-01

    The long history of experimental research on the prisoner's dilemma (PD) has primarily used a methodology that eliminates cues to participants. Researchers, however, have interpreted participants' choices as cooperative or competitive. The authors' research shows that giving participants researchers' interpretive labels of the game, the choices,…

  4. Effects of laser labeling on the quality of tangerines during storage

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Etching the required information on fruit and vegetables is an alternative means to label produce. Low energy CO2 laser etches the surface showing the contrasting underlying layer. These etched surfaces can promote water loss and potentially allow for pathogen entry. Studies were conducted to measur...

  5. Flow ensemble prediction for flash flood warnings at ungauged basins

    NASA Astrophysics Data System (ADS)

    Demargne, Julie; Javelle, Pierre; Organde, Didier; Caseri, Angelica; Ramos, Maria-Helena; de Saint Aubin, Céline; Jurdy, Nicolas

    2015-04-01

    Flash floods, which are typically triggered by severe rainfall events, are difficult to monitor and predict at the spatial and temporal scales of interest due to large meteorological and hydrologic uncertainties. In particular, uncertainties in quantitative precipitation forecasts (QPF) and quantitative precipitation estimates (QPE) need to be taken into account to provide skillful flash flood warnings with increased warning lead time. In France, the AIGA discharge-threshold flood warning system is currently being enhanced to ingest high-resolution ensemble QPFs from convection-permitting numerical weather prediction (NWP) models, as well as probabilistic QPEs, to improve flash flood warnings for small-to-medium (from 10 to 1000 km²) ungauged basins. The current deterministic AIGA system is operational in the South of France since 2005. It ingests the operational radar-gauge QPE grids from Météo-France to run a simplified hourly distributed hydrologic model at a 1-km² resolution every 15 minutes (Javelle et al. 2014). This produces real-time peak discharge estimates along the river network, which are subsequently compared to regionalized flood frequency estimates of given return periods. Warnings are then provided to the French national hydro-meteorological and flood forecasting centre (SCHAPI) and regional flood forecasting offices, based on the estimated severity of ongoing events. The calibration and regionalization of the hydrologic model has been recently enhanced to implement an operational flash flood warning system for the entire French territory. To quantify the QPF uncertainty, the COSMO-DE-EPS rainfall ensembles from the Deutscher Wetterdienst (20 members at a 2.8-km resolution for a lead time of 21 hours), which are available on the North-eastern part of France, were ingested in the hydrologic model of the AIGA system. Streamflow ensembles were produced and probabilistic flash flood warnings were derived for the Meuse and Moselle river basins and for significant events of the 2010-2013 period. The evaluation showed significant improvements in terms of flash flood event detection and effective warning lead-time, compared to warnings from the current AIGA setup (without any future precipitation). Various verification metrics (e.g., Relative Mean Error, Continuous Rank Probability Skill Score) show the skill of ensemble precipitation and flow forecasts compared to single-valued persistency benchmarks. In addition to propagating the QPF uncertainty to streamflow forecasts, we discuss how to account for other sources of forecast uncertainty, including precipitation observational uncertainty (Caseri et al. 2014) and hydrologic uncertainties. Planned enhancements include ingesting other probabilistic nowcast and NWP products from Météo-France's convection-permitting AROME model, as well as developing comprehensive observational and post-event damage database to determine decision-relevant thresholds for flood magnitude and probability. Caseri, A., Javelle, P., Ramos, M.H., Leblois, E., 2014. Generating precipitation ensembles for flood alert and risk management. Journal of Flood Risk Management (submitted). Javelle, P., Demargne, J., Defrance, D., Arnaud, P., 2014. Evaluating flash flood warnings at ungauged locations using post-event surveys: a case study with the AIGA warning system. Hydrological Sciences Journal. doi: 10.1080/02626667.2014.923970

  6. Warning Signs of Heart Attack, Stroke and Cardiac Arrest

    MedlinePLUS

    ... a Heart Attack WARNING SIGNS OF HEART ATTACK, STROKE & CARDIAC ARREST HEART ATTACK WARNING SIGNS CHEST DISCOMFORT ... nausea or lightheadedness. Learn more about heart attack STROKE WARNING SIGNS Spot a stroke F.A.S.T.: - ...

  7. CISN ShakeAlert: Accounting for site amplification effects and quantifying time and spatial dependence of uncertainty estimates in the Virtual Seismologist earthquake early warning algorithm

    NASA Astrophysics Data System (ADS)

    Caprio, M.; Cua, G. B.; Wiemer, S.; Fischer, M.; Heaton, T. H.; CISN EEW Team

    2011-12-01

    The Virtual Seismologist (VS) earthquake early warning (EEW) algorithm is one of 3 EEW approaches being incorporated into the California Integrated Seismic Network (CISN) ShakeAlert system, a prototype EEW system being tested in real-time in California. The VS algorithm, implemented by the Swiss Seismological Service at ETH Zurich, is a Bayesian approach to EEW, wherein the most probable source estimate at any given time is a combination of contributions from a likehihood function that evolves in response to incoming data from the on-going earthquake, and selected prior information, which can include factors such as network topology, the Gutenberg-Richter relationship or previously observed seismicity. The VS codes have been running in real-time at the Southern California Seismic Network (SCSN) since July 2008, and at the Northern California Seismic Network (NCSN) since February 2009. With the aim of improving the convergence of real-time VS magnitude estimates to network magnitudes, we evaluate various empirical and Vs30-based approaches to accounting for site amplification. Empirical station corrections for SCSN stations are derived from M>3.0 events from 2005 through 2009. We evaluate the performance of the various approaches using an independent 2010 dataset. In addition, we analyze real-time VS performance from 2008 to the present to quantify the time and spatial dependence of VS uncertainty estimates. We also summarize real-time VS performance for significant 2011 events in California. Improved magnitude and uncertainty estimates potentially increase the utility of EEW information for end-users, particularly those intending to automate damage-mitigating actions based on real-time information.

  8. Scientific and public responses to the ongoing volcanic crisis at Popocatépetl Volcano, Mexico: Importance of an effective hazards-warning system

    USGS Publications Warehouse

    de la Cruz-Reyna, Servando; Tilling, Robert I.

    2008-01-01

    Volcanic eruptions and other potentially hazardous natural phenomena occur independently of any human actions. However, such phenomena can cause disasters when a society fails to foresee the hazardous manifestations and adopt adequate measures to reduce its vulnerability. One of the causes of such a failure is the lack of a consistent perception of the changing hazards posed by an ongoing eruption, i.e., with members of the scientific community, the Civil Protection authorities and the general public having diverging notions about what is occurring and what may happen. The problem of attaining a perception of risk as uniform as possible in a population measured in millions during an evolving eruption requires searching for communication tools that can describe—as simply as possible—the relations between the level of threat posed by the volcano, and the level of response of the authorities and the public. The hazards-warning system adopted at Popocatépetl Volcano, called the Volcanic Traffic Light Alert System(VTLAS), is a basic communications protocol that translates volcano threat into seven levels of preparedness for the emergency-management authorities, but only three levels of alert for the public (color coded green–yellow–red). The changing status of the volcano threat is represented as the most likely scenarios according to the opinions of an official scientific committee analyzing all available data. The implementation of the VTLAS was intended to reduce the possibility of ambiguous interpretations of intermediate levels by the endangered population. Although the VTLAS is imperfect and has not solved all problems involved in mass communication and decision-making during a volcanic crisis, it marks a significant advance in the management of volcanic crises in Mexico.

  9. Scientific and public responses to the ongoing volcanic crisis at Popocatépetl Volcano, Mexico: Importance of an effective hazards-warning system

    NASA Astrophysics Data System (ADS)

    De la Cruz-Reyna, Servando; Tilling, Robert I.

    2008-02-01

    Volcanic eruptions and other potentially hazardous natural phenomena occur independently of any human actions. However, such phenomena can cause disasters when a society fails to foresee the hazardous manifestations and adopt adequate measures to reduce its vulnerability. One of the causes of such a failure is the lack of a consistent perception of the changing hazards posed by an ongoing eruption, i.e., with members of the scientific community, the Civil Protection authorities and the general public having diverging notions about what is occurring and what may happen. The problem of attaining a perception of risk as uniform as possible in a population measured in millions during an evolving eruption requires searching for communication tools that can describe—as simply as possible—the relations between the level of threat posed by the volcano, and the level of response of the authorities and the public. The hazards-warning system adopted at Popocatépetl Volcano, called the Volcanic Traffic Light Alert System (VTLAS), is a basic communications protocol that translates volcano threat into seven levels of preparedness for the emergency-management authorities, but only three levels of alert for the public (color coded green-yellow-red). The changing status of the volcano threat is represented as the most likely scenarios according to the opinions of an official scientific committee analyzing all available data. The implementation of the VTLAS was intended to reduce the possibility of ambiguous interpretations of intermediate levels by the endangered population. Although the VTLAS is imperfect and has not solved all problems involved in mass communication and decision-making during a volcanic crisis, it marks a significant advance in the management of volcanic crises in Mexico.

  10. 77 FR 6785 - Proposed Information Collection; Comment Request; Feedback Survey for Annual Tsunami Warning...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... exceed seven days. This will be a Web-based survey and will allow for efficient collection of information regarding the effectiveness of the Tsunami Warning System. II. Method of Collection A Web-based survey...

  11. 49 CFR 229.113 - Warning notice.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Steam Generators § 229.113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam...

  12. 49 CFR 229.113 - Warning notice.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Steam Generators § 229.113 Warning notice. Whenever any steam generator has been shut down because of defects, a distinctive warning notice giving reasons for the shut-down shall be conspicuously attached near the steam...

  13. 21 CFR 1141.10 - Required warnings.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... warning shall be in the English language, except that: (i) In the case of an advertisement that appears in a non-English publication, the text in the required warning shall appear in the predominant language of the publication whether or not the advertisement is in English; and (ii) In the case of...

  14. Urban Flood Warning Systems using Radar Technologies

    NASA Astrophysics Data System (ADS)

    Fang, N.; Bedient, P. B.

    2013-12-01

    There have been an increasing number of urban areas that rely on weather radars to provide accurate precipitation information for flood warning purposes. As non-structural tools, radar-based flood warning systems can provide accurate and timely warnings to the public and private entities in urban areas that are prone to flash floods. The wider spatial and temporal coverage from radar increases flood warning lead-time when compared to rain and stream gages alone. The Third Generation Rice and Texas Medical Center (TMC) Flood Alert System (FAS3) has been delivering warning information with 2 to 3 hours of lead time and a R2 value of 93% to facility personnel in a readily understood format for more than 50 events in the past 15 years. The current FAS utilizes NEXRAD Level II radar rainfall data coupled with a real-time hydrologic model (RTHEC-1) to deliver warning information. The system has a user-friendly dashboard to provide rainfall maps, Google Maps based inundation maps, hydrologic predictions, and real-time monitoring at the bayou. This paper will evaluate its reliable performance during the recent events occurring in 2012 and 2013 and the development of a similar radar-based flood warning system for the City of Sugar Land, Texas. Having a significant role in the communication of flood information, FAS marks an important step towards the establishment of an operational and reliable flood warning system for flood-prone urban areas.

  15. Comprehension of Warnings and Resulting Attitudes.

    ERIC Educational Resources Information Center

    Lepkowska-White, Elzbieta; Parsons, Amy L.

    2001-01-01

    A study of 61 adults with at least a bachelor's degree and 44 high school dropouts showed that the latter perceived products with simply worded warnings as safer than those with difficult vocabulary. College-educated adults had more negative attitudes toward warnings with difficult words despite equal comprehension of both. (Contains 39…

  16. Nutrition Labeling

    NASA Astrophysics Data System (ADS)

    Metzger, Lloyd E.

    Nutrition labeling regulations differ in countries around the world. The focus of this chapter is on nutrition labeling regulations in the USA, as specified by the Food and Drug Administration (FDA) and the Food Safety and Inspection Service (FSIS) of the United States Department of Agriculture (USDA). A major reason for analyzing the chemical components of foods in the USA is nutrition labeling regulations. Nutrition label information is not only legally required in many countries, but also is of increasing importance to consumers as they focus more on health and wellness.

  17. Evaluation of an experimental central warning system with a synthesized voice component.

    PubMed

    Wheale, J L

    1983-06-01

    The experiment monitored the use of an experimental central warning system by experienced pilots. The warning system incorporated audio warnings, voice messages, and panel legends. The voice messages were produced by a Votrax synthesizer. Warning responses were assessed during a realistic flying task. Audio warnings produced significantly faster responses than panel legends or voice messages. Voice messages and audio warnings had a greater distracting effect on subjects' responses than panel legends. Workload level did not affect response to either the voice or audio warnings but responses to panel legends did lengthen significantly at high levels of workload. The Votrax voice messages were disliked by the pilots who adopted a strategy of cross-referring to panel legends upon hearing the attention-getting sound which preceded the voice messages because they had difficulty understanding the Votrax messages. The results suggest that Votrax voice messages may only augment the noise level of the flight deck and could effectively be replaced with an attention-getting sound and panel legend. It is also suggested that crew response to synthetic voice messages which can be understood on first presentation will be more positive than their response to Votrax messages. PMID:6192803

  18. Integrating Automobile Multiple Intelligent Warning Systems: Performance and Policy

    E-print Network

    Cummings, Mary "Missy"

    Integrating Automobile Multiple Intelligent Warning Systems: Performance and Policy Implications and Policy Program #12;2 #12;3 Integrating Automobile Multiple Intelligent Warning Systems: Performance

  19. Graphic gambling warnings: how they affect emotions, cognitive responses and attitude change.

    PubMed

    Muñoz, Yaromir; Chebat, Jean-Charles; Borges, Adilson

    2013-09-01

    The present study focuses on the effects of graphic warnings related to excessive gambling. It is based upon a theoretical model derived from both the Protection Motivation Theory (PMT) and the Elaboration Likelihood Model (ELM). We focus on video lottery terminal (VLT), one of the most hazardous format in the gaming industry. Our cohort consisted of 103 actual gamblers who reported previous gambling activity on VLT's on a regular basis. We assess the effectiveness of graphic warnings vs. text-only warnings and the effectiveness of two major arguments (i.e., family vs. financial disruption). A 2 × 2 factorial design was used to test the direct and combined effects of two variables (i.e., warning content and presence vs. absence of a graphic). It was found that the presence of a graphic enhances both cognitive appraisal and fear, and has positive effects on the Depth of Information Processing. In addition, graphic content combined with family disruptions is more effective for changing attitudes and complying with the warning than other combinations of the manipulated variables. It is proposed that ELM and PMT complement each other to explain the effects of warnings. Theoretical and practical implications are discussed. PMID:22648580

  20. 21 CFR 201.66 - Format and content requirements for over-the-counter (OTC) drug product labeling.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... subheading “Dosage warning:” (H) Sexually transmitted diseases (STDs) warning for vaginal contraceptive and... subheading “Sexually transmitted diseases (STDs) alert:” (iii) “Do not use” , followed by all... envelope as a “Request for Exemption from 21 CFR 201.66 (OTC Labeling Format)” and shall be directed...

  1. Effects of lutein and cholesterol on alkyl chain bending in lipid bilayers: a pulse electron spin resonance spin labeling study.

    PubMed Central

    Yin, J J; Subczynski, W K

    1996-01-01

    A short pulse saturation recovery electron spin resonance technique has been used to study the effects of polar carotenoid-lutein and cholesterol on interactions of 14N:15N stearic acid spin-label pairs in fluid-phase phosphatidylcholine (PC) membranes. Bimolecular collisions for pairs consisting of various combinations of [14N]-16-, [14N]-10-, [14N]-7-, or [14N]-5-doxylstearate and [15N]-16-doxylstearate in dimyristoyl-PC (DMPC) or egg yolk PC (EYPC) membranes were measured at 27 degrees C. In the absence and presence of lutein or cholesterol for both lipid systems, the collision rates were ordered as 16:5 < 16:7 < 16:10 < 16:16. For all spin-label pairs studied, interaction frequencies were greater in DMPC than in EYPC. Polar carotenoid-lutein reduces the collision frequency for all spin-label pairs, whereas cholesterol reduces the collision frequency for 16:5 and 16:7 pairs and increases the collision frequency in the membrane center for 16:10 and 16:16 pairs. The presence of unsaturated alkyl chains greatly reduces the effect of lutein but magnifies the effect of cholesterol in the membrane center. The observed differences in the effects of these modifiers on alkyl chain bending result from differences in the structure of cholesterol and polar carotenoid and from their different localization within the lipid bilayer membrane. These studies further confirm the occurrence of vertical fluctuations of alkyl chain ends toward the bilayer surface. PMID:8842221

  2. A communication model for interlinking national tsunami early warning systems

    NASA Astrophysics Data System (ADS)

    Lendholt, M.; Hammitzsch, M.; Esbri Palomares, M. A.

    2012-04-01

    The integration of national Tsunami Early Earning Systems (TEWS) to ocean-wide networks is a main objective of the UNESCO Intergovernmental Oceanic Commission (IOC) tsunami programme. The intention is to interlink national TEWSs leveraging warning communication during hazards. For this purpose a communication model has been developed enabling an efficient message exchange within a centre-to-centre (C2C) communication in a system-of-systems environment. The model, designed to be robust and simple, is based on existing interoperability standards from the Open Geospatial Consortium (OGC) and the Organization of the Advancement of Structured Information Standards (OASIS). For the exchange of tsunami warning bulletins the Common Alerting Protocol (CAP) is used. It supports geospatial referencing by addressing geocoded Points of Interests (POIs), Areas of Interest (AOIs) and Coastal Forecast Zones (CFZs). Moreover it supports hazard classification by standardized criticality parameters and the transmission of attachments, e.g. situation maps. The communication model also supports the exchange of sensor observations and measurements such as sea level data or earthquake parameters. For this purpose markup languages of the Sensor Web Enablement (SWE) suite are used. Both communication products, warning bulletins and sensor observations, are embedded in an envelope providing addressing and routing information using the Emergency Data Exchange Language Distribution Element (EDXL-DE). The communication model has been implemented in a first pilot based on Message Oriented Middleware (MOM). Implementation, test and validation was started in the European research project Distant Early Warning System (DEWS) and is continued successively in the project Collaborative, Complex, and Critical Decision Processes in Evolving Crises (TRIDEC). Stimulated by the concepts and results of the German Indonesian Tsunami Early Warning System (GITEWS) and based on its sensor integration platform forming the upstream information flow, the DEWS project focused on the improvement of downstream capacities of warning centres especially by improving information logistics for effective and targeted warning message aggregation for a multilingual environment. Based on these results, TRIDEC continues this task focusing on real-time intelligent information management in Earth management. The addressed challenges include the design and implementation of a robust and scalable service infrastructure supporting the integration and utilisation of existing resources with accelerated generation of large volumes of data.

  3. The effect of biochar amendment on the soil microbial community - PLFA analyses and 13C labeling results

    NASA Astrophysics Data System (ADS)

    Watzinger, A.; Feichtmair, S.; Rempt, F.; Anders, E.; Wimmer, B.; Kitzler, B.; Zechmeister-Boltenstern, S.; Horacek, M.; Zehetner, F.; Kloss, S.; Richoz, S.; Soja, G.

    2012-04-01

    The effects of biochar amendment on plant growth and on the chemical / physical soil characteristics are well explored but only few studies have investigated the impact on soil microorganisms. The response of the soil microbial community to biochar amendment was investigated by phospholipid fatty acid (PLFA) analysis in (i) a large scale pot experiment, (ii) a small scale pot experiment using 13C labeled biochar and (iii) an incubation study using 13C labeled biochar. In the large scale pot experiment, three different agricultural soils from Austria (Planosol, Cambisol, Chernozem) and four different types of biochar were investigated. In total, 25 treatments with 5 replicates each were set up and monitored over a year. The results from the pot experiments showed no significant influence of biochar amendment on the total microbial biomass in the first 100 days after biochar addition. However, discriminant analysis showed a distinction of biochar and control soils as well as a strong effect of the pyrolysis temperature on the microbial composition. The effect of biochar was dependent on the type of soil. In the Planosol, some PLFAs were affected positively, especially when adding biochar with a low pyrolysis temperature, in the first month. In the long term, microbial community composition altered. Growth of fungi and gram negative bacteria was enhanced. In the Chernozem, PLFAs from various microbial groups decreased in the long term. Variability in the incubation study was low. Consequently, many PLFAs were significantly affected by biochar amendment. Again, in the Planosol, gram negative bacteria, actinomycetes and, after 2 weeks, gram positive bacteria increased under biochar amendment whereas in the chernozem total microbial biomass and gram positive bacteria were negatively affected in the long term. The 13C labeling studies confirmed the low degradability of the biochar, i.e. no alteration of the content and the ?13C in the soil organic matter within 100 days, decreased CO2 emission after biochar addition and little 13C signature from the biochar in the respired CO2. The uptake of the labeled biochar into the microbial PLFAs was analysed and will provide an evidence if biochar was used as a carbon source. In addition, the long term effect of biochar amendment (beyond 100 days) on the soil microbial community is currently investigated. These results will be also presented in the oncoming meeting.

  4. Effectiveness of offering healthy labelled meals in improving the nutritional quality of lunch meals eaten in a worksite canteen.

    PubMed

    Lassen, A D; Beck, A; Leedo, E; Andersen, E W; Christensen, T; Mejborn, H; Thorsen, A V; Tetens, I

    2014-04-01

    Healthier meal selections at restaurants and canteens are often limited and not actively promoted. In this Danish study the effectiveness of a healthy labelling certification program in improving dietary intake and influencing edible plate waste was evaluated in a quasi-experimental study design. Employees from an intervention worksite canteen and a matched control canteen were included in the study at baseline (February 2012), after completing the certification process (end-point) and six month from end-point (follow-up) (total n=270). In order to estimate nutrient composition of the consumed lunch meals and plate waste a validated digital photographic method was used combining estimation of food intake with food nutrient composition data. Food satisfaction was rated by participants using a questionnaire. Several significant positive nutritional effects were observed at the intervention canteen including a mean decrease in energy density in the consumed meals from 561kJ/100g at baseline to 368 and 407kJ/100g at end-point and follow-up, respectively (P<0.001). No significant changes were seen with regard to food satisfaction and plate waste. In the control canteen no positive nutritional effects were observed. The results of the study highlight the potential of using healthy labelling certification programs as a possible driver for increasing both the availability and awareness of healthy meal choices, thereby improving dietary intake when eating out. PMID:24373732

  5. Blackland's flood warning system protects soldiers 

    E-print Network

    Wythe, Kathy

    2008-01-01

    stream_source_info Blackland's flood warning system protects soldiers.pdf.txt stream_content_type text/plain stream_size 2758 Content-Encoding ISO-8859-1 stream_name Blackland's flood warning system protects soldiers....pdf.txt Content-Type text/plain; charset=ISO-8859-1 tx H2O | pg. 28 Story by Kathy Wythe | pg. 28 A flood warning system resulting from a Texas AgriLife Research water quality monitoring project at Fort Hood is potentially saving lives...

  6. 21 CFR 347.52 - Labeling of astringent drug products.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... (CONTINUED) DRUGS FOR HUMAN USE SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Labeling § 347... monohydrate identified in § 347.20(b). “For temporary relief of minor skin irritations due to: .” (2) For... witch hazel identified in § 347.12(c). “Relieves minor skin irritations due to: .” (c) Warnings....

  7. 21 CFR 347.52 - Labeling of astringent drug products.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) DRUGS FOR HUMAN USE SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Labeling § 347... monohydrate identified in § 347.20(b). “For temporary relief of minor skin irritations due to: .” (2) For... witch hazel identified in § 347.12(c). “Relieves minor skin irritations due to: .” (c) Warnings....

  8. 21 CFR 347.52 - Labeling of astringent drug products.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) DRUGS FOR HUMAN USE SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Labeling § 347... monohydrate identified in § 347.20(b). “For temporary relief of minor skin irritations due to: .” (2) For... witch hazel identified in § 347.12(c). “Relieves minor skin irritations due to: .” (c) Warnings....

  9. 21 CFR 347.52 - Labeling of astringent drug products.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... (CONTINUED) DRUGS FOR HUMAN USE SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Labeling § 347... monohydrate identified in § 347.20(b). “For temporary relief of minor skin irritations due to: .” (2) For... witch hazel identified in § 347.12(c). “Relieves minor skin irritations due to: .” (c) Warnings....

  10. 21 CFR 347.52 - Labeling of astringent drug products.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) DRUGS FOR HUMAN USE SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Labeling § 347... monohydrate identified in § 347.20(b). “For temporary relief of minor skin irritations due to: .” (2) For... witch hazel identified in § 347.12(c). “Relieves minor skin irritations due to: .” (c) Warnings....

  11. 21 CFR 335.50 - Labeling of antidiarrheal drug products.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... containing any ingredient identified in § 335.10. (i) “Do not use if you have bloody or black stool”. (ii... § 335.10(b). The labeling states “helps firm stool within 24 to 48 hours”. (3) Additional indications—(i... subsalicylate in § 335.10(a): “ reduces number of bowel movements” “ helps firm stool”. (c) Warnings....

  12. 21 CFR 335.50 - Labeling of antidiarrheal drug products.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... containing any ingredient identified in § 335.10. (i) “Do not use if you have bloody or black stool”. (ii... § 335.10(b). The labeling states “helps firm stool within 24 to 48 hours”. (3) Additional indications—(i... subsalicylate in § 335.10(a): “ reduces number of bowel movements” “ helps firm stool”. (c) Warnings....

  13. 21 CFR 335.50 - Labeling of antidiarrheal drug products.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... containing any ingredient identified in § 335.10. (i) “Do not use if you have bloody or black stool”. (ii... § 335.10(b). The labeling states “helps firm stool within 24 to 48 hours”. (3) Additional indications—(i... subsalicylate in § 335.10(a): “ reduces number of bowel movements” “ helps firm stool”. (c) Warnings....

  14. 21 CFR 335.50 - Labeling of antidiarrheal drug products.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... containing any ingredient identified in § 335.10. (i) “Do not use if you have bloody or black stool”. (ii... § 335.10(b). The labeling states “helps firm stool within 24 to 48 hours”. (3) Additional indications—(i... subsalicylate in § 335.10(a): “ reduces number of bowel movements” “ helps firm stool”. (c) Warnings....

  15. The effect of the state of differentiation on labeling of epidermal cell surface glycoproteins

    SciTech Connect

    Brysk, M.M.; Snider, J.M.

    1982-05-01

    Epidermal cells were grown in a medium in which the Ca++ concentration controlled the stage of differentiation. Cell surface molecules of differentiated and undifferentiated cells were compared by lactoperoxidase-catalyzed iodination, by the interaction with /sup 125/I-lectins, and by the metabolic incorporation of L-(/sup 3/H)-fucose. Molecular weights of the labeled components were determined by SDS-PAGE and autoradiography. After lactoperoxidase iodination, most of the radioactivity was found in polypeptide bands of 79,000, 65,000 and 56,000 daltons. The 79,000 band is the most intense for undifferentiated cells but disappears as differentiation proceeds. The 56,000 band is present in normal cells at all stages of differentiation but is absent from neoplastic cells. Glycoproteins reacted with /sup 125/I-lectins were found at 180,000, 130,000 and 85,000 daltons. The 130,000 band was the most prominent for differentiated cells labeled with wheat germ agglutinin but was essentially absent from the undifferentiated cells. With Ricinus communis agglutinin, this band was weaker for undifferentiated than for differentiated cells but was the most intense for both. After metabolic incorporation of tritiated fucose, radioactive glycoproteins were found at 130,000 and 85,000 daltons, with comparable intensities for differentiated and undifferentiated cells.

  16. Natural abundance deuterium and 18-oxygen effects on the precision of the doubly labeled water method

    NASA Technical Reports Server (NTRS)

    Horvitz, M. A.; Schoeller, D. A.

    2001-01-01

    The doubly labeled water method for measuring total energy expenditure is subject to error from natural variations in the background 2H and 18O in body water. There is disagreement as to whether the variations in background abundances of the two stable isotopes covary and what relative doses of 2H and 18O minimize the impact of variation on the precision of the method. We have performed two studies to investigate the amount and covariance of the background variations. These were a study of urine collected weekly from eight subjects who remained in the Madison, WI locale for 6 wk and frequent urine samples from 14 subjects during round-trip travel to a locale > or = 500 miles from Madison, WI. Background variation in excess of analytical error was detected in six of the eight nontravelers, and covariance was demonstrated in four subjects. Background variation was detected in all 14 travelers, and covariance was demonstrated in 11 subjects. The median slopes of the regression lines of delta2H vs. delta18O were 6 and 7, respectively. Modeling indicated that 2H and 18O doses yielding a 6:1 ratio of final enrichments should minimize this error introduced to the doubly labeled water method.

  17. Beware Unregulated Stem Cell Treatments, Experts Warn

    MedlinePLUS

    ... gov/medlineplus/news/fullstory_154536.html Beware Unregulated Stem Cell Treatments, Experts Warn Clinics selling treatments that ... clinics across the United States are offering unapproved stem cell treatments for conditions from baldness to heart ...

  18. 49 CFR 229.113 - Warning notice.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...STANDARDS Safety Requirements Steam Generators § 229.113 Warning notice. Whenever any steam generator has been shut down because of defects...conspicuously attached near the steam generator starting controls until the...

  19. 49 CFR 229.113 - Warning notice.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...STANDARDS Safety Requirements Steam Generators § 229.113 Warning notice. Whenever any steam generator has been shut down because of defects...conspicuously attached near the steam generator starting controls until the...

  20. 49 CFR 229.113 - Warning notice.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...STANDARDS Safety Requirements Steam Generators § 229.113 Warning notice. Whenever any steam generator has been shut down because of defects...conspicuously attached near the steam generator starting controls until the...

  1. 49 CFR 229.113 - Warning notice.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...STANDARDS Safety Requirements Steam Generators § 229.113 Warning notice. Whenever any steam generator has been shut down because of defects...conspicuously attached near the steam generator starting controls until the...

  2. 49 CFR 229.113 - Warning notice.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...STANDARDS Safety Requirements Steam Generators § 229.113 Warning notice. Whenever any steam generator has been shut down because of defects...conspicuously attached near the steam generator starting controls until the...

  3. 49 CFR 234.259 - Warning time.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GRADE CROSSING SIGNAL SYSTEM SAFETY AND STATE ACTION PLANS...system is modified because of a change in train speeds. Electronic devices that accurately determine actual warning time may...

  4. National Weather Service: Watch, Warning, Advisory Display

    MedlinePLUS

    ... Fire Wx Outlooks RSS Feeds E-Mail Alerts Weather Information Storm Reports Storm Reports Dev. NWS Hazards ... Watch/Warning Map National RADAR Product Archive NOAA Weather Radio Research Non-op. Products Forecast Tools Svr. ...

  5. 33 CFR 127.1113 - Warning signs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... section, bear the following text: Warning Dangerous Cargo No visitors No Smoking No Open Lights (b) Each... centimeters (3 inches) high. (c) The words “No Smoking” and “No Open Lights” may be omitted when the...

  6. 33 CFR 127.1113 - Warning signs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... section, bear the following text: Warning Dangerous Cargo No visitors No Smoking No Open Lights (b) Each... centimeters (3 inches) high. (c) The words “No Smoking” and “No Open Lights” may be omitted when the...

  7. Meteorological Monitoring And Warning Computer Network

    NASA Technical Reports Server (NTRS)

    Evans, Randolph J.; Dianic, Allan V.; Moore, Lien N.

    1996-01-01

    Meteorological monitoring system (MMS) computer network tracks weather conditions and issues warnings when weather hazards are about to occur. Receives data from such meteorological instruments as wind sensors on towers and lightning detectors, and compares data with weather restrictions specified for outdoor activities. If weather violates restriction, network generates audible and visible alarms to alert people involved in activity. Also displays weather and toxic diffusion data and disseminates weather forecasts, advisories, and warnings to workstations.

  8. Ethical dilemmas related to predictions and warnings of impending natural disaster.

    PubMed

    Phua, Kai-Lit; Hue, J W

    2013-01-01

    Scientists and policy makers issuing predictions and warnings of impending natural disaster are faced with two major challenges, that is, failure to warn and issuing a false alarm. The consequences of failure to warn can be serious for society overall, for example, significant economic losses, heavy infrastructure and environmental damage, large number of human casualties, and social disruption. Failure to warn can also have serious for specific individuals, for example, legal proceedings against disaster research scientists, as in the L'Aquila earthquake affair. The consequences of false alarms may be less serious. Nevertheless, false alarms may violate the principle of nonmaleficence (do no harm), affect individual autonomy (eg, mandatory evacuations), and may result in the "cry wolf" effect. Other ethical issues associated with natural disasters include the promotion of global justice through international predisaster technical assistance and postdisaster aid. Social justice within a particular country is promoted through greater postdisaster aid allocation to the less privileged. PMID:24481888

  9. Labelling and 'Dear Doctor' letters: are they noncommittal?

    PubMed

    van Grootheest, A C Kees; Edwards, I Ralph

    2002-01-01

    Over the past few years, a number of drugs have been withdrawn for safety reasons, either by drug approval authorities, or by the manufacturer. A recent example is the withdrawal of cerivastatin in connection with rhabdomyolysis. Several other drugs have also been taken off the market as a security measure, not because the nature of the risk involved was unknown but because the risk had proved apparently uncontainable. It seems that the inclusion of a warning or contraindication in the Summary of Product Characteristics (SPC) or sending a 'Dear Doctor' letter is insufficient to ensure compliant prescription behaviour. There appears to be a discrepancy between the careful use of evidence underpinning the SPC content and formal warnings and changes to the SPC and the effect they have on the prescription and dispensing of the drugs involved. This results in undue loss or damage for both the manufacturer and the patient. There are no easy solutions to tackle this problem; the ineffectiveness of labelling and 'Dear Doctor' letters has ramifications for the whole regulatory/ industrial/educational complex. We discuss briefly four possible strategies for improving the current situation, with the emphasis on the place the prescriber has in this process. The first strategy is education-based. Clinicians need to know about the comparative merits of the effectiveness and risk of drugs, as well as how they work pharmacologically, toxicologically, and what interactions they have with each other. The second strategy involves improving the information available for clinicians. Frequently, physicians do not consult the SPC for verification, leaving aside whether they have taken notice of the contents of the official SPC in the first place. It is recommended that the accessibility of SPCs is enhanced for doctors and pharmacists, drawing attention specifically to any changes. There needs to be a single body of information that covers every drug. The third strategy involves communication. There is much to be done in this area both in terms of follow-up and understanding of health professional's behaviour and how to empower best practise. The final strategy involves professional freedom. It goes without saying that doctors who issue off-label prescriptions may need to justify their actions. Deviating from the SPC should always be a considered decision and health professionals need to be aware of the additional responsibilities associated with such a decision. The dispensing pharmacist can play an important role in the implementation of warnings and contraindications. PMID:12452731

  10. Carbon Nanostructure-Based Field-Effect Transistors for Label-Free Chemical/Biological Sensors

    PubMed Central

    Hu, PingAn; Zhang, Jia; Li, Le; Wang, Zhenlong; O’Neill, William; Estrela, Pedro

    2010-01-01

    Over the past decade, electrical detection of chemical and biological species using novel nanostructure-based devices has attracted significant attention for chemical, genomics, biomedical diagnostics, and drug discovery applications. The use of nanostructured devices in chemical/biological sensors in place of conventional sensing technologies has advantages of high sensitivity, low decreased energy consumption and potentially highly miniaturized integration. Owing to their particular structure, excellent electrical properties and high chemical stability, carbon nanotube and graphene based electrical devices have been widely developed for high performance label-free chemical/biological sensors. Here, we review the latest developments of carbon nanostructure-based transistor sensors in ultrasensitive detection of chemical/biological entities, such as poisonous gases, nucleic acids, proteins and cells. PMID:22399927

  11. Watson-Crick Petri net languages: The effect of labeling strategies

    NASA Astrophysics Data System (ADS)

    Jan, Nurhidaya Mohamad; Heng, Fong Wan; Sarmin, Nor Haniza; Turaev, Sherzod

    2014-07-01

    A Watson-Crick automaton is an automaton that works on tapes which are double stranded sequences of symbols related by Watson-Crick complementarity that are similar to the DNA molecules. However, this automaton cannot exploit the other fundamental features of DNA molecules such as the massive parallelism. Watson-Crick automata can be related to a model known as the Petri net. Petri net is a model based on the concepts of asynchronous and concurrent operation by the parts of a system and the realization by the parts can be represented by a graph or a net. From the relation between Watson-Crick automata and Petri net, a new model namely Watson-Crick Petri net has been developed. The language generated by Watson-Crick Petri net is a set of labeled sequences corresponding to the occurrence sequences of the model. In this research, some properties of languages generated by Watson-Crick Petri net are investigated.

  12. The spatial effect of protein deuteration on nitroxide spin-label relaxation: Implications for EPR distance measurement

    NASA Astrophysics Data System (ADS)

    El Mkami, Hassane; Ward, Richard; Bowman, Andrew; Owen-Hughes, Tom; Norman, David G.

    2014-11-01

    Pulsed electron-electron double resonance (PELDOR) coupled with site-directed spin labeling is a powerful technique for the elucidation of protein or nucleic acid, macromolecular structure and interactions. The intrinsic high sensitivity of electron paramagnetic resonance enables measurement on small quantities of bio-macromolecules, however short relaxation times impose a limit on the sensitivity and size of distances that can be measured using this technique. The persistence of the electron spin-echo, in the PELDOR experiment, is one of the most crucial limitations to distance measurement. At a temperature of around 50 K one of the predominant factors affecting persistence of an echo, and as such, the sensitivity and measurable distance between spin labels, is the electron spin echo dephasing time (Tm). It has become normal practice to use deuterated solvents to extend Tm and recently it has been demonstrated that deuteration of the underlying protein significantly extends Tm. Here we examine the spatial effect of segmental deuteration of the underlying protein, and also explore the concentration and temperature dependence of highly deuterated systems.

  13. The spatial effect of protein deuteration on nitroxide spin-label relaxation: Implications for EPR distance measurement

    PubMed Central

    El Mkami, Hassane; Ward, Richard; Bowman, Andrew; Owen-Hughes, Tom; Norman, David G.

    2014-01-01

    Pulsed electron–electron double resonance (PELDOR) coupled with site-directed spin labeling is a powerful technique for the elucidation of protein or nucleic acid, macromolecular structure and interactions. The intrinsic high sensitivity of electron paramagnetic resonance enables measurement on small quantities of bio-macromolecules, however short relaxation times impose a limit on the sensitivity and size of distances that can be measured using this technique. The persistence of the electron spin-echo, in the PELDOR experiment, is one of the most crucial limitations to distance measurement. At a temperature of around 50 K one of the predominant factors affecting persistence of an echo, and as such, the sensitivity and measurable distance between spin labels, is the electron spin echo dephasing time (Tm). It has become normal practice to use deuterated solvents to extend Tm and recently it has been demonstrated that deuteration of the underlying protein significantly extends Tm. Here we examine the spatial effect of segmental deuteration of the underlying protein, and also explore the concentration and temperature dependence of highly deuterated systems. PMID:25310878

  14. Inversion of tsunami waveforms and tsunami warning

    NASA Astrophysics Data System (ADS)

    An, Chao

    Ever since the 2004 Indian Ocean tsunami, the technique of inversion of tsunami data and the importance of tsunami warning have drawn the attention of many researchers. However, since tsunamis are rare and extreme events, developed inverse techniques lack validation, and open questions rise when they are applied to a real event. In this study, several of those open questions are investigated, i.e., the wave dispersion, bathymetry grid size and subfault division. First, tsunami records from three large tsunami events -- 2010 Maule, 2011 Tohoku and 2012 Haida Gwaii -- are analyzed to extract the main characteristics of the leading tsunami waves. Using the tool of wavelet transforming, the instant wave period can be obtained and thus the dispersive parameter mu2 can be calculated. mu2 is found to be smaller than 0.02 for all records, indicating that the wave dispersion is minor for the propagation of tsunami leading waves. Second, inversions of tsunami data are carried out for three tsunami events -- 2011 Tohoku, 2012 Haida Gwaii and 2014 Iquique. By varying the subfault size and the bathymetry grid size in the inversions, general rules are established for choosing those two parameters. It is found that the choice of bathymetry grid size depends on various parameters, such as the subfault size and the depth of subfaults. The global bathymetry data GEBCO with spatial resolution of 30 arcsec is generally good if the subfault size is larger than 40 km x 40 km; otherwise, bathymetry data with finer resolution is desirable. Detailed instructions of choosing the bathymetry size can be found in Chapter 2. By contrast, the choice of subfault size has much more freedom; our study shows that the subfault size can be very large without significant influence on the predicted tsunami waves. For earthquakes with magnitude of 8.0 ˜ 9.0, the subfault size can be 60 km ˜ 100 km. In our study, the maximum subfault size results in 9 ˜ 16 subfault patches on the ruptured fault surface, so we infer that the maximum size of the subfault can be 1/4 to 1/3 of the scale of the faulting area. In Chapter 2, we also developed a method using the inverse residual to evaluate the effectiveness of tsunami buoys of different number and locations in the inversion. Results show that 2 ˜ 4 tsunami buoys are sufficient to constrain the source parameters quite well if they are optimally located. Adding data from more tsunami buoys into the inversion does not significantly improve the results. In addition, near-field stations in the source region do not have advantage against far-field stations in constraining the earthquake source parameters. Conversely, if the near-field data have short but large-amplitude waves and only such data are used in the inversion, it can result in very large but unreal slip near the seabed. The optimal locations for tsunami buoys of different number can also be obtained from this method. Inversions of tele-seismic data show that the inverse results do not necessarily predict the tsunami waves, unless iterative forward modeling techniques are applied to adjust the inverse parameters. Thus, from the standpoint of tsunami warning, tele-seismic data are not able to precisely predict the tsunami wave height or an accurate inundation map, although the estimation of earthquake magnitude and depth might be enough to issue a crude warning. In addition, numerical experiments are conducted and measurements of the computational time show that the calculation of tsunami Green's functions for an area of ˜ 30° only takes several minutes using 256 computational cores. Thus, it is possible to calculate the Green's functions in real time for a tsunami warning system. Finally, a case study is conducted for the South China Sea using the method of inverse residual, leading to recommendations of number and location of tsunami buoys required for a warning system near the Manila trench.

  15. Development of a Patient-Centered Bilingual Prescription Drug Label

    PubMed Central

    Mohan, Arun; Riley, M. Brian; Boyington, Dane; Johnston, Phillip; Trochez, Karen; Jennings, Callie; Mashburn, Jennie; Kripalani, Sunil

    2013-01-01

    Research shows that prescription drug labels are often difficult for patients to understand, which contributes to medication errors and nonadherence. In this study, the authors developed and qualitatively evaluated an evidence-based bilingual prescription container label designed to improve understanding. The authors developed several prototypes in English only or in English and Spanish. The labels included an image of the drug, an icon to show its purpose, and plain-language instructions presented in a 4-time-of-day table. In 5 focus groups and interviews that included 57 participants, patients and pharmacists critically reviewed the designs and compared them with traditional medication labels and reformatted labels without illustrations. Patients strongly preferred labels that grouped patient-relevant content, highlighted key information, and included drug indication icons. They also preferred having the 4-time-of-day table and plain-language text instructions as opposed to either one alone. Patients preferred having pertinent warnings on the main label instead of auxiliary labels. Pharmacists and Latino patients valued having Spanish and English instructions on the label, so both parties could understand the content. The final label design adheres to the latest national- and state-level recommendations for label format and incorporates additional improvements on the basis of patient and pharmacist input. This design may serve as a prototype for improving prescription drug labeling. PMID:24093345

  16. Tsunami Generation Modelling for Early Warning Systems

    NASA Astrophysics Data System (ADS)

    Annunziato, A.; Matias, L.; Ulutas, E.; Baptista, M. A.; Carrilho, F.

    2009-04-01

    In the frame of a collaboration between the European Commission Joint Research Centre and the Institute of Meteorology in Portugal, a complete analytical tool to support Early Warning Systems is being developed. The tool will be part of the Portuguese National Early Warning System and will be used also in the frame of the UNESCO North Atlantic Section of the Tsunami Early Warning System. The system called Tsunami Analysis Tool (TAT) includes a worldwide scenario database that has been pre-calculated using the SWAN-JRC code (Annunziato, 2007). This code uses a simplified fault generation mechanism and the hydraulic model is based on the SWAN code (Mader, 1988). In addition to the pre-defined scenario, a system of computers is always ready to start a new calculation whenever a new earthquake is detected by the seismic networks (such as USGS or EMSC) and is judged capable to generate a Tsunami. The calculation is performed using minimal parameters (epicentre and the magnitude of the earthquake): the programme calculates the rupture length and rupture width by using empirical relationship proposed by Ward (2002). The database calculations, as well the newly generated calculations with the current conditions are therefore available to TAT where the real online analysis is performed. The system allows to analyze also sea level measurements available worldwide in order to compare them and decide if a tsunami is really occurring or not. Although TAT, connected with the scenario database and the online calculation system, is at the moment the only software that can support the tsunami analysis on a global scale, we are convinced that the fault generation mechanism is too simplified to give a correct tsunami prediction. Furthermore short tsunami arrival times especially require a possible earthquake source parameters data on tectonic features of the faults like strike, dip, rake and slip in order to minimize real time uncertainty of rupture parameters. Indeed the earthquake parameters available right after an earthquake are preliminary and could be inaccurate. Determining which earthquake source parameters would affect the initial height and time series of tsunamis will show the sensitivity of the tsunami time series to seismic source details. Therefore a new fault generation model will be adopted, according to the seismotectonics properties of the different regions, and finally included in the calculation scheme. In order to do this, within the collaboration framework of Portuguese authorities, a new model is being defined, starting from the seismic sources in the North Atlantic, Caribbean and Gulf of Cadiz. As earthquakes occurring in North Atlantic and Caribbean sources may affect Portugal mainland, the Azores and Madeira archipelagos also these sources will be included in the analysis. Firstly we have started to examine the geometries of those sources that spawn tsunamis to understand the effect of fault geometry and depths of earthquakes. References: Annunziato, A., 2007. The Tsunami Assesment Modelling System by the Joint Research Center, Science of Tsunami Hazards, Vol. 26, pp. 70-92. Mader, C.L., 1988. Numerical modelling of water waves, University of California Press, Berkeley, California. Ward, S.N., 2002. Tsunamis, Encyclopedia of Physical Science and Technology, Vol. 17, pp. 175-191, ed. Meyers, R.A., Academic Press.

  17. [Early warning on measles through the neural networks].

    PubMed

    Yu, Bin; Ding, Chun; Wei, Shan-bo; Chen, Bang-hua; Liu, Pu-lin; Luo, Tong-yong; Wang, Jia-gang; Pan, Zhi-wei; Lu, Jun-an

    2011-01-01

    To discuss the effects on early warning of measles, using the neural networks. Based on the available data through monthly and weekly reports on measles from January 1986 to August 2006 in Wuhan city. The modal was developed using the neural networks to predict and analyze the prevalence and incidence of measles. When the dynamic time series modal was established with back propagation (BP) networks consisting of two layers, if p was assigned as 9, the convergence speed was acceptable and the correlation coefficient was equal to 0.85. It was more acceptable for monthly forecasting the specific value, but better for weekly forecasting the classification under probabilistic neural networks (PNN). When data was big enough to serve the purpose, it seemed more feasible for early warning using the two-layer BP networks. However, when data was not enough, then PNN could be used for the purpose of prediction. This method seemed feasible to be used in the system for early warning. PMID:21518546

  18. Early warning signals of tipping points in periodically forced systems

    NASA Astrophysics Data System (ADS)

    Williamson, M. S.; Bathiany, S.; Lenton, T. M.

    2015-11-01

    The prospect of finding generic early warning signals of an approaching tipping point in a complex system has generated much recent interest. Existing methods are predicated on a separation of timescales between the system studied and its forcing. However, many systems, including several candidate tipping elements in the climate system, are forced periodically at a timescale comparable to their internal dynamics. Here we find alternative early warning signals of tipping points due to local bifurcations in systems subjected to periodic forcing whose time scale is similar to the period of the forcing. These systems are not in, or close to, a fixed point. Instead their steady state is described by a periodic attractor. We show that the phase lag and amplification of the system response provide early warning signals, based on a linear dynamics approximation. Furthermore, the power spectrum of the system's time series reveals the generation of harmonics of the forcing period, the size of which are proportional to how nonlinear the system's response is becoming with nonlinear effects becoming more prominent closer to a bifurcation. We apply these indicators to a simple conceptual system and satellite observations of Arctic sea ice area, the latter conjectured to have a bifurcation type tipping point. We find no detectable signal of the Arctic sea ice approaching a local bifurcation.

  19. Hydrologic Ensemble Forecasts for Flash Flood Warnings at Ungauged Locations

    NASA Astrophysics Data System (ADS)

    Demargne, Julie; Javelle, Pierre; Organde, Didier; Ramos, Maria-Helena

    2013-04-01

    Development of operational flash flood warning systems is one of the challenges in operational hydrology: flash floods are devastating but difficult to monitor and predict due to their nature. To provide flash flood warnings for ungauged basins, Météo-France and Irstea (formally Cemagref) have developed a discharge-threshold flood warning system called AIGA, which combines radar-gauge rainfall grids with a simplified distributed rainfall-runoff model run every 15 minutes at a 1-km² resolution. Operational since 2005 in the Southern part of France, the AIGA system produces, every 15 minutes, a map of the river network with a color chart indicating the range of the estimated return period of the ongoing flood event. To increase forecast lead time and quantify the forcing input uncertainty, the rainfall-runoff distributed model ingests the 11 precipitation ensemble members from the PEARP ensemble prediction system of Météo-France. Performance of the experimental probabilistic precipitation and flow forecasts is evaluated from a variety of ensemble verification metrics (e.g., Continuous Ranked Probability Skill Score, Relative Operating Characteristic score) for different French basins. We also discuss planned enhancements and challenges to assess other sources of hydrologic uncertainty and effectively communicate the uncertainty information to forecasters for better risk-based decision making.

  20. Earthquake Early Warning Beta Users: Java, Modeling, and Mobile Apps

    NASA Astrophysics Data System (ADS)

    Strauss, J. A.; Vinci, M.; Steele, W. P.; Allen, R. M.; Hellweg, M.

    2014-12-01

    Earthquake Early Warning (EEW) is a system that can provide a few to tens of seconds warning prior to ground shaking at a user's location. The goal and purpose of such a system is to reduce, or minimize, the damage, costs, and casualties resulting from an earthquake. A demonstration earthquake early warning system (ShakeAlert) is undergoing testing in the United States by the UC Berkeley Seismological Laboratory, Caltech, ETH Zurich, University of Washington, the USGS, and beta users in California and the Pacific Northwest. The beta users receive earthquake information very rapidly in real-time and are providing feedback on their experiences of performance and potential uses within their organization. Beta user interactions allow the ShakeAlert team to discern: which alert delivery options are most effective, what changes would make the UserDisplay more useful in a pre-disaster situation, and most importantly, what actions users plan to take for various scenarios. Actions could include: personal safety approaches, such as drop cover, and hold on; automated processes and procedures, such as opening elevator or fire stations doors; or situational awareness. Users are beginning to determine which policy and technological changes may need to be enacted, and funding requirements to implement their automated controls. The use of models and mobile apps are beginning to augment the basic Java desktop applet. Modeling allows beta users to test their early warning responses against various scenarios without having to wait for a real event. Mobile apps are also changing the possible response landscape, providing other avenues for people to receive information. All of these combine to improve business continuity and resiliency.

  1. Early warning of atmospheric regime transitions using transfer operators

    NASA Astrophysics Data System (ADS)

    Tantet, Alexis; Dijkstra, Henk

    2015-04-01

    The existence of persistent midlatitude atmospheric regimes, such as blocking events, with time scales larger than 5-10 days and indications of preferred transition paths between them motivates the development of early-warning indicators of regime transitions. Here, we use a barotropic model of the northern midlatitudes winter flow to study such meta-stable regimes. We look at estimates of transfer operators acting on densities evolving on a reduced phase space spanned by the first Empirical Orthogonal Functions of the streamfunction and develop an early-warning indicator of zonal to blocked flow transition. The study of the spectra of transfer operators estimated for different lags reveals a multi-level structure in the flow as well as the effect of memory on the reduced dynamics due to past interactions between the resolved and unresolved variables. The slowest motions in the reduced phase space are thereby found to have time scales larger than 8 days and to behave as Markovian for larger lags. These motions are associated with meta-stable regimes and their transitions and can be detected as almost-invariant sets of the transfer operator. The early-warning indicator is based on the action on an initial density of products of the transfer operators estimated for sufficiently long lags, making use of the semi-group property of these operators and shows relatively good Peirce skill score. From the energy budget of the model, we are able to explain the meta-stability of the regimes and the existence of preferred transition paths as the manifestation of barotropic instability. Finally, even though the model is highly simplified, the skill of the early warning indicator is promising, suggesting that the transfer operator approach can be used in parallel to an operational deterministic model for stochastic prediction or to assess forecast uncertainty.

  2. Systematic ranging and late warning asteroid impacts

    NASA Astrophysics Data System (ADS)

    Farnocchia, D.; Chesley, S. R.; Micheli, M.

    2015-09-01

    We describe systematic ranging, an orbit determination technique suitable to assess the near-term Earth impact hazard posed by newly discovered asteroids. For these late warning cases, the time interval covered by the observations is generally short, perhaps a few hours or even less, which leads to severe degeneracies in the orbit estimation process. The systematic ranging approach gets around these degeneracies by performing a raster scan in the poorly-constrained space of topocentric range and range rate, while the plane of sky position and motion are directly tied to the recorded observations. This scan allows us to identify regions corresponding to collision solutions, as well as potential impact times and locations. From the probability distribution of the observation errors, we obtain a probability distribution in the orbital space and then estimate the probability of an Earth impact. We show how this technique is effective for a number of examples, including 2008 TC3 and 2014 AA, the only two asteroids to date discovered prior to impact.

  3. Assessment of flash flood warning procedures

    NASA Astrophysics Data System (ADS)

    Johnson, Lynn E.

    2000-01-01

    Assessment of four alternate flash flood warning procedures was conducted to ascertain their suitability for forecast operations using radar-rainfall imagery. The procedures include (1) areal mean basin effective rainfall, (2) unit hydrograph, (3) time-area, and (4) 2-D numerical modeling. The Buffalo Creek flash flood of July 12, 1996, was used as a case study for application of each of the procedures. A significant feature of the Buffalo Creek event was a forest fire that occurred a few months before the flood and significantly affected watershed runoff characteristics. Objectives were to assess the applicability of the procedures for watersheds having spatial and temporal scale similarities to Buffalo Creek, to compare their technical characteristics, and to consider forecaster usability. Geographic information system techniques for hydrologic database development and flash flood potential computations are illustrated. Generalizations of the case study results are offered relative to their suitability for flash flood forecasting operations. Although all four methods have relative advantages, their application to the Buffalo Creek event resulted in mixed performance. Failure of any method was due primarily to uncertainties of the land surface response (i.e., burn area imperviousness). Results underscore the need for model calibration; a difficult requirement for real-time forecasting.

  4. TRMM Applications for Rainfall-Induced Landslide Early Warning

    NASA Astrophysics Data System (ADS)

    Dok, A.; Fukuoka, H.; Hong, Y.

    2012-04-01

    Early warning system (EWS) is the most effective method in saving lives and reducing property damages resulted from the catastrophic landslides if properly implemented in populated areas of landslide-prone nations. For predicting the occurrence of landslides, it requires examination of empirical relationship between rainfall characteristics and past landslide occurrence. In developed countries like Japan and the US, precipitation is monitored by rain radars and ground-based rain gauge matrix. However, in developing regions like Southeast Asian countries, very limited number of rain gauges is available, and there is no implemented methodology for issuing effective warming of landslides yet. Correspondingly, satellite precipitation monitoring could be therefore a possible and promising solution for launching landslide quasi-real-time early warning system in those countries. It is due to the fact that TMPA (TRMM Multi-satellite Precipitation Analysis) can provides a globally calibration-based sequential scheme for combining precipitation estimates from multiple satellites, and gauge analyses where feasible, at fine scales (3-hourly with 0.25°x0.25° spatial resolution). It is available both after and in quasi-real time, calibrated by TRMM Combined Instrument and TRMM Microwave Imager precipitation product. However, validation of ground based rain gauge and TRMM satellite data in the vulnerable regions is still not yet operative. Snake-line/Critical-line and Soil Water Index (SWI) are used for issuing warning of landslide occurrence in Japan; whereas, Caine criterion is preferable in Europe and western nations. Herewith, it presents rainfall behavior which took place in Beichuan city (located on the 2008 Chinese Wenchuan earthquake fault), Hofu and Shobara cities in Japan where localized heavy rainfall attacked in 2009 and 2010, respectively, from TRMM 3B42RT correlated with ground based rain gauge data. The 1-day rainfall intensity and 15-day cumulative rainfall (snake line) were independently plotted to investigate the impact of short-term rainfall intensity and accumulated effective rainfall volume respectively for obtaining some probabilistic threshold. Japanese SWI was also tested to distribute threshold regarding to highly nonlinear rainfall patterns in predicting the landslide occurrence through the plot of total water of 3 serial tank models and daily precipitation. As a result, the snake line plots using TMPA work well for landslide warning in the selected cities; while SWI plots shows unusual peak value on the day of the debris flow occurrence. Graph of daily precipitation vs SWI implies possible zone of critical line, and second peak appearance 1 day before, indicating possibility of early warning.

  5. Effects of Add-on Ramelteon on Cognitive Impairment in Patients with Schizophrenia: An Open-label Pilot Trial

    PubMed Central

    Takahashi, Michio; Suzuki, Masatoshi; Tsuruoka, Yoshiaki; Sato, Koichi

    2014-01-01

    Objective This open-label study examined the effects of ramelteon on cognitive functions in 10 outpatients with schizophrenia. Methods Ramelteon (8 mg/day) was administered to 10 patients with schizophrenia for six months. The verbal fluency test, Trail-Making Test, the Wisconsin Card Sorting Test, the Stroop Test, the Digit Span Distraction Test, Iowa Gambling Task, the Rey Auditory Verbal Learning Test were evaluated at baseline and 6 months after treatment with ramelteon. Results Ramelteon improved significantly the scores of Rey Auditory Verbal Learning Test. Additionally, ramelteon exerted improvements in the verbal fluency and Iowa Gambling Task in 4 patients. Conclusion Ramelteon could be a potential therapeutic drug, in adjunctive treatment of learning and memory deficits seen in patients with schizophrenia. PMID:25598825

  6. A hazard-independent approach for the standardised multi-channel dissemination of warning messages

    NASA Astrophysics Data System (ADS)

    Esbri Palomares, M. A.; Hammitzsch, M.; Lendholt, M.

    2012-04-01

    The tsunami disaster affecting the Indian Ocean region on Christmas 2004 demonstrated very clearly the shortcomings in tsunami detection, public warning processes as well as intergovernmental warning message exchange in the Indian Ocean region. In that regard, early warning systems require that the dissemination of early warning messages has to be executed in way that ensures that the message delivery is timely; the message content is understandable, usable and accurate. To that end, diverse and multiple dissemination channels must be used to increase the chance of the messages reaching all affected persons in a hazard scenario. In addition to this, usage of internationally accepted standards for the warning dissemination such as the Common Alerting Protocol (CAP) and Emergency Data Exchange Language (EDXL) Distribution Element specified by the Organization for the Advancement of Structured Information Standards (OASIS) increase the interoperability among different warning systems enabling thus the concept of system-of-systems proposed by GEOSS. The project Distant Early Warning System (DEWS), co-funded by the European Commission under the 6th Framework Programme, aims at strengthening the early warning capacities by building an innovative generation of interoperable tsunami early warning systems based on the above mentioned concepts following a Service-oriented Architecture (SOA) approach. The project focuses on the downstream part of the hazard information processing where customized, user-tailored warning messages and alerts flow from the warning centre to the responsible authorities and/or the public with their different needs and responsibilities. The information logistics services within DEWS generate tailored EDXL-DE/CAP warning messages for each user that must receive the message according to their preferences, e.g., settings for language, interested areas, dissemination channels, etc.. However, the significant difference in the implementation and capabilities of different dissemination channels such as SMS, email and television, have bearing on the information processing required for delivery and consumption of a DEWS EDXL-DE/CAP message over each dissemination channel. These messages may include additional information in the form of maps, graphs, documents, sensor observations, etc. Therefore, the generated messages are pre-processed by channel adaptors in the information dissemination services converting it into a format that is suitable for end-to-end delivery over the dissemination channels without any semantic distortion. The approach followed by DEWS for disseminating warnings not only relies on traditional communication ways used by the already established early warnings such as the delivery of faxes and phone calls but takes into consideration the use of other broadly used communication channels such as SMS, email, narrowcast and broadcast television, instant messaging, Voice over IP, and radio. It also takes advantage of social media channels like RSS feeds, Facebook, Twitter, etc., enabling a multiplier effect, like in the case of radio and television, and thus allowing to create mash-ups by aggregating other sources of information to the original message. Finally, status information is also important in order to assess and understand whether the process of disseminating the warning to the message consumers has been successfully completed or the process failed at some point of the dissemination chain. To that end, CAP-based messages generated within the information dissemination services provide the semantics for those fields that are of interest within the context of reporting the warning dissemination status in DEWS.

  7. Effects of calorie labeling and value size pricing on fast food meal choices: Results from an experimental trial

    PubMed Central

    Harnack, Lisa J; French, Simone A; Oakes, J Michael; Story, Mary T; Jeffery, Robert W; Rydell, Sarah A

    2008-01-01

    Background Although point-of-purchase calorie labeling at restaurants has been proposed as a strategy for improving consumer food choices, a limited number of studies have evaluated this approach. Likewise, little research has been conducted to evaluate the influence of value size pricing on restaurant meal choices. Methods To examine the effect of point-of-purchase calorie information and value size pricing on fast food meal choices a randomized 2 × 2 factorial experiment was conducted in which participants ordered a fast food meal from one of four menus that varied with respect to whether calorie information was provided and whether value size pricing was used. Study participants included 594 adolescents and adults who regularly ate at fast food restaurants. Study staff recorded the foods ordered and consumed by each participant. Participants also completed surveys to assess attitudes, beliefs and practices related to fast food and nutrition. Results No significant differences in the energy composition of meals ordered or eaten were found between menu conditions. The average energy content of meals ordered by those randomized to a menu that included calorie information and did not include value size pricing was 842 kcals compared with 827 kcals for those who ordered their meal from a menu that did not include calorie information but had value size pricing (control menu). Results were similar in most analyses conducted stratified by factors such as age, race and education level. Conclusion Additional research is needed to better evaluate the effects of calorie labeling and value size pricing on fast food meal choices. Studies in which participants are repeatedly exposed to these factors are needed since long term exposure may be required for behavior change. PMID:19061510

  8. Environment Agency England flood warning systems

    NASA Astrophysics Data System (ADS)

    Strong, Chris; Walters, Mark; Haynes, Elizabeth; Dobson, Peter

    2015-04-01

    Context In England around 5 million homes are at risk of flooding. We invest significantly in flood prevention and management schemes but we can never prevent all flooding. Early alerting systems are fundamental to helping us reduce the impacts of flooding. The Environment Agency has had the responsibility for flood warning since 1996. In 2006 we invested in a new dissemination system that would send direct messages to pre-identified recipients via a range of channels. Since then we have continuously improved the system and service we offer. In 2010 we introduced an 'opt-out' service where we pre-registered landline numbers in flood risk areas, significantly increasing the customer base. The service has performed exceptionally well under intense flood conditions. Over a period of 3 days in December 2013, when England was experiencing an east coast storm surge, the system sent nearly 350,000 telephone messages, 85,000 emails and 70,000 text messages, with a peak call rate of around 37,000 per hour and 100% availability. The Floodline Warnings Direct (FWD) System FWD provides warnings in advance of flooding so that people at risk and responders can take action to minimise the impact of the flood. Warnings are sent via telephone, fax, text message, pager or e-mail to over 1.1 million properties located within flood risk areas in England. Triggers for issuing alerts and warnings include attained and forecast river levels and rainfall in some rapidly responding locations. There are three levels of warning: Flood Alert, Flood Warning and Severe Flood Warning, and a stand down message. The warnings can be updated to include relevant information to help inform those at risk. Working with our current provider Fujitsu, the system is under a programme of continuous improvement including expanding the 'opt-out' service to mobile phone numbers registered to at risk addresses, allowing mobile registration to the system for people 'on the move' and providing access to registration via third parties. The 'Future Flood Warning System' Our research shows that people want more choice on how they access and receive warnings. Many want a service tailored to their own risk, rather than that of their community. They also want more information about the forecast and the situation to that they can make decisions personal to their circumstances. Our future flood warning system will build upon the success of our existing service and will aim to: • provide our customers with a more flexible and personalised self-service approach which caters for the diverse range of user needs • alert people wherever they are, not just in properties • be flexible enough to respond to user feedback to make improvements and utilise new technology as it becomes available • provide real-time visualisation of system performance, to assist our flood response • capture greater levels of information from the recipients of our warnings • be efficient for operators of the system and utilise automation where relevant • take a risk based approach to resilience to provide the highest level of reliability when needed at a reduced cost

  9. Stable carbon isotope labeling reveals different carry-over effects between functional types of tropical trees in an Ethiopian mountain forest.

    PubMed

    Krepkowski, Julia; Gebrekirstos, Aster; Shibistova, Olga; Bräuning, Achim

    2013-07-01

    We present an intra-annual stable carbon isotope (?(13)C) study based on a labeling experiment to illustrate differences in temporal patterns of recent carbon allocation to wood structures of two functional types of trees, Podocarpus falcatus (a late-successional evergreen conifer) and Croton macrostachyus (a deciduous broadleaved pioneer tree), in a tropical mountain forest in Ethiopia. Dendrometer data, wood anatomical thin sections, and intra-annual ?(13)C analyses were applied. Isotope data revealed a clear annual growth pattern in both studied species. For P. falcatus, it was possible to synchronize annual ?(13) C peaks, wood anatomical structures and monthly precipitation patterns. The labeling signature was evident for three consecutive years. For C. macrostachyus, isotope data illustrate a rapid decline of the labeling signal within half a year. Our ?(13)C labeling study indicates a distinct difference in carryover effects between trees of different functional types. A proportion of the labeled ?(13)C is stored in reserves of wood parenchyma for up to 3 yr in P. falcatus. By contrast, C. macrostachyus shows a high turnover of assimilates and a carbon carryover effect is only detectable in the subsequent year. PMID:23586968

  10. VLF emergency warning system for underground mines

    SciTech Connect

    Vanderlaag, J.H.; McDougall, J.S.

    1995-12-31

    An underground mine fire can seriously threaten the lives of all personnel in the mine. This fact makes fire emergency planning a high priority in the mining industry. The optimum warning alarm must be fast and able to reach all miners, regardless of their location or work activity. Current means of fire warning are varied, and include such methods as stench, telephones, and word-of-mouth (messengers). Unfortunately, none of these methods are entirely satisfactory. A novel fire warning alarm which enables instantaneous warning of all underground personnel, the Canary Mine Messenger System, has been developed by VLF Magnetic Systems Inc. in conjunction with Noranda Technology Centre and the U.S. Department of the Interior - Bureau of Mines. The warning is sent by an electromagnetic signal which penetrates through mine rock to receivers housed in the battery packs which also power each miner`s cap lamp. A loud buzzer in the integrated battery/receiver unit and the flashing of the cap lamp alerts miners to incoming messages. Testing of prototype equipment has demonstrated that the transmitted signal is capable of penetrating through over a mile of mine rock and activating the receiver. This report describes the theoretical basis for through-the-rock ultra-low frequency electromagnetic transmission, and the design of recently available transmitter and receivers.

  11. Laser labeling, a safe technology to label produce

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Laser labeling of fruits and vegetables is an alternative means to label produce. Low energy CO2 laser beams etch the surface showing the contrasting underlying layer. These etched surfaces can promote water loss and potentially allow for entry of decay organisms. The long-term effects of laser labe...

  12. 76 FR 75809 - Prior Label Approval System: Generic Label Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-05

    ... limited types of labels (e.g., labels for raw, single ingredient meat and poultry products) (48 FR 11410... products will take effect January 1, 2012 (75 FR 82148, Dec. 29, 2010). These mandatory features must be... Agency. On March 25, 1992, FSIS published an Advance Notice of Proposed Rulemaking (ANPRM) (57 FR...

  13. ForWarn Forest Disturbance Change Detection System Provides a Weekly Snapshot of US Forest Conditions to Aid Forest Managers

    NASA Astrophysics Data System (ADS)

    Hargrove, W. W.; Spruce, J.; Kumar, J.; Hoffman, F. M.

    2012-12-01

    The Eastern Forest Environmental Threat Assessment Center and Western Wildland Environmental Assessment Center of the USDA Forest Service have collaborated with NASA Stennis Space Center to develop ForWarn, a forest monitoring tool that uses MODIS satellite imagery to produce weekly snapshots of vegetation conditions across the lower 48 United States. Forest and natural resource managers can use ForWarn to rapidly detect, identify, and respond to unexpected changes in the nation's forests caused by insects, diseases, wildfires, severe weather, or other natural or human-caused events. ForWarn detects most types of forest disturbances, including insects, disease, wildfires, frost and ice damage, tornadoes, hurricanes, blowdowns, harvest, urbanization, and landslides. It also detects drought, flood, and temperature effects, and shows early and delayed seasonal vegetation development. Operating continuously since January 2010, results show ForWarn to be a robust and highly capable tool for detecting changes in forest conditions. To help forest and natural resource managers rapidly detect, identify, and respond to unexpected changes in the nation's forests, ForWarn produces sets of national maps showing potential forest disturbances at 231m resolution every 8 days, and posts the results to the web for examination. ForWarn compares current greenness with the "normal," historically seen greenness that would be expected for healthy vegetation for a specific location and time of the year, and then identifies areas appearing less green than expected to provide a strategic national overview of potential forest disturbances that can be used to direct ground and aircraft efforts. In addition to forests, ForWarn also tracks potential disturbances in rangeland vegetation and agriculural crops. ForWarn is the first national-scale system of its kind based on remote sensing developed specifically for forest disturbances. The ForWarn system had an official unveiling and rollout in March 2012, initiated by a joint NASA and USDA press release, and followed by a series of training webinars. Almost 60 early-adopter state and federal forest managers attended at least one of the ForWarn rollout webinars. The ForWarn home page has had 2,632 unique visitors since rollout in March 2012, with 39% returning visits. ForWarn was used to map tornado scars from the historic April 27, 2011 tornado outbreak, and detected timber damage within more than a dozen tornado tracks across northern Mississippi, Alabama, and Georgia. ForWarn is the result of an ongoing, substantive cooperation among four different government agencies: USDA, NASA, USGS, and DOE. Disturbance maps are available on the web through the ForWarn Change Assessment Viewer at http://forwarn.forestthreats.org/fcav.

  14. 33 CFR 183.514 - Fuel tanks: Labels.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...color of the label or be embossed on the label. (d) Each label must: (1) Withstand the combined effects of exposure to water, oil, salt spray, direct sunlight, heat, cold, and wear expected in normal operation of the boat, without...

  15. 33 CFR 183.514 - Fuel tanks: Labels.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...color of the label or be embossed on the label. (d) Each label must: (1) Withstand the combined effects of exposure to water, oil, salt spray, direct sunlight, heat, cold, and wear expected in normal operation of the boat, without...

  16. 75 FR 81943 - Appliance Labeling Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ...changing the effective date for its new light bulb labeling requirements (published...lamps,'' commonly referred to as light bulbs, and alternative labeling approaches...This document uses the terms lamp, light bulb, and bulb...

  17. Natural risk warning: comparison of two methodologies

    NASA Astrophysics Data System (ADS)

    Cavallo, A.; Giannoni, F.

    2005-05-01

    The Italian network of "Centri Funzionali" is now reaching operational status both in hydro-meteorological risk forecasting and support to the decision making of administrations that issue natural risk warning. Each centre operates for its district of influence. In order to have a nationwide common standard the National Civil Protection Department proposed a quantitative warning methodology based on the definition of rainfall thresholds correlated to historical damages. In the first phase the thresholds have been defined using two studies that cover all Italy: the VAPI (statistics of extreme rainfall and discharges, see reference) and the AVI (database of historical flood and landslide events and reported damages, see reference). This work presents one year back analysis that compares the new methodology and the one that has been usied since 2000 by the Liguria Region Meteorological Centre with regard to flood warning, pinpointing the performance differences in terms of false and missed alerts.

  18. A survey of early warning technologies

    SciTech Connect

    Smith, G.D.; Arlowe, H.D.; Williams, J.D.

    1995-07-01

    This paper presents a survey of technologies useful in providing early warning in physical security systems. Early warning is important in virtually all types of security systems whether they are used for temporary (tactical, portable, or semi-permanent) applications, border warning, fixed-site detection, or standoff surveillance detection. With the exception of the standoff surveillance detection systems, all systems discussed in this paper usually involve a moving target. The fact that a person(s) to be detected in a standoff surveillance scenario is not moving presents challenging problems and requires different applications of technology. The technologies commonly used to detect moving targets and some suggestions for detection of stationary targets are addressed in this paper.

  19. Influence of Variable Effect Radio-controlled LED Lighting Systems on Consumer Meat Display Perceptions from Display, Packaging, Labeling, and Lighting Interactions

    E-print Network

    Influence of Variable Effect Radio-controlled LED Lighting Systems on Consumer Meat Display retailers selling locally produced meat. Packaging and label modifications under these new LED light sources square-footage to beef products. To encourage consumers to purchase meat products, several tactics

  20. EFFECT OF RAPID SHALLOW BREATHING ON THE DISTRIBUTION OF 18-O-LABELED OZONE REACTION PRODUCT IN THE RESPIRATORY TRACT OF THE RAT

    EPA Science Inventory

    We examined the effect of breathing pattern on ozone reaction product content within the respiratory tract. Thirty-four anesthetized, maleWistar rats were exposed to oxygen-18 (18O)-labeled ozone at 1.0 ppm for 2 h using a dual-chamber, negative-pressure ventilation system. Fre...

  1. Effect of Micronutrients on Behavior and Mood in Adults with ADHD: Evidence from an 8-Week Open Label Trial with Natural Extension

    ERIC Educational Resources Information Center

    Rucklidge, Julia; Taylor, Mairin; Whitehead, Kathryn

    2011-01-01

    Objective: To investigate the effect of a 36-ingredient micronutrient formula consisting mainly of minerals and vitamins in the treatment of adults with both ADHD and severe mood dysregulation (SMD). Method: 14 medication-free adults (9 men, 5 women; 18-55 years) with ADHD and SMD completed an 8-week open-label trial. Results: A minority reported…

  2. [Effects of stable isotope labeled internal standard on determination of ivabradine and N-demethylivabradine in human plasma].

    PubMed

    Liu, Dong-qin; Yu, Jing-hua; Zhang, Yi-fan; Zhong, Da-fang; He, Ling; Chen, Xiao-yan

    2015-03-01

    This study aims to develop a liquid chromatography with tandem mass spectrometry (LC-MS/MS) method for the simultaneous determination of ivabradine and N-demethylivabradine in human plasma, and investigate effects of stable isotope labeled (SIL) internal standard (IS) on ivabradine. The analytes and IS were extracted from plasma by protein precipitation with acetonitrile, and chromatographied on a Capcell PAK C18 (100 mm x 4.6 mm, 5 ?m) column using a mobile phase of methanol and 5 mmol x L(-1) ammonium acetate. Multiple reaction monitoring with electrospray ionization (ESI) was used in the positive mode for mass spectrometric detection. The effect of ivabradine isotope peak [M+H+3] + on IS and the effect of SIL IS purity on ivabradine were evaluated. An appropriate concentration of SIL IS was chosen to permit method selectivity and linearity of the assay over the required range. The standard curves were demonstrated to be linear in the range of 0.100 to 60.0 ng x mL(-1) for ivabradine, and 0.050 0 to 20.0 ng x mL(-1) for N-demethylivabradine. The intra and inter day precision and accuracy were within the acceptable limits for all concentrations. Besides, the interaction between IS and ivabradine did not impact the determination of analytes. This method was successfully applied to a pharmacokinetic study of hydrogen sulfate ivabradine sustained release tablets on Chinese healthy volunteers. PMID:26118116

  3. Mobile machine hazardous working zone warning system

    DOEpatents

    Schiffbauer, William H. (Connellsville, PA); Ganoe, Carl W. (Pittsburgh, PA)

    1999-01-01

    A warning system is provided for a mobile working machine to alert an individual of a potentially dangerous condition in the event the individual strays into a hazardous working zone of the machine. The warning system includes a transmitter mounted on the machine and operable to generate a uniform magnetic field projecting beyond an outer periphery of the machine in defining a hazardous working zone around the machine during operation thereof. A receiver, carried by the individual and activated by the magnetic field, provides an alarm signal to alert the individual when he enters the hazardous working zone of the machine.

  4. Mobile machine hazardous working zone warning system

    DOEpatents

    Schiffbauer, W.H.; Ganoe, C.W.

    1999-08-17

    A warning system is provided for a mobile working machine to alert an individual of a potentially dangerous condition in the event the individual strays into a hazardous working zone of the machine. The warning system includes a transmitter mounted on the machine and operable to generate a uniform magnetic field projecting beyond an outer periphery of the machine in defining a hazardous working zone around the machine during operation. A receiver, carried by the individual and activated by the magnetic field, provides an alarm signal to alert the individual when he enters the hazardous working zone of the machine. 3 figs.

  5. Sensors Provide Early Warning of Biological Threats

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Early Warning Inc. of Troy, New York, licensed powerful biosensor technology from Ames Research Center. Incorporating carbon nanotubes tipped with single strands of nucleic acid from waterborne pathogens, the sensor can detect even minute amounts of targeted, disease causing bacteria, viruses, and parasites. Early Warning features the NASA biosensor in its water analyzer, which can provide advance alert of potential biological hazards in water used for agriculture, food and beverages, showers, and at beaches and lakes -- within hours instead of the days required by conventional laboratory methods.

  6. Attitudes and preferences of consumers toward food allergy labeling practices by diagnosis of food allergies

    PubMed Central

    Ju, Se-young; Park, Jong-Hwan; Kim, Kyu-earn

    2015-01-01

    BACKGROUND/OBJECTIVES The objective of this study was to investigate food allergens and prevalence rates of food allergies, followed by comparison of consumer attitudes and preferences regarding food allergy labeling by diagnosis of food allergies. SUBJECTS/METHODS A total of 543 individuals living in Seoul and Gyeonggi area participated in the survey from October 15 to 22 in 2013. RESULTS The results show that the prevalence of doctor-diagnosed food allergies was 17.5%, whereas 6.4% of respondents self-reported food allergies. The most common allergens of doctor-diagnosed and self-reported food allergy respondents were peaches (30.3%) and eggs (33.3%), respectively, followed by peanuts, cow's milk, and crab. Regarding consumer attitudes toward food labeling, checking food allergens as an item was only significantly different between allergic and non-allergic respondents among all five items (P < 0.001). All respondents reported that all six items (bold font, font color, box frame, warning statement, front label, and addition of potential allergens) were necessary for an improved food allergen labeling system. PLSR analysis determined that the doctor-diagnosed group and checking of food allergens were positively correlated, whereas the non-allergy group was more concerned with checking product brands. CONCLUSIONS An effective food labeling system is very important for health protection of allergic consumers. Additionally, government agencies must develop policies regarding prevalence of food allergies in Korea. Based on this information, the food industry and government agencies should provide clear and accurate food labeling practices for consumers. PMID:26425282

  7. 21 CFR 201.308 - Ipecac syrup; warnings and directions for use for over-the-counter sale.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...conspicuous manner: (1) A statement conspicuously boxed and in red letters, to the effect: “For emergency use to cause vomiting...physician, the Poison Control Center, or hospital emergency room immediately for advice.” (2) A warning to the...

  8. Integrating automobile multiple intelligent warning systems : performance and policy implications

    E-print Network

    Ho, Angela Wei Ling

    2006-01-01

    Intelligent driver warning systems can be found in many high-end vehicles on the road today, which will likely rapidly increase as they become standard equipment. However, introducing multiple warning systems into vehicles ...

  9. Early Warning Sign for Kidney Disease Identified in Study

    MedlinePLUS

    ... news/fullstory_155546.html Early Warning Sign for Kidney Disease Identified in Study Researchers say blood test ... ve discovered an early warning sign of chronic kidney disease. They found that levels of a common ...

  10. 46 CFR 108.626 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...2012-10-01 2012-10-01 false Carbon dioxide warning signs. 108.626 ...Markings and Instructions § 108.626 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  11. 46 CFR 196.37-8 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 2013-10-01 false Carbon dioxide warning signs. 196.37-8...Emergency Equipment, etc. § 196.37-8 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  12. 46 CFR 97.37-11 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 2013-10-01 false Carbon dioxide warning signs. 97.37-11...Emergency Equipment, Etc. § 97.37-11 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  13. 46 CFR 131.817 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...2012-10-01 2012-10-01 false Carbon dioxide warning signs. 131.817 ...and Emergency Equipment § 131.817 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  14. 46 CFR 108.626 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 2013-10-01 false Carbon dioxide warning signs. 108.626 ...Markings and Instructions § 108.626 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  15. 46 CFR 108.626 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 2014-10-01 false Carbon dioxide warning signs. 108.626 ...Markings and Instructions § 108.626 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  16. 46 CFR 97.37-11 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 2014-10-01 false Carbon dioxide warning signs. 97.37-11...Emergency Equipment, Etc. § 97.37-11 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  17. 46 CFR 196.37-8 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...2012-10-01 2012-10-01 false Carbon dioxide warning signs. 196.37-8...Emergency Equipment, etc. § 196.37-8 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  18. 46 CFR 196.37-8 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 2014-10-01 false Carbon dioxide warning signs. 196.37-8...Emergency Equipment, etc. § 196.37-8 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  19. 46 CFR 131.817 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 2013-10-01 false Carbon dioxide warning signs. 131.817 ...and Emergency Equipment § 131.817 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  20. 46 CFR 97.37-11 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...2012-10-01 2012-10-01 false Carbon dioxide warning signs. 97.37-11...Emergency Equipment, Etc. § 97.37-11 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  1. 46 CFR 78.47-11 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...2012-10-01 2012-10-01 false Carbon dioxide warning signs. 78.47-11...Emergency Equipment, Etc. § 78.47-11 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  2. 46 CFR 131.817 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 2014-10-01 false Carbon dioxide warning signs. 131.817 ...and Emergency Equipment § 131.817 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  3. 46 CFR 78.47-11 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 2013-10-01 false Carbon dioxide warning signs. 78.47-11...Emergency Equipment, Etc. § 78.47-11 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  4. 46 CFR 78.47-11 - Carbon dioxide warning signs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 2014-10-01 false Carbon dioxide warning signs. 78.47-11...Emergency Equipment, Etc. § 78.47-11 Carbon dioxide warning signs. Each entrance to a space storing carbon dioxide cylinders, a space...

  5. 30 CFR 27.23 - Automatic warning device.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...PRODUCTS METHANE-MONITORING SYSTEMS Construction and Design Requirements § 27.23 Automatic warning device...permissible and approved equipment that is operated in gassy mines and tunnels. (b) An automatic warning device shall include...

  6. 47 CFR 95.653 - Instructions and warnings.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...representative of users of those services. (3) Warnings concerning the replacement of any transmitter component (crystal, semiconductor, etc.) that could result in a violation of the rules. (4) For a CMRS transmitter, warnings concerning...

  7. 47 CFR 95.653 - Instructions and warnings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...representative of users of those services. (3) Warnings concerning the replacement of any transmitter component (crystal, semiconductor, etc.) that could result in a violation of the rules. (4) For a CMRS transmitter, warnings concerning...

  8. 47 CFR 95.653 - Instructions and warnings.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...representative of users of those services. (3) Warnings concerning the replacement of any transmitter component (crystal, semiconductor, etc.) that could result in a violation of the rules. (4) For a CMRS transmitter, warnings concerning...

  9. 47 CFR 95.653 - Instructions and warnings.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...representative of users of those services. (3) Warnings concerning the replacement of any transmitter component (crystal, semiconductor, etc.) that could result in a violation of the rules. (4) For a CMRS transmitter, warnings concerning...

  10. 14 CFR 135.154 - Terrain awareness and warning system.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...14 Aeronautics and Space 3 2014-01-01...2014-01-01 false Terrain awareness and warning system...154 Aeronautics and Space FEDERAL AVIATION...135.154 Terrain awareness and warning system...an approved terrain situational awareness...

  11. 14 CFR 135.154 - Terrain awareness and warning system.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...14 Aeronautics and Space 3 2013-01-01...2013-01-01 false Terrain awareness and warning system...154 Aeronautics and Space FEDERAL AVIATION...135.154 Terrain awareness and warning system...an approved terrain situational awareness...

  12. 14 CFR 121.354 - Terrain awareness and warning system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...14 Aeronautics and Space 3 2012-01-01...2012-01-01 false Terrain awareness and warning system...354 Aeronautics and Space FEDERAL AVIATION...121.354 Terrain awareness and warning system...an approved terrain situational awareness...

  13. 14 CFR 121.354 - Terrain awareness and warning system.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...14 Aeronautics and Space 3 2013-01-01...2013-01-01 false Terrain awareness and warning system...354 Aeronautics and Space FEDERAL AVIATION...121.354 Terrain awareness and warning system...an approved terrain situational awareness...

  14. 14 CFR 135.154 - Terrain awareness and warning system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...14 Aeronautics and Space 3 2012-01-01...2012-01-01 false Terrain awareness and warning system...154 Aeronautics and Space FEDERAL AVIATION...135.154 Terrain awareness and warning system...an approved terrain situational awareness...

  15. 14 CFR 121.354 - Terrain awareness and warning system.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...14 Aeronautics and Space 3 2014-01-01...2014-01-01 false Terrain awareness and warning system...354 Aeronautics and Space FEDERAL AVIATION...121.354 Terrain awareness and warning system...an approved terrain situational awareness...

  16. Missile Warning Operations Center (MWOC) Beale Air Force Base, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Missile Warning Operations Center (MWOC) - Beale Air Force Base, Perimeter Acquisition Vehicle Entry Phased-Array Warning System, Techinical Equipment Building, End of Spencer Paul Road, north of Warren Shingle Road (14th Street), Marysville, Yuba County, CA

  17. Ballistic Missile Early Warning System Clear Air Force Station, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Ballistic Missile Early Warning System - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  18. Effect of freezing conditions on distances and their distributions derived from Double Electron Electron Resonance (DEER): A study of doubly-spin-labeled T4 lysozyme

    NASA Astrophysics Data System (ADS)

    Georgieva, Elka R.; Roy, Aritro S.; Grigoryants, Vladimir M.; Borbat, Petr P.; Earle, Keith A.; Scholes, Charles P.; Freed, Jack H.

    2012-03-01

    Pulsed dipolar ESR spectroscopy, DEER and DQC, require frozen samples. An important issue in the biological application of this technique is how the freezing rate and concentration of cryoprotectant could possibly affect the conformation of biomacromolecule and/or spin-label. We studied in detail the effect of these experimental variables on the distance distributions obtained by DEER from a series of doubly spin-labeled T4 lysozyme mutants. We found that the rate of sample freezing affects mainly the ensemble of spin-label rotamers, but the distance maxima remain essentially unchanged. This suggests that proteins frozen in a regular manner in liquid nitrogen faithfully maintain the distance-dependent structural properties in solution. We compared the results from rapidly freeze-quenched (?100 ?s) samples to those from commonly shock-frozen (slow freeze, 1 s or longer) samples. For all the mutants studied we obtained inter-spin distance distributions, which were broader for rapidly frozen samples than for slowly frozen ones. We infer that rapid freezing trapped a larger ensemble of spin label rotamers; whereas, on the time-scale of slower freezing the protein and spin-label achieve a population showing fewer low-energy conformers. We used glycerol as a cryoprotectant in concentrations of 10% and 30% by weight. With 10% glycerol and slow freezing, we observed an increased slope of background signals, which in DEER is related to increased local spin concentration, in this case due to insufficient solvent vitrification, and therefore protein aggregation. This effect was considerably suppressed in slowly frozen samples containing 30% glycerol and rapidly frozen samples containing 10% glycerol. The assignment of bimodal distributions to tether rotamers as opposed to protein conformations is aided by comparing results using MTSL and 4-Bromo MTSL spin-labels. The latter usually produce narrower distance distributions.

  19. Rapid telemetry and earthquake early warning

    NASA Astrophysics Data System (ADS)

    Allen, R.; Bose, M.; Brown, H.; Cua, G.; Given, D.; Hauksson, E.; Heaton, T.; Hellweg, M.; Jordan, T.; Kireev, A.; Maechling, P.; Neuhauser, D.; Oppenheimer, D.; Solanki, K.; Zeleznik, M.

    2008-05-01

    The California Integrated Seismic Network (CISN) is currently testing algorithms for earthquake early warning on the realtime seismic systems in the state. An earthquake warning system rapidly detects the initiation of earthquakes and assesses the associated hazard. The goal is to provide warning of potentially damaging ground motion in a target region prior to the arrival of seismic waves. The network-based approach to early warning requires station data to be gathered at a central site for joint processing. ElarmS, one network-based approach being tested, currently runs 15 sec behind realtime in order to gather ~90% of station data before processing. Even with this delay the recent Mw 5.4 Alum Rock earthquake near San Jose was detected and an accurate hazard assessment was available before ground shaking in San Francisco. The Virtual Seismologist (VS) method, another network-based approach, is a Bayesian method that incorporates information such as network topology, previously observed seismicity, and the Gutenberg-Richter relationship in magnitude and location estimation. The VS method is currently being transitioned from off-line to real-time testing and will soon be running 15 sec behind real-time, as in the case of ElarmS. We are also testing an on-site warning approach, which is based on single-station observations. On-site systems can deliver earthquake information faster than regional systems, and the warning could possibly reach potential users at much closer epicentral distances before the damaging shaking starts. By definition, on-site systems do not require a central processing facility or delivery of data from a distant seismic station, but they are less robust that networked-based systems and need a fast and reliable telemetry to deliver warnings to local users. The range of possible warning times is typically seconds to tens of seconds and every second of data latency translates into an equal reduction in the available warning time. Minimal latency is therefore important to warning systems. Sources of latency range from data packetization in the digitizer system through telemetry systems to processing at the data (warning) center. As part of the ongoing testing in California, we are assessing the data latencies for the various generations of geophysical equipment currently in use, and find that one large source of delay is the packetization of data by dataloggers prior to transmission. We are also assessing delays caused within telemetry systems ranging from satellite connections through radio, frame relay, cell phone data services and publicly available internet services such as DSL. We are investigating ways to reduce the current delays and formulating specifications for the next generation of geophysical networks that will provide realtime data in a robust fashion.

  20. Safety Early Warning Research for Highway Construction Based on Case-Based Reasoning and Variable Fuzzy Sets

    PubMed Central

    Liu, Yan; Xu, Zhen-Jun

    2013-01-01

    As a high-risk subindustry involved in construction projects, highway construction safety has experienced major developments in the past 20 years, mainly due to the lack of safe early warnings in Chinese construction projects. By combining the current state of early warning technology with the requirements of the State Administration of Work Safety and using case-based reasoning (CBR), this paper expounds on the concept and flow of highway construction safety early warnings based on CBR. The present study provides solutions to three key issues, index selection, accident cause association analysis, and warning degree forecasting implementation, through the use of association rule mining, support vector machine classifiers, and variable fuzzy qualitative and quantitative change criterion modes, which fully cover the needs of safe early warning systems. Using a detailed description of the principles and advantages of each method and by proving the methods' effectiveness and ability to act together in safe early warning applications, effective means and intelligent technology for a safe highway construction early warning system are established. PMID:24191134

  1. Clinical Assessment of the Effect of Tetrabenazine on Functional Scales in Huntington Disease: A Pilot Open Label Study

    PubMed Central

    Fekete, Robert; Davidson, Anthony; Jankovic, Joseph

    2012-01-01

    Background Tetrabenazine is a monoamine depleter with a well-documented effect against chorea associated with Huntington disease (HD). There is a paucity of data about how reduction in chorea relates to better performance on motor, gait, cognitive, and psychiatric assessments. Methods We designed an open label tetrabenazine withdrawal study to test performance using validated scales. The following instruments were used to assess cognitive, behavioral, and motor function in 10 patients with documented HD: The Montreal Cognitive Assessment, Beck Depression Inventory II, Dynamic Gait Index (DGI), Jebsen Hand Test, Timed 25-foot walk, Berg Balance Test (BBT), QuickDASH, and the Unified Huntington Disease Rating Scale (UHDRS) Motor, Stroop Color Word, Behavioral Assessment, Functional Checklist, and Independence Scale. Results Subjects performed significantly better while on tetrabenazine as measured by the DGI (p?=?0.041), BBT (p?=?0.007), and the UHDRS Total Motor (p?=?0.009), Maximum Chorea (p?=?0.005), and Stroop Color-Word tests (p?=?0.028). Discussion This pilot study demonstrates tetrabenazine's potential effects beyond improvement in chorea. PMID:23439575

  2. 14 CFR 91.603 - Aural speed warning device.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aural speed warning device. 91.603 Section... Operating Requirements for Large and Transport Category Aircraft § 91.603 Aural speed warning device. No... aural speed warning device that complies with § 25.1303(c)(1)....

  3. 33 CFR 143.15 - Lights and warning devices.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Lights and warning devices. 143... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT General § 143.15 Lights and warning devices. (a) OCS facilities must meet the lights and warning devices requirements under part 67 of...

  4. 33 CFR 143.15 - Lights and warning devices.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Lights and warning devices. 143... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT General § 143.15 Lights and warning devices. (a) OCS facilities must meet the lights and warning devices requirements under part 67 of...

  5. 33 CFR 143.15 - Lights and warning devices.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Lights and warning devices. 143... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT General § 143.15 Lights and warning devices. (a) OCS facilities must meet the lights and warning devices requirements under part 67 of...

  6. 33 CFR 143.15 - Lights and warning devices.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Lights and warning devices. 143... (CONTINUED) OUTER CONTINENTAL SHELF ACTIVITIES DESIGN AND EQUIPMENT General § 143.15 Lights and warning devices. (a) OCS facilities must meet the lights and warning devices requirements under part 67 of...

  7. Improving SSL Warnings: Comprehension and Adherence Adrienne Porter Felt1

    E-print Network

    Cortes, Corinna

    Google, 2 University of Pennsylvania 1 {felt, ainslie, rreeder, sconsolvo, somast, bettes, helenharris}@google warn- ing. We attribute this success to opinionated design, which promotes safety with visual cues. Subsequently, our proposal was released as the new Google Chrome SSL warning. We raise questions about warning

  8. One-Year-Olds Warn Others about Negative Action Outcomes

    ERIC Educational Resources Information Center

    Knudsen, Birgit; Liszkowski, Ulf

    2013-01-01

    Warning others is a paradigm case of communicative helping and prospective action understanding. The current study addressed the ontogeny of warning in infants' gestural communication. We found that 12- and 18-month-olds ("n" = 84) spontaneously warned an adult by pointing out to her an aversive object hidden in her way…

  9. 21 CFR 330.2 - Pregnancy-nursing warning.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...2014-04-01 2014-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food... General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning for OTC drugs is set forth under §...

  10. 21 CFR 330.2 - Pregnancy-nursing warning.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...2013-04-01 2013-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food... General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning for OTC drugs is set forth under §...

  11. 21 CFR 330.2 - Pregnancy-nursing warning.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...2010-04-01 2010-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food... General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning for OTC drugs is set forth under §...

  12. 21 CFR 330.2 - Pregnancy-nursing warning.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...2011-04-01 2011-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food... General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning for OTC drugs is set forth under §...

  13. 21 CFR 330.2 - Pregnancy-nursing warning.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...2012-04-01 2012-04-01 false Pregnancy-nursing warning. 330.2 Section 330.2 Food... General Provisions § 330.2 Pregnancy-nursing warning. A pregnancy-nursing warning for OTC drugs is set forth under §...

  14. 14 CFR 121.289 - Landing gear: Aural warning device.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Landing gear: Aural warning device. 121.289... gear: Aural warning device. (a) Except for airplanes that comply with the requirements of § 25.729 of this chapter on or after January 6, 1992, each airplane must have a landing gear aural warning...

  15. 14 CFR 121.289 - Landing gear: Aural warning device.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Landing gear: Aural warning device. 121.289... gear: Aural warning device. (a) Except for airplanes that comply with the requirements of § 25.729 of this chapter on or after January 6, 1992, each airplane must have a landing gear aural warning...

  16. Electrical Distribution System (EDS) and Caution and Warning System (CWS)

    NASA Technical Reports Server (NTRS)

    Mcclung, T.

    1975-01-01

    An astronaut caution and warning system is described which monitors various life support system parameters and detects out-of-range parameter conditions. The warning system generates a warning tone and displays the malfunction condition to the astronaut along with the proper corrective procedures required.

  17. 40 CFR 82.108 - Placement of warning statement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Placement of warning statement. 82.108....108 Placement of warning statement. The warning statement shall be placed so as to satisfy the... placement includes, but is not limited to, the following: (a) Display panel placement. For any...

  18. 40 CFR 82.108 - Placement of warning statement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Placement of warning statement. 82.108....108 Placement of warning statement. The warning statement shall be placed so as to satisfy the... placement includes, but is not limited to, the following: (a) Display panel placement. For any...

  19. 40 CFR 82.108 - Placement of warning statement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Placement of warning statement. 82.108....108 Placement of warning statement. The warning statement shall be placed so as to satisfy the... placement includes, but is not limited to, the following: (a) Display panel placement. For any...

  20. 40 CFR 82.108 - Placement of warning statement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Placement of warning statement. 82.108....108 Placement of warning statement. The warning statement shall be placed so as to satisfy the... placement includes, but is not limited to, the following: (a) Display panel placement. For any...