Sample records for ejercicio como factor

  1. Estadistica II Ejercicios Tema 3

    E-print Network

    Gil, Ana Arribas

    contraste oportuno, especificando claramente la hip´otesis nula y alternativa que con- sideras. b) Calcula %, especificando claramente la hip´otesis nula y alternativa que consideras, as´i como las hip´otesis de trabajo. b = 0,01? Plantea el contraste oportuno especificando claramente la hip´otesis nula y alternativa que

  2. LA INNOVACIN COMO FACTOR DE CALIDAD EN LAS ORGANIZACIONES EDUCATIVAS (INNOVATION AS A QUALITY FACTOR IN EDUCATIONAL ORGANIZATIONS)

    Microsoft Academic Search

    Jos Fernndez Daz

    2005-01-01

    This paper studies the role of innovation as a fundamental factor in the qualty of educato- nal organizations, as it is considered in several qualty models, such as the EFQM. A better understanding of the process of innovation is seeked looking at the relatonshp and dfferen- ces between innovation and change. The paper focuses on the factors and condtions of

  3. Departamento de Matemticas Matemticas (CC. Qumicas) Ejercicios sobre derivacin: representacin de funciones.

    E-print Network

    : representacin de funciones. En los siguientes ejercicios se pide representar una serie de funciones. Puedes usar siguientes funciones en los conjuntos que se indica. Mo- tivos tcnicos impiden numerar los ejercicios de funciones en los conjuntos que se indica. Mo- tivos tcnicos impider numerar los ejercicios de forma normal

  4. El hogar como un contexto sociocultural de prcticas de lectoescritura de inmigrantes mexicanos en Canad

    Microsoft Academic Search

    Maria Eugenia De Luna Villaln

    2009-01-01

    El propsito de este estudio es investigar, describir y explicar cules son las prcticas de lectoescritura en el hogar de cuatro familias mexicanas inmigrantes en Canad; conocer la interrelacin de las prcticas de lectoescritura en el hogar y las prcticas de lectoescritura escolar; el papel que juega la familia como mediadora en el ejercicio de las prcticas de lectoescritura y

  5. Teoria analitica de numeros Capitulo 2. Funciones aritmeticas. Ejercicios 2007-2008

    E-print Network

    Miana, Pedro J.

    Teoria analitica de numeros Capitulo 2. Funciones aritmeticas. Ejercicios 2007-2008 1.- Completar el cuadrado de caracteristicas ( funciones multiplicativas y completamente multiplicativas) de las funciones aritmeticas , , N , u, , , , , , r, , , , ( R) definidas en este capitulo. 2.- (i

  6. EL ABOGADO DEL NIO COMO GARANTE DEL PLENO EJERCICIO DE LOS DERECHOS DE LOS MENORES DE EDAD

    Microsoft Academic Search

    Lisbeth Rodrguez Martn; Yanelys Palmero Martn

    2012-01-01

    El tratamiento de la niez y sus derechos resulta tema de inters universal para las ciencias jurdicas modernas, debido a las nuevas tendencias de proteccin surgidas a partir de la celebracin de los Congresos Panamericanos del Nio y la Convencin sobre los Derechos del Nio. De modo, que para las ciencias jurdicas cubanas se hace de suma importancia el estudio

  7. Factoring

    NSDL National Science Digital Library

    Mr Clark

    2012-10-31

    Test your factoring skills Factors and Multiples Jeopardy How much do you know about factoring and multiples? Play Jeopardy and find out! Prime Factoring Turkey Shoot Blast these turkeys using your factoring skills. Help the Professor Super save the planet by "cooking" the Giant Frozen Turkeys of Destruction. Math Lines 12 X-Factor Shoot the ball at the other factors to get a product of 12. You can also ...

  8. Factoring

    NSDL National Science Digital Library

    Mrs. Taylor

    2010-10-19

    In this lesson we will explore prime numbers and factors A prime number has only two factors, 1 and itself. The Greek scholar, Eratosthenes of Cyrene lived from approximately 275 to 195 BC. He is know for being the first to have computed the size of the Earth and served as the director of the famous library in

  9. Factorize

    NSDL National Science Digital Library

    2010-01-01

    In this activity, students find factor pairs for a given number and then create a rectangle with those dimensions on a coordinate plane. This activity allows students to explore factorizations of numbers and how they relate to rectangles with that number as an area. This activity includes supplemental materials, including background information about the topics covered, a description of how to use the application, and exploration questions for use with the java applet.

  10. Pedagogical Factors That Influence EFL Teaching: Some Considerations for Teachers' Professional Development (Factores pedaggicos que influyen en la enseanza del ingls como lengua extranjera: algunas consideraciones para el desarrollo profesional de docentes)

    ERIC Educational Resources Information Center

    Abad, Jos Vicente

    2013-01-01

    In this article we present the results of a qualitative research study on the pedagogical factors that influence English teaching in four public schools of Medelln, Colombia. Twelve teachers were interviewed regarding three linguistic principles: communicative competence, native language effect, and interlanguage. The data analysis led to the

  11. TUBERCULOSIS COMO ENFERMEDAD OCUPACIONAL

    PubMed Central

    Mendoza-Ticona, Alberto

    2014-01-01

    Existe evidencia suficiente para declarar a la tuberculosis como enfermedad ocupacional en diversos profesionales especialmente entre los trabajadores de salud. En el Per estn normados y reglamentados los derechos laborales inherentes a la tuberculosis como enfermedad ocupacional, como la cobertura por discapacidad temporal o permanente. Sin embargo, estos derechos an no han sido suficientemente socializados. En este trabajo se presenta informacin sobre el riesgo de adquirir tuberculosis en el lugar de trabajo, se revisan las evidencias para declarar a la tuberculosis como enfermedad ocupacional en trabajadores de salud y se presenta la legislacin peruana vigente al respecto. PMID:22858771

  12. Banca y medio ambiente. Un ejercicio de responsabilidad social empresarial. Volumen I

    Microsoft Academic Search

    Oscar Daro Amaya Navas; ngela Mara Amaya Arias

    Este libro identifica elementos centrales del concepto de responsabilidad social empresarial con el fin de analizar temas como el ambientalismo corporativo, la banca tica y la ecoeficiencia, explicando claramente la manera en que estos conceptos son aplicables a la gestin bancaria mediante la implementacin de polticas y decisiones que fomenten el equilibrio entre rentabilidad econmica y desarrollo sostenible.Los autores exponen

  13. Ejercicio 11: a) Nmero de funciones de {1,...,n} en {1,...,m} tales que f(i)

    E-print Network

    Meza, Oscar J.

    Ejercicio 11: a) Número de funciones de {1,...,n} en {1,...,m} tales que f(i),j en {1,...n} y ifunciones estrictamente crecientes de {1,...,n esto). Así el número de funciones estrictamente crecientes es , por principio de igualdad, igual a

  14. La posesin como hecho punible

    Microsoft Academic Search

    Friedrich Christian Schroeder

    Este trabajo estudia el delito de posesin, el cual se extiende semnticamente hasta trminos como custodia, mantener disponible, almacenar, etc., y como conminada con la pena se halla la posesin de explosivos, de armas de fuego, de drogas, de pornografa infantil, etc. En este mismo trabajo se analizan, bajo la ptica del Cdigo Penal alemn, cmo las acciones graves o

  15. LA BIOTICA COMO QUEHACER FILOSFICO

    PubMed Central

    Ferrer, Jorge Jos

    2009-01-01

    El artculo examina el estatuto epistemolgico de la biotica como disciplina acadmica. El autor sostiene que el estatuto epistemolgico de un discurso lo determina la pregunta fundamental que se plantea y la respuesta que se busca, focos integradores del discurso. En el caso de la biotica, la pregunta fundamental es de ndole moral. La biotica es pues una disciplina tica que tiene su hogar epistemolgico en la filosofa. El autor tambin defiende el concepto de ticas aplicadas. Sugiere finalmente que el mtodo de la biotica, sobre todo la que se hace desde nuestras latitudes, debera adoptar el crculo hermenutico como metodologa para su filosofar. PMID:20463860

  16. Como Lo Hago Yo: Myelomeningocele

    PubMed Central

    Lazareff, Jorge

    2014-01-01

    Fortificacin con dico flico es efectiva, pero an falta conciencia en los jvenes. La legalidad del aborto aumenta la importancia de la consulta prenatal. Realizo la ciruga bajo microcoscopio por razones didcticas. Irrigacin continua para reducir la temperatura del tejido. Trato a la plaqueta como tejido viable. No suturo la plaqueta. No cierro msculo. ATB por una semana despus de ciruga. Hidrocefalia: Vlvula en todos los casos de ventriculomegalia. Mdula anclada: Desanclar una sola vez. Chiari II: Revisar la vlvula. Incluir en el seguimiento rendimiento escolar, puede indicar obstruccin de la vlvula o mdula anclada. PMID:24791217

  17. Factor Trees

    NSDL National Science Digital Library

    Math Playground

    2009-07-29

    This virtual manipulative allows students to find the prime factorization of numbers by completing factor trees. Then they may use a venn diagram to sort the prime factors to find the greatest common factor and the least common multiple.

  18. Factor Trees

    NSDL National Science Digital Library

    2010-01-01

    In this online activity, the learner finds the prime factorization of composite numbers by building factor trees. A second level includes finding the greatest common factor and the least common multiple by sorting factors using a Venn Diagram.

  19. Factoring with the Factor Tree

    NSDL National Science Digital Library

    Interactive Math Miscellany and Puzzles, Alexander Bogomolny

    2011-01-01

    This Java applet presents a composite number, and prompts you to factor it -- one step at a time. Enter one factor, prime or another composite; the applet calculates the remaining factor, and branches two boxes below any composite factor so that you may proceed factoring until you obtain the full factorization into primes, which the applet colors in green. Click the "Repeat problem" button to see that different factor trees for a given number still result in the same prime factorization.

  20. Factor Oracles

    Microsoft Academic Search

    Maxime Crochemore; Lucian Ilie; Emine Seid-hilmi

    2006-01-01

    The factor oracle is a relatively new data structure for the set of factors of a string which has been introduced by Allauzen,\\u000a Crochemore, and Raffinot in 1999. It may recognize non-factors (hence the name oracle) but its implementational simplicity\\u000a and experimental behaviour are stunning; factor oracle based string matching has been conjectured optimal on average. However,\\u000a its structure is

  1. Factor Game

    NSDL National Science Digital Library

    National Council of Teachers of Mathematics

    2009-07-22

    The Factor Game engages students in a contest in which winning strategies involve distinguishing between numbers with many factors and numbers with few factors. Students are then guided through an analysis of game strategies and introduced to the definitions of prime and composite numbers.

  2. Factor Findings

    NSDL National Science Digital Library

    Jamie Piecora

    2000-01-01

    In this lesson, students first create factor posters for a variety of different numbers that will be displayed in the classroom to be utilized as a resource throughout the school year. They make discoveries about factors using color tiles, represent their discoveries using graph paper, and display their information on poster board as find factors of an assigned number. The plan includes a list of materials, questions, assessment options, and extensions.

  3. Apoyo social como factor protector frente a la violencia contra la mujer en la pareja

    Microsoft Academic Search

    Juncal Plazaola-Castao; Isabel Ruiz-Prez; Mara Isabel Montero-Piar

    2008-01-01

    ObjectiveTo describe the relationship between the presence of social support and overall support from different sources and intimate partner violence in women attending primary care centers irrespective of reason.

  4. Factor Dazzle

    NSDL National Science Digital Library

    2011-01-01

    This interactive online game helps students develop fluency with identifying factors while fostering strategic thinking. A student can play against the computer or against a friend on a 6 by 6 grid containing the numbers 1-36. Each player in turn chooses a number from the board, and then the opponent claims all of its remaining proper factors. A player's score is the sum of all the numbers and factors she/he has chosen. When there are no numbers remaining with unclaimed factors, the game ends and the player with the greater total is the winner. This game is part of NCTM's Calculation Nation project (cataloged separately). Users may login as a guest and play against the computer, or register (free) to challenge other players online.

  5. Las regiones Objetivo 1 espaolas en la sociedad de la informacin: el comercio electrnico como elemento de desarrollo

    Microsoft Academic Search

    Enrique Bernal Jurado; Juan Carlos Rodrguez Cohard

    2003-01-01

    RESUMEN Las tecnologas de la informacin y comunicacin (TIC) constituyen una de las principales fuerzas de la globalizacin. El comercio electrnico aprovecha Internet para mejorar la competitividad de las empresas y territorios. En un escenario como el actual, este canal, por un lado, abre posibilidades de desarrollo para las regiones Objetivo 1, pero, por otro, refuerza los factores de crecimiento

  6. Factor Track

    NSDL National Science Digital Library

    This problem helps learners improve their knowledge of factors, especially those in the usual multiplication tables, and encourages the problem solving strategy of trial and error. The goal of the game is to go around the track in as few moves as possible, keeping to the rules that a player can move any number of spaces which is a factor of the number the player is on, except 1. There is a "training" track to play on initially to see the rules in action and then a more complicated track for players to use. The Teachers' Notes page offers suggestions for implementation, key discussion questions, ideas for extension and support.

  7. Bayes Factors

    Microsoft Academic Search

    Robert E. Kass; Adrian E. Raftery

    1995-01-01

    In a 1935 paper and in his book Theory of Probability, Jeffreys developed a methodology for quantifying the evidence in favor of a scientific theory. The centerpiece was a number, now called the Bayes factor, which is the posterior odds of the null hypothesis when the prior probability on the null is one-half. Although there has been much discussion of

  8. Thrombopoietin Factors

    Microsoft Academic Search

    Ping Wei

    \\u000a Megakaryopoiesis and thrombopoiesis are the central biological processes of platelet generation. Severe thrombocytopenia is\\u000a a major morbidity and mortality factor in several diseases and represents a significant unmet medical need. Since the discovery\\u000a of thrombopoietin (TPO) as the primary physiological regulator of megakaryopoiesis, a number of therapeutics have been developed\\u000a for thrombocytopenia and been tested in preclinical models and human

  9. Como Solicitar Los Beneficios del Seguro del Desempleo Transcripcin

    E-print Network

    Como Solicitar Los Beneficios del Seguro del Desempleo Transcripcin Bienvenido a uno de los de desempleo en California, usted ha venido al lugar correcto, y aqu estamos para servirle. Este es a recibir sus beneficios del desempleo. Cuando usted hace una llamada u oprime su botn en su computadora

  10. LA GESTIN DE LOS EVENTOS COMO UN PRODUCTO TURSTICO

    Microsoft Academic Search

    Nancy Fernndez Gonzlez; Jorge Luis Borroto Martnez

    2011-01-01

    Los viajes que se producen en el mundo, son realizados por diferentes motivaciones, necesidades e intereses, variables que son de constantes investigaciones y evaluaciones por los actores que intervienen en el proceso del turismo internacional, para poder satisfacerlas, como es el caso de los eventos. Los eventistas viajan motivados por el evento y sus temticas y pagan por ello pero

  11. CNCER DE PRSTATA Y EJERCICIO FSICO

    Microsoft Academic Search

    Bernat-Carles Serd

    2006-01-01

    The American College of Sports Medicine recommends aerobic exercise combined with a complete muscular workout in a healthy psychosocial environment. This general pres- cription can be applied to cancer patients. This program offers a physical exercise guide of strength and endurance adapted to pros- tate cancer patients. The program considers the characteristics and contraindications of strength building exercise allowing for

  12. La tipologa en la vivienda como precedente sustentable

    Microsoft Academic Search

    Selenne Galeana Cruz

    1970-01-01

    El presente artculo intenta realizar una aportacin para el anlisis tipolgico de la\\u000avivienda, en particular a la vivienda social. Esta intencin se enmarca en el anlisis de las\\u000acaractersticas de la vivienda adecuada, que se inscribe como uno de los Objetivos del Milenio\\u000apropuesto por la ONU, cuya evaluacin y monitoreo ha sido responsabilidad del Programa UNHABITAT.\\u000aPara su

  13. Sensitivity of Hydrologic Partitioning to Snowpack Dynamics, Como Creek, CO

    NASA Astrophysics Data System (ADS)

    Barnhart, T. B.; Molotch, N. P.; Harpold, A. A.; Knowles, J. F.; Anderson, S. P.

    2014-12-01

    Snowmelt is the primary source of surface water in the western United States and many other regions on Earth. Climate warming is forecast to impact the amount of precipitation that falls as snow and forms the mountain snowpack. Climate change induced alterations to snowpack translate to changes in snowpack magnitude, the timing of snowmelt, and changes in snowmelt rate. We ask how these perturbations may impact how snowmelt is partitioned between evapotranspiration (ET) and runoff (R) at Como Creek, a snowmelt dominated catchment on the Colorado Front Range. Como Creek is a 4.5 km2 headwater catchment spanning 2900-3560 m and is part of the Niwot Ridge Long Term Ecological Research Station and the Boulder Creek Critical Zone Observatory. We use observations of snow water equivalent (SWE), ET, and precipitation (P) from Niwot Ridge, CO, and discharge from Como Creek to explore relationships between snowpack dynamics and snowmelt partitioning. Measurements of ET are collected adjacent to Como Creek at the Niwot Ridge Ameriflux site and are assumed representative of the hydrologic fluxes in Como Creek. Analyses from point data show that years with higher peak SWE/P ratios partition proportionally more snowmelt to ET (pValue: 0.045). For example, water year (WY) 2005 has a peak SWE/P ratio of 0.49 and a growing season ET normalized by WY precipitation (ET/P) ratio of 0.48 while WY 2008 has a peak SWE/P ratio of 0.83 and an ET/P ratio of 0.82. Observations also show that years that experience later peak SWE (DOY=142) partition proportionally less snowmelt into ET (ET/P=0.42) compared to years that experience earlier peak SWE (DOY=86) and partition proportionally more snowmelt to ET (ET/P=0.56). Further point analyses also suggest that more rapid snowmelt results in proportionally less snowmelt partitioned to ET and more partitioned to runoff. To explore the underlying processes responsible for these relationships at the catchment scale we use the Regional Hydro-Ecologic Simulation System (RHESSys) to model how snowmelt is partitioned between ET and R under observed conditions and under a variety of climate change induced snowmelt timing, magnitude, and rate scenarios.

  14. El teatro como reflexin colectiva: Conversacin con Sergio Corrieri

    E-print Network

    Luzuriaga, Gerardo

    1983-04-01

    gente del Escambray se nos queja. Uno de los aspectos ms interesantes, a mi modo de ver, de la experiencia del Teatro Escambray es que todo este proceso se ha ido haciendo sobre la marcha, ha ido surgiendo, como t decas hace poco, de la prctica... grandes rasgos, por supuesto. Por nuestra convivencia en la zona y por los multiples canales naturales que eso nos brinda, nosotros estamos actualizados de la problemtica. Aparte, con el tiempo, el Escambray ha ido perdiendo artistas particulares en el...

  15. Power Factor Compensation (PFC) Power Factor Compensation

    E-print Network

    Knobloch,Jürgen

    Power Factor Compensation (PFC) Power Factor Compensation The power factor (PF) is defined as the ratio between the active power and the apparent power of a system. If the current and voltage are periodic with period , and [ ), then the active power is defined by ( ) ( ) (their inner product

  16. Learning with matrix factorizations

    E-print Network

    Srebro, Nathan, 1974-

    2004-01-01

    Matrices that can be factored into a product of two simpler matrices can serve as a useful and often natural model in the analysis of tabulated or high-dimensional data. Models based on matrix factorization (Factor Analysis, ...

  17. Factor V deficiency

    MedlinePLUS

    ... in blood plasma. These proteins are called blood coagulation factors. Factor V deficiency is caused by a ... Ragni MV. Hemorrhagic disorders: coagulation factor deficiencies. ... 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 167.

  18. ANALISIS DE LA MADUREZ COMO CLASE PROFESIONAL DE LOS ESPECIALISTAS DE LOS SISTEMAS DE INFORMACION GEOGRAFICA

    E-print Network

    Gilbes, Fernando

    ANALISIS DE LA MADUREZ COMO CLASE PROFESIONAL DE LOS ESPECIALISTAS DE LOS SISTEMAS DE INFORMACION ramatos@pupr.edu Es interesante observar como los profesionales de los Sistemas de Informacin Geogrfica

  19. The fungal GATA factors

    Microsoft Academic Search

    Claudio Scazzocchio

    2000-01-01

    The DNA-binding domains of eucaryotic GATA factors comprise a four-cysteine Zn finger and an adjacent basic region. Fungal GATA factors regulate nitrogen metabolism, light induction, siderophore biosynthesis and mating-type switching. Hydrophobic interactions determine binding-site specificity. Interactions with other factors may determine promoter specificity. One GATA factor has recently been shown to determine a drastic chromatin rearrangement.

  20. Factor X deficiency

    MedlinePLUS

    Factor X (ten) deficiency is a disorder caused by too little of a protein called factor X in the blood. It leads to problems with ... more of these clotting factors are missing. Factor X deficiency is often caused by a defect in ...

  1. Factores Reproductivos Asociados al Riesgo de Cncer del Seno

    E-print Network

    Danforth, Bryan Nicholas

    funcionamiento normal del seno como al riesgo de cncer del seno. Se sabe que estar en edad avanzada al momento edad temprana es un factor protector. Mientras ms joven sea la mujer al momento de tener su primer hijo, menor es su riesgo de desarrollar cncer del seno ms tarde en la vida. El riesgo de

  2. Important Water Quality Factors

    NSDL National Science Digital Library

    This site provides basic information about factors commonly analyzed in water quality studies of drinking water, waste water and natural water. The factors are listed alphabetically with descriptions and explanations about what the results of measurements mean in environmental terms.

  3. Factoring Polynomials and Fibonacci.

    ERIC Educational Resources Information Center

    Schwartzman, Steven

    1986-01-01

    Discusses the factoring of polynomials and Fibonacci numbers, offering several challenges teachers can give students. For example, they can give students a polynomial containing large numbers and challenge them to factor it. (JN)

  4. Risk Factors for Scleroderma

    MedlinePLUS

    ... Home For Patients Risk Factors Risk Factors for Scleroderma The cause of scleroderma is still unknown. Scientists ... help find improved therapies and a cure for scleroderma! quick links What is scleroderma? Frequently Asked Questions ...

  5. Multilevel Mixture Factor Models

    ERIC Educational Resources Information Center

    Varriale, Roberta; Vermunt, Jeroen K.

    2012-01-01

    Factor analysis is a statistical method for describing the associations among sets of observed variables in terms of a small number of underlying continuous latent variables. Various authors have proposed multilevel extensions of the factor model for the analysis of data sets with a hierarchical structure. These Multilevel Factor Models (MFMs)

  6. Multiple factor analysis

    Microsoft Academic Search

    L. L. Thurstone

    1931-01-01

    The purpose of the paper is to describe a more generally applicable method of factor analysis which has no restrictions as regards group factors and which does not restrict the number of general factors that are operative in producing the intercorrelation. Applications of the method to different types of correlation problems are suggested.

  7. Mesonic form factors

    Microsoft Academic Search

    Frederic D. R. Bonnet; Robert G. Edwards; George T. Fleming; Randy Lewis; David G. Richards

    2004-01-01

    We have started a program to compute the electromagnetic form factors of mesons. We discuss the techniques used to compute the pion form factor and present preliminary results computed with domain wall valence fermions on MILC asqtad lattices, as well as Wilson fermions on quenched lattices. These methods can easily be extended to ? ? ?? transition form factors.

  8. Mesonic form factors

    Microsoft Academic Search

    Frederic D. R. Bonnet; Robert G. Edwards; George T. Fleming; Randy Lewis; David G. Richards

    2004-01-01

    We have started a program to compute the electromagnetic form factors of mesons. We discuss the techniques used to compute the pion form factor and present preliminary results computed with domain wall valence fermions on MILC asqtad lattices, as well as Wilson fermions on quenched lattices. These methods can easily be extended to varrho --> gammapi transition form factors. This

  9. Mesonic Form Factors

    Microsoft Academic Search

    Frederic D. R. Bonnet; Robert G. Edwards; George T. Fleming; Randal Lewis; David Richards

    2003-01-01

    We have started a program to compute the electromagnetic form factors of mesons. We discuss the techniques used to compute the pion form factor and present preliminary results computed with domain wall valence fermions on MILC asqtad lattices, as well as Wilson fermions on quenched lattices. These methods can easily be extended to rho-to-gamma-pi transition form factors.

  10. Aerostructural safety factor criteria

    NASA Technical Reports Server (NTRS)

    Verderaime, V.

    1992-01-01

    The present modification of the conventional safety factor method for aircraft structures evaluation involves the expression of deterministic safety factors in probabilistic tolerance limit ratios; these are found to involve a total of three factors that control the interference of applied and resistive stress distributions. The deterministic expression is extended so that it may furnish a 'relative ultimate safety' index that encompasses all three distribution factors. Operational reliability is developed on the basis of the applied and the yield stress distribution interferences. Industry standards are suggested to be derivable from factor selections that are based on the consequences of failure.

  11. Exploratory Bi-Factor Analysis

    ERIC Educational Resources Information Center

    Jennrich, Robert I.; Bentler, Peter M.

    2011-01-01

    Bi-factor analysis is a form of confirmatory factor analysis originally introduced by Holzinger. The bi-factor model has a general factor and a number of group factors. The purpose of this article is to introduce an exploratory form of bi-factor analysis. An advantage of using exploratory bi-factor analysis is that one need not provide a specific

  12. K.K. Gan Como05 1 The Ohio State University

    E-print Network

    Gan, K. K.

    consumption! Use IBM 0.25 m CMOS Use Truelight high-power oxide common cathode VCSEL array VDC: VCSEL Pixel Detector #12;K.K. Gan Como05 2 Outline Introduction Proton Irradiation Studies Production Status Summary #12;K.K. Gan Como05 3 ATLAS Pixel Detector Inner most tracking detector Pixel size: 50

  13. Sobre Como Varian las Firmas Manuscritas con el Tiempo: una Modelizacion Sigma Lognormal

    E-print Network

    Autonoma de Madrid, Universidad

    de edad basado en los par´ametros del modelo. 1 Introducci´on Como en cualquier nuevo ´area de- conocimiento, con el objetivo de conseguir menores tasas de error. Como conse- cuencia, se han pasado por alto nueva aproximaci´on para el estudio de firmas pertenecientes a grupos de edades dis- tintas. #12;La

  14. DE VIAJES Y MIEDOS: LA AGORAFOBIA COMO UNA FORMA DE CONTROL ECONMICO

    Microsoft Academic Search

    Maximiliano Korstanje

    2008-01-01

    El objetivo del siguiente trabajo es describir casos anlogos de fobia o miedo a los viajes en otras culturas y tiempos diferente a los modernos. En este sentido, consideramos que tanto la cultura aymar como la vida en la antigua roma nos proveen de ejemplos suficientes para considerar a la fobia a los viajes como un problema en extensin. Por

  15. Anlisis econmico de la bio-carbonizacin como prctica de manejo agrcola

    Microsoft Academic Search

    Juan Andrs Ramrez; Ramn Rosales

    2009-01-01

    Las altas concentraciones de gases de efecto invernadero, especficamente CO2, han sido sealadas como la principal causa del cambio climtico. La adopcin de prcticas agrcolas capaces de incrementar el contenido de carbono en el suelo, ha sido propuesta como una estrategia de bajo costo y disponibilidad inmediata para enfrentar este fenmeno. La Bio-carbonizacin es una de estas prcticas agrcolas, la

  16. Form factors: Experimental Progress

    NASA Astrophysics Data System (ADS)

    Jones, Mark

    2004-10-01

    A review of experiments which measured nucleon electromagnetic form factors since the early 1990's will be presented. Before 1990, the form factors were predominantly extracted from elastic electron-proton and electron-deuteron cross section measurements. The lack of a free neutron target made measurement of the neutron form factors much more difficult than the proton form factors. New facilities and experimental techniques were needed to make precision measurement of the neutron form factor and extend precision measurement of the proton electric form factor to four-momentum transfer squared, Q^2, greater than 1 GeV^2. New accelerator facilities, such as Mainz Microtron and Jefferson Lab Continuous Electron Beam Accelerator, have produced high current and high duty factor electron beams with large polarizations. The high-duty factor beam made precision coincidence experiments feasible for quasi-free scattering on deuteron. Using the polarized electron beam, experiments measured the recoil polarization of the outgoing nucleon in elastic electron-proton scattering and quasi-free electron-deuteron scattering and were able to extract the electric form factor. Advances in polarized deuteron and helium targets have facilitated beam-target asymmetry measurements from which neutron form factors can be extracted. Theoretical advances have enabled understanding of knockout of the neutron in electron-deuteron scattering and quasi-free electron-^3He scattering. Using these calculations, kinematics are selected which maximize the sensitivity to neutron form factor while minimizing the effects of the reaction mechanism which are calculable in the theory. All these advances have combined to improve the precision and expand the Q^2 range of our knowledge of nucleon electromagnetic form factors. The data provides a strong baseline for testing theoretical models of the nucleon structure.

  17. Meson electromagnetic form factors

    E-print Network

    Stanislav Dubnicka; Anna Z. Dubnickova

    2012-10-23

    The electromagnetic structure of the pseudoscalar meson nonet is completely described by the sophisticated Unitary&Analytic model, respecting all known theoretical properties of the corresponding form factors.

  18. Factor IX assay

    MedlinePLUS

    ... one of the substances involved in blood clotting (coagulation). ... deficiency of factor IX (hemophilia B) Disseminated intravascular coagulation ( DIC ) Fat malabsorption Liver disease (such as cirrhosis ) ...

  19. Factor VII assay

    MedlinePLUS

    ... one of the substances involved in blood clotting (coagulation). ... to: Congenital deficiency of factor VII Disseminated intravascular coagulation ( DIC ) Fat malabsorption Liver disease (such as cirrhosis ) ...

  20. Analytic Couple Modeling Introducing Device Design Factor, Fin Factor, Thermal Diffusivity Factor, and Inductance Factor

    NASA Technical Reports Server (NTRS)

    Mackey, Jon; Sehirlioglu, Alp; Dynys, Fred

    2014-01-01

    A set of convenient thermoelectric device solutions have been derived in order to capture a number of factors which are previously only resolved with numerical techniques. The concise conversion efficiency equations derived from governing equations provide intuitive and straight-forward design guidelines. These guidelines allow for better device design without requiring detailed numerical modeling. The analytical modeling accounts for factors such as i) variable temperature boundary conditions, ii) lateral heat transfer, iii) temperature variable material properties, and iv) transient operation. New dimensionless parameters, similar to the figure of merit, are introduced including the device design factor, fin factor, thermal diffusivity factor, and inductance factor. These new device factors allow for the straight-forward description of phenomenon generally only captured with numerical work otherwise. As an example a device design factor of 0.38, which accounts for thermal resistance of the hot and cold shoes, can be used to calculate a conversion efficiency of 2.28 while the ideal conversion efficiency based on figure of merit alone would be 6.15. Likewise an ideal couple with efficiency of 6.15 will be reduced to 5.33 when lateral heat is accounted for with a fin factor of 1.0.

  1. SOCIOLOGICAL METHODS & RESEARCHRaftery / BAYES FACTORS Bayes Factors and BIC

    E-print Network

    Raftery, Adrian

    SOCIOLOGICAL METHODS & RESEARCHRaftery / BAYES FACTORS Bayes Factors and BIC Comment on "A Critique for Bayes factors. I thank Weakliem for bringingthissubtlebutimportanttopictotheattentionofsociologists. In 1986, I proposed replacing P values by Bayes factors as the basis for hypothesis testing and model

  2. Dinmica del sistema agroforestal de chagras como eje de la produccin indgena en el Trapecio Amaznico (Colombia) Chagras' agroforestal system dynamics as the basis for indigenous production in the Amazonian Trapezium (Colombia)

    Microsoft Academic Search

    Luz Amparo Triana-Moreno; Nohra Cecilia Rodrguez; Jess Garca

    Resumen: La tradicin indgena, la pertenencia a la cuenca Amaznica y la cercana a un importante centro urbano como Leticia (Amazonas, Colombia) son factores que aportan elementos caractersticos al sistema de produccin de Ciudad Jitoma y lo dife- rencian de otras formas de produccin indgena y no-indgena, incluso dentro de la misma regin ama- znica. En el presente estudio se

  3. Exogenous Factors and Psoriasis

    Microsoft Academic Search

    E. Dika; H. I. Maibach

    2004-01-01

    Psoriasis is a chronic relapsing disease characterized by variable clinical features. Several factors may exacerbate its manifestations, or even trigger the disease, such as traumatic injury to the skin, physical and psychological stress, cold weather, excessive alcohol intake, and drugs such as lithium and beta-blockers. We describe the most common features of psoriasis and the exogenous factors that may induce,

  4. Square form factorization

    NASA Astrophysics Data System (ADS)

    Gower, Jason E.; Wagstaff, Samuel S., Jr.

    2008-03-01

    We present a detailed analysis of SQUFOF, Daniel Shanks' Square Form Factorization algorithm. We give the average time and space requirements for SQUFOF. We analyze the effect of multipliers, either used for a single factorization or when racing the algorithm in parallel.

  5. Vitiligo Exogenous Factors

    Microsoft Academic Search

    Hagit Matz; Ethel Tur

    2004-01-01

    Vitiligo is an acquired depigmentary disorder of the skin that results from the selective destruction of melanocytes. The etiology of vitiligo is poorly understood. There appears to be a genetic predisposition, but additional factors are probably involved. The purpose of this article is to outline the factors that might play a role in the development of vitiligo. These include trauma

  6. Recombinant growth factors

    Microsoft Academic Search

    Lawrence T. Goodnough; Kenneth C. Anderson

    1995-01-01

    Recombinant human growth factors are expected to have a significant impact on the use of allogeneic blood components. For example, subsequent to the approval of recombinant human erythropoietin, blood transfusions in renal dialysis patients declined substantially.1 Likewise, myeloid growth factors have reduced infections and hospital stay by promoting hematologic recovery after high dose ablative chemotherapy. The high costs of these

  7. Learning with Matrix Factorizations

    E-print Network

    Srebro, Nathan

    Learning with Matrix Factorizations Nati Srebro Department of Electrical Engineering and Computer Reduction yy u V' YY datadata U titles users titles ? #12;Matrix Factorization V' YY datadata U X rank k ­ Clustering as an extreme (when rows of U sparse) · Unconstrained: Low Rank Approximation #12;Matrix

  8. Overview of environmental factors

    NASA Technical Reports Server (NTRS)

    Purvis, C. K.

    1989-01-01

    The orbital environment is complex, dynamic, and comprised of both natural and system-induced components. Several environment factors are important for materials. Materials selection/suitability determination requires consideration of each and all factors, including synergisms among them. Understanding and evaluating these effects will require ground testing, modeling, and focused flight experimentation.

  9. EFFECTS OF H2S ADDITION ON THE PERFORMANCE OF FRESH VS. USED CoMo CATALYSTS

    Microsoft Academic Search

    Lillian A. Rartkel

    1991-01-01

    When a Co\\/Mo catalyst is used for processing vanadium-containing heavy oils, vanadium deposits on the catalyst. As the amount of vanadium on the CoMo catalyst increases, the catalytic effects of CoMo decline and the presence of vanadium starts to influence the hydroprocessing products. Model feeds have been used to explore the changes in the catalytic activity of CoMo, aged CoMo,

  10. Block LU factorization

    NASA Technical Reports Server (NTRS)

    Demmel, James W.; Higham, Nicholas J.; Schreiber, Robert S.

    1992-01-01

    Many of the currently popular 'block algorithms' are scalar algorithms in which the operations have been grouped and reordered into matrix operations. One genuine block algorithm in practical use is block LU factorization, and this has recently been shown by Demmel and Higham to be unstable in general. It is shown here that block LU factorization is stable if A is block diagonally dominant by columns. Moreover, for a general matrix the level of instability in block LU factorization can be founded in terms of the condition number kappa(A) and the growth factor for Gaussian elimination without pivoting. A consequence is that block LU factorization is stable for a matrix A that is symmetric positive definite or point diagonally dominant by rows or columns as long as A is well-conditioned.

  11. Growth factors in haemopoiesis.

    PubMed

    Jones, A L; Millar, J L

    1989-01-01

    Haemopoietic growth factors have for over two decades allowed experimentalists to grow haemopoietic bone marrow cells in vitro. With refinements in technique and the discovery of novel growth factors, all of the known haemopoietic lineages can now be grown in vitro. This has allowed a much greater understanding of the complex process of haemopoiesis from the haemopoietic stem cell to the mature, functioning end-cell. The in vivo action of these growth factors has been harder to investigate. Although recombinant technology has afforded us the much greater quantities necessary for in vivo work, problems remain with administration because of effects on other tissues. Interpretation of results is difficult because of the complex inter-relationships which exist between factors. Some of these have been defined in vitro and it appears likely that they also operate in vivo. Erythropoietin is a physiological regulator of erythropoiesis. It has been detected in vivo with levels responding appropriately to stress (i.e. elevated in anaemia) and, when administered in pharmacological doses, has been shown to correct anaemia. Granulocyte/macrophage colony-stimulating factor (GM-CSF) has been detected in vivo and may influence the production and function of granulocytes and macrophages, although how it is regulated is unknown. Granulocyte colony-stimulating factor (G-CSF) and macrophage colony-stimulating factor are ore lineage-specific. Interleukin 3 (IL-3), although it has not been detected in vivo, may act on a primitive marrow precursor by expanding the population and making these cells more susceptible to other growth factors, such as GM-CSF. Interleukin 1 (IL-1) has been detected in vivo, does not appear to have any isolated action on bone marrow (except possibly radioprotection) but probably acts synergistically with other growth factors, such as G-CSF. Interleukins 2, 4, 5 and 6 have not been detected in vivo. All have effects on B-cells. In addition IL-2 is an essential factor for the in vitro growth of T-cells and may have antitumour effects in vivo. IL-5 is an eosinophil growth factor in vitro. Megakaryocytopoiesis is also affected by humoral factors. Factors, alone or in combination, may be useful to restore functional granulopoiesis when used therapeutically. Some can be used as anticancer agents, although there may be a risk of induction of haematological malignancy. Increased understanding of their physiological roles will allow a more rational use. PMID:2645965

  12. Journal Information Journal Impact Factor

    E-print Network

    Krejc, Pavel

    Journal Information Journal Impact Factor 5-Year Journal Impact Factor Journal Self Cites Journal Cites Impact Factor 5-Year Impact Factor Immediacy Index Citable Items Cited Half- life Citing Half Used in Impact Factor Calculation 12 Impact Factor 0.222 Self Cites 16 (6% of 240) Self Cites to Years

  13. Journal Information Journal Impact Factor

    E-print Network

    Krejc, Pavel

    Journal Information Journal Impact Factor 5-Year Journal Impact Factor Journal Self Cites Journal Mark Journal Title ISSN Total Cites Impact Factor 5-Year Impact Factor Immediacy Index Citable Items Used in Impact Factor Calculation 51 Impact Factor 0.300 Self Cites 39 (4% of 834) Self Cites to Years

  14. Factors augmenting allergic reactions.

    PubMed

    Niggemann, B; Beyer, K

    2014-12-01

    Elicitors of anaphylactic reactions are any sources of protein with allergenic capacity. However, not all allergic reactions end up in the most severe form of anaphylaxis. Augmenting factors may explain why certain conditions lead to anaphylaxis. Augmenting factors may exhibit three effects: lowering the threshold, increasing the severity, and reversing acquired clinical tolerance. Common augmenting factors are physical exercise, menstruation, NSAIDs, alcohol, body temperature, acute infections, and antacids. Therapeutic options may address causative, preventive, pragmatic, or symptomatic considerations: avoid the eliciting food, take an antihistamine before any situation with a possible risk of augmentation, separate food and sport (at least for 2h), and carry an adrenaline autoinjector at all times. Individual patterns include summation effects and specific patterns. In conclusion, in the case of a suggestive history but a negative oral challenge, one should consider the possible involvement of augmenting factors; after anaphylactic reactions, always ask for possible augmentation and other risk factors during the recent past; if augmentation is suspected, oral food challenges should be performed in combination with augmenting factors; and in the future, standardized challenge protocols including augmenting factors should be established. PMID:25306896

  15. Physics of Factorization

    E-print Network

    M. Revzen; A. Mann; J. Zak

    2005-03-30

    The N distinct prime numbers that make up a composite number M allow $2^{N-1}$ bi partioning into two relatively prime factors. Each such pair defines a pair of conjugate representations. These pairs of conjugate representations, each of which spans the M dimensional space are the familiar complete sets of Zak transforms (J. Zak, Phys. Rev. Let.{\\bf 19}, 1385 (1967)) which are the most natural representations for periodic systems. Here we show their relevance to factorizations. An example is provided for the manifestation of the factorization.

  16. The Quark Impact Factors

    E-print Network

    V. S. Fadin; R. Fiore; M. I. Kotsky; A. Papa

    1999-08-05

    We calculate in the next-to-leading approximation the non-forward quark impact factors for both singlet and octet color representation in the $t$-channel. The integral representation of the octet impact factor in the general case of arbitrary space-time dimension and massive quark flavors is used to check the so-called "second bootstrap condition" for the gluon Reggeization at the next-to-leading logarithmic approximation in perturbative QCD. We find that it is satisfied for both helicity conserving and non-conserving parts. The integrations are then performed for the explicit calculation of the impact factors in the massless quark case.

  17. Factorizations in finite groups

    SciTech Connect

    Kulikov, Viktor S [Steklov Mathematical Institute, Russian Academy of Sciences, Moscow (Russian Federation)] [Steklov Mathematical Institute, Russian Academy of Sciences, Moscow (Russian Federation)

    2013-02-28

    A necessary condition for uniqueness of factorizations of elements of a finite group G with factors belonging to a union of some conjugacy classes of G is given. This condition is sufficient if the number of factors belonging to each conjugacy class is big enough. The result is applied to the problem on the number of irreducible components of the Hurwitz space of degree d marked coverings of P{sup 1} with given Galois group G and fixed collection of local monodromies. Bibliography: 9 titles.

  18. Brain Tumor Risk Factors

    MedlinePLUS

    ... Financials Board of Directors Scientific Advisory Council & Reviewers Leadership News Careers Brain Tumor Information Brain Anatomy Brain Tumor Symptoms Diagnosis Types of Tumors Tumor Grade Risk Factors Brain Tumor ...

  19. New microbial growth factor.

    PubMed Central

    Bok, S H; Casida, L E

    1977-01-01

    A screening procedure was used to isolate from soil a Penicillium sp., two bacterial isolates, and a Streptomyces sp. that produced a new microbial growth factor. This factor was an absolute growth requirement for three soil bacteria. The Penicillium sp. and one of the bacteria requiring the factor, an Arthrobacter sp., were selected for more extensive study concerning the production and characteristics of the growth factor. It did not seem to be related to the siderochromes. It was not present in soil extract, rumen fluid, or any other medium component tested. It appears to be a glycoprotein of high molecular weight, and it has high specific activity. When added to the diets for a meadow vole mammalian test system, it caused an increased consumption of diet without a concurrent increase in rate of weight gain. PMID:327929

  20. Screening and Risk Factors

    Cancer.gov

    Close Window State Cancer Profiles Quick Reference Guides ? Quick Reference Guides Index Screening and Risk Factors Send to Printer Text description of this image. Site Home Policies Accessibility Viewing Files FOIA Contact Us U.S. Department of Health

  1. Aerospace Human Factors

    NASA Technical Reports Server (NTRS)

    Jordan, Kevin

    1999-01-01

    The following contains the final report on the activities related to the Cooperative Agreement between the human factors research group at NASA Ames Research Center and the Psychology Department at San Jose State University. The participating NASA Ames division has been, as the organization has changed, the Aerospace Human Factors Research Division (ASHFRD and Code FL), the Flight Management and Human Factors Research Division (Code AF), and the Human Factors Research and Technology Division (Code IH). The inclusive dates for the report are November 1, 1984 to January 31, 1999. Throughout the years, approximately 170 persons worked on the cooperative agreements in one capacity or another. The Cooperative Agreement provided for research personnel to collaborate with senior scientists in ongoing NASA ARC research. Finally, many post-MA/MS and post-doctoral personnel contributed to the projects. It is worth noting that 10 former cooperative agreement personnel were hired into civil service positions directly from the agreements.

  2. Coagulation Factors Test

    MedlinePLUS

    ... of this website will be limited. Search Help? Coagulation Factors Share this page: Was this page helpful? ... if a person has a sufficient amount of coagulation activity in order to control the blood clotting ...

  3. Factor XII assay

    MedlinePLUS

    ... one of the substances involved in blood clotting (coagulation). ... Gailani D, Neff AT. Rare coagulation factor deficiencies. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, eds. Hematology: Basic Principles and Practice . 6th ...

  4. von Willebrand Factor Test

    MedlinePLUS

    ... Platelet Count , Platelet Function Tests , Complete Blood Count , Coagulation Factor VIII , PT , PTT At a Glance Test ... a protein , one of several components of the coagulation system that work together to stop bleeding and ...

  5. Power Factor Improvement

    E-print Network

    Viljoen, T. A.

    1979-01-01

    and disadvantages of various locations in the electrical network are described including the cost of installation and network capacity improvement. Sizing of capacitors is also covered. Finally, some case studies involving power factor improvement are presented...

  6. Teleoperator human factors study

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The progress made on the Teleoperator Human Factors Study program is summarized. Technical and programmatic problems that were encountered were discussed along with planned activities. The report contains four sections: Work Performed, Future Work, Problems Encountered, and Cost Information

  7. Teleoperator human factors study

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The progress made on the Teleoperator Human Factors Study program is summarized. Technical and programmatic problems that were encountered are discussed along with planned activity. Work performed, future work, problems encountered, and cost information comprise the topics addressed herein.

  8. AFINALES DE 1974, despus de una desas-trosa combinacin de enfermedades como el

    E-print Network

    Nacional Autnoma de Mxico, Universidad

    alimento y refu- gio del hurn. En 1988, el descubrimiento de las colonias ms extensas de perros llaneros(Cynomys ludovicianus) en Norteamrica en la regin de Janos- Casas Grandes,nos llev a proponer este sitio como un rea

  9. Keratinocyte growth factor

    Microsoft Academic Search

    Jeffrey S. Rubin; Donald P. Bottaro; Marcio Chedid; Toru Miki; Dina Ron; Hyae-Gyeong Cheon; William G. Taylor; Emma Fortney; Hiromi Sakata; Paul W. Finch; William J. LaRochelle

    1995-01-01

    Keratinocyte growth factor (KGF) is a member of the heparin-binding fibroblast growth factor family (FGF-7) with a distinctive pattern of target-cell specificity. Studies performed in cell culture suggested that KGF was mitogenically active only on epithelial cells, albeit from a variety of tissues. In contrast, KGF was produced solely by cells of mesenchymal origin, leading to the hypothesis that it

  10. Optimizing Power Factor Correction

    E-print Network

    Phillips, R. K.; Burmeister, L. C.

    OPTIMIZING POWER FACTOR CORRECTION Robert K. Phillips and Louis C. Burmeister, Mechanical Engineering, University of Kansas, Lawrence, KS The optimal investment for power factor correcting capacitors for Kansas Power and Light Company large... that varles from utility to utility and even between different rate schedules of the same utility. Two examples show the difference between utilities. The Kansas City Power and Light Company "General Service Large" Rate Schedule l-GL provides no penalty...

  11. The Gluon Impact Factors

    E-print Network

    V. S. Fadin; R. Fiore; M. I. Kotsky; A. Papa

    1999-08-05

    We calculate in the next-to-leading approximation the non-forward gluon impact factors for arbitrary color state in the $t$-channel. In the case of the octet state we check the so-called "second bootstrap condition" for the gluon Reggeization in QCD, using the integral representation for the impact factors. The condition is fulfilled in the general case of an arbitrary space-time dimension and massive quark flavors for both helicity conserving and non-conserving parts.

  12. [Aggravating factors of rosacea].

    PubMed

    Jaworek, Andrzej Kazimierz; Wojas-Pelc, Anna; Pastuszczak, Maciej

    2008-01-01

    Rosacea is a chronic, inflammatory skin disease which is mainly localized in the central region of the face. Papules and pustules appear on the erythematic ground. Rosacea is common in population. Four subtypes of rosacea (erythematoteleangiectatic rosacea, ETR; papulo - pustular rosacea, PPR; ocular rosacea and phymatous rosacea) are classified (according to current classification) and one variant rosacea (granulomatous rosacea, GR). It is considered that an attempt to determine of triggering factors of rosacea should be the first step to treatment. Then it should be tried to eliminate contact with them. The aim of this study was an analysis of triggering factors of rosacea. 43 women and 26 men treated in the Dermatology Outpatient's Clinic of Jagiellonian University School of Medicine in Cracow were enrolled in the study. All patients were asked which factors trigger skin changes according to them. Patients mentioned most often: stress (58 percent), sun exposure (56.5 per. cent), alcohol (33.3 percent), exercise (29 percent), drinking coffee (21.7 percent) and hot meals (20.3 percent). They regarded the sun as the most strongly aggravating factor of rosacea (29.2 percent). It seems, that elimination and reduction of contact with aggravating factors is still an undervalued aspect of rosacea's treatment. Patients' motivation for use of prevention seems to be also very important. Knowledge about aggravating factors of rosacea, coming directly from patients' observations, may help in more effective treatment. PMID:18724544

  13. Factor Loading Estimation Error and Stability Using Exploratory Factor Analysis

    ERIC Educational Resources Information Center

    Sass, Daniel A.

    2010-01-01

    Exploratory factor analysis (EFA) is commonly employed to evaluate the factor structure of measures with dichotomously scored items. Generally, only the estimated factor loadings are provided with no reference to significance tests, confidence intervals, and/or estimated factor loading standard errors. This simulation study assessed factor loading

  14. Diet and hemostatic factors.

    PubMed

    Tracy, R P

    1999-11-01

    The coagulation, fibrinolytic, and platelet activating systems are complex and interact extensively, and with other systems such as inflammation. Key reactions often require biomembranes, suggesting that dietary lipids, to the extent that they influence membrane composition, may have important regulatory roles. Also, recent evidence suggests that both postprandial and fasting lipoproteins may be associated with either factor levels or activation state or both. This issue has added importance because several hemostatic and fibrinolytic factors are known CVD risk factors. Although there are associations between fasting lipid levels and several coagulation and fibrinolytic factors, the mechanisms are unclear, as are the implications for intervention. In general, postprandial lipids are at least somewhat procoagulant because they activate factor VII. It remains to be demonstrated, however, that this postprandial activation has important clinical correlates. Dietary supplementation with marine omega-3 fatty acids does prolong the bleeding time and may decrease thrombotic potential; however, other than this, little is known about the direct effects of dietary fatty acids on hemostatic and fibrinolytic activities. Much work is needed in carefully controlled studies to expand our knowledge in this important area. PMID:11122717

  15. DSN human factors project

    NASA Technical Reports Server (NTRS)

    Chafin, R. L.; Martin, T. H.

    1980-01-01

    The project plan was to hold focus groups to identify the factors influencing the ease of use characteristics of software and to bond the problem. A questionnaire survey was conducted to evaluate those factors which were more appropriately measured with that method. The performance oriented factors were analyzed and relationships hypothesized. The hypotheses were put to test in the experimental phase of the project. In summary, the initial analysis indicates that there is an initial performance effect favoring computer controlled dialogue but the advantage fades fast as operators become experienced. The user documentation style is seen to have a significant effect on performance. The menu and prompt command formats are preferred by inexperienced operators. The short form mnemonic is least favored. There is no clear best command format but the short form mnemonic is clearly the worst.

  16. Psychological Factors in Asthma

    PubMed Central

    2008-01-01

    Asthma has long been considered a condition in which psychological factors have a role. As in many illnesses, psychological variables may affect outcome in asthma via their effects on treatment adherence and symptom reporting. Emerging evidence suggests that the relation between asthma and psychological factors may be more complex than that, however. Central cognitive processes may influence not only the interpretation of asthma symptoms but also the manifestation of measurable changes in immune and physiologic markers of asthma. Furthermore, asthma and major depressive disorder share several risk factors and have similar patterns of dysregulation in key biologic systems, including the neuroendocrine stress response, cytokines, and neuropeptides. Despite the evidence that depression is common in people with asthma and exerts a negative impact on outcome, few treatment studies have examined whether improving symptoms of depression do, in fact, result in better control of asthma symptoms or improved quality of life in patients with asthma. PMID:20525122

  17. Factorizations and Physical Representations

    E-print Network

    M. Revzen; F. C. Khanna; A. Mann; J. Zak

    2005-08-25

    A Hilbert space in M dimensions is shown explicitly to accommodate representations that reflect the prime numbers decomposition of M. Representations that exhibit the factorization of M into two relatively prime numbers: the kq representation (J. Zak, Phys. Today, {\\bf 23} (2), 51 (1970)), and related representations termed $q_{1}q_{2}$ representations (together with their conjugates) are analysed, as well as a representation that exhibits the complete factorization of M. In this latter representation each quantum number varies in a subspace that is associated with one of the prime numbers that make up M.

  18. The transcription factor encyclopedia.

    PubMed

    Yusuf, Dimas; Butland, Stefanie L; Swanson, Magdalena I; Bolotin, Eugene; Ticoll, Amy; Cheung, Warren A; Zhang, Xiao Yu Cindy; Dickman, Christopher T D; Fulton, Debra L; Lim, Jonathan S; Schnabl, Jake M; Ramos, Oscar H P; Vasseur-Cognet, Mireille; de Leeuw, Charles N; Simpson, Elizabeth M; Ryffel, Gerhart U; Lam, Eric W-F; Kist, Ralf; Wilson, Miranda S C; Marco-Ferreres, Raquel; Brosens, Jan J; Beccari, Leonardo L; Bovolenta, Paola; Benayoun, Brnice A; Monteiro, Lara J; Schwenen, Helma D C; Grontved, Lars; Wederell, Elizabeth; Mandrup, Susanne; Veitia, Reiner A; Chakravarthy, Harini; Hoodless, Pamela A; Mancarelli, M Michela; Torbett, Bruce E; Banham, Alison H; Reddy, Sekhar P; Cullum, Rebecca L; Liedtke, Michaela; Tschan, Mario P; Vaz, Michelle; Rizzino, Angie; Zannini, Mariastella; Frietze, Seth; Farnham, Peggy J; Eijkelenboom, Astrid; Brown, Philip J; Laperrire, David; Leprince, Dominique; de Cristofaro, Tiziana; Prince, Kelly L; Putker, Marrit; del Peso, Luis; Camenisch, Gieri; Wenger, Roland H; Mikula, Michal; Rozendaal, Marieke; Mader, Sylvie; Ostrowski, Jerzy; Rhodes, Simon J; Van Rechem, Capucine; Boulay, Gaylor; Olechnowicz, Sam W Z; Breslin, Mary B; Lan, Michael S; Nanan, Kyster K; Wegner, Michael; Hou, Juan; Mullen, Rachel D; Colvin, Stephanie C; Noy, Peter John; Webb, Carol F; Witek, Matthew E; Ferrell, Scott; Daniel, Juliet M; Park, Jason; Waldman, Scott A; Peet, Daniel J; Taggart, Michael; Jayaraman, Padma-Sheela; Karrich, Julien J; Blom, Bianca; Vesuna, Farhad; O'Geen, Henriette; Sun, Yunfu; Gronostajski, Richard M; Woodcroft, Mark W; Hough, Margaret R; Chen, Edwin; Europe-Finner, G Nicholas; Karolczak-Bayatti, Magdalena; Bailey, Jarrod; Hankinson, Oliver; Raman, Venu; LeBrun, David P; Biswal, Shyam; Harvey, Christopher J; DeBruyne, Jason P; Hogenesch, John B; Hevner, Robert F; Hligon, Christophe; Luo, Xin M; Blank, Marissa Cathleen; Millen, Kathleen Joyce; Sharlin, David S; Forrest, Douglas; Dahlman-Wright, Karin; Zhao, Chunyan; Mishima, Yuriko; Sinha, Satrajit; Chakrabarti, Rumela; Portales-Casamar, Elodie; Sladek, Frances M; Bradley, Philip H; Wasserman, Wyeth W

    2012-01-01

    Here we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration. Our consortium of over 100 researchers has collectively contributed over 130 mini review articles on pertinent human, mouse and rat TFs. Notable features of the TFe website include a high-quality PDF generator and web API for programmatic data retrieval. TFe aims to rapidly educate scientists about the TFs they encounter through the delivery of succinct summaries written and vetted by experts in the field. TFe is available at http://www.cisreg.ca/tfe. PMID:22458515

  19. Chromatin elongation factors.

    PubMed

    Svejstrup, Jesper Q

    2002-04-01

    As RNA polymerase II leaves a gene promoter to transcribe the coding region, it faces a major obstacle - nucleosomes tightly wrapped into chromatin. Mechanisms to deal with this obstacle clearly exist in cells, as transcription through chromatin is very efficient in vivo, whereas nucleosomal templates pose a considerable problem for polymerase progression in reconstituted in vitro systems. Advances in our understanding of transcriptional elongation through chromatin have been made possible recently by the identification of several accessory factors that assist polymerase in the process. Insights into the function of these factors have been gained by a combination of yeast genetics and biochemical studies in mammalian systems. PMID:11893488

  20. The Structure of Factor Oracles

    Microsoft Academic Search

    Maxime Crochemore; Lucian Ilie; Emine Seid-hilmi

    2007-01-01

    The factor oracle is a relatively new data structure for the set of factors of a string. It has been introduced by Allauzen, Crochemore, and Raffinot in 1999. It may recognize non- factors (hence the name \\

  1. LA AUDITORA COMO UNA DISCIPLINA DENTRO DE LAS CIENCIAS CONTABLES. ENFOQUES TERICOS Y METODOLGICOS DE SU PRAXIS

    Microsoft Academic Search

    Niurdis Cudeiro Rodrguez; Ninel Rafael Daz Martnez; Yudy Aguila Cudeiro

    2012-01-01

    La Contabilidad, como Ciencia Social, presenta entre sus disciplinas la Auditora, la cual se manifiesta como praxis de sus principios tericos y metodolgicos. La Auditora tiene entre sus premisas la obtencin y evaluacin de evidencias que presenten la realidad econmica de las empresas, validando su capacidad para la realizacin de los procesos mercantiles tanto interno como externo. La gnesis del

  2. Factors Affecting Photosynthesis!

    E-print Network

    Kudela, Raphael M.

    Factors Affecting Photosynthesis! Temperature Eppley (1972) Light Sverdrup's Critical Depth-493, but the general concept is still valid! ! #12;PB opt & Temperature! #12;Photosynthesis & Temperature! Remember: in the laboratory, we can measure photosynthesis versus irradiance (PvsE) and calculate Ek, Pmax, and alpha

  3. The Three Faith Factors.

    ERIC Educational Resources Information Center

    DiIulio, John J., Jr.

    2002-01-01

    Discusses whether religion can affect health and social welfare and what types of religious influences are most beneficial to the individual and society, identifying three separate but related faith factors: organic religion, programmatic religion, and ecological religion. Examines research on faith-based approaches to social and urban problems.

  4. Robust Bayesian Factor Analysis

    ERIC Educational Resources Information Center

    Hayashi, Kentaro; Yuan, Ke-Hai

    2003-01-01

    Bayesian factor analysis (BFA) assumes the normal distribution of the current sample conditional on the parameters. Practical data in social and behavioral sciences typically have significant skewness and kurtosis. If the normality assumption is not attainable, the posterior analysis will be inaccurate, although the BFA depends less on the current

  5. Scale Factor X

    NSDL National Science Digital Library

    2010-01-01

    In this game, students navigate a maze to get to a math challenge. The three challenges are: move blue and green "fuel cells" around to match the ratios in the given containers; measure shapes to determine the scale factors needed to make them match the given templates; determine how to place bases on a map based on clues involving proportions.

  6. A Formula for Factoring.

    ERIC Educational Resources Information Center

    Roebuck, Kay I. Meeks

    1997-01-01

    Suggests use of the quadratic formula to build understanding that connections between factors and solutions to equations work both ways. Making use of natural connections among concepts allows students to work more efficiently. Presents four sample problems showing the roots of equations. Messy quadratic equations with rational roots can be solved

  7. Optimal power factor correction

    SciTech Connect

    Mostafa, M. (Electrical and Computer Engineering Dept., College of Engineering and Petroleum, Kuwait Univ. (KW))

    1988-08-01

    This paper discusses the different parameters affecting the economic feasibility of power factor correction. It will be shown that the specific costs of the transmission and compensation elements as well as those of the electric energy and power losses have a decisive influence on the achievable overall saving. After formulating an objective function representing this overall saving, taking also the load factor into account an analytical approach to the determination of the optimal size of the compensation equipment is presented. A generalized chart is given which enables the designer to know whether the power factor correction is feasible or not under any circumstances. Also, the most suitable degree of reactive power compensation can be directly found. The results obtained from a digital program are also given to indicate the sensitivity of the optimal compensation factor to changes in system parameters such as the specific energy loss cost and the annual rate of interest and depreciation. Moreover, the good agreement of the results of the digital computation with those determined using the suggested simple generalized chart, could be realized.

  8. Prime type III factors

    PubMed Central

    Shlyakhtenko, Dimitri

    2000-01-01

    It is shown that for each 0 < ? < 1, the free ArakiWoods factor of type III? cannot be written as a tensor product of two diffuse von Neumann algebras (i.e., is prime) and does not contain a Cartan subalgebra. PMID:11058159

  9. Probabilistic Matrix Factorization

    Microsoft Academic Search

    Ruslan Salakhutdinov; Andriy Mnih

    2007-01-01

    Many existing approaches to collaborative filtering can nei ther handle very large datasets nor easily deal with users who have very few ratings. In this paper we present the Probabilistic Matrix Factorization (PMF) model which scales linearly with the number of observations and, more importantly, performs well on the large, sparse, and very imbalanced Netflix dataset. We furth er extend

  10. Introduction to human factors

    SciTech Connect

    Winters, J.M.

    1988-03-01

    Some background is given on the field of human factors. The nature of problems with current human/computer interfaces is discussed, some costs are identified, ideal attributes of graceful system interfaces are outlined, and some reasons are indicated why it's not easy to fix the problems. (LEW)

  11. El espacio dramtico como signo: La noche de los asesinos de Jos Triana

    E-print Network

    Melé ndez, Priscilla

    1983-10-01

    FALL 1983 25 El espacio dramtico como signo: La noche de los asesinos de Jos Triana Priscilla Melndez Las nuevas corrientes que caracterizan el teatro moderno han demostrado una profunda preocupacin por concebir el acto teatral en todas sus... in the concrete domain (p. 72). La importancia de la estructura en La noche de los asesinos radica fundamen talmente en lo que se concibe como el espacio dramtico de la obra, que a un primer nivel se trata de un espacio fsicamente cerrado en el cual...

  12. Risk Factors for Eating Disorders

    ERIC Educational Resources Information Center

    Striegel-Moore, Ruth H.; Bulik, Cynthia M.

    2007-01-01

    The authors review research on risk factors for eating disorders, restricting their focus to studies in which clear precedence of the hypothesized risk factor over onset of the disorder is established. They illustrate how studies of sociocultural risk factors and biological factors have progressed on parallel tracks and propose that major advances

  13. Atomic Scattering Factors

    NSDL National Science Digital Library

    From the Lawrence Berkeley Laboratory's Center for X-Ray Optics, these "atomic scattering factors are based upon photoabsorption measurements of elements in their elemental state." These easy-to-use tables allow users to search out atomic scattering factor data by element and look up the x-ray properties of elements, the index of refraction for a compound material, the x-ray attenuation length of a solid, the x-ray transmission of a solid or a gas, and more. Most of the tables are accessed by way of an online query form with variables such as material, density, and photon energy range entered by the user. Most outputs come in plot form for quick viewing, or results may be retrieved as a text or postscript file for use with a personal plotting software.

  14. Prognostic factors for melanoma.

    PubMed

    Wisco, Oliver J; Sober, Arthur J

    2012-07-01

    The current melanoma staging system, as defined by the American Joint Committee on Cancer (AJCC), is the standard by which melanoma prognosis is determined. This article focuses on the components of the AJCC melanoma staging system regarding patient prognosis. In addition, this article summarizes the other commonly researched clinical and histologic melanoma prognostic factors and reviews the recent advancements in genetic biomarkers associated with prognosis. PMID:22800552

  15. The Fas Death Factor

    Microsoft Academic Search

    Shigekazu Nagata; Pierre Golstein

    1995-01-01

    Fas ligand (FasL), a cell surface molecule belonging to the tumor necrosis factor family, binds to its receptor Fas, thus inducing apoptosis of Fas-bearing cells. Various cells express Fas, whereas FasL is expressed predominantly in activated T cells. In the immune system, Fas and FasL are involved in down-regulation of immune reactions as well as in T cell-mediated cytotoxicity. Malfunction

  16. Factors Affecting Gummy Butter.

    E-print Network

    Leighton, R. E. (Rudolph Elmo); Moore, A. V.

    1952-01-01

    LIBRARY A. & M. COLLEGE OF TEXAS Factors Affecting Gummy Butter DIGEST Among the Southcentral States, Texas ranks next to Oklahoma and Kentucky in creamery butter production; in farm butter production Texas is third in the nation...-following Alabama and North Carolina. Second only to flavor in the importance of eating quality is the body of butter. Body is evaluated by the consumer by the manner in which the butter melts or spreads. It is often considered that cows eating cottonseed...

  17. Retroviral factors promoting infectivity.

    PubMed

    Cuccurullo, Emilia Cristiana; Valentini, Chiara; Pizzato, Massimo

    2015-01-01

    The ability of a virus particle to establish an infectious event is a fundamental property required for viral propagation and survival. Retrovirus invasion of target cells is a multistep process that begins with entry into the cytoplasm and culminates with the integration of the proviral genome into the host DNA. Along this journey, many obstacles await the retrovirus particle and undermine its infectivity. Host-cell barriers to retrovirus infection can either be basic structural components of the eukaryotic cell or specific antiretroviral activities developed by the cell to prevent the retroviral invasion. Resulting from a long host-parasite coevolution, retroviruses have developed auxiliary factors that promote infectivity by conferring the virion the ability to overcome several cellular obstacles, which interfere with the infection process. Here, we provide an overview of different retroviral auxiliary factors that promote virion infectivity, comparing their mechanism of action and highlighting common mechanistic strategies. Special attention is given to infectivity factors that remain enigmatic in the biology of retroviruses. PMID:25595806

  18. Risk factors for cancer

    SciTech Connect

    Lyman, G.H. (Medicine Service, H. Lee Moffitt Cancer Center, Tampa, FL (United States))

    1992-09-01

    It is no longer reasonable to divide cancers into those that are genetic in origin and those that are environmental in origin. With rare exception, carcinogenesis involves environmental factors that directly or indirectly exert a change in the cell's genome. Virtually all causes of cancer are multifactorial, sometimes involving an inherited predisposition to the carcinogenic effects of environmental factors, which include chemicals, ionizing radiation, and oncogenic virus. Carcinogenesis is a multistep process including induction, promotion, and progression. Initiation requires an irreversible change in the cellular genome, whereas promotion is commonly associated with prolonged and reversible exposure. Tumor progression results in genotypic and phenotypic changes associated with tumor growth, invasion, and metastasis. Most information on human cancer risk is based on epidemiologic studies involving both exposed and unexposed individuals. The quality of such studies depends on their ability to assess the strength of any association of exposure and disease and careful attention to any potential bias. Few cancers are inherited in a Mendelian fashion. Several preneoplastic conditions, however, are clearly inherited and several malignancies demonstrate weak familial patterns. Environmental factors may exert their effect on DNA in a random fashion, but certain consistent changes, including specific translocations of genetic information, are often found. Currently, there is great interest in the close proximity of certain oncogenes governing growth control to the consistent chromosomal changes observed. Such changes may represent a final common pathway of action for environmental carcinogens. Sufficient laboratory and epidemiologic evidence exists to establish a causal association of several chemical agents with cancer.

  19. Departamento de Matemticas Matemticas (CC. Qumicas) Ejercicios sobre derivacin: optimizacin

    E-print Network

    transporta paralela al suelo. 10. El propietario de un huerto de manzanas calcula que si siembra 24 rboles por acre, entonces cada rbos dar 600 manzanas por ao. Por cada tres rboles ms que se planten por acre, el nmero de manzanas disminuye en 12 al ao. Cuntos rboles debe plantar para obtener el mayor

  20. Ejercicios de "Teoria de conjuntos" Jose A. Alonso Jimenez

    E-print Network

    Alonso, José A.

    a (2) a b a b (3) (c a)[c b] a b 6.- Demostrar que 1. (a b) = ( a) ( b). 2. Si a y b son a = . Demostrar que: (1) {b c : b a} = c ( a) (2) {b c : b a} = c ( a) 8.- Sean a y b conjuntos. Estudiar en qu condiciones es cierta la siguiente igualdad: a ( b) = {a c : c b} 9.- Probar que si a, b y c

  1. Ejercicios de "Teoria de conjuntos" Jose A. Alonso Jimenez

    E-print Network

    Alonso, José A.

    , 2}. Calcular: x, x, x x - x , x - x 4. (P(2) - 2). 2.- Sean a y b conjuntos. Probar que: (1) b a a b a (2) a b a b (3) (x(x a x b)) a b 3.- Sean a y b conjuntos. Probar que: 1. (a b) = ( a) ( b). 2. Si a y b son conjuntos no vac´ios, entonces (ab) = ( a)( b). ¿Qu´e podemos asegurar si a ´o b

  2. From compatible factorization to near-compatible factorization

    NASA Astrophysics Data System (ADS)

    Aldiabat, Raja'i.; Ibrahim, Haslinda

    2014-12-01

    A compatible factorization of order ?, is an ? ?-1/2 array in which the entries in row i form a near-one-factor with focus i, and the triples associated with the rows contain no repetitions. In this paper, we aim to amend this compatible factorization so that we can display ?(?-1)/2 - 2?/3 triples with the minimum repeated triples. Throughout this paper we propose a new type of factorization called near-compatible factorization. First, we present the compatible factorization towards developing a near-compatible factorization. Second, we discuss briefly the necessary and sufficient conditions for the existence of near-compatible factorization. Then, we exemplify the construction for case ? = 9 as a groundwork in developing near-compatible factorization.

  3. Mtodo de Fibonacci Como no mtodo da "Golden Section" o procedimento de procura de Fibonacci faz

    E-print Network

    Instituto de Sistemas e Robotica

    Mtodo de Fibonacci Como no mtodo da "Golden Section" o procedimento de procura de Fibonacci faz incerteza varia duma iterao para outra. O procedimento baseado na sequncia de Fibonacci Fn{ } definida acontece com os mtodos da procura dicotmica e de "Golden section", o mtodo de Fibonacci requer que o

  4. COMPETENCIA TEXTUAL1 Y ENSEANZA DEL ESPAOL COMO SEGUNDA LENGUA 2

    Microsoft Academic Search

    ROCO LINEROS QUINTERO

    Contrariamente a lo que parece sugerir el ttulo de esta investigacin, su objetivo no es convertirse en una de las muchas aportaciones, ms o menos eruditas, que relacionan la enseanza de segundas lenguas con la capacidad de ejercer, eficazmente, un ilimitado nmero de estrategias y habilidades tanto psicolgicas como educativas. Con sus consiguientes avances y retrocesos, el pensamiento educativo nos

  5. Interface observation of heat-treated Co/Mo2C multilayers

    NASA Astrophysics Data System (ADS)

    Yuan, Yanyan; Le Guen, Karine; Andr, Jean-Michel; Mny, Christian; Ulhaq, Corinne; Galtayries, Anouk; Zhu, Jingtao; Wang, Zhanshan; Jonnard, Philippe

    2015-03-01

    We study the interface evolution of a series of periodic Co/Mo2C multilayers as a function of the annealing temperature up to 600 C. Different complementary techniques are implemented to get information on the phenomenon taking place at the interfaces of the stack. The periodical structure of Co/Mo2C multilayer is proven by time-of-flight secondary ion mass spectrometry (ToF-SIMS) depth profiles which demonstrate the formation of an oxide layer at both air/stack and stack/substrate interfaces. From Nuclear magnetic resonance (NMR) spectra, we observed the intermixing phenomenon of Co and C atoms for the as-deposited sample, and then at annealing temperature above 300 C Co and C atoms separate from their mixed regions. Comparison of NMR results between Co/Mo2C and Co/C references confirms this phenomenon. This is in agreement with X-ray emission spectroscopy (XES) measurements. Furthermore the calculation of the Co-C, Co-Mo and Mo-C mixing enthalpy using Miedema's model gives a proof of the demixing of Co and C atoms present within the stacks above 300 C. From the transmission electron microscopy (TEM) analysis, we found the presence of some crystallites within the as-deposited sample as well as the mainly amorphous nature of all layers. This is confirmed using X-ray diffraction (XRD) patterns which also demonstrate the growth of crystallites induced upon annealing.

  6. PROPOSTA CURSO DE VERN: A DIVULGACIN COMO PONTE ENTRE CIENCIA E SOCIEDADE

    E-print Network

    Fraguela, Basilio B.

    PROPOSTA CURSO DE VERN: A DIVULGACIN COMO PONTE ENTRE CIENCIA E SOCIEDADE 2 e 3 de xullo de 2014 BEATRIZ HERVELLA NOGUEIRA. Licenciada en Ciencias Fsicas pola USC e cofundadora de 4gotas atmosfera y CONFERENCIA - ESPECTCULO RICARDO PAREDES PAMPN. Licenciado en Ciencias Fsicas pola USC e profesor de

  7. EL WIKI COMO RECURSO PARA DESARROLLAR COMPETENCIAS EN EL PROCESO DE ENSEANZA-APRENDIZAJE

    Microsoft Academic Search

    Mabel Lpez Garca; Jos Mara Souvirn Morenilla

    2010-01-01

    En el presente trabajo se analiza la utilidad de las tecnologas de la informacin y la comunicacin (TIC), y especficamente del Wiki, como herramienta para el modelo de enseanza-aprendizaje derivado del Espacio Europeo de Educacin Superior (EEES). Se realiza una aproximacin al significado del EEES y al modelo de enseanza que propone, en el que lo relevante no es tanto

  8. LAS INTELIGENCIAS EMOCIONAL Y SOCIAL COMO COMPLEMENTO A LA RACIONAL PARA FACILITAR EL DESARROLLO PROFESIONAL

    Microsoft Academic Search

    Jos Manuel Garca Lpez

    2010-01-01

    En este documento se analiza lo importante que resulta el tener un buen manejo de las emociones y de las relaciones sociales o interpersonales como estrategia para tener xito personal o profesional, dado que en la actualidad son dos caractersticas adicionales a la inteligencia racional muy valoradas en las organizaciones y que permiten a los individuos tener mayores o mejores

  9. La hipnosis como adjunto en el tratamiento del hbito de fumar. Estudio de caso

    Microsoft Academic Search

    Mara Elena; Mendoza Figueroa

    2000-01-01

    Se presenta el caso de una paciente de 33 aos con dependencia a la nicotina que lle vaba 9 aos fu- mando una media de 35 cigarrillos diarios. Intent dejarlo hace 3 aos pero tuvo una recada a los seis meses por problemas de ansiedad y continu con su adiccin. El tr atamiento tuvo como objetivo que la paciente dejara

  10. CURSO DE INICIACIN A LA ENSEANZA DEL ESPAOL COMO LENGUA EXTRANJERA-FORMACIN DE PROFESORADO

    E-print Network

    CURSO DE INICIACIN A LA ENSEANZA DEL ESPAOL COMO LENGUA EXTRANJERA-FORMACIN DE PROFESORADO o grado)*: o En curso (especificar curso y carrera)*: Otros: *Ser necesario acreditar los estudios curso. FORMALIZACIN DE LA MATRCULA Para formalizar la matrcula del curso es necesario realizar el

  11. El estudio de caso como metodologa de investigacin: teora, mecanismos causales, validacin

    Microsoft Academic Search

    Enrique Yacuzzi

    2005-01-01

    Este trabajo presenta el mtodo del caso como herramienta de investigacin en las ciencias sociales. Desde el diseo hasta la presentacin de sus resultados, el mtodo est estrechamente vinculado con la teora. Una teora es una respuesta a una pregunta del tipo \\

  12. LA BIBLIOTECA UNIVERSITARIA COMO APOYO AL APRENDIZAJE EN EL ESPACIO EUROPEO DE ENSEANZA SUPERIOR

    E-print Network

    Granada, Universidad de

    LA BIBLIOTECA UNIVERSITARIA COMO APOYO AL APRENDIZAJE EN EL ESPACIO EUROPEO DE ENSEANZA SUPERIOR proceso de transformacin ante el Espacio Europeo de Educacin Superior (EEES). Este nuevo marco implica bibliotecas universitarias deben adaptar sus espacios y servicios a las nuevas necesidades docentes

  13. Avaliao tardia por tomografia computadorizada espiral de enxertos de pericrdio bovino liso como substitutos articos

    Microsoft Academic Search

    Renato A. K. Kalil; Carlos Jader Feldman; Fernando W. B. Ludwig; Alessandro D'Avila da Silva; Paulo Roberto Prates; Joo R. M. Sant'Anna; Ivo A. Nesralla

    1997-01-01

    Objetivo - Avaliar, morfologicamente, por tomo- grafia computadorizada espiral, enxertos de pericrdio bovino liso empregados como substitutos articos. Mtodos - Dez pacientes foram submetidos a exame por tomografia computadorizada espiral para reconsti- tuio da imagem dos enxertos. Os critrios de seleo fo- ram tempo de seguimento superior a 2 anos, enxertos de pericrdio liso no revestido, implantados na aorta ascen-

  14. Hydrologic flowpaths and biogeochemical cycles in the subalpine Como Creek catchment, Colorado Front Range, USA

    NASA Astrophysics Data System (ADS)

    Cowie, R. M.; Williams, M. W.; Zeliff, M. M.; Parman, J.

    2011-12-01

    An outstanding question for snowmelt-dominated watersheds of the western US are the responses of biogeochemical processes to two major drivers of environmental change: directional changes in climate and increasing dissolved inorganic nitrogen (DIN) deposition in wetfall. In the Colorado Front Range, atmospheric deposition of DIN has increased several-fold in the last 25 years. In response, nitrate concentrations at the alpine Green Lakes 4 (GL4) catchment have increased from 1985 to 2009 by 0.27 ?eq L-1 yr-1. In contrast, we see no directional change in either nitrate concentrations or fluxes in the subalpine Como Creek catchment. We hypothesize that differences in surface/groundwater interactions result in the differing behavior of stream nitrate between the alpine and subalpine catchments that are receiving similar amounts of DIN from atmospheric deposition. For both basins we sampled precipitation, snowpack, snowmelt, surface water, and subsurface waters. All water samples are analyzed for geochemical, nutrient and isotopic (?18O, ?D) composition. Stream chemistry data from the last ten years at Como Creek show increases in nitrate concentration during baseflow conditions and then a sharp decline during snowmelt. In contrast, in the alpine basin there is sharp increase in surface water nitrate during snowmelt. Hydrograph separation at the alpine GL4 using end member mixing analysis (EMMA) shows that stream flow is a mixture of three components, groundwater, talus, and new snowmelt that each contribute to roughly a third of discharge, with talus flow supplying the majority of nitrate. In contrast, and somewhat surprisingly, EMMA shows that for the subalpine Como Creek basin, annual streamflow is a mixture of only two components, groundwater and new snowmelt. During snowmelt the groundwater and snow contributions are nearly equal and subsurface flows dominate the remainder of the year. Newly installed piezometers at Como Creek provide evidence that the basin is largely a losing reach during snowmelt, with water levels in the piezometers increasing 5-7 m. After peak snowmelt however, Como Creek becomes a gaining stream, with piezometer levels dropping. Thus, both EMMA and piezometers show that surface-groundwater interactions are tightly coupled during snowmelt, with snowmelt at Como first replenishing the subsurface water deficit and increasing groundwater levels before contributing to discharge. Thus, in contrast to the alpine GL4 basin, DIN released in snowmelt is assimilated belowground as snowmelt infiltrates the subsurface in the subalpine basin. Interestingly, at the subalpine Como Creek basin, isotopic and geochemical solute concentrations undergo shifts during periods of winter baseflow prior to snowmelt. In winter much of the stream is frozen and we hypothesize that cryo-concentration of solutes and fractionation of isotopes may influence the concentrations of winter stream samples.

  15. Trabajos de fin de curso Economia y Finanzas

    E-print Network

    Fernndez Gallardo, Pablo

    . (Pueden servir como referencia los ejercicios que hicimos en el laboratorio). Se analizaran, en paralelo pide montar un arbol binomial tipo Jarrow-Rudd, con paso t = 1/12. (Pueden servir como referencia los

  16. Neutron quality factor

    SciTech Connect

    NONE

    1995-06-01

    Both the International Commission on Radiological Protection (ICRP) and the National Council on Radiation Protection and Measurements (NCRP) have recommended that the radiation quality weighting factor for neutrons (Q{sub n}, or the corresponding new modifying factor, w{sub R}) be increased by a value of two for most radiation protection practices. This means an increase in the recommended value for Q{sub n} from a nominal value of 10 to a nominal value of 20. This increase may be interpreted to mean that the biological effectiveness of neutrons is two times greater than previously thought. A decision to increase the value of Q{sub n} will have a major impact on the regulations and radiation protection programs of Federal agencies responsible for the protection of radiation workers. Therefore, the purposes of this report are: (1) to examine the general concept of {open_quotes}quality factor{close_quotes} (Q) in radiation protection and the rationale for the selection of specific values of Q{sub n}; and (2) to make such recommendations to the Federal agencies, as appropriate. This report is not intended to be an exhaustive review of the scientific literature on the biological effects of neutrons, with the aim of defending a particular value for Q{sub n}. Rather, the working group examined the technical issues surrounding the current recommendations of scientific advisory bodies on this matter, with the aim of determining if these recommendations should be adopted by the Federal agencies. Ultimately, the group concluded that there was no compelling basis for a change in Q{sub n}. The report was prepared by Federal scientists working under the auspices of the Science Panel of the Committee on Interagency Radiation Research and Policy Coordination (CIRRPC).

  17. Factors and Multiples Puzzle

    NSDL National Science Digital Library

    This puzzle, played with cards on a board (downloadable file), provides an interesting context in which students can apply their knowledge of number properties. Students attempt to arrange 25 numbers and 10 property headings into a 5 by 5 grid so that each number satisfies two conditions. Properties addressed include primes, square and triangular numbers, specific sets of multiples and factors, and parity. It can be worked individually or in small groups cooperatively. The Teachers' Notes page offers suggestions for implementation, discussion questions, ideas for extension and support, and links to an article, "Using Games in the Classroom" (catalogued separately).

  18. Nucleon elastic form factors

    SciTech Connect

    D. Day

    2007-03-01

    The nucleon form factors are still the subject of active investigation even after an experimental effort spanning 50 years. This is because they are of critical importance to our understanding of the electromagnetic properties of nuclei and provide a unique testing ground for QCD motivated models of nucleon structure. Progress in polarized beams, polarized targets and recoil polarimetry have allowed an important and precise set of data to be collected over the last decade. I will review the experimental status of elastic electron scattering from the nucleon along with an outlook for future progress.

  19. Factor-multiple Chains

    NSDL National Science Digital Library

    This problem offers opportunities for students to reinforce their understanding of factors and multiples and provides them the chance to justify their solutions. The goal is for the students to create number chains of four whole numbers that can range from 2 to 100 and each consecutive number is a multiple of the previous number. The Teachers' Notes page offers suggestions for implementation, key discussion questions, ideas for extension and support, and a link to a spreadsheet for students to experiment with placing numbers in specific boxes in the chain.

  20. Factors in risk perception

    PubMed

    Sjoberg

    2000-02-01

    Risk perception is a phenomenon in search of an explanation. Several approaches are discussed in this paper. Technical risk estimates are sometimes a potent factor in accounting for perceived risk, but in many important applications it is not. Heuristics and biases, mainly availability, account for only a minor portion of risk perception, and media contents have not been clearly implicated in risk perception. The psychometric model is probably the leading contender in the field, but its explanatory value is only around 20% of the variance of raw data. Adding a factor of "unnatural risk" considerably improves the psychometric model. Cultural Theory, on the other hand, has not been able to explain more than 5-10% of the variance of perceived risk, and other value scales have similarly failed. A model is proposed in which attitude, risk sensitivity, and specific fear are used as explanatory variables; this model seems to explain well over 30-40% of the variance and is thus more promising than previous approaches. The model offers a different type of psychological explanation of risk perception, and it has many implications, e.g., a different approach to the relationship between attitude and perceived risk, as compared with the usual cognitive analysis of attitude. PMID:10795334

  1. Factors regulating cheese shreddability.

    PubMed

    Childs, J L; Daubert, C R; Stefanski, L; Foegeding, E A

    2007-05-01

    Two sets of cheeses were evaluated to determine factors that affect shred quality. The first set of cheeses was made up of 3 commercial cheeses, Monterey Jack, Mozzarella, and process. The second set of cheeses was made up of 3 Mozzarella cheeses with varying levels of protein and fat at a constant moisture content. A shred distribution of long shreds, short shreds, and fines was obtained by shredding blocks of cheese in a food processor. A probe tack test was used to directly measure adhesion of the cheese to a stainless-steel surface. Surface energy was determined based on the contact angles of standard liquids, and rheological characterization was done by a creep and recovery test. Creep and recovery data were used to calculate the maximum and initial compliance and retardation time. Shredding defects of fines and adhesion to the blade were observed in commercial cheeses. Mozzarella did not adhere to the blade but did produce the most fines. Both Monterey Jack and process cheeses adhered to the blade and produced fines. Furthermore, adherence to the blade was correlated positively with tack energy and negatively with retardation time. Mozzarella cheese, with the highest fat and lowest protein contents, produced the most fines but showed little adherence to the blade, even though tack energy increased with fat content. Surface energy was not correlated with shredding defects in either group of cheese. Rheological properties and tack energy appeared to be the key factors involved in shredding defects. PMID:17430914

  2. Determining the Number of Factors in Approximate Factor Models

    Microsoft Academic Search

    Jushan Bai; Serena Ng

    2002-01-01

    In this paper we develop some statistical theory for factor models of large dimen- sions. The focus is the determination of the number of factors, which is an unresolved issue in the rapidly growing literature on multifactor models. We propose a panel Cp criterion and show that the number of factors can be consistently estimated using the criterion. The theory

  3. Factors affecting growth factor activity in goat milk.

    PubMed

    Wu, F Y; Tsao, P H; Wang, D C; Lin, S; Wu, J S; Cheng, Y K

    2006-06-01

    Growth factors that are present in goat milk may be responsible for its beneficial effects on the digestive system as described in ancient Chinese medical texts. To develop a nutraceutical product rich in growth factors for promoting gastrointestinal health, it is essential to collect milk with consistently high growth factor activity. Therefore, we investigated the factors affecting growth factor activity in goat milk. Among the 5 breeds of dairy goats tested, milk from Nubian goats had the highest growth factor activity. Tight-junction leakage induced by a 24-h milking interval did not increase growth factor activity in the milk. Milk collected from pregnant does had a significantly higher growth factor activity than milk collected postpartum. Growth factor activity decreased during the first 8 wk of lactation, fluctuated thereafter, and then increased dramatically after natural mating. During wk 1 to 8, growth factor activity was inversely correlated with milk yield and week of lactation. No correlation was observed during wk 9 to 29. After natural mating of the goats, the growth factor activity in the milk correlated significantly with somatic cell count and conductivity (a measure of membrane permeability), and correlated inversely with milk yield. Based on the above data, goat milk with higher growth factor activity could be selectively collected from Nubian pregnant does. PMID:16702258

  4. Determining the Number of Factors in Approximate Factor Models

    Microsoft Academic Search

    Jushan Bai; Serena Ng

    2000-01-01

    In this paper we develop some econometric theory for factor models of large dimensions. The focus is the determination of the number of factors, which is an unresolved issue in the rapidly growing literature on multifactor models. We propose some panel C(p) criteria and show that the number of factors can be consistently estimated using the criteria. The theory is

  5. Activation of Factor IX by the Reaction Product of Tissue Factor and Factor VII: Additional Pathway for Initiating Blood Coagulation

    Microsoft Academic Search

    Bjarne Osterud; Samuel I. Rapaport

    1977-01-01

    A study was carried out on mechanisms, independent of activated Factor XI, capable of activating Factor IX. The reaction product of tissue factor and Factor VII functioned as a potent Factor IX activator in the assay system used. Activated Factor IX itself activated Factor X; thrombin failed to activate Factor IX. Sodium dodecyl sulfate\\/polyacrylamide gel electrophoresis confirmed that the reaction

  6. Factors affecting dystocia in cattle.

    PubMed

    Zaborski, D; Grzesiak, W; Szatkowska, I; Dybus, A; Muszynska, M; Jedrzejczak, M

    2009-06-01

    The paper reviews the various factors affecting dystocia in cattle. It is based mainly on the recent studies found in the literature of the subject but refers occasionally to some older papers as well. The factors are grouped into four main categories: direct factors, phenotypic factors related to calf and cow, non-genetic and genetic factors. The first group includes malpresentations and uterine torsion. The second one includes: calf birth weight, multiple calvings, perinatal mortality, cow pelvic area, cow body weight and body condition at calving, gestation length. The non-genetic factors are: cow age and parity, year and season of calving, place of calving, maintenance practises, disorders, calf sex and nutrition. Other non-genetic factors are the level of hormones in the periparturient period, in vitro production of embryos and embryo cloning. Finally, the genotypes of cow, bull and calf, inbreeding, muscular hypertrophy, selection and quantitative trait loci form the fourth group of genetic factors. PMID:19055561

  7. The 'cancer cachectic factor'.

    PubMed

    Tisdale, Michael J

    2003-02-01

    The object of this study was to summarize information on catabolic factors produced by tumours which lead to tissue catabolism in cancer cachexia and to use this information for the development of effective therapy. The study population was made up of patients with cancer cachexia and weight loss greater than 1 kg month(-1). They had a varied range of carcinomas, particularly pancreatic, but also of the breast, ovary, lung, colon and rectum. Cachectic factors were isolated by standard biochemical methods, and the mechanism of tissue catabolism was evaluated in vitro and in vivo. We isolated a 24-kDa sulphated glycoprotein produced by cachexia-inducing murine and human tumours, which induces catabolism of myofibrillar proteins in skeletal muscle and for this reason has been named proteolysis-inducing factor (PIF). PIF was shown to be present in a diverse range of carcinomas in patients whose rate of weight loss exceeded 1.0 kg month(-1). Administration of PIF to normal mice produced a rapid decrease in body weight, which arose primarily from a loss of skeletal muscle, accompanied by increased mRNA levels for ubiquitin, the ubiquitin-carrier protein (E2(14k)), and proteasome subunits. This suggests that PIF induces protein catabolism through an increased expression of the key components of the ATP-ubiquitin-dependent proteolytic pathway. The action of PIF was attenuated both in vitro and in vivo by eicosapentaenoic acid (EPA). Oral EPA has been found to stabilize the body weight of patients with advanced pancreatic cancer and, when combined with an energy- and protein-rich nutritional supplement, to produce weight gain arising solely from an increase in lean body mass. Nutritional supplementation alone is unable to reverse the process of muscle wasting in cancer patients, since this arises from activation of the ubiquitin proteasome pathway by PIF, which is independent of nutrient intake. EPA is able to down-regulate the increased expression of this pathway and prevents muscle wasting in cancer patients. PMID:12560934

  8. Alejarse como proceso social: nios y ancianos abandonados en Ayacucho1

    PubMed Central

    Leinaweaver, Jessaca

    2013-01-01

    En investigaciones previas sobre el acogimiento familiar y la adopcin en Ayacucho, se ha podido descubrir cmo los ayacuchanos adquieren y producen relaciones sociales. Mientras negocian creativamente los discursos y espacios construidos simultneamente por instituciones, comunidades, y estructuras sociales, van adquiriendo nuevas formas de relacionarse. Este artculo discute el proceso opuesto: el deshacerse de relaciones de parentesco, y el proceso social del abandono o alejamiento. Cuando se aleja a una persona de su familia o su comunidad, los que se quedan en ella llegan a entenderse como ciertos tipos de personas. En los estudios de caso discutidos aqu, recopilados a travs de una detallada y cuidadosa observacin participante y de entrevistas etnogrficas grabadas entre 2001 y 2007, se puede ver cmo, despus de un alejamiento social, los individuos que alejan se reinterpretan como sujetos que se encuentran superndose o volvindose modernos, o bien sacrificndose. PMID:25177044

  9. Deactivation and attrition of CoMo catalyst during H-Coal operations

    Microsoft Academic Search

    C. C. Kang; E. S. Johanson

    1977-01-01

    The observed causes for the deactivation of the Co-Mo catalyst in the H-Coal process are related to sintering, metal deposition, and carbon deposition. The relative importance of these effects depends on the type of coal employed and the process conditions. In the H-Coal process, which has been under development for over ten years, coal is dried, pulverized, and slurried with

  10. K.K. Gan Como03 1 The Ohio State University

    E-print Network

    Gan, K. K.

    Optical Receiver IC 40 MHz clock command BPM #12;K.K. Gan Como03 7 l Training period: ~25 ms of 20 MHz.25 mm CMOS rad-hard process (2.5 V) q enclosed layout transistors and guard rings for improved radiation hardness l IBM 5e: April 2003 engineering run q convert 3-layer to 5-layer layout for submission with pixel

  11. Psychosomatic factors in pruritus.

    PubMed

    Tey, Hong Liang; Wallengren, Joanna; Yosipovitch, Gil

    2013-01-01

    Pruritus and psyche are intricately and reciprocally related, with psychophysiological evidence and psychopathological explanations helping us to understand their complex association. Their interaction may be conceptualized and classified into 3 groups: pruritic diseases with psychiatric sequelae, pruritic diseases aggravated by psychosocial factors, and psychiatric disorders causing pruritus. Management of chronic pruritus is directed at treating the underlying causes and adopting a multidisciplinary approach to address the dermatologic, somatosensory, cognitive, and emotional aspects. Pharmcotherapeutic agents that are useful for chronic pruritus with comorbid depression and/or anxiety comprise selective serotonin reuptake inhibitors, mirtazapine, tricyclic antidepressants (amitriptyline and doxepin), and anticonvulsants (gabapentin, pregabalin); the role of neurokinin receptor-1 antagonists awaits verification. Antipsychotics are required for treating itch and formication associated with schizophrenia and delusion of parasitosis (including Morgellons disease). PMID:23245971

  12. Wave friction factor rediscovered

    NASA Astrophysics Data System (ADS)

    Le Roux, J. P.

    2012-02-01

    The wave friction factor is commonly expressed as a function of the horizontal water particle semi-excursion ( A wb) at the top of the boundary layer. A wb, in turn, is normally derived from linear wave theory by {{U_{{wb}}/T_{{w}}}}{{2? }} , where U wb is the maximum water particle velocity measured at the top of the boundary layer and T w is the wave period. However, it is shown here that A wb determined in this way deviates drastically from its real value under both linear and non-linear waves. Three equations for smooth, transitional and rough boundary conditions, respectively, are proposed to solve this problem, all three being a function of U wb, T w, and ?, the thickness of the boundary layer. Because these variables can be determined theoretically for any bottom slope and water depth using the deepwater wave conditions, there is no need to physically measure them. Although differing substantially from many modern attempts to define the wave friction factor, the results coincide with equations proposed in the 1960s for either smooth or rough boundary conditions. The findings also confirm that the long-held notion of circular water particle motion down to the bottom in deepwater conditions is erroneous, the motion in fact being circular at the surface and elliptical at depth in both deep and shallow water conditions, with only horizontal motion at the top of the boundary layer. The new equations are incorporated in an updated version (WAVECALC II) of the Excel program published earlier in this journal by Le Roux et al. Geo-Mar Lett 30(5): 549-560, (2010).

  13. Helicopter Human Factors

    NASA Technical Reports Server (NTRS)

    Hart, Sandra G.; Sridhar, Banavar (Technical Monitor)

    1995-01-01

    Even under optimal conditions, helicopter flight is a most demanding form of human-machine interaction, imposing continuous manual, visual, communications, and mental demands on pilots. It is made even more challenging by small margins for error created by the close proximity of terrain in NOE flight and missions flown at night and in low visibility. Although technology advances have satisfied some current and proposed requirements, hardware solutions alone are not sufficient to ensure acceptable system performance and pilot workload. However, human factors data needed to improve the design and use of helicopters lag behind advances in sensor, display, and control technology. Thus, it is difficult for designers to consider human capabilities and limitations when making design decisions. This results in costly accidents, design mistakes, unrealistic mission requirements, excessive training costs, and challenge human adaptability. NASA, in collaboration with DOD, industry, and academia, has initiated a program of research to develop scientific data bases and design principles to improve the pilot/vehicle interface, optimize training time and cost, and maintain pilot workload and system performance at an acceptable level. Work performed at Ames, and by other research laboratories, will be reviewed to summarize the most critical helicopter human factors problems and the results of research that has been performed to: (1) Quantify/model pilots use of visual cues for vehicle control; (2) Improve pilots' performance with helmet displays of thermal imagery and night vision goggles for situation awareness and vehicle control; (3) Model the processes by which pilots encode maps and compare them to the visual scene to develop perceptually and cognitively compatible electronic map formats; (4) Evaluate the use of spatially localized auditory displays for geographical orientation, target localization, radio frequency separation; (5) Develop and flight test control/display concepts; (6) Quantify, model, predict, and improve pilots, workload-management strategies; and (7) Design computer-game trainers to reduce training time and cost.

  14. Sparse Bayesian infinite factor models

    Microsoft Academic Search

    A. Bhattacharya; D. B. Dunson

    2011-01-01

    We focus on sparse modelling of high-dimensional covariance matrices using Bayesian latent factor models. We propose a multiplicative gamma process shrinkage prior on the factor loadings which allows introduction of infinitely many factors, with the loadings increasingly shrunk towards zero as the column index increases. We use our prior on a parameter-expanded loading matrix to avoid the order dependence typical

  15. FACTOR FINDER CD-ROM

    EPA Science Inventory

    The Factor Finder CD-ROM is a user-friendly, searchable tool used to locate exposure factors and sociodemographic data for user-defined populations. Factor Finder improves the exposure assessors and risk assessors (etc.) ability to efficiently locate exposure-related informatio...

  16. Automatic test factoring for java

    Microsoft Academic Search

    David Saff; Shay Artzi; Jeff H. Perkins; Michael D. Ernst

    2005-01-01

    Test factoring creates fast, focused unit tests from slow system-wide tests; each new unit test exercises only a subset of the functionality exercised by the system test. Augment- ing a test suite with factored unit tests should catch errors earlier in a test run. One way to factor a test is to introduce mock objects. If a test exercises a

  17. Sample size in factor analysis

    Microsoft Academic Search

    Robert C. MacCallum; Keith F. Widaman; Shaobo Zhang; Sehee Hong

    1999-01-01

    In the factor analysis literature, much attention has be;;n given to the issue of sample size. It is widely understood that the use of larger samples in applica- tions of factor analysis tends to provide results such that sample factor loadings are more precise estimates of population loadings and are also more stable, or les s variable, across repeated sampling.

  18. Topics in Factor Analysis II.

    ERIC Educational Resources Information Center

    Tucker, Ledyard R.; And Others

    Three topics in factor analysis are covered: a) a reliability coefficient for assessing the quality of a maximum likelihood factor analysis, b) an application of three-mode factor analysis to serial learning data, showing variations in learning curves over stages of learning and individuals, and c) the use of personal probability functions to

  19. Phonological Awareness: Factors of Influence

    ERIC Educational Resources Information Center

    Frohlich, Linda Paulina; Petermann, Franz; Metz, Dorothee

    2013-01-01

    Early child development is influenced by various genetic and environmental factors. This study aims to identify factors that affect the phonological awareness of preschool and first grade children. Based on a sample of 330 German-speaking children (mean age = 6.2 years) the following domains were evaluated: Parent factors, birth and pregnancy,

  20. Vector meson electromagnetic form factors

    E-print Network

    B. G. Lasscock; J. Hedditch; D. B. Leinweber; A. G. Williams

    2006-11-23

    The charge, magnetic and quadrupole form factors of vector mesons and the charge form factor of pseudo-scalar mesons are calculated in quenched lattice QCD. The charge radii and magnetic moments are derived. The quark sector contributions to the form factors are calculated separately and we highlight the environmental sensitivity of the light-quark contribution to charge radii.

  1. Factor Analysis via Components Analysis

    ERIC Educational Resources Information Center

    Bentler, Peter M.; de Leeuw, Jan

    2011-01-01

    When the factor analysis model holds, component loadings are linear combinations of factor loadings, and vice versa. This interrelation permits us to define new optimization criteria and estimation methods for exploratory factor analysis. Although this article is primarily conceptual in nature, an illustrative example and a small simulation show

  2. Factor Analysis of Intern Effectiveness

    ERIC Educational Resources Information Center

    Womack, Sid T.; Hannah, Shellie Louise; Bell, Columbus David

    2012-01-01

    Four factors in teaching intern effectiveness, as measured by a Praxis III-similar instrument, were found among observational data of teaching interns during the 2010 spring semester. Those factors were lesson planning, teacher/student reflection, fairness & safe environment, and professionalism/efficacy. This factor analysis was as much of a

  3. Transfer factors: identification of conserved sequences in transfer factor molecules.

    PubMed Central

    Kirkpatrick, C. H.

    2000-01-01

    BACKGROUND: Transfer factors are small proteins that "transfer" the ability to express cell-mediated immunity from immune donors to non-immune recipients. We developed a process for purifying specific transfer factors to apparent homogeneity. This allowed us to separate individual transfer factors from mixtures containing several transfer factors and to demonstrate the antigen-specificity of transfer factors. Transfer factors have been shown to be an effective means for correction of deficient cellular immunity in patients with opportunistic infections, such as candidiasis or recurrent Herpes simplex and to provide prophylactic immunity against varicella-zoster in patients with acute leukemia. MATERIALS AND METHODS: Transfer factors of bovine and murine origin were purified by affinity chromatography and high performance liquid chromatography. Cyanogen bromide digests were sequenced. The properties of an apparently conserved sequence on expression of delayed-type hypersensitivity by transfer factor recipients were assessed. RESULTS: A novel amino acid sequence, LLYAQDL/VEDN, was identified in each of seven transfer factor preparations. These peptides would not transfer expression of delayed-type hypersensitivity to recipients, which indicates that they are not sufficient for expression of the specificity or immunological properties of native transfer factors. However, administration of the peptides to recipients of native transfer factors blocked expression of delayed-type hypersensitivity by the recipients. The peptides were not immunosuppressive. CONCLUSIONS: These findings suggest that the peptides may represent the portion of transfer factors that binds to the "target cells" for transfer factors. Identification of these cells will be helpful in defining the mechanisms of action of transfer factors. PMID:10949913

  4. Meu trabalho como ornitloga abrange reas do comportamento animal, distribuies geogrficas e estudos sobre ecologia de populaes, incluindo biologia

    E-print Network

    Hrbek, Tomas - Department of Biology, Universidad de Puerto Rico

    famlia Pipridae, como modelos. Estas aves frugvoras ocorrem somente em florestas Neotropicais, e formam de estudos sobre o comportamento de corte em si, estes pssaros so modelos para estudos de dinmica populacional em sistemas poligmicos, alm de estudos de interaes ecolgicas diversas, como a utilizao do

  5. Human Factors in Training

    NASA Technical Reports Server (NTRS)

    Barshi, Immanuel; Byme, Vicky; Arsintescu, Lucia

    2008-01-01

    Future space missions will be significantly longer than current Shuttle missions and new systems will be more complex than current systems. Increasing communication delays between crews and Earth-based support means that astronauts need to be prepared to handle the unexpected on their own. As crews become more autonomous, their potential span of control and required expertise must grow to match their autonomy. It is not possible to train for every eventuality ahead of time on the ground, or to maintain trained skills across long intervals of disuse. To adequately prepare NASA personnel for these challenges, new training approaches, methodologies, and tools are required. This research project aims at developing these training capabilities. Training efforts in FY07 strongly focused on crew medical training, but also began exploring how Space Flight Resource Management training for Mission Operations Directorate (MOD) Flight Controllers could be integrated with systems training for optimal Mission Control Center operations. Beginning in January 2008, the training research effort will include team training prototypes and tools. The Training Task addresses Program risks that lie at the intersection of the following three risks identified by the Project: 1) Risk associated with poor task design; 2) Risk of error due to inadequate information; 3) Risk associated with reduced safety and efficiency due to poor human factors design.

  6. Human Factors in Training

    NASA Technical Reports Server (NTRS)

    Barshi, Immanuel; Byrne, Vicky; Arsintescu, Lucia; Connell, Erin; Sandor, Aniko

    2009-01-01

    Future space missions will be significantly longer than current shuttle missions and new systems will be more complex than current systems. Increasing communication delays between crews and Earth-based support means that astronauts need to be prepared to handle the unexpected on their own. As crews become more autonomous, their potential span of control and required expertise must grow to match their autonomy. It is not possible to train for every eventuality ahead of time on the ground, or to maintain trained skills across long intervals of disuse. To adequately prepare NASA personnel for these challenges, new training approaches, methodologies, and tools are required. This research project aims at developing these training capabilities. By researching established training principles, examining future needs, and by using current practices in space flight training as test beds, both in Flight Controller and Crew Medical domains, this research project is mitigating program risks and generating templates and requirements to meet future training needs. Training efforts in Fiscal Year 08 (FY08) strongly focused on crew medical training, but also began exploring how Space Flight Resource Management training for Mission Operations Directorate (MOD) Flight Controllers could be integrated with systems training for optimal Mission Control Center (MCC) operations. The Training Task addresses Program risks that lie at the intersection of the following three risks identified by the Project: (1) Risk associated with poor task design (2) Risk of error due to inadequate information (3) Risk associated with reduced safety and efficiency due to poor human factors design

  7. Human Factors in Training

    NASA Technical Reports Server (NTRS)

    Barshi, Immanuel; Byrne, Vicky; Arsintescu, Lucia; Connell, Erin

    2010-01-01

    Future space missions will be significantly longer than current shuttle missions and new systems will be more complex than current systems. Increasing communication delays between crews and Earth-based support means that astronauts need to be prepared to handle the unexpected on their own. As crews become more autonomous, their potential span of control and required expertise must grow to match their autonomy. It is not possible to train for every eventuality ahead of time on the ground, or to maintain trained skills across long intervals of disuse. To adequately prepare NASA personnel for these challenges, new training approaches, methodologies, and tools are required. This research project aims at developing these training capabilities. By researching established training principles, examining future needs, and by using current practices in space flight training as test beds, both in Flight Controller and Crew Medical domains, this research project is mitigating program risks and generating templates and requirements to meet future training needs. Training efforts in Fiscal Year 09 (FY09) strongly focused on crew medical training, but also began exploring how Space Flight Resource Management training for Mission Operations Directorate (MOD) Flight Controllers could be integrated with systems training for optimal Mission Control Center (MCC) operations. The Training Task addresses Program risks that lie at the intersection of the following three risks identified by the Project: 1) Risk associated with poor task design; 2) Risk of error due to inadequate information; and 3) Risk associated with reduced safety and efficiency due to poor human factors design.

  8. [Hereditary factors in strabismus].

    PubMed

    Mvogo, C E; Ellong, A; Bella-Hiag, A L; Luma-Namme, H

    2001-01-01

    This retrospective study took place in the Ophthalmology Department of Douala General Hospital. The aim was to determine the importance of hereditary factors in a group of strabismic Cameroonians. In a series of 275 patients with strabismus, we found 79 familial cases (28.72%). Among them, 22.78% had more than one relative with squint and 75% had the same type of strabismus as their relative. There was no significant difference in the percentage of familial cases with regard to the type of strabismus, the sex, the mode of fixation and the impairment of ductions. As far as ametropias are concerned, only myopia showed a hereditary tendency in our series. The authors agree with the literature in that there is a significant hereditary component in the cause of strabismus, but its genetic sites are yet to be identified. There is strong hope in this direction with the decoding of the human genom and the advances in molecular biology. However, the study of familial cases is important since it allows high risk groups to be defined and screened. It thus makes it possible to successfully fight amblyopia through early detection and treatment. PMID:11861199

  9. Statistical distribution of factors and factor images in factor analysis of medical image sequences

    NASA Astrophysics Data System (ADS)

    Buvat, I.; Benali, H.; Di Paola, R.

    1998-06-01

    From a time or energy image sequence, factor analysis of medical image sequences (FAMIS) estimates factors, representing kinetics or spectra in a given physiological compartment, and associated factor images, showing the compartments corresponding to each curve. In this paper, we show that the statistical properties of factor images and associated factors can be determined using a well known result from elementary probability theory. Numerical experiments are conducted to demonstrate that the variance observed in factor images can be predicted when the statistical properties of the original data are known. It is shown how these theoretical results can be used to relax the non-negativity constraints during FAMIS oblique analysis and to improve the quantitative interpretation of the factor images by associating a confidence interval with each pixel value.

  10. Factors controlling testis descent.

    PubMed

    Hughes, Ieuan A; Acerini, Carlo L

    2008-12-01

    Descent of the testis from an intra-abdominal site in foetal life to an extracorporeal location after birth is a mandatory developmental process to ensure that the mature testis promotes normal spermatogenesis. The two phases of transabdominal and inguinoscrotal descent occur approximately during the first and last thirds of gestation respectively. Key anatomical events to release the testis from its urogenital ridge location and to guide the free gonad into the scrotum are the degeneration of the cranio-suspensory ligament and a thickening of the gubernaculum. Androgens play a role in both these processes, particularly with respect to enabling the testis to traverse the inguinal canal in the final phase of descent. Experiments in animals suggest that androgens mediate this effect via the release of calcitonin gene-related peptide by the genitofemoral nerve, but direct evidence for such a mechanism is lacking in humans. The transabdominal phase of descent is under the control of insulin-like 3 (INSL3), a product of the Leydig cells. Definitive evidence of its role in rodent testis descent is illustrated by the phenotype of bilateral cryptorchidism in Insl3-/- null mice. Circulating levels of INSL3 are higher in boys at puberty, are undetectable in girls and are lower in boys with undescended testes. A minority also have a mutation either in the INSL3 gene or affecting its receptor gene, relaxin/insulin-like family peptide receptor 2 (LGRF8). Other factors that may play a role in testis descent include the anti-Mullerian hormone and members of the HOX gene family. Evidence that the prevalence of undescended testis may be increasing provides a phenotypic readout for the effects of postulated chemicals in the environment interfering in some way with the action of factors that control testis descent. Epidemiological studies point to profound geographical variations in prevalence in countries such as Denmark and Finland. Associations have been found with levels of chemicals labelled as endocrine disruptors being higher in breast milk samples from mothers with cryptorchid boys when compared with controls. The adverse effects of these compounds (e.g. bisphenol A) can be replicated in the offspring of dams exposed during pregnancy. A sensitive marker of an anti-androgen effect of a compound is a reduction in the anogenital distance, an anthropometric measurement that is significantly greater in males compared with females. The observation of an association between the anogenital distance in infant boys and the level of pesticides in the urine of their mothers in late gestation indicates that this has the potential to be a useful surrogate marker of the effects of environmental chemicals on testis descent in human population studies. The rightful place for the testis at birth is in the scrotum in order to provide the temperature differential essential for normal spermatogenesis. Appropriate screening programmes and early surgical intervention are the prerequisites to ensure optimal fertility in adulthood and a considerably lessened risk of testis cancer. PMID:18647820

  11. Fibroblast growth factor 23.

    PubMed

    Smith, Edward R; McMahon, Lawrence P; Holt, Stephen G

    2014-03-01

    There is growing interest in the role of fibroblast growth factor 23 (FGF23) in various diseases of disordered mineral metabolism. In chronic kidney disease (CKD), where biochemical evidence of mineral disturbances is especially common, FGF23 measurement has been advocated as an early and sensitive marker for CKD-related bone disease. In this setting, FGF23 analysis may also improve the discrimination of risk of adverse renal and cardiovascular outcomes and aid targeting of those patients that are likely to benefit from interventions. Nonetheless, while the physiological relevance of FGF23 in the control of mineral metabolism is now firmly established, relatively little attention has been paid to important preanalytical and analytical aspects of FGF23 measurement that may impact on its clinical utility. Here we review these issues and discuss the suitability of FGF23 testing strategies for routine clinical practice. The current 'state-of-the-art' enzyme-linked immunosorbent assay methods for FGF23 measurement show poor agreement due to differences in FGF23 fragment detection, antibody specificity and calibration. Such analytical variability does not permit direct comparison of FGF23 measurements made with different assays and is likely to at least in part account for some of the inconsistencies noted between observational studies. From a clinical perspective, the lack of concordance has implications for the development of standardized reference intervals and clinical decision limits. Finally, the inherent assay-dependent biological variability of plasma FGF23 concentration can further complicate the interpretation of results and the design of FGF23-based testing protocols. Currently, it would be premature to consider incorporating FGF23 measurements into standard testing repertoires. PMID:24269946

  12. Growth factors in ischemic stroke

    PubMed Central

    Lanfranconi, S; Locatelli, F; Corti, S; Candelise, L; Comi, G P; Baron, P L; Strazzer, S; Bresolin, N; Bersano, A

    2011-01-01

    Abstract Data from pre-clinical and clinical studies provide evidence that colony-stimulating factors (CSFs) and other growth factors (GFs) can improve stroke outcome by reducing stroke damage through their anti-apoptotic and anti-inflammatory effects, and by promoting angiogenesis and neurogenesis. This review provides a critical and up-to-date literature review on CSF use in stroke. We searched for experimental and clinical studies on haemopoietic GFs such as granulocyte CSF, erythropoietin, granulocyte-macrophage colony-stimulating factor, stem cell factor (SCF), vascular endothelial GF, stromal cell-derived factor-1? and SCF in ischemic stroke. We also considered studies on insulin-like growth factor-1 and neurotrophins. Despite promising results from animal models, the lack of data in human beings hampers efficacy assessments of GFs on stroke outcome. We provide a comprehensive and critical view of the present knowledge about GFs and stroke, and an overview of ongoing and future prospects. PMID:20015202

  13. Growth factors in synaptic function

    PubMed Central

    Poon, Vivian Y.; Choi, Sojoong; Park, Mikyoung

    2013-01-01

    Synapses are increasingly recognized as key structures that malfunction in disorders like schizophrenia, mental retardation, and neurodegenerative diseases. The importance and complexity of the synapse has fuelled research into the molecular mechanisms underlying synaptogenesis, synaptic transmission, and plasticity. In this regard, neurotrophic factors such as netrin, Wnt, transforming growth factor-? (TGF-?), tumor necrosis factor-? (TNF-?), and others have gained prominence for their ability to regulate synaptic function. Several of these factors were first implicated in neuroprotection, neuronal growth, and axon guidance. However, their roles in synaptic development and function have become increasingly clear, and the downstream signaling pathways employed by these factors have begun to be elucidated. In this review, we will address the role of these factors and their downstream effectors in synaptic function in vivo and in cultured neurons. PMID:24065916

  14. Sigma Factors for Cyanobacterial Transcription

    PubMed Central

    Imamura, Sousuke; Asayama, Munehiko

    2009-01-01

    Cyanobacteria are photosynthesizing microorganisms that can be used as a model for analyzing gene expression. The expression of genes involves transcription and translation. Transcription is performed by the RNA polymerase (RNAP) holoenzyme, comprising a core enzyme and a sigma (?) factor which confers promoter selectivity. The unique structure, expression, and function of cyanobacterial ? factors (and RNAP core subunits) are summarized here based on studies, reported previously. The types of promoter recognized by the ? factors are also discussed with regard to transcriptional regulation. PMID:19838335

  15. Five Describing Factors of Dyslexia.

    PubMed

    Tamboer, Peter; Vorst, Harrie C M; Oort, Frans J

    2014-11-14

    Two subtypes of dyslexia (phonological, visual) have been under debate in various studies. However, the number of symptoms of dyslexia described in the literature exceeds the number of subtypes, and underlying relations remain unclear. We investigated underlying cognitive features of dyslexia with exploratory and confirmatory factor analyses. A sample of 446 students (63 with dyslexia) completed a large test battery and a large questionnaire. Five factors were found in both the test battery and the questionnaire. These 10 factors loaded on 5 latent factors (spelling, phonology, short-term memory, rhyme/confusion, and whole-word processing/complexity), which explained 60% of total variance. Three analyses supported the validity of these factors. A confirmatory factor analysis fit with a solution of five factors (RMSEA = .03). Those with dyslexia differed from those without dyslexia on all factors. A combination of five factors provided reliable predictions of dyslexia and nondyslexia (accuracy >90%). We also looked for factorial deficits on an individual level to construct subtypes of dyslexia, but found varying profiles. We concluded that a multiple cognitive deficit model of dyslexia is supported, whereas the existence of subtypes remains unclear. We discussed the results in relation to advanced compensation strategies of students, measures of intelligence, and various correlations within groups of those with and without dyslexia. PMID:25398549

  16. Growth factors and antimicrobial factors of bovine colostrum

    Microsoft Academic Search

    R. Pakkanen; J. Aalto

    1997-01-01

    Colostrum is the first natural food produced by female mammals during the first 2436h directly after giving birth. Chemically, colostrum is a very complex fluid rich in nutrients, antibodies and growth factors. In cows the antibodies provide passive immunity to the new born calf, whereas the growth factors especially stimulate the growth of the gut. The other antimicrobial components of

  17. Reliability and Validity: One Factor and Third Factor Tests

    E-print Network

    White, Douglas R.

    Chapter 7 Reliability and Validity: One Factor and Third Factor Tests D. White and A. Korotayev 26 Sept 2003 Html links are live Reliability and validity are crucial issues in research. Reliability is concerned with lowered quality of data due to random errors in measurement. Validity is concerned

  18. Women's career success: A factor analytic study of contributing factors

    Microsoft Academic Search

    LuAnn Ricketts Gaskill

    1991-01-01

    Considerable research has been conducted on factors which have enabled men to succeed in management, but only recently has attention been directed toward successful women in management. Researchers interested in identifying factors contributing to women's advancement have done so by focusing on the lives of top women in business and industry (Adams, 1979; Fenn, 1978; Hardesty & Jacobs, 1986; Hennig

  19. Heavy quark impact factor in kT-factorization

    E-print Network

    Grigorios Chachamis; Michal Deak; German Rodrigo

    2013-10-24

    We present the calculation of the finite part of the heavy quark impact factor at next-to-leading logarithmic accuracy in a form suitable for phenomenological studies such as the calculation of the cross-section for single bottom quark production at the LHC within the kT-factorization scheme.

  20. Factorized molecular wave functions: Analysis of the nuclear factor.

    PubMed

    Lefebvre, R

    2015-06-01

    The exact factorization of molecular wave functions leads to nuclear factors which should be nodeless functions. We reconsider the case of vibrational perturbations in a diatomic species, a situation usually treated by combining Born-Oppenheimer products. It was shown [R. Lefebvre, J. Chem. Phys. 142, 074106 (2015)] that it is possible to derive, from the solutions of coupled equations, the form of the factorized function. By increasing artificially the interstate coupling in the usual approach, the adiabatic regime can be reached, whereby the wave function can be reduced to a single product. The nuclear factor of this product is determined by the lowest of the two potentials obtained by diagonalization of the potential matrix. By comparison with the nuclear wave function of the factorized scheme, it is shown that by a simple rectification, an agreement is obtained between the modified nodeless function and that of the adiabatic scheme. PMID:26049477

  1. Factors That Influence Teacher Attrition.

    ERIC Educational Resources Information Center

    Gonzalez, Patricia

    1995-01-01

    External, employment, and personal factors which influence teacher decisions to stay, leave, or transfer from teaching assignments are discussed, with emphasis on special education teachers. Factors attributed to teacher attrition in urban and rural environments also are briefly reviewed, along with attrition of related services professionals.

  2. The kaon electromagnetic form factor

    E-print Network

    J. Lowe; M. D. Scadron

    2005-09-28

    We use recent data on K^+ -> pi^+ e^+ e^-, together with known values for the pion form factor, to derive experimental values for the kaon electromagnetic form factor for 0 < q^2 < 0.125 (GeV/c)^2. The results are then compared with the predictions of the Vector Meson Dominance model, which gives a good fit to the experimental results.

  3. GATA Transcription Factors and Cancer

    Microsoft Academic Search

    Rena Zheng; Gerd A. Blobel

    2010-01-01

    It has been almost a quarter century since it was first appreciated that a class of oncogenes contained in rapidly transforming avian retroviruses encoded DNA-binding transcription factors. As with other oncogenes, genetic recombination with the viral genome led to their overexpression or functional alteration. In the years that followed, alterations of numerous transcription factors were shown to be causatively involved

  4. Escape from the impact factor

    Microsoft Academic Search

    Philip Campbell

    2008-01-01

    As Editor-in-Chief of the journal Nature, I am concerned by the tendency within acade- mic administrations to focus on a journal's impact factor when judging the worth of scientific contri- butions by researchers, affecting promotions, recruitment and, in some countries, financial bonuses for each paper. Our own internal research demonstrates how a high journal impact factor can be the skewed

  5. Statistical Factors in Complexation Reactions.

    ERIC Educational Resources Information Center

    Chung, Chung-Sun

    1985-01-01

    Four cases which illustrate statistical factors in complexation reactions (where two of the reactants are monodentate ligands) are presented. Included are tables showing statistical factors for the reactions of: (1) square-planar complexes; (2) tetrahedral complexes; and (3) octahedral complexes. (JN)

  6. Exogenous Factors in Hair Disorders

    Microsoft Academic Search

    Liran Horev

    2004-01-01

    The health and beauty of human hair have immeasurable psychological importance. Hair structure and its cycle are influenced by intentionally or nonintentionally delivered factors such as grooming, heat styling, chemical agents and climatic exposure. All of these factors are capable of causing loss of hair color and luster, harshness, stiffness, weakness, brittleness and flyaway, transient loss of hair or scarring

  7. Smoking A Renal Risk Factor

    Microsoft Academic Search

    Stephan R. Orth

    2000-01-01

    One of the most important tasks of clinical and experimental nephrology is to identify the risk factors of progression of renal failure. A major renal risk factor which has not been sufficiently acknowledged despite increasing evidence is cigarette smoking. Diabetologists were the first to recognize the adverse effects of smoking on the kidney: both in type 1 and in type

  8. Hormones, growth factors and oncogenes

    SciTech Connect

    Pimentel, E.

    1987-01-01

    This book examines the hormones and peptide growth factors involved in the regulation of metabolism, growth and differentiation in metazoan organisms and proto-oncogene expression. It investigates protein products of some proto-oncogenes for involvement in the transductional and post-transductional and mechanisms of hormones and peptide growth factors.

  9. Exogenous Factors in Atopic Dermatitis

    Microsoft Academic Search

    Emma Guttman-Yassky

    2004-01-01

    The prevalence of atopic dermatitis (AD), the most common inflammatory skin disease in children, has increased over the last decade. Although there is a genetic predisposition to AD, there is strong evidence suggesting a crucial role for environmental factors. The etiology of AD is probably multifactorial and includes interactions between the genetic predisposition and exogenous provocation factors. Many specific exogenous

  10. Investigating Factors that Influence Climate

    NSDL National Science Digital Library

    There are several factors that influence the climate or prevailing weather conditions for any given location on Earth. The most important factor is the latitude of the location because that affects the amount of solar radiation received throughout the year. Other factors include its distance from a body of water (its moisture source), elevation and local topography. In this 6 to 10 day unit plan, students will employ inquiry methods to investigate how latitude and longitude (and distance from oceans) impact climatic factors such as temperature range, average temperature, and precipitation. They will create climatic diagrams called climatograms that allow them to display monthly average weather conditions such as temperature and precipitation at a particular location. They will then use the data to design an investigation about the factors that influence climate.

  11. Magnetically induced phase separation and magnetic properties of Co-Mo hexagonal-close-packed structure thin films

    NASA Astrophysics Data System (ADS)

    Oikawa, K.; Qin, G. W.; Sato, M.; Kitakami, O.; Shimada, Y.; Sato, J.; Fukamichi, K.; Ishida, K.

    2003-08-01

    Magnetically induced phase separation along the Curie temperature in the hexagonal-close-packed phase of a Co-Mo binary system has been predicted by thermodynamic calculations. Furthermore, the phase separation and magnetic properties of Co-Mo sputtered thin films have been investigated. Nanoscale compositional fluctuation caused by the magnetically induced phase separation has been confirmed in the films deposited on a heated substrate in the same manner as Co-Cr-based alloys. The magnetic anisotropy constant of the Co-Mo films is larger than that of Co-Cr films. From these results, it is concluded that the Co-Mo system is promising for use as a base alloy system for high density recording media.

  12. Characterization and Hydrodesulfurization Activity of CoMo Catalysts Supported on Boron-Doped Sol-Gel Alumina

    E-print Network

    Boyer, Edmond

    desulfurization character of the CoMo catalysts supported on the B- Al2O3 supports, because high hydrogenation of sulfur tolerated in gasoline in the US has been decreased to 15 ppm [2], and that in all

  13. Development of stress intensification factors

    SciTech Connect

    Minichiello, J.C. [VECTRA Technologies, Inc., Naperville, IL (United States); Rodabaugh, E.C.

    1995-12-01

    B31.1 Equation 13A, B31.3 Equation 18, and Section 3 Paragraphs NC/ND-3653 EQS. (10), (10a), and 11 all use i-factors (SIFs) to compute stresses in piping due to displacement induced loadings. Appendix D of the B31 Standards and Figure NC/ND-3673.2(b)-1 of Section 3 give values of i-factors for commonly used piping components. A need occasionally arises to establish i-factors for other components (e.g., a branch connection in an elbow). In order to provide guidance on the development of these factors, a new draft Appendix has been prepared to assure that the experimental procedures and interpretation of the test results leading to new i-factors are consistent with the basis for existing i-factors. This paper discusses the background to the proposed Appendix, using the Section 3 version as a model, and also provides the authors` opinions an the need for experimental verification (vs purely analytical computation) of i-factors. The Appendix proposed is to be part of Appendix 2 of Section 3.

  14. Factorization in exclusive quarkonium production

    SciTech Connect

    Bodwin, Geoffrey T.; Garcia i Tormo, Xavier; Lee, Jungil [High Energy Physics Division, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); High Energy Physics Division, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439, USA and Department of Physics, University of Alberta, Edmonton, Alberta, T6G 2G7 (Canada); Department of Physics, Korea University, Seoul 136-701 (Korea, Republic of)

    2010-06-01

    We present factorization theorems for two exclusive heavy-quarkonium production processes: production of two quarkonia in e{sup +}e{sup -} annihilation and production of a quarkonium and a light meson in B-meson decays. We describe the general proofs of factorization and supplement them with explicit one-loop analyses, which illustrate some of the features of the soft-gluon cancellations. We find that violations of factorization are generally suppressed relative to the factorized contributions by a factor v{sup 2}m{sub c}/Q for each S-wave charmonium and a factor m{sub c}/Q for each L-wave charmonium with L>0. Here, v is the velocity of the heavy quark or antiquark in the quarkonium rest frame, Q={radical}(s) for e{sup +}e{sup -} annihilation, Q=m{sub B} for B-meson decays, {radical}(s) is the e{sup +}e{sup -} center-of-momentum energy, m{sub c} is the charm-quark mass, and m{sub B} is the B-meson mass. There are modifications to the suppression factors if quantum-number restrictions apply for the specific process.

  15. Factorization in exclusive quarkonium production.

    SciTech Connect

    Bodwin, G. T.; Garcia i Tormo, X.; Lee, J.; High Energy Physics; Korea Univ.; Korea Inst. of Science and Technology Information; Univ. of Alberta

    2010-01-01

    We present factorization theorems for two exclusive heavy-quarkonium production processes: production of two quarkonia in e{sup +}e{sup -} annihilation and production of a quarkonium and a light meson in B-meson decays. We describe the general proofs of factorization and supplement them with explicit one-loop analyses, which illustrate some of the features of the soft-gluon cancellations. We find that violations of factorization are generally suppressed relative to the factorized contributions by a factor v{sup 2}m{sub c}/Q for each S-wave charmonium and a factor m{sub c}/Q for each L-wave charmonium with L > 0. Here, v is the velocity of the heavy quark or antiquark in the quarkonium rest frame, Q = {radical}s for e{sup +}e{sup -} annihilation, Q = m{sub B} for B-meson decays, {radical}s is the e{sup +}e{sup -} center-of-momentum energy, m{sub c} is the charm-quark mass, and m{sub B} is the B-meson mass. There are modifications to the suppression factors if quantum-number restrictions apply for the specific process.

  16. GATA Transcription Factors and Cancer.

    PubMed

    Zheng, Rena; Blobel, Gerd A

    2010-12-01

    It has been almost a quarter century since it was first appreciated that a class of oncogenes contained in rapidly transforming avian retroviruses encoded DNA-binding transcription factors. As with other oncogenes, genetic recombination with the viral genome led to their overexpression or functional alteration. In the years that followed, alterations of numerous transcription factors were shown to be causatively involved in various cancers in human patients and model organisms. Depending on their normal cellular functions, these factors were subsequently categorized as proto-oncogenes or tumor suppressor genes. This review focuses on the role of GATA transcription factors in carcinogenesis. GATA factors are zinc finger DNA binding proteins that control the development of diverse tissues by activating or repressing transcription. GATA factors thus coordinate cellular maturation with proliferation arrest and cell survival. Therefore, a role of this family of genes in human cancers is not surprising. Prominent examples include structural mutations in GATA1 that are found in almost all megakaryoblastic leukemias in patients with Down syndrome; loss of GATA3 expression in aggressive, dedifferentiated breast cancers; and silencing of GATA4 and GATA5 expression in colorectal and lung cancers. Here, we discuss possible mechanisms of carcinogenesis vis--vis the normal functions of GATA factors as they pertain to human patients and mouse models of cancer. PMID:21779441

  17. Factors Affecting Medical Service Quality

    PubMed Central

    MOSADEGHRAD, Ali Mohammad

    2014-01-01

    Abstract Background A better understanding of factors influencing quality of medical service can pinpoint better strategies for quality assurance in medical services. This study aimed to identify factors affecting the quality of medical services provided by Iranian physicians. Methods Exploratory in-depth individual interviews were conducted with sixty-four physicians working in various medical institutions in Iran. Results Individual, organizational and environmental factors enhance or inhibit the quality of medical services. Quality of medical services depends on the personal factors of the physician and patient, and factors pertaining to the healthcare setting and the broader environment. Conclusion Differences in internal and external factors such as availability of resources, patient cooperation and collaboration among providers affect the quality of medical services and patient outcomes. Supportive leadership, proper planning, education and training and effective management of resources and processes improve the quality of medical services. This article contributes to healthcare theory and practice by developing a conceptual framework for understanding factors that influence medical services quality.

  18. Factors Affecting Option Premium Values

    E-print Network

    Johnson, Jason; Smith, Jackie; Dhuyvetter, Kevin C.; Waller, Mark L.

    1999-06-23

    Factors Affecting Option Premium Values Jason Johnson, Jackie Smith, Kevin Dhuyvetter and Mark Waller* Put Options Hedging in the futures market with options is much like buying an insurance policy to protect commodity sellers against declining...

  19. Automatic Test Factoring for Java

    E-print Network

    Saff, David

    2005-06-08

    Test factoring creates fast, focused unit tests from slow system-widetests; each new unit test exercises only a subset of the functionalityexercised by the system test. Augmenting a test suite with factoredunit tests ...

  20. Chemical Specific Adjustment factors Workshop

    EPA Science Inventory

    The World Health Organization, through the International Programme on Chemical Safety (IPCS), has established guidance on the use of mechanistic data to replace default uncertainty factors for interspecies extrapolation and intraspecies variability in deriving risk values such as...

  1. What Factors Impact a Greenhouse?

    NSDL National Science Digital Library

    This activity has students use a model to investigate factors in greenhouse heating and cooling. The type of surface that sunlight first encounters is the most important factor. Forests, grasslands, ocean surfaces, ice caps, deserts, and cities all absorb, reflect, and radiate radiation differently. As a result of this activity students will be able to identify at least three factors affecting the heat-trapping ability of a greenhouse, explain the factors important in the atmosphere's heat trapping ability, and understand the influence of albedo on earth's temperature. The student guide has an overall description of the activity, a list of materials, the procedure, and observations and questions. The instructor guide contains detailed background material, learning goals, alignment to national standards, grade level/time, details on materials and preparation, procedure, assessment ideas, and modifications for alternative learners.

  2. Risk factors for equine laminitis

    E-print Network

    Polzer, John Patrick

    1995-01-01

    logistic regression to assess age, breed, sex, and seasonality as risk factors for equine laminitis. There were 70 acute cases, 183 chronic cases, and 779 controls. No statistical association was found between age, breed, sex, or seasonality...

  3. Risk factors for equine laminitis

    E-print Network

    Polzer, John Patrick

    1995-01-01

    : Epidemiology RISK FACTORS FOR EQUINE LAMINITIS A Thesis by JOHN PATRICK POLZER Submitted to Texas A8cM University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved as to style and content by: Margaret Slater... (Chair of Co i ee) James Calvin (Me be Stuart Shalat (Member) Gerald Bratton (Head of Department) December 1995 Major Subject: Epidemiology ABSTRACT Risk Factors for Equine Laminitis. (December 1995) John Patrick Polzer, B. S. , St. Norbert...

  4. Neighborhood Risk Factors for Obesity

    Microsoft Academic Search

    Russ P. Lopez

    2007-01-01

    Objective: The goal of this study was to explore neighborhood environmental factors associated with obesity in a sample of adults living in a major U.S. metropolitan area.Research Methods and Procedures: This was a multi-level study combining data from the U.S. Behavioral Risk Factor Surveillance System with data from the U.S. Census. A total of 15,358 subjects living in 327 zip

  5. Screening and Risk Factors Table

    Cancer.gov

    Shows data at the state level related to a number of screening and risk factors associated with cancer in terms of percent and the sample survey size. The data for this table is from the Behavioral Risk Factors Surveillance System Summary Prevalence Report and is compared to the Healthy People 2020 target values. You can sort the data on the table by State name and percent value.

  6. Growth Factors and Neuropathic Pain

    Microsoft Academic Search

    Michael H. Ossipov

    2011-01-01

    A treatment for neuropathic pain is an important unmet medical need because this pain often is refractory to many medical\\u000a interventions. An important element in the development of neuropathic pain is a dysfunction in the activity of peripheral\\u000a nerves. Because neurotrophic factors affect nerve development and maintenance, modulating the activity of these factors can\\u000a alter neuronal pathophysiology and produce a

  7. Industrial Power Factor Analysis Guidebook.

    SciTech Connect

    Electrotek Concepts.

    1995-03-01

    Power factor is a way of measuring the percentage of reactive power in an electrical system. Reactive power represents wasted energy--electricity that does no useful work because the electrical current is out of phase with the voltage. Reactive power is used by inductive loads (such as, motors, transformers, fluorescent lights, arc welders and induction furnaces) to sustain their magnetic fields. Electric systems with many motors exhibit low power factors, increased conductor and transformer losses, and lower voltages. Utilities must supply both active and reactive power and compensate for these losses. Power factor can be improved by the addition of shunt capacitors. Capacitors act in opposition to inductive loads, thereby minimizing the reactive power required to serve them. In raising the power factor, shunt capacitors release energy to the system, reduce system losses, and ultimately decrease power costs. Improving system power factor can reduce reactive and active power losses for both industry and utilities through the addition of shunt capacitors. This Guide Book gives electric utility technical staff, industrial end-users, consultants and BPA employees a step-by-step method for evaluating the cost effectiveness of installing power factor correction capacitors in an industrial plant.

  8. Sparse Bayesian infinite factor models

    PubMed Central

    Bhattacharya, A.; Dunson, D. B.

    2011-01-01

    We focus on sparse modelling of high-dimensional covariance matrices using Bayesian latent factor models. We propose a multiplicative gamma process shrinkage prior on the factor loadings which allows introduction of infinitely many factors, with the loadings increasingly shrunk towards zero as the column index increases. We use our prior on a parameter-expanded loading matrix to avoid the order dependence typical in factor analysis models and develop an efficient Gibbs sampler that scales well as data dimensionality increases. The gain in efficiency is achieved by the joint conjugacy property of the proposed prior, which allows block updating of the loadings matrix. We propose an adaptive Gibbs sampler for automatically truncating the infinite loading matrix through selection of the number of important factors. Theoretical results are provided on the support of the prior and truncation approximation bounds. A fast algorithm is proposed to produce approximate Bayes estimates. Latent factor regression methods are developed for prediction and variable selection in applications with high-dimensional correlated predictors. Operating characteristics are assessed through simulation studies, and the approach is applied to predict survival times from gene expression data. PMID:23049129

  9. Tissue factor and factor VIIa Hemostasis and Beyond

    PubMed Central

    Wolberg, Alisa S.; Mast, Alan E.

    2012-01-01

    Initiation of the coagulation cascade via exposure of active tissue factor (TF) to blood and formation of the factor VIIa/TF complex is essential for hemostasis and is an initial procoagulant signal in thrombosis. As of early 2012, over 20,000 articles listed on PubMed describe advances in the understanding of TF biology in the settings of hemostasis and thrombosis, as well as in signaling events in cancer, sickle cell anemia, hyperlipidemia, and a broad spectrum of inflammatory disorders. It is both inspiring and humbling, then, to consider not only what has been learned about TF regulation, but also the number of questions still remaining about its role in physiology. This supplement reviews both well-accepted and currently-controversial topics in coagulation and factor VIIa/TF biology, with particular foci on non-hemostatic roles of TF, innovative approaches for the treatment of hemophilia, and novel in vivo models of bleeding and thrombosis. PMID:22417944

  10. Selective inhibition of factor inhibiting hypoxia-inducible factor.

    PubMed

    McDonough, Michael A; McNeill, Luke A; Tilliet, Melanie; Papamical, Cyril A; Chen, Qiu-Yun; Banerji, Biswadip; Hewitson, Kirsty S; Schofield, Christopher J

    2005-06-01

    A set of four non-heme iron(II) and 2-oxoglutarate-dependent enzymes catalyze the post-translational modification of a transcription factor, hypoxia inducible factor (HIF), that mediates the hypoxic response in animals. Hydroxylation of HIF both causes its degradation and limits its activity. We describe how the use of structural data coupled to solid-phase synthesis led to the discovery of a selective inhibitor of one of the HIF hydroxylases. The inhibitor N-oxalyl-d-phenylalanine was shown to inhibit the HIF asparaginyl hydroxylase (FIH) but not a HIF prolyl hydroxylase. A crystal structure of the inhibitor complexed to FIH reveals that it binds in the 2OG and, likely, in the dioxygen binding site. The results will help to enable the modulation of the hypoxic response for the up-regulation of specific genes of biomedical importance, such as erythropoietin and vascular endothelial growth factor. PMID:15913349

  11. Factorization for generic jet production

    SciTech Connect

    Bauer, Christian W.; Hornig, Andrew; Tackmann, Frank J. [Ernest Orlando Lawrence Berkeley National Laboratory, University of California, Berkeley, California 94720 (United States)

    2009-06-01

    Factorization is the central ingredient in any theoretical prediction for collider experiments. We introduce a factorization formalism that can be applied to any desired observable, like event shapes or jet observables, for any number of jets and a wide range of jet algorithms in leptonic or hadronic collisions. This is achieved by using soft-collinear effective theory to prove the formal factorization of a generic fully differential cross section in terms of a hard coefficient, and generic jet and soft functions. In this formalism, whether a given observable factorizes in the usual sense, depends on whether it is inclusive enough, so the jet functions can be calculated perturbatively. The factorization formula for any such observable immediately follows from our general result, including the precise definition of the jet and soft functions appropriate for the observable in question. As examples of our formalism, we work out several results in two-jet production for both e{sup +}e{sup -} and pp collisions. For the latter, we also comment on how our formalism allows one to treat underlying events and beam remnants.

  12. Vascular growth factors in neuropsychiatry

    PubMed Central

    Newton, Samuel S.; Fournier, Neil M.; Duman, Ronald S.

    2014-01-01

    Recent advances in understanding the cellular and molecular basis of psychiatric illnesses have shed light on the important role played by trophic factors in modulating functional parameters associated with disease causality and drug action. Disease mechanisms are now thought to involve multiple cell types, including neurons and endothelial cells. These functionally distinct but interactively coupled cell types engage in cellular cross talk via shared and common signaling molecules. Dysregulation in their cellular signaling pathways influences brain function and alters behavioral performance. Multifunctional trophic factors such as VEGF and EPO that possess both neurotrophic and angiogenic actions are of particular interest due to their ability to rescue structural and plasticity deficits in neurons and vasculature. Obtaining insight into the behavioral, cellular and molecular actions of multi-functional trophic factors has the potential to open new and transformative therapeutic approaches. PMID:23475069

  13. Dnmt1/Transcription Factor Interactions

    PubMed Central

    Hervouet, Eric; Vallette, Franois M.; Cartron, Pierre-Franois

    2010-01-01

    DNA methylation inheritance is the process of copying, via the DNA methyltransferase 1 (Dnmt1), the pre-existing methylation patterns onto the new DNA strand during DNA replication. Experiments of chromatin immunoprecipitation, measurement of maintenance methyltransferase activity, proximity ligation in situ assays (P-LISA, Duolink/Olink), and transcription factor arrays demonstrate that Dnmt1 interacts with transcription factors to promote site-specific DNA methylation inheritance, while the Dnmt1-PCNA-UHRF1 complex promotes the DNA methylation inheritance without site preference. We also show that the Dnmt1-PCNA-UHRF1 and Dnmt1/transcription factor complexes methylate DNA by acting as a single player or in cooperation. Thus, our data establish that the copying of the pre-existing methylation pattern is governed by the orchestration of the untargeted and the targeted mechanisms of DNA methylation inheritance, which are themselves dictated by the partners of Dnmt1. PMID:21779454

  14. Isospectral potentials from modified factorization

    SciTech Connect

    Berger, Micheal S.; Ussembayev, Nail S. [Department of Physics, Indiana University, Bloomington, Indiana 47405 (United States)

    2010-08-15

    Factorization of quantum-mechanical potentials has a long history extending back to the earliest days of the subject. In the present article, the nonuniqueness of the factorization is exploited to derive new isospectral nonsingular potentials. Many one-parameter families of potentials can be generated from known potentials using a factorization that involves superpotentials defined in terms of excited states of a potential. For these cases an operator representation is available. If ladder operators are known for the original potential, then a straightforward procedure exists for defining such operators for its isospectral partners. The generality of the method is illustrated with a number of examples which may have many possible applications in atomic and molecular physics.

  15. [Heliogeophysical factors and aviation accidents].

    PubMed

    Komarov, F I; Oraevski?, V N; Sizov, Iu P; Tsirul'nik, L B; Kanonidi, Kh D; Ushakov, I B; Shalimov, P M; Kimlyk, M V; Glukhov, D V

    1998-01-01

    It was shown by two independent methods that there is a certain correlation between the number of aviation accidents and heliogeophysical factors. The statistical and spectral analyses of time series of heliogeomagnetic factors and the number of aviation accidents in 1989-1995 showed that, of 216 accidents, 58% are related to sudden geomagnetic storms. A similar relation was revealed for aviation catastrophes (64% out of 86 accidents) and emergencies (54% out of 130 accidents) that coincided in time with heliogeomagnetic storms. General periodicities of the series were revealed by the method of spectral analysis, namely, cycles of 30, 42, 46, 64, 74, 83, 99, 115, 143, 169, 339 days, which confirms the causative relation between the number of aviation accidents and heliogeomagnetic factors. It is assumed that some aviation accidents that coincided in time with geomagnetic storms, are due to changes in professional abilities of pilots that were in the zone of storms. PMID:9783079

  16. Environmental risk factors for osteoporosis

    SciTech Connect

    Goyer, R.A.; Korach, K.S. (National Institute of Environmental Health Sciences, Triangle Park, NC (United States)); Epstein, S. (Albert Einstein Medical Center, Philadelphia, PA (United States)); Bhattacharyya, M. (Argonne National Lab., IL (United States)); Pounds, J. (Wayne State Univ., Detroit, MI (United States))

    1994-04-01

    Environmental risk factors for osteoporosis were reviewed at a conference held at the National Institute for Environmental Health Sciences 8-9 November 1993. The conference was co-sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Disease and the NIH Office of Research in Women's Health. The objective of the conference was to review what is known about risk factors for osteoporosis and to identify gaps in the present state of knowledge that might be addressed by future research. The conference was divided into two broad themes. The first session focused on current knowledge regarding etiology, risk factors, and approaches to clinical and laboratory diagnosis. This was followed by three sessions in which various environmental pollutants were discussed. Topics selected for review included environmental agents that interfere with bone and calcium metabolism, such as the toxic metals lead, cadmium, aluminum, and fluoride, natural and antiestrogens, calcium, and vitamin D.

  17. The Generalized Dynamic Factor Model determining the number of factors

    Microsoft Academic Search

    Marc Hallin; Roman Liska

    This paper develops an information criterion for the choice of the number of common shocks for the approximate dynamic factor model developed by Forni, Hallin, Lippi, and Reichlin (2000). In this framework, the number q of common shocks is associated to the number of diverging eigenvalues of the spectral density matrix of the observations as the number n of time

  18. Kl3 Form Factors and the Pion Charge Form Factor

    Microsoft Academic Search

    H. T. Nieh

    1966-01-01

    Phenomenological Lagrangian models for Kl3 decays and the pion charge form factor are introduced by assuming single-particle dominance and the trilinear meson interactions derived by Schwinger from his composite model for mesons. The usual pole models in the dispersion approach assume that the structure of a \\

  19. Pion Form Factor in the $k_T$ Factorization Formalism

    E-print Network

    T. Huang; X. G. Wu; X. H. Wu

    2004-06-12

    Based on the light-cone (LC) framework and the $k_T$ factorization formalism, the transverse momentum effects and the different helicity components' contributions to the pion form factor $F_{\\pi}(Q^2)$ are recalculated. In particular, the contribution to the pion form factor from the higher helicity components ($\\lambda_1+\\lambda_2=\\pm 1$), which come from the spin-space Wigner rotation, are analyzed in the soft and hard energy regions respectively. Our results show that the right power behavior of the hard contribution from the higher helicity components can only be obtained by fully keeping the $k_T$ dependence in the hard amplitude, and that the $k_T$ dependence in LC wave function affects the hard and soft contributions substantially. As an example, we employ a model LC wave function to calculate the pion form factor and then compare the numerical predictions with the experimental data. It is shown that the soft contribution is less important at the intermediate energy region.

  20. Derived Basic Ability Factors: A Factor Analysis Replication Study.

    ERIC Educational Resources Information Center

    Lee, Mickey, M.; Lee, Lynda Newby

    The purpose of this study was to replicate the study conducted by Potter, Sagraves, and McDonald to determine whether their recommended analysis could separate criterion variables into similar factors that were stable from year to year and from school to school. The replication samples consisted of all students attending Louisiana State University

  1. Bayes factors and multimodel inference

    USGS Publications Warehouse

    Link, W.A.; Barker, R.J.

    2009-01-01

    Multimodel inference has two main themes: model selection, and model averaging. Model averaging is a means of making inference conditional on a model set, rather than on a selected model, allowing formal recognition of the uncertainty associated with model choice. The Bayesian paradigm provides a natural framework for model averaging, and provides a context for evaluation of the commonly used AIC weights. We review Bayesian multimodel inference, noting the importance of Bayes factors. Noting the sensitivity of Bayes factors to the choice of priors on parameters, we define and propose nonpreferential priors as offering a reasonable standard for objective multimodel inference.

  2. Nucleon Form Factors at JLab

    NASA Astrophysics Data System (ADS)

    Jones, Mark

    2001-10-01

    At Jefferson Lab, the measurement of the nucleon electromagnetic form factors has been a major focus of the experimental program. The electron beam at Jefferson Lab is available with high current ( ~ 100 ?A) and high polarization ( ~ 80%). With this quality beam, experiments have pushed the precision of the measurements and increased the range of Q^2, the four-momentum transferred squared. A variety of experimental techniques have been used to obtain the nucleon electro-magnetic form factors at Jefferson Lab including the use of polarized targets and recoil polarization. An overview will be given of the various experiments.

  3. Radiant-interchange configuration factors

    E-print Network

    Reddin, Thomas Edward

    1965-01-01

    between two detached rectangles (see surfaces A and D, Figure 2, 6) having one common dimension and included angle e. This means that the value FAD or FDA is needed. It is well known that and where and 1D 12 1C FDI FDA + FDB AD 1D T Dl 1 Al area... and 8 a b FAD ~ [F12-F1C] - ~ [F82-FBC] (2. 33) Now, by using equation 2. 22 to find the configuration factors F12' F1C' F82 and FBC' the configuration factor FAD can be obtained. CHAPTER III METHODS OF SOLUTION Exact integration of equation 2...

  4. Thermal factors--indoor climate.

    PubMed

    Espejord, I

    2000-10-01

    From 1950 and until today, building technology has developed continuously, especially concerning insulation and sealing (2). Therefore the Norwegian houses of today resist cold and wind very well. But there are still factors that can provide thermal discomfort. Some of these factors can for instance be open indoor solutions, placement and number of windows and sources of heat, upgrading and maintenance of old houses. Important thermal parameters are draught and air velocity, vertical air temperature differences, asymmetry of thermal radiation, floor temperature and relative humidity (4). PMID:11209674

  5. Environmental factors associated with asthma.

    PubMed Central

    Walker, Bailus; Stokes, Lynette D.; Warren, Rueben

    2003-01-01

    Asthma, a disease of attacks and remission, continues to account for substantial morbidity and direct economic costs. Numerous studies--epidemiologic, toxicologic and clinical--present evidence for a broad spectrum of environmental risk factors associated with asthma. This review summarizes current thinking on a subset of these factors. Knowledge of potential environmental determinants of asthma is important to both the patient and healthcare professional in the application of multiple modalities of medical and environmental intervention for management of the development, and exacerbation of this chronic inflammatory disorder of the airways. PMID:12760611

  6. Factor Structure of the Rational Behavior Inventory.

    ERIC Educational Resources Information Center

    Himle, David P.; And Others

    1985-01-01

    Administered the Rational Behavior Inventory (RBI) to 510 undergraduates and performed factor analytic procedures. Comparison with the original factors showed nine of the original 11 factor patterns were approximated reasonably. (JAC)

  7. Genetics Home Reference: Complement factor I deficiency

    MedlinePLUS

    ... PubMed Recent literature OMIM Genetic disorder catalog Conditions > Complement factor I deficiency On this page: Description Genetic ... names Glossary definitions Reviewed September 2010 What is complement factor I deficiency? Complement factor I deficiency is ...

  8. Genetics Home Reference: Factor X deficiency

    MedlinePLUS

    ... Recent literature OMIM Genetic disorder catalog Conditions > Factor X deficiency On this page: Description Genetic changes Inheritance ... Glossary definitions Reviewed January 2015 What is factor X deficiency? Factor X deficiency is a rare bleeding ...

  9. 40 CFR 1033.245 - Deterioration factors.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Determine deterioration factors as described in this...with an engineering analysis, with pre-existing...base the deterioration factor. (2) If you determine your deterioration factors based on engineering analysis, explain why...

  10. 40 CFR 1042.245 - Deterioration factors.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...deterioration factors for Category...an engineering analysis, with pre-existing...deterioration factors for an engine...on engineering analysis instead of testing...deterioration factors based on engineering analysis, explain...

  11. 40 CFR 1033.245 - Deterioration factors.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Determine deterioration factors as described in this...with an engineering analysis, with pre-existing...base the deterioration factor. (2) If you determine your deterioration factors based on engineering analysis, explain why...

  12. 40 CFR 1042.245 - Deterioration factors.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...deterioration factors for Category...an engineering analysis, with pre-existing...deterioration factors for an engine...on engineering analysis instead of testing...deterioration factors based on engineering analysis, explain...

  13. Chloramphenicol Acetyltransferases Specified by fi? R Factors

    PubMed Central

    Foster, T. J.; Shaw, W. V.

    1973-01-01

    Chloramphenicol acetyltransferases specified by fi? (F fertility-noninhibiting) R factors were compared with those specified by the fi+ R factors R1, 222, and R6-S. Three classes of enzyme were distinguished: class I was determined by group N fi? R factors and was indistinguishable from the enzyme determined by fi+ R factors, class II was correlated with group W fi? R factors, and class III was determined by R387, an unclassified fi? R factor. Images PMID:4597710

  14. Hidden Risk Factors for Women

    MedlinePLUS

    ... previous history of clots in the legs (deep vein thrombosis) and livedo reticularis, a mottled purplish discoloration of the skin. Risk factors are cumulative, Dr. Kittner adds. Reducing even one risk can greatly lower your ... 7 What You Should Know About Cerebral Aneurysms 8 Learn More Stroke Warning Signs and ...

  15. Text Mining Nonnegative Matrix Factorization

    E-print Network

    Kunkle, Tom

    Text Mining using the Nonnegative Matrix Factorization Amy Langville Carl Meyer Department: Guide D3: Child Safety at Home T4: Health D4: Your Baby's Health & Safety : From Infant to Toddler T5 Babies Collector's Guide T8: Safety T9: Toddler #12;Example from Berry's book Terms Documents T1: Bab

  16. QR factorization of Toeplitz matrices

    Microsoft Academic Search

    A. W. Bojanczyk; R. P. Brent; F. R. de Hoog

    1986-01-01

    Summary This paper presents a new algorithm for computing theQR factorization of anmn Toeplitz matrix inO(mn) operations. The algorithm exploits the procedure for the rank-1 modification and the fact that both principal (m-1)(n-1) submatrices of the Toeplitz matrix are identical. An efficient parallel implementation of the algorithm is possible.

  17. On Techniques of Prime Factorization

    ERIC Educational Resources Information Center

    Cohen, David B.

    1977-01-01

    This article gives two methods of resolving natural numbers into prime factors. Depending upon the number that is being resolved, one method may be better to use than the other. However, it is difficult to tell beforehand which is the better method to employ. Examples are given. (Author/MA)

  18. Wave Packets can Factorize Numbers

    E-print Network

    Holger Mack; Marc Bienert; Florian Haug; Matthias Freyberger; Wolfgang P. Schleich

    2002-08-30

    We draw attention to various aspects of number theory emerging in the time evolution of elementary quantum systems with quadratic phases. Such model systems can be realized in actual experiments. Our analysis paves the way to a new, promising and effective method to factorize numbers.

  19. On the number of factors

    Microsoft Academic Search

    Quinn McNemar

    1942-01-01

    A proposed criterion for the number of factors is developed on the basis of the similarity between a factorial residual and the partial correlation coefficient; something is known concerning the sampling error of the latter. Instead of computing the residuals as partials, a formula is presented for adjusting the standard deviation of the distribution of residuals so as to approximate

  20. Factors Affecting Onset of Puberty

    Microsoft Academic Search

    Henriette A. Delemarre-van de Waal; Silvia C. C. M. van Coeverden; Mia J. T. Engelbregt

    2002-01-01

    In humans, foetal and early postnatal growth failure may have persistent consequences for growth and pubertal development in later life. During this period, the developing organs are still plastic to change their function, which may have long-lasting effects. At the time of onset of puberty, acute factors may also interfere with pubertal development. Malnutrition, as seen in anorexic patients, and

  1. Human Factors in Electrical Safety

    Microsoft Academic Search

    S. Jamil; A. Golding; H. L. Floyd; M. Capelli-Schellpfeffer

    2007-01-01

    Compliance with regulations or consensus codes and standards is often not sufficient to eliminate the potential for injury or fatality from electrical sources. Recently available data on the scope of electrical incidents underscores the need to revisit the strategic advantages to be gained through implementation of human factors principles across engineering and management processes. This review provides historical, regulatory, and

  2. Critical factors to bioenergy implementation

    Microsoft Academic Search

    Anders Roos; Robin L. Graham; Bo Hektor; Christian Rakos

    1999-01-01

    Barriers to bioenergy technology implementation have received increased attention in recent years. This paper contributes to the identification and analysis of barriers and drivers behind bioenergy market growth, here labelled critical factors. It presents a framework for the analysis of both existing and projected bioenergy market potential, using economic concepts and models from transaction cost theory and industrial organization. The

  3. Factor reliability into load management

    SciTech Connect

    Feight, G.R.

    1983-07-01

    Hardware reliability is a major factor to consider when selecting a direct-load-control system. The author outlines a method of estimating present-value costs associated with system reliability. He points out that small differences in receiver reliability make a significant difference in owning cost. 4 figures.

  4. Factors Affecting Willingness to Mentor

    ERIC Educational Resources Information Center

    Ghislieri, Chiara; Gatti, Paola; Quaglino, Gian Piero

    2009-01-01

    The paper presents a survey among 300 employees in Northern Italy to assess the willingness to mentor and identify the factors that affect it. Men and respondents with previous mentoring experience indicate a higher willingness to be a mentor. Willingness is affected by personal characteristics that are perceived as necessary for a mentor and the

  5. Timing vulnerability factors of sequentials

    Microsoft Academic Search

    Norbert Seifert; Nelson Tam

    2004-01-01

    Single-event upsets (SEU) from particle strikes have become a key challenge in microprocessor design. Modern superpipelined microprocessors typically contain many thousands of sequentials whose soft-error rate (SER) cannot be neglected any more. An accurate assessment of the SER of sequentials is therefore crucial. This work describes a method for computing timing vulnerability factors (TVFs) of sequentials. Our methology captures the

  6. Clotting factors after emergency contraception

    Microsoft Academic Search

    A. Webb; D. Taberner

    1993-01-01

    Women with a previous history of thromboembolic disease have often been denied oral emergency contraception because of a theoretical concern about increasing their risk of thrombosis. Methods Eleven healthy volunteers with regular periods were recruited to the study. A thrombophilia screen was done at the first visit and they each had four measurements of Factor VII and antithrombin III taken

  7. NASA Space Human Factors Program

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This booklet briefly and succinctly treats 23 topics of particular interest to the NASA Space Human Factors Program. Most articles are by different authors who are mainly NASA Johnson or NASA Ames personnel. Representative topics covered include mental workload and performance in space, light effects on Circadian rhythms, human sleep, human reasoning, microgravity effects and automation and crew performance.

  8. Factors Determining Work-load

    Microsoft Academic Search

    JACQUES LEPLAT

    1978-01-01

    In this short introduction to the topic of the symposium, some analytical elements are suggested for the concept of work-load, the large variety or work-load categories is recalled, and mention is made of some factors determining work-load, which will be elaborated on in the papers presented by other authors.

  9. Factors affecting supplier quality performance

    Microsoft Academic Search

    L. B. Forker

    1997-01-01

    The interest among practitioners and researchers in quality management and other factors that may affect quality performance reflects the understanding that a firm's output (i.e., performance) can be only as good as the quality of its inputs. However, studies of the quality management-quality performance relationship have led to mixed results regarding the existence of a positive correlation between the two.

  10. Factors Affecting Illegal Hacking Behavior

    Microsoft Academic Search

    Randall Young; Lingling Zhang

    2005-01-01

    The damage caused by illegal hacking has become one of the serious problems facing society. Based on general deterrence theory, social bond theory and social learning theory, the paper proposes a model which examines the factors affecting the likelihood an individual will engage in illegal hacking behavior. Data was gathered from a survey of 127 individuals who attended a hackers

  11. Efficient networks for quantum factoring

    SciTech Connect

    Beckman, D.; Chari, A.N.; Devabhaktuni, S.; Preskill, J. [California Institute of Technology, Pasadena, California 91125 (United States)] [California Institute of Technology, Pasadena, California 91125 (United States)

    1996-08-01

    We consider how to optimize memory use and computation time in operating a quantum computer. In particular, we estimate the number of memory quantum bits (qubits) and the number of operations required to perform factorization, using the algorithm suggested by Shor [in {ital Proceedings} {ital of} {ital the} 35{ital th} {ital Annual} {ital Symposium} {ital on} {ital Foundations} {ital of} {ital Computer} {ital Science}, edited by S. Goldwasser (IEEE Computer Society, Los Alamitos, CA, 1994), p. 124]. A {ital K}-bit number can be factored in time of order {ital K}{sup 3} using a machine capable of storing 5{ital K}+1 qubits. Evaluation of the modular exponential function (the bottleneck of Shor{close_quote}s algorithm) could be achieved with about 72{ital K}{sup 3} elementary quantum gates; implementation using a linear ion trap would require about 396{ital K}{sup 3} laser pulses. A proof-of-principle demonstration of quantum factoring (factorization of 15) could be performed with only 6 trapped ions and 38 laser pulses. Though the ion trap may never be a useful computer, it will be a powerful device for exploring experimentally the properties of entangled quantum states. {copyright} {ital 1996 The American Physical Society.}

  12. Human factors in software development

    SciTech Connect

    Curtis, B.

    1986-01-01

    This book presents an overview of ergonomics/human factors in software development, recent research, and classic papers. Articles are drawn from the following areas of psychological research on programming: cognitive ergonomics, cognitive psychology, and psycholinguistics. Topics examined include: theoretical models of how programmers solve technical problems, the characteristics of programming languages, specification formats in behavioral research and psychological aspects of fault diagnosis.

  13. Pollution, Factor Taxation and Unemployment

    Microsoft Academic Search

    Erkki Koskela; Ronnie Schb; Hans-Werner Sinn

    1998-01-01

    When consumers choose between clean and dirty goods and the labour market clears, a green tax reform may not bring about a double dividend in the sense of increasing environmental quality and increasing employment. However, when firms choose between clean and dirty factors of production, and when there is unemployment, such a result is very likely to occur. The paper

  14. Decay Within QCD Factorization Approach

    NASA Astrophysics Data System (ADS)

    Mehraban, Hossein; Abdoos, Fahimeh

    2014-12-01

    In this paper, we have analyzed the decayin nave factorization (NF) and QCD factorization (QCDF) schemes. Since, it is known from the data analysis based on the model-independent diagrammatic approach that weak annihilation in charm decays is quite sizable, so we have calculated weak annihilation contribution which is model-dependent in the QCD factorization approach. Indeed our obtained results of decay show that the annihilation contribution is one of the key ingredients for understanding the data. Also we have calculated the branching ratio in two special scales of ?= m c , 1 GeV and two different models for the charm to an axial-vector meson transition form factors. For ISGW2 model at scale ?=1 GeV, our calculated results of the branching ratio of decay areand in the NF and QCDF, respectively. The experimental data is less than 1.910-2. The branching ratio obtained in NF is very smaller than the experimental data but in QCDF, it is compatible with experimental data.

  15. Factors Influencing Household Recycling Behavior

    Microsoft Academic Search

    Stuart Oskamp; Maura J. Harrington; Todd C. Edwards; Deborah L. Sherwood; Shawn M. Okuda; Deborah C. Swanson

    1991-01-01

    To investigate factors encouraging or deterring recycling, telephone interviews were used to study recycling behavior, attitudes, and knowledge of 221 randomly selected adults in a suburban city that had begun a citywide curbside recycling program within the past year. Approximately 40% reported participation in the curbside recycling program, and nearly 20% more claimed that their household had been recycling in

  16. Portfolio Diversification using Subspace Factorizations

    E-print Network

    Drakakis, Konstantinos

    sparse low-rank approximate factorization technique, Sparse-semiNMF, for clustering stocks into latent. The goal of this work is to learn an alternative clustering of assets in the stock market by clustering- ing assets so as to beat the stock market. Asset classes are affected by different market dynamics

  17. MODIFYING A SPARSE CHOLESKY FACTORIZATION

    Microsoft Academic Search

    TIMOTHY A. DAVIS; WILLIAM W. HAGER

    Given a sparse symmetric positive denite matrix AAT and an associated sparse Cholesky factorization LDLT or LLT, we develop sparse techniques for obtaining the new factoriza- tion associated with either adding a column to A or deleting a column from A. Our techniques are based on an analysis and manipulation of the underlying graph structure and on ideas of Gill

  18. Strategy, Contextual Factors, and Performance

    Microsoft Academic Search

    Michael A. Hitt; R. Duane Ireland

    1985-01-01

    Relationships between multiple contextual factors and performance in 185 large industrial firms were examined. Medium size, external acquisitive growth grand strategy, unit and small batch predominant production system, consumer nondurable goods industry, and high perceived environmental uncertainty were positive predictors of firm performance. Functional structure, geographic divisional structure, and large batch and mass predominant production systems were negative predictors. The

  19. Factor Simplicity Index and Transformations

    ERIC Educational Resources Information Center

    Bentler, P. M.

    1977-01-01

    A scale-invariant index of factorial simplicity is proposed as a summary statistic for principal components and factor analysis. The index ranges from zero to one, and attains its maximum when all variables are simple rather than factorially complex. (Author/JKS)

  20. EFFICIENT STRUCTURED MULTIFRONTAL FACTORIZATION FOR ...

    E-print Network

    2013-03-21

    c 2013 Society for Industrial and Applied Mathematics. Vol. 35, No. 2, pp. A832 ... methods. In particular, if the matrix arises from the discretization of certain PDEs, the factorization ... In scientific computations and engineering simulations, the .... analyzed in section 4, which shows the idea of sparse rank relaxation. Section...

  1. Psychological Risk Factors in Headache

    PubMed Central

    Nicholson, Robert A.; Houle, Timothy T.; Rhudy, Jamie L.; Norton, Peter J.

    2008-01-01

    Headache is a chronic disease that occurs with varying frequency and results in varying levels of disability. To date, the majority of research and clinical focus has been on the role of biological factors in headache and headache-related disability. However, reliance on a purely biomedical model of headache does not account for all aspects of headache and associated disability. Using a biopsychosocial framework, the current manuscript expands the view of what factors influence headache by considering the role psychological (i.e., cognitive and affective) factors have in the development, course, and consequences of headache. The manuscript initially reviews evidence showing that neural circuits responsible for cognitiveaffective phenomena are highly interconnected with the circuitry responsible for headache pain. The manuscript then reviews the influence cognitions (locus of control and self-efficacy) and negative affect (depression, anxiety, and anger) have on the development of headache attacks, perception of headache pain, adherence to prescribed treatment, headache treatment outcome, and headache-related disability. The manuscript concludes with a discussion of the clinical implications of considering psychological factors when treating headache. PMID:17371358

  2. Virulence factors of Candida species

    Microsoft Academic Search

    Yun-Liang Yang

    Candida albicans is an opportunistic human pathogen, which colonizes at several anatomically distinct sites including skin, oral, gastrointestinal tract, and vagina. How harmless commensal C. albicans become a human pathogen when opportunity comes is not clear. This review will focus on the molecular dissection of virulence factors of C. albicans, including adhesion, proteinases secretion, hyphal formation, and phenotypic switching. This

  3. Cognitive Factors in Academic Achievement.

    ERIC Educational Resources Information Center

    Cuasay, Peter

    1992-01-01

    This review explores the factors of cognitive processing, style, and metacognitive organization as they contribute to academic success. Specific discussions consider aspects of short- and long-term memory, including how these affect learning and academic performance, and the keys to attaining long-term memory capability by involving redundancy,

  4. Demographic Factors Affecting Faculty Salary

    Microsoft Academic Search

    Allen L. Webster

    1995-01-01

    This study identifies specific demographic attributes that influence salary at institutions of higher education. Data were obtained for all business faculty at nine public universities. A log-linear model with salary as the regressand serves as the functional form of estimation. Variance inflation factors are employed to reduce any aberrations that are due to the presence of multicollinearity. Additional diagnostic tests

  5. Yeast transcription factors Kevin Struhl

    E-print Network

    Yeast transcription factors Kevin Struhl Harvard Medical School, Boston, USA Studies of yeast Transcriptional regulatory mechanisms are fundamentally similar in eukaryotic organisms from yeasts to humans (for reviews of yeast transcription, see [1,2]). Compo- nents of the chromatin template and the basic RNA

  6. Factors influencing university research performance

    Microsoft Academic Search

    Fiona Edgar; Alan Geare

    2011-01-01

    This research extends our understanding of research productivity by examining features of managerial practice and culture within university departments. Adopting a robust comparative research design, capturing both interview and survey data sourced from multiple stakeholders from New Zealand universities, we seek to identify factors associated with superior research performance. The findings show that autonomy and egalitarianism, along with a strong

  7. Prognostic Factors of Krukenberg's Tumor

    Microsoft Academic Search

    Hark K. Kim; Dae S. Heo; Yung-J. Bang; Noe K. Kim

    2001-01-01

    Objective. The aim of this study was to determine prognostic factors of metachronous Krukenberg's tumors of gastric origin, thereby helping to establish a therapeutic plan for this rare entity.Methods. Thirty-four female patients who underwent curative resection of gastric carcinoma from 1987 through 1996 and subsequently developed Krukenberg's tumors were identified. The covariates used for survival analysis were patient age at

  8. Transforming Rubrics Using Factor Analysis

    ERIC Educational Resources Information Center

    Baryla, Ed; Shelley, Gary; Trainor, William

    2012-01-01

    Student learning and program effectiveness is often assessed using rubrics. While much time and effort may go into their creation, it is equally important to assess how effective and efficient the rubrics actually are in terms of measuring competencies over a number of criteria. This study demonstrates the use of common factor analysis to identify

  9. Heterogeneity of human circulating anticoagulants against antihemophilic factor (factor VIII).

    PubMed

    Poon, M C; Wine, A C; Ratnoff, O D; Bernier, G M

    1975-09-01

    The heterogeneity of human circulating anticoagulants against antihemophilic factor (AHF, factor VIII) observed in seven patients, both with and without classic hemophilia, was investigated by neutralization of their activity with antiserums directed to whole IgG and to lambda and kappa light chains. All seven anticoagulants were immunoglobulins. Six appeared to contain both kinds of light chains, although the dual light chain composition of two of these could be demonstrated only at high concentration of antiserum. In one circulating anticoagulant, light chain specificity could not be demonstrated with small amounts of antiserum, and with larger amounts, only lambda light chain specificity was revealed. Whether or not this circulating anticoagulant really contained a single light chain type could not be ascertained with our technique. The evidence presented suggested that circulating anticoagulant antibodies against AHF are polyclonal in nature. PMID:50101

  10. Relation between mobility factor and diffusion factor for thermoset cure

    Microsoft Academic Search

    Yan Meng; Sindee L. Simon

    2005-01-01

    The temperature-modulated differential scanning calorimetry (TMDSC) responses during cure of both epoxy\\/aromatic amine and dicyanate ester\\/polycyanurate systems are modeled using chemical reaction kinetics with diffusion control. Physical aging effects are incorporated into the model using the ToolNarayanaswamyMoynihan (TNM) equation. We investigate the assumption that the mobility factor, which may be obtained from experimental temperature-modulated differential scanning calorimetry reversing heat flow

  11. Sequential coagulation factor VIIa domain binding to tissue factor

    SciTech Connect

    Oesterlund, Maria [IFM-Department of Chemistry, Linkoeping University, SE-581 83 Linkoping (Sweden); Persson, Egon [Vascular Biochemistry, Novo Nordisk A/S, DK-2760 Malov (Denmark); Carlsson, Uno [IFM-Department of Chemistry, Linkoeping University, SE-581 83 Linkoping (Sweden); Freskgard, Per-Ola [Protein Biotechnology, Novo Nordisk A/S, DK-2880 Bagsvaerd (Denmark)]. E-mail: Per-Ola.Freskgard@astrazeneca.com; Svensson, Magdalena [IFM-Department of Chemistry, Linkoeping University, SE-581 83 Linkoping (Sweden)]. E-mail: msv@ifm.liu.se

    2005-12-02

    Vessel wall tissue factor (TF) is exposed to blood upon vascular damage which enables association with factor VIIa (FVIIa). This leads to initiation of the blood coagulation cascade through localization and allosteric induction of FVIIa procoagulant activity. To examine the docking pathway of the FVIIa-TF complex, various residues in the extracellular part of TF (sTF) that are known to interact with FVIIa were replaced with cysteines labelled with a fluorescent probe. By using stopped-flow fluorescence kinetic measurements in combination with surface plasmon resonance analysis, we studied the association of the resulting sTF variants with FVIIa. We found the docking trajectory to be a sequence of events in which the protease domain of FVIIa initiates contact with sTF. Thereafter, the two proteins are tethered via the first epidermal growth factor-like and finally the {gamma}-carboxyglutamic acid (Gla) domain. The two labelled sTF residues interacting with the protease domain of FVIIa bind or become eventually ordered at different rates, revealing kinetic details pertinent to the allosteric activation of FVIIa by sTF. Moreover, when the Gla domain of FVIIa is removed the difference in the rate of association for the remaining domains is much more pronounced.

  12. Basic Fibroblastic Growth Factor as a Potential Meningeal Angiogenic Factor

    PubMed Central

    Olson, Jeffrey J.; Reisner, Andrew; Klemm, Joyce M.; Bakay, Roy A. E.

    1993-01-01

    Vascular supply plays a significant role in the management of skull base tumors. The diagnosis is aided by contrast-enhanced imaging and angiographic techniques, and embolization procedures are used to devascularize certain lesions. The degree of surgical technical difficulty is strongly influenced by the degree of tumor vascularity. Although the importance of this blood supply is clearly understood, the mechanism involved in developing a system of tumor-perfusing vessels is yet to be defined. The development of a vascular network, or angiogenesis, is an important event in allowing tumor proliferation to progress beyond small clusters of cells. Basic fibroblastic growth factor (bFGF) is an especially attractive candidate as an angiogenic growth factor because of its ability to stimulate processes that are characteristic of angiogenesis in vitro. Tumors that involve the meninges may have the ability to liberate normally stored bFGF, which may, in turn, induce new vessel formation for continued tumor proliferation. An immunohistochemical analysis of rodent and bovine meninges to study this phenomenon is described. The dura, arachnoid, and their associated vessels are shown clearly to contain this growth factor. Ultimately, an adjuvant therapy based on the inhibition of angiogenesis may provide a reasonable alternative to aggressive surgical approaches in skull base tumors that are incompletely resectable. ImagesFigure 1Figure 2 PMID:17170900

  13. A synoptic study of phytoplankton in the deep lakes south of the Alps (lakes Garda, Iseo, Como, Lugano and Maggiore)

    Microsoft Academic Search

    Nico SALMASO; Giuseppe MORABITO; Rosario MOSELLO; Letizia GARIBALDI; Marco SIMONA; Fabio BUZZI; Delio RUGGIU

    This paper presents a synoptic account of the most important results emerging from studies on the phytoplankton communities in the deep southern subalpine lakes Garda, Iseo, Como, Lugano and Maggiore (DSL) in the second half of the 1990s. At present, the trophogenic layers of these lakes are trophically different, ranging from the oligo-mesotrophy of lakes Maggiore and Garda to the

  14. Analise do Impacto da Rede Social na Marcac~ao de Fotos como Favoritas no Flickr1

    E-print Network

    Cirne, Walfredo

    Analise do Impacto da Rede Social na Marcac~ao de Fotos como Favoritas no Flickr1 Luiz Alves favoritos. Neste trabalho analisamos o impacto da rede de contatos na avaliac~ao de fotos utilizando dados da rede social Flickr1 , um dos mais importantes sites de compartilhamento de fotos, que possui milh

  15. EL PORTAFOLIO VIRTUAL COMO ESTRATEGIA DIDACTICO-METODOLGICA Y DE EVALUACIN EN LA ENSEANZA UNIVERSITARIA SEMIPRESENCIAL Y A DISTANCIA

    Microsoft Academic Search

    Ramn Prez Prez

    Resumo: Na atualidade a educao superior se v submetida a numerosos processos de mudana que vm determinados por mltiplas variveis que a fazem mais complexa, adicionando assim complexidade os processo que devem acontecer no sala de aula com relao ao que cabe esperar tanto do corpo discente como do prprio professorado. A globalizao, a competitividade, as exigncias dos sistemas de

  16. Las mesas de trabajo ambiental como estrategia de autoformacin y fortalecimiento del liderazgo docente: una experiencia de cooperacin

    Microsoft Academic Search

    Alfredo Antonio pupo Gomez; Mara Teresa Holgun Aguirre

    2010-01-01

    RESUMEN Para el desarrollo de los Proyectos Ambientales Escolares en la Localidad de Suba, se implement como estrategia de trabajo participativo la Mesa Educacin Ambiental Local - MEAL, en donde participan las instituciones educativas de la Localidad de Suba Bogot D.C., bajo la orientacin del Centro Administrativo de Educacin Local - CADEL 11 y la Universidad Libre, en el marco

  17. GESTIN EMPRESARIAL ORIENTADA AL VALOR DEL CLIENTE COMO FUENTE DE VENTAJA COMPETITIVA. PROPUESTA DE UN MODELO EXPLICATIVO

    Microsoft Academic Search

    LESLIER VALENZUELA; EDUARDO TORRES

    2008-01-01

    La globalizacin y el entorno altamente competitivo exigen a las empresas estar orientadas al mercado y gestionar su cartera de clientes como un activo estratgico clave para aumentar la rentabilidad del negocio y lograr una ventaja competitiva sostenible en el tiempo. El objetivo de este artculo es contribuir con una propuesta de modelo basado en el valor de la cartera

  18. La valoracin econmica de bienes y servicios ambientales como herramienta estrategica para la conservacin y uso sostenible de los ecosistemas

    Microsoft Academic Search

    ADOLFO CARBAL HERRERA

    2010-01-01

    Resumen El trabajo corresponde a un estudio piloto hacia la implementacin de una metodologa que permita aproximar el valor monetario de los Bienes y Servicios Ambientales (BSA) ofertados por un ecosistema hdrico, caso Cinaga de la Caimanera, municipio de Coveas, departamento de Sucre-Colombia, como herramienta estratgica para incentivar la conservacin y uso sostenible de los ecosistemas. Avanzar en procesos de

  19. High Factor VIII and Von Willebrand Factor Levels Are Not Risk Factors of Cryptogenic Arterial Ischemic Stroke in Thai Children.

    PubMed

    Sirachainan, Nongnuch; Boonyatarp, Manasjitt; Kadegasem, Praguywan; Sasanakul, Werasak; Visudtibhan, Anannit; Natesirinilkul, Rungrote; Chuansumrit, Ampaiwan; Wongwerawattanakoon, Pakawan

    2015-07-01

    High factor VIII levels and a risk factor of arterial ischemic stroke is controversial. Levels of factor VIII depend on ethnicity, age, and sex. This report included 24 Thai children with cryptogenic arterial ischemic stroke and 41 controls, with a mean (standard deviation) age of 11.5 (6.3) and 9.0 (4.7), respectively. The study was performed during the post-arterial ischemic stroke events to avoid acute phase reaction of factor VIII and von Willebrand factor. The levels of factor VIII activity and von Willebrand factor antigen in patients were not significantly different compared to controls (119.8 41.3% vs 138.0 48.7%, P = .29 and 92.8 29.8% vs 103.7 39.1%, P = .4, respectively). Therefore, high factor VIII and von Willebrand factor antigen levels were not risk factors of cryptogenic arterial ischemic stroke in Thai children. PMID:25038134

  20. FACTORING FACTOR MAPS Abstract. A noninjective boundedtoone factor map from an irreducible shift of

    E-print Network

    Boyle, Mike

    a resolving map between two given irreducible shifts of finite type (SFT's) was solved by Ashley [3 if boundedtoone factor maps between irreducible SFT's are always compositions of resolving maps, a question the possibility that a system is a quotient of an SFT. As another we prove a proposition (4.3) useful

  1. Factors Influencing Attitude of Youth Towards Entrepreneurship

    Microsoft Academic Search

    E. A. Dioneo-Adetayo

    2006-01-01

    The study was carried out to investigate the attitude of youth towards entrepreneurship programs. It was aimed at identifying the capacity factors of potential youth entrepreneurs and the critical external factors influencing their attitude towards entrepreneurship programs. It was also aimed at determining the level of influence of these factors and identifying the perceived enhancing factors and inhibitions on the

  2. A Kilobit Special Number Field Sieve Factorization

    Microsoft Academic Search

    Kazumaro Aoki; Jens Franke; Thorsten Kleinjung; Arjen K. Lenstra; Dag Arne Osvik

    2007-01-01

    We describe how we reached a new factoring milestone by completing the first special number field sieve factorization of a number having more than 1024 bits, namely the Mersenne number 21039 1. Although this factorization is orders of magnitude 'easier' than a factorization of a 1024-bit RSA modulus is believed to be, the methods we used to obtain our result

  3. Confirmatory Analysis of Exploratively Obtained Factor Structures

    Microsoft Academic Search

    Jan-Willem van Prooijen; Willem A. van der Kloot

    2001-01-01

    Factor structures obtained by exploratory factor analysis (EFA) often turn out to fit poorly in confirmative follow-up studies. In the present study, the authors assessed the extent to which results obtained in EFA studies can be replicated by confirmatory factor analysis (CFA) in the same sample. More specifically, the authors used CFA to test three different factor models on several

  4. NUIT Tech Talk: Multi-factor Authentication

    E-print Network

    Ottino, Julio M.

    and app 1. Download the free DUO Mobile app 2. Enter and confirm your phone number 3. Receive a oneNUIT Tech Talk: Multi-factor Authentication November 20, 2014 Roger Safian Data Security Analyst is Multi-factor Authentication? Multi-factor at Northwestern Benefits of Using Multi-factor How Do

  5. Bayesian Estimation of Categorical Dynamic Factor Models

    ERIC Educational Resources Information Center

    Zhang, Zhiyong; Nesselroade, John R.

    2007-01-01

    Dynamic factor models have been used to analyze continuous time series behavioral data. We extend 2 main dynamic factor model variations--the direct autoregressive factor score (DAFS) model and the white noise factor score (WNFS) model--to categorical DAFS and WNFS models in the framework of the underlying variable method and illustrate them with

  6. 28 CFR 51.57 - Relevant factors.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Relevant factors. Among the factors the Attorney General will...the change; and (e) The factors set forth in Village of Arlington...1977): (1) Whether the impact of the official action bears...departures from the normal factors considered; and (6)...

  7. 28 CFR 51.57 - Relevant factors.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Relevant factors. Among the factors the Attorney General will...the change; and (e) The factors set forth in Village of Arlington...1977): (1) Whether the impact of the official action bears...departures from the normal factors considered; and (6)...

  8. 28 CFR 51.57 - Relevant factors.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Relevant factors. Among the factors the Attorney General will...the change; and (e) The factors set forth in Village of Arlington...1977): (1) Whether the impact of the official action bears...departures from the normal factors considered; and (6)...

  9. 28 CFR 51.57 - Relevant factors.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Relevant factors. Among the factors the Attorney General will...the change; and (e) The factors set forth in Village of Arlington...1977): (1) Whether the impact of the official action bears...departures from the normal factors considered; and (6)...

  10. Factor Structure of the Psychopathology Checklist.

    ERIC Educational Resources Information Center

    Harpur, Timothy J.; And Others

    1988-01-01

    Examined whether Psychopathology Checklist contains stable and replicable factor structure by factor-analyzing data from male prisoners (N=1,119) in Canada, United States, and England. Found two-factor solution replicated in all samples. Factor 1 defined by personality traits: superficiality; habitual lying/manipulation; callousness; lack of

  11. fi- R Factors giving Chloramphenicol Resistance

    Microsoft Academic Search

    R. W. Hedges; Naomi Datta

    1971-01-01

    ALTHOUGH many fi+ R factors confer resistance to chloramphenicol, fi- R factors seldom do. Watanabe et al.1 stated in 1964 that all the naturally occurring fi- R factors which they had studied lacked chloramphenicol resistance. In our laboratory, no fi- R factor giving chloramphenicol resistance has been observed among several hundred drug-resistant strains of enteric bacteria. In 1968 Watanabe, Furuse

  12. Graybody Factors and Infrared Divergences

    NASA Astrophysics Data System (ADS)

    Anderson, Paul; Fabbri, Alessandro; Balbinot, Roberto; Parentani, Renaud

    2015-04-01

    A method of computing the gray-body factors for static spherically symmetric and BEC acoustic black holes using a Volterra integral equation is given. The results are used to investigate infrared divergences in the particle number, two-point function, point-split stress-energy tensor and density-density correlation function. Infrared divergences in the particle number and two-point function occur if the gray-body factor approaches a nonzero constant in the zero frequency limit, as happens for Schwarzschild-de Sitter black holes and BEC acoustic black holes. However, no infrared divergences occur in the point-split stress-energy tensor or the density-density correlation function. Supported in part by the National Science Foundation under Grant Nos. PHY-0856050 and PHY-1308325.

  13. Human Factors and Medical Devices

    SciTech Connect

    Dick Sawyer

    1998-12-31

    Medical device hardware- and software-driven user interfaces should be designed to minimize the likelihood of use-related errors and their consequences. The role of design-induced errors in medical device incidents is attracting widespread attention. The U.S. Food and Drug Administration (FDA) is fully cognizant that human factors engineering is critical to the design of safe medical devices, and user interface design is receiving substantial attention by the agency. Companies are paying more attention to the impact of device design, including user instructions, upon the performance of those health professionals and lay users who operate medical devices. Concurrently, the FDA is monitoring human factors issues in its site inspections, premarket device approvals, and postmarket incident evaluations. Overall, the outlook for improved designs and safer device operation is bright.

  14. Factors contributing to adolescent obesity.

    PubMed

    Al-Kloub, Manal I; Froelicher, Erika S

    2009-06-01

    Obesity in children is a significant public health concern. The prevalence of overweight and obesity in Jordanian children, and adolescents has increased in the last decade. The consequences of obesity to health in childhood and adulthood have both medical, and economic cost to individuals and society. This paper reviews the factors that contribute to adolescent obesity and emphasizes behavioral and environmental factors. An individual's behaviors such as increased consumption of high caloric foods, increased sedentary activity while decreasing physical activity has been identified as key issues in the development of obesity. Additionally, the current environment in homes, schools, and neighborhoods tend to discourage a healthy lifestyle. A comprehensive approach that involves the whole community is the best strategy for preventing adolescent obesity. Nurses are in a unique position to provide leadership in developing programs for healthier lifestyle choices for adolescents' and adoption of these goals into their daily lives. PMID:19526153

  15. Factors Impacting Decommissioning Costs - 13576

    SciTech Connect

    Kim, Karen; McGrath, Richard [Electric Power Research Institute, 3420 Hillview Ave., Palo Alto, California (United States)] [Electric Power Research Institute, 3420 Hillview Ave., Palo Alto, California (United States)

    2013-07-01

    The Electric Power Research Institute (EPRI) studied United States experience with decommissioning cost estimates and the factors that impact the actual cost of decommissioning projects. This study gathered available estimated and actual decommissioning costs from eight nuclear power plants in the United States to understand the major components of decommissioning costs. Major costs categories for decommissioning a nuclear power plant are removal costs, radioactive waste costs, staffing costs, and other costs. The technical factors that impact the costs were analyzed based on the plants' decommissioning experiences. Detailed cost breakdowns by major projects and other cost categories from actual power plant decommissioning experiences will be presented. Such information will be useful in planning future decommissioning and designing new plants. (authors)

  16. Factors influencing susceptibility to metals.

    PubMed Central

    Gochfeld, M

    1997-01-01

    Although the long-neglected field of human susceptibility to environmental toxicants is currently receiving renewed attention, there is only scant literature on factors influencing susceptibility to heavy metals. Genetic factors may influence the availability of sulfhydryl-containing compounds such as glutathione and metallothionein, which modify the distribution and toxicity of certain metals. Age and gender play a role in modifying uptake and distribution, although the mechanisms are often obscure. Concurrent exposure to divalent cations may enhance or reduce the toxicity of certain metals through competition for receptor-mediated transport or targets. Increasing use of biomarkers of exposure should greatly increase our understanding of the underlying distribution of susceptibility to various environmental agents. PMID:9255566

  17. Human factors in waste management

    SciTech Connect

    Moray, N. [Univ. of Illinois, Urbana, IL (United States)

    1994-10-01

    This article examines the role of human factors in radioactive waste management. Although few problems and ergonomics are special to radioactive waste management, some problems are unique especially with long term storage. The entire sociotechnical system must be looked at in order to see where improvement can take place because operator errors, as seen in Chernobyl and Bhopal, are ultimately the result of management errors.

  18. Provider Factors in Healthcare Disparities

    Microsoft Academic Search

    Michael Christopher Gibbons

    Several factors related to healthcare providers may be associated with healthcare disparities. Communication is fundamental\\u000a to the healthcare process. Patientprovider communication is a multidimensional concept relating in part to both providers\\u000a and patients. This chapter will discuss those aspects of patientprovider communication more closely related to the provider.\\u000a Chapter 3 will discuss those patient-provider communication issues more closely related to

  19. Pharmacologic Factors Affecting Glycemic Control

    Microsoft Academic Search

    Lillian F. Lien

    Among many challenges to achieving and maintaining glycemic control, the impact of pharmacologic agents on glycemia is a significant,\\u000a but often overlooked factor. Numerous medications have been implicated in the development of drug-induced hyperglycemia and\\u000a type 2 diabetes mellitus. Of these, the atypical antipsychotics (for the management of depression and psychosis), the protease-inhibitor\\u000a anti retroviral agents (for the management of

  20. On factorization of multiparticle pentagons

    E-print Network

    A. V. Belitsky

    2015-05-21

    We address the near-collinear expansion of multiparticle NMHV amplitudes, namely, the heptagon and octagons in the dual language of null polygonal super Wilson loops. In particular, we verify multiparticle factorization of charged pentagon transitions in terms of pentagons for single flux-tube excitations within the framework of refined operator product expansion. We find a perfect agreement with available tree and one-loop data.

  1. On factorization of multiparticle pentagons

    E-print Network

    Belitsky, A V

    2015-01-01

    We address the near-collinear expansion of multiparticle non-MHV amplitudes, namely, the heptagon and octagons in the dual language of null polygonal super Wilson loops. In particular, we verify multiparticle factorization of charged pentagon transitions in terms of pentagons for single flux-tube excitations within the framework of refined operator product expansion. We find a perfect agreement with available tree and one-loop data.

  2. Human Factors and Medical Devices

    Microsoft Academic Search

    Dick Sawyer

    1998-01-01

    Medical device hardware- and software-driven user interfaces should be designed to minimize the likelihood of use-related errors and their consequences. The role of design-induced errors in medical device incidents is attracting widespread attention. The U.S. Food and Drug Administration (FDA) is fully cognizant that human factors engineering is critical to the design of safe medical devices, and user interface design

  3. Human Factors in Space Exploration

    NASA Technical Reports Server (NTRS)

    Jones, Patricia M.; Fiedler, Edna

    2010-01-01

    The exploration of space is one of the most fascinating domains to study from a human factors perspective. Like other complex work domains such as aviation (Pritchett and Kim, 2008), air traffic management (Durso and Manning, 2008), health care (Morrow, North, and Wickens, 2006), homeland security (Cooke and Winner, 2008), and vehicle control (Lee, 2006), space exploration is a large-scale sociotechnical work domain characterized by complexity, dynamism, uncertainty, and risk in real-time operational contexts (Perrow, 1999; Woods et ai, 1994). Nearly the entire gamut of human factors issues - for example, human-automation interaction (Sheridan and Parasuraman, 2006), telerobotics, display and control design (Smith, Bennett, and Stone, 2006), usability, anthropometry (Chaffin, 2008), biomechanics (Marras and Radwin, 2006), safety engineering, emergency operations, maintenance human factors, situation awareness (Tenney and Pew, 2006), crew resource management (Salas et aI., 2006), methods for cognitive work analysis (Bisantz and Roth, 2008) and the like -- are applicable to astronauts, mission control, operational medicine, Space Shuttle manufacturing and assembly operations, and space suit designers as they are in other work domains (e.g., Bloomberg, 2003; Bos et al, 2006; Brooks and Ince, 1992; Casler and Cook, 1999; Jones, 1994; McCurdy et ai, 2006; Neerincx et aI., 2006; Olofinboba and Dorneich, 2005; Patterson, Watts-Perotti and Woods, 1999; Patterson and Woods, 2001; Seagull et ai, 2007; Sierhuis, Clancey and Sims, 2002). The human exploration of space also has unique challenges of particular interest to human factors research and practice. This chapter provides an overview of those issues and reports on sorne of the latest research results as well as the latest challenges still facing the field.

  4. Factoring integers with elliptic curves

    Microsoft Academic Search

    H. W. Lenstra

    1987-01-01

    Abstract This paper is devoted to the description and analysis of a new algorithm to factor positive integers. It depends on the use of elliptic curves. The new method is obtained from,Pollard's (p l)-method (Proc. Cambridge,Philos. Soc. 76 (1974), 521-528) by replacing the multiplicative group by the group of points on a random,elliptic curve. It is conjectured,that the algorithm,determines,a

  5. Lifestyle factors and sperm aneuploidy.

    PubMed

    Jurewicz, Joanna; Radwan, Micha?; Sobala, Wojciech; Radwan, Pawe?; Jakubowski, Lucjusz; Hawu?a, Wanda; Ula?ska, Anna; Hanke, Wojciech

    2014-09-01

    Different environmental and lifestyle factors may interfere with the normal disjunction of sister chromatids/chromosomes during meiosis and may cause aneuploidy. The aim of the study was to examine the association between lifestyle factors and sperm aneuploidy. The study population consisted of 212 healthy men under 45 years of age attending an infertility clinic for diagnostic purposes and who had a normal semen concentration of 20-30010?mL or slight oligozoospermia (semen concentration of 15-2010?/mL). All participants were interviewed and provided a semen sample. Sperm aneuploidy was assessed using multicolor FISH (DNA probes specific for chromosomes X, Y, 18, 13, 21). Results from the study suggest that lifestyle factors are related to sperm aneuploidy. A positive relationship was found between coffee drinking everyday and the lack of chromosome X or Y, as well as coffee drinking 1-6 times per week and additional chromosome 18. Wearing boxer shorts decrease the copy number changes in the whole chromosome 18, the number of additional chromosome 18 and the lack of chromosome 13. Additionally, obesity (BMI 30-40 kg/m) was positively associated with additional chromosome 21 after being adjusted for potential confounders. These findings demonstrate that changing the men's lifestyle habits may contribute to reduction of the incidence of sperm aneuploidy. It is necessary that men continue to follow sensible health advice concerning excess weight, coffee drinking and wearing tight fitting underwear. As this is the first such study to examine different lifestyle factors and sperm aneuploidy, the results need to be confirmed on larger population. PMID:25152516

  6. Human factors in incident reporting

    NASA Technical Reports Server (NTRS)

    Jones, S. G.

    1993-01-01

    The paper proposes a cooperative research effort be undertaken by academic institutions and industry organizations toward the compilation of a human factors data base in conjunction with technical information. Team members in any discipline can benefit and learn from observing positive examples of decision making and performance by crews under stressful or less than optimal circumstances. The opportunity to note trends in interpersonal and interactive behaviors and to categorize them is terms of more or less desirable outcomes should not be missed.

  7. Factor weighting in DRASTIC modeling.

    PubMed

    Pacheco, F A L; Pires, L M G R; Santos, R M B; Sanches Fernandes, L F

    2015-02-01

    Evaluation of aquifer vulnerability comprehends the integration of very diverse data, including soil characteristics (texture), hydrologic settings (recharge), aquifer properties (hydraulic conductivity), environmental parameters (relief), and ground water quality (nitrate contamination). It is therefore a multi-geosphere problem to be handled by a multidisciplinary team. The DRASTIC model remains the most popular technique in use for aquifer vulnerability assessments. The algorithm calculates an intrinsic vulnerability index based on a weighted addition of seven factors. In many studies, the method is subject to adjustments, especially in the factor weights, to meet the particularities of the studied regions. However, adjustments made by different techniques may lead to markedly different vulnerabilities and hence to insecurity in the selection of an appropriate technique. This paper reports the comparison of 5 weighting techniques, an enterprise not attempted before. The studied area comprises 26 aquifer systems located in Portugal. The tested approaches include: the Delphi consensus (original DRASTIC, used as reference), Sensitivity Analysis, Spearman correlations, Logistic Regression and Correspondence Analysis (used as adjustment techniques). In all cases but Sensitivity Analysis, adjustment techniques have privileged the factors representing soil characteristics, hydrologic settings, aquifer properties and environmental parameters, by leveling their weights to ?4.4, and have subordinated the factors describing the aquifer media by downgrading their weights to ?1.5. Logistic Regression predicts the highest and Sensitivity Analysis the lowest vulnerabilities. Overall, the vulnerability indices may be separated by a maximum value of 51 points. This represents an uncertainty of 2.5 vulnerability classes, because they are 20 points wide. Given this ambiguity, the selection of a weighting technique to integrate a vulnerability index may require additional expertise to be set up satisfactorily. Following a general criterion that weights must be proportional to the range of the ratings, Correspondence Analysis may be recommended as the best adjustment technique. PMID:25461049

  8. Scalable Variational Bayesian Matrix Factorization

    E-print Network

    Choi, Seungjin

    .9175/ 4 0.9217/ 4 0.9314/ 4 0.9431/ 3 Netflix probe10 RMSE/optimal number of epohcs of the BRSIMF(V) Likelihood P(X |U,V) Posterior P(U,V |X) MCMC on Netflix Approximate the posterior by MCMC (Salakhutdinov 12 Element-wisely factorized variational distribution K=100 O((I+J)(K+K2)) O(2(I+J)K) Netflix I = 480

  9. [Prognostic factors in malignant gliomas].

    PubMed

    Ushio, Y; Kochi, M

    1996-04-01

    The most important prognostic factor in malignant gliomas is histopathological diagnosis of the tumor. The survival of patients with anaplastic astrocytoma is much longer than that of patients with glioblastoma. The median survival of the former has been improved up to almost 4 years by the recent progress of multidisciplinary treatment, whereas that of the latter has still remained in less than 1.5 years. Other important factors proved to be associated with survival of patients with malignant gliomas are the age of patients, Karnofsky performance status on admission, surgery, radiotherapy and chemotherapy. There is substantial evidence suggesting an association between younger patient age and longer survival in adults with supratentorial anaplastic astrocytoma as well as glioblastoma. It is also consistent with evidence that the patients with better performance status on admission live longer after treatment. Gross total resection of supratentorial anaplastic astrocytoma is directly associated with longer and better survival when compared to subtotal or partial resection. For glioblastoma, however, gross total resection has not been proved to have a significant survival advantage over subtotal or partial removal. Radiotherapy has been proved to be associated with longer survival of patients with supratentorial anaplastic astrocytoma and glioblastoma. Chemotherapy has not proved effective in prolonging the survival of patients with glioblastoma. Multidrug chemotherapy with CCNU, procarbazine and vincristine has proved to have significant survival advantage over BCNU alone, suggesting chemotherapy is also a prognostic factor in patients with anaplastic astrocytoma. PMID:8678527

  10. Quantum Computers, Factoring, and Decoherence

    E-print Network

    I. Chuang; Raymond Laflamme; P. Shor; W. Zurek

    1995-03-08

    In a quantum computer any superposition of inputs evolves unitarily into the corresponding superposition of outputs. It has been recently demonstrated that such computers can dramatically speed up the task of finding factors of large numbers -- a problem of great practical significance because of its cryptographic applications. Instead of the nearly exponential ($\\sim \\exp L^{1/3}$, for a number with $L$ digits) time required by the fastest classical algorithm, the quantum algorithm gives factors in a time polynomial in $L$ ($\\sim L^2$). This enormous speed-up is possible in principle because quantum computation can simultaneously follow all of the paths corresponding to the distinct classical inputs, obtaining the solution as a result of coherent quantum interference between the alternatives. Hence, a quantum computer is sophisticated interference device, and it is essential for its quantum state to remain coherent in the course of the operation. In this report we investigate the effect of decoherence on the quantum factorization algorithm and establish an upper bound on a ``quantum factorizable'' $L$ based on the decoherence suffered per operational step.

  11. Inhibitors - genetic and environmental factors.

    PubMed

    Lillicrap, D; Fijnvandraat, K; Santagostino, E

    2014-05-01

    It is known that a large number of both genetic and environmental factors contribute to the risk of inhibitor development, but underlying pathogenetic mechanisms are still under investigation. The clinical research on inhibitors towards factor VIII (FVIII) is challenged by the fact that this is an infrequent event occurring in a rare disease. Therefore, it is widely accepted that complementary studies involving animal models can provide important insights into the pathogenesis and treatment of this complication. In this respect, mouse models have been studied for clues to FVIII immunogenicity, natural history of immunity and for different approaches to primary and secondary tolerance induction. In the clinical setting, the type of FVIII product used and the occurrence of product switching are considered important factors which may have an influence on inhibitor development. The evaluation of data currently available in the literature does not prove unequivocally that a difference in the immunogenicity exists between particular FVIII products (e.g. recombinant vs. plasma-derived, full length vs. B-domainless). In addition, national products switches have occurred and, in this context, switching was not associated with an enhanced inhibitor risk. In contrast with severe haemophilia A, patients with moderate and mild haemophilia A receive FVIII treatment infrequently for bleeds or surgery. In this condition the inhibitor risk is low but remains present lifelong, requiring continuous vigilance, particularly after intensive FVIII exposure. PMID:24762282

  12. Environmental factors in multiple sclerosis.

    PubMed

    Pantazou, Vasiliki; Schluep, Myriam; Du Pasquier, Renaud

    2015-04-01

    Although multiple sclerosis (MS) is recognized as a disorder involving the immune system, the interplay of environmental factors and individual genetic susceptibility seems to influence MS onset and clinical expression, as well as therapeutic responsiveness. Multiple human epidemiological and animal model studies have evaluated the effect of different environmental factors, such as viral infections, vitamin intake, sun exposure, or still dietary and life habits on MS prevalence. Previous Epstein-Barr virus infection, especially if this infection occurs in late childhood, and lack of vitamin D (VitD) currently appear to be the most robust environmental factors for the risk of MS, at least from an epidemiological standpoint. Ultraviolet radiation (UVR) activates VitD production but there are also some elements supporting the fact that insufficient UVR exposure during childhood may represent a VitD-independent risk factor of MS development, as well as negative effect on the clinical and radiological course of MS. Recently, there has been a growing interest in the gut-brain axis, a bidirectional neuro-hormonal communication system between the intestinal microbiota and the central nervous system (CNS). Indeed, components of the intestinal microbiota may be pro-inflammatory, promote the migration of immune cells into the CNS, and thus be a key parameter for the development of autoimmune disorders such as MS. Interestingly most environmental factors seem to play a role during childhood. Thus, if childhood is the most fragile period to develop MS later in life, preventive measures should be applied early in life. For example, adopting a diet enriched in VitD, playing outdoor and avoiding passive smoking would be extremely simple measures of primary prevention for public health strategies. However, these hypotheses need to be confirmed by prospective evaluations, which are obviously difficult to conduct. In addition, it remains to be determined whether and how VitD supplementation in adult life would be useful in alleviating the course of MS, once this disease has already started. A better knowledge of the influence of various environmental stimuli on MS risk and course would certainly allow the development of add-on therapies or measures in parallel to the immunotherapies currently used in MS. PMID:25744944

  13. Scene kinetics mitigation using factor analysis with derivative factors.

    SciTech Connect

    Larson, Kurt W.; Melgaard, David Kennett; Scholand, Andrew Joseph

    2010-07-01

    Line of sight jitter in staring sensor data combined with scene information can obscure critical information for change analysis or target detection. Consequently before the data analysis, the jitter effects must be significantly reduced. Conventional principal component analysis (PCA) has been used to obtain basis vectors for background estimation; however PCA requires image frames that contain the jitter variation that is to be modeled. Since jitter is usually chaotic and asymmetric, a data set containing all the variation without the changes to be detected is typically not available. An alternative approach, Scene Kinetics Mitigation, first obtains an image of the scene. Then it computes derivatives of that image in the horizontal and vertical directions. The basis set for estimation of the background and the jitter consists of the image and its derivative factors. This approach has several advantages including: (1) only a small number of images are required to develop the model, (2) the model can estimate backgrounds with jitter different from the input training images, (3) the method is particularly effective for sub-pixel jitter, and (4) the model can be developed from images before the change detection process. In addition the scores from projecting the factors on the background provide estimates of the jitter magnitude and direction for registration of the images. In this paper we will present a discussion of the theoretical basis for this technique, provide examples of its application, and discuss its limitations.

  14. Understanding adverse events: human factors.

    PubMed Central

    Reason, J

    1995-01-01

    (1) Human rather than technical failures now represent the greatest threat to complex and potentially hazardous systems. This includes healthcare systems. (2) Managing the human risks will never be 100% effective. Human fallibility can be moderated, but it cannot be eliminated. (3) Different error types have different underlying mechanisms, occur in different parts of the organisation, and require different methods of risk management. The basic distinctions are between: Slips, lapses, trips, and fumbles (execution failures) and mistakes (planning or problem solving failures). Mistakes are divided into rule based mistakes and knowledge based mistakes. Errors (information-handling problems) and violations (motivational problems) Active versus latent failures. Active failures are committed by those in direct contact with the patient, latent failures arise in organisational and managerial spheres and their adverse effects may take a long time to become evident. (4) Safety significant errors occur at all levels of the system, not just at the sharp end. Decisions made in the upper echelons of the organisation create the conditions in the workplace that subsequently promote individual errors and violations. Latent failures are present long before an accident and are hence prime candidates for principled risk management. (5) Measures that involve sanctions and exhortations (that is, moralistic measures directed to those at the sharp end) have only very limited effectiveness, especially so in the case of highly trained professionals. (6) Human factors problems are a product of a chain of causes in which the individual psychological factors (that is, momentary inattention, forgetting, etc) are the last and least manageable links. Attentional "capture" (preoccupation or distraction) is a necessary condition for the commission of slips and lapses. Yet, its occurrence is almost impossible to predict or control effectively. The same is true of the factors associated with forgetting. States of mind contributing to error are thus extremely difficult to manage; they can happen to the best of people at any time. (7) People do not act in isolation. Their behaviour is shaped by circumstances. The same is true for errors and violations. The likelihood of an unsafe act being committed is heavily influenced by the nature of the task and by the local workplace conditions. These, in turn, are the product of "upstream" organisational factors. Great gains in safety can ve achieved through relatively small modifications of equipment and workplaces. (8) Automation and increasing advanced equipment do not cure human factors problems, they merely relocate them. In contrast, training people to work effectively in teams costs little, but has achieved significant enhancements of human performance in aviation. (9) Effective risk management depends critically on a confidential and preferable anonymous incident monitoring system that records the individual, task, situational, and organisational factors associated with incidents and near misses. (10) Effective risk management means the simultaneous and targeted deployment of limited remedial resources at different levels of the system: the individual or team, the task, the situation, and the organisation as a whole. PMID:10151618

  15. Modifications of Coronary Risk Factors

    PubMed Central

    Albu, Jeanine; Gottlieb, Sheldon H.; August, Phyllis; Nesto, Richard W.; Orchard, Trevor J.

    2009-01-01

    In addition to the revascularization and glycemic management interventions assigned at random, the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) design includes the uniform control of major coronary artery disease risk factors, including dyslipidemia, hypertension, smoking, central obesity, and sedentary lifestyle. Target levels for risk factors were adjusted throughout the trial to comply with changes in recommended clinical practice guidelines. At present, the goals are low-density lipoprotein cholesterol <2.59 mmol/L (<100 mg/dL) with an optional goal of <1.81 mmol/L (<70 mg/dL); plasma triglyceride level <1.70 mmol/L (<150 mg/dL); blood pressure level <130 mm Hg systolic and <80 mm Hg diastolic; and smoking cessation treatment for all active smokers. Algorithms were developed for the pharmacologic management of dyslipidemia and hypertension. Dietary prescriptions for the management of glycemia, plasma lipid profiles, and blood pressure levels were adapted from existing clinical practice guidelines. Patients with a body mass index >25 were prescribed moderate caloric restriction; after the trial was under way, a lifestyle weight-management program was instituted. All patients were formally prescribed both endurance and resistance/flexibility exercises, individually adapted to their level of disability and fitness. Pedometers were distributed as a biofeedback strategy. Strategies to achieve the goals for risk factors were designed by BARI 2D working groups (lipid, cardiovascular and hypertension, and nonpharmacologic intervention) and the ongoing implementation of the strategies is monitored by lipid, hypertension, and lifestyle intervention management centers. PMID:16813737

  16. Electrical and Production Load Factors

    E-print Network

    Sen, T.; Heffington, W. M.

    for each shift classification within major industry groups. The load factor based on billing hours (ELF) increases with operating hours from about 0.4 for a nominal one shift operation, to about 0.7 for around-the-clock operation. On the other hand... the corresponding ELF values. This analysis used annual data for electrical demand and consumption along with annual operating hours for manufacturing facilities in the United States from the US Department of Energy?s Industrial Assessment Center national...

  17. Factors Affecting the Earth's Weather

    NSDL National Science Digital Library

    This Classroom Connectors lesson plan discusses factors affecting the weather on Earth. Students learn about solar radiation, wind circulation, precipitation, and biomes that result from weather patterns. The site provides goals, objectives, an outline, time required, materials, activities, and closure ideas for the lesson. The Classroom Connectors address content with an activity approach while incorporating themes necessary to raise the activity to a higher cognition level. The major motivation is to employ instructional strategies that bring the students physically and mentally into touch with the science they are studying.

  18. Corticotropin Releasing Factor in Neuroplasticity

    PubMed Central

    Regev, Limor; Baram, Tallie Z.

    2013-01-01

    Stress is among the strongest signals promoting neuroplasticity: Stress signals, indicating real or perceived danger, lead to alterations of neuronal function and often structure, designed to adapt to the changed conditions and promote survival. Corticotropin releasing factor (CRF) is expressed and released in several types of neuronal populations that are involved in cognition, emotion and the regulation of autonomic and endocrine function. CRF expressing neurons undergo functional and structural plasticity during stress and, in addition, the peptide acts via specific receptors to promote plasticity of target neurons. PMID:24145148

  19. Nucleon Form Factors from BLAST

    NASA Astrophysics Data System (ADS)

    Kohl, Michael

    2009-08-01

    The BLAST (Bates Large Acceptance Spectrometer Toroid) experiment has been carried out at the MIT-Bates Linear Accelerator Center to study spin-dependent electron scattering from protons and deuterons with small systematic uncertainties. The experiment used a longitudinally polarized, intense electron beam stored in the Bates South Hall Ring in combination with isotopically pure, highly-polarized internal targets of polarized hydrogen and vector- and tensor-polarized deuterium from an atomic beam source. The BLAST data have been used to extract precise results for the elastic form factor ratios GE/GM of the proton and the neutron at low momentum transfer.

  20. Nucleon Form Factors from BLAST

    SciTech Connect

    Kohl, Michael [Hampton University, Hampton, VA 23668, USA and Jefferson Lab, Newport News, VA 23606 (United States)

    2009-08-04

    The BLAST (Bates Large Acceptance Spectrometer Toroid) experiment has been carried out at the MIT-Bates Linear Accelerator Center to study spin-dependent electron scattering from protons and deuterons with small systematic uncertainties. The experiment used a longitudinally polarized, intense electron beam stored in the Bates South Hall Ring in combination with isotopically pure, highly-polarized internal targets of polarized hydrogen and vector- and tensor-polarized deuterium from an atomic beam source. The BLAST data have been used to extract precise results for the elastic form factor ratios G{sub E}/G{sub M} of the proton and the neutron at low momentum transfer.

  1. Taking the Error Term of the Factor Model into Account: The Factor Score Predictor Interval

    ERIC Educational Resources Information Center

    Beauducel, Andre

    2013-01-01

    The problem of factor score indeterminacy implies that the factor and the error scores cannot be completely disentangled in the factor model. It is therefore proposed to compute Harman's factor score predictor that contains an additive combination of factor and error variance. This additive combination is discussed in the framework of classical

  2. A Test for the Number of Factors in an Approximate Factor Model

    Microsoft Academic Search

    Gregory Connor; Robert A. Korajczyk

    1993-01-01

    An important issue in applications of multifactor models of asset returns is the appropriate number of factors. Most extant tests for the number of factors are valid only for strict factor models, in which diversifiable returns are uncorrelated across assets. In this paper, the authors develop a test statistic to determine the number of factors in an approximate factor model

  3. Comparison and performance of different sulphided Ti-loaded mesostructured silica-supported CoMo catalysts in deep HDS

    Microsoft Academic Search

    T. A. Zepeda

    2008-01-01

    Ti-loaded mesostructured silica materials (HMS, MCM-41 and SBA-15), with Si\\/Ti atomic ratio of 40, were used for the preparation of supported CoMo catalysts. The catalysts were tested in the reaction of HDS of 4,6-DMDBT carried out in a continuous-flow microreactor in the liquid-phase. The samples were characterized by DRS UV-Vis, XPS, Micro-Raman spectroscopy, SBET, XRD, TPR, FT-IR of adsorbed NO

  4. 1 Introduc~ao A Mec^anica Estatistica usa como premissas basicas o conhecimento de alguns detalhes mi-

    E-print Network

    Kik, Pieter

    a descric~ao de propriedades e fen^omenos em escala termodin^amica, como equac~oes de estadoiculas que formam um sistema pode mudar radi- calmente as propriedades termodin^amicas. Alem de abrir: Termodin^amica Neste capitulo nos nos preocuparemos em usar apenas conceitos e leis da Termodin^amica. O

  5. Salmonella-secreted Virulence Factors

    SciTech Connect

    Heffron, Fred; Niemann, George; Yoon, Hyunjin; Kidwai, Afshan S.; Brown, Roslyn N.; McDermott, Jason E.; Smith, Richard D.; Adkins, Joshua N.

    2011-05-01

    In this short review we discuss secreted virulence factors of Salmonella, which directly affect Salmonella interaction with its host. Salmonella secretes protein to subvert host defenses but also, as discussed, to reduce virulence thereby permitting the bacteria to persist longer and more successfully disperse. The type III secretion system (TTSS) is the best known and well studied of the mechanisms that enable secretion from the bacterial cytoplasm to the host cell cytoplasm. Other secretion systems include outer membrane vesicles, which are present in all Gram-negative bacteria examined to date, two-partner secretion, and type VI secretion will also be addressed. Excellent reviews of Salmonella secreted effectors have focused on themes such as actin rearrangements, vesicular trafficking, ubiquitination, and the activities of the virulence factors themselves. This short review is based on S. Typhimurium infection of mice because it is a model of typhoid like disease in humans. We have organized effectors in terms of events that happen during the infection cycle and how secreted effectors may be involved.

  6. Risk factors of ?-hydroxybutyrate overdosing.

    PubMed

    Korf, Dirk J; Nabben, Ton; Benschop, Annemieke; Ribbink, Kim; van Amsterdam, Jan G C

    2014-01-01

    The aim of this study was to identify in recreational drug users the factors which increase the risk of overdosing (OD) with ?-hydroxybutyrate (GHB). A purposive sample of 45 experienced GHB users was interviewed, equally divided into three groups (never OD, occasional OD, and repeat OD). The repeat OD group scored highest on many risk factors regarding GHB use, the occasional OD group scored intermediate, and the never OD group scored lowest. Participants, whether or not they had overdosed on GHB, most often perceived GHB use (e.g. using more GHB than usual, using GHB doses too closely together) as the main reason for GHB OD, and many participants who had overdosed on GHB reported that they had taken more GHB than usual at their most recent occasion of GHB OD. No significant differences in co-use of GHB with other substances were found between the three groups. Our findings indicate that using GHB in the company of groups of friends probably reduces, but does not eliminate, the risk of OD. PMID:24080792

  7. Environmental factors and allergic diseases.

    PubMed

    Jenerowicz, Dorota; Silny, Wojciech; Da?czak-Pazdrowska, Aleksandra; Pola?ska, Adriana; Osmola-Ma?kowska, Agnieszka; Olek-Hrab, Karolina

    2012-01-01

    An objective of this article is a review of contemporary knowledge on various environmental factors, that influence prevalence and course of allergic diseases, like asthma, allergic rhinitis, atopic dermatitis and also contact dermatitis. Surrounding climate may directly influence each patient, but also determines type of flora and fauna within particular geographical regions and thus affects sources of airborne and food allergens. Epidemiological studies suggest that there is a strong relationship between air pollution and development and exacerbation of asthma and other allergic diseases--main attention has been concentrated on gaseous materials such as ozone (O(3)) and nitrogen dioxide (NO(2)), as well as particulate matter (PM), generated by car traffic and industry. Diesel exhaust particulate (DEP) has the ability to bind proteins and may serve as a potential carrier of allergens, penetrating deep into respiratory tract. Among the most extensively studied environmental factors influencing allergy are airborne allergens: dust mites, pollens, fungi and animal dander. Foods may elicit both true IgE-mediated allergy and also various non-immunological reactions, associated with direct release of mediators or toxic activity. It has been estimated, that over 85,000 chemicals are recognized in the human environment and they may act as contact allergens or irritants, causing allergic or non-allergic contact dermatitis. Among them metals, fragrances, preservatives, botanicals and paraphenylenediamine are considered as the most significant. Infections have always been associated with etiopathogenesis of allergic diseases and they may contribute to exacerbation of their course. PMID:23020042

  8. Dissecting Soft Radiation with Factorization

    E-print Network

    Iain W. Stewart; Frank J. Tackmann; Wouter J. Waalewijn

    2015-02-10

    An essential part of high-energy hadronic collisions is the soft hadronic activity that underlies the primary hard interaction. It includes soft radiation from the primary hard partons, secondary multiple parton interactions (MPI), and factorization-violating effects. The invariant mass spectrum of the leading jet in $Z$+jet and $H$+jet events is directly sensitive to these effects, and we use a QCD factorization theorem to predict its dependence on the jet radius $R$, jet $p_T$, jet rapidity, and partonic process for both the perturbative and nonperturbative components of primary soft radiation. We prove that the nonperturbative contributions involve only odd powers of $R$, and the linear $R$ term is universal for quark and gluon jets. The hadronization model in PYTHIA8 agrees well with these properties. The perturbative soft initial state radiation (ISR) has a contribution that depends on the jet area in the same way as the underlying event, but this degeneracy is broken by dependence on the jet $p_T$. The size of this soft ISR contribution is proportional to the color state of the initial partons, yielding the same positive contribution for $gg\\to Hg$ and $gq\\to Zq$, but a negative interference contribution for $q\\bar q\\to Z g$. Hence, measuring these dependencies allows one to separate hadronization, soft ISR, and MPI contributions in the data.

  9. Factors influencing breath ammonia determination.

    PubMed

    Solga, Steven F; Mudalel, Matthew; Spacek, Lisa A; Lewicki, Rafal; Tittel, Frank; Loccioni, Claudio; Russo, Adolfo; Risby, Terence H

    2013-09-01

    Amongst volatile compounds (VCs) present in exhaled breath, ammonia has held great promise and yet it has confounded researchers due to its inherent reactivity. Herein we have evaluated various factors in both breath instrumentation and the breath collection process in an effort to reduce variability. We found that the temperature of breath sampler and breath sensor, mouth rinse pH, and mode of breathing to be important factors. The influence of the rinses is heavily dependent upon the pH of the rinse. The basic rinse (pH 8.0) caused a mean increase of the ammonia concentration by 410 221 ppb. The neutral rinse (pH 7.0), slightly acidic rinse (pH 5.8), and acidic rinse (pH 2.5) caused a mean decrease of the ammonia concentration by 498 355 ppb, 527 198 ppb, and 596 385 ppb, respectively. Mode of breathing (mouth-open versus mouth-closed) demonstrated itself to have a large impact on the rate of recovery of breath ammonia after a water rinse. Within 30min, breath ammonia returned to 98 16% that of the baseline with mouth open breathing, while mouth closed breathing allowed breath ammonia to return to 53 14% of baseline. These results contribute to a growing body of literature that will improve reproducibly in ammonia and other VCs. PMID:23774041

  10. A Computer Program to Relate Factors Across Separately Factor Analyzed Variable Domains

    ERIC Educational Resources Information Center

    Morris, John D.; Guertin, Wilson H.

    1976-01-01

    A Fortran IV program is presented which will cross-correlate least squares estimated factor scores across separately factor analyzed variable domains without the tedious necessity of actually calculating the factor scores. (RC)

  11. 23 CFR 650.707 - Rating factor.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS BRIDGES, STRUCTURES, AND HYDRAULICS Discretionary Bridge Candidate Rating Factor 650.707 Rating factor. (a) The following formula is to be...

  12. 23 CFR 650.707 - Rating factor.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS BRIDGES, STRUCTURES, AND HYDRAULICS Discretionary Bridge Candidate Rating Factor 650.707 Rating factor. (a) The following formula is to be...

  13. 23 CFR 650.707 - Rating factor.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS BRIDGES, STRUCTURES, AND HYDRAULICS Discretionary Bridge Candidate Rating Factor 650.707 Rating factor. (a) The following formula is to be...

  14. 23 CFR 650.707 - Rating factor.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS BRIDGES, STRUCTURES, AND HYDRAULICS Discretionary Bridge Candidate Rating Factor 650.707 Rating factor. (a) The following formula is to be...

  15. Localized shrinkage factors and minimax results

    NASA Technical Reports Server (NTRS)

    Kostal, H.

    1983-01-01

    A condition is derived under which a localized shrinkage factor estimator will be minimax. A specific localized shrinkage factor estimator is described. The nonapplicability of the derived condition to some estimators is shown. Several comments concerning these results are made.

  16. Mathematics of the ShearWarp Factorization

    E-print Network

    Stanford University

    is to factor an arbitrary affine viewing transformation matrix M view as follows: M view = Mwarp \\Delta M shear M shear is a shear matrix and Mwarp is an affine transformation matrix. The matrix factors must

  17. Cone Penetrometer N Factor Determination Testing Results

    SciTech Connect

    Follett, Jordan R.

    2014-03-05

    This document contains the results of testing activities to determine the empirical 'N Factor' for the cone penetrometer in kaolin clay simulant. The N Factor is used to releate resistance measurements taken with the cone penetrometer to shear strength.

  18. Crop Management Factors: What is Important?

    E-print Network

    Kastens, Terry L.; Dhuyvetter, Kevin C.; Nivens, Heather; Klinefelter, Danny A.

    1999-09-29

    Various management factors, including specific practices and the persistence of those practices over time, can greatly influence farm profitability. Some of those factors are managing for high yield or low production cost, as well as adoption...

  19. Is Human Factors Engineering Worth the Investment?

    Microsoft Academic Search

    Kenneth S. Teel

    1971-01-01

    The cost of and the savings resulting from three different human factors engineering studies are presented. The data cited indicate clearly that human factors work can be highly cost effective and yield high returns on investment.

  20. 14 CFR 460.15 - Human factors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...2010-01-01 2010-01-01 false Human factors. 460.15 Section 460...DEPARTMENT OF TRANSPORTATION LICENSING HUMAN SPACE FLIGHT REQUIREMENTS Launch and Reentry with Crew 460.15 Human factors. An operator must take...

  1. Human Factors in Intelligence, Surveillance, and Reconnaissance

    E-print Network

    Preece, Alun

    Human Factors in Intelligence, Surveillance, and Reconnaissance: Gaps for Soldiers and Technology Recommendations Jonathan Z. Bakdash Human Research and Engineering Directorate U.S. Army Research Laboratory gaps, we use approaches from Human Factors (interactions between humans and technical systems

  2. ARITHMETIC PROGRESSIONS IN A UNIQUE FACTORIZATION DOMAIN

    E-print Network

    Ghorpade, Sudhir

    ARITHMETIC PROGRESSIONS IN A UNIQUE FACTORIZATION DOMAIN. We give a new proof of a slight generalization of this result to arithmetic progressions of integers and further extend it to arithmetic progressions in unique factorization domains

  3. EXPOSURE FACTORS HANDBOOK (EXTERNAL REVIEW DRAFT) 1996

    EPA Science Inventory

    This handbook provided a summary of the available statistical data on various factors used in assessing human exposure. Volume I, General Factors, includes an introduction and discussion of uncertainty and provides data for drinking water consumption, soil ingestion, inha...

  4. 40 CFR 1033.245 - Deterioration factors.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...than locomotive-to-locomotive variability. Multiplicative deterioration factors must be specified to one more significant figure than the applicable standard. (c) Deterioration factors for smoke are always additive. (d) If...

  5. 40 CFR 1033.245 - Deterioration factors.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...than locomotive-to-locomotive variability. Multiplicative deterioration factors must be specified to one more significant figure than the applicable standard. (c) Deterioration factors for smoke are always additive. (d) If...

  6. 40 CFR 1033.245 - Deterioration factors.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...than locomotive-to-locomotive variability. Multiplicative deterioration factors must be specified to one more significant figure than the applicable standard. (c) Deterioration factors for smoke are always additive. (d) If...

  7. 23 CFR 650.707 - Rating factor.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS BRIDGES, STRUCTURES, AND HYDRAULICS Discretionary Bridge Candidate Rating Factor 650.707 Rating factor. (a) The following formula is to be...

  8. The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

    Microsoft Academic Search

    David W. Banner; Allan D'Arcy; Christiana Chne; Fritz K. Winkler; Arabinda Guha; William H. Konigsberg; Yale Nemerson; Daniel Kirchhofer

    1996-01-01

    Blood coagulation is initiated when tissue factor binds to coagulation factor Vila to give an enzymatically active complex which then activates factors IX and X, leading to thrombin generation and clot formation. We have determined the crystal structure at 2.0- resolution of active-site-inhibited factor VIIa complexed with the cleaved extracellular domain of tissue factor. In the complex, factor VIIa adopts

  9. Trophic factors and central nervous system metastasis

    Microsoft Academic Search

    Garth L. Nicolson; David G. Menter

    1995-01-01

    To metastasize to the central nervous system (CNS) malignant cells must attach to brain microvessel endothelial cells, respond to brain endothelial cell-derived motility factors, respond to CNS-derived invasion factors and invade the blood-brain barrier (BBB), and finally, respond to CNS survival and growth factors. Trophic factors such as the neurotrophins play an important role in tumor cell invasion into the

  10. Characterization of a cancer cachectic factor

    Microsoft Academic Search

    Penio Todorov; Peter Cariuk; Trudi McDevitt; Brian Coles; Kenneth Fearon; Michael Tisdale

    1996-01-01

    CANCER cachexia is a syndrome of progressive wasting which has been suggested to be mediated by tumour-necrosis factor-alpha (ref. 1), interleukins 1 and 6 (ref. 2), interferon-gamma (ref. 3) and leukaemia-inhibitory factor4. It has proved difficult to correlate levels of tumour-necrosis factor-alpha and interleukin-6 with cancer cachexia5,6, and the weight loss induced by leukaemia-inhibitory factor may be due to toxicity7.

  11. The ?P transition form factors in QCD

    NASA Astrophysics Data System (ADS)

    Kroll, P.

    2012-04-01

    In an analysis by Kroll (2011) [11] the form factors for the transitions from a photon to a pseudoscalar meson P=?0,?,??,?c within QCD are reported. The sharp rise of the ?? form factor with the photon virtuality demands strong power corrections to the results from collinear factorization in contrast to the other transition form factors. The power corrections are modeled as quark transverse momenta accompanied by gluon radiation.

  12. The pH Factor

    NSDL National Science Digital Library

    The Miami Museum of Science's learning site, The pH Factor, gives teachers a fun and interactive way to teach elementary and middle school students some basics of science. Material is divided into seven learning areas: excite, explore, explain, expand, extend, exchange, and examine. Each contains an interactive screen that can be used directly in the classroom and lesson plans that correspond with each subject. For example, the excite area contains the "tasting tongue" that, when clicked, shows the location on the tongue where you taste bitter or sour things. The site's teaching style is based on the proposition that learners need to build their own understanding of new ideas. The unique material that is offered on this site provides educators with an excellent alternative for teaching these sometimes difficult concepts to grade school students.

  13. Associated factors of protracted diarrhea.

    PubMed

    Khoshoo, V; Bhan, M K

    1990-06-01

    The associated factors in 80 children (less than 2 yrs) with protracted diarrhea (greater than 21 days duration) and weight loss were: secondary carbohydrate intolerance (36): enteric pathogens (non typhoidal salmonella (11), enteropathogenic E. coli 'EPEC' (6), giardia (4), and shigella (3); cow's milk protein intolerance (3), gluten intolerance (3); miscellaneous (5); and undiagnosed enteropathy (9). Three of the EPEC showed localised pattern of adherence in vitro with HEP-2 cells. Most patients with salmonella and EPEC had severe secretory diarrhea with large fecal sodium losses. All 6 patients who died had secretory diarrhea and very high fecal sodium. All but 4 patients could be effectively managed with a chicken puree-glucose-coconut oil based diet. PMID:2253991

  14. Manned Mars mission crew factors

    NASA Technical Reports Server (NTRS)

    Santy, Patricia A.

    1986-01-01

    Crew factors include a wide range of concerns relating to the human system and its role in a Mars mission. There are two important areas which will play a large part in determining the crew for a Mars mission. The first relates to the goals and priorities determined for such a vast endeavor. The second is the design of the vehicle for the journey. The human system cannot be separated from the other systems in that vehicle. In fact it will be the human system which drives the development of many of the technical breakthroughs necessary to make a Mars mission successful. As much as possible, the engineering systems must adapt to the needs of the human system and its individual components.

  15. Factors for Bioenergy Market Development

    SciTech Connect

    Roos, A.; Hektor, B.; Graham, R.L.; Rakos, C.

    1998-10-04

    Focusing on the development of the whole bioenergy market rather than isolated projects, this paper contributes to the identification of barriers and drivers behind bioenergy technology implementation. It presents a framework for the assessment of the potentials for bioenergy market growth to be used by decision makers in administration and industry. The conclusions are based on case studies of operating bioenergy markets in Austria, US and Sweden. Six important factors for bioenergy market growth have been identified: (1) Integration with other business, e.g. for biomass procurement, (2) Scale effects of bioenergy market, (3) Competition on bioenergy market, (4) Competition with other business, (5) National policy, (6) Local policy and local opinion. Different applications of the framework are discussed.

  16. Form factors from lattice QCD

    SciTech Connect

    Dru Renner

    2012-04-01

    Precision computation of hadronic physics with lattice QCD is becoming feasible. The last decade has seen precent-level calculations of many simple properties of mesons, and the last few years have seen calculations of baryon masses, including the nucleon mass, accurate to a few percent. As computational power increases and algorithms advance, the precise calculation of a variety of more demanding hadronic properties will become realistic. With this in mind, I discuss the current lattice QCD calculations of generalized parton distributions with an emphasis on the prospects for well-controlled calculations for these observables as well. I will do this by way of several examples: the pion and nucleon form factors and moments of the nucleon parton and generalized-parton distributions.

  17. Language deficits and genetic factors.

    PubMed

    Gopnik, M

    1997-04-01

    Although most children acquire language effortlessly, there are some children who find learning language a difficult and arduous task. This group of subjects resembles a natural experiment and has the potential to provide us with insights into the nature of the biological basis of language. The data show that this disorder is associated with certain genetic factors that can lead to neurological abnormalities. Our studies of the linguistic details of language impairment in English, French, Greek and Japanese have led us to conclude that affected individuals cannot construct normal representations for complex words nor can they construct the rules which should operate on these representations. These data are inconsistent with any explanation in terms of auditory or articulatory processing. Therefore, we must conclude that a genetic disorder can impair the ability to build a normal grammar. PMID:21223846

  18. Term Structure Dynamics with Macroeconomic Factors

    E-print Network

    Park, Ha-Il

    2011-02-22

    specifications, and the number of latent factors. Next, I incorporate latent macro factors and the spread factor between the short-term Treasury yield and the federal funds rate into an affine term structure model by imposing cross-equation restrictions from no...

  19. 14 CFR 23.623 - Bearing factors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...2014-01-01 2014-01-01 false Bearing factors. 23.623 Section 23.623...Design and Construction 23.623 Bearing factors. (a) Each part that has...to pounding or vibration, must have a bearing factor large enough to provide for...

  20. 14 CFR 23.623 - Bearing factors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...2010-01-01 2010-01-01 false Bearing factors. 23.623 Section 23.623...Design and Construction 23.623 Bearing factors. (a) Each part that has...to pounding or vibration, must have a bearing factor large enough to provide for...

  1. 14 CFR 27.623 - Bearing factors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...2012-01-01 2012-01-01 false Bearing factors. 27.623 Section 27.623...Construction General 27.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  2. 14 CFR 27.623 - Bearing factors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...2011-01-01 2011-01-01 false Bearing factors. 27.623 Section 27.623...Construction General 27.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  3. 14 CFR 29.623 - Bearing factors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...2010-01-01 2010-01-01 false Bearing factors. 29.623 Section 29.623...Construction General 29.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  4. 14 CFR 23.623 - Bearing factors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...2012-01-01 2012-01-01 false Bearing factors. 23.623 Section 23.623...Design and Construction 23.623 Bearing factors. (a) Each part that has...to pounding or vibration, must have a bearing factor large enough to provide for...

  5. 14 CFR 29.623 - Bearing factors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...2012-01-01 2012-01-01 false Bearing factors. 29.623 Section 29.623...Construction General 29.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  6. 14 CFR 29.623 - Bearing factors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...2011-01-01 2011-01-01 false Bearing factors. 29.623 Section 29.623...Construction General 29.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  7. 14 CFR 23.623 - Bearing factors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...2011-01-01 2011-01-01 false Bearing factors. 23.623 Section 23.623...Design and Construction 23.623 Bearing factors. (a) Each part that has...to pounding or vibration, must have a bearing factor large enough to provide for...

  8. 14 CFR 25.623 - Bearing factors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...2013-01-01 2013-01-01 false Bearing factors. 25.623 Section 25.623...Construction General 25.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  9. 14 CFR 29.623 - Bearing factors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...2013-01-01 2013-01-01 false Bearing factors. 29.623 Section 29.623...Construction General 29.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  10. 14 CFR 25.623 - Bearing factors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...2012-01-01 2012-01-01 false Bearing factors. 25.623 Section 25.623...Construction General 25.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  11. 14 CFR 25.623 - Bearing factors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...2010-01-01 2010-01-01 false Bearing factors. 25.623 Section 25.623...Construction General 25.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  12. 14 CFR 29.623 - Bearing factors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...2014-01-01 2014-01-01 false Bearing factors. 29.623 Section 29.623...Construction General 29.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  13. 14 CFR 27.623 - Bearing factors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...2013-01-01 2013-01-01 false Bearing factors. 27.623 Section 27.623...Construction General 27.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  14. 14 CFR 27.623 - Bearing factors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...2014-01-01 2014-01-01 false Bearing factors. 27.623 Section 27.623...Construction General 27.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  15. 14 CFR 23.623 - Bearing factors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...2013-01-01 2013-01-01 false Bearing factors. 23.623 Section 23.623...Design and Construction 23.623 Bearing factors. (a) Each part that has...to pounding or vibration, must have a bearing factor large enough to provide for...

  16. 14 CFR 27.623 - Bearing factors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...2010-01-01 2010-01-01 false Bearing factors. 27.623 Section 27.623...Construction General 27.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  17. 14 CFR 25.623 - Bearing factors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...2014-01-01 2014-01-01 false Bearing factors. 25.623 Section 25.623...Construction General 25.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  18. 14 CFR 25.623 - Bearing factors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...2011-01-01 2011-01-01 false Bearing factors. 25.623 Section 25.623...Construction General 25.623 Bearing factors. (a) Except as provided...to pounding or vibration, must have a bearing factor large enough to provide for...

  19. Comparing Factor Structures of Adolescent Psychopathology

    ERIC Educational Resources Information Center

    Verona, Edelyn; Javdani, Shabnam; Sprague, Jenessa

    2011-01-01

    Research on the structure of adolescent psychopathology can provide information on broad factors that underlie different forms of maladjustment in youths. Multiple studies from the literature on adult populations suggest that 2 factors, Internalizing and Externalizing, meaningfully comprise the factor structure of adult psychopathology (e.g.,

  20. Hierarchical Factoring in a Standardized Achievement Battery.

    ERIC Educational Resources Information Center

    Martin, David J.; Dunbar, Stephen B.

    1985-01-01

    The factorial validity of the Iowa Tests of Basic Skills was investigated. Hierarchical factor analysis was performed with a subset of the standardization data to explore the presence of second-order group factors. Results supported the construct validity of Language and Mathematics subscales. Verbal and Visual Information group factors were

  1. Prime Factorization in the Duality Computer

    E-print Network

    Wan-Ying Wang; Bin Shang; Chuan Wang; Gui Lu Long

    2006-07-04

    We give algorithms to factorize large integers in the duality computer. We provide three duality algorithms for factorization based on a naive factorization method, the Shor algorithm in quantum computing, and the Fermat's method in classical computing. All these algorithms are polynomial in the input size.

  2. A Kilobit Special Number Field Sieve Factorization

    E-print Network

    Lenstra, Arjen K.

    A Kilobit Special Number Field Sieve Factorization Kazumaro Aoki1 , Jens Franke2 , Thorsten special number field sieve factorization of a number having more than 1024 bits, namely the Mersenne number 21039 - 1. Although this factorization is orders of magnitude `easier' than a fac- torization

  3. Determining the number of interpretable factors

    Microsoft Academic Search

    Charles B. Crawford

    1975-01-01

    Argues that a major weakness of current methods of determining the number of factors is that they require this decision to be made before rotation; therefore, information on the possible interpretability of factors cannot be considered in determining the appropriate number. An objective, noninferential index for determining the number of interpretable factors is described. The effects of type of rotation,

  4. Mac Lane and Factorization Walter Tholen

    E-print Network

    Tholen, Walter

    Mac Lane and Factorization Walter Tholen York University, Toronto June 15, 2006 Walter Tholen (York University, Toronto) Mac Lane and Factorization CT2006 1 / 31 #12;Walter Tholen (York University, Toronto) Mac Lane and Factorization CT2006 2 / 31 #12;Saunders Mac Lane Duality for groups Bulletin

  5. Journal influence factors6 Massimo Franceschet

    E-print Network

    Franceschet, Massimo

    Journal influence factors6 Massimo Franceschet Department of Mathematics and Computer Science of journal influence, namely 2- year impact factor, 5-year impact factor, eigenfactor and article influence. These indicators have been recently added by Thomson Reuters to the Journal Citation Reports, in both science

  6. Infrared Scales and Factorization in QCD

    E-print Network

    Aneesh V. Manohar

    2005-12-14

    Effective field theory methods are used to study factorization of the deep inelastic scattering cross-section. The cross-section is shown to factor in QCD, even though it does not factor in perturbation theory for some choices of the infrared regulator. Messenger modes are not required in soft-collinear effective theory for deep inelastic scattering as x -> 1.

  7. Shor Factorization Algorithm Robert B. Griffiths

    E-print Network

    Griffiths, Robert B.

    qitd512 Shor Factorization Algorithm Robert B. Griffiths Version of 7 March 2012 References: Mermin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 5 Post-Processing: Continued Fractions 6 1 Introduction Shor's algorithm for factoring numbers elements of Z 15? The strategy employed by Shor to factor N begins with the observation that that if one

  8. Human factors: a necessary tool for industry

    SciTech Connect

    Starcher, K.O.

    1984-03-09

    The need for human factors (ergonomics) input in the layout of a ferroelectric ceramics laboratory is presented as an example of the overall need for human factors professionals in industry. However, even in the absence of one trained in human factors, knowledge of a few principles in ergonomics will provide many possibilities for improving performance in the industrial environment.

  9. Kinematically covariant calculation of meson form factors

    Microsoft Academic Search

    A. Ilakovac; D. Tadic

    1991-01-01

    Hadron form factors are calculated in the relativized version of the MIT bag model. The model, without any additional fitting parameters, gives acceptable values for proton and pion electromagnetic form factors. Theoretical predictions for K-, D-, and B-meson form factors are compared with other theoretical results and with the experimental data for semileptonic decays.

  10. Rainbow H-factors Raphael Yuster

    E-print Network

    Yuster, Raphael

    Rainbow H-factors Raphael Yuster Department of Mathematics University of Haifa, Haifa 31905, Israel, a rainbow H-subgraph of G is an H-subgraph of G whose edges have distinct colors. A rainbow H-factor is an H-factor whose components are rainbow H-subgraphs. The follow- ing result is proved. If H is any fixed graph

  11. INNOVATION FACTORS IN BELGRADE UNIVERSITY LIBRARY SYSTEM

    Microsoft Academic Search

    BILJANA STOSIC; ADAM SOFRONIJEVIC

    2011-01-01

    The aim of this paper is to present research shedding some light on innovation factors identification and measurement in the University of Belgrades library system by means of innovation questionnaire, since one of the main innovation management elements is to recognize and measure innovation factors of influence. In that sense, the key innovation factors important for this domain have been

  12. Age Learning Factors Affecting Pilot Education.

    ERIC Educational Resources Information Center

    Torbert, Brison

    This document, intended for pilot education and flight safety specialists, consists chiefly of a review of the literature on physiological factors that affect pilot education and an examination of environmental factors that should be scrutinized in order to improve the effectiveness of aviation learning facilities. The physiological factors

  13. NASA Technical Memorandum Aviation Human Factors

    E-print Network

    NASA Technical Memorandum Aviation Human Factors Research in U.S. Universities: Potential #12;1 Aviation Human Factors Research in U.S. Universities: Potential Contributions to National Needs contributions to national needs in aviation human factors. However, to guide and utilize university research

  14. RSA Cryptography: Factorization 1 Background 2

    E-print Network

    Stein, William

    RSA Cryptography: Factorization Kevin Chu 3/11/10 Contents 1 Background 2 1.1 What is RSA . . . . . . . . . . . . . . . . . . . . . 4 3.2 Elliptic curve factorization . . . . . . . . . . . . . . . . . . . . 5 4 Alternatives to RSA? 5 1 #12;Abstract The purpose of this paper is to explore the topic of factorization in RSA

  15. EXPOSURE FACTORS HANDBOOK (1997 FINAL REPORT)

    EPA Science Inventory

    The Exposure Factors Handbook provides a summary of the available statistical data on various factors used in assessing human exposure. This Handbook is addressed to exposure assessors inside the Agency as well as outside, who need to obtain data on standard factors to calculate ...

  16. Factors Impacting the Child with Behavioral Inhibition

    ERIC Educational Resources Information Center

    Hornbuckle, Suzanne R.

    2010-01-01

    Various factors influence the developmental course of the behaviorally inhibited child. These factors include reciprocating, contextual factors, such as the child's own traits, the environment, the maternal characteristics, and the environment. Behaviorally inhibited children show physiological and behavioral signs of fear and anxiety when

  17. 40 CFR 227.15 - Factors considered.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 2011-07-01 false Factors considered. 227.15 Section...Ocean Dumping 227.15 Factors considered. The need for...evaluation of the following factors: (a) Degree of treatment...relative environmental risks, impact and cost for ocean...

  18. 40 CFR 227.15 - Factors considered.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2010-07-01 false Factors considered. 227.15 Section...Ocean Dumping 227.15 Factors considered. The need for...evaluation of the following factors: (a) Degree of treatment...relative environmental risks, impact and cost for ocean...

  19. The meaning of the Impact Factor

    Microsoft Academic Search

    E. Garfield

    2003-01-01

    ABSTRACT The impact factor and other bibliometric indicators are currently utilized in most countries to evaluate institutions, scientific research, entire journals, and indi - vidual articles This article addresses some of the most frequently asked questions about the impact factor and its application The impact factor's origin and methods of calculating it are examined Also, discussed are the effects of

  20. 40 CFR 227.15 - Factors considered.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2011-07-01 true Factors considered. 227.15 Section...Ocean Dumping 227.15 Factors considered. The need for...evaluation of the following factors: (a) Degree of treatment...relative environmental risks, impact and cost for ocean...

  1. 40 CFR 227.15 - Factors considered.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 false Factors considered. 227.15 Section...Ocean Dumping 227.15 Factors considered. The need for...evaluation of the following factors: (a) Degree of treatment...relative environmental risks, impact and cost for ocean...

  2. Design Guest Editorial On Journal Impact Factors

    E-print Network

    Papalambros, Panos

    Journal of Mechanical Design Guest Editorial On Journal Impact Factors How good is the Journal numerical "journal impact factors." As engineers, quantification is attractive to us; but as with any Division. I asked Shapour to contrib- ute this guest editorial on journal impact factors, and I am very

  3. Convex-dense Bivariate Polynomial Factorization

    E-print Network

    Paris-Sud XI, Universit de

    over K that we want to factor. At the present time, the best known complexity bounds for the squarefree and irreducible factorization problems are essentially obtained in terms of the dense size of F. This is relevant complexity result on support reduction, and then corollaries on factorizations. 1.1. Sizes of polynomials

  4. THE STRUCTURE OF FACTOR ORACLES MAXIME CROCHEMORE

    E-print Network

    Boyer, Edmond

    introduce a framework where various oracles can be compared. The factor oracle is better than several of a string the factor oracle is a particular case here and build a framework for comparing such oraclesTHE STRUCTURE OF FACTOR ORACLES MAXIME CROCHEMORE Institut Gaspard-Monge, Universite de Marne

  5. The Infinitesimal Jackknife with Exploratory Factor Analysis

    ERIC Educational Resources Information Center

    Zhang, Guangjian; Preacher, Kristopher J.; Jennrich, Robert I.

    2012-01-01

    The infinitesimal jackknife, a nonparametric method for estimating standard errors, has been used to obtain standard error estimates in covariance structure analysis. In this article, we adapt it for obtaining standard errors for rotated factor loadings and factor correlations in exploratory factor analysis with sample correlation matrices. Both

  6. 14 CFR 31.43 - Fitting factor.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...Design Construction 31.43 Fitting factor. (a) A fitting factor of at least 1.15 must be used in the analysis of each fitting the strength of...fitting and surrounding structure. This factor applies to all parts of the...

  7. 14 CFR 29.625 - Fitting factors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...members. (b) No fitting factor need be used (1...for which a larger special factor is used. (c) For each...structure must be shown by analysis, tests, or both, to be...3) multiplied by a fitting factor of 1.33. [Doc....

  8. 14 CFR 27.625 - Fitting factors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...members. (b) No fitting factor need be used (1...for which a larger special factor is used. (c) For each...structure must be shown by analysis, tests, or both, to be...3) multiplied by a fitting factor of 1.33. [Doc....

  9. 14 CFR 23.625 - Fitting factors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...surrounding structures, a fitting factor of at least 1.15 must be applied...members. (b) No fitting factor need be used for joint designs...structure must be shown, by analysis, tests, or both, to be able...561 multiplied by a fitting factor of 1.33. [Doc....

  10. 14 CFR 23.625 - Fitting factors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...surrounding structures, a fitting factor of at least 1.15 must be applied...members. (b) No fitting factor need be used for joint designs...structure must be shown, by analysis, tests, or both, to be able...561 multiplied by a fitting factor of 1.33. [Doc....

  11. 14 CFR 29.625 - Fitting factors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...members. (b) No fitting factor need be used (1...for which a larger special factor is used. (c) For each...structure must be shown by analysis, tests, or both, to be...3) multiplied by a fitting factor of 1.33. [Doc....

  12. The Factor Game (i-Math Investigations)

    NSDL National Science Digital Library

    Math Forum

    2001-01-01

    An online, interactive, multimedia math investigation. The Factor Game engages students in a friendly contest in which winning strategies involve distinguishing between numbers with many factors and numbers with few factors. Students are then guided through an analysis of game strategies and introduced to the definitions of prime and composite numbers.

  13. 14 CFR 31.43 - Fitting factor.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...Design Construction 31.43 Fitting factor. (a) A fitting factor of at least 1.15 must be used in the analysis of each fitting the strength of...fitting and surrounding structure. This factor applies to all parts of the...

  14. Measurement Bias Detection through Factor Analysis

    ERIC Educational Resources Information Center

    Barendse, M. T.; Oort, F. J.; Werner, C. S.; Ligtvoet, R.; Schermelleh-Engel, K.

    2012-01-01

    Measurement bias is defined as a violation of measurement invariance, which can be investigated through multigroup factor analysis (MGFA), by testing across-group differences in intercepts (uniform bias) and factor loadings (nonuniform bias). Restricted factor analysis (RFA) can also be used to detect measurement bias. To also enable nonuniform

  15. 14 CFR 27.625 - Fitting factors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...members. (b) No fitting factor need be used (1...for which a larger special factor is used. (c) For each...structure must be shown by analysis, tests, or both, to be...3) multiplied by a fitting factor of 1.33. [Doc....

  16. Review of critical factors for SEA implementation

    SciTech Connect

    Zhang Jie, E-mail: jasmine@plan.aau.dk; Christensen, Per; Kornov, Lone

    2013-01-15

    The implementation process involved in translating Strategic Environmental Assessment (SEA) intention into action is vital to an effective SEA. Many factors influence implementation and thus the effectiveness of an SEA. Empirical studies have identified and documented some factors influencing the implementation of an SEA. This research is fragmented, however, and it is still not clear what are the most critical factors of effective SEA performance, and how these relate to different stages of the implementation process or other contextual circumstances. The paper takes its point of departure in implementation theory. Firstly, we introduce implementation theory, and then use it in practice to establish a more comprehensive model related to the stages in the implementation process. Secondly, we identify the critical factors in order to see how they are related to the different stages of SEA or are more general in character. Finally we map the different critical factors and how they influence the overall results of an SEA. Based on a literature review, we present a comprehensive picture of the critical factors and where they are found in the process. We conclude that most of the critical factors identified are of a more general character influencing the SEA process as such, while only one out of four of these factors relates to the specific stages of the SEA. Based on this mapping we can sketch a picture of the totality of critical factors. In this study 266 notions of critical factors were identified. Seen at the level of notions of critical factors, only 24% of these relate to specific stages while for 76% the critical factors are of a more general nature. These critical factors interact in complex ways and appear in different combinations in different stages of the implementation process so tracing the cause and effect is difficult. The pervasiveness of contextual and general factors also clearly suggests that there is no single way to put SEA into practice. The paper identifies some of the critical factors for effective SEA implementation, but further research is still needed to conclude which factors are more critical than others, just as the contingencies on which they depend are not easy to unravel. - Highlights: Black-Right-Pointing-Pointer The research on critical factors influencing SEA implementation is fragmented. Black-Right-Pointing-Pointer The critical factors are used to discuss 'hot-spots' in the implementation process. Black-Right-Pointing-Pointer Critical factors are just as broad as the concept of effectiveness. Black-Right-Pointing-Pointer Both stage and general factors are relevant in explaining the effectiveness of SEA.

  17. Factorization using the quadratic sieve algorithm

    SciTech Connect

    Davis, J.A.; Holdridge, D.B.

    1983-01-01

    Since the cryptosecurity of the RSA two key cryptoalgorithm is no greater than the difficulty of factoring the modulus (product of two secret primes), a code that implements the Quadratic Sieve factorization algorithm on the CRAY I computer has been developed at the Sandia National Laboratories to determine as sharply as possible the current state-of-the-art in factoring. Because all viable attacks on RSA thus far proposed are equivalent to factorization of the modulus, sharper bounds on the computational difficulty of factoring permit improved estimates for the size of RSA parameters needed for given levels of cryptosecurity. Analysis of the Quadratic Sieve indicates that it may be faster than any previously published general purpose algorithm for factoring large integers. The high speed of the CRAY I coupled with the capability of the CRAY to pipeline certain vectorized operations make this algorithm (and code) the front runner in current factoring techniques.

  18. Factorization using the quadratic sieve algorithm

    SciTech Connect

    Davis, J.A.; Holdridge, D.B.

    1983-12-01

    Since the cryptosecurity of the RSA two key cryptoalgorithm is no greater than the difficulty of factoring the modulus (product of two secret primes), a code that implements the Quadratic Sieve factorization algorithm on the CRAY I computer has been developed at the Sandia National Laboratories to determine as sharply as possible the current state-of-the-art in factoring. Because all viable attacks on RSA thus far proposed are equivalent to factorization of the modulus, sharper bounds on the computational difficulty of factoring permit improved estimates for the size of RSA parameters needed for given levels of cryptosecurity. Analysis of the Quadratic Sieve indicates that it may be faster than any previously published general purpose algorithm for factoring large integers. The high speed of the CRAY I coupled with the capability of the CRAY to pipeline certain vectorized operations make this algorithm (and code) the front runner in current factoring techniques.

  19. Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex

    SciTech Connect

    Chi Ki Ngo,J.; Huang, M.; Roth, D.; Furie, B.; Furie, B.

    2008-01-01

    Factor VIII is a procofactor that plays a critical role in blood coagulation, and is missing or defective in hemophilia A. We determined the X-ray crystal structure of B domain-deleted human factor VIII. This protein is composed of five globular domains and contains one Ca(2+) and two Cu(2+) ions. The three homologous A domains form a triangular heterotrimer where the A1 and A3 domains serve as the base and interact with the C2 and C1 domains, respectively. The structurally homologous C1 and C2 domains reveal membrane binding features. Based on biochemical studies, a model of the factor IXa-factor VIIIa complex was constructed by in silico docking. Factor IXa wraps across the side of factor VIII, and an extended interface spans the factor VIII heavy and light chains. This model provides insight into the activation of factor VIII and the interaction of factor VIIIa with factor IXa on the membrane surface.

  20. Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex

    SciTech Connect

    Ngo, J.C.; Huang, M.; Roth, D.A.; Furie, B.C.; Furie, B. (Wyeth); (MBL)

    2008-06-03

    Factor VIII is a procofactor that plays a critical role in blood coagulation, and is missing or defective in hemophilia A. We determined the X-ray crystal structure of B domain-deleted human factor VIII. This protein is composed of five globular domains and contains one Ca{sup 2+} and two Cu{sup 2+} ions. The three homologous A domains form a triangular heterotrimer where the A1 and A3 domains serve as the base and interact with the C2 and C1 domains, respectively. The structurally homologous C1 and C2 domains reveal membrane binding features. Based on biochemical studies, a model of the factor IXa-factor VIIIa complex was constructed by in silico docking. Factor IXa wraps across the side of factor VIII, and an extended interface spans the factor VIII heavy and light chains. This model provides insight into the activation of factor VIII and the interaction of factor VIIIa with factor IXa on the membrane surface.

  1. Estudio de NIH indica que la actividad fsica en tiempo libre alarga la vida tanto como 4,5 aos

    Cancer.gov

    La actividad fsica en tiempo libre est asociada con una expectativa de vida ms larga, aun en un grado de actividad relativamente bajo e independientemente del peso corporal, de acuerdo con un estudio llevado a cabo por un equipo de investigadores del Instituto Nacional del Cncer (NCI), el cual forma parte de los Institutos Nacionales de la Salud, (NIH). El estudio, el cual encontr que las personas que realizaron actividad fsica en tiempo libre ganaron en su expectativa de vida tanto como 4,5 aos, se public el 6 de noviembre de 2012, en la revista PloS Medicine.

  2. Noniterative estimation and the choice of the number of factors in exploratory factor analysis

    Microsoft Academic Search

    Yutaka Kano

    1990-01-01

    Based on the usual factor analysis model, this paper investigates the relationship between improper solutions and the number of factors, and discusses the properties of the noniterative estimation method of Ihara and Kano in exploratory factor analysis. The consistency of the Ihara and Kano estimator is shown to hold even for an overestimated number of factors, which provides a theoretical

  3. Background Bayes Factor Simulation Study BF And PPP Using Bayes Factors for Model Selection in

    E-print Network

    Wolfe, Patrick J.

    Background Bayes Factor Simulation Study BF And PPP Using Bayes Factors for Model Selection in High-Energy Astrophysics Shandong Zhao Department of Statistic, UCI April, 2013 #12;Background Bayes Factor Simulation" to formally compare or select a model. #12;Background Bayes Factor Simulation Study BF And PPP Spectral

  4. Factor Analysis for Skewed Data and Skew-Normal Maximum Likelihood Factor Analysis

    E-print Network

    Gaucher, Beverly Jane

    2013-04-04

    . . . . . . . . . . . . . . 33 2.11 Review of Selected Literature for Non-Normal Factor Analysis . . 34 2.11.1 Factor Analysis for Non-Normally Distributed Data . . . . 34 2.11.2 The Skew-Normal Factor Model . . . . . . . . . . . . . . . 41 3. FACTOR ANALYSIS FOR DATA FROM...

  5. Protocol 20. Factor Xa Protease treatment of fusion proteins containing a Factor Xa Protease recognition sequence

    E-print Network

    Lebendiker, Mario

    of cleavage. Component Volume/reaction Final concentration 10 g fusion protein variable 0.25 g/l Factor XaProtocol 20. Factor Xa Protease treatment of fusion proteins containing a Factor Xa Protease recognition sequence Treatment of fusion proteins containing a Factor Xa Protease recognition sequence con

  6. [Chemicals as fire damaging factor].

    PubMed

    Basharin, V A; Grebeniuk, A N; Markizova, N F; Preobrazhenskaia, T N; Sarmanaev, S Kh; Tolkach, P G

    2015-01-01

    The article provides an overview of published scientific data about toxic chemical compounds formed during thermal degradation of various materials. In case of fire the complex of physical and chemical factors affect the human, along with injuries, thermal burns of the skin and respiratory tract there is a lack of oxygen in the inspired air and the impact of thermal degradation products. The greatest number of deaths in.a fire due to the inhalation by the victims smoke and toxic gases. The impact of the combination of toxic substances leads to the development of various forms of toxic process. The main causes of poisoning at the fires due to the effects of toxic substances and substances which can cause structural and functional disorders of the respiratory organ. Intoxication manifestations by some of them appear already in the fire zone, in other cases, in cases of poisoning by the compounds of the slow motion, there is the latent period of of intoxication. Knowledge of the spectrum of toxic products thermal destruction on the human during the fire, it is necessary to develop approaches to improve medical care and creation of tools of medical protection. PMID:25916033

  7. Purification & Characterization of Transcription Factors

    PubMed Central

    Nagore, LI; Nadeau, RJ; Guo, Q; Jadhav, YLA; Jarrett, HW; Haskins, WE

    2013-01-01

    Transcription factors (TFs) are essential for the expression of all proteins, including those involved in human health and disease. However, TFs are resistant to proteomic characterization because they are frequently masked by more abundant proteins due to the limited dynamic range of capillary liquid chromatography-tandem mass spectrometry and protein database searching. Purification methods, particularly strategies that exploit the high affinity of TFs for DNA response elements on gene promoters, can enrich TFs prior to proteomic analysis to improve dynamic range and penetrance of the TF proteome. For example, trapping of TF complexes specific for particular response elements has been achieved by recovering the element DNA-protein complex on solid supports. Additional methods for improving dynamic range include two- and three-dimensional gel electrophoresis incorporating electrophoretic mobility shift assays and Southwestern blotting for detection. Here we review methods for TF purification and characterization. We fully expect that future investigations will apply these and other methods to illuminate this important but challenging proteome. PMID:23832591

  8. Risk factors in cervical spondylosis

    PubMed Central

    Singh, Sudhir; Kumar, Dharmendra; Kumar, Sanjeev

    2014-01-01

    Background Cervical spondylosis is essentially a degenerative disorder common after fourth decade. It has been seen that radiological evidence of cervical spondylosis do not necessarily co-relate with clinical findings. This discrepancy has been attributed to the morphometric dimensions of the vertebrae, age, sex, race, occupation, weight and height of the patients. Objective The objective of this study is to co-relate the variables like age, sex, race, occupation, vertebral body diameter, canal diameter, canal body ratio of cervical spine vertebrae with cervical spondylosis cases with normal population. Methods In this hospital based, case control, consent based, cross-sectional, clinico-radiological study 200 individuals (controls-100, cases-100) who were subjected to lateral projection radiographs of cervical spine. Their age, sex, race, occupation, height, weight and mid-sagittal canal diameter (CD), sagittal vertebral body diameter (VBD) and the canal-body ratio (CBR) of the cervical vertebrae was recorded and analyzed statistically. Results There was no relation between vertebral dimensions and clinical groups. In radiculopathy group, age and height showed significance on univariate analysis. While only age remained significant on multivariate analysis. In neck pain group age, sex, and height showed significance on univariate analysis while in multivariate analysis age, sex and occupation were significant risk factors. PMID:25983502

  9. Environmental factors in Tourette syndrome.

    PubMed

    Hoekstra, Pieter J; Dietrich, Andrea; Edwards, Mark J; Elamin, Ishraga; Martino, Davide

    2013-07-01

    Environmental exposures during the prenatal period, perinatal stages, and postnatal life may contribute to onset and course of Tourette syndrome (TS). Pregnancy-related noxious exposures may be more frequent in pregnancies of children who will develop TS, particularly maternal smoking and prenatal life stressors. Lower birth weight and use of forceps at delivery may be associated with tic severity in the offspring; moreover, low birth weight and maternal smoking during pregnancy may affect the risk of co-morbid attention-deficit/hyperactivity and obsessive-compulsive disorders. Group A streptococcal infections as risk-modifier for TS has not been convincingly demonstrated to date, although an interaction with stressors was suggested. The PANDAS hypothesis is currently undergoing a nosological revision. Only limited anecdotal evidence supports a link of TS to other pathogens. Nevertheless, the relationship between infections and TS may be complex. Recent data point to intrinsically altered immune regulation in TS, which might predispose to both infections and autoimmune mechanisms; however, evidence of cell-mediated and antibody-mediated autoimmunity in TS is still insufficient. Psychosocial stress remains the most important contextual factor influencing tic severity, as confirmed by prospective studies. This might in part be related to enhanced reactivity of the stress response in TS patients, the mechanisms of which need to be explored further. New studies on large prospective cohorts of patients of different age and the identification of reliable biomarkers or endophenotypes indicating early, prenatal exposure to environmental insults are needed. PMID:23092654

  10. Chemotactic factor inactivators of human granulocytes.

    PubMed Central

    Brozna, J P; Senior, R M; Kreutzer, D L; Ward, P A

    1977-01-01

    During phagocytosis, neutrophils release a variety of substances that include activators and inactivators of chemotactic factors. It is generally considered that these represent hydrolytic enzymes. Elastase and cathepsin G, major proteases released from lysosomal granules during phagocytosis, contain broad hydrolytic activity. This study examined granule elastase and cathepsin G for their role as inactivators of chemotactic factors. Elastase and cathepsin G were purified from human neutrophils by Trasylol-Sepharose and CM-cellulose chromatography. Small amounts (approximately equal to 3 microgram, 1 muM) of elastase and cathepsin G, comparable to quantities released by 10(6) neutrophils during phagocytosis, completely inactivated the C5 chemotactic factor generated in human serum. Larger concentrations were needed to inactivate the C3 chemotactic factor, and when the bacterial chemotactic factor from Escherichia coli was employed, five times more elastase or cathepsin G was ineffective against this chemotactic factor. Supernatant fluid from human neutrophils that had ingested complement-coated zymosan particles contained elastase and cathepsin G and had inactivator activity for both the C5 chemotactic fragment and the bacterial factor. A specific inhibitor of elastase largely abolished the inactivator activity in the phagocytic supernates that was directed against C5 factor but did not affect the inactivator activity for the bacterial factor. Similar results occurred in studies of granule lysates. These data indicate heterogeneity in the chemotactic factor inactivator activity released by phagocytosing neutrophils. The predominant inactivator activity of the C5 chemotactic fragment is attributable to elastase and cathepsin G. PMID:334799

  11. Prediction of electron beam output factors.

    PubMed

    Mills, M D; Hogstrom, K R; Almond, P R

    1982-01-01

    A method to predict square and rectangular field output factors from the measurement of selected fields of electron beams on the Therac 20 Saturne has been developed. A two parameter fit of the square field output factor data, based on the functional dependence as predicted by a pencil beam calculational model, has proven clinically acceptable. The pencil beam distributions are given by the Fermi-Eyges theory of multiple Coulomb scattering. For a rectangular field, the output factor can be calculated from the square root of the product of the two square field output factors wtih sides equal to those of the rectangular field. If however, there is a significant asymmetry between the X and Y collimator systems, then rectangular field output factors should be predicted from the product of the X and Y one-dimensional output factors. One-dimensional output factors are defined as output factors of rectangular fields where one side remains constant and equal to the side of the square reference field. Measured data indicate either of the two methods of determining rectangular field output factors to be clinically acceptable for the Therac 20, the use of one-dimensional output factors demonstrating greater accuracy. Data show agreement to within approximately 1.5% at electron energies of 6, 9, 13, and 17 MeV. PMID:6804772

  12. Growth factor conjugation: strategies and applications.

    PubMed

    Hajimiri, Mirhamed; Shahverdi, Sheida; Kamalinia, Golnaz; Dinarvand, Rassoul

    2015-02-01

    Growth factors, first known for their essential role in the initiation of mitosis, are required for a variety of cellular processes and their localized delivery is considered as a rational approach in their therapeutic application to assure a safe and effective treatment while avoiding unwanted adverse effects. Noncovalent immobilization of growth factors as well as their covalent conjugation is amongst the most common strategies for localized delivery of growth factors. Today, immobilized and covalently conjugated growth factors are considered as a promising drug design and are widely used for protein reformulation and material design to cover the unwanted characteristics of growth factors as well as improving their functions. Selection of a suitable conjugation technique depends on the substrate chemistry and the availability of functional reactive groups in the structure of growth factor, the position of reactive groups in growth factor molecules and its relation with the receptor binding area, and the intention of creating either patterned or unpatterned conjugation. Various approaches for growth factor reformulation have been reported. This review provides an overview on chemical conjugation of growth factors and covers the relevant studies accomplished for bioconjugation of growth factors and their related application. PMID:24733811

  13. Prunus transcription factors: breeding perspectives

    PubMed Central

    Bianchi, Valmor J.; Rubio, Manuel; Trainotti, Livio; Verde, Ignazio; Bonghi, Claudio; Martnez-Gmez, Pedro

    2015-01-01

    Many plant processes depend on differential gene expression, which is generally controlled by complex proteins called transcription factors (TFs). In peach, 1533 TFs have been identified, accounting for about 5.5% of the 27,852 protein-coding genes. These TFs are the reference for the rest of the Prunus species. TF studies in Prunus have been performed on the gene expression analysis of different agronomic traits, including control of the flowering process, fruit quality, and biotic and abiotic stress resistance. These studies, using quantitative RT-PCR, have mainly been performed in peach, and to a lesser extent in other species, including almond, apricot, black cherry, Fuji cherry, Japanese apricot, plum, and sour and sweet cherry. Other tools have also been used in TF studies, including cDNA-AFLP, LC-ESI-MS, RNA, and DNA blotting or mapping. More recently, new tools assayed include microarray and high-throughput DNA sequencing (DNA-Seq) and RNA sequencing (RNA-Seq). New functional genomics opportunities include genome resequencing and the well-known synteny among Prunus genomes and transcriptomes. These new functional studies should be applied in breeding programs in the development of molecular markers. With the genome sequences available, some strategies that have been used in model systems (such as SNP genotyping assays and genotyping-by-sequencing) may be applicable in the functional analysis of Prunus TFs as well. In addition, the knowledge of the gene functions and position in the peach reference genome of the TFs represents an additional advantage. These facts could greatly facilitate the isolation of genes via QTL (quantitative trait loci) map-based cloning in the different Prunus species, following the association of these TFs with the identified QTLs using the peach reference genome.

  14. Epidermal Growth Factor Receptor Immunohistochemistry

    PubMed Central

    Hirsch, Fred R.; Dziadziuszko, Rafal; Thatcher, Nick; Mann, Helen; Watkins, Claire; Parums, Dinah V.; Speake, Georgina; Holloway, Brian; Bunn, Paul A.; Franklin, Wilbur A.

    2012-01-01

    BACKGROUND The ISEL (Iressa Survival Evaluation in Lung Cancer) clinical trial evaluated the efficacy of gefitinib versus placebo in pretreated nonsmall-cell lung cancer patients. Two different antibodies, scoring systems, and cutoff points of epidermal growth factor receptor (EGFR) protein expression were compared to predict response and survival of enrolled patients. METHODS EGFR expression was assessed in tumor samples by immunohistochemistry using the Dako EGFR pharmDx kit (scoring percent of tumor cells with positive staining) and Zymed monoclonal antibody clone 31G7 (scoring staining index derived from proportion of positive cells times staining intensity). RESULTS Data for EGFR expression were available for 379 patients for Dako and 357 patients for Zymed antibody (22% and 21%, respectively, of trial population). Objective response rates in gefitinib-treated EGFR-positive patients defined with various cutpoints with Dako antibody varied between 8% and 12%, and with Zymed antibody between 10% and 13%. Lower cutoff points with Dako antibody provided the best discrimination between EGFR-positive and EGFR-negative patients for survival hazard ratios comparing gefitinib to placebo, with a significant treatment/cutoff point interaction for 10% cutoff point (P = .049). A similar but less apparent trend was noted for Zymed antibody, although the discrimination between hazard ratios was not significant for any cutoff point analyzed. CONCLUSIONS Assessment with the Dako PharmDx kit and percentage of cells with positive staining may provide more accurate prediction of differential effect on survival with gefitinib than assessment with Zymed antibody and staining index. Using higher cutpoints to define positivity does not improve test discrimination. PMID:18219661

  15. Late Glacial to Holocene environmental variabilities: A new multi-proxy paleolimnological study of sedimentary sequences from Como (northern Italy)

    NASA Astrophysics Data System (ADS)

    Hbig, N.; Martinelli, E.; Motella, S.; Michetti, A. M.; Livio, F.; Tinner, W.; Reicherter, K.; Castelletti, L.

    2012-04-01

    Lake Como (northern Italy) is the deepest Italian lake, reaching a depth of about 425 m. The lambda-shaped lake expands about 45 km in NE-SW direction. Southwards of the hydrologically closed western branch, two sediment cores of 70 m (S1) and 65 m length (S2) were taken in the year 2005 close to the cathedral of Como (Piazza Verdi). The drilling sites are located in the middle of the Southern Alps, some 300 m from the present-day lakeshore. The cores provide the first detailed Late Glacial to Holocene multi-proxy record for the Lake Como basin. Our research is aimed at investigating the environmental and geological evolution of the Insubria Region. The multi-proxy study of the stratigraphic sequences contain geophysical, geotechnical, sedimentological, paleobotanical, and radiocarbon analyses. They have been performed for core S1 and are still in progress on core S2. With this data the working group focuses on two main issues. The first topic is the reconstruction of the natural and anthropogenic processes controlling the ground subsidence in the Como urban area (e.g., Comerci et al., 2007) and another aim is to reconstruct vegetation and land-use dynamics. In particular, 150 samples of vegetal macroremains have been collected in the palustrine deposits along S1 core, down to 31,00 m. Below this depth (dated 14C 12,496 55 yr BP - 15,050 - 14,250 cal yr BP), the amount of plant macroremains in the sediment drops dramatically. The taxonomic determination was carried out on more than 800 macroremains. They are represented by fragments of wood, leaves, needles, seeds, fruits, mosses and tiny charcoals (Motella, 2009, unpublished PhD Thesis). Picea/Larix, Pinus sp., Juniperus with Betula, found in the deeper levels (30.80 - 30.00 m), are the first arboreal taxa that colonized the shores of Lake Como, and show that the reforestation began in this area about 16,000 years ago. During the early Holocene (25.10 m) Abies alba expanded and further upwards the sequence mixed deciduous forests became important. Preliminary results of palynological analyses for a section of the core S2 (35.04 - 18.12 m), show Late Glacial sediments in the depth of 35.04 - 31.16 m, due to vegetation changes related to natural climatic variability, with an alternation of communities typical of cold (Poaceae, Artemisia, Juniperus, Pinus and Betula) and temperate climates (e.g. Quercus). Later, during the Holocene, forests composed by mostly deciduous broadleaves and Abies alba expanded. During the mid and late Holocene human impact increased and modified vegetation. This is shown by the increase of herbs and heliofilous shrubs (26.51 m), typical of deforested spaces for fields and pastures. Human exploitation of wood is represented for example by the dramatic decline of Abies alba (24.97 m). Finally, the increase of Cerealia (19.39 m) is clearly related to intensified agricultural activities. The results of further paleobotanical and geophysical analyses which are in progress will be presented during the conference. Moreover, geochemical measurements (e.g., XRF) will be performed in future for core S2. Researches realized within the project of Italy-Switzerland Cooperation SITINET "Censimento, valorizzazione e messa in rete di siti geologici e archeologici" (Census, increase of value and computerization of geological and archaeological sites). Interreg IV A "Geo-Archeositi dell'Insubria" (Geo-Archaeosites of Insubria).

  16. Roles for Growth Factors in Cancer Progression

    NSDL National Science Digital Library

    Esther Witsch (Weizmann Institute of Science)

    2010-04-01

    Under physiological conditions, cells receive fate-determining signals from their tissue surroundings, primarily in the form of polypeptide growth factors. Integration of these extracellular signals underlies tissue homeostasis. Although departure from homeostasis and tumor initiation are instigated by oncogenic mutations rather than by growth factors, the latter are the major regulators of all subsequent steps of tumor progression, namely clonal expansion, invasion across tissue barriers, angiogenesis, and colonization of distant niches. Here, we discuss the relevant growth factor families, their roles in tumor biology, as well as the respective downstream signaling pathways. Importantly, cancer-associated activating mutations that impinge on these pathways often relieve, in part, the reliance of tumors on growth factors. On the other hand, growth factors are frequently involved in evolvement of resistance to therapeutic regimens, which extends the roles for polypeptide factors to very late phases of tumor progression and offers opportunities for cancer therapy.

  17. View factors between APT target components

    SciTech Connect

    Kidman, R.B.

    1998-07-01

    In a loss-of-coolant accident (LOCA) in the accelerator production of tritium (APT) target/blanket, radiation heat transfer determines the temperature of the target components. Radiation heat-transfer analysis can only proceed if accurate component-to-component view factors are available. The authors describe and demonstrate the numerical method used to compute the view factors (also called angle factors, configuration factors, and shape factors) between complicated objects. The method is verified on simple objects that have analytic solutions, and then it is used to predict the view factors between the target components of the accelerator production of tritium target/blanket. The method is practical, easy to apply, and can accommodate difficult levels of realism.

  18. Transcriptional factors, Mafs and their biological roles

    PubMed Central

    Tsuchiya, Mariko; Misaka, Ryoichi; Nitta, Kosaku; Tsuchiya, Ken

    2015-01-01

    The Maf family of transcription factors is characterized by a typical bZip structure; these transcription factors act as important regulators of the development and differentiation of many organs and tissues, including the kidney. The Maf family consists of two subgroups that are characterized according to their structure: large Maf transcription factors and small Maf transcription factors. The large Maf subgroup consists of four proteins, designated as MAFA, MAFB, c-MAF and neural retina-specific leucine zipper. In particular, MAFA is a distinct molecule that has been attracting the attention of researchers because it acts as a strong transactivator of insulin, suggesting that Maf transcription factors are likely to be involved in systemic energy homeostasis. In this review, we focused on the regulation of glucose/energy balance by Maf transcription factors in various organs. PMID:25685288

  19. Exploratory Bi-Factor Analysis: The Oblique Case

    ERIC Educational Resources Information Center

    Jennrich, Robert I.; Bentler, Peter M.

    2012-01-01

    Bi-factor analysis is a form of confirmatory factor analysis originally introduced by Holzinger and Swineford ("Psychometrika" 47:41-54, 1937). The bi-factor model has a general factor, a number of group factors, and an explicit bi-factor structure. Jennrich and Bentler ("Psychometrika" 76:537-549, 2011) introduced an exploratory form of bi-factor

  20. Sums of divisors, perfect numbers, and factoring

    Microsoft Academic Search

    Eric Bach; Gary Miller; Jejffrey Shallit

    1984-01-01

    Let N be a positive integer, and let &sgr;(N) denote the sum of the positive integral divisors of N. We show computing &sgr;(N) is equivalent to factoring N in the following sense: there is a random polynomial time algorithm that, given &sgr;(N), produces the prime factorization of N, and &sgr;(N) can be easily computed given the factorization of N. We

  1. Erosiondiagnosis and risk factors

    Microsoft Academic Search

    A. Lussi; T. Jaeggi

    2008-01-01

    Dental erosion is a multifactorial condition: The interplay of chemical, biological and behavioural factors is crucial and\\u000a helps explain why some individuals exhibit more erosion than others. The erosive potential of erosive agents like acidic drinks\\u000a or foodstuffs depends on chemical factors, e.g. pH, titratable acidity, mineral content, clearance on tooth surface and on\\u000a its calcium-chelation properties. Biological factors such

  2. Human Monocytes Support Factor X Activation by Factor VIIa, Independent of Tissue Factor: Implications for the Therapeutic Mechanism of High-Dose Factor VIIa in Hemophilia

    Microsoft Academic Search

    Maureane Hoffman; Dougald M. Monroe; Harold R. Roberts

    1994-01-01

    bosis to complicate its use. These complications are seen when preparations of the activated vitamin-K-dependent coagulation proteins, such as Autoplex, are used to treat pa- tients with inhibitors. High-dose factor VIIa therapy has not shown a propensity to initiate DIC or thrombosis in clinical trial^.^ Factor VIIa can activate factor X in vitro in the pres- ence of phospholipid vesicles

  3. Human Factors Considerations in System Design

    NASA Technical Reports Server (NTRS)

    Mitchell, C. M. (editor); Vanbalen, P. M. (editor); Moe, K. L. (editor)

    1983-01-01

    Human factors considerations in systems design was examined. Human factors in automated command and control, in the efficiency of the human computer interface and system effectiveness are outlined. The following topics are discussed: human factors aspects of control room design; design of interactive systems; human computer dialogue, interaction tasks and techniques; guidelines on ergonomic aspects of control rooms and highly automated environments; system engineering for control by humans; conceptual models of information processing; information display and interaction in real time environments.

  4. Instantaneous power factor determined by instantaneous phasors

    SciTech Connect

    Hsu, J.S.

    1998-03-01

    The instantaneous power factor can be clearly understood from the instantaneous phasors. The unique property of instantaneous phasors is that at any instant the instantaneous three-phase currents and voltages can be represented by a set of balanced phasors. The instantaneous power factor resembles the familiar format of power factor derived from the conventional phasors. This new concept can be used for power quality monitoring, diagnostics, and compensations.

  5. Factorization of a 512Bit RSA Modulus

    Microsoft Academic Search

    Stefania Cavallar; Bruce Dodson; Arjen K. Lenstra; Walter M. Lioen; Peter L. Montgomery; Brian Murphy; Herman Te Riele; Karen Aardal; Jeff Gilchrist; Grard Guillerm; Paul C. Leyland; Jol Marchand; Franois Morain; Alec Muffett; Chris Putnam; Craig Putnam; Paul Zimmermann

    2000-01-01

    . On August 22, 1999, we completed the factorization of the512--bit 155--digit number RSA--155 by the Number Field Sieve factoringmethod (NFS). This is a new record for factoring general numbers.Moreover, 512--bit RSA keys are frequently used for the protection ofelectronic commerce---at least outside the USA---so this factorizationrepresents a breakthrough in research on RSA--based systems.The previous record, factoring the 140--digit number

  6. Synthetic heparin-binding growth factor analogs

    DOEpatents

    Pena, Louis A.; Zamora, Paul; Lin, Xinhua; Glass, John D.

    2007-01-23

    The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain that binds a heparin-binding growth factor receptor, covalently bound to a hydrophobic linker, which is in turn covalently bound to a non-signaling peptide that includes a heparin-binding domain. The synthetic heparin-binding growth factor analogs are useful as soluble biologics or as surface coatings for medical devices.

  7. Stress fractures: Pathophysiology, epidemiology, and risk factors

    Microsoft Academic Search

    Stuart J. Warden; David B. Burr; Peter D. Brukner

    2006-01-01

    A stress fracture represents the inability of the skeleton to withstand repetitive bouts of mechanical loading, which results\\u000a in structural fatigue and resultant signs and symptoms of localized pain and tenderness. To prevent stress fractures, an appreciation\\u000a of their risk factors is required. These are typically grouped into extrinsic and intrinsic risk factors. Extrinsic risk factors\\u000a for stress fractures are

  8. Pioneer transcription factors in cell reprogramming

    PubMed Central

    Iwafuchi-Doi, Makiko

    2014-01-01

    A subset of eukaryotic transcription factors possesses the remarkable ability to reprogram one type of cell into another. The transcription factors that reprogram cell fate are invariably those that are crucial for the initial cell programming in embryonic development. To elicit cell programming or reprogramming, transcription factors must be able to engage genes that are developmentally silenced and inappropriate for expression in the original cell. Developmentally silenced genes are typically embedded in closed chromatin that is covered by nucleosomes and not hypersensitive to nuclease probes such as DNase I. Biochemical and genomic studies have shown that transcription factors with the highest reprogramming activity often have the special ability to engage their target sites on nucleosomal DNA, thus behaving as pioneer factors to initiate events in closed chromatin. Other reprogramming factors appear dependent on pioneer factors for engaging nucleosomes and closed chromatin. However, certain genomic domains in which nucleosomes are occluded by higher-order chromatin structures, such as in heterochromatin, are resistant to pioneer factor binding. Understanding the means by which pioneer factors can engage closed chromatin and how heterochromatin can prevent such binding promises to advance our ability to reprogram cell fates at will and is the topic of this review. PMID:25512556

  9. Soliton form factors from lattice simulations

    SciTech Connect

    Rajantie, Arttu; Weir, David J. [Theoretical Physics Group, Blackett Laboratory, Imperial College London, London SW7 2AZ (United Kingdom)

    2010-12-01

    The form factor provides a convenient way to describe properties of topological solitons in the full quantum theory, when semiclassical concepts are not applicable. It is demonstrated that the form factor can be calculated numerically using lattice Monte Carlo simulations. The approach is very general and can be applied to essentially any type of soliton. The technique is illustrated by calculating the kink form factor near the critical point in 1+1-dimensional scalar field theory. As expected from universality arguments, the result agrees with the exactly calculable scaling form factor of the two-dimensional Ising model.

  10. Conflict-Initiating Factors in Intergenerational Relationships

    E-print Network

    Zhang, Yan Bing; Lin, Mei-Chen

    2009-12-01

    This study examined American young adults written accounts of intergenerational communication with a focus on factors that initiate conflict. Analysis of the conflict scenarios in intergenerational relationships revealed ...

  11. Factor XI and XII as antithrombotic targets

    PubMed Central

    Mller, Felicitas; Gailani, David; Renn, Thomas

    2015-01-01

    Purpose of review Arterial and venous thrombosis are major causes of morbidity and mortality, and the incidence of thromboembolic diseases increases as a population ages. Thrombi are formed by activated platelets and fibrin. The latter is a product of the plasma coagulation system. Currently available anticoagulants such as heparins, vitamin K antagonists and inhibitors of thrombin or factor Xa target enzymes of the coagulation cascade that are critical for fibrin formation. However, fibrin is also necessary for terminating blood loss at sites of vascular injury. As a result, anticoagulants currently in clinical use increase the risk of bleeding, partially offsetting the benefits of reduced thrombosis. This review focuses on new targets for anticoagulation that are associated with minimal or no therapy-associated increased bleeding. Recent findings Data from experimental models using mice and clinical studies of patients with hereditary deficiencies of coagulation factors XI or XII have shown that both of these clotting factors are important for thrombosis, while having minor or no apparent roles in processes that terminate blood loss (hemostasis). Summary Hereditary deficiency of factor XII (Hageman factor) or factor XI, plasma proteases that initiate the intrinsic pathway of coagulation, impairs thrombus formation and provides protection from vascular occlusive events, while having a minimal impact on hemostasis. As the factor XIIfactor XI pathway contributes to thrombus formation to a greater extent than to normal hemostasis, pharmacological inhibition of these coagulation factors may offer the exciting possibility of anticoagulation therapies with minimal or no bleeding risk. PMID:21730835

  12. Hematopoietic growth factors in cancer treatment.

    PubMed

    Bchner, T

    1994-05-01

    The introduction of hematopoietic growth factors during the past five years has changed the scenery of antitumor treatment. Growth factors following high-dose chemotherapy or bone marrow transplantation have become established as part of many treatment protocols. The main benefits are earlier recovery of neutrophils resulting in fewer days with fever, antibiotics and hospitalization. Growth factors were found to reduce the treatment-related morbidity and to improve the practicability of therapeutic regimens. First studies on a prospective chemotherapy dose intensification supported by growth factors are underway. As a further effect of growth factors, an attempted enhancement of antitumor cytotoxicity by recruitment of tumor cells to chemosensitivity or by modulation of antitumor drug metabolism appears realistic based on first data on growth factor priming in AML. New ways to support high-intensity and myeloablative antitumor strategies are opened by the autologous transplantation of peripheral blood progenitor cells mobilized by growth factors and also by the use of new factors like SCF and the synergistic combination of growth factors as part of future strategies against malignant disorders. PMID:8075591

  13. Matrix factorization on a hypercube multiprocessor

    SciTech Connect

    Geist, G.A.; Heath, M.T.

    1985-08-01

    This paper is concerned with parallel algorithms for matrix factorization on distributed-memory, message-passing multiprocessors, with special emphasis on the hypercube. Both Cholesky factorization of symmetric positive definite matrices and LU factorization of nonsymmetric matrices using partial pivoting are considered. The use of the resulting triangular factors to solve systems of linear equations by forward and back substitutions is also considered. Efficiencies of various parallel computational approaches are compared in terms of empirical results obtained on an Intel iPSC hypercube. 19 refs., 6 figs., 2 tabs.

  14. [Risk factors of main cancer sites].

    PubMed

    Uleckiene, Saule; Didziapetriene, Janina; Grici?te, Liudvika Laima; Urbeliene, Janina; Kasiulevicius, Vytautas; Sapoka, Virginijus

    2008-01-01

    Cancer prevention is a system of various measures devoted to avoid this disease. Primary cancer prevention means the identification, avoidance, or destruction of known risk factors. The main risk factors are smoking, diet, alcohol consumption, occupational factors, environmental pollution, electromagnetic radiation, infection, medicines, reproductive hormones, and lack of physical activity. Approximately one-third of cancers can be avoided by implementing various preventive measures. The aim of this article was to acquaint medical students, family doctors with risk factors of main cancer sites (lung, breast, colorectal, and prostate). PMID:19142058

  15. En un solemne acto que se celebr el pasado 15 de marzo, Eu-genio Tras Sagnier y Jos Saramago fueron investidos como doc-

    E-print Network

    Autonoma de Madrid, Universidad

    como "una de las figuras ms destacadas de la filosofa de nuestro tiempo. La aparicin de sus primeros Albaladejo realiz un extenso viaje por la vida y la obra del escritor, destacando su vinculacin con la

  16. La dramatizacin de una conversin al catolicismo en el auto de Caldern La protestacin de la fe (1656): el sueo como espacio de transmisin del dogma.

    E-print Network

    Paris-Sud XI, Université de

    1656-01-01

    (1656): el sueño como espacio de transmisión del dogma. Françoise GILBERT Fundamentado en un hecho espacio-temporales de la acción, mientras la cuarta sintetiza la trayectoria dramática de los como espacio de transmisión del dogma", Toulouse : France (2007)" #12;2 Religión a la cena de la

  17. [Structure and function of the factor VIII/von Willebrand factor complex].

    PubMed

    Mller, G

    1990-03-01

    In the blood plasma factor VIII is bound to the von Willebrand factor. The primary structure of the two proteins were clarified by gene clonation. Factor VIII descends from a precursor protein with 2,351 amino acids by splitting of 19 amino acid residues and is activated by partial proteolysis. In the blood coagulation factor VIII acts as co-factor for the activation of factor X by factor IX in the presence of phospholipids and Ca++ within the intrinsic coagulation system. The formation of the von Willebrand factor takes place by splitting of 22 and 741 amino acid residues, respectively, from pre-pro-von Willebrand factor via pro-von Willebrand factor. The subunits of the von Willebrand factor consist od 2,050 amino acid residues. In the blood plasma the von Willebrand factor is existing as a mixture of multimeres. Receptors of the von Willebrand factor on the thrombocytic membrane are the glycoproteins GPIb and GPIIb/GPIIIa, by means of which the adhesion of thrombocytes at the subendoethelium of the vascular wall and the aggregation of thrombocytes are mediated. PMID:2159676

  18. Local Factorization of Functions Technical Report

    E-print Network

    Tresp, Volker

    introduce a specific approximate local factorization, the local factoriz- ing approximation (LFA). In contrast to other local approximations, such as the Laplace approximation, the LFA does not rely, the LFA is accurate in case that the function factorizes in some rotated coordinate system. In the next

  19. Regulation of Growth Factor Receptors by Gangliosides

    NSDL National Science Digital Library

    Erik A. Miljan (Chicago; Children's Memorial Medical Center REV)

    2002-11-26

    Growth factor receptors are important in controlling many cellular functions, such as growth, differentiation, and disease. Growth factor receptors activate numerous signal transduction pathways within cells; however, how one growth factor receptor orchestrates multiple signal transduction pathways is not clear. This review focuses on a ubiquitous component of the plasma membrane, called "gangliosides," and how they modulate growth factor receptors at the cell membrane. Gangliosides are complex structures that consist of two parts--a lipid ceramide moiety and a carbohydrate head structure. Studies over the past two decades have demonstrated that different gangliosides can enhance or inhibit growth factor receptor activity. However, ganglioside modulation of growth factor receptors is more complex than simply stimulation or inhibition. We present and discuss three models of how gangliosides regulate growth factor receptors: (i) modulation of ligand binding, (ii) regulation of receptor dimerization, and (iii) regulation of receptor activation state and subcellular distribution. On the basis of these models, we speculate about the physiological consequences of ganglioside regulation of growth factor receptors.

  20. Nonnegative matrix factorization with quadratic programming

    Microsoft Academic Search

    Rafal Zdunek; Andrzej Cichocki

    2008-01-01

    Nonnegative Matrix Factorization (NMF) solves the following problem: flnd such nonnegative matrices A 2 RIJ + and X 2 R JK + that Y = AX, given only Y 2RIK and the assigned index J (K >> I J). Basically, the factorization is achieved by alternating minimization of a given cost function subject to nonnega- tivity constraints. In

  1. Logic extraction and factorization for low power

    Microsoft Academic Search

    Sasan Iman; Massoud Pedram

    1995-01-01

    This paper describes algebraic procedures for node extraction and factorization that target low power consump- tion. New power cost functions are introduced for the sum-of- products and factored form representations of functions. These cost functions are then used to guide the power optimi- zation procedures. It is also shown that using the proposed SOP power cost function, all extractions resulting

  2. Federal Aviation Administration Human Factors Team

    E-print Network

    Ladkin, Peter B.

    Federal Aviation Administration Human Factors Team Report on: The Interfaces Between Flightcrews-600 operated by China Airlines crashed at Nagoya, Japan, killing 264 passengers and flightcrew members category airplanes. This report is the culmination of that study. #12;Report of the FAA Human Factors Team

  3. Growth factors from genes to clinical application

    SciTech Connect

    Sara, V.R. (Dept. of Pathology, Karolinska Hospital, Stockholm (SE)); Hall, K.; Low, H. (Dept. of Endocrinology, Karolinska Hospital, Stockholm (SE))

    1990-01-01

    The last decade has witnessed an explosion in the identification of growth factors and their receptors. This has been greatly facilitated by recombinant DNA technology, which has provided the tools not only to identify these proteins at the gene level but also to produce recombinant proteins for evaluating their biological activities. With the help of such techniques, we are moving toward an understanding of the biosynthesis of growth factors and their receptors, structure-function relationships, as well as mechanisms for intracellular signal transmission. The possibility of modifying these factors has opened new fields of clinical application. In this paper, four major areas of growth factor research are presented: the characterization of growth factor genes and their protein products, growth factor receptors and signal transduction by the receptors to mediate biological action, the biological actions of the various growth factors, and the role of growth factors in health and disease and their possible clinical application. Some of the topics covered include: structure of the IGFs and their variants; isoforms of PDGF receptor types; tyrosine kinase activation; structure of G-proteins in biological membranes; possible therapeutic application of NGF in the treatment of Parkinson's and Alzheimer's diseases; PDGF's possible role in the development of several fibroproliferative diseases and its therapeutic application in wound healing; and the possible use of angiogenic inhibitors in tumor treatment.

  4. Factors that Influence Participation in Online Learning

    ERIC Educational Resources Information Center

    Vonderwell, Selma; Zachariah, Sajit

    2005-01-01

    This study explored what factors influenced learner participation in two sections of a graduate online course at a Midwestern university. Findings indicated that online learner participation and patterns of participation are influenced by the following factors: technology and interface characteristics, content area experience, student roles and

  5. RISK FACTORS FOR ASTHMA IN IRAQI CHILDREN

    Microsoft Academic Search

    ABDULGHANI MOHAMAD ALSAMARAI; MOHIB A. SALIH; AMINA HAMED ALOBAIDY; AMAR M. ALWAN; ZAINAB H. ABDULAZIZ

    Background: Although a large number of studies of asthma had been conducted, the etiology of childhood asthma is not yet established. Both life style factors and environmental exposure during early life may play important roles. Objective: To evaluate the risk factors for asthma in Iraqi primary school children. Patients and Methods: The sample consisted of 2875 children, who were between

  6. Slope Safety Factor Analysis Using ANSYS

    Microsoft Academic Search

    Zhao Shangyi; Zheng Yingren

    This paper presents an analysis method for slope safety factor through soil shear strength reduction algorithm using finite elements. When the system reaches instability, the numerical non-convergence occurs simultaneously. The safety factor is obtained by strength reduction algorithm. The numerical convergence or non-convergence is related to the yield criterion. This paper presents an analysis and comparison of several yield criterions

  7. Endogenous timing factors in bird migration

    NASA Technical Reports Server (NTRS)

    Gwinner, E. G.

    1972-01-01

    Several species of warbler birds were observed in an effort to determine what initiates and terminates migration. Environmental and endogenous timing mechanisms were analyzed. The results indicate that endogenous stimuli are dominant factors for bird migration especially for long distances. It was concluded that environmental factors act as an assist mechanism.

  8. Factors Affecting Retention in Online Courses

    ERIC Educational Resources Information Center

    Berling, Victoria L.

    2010-01-01

    The purpose of this study was to expand what is known regarding the factors that relate to successful completion of online, undergraduate college courses. It addressed 13 student factors available through archival data at Northern Kentucky University based on 1,493 students enrolled in fully online courses in fall 2008. It included programmatic

  9. The Dimensions of Common Factors in Counseling

    ERIC Educational Resources Information Center

    Leibert, Todd W.

    2011-01-01

    Common factors is a concept that offers an explanation as to what makes counseling effective. Evidence from outcome studies has implications for training and practice. The particular purpose of this paper is to review the components of a popular model of common factors, the evidence supporting them, and subsequent implications for counselor

  10. Wave packet dynamics and factorization of numbers

    E-print Network

    Holger Mack; Marc Bienert; Florian Haug; Frank S. Straub; Matthias Freyberger; Wolfgang P. Schleich

    2002-04-08

    We connect three phenomena of wave packet dynamics: Talbot images, revivals of a particle in a box and fractional revivals. The physical origin of these effects is deeply rooted in phase factors which are quadratic in the quantum number. We show that the characteristic structures in the time evolution of these systems allow us to factorize large integers.

  11. Gauss Sum Factorization with Cold Atoms

    SciTech Connect

    Gilowski, M.; Wendrich, T.; Mueller, T.; Ertmer, W.; Rasel, E. M. [Institut fuer Quantenoptik, Leibniz Universitaet Hannover, Welfengarten 1, D-30167 Hannover (Germany); Jentsch, Ch. [Astrium GmbH-Satellites, 88039 Friedrichshafen (Germany); Schleich, W. P. [Institut fuer Quantenphysik, Universitaet Ulm, Albert-Einstein-Allee 11, D-89081 Ulm (Germany)

    2008-01-25

    We report the first implementation of a Gauss sum factorization algorithm by an internal state Ramsey interferometer using cold atoms. A sequence of appropriately designed light pulses interacts with an ensemble of cold rubidium atoms. The final population in the involved atomic levels determines a Gauss sum. With this technique we factor the number N=263193.

  12. The Number of Factors in Security Returns

    Microsoft Academic Search

    Stephen J Brown

    1989-01-01

    Both factor analysis of security returns and the analysis of eigenvalues seem to indicate that a market factor explains the major part of security returns. The author finds that such evidence is consistent with an economy where there are, in fact, k \\

  13. Economic and Cultural Factors Affecting University Excellence

    ERIC Educational Resources Information Center

    Jabnoun, Naceur

    2009-01-01

    Purpose: The ranking of top universities in the world has generated increased interest in the factors that enhance university performance. The purpose of this paper is to identify economic and cultural factors that affect the number of top ranking universities in each country. Design/methodology/approach: This paper first identifies the number of

  14. The magnetic form factor of the neutron

    E-print Network

    E. E. W. Bruins

    1996-11-16

    A review of neutron form factor measurements is given. We focus on recent measurements of the neutron magnetic form factor $G_M^n$, and discuss in detail our measurements of this quantity at momentum transfers Q^2=0.1-0.6 (GeV/c)^2.

  15. Form factors in the algebraic cluster model

    NASA Astrophysics Data System (ADS)

    Bijker, Roelof

    2015-06-01

    I present a derivation of form factors in the algebraic cluster model for an arbitrary number of identical clusters. The form factors correspond to representation matrix elements which are derived in closed form for the harmonic oscillator and deformed oscillator limits. These results are relevant for applications in nuclear, molecular and hadronic physics.

  16. Vascular endothelial growth factor (VEGF) in endometriosis

    Microsoft Academic Search

    Jacques Donnez; Pierre Smoes; Stephane Gillerot; Francoise Casanas-Roux; Michelle Nisolle

    1998-01-01

    Angiogenesis is likely to be involved in the pathogenesis of endometriosis. According to the transplantation theory, when the exfoliated endometrium is attached to the periton- eal layer, the establishment of a new blood supply is essential for the survival of the endometrial implant and development of endometriosis. From the known angiogenic factors, vascular endothelial growth factor (VEGF) has emerged as

  17. Cultural Factors in Learning and Education.

    ERIC Educational Resources Information Center

    Aboud, Frances E., Ed.; Meade, Robert D., Ed.

    The Fifth Western Symposium on Learning, held November 15 and 16, 1973, considered the question of how cultural factors affect learning that produces important differences in personality. The following papers, with commentaries, are collected in this volume: (1) "Cultural Factors in Learning and Education: Opening Remarks," by Paul Woodring; (2)

  18. Electrophoretic analyses of clotting factor VIII concentrates

    Microsoft Academic Search

    Katharina Pock; Alois Jungbauer; Christoph Kannicht; Klemens Lster; Andrea Buchacher; Djuro Josic

    1998-01-01

    Preparations of clotting factor VIII (FVIII) are complex protein mixtures, regardless of whether they are made by genetically engineered cells or isolated from human plasma. Commercially available FVIII preparations contain either von Willebrand factor (vWF) or human serum albumin (HSA), both of which function as stabilizers. Apart from these, the preparations contain other plasma proteins as impurities. Such protein mixtures

  19. EM algorithms for ML factor analysis

    Microsoft Academic Search

    Donald B. Rubin; Dorothy T. Thayer

    1982-01-01

    The details of EM algorithms for maximum likelihood factor analysis are presented for both the exploratory and confirmatory models. The algorithm is essentially the same for both cases and involves only simple least squares regression operations; the largest matrix inversion required is for aq q symmetric matrix whereq is the matrix of factors. The example that is used demonstrates that

  20. The factor 2 in fundamental physics

    Microsoft Academic Search

    Peter Rowlands

    2001-01-01

    A brief history is given of the factor 2, starting in the most elementary considerations of geometry and kinematics of uniform acceleration, and moving to relativity, quantum mechanics and particle physics. The basic argument is that in all the significant cases in which the factor 2 or 1\\/2 occurs in fundamental physics, whether classical, quantum or relativistic, the same physical

  1. Risk factors and cardiovascular disease in Turkey

    Microsoft Academic Search

    Altan Onat

    2001-01-01

    Cardiovascular risk factors as well as morbidity and mortality from coronary heart disease among Turkish adults are herein reviewed. Lipids and lipoproteins are in focus, but other relevant risk factors are also discussed. Turks have distinctively low levels of total and high-density lipoprotein (HDL)-cholesterol, associated with high levels of hepatic lipase and fasting triglycerides. In addition, physical inactivity is common

  2. Factors that influence Internet users' privacy perception

    Microsoft Academic Search

    Renata Mekovec; Neven Vrcek

    2011-01-01

    Privacy concerns are identified as one of the main factors that have a negative impact on Internet users' online behaviour. Often, Internet users do not have confidence that a web site will ensure their privacy either in collection nor in future usage of their personal information. In this article we propose a categorization of factors that can influence users' privacy

  3. Biased estimation of Rician K factor

    Microsoft Academic Search

    Nitesh Shroff; K. Giridhar

    2007-01-01

    The time varying envelope of the received signal, for the case when a line of sight (LoS) component exists between the transmitter and the receiver, is described by a Rician distribution with Rician factor K. The Rician factor is a measure of the severity of the fading, with K = 0 being the most severe Rayleigh fading, and K =

  4. Release of growth factors after arthroscopic acromioplasty.

    PubMed

    Randelli, Pietro; Margheritini, Fabrizio; Cabitza, Paolo; Dogliotti, Giada; Corsi, Massimiliano M

    2009-01-01

    It has recently been postulated that a variety of growth factors may be released from cancellous bone after an acromioplasty. The aim of this study was to demonstrate the presence of growth factors in the subacromial space after acromioplasty. Between October 2006 and March 2007, 23 patients underwent arthroscopic acromioplasty. A sample of at least 3 ml of fluid from the shoulder was obtained 15 min after the end of the procedure. At the same time another sample of 3 ml of the patient's venous blood was obtained as a control. The concentrations of growth factors in the fluids collected were determined using enzyme-linked immunosorbent assay (ELISA). The growth factors assayed were platelet-derived growth factor-AB (PDGF-AB), basic fibroblast growth factor basic (bFGF) and transforming growth factor beta 1 (TGF-beta1). The concentrations of TGF-beta1 (p = 0.0001), PDGF-AB (p = 0.02), and bFGF (p < 0.0001) were significantly higher in the fluid from the subacromial space than in the blood sample. There are high concentrations of several growth factors in the subacromial space after acromioplasty. PMID:18974971

  5. Risk factors identified for certain lymphoma subtypes

    Cancer.gov

    In a large international collaborative analysis of risk factors for non-Hodgkin lymphoma (NHL), scientists were able to quantify risk associated with medical history, lifestyle factors, family history of blood or lymph-borne cancers, and occupation for 11 different NHL subtypes, including less common subtypes.

  6. Convolutional Factor Graphs as Probabilistic Models

    Microsoft Academic Search

    Yongyi Mao; Frank R. Kschischang; Brendan J. Frey

    2004-01-01

    Based on a recent development in the area of error control coding, we introduce the no- tion of convolutional factor graphs (CFGs) as a new class of probabilistic graphical mod- els. In this context, the conventional fac- tor graphs are referred to as multiplicative factor graphs (MFGs). This paper shows that CFGs are natural models for probability functions when summation

  7. GATA transcription factors and cardiac development

    Microsoft Academic Search

    Frdric Charron; Mona Nemer

    1999-01-01

    Three members of the GATA family of transcription factors, GATA-4, -5, and -6, are expressed in the developing heart. One family member, GATA-5, is restricted to the endocardium while the other two, GATA-4 and -6, are present in the myocardium where they apparently fulfil distinct functions. The mechanisms underlying GATA factor specificity are not fully understood but may involve interaction

  8. Developmental Risk Factors for Sexual Offending.

    ERIC Educational Resources Information Center

    Lee, Joseph K. P.; Jackson, Henry J.; Pattison, Pip; Ward, Tony

    2002-01-01

    A study involving 64 Australian sex offenders and 33 non-sex offenders found childhood emotional abuse and family dysfunction, childhood behavior problems, and childhood sexual abuse were developmental risk factors for paraphilia. Emotional abuse and family dysfunction was found to be a risk factor for pedophilia, exhibitionism, rape, or multiple

  9. Shift factors in ERCOT congestion pricing

    E-print Network

    Baldick, Ross

    Shift factors in ERCOT congestion pricing Ross Baldick* March 5, 2003 1. Introduction In this paper summarize the ERCOT commercial transmission model, introducing and explaining "shift factors" and their role-run, such poor economic decisions can also encourage bad choices for the location of new generation, load

  10. Factors Contributing to Institutions Achieving Environmental Sustainability

    ERIC Educational Resources Information Center

    James, Matthew; Card, Karen

    2012-01-01

    Purpose: The purpose of this paper is to determine what factors contributed to three universities achieving environmental sustainability. Design/methodology/approach: A case study methodology was used to determine how each factor contributed to the institutions' sustainability. Site visits, fieldwork, document reviews, and interviews with

  11. A Computational Approach to Factoring Large Integers

    E-print Network

    Nelson Petulante

    2009-10-29

    To factor an integer N, given that it is equal to the product of two primes, it suffices to find an integer d satisfying a certain simple numerical test. In this approach, the factorization problem equates to the problem of designing an optimal data base of values d to be tested.

  12. Meson form factors and nonperturbative gluon propagators

    Microsoft Academic Search

    M. B. Gay Ducati; W. K. Sauter

    2003-01-01

    The meson (pion and kaon) form factor is calculated in the perturbative framework with alternative forms for the running coupling constant and the gluon propagator in the infrared kinematic region. These modified forms are employed to test the sensibility of the meson form factor to the nonperturbative contributions. It is a powerful discriminating quantity and the results obtained with a

  13. Family Factors Predicting Categories of Suicide Risk

    ERIC Educational Resources Information Center

    Randell, Brooke P.; Wang, Wen-Ling; Herting, Jerald R.; Eggert, Leona L.

    2006-01-01

    We compared family risk and protective factors among potential high school dropouts with and without suicide-risk behaviors (SRB) and examined the extent to which these factors predict categories of SRB. Subjects were randomly selected from among potential dropouts in 14 high schools. Based upon suicide-risk status, 1,083 potential high school

  14. Preharvest factors affecting physiological disorders of fruit

    Microsoft Academic Search

    Ian Ferguson; Richard Volz; Allan Woolf

    1999-01-01

    Development of disorders during postharvest ripening and storage of fruit depends on a range of preharvest factors. The most obvious of these is maturity of fruit at harvest. However, a number of other factors may be just as important in ripening-related disorders and in determining how fruit respond to low temperatures or other imposed postharvest conditions. Fruiting position on the

  15. Bayesian Clustering of Transcription Factor Binding Motifs

    E-print Network

    Jensen, Shane T.

    Bayesian Clustering of Transcription Factor Binding Motifs Shane T. JENSEN and Jun S. LIU Genes are often regulated in living cells by proteins called transcription factors that bind directly to short appearance, which is called a motif. Several recent studies of transcriptional regulation require

  16. Coagulation Factors in Controlling Traumatic Bleeds

    E-print Network

    Pillow, Jonathan

    Coagulation Factors in Controlling Traumatic Bleeds: FFP, PCC, or Lucky Sevens? Rose Sohraby, Pharm IV. Mechanisms of blood coagulation1,5 a. Blood coagulation cascade (SEE APPENDIX B) #12;R. Sohraby 3 coagulation activates FIX and FX i. Tissue factor pathway inhibitor (TFPI): inhibits catalytic action of TF

  17. Factors Associated with Eating Disorders in Women

    Microsoft Academic Search

    Christina Knowles; Faculty Mentor; Frances Smith

    Although various factors associated with eating disorders have been studied, no comprehensive source of research findings was identified in this review. The purpose of this study was to identify and synthesize research findings of factors associated with eating disorders in women published from 1992-2008. These findings may be useful to nurses, other professionals, families, and the public to facilitate the

  18. Factor Structure of the Burden Interview

    Microsoft Academic Search

    Bob G. Knight; Lauren S. Fox; Chih-Ping Chou

    2000-01-01

    Zarit's Burden Interview is the most commonly used measure of burden among family caregivers for demented older adults, but has been criticized for its diverse item content and lack of correspondence to theoretically based multidimensional burden scales. The factor structure of this measure of burden was examined in a sample of 220 family caregivers of demented elderly. The implied 1-factor

  19. Career Indecision: Three Factors from Decision Theory.

    ERIC Educational Resources Information Center

    Germeijs, Veerle; De Boeck, Paul

    2003-01-01

    Factor analyses of 174 high school students' data differentiated three sources of career indecision: information about alternatives, valuation of alternatives, and uncertainty about outcomes. Only valuation and outcome factors were empirically associated with career indecision and both mediated between general indecisiveness and career indecision.

  20. Seismic Quality Factors Estimation From Spectral Correlation

    Microsoft Academic Search

    Senlin Yang; Jinghuai Gao

    2008-01-01

    This letter describes a method for estimating seismic quality (Q) factors from spectral correlation (SC). For a linear frequency attenuation model, the SC coefficient is examined between the amplitude spectrum of a reference pulse multiplied by an absorption filter and that of a target pulse, and then, the Q factor can be determined from the absorption filter which yields the