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Sample records for electron donating protective

  1. Hybrid [5]Radialenes with Bispyrroloheteroles: New Electron-Donating Units.

    PubMed

    Higashino, Tomohiro; Imahori, Hiroshi

    2015-09-14

    Bispyrroloheteroles have been synthesized to address their intrinsic structural, optical, and electrochemical properties. The X-ray crystal structures and calculated natural bond orbital (NBO) bond orders unambiguously demonstrated the existence of a two pyrrole-fused five-membered ring with short exocyclic C-C double bonds and long endocyclic C-C single bonds, supporting that the bispyrroloheteroles are rare examples of structurally characterized hybrid [5]radialenes. The bispyrroloheteroles were found to act as an electron-donating unit, which would be fascinating for the rational design of new charge-transporting and donor-acceptor photovoltaic materials as well as versatile charge-transfer complexes. PMID:26242481

  2. Protection behaviour: a phenomenon affecting organ and tissue donation in the 21st century?

    PubMed

    Kent, B C

    2004-03-01

    UK statistics show that whilst waiting lists for transplantation surgery continue to increase, donor numbers are static. This paper describes the hermeneutic phase of a mixed method study and puts forward the concept of protection behaviour as one explanation for nurses' reticence to discuss post-mortem donation wishes with patients' relatives. The desire to protect appears to influence attitudes, confidence levels and perceived ability to become involved in donor identification and donation discussion, consequently affecting the availability of transplantable organs and tissue. By understanding more fully why protective behaviours are employed, it increases the likelihood of a solution being found. PMID:14967184

  3. Simultaneous electrochemical and electron paramagnetic resonance studies of carotenoids. Effect of electron donating and accepting substituents

    SciTech Connect

    Jeevarajan, A.S.; Khaled, M.; Kispert, L.D. )

    1994-08-11

    A series of substituted phenyl-7[prime]-apocarotenoids with varying electron donating and accepting substituents was examined by cyclic voltammogram (CV) and simultaneous electrochemical electron paramagnetic resonance (SEEPR). Carotenoids substituted with electron donating groups are more easily oxidized than those with electron accepting substituents. Comproportionation constants for the dication and the neutral species were measured by SEEPR techniques and by simulation of the CVs. The [Delta]H[sub pp] of the SEEPR spectrum of the cation radicals varies from 13.2 to 15.6 G, and the g factors are 2.0027 [+-] 0.0002. These EPR parameters suggest a polyene [pi]-cation radical structure. The CVs are calculated using DigiSim, a CV simulation program, and the proposed mechanism involves three electrode reactions and two homogeneous reactions. 24 refs., 3 figs., 2 tabs.

  4. Effect of electron donating groups on polyphenol-based antioxidant dendrimers.

    PubMed

    Lee, Choon Young; Nanah, Cyprien N; Held, Rich A; Clark, Amanda R; Huynh, Uyen G T; Maraskine, Marina C; Uzarski, Rebecca L; McCracken, John; Sharma, Ajit

    2015-04-01

    Numerous studies have reported the beneficial effects of antioxidants in human diseases. Among their biological effects, a majority of antioxidants scavenge reactive radicals in the body, thereby reducing oxidative stress that is associated with the pathogenesis of many diseases. Antioxidant dendrimers are a new class of potent antioxidant compounds reported recently. In this study, six polyphenol-based antioxidant dendrimers with or without electron donating groups (methoxy group) were synthesized in order to elucidate the influence of electron donating groups (EDG) on their antioxidant activities. Syringaldehyde (2 ortho methoxy groups), vanillin (1 ortho methoxy group), and 4-hydroxybenzaldehyde (0 methoxy group) were derivatized with propargylamine to form building blocks for the dendrimers. All the six dendrimers contain polyether cores, which were synthesized by attaching pentaerythritol and methyl α-d-glucopyranoside to in-house prepared spacer units. To prepare generation 1 antioxidant dendrimers, microwave energy and granulated metallic copper catalyst were used to link the cores and building blocks together via alkyne-azide 1,3-cycloaddition click chemistry. These reaction conditions resulted in high yields of the target dendrimers that were free from copper contamination. Based on DPPH antioxidant assay, antioxidant dendrimers decorated with syringaldehyde and vanillin exhibited over 70- and 170-fold increase in antioxidant activity compared to syringaldehyde and vanillin, respectively. The antioxidant activity of dendrimers increased with increasing number of EDG groups. Similar results were obtained when the dendrimers were used to protect DNA and human LDL against organic carbon and nitrogen-based free radicals. In addition, the antioxidant dendrimers did not show any pro-oxidant activity on DNA in the presence of physiological amounts of copper. Although the dendrimers showed potent antioxidant activities against carbon and nitrogen free radicals

  5. Effect of Electron Donating Groups on Polyphenol-based Antioxidant Dendrimers

    PubMed Central

    Lee, Choon Young; Nanah, Cyprien; Held, Rich; Clark, Amanda; Huynh, Uyen; Maraskine, Marina C.; Uzarski, Rebecca L.; McCracken, John; Sharma, Ajit

    2015-01-01

    Numerous studies have reported the beneficial effects of antioxidants in human diseases. Among their biological effects, a majority of antioxidants scavenge reactive radicals in the body, thereby reducing oxidative stress that is associated with the pathogenesis of many diseases. Antioxidant dendrimers are a new class of potent antioxidant compounds reported recently. In this study, six polyphenol-based antioxidant dendrimers with or without electron donating groups (methoxy group) were synthesized in order to elucidate the influence of electron donating groups (EDG) on their antioxidant activities. Syringaldehyde (2 ortho methoxy groups), vanillin (1 ortho methoxy group), and 4-hydroxybenzaldehyde (0 methoxy group) were derivatized with propargylamine to form building blocks for the dendrimers. All the six dendrimers contain polyether cores, which were synthesized by attaching pentaerythritol and methyl α-D-glucopyranoside to in-house prepared spacer units. To prepare generation 1 antioxidant dendrimers, microwave energy and granulated metallic copper catalyst were used to link the cores and building blocks together via alkyne-azide 1,3-cycloaddition click chemistry. These reaction conditions resulted in high yields of the target dendrimers that were free from copper contamination. Based on DPPH antioxidant assay, antioxidant dendrimers decorated with syringaldehyde and vanillin exhibited over 70- and 170-fold increase in antioxidant activity compared to syringaldehyde and vanillin, respectively. The antioxidant activity of dendrimers increased with increasing number of EDG groups. Similar results were obtained when the dendrimers were used to protect DNA and human LDL against organic carbon and nitrogen-based free radicals. In addition, the antioxidant dendrimers did not show any pro-oxidant activity on DNA in the presence of physiological amounts of copper. Although the dendrimers showed potent antioxidant activities against carbon and nitrogen free radicals

  6. A BPTTF-based self-assembled electron-donating triangle capable of C60 binding.

    PubMed

    Goeb, Sébastien; Bivaud, Sébastien; Dron, Paul Ionut; Balandier, Jean-Yves; Chas, Marcos; Sallé, Marc

    2012-03-25

    A kinetically stable self-assembled redox-active triangle is isolated. The resulting electron-donating cavity, which incorporates three BPTTF units, exhibits a remarkable binding ability for electron-deficient C(60), supported by a favorable combination of structural and electronic features. PMID:22344044

  7. Electronic Tool for Distribution and Allocation of Heart on Donation and Transplantation in Mexico.

    PubMed

    Maqueda Tenorio, S E; Meixueiro Daza, L A; Maqueda Estrada, S

    2016-03-01

    In Mexico and globally, organs and/or tissues donated from deceased people are insufficient to cover the demand for transplants. In 2014, a rate of 3.6 organ donors per million in habitants was recorded; this is reflected in the transplants performed, including heart transplantation, with a rate of 0.4 per million population. According to the legal framework of Mexico, the National Transplant Center is responsible for coordinating National Subsystem of donation and transplantation, and one of its functions is to integrate and backup information regarding donation and transplantation through the National Transplant Registry System. In July 2015, 45 people were registered in the database of patients waiting for a heart transplant, of which 34.61% were female recipients and 65.39% male. Distribution and allocation processes are a key element to provide a fair distribution for those patients waiting for that organ; thus the creation of an electronic tool is proposed, one that aims to support the decision of the donation and/or transplants coordination committee by providing the necessary elements to make this process more efficient. PMID:27110003

  8. Cycloadditions of 1,2,3-Triazines Bearing C5-Electron Donating Substituents: Robust Pyrimidine Synthesis.

    PubMed

    Glinkerman, Christopher M; Boger, Dale L

    2015-08-21

    The examination of the cycloaddition reactions of 1,2,3-triazines 17-19, bearing electron-donating substituents at C5, are described. Despite the noncomplementary 1,2,3-triazine C5 substituents, amidines were found to undergo a powerful cycloaddition to provide 2,5-disubstituted pyrimidines in excellent yields (42-99%; EDG = SMe > OMe > NHAc). Even select ynamines and enamines were capable of cycloadditions with 17, but not 18 or 19, to provide trisubstituted pyridines in modest yields (37-40% and 33% respectively). PMID:26172042

  9. On the possibility to accelerate the thermal isomerizations of overcrowded alkene-based rotary molecular motors with electron-donating or electron-withdrawing substituents.

    PubMed

    Oruganti, Baswanth; Durbeej, Bo

    2016-09-01

    We employ computational methods to investigate the possibility of using electron-donating or electron-withdrawing substituents to reduce the free-energy barriers of the thermal isomerizations that limit the rotational frequencies achievable by synthetic overcrowded alkene-based molecular motors. Choosing as reference systems one of the fastest motors known to date and two variants thereof, we consider six new motors obtained by introducing electron-donating methoxy and dimethylamino or electron-withdrawing nitro and cyano substituents in conjugation with the central olefinic bond connecting the two (stator and rotator) motor halves. Performing density functional theory calculations, we then show that electron-donating (but not electron-withdrawing) groups at the stator are able to reduce the already small barriers of the reference motors by up to 18 kJ mol(-1). This result outlines a possible strategy for improving the rotational frequencies of motors of this kind. Furthermore, exploring the origin of the catalytic effect, it is found that electron-donating groups exert a favorable steric influence on the thermal isomerizations, which is not manifested by electron-withdrawing groups. This finding suggests a new mechanism for controlling the critical steric interactions of these motors. Graphical Abstract The introduction of electron-donating groups in one of the fastest rotary molecular motors known to date is found to reduce the free-energy barriers of the thermal steps that limit the rotational frequencies by up to 18 kJ mol(-1). PMID:27553304

  10. Selective visualization of point defects in carbon nanotubes at the atomic scale by an electron-donating molecular tip.

    PubMed

    Nishino, Tomoaki; Kanata, Satoshi; Umezawa, Yoshio

    2011-07-14

    Electron-donating molecular tips were used for the observation of single-walled carbon nanotubes (SWNTs). Defects in SWNTs were selectively visualized at the atomic scale on the basis of charge-transfer interaction with the molecular tip. PMID:21629907

  11. Donating Blood

    MedlinePlus

    ... can give blood every 56 days. Before Donating Blood donation starts before you walk in the door of ... regenerate the red blood cells lost during a blood donation. An iron-fortified diet plus daily iron tablets ...

  12. Donation FAQs

    MedlinePlus

    ... Ways to give How your gift saves lives Donate cord blood Cord blood is changing lives Federal cord blood ... Cord blood options Sibling directed donation How to donate cord blood Participating hospitals Cord blood FAQs Learn if you ...

  13. Who should donate blood? Policy decisions on donor deferral criteria should protect recipients and be fair to donors.

    PubMed

    Brailsford, S R; Kelly, D; Kohli, H; Slowther, A; Watkins, N A

    2015-08-01

    An important element in the development of voluntary blood donation schemes throughout the world has been the attention given to minimising the risk to recipients of donated blood, primarily the risk of transfusion transmitted infections. In response to the appearance of human immunodeficiency virus (HIV) in the 1980s a range of national policies emerged that excluded populations at high risk of contracting HIV from donating blood, with a particular focus on men who have sex with men (MSM), the primary reason being the protection of recipients of donated blood. Recently some countries, including the UK, have revised their policies, informed by advances in screening tests, epidemiological evidence of transmission rates and an increasing concern about unfair discrimination of specific groups in society. Policy makers face a difficult task of balancing safety of recipients; an adequate blood supply for those who require transfusion; and societal/legal obligations to treat everyone fairly. Given that no transfusion is risk free, the question is what degree of risk is acceptable in order to meet the needs of recipients and society. Decisions about acceptance of risk are complex and policy makers who set acceptable risk levels must provide ethically justifiable reasons for their decisions. We suggest it is possible to provide a set of reasons that stakeholders could agree are relevant based on careful evaluation of the evidence of all relevant risks and explicit acknowledgement of other morally relevant values. We describe using such a process in the Safety of Blood Tissue and Organs (SaBTO) review of donor deferral criteria related to sexual behaviour. PMID:26190553

  14. Electron donation to the flavoprotein NifL, a redox-sensing transcriptional regulator.

    PubMed

    Macheroux, P; Hill, S; Austin, S; Eydmann, T; Jones, T; Kim, S O; Poole, R; Dixon, R

    1998-06-01

    Transcriptional control of the nitrogen fixation (nif) genes in response to oxygen in Azotobacter vinelandii is mediated by nitrogen fixation regulatory protein L (NifL), a regulatory flavoprotein that modulates the activity of the transcriptional activator nitrogen fixation regulatory protein A (NifA). CD spectra of purified NifL indicate that FAD is bound to NifL in an asymmetric environment and the protein is predominantly alpha-helical. The redox potential of NifL is -226 mV at pH 8 as determined by the enzymic reduction of NifL by xanthine oxidase/xanthine in the presence of appropriate mediators. The reduction of NifL by xanthine oxidase prevented NifL from acting as an inhibitor of NifA. In the absence of electron mediators NifL could also be reduced by Escherichia coli flavohaemoprotein (Hmp) with NADH as reductant. Hmp contains a globin-like domain with haem B as prosthetic group and an FAD-containing oxidoreductase module. The carboxyferrohaem form of Hmp was competent to reduce NifL, suggesting that electron donation to NifL originates from the flavin in Hmp rather than by direct electron transfer from the haem. Spinach ferredoxin:NAD(P) oxidoreductase, which adopts a folding similar to the FAD- and NAD-binding domains of Hmp, also reduced NifL with NADH as reductant. Re-oxidation of NifL occurs rapidly in the presence of air, raising the possibility that NifL might sense intracellular oxygen. We propose a physiological redox cycle in which the oxidation of NifL by oxygen and hence the activation of its inhibitory properties occurs rapidly, in contrast with the switch from the active to the reduced form of NifL, which occurs more slowly. PMID:9601070

  15. N2 activation by an iron complex with a strong electron-donating iminophosphorane ligand.

    PubMed

    Suzuki, Tatsuya; Wasada-Tsutsui, Yuko; Ogawa, Takahiko; Inomata, Tomohiko; Ozawa, Tomohiro; Sakai, Yoichi; Fryzuk, Michael D; Masuda, Hideki

    2015-10-01

    A new tridentate cyclopentane-bridged iminophosphorane ligand, N-(2-diisopropylphosphinophenyl)-P,P-diisopropyl-P-(2-(2,6-diisopropylphenylamido)cyclopent-1-enyl)phosphoranimine (NpNPiPr), was synthesized and used in the preparation of a diiron dinitrogen complex. The reaction of the iron complex FeBr(NpNPiPr) with KC8 under dinitrogen yielded the dinuclear dinitrogen Fe complex [Fe(NpNPiPr)]2(μ-N2), which was characterized by X-ray analysis and resonance Raman and NMR spectroscopies. The X-ray analysis revealed a diiron complex bridged by the dinitrogen molecule, with each metal center coordinated by an NpNPiPr ligand and dinitrogen in a trigonal-monopyramidal geometry. The N–N bond length is 1.184(6) Å, and resonance Raman spectra indicate that the N–N stretching mode ν(14N2/15N2) is 1755/1700 cm–1. The magnetic moment of [Fe(NpNPiPr)]2(μ-N2) in benzene-d6 solution, as measured by 1H NMR spectroscopy by the Evans method, is 6.91μB (S = 3). The Mössbauer spectrum at 78 K showed δ = 0.73 mm/s and ΔEQ = 1.83 mm/s. These findings suggest that the iron ions are divalent with a high-spin configuration and that the N2 molecule has (N═N)2– character. Density functional theory calculations performed on [Fe(NpNPiPr)]2(μ-N2) also suggested that the iron is in a high-spin divalent state and that the coordinated dinitrogen molecule is effectively activated by π back-donation from the two iron ions (dπ) to the dinitrogen molecule (πx* and πy*). This is supported by cooperation between a large negative charge on the iminophosphorane ligand and strong electron donation and effective orbital overlap between the iron dπ orbitals and N2 π* orbitals supplied by the phosphine ligand. PMID:26135343

  16. Blood Donation Process

    MedlinePlus

    ... Home > Donating Blood > Donation Process Printable Version Donation Process View Video Getting Ready for Your Donation The ... worry about. Make a Donation Appointment The Donation Process Step by Step Donating blood is a simple ...

  17. Nanostructures and electronic properties of a high-efficiency electron-donating polymer.

    PubMed

    Bhatta, Ram S; Perry, David S; Tsige, Mesfin

    2013-11-27

    The development of organic photovoltaic (OPV) solar cells has seeded a bright hope of achieving low-cost solar energy harvesting. Practical realization and successful commercialization require enhancing the efficiency of solar energy harvesting, which, in turn, relies on the core understanding of structure-property relationships in OPV materials. Here, we report the first large-scale density functional calculations of the nanoconformational and electronic properties of the thieno[3,4-b]thiophene-alt-benzodithiophene copolymer (PTB7), a high-efficiency OPV material. These first-principles results include the chain length dependence of the torsional potential, the nearest-neighbor torsional coupling, the band gap, and the electronic conjugation length. Importantly, PTB7 was found to have a torsional potential almost independent of chain length, very weak nearest-neighbor torsional coupling, a low band gap (∼1.8 eV), and a very long conjugation length (∼147 Å) compared to the other conjugated polymers like polythiophene and poly(3-alkylthiophene). These results suggest that PTB7 can be an efficient electron donor for OPV devices. PMID:24219789

  18. Flavodoxin 1 of Azotobacter vinelandii: characterization and role in electron donation to purified assimilatory nitrate reductase.

    PubMed

    Gangeswaran, R; Eady, R R

    1996-07-01

    Flavodoxins synthesized by Azotobacter vinelandii strain UW 36 during growth on nitrate as nitrogen source were separated by FPLC on a Mono Q column into two species, flavodoxin 1 (AvFld 1) and flavodoxin 2 (AvFld 2). Both proteins migrated as single bands on SDS/PAGE. AvFld 1 was approx. 5-fold more abundant than AvFld 2 in the unresolved flavodoxin mixture. N-terminal amino acid analysis showed the sequence of AvFld 2 to correspond to the nif F gene product, an electron donor to nitrogenase. The sequences also show that these species corresponded to the flavodoxins Fld A and Fld B isolated from N2-grown cultures of the closely related organism Azotobacter throococcum [Bagby, Barker, Hill, Eady and Thorneley (1991) Biochem.J.277, 313-319]. Electrospray mass spectrometry gave M, values for the polypeptides of 19430 +/- 3 and 19533 +/- 5 respectively. 31P-NMR measurements showed that in addition to the phosphate associated with the FMN (delta = -136.3 p.p.m. and -135.48 p.p.m.), AvFld 1 had a signal at delta = -142.1 p.p.m. and AvFld 2 at delta = -138.59 p.p.m. present in substoichiometric amounts with FMN. These appeared to arise from unstable species since they were readily lost on further manipulation of the proteins. The mid-point potentials of the semiquinone hydroquinone redox couples were -330 mV and -493 mV for AvFld 1 and AvFld 2 respectively, but only AvFld 1 was competent in donating electrons to the purified assimilatory nitrate reductase of A. vinelandii to catalyse the reduction of nitrate to nitrite. Flavodoxin isolated from NH4(+)-grown cells (Fld 3) also functioned as electron donor at half the rate of AvFld 1, but ferredoxin 1 from A. chroococcum did not. PMID:8694750

  19. Organ Donation

    MedlinePlus

    Organ donation takes healthy organs and tissues from one person for transplantation into another. Experts say that the organs ... and bone marrow Cornea Most organ and tissue donations occur after the donor has died. But some ...

  20. Driving force dependence of charge separation and recombination processes in dyads of nucleotides and strongly electron-donating oligothiophenes.

    PubMed

    Lin, Shih-Hsun; Fujitsuka, Mamoru; Ishikawa, Mayuka; Majima, Tetsuro

    2014-10-23

    Charge transfer in DNA has attracted great attention of scientists because of its importance in biological processes. However, our knowledge on excess-electron transfer in DNA still remains limited in comparison to numerous studies of hole transfer in DNA. To clarify the dynamics of excess-electron transfer in DNA by photochemical techniques, new electron-donating photosensitizers should be developed. Herein, a terthiophene and two 3,4-ethylenedioxythiophene oligomers were used as photosensitizers in dyads including natural nucleobases as electron acceptors. The charge separation and recombination processes in the dyads were investigated by femtosecond laser flash photolysis, and the driving force dependence of these rate constants was discussed on the basis of the Marcus theory. From this study, the conformation effect on charge recombination process was found. We expect that 3,4-ethylenedioxythiophene oligomers are useful in investigation of excess-electron-transfer dynamics in DNA. PMID:25265410

  1. Remote Electronic Effects by Ether Protecting Groups Fine-Tune Glycosyl Donor Reactivity.

    PubMed

    Heuckendorff, Mads; Poulsen, Lulu Teressa; Jensen, Henrik H

    2016-06-17

    It was established that para-substituted benzyl ether protecting groups affect the reactivity of glycosyl donors of the thioglycoside type with the N-iodosuccinimide/triflic acid promoter system. Having electron donating p-methoxybenzyl ether (PMB) groups increased the reactivity of the donor in comparison to having electron withdrawing p-chloro (PClB) or p-cyanobenzyl ether (PCNB) protecting groups, which decreased the reactivity of the glycosyl donor relative to the parent benzyl ether (Bn) protected glycosyl donor. These findings were used to perform the first armed-disarmed coupling between two benzylated glucosyl donors by tuning their reactivity. In addition, the present work describes a highly efficient palladium catalyzed multiple cyanation and methoxylation of p-chlorobenzyl protected thioglycosides. The results of this paper regarding both the different electron withdrawing properties of various benzyl ethers and the efficient and multiple protecting group transformations are applicable in general organic chemistry and not restricted to carbohydrate chemistry. PMID:27224456

  2. Charge-transfer complex formation in gelation: the role of solvent molecules with different electron-donating capacities.

    PubMed

    Basak, Shibaji; Bhattacharya, Sumantra; Datta, Ayan; Banerjee, Arindam

    2014-05-01

    A naphthalenediimide (NDI)-based synthetic peptide molecule forms gels in a particular solvent mixture (chloroform/aromatic hydrocarbon, 4:1) through charge-transfer (CT) complex formation; this is evident from the corresponding absorbance and fluorescence spectra at room temperature. Various aromatic hydrocarbon based solvents, including benzene, toluene, xylene (ortho, meta and para) and mesitylene, have been used for the formation of the CT complex. The role of different solvent molecules with varying electron-donation capacities in the formation of CT complexes has been established through spectroscopic and computational studies. PMID:24677404

  3. Electron-Donating Para-Methoxy Converts a Benzamide-Isoquinoline Derivative into a Highly Sigma-2 Receptor Selective Ligand

    PubMed Central

    Hajipour, Abdol R.; Guo, Lian-Wang; Pal, Arindam; Mavlyutov, Timur; Ruoho, Arnold E.

    2011-01-01

    The sigma-2 (σ2) receptor has been suggested to be a promising target for pharmacological interventions to curb tumor progression. Development of σ2-specific ligands, however, has been hindered by lack of understanding of molecular determinants that underlie selective ligand-σ2 interactions. Here we have explored effects of electron donating and withdrawing groups on ligand selectivity for the σ2 versus σ1 receptor using new benzamide-isoquinoline derivatives. The electron-donating methoxy group increased but the electron-withdrawing nitro group decreased σ2 affinity. In particular, an extra methoxy added to the para-position (5e) of the benzamide phenyl ring of 5f dramatically improved (631 fold) the σ2 selectivity relative to the σ1 receptor. This para-position provided a sensitive site for effective manipulation of the sigma receptor subtype selectivity using either the methoxy or nitro substituent. Our study provides a useful guide for further improving the σ2-over-σ1 selectivity of new ligands. PMID:22055714

  4. Effects of surface chemistry of activated carbon on the adsorption of aromatics containing electron-withdrawing and electron-donating functional groups

    SciTech Connect

    1996-10-01

    This study deals with the effects of chemical surface treatment of active carbons on their capacity to adsorb different organic pollutants in water. In particular, it explores the role of electrostatic adsorbate/adsorbent interactions and the consequences of the amphoteric nature of carbon surfaces. We contrast the behavior of chemically different carbons in adsorbing vastly different aromatic solutes. For example, nitrobenzene is a very weak Lewis acid that possesses the electron-withdrawing NO{sub 2} group, while aniline is a predominantly cationic species at pH < 4.6 that also possesses the electron-donating NH{sub 2} group.

  5. Kinetics of photoinhibition in hydroxylamine-extracted photosystem II membranes: Relevance to photoactivation and sites of electron donation

    SciTech Connect

    Blubaugh, D.J.; Cheniae, G.M. )

    1990-05-29

    Kinetic analyses were made of the effects of weak-light photoinhibition on the capacity of NH2OH-extracted photosystem II membranes to photooxidize the exogenous electron donors Mn2+, diphenylcarbazide, and I- or to assemble functional water-oxidizing complexes during photoactivation. The loss of capacity for photooxidation of the donors showed two first-order components (half-times of 2-3 min and 1-4 h) with relative amplitudes dependent on the donor, suggesting two photodamageable sites of electron donation (sites 1 and 2, respectively), a conclusion confirmed by analyses of velocity curves of electron donation by each donor. All of the donors appear to be oxidized preferentially by site 1 both at saturating and at limiting light intensity; however, the contribution by site 2 was nearly comparable in saturating light. Loss of photoactivation also exhibited biphasic kinetics, with components having half-times of approximately 0.8 and 3.2 min. The major component (t1/2 = 3.2 min) corresponded to loss of site 1; essentially no photoactivation was observed after its loss. From these and other analyses, we conclude (1) the relative contributions of site 1 and site 2 to the photooxidation of various exogenous electron donors is determined largely by the rates of equilibration of the donors with the two sites, and (2) only site 1 contributes to photoactivation of the water-oxidizing complex. Site 1 is attributed to tyrosine Z of the reaction center's D1 polypeptide. The molecular identity of site 2 is unknown but may be tyrosine D of the D2 polypeptide.

  6. Kinetics of photoinhibition in hydroxylamine-extracted photosystem II membranes: relevance to photoactivation and sites of electron donation.

    PubMed

    Blubaugh, D J; Cheniae, G M

    1990-05-29

    Kinetic analyses were made of the effects of weak-light photoinhibition on the capacity of NH2OH-extracted photosystem II membranes to photooxidize the exogenous electron donors Mn2+, diphenylcarbazide, and I- or to assemble functional water-oxidizing complexes during photoactivation. The loss of capacity for photooxidation of the donors showed two first-order components (half-times of 2-3 min and 1-4 h) with relative amplitudes dependent on the donor, suggesting two photodamageable sites of electron donation (sites 1 and 2, respectively), a conclusion confirmed by analyses of velocity curves of electron donation by each donor. All of the donors appear to be oxidized preferentially by site 1 both at saturating and at limiting light intensity; however, the contribution by site 2 was nearly comparable in saturating light. Loss of photoactivation also exhibited biphasic kinetics, with components having half-times of approximately 0.8 and 3.2 min. The major component (t1/2 = 3.2 min) corresponded to loss of site 1; essentially no photoactivation was observed after its loss. From these and other analyses, we conclude (1) the relative contributions of site 1 and site 2 to the photooxidation of various exogenous electron donors is determined largely by the rates of equilibration of the donors with the two sites, and (2) only site 1 contributes to photoactivation of the water-oxidizing complex. Site 1 is attributed to tyrosine Z of the reaction center's D1 polypeptide. The molecular identity of site 2 is unknown but may be tyrosine D of the D2 polypeptide. PMID:2198938

  7. Blood Donation Process

    MedlinePlus

    ... Blood Donation Information > Blood Donation Process Blood Donation Process Page Content Donating blood is a safe, simple, ... this test, as well as during the donation process, is sterile, used only once and then disposed. ...

  8. Hot electron plasmon-protected solar cell.

    PubMed

    Kong, J; Rose, A H; Yang, C; Wu, X; Merlo, J M; Burns, M J; Naughton, M J; Kempa, K

    2015-09-21

    A solar cell based on a hot electron plasmon protection effect is proposed and made plausible by simulations, non-local modeling of the response, and quantum mechanical calculations. In this cell, a thin-film, plasmonic metamaterial structure acts as both an efficient photon absorber in the visible frequency range and a plasmonic resonator in the IR range, the latter of which absorbs and protects against phonon emission the free energy of the hot electrons in an adjacent semiconductor junction. We show that in this structure, electron-plasmon scattering is much more efficient than electron-phonon scattering in cooling-off hot electrons, and the plasmon-stored energy is recoverable as an additional cell voltage. The proposed structure could become a prototype of a new generation of high efficiency solar cells. PMID:26406739

  9. IMIDAZOLE-BASED IONIC LIQUIDS FOR USE IN POLYMER ELECTROLYTE MEMBRANE FUEL CELLS: EFFECT OF ELECTRON-WITHDRAWING AND ELECTRON-DONATING SUBSTITUENTS

    SciTech Connect

    Chang, E.; Fu, Y.; Kerr, J.

    2009-01-01

    Current polymer electrolyte membrane fuel cells (PEMFCs) require humidifi cation for acceptable proton conductivity. Development of a novel polymer that is conductive without a water-based proton carrier is desirable for use in automobiles. Imidazole (Im) is a possible replacement for water as a proton solvent; Im can be tethered to the polymer structure by means of covalent bonds, thereby providing a solid state proton conducting membrane where the solvating groups do not leach out of the fuel cell. These covalent bonds can alter the electron availability of the Im molecule. This study investigates the effects of electron-withdrawing and electron-donating substituents on the conductivity of Im complexed with methanesulfonic acid (MSA) in the form of ionic liquids. Due to the changes in the electronegativity of nitrogen, it is expected that 2-phenylimidazole (2-PhIm, electron-withdrawing) will exhibit increased conductivity compared to Im, while 2-methylimidazole (2-MeIm, electron-donating) will exhibit decreased conductivity. Three sets of ionic liquids were prepared at defi ned molar ratios: Im-MSA, 2-PhIm-MSA, and 2-MeIm- MSA. Differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and 1H-NMR were used to characterize each complex. Impedance analysis was used to determine the conductivity of each complex. Both the 2-PhIm-MSA and 2-MeIm-MSA ionic liquids were found to be less conductive than the Im-MSA complex at base-rich compositions, but more conductive at acid-rich compositions. 1H-NMR data shows a downfi eld shift of the proton on nitrogen in 2-PhIm compared to Im, suggesting that other factors may diminish the electronic effects of the electron withdrawing group at base-rich compositions. Further studies examining these effects may well result in increased conductivity for Im-based complexes. Understanding the conductive properties of Im-derivatives due to electronic effects will help facilitate the development of a new electrolyte

  10. Superior Light-Harvesting Heteroleptic Ruthenium(II) Complexes with Electron-Donating Antennas for High Performance Dye-Sensitized Solar Cells.

    PubMed

    Chen, Wang-Chao; Kong, Fan-Tai; Li, Zhao-Qian; Pan, Jia-Hong; Liu, Xue-Peng; Guo, Fu-Ling; Zhou, Li; Huang, Yang; Yu, Ting; Dai, Song-Yuan

    2016-08-01

    Three heteroleptic polypyridyl ruthenium complexes, RC-41, RC-42, and RC-43, with efficient electron-donating antennas in the ancillary ligands were designed, synthesized, and characterized as sensitizers for dye-sensitized solar cell. All the RC dye sensitizers showed remarkable light-harvesting capacity and broadened absorption range. Significantly, RC-43 obtained the lower energy metal-ligand charge transfer (MLCT) band peaked at 557 nm with a high molar extinction coefficient of 27 400 M(-1) cm(-1). In conjunction with TiO2 photoanode of submicrospheres and iodide-based electrolytes, the DSSCs sensitizing with the RC sensitizers, achieved impressively high short-circuit current density (19.04 mA cm(-2) for RC-41, 19.83 mA cm(-2) for RC-42, and 20.21 mA cm(-2) for RC-43) and power conversion efficiency (10.07% for RC-41, 10.52% for RC-42, and 10.78% for RC-43). The superior performances of RC dye sensitizers were attributed to the enhanced light-harvesting capacity and incident-photon-to-current efficiency (IPCE) caused by the introduction of electron-donating antennas in the ancillary ligands. The interfacial charge recombination/regeneration kinetics and electron lifetime were further evaluated by the electrochemical impedance spectroscopy (EIS) and transient absorption spectroscopy (TAS). These data decisively revealed the dependences on the photovoltaic performance of ruthenium sensitizers incorporating electron-donating antennas. PMID:27409513

  11. Organ Donation

    MedlinePlus

    ... healthy organs and tissues from one person for transplantation into another. Experts say that the organs from one donor can save or help as many as 50 people. Organs you can donate include Internal organs: Kidneys, heart, liver, pancreas, intestines, lungs Skin Bone and bone marrow ...

  12. Transient (lightning) protection for electronic measurement devices

    SciTech Connect

    Black, L.L.

    1995-12-01

    Electronic measurement devices have become a major part of the oil and gas business today. All of these devices operate on an electrical voltage. Any voltage introduced into the system that is beyond the predetermined tolerance will cause degradation of performance or in some cases failure of the device. The extent of the damage depends upon the dielectric strength of the circuit in question and upon the available energy. As electronic measurement devices are further developed to incorporate more solid state circuitry and operate at lower voltage levels the more susceptible they become to transients. Along with transient protection, the user must also be concerned with intrinsic safety requirements of the device to be protected. The devices and techniques used to protect the equipment from transients do not, in all cases, guarantee the user certification for use in hazardous environments. As a note of reference, some of the techniques listed in this paper as examples would not be allowed in hazardous areas without the addition of other devices to further isolate or clamp the available energy to a safe level. In other words, as the industry moves forward to improve the overall accuracy of the measurement system and adds data availability via communication networks, the transient protection scheme must become more sophisticated.

  13. Donate Life America

    MedlinePlus

    ... Us News You Have the Power to Donate Life. Register as an Organ, Eye and Tissue Donor ... reach 30K milestone, thanks to increased donations Donate Life America Announces 2015 James S. Wolf, M.D., Courage ...

  14. Types of Blood Donations

    MedlinePlus

    ... may be an apheresis donation of plasma or plasma and platelets. The donation takes approximately 1 hour and 15 minutes. Call 1-800-RED-CROSS to find plasma apheresis donation opportunities near you. Learn More about ...

  15. Membrane-bound c-type cytochromes in Heliobacillus mobilis. In vivo study of the hemes involved in electron donation to the photosynthetic reaction center

    SciTech Connect

    Nitschke, W.; Kramer, D.M.; Liebl, U.

    1995-09-19

    The amount of heme per photosynthetic reaction center (RC) was examined in whole cells of Heliobacillus mobilis, and a stoichiometry of 5-6 hemes c and 1-3 hemes b per RC was found. Virtually the full complement of heme was seen to be functionally connected to the pool of electron donors to the photosynthetic RC. The kinetic parameters of electron transfer between reduced c-type hemes and the photooxidized primary donor P{sub 798}{sup +} were studied in whole cells and membrane fragments. The invivo half-times of electron donation (50% with t{sub 1/2}=110{mu}s, 50% with t{sub 1/2}=600 {mu}s) were seen to slow down to half-times in the range of several and several tens of milliseconds following disruption of cells. A severe conformational lateration or a change in the identity of the donating heme is discussed. Redox titrations of the flash-induced absorption changes performed on whole cells in the presence of mediators yielded the following redox midpoint potentials: P{sub 798}, E{sub m}=+240mV; heme c{sub 553}, E{sub m} = +190, +170, and +90 mV for the heme components oxidized after the first, second, and third flash, respectively. The results demonstrate that the pool of c{sub 553} hemes donating electrons to the RC is heterogeneous and that it consists of either several distinguishable cytochromes or multiheme cytochromes or both. The number of hemes reduced and the kinetics of heme rereduction after flash-induced oxidation were found to depend strongly on the degree of anaerobicity in the interior compartment for the cell. A model rationalizing the obtained results in terms of a set of differing redox components is proposed. 42 refs., 7 figs.

  16. Effectiveness of preoperative autologous blood donation for protection against allogeneic blood exposure in adult spinal deformity surgeries: a propensity-matched cohort analysis

    PubMed Central

    Kelly, Michael P.; Zebala, Lukas P.; Kim, Han Jo; Sciubba, Daniel M.; Smith, Justin S.; Shaffrey, Christopher I.; Bess, Shay; Klineberg, Eric; Mundis, Gregory; Burton, Douglas; Hart, Robert; Soroceanu, Alex; Schwab, Frank; Lafage, Virginie

    2015-01-01

    OBJECT The goal of this study was to examine the effectiveness of preoperative autologous blood donation (PABD) in adult spinal deformity (ASD) surgery. METHODS Patients undergoing single-stay ASD reconstructions were identified in a multicenter database. Patients were divided into groups according to PABD (either PABD or NoPABD). Propensity weighting was used to create matched cohorts of PABD and NoPABD patients. Allogeneic (ALLO) exposure, autologous (AUTO) wastage (unused AUTO), and complication rates were compared between groups. RESULTS Four hundred twenty-eight patients were identified as meeting eligibility criteria. Sixty patients were treated with PABD, of whom 50 were matched to 50 patients who were not treated with PABD (NoPABD). Nearly one-third of patients in the PABD group (18/60, 30%) did not receive any autologous transfusion and donated blood was wasted. In 6 of these cases (6/60, 10%), patients received ALLO blood transfusions without AUTO. In 9 cases (9/60, 15%), patients received ALLO and AUTO blood transfusions. Overall rates of transfusion of any type were similar between groups (PABD 70% [42/60], NoPABD 75% [275/368], p = 0.438). Major and minor in-hospital complications were similar between groups (Major PABD 10% [6/60], NoPABD 12% [43/368], p = 0.537; Minor PABD 30% [18/60], NoPABD 24% [87/368], p = 0.499). When controlling for potential confounders, PABD patients were more likely to receive some transfusion (OR 15.1, 95% CI 2.1–106.7). No relationship between PABD and ALLO blood exposure was observed, however, refuting the concept that PABD is protective against ALLO blood exposure. In the matched cohorts, PABD patients were more likely to sustain a major perioperative cardiac complication (PABD 8/50 [16%], NoPABD 1/50 [2%], p = 0.046). No differences in rates of infection or wound-healing complications were observed between cohorts. CONCLUSIONS Preoperative autologous blood donation was associated with a higher probability of

  17. [Post-mortem organ donation].

    PubMed

    Goroll, T; Gerresheim, G; Schaffartzik, W; Schwemmer, U

    2015-07-01

    In Germany approximately 3000 body organs are transplanted annually. In general, all artificially ventilated patients with diagnosed brain death are potential organ donors. All German hospitals are obliged to report potential organ donors and be actively involved in the organ donation process. These matters lie under the jurisdiction of the German transplantation act. An essential prerequisite for organ donation is the diagnosis of brain death according to the guidelines of the German Medical Association. Brain death is associated with complex pathophysiological changes in cardiopulmonary function as well as fluid, electrolyte and metabolic homeostasis. In the case of diagnosed brain death and with permission for organ donation, a precise organ-protective therapy is initiated, essentially focussing on optimal organ perfusion and oxygenation. The quality of organ protection has a direct influence on the outcome of transplantation. PMID:26174748

  18. Electronic overfill protection for crude oil transfer

    SciTech Connect

    Kilgore, D.R.; Miles, D.C.

    1995-12-31

    There are many considerations involved in the transfer of crude oil, but the most catastrophic consequences may come as the result of a spill during loading or unloading. The safety and well-being of personnel in the vicinity is of the utmost concern. Should one be fortunate enough that an explosion or fire is not the results of a spill, the one must contend with the dilemma of containment. Preserving environmental integrity is a subject that is high on everyone`s list. The phrase ``reportable spill`` can send chills up and down anyone`s back. The repercussions continue: Ground water contamination; Soil remediation; Regulatory fines and penalties; Litigation. And this is all topped off by the ``black eye`` that the company receives with the perception of the public. For these reasons, and more, the carriers of crude oil are choosing self imposed compliances to reduce the frequency of spills. Electronic Overfill Protection has been modified to meet the specific needs and requirements of the crude oil industry. Here, the authors will examine how this type of system evolved, how it functions, and where it may lead.

  19. Platelet Donation (Apheresis)

    MedlinePlus

    ... an appointment. You can also download the free Blood Donor App . Donating Blood Why Donate Blood? Eligibility Requirements ... Directed First Time Donors The Fear of Needles Blood Donor Community Real Stories SleevesUp Games Facebook Fanbox Avatars ...

  20. Organ Donation and Transplantation

    MedlinePlus

    ... my body to medical science? Can non-resident aliens donate and receive organs? Why should minorities be ... improving lives. Return to top Can non-resident aliens donate and receive organs? Non-resident aliens can ...

  1. Reduction of mitomycin C is catalysed by human recombinant NRH:quinone oxidoreductase 2 using reduced nicotinamide adenine dinucleotide as an electron donating co-factor

    PubMed Central

    Jamieson, D; Tung, A T Y; Knox, R J; Boddy, A V

    2006-01-01

    NRH:Quinone Oxidoreductase 2 (NQO2) has been described as having no enzymatic activity with nicotinamide adenine dinucleotide (NADH) or NADPH as electron donating cosubstrates. Mitomycin C (MMC) is both a substrate for and a mechanistic inhibitor of the NQO2 homologue NQO1. NRH:quinone oxidoreductase 2 catalysed the reduction of MMC at pH 5.8 with NADH as a co-factor. This reaction results in species that inhibit the NQO2-mediated metabolism of CB1954. In addition, MMC caused an increase in DNA cross-links in a cell line transfected to overexpress NQO2 to an extent comparable to that observed with an isogenic NQO1-expressing cell line. These data indicate that NQO2 may contribute to the metabolism of MMC to cytotoxic species. PMID:17031400

  2. Effect of electron-donating substituent groups on aromatic ring on photoluminescence properties of complexes of benzoic acid-functionalized polysulfone with Eu(III) ions.

    PubMed

    Gao, Baojiao; Chen, Lulu; Chen, Tao

    2015-10-14

    By molecular design and via polymer reactions, methoxybenzoic acid (MOBA) and hydroxybenzoic acid (HBA) were bonded onto the side chains of polysulfone (PSF) for preparing two benzoic acid-functionalized PSFs, PSF-MOBA and PSF-HBA, respectively. Based on full characterization of their structures, the two macromolecule ligands were made to coordinate to Eu(3+) ions, and two binary polymer-rare earth complexes, PSF-(MOBA)3-Eu(III) and PSF-(HBA)3-Eu(III), were obtained. At the same time, using phenanthroline (Phen) as a second small-molecule ligand, the corresponding two ternary complexes, PSF-(MOBA)3-Eu(III)-Phen1 and PSF-(HBA)3-Eu(III)-Phen1, were also prepared. The photo physical behaviors of these complexes were examined in depth, and the luminescent properties of these prepared polymer-rare earth complexes were mainly investigated. The experimental results show that the two electron-donating substituent groups on the aromatic ring of the bonded benzoic acid significantly affect the luminescence properties of these complexes of benzoic acid-functionalized PSF and Eu(III) ions, and they can effectively strengthen the fluorescence emission intensities of the complexes. The possible reason is that through the p-π conjugative effect, the two electron-donating substituent groups can remarkably decline the triplet state energy levels of the bonded ligand MOBA and HBA, and strengthen the matching degree of energy between the triplet state energy level of the ligand and the resonant energy level of Eu(III) ions, resulting in the enhancement of fluorescence emission intensities of the complexes. Besides, the fluorescence emissions of the binary complexes are stronger than those of the corresponding ternary complexes because of the synergistic coordination effect of Phen with the macromolecular ligand. PMID:26355714

  3. Platelet Donation (Apheresis)

    MedlinePlus

    ... may be ideal for a simultaneous platelet and plasma donation. Anyone in need can receive your plasma, it is universal. Only 4% of the U.S. ... can donate up to 24 times per year. Plasma can be collected simultaneously with a platelet donation. ...

  4. High performance protection circuit for power electronics applications

    NASA Astrophysics Data System (ADS)

    Tudoran, Cristian D.; Dǎdârlat, Dorin N.; Toşa, Nicoleta; Mişan, Ioan

    2015-12-01

    In this paper we present a high performance protection circuit designed for the power electronics applications where the load currents can increase rapidly and exceed the maximum allowed values, like in the case of high frequency induction heating inverters or high frequency plasma generators. The protection circuit is based on a microcontroller and can be adapted for use on single-phase or three-phase power systems. Its versatility comes from the fact that the circuit can communicate with the protected system, having the role of a "sensor" or it can interrupt the power supply for protection, in this case functioning as an external, independent protection circuit.

  5. High performance protection circuit for power electronics applications

    SciTech Connect

    Tudoran, Cristian D. Dădârlat, Dorin N.; Toşa, Nicoleta; Mişan, Ioan

    2015-12-23

    In this paper we present a high performance protection circuit designed for the power electronics applications where the load currents can increase rapidly and exceed the maximum allowed values, like in the case of high frequency induction heating inverters or high frequency plasma generators. The protection circuit is based on a microcontroller and can be adapted for use on single-phase or three-phase power systems. Its versatility comes from the fact that the circuit can communicate with the protected system, having the role of a “sensor” or it can interrupt the power supply for protection, in this case functioning as an external, independent protection circuit.

  6. Combination of UV absorbance and electron donating capacity to assess degradation of micropollutants and formation of bromate during ozonation of wastewater effluents.

    PubMed

    Chon, Kangmin; Salhi, Elisabeth; von Gunten, Urs

    2015-09-15

    In this study, the changes in UV absorbance at 254 nm (UVA254) and electron donating capacity (EDC) were investigated as surrogate indicators for assessing removal of micropollutants and bromate formation during ozonation of wastewater effluents. To measure the EDC, a novel method based on size exclusion chromatography followed by a post-column reaction was developed and calibrated against an existing electrochemical method. Low specific ozone doses led to a more efficient abatement of EDC than of UVA254. This was attributed to the abatement of phenolic moieties in the dissolved organic matter (DOM), which lose their EDC upon oxidation, but are partially transformed into quinones, which still absorb in the measured UV range. For higher specific ozone doses, the relative EDC abatement was lower than the relative UVA abatement, which can be explained by the oxidation of UV absorbing moieties (e.g. non-activated aromatic compounds), which contribute less to EDC. The abatement of the selected micropollutants (i.e., 17α-ethinylestradiol (EE2), carbamazepine (CBZ), atenolol (ATE), bezafibrate (BZF), ibuprofen (IBU), and p-chlorobenzoic acid (pCBA)) varied significantly depending on their reactivity with ozone in the examined specific ozone dose range of 0-1.45 mgO3/mgDOC. The decrease of EE2 and CBZ with high ozone reactivity was linearly proportional to the reduction of the relative residuals of UVA254 and EDC. The abatement of ATE, BZF, IBU, and pCBA with intermediate to low ozone reactivities was not significant in a first phase (UVA254/UVA254,0 = 1.00-0.70; EDC/EDC0 = 1.00-0.56) while their abatement was more efficient than the degradation of the relative residual UVA254 and much more noticeable than the degradation of the relative residual EDC in a second phase (UVA254/UVA254,0 = 0.70-0.25; EDC/EDC0 = 0.56-0.25) because the partially destroyed UV absorbing and electron donating DOM moieties become recalcitrant to ozone attack. Bromate formation was

  7. Balancing Good Intentions: Protecting the Privacy of Electronic Health Information

    ERIC Educational Resources Information Center

    McClanahan, Kitty

    2008-01-01

    Electronic information is a vital but complex component in the modern health care system, fueling ongoing efforts to develop a universal electronic health record infrastructure. This innovation creates a substantial tension between two desirable values: the increased quality and utility of patient medical records and the protection of the privacy…

  8. Guidelines for drug donations.

    PubMed Central

    Hogerzeil, H. V.; Couper, M. R.; Gray, R.

    1997-01-01

    Drug donations are usually given in response to acute emergencies, but they can also be part of development aid. Donations may be given directly by governments, by non-governmental organisations, as corporate donations (direct or through private voluntary organisations), or as private donations to single health facilities. Although there are legitimate differences between these donations, basic rules should apply to them all. This common core of "good donation practice" is the basis for new guidelines which have recently been issued by the World Health Organisation after consultation with all relevant United Nations agencies, the Red Cross, and other major international agencies active in humanitarian emergency relief. This article summarises the need for such guidelines, the development process, the core principles, and the guidelines themselves and gives practical advice to recipients and donor agencies. PMID:9116555

  9. Systematic analysis of the demetalation kinetics of zinc chlorophyll derivatives possessing different substituents at the 3-position: effects of the electron-withdrawing and electron-donating strength of peripheral substituents.

    PubMed

    Saga, Yoshitaka; Kobashiri, Yuta; Sadaoka, Kana

    2013-01-01

    Removal of the central metal from chlorophyll (Chl) molecules is biologically important in terms of production of the primary electron acceptors in photosystem-II photosynthetic reaction centers and the early stage in Chl degradation. The physicochemical properties on demetalation of chlorophyllous pigments are useful in the understanding of such reaction mechanisms in photosynthetic organisms. Here we analyzed the demetalation kinetics of a series of Zn-Chl derivatives with a systematic variation in the electron-withdrawing and -donating substituents at the 3-position of the chlorin macrocycle under acidic conditions to elucidate thoroughly the substitution effects on the demetalation properties of chlorophyllous pigments. Dehydrogenation of the aliphatic group (CH(2)CH(3) → CH═CH(2) → C≡CH) at the 3-position slowed the removal of the central zinc from the chlorin macrocycle. The gradual decrease in the demetalation rate constants of the three zinc chlorins originates from differences in the electron-withdrawing strength of the ethyl, vinyl, and ethynyl groups directly linked to the chlorin π macrocycle. Reduction of the 3(1)-carbonyl groups significantly increased the demetalation rate constants, and the relative ratios of the demetalation rate constants of the zinc chlorins possessing a carbonyl group to those possessing the corresponding hydroxy group were analogous in the cases of 3-formyl- and 3-acetyl-zinc chlorins. The demetalation rate constants of the seven Zn-Chl derivatives possessing various electron-withdrawing and -donating groups exhibited good correlation with the Hammett σ parameters of the 3-position substituents. PMID:23230816

  10. Bone marrow (stem cell) donation

    MedlinePlus

    Stem cell transplant; Allogeneic-donation ... There are two types of bone marrow donation: Autologous bone marrow transplant is when people donate their own bone marrow. "Auto" means self. Allogenic bone marrow transplant is when another person ...

  11. Donating Peripheral Blood Stem Cells

    MedlinePlus

    ... Ways to give How your gift saves lives Donate cord blood Cord blood is changing lives Federal cord blood ... Cord blood options Sibling directed donation How to donate cord blood Participating hospitals Cord blood FAQs Learn if you ...

  12. Agent-based copyright protection architecture for online electronic publishing

    NASA Astrophysics Data System (ADS)

    Yi, Xun; Kitazawa, S.; Okamoto, Ejii; Wang, Xiao F.; Lam, KwokYan; Tu, S.

    1999-04-01

    Electronic publishing faces one major technical and economic challenge, i.e., how to prevent individuals from easily copying and illegally distributing electronic documents. Conventional cryptographic systems permit only valid key- holders access to encrypted data, but once such data is decrypted there is no way to track its reproduction or retransmission. Therefore, they provide little protection against data privacy, in which a publisher is confronted with unauthorized reproduction of information. In this paper, we explore the use of intelligent agent, digital watermark and cryptographic techniques to discourage the distribution of illegal electronic copies and propose an agent-based strategy to protect the copyright of on-line electronic publishing. In fact, it is impossible to develop an absolute secure copyright protection architecture for on-line electronic publishing which can prevent a malicious customer from spending a great deal of efforts on analyzing the software and finally obtaining the plaintext of the encrypted electronic document. Our work in this paper aims at making the value of analyzing agent and removing watermark to be much greater than that of the electronic document itself.

  13. Electronic Health Record in Italy and Personal Data Protection.

    PubMed

    Bologna, Silvio; Bellavista, Alessandro; Corso, Pietro Paolo; Zangara, Gianluca

    2016-06-01

    The present article deals with the Italian Electronic Health Record (hereinafter EHR), recently introduced by Act 221/2012, with a specific focus on personal data protection. Privacy issues--e.g., informed consent, data processing, patients' rights and minors' will--are discussed within the framework of recent e-Health legislation, national Data Protection Code, the related Data Protection Authority pronouncements and EU law. The paper is aimed at discussing the problems arising from a complex, fragmentary and sometimes uncertain legal framework on e-Health. PMID:27491249

  14. Unexpected formation of π-expanded isoquinoline from anthracene possessing four electron-donating groups via the Duff reaction.

    PubMed

    Węcławski, Marek K; Deperasińska, Irena; Leniak, Arkadiusz; Banasiewicz, Marzena; Kozankiewicz, Bolesław; Gryko, Daniel T

    2016-08-01

    New synthetic methods leading towards π-expanded heterocycles are sought after mainly due to their promising opto-electronic properties. Subjecting 1,5,9,10-tetramethoxyanthracene to the modern Duff reaction conditions led to the formation of a compound possessing the 2-azabenzoanthrone (dibenzo[de,h]isoquinolin-7-on) skeleton instead of the expected dialdehyde. This non-typical course of reaction can be rationalized by the double electrophilic aromatic substitution at two neighboring electron-rich positions of anthracene followed by oxidation of the resulting intermediate to form a pyridine ring. Optical studies supported by the quantum chemistry calculations indicated the lack of excited-state intramolecular proton transfer (ESIPT); for energy reasons, only one tautomeric form, with a hydrogen atom bonded to one of the two nearby oxygen atoms, was populated in the electronic ground S0 and in the excited S1 states. Nonradiative depopulation of the S1 state proceeded via internal conversion stimulated by the presence of the low frequency vibrational modes. Our serendipitous discovery represents the most complex case of rearrangement of aromatic compounds under Duff reaction conditions and could help to design analogous processes. At the same time this is the simplest method for the synthesis of derivatives of 2-azabenzoanthrone. PMID:27367169

  15. Personalised electronic messages to improve sun protection in young adults.

    PubMed

    Mair, Sarah; Soyer, H Peter; Youl, Philippa; Hurst, Cameron; Marshall, Alison; Janda, Monika

    2012-07-01

    We studied the acceptability and feasibility of delivering sun protection messages via electronic media such as short message services (SMS) to people aged 18-40 years. An online survey was conducted using a pre-established panel of volunteers. We compared the characteristics of those who indicated that they would like to be alerted to the UV index, with those who would not, using bivariate logistic regression. Characteristics found to be associated with a desire to receive such advice were entered into a multivariate logistic regression analysis. The median age of the 141 participants was 34 years. Overall, 80% of participants agreed that they would like to receive some form of sun protection advice. Of these, 20% preferred to receive it via SMS and 42% via email. Willingness to receive electronic messages about the UV index was associated with being unsure about whether a suntanned person would look healthy and greater use of sun protection in the past. Careful attention to message framing and timing of message delivery, and focus on the short-term effects of sun exposure such as sunburn and skin ageing should increase the acceptability of such messages to young people. Sun protection messages delivered to young adults via electronic media appear to be feasible and acceptable. PMID:22302765

  16. Tryptophan promotes charitable donating

    PubMed Central

    Steenbergen, Laura; Sellaro, Roberta; Colzato, Lorenza S.

    2014-01-01

    The link between serotonin (5-HT) and one of the most important elements of prosocial behavior, charity, has remained largely uninvestigated. In the present study, we tested whether charitable donating can be promoted by administering the food supplement L-Tryptophan (TRP), the biochemical precursor of 5-HT. Participants were compared with respect to the amount of money they donated when given the opportunity to make a charitable donation. As expected, compared to a neutral placebo, TRP appears to increase the participants’ willingness to donate money to a charity. This result supports the idea that the food we eat may act as a cognitive enhancer modulating the way we think and perceive the world and others. PMID:25566132

  17. Blood Transfusion and Donation

    MedlinePlus

    ... the blood transfusion. To keep blood safe, blood banks carefully screen donated blood. The risk of catching ... or more times before the surgery. A blood bank will store your blood for your use. NIH: ...

  18. Blood donation before surgery

    MedlinePlus

    ... of donor blood. Many communities have a blood bank where healthy people can donate blood. This blood ... to arrange with your hospital or local blood bank before your surgery to have directed donor blood. ...

  19. FDA Recommends All Blood Donations Be Tested for Zika

    MedlinePlus

    ... FDA Recommends All Blood Donations Be Tested for Zika Updated guidance provides further protection for U.S. blood ... entire blood supply be routinely screened for the Zika virus. In February, the FDA recommended testing of ...

  20. National Organ and Tissue Donation Initiative

    MedlinePlus

    ... and Terms Get Involved Workplace Partnership for Life Social Media Outreach Materials National Donation Events Donation Organizations Sign ... can help spread the message about signing up. Social Media Facebook YouTube National Donation Events Donation Organizations Find ...

  1. Synthesis and crystal structures of lanthanide 4-benzyloxy benzoates: influence of electron-withdrawing and electron-donating groups on luminescent properties.

    PubMed

    Sivakumar, Sarika; Reddy, M L P; Cowley, Alan H; Vasudevan, Kalyan V

    2010-01-21

    Three new 4-benzyloxy benzoic acid derivatives [4-benzyloxy benzoic acid = HL1; 3-methoxy-4-benzyloxy benzoic acid = HL2; 3-nitro-4-benzyloxy benzoic acid = HL3] have been employed as ligands for the support of six lanthanide coordination compounds [Tb(3+) = 1-3; Eu(3+) = 4-6] with the aim of testing the influence of electron releasing (-OMe) or electron withdrawing (-NO(2)) substituents on the photophysical properties. The new complexes have been characterized by a variety of spectroscopic techniques and two of the Tb(3+) complexes [1 and 2] have been structurally authenticated by single-crystal X-ray diffraction. Compounds 1 and 2 crystallize in the monoclinic space group P21/n. The molecular structure of 1 consists of homodinuclear species that are bridged by two oxygen atoms from two benzoate ligands [corrected].In the case of 1, the carboxylate ligands coordinate to the central Tb(3+) ion in bidentate chelating and bidentate bridging modes. By contrast, the X-ray structure of 2 reveals that each Tb3+ ion is connected to two neighboring ions by four methoxy substituted benzoates via the carboxylate groups in bridging mode to form an infinite one-dimensional coordination polymer [corrected]. Examination of the packing diagrams for 1 and 2 revealed the presence of a one-dimensional molecular array that is held together by intermolecular hydrogen-bonding interactions. The incorporation of an electron-releasing substituent on position 3 of 4-benzyloxy benzoic acid increases the electron density of the ligand and consequently improves the photoluminescence of the Tb(3+) complexes. On the other hand, the presence of an electron-withdrawing group at this position dramatically decreases the overall sensitization efficiency of the Tb(3+)-centered luminescence due to dissipation of the excitation energy by means of a pi*-n transition of the NO(2) substituent along with the participation of the ILCT bands. The weaker photoluminescence of the Eu(3+) complexes is

  2. Deceased Organ Donation.

    PubMed

    Israni, A K; Zaun, D; Bolch, C; Rosendale, J D; Snyder, J J; Kasiske, B L

    2016-01-01

    SRTR uses data collected by OPTN to calculate metrics such as donation/conversion rate, organ yield, and rate of organs recovered for transplant but not transplanted. In 2014, 9252 eligible deaths were reported by organ procurement organizations, a slight increase from 8944 in 2012, and the donation/conversation rate was 73.4 eligible donors per 100 eligible deaths, a slight increase from 71.3 in 2013. Some metrics show variation across organ procurement organizations, suggesting that sharing best practices could lead to gains in efficiency and organ retrieval. PMID:26755269

  3. Lightning protection of full authority digital electronic systems

    NASA Technical Reports Server (NTRS)

    Crofts, David

    1991-01-01

    Modern electronic systems are vulnerable to transient and they now provide safety critical functions such as full authority digital electronic control (FADEC) units for fly by wire aircraft. Of the traditional suppression technologies available diodes have gained the wider acceptance, however, they lack the current handling capacity to meet existing threat levels. The development of high speed fold back devices where, at a specified voltage, the off state resistance switches to a very low on state one has provided the equivalent to a semiconductor spark gap. The size of the technology enables it to be integrated into connectors of interconnection cables. To illustrate the performance the technology was developed to meet the Lightning Protection requirements for FADEC units within aeroengines. Work was also carried out to study switching behavior with the waveform 5, the 500 us, 10 kA pulse applied to cable assemblies. This test enabled all the switches in a connector to be fired simultaneously.

  4. Controversies in kidney paired donation.

    PubMed

    Gentry, Sommer E; Montgomery, Robert A; Segev, Dorry L

    2012-07-01

    Kidney paired donation represented 10% of living kidney donation in the United States in 2011. National registries around the world and several separate registries in the United States arrange paired donations, although with significant variations in their practices. Concerns about ethical considerations, clinical advisability, and the quantitative effectiveness of these approaches in paired donation result in these variations. For instance, although donor travel can be burdensome and might discourage paired donation, it was nearly universal until convincing analysis showed that living donor kidneys can sustain many hours of cold ischemia time without adverse consequences. Opinions also differ about whether the last donor in a chain of paired donation transplants initiated by a nondirected donor should donate immediately to someone on the deceased donor wait-list (a domino or closed chain) or should be asked to wait some length of time and donate to start another sequence of paired donations later (an open chain); some argue that asking the donor to donate later may be coercive, and others focus on balancing the probability that the waiting donor withdraws versus the number of additional transplants if the chain can be continued. Other controversies in paired donation include simultaneous versus nonsimultaneous donor operations, whether to enroll compatible pairs, and interactions with desensitization protocols. Efforts to expand public awareness of and participation in paired donation are needed to generate more transplant opportunities. PMID:22732046

  5. Types of Blood Donations

    MedlinePlus

    ... laboratory and separated into components (red blood cells, plasma and sometimes into platelets and cryoprecipitate). After processing, the red blood cells can be stored for up to 42 days. Apheresis An apheresis blood donation is one where the blood goes through a special machine ...

  6. A systematic review and meta-analysis of antecedents of blood donation behavior and intentions.

    PubMed

    Bednall, Timothy C; Bove, Liliana L; Cheetham, Ali; Murray, Andrea L

    2013-11-01

    , minimizing the risk of adverse reactions and enacting re-recruitment policies for temporarily deferred donors will help protect future donation behavior. Implications of these findings for blood collection agencies and researchers are discussed. PMID:24034955

  7. Blood Donation by Elderly Repeat Blood Donors

    PubMed Central

    Zeiler, Thomas; Lander-Kox, Jutta; Alt, Timo

    2014-01-01

    Summary Background Upper age limits for blood donors are intended to protect elderly blood donors from donor reactions. However, due to a lack of data about adverse reactions in elderly blood donors, upper age limits are arbitrary and vary considerably between different countries. Methods Here we present data from 171,231 voluntary repeat whole blood donors beyond the age of 68 years. Results Blood donations from repeat blood donors beyond the age of 68 years increased from 2,114 in 2005 to 38,432 in 2012 (from 0,2% to 4.2% of all whole blood donations). Adverse donor reactions in repeat donors decreased with age and were lower than in the whole group (0.26%), even in donors older than 71 years (0.16%). However, from the age of 68 years, the time to complete recovery after donor reactions increased. Donor deferrals were highest in young blood donors (21.4%), but increased again in elderly blood donors beyond 71 years (12.6%). Conclusion Blood donation by regular repeat blood donors older than 71 years may be safely continued. However, due to a lack of data for donors older than 75 years, blood donation in these donors should be handled with great caution. PMID:25254019

  8. Pediatric Organ Donation: What Factors Most Influence Parents’ Donation Decisions?

    PubMed Central

    Rodrigue, James R.; Cornell, Danielle L.; Howard, Richard J.

    2008-01-01

    Objective To identify factors that influence parents’ decisions when asked to donate a deceased child’s organs. Design Cross-sectional design with data collection via structured telephone interviews. Setting and Participants Seventy-four parents (49 donors, 25 non-donors) of donor-eligible deceased children who were previously approached by coordinators from one organ procurement organization (OPO) in the southeastern USA. Main Results Multivariate analyses showed that organ donation was more likely when the parent was a registered organ donor (OR=1.4, CI=1.1, 2.7), the parent had favorable organ donation beliefs (OR=5.5, CI=2.7, 12.3), the parent was exposed to organ donation information prior to the child’s death (OR = 2.6, CI = 1.7, 10.3), a member of the child’s healthcare team first mentioned organ donation (OR=1.4, CI=1.2, 3.7), the requestor was perceived as sensitive to the family’s needs (OR=0.4, CI=0.2, 0.7), the family had sufficient time to discuss donation (OR=5.2, CI=1.4, 11.6), and family members were in agreement about donation (OR=2.8, CI=1.3, 5.2). Conclusions This study identifies several modifiable variables that influence the donation decision-making process for parents. Strategies to facilitate targeted organ donation education and higher consent rates are discussed. PMID:18477931

  9. Solid organ donation and transplantation.

    PubMed

    Furlow, Bryant

    2012-01-01

    Medical imaging plays a key role in solid organ donation and transplantation. In addition to confirming the clinical diagnosis of brain death, imaging examinations are used to assess potential organ donors and recipients, evaluate donated organs, and monitor transplantation outcomes. This article introduces the history, biology, ethics, and institutions of organ donation and transplantation medicine. The article also discusses current and emerging imaging applications in the transplantation field and the controversial role of neuroimaging to confirm clinically diagnosed brain death. PMID:22461345

  10. Electron transport in molecular junctions with graphene as protecting layer

    SciTech Connect

    Hüser, Falco; Solomon, Gemma C.

    2015-12-07

    We present ab initio transport calculations for molecular junctions that include graphene as a protecting layer between a single molecule and gold electrodes. This vertical setup has recently gained significant interest in experiment for the design of particularly stable and reproducible devices. We observe that the signals from the molecule in the electronic transmission are overlayed by the signatures of the graphene sheet, thus raising the need for a reinterpretation of the transmission. On the other hand, we see that our results are stable with respect to various defects in the graphene. For weakly physiosorbed molecules, no signs of interaction with the graphene are evident, so the transport properties are determined by offresonant tunnelling between the gold leads across an extended structure that includes the molecule itself and the additional graphene layer. Compared with pure gold electrodes, calculated conductances are about one order of magnitude lower due to the increased tunnelling distance. Relative differences upon changing the end group and the length of the molecule on the other hand, are similar.

  11. Electron transport in molecular junctions with graphene as protecting layer

    NASA Astrophysics Data System (ADS)

    Hüser, Falco; Solomon, Gemma C.

    2015-12-01

    We present ab initio transport calculations for molecular junctions that include graphene as a protecting layer between a single molecule and gold electrodes. This vertical setup has recently gained significant interest in experiment for the design of particularly stable and reproducible devices. We observe that the signals from the molecule in the electronic transmission are overlayed by the signatures of the graphene sheet, thus raising the need for a reinterpretation of the transmission. On the other hand, we see that our results are stable with respect to various defects in the graphene. For weakly physiosorbed molecules, no signs of interaction with the graphene are evident, so the transport properties are determined by offresonant tunnelling between the gold leads across an extended structure that includes the molecule itself and the additional graphene layer. Compared with pure gold electrodes, calculated conductances are about one order of magnitude lower due to the increased tunnelling distance. Relative differences upon changing the end group and the length of the molecule on the other hand, are similar.

  12. Electron transport in molecular junctions with graphene as protecting layer.

    PubMed

    Hüser, Falco; Solomon, Gemma C

    2015-12-01

    We present ab initio transport calculations for molecular junctions that include graphene as a protecting layer between a single molecule and gold electrodes. This vertical setup has recently gained significant interest in experiment for the design of particularly stable and reproducible devices. We observe that the signals from the molecule in the electronic transmission are overlayed by the signatures of the graphene sheet, thus raising the need for a reinterpretation of the transmission. On the other hand, we see that our results are stable with respect to various defects in the graphene. For weakly physiosorbed molecules, no signs of interaction with the graphene are evident, so the transport properties are determined by offresonant tunnelling between the gold leads across an extended structure that includes the molecule itself and the additional graphene layer. Compared with pure gold electrodes, calculated conductances are about one order of magnitude lower due to the increased tunnelling distance. Relative differences upon changing the end group and the length of the molecule on the other hand, are similar. PMID:26646877

  13. Obstacles to organ donation.

    PubMed

    Wakeford, R E; Stepney, R

    1989-05-01

    Attitudes towards transplantation were investigated in national surveys of the general public (n = 1471), the medical profession (n = 590) and key clinical staff in units referring potential organ donors (n = 380). A clear majority of doctors would like to see more transplants. Only 16 per cent of doctors opposed them on cost grounds, and a 50 per cent 5-year survival rate is seen as more than adequate clinical justification. However, doctors are less supportive of liver and heart grafts than of kidney and cornea grafts. Few lay people would refuse donation of specific organs, but 30 per cent worry that doctors might be pressured into removal of organs when they are not sure the patient is dead. Religious or moral objection is rare. Intensive care unit staff felt the most important factor restricting organ harvest in their own units was dislike of adding to relatives' distress, followed by lack of training in approaching relatives and adverse media publicity. Only 11 per cent thought reservations on brain stem death a likely or possible influence. Enhanced public awareness of the need for transplants was seen as the most important means of increasing organ harvest. Required request would be controversial and perhaps impossible to implement. We conclude that the time, effort and expense involved in potential organ donation do not play a substantial part in limiting referral. Neither do reservations about brain stem death. Increased training of staff (both in communication skills and in the professional responsibility to encourage donation) and greater public awareness are seen as the twin foundations of a realistic approach to enhancing referral. PMID:11644374

  14. [Organ donation after circulatory death].

    PubMed

    de Jonge, J; Kalisvaart, M; van der Hoeven, M; Epker, J; de Haan, J; IJzermans, J N M; Grüne, F

    2016-02-01

    Approximately 17 million inhabitants live in the Netherlands. The number of potential organ donors in 1999 was the lowest in Europe with only 10 donors per million inhabitants. Medical associations, public health services, health insurance companies and the government had to find common solutions in order to improve organ allocation, logistics of donations and to increase the number of transplantations. After a prolonged debate on medical ethical issues of organ transplantation, all participants were able to agree on socio-medico-legal regulations for organ donation and transplantation. In addition to improving the procedure for organ donation after brain death (DBD) the most important step was the introduction of organ donation after circulatory death (DCD). Measures such as the introduction of a national organ donor database, improved information to the public, further education on intensive care units (ICU), guidelines for end of life care on the ICU, establishment of transplantation coordinators on site, introduction of autonomous explantation teams and strict procedures on the course of organ donations, answered many practical issues about logistics and responsibilities for DBD and DCD. In 2014 the number of postmortem organ donations rose to 16.4 per million inhabitants. Meanwhile, up to 60 % of organ donations in the Netherlands originate from a DCD procedure compared to approximately 10 % in the USA. This overview article discusses the developments and processes of deceased donation in the Netherlands after 15 years of experience with DCD. PMID:26810404

  15. Organ donation as gift exchange.

    PubMed

    Vernale, C; Packard, S A

    1990-01-01

    Organ donation, considered by sociologists as a type of gift exchange, involves moral, social, psychological, religious and legal issues. This gift exchange paradigm can be used as a framework to understand donor and recipient issues, cadaveric organ donation and the importance of the role of nurses during organ procurement. PMID:2292445

  16. Paid donation: a global view.

    PubMed

    Ghahramani, Nasrollah; Rizvi, S Adibul Hasan; Padilla, Benita

    2012-07-01

    Paying for kidney or other organ donation has lead to heated debates about donor and recipient welfare. Many have argued that paying for donation leads to coercion and exploitation of the poor, and, in the end, produces more harm than good. Others have said that payment helps the poor, and we should all have sovereignty over our bodies and, thus, should be allowed to donate for remuneration. Although World Health Organizations and governments in many countries have now banned the process of paying for donation, there is still ongoing payment legally and illegally. Thus, this timely set of three articles from Iran, Pakistan, and the Philippines, where paid donation has been extensively performed, will allow the reader to decide for themselves whether the benefits and/or harms of this practice are now clear. PMID:22732047

  17. [Donation of blood components].

    PubMed

    Ladrón Llorente, Yolanda; Rández Alvero, Mónica; Carrascosa Ridruejo, Ana Isabel; Bregua García, Judith; Blanco Sotés, Carmelo; Calavia Lacarra, Jesús

    2004-06-01

    The donation of blood by means of aphaeresis by means of a cellular separator is a procedure through which one obtains blood components in the most efficient manner, yielding the best quality in the final product although this procedure requires special characteristics on behalf of the donor and consequently has a higher cost. The authors have analyzed the characteristics of 81 donors who used this procedure and who voluntarily came to our blood bank over a 17 month period from January 2002 until May 2003; 287 such procedures were carried out. The quality of the product obtained, as a benefit for the possible receptor, compensates the greater dedication by the donor and the high cost of this technique. PMID:15315098

  18. Sperm donation in Israel.

    PubMed

    Mor-Yosef, S; Schenker, J G

    1995-04-01

    Science and technology in the field of human reproduction present new legal, ethical and religious questions which do not always have immediate answers. The first step in the rapidly developed field of reproductive technology was the use of sperm donation (artificial insemination by donor, AID) and the establishment of sperm banks. The state of Israel faced these problems when the regulations for sperm donation were discussed. The fact that the main holy places for the three monotheistic religions are in Israel directly influences the make-up of the population constituents. Therefore, besides a majority of secular people, a high percentage of the population of Israel is very religious: Jews, Moslems and Christians. Thus any resolution relating to AID should take this demographic combination into account. The practice of AID is opposed by the different monotheistic religions. To avoid the conflict between secular and religious people, and between the different religions' perspectives, the legal problem of AID in Israel was solved not by laws but by regulations which were published by the Ministry of Health. The main idea behind this attitude is that the state and its authorities should not and do not deal with ethical or religious questions. Thus, the decision was left to the couples and to the donors. The regulations address technical requirements, health problems and confidential issues concerning the couple, the donor and the child. In this paper we present the different views relating to these problems as perceived by the different religions, and describe the solution that was accepted by the Israeli Ministry of Health. PMID:7650152

  19. A practical Israeli strategy for appealing for organ donation.

    PubMed

    Ashkenazi, Tamar; Klein, Moti

    2013-06-01

    CONTEXT-Most reports on organ donation have been related to the importance of support for families, explanations of brain death, and the appeal for organ donation. In contrast, no reports have addressed organ donation from the perspective of intervention in cases of "sudden mourning" and the practical aspects of how to facilitate donation in such cases. OBJECTIVE-To develop a specific strategy for professional intervention in cases of imminent death to bring the family to a state of cognitive and emotional preparedness that will enable them to accept the tragic news, donate organs, and then take leave of the deceased. METHOD-The strategy presented here was developed on the basis of the records of donor coordinators who documented their interaction with families; consultations with professionals in the fields of marketing, persuasion, and negotiating; research conducted on families who did or did not donate organs; and statements made by family members of donors in focus and support groups in more than 10 years. RESULTS-The strategic approach includes early-stage rules such as staff self-awareness, and then later, critical stages of the process that take place before and at the time of determination of brain death: preparation for and the notification of death itself and the request for organ donation, including persuasion skills, coping with resistance and expressions of anger, and physical leave-taking from the deceased. CONCLUSIONS-The flexible, strategic approach set out here is designed to maximize the chances of procuring organ donation while protecting the family's rights and welfare. PMID:23782666

  20. 32 CFR 553.6 - Donations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Donations. 553.6 Section 553.6 National Defense... NATIONAL CEMETERIES § 553.6 Donations. (a) Policy. Under Department of the Army policy, proffered donations... for the donation or gift. (2) Delivery is made to the cemetery or to another point designated by...

  1. 32 CFR 553.6 - Donations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Donations. 553.6 Section 553.6 National Defense... NATIONAL CEMETERIES § 553.6 Donations. (a) Policy. Under Department of the Army policy, proffered donations... for the donation or gift. (2) Delivery is made to the cemetery or to another point designated by...

  2. 32 CFR 553.6 - Donations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Donations. 553.6 Section 553.6 National Defense... NATIONAL CEMETERIES § 553.6 Donations. (a) Policy. Under Department of the Army policy, proffered donations... for the donation or gift. (2) Delivery is made to the cemetery or to another point designated by...

  3. 32 CFR 553.6 - Donations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Donations. 553.6 Section 553.6 National Defense... NATIONAL CEMETERIES § 553.6 Donations. (a) Policy. Under Department of the Army policy, proffered donations... for the donation or gift. (2) Delivery is made to the cemetery or to another point designated by...

  4. 32 CFR 553.6 - Donations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Donations. 553.6 Section 553.6 National Defense... NATIONAL CEMETERIES § 553.6 Donations. (a) Policy. Under Department of the Army policy, proffered donations... for the donation or gift. (2) Delivery is made to the cemetery or to another point designated by...

  5. 14 CFR 25.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... time the airplane is exposed to lightning; and (2) The system automatically recovers normal...

  6. 14 CFR 29.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... after the time the rotorcraft is exposed to lightning; and (2) The system automatically recovers...

  7. 14 CFR 29.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... after the time the rotorcraft is exposed to lightning; and (2) The system automatically recovers...

  8. 14 CFR 27.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... after the time the rotorcraft is exposed to lightning; and (2) The system automatically recovers...

  9. 14 CFR 25.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... time the airplane is exposed to lightning; and (2) The system automatically recovers normal...

  10. 14 CFR 27.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... after the time the rotorcraft is exposed to lightning; and (2) The system automatically recovers...

  11. 14 CFR 25.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... time the airplane is exposed to lightning; and (2) The system automatically recovers normal...

  12. 14 CFR 27.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... after the time the rotorcraft is exposed to lightning; and (2) The system automatically recovers...

  13. 14 CFR 29.1316 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Electrical and electronic system lightning... Electrical and electronic system lightning protection. (a) Each electrical and electronic system that... after the time the rotorcraft is exposed to lightning; and (2) The system automatically recovers...

  14. Potential donor segregation to promote blood donation.

    PubMed

    Martín-Santana, Josefa D; Beerli-Palacio, Asunción

    2008-04-01

    This work is set in the field of social marketing and more specifically in the context of blood donation. Its principal objective focuses on segregating potential donors by using the inhibitors or barriers to a blood donation behaviour as criteria. Moreover, an analysis of the predisposition to donate blood, the intrinsic and extrinsic motivations for donating blood, and the incentives that may stimulate their donation conduct was conducted for each of the four identified groups. The results reveal that the four segments differ significantly in their predisposition to donate, in their motivations and in the incentives that encourage them to donate blood. PMID:18343199

  15. Topologically protected entanglement of electron-pair cyclotron motions

    NASA Astrophysics Data System (ADS)

    Champel, T.; Hernangómez-Pérez, D.; Florens, S.

    2016-02-01

    Considering two-dimensional electron gases under a perpendicular magnetic field, we pinpoint a specific kind of long-range bipartite entanglement of the electronic motions. This entanglement is achieved through the introduction of bicomplex spinorial eigenfunctions admitting a polar decomposition in terms of a real modulus and three real phases. Within this bicomplex geometry the cyclotron motions of two electrons are intrinsically tied, so that the highlighted eigenstates of the kinetic energy operator actually describe the free motion of a genuine electron pair. Most remarkably, these states embody phase singularities in the four-dimensional (4D) space, with singular points corresponding to the simultaneous undetermination of the three phases. Because the entanglement between the two electrons forming a pair, as well as the winding and parity quantum numbers characterizing the 4D phase singularity, are topological in nature, we expect them to manifest some robustness in the presence of a smooth disorder potential and an electron-electron interaction potential. The relevance of this effective approach in terms of 4D vortices of electron pairs is discussed in the context of the fractional quantum Hall effect.

  16. Gender disparity in organ donation.

    PubMed

    Steinman, Judith L

    2006-12-01

    Organ donation is affected by legal, cultural, religious, and racial factors, as well as by health considerations. Although organs in and of themselves are gender neutral and can be exchanged between the sexes, women account for up to two thirds of all organ donations. There are no clear reasons why women are more willing to undergo the risks of surgery than are men, nor is this gender disparity mirrored in the demand for donated organs. More men than women are recipients, and women are less likely to complete the necessary steps to receive donated organs. Internationally, ethical concern has been focused on possible human rights violations in the harvesting of organs from prisoners and, in poor countries, on the trafficking of organs from girls and women who are expected to financially help their families by selling their organs. PMID:17582366

  17. Brain death and organ donation.

    PubMed

    Lovasik, D

    2000-12-01

    Critical care nurses are essential team members during the process of determining brain death and preparing for organ donation. Using their knowledge of the criteria for brain death, they care for the dying patient, support the grieving family, and participate in the consent process for organ donation. Nurses make a critical difference in saving the lives of others through the gift of life. PMID:11855256

  18. Organ donation: a nursing perspective.

    PubMed

    Maher, M E; Strong, S

    1989-12-01

    The frequency and success rate of organ donation and transplant surgery has dramatically increased over the past several years. Since organ donors are drawn primarily from the traumatically brain-injured population this increase has a direct impact on neuroscience nurses. This article addresses the organ procurement process, nursing care of the organ donor and the interrelationship of organ donation and neuroscience nursing. PMID:2532669

  19. Complex Contagion of Campaign Donations.

    PubMed

    Traag, Vincent A

    2016-01-01

    Money is central in US politics, and most campaign contributions stem from a tiny, wealthy elite. Like other political acts, campaign donations are known to be socially contagious. We study how campaign donations diffuse through a network of more than 50000 elites and examine how connectivity among previous donors reinforces contagion. We find that the diffusion of donations is driven by independent reinforcement contagion: people are more likely to donate when exposed to donors from different social groups than when they are exposed to equally many donors from the same group. Counter-intuitively, being exposed to one side may increase donations to the other side. Although the effect is weak, simultaneous cross-cutting exposure makes donation somewhat less likely. Finally, the independence of donors in the beginning of a campaign predicts the amount of money that is raised throughout a campaign. We theorize that people infer population-wide estimates from their local observations, with elites assessing the viability of candidates, possibly opposing candidates in response to local support. Our findings suggest that theories of complex contagions need refinement and that political campaigns should target multiple communities. PMID:27077742

  20. Complex Contagion of Campaign Donations

    PubMed Central

    2016-01-01

    Money is central in US politics, and most campaign contributions stem from a tiny, wealthy elite. Like other political acts, campaign donations are known to be socially contagious. We study how campaign donations diffuse through a network of more than 50000 elites and examine how connectivity among previous donors reinforces contagion. We find that the diffusion of donations is driven by independent reinforcement contagion: people are more likely to donate when exposed to donors from different social groups than when they are exposed to equally many donors from the same group. Counter-intuitively, being exposed to one side may increase donations to the other side. Although the effect is weak, simultaneous cross-cutting exposure makes donation somewhat less likely. Finally, the independence of donors in the beginning of a campaign predicts the amount of money that is raised throughout a campaign. We theorize that people infer population-wide estimates from their local observations, with elites assessing the viability of candidates, possibly opposing candidates in response to local support. Our findings suggest that theories of complex contagions need refinement and that political campaigns should target multiple communities. PMID:27077742

  1. Overview of multimedia content protection in consumer electronics devices

    NASA Astrophysics Data System (ADS)

    Eskicioglu, Ahmet M.; Delp, Edward J., III

    2000-05-01

    A digital home network is a cluster of digital audio/visual (A/V) devices including set-top boxes, TVs, VCRs, DVD players, and general-purpose computing devices such as personal computers. The network may receive copyrighted digital multimedia content from a number of sources. This content may be broadcast via satellite or terrestrial systems, transmitted by cable operators, or made available as prepackaged media (e.g., a digital tape or a digital video disc). Before releasing their content for distribution, the content owners may require protection by specifying access conditions. Once the content is delivered to the consumer, it moves across home the network until it reaches its destination where it is stored or displayed. A copy protection system is needed to prevent unauthorized access to bit streams in transmission from one A/V device to another or while it is in storage on magnetic or optical media. Recently, two fundamental groups of technologies, encryption and watermarking, have been identified for protecting copyrighted digital multimedia content. This paper is an overview of the work done for protecting content owners' investment in intellectual property.

  2. Electronic Parts and Spacecraft Reliability : Considerations for Planetary Protection

    NASA Technical Reports Server (NTRS)

    Clark, Karla B.

    2011-01-01

    If considered from the beginning of design, its easier to incorporate approaches to meet planetary protection requirements Parts, materials and approaches are available to meet sterilization requirements. Cost impact is highly dependent on: (1) Level of PP requirements imposed, (2) Design (a) New or existing (b) Parts classification (c) Number of sensors (d) Calibration/alignment requirements

  3. Donation of eggs in assisted reproduction and informed consent.

    PubMed

    Uroz, Victoria; Guerra, Lucia

    2009-09-01

    In Spain, there exists an increasing amount of advertising for the donation of eggs for assisted reproduction. This study attempts to assess: (1) scientific evidence available about adverse effects of egg donation; (2) characteristics of the information given in the informed consent to donors; and (3) the legality of this advertising. The main results are: (1) Many severe problems are associated with induction of ovulation, as ovarian hyperstimulation (reported frequencies from 5.9 to 15%), thromboembolism, hepatic failure and increased risk of ovarian, breast, endometrial and colon cancer. (2) Informed consent for egg donors is very incomplete, according to the Spanish law 41/2002 on Patient's Information. (3) Current advertising to promote egg donation does not respect, among others, law 14/2006 about Assisted Human Reproduction, as it includes reference to economic compensation or benefits but no information about the risks. Deontological and judicial disciplinary procedures should be initiated to protect donors' rights. PMID:20157970

  4. Decreasing the energy consumption of memory devices by enhancing the conjugation extent of the terminal electron-donating moieties within molecules.

    PubMed

    Bo, Rongcheng; Liu, Hongzhang; Zhou, Qianhao; Chen, Dongyun; Xu, Qingfeng; Li, Najun; Li, Hua; Lu, Jianmei

    2015-02-01

    Three small organic molecules that contained a phenothiazine backbone and triphenylamine (TPA), carbazole (CZ), or anthracene (AN) as a terminal electron donor were synthesized and fabricated in ITO/organic film/Al sandwiched memory devices. The influence of the extent of conjugation in the three molecules on the performance of their corresponding devices was investigated and the results showed that all of the fabricated devices exhibited nonvolatile ternary WORM character, whilst the switch threshold voltages decreased on moving from TPA to CZ and AN, which is promising for low-power-consumption data storage. These results revealed that tailoring the extent of conjugation in the terminal electron donor in the D-A molecules could effectively optimize the device performance, in particular the switch-threshold voltage, which could be instructive for the design of low-energy-consumption memory materials. PMID:25403943

  5. An Electronic Rationale for Observed Initiation Rates in Ruthenium-Mediated Olefin Metathesis: Charge Donation in Phosphine And N-Heterocyclic Carbene Ligands

    SciTech Connect

    Getty, K.; Delgado-Jaime, M.U.; Kennepohl, P.

    2009-06-01

    Ru K-edge XAS data indicate that second generation ruthenium-based olefin metathesis precatalysts (L = N-heterocyclic carbene) possess a more electron-deficient metal center than in the corresponding first generation species (L = tricyclohexylphosphine). This surprising effect is also observed from DFT calculations and provides a simple rationale for the slow phosphine dissociation kinetics previously noted for second-generation metathesis precatalysts.

  6. Does the position of the electron-donating nitrogen atom in the ring system influence the efficiency of a dye-sensitized solar cell? A computational study.

    PubMed

    Biswas, Abul Kalam; Barik, Sunirmal; Das, Amitava; Ganguly, Bishwajit

    2016-06-01

    We have reported a number of new metal-free organic dyes (2-6) that have cyclic asymmetric benzotripyrrole derivatives as donor groups with peripheral nitrogen atoms in the ring, fluorine and thiophene groups as π-spacers, and a cyanoacrylic acid acceptor group. Density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations were employed to examine the influence of the position of the donor nitrogen atom and π-conjugation on solar cell performance. The calculated electron-injection driving force (ΔG inject), electron-regeneration driving force (ΔG regen), light-harvesting efficiency (LHE), dipole moment (μ normal), and number of electrons transferred (∆q) indicate that dyes 3, 4, and 6 have significantly higher efficiencies than reference dye 1, which exhibits high efficiency. We also extended our comparison to some other reported dyes, 7-9, which have a donor nitrogen atom in the middle of the ring system. The computed results suggest that dye 6 possesses a higher incident photon to current conversion efficiency (IPCE) than reported dyes 7-9. Thus, the use of donor groups with peripheral nitrogen atoms appears to lead to more efficient dyes than those in which the nitrogen atom is present in the middle of the donor ring system. Graphical Abstract The locations of the nitrogen atoms in the donor groups in the designed dye molecules have an important influence on DSSC efficiency. PMID:27155868

  7. On radiation protection at the LINAC-800 linear electron accelerator

    NASA Astrophysics Data System (ADS)

    Balalykin, N. I.; Minashkin, V. F.; Nozdrin, M. A.; Shirkov, G. D.; Schegolev, V. Yu.

    2012-07-01

    The Automatic System of Radiation Safety Control (ASRSC) of the LINAC-800 linear electron accelerator is designed to ensure radiation safety for accelerator personnel during regular operations and in emergency cases. The results of calculating the emission power used to develop the ARPS are given. Both hardware and software components of the radiation control system are described. This paper also presents a description of the interlock and signalization system.

  8. Improving kidney and live donation rates in Asia: living donation.

    PubMed

    Rizvi, S A H; Naqvi, S A A; Hashmi, A; Akhtar, F; Hussain, M; Ahmed, E; Zafar, M N; Abbas, Z; Jawad, F; Sultan, S; Hasan, S M

    2004-09-01

    Organ transplantation started with organs donated by living subjects. Increasing demands brought cadaveric organ donation. The brain-death law, mandatory for this procedure, is prevalent in all countries involved in organ transplantation except Pakistan. Spain is the leading country in cadaveric organ donation (32.5 pmp). Despite the sources of living and cadaveric organs, both heart-beating and non-heart-beating, the gap between the demand and supply has widened. An example is the United States, where the numbers of patients on the waiting list for kidney transplantation have risen from 30,000 in 1988 to more than 116,000 in 2001. This has caused a resurgence in living donors all over the world. These can be related, unrelated, spousal, marginal, or ABO-incompatible donors. Family apprehensions, medical care costs, and nonexistent social security can be barriers to this form of organ donation. Unrelated organ donation can open the doors to commercialism. To make this process more successful, transplantation should be made reachable by all sectors of the population. This is possible when transplantation is taken to the public sector institutions and financed jointly by the government and community. To increase living organ donation especially in Asian countries, which face barriers of low literacy rates, ignorance, and cultural and religious beliefs, more efforts are needed. Public awareness and education play an important role. Appreciation and supporting the donors is necessary and justified. It is a noble act and should be recognized by offering job security, health insurance, and free education for the donor's children. PMID:15518688

  9. Current Status of Organ Donation.

    PubMed

    Tuttle-Newhall, J E Betsy; Schnitzler, Mark

    2015-01-01

    Organ and tissue donation are options at the end of a patient's life. Physicians and surgeons should have no direct role to play in the solicitation of organ donation and consent for organ recovery from the family of either a brain dead patient or a neurologically devastated patient. Certainly organ and tissue donation, and transplant procedures are life-saving and life-changing for many patients with organ failure and life-altering conditions. Due in part to the disparity between supply and demand for these resources, the potential exists for ethical tensions between the caring physician and surgeon team's advocacy for their patient, and the family at the end of the patient's life, and the process of organ donation. In this article, we will discuss the evolution of the legislative landscape for organ donation in the past decade, the concept of first person consent and its implications, the process of recovery and finally concerns regarding issues of conflict of interest regarding the handling and processing of the donor gift. PMID:26168580

  10. [Blood donation in urban areas].

    PubMed

    Charpentier, F

    2013-05-01

    Medical and technical developments increase the difficulty to provide sufficient safe blood for all patients in developed countries and their sociodemographic and societal changes. Sufficient national blood supply remains a reached, however still actual, challenge. Tomorrow is prepared today: the management of blood donation programs both in line with these developments and with social marketing strategies is one of the keys to success. If the main components of this organization are well known (mobile blood drives in various appropriate environments, and permanent blood donation centers) their proportions in the whole process must evolve and their contents require adaptations, especially for whole blood donation in urban areas. We have to focus on the people's way of life changes related to increasing urbanization of the society and prominent position taken by very large cities. This requires targeting several goals: to draw the attention of the potential blood-giving candidate, to get into position to collect him when he will decide it, to give meaning and recognition to his "sacrifice" (give time rather than donate blood) and to give him desire and opportunity to come back and donate one more time. In this strategy, permanent blood centers in urban areas have significant potential for whole blood collection, highlighted by the decrease of apheresis technology requirements. This potential requires profound changes in their location, conception and organization. The concept of Maison Du Don (MDD) reflects these changes. PMID:23597586

  11. Donor Hemovigilance with Blood Donation

    PubMed Central

    Diekamp, Ulrich; Gneißl, Johannes; Rabe, Angela; Kießig, Stephan T.

    2015-01-01

    Background Reports on unexpected events (UEs) during blood donation (BD) inadequately consider the role of technical UEs. Methods Defined local and systemic UEs were graded by severity; technical UEs were not graded. On January 1, 2008, E.B.P.S.-Logistics (EBPS) installed the UE module for plasma management software (PMS). Donor room physicians entered UEs daily into PMS. Medical directors reviewed entries quarterly. EBPS compiled data on donors, donations, and UEs from January 1, 2008 to June 30, 2011. Results 6,605 UEs were observed during 166,650 BDs from 57,622 donors for a corrected incidence of 4.30% (0.66% local, 1.59% systemic, 2.04% technical UEs). 2.96% of BDs were accompanied by one UE and 0.45% by >1 UE (2-4). 6.3% of donors donating blood for their first time, 3.5% of those giving blood for their second time, and 1.9% of donors giving their third or more BD experienced UEs. Most common UEs were: discontinued collections due to venous access problems, repeated venipuncture, and small hematomas. Severe circulatory UEs occurred at a rate of 16 per 100,000 BDs. Conclusions Technical UEs were common during BD. UEs accompanied first and second donations significantly more often than subsequent donations. PMID:26195932

  12. 14 CFR 23.1306 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Electrical and electronic system lightning... Equipment General § 23.1306 Electrical and electronic system lightning protection. (a) Each electrical and... affected during and after the time the airplane is exposed to lightning; and (2) The system...

  13. 14 CFR 23.1306 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Electrical and electronic system lightning... Equipment General § 23.1306 Electrical and electronic system lightning protection. (a) Each electrical and... affected during and after the time the airplane is exposed to lightning; and (2) The system...

  14. 14 CFR 23.1306 - Electrical and electronic system lightning protection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Electrical and electronic system lightning... Equipment General § 23.1306 Electrical and electronic system lightning protection. (a) Each electrical and... affected during and after the time the airplane is exposed to lightning; and (2) The system...

  15. Organ Donation Campaigns: Perspective of Dialysis Patient's Family Members

    PubMed Central

    TUMIN, Makmor; RAJA ARIFFIN, Raja Noriza; MOHD SATAR, NurulHuda; NG, Kok-Peng; LIM, Soo-Kun; CHONG, Chin-Sieng

    2014-01-01

    Abstract Background Solving the dilemma of the organ shortage in Malaysia requires educating Malaysians about organ donation and transplantation. This paper aims at exploring the average Malaysian households ’ preferred channels of campaigns and the preferred campaigners in a family setting, targeting at the dialysis family members. Methods We analyzed the responses of 350 respondents regarding organ donation campaigns. The respondents are 2 family members of 175 dialysis patients from 3 different institutions. The information on respondents’ willingness to donate and preferred method and channel of organ donation campaign were collected through questionnaire. Results Malaysian families have a good tendency to welcome campaigns in both the public and private (their homes) spheres. We also found that campaigns facilitated by the electronic media (Television and Radio) and executed by experienced doctors are expected to optimize the outcomes of organ donation, in general. Chi-square tests show that there are no significant differences in welcoming campaigns among ethnics. However, ethnics preferences over the campaign methods and campaigners are significantly different (P <0.05). Conclusion Ethnic differences imply that necessary modifications on the campaign channels and campaigners should also be taken under consideration. By identifying the preferred channel and campaigners, this study hopes to shed some light on the ways to overcome the problem of organ shortage in Malaysia. PMID:25909060

  16. FAQ: Blood Donation and Organ Transplant

    MedlinePlus

    ... Mosquito Surveillance Software Health Education Public Service Videos Blood Donation & Organ Transplant Recommend on Facebook Tweet Share ... get infected with West Nile virus by donating blood? No. You cannot get West Nile virus by ...

  17. 48 CFR 245.609 - Donations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Donations. 245.609 Section 245.609 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF... Inventory 245.609 Donations. Agencies may donate, with GSA approval and without expense to the United...

  18. 17 CFR 256.426.1 - Donations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Donations. 256.426.1 Section... COMPANY ACT OF 1935 Income and Expense Accounts § 256.426.1 Donations. This account shall include all payments or donations for charitable, social or community welfare purposes....

  19. 31 CFR 596.301 - Donation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Donation. 596.301 Section 596.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN... Definitions § 596.301 Donation. The term donation means a transfer made in the form of a gift or...

  20. 31 CFR 596.301 - Donation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Donation. 596.301 Section 596.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN... Definitions § 596.301 Donation. The term donation means a transfer made in the form of a gift or...

  1. 31 CFR 596.301 - Donation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Donation. 596.301 Section 596.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN... Definitions § 596.301 Donation. The term donation means a transfer made in the form of a gift or...

  2. 31 CFR 596.301 - Donation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Donation. 596.301 Section 596.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN... Definitions § 596.301 Donation. The term donation means a transfer made in the form of a gift or...

  3. 31 CFR 596.301 - Donation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Donation. 596.301 Section 596.301 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN... Definitions § 596.301 Donation. The term donation means a transfer made in the form of a gift or...

  4. 17 CFR 256.426.1 - Donations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Donations. 256.426.1 Section... COMPANY ACT OF 1935 Income and Expense Accounts § 256.426.1 Donations. This account shall include all payments or donations for charitable, social or community welfare purposes....

  5. A Different Kind of Disaster Donation

    ERIC Educational Resources Information Center

    Johnson, Mary J.

    2006-01-01

    As one natural disaster after another seemed to define the year 2005, library workers across the nation generously donated money, materials, and labor to help victims and damaged institutions recover. Some librarians donated to specific institutions, while others donated to more general charities. Many worried about media reports of fraudulent…

  6. Organ Donation and Transplantation Statistics

    MedlinePlus

    ... KS KEEP Healthy Event at Charlotte Convention Center Sat, 07/23/2016 - 8:00am Charlotte, NC Patient ... Capital City 5K for Organ, Tissue & Eye Donation Sat, 07/30/2016 - 5:30pm Madison, WI Register ...

  7. 76 FR 33129 - Airworthiness Standards; Electrical and Electronic System Lightning Protection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... April 28, 1994 (59 FR 22112), specifically requiring protection for electrical and electronic systems on..., Notice No. 10-05, published in the Federal Register on April 2, 2010 (75 FR 16676), is the basis for this...--policies/or 3. Accessing the Government Printing Office's Web page at...

  8. Challenging the moral status of blood donation.

    PubMed

    Snelling, Paul C

    2014-12-01

    The World Health Organisation encourages that blood donation becomes voluntary and unremunerated, a system already operated in the UK. Drawing on public documents and videos, this paper argues that blood donation is regarded and presented as altruistic and supererogatory. In advertisements, donation is presented as something undertaken for the benefit of others, a matter attracting considerable gratitude from recipients and the collecting organisation. It is argued that regarding blood donation as an act of supererogation is wrongheaded, and an alternative account of blood donation as moral obligation is presented. Two arguments are offered in support of this position. First, the principle of beneficence, understood in a broad consequentialist framework obliges donation where the benefit to the recipient is large and the cost to the donor relatively small. This argument can be applied, with differing levels of normativity, to various acts of donation. Second, the wrongness of free riding requires individuals to contribute to collective systems from which they benefit. Alone and in combination these arguments present moral reasons for donation, recognised in communication strategies elsewhere. Research is required to evaluate the potential effects on donation of a campaign which presents blood donation as moral obligation, but of wider importance is the recognition that other-regarding considerations in relation to our own as well as others' health result in a range not only of choices but also of obligations. PMID:22983763

  9. On the opto-electronic properties of phosphine and thiolate-protected undecagold nanoclusters.

    PubMed

    Muniz-Miranda, Francesco; Menziani, Maria Cristina; Pedone, Alfonso

    2014-09-21

    We present here a detailed time-dependent density-functional theory investigation aimed at systematically dissecting the electronic spectra of two thiolate and phosphine protected undecagold nanoclusters. Calculations performed on the experimental structures of Au11(PPh3)7Cl3 and Au11(PPh3)7(SPyr)3 show that ligands have negligible contributions in the visible region. Metal → ligand charge transfer transitions appear at energies well above the visible threshold, while transitions with some small ligand → metal and ligand → ligand character occur sporadically at even higher energies. Thus, the conjugation effect between the π-electrons of the ligand and electrons of gold, recently hypothesized to interpret the spectra of phosphine and thiolate-protected nanoclusters, is not confirmed by the results of this study. PMID:25075579

  10. Oocyte donation: particular technical and ethical aspects.

    PubMed

    Englert, Y; Govaerts, I

    1998-05-01

    This paper analyses the reasons that oocyte and sperm donation are experienced very differently by couples, despite their apparent similarity, and stresses the impact of the difficulties on donor recruitment in all oocyte donation programmes. The various types of donors (occasional, relational, in-vitro fertilization patient and professional) are described together with their motivations, resistance, advantages and disadvantages. The contradictory consequences with free or paid donation, the particular risks of oocyte donation (in comparison with sperm donation) both for the donor and for the recipient are highlighted. The problem of maintaining anonymity is then analysed in ethical terms but also in terms of technical efficacy. A strategy is described which, due to the decision of retaining anonymity, authorizes the sharing of oocytes between recipients. This has as a consequence, an increase in treatment efficacy by avoiding wastage of oocytes offered as a donation. PMID:9665329

  11. Aspects of deceased organ donation in paediatrics.

    PubMed

    Brierley, J; Hasan, A

    2012-01-01

    Organ transplantation offers children in acute or chronic severe organ failure similar opportunities to adults. However, while the number who might benefit is relatively low, significantly fewer cadaveric donors exist for any given child compared with an adult. Incompatible organ size and relatively low donation rates mean that despite living parental donation and innovations to reduce donated organ size, children die before organs become available. The severity of the UK situation is compounded by restrictions on paediatric living donation, uncertainties over the application of brain death criteria, and ethical concerns about the use of donation after circulatory death. The UK Department of Health's Organ Donation Task Force suggested the means by which the adult donor pool might be increased, recommending that outstanding ethical and legal issues be resolved, but made no specific recommendations about children. PMID:22194438

  12. Ethical aspects of blood and organ donation.

    PubMed

    Whyte, G

    2003-08-01

    Ethics of blood and organ donation in Australia has been influenced by voluntarism and the Red Cross. The General Agreement on Trade in Services may threaten the principle of voluntary blood donation and self sufficiency of blood in Australia. However, a cooperative approach to managing the public good is more sustainable than individual self interest and the author argues that voluntary blood and organ donation should be retained. PMID:12895168

  13. Religious justifications for donating body parts.

    PubMed

    May, W F

    1985-02-01

    May discusses religious justifications for organ donation as alternatives to marketplace purchase, voluntary donation, and routine salvaging. He responds to Feinberg's proposal for a national system of salvaging and his criticism of the tendency to invest a dead body with symbolism that hampers organ donation. After exploring the implications for transplantation of the Christian Scientist, dualist, and Gnostic outlooks, May considers aspects of the Judeo-Christian tradition that influence attitudes toward organ donation and transplantation. He calls upon religious institutions to assume a leadership role in arousing conscience and in encouraging organized giving of organs. PMID:3980204

  14. Exploring Donation Decisions: Beliefs and Preferences for Organ Donation in Australia

    ERIC Educational Resources Information Center

    Hyde, Melissa K.; White, Katherine M.

    2010-01-01

    The authors explored common beliefs and preferences for posthumous and living organ donation in Australia where organ donation rates are low and little research exists. Content analysis of discussions revealed the advantage of prolonging/saving life whereas disadvantages differed according to donation context. A range of people/groups perceived to…

  15. [ELGA--the electronic health record in the light of data protection and data security].

    PubMed

    Ströher, Alexander; Honekamp, Wilfried

    2011-07-01

    The introduction of an electronic health record (ELGA) is a subject discussed for a long time in Austria. Another big step toward ELGA is made at the end of 2010 on the pilot project e-medication in three model regions; other projects should follow. In addition, projects of the ELGA structure are sped up on the part of the ELGA GmbH to install the base of a functioning electronic health record. Unfortunately, many of these initiatives take place, so to speak, secretly, so that in the consciousness of the general public - and that includes not only patients but also physicians and other healthcare providers - always concerns about protection and security of such a storage of health data arouse. In this article the bases of the planned act are discussed taking into account the data protection and data security. PMID:21858632

  16. Knowledge, attitude and practices of people towards voluntary blood donation in Uttarakhand

    PubMed Central

    Agrawal, Amit; Tiwari, Aseem K.; Ahuja, Alok; Kalra, Rakesh

    2013-01-01

    Introduction: Blood transfusions form a crucial and irreplaceable part in the medical management of many diseases. The collection of blood from voluntary, non-remunerated blood donors from low risk populations is an important measure for ensuring the availability and safety of blood transfusion. In a state like Uttarakhand which is visited by lakhs of visitors during pilgrimage season and where natural calamities and accidents are very common, the availability of blood is of utmost importance. Aim: To find out knowledge, attitude and practices of people towards voluntary blood donation to comprehend the situation and find ways to enhance voluntary blood donation in the state of Uttarakhand. Materials and Methods: Multi stage methodology was designed to target population including general population, influencers (doctors) and supporting organizations (camp organizers, State AIDS Control Society Officials) who were subjected to in-depth interview using pre-structured questionnaires to assess knowledge/awareness about voluntary blood donation, factors preventing and source of knowledge about voluntary blood donation. Result: The sample population consisted of mostly men (67%) in the age-group of 26-35 years. Requirement of blood and the measures to promote voluntary blood donation have a direct relationship with the total population and literacy level of the population. Awareness about blood donation, source of knowledge about blood donation, reasons for not donating blood are particularly stressed. With increase in educational level, the awareness level was also found to increase. While among illiterates 81 percent of the respondents knew about blood donation, among the post graduates the same ratio was found to be almost cent-percent. Among various reasons cited for not donating blood, lack of awareness being the most common reason. People gathered information about blood donation from several different sources with electronic media being the most prominent

  17. A Low-Dose Electron Diffraction Assay for Protection of Protein Structure against Damage from Drying

    NASA Astrophysics Data System (ADS)

    Massover, William H.

    2004-04-01

    A new assay using low-dose electron diffraction to measure the protection of protein structure against damage from drying is described. When thin single crystals of catalase are dried within water alone, low-dose electron diffraction yields no Bragg spots. Drying within an experimental aqueous solution that permits detection of diffraction spots thereby indicates a positive result, and the extent of these Bragg reflections into the high angle range gives a quantitative measure of the degree of protection. Bragg spots out to 3.7 3.9 [Angstrom capital A, ring] are recorded for drying within 100 mM solutions of the known structure-preserving sugars, sucrose, tannin, and trehalose. The ability of trehalose to maintain native protein structure during drying starts between 10 and 25 mM, and changes only slightly at concentrations above this threshold; with drying in 150-mM trehalose, catalase crystals yield diffraction spots out to 3.7 [Angstrom capital A, ring]. Drying within the organic nonsugar polymer polyvinylpyrrolidone gives Bragg spots to 4.0 [Angstrom capital A, ring]. This new assay should be useful to measure the unexamined structure-preserving capabilities of modified sugars, other nonsugars, and mixtures to identify which protective matrix maintains native protein structure to the greatest extent during drying; electron crystallography using that optimal matrix should yield protein structure at improved levels of high resolution.

  18. Audit Report on "Protection of the Department of Energy's Unclassified Sensitive Electronic Information"

    SciTech Connect

    2009-08-01

    The Department of Energy and its contractors store and process massive quantities of sensitive information to accomplish national security, energy, science, and environmental missions. Sensitive unclassified data, such as personally identifiable information (PII), official use only, and unclassified controlled nuclear information require special handling and protection to prevent misuse of the information for inappropriate purposes. Industry experts have reported that more than 203 million personal privacy records have been lost or stolen over the past three years, including information maintained by corporations, educational institutions, and Federal agencies. The loss of personal and other sensitive information can result in substantial financial harm, embarrassment, and inconvenience to individuals and organizations. Therefore, strong protective measures, including data encryption, help protect against the unauthorized disclosure of sensitive information. Prior reports involving the loss of sensitive information have highlighted weaknesses in the Department's ability to protect sensitive data. Our report on Security Over Personally Identifiable Information (DOE/IG-0771, July 2007) disclosed that the Department had not fully implemented all measures recommended by the Office of Management and Budget (OMB) and required by the National Institute of Standards and Technology (NIST) to protect PII, including failures to identify and encrypt PII maintained on information systems. Similarly, the Government Accountability Office recently reported that the Department had not yet installed encryption technology to protect sensitive data on the vast majority of laptop computers and handheld devices. Because of the potential for harm, we initiated this audit to determine whether the Department and its contractors adequately safeguarded sensitive electronic information. The Department had taken a number of steps to improve protection of PII. Our review, however, identified

  19. 49 CFR 24.108 - Donations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Donations. 24.108 Section 24.108 Transportation Office of the Secretary of Transportation UNIFORM RELOCATION ASSISTANCE AND REAL PROPERTY ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS Real Property Acquisition § 24.108 Donations. An owner whose...

  20. 49 CFR 24.108 - Donations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Donations. 24.108 Section 24.108 Transportation Office of the Secretary of Transportation UNIFORM RELOCATION ASSISTANCE AND REAL PROPERTY ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS Real Property Acquisition § 24.108 Donations. An owner whose...

  1. 49 CFR 24.108 - Donations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Donations. 24.108 Section 24.108 Transportation Office of the Secretary of Transportation UNIFORM RELOCATION ASSISTANCE AND REAL PROPERTY ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS Real Property Acquisition § 24.108 Donations. An owner whose...

  2. 49 CFR 24.108 - Donations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Donations. 24.108 Section 24.108 Transportation Office of the Secretary of Transportation UNIFORM RELOCATION ASSISTANCE AND REAL PROPERTY ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS Real Property Acquisition § 24.108 Donations. An owner whose...

  3. 49 CFR 24.108 - Donations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Donations. 24.108 Section 24.108 Transportation Office of the Secretary of Transportation UNIFORM RELOCATION ASSISTANCE AND REAL PROPERTY ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS Real Property Acquisition § 24.108 Donations. An owner whose...

  4. Understanding Australian families' organ donation decisions.

    PubMed

    Neate, S L; Marck, C H; Skinner, M; Dwyer, B; McGain, F; Weiland, T J; Hickey, B B; Jelinek, G A

    2015-01-01

    Numbers of deceased organ donors in Australia have increased, but rates of consent to donation remain at around 60%. Increasing family consent is a key target for the Australian Organ and Tissue Authority. Reasons for donation decisions have been reported in the international literature, but little is known of reasons for Australian families' decisions. Potential organ donors in four Melbourne hospitals were identified and 49 participants from 40 families (23 consenting and 17 non-consenting) were interviewed to understand reasons for consent decisions. Themes for consent to organ donation included that: donation was consistent with the deceased's explicit wishes or known values, the desire to help others or self-including themes of altruism, pragmatism, preventing others from being in the same position, consolation received from donation and aspects of the donation conversation and care that led families to believe donation was right for them. Themes for non-consent included: lack of knowledge of wishes; social, cultural and religious beliefs; factors related to the donation process and family exhaustion; and conversation factors where negative events influenced decisions. While reasons for consent were similar to those described in international literature, reasons for non-consent differed in that there was little emphasis on lack of trust of the medical profession, concerns regarding level of care provided to the potential donor, preserving the deceased's body, fears of body invasion or organ allocation fairness. PMID:25579288

  5. The Books in Bill Clinton's Donation.

    ERIC Educational Resources Information Center

    Zhang, Hongyang; Webb, T. D.

    2002-01-01

    Explains President Clinton's donation of books about the United States to the Peking University Library and compares it to a donation of Chinese books from the Peking University library to the library of Kapiolani Community College (Hawaii). Suggests appropriate directions for U.S.-China academic library cooperation and for international academic…

  6. Female College Students' Perceptions of Organ Donation

    ERIC Educational Resources Information Center

    Boland, Kathleen; Baker, Kerrie

    2010-01-01

    The current process of organ donation in the U.S. relies on the premise of altruism or voluntary consent. Yet, human organs available for donation and transplant do not meet current demands. The literature has suggested that college students, who represent a large group of potential healthy organ donors, often are not part of donor pools. Before…

  7. Giving Ourselves: The Ethics of Anatomical Donation

    ERIC Educational Resources Information Center

    Gunderman, Richard B.

    2008-01-01

    In some European countries, such as Italy, medical education is threatened by a dearth of anatomical specimens. Such a shortage could spread to other nations, including the United States. This article addresses two ethical questions in body donation. Why might people choose to donate their bodies to education and science? What sorts of ethical…

  8. [New conditions for organ donation in France].

    PubMed

    Antoine, Corinne; Maroudy, Daniel

    2016-09-01

    The procurement of organs from donors after circulatory death is a reliable technique which gives satisfactory posttransplant results and also represents a potential source of additional organs. In order to meet the growing need for organ donations, the 'anticipated organ donation approach' procedure is currently receiving renewed interest with new conditions for its implementation in France. PMID:27596496

  9. Altruism in organ donation: an unnecessary requirement?

    PubMed Central

    Moorlock, Greg; Ives, Jonathan; Draper, Heather

    2014-01-01

    Altruism has long been taken to be the guiding principle of ethical organ donation in the UK, and has been used as justification for rejecting or allowing certain types of donation. We argue that, despite this prominent role, altruism has been poorly defined in policy and position documents, and used confusingly and inconsistently. Looking at how the term has been used over recent years allows us to define ‘organ donation altruism’, and comparing this with accounts in the philosophical literature highlights its theoretical shortcomings. The recent report from the Nuffield Council on Bioethics reaffirmed the importance of altruism in organ donation, and offered a clearer definition. This definition is, however, more permissive than that of altruism previously seen in UK policy, and as a result allows some donations that previously have been considered unacceptable. We argue that while altruistic motivation may be desirable, it is not necessary. PMID:23538329

  10. Altruism in organ donation: an unnecessary requirement?

    PubMed

    Moorlock, Greg; Ives, Jonathan; Draper, Heather

    2014-02-01

    Altruism has long been taken to be the guiding principle of ethical organ donation in the UK, and has been used as justification for rejecting or allowing certain types of donation. We argue that, despite this prominent role, altruism has been poorly defined in policy and position documents, and used confusingly and inconsistently. Looking at how the term has been used over recent years allows us to define 'organ donation altruism', and comparing this with accounts in the philosophical literature highlights its theoretical shortcomings. The recent report from the Nuffield Council on Bioethics reaffirmed the importance of altruism in organ donation, and offered a clearer definition. This definition is, however, more permissive than that of altruism previously seen in UK policy, and as a result allows some donations that previously have been considered unacceptable. We argue that while altruistic motivation may be desirable, it is not necessary. PMID:23538329

  11. Crystal structure and electronic properties of a thiolate-protected Au24 nanocluster

    NASA Astrophysics Data System (ADS)

    Das, Anindita; Li, Tao; Li, Gao; Nobusada, Katsuyuki; Zeng, Chenjie; Rosi, Nathaniel L.; Jin, Rongchao

    2014-05-01

    Solving the total structures of gold nanoclusters is of critical importance for understanding their electronic, optical and catalytic properties. Herein, we report the X-ray structure of a charge-neutral Au24(SCH2Ph-tBu)20 nanocluster. This structure features a bi-tetrahedral Au8 kernel protected by four tetrameric staple-like motifs. Electronic structure analysis is further carried out and the optical absorption spectrum is interpreted. The Au24(SCH2Ph-tBu)20, Au23(S-c-C6H11)16 and Au25(SCH2CH2Ph)18 nanoclusters constitute the first crystallographically characterized ``trio''.Solving the total structures of gold nanoclusters is of critical importance for understanding their electronic, optical and catalytic properties. Herein, we report the X-ray structure of a charge-neutral Au24(SCH2Ph-tBu)20 nanocluster. This structure features a bi-tetrahedral Au8 kernel protected by four tetrameric staple-like motifs. Electronic structure analysis is further carried out and the optical absorption spectrum is interpreted. The Au24(SCH2Ph-tBu)20, Au23(S-c-C6H11)16 and Au25(SCH2CH2Ph)18 nanoclusters constitute the first crystallographically characterized ``trio''. Electronic supplementary information (ESI) available: Experimental and supporting Fig. S1-S3. CCDC NUMBER(1000102). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4nr01350f

  12. A randomised trial to demonstrate the effectiveness of electronic messages on sun protection behaviours.

    PubMed

    Szabó, Csanád; Ócsai, Henriette; Csabai, Márta; Kemény, Lajos

    2015-08-01

    Message exposure is effective at changing a variety of health behaviours. Our aim was to improve sun protection habits of a volunteer sample. We conducted a randomised, non-blinded, investigator-initiated trial (from 1st June to 31st August in 2011) on the effect of an electronic text-message system on sun protection behaviours. The assessments of 149 healthy volunteer participants took place at the Clinical Department of Dermatology and Allergology at the University of Szeged in Hungary. Psychological and medical assessments were also made. Total motivation scores for adherence to sunscreen use improved at a nearly significant level (t=-1.954, p=0.054). The intervention group used sunscreens more often than the other groups according to their sun exposure diaries (F=8.173, p<0.05) and their interview results (F=3.44, p<0.05). Using electronic messages offers an effective method to improve sun protection behaviours. Our intervention is a cost-effective method and it can easily be implemented at worksites. PMID:26114220

  13. [Structure, methodology and ethics of German commissions on living organ donation].

    PubMed

    Sievers, K; Neitzke, G

    2006-06-01

    Living organ donation is a medically established and morally acceptable method of transplantation. According to German Transplantation Law, an expert review by a local "Commission on Living Donation" (Lebendspendekommission, LSK) is required before transplantation. The legal task of this review is to ensure a voluntary decision by the donor and to rule out illegal trading of organs. Results from a national survey among all LSKs show that the process of review and assessment varies considerably among German LSKs. Most of them carry out a compulsory hearing of every potential donor, but this is omitted by some LSKs in a number of cases. Only 60% of all LSKs feel confident to determine donors' free will and protect their self-determination. Only 33% claim to be able to recognise illegal trading of organs. The LSKs even disagree on the exact borderline between legal incentives and illegal commerce. An expansion of living donation by financial incentives, pool-donation or crossover donation is supported only by a minority of German LSKs. The article argues in favour of establishing national standards for the process of LSK-reviews in order to foster procedural ethics and trustworthiness in the field of living organ donation. PMID:16755426

  14. Organ donation by capital prisoners in China: reflections in Confucian ethics.

    PubMed

    Wang, Mingxu; Wang, Xueliang

    2010-04-01

    This article discusses the practice and development of organ donation by capital prisoners in China. It analyzes the issue of informed consent regarding organ donation from capital prisoners in light of Confucian ethics and expounds the point that under the influence of Confucianism, China is a country that attaches great importance to the role of the family in practicing informed consent in various areas, the area of organ donation from capital prisoners included. It argues that a proper form of organ donation from capital prisoners can be justified within the Confucian moral context in which the proper interests of capital prisoners and their families, the benefit of organ receptors, and a rightful order of society should all be appropriately considered. From the Confucian perspective, the act of donating organs from a capital prisoner must be decided by both the prisoner and his/her family (i.e., each side should hold a veto power), whereas such donation, in the proper circumstance protected by a rightful procedure, should be appreciated as a morally praiseworthy act of the prisoner who is willing to make the final effort to repent and correct his/her evil conduct and to leave something good to the world. PMID:20197306

  15. How to increase living donation.

    PubMed

    Davis, Connie L

    2011-04-01

    Living donation is the key to increasing access to successful solid organ transplantation worldwide. However, the means to expanding the number of living donors on a global scale are not known. Although there have been many suggestions for the best approach, cultural issues may limit the effectiveness of some strategies. Only a few ideas have been studied, and one in particular- outright payment to donors - may raise ethical issues that are difficult to surmount and might negatively alter altruistic behavior. With respect to the present environment, this article will describe some of the approaches that are being discussed to increase the number of living donors, with a particular focus on kidney transplantation. PMID:21210867

  16. Electron Microscopy Abrasion Analysis of Candidate Fabrics for Planetary Space Suit Protective Overgarment Application

    NASA Technical Reports Server (NTRS)

    Hennessy, Mary J.

    1992-01-01

    The Electron Microscopy Abrasion Analysis of Candidate Fabrics for Planetary Space Suit Protective Overgarment Application is in support of the Abrasion Resistance Materials Screening Test. The fundamental assumption made for the SEM abrasion analysis was that woven fabrics to be used as the outermost layer of the protective overgarment in the design of the future, planetary space suits perform best when new. It is the goal of this study to determine which of the candidate fabrics was abraded the least in the tumble test. The sample that was abraded the least will be identified at the end of the report as the primary candidate fabric for further investigation. In addition, this analysis will determine if the abrasion seen by the laboratory tumbled samples is representative of actual EVA Apollo abrasion.

  17. The design and implementation of the machine protection system for the Fermilab electron cooling facility

    SciTech Connect

    Warner, A.; Carmichael, L.; Carlson, K.; Crisp, J.; Goodwin, R.; Prost, L.; Saewert, G.; Shemyakin, A.; /Fermilab

    2009-05-01

    The Fermilab Recycler ring employs an electron cooler to store and cool 8.9-GeV antiprotons. The cooler is based on a 4.3-MV, 0.1-A, DC electrostatic accelerator for which current losses have to remain low ({approx}10{sup -5}) in order to operate reliably. The Machine Protection System (MPS) has been designed to interrupt the beam in a matter of 1-2 {micro}s when losses higher than a safe limit are detected, either in the accelerator itself or in the beam lines. This paper highlights the various diagnostics, electronics and logic that the MPS relies upon to successfully ensure that no damage be sustained to the cooler or the Recycler ring.

  18. Electron flow through biological molecules: Does hole hopping protect proteins from oxidative damage?

    PubMed Central

    Winkler, Jay R.; Gray, Harry B.

    2016-01-01

    Biological electron transfers often occur between metal-containing cofactors that are separated by very large molecular distances. Employing photosensitizer-modified iron and copper proteins, we have shown that single-step electron tunneling can occur on nanosecond to microsecond timescales at distances between 15 and 20 angstroms. We also have shown that charge transport can occur over even longer distances by hole hopping (multistep tunneling) through intervening tyrosines and tryptophans. In this Perspective, we advance the hypothesis that such hole hopping through Tyr/Trp chains could protect oxygenase, dioxygenase, and peroxidase enzymes from oxidative damage. In support of this view, by examining the structures of P450 (CYP102A) and 2OG-Fe (TauD) enzymes, we have identified candidate Tyr/Trp chains that could transfer holes from uncoupled high-potential intermediates to reductants in contact with protein surface sites. PMID:26537399

  19. Oocyte donation programs: strategy for improving results.

    PubMed

    Borini, Andrea; Suriano, Rosanna; Barberi, Marzia; Dal Prato, Luca; Bulletti, Carlo

    2011-03-01

    Oocyte donation is now a useful option for women who cannot start a spontaneous pregnancy for reasons related to advanced age, iatrogenic factors, early depletion of ovarian reserve, or genetic disorders. Embryo implantation rates, pregnancy rates, and pregnancy outcomes among women included in oocyte donation programs were shown to be comparable to those of spontaneous or in vitro fertilization (IVF) pregnancies. With oocyte freezing and cryobanks, recipients may have a successful response to oocyte donation, with no need to be on waiting lists, access to a larger number of oocytes from the same donor, and a lesser risk of infectious disease transmission. PMID:21401626

  20. 45 CFR 2544.115 - Who may offer a donation?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Who may offer a donation? 2544.115 Section 2544... COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.115 Who may offer a donation? Anyone... donation to the Corporation....

  1. 41 CFR 109-44.702 - Donations to public bodies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Donations to public... AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.702 Donations to public bodies....

  2. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct...

  3. 39 CFR 777.51 - Acceptance of donations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Acceptance of donations. 777.51 Section 777.51... ACQUISITION POLICIES Donations § 777.51 Acceptance of donations. Nothing in these regulations shall prevent a person from making a gift or donation of real property or any part thereof, or any interest therein,...

  4. 41 CFR 109-44.702 - Donations to public bodies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Donations to public... AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.702 Donations to public bodies....

  5. 39 CFR 777.51 - Acceptance of donations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Acceptance of donations. 777.51 Section 777.51... ACQUISITION POLICIES Donations § 777.51 Acceptance of donations. Nothing in these regulations shall prevent a person from making a gift or donation of real property or any part thereof, or any interest therein,...

  6. 41 CFR 109-44.702 - Donations to public bodies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Donations to public... AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.702 Donations to public bodies....

  7. 45 CFR 2544.115 - Who may offer a donation?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Who may offer a donation? 2544.115 Section 2544... COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.115 Who may offer a donation? Anyone... donation to the Corporation....

  8. 2 CFR 200.434 - Contributions and donations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Contributions and donations. 200.434 Section... Cost § 200.434 Contributions and donations. (a) Costs of contributions and donations, including cash... space is not reimbursable either as a direct or indirect cost. (2) The value of the donations may...

  9. 45 CFR 2544.115 - Who may offer a donation?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Who may offer a donation? 2544.115 Section 2544... COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.115 Who may offer a donation? Anyone... donation to the Corporation....

  10. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct...

  11. 45 CFR 2544.115 - Who may offer a donation?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Who may offer a donation? 2544.115 Section 2544... COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.115 Who may offer a donation? Anyone... donation to the Corporation....

  12. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct...

  13. 45 CFR 2544.115 - Who may offer a donation?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Who may offer a donation? 2544.115 Section 2544... COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.115 Who may offer a donation? Anyone... donation to the Corporation....

  14. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct...

  15. 42 CFR 433.54 - Bona fide donations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Bona fide donations. 433.54 Section 433.54 Public... Financial Participation § 433.54 Bona fide donations. (a) A bona fide donation means a provider-related donation, as defined in § 433.52, made to the State or unit of local government, that has no direct...

  16. 39 CFR 777.51 - Acceptance of donations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Acceptance of donations. 777.51 Section 777.51... ACQUISITION POLICIES Donations § 777.51 Acceptance of donations. Nothing in these regulations shall prevent a person from making a gift or donation of real property or any part thereof, or any interest therein,...

  17. Knowledge Regarding Organ Donation and Willingness to Donate among Health Workers in South-West Nigeria

    PubMed Central

    Oluyombo, R.; Fawale, M. B.; Ojewola, R. W.; Busari, O. A.; Ogunmola, O. J.; Olanrewaju, T. O.; Akinleye, C. A.; Oladosu, Y. O.; Olamoyegun, M. A.; Gbadegesin, B. A.; Obajolowo, O. O.; Soje, M. O.; Adelaja, A.; Ayodele, L. M.; Ayodele, O. E.

    2016-01-01

    Background: Organ transplantation program in developing countries is still significantly dwarfed. Health workers are undeniably important in the success of transplantation. Objective: To assess the knowledge and attitude of health workers toward organ donation in South-West Nigeria with a view to explaining reasons for these shortcomings. Methods: In a cross-sectional study conducted on 850 health care workers, self-administered questionnaires were used to obtain information from participants. Results: Of 850 participants, 766 (90.1%) returned their completed questionnaires. The mean±SD age of participants was 36.7±9.2 years. Majority (93.3%) of participants had heard of organ donation; 82.5% had desirable knowledge. Only 29.5% and 39.4% would be willing to donate and counsel potential organ donors, respectively; 36.5% would consider signing organ donation cards. Only 19.4% believed that organ transplantation is often effective and 63.4% believed they were permitted by their religion to donate. Permission by religion (OR 3.5; 95% CI 2.3 to 5.3), good knowledge (OR 2.9; 95% CI 1.4 to 5.7), readiness to sign donation cards (OR 2.6; 95% CI 1.7 to 3.8), discuss organ donation (OR 2.7; 95%CI 8.0 to 63.8), and knowing somebody who had donated (OR 2.9) independently influenced willingness to donate organ. Conclusion: There is disparity in knowledge of organ donation and willingness to donate among health care workers. Efforts should be intensified to give comprehensive and appropriate education to health care workers about organ donation to bridge this gap. PMID:26889370

  18. Public Opinion on Organ Donation After Death and Its Influence on Attitudes Toward Organ Donation.

    PubMed

    Aijing, Luo; Wenzhao, Xie; Wei, Wei; Qiquan, Wan; Xuantong, Deng

    2016-01-01

    BACKGROUND China officially launched a pilot program of organ donation after cardiac death to overcome the shortage of available organs since 2011. Voluntary organ donation by deceased citizens became the only source of transplant organs beginning January 1, 2015. To investigate public opinions on organ donation by deceased donors, and discuss the effect of these opinions on the willingness and attitude of the public regarding voluntary organ donation. MATERIAL AND METHODS We designed a questionnaire. The survey was conducted from December 2014 to January 2015 in Changsha City, and 417 valid questionnaires were recovered. RESULTS A total of 162 respondents explicitly expressed a willingness to donate organs, and 269 believed that the organ donors' relatives should be compensated. A total of 255 respondents thought it acceptable to complete the donation-consent form when receiving a driver's license. Among the respondents, 65.3% did not agree with the statement "My body is bestowed by my parents, and to donate my body parts would not display filial respect"; 88.9% agreed that "It is necessary to consider the willingness of my family"; 74.4% agreed that "Donated organs have not been fairly and appropriately used; the wealthy and celebrities have been favored"; and 61.4% agreed that "Organ donation laws and regulations are not well developed, and organ donations will result in unnecessary difficulties." More than 80% believed that organ donation and transplantation extend life. CONCLUSIONS Public opinions on organ donation after death are associated with various factors, including traditional values, religious beliefs, compensation mechanisms, donor registration, institutional credibility, and ideals. PMID:27535587

  19. To donate or not donate, that is the question: an analysis of the critical factors of blood donation.

    PubMed

    Pereira, Jefferson Rodrigues; Sousa, Caissa Veloso E; Matos, Eliane Bragança de; Rezende, Leonardo Benedito Oliveira; Bueno, Natália Xavier; Dias, Álvaro Machado

    2016-08-01

    Currently, in Brazil, 1.78% of the population area blood donors, a level lower than the ideal one that, according to WHO, should be between 3% and 5% of the population. Following this scenario, the current study has a general goal of identifying and analyzing the main critical factors of the process of blood donation in the city of Belo Horizonte, MG, under the perception of donors, potential donors and non donors. A qualitative research approach was conducted, through twenty-four semi-structured interviews. The results highlight the lack of information in the various stages of the blood donation system. During the stages of donor recruitment and awareness, communication actions convey to society incomplete information about the donation process, discouraging future actions of donation. On the other hand, a lack of appreciation of the donation experience and the construction of social values associated with the donor prevent the multiplication of social behaviors for donation. The results of this study, found from theoretical framework outlined in this study, highlight the causes or critical factors that impede changes in behavior, incremental or radical, proposed by social marketing. PMID:27557020

  20. Genes and gestation in Australian regulation of egg donation, surrogacy and mitochondrial donation.

    PubMed

    Ludlow, Karinne

    2015-12-01

    This article considers genetic and legal relatedness for the purposes of Australian regulation of egg donation, surrogacy and parentage by examination of that regulation through the lens of mitochondrial (mt) donation. The article addresses whether mt donors would be a child's genetic parents following clinical use in that child's conception should mt donation be legalised for such use in Australia. It then considers how genetic and gestational relatedness are relevant in the discourse around legal parentage following egg donation and surrogacy and argues that the current approach is in need of reform so that intending parents of all children are deemed to be the resulting child's legal parents at birth. PMID:26939505

  1. Conflicting attitudes to corneal and organ donation: a study of nurses' attitudes to organ donation.

    PubMed

    Kent, B; Owens, R G

    1995-10-01

    The demand for transplantable organs and tissues is steadily increasing and action is necessary to improve the organ and tissue donation rates. Previous research has suggested that nurses have a substantial influence on the rates of donation in the clinical area. Nurses (N = 150) were asked to complete a number of measures to assess positive and negative attitudes towards cadaveric organ donation, with 112 (74.6%) responding. The findings identified conflicting attitudes particularly in relation to corneal donation; 25% of the respondents would not donate their corneas. Reasons given included fear of disfigurement, religious factors such as the need to see into the next life, and dislike of the thought of donation of eyes but without knowing why. The majority of the respondents were in favour of donation generally and many carried or had signed donor cards. Nurses are usually the professionals who have the most contact with the patient in the clinical and are therefore able to identify potential donors. It seems likely that nurses with conflicting attitudes to donation are less likely to undertake the emotional costs involved when relatives of potential donors are approached re donation, than those who have more positive attitudes. PMID:8550308

  2. The challenges of social marketing of organ donation: news and entertainment coverage of donation and transplantation.

    PubMed

    Harrison, Tyler R; Morgan, Susan E; Chewning, Lisa V

    2008-01-01

    While great strides have been made in persuading the public to become potential organ donors, actual behavior has not yet caught up with the nearly universally favorable attitudes the public expresses toward donation. This paper explores the issue by situating the social marketing of organ donation against a broader backdrop of entertainment and news media coverage of organ donation. Organ donation storylines are featured on broadcast television in medical and legal dramas, soap operas, and other television serials approximately four times per month (not including most cable networks), and feature storylines that promote myths and fears of the organ donation process. National news and other non-fictionalized coverage of organ donation are even more common, with stories appearing over twenty times a month on average. These stories tend to be one-dimensional and highly sensationalized in their coverage. The marketing of organ donation for entertainment essentially creates a counter-campaign to organ donation, with greater resources and reach than social marketers have access to. Understanding the broader environmental context of organ donation messages highlights the issues faced by social marketing campaigns in persuading the public to become potential donors. PMID:18935879

  3. Blood Donation and Transfusion (Beyond the Basics)

    MedlinePlus

    ... Examples of such infections are Ebola virus and Zika virus. The pre-donation educational material given to donors, ... infections are more common (eg, possible exposure to Zika virus due to travel to certain countries). In addition, ...

  4. Blood donation on posters: a worldwide review.

    PubMed

    Lefrère, Jean-Jacques; Danic, Bruno

    2012-06-01

    Originally pasted on walls and on locations reserved specially for that purpose, the poster is a medium for advertising and promotion to be seen on the streets and in public places. More recently, it has spread, in a smaller format, on dedicated indoor sites: billboards, columns, street furniture, and so forth. For transfusion, it appeared early on that the poster constitutes an important medium to promote blood donation. Thousands of posters supporting regional, national, or international blood donation campaigns have been created all over the planet, with a great variability of images, symbols, and slogans, which are particularly revealing about the image and the reality of blood donation. The topic is rich in information, particularly sociologic, on the variety of ways in which transfusion organizations promote blood donation. The authors present in this article the results of a study based on a total of 283 posters from nations on every continent, divided into 24 different themes. PMID:22070660

  5. [Organs, tissues, and cells donation in Mexico].

    PubMed

    Moreno-Treviño, María Guadalupe; Rivera-Silva, Gerardo

    2015-01-01

    Transplants are one of the most important advances of modern medicine; in the last 50 years in our country there have been more than fifty thousand transplants, which makes it clear that this is one of the most sought-after medical practices not only in Mexico but worldwide. In life, it is possible for a person to donate a kidney, a lung or a liver segment. When brain death occurs it is possible for a person to donate kidneys, heart, liver, pancreas, intestines, lungs, blood, hematopoietic cells, bone marrow, bones, corneas, heart valves, tendons, and arteries. However, the culture of organ donation is not widespread among Mexicans, hence in our country there is not even 50 % of the number of donations recommended by WHO, which impacts the number of patients who are waiting for an organ or tissue, which causes many of them die before receiving them. PMID:26506496

  6. [Cultural diversity in gamete and embryos donation].

    PubMed

    Epelboin, S

    2014-09-01

    Through gamete and embryo donation have successively emerged new ways of designing individuals who, in turn, have generated mutations in the concept of parenthood. A debate is open to the society, which often raises ideological cleavages. Indeed, donation practices mobilize the conflicting interests of donor of gametes, the recipient couple, child, whose origins are complex, although his filiation is legally clear. Its place in the family genealogy can be examined in relation to other societies, which admit plural concepts called "classificatory" kinship. They set up role partition between parents and educators. Setting anthropological perspective provides a broadening of the reflection to answer questions from the donation practices, including genealogical questions of revelation to the child of his conception, his incorporation in family and social group and the importance of compensation of donation. PMID:25153433

  7. Paid Organ Donation: An Italian Perspective.

    PubMed

    Bruzzone, P

    2015-09-01

    The only countries that have allowed financial incentives for organ donation are Iran since 1988, and later on, Singapore and Saudi Arabia. In Europe, and of course in Italy, financial incentives for donors are prohibited. The author has completed extensive research via the Internet (PubMed) of worldwide scientific literature on paid organ donation, also researching studies concerning public opinion on organ commercialism and "regulated markets". Italian transplant laws also have been reported and analyzed. PMID:26361655

  8. Brain death and organ donation of children.

    PubMed

    Gündüz, Ramiz Coşkun; Şahin, Şanlıay; Uysal-Yazıcı, Mutlu; Ayar, Ganime; Yakut, Halil İbrahim; Akman, Alkım Öden; Hirfanoğlu, İbrahim Murat; Kalkan, Gökhan

    2014-01-01

    We aimed to define the demographic characteristics, clinical features and outcome of patients with brain death, and to emphasize the importance of organ donation from children. Data for the period from September 2009 to October 2012 were collected retrospectively. Twenty children who were diagnosed as brain death were included. Data including demographics, major cause leading to brain death, duration of brain death evaluation, ancillary tests used to confirm brain death, complications and outcome, duration of hospitalization and organ donation were collected for statistical evaluation. The mean age was 6.2 years, and the male/female ratio 1.85. The major cause leading to brain death was most often traumatic brain injury, seen in 11 patients (55%). The mean duration of brain death evaluation was 6.7 and 1.7 days in Centers I and II respectively. The mean duration of hospitalization was 12.5 days. Electroencephalography (EEG) was used in 18 patients (90%). Complications included hyperglycemia in 13 cases and diabetes incipitus in 7 cases (65% and 35%, respectively). Mean duration of survival was 9.8 days. In Center I, one of the patients' parents gave consent to organ donation, while four parents in Center II agreed to organ donation. The study demonstrated that the duration of brain death evaluation was longer in Center I than in Center II (p<0.05). When both centers were compared, there was no significant difference in regard to obtaining consent for organ donation, survival after diagnosis of brain death and length of stay in the PICU (p>0.05). Early diagnosis of brain death and prompt evaluation of patients by ICU physicians once the diagnosis is taken into consideration will probably yield better organs and reduce costs. Training PICU physicians, nurses and organ donation coordinators, and increasing children's awareness of the need for organ donation via means of public communication may increase families' rate of agreement to organ donation in the future. PMID

  9. 78 FR 57539 - Charitable Donation Accounts

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ... contributions and donations is among an FCU's incidental powers.\\2\\ \\1\\ 12 U.S.C. 1757(17). \\2\\ 44 FR 56691 (Oct. 2, 1979); 64 FR 19441 (Apr. 21, 1999); 12 CFR 721.3. Between 1999 and 2012, FCU donations were... create charitable foundations. \\3\\ 12 CFR 701.25(a) (2011). \\4\\ Id. 12 CFR 701.25(b). \\5\\ 77 FR...

  10. Campaigning for Organ Donation at Mosques.

    PubMed

    Rady, Mohamed Y; Verheijde, Joseph L

    2016-09-01

    There is a trend of recruiting faith leaders at mosques to overcome religious barriers to organ donation, and to increase donor registration among Muslims. Commentators have suggested that Muslims are not given enough information about organ donation in religious sermons or lectures delivered at mosques. Corrective actions have been recommended, such as funding campaigns to promote organ donation, and increasing the availability of organ donation information at mosques. These actions are recommended despite published literature expressing safety concerns (i.e., do no harm) in living and end-of-life organ donation. Living donors require life-long medical follow-up and treatment for complications that can appear years later. Scientific and medical controversies persist regarding the international guidelines for death determination in end-of-life donation. The medical criteria of death lack validation and can harm donors if surgical procurement is performed without general anesthesia and before biological death. In the moral code of Islam, the prevention of harm holds precedence over beneficence. Moral precepts described in the Quran encourage Muslims to be beneficent, but also to seek knowledge prior to making practical decisions. However, the Quran also contains passages that demand honesty and truthfulness when providing information to those who are seeking knowledge. Currently, information is limited to that which encourages donor registration. Campaigning for organ donation to congregations in mosques should adhere to the moral code of complete, rather than selective, disclosure of information. We recommend as a minimal standard the disclosure of risks, uncertainties, and controversies associated with the organ donation process. PMID:26940813

  11. Free blood donation mobile applications.

    PubMed

    Ouhbi, Sofia; Fernández-Alemán, José Luis; Toval, Ambrosio; Idri, Ali; Pozo, José Rivera

    2015-05-01

    Blood donation (BD) is a noble act and mobile applications (apps) can help increase awareness about it. This paper analyzes and assesses the characteristics of free apps for BD as regards features and functionality. A search in Google Play, Apple Apps store, Blackberry App World and Windows Mobile App store was carried out to select 169 free BD apps from the 188 apps identified. The results presented in this paper show that the majority of the apps selected have been developed for the Android operating system. Moreover, most of the apps selected are available to help users search for donors. Few of the apps could not be installed and/or accessed. Of those that could be installed: half of them do not require any kind of authentication; a few of them are available in more than one language; half of them have a geographical restriction; around 60 % of them do not notify the user of BD events and requests; one, which is available for Android and iOS, can connect with a laboratory; around 45 % of them allow users to share information via social networks, and the majority of them do not provide BD recommendations. These results are used as a basis to provide app developers with certain recommendations. There is a need for better BD apps with more features in order to increase the number of volunteer donors. PMID:25732077

  12. Integrating a Machine Protection System for High-Current Free Electron Lasers and Energy Recovery Linacs

    SciTech Connect

    Trent Allison; James Coleman; Richard Evans; Al Grippo; Kevin Jordan

    2002-09-01

    A fully integrated Machine Protection System (MPS) is critical to efficient commissioning and safe operation of all high-current accelerators. The MPS needs to monitor the status of all devices that could enter the beam path, the beam loss monitors (BLMs), magnet settings, beam dump status, etc. This information is then presented to the electron source controller, which must limit the beam power or shut down the beam completely. The MPS for the energy recovery linac (ERL) at the Jefferson Lab Free Electron Laser [1] generates eight different power limits, or beam modes, which are passed to the drive laser pulse controller (DLPC) (photocathode source controller). These range from no beam to nearly 2 megawatts of electron beam power. Automatic masking is used for the BLMs during low-power modes when one might be using beam viewers. The system also reviews the setup for the two different beamlines, the IR path or the UV path, and will allow or disallow operations based on magnet settings and valve positions. This paper will describe the approach taken for the JLab 10-kW FEL. Additional details can be found on our website http://laser.jlab.org [2].

  13. The Mectizan Donation Program (MDP).

    PubMed

    Thylefors, B

    2008-09-01

    The launch of the Mectizan Donation Program (MDP) in 1987, by Merck & Co., Inc., created a number of new opportunities for onchocerciasis control. The microfilaricide Mectizan was rapidly put to ?use by the Onchocerciasis Control Programme in West Africa (OCP), for mass treatment by field teams in selected areas. Other milestones in Mectizan treatment included the establishment, in 1992, of the Onchocerciasis Elimination Program for the Americas, and the creation of the African Programme for Onchocerciasis Control (APOC) in 1995, the latter programme covering all African countries in need outside of the OCP area. In 1998, the donation of Mectizan was expanded to include the treatment of lymphatic filariasis in those African countries where that disease is co-endemic with onchocerciasis. In the past, the development of a broad partnership around the MDP played a very important role, including non-governmental development organizations collaborating with the ministries of health in endemic countries. A new community-directed treatment strategy, which made it easier to reach out to all those in need, including those in remote areas, was developed by the APOC in collaboration with the World Health Organization's Special Programme for Research and Training in Tropical Diseases (TDR). Several drug-management issues, including dosing, shelf-life, safety, and the reporting of severe adverse experiences, were addressed by the MDP, through its Mectizan Expert Committee, and by Merck & Co., Inc. A major research effort for the safe treatment of onchocerciasis in loiasis-endemic areas has also been supported by the MDP. Presently there are national programmes for Mectizan mass treatment in all 33 endemic countries in need of such treatment; >69 million Mectizan treatments for onchocerciasis were provided during 2006, and this number is expected to grow to at least 100 million treatments/year by 2010. This achievement has resulted in great public-health and socio

  14. EULID project: European living donation and public health.

    PubMed

    Manyalich, M; Ricart, A; Martínez, I; Balleste, C; Paredes, D; Vilardell, J; Avsec, D; Dias, L; Fehrman-Eckholm, I; Hiesse, C; Kyriakides, G; Line, P D; Maxwell, A; Nanni Costa, A; Paez, G; Turcu, R; Walaszewski, J

    2009-01-01

    The choice of transplantation from a living donor offers advantages over a deceased donor. However, it also carries disadvantages related to donor risks in terms of health and safety. Furthermore, there are several controversial ethical aspects to be taken into account. Several national and international institutions and the scientific community have stated standards that have great influence on professional codes and legislations. Living organ donation and transplantation are to some extent regulated by parliamentary acts in most European countries. It is necessary to take a step forward to develop a legal framework to regulate all of these processes to guarantee the quality and to prevent illegal and nonethical practices. It is also necessary to develop and implement living donor protection practices not only in terms of physical health, but also to minimize potential impacts on the psychological, social, and economic spheres. Finally, an additional effort should be made to create a database model with recommendations for registration practices as part of the standardized follow-up care for the living donor. The European Living Donation (EULID) project's (http://www.eulivingdonor.eu/) main objective was to contribute to a European consensus to set standards and recommendations about legal, ethical, and living donor protection practices to guarantee the health and safety of living donors. PMID:19715823

  15. Organ donation consanguinity or universality.

    PubMed

    Kishore, R R

    1996-01-01

    1. Neither the "Diseased Persons" nor the "Genetic Relations" provide an answer to "trading" in human body parts. 2. Live human body constitutes a vital source of supply of organs and tissues and the possibilities of optimum utilisation should be explored. 3. There is no scope for dogmatic postures and open-mindedness should be the approach while dealing with the issue of Organ Transplantation. 4. Society owes a duty to save the file of a dying man and in the event of failure to do so, it is absolutely immoral to interfere with his own arrangements by making unrealistic laws. No immorality is involved if an individual disposes of his spare body parts for a valid consideration to a needy person. 5. The scarcity needs to be urgently overcome otherwise unwarranted trade and crime are liable to thrive. 6. Families are not unconnected or antagonistic fragments of humanity. After thousands of years of continuous efforts the individuals on this earth have attained the stage of organic and functional integration. Atomisation of society on the basis of consanguineous proximities amounts to reversing this holistic trend. Organ transplantation is a functional expression of a highly evolved pursuit with inherent and intimate interaction in the form of organic exchange at the individual level, independent of consanguineous inducements or motivations. As such there is absolutely no scope for restricting organ donations by strangers. 7. Commercialisation should be curbed by making the enforcement agencies more efficient and not by depriving a needy person of his genuine requirements. Legislative craftsmanship lies in providing an answer without curtailing the freedom of the people. PMID:8692005

  16. Synthesis, anti-inflammatory activity and ulcerogenic liability of novel nitric oxide donating/chalcone hybrids.

    PubMed

    Abuo-Rahma, Gamal El-Din A A; Abdel-Aziz, Mohamed; Mourad, Mai A E; Farag, Hassan H

    2012-01-01

    A group of novel nitric oxide (NO) donating chalcone derivatives was prepared by binding various amino chalcones with different NO donating moieties including; nitrate ester, oximes and furoxans. Most of the prepared compounds showed significant anti-inflammatory activity using carrageenan-induced rat paw edema method compared with indomethacin. The prepared compounds exhibited more protection than indomethacin in regard to gastric toxicity. Histopathological investigation confirmed the beneficial effects of the NO releasing compounds in reducing ulcer formation. The incorporation of the NO-donating group into the parent chalcone derivatives caused a moderate increase in the anti-inflammatory activity with a marked decrease in gastric ulcerations compared to their parent chalcone derivatives. PMID:22137931

  17. Worldwide variability in deceased organ donation registries

    PubMed Central

    Rosenblum, Amanda M; Li, Alvin Ho-Ting; Roels, Leo; Stewart, Bryan; Prakash, Versha; Beitel, Janice; Young, Kimberly; Shemie, Sam; Nickerson, Peter; Garg, Amit X

    2012-01-01

    The variability in deceased organ donation registries worldwide has received little attention. We considered all operating registries, where individual wishes about organ donation were recorded in a computerized database. We included registries which recorded an individual's decision to be a donor (donor registry), and registries which only recorded an individual's objection (non-donor registry). We collected information on 15 characteristics including history, design, use and number of registrants for 27 registries (68%). Most registries are nationally operated and government-owned. Registrations in five nations expire and require renewal. Some registries provide the option to make specific organ selections in the donation decision. Just over half of donor registries provide legally binding authorization to donation. In all national donor registries, except one, the proportion of adults (15+) registered is modest (<40%). These proportions can be even lower when only affirmative decisions are considered. One nation provides priority status on the transplant waiting list as an incentive to affirmative registration, while another nation makes registering a donation decision mandatory to obtain a driver's license. Registered objections in non-donor registries are rare (<0.5%). The variation in organ donor registries worldwide necessitates public discourse and quality improvement initiatives, to identify and support leading practices in registry use. PMID:22507140

  18. Legal briefing: organ donation and allocation.

    PubMed

    Pope, Thaddeus Mason

    2010-01-01

    This issue's "Legal Briefing" column covers legal developments pertaining to organ donation and allocation. This topic has been the subject of recent articles in JCE. Organ donation and allocation have also recently been the subjects of significant public policy attention. In the past several months, legislatures and regulatory agencies across the United States and across the world have changed, or considered changing, the methods for procuring and distributing human organs for transplantation. Currently, in the U.S., more than 100,000 persons are waiting for organ transplantation. In China, more than 1.5 million people are waiting. Given the chronic shortage of available organs (especially kidneys and livers) relative to demand, the primary focus of most legal developments has been on increasing the rate of donation. These and related developments are usefully divided into the following 12 topical categories: 1. Revised Uniform Anatomical Gift Act. 2. Presumed Consent and Opt-Out. 3. Mandated Choice. 4. Donation after Cardiac Death. 5. Payment and Compensation. 6. Donation by Prisoners. 7. Donor Registries. 8. Public Education. 9. Other Procurement Initiatives. 10. Lawsuits and Liability. 11. Trafficking and Tourism. 12. Allocation and Distribution. PMID:21089996

  19. Living kidney donation: outcomes, ethics, and uncertainty.

    PubMed

    Reese, Peter P; Boudville, Neil; Garg, Amit X

    2015-05-16

    Since the first living-donor kidney transplantation in 1954, more than half a million living kidney donations have occurred and research has advanced knowledge about long-term donor outcomes. Donors in developed countries have a similar life expectancy and quality of life as healthy non-donors. Living kidney donation is associated with an increased risk of end-stage renal disease, although this outcome is uncommon (<0·5% increase in incidence at 15 years). Kidney donation seems to elevate the risks of gestational hypertension and pre-eclampsia. Many donors incur financial expenses due to factors such as lost wages, need for sick days, and travel expenses. Yet, most donors have no regrets about donation. Living kidney donation is practised ethically when informed consent incorporates information about risks, uncertainty about outcomes is acknowledged when it exists, and a donor's risks are proportional to benefits for the donor and recipient. Future research should determine whether outcomes are similar for donors from developing countries and donors with pre-existing conditions such as obesity. PMID:26090646

  20. Pregnancy and child outcome after oocyte donation.

    PubMed

    Söderström-Anttila, V

    2001-01-01

    During the last decade oocyte donation has been highly successful for treating women previously thought to be hopelessly infertile. The pregnancy rate after oocyte donation is among the highest reported for any fertility-enhancing procedure. Most investigators have noted an increased rate of obstetric complications in these pregnancies. In particular, pregnancy-induced hypertension appears to occur more often than expected, and the Caesarean section rate is high. However, the majority of oocyte recipients experience a favourable pregnancy and perinatal outcome. When perinatal complications occur they are usually related to multiple gestation. The high frequency of multiple pregnancy after oocyte donation, as well as in all other fields of assisted reproduction, deserves attention, and efforts to avoid multi-fetal gestation must be made. There are only a few studies on post-natal growth and development of young children born after oocyte donation. The health of these children appears to be within normal ranges. The psychological consequences of the treatment on the child require further investigation. Thus far, studies have shown normal socio-emotional development in the child and a warm relationship between the parents and the child in oocyte donation families. PMID:11212070

  1. Worldwide variability in deceased organ donation registries.

    PubMed

    Rosenblum, Amanda M; Li, Alvin Ho-Ting; Roels, Leo; Stewart, Bryan; Prakash, Versha; Beitel, Janice; Young, Kimberly; Shemie, Sam; Nickerson, Peter; Garg, Amit X

    2012-08-01

    The variability in deceased organ donation registries worldwide has received little attention. We considered all operating registries, where individual wishes about organ donation were recorded in a computerized database. We included registries which recorded an individual's decision to be a donor (donor registry), and registries which only recorded an individual's objection (non-donor registry). We collected information on 15 characteristics including history, design, use and number of registrants for 27 registries (68%). Most registries are nationally operated and government-owned. Registrations in five nations expire and require renewal. Some registries provide the option to make specific organ selections in the donation decision. Just over half of donor registries provide legally binding authorization to donation. In all national donor registries, except one, the proportion of adults (15+) registered is modest (<40%). These proportions can be even lower when only affirmative decisions are considered. One nation provides priority status on the transplant waiting list as an incentive to affirmative registration, while another nation makes registering a donation decision mandatory to obtain a driver's license. Registered objections in non-donor registries are rare (<0.5%). The variation in organ donor registries worldwide necessitates public discourse and quality improvement initiatives, to identify and support leading practices in registry use. PMID:22507140

  2. Payment for egg donation and surrogacy.

    PubMed

    Steinbock, Bonnie

    2004-09-01

    This article examines the ethics of egg donation. It begins by looking at objections to noncommercial gamete donation, and then takes up criticism of commercial egg donation. After discussing arguments based on concern for offspring, inequality, commodification, exploitation of donors, and threats to the family, I conclude that some payment to donors is ethically acceptable. Donors should not be paid for their eggs, but rather they should be compensated for the burdens of egg retrieval. Making the distinction between compensation for burdens and payment for a product has the advantages of limiting payment, not distinguishing between donors on the basis of their traits, and ensuring that donors are paid regardless of the number or quality of eggs retrieved. PMID:15365592

  3. Organ donation experiences of family members.

    PubMed

    Manuel, April; Solberg, Shirley; MacDonald, Sandra

    2010-01-01

    The objective of this qualitative research study was to describe and interpret what life is like for individuals who have consented to donate the organs of a deceased relative for transplantation. This study captures the meaning of this phenomenon in a way to help nurses develop new insights into the lives of these individuals, enable them to implement strategies to better assist and support the family, and perhaps decrease barriers to organ donation. Thematic analysis of the participants' narrative descriptions identified five essential themes: the struggle to acknowledge the death, the need for a positive outcome of the death, creating a living memory, buying time, and the significance of support networks in the organ donation decision. The integration of these themes revealed the essence of the experience as creating of a sense of peace. These five themes and the essence of the experience are discussed in relation to the literature, followed by recommendations for future nursing practice, education, and research. PMID:20629462

  4. Impact of a Bereavement and Donation Service incorporating mandatory 'required referral' on organ donation rates: a model for the implementation of the Organ Donation Taskforce's recommendations.

    PubMed

    Murphy, F; Cochran, D; Thornton, S

    2009-08-01

    In 2008 the Organ Donation Taskforce published its recommendations for increasing organ donation in the UK by 50% over 5 years. Bolton NHS Trust has addressed the problem of low rates of organ donation by amalgamating Bereavement and Donation Services and introducing a trigger to refer automatically all potential organ donors to the regional transplant donor co-ordinators. We audited the ability of the new service to deliver the aims and recommendations of the Organ Donation Taskforce. Following the changes in service provision the number of tissue donors rose from six in 2002 to 246 in 2007. In the same period solid organ donation rates remained unchanged. The introduction of an automatic trigger for referral of potential donors in 2007 resulted in 31 referrals and 11 successful multi-organ donors. The current service exceeds the aims of the Taskforce and offers the potential to meet UK organ donation targets without resorting to an 'opt out' system of presumed consent. PMID:19604184

  5. Incentives for organ donation: pros and cons.

    PubMed

    Chkhotua, A

    2012-01-01

    Altruism still remains the main principle of organ donation worldwide. However, since the current practices has not met the demand for organs, new strategies should be found to encourage organ donation. Implementation of financial incentives in transplantation is a matter of debate among experts in the fields of transplantation, ethics, law, and economics. It should be acknowledged that donors incur many expenses while participating in the transplant process, which seems unfair. Various forms of incentives have been suggested and are currently used worldwide. This article describes current attitudes toward incentives for in transplantation used in different countries, arguing in favor as well as against them. PMID:22841275

  6. Suicide notes and cadaveric organ donation.

    PubMed

    Behera, C; Krishna, Karthik; Kumar, R

    2016-09-01

    A suicide note is an important tool for medico-legal investigation on the manner and circumstances surrounding the death. It can also act as a facilitator for organ donation when the victim expresses their wish to do so. This article cites four examples, where the victims had specifically mentioned a "last wish" to donate their organs. The importance of such "expressed consent" in suicide notes is discussed. Such observations are not found in available scientific literature and are of importance in countries where there is a long waiting list for organ recipients and a very large number of suicidal deaths. PMID:26992402

  7. "The Tramp", a blood donation propagandist?

    PubMed

    Lefrère, J-J; Garraud, O

    2016-02-01

    The French pioneer for blood transfusion, who eventually organized the very early blood transfusion centers worldwide, went to imagine a scenario written in purpose for Charlie Chaplin, the unique character of "The Tramp" ("Charlot" in French). The movie Star was offered to feature a blood donation propagandist, and no longer the perpetual, well-known, "loser". This anecdote, besides being amusing, tells a lot on how Arnault Tzank encompassed all the difficulties in collecting blood enough to meet the demand, at all times; his proposal turns out to be extremely modern and questions nowadays marketing for blood donation. PMID:26778105

  8. FDA Approves Experimental Zika Test for Blood Donations

    MedlinePlus

    ... html FDA Approves Experimental Zika Test for Blood Donations But agency still asks those who've possibly ... HealthDay News) -- An experimental test to check blood donations for the Zika virus has been approved by ...

  9. Third Party Reproduction: Sperm, Egg, and Embryo Donation and Surrogacy

    MedlinePlus

    ... SOCIETY FOR REPRODUCTIVE MEDICINE Third-party Reproduction Sperm, egg, and embryo donation and surrogacy A Guide for ... third-party reproduction” refers to the use of eggs , sperm , or embryos that have been donated by ...

  10. 32 CFR 644.494 - Donation, abandonment or destruction.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., destroyed or donated to a public body, upon a finding in writing by the DE (but in no event shall such... justify the decision to donate, abandon, or destroy the property proposed, without outside reference....

  11. Blood Donation and Transfusion: A Primer for Health Educators.

    ERIC Educational Resources Information Center

    Felts, W. Michael; Glascoff, Mary A.

    1991-01-01

    Presents a primer for health educators about blood donation and transfusion, examining the nature of human blood, the background of blood transfusion, blood donation criteria, risks related to homologous blood transfusion, directed blood donation, potential alternatives to homologous transfusion, and resources for education on the subject. (SM)

  12. 39 CFR 777.51 - Acceptance of donations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Acceptance of donations. 777.51 Section 777.51 Postal Service UNITED STATES POSTAL SERVICE SPECIAL REGULATIONS RELOCATION ASSISTANCE AND REAL PROPERTY ACQUISITION POLICIES Donations § 777.51 Acceptance of donations. Nothing in these regulations shall prevent...

  13. 42 CFR 433.66 - Permissible provider-related donations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Permissible provider-related donations. 433.66... Requirements State Financial Participation § 433.66 Permissible provider-related donations. (a) General rule... provider-related donations without a reduction in FFP, only in accordance with the requirements of...

  14. 48 CFR 31.205-8 - Contributions or donations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Contributions or donations. 31.205-8 Section 31.205-8 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Organizations 31.205-8 Contributions or donations. Contributions or donations, including cash, property...

  15. 18 CFR 367.4261 - Account 426.1, Donations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Account 426.1, Donations. 367.4261 Section 367.4261 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY..., Donations. This account must include all payments or donations for charitable, social or community...

  16. 48 CFR 31.205-8 - Contributions or donations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Contributions or donations. 31.205-8 Section 31.205-8 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Organizations 31.205-8 Contributions or donations. Contributions or donations, including cash, property...

  17. 12 CFR 701.25 - Charitable contributions and donations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Charitable contributions and donations. 701.25... ORGANIZATION AND OPERATION OF FEDERAL CREDIT UNIONS § 701.25 Charitable contributions and donations. (a) A... directors must approve charitable contributions and/or donations, and the approval must be based on...

  18. 38 CFR 38.603 - Gifts and donations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Gifts and donations. 38...) NATIONAL CEMETERIES OF THE DEPARTMENT OF VETERANS AFFAIRS § 38.603 Gifts and donations. (a) Gifts and donations will be accepted only after it has been determined that the donor has a clear understanding...

  19. 12 CFR 701.25 - Charitable contributions and donations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Charitable contributions and donations. 701.25... ORGANIZATION AND OPERATION OF FEDERAL CREDIT UNIONS § 701.25 Charitable contributions and donations. (a) A... directors must approve charitable contributions and/or donations, and the approval must be based on...

  20. 48 CFR 31.205-8 - Contributions or donations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Contributions or donations. 31.205-8 Section 31.205-8 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Organizations 31.205-8 Contributions or donations. Contributions or donations, including cash, property...

  1. 42 CFR 433.66 - Permissible provider-related donations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Permissible provider-related donations. 433.66... Requirements State Financial Participation § 433.66 Permissible provider-related donations. (a) General rule... provider-related donations without a reduction in FFP, only in accordance with the requirements of...

  2. 38 CFR 38.603 - Gifts and donations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Gifts and donations. 38...) NATIONAL CEMETERIES OF THE DEPARTMENT OF VETERANS AFFAIRS § 38.603 Gifts and donations. (a) Gifts and donations will be accepted only after it has been determined that the donor has a clear understanding...

  3. 38 CFR 38.603 - Gifts and donations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Gifts and donations. 38...) NATIONAL CEMETERIES OF THE DEPARTMENT OF VETERANS AFFAIRS § 38.603 Gifts and donations. (a) Gifts and donations will be accepted only after it has been determined that the donor has a clear understanding...

  4. 48 CFR 31.205-8 - Contributions or donations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contributions or donations. 31.205-8 Section 31.205-8 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Organizations 31.205-8 Contributions or donations. Contributions or donations, including cash, property...

  5. 18 CFR 367.4261 - Account 426.1, Donations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Account 426.1, Donations. 367.4261 Section 367.4261 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY..., Donations. This account must include all payments or donations for charitable, social or community...

  6. 42 CFR 433.66 - Permissible provider-related donations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Permissible provider-related donations. 433.66... Requirements State Financial Participation § 433.66 Permissible provider-related donations. (a) General rule... provider-related donations without a reduction in FFP, only in accordance with the requirements of...

  7. 18 CFR 367.4261 - Account 426.1, Donations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 426.1, Donations. 367.4261 Section 367.4261 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY..., Donations. This account must include all payments or donations for charitable, social or community...

  8. 38 CFR 38.603 - Gifts and donations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Gifts and donations. 38...) NATIONAL CEMETERIES OF THE DEPARTMENT OF VETERANS AFFAIRS § 38.603 Gifts and donations. (a) Gifts and donations will be accepted only after it has been determined that the donor has a clear understanding...

  9. 18 CFR 367.4261 - Account 426.1, Donations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Account 426.1, Donations. 367.4261 Section 367.4261 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY..., Donations. This account must include all payments or donations for charitable, social or community...

  10. 42 CFR 433.66 - Permissible provider-related donations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Permissible provider-related donations. 433.66... Requirements State Financial Participation § 433.66 Permissible provider-related donations. (a) General rule... provider-related donations without a reduction in FFP, only in accordance with the requirements of...

  11. 12 CFR 701.25 - Charitable contributions and donations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Charitable contributions and donations. 701.25... ORGANIZATION AND OPERATION OF FEDERAL CREDIT UNIONS § 701.25 Charitable contributions and donations. (a) A... directors must approve charitable contributions and/or donations, and the approval must be based on...

  12. 38 CFR 38.603 - Gifts and donations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Gifts and donations. 38...) NATIONAL CEMETERIES OF THE DEPARTMENT OF VETERANS AFFAIRS § 38.603 Gifts and donations. (a) Gifts and donations will be accepted only after it has been determined that the donor has a clear understanding...

  13. 48 CFR 31.205-8 - Contributions or donations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Contributions or donations. 31.205-8 Section 31.205-8 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Organizations 31.205-8 Contributions or donations. Contributions or donations, including cash, property...

  14. 42 CFR 433.66 - Permissible provider-related donations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Permissible provider-related donations. 433.66... Requirements State Financial Participation § 433.66 Permissible provider-related donations. (a) General rule... provider-related donations without a reduction in FFP, only in accordance with the requirements of...

  15. 18 CFR 367.4261 - Account 426.1, Donations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Account 426.1, Donations. 367.4261 Section 367.4261 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY..., Donations. This account must include all payments or donations for charitable, social or community...

  16. 41 CFR 109-44.702 - Donations to public bodies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... bodies. 109-44.702 Section 109-44.702 Public Contracts and Property Management Federal Property... AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.702 Donations to public bodies....

  17. 41 CFR 109-44.702 - Donations to public bodies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... bodies. 109-44.702 Section 109-44.702 Public Contracts and Property Management Federal Property... AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.702 Donations to public bodies....

  18. 39 CFR 777.51 - Acceptance of donations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Acceptance of donations. 777.51 Section 777.51 Postal Service UNITED STATES POSTAL SERVICE SPECIAL REGULATIONS RELOCATION ASSISTANCE AND REAL PROPERTY ACQUISITION POLICIES Donations § 777.51 Acceptance of donations. Nothing in these regulations shall prevent...

  19. 32 CFR 644.495 - Donation to a public body.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Donation to a public body. 644.495 Section 644... Land) § 644.495 Donation to a public body. A public body, as defined by GSA for this purpose, means any.... Property as to which findings of fact have been made, may be donated to a public body....

  20. [Basic ethical aspects of living organ donation].

    PubMed

    Nagel, E; Mayer, J

    2003-06-01

    A characteristic feature of transplanting organs from living donors is that not only patients in need for treatment but also healthy individuals are submitted to medical interventions. Ethical considerations in this field have to deal with the question of property attributes of the human body and conflicts with traditional medical principles. Altruistic organ donation, appreciated by Christianity as a sign of charity, is indeed contradictory to the classic maxim of medical ethics "primum nihil nocere, " meaning "first of all, do not harm." The autonomous choice of a potential donor has to be balanced thoroughly against his personal physical and psychological risks. Apart from organ donation with altruistic motives, commercial incentives or payment for organ donation, which are increasingly under discussion in many nations, need profound ethical reflection. Organ selling does not lead to long-term economic benefit for individual donors in developing countries and is associated with a decline in health. A market system of organ sales would foster exploitation of the poor, and it is substantially doubtful whether autonomy and self determination are valid under circumstances of poverty and coercion. Commodification of the human body risks viewing persons as marketable objects. The human body,however, is an integral element of an individual's personality and not a resource to be removed. It is therefore fundamental that the social good of altruism is preserved as the major principle in organ donation. PMID:12883802

  1. Normative consent and organ donation: a vindication.

    PubMed

    Saunders, Ben

    2011-06-01

    In an earlier article, I argued that David Estlund's notion of 'normative consent' could provide justification for an opt-out system of organ donation that does not involve presumptions about the deceased donor's consent. Where it would be wrong of someone to refuse their consent, then the fact that they have not actually given it is irrelevant, though an explicit denial of consent (as in opting out) may still be binding. My argument has recently been criticised by Potts et al, who argue that such a policy would involve taking organs from people whose organs should not be taken and would be a recipe for totalitarianism. The present response seeks to rebut both the ethical and political objections. I argue that people can indeed be under a moral obligation to donate their organs, even if they are not technically dead at the time and their donation does not save anyone else's life. Moreover, I argue that an opt-out system-unlike mandatory donation-is not totalitarian because it preserves the right of individuals to act morally wrongly, by opting out when they have no good moral reason to do so. The policy I propose is neither immoral nor totalitarian. PMID:21429959

  2. The Path to a $300-Million Donation

    ERIC Educational Resources Information Center

    Masterson, Kathryn

    2008-01-01

    The first time Edward A. Snyder, dean of the University of Chicago's graduate business school, asked David G. Booth to donate money to name something on the campus, Mr. Booth said no. Five years later, the University's Graduate School of Business is named the University of Chicago Booth School of Business, after Mr. Booth gave what is valued as a…

  3. Nurses' role in encouraging organ donation.

    PubMed

    Shyr, S

    There is currently a shortage of transplantable organs, mainly because the relatives of potential organ donors dying in hospital are not routinely offered the choice of donating their loved one's organs. Nurses are ideally placed to perform this function, and those who have had the courage to approach relatives of potential organ donors have found it a worthwhile experience. PMID:8467192

  4. Wisconsin's Donated Food Distribution Program Handbook.

    ERIC Educational Resources Information Center

    Wisconsin State Dept. of Public Instruction, Madison. Bureau for Food and Nutrition Services.

    This handbook describes the following aspects of the operation of the U.S. Department of Agriculture Donated Food Distribution Program in Wisconsin: (1) who can participate; (2) how Wisconsin gets commodities; (3) what types of commodities are available; (4) distribution and billing procedures; (5) commodity storage; (6) commodity processing; (7)…

  5. When Opportunity Knocks Twice: Dual Living Kidney Donation, Autonomy and the Public Interest.

    PubMed

    Bailey, Phillippa; Huxtable, Richard

    2016-02-01

    Living kidney transplantation offers the best treatment in terms of life-expectancy and quality of life for those with end-stage renal disease. The long-term risks of living donor nephrectomy, although real, are very small, with evidence of good medium-term outcomes. Who should be entitled to donate, and in which circumstances, is nevertheless a live question. We explore the ethical dimensions of a request by an individual to donate both of their kidneys during life: 'dual living kidney donation'. Our ethical analysis is tethered to a hypothetical case study in which a father asks to donate a kidney to each of his twin boys. We explore the autonomy of the protagonists, alongside different dimensions of the public interest, such as the need to protect not only the recipients, but also the donor and even the wider community. Whilst acknowledging objections to 'dual-donation', not least by reference to the harms that the donor might be expected to endure, we suggest there is a prima facie case for permitting this, provided that both donor and recipients are willing and that due attention is paid to such considerations as the autonomy and welfare of all parties, as well as to the wider ramifications of acting on such a request. We argue for broader interpretations of the concepts of autonomy and welfare, recognizing the importance of relationships and the relevance of more than merely physical well-being. Equipped with such a holistic assessment, we suggest there is a prima facie case for allowing 'dual living kidney donation'. PMID:26194324

  6. Does financial compensation for living kidney donation change willingness to donate?

    PubMed

    Gordon, E J; Patel, C H; Sohn, M-W; Hippen, B; Sherman, L A

    2015-01-01

    The potential use of financial compensation to increase living kidney donation rates remains controversial in potentially introducing undue inducement of vulnerable populations to donate. This cross-sectional study assessed amounts of financial compensation that would generate motivation and an undue inducement to donate to family/friends or strangers. Individuals leaving six Departments of Motor Vehicles were surveyed. Of the 210 participants who provided verbal consent (94% participation rate), respondents' willingness to donate would not change (70%), or would increase (29%) with compensation. Median lowest amounts of financial compensation for which participants would begin to consider donating a kidney were $5000 for family/friends, and $10,000 for strangers; respondents reporting $0 for family/friends (52%) or strangers (26%) were excluded from analysis. Median lowest amounts of financial compensation for which participants could no longer decline (perceive an undue inducement) were $50,000 for family/friends, and $100,000 for strangers; respondents reporting $0 for family/friends (44%) or strangers (23%) were excluded from analysis. The two most preferred forms of compensation included: direct payment of money (61%) and paid leave (21%). The two most preferred uses of compensation included: paying off debt (38%) and paying nonmedical expenses associated with the transplant (29%). Findings suggest tolerance for, but little practical impact of, financial compensation. Certain compensation amounts could motivate the public to donate without being perceived as an undue inducement. PMID:25425398

  7. Donor motivations, associated risks and ethical considerations of oocyte donation.

    PubMed

    Boutelle, Amy L

    2014-01-01

    Three decades after the first reported successful cases, oocyte donation continues to grow in popularity and regard as an established method to aid women in achieving their reproductive goals. As a result of the increased demand for donated oocytes, many young women in the U.S. volunteer to undergo complex medical procedures to donate their oocytes in return for financial compensation. To best care for these women before, during and after donation, it is important to explore donor characteristics and motivations, discuss the safety of the donation procedure and examine the ethical issues related to this process. PMID:24750650

  8. Cyclooxygenase-inhibiting nitric oxide donators for osteoarthritis.

    PubMed

    Wallace, John L; Viappiani, Serena; Bolla, Manlio

    2009-03-01

    Nonsteroidal anti-inflammatory drugs (NSAIDs) remain the most commonly used medications for the treatment of the symptoms of many chronic inflammatory diseases, including osteoarthritis. Unfortunately, the toxicity of NSAIDs substantially limits their long-term use. Some newer NSAIDs, namely selective cyclooxygenase (COX)-2 inhibitors, exhibit greater gastrointestinal safety, and concomitant use of anti-secretory drugs can also reduce NSAID-induced gastropathy. However, NSAIDs also adversely affect the cardiovascular system. A new class of anti-inflammatory drugs, COX-inhibiting nitric oxide donators (CINODs), has been designed to exert similar anti-inflammatory effects as NSAIDs, but with an improved safety profile. CINODs release nitric oxide, providing protective effects in the gastrointestinal tract and attenuating the detrimental effects on blood pressure normally associated with NSAIDs. We provide an outline of the rationale for CINODs and their activity, in addition to an overview of the pre-clinical and clinical profile of the most advanced CINOD, naproxcinod. PMID:19230986

  9. Ethical issues surrounding the use of images from donated cadavers in the anatomical sciences.

    PubMed

    Cornwall, Jon; Callahan, David; Wee, Richman

    2016-01-01

    Body donor programs rely on the generosity and trust of the public to facilitate the provision of cadaver resources for anatomical education and research. The uptake and adoption of emerging technologies, including those allowing the acquisition and distribution of images, are becoming more widespread, including within anatomical science education. Images of cadavers are useful for research and education, and their supply and distribution have commercial potential for textbooks and online education. It is unclear whether the utilization of images of donated cadavers are congruent with donor expectations, societal norms and boundaries of established public understanding. Presently, no global "best practices" or standards exist, nor is there a common model requiring specific image-related consent from body donors. As ongoing success of body donation programs relies upon the ethical and institutional governance of body utilization to maintain trust and a positive relationship with potential donors and the community, discussions considering the potential impact of image misuse are important. This paper discusses the subject of images of donated cadavers, commenting on images in non-specific use, education, research, and commercial applications. It explores the role and significance of such images in the context of anatomical science and society, and discusses how misuse - including unconsented use - of images has the potential to affect donor program success, suggesting that informed consent is currently necessary for all images arising from donated cadavers. Its purpose is to encourage discussion to guide responsible utilization of cadaver images, while protecting the interests of body donors and the public. PMID:26474731

  10. Options for the disposal of unwanted donations.

    PubMed Central

    Cooper, E R

    1990-01-01

    Donations of biomedical books and journals frequently duplicate the holdings of a receiving library. A decision must then be made concerning the distribution of the material to other libraries that may need it. What options are available to the librarian? Are many volumes of valuable material destroyed each year because libraries lack the necessary staff, space, or money to distribute donated materials? Are libraries restricted in choice of methods for distribution or unaware of available options? A survey questionnaire was mailed to 150 health sciences libraries in the spring of 1988 to determine the various methods used to dispose of unwanted gift materials. A total of 113 responses was received (75% return rate). This paper reports the results and discusses some of the creative methods used by receiving libraries to place unneeded materials. Statistical comparisons are included for the methods used by academic, hospital, and other types of health sciences libraries. Images PMID:2224303

  11. Defining embryo donation: an Ethics Committee opinion.

    PubMed

    2016-07-01

    Building families through the adoption of children has been supported by human society throughout history. The ethical appropriateness of patients donating embryos to other patients for family building, or for research, is well established and is affirmed by this Committee. The use of the term ''adoption'' for embryos is inaccurate and should be avoided. This document replaces the ASRM Ethics Committee statement by the same name, last published in 2013 (Fertil Steril 2013;99:1846-7). PMID:27001380

  12. Donate Food to Free Your Boss | Poster

    Cancer.gov

    For the third year in a row, NCI at Frederick is participating in the Feds Feed Families campaign, which aims to stock food banks during the summer when donations are often limited. The 2016 campaign runs through August 31. This year, the Office of Scientific Operations (OSO) has decided to send the campaign off with a twist. Rich Folkers, public affairs specialist, Office of Scientific Operations, came up with the idea for a "lock-in" event.

  13. [Marketing in the world of blood donation].

    PubMed

    Daigneault, Sylvie

    2007-05-01

    Public and non-profit organizations have long debated how marketing concepts and management styles apply to their sector of activity as they are largely derived from principles of consumerism and economic decision-making proper to the private sector. The arrival of marketing in the world of blood donation is no exception. The purpose of this article is to illustrate concretely how marketing techniques can contribute in achieving the objectives of a blood donation program: a marketing model that is adapted to the realities of blood donation in Quebec. Although types of marketing are as varied as the fields they are used in, the major marketing activities of this program fall under positioning, operational or relationship marketing. The process is presented in the form of a cycle that includes four major phases containing all marketing functions, that is, raising public awareness, acquiring a clientele, client retention and loyalty building, and establishing the relationship. Finally, the information and effective management of information are at the heart of the marketing process. In fact, research, understanding our customers and their expectations, and measuring our performance are essential for the success of any marketing initiative. PMID:17524694

  14. The emotional cost of charitable donations.

    PubMed

    Rubaltelli, Enrico; Agnoli, Sergio

    2012-01-01

    Donations in support of a charitable cause can create a conflict between moral intuitions (e.g., fulfilling moral obligations and helping as many individuals in need as possible) and the cost entailed by following one's moral intuitions (e.g., spending money). The present paper investigates this conflict by putting people in a situation in which they must choose whether to help three women by giving more money or help one woman by giving less. In addition, the paper uses the attraction effect paradigm to counteract the single victim effect and reduce the conflict. Experiment 1 demonstrates that in a two-alternative context the majority of participants choose to help one woman by giving €150 instead of helping three women by giving €450. Experiment 2 replicates this finding and highlights the role of emotion regulation strategies in the management of the emotional conflict arising in the two-alternative condition. In both studies, the introduction of a third, dominated alternative reduces the conflict and makes it easier to choose the programme asking for a higher donation and helping three women. Implications for charitable donations and the role of the conflict between moral intuitions and economic costs are discussed. PMID:22077801

  15. Transfusion and blood donation in comic strips.

    PubMed

    Lefrère, Jean-Jacques; Danic, Bruno

    2013-07-01

    The representation of blood transfusion and donation of blood in the comic strip has never been studied. The comic strip, which is a relatively recent art, emerged in the 19th century before becoming a mass medium during the 20th century. We have sought, by calling on collectors and using the resources of Internet, comic strips devoted, wholly or in part, to the themes of transfusion and blood donation. We present some of them here in chronologic order, indicating the title, country of origin, year of publication, and names of authors. The theme of the superhero using transfusion to transmit his virtues or his powers is repeated throughout the 20th century in North American comic strips. More recently, comic strips have been conceived from the outset with a promotional aim. They perpetuate positive images and are directed toward a young readership, wielding humor to reduce the fear of venipuncture. Few comic strips denounce the abuse of the commercialization of products derived from the human body. The image of transfusion and blood donation given by the comic strips is not to be underestimated because their readership is primarily children, some of whom will become blood donors. Furthermore, if some readers are transfused during their lives, the impact of a memory more or less conscious of these childhood readings may resurface, both in hopes and in fears. PMID:23643789

  16. Can donated media placements reach intended audiences?

    PubMed

    Cooper, Crystale Purvis; Gelb, Cynthia A; Chu, Jennifer; Polonec, Lindsey

    2013-09-01

    Donated media placements for public service announcements (PSAs) can be difficult to secure, and may not always reach intended audiences. Strategies used by the Centers for Disease Control and Prevention's (CDC) Screen for Life: National Colorectal Cancer Action Campaign (SFL) to obtain donated media placements include producing a diverse mix of high-quality PSAs, co-branding with state and tribal health agencies, securing celebrity involvement, monitoring media trends to identify new distribution opportunities, and strategically timing the release of PSAs. To investigate open-ended recall of PSAs promoting colorectal cancer screening, CDC conducted 12 focus groups in three U.S. cities with men and women either nearing age 50 years, when screening is recommended to begin, or aged 50-75 years who were not in compliance with screening guidelines. In most focus groups, multiple participants recalled exposure to PSAs promoting colorectal cancer screening, and most of these individuals reported having seen SFL PSAs on television, in transit stations, or on the sides of public buses. Some participants reported exposure to SFL PSAs without prompting from the moderator, as they explained how they learned about the disease. Several participants reported learning key campaign messages from PSAs, including that colorectal cancer screening should begin at age 50 years and screening can find polyps so they can be removed before becoming cancerous. Donated media placements can reach and educate mass audiences, including millions of U.S. adults who have not been screened appropriately for colorectal cancer. PMID:23720533

  17. Spermine and spermidine inhibition of photosystem II: Disassembly of the oxygen evolving complex and consequent perturbation in electron donation from TyrZ to P680+ and the quinone acceptors QA- to QB.

    PubMed

    Beauchemin, Rémy; Gauthier, Alain; Harnois, Johanne; Boisvert, Steve; Govindachary, Sridharan; Carpentier, Robert

    2007-07-01

    Polyamines are implicated in plant growth and stress response. However, the polyamines spermine and spermidine were shown to elicit strong inhibitory effects in photosystem II (PSII) submembrane fractions. We have studied the mechanism of this inhibitory action in detail. The inhibition of electron transport in PSII submembrane fractions treated with millimolar concentrations of spermine or spermidine led to the decline of plastoquinone reduction, which was reversed by the artificial electron donor diphenylcarbazide. The above inhibition was due to the loss of the extrinsic polypeptides associated with the oxygen evolving complex. Thermoluminescence measurements revealed that charge recombination between the quinone acceptors of PSII, QA and QB, and the S2 state of the Mn-cluster was abolished. Also, the dark decay of chlorophyll fluorescence after a single turn-over white flash was greatly retarded indicating a slower rate of QA- reoxidation. PMID:17511958

  18. Addressing Consent Issues in Donation After Circulatory Determination of Death.

    PubMed

    Overby, Kim J; Weinstein, Michael S; Fiester, Autumn

    2015-01-01

    Given the widening gap between the number of individuals on transplant waiting lists and the availability of donated organs, as well as the recent plateau in donations based on neurological criteria (i.e., brain death), there has been a growing interest in expanding donation after circulatory determination of death. While the prevalence of this form of organ donation continues to increase, many thorny ethical issues remain, often creating moral distress in both clinicians and families. In this article, we address one of these issues, namely, the challenges surrounding patient and surrogate informed consent for donation after circulatory determination of death. First we discuss several general concerns regarding consent related to this form of organ donation, and then we address additional issues that are unique to three different patient categories: adult patients with medical decision-making capacity or potential capacity, adult patients who lack capacity, and pediatric patients. PMID:26225503

  19. Possible association of a reduction in cardiovascular events with blood donation.

    PubMed Central

    Meyers, D. G.; Strickland, D.; Maloley, P. A.; Seburg, J. K.; Wilson, J. E.; McManus, B. F.

    1997-01-01

    BACKGROUND: The iron hypothesis suggests that females are protected from atherosclerosis by having lower iron stores than men, thus limiting oxidation of lipids. OBJECTIVE: To test the iron hypothesis by comparing cardiovascular event rates in whole blood donors compared with nondonors. DESIGN: Prospective cohort with telephone survey follow up. SETTING: The State of Nebraska, USA. PARTICIPANTS: A sample was selected from the Nebraska Diet Heart Survey (NDHS) restricting for age > or = 40 years and absence of clinically apparent vascular diseases at time of enrollment in to NDHS (1985-87). MAIN OUTCOME MEASURES: The occurrence of cardiovascular events (myocardial infarction, angina, stroke), procedures (angioplasty, bypass surgery, claudication, endarterectomy), nitroglycerin use, or death (all cause mortality), and level of blood donation. RESULTS: Participants were 655 blood donors and 3200 non-donors who differed in education, physical activity, diabetes, and frequency of antihypertensive treatment; 889 were lost to follow up. Sixty four donors and 567 non-donors reported cardiovascular events (crude odds ratio = 0.50, 95% confidence interval (CI) 0.38-0.66). The benefit of donation was confined to non-smoking males (adjusted odds ratio 0.67, 95% CI 0.45-0.99). Benefit was limited to current donors (the most recent three years). No additional benefit resulted from donating more than once or twice over three years. CONCLUSION: In support of the iron hypothesis, blood donation in non-smoking men in this cohort was associated with reduced risk of cardiovascular events. A randomised clinical trial is warranted to confirm these findings as the observed personal health benefit of donation has public policy ramifications. PMID:9326996

  20. Attitudes toward organ donation and transplantation. A model for understanding reactions to medical procedures after death.

    PubMed

    Sanner, M

    1994-04-01

    The main purpose of this study was to reach a deeper understanding of factors influencing the attitudes toward organ donation and other procedures with the dead body. From a survey of 400 inhabitants of Uppsala, a city in the middle of Sweden, concerning attitudes toward transplantation issues, 38 individuals with different attitudes toward donation of their own organs were selected for follow-up interviews. From the interviews, more than 600 statements concerning motives and reactions to medical procedures with the dead body were listed. These statements were summarized in 20 motive categories, in which 17 the nature of the motives were negative to organ donation and three promoting such a procedure. The categories were then analyzed and interpreted within a frame of reference of psychodynamic defense theory. In several cases it was possible to relate them to common death anxiety defenses. Six different motive complexes were extracted. These are called (1) illusion of lingering life; (2) protection of the value of the individual; (3) distrust, anxiety and alienation; (4) respecting the limits set by Nature or God; (5) altruism; and (6) rationality. Individuals not willing to donate their own organs were judged as either (a) reacting out of strenthened death anxiety defenses, or (b) as having a special outlook on life, where the idea of what is 'natural' was emphasized. The adverse reactions of the positive attitude group were seen as initial reactions perceived as derivations of common death anxiety defenses and weakened when confronted with altruistic and fact-stressing arguments. In the 'undecided group' of 14 persons, 11 arrived at a definite opinion. Seven decided for organ donation when their mistaken beliefs were corrected or when they took time to work through their initial uneasiness, while 4 persons actually were clearly negative. Three still remained uncertain. The stability of these attitudes seems to be high, often being experienced as a part of one

  1. 41 CFR 102-37.45 - How long is property available for donation screening?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... available for donation screening? 102-37.45 Section 102-37.45 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.45 How long is property available for donation screening? Entities authorized to participate in the donation program...

  2. 41 CFR 102-37.35 - Who handles the donation of surplus property?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Who handles the donation...-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.35 Who handles the donation of surplus property? (a) The SASPs handle the donation of most surplus property to eligible...

  3. 41 CFR 102-37.30 - When does property become available for donation?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... become available for donation? 102-37.30 Section 102-37.30 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.30 When does property become available for donation? Excess personal property becomes available for donation the...

  4. 41 CFR 102-37.45 - How long is property available for donation screening?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... available for donation screening? 102-37.45 Section 102-37.45 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.45 How long is property available for donation screening? Entities authorized to participate in the donation program...

  5. 41 CFR 102-37.520 - What is the authority for public airport donations?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... for public airport donations? 102-37.520 Section 102-37.520 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Airports § 102-37.520 What is the authority for public airport donations? The authority for public airport donations is 49 U.S.C. 47151. 49...

  6. 41 CFR 102-37.520 - What is the authority for public airport donations?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... for public airport donations? 102-37.520 Section 102-37.520 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Airports § 102-37.520 What is the authority for public airport donations? The authority for public airport donations is 49 U.S.C. 47151. 49...

  7. 41 CFR 102-37.30 - When does property become available for donation?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... become available for donation? 102-37.30 Section 102-37.30 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.30 When does property become available for donation? Excess personal property becomes available for donation the...

  8. 41 CFR 102-37.35 - Who handles the donation of surplus property?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Who handles the donation...-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.35 Who handles the donation of surplus property? (a) The SASPs handle the donation of most surplus property to eligible...

  9. 41 CFR 102-37.30 - When does property become available for donation?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... become available for donation? 102-37.30 Section 102-37.30 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.30 When does property become available for donation? Excess personal property becomes available for donation the...

  10. 41 CFR 102-37.30 - When does property become available for donation?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... become available for donation? 102-37.30 Section 102-37.30 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.30 When does property become available for donation? Excess personal property becomes available for donation the...

  11. 41 CFR 102-37.35 - Who handles the donation of surplus property?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Who handles the donation...-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.35 Who handles the donation of surplus property? (a) The SASPs handle the donation of most surplus property to eligible...

  12. 41 CFR 102-37.520 - What is the authority for public airport donations?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... for public airport donations? 102-37.520 Section 102-37.520 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Airports § 102-37.520 What is the authority for public airport donations? The authority for public airport donations is 49 U.S.C. 47151. 49...

  13. 41 CFR 102-37.520 - What is the authority for public airport donations?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... for public airport donations? 102-37.520 Section 102-37.520 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Airports § 102-37.520 What is the authority for public airport donations? The authority for public airport donations is 49 U.S.C. 47151. 49...

  14. 41 CFR 102-37.30 - When does property become available for donation?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... become available for donation? 102-37.30 Section 102-37.30 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.30 When does property become available for donation? Excess personal property becomes available for donation the...

  15. 41 CFR 102-37.45 - How long is property available for donation screening?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... available for donation screening? 102-37.45 Section 102-37.45 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.45 How long is property available for donation screening? Entities authorized to participate in the donation program...

  16. 41 CFR 102-37.520 - What is the authority for public airport donations?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for public airport donations? 102-37.520 Section 102-37.520 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Airports § 102-37.520 What is the authority for public airport donations? The authority for public airport donations is 49 U.S.C. 47151. 49...

  17. Awareness of Religious Leaders’ Fatwa and Willingness to Donate Organ

    PubMed Central

    Afzal Aghaee, M.; Dehghani, M.; Sadeghi, M.; Khaleghi, E.

    2015-01-01

    Background: It is believed that religious leaders’ positive attitude towards organ donation can be an effective factor in Muslims’ inclination to donate organs. Objective: To assess the knowledge of freshmen students in Mashhad University of Medical Sciences about religious leaders’ fatwa on organ donation and its effect on their willingness to donate organs. Methods: This cross-sectional study was conducted in 2013 on 400 freshmen of various medical disciplines, selected using a simple random sampling in Mashhad, Iran. Data were collected by a valid and reliable researcher-made questionnaire. Data were analyzed by multiple logistic regression analysis. Results: 41.5% of the students were aware of religious authorities’ views on organ donation and 55.6% were willing to donate organs. Participants’ main reasons for lack of willingness to donate organs included the fear of organ donation before the brain death is confirmed (52%), unwillingness to disfigure their body (51%), and belief in the burial of organs (50%). The willingness to organ donation for students who were aware of religious leaders opinion was more than twice more than those who were not (OR: 2.56, 95% CI: 1.75–4.52). Also, female gender, the Shia religion and awareness of the correct definition of brain death were associated factors affecting the desire to donate organs, although their effects were not statistically significant on regression model. Conclusion: A considerable proportion of students were not aware of the religious leaders’ fatwa on organ donation. The most important factor for the desire to donate organs was the awareness of religious leaders’ fatwa. Therefore, it seems necessary that religious leaders’ fatwa be known to all by appropriate methods. PMID:26576261

  18. UK policy initiatives and the effect on increasing organ donation.

    PubMed

    Hall, Bethany; Parkin, Matthew Sw

    Organ donation has developed since the Human Tissue Act 1961, and even since the Human Tissue Act 2004, which replaced it. Given the demand for organ transplants, there have been various attempts to increase the number of people on the Organ Donation Register, including awareness campaigns and celebrity endorsement. However, as the UK-wide strategy Taking Organ Transplantation to 2020 indicates, increasing the number of donations will require more than simply increasing the number of registered donors. This article reviews the changes in policies relating to organ donation and the associated issues. PMID:27019167

  19. Can we create ethnically diverse skeletal collection from donated bodies?

    PubMed

    Weiss, Elizabeth

    2015-01-01

    Understanding bone health is least invasively and most effectively done through studying skeletal remains that reflect the living populations who will benefit from the knowledge produced through research. Donated body collections that accurately represent modern populations are needed for osteological insights to be applied to clinical practices. However, even though the US is growing increasingly diverse, donated body collections still suffer from a lack of ethnic diversity. Most individuals who donate their whole-bodies after death are European-American. Reasons for a lack of ethnic diversity stem from past injustices and present religious norms. Increasing body donation among minorities in the US and abroad may be difficult. PMID:25775919

  20. Financial compensation for deceased organ donation in China.

    PubMed

    Wu, Xiaoliang; Fang, Qiang

    2013-06-01

    In March 2010, China launched a pilot programme of deceased donor organ donation in 10 provinces and cities. However, the deceased donor donation rate in China remains significantly lower than in Spain and other Western countries. In order to provide incentive for deceased donor organ donation, five pilot provinces and cities have subsequently launched a financial compensation policy. Financial compensation can be considered to include two main forms, the 'thank you' form and the 'help' form. The 'thank you' form is an expression of gratitude on behalf of the Red Cross Society of China for consenting to donation. The 'help' form is social welfare support for needy families. PMID:23322684

  1. Altruism and reward: motivational compatibility in deceased organ donation.

    PubMed

    Voo, Teck Chuan

    2015-03-01

    Acts of helping others are often based on mixed motivations. Based on this claim, it has been argued that the use of a financial reward to incentivize organ donation is compatible with promoting altruism in organ donation. In its report Human Bodies: Donation for Medicine and Research, the Nuffield Council on Bioethics uses this argument to justify its suggestion to pilot a funeral payment scheme to incentivize people to register for deceased organ donation in the UK. In this article, I cast a sceptical eye on the above Nuffield report's argument that its proposed funeral payment scheme would prompt deceased organ donations that remain altruistic (as defined by and valued the report). Specifically, I illustrate how this scheme may prompt various forms of mixed motivations which would not satisfy the report's definition of altruism. Insofar as the scheme produces an expectation of the reward, it stands diametrical to promoting an 'altruistic perspective'. My minimal goal in this article is to argue that altruism is not motivationally compatible with reward as an incentive for donation. My broader goal is to argue that if a financial reward is used to incentivize organ donation, then we should recognize that the donation system is no longer aiming to promote altruism. Rewarded donation would not be altruistic but it may be ethical given a persistent organ shortage situation. PMID:24547770

  2. Nurses' attitudes toward organ donation: an Australian perspective.

    PubMed

    Duke, J; Murphy, B; Bell, A

    1998-01-01

    Australia's rate of organ donation, which has shown a continuing downward trend, is among the lowest in the developed world. Research has demonstrated that nurses' attitudes and behaviors are important functions in organ donation, particularly retrieval. This study investigated the attitudes and knowledge levels about organ donation of paediatric nurses in a large metropolitan children's hospital and nurses in two rural hospitals. The results highlight the role that critical care nurses and advanced practice nurses need to play in improving levels of organ donation. PMID:10639986

  3. From fresh heterologous oocyte donation to autologous oocyte banking

    PubMed Central

    Stoop, D.

    2012-01-01

    Introduction: Today, oocyte donation has become well established, giving rise to thousands of children born worldwide annually. The introduction of oocyte cryopreservation through vitrification allows the introduction of egg banking, improving the efficiency and comfort of oocyte donation. Moreover, the vitrification technique can now enable autologous donation of oocytes to prevent future infertility. Methods: We evaluated fresh heterologous oocyte donation in terms of obstetrical and perinatal outcome as well as of the reproductive outcome of past donors. We then evaluated the efficiency of a closed vitrification device and its clinical applications within ART. Thirdly, we evaluated the opinion of women with regard to preventive egg freezing and the efficiency of a human oocyte in relation to age. Results: Oocyte donation is associated with an increased risk of first trimester bleeding and pregnancy induced hypertension. Donating oocytes does not seem to increase the likelihood for a later need of fertility treatment. The chance of an oocyte to result in live birth (utilization rate) in women <37 years old remains constant with a mean of 4.47%. A significant proportion of young women would consider safeguarding their reproductive potential through egg freezing or are at least open to the idea. Discussion and Conclusion: The introduction of efficient oocyte cryopreservation has revolutionized oocyte donation through the establishment of eggbank donation. The technique also enables women to perform autologous donation after preventive oocyte storage in order to circumvent their biological clock. PMID:24753920

  4. What Is Being Done to Increase Organ Donation?

    PubMed

    Scheuher, Cynthia

    2016-01-01

    The need for organs greatly outnumbers the amount of organs donated for transplantation. This is true for all countries around the world. Many organizations globally have been created to solve this problem. Spain has been very successful with its drive to increase organ donation. Educational campaigns are a great tool being utilized by all countries and the medical communities to promote a positive perception of organ donation. These campaigns include using the television industry, raising money for travel expenses, and education seminars. This article looks at the different groups and programs aimed at increasing organ donation. PMID:27254645

  5. Donation after cardiac death in abdominal organ transplantation.

    PubMed

    Reich, David J; Guy, Stephen R

    2012-01-01

    This article reviews the field of donation after cardiac death, focusing on the history, ethicolegal issues, clinical outcomes, best practices, operative techniques, and emerging strategies to optimize utilization of this resource. Donation after cardiac death is one effective way to decrease the organ shortage and has contributed the largest recent increase in abdominal organ allografts. Currently, donation after cardiac death organs confer an increased risk of ischemic cholangiopathy after liver transplant and of delayed graft function after kidney transplant. As this field matures, risk factors for donation after cardiac death organ transplant will be further identified and clinical outcomes will improve as a result of protocol standardization and ongoing research. PMID:22678860

  6. A qualitative analysis of a significant barrier to organ and tissue donation: receiving less-than-optimal medical care.

    PubMed

    Denvir, Paul; Pomerantz, Anita

    2009-10-01

    A key reason for the shortage of transplantable organs and tissue in the United States is the degree of resistance among the public to donating organs and tissue after death. In this article, we explore a single barrier to donation: the concern that medical personnel might provide "less-than-optimal" care to intended donors. Using 2 qualitative methodologies-analysis of family discussions about donation and analysis of in-depth interviews about donation-we explore what participants' discourse reveals about the variations and texture of this concern. The analysis revealed 4 aspects of this concern: (a) Participants expressed different versions of less-than-optimal care, each reflecting different assumptions about how medical personnel may approach the treatment of potential donors. (b) Participants expressed their concerns by describing hypothetical scenarios of medical treatment. These scenarios were designed to play up the plausibility of receiving less-than-optimal care and situated the speaker as the victim in the scenario. (c) Participants' uncertainty about the quality of medical treatment was sufficient grounds for not donating. (d) Participants expressed their concerns about medical treatment in terms of the perceived corruptibility of sociocultural institutions, including medical institutions. This analysis also revealed the lines of reasoning through which participants overcame a concern about receiving less-than-optimal-care. In our view, the most promising line of reasoning expressed by participants was to trust the legal and procedural protections built into the recovery process. PMID:20183368

  7. IMPIPS: The Immune Protection-Inducing Protein Structure Concept in the Search for Steric-Electron and Topochemical Principles for Complete Fully-Protective Chemically Synthesised Vaccine Development

    PubMed Central

    Patarroyo, Manuel Elkin; Bermúdez, Adriana; Alba, Martha Patricia; Vanegas, Magnolia; Moreno-Vranich, Armando; Poloche, Luis Antonio; Patarroyo, Manuel Alfonso

    2015-01-01

    Determining immune protection-inducing protein structures (IMPIPS) involves defining the stereo-electron and topochemical characteristics which are essential in MHC-p-TCR complex formation. Modified high activity binding peptides (mHABP) were thus synthesised to produce a large panel of IMPIPS measuring 26.5 ±3.5Å between the farthest atoms fitting into Pockets 1 to 9 of HLA-DRβ1* structures. They displayed a polyproline II-like (PPIIL) structure with their backbone O and N atoms orientated to establish H-bonds with specific residues from HLA-DRβ1*-peptide binding regions (PBR). Residues having specific charge and gauche+ orientation regarding p3χ1, p5χ2, and p7χ1 angles determined appropriate rotamer orientation for perfectly fitting into the TCR to induce an appropriate immune response. Immunological assays in Aotus monkeys involving IMPIPS mixtures led to promising results; taken together with the aforementioned physicochemical principles, non-interfering, long-lasting, protection-inducing, multi-epitope, multistage, minimal subunit-based chemically-synthesised peptides can be designed against diseases scourging humankind. PMID:25879751

  8. IMPIPS: the immune protection-inducing protein structure concept in the search for steric-electron and topochemical principles for complete fully-protective chemically synthesised vaccine development.

    PubMed

    Patarroyo, Manuel Elkin; Bermúdez, Adriana; Alba, Martha Patricia; Vanegas, Magnolia; Moreno-Vranich, Armando; Poloche, Luis Antonio; Patarroyo, Manuel Alfonso

    2015-01-01

    Determining immune protection-inducing protein structures (IMPIPS) involves defining the stereo-electron and topochemical characteristics which are essential in MHC-p-TCR complex formation. Modified high activity binding peptides (mHABP) were thus synthesised to produce a large panel of IMPIPS measuring 26.5 ±3.5Å between the farthest atoms fitting into Pockets 1 to 9 of HLA-DRβ1* structures. They displayed a polyproline II-like (PPIIL) structure with their backbone O and N atoms orientated to establish H-bonds with specific residues from HLA-DRβ1*-peptide binding regions (PBR). Residues having specific charge and gauche+ orientation regarding p3χ1, p5χ2, and p7χ1 angles determined appropriate rotamer orientation for perfectly fitting into the TCR to induce an appropriate immune response. Immunological assays in Aotus monkeys involving IMPIPS mixtures led to promising results; taken together with the aforementioned physicochemical principles, non-interfering, long-lasting, protection-inducing, multi-epitope, multistage, minimal subunit-based chemically-synthesised peptides can be designed against diseases scourging humankind. PMID:25879751

  9. Donating in good faith or getting into trouble Religion and organ donation revisited

    PubMed Central

    Oliver, Mike; Ahmed, Aimun; Woywodt, Alexander

    2012-01-01

    There is worldwide shortage of organs for solid-organ transplantation. Many obstacles to deceased and live donation have been described and addressed, such as lack of understanding of the medical process, the issue of the definition of brain death, public awareness of the need for transplants, and many others. However, it is clear that the striking differences in deceased and live donation rates between different countries are only partly explained by these factors and many cultural and social reasons have been invoked to explain these observations. We believe that one obstacle to both deceased and live donation that is less well appreciated is that of religious concerns. Looking at the major faiths and religions worldwide, it is reassuring to see that most of them encourage donation. However, there is also scepticism amongst some of them, often relating to the concept of brain death and/or the processes surrounding death itself. It is worthwhile for transplant teams to be broadly aware of the issues and also to be mindful of resources for counselling. We believe that increased awareness of these issues within the transplant community will enable us to discuss these openly with patients, if they so wish. PMID:24175198

  10. Incentives for organ donation: some ethical issues.

    PubMed

    Sells, Robert

    2004-01-01

    Objections to commerce in organs has not stopped the spread of such practice around the world. In most countries the gap between supply and demand for organs continues to increase. Kidneys from living donors are considered a valuable addition to the donor pool, and in a more acquisitive world, donor incentives are becoming thinkable, even acceptable. Current incentives for cadaver and living organ donation are reviewed from ethical and legal perspectives. A new principle of reimbursement for the living donor's risk and pain is defined and presented for debate. PMID:15478883

  11. Organ donation: a twin-based perspective.

    PubMed

    Segal, Nancy L

    2012-04-01

    Monozygotic cotwins are ideal organ donors for one another due to their genetic identity. The present report treats this topic differently, from the perspective of a monozygotic twin who donated her deceased twin sister's organs following her sister's untimely death. This discussion is followed by reviews of recent research concerning increased twinning rates in the United States, availability of informative kinship pedigrees, and twin discordance for physical activities. Noteworthy news items include ethical issues surrounding conjoined twin separation, a genomic discovery for diseased twins, China's One-Child Policy, a striking New Yorker Magazine cartoon, and twin delivery complications. PMID:22856360

  12. Organ donation: a significant marketing challenge.

    PubMed

    Clarke, Roberta N

    2007-01-01

    Unlike most health care markets, the organ donation market is one where patients are the marketers, prospective donors are the customers, and no payment is allowed in the exchange process. The assumption that altruistic behavior by donors would satisfy the need for organs has proven woefully untrue. As a result, those needing organs have resorted to relying on unwilling or impoverished donors, to having to promote themselves on websites which have achieved success for only small numbers of patients, or to waiting for organs which they may never receive. This remains a still unsolved marketing challenge. PMID:19042535

  13. Overview of the organ donation process.

    PubMed

    Albert, P L

    1994-09-01

    Organ transplantation has become a viable treatment option for end-stage organ disease. With the advent of immunosuppressive medication and vastly improved preservation practices and surgical techniques, it is now possible to transplant an increasing number and variety of organs. In their role as direct care givers to patients and their families, critical care nurses must be attuned to the need for donor organs and tissues, and to the benefits of donation for the donor family, the potential organ recipients, and to themselves as health care professionals. PMID:7946210

  14. Impact of presumed consent for organ donation on donation rates: a systematic review

    PubMed Central

    Rithalia, Amber; Suekarran, Sara; Myers, Lindsey; Sowden, Amanda

    2009-01-01

    Objectives To examine the impact of a system of presumed consent for organ donation on donation rates and to review data on attitudes towards presumed consent. Design Systematic review. Data sources Studies retrieved by online searches to January 2008 of Medline, Medline In-Process, Embase, CINAHL, PsycINFO, HMIC, PAIS International, and OpenSIGLE. Studies reviewed Five studies comparing donation rates before and after the introduction of legislation for presumed consent (before and after studies); eight studies comparing donation rates in countries with and without presumed consent systems (between country comparisons); 13 surveys of public and professional attitudes to presumed consent. Results The five before and after studies represented three countries: all reported an increase in donation rates after the introduction of presumed consent, but there was little investigation of any other changes taking place concurrently with the change in legislation. In the four best quality between country comparisons, presumed consent law or practice was associated with increased organ donation—increases of 25-30%, 21-26%, 2.7 more donors per million population, and 6.14 more donors per million population in the four studies. Other factors found to be important in at least one study were mortality from road traffic accidents and cerebrovascular causes, transplant capacity, gross domestic product per capita, health expenditure per capita, religion (Catholicism), education, public access to information, and a common law legal system. Eight surveys of attitudes to presumed consent were of the UK public. These surveys varied in the level of support for presumed consent, with surveys conducted before 2000 reporting the lowest levels of support (28-57%). The most recent survey, in 2007, reported that 64% of respondents supported a change to presumed consent. Conclusion Presumed consent alone is unlikely to explain the variation in organ donation rates between countries

  15. 41 CFR 102-42.120 - When may gifts or decorations be donated to State agencies?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... PROPERTY 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts... may make the gifts or decorations available for donation to State agencies under this subpart and...

  16. 41 CFR 102-42.120 - When may gifts or decorations be donated to State agencies?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROPERTY 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts... may make the gifts or decorations available for donation to State agencies under this subpart and...

  17. 76 FR 7546 - Proposed Information Collection; Comment Request; Prohibited Species Donation (PSD) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ...; Prohibited Species Donation (PSD) Program AGENCY: National Oceanic and Atmospheric Administration (NOAA... currently approved information collection. A prohibited species donation (PSD) program for Pacific salmon.... Vessels and processing plants participating in the donation program voluntarily retain and process...

  18. 41 CFR 102-42.120 - When may gifts or decorations be donated to State agencies?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... PROPERTY 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts... may make the gifts or decorations available for donation to State agencies under this subpart and...

  19. DOE Fire Protection Handbook, Volume II. Fire effects and electrical and electronic equipment

    SciTech Connect

    1994-08-18

    Electrical and electronic equipment, including computers, are used at critical facilities throughout the Department of Energy (DOE). Hughes Associates, Inc. was tasked to evaluate the potential thermal and nonthermal effects of a fire on the electrical and electronic equipment and methods to analyze, evaluate, and assist in controlling the potential effects. This report is a result of a literature review and analysis on the effects of fire on electrical equipment. It is directed at three objectives: (1) Provide a state-of-the-art review and analysis of thermal and nonthermal damage to electrical and electronic equipment; (2) Develop a procedure for estimating thermal and nonthermal damage considerations using current knowledge; and (3) Develop an R&D/T&E program to fill gaps in the current knowledge needed to further perfect the procedure. The literature review was performed utilizing existing electronic databases. Sources searched included scientific and engineering databases including Dialog, NTIS, SciSearch and NIST BFRL literature. Incorporated in the analysis is unpublished literature and conversations with members of the ASTM E-5.21, Smoke Corrosivity, and researchers in the electronics field. This report does not consider the effects of fire suppression systems or efforts. Further analysis of the potential impact is required in the future.

  20. Protection of electrical and electronic equipment against lightning indirect effects on the Airbus A340 wing

    NASA Technical Reports Server (NTRS)

    Spiller, Olaf

    1991-01-01

    The provisions applied to the Airbus A340 wing wiring against lightning indirect effects are presented. The construction and installation of the wiring's shielding systems are described, and the analysis and tests performed to determine the effectiveness of the measures taken are discussed. A first evaluation of the results of the theoretical analysis together with the provisional results of tests indicate a sufficient safety margin between required and achieved protection levels.

  1. Social and ethical issues in mitochondrial donation

    PubMed Central

    Dimond, Rebecca

    2015-01-01

    Introduction or background The UK is at the forefront of mitochondrial science and is currently the only country in the world to legalize germ-line technologies involving mitochondrial donation. However, concerns have been raised about genetic modification and the ‘slippery slope’ to designer babies. Sources of data This review uses academic articles, newspaper reports and public documents. Areas of agreement Mitochondrial donation offers women with mitochondrial disease an opportunity to have healthy, genetically related children. Areas of controversy Key areas of disagreement include safety, the creation of three-parent babies, impact on identity, implications for society, definitions of genetic modification and reproductive choice. Growing points The UK government legalized the techniques in March 2015. Scientific and medical communities across the world followed the developments with interest. Areas timely for developing research It is expected that the first cohort of ‘three parent’ babies will be born in the UK in 2016. Their health and progress will be closely monitored. PMID:26351372

  2. Kidney paired donation: principles, protocols and programs.

    PubMed

    Ferrari, Paolo; Weimar, Willem; Johnson, Rachel J; Lim, Wai H; Tinckam, Kathryn J

    2015-08-01

    Due to the ongoing shortage of deceased-donor organs, novel strategies to augment kidney transplantation rates through expanded living donation strategies have become essential. These include desensitization in antibody-incompatible transplants and kidney paired donation (KPD) programs. KPD enables kidney transplant candidates with willing but incompatible living donors to join a registry of other incompatible pairs in order to find potentially compatible transplant solutions. Given the significant immunologic barriers with fewer donor options, single-center or small KPD programs may be less successful in transplanting the more sensitized patients; the optimal solution for the difficult-to-match patient is access to more potential donors and large multicenter or national registries are essential. Multicenter KPD programs have become common in the last decade, and now represent one of the most promising opportunities to improve transplant rates. To maximize donor-recipient matching, and minimize immunologic risk, these multicenter KPD programs use sophisticated algorithms to identify optimal match potential, with simultaneous two-, three- or more complex multiway exchanges. The article focuses on the recent progresses in KPD and it also reviews some of the differences and commonalities across four different national KPD programs. PMID:25294848

  3. 32 CFR 644.495 - Donation to a public body.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Donation to a public body. 644.495 Section 644.495 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... Land) § 644.495 Donation to a public body. A public body, as defined by GSA for this purpose, means...

  4. 32 CFR 644.495 - Donation to a public body.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Donation to a public body. 644.495 Section 644.495 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... Land) § 644.495 Donation to a public body. A public body, as defined by GSA for this purpose, means...

  5. 32 CFR 644.494 - Donation, abandonment or destruction.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Donation, abandonment or destruction. 644.494 Section 644.494 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... Land) § 644.494 Donation, abandonment or destruction. (a) General. Improvements may be...

  6. 32 CFR 644.494 - Donation, abandonment or destruction.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Donation, abandonment or destruction. 644.494 Section 644.494 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... Land) § 644.494 Donation, abandonment or destruction. (a) General. Improvements may be...

  7. 32 CFR 644.495 - Donation to a public body.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Donation to a public body. 644.495 Section 644.495 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... Land) § 644.495 Donation to a public body. A public body, as defined by GSA for this purpose, means...

  8. 32 CFR 644.494 - Donation, abandonment or destruction.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Donation, abandonment or destruction. 644.494 Section 644.494 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... Land) § 644.494 Donation, abandonment or destruction. (a) General. Improvements may be...

  9. 38 CFR 60.3 - Other donated temporary lodging.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) FISHER HOUSES AND OTHER TEMPORARY LODGING § 60.3 Other donated temporary lodging. Whenever VA receives, from a source other than the Fisher House Foundation, an undesignated donation of lodging to be used on a temporary basis, the lodging will be designated as if it were Fisher House lodging or...

  10. 38 CFR 60.3 - Other donated temporary lodging.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) FISHER HOUSES AND OTHER TEMPORARY LODGING § 60.3 Other donated temporary lodging. Whenever VA receives, from a source other than the Fisher House Foundation, an undesignated donation of lodging to be used on a temporary basis, the lodging will be designated as if it were Fisher House lodging or...

  11. 78 FR 3023 - Draft Policy on Donations, Fundraising, and Solicitation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-15

    ... that we will post any personal information you provide us (see Request for Public Comments under..., including real and personal property, services, and money. These include the Fish and Wildlife Coordination... and personal property donations. Other authorities cited in this draft donations policy include...

  12. 32 CFR 644.495 - Donation to a public body.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Donation to a public body. 644.495 Section 644.495 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Buildings and Other Improvements (without the Related Land) § 644.495 Donation to a public body. A...

  13. Indian ICU nurses' perceptions of and attitudes towards organ donation.

    PubMed

    Vijayalakshmi, Poreddi; Nagarajaiah; Ramachandra; Math, Suresh Bada

    Nurses play a significant role in identifying and securing potential organ donors in the clinical environment. Research among Indian nurses related to organ donation is sparse. The present study aimed to investigate nurses' attitudes towards organ donation. A cross-sectional descriptive survey was carried out among nurses (n=184) at a tertiary care centre. Data were collected through self-report questionnaire. A majority (81%) of the respondents were 'willing to sign the card' for organ donation; however, only 3.8% (n=7) of them actually 'signed the organ donation card'. There were significant associations found between intentions to sign the organ donation card and gender (x2=5.852; p<0.054), religion (x2=40.175; p<0.000), and experience caring for brain-dead patients (x2=22.790; p<0.001). The researchers strongly suggest continuing education for nurses to enhance skills and knowledge, as well as sensitivity to cultural, ethical, social, and religious issues, and advocacy in the area of organ donation. Furthermore, nurse administrators must take the initiative to develop guidelines clarifying the role of nurses in the organ donation and transplantation process to promote organ donation and improve rates. PMID:26153809

  14. 77 FR 20495 - National Donate Life Month, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... Independence of the United States of America the two hundred and thirty-sixth. (Presidential Sig.) [FR Doc... Documents#0;#0; ] Proclamation 8792 of April 2, 2012 National Donate Life Month, 2012 By the President of... national character. During National Donate Life Month, we reflect on that essential quality and recommit...

  15. 75 FR 17843 - National Donate Life Month, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ... of America the two hundred and thirty-fourth. (Presidential Sig.) [FR Doc. 2010-8026 Filed 4-6-10; 8... Documents#0;#0; ] Proclamation 8491 of April 1, 2010 National Donate Life Month, 2010 By the President of.... During National Donate Life Month, we honor donors who provide others with a second chance for a...

  16. 78 FR 20217 - National Donate Life Month, 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ... hundred and thirty- seventh. (Presidential Sig.) [FR Doc. 2013-07921 Filed 4-3-13; 8:45 am] Billing code... Documents#0;#0; ] Proclamation 8950 of March 29, 2013 National Donate Life Month, 2013 By the President of... commitment to one another. During National Donate Life Month, we renew the call for organ and tissue...

  17. Using Standardized Patients to Educate Medical Students about Organ Donation

    ERIC Educational Resources Information Center

    Feeley, Thomas Hugh; Anker, Ashley E.; Soriano, Rainier; Friedman, Erica

    2010-01-01

    Medical students at Mount Sinai School of Medicine participated in an intervention designed to promote knowledge and improved communication skills related to cadaveric organ donation. The intervention required students to interact with a standardized patient for approximately 10 minutes and respond to questions posed about organ donation in a…

  18. 7 CFR 3015.53 - Valuation of donated services.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Valuation of donated services. 3015.53 Section 3015....53 Valuation of donated services. (a) Volunteer services. Unpaid services provided to a recipient by... labor market. In either case, a reasonable amount for fringe benefits may be included in the...

  19. 7 CFR 250.30 - State processing of donated foods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false State processing of donated foods. 250.30 Section 250.30 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION DONATION OF FOODS FOR USE IN THE UNITED STATES, ITS TERRITORIES...

  20. 7 CFR 250.30 - State processing of donated foods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false State processing of donated foods. 250.30 Section 250.30 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION DONATION OF FOODS FOR USE IN THE UNITED STATES, ITS TERRITORIES...

  1. Body Donation after Death: The Mental Setup of Educated People

    PubMed Central

    Sarkar, Aniruddha; Mandal, Shyamash

    2015-01-01

    Introduction Without dissection of cadavers teaching and learning of anatomy is nearly difficult; there remains a gap between the practical knowledge and the gathered theoretical knowledge. But there is a scarcity in the availability of the donated bodies for the sake of medical education. On the other hand a large number of people in our country are in waiting list for organ transplantation which could be overcome by deceased organ donation. Aim Aim of the study was to evaluate the awareness regarding body donation after death. Materials and Methods A cross-sectional study was conducted among medical students, engineering students and doctors in Indian population. Total 300 participants were answered the questionnaire providing information about the knowledge and attitude towards body and organ donation. Result 46.33% of entire study group had strongly positive attitude about cadaveric organ donation and 17% had no idea about this. 18% of total participants were unwilling for body donation after death. Conclusion The present study has been done elaborately to find out the different barriers for body or organ donation. It is clear from the study that though there is high level of awareness, nobody has filled up the pledge form till now. It indicates that there is a gap between the knowledge and motivation for organ and body donation after death which has to be overcome by proper guidance and education. Media and other voluntary organisations could take an important role for this purpose. PMID:26266106

  2. 7 CFR 226.5 - Donation of commodities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Donation of commodities. 226.5 Section 226.5... of commodities. (a) USDA foods available under section 6 of this Act, section 416 of the Agricultural... the Department shall be made available to each State. (b) The value of such commodities donated...

  3. Body Donation in India: Social Awareness, Willingness, and Associated Factors

    ERIC Educational Resources Information Center

    Rokade, Shrikant A.; Gaikawad, Anjana P.

    2012-01-01

    With the attendant rise of the number of medical colleges in India over past few decades, the demand for cadavers used in medical education and research is growing. However, there is an insufficient supply of donated cadavers available for dissection. This study was undertaken to assess the general population's awareness of body donation programs…

  4. 32 CFR 644.494 - Donation, abandonment or destruction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Donation, abandonment or destruction. 644.494 Section 644.494 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE HANDBOOK Disposal Disposal of Buildings and Other Improvements (without the Related Land) § 644.494 Donation, abandonment...

  5. Voluntary Body Donation: The Gift that Lives on Forever

    NASA Astrophysics Data System (ADS)

    Saritha, S.; Rao, M. Vittoo; Sumangala; Supriya, G.; Kumar, Praveen

    2012-10-01

    Body donation is a gracious act, Shankarcharaya firmly believed in concept of Body Donation or Organ Donation and said Iddham sharirum paropakarum i.e. the body is for use of others and death is not the end, it is the beginning. Anatomy is important basic subject for medicalstudents, both U.G. & P.G. Best method of Anatomy learning is by dissection on human cadavers, which remains principle teaching tool. Human cadavers for purpose of study are a scarcity with mushrooming of medical institutions in this country. Unclaimed bodies are no more origin of cadavers. Whole Body donation is the need of the hour. A Voluntary Body Donation is defined as the act of giving oneís Body after death for Medical research and education. In this article a survey was done in S.V.S. Medical & Dental Colleges Faculty members and medical exhibition visitors which include lawyers, engineers, teachers and others during the year of 2010. The body donation including organ donation and various factors such as age, religion, culture and donorís attitude are discussed. Body donation provides the students and medical researchers with unparalleled opportunities to study the human body. Computers nor books cannot totally replace body dissection in learning the anatomy.

  6. Characterizing donation behavior from psychophysiological indices of narrative experience

    PubMed Central

    Correa, Kelly A.; Stone, Bradly T.; Stikic, Maja; Johnson, Robin R.; Berka, Chris

    2015-01-01

    Research on narrative persuasion has yet to investigate whether this process influences behavior. The current study explored whether: (1) a narrative could persuade participants to donate to a charity, a prosocial, behavioral decision; (2) psychophysiological metrics can delineate the differences between donation/non-donation behaviors; and (3) donation behavior can be correlated with measures of psychophysiology, self-reported reactions to the narrative, and intrinsic characteristics. Participants (n = 49) completed personality/disposition questionnaires, viewed one of two versions of a narrative while EEG and ECG were recorded, completed a questionnaire regarding their reactions to the narrative, and were given an opportunity to donate to a charity related to the themes of the narrative. Results showed that: (1) 34.7% of participants donated; (2) psychophysiological metrics successfully delineated between donation behaviors and the effects of narrative version; and (3) psychophysiology and reactions to the narrative were better able to explain the variance (88 and 65%, respectively) in the amount donated than all 3 metrics combined as well as any metric alone. These findings demonstrate the promise of narrative persuasion for influencing prosocial, behavioral decisions. Our results also illustrate the utility of the previously stated metrics for understanding and possibly even manipulating behaviors resulting from narrative persuasion. PMID:26379488

  7. Spirituality and post-graduate students' attitudes towards blood donation.

    PubMed

    Almeida, Rodrigo G S; Martinez, Edson Z; Mazzo, Alessandra; Trevizan, Maria A; Mendes, Isabel A C

    2013-06-01

    College students have become more representative as blood donors, mainly to help other people. This study ascertained the association between spirituality and adherence or intention to donate blood in post-graduate students. In this quantitative and cross-sectional study, participants were 281 students from a post-graduate programme at a Brazilian public university. After complying with ethical requirements, data were collected through a questionnaire for sociodemographic characterization and identification of blood donation practices, followed by the Spiritual Well-Being Scale. Descriptive statistics and parametric tests were used for data analysis. A total of 74% of the participants were female and 26% were male. Previous experience and/or intention to donate blood were found in 75.3%; 14.3% donated blood periodically. In addition, 12.2% were not adept to donation and 12.5% were inapt. Spiritual Well-Being scores were similar between individuals who are not adept and those who donate periodically. In conclusion, in the sample, spirituality and blood donation are not associated, but spiritual well-being and gender are. To enhance blood donation, further research is needed. PMID:23361148

  8. An Empirical Exploration of Selected Policy Options in Organ Donation.

    ERIC Educational Resources Information Center

    Klenow, Daniel J.; Youngs, George A., Jr.

    1995-01-01

    Presents findings from a mail survey of 414 persons regarding organ transplantation and donation policy issues. Gauged three measures of support for organ donation: donor card commitment, required request of next-of-kin support, and weak presumed consent support. High levels of support exist for organ donor cards and the next-of-kin law. Little…

  9. 75 FR 16676 - Airworthiness Standards; Electrical and Electronic System Lightning Protection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... Issues (57 FR 58843; December 11, 1992) to develop recommendations for specific electrical and electronic... published on April 11, 2000 (65 FR 19477-78) or you may visit http://DocketsInfo.dot.gov . Docket: To read... systems on part 25 transport category airplanes. The final rule was published on April 28, 1994 (59...

  10. Using electronic wristbands and a triage protocol to protect mental health patients in the emergency department.

    PubMed

    Macy, Deborah; Johnston, Michelle

    2007-01-01

    In the emergency department of Mercy Hospital, concerns about possible elopement of mental health patients led to the use of the services of security officers, who were called for an average of 40 patient watches per week. Modified electronic wristbands, paired with a triage protocol, have significantly decreased the need for patient watches and decreased security costs. PMID:17353756

  11. Medical Students' Knowledge, Familiarity, and Attitudes towards Hematopoietic Stem Cell Donation: Stem Cell Donation Behaviors.

    PubMed

    Narayanan, Praveena; Wolanskyj, Alexandra; Ehlers, Shawna L; Litzow, Mark R; Patnaik, Mrinal S; Hogan, William J; Hashmi, Shahrukh K

    2016-09-01

    Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for patients with blood disorders and genetic diseases. Approximately 70% of the HSCTs currently performed in the United States use stems cells from an unrelated donor who donated voluntarily. Medical students (MS) are a young, diverse, influential population whose willingness to engage in altruistic acts, such as donating stem cells, may be correlated with knowledge on the topic. A literature gap exists in MS perspectives towards HSCT and the bone marrow registry (BMR) and prior studies suggest that misconceptions about donation deter MS from participation on the BMR, which may decrease opportunities to educate other potential donors. We performed a cross-sectional survey among the 4-year cohort of MS at Mayo Medical School in Rochester, Minnesota. The questionnaire evaluated multiple areas including whether MS were current members of the BMR and/or prior blood donors, MS current knowledge on donor eligibility (DE) and the donation process (DP), MS familiarity with HSCT and the DP, and MS attitudes towards joining the BMR and towards donating stem cells. The responses were analyzed and assessed alongside a self-reported, standardized scale measuring students' altruistic behaviors. There were 99 out of 247 potential respondents (40%), with 45% (n = 44) of MS in preclinical years 1 or 2, 37% (n = 37) in clinical years 3 or 4, and 18% (n = 18) in research or alternative portions of their training, of which 43% (n = 41) in total were current BMR members. BMR status correlated positively with prior blood donation (P = .015) and female sex (P = .014). Respondents had a 57.7% and 63.7% average correct response rate regarding knowledge of DE and DP, respectively, with knowledge of DE not surprisingly higher in BMR members (P < .0001). The majority of MS surveyed, 68% (n = 65), had learned about HSCT during medical school. BMR status correlated with the

  12. Electronic and geometric structures of Au30 clusters: a network of 2e-superatom Au cores protected by tridentate protecting motifs with u3-S

    NASA Astrophysics Data System (ADS)

    Tian, Zhimei; Cheng, Longjiu

    2015-12-01

    2(SR)18 clusters are Au17, Au20 and Au14, respectively. The superatom-network (SAN) model and the superatom complex (SAC) model are used to explain the chemical bonding patterns, which are verified by chemical bonding analysis based on the adaptive natural density partitioning (AdNDP) method and aromatic analysis on the basis of the nucleus-independent chemical shift (NICS) method. The Au17 core of the Au30S(SR)18 cluster can be viewed as a SAN of one Au6 superatom and four Au4 superatoms. The shape of the Au6 core is identical to that revealed in the recently synthesized Au18(SR)14 cluster. The Au20 core of the Au30(SR)18 cluster can be viewed as a SAN of two Au6 superatoms and four Au4 superatoms. The Au14 core of Au30S2(SR)18 can be regarded as a SAN of two pairs of two vertex-sharing Au4 superatoms. Meanwhile, the Au14 core is an 8e-superatom with 1S21P6 configuration. Our work may aid understanding and give new insights into the chemical synthesis of thiolate-protected Au clusters. Electronic supplementary information (ESI) available: The AdNDP localized natural bonding orbitals of the valence shells of the Au30S(SH)18 cluster. IR spectra, absorption spectra and coordinates of Au30S(SCH3)18, Au30(SCH3)18 and Au30S2(SCH3)18 clusters. See DOI: 10.1039/c5nr05020k

  13. Suppression of the antiferromagnetic pseudogap in the electron-doped high-temperature superconductor by protect annealing

    PubMed Central

    Horio, M.; Adachi, T.; Mori, Y.; Takahashi, A.; Yoshida, T.; Suzuki, H.; Ambolode, L. C. C.; Okazaki, K.; Ono, K.; Kumigashira, H.; Anzai, H.; Arita, M.; Namatame, H.; Taniguchi, M.; Ootsuki, D.; Sawada, K.; Takahashi, M.; Mizokawa, T.; Koike, Y.; Fujimori, A.

    2016-01-01

    In the hole-doped cuprates, a small number of carriers suppresses antiferromagnetism and induces superconductivity. In the electron-doped cuprates, on the other hand, superconductivity appears only in a narrow window of high-doped Ce concentration after reduction annealing, and strong antiferromagnetic correlation persists in the superconducting phase. Recently, Pr1.3−xLa0.7CexCuO4 (PLCCO) bulk single crystals annealed by a protect annealing method showed a high critical temperature of around 27 K for small Ce content down to 0.05. Here, by angle-resolved photoemission spectroscopy measurements of PLCCO crystals, we observed a sharp quasi-particle peak on the entire Fermi surface without signature of an antiferromagnetic pseudogap unlike all the previous work, indicating a dramatic reduction of antiferromagnetic correlation length and/or of magnetic moments. The superconducting state was found to extend over a wide electron concentration range. The present results fundamentally challenge the long-standing picture on the electronic structure in the electron-doped regime. PMID:26843063

  14. Suppression of the antiferromagnetic pseudogap in the electron-doped high-temperature superconductor by protect annealing.

    PubMed

    Horio, M; Adachi, T; Mori, Y; Takahashi, A; Yoshida, T; Suzuki, H; Ambolode, L C C; Okazaki, K; Ono, K; Kumigashira, H; Anzai, H; Arita, M; Namatame, H; Taniguchi, M; Ootsuki, D; Sawada, K; Takahashi, M; Mizokawa, T; Koike, Y; Fujimori, A

    2016-01-01

    In the hole-doped cuprates, a small number of carriers suppresses antiferromagnetism and induces superconductivity. In the electron-doped cuprates, on the other hand, superconductivity appears only in a narrow window of high-doped Ce concentration after reduction annealing, and strong antiferromagnetic correlation persists in the superconducting phase. Recently, Pr1.3-xLa0.7CexCuO4 (PLCCO) bulk single crystals annealed by a protect annealing method showed a high critical temperature of around 27 K for small Ce content down to 0.05. Here, by angle-resolved photoemission spectroscopy measurements of PLCCO crystals, we observed a sharp quasi-particle peak on the entire Fermi surface without signature of an antiferromagnetic pseudogap unlike all the previous work, indicating a dramatic reduction of antiferromagnetic correlation length and/or of magnetic moments. The superconducting state was found to extend over a wide electron concentration range. The present results fundamentally challenge the long-standing picture on the electronic structure in the electron-doped regime. PMID:26843063

  15. On the impacts of traditional Chinese culture on organ donation.

    PubMed

    Cai, Yu

    2013-04-01

    This article examines the impact of traditional Chinese culture on organ donation from the perspective of Confucianism, Buddhism, and Taoism. In each of these cultural systems, it appears that there are some particular sayings or remarks that are often taken in modern Chinese society to be contrary to organ donation, especially cadaveric organ donation. However, this article argues that the central concerns of Buddhism, Confucianism, and Taoism are "great love," "ren," and "dao," which can be reasonably interpreted to support organ donation. The author understands that each cultural system, in order to play its cultural function, must have its central concerns as well as relevant ritual practices (li) that incarnate its religious and ethical commitments. That is, each plays a general cultural role, which influences organ donation in particular not merely through abstract or general ethical principles and teachings, but through a combination of ethical teachings and the forming of particular ritual practices. This article contends that the primary reason Chinese individuals fail to donate sufficient cadaveric organs for transplantation is not because particular remarks or sayings from each of these systems appear to conflict with donation. Neither is it that the central concerns of these systems cannot support cadaveric donation. Rather, it is that modern Chinese individuals have failed to develop and secure relevant ritual practices that support the central concerns of organ transplantation. The article concludes that in order to promote more donations, there is a need to form relevant ritual practices supporting organ donation in conformity with the central concerns of these cultural systems. PMID:23449366

  16. Financial, vocational, and interpersonal impact of living liver donation.

    PubMed

    Holtzman, Susan; Adcock, Lesley; Dubay, Derek A; Therapondos, George; Kashfi, Arash; Greenwood, Sarah; Renner, Eberhard L; Grant, David R; Levy, Gary A; Abbey, Susan E

    2009-11-01

    The ability to inform prospective donors of the psychosocial risks of living liver donation is currently limited by the scant empirical literature. The present study was designed to examine donor perceptions of the impact of donation on financial, vocational, and interpersonal life domains and identify demographic and clinical factors related to longer recovery times and greater life interference. A total of 143 donors completed a retrospective questionnaire that included a standardized measure of life interference [Illness Intrusiveness Rating Scale (IIRS)] and additional questions regarding the perceived impact of donation. Donor IIRS scores suggested that donors experience a relatively low level of life interference due to donation [1.60 +/- 0.72, with a possible range of 1 ("not very much" interference) to 7 ("very much" interference)]. However, approximately 1 in 5 donors reported that donating was a significant financial burden. Logistic regression analysis revealed that donors with a psychiatric diagnosis at or prior to donation took longer to return to their self-reported predonation level of functioning (odds ratio = 3.78, P = 0.016). Medical complications were unrelated to self-reported recovery time. Multiple regression analysis revealed 4 independent predictors of greater life interference: less time since donation (b = 0.11, P < 0.001), income lower than CAD$100,000 (b = 0.28, P = 0.038), predonation concerns about the donation process (b = 0.24, P = 0.008), and the perception that the recipient is not caring for the new liver (b = 0.12, P = 0.031). In conclusion, life interference due to living liver donation appears to be relatively low. Donors should be made aware of risk factors for greater life disruptions post-surgery and of the potential financial burden of donation. PMID:19877218

  17. Effect of population aging on the international organ donation rates and the effectiveness of the donation process.

    PubMed

    Cuende, N; Cuende, J I; Fajardo, J; Huet, J; Alonso, M

    2007-06-01

    This study analyzed the effect of population aging on organ donation for transplants in 43 countries and on the effectiveness of the donation process by comparing the results between Spain and the United States. The percentage of the population aged 65 or over accounted for 33% of the difference in the donation rates between the countries and for 91% of the variation in the rates after age adjustment. However, the level of aging of the Spanish (16.5%) and American (12.3%) populations failed to account for the percentages of deceased donors 65 or over (28% vs. 10%), due to the different age-specific donation rates, much higher in Spain above 50 years. These differences lead to a higher effectiveness of the process in the United States (3.1 transplanted organs per donor vs. 2.5 in Spain), though at lower rates of transplant per million population (73 vs. 87). We conclude that older populations have a greater donation potential as donation rates are strongly associated with population aging. It should therefore be mandatory to adjust donation rates for age before making comparisons. Additionally, effectiveness decreases with older donors, so age should be considered when establishing standards relating to organ donation and effectiveness of the process. PMID:17430401

  18. A Confirmatory Analysis of the Organ Donation Readiness Index: Measuring the Potential for Organ Donations among African Americans

    ERIC Educational Resources Information Center

    Rice, Christopher; Tamburlin, Judith

    2004-01-01

    The need for transplant exceeds the number of available organs. Antigen compatible organs are particularly scarce for African Americans because of their proportionately lower rate of donations. This study presents a measure of organ donation readiness. Examination of the factor structure and a test of weak invariance were conducted on…

  19. Operational Radiation Protection in Synchrotron Light and Free Electron Laser Facilities

    SciTech Connect

    Liu, James C.; Rokni, Sayed H.; Vylet, Vaclav; /Jefferson Lab

    2009-12-11

    The 3rd generation synchrotron radiation (SR) facilities are storage ring based facilities with many insertion devices and photon beamlines, and have low injection beam power (< few tens of watts), but extremely high stored beam power ({approx} 1 GW). The 4th generation x-ray free electron laser (FEL) facilities are based on an electron Linac with a long undulator and have high injection beam power (a few kW). Due to its electron and photon beam characteristics and modes of operation, storage ring and photon beamlines have unique safety aspects, which are the main subjects of this paper. The shielding design limits, operational modes, and beam losses are first reviewed. Shielding analysis (source terms and methodologies) and interlocked safety systems for storage ring and photon beamlines (including SR and gas bremsstrahlung) are described. Specific safety issues for storage ring top-off injection operation and FEL facilities are discussed. The operational safety program, e.g., operation authorization, commissioning, training, and radiation measurements, for SR facilities is also presented.

  20. Overcoming beneficiary race as an impediment to charitable donations: social dominance orientation, the experience of moral elevation, and donation behavior.

    PubMed

    Freeman, Dan; Aquino, Karl; McFerran, Brent

    2009-01-01

    Three studies examined the relationship between social dominance orientation (SDO), the experience of moral elevation, and Whites' donations to charitable organizations. Study 1 used video clips depicting acts of moral excellence to elicit a state of moral elevation (a distinctive feeling of warmth and expansion, which is accompanied by admiration, affection, and even love for people whose exemplary moral behavior is being observed). Results show that moral elevation increased participants' willingness to donate to a Black-oriented charity and attenuated the negative effect of the group-based dominance (GBD) component of SDO on donation behavior. Studies 2 and 3 replicate and extend these findings by using a written story to elicit a state of moral elevation and examining actual donations to a Black-oriented charity. Results show that moral elevation increased donations to the Black-oriented charity and neutralized the negative influence of GBD. PMID:19017786

  1. Improvements for international medicine donations: a review of the World Health Organization Guidelines for Medicine Donations, 3rd edition.

    PubMed

    Cañigueral-Vila, Nuria; Chen, Jennifer C; Frenkel-Rorden, Lindsey; Laing, Richard

    2015-01-01

    Some humanitarian and development organizations respond to major natural disasters and emergencies by donating medicines. Many provide medicines on a routine basis to support health systems, particularly those run by Faith-Based Organizations. Although such donations can provide essential medicines to populations in great need, inappropriate donations also take place, with burdensome consequences. The World Health Organization (WHO) has developed the interagency Guidelines for Medicine Donations for use by donors and recipients in the context of emergency aid and international development assistance. Although comprehensive in nature and transferable to various emergency situations, adjustments to both content and formatting would improve this resource. Recommendations for the next version of these guidelines include: specific wording and consistent formatting; definition of who is a recipient, clear distinction between acute and long-term emergencies, and proper donation procedures pertaining to each; inclusion of visual aides such as flowcharts, checklists, and photos; and improving the citations system. PMID:26525948

  2. Vacuum ultra-violet emission of plasma discharges with high Xe partial pressure using a cathode protective layer with high secondary electron emission

    SciTech Connect

    Zhu, Di; Song, Le; Zhang, Xiong; Kajiyama, Hiroshi

    2014-02-14

    In this work, the mechanism of the vacuum ultra-violet (VUV) emission of plasma discharges, with high Xe partial pressure and high ion-induced secondary electrons emission protective layer, is studied by measuring the VUV light emission directly and comparing it with two-dimensional simulations. From the panel measurement, we find that the high intensity of excimer VUV mainly contributes to the high luminous efficacy of SrCaO-plasma display panels (PDP) at a low sustain voltage. The unchanged Xe excitation efficiency indicates that the electron temperature is not decreased by the high secondary electrons emission protective layer, even though the sustain voltage is much lower. From the two-dimensional simulations, we can find that the ratio of excimer VUV to resonant VUV, which is determined by the collision rate in the discharge, is only significantly affected by the Xe partial pressure, while it is independent of the sustain voltage and the secondary-electrons-emission capability of protective layer. The unchanged average electron energy at the moment when the electric field becomes maximum confirms that the improvement of the VUV production efficiency mainly is attributed to the increase in electron heating efficiency of a PDP with high ion-induced secondary electrons emission protective layer. Combining the experimental and the simulation results, we conclude about the mechanism by which the VUV production is improved for the plasma display panel with a high Xe partial pressure and a cold cathode with high ion-induced secondary electrons emission.

  3. Living-Donor Kidney Transplantation: Reducing Financial Barriers to Live Kidney Donation--Recommendations from a Consensus Conference.

    PubMed

    Tushla, Lara; Rudow, Dianne LaPointe; Milton, Jennifer; Rodrigue, James R; Schold, Jesse D; Hays, Rebecca

    2015-09-01

    Live-donor kidney transplantation (LDKT) is the best treatment for eligible people with late-stage kidney disease. Despite this, living kidney donation rates have declined in the United States in recent years. A potential source of this decline is the financial impact on potential and actual living kidney donors (LKDs). Recent evidence indicates that the economic climate may be associated with the decline in LDKT and that there are nontrivial financial ramifications for some LKDs. In June 2014, the American Society of Transplantation's Live Donor Community of Practice convened a Consensus Conference on Best Practices in Live Kidney Donation. The conference included transplant professionals, patients, and other key stakeholders (with the financial support of 10 other organizations) and sought to identify best practices, knowledge gaps, and opportunities pertaining to living kidney donation. This workgroup was tasked with exploring systemic and financial barriers to living kidney donation. The workgroup reviewed literature that assessed the financial effect of living kidney donation, analyzed employment and insurance factors, discussed international models for addressing direct and indirect costs faced by LKDs, and summarized current available resources. The workgroup developed the following series of recommendations to reduce financial and systemic barriers and achieve financial neutrality for LKDs: (1) allocate resources for standardized reimbursement of LKDs' lost wages and incidental costs; (2) pass legislation to offer employment and insurability protections to LKDs; (3) create an LKD financial toolkit to provide standardized, vetted education to donors and providers about options to maximize donor coverage and minimize financial effect within the current climate; and (4) promote further research to identify systemic barriers to living donation and LDKT to ensure the creation of mitigation strategies. PMID:26002904

  4. Gay and Bisexual Men's Perceptions of the Donation and Use of Human Biological Samples for Research: A Qualitative Study.

    PubMed

    Patterson, Chris; McDaid, Lisa M; Hilton, Shona

    2015-01-01

    Human biological samples (biosamples) are increasingly important in diagnosing, treating and measuring the prevalence of illnesses. For the gay and bisexual population, biosample research is particularly important for measuring the prevalence of human immunodeficiency virus (HIV). By determining people's understandings of, and attitudes towards, the donation and use of biosamples, researchers can design studies to maximise acceptability and participation. In this study we examine gay and bisexual men's attitudes towards donating biosamples for HIV research. Semi-structured telephone interviews were conducted with 46 gay and bisexual men aged between 18 and 63 recruited in commercial gay scene venues in two Scottish cities. Interview transcripts were analysed thematically using the framework approach. Most men interviewed seemed to have given little prior consideration to the issues. Participants were largely supportive of donating tissue for medical research purposes, and often favourable towards samples being stored, reused and shared. Support was often conditional, with common concerns related to: informed consent; the protection of anonymity and confidentiality; the right to withdraw from research; and ownership of samples. Many participants were in favour of the storage and reuse of samples, but expressed concerns related to data security and potential misuse of samples, particularly by commercial organisations. The sensitivity of tissue collection varied between tissue types and collection contexts. Blood, urine, semen and bowel tissue were commonly identified as sensitive, and donating saliva and as unlikely to cause discomfort. To our knowledge, this is the first in-depth study of gay and bisexual men's attitudes towards donating biosamples for HIV research. While most men in this study were supportive of donating tissue for research, some clear areas of concern were identified. We suggest that these minority concerns should be accounted for to develop

  5. Semiclassical electron transport at the edge of a two-dimensional topological insulator: Interplay of protected and unprotected modes

    NASA Astrophysics Data System (ADS)

    Khalaf, E.; Skvortsov, M. A.; Ostrovsky, P. M.

    2016-03-01

    We study electron transport at the edge of a generic disordered two-dimensional topological insulator, where some channels are topologically protected from backscattering. Assuming the total number of channels is large, we consider the edge as a quasi-one-dimensional quantum wire and describe it in terms of a nonlinear sigma model with a topological term. Neglecting localization effects, we calculate the average distribution function of transmission probabilities as a function of the sample length. We mainly focus on the two experimentally relevant cases: a junction between two quantum Hall (QH) states with different filling factors (unitary class) and a relatively thick quantum well exhibiting quantum spin Hall (QSH) effect (symplectic class). In a QH sample, the presence of topologically protected modes leads to a strong suppression of diffusion in the other channels already at scales much shorter than the localization length. On the semiclassical level, this is accompanied by the formation of a gap in the spectrum of transmission probabilities close to unit transmission, thereby suppressing shot noise and conductance fluctuations. In the case of a QSH system, there is at most one topologically protected edge channel leading to weaker transport effects. In order to describe `topological' suppression of nearly perfect transparencies, we develop an exact mapping of the semiclassical limit of the one-dimensional sigma model onto a zero-dimensional sigma model of a different symmetry class, allowing us to identify the distribution of transmission probabilities with the average spectral density of a certain random-matrix ensemble. We extend our results to other symmetry classes with topologically protected edges in two dimensions.

  6. [The prevention of noise inducted hearing loss: the new challenge of active electronic hearing protection].

    PubMed

    Giordano, Carlo; Cociglio, Marco; Nadalin, Juri; Bronuzzi, Fabrizio; Raimondo, Luca; Riva, Giuseppe; Pira, Enrico; Coggiola, Maurizio; Victorians, Tom

    2011-01-01

    Based on today's common hearing aid design and technology, the team of researchers successfully designed a DPI which allows the worker to be "protected" against loudness and in the same time guarantee a good level of communication and perception of the surrounding environment. The design of this new device is very much similar to a standard BTE hearing aid which allows the use of an active DPI very comfortable, robust and easy to use. The research using the prototypes was divided into 3 phases: Phase 1: 24 volunteers coming from non-industry companies did undergo a specific trial protocol. Phase 2: 6 workers coming from a mining company did undergo the same protocol used in Phase 1. Phase 3: The Acoustics Laboratory from the "Energetica" Department of the Polytechnic of Turin (University/Institute) took objective measures for the DPI attenuation figures used in phase 1 and 2. PMID:22073685

  7. Legislating organ donation: problems with this approach.

    PubMed

    Sutherland, F R

    1997-02-01

    The number of organs available for transplantation in Canada is insufficient to meet the demand, so many patients die waiting for surgery. Improving the supply of donor organs by enacting legislation is controversial. Three approaches to legislation have been suggested: required request, mandated choice, and presumed consent. Required-request legislation demands that physicians ask all families of potential donors for permission to retrieve organs. Mandated choice requires all adults to register whether they wish to be organ donors. Presumed consent allows the removal of organs without permission if no choice was registered. These laws are aimed at coercion of physicians, patients and families retrospectively, but their relative success and ethics are questionable. Facilitating the organ donation process may be a better solution. PMID:12380582

  8. Family discussions about organ donation: how the media influences opinions about donation decisions.

    PubMed

    Morgan, Susan E; Harrison, Tyler R; Long, Shawn D; Afifi, Walid A; Stephenson, Michael T; Stephenson, Michael S; Reichert, Tom

    2005-10-01

    In this study, 78 family pair dyads (spouses, parent-child pairs, or siblings) were brought into an interaction laboratory set up like a living room. After being briefed on the study, family members discussed a series of eight questions about their thoughts and opinions about organ donation. Thematic analysis of the thousands of pages of transcripts revealed that family members believe that they receive important information about organ donation through the media. Unfortunately, the most influential information came from sensationalistic, negative media portrayals. The myths that seem to be the most actively referenced by the media include premature declaration of death, the transference of personality traits from donor to recipient, a US black market for organs, corruption in the medical community, and corruption in the organ allocation system (which allows celebrities to get transplants first). Although these are not the only myths that the generally public holds to be true, the media is a powerful source of support for these particular myths. Therefore, such myths must be countered effectively if greater consent for organ donation is to be attained. PMID:16146561

  9. Effects of cadmium on the activities of photosystems of Chlorella pyrenoidosa and the protective role of cyclic electron flow.

    PubMed

    Wang, Shuzhi; Zhang, Daoyong; Pan, Xiangliang

    2013-09-01

    Cadmium (Cd) shows high toxicity to aquatic microalgae. Many studies showed that Cd inhibited activities of photosystem II (PSII) but the effects of heavy metals on photosystem I (PSI) and cyclic electron flow (CEF) were still controversial and unclear. The effects of CdCl2 on the activities of PSI, PSII and CEF in Chlorella pyrenoidosa was measured simultaneously in the present study. In presence of 200μM of Cd, ultrastructure of some cells was strongly modified. Cd exposure led to decrease of the activities of photosynthetic oxygen evolution and respiration. PSII was more sensitive to Cd treatment than PSI. Cd treatment showed significant inhibition on the photochemical quantum yield and electron transport rate of PSII. Cd increased the quantum yield of non-light-induced non-photochemical fluorescence quenching, indicating the damage of PSII. The activity of PSI showed tolerance to Cd treatment with concentration less than 100μM in the experiment. Linear electron flow (LEF) made significant contribution to the photochemical quantum yield of PSI of the untreated cells, but decreased with increasing Cd concentration. The contribution of CEF to the yield of PSI increased with increasing Cd concentration. The activation of CEF after exposure to Cd played an essential role for the protection of PSI. PMID:23726885

  10. Umbilical cord blood donation: public or private?

    PubMed

    Ballen, K K; Verter, F; Kurtzberg, J

    2015-10-01

    Umbilical cord blood (UCB) is a graft source for patients with malignant or genetic diseases who can be cured by allogeneic hematopoietic cell transplantation (HCT), but who do not have an appropriately HLA-matched family or volunteer unrelated adult donor. Starting in the 1990s, unrelated UCB banks were established, accepting donations from term deliveries and storing UCB units for public use. An estimated 730 000 UCB units have been donated and stored to date and ~35 000 UCB transplants have been performed worldwide. Over the past 20 years, private and family banks have grown rapidly, storing ~4 million UCB units for a particular patient or family, usually charging an up-front and yearly storage fee; therefore, these banks are able to be financially sustainable without releasing UCB units. Private banks are not obligated to fulfill the same regulatory requirements of the public banks. The public banks have released ~30 times more UCB units for therapy. Some countries have transitioned to an integrated banking model, a hybrid of public and family banking. Today, pregnant women, their families, obstetrical providers and pediatricians are faced with multiple choices about the disposition of their newborn's cord blood. In this commentary, we review the progress of UCB banking technology; we also analyze the current data on pediatric and adult unrelated UCB, including the recent expansion of interest in transplantation for hemoglobinopathies, and discuss emerging studies on the use of autologous UCB for neurologic diseases and regenerative medicine. We will review worldwide approaches to UCB banking, ethical considerations, criteria for public and family banking, integrated banking ideas and future strategies for UCB banking. PMID:26030051

  11. Jewish medical ethics: monetary compensation for donating kidneys.

    PubMed

    Grazi, Richard V; Wolowelsky, Joel B

    2004-03-01

    The Israel Health Ministry is preparing legislation that would allow a person to receive monetary compensation in exchange for donating a kidney for a lifesaving transplant. Such a bill would be the first of its kind, and would seem to establish a policy that is in contrast with both existing international professional ethics and major Christian and Islamic religious ethics. In an attempt to investigate the extent to which such a bill would be consistent with traditional Jewish ethics, we reviewed the opinions of major traditional Jewish ethicists/halakhists, with emphasis on contemporary opinions, and found that compensating an organ donor for his or her time, discomfort, inconvenience, and recovery is fully consistent with traditional Jewish law and ethics. While non-altruistic sale of kidneys might be theoretically ethical from a Jewish perspective, ultimately its ethical status is inextricably connected to solving a series of pragmatic issues, such as creating a system that insures that potential vendors/donors are properly informed and not exploited, controlling and supervising medical screening and support of the donors to insure that their health is not permanently endangered, protecting minors and incompetents, and regulating payments so that they reasonably reflect compensation for pain and suffering. PMID:15055281

  12. Barriers to organ donation in the Jewish community.

    PubMed

    Feld, J; Sherbin, P; Cole, E

    1998-03-01

    It has long been recognized that members of the Jewish community generally do not sign organ donor cards or consent to the donation of the organs of their family members. In order to address this issue, the position of Jewish law on organ donation was examined and a sample of the Jewish population of Toronto was surveyed in an attempt to better understand the reasons for the observed reluctance to donate within this community. The results confirmed that the rate of signing organ donor cards was much lower in the Jewish community than in the general population, and although other reasons do exist, the major barrier to donation was a perception that Jewish law prohibits such action. The study of Jewish law revealed that organ donation is permitted and, in fact, encouraged by all branches of modern Judaism. Finally, in response to these results, a guide titled "Organ Donation: A Jewish Perspective" was compiled to help explain both the religious and medical aspects of organ donation for Jewish people and transplant personnel. PMID:9726215

  13. National Adult Protective Services Association

    MedlinePlus

    ... and administrators, professionals in the aging and disabilities networks, students in social service programs, or anyone committed to protecting our most vulnerable citizens. NAPSA will connect you with peers throughout the country, provide the most ... Our supporters have become part of a network whose valuable donations of time and money are ...

  14. Sperm donation and its application in China: a 7-year multicenter retrospective study

    PubMed Central

    Ping, Ping; Zhu, Wen-Bing; Zhang, Xin-Zong; Li, Yu-Shan; Wang, Quan-Xian; Cao, Xiao-Rong; Liu, Yong; Dai, Hui-Li; Huang, Yi-Ran; Li, Zheng

    2011-01-01

    Sperm donation in China is different from that in other countries due to cultural, social and political factors. This research presents the current status of sperm donation in Mainland China and highlights some problems. Between January 2003 and December 2009, 19 471 sperm donors were screened totally and 6467 donors (33.2%) were recruited. The primary reasons for non-recruitment were either inadequate semen parameters (55.0%) or positive results for sexually transmitted diseases (7.9%). There were 327 (1.7%) qualified donors who withdrew from the program because of frustration related to failed semen parameters, participation merely for free medical tests or job transfer. A questionnaire investigating donor intention, as well as other concerns associated with sperm donation, was distributed to 516 potential donors. All potential donors indicated their primary motivation as altruism, while 90.9% mentioned monetary reward as a second motivating factor. Approximately 93.4% of donors expressed some apprehension about the risk of consanguineous mating and the protection of their identity. Over the past 7 years, 488 389 vials of donors' semen have been cryopreserved. In 36 438 artificial insemination with donor sperm (AID) cycles, the clinical pregnancy rate was 23.9% and the live birth rate was 16.6%. In 7148 in vitro fertilization cycles, the clinical pregnancy rate was 45.8% and the live birth rate was 35.2%. Human sperm banks have been strictly monitored to ensure that each sperm donor can only impregnate five women nationwide. There is still a large gap between the supply and demand for sperm donation which may be solved by updated guidelines. PMID:21623386

  15. Organ Donation Decision: Comparison of Donor and Nondonor Families

    PubMed Central

    Rodrigue, J. R.; Cornell, D. L.; Howard, R. J.

    2008-01-01

    Family members continue to play a prominent role in donation decisions at time of death. This study examined the relative influence of donor and next-of-kin factors, requestor characteristics, communication processes and satisfaction with the health care team on the donation decision. Data were gathered via structured telephone interview with 285 next-of-kin of donor-eligible deceased individuals who had been approached by coordinators from one organ procurement organization (OPO) in the southeastern USA from July 2001 to February 2004. Univariate and multivariate analyses showed that several variables were associated with the donation decision. Subsequent logistic regression analyses revealed that donation was more likely when the deceased was younger, white (OR = 3.20, CI = 1.3, 5.7) and had made his/her donation intentions known (OR = 4.35, CI = 2.6, 7.3), and when the next-of-kin had more favorable organ donation beliefs (OR = 8.72, CI = 5.2, 14.7), was approached about donation by an OPO coordinator (OR = 3.74, CI = 2.2, 6.4), viewed the requestor as sensitive to their needs (OR = 2.70, CI = 1.6, 4.5) and perceived the timing of the request as optimal (OR = 6.63, CI = 3.6, 12.1) (total regression model, chi square = 133.2, p < 0.001, 92.7% of cases correctly predicted). Findings highlight the need for continued public education efforts to maximize positive beliefs about organ donation, to share and document donation decisions and to improve communication processes among the OPO personnel, hospital staff and prospective donor families. PMID:16433774

  16. Breast milk donation after neonatal death in Australia: a report.

    PubMed

    Carroll, Katherine E; Lenne, Brydan S; McEgan, Kerri; Opie, Gillian; Amir, Lisa H; Bredemeyer, Sandra; Hartmann, Ben; Jones, Rachel; Koorts, Pieter; McConachy, Helen; Mumford, Patricia; Polverino, Jan

    2014-01-01

    Lactation and breast milk can hold great value and meaning for grieving mothers who have experienced a recent death of an infant. Donation to a human milk bank (HMB) as an alternative to discarding breast milk is one means of respecting the value of breast milk. There is little research, national policy discussion, or organizational representation in Australia on the subject of breast milk donation after infant death. On 29 November 2013 the Mercy Hospital for Women in Melbourne, Australia hosted Australia's first National Stakeholder Meeting (NSM) on the topic of milk donation after neonatal death. The NSM drew together representatives from Australian HMBs, neonatal intensive care units (NICUs) currently using donor human milk, and Australia's chief NICU parent support organization. The NSM was video-recorded and transcribed, and analyzed thematically by researchers. This article reports the seven dominant themes discussed by stakeholders during the NSM: the spectrum of women's lactation and donation experiences after infant death; the roles of the HMB and NICU in meeting the needs of the bereaved donor; how bereaved mothers' lactation autonomy may interface with a HMB's donation guidelines; how milk donation may be discussed with bereaved mothers; the variation between four categories of milk donation after neonatal death; the impact of limited resources and few HMBs on providing donation programs for bereaved mothers in Australia. This article provides evidence from researchers and practitioners that can assist HMB staff in refining their bank's policy on milk donation after infant death, and provides national policy makers with key considerations to support lactation, human milk banking, and bereavement services nation-wide. PMID:25530794

  17. Pulmonary toxicity and environmental contamination: radicals, electron transfer, and protection by antioxidants.

    PubMed

    Kovacic, Peter; Somanathan, Ratnasamy

    2009-01-01

    The atmosphere is replete with a mixture of toxic substances, both natural and man-made. Inhalation of toxic substances produces a variety of insults to the pulmonary system. Lung poisons include industrial materials, particulates from mining and combustion, agricultural chemicals, cigarette smoke, ozone, and nitrogen oxides, among a large number of other chemicals and environmental contaminants. Many proposals have been advanced to explain the mode of action of pulmonary toxicants. In this review we focus on mechanisms of pulmonary toxicity that involve ET, ROS, and OS. The vast majority of toxicants or their metabolites possess chemical ET functionalities that can undergo redox cycling. Such recycling may generate ROS that can injure various cellular constituents in the lung and in other tissues. ET agents include quinones, metal complexes, aromatic nitro compounds, and conjugated iminium ions. Often, these agents are formed metabolically from parent toxicants. Such metabolic reactions are often catalytic and require only small amounts of the offending material. Oxidative attack is commonly associated with lipid peroxidation and oxidation of DNA, and it may result in strand cleavage and 8-OH-DG production. Toxicity is often accompanied by depletion of natural AOs, which further exacerbates the toxic effect. It is not surprising that the use of AOs, both natural in fruits and vegetables, as well as synthetic, may provide protection from the adverse effects of toxicant exposure. The mechanistic framework described earlier is also applicable to some of the more prominent pulmonary illnesses, such as asthma, COPD, and cancer. PMID:19484588

  18. A systematic review of sperm donors: demographic characteristics, attitudes, motives and experiences of the process of sperm donation.

    PubMed

    Van den Broeck, U; Vandermeeren, M; Vanderschueren, D; Enzlin, P; Demyttenaere, K; D'Hooghe, T

    2013-01-01

    BACKGROUND This systematic review aimed first to integrate the current body of knowledge on the demographic, institutional and psychosocial information on sperm donors, and second to provide insight into the actual experiences of men who donate and the attitudes towards potential donation. METHODS Electronic databases (PUBMED, CINAHL, PsycINFO, Embase and Web of Science) were searched with no date restriction using a specific search strategy followed by a snowball strategy. English language peer-reviewed abstracts and full texts were screened for eligibility and the risk of bias was assessed with 15 criteria. Eligibility, quality assessments and data extraction were performed by two independent researchers, resolving disagreement by discussion. RESULTS The initial search retrieved 857 studies and after quality assessment, 29 studies were retained for data extraction. Data from nine countries were obtained. The review synthesis revealed differences and similarities between actual and potential sperm donors on demographic characteristics, financial compensation and attitudes towards anonymity, disclosure and providing information to potential offspring. A number of methodological shortcomings have been identified in the studies investigating sperm donors. CONCLUSIONS Institutional factors (such as recruitment procedures, altruism versus compensation of sperm donors, anonymity versus open-identity donation) and the impact of changing legislation have largely dominated the studies on sperm donation. Furthermore, studies from countries with a bias towards white Western ideology and interpretation were over-represented. This has resulted in a profile of potential and actual sperm donors in terms of demographics, recruitment strategies, motivation for donation and attitudes regarding anonymity, disclosure, recipients and offspring. However, the psychosocial needs and experiences of the donor, and their follow-up and counselling are largely neglected. This review has

  19. [Organ donation after euthanasia. Handle with great care].

    PubMed

    Abdo, W F Farid

    2014-01-01

    Recently, organ donation after euthanasia has been a topic of discussion in the Dutch media and scientific literature. Unfortunately, both the articles in question and the media interviews contained several unsubstantiated statements. This article describes the background of organ donation after euthanasia and refutes some of the recent statements. It discusses why it is expected that organ donation after euthanasia will result in a far fewer additional organ donors that originally stated. In conclusion, euthanasia is a topic that should be handled with great care. PMID:25492739

  20. A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway.

    PubMed

    Jiang, Xian; Li, Li; Ying, Zhengxin; Pan, Chenjie; Huang, Shaoqiang; Li, Lin; Dai, Miaomiao; Yan, Bo; Li, Ming; Jiang, Hui; Chen, She; Zhang, Zhiyuan; Wang, Xiaodong

    2016-07-21

    In response to apoptotic stimuli, mitochondria in mammalian cells release cytochrome c and other apoptogenic proteins, leading to the subsequent activation of caspases and apoptotic cell death. This process is promoted by the pro-apoptotic members of the Bcl-2 family of proteins, such as Bim and Bax, which, respectively, initiate and execute cytochrome c release from the mitochondria. Here we report the discovery of a small molecule that efficiently blocks Bim-induced apoptosis after Bax is activated on the mitochondria. The cellular target of this small molecule was identified to be the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer chain (ETC). The molecule protects the integrity of the ETC and allows treated cells to continue to proliferate after apoptosis induction. Moreover, this molecule blocked dopaminergic neuron death and reversed Parkinson-like behavior in a rat model of Parkinson's disease. PMID:27447985

  1. Role of Religion in Organ Donation-Development of the United Kingdom Faith and Organ Donation Action Plan.

    PubMed

    Randhawa, G; Neuberger, J

    2016-04-01

    At a national policy level, the United Kingdom is at the forefront of recognizing the role of faith and its impact on organ donation. This is demonstrated by the recommendations of the Organ Donation Taskforce, National Institute for Clinical Excellence guidelines on organ donation, All-Party Parliamentary Kidney Group, and National Black, Asian and Minority Ethnic Taskforce Alliance. Evidence to date shows that further thought is required to ensure the active engagement of faith communities with organ donation in the UK. The "Taking Organ Transplantation to 2020" strategy was launched in July 2013 by National Health Service Blood and Transplant (NHSBT) in collaboration with the Department of Health and Welsh, Scottish, and Northern Irish governments and seeks to increase the number of people, from all sections of the UK's multiethnic and multifaith population, who consent to and authorize organ donation in their life. NHSBT seeks to work in partnership with faith leaders and this culminated in a Faith and Organ Donation Summit. Faith leaders highlight that there is a need for engagement at both national and local levels concerning organ donation as well as diagnosis and definition of death. PMID:27234715

  2. 41 CFR 102-37.565 - What is the authority for donations to public bodies?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... for donations to public bodies? 102-37.565 Section 102-37.565 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.565 What is the authority for donations to public bodies? Section 527 of title 40,...

  3. 42 CFR 433.67 - Limitations on level of FFP for permissible provider-related donations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... provider-related donations. 433.67 Section 433.67 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... permissible provider-related donations. (a)(1) Limitations on bona fide donations. There are no limitations on the amount of bona fide provider-related donations that a State may receive without a reduction in...

  4. 41 CFR 102-37.40 - What type of surplus property is available for donation?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... property is available for donation? 102-37.40 Section 102-37.40 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.40 What type of surplus property is available for donation? All surplus property (including property held...

  5. 41 CFR 102-37.40 - What type of surplus property is available for donation?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... property is available for donation? 102-37.40 Section 102-37.40 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.40 What type of surplus property is available for donation? All surplus property (including property held...

  6. 42 CFR 433.67 - Limitations on level of FFP for permissible provider-related donations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... provider-related donations. 433.67 Section 433.67 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... permissible provider-related donations. (a)(1) Limitations on bona fide donations. There are no limitations on the amount of bona fide provider-related donations that a State may receive without a reduction in...

  7. 41 CFR 109-44.701 - Findings justifying donation to public bodies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... donation to public bodies. 109-44.701 Section 109-44.701 Public Contracts and Property Management Federal... UTILIZATION AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.701 Findings justifying donation to public bodies. The Director, Office of Administrative Services...

  8. 41 CFR 102-37.565 - What is the authority for donations to public bodies?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... for donations to public bodies? 102-37.565 Section 102-37.565 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.565 What is the authority for donations to public bodies? Section 527 of title 40,...

  9. 45 CFR 2544.150 - How will accepted donations be recorded and used?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false How will accepted donations be recorded and used... FOR NATIONAL AND COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.150 How will accepted donations be recorded and used? (a) All accepted donations of money and other property will...

  10. 41 CFR 102-37.40 - What type of surplus property is available for donation?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... property is available for donation? 102-37.40 Section 102-37.40 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.40 What type of surplus property is available for donation? All surplus property (including property held...

  11. 41 CFR 102-37.580 - Who is responsible for costs associated with the donation?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... costs associated with the donation? 102-37.580 Section 102-37.580 Public Contracts and Property... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.580 Who is responsible for costs associated with the donation? The recipient public...

  12. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  13. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  14. 41 CFR 109-44.701 - Findings justifying donation to public bodies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... donation to public bodies. 109-44.701 Section 109-44.701 Public Contracts and Property Management Federal... UTILIZATION AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.701 Findings justifying donation to public bodies. The Director, Office of Administrative Services...

  15. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  16. 45 CFR 2544.150 - How will accepted donations be recorded and used?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false How will accepted donations be recorded and used... FOR NATIONAL AND COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.150 How will accepted donations be recorded and used? (a) All accepted donations of money and other property will...

  17. 41 CFR 102-37.565 - What is the authority for donations to public bodies?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... for donations to public bodies? 102-37.565 Section 102-37.565 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.565 What is the authority for donations to public bodies? Section 527 of title 40,...

  18. 41 CFR 102-37.580 - Who is responsible for costs associated with the donation?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... costs associated with the donation? 102-37.580 Section 102-37.580 Public Contracts and Property... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.580 Who is responsible for costs associated with the donation? The recipient public...

  19. 45 CFR 2544.150 - How will accepted donations be recorded and used?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false How will accepted donations be recorded and used... FOR NATIONAL AND COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.150 How will accepted donations be recorded and used? (a) All accepted donations of money and other property will...

  20. 41 CFR 102-37.40 - What type of surplus property is available for donation?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... property is available for donation? 102-37.40 Section 102-37.40 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.40 What type of surplus property is available for donation? All surplus property (including property held...

  1. 41 CFR 102-37.580 - Who is responsible for costs associated with the donation?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... costs associated with the donation? 102-37.580 Section 102-37.580 Public Contracts and Property... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.580 Who is responsible for costs associated with the donation? The recipient public...

  2. 45 CFR 2544.150 - How will accepted donations be recorded and used?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false How will accepted donations be recorded and used... FOR NATIONAL AND COMMUNITY SERVICE SOLICITATION AND ACCEPTANCE OF DONATIONS § 2544.150 How will accepted donations be recorded and used? (a) All accepted donations of money and other property will...

  3. 41 CFR 109-44.701 - Findings justifying donation to public bodies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... donation to public bodies. 109-44.701 Section 109-44.701 Public Contracts and Property Management Federal... UTILIZATION AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.701 Findings justifying donation to public bodies. The Director, Office of Administrative Services...

  4. 42 CFR 433.67 - Limitations on level of FFP for permissible provider-related donations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... provider-related donations. 433.67 Section 433.67 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... permissible provider-related donations. (a)(1) Limitations on bona fide donations. There are no limitations on the amount of bona fide provider-related donations that a State may receive without a reduction in...

  5. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  6. 41 CFR 102-37.40 - What type of surplus property is available for donation?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... property is available for donation? 102-37.40 Section 102-37.40 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY General Provisions Donation Overview § 102-37.40 What type of surplus property is available for donation? All surplus property (including property held...

  7. 41 CFR 102-42.125 - How is donation of gifts or decorations accomplished?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false How is donation of gifts... 42-UTILIZATION, DONATION, AND DISPOSAL OF FOREIGN GIFTS AND DECORATIONS Donation of Foreign Gifts and Decorations § 102-42.125 How is donation of gifts or decorations accomplished? The State Agencies for...

  8. 41 CFR 102-37.580 - Who is responsible for costs associated with the donation?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... costs associated with the donation? 102-37.580 Section 102-37.580 Public Contracts and Property... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.580 Who is responsible for costs associated with the donation? The recipient public...

  9. 36 CFR 1256.36 - When can I appeal decisions about access to donated historical materials?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... about access to donated historical materials? 1256.36 Section 1256.36 Parks, Forests, and Public... DONATED HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.36 When can I appeal decisions about access to donated historical materials? (a) If you wish to appeal a denial of access from...

  10. 36 CFR 1256.30 - How do I obtain access to donated historical materials?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... donated historical materials? 1256.30 Section 1256.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE ACCESS TO RECORDS AND DONATED HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.30 How do I obtain access to donated...

  11. 36 CFR 1256.34 - How long may access to some donated historical materials be denied?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... donated historical materials be denied? 1256.34 Section 1256.34 Parks, Forests, and Public Property... HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.34 How long may access to some donated historical materials be denied? Some donated historical materials are closed for long periods, either...

  12. 36 CFR 1256.30 - How do I obtain access to donated historical materials?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... donated historical materials? 1256.30 Section 1256.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE ACCESS TO RECORDS AND DONATED HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.30 How do I obtain access to donated...

  13. 36 CFR 1256.36 - When can I appeal decisions about access to donated historical materials?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... about access to donated historical materials? 1256.36 Section 1256.36 Parks, Forests, and Public... DONATED HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.36 When can I appeal decisions about access to donated historical materials? (a) If you wish to appeal a denial of access from...

  14. 36 CFR 1256.30 - How do I obtain access to donated historical materials?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... donated historical materials? 1256.30 Section 1256.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE ACCESS TO RECORDS AND DONATED HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.30 How do I obtain access to donated...

  15. 36 CFR 1256.34 - How long may access to some donated historical materials be denied?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... donated historical materials be denied? 1256.34 Section 1256.34 Parks, Forests, and Public Property... HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.34 How long may access to some donated historical materials be denied? Some donated historical materials are closed for long periods, either...

  16. 36 CFR 1256.34 - How long may access to some donated historical materials be denied?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... donated historical materials be denied? 1256.34 Section 1256.34 Parks, Forests, and Public Property... HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.34 How long may access to some donated historical materials be denied? Some donated historical materials are closed for long periods, either...

  17. 36 CFR 1256.30 - How do I obtain access to donated historical materials?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... donated historical materials? 1256.30 Section 1256.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE ACCESS TO RECORDS AND DONATED HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.30 How do I obtain access to donated...

  18. 36 CFR 1256.36 - When can I appeal decisions about access to donated historical materials?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... about access to donated historical materials? 1256.36 Section 1256.36 Parks, Forests, and Public... DONATED HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.36 When can I appeal decisions about access to donated historical materials? (a) If you wish to appeal a denial of access from...

  19. 36 CFR 1256.30 - How do I obtain access to donated historical materials?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... donated historical materials? 1256.30 Section 1256.30 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION PUBLIC AVAILABILITY AND USE ACCESS TO RECORDS AND DONATED HISTORICAL MATERIALS Access to Donated Historical Materials § 1256.30 How do I obtain access to donated...

  20. 41 CFR 102-37.565 - What is the authority for donations to public bodies?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... for donations to public bodies? 102-37.565 Section 102-37.565 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.565 What is the authority for donations to public bodies? Section 527 of title 40,...

  1. 41 CFR 109-44.701 - Findings justifying donation to public bodies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... donation to public bodies. 109-44.701 Section 109-44.701 Public Contracts and Property Management Federal... UTILIZATION AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.701 Findings justifying donation to public bodies. The Director, Office of Administrative Services...

  2. 41 CFR 109-44.701 - Findings justifying donation to public bodies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... donation to public bodies. 109-44.701 Section 109-44.701 Public Contracts and Property Management Federal... UTILIZATION AND DISPOSAL 44-DONATION OF PERSONAL PROPERTY 44.7-Donations of Property to Public Bodies § 109-44.701 Findings justifying donation to public bodies. The Director, Office of Administrative Services...

  3. 41 CFR 102-37.565 - What is the authority for donations to public bodies?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... for donations to public bodies? 102-37.565 Section 102-37.565 Public Contracts and Property Management... 37-DONATION OF SURPLUS PERSONAL PROPERTY Donations to Public Bodies in Lieu of Abandonment/Destruction § 102-37.565 What is the authority for donations to public bodies? Section 527 of title 40,...

  4. Protective Role of Ramipril and Candesartan against Myocardial Ischemic Reperfusion Injury: A Biochemical and Transmission Electron Microscopical Study

    PubMed Central

    Reddy, Rajitha Bodd; Punuru, Priyanka; Chakka, Gopinath; Karunakaran, Gauthaman

    2016-01-01

    The present study was designed to investigate the role of combined administration of Ramipril and Candesartan against in vitro myocardial ischemic reperfusion injury in rat. Male Wistar albino rats were divided into five groups (n = 6) and treated with saline (10 mL/kg), Ramipril (2 mg/kg), Candesartan (1 mg/kg), and the combination of both drugs, respectively 24 h before induction of global ischemia (5 min of stabilization, 9 min of global ischemia, and 12 min of reflow). Combination of Ramipril and Candesartan when compared to the monotherapy significantly increased the levels of superoxide dismutase, reduced glutathione, catalase, and nitric oxide and decreased the levels of thiobarbituric acid reactive substances. In addition, the superior protective role of combination of Ramipril and Candesartan on ischemia induced myocardial damage was further confirmed by well preserved myocardial tissue architecture in light microscopy and transmission electron microscopy analysis studies. The combination was proved to be effective in salvaging the myocardial tissue against ischemic reperfusion injury when compared to the monotherapy of individual drugs and further investigations on protective mechanism of drugs by increasing the nitric oxide level at molecular levels are needed. PMID:27042175

  5. A semantic framework to protect the privacy of electronic health records with non-numerical attributes.

    PubMed

    Martínez, Sergio; Sánchez, David; Valls, Aida

    2013-04-01

    Structured patient data like Electronic Health Records (EHRs) are a valuable source for clinical research. However, the sensitive nature of such information requires some anonymisation procedure to be applied before releasing the data to third parties. Several studies have shown that the removal of identifying attributes, like the Social Security Number, is not enough to obtain an anonymous data file, since unique combinations of other attributes as for example, rare diagnoses and personalised treatments, may lead to patient's identity disclosure. To tackle this problem, Statistical Disclosure Control (SDC) methods have been proposed to mask sensitive attributes while preserving, up to a certain degree, the utility of anonymised data. Most of these methods focus on continuous-scale numerical data. Considering that part of the clinical data found in EHRs is expressed with non-numerical attributes as for example, diagnoses, symptoms, procedures, etc., their application to EHRs produces far from optimal results. In this paper, we propose a general framework to enable the accurate application of SDC methods to non-numerical clinical data, with a focus on the preservation of semantics. To do so, we exploit structured medical knowledge bases like SNOMED CT to propose semantically-grounded operators to compare, aggregate and sort non-numerical terms. Our framework has been applied to several well-known SDC methods and evaluated using a real clinical dataset with non-numerical attributes. Results show that the exploitation of medical semantics produces anonymised datasets that better preserve the utility of EHRs. PMID:23228807

  6. Donated materials in assisted reproductive technologies: an ethico-legal analysis of art legislations worldwide

    PubMed Central

    Zawawi, Majdah

    2010-01-01

    This paper provides an appraisal of countries that have legislations pertaining to assisted reproductive technologies (ART). In doing so, the paper highlights the emphasis on the protection of reproductive freedom of the couples seeking ART treatment. This belief is grounded primarily on the basic notion of liberalism that attaches primary importance to respect for individual freedom, which is the foundation of the notion of reproductive rights as understood by western standards today. The main aim of the appraisal is to see how these legislations address the drastic changes in familial relationships when ART involves the use of donated materials. PMID:23908737

  7. Incentive models to increase living kidney donation: encouraging without coercing.

    PubMed

    Israni, Ajay K; Halpern, Scott D; Zink, Sheldon; Sidhwani, Sonal A; Caplan, Arthur

    2005-01-01

    Kidney transplantation is a superior treatment strategy than chronic dialysis for end-stage renal disease patients. However, there is a severe shortage of cadaveric kidneys that are available for transplantation. Therefore many patients are turning to living donors. We describe four models of incentives to improve rates of living kidney donation: the market compensation model, the fixed compensation model, no-compensation model and the expense reimbursement model. We discuss the advantages and disadvantages of each of these models. Any incentive to improve rates of living kidney donation must be accompanied by safeguards. These safeguards will prevent living donors from being viewed primarily as a resource for transplants. These safeguards will also prevent vulnerable individuals from being coerced into donation and will monitor long-term outcomes of donors using a donor registry. We recommend the use of the expense reimbursement model along with these safeguards, in order to increase rates of living kidney donation. PMID:15636607

  8. Intensive care medicine and organ donation: exploring the last frontiers?

    PubMed

    Escudero, D; Otero, J

    2015-01-01

    The main, universal problem for transplantation is organ scarcity. The gap between offer and demand grows wider every year and causes many patients in waiting list to die. In Spain, 90% of transplants are done with organs taken from patients deceased in brain death but this has a limited potential. In order to diminish organ shortage, alternative strategies such as donations from living donors, expanded criteria donors or donation after circulatory death, have been developed. Nevertheless, these types of donors also have their limitations and so are not able to satisfy current organ demand. It is necessary to reduce family denial and to raise donation in brain death thus generalizing, among other strategies, non-therapeutic elective ventilation. As intensive care doctors, cornerstone to the national donation programme, we must consolidate our commitment with society and organ transplantation. We must contribute with the values proper to our specialization and try to reach self-sufficiency by rising organ obtainment. PMID:25841298

  9. [Organ donation from the viewpoint of the medical students].

    PubMed

    Strenge, H

    1998-11-01

    A questionnaire survey was carried out to examine the attitudes of 125 medical students, aged 19-37 years, toward organ donation. 73 of them were in their first semester and 52 senior students in their last year of the study. A return rate of 88% (senior students: 58%) was achieved. Although 59% (71%) expressed willingness to donate their organs, only 30% (50%) had signed an organ donor card. Concerns regarding definition and declaration of death, benefit of organ donation and feelings of the donor's family were identified in 51% (38%) of the students. 71% (79%) had already discussed this issue with their families. In summary, results of the study indicate that more intensified interdisciplinary discussion and information during the study of medicine could bring about an even more positive attitude toward organ donation. PMID:9857723

  10. Racially conditional donation: the example of umbilical cord blood.

    PubMed

    Komesaroff, Paul A; Kerridge, Ian H; Stewart, Cameron; Samuel, Gabrielle; Lipworth, Wendy; Jordens, Christopher F C

    2012-03-01

    While direction of donated tissue to family members has long been accepted, direction to members of specific racial groups has been opposed, on the basis that it is discriminatory and contrary to the ethos the institution of organ donation seeks to promote. It has, however, recently been proposed that racially conditional donation may provide a useful--and ethically acceptable--way to address the social inequalities and injustices experienced by certain cultural groups. This article examines the ethical, legal and cultural arguments for and against racially conditional donation, concluding that the practice is more likely to undermine the values of equity and justice than to promote them and that it may also lead to other unfavourable personal and social outcomes. PMID:22558904

  11. Experiencing organ donation: feelings of relatives after consent1

    PubMed Central

    Fernandes, Marli Elisa Nascimento; Bittencourt, Zélia Zilda Lourenço de Camargo; Boin, Ilka de Fátima Santana Ferreira

    2015-01-01

    Objective: to identify experiences and feelings on the organ donation process, from the perspective of a relative of an organ donor in a transplant unit. Method: this was exploratory research using a qualitative approach, performed with seven family members of different organ donors, selected by a lottery. Sociodemographic data and the experiences regarding the donation process were collected through semi-structured interviews. The language material was transcribed and submitted to content analysis. Results: poor sensitivity of the medical staff communicating the relative's brain death - the potential donor - and the lack of socio-emotional support prior to the situation experienced by the family was highlighted by participants. Conclusions: the study identified the need to provide social-emotional support for families facing the experience of the organ donation process. From these findings, other care and management practices in health must be discussed to impact the strengthening of the family ties, post-donation, as well as the organ procurement indexes. PMID:26487140

  12. Donated Blood Won't Transmit Alzheimer's, Parkinson's Disease

    MedlinePlus

    ... fullstory_159577.html Donated Blood Won't Transmit Alzheimer's, Parkinson's Disease Swedish study of nearly 1.5 ... who have received blood transfusions from patients with Alzheimer's or Parkinson's disease," said Dr. Irving Gomolin, a ...

  13. Eye Donation and Corneal Transplantation: Frequently Asked Questions

    MedlinePlus

    Find an Eye Bank Member Login × Who We Are What We Do Cornea Donation Volunteer Leadership Board of Directors Committees Staff Find an Eye Bank Governing Documents Bylaws Mission/Vision/Values Principles of ...

  14. Blood Transfusion and Donation - Multiple Languages: MedlinePlus

    MedlinePlus

    ... Supplements Videos & Tools You Are Here: Home → Multiple Languages → All Health Topics → Blood Transfusion and Donation URL of this page: https://medlineplus.gov/languages/bloodtransfusionanddonation.html Other topics A-Z A B ...

  15. Non-heart-beating organ donation: process and review.

    PubMed

    Edwards, J M; Hasz, R D; Robertson, V M

    1999-05-01

    To combat the national shortage of donor organs and meet the needs of more than 60,000 patients awaiting transplant, many organ procurement organizations have reevaluated non-heart-beating organ donation (NHBD) as one solution. Non-heart-beating donation is the process by which organs are recovered from patients after the pronouncement of death by cardiopulmonary criteria. Recent media reports have misled health care providers to believe that this is a new donation procedure; however, NHBD provided the foundation for modern clinical transplantation. This article describes non-heart-beating donor evaluation criteria, the donation process, associated ethical considerations and the role of the advance practice nurse in assisting families with this end-of-life decision. A case study will be presented followed by a summary of transplant recipient patient and graft survival outcomes. PMID:10578715

  16. Blood Transfusion and Donation - Multiple Languages: MedlinePlus

    MedlinePlus

    ... Supplements Videos & Tools You Are Here: Home → Multiple Languages → All Health Topics → Blood Transfusion and Donation URL ... this page: https://www.nlm.nih.gov/medlineplus/languages/bloodtransfusionanddonation.html Other topics A-Z A B ...

  17. Attitude and willingness of high school students toward organ donation.

    PubMed

    Afshar, Reza; Sanavi, Suzan; Rajabi, Mohammad-Reza

    2012-09-01

    Public awareness of organ donation fundamentally affects the organ transplantation programs. This study was performed to assess the attitude and willingness of high school adolescents regarding organ donation. The study population consisted of 416 high school girls who were studying in four grades of three educational courses. Data were collected by a questionnaire and included demographic variables and attitude and willingness, which were assessed based on the Likert scale. The SPSS v.16 was used for data analysis. The mean age of the study subjects was 16.26 ± 1.06 years, 31% studied in grade-1, 27% in grade-2 (25% natural sciences, 27% mathematics and 48% humanities), 26% in grade-3 (30% natural sciences, 34% mathematics and 36% humanities) and 16% in pre-university stage (32% natural sciences, 42% mathematics and 26% humanities). The students had a highly positive attitude toward organ donation (mean score 4.2 ± 0.54). The greatest willingness for organ donation was concerning the kidney (88%) and heart (84%), followed by the liver (83.4%), pancreas (79.6%), cornea (67.8%) and skin (51%). Willingness for deceased as well as living organ donation was indicated by 92% and 47%, respectively, of the participants. Organ donation was considered acceptable only to relatives by 5% of the participants when the donors were deceased donors and by 16% of the participants when the donors were living donors; donation to all needy persons from deceased donors was accepted by 87% of the participants and from living donors by 31%. The purpose of donation was stated as lending help to others by 89% and progression of science by 40.2% of the participants. Willingness for organ donation from a deceased relative was declared by 63% of the students. There was significant positive correlation between willingness for organ donation and attitude (P <0.001). In addition, attitude and willingness had positive correlation with educational levels, age and educational courses. Our study

  18. Donation after cardiac death and the emergency department: ethical issues.

    PubMed

    Simon, Jeremy R; Schears, Raquel M; Padela, Aasim I

    2014-01-01

    Organ donation after cardiac death (DCD) is increasingly considered as an option to address the shortage of organs available for transplantation, both in the United States and worldwide. The procedures for DCD differ from procedures for donation after brain death and are likely less familiar to emergency physicians (EPs), even as this process is increasingly involving emergency departments (EDs). This article explores the ED operational and ethical issues surrounding this procedure. PMID:24552527

  19. [The costs of altruism in organ donation case analysis].

    PubMed

    Netza Cardoso, Cruz; Casas Martínez, María Luz Lina; Ramírez García, Hugo

    2010-01-01

    Three main assumptions were considered for the structure of donation programs during the decade of the sixties: the first states that people, through altruism, would feel committed with the affected and therefore incentivized to donate. The second one states that the human body can not be valued in mercantile terms; therefore organ donation should not be done free of any charges. The last one states donation does not represent any type of harm or damage for the donor. Today, more tan four decades away from their instauration, these three assumptions have been violated and modified due to the way in which they were socialized through the donation protocols. Altruism did not seem to be as generalized as expected, and organ commerce has already gone beyond the legislative frameworks that intended to prevent it; one example is the case of India. In this paper we analyze--through two objectives--the repercussions and impact that took effect in four cases registered in the National Institute of Cardiology (Instituto Nacional de Cardiología) "Ignacio Chávez" in Mexico City. First objective: to describe the economical costs that the altruism-based donation protocol caused on the participant families. Second objective: to reflect on other costs that affected donators due to organ donation. It was found on the reviewed cases that repercussions can go beyond the economical issues; labor related, emotional and ethical repercussions were found too due to a undeniable sensation of reification that donors experience in view of the mechanization of the study protocol they undergo, specially when results are not the optimum. We circumscribe this paper’s analysis to living donors. PMID:20886909

  20. [The personalised donation of fresh breastmilk in neonatology].

    PubMed

    Humbert, Gwénaëlle

    2016-01-01

    Donation of fresh breastmilk in neonatology is subject to guidelines set out in a 1997 memorandum and recommendations issued in 2005. The results of a survey carried out in 2013 show that practices in this area vary greatly from one neonatology unit to another. There is a clear need to adopt a national consensus regarding the conditions of this donation in neonatology, in order to adapt and standardise practices. PMID:27177487

  1. Organ transplantation and tissue donation: a theological look.

    PubMed

    Fitzgerald, O R

    1993-01-01

    The author's position is that the work of organ donation and transplantation and tissue donation over the past forty-five years is in need of theological reflection. Some profound events and processes are involved in transplantation as the human family engages in a quest for wholeness. Different religious traditions-Jewish, Catholic, Eastern Orthodox, and Protestant-view the use of organs for transplantation differently. General attribution theory is adapted as a perspective on organ transplantation. PMID:10129259

  2. The perioperative nurse and the organ donation experience.

    PubMed

    Lilly, K T; Langley, V L

    1999-04-01

    Most OR nurses whether veteran or novice have had some exposure to organ donation; however, few are aware of what occurs outside of the surgical setting. This article provides an overview of the entire donation process, from the hours before the procedure to the steps needed for successful recovery. Particular attention is given to the care of the donor family members, both preoperatively and postrecovery. PMID:11838090

  3. Role of urgent care staff in organ donation.

    PubMed

    Garside, Marie; Garside, Jules

    2010-10-01

    A detailed review of donation activity since the introduction of an embedded specialist nurse in organ donation (SNOD) in Norfolk and Norwich University Hospitals NHS Foundation Trust has confirmed the benefits of this role for the identification and referral of potential donors by emergency department (ED) staff. This article argues that, as EDs across the U.K. introduce SNODs, more organs will become available for transplant. PMID:21066923

  4. Does living donation have advantages over deceased donation in liver transplantation?

    PubMed

    Kaido, Toshimi; Uemoto, Shinji

    2010-10-01

    Liver transplantation (LT) is the best treatment option for patients with end-stage liver disease. Living donor LT (LDLT) has developed as an alternative to deceased donor LT (DDLT) in order to overcome the critical shortage of deceased organ donations, particularly in Asia. LDLT offers several advantages over DDLT. The major advantage of LDLT is the reduction in waiting time mortality. Especially among patients with hepatocellular carcinoma (HCC), LDLT can shorten the waiting time and lower the dropout rate. The Hong Kong group reported that median waiting time was significantly shorter for LDLT than for DDLT. Intention-to-treat survival rates of HCC patients with voluntary live donors were significantly higher than those of patients without voluntary live donors. In contrast, a multicenter adult-to-adult LDLT retrospective cohort study reported that LDLT recipients displayed a significantly higher rate of HCC recurrence than DDLT recipients, although LDLT recipients had shorter waiting times than DDLT recipients. The advantage of LDLT involves the more liberal criteria for HCC compared with those for DDLT. Various preoperative interventions including nutritional treatment can also be planned for both the donor and recipient in LDLT. Conversely, LDLT has marked unfavorable characteristics in terms of donor risks. Donor morbidity is not infrequent and the donor mortality rate is estimated at around 0.1-0.3%. In conclusion, living donation is not necessarily advantageous over deceased donation in LT. Taking the advantages and disadvantages of each option into consideration, LDLT and DDLT should both be used to facilitate effective LT for patients requiring transplant. PMID:20880167

  5. Directed altruistic living organ donation: partial but not unfair.

    PubMed

    Hilhorst, Medard T

    2005-04-01

    Arguments against directed altruistic living organ donations are too weak to justify a ban. Potential donors who want to specify the non-related person or group of persons to receive their donated kidney should be accepted. The arguments against, based on considerations of motivation, fairness and (non-)anonymity (e.g. those recently cited by an advisory report of the Dutch Health Council), are presented and discussed, as well as the Dutch Government's response. Whereas the Government argues that individuals have authority with regard to the allocation of their organs, partial considerations have not been sufficiently explored. In addition, it is argued that partial relationships govern human life, are significant and should be valued highly. These relationships are at the core of accepted living kidney donation between relatives (family members, partners, friends). Respecting the particular act of living donation goes beyond respect for autonomy; it touches upon our personal and social identity. Donation, e.g. of a kidney, is not undertaken strictly for the benefit of the recipient, but also to meet the moral standards we wish to set for ourselves. This consideration, rooted in a view of moral identity, provides the basis for many forms of directed donation that are both partial and justified. If the importance of this is not recognized, social policies can be neither adequate nor effective. PMID:16459404

  6. Human body donation programs in Sri Lanka: Buddhist perspectives.

    PubMed

    Subasinghe, Sandeepani Kanchana; Jones, D Gareth

    2015-01-01

    Considerable attention is being given to the availability of bodies for anatomical education. This raises the question of the manner in which they are obtained, that is, whether they are unclaimed or donated. With increasing emphasis upon the ethical desirability of using body bequests, the spotlight tends to be focused on those countries with factors that militate against donations. However, little attention has been paid to cultures where donations are readily available. One such country is Sri Lanka where the majority of the Buddhist population follows Theravada Buddhism. Within this context, the expectation is that donations will be given selflessly without expecting anything in return. This is because donation of one's body has blessings for a better outcome now and in the afterlife. The ceremonies to honor donors are outlined, including details of the "Pirith Ceremony." The relevance for other cultures of these features of body donation is discussed paying especial attention to the meaning of altruism and consent, and justification for the anonymization of cadavers. The degree to which anatomy is integrated into the surrounding culture also emerges as significant. PMID:25689145

  7. Safety of Living Donation of Hematopoietic Stem Cells.

    PubMed

    Szer, Jeff; Elmoazzen, Heidi; Fechter, Mirjam; Hwang, William; Korhonen, Matti; Miller, John; Mengling, Thilo; Shaw, Bronwen; Stein, Jerry

    2016-06-01

    More than 12 000 volunteer unrelated hematopoietic stem cell donations are undertaken annually, and the World Marrow Donor Association established an expert committee to examine all reports of adverse events affecting donors globally, eventually making such reporting a necessary part of World Marrow Donor Association accreditation. The committee evaluates and responds to reported events in a nonpunitive confidential process designed to alert the community of rare events which might be missed by local follow-up. Each report is evaluated by the committee for imputability (causal link between the donation and the adverse event) and compared with that submitted by the reporting registry. In 2014, there were 50 reports received from 16 different registries in 15 countries. There were 16 reports of malignancies arising in donors including 3 hematologic malignancies. All but 2 of the 16 occurred more than a year after donation. There were 4 reports of autoimmune phenomena in donors all occurring more than a year postdonation. Of the 30 remaining events, 6 were allergic, 4 cardiac, 3 gastrointestinal, 2 infections, 2 pulmonary, and 13 miscellaneous. Causation was assessed differently to the reporting registry in 17 events with 6 thought to be less likely causally linked to the donation and 10 more likely with 1 requiring more information. Volunteer unrelated hematopoietic stem cell donation is a safe and effective altruistic contribution to the treatment of patients with life-threatening hematologic disorders. A decade of detailed examination of adverse donor events has contributed to the safety of these donations. PMID:27136264

  8. EFFECTS OF MESSAGE FRAMING AND EXEMPLARS ON PROMOTING ORGAN DONATION.

    PubMed

    Chien, Yu-Hung; Chang, Wen-Te

    2015-12-01

    People in many countries are unwilling to donate organs. Drawing on previous research regarding the use of message framing and the theory of exemplification promoting intentions to donate organs, this study examined messaging strategies. This study used a 2 × 2 between-subjects factorial design to examine the joint effects of gain/loss frames and statistical/exemplar appeals on the intentions of 189 Taiwanese college students (108 women, 81 men; age range = 19-24 yr., M = 21.6, SD = 2.9) regarding organ donation. Each participant was randomly assigned to read one of four versions of an organ donation promotional message and then to complete a questionnaire. The analysis of variance showed a significant interaction between the two factors. Loss-exemplar messages elicited significantly more positive intentions toward donation than did loss-statistical messages. There was no significant difference between the statistical and exemplar appeals observed under the gain-framed condition. The practical implications of developing effective organ donation promotional materials and the limitations of this study are discussed. PMID:26595292

  9. The physician's role in discussing organ donation with families.

    PubMed

    Williams, Michael A; Lipsett, Pamela A; Rushton, Cynda H; Grochowski, Eugene C; Berkowitz, Ivor D; Mann, Stephen L; Shatzer, John H; Short, M Priscilla; Genel, Myron

    2003-05-01

    Federal Conditions of Participation from the Health Care Financing Administration (now the Centers for Medicare and Medicaid Services) introduced in 1998 require that all families be presented the option of organ and tissue donation when death is imminent. The perception that physicians were being excluded from participating in this process led to a resolution at the American Medical Association House of Delegates meeting in December 1999, calling on the American Medical Association Council on Scientific Affairs to review the Conditions of Participation "to ensure that there is no prohibition of physician involvement in the organ donation process..." The number of organs procured for transplantation in the United States is insufficient to meet needs. Families' hospital experiences significantly affect their decisions to donate organs. Discussing severe brain injury, brain death, and organ donation after brain death with families is a specialized form of end-of-life decision-making and care in the intensive care unit; however, the knowledge, skills, and attitudes necessary for physicians and nurses to promote good end-of-life decision-making are widely variable. The federal Conditions of Participation require that those making requests of families for organ donation receive specific training. They do not prohibit physician involvement in initiating organ donation requests, provided these individuals are properly trained. Physicians have an important role in caring for patients and families in these circumstances, and the care they provide is enhanced through training, attention to the special issues involved, and collaboration with organ procurement organization personnel. PMID:12771634

  10. [Blood donation: Representations and issues associated with blood product collection].

    PubMed

    Loquier, B; Zegierman, A; Pelletier, B

    2015-08-01

    In order to answer to its aim of standardised self-sufficiency, the Établissement français du sang (main French national platform for blood donation) needs to know well the donors, what moves them, what motivates them, and the meaning that they give to their action. This knowledge allows the EFS to better understand the different sensitivities among donors, and therefore to improve the strategy regarding loyalty or/and newcomers. In this paper we follow, without attempting to be fully exhaustive, the evolution of the research regarding blood donation. The aim is to highlight the role played by social and historical representations regarding donation in general. In a given community, its norms, and its values influence both the image of donors as well as the meaning attached to the act itself of donation. Moreover, these norms have also influenced the way that research has tried to analyse this topic. The initial studies conducted in this field tried generally to understand the meaning and the symbolism attached to the act of blood donation. Later on, researchers started to focus on the assessment of notions such as generosity, and then solidarity. Nowadays, research is more focused on describing the population that gives blood. They are more scrutinised through their socio-demographic traits (who they are) than through the specific study of how they donate, the reasons behind the decision to act and the notion of satisfaction. PMID:26112917

  11. Gender issues in solid organ donation and transplantation.

    PubMed

    Ge, Fangmin; Huang, Tao; Yuan, Shunzong; Zhou, Yeqing; Gong, Weihua

    2013-01-01

    Gender as a critical, intrinsic, non-immunologic factor plays a pivotal role in the field of transplantation. The gender of donors and recipients is involved in the entire process, including organ donation and transplant surgery. This review article aims to summarize the literature related to the role of gender in solid organ donation and transplantation and to unveil the underlying mechanism by which gender mismatch between donor and recipient impacts transplant rejection. A systematic search was conducted through PubMed by using the following key words: "gender", or "sex", and "transplant", "organ donation" for published articles. The prima facie evidence demonstrated that females are more likely to donate their organs and are less willing than males to accept transplant surgery; however, their donated liver organs will have a higher risk of graft failure compared with males. With respect to kidney, heart, and lung transplantations, the role of gender remains controversial. Results of animal studies support the negative impact of gender mismatch on allograft function. In conclusion, our present study advances the knowledge of gender issues in the field of solid organ donation and transplantation. In general, gender mismatch is not advantageous to transplant outcome, as evidenced by many aspects of biological investigations on immunogenicity of H-Y antigen to females. Therefore, gender issues should be highlighted and an a priori intervention is needed to improve graft survival in clinical practice. PMID:24064859

  12. Donor identification 'kills gamete donation'? A response.

    PubMed

    Allan, Sonia

    2012-12-01

    Two Australian government inquiries have recently called for the release of information to donor-conceived people about their gamete donors. A national inquiry, recommended 'as a matter of priority' that uniform legislation to be passed nationwide. A state-based inquiry argued that all donor-conceived people should have access to information and called for the enactment of retrospective legislation that would override donor anonymity. This paper responds to an opinion piece published in Human Reproduction in October 2012 by Professor Pennings in which he criticized such recommendations and questioned the motives of people that advocate for information release. I answer the arguments of Pennings, and argue that all parties affected by donor conception should be considered, and a compromise reached. The contact veto system is one such compromise. I discuss the education and support services recommended by the Victorian government and question Pennings' assertions that legislation enabling information release will lead to a decrease in gamete donation. Finally, I rebut Pennings' assertion that there is a 'hidden agenda' behind the call for information release. There is no such agenda in my work. If there is from others, then it is their discriminatory views that need to be addressed, not the move toward openness and honesty or the call for information by donor-conceived people. PMID:23034154

  13. Cardiac failure, transplantation and donation: current perspectives.

    PubMed

    Ashraf, O; Sharif, H

    2015-08-01

    Cardiac failure remains a significant source of morbidity and mortality worldwide. Multiple treatment options exist and have variable safety and reliability. Stem cell grafting and left ventricular assist device implantation are two of the promising recent techniques that have a bright future as transient and permanent therapies for end-stage heart failure. For the moment though they serve largely as bridges to cardiac transplantation, the definitive management of the failing heart. Cardiac transplantation itself is facing a number of challenges that limit its widespread usage globally. This review aims to obtain current perspectives on heart failure treatment, particularly among the three abovementioned modalities, whilst highlighting briefly some of the other novel treatment alternatives emerging globally. A comprehensive review of literature is undertaken from the past few years to understand the recent advancements, knowledge and research trends in this arena. An attempt is also made to understand the factors limiting the employment of modern management principles in the treatment of heart failure in the developing world, with particular emphasis on cardiac donation and transplantation; and the steps that could be taken to improve the desperately low recipient to donor ratio across the globe. PMID:23719618

  14. No-carrier-added (NCA) aryl ([sup 18]F) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

    DOEpatents

    Yushin Ding; Fowler, J.S.; Wolf, A.P.

    1993-10-19

    A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.

  15. No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

    DOEpatents

    Ding, Yu-Shin; Fowler, Joanna S.; Wolf, Alfred P.

    1993-01-01

    A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.

  16. [Gamete donation in an in vitro fertilization program].

    PubMed

    Zhang, L Z

    1993-12-01

    Two cases of gamete donation in an IVF program were reported in this paper. In the first case the wife with recurrent abortions was found to have chromosomal abnormality, her karyotype was 45,XX,-14,-14 + rob (14 Q 14 Q). She became pregnant after IVF-ET with donated ova, and was delivered of a normal male baby on June 12, 1992. The baby's karyotype was normal. The blood group of both the husband and wife was O, while that of the baby was B. The baby suffered from icterus neonatorum as a result of ABO incompatibility but recovered quickly after treatment. Further DNA finger print analysis of the husband, wife and baby, combined with the history of egg donation IVF, proved the relationship of the parents with the baby. In the second case the husband's karyotype was 46,XY, t(4; 9) (4Q+; 9Q-). The wife had also history of recurrent abortions. Since 1989, the wife received sperm donation IUI 5 times in another hospital without success. IVF-ET with donated sperms was performed in November 1991 resulting in clinical pregnancy. She was delivered of a pair of twins, one male and one female on July 20, 1992. The possibilities of different types of gamete formation during meiosis in carriers of chromosomal balanced translocation were briefly discussed. Donation of oocytes could be realized only in an IVF program, which is also the only way to propagate for the family. However, IVF with donated sperms is indicated in women with blocked tubes besides the male factor or after repeated failures of other assisted reproductive technologies. PMID:8137642

  17. Factors Associated with Repeat Blood Donation at the Northern Zone Blood Transfusion Centre in Tanzania

    PubMed Central

    Mauka, Wilhellmuss I.; Mahande, Michael J.; Msuya, Sia E.; Philemon, Rune N.

    2015-01-01

    Background and Objective. The aim of this study was to determine factors associated with repeat blood donation. Methods. This was a cross-sectional study carried out among blood donors aged 18–65 years in northern Tanzania. The questionnaire was administered among 454 participants through the phone. Results. Of the 454 participants, the proportion of repeat donation was 63.9%. In the backward logistic regression analysis, the significant predictors were living in Arusha which had lower odds of repeat donation compared to those living in Kilimanjaro. Knowledge of time interval between donations increased odds of repeating donations. High intention increased odds of repeat donation compared to low intention. Altruistic score had minor effect on increasing odds of repeating donation. Conclusion. Repeat blood donation is affected by proximity of donating site, awareness of the blood donation interval, intention to donate, and experience on previous donation. We recommend continuous education concerning blood donors and donation among health workers and society as a whole; this will create awareness on motivational factors for repeat donations. PMID:26783496

  18. Human autonomic responses to blood donation.

    PubMed

    Zöllei, Eva; Paprika, Dóra; Makra, Péter; Gingl, Zoltán; Vezendi, Klára; Rudas, László

    2004-02-27

    In order to characterize autonomic responses to acute volume loss, supine ECG, blood pressure (BP) and uncalibrated breathing signal (UBS) recordings were taken before and after blood donation in 48 healthy volunteers. Time and frequency domain parameters of RR interval (RRI), BP and UBS variability were determined. Baroreflex gain was calculated by the technique of the spontaneous sequences and cross-spectral analysis. The systolic (SAP), diastolic (DAP) and mean BP (MAP) increased after the blood withdrawal. The central frequency of breathing and mean heart rate did not change. RRI variability increased in low frequency band (LF), tended to decrease in high frequency band (HF). Systolic BP variability increased in both frequency bands, but was statistically significant only in the high frequency band. Diastolic BP power increased in both frequencies. From the different baroreflex gain estimates, up sequence BRS and HF alpha index decreased significantly. The phase angle between RRI and systolic blood pressure powers in LF band did not change (-58 +/- 24 degrees and -54 +/- 26 degrees ). In the high frequency range, the phase became more negative (-1 +/- 29 degrees and -17 +/- 32 degrees, p = 0.001). The withdrawal of 350-400 ml blood in 5 min resulted in sympathetic activation, which was reflected in increased systolic, diastolic and mean BP. The increased BP oscillation was a sensitive marker of the minor volume depletion. This was coupled by increased RRI oscillation via baroreflex mechanisms in the LF band. Changes in the RRI and BP oscillations in the HF band showed no similar coupling. That points to the fact that RRI oscillations in this band should not be explained entirely by baroreflex mechanisms. Vagal withdrawal was reflected in decreased root mean square of successive differences (RMSSD), decreased HF RRI power and decreased up sequence BRS. PMID:15046735

  19. Ultrastructural investigations on protective effects of NCX 4016 (nitroaspirin) on macrovascular endothelium in diabetic Wistar rats.

    PubMed

    Ambrosini, M V; Mariucci, G; Rambotti, M G; Tantucci, M; Covarelli, C; De Angelis, L; Del Soldato, P

    2005-08-01

    The effect of a nitric oxide-donating aspirin derivative, 2-acetoxy-benzoate 3-(nitroxy-methyl)phenyl ester (NCX 4016), and aspirin on the aortic endothelium of diabetic rats was investigated by using scanning and transmission electron microscopy. Control and streptozotocin-treated rats were used. Metabolic control was assessed by measuring blood and urine metabolites, and 24-h urine volume. The ultrastructural study was performed after 7 weeks of diabetes and 6 weeks of therapy. Streptozotocin treatment induced a persistent hyperglycemia which was not influenced by the pharmacological treatments. Values of blood metabolites were in line with the diabetic status. Both scanning and transmission electron microscopy revealed that aortic endothelium was severely damaged in all diabetic rats except for the NCX 4016 treated ones. Our data document the protective effects of NCX 4016 on the vascular endothelium of diabetic rats. Since aspirin had no protective action, NCX 4016 may have exerted its beneficial action by releasing nitric oxide. PMID:16335593

  20. The electronic solid-state switch /ELS3/ - An automatic protection for spacecraft high-power lines

    NASA Astrophysics Data System (ADS)

    Capel, A.; Osullivan, D.; Levins, D.; Rossel, P.; Ferrante, J. G.

    The basic principles and performance characteristics of the electronic solid-state switch (ELS3), designed as a high-reliability alternative to electromechanical relays and fuses for satellite power-conditioning systems, are discussed. The ELS3 functions by limiting the current flowing through it to a value causing no damage to the networks at either end, while itself having two different types of autoprotection: a fold-back characteristic which reduces the maximum current limit, and active control of chip crystal temperatures. The switch is based on MOSFET and high-power thick film technology for the power stage, allowing the reliable paralleling of components for high currents, and an active thermal control to supplement the self-protection capability in the event of an overstress. An overall thermal analysis performed using the ESACAP simulation program has shown the circuit to react as a micro-temperature controller, preventing the destructive thermal dissipation of the power silicon chips. Experimental breadboard measurements have confirmed the thermal analysis.

  1. Communicating Effectively About Organ Donation: A Randomized Trial of a Behavioral Communication Intervention to Improve Discussions About Donation

    PubMed Central

    Siminoff, Laura A.; Traino, Heather M.; Genderson, Maureen Wilson

    2015-01-01

    Background Families’ refusal to authorize solid organ donation contributes to the organ deficit in the United States. The importance of communication to reducing refusal to requests for solid organ donation at the bedside and thus increasing the supply of transplantable organs cannot be overstated. This research compares 2 versions of an innovative communication skills training program for organ procurement organization request staff, Communicating Effectively About Donation (CEaD), designed to improve the quantity and quality of organ donation discussions with family decision makers of deceased patients. Methods We conducted a parallel group randomized controlled trial of the CEaD intervention, comparing an online only version of the training (CEaD1) with the online version bolstered with in-person practice and feedback (CEaD2). Survey and interview data were collected from 1603 family decision makers and 273 requesters to assess the impact of both versions of the CEaD on requesters’ communication skills and behaviors; the rate of family authorization to solid organ donation was obtained from administrative data provided by 9 organ procurement organizations. Results Results revealed higher rates of authorization for requesters with less tenure (78% to 89%, P < 0.03) for both versions; however, CEaD1 also increased authorization rates for requesters with 3 or more years of experience (89% to 92%, P < 0.03). Both conditions resulted in an improvement in overall communication quality. Conclusions We conclude that the CEaD was effective in improving requesters’ communication skills, rates of family authorization to organ donation, and the overall quality of the donation experience. PMID:26146659

  2. Philosophy of organ donation: Review of ethical facets

    PubMed Central

    Dalal, Aparna R

    2015-01-01

    Transplantation ethics is a philosophy that incorporates systematizing, defending and advocating concepts of right and wrong conduct related to organ donation. As the demand for organs increases, it is essential to ensure that new and innovative laws, policies and strategies of increasing organ supply are bioethical and are founded on the principles of altruism and utilitarianism. In the field of organ transplantation, role of altruism and medical ethics values are significant to the welfare of the society. This article reviews several fundamental ethical principles, prevailing organ donation consent laws, incentives and policies related to the field of transplantation. The Ethical and Policy Considerations in Organ Donation after Circulatory Determination of Death outline criteria for death and organ retrieval. Presumed consent laws prevalent mostly in European countries maintain that the default choice of an individual would be to donate organs unless opted otherwise. Explicit consent laws require organ donation to be proactively affirmed with state registries. The Declaration of Istanbul outlines principles against organ trafficking and transplant tourism. World Health Organization’s Guiding Principles on Human Cell, Tissue and Organ Transplantation aim at ensuring transparency in organ procurement and allocation. The ethics of financial incentives and non-financial incentives such as incorporation of non-medical criteria in organ priority allocation have also been reviewed in detail. PMID:26131406

  3. Blood donation by the elderly. Clinical and policy considerations.

    PubMed

    Pindyck, J; Avorn, J; Kuriyan, M; Reed, M; Iqbal, M J; Levine, S J

    1987-03-01

    At present, healthy potential blood donors older than the age of 66 years often leave the donor pool for reasons of age alone, despite the fact that this demographic group is growing, is a potentially willing source of blood products, and constitutes the cohort with highest per capita use of blood and its derivatives. There is no clinical or physiological rationale for this. We performed a controlled study to measure the feasibility and safety of blood donation by healthy elderly donors aged 66 years and older, compared with a younger cohort aged 55 to 65 years of age. A study group of prior donors aged 66 years and older and a control group of prior donors between the ages of 50 and 65 were sent letters inviting them to donate blood. The volume donated did not differ between the two groups. In the older group, there were eight immediate reactions, seven mild and one moderate. The control population experienced seven immediate reactions, six mild and one severe. We conclude that it is both clinically feasible and efficient to recruit healthy prior donors older than the age of 66 years for blood donation. As a group, this population is potentially able to donate large volumes of blood and do so without any difference in immediate or short-term reactions. Further study of hemodynamic variables as more objective markers of safety is needed. PMID:3806916

  4. Psychiatric disorders: are they an absolute contraindication to living donation?

    PubMed

    Rowley, Anthony A; Hong, Barry A; Martin, Susan; Jones, Linda; Vijayan, Anitha; Shenoy, Surendra; Jendrisak, Martin

    2009-06-01

    Little information has been published about the suitability of candidates for living organ donation who have a past or current psychiatric diagnosis. A retrospective review of 445 living donor kidney transplants performed at Barnes-Jewish Hospital's transplant center from 1995 to 2005 disclosed 42 donor candidates with such a history, prompting detailed psychological evaluation. Although 41 candidates (10% of the donor pool) met criteria for 1 or more psychiatric diagnoses, none were considered psychologically unfit for donation. Of these, 22 candidates underwent kidney donation without medical or surgical complications and without development of subsequent active psychological problems. Several donors maintained long-term contact up to 12 years to report good health and a high degree of satisfaction with the decision to donate. This experience suggests that for donor candidates with a psychiatric diagnosis, formal psychiatric evaluation to evaluate current mental health stability is warranted. Stable individuals, on or off therapy, can be considered fit to donate with expected short- and long-term outcome prognoses similar to those for the general population. PMID:19588662

  5. An analysis of a preoperative pediatric autologous blood donation program

    PubMed Central

    Letts, Merv; Perng, Richard; Luke, Brian; Jarvis, James; Lawton, Louis; Hoey, Steve

    2000-01-01

    Objective To determine the efficacy of a pediatric autologous blood donation program. Design A retrospective study of patient charts and blood-bank records. Setting The Children’s Hospital of Eastern Ontario, Ottawa, a tertiary care, pediatric centre. Patients One hundred and seventy-three children who received blood transfusions for a total of 182 procedures between June 1987 and June 1997. Interventions Autologous and homologous blood transfusion required for major surgical intervention, primarily spinal fusion. Main outcome measures Surgeons’ accuracy in predicting the number of autologous blood units required for a given procedure, compliance rate (children’s ability to donate the requested volume of blood), utilization rate of autologous units and rate of allogeneic transfusion. Results The surgeons’ accuracy in predicting the number of autologous units required for a given procedure was 53.8%. The compliance rate of children to donate the requested amount of blood was 80.3%. In children below the standard age and weight criteria for blood donation the compliance rate was 75.5%. The utilization rate of autologous units obtained was 84.4% and the incidence of allogeneic transfusion was 26.6%. Conclusions There was a high rate of compliance and utilization of predonated autologous blood in the children in the study. Preoperative blood donation programs are safe and effective in children, even in those below the standard age and weight criteria of 10 years and 40 kg. PMID:10812347

  6. 'Living choice': the commitment to tissue donation in palliative care.

    PubMed

    Wells, Joanne; Sque, Magi

    2002-01-01

    Professionals working in palliative care pride themselves on respecting patients' views and wishes. Palliative care patients are often aware that they are going to die and so the issue of what is going to happen to them after death becomes more relevant. That they should be involved in decisions about tissue donation seems obvious, yet many palliative care units do not routinely discuss donation with patients and their families. A grounded theory approach was used to develop an explanation of the low commitment to tissue donation by palliative care units. Six registered nurses and two doctors from each of two separate palliative care units participated in semi-structured, audiotaped interviews. Several themes emerged from the interviews to form a theory of why there is a low commitment to tissue donation in palliative care units. We have called the theory 'living choice'. The dominant theme of category was 'patient choice' and this pervaded and influenced 'professional role', 'donation process', 'concerns' and 'knowledge'. All these categories were contained and continuously interacted in the palliative care environment. PMID:11823746

  7. Philosophy of organ donation: Review of ethical facets.

    PubMed

    Dalal, Aparna R

    2015-06-24

    Transplantation ethics is a philosophy that incorporates systematizing, defending and advocating concepts of right and wrong conduct related to organ donation. As the demand for organs increases, it is essential to ensure that new and innovative laws, policies and strategies of increasing organ supply are bioethical and are founded on the principles of altruism and utilitarianism. In the field of organ transplantation, role of altruism and medical ethics values are significant to the welfare of the society. This article reviews several fundamental ethical principles, prevailing organ donation consent laws, incentives and policies related to the field of transplantation. The Ethical and Policy Considerations in Organ Donation after Circulatory Determination of Death outline criteria for death and organ retrieval. Presumed consent laws prevalent mostly in European countries maintain that the default choice of an individual would be to donate organs unless opted otherwise. Explicit consent laws require organ donation to be proactively affirmed with state registries. The Declaration of Istanbul outlines principles against organ trafficking and transplant tourism. World Health Organization's Guiding Principles on Human Cell, Tissue and Organ Transplantation aim at ensuring transparency in organ procurement and allocation. The ethics of financial incentives and non-financial incentives such as incorporation of non-medical criteria in organ priority allocation have also been reviewed in detail. PMID:26131406

  8. Minority Donation in the United States: Challenges and Needs

    PubMed Central

    Shaz, Beth H.; Hillyer, Christopher D.

    2011-01-01

    Purpose of review In the United States, blood donation rates of African American are 25-50% of that of white individuals. As African Americans make up an ever increasing and now substantial minority, and African American recipients of blood transfusion, both specialized, such as sickle cell disease patients, and general hospitalized patients, have a better chance of receiving phenotype-matched or appropriate red blood cell units when there is a significant percent of products in inventory from African American donors, it is important to understand the reason for the observed difference. Recent findings Possible reasons for this discrepancy in donation rates include: 1) increased rates of donor deferral and ineligibility; 2) increased barriers to donation, such as fear and distrust; and 3) different marketing and education strategies. Thus, to increase the blood availability to African American recipients, the reasons for these donation rate differences must be better understood and subsequently addressed through improved blood donor recruitment programs. The majority of African American donor recruitment programs have focused on donating for sickle cell disease patients, particularly children, which have been of limited success. Summary Significant improvements in African American donor recruitment are needed to adequately meet the demand of African American patients as well as the entire population. PMID:20717026

  9. Oocyte donation for reproduction and research cloning--the perils of commodification and the need for European and international regulation.

    PubMed

    Schneider, Ingrid

    2006-01-01

    The demand for women's egg cells is increasing and is leading to reproductive tourism and transnational oocyte trafficking. The article considers the regulatory landscape of oocyte donation in Europe and analyses different types, particularly whether oocytes are provided within or outside of the IVF context, and whether anonymity of the donor is legally possible or not. The bifurcation between different purposes of egg extraction, particularly the challenges raised by ova demands for cloning research (SCNT) are highlighted. In emphasizing the need for supranational regulation, nine rules for supranational minimum standards are proposed to protect both donor interests and the public good. A particular focus is directed to the commodification of oocytes with regard to the European principle of non-commercial, voluntary and altruistic donation. PMID:17393805

  10. Solving shortage in a priceless market: Insights from blood donation.

    PubMed

    Sun, Tianshu; Lu, Susan Feng; Jin, Ginger Zhe

    2016-07-01

    Shortage is common in many markets, such as those for human organs or blood, but the problem is often difficult to solve through price adjustment, given safety and ethical concerns. In this paper, we study two non-price methods that are often used to alleviate shortage for human blood. The first method is informing existing donors of a current shortage via a mobile message and encouraging them to donate voluntarily. The second method is asking the patient's family or friends to donate in a family replacement (FR) program at the time of shortage. Using 447,357 individual donation records across 8 years from a large Chinese blood bank, we show that both methods are effective in addressing blood shortage in the short run but have different implications for total blood supply in the long run. We compare the efficacy of these methods and discuss their applications under different scenarios to alleviate shortage. PMID:27263024

  11. Kidney organ donation: developing family practice initiatives to reverse inertia

    PubMed Central

    2010-01-01

    Background Kidney transplantation is associated with greater long term survival rates and improved quality of life compared with dialysis. Continuous growth in the number of patients with kidney failure has not been matched by an increase in the availability of kidneys for transplantation. This leads to long waiting lists, higher treatment costs and negative health outcomes. Discussion Misunderstandings, public uncertainty and issues of trust in the medical system, that limit willingness to be registered as a potential donor, could be addressed by community dissemination of information and new family practice initiatives that respond to individuals' personal beliefs and concerns regarding organ donation and transplantation. Summary Tackling both personal and public inertia on organ donation is important for any community oriented kidney donation campaign. PMID:20478042

  12. A phased consent policy for cord blood donation.

    PubMed

    Vawter, Dorothy E; Rogers-Chrysler, Gayl; Clay, Mary; Pittelko, Larrie; Therkelsen, Dave; Kim, Debora; McCullough, Jeffrey

    2002-10-01

    This article focuses on ethical and policy questions concerning when consent may be sought for the collection and donation of cord blood. It reviews the advantages and disadvantages of alternative times for securing consent, challenges common objections to seeking consent during labor or after collection, and describes a phased consent process--a process that permits consent during early labor to the ex utero collection of cord blood followed by after-consent collection to donation. The phased consent policy attends to the unique characteristics of cord blood collection and donation, respects donors and their families, maximizes the number and diversity of cord blood units collected, preserves the relationship between providers and patients, and preserves public trust in cord blood and other types of tissue banking. PMID:12423509

  13. Ethics in egg donation: past, present, and future.

    PubMed

    Klein, Joshua U; Sauer, Mark V

    2010-07-01

    Since the advent of clinical human egg donation just over 25 years ago, ethical considerations have been central to its successful application and popular acceptance. Early in its history, "essentialist" arguments questioning the moral validity of the practice altogether were commonplace. More recently, most academic discussion has been focused on "consequentialist" issues relating to practical approaches to egg donation that minimize ethically troublesome consequences. Three issues that have attracted a bulk of the attention in this regard are compensation, postmenopausal pregnancy, and egg sharing. Although much consensus has been reached on some very controversial issues, the enormous potential of increasingly successful oocyte cryopreservation, as well as emerging stem cell technologies, is very likely to provide abundant fuel for the continued debate of provocative and contentious ethical issues in human egg donation. PMID:20683796

  14. The introduction of breast milk donation in a Muslim country.

    PubMed

    al-Naqeeb, N A; Azab, A; Eliwa, M S; Mohammed, B Y

    2000-11-01

    Breast milk donation (wet-nursing) for full-term babies is a well-known practice in Kuwait, but it has never been organized formally in a neonatal intensive care unit (NICU) for preterm babies. Donor milk banking as conducted in Western society is not considered to be ethical in Muslim society, where the milk donor and the recipient are required to know each other. Human milk is known to decrease the incidence of necrotizing enterocolitis; improve host defenses, digestion, absorption of nutrients, gastrointestinal function, and neurodevelopment of the child; and contribute to maternal physical and psychological well-being. A culturally accepted approach to donor milk banking is proposed as a means of overcoming the ethical issues surrounding milk donation in Muslim society. This report addresses the first step in raising awareness of the valuable contribution of donor milk to preterm babies and the organization of human milk donation for use in an NICU. PMID:11155613

  15. Tissue and organ donation and transplantation in Iran.

    PubMed

    Goodarzi, Parisa; Aghayan, Hamid Reza; Larijani, Bagher; Rafiee, Alireza Baradaran; Falahzadeh, Khadijeh; Sahebjam, Mehrnaz; Ghaderi, Firoozeh; Arjmand, Babak

    2015-06-01

    Tissue and organ transplantation is one of the most promising treatments for some incurable diseases. Nowadays, transplantation is the common therapy in many countries. Unfortunately, availability of donated tissues and organs is limited. There are several factors which may affect donation rate for instance; social factors, culture, religion, and family decision. Accordingly, religious beliefs have a crucial role in tissue and organ donation and transplantation. Islam as a code of life has a comprehensive road map to lead mankind. Spiritual view of human life is considered to be much more valuable in Islam. Therefore, saving a human life is one of the most important Islamic teachings. In Iran as a Muslim country, tissue and organ transplantation program was established based on religious scholars' permission which has an essential role towards considerable development of the program in Iran. PMID:25194580

  16. How critical care nurses' roles and education affect organ donation.

    PubMed

    Jawoniyi, Oluwafunmilayo Ololade; Gormley, Kevin

    Organ and tissue dysfunction and failure cause high mortality rates around the world. Tissue and organs transplantation is an established, cost-effective, life-saving treatment for patients with organ failure. However, there is a large gap between the need for and the supply of donor organs. Acute and critical care nurses have a central role in the organ donation process, from identifying and assessing potential donors and supporting their families to involvement in logistics. Nurses with an in-depth knowledge of donation understand its clinical and technical aspects as well as the moral and legal considerations. Nurses have a major role to play in tackling organ and tissue shortages. Such a role cannot be adequately performed if nurses are not fully educated about donation and transplant. Such education could be incorporated into mandatory training and completed by all nurses. PMID:26153810

  17. An Analysis of Organ Donation Policy in the United States.

    PubMed

    Ahmad, Ghazi; Iftikhar, Sadia

    2016-01-01

    There is currently an organ shortage crisis in the United States. This paper analyzes the magnitude of the problem, the organ procurement programs in other developed countries as compared to the US, and discusses the changes that can be made to address this problem. With the opt-in or explicit-consent method currently practiced in the US, less that one third of the population consents to organ donation. In order to narrow the gap between the demand and supply of organs, steps need to be taken to improve the organ procurement infrastructure. The public needs to be educated about the dire need, the benefits and risks in organ donation, and living vs. deceased donation. [Full article available at http://rimed.org/rimedicaljournal-2016-05.asp, free with no login]. PMID:27128513

  18. Framing charitable donations as exceptional expenses increases giving.

    PubMed

    Sussman, Abigail B; Sharma, Eesha; Alter, Adam L

    2015-06-01

    Many articles have examined the psychological drivers of charitable giving, but little is known about how people mentally budget for charitable gifts. The present research aims to address this gap by investigating how perceptions of donations as exceptional (uncommon and infrequent) rather than ordinary (common and frequent) expenses might affect budgeting for and giving to charity. We provide the first demonstration that exceptional framing of an identical item can directly influence mental budgeting processes, and yield societal benefits. In 5 lab and field experiments, exceptional framing increased charitable behavior, and diminished the extent to which people considered the effect of the donation on their budgets. The current work extends our understanding of mental accounting and budgeting for charitable gifts, and demonstrates practical techniques that enable fundraisers to enhance the perceived exceptionality of donations. PMID:25893442

  19. Approaching families for organ donation: physicians are willing.

    PubMed

    Exley, M H; Serbin, M F; Goldstein, R M

    1992-09-01

    While current literature documents a critical disparity between the increasing demand for organs for transplantation and the relatively static supply, reasons for the shortage of donors are not well understood. Public opinion surveys describe a population willing to donate, but consent rates reported by organ procurement organizations suggest problems in the process of approaching families. This study of Texas physicians regarding their knowledge of laws related to brain death and to routine inquiry for organ donation and their attitudes toward the critical step of seeking consent from families indicates that physicians need more information about questions asked by families, would benefit from more structured hospital policies on routine inquiry, feel that physicians rather than nurses should approach families, and believe that the public is not well informed about donation. PMID:1462270

  20. Organ donation: attitude and knowledge of nurses in South Africa.

    PubMed

    Naude, A; Nel, E; Uys, H

    2002-01-01

    Various factors influence the process of organ donation. As a result, there is a shortage of organs for transplant. Poor communication and cooperation between transplant coordinators and intensive care nursing staff can lead to the non-referral of potential organ donors, which is detrimental to the process. The purpose of this research was to ascertain the attitude and knowledge of the transplant coordinators and intensive care nursing staff that work in intensive care units during organ donation. Contextual descriptive research was carried out by compiling literature-based questionnaires, one each for the transplant coordinators and intensive care nursing staff, and then analysing responses. The indications are that problem areas exist between the role players in the organ transplant process. Guidelines were drawn up for the improvement of communication and cooperation between them in order to promote organ donation. PMID:12035904

  1. The evolution of food donation with respect to waste prevention.

    PubMed

    Schneider, Felicitas

    2013-03-01

    The donation of food which is still edible can be seen as a specific application of urban mining as food is recovered for its original purpose - human intake. There are several projects implemented worldwide but due to a lack of data, scientific literature about the topic is rare. This paper summarises briefly the evolution of food donation activities and gives information on the differences and similarities of current organisations distributing food to people in need as well as the political, legal, social and logistical barriers and incentives which occur with respect to this topic. A concept for a food donation network is presented and impact on ecology, economy and society is discussed. PMID:23453166

  2. Mothers' attitudes towards donated breastmilk in Jos, Nigeria.

    PubMed

    Ighogboja, I S; Olarewaju, R S; Odumodu, C U; Okuonghae, H O

    1995-06-01

    In many developing countries, the use of pooled human milk is not widely accepted. Six hundred eighty breastfeeding mothers were interviewed to ascertain their acceptance of donated breastmilk. Their attitudes toward stored breastmilk, human milk banking, and breastfeeding in the event of human immunodeficiency virus (HIV) positivity were solicited. About 71 percent would not accept donated breastmilk for their baby while the rest would consent only if the donor were a close family relative, owing to fear of transfer of diseases (28 percent), fear of transfer of genetic traits (22 percent), and religious and cultural taboos (14 percent). However, 60 percent were willing to donate breastmilk. Only 38 percent would accept milk from a breastmilk bank. None would breastfeed if she were HIV positive. PMID:7619300

  3. The debate in Chile on organ donation revisited.

    PubMed

    Kottow Lang, Miguel Hugo

    2016-01-01

    The worldwide scarcity of cadaveric organs for transplants is on the rise, due in part to extended medical indications and longevity of chronic patients with organic insufficiencies. Chile has an extremely low donor rate of 6.7 per million. Although consent is presumed by law, and recently amended to include a “reciprocity principle”, nearly four million persons have expressed in writing their unwillingness to donate and, of those remaining, 53% of families have rejected donating the organs of their deceased. New proposals are urgently needed, even if some of them have previously been rejected: nonmaterial incentives, partial donations and unveiling anonymity to enhance personal ties between donors and recipients. Transparency, information and assistance are to be reinforced in order to regain trust in transplant procedures. PMID:27570970

  4. Normative consent and presumed consent for organ donation: a critique.

    PubMed

    Potts, Michael; Verheijde, Joseph L; Rady, Mohamed Y; Evans, David W

    2010-08-01

    Ben Saunders claims that actual consent is not necessary for organ donation due to 'normative consent', a concept he borrows from David Estlund. Combining normative consent with Peter Singer's 'greater moral evil principle', Saunders argues that it is immoral for an individual to refuse consent to donate his or her organs. If a presumed consent policy were thus adopted, it would be morally legitimate to remove organs from individuals whose wishes concerning donation are not known. This paper disputes Saunders' arguments. First, if death caused by the absence of organ transplant is the operational premise, then, there is nothing of comparable moral precedence under which a person is not obligated to donate. Saunders' use of Singer's principle produces a duty to donate in almost all circumstances. However, this premise is based on a flawed interpretation of cause and effect between organ availability and death. Second, given growing moral and scientific agreement that the organ donors in heart-beating and non-heart-beating procurement protocols are not dead when their organs are surgically removed, it is not at all clear that people have a duty to consent to their lives being taken for their organs. Third, Saunders' claim that there can be good reasons for refusing consent clashes with his claim that there is a moral obligation for everyone to donate their organs. Saunders' argument is more consistent with a conclusion of 'mandatory consent'. Finally, it is argued that Saunders' policy, if put into place, would be totalitarian in scope and would therefore be inconsistent with the freedom required for a democratic society. PMID:20663768

  5. Professional education and hospital development for organ donation.

    PubMed

    Fukushima, N; Konaka, S; Kato, O; Ashikari, J

    2012-05-01

    Because of the strict Organ Transplantation Act, only 81 brain dead (BD) organ donations had been performed in Japan for 13 years since 1997. The Act was revised on July 17, 2010, allowing, organs to be donated after BD with consent from the family, if the subject had not denied organ donation previously. This act has lead to an expectation of a 6-7-fold increase in BD donation. The 82 organ procurement coordinators (OPC) in Japan include 32 belonging to the Japanese Organ Network (JOT) and the others to each administrative division. JOT has guideline manuals of standard roles and procedures of OPC during organ procurement from BD and cardiac death donors. To manage the increased organ donations after the revision of the act, we have modified the education system. First, we modified the guideline manuals for OPC to correspond to the revised Transplant Act and governmental guidelines. Second, all OPC gathered in a meeting room to learn the new organ procurement system to deal with the revised Transplant Act and guidelines. Third, a special education program for 2 months was provided for the 10 newcomers. Last, the practical training in each donor case for newcomers was performed by older OPC. Topics of the education program were the revised transplant act and guidelines, family approach to organ donation, BD diagnosis, donor evaluation and management, organ procurement and preservation, allocation system, hospital development and family care. In the future, each OPC will be divided into special categories, such as the donor family OPC, the donor management OPC, and the operating room OPC. Therefore, we need to construct separate special education programs for each category. PMID:22564564

  6. Enclosure Requirements to Protect Personnel from Spinning Rotor Frailures at the Power Electronics and Electric Machinery Research Center

    SciTech Connect

    McKeever, John W

    2007-08-01

    Performance evaluation of electric motors is a major function of the Power Electronics and Electric Machinery Research Center (PEEMRC). Normally these motors have a fixed wire-wound stator and a rotating rotor, which may have conductors embedded in a ferromagnetic core (induction motors), magnets mounted on the surface of the ferromagnetic core with a thin metal or composite cylinder or ring to hold them in place, or magnets embedded in the ferromagnetic core. Most of the work currently involves the last two permanent magnet (PM) configurations. Although the stator of a radial-gap motor can absorb energy from many of the fragments ejected from the rotor during operation, the stator of an axial-gap motor is not positioned to provide significant protection. The housing of each motor can also absorb some of the energy. The most conservative approach, however, is to assume that all fragments from the rotor must be contained by a protective enclosure. An ideal enclosure is transparent. Manufacturers of such plastics as Lexan, Tuffak, and Cyrolon sell different variations of transparent enclosure material. Lexan is a polycarbonate sheet. Lexgard{reg_sign} is a penetration resistant material made by layering polycarbonate material between pieces of ordinary glass. A fragment striking a sheet of enclosure material will pierce the surface layer, but the layered polycarbonate-glass material is able to absorb the fragment's energy before it completes penetration. Tuffak{reg_sign} is Lexan polycarbonate. Cyrolon{reg_sign} bullet resistant material is acrylic sheet. The ability of the enclosure to stop a fragment depends on its thickness as well as the penetration capability of the fragment; for example, a lead fragment has much less penetrating capability than a steel fragment. Enclosure thicknesses are commercially available to provide several levels of protection. These levels depend on the momentum of the fragments and have been evaluated for some common types of ammunition

  7. Fresh Soy Oil Protects Against Vascular Changes in an Estrogen-Deficient Rat Model: An Electron Microscopy Study

    PubMed Central

    Adam, Siti Khadijah; Das, Srijit; Othman, Faizah; Jaarin, Kamsiah

    2009-01-01

    OBJECTIVE To observe the effects of consuming repeatedly heated soy oil on the aortic tissues of estrogen-deficient rats. METHODS Thirty female Sprague Dawley rats (200–250 g) were divided equally into five groups. One group served as the normal control (NC) group. The four treated groups were ovariectomized and were fed as follows: 2% cholesterol diet (OVXC); 2% cholesterol diet + fresh soy oil (FSO); 2% cholesterol diet + once-heated soy oil (1HSO); and 2% cholesterol diet + five-times-heated soy oil (5HSO). After four months, the rats were sacrificed, and the aortic tissues were obtained for histological studies. RESULTS After four months of feeding, the NC, FSO and 1HSO groups had a lower body weight gain compared to the OVXC and 5HSO groups. The tunica intima/media ratio in the 5HSO group was significantly thicker (p < 0.05) compared to the NC, OVXC and FSO groups. Electron microscopy showed that endothelial cells were normally shaped in the FSO and NC groups but irregular in the 1HSO and 5HSO groups. A greater number of collagen fibers and vacuoles were observed in the 5HSO group compared to the other treatment groups. CONCLUSIONS Fresh soy oil offered protection in the estrogen-deficient state, as these rats had similar features to those of the NC group. The damage to the tunica intima and the increase in the ratio of tunica intima/media thickness showed the deleterious effect of consuming repeatedly heated soy oil in castrated female rats. PMID:19936186

  8. Presumed consent for organ preservation in uncontrolled donation after cardiac death in the United States: a public policy with serious consequences

    PubMed Central

    Verheijde, Joseph L; Rady, Mohamed Y; McGregor, Joan

    2009-01-01

    and the absence of protection of individual autonomy, for the sake of maximizing procurement opportunities, have placed the current organ-donation system of opting-in in great jeopardy. Equally as important, current policies enabling and enhancing organ procurement practices, pose challenges to the constitutional rights of individuals in a pluralistic society as these policies are founded on flawed medical standards for declaring death. PMID:19772617

  9. Increasing organ donation by presumed consent and allocation priority: Chile.

    PubMed

    Zúñiga-Fajuri, Alejandra

    2015-03-01

    Chile, a middle-income country, recently joined Israel and Singapore as the world's only countries to require reciprocity as a precondition for organ transplantation. The Chilean reform includes opt-out provisions designed to foster donation and priority for organ transplantation for registered people. Although the reform has had serious difficulties in achieving its mission, it can be reviewed by other countries that seek to address the serious shortage of organs. As increased organ donation can substantially enhance or save more lives, the effect on organ availability due to incentives arising from rules of preference should not be underestimated. PMID:25767299

  10. Recommendations for donation after circulatory death kidney transplantation in Europe.

    PubMed

    van Heurn, L W Ernest; Talbot, David; Nicholson, Michael L; Akhtar, Mohammed Z; Sanchez-Fructuoso, Ana I; Weekers, Laurent; Barrou, Benoit

    2016-07-01

    Donation after circulatory death (DCD) donors provides an invaluable source for kidneys for transplantation. Over the last decade, we have observed a substantial increase in the number of DCD kidneys, particularly within Europe. We provide an overview of risk factors associated with DCD kidney function and survival and formulate recommendations from the sixth international conference on organ donation in Paris, for best-practice guidelines. A systematic review of the literature was performed using Ovid Medline, Embase and Cochrane databases. Topics are discussed, including donor selection, organ procurement, organ preservation, recipient selection and transplant management. PMID:26340168

  11. Increasing organ donation by presumed consent and allocation priority: Chile

    PubMed Central

    2015-01-01

    Abstract Chile, a middle-income country, recently joined Israel and Singapore as the world’s only countries to require reciprocity as a precondition for organ transplantation. The Chilean reform includes opt-out provisions designed to foster donation and priority for organ transplantation for registered people. Although the reform has had serious difficulties in achieving its mission, it can be reviewed by other countries that seek to address the serious shortage of organs. As increased organ donation can substantially enhance or save more lives, the effect on organ availability due to incentives arising from rules of preference should not be underestimated. PMID:25767299

  12. Comparing the effects of defaults in organ donation systems.

    PubMed

    van Dalen, Hendrik P; Henkens, Kène

    2014-04-01

    The ability of patients in many parts of the world to benefit from transplantation is limited by growing shortages of transplantable organs. The choice architecture of donation systems is said to play a pivotal role in explaining this gap. In this paper we examine the question how different defaults affect the decision to register as organ donor. Three defaults in organ donation systems are compared: mandated choice, presumed consent and explicit consent. Hypothetical choices from a national survey of 2069 respondents in May 2011 in the Netherlands - a country with an explicit consent system - suggests that mandated choice and presumed consent are more effective at generating registered donors than explicit consent. PMID:24561775

  13. Establishing a program of oocyte donation in Brazil.

    PubMed

    Nakamura, M S; Maciel, M C; Veiga, A; Asch, R H

    1992-02-01

    Oocyte donation is a novel alternative for the treatment of patients who have infertility associated with ovarian failure. Both IVF-ET and GIFT represent new techniques of treatment for this group of patients. Synchronization between donor and recipient is very simple and also flexible. In our study population, four patients received oocyte or embryo donation after at least 20 days of E replacement, and two of them conceived a clinical pregnancy. Apparently, the flexibility of our protocol of E replacement allows an extension of the proliferative phase in cases that need to have additional time to synchronize the recipient's cycle to that of the donors. PMID:1735499

  14. Recommendations for gamete and embryo donation: a committee opinion.

    PubMed

    2013-01-01

    This document provides the latest recommendations for evaluation of potential sperm, oocyte, and embryo donors, incorporating recent information about optimal screening and testing for sexually transmitted infections, genetic diseases, and psychological assessments. This revised document incorporates recent information from the U.S. Centers for Disease Control and Prevention, the US Food and Drug Administration, and the American Association of Tissue Banks, with which all programs offering gamete and embryo donation services must be thoroughly familiar, and replaces the document titled, "2008 Guidelines for Gamete and Embryo Donation: A Practice Committee Report," last published in Fertil Steril 2008;90:S30-44. PMID:23095142

  15. 3 CFR 8642 - Proclamation 8642 of March 31, 2011. National Donate Life Month, 2011

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., the number of Americans needing life-saving donations has far outstripped the number of available donors. As a result, people lose their lives each day while waiting. When each donation can touch...

  16. 48 CFR 45.603 - Abandonment, destruction or donation of excess personal property.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... officers may abandon, destroy, or donate to public bodies excess property that is not sensitive property... donate excess personal property to eligible donees in lieu of abandonment if the Government will not...

  17. 41 CFR 102-37.35 - Who handles the donation of surplus property?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of this part). The GSA may also donate to the American National Red Cross surplus property that was... donate surplus property that they would otherwise abandon or destroy directly to public bodies...

  18. 48 CFR 45.604-2 - Abandonment, destruction, or donation of surplus property.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... may abandon, destroy, or donate to public bodies surplus property that is not sensitive property, and... donate surplus property to eligible donees in lieu of abandonment if the Government will not bear any...

  19. 48 CFR 45.604-2 - Abandonment, destruction, or donation of surplus property.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... may abandon, destroy, or donate to public bodies surplus property that is not sensitive property, and... donate surplus property to eligible donees in lieu of abandonment if the Government will not bear any...

  20. 41 CFR 102-37.35 - Who handles the donation of surplus property?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of this part). The GSA may also donate to the American National Red Cross surplus property that was... donate surplus property that they would otherwise abandon or destroy directly to public bodies...

  1. Blood donation behaviour and beliefs among a sample of high school students in Mmabatho.

    PubMed

    Mwaba, K; Keikelame, M J

    1995-08-01

    This study was aimed at establishing the extent of blood donation and beliefs about donating blood among high school students in Mmabatho. A random sample of 40 Standard 10 students (20 males, 20 females; mean age = 20.8 years) was selected to participate in the study. A structured questionnaire was used to determined blood donation behaviour and accompanying beliefs. The results showed that although 80 percent of the participants believed that donating blood was important only 17.5 percent had actually ever donated blood. The data also showed that donating blood was a health risk or were uncertain if donating blood was safe. It is recommended that public appeals for blood donors should include information to dispel myths about dangers of donating blood. PMID:8697521

  2. Evidence for the involvement of cyclic electron transport in the protection of photosystem II against photoinhibition: influence of a new phenolic compound.

    PubMed

    Allakhverdiev, S I; Klimov, V V; Carpentier, R

    1997-04-01

    Organisms that perform oxygenic photosynthesis are subjected to inhibition of their photosynthetic functions when they are exposed to excessive illumination. Photoinhibition occurs mainly at the level of photosystem II, where a cyclic electron transport has often been proposed to be involved in photoprotection. However, a demonstration of direct protection by cyclic photosystem II against photoinhibitory damage has been lacking. In this report, we used the newly characterized compound 4-[methoxybis(trifluoromethyl)methyl]-2,6-dinitrophenylhydrazine methyl ketone (K-15), known to stimulate cyclic electron transport between the acceptor and donor sides of the photosystem [Klimov, V. V., Zharmukhamedov, S. K., Allakhverdiev, S. I., Kolobanova, L. P., & Baskakov, Y. A. (1993) Biol. Membr. 6, 715-732], to verify if photosystem II is significantly protected by cyclic electron transport against aerobic and anaerobic photoinhibitory damage. The photoinhibitory quenching of the maximal level of fluorescence and the decrease of the absorbance change at 685 nm related to pheophytin photoreduction observed during photoinhibitory illumination of untreated or Mn-depleted photosystem II submembrane fractions are significantly attenuated in the presence of K-15. The photodegradation of cytochrome b559 and the photobleaching of beta-carotene and chlorophyll-670 measured in Mn-depleted photosystem II preparations are also strongly retarded when K-15 is present. The detection, by photoacoustic spectroscopy, of the energy stored during the cyclic electron transport is also reported in Mn-depleted photosystem II submembrane fractions and in photosystem II reaction center complexes. This reaction is also gradually photoinhibited due to the progressive photodegradation of the required electron transport intermediates but is significantly more stable in the presence of K-15. It is deduced that cyclic electron transport around photosystem II constitutes an effective protective mechanism

  3. Motivations for Deceased Organ Donation Among Volunteers in China: A Qualitative Research Study.

    PubMed

    Yin, Zhike; Liu, Shan; Yan, Jin; Liu, Jia

    2016-01-01

    BACKGROUND To align with guiding principles on human organ and tissue transplantation published by the World Health Organization (WHO), the Red Cross Society of China (RCSC) launched a new nationwide organ donation program in 2010 to recruit organ donation volunteers. Despite severe shortage of donated organs, there is a very low rate of volunteering for organ donation among the Chinese population (only 0.03 donors per million population) in the national program. Motivating organ donation is the key to the success of organ transplantation in China. MATERIAL AND METHODS Semi-structured 45- to 60-min interviews were conducted among 34 volunteers. Data analysis was performed with Nvivo 8.0 software. RESULTS Six motivations for organ donation were identified: helping others/altruism, fulfilling long-cherished wishes, reducing the burdens, making the best use of everything, giving back to society, and life extension. Factors affecting the motivation of organ donation among volunteers in China included traditional values, personal experiences, role model effect, family support, and problems in the donation system. Possible strategies to improve organ donation included fostering a scientific concept of the body and death, focusing donation promotion efforts on certain groups, and simplifying the process of organ donation. CONCLUSIONS There are multiple reasons for Chinese people to register for organ donation, with helping others as the central motivation. PMID:27279558

  4. 31 CFR 585.521 - Donations of food to relieve human suffering authorized.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Donations of food to relieve human... Donations of food to relieve human suffering authorized. (a) Specific licenses may be issued on a case-by-case basis to permit exportation to the FRY (S&M) of donated food intended to relieve human...

  5. Organ Donation and Transplantation for Older Donors and Recipients: Resources from the U.S. Government

    MedlinePlus

    ... NeuroBioBank How to Become a Donor Why Donate? National Institute on Neurological Disorders and Stroke Brain and Tissue Banks Resources Alzheimer’s Foundation of America Your Brain: A Priceless Donation to Science (PDF, 245K) Brain donation for Alzheimer’s disease patients ...

  6. 41 CFR 102-37.125 - What are some donations that do not require GSA's approval?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the Small Business Administration to small disadvantaged businesses under 13 CFR part 124; and (4... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What are some donations... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY Holding Agency § 102-37.125 What are some donations...

  7. 41 CFR 102-37.90 - What are GSA's responsibilities in the donation of surplus property?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... responsibilities in the donation of surplus property? 102-37.90 Section 102-37.90 Public Contracts and Property... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY General Services Administration (GSA) § 102-37.90 What are GSA's responsibilities in the donation of surplus property? The General Services...

  8. 48 CFR 52.226-6 - Promoting excess food donation to nonprofit organizations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... donation to nonprofit organizations. 52.226-6 Section 52.226-6 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.226-6 Promoting excess food donation to nonprofit organizations. As prescribed in 26.404, insert the following clause: PROMOTING EXCESS FOOD DONATION TO NONPROFIT...

  9. 48 CFR 52.226-6 - Promoting excess food donation to nonprofit organizations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... donation to nonprofit organizations. 52.226-6 Section 52.226-6 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.226-6 Promoting excess food donation to nonprofit organizations. As prescribed in 26.404, insert the following clause: PROMOTING EXCESS FOOD DONATION TO NONPROFIT...

  10. 41 CFR 102-37.90 - What are GSA's responsibilities in the donation of surplus property?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... responsibilities in the donation of surplus property? 102-37.90 Section 102-37.90 Public Contracts and Property... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY General Services Administration (GSA) § 102-37.90 What are GSA's responsibilities in the donation of surplus property? The General Services...

  11. 44 CFR 206.6 - Donation or loan of Federal equipment and supplies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Donation or loan of Federal... Donation or loan of Federal equipment and supplies. (a) In any major disaster or emergency, the... governments for use and distribution by them for the purposes of the Stafford Act. (b) A donation or loan...

  12. 48 CFR 52.226-6 - Promoting excess food donation to nonprofit organizations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... donation to nonprofit organizations. 52.226-6 Section 52.226-6 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.226-6 Promoting excess food donation to nonprofit organizations. As prescribed in 26.404, insert the following clause: Promoting Excess Food Donation to Nonprofit...

  13. 11 CFR 110.20 - Prohibition on contributions, donations, expenditures, independent expenditures, and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... meaning as in 11 CFR 300.2(d). (2) Donation has the same meaning as in 11 CFR 300.2(e). (3) Foreign... under 11 CFR 100.5. (d) Contributions and donations by foreign nationals for office buildings. A foreign... national shall not, directly or indirectly, make a donation to an inaugural committee, as defined in 11...

  14. 44 CFR 206.6 - Donation or loan of Federal equipment and supplies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Donation or loan of Federal... Donation or loan of Federal equipment and supplies. (a) In any major disaster or emergency, the... governments for use and distribution by them for the purposes of the Stafford Act. (b) A donation or loan...

  15. 48 CFR 52.226-6 - Promoting excess food donation to nonprofit organizations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... donation to nonprofit organizations. 52.226-6 Section 52.226-6 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.226-6 Promoting excess food donation to nonprofit organizations. As prescribed in 26.404, insert the following clause: PROMOTING EXCESS FOOD DONATION TO NONPROFIT...

  16. 41 CFR 102-37.125 - What are some donations that do not require GSA's approval?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the Small Business Administration to small disadvantaged businesses under 13 CFR part 124; and (4... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What are some donations... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY Holding Agency § 102-37.125 What are some donations...

  17. 44 CFR 206.6 - Donation or loan of Federal equipment and supplies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Donation or loan of Federal... Donation or loan of Federal equipment and supplies. (a) In any major disaster or emergency, the... governments for use and distribution by them for the purposes of the Stafford Act. (b) A donation or loan...

  18. 41 CFR 102-37.90 - What are GSA's responsibilities in the donation of surplus property?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... responsibilities in the donation of surplus property? 102-37.90 Section 102-37.90 Public Contracts and Property... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY General Services Administration (GSA) § 102-37.90 What are GSA's responsibilities in the donation of surplus property? The General Services...

  19. 41 CFR 102-41.170 - Is unclaimed personal property available for donation?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... property available for donation? 102-41.170 Section 102-41.170 Public Contracts and Property Management... Personal Property § 102-41.170 Is unclaimed personal property available for donation? No, unclaimed personal property is not available for donation because reimbursement at fair market value is required....

  20. 41 CFR 102-37.125 - What are some donations that do not require GSA's approval?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the Small Business Administration to small disadvantaged businesses under 13 CFR part 124; and (4... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What are some donations... PROPERTY 37-DONATION OF SURPLUS PERSONAL PROPERTY Holding Agency § 102-37.125 What are some donations...